ERIC Educational Resources Information Center
Pavlova, Marina A.; Krageloh-Mann, Ingeborg
2013-01-01
Brain lesions to the white matter in peritrigonal regions, periventricular leukomalacia, in children who were born prematurely represent an important model for studying limitations on brain development. The lesional pattern is of early origin and bilateral, that constrains the compensatory potential of the brain. We suggest that (i) topography and…
Entrapment of the Temporal Horn as a Cause of Pure Wernicke Aphasia: Case Report.
Spallone, Aldo; Belvisi, Daniele; Marsili, Luca
2015-07-01
Entrapment of the temporal horn is an extremely rare pathologic condition occurring as a result of surgery for tumors, intraventricular infections, hemorrhage, or traumatic events involving the peritrigonal area. We report a case of a 58-year-old man who presented with pure Wernicke aphasia (never described before in the albeit rare cases of isolated temporal horn dilatation) that regressed completely following successful ventriculoperitoneal shunting. The relevant literature is also briefly reviewed.
Büyükünal, S N; Kaner, G; Celayir, S
1989-06-01
The aim of this study was to find a new alternate method for bladder exstrophies with small capacity and inelasticity, and to resolve complications of other bladder augmentation techniques. In 50 Wistar albino rats, a large bladder defect was created excising at least one half of their original bladder, keeping the peritrigonal zone intact. In each rat, a 2.5 x 1-cm inferiorly based rectus abdominus muscle flap was prepared from the lower abdominal quadrant. This flap was then rotated to cover the bladder defect. The inner layer formed by the peritoneum was sutured to the edges of the bladder defect by 6-0 separate sutures. The post-operative radiologic and scintigraphic examination of the urinary system done at different intervals showed no difference from that of normal rats. The only observed disadvantage of this technique was the formation of calculi in the bladder in 8/50 rats in the late post-operative period. Post-mortem histopathologic investigations performed at different intervals showed the inner layer of the flap to be completely covered by the transitional urinary epithelium of the bladder. We think this technique is easy to perform, non-time-consuming, and has a low complication rate. It may be useful in infants with small, noncompliant, inelastic bladder exstrophies.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-28
...-AA00 Safety Zone; Military Ocean Terminal Concord Safety Zone, Suisun Bay, Military Ocean Terminal... Guard is establishing a safety zone in the navigable waters of Suisun Bay near Military Ocean Terminal Concord, CA in support of military onload and offload operations. This safety zone is established to...
Code of Federal Regulations, 2014 CFR
2014-07-01
... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Safety zone; Military Ocean Terminal Concord Safety Zone, Suisun Bay, Military Ocean Terminal Concord, CA. 165.1198 Section 165.1198... Limited Access Areas Eleventh Coast Guard District § 165.1198 Safety zone; Military Ocean Terminal Concord...
Code of Federal Regulations, 2013 CFR
2013-07-01
... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Safety zone; Military Ocean Terminal Concord Safety Zone, Suisun Bay, Military Ocean Terminal Concord, CA. 165.1198 Section 165.1198... Limited Access Areas Eleventh Coast Guard District § 165.1198 Safety zone; Military Ocean Terminal Concord...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-07
...-AA00 Safety Zone; San Diego International Airport Terminal Two West Grand Opening Fireworks; San Diego... Opening of Lindbergh Airport Terminal Two West on August 8, 2013. This temporary safety zone is necessary... Diego International Airport Terminal Two grand opening. This safety zone is necessary to provide for the...
49 CFR 222.51 - Under what conditions will quiet zone status be terminated?
Code of Federal Regulations, 2013 CFR
2013-10-01
...-Quiet Zones § 222.51 Under what conditions will quiet zone status be terminated? (a) New Quiet Zones... 49 Transportation 4 2013-10-01 2013-10-01 false Under what conditions will quiet zone status be terminated? 222.51 Section 222.51 Transportation Other Regulations Relating to Transportation (Continued...
49 CFR 222.51 - Under what conditions will quiet zone status be terminated?
Code of Federal Regulations, 2014 CFR
2014-10-01
...-Quiet Zones § 222.51 Under what conditions will quiet zone status be terminated? (a) New Quiet Zones... 49 Transportation 4 2014-10-01 2014-10-01 false Under what conditions will quiet zone status be terminated? 222.51 Section 222.51 Transportation Other Regulations Relating to Transportation (Continued...
49 CFR 222.51 - Under what conditions will quiet zone status be terminated?
Code of Federal Regulations, 2012 CFR
2012-10-01
...-Quiet Zones § 222.51 Under what conditions will quiet zone status be terminated? (a) New Quiet Zones... 49 Transportation 4 2012-10-01 2012-10-01 false Under what conditions will quiet zone status be terminated? 222.51 Section 222.51 Transportation Other Regulations Relating to Transportation (Continued...
33 CFR 165.1199 - Security Zones; Military Ocean Terminal Concord (MOTCO), Concord, California.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Security Zones; Military Ocean... Coast Guard District § 165.1199 Security Zones; Military Ocean Terminal Concord (MOTCO), Concord..., extending from the surface to the sea floor, within 500 yards of the three Military Ocean Terminal Concord...
33 CFR 165.1199 - Security Zones; Military Ocean Terminal Concord (MOTCO), Concord, California.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Security Zones; Military Ocean... Coast Guard District § 165.1199 Security Zones; Military Ocean Terminal Concord (MOTCO), Concord..., extending from the surface to the sea floor, within 500 yards of the three Military Ocean Terminal Concord...
33 CFR 165.1199 - Security Zones; Military Ocean Terminal Concord (MOTCO), Concord, California.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Security Zones; Military Ocean... Coast Guard District § 165.1199 Security Zones; Military Ocean Terminal Concord (MOTCO), Concord..., extending from the surface to the sea floor, within 500 yards of the three Military Ocean Terminal Concord...
33 CFR 165.1199 - Security Zones; Military Ocean Terminal Concord (MOTCO), Concord, California.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Security Zones; Military Ocean... Coast Guard District § 165.1199 Security Zones; Military Ocean Terminal Concord (MOTCO), Concord..., extending from the surface to the sea floor, within 500 yards of the three Military Ocean Terminal Concord...
33 CFR 165.1199 - Security Zones; Military Ocean Terminal Concord (MOTCO), Concord, California.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Security Zones; Military Ocean... Coast Guard District § 165.1199 Security Zones; Military Ocean Terminal Concord (MOTCO), Concord..., extending from the surface to the sea floor, within 500 yards of the three Military Ocean Terminal Concord...
33 CFR 165.1156 - Safety Zone; Offshore Marine Terminal, El Segundo, CA.
Code of Federal Regulations, 2014 CFR
2014-07-01
... § 165.1156 Safety Zone; Offshore Marine Terminal, El Segundo, CA. (a) Location. The following area is a safety zone: All waters of Santa Monica Bay, from surface to bottom, enclosed by a line beginning at... Terminal, El Segundo, CA. 165.1156 Section 165.1156 Navigation and Navigable Waters COAST GUARD, DEPARTMENT...
33 CFR 165.1156 - Safety Zone; Offshore Marine Terminal, El Segundo, CA.
Code of Federal Regulations, 2013 CFR
2013-07-01
... § 165.1156 Safety Zone; Offshore Marine Terminal, El Segundo, CA. (a) Location. The following area is a safety zone: All waters of Santa Monica Bay, from surface to bottom, enclosed by a line beginning at... Terminal, El Segundo, CA. 165.1156 Section 165.1156 Navigation and Navigable Waters COAST GUARD, DEPARTMENT...
33 CFR 165.1156 - Safety Zone; Offshore Marine Terminal, El Segundo, CA.
Code of Federal Regulations, 2011 CFR
2011-07-01
... § 165.1156 Safety Zone; Offshore Marine Terminal, El Segundo, CA. (a) Location. The following area is a safety zone: All waters of Santa Monica Bay, from surface to bottom, enclosed by a line beginning at... Terminal, El Segundo, CA. 165.1156 Section 165.1156 Navigation and Navigable Waters COAST GUARD, DEPARTMENT...
33 CFR 165.1156 - Safety Zone; Offshore Marine Terminal, El Segundo, CA.
Code of Federal Regulations, 2012 CFR
2012-07-01
... § 165.1156 Safety Zone; Offshore Marine Terminal, El Segundo, CA. (a) Location. The following area is a safety zone: All waters of Santa Monica Bay, from surface to bottom, enclosed by a line beginning at... Terminal, El Segundo, CA. 165.1156 Section 165.1156 Navigation and Navigable Waters COAST GUARD, DEPARTMENT...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-02-01
... 1625-AA00 Safety Zone; Alaska Marine Highway System Port Valdez Ferry Terminal, Port Valdez; Valdez, AK... Alaska Marine Highway System (AMHS) Port Valdez Ferry Terminal. The purpose of the safety zone is to... Security Delegation No. 0170.1. A representative of the Alaska Marine Highway System requested that the...
33 CFR 165.1710 - Port Valdez and Valdez Narrows, Valdez, Alaska-security zones.
Code of Federal Regulations, 2010 CFR
2010-07-01
... following areas are security zones: (1) Trans-Alaska Pipeline (TAPS) Valdez Terminal complex (Terminal), Valdez, Alaska and TAPS tank vessels. All waters enclosed within a line beginning on the southern... TAPS tank vessel maneuvering to approach, moor, unmoor or depart the TAPS Terminal or transiting...
Capillary zone electrophoresis-mass spectrometer interface
D`Silva, A.
1996-08-06
A device for providing equal electrical potential between two loci unconnected by solid or liquid electrical conductors is provided. The device comprises a first electrical conducting terminal, a second electrical conducting terminal connected to the first terminal by a rigid dielectric structure, and an electrically conducting gas contacting the first and second terminals. This device is particularly suitable for application in the electrospray ionization interface between a capillary zone electrophoresis apparatus and a mass spectrometer. 1 fig.
Capillary zone electrophoresis-mass spectrometer interface
D'Silva, Arthur
1996-08-06
A device for providing equal electrical potential between two loci unconnected by solid or liquid electrical conducts is provided. The device comprises a first electrical conducting terminal, a second electrical conducting terminal connected to the first terminal by a rigid dielectric structure, and an electrically conducting gas contacting the first and second terminals. This device is particularly suitable for application in the electrospray ionization interface between a capillary zone electrophoresis apparatus and a mass spectrometer.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Safety and Security Zone; Cove Point Liquefied Natural Gas Terminal, Chesapeake Bay, Maryland. 165.502 Section 165.502 Navigation and... Areas Fifth Coast Guard District § 165.502 Safety and Security Zone; Cove Point Liquefied Natural Gas...
Code of Federal Regulations, 2011 CFR
2011-07-01
... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Safety and Security Zone; Cove Point Liquefied Natural Gas Terminal, Chesapeake Bay, Maryland. 165.502 Section 165.502 Navigation and... Areas Fifth Coast Guard District § 165.502 Safety and Security Zone; Cove Point Liquefied Natural Gas...
76 FR 47540 - Voluntary Termination of Subzone Status; Chrysler Group, LLC, Newark, DE
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-05
... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Order No. 1775] Voluntary Termination of Subzone Status; Chrysler Group, LLC, Newark, DE Pursuant to its authority under the Foreign-Trade Zones Act of June 18, 1934, as amended (19 U.S.C. 81a-81u), the Foreign-Trade Zones Board (the Board) adopts the...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-24
... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Order No. 1821] Voluntary Termination of Foreign-Trade Subzone 9D, Maui Pineapple Company, Ltd., Kahului, Maui, HI Pursuant to its authority under the Foreign-Trade Zones Act of June 18, 1934, as amended (19 U.S.C. 81a-81u), and the Foreign-Trade Zones...
Pavlova, Marina A; Krägeloh-Mann, Ingeborg
2013-04-01
Brain lesions to the white matter in peritrigonal regions, periventricular leukomalacia, in children who were born prematurely represent an important model for studying limitations on brain development. The lesional pattern is of early origin and bilateral, that constrains the compensatory potential of the brain. We suggest that (i) topography and severity of periventricular lesions may have a long-term predictive value for cognitive and social capabilities in preterm birth survivors; and (ii) periventricular lesions may impact cognitive and social functions by affecting brain connectivity, and thereby, the dissociable neural networks underpinning these functions. A further pathway to explore is the relationship between cerebral palsy and cognitive outcome. Restrictions caused by motor disability may affect active exploration of surrounding and social participation that may in turn differentially impinge on cognitive development and social cognition. As an outline for future research, we underscore sex differences, as the sex of a preterm newborn may shape the mechanisms by which the developing brain is affected.
NASA Technical Reports Server (NTRS)
Purcell, I. M.; Perachio, A. A.
1997-01-01
Anterograde labeling techniques were used to examine peripheral innervation patterns of vestibular efferent neurons in the crista ampullares of the gerbil. Vestibular efferent neurons were labeled by extracellular injections of biocytin or biotinylated dextran amine into the contralateral or ipsilateral dorsal subgroup of efferent cell bodies (group e) located dorsolateral to the facial nerve genu. Anterogradely labeled efferent terminal field varicosities consist mainly of boutons en passant with fewer of the terminal type. The bouton swellings are located predominately in apposition to the basolateral borders of the afferent calyces and type II hair cells, but several boutons were identified close to the hair cell apical border on both types. Three-dimensional reconstruction and morphological analysis of the terminal fields from these cells located in the sensory neuroepithelium of the anterior, horizontal, and posterior cristae were performed. We show that efferent neurons densely innervate each end organ in widespread terminal fields. Subepithelial bifurcations of parent axons were minimal, with extensive collateralization occurring after the axons penetrated the basement membrane of the neuroepithelium. Axonal branching ranged between the 6th and 27th orders and terminal field collecting area far exceeds that of the peripheral terminals of primary afferent neurons. The terminal fields of the efferent neurons display three morphologically heterogeneous types: central, peripheral, and planum. All cell types possess terminal fields displaying a high degree of anisotropy with orientations typically parallel to or within +/-45 degrees of the longitudinal axis if the crista. Terminal fields of the central and planum zones predominately project medially toward the transverse axis from the more laterally located penetration of the basement membrane by the parent axon. Peripheral zone terminal fields extend predominately toward the planum semilunatum. The innervation areas of efferent terminal fields display a trend from smallest to largest for the central, peripheral, and planum types, respectively. Neurons that innervate the central zone of the crista do not extend into the peripheral or planum regions. Conversely, those neurons with terminal fields in the peripheral or planum regions do not innervate the central zone of the sensory neuroepithelium. The central zone of the crista is innervated preferentially by efferent neurons with cell bodies located in the ipsilateral group e. The peripheral and planum zones of the crista are innervated preferentially by efferent neurons with cell bodies located in the contralateral group e. A model incorporating our anatomic observations is presented describing an ipsilateral closed-loop feedback between ipsilateral efferent neurons and the periphery and an open-loop feed-forward innervation from contralateral efferent neurons. A possible role for the vestibular efferent neurons in the modulation of semicircular canal afferent response dynamics is proposed.
Replication landscape of the human genome
Petryk, Nataliya; Kahli, Malik; d'Aubenton-Carafa, Yves; Jaszczyszyn, Yan; Shen, Yimin; Silvain, Maud; Thermes, Claude; Chen, Chun-Long; Hyrien, Olivier
2016-01-01
Despite intense investigation, human replication origins and termini remain elusive. Existing data have shown strong discrepancies. Here we sequenced highly purified Okazaki fragments from two cell types and, for the first time, quantitated replication fork directionality and delineated initiation and termination zones genome-wide. Replication initiates stochastically, primarily within non-transcribed, broad (up to 150 kb) zones that often abut transcribed genes, and terminates dispersively between them. Replication fork progression is significantly co-oriented with the transcription. Initiation and termination zones are frequently contiguous, sometimes separated by regions of unidirectional replication. Initiation zones are enriched in open chromatin and enhancer marks, even when not flanked by genes, and often border ‘topologically associating domains' (TADs). Initiation zones are enriched in origin recognition complex (ORC)-binding sites and better align to origins previously mapped using bubble-trap than λ-exonuclease. This novel panorama of replication reveals how chromatin and transcription modulate the initiation process to create cell-type-specific replication programs. PMID:26751768
78 FR 12716 - Expansion of Foreign-Trade Zone 49 Newark/Elizabeth, New Jersey
Federal Register 2010, 2011, 2012, 2013, 2014
2013-02-25
... that would terminate authority on February 28, 2018 for Site 13 if no activity has occurred under FTZ... terminate authority where no activity has occurred under FTZ procedures by February 28, 2018. Signed at... Administration, Alternate Chairman, Foreign-Trade Zones Board. Attest: Andrew McGilvray, Executive Secretary. [FR...
NASA Technical Reports Server (NTRS)
Liggett, M. A. (Principal Investigator); Childs, J. F.
1974-01-01
The author has identified the following significant results. The pattern of faulting associated with the termination of the Death Valley-Furnace Creek Fault Zone in northern Fish Lake Valley, Nevada was studied in ERTS-1 MSS color composite imagery and color IR U-2 photography. Imagery analysis was supported by field reconnaissance and low altitude aerial photography. The northwest-trending right-lateral Death Valley-Furnace Creek Fault Zone changes northward to a complex pattern of discontinuous dip slip and strike slip faults. This fault pattern terminates to the north against an east-northeast trending zone herein called the Montgomery Fault Zone. No evidence for continuation of the Death Valley-Furnace Creek Fault Zone is recognized north of the Montgomery Fault Zone. Penecontemporaneous displacement in the Death Valley-Furnace Creek Fault Zone, the complex transitional zone, and the Montgomery Fault Zone suggests that the systems are genetically related. Mercury mineralization appears to have been localized along faults recognizable in ERTS-1 imagery within the transitional zone and the Montgomery Fault Zone.
Cyclic flow underground coal gasification process
Bissett, Larry A.
1978-01-01
The present invention is directed to a method of in situ coal gasification for providing the product gas with an enriched concentration of carbon monoxide. The method is practiced by establishing a pair of combustion zones in spaced-apart boreholes within a subterranean coal bed and then cyclically terminating the combustion in the first of the two zones to establish a forward burn in the coal bed so that while an exothermic reaction is occurring in the second combustion zone to provide CO.sub.2 -laden product gas, an endothermic CO-forming reaction is occurring in the first combustion zone between the CO.sub.2 -laden gas percolating thereinto and the hot carbon in the wall defining the first combustion zone to increase the concentration of CO in the product gas. When the endothermic reaction slows to a selected activity the roles of the combustion zones are reversed by re-establishing an exothermic combustion reaction in the first zone and terminating the combustion in the second zone.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-22
..., FTZ 121's existing Sites 1, 2 and 3, and new Sites 5 and 6 would be categorized as magnet sites... general-purpose zone project, to a five-year ASF sunset provision for magnet sites that would terminate... ASF sunset provision that would terminate authority for magnet Site 5 if not activated by June 30...
Processing α-mercuric iodide by zone refining
NASA Astrophysics Data System (ADS)
Burger, A.; Morgan, S. H.; Henderson, D. O.; Biao, Y.; Zhang, K.; Silberman, E.; Nason, D.; van den Berg, L.; Ortale-Baccash, C.; Cross, E.
1993-03-01
An investigation is being conducted on zone refining α-mercuric iodide. Analytical studies using differential scanning calorimetry and anion chromatography indicate that impurities are accumulated mainly at the end where zone travel terminates. Early results indicate that single crystals can be readily grown from zone-refined material.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Short, Mark; Chliquete, Carlos
2011-01-20
The pulsating dynamics of gaseous detonations with a model two-step chain-branching kinetic mechanism are studied both numerically and asymptotically. The model studied here was also used in [4], [3] and [2] and mimics the attributes of some chain-branching reaction mechanisms. Specifically, the model comprises a chain-initiationlbranching zone with an Arrhenius temperature-sensitive rate behind the detonation shock where fuel is converted into chain-radical with no heat release. This is followed by a chain-termination zone having a temperature insensitive rate where the exothermic heat of reaction is released. The lengths of these two zones depend on the relative rates of each stage.more » It was determined in [4] and [3] via asymptotic and numerical analysis that the ratio of the length of the chain-branching zone to that of the chain-initation zone relative to the size of the von Neumann state scaled activation energy in the chain initiation/branching zone has a primary influence of the stability of one-dimensional pulsating instability behavior for this model. In [2], the notion of a specific stability parameter related to this ratio was proposed that determines the boundary between stable and unstable waves. In [4], a slow-time varying asymptotic study was conducted of pulsating instability of Chapman-Jouguet (CJ) detonations with the above two-step rate model, assuming a large activation energy for the chain-initiation zone and a chain-termination zone longer than the chain-initiation zone. Deviations D{sub n}{sup (1)} ({tau}) of the detonation velocity from Chapman-Jouguet were of the order of the non-dimensional activation energy. Solutions were sought for a pulsation timescale of the order of the non-dimensional activation energy times the particle transit time through the induction zone. On this time-scale, the evolution of the chain-initation zone is quasi-steady. In [4], a time-dependent non-linear evolution equation for D{sub n}{sup (1)} ({tau}) was then constructed via a perturbation procedure for cases where the ratio of the length of the chain-termination zone to chain-initiation zone was less than the non-dimensional activation energy. To leading order, the steady CJ detonation was found to be unstable; higher-order corrections lead to the construction of a stability limit between stable and unsteady pulsating solutions. One conclusion from this study is that for a stability limit to occur at leading order, the period of pulsation of the detonation must occur on the time scale of particle passage through the longer chain-termination zone, while the length of the chain-termination zone must be of order of the non-dimensional activation energy longer than the chain-initiation zone. The relevance of these suggested scalings was verified via numerical solutions of the full Euler system in [3], and formed the basis of the stability parameter criteria suggested in [2]. In the following, we formulate an asymptotic study based on these new suggested scales, studying the implications for describing pulsating behavior in gaseous chain-branching detonations. Specifically, we find that the chain-induction zone structure is the same as that studied in [4]. However, the study of unsteady evolution in the chain-termination region is now governed by a set of asymptotically derived nonlinear POEs. Equations for the linear stablity behavior of this set of POE's is obtained, while the nonlinear POEs are solved numerically using a shock-attached, shock-fitting method developed by Henrick et aJ. [1]. The results thus far show that the stability threshold calculated using the new ratio of the chain-termination zone length to that of the chain-initiation zone yields a marked improvement over [2]. Additionally, solutions will be compared with predictions obtained from the solution of the full Euler system. Finally, the evolution equation previously derived in [4] has been generalized to consider both arbitrary reaction orders and any degree of overdrive.« less
49 CFR 372.237 - Cameron, Hidalgo, Starr, and Willacy Counties, TX.
Code of Federal Regulations, 2011 CFR
2011-10-01
... REGULATIONS EXEMPTIONS, COMMERCIAL ZONES, AND TERMINAL AREAS Commercial Zones § 372.237 Cameron, Hidalgo, Starr, and Willacy Counties, TX. (a) Transportation within a zone comprised of Cameron, Hidalgo, Starr... common control, management, or arrangement for shipment to or from points beyond such zone, is partially...
49 CFR 372.237 - Cameron, Hidalgo, Starr, and Willacy Counties, TX.
Code of Federal Regulations, 2012 CFR
2012-10-01
... REGULATIONS EXEMPTIONS, COMMERCIAL ZONES, AND TERMINAL AREAS Commercial Zones § 372.237 Cameron, Hidalgo, Starr, and Willacy Counties, TX. (a) Transportation within a zone comprised of Cameron, Hidalgo, Starr... common control, management, or arrangement for shipment to or from points beyond such zone, is partially...
49 CFR 372.237 - Cameron, Hidalgo, Starr, and Willacy Counties, TX.
Code of Federal Regulations, 2014 CFR
2014-10-01
... REGULATIONS EXEMPTIONS, COMMERCIAL ZONES, AND TERMINAL AREAS Commercial Zones § 372.237 Cameron, Hidalgo, Starr, and Willacy Counties, TX. (a) Transportation within a zone comprised of Cameron, Hidalgo, Starr... common control, management, or arrangement for shipment to or from points beyond such zone, is partially...
49 CFR 372.237 - Cameron, Hidalgo, Starr, and Willacy Counties, TX.
Code of Federal Regulations, 2013 CFR
2013-10-01
... REGULATIONS EXEMPTIONS, COMMERCIAL ZONES, AND TERMINAL AREAS Commercial Zones § 372.237 Cameron, Hidalgo, Starr, and Willacy Counties, TX. (a) Transportation within a zone comprised of Cameron, Hidalgo, Starr... common control, management, or arrangement for shipment to or from points beyond such zone, is partially...
49 CFR 372.237 - Cameron, Hidalgo, Starr, and Willacy Counties, TX.
Code of Federal Regulations, 2010 CFR
2010-10-01
... REGULATIONS EXEMPTIONS, COMMERCIAL ZONES, AND TERMINAL AREAS Commercial Zones § 372.237 Cameron, Hidalgo, Starr, and Willacy Counties, TX. (a) Transportation within a zone comprised of Cameron, Hidalgo, Starr... common control, management, or arrangement for shipment to or from points beyond such zone, is partially...
Maciejewska, Izabela; Cowan, Cameron; Svoboda, Kathy; Butler, William T; D'Souza, Rena; Qin, Chunlin
2009-02-01
Multiple studies have shown that dentin matrix protein 1 (DMP1) is essential for bone and dentin mineralization. After post-translational proteolytic cleavage, DMP1 exists within the extracellular matrix of bone and dentin as an NH2-terminal fragment, a COOH-terminal fragment, and the proteoglycan form of the NH2-terminal fragment (DMP1-PG). To begin to assess the biological function of each fragment, we evaluated the distribution of both fragments in the rat tooth and bone using antibodies specific to the NH2-terminal and COOH-terminal regions of DMP1 and confocal microscopy. In rat first molar organs, the NH2-terminal fragment localized to predentin, whereas the COOH-terminal fragment was mainly restricted to mineralized dentin. In the growth plate of bone, the NH2-terminal fragment appeared in the proliferation and hypertrophic zones, whereas the COOH-terminal fragment occupied the ossification zone. Forster resonance energy transfer analysis showed colocalization of both fragments of DMP1 in odontoblasts and predentin, as well as hypertrophic chondrocytes within the growth plates of bone. The biochemical analysis of bovine teeth showed that predentin is rich in DMP1-PG, whereas mineralized dentin primarily contains the COOH-terminal fragment. We conclude that the differential patterns of expression of NH2-terminal and COOH-terminal fragments of DMP1 reflect their potentially distinct roles in the biomineralization of dentin and bone matrices.
77 FR 52681 - Reorganization and Expansion of Foreign-Trade Zone 87 Lake Charles, LA
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-30
... Foreign-Trade Zone 87 Lake Charles, LA Pursuant to its authority under the Foreign-Trade Zones Act of June 18, 1934, as amended (19 U.S.C. 81a-81u), the Foreign-Trade Zones Board (the Board) adopts the following Order: Whereas, the Lake Charles Harbor & Terminal District, grantee of Foreign-Trade Zone 87...
33 CFR 165.T0704 - Safety Zone: Savannah River, Savannah, Georgia.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Safety Zone: Savannah River....T0704 Safety Zone: Savannah River, Savannah, Georgia. (a) Location. The following area is a safety zone: Two hundred foot radius around Garden City Terminal, approximate position 32 degrees 8 minutes, N, 81...
Clarinet (CLA-1), a novel active zone protein required for synaptic vesicle clustering and release
Nelson, Jessica; Richmond, Janet E; Colón-Ramos, Daniel A; Shen, Kang
2017-01-01
Active zone proteins cluster synaptic vesicles at presynaptic terminals and coordinate their release. In forward genetic screens, we isolated a novel Caenorhabditis elegans active zone gene, clarinet (cla-1). cla-1 mutants exhibit defects in synaptic vesicle clustering, active zone structure and synapse number. As a result, they have reduced spontaneous vesicle release and increased synaptic depression. cla-1 mutants show defects in vesicle distribution near the presynaptic dense projection, with fewer undocked vesicles contacting the dense projection and more docked vesicles at the plasma membrane. cla-1 encodes three isoforms containing common C-terminal PDZ and C2 domains with homology to vertebrate active zone proteins Piccolo and RIM. The C-termini of all isoforms localize to the active zone. Specific loss of the ~9000 amino acid long isoform results in vesicle clustering defects and increased synaptic depression. Our data indicate that specific isoforms of clarinet serve distinct functions, regulating synapse development, vesicle clustering and release. PMID:29160205
Viana, A P; Lucena Frédou, F
2014-05-01
The objective of the present study was to describe the ecological status of ichthyofauna in an industrial district (Pará river, Amazon estuary), through the use of different environmental descriptors. To evaluate the impacts of the industrial area and cargo terminal, three areas were considered: Zone 1 (maximum impact), Zone 2 (median impact) and Zone 3 (low impact). A total of 77 species were captured. Differences in the composition of the ichthyofauna were recorded between Zones and environments (main channel and tidal channel). The ecological indices revealed clear evidence of the impact of the industrial hub and cargo terminal on the fish communities. In Zone 1, there was a reduction in the number of feeding groups (in the main channel) and larger fish and the Shannon diversity index and Margalef's richness were also significantly lower. The multivariate analysis separated the different Zones clearly into three groups, indicating marked differences in the levels of contamination in the different parts of the study area.
7 CFR 25.607 - Suspension or termination of grant funds.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 7 Agriculture 1 2013-01-01 2013-01-01 false Suspension or termination of grant funds. 25.607 Section 25.607 Agriculture Office of the Secretary of Agriculture RURAL EMPOWERMENT ZONES AND ENTERPRISE COMMUNITIES Round II and Round IIS Grants § 25.607 Suspension or termination of grant funds. (a) Grants under...
7 CFR 25.607 - Suspension or termination of grant funds.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 7 Agriculture 1 2012-01-01 2012-01-01 false Suspension or termination of grant funds. 25.607 Section 25.607 Agriculture Office of the Secretary of Agriculture RURAL EMPOWERMENT ZONES AND ENTERPRISE COMMUNITIES Round II and Round IIS Grants § 25.607 Suspension or termination of grant funds. (a) Grants under...
7 CFR 25.607 - Suspension or termination of grant funds.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 7 Agriculture 1 2014-01-01 2014-01-01 false Suspension or termination of grant funds. 25.607 Section 25.607 Agriculture Office of the Secretary of Agriculture RURAL EMPOWERMENT ZONES AND ENTERPRISE COMMUNITIES Round II and Round IIS Grants § 25.607 Suspension or termination of grant funds. (a) Grants under...
7 CFR 25.607 - Suspension or termination of grant funds.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 1 2010-01-01 2010-01-01 false Suspension or termination of grant funds. 25.607 Section 25.607 Agriculture Office of the Secretary of Agriculture RURAL EMPOWERMENT ZONES AND ENTERPRISE COMMUNITIES Round II and Round IIS Grants § 25.607 Suspension or termination of grant funds. (a) Grants under...
7 CFR 25.607 - Suspension or termination of grant funds.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 7 Agriculture 1 2011-01-01 2011-01-01 false Suspension or termination of grant funds. 25.607 Section 25.607 Agriculture Office of the Secretary of Agriculture RURAL EMPOWERMENT ZONES AND ENTERPRISE COMMUNITIES Round II and Round IIS Grants § 25.607 Suspension or termination of grant funds. (a) Grants under...
49 CFR 372.223 - Consolidated governments.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 49 Transportation 5 2012-10-01 2012-10-01 false Consolidated governments. 372.223 Section 372.223... ZONES, AND TERMINAL AREAS Commercial Zones § 372.223 Consolidated governments. The zone adjacent to, and commercially a part of a consolidated government within which transportation by motor vehicle, in interstate or...
49 CFR 372.223 - Consolidated governments.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 5 2010-10-01 2010-10-01 false Consolidated governments. 372.223 Section 372.223... ZONES, AND TERMINAL AREAS Commercial Zones § 372.223 Consolidated governments. The zone adjacent to, and commercially a part of a consolidated government within which transportation by motor vehicle, in interstate or...
49 CFR 372.223 - Consolidated governments.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 49 Transportation 5 2011-10-01 2011-10-01 false Consolidated governments. 372.223 Section 372.223... ZONES, AND TERMINAL AREAS Commercial Zones § 372.223 Consolidated governments. The zone adjacent to, and commercially a part of a consolidated government within which transportation by motor vehicle, in interstate or...
49 CFR 372.223 - Consolidated governments.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 49 Transportation 5 2013-10-01 2013-10-01 false Consolidated governments. 372.223 Section 372.223... ZONES, AND TERMINAL AREAS Commercial Zones § 372.223 Consolidated governments. The zone adjacent to, and commercially a part of a consolidated government within which transportation by motor vehicle, in interstate or...
49 CFR 372.223 - Consolidated governments.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 49 Transportation 5 2014-10-01 2014-10-01 false Consolidated governments. 372.223 Section 372.223... ZONES, AND TERMINAL AREAS Commercial Zones § 372.223 Consolidated governments. The zone adjacent to, and commercially a part of a consolidated government within which transportation by motor vehicle, in interstate or...
49 CFR 372.235 - New York, NY.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 5 2010-10-01 2010-10-01 false New York, NY. 372.235 Section 372.235... ZONES, AND TERMINAL AREAS Commercial Zones § 372.235 New York, NY. The zone adjacent to, and commercially a part of, New York, NY, within which transportation by motor vehicle, in interstate or foreign...
76 FR 70704 - Foreign-Trade Zone 87-Lake Charles, LA; Application for Reorganization/Expansion
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-15
... Charles, LA; Application for Reorganization/Expansion An application has been submitted to the Foreign-Trade Zones Board (the Board) by the Lake Charles Harbor & Terminal District, grantee of FTZ 87, requesting authority to reorganize and expand the zone in Lake Charles. The application was submitted...
78 FR 53426 - Expansion of Foreign-Trade Zone 84; Houston, Texas
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-29
..., and further subject to sunset provisions that would terminate authority on August 31, 2018, for Sites... Commerce for Import Administration, Alternate Chairman, Foreign-Trade Zones Board. ATTEST: Andrew McGilvray...
Cold seeps and splay faults on Nankai margin
NASA Astrophysics Data System (ADS)
Henry, P.; Ashi, J.; Tsunogai, U.; Toki, T.; Kuramoto, S.; Kinoshita, M.; Lallemant, S. J.
2003-04-01
Cold seeps (bacterial mats, specific fauna, authigenic carbonates) are common on the Nankai margin and considered as evidence for seepage of methane bearing fluids. Camera and submersible surveys performed over the years have shown that cold seeps are generally associated with active faults. One question is whether part of the fluids expelled originate from the seismogenic zone and migrate along splay faults to the seafloor. The localisation of most cold seeps on the hanging wall of major thrusts may, however, be interpreted in various ways: (a) footwall compaction and diffuse flow (b) fluid channelling along the fault zone at depths and diffuse flow near the seafloor (c) erosion and channelling along permeable strata. In 2002, new observations and sampling were performed with submersible and ROV (1) on major thrusts along the boundary between the Kumano forearc basin domain and the accretionary wedge domain, (2) on a fault affecting the forearc (Kodaiba fault), (3) on mud volcanoes in the Kumano basin. In area (1) tsunami and seismic inversions indicate that the targeted thrusts are in the slip zone of the To-Nankai 1944 earthquakes. In this area, the largest seep zone, continuous over at least 2 km, coincides with the termination of a thrust trace, indicating local fluid channelling along the edge of the fault zone. Kodaiba fault is part of another splay fault system, which has both thrusting and strike-slip components and terminates westward into an en-echelon fold system. Strong seepage activity with abundant carbonates was found on a fold at the fault termination. One mud volcano, rooted in one of the en-echelon fold, has exceptionally high seepage activity compared with the others and thick carbonate crusts. These observations suggest that fluid expulsion along fault zones is most active at fault terminations and may be enhanced during fault initiation. Preliminary geochemical results indicate signatures differ between seep sites and suggests that the two fault systems tap in different sources.
Hwang, Jeongeun; Kim, Miju; Kim, Seunghwan; Lee, Jinwon
2013-01-01
An effective technique of phase contrast synchrotron radiation computed tomography was established for the quantitative analysis of the microstructures in the respiratory zone of a mouse lung. Heitzman’s method was adopted for the whole-lung sample preparation, and Canny’s edge detector was used for locating the air-tissue boundaries. This technique revealed detailed morphology of the respiratory zone components, including terminal bronchioles and alveolar sacs, with sufficiently high resolution of 1.74 µm isotropic voxel size. The technique enabled visual inspection of the respiratory zone components and comprehension of their relative positions in three dimensions. To check the method’s feasibility for quantitative imaging, morphological parameters such as diameter, surface area and volume were measured and analyzed for sixteen randomly selected terminal branching units, each consisting of a terminal bronchiole and a pair of succeeding alveolar sacs. The four types of asymmetry ratios concerning alveolar sac mouth diameter, alveolar sac surface area, and alveolar sac volume are measured. This is the first ever finding of the asymmetry ratio for the terminal bronchioles and alveolar sacs, and it is noteworthy that an appreciable degree of branching asymmetry was observed among the alveolar sacs at the terminal end of the airway tree, despite the number of samples was small yet. The series of efficient techniques developed and confirmed in this study, from sample preparation to quantification, is expected to contribute to a wider and exacter application of phase contrast synchrotron radiation computed tomography to a variety of studies. PMID:23704918
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-08
... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Docket 43-2011] Foreign-Trade Subzone 38A; Termination of Review of Application for Expansion; BMW Manufacturing Co., LLC (Motor Vehicles); Greer, South Carolina Notice is hereby given of termination of review of an application submitted by the South Carolina State Ports Authority, grantee of FTZ...
76 FR 67379 - Importation of Dracaena Plants From Costa Rica
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-01
... rooting zone for plants produced by air layering) to the farthest terminal growing point. Paragraph (y)(2... the soil line (or top of the rooting zone for plants produced by air layering) to the farthest...
Invaginating Structures in Mammalian Synapses
Petralia, Ronald S.; Wang, Ya-Xian; Mattson, Mark P.; Yao, Pamela J.
2018-01-01
Invaginating structures at chemical synapses in the mammalian nervous system exist in presynaptic axon terminals, postsynaptic spines or dendrites, and glial processes. These invaginating structures can be divided into three categories. The first category includes slender protrusions invaginating into axonal terminals, postsynaptic spines, or glial processes. Best known examples of this category are spinules extending from postsynaptic spines into presynaptic terminals in forebrain synapses. Another example of this category are protrusions from inhibitory presynaptic terminals invaginating into postsynaptic neuronal somas. Regardless of the direction and location, the invaginating structures of the first category do not have synaptic active zones within the invagination. The second category includes postsynaptic spines invaginating into presynaptic terminals, whereas the third category includes presynaptic terminals invaginating into postsynaptic spines or dendrites. Unlike the first category, the second and third categories have active zones within the invagination. An example of the second category are mossy terminal synapses of the hippocampal CA3 region, in which enlarged spine-like structures invaginate partly or entirely into mossy terminals. An example of the third category is the neuromuscular junction (NMJ) where substantial invaginations of the presynaptic terminals invaginate into the muscle fibers. In the retina, rod and cone synapses have invaginating processes from horizontal and bipolar cells. Because horizontal cells act both as post and presynaptic structures, their invaginating processes represent both the second and third category. These invaginating structures likely play broad yet specialized roles in modulating neuronal cell signaling. PMID:29674962
33 CFR 165.1708 - Tongass Narrows, Ketchikan, Alaska-Safety Zone.
Code of Federal Regulations, 2010 CFR
2010-07-01
...°39′40″ W used to conduct fireworks displays. (b) Effective date. The safety zone becomes effective on July 3 each year at 10 p.m. ADT. It terminates at the conclusion of the fireworks display at... fireworks display is postponed because of inclement weather, the date and duration of the safety zone will...
15 CFR 923.81 - Requests for amendments.
Code of Federal Regulations, 2010 CFR
2010-01-01
...) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT COASTAL ZONE MANAGEMENT PROGRAM REGULATIONS Amendments to and Termination of Approved Management... and appropriate, including a discussion of the following factors, as relevant; changes in coastal zone...
15 CFR 923.81 - Requests for amendments.
Code of Federal Regulations, 2011 CFR
2011-01-01
...) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT COASTAL ZONE MANAGEMENT PROGRAM REGULATIONS Amendments to and Termination of Approved Management... and appropriate, including a discussion of the following factors, as relevant; changes in coastal zone...
Code of Federal Regulations, 2011 CFR
2011-07-01
... the Military Ocean Terminal, Bay Area, Pier No. 8 (Port of Oakland Berth No. 10); restricted area. 334..., DEPARTMENT OF DEFENSE DANGER ZONE AND RESTRICTED AREA REGULATIONS § 334.1050 Oakland Outer Harbor adjacent to the Military Ocean Terminal, Bay Area, Pier No. 8 (Port of Oakland Berth No. 10); restricted area. (a...
Code of Federal Regulations, 2014 CFR
2014-07-01
... the Military Ocean Terminal, Bay Area, Pier No. 8 (Port of Oakland Berth No. 10); restricted area. 334..., DEPARTMENT OF DEFENSE DANGER ZONE AND RESTRICTED AREA REGULATIONS § 334.1050 Oakland Outer Harbor adjacent to the Military Ocean Terminal, Bay Area, Pier No. 8 (Port of Oakland Berth No. 10); restricted area. (a...
Code of Federal Regulations, 2010 CFR
2010-07-01
... the Military Ocean Terminal, Bay Area, Pier No. 8 (Port of Oakland Berth No. 10); restricted area. 334..., DEPARTMENT OF DEFENSE DANGER ZONE AND RESTRICTED AREA REGULATIONS § 334.1050 Oakland Outer Harbor adjacent to the Military Ocean Terminal, Bay Area, Pier No. 8 (Port of Oakland Berth No. 10); restricted area. (a...
Code of Federal Regulations, 2012 CFR
2012-07-01
... the Military Ocean Terminal, Bay Area, Pier No. 8 (Port of Oakland Berth No. 10); restricted area. 334..., DEPARTMENT OF DEFENSE DANGER ZONE AND RESTRICTED AREA REGULATIONS § 334.1050 Oakland Outer Harbor adjacent to the Military Ocean Terminal, Bay Area, Pier No. 8 (Port of Oakland Berth No. 10); restricted area. (a...
Code of Federal Regulations, 2013 CFR
2013-07-01
... the Military Ocean Terminal, Bay Area, Pier No. 8 (Port of Oakland Berth No. 10); restricted area. 334..., DEPARTMENT OF DEFENSE DANGER ZONE AND RESTRICTED AREA REGULATIONS § 334.1050 Oakland Outer Harbor adjacent to the Military Ocean Terminal, Bay Area, Pier No. 8 (Port of Oakland Berth No. 10); restricted area. (a...
EHF (28/19 GHz) personal communications satellite terminal development
NASA Technical Reports Server (NTRS)
Pike, Corey
1991-01-01
The concept of communicating on a personal basis using a small terminal has been investigated globally from many different applications and technology perspectives. Applications range from terrestrial handheld communicators for paging, cellular, zone voice/data networks, etc., to satellite terminals of pocket dimensions for voice/low speed data or similar terminals using larger antennas for VSAT, news gathering (30 cm), and video (1.2 m). A brief status of some developments in the satellite personal communications at CRC will be presented.
NASA Technical Reports Server (NTRS)
Fernandez, C.; Lysakowski, A.; Goldberg, J. M.
1995-01-01
1. The numbers of type I and type II hair cells were estimated by dissector techniques applied to semithin, stained sections of the horizontal, superior, and posterior cristae in the squirrel monkey and the chinchilla. 2. The crista in each species was divided into concentrically arranged central, intermediate, and peripheral zones of equal areas. The three zones can be distinguished by the sizes of individual hair cells and calyx endings, by the density of hair cells, and by the relative frequency of calyx endings innervating single or multiple type I hair cells. 3. In the monkey crista, type I hair cells outnumber type II hair cells by a ratio of almost 3:1. The ratio decreases from 4-5:1 in the central and intermediate zones to under 2:1 in the peripheral zone. For the chinchilla, the ratio is near 1:1 for the entire crista and decreases only slightly between the central and peripheral zones. 4. Nerve fibers supplying the cristae in the squirrel monkey were labeled by extracellular injections of horseradish peroxidase (HRP) into the vestibular nerve. Peripheral terminations of individual fibers were reconstructed and related to the zones of the cristae they innervated and to the sizes of their parent axons. Results were similar for the horizontal, superior, and posterior cristae. 5. Axons seldom bifurcate below the neuroepithelium. Most fibers begin branching shortly after crossing the basement membrane. Their terminal arbors are compact, usually extending no more than 50-100 microns from the parent exon. A small number of long intraepithelial fibers enter the intermediate and peripheral zones of the cristae near its base, then run unbranched for long distances through the neuroepithelium to reach the central zone. 6. There are three classes of afferent fibers innervating the monkey crista. Calyx fibers terminate exclusively on type I hair cells, and bouton fibers end only on type II hair cells. Dimorphic fibers provide a mixed innervation, including calyx endings to type I hair cells and bouton endings to type II hair cells. Long intraepithelial fibers are calyx and dimorphic units, whose terminal fields are similar to those of other fibers. The central zone is innervated by calyx and dimorphic fibers; the peripheral zone, by bouton and dimorphic fibers; and the intermediate zone, by all three kinds of fibers. Internal (axon) diameters are largest for calyx fibers and smallest for bouton fibers. Of the entire sample of 286 labeled fibers, 52% were dimorphic units, 40% were calyx units, and 8% were bouton units.(ABSTRACT TRUNCATED AT 400 WORDS).
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-27
... magnet sites; Whereas, notice inviting public comment was given in the Federal Register (76 FR 30906, 05...-purpose zone project, and to a five-year ASF sunset provision for magnet sites that would terminate...
Method of making high breakdown voltage semiconductor device
Arthur, Stephen D.; Temple, Victor A. K.
1990-01-01
A semiconductor device having at least one P-N junction and a multiple-zone junction termination extension (JTE) region which uniformly merges with the reverse blocking junction is disclosed. The blocking junction is graded into multiple zones of lower concentration dopant adjacent termination to facilitate merging of the JTE to the blocking junction and placing of the JTE at or near the high field point of the blocking junction. Preferably, the JTE region substantially overlaps the graded blocking junction region. A novel device fabrication method is also provided which eliminates the prior art step of separately diffusing the JTE region.
Presynaptic Active Zone Density during Development and Synaptic Plasticity.
Clarke, Gwenaëlle L; Chen, Jie; Nishimune, Hiroshi
2012-01-01
Neural circuits transmit information through synapses, and the efficiency of synaptic transmission is closely related to the density of presynaptic active zones, where synaptic vesicles are released. The goal of this review is to highlight recent insights into the molecular mechanisms that control the number of active zones per presynaptic terminal (active zone density) during developmental and stimulus-dependent changes in synaptic efficacy. At the neuromuscular junctions (NMJs), the active zone density is preserved across species, remains constant during development, and is the same between synapses with different activities. However, the NMJ active zones are not always stable, as exemplified by the change in active zone density during acute experimental manipulation or as a result of aging. Therefore, a mechanism must exist to maintain its density. In the central nervous system (CNS), active zones have restricted maximal size, exist in multiple numbers in larger presynaptic terminals, and maintain a constant density during development. These findings suggest that active zone density in the CNS is also controlled. However, in contrast to the NMJ, active zone density in the CNS can also be increased, as observed in hippocampal synapses in response to synaptic plasticity. Although the numbers of known active zone proteins and protein interactions have increased, less is known about the mechanism that controls the number or spacing of active zones. The following molecules are known to control active zone density and will be discussed herein: extracellular matrix laminins and voltage-dependent calcium channels, amyloid precursor proteins, the small GTPase Rab3, an endocytosis mechanism including synaptojanin, cytoskeleton protein spectrins and β-adducin, and a presynaptic web including spectrins. The molecular mechanisms that organize the active zone density are just beginning to be elucidated.
Presynaptic Active Zone Density during Development and Synaptic Plasticity
Clarke, Gwenaëlle L.; Chen, Jie; Nishimune, Hiroshi
2012-01-01
Neural circuits transmit information through synapses, and the efficiency of synaptic transmission is closely related to the density of presynaptic active zones, where synaptic vesicles are released. The goal of this review is to highlight recent insights into the molecular mechanisms that control the number of active zones per presynaptic terminal (active zone density) during developmental and stimulus-dependent changes in synaptic efficacy. At the neuromuscular junctions (NMJs), the active zone density is preserved across species, remains constant during development, and is the same between synapses with different activities. However, the NMJ active zones are not always stable, as exemplified by the change in active zone density during acute experimental manipulation or as a result of aging. Therefore, a mechanism must exist to maintain its density. In the central nervous system (CNS), active zones have restricted maximal size, exist in multiple numbers in larger presynaptic terminals, and maintain a constant density during development. These findings suggest that active zone density in the CNS is also controlled. However, in contrast to the NMJ, active zone density in the CNS can also be increased, as observed in hippocampal synapses in response to synaptic plasticity. Although the numbers of known active zone proteins and protein interactions have increased, less is known about the mechanism that controls the number or spacing of active zones. The following molecules are known to control active zone density and will be discussed herein: extracellular matrix laminins and voltage-dependent calcium channels, amyloid precursor proteins, the small GTPase Rab3, an endocytosis mechanism including synaptojanin, cytoskeleton protein spectrins and β-adducin, and a presynaptic web including spectrins. The molecular mechanisms that organize the active zone density are just beginning to be elucidated. PMID:22438837
Code of Federal Regulations, 2013 CFR
2013-10-01
... 49 Transportation 5 2013-10-01 2013-10-01 false Twin Cities. 372.221 Section 372.221 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY... ZONES, AND TERMINAL AREAS Commercial Zones § 372.221 Twin Cities. For the purpose of determining...
Code of Federal Regulations, 2012 CFR
2012-10-01
... 49 Transportation 5 2012-10-01 2012-10-01 false Twin Cities. 372.221 Section 372.221 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY... ZONES, AND TERMINAL AREAS Commercial Zones § 372.221 Twin Cities. For the purpose of determining...
Code of Federal Regulations, 2014 CFR
2014-10-01
... 49 Transportation 5 2014-10-01 2014-10-01 false Twin Cities. 372.221 Section 372.221 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY... ZONES, AND TERMINAL AREAS Commercial Zones § 372.221 Twin Cities. For the purpose of determining...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-18
... and 2 would be categorized as magnet sites, and the grantee proposes an initial usage-driven site... the zone, to a five-year ASF sunset provision for magnet sites that would terminate authority for...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-04
... be categorized as magnet sites; Whereas, notice inviting public comment has been given in the Federal...-purpose zone project, and to an ASF sunset provision for magnet sites that would terminate authority for...
78 FR 52759 - Expansion of Foreign-Trade Zone 75 Under Alternative Site Framework; Phoenix, Arizona
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-26
..., docketed 12-07-2012) for authority to expand the zone under the ASF to include an additional magnet site...-year ASF sunset provision for magnet sites that would terminate authority for Site 9 if not activated...
The effect of potassium on exocytosis of transmitter at the frog neuromuscular junction.
Ceccarelli, B; Fesce, R; Grohovaz, F; Haimann, C
1988-01-01
1. Electrophysiology and morphology have been combined to investigate the time course of the exocytosis of quanta of neurotransmitter induced by elevated concentrations of K+ at the frog neuromuscular junction. 2. Replicas of freeze-fractured resting nerve terminals fixed in the presence of 20 mM-K+ showed images of fusion of synaptic vesicles with the presynaptic axolemma which were closely associated with the active zones. After 1 min in 20 nM-K+ fusions appeared also outside the active zones, and by 5 min they became uniformly distributed over the presynaptic membrane. 3. The average total density of fusions was not significantly different at the various times examined since it decreased at the active zones while it increased over the rest of the membrane. 4. Resting terminals fixed in 20 mM-K+ released 33,000-45,000 quanta after the addition of fixative; terminals stimulated by 20 mM-K+ for 1-5 min released 50,000-100,000 quanta during fixation. The fixative potentiated K+-induced transmitter release. 5. Fusions were uniformly distributed in terminals pre-incubated for 5 min in 20 mM-K+ without added Ca2+, stimulated by adding Ca2+ for 30 s, and then fixed. Conversely, after 5 min stimulation in hypertonic Ringer solution fusions remained predominantly located near the active zones. A similar distribution was observed after 15 min stimulation by a lower concentration of K+ (15 mM). 6. At all concentrations of K+ tested (10, 15, 20, 25 mM) miniature end-plate potential (MEPP) rate attained a steady-state value within 10-15 min. Values from a single junction were generally lower at higher concentrations of K+, which indicates partial inactivation of the secretion-recycling process. 7. The data indicate that K+ initially activates exocytosis at the active zones. Subsequently, ectopic exocytosis is activated while sites at the active zones appear to undergo partial inactivation. These phenomena are not related to the intensity or to the amount of previous secretion. Images Fig. 1 Fig. 2 Fig. 3 Fig. 8 Fig. 10 PMID:2902217
Federal Register 2010, 2011, 2012, 2013, 2014
2013-07-05
... new Site 9 would be categorized as magnet sites, and existing Site 7 would be categorized as a usage... for the zone, to a five-year ASF sunset provision for magnet sites that would terminate authority for...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-13
... categorized as magnet sites, Sites 6 and 10 would be reduced in size, existing Site 14 would be categorized as...-purpose zone project, to a five-year ASF sunset provision for magnet sites that would terminate authority...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-15
... existing Sites 1 through 6 would be categorized as magnet sites, and the grantee proposes one initial usage... general-purpose zone project, to a five-year ASF sunset provision for magnet sites that would terminate...
NASA Technical Reports Server (NTRS)
Liggett, M. A. (Principal Investigator); Childs, J. F.
1974-01-01
The author has identified the following significant results. Field reconnaissance and study of geologic literature guided by analysis of ERTS-1 MSS imagery have led to a hypothesis of tectonic control of Miocene volcanism, plutonism, and related mineralization in part of the Basin Range Province of southern Nevada and northwestern Arizona. The easterly trending right-lateral Las Vegas Shear Zone separates two volcanic provinces believed to represent areas of major east-west crustal extension. One volcanic province is aligned along the Colorado River south of the eastern termination of the Las Vegas Shear Zone; the second province is located north of the western termination of the shear zone in southern Nye County, Nevada. Geochronologic, geophysical, and structural evidence suggests that the Las Vegas Shear Zone may have formed in response to crustal extension in the two volcanic provinces in a manner similar to the formation of a ridge-ridge transform fault, as recognized in ocean floor tectonics.
49 CFR 372.300 - Distances and population data.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 49 Transportation 5 2012-10-01 2012-10-01 false Distances and population data. 372.300 Section 372..., COMMERCIAL ZONES, AND TERMINAL AREAS Terminal Areas § 372.300 Distances and population data. In the application of this subpart, distances and population data shall be determined in the same manner as provided...
49 CFR 372.300 - Distances and population data.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 49 Transportation 5 2013-10-01 2013-10-01 false Distances and population data. 372.300 Section 372..., COMMERCIAL ZONES, AND TERMINAL AREAS Terminal Areas § 372.300 Distances and population data. In the application of this subpart, distances and population data shall be determined in the same manner as provided...
49 CFR 372.300 - Distances and population data.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 5 2010-10-01 2010-10-01 false Distances and population data. 372.300 Section 372..., COMMERCIAL ZONES, AND TERMINAL AREAS Terminal Areas § 372.300 Distances and population data. In the application of this subpart, distances and population data shall be determined in the same manner as provided...
49 CFR 372.300 - Distances and population data.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 49 Transportation 5 2014-10-01 2014-10-01 false Distances and population data. 372.300 Section 372..., COMMERCIAL ZONES, AND TERMINAL AREAS Terminal Areas § 372.300 Distances and population data. In the application of this subpart, distances and population data shall be determined in the same manner as provided...
49 CFR 372.300 - Distances and population data.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 49 Transportation 5 2011-10-01 2011-10-01 false Distances and population data. 372.300 Section 372..., COMMERCIAL ZONES, AND TERMINAL AREAS Terminal Areas § 372.300 Distances and population data. In the application of this subpart, distances and population data shall be determined in the same manner as provided...
Code of Federal Regulations, 2011 CFR
2011-10-01
... 49 Transportation 5 2011-10-01 2011-10-01 false Twin Cities. 372.221 Section 372.221... ZONES, AND TERMINAL AREAS Commercial Zones § 372.221 Twin Cities. For the purpose of determining... following combinations of cities shall be considered as a single municipality: (a) Having a population equal...
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 5 2010-10-01 2010-10-01 false Twin Cities. 372.221 Section 372.221... ZONES, AND TERMINAL AREAS Commercial Zones § 372.221 Twin Cities. For the purpose of determining... following combinations of cities shall be considered as a single municipality: (a) Having a population equal...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-12
..., 3, and 4 would be categorized as magnet sites, and FTZ 93's existing Site 2 would be categorized as... the zone, to a five-year ASF sunset provision for magnet sites that would terminate authority for Site...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-07
... Protection port of entry, FTZ 43's existing Site 1 would be categorized as a magnet site and existing Site 8... limit for the zone, to a five-year ASF sunset provision for magnet sites that would terminate authority...
40 CFR 205.54-1 - Low speed sound emission test procedures.
Code of Federal Regulations, 2013 CFR
2013-07-01
... beyond the permissible end zone, unload the vehicle and/or increase the approach rpm in 100 rpm... rpm beyond the permissible end zone, unload the vehicle and/or increase the approach rpm in 100 rpm... example, temperature, humidity, and barometric pressure). (ii) Proper signal levels, terminat-ing...
77 FR 54891 - Reorganization of Foreign-Trade Zone 149 Under Alternative Site Framework Freeport, TX
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-06
... 1, 3 and 10 would be categorized as magnet sites, and FTZ 149's Sites 2, 4, 5, 6, 7, 8, 9, 11 and 12... limit for the zone, and to a five-year ASF sunset provision for magnet sites that would terminate...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-03
... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Order No. 1728] Voluntary Termination of Foreign-Trade Subzone 102A, Ford Motor Corporation, Hazelwood, MO Pursuant to the authority granted in the... the Ford Motor Corporation plant in Hazelwood, Missouri (Board Order 252, 49 FR 19541, 5/8/84...
33 CFR 165.T0704 - Safety Zone: Savannah River, Savannah, Georgia.
Code of Federal Regulations, 2014 CFR
2014-07-01
...: Two hundred foot radius around Garden City Terminal, approximate position 32 degrees 8 minutes, N, 81... terminated by the Captain of the Port, Savannah, GA. (c) Regulation. In accordance with the general... the Captain of the Port, Savannah, GA to act on his behalf. A representative of the Captain of the...
33 CFR 165.T0704 - Safety Zone: Savannah River, Savannah, Georgia.
Code of Federal Regulations, 2012 CFR
2012-07-01
...: Two hundred foot radius around Garden City Terminal, approximate position 32 degrees 8 minutes, N, 81... terminated by the Captain of the Port, Savannah, GA. (c) Regulation. In accordance with the general... the Captain of the Port, Savannah, GA to act on his behalf. A representative of the Captain of the...
33 CFR 165.T0704 - Safety Zone: Savannah River, Savannah, Georgia.
Code of Federal Regulations, 2013 CFR
2013-07-01
...: Two hundred foot radius around Garden City Terminal, approximate position 32 degrees 8 minutes, N, 81... terminated by the Captain of the Port, Savannah, GA. (c) Regulation. In accordance with the general... the Captain of the Port, Savannah, GA to act on his behalf. A representative of the Captain of the...
33 CFR 165.T0704 - Safety Zone: Savannah River, Savannah, Georgia.
Code of Federal Regulations, 2011 CFR
2011-07-01
...: Two hundred foot radius around Garden City Terminal, approximate position 32 degrees 8 minutes, N, 81... terminated by the Captain of the Port, Savannah, GA. (c) Regulation. In accordance with the general... the Captain of the Port, Savannah, GA to act on his behalf. A representative of the Captain of the...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-17
... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Docket 44-2010] Termination of Review of Sourcing Change, Foreign-Trade Subzone 61H, Baxter Healthcare of Puerto Rico, (Inhalation Anesthetics... chemical ingredients at the manufacturing facility of Baxter Healthcare of Puerto Rico located in Guayama...
Fault evolution in the Potiguar rift termination, equatorial margin of Brazil
NASA Astrophysics Data System (ADS)
de Castro, D. L.; Bezerra, F. H. R.
2015-02-01
The transform shearing between South American and African plates in the Cretaceous generated a series of sedimentary basins on both plate margins. In this study, we use gravity, aeromagnetic, and resistivity surveys to identify architecture of fault systems and to analyze the evolution of the eastern equatorial margin of Brazil. Our study area is the southern onshore termination of the Potiguar rift, which is an aborted NE-trending rift arm developed during the breakup of Pangea. The basin is located along the NNE margin of South America that faces the main transform zone that separates the North and the South Atlantic. The Potiguar rift is a Neocomian structure located at the intersection of the equatorial and western South Atlantic and is composed of a series of NE-trending horsts and grabens. This study reveals new grabens in the Potiguar rift and indicates that stretching in the southern rift termination created a WNW-trending, 10 km wide, and ~ 40 km long right-lateral strike-slip fault zone. This zone encompasses at least eight depocenters, which are bounded by a left-stepping, en echelon system of NW-SE- to NS-striking normal faults. These depocenters form grabens up to 1200 m deep with a rhomb-shaped geometry, which are filled with rift sedimentary units and capped by postrift sedimentary sequences. The evolution of the rift termination is consistent with the right-lateral shearing of the equatorial margin in the Cretaceous and occurs not only at the rift termination but also as isolated structures away from the main rift. This study indicates that the strike-slip shearing between two plates propagated to the interior of one of these plates, where faults with similar orientation, kinematics, geometry, and timing of the major transform are observed. These faults also influence rift geometry.
Static stress change from the 8 October, 2005 M = 7.6 Kashmir earthquake
Parsons, T.; Yeats, R.S.; Yagi, Y.; Hussain, A.
2006-01-01
We calculated static stress changes from the devastating M = 7.6 earthquake that shook Kashmir on 8 October, 2005. We mapped Coulomb stress change on target fault planes oriented by assuming a regional compressional stress regime with greatest principal stress directed orthogonally to the mainshock strike. We tested calculation sensitivity by varying assumed stress orientations, target-fault friction, and depth. Our results showed no impact on the active Salt Range thrust southwest of the rupture. Active faults north of the Main Boundary thrust near Peshawar fall in a calculated stress-decreased zone, as does the Raikot fault zone to the northeast. We calculated increased stress near the rupture where most aftershocks occurred. The greatest increase to seismic hazard is in the Indus-Kohistan seismic zone near the Indus River northwest of the rupture termination, and southeast of the rupture termination near the Kashmir basin.
33 CFR 165.1156 - Safety Zone; Offshore Marine Terminal, El Segundo, CA.
Code of Federal Regulations, 2010 CFR
2010-07-01
... area of the safety zone may contact the Captain of the Port at telephone number 1-800-221-8724 or on... OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION AREAS AND LIMITED ACCESS AREAS Specific Regulated Navigation Areas and Limited Access Areas Eleventh Coast Guard District...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-19
... security zones as RNAs. The Marine Air Terminal, United Nations, and United Nations West Channel Closure... United Nations General Assembly RNA Regulated Navigation Area UN United Nations A. Public Participation... comment, it will be considered as having been received by the Coast Guard when it is received at the...
Philip A. Marcus; Ethan T. Smith
1979-01-01
Five petroleum-related facilities often sited in the coastal zone during development of Outer Continental oil and gas can change the visual appearance of coastal areas. These facilities are service bases, platform fabrication yards, marine terminals and associated storage facilities, oil and gas processing facilities, and liquified natural gas terminals. Examples of...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-25
... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Order No. 1799] Voluntary Termination of Foreign-Trade Subzone 90A Smith Corona Corporation, Cortland County, New York Pursuant to the authority granted... Smith Corona Corporation plant in Cortland County, New York (Board Order 300, 50 FR 15469, 04/18/85...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-27
... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Order No. 1802] Voluntary Termination of Foreign-Trade Subzone 84S Academy Sports and Outdoors, Katy and Brookshire, TX Pursuant to the authority granted... at the Academy Sports and Outdoors facilities in Katy and Brookshire, Texas (Board Order 1511, 72 FR...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-27
... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Order No. 1829] Voluntary Termination of Foreign-Trade Subzone 33B Verosol USA, Inc. Kennedy Township, Allegheny County, PA Pursuant to the authority... the establishment of Foreign-Trade Subzone 33B at the Verosol USA, Inc., plant in Kennedy Township...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-22
... categorized as magnet sites, and the grantee proposes an additional magnet site (Site 29); Whereas, notice...-year ASF sunset provision for magnet sites that would terminate authority for Sites 3-5, 8, 10, 11, 14... for magnet sites that would terminate authority for Sites 6, 9, 12, 13, 22 and 24 if not activated by...
33 CFR 165.703 - Tampa Bay, Florida-Safety Zone.
Code of Federal Regulations, 2013 CFR
2013-07-01
... loaded anhydrous ammonia vessel and the width of the channel in the following areas: (1) For inbound tank vessels loaded with anhydrous ammonia, Tampa Bay Cut “F” Channel from Lighted Buoys “3F” and “4F” north... anhydrous ammonia receiving terminals to Port Sutton the safety zone includes, in addition to the area in...
33 CFR 165.703 - Tampa Bay, Florida-Safety Zone.
Code of Federal Regulations, 2014 CFR
2014-07-01
... loaded anhydrous ammonia vessel and the width of the channel in the following areas: (1) For inbound tank vessels loaded with anhydrous ammonia, Tampa Bay Cut “F” Channel from Lighted Buoys “3F” and “4F” north... anhydrous ammonia receiving terminals to Port Sutton the safety zone includes, in addition to the area in...
33 CFR 165.703 - Tampa Bay, Florida-Safety Zone.
Code of Federal Regulations, 2011 CFR
2011-07-01
... loaded anhydrous ammonia vessel and the width of the channel in the following areas: (1) For inbound tank vessels loaded with anhydrous ammonia, Tampa Bay Cut “F” Channel from Lighted Buoys “3F” and “4F” north... anhydrous ammonia receiving terminals to Port Sutton the safety zone includes, in addition to the area in...
33 CFR 165.703 - Tampa Bay, Florida-Safety Zone.
Code of Federal Regulations, 2012 CFR
2012-07-01
... loaded anhydrous ammonia vessel and the width of the channel in the following areas: (1) For inbound tank vessels loaded with anhydrous ammonia, Tampa Bay Cut “F” Channel from Lighted Buoys “3F” and “4F” north... anhydrous ammonia receiving terminals to Port Sutton the safety zone includes, in addition to the area in...
33 CFR 165.703 - Tampa Bay, Florida-Safety Zone.
Code of Federal Regulations, 2010 CFR
2010-07-01
... loaded anhydrous ammonia vessel and the width of the channel in the following areas: (1) For inbound tank vessels loaded with anhydrous ammonia, Tampa Bay Cut “F” Channel from Lighted Buoys “3F” and “4F” north... anhydrous ammonia receiving terminals to Port Sutton the safety zone includes, in addition to the area in...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-12
... [Order No. 1817] Reorganization/Expansion of Foreign-Trade Zone 77 Under Alternative Site Framework... project, to a five-year ASF sunset provision for magnet sites that would terminate authority for Site 4 if not activated by February 28, 2017, and to a three-year ASF sunset provision for usage-driven sites...
15 CFR 923.84 - Routine program changes.
Code of Federal Regulations, 2010 CFR
2010-01-01
...) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT COASTAL ZONE MANAGEMENT PROGRAM REGULATIONS Amendments to and Termination of Approved Management...
15 CFR 923.84 - Routine program changes.
Code of Federal Regulations, 2011 CFR
2011-01-01
...) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT COASTAL ZONE MANAGEMENT PROGRAM REGULATIONS Amendments to and Termination of Approved Management...
NASA Astrophysics Data System (ADS)
Heusser, L. E.; Hendy, I. L.
2015-12-01
The Younger Dryas is a well-known rapid climatic cooling that interrupted the Marine Isotope Stage (MIS) 1-2 deglacial warming of Termination 1. This cool event has been associated with ice sheet readvance, meridional overturning, circulation changes, and southward movement of the Intertropical Convergence Zone. In Southern California, the Younger Dryas has been associated with cooler SST, low marine productivity, a well-ventilated oxygen minimum zone, and a wetter climate. Similar rapid cooling events have been found at other terminations including Termination 5 at the MIS 11-12 deglaciation (~425 Ka) identified by ice rafting events in the North Atlantic. Here we present new pollen census data from a unique suite of cores taken from the sub-oxic sediments of Santa Barbara Basin (MV0508-15JC, MV0805-20JC, MV0508-33JC, 29JC and 21JC). These short cores, collected on a truncated anticline within SBB, provide the opportunity to examine the response of southern California terrestrial and marine ecosystems to rapid climate change during the MIS 11-12 deglaciation (Termination 5), which is identified by a bioturbated interval within a sequence of laminated sediments. During Termination 1, changes in Southern California precipitation are reflected in pollen- based reconstructions Southern California vegetation. The high precipitation of glacial montane-coniferous assemblages of pine (Pinus) and Juniper (Juniperus/Calocedrus) transitions into interglacial drought, as expresssed by arid oak (Quercus)/chaparral vegetation. The Younger Dryas interrupts the transition as a high-amplitude pulse in pine associated with increased Gramineae (grass). Termination 5 differs, as the high precipitation of glacial montane-coniferous assemblages do not transition into arid oak/chaparral vegetation. However, a Younger Dryas-like rapid climate event was associated with increased pine and grass.
15 CFR 923.82 - Amendment review/approval procedures.
Code of Federal Regulations, 2011 CFR
2011-01-01
... (Continued) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT COASTAL ZONE MANAGEMENT PROGRAM REGULATIONS Amendments to and Termination of Approved...
15 CFR 923.82 - Amendment review/approval procedures.
Code of Federal Regulations, 2010 CFR
2010-01-01
... (Continued) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT COASTAL ZONE MANAGEMENT PROGRAM REGULATIONS Amendments to and Termination of Approved...
77 FR 44472 - Safety Zone; Port Valdez, Alaska Maritime Highway System Ferry Terminal
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-30
... Game, which does not afford time for public feedback on a safety zone that will be in effect only when... month of July, the Alaska Department of Fish and Game has announced fishing openers in the Port of... an Alaska Department of Fish and Game fish opener that includes the 200-yard radius surrounding the...
[Study of the intracerebral connections after intracortical administration of glutamate].
Otellin, V A; Rybakov, V L; Grigor'ev, I P
1980-10-01
Various microdoses of monosubstituted sodium L-glutamate (MSG) were injected into zone AI of the cat cerebral acoustic cortex. In 2 h--14 days, it was stated light optically that the place of injection was slightly stained, and most of neurons failed to stain. At the place of MSG injection, electron microscopic investigation revealed neurons with various degree of pathologic changes up to the lethal ones. Astroglia was edematous, oligodendrocytes and pericytes had normal appearance. In field 4 and in zone AII of the acoustic cortex, separate neural cells with sharply increasing number of ribosomes and polysomes were noted. Anterograde axonal degeneration in the lesioned neurons and their terminals was revealed in frontal sections impregnated after Wiitanen. In the cortical field 7, in zones AII, AIV, Ep of the acoustic cortex, in the head of the nucleus caudatus and in the internal geniculate body, terminal boutons degenerating after the dark type and at the same time as after surgical extirpation of zone AI were revealed. Owing to the fact that the lesions are of local character and the trauma is small, it is possible to use neuronal glutamate-induced degeneration as a method for investigating intracerebral connections.
Reproduction in the male honey possum (Tarsipes rostratus: Marsupialia): the epididymis.
Cummins, J M; Temple-Smith, P D; Renfree, M B
1986-11-01
The epididymis of the adult honey possum, Tarsipes rostratus, is enclosed by a heavily pigmented tunica vaginalis and lies with the testis in a prominent prepenile scrotum. It is connected to the testis by a single ductus efferentis and is lined by approximately equal numbers of cuboidal ciliated and principal cells. It is unusual for marsupials in having no well-defined compartments or fibrous septae and in having extensive convolutions of the duct only at the caudal flexure. Three principal functional zones (initial, middle, and terminal segments) were identified in the epididymis, based on epithelial type and ultrastructural evidence of sperm maturation. Luminal diameter increases progressively throughout the tract, and epithelial height variations (from about 2 to 20 microns) are greatest in the terminal segment. The epithelium itself is remarkably low (maximum of 21.6 microns) compared with that seen in the epididymis of other mammals. The thickness of the peritubular smooth muscle coat increases close to the junction of the epididymis and ductus deferens. Sperm concentrations were estimated from counts of sperm nuclei and thus can be no more than approximations. The figures are consistent, however, with a rapid increase in concentration in the initial segment, indicating extensive fluid resorption. Sperm concentrations appear to peak in the distal zone of the terminal segment, although sampling problems and wide variations in count make such a conclusion only tentative. Principal and basal cells are the predominant cell types in the epididymal epithelium. Basal cells are most abundant in the initial and distal middle segment. Principal cells show structural evidence of active exchange with the luminal contents and have abundant apical stereocilia, the structure of which depends on the epididymal zone. Other cell types occur less commonly in the epithelium. Lipid-rich and phagocytic principal cells are restricted to the middle and distal zones of the middle segment, respectively. Clear cells, restricted to the terminal segment, and halo cells were found in very low numbers. As in some other marsupials, principal cells (possibly specialized for this function) selectively remove cytoplasmic droplets and probably other cellular debris from the luminal contents. In Tarsipes, however, this process is not very efficient, and many discarded droplets pass through to the terminal segment where they form large masses of debris associated with aggregates of degenerating spermatozoa.
Ma, Bai-Wei; Zhao, Xin-Cheng; Berg, Bente G.; Xie, Gui-Ying; Tang, Qing-Bo; Wang, Gui-Rong
2017-01-01
The oriental armyworm, Mythimna separata (Walker), is a polyphagous, migratory pest relying on olfactory cues to find mates, locate nectar, and guide long-distance flight behavior. In the present study, a combination of neuroanatomical techniques were utilized on this species, including backfills, confocal microscopy, and three-dimensional reconstructions, to trace the central projections of sensory neurons from the antenna and the labial pit organ, respectively. As previously shown, the axons of the labial sensory neurons project via the ipsilateral labial nerve and terminate in three main areas of the central nervous system: (1) the labial-palp pit organ glomerulus of each antennal lobe, (2) the gnathal ganglion, and (3) the prothoracic ganglion of the ventral nerve cord. Similarly, the antennal sensory axons project to multiple areas of the central nervous system. The ipsilateral antennal nerve targets mainly the antennal lobe, the antennal mechanosensory and motor center, and the prothoracic and mesothoracic ganglia. Specific staining experiments including dye application to each of the three antennal segments indicate that the antennal lobe receives input from flagellar olfactory neurons exclusively, while the antennal mechanosensory and motor center is innervated by mechanosensory neurons from the whole antenna, comprising the flagellum, pedicle, and scape. The terminals in the mechanosensory and motor center are organized in segregated zones relating to the origin of neurons. The flagellar mechanosensory axons target anterior zones, while the pedicular and scapal axons terminate in posterior zones. In the ventral nerve cord, the processes from the antennal sensory neurons terminate in the motor area of the thoracic ganglia, suggesting a close connection with motor neurons. Taken together, the numerous neuropils innervated by axons both from the antenna and labial palp indicate the multiple roles these sensory organs serve in insect behavior. PMID:29209176
Complementary Therapies for Idiopathic Hirsutism: Topical Licorice as Promising Option
Faghihi, Gita; Iraji, Fariba; Abtahi-Naeini, Bahareh; Saffar, Bahar; Saffaei, Ali; Pourazizi, Mohsen; Aslani, Abolfazl; Nilforoushzadeh, Mohammad Ali
2015-01-01
Hirsutism is one of the most prevalent health problems in women. The aim of the study was to compare the effect of 755 nm alexandrite hair removal laser with that of alexandrite laser plus topical licorice on the improvement of idiopathic hirsutism. A double-blind, randomized placebo-controlled study was performed on 90 female subjects. The patients were divided into two groups: alexandrite laser plus 15% licorice gel (group A) and placebo (group B). Each subject received one of both products over one side of the face, twice daily for 24 weeks on the hirsute locations. Each group underwent five sessions of alexandrite laser at 6-week intervals. To minimize the effects of confounding variables, the test was performed on two separate zones of patients' skin. The mean ± SD numbers of terminal hairs in group A were 7.05 ± 4.55 for zone 1 and 6.06 ± 3.70 for zone 2. In group B, they were 3.18 ± 1.75 for zone 1 and 2.49 ± 1.63 for zone 2. The difference in the mean number of terminal hairs was statistically significant between the two groups (p < 0.001), and there were no serious adverse reactions. The treatment of idiopathic hirsutism with 755 nm alexandrite laser plus topical licorice is more effective than alexandrite laser only. PMID:26273313
NASA Astrophysics Data System (ADS)
Valle Aguado, B.; Azevedo, M. R.; Nolan, J.; Medina, J.; Costa, M. M.; Corfu, F.; Martínez Catalán, J. R.
2017-05-01
A major event of plutonic activity occurred all across the Central Iberian Zone of the Iberian Variscan Belt at the end of Late Paleozoic Variscan collisional tectonism. The present study focuses on the western sector of the Viseu late-post-tectonic batholith (central Portugal), a large composite intrusion comprising three main plutonic units: (a) small bodies of mafic to intermediate composition preferentially concentrated along the northern border, (b) a wide ring of coarse porphyritic biotite monzogranite (Cota-Viseu granite) and (c) a more evolved medium porphyritic, biotite-muscovite monzogranite occupying the central part of the intrusion (Alcafache granite). The compositional zonation pattern of the whole batholith and the complex mixing/mingling relationships between the voluminous Cota-Viseu porphyritic granite and the mafic/intermediate rocks suggest that these melts were withdrawn from a lower crustal source region undergoing partial melting, invasion by mantle-derived mafic magmas, mixing and fractional crystallization. New CA-ID-TIMS U-Pb zircon ages indicate that pluton assembly via multipulse injection of successive magma batches took place between 299.4 ± 0.4 Ma and 296.0 ± 0.6 Ma. A detailed anisotropy of magnetic susceptibility (AMS) survey suggests that pluton emplacement occurred at the extensional termination of a regional-scale, ENE-WSW trending, sinistral D3 shear zone - the Juzbado-Penalva Shear Zone (JPSZ). A dilational opening model involving the development of "en-échelon" tensional gashes at the extensional termination of the fault, followed by progressive opening and widening of north-south trending fractures, provided the space into which the successive magma batches arriving from below were emplaced. Vertical inflation was accommodated by depression of the pluton floor. The proposed model is consistent with the asymmetric wedge-shaped geometry of the intrusion (steep root zone on the northern side, discordant subvertical walls and a shallowing pluton floor towards the south).
The effect of segmented fault zones on earthquake rupture propagation and termination
NASA Astrophysics Data System (ADS)
Huang, Y.
2017-12-01
A fundamental question in earthquake source physics is what can control the nucleation and termination of an earthquake rupture. Besides stress heterogeneities and variations in frictional properties, damaged fault zones (DFZs) that surround major strike-slip faults can contribute significantly to earthquake rupture propagation. Previous earthquake rupture simulations usually characterize DFZs as several-hundred-meter-wide layers with lower seismic velocities than host rocks, and find earthquake ruptures in DFZs can exhibit slip pulses and oscillating rupture speeds that ultimately enhance high-frequency ground motions. However, real DFZs are more complex than the uniform low-velocity structures, and show along-strike variations of damages that may be correlated with historical earthquake ruptures. These segmented structures can either prohibit or assist rupture propagation and significantly affect the final sizes of earthquakes. For example, recent dense array data recorded at the San Jacinto fault zone suggests the existence of three prominent DFZs across the Anza seismic gap and the south section of the Clark branch, while no prominent DFZs were identified near the ends of the Anza seismic gap. To better understand earthquake rupture in segmented fault zones, we will present dynamic rupture simulations that calculate the time-varying rupture process physically by considering the interactions between fault stresses, fault frictional properties, and material heterogeneities. We will show that whether an earthquake rupture can break through the intact rock outside the DFZ depend on the nucleation size of the earthquake and the rupture propagation distance in the DFZ. Moreover, material properties of the DFZ, stress conditions along the fault, and friction properties of the fault also have a critical impact on rupture propagation and termination. We will also present scenarios of San Jacinto earthquake ruptures and show the parameter space that is favorable for rupture propagation through the Anza seismic gap. Our results suggest that a priori knowledge of properties of segmented fault zones is of great importance for predicting sizes of future large earthquakes on major faults.
The Role of Neurotrophins in Neurotransmitter Release
Tyler, William J.; Perrett, Stephen P.; Pozzo-Miller, Lucas D.
2009-01-01
The neurotrophins (NTs) have recently been shown to elicit pronounced effects on quantal neurotransmitter release at both central and peripheral nervous system synapses. Due to their activity-dependent release, as well as the subcellular localization of both protein and receptor, NTs are ideally suited to modify the strength of neuronal connections by “fine-tuning” synaptic activity through direct actions at presynaptic terminals. Here, using BDNF as a prototypical example, the authors provide an update of recent evidence demonstrating that NTs enhance quantal neurotransmitter release at synapses through presynaptic mechanisms. The authors further propose that a potential target for NT actions at presynaptic terminals is the mechanism by which terminals retrieve synaptic vesicles after exocytosis. Depending on the temporal demands placed on synapses during high-frequency synaptic transmission, synapses may use two alternative modes of synaptic vesicle retrieval, the conventional slow endosomal recycling or a faster rapid retrieval at the active zone, referred to as “kiss-and-run.” By modulating Ca2+ microdomains associated with voltage-gated Ca2+ channels at active zones, NTs may elicit a switch from the slow to the fast mode of endocytosis of vesicles at presynaptic terminals during high-frequency synaptic transmission, allowing more reliable information transfer and neuronal signaling in the central nervous system. PMID:12467374
The role of neurotrophins in neurotransmitter release.
Tyler, William J; Perrett, Stephen P; Pozzo-Miller, Lucas D
2002-12-01
The neurotrophins (NTs) have recently been shown to elicit pronounced effects on quantal neurotransmitter release at both central and peripheral nervous system synapses. Due to their activity-dependent release, as well as the subcellular localization of both protein and receptor, NTs are ideally suited to modify the strength of neuronal connections by "fine-tuning" synaptic activity through direct actions at presynaptic terminals. Here, using BDNF as a prototypical example, the authors provide an update of recent evidence demonstrating that NTs enhance quantal neurotransmitter release at synapses through presynaptic mechanisms. The authors further propose that a potential target for NT actions at presynaptic terminals is the mechanism by which terminals retrieve synaptic vesicles after exocytosis. Depending on the temporal demands placed on synapses during high-frequency synaptic transmission, synapses may use two alternative modes of synaptic vesicle retrieval, the conventional slow endosomal recycling or a faster rapid retrieval at the active zone, referred to as "kiss-and-run." By modulating Ca2+ microdomains associated with voltage-gated Ca2+ channels at active zones, NTs may elicit a switch from the slow to the fast mode of endocytosis of vesicles at presynaptic terminals during high-frequency synaptic transmission, allowing more reliable information transfer and neuronal signaling in the central nervous system.
33 CFR 165.1706 - Gastineau Channel, Juneau, Alaska-Safety Zone.
Code of Federal Regulations, 2010 CFR
2010-07-01
... at 58°17′41″ N, 134°24′22″ W used to conduct fireworks displays. (b) Effective date. The safety zone becomes effective on July 3 each year at 10 p.m. ADT. It terminates at the conclusion of the fireworks... Port. If the fireworks display is postponed because of inclement weather, the date and duration of the...
Coseismic rupturing stopped by Aso volcano during the 2016 Mw 7.1 Kumamoto earthquake, Japan.
Lin, A; Satsukawa, T; Wang, M; Mohammadi Asl, Z; Fueta, R; Nakajima, F
2016-11-18
Field investigations and seismic data show that the 16 April 2016 moment magnitude (M w ) 7.1 Kumamoto earthquake produced a ~40-kilometer-long surface rupture zone along the northeast-southwest-striking Hinagu-Futagawa strike-slip fault zone and newly identified faults on the western side of Aso caldera, Kyushu Island, Japan. The coseismic surface ruptures cut Aso caldera, including two volcanic cones inside it, but terminate therein. The data show that northeastward propagation of coseismic rupturing terminated in Aso caldera because of the presence of magma beneath the Aso volcanic cluster. The seismogenic faults of the 2016 Kumamoto earthquake may require reassessment of the volcanic hazard in the vicinity of Aso volcano. Copyright © 2016, American Association for the Advancement of Science.
Roberts, P A
1979-07-01
The high variability of chromomeric patterns in near-terminal regions of polytene chromosome arms has been explored in a number of races, strains and hybrids of Drosophila melanogaster. Traditional explanations for tip differences between strains (differential compaction of chromatin, somatic or germinal deletion) are examined and, in the light of the reported observations, rejected. The range of polytene tip variability and rates of change in wild races are greater than has been supposed: strains formerly considered to be terminally deleted appear to gain terminal bands; others, formerly considered normal, appear to have lost them. Strains with high cell-to-cell tip variability are also described. Cell-to-cell variations, as well as much of the observed rapid changes in tip appearance, are probably due to heritable differences in the location of an abrupt transition zone between polytene and nonpolytene chromatin. A quantitative relationship between the amount of certain subterminal bands present and the frequency of tip association of nonhomologous chromosomes is shown and its possible significance for chromosome is shown and its possible for chromosome pairing discussed.
Bradley, P.M.; Chapelle, F.H.; Vroblesky, D.A.
1993-01-01
In groundwater from a petroleum hydrocarbon-contaminated aquifer. Substantial accumulation of aliphatic organic acids occurred only in methanogenic microcosms, and only trace amounts of acetic acid were detected in sulfate-reducing microcosms. This pattern parallels field observations in which high organic acid concentrations were detected in methanogenic zones, but only low concentrations of acetic acid were detected in sulfate-reducing zones. -from Authors
Protocol for multiple node network
NASA Technical Reports Server (NTRS)
Kirkham, Harold (Inventor)
1995-01-01
The invention is a multiple interconnected network of intelligent message-repeating remote nodes which employs an antibody recognition message termination process performed by all remote nodes and a remote node polling process performed by other nodes which are master units controlling remote nodes in respective zones of the network assigned to respective master nodes. Each remote node repeats only those messages originated in the local zone, to provide isolation among the master nodes.
Protocol for multiple node network
NASA Technical Reports Server (NTRS)
Kirkham, Harold (Inventor)
1994-01-01
The invention is a multiple interconnected network of intelligent message-repeating remote nodes which employs an antibody recognition message termination process performed by all remote nodes and a remote node polling process performed by other nodes which are master units controlling remote nodes in respective zones of the network assigned to respective master nodes. Each remote node repeats only those messages originated in the local zone, to provide isolation among the master nodes.
The Sorong Fault Zone, Indonesia: Mapping a Fault Zone Offshore
NASA Astrophysics Data System (ADS)
Melia, S.; Hall, R.
2017-12-01
The Sorong Fault Zone is a left-lateral strike-slip fault zone in eastern Indonesia, extending westwards from the Bird's Head peninsula of West Papua towards Sulawesi. It is the result of interactions between the Pacific, Caroline, Philippine Sea, and Australian Plates and much of it is offshore. Previous research on the fault zone has been limited by the low resolution of available data offshore, leading to debates over the extent, location, and timing of movements, and the tectonic evolution of eastern Indonesia. Different studies have shown it north of the Sula Islands, truncated south of Halmahera, continuing to Sulawesi, or splaying into a horsetail fan of smaller faults. Recently acquired high resolution multibeam bathymetry of the seafloor (with a resolution of 15-25 meters), and 2D seismic lines, provide the opportunity to trace the fault offshore. The position of different strands can be identified. On land, SRTM topography shows that in the northern Bird's Head the fault zone is characterised by closely spaced E-W trending faults. NW of the Bird's Head offshore there is a fold and thrust belt which terminates some strands. To the west of the Bird's Head offshore the fault zone diverges into multiple strands trending ENE-WSW. Regions of Riedel shearing are evident west of the Bird's Head, indicating sinistral strike-slip motion. Further west, the ENE-WSW trending faults turn to an E-W trend and there are at least three fault zones situated immediately south of Halmahera, north of the Sula Islands, and between the islands of Sanana and Mangole where the fault system terminates in horsetail strands. South of the Sula islands some former normal faults at the continent-ocean boundary with the North Banda Sea are being reactivated as strike-slip faults. The fault zone does not currently reach Sulawesi. The new fault map differs from previous interpretations concerning the location, age and significance of different parts of the Sorong Fault Zone. Kinematic analysis is underway to give a fresh understanding of the tectonic evolution of this complex zone of faulting and plate interaction.
Hirota, Yuki; Kubo, Ken-Ichiro; Fujino, Takahiro; Yamamoto, Tokuo T; Nakajima, Kazunori
2018-01-01
Neuronal migration contributes to the establishment of mammalian brain. The extracellular protein Reelin sends signals to various downstream molecules by binding to its receptors, the apolipoprotein E receptor 2 (ApoER2) and very low-density lipoprotein receptor and exerts essential roles in the neuronal migration and formation of the layered neocortex. However, the cellular and molecular functions of Reelin signaling in the cortical development are not yet fully understood. Here, to gain insight into the role of Reelin signaling during cortical development, we examined the migratory behavior of Apoer2-deficient neurons in the developing brain. Stage-specific labeling of newborn neurons revealed that the neurons ectopically invaded the marginal zone (MZ) and that neuronal migration of both early- and late-born neurons was disrupted in the intermediate zone (IZ) in the Apoer2 KO mice. Rescue experiments showed that ApoER2 functions both in cell-autonomous and noncell-autonomous manners, that Rap1, integrin, and Akt are involved in the termination of migration beneath the MZ, and that Akt also controls neuronal migration in the IZ downstream of ApoER2. These data indicate that ApoER2 controls multiple processes in neuronal migration, including the early stage of radial migration and termination of migration beneath the MZ in the developing neocortex. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.
An adaptive reentry guidance method considering the influence of blackout zone
NASA Astrophysics Data System (ADS)
Wu, Yu; Yao, Jianyao; Qu, Xiangju
2018-01-01
Reentry guidance has been researched as a popular topic because it is critical for a successful flight. In view that the existing guidance methods do not take into account the accumulated navigation error of Inertial Navigation System (INS) in the blackout zone, in this paper, an adaptive reentry guidance method is proposed to obtain the optimal reentry trajectory quickly with the target of minimum aerodynamic heating rate. The terminal error in position and attitude can be also reduced with the proposed method. In this method, the whole reentry guidance task is divided into two phases, i.e., the trajectory updating phase and the trajectory planning phase. In the first phase, the idea of model predictive control (MPC) is used, and the receding optimization procedure ensures the optimal trajectory in the next few seconds. In the trajectory planning phase, after the vehicle has flown out of the blackout zone, the optimal reentry trajectory is obtained by online planning to adapt to the navigation information. An effective swarm intelligence algorithm, i.e. pigeon inspired optimization (PIO) algorithm, is applied to obtain the optimal reentry trajectory in both of the two phases. Compared to the trajectory updating method, the proposed method can reduce the terminal error by about 30% considering both the position and attitude, especially, the terminal error of height has almost been eliminated. Besides, the PIO algorithm performs better than the particle swarm optimization (PSO) algorithm both in the trajectory updating phase and the trajectory planning phases.
Silverman, A J; Hou-Yu, A; Oldfield, B J
1983-09-01
Since many peptidergic cell groups receive a diverse and complex monoaminergic innervation, we have developed a double-label procedure to visualize a peptide and a catecholamine in the same ultrathin section. Radiolabeled norepinephrine (NE) is applied locally and its reuptake into NE terminals is demonstrated by ultrastructural radioautography. Controls in this and other studies demonstrate that the NE labels only NE (and possibly epinephrine) terminals and not dopaminergic or serotonergic terminals. In the same tissue, vasopressin is localized by immunocytochemistry on unembedded sections that are subsequently embedded in epoxy resins for thin sectioning. The procedure as described here shows that NE terminals in the periventricular zone of the paraventricular nucleus of the hypothalamus innervate both vasopressin-positive and vasopressin-negative structures. This technique is useful in determining the chemical connectivity of the hypothalamus.
Romero-Fernandez, W.; Borroto-Escuela, D.O.; Vargas-Barroso, V.; Narváez, M.; Di Palma, M.; Agnati, L.F.; Sahd, J. Larriva
2014-01-01
Dopamine D1 and D2 receptor immunohistochemistry and Golgi techniques were used to study the structure of the adult rat arcuate-median eminence complex, and determine the distribution of the dopamine D1 and D2 receptor immunoreactivities therein, particularly in relation to the tubero-infundibular dopamine neurons. Punctate dopamine D1 and D2 receptor immunoreactivities, likely located on nerve terminals, were enriched in the lateral palisade zone built up of nerve terminals, while the densities were low to modest in the medial palisade zone. A codistribution of dopamine D1 receptor or dopamine D2 receptor immunoreactive puncta with tyrosine hydroxylase immunoreactive nerve terminals was demonstrated in the external layer. Dopamine D1 receptor but not dopamine D2 receptor immnunoreactivites nerve cell bodies were found in the ventromedial part of the arcuate nucleus and in the lateral part of the internal layer of the median eminence forming a continuous cell mass presumably representing neuropeptide Y immunoreactive nerve cell bodies. The major arcuate dopamine/ tyrosine hydroxylase nerve cell group was found in the dorsomedial part. A large number of tyrosine hydroxylase immunoreactive nerve cell bodies in this region demonstrated punctate dopamine D1 receptor immunoreactivity but only a few presented dopamine D2 receptor immunoreactivity which were mainly found in a substantial number of tyrosine hydroxylase cell bodies of the ventral periventricular hypothalamic nucleus, also belonging to the tuberoinfundibular dopamine neurons. Structural evidence for projections of the arcuate nerve cells into the median eminence was also obtained. Distal axons formed horizontal axons in the internal layer issuing a variable number of collaterals classified into single or multiple strands located in the external layer increasing our understanding of the dopamine nerve terminal networks in this region. Dopamine D1 and D2 receptors may therefore directly and differentially modulate the activity and/or Dopamine synthesis of substantial numbers of tubero-infundibular dopamine neurons at the somatic and terminal level. The immunohistochemical work also gives support to the view that dopamine D1 receptors and/or dopamine D2 receptors in the lateral palisade zone by mediating dopamine volume transmission may contribute to the inhibition of luteinizing hormone releasing hormone release from nerve terminals in this region. PMID:25308843
Romero-Fernandez, W; Borroto-Escuela, D O; Vargas-Barroso, V; Narváez, M; Di Palma, M; Agnati, L F; Larriva Sahd, J; Fuxe, K
2014-07-18
Dopamine D1 and D2 receptor immunohistochemistry and Golgi techniques were used to study the structure of the adult rat arcuate-median eminence complex, and determine the distribution of the dopamine D1 and D2 receptor immunoreactivities therein, particularly in relation to the tubero-infundibular dopamine neurons. Punctate dopamine D1 and D2 receptor immunoreactivities, likely located on nerve terminals, were enriched in the lateral palisade zone built up of nerve terminals, while the densities were low to modest in the medial palisade zone. A codistribution of dopamine D1 receptor or dopamine D2 receptor immunoreactive puncta with tyrosine hydroxylase immunoreactive nerve terminals was demonstrated in the external layer. Dopamine D1 receptor but not dopamine D2 receptor immnunoreactivites nerve cell bodies were found in the ventromedial part of the arcuate nucleus and in the lateral part of the internal layer of the median eminence forming a continuous cell mass presumably representing neuropeptide Y immunoreactive nerve cell bodies. The major arcuate dopamine/ tyrosine hydroxylase nerve cell group was found in the dorsomedial part. A large number of tyrosine hydroxylase immunoreactive nerve cell bodies in this region demonstrated punctate dopamine D1 receptor immunoreactivity but only a few presented dopamine D2 receptor immunoreactivity which were mainly found in a substantial number of tyrosine hydroxylase cell bodies of the ventral periventricular hypothalamic nucleus, also belonging to the tubero-infundibular dopamine neurons. Structural evidence for projections of the arcuate nerve cells into the median eminence was also obtained. Distal axons formed horizontal axons in the internal layer issuing a variable number of collaterals classified into single or multiple strands located in the external layer increasing our understanding of the dopamine nerve terminal networks in this region. Dopamine D1 and D2 receptors may therefore directly and differentially modulate the activity and /or Dopamine synthesis of substantial numbers of tubero-infundibular dopamine neurons at the somatic and terminal level. The immunohistochemical work also gives support to the view that dopamine D1 receptors and/or dopamine D2 receptors in the lateral palisade zone by mediating dopamine volume transmission may contribute to the inhibition of luteinizing hormone releasing hormone release from nerve terminals in this region.
NASA Astrophysics Data System (ADS)
Chaput, Marie; Famin, Vincent; Michon, Laurent
2017-10-01
To understand the volcano-tectonic history of Piton des Neiges (the dormant volcano of La Réunion), we measured in the field the orientation of sheeted intrusions and deformation structures, and interpreted the two datasets separately with a paleostress inversion. Results show that the multiple proposed rift zones may be simplified into three trends: (1) a N30°E, 5 km wide linear rift zone running to the south of the edifice, active in the shield building (≥ 2.48-0.43 Ma) and terminal stages (190-22 ka); (2) a curved N110 to N160°E rift zone, widening from 5 km to 10 km toward the NW flank, essentially active during the early emerged shield building (≥ 1.3 Ma); and (3) two sill zones, ≤ 1 km thick in total, in the most internal parts of the volcano, active in the shield building and terminal stages. In parallel, deformation structures reveal that the tectonics of the edifice consisted in three end-member stress regimes sharing common stress axes: (1) NW-SE extension affecting in priority the south of the edifice near the N30°E rift zone; (2) NNE-SSW extension on the northern half of the volcano near the N110-160°E rift zone; (3) compression occurring near the sill zones, with a NE-SW or NW-SE maximum principal stress. These three stress regimes are spatially correlated and mechanically compatible with the injection trends. Combined together, our data show that the emerged Piton des Neiges underwent sector spreading delimited by perpendicular rift zones, as observed on Piton de la Fournaise (the active volcano of La Réunion). Analogue experiments attribute such sector spreading to brittle edifices built on a weaker substratum. We therefore conclude that La Réunion volcanoes are both brittle, as opposed to Hawaiian volcanoes or Mount Etna whose radial spreading is usually attributed to a ductile body within the edifices.
Environmental Assessment for Terminal Area Improvements, Charleston International Airport
2011-11-17
Resources and/or USFWS . 7. An erosion and sedimentation control plan that includes the use of construction controls to prevent degradation of water...CCAA property and surrounding lands were historically used for phosphate fertilizer mining. Prior to the development of this property as an airport...number of zoning classifications which control land use within the city limits. The Airport is in an area zoned as "Light Industrial District" a
Fusion competent synaptic vesicles persist upon active zone disruption and loss of vesicle docking
Wang, Shan Shan H.; Held, Richard G.; Wong, Man Yan; Liu, Changliang; Karakhanyan, Aziz; Kaeser, Pascal S.
2016-01-01
In a nerve terminal, synaptic vesicle docking and release are restricted to an active zone. The active zone is a protein scaffold that is attached to the presynaptic plasma membrane and opposed to postsynaptic receptors. Here, we generated conditional knockout mice removing the active zone proteins RIM and ELKS, which additionally led to loss of Munc13, Bassoon, Piccolo, and RIM-BP, indicating disassembly of the active zone. We observed a near complete lack of synaptic vesicle docking and a strong reduction in vesicular release probability and the speed of exocytosis, but total vesicle numbers, SNARE protein levels, and postsynaptic densities remained unaffected. Despite loss of the priming proteins Munc13 and RIM and of docked vesicles, a pool of releasable vesicles remained. Thus, the active zone is necessary for synaptic vesicle docking and to enhance release probability, but releasable vesicles can be localized distant from the presynaptic plasma membrane. PMID:27537483
Freight Terminals Operating Environment
DOT National Transportation Integrated Search
1981-06-01
The research analysis has been directed toward (1) developing a realistic, quantitative description of the structure of the economic zones that are centered upon medium-size urban areas, (2) determining the nature of traffic in manufactured goods whi...
Structural controls of the Tuscarora geothermal field, Elko County, Nevada
NASA Astrophysics Data System (ADS)
Dering, G.; Faulds, J. E.
2012-12-01
Tuscarora is an amagmatic geothermal system located ~90 km northwest of Elko, Nevada, in the northern part of the Basin and Range province ~15 km southeast of the Snake River Plain. Detailed geologic mapping, structural analysis, and well data have been integrated to identify the structural controls of the Tuscarora geothermal system. The structural framework of the geothermal field is defined by NNW- to NNE-striking normal faults that are approximately orthogonal to the present extension direction. Boiling springs, fumaroles, and siliceous sinter emanate from a single NNE-striking, west-dipping normal fault. Normal faults west of these hydrothermal features mostly dip steeply east, whereas normal faults east of the springs primarily dip west. Thus, the springs, fumaroles, and sinter straddle a zone of interaction between fault sets that dip toward each other, classified as a strike-parallel anticlinal accommodation zone. Faults within the geothermal area are mostly discontinuous along strike with offsets of tens to hundreds of meters, whereas the adjacent range-bounding fault systems of the Bull Run and Independence Mountains accommodate several kilometers of displacement. The geothermal field lies within a broad step over between the southward terminating west-dipping Bull Run fault zone and the northward terminating west-dipping Independence Mountains fault zone. Neither of these major fault zones is known to host high temperature geothermal systems. The accommodation zone lies within the broad step over and contains both east-dipping antithetic and west-dipping synthetic faults. Accommodation zones are relatively common structural components of extended terranes that transfer strain between oppositely dipping fault sets via a network of subsidiary normal faults. This study has identified the hinge zone of an anticlinal accommodation zone as the site most conducive to fluid up-flow. The recognition of this specific portion of an accommodation zone as a favorable structural setting for geothermal activity may be a useful exploration tool for development of drilling targets in extensional terranes, as well as for developing geologic models of known geothermal fields. This type of information may ultimately help to reduce the risks of targeting successful geothermal wells in such settings.
Afferent innervation of the utricular macula in pigeons
NASA Technical Reports Server (NTRS)
Si, Xiaohong; Zakir, Mridha Md; Dickman, J. David
2003-01-01
Biotinylated dextran amine (BDA) was used to retrogradely label afferents innervating the utricular macula in adult pigeons. The pigeon utriclar macula consists of a large rectangular-shaped neuroepithelium with a dorsally curved anterior edge and an extended medioposterior tail. The macula could be demarcated into several regions based on cytoarchitectural differences. The striola occupied 30% of the macula and contained a large density of type I hair cells with fewer type II hair cells. Medial and lateral extrastriola zones were located outside the striola and contained only type II hair cells. A six- to eight-cell-wide band of type II hair cells existed near the center of the striola. The reversal line marked by the morphological polarization of hair cells coursed throughout the epithelium, near the peripheral margin, and through the center of the type II band. Calyx afferents innervated type I hair cells with calyceal terminals that contained between 2 and 15 receptor cells. Calyx afferents were located only in the striola region, exclusive of the type II band, had small total fiber innervation areas and low innervation densities. Dimorph afferents innervated both type I and type II hair cells with calyceal and bouton terminals and were primarily located in the striola region. Dimorph afferents had smaller calyceal terminals with few type I hair cells, extended fiber branches with bouton terminals and larger innervation areas. Bouton afferents innervated only type II hair cells in the extrastriola and type II band regions. Bouton afferents innervating the type II band had smaller terminal fields with fewer bouton terminals and smaller innervation areas than fibers located in the extrastriolar zones. Bouton afferents had the most bouton terminals on the longest fibers, the largest innervation areas with the highest innervation densities of all afferents. Among all afferents, smaller terminal innervation fields were observed in the striola and large fields were located in the extrastriola. The cellular organization and innervation patterns of the utricular maculae in birds appear to represent an organ in adaptive evolution, different from that observed for amphibians or mammals.
Infantry Weapons Test Methodology Study. Volume 3. Light Machine Gun Test Methodology
1972-06-01
Trajjectnry and marionim ordiwate. to the target increases beyond 500 meters, the beaten zone will become shorter and wider. When fires are de - livered into...traversing amount of elevation change is de - handwheel. To insure adequate tar- termined by the slope of the terrain get coverage, a burst is fired after and...to the traversing handwheel. The 6-mii increments on the traversing amount of elevation change Is de - handwheel. To insure adequate tar- termined by
Single-axis gyroscopic motion with uncertain angular velocity about spin axis
NASA Technical Reports Server (NTRS)
Singh, S. N.
1977-01-01
A differential game approach is presented for studying the response of a gyro by treating the controlled angular velocity about the input axis as the evader, and the bounded but uncertain angular velocity about the spin axis as the pursuer. When the uncertain angular velocity about the spin axis desires to force the gyro to saturation a differential game problem with two terminal surfaces results, whereas when the evader desires to attain the equilibrium state the usual game with single terminal manifold arises. A barrier, delineating the capture zone (CZ) in which the gyro can attain saturation and the escape zone (EZ) in which the evader avoids saturation is obtained. The CZ is further delineated into two subregions such that the states in each subregion can be forced on a definite target manifold. The application of the game theoretic approach to Control Moment Gyro is briefly discussed.
Lo, R Y; Levine, R L
1981-04-06
We have used [3H]proline radioautography to trace regenerating optic fibers in the goldfish following: (1) the removal of the right tectal lobe and the right eye, and (2) the removal of both tectal lobes. Our results indicate that following the removal of the right tectal lobe and the right eye, both the denervated tectal efferent pathways, and the denervated visual pathways and terminal zones of the enucleated eye were penetrated by the regenerating optic fibers. In addition, following bilateral lobectomy, the denervated tectal efferent pathways were bilaterally penetrated by the regenerating fibers. Since, in both types of operations, these denervated pathways and terminal zones should undergo degeneration, our results support the suggestion that the presence of degenerating axonal debris and proliferating glia may play an important role in guiding regenerating optic fibers in the visual system of the goldfish.
The structure and effect of suture zones in the Larsen C Ice Shelf, Antarctica
NASA Astrophysics Data System (ADS)
McGrath, Daniel; Steffen, Konrad; Holland, Paul R.; Scambos, Ted; Rajaram, Harihar; Abdalati, Waleed; Rignot, Eric
2014-03-01
Ice shelf fractures frequently terminate where they encounter suture zones, regions of material heterogeneity that form between meteoric inflows in ice shelves. This heterogeneity can consist of marine ice, meteoric ice with modified rheological properties, or the presence of fractures. Here, we use radar observations on the Larsen C Ice Shelf, Antarctica, to investigate (i) the termination of a 25 km long rift in the Churchill Peninsula suture zone, which was found to contain 60 m of accreted marine ice, and (ii) the along-flow evolution of a suture zone originating at Cole Peninsula. We determine a steady state field of basal melting/freezing rates and apply it to a flowline model to delineate the along-flow evolution of layers within the ice shelf. The thickening surface wedge of locally accumulated meteoric ice, which likely has limited lateral variation in its mechanical properties, accounts for 60% of the total ice thickness near the calving front. Thus, we infer that the lower 40% of the ice column and the material heterogeneities present there are responsible for resisting fracture propagation and thereby delaying tabular calving events, as demonstrated in the >40 year time series leading up to the 2004/2005 calving event for Larsen C. This likely represents a highly sensitive aspect of ice shelf stability, as changes in the oceanic forcing may lead to the loss of this heterogeneity.
Zonal variations in K+ currents in vestibular crista calyx terminals
Meredith, Frances L.
2014-01-01
We developed a rodent crista slice to investigate regional variations in electrophysiological properties of vestibular afferent terminals. Thin transverse slices of the gerbil crista ampullaris were made and electrical properties of calyx terminals in central zones (CZ) and peripheral zones (PZ) compared with whole cell patch clamp. Spontaneous action potential firing was observed in 25% of current-clamp recordings and was either regular or irregular in both zones. Firing was abolished when extracellular choline replaced Na+ but persisted when hair cell mechanotransduction channels or calyx AMPA receptors were blocked. This suggests that ion channels intrinsic to the calyx can generate spontaneous firing. In response to depolarizing voltage steps, outward K+ currents were observed at potentials above −60 mV. K+ currents in PZ calyces showed significantly more inactivation than currents in CZ calyces. Underlying K+ channel populations contributing to these differences were investigated. The KCNQ channel blocker XE991 dihydrochloride blocked a slowly activating, sustained outward current in both PZ and CZ calyces, indicating the presence of KCNQ channels. Mean reduction was greatest in PZ calyces. XE991 also reduced action potential firing frequency in CZ and PZ calyces and broadened mean action potential width. The K+ channel blocker 4-aminopyridine (10–50 μM) blocked rapidly activating, moderately inactivating currents that were more prevalent in PZ calyces. α-Dendrotoxin, a selective blocker of KV1 channels, reduced outward currents in CZ calyces but not in PZ calyces. Regional variations in K+ conductances may contribute to different firing responses in calyx afferents. PMID:25343781
Zonal variations in K+ currents in vestibular crista calyx terminals.
Meredith, Frances L; Rennie, Katherine J
2015-01-01
We developed a rodent crista slice to investigate regional variations in electrophysiological properties of vestibular afferent terminals. Thin transverse slices of the gerbil crista ampullaris were made and electrical properties of calyx terminals in central zones (CZ) and peripheral zones (PZ) compared with whole cell patch clamp. Spontaneous action potential firing was observed in 25% of current-clamp recordings and was either regular or irregular in both zones. Firing was abolished when extracellular choline replaced Na(+) but persisted when hair cell mechanotransduction channels or calyx AMPA receptors were blocked. This suggests that ion channels intrinsic to the calyx can generate spontaneous firing. In response to depolarizing voltage steps, outward K(+) currents were observed at potentials above -60 mV. K(+) currents in PZ calyces showed significantly more inactivation than currents in CZ calyces. Underlying K(+) channel populations contributing to these differences were investigated. The KCNQ channel blocker XE991 dihydrochloride blocked a slowly activating, sustained outward current in both PZ and CZ calyces, indicating the presence of KCNQ channels. Mean reduction was greatest in PZ calyces. XE991 also reduced action potential firing frequency in CZ and PZ calyces and broadened mean action potential width. The K(+) channel blocker 4-aminopyridine (10-50 μM) blocked rapidly activating, moderately inactivating currents that were more prevalent in PZ calyces. α-Dendrotoxin, a selective blocker of KV1 channels, reduced outward currents in CZ calyces but not in PZ calyces. Regional variations in K(+) conductances may contribute to different firing responses in calyx afferents. Copyright © 2015 the American Physiological Society.
[Microbial diversity of sediments from the coasts of Dalian Changshan Islands].
Li, Jialin; Wang, Zhonghua; Qin, Song; Wang, Guangyi
2011-05-01
To understand the impacts of anthropogenic activities on structure and composition of bacterial communities and to evaluate how bacterial communities respond to environmental gradients at coastal sediments. The diversity of bacterial communities in sediments from tourist and mariculture zones at coastal area of Dalian Changshan Islands was assessed using terminal restriction fragment length polymorphism (t-RFLP) and denaturing gradient gel electrophoresis (DGGE) approaches. Meanwhile, 16S rRNA clone library was constructed to reveal the composition and structure of bacterial communities in the most seriously polluted site (D4). There were much higher values of richness, Shannon-wiener and evenness index at D4 site by the analysis of terminal restriction fragments (t-RFs). The clustering result on the t-RFs areas and DGGE patterns showed that the bacterial diversity of tourist zone were more similar, while the distinction was increased with pollution levels among the tourist and mariculture zones. The 16S rRNA clone of D4 revealed that the Proteobacteria were the dominant phylum, and gamma-proteobacteria was the main class within Proteobacteria. The study documented changes in bacterial community structure by human impacts of mariculture than geographical location.
Dallaglio, Paolo Domenico; Anguera, Ignasi; Martínez Ferrer, José B; Pérez, Luisa; Viñolas, Xavier; Porres, Jose Manuel; Fontenla, Adolfo; Alzueta, Javier; Martínez, Juan Gabriel; Rodríguez, Aníbal; Basterra, Nuria; Sabaté, Xavier
2017-12-11
Fast ventricular tachycardias in the ventricular fibrillation zone in patients with an implantable cardioverter-defibrillator are susceptible to antitachycardia pacing (ATP) termination. Some manufacturers allow programming 2 ATP bursts: before charging (BC) and during (DC) charging. The aim of this study was to describe the safety and effectiveness of ATP BC and DC for fast ventricular tachycardias in the ventricular fibrillation zone in patients with an implantable cardioverter-defibrillator in daily clinical practice. Data proceeded from the multicenter UMBRELLA trial, including implantable cardioverter-defibrillator patients followed up by the CareLink monitoring system. Fast ventricular tachycardias in the ventricular fibrillation zone until a cycle length of 200ms with ATP BC and/or ATP DC were included. We reviewed 542 episodes in 240 patients. Two ATP bursts (BC/DC) were programmed in 291 episodes (53.7%, 87 patients), while 251 episodes (46.3%, 153 patients) had 1 ATP burst only DC. The number of episodes terminated by 1 ATP DC was 139, representing 55.4% effectiveness (generalized estimating equation-adjusted 60.4%). There were 256 episodes terminated by 1 or 2 ATP (BC/DC), representing 88% effectiveness (generalized estimating equation-adjusted 79.3%); the OR for ATP effectiveness BC/DC vs DC was 2.5, 95%CI, 1.5-4.1; P <.001. Shocked episodes were 112 (45%) for ATP DC vs 35 (12%) for ATP BC/DC, representing an absolute reduction of 73%. The mean shocked episode duration was 16seconds for ATP DC vs 19seconds for ATP BC/DC (P=.07). The ATP DC in the ventricular fibrillation zone for fast ventricular tachycardia is moderately effective. Adding an ATP burst BC increases the overall effectiveness, reduces the need for shocks, and does not prolong episode duration. Copyright © 2017 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.
The French short term radiopropagation predictions in the decameter band
NASA Technical Reports Server (NTRS)
Lassudrie-Duchesne, P.; Bourdila, A. M.; Sizun, H.
1979-01-01
Weekly and daily predictions of the ionospheric characteristics relevant to radio propagation are considered. A description of the techniques involved is given as well as examples showing how the prediction messages are prepared. The short term predictions are confined to restricted geographical areas and are relevant to radio circuits whose terminators are both located inside the same zone. They can be used with a reasonable approximation for circuits less than 3000 km of length whose reflection point lies within a given zone.
14 CFR 1.2 - Abbreviations and symbols.
Code of Federal Regulations, 2010 CFR
2010-01-01
... with runway alignment indicator lights. TACAN means ultra-high frequency tactical air navigational aid... touchdown zone lights. TVOR means very high frequency terminal omnirange station. V Ameans design... safety speed. VFRmeans visual flight rules. VHFmeans very high frequency. VORmeans very high frequency...
Code of Federal Regulations, 2011 CFR
2011-01-01
... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT COASTAL ZONE MANAGEMENT PROGRAM REGULATIONS Amendments to and Termination of Approved Management Programs § 923... coastal state may amend or modify a management program which it has submitted and which has been approved...
15 CFR 923.83 - Mediation of amendments.
Code of Federal Regulations, 2011 CFR
2011-01-01
...) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT COASTAL ZONE MANAGEMENT PROGRAM REGULATIONS Amendments to and Termination of Approved Management... “serious disagreements” between a Federal agency and a coastal State during administration of an approved...
Code of Federal Regulations, 2010 CFR
2010-01-01
... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT COASTAL ZONE MANAGEMENT PROGRAM REGULATIONS Amendments to and Termination of Approved Management Programs § 923... coastal state may amend or modify a management program which it has submitted and which has been approved...
Shigdel, Rajesh; Osima, Marit; Lukic, Marko; Ahmed, Luai A; Joakimsen, Ragnar M; Eriksen, Erik F; Bjørnerem, Åshild
2016-04-01
Bone architecture as well as size and shape is important for bone strength and risk of fracture. Most bone loss is cortical and occurs by trabecularization of the inner part of the cortex. We therefore wanted to identify determinants of the bone architecture, especially the area and porosity of the transitional zone, an inner cortical region with a large surface/matrix volume available for intracortical remodeling. In 211 postmenopausal women aged 54 to 94 years with nonvertebral fractures and 232 controls from the Tromsø Study, Norway, we quantified femoral subtrochanteric architecture in CT images using StrAx1.0 software, and serum levels of bone turnover markers (BTM, procollagen type I N-terminal propeptide and C-terminal cross-linking telopeptide of type I collagen). Multivariable linear and logistic regression analyses were used to quantify associations of age, weight, height, and bone size with bone architecture and BTM, and odds ratio (OR) for fracture. Increasing age, height, and larger total cross-sectional area (TCSA) were associated with larger transitional zone CSA and transitional zone CSA/TCSA (standardized coefficients [STB] = 0.11 to 0.80, p ≤ 0.05). Increasing weight was associated with larger TCSA, but smaller transitional zone CSA/TCSA and thicker cortices (STB = 0.15 to 0.22, p < 0.01). Increasing height and TCSA were associated with higher porosity of the transitional zone (STB = 0.12 to 0.46, p < 0.05). Increasing BTM were associated with larger TCSA, larger transitional zone CSA/TCSA, and higher porosity of each of the cortical compartments (p < 0.01). Fracture cases exhibited larger transitional zone CSA and higher porosity than controls (p < 0.001). Per SD increasing CSA and porosity of the transitional zone, OR for fracture was 1.71 (95% CI, 1.37 to 2.14) and 1.51 (95% CI, 1.23 to 1.85), respectively. Cortical bone architecture is determined mainly by bone size as built during growth and is modified by lifestyle factors throughout life through bone turnover. Fracture cases exhibited larger transitional zone area and porosity, highlighting the importance of cortical bone architecture for fracture propensity. © 2015 American Society for Bone and Mineral Research.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-04
...'s existing Site 1 would be categorized as a magnet site; Whereas, notice inviting public comment was... ASF sunset provision for magnet sites that would terminate authority for Site 1 if not activated by...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-01
... 244's existing Site 1 would be categorized as a magnet site; Whereas, notice inviting public comment... sunset provision for magnet sites that would terminate authority for Sites 2-7, 10-12 and 14 if not...
76 FR 58243 - Reorganization of Foreign-Trade Zone 41 Under Alternative Site Framework Milwaukee, WI
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-20
... 2-4 would be categorized as magnet sites, existing Sites 1 and 5 would be categorized as usage...-year ASF sunset provision for magnet sites that would terminate authority for Sites 2 and 4 if not...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-22
... following sites: Site 1 (1,830 acres)--Rivergate Industrial Park, Port Terminal Nos. 5 and 6, and the... Way and NE Alderwood Road, Portland; Site 3 (254 acres)--Portland Ship Repair Yard, 5555 N. Channel...
Utility of de-escalatory confidence-building measures
DOE Office of Scientific and Technical Information (OSTI.GOV)
Nation, J.
1989-06-01
This paper evaluates the utility of specific confidence-building de-escalatory measures and pays special attention to the evaluation of measures which place restrictions on or establish procedures for strategic forces. Some measures appear more promising than others. Potentially useful confidence-building measures largely satisfy defined criteria and include the phased return of strategic nuclear forces to peacetime bases and operations, the termination of interference with communications and NTMs (National Technical Means) and the termination of civil defense preparations. Less-promising CBMs include the standing down of supplemental early warning systems, the establishment of SSBN keep-out zones, and decreases in bomber alert rates. Establishmentmore » of SSBN keep-out zones and reduction in bomber rates are difficult to verify, while the standing-down of early warning systems provides little benefit at potentially large costs. Particular confidence-building measures (CBMs) may be most useful in building superpower confidence at specific points in the crisis termination phase. For example, a decrease in strategic bomber alert rates may provide some decrease in perception of the likelihood of war, but its potential costs, particularly in increasing bomber vulnerability, may limit its utility and implementation to the final crisis stages when the risks of re-escalation and surprise attack are lower.« less
Synapsin- and Actin-Dependent Frequency Enhancement in Mouse Hippocampal Mossy Fiber Synapses
Owe, Simen G.; Jensen, Vidar; Evergren, Emma; Ruiz, Arnaud; Shupliakov, Oleg; Kullmann, Dimitri M.; Storm-Mathisen, Jon; Walaas, S. Ivar; Hvalby, Øivind
2009-01-01
The synapsin proteins have different roles in excitatory and inhibitory synaptic terminals. We demonstrate a differential role between types of excitatory terminals. Structural and functional aspects of the hippocampal mossy fiber (MF) synapses were studied in wild-type (WT) mice and in synapsin double-knockout mice (DKO). A severe reduction in the number of synaptic vesicles situated more than 100 nm away from the presynaptic membrane active zone was found in the synapsin DKO animals. The ultrastructural level gave concomitant reduction in F-actin immunoreactivity observed at the periactive endocytic zone of the MF terminals. Frequency facilitation was normal in synapsin DKO mice at low firing rates (∼0.1 Hz) but was impaired at firing rates within the physiological range (∼2 Hz). Synapses made by associational/commissural fibers showed comparatively small frequency facilitation at the same frequencies. Synapsin-dependent facilitation in MF synapses of WT mice was attenuated by blocking F-actin polymerization with cytochalasin B in hippocampal slices. Synapsin III, selectively seen in MF synapses, is enriched specifically in the area adjacent to the synaptic cleft. This may underlie the ability of synapsin III to promote synaptic depression, contributing to the reduced frequency facilitation observed in the absence of synapsins I and II. PMID:18550596
Hattori, Takanari; Okamura, Hideo; Asaoka, Satoshi; Fukushi, Keiichi
2017-08-18
Transient isotachophoresis (tITP) with a system-induced terminator (SIT) was developed for capillary zone electrophoresis (CZE) determination of aniline (An + ) and pyridine (Py + ) in sewage samples. After sample injection, a water vial was set at the sample-inlet side. Then voltage was applied to generate a system-induced terminator (H + ). Experiments and simulations revealed a concentration effect by tITP with an SIT: background electrolyte (BGE) - 100mM acetic acid (AcOH) and 50mM NaOH (pH 4.6); detection wavelength - 200nm for An + and 254nm for Py + ; vacuum injection period - 15s (190nL); SIT generation - 10kV applied for 80s with the sample inlet side anode; separation voltage - 20kV with the sample inlet side anode. The limits of detection (LODs, S/N=3) of An + and Py + respectively reached 10 and 42μg/L, with good repeatability (peak area RSDs≤6.9%) and calibration graph linearity (R 2 =0.9997). The proposed method was applied for determination of An + and Py + in sewage samples. Recoveries of An + (0.50mg/L) and Py + (2.0mg/L) in spiked sewage samples were 94-104%. Copyright © 2017 Elsevier B.V. All rights reserved.
Flores, José-Abel; Filippelli, Gabriel M.; Sierro, Francisco J.; Latimer, Jennifer
2012-01-01
Paleoproductivity is a critical component in past ocean biogeochemistry, but accurate reconstructions of productivity are often hindered by limited integration of proxies. Here, we integrate geochemical (phosphorus) and micropaleontological proxies at millennial timescales, revealing that the coccolithophore record in the Subantarctic zone of the South Atlantic Ocean is driven largely by variations in marine phosphorus availability. A quantitative micropaleontological and geochemical analysis carried out in sediments retrieved from Ocean Drilling Program Site 1089 (Subantarctic Zone) reveals that most of the export productivity in this region over the last 0.5 my was due to coccolithophores. Glacial periods were generally intervals of high productivity, with productivity reaching a peak at terminations. Particularly high productivity was observed at Termination V and Termination IV, events that are characterized by high abundance of coccolithophores and maxima in the phosphorus/titanium and strontium/titanium records. We link the increase in productivity both to regional oceanographic phenomena, i.e., the northward displacement of the upwelling cell of the Antarctic divergence when the ice-sheet expanded, and to the increase in the inventory of phosphorus in the ocean due to enhanced transfer of this nutrient from continental margins during glacial lowstands in sea level. The Mid-Brunhes interval stands out from the rest of the record, being dominated by the small and highly calcified species Gephyrocapsa caribbeanica that provides most of the carbonate in these sediments. This likely represents higher availability of phosphorus in the surface ocean, especially in mesotrophic and oligotrophic zones. Under these condition, some coccolithophore species developed an r-strategy (opportunistic species; growth rate maximized) resulting in the bloom of G. caribbeanica. These seasonal blooms of may have induced “white tides” similar to those observed today in Emiliania huxleyi. PMID:22783242
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-26
...We, the U.S. Fish and Wildlife Service (Service), propose to remove the regulations that govern the southern sea otter (Enhydra lutris nereis) translocation program, including the establishment of an experimental population of southern sea otters, and all associated management actions. We are also proposing to amend the Authority citation for 50 CFR part 17 by removing the reference to Public Law 99- 625, the statute that authorized the Secretary to promulgate regulations establishing the southern sea otter translocation program. Removal of the regulations will terminate the program. We are proposing this action because we believe that the southern sea otter translocation program has failed to fulfill its purpose, as outlined in the southern sea otter translocation plan, and that our recovery and management goals for the species cannot be met by continuing the program. Our conclusion is based, in part, on an evaluation of the program against specific failure criteria established at the program's inception. This proposed action would terminate the designation of the experimental population of southern sea otters, abolish the southern sea otter translocation and management zones, and eliminate the current requirement to remove southern sea otters from San Nicolas Island and the management zone. This proposed rule would also eliminate future actions, required under the current regulations, to capture and relocate southern sea otters for the purpose of establishing an experimental population, and to remove southern sea otters in perpetuity from an ``otter-free'' management zone. As a result, it would allow southern sea otters to expand their range naturally into southern California waters. We have prepared a revised draft supplemental environmental impact statement (SEIS) and an initial regulatory flexibility analysis (IRFA) to accompany this proposed rule.
Geological setting of the southern termination of Western Alps
NASA Astrophysics Data System (ADS)
d'Atri, Anna; Piana, Fabrizio; Barale, Luca; Bertok, Carlo; Martire, Luca
2016-09-01
A revision of the stratigraphic and tectonic setting of the southern termination of the Western Alps, at the junction of the Maritime Alps with the westernmost Ligurian Alps, is proposed. In response to the Alpine kinematic evolution, a number of tectonic units formed on the deformed palaeo-European continental margin and were arranged in a NW-SE striking anastomosed pattern along the north-eastern boundary of the Argentera Massif. Because these tectonic units often cut across the palaeogeographic subdivision of the Alpine literature and show only partial affinity with their distinctive stratigraphic features, new attributions are proposed. The Subbriançonnais domain is here intended as a "deformation zone", and its tectonic units have been attributed to Dauphinois and Provençal domains; furthermore, the Eocene Alpine Foreland Basin succession has been interpreted, based on the affinity of its lithologic characters and age, as a single feature resting above all the successions of the different Mesozoic domains. The Cretaceous tectono-sedimentary evolution of the studied domains was characterized by intense tectonic controls on sedimentation inducing lateral variations of stratigraphic features and major hydrothermal phenomena. Since the early Oligocene, transpressional tectonics induced a NE-SW shortening, together with significant left-lateral movements followed by (late Oligocene-middle Miocene) right-lateral movements along E-W to SE-NW striking shear zones. This induced the juxtaposition and/or stacking of Briançonnais, Dauphinois and Ligurian tectonic units characterized by different metamorphic histories, from anchizonal to lower greenschist facies. This evolution resulted in the arrangement of the tectonostratigraphic units in a wide "transfer zone" accommodating the Oligocene WNW-ward movement of portions of the palaeo-European margin placed at the south-western termination of Western Alps and the Miocene dextral shearing along SE striking faults that bound the Argentera Massif on its NE side.
DOT National Transportation Integrated Search
2015-08-01
Many older reinforced concrete deck girder (RCDG) bridges contain straight-bar terminations of flexural reinforcement in : flexural tension zones without special detailing. Common bridge design practice of the 1950s did not consider the additional : ...
77 FR 54890 - Reorganization of Foreign-Trade Zone 94 Under Alternative Site Framework; Laredo, TX
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2012-09-06
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2010-11-08
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2013-09-27
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2012-12-21
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In situ bioremediation of an underground diesel fuel spill: A case history
NASA Astrophysics Data System (ADS)
Frankenberger, W. T.; Emerson, K. D.; Turner, D. W.
1989-05-01
In the winter months of 1983, approximately 1000 gallons of diesel fuel had flowed along an asphalt parking lot of a commercial establishment towards a surface drain near an open creek. Investigations led to the discovery of an underground storage tank leaking diesel fuel. Exploratory borings showed that contamination was near the surface horizon and the capillary zone of the water table. Hydrocarbon quantities ranged up to 1500 mg/kg of soil. The plume continued to move in an eastward direction toward the surface water of the creek. A laboratory study indicated relatively high numbers of hydrocarbon-oxidizing organisms relative to glucose-utilizing microorganisms in the unsaturated vadose zone. Bioreclamation was initiated in April 1984 by injecting nutrients (nitrogen and phosphorus) and hydrogen peroxide and terminated in October 1984 upon no detection (<1 mg/kg) of hydrocarbons. A verification boring within the vicinity of the contaminated plume confirmed that residual contamination had attained background levels. The monitoring program was terminated in January 1987.
Siebert, Matthias; Böhme, Mathias A; Driller, Jan H; Babikir, Husam; Mampell, Malou M; Rey, Ulises; Ramesh, Niraja; Matkovic, Tanja; Holton, Nicole; Reddy-Alla, Suneel; Göttfert, Fabian; Kamin, Dirk; Quentin, Christine; Klinedinst, Susan; Andlauer, Till Fm; Hell, Stefan W; Collins, Catherine A; Wahl, Markus C; Loll, Bernhard; Sigrist, Stephan J
2015-08-14
Synaptic vesicles (SVs) fuse at active zones (AZs) covered by a protein scaffold, at Drosophila synapses comprised of ELKS family member Bruchpilot (BRP) and RIM-binding protein (RBP). We here demonstrate axonal co-transport of BRP and RBP using intravital live imaging, with both proteins co-accumulating in axonal aggregates of several transport mutants. RBP, via its C-terminal Src-homology 3 (SH3) domains, binds Aplip1/JIP1, a transport adaptor involved in kinesin-dependent SV transport. We show in atomic detail that RBP C-terminal SH3 domains bind a proline-rich (PxxP) motif of Aplip1/JIP1 with submicromolar affinity. Pointmutating this PxxP motif provoked formation of ectopic AZ-like structures at axonal membranes. Direct interactions between AZ proteins and transport adaptors seem to provide complex avidity and shield synaptic interaction surfaces of pre-assembled scaffold protein transport complexes, thus, favouring physiological synaptic AZ assembly over premature assembly at axonal membranes.
Malá, Zdena; Gebauer, Petr
2017-10-06
Capillary isotachophoresis (ITP) is an electrophoretic technique offering high sensitivity due to permanent stacking of the migrating analytes. Its combination with electrospray-ionization mass-spectrometric (ESI-MS) detection is limited by the narrow spectrum of ESI-compatible components but can be compensated by experienced system architecture. This work describes a methodology for sensitive analysis of hydroxyderivatives of s-triazine herbicides, based on implementation of the concepts of moving-boundary isotachophoresis and of H + as essential terminating component into cationic ITP with ESI-MS detection. Theoretical description of such kind of system is given and equations for zone-related boundary mobilities are derived, resulting in a much more general definition of the effective mobility of the terminating H + zone than used so far. Explicit equations allowing direct calculation for selected simple systems are derived. The presented theory allows prediction of stacking properties of particular systems and easy selection of suitable electrolyte setups. A simple ESI-compatible system composed of acetic acid and ammonium with H + and ammonium as a mixed terminator was selected for the analysis of 2-hydroxyatrazine and 2-hydroxyterbutylazine, degradation products of s-triazine herbicides. The proposed method was tested with direct injection without any sample pretreatment and provided excellent linearity and high sensitivity with limits of detection below 100ng/L (0.5nM). Example analyses of unspiked and spiked drinking and river water are shown. Copyright © 2017 Elsevier B.V. All rights reserved.
Xu, Zhongqi; Kawahito, Kouji; Ye, Xiaoxue; Timerbaev, Andrei R; Hirokawa, Takeshi
2011-05-01
A further improvement of electrokinetic supercharging (EKS) methodology has been proposed, with the objective to enhance the sensitivity of the conventional CZE-UV method down to a single-digit part per trillion (ppt) level. The advanced EKS procedure is based on a novel phenomenon displaying the formation of a zone with an increased concentration of the hydrogen ion, capable to perform the function of a terminator, behind the sample zone upon electrokinetic injection. In combination with a visualizing co-ion of BGE, protonated 4-methylbenzylamine, acting as the leading ion, such system-induced terminator a effected the transient ITP state to efficiently concentrate cationic analytes prior to CZE. Furthermore, to amass more analyte ions within the effective electric field at the injection stage, a standard sample vial was replaced with an elongated vial that allowed the sample volume to be increased from 500 to 900 μL. Alongside, this replacement made the upright distance between the electrode and the capillary tips prolonged to 40.0 mm to achieve high-efficiency electrokinetic injection. The computer simulation was used for profiling analyte concentration, pH, and field strength in order to delineate formation of the terminator during sample injection. The proposed preconcentration strategy afforded an enrichment factor of 80,000 and thereby the LODs of rare-earth metal ions at the ppt level, e.g. 0.04 nM (6.7 ng/L) for erbium(III). Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Visual Map Development: Bidirectional Signaling, Bifunctional Guidance Molecules, and Competition
Feldheim, David A.; O’Leary, Dennis D. M.
2010-01-01
Topographic maps are a two-dimensional representation of one neural structure within another and serve as the main strategy to organize sensory information. The retina’s projection via axons of retinal ganglion cells to midbrain visual centers, the optic tectum/superior colliculus, is the leading model to elucidate mechanisms of topographic map formation. Each axis of the retina is mapped independently using different mechanisms and sets of axon guidance molecules expressed in gradients to achieve the goal of representing a point in the retina onto a point within the target. An axon’s termination along the temporal-nasal mapping axis is determined by opposing gradients of EphAs and ephrin-As that act through their forward and reverse signaling, respectively, within the projecting axons, each of which inhibits interstitial branching, cooperating with a branch-promoting activity, to generate topographic specific branching along the shaft of the parent axons that overshoot their correct termination zone along the anterior-posterior axis of the target. The dorsal-ventral termination position is then determined using a gradient of ephrin-B that can act as a repellent or attractant depending on the ephrin-B concentration relative to EphB levels on the interstitial branches to guide them along the medial-lateral axis of the target to their correct termination zone, where they arborize. In both cases, axon-axon competition results in axon mapping based on relative rather than absolute levels of repellent or attractant activity. The map is subsequently refined through large-scale pruning driven in large part by patterned retinal activity. PMID:20880989
In situ gasification process for producing product gas enriched in carbon monoxide and hydrogen
Capp, John P.; Bissett, Larry A.
1978-01-01
The present invention is directed to an in situ coal gasification process wherein the combustion zone within the underground coal bed is fed with air at increasing pressure to increase pressure and temperature in the combustion zone for forcing product gases and water naturally present in the coal bed into the coal bed surrounding the combustion zone. No outflow of combustion products occurs during the build-up of pressure and temperature in the combustion zone. After the coal bed reaches a temperature of about 2000.degree. F and a pressure in the range of about 100-200 psi above pore pressure the airflow is terminated and the outflow of the combustion products from the combustion zone is initiated. The CO.sub.2 containing gaseous products and the water bleed back into the combustion zone to react endothermically with the hot carbon of the combustion zone to produce a burnable gas with a relatively high hydrogen and carbon monoxide content. About 11 to 29 percent of the gas recovered from the combustion zone is carbon monoxide which is considerably better than the 4 to 10 percent carbon monoxide obtained by employing previously known coal gasification techniques.
Safety evaluation of joint and conventional lane merge configurations for freeway work zones.
Ishak, Sherif; Qi, Yan; Rayaprolu, Pradeep
2012-01-01
Inefficient operation of traffic in work zone areas not only leads to an increase in travel time delays, queue length, and fuel consumption but also increases the number of forced merges and roadway accidents. This study evaluated the safety performance of work zones with a conventional lane merge (CLM) configuration in Louisiana. Analysis of variance (ANOVA) was used to compare the crash rates for accidents involving fatalities, injuries, and property damage only (PDO) in each of the following 4 areas: (1) advance warning area, (2) transition area, (3) work area, and (4) termination area. The analysis showed that the advance warning area had higher fatality, injury, and PDO crash rates when compared to the transition area, work area, and termination area. This finding confirmed the need to make improvements in the advance warning area where merging maneuvers take place. Therefore, a new lane merge configuration, called joint lane merge (JLM), was proposed and its safety performance was examined and compared to the conventional lane merge configuration using a microscopic simulation model (VISSIM), which was calibrated with real-world data from an existing work zone on I-55 and used to simulate a total of 25 different scenarios with different levels of demand and traffic composition. Safety performance was evaluated using 2 surrogate measures: uncomfortable decelerations and speed variance. Statistical analysis was conducted to determine whether the differences in safety performance between both configurations were significant. The safety analysis indicated that JLM outperformed CLM in most cases with low to moderate flow rates and that the percentage of trucks did not have a significant impact on the safety performance of either configuration. Though the safety analysis did not clearly indicate which lane merge configuration is safer for the overall work zone area, it was able to identify the possibly associated safety changes within the work zone area under different traffic conditions. Copyright © 2012 Taylor & Francis Group, LLC
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2013-06-17
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2012-06-27
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2012-09-06
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2012-07-31
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Rheological separation of the megathrust seismogenic zone and episodic tremor and slip
NASA Astrophysics Data System (ADS)
Gao, Xiang; Wang, Kelin
2017-03-01
Episodic tremor and accompanying slow slip, together called ETS, is most often observed in subduction zones of young and warm subducting slabs. ETS should help us to understand the mechanics of subduction megathrusts, but its mechanism is still unclear. It is commonly assumed that ETS represents a transition from seismic to aseismic behaviour of the megathrust with increasing depth, but this assumption is in contradiction with an observed spatial separation between the seismogenic zone and the ETS zone. Here we propose a unifying model for the necessary geological condition of ETS that explains the relationship between the two zones. By developing numerical thermal models, we examine the governing role of thermo-petrologically controlled fault zone rheology (frictional versus viscous shear). High temperatures in the warm-slab environment cause the megathrust seismogenic zone to terminate before reaching the depth of the intersection of the continental Mohorovičić discontinuity (Moho) and the subduction interface, called the mantle wedge corner. High pore-fluid pressures around the mantle wedge corner give rise to an isolated friction zone responsible for ETS. Separating the two zones is a segment of semi-frictional or viscous behaviour. The new model reconciles a wide range of seemingly disparate observations and defines a conceptual framework for the study of slip behaviour and the seismogenesis of major faults.
Luo, Fujun; Dittrich, Markus; Stiles, Joel R.; Meriney, Stephen D.
2011-01-01
We used high-resolution fluorescence imaging and single-pixel optical fluctuation analysis to estimate the opening probability of individual voltage-gated calcium (Ca2+) channels during an action potential and the number of such Ca2+ channels within active zones of frog neuromuscular junctions. Analysis revealed ~36 Ca2+ channels within each active zone, similar to the number of docked synaptic vesicles but far less than the total number of transmembrane particles reported based on freeze-fracture analysis (~200–250). The probability that each channel opened during an action potential was only ~0.2. These results suggest why each active zone averages only one quantal release event during every other action potential, despite a substantial number of docked vesicles. With sparse Ca2+ channels and low opening probability, triggering of fusion for each vesicle is primarily controlled by Ca2+ influx through individual Ca2+ channels. In contrast, the entire synapse is highly reliable because it contains hundreds of active zones. PMID:21813687
Peripheral innervation patterns of vestibular nerve afferents in the bullfrog utriculus
NASA Technical Reports Server (NTRS)
Baird, Richard A.; Schuff, N. R.
1994-01-01
Vestibular nerve afferents innervating the bullfrog utriculus differ in their response dynamics and sensitivity to natural stimulation. They also supply hair cells that differ markedly in hair bundle morphology. To examine the peripheral innervation patterns of individual utricular afferents more closely, afferent fibers were labeled by the extracellular injection of horseradish peroxidase (HRP) into the vestibular nerve after sectioning the vestibular nerve medial to Scarpa's ganglion to allow the degeneration of sympathetic and efferent fibers. The peripheral arborizations of individual afferents were then correlated with the diameters of their parent axons, the regions of the macula they innervate, and the number and type of hair cells they supply. The utriculus is divided by the striola, a narrow zone of distinctive morphology, into media and lateral parts. Utiricular afferents were classified as striolar or extrastriolar according to the epithelial entrance of their parent axons and the location of their terminal fields. In general, striolar afferents had thicker parent axons, fewer subepithelial bifurcations, larger terminal fields, and more synaptic endings than afferents in extrstriolar regions. Afferents in a juxtastriolar zone, immediately adjacent to the medial striola, had innervation patterns transitional between those in the striola and more peripheral parts of the medial extrastriola. moast afferents innervated only a single macular zone. The terminal fields of striolar afferents, with the notable exception of a few afferents with thin parent axons, were generally confined to one side of the striola. Hair cells in the bullfrog utriculus have perviously been classified into four types based on hair bundle morphology. Afferents in the extrastriolar and juxtastriolar zones largely or exclusively innervated Type B hair cells, the predominant hair cell type in the utricular macula. Striolar afferents supplied a mixture of four hair cell types, but largely contacted Type B and Type C hair cells, particularly on the outer rows of the medial striola. Afferents supplying more central striolar regions innervated fewer Type B and larger numbers of Type E and Type F hair cells. Striolar afferents with thin parent axons largely supplied Type E hair cells with bulbed kniocilia in the innermost striolar rows.
NASA Technical Reports Server (NTRS)
Brady, Roland H., III; Cregan, Alan; Clayton, Jeff; Troxel, Bennie W.; Verosub, Kenneth L.; Abrams, Michael
1989-01-01
Analysis of processed images and detailed field investigations have provided significant information concerning the late-Pliocene and Quaternary evolution of the intersection of the Garlock and Death Valley fault zones. The imagery was used to determine patterns of sedimentation and age relationships on alluvial fans and to determine the geometry, styles of deformation, and relative ages of movements on major and minor faults in the study area. The field investigation often confirmed the inferences drawn from the images and provided additional tectonic and geomorphologic data about the Quaternary deformation of the region. All the data gathered in the course of this project support the contention that the Garlock fault zone terminates in the Avawatz Mountains and that the Death Valley fault zone continues south of the intersection for at least 50 km, forming the eastern boundary of the Mojave province.
Apparatus and method for continuous production of materials
Chang, Chih-hung; Jin, Hyungdae
2014-08-12
Embodiments of a continuous-flow injection reactor and a method for continuous material synthesis are disclosed. The reactor includes a mixing zone unit and a residence time unit removably coupled to the mixing zone unit. The mixing zone unit includes at least one top inlet, a side inlet, and a bottom outlet. An injection tube, or plurality of injection tubes, is inserted through the top inlet and extends past the side inlet while terminating above the bottom outlet. A first reactant solution flows in through the side inlet, and a second reactant solution flows in through the injection tube(s). With reference to nanoparticle synthesis, the reactant solutions combine in a mixing zone and form nucleated nanoparticles. The nucleated nanoparticles flow through the residence time unit. The residence time unit may be a single conduit, or it may include an outer housing and a plurality of inner tubes within the outer housing.
49 CFR 222.51 - Under what conditions will quiet zone status be terminated?
Code of Federal Regulations, 2010 CFR
2010-10-01
... agency responsible for grade crossing safety, and the State agency responsible for highway and road... agency responsible for grade crossing safety, the State agency responsible for highway and road safety... State agency responsible for grade crossing safety, the State agency responsible for highway and road...
49 CFR 222.51 - Under what conditions will quiet zone status be terminated?
Code of Federal Regulations, 2011 CFR
2011-10-01
... agency responsible for grade crossing safety, and the State agency responsible for highway and road... agency responsible for grade crossing safety, the State agency responsible for highway and road safety... State agency responsible for grade crossing safety, the State agency responsible for highway and road...
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2012-08-30
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2013-04-04
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2013-01-08
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2013-05-13
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NASA Astrophysics Data System (ADS)
Fernandes, A. M.; Smith, V.
2017-12-01
A downstream reduction in bed material flux is associated with the backwater zone, where rivers in their terminal reaches deepen to respond to the sea-level in the receiving basin. This downstream change in sediment transport is reflected in: a) lateral channel mobility, and b) sedimentology and stratigraphic architecture of composite depositional bodies that are left behind. Here we draw comparisons between the Mississippi River and the Trinity River (TX), in terms of bar morphologies and composition, and lateral mobility of these rivers. Across the backwater transition, both rivers display a slight increase in lateral migration rates, followed by substantial decrease lateral migration in the terminal reaches. Both rivers also display predominantly symmetrical channel cross-sections, coincident with very small migration rates in the terminal reaches. We will discuss how the divergence in sediment transport flux across the backwater zone relates to the volume and shape of bank-attached bars, which in turn relates to the cross-sectional shapes of the channels as well as their lateral migrations rates, and ultimately defines the internal architecture of the composite channel deposits that result. Furthermore, we draw comparisons between the morphologies of bank-attached bars and channels in rivers and submarine channels to present insights into how the dominant mode of sediment transport in these different environments ultimately controls the morphologies and kinematics of these channels.
Distinct compartmentalization of dentin matrix protein 1 fragments in mineralized tissues and cells.
Maciejewska, Izabela; Qin, Disheng; Huang, Bingzhen; Sun, Yao; Mues, Gabrielle; Svoboda, Kathy; Bonewald, Lynda; Butler, William T; Feng, Jerry Q; Qin, Chunlin
2009-01-01
Dentin matrix protein 1 (DMP1) has been shown to be critical for the formation of dentin and bone. However, the precise pathway by which DMP1 participates in dentinogenesis and osteogenesis remains to be clarified. DMP1 is present in the extracellular matrix of dentin and bone as processed NH(2)- and COOH-terminal fragments. The NH(2)-terminal fragment occurs as a proteoglycan, whereas the COOH-terminal fragment is highly phosphorylated. The differences in biochemical properties suggest that these fragments may have different tissue and cell distribution in association with distinct functions. In this study, we analyzed the distribution of the NH(2)- and COOH-terminal fragments of DMP1 in tooth, bone, osteocytes as well as MC3T3-E1 and HEK-293 cells. Immunohistochemical analyses were performed using antibodies specific to the NH(2)- or COOH-terminal region of DMP1. Clear differences in the distribution of these fragments were observed. In the teeth and bone, the NH(2)-terminal fragment was primarily located in the nonmineralized predentin and cartilage of the growth plate, while the COOH-terminal fragment accumulated in the mineralized zones. In osteocytes, the NH(2)-terminal fragment appeared more abundant along cell membrane and processes of osteocytes, while the COOH-terminal fragment was often found in the nuclei. This pattern of distribution in cellular compartments was further confirmed by analyses on MC3T3-E1 and HEK-293 cells transfected with a construct containing DMP1 cDNA. In these cell lines, the COOH-terminal fragment accumulated in cell nuclei, while the NH(2)-terminal fragment was in the cytosol. The different distribution of DMP1 fragments indicates that these DMP1 variants must perform distinct functions. Copyright 2008 S. Karger AG, Basel.
Liprin-α3 controls vesicle docking and exocytosis at the active zone of hippocampal synapses.
Wong, Man Yan; Liu, Changliang; Wang, Shan Shan H; Roquas, Aram C F; Fowler, Stephen C; Kaeser, Pascal S
2018-02-27
The presynaptic active zone provides sites for vesicle docking and release at central nervous synapses and is essential for speed and accuracy of synaptic transmission. Liprin-α binds to several active zone proteins, and loss-of-function studies in invertebrates established important roles for Liprin-α in neurodevelopment and active zone assembly. However, Liprin-α localization and functions in vertebrates have remained unclear. We used stimulated emission depletion superresolution microscopy to systematically determine the localization of Liprin-α2 and Liprin-α3, the two predominant Liprin-α proteins in the vertebrate brain, relative to other active-zone proteins. Both proteins were widely distributed in hippocampal nerve terminals, and Liprin-α3, but not Liprin-α2, had a prominent component that colocalized with the active-zone proteins Bassoon, RIM, Munc13, RIM-BP, and ELKS. To assess Liprin-α3 functions, we generated Liprin-α3-KO mice by using CRISPR/Cas9 gene editing. We found reduced synaptic vesicle tethering and docking in hippocampal neurons of Liprin-α3-KO mice, and synaptic vesicle exocytosis was impaired. Liprin-α3 KO also led to mild alterations in active zone structure, accompanied by translocation of Liprin-α2 to active zones. These findings establish important roles for Liprin-α3 in active-zone assembly and function, and suggest that interplay between various Liprin-α proteins controls their active-zone localization.
Song, Kyoung D; Rhim, Hyunchul; Kang, Tae Wook; Cha, Dong Ik; Yang, Jehoon
2017-01-01
Objective: To examine the gross pathology and histopathology of ablation zones created from radiofrequency (RF) ablation and to correlate their chronological changes. Methods: A total of 48 in vivo ablation zones (16 rabbit livers) were obtained immediately after and also 30 min, 1 h and 2 h after RF ablation and were subjected to haematoxylin and eosin (H&E) staining, nicotinamide adenine dinucleotide (NADH) diaphorase staining, terminal deoxynucleotidyl transferase dUTP nick end labelling (TUNEL) staining. Chronological changes in gross pathology and histopathology were evaluated and correlated with each other. Results: Peripheral red zones on gross pathology correlated with peripheral zones on H&E staining, lightly stained peripheral zones on NADH staining and peripheral positive zones on TUNEL staining. Central white zones on gross pathology correlated with combined central and border zones on H&E staining, central negative zones on NADH staining and combined central-positive and middle-negative zones on TUNEL staining. Boundary visibility between central white and peripheral red zones on gross pathology was significantly higher at 1 and 2 h than immediately after RF ablation. As time increased after RF ablation, visibility of the border zone on H&E staining and the grade of positively stained hepatocytes in the peripheral zone on TUNEL staining increased. Conclusion: Chronological changes in gross pathology of RF ablation zones correlated well with histopathology. The boundary between the central white and peripheral red zones tended to become clear at 1 h after RF ablation. Advances in knowledge: (1) RF ablation zones show chronological changes on gross pathology and histopathology. (2) Gross pathology and histopathology correlate well with each other. PMID:28139942
Rogiers, Suzy Y.; Clarke, Simon J.
2013-01-01
Heterogeneity in root-zone temperature both vertically and horizontally may contribute to the uneven vegetative and reproductive growth often observed across vineyards. An experiment was designed to assess whether the warmed half of a grapevine root zone could compensate for the cooled half in terms of vegetative growth and reproductive development. We divided the root system of potted Shiraz grapevines bilaterally and applied either a cool or a warm treatment to each half from budburst to fruit set. Shoot growth and inflorescence development were monitored over the season. Simultaneous cooling and warming of parts of the root system decreased shoot elongation, leaf emergence and leaf expansion below that of plants with a fully warmed root zone, but not to the same extent as those with a fully cooled root zone. Inflorescence rachis length, flower number and berry number after fertilization were smaller only in those vines exposed to fully cooled root zones. After terminating the treatments, berry enlargement and the onset of veraison were slowed in those vines that had been exposed to complete or partial root-zone cooling. Grapevines exposed to partial root-zone cooling were thus delayed in vegetative and reproductive development, but the inhibition was greater in those plants whose entire root system had been cooled. PMID:24244839
Shipboard fisheries management terminals
NASA Technical Reports Server (NTRS)
Nagler, R. G.; Sager, E. V.
1980-01-01
The needs of the National Marine Fisheries Service (NMGS), National Weather Service, and the U.S. Coast Guard for locational, biological, and environmental data were assessed. The fisheries conservation zones and the yellowfin tuna jurisdiction of the NMFS operates observer programs on foreign and domestic fishing vessels. Data input terminal and data transfer and processing technology are reviewed to establish available capability. A matrix of implementation options is generated to identify the benefits of each option, and preliminary cost estimates are made. Recommendations are made for incremental application of available off the shelf hardware to obtain improved performance and benefits within a well bounded cost. Terminal recommendations are made for three interdependent shipboard units emphasizing: (1) the determination of location and fishing activity; (2) hand held data inputting and formatting in the fishing work areas; and (3) data manipulation, merging, and editing.
Distribution of serine/threonine kinase SAD-B in mouse peripheral nerve synapse.
Hagiwara, Akari; Harada, Kenu; Hida, Yamato; Kitajima, Isao; Ohtsuka, Toshihisa
2011-05-11
The serine/threonine kinase SAD regulates neural functions such as axon/dendrite polarization and neurotransmitter release. In the vertebrate central nervous system, SAD-B, a homolog of Caenorhabditis elegans SAD-1, is associated with synaptic vesicles and the active zone cytomatrix in nerve terminals. However, the distribution of SAD-B in the peripheral nervous system remains elusive. Here, we show that SAD-B is specifically localized to neuromuscular junctions. Although the active zone protein bassoon showed a punctated signal indicating its localization to motor end plates, SAD-B shows relatively diffuse localization indicating its association with both the active zone and synaptic vesicles. Therefore, SAD kinase may regulate neurotransmitter release from motor end plates in a similar manner to its regulation of neurotransmitter release in the central nervous system.
49 CFR Appendix F to Subchapter B... - Commercial Zones
Code of Federal Regulations, 2014 CFR
2014-10-01
... Cincinnati, Ohio 8 Kansas City, Mo.-Kansas City, Kans. 9 Boston, Mass. 10 Davenport, Iowa; Rock Island and... with the right-of-way of the Chicago, Rock Island and Pacific Railroad, thence in an easterly direction... commercially a part of the San Pedro, Wilmington, and Terminal Island Districts of Los Angeles and Long Beach...
49 CFR Appendix F to Subchapter B... - Commercial Zones
Code of Federal Regulations, 2013 CFR
2013-10-01
... Cincinnati, Ohio 8 Kansas City, Mo.-Kansas City, Kans. 9 Boston, Mass. 10 Davenport, Iowa; Rock Island and... with the right-of-way of the Chicago, Rock Island and Pacific Railroad, thence in an easterly direction... commercially a part of the San Pedro, Wilmington, and Terminal Island Districts of Los Angeles and Long Beach...
49 CFR Appendix F to Subchapter B... - Commercial Zones
Code of Federal Regulations, 2012 CFR
2012-10-01
... Cincinnati, Ohio 8 Kansas City, Mo.-Kansas City, Kans. 9 Boston, Mass. 10 Davenport, Iowa; Rock Island and... with the right-of-way of the Chicago, Rock Island and Pacific Railroad, thence in an easterly direction... commercially a part of the San Pedro, Wilmington, and Terminal Island Districts of Los Angeles and Long Beach...
77 FR 3111 - Safety Zone; Export Grain Terminal (EGT), Columbia River, Longview, WA
Federal Register 2010, 2011, 2012, 2013, 2014
2012-01-23
... Homeland Security (DHS). Although this rule will restrict access to the regulated area, the effect of this... effects on them and participate in the rulemaking process. Small businesses may send comments on the... DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 165 [Docket No. USCG-2011-0532] RIN 1625...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-28
... entry, and FTZ 230's Sites 1-7, 9-11, 16- 18 and 20-22 would be categorized as magnet sites, and FTZ 230... sunset provision for magnet sites that would terminate authority for Sites 1, 3-7, 9-11, 16-18 and 20-22...
Lou, Xuelin
2018-01-01
The intact synaptic structure is critical for information processing in neural circuits. During synaptic transmission, rapid vesicle exocytosis increases the size of never terminals and endocytosis counteracts the increase. Accumulating evidence suggests that SV exocytosis and endocytosis are tightly connected in time and space during SV recycling, and this process is essential for synaptic function and structural stability. Research in the past has illustrated the molecular details of synaptic vesicle (SV) exocytosis and endocytosis; however, the mechanisms that timely connect these two fundamental events are poorly understood at central synapses. Here we discuss recent progress in SV recycling and summarize several emerging mechanisms by which synapses can “sense” the occurrence of exocytosis and timely initiate compensatory endocytosis. They include Ca2+ sensing, SV proteins sensing, and local membrane stress sensing. In addition, the spatial organization of endocytic zones adjacent to active zones provides a structural basis for efficient coupling between SV exocytosis and endocytosis. Through linking different endocytosis pathways with SV fusion, these mechanisms ensure necessary plasticity and robustness of nerve terminals to meet diverse physiological needs. PMID:29593500
NASA Astrophysics Data System (ADS)
Tong, C.; She, C. X.; Jin, Y. F.; Yang, P.; Huang, J. F.
2013-11-01
Methane production is influenced by the abundance of methanogens and the availability of terminal substrates. Sulfate-reducing bacteria (SRB) also play an important role in the anaerobic decomposition of organic matter. However, the relationships between methane production and methanogen populations, pore water terminal substrates in estuarine brackish marshes are poorly characterized, and even to our knowledge, no published research has explored the relationship between methane production rate and abundance of SRB and pore water dimethyl sulfide (DMS) concentration. We investigated methane production rate, abundances of methanogens and SRB, concentrations of pore water terminal substrates and electron acceptors at a brackish marsh landscape dominated by Phragmites australis, Cyperus malaccensis and Spatina alterniflora marshes zones in the Min River estuary. The average rates of methane production at a soil depth of 30 cm in the three marsh zones were 0.142, 0.058 and 0.067 μg g-1 d-1, respectively. The abundance of both methanogens and SRB in the soil of the P. australis marsh with highest soil organic carbon content was higher than in the C. malaccensis and S. alterniflora marshes. The abundance of methanogens and SRB in the three soil layers was statistically indistinguishable. Mean pore water DMS concentrations at a soil depth of 30 cm under the S. alterniflora marsh were higher than those in the C. malaccensis and P. australis marshes. Methane production rate increased with the abundance of both methanogens and SRB across three marsh zones together at the landscape scale, and also increased with the concentration of pore water acetate, but did not correlate with concentrations of pore water DMS and dissolved CO2. Our results suggest that, provided that substrates are available in ample supply, methanogens can continue to produce methane regardless of whether SRB are prevalent in estuarine brackish marshes.
NASA Astrophysics Data System (ADS)
Moffitt, S. E.; Moffitt, R.; Sauthoff, W.; Davis, C. V.; Hewett, K.; Hill, T. M.
2013-12-01
The expansion of low oxygen hydrographic zones in the modern ocean, known as Oxygen Minimum Zones (OMZ), has the potential to deteriorate ecosystems, alter ocean nutrient cycling and inflict mass mortality events upon benthic and pelagic communities. During the last deglaciation (18-10 ka), large, climate-driven changes in the oxygen content of the upper ocean occurred. We propose that previous climate-driven OMZ expansions are data-rich events with which to characterize the spatial scales of OMZ hydrographic perturbation, and the temporal scales of natural OMZ variability. Here we synthesize a global compilation of marine sediment records from modern OMZ regions to investigate deglacial changes in the vertical extent, intensity, and surface area impingements of hypoxic waters upon continental margins. We surveyed sediment core records within water depths of 183-3,296 meters below sea level (mbsl) and took advantage of cores with geochemical, sedimentary or microfossil oxygenation proxies to reconstruct the timing, depth and intensity of seafloor hypoxia. OMZ maximum vertical extent during the deglaciation was variable by region: Subarctic Pacific (~600-2,900 mbsl), California Current (~330-1,500 mbsl), Baja and Mexico (~330-830 mbsl), and Equatorial Pacific and Humboldt Current (~110-3,100 mbsl). Expansion timing is regionally coherent but not globally synchronous, such that Subarctic Pacific and California Current marginal areas exhibit tight correlation and oxygenation reversals with Northern Hemisphere deglacial events (Termination 1A, Bølling-Allerød, Younger Dryas and Termination 1B). Southern regions (Baja and Mexico, and the Equatorial Pacific and Humboldt Current) exhibit hypoxia expansion prior to Termination 1A (~16 ka), and no oxygenation reversals. Our analysis provides new evidence for the geospatially coherent and temporally rapid expansion of OMZs during the last deglaciation, and reveals the extreme shallowness of the upper hypoxic boundary in coastal waters during events of global-scale warming.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Barbaresi, P.; Fabri, M.; Conti, F.
Experiments were carried out on cats to ascertain whether corticocortical neurons of somatosensory areas I (SI) and II (SII) could be labelled by retrograde axonal transport of D-(/sup 3/H)aspartate (D-(/sup 3/H)Asp). This tritiated enantiomer of the amino acid aspartate is (1) taken up selectively by axon terminals of neurons releasing aspartate and/or glutamate as excitatory neurotransmitter, (2) retrogradely transported and accumulated in perikarya, (3) not metabolized, and (4) visualized by autoradiography. A solution of D-(/sup 3/H)Asp was injected in eight cats in the trunk and forelimb zones of SI (two cats) or in the forelimb zone of SII (six cats).more » In order to compare the labelling patterns obtained with D-(/sup 3/H)Asp with those resulting after injection of a nonselective neuronal tracer, horseradish peroxidase (HRP) was delivered mixed with the radioactive tracer in seven of the eight cats. Furthermore, six additional animals received HRP injections in SI (three cats; trunk and forelimb zones) or SII (three cats; forelimb zone). D-(/sup 3/H)Asp retrograde labelling of perikarya was absent from the ipsilateral thalamus of all cats injected with the radioactive tracer but a dense terminal plexus of anterogradely labelled corticothalamic fibers from SI and SII was observed, overlapping the distribution area of thalamocortical neurons retrogradely labelled with HRP from the same areas. D-(/sup 3/H)Asp-labelled neurones were present in ipsilateral SII (SII-SI association neurones) in cats injected in SI. In these animals a bundle of radioactive fibres was observed in the rostral portion of the corpus callosum entering the contralateral hemisphere. There, neurones retrogradely labelled with silver grains were present in SI (SI-SI callosal neurons).« less
Wu, F.T.; Liang, W.-T.; Lee, J.-C.; Benz, H.; Villasenor, A.
2009-01-01
The NW moving Philippine Sea plate (PSP) collides with the Eurasian plate (EUP) in the vicinity of Taiwan, and at the same time, it subducts toward the north along SW Ryukyu. The Ryukyu subduction zone terminates against eastern Taiwan. While the Ryukyu Trench is a linear bathym??trie low about 100 km east of Taiwan, closer to Taiwan, it cannot be clearly identified bathymetrically owing to the deformation related to the collision, making the location of the intersection of the Ryukyu with Taiwan difficult to decipher. We propose a model for this complex of boundaries on the basis of seismicity and 3-D velocity structures. In this model the intersection is placed at the latitude of about 23.7??N, placing the northern part of the Coastal Range on EUP. As PSP gets deeper along the subduction zone it collides with EUP on the Taiwan side only where they are in direct contact. Thus, the Eurasian plate on the Taiwan side is being pushed and compressed by the NW moving Philippine Sea plate, at increasing depth toward the north. Offshore of northeastern Taiwan the wedge-shaped EUP on top of the Ryukyu subducting plate is connected to the EUP on the Ryukyu side and coupled to the NW moving PSP by friction at the plate interface. The two sides of the EUP above the western end of the subduction zone are not subjected to the same forces, and a difference in motions can be expected. The deformation of Taiwan as revealed by continuous GPS measurements, geodetic movement along the east coast of Taiwan, and the formation of the Hoping Basin can be understood in terms of the proposed model. Copyright 2009 by the American Geophysical Union.
Interaction between cardiac myosin-binding protein C and formin Fhod3.
Matsuyama, Sho; Kage, Yohko; Fujimoto, Noriko; Ushijima, Tomoki; Tsuruda, Toshihiro; Kitamura, Kazuo; Shiose, Akira; Asada, Yujiro; Sumimoto, Hideki; Takeya, Ryu
2018-05-08
Mutations in cardiac myosin-binding protein C (cMyBP-C) are a major cause of familial hypertrophic cardiomyopathy. Although cMyBP-C has been considered to regulate the cardiac function via cross-bridge arrangement at the C-zone of the myosin-containing A-band, the mechanism by which cMyBP-C functions remains unclear. We identified formin Fhod3, an actin organizer essential for the formation and maintenance of cardiac sarcomeres, as a cMyBP-C-binding protein. The cardiac-specific N-terminal Ig-like domain of cMyBP-C directly interacts with the cardiac-specific N-terminal region of Fhod3. The interaction seems to direct the localization of Fhod3 to the C-zone, since a noncardiac Fhod3 variant lacking the cMyBP-C-binding region failed to localize to the C-zone. Conversely, the cardiac variant of Fhod3 failed to localize to the C-zone in the cMyBP-C-null mice, which display a phenotype of hypertrophic cardiomyopathy. The cardiomyopathic phenotype of cMyBP-C-null mice was further exacerbated by Fhod3 overexpression with a defect of sarcomere integrity, whereas that was partially ameliorated by a reduction in the Fhod3 protein levels, suggesting that Fhod3 has a deleterious effect on cardiac function under cMyBP-C-null conditions where Fhod3 is aberrantly mislocalized. Together, these findings suggest the possibility that Fhod3 contributes to the pathogenesis of cMyBP-C-related cardiomyopathy and that Fhod3 is critically involved in cMyBP-C-mediated regulation of cardiac function via direct interaction.
NASA Astrophysics Data System (ADS)
Schneider, Susanne; Rosenberg, Claudio; Hammerschmidt, Konrad
2010-05-01
The Tauern Window (TW) is the only domain within the Eastern Alps where deep crustal, Tertiary metamorphic rocks were exhumed to surface. The window is bounded by large-scale faults, partly considered to be responsible for its exhumation (e.g., Selverstone 1988, Fügenschuh 1997), and it is also cross cut internally by large-scale shear zones, whose significance in terms of type and timing of deformation, exhumation, and large-scale kinematic links is the subject of our investigation. These shear zones (Ahorn, Olperer, Greiner, Ahrntal) are widespread throughout the western TW, from the mm- to the km-scale. They are sinistral and located in the steep limbs of upright antiforms, forming a mylonitic foliation, that strikes parallel to the axial planes of these upright folds. We present new structural and geochronological data, obtained by in-situ dating of microstructurally defined syn- and postkinematic grains, to constrain the duration and termination of folding and sinistral shearing. Previous dating suggested initiation of shearing contemporaneous to nappe stacking between 32-and 30Ma, ongoing until 15Ma (Glodny et al., 2008). However, the fabric of the dated grains was not related to deformation phases defined from structural overprinting relationships, and the classical separation technique did not allow to separate synkinematic from pre- and post- kinematic grains. The northern margin of the western TW is pervasively overprinted by the Ahorn Shear Zone (Rosenberg & Schneider 2008), which shows S-side up kinematic indicators in addition to the sinistral ones, and a pronounced southward increase in metamorphic grade from lower greenschist facies to amphibolite facies conditions, within 2km. Phengites of the mylonitic foliation dated with the Rb/Sr in-situ technique, yield formation ages of 14-24Ma . The southern margin of the western TW is overprinted by the sinistral Ahrntal Fault (Schneider et al. 2009), which cuts discordantly several nappes from the Zentralgneiss to the Upper Austroalpine units. Within the Upper Penninic nappes N-side up kinematic indicators occur, in addition to the sinistral ones. Newly formed biotites of Zentralgneiss rocks have been dated with the Rb/Sr technique (Kitzig et al. 2009), yielding 18-20Ma for their formation during sinistral deformation. Fine-grained phengites from the axial plane foliation of the upright folds were dated with the K/Ar method, yielding 14-17Ma. Ar/Ar in-situ LA analyses of sinistral mylonites (Ahorn, Olperer and Greiner) yield formation ages of syn-kinematic phengites between 24-12Ma. These grains are overgrown by post-kinematic phengites of 12-9Ma. Northeast of the western TW, sinistral shear is accommodated by the brittle sinistral SEMP Fault system, whose activity has been dated to 17Ma (Peresson & Decker 1997). Several sinistral shear zones (Ahorn, Greiner, Ahrntal) of the western TW may coalesce into the SEMP Fault (e.g., Linzer et al., 2002). In the west, the Ahorn Shear Zone terminates nearly 10km east of the Brenner Fault, into a NW-striking fold belt. The Ahrntal Fault continues into the Jaufen Fault, which merges with the brittle sinistral Giudicarie Fault. Motion along the Giudicarie Fault initiated in the Miocene (Stipp et al., 2004), or already in the Oligocene (Müller et al 2001). Based on these results, a temporal, kinematic and geometric continuity between sinistral shearing along the Giudicarie Fault, along the SEMP Fault, and throughout the western TW, can be assessed. The sinistral shear zones of the western TW are kinematically linked to upright folds, hence to crustal thickening. Upright folding and sinistral shearing were active since 24Ma and terminated at 12Ma. In summary, the sinistral displacements of the Giudicarie System appear to be partitioned into upright folds and sinistral, transpressive shear zones in the western Tauern Window, both of which contribute to its exhumation. The coalescence of the sinistral shear zones into the SEMP Fault System coincides with the eastern termination of the ENE-striking upright folds, possibly indicating transfer of shortening into a strike-slip displacement. Therefore, the western TW as a whole, represents a Miocene, sinistral transpressive belt, accommodating sinistral displacements associated with South-Alpine indentation by folding and sinistral shearing, and transferring these into sinistral movements associated with lateral escape along the SEMP System, until 12 Ma.
Terminal zone glacial sediment transfer at a temperate overdeepened glacier system
NASA Astrophysics Data System (ADS)
Swift, D. A.; Cook, S. J.; Graham, D. J.; Midgley, N. G.; Fallick, A. E.; Storrar, R.; Toubes Rodrigo, M.; Evans, D. J. A.
2018-01-01
Continuity of sediment transfer through glacial systems is essential to maintain subglacial bedrock erosion, yet transfer at temperate glaciers with overdeepened beds, where subglacial fluvial sediment transport should be greatly limited by adverse slopes, remains poorly understood. Complex multiple transfer processes in temperate overdeepened systems has been indicated by the presence of large frontal moraine systems, supraglacial debris of mixed transport origin, thick basal ice sequences, and englacial thrusts and eskers. At Svínafellsjökull, thrusts comprising decimetre-thick debris-rich bands of stratified facies ice of basal origin, with a coarser size distribution and higher clast content than that observed in basal ice layers, contribute substantially to the transfer of subglacial material in the terminal zone. Entrainment and transfer of material occurs by simple shear along the upper surface of bands and by strain-induced deformation of stratified and firnified glacier ice below. Thrust material includes rounded and well-rounded clasts that are also striated, indicating that fluvial bedload is deposited as subglacial channels approach the overdeepening and then entrained along thrusts. Substantial transfer also occurs within basal ice, with facies type and debris content dependent on the hydrological connectedness of the adverse slope. A process model of transfer at glaciers with terminal overdeepenings is proposed, in which the geometry of the overdeepening influences spatial patterns of ice deformation, hydrology, and basal ice formation. We conclude that the significance of thrusting in maintaining sediment transfer continuity has likely been overlooked by glacier sediment budgets and glacial landscape evolution studies.
NASA Astrophysics Data System (ADS)
Kiselev, D. N.; Rogov, M. A.
2018-01-01
The genera Titanites and Glaucolithites, which were previously known only from the Portlandian of Northwestern Europe are now established in Epivirgatites nikitini Zone of European Russia. The Volgian species of Titanites are represented by both the endemic taxa Titanites (Paratitanites) manipulocostatus subgen. et sp. nov. and T. (Pseudogalbanites) triceps subgen. et sp. nov. and Titanites (Titanites) ex gr. titan Buckman of the Portland type. A new species Glaucolithites gardarikensis is described. It is likely that these ammonites migrated to the Central Russian Sea from northwestern Europe via the Norway-Greenland seaway and further to the Mezen-Pechora system of straits, which is supported by occurrences of Titanites in the north of Central Russia and Glaucolithites in East Greenland and on Spitsbergen. The direct and indirect correlations show that the middle part of the Nikitini Zone (Lahuseni Subzone) should at least partly be correlated with the Portlandian Kerbeus Zone.
A comparison of epithalamic, hypothalamic and spinal neurosecretory terminals.
Vigh-Teichmann, I; Vigh, B
1979-01-01
Nerve endings of epithalamic, hypothalamic and spinal neurosecretory areas were studied by light and electron microscopy in various vertebrates (from fishes up to mammals) including the lancelet. Areas investigated were the pineal organ, the pulvinar corporis pinealis, the neurohypophysis, the median eminence, the urophysis, the terminal filum and the medullo-spinal neurosecretory zones. We found that in all these areas the neurosecretory endings have common structures, which we call synaptic hemidesmosomes or neurohormonal terminals. These are characterized by accumulation of vesicles, and dense projections in a terminal on the basal lamina of the surface of the nervous tissue. A critical review of the literature suggests that a considerble neuroendocrine activity is associated with synaptic hemidesmosomes as special neurohormonal effector structures of the nerve cells. The cell-to-cell synapses formed by neurosecretory cells are discussed in connection with the dual capacity of these cells to function as both endocrine and "ordinary# neuronal elements. The importance of the external cerebrospinal fluid (CSF) space for the transport of materials released in the so-called neurohemal areas, is stressed.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-07
... following sites: Site 1 (338 acres) - within the 550-acre Phoenix Sky Harbor Center and adjacent air cargo terminal at the Phoenix Sky Harbor International Airport, Phoenix; Site 2 (18 acres) CC&F South Valley... to the Phoenix Sky Harbor International Airport, Phoenix. The grantee's proposed service area under...
NASA Technical Reports Server (NTRS)
Roddy, D. J.
1979-01-01
The geologic and core drilling studies described in the present paper show that the Flynn Creek crater has such distinctive morphological features as a broad flat hummocky floor; large central peak; locally terraced crater walls; uplifted, as well as flat-lying rim segments; and a surrounding ejecta blanket. The major structural features include a shallow depth of total brecciation and excavation as compared with apparent crater diameter; a thin breccia lens underlain by a thin zone of disrupted strata; concentric ring fault zones in inner rim, beneath crater wall, and outer crater floor regions; a large central uplift underlain by a narrow dipping zone of deeply disrupted strata; faulted, folded, brecciated, and fractured rim strata; and uplifted rim strata, which dip away from the crater, and flat-lying rim strata, which terminate as inward dipping rocks.
Recent Intermediate Depth Earthquakes in El Salvador, Central Mexico, Cascadia and South-West Japan
NASA Astrophysics Data System (ADS)
Lemoine, A.; Gardi, A.; Gutscher, M.; Madariaga, R.
2001-12-01
We studied occurence and source parameters of several recent intermediate depth earthquakes. We concentrated on the Mw=7.7 salvadorian earthquake which took place on January 13, 2001. It was a good example of the high seismic risk associated to such kind of events which occur closer to the coast than the interplate thrust events. The Salvadorian earthquake was an intermediate depth downdip extensional event which occured inside the downgoing Cocos plate, next to the downdip flexure where the dip increases sharply before the slab sinks more steeply. This location corresponds closely to the position of the Mw=5.7 1996 and Mw=7.3 1982 downdip extensional events. Several recent intermediate depth earthquakes occured in subduction zones exhibiting a ``flat slab'' geometry with three distinct flexural bends where flexural stress may be enhanced. The Mw=6.7 Geiyo event showed a downdip extensional mechanism with N-S striking nodal planes. This trend was highly oblique to the trench (Nankai Trough), yet consistent with westward steepening at the SW lateral termination of the SW Japan flat slab. The Mw=6.8 Olympia earthquake in the Cascadia subduction zone occured at the downdip termination of the Juan de Fuca slab, where plate dip increases from about 5o to over 30o. The N-S orientation of the focal planes, parallel to the trench indicated downdip extension. The location at the downdip flexure corresponds closely to the estimated positions of the 1949 M7.1 Olympia and 1965 M6.5 Seattle-Tacoma events. Between 1994 and 1999, in Central Mexico, an unusually high intermediate depth seismicity occured where several authors proposed a flat geometry for the Cocos plate. Seven events of magnitude between Mw=5.9 and Mw=7.1 occured. Three of them were downdip compressional and four where down-dip extensional. We can explain these earthquakes by flexural stresses at down-dip and lateral terminations of the supposed flat segment. Even if intermediate depth earthquakes occurence could be favored by stress transfer between intermediate depth and interplate zone during the earthquake cycle, flexural stresses associated with bendings which are not only present at ``flat slab'' geometry but also at ``normal'' dipping subduction zone, seem to govern the location of intermediate depth seismicity and to explain their focal mechanisms in El Salvador, SW Japon, Cascadia and Central Mexico.
Frederiksen, N.O.
1998-01-01
Strata comprising most of the upper Paleocene in eastern North America are divided into two new pollen zones, the Carya and Platycarya platycaryoides Interval Zones. Pollen data have proven to be important for correlations between Alabama-western Georgia and eastern Mississippi and between the eastern Gulf Coast and Virginia. Migration of tropical plant taxa from the Caribbean to the Gulf Coast began at least 4 m.y. before the end of the Paleocene. The Terminal Paleocene Extinction Event, accompanied by a distinct pulse of plant immigration from Europe, began several hundred thousand years before the end of the Paleocene.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Vivian, J. P.; Porter, C.; Wilce, J. A.
2006-11-01
A preparation of replication terminator protein (RTP) of B. subtilis and a 37-base-pair TerI sequence (comprising two binding sites for RTP) has been purified and crystallized. The replication terminator protein (RTP) of Bacillus subtilis binds to specific DNA sequences that halt the progression of the replisome in a polar manner. These terminator complexes flank a defined region of the chromosome into which they allow replication forks to enter but not exit. Forcing the fusion of replication forks in a specific zone is thought to allow the coordination of post-replicative processes. The functional terminator complex comprises two homodimers each of 29more » kDa bound to overlapping binding sites. A preparation of RTP and a 37-base-pair TerI sequence (comprising two binding sites for RTP) has been purified and crystallized. A data set to 3.9 Å resolution with 97.0% completeness and an R{sub sym} of 12% was collected from a single flash-cooled crystal using synchrotron radiation. The diffraction data are consistent with space group P622, with unit-cell parameters a = b = 118.8, c = 142.6 Å.« less
Code of Federal Regulations, 2012 CFR
2012-07-01
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2014-07-01
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2010-07-01
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Seismicity and plate tectonics in south central Alaska
NASA Technical Reports Server (NTRS)
Van Wormer, J. D.; Davies, J.; Gedney, L.
1974-01-01
Hypocenter distribution shows that the Benioff zone associated with the Aleutian arc terminates in interior Alaska some 75 km north of the Denali fault. There appears to be a break in the subducting Pacific plate in the Yentna River-Prince William Sound area which separates two seismically independent blocks, similar to the segmented structure reported for the central Aleutian arc.
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Bartel, Esther Maria; Neubauer, Franz; Heberer, Bianca; Genser, Johann
2014-12-01
Based on structural and fabric analyses at variable scales we investigate the evaporitic gypsum-dominated Comeglians-Paularo shear zone in the Southern Alps (Friuli). It represents the lateral western termination of the brittle Fella-Sava Fault. Missing dehydration products of gypsum and the lack of annealing indicate temperatures below 100 °C during development of the shear zone. Despite of such low temperatures the shear zone clearly exhibits mylonitic flow, thus evidencing laterally coeval activity of brittle and viscous deformation. The dominant structures within the gypsum rocks of the Lower Bellerophon Formation are a steeply to gently S-dipping foliation, a subhorizontal stretching lineation and pure shear-dominated porphyroclast systems. A subordinate simple shear component with dextral displacement is indicated by scattered σ-clasts. Both meso- and microscale structures are characteristic of a subsimple shear type of deformation with components of both coaxial and non-coaxial strain. Shortening in a transpressive regime was accommodated by right-lateral displacement and internal pure shear deformation within the Comeglians-Paularo shear zone. The shear zone shows evidence for a combination of two stretching faults, where stretching occurred in the rheologically weaker gypsum member and brittle behavior in enveloping lithologies.
Gravity Chromatic Imaging of the Eta Car's Core
NASA Astrophysics Data System (ADS)
Sanchez-Bermudez, Joel
2018-04-01
Eta Car is one of the most massive, and intriguing, Luminous Blue Variables known. In its core resides a binary with a 5.54 years orbital period. Visible, infrared, and X-raobservations suggest that the primary star exhibits a very dense wind with a terminal velocity of about 420 km/s, while the secondary shows a much faster and less dense wind with a terminal velocity of 3000 km/s. The wind-wind collision zone at the core of Eta Car is thus a complex region that deserves a detailed study to understand the effect of the binary interaction in the evolution of the system. Here, we will present a unique imaging campaign with GRAVITY/VLTI of the Eta Car's core. The superb quality of our interferometric data, together with state-of-the-art image reconstruction techniques, allowed us to obtain, with milliarcsecond resolution, continuum and chromatic images cross the BrG and HeI lines in the Eta Car K-band spectrum (R 4000). These new data together with models of the primary wind of Eta Car has letting us to characterize the spatial distribution of the dust and gas in the inner 40 AU wind-wind collision zone of the target.
Sedimentation in the Kane fracture zone, western North Atlantic
DOE Office of Scientific and Technical Information (OSTI.GOV)
Jaroslow, G.E.
1991-03-01
The Kane fracture zone, a deep narrow trough in oceanic crust, has provided an ideal depocenter for reservation on the seismic stratigraphic record of the North Atlantic basin. The acoustic stratigraphy in single-channel and multichannel seismic reflection profiles crossing the Kane fracture zone in the western North Atlantic has been examined in order to scrutinize age processes within a fracture zone. Maps of total sediment thickness have provided insight into overall sediment distribution and the influence of topography on sedimentation. Eight reflectors have been traced and correlated with lithostratigraphy at Deep Sea Drilling Project (DSDP) sites. The Bermuda Rise, amore » prominent topographic feature, has had a profound effect on the distribution of sediments within the fracture zone. Since late Eocene, the rise has blocked transport by turbidity currents of terrigenous sediments to distal portions of the fracture valley. A 1,000-m-thick turbidite pond within the fracture zone east of the Bermuda Rise has been determined to have been derived from local sources. Within the ponded sequence a seismic discontinuity is estimated to be early Oligocene and postdates the emergence of the Bermuda Rise, adding an independent age constraint on the development of the rise. The pond terminates against a structural dam at 55{degree}20W, east of which the fracture zone is essentially sediment starved.« less
Paleoceanographic insights on recent oxygen minimum zone expansion: lessons for modern oceanography.
Moffitt, Sarah E; Moffitt, Russell A; Sauthoff, Wilson; Davis, Catherine V; Hewett, Kathryn; Hill, Tessa M
2015-01-01
Climate-driven Oxygen Minimum Zone (OMZ) expansions in the geologic record provide an opportunity to characterize the spatial and temporal scales of OMZ change. Here we investigate OMZ expansion through the global-scale warming event of the most recent deglaciation (18-11 ka), an event with clear relevance to understanding modern anthropogenic climate change. Deglacial marine sediment records were compiled to quantify the vertical extent, intensity, surface area and volume impingements of hypoxic waters upon continental margins. By integrating sediment records (183-2,309 meters below sea level; mbsl) containing one or more geochemical, sedimentary or microfossil oxygenation proxies integrated with analyses of eustatic sea level rise, we reconstruct the timing, depth and intensity of seafloor hypoxia. The maximum vertical OMZ extent during the deglaciation was variable by region: Subarctic Pacific (~600-2,900 mbsl), California Current (~330-1,500 mbsl), Mexico Margin (~330-830 mbsl), and the Humboldt Current and Equatorial Pacific (~110-3,100 mbsl). The timing of OMZ expansion is regionally coherent but not globally synchronous. Subarctic Pacific and California Current continental margins exhibit tight correlation to the oscillations of Northern Hemisphere deglacial events (Termination IA, Bølling-Allerød, Younger Dryas and Termination IB). Southern regions (Mexico Margin and the Equatorial Pacific and Humboldt Current) exhibit hypoxia expansion prior to Termination IA (~14.7 ka), and no regional oxygenation oscillations. Our analyses provide new evidence for the geographically and vertically extensive expansion of OMZs, and the extreme compression of upper-ocean oxygenated ecosystems during the geologically recent deglaciation.
Paleoceanographic Insights on Recent Oxygen Minimum Zone Expansion: Lessons for Modern Oceanography
Moffitt, Sarah E.; Moffitt, Russell A.; Sauthoff, Wilson; Davis, Catherine V.; Hewett, Kathryn; Hill, Tessa M.
2015-01-01
Climate-driven Oxygen Minimum Zone (OMZ) expansions in the geologic record provide an opportunity to characterize the spatial and temporal scales of OMZ change. Here we investigate OMZ expansion through the global-scale warming event of the most recent deglaciation (18-11 ka), an event with clear relevance to understanding modern anthropogenic climate change. Deglacial marine sediment records were compiled to quantify the vertical extent, intensity, surface area and volume impingements of hypoxic waters upon continental margins. By integrating sediment records (183-2,309 meters below sea level; mbsl) containing one or more geochemical, sedimentary or microfossil oxygenation proxies integrated with analyses of eustatic sea level rise, we reconstruct the timing, depth and intensity of seafloor hypoxia. The maximum vertical OMZ extent during the deglaciation was variable by region: Subarctic Pacific (~600-2,900 mbsl), California Current (~330-1,500 mbsl), Mexico Margin (~330-830 mbsl), and the Humboldt Current and Equatorial Pacific (~110-3,100 mbsl). The timing of OMZ expansion is regionally coherent but not globally synchronous. Subarctic Pacific and California Current continental margins exhibit tight correlation to the oscillations of Northern Hemisphere deglacial events (Termination IA, Bølling-Allerød, Younger Dryas and Termination IB). Southern regions (Mexico Margin and the Equatorial Pacific and Humboldt Current) exhibit hypoxia expansion prior to Termination IA (~14.7 ka), and no regional oxygenation oscillations. Our analyses provide new evidence for the geographically and vertically extensive expansion of OMZs, and the extreme compression of upper-ocean oxygenated ecosystems during the geologically recent deglaciation. PMID:25629508
Lee, Taehee; Kim, Uhnoh
2012-04-01
In the mammalian somatic system, peripheral inputs from cutaneous and deep receptors ascend via different subcortical channels and terminate in largely separate regions of the primary somatosensory cortex (SI). How these inputs are processed in SI and then projected back to the subcortical relay centers is critical for understanding how SI may regulate somatic information processing in the subcortex. Although it is now relatively well understood how SI cutaneous areas project to the subcortical structures, little is known about the descending projections from SI areas processing deep somatic input. We examined this issue by using the rodent somatic system as a model. In rat SI, deep somatic input is processed mainly in the dysgranular zone (DSZ) enclosed by the cutaneous barrel subfields. By using biotinylated dextran amine (BDA) as anterograde tracer, we characterized the topography of corticostriatal and corticofugal projections arising in the DSZ. The DSZ projections terminate mainly in the lateral subregions of the striatum that are also known as the target of certain SI cutaneous areas. This suggests that SI processing of deep and cutaneous information may be integrated, to a certain degree, in this striatal region. By contrast, at both thalamic and prethalamic levels as far as the spinal cord, descending projections from DSZ terminate in areas largely distinguishable from those that receive input from SI cutaneous areas. These subcortical targets of DSZ include not only the sensory but also motor-related structures, suggesting that SI processing of deep input may engage in regulating somatic and motor information flow between the cortex and periphery. Copyright © 2011 Wiley-Liss, Inc.
NASA Astrophysics Data System (ADS)
Morley, C. K.
2016-04-01
The distribution of unconformities and end of Cenozoic rifting events in the South China Seas (SCS) reflects both the modes of rift development, and the effects of driving mechanisms. Continental rifting began in the eastern basins during the Paleocene, and propagated westwards to the Vietnam basin margin in the Late Eocene. Continental breakup around 32-28 Ma caused a regional reduction or cessation in extensional activity, particularly affecting basins furthest from the spreading centre. Basins in the slope and deepwater area north of the spreading centre exhibit reduced fault activity until 21-20 Ma. Propagation of oceanic crust westwards between ∼25 and 23 Ma, and termination of seafloor spreading sometime between 20.5 and 16 Ma affected fault activity in the Qiongdongnan, and Nam Con Song basins. In the Phu Khanh Basin and South, in the Dangerous Grounds area, extension continued until about 16 Ma, ending at the Red Unconformity. The end of seafloor spreading around 20.5 Ma reflects loss of extensional driving force as thinned continental crust entered the NW Borneo subduction zone. Controversially, a key component of the driving force maybe attributed to slab-pull. A transitional period of about 5-7 my between the onset of subduction of continental crust, and final jamming of the subduction zone (Deep Regional Unconformity, DRU) is inferred. The last pulse of extension was focussed in the western SCS, and terminated around 10.5 Ma. Detailed understanding of proto South China Seas development remains uncertain and controversial.
Ultrastructural Examination of Diffuse and Specific Tectopulvinar Projections in the Tree Shrew
CHOMSUNG, RANIDA D.; PETRY, HEYWOOD M.; BICKFORD, MARTHA E.
2008-01-01
Two pathways from the superior colliculus (SC) to the tree shrew pulvinar nucleus have been described, one in which the axons terminate in dense (or specific) patches and one in which the axon arbors are more diffusely organized (Luppino et al. [1988] J. Comp. Neurol. 273:67– 86). As predicted by Lyon et al. ([2003] J. Comp. Neurol. 467:593– 606), we found that anterograde labeling of the diffuse tectopulvinar pathway terminated in the acetylcholinesterase (AChE)-rich dorsal pulvinar (Pd), whereas the specific pathway terminated in the AChE-poor central pulvinar (Pc). Injections of retrograde tracers in Pd labeled non-γ-aminobutyric acid (GABA)-ergic wide-field vertical cells located in the lower stratum griseum superficiale and stratum opticum of the medial SC, whereas injections in Pc labeled similar cells in more lateral regions. At the ultrastructural level, we found that tectopulvinar terminals in both Pd and Pc contact primarily non-GABAergic dendrites. When present, however, synaptic contacts on GABAergic profiles were observed more frequently in Pc (31% of all contacts) compared with Pd (16%). Terminals stained for the type 2 vesicular glutamate transporter, a potential marker of tectopulvinar terminals, also contacted more GABAergic profiles in Pc (19%) compared with Pd (4%). These results provide strong evidence for the division of the tree shrew pulvinar into two distinct tectorecipient zones. The potential functions of these pathways are discussed. J. Comp. Neurol. 510:24 – 46, 2008. PMID:18615501
NASA Astrophysics Data System (ADS)
Le Gall, B.; Rolet, J.; Gernigon, L.; Ebinger, C.; Gloaguen, R.
2003-04-01
The southern tip zone of the Kenya Rift on the eastern branch of the East African System is usually thought to occur in the so-called North Tanzanian Divergence. In this region, the narrow (50 km-wide) axial graben of southern Kenya splays southwards, via a major EW-trending volcanic lineament, into a 200 km-wide broad rifted zone with three separate arms of normal faulting and tilted fault blocks (Eyasi, Manyara and Pangani arms from W to E). Remote sensing analysis from Central Tanzania demonstrates that rift morphology exists over an area lying 400 km beyond the southern termination of the Kenya Rift. The most prominent rift structures are observed in the Kilombero region and consist of a 100 km-wide range of uplifted basement blocks fringed to the west by an E-facing half-graben inferred to reach depths of 6-8 km from aeromagnetic dataset. Physiographic features (fault scarps), and river drainage anomalies suggest that the present-day rift pattern in the Kilombero extensional province principally results from Recent/Neogene deformation. That assumption is also supported by the seismogenic character of a number of faults. The Kilombero half-graben is superimposed upon an earlier rift system, Karoo in age, which is totally overprinted and is only evidenced from its sedimentary infill. On the other hand, the nature and thickness of the inferred Neogene synrift section is still unknown. The Kilombero rifted zone is assumed to connect northwards into the central rift arm (Manyara) of the South Kenya Rift via a seismically active transverse fault zone that follows ductile fabrics within the Mozambican crystalline basement. The proposed rift model implies that incipient rifting propagates hroughout the cold and strong crust/lithosphere of Central Tanzania along Proterozoic (N140=B0E) basement weakness zones and earlier Karoo (NS)rift structures. A second belt of Recent-active linked fault/basins also extends further East from the Pangani rift arm to the offshore Zanzibar-Kerimbas graben system. The structural connection of the Kilombero rifted zone with the Lake Malawi rift further south is also envisaged and should imply the link of the eastern and western branchs of the East African Rift System south of the Tanzanian craton.
Rollback of an intraoceanic subduction system and termination against a continental margin
NASA Astrophysics Data System (ADS)
Campbell, S. M.; Simmons, N. A.; Moucha, R.
2017-12-01
The Southeast Indian Slab (SEIS) seismic anomaly has been suggested to represent a Tethyan intraoceanic subduction system which operated during the Jurassic until its termination at or near the margin of East Gondwana (Simmons et al., 2015). As plate reconstructions suggest the downgoing plate remained coupled to the continental margin, this long-lived system likely experienced a significant amount of slab rollback and trench migration (up to 6000 km). Using a 2D thermomechanical numerical code that includes the effects of phase transitions, we test this interpretation by modeling the long-term subduction, transition zone stagnation, and rollback of an intraoceanic subduction system in which the downgoing plate remains coupled to a continental margin. In addition, we also investigate the termination style of such a system, with a particular focus on the potential for some continental subduction beneath an overriding oceanic plate. This work performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344. LLNL-ABS-735738
NASA Technical Reports Server (NTRS)
Ames, William G.
1990-01-01
Two satellite position reporting has been introduced into the OmniTRACS mobile satellite communication system. This system significantly improves position reporting reliability and accuracy while simplifying the terminal's hardware. The positioning technique uses the original OmniTRACS TDMA timing signal formats in the forward and return link directions plus an auxiliary, low power forward link signal through a second satellite to derive distance values. The distances are then converted into the mobile terminal's latitude and longitude in real time. A minor augmentation of the spread spectrum profile of the return link allowed the resolution of periodic ambiguities. The system also locates the two satellites in real time with fixed platforms in known locations using identical mobile terminal hardware. Initial accuracies of 1/4 mile have been realized uniformly throughout the USA using a satellite separation of 22 degrees and there are no dead zones, skywaves, or cycle slips as found in terrestrial systems like LORAN-C.
NASA Astrophysics Data System (ADS)
Ames, William G.
Two satellite position reporting has been introduced into the OmniTRACS mobile satellite communication system. This system significantly improves position reporting reliability and accuracy while simplifying the terminal's hardware. The positioning technique uses the original OmniTRACS TDMA timing signal formats in the forward and return link directions plus an auxiliary, low power forward link signal through a second satellite to derive distance values. The distances are then converted into the mobile terminal's latitude and longitude in real time. A minor augmentation of the spread spectrum profile of the return link allowed the resolution of periodic ambiguities. The system also locates the two satellites in real time with fixed platforms in known locations using identical mobile terminal hardware. Initial accuracies of 1/4 mile have been realized uniformly throughout the USA using a satellite separation of 22 degrees and there are no dead zones, skywaves, or cycle slips as found in terrestrial systems like LORAN-C.
Momentum microscopy of ? single crystals with detailed surface characterisation
NASA Astrophysics Data System (ADS)
Ellguth, M.; Tusche, C.; Iga, F.; Suga, S.
2016-11-01
We report the in situ preparation of surfaces of the proposed topological Kondo insulator SmB? by controlled cycles of Ar ion sputtering and annealing. The procedure provides a reproducible way for the preparation of Sm- or B-rich surface terminations by low (?1080 ?C) or high (?1200 ?C) temperature annealing. The surface quality and termination were checked by low energy electron diffraction and Auger electron spectroscopy. Photoemission studies were carried out using momentum microscopy and two laboratory light sources providing polarised radiation with an energy of 6 eV (fourth harmonic of a pulsed Ti:Sapphire laser) and unpolarised radiation with an energy of 21.2 eV (He-I line of a gas discharge lamp). Full dispersions of electronic states in a wide two-dimensional momentum space were obtained by momentum microscopy from the in situ prepared Sm-terminated surface. The shape of the Fermi surface is discussed based on the sections through the bulk Brillouin zone sampled by the different photon energies.
Terminal spacecraft rendezvous and capture with LASSO model predictive control
NASA Astrophysics Data System (ADS)
Hartley, Edward N.; Gallieri, Marco; Maciejowski, Jan M.
2013-11-01
The recently investigated ℓasso model predictive control (MPC) is applied to the terminal phase of a spacecraft rendezvous and capture mission. The interaction between the cost function and the treatment of minimum impulse bit is also investigated. The propellant consumption with ℓasso MPC for the considered scenario is noticeably less than with a conventional quadratic cost and control actions are sparser in time. Propellant consumption and sparsity are competitive with those achieved using a zone-based ℓ1 cost function, whilst requiring fewer decision variables in the optimisation problem than the latter. The ℓasso MPC is demonstrated to meet tighter specifications on control precision and also avoids the risk of undesirable behaviours often associated with pure ℓ1 stage costs.
Silver, Paul G; Behn, Mark D
2008-01-04
Although it is commonly assumed that subduction has operated continuously on Earth without interruption, subduction zones are routinely terminated by ocean closure and supercontinent assembly. Under certain circumstances, this could lead to a dramatic loss of subduction, globally. Closure of a Pacific-type basin, for example, would eliminate most subduction, unless this loss were compensated for by comparable subduction initiation elsewhere. Given the evidence for Pacific-type closure in Earth's past, the absence of a direct mechanism for termination/initiation compensation, and recent data supporting a minimum in subduction flux in the Mesoproterozoic, we hypothesize that dramatic reductions or temporary cessations of subduction have occurred in Earth's history. Such deviations in the continuity of plate tectonics have important consequences for Earth's thermal and continental evolution.
Seismic images of a Grenvillian terrane boundary
Milkereit, B.; Forsyth, D. A.; Green, A.G.; Davidson, A.; Hanmer, S.; Hutchinson, Deborah R.; Hinze, W. J.; Mereu, R.F.
1992-01-01
A series of gently dipping reflection zones extending to mid-crustal depths is recorded by seismic data from Lakes Ontario and Erie. These prominent reflection zones define a broad complex of southeast-dipping ductile thrust faults in the interior of the Grenville orogen. One major reflection zone provides the first image of a proposed Grenvillian suture—the listric boundary zone between allochthonous terranes of the Central Gneiss and Central Metasedimentary belts. Curvilinear bands of reflections that may represent "ramp folds" and "ramp anticlines" that originally formed in a deep crustal-scale duplex abut several faults. Vertical stacking of some curvilinear features suggests coeval or later out-of-sequence faulting of imbricated and folded thrust sheets. Grenvillian structure reflections are overlain by a thin, wedge-shaped package of shallow-dipping reflections that probably originates from sediments deposited in a local half graben developed during a period of post-Grenville extension. This is the first seismic evidence for such extension in this region, which could have occurred during terminal collapse of the Grenville orogen, or could have marked the beginning of pre-Appalachian continental rifting.
Cunningham, D.; Owen, L.A.; Snee, L.W.; Li, Ji
2003-01-01
The Barkol Tagh and Karlik Tagh ranges of the easternmost Tien Shan are a natural laboratory for studying the fault architecture of an active termination zone of a major intracontinental mountain range. Barkol and Karlik Tagh and lesser ranges to the north are bounded by active thrust faults that locally deform Quaternary sediments. Major thrusts in Karlik Tagh connect along strike to the east with the left-lateral Gobi-Tien Shan Fault System in SW Mongolia. From a Mongolian perspective. Karlik Tagh represents a large restraining bend for this regional strike-slip fault system, and the entire system of thrusts and strike-slip faults in the Karlik Tagh region defines a horsetail splay fault geometry. Regionally, there appears to be a kinematic transition from thrust-dominated deformation in the central Tien Shan to left-lateral transpressional deformation in the easternmost Tien Shan. This transition correlates with a general eastward decrease in mountain belt width and average elevation and a change in the angular relationship between the NNE-directed maximum horizontal stress in the region and the pre-existing basement structural grain, which is northwesterly in the central Tien Shan (orthogonal to SHmax) but more east-west in the eastern Tien Shan (acute angular relationship with SHmax . Ar-Ar ages indicate that major range-bounding thrusts in Barkol and Karlik Tagh are latest Permian-Triassic ductile thrust zones that underwent brittle reactivation in the Late Cenozoic. It is estimated that the modern mountain ranges of the extreme easternmost Tien Shan could have been constructed by only 10-15 km of Late Cenozoic horizontal shortening.
Upadhyaya, Giridhar; Clancy, Tara M; Brown, Jess; Hayes, Kim F; Raskin, Lutgarde
2012-11-06
Terminal electron accepting process (TEAP) zones developed when a simulated groundwater containing dissolved oxygen (DO), nitrate, arsenate, and sulfate was treated in a fixed-bed bioreactor system consisting of two reactors (reactors A and B) in series. When the reactors were operated with an empty bed contact time (EBCT) of 20 min each, DO-, nitrate-, sulfate-, and arsenate-reducing TEAP zones were located within reactor A. As a consequence, sulfate reduction and subsequent arsenic removal through arsenic sulfide precipitation and/or arsenic adsorption on or coprecipitation with iron sulfides occurred in reactor A. This resulted in the removal of arsenic-laden solids during backwashing of reactor A. To minimize this by shifting the sulfate-reducing zone to reactor B, the EBCT of reactor A was sequentially lowered from 20 min to 15, 10, and 7 min. While 50 mg/L (0.81 mM) nitrate was completely removed at all EBCTs, more than 90% of 300 μg/L (4 μM) arsenic was removed with the total EBCT as low as 27 min. Sulfate- and arsenate-reducing bacteria were identified throughout the system through clone libraries and quantitative PCR targeting the 16S rRNA, dissimilatory (bi)sulfite reductase (dsrAB), and dissimilatory arsenate reductase (arrA) genes. Results of reverse transcriptase (RT) qPCR of partial dsrAB (i.e., dsrA) and arrA transcripts corresponded with system performance. The RT qPCR results indicated colocation of sulfate- and arsenate-reducing activities, in the presence of iron(II), suggesting their importance in arsenic removal.
Friedman, Elliot S.; McPhillips, Lauren E.; Werner, Jeffrey J.; Poole, Angela C.; Ley, Ruth E.; Walter, M. Todd; Angenent, Largus T.
2016-01-01
Dissimilatory metal-reducing bacteria are widespread in terrestrial ecosystems, especially in anaerobic soils and sediments. Thermodynamically, dissimilatory metal reduction is more favorable than sulfate reduction and methanogenesis but less favorable than denitrification and aerobic respiration. It is critical to understand the complex relationships, including the absence or presence of terminal electron acceptors, that govern microbial competition and coexistence in anaerobic soils and sediments, because subsurface microbial processes can effect greenhouse gas emissions from soils, possibly resulting in impacts at the global scale. Here, we elucidated the effect of an inexhaustible, ferrous-iron and humic-substance mimicking terminal electron acceptor by deploying potentiostatically poised electrodes in the sediment of a very specific stream riparian zone in Upstate New York state. At two sites within the same stream riparian zone during the course of 6 weeks in the spring of 2013, we measured CH4 and N2/N2O emissions from soil chambers containing either poised or unpoised electrodes, and we harvested biofilms from the electrodes to quantify microbial community dynamics. At the upstream site, which had a lower vegetation cover and highest soil temperatures, the poised electrodes inhibited CH4 emissions by ∼45% (when normalized to remove temporal effects). CH4 emissions were not significantly impacted at the downstream site. N2/N2O emissions were generally low at both sites and were not impacted by poised electrodes. We did not find a direct link between bioelectrochemical treatment and microbial community membership; however, we did find a correspondence between environment/function and microbial community dynamics. PMID:26793170
Urbánek, Marek; Pospísilová, Marie; Polásek, Miroslav
2002-04-01
The combination of capillary isotachophoresis (ITP) and capillary zone electrophoresis (CZE) in the column coupling configuration was optimized in a mode where the electrolyte for the CZE step is different from the leading and terminating ITP electrolytes. Two colored markers, picric acid and 1-nitroso-2-naphthol, were used for exact timing of the transfer of isotachophoretically stacked analyte zones into the CZE column and for the control of the residual amount of the leading and terminating ITP electrolytes entering the CZE capillary together with the analytes, thus controlling the duration of transient ITP migration in the CZE capillary and ensuring good separation of the analytes and reproducibility of the migration times (relative standard deviations 1%). ITP-CZE was applied to the simultaneous assay of several cinnamic acid derivatives and flavonoids in methanolic extracts of Sambucus flowers and Crataegus leaves and flowers. The preconcentrating and cleansing effect of the ITP step allowed injection of relatively large sample volumes (30 microL). The limits of detection were approximately 20-50 ng x mL(-1) and 100 ng x mL(-1) for the acids and flavonoids, respectively ( thick similar 200-times lower compared to conventional CE) with spectrophotometric detection at 254 nm. The ITP-CZE exhibited satisfactory linearity and precision when using CZE buffer of pseudo "pH" 9.0; 1-nitroso-2-naphthol was employed as the internal standard. The separation took approximately 35 min. The ITP-CZE results for rutin, hyperoside, and vitexin-2-O"-rhamnoside were in good accordance with those obtained previously by high-performance liquid chromatography.
Lessons Learned on Bioaugmentation of DNAPL Source Zone Areas
2007-10-01
but rather have stringers, ganglia or blobs that can create an “effective pool length”. As the leading edge of these discontinuous DNAPL free-phases...terminal restriction fragment length polymorphism (T-RFLP), denaturing gradient gel electrophoresis (DGGE), and fluorescent in situ hybridization ( FISH ...question of interest (e.g. PCR, FISH , DGGE); (ii) sampling location(s); (iii) an appropriate sampling procedure; and (iv) an appropriate sample handling
Propagation measurements in Alaska using ACTS beacons
NASA Technical Reports Server (NTRS)
Mayer, Charles E.
1991-01-01
The placement of an ACTS propagation terminal in Alaska has several distinct advantages. First is the inclusion of a new and important climatic zone to the global propagation model. Second is the low elevation look angle from Alaska to ACTS. These two unique opportunities also present problems unique to the location, such as extreme temperatures and lower power levels. These problems are examined and compensatory solutions are presented.
NASA Astrophysics Data System (ADS)
Lamarche, Geoffroy; Lebrun, Jean-Frédéric
2000-01-01
South of New Zealand the Pacific-Australia (PAC-AUS) plate boundary runs along the intracontinental Alpine Fault, the Puysegur subduction front and the intraoceanic Puysegur Fault. The Puysegur Fault is located along Puysegur Ridge, which terminates at ca. 47°S against the continental Puysegur Bank in a complex zone of deformation called the Snares Zone. At Puysegur Trench, the Australian Plate subducts beneath Puysegur Bank and the Fiordland Massif. East of Fiordland and Puysegur Bank, the Moonlight Fault System (MFS) represents the Eocene strike-slip plate boundary. Interpretation of seafloor morphology and seismic reflection profiles acquired over Puysegur Bank and the Snares Zone allows study of the transition from intraoceanic strike-slip faulting along the Puysegur Ridge to oblique subduction at the Puysegur Trench and to better understand the genetic link between the Puysegur Fault and the MFS. Seafloor morphology is interpreted from a bathymetric dataset compiled from swath bathymetry data acquired during the 1993 Geodynz survey, and single beam echo soundings acquired by the NZ Royal Navy. The Snares Zone is the key transition zone from strike-slip faulting to subduction. It divides into three sectors, namely East, NW and SW sectors. A conspicuous 3600 m-deep trough (the Snares Trough) separates the NW and East sectors. The East sector is characterised by the NE termination of Puysegur Ridge into right-stepping en echelon ridges that accommodate a change of strike from the Puysegur Fault to the MFS. Between 48°S and 47°S, in the NW sector and the Snares Trough, a series of transpressional faults splay northwards from the Puysegur Fault. Between 49°50'S and 48°S, thrusts develop progressively at Puysegur Trench into a decollement. North of 48°S the Snares Trough develops between two splays of the Puysegur Fault, indicating superficial extension associated with the subsidence of Puysegur Ridge. Seismic reflection profiles and bathymetric maps show a series of transpressional faults that splay northwards across the Snares Fault, and terminate at the top of the Puysegur trench slope. Between ca. 48°S and 46°30'S, the relative plate motion appears to be distributed over the Puysegur subduction zone and the strike-slip faults located on the edge of the upper plate. Conversely, north of ca. 46°S, a lack of active strike-slip faulting along the MFS and across most of Puysegur Bank indicates that the subduction in the northern part of Puysegur Trench accounts for most of the oblique convergence. Hence, active transpression in the Snares fault zone indicates that the relative PAC-AUS plate motion is transferred from strike-slip faulting along the Puysegur Fault to subduction at Puysegur Trench. The progressive transition from thrusts at Puysegur Trench and strike-slip faulting at the Puysegur Fault to oblique subduction at Puysegur Trench suggests that the subduction interface progressively developed from a western shallow splay of the Puysegur Fault. It implies that the transfer fault links the subduction interface at depth. A tectonic sliver is identified between Puysegur Trench and the Puysegur Fault. Its northwards motion relative to the Pacific Plate implies that is might collide with Puysegur Bank.
NASA Astrophysics Data System (ADS)
Kim, U.; Parker, J.; Borden, R. C.
2014-12-01
In-situ chemical oxidation (ISCO) has been applied at many dense non-aqueous phase liquid (DNAPL) contaminated sites. A stirred reactor-type model was developed that considers DNAPL dissolution using a field-scale mass transfer function, instantaneous reaction of oxidant with aqueous and adsorbed contaminant and with readily oxidizable natural oxygen demand ("fast NOD"), and second-order kinetic reactions with "slow NOD." DNAPL dissolution enhancement as a function of oxidant concentration and inhibition due to manganese dioxide precipitation during permanganate injection are included in the model. The DNAPL source area is divided into multiple treatment zones with different areas, depths, and contaminant masses based on site characterization data. The performance model is coupled with a cost module that involves a set of unit costs representing specific fixed and operating costs. Monitoring of groundwater and/or soil concentrations in each treatment zone is employed to assess ISCO performance and make real-time decisions on oxidant reinjection or ISCO termination. Key ISCO design variables include the oxidant concentration to be injected, time to begin performance monitoring, groundwater and/or soil contaminant concentrations to trigger reinjection or terminate ISCO, number of monitoring wells or geoprobe locations per treatment zone, number of samples per sampling event and location, and monitoring frequency. Design variables for each treatment zone may be optimized to minimize expected cost over a set of Monte Carlo simulations that consider uncertainty in site parameters. The model is incorporated in the Stochastic Cost Optimization Toolkit (SCOToolkit) program, which couples the ISCO model with a dissolved plume transport model and with modules for other remediation strategies. An example problem is presented that illustrates design tradeoffs required to deal with characterization and monitoring uncertainty. Monitoring soil concentration changes during ISCO was found to be important to avoid decision errors associated with slow rebound of groundwater concentrations.
NASA Astrophysics Data System (ADS)
Schneider, Susanne; Hammerschmidt, Konrad; Rosenberg, Claudio Luca
2010-05-01
The internal structure of the Tauern Window (TW) consists of parallel sets of upright antiforms, striking ENE in the west and ESE in the east. The long axes of the upright folds are parallel to shear zones (SZ), which are generally sinistral in the west and dextral in the east. The formation of these structures has been interpreted as the result of a coeval, conjugate system, forming in response to south-Alpine indentation (Rosenberg et al., 2004), or as a change in the regional shortening direction through time (Polinski and Eisbacher, 1992; Neubauer et al., 2000; Mancktelow et al., 2001). The latter models suggested an Oligocene age for sinistral displacements, followed by Miocene dextral ones. Therefore, determining the timing of these different shear zones is a key to understand the tectonic significance of the structures described above. We analysed the kinematics and determined the formation age of the mylonitic foliation of two sinistral shear zones in the western TW (Ahorn SZ, Olperer SZ). In addition to left lateral displacements, kinematic indicators in the YZ plane for both shear zones point to differential vertical displacements, namely S-side up. We performed absolute age determinations of deformation by dating syn- and on post-kinematically grown minerals, the latter overprinting the former ones microstructurally on the microscopic scale. For this purpose we selected syn-kinematic phengites of mylonites and ultra-mylonites from shear bands, strain caps and also from overprinting statically grown phengites overprinting the mylonitic foliation. The Ar/Ar In-situ UV-laser ablation method was applied using a noble gas mass spectrometer. For comparison micas of an undeformed host rock were also dated using the same method. The obtained age values of syn-kinematic phengites vary between 12-24 Ma. This age variation is commonly found within single grains. Postkinematic, phengites overgrowing the syn-kinematic grains yield the youngest age values, namely 5-12 Ma. We observe a systematic relationship between the ages of the postkinematic grains and the age spread of the syn-kinematic ones. The age of the post-kinematic grains always coincides with the youngest age determined within the syn-kinematic grains. We interpret this relationship as indicating that the growth of post-kinematic minerals followed almost instantaneously the termination of deformation. As a consequence, the age of phengites overprinting the mylonitic foliation yields a precise age for the termination of deformation. The spread in age variation of phengites goes together with a spread in Si content, consequently the postkinematic phengites have a higher Si content compared to the overprinted syn-kinematic ones. Therefore the metamorphic pressure conditions of the post-kinematic phengites were lower, indicating continuous deformation during exhumation within a time interval of approximately 12 Ma. We interpret these ages as formation ages during or after shearing, respectively. Muscovite blasts of the undeformed sample yield age values varying between 22 and 34 Ma. We interpret these ages as cooling ages, following the metamorphic peak temperatures. To conclude, sinistral shear in the western TW started at least 24 Ma ago and terminated at 12 Ma. Therefore, these shear zones do not predate dextral displacements or lateral extrusion within the eastern Tauern sub-dome, which are also Miocene (Inger & Cliff, 1994, Frisch et al., 1998, Glodny et al., 2008). This conclusion suggests that they formed as part of an orogen-scale conjugate system, accommodating Miocene shortening due to South-Alpine indentation. Since these shear zones are transpressive, showing a component of vertical displacement, their age may also constrain exhumation of the Tauern dome.
NASA Astrophysics Data System (ADS)
Chinn, L.; Blythe, A. E.; Fendick, A.
2012-12-01
New apatite fission-track ages show varying rates of vertical exhumation at the eastern terminus of the Garlock fault zone. The Garlock fault zone is a 260 km long east-northeast striking strike-slip fault with as much as 64 km of sinistral offset. The Garlock fault zone terminates in the east in the Avawatz Mountains, at the intersection with the dextral Southern Death Valley fault zone. Although motion along the Garlock fault west of the Avawatz Mountains is considered purely strike-slip, uplift and exhumation of bedrock in the Avawatz Mountains south of the Garlock fault, as recently as 5 Ma, indicates that transpression plays an important role at this location and is perhaps related to a restricting bend as the fault wraps around and terminates southeastward along the Avawatz Mountains. In this study we complement extant thermochronometric ages from within the Avawatz core with new low temperature fission-track ages from samples collected within the adjacent Garlock and Southern Death Valley fault zones. These thermochronometric data indicate that vertical exhumation rates vary within the fault zone. Two Miocene ages (10.2 (+5.0/-3.4) Ma, 9.0 (+2.2/-1.8) Ma) indicate at least ~3.3 km of vertical exhumation at ~0.35 mm/yr, assuming a 30°C/km geothermal gradient, along a 2 km transect parallel and adjacent to the Mule Spring fault. An older Eocene age (42.9 (+8.7/-7.3) Ma) indicates ~3.3 km of vertical exhumation at ~0.08 mm/yr. These results are consistent with published exhumation rates of 0.35 mm/yr between ~7 and ~4 Ma and 0.13 mm/yr between ~15 and ~9 Ma, as determined by apatite fission-track and U-Th/He thermochronometry in the hanging-wall of the Mule Spring fault. Similar exhumation rates on both sides of the Mule Spring fault support three separate models: 1) Thrusting is no longer active along the Mule Spring fault, 2) Faulting is dominantly strike-slip at the sample locations, or 3) Miocene-present uplift and exhumation is below detection levels using apatite fission-track thermochronometry. In model #1 slip on the Mule Spring fault may have propagated towards the range front, and may be responsible for the fault-propagation-folding currently observed along the northern branch of the Southern Death Valley fault zone. Model #2 may serve to determine where faulting has historically included a component of thrust faulting to the east of sample locations. Model #3 would further determine total offset along the Mule Spring fault from Miocene-present. Anticipated fission-track and U-Th/He data will help distinguish between these alternative models.
NASA Astrophysics Data System (ADS)
Scudiero, Elia; Skaggs, Todd; Anderson, Ray; Corwin, Dennis
2016-04-01
Irrigation in California's Central Valley (USA) has decreased significantly due to water shortages resulting from the current drought, which began in 2010. In particular, fallow fields in the west side of the San Joaquin Valley (WSJV), which is the southwest portion of the Central Valley, increased from around 12% in the years before the drought (2007-2010) to 20-25% in the following years (2011-2015). We monitored and mapped drought-induced edaphic changes in salinity at two scales: (i) field scale (32.4-ha field in Kings County) and (ii) water district scale (2400 ha at -former- Broadview Water District in Fresno County). At both scales drought-induced land-use changes (i.e., shift from irrigated agriculture to fallow) drastically decreased soil quality by increasing salinity (and sodicity), especially in the root-zone (top 1.2 m). The field study monitors the spatial (three dimensions) changes of soil salinity (and sodicity) in the root-zone during 10 years of irrigation with drainage water followed by 4 years of no applied irrigation water (only rainfall) due to drought conditions. Changes of salinity (and other edaphic properties), through the soil profile (down to 1.2 m, at 0.3-m increments), were monitored and modeled using geospatial apparent electrical conductivity measurements and extensive soil sampling in 1999, 2002, 2004, 2009, 2011, and 2013. Results indicate that when irrigation was applied, salts were leached from the root-zone causing a remarkable improvement in soil quality. However, in less than two years after termination of irrigation, salinity in the soil profile returned to original levels or higher across the field. At larger spatial scales the effect of drought-induced land-use change on root-zone salinity is also evident. Up to spring 2006, lands in Broadview Water District (BWD) were used for irrigated agriculture. Water rights were then sold and the farmland was retired. Soil quality decreased since land retirement, especially during the drought years. Root-zone soil salinity was mapped in 1991 using geospatial apparent electrical conductivity measurements and extensive soil sampling and in 2013 using recent root-zone remote sensing salinity map for the WSJV (developed and published by the U.S. Salinity Laboratory, USDA-ARS), which was calibrated and (independently) validated, including fields from the BWD. Results reveal dramatic increases in soil salinity for all the fields that were originally non-saline and slightly-saline in 1991. Additionally, time-series analysis of very-high resolution ortho-imagery (from Google Earth and USGS) suggests that surface soil quality drastically decreased especially during the drought years. Our research shows how terminating irrigation in California's Central Valley can lead to substantial soil salinization in a very short time. Salinization in WSJV due to the termination of irrigation is a consequence of the complex multi-scale interaction of geomorphologic, topographic, and anthropogenic factors requiring yearly monitoring to adequately assess the impacts of drought for use in field- and basin-scale water management decisions. Among other concerns, increased salinity and sodicity affect vegetation growth and may lead to increased soil erosion and very-fine dust formation creating health and environmental hazards.
The continuation of the Kazerun fault system across the Sanandaj-Sirjan zone (Iran)
NASA Astrophysics Data System (ADS)
Safaei, Homayon
2009-08-01
The Kazerun (or Kazerun-Qatar) fault system is a north-trending dextral strike-slip fault zone in the Zagros mountain belt of Iran. It probably originated as a structure in the Panafrican basement. This fault system played an important role in the sedimentation and deformation of the Phanerozoic cover sequence and is still seismically active. No previous studies have reported the continuation of this important and ancient fault system northward across the Sanandaj-Sirjan zone. The Isfahan fault system is a north-trending dextral strike-slip fault across the Sanandaj-Sirjan zone that passes west of Isfahan city and is here recognized for the first time. This important fault system is about 220 km long and is seismically active in the basement as well as the sedimentary cover sequence. This fault system terminates to the south near the Main Zagros Thrust and to the north at the southern boundary of the Urumieh-Dokhtar zone. The Isfahan fault system is the boundary between the northern and southern parts of Sanandaj-Sirjan zone, which have fundamentally different stratigraphy, petrology, geomorphology, and geodynamic histories. Similarities in the orientations, kinematics, and geologic histories of the Isfahan and Kazerun faults and the way they affect the magnetic basement suggest that they are related. In fact, the Isfahan fault is a continuation of the Kazerun fault across the Sanandaj-Sirjan zone that has been offset by about 50 km of dextral strike-slip displacement along the Main Zagros Thrust.
Active zone density is conserved during synaptic growth but impaired in aged mice
Chen, Jie; Mizushige, Takafumi; Nishimune, Hiroshi
2013-01-01
Presynaptic active zones are essential structures for synaptic vesicle release, but the developmental regulation of their number and maintenance during aging at mammalian neuromuscular junctions (NMJs) remains unknown. Here, we analyzed the distribution of active zones in developing, mature, and aged mouse NMJs by immunohistochemical detection of the active zone-specific protein Bassoon. Bassoon is a cytosolic scaffolding protein essential for the active zone assembly in ribbon synapses and some brain synapses. Bassoon staining showed a punctate pattern in nerve terminals and axons at the nascent NMJ on embryonic days 16.5–18.5. Three-dimensional reconstruction of NMJs revealed that the majority of Bassoon puncta within an NMJ were attached to the presynaptic membrane from postnatal day 0 to adulthood, and colocalized with another active zone protein Piccolo. During postnatal development, the number of Bassoon puncta increased as the size of the synapses increased. Importantly, the density of Bassoon puncta remained relatively constant from postnatal day 0 to 54 at 2.3 puncta/μm2, while the synapse size increased 3.3-fold. However, Bassoon puncta density and signal intensity were significantly attenuated at the NMJs of 27-month-old aged mice. These results suggest that synapses maintain the density of synaptic vesicle release sites while the synapse size changes, but this density becomes impaired during aging. PMID:21935939
Localized sulfate-reducing zones in a coastal plain aquifer
Brown, C.J.; Coates, J.D.; Schoonen, M.A.A.
1999-01-01
High concentrations of dissolved iron in ground water of coastal plain or alluvial aquifers contribute to the biofouling of public supply wells for which treatment and remediation is costly. Many of these aquifers, however, contain zones in which microbial sulfate reduction and the associated precipitation of iron-sulfide minerals decreases iron mobility. The principal water-bearing aquifer (Magothy Aquifer of Cretaceous age) in Suffolk County, New York, contains localized sulfate-reducing zones in and near lignite deposits, which generally are associated with clay lenses. Microbial analyses of core samples amended with [14C]-acetate indicate that microbial sulfate reduction is the predominant terminal-electron-accepting process (TEAP) in poorly permeable, lignite-rich sediments at shallow depths and near the ground water divide. The sulfate-reducing zones are characterized by abundant lignite and iron-sulfide minerals, low concentrations of Fe(III) oxyhydroxides, and by proximity to clay lenses that contain pore water with relatively high concentrations of sulfate and dissolved organic carbon. The low permeability of these zones and, hence, the long residence time of ground water within them, permit the preservation and (or) allow the formation of iron-sulfide minerals, including pyrite and marcasite. Both sulfate-reducing bacteria (SRB) and iron-reducing bacteria (IRB) are present beneath and beyond the shallow sulfate-reducing zones. A unique Fe(III)-reducing organism, MD-612, was found in core sediments from a depth of 187 m near the southern shore of Long Island. The distribution of poorly permeable, lignite-rich, sulfate-reducing zones with decreased iron concentration is varied within the principal aquifer and accounts for the observed distribution of dissolved sulfate, iron, and iron sulfides in the aquifer. Locating such zones for the placement of production wells would be difficult, however, because these zones are of limited aerial extent.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Briggs, Brandon R; Graw, Michael; Brodie, Eoin L
2013-11-01
The biogeochemical processes that occur in marine sediments on continental margins are complex; however, from one perspective they can be considered with respect to three geochemical zones based on the presence and form of methane: sulfate–methane transition (SMTZ), gas hydrate stability zone (GHSZ), and free gas zone (FGZ). These geochemical zones may harbor distinct microbial communities that are important in biogeochemical carbon cycles. The objective of this study was to describe the microbial communities in sediments from the SMTZ, GHSZ, and FGZ using molecular ecology methods (i.e. PhyloChip microarray analysis and terminal restriction fragment length polymorphism (T-RFLP)) and examining themore » results in the context of non-biological parameters in the sediments. Non-metric multidimensional scaling and multi-response permutation procedures were used to determine whether microbial community compositions were significantly different in the three geochemical zones and to correlate samples with abiotic characteristics of the sediments. This analysis indicated that microbial communities from all three zones were distinct from one another and that variables such as sulfate concentration, hydrate saturation of the nearest gas hydrate layer, and depth (or unmeasured variables associated with depth e.g. temperature, pressure) were correlated to differences between the three zones. The archaeal anaerobic methanotrophs typically attributed to performing anaerobic oxidation of methane were not detected in the SMTZ; however, the marine benthic group-B, which is often found in SMTZ, was detected. Within the GHSZ, samples that were typically closer to layers that contained higher hydrate saturation had indicator sequences related to Vibrio-type taxa. These results suggest that the biogeographic patterns of microbial communities in marine sediments are distinct based on geochemical zones defined by methane.« less
Clarke, John S.; Hamrick, Michael D.; Holloway, O. Gary
2011-01-01
Borehole geophysical logs and flowmeter data were collected in April 2011 from eight boreholes to identify the depth and orientation of cavernous zones within the Miocene Tampa Limestone in the vicinity of Jim Woodruff Lock and Dam in Jackson County, Florida. These data are used to assess leakage near the dam. Each of the eight boreholes was terminated in limestone at depths ranging from 84 to 104 feet. Large cavernous zones were encountered in most of the borings, with several exceeding 20-inches in diameter. The cavernous zones generally were between 1 and 5 feet in height, but a cavern in one of the borings reached a height of about 6 feet. The resistivity of limestone layers penetrated by the boreholes generally was less than 1,000 ohm-meters. Formation resistivity near the cavernous zones did not show an appreciable contrast from surrounding bedrock, probably because the bedrock is saturated, owing to its primary permeability. Measured flow rates in the eight boreholes determined using an electromagnetic flowmeter were all less than ±0.1 liter per second. These low flow rates suggest that vertical hydraulic gradients in the boreholes are negligible and that hydraulic head in the various cavernous zones shows only minor, if any, variation.
Cunningham, Kevin J.
2015-01-01
In addition to the preceding seismic-reflection analysis, interpretation of geophysical well log data from four effluent injection wells at the North District “Boulder Zone” Well Field delineated a narrow karst collapse structure beneath the injection facility that extends upward about 900 ft from the top of the Boulder Zone to about 125 ft above the top of the uppermost major permeable zone of the Lower Floridan aquifer. No karst collapse structures were identified in the seismic-reflection profiles acquired near the North District “Boulder Zone” Well Field. However, karst collapse structures at the level of the lowermost major permeable zone of the Lower Floridan aquifer at the South District “Boulder Zone” Well Field are present at three locations, as indicated by seismic-reflection data acquired in the C–1 Canal bordering the south side of the injection facility. Results from the North District “Boulder Zone” Well Field well data indicate that a plausible hydraulic connection between faults and stratiform permeability zones may contribute to the upward transport of effluent, terminating above the base of the deepest U.S. Environmental Protection Agency designated underground source of drinking water at the North District “Boulder Zone” Well Field.
Engineered and subsequent intrinsic in situ bioremediation of a diesel fuel contaminated aquifer
NASA Astrophysics Data System (ADS)
Hunkeler, Daniel; Höhener, Patrick; Zeyer, Josef
2002-12-01
A diesel fuel contaminated aquifer in Menziken, Switzerland was treated for 4.5 years by injecting aerated groundwater, supplemented with KNO 3 and NH 4H 2PO 4 to stimulate indigenous populations of petroleum hydrocarbon (PHC) degrading microorganisms. After dissolved PHC concentrations had stabilized at a low level, engineered in situ bioremediation was terminated. The main objective of this study was to evaluate the efficacy of intrinsic in situ bioremediation as a follow-up measure to remove PHC remaining in the aquifer after terminating engineered in situ bioremediation. In the first 7 months of intrinsic in situ bioremediation, redox conditions in the source area became more reducing as indicated by lower concentrations of SO 42- and higher concentrations of Fe(II) and CH 4. In the core of the source area, strongly reducing conditions prevailed during the remaining study period (3 years) and dissolved PHC concentrations were higher than during engineered in situ bioremediation. This suggests that biodegradation in the core zone was limited by the availability of oxidants. In lateral zones of the source area, however, gradually more oxidized conditions were reestablished again, suggesting that PHC availability increasingly limited biodegradation. The total DIC production rate in the aquifer decreased within 2 years to about 25% of that during engineered in situ bioremediation and remained at that level. Stable carbon isotope analysis confirmed that the produced DIC mainly originated from PHC mineralization. The total rate of DIC and CH 4 production in the source area was more than 300 times larger than the rate of PHC elution. This indicates that biodegradation coupled to consumption of naturally occurring oxidants was an important process for removal of PHC which remained in the aquifer after terminating engineered measures.
2014-03-27
asymptotically equal. Carlsson shows that the problem is solved by treating each subregion Ri as a traveling salesman problem (TSP) with a set of points that...terminal state to the goal. If no- travel zones are repre- sented as the union of regions Akx > Bk, the coverage problem can be expressed as an IP [14...3 1.2 Problem Statement
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-24
... FR 1170, 01/12/2009; correction 74 FR 3987, 01/22/2009; 75 FR 71069- 71070, 11/22/2010) as an option... magnet sites, existing Site 8 would be categorized as a usage-driven site, Sites 3, 4, 6, 7, 12 and 13... 30, 2017, and to a three-year sunset provision for usage-driven sites that would terminate authority...
NASA Astrophysics Data System (ADS)
Closson, D.; Abou Karaki, N.; Milisavljevic, N.; Pasquali, P.; Holecz, F.; Bouaraba, A.
2012-04-01
For several decades, surface water and groundwater located in the closed Dead Sea basin experience excessive exploitation. In fifty years, the level of the terminal lake has fallen by about 30 meters and its surface shrunk by one third. The coastal zone is the one that best shows the stigma of the general environmental degradation. Among these are the sinkholes, landslides and subsidence. For years, these phenomena are relatively well documented, particularly sinkholes and subsidence. Over the past five years, field observations combined with ground deformations measurements by radar interferometric stacking techniques have shown that the intensity (size, frequency) of the collapses is increasing in the most affected part of the southern Dead Sea area. The zones of the dried up Lynch Strait, the Lisan peninsula and Ghor Al Haditha in Jordan seem the most affected. Very high resolution (0.5 to 2 m) GeoEye satellite images have shown that many sinkholes also formed below the level of the Dead Sea. The water transparency allows observations up to several meters deep. These data contribute to the validation of the models developed in connection with the deformation of the fresh/saline water interface due to an imbalance always more pronounced between the levels of the surrounding groundwaters and of the terminal lake.
Sukehiro, Nayu; Kida, Nori; Umezawa, Masahiro; Murakami, Takayuki; Arai, Naoko; Jinnai, Tsunesada; Inagaki, Shunichi; Tsuchiya, Hidetoshi; Maruyama, Hiroshi; Tsuda, Yoshio
2013-01-01
The invasion of the yellow fever mosquito Aedes aegypti at Narita International Airport, Japan was detected for the first time. During the course of routine vector surveillance at Narita International Airport, 27 Ae. aegypti adults emerged from larvae and pupae collected from a single larvitrap placed near No. 88 spot at passenger terminal 2 on August 8, 2012. After the appearance of Ae. aegypti in the larvitrap, we defined a 400-m buffer zone and started an intensive vector survey using an additional 34 larvitraps and 15 CO2 traps. International aircraft and passenger terminal 2 were also inspected, and one Ae. aegypti male was collected from the cargo space of an international aircraft from Darwin via Manila on August 28, 2012. Larvicide treatment with 1.5% fenitrothion was conducted in 64 catch basins and one ditch in the 400-m buffer zone. Twenty-four large water tanks were also treated at least once with 0.5% pyriproxyfen, an insect growth regulator. No Ae. aegypti eggs or adults were found during the 1-month intensive vector survey after finding larvae and pupae in the larvitrap. We concluded that Ae. aegypti had failed to establish a population at Narita International Airport.
NASA Technical Reports Server (NTRS)
Barraclough, D. R.; Hide, R.; Leaton, B. R.; Lowes, F. J.; Malin, S. R. C.; Wilson, R. L. (Principal Investigator)
1982-01-01
Progress in the harmonic analysis of MAGSAT data is reported. Single-day data sets were subdivided into information on the sunrise side of the Earth and information on the sunset side of the Earth. Data for the main and external fields each demonstrate a clear and consistent systematic difference between the sets of data which was determined to be, due to ionospheric currents which differ from the sunset to the sunrise terminator. A toroidal field was analyzed for and determined to be an apparent toroidal field resulting from electric currents concentrated in the two terminators. Progressive elimination of auroral zone data demonstrates that the information presented does not arise from complications due to Birkeland currents.
The mode 3 crack problem in bonded materials with a nonhomogeneous interfacial zone
NASA Technical Reports Server (NTRS)
Erdogan, Fazil; Kaya, A. C.; Joseph, P. F.
1988-01-01
The mode 3 crack problem for two bonded homogeneous half planes was considered. The interfacial zone was modelled by a nonhomogeneous strip in such a way that the shear modulus is a continuous function throughout the composite medium and has discontinuous derivatives along the boundaries of the interfacial zone. The problem was formulated for cracks perpendicular to the nominal interface and was solved for various crack locations in and around the interfacial region. The asymptotic stress field near the tip of a crack terminating at an interface was examined and it was shown that, unlike the corresponding stress field in piecewise homogeneous materials, in this case the stresses have the standard square root singularity and their angular variation was identical to that of a crack in a homogeneous medium. With application to the subcritical crack growth process in mind, the results given include mostly the stress intensity factors for some typical crack geometries and various material combinations.
The mode III crack problem in bonded materials with a nonhomogeneous interfacial zone
NASA Technical Reports Server (NTRS)
Erdogan, F.; Joseph, P. F.; Kaya, A. C.
1991-01-01
The mode 3 crack problem for two bonded homogeneous half planes was considered. The interfacial zone was modelled by a nonhomogeneous strip in such a way that the shear modulus is a continuous function throughout the composite medium and has discontinuous derivatives along the boundaries of the interfacial zone. The problem was formulated for cracks perpendicular to the nominal interface and was solved for various crack locations in and around the interfacial region. The asymptotic stress field near the tip of a crack terminating at an interface was examined and it was shown that, unlike the corresponding stress field in piecewise homogeneous materials, in this case the stresses have the standard square root singularity and their angular variation was identical to that of a crack in a homogeneous medium. With application to the subcritical crack growth process in mind, the results given include mostly the stress intensity factors for some typical crack geometries and various material combinations.
Amarouche, Nassima; Boudesocque, Leslie; Borie, Nicolas; Giraud, Matthieu; Forni, Luciano; Butte, Alessandro; Edwards, Florence; Renault, Jean-Hugues
2014-06-01
A new type 1 ternary biphasic system composed of cyclopentyl methyl ether, dimethylformamide and water was developed, characterized and successfully used for the purification of a lipophilic, protected peptide by pH-zone refining centrifugal partition chromatography. The protected peptide is an 8-mer, key intermediate in bivalirudin (Angiomax®) synthesis and shows a very low solubility in the solvents usually used in liquid chromatography. All ionic groups, except the N-terminal end of the peptide, are protected by a benzyl group. The purification of this peptide was achieved with a purity of about 99.04% and a recovery of 94% using the new ternary biphasic system cyclopentyl methyl ether/dimethylformamide/water (49:40:11, v/v) in the descending pH-zone refining mode with triethylamine (28 mM) as the retainer and methanesulfonic acid (18 mM) as the eluter. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Modeling and simulation of the debonding process of composite solid propellants
NASA Astrophysics Data System (ADS)
Feng, Tao; Xu, Jin-sheng; Han, Long; Chen, Xiong
2017-07-01
In order to study the damage evolution law of composite solid propellants, the molecular dynamics particle filled algorithm was used to establish the mesoscopic structure model of HTPB(Hydroxyl-terminated polybutadiene) propellants. The cohesive element method was employed for the adhesion interface between AP(Ammonium perchlorate) particle and HTPB matrix and the bilinear cohesive zone model was used to describe the mechanical response of the interface elements. The inversion analysis method based on Hooke-Jeeves optimization algorithm was employed to identify the parameters of cohesive zone model(CZM) of the particle/binder interface. Then, the optimized parameters were applied to the commercial finite element software ABAQUS to simulate the damage evolution process for AP particle and HTPB matrix, including the initiation, development, gathering and macroscopic crack. Finally, the stress-strain simulation curve was compared with the experiment curves. The result shows that the bilinear cohesive zone model can accurately describe the debonding and fracture process between the AP particles and HTPB matrix under the uniaxial tension loading.
The GRO remote terminal system
NASA Technical Reports Server (NTRS)
Zillig, David J.; Valvano, Joe
1994-01-01
In March 1992, NASA HQ challenged GSFC/Code 531 to propose a fast, low-cost approach to close the Tracking Data Relay Satellite System (TDRSS) Zone-of-Exclusion (ZOE) over the Indian Ocean in order to provide global communications coverage for the Compton Gamma Ray Observatory (GRO) spacecraft. GRO had lost its tape recording capability which limited its valuable science data return to real-time contacts with the TDRS-E and TDRS-W synchronous data relay satellites, yielding only approximately 62 percent of the possible data obtainable. To achieve global coverage, a TDRS spacecraft would have to be moved over the Indian Ocean out of line-of-sight control of White Sands Ground Terminal (WSGT). To minimize operations life cycle costs, Headquarters also set a goal for remote control, from the WSGT, of the overseas ground station which was required for direct communications with TDRS-1. On August 27, 1992, Code 531 was given the go ahead to implement the proposed GRO Relay Terminal System (GRTS). This paper describes the Remote Ground Relay Terminal (RGRT) which went operational at the Canberra Deep Space Communications Complex (CDSCC) in Canberra, Australia in December 1993 and is currently augmenting the TDRSS constellation in returning between 80-100 percent of GRO science data under the control of a single operator at WSGT.
Sinclair-Davis, Amy N; McAllaster, Michael R; de Graffenried, Christopher L
2017-11-15
The parasite Trypanosoma brucei is highly polarized, including a flagellum that is attached along the cell surface by the flagellum attachment zone (FAZ). During cell division, the new FAZ positions the cleavage furrow, which ingresses from the anterior tip of the cell towards the posterior. We recently identified TOEFAZ1 (for 'Tip of the Extending FAZ protein 1') as an essential protein in trypanosome cytokinesis. Here, we analyzed the localization and function of TOEFAZ1 domains by performing overexpression and RNAi complementation experiments. TOEFAZ1 comprises three domains with separable functions: an N-terminal α-helical domain that may be involved in FAZ recruitment, a central intrinsically disordered domain that keeps the morphogenic kinase TbPLK at the new FAZ tip, and a C-terminal zinc finger domain necessary for TOEFAZ1 oligomerization. Both the N-terminal and C-terminal domains are essential for TOEFAZ1 function, but TbPLK retention at the FAZ is not necessary for cytokinesis. The feasibility of alternative cytokinetic pathways that do not employ TOEFAZ1 are also assessed. Our results show that TOEFAZ1 is a multimeric scaffold for recruiting proteins that control the timing and location of cleavage furrow ingression. © 2017. Published by The Company of Biologists Ltd.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pazehoski, Kristina O., E-mail: pazehosk@pitt.edu; Cobine, Paul A., E-mail: pac0006@auburn.edu; Winzor, Donald J.
2011-03-11
Research highlights: {yields} A metal-binding protein domain is directly involved in protein dimerization. {yields} Fusing the metal-binding domain to a monomeric protein induces dimerization. {yields} Frontal size-exclusion chromatography measures the strength of dimer interaction. {yields} Ultracentrifugation studies confirm the influence of metal binding on dimerization. -- Abstract: Metal binding to the C-terminal region of the copper-responsive repressor protein CopY is responsible for homodimerization and the regulation of the copper homeostasis pathway in Enterococcus hirae. Specific involvement of the 38 C-terminal residues of CopY in dimerization is indicated by zonal and frontal (large zone) size-exclusion chromatography studies. The studies demonstrate thatmore » the attachment of these CopY residues to the immunoglobulin-binding domain of streptococcal protein G (GB1) promotes dimerization of the monomeric protein. Although sensitivity of dimerization to removal of metal from the fusion protein is smaller than that found for CopY (as measured by ultracentrifugation studies), the demonstration that an unrelated protein (GB1) can be induced to dimerize by extending its sequence with the C-terminal portion of CopY confirms the involvement of this region in CopY homodimerization.« less
Farnum, C E; Turgai, J; Wilsman, N J
1990-09-01
The functional unit within the growth plate consists of a column of chondrocytes that passes through a sequence of phases including proliferation, hypertrophy, and death. It is important to our understanding of the biology of the growth plate to determine if distal hypertrophic cells are viable, highly differentiated cells with the potential of actively controlling terminal events of endochondral ossification prior to their death at the chondro-osseous junction. This study for the first time reports on the visualization of living hypertrophic chondrocytes in situ, including the terminal hypertrophic chondrocyte. Chondrocytes in growth plate explants are visualized using rectified differential interference contrast microscopy. We record and measure, using time-lapse cinematography, the rate of movement of subcellular organelles at the limit of resolution of this light microscopy system. Control experiments to assess viability of hypertrophic chondrocytes include coincubating organ cultures with the intravital dye fluorescein diacetate to assess the integrity of the plasma membrane and cytoplasmic esterases. In this system, all hypertrophic chondrocytes, including the very terminal chondrocyte, exist as rounded, fully hydrated cells. By the criteria of intravital dye staining and organelle movement, distal hypertrophic chondrocytes are identical to chondrocytes in the proliferative and early hypertrophic cell zones.
NASA Astrophysics Data System (ADS)
Lücke, O. H.; Arroyo, I. G.
2015-07-01
The eastern part of the oceanic Cocos Plate presents a heterogeneous crustal structure due to diverse origins and ages as well as plate-hot spot interactions which originated the Cocos Ridge, a structure that converges with the Caribbean Plate in southeastern Costa Rica. The complex structure of the oceanic plate directly influences the dynamics and geometry of the subduction zone along the Middle American Trench. In this paper an integrated interpretation of the slab geometry is presented based on three-dimensional density modeling of combined satellite and surface gravity data, constrained by available geophysical and geological data and seismological information obtained from local networks. The results show the continuation of steep subduction geometry from the Nicaraguan margin into Northwestern Costa Rica, followed by a moderate dipping slab under the Central Cordillera toward the end of the Central American Volcanic Arc. To the southeast end of the volcanic arc, our preferred model shows a steep, coherent slab that extends up to the landward projection of the Panama Fracture Zone. Overall, a gradual change in the depth of the intraplate seismicity is observed, reaching 220 km in the northwestern part, and becoming progressively shallower toward the southeast, where it reaches a terminal depth of 75 km. The changes in the terminal depth of the observed seismicity correlate with the increased density in the modeled slab. The absence of intermediate depth intraplate seismicity in the southeastern section and the higher densities for the subducted slab in this area, support a model in which dehydration reactions in the subducted slab cease at a shallower depth, originating an anhydrous and thus aseismic slab.
Aerobic Microbial Respiration In Oceanic Oxygen Minimum Zones.
Kalvelage, Tim; Lavik, Gaute; Jensen, Marlene M; Revsbech, Niels Peter; Löscher, Carolin; Schunck, Harald; Desai, Dhwani K; Hauss, Helena; Kiko, Rainer; Holtappels, Moritz; LaRoche, Julie; Schmitz, Ruth A; Graco, Michelle I; Kuypers, Marcel M M
2015-01-01
Oxygen minimum zones are major sites of fixed nitrogen loss in the ocean. Recent studies have highlighted the importance of anaerobic ammonium oxidation, anammox, in pelagic nitrogen removal. Sources of ammonium for the anammox reaction, however, remain controversial, as heterotrophic denitrification and alternative anaerobic pathways of organic matter remineralization cannot account for the ammonium requirements of reported anammox rates. Here, we explore the significance of microaerobic respiration as a source of ammonium during organic matter degradation in the oxygen-deficient waters off Namibia and Peru. Experiments with additions of double-labelled oxygen revealed high aerobic activity in the upper OMZs, likely controlled by surface organic matter export. Consistently observed oxygen consumption in samples retrieved throughout the lower OMZs hints at efficient exploitation of vertically and laterally advected, oxygenated waters in this zone by aerobic microorganisms. In accordance, metagenomic and metatranscriptomic analyses identified genes encoding for aerobic terminal oxidases and demonstrated their expression by diverse microbial communities, even in virtually anoxic waters. Our results suggest that microaerobic respiration is a major mode of organic matter remineralization and source of ammonium (~45-100%) in the upper oxygen minimum zones, and reconcile hitherto observed mismatches between ammonium producing and consuming processes therein.
Aerobic Microbial Respiration In Oceanic Oxygen Minimum Zones
Kalvelage, Tim; Lavik, Gaute; Jensen, Marlene M.; Revsbech, Niels Peter; Löscher, Carolin; Schunck, Harald; Desai, Dhwani K.; Hauss, Helena; Kiko, Rainer; Holtappels, Moritz; LaRoche, Julie; Schmitz, Ruth A.; Graco, Michelle I.; Kuypers, Marcel M. M.
2015-01-01
Oxygen minimum zones are major sites of fixed nitrogen loss in the ocean. Recent studies have highlighted the importance of anaerobic ammonium oxidation, anammox, in pelagic nitrogen removal. Sources of ammonium for the anammox reaction, however, remain controversial, as heterotrophic denitrification and alternative anaerobic pathways of organic matter remineralization cannot account for the ammonium requirements of reported anammox rates. Here, we explore the significance of microaerobic respiration as a source of ammonium during organic matter degradation in the oxygen-deficient waters off Namibia and Peru. Experiments with additions of double-labelled oxygen revealed high aerobic activity in the upper OMZs, likely controlled by surface organic matter export. Consistently observed oxygen consumption in samples retrieved throughout the lower OMZs hints at efficient exploitation of vertically and laterally advected, oxygenated waters in this zone by aerobic microorganisms. In accordance, metagenomic and metatranscriptomic analyses identified genes encoding for aerobic terminal oxidases and demonstrated their expression by diverse microbial communities, even in virtually anoxic waters. Our results suggest that microaerobic respiration is a major mode of organic matter remineralization and source of ammonium (~45-100%) in the upper oxygen minimum zones, and reconcile hitherto observed mismatches between ammonium producing and consuming processes therein. PMID:26192623
NASA Technical Reports Server (NTRS)
Abrams, Michael; Verosub, Ken; Finnerty, Tony; Brady, Roland
1987-01-01
The Garlock and Death Valley fault zones in SE California are two active strike-slip faults coming together on the east side of the Avawatz Mtns. The kinematics of this intersection, and the possible continuation of either fault zone, are being investigated using a combination of field mapping, and processing and interpretation of remotely sensed image data. Regional and local relationships are derivable from Thematic Mapper data (30 m resolution), including discrimination and relative age dating of alluvial fans, bedrock mapping, and fault mapping. Aircraft data provide higher spatial resolution over more limited areas. Hypotheses being considered are: (1) the Garlock fault extends east of the intersection; (2) the Garlock fault terminates at the intersection and the Death Valley fault continues southeastward; and (3) the Garlock fault has been offset right laterally by the Death Valley fault which continues to the southeast. Preliminary work indicates that the first hypothesis is invalid. From kinematic considerations, image analysis, and field work the third hypothesis is favored. The projected continuation of the Death Valley zone defines the boundary between the Mojave crustal block and the Basin and Range block.
Effect of concentration and temperature on the rheological behavior of collagen solution.
Lai, Guoli; Li, Yang; Li, Guoying
2008-04-01
Dynamic viscoelastic properties of collagen solutions with concentrations of 0.5-1.5% (w/w) were characterized by means of oscillatory rheometry at temperatures ranging from 20 to 32.5 degrees C. All collagen solutions showed a shear-thinning flow behavior. The complex viscosity exhibited an exponential increase and the loss tangent decreased with the increase of collagen concentration (C(COL)) when the C(COL)> or =0.75%. Both storage modulus (G') and loss modulus (G'') increased with the increase of frequency and concentration, but decreased with the increase of temperature and behaved without regularity at 32.5 degrees C. The relaxation times decreased with the increase of temperature for 1.0% collagen solution. According to a three-zone model, dynamic modulus of collagen solutions showed terminal-zone and plateau-zone behavior when C(COL) was no more than 1.25% or the stated temperature was no more than 30 degrees C. The concentrated solution (1.5%) behaved being entirely in plateau zone. An application of the time-temperature superposition (TTS) allowed the construction of master curve and an Arrhenius-type TTS principle was used to yield the activation energy of 161.4 kJ mol(-1).
NASA Technical Reports Server (NTRS)
Ross, Muriel D.; Chee, Oliver; Black, Samuel; Cutler, Lynn
1991-01-01
Cupric ion-ferricyanide labeling methods and related ferrocyanide-stained tissues were used to locate the characterize, at the ultrastructural level, presumptive impulse initiation zones in the three types of vestibular macular nerve fibers. Large-diameter, M-type vestibular nerve fibers terminate in a calyx at the heminode, and labeling is coextensive with the base of the calyx. Intermediate, M/U-type nerve fibers have short, unmyelinated preterminal segments that sometimes bifurcate intamacularly, and small-diameter, U-type nerve fibers have long, unmyelinated preterminal axons and up to three branches. Preterminals of these nerve fibers display ultrastructural heterogeneity that is correlated with labeling patterns for sodium channels and/or associated polyanionic sites. They have a nodelike ultrastructure and label heavily from near the heminode to the base of the macula. Their intramacular branches, less organized ultrastructurally, label only slightly. Results indicate that vestibular nerve fibers have one impulse initiation zone, located near the heminode, that varies in length according to nerve fiber type. Structural heterogeneity may favor impulse conduction in the central direction, and length of the impulse initiation zone could influence nerve discharge patterns.
Late Devonian conodonts and event stratigraphy in northwestern Algerian Sahara
NASA Astrophysics Data System (ADS)
Mahboubi, Abdessamed; Gatovsky, Yury
2015-01-01
Conodonts recovered from the Late Devonian South Marhouma section comprise 5 genera with 31 species (3 undetermined). The fauna establishes the presence of MN Zones 5, undifferentiated 6/7, 8/10 for the Middle Frasnian, the MN Zones 11, 12, 13 for the Upper Frasnian as well as the Early through Late triangularis Zones in the basal Famennian. The outcropping lithological succession is one of mostly nodular calcilutites alternating with numerous marly and shaly deposits, which, in the lower and upper part, comprise several dysoxic dark shale intervals. Among these the Upper Kellwasser horizon can be precisely dated and as such the presence of the terminal Frasnian Kellwasser Event is recognized for the first time in Algeria. Both the Middlesex and Rhinestreet Events cannot yet be precisely located, but supposedly occur among the dark shale horizons in the lower part of the section. However, their assignment to a precise level has so far not been established. Though poor in conodont abundance the South Marhouma section provides first evidence of the presence of several Montagne Noire conodont zones within the so far widely unstudied Frasnian of the Ougarta Chain. As such it is considered representative for the northwestern Algerian Saoura region.
NASA Astrophysics Data System (ADS)
Momoh, E. I.; Cannat, M.; Singh, S. C.; Watremez, L.; Leroy, S. D.
2016-12-01
Ultra-slow spreading ridges (< 10 mm/yr half-spreading rate), are characterized by a variety of mode accretion, from purely magmatic to nearly amagmatic. With the prevalence of mantle-derived peridotites and sparse volcanism on the seafloor, the easternmost portion of the ultra-slow spreading Southwest Indian Ridge (SWIR) at 64°E represents a melt-poor end-member in the global ridge system. Mantle-derived peridotites there are proposed to have been exhumed along the footwall of detachment faults (Cannat et al, 2006; Sauter et al, 2013). However, the geometry and structural styles of detachments at depth are conjectural. We show the first 3D seismic reflection images of nearly amagmatic axial oceanic lithosphere in this region. The results are from 3D processing of 2D seismic data acquired during the SISMOSMOOTH 2014 cruise along 100 m-spaced profiles in a 1.8 km wide by 24 km long box spanning the axial valley and a part of its elevated northern wall. Wide-angle tomography results from Ocean bottom Seismometer (OBS) line are used to provide a velocity structure of the crust and correlate the MCS reflection images. We image 4 classes of reflectors. The first class occurs in 2 parts as south-dipping events and can be followed in the cross-line of the survey area. The upper part terminates on the northern slope of the massif. The lower part occurs as an isolated event until half of the width of the survey area after which it appears as a continuation of the upper part. This class of reflectors may be due to the damage zone of the active axial detachment fault. The second class of reflectors occurs as north-dipping events. They extend 1 km in the cross-line. They can be interpreted as fractured zones, zones of localized serpentinization or as dikes. The third class of reflectors occurs as sub-horizontal events at depth and seems to serve as the termination of the proposed dikes/fractured zones. On the OBS result, this reflector mimics the 7.5 km/s velocity contour in some areas and < 0.5 s TWT. It is unclear if the depths are coincident. The fourth class of reflectors occurs as shallow intra-crustal reflectors 0.2 - 1 s TWT below the seafloor which does not maintain a consistent character across the survey area. We envisage that they may be associated with zones of localized serpentinization, intrusive melt or fractured zones in the axial valley.
NASA Astrophysics Data System (ADS)
Ott, B.; Mann, P.; Saunders, M.
2013-12-01
Previous workers, mainly mapping onland active faults on Caribbean islands, defined the northern Caribbean plate boundary zone as a 200-km-wide bounded by two active and parallel strike-slip faults: the Oriente fault along the northern edge of the Cayman trough with a GPS rate of 14 mm/yr, and and the Enriquillo-Plaintain Garden fault zone (EPGFZ) with a rate of 5-7 mm/yr. In this study we use 5,000 km of industry and academic data from the Nicaraguan Rise south and southwest of the EPGFZ in the maritime areas of Jamaica, Honduras, and Colombia to define an offshore, 700-km-long, active, left-lateral strike-slip fault in what has previously been considered the stable interior of the Caribbean plate as determined from plate-wide GPS studies. The fault was named by previous workers as the Pedro Banks fault zone because a 100-km-long segment of the fault forms an escarpment along the Pedro carbonate bank of the Nicaraguan Rise. Two fault segments of the PBFZ are defined: the 400-km-long eastern segment that exhibits large negative flower structures 10-50 km in width, with faults segments rupturing the sea floor as defined by high resolution 2D seismic data, and a 300-km-long western segment that is defined by a narrow zone of anomalous seismicity first observed by previous workers. The western end of the PBFZ terminates on a Quaternary rift structure, the San Andres rift, associated with Plio-Pleistocene volcanism and thickening trends indicating initial rifting in the Late Miocene. The southern end of the San Andreas rift terminates on the western Hess fault which also exhibits active strands consistent with left-lateral, strike-slip faults. The total length of the PBFZ-San Andres rift-Southern Hess escarpment fault is 1,200 km and traverses the entire western end of the Caribbean plate. Our interpretation is similar to previous models that have proposed the "stable" western Caribbean plate is broken by this fault whose rate of displacement is less than the threshold recognizable from the current GPS network (~3 mm/yr). The Late Miocene age of the fault indicates it may have activated during the Late Miocene to recent Hispaniola-Bahamas oblique collision event.
Berman, N E; Grant, S
1992-07-01
The callosal connections between visual cortical areas 17 and 18 in adult normally pigmented and "Boston" Siamese cats were studied using degeneration methods, and by transport of WGA-HRP combined with electrophysiological mapping. In normal cats, over 90% of callosal neurons were located in the supragranular layers. The supragranular callosal cell zone spanned the area 17/18 border and extended, on average, some 2-3 mm into both areas to occupy a territory which was roughly co-extensive with the distribution of callosal terminations in these areas. The region of the visual field adjoining the vertical meridian that was represented by neurons in the supragranular callosal cell zone was shown to increase systematically with decreasing visual elevation. Thus, close to the area centralis, receptive-field centers recorded from within this zone extended only up to 5 deg into the contralateral hemifield but at elevations of -10 deg and -40 deg they extended as far as 8 deg and 14 deg, respectively, into this hemifield. This suggests an element of visual non-correspondence in the callosal pathway between these cortical areas, which may be an essential substrate for "coarse" stereopsis at the visual midline. In the Siamese cats, the callosal cell and termination zones in areas 17 and 18 were expanded in width compared to the normal animals, but the major components were less robust. The area 17/18 border was often devoid of callosal axons and, in particular, the number of supragranular layer neurons participating in the pathway were drastically reduced, to only about 25% of those found in the normally pigmented adults. The callosal zones contained representations of the contralateral and ipsilateral hemifields that were roughly mirror-symmetric about the vertical meridian, and both hemifield representations increased with decreasing visual elevation. The extent and severity of the anomalies observed were similar across individual cats, regardless of whether a strabismus was also present. The callosal pathway between these visual cortical areas in the Siamese cat has been considered "silent," since nearly all neurons within its territory are activated only by the contralateral eye. The paucity of supragranular pyramidal neurons involved in the pathway may explain this silence.
Special Effects: Antenna Wetting, Short Distance Diversity and Depolarization
NASA Technical Reports Server (NTRS)
Acosta, Roberto J.
2000-01-01
The Advanced Communication Technology Satellite (ACTS) communications system operates in the Ka frequency band. ACTS uses multiple, hopping, narrow beams and very small aperture terminal (VSAT) technology to establish a system availability of 99.5% for bit-error-rates of 5 x 10(exp -7) Or better over the continental United States. In order maintain this minimum system availability in all US rain zones, ACTS uses an adaptive rain fade compensation protocol to reduce the impact of signal attenuation resulting from propagation effects. The purpose of this paper is to present the results of system and sub-system characterizations considering the statistical effects of system variances due to antenna wetting and depolarization effects. In addition the availability enhancements using short distance diversity in a sub-tropical rain zone are investigated.
NASA Astrophysics Data System (ADS)
Gogacz, A.; Hall, J.; Cifci, G.; Yasar, D.; Kucuk, M.; Yaltirak, C.; Aksu, A.
2009-05-01
The Antalya Basin is one of a series of basins that sweep along the Cyprus Arc in the forearc region between the (formerly) volcanic Tauride Mountains on Turkey in the north and the subduction zone and associated suture between the African plate and the Aegean-Anatolian microplate in the eastern Mediterranean, south of Cyprus. Miocene contraction occurs widely on southwest verging thrusts. Pliocene-Quaternary structures vary from extension/transtension in the northeast, adjacent to the Turkish coastline, to transpression in the southwest, farther offshore. All these structures are truncated at the northwest end of the Antalya Basin by a broad zone of NNE-SSW-trending transverse structure that appears to represent a prolongation of the extreme easterly transform end of the Hellenic arc. Our mapping suggests that this broad zone links the Hellenic Arc with the Isparta Angle in southern Turkey, which we suggest is an earlier location of the junction of Hellenic and Cyprus Arcs: the junction migrated to the southwest over time, as the Hellenic Arc rolled back. The Turkish coastline turns from parallel to the Antalya Basin structures in the east to a N-S orientation, cutting across the trend of the Antalya Basin. The Antalya Complex and the Bey Dağları Mountains provide a spectacular backdrop to this edge of the offshore basin. Somewhere offshore lies the structural termination of the Antalya Basin. In 2001, we acquired around 400 km of high-resolution multi-channel seismic reflection data across the western end of the Antalya Basin to explore the nature of the termination, which we call the Bey Dağları lineament. We present a selection of the seismic profiles with interpretation of the nature and Neogene history of the lineament. Landward of the N-S-trending coastline, ophiolites of the Antalya Complex are exposed in a series of westerly-verging thrust slivers that extend to the carbonate sequences of the Bey Dağları Mountains. Our seismic data indicate that N-S trending west- and east-verging thrusts define a transpressional continental margin. The shelf is underlain by a prominent angular unconformity between overlying shallow-dipping Pliocene-Quaternary sediments and underlying, easterly- dipping ?Miocene sediments.
NASA Astrophysics Data System (ADS)
Scourse, J. D.; Furze, M. F. A.
2001-07-01
In support of their glaciomarine model for the deglaciation of the Irish Sea basin, Eyles and McCabe cited the occurrence of distal glaciomarine mud drapes onshore in the Isles of Scilly and North Devon, and of arctic beach-face gravels and sands around the shores of the Celtic Sea. Glacial and sea-level data from the southern part of the Irish Sea in the terminal zone of the ice stream and the adjacent continental slope are reviewed here to test this aspect of the model. The suggestion that the glacial sequences of both the Isles of Scilly and Fremington in North Devon are glaciomarine mud drapes is rejected. An actively calving tidewater margin only occurred early in the deglacial sequence close to the terminal zone in the south-central Celtic Sea. Relative sea-levels were lower, and therefore glacio-isostatic depression less, than envisaged in the glaciomarine model. Geochronological, sedimentological and biostratigraphical data indicate that the raised beach sequences around the shores of the Celtic Sea and English Channel were deposited at, or during regression soon after, interglacial eustatic highstands. Evidence for ice-rafting at a time of high relative sea-levels is restricted to a phase(s) earlier than the Late Devensian. These data indicate that the raised beach sequences have no bearing on the style of Irish Sea deglaciation.
Chen, Hong; Wang, Haiyang; Liu, Yanfang; Dong, Li
2013-01-01
1. The terminal shoot (or current-year shoot), as one of the most active parts on a woody plant, is a basic unit determining plant height and is potentially influenced by a variety of environmental factors. It has been predicted that tissues amount and their allocation in plant stems may play a critical role in determining plant size in alpine regions. The primary structure in terminal shoots is a key to our understanding treeline formation. The existing theories on treeline formation, however, are still largely lacking of evidence at the species level, much less from anatomy for the terminal shoot. 2. The primary structures within terminal shoot were measured quantitatively for 100 species from four elevation zones along the eastern slope of Gongga Mountain, southwestern China; one group was sampled from above the treeline. An allometric approach was employed to examine scaling relationships interspecifically, and a principal components analysis (PCA) was performed to test the relation among primary xylem, ground tissue, species growth form and altitude. 3. The results showed that xylem tissue size was closely correlated with ground tissue size isometrically across species, while undergoing significant y- or/and x-intercept shift in response to altitudinal belts. Further, a conspicuous characteristic of terminal shoot was its allocation of contrasting tissues between primary xylem and ground tissues with increasing elevation. The result of the PCA showed correlations between anatomical variation, species growth form/height classes and environment. 4. The current study presents a comparative assessment of the allocation of tissue in terminal shoot across phylogenically and ecologically diverse species, and analyzes tissue, function and climate associations with plant growth forms and height classes among species. The interspecific connection between primary xylem ratio and plant size along an elevation gradient suggests the importance of primary xylem in explaining the treeline formation.
Chen, Hong; Wang, Haiyang; Liu, Yanfang; Dong, Li
2013-01-01
1. The terminal shoot (or current-year shoot), as one of the most active parts on a woody plant, is a basic unit determining plant height and is potentially influenced by a variety of environmental factors. It has been predicted that tissues amount and their allocation in plant stems may play a critical role in determining plant size in alpine regions. The primary structure in terminal shoots is a key to our understanding treeline formation. The existing theories on treeline formation, however, are still largely lacking of evidence at the species level, much less from anatomy for the terminal shoot. 2. The primary structures within terminal shoot were measured quantitatively for 100 species from four elevation zones along the eastern slope of Gongga Mountain, southwestern China; one group was sampled from above the treeline. An allometric approach was employed to examine scaling relationships interspecifically, and a principal components analysis (PCA) was performed to test the relation among primary xylem, ground tissue, species growth form and altitude. 3. The results showed that xylem tissue size was closely correlated with ground tissue size isometrically across species, while undergoing significant y- or/and x-intercept shift in response to altitudinal belts. Further, a conspicuous characteristic of terminal shoot was its allocation of contrasting tissues between primary xylem and ground tissues with increasing elevation. The result of the PCA showed correlations between anatomical variation, species growth form/height classes and environment. 4. The current study presents a comparative assessment of the allocation of tissue in terminal shoot across phylogenically and ecologically diverse species, and analyzes tissue, function and climate associations with plant growth forms and height classes among species. The interspecific connection between primary xylem ratio and plant size along an elevation gradient suggests the importance of primary xylem in explaining the treeline formation. PMID:23658621
Stannard, Adam; Morrison, Jonathan J; Sharon, Danny J; Eliason, Jonathan L; Rasmussen, Todd E
2013-08-01
Hemorrhage is a leading cause of death in military and civilian trauma. Despite the importance of the aorta as a site of hemorrhage control and resuscitative occlusion, detailed knowledge of its morphometry is lacking. The objective of this study was to characterize aortic morphometry in a trauma population, including quantification of distances as well as and diameters and definition of relevant aortic zones. Center line measures were made (Volume Viewer) from contrast computed tomography (CT) scans of male trauma patients (18-45 years). Aortic zones were defined based on branch arteries. Zone I includes left subclavian to celiac; Zone II includes celiac to caudal renal; Zone III includes caudal renal to aortic bifurcation. Zone lengths were calculated and correlated to a novel external measure of torso extent (symphysis pubis to sternal notch). Eighty-eight males (mean [SD], 28 [4] years) had CT scans for the study. The median (interquartile range) lengths (mm) of Zones I, II, and III were 210 mm (202-223 mm), 33 mm (28-38 mm), and 97 mm (91-103 mm), respectively. Median aortic diameters at the left subclavian, celiac, and lowest renal arteries were 21 mm (20-23 mm), 18 mm (16-19 mm), and 15 mm (14-16 mm), respectively, and the terminal aortic diameter was 14 mm (13-15 mm). The correlation of determination for descending aortic length (all zones) against torso extend was r = 0.454. This study provides a morphometric analysis of the aorta in a male population, demonstrating consistency of length and diameter while defining distinct axial zones. Findings suggest that center line aortic distances correlate with a simple, external measure of torso extent. Morphometric study of the aorta using CT data may facilitate the development and implementation of occlusion techniques to manage noncompressible torso, pelvic, and junctional femoral hemorrhage.
Cockburn, J F; Maddern, G J; Wemyss-Holden, S A
2007-03-01
To examine the effect of applying increasing amounts of direct current (DC) before and during alternating current radiofrequency ablation of porcine liver. Using a Radiotherapeutics RF3000 generator, a 9 V AC/DC transformer and a 16 G plain aluminium tube as an electrode, a control group of 24 porcine hepatic radiofrequency ablation zones was compared with 24 zones created using a bimodal electric tissue ablation (BETA) technique in three pigs. All ablations were terminated when tissue impedance rose to greater than 999 Omega or radiofrequency energy input fell below 5 W on three successive measurements taken at 1 min intervals. BETA ablations were performed in two phases: an initial phase of variable duration DC followed by a second phase during which standard radiofrequency ablation was applied simultaneously with DC. During this second phase, radiofrequency power input was regulated by the feedback circuitry of the RF3000 generator according to changes in tissue impedance. The diameters (mm) of each ablation zone were measured by two observers in two planes perpendicular to the plane of needle insertion. The mean short axis diameter of each ablation zone was subjected to statistical analysis. With increased duration of prior application of DC, there was a progressive increase in the diameter of the ablation zone (p<0.001). This effect increased sharply up to 300 s of pre-treatment after which a further increase in diameter occurred, but at a much lesser rate. A maximum ablation zone diameter of 32 mm was produced (control diameters 10-13 mm). Applying a 9 V DC to porcine liver in vivo, and continuing this DC application during subsequent radiofrequency ablation, results in larger ablation zone diameters compared with radiofrequency ablation alone.
Distribution and structure of efferent synapses in the chicken retina
Lindstrom, SH; Nacsa, N; Blankenship, T; Fitzgerald, PG; Weller, C; Vaney, DI; Wilson, M
2012-01-01
The visual system of birds includes an efferent projection from a visual area, the isthmooptic nucleus in the midbrain, back to the retina. Using a combination of anterograde labeling of efferent fibers, reconstruction of dye-filled neurons, NADPH-diaphorase staining, and transmission electron microscopy we have examined the distribution of efferent fibers and their synaptic structures in the chicken retina. We show that efferent fibers terminate strictly within the ventral retina. In 2 completely mapped retinas, only 2 fibers from a total of 15,359 terminated in the dorsal retina. The major synapse made by each efferent fiber is with a single Efferent Target Amacrine Cell (TC). This synapse consists of 5-25 boutons of 2μm diameter, each with multiple active zones, pressed into the TC soma or synapsing with a basketwork of rudimentary TC dendrites in the inner nuclear layer (INL). This basketwork, which is sheathed by Muller cells processes, defines a private neuropil in the INL within which TCs were also seen to receive input from retinal neurons. In addition to the major synapse, efferent fibers typically produce several very thin processes that terminate nearby in single small boutons and for which the soma of a local amacrine cell is one of the likely postsynaptic partners. A minority of efferent fibers also give rise to a thicker process terminating in a strongly diaphorase positive ball about 5μm in diameter. PMID:19439107
Satellite switched FDMA advanced communication technology satellite program
NASA Technical Reports Server (NTRS)
Atwood, S.; Higton, G. H.; Wood, K.; Kline, A.; Furiga, A.; Rausch, M.; Jan, Y.
1982-01-01
The satellite switched frequency division multiple access system provided a detailed system architecture that supports a point to point communication system for long haul voice, video and data traffic between small Earth terminals at Ka band frequencies at 30/20 GHz. A detailed system design is presented for the space segment, small terminal/trunking segment at network control segment for domestic traffic model A or B, each totaling 3.8 Gb/s of small terminal traffic and 6.2 Gb/s trunk traffic. The small terminal traffic (3.8 Gb/s) is emphasized, for the satellite router portion of the system design, which is a composite of thousands of Earth stations with digital traffic ranging from a single 32 Kb/s CVSD voice channel to thousands of channels containing voice, video and data with a data rate as high as 33 Mb/s. The system design concept presented, effectively optimizes a unique frequency and channelization plan for both traffic models A and B with minimum reorganization of the satellite payload transponder subsystem hardware design. The unique zoning concept allows multiple beam antennas while maximizing multiple carrier frequency reuse. Detailed hardware design estimates for an FDMA router (part of the satellite transponder subsystem) indicate a weight and dc power budget of 353 lbs, 195 watts for traffic model A and 498 lbs, 244 watts for traffic model B.
Traverso, José A; Micalella, Chiara; Martinez, Aude; Brown, Spencer C; Satiat-Jeunemaître, Béatrice; Meinnel, Thierry; Giglione, Carmela
2013-03-01
N-terminal fatty acylations (N-myristoylation [MYR] and S-palmitoylation [PAL]) are crucial modifications affecting 2 to 4% of eukaryotic proteins. The role of these modifications is to target proteins to membranes. Predictive tools have revealed unexpected targets of these acylations in Arabidopsis thaliana and other plants. However, little is known about how N-terminal lipidation governs membrane compartmentalization of proteins in plants. We show here that h-type thioredoxins (h-TRXs) cluster in four evolutionary subgroups displaying strictly conserved N-terminal modifications. It was predicted that one subgroup undergoes only MYR and another undergoes both MYR and PAL. We used plant TRXs as a model protein family to explore the effect of MYR alone or MYR and PAL in the same family of proteins. We used a high-throughput biochemical strategy to assess MYR of specific TRXs. Moreover, various TRX-green fluorescent protein fusions revealed that MYR localized protein to the endomembrane system and that partitioning between this membrane compartment and the cytosol correlated with the catalytic efficiency of the N-myristoyltransferase acting at the N terminus of the TRXs. Generalization of these results was obtained using several randomly selected Arabidopsis proteins displaying a MYR site only. Finally, we demonstrated that a palmitoylatable Cys residue flanking the MYR site is crucial to localize proteins to micropatching zones of the plasma membrane.
Traverso, José A.; Micalella, Chiara; Martinez, Aude; Brown, Spencer C.; Satiat-Jeunemaître, Béatrice; Meinnel, Thierry; Giglione, Carmela
2013-01-01
N-terminal fatty acylations (N-myristoylation [MYR] and S-palmitoylation [PAL]) are crucial modifications affecting 2 to 4% of eukaryotic proteins. The role of these modifications is to target proteins to membranes. Predictive tools have revealed unexpected targets of these acylations in Arabidopsis thaliana and other plants. However, little is known about how N-terminal lipidation governs membrane compartmentalization of proteins in plants. We show here that h-type thioredoxins (h-TRXs) cluster in four evolutionary subgroups displaying strictly conserved N-terminal modifications. It was predicted that one subgroup undergoes only MYR and another undergoes both MYR and PAL. We used plant TRXs as a model protein family to explore the effect of MYR alone or MYR and PAL in the same family of proteins. We used a high-throughput biochemical strategy to assess MYR of specific TRXs. Moreover, various TRX–green fluorescent protein fusions revealed that MYR localized protein to the endomembrane system and that partitioning between this membrane compartment and the cytosol correlated with the catalytic efficiency of the N-myristoyltransferase acting at the N terminus of the TRXs. Generalization of these results was obtained using several randomly selected Arabidopsis proteins displaying a MYR site only. Finally, we demonstrated that a palmitoylatable Cys residue flanking the MYR site is crucial to localize proteins to micropatching zones of the plasma membrane. PMID:23543785
Ramírez-Franco, Jorge; Bartolomé-Martín, David; Alonso, Beatris; Torres, Magdalena; Sánchez-Prieto, José
2014-01-01
Cannabinoid receptors are the most abundant G protein-coupled receptors in the brain and they mediate retrograde short-term inhibition of neurotransmitter release, as well as long-term depression of synaptic transmission at many excitatory synapses. The induction of presynaptically silent synapses is a means of modulating synaptic strength, which is important for synaptic plasticity. Persistent activation of cannabinoid type 1 receptors (CB1Rs) mutes GABAergic terminals, although it is unclear if CB1Rs can also induce silencing at glutamatergic synapses. Cerebellar granule cells were transfected with VGLUT1-pHluorin to visualise the exo-endocytotic cycle. We found that prolonged stimulation (10 min) of cannabinoid receptors with the agonist HU-210 induces the silencing of previously active synapses. However, the presynaptic silencing induced by HU-210 is transient as it reverses after 20 min. cAMP with forskolin prevented CB1R-induced synaptic silencing, via activation of the Exchange Protein directly Activated by cAMP (Epac). Furthermore, Epac activation accelerated awakening of already silent boutons. Electron microscopy revealed that silencing was associated with synaptic vesicle (SV) redistribution within the nerve terminal, which diminished the number of vesicles close to the active zone of the plasma membrane. Finally, by combining functional and immunocytochemical approaches, we observed a strong correlation between the release capacity of the nerve terminals and RIM1α protein content, but not that of Munc13-1 protein. These results suggest that prolonged stimulation of cannabinoid receptors can transiently silence glutamatergic nerve terminals. PMID:24533119
NASA Astrophysics Data System (ADS)
Diz, Paula; Hernández-Almeida, Iván; Bernárdez, Patricia; Pérez-Arlucea, Marta; Hall, Ian R.
2018-07-01
The modern Eastern Equatorial Pacific (EEP) is a key oceanographic region for regulating the Earth's climate system, accounting for between 5-10% of global marine production whilst also representing a major source of carbon dioxide efflux to the atmosphere. Changes in ocean dynamics linked to the nutrient supply from the Southern Ocean have been suggested to have played a dominant role in regulating EEP productivity over glacial-interglacial timescales of the past 500 ka. Yet, the full extent of the climate and oceanic teleconnections and the mechanisms promoting the observed increase of productivity occurring at glacial terminations remain poorly understood. Here we present multi-proxy, micropaleontological, geochemical and sedimentological records from the easternmost EEP to infer changes in atmospheric patterns and oceanic processes potentially influencing regional primary productivity over glacial-interglacial cycles of the mid-late Pleistocene (∼0-650 ka). These proxy data support a leading role for the north-south migration of the Intertropical Convergence Zone (ITCZ) in shaping past productivity variability in the EEP. Productivity increases during glacial periods and notably peaks at major and "extra" glacial terminations (those occurring 1-2 precession cycles after some major terminations) coincident with the inferred southernmost position of the ITCZ. The comparison of our reconstructions with proxy records of climate variability suggests the intensification of related extratropical atmospheric and oceanic teleconnections during deglaciation events. These processes may have re-activated the supply of southern sourced nutrients to the EEP, potentially contributing to enhanced productivity in the EEP and thus counterbalancing the oceanic carbon dioxide outgassing at glacial terminations.
Rosenbaum, Jason N; Duggan, Anne; García-Añoveros, Jaime
2011-02-01
Insm1 is a zinc-finger transcription factor transiently expressed throughout the developing nervous system in late progenitors and nascent neurons. Insm1 is also highly expressed in medulloblastomas and other neuroendocrine tumors. We generated mice lacking the Insm1 gene and used them to elucidate its role in neurogenic proliferation of the embryonic olfactory epithelium. We found that deletion of Insm1 results in more apical cells and fewer nascent and mature neurons. In the embryonic olfactory epithelium of Insm1 mutants we detect fewer basal progenitors, which produce neurons, and more apical progenitors, which at this stage produce additional progenitors. Furthermore, in the mutants we detect fewer progenitors expressing NEUROD1, a marker of terminally dividing, neuronogenic (neuron-producing) progenitors (immediate neuronal precursors), and more progenitors expressing ASCL1, a marker of the transit amplifying progenitors that migrate from the apical to the basal edges of the epithelium while dividing to generate the terminal, neuronogenic progenitors. Finally, with timed administration of nucleoside analogs we demonstrate that the Insm1 mutants contain fewer terminally dividing progenitors at embryonic day 12.5. Altogether, these results suggest a role for Insm1 in promoting the transition of progenitors from apical and proliferative to basal, terminal and neuronogenic. This role appears partially conserved with that of its nematode ortholog, egl-46. The similar effects of Insm1 deletion on progenitors of embryonic olfactory epithelium and cortex point to striking parallels in the development of these neuroepithelia, and particularly between the basal progenitors of olfactory epithelium and the subventricular zone progenitors of cortex.
Mechanism-specific effects of adenosine on ventricular tachycardia.
Lerman, Bruce B; Ip, James E; Shah, Bindi K; Thomas, George; Liu, Christopher F; Ciaccio, Edward J; Wit, Andrew L; Cheung, Jim W; Markowitz, Steven M
2014-12-01
There is no universally accepted method by which to diagnose clinical ventricular tachycardia (VT) due to cAMP-mediated triggered activity. Based on cellular and clinical data, adenosine termination of VT is thought to be consistent with a diagnosis of triggered activity. However, a major gap in evidence mitigates the validity of this proposal, namely, defining the specificity of adenosine response in well-delineated reentrant VT circuits. To this end, we systematically studied the effects of adenosine in a model of canine reentrant VT and in human reentrant VT, confirmed by 3-dimensional, pace- and substrate mapping. Adenosine (12 mg [IQR 12-24]) failed to terminate VT in 31 of 31 patients with reentrant VT due to structural heart disease, and had no effect on VT cycle length (age, 67 years [IQR 53-74]); ejection fraction, 35% [IQR 20-55]). In contrast, adenosine terminated VT in 45 of 50 (90%) patients with sustained focal right or left outflow tract tachycardia. The sensitivity of adenosine for identifying VT due to triggered activity was 90% (95% CI, 0.78-0.97) and its specificity was 100% (95% CI, 0.89-1.0). Additionally, reentrant circuits were mapped in the epicardial border zone of 4-day-old infarcts in mongrel dogs. Adenosine (300-400 μg/kg) did not terminate sustained VT or have any effect on VT cycle length. These data support the concept that adenosine's effects on ventricular myocardium are mechanism specific, such that termination of VT in response to adenosine is diagnostic of cAMP-mediated triggered activity. © 2014 Wiley Periodicals, Inc.
A viscoplastic shear-zone model for episodic slow slip events in oceanic subduction zones
NASA Astrophysics Data System (ADS)
Yin, A.; Meng, L.
2016-12-01
Episodic slow slip events occur widely along oceanic subduction zones at the brittle-ductile transition depths ( 20-50 km). Although efforts have been devoted to unravel their mechanical origins, it remains unclear about the physical controls on the wide range of their recurrence intervals and slip durations. In this study we present a simple mechanical model that attempts to account for the observed temporal evolution of slow slip events. In our model we assume that slow slip events occur in a viscoplastic shear zone (i.e., Bingham material), which has an upper static and a lower dynamic plastic yield strength. We further assume that the hanging wall deformation is approximated as an elastic spring. We envision the shear zone to be initially locked during forward/landward motion but is subsequently unlocked when the elastic and gravity-induced stress exceeds the static yield strength of the shear zone. This leads to backward/trenchward motion damped by viscous shear-zone deformation. As the elastic spring progressively loosens, the hanging wall velocity evolves with time and the viscous shear stress eventually reaches the dynamic yield strength. This is followed by the termination of the trenchward motion when the elastic stress is balanced by the dynamic yield strength of the shear zone and the gravity. In order to account for the zig-saw slip-history pattern of typical repeated slow slip events, we assume that the shear zone progressively strengthens after each slow slip cycle, possibly caused by dilatancy as commonly assumed or by progressive fault healing through solution-transport mechanisms. We quantify our conceptual model by obtaining simple analytical solutions. Our model results suggest that the duration of the landward motion increases with the down-dip length and the static yield strength of the shear zone, but decreases with the ambient loading velocity and the elastic modulus of the hanging wall. The duration of the backward/trenchward motion depends on the thickness, viscosity, and dynamic yield strength of the shear zone. Our model predicts a linear increase in slip with time during the landward motion and an exponential decrease in slip magnitude during the trenchward motion.
Multiple parietal-frontal pathways mediate grasping in macaque monkeys
Gharbawie, Omar A.; Stepniewska, Iwona; Qi, Huixin; Kaas, Jon H.
2011-01-01
The nodes of a parietal-frontal pathway that mediates grasping in primates are in anterior intraparietal area (AIP) and ventral premotor cortex (PMv). Nevertheless, multiple somatosensory and motor representations of the hand, respectively in parietal and frontal cortex, suggest that additional pathways remain unrealized. We explored this possibility in macaque monkeys by injecting retrograde tracers into grasp zones identified in M1, PMv, and area 2 with long train electrical stimulation. The M1 grasp zone was densely connected with other frontal cortex motor regions. The remainder of the connections originated from somatosensory areas 3a and S2/PV, and from the medial bank and fundus of the intraparietal sulcus (IPS). The PMv grasp zone was also densely connected with frontal cortex motor regions, albeit to a lesser extent than the M1 grasp zone. The remainder of the connections originated from areas S2/PV and aspects of the inferior parietal lobe such as PF, PFG, AIP, and the tip of the IPS. The area 2 grasp zone was densely connected with the hand representations of somatosensory areas 3b, 1, and S2/PV. The remainder of the connections was with areas 3a and 5 and the medial bank and fundus of the IPS. Connections with frontal cortex were relatively weak and concentrated in caudal M1. Thus, the three grasp zones may be nodes of parallel parietal-frontal pathways. Differential points of origin and termination of each pathway suggest varying functional specializations. Direct and indirect connections between those parietal-frontal pathways likely coordinate their respective functions into an accurate grasp. PMID:21832196
Relative air temperature analysis external building on Gowa Campus
NASA Astrophysics Data System (ADS)
Mustamin, Tayeb; Rahim, Ramli; Baharuddin; Jamala, Nurul; Kusno, Asniawaty
2018-03-01
This study aims to data analyze the relative temperature and humidity of the air outside the building. Data retrieval taken from weather monitoring device (monitoring) Vaisala, RTU (Remote Terminal Unit), Which is part of the AWS (Automatic Weather Stations) Then Processing data processed and analyzed by using Microsoft Excel program in the form of graph / picture fluctuation Which shows the average value, standard deviation, maximum value, and minimum value. Results of data processing then grouped in the form: Daily, and monthly, based on time intervals every 30 minutes. The results showed Outside air temperatures in March, April, May and September 2016 Which entered in the thermal comfort zone according to SNI standard (Indonesian National Standard) only at 06.00-10.00. In late March to early April Thermal comfort zone also occurs at 15.30-18.00. The highest maximum air temperature occurred in September 2016 at 11.01-11.30 And the lowest minimum value in September 2016, time 6:00 to 6:30. The result of the next analysis shows the level of data conformity with thermal comfort zone based on SNI (Indonesian National Standard) every month.
Identification and interpretation of tectonic features from Skylab imagery. [California to Arizona
NASA Technical Reports Server (NTRS)
Abdel-Gawad, M. (Principal Investigator)
1974-01-01
The author has identified the following significant results. S190-B imagery confirmed previous conclusions from S190-A that the Garlock fault does not extend eastward beyond its known termination near the southern end of Death Valley. In the Avawatz Mountains, California, two faults related to the Garlock fault zone (Mule Spring fault and Leach Spring fault) show evidence of recent activity. There is evidence that faulting related to Death Valley fault zone extends southeastward across the Old Dad Mountains. There, the Old Dad fault shows evidence of recent activity. A significant fault lineament has been identified from McCullough Range, California southeastward to Eagle Tail Mountains in southwestern Arizona. The lineament appears to control tertiary and possible cretaceous intrusives. Considerable right lateral shear is suspected to have taken place along parts of this lineament.
Microstructure of the combustion zone: Thin-binder AP-polymer sandwiches
NASA Technical Reports Server (NTRS)
Price, E. W.; Panyam, R. R.; Sigman, R. K.
1980-01-01
Experimental results are summarized for systematic quench-burning tests on ammonium perchlorate-HC binder sandwiches with binder thicknesses in the range 10 - 150 microns. Tests included three binders (polysulfide, polybutadiene-acrylonitrile, and hydroxy terminated polybutadiene), and pressures from 1.4 to 14 MPa. In addition, deflagration limits were determined in terms of binder thickness and pressure. Results are discussed in terms of a qualitative theory of sandwich burning consolidated from various sources. Some aspects of the observed results are explained only speculatively.
SEISMICITY OF THE LASSEN PEAK AREA, CALIFORNIA: 1981-1983.
Walter, Stephen R.; Rojas, Vernonica; Kollmann, Auriel
1984-01-01
Over 700 earthquakes occurred in the vicinity of Lassen Peak, California, from February 1981 through December 1983. These earthquakes define a broad, northwest-trending seismic zone that extends from the Sierra Nevada through the Lassen Peak area and either terminates or is offset to the northeast about 20 kilometers northwest of Lassen Peak. Approximately 25% of these earthquakes are associated with the geothermal system south of Lassen Peak. Earthquakes in the geothermal area generally occur at depths shallower than 6 kilometers.
The Nova-Canton Trough and the Late Cretaceous evolution of the central Pacific
NASA Astrophysics Data System (ADS)
Joseph, Devorah; Taylor, Brain; Shor, Alexander N.; Yamazaki, Toshitsugu
Free-air gravity anomalies derived from satellite altimetry data show that the major Pacific fracture zones, from the Pau to Marquesas, are co-polar about an Euler pole located at 150.5°W, 34.6°S for the period preceding chron 33 and including a large portion of the Cretaceous Normal Superchron. They also show continuity of the Clipperton Fracture Zone through the Line Islands to the Nova-Canton ridge and trough; this Canton-Clipperton trend is co-polar to the same pole. Sidescan-sonar and bathymetry data in the Nova-Canton Trough region reveal N140°E-striking abyssal hill topography south of the N70°E-striking structures of the Nova-Canton Trough and crustal fabric striking normal to the trough (N160°E) to the north. We conclude that the Nova-Canton Trough is the Middle Cretaceous extension of the Clipperton Fracture Zone. We propose that the anomalous depths (7000-8400 m) of the trough between 167°30'-168°30'W are the result of a complex plate reorganization. Conjugate magnetic anomaly lineations M1-M3 in the Phoenix lineations between the Central Pacific Fracture Zone and the Phoenix Fracture Zone and the absence of lineations younger than anomaly M3 west of the Phoenix Fracture Zone suggest that spreading may have gradually ceased along the Pacific-Phoenix system from west to east. We infer that the remaining active segment of the Pacific-Phoenix spreading system after anomaly M1 time was the easternmost section of the Phoenix lineations. At ˜M0 time, the Pacific-Phoenix spreading axis stretched from lineated bathymetric depressions lying between 180°W and the Phoenix Islands to ˜168°W and included the western deep of the Nova-Canton Trough. We hypothesize that accretion terminated on the Pacific-Phoenix spreading axis shortly after M0 time and that the absence of an M0 isochron in the region between the eastern Phoenix lineations and the Nova-Canton Trough, or along the Nova-Canton Trough itself, may be due to a decrease in spreading rate prior to termination. We concur with previous hypotheses that portions of the Phoenix plate were trapped on the Pacific plate by a ridge jump south to the nascent Manihiki Plateau; some portions were overprinted by the Aptian volcanism that formed the Manihiki Plateau and Robbie Ridge. Pacific-Farallon spreading south of the Nova-Canton Trough jumped westwards, initiating transcurrent motion along the easternmost section of the failed ˜M0 spreading axis (the western deep of the Nova-Canton Trough) which subsequently became the western end of the Clipperton (Pacific-Farallon) transform. In our reconstruction, the northeast and southeast margins of the Manihiki Plateau are rifted margins that form the western limit of Pacific-Farallon spreading between the Clipperton, Galapagos, and Marquesas fracture zones.
Alagappan, Valliappan; Hefferan, Albert; Parivallal, Aarthi
2018-04-01
Right to access in the built environment creates equal and nondiscriminatory opportunities to a person with disabilities in order to move freely around and interact positively without hindrance and barriers. The objective of the study is to understand the existing accessibility related issues and implementation of guidelines and standards for public buildings. The technical verification using onsite and offsite access audit format for current provision of facilities in the internal and external environment has been carried out with the format prepared in reference to Central Public Works Department (CPWD) accessibility guidelines for mobility impaired and elderly and American Disability Act (ADA) guidelines. The access audit format included parameters like accessibility, safety, security, comfort and convenience and it addresses the barriers faced by wheel chair users, people with crutches, prosthetics and with non-assistive devices. The study addressed accessibility compliance in three zones of the building with initiation from parking area zone, inside the building, and area outside the building premises. The findings highlight the environmental barriers encountered by mobility impaired people and represented graphically in the layout plan and physical effort required to overcome the challenges in the built environment. The overall accessibility compliance is 42% in the interstate bus terminal. Implications for rehabilitation The study identifies the environmental limitations, human and technologically facilitators with the help of Central Public Works Department (CPWD) and American Disability Act (ADA) guidelines (1990). It highlights barriers for mobility-impaired users, by demonstrating in a spatial layout and the means to facilitate easy access with minimal frustration, stress and with less physical effort. It demonstrates the need for preparation of separate guidelines for making the existing types of buildings to be access and disabled-friendly. New accessibility guidelines shall be prepared by incorporating concepts like such as relative accessibility into new bus terminal buildings. Guidelines help the disabled in the process of rehabilitation and develop inclusiveness not rather than alienation.
NASA Astrophysics Data System (ADS)
Bocin, A.; Stephenson, R.; Matenco, L.; Mocanu, V.
2013-11-01
A 2D gravity and magnetic data model has been constructed along a 71 km densely observed profile, called DACIA PLAN GRAV MAN's. The profile crosses part of the nappe pile of the south-eastern Carpathians and includes the seismically active Vrancea Zone and was acquired with the objective to illuminate the basement structure and affinity in this area. The modelling approach was to create an initial model from well constrained geological information, integrate it with previous seismic ray tracing and tomographic models and then alter it outside the a priori constraints in order to reach the best fit between observed and calculated potential field anomalies. The results support a realignment of the position of the TTZ (Tornquist-Teisseyre Zone), the profound tectonic boundary within Europe that separates Precambrian cratonic lithosphere of the East European Craton (EEC) from younger accreted lithosphere of Phanerozoic mobile belts to its west. The TTZ is shown to lie further to the south-west than was previously inferred within Romania, where it is largely obscured by the Carpathian nappes. The crust of the EEC beneath the south-eastern Carpathians is inferred to terminate along a major crustal structure lying just west of the Vrancea seismogenic zone. The intermediate depth seismicity of the Vrancea Zone therefore lies within the EEC lithosphere, generally supporting previously proposed models invoking delamination of cratonic lithosphere as the responsible mechanism.
Cdx mutant axial progenitor cells are rescued by grafting to a wild type environment.
Bialecka, Monika; Wilson, Valerie; Deschamps, Jacqueline
2010-11-01
Cdx transcription factors are required for axial extension. Cdx genes are expressed in the posterior growth zone, a region that supplies new cells for axial elongation. Cdx2(+/-)Cdx4(-/-) (Cdx2/4) mutant embryos show abnormalities in axis elongation from E8.5, culminating in axial truncation at E10.5. These data raised the possibility that the long-term axial progenitors of Cdx mutants are intrinsically impaired in their ability to contribute to posterior growth. We investigated whether we could identify cell-autonomous defects of the axial progenitor cells by grafting mutant cells into a wild type growth zone environment. We compared the contribution of GFP labeled mutant and wild type progenitors grafted to unlabeled wild type recipients subsequently cultured over the period during which Cdx2/4 defects emerge. Descendants of grafted cells were scored for their contribution to differentiated tissues in the elongating axis and to the posterior growth zone. No difference between the contribution of descendants from wild type and mutant grafted progenitors was detected, indicating that rescue of the Cdx mutant progenitors by the wild type recipient growth zone is provided non-cell autonomously. Recently, we showed that premature axial termination of Cdx mutants can be partly rescued by stimulating canonical Wnt signaling in the posterior growth zone. Taken together with the data shown here, this suggests that Cdx genes function to maintain a signaling-dependent niche for the posterior axial progenitors. Copyright © 2010 Elsevier Inc. All rights reserved.
NASA Astrophysics Data System (ADS)
Koehl, Jean-Baptiste P.; Bergh, Steffen G.; Henningsen, Tormod; Faleide, Jan Inge
2018-03-01
The SW Barents Sea margin experienced a pulse of extensional deformation in the Middle-Late Devonian through the Carboniferous, after the Caledonian Orogeny terminated. These events marked the initial stages of formation of major offshore basins such as the Hammerfest and Nordkapp basins. We mapped and analyzed three major fault complexes, (i) the Måsøy Fault Complex, (ii) the Rolvsøya fault, and (iii) the Troms-Finnmark Fault Complex. We discuss the formation of the Måsøy Fault Complex as a possible extensional splay of an overall NE-SW-trending, NW-dipping, basement-seated Caledonian shear zone, the Sørøya-Ingøya shear zone, which was partly inverted during the collapse of the Caledonides and accommodated top-NW normal displacement in Middle to Late Devonian-Carboniferous times. The Troms-Finnmark Fault Complex displays a zigzag-shaped pattern of NNE-SSW- and ENE-WSW-trending extensional faults before it terminates to the north as a WNW-ESE-trending, NE-dipping normal fault that separates the southwesternmost Nordkapp basin in the northeast from the western Finnmark Platform and the Gjesvær Low in the southwest. The WNW-ESE-trending, margin-oblique segment of the Troms-Finnmark Fault Complex is considered to represent the offshore prolongation of a major Neoproterozoic fault complex, the Trollfjorden-Komagelva Fault Zone, which is made of WNW-ESE-trending, subvertical faults that crop out on the island of Magerøya in NW Finnmark. Our results suggest that the Trollfjorden-Komagelva Fault Zone dies out to the northwest before reaching the western Finnmark Platform. We propose an alternative model for the origin of the WNW-ESE-trending segment of the Troms-Finnmark Fault Complex as a possible hard-linked, accommodation cross fault that developed along the Sørøy-Ingøya shear zone. This brittle fault decoupled the western Finnmark Platform from the southwesternmost Nordkapp basin and merged with the Måsøy Fault Complex in Carboniferous times. Seismic data over the Gjesvær Low and southwesternmost Nordkapp basin show that the low-gravity anomaly observed in these areas may result from the presence of Middle to Upper Devonian sedimentary units resembling those in Middle Devonian, spoon-shaped, late- to post-orogenic collapse basins in western and mid-Norway. We propose a model for the formation of the southwesternmost Nordkapp basin and its counterpart Devonian basin in the Gjesvær Low by exhumation of narrow, ENE-WSW- to NE-SW-trending basement ridges along a bowed portion of the Sørøya-Ingøya shear zone in the Middle to Late Devonian-early Carboniferous. Exhumation may have involved part of a large-scale metamorphic core complex that potentially included the Lofoten Ridge, the West Troms Basement Complex and the Norsel High. Finally, we argue that the Sørøya-Ingøya shear zone truncated and decapitated the Trollfjorden-Komagelva Fault Zone during the Caledonian Orogeny and that the western continuation of the Trollfjorden-Komagelva Fault Zone was mostly eroded and potentially partly preserved in basement highs in the SW Barents Sea.
Deutzmann, R; Fowler, S; Zhang, X; Boone, K; Dexter, S; Boot-Handford, R P; Rachel, R; Sarras, M P
2000-11-01
The body wall of hydra (a member of the phylum Cnidaria) is structurally reduced to an epithelial bilayer with an intervening extracellular matrix (ECM). Previous studies have established that cell-ECM interactions are important for morphogenesis and cell differentiation in this simple metazoan. The ECM of hydra is particularly interesting because it represents a primordial form of matrix. Despite progress in our understanding of hydra ECM, we still know little about the nature of hydra collagens. In the current study we provide a molecular, biochemical and functional analysis of a hydra fibrillar collagen that has similarity to vertebrate type I and type II collagens. This fibrillar collagen has been named hydra collagen-I (Hcol-I) because of its structure and because it is the first ECM collagen to be identified in hydra. It represents a novel member of the collagen family. Similar to vertebrate type I and II collagens, Hcol-I contains an N-terminal propeptide-like domain, a triple helical domain containing typical Gly-X-Y repeats and a C-terminal propeptide domain. The overall identity to vertebrate fibrillar collagens is about 30%, while the identity of the C-terminal propeptide domain is 50%. Because the N-terminal propeptide domain is retained after post-translational processing, Hcol-I does not form thick fibers as seen in vertebrates. This was confirmed using transmission electron microscopy to study rotary shadow images of purified Hcol-I. In addition, absence of crucial lysine residues and an overall reduction in proline content, results in reduced crosslinking of fibrils and increased flexibility of the molecule, respectively. These structural changes in Hcol-I help to explain the flexible properties of hydra ECM. Immunocytochemical studies indicate that Hcol-I forms the 10 nm fibrils that comprise the majority of molecules in the central fibrous zone of hydra ECM. The central fibrous zone resides between the two subepithelial zones where hydra laminin is localized. While previous studies have shown that basal lamina components like laminin are expressed by the endoderm, in situ hybridisation studies show that Hcol-I mRNA expression is restricted to the ectoderm. Hcol-I expression is upregulated during head regeneration, and antisense studies using thio-oligonucleotides demonstrated that blocking the translation of Hcol-I leads to a reversible inhibition of head morphogenesis during this regenerative process. Taken in total, the data presented in this study indicate that Hcol-I is required for morphogensis in hydra and represents a novel fibrillar collagen whose structural characteristics help to explain the unique biophysical properties of hydra ECM. Interestingly, the structure of Hcol-I mimics what is seen in Ehlers-Danlos syndrome type VII in humans; an inherited pathological condition that leads to joint and skin abnormalities. Hcol-I therefore illustrates an adaptive trait in which the normal physiological situation in hydra translates into a pathological condition in humans.
Proliferation zones in the axolotl brain and regeneration of the telencephalon
2013-01-01
Background Although the brains of lower vertebrates are known to exhibit somewhat limited regeneration after incisional or stab wounds, the Urodele brain exhibits extensive regeneration after massive tissue removal. Discovering whether and how neural progenitor cells that reside in the ventricular zones of Urodeles proliferate to mediate tissue repair in response to injury may produce novel leads for regenerative strategies. Here we show that endogenous neural progenitor cells resident to the ventricular zone of Urodeles spontaneously proliferate, producing progeny that migrate throughout the telencephalon before terminally differentiating into neurons. These progenitor cells appear to be responsible for telencephalon regeneration after tissue removal and their activity may be up-regulated by injury through an olfactory cue. Results There is extensive proliferation of endogenous neural progenitor cells throughout the ventricular zone of the adult axolotl brain. The highest levels are observed in the telencephalon, especially the dorsolateral aspect, and cerebellum. Lower levels are observed in the mesencephalon and rhombencephalon. New cells produced in the ventricular zone migrate laterally, dorsally and ventrally into the surrounding neuronal layer. After migrating from the ventricular zone, the new cells primarily express markers of neuronal differentiative fates. Large-scale telencephalic tissue removal stimulates progenitor cell proliferation in the ventricular zone of the damaged region, followed by proliferation in the tissue that surrounds the healing edges of the wound until the telencephalon has completed regeneration. The proliferative stimulus appears to reside in the olfactory system, because telencephalic regeneration does not occur in the brains of olfactory bulbectomized animals in which the damaged neural tissue simply heals over. Conclusion There is a continual generation of neuronal cells from neural progenitor cells located within the ventricular zone of the axolotl brain. Variable rates of proliferation were detected across brain regions. These neural progenitor cells appear to mediate telencephalic tissue regeneration through an injury-induced olfactory cue. Identification of this cue is our future goal. PMID:23327114
Proliferation zones in the axolotl brain and regeneration of the telencephalon.
Maden, Malcolm; Manwell, Laurie A; Ormerod, Brandi K
2013-01-17
Although the brains of lower vertebrates are known to exhibit somewhat limited regeneration after incisional or stab wounds, the Urodele brain exhibits extensive regeneration after massive tissue removal. Discovering whether and how neural progenitor cells that reside in the ventricular zones of Urodeles proliferate to mediate tissue repair in response to injury may produce novel leads for regenerative strategies. Here we show that endogenous neural progenitor cells resident to the ventricular zone of Urodeles spontaneously proliferate, producing progeny that migrate throughout the telencephalon before terminally differentiating into neurons. These progenitor cells appear to be responsible for telencephalon regeneration after tissue removal and their activity may be up-regulated by injury through an olfactory cue. There is extensive proliferation of endogenous neural progenitor cells throughout the ventricular zone of the adult axolotl brain. The highest levels are observed in the telencephalon, especially the dorsolateral aspect, and cerebellum. Lower levels are observed in the mesencephalon and rhombencephalon. New cells produced in the ventricular zone migrate laterally, dorsally and ventrally into the surrounding neuronal layer. After migrating from the ventricular zone, the new cells primarily express markers of neuronal differentiative fates. Large-scale telencephalic tissue removal stimulates progenitor cell proliferation in the ventricular zone of the damaged region, followed by proliferation in the tissue that surrounds the healing edges of the wound until the telencephalon has completed regeneration. The proliferative stimulus appears to reside in the olfactory system, because telencephalic regeneration does not occur in the brains of olfactory bulbectomized animals in which the damaged neural tissue simply heals over. There is a continual generation of neuronal cells from neural progenitor cells located within the ventricular zone of the axolotl brain. Variable rates of proliferation were detected across brain regions. These neural progenitor cells appear to mediate telencephalic tissue regeneration through an injury-induced olfactory cue. Identification of this cue is our future goal.
NASA Astrophysics Data System (ADS)
Jonk, R.; Biermann, C.
2002-05-01
Detailed structural analyses are presented of the Neogene Sorbas Basin adjacent to the E-W striking Gafarillos fault zone and the Vera Basin adjacent to the 020° striking Palomares fault zone in southeastern Spain. A stress regime with an E-W oriented subhorizontal maximum principal stress ( σ1) existed in pre-Tortonian (>11.3 Ma) time. A strike-slip regime with NW-SE oriented compression during Tortonian and earliest Messinian time caused dextral displacement along the E-W trending Gafarillos fault of approximately 10 km. Structural analysis indicates that most displacement took place in the Early Tortonian. Deformational patterns within the adjacent pull-apart basin reflect a dextral simple shear-zone of at least 500 m width. Kinematical analysis of folds in the Sorbas Basin suggests, however, that rotational effects are largely caused by rigid-body rotation without much internal deformation. Sinistral strike-slip displacements occurred along the Palomares fault zone under the influence of the same stress-regime. An abrupt change in the orientation of the stress field to N-S directed compression in earliest Messinian time (6.5 Ma) caused the termination of displacements along the Gafarillos fault zone, whereas the 020° trending Palomares fault zone continued to accumulate sinistral strike-slip displacements of about 25 km. Volcanism occurred along splays of the fault zone. A wider shear-zone of a few kilometers width evolved, in which considerable anti-clockwise rotation of folds occurred. Kinematic analysis of these folds shows that these rotational effects are again dominantly rigid-body rotations. Assuming rotations are merely caused by simple-shear deformation overestimates the amounts of strain. A better way to deal with simple-shear deformation is to compare observed shortening caused by folding with the magnitude of rotation of fold-hinges.
NASA Astrophysics Data System (ADS)
Mancilla, Flor de Lis; Heit, Benjamin; Morales, Jose; Yuan, Xiaohui; Stich, Daniel; Molina-Aguilera, Antonio; Azañon, Jose Miguel; Martín, Rosa
2018-03-01
We study the crustal and lithospheric mantle structure under central Betics in the westernmost Mediterranean region by migrating P-receiver functions along a dense seismic profile (∼2 km interstation distance). The profile, North-South oriented, probes the crustal structure of different geological units, from the Alboran domain in the south with metamorphic rocks, through the External Zones with sedimentary rocks to the Variscan terrains of the Iberian Massif in the north. From north to south, the Moho depth increases from ∼30 km to ∼46 km underneath the Guadix basin, due to the underthrusting of the Iberian crust below the Alboran crust, and suddenly shallows to ∼30 km underneath the Internal Zones with a step of 17 km. This sharp Moho step correlates well with a lithospheric step of ∼40 km, where the thickness of the lithosphere changes abruptly from ∼100 km in the north to ∼50 km in the south. We interpret this sharp and prominent lithospheric step as the termination of the Iberian lithosphere caused by a near-vertical STEP (Subduction-Transform-Edge-Propagator) fault that continues towards the surface as a positive flower tectonic structure of crustal scale. This STEP fault is located at the northern edge of the narrow Westernmost Mediterranean subduction system facilitating the slab rollback motion towards the west. The sharp termination of the Iberian lithosphere occurs under the contact between the Alpujarride and the Nevado-Filabride complexes of the Alboran domain in an ENE-WSW right-lateral transpressive shear zone. The thickest crust and lithosphere do not correlate with the highest topography along the profile suggesting that this high topography is a combined effect of the positive flower structure, and the push up of the asthenosphere produced by the removal of the Iberian lithosphere.
Evidence of a sensory processing unit in the mammalian macula
NASA Technical Reports Server (NTRS)
Chimento, T. C.; Ross, M. D.
1996-01-01
We cut serial sections through the medial part of the rat vestibular macula for transmission electron microscopic (TEM) examination, computer-assisted 3-D reconstruction, and compartmental modeling. The ultrastructural research showed that many primary vestibular neurons have an unmyelinated segment, often branched, that extends between the heminode (putative site of the spike initiation zone) and the expanded terminal(s) (calyx, calyces). These segments, termed the neuron branches, and the calyces frequently have spine-like processes of various dimensions with bouton endings that morphologically are afferent, efferent, or reciprocal to other macular neural elements. The major questions posed by this study were whether small details of morphology, such as the size and location of neuronal processes or synapses, could influence the output of a vestibular afferent, and whether a knowledge of morphological details could guide the selection of values for simulation parameters. The conclusions from our simulations are (1) values of 5.0 k omega cm2 for membrane resistivity and 1.0 nS for synaptic conductance yield simulations that best match published physiological results; (2) process morphology has little effect on orthodromic spread of depolarization from the head (bouton) to the spike initiation zone (SIZ); (3) process morphology has no effect on antidromic spread of depolarization to the process head; (4) synapses do not sum linearly; (5) synapses are electrically close to the SIZ; and (6) all whole-cell simulations should be run with an active SIZ.
Modeling occupancy distribution in large spaces with multi-feature classification algorithm
Wang, Wei; Chen, Jiayu; Hong, Tianzhen
2018-04-07
We present that occupancy information enables robust and flexible control of heating, ventilation, and air-conditioning (HVAC) systems in buildings. In large spaces, multiple HVAC terminals are typically installed to provide cooperative services for different thermal zones, and the occupancy information determines the cooperation among terminals. However, a person count at room-level does not adequately optimize HVAC system operation due to the movement of occupants within the room that creates uneven load distribution. Without accurate knowledge of the occupants’ spatial distribution, the uneven distribution of occupants often results in under-cooling/heating or over-cooling/heating in some thermal zones. Therefore, the lack of high-resolutionmore » occupancy distribution is often perceived as a bottleneck for future improvements to HVAC operation efficiency. To fill this gap, this study proposes a multi-feature k-Nearest-Neighbors (k-NN) classification algorithm to extract occupancy distribution through reliable, low-cost Bluetooth Low Energy (BLE) networks. An on-site experiment was conducted in a typical office of an institutional building to demonstrate the proposed methods, and the experiment outcomes of three case studies were examined to validate detection accuracy. One method based on City Block Distance (CBD) was used to measure the distance between detected occupancy distribution and ground truth and assess the results of occupancy distribution. Finally, the results show the accuracy when CBD = 1 is over 71.4% and the accuracy when CBD = 2 can reach up to 92.9%.« less
Modeling occupancy distribution in large spaces with multi-feature classification algorithm
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wang, Wei; Chen, Jiayu; Hong, Tianzhen
We present that occupancy information enables robust and flexible control of heating, ventilation, and air-conditioning (HVAC) systems in buildings. In large spaces, multiple HVAC terminals are typically installed to provide cooperative services for different thermal zones, and the occupancy information determines the cooperation among terminals. However, a person count at room-level does not adequately optimize HVAC system operation due to the movement of occupants within the room that creates uneven load distribution. Without accurate knowledge of the occupants’ spatial distribution, the uneven distribution of occupants often results in under-cooling/heating or over-cooling/heating in some thermal zones. Therefore, the lack of high-resolutionmore » occupancy distribution is often perceived as a bottleneck for future improvements to HVAC operation efficiency. To fill this gap, this study proposes a multi-feature k-Nearest-Neighbors (k-NN) classification algorithm to extract occupancy distribution through reliable, low-cost Bluetooth Low Energy (BLE) networks. An on-site experiment was conducted in a typical office of an institutional building to demonstrate the proposed methods, and the experiment outcomes of three case studies were examined to validate detection accuracy. One method based on City Block Distance (CBD) was used to measure the distance between detected occupancy distribution and ground truth and assess the results of occupancy distribution. Finally, the results show the accuracy when CBD = 1 is over 71.4% and the accuracy when CBD = 2 can reach up to 92.9%.« less
NASA Astrophysics Data System (ADS)
Wiryadinata, Steven
Service life modeling was performed to gage the viability of unitary 3.5 kWt, ground-source terminal heat pumps (GTHP) employing horizontal directionally drilled geothermal heat exchangers (GHX) over air-source terminal heat pumps (PTHP) in hotels and motels and residential apartment building sectors in California's coastal and inland climates. Results suggest the GTHP can reduce hourly peak demand for the utility by 7%-25% compared to PTHP, depending on the climate and building type. The annual energy savings, which range from -1% to 5%, are highly dependent on the GTHP pump energy use relative to the energy savings attributed to the difference in ground and air temperatures (DeltaT). In mild climates with small ?T, the pump energy use may overcome any advantage to utilizing a GHX. The majority of total levelized cost savings - ranging from 0.18/ft2 to 0.3/ft 2 - are due to reduced maintenance and lifetime capital cost normally associated with geothermal heat pump systems. Without these reductions (not validated for the GTHP system studied), the GTHP technology does not appear to offer significant advantages over PTHP in the climate zones studied here. The GTHP levelized cost was most sensitive to variations in installed cost and in some cases, energy use (influenced by climate zone choice), which together highlights the importance of climate selection for installation, and the need for larger market penetration of ground-source systems in order to bring down installed costs as the technology matures.
Tectonic and Structural Controls of Geothermal Activity in the Great Basin Region, Western USA
NASA Astrophysics Data System (ADS)
Faulds, J. E.; Hinz, N.; Kreemer, C. W.
2012-12-01
We are conducting a thorough inventory of structural settings of geothermal systems (>400 total) in the extensional to transtensional Great Basin region of the western USA. Most of the geothermal systems in this region are not related to upper crustal magmatism and thus regional tectonic and local structural controls are the most critical factors controlling the locations of the geothermal activity. A system of NW-striking dextral faults known as the Walker Lane accommodates ~20% of the North American-Pacific plate motion in the western Great Basin and is intimately linked to N- to NNE-striking normal fault systems throughout the region. Overall, geothermal systems are concentrated in areas with the highest strain rates within or proximal to the eastern and western margins of the Great Basin, with the high temperature systems clustering in transtensional areas of highest strain rate in the northwestern Great Basin. Enhanced extension in the northwestern Great Basin probably results from the northwestward termination of the Walker Lane and the concomitant transfer of dextral shear into west-northwest directed extension, thus producing a broad transtensional region. The capacity of geothermal power plants also correlates with strain rates, with the largest (hundreds of megawatts) along the Walker Lane or San Andreas fault system, where strain rates range from 10-100 nanostrain/yr to 1,000 nanostrain/yr, respectively. Lesser systems (tens of megawatts) reside in the Basin and Range (outside the Walker Lane), where local strain rates are typically < 10 nanostrain/yr. Of the 250+ geothermal fields catalogued, step-overs or relay ramps in normal fault zones serve as the most favorable setting, hosting ~32% of the systems. Such areas have multiple, overlapping fault strands, increased fracture density, and thus enhanced permeability. Other common settings include a) intersections between normal faults and strike-slip or oblique-slip faults (27%), where multiple minor faults connect major structures and fluids can flow readily through highly fractured, dilational quadrants, and b) normal fault terminations or tip-lines (22%), where horse-tailing generates closely-spaced faults and increased permeability. Other settings include accommodation zones (i.e., belts of intermeshing, oppositely dipping normal faults; 8%), major range-front faults (5-6%), and pull-aparts in strike-slip faults (4%). In addition, Quaternary faults lie within or near most systems. The relative scarcity of geothermal systems along displacement-maxima of major normal faults may be due to reduced permeability in thick zones of clay gouge and periodic release of stress in major earthquakes. Step-overs, terminations, intersections, and accommodation zones correspond to long-term, critically stressed areas, where fluid pathways are more likely to remain open in networks of closely-spaced, breccia-dominated fractures. These findings may help guide future exploration efforts, especially for blind geothermal systems, which probably comprise the bulk of the geothermal resources in the Great Basin.
A Cdk9-PP1 switch regulates the elongation-termination transition of RNA polymerase II.
Parua, Pabitra K; Booth, Gregory T; Sansó, Miriam; Benjamin, Bradley; Tanny, Jason C; Lis, John T; Fisher, Robert P
2018-06-13
The end of the RNA polymerase II (Pol II) transcription cycle is strictly regulated to prevent interference between neighbouring genes and to safeguard transcriptome integrity 1 . The accumulation of Pol II downstream of the cleavage and polyadenylation signal can facilitate the recruitment of factors involved in mRNA 3'-end formation and termination 2 , but how this sequence is initiated remains unclear. In a chemical-genetic screen, human protein phosphatase 1 (PP1) isoforms were identified as substrates of positive transcription elongation factor b (P-TEFb), also known as the cyclin-dependent kinase 9 (Cdk9)-cyclin T1 (CycT1) complex 3 . Here we show that Cdk9 and PP1 govern phosphorylation of the conserved elongation factor Spt5 in the fission yeast Schizosaccharomyces pombe. Cdk9 phosphorylates both Spt5 and a negative regulatory site on the PP1 isoform Dis2 4 . Sites targeted by Cdk9 in the Spt5 carboxy-terminal domain can be dephosphorylated by Dis2 in vitro, and dis2 mutations retard Spt5 dephosphorylation after inhibition of Cdk9 in vivo. Chromatin immunoprecipitation and sequencing analysis indicates that Spt5 is dephosphorylated as transcription complexes traverse the cleavage and polyadenylation signal, concomitant with the accumulation of Pol II phosphorylated at residue Ser2 of the carboxy-terminal domain consensus heptad repeat 5 . A conditionally lethal Dis2-inactivating mutation attenuates the drop in Spt5 phosphorylation on chromatin, promotes transcription beyond the normal termination zone (as detected by precision run-on transcription and sequencing 6 ) and is genetically suppressed by the ablation of Cdk9 target sites in Spt5. These results suggest that the transition of Pol II from elongation to termination coincides with a Dis2-dependent reversal of Cdk9 signalling-a switch that is analogous to a Cdk1-PP1 circuit that controls mitotic progression 4 .
Isolation of Synaptosomes, Synaptic Plasma Membranes, and Synaptic Junctional Complexes.
Michaelis, Mary L; Jiang, Lei; Michaelis, Elias K
2017-01-01
Isolation of synaptic nerve terminals or synaptosomes provides an opportunity to study the process of neurotransmission at many levels and with a variety of approaches. For example, structural features of the synaptic terminals and the organelles within them, such as synaptic vesicles and mitochondria, have been elucidated with electron microscopy. The postsynaptic membranes are joined to the presynaptic "active zone" of transmitter release through cell adhesion molecules and remain attached throughout the isolation of synaptosomes. These "post synaptic densities" or "PSDs" contain the receptors for the transmitters released from the nerve terminals and can easily be seen with electron microscopy. Biochemical and cell biological studies with synaptosomes have revealed which proteins and lipids are most actively involved in synaptic release of neurotransmitters. The functional properties of the nerve terminals, such as responses to depolarization and the uptake or release of signaling molecules, have also been characterized through the use of fluorescent dyes, tagged transmitters, and transporter substrates. In addition, isolated synaptosomes can serve as the starting material for the isolation of relatively pure synaptic plasma membranes (SPMs) that are devoid of organelles from the internal environment of the nerve terminal, such as mitochondria and synaptic vesicles. The isolated SPMs can reseal and form vesicular structures in which transport of ions such as sodium and calcium, as well as solutes such as neurotransmitters can be studied. The PSDs also remain associated with the presynaptic membranes during isolation of SPM fractions, making it possible to isolate the synaptic junctional complexes (SJCs) devoid of the rest of the plasma membranes of the nerve terminals and postsynaptic membrane components. Isolated SJCs can be used to identify the proteins that constitute this highly specialized region of neurons. In this chapter, we describe the steps involved in isolating synaptosomes, SPMs, and SJCs from brain so that these preparations can be used with new technological advances to address many as yet unanswered questions about the synapse and its remarkable activities in neuronal cell communication.
NASA Technical Reports Server (NTRS)
Mohr, P. A.
1974-01-01
ERTS imagery reveals for the first time the structural pattern of the African rift system as a whole. The strong influence of Precambrian structures on this pattern is clearly evident, especially along zones of cataclastic deformation, but the rift pattern is seen to be ultimately independent in origin and nature from Precambrian tectonism. Continuity of rift structures from one swell to another is noted. The widening of the Gregory rift as its northern end reflects an underlying Precambrian structural divergence, and is not a consequence of reaching the swell margin. Although the Western Rift is now proven to terminate at the Aswa Mylonite Zone, in southern Sudan, lineaments extend northeastwards from Lake Albert to the Eastern Rift at Lake Stefanie. The importance of en-echelon structures in the African rifts is seen to have been exaggerated.
NASA Astrophysics Data System (ADS)
2016-02-01
In the Invited Feature Article in this issue of Estuarine, Coastal and Shelf Science, Ruben Kosyan and Violeta Velikova describe the disastrous anthropogenic impact on the Black Sea coast of Bulgaria, Georgia, Romania, Russian Federation, Turkey, and Ukraine over the last 100 years and its inverse correlation with economic development as exemplified by improving water quality during a downturn in the economy. This degradation is now accelerating from the renovation and construction of ports and terminals, the development of resorts, hazardous industrial development, oil and gas exploration, and unsustainable agricultural and fishing practices. There appears to be no enforcement of protected areas. In the absence of scientific research on these issues, coastal zone management appears to be based on 'learning after seeing disastrous effects'. Without recognition of the need for Integrated Coastal Zone Management, the Black Sea coast and the coastal waters will deteriorate, as was observed between the 1970s and the 1990s.
The origin of strike-slip tectonics in continental rifts
NASA Astrophysics Data System (ADS)
Ebinger, C. J.; Pagli, C.; Yun, S. H.; Keir, D.; Wang, H.
2016-12-01
Although continental rifts are zones of lithospheric extension, strike-slip tectonics is also accommodated within rifts and its origin remains controversial. Here we present a combined analysis of recent seismicity, InSAR and GPS derived strain maps to reveal that the plate motion in Afar is accommodated primarily by extensional tectonics in all rift arms and lacks evidences of regional scale bookshelf tectonics. However in the rifts of central Afar we identify crustal extension and normal faulting in the central part of the rifts but strike-slip earthquakes at the rift tips. We investigate if strike-slip can be the result of Coulomb stress changes induced by recent dyking but models do not explain these earthquakes. Instead we explain strike-slips as shearing at the tips of a broad zone of spreading where extension terminates against unstretched lithosphere. Our results demonstrate that plate spreading can develop both strike-slip and extensional tectonics in the same rifts.
Ultrastructural and functional fate of recycled vesicles in hippocampal synapses
Rey, Stephanie A.; Smith, Catherine A.; Fowler, Milena W.; Crawford, Freya; Burden, Jemima J.; Staras, Kevin
2015-01-01
Efficient recycling of synaptic vesicles is thought to be critical for sustained information transfer at central terminals. However, the specific contribution that retrieved vesicles make to future transmission events remains unclear. Here we exploit fluorescence and time-stamped electron microscopy to track the functional and positional fate of vesicles endocytosed after readily releasable pool (RRP) stimulation in rat hippocampal synapses. We show that most vesicles are recovered near the active zone but subsequently take up random positions in the cluster, without preferential bias for future use. These vesicles non-selectively queue, advancing towards the release site with further stimulation in an actin-dependent manner. Nonetheless, the small subset of vesicles retrieved recently in the stimulus train persist nearer the active zone and exhibit more privileged use in the next RRP. Our findings reveal heterogeneity in vesicle fate based on nanoscale position and timing rules, providing new insights into the origins of future pool constitution. PMID:26292808
Seismic anisotropy and slab dynamics from SKS splitting recorded in Colombia
NASA Astrophysics Data System (ADS)
Porritt, Robert W.; Becker, Thorsten W.; Monsalve, Gaspar
2014-12-01
The Nazca, Caribbean, and South America plates meet in northwestern South America where the northern end of the Andean volcanic arc and Wadati-Benioff zone seismicity indicate ongoing subduction. However, the termination of Quaternary volcanism at ~5.5°N and eastward offset in seismicity underneath Colombia suggest the presence of complex slab geometry. To help link geometry to dynamics, we analyze SKS splitting for 38 broadband stations of the Colombian national network. Measurements of fast polarization axes in western Colombia close to the trench show dominantly trench-perpendicular orientations. Orientations measured at stations in the back arc, farther to the east, however, abruptly change to roughly trench parallel anisotropy. This may indicate along-arc mantle flow, possibly related to the suggested "Caldas" slab tear, or a lithospheric signature, but smaller-scale variations in anisotropy remain to be explained. Our observations are atypical globally and challenge our understanding of the complexities of subduction zone seismic anisotropy.
Two-target game model of an air combat with fire-and-forget all-aspect missiles
NASA Technical Reports Server (NTRS)
Davidovitz, A.; Shinar, J.
1989-01-01
An air combat duel between similar aggressive fighter aircraft, both equipped with the same type of guided missiles, is formulated as a two-target differential game using the dynamic model of the game of two identical cars. Each of the identical target sets represents the effective firing envelope of an all-aspect fire-and-forget air-to-air missile. The firing range limits depend on the target aspect angle and are approximated by analytical functions. The maximum range, computed by taking into account the optimal missile avoidance maneuver of the target, determines the no-escape firing envelope. The solution consists of the decomposition of the game space into four regions: the respective winning zones of the two opponents, the draw zone, and the region where the game terminates by a mutual kill. The solution provides a new insight for future air combat analysis.
Park, Sook Kyung; Ko, Sang Jin; Paik, Sang Kyoo; Rah, Jong-Cheol; Lee, Kea Joo; Bae, Yong Chul
2018-02-23
To provide information on the glutamatergic synapses on the trigeminal motoneurons, which may be important for understanding the mechanism of control of jaw movements, we investigated the distribution of vesicular glutamate transporter (VGLUT)1-immunopositive (+) and VGLUT2 + axon terminals (boutons) on the rat jaw-closing (JC) and jaw-opening (JO) motoneurons, and their morphological determinants of synaptic strength by retrograde tracing, electron microscopic immunohistochemistry, and quantitative ultrastructural analysis. We found that (1) the large majority of VGLUT + boutons on JC and JO motoneurons were VGLUT2+, (2) the density of VGLUT1 + boutons terminating on JC motoneurons was significantly higher than that on JO motoneurons, (3) the density of VGLUT1 + boutons terminating on non-primary dendrites of JC motoneurons was significantly higher than that on somata or primary dendrites, whereas the density of VGLUT2 + boutons was not significantly different between JC and JO motoneurons and among various compartments of the postsynaptic neurons, and (4) the bouton volume, mitochondrial volume, and active zone area of the VGLUT1 + boutons forming synapses on JC motoneurons were significantly bigger than those of VGLUT2 + boutons. These findings suggest that JC and JO motoneurons receive glutamatergic input primarily from VGLUT2-expressing intrinsic neurons (premotoneurons), and may be controlled differently by neurons in the trigeminal mesencephalic nucleus and by glutamatergic premotoneurons.
NASA Astrophysics Data System (ADS)
Viglietti, Pia A.; Smith, Roger M. H.; Angielczyk, Kenneth D.; Kammerer, Christian F.; Fröbisch, Jörg; Rubidge, Bruce S.
2016-01-01
The Dicynodon Assemblage Zone (DiAZ) of South Africa's Karoo Basin is one of the eight biostratigraphic zones of the Beaufort Group. It spans the uppermost Permian strata (Balfour, Teekloof, and Normandien formations) and traditionally has been considered to terminate with the disappearance of Dicynodon lacerticeps at the Permo-Triassic Boundary. We demonstrate that the three index fossils currently used to define the Dicynodon Assemblage Zone (Dicynodon lacerticeps, Theriognathus microps, and Procynosuchus delaharpeae) have first appearance datums (FADs) below its traditionally recognized lower boundary and have ranges mostly restricted to the lower portion of the biozone, well below the Permo-Triassic Boundary. We propose re-establishing Daptocephalus leoniceps as an index fossil for this stratigraphic interval, and reinstating the name Daptocephalus Assemblage Zone (DaAZ) for this unit. Furthermore, the FAD of Lystrosaurus maccaigi in the uppermost reaches of the biozone calls for the establishment of a two-fold subdivision of the current Dicynodon Assemblage Zone. The biostratigraphic utility of Da. leoniceps and other South African dicynodontoids outside of the Karoo Basin is limited due to basinal endemism at the species level and varying temporal ranges of dicynodontoids globally. Therefore, we recommend their use only for correlation within the Karoo Basin at this time. Revision of the stratigraphic ranges of all late Permian tetrapods does not reveal a significant change in faunal diversity between the lower and upper DaAZ. However, the last appearance datums of the abundant taxa Di. lacerticeps, T. microps, P. delaharpeae, and Diictodon feliceps occur below the three extinction phases associated with the end-Permian mass extinction event. Due to northward attenuation of the strata, however, the stratigraphic position of the extinction phases may need to be reconsidered.
Diaby, Nouhou; Dold, Bernhard; Pfeifer, Hans-Rudolf; Holliger, Christof; Johnson, D Barrie; Hallberg, Kevin B
2007-02-01
The distribution and diversity of acidophilic bacteria of a tailings impoundment at the La Andina copper mine, Chile, was examined. The tailings have low sulfide (1.7% pyrite equivalent) and carbonate (1.4% calcite equivalent) contents and are stratified into three distinct zones: a surface (0-70-80 cm) 'oxidation zone' characterized by low-pH (2.5-4), a 'neutralization zone' (70-80 to 300-400 cm) and an unaltered 'primary zone' below 400 cm. A combined cultivation-dependent and biomolecular approach (terminal restriction enzyme fragment length polymorphism and 16S rRNA clone library analysis) was used to characterize the indigenous prokaryotic communities in the mine tailings. Total cell counts showed that the microbial biomass was greatest in the top 125 cm of the tailings. The largest numbers of bacteria (10(9) g(-1) dry weight of tailings) were found at the oxidation front (the junction between the oxidation and neutralization zones), where sulfide minerals and oxygen were both present. The dominant iron-/sulfur-oxidizing bacteria identified at the oxidation front included bacteria of the genus Leptospirillum (detected by molecular methods), and Gram-positive iron-oxidizing acidophiles related to Sulfobacillus (identified both by molecular and cultivation methods). Acidithiobacillus ferrooxidans was also detected, albeit in relatively small numbers. Heterotrophic acidophiles related to Acidobacterium capsulatum were found by molecular methods, while another Acidobacterium-like bacterium and an Acidiphilium sp. were isolated from oxidation zone samples. A conceptual model was developed, based on microbiological and geochemical data derived from the tailings, to account for the biogeochemical evolution of the Piuquenes tailings impoundment.
Bacterioplankton Populations within the Oxygen Minimum Zone of the Sargasso Sea
NASA Astrophysics Data System (ADS)
Schuler, G.; Parsons, R. J.; Johnson, R. J.
2016-02-01
Oxygen minimum zones are present throughout the world's oceans, and occur at depths between 200 to 1000m. Heterotrophic bacteria reduce the dissolved oxygen within this layer through respiration, while metabolizing falling particles. This report studied the bacterioplankton in the oxygen minimum zone at the BATS (Bermuda Atlantic Times-series Study) site from July 2014 until November 2014. Total bacterioplankton populations were enumerated through direct counts. In the transitional zone (400m-800m) of the oxygen minimum zone, a secondary bacterioplankton peak formed. This study used FISH (Fluorescent in situ hybridization) and CARD-FISH (Catalyzed Reporter Deposition-Fluorescent in situ hybridization) to enumerate specific bacterial and archaeal taxa. Crenarchaeota (including Thaumarchaeota) increased in abundance within the upper oxycline. Thaumarchaeota have the ammonia monooxygenase gene that oxidizes ammonium into nitrite in low oxygen conditions. Amplification of the amoA gene confirmed that ammonia oxidizing archaea (AOA) were present within the OMZ. Using Terminal Restriction Fragment Length Polymorphism (T-RFLP), the bacterial community structure showed high similarity based depth zones (0-80m, 160-600m, and 800-4500m). Niskin experiments determined that water collected at 800m had an exponential increase in bacterioplankton over time. While experimental design did not allow for oxygen levels to be maintained, the bacterioplankton community was predominantly bacteria with eubacteria positive cells making up 89.3% of the of the total bacterioplankton community by day 34. Improvements to the experimental design are required to determine which specific bacterial taxa caused this increase at 800m. This study suggests that there are factors other than oxygen influencing bacterioplankton populations at the BATS site, and more analysis is needed once the BATS data is available to determine the key drivers of bacterioplankton dynamics within the BATS OMZ.
NASA Astrophysics Data System (ADS)
Meyer, Sven Erik; Passchier, Cees; Abu-Alam, Tamer; Stüwe, Kurt
2014-05-01
Metamorphic core complexes usually develop as extensional features during continental crustal thinning, such as the Basin and Range and the Aegean Terrane. The Najd fault system in Saudi Arabia is a 2000 km-long and 400 km-wide complex network of crustal-scale strike-slip shear zones in a Neoproterozoic collision zone. Locally, the anastomosing shear zones lead to exhumation of lower crustal segments and represent a new kinematic model for the development of core complexes. We report on two such structures: the Qazaz complex in Saudi Arabia and the Hafafit complex in Egypt. The 15 km-wide Qazaz complex is a triangular dome of gently dipping mylonitic foliations within the 140 km-long sinistral strike-slip Qazaz mylonite zone. The gneissic dome consists of high-grade rocks, surrounded by low-grade metasediments and metavolcanics. The main SE-trending strike-slip Qazaz shear zone splits southwards into two branches around the gneiss dome: the western branch is continuous with the shallow dipping mylonites of the dome core, without overprinting, and changes by more than 90 degrees from a NS-trending strike-slip zone to an EW-trending 40 degree south-dipping detachment that bounds the gneiss dome to the south. The eastern SE-trending sinistral strike-slip shear zone branch is slightly younger and transects the central dome fabrics. The gneiss dome appears to have formed along a jog in the strike-slip shear zone during 40 km of horizontal strike-slip motion, which caused local exhumation of lower crustal rocks by 25 km along the detachment. The eastern shear zone branch formed later during exhumation, transacted the gneiss dome and offset the two parts by another 70 km. The Hafafit core complex in Egypt is of similar shape and size to the Qazaz structure, but forms the northern termination of a sinistral strike-slip zone that is at least 100 km in length. This zone may continue into Saudi Arabia as the Ajjaj shear zone for another 100 km. The NW trending strike slip mylonite zone grades into a gently N-dipping detachment to the west which accommodated strike slip by exhumation of high-grade lower crustal rocks. The Qazaz and the Hafafit Domes are similar, mirror-image structures with small differences in the accommodating shear zones. It is likely that these types of strike-slip related oblique core complexes are common in the Arabian Nubian shield, and possibly elsewhere.
Active faults and minor plates in NE Asia
NASA Astrophysics Data System (ADS)
Kozhurin, Andrey I.; Zelenin, Egor A.
2014-05-01
Stated nearly 40 yr ago the uncertainty with plate boundaries location in NE Asia (Chapman, Solomon, 1976) still remains unresolved. Based on the prepositions that a plate boundary must, first, reveal itself in linear sets of active structures, and, second, be continuous and closed, we have undertaken interpretation of medium-resolution KH-9 Hexagon satellite imageries, mostly in stereoscopic regime, for nearly the entire region of NE Asia. Main findings are as follows. There are two major active fault zones in the region north of the Bering Sea. One of them, the Khatyrka-Vyvenka zone, stretches NE to ENE skirting the Bering Sea from the Kamchatka isthmus to the Navarin Cape. Judging by the kinematics of the Olyutorsky 2006 earthquake fault, the fault zones move both right-laterally and reversely. The second active fault zone, the Lankovaya-Omolon zone, starts close to the NE margin of the Okhotsk Sea and extends NE up to nearly the margin of the Chukcha Sea. The fault zone is mostly right-lateral, with topographically expressed cumulative horizontal offsets amounting to 2.5-2.6 km. There may be a third NE-SW zone between the major two coinciding with the Penzhina Range as several active faults found in the southern termination of the Range indicate. The two active fault zones divide the NE Asia area into two large domains, which both could be parts of the Bering Sea plate internally broken and with uncertain western limit. Another variant implies the Khatyrka-Vyvenka zone as the Bering Sea plate northern limit, and the Lankovaya-Omolon zone as separating an additional minor plate from the North-American plate. The choice is actually not crucial, and more important is that both variants leave the question of where the Bering Sea plate boundary is in Alaska. The Lankovaya-Omolon zone stretches just across the proposed northern boundary of the Okhorsk Sea plate. NW of the zone, there is a prominent left-lateral Ulakhan fault, which is commonly interpreted to be a portion of the plate northern boundary. With this, we have discovered no active faults or fault zones of the Ulakhan fault strike, which could be the portion of the boundary between the Lankovaya-Omolon zone and either the western margin of the Komandor basin or the westernmost Aleutians. We conclude that there is a certain disagreement between active faulting pattern and plate models for NE Asia, relating to the extent of the plates and missing portions of the plate boundaries. The research was supported by grant # 110500136-a from the Russian Foundation for Basic Research.
Lepage, D; Parratte, B; Tatu, L; Vuiller, F; Monnier, G
2005-12-01
Hypertonia of the upper limb due to spasticity causes pronation of the forearm and flexion of wrist and fingers. Nowadays this spasticity is often treated with injections of botulinum toxin and sometimes with selective fascicular neurotomy. To correctly perform this microsurgical technique, it is necessary to get precise knowledge of the extramuscular nerve branching in order to be better able to select the motor branches which supply the muscles involved in spasticity. The same knowledge is required for botulinum toxin injections which must be made as near as possible to the zones where intramuscular nerve endings are the densest, which is also where neuromuscular junctions are the most numerous. Thus, it is necessary to better know these zones, but their knowledge remains today imprecise. The muscles of the anterior compartment of 30 forearms were dissected, first macroscopically, then microscopically, to study the extra- and intramuscular nerve supply and the distribution of terminal nerve ramifications. The results were then linked to surface topographical landmarks to indicate the precise location of motor branches for each muscle with the aim of proposing appropriate surgical approaches for selective neurotomies. Then for each muscle, the zones with the highest density of nerve endings were divided into segments, thus determining the optimal zones for botulinim toxin injections.
Loading of the San Andreas fault by flood-induced rupture of faults beneath the Salton Sea
Brothers, Daniel; Kilb, Debi; Luttrell, Karen; Driscoll, Neal W.; Kent, Graham
2011-01-01
The southern San Andreas fault has not experienced a large earthquake for approximately 300 years, yet the previous five earthquakes occurred at ~180-year intervals. Large strike-slip faults are often segmented by lateral stepover zones. Movement on smaller faults within a stepover zone could perturb the main fault segments and potentially trigger a large earthquake. The southern San Andreas fault terminates in an extensional stepover zone beneath the Salton Sea—a lake that has experienced periodic flooding and desiccation since the late Holocene. Here we reconstruct the magnitude and timing of fault activity beneath the Salton Sea over several earthquake cycles. We observe coincident timing between flooding events, stepover fault displacement and ruptures on the San Andreas fault. Using Coulomb stress models, we show that the combined effect of lake loading, stepover fault movement and increased pore pressure could increase stress on the southern San Andreas fault to levels sufficient to induce failure. We conclude that rupture of the stepover faults, caused by periodic flooding of the palaeo-Salton Sea and by tectonic forcing, had the potential to trigger earthquake rupture on the southern San Andreas fault. Extensional stepover zones are highly susceptible to rapid stress loading and thus the Salton Sea may be a nucleation point for large ruptures on the southern San Andreas fault.
Anderson, Robert T.; Lovely, Derek R.
1999-01-01
Naphthalene was oxidized anaerobically to CO2 in sediments collected from a petroleum-contaminated aquifer in Bemidji, Minnesota in which Fe(III) reduction was the terminal electron-accepting process. Naphthalene was not oxidized in sediments from the methanogenic zone at Bemidji or in sediments from the Fe(III)-reducing zone of other petroleum-contaminated aquifers studied. In a profile across the Fe(III)-reducing zone of the Bemidji aquifer, rates of naphthalene oxidation were fastest in sediments with the highest proportion of Fe(III), which was also the zone of the most rapid degradation of benzene, toluene, and acetate. The comparative studies attempted to elucidate factors that might account for the fact that unsubstituted aromatic hydrocarbons such as benzene and naphthalene were degraded under Fe(III)-reducing conditions at Bemidji, but not at the other aquifers examined. These studies indicated that the ability of Fe(III)-reducing microorganisms to degrade benzene and naphthalene at the Bemidji site cannot be attributed to groundwater components that make Fe(III) more available for reduction or other potential factors that were evaluated. However, unlike the other aquifers evaluated, uncontaminated sediments at the Bemidji site could be adapted for anaerobic benzene degradation merely with the addition of benzene. These findings indicate that Bemidji sediments naturally contain Fe(III) reducers capable of degradation of unsubstituted aromatic hydrocarbons.
Reinterpretation of the tectonics and formation of the Pernambuco Plateau Basin, NE Brazil.
NASA Astrophysics Data System (ADS)
Hoggett, Murray; Jones, Stephen M.; Dunkley Jones, Tom; Reston, Timothy; Barbosa, Antonio; Biondo, Vanessa; Mort, Haydon P.
2017-04-01
The continental margin from Alagoas to Natal represents arguably the most frontier region for exploration on the Brazillian margin. High quality seismic data was not collected in the region for many decades as it was believed that only a few kilometers of sediment existed, and thus there was no exploration potential. Here we present the results of work done as part of an IODP virtual site survey. The work has resulted in a total reinterpretation of the basin structure and tectonics, including finding sediment filled half grabens holding up to 8km thick stratigraphic sections. The two deepest grabens likely represent rift jumps during breakup, which may imply different age sediments in the different grabens. The basin is also found to contain a sizable salt accumulation, previously uninterpreted due to hard overlying carbonates hampering seismic imaging. This salt can be seen to have been highly mobile in the past, and has developed into kilometer scale diapirs flanked by typical rollover anticlines. For the first time we show the basin has all the elements needed for a working petroleum system, with the exception a source rock - which cannot be speculated on further as the basin is undrilled. However source rock sequences are present in the Alagoas basin to the south, and recent released seep data show evidence for both biogeneic and thermogenic seeps over the plateau basin, which could also signal source rock presence. We present seismic and potential fields data, including forward potential fields models and seismically derived crustal stretching and thinning estimates, to show that the half grabens terminate abruptly at the latitude of the Pernambuco Shear Zone, a major crustal scale Precambrian shear zone. Onshore boreholes, well away from the deep seismically imaged half grabens offshore, find crystalline basement to drop away rapidly across the shearzone, revealing a third graben to terminate at the shear zone. We interpret this as that the preexisting crustal structure has acted as a mechanical barrier to south to north rift propagation, which has controlled the basin's formation. The shear zone was likely reactivated with a sinistral sense of shear to accommodate rifting, which also helps explain the anomalously wide continental margin at the Pernambuco Plateau.
Connection Zones, Surface Water - Groundwater: Aquifers Associated To Niger Central Delta, In Mali.
NASA Astrophysics Data System (ADS)
Kone, S.
2016-12-01
Surface water infiltration recharging Mali aquifers occurs through, underlying perched hydrogeological networks, lacustrine zones of the Central Delta or inundation valleys. The mapping of both the Surface water and the Groundwater, their types and availabilities, are briefly presented, and the focus of the study is on the types of hydraulic connections between these water bodies. The aquifers hydraulically connected to the Niger Central Delta flows systems are Continental Terminal/Quaternary, and they concern some areas where either inundation or perennial surface water flow occurs. These aquifers belong to the hydrogeological Unit of Central Delta where the recharge by surface water is estimated to be five percent of the flow loss between the entry and the outlet of this hydrological system. Some attempts of simulation along with a review based on the first studies synthetized in "Synthese Hydrogeologique du Mali" would permit to pave the way to other studies on these hydraulically connected zones in Mali. A previews simulation study, about mapping the potential rate of pumping capacity, corroborates some observed structural characteristics and leads to subdivide the area in two hydrogeological sectors, and the present simulation studies focus on the sector "Macina -Diaka" where surface water are in hydraulic relation with groundwater.
The Chara Array Angular Diameter of HR 8799 Favors Planetary Masses for Its Imaged Companions
2012-12-10
because of the shallow convective zones in A-type stars ( Charbonneau 1991). Accretion at these rates will quickly establish abundance anomalies within a...few Myr, but these anomalies will likewise disappear in as little as 1 Myr once the accretion has terminated (Turcotte & Charbonneau 1993); the... Charbonneau , P. 1991, ApJ, 372, L33 Chen, C. H., Sargent, B. A., Bohac, C., et al. 2006, ApJS, 166, 351 Claret, A., & Bloemen, S. 2011, A&A, 529, A75 Cox, A. N
2012-12-01
requirements as part of an overall medical support concept In this document several potential CONOPS proposals are added as food for thought (see Chapter 4...safe flight minimums for manned flight; • En route or terminal environment (landing zone) is contaminated by an industrial spill or by a CBRN event...Further, the U.S. Food and Drug Administration (FDA) and other national/international medical regulatory authorities have requirements for portable
DOE Office of Scientific and Technical Information (OSTI.GOV)
McCulloh, R.P.; Purcell, M.D.
1983-09-01
A regional study of the Tuscaloosa Formation in Louisiana, undertaken to assess geopressured-geothermal potential, revealed lobate, downdip extensions of the hydropressured zone in lower Tuscaloosa massive sandstone facies below the regional top of geopressure. Normal pressure zones within geopressured section were identified by drilling-mud weights less than 13 lb/gal on electric logs of massive lower Tuscaloosa sandstone; cross section demonstrated updip continuity of these zones with the regional hydropressured zone. These hydropressure tongues are permitted by the anomalously high permeabilities reported from the deep Tuscaloosa trend, and they are attributed to both primary and secondary porosity by investigators of Tuscaloosamore » sandstone petrography. The hydropressure tongues correspond with lobes of thick net sandstone, principally in Pointe Coupee, East Felinicana, East Baton Rouge, and Livingston Parishes in the central Tuscaloosa trend. Limited control suggests at least one hydropressure tongue in the Chandeleur Sound area to the east. Dimensions of hydropressure tongues range up to 27 km (17 mi) parallel to srike and 17 km (11 mi) oblique to strike. In many places, tongues are terminated downdip by faults, which, by acting as pressure seals, prevent the tongues from extending to the downdip edge of the massive sandstone in the expanded sections of the downthrown blocks. The areal extent of geopressured Tuscaloosa sandstone is controlled updip by these fault zones, and downdip by pinch-out of the sandstone units basinward. Local hydropressure tongues diminish the geopressured-geothermal potential of the Tuscaloosa trend, but show no discernible relation to gas-productive areas.« less
NASA Astrophysics Data System (ADS)
Maesano, F. E.; Tiberti, M. M.; Basili, R.
2017-12-01
In recent years an increasing number of studies have been focused in understanding the lateral terminations of subduction zones. In the Mediterranean region, this topic is of particular interest for the presence of a "land-locked" system of subduction zones interrupted by continental collision and back-arc opening. We present a 3D reconstruction of the area surrounding the Tindari-Alfeo Fault System (TAFS) based on a dense set of deep seismic reflection profiles. This fault system represents a major NNW-SSE trending subduction-transform edge propagator (STEP) that controls the deformation zone bounding the Calabrian subduction zone (central Mediterranean Sea) to the southwest. This 3D model allowed us to characterize the mechanical and kinematic evolution of the TAFS during the Plio-Quaternary. Our study highlights the presence of a mechanical decoupling between the deformation observed in the lower plate, constituted by the Ionian oceanic crust entering the subduction zone, and the upper plate, where a thick accretionary wedge has formed. The lower plate hosts the master faults of the TAFS, whereas the upper plate is affected by secondary deformation (bending-moment faulting, localized subsidence, stepovers, and restraining/releasing bends). The analysis of the syn-tectonic sedimentary basins related to the activity of the TAFS at depth allow us to constrain the propagation rate of the deformation and of the vertical component of the slip-rate. Our findings provide a comprehensive framework of the structural setting that can be expected along a STEP boundary where contractional and transtensional features coexist at close distance from one another.
Nishimune, Hiroshi; Numata, Tomohiro; Chen, Jie; Aoki, Yudai; Wang, Yonghong; Starr, Miranda P; Mori, Yasuo; Stanford, John A
2012-01-01
The P/Q-type voltage-dependent calcium channels (VDCCs) are essential for synaptic transmission at adult mammalian neuromuscular junctions (NMJs); however, the subsynaptic location of VDCCs relative to active zones in rodent NMJs, and the functional modification of VDCCs by the interaction with active zone protein Bassoon remain unknown. Here, we show that P/Q-type VDCCs distribute in a punctate pattern within the NMJ presynaptic terminals and align in three dimensions with Bassoon. This distribution pattern of P/Q-type VDCCs and Bassoon in NMJs is consistent with our previous study demonstrating the binding of VDCCs and Bassoon. In addition, we now show that the interaction between P/Q-type VDCCs and Bassoon significantly suppressed the inactivation property of P/Q-type VDCCs, suggesting that the Ca(2+) influx may be augmented by Bassoon for efficient synaptic transmission at NMJs. However, presynaptic Bassoon level was significantly attenuated in aged rat NMJs, which suggests an attenuation of VDCC function due to a lack of this interaction between VDCC and Bassoon. Importantly, the decreased Bassoon level in aged NMJs was ameliorated by isometric strength training of muscles for two months. The training increased Bassoon immunoreactivity in NMJs without affecting synapse size. These results demonstrated that the P/Q-type VDCCs preferentially accumulate at NMJ active zones and play essential role in synaptic transmission in conjunction with the active zone protein Bassoon. This molecular mechanism becomes impaired by aging, which suggests altered synaptic function in aged NMJs. However, Bassoon level in aged NMJs can be improved by muscle exercise.
Wahl, Silke; Magupalli, Venkat Giri; Dembla, Mayur; Katiyar, Rashmi; Schwarz, Karin; Köblitz, Louise; Alpadi, Kannan; Krause, Elmar; Rettig, Jens; Sung, Ching-Hwa; Goldberg, Andrew F. X.
2016-01-01
Mutations in the Tulp1 gene cause severe, early-onset retinitis pigmentosa (RP14) in humans. In the retina, Tulp1 is mainly expressed in photoreceptors that use ribbon synapses to communicate with the inner retina. In the present study, we demonstrate that Tulp1 is highly enriched in the periactive zone of photoreceptor presynaptic terminals where Tulp1 colocalizes with major endocytic proteins close to the synaptic ribbon. Analyses of Tulp1 knock-out mice demonstrate that Tulp1 is essential to keep endocytic proteins enriched at the periactive zone and to maintain high levels of endocytic activity close to the synaptic ribbon. Moreover, we have discovered a novel interaction between Tulp1 and the synaptic ribbon protein RIBEYE, which is important to maintain synaptic ribbon integrity. The current findings suggest a new model for Tulp1-mediated localization of the endocytic machinery at the periactive zone of ribbon synapses and offer a new rationale and mechanism for vision loss associated with genetic defects in Tulp1. SIGNIFICANCE STATEMENT Mutations in the Tulp1 gene cause severe, early-onset retinitis pigmentosa (RP14) and Leber congenital amaurosis (LCA15) in human patients. In this study, we discovered that the phosphoinositol-4,5-bisphosphate-binding protein Tulp1 is essential for the structural and functional organization of the periactive zone in photoreceptor synapses. Using Tulp1 knock-out mice, we found that Tulp1 is required to enrich major endocytic proteins at the periactive zone next to the synaptic ribbon. We demonstrate that Tulp1 is needed to promote endocytic vesicle retrieval at the periactive zone. Moreover, we discovered a novel interaction between Tulp1 and the synaptic ribbon protein RIBEYE. This newly discovered disease-sensitive interaction provides a molecular model for the control of endocytosis close to the synaptic ribbon. PMID:26911694
Russotto, Vincenzo; Cortegiani, Andrea; Fasciana, Teresa; Iozzo, Pasquale; Raineri, Santi Maurizio; Gregoretti, Cesare; Giammanco, Anna; Giarratano, Antonino
2017-01-01
Intensive care unit- (ICU-) acquired infections are a major health problem worldwide. Inanimate surfaces and equipment contamination may play a role in cross-transmission of pathogens and subsequent patient colonization or infection. Bacteria contaminate inanimate surfaces and equipment of the patient zone and healthcare area, generating a reservoir of potential pathogens, including multidrug resistant species. Traditional terminal cleaning methods have limitations. Indeed patients who receive a bed from prior patient carrying bacteria are exposed to an increased risk (odds ratio 2.13, 95% confidence intervals 1.62-2.81) of being colonized and potentially infected by the same bacterial species of the previous patient. Biofilm formation, even on dry surfaces, may play a role in reducing the efficacy of terminal cleaning procedures since it enables bacteria to survive in the environment for a long period and provides increased resistance to commonly used disinfectants. No-touch methods (e.g., UV-light, hydrogen peroxide vapour) are under investigation and further studies with patient-centred outcomes are needed, before considering them the standard of terminal cleaning in ICUs. Healthcare workers should be aware of the role of environmental contamination in the ICU and consider it in the broader perspective of infection control measures and stewardship initiatives.
NASA Astrophysics Data System (ADS)
Belyaev, G.; Boychev, B.; Kostin, V.; Trushkina, E.; Ovcharenko, O.
2015-03-01
Earlier by the authors according to the Intercosmos Bulgaria-1300 and Cosmos-1809 satellite data it's been shown that the ionosphere is modified above the tropical cyclones (TC). Local perturbations of the plasma density, the appearance of the electric fields and the development of ELF-VLF zone of turbulence were observed. These effects were due to the injection of up stream of neutral particles from TC. In this paper the data of the Cosmos-1809 satellite when tropical cyclone Harry (1989) passed through the island of New Caledonia was examined. Influence of evening and morning terminators on the structure of the ionosphere from TC was discussed. It is detected: 1 - the appearance of latitude belt (up to 5000km) of structured perturbations in the night ionosphere; 2 - simulation in the illuminated ionosphere of periodic oscillation of the electric field with a scale ~ 400 km, passing beyond plasma pause. Model for the formation above TC in the lower ionosphere vertical submerged jet that injects neutral particles of different varieties into the upper ionosphere on ballistic trajectories was proposed. Changing of the ionization of neutral particles near the terminator and the deviation of the jet under the interaction of the TC with the island are confirmed in the proposed model.
Pamučar, Dragan; Vasin, Ljubislav; Atanasković, Predrag; Miličić, Milica
2016-01-01
The paper herein presents green p-median problem (GMP) which uses the adaptive type-2 neural network for the processing of environmental and sociological parameters including costs of logistics operators and demonstrates the influence of these parameters on planning the location for the city logistics terminal (CLT) within the discrete network. CLT shows direct effects on increment of traffic volume especially in urban areas, which further results in negative environmental effects such as air pollution and noise as well as increased number of urban populations suffering from bronchitis, asthma, and similar respiratory infections. By applying the green p-median model (GMM), negative effects on environment and health in urban areas caused by delivery vehicles may be reduced to minimum. This model creates real possibilities for making the proper investment decisions so as profitable investments may be realized in the field of transport infrastructure. The paper herein also includes testing of GMM in real conditions on four CLT locations in Belgrade City zone. PMID:27195005
Pamučar, Dragan; Vasin, Ljubislav; Atanasković, Predrag; Miličić, Milica
2016-01-01
The paper herein presents green p-median problem (GMP) which uses the adaptive type-2 neural network for the processing of environmental and sociological parameters including costs of logistics operators and demonstrates the influence of these parameters on planning the location for the city logistics terminal (CLT) within the discrete network. CLT shows direct effects on increment of traffic volume especially in urban areas, which further results in negative environmental effects such as air pollution and noise as well as increased number of urban populations suffering from bronchitis, asthma, and similar respiratory infections. By applying the green p-median model (GMM), negative effects on environment and health in urban areas caused by delivery vehicles may be reduced to minimum. This model creates real possibilities for making the proper investment decisions so as profitable investments may be realized in the field of transport infrastructure. The paper herein also includes testing of GMM in real conditions on four CLT locations in Belgrade City zone.
NASA Technical Reports Server (NTRS)
Young, Larry A.; Rajagopalan, Ganesh
2013-01-01
A mid-fidelity computational fluid dynamics tool called RotCFD - specifically developed to aid in rotorcraft conceptual design efforts - has been applied to the study of rotor wake interactions of civil tiltrotor aircraft in the immediate vicinity of vertiport/airport ground infrastructure. This issue has grown in importance as previous NASA studies have suggested that civil tiltrotor aircraft can potentially have a significant impact on commercial transport aviation. Current NASA reference designs for such civil tiltrotor aircraft are focused on a size category of 90-120 passengers. Notional concepts of operations include simultaneous non-interfering flight into and out of congested airports having vertiports, that is, prepared VTOL takeoff and landing zones, or underutilized short runways for STOL operation. Such large gross-weight vehicles will be generating very high induced velocities. Inevitably, the interaction of the rotor wake with ground infrastructure such as terminals/jetways must be considered both from an operational as well as design perspective.
Varga, R.J.; Faulds, J.E.; Snee, L.W.; Harlan, S.S.; Bettison-Varga, L.
2004-01-01
Recent studies demonstrate that rifts are characterized by linked tilt domains, each containing a consistent polarity of normal faults and stratal tilt directions, and that the transition between domains is typically through formation of accommodation zones and generally not through production of throughgoing transfer faults. The mid-Miocene Black Mountains accommodation zone of southern Nevada and western Arizona is a well-exposed example of an accommodation zone linking two regionally extensive and opposing tilt domains. In the southeastern part of this zone near Kingman, Arizona, east dipping normal faults of the Whipple tilt domain and west dipping normal faults of the Lake Mead domain coalesce across a relatively narrow region characterized by a series of linked, extensional folds. The geometry of these folds in this strike-parallel portion of the accommodation zone is dictated by the geometry of the interdigitating normal faults of opposed polarity. Synclines formed where normal faults of opposite polarity face away from each other whereas anticlines formed where the opposed normal faults face each other. Opposed normal faults with small overlaps produced short folds with axial trends at significant angles to regional strike directions, whereas large fault overlaps produce elongate folds parallel to faults. Analysis of faults shows that the folds are purely extensional and result from east/northeast stretching and fault-related tilting. The structural geometry of this portion of the accommodation zone mirrors that of the Black Mountains accommodation zone more regionally, with both transverse and strike-parallel antithetic segments. Normal faults of both tilt domains lose displacement and terminate within the accommodation zone northwest of Kingman, Arizona. However, isotopic dating of growth sequences and crosscutting relationships show that the initiation of the two fault systems in this area was not entirely synchronous and that west dipping faults of the Lake Mead domain began to form between 1 m.y. to 0.2 m.y. prior to east dipping faults of the Whipple domain. The accommodation zone formed above an active and evolving magmatic center that, prior to rifting, produced intermediate-composition volcanic rocks and that, during rifting, produced voluminous rhyolite and basalt magmas. Copyright 2004 by the American Geophysical Union.
Tectonics of the Jemez Lineament in the Jemez Mountains and Rio Grande Rift
NASA Astrophysics Data System (ADS)
Aldrich, M. J., Jr.
1986-02-01
The Jemez lineament is a NE trending crustal flaw that controlled volcanism and tectonism in the Jemez Mountains and the Rio Grande rift zone. The fault system associated with the lineament in the rift zone includes, from west to east, the Jemez fault zone southwest of the Valles-Toledo caldera complex, a series of NE trending faults on the resurgent dome in the Valles caldera, a structural discontinuity with a high fracture intensity in the NE Jemez Mountains, and the Embudo fault zone in the Española Basin. The active western boundary faulting of the Española Basin may have been restricted to the south side of the lineament since the mid-Miocene. The faulting apparently began on the Sierrita fault on the east side of the Nacimiento Mountains in the late Oligocene and stepped eastward in the early Miocene to the Canada de Cochiti fault zone. At the end of the Miocene (about 5 Ma) the active boundary faulting again stepped eastward to the Pajarito fault zone on the east side of the Jemez Mountains. The north end of the Pajarito fault terminates against the Jemez lineament at a point where it changes from a structural discontinuity (zone of high fracture intensity) on the west to the Embudo fault zone on the east. Major transcurrent movement occurred on the Embudo fault zone during the Pliocene and has continued at a much slower rate since then. The relative sense of displacement changes from right slip on the western part of the fault zone to left slip on the east. The kinematics of this faulting probably reflect the combined effects of faster spreading in the Española Basin than the area north of the lineament (Abiquiu embayment and San Luis Basin), the right step in the rift that juxtaposes the San Luis Basin against the Picuris Mountains, and counterclockwise rotation of various crustal blocks within the rift zone. No strike-slip displacements have occurred on the lineament in the central and eastern Jemez Mountains since at least the mid-Miocene, although movements on the still active Jemez fault zone, in the western Jemez Mountains, may have a significant strike-slip component. Basaltic volcanism was occurring in the Jemez Mountains at four discrete vent areas on the lineament between about 15 Ma and 10 Ma and possibly as late as 7 Ma, indicating that it was being extended during that time.
Changes in biogenic and detrital fluxes across the last two glacial terminations at the Shatsky Rise
NASA Astrophysics Data System (ADS)
Bradtmiller, L. I.; Kinsley, C. W.; McGee, D.; Ford, H. L.; Perala-Dewey, J.; Zhang, Y.
2017-12-01
The Shatsky Rise is located within strong gradients in SST and biological productivity between the subtropical and subarctic Pacific gyres. The region is highly sensitive to changes in atmospheric and oceanic circulation on glacial-interglacial timescales, which affect the delivery of Fe-bearing dust and other major nutrients, respectively. Here we use a range of proxies in an attempt to determine the effects of changes in westerly winds and gyre boundaries on dust delivery and biological productivity. We present 230Th-normalized fluxes of opal, Corg, CaCO3, and detrital material at ODP Site 1208 over the last two glacial terminations, extending to 145ka. Opal, Corg, and carbonate are products of surface biological productivity, while most detrital material at this site arrives in the form of windborne East Asian dust. In addition, we calculate the concentration of authigenic U as an indicator of relative oxygenation of the sediment water interface. We observe elevated opal and dust fluxes during the last two glacial maxima, and a decrease in both components during deglaciations. Authigenic U shows distinct peaks at the onset of both terminations. The peak at the penultimate deglaciation is also associated with a large peak in opal flux, while the peak in authigenic U during the last termination does not appear to be associated with any large changes in biogenic fluxes. We compare our records with other data from the subtropical-subarctic transition zone, and suggest that our data are consistent with northward shift of the mean position of the westerly jet and subarctic front during deglaciations.
NASA Astrophysics Data System (ADS)
Chakraborty, Suman; Sasmal, Sudipta; Basak, Tamal; Ghosh, Soujan; Palit, Sourav; Chakrabarti, Sandip K.; Ray, Suman
2017-10-01
We present perturbations due to seismo-ionospheric coupling processes in propagation characteristics of sub-ionospheric Very Low Frequency (VLF) signals received at Ionospheric & Earthquake Research Centre (IERC) (Lat. 22.50°N, Long. 87.48°E), India. The study is done during and prior to an earthquake of Richter scale magnitude M = 7.3 occurring at a depth of 18 km at southeast of Kodari, Nepal on 12 May 2015 at 12:35:19 IST (07:05:19 UT). The recorded VLF signal of Japanese transmitter JJI at frequency 22.2 kHz (Lat. 32.08°N, Long. 130.83°E) suffers from strong shifts in sunrise and sunset terminator times towards nighttime starting from three to four days prior to the earthquake. The signal shows a similar variation in terminator times during a major aftershock of magnitude M = 6.7 on 16 May, 2015 at 17:04:10 IST (11:34:10 UT). These shifts in terminator times is numerically modeled using Long Wavelength Propagation Capability (LWPC) Programme. The unperturbed VLF signal is simulated by using the day and night variation of reflection height (h‧) and steepness parameter (β) fed in LWPC for the entire path. The perturbed signal is obtained by additional variation of these parameters inside the earthquake preparation zone. It is found that the shift of the terminator time towards nighttime happens only when the reflection height is increased. We also calculate electron density profile by using the Wait's exponential formula for specified location over the propagation path.
Lunardi, N; Oklopcic, A; Prillaman, M; Erisir, A; Jevtovic-Todorovic, V
2015-10-01
Exposure to general anesthesia (GA) during critical stages of brain development induces widespread neuronal apoptosis and causes long-lasting behavioral deficits in numerous animal species. Although several studies have focused on the morphological fate of neurons dying acutely by GA-induced developmental neuroapoptosis, the effects of an early exposure to GA on the surviving synapses remain unclear. The aim of this study is to study whether exposure to GA disrupts the fine regulation of the dynamic spatial organization and trafficking of synaptic vesicles in presynaptic terminals. We exposed postnatal day 7 (PND7) rat pups to a clinically relevant anesthetic combination of midazolam, nitrous oxide, and isoflurane and performed a detailed ultrastructural analysis of the synaptic vesicle architecture at presynaptic terminals in the subiculum of rats at PND 12. In addition to a significant decrease in the density of presynaptic vesicles, we observed a reduction of docked vesicles, as well as a reduction of vesicles located within 100 nm from the active zone, in animals 5 days after an initial exposure to GA. We also found that the synaptic vesicles of animals exposed to GA are located more distally with respect to the plasma membrane than those of sham control animals and that the distance between presynaptic vesicles is increased in GA-exposed animals compared to sham controls. We report that exposure of immature rats to GA during critical stages of brain development causes significant disruption of the strategic topography of presynaptic vesicles within the nerve terminals of the subiculum.
Earth Observations taken by the Expedition 27 Crew
2011-04-12
ISS027-E-012224 (12 April 2011) --- Sunset over western South America is featured in this image photographed by an Expedition 27 crew member on the International Space Station. Crew members onboard the space station see, on average, sixteen sunrises and sunsets during a 24-hour orbital period. Each changeover between day and night on the ground is marked by the terminator, or line separating the sunlit side of Earth from the side in darkness. While the terminator is conceptualized as a hard boundary?and is frequently presented as such in graphics and visualizations?in reality the boundary between light and dark is diffuse due to scattering of light by Earth?s atmosphere. This zone of diffuse lighting is experienced as dusk or twilight on the ground ? while the sun is no longer visible, some illumination is still present due to light scattering over the local horizon. The terminator is visible in this photograph trending across the image from lower left to upper right. This panoramic view across central South America, looking towards the northeast, was acquired at approximately 7:37 p.m. local time. Layers of Earth?s atmosphere, colored bright white to deep blue, are visible extending across the horizon (or limb). The highest cloud tops have a reddish glow from the direct light of the setting sun while lower clouds are in twilight. The Salar de Coipasa, a large salt lake in Bolivia, is dimly visible on the night side of the terminator. The salar provides a geographic reference point that allows the location and viewing orientation of the image to be determined.
Integration of the Second Messenger c-di-GMP into the Chemotactic Signaling Pathway
Russell, Matthew H.; Bible, Amber N.; Fang, Xin; Gooding, Jessica R.; Campagna, Shawn R.; Gomelsky, Mark; Alexandre, Gladys
2013-01-01
ABSTRACT Elevated intracellular levels of the bacterial second messenger c-di-GMP are known to suppress motility and promote sessility. Bacterial chemotaxis guides motile cells in gradients of attractants and repellents over broad concentration ranges, thus allowing bacteria to quickly adapt to changes in their surroundings. Here, we describe a chemotaxis receptor that enhances, as opposed to suppresses, motility in response to temporary increases in intracellular c-di-GMP. Azospirillum brasilense’s preferred metabolism is adapted to microaerophily, and these motile cells quickly navigate to zones of low oxygen concentration by aerotaxis. We observed that changes in oxygen concentration result in rapid changes in intracellular c-di-GMP levels. The aerotaxis and chemotaxis receptor, Tlp1, binds c-di-GMP via its C-terminal PilZ domain and promotes persistent motility by increasing swimming velocity and decreasing swimming reversal frequency, which helps A. brasilense reach low-oxygen zones. If c-di-GMP levels remain high for extended periods, A. brasilense forms nonmotile clumps or biofilms on abiotic surfaces. These results suggest that association of increased c-di-GMP levels with sessility is correct on a long-term scale, while in the short-term c-di-GMP may actually promote, as opposed to suppress, motility. Our data suggest that sensing c-di-GMP by Tlp1 functions similar to methylation-based adaptation. Numerous chemotaxis receptors contain C-terminal PilZ domains or other sensory domains, suggesting that intracellular c-di-GMP as well as additional stimuli can be used to modulate adaptation of bacterial chemotaxis receptors. PMID:23512960
DOE Office of Scientific and Technical Information (OSTI.GOV)
Berger, B.R.; Snee, L.W.
1992-01-01
The Kettle dome, northeastern Washington and southern British Columbia, is one of several large metamorphic core complexes in the region. New Ar-40/Ar-39 cooling dates from the mylonite immediately beneath the Kettle River detachment fault at Barney's Junction, a cross-cutting mafic dike, and the youngest Eocene lavas in the Republic graben set constraints on kinematic models of the tectonic evolution of the dome and related grabens: Amphibolite--hornblende (59.0 [+-] 0.2); Pegmatite--muscovite (49.3 [+-] 0.2); Pegmatite--K-feldspar (49.2 [+-] 1); Augen gneiss--K-feldspar (48.0 [+-] 1); Mafic dike--hornblende (54.5 [+-] 0.1) and biotite (49.6 [+-] 0.1); Klondike Mt. Formation lava--feeder dike (48.8 [+-] 1).more » The authors interpret the dates to indicate that the tectonized amphibolite, part of a Cretaceous and older metamorphosed terrane, had formed and cooled to [approx] 500 C by Late Paleocene, the mylonite zone was being domed above the ductile zone by Early Eocene at the time of emplacement of the dike--temporally equivalent to the Keller Butte suite, Eocene Colville batholith--which crosscuts the mylonite, and incipient rifting was occurring in the Republic graben as evidenced by dike swarms. The mylonite complex reached 300 C by 49Ma coincident with the termination of Sanpoil volcanism, and then cooled rapidly to near or below 150 C by 48 Ma. At about this time, mafic Klondike Mt. lavas mark the termination of Republic graben rifting and possibly detachment faulting along the Kettle River fault.« less
ELF propagation in the presence of nonstratified ionospheric disturbances
NASA Astrophysics Data System (ADS)
Field, E. C., Jr.; Gayer, S. J.; Dambrosio, B. P.
1980-06-01
This report analyzes the propagation of the TEM-ELF waveguide mode when the ionosphere is not stratified. It treats strong localized ionospheric disturbances by recasting the lateral wave equation as a two dimensional integral equation, and applies a specially developed algorithm to obtain numerical solutions. The quasi-full wave results show that a localized ionospheric disturbance behaves like a converging cylindrical lens filling a narrow aperture. Lateral diffraction and focusing, ignored in treatments that do not fully account for transverse ionospheric structure, cause the ELF signal to exhibit a pattern of maxima and minima on the line normal to the path passing through the center of the disturbance. As expected, the focusing/diffraction effects diminish when the transverse dimension of the disturbance exceeds the width of the first Fresnel zone - typically, several megameters. The analysis models widespread inhomogeneities, such as within the polar cap or at the day/night terminator, as semiinfinite regions separated by diffuse boundaries; it then derives full-wave analytic expressions for the reflection of the TEM mode. Mode reflection is found to significantly affect an ELF signal in two actual situations: first, when receivers are on great circle paths that are nearly tangential to the disturbed polar cap - in which case shadow zones and interference patterns can occur; and second, when signals are incident on the day/night terminator (from the day side) at angles exceeding about 75 deg - in which case the signals are affected by a phenomenon analogous to total internal reflection. Reflection is found to be unimportant if the boundary thickness exceeds about one-sixth of a wavelength.
Remote Measurement of Atmospheric Temperatures By Raman Lidar
NASA Technical Reports Server (NTRS)
Salzman, Jack A.; Coney, Thom A.
1973-01-01
The Raman shifted return of a lidar, or optical radar, system has been utilized to make atmospheric temperature measurements. These measurements were made along a horizontal path at temperatures between -20 C and +30 C and at ranges of about 100 meters. The temperature data were acquired by recording the intensity ratio of two portions of the Raman spectrum which were simultaneously sampled from a preset range. The lidar unit employed in this testing consisted of a 4 joule-10ppm laser operating at 694.3 nm, a 10-inch Schmidt-Cassegrain telescope, and a system of time-gated detection and signal processing electronics. The detection system processed three return signal wavelength intervals - two intervals along the rotational Raman scattered spectrum and one interval centered at the Rayleigh-Mie scattered wavelength. The wavelength intervals were resolved by using a pellicle beam splitter and three optical interference filters. Raman return samples were taken from one discrete range segment during each test shot and the signal intensities were displayed in digital format. The Rayleigh-Mie techniques. The test site utilized to evaluate this measurement technique encompassed a total path length of 200 meters. Major components of the test site included a trailer-van housing the lidar unit, a controlled environment test zone, and a beam terminator. The control zone which was located about 100 meters from the trailer was 12 meters in length, 2.4 meters in diameter, and was equipped with hinged doors at each end. The temperature of the air inside the zone could be either raised or lowered with respect to ambient air through the use of infrared heaters or a liquid-nitrogen cooling system. Conditions inside the zone were continuously monitored with a thermocouple rake assembly. The test path length was terminated by a 1.2 meter square array of energy absorbing cones and a flat black screen. Tests were initially conducted at strictly ambient conditions utilizing the normal outside air temperatures as a test parameter. These tests provided a calibration of the Raman intensity ratio as a function of' temperature for the particular optical-filter arrangement used in this system while also providing a test of' the theoretical prediction formulated in the design of the system. Later tests utilized zone temperatures above and below ambient to provide temperature gradient data. These tests indicate that ten shots, or one minute of' data acquisition, from a 100 meter range can provide absolute temperature measurements with an accuracy of + 30 C and a range resolution of about 5 meters. Because this measurement accuracy compares well with that predicted for this particular unit, it is suggested that a field-application system could be built with signif'icant improvements in both absolute accuracy and range.
NASA Astrophysics Data System (ADS)
Peters, Jared L.; Benetti, Sara; Dunlop, Paul; Ó Cofaigh, Colm; Moreton, Steven G.; Wheeler, Andrew J.; Clark, Christopher D.
2016-05-01
The last British-Irish Ice Sheet (BIIS) had extensive marine-terminating margins and was drained by multiple large ice streams and is thus a useful analogue for marine-based areas of modern ice sheets. However, despite recent advances from investigating the offshore record of the BIIS, the dynamic history of its marine margins, which would have been sensitive to external forcing(s), remain inadequately understood. This study is the first reconstruction of the retreat dynamics and chronology of the western, marine-terminating, margin of the last (Late Midlandian) BIIS. Analyses of shelf geomorphology and core sedimentology and chronology enable a reconstruction of the Late Midlandian history of the BIIS west of Ireland, from initial advance to final retreat onshore. Five AMS radiocarbon dates from marine cores constrain the timing of retreat and associated readvances during deglaciation. The BIIS advanced without streaming or surging, depositing a bed of highly consolidated subglacial traction till, and reached to within ∼20 km of the shelf break by ∼24,000 Cal BP. Ice margin retreat was likely preceded by thinning, grounding zone retreat and ice shelf formation on the outer shelf by ∼22,000 Cal BP. This ice shelf persisted for ≤2500 years, while retreating at a minimum rate of ∼24 m/yr and buttressing a >150-km long, 20-km wide, bathymetrically-controlled grounding zone. A large (∼150 km long), arcuate, flat-topped grounding-zone wedge, termed here the Galway Lobe Grounding-Zone Wedge (GLGZW), was deposited below this ice shelf and records a significant stillstand in BIIS retreat. Geomorphic relationships indicate that the BIIS experienced continued thinning during its retreat across the shelf, which led to increased topographic influence on its flow dynamics following ice shelf break up and grounding zone retreat past the GLGZW. At this stage of retreat the western BIIS was comprised of several discrete, asynchronous lobes that underwent several readvances. Sedimentary evidence of dilatant till deposition suggests that the readvances may have been rapid and possibly associated with ice streaming or surging. The largest lobe extended offshore from Galway Bay and deposited the Galway Lobe Readvance Moraine by <18,500 Cal BP. Further to the north, an ice lobe readvanced at least 50 km offshore from Killary Harbour, possibly by ≤15,100 Cal BP. The existing chronology currently does not allow us to determine conclusively whether these readvances were a glaciodynamic (internally-driven) response of the ice sheet during deglaciation or were climatically-driven. Following the <18,500 Cal BP readvance, the Galway Lobe experienced accelerated eastward retreat at an estimated rate of ∼113 m/yr.
Graviresponsiveness of surgically altered primary roots of Zea mays
NASA Technical Reports Server (NTRS)
Maimon, E.; Moore, R.
1991-01-01
We examined the gravitropic responses of surgically altered primary roots of Zea mays to determine the route by which gravitropic inhibitors move from the root tip to the elongating zone. Horizontally oriented roots, from which a 1-mm-wide girdle of epidermis plus 2-10 layers of cortex were removed from the apex of the elongating zone, curve downward. However, curvature occurred only apical to the girdle. Filling the girdle with mucilage-like material transmits curvature beyond the girdle. Vertically oriented roots with a half-girdle' (i.e. the epidermis and 2-10 layers of the cortex removed from half of the circumference of the apex of the elongating zone) curve away from the girdle. Inserting the half-girdle at the base of the elongating zone induces curvature towards the girdle. Filling the half-circumference girdles with mucilage-like material reduced curvature significantly. Stripping the epidermis and outer 2-5 layers of cortex from the terminal 1.5 cm of one side of a primary root induces curvature towards the cut, irrespective of the root's orientation to gravity. This effect is not due to desiccation since treated roots submerged in water also curved towards their cut surface. Coating a root's cut surface with a mucilage-like substance minimizes curvature. These results suggest that the outer cell-layers of the root, especially the epidermis, play an important role in root gravicurvature, and the gravitropic signals emanating from the root tip can move apoplastically through mucilage.
Crone, A.J.; Harding, S.T.; Russ, D.P.; Shedlock, K.M.
1986-01-01
Three major seismic-reflection programs have been conducted by the USGS in the New Madrid seismic zone. The first program consisted of 32 km of conventional Vibroseis profiling designed to investigate the subsurface structure associated with scarps and lineaments in northwestern Tennessee (Zoback, 1979). A second, more extensive Vibroseis program collected about 250 km of data from all parts of the New Madrid seismic zone in Missouri, Arkansas, and Tennessee (Hamilton and Zoback, 1979, 1982; Zoback and others, 1980). The profiles presented here are part of the third program that collected about 240 km of high-resolution seismic-reflection data from a boat along the Mississippi River between Osceola, Ark., and Wickliffe, Ky. (fig. 1). The data for profiles A, B, C, and D were collected between river miles 839-1/2 and 850-1/2 from near the Interstate-155 bridge to upstream of Caruthersville, Mo. (fig. 2). Profiles on this part of the river are important for three reasons: (1) they connect many of the land-based profiles on either side of the river, (2) they are near the northeast termination of a linear, 120km-long, northeast-southwest zone of seismicity that extends from northeast Arkansas to Caruthersville, Mo. (Stauder, 1982; fig. 1), and (3) they cross the southwesterly projection of the Cottonwood Grove fault (fig. 1), a fault having a substantial amount of vertical Cenozoic offset (Zoback and others, 1980).
Wu, Zhencai; Burns, Jacqueline K
2004-07-01
beta-galactosidases have been detected in a wide range of plants and are characterized by their ability to hydrolyse terminal non-reducing beta-D-galactosyl residues from beta-D-galactosides. These enzymes have been detected in a wide range of plant organs and tissues. In a search for differentially expressed genes during the abscission process in citrus, sequences encoding beta-galactosidase were identified. Three cDNA fragments of a beta-galactosidase gene were isolated from a cDNA subtraction library constructed from mature fruit abscission zones 48 h after the application of a mature fruit-specific abscission agent, 5-chloro-3-methyl-4-nitro-1H-pyrazole (CMN-pyrazole). Based on sequence information derived from these fragments, a full-length cDNA of 2847 nucleotides (GenBank accession number AY029198) encoding beta-galactosidase was isolated from mature fruit abscission zones by 5'- and 3'-RACE approaches. The beta-galactosidase cDNA encoded a protein of 737 amino acid residues with a calculated molecular weight of 82 kDa. The deduced protein was highly homologous to plant beta-galactosidases expressed in fruit ripening. Southern blot analysis demonstrated that at least two closely related beta-galactosidase genes were present in 'Valencia' orange. Temporal expression patterns in mature fruit abscission zones indicated beta-galactosidase mRNA was detected 48 h after treatment of CMN-pyrazole and ethephon in mature fruit abscission zones. beta-galactosidase transcripts were detected in leaf abscission zones only after ethephon application. The citrus beta-galactosidase was expressed in stamens and petals of fully opened flowers and young fruitlets. The results suggest that this beta-galactosidase may play a role during abscission as well as early growth and development processes in flowers and fruitlets.
What role did the Hikurangi subduction zone play in the M7.8 Kaikoura earthquake?
NASA Astrophysics Data System (ADS)
Wallace, L. M.; Hamling, I. J.; Kaneko, Y.; Fry, B.; Clark, K.; Bannister, S. C.; Ellis, S. M.; Francois-Holden, C.; Hreinsdottir, S.; Mueller, C.
2017-12-01
The 2016 M7.8 Kaikoura earthquake ruptured at least a dozen faults in the northern South Island of New Zealand, within the transition from the Hikurangi subduction zone (in the North Island) to the transpressive Alpine Fault (in the central South Island). The role that the southern end of the Hikurangi subduction zone played (or did not play) in the Kaikoura earthquake remains one of the most controversial aspects of this spectacularly complex earthquake. Investigations using near-field seismological and geodetic data suggest a dominantly crustal faulting source for the event, while studies relying on teleseismic data propose that a large portion of the moment release is due to rupture of the Hikurangi subduction interface beneath the northern South Island. InSAR and GPS data also show that a large amount of afterslip (up to 0.5 m) occurred on the subduction interface beneath the crustal faults that ruptured in the M7.8 earthquake, during the months following the earthquake. Modeling of GPS velocities for the 20 year period prior to the earthquake indicate that interseismic coupling was occurring on the Hikurangi subduction interface beneath the northern South Island, in a similar location to the suggested coseismic and postseismic slip on the subduction interface. We will integrate geodetic, seismological, tsunami, and geological observations in an attempt to balance the seemingly conflicting views from local and teleseismic data regarding the role that the southern Hikurangi subduction zone played in the earthquake. We will also discuss the broader implications of the observed coseismic and postseismic deformation for understanding the kinematics of the southern termination of the Hikurangi subduction zone, and its role in the transition from subduction to strike-slip in the central New Zealand region.
Meta-omic signatures of microbial metal and nitrogen cycling in marine oxygen minimum zones
Glass, Jennifer B.; Kretz, Cecilia B.; Ganesh, Sangita; Ranjan, Piyush; Seston, Sherry L.; Buck, Kristen N.; Landing, William M.; Morton, Peter L.; Moffett, James W.; Giovannoni, Stephen J.; Vergin, Kevin L.; Stewart, Frank J.
2015-01-01
Iron (Fe) and copper (Cu) are essential cofactors for microbial metalloenzymes, but little is known about the metalloenyzme inventory of anaerobic marine microbial communities despite their importance to the nitrogen cycle. We compared dissolved O2, NO3−, NO2−, Fe and Cu concentrations with nucleic acid sequences encoding Fe and Cu-binding proteins in 21 metagenomes and 9 metatranscriptomes from Eastern Tropical North and South Pacific oxygen minimum zones and 7 metagenomes from the Bermuda Atlantic Time-series Station. Dissolved Fe concentrations increased sharply at upper oxic-anoxic transition zones, with the highest Fe:Cu molar ratio (1.8) occurring at the anoxic core of the Eastern Tropical North Pacific oxygen minimum zone and matching the predicted maximum ratio based on data from diverse ocean sites. The relative abundance of genes encoding Fe-binding proteins was negatively correlated with O2, driven by significant increases in genes encoding Fe-proteins involved in dissimilatory nitrogen metabolisms under anoxia. Transcripts encoding cytochrome c oxidase, the Fe- and Cu-containing terminal reductase in aerobic respiration, were positively correlated with O2 content. A comparison of the taxonomy of genes encoding Fe- and Cu-binding vs. bulk proteins in OMZs revealed that Planctomycetes represented a higher percentage of Fe genes while Thaumarchaeota represented a higher percentage of Cu genes, particularly at oxyclines. These results are broadly consistent with higher relative abundance of genes encoding Fe-proteins in the genome of a marine planctomycete vs. higher relative abundance of genes encoding Cu-proteins in the genome of a marine thaumarchaeote. These findings highlight the importance of metalloenzymes for microbial processes in oxygen minimum zones and suggest preferential Cu use in oxic habitats with Cu > Fe vs. preferential Fe use in anoxic niches with Fe > Cu. PMID:26441925
Meta-omic signatures of microbial metal and nitrogen cycling in marine oxygen minimum zones.
Glass, Jennifer B; Kretz, Cecilia B; Ganesh, Sangita; Ranjan, Piyush; Seston, Sherry L; Buck, Kristen N; Landing, William M; Morton, Peter L; Moffett, James W; Giovannoni, Stephen J; Vergin, Kevin L; Stewart, Frank J
2015-01-01
Iron (Fe) and copper (Cu) are essential cofactors for microbial metalloenzymes, but little is known about the metalloenyzme inventory of anaerobic marine microbial communities despite their importance to the nitrogen cycle. We compared dissolved O2, NO[Formula: see text], NO[Formula: see text], Fe and Cu concentrations with nucleic acid sequences encoding Fe and Cu-binding proteins in 21 metagenomes and 9 metatranscriptomes from Eastern Tropical North and South Pacific oxygen minimum zones and 7 metagenomes from the Bermuda Atlantic Time-series Station. Dissolved Fe concentrations increased sharply at upper oxic-anoxic transition zones, with the highest Fe:Cu molar ratio (1.8) occurring at the anoxic core of the Eastern Tropical North Pacific oxygen minimum zone and matching the predicted maximum ratio based on data from diverse ocean sites. The relative abundance of genes encoding Fe-binding proteins was negatively correlated with O2, driven by significant increases in genes encoding Fe-proteins involved in dissimilatory nitrogen metabolisms under anoxia. Transcripts encoding cytochrome c oxidase, the Fe- and Cu-containing terminal reductase in aerobic respiration, were positively correlated with O2 content. A comparison of the taxonomy of genes encoding Fe- and Cu-binding vs. bulk proteins in OMZs revealed that Planctomycetes represented a higher percentage of Fe genes while Thaumarchaeota represented a higher percentage of Cu genes, particularly at oxyclines. These results are broadly consistent with higher relative abundance of genes encoding Fe-proteins in the genome of a marine planctomycete vs. higher relative abundance of genes encoding Cu-proteins in the genome of a marine thaumarchaeote. These findings highlight the importance of metalloenzymes for microbial processes in oxygen minimum zones and suggest preferential Cu use in oxic habitats with Cu > Fe vs. preferential Fe use in anoxic niches with Fe > Cu.
Brenhouse, Heather C; Montalto, Stefanie; Stellar, James R
2006-06-30
Repeated exposure to cocaine leads to behavioral sensitization, which is the augmentation of the locomotor response to a subsequent exposure to the drug. The nucleus accumbens (NAc), a major termination site of dopaminergic neurons, is believed to be involved in behavioral sensitization and studies have demonstrated that the NAc shell can be split into five zones of analysis; the vertex, arch, cone, intermediate and ventrolateral zones [Todtenkopf MS, Stellar JR. Assessment of tyrosine hydroxylase immunoreactive innervation in five subregions of the nucleus accumbens shell in rats treated with repeated cocaine. Synapse 2000;38:261-70]. Several reports show cocaine-induced c-fos expression particularly in the intermediate zone after 14, but not 2, drug-free days following repeated cocaine administration, suggesting that this region may be involved in sensitization and particularly in the later phase of expression, versus the earlier phase of sensitization. Bilateral electrolytic lesions of the intermediate zone were made in two groups of rats, which were then repeatedly exposed to cocaine (15 mg/kg, twice/day for 5 days). One group was subsequently given a single cocaine challenge injection (15 mg/kg) after 14 drug-free days, while the other group was challenged after only 2 drug-free days. Two sham surgery groups in which an electrode was lowered but no current was passed served as controls. Results show that lesioned animals as well as sham controls exhibited behavioral sensitization to the drug. However, following a 14-day drug-free period, the lesioned animals showed significant reduction in sensitization, compared to sham controls. Together these findings suggest that the intermediate zone of the NAc shell is indeed involved in the expression phase of behavioral sensitization to cocaine.
A viscoplastic shear-zone model for deep (15-50 km) slow-slip events at plate convergent margins
NASA Astrophysics Data System (ADS)
Yin, An; Xie, Zhoumin; Meng, Lingsen
2018-06-01
A key issue in understanding the physics of deep (15-50 km) slow-slip events (D-SSE) at plate convergent margins is how their initially unstable motion becomes stabilized. Here we address this issue by quantifying a rate-strengthening mechanism using a viscoplastic shear-zone model inspired by recent advances in field observations and laboratory experiments. The well-established segmentation of slip modes in the downdip direction of a subduction shear zone allows discretization of an interseismic forearc system into the (1) frontal segment bounded by an interseismically locked megathrust, (2) middle segment bounded by episodically locked and unlocked viscoplastic shear zone, and (3) interior segment that slips freely. The three segments are assumed to be linked laterally by two springs that tighten with time, and the increasing elastic stress due to spring tightening eventually leads to plastic failure and initial viscous shear. This simplification leads to seven key model parameters that dictate a wide range of mechanical behaviors of an idealized convergent margin. Specifically, the viscoplastic rheology requires the initially unstable sliding to be terminated nearly instantaneously at a characteristic velocity, which is followed by stable sliding (i.e., slow-slip). The characteristic velocity, which is on the order of <10-7 m/s for the convergent margins examined in this study, depends on the (1) effective coefficient of friction, (2) thickness, (3) depth, and (4) viscosity of the viscoplastic shear zone. As viscosity decreases exponentially with temperature, our model predicts faster slow-slip rates, shorter slow-slip durations, more frequent slow-slip occurrences, and larger slow-slip magnitudes at warmer convergent margins.
Prevot, V; Dutoit, S; Croix, D; Tramu, G; Beauvillain, J C
1998-05-01
The ultrastructural appearance of gonadotropin releasing hormone-immunoreactive elements was studied in the external zone of the median eminence of adult female Wistar rats. On the one hand, the purpose of the study was to determine the distribution of gonadotropin releasing hormone terminals towards the parenchymatous basal lamina at the level of hypothalamo-hypophyseal portal vessels, throughout the estrous cycle. On the other hand, we have semi-quantified the gonadotropin releasing hormone content in nerve terminals or preterminals during this physiological condition. A morphometric study was coupled to a colloidal 15 mn gold postembedding immunocytochemistry procedure. Animals were killed at 09.00 on diestrus II, 0.900, 10.00, 13.00, 17.00 and 18.00 on proestrus and 09.00 on estrus (n = 4-8 rats/group). A preliminary light microscopic study was carried out to identify an antero-posterior part of median eminence strongly immunostained by anti-gonadotropin releasing hormone antibodies but which was, in addition, easily spotted. This last condition was necessary to make a good comparison between each animal. Contacts between gonadotropin releasing hormone nerve terminals and the basal lamina were observed only the day of proestrus. Such contacts, however, were rare and in the great majority of cases, gonadotropin releasing hormone terminals are separated from basal lamina by tanycytic end feet. The morphometric analysis showed no significant variation in average distance between gonadotropin releasing hormone terminals and capillaries throughout the estrous cycle. Consequently, it did not appear that a large neuroglial plasticity exists during the estrous cycle. However, the observation of contacts only on proestrus together with some ultrastructural images evoke the possibility of a slight plasticity. The semi-quantitative results show that the content of gonadotropin releasing hormone in the nerve endings presented two peaks on proestrus: one at 09.00 (23 +/- 5 particles/micrograms2, P < 0.03) before the onset of luteinizing hormone surge, and the second at 18.00 (16 +/- 2 particles/micrograms2, P < 0.01) concomitantly with the luteinizing hormone surge, when compared to baseline values on proestrus 10.00 (8 +/- particles/micrograms2).
Neff, Hector; Bigney, Scott J; Sakai, Sachiko; Burger, Paul R; Garfin, Timothy; George, Richard G; Culleton, Brendan J; Kennett, Douglas J
2016-01-01
Archaeological sediments from mounds within the mangrove zone of far-southern Pacific coastal Chiapas, Mexico, are characterized in order to test the hypothesis that specialized pyro-technological activities of the region's prehistoric inhabitants (salt and ceramic production) created the accumulations visible today. Fourier transform infrared spectroscopy (FT-IR) is used to characterize sediment mineralogy, while portable X-ray fluorescence (pXRF) is used to determine elemental concentrations. Elemental characterization of natural sediments by both instrumental neutron activation analysis (INAA) and pXRF also contribute to understanding of processes that created the archaeological deposits. Radiocarbon dates combined with typological analysis of ceramics indicate that pyro-industrial activity in the mangrove zone peaked during the Late Formative and Terminal Formative periods, when population and monumental activity on the coastal plain and piedmont were also at their peaks. © The Author(s) 2015.
Effect of Root-Zone Moisture Variations on Growth of Lettuce and Pea Plants
NASA Astrophysics Data System (ADS)
Ilieva, Iliana; Ivanova, Tania
2008-06-01
Variations in substrate moisture lead to changes in water and oxygen availability to plant roots. Ground experiments were carried out in the laboratory prototype of SVET-2 Space Greenhouse to study the effect of variation of root-zone moisture conditions on growth of lettuce and pea plants. The effect of transient increase (for 1 day) and drastic increase (waterlogging for 10 days) of substrate moisture was studied with 16-day old pea and 21-day old lettuce plants respectively. Pea height and fresh biomass accumulation were not affected by transient substrate moisture increase. Net photosynthetic rate (Pn) of pea plants showed fast response to substrate moisture variation, while chlorophyll content did not change. Drastic change of substrate moisture suppressed lettuce Pn, chlorophyll biosynthesis and plant growth. These parameters slowly recovered after termination of waterlogging treatment but lettuce yield was greatly affected. The results showed that the most sensitive physiological parameter to substrate moisture variations is photosynthesis.
Relic magma chamber structures preserved within the Mesozoic North Atlantic crust?
McCarthy, J.; Mutter, J.C.; Morton, J.L.; Sleep, Norman H.; Thompson, G.A.
1988-01-01
The North Atlantic Transect seismic reflection data, collected southwest of Bermuda, have been reinterpreted following post-stack migration and reveal two major intracrustal reflections. The shallower of these two events, located ~1 s below the igneous basement, is a subhorizontal, undulating surface that in some places is continuous for as much as 10 km. This upper crustal reflection corresponds to the intermittently sharp contact between the sheeted dikes and the underlying isotropic gabbro. A second set of lower crustal reflections, dipping ~20??-40?? eastward, is also prominent on the migrated profile and terminates downdip against the subhorizontal reflection Moho. Their presence may be ascribed to mafic-ultramafic cumulate layers frozen into the oceanic crust at the time of formation at the paleo-spreading center. The gradual thinning in the crust approaching the fracture zones is shown to be more complex than was originally inferred. An intepretation advocating crustal thickening in this narrow zone is proposed as an alternative to the crustal-thinning model of Mutter and others. -from Authors
Presynaptic LRP4 promotes synapse number and function of excitatory CNS neurons
Mosca, Timothy J; Luginbuhl, David J; Wang, Irving E; Luo, Liqun
2017-01-01
Precise coordination of synaptic connections ensures proper information flow within circuits. The activity of presynaptic organizing molecules signaling to downstream pathways is essential for such coordination, though such entities remain incompletely known. We show that LRP4, a conserved transmembrane protein known for its postsynaptic roles, functions presynaptically as an organizing molecule. In the Drosophila brain, LRP4 localizes to the nerve terminals at or near active zones. Loss of presynaptic LRP4 reduces excitatory (not inhibitory) synapse number, impairs active zone architecture, and abolishes olfactory attraction - the latter of which can be suppressed by reducing presynaptic GABAB receptors. LRP4 overexpression increases synapse number in excitatory and inhibitory neurons, suggesting an instructive role and a common downstream synapse addition pathway. Mechanistically, LRP4 functions via the conserved kinase SRPK79D to ensure normal synapse number and behavior. This highlights a presynaptic function for LRP4, enabling deeper understanding of how synapse organization is coordinated. DOI: http://dx.doi.org/10.7554/eLife.27347.001 PMID:28606304
NASA Astrophysics Data System (ADS)
Leamon, R. J.; McIntosh, S. W.
2017-12-01
Establishing a solid physical connection between solar and tropospheric variability has posed a considerable challenge across the spectrum of Earth-system science. Over the past few years a new picture to describe solar variability has developed, based on observing, understanding and tracing the progression, interaction and intrinsic variability of the magnetized activity bands that belong to the Sun's 22-year magnetic activity cycle. The intra- and extra-hemispheric interaction of these magnetic bands appear to explain the occurrence of decadal scale variability that primarily manifests itself in the sunspot cycle. However, on timescales of ten months or so, those bands posses their own internal variability with an amplitude of the same order of magnitude as the decadal scale. The latter have been tied to the existence of magnetized Rossby waves in the solar convection zone that result in surges of magnetic flux emergence that correspondingly modulate our star's radiative and particulate output. One of the most important events in the progression of these bands is their (apparent) termination at the solar equator that signals a global increase in magnetic flux emergence that becomes the new solar cycle. We look at the particulate and radiative implications of these termination points, their temporal recurrence and signature, from the Sun to the Earth, and show the correlated signature of solar cycle termination events and major oceanic oscillations that extend back many decades. A combined one-two punch of reduced particulate forcing and increased radiative forcing that result from the termination of one solar cycle and rapid blossoming of another correlates strongly with a shift from El Niño to La Niña conditions in the Pacific Ocean. This shift does not occur at solar minima, nor solar maxima, but at a particular, non-periodic, time in between. The failure to identify these termination points, and their relative irregularity, have inhibited a correlation to be observed and physical processes to be studied. This result potentially opens the door to a broader understanding of solar variability on our planet and its weather. Ongoing tracking of solar magnetic band migration indicates that Cycle 24 will terminate in the 2020 timeframe and thus we may expect to see an attendant shift to La Niña conditions at that time.
On the theory of the Frankl problem for equations of mixed type
NASA Astrophysics Data System (ADS)
Sabitov, K. B.
2017-02-01
In 1956 Frankl, while studying subsonic flows past a profile with a supersonic zone terminating with a normal compression shock, arrived at a new mathematical problem for the Chaplygin equation with a non-local boundary condition. In this article we give a survey of classical and recent papers dedicated to this problem. We present theorems on the existence and uniqueness of the solution of the Frankl problem, study the spectral problem for the Lavrent'ev-Bitsadze operator, show applications of these results to the construction of a solution with the aid of a series, and state some unsolved problems.
NASA Astrophysics Data System (ADS)
Tang, Changyan; Yang, Huan; Pancost, Richard D.; Griffiths, Michael L.; Xiao, Guoqiao; Dang, Xinyue; Xie, Shucheng
2017-12-01
Understanding the origin and evolutionary history of drought events is of great significance, providing critical insight into future hydrological conditions under the changing climate. Due to the scarcity of drought proxies from northern China, the occurrence and underlying mechanisms of the drought events remains enigmatic on longer timescales. Here we utilize microbial lipid proxies to reconstruct significant drought events over the last four ice age terminations in the southernmost section (Weinan section) of the Chinese Loess Plateau. The abundance of archaeal isoprenoid GDGTs (glycerol dialkyl glycerol tetraethers) relative to bacterial branched GDGTs, measured by Ri/b and BIT indices, is diagnostic of enhanced drought conditions. The Ri/b (and BIT) indices are stable and low (high) throughout most of the loess section spanning the last 350 thousand years, but they do exhibit sharp transient peaks (valleys) during the intervals associated with the four ice age terminations, and especially Terminations II and IV. These enhanced drought events are, non-intuitively, associated with a significant decrease in the relative abundance of C4 plants, inferred by a decrease in the carbon isotope composition of bulk organic matter. Although the microbial records show some consistency with the Weinan grain size profiles, indicative of Eastern Asian winter monsoon variability, they also show some apparent difference. In fact, some features of the microbial records exhibit strong similarities with marine sediment planktonic foraminiferal δ13C records from the western Pacific warm pool, which reflect ENSO-like changes during glacial terminations. Therefore, enhanced droughts immediately before the interglacial warming in northern China could be explained, at least in part, by teleconnections in tropical ocean-atmosphere circulation via shifts in the Intertropical Convergence Zone (ITCZ) and associated Jet Stream over the Asian continent. According to our microbial biomarker data, these enhanced megadroughts are apparently different, both in terms of severity and causal mechanism, from the more commonly discussed dry conditions observed during glacial periods.
NASA Astrophysics Data System (ADS)
Comeau, M. J.; Becken, M.; Kaeufl, J.; Kuvshinov, A. V.; Kamm, J.; Grayver, A.; Demberel, S.; Usnikh, S. U.; Batmagnai, E.; Tserendug, S.
2017-12-01
The Hangai Dome in central Mongolia is characterized by intraplate volcanism on a high-elevation intra-continental plateau. Volcanism dates from the Oligocene to the Holocene and is thought to be coincident with the onset of the uplift of the Hangai Dome, indicating that the processes may be linked. However, the processes and driving mechanisms responsible for creating this region remain largely unexplained, due in part to a lack of high-resolution geophysical data over the area. An extensive magnetotelluric (MT) data set was collected over the Hangai Dome in 2016 and 2017, with broadband data (0.002 - 5,000 s) collected at a total of 294 sites. This data set consists of a large array ( 50 km site spacing) and several long ( 600 km) and dense ( 5 km site spacing) profiles that cross the uplifted Hangai Dome. Additionally, they cross the bounding faults of the Hangai block, the Bulnay fault in the north and the Bogd fault of the Gobi-Altai in the south, which have had several M>8 earthquakes in the past century. These MT data have been used to generate electrical resistivity models of the crust and upper mantle in this region. Anomalous, low resistivity ( 30 ohm-m) zones in the lower crust ( 25 - 50 km depth) are spatially associated with the surface expressions of volcanism and modern-day hydrothermal activity. These zones indicate the presence of local accumulations of fluids below the brittle-ductile transition zone. Interestingly, this feature terminates sharply at the South Hangai Fault Zone. Furthermore, lower resistivity pathways in the upper crust (0 - 25 km depth) connect the deeper features to the surface. This is prominently observed below the Hangai's youngest volcanic zones of Tariat/Khorgo and Chuluut, as well as the hot spring area of Tsenkher, near Tsetserleg. Additionally, an electrical signature can be associated with known fault zones and mineralized zones (such as the Bayankhongor mineral belt). An anomalous low-resistivity zone in the upper mantle ( 70 - 100 km) directly below the Hangai Dome can be explained by the presence of a small amount of partial melt. This zone likely represents the region of melt generation for intraplate volcanism and gives evidence for a small-scale (<100 km) asthenospheric upwelling, which contributes to intraplate deformation.
NASA Astrophysics Data System (ADS)
Rowlett, Hugh; Forsyth, Donald W.
1984-07-01
New air gun reflection profiles, 3.5-kHz reflection profiles, and microearthquake data recorded by an array of ocean bottom seismographs form the basis for this study of the transition from a spreading center to a major transform fault. Disturbances of the thick, normally flat-lying, turbidite deposits provide indications of recent vertical motions. At the western intersection of the fracture zone with the median valley there is a depression in the sediments that represents the southerly extension of the median valley into the fracture zone valley. The depression is terminated abruptly on the south by the active transform fault, which acts as a locus for vertical as well as horizontal displacement. Flat-lying, undisturbed sediments terminate abruptly at the fault. The western boundary of the depression is much broader and is characterized by a series of slumplike steps. To the west, there is little or no evidence for uplift or tilting of sediments which might indicate vertical recovery of the crust as it spreads away from the depression. This suggests that uplift and recovery out of the depression is episodic in nature and has been inactive over the last million years along the western boundary. To the east there is clear evidence of uplift and tilting of sedimentary layers. A basement ridge emerging from the sediments is currently being uplifted and rotated in a manner analogous to processes responsible for the creation and cancellation of median valley relief. The transition between the spreading center and the transform fault appears to take place within 1-2 km. The width of the transform fault just east of the depression is less than a kilometer. Microearthquakes were located and displayed by new methods that directly account for nonlinearities associated with small arrays. Microearthquakes located by three or more ocean bottom seismometers show that the greatest seismic activity occurs along the eastern walls of the median valley, at the basement ridge, in the eastern portion of the depression and in the crestal mountains. Very little activity is associated with the western edge of the transform depression and the trace of the transform fault.
Iron snow in the Martian core?
NASA Astrophysics Data System (ADS)
Davies, Christopher J.; Pommier, Anne
2018-01-01
The decline of Mars' global magnetic field some 3.8-4.1 billion years ago is thought to reflect the demise of the dynamo that operated in its liquid core. The dynamo was probably powered by planetary cooling and so its termination is intimately tied to the thermochemical evolution and present-day physical state of the Martian core. Bottom-up growth of a solid inner core, the crystallization regime for Earth's core, has been found to produce a long-lived dynamo leading to the suggestion that the Martian core remains entirely liquid to this day. Motivated by the experimentally-determined increase in the Fe-S liquidus temperature with decreasing pressure at Martian core conditions, we investigate whether Mars' core could crystallize from the top down. We focus on the "iron snow" regime, where newly-formed solid consists of pure Fe and is therefore heavier than the liquid. We derive global energy and entropy equations that describe the long-timescale thermal and magnetic history of the core from a general theory for two-phase, two-component liquid mixtures, assuming that the snow zone is in phase equilibrium and that all solid falls out of the layer and remelts at each timestep. Formation of snow zones occurs for a wide range of interior and thermal properties and depends critically on the initial sulfur concentration, ξ0. Release of gravitational energy and latent heat during growth of the snow zone do not generate sufficient entropy to restart the dynamo unless the snow zone occupies at least 400 km of the core. Snow zones can be 1.5-2 Gyrs old, though thermal stratification of the uppermost core, not included in our model, likely delays onset. Models that match the available magnetic and geodetic constraints have ξ0 ≈ 10% and snow zones that occupy approximately the top 100 km of the present-day Martian core.
Characterizing the Effect of Laser Power on Laser Metal Deposited Titanium Alloy and Boron Carbide
NASA Astrophysics Data System (ADS)
Akinlabi, E. T.; Erinosho, M. F.
2017-11-01
Titanium alloy has gained acceptance in the aerospace, marine, chemical, and other related industries due to its excellent combination of mechanical and corrosion properties. In order to augment its properties, a hard ceramic, boron carbide has been laser cladded with it at varying laser powers between 0.8 and 2.4 kW. This paper presents the effect of laser power on the laser deposited Ti6Al4V-B4C composites through the evolving microstructures and microhardness. The microstructures of the composites exhibit the formation of α-Ti phase and β-Ti phase and were elongated towards the heat affected zone. These phases were terminated at the fusion zone and globular microstructures were found growing epitaxially just immediately after the fusion zone. Good bondings were formed in all the deposited composites. Sample A1 deposited at a laser power of 0.8 kW and scanning speed of 1 m/min exhibits the highest hardness of HV 432 ± 27, while sample A4 deposited at a laser power of 2.0 kW and scanning speed of 1 m/min displays the lowest hardness of HV 360 ± 18. From the hardness results obtained, ceramic B4C has improved the mechanical properties of the primary alloy.
NASA Astrophysics Data System (ADS)
Schuba, C. Nur; Gray, Gary G.; Morgan, Julia K.; Sawyer, Dale S.; Shillington, Donna J.; Reston, Tim J.; Bull, Jonathan M.; Jordan, Brian E.
2018-06-01
A new 3-D seismic reflection volume over the Galicia margin continent-ocean transition zone provides an unprecedented view of the prominent S-reflector detachment fault that underlies the outer part of the margin. This volume images the fault's structure from breakaway to termination. The filtered time-structure map of the S-reflector shows coherent corrugations parallel to the expected paleo-extension directions with an average azimuth of 107°. These corrugations maintain their orientations, wavelengths and amplitudes where overlying faults sole into the S-reflector, suggesting that the parts of the detachment fault containing multiple crustal blocks may have slipped as discrete units during its late stages. Another interface above the S-reflector, here named S‧, is identified and interpreted as the upper boundary of the fault zone associated with the detachment fault. This layer, named the S-interval, thickens by tens of meters from SE to NW in the direction of transport. Localized thick accumulations also occur near overlying fault intersections, suggesting either non-uniform fault rock production, or redistribution of fault rock during slip. These observations have important implications for understanding how detachment faults form and evolve over time. 3-D seismic reflection imaging has enabled unique insights into fault slip history, fault rock production and redistribution.
Willingham, C. Richard; Rietman, Jan D.; Heck, Ronald G.; Lettis, William R.
2013-01-01
The Hosgri Fault Zone trends subparallel to the south-central California coast for 110 km from north of Point Estero to south of Purisima Point and forms the eastern margin of the present offshore Santa Maria Basin. Knowledge of the attributes of the Hosgri Fault Zone is important for petroleum development, seismic engineering, and environmental planning in the region. Because it lies offshore along its entire reach, our characterizations of the Hosgri Fault Zone and adjacent structures are primarily based on the analysis of over 10,000 km of common-depth-point marine seismic reflection data collected from a 5,000-km2 area of the central and eastern parts of the offshore Santa Maria Basin. We describe and illustrate the along-strike and downdip geometry of the Hosgri Fault Zone over its entire length and provide examples of interpreted seismic reflection records and a map of the structural trends of the fault zone and adjacent structures in the eastern offshore Santa Maria Basin. The seismic data are integrated with offshore well and seafloor geologic data to describe the age and seismic appearance of offshore geologic units and marker horizons. We develop a basin-wide seismic velocity model for depth conversions and map three major unconformities along the eastern offshore Santa Maria Basin. Accompanying plates include maps that are also presented as figures in the report. Appendix A provides microfossil data from selected wells and appendix B includes uninterpreted copies of the annotated seismic record sections illustrated in the chapter. Features of the Hosgri Fault Zone documented in this investigation are suggestive of both lateral and reverse slip. Characteristics indicative of lateral slip include (1) the linear to curvilinear character of the mapped trace of the fault zone, (2) changes in structural trend along and across the fault zone that diminish in magnitude toward the ends of the fault zone, (3) localized compressional and extensional structures characteristic of constraining and releasing bends and stepovers, (4) changes in the sense and magnitude of vertical separation along strike within the fault zone, and (5) changes in downdip geometry between the major traces and segments of the fault zone. Characteristics indicative of reverse slip include (1) reverse fault geometries that occur across major strands of the fault zone and (2) fault-bend folds and localized thrust faults that occur along the northern and southern reaches of the fault. Analyses of high-resolution, subbottom profiler and side-scan sonar records indicate localized Holocene activity along most of the extent of the fault zone. Collectively, these features are the basis of our characterization of the Hosgri Fault Zone as an active, 110-km-long, convergent right-oblique slip (transpressional) fault with identified northern and southern terminations. This interpretation is consistent with recently published analyses of onshore geologic data, regional tectonic kinematic models, and instrumental seismicity.
Transfer zones in listric normal fault systems
NASA Astrophysics Data System (ADS)
Bose, Shamik
Listric normal faults are common in passive margin settings where sedimentary units are detached above weaker lithological units, such as evaporites or are driven by basal structural and stratigraphic discontinuities. The geometries and styles of faulting vary with the types of detachment and form landward and basinward dipping fault systems. Complex transfer zones therefore develop along the terminations of adjacent faults where deformation is accommodated by secondary faults, often below seismic resolution. The rollover geometry and secondary faults within the hanging wall of the major faults also vary with the styles of faulting and contribute to the complexity of the transfer zones. This study tries to understand the controlling factors for the formation of the different styles of listric normal faults and the different transfer zones formed within them, by using analog clay experimental models. Detailed analyses with respect to fault orientation, density and connectivity have been performed on the experiments in order to gather insights on the structural controls and the resulting geometries. A new high resolution 3D laser scanning technology has been introduced to scan the surfaces of the clay experiments for accurate measurements and 3D visualizations. Numerous examples from the Gulf of Mexico have been included to demonstrate and geometrically compare the observations in experiments and real structures. A salt cored convergent transfer zone from the South Timbalier Block 54, offshore Louisiana has been analyzed in detail to understand the evolutionary history of the region, which helps in deciphering the kinematic growth of similar structures in the Gulf of Mexico. The dissertation is divided into three chapters, written in a journal article format, that deal with three different aspects in understanding the listric normal fault systems and the transfer zones so formed. The first chapter involves clay experimental models to understand the fault patterns in divergent and convergent transfer zones. Flat base plate setups have been used to build different configurations that would lead to approaching, normal offset and overlapping faults geometries. The results have been analyzed with respect to fault orientation, density, connectivity and 3D geometry from photographs taken from the three free surfaces and laser scans of the top surface of the clay cake respectively. The second chapter looks into the 3D structural analysis of the South Timbalier Block 54, offshore Louisiana in the Gulf of Mexico with the help of a 3D seismic dataset and associated well tops and velocity data donated by ExxonMobil Corporation. This study involves seismic interpretation techniques, velocity modeling, cross section restoration of a series of seismic lines and 3D subsurface modeling using depth converted seismic horizons, well tops and balanced cross sections. The third chapter deals with the clay experiments of listric normal fault systems and tries to understand the controls on geometries of fault systems with and without a ductile substrate. Sloping flat base plate setups have been used and silicone fluid underlain below the clay cake has been considered as an analog for salt. The experimental configurations have been varied with respect to three factors viz. the direction of slope with respect to extension, the termination of silicone polymer with respect to the basal discontinuities and overlap of the base plates. The analyses for the experiments have again been performed from photographs and 3D laser scans of the clay surface.
How the optic nerve allocates space, energy capacity, and information
Perge, Janos A.; Koch, Kristin; Miller, Robert; Sterling, Peter; Balasubramanian, Vijay
2009-01-01
Fiber tracts should use space and energy efficiently because both resources constrain neural computation. We found for a myelinated tract (optic nerve) that astrocytes use nearly 30% of the space and more than 70% of the mitochondria, establishing the significance of astrocytes for the brain’s space and energy budgets. Axons are mostly thin with a skewed distribution peaking at 0.7µm, near the lower limit set by channel noise. This distribution is matched closely by the distribution of mean firing rates measured under naturalistic conditions, suggesting that firing rate increases proportionally with axon diameter. In axons thicker than 0.7µm mitochondria occupy a constant fraction of axonal volume -- thus, mitochondrial volumes rise as the diameter squared. These results imply a law of diminishing returns: twice the information rate requires more than twice the space and energy capacity. We conclude that the optic nerve conserves space and energy by sending most information at low rates over fine axons with small terminal arbors, and sending some information at higher rates over thicker axons with larger terminal arbors – but only where more bits/s are needed for a specific purpose. Thicker axons seem to be needed, not for their greater conduction velocity (nor other intrinsic electrophysiological purpose), but instead to support larger terminal arbors and more active zones that transfer information synaptically at higher rates. PMID:19535603
NASA Astrophysics Data System (ADS)
Haghdadi, N.; Cizek, P.; Hodgson, P. D.; Tari, V.; Rohrer, G. S.; Beladi, H.
2018-05-01
The crystallography of interfaces in a duplex stainless steel having an equiaxed microstructure produced through the ferrite to austenite diffusive phase transformation has been studied. The five-parameter interface character distribution revealed a high anisotropy in habit planes for the austenite-ferrite and austenite-austenite interfaces for different lattice misorientations. The austenite and ferrite habit planes largely terminated on (1 1 1) and (1 1 0) planes, respectively, for the austenite-ferrite interfaces associated with Kurdjumov-Sachs (K-S) and Nishiyama-Wasserman (N-W) orientation relationships. This was mostly attributed to the crystallographic preference associated with the phase transformation. For the austenite-ferrite interfaces with orientation relationships which are neither K-S nor N-W, both austenite and ferrite habit planes had (1 1 1) orientations. Σ3 twin boundaries comprised the majority of austenite-austenite interfaces, mostly showing a pure twist character and terminating on (1 1 1) planes due to the minimum energy configuration. The second highest populated austenite-austenite boundary was Σ9, which tended to have grain boundary planes in the tilt zone due to the geometrical constraints. Furthermore, the intervariant crystallographic plane distribution associated with the K-S orientation relationship displayed a general tendency for the austenite habit planes to terminate with the (1 1 1) orientation, mainly due to the crystallographic preference associated with the phase transformation.
NASA Astrophysics Data System (ADS)
McGrath, Daniel J.
Understanding ice shelf structure and processes is paramount to future predictions of sea level rise, as nearly 75% of the ice flux from the Antarctic Ice Sheet (AIS) passes through these gates. The breakup of an ice shelf removes the longitudinal back stress acting on the grounded inland ice and leads to flow acceleration, dynamic thinning and frontal retreat, processes that can be sustained for more than a decade. Increased ice discharge to the ocean contributes to global sea level rise. This dissertation investigates basal crevasses and suture zones, two key structural components of ice shelves, in order to understand how the structure of an ice shelf influences its stability in a warming climate. Ground penetrating radar, high-resolution satellite imagery and a variety of modeling approaches are utilized to assess these features on the Larsen C Ice Shelf but in a manner that considers their influence on ice shelf stability around the AIS. Basal crevasses are large-scale (~66% of ice thickness and ten's of kms in length) and abundant features that are significant structural weaknesses. The viscoplastic deformation of the ice shelf in response to the perturbed hydrostatic balance leads to the formation of both surface depressions and crevasses, hence weakening the ice shelf further. Basal crevasses increase the local ice-ocean interface by ~30%, thereby increasing basal roughness and altering ice-ocean interactions. Ice-shelf fractures frequently terminate where they encounter suture zones, regions of material heterogeneity that form at the lateral bounds of meteoric inflows to ice shelves. The termination of a 25 km-long rift in the Churchill Peninsula suture zone is investigated and found to contain ~60 m of accreted marine ice. Steady-state basal melting/freezing rates are determined for the ice shelf and applied to a flowline model to examine the along-flow evolution of ice shelf structure. The thickening surface wedge of locally accumulated meteoric ice, which likely has limited lateral variation in its mechanical properties, accounts for ~60% of the total ice thickness near the calving front. This suggests that the material heterogeneities present in the lower ~40% of the ice column are responsible for resisting fracture propagation and thereby delaying tabular calving events. This represents a highly sensitive aspect of ice-shelf stability, as changes in the oceanic forcing may lead to the loss of this heterogeneity.
NASA Astrophysics Data System (ADS)
Katori, T.; Kobayashi, K.
2015-12-01
The central Japan is one of the most concentrated area of active faults (Quaternary fault). These are roughly classified into two orthogonally-oriented fault sets of NE-SW and NW-SE strikes. The study area is located in Gifu prefecture, central Japan. In there, the basement rocks are composed mainly of Triassic-Jurassic accretionary prism (Mino belt), Cretaceous Nohi Rhyolite and Cretaceous granitic rocks. Miocene Mizunami G. and Pliocene-Pleistocene Toki Sand and Gravel F. unconformably cover the basement rocks. The Byobuyama fault, 32 km in length, is NE-SW strike and displaces perpendicularly the Toki Sand and Gravel F. by 500 m. The northeastern terminal of the fault has contact with the southern terminal of the Atera fault of NW-SE strike and offset their displacements each other. It is clear that the activity of the Byobuyama fault plays a role of the development of the complicated fault geometry system in the central Japan. In this study, we performed a broad-based investigation along the Byobuyama fault and collected samples. Actually, we observed 400 faults and analyzed 200 fault rocks. Based on these results, we obtained the following new opinion. 1. The Byobuyama fault has experienced following activities that can be divided to 3 stages at least under different stress field. 1) Movement with the sinisterly sense (preserved in cataclasite zone). 2) Dextral movement (preserved in fault gouge zone). 3) Reverse fault movement (due to the aggressive rise of mountains). In addition, the change from Stage 2 to Stage 3 is a continuous. 2. There is a relationship between the distance from the trace of the Byobuyama fault and the combination of alteration minerals included in the fault rocks. 3. In the central part of the Byobuyama fault (CPBF), fault plane trend and combination of alteration minerals shows specific features. The continuous change is considered to mean the presence of factors that interfere with the dextral movement of the Byobuyama fault. What is considered as one of the factors is the effect of the fault zone adjacent, especially the Atera fault. CPBF is located just southeast extension of the Akou fault, NW-SE strike. We think that this extension reaches up to CPBF. Based on the above, we make a presentation about interaction of two faults from the point of view of kinematic vicissitudes and alteration process.
NASA Astrophysics Data System (ADS)
Wilde-Piórko, Monika; Świeczak, Marzena; Grad, Marek; Majdański, Mariusz
2010-01-01
The structure and evolution of the Trans-European Suture zone (TESZ), contact between Precambrian Europe to the northeast and Phanerozoic terranes to the southwest is one of the main tectonic questions in Europe. The knowledge of the crustal structure, lithosphere-asthenosphere boundary and mantle transition zone between two seismic discontinuities at depths "410" and "660" km, is one of the most important issues to understand the Earth's dynamics. To create a mantle model of the TESZ and surroundings we used different seismic data collected along the 950 km long POLONAISE'97 profile P4. Previous results of 2-D ray-tracing and P-wave travel time modelling and new results of P-wave travel time residuals methods and receiver function sections provide facts about the seismic structure from the surface down to 900 km depth. In the TESZ a large basin, about 125 km wide, is filled with sedimentary strata (Vp < 6.0 km s - 1 ) to about 20 km depth. This basin is asymmetric with its northeast margin being most abrupt. The crystalline crust under this basin is only about 20 km thick today indicating that the lithosphere of Baltica was either thinned drastically or terminated along the northeast margin of the basin. The East European craton (EEC) has a ~ 45 km thick three-layered crust. The crust of the accreted terranes to the southwest is relatively thin (~ 30 km) and similar to that found in other non-cratonal areas of Western Europe. The lower crust is relatively fast (Vp > 7.0 km s - 1 ) along most of the P4 profile. However, lower values to the southwest may indicate the termination of Baltica. High velocity (~ 8.35 km s - 1 ) uppermost mantle lies beneath the Avalonia/Variscan terranes, and may be due to rifting and/or subduction. The seismic lithosphere thickness for the EEC is about 200 km, while it is only 90 km in the Palaeozoic platform (PP). The mantle transition zone is shallower and about 30 km thicker under the EEC, which could be due to thermal conditions (lower temperature) and/or the presence of water and FeO. The result of this paper is a new compiled and integrated seismic velocity model, available in digital form down to 900 km depth ( http://www.igf.fuw.edu.pl/p4-mantle), which can be used as a preliminary model of the crust and upper mantle in the TESZ area in Central Europe.
NASA Astrophysics Data System (ADS)
Bistacchi, A.; Mittempergher, S.; Di Toro, G.; Smith, S. A. F.; Garofalo, P. S.
2016-12-01
The Gole Larghe Fault Zone (GLFZ) was exhumed from 8 km depth, where it was characterized by seismic activity (pseudotachylytes) and hydrous fluid flow (alteration halos and precipitation of hydrothermal minerals in veins and cataclasites). Thanks to glacier-polished outcrops exposing the 400 m-thick fault zone over a continuous area > 1.5 km2, the fault zone architecture has been quantitatively described with an unprecedented detail, providing a rich dataset to generate 3D Discrete Fracture Network (DFN) models and simulate the fault zone hydraulic properties. The fault and fracture network has been characterized combining > 2 km of scanlines and semi-automatic mapping of faults and fractures on several photogrammetric 3D Digital Outcrop Models (3D DOMs). This allowed obtaining robust probability density functions for parameters of fault and fracture sets: orientation, fracture intensity and density, spacing, persistency, length, thickness/aperture, termination. The spatial distribution of fractures (random, clustered, anticlustered…) has been characterized with geostatistics. Evidences of fluid/rock interaction (alteration halos, hydrothermal veins, etc.) have been mapped on the same outcrops, revealing sectors of the fault zone strongly impacted, vs. completely unaffected, by fluid/rock interaction, separated by convolute infiltration fronts. Field and microstructural evidence revealed that higher permeability was obtained in the syn- to early post-seismic period, when fractures were (re)opened by off-fault deformation. We have developed a parametric hydraulic model of the GLFZ and calibrated it, varying the fraction of faults/fractures that were open in the post-seismic, with the goal of obtaining realistic fluid flow and permeability values, and a flow pattern consistent with the observed alteration/mineralization pattern. The fraction of open fractures is very close to the percolation threshold of the DFN, and the permeability tensor is strongly anisotropic, resulting in a marked channelling of fluid flow in the inner part of the fault zone. Amongst possible seismological applications of our study, we will discuss the possibility to evaluate the coseismic fracture intensity due to off-fault damage, a fundamental mechanical parameter in the energy balance of earthquakes.
Rapid Grain Size Reduction in the Upper Mantle at a Plate Boundary
NASA Astrophysics Data System (ADS)
Kidder, S. B.; Scott, J.; Prior, D. J.; Lubicich, E. J.
2017-12-01
A few spinel peridotite xenoliths found near the Alpine Fault, New Zealand, exhibit a mylonitic texture and, locally, an extremely fine 30 micron grain size. The harzburgite xenoliths were emplaced in a 200 km-long elongate dike zone interpreted as a gigantic tension fracture or Reidel shear associated with Alpine Fault initiation 25 Ma. The presence of thin ( 1 mm) ultramylonite zones with px-ol phase mixing and fine grain sizes, minimal crustal-scale strain associated with the dike swarm, and the absence of mylonites at four of the five xenolith localities associated with the dike swarm indicate that upper mantle deformation was highly localized. Strings of small, recrystallized grains (planes in 3D) are found in the interiors of olivine porphyroclasts. In some cases, bands 1-2 grains thick are traced from the edges of olivine grains and terminate in their interiors. Thicker zones of recrystallized grains are also observed crossing olivine porphyroclasts without apparent offset of the unrecrystallized remnants of the porphyroclasts. We suggest a brittle-plastic origin for these features since the traditional recrystallization mechanisms associated with dislocation creep require much more strain than occurred within these porphyroclasts. Analogous microstructures in quartz and feldspar in mid-crust deformation zones are attributed to brittle-plastic processes. We hypothesize that such fine-grained zones were the precursors of the observed, higher-strain ultramylonite zones. Given the size of the new grains preserved in the porphyroclasts ( 100 micron) and a moho temperature > 650°C, grain growth calculations indicate that the observed brittle-plastic deformation occurred <10,000 yrs. prior to eruption. It is likely then that either brittle-plastic deformation was coeval with the ductile shearing occurring in the ultramylonite bands, or possibly, if deformation can be separated into brittle-plastic (early) and ductile (later) phases, that the entire localization process was very rapid (<10,000 yrs). In either case we interpret that semi-brittle deformation was a key process responsible for rapid localization in this initiating plate-scale mantle shear zone.
NASA Astrophysics Data System (ADS)
Yilmaz, Tim I.; Blenkinsop, Tom; Duschl, Florian; Kruhl, Jörn H.
2015-04-01
Silicified fault rocks typically show structures resulting from various stages of fragmentation and quartz crystallization. Both processes interact episodically and result in complex structures on various scales, which require a wide spectrum of analysis tools. Based on field and microstructural data, the spatial-temporal connection between deformation, quartz crystallization and fluid and material flow along the Rusey fault zone was investigated. The fault can be examined in detail in three dimensions on the north Cornwall coast, UK. It occurs within Carboniferous sandstones, siltstones, mudstones and slates of the Culm basin, and is likely to have had a long history. The fault rocks described here formed during the younger events, possibly due to Tertiary strike-slip reactivation. Frequent fragmentation, flow and crystallization events and their interaction led to various generations of complex-structured quartz units, among them quartz-mantled and partly silicified wall-rock fragments, microcrystalline quartz masses of different compositions and structures, and quartz vein patterns of various ages. Lobate boundaries of quartz masses indicate viscous flow. Fragments are separated by quartz infill, which contains cm-sized open pores, in which quartz crystals have pyramidal terminations. Based on frequent occurrence of feathery textures and the infill geometry, quartz crystallization from chalcedony appears likely, and an origin from silica gel is discussed. Fragmentation structures are generally fractal. This allows differentiation between various processes, such as corrosive wear, wear abrasion and hydraulic brecciation. Material transport along the brittle shear zone, and displacement of the wall-rocks, were at least partly governed by flow of mobile fluid-quartz-particle suspensions. The complex meso- to microstructures were generated by repeated processes of fragmentation, quartz precipitation and grain growth. In general, the brittle Rusey fault zone represents a zone of multiple fragmentation, fluid flow, crystallization and quartz dissolution and precipitation, and is regarded as key example of large-scale cyclic interaction of these processes. The geological evidence of interactions between processes implies that feedbacks and highly non-linear mechanical behaviour generated the complex meso- and microstructures. The fault zone rheology may also therefore have been complex.
NASA Astrophysics Data System (ADS)
Martin-Short, R.; Allen, R. M.; Porritt, R.
2017-12-01
Alaska consists of a complex arrangement of terranes of various geological affinities, mostof which have been accreted to the margin of North America over the last 200Myr. Today,the southern margin of Alaska is a site of active subduction, displaying a myriad ofenigmatic tectonic features. These include transition from compressional to strike-slipdominated deformation, accretion of the over-thickened Yakutat terrane, termination ofAleutian arc magnetism and the Wrangell Volcanic Field, whose magma source remainsdebated. The ongoing deployment of Transportable Array (TA) seismometers across Alaskaprovides an unprecedented opportunity to image these features in detail and learn moreabout the tectonic history of the region. Here we present a three dimensional model ofshear wave (Vsv) velocity beneath Alaska constructed using joint inversion of phasevelocity maps derived from ambient noise and teleseismic surface wave tomography. Thismodel possesses good resolution from the upper crust to about 150km depth, thuscomplementing recent body wave models of the region, which lack resolution above 100km.In the upper crust, we are able to distinguish major sedimentary basins and the cores ofmountain belts. At mid-crustal depths, we see a sharp velocity contrast across the Denalifault, suggesting that it marks a significant step in crustal thickness. In the mantle wedgeabove the subducting Yakutat terrane we observe a high velocity anomaly that may berelated to paucity of volcanism in this region. At greater depths, we image the subductingPacific-Yakutat slab as an elongate, high velocity anomaly that terminates abruptly at 145ºW, slightly further east than suggested by the Wadati-Benioff zone alone. There is alarge, low velocity anomaly beneath the Wrangell Volcanic Field, hinting that magmatismhere may be related to mantle upwelling around the slab edge.
Impacts of Cover Crops on Water and Nutrient Dynamics in Agroecosystems
NASA Astrophysics Data System (ADS)
Williard, K.; Swanberg, S.; Schoonover, J.
2013-05-01
Intensive cropping systems of corn (Zea Mays L.) and soybeans (Glycine max) are commonly leaky systems with respect to nitrogen (N). Reactive N outputs from agroecosystems can contribute to eutrophication and hypoxic zones in downstream water bodies and greenhouse gas (N2O) emissions. Incorporating cover crops into temperate agroecosystem rotations has been promoted as a tool to increase nitrogen use efficiency and thus limit reactive N outputs to the environment. Our objective was determine how cereal rye (Secale cereal L.) and annual ryegrass (Lolium multiflorum) cover crops impact nutrient and soil water dynamics in an intensive corn and soybean cropping rotation in central Illinois. Cover crops were planted in mid to late October and terminated in early April prior to corn or soybean planting. In the spring just prior to cover crop termination, soil moisture levels were lower in the cover crop plots compared to no cover plots. This can be a concern for the subsequent crop in relatively dry years, which the Midwestern United States experienced in 2012. No cover plots had greater nutrient leaching below the rooting zone compared to cover crop areas, as expected. The cover crops were likely scavenging nutrients during the fall and early spring and should provide nutrients to the subsequent crop via decomposition and mineralization of the cover crop residue. Over the long term, cover crop systems should produce greater inputs and cycling of carbon and N, increasing the productivity of crops due to the long-term accumulation of soil organic matter. This study demonstrates that there may be short term trade-offs in reduced soil moisture levels that should be considered alongside the long term nutrient scavenging and recycling benefits of cover crops.
NASA Astrophysics Data System (ADS)
Peltier, W. Richard; Marshall, Shawn
1995-07-01
We apply a coupled energy-balance/ice-sheet climate model in an investigation of northern hemisphere ice-sheet advance and retreat over the last glacial cycle. When driven only by orbital insolation variations, the model predicts ice-sheet advances over the continents of North America and Eurasia that are in good agreement with geological reconstructions in terms of the timescale of advance and the spatial positioning of the main ice masses. The orbital forcing alone, however, is unable to induce the observed rapid ice-sheet retreat, and we conclude that additional climatic feedbacks not explicitly included in the basic model must be acting. In the analyses presented here we have parameterized a number of potentially important effects in order to test their relative influence on the process of glacial termination. These include marine instability, thermohaline circulation effects, carbon dioxide variations, and snow albedo changes caused by dust loading during periods of high atmospheric aerosol concentration. For the purpose of these analyses the temporal changes in the latter two variables were inferred from ice core records. Of these various influences, our analyses suggest that the albedo variations in the ice-sheet ablation zone caused by dust loading may represent an extremely important ablation mechanism. Using our parameterization of "dirty" snow in the ablation zone we find glacial retreat to be strongly accelerated, such that complete collapse of the otherwise stable Laurentide ice sheet ensues. The last glacial maximum configurations of the Laurentide and Fennoscandian complexes are also brought into much closer accord with the ICE-3G reconstruction of Tushingham and Peltier (1991,1992) and the ICE-4G reconstruction of Peltier (1994) when this effect is reasonably introduced.
Ito, Tetsufumi; Oliver, Douglas L.
2012-01-01
The inferior colliculus (IC) in the midbrain of the auditory system uses a unique basic circuit to organize the inputs from virtually all of the lower auditory brainstem and transmit this information to the medial geniculate body (MGB) in the thalamus. Here, we review the basic circuit of the IC, the neuronal types, the organization of their inputs and outputs. We specifically discuss the large GABAergic (LG) neurons and how they differ from the small GABAergic (SG) and the more numerous glutamatergic neurons. The somata and dendrites of LG neurons are identified by axosomatic glutamatergic synapses that are lacking in the other cell types and exclusively contain the glutamate transporter VGLUT2. Although LG neurons are most numerous in the central nucleus of the IC (ICC), an analysis of their distribution suggests that they are not specifically associated with one set of ascending inputs. The inputs to ICC may be organized into functional zones with different subsets of brainstem inputs, but each zone may contain the same three neuron types. However, the sources of VGLUT2 axosomatic terminals on the LG neuron are not known. Neurons in the dorsal cochlear nucleus, superior olivary complex, intermediate nucleus of the lateral lemniscus, and IC itself that express the gene for VGLUT2 only are the likely origin of the dense VGLUT2 axosomatic terminals on LG tectothalamic neurons. The IC is unique since LG neurons are GABAergic tectothalamic neurons in addition to the numerous glutamatergic tectothalamic neurons. SG neurons evidently target other auditory structures. The basic circuit of the IC and the LG neurons in particular, has implications for the transmission of information about sound through the midbrain to the MGB. PMID:22855671
New main reflector, subreflector and dual chamber concepts for compact range applications
NASA Technical Reports Server (NTRS)
Pistorius, C. W. I.; Burnside, W. D.
1987-01-01
A compact range is a facility used for the measurement of antenna radiation and target scattering problems. Most presently available parabolic reflectors do not produce ideal uniform plane waves in the target zone. Design improvements are suggested to reduce the amplitude taper, ripple and cross polarization errors. The ripple caused by diffractions from the reflector edges can be reduced by adding blended rolled edges and shaping the edge contour. Since the reflected edge continues smoothly from the parabola onto the rolled surface, rather than being abruptly terminated, the discontinuity in the reflected field is reduced which results in weaker diffracted fields. This is done by blending the rolled edges from the parabola into an ellipse. An algorithm which enables one to design optimum blended rolled edges was developed that is based on an analysis of the continuity of the surface radius of curvature and its derivatives across the junction. Futhermore, a concave edge contour results in a divergent diffracted ray pattern and hence less stray energy in the target zone. Design equations for three-dimensional reflectors are given. Various examples were analyzed using a new physical optics method which eliminates the effects of the false scattering centers on the incident shadow boundaries. A Gregorian subreflector system, in which both the subreflector and feed axes are tilted, results in a substantial reduction in the amplitude taper and cross polarization errors. A dual chamber configuration is proposed to eliminate the effects of diffraction from the subreflector and spillover from the feed. A computationally efficient technique, based on ray tracing and aperture integration, was developed to analyze the scattering from a lossy dielectric slab with a wedge termination.
NASA Astrophysics Data System (ADS)
Moffitt, Sarah E.; Hill, Tessa M.; Ohkushi, Kenichi; Kennett, James P.; Behl, Richard J.
2014-01-01
we present a history of deoxygenation of upper intermediate waters during the last deglaciation from Santa Barbara Basin (SBB), based on quantitative analyses of benthic foraminiferal assemblages, from a new shallow piston core above basin sill depth (MV0811-15JC, 418 m), and previously described sequences in the deeper basin (MD02-2504, 481 m and MD02-2503, 570 m). We document a 152 m depth transect of benthic foraminiferal assemblages to extract changing community structure (density, diversity, and evenness) and improve paleoenvironmental interpretation of late Quaternary vertical oscillations in the upper boundary of the oxygen minimum zone (OMZ). Close interaction between changes in open margin OMZ and that of the restricted SBB is documented using these quantitative techniques. MV0811-15JC, while being unlaminated, contains strongly hypoxic foraminiferal assemblages (including species Bolivina tumida and Nonionella stella), coeval with preserved sediment laminations in the deeper cores. Last Glacial Maximum (LGM) assemblages across this transect contained oxic fauna and high diversity. At 14.7 ka, glacial termination IA, hypoxic benthic fauna appeared across the transect, recording hypoxic waters (<0.5 ml L-1) < 300 m from the ocean surface. Bølling/Allerød (B/A) assemblages uniquely stand out in the record, exhibited by low density, diversity, and evenness, and taxonomic composition reflecting extreme and stressful hypoxia and methane-rich environments. Younger Dryas assemblages were diverse and composed of oxic fauna, similar to LGM assemblages. Termination IB initiated another deoxygenation shift, followed by OMZ-associated faunal and density patterns. This analysis strengthens the quantitative assessment of oxygen concentrations involved in deglacial OMZ change and reveals the unexpected, remarkable shallowness of OMZ influence during the B/A.
Ford, M.; Ferguson, C.C.
1985-01-01
In south-west Ireland, hydrothermally formed arsenopyrite crystals in a Devonian mudstone have responded to Variscan deformation by brittle extension fracture and fragment separation. The interfragment gaps and terminal extension zones of each crystal are infilled with fibrous quartz. Stretches within the cleavage plane have been calculated by the various methods available, most of which can be modified to incorporate terminal extension zones. The Strain Reversal Method is the most accurate currently available but still gives a minimum estimate of the overall strain. The more direct Hossain method, which gives only slightly lower estimates with this data, is more practical for field use. A strain ellipse can be estimated from each crystal rosette composed of three laths (assuming the original interlimb angles were all 60??) and, because actual rather than relative stretches are estimated, this provides a lower bound to the area increase in the plane of cleavage. Based on the average of our calculated strain ellipses this area increase is at least 114% and implies an average shortening across the cleavage of at least 53%. However, several lines of evidence suggest that the cleavage deformation was more intense and more oblate than that calculated, and we argue that a 300% area increase in the cleavage plane and 75% shortening across the cleavage are more realistic estimates of the true strain. Furthermore, the along-strike elongation indicated is at least 80%, which may be regionally significant. Estimates of orogenic contraction derived from balanced section construction should therefore take into account the possibility of a substantial strike elongation, and tectonic models that can accommodate such elongations need to be developed. ?? 1985.
Nava, Nicoletta; Chen, Fenghua; Wegener, Gregers; Popoli, Maurizio; Nyengaard, Jens Randel
2014-02-01
Communication between neurons is mediated by the release of neurotransmitter-containing vesicles from presynaptic terminals. Quantitative characterization of synaptic vesicles can be highly valuable for understanding mechanisms underlying synaptic function and plasticity. We performed a quantitative ultrastructural analysis of cortical excitatory synapses by mean of a new, efficient method, as an alternative to three-dimensional (3D) reconstruction. Based on a hierarchical sampling strategy and unequivocal identification of the region of interest, serial sections from excitatory synapses of medial prefrontal cortex (mPFC) of six Sprague-Dawley rats were acquired with a transmission electron microscope. Unbiased estimates of total 3D volume of synaptic terminals were obtained through the Cavalieri estimator, and adequate correction factors for vesicle profile number estimation were applied for final vesicle quantification. Our analysis was based on 79 excitatory synapses, nonperforated (NPSs) and perforated (PSs) subtypes. We found that total number of docked and reserve-pool vesicles in PSs significantly exceeded that in NPSs (by, respectively, 77% and 78%). These differences were found to be related to changes in size between the two subtypes (active zone area by 86%; bouton volume by 105%) rather than to postsynaptic density shape. Positive significant correlations were found between number of docked and reserve-pool vesicles, active zone area and docked vesicles, and bouton volume and reserve pool vesicles. Our method confirmed the large size of mPFC PSs and a linear correlation between presynaptic features of typical hippocampal synapses. Moreover, a greater number of docked vesicles in PSs may promote a high synaptic strength of these synapses. Copyright © 2013 Wiley Periodicals, Inc.
Spatiotemporal regulation of ATP and Ca2+ dynamics in vertebrate rod and cone ribbon synapses
Johnson, Jerry E.; Perkins, Guy A.; Giddabasappa, Anand; Chaney, Shawntay; Xiao, Weimin; White, Andrew D.; Brown, Joshua M.; Waggoner, Jenna; Ellisman, Mark H.
2007-01-01
Purpose In conventional neurons, Ca2+ enters presynaptic terminals during an action potential and its increased local concentration triggers transient exocytosis. In contrast, vertebrate photoreceptors are nonspiking neurons that maintain sustained depolarization and neurotransmitter release from ribbon synapses in darkness and produce light-dependent graded hyperpolarizing responses. Rods transmit single photon responses with high fidelity, whereas cones are less sensitive and exhibit faster response kinetics. These differences are likely due to variations in presynaptic Ca2+ dynamics. Metabolic coupling and cross-talk between mitochondria, endoplasmic reticulum (ER), plasma membrane Ca2+ ATPase (PMCA), and Na+-Ca2+ exchanger (NCX) coordinately control presynaptic ATP production and Ca2+ dynamics. The goal of our structural and functional studies was to determine the spatiotemporal regulation of ATP and Ca2+ dynamics in rod spherules and cone pedicles. Methods Central retina tissue from C57BL/6 mice was used. Laser scanning confocal microscopy (LSCM) experiments were conducted on fixed-frozen vertical sections. Primary antibodies were selected for their tissue/cellular specificity and ability to recognize single, multiple or all splice variants of selected isoforms. Electron microscopy (EM) and 3-D electron tomography (ET) studies used our standard procedures on thin- and thick-sectioned retinas, respectively. Calibrated fluo-3-Ca2+ imaging experiments of dark- and light-adapted rod and cone terminals in retinal slices were conducted. Results Confocal microscopy showed that mitochondria, ER, PMCA, and NCX1 exhibited distinct retinal lamination patterns and differential distribution in photoreceptor synapses. Antibodies for three distinct mitochondrial compartments differentially labeled retinal areas with high metabolic demand: rod and cone inner segments, previously undescribed cone juxtanuclear mitochondria and the two plexiform layers. Rod spherule membranes uniformly and intensely stained for PMCA, whereas the larger cone pedicles preferentially stained for NCX1 at their active zones and PMCA near their mitochondria. EM and ET revealed that mitochondria in rod spherules and cone pedicles differed markedly in their number, location, size, volume, and total cristae surface area, and cristae junction diameter. Rod spherules had one large ovoid mitochondrion located near its active zone, whereas cone pedicles averaged five medium-sized mitochondria clustered far from their active zones. Most spherules had one ribbon synapse, whereas pedicles contained numerous ribbon synapses. Fluo-3 imaging studies revealed that during darkness rod spherules maintained a lower [Ca2+] than cone pedicles, whereas during light adaptation pedicles rapidly lowered their [Ca2+] below that observed in spherules. Conclusions These findings indicate that ATP demand and mitochondrial ATP production are greater in cone pedicles than rod spherules. Rod spherules employ high affinity/low turnover PMCA and their mitochondrion to maintain a relatively low [Ca2+] in darkness, which increases their sensitivity and signal-to-noise ratio. In contrast, cone pedicles utilize low affinity/high turnover NCX to rapidly lower their high [Ca2+] during light adaptation, which increases their response kinetics. Spatiotemporal fluo-3-Ca2+ imaging results support our immunocytochemical results. The clustering of cone pedicle mitochondria likely provides increased protection from Ca2+ overload and permeability transition. In summary, these novel studies reveal that several integrated cellular and subcellular components interact to regulate ATP and Ca2+ dynamics in rod and cone synaptic terminals. These results should provide a greater understanding of in vivo photoreceptor synaptic terminal exocytosis/endocytosis, Ca2+ overload and therapies for retinal degenerations. PMID:17653034
Spatiotemporal regulation of ATP and Ca2+ dynamics in vertebrate rod and cone ribbon synapses.
Johnson, Jerry E; Perkins, Guy A; Giddabasappa, Anand; Chaney, Shawntay; Xiao, Weimin; White, Andrew D; Brown, Joshua M; Waggoner, Jenna; Ellisman, Mark H; Fox, Donald A
2007-06-15
In conventional neurons, Ca2+ enters presynaptic terminals during an action potential and its increased local concentration triggers transient exocytosis. In contrast, vertebrate photoreceptors are nonspiking neurons that maintain sustained depolarization and neurotransmitter release from ribbon synapses in darkness and produce light-dependent graded hyperpolarizing responses. Rods transmit single photon responses with high fidelity, whereas cones are less sensitive and exhibit faster response kinetics. These differences are likely due to variations in presynaptic Ca2+ dynamics. Metabolic coupling and cross-talk between mitochondria, endoplasmic reticulum (ER), plasma membrane Ca2+ ATPase (PMCA), and Na+-Ca2+ exchanger (NCX) coordinately control presynaptic ATP production and Ca2+ dynamics. The goal of our structural and functional studies was to determine the spatiotemporal regulation of ATP and Ca2+ dynamics in rod spherules and cone pedicles. Central retina tissue from C57BL/6 mice was used. Laser scanning confocal microscopy (LSCM) experiments were conducted on fixed-frozen vertical sections. Primary antibodies were selected for their tissue/cellular specificity and ability to recognize single, multiple or all splice variants of selected isoforms. Electron microscopy (EM) and 3-D electron tomography (ET) studies used our standard procedures on thin- and thick-sectioned retinas, respectively. Calibrated fluo-3-Ca2+ imaging experiments of dark- and light-adapted rod and cone terminals in retinal slices were conducted. Confocal microscopy showed that mitochondria, ER, PMCA, and NCX1 exhibited distinct retinal lamination patterns and differential distribution in photoreceptor synapses. Antibodies for three distinct mitochondrial compartments differentially labeled retinal areas with high metabolic demand: rod and cone inner segments, previously undescribed cone juxtanuclear mitochondria and the two plexiform layers. Rod spherule membranes uniformly and intensely stained for PMCA, whereas the larger cone pedicles preferentially stained for NCX1 at their active zones and PMCA near their mitochondria. EM and ET revealed that mitochondria in rod spherules and cone pedicles differed markedly in their number, location, size, volume, and total cristae surface area, and cristae junction diameter. Rod spherules had one large ovoid mitochondrion located near its active zone, whereas cone pedicles averaged five medium-sized mitochondria clustered far from their active zones. Most spherules had one ribbon synapse, whereas pedicles contained numerous ribbon synapses. Fluo-3 imaging studies revealed that during darkness rod spherules maintained a lower [Ca2+] than cone pedicles, whereas during light adaptation pedicles rapidly lowered their [Ca2+] below that observed in spherules. These findings indicate that ATP demand and mitochondrial ATP production are greater in cone pedicles than rod spherules. Rod spherules employ high affinity/low turnover PMCA and their mitochondrion to maintain a relatively low [Ca2+] in darkness, which increases their sensitivity and signal-to-noise ratio. In contrast, cone pedicles utilize low affinity/high turnover NCX to rapidly lower their high [Ca2+] during light adaptation, which increases their response kinetics. Spatiotemporal fluo-3-Ca2+ imaging results support our immunocytochemical results. The clustering of cone pedicle mitochondria likely provides increased protection from Ca2+ overload and permeability transition. In summary, these novel studies reveal that several integrated cellular and subcellular components interact to regulate ATP and Ca2+ dynamics in rod and cone synaptic terminals. These results should provide a greater understanding of in vivo photoreceptor synaptic terminal exocytosis/endocytosis, Ca2+ overload and therapies for retinal degenerations.
NASA Technical Reports Server (NTRS)
Johnson, B.; Cavanaugh, J.; Smith, J.; Esaias, W.
1988-01-01
The Ocean Data Acquisition System (ODAS) is a low cost instrument with potential commercial application. It is easily mounted on a small aircraft and flown over the coastal zone ocean to remotely measure sea surface temperature and three channels of ocean color information. From this data, chlorophyll levels can be derived for use by ocean scientists, fisheries, and environmental offices. Data can be transmitted to shipboard for real-time use with sea truth measurements, ocean productivity estimates and fishing fleet direction. The aircraft portion of the system has two primary instruments: an IR radiometer to measure sea surface temperature and a three channel visible spectro-radiometer for 460, 490, and 520 nm wavelength measurements from which chlorophyll concentration can be derived. The aircraft package contains a LORAN-C unit for aircraft location information, clock, on-board data processor and formatter, digital data storage, packet radio terminal controller, and radio transceiver for data transmission to a ship. The shipboard package contains a transceiver, packet terminal controller, data processing and storage capability, and printer. Both raw data and chlorophyll concentrations are available for real-time analysis.
Bassoon-disruption slows vesicle replenishment and induces homeostatic plasticity at a CNS synapse
Mendoza Schulz, Alejandro; Jing, Zhizi; María Sánchez Caro, Juan; Wetzel, Friederike; Dresbach, Thomas; Strenzke, Nicola; Wichmann, Carolin; Moser, Tobias
2014-01-01
Endbulb of Held terminals of auditory nerve fibers (ANF) transmit auditory information at hundreds per second to bushy cells (BCs) in the anteroventral cochlear nucleus (AVCN). Here, we studied the structure and function of endbulb synapses in mice that lack the presynaptic scaffold bassoon and exhibit reduced ANF input into the AVCN. Endbulb terminals and active zones were normal in number and vesicle complement. Postsynaptic densities, quantal size and vesicular release probability were increased while vesicle replenishment and the standing pool of readily releasable vesicles were reduced. These opposing effects canceled each other out for the first evoked EPSC, which showed unaltered amplitude. We propose that ANF activity deprivation drives homeostatic plasticity in the AVCN involving synaptic upscaling and increased intrinsic BC excitability. In vivo recordings from individual mutant BCs demonstrated a slightly improved response at sound onset compared to ANF, likely reflecting the combined effects of ANF convergence and homeostatic plasticity. Further, we conclude that bassoon promotes vesicular replenishment and, consequently, a large standing pool of readily releasable synaptic vesicles at the endbulb synapse. PMID:24442636
Tracking urban human activity from mobile phone calling patterns
Ghosh, Asim; Bhattacharya, Kunal; Dunbar, Robin I. M.; Kaski, Kimmo
2017-01-01
Timings of human activities are marked by circadian clocks which in turn are entrained to different environmental signals. In an urban environment the presence of artificial lighting and various social cues tend to disrupt the natural entrainment with the sunlight. However, it is not completely understood to what extent this is the case. Here we exploit the large-scale data analysis techniques to study the mobile phone calling activity of people in large cities to infer the dynamics of urban daily rhythms. From the calling patterns of about 1,000,000 users spread over different cities but lying inside the same time-zone, we show that the onset and termination of the calling activity synchronizes with the east-west progression of the sun. We also find that the onset and termination of the calling activity of users follows a yearly dynamics, varying across seasons, and that its timings are entrained to solar midnight. Furthermore, we show that the average mid-sleep time of people living in urban areas depends on the age and gender of each cohort as a result of biological and social factors. PMID:29161270
Tracking urban human activity from mobile phone calling patterns.
Monsivais, Daniel; Ghosh, Asim; Bhattacharya, Kunal; Dunbar, Robin I M; Kaski, Kimmo
2017-11-01
Timings of human activities are marked by circadian clocks which in turn are entrained to different environmental signals. In an urban environment the presence of artificial lighting and various social cues tend to disrupt the natural entrainment with the sunlight. However, it is not completely understood to what extent this is the case. Here we exploit the large-scale data analysis techniques to study the mobile phone calling activity of people in large cities to infer the dynamics of urban daily rhythms. From the calling patterns of about 1,000,000 users spread over different cities but lying inside the same time-zone, we show that the onset and termination of the calling activity synchronizes with the east-west progression of the sun. We also find that the onset and termination of the calling activity of users follows a yearly dynamics, varying across seasons, and that its timings are entrained to solar midnight. Furthermore, we show that the average mid-sleep time of people living in urban areas depends on the age and gender of each cohort as a result of biological and social factors.
Propagation of back-arc extension into the arc lithosphere in the southern New Hebrides volcanic arc
NASA Astrophysics Data System (ADS)
Patriat, M.; Collot, J.; Danyushevsky, L.; Fabre, M.; Meffre, S.; Falloon, T.; Rouillard, P.; Pelletier, B.; Roach, M.; Fournier, M.
2015-09-01
New geophysical data acquired during three expeditions of the R/V Southern Surveyor in the southern part of the North Fiji Basin allow us to characterize the deformation of the upper plate at the southern termination of the New Hebrides subduction zone, where it bends eastward along the Hunter Ridge. Unlike the northern end of the Tonga subduction zone, on the other side of the North Fiji Basin, the 90° bend does not correspond to the transition from a subduction zone to a transform fault, but it is due to the progressive retreat of the New Hebrides trench. The subduction trench retreat is accommodated in the upper plate by the migration toward the southwest of the New Hebrides arc and toward the south of the Hunter Ridge, so that the direction of convergence remains everywhere orthogonal to the trench. In the back-arc domain, the active deformation is characterized by propagation of the back-arc spreading ridge into the Hunter volcanic arc. The N-S spreading axis propagates southward and penetrates in the arc, where it connects to a sinistral strike-slip zone via an oblique rift. The collision of the Loyalty Ridge with the New Hebrides arc, less than two million years ago, likely initiated this deformation pattern and the fragmentation of the upper plate. In this particular geodynamic setting, with an oceanic lithosphere subducting beneath a highly sheared volcanic arc, a wide range of primitive subduction-related magmas has been produced including adakites, island arc tholeiites, back-arc basin basalts, and medium-K subduction-related lavas.
Benjamin, M; Newell, R L; Evans, E J; Ralphs, J R; Pemberton, D J
1992-01-01
The terminal portions of the tendon of brachialis, and the distal tendons of biceps brachii and triceps, were compared by routine histology. All tendons came from elderly dissecting room cadavers. There were pronounced quantitative differences between the 3 tendons in (1) the thickness of the attachment-zone fibrocartilage, (2) the thickness of cortical calcified tissue, and (3) the percentage of bone to marrow. There was significantly more uncalcified fibrocartilage at the attachment of biceps than at the other sites, reflecting greater range of movement of the tendon at this site. The thickness of cortical calcified tissue and the percentage of bone to marrow were significantly greater at the attachment of brachialis than either biceps or triceps. The large quantities of bone at the attachment of brachialis may be related more to the importance of the coronoid process in buttressing the elbow joint than to any special requirement for large amounts of calcified tissue at the tendon attachment. Near its attachment zone, the biceps tendon splits into superficial and deep laminae that are distinct from the macroscopic subdivision of this tendon. It is suggested that the lamination may facilitate the movements of pronation and supination. In support of this, the deep portion of the superficial lamina contained fibrocartilage where it rubbed against the attachment-zone of the deep lamina. In one body, the fibrocartilage of the biceps attachment-zone was subject to degenerative changes, including cell clumping and matrix fissuring. Images Fig. 2 Fig. 3 PMID:1506288
Variable modes of rifting in the eastern Basin and Range, USA from on-fault geological evidence
NASA Astrophysics Data System (ADS)
Stahl, T.; Niemi, N. A.
2017-12-01
Continental rifts are often divided along their axes into magmatic (or magma-assisted) and amagmatic (or magma-poor) segments. Less is known about magmatic versus non-magmatic extension across `wide' continental rift margins like the Basin and Range province of the USA. Paleoseismic trench investigations, Quaternary geochronology (10Be and 3He exposure-age, luminescence, and 40Ar/39Ar dating), and high-resolution topographic surveys (terrestrial laser scanning and UAV photogrammetry) were used to assess the timing and spatial variability of faulting at the Basin and Range-Colorado Plateau transition zone in central Utah. Results show that while the majority of strain is accommodated by a single, range- and province-bounding fault (the Wasatch fault zone, WFZ, slip rate of c. 3-4 mm yr-1), a transition to magma-assisted rifting occurs near the WFZ southern termination marked by a diffuse zone of faults associated with Pliocene to Holocene volcanism. Paleoseismic analysis of faults within and adjacent to this zone reveal recent (<18 ka) surface-ruptures on these faults. A single event displacement of 10-15 m for the Tabernacle fault at c. 15-18 ka (3He exposure-age) and large fault displacement gradients imply that slip was coeval with lava emplacement and that the faults in this region are linked, at least in part, to dike injection in the uppermost crust rather than slip at seismogenic depths. These results have implications for the controversial nature of regional seismic hazard and the structural evolution of the eastern Basin and Range.
Spatiotemporal Patterns of Fault Slip Rates Across the Central Sierra Nevada Frontal Fault Zone
NASA Astrophysics Data System (ADS)
Rood, D. H.; Burbank, D.; Finkel, R. C.
2010-12-01
We examine patterns in fault slip rates through time and space across the transition from the Sierra Nevada to the Eastern California Shear Zone-Walker Lane belt. At each of four sites along the eastern Sierra Nevada frontal fault zone between 38-39° N latitude, geomorphic markers, such as glacial moraines and outwash terraces, are displaced by a suite of range-front normal faults. Using geomorphic mapping, surveying, and Be-10 surface exposure dating, we define mean fault slip rates, and by utilizing markers of different ages (generally, ~20 ka and ~150 ka), we examine rates through time and interactions among multiple faults over 10-100 ky timescales. At each site for which data are available for the last ~150 ky, mean slip rates across the Sierra Nevada frontal fault zone have probably not varied by more than a factor of two over time spans equal to half of the total time interval (~20 ky and ~150 ky timescales): 0.3 ± 0.1 mm/yr (mode and 95% CI) at both Buckeye Creek in the Bridgeport basin and Sonora Junction; and 0.4 +0.3/-0.1 mm/yr along the West Fork of the Carson River at Woodfords. Our data permit that rates are relatively constant over the time scales examined. In contrast, slip rates are highly variable in space over the last ~20 ky. Slip rates decrease by a factor of 3-5 northward over a distance of ~20 km between the northern Mono Basin (1.3 +0.6/-0.3 mm/yr at Lundy Canyon site) and the Bridgeport Basin (0.3 ± 0.1 mm/yr). The 3-fold decrease in the slip rate on the Sierra Nevada frontal fault zone northward from Mono Basin reflects a change in the character of faulting north of the Mina Deflection as extension is transferred eastward onto normal faults between the Sierra Nevada and Walker Lane belt. A compilation of regional deformation rates reveal that the spatial pattern of extension rates changes along strike of the Eastern California Shear Zone-Walker Lane belt. South of the Mina Deflection, extension is accommodated within a diffuse zone of normal and oblique faults, with extension rates increasing northward on the Fish Lake Valley fault. Where faults of the Eastern California Shear Zone terminate northward into the Mina Deflection, extension rates increase northward along the Sierra Nevada frontal fault zone to ~0.7 mm/yr in northern Mono Basin. This spatial pattern suggests that extension is transferred from faults systems to the east (e.g. Fish Lake Valley fault) and localized on the Sierra Nevada frontal fault zone as Eastern California Shear Zone-Walker Lane belt faulting is transferred through the Mina Deflection.
NASA Astrophysics Data System (ADS)
Shafiei Bafti, Shahram; Mohajjel, Mohammad
2015-04-01
The structural evolution of the Sanandaj-Sirjan zone is the result of the convergence of the Iranian microcontinent and the Afro-Arabian continent. The study area at Khabr in the SE Sanandaj-Sirjan zone, in the hinterland of the Zagros orogen, consists of Paleozoic, Mesozoic and Cenozoic rocks. In this area, deformation phases were distinguished in different rock units based on structural and stratigraphical evidence, and the deformational events are divided into two stages: (1) a Late Triassic event and (2) a Late Cretaceous to Miocene event. The Late Triassic deformation event caused regional metamorphism in the Paleozoic units. These units are overlain by unmetamorphosed Jurassic clastic sequences. Fabrics and structural evidence confirm that the F1 folding recumbent and refolded folds were synchronous with the metamorphism of the Paleozoic units and terminated in the Early Jurassic. The time table of the orogenic phases shows that this deformation event is related to the Cimmerian orogenic phase. From a geodynamic point of view, the early Cimmerian deformation in the southeastern Iranian margin suggests that the SE Sanandaj-Sirjan zone was an active margin at that time. The early Cimmerian discordance recorded the onset of a contractional component related to the oblique subduction of Neo-Tethys beneath the central Iranian microcontinent. Structures related to the Late Cretaceous to Miocene deformation phase are observed in Jurassic to Oligocene units, which contain moderately inclined and plunging folds. Comparing these folds with domains of deformation generated in models of transpression shows that the folding was caused by a combination of contractional and dip-slip components of movement, eventually resulting in the formation of a thrust system. The Khabr thrust systems consist of five sheets of oblique thrusts, duplex structures and shear zones. The shear zones generally strike E-W and dip moderately N (30°-40°). The occurrence of asymmetric folds with hinges that are either parallel to strike or plunge down dip demonstrates an oblique-slip component in these thrust shear zones. The stretching lineation in the mylonites within the shear zones is defined by the long axes of ellipsoidal grains of quartz, calcite, plagioclase and garnet. In general, stretching lineations trend from N40°W to N80°W with an intermediate (35°) plunge. The geometry of foliation and lineation within these shear zones shows the effect of dip- and oblique-slip shearing. Deformation continued with strike-slip faulting becoming important during the last stages of deformation from the Miocene to the present day. The results of this study demonstrate that the evolution of the SE Sanandaj-Sirjan zone, from Late Triassic to Miocene, is compatible with an inclined dextral transpression along this zone.
Role of Defects on Regioselectivity of Nano Pristine Graphene.
Kudur Jayaprakash, Gururaj; Casillas, Norberto; Astudillo-Sánchez, Pablo D; Flores-Moreno, Roberto
2016-11-17
Here analytical Fukui functions based on density functional theory are applied to investigate the redox reactivity of pristine and defected graphene lattices. A carbon H-terminated graphene structure (with 96 carbon atoms) and a graphene defected surface with Stone-Wales rearrangement and double vacancy defects are used as models. Pristine sp 2 -hybridized, hexagonal arranged carbon atoms exhibit a symmetric reactivity. In contrast, common carbon atoms at reconstructed polygons in Stone-Wales and double vacancy graphene display large reactivity variations. The improved reactivity and the regioselectivity at defected graphene is correlated to structural changes that caused carbon-carbon bond length variations at defected zones.
2012-10-16
PORT CANAVERAL, Fla. – Bob Cabana, director of the Kennedy Space Center in Florida, spoke during opening ceremonies at the Historically Underutilized Business Zone, or HUBZone, Industry Day and Expo 2012. The event was hosted for business leaders who are interested in learning about government contracting opportunities and what local and national vendors have to offer. The expo was held in Cruise Terminal 4 at Port Canaveral, Fla. The annual trade show is sponsored by Kennedy's Prime Contractor Board, the U.S. Air Force 45th Space Wing and the Canaveral Port Authority. It featured about 175 large and small businesses and government exhibitors from Brevard County and across the nation. Photo credit: NASA/ Kim Shiflett
2012-10-16
PORT CANAVERAL, Fla. – Bruce Deardoff, Canaveral Port Authority Commission chairman, spoke during opening ceremonies at the Historically Underutilized Business Zone, or HUBZone, Industry Day and Expo 2012. The event was hosted for business leaders who are interested in learning about government contracting opportunities and what local and national vendors have to offer. The expo was held in Cruise Terminal 4 at Port Canaveral, Fla. The annual trade show is sponsored by Kennedy's Prime Contractor Board, the U.S. Air Force 45th Space Wing and the Canaveral Port Authority. It featured about 175 large and small businesses and government exhibitors from Brevard County and across the nation. Photo credit: NASA/ Kim Shiflett
2012-10-16
PORT CANAVERAL, Fla. – Bob Cabana, director of the Kennedy Space Center in Florida, spoke during opening ceremonies at the Historically Underutilized Business Zone, or HUBZone, Industry Day and Expo 2012. The event was hosted for business leaders who are interested in learning about government contracting opportunities and what local and national vendors have to offer. The expo was held in Cruise Terminal 4 at Port Canaveral, Fla. The annual trade show is sponsored by Kennedy's Prime Contractor Board, the U.S. Air Force 45th Space Wing and the Canaveral Port Authority. It featured about 175 large and small businesses and government exhibitors from Brevard County and across the nation. Photo credit: NASA/ Kim Shiflett
2012-10-16
PORT CANAVERAL, Fla. – David Radzanowski, NASA chief of staff, spoke during opening ceremonies at the Historically Underutilized Business Zone, or HUBZone, Industry Day and Expo 2012. The event was hosted for business leaders who are interested in learning about government contracting opportunities and what local and national vendors have to offer. The expo was held in Cruise Terminal 4 at Port Canaveral, Fla. The annual trade show is sponsored by Kennedy's Prime Contractor Board, the U.S. Air Force 45th Space Wing and the Canaveral Port Authority. It featured about 175 large and small businesses and government exhibitors from Brevard County and across the nation. Photo credit: NASA/ Kim Shiflett
Tamm-plasmon polaritons in one-dimensional photonic quasi-crystals.
Shukla, Mukesh Kumar; Das, Ritwick
2018-02-01
We present an investigation to ascertain the existence of Tamm-plasmon-polariton-like modes in one-dimensional (1D) quasi-periodic photonic systems. Photonic bandgap formation in quasi-crystals is essentially a consequence of long-range periodicity exhibited by multilayers and, thus, it can be explained using the dispersion relation in the Brillouin zone. Defining a "Zak"-like topological phase in 1D quasi-crystals, we propose a recipe to ascertain the existence of Tamm-like photonic surface modes in a metal-terminated quasi-crystal lattice. Additionally, we also explore the conditions of efficient excitation of such surface modes along with their dispersion characteristics.
Matthews, M A; Hoffmann, K D; Hernandez, T V
1989-01-01
Ulex europaeus agglutinin I (UEA-I) is a plant lectin with an affinity for L-fucosyl residues in the chains of lactoseries oligosaccharides associated with medium- and smaller-diameter dorsal root ganglion neurons and their axonal processes. These enter Lissauer's tract and terminate within the superficial laminae of the spinal cord overlapping projections known to have a nociceptive function. This implies that the surface coatings of neuronal membranes may have a relationship with functional modalities. The present investigation further examined this concept by studying a neuronal projection with a nociceptive function to determine whether fucosyl-lactoseries residues were incorporated in its primary afferent terminals. Transganglionic transport of horseradish peroxidase (HRP) following injection into tooth pulp chambers was employed to demonstrate dental pulp terminals in the trigeminal spinal complex, while peroxidase and fluorescent tags were used concomitantly to stain for UEA-I. Double immunolabeling for substance P (SP) and gamma-aminobutyric acid (GABA) using peroxidase and colloidal gold allowed a comparison of the distribution of a known excitatory nociceptive transmitter with that of UEA-I binding in specific subnuclei. Synaptic interrelationships between UEA-I positive dental pulp primary afferent inputs and specific inhibitory terminals were also examined. SP immunoreactivity occurred in laminae I and outer lamina II (IIo) of subnucleus caudalis (Vc) and in the ventrolateral and lateral marginal region of the caudal half of subnucleus interpolaris (Vi), including the periobex area in which Vi is slightly overlapped on its lateral aspect by cellular elements of Vc. The adjacent interstitial nucleus (IN) also showed an intense immunoreactivity for this peptide antibody. UEA-I binding displayed a similar distribution pattern in both Vc and Vi, but extended into lamina IIi and the superficial part of Lamina III in Vc. Dental pulp terminals were found to have a comparable distribution; however, many extended into the dorsal portion of the caudal half of Vi and the ventromedial quadrant of rostral Vi. Electron-microscopic analysis showed that transganglionically labeled dental pulp terminals contained ovoid, complex membrane-bound vacuoles laden with transported HRP. The preterminal axon and synaptic membranes of those dental pulp terminals located in zones of Vc and Vi displaying an affinity for UEA-I were usually characterized by a patchy, electron-dense coating of the peroxidase tag. SP was demonstrated ultrastructurally with Protein-A colloidal gold (3-nm particles), whereas GABA immunoreactivity was revealed by the avidin-biotin-peroxidase method.(ABSTRACT TRUNCATED AT 400 WORDS)
Minimum airflow reset of single-duct VAV terminal boxes
NASA Astrophysics Data System (ADS)
Cho, Young-Hum
Single duct Variable Air Volume (VAV) systems are currently the most widely used type of HVAC system in the United States. When installing such a system, it is critical to determine the minimum airflow set point of the terminal box, as an optimally selected set point will improve the level of thermal comfort and indoor air quality (IAQ) while at the same time lower overall energy costs. In principle, this minimum rate should be calculated according to the minimum ventilation requirement based on ASHRAE standard 62.1 and maximum heating load of the zone. Several factors must be carefully considered when calculating this minimum rate. Terminal boxes with conventional control sequences may result in occupant discomfort and energy waste. If the minimum rate of airflow is set too high, the AHUs will consume excess fan power, and the terminal boxes may cause significant simultaneous room heating and cooling. At the same time, a rate that is too low will result in poor air circulation and indoor air quality in the air-conditioned space. Currently, many scholars are investigating how to change the algorithm of the advanced VAV terminal box controller without retrofitting. Some of these controllers have been found to effectively improve thermal comfort, indoor air quality, and energy efficiency. However, minimum airflow set points have not yet been identified, nor has controller performance been verified in confirmed studies. In this study, control algorithms were developed that automatically identify and reset terminal box minimum airflow set points, thereby improving indoor air quality and thermal comfort levels, and reducing the overall rate of energy consumption. A theoretical analysis of the optimal minimum airflow and discharge air temperature was performed to identify the potential energy benefits of resetting the terminal box minimum airflow set points. Applicable control algorithms for calculating the ideal values for the minimum airflow reset were developed and applied to actual systems for performance validation. The results of the theoretical analysis, numeric simulations, and experiments show that the optimal control algorithms can automatically identify the minimum rate of heating airflow under actual working conditions. Improved control helps to stabilize room air temperatures. The vertical difference in the room air temperature was lower than the comfort value. Measurements of room CO2 levels indicate that when the minimum airflow set point was reduced it did not adversely affect the indoor air quality. According to the measured energy results, optimal control algorithms give a lower rate of reheating energy consumption than conventional controls.
NASA Technical Reports Server (NTRS)
Colgan, William; Rajaram, Harihar; Anderson, Robert; Steffen. Konrad; Phillips, Thomas; Zwally, H. Jay; Abdalati, Waleed
2012-01-01
We apply a novel one-dimensional glacier hydrology model that calculates hydraulic head to the tidewater-terminating Sermeq Avannarleq flowline of the Greenland ice sheet. Within a plausible parameter space, the model achieves a quasi-steady-state annual cycle in which hydraulic head oscillates close to flotation throughout the ablation zone. Flotation is briefly achieved during the summer melt season along a approx.17 km stretch of the approx.50 km of flowline within the ablation zone. Beneath the majority of the flowline, subglacial conduit storage closes (i.e. obtains minimum radius) during the winter and opens (i.e. obtains maximum radius) during the summer. Along certain stretches of the flowline, the model predicts that subglacial conduit storage remains open throughout the year. A calculated mean glacier water residence time of approx.2.2 years implies that significant amounts of water are stored in the glacier throughout the year. We interpret this residence time as being indicative of the timescale over which the glacier hydrologic system is capable of adjusting to external surface meltwater forcings. Based on in situ ice velocity observations, we suggest that the summer speed-up event generally corresponds to conditions of increasing hydraulic head during inefficient subglacial drainage. Conversely, the slowdown during fall generally corresponds to conditions of decreasing hydraulic head during efficient subglacial drainage.
NASA Astrophysics Data System (ADS)
Harris, Peter T.; Barrie, J. Vaughn; Conway, Kim W.; Greene, H. Gary
2014-06-01
Faulting commonly influences the geomorphology of submarine canyons that occur on active continental margins. Here, we examine the geomorphology of canyons located on the continental margin off Haida Gwaii, British Columbia, that are truncated on the mid-slope (1200-1400 m water depth) by the Queen Charlotte Fault Zone (QCFZ). The QCFZ is an oblique strike-slip fault zone that has rates of lateral motion of around 50-60 mm/yr and a small convergent component equal to about 3 mm/yr. Slow subduction along the Cascadia Subduction Zone has accreted a prism of marine sediment against the lower slope (1500-3500 m water depth), forming the Queen Charlotte Terrace, which blocks the mouths of submarine canyons formed on the upper slope (200-1400 m water depth). Consequently, canyons along this margin are short (4-8 km in length), closely spaced (around 800 m), and terminate uniformly along the 1400 m isobath, coinciding with the primary fault trend of the QCFZ. Vertical displacement along the fault has resulted in hanging canyons occurring locally. The Haida Gwaii canyons are compared and contrasted with the Sur Canyon system, located to the south of Monterey Bay, California, on a transform margin, which is not blocked by any accretionary prism, and where canyons thus extend to 4000 m depth, across the full breadth of the slope.
Reunov, Arkadiy; Reunov, Anatoliy; Pimenova, Evgenia; Reunova, Yulia; Menchinskaiya, Ekaterina; Lapshina, Larisa; Aminin, Dmitry
2018-06-05
An expression of calpain and caspase-1 as well as the concomitant ultrastructural alterations were investigated during necrosis of the mouse Ehrlich ascites carcinoma. The calpain expression was registered at 0 h and 1 h although caspase-1 did not induce any signals during these time periods. The rise of the cytoplasmic lytic zones contacted by calpain antibodies was identified as a morphologic event corresponding to the expression of calpain. Lytic zone's distribution followed by the appearance of the calpain/caspase-1 clusters assigned for lysis of the Golgi vesicles and ER. Also, the microapocrine secretion of the vesicles containing the calpain/caspase-1 clusters was detected. Further, the lysis of the plasma membrane occurred due to progression of intracellular lysis. Rupture of the plasma membrane resulted in the termination of secretion and dissemination of cell contents. The nuclei still had their normal shape. Nuclear lysis continued to rise with intranuclear lytic zones, of which the progression was accompanied with the presence of calpain/caspase-1 clusters. The data contribute to the concept of the initial role of calpain for tumor cell destruction, provide first evidence of the calpain/caspase-1 pathway in tumor cells, and highlight microapocrine secretion as a possible tumor cell death signalling mechanism. Copyright © 2018 Elsevier B.V. All rights reserved.
Blood flow characteristics in a terminal basilar tip aneurysm prior to its fatal rupture
Sforza, D.M.; Putman, C.M.; Scrivano, E.; Lylyk, P.; Cebral, J.R.
2010-01-01
Background and Purpose The development and validation of methods to stratify the risk of rupture of cerebral aneurysms is highly desired since current treatment risks can exceed the natural risk of rupture. Because unruptured aneurysms are typically treated before they rupture, it is very difficult to connect the proposed risk indices to the rupture of an individual aneurysm. The purpose of this case study was to analyze the hemodynamic environment of a saccular aneurysm of the terminal morphology sub-type that was imaged just prior to its rupture and to test whether the hemodynamic characteristics would designate this particular aneurysm as at high risk. Methods A patient-specific computational fluid dynamics model was constructed from 3D rotational angiography images acquired just hours before the aneurysm ruptured. A pulsatile flow calculation was performed and hemodynamic characteristics previously connected to rupture were analyzed. Results It was found that the aneurysm had a concentrated inflow stream, small impingement region, complex intra-aneurysmal flow structure, asymmetric flow split from the parent vessel to the aneurysm and daughter branches, and high levels of aneurysmal wall shear stress near the impaction zone. Conclusions The hemodynamics characteristics observed in this aneurysm right before its rupture are consistent with previous studies correlating aneurysm rupture and hemodynamic patterns in saccular and terminal aneurysms. This study supports the notion that hemodynamic information may be used to help stratify the rupture risk of cerebral aneurysms. PMID:20150312
DOE Office of Scientific and Technical Information (OSTI.GOV)
Simmons, N. A.; Myers, S. C.; Johannesson, G.
In this study, ancient subducted tectonic plates have been observed in past seismic images of the mantle beneath North America and Eurasia, and it is likely that other ancient slab structures have remained largely hidden, particularly in the seismic-data-limited regions beneath the vast oceans in the Southern Hemisphere. Here we present a new global tomographic image, which shows a slab-like structure beneath the southern Indian Ocean with coherency from the upper mantle to the core-mantle boundary region—a feature that has never been identified. We postulate that the structure is an ancient tectonic plate that sank into the mantle along anmore » extensive intraoceanic subduction zone that migrated southwestward across the ancient Tethys Ocean in the Mesozoic Era. Slab material still trapped in the transition zone is positioned near the edge of East Gondwana at 140 Ma suggesting that subduction terminated near the margin of the ancient continent prior to breakup and subsequent dispersal of its subcontinents.« less
Simmons, N. A.; Myers, S. C.; Johannesson, G.; ...
2015-11-14
In this study, ancient subducted tectonic plates have been observed in past seismic images of the mantle beneath North America and Eurasia, and it is likely that other ancient slab structures have remained largely hidden, particularly in the seismic-data-limited regions beneath the vast oceans in the Southern Hemisphere. Here we present a new global tomographic image, which shows a slab-like structure beneath the southern Indian Ocean with coherency from the upper mantle to the core-mantle boundary region—a feature that has never been identified. We postulate that the structure is an ancient tectonic plate that sank into the mantle along anmore » extensive intraoceanic subduction zone that migrated southwestward across the ancient Tethys Ocean in the Mesozoic Era. Slab material still trapped in the transition zone is positioned near the edge of East Gondwana at 140 Ma suggesting that subduction terminated near the margin of the ancient continent prior to breakup and subsequent dispersal of its subcontinents.« less
Bacterial dominance in subseafloor sediments characterized by methane hydrates
Briggs, Brandon R.; Inagaki, Fumio; Morono, Yuki; Futagami, Taiki; Huguet, Carme; Rosell-Mele, Antoni; Lorenson, T.D.; Colwell, Frederick S.
2015-01-01
The degradation of organic carbon in subseafloor sediments on continental margins contributes to the largest reservoir of methane on Earth. Sediments in the Andaman Sea are composed of ~ 1% marine-derived organic carbon and biogenic methane is present. Our objective was to determine microbial abundance and diversity in sediments that transition the gas hydrate occurrence zone (GHOZ) in the Andaman Sea. Microscopic cell enumeration revealed that most sediment layers harbored relatively low microbial abundance (103–105 cells cm−3). Archaea were never detected despite the use of both DNA- and lipid-based methods. Statistical analysis of terminal restriction fragment length polymorphisms revealed distinct microbial communities from above, within, and below the GHOZ, and GHOZ samples were correlated with a decrease in organic carbon. Primer-tagged pyrosequences of bacterial 16S rRNA genes showed that members of the phylum Firmicutes are predominant in all zones. Compared with other seafloor settings that contain biogenic methane, this deep subseafloor habitat has a unique microbial community and the low cell abundance detected can help to refine global subseafloor microbial abundance.
Development of comprehensive remediation standards at San Francisco International Airport
DOE Office of Scientific and Technical Information (OSTI.GOV)
Grosso, A.; Lawler, M.; Meek, S.
1995-12-31
An ongoing expansion at the San Francisco International Airport (Airport) will result in a 35 percent increase in both terminal square footage and passenger handling capability. Facility relocation and construction are set to begin in October, 1995. Appropriate cleanup of contaminated soil and groundwater must be completed prior to this activity. Remedial goals for this major industrial facility must be protective of both human health and the environment. A risk-based strategy for the development of recommended cleanup objectives has been developed with the support of state regulatory agencies. This strategy includes Remediation Management Zones (RMZs), distinct regions at the Airportmore » with different remedial goals based on the associated risk to water quality, human health, and the environment. The RMZs and the final cleanup objectives for the Airport will be finalized by mid-1995, and will be used to govern future cleanup efforts at the site. This presentation will describe the history of the project, the determination of human health and ecological buffer zones, and the integration of these two concepts to produce cleanup objectives fully supported by the state regulatory authority.« less
Zhao, Yimeng; Sun, Liangliang; Zhu, Guijie; Dovichi, Norman J
2016-10-07
We used reversed-phase liquid chromatography to separate the yeast proteome into 23 fractions. These fractions were then analyzed using capillary zone electrophoresis (CZE) coupled to a Q-Exactive HF mass spectrometer using an electrokinetically pumped sheath flow interface. The parameters of the mass spectrometer were first optimized for top-down proteomics using a mixture of seven model proteins; we observed that intact protein mode with a trapping pressure of 0.2 and normalized collision energy of 20% produced the highest intact protein signals and most protein identifications. Then, we applied the optimized parameters for analysis of the fractionated yeast proteome. From this, 580 proteoforms and 180 protein groups were identified via database searching of the MS/MS spectra. This number of proteoform identifications is two times larger than that of previous CZE-MS/MS studies. An additional 3,243 protein species were detected based on the parent ion spectra. Post-translational modifications including N-terminal acetylation, signal peptide removal, and oxidation were identified.
Dillon, William P.; Danforth, W.W.; Hutchinson, D.R.; Drury, R.M.; Taylor, M.H.; Booth, J.S.
1998-01-01
This paper is part of the special publication Gas hydrates: relevance to world margin stability and climatic change (eds J.P. Henriet and J. Mienert). An irregular, faulted, collapse depression about 38 x 18 km in extent is located on the crest of the Blake Ridge offshore from the south- eastern United States. Faults disrupt the sea floor and terminate or sole out about 40-500 m below the sea floor at the base of the gas hydrate stable zone, which is identified from the location of the bottom simulating reflection (BSR). Normal faults are common but reverse faults and folds also are widespread. Folds commonly convert upward into faults. Sediment diapirs and deposits of sediments that were erupted onto the sea floor are also present. Sea-floor depressions at faults may represent locations of liquid/gas vents. The collapse was probably caused by overpressures and by the decoupling of the overlying sediments by gassy muds that existed just beneath the zone of gas hydrate stability.
NASA Astrophysics Data System (ADS)
Wilmsen, Markus; Storm, Marisa; Fürsich, Franz Theodor; Majidifard, Mahmoud Reza
2013-12-01
Wilmsen, M., Storm, M., Fürsich, F.T. and Majidifard, M.R. 2013. Upper Albian and Cenomanian (Cretaceous) ammonites from the Debarsu Formation (Yazd Block, Central Iran). Acta Geologica Polonica, 63 (4), 489-513. Warszawa. New ammonite faunas consisting of 13 taxa provide the first reliable biostratigraphic dating of the Debarsu Formation of the Yazd Block, west-central Iran, indicating several levels in the Upper Albian and Lower Cenomanian, while a foraminiferal assemblage places the top of the Formation in the Middle Turonian. Among the identified ammonite taxa, Acompsoceras renevieri (Sharpe, 1857) is recorded from Iran for the first time. The upper part of the lower Upper Albian is proved by the occurrences of mortoniceratines of the Mortoniceras (M.) inflatum Zone in the lowermost part of the Debarsu Formation. For the upper Upper Albian (traditional Stoliczkaia dispar Zone), the M. (Subschloenbachia ) rostratum and M. (S.) perinflatum zones are proved by their index taxa. However, there is no evidence of the terminal Arrhaphoceras (Praeschloenbachia) briacensis Zone. The upper part of the lower Lower Cenomanian Mantelliceras mantelli Zone (M. saxbii Subzone) is proved by M. saxbii and M. cf. mantelli. Below, there is an ammonite- barren interval of ca. 100 m in thickness between M. (S.) perinflatum zonal strata and the M. saxbii Subzone. The upper Lower Cenomanian is documented by the presence of typically M. dixoni zonal ammonites such as Acompsoceras renevieri. Upper Cenomanian and Turonian ammonites have not been found in the upper part of the Debarsu Formation, but micro-biostratigraphic evidence (planktonic foraminifers) from the uppermost part of the formation indicate that the formation ranges into the Turonian. For the development of the major tectonic unconformity at the base of the overlying Haftoman Formation (which yielded Lower Coniacian inoceramids near its base), only 2-3 myr remain, stressing the geodynamic activity of Central Iran during mid-Cretaceous times.
Rumfelt, L L; McKinney, E C; Taylor, E; Flajnik, M F
2002-08-01
Secondary lymphoid tissue and immunoglobulin (Ig) production in mammals is not fully developed at birth, requiring time postnatally to attain all features required for adaptive immune responses. The immune system of newborn sharks - the oldest vertebrate group having adaptive immunity - also displays immature characteristics such as low serum IgM concentration and high levels of IgM1gj, an innate-like Ig. Primary and secondary lymphoid tissues in sharks and other cartilaginous fish were identified previously, but their cellular organization was not examined in detail. In this study of nurse shark lymphoid tissue, we demonstrate that the adult spleen contains well-defined, highly vascularized white pulp (WP) areas, composed of a central T-cell zone containing a major histocompatibility complex (MHC) class II+ dendritic cell (DC) network and a small number of Ig+ secretory cells, surrounded by smaller zones of surface Ig+ (sIg+) B cells. In neonates, splenic WPs are exclusively B-cell zones containing sIgM+-MHC class IIlow B cells; thus compartmentalized areas with T cells and DCs, as well as surface Ig novel antigen receptor (sIgNAR)-expressing B cells are absent at birth. Not until the pups are 5 months old do these WP areas become adult-like; concomitantly, sIgNAR+ B cells are readily detectable, indicating that this Ig class requires a 'mature immune-responsive environment'. The epigonal organ is the major site of neonatal B lymphopoiesis, based on the presence of developing B cells and recombination-activating gene 1 (RAG1)/terminal deoxynucleotidyl transferase (TdT) expression, indicative of antigen receptor rearrangement; such expression persists into adult life, whereas the spleen has negligible lymphopoietic activity. In adults but not neonates, many secretory B cells reside in the epigonal organ, suggesting, like in mammals, that B cells home to this primary lymphoid tissue after activation in other areas of the body.
NASA Astrophysics Data System (ADS)
Landing, Ed; Geyer, Gerd; Brasier, Martin D.; Bowring, Samuel A.
2013-08-01
Use of the first appearance datum (FAD) of a fossil to define a global chronostratigraphic unit's base can lead to intractable correlation and stability problems. FADs are diachronous—they reflect species' evolutionary history, dispersal, biofacies, preservation, collection, and taxonomy. The Cambrian Evolutionary Radiation is characterised by diachronous FADs, biofacies controls, and provincialism of taxa and ecological communities that confound a stable Lower Cambrian chronostratigraphy. Cambrian series and stage definitions require greater attention to assemblage zone successions and non-biostratigraphic, particularly carbon isotope, correlation techniques such as those that define the Ediacaran System base. A redefined, basal Cambrian Trichophycus pedum Assemblage Zone lies above the highest Ediacaran-type biotas (vendobionts, putative metazoans, and calcareous problematica such as Cloudina) and the basal Asteridium tornatum-Comasphaeridium velvetum Zone (acritarchs). This definition and the likely close correspondence of evolutionary origin and local FAD of T. pedum preserves the Fortune Head, Newfoundland, GSSP of the Cambrian base and allows the presence of sub-Cambrian, branched ichnofossils. The sub-Tommotian-equivalent base of Stage 2 (a suggested "Laolinian Stage") should be defined by the I'/L4/ZHUCE δ13C positive peak, bracketed by the lower ranges of Watsonella crosbyi and Aldanella attleborensis (molluscs) and the Skiagia ornata-Fimbrioglomerella membranacea Zone (acritarchs). The W. crosbyi and A. attleborensis FADs cannot define a Stage 2 base as they are diachronous even in the Newfoundland "type" W. crosbyi Zone. The Series 2 base cannot be based on a species' FAD owing to the provincialism of skeletalised metazoans in the Terreneuvian-Series 2 boundary interval and global heterochrony of the oldest trilobites. A Series 2 and Stage 3 (a suggested "Lenaldanian Series" and "Zhurinskyan Stage," new) GSSP base is proposed at the Siberian lower Atdabanian δ13C IV peak—which correlates into South China, Avalonia, and Morocco and assigns the oldest trilobites to the terminal Terreneuvian Series.
Andrzejak, Ralph G.; Hauf, Martinus; Pollo, Claudio; Müller, Markus; Weisstanner, Christian; Wiest, Roland; Schindler, Kaspar
2015-01-01
Background Epilepsy surgery is a potentially curative treatment option for pharmacoresistent patients. If non-invasive methods alone do not allow to delineate the epileptogenic brain areas the surgical candidates undergo long-term monitoring with intracranial EEG. Visual EEG analysis is then used to identify the seizure onset zone for targeted resection as a standard procedure. Methods Despite of its great potential to assess the epileptogenicty of brain tissue, quantitative EEG analysis has not yet found its way into routine clinical practice. To demonstrate that quantitative EEG may yield clinically highly relevant information we retrospectively investigated how post-operative seizure control is associated with four selected EEG measures evaluated in the resected brain tissue and the seizure onset zone. Importantly, the exact spatial location of the intracranial electrodes was determined by coregistration of pre-operative MRI and post-implantation CT and coregistration with post-resection MRI was used to delineate the extent of tissue resection. Using data-driven thresholding, quantitative EEG results were separated into normally contributing and salient channels. Results In patients with favorable post-surgical seizure control a significantly larger fraction of salient channels in three of the four quantitative EEG measures was resected than in patients with unfavorable outcome in terms of seizure control (median over the whole peri-ictal recordings). The same statistics revealed no association with post-operative seizure control when EEG channels contributing to the seizure onset zone were studied. Conclusions We conclude that quantitative EEG measures provide clinically relevant and objective markers of target tissue, which may be used to optimize epilepsy surgery. The finding that differentiation between favorable and unfavorable outcome was better for the fraction of salient values in the resected brain tissue than in the seizure onset zone is consistent with growing evidence that spatially extended networks might be more relevant for seizure generation, evolution and termination than a single highly localized brain region (i.e. a “focus”) where seizures start. PMID:26513359
Brillante, Luca; Martínez-Luscher, Johann; Yu, Runze; Plank, Cassandra M; Sanchez, Luis; Bates, Terrence L; Brenneman, Charles; Oberholster, Anita; Kurtural, S Kaan
2017-07-05
Plant water stress affects grape (Vitis vinifera L. cv. Cabernet Sauvignon) berry composition and is variable in space due to variations in the physical environment at the growing site. We monitored the natural variability of grapevine water stress by stem water potential (Ψ stem ) and leaf gas exchange in an equi-distant grid in a commercial vineyard. Spatial differences were measured and related to topographical variation by modeling. Geospatial analysis and clustering allowed researchers to differentiate the vineyard block into two distinct zones having severe and moderate water stress where it varied by 0.2 MPa. Differences in stem water potential affected stomatal conductance, net carbon assimilation, and intrinsic water use efficiency that were different in all measurement dates. The two zones were selectively sampled at harvest for measurements of berry chemistry. The water status zones did not affect berry mass or yield per vine. Significant difference in total soluble solids was observed (3.56 Brix), and in titratable acidity, thus indicating a direct effect of water stress on ripening acceleration. Berry skin flavonol and anthocyanin composition and concentration were measured by C18 reversed-phased high-performance liquid chromatography (HPLC). The anthocyanins were most affected by the two water stress zones. The dihydroxylated anthocyanins were more affected than trihydroxylated; therefore, the ratio of the two forms increased. Flavonols were different in total amounts, but hydroxylation patterns were not affected. Proanthocyanidin isolates were characterized by acid catalysis in the presence of excess phloroglucinol followed by reversed-phase HPLC. Proanthocyanidins showed the least significant difference, although (+)-catechin terminal subunits were important predictors in a partial least square model used to summarize the multivariate relationships, predicting Ψ stem or the management zone. The results provide fundamental information on vineyard water status to discriminate harvest or direction to vineyard operators to modify irrigation management to equilibrate berry composition at harvest.
NASA Astrophysics Data System (ADS)
Tsuji, Y.; Nakajima, J.; Kita, S.; Okada, T.; Matsuzawa, T.; Hasegawa, A.
2007-12-01
Three-dimensional heterogeneous structure beneath northeastern (NE) Japan has been investigated by previous studies and an inclined seismic low-velocity zone is imaged in the mantle wedge sub-parallel to the down-dip direction of the subducting slab (Zhao et al., 1992, Nakajima et al., 2001). However, the heterogeneous structure within the slab has not been well studied even though it is very important to understand the whole process of water transportation from the slab to the surface. Here we show a detailed 3D seismic velocity structure within the subducted Pacific slab around Japan and propose a water-transportation path from the slab to the mantle wedge. In this study, we estimated 3D velocity structure within the Pacific slab by the double-difference tomography (Zhang and Thurber, 2003). We divided the study area, from Hokkaido to Kanto, into 6 areas due to the limitation of memory and computation time. In each area, arrival-time data of 7,500-17,000 events recorded at 70-170 stations were used in the analysis. The total number of absolute travel-time data was about 140,000-312,000 for P wave and 123,000-268,000 for S wave, and differential data were about 736,000-1,920,000 for P wave and 644,000-1,488,000 for S wave. Horizontal and vertical grid separations are 10-25 km and 6.5 km, respectively. RMS residuals of travel times for P wave decreased from 0.23s to 0.09s and for S wave from 0.35s to 0.13s. The obtained results are as follows: (1) a remarkable low-Vs zone exists in the uppermost part of the subducting slab, (2) it extends down to a depth of about 80 km, (3) the termination of this low-Vs zone almost corresponds to the "seismic belt" recently detected in the upper plane of the double seismic zone (Kita et al.,2006; Hasegawa et al., 2007), (4) at depths deeper than 80 km, a low-Vs and high-Vp/Vs zone is apparently distributed in the mantle wedge, immediately above the slab crust. We consider that these features reflect water-transportation processes from the slab to the mantle wedge. A low- Vs zone in the uppermost part of the subducting slab corresponds to the hydrous oceanic crust since its absolute velocity is about 4.0 km/s, comparable to that expected for the oceanic crust (Hacker et al., 2003). Dehydration reactions occur in the oceanic crust as temperature and pressure increase, and a relatively large amount of water is released at depths of about 80-100 km. The water generated by dehydration reactions could migrate upward and react peridotite at the base of the mantle wedge, forming a thin-serpentine layer there. Then, the layer is dragged by the subducting slab to deeper depths (e.g. Iwamori, 1998). Such water-transportation processes from the slab to the mantle wedge are partly constrained by a recent receiver function analysis (Kawakatsu and Watada, 2007). We further found an along-arc variation of the termination depth of the low-velocity oceanic crust, suggesting the along-arc variation in the amount of fluids released from the slab.
Surface ocean carbon isotope anomalies on glacial terminations: An alternative view
NASA Astrophysics Data System (ADS)
Lund, D. C.; Cote, M.; Schmittner, A.
2016-12-01
Late Pleistocene glacial terminations are characterized by surface ocean carbon isotope minima on a global scale. During the last deglaciation (i.e. Termination 1), planktonic foraminiferal δ13C anomalies occurred in the Atlantic, Indian, Pacific, and Southern Oceans. Despite the apparently ubiquitous nature of δ13C anomalies on glacial terminations, their cause remains a matter of ongoing debate. The prevailing view is that isotopically light carbon from the abyss was upwelled in the Southern Ocean, resulting in outgassing of 13C-depleted carbon to the atmosphere and its advection to lower latitudes via mode and intermediate waters (Spero and Lea, 2002). Alternatively, carbon isotope minima may be driven by weakening of the biological pump related to circulation-driven changes in the oceanic preformed nutrient budget (Schmittner and Lund, 2015). Here we assess the deep upwelling and biological pump hypotheses using a new compilation of 70 globally-distributed planktonic δ13C records from the published literature. We find that 1) the mean deglacial δ13C anomaly is similar in all ocean basins, 2) the eastern tropical Pacific yields smaller mean δ13C anomalies than the western tropical Pacific, and 3) δ13C anomalies in the Southern Ocean decrease with increasing latitude. Our results are generally inconsistent with the deep upwelling hypothesis, which predicts that the δ13C signal should be largest in the Southern Ocean and upwelling regions. Instead, the spatial pattern in δ13C anomalies supports the biological pump hypothesis, which predicts that reduced export of light carbon from the euphotic zone triggers negative carbon isotope anomalies in the surface ocean and positive anomalies at intermediate depths. Upwelling of relatively 13C-enriched intermediate waters tends to moderate carbon isotope minima in upwelling regions. Our results suggest that the initial rise in atmospheric CO2 during Termination 1 was likely due to weakening of the biological pump associated with a reduction in the Atlantic Meridional Overturning Circulation, consistent with model results (Schmittner and Lund, 2015). Spero, H., and D. Lea (2002) Science 296, 522-525. Schmittner, A., and D. Lund (2015) Climate of the Past 11, 135-152.
Preliminary Hydrogeologic Characterization Results from the Wallula Basalt Pilot Study
DOE Office of Scientific and Technical Information (OSTI.GOV)
B.P. McGrail; E. C. Sullivan; F. A. Spane
2009-12-01
The DOE's Big Sky Regional Carbon Sequestration Partnership has completed drilling the first continental flood basalt sequestration pilot borehole to a total depth (TD) of 4,110 feet on the Boise White Paper Mill property at Wallula, Washington. Site suitability was assessed prior to drilling by the 2007-2008 acquisition, processing and analysis of a four-mile, five-line three component seismic swath, which was processed as a single data-dense line. Analysis of the seismic survey data indicated a composite basalt formation thickness of {approx}8,000 feet and absence of major geologic structures (i.e., faults) along the line imaged by the seismic swath. Drilling ofmore » Wallula pilot borehole was initiated on January 13, 2009 and reached TD on April 6, 2009. Based on characterization results obtained during drilling, three basalt breccia zones were identified between the depth interval of 2,716 and 2,910 feet, as being suitable injection reservoir for a subsequent CO2 injection pilot study. The targeted injection reservoir lies stratigraphically below the massive Umtanum Member of the Grande Ronde Basalt, whose flow-interior section possesses regionally recognized low-permeability characteristics. The identified composite injection zone reservoir provides a unique and attractive opportunity to scientifically study the reservoir behavior of three inter-connected reservoir intervals below primary and secondary caprock confining zones. Drill cuttings, wireline geophysical logs, and 31one-inch diameter rotary sidewall cores provided geologic data for characterization of rock properties. XRF analyses of selected rock samples provided geochemical characterizations of the rocks and stratigraphic control for the basalt flows encountered by the Wallula pilot borehole. Based on the geochemical results, the pilot borehole was terminated in the Wapshilla Ridge 1 flow of the Grande Ronde Basalt Formation. Detailed hydrologic test characterizations of 12 basalt interflow reservoir zones and 3 flow-interior/caprock intervals were performed during drilling and immediately following reaching the final borehole drilling depth (i.e., 4,110 ft). In addition, six of the 12 basalt interflow zones were selected for detailed hydrochemical characterization. Results from the detailed hydrologic test characterization program provided the primary information on basalt interflow zone transmissivity/injectivity, and caprock permeability characteristics.« less
Electrical conductivity of the Cascadia subduction zone and implications for the plate interface
NASA Astrophysics Data System (ADS)
Livelybrooks, D.; Bedrosian, P.; Egbert, G. D.; Key, K.; Schultz, A.; Parris, B. A.; Yang, B.; Bowles-martinez, E.
2016-12-01
The Magnetotelluric Observations of Cascadia using a Huge Array (MOCHA) experiment resulted in the collection of 146 amphibious, long-period magnetotelluric stations acquired between 2012 and 2014. These data, supplemented with the previously-acquired CAFÉ, EMSLAB, SWORMT and EarthScope (MT) Transportable Array stations, have been interpreted to provide electrical conductivity models of Cascadia spanning from the trench eastward through the Cascades, and extending to about 150km depth. We have a particular interest in understanding the roles electrically-conductive, aqueous fluids play in Cascadia subduction processes at or near the plate interface, thus inversions of data are predisposed to accommodate an initially-resistive (McCrory et al. 2014) slab. Beginning at the mantle wedge corner, 3-D inversions reveal significant, latitudinal variation in the conductivity, with enhanced conductivity at 47oN and south at 42oN. Two-dimensional inversions at 44.5oN allowing for a step discontinuity at the Moho give two distinct zones of conductance, one at the MWC tip (c.f. Furukowa, 2009) and another further down-dip, with a conductivity `plume' directed eastwards. At depths of between 20-25km we image a latitudinally-discontinuous resistive lower crust immediately overlying resistive subducted slab. This implies a lack of free fluids near the plate interface. Krogstad et al. (2016) have analyzed historic uplift data and can model the presence of an inboard `secondary locked zone' near 44.5oN. One explanation for both observations—a down-dip, `pinned interface' that is shielding the traditionally-modeled off-shore locked zone from stress accumulation, would explain the paucity of seismicity observed off the north-central Oregon coast during the four-year Cascadia Initiative. At coastal longitudes a narrow, supra-slab conductive zone is imaged at 22km depth with a southern termination at 45oN. It is notable that some researchers place the inboard boundary of the (mostly off-shore) seismogenic zone as moving eastward and on-shore beginning north of 45oN. The thinner Coast Range crust is imaged as generally more conductive north of 46oN, which is consistent with higher permeabilities ascribed to the Crescent formation.
Pohn, Howard A.
2000-01-01
Lateral ramps are zones where decollements change stratigraphic level along strike; they differ from frontal ramps, which are zones where decollements change stratigraphic level perpendicular to strike. In the Appalachian Mountains, the surface criteria for recognizing the subsurface presence of lateral ramps include (1) an abrupt change in wavelength or a termination of folds along strike, (2) a conspicuous change in the frequency of mapped faults or disturbed zones (extremely disrupted duplexes) at the surface, (3) long, straight river trends emerging onto the coastal plain or into the Appalachian Plateaus province, (4) major geomorphic discontinuities in the trend of the Blue Ridge province, (5) interruption of Mesozoic basins by cross-strike border faults, and (6) zones of modern and probable ancient seismic activity. Additional features related to lateral ramps include tectonic windows, cross-strike igneous intrusions, areas of giant landslides, and abrupt changes in Paleozoic sedimentation along strike. Proprietary strike-line seismic-reflection profiles cross three of the lateral ramps that were identified by using the surface criteria. The profiles confirm their presence and show their detailed nature in the subsurface. Like frontal ramps, lateral ramps are one of two possible consequences of fold-and-thrust-belt tectonics and are common elements in the Appalachian fold-and-thrust belt. A survey of other thrust belts in the United States and elsewhere strongly suggests that lateral ramps at depth can be identified by their surface effects. Lateral ramps probably are the result of thrust sheet motion caused by continued activation of ancient cratonic fracture systems. Such fractures localized the transform faults along which the continental segments adjusted during episodes of sea-floor spreading.
NASA Astrophysics Data System (ADS)
Halpaap, Felix; Rondenay, Stéphane; Ottemöller, Lars
2018-04-01
The Western Hellenic Subduction Zone is characterized by a transition from oceanic to continental subduction. In the southern oceanic portion of the system, abundant seismicity reaches depths of 100 km to 190 km, while the northern continental portion rarely exhibits deep earthquakes. Our study investigates how this oceanic-continental transition affects fluid release and related seismicity along strike. We present results from local earthquake tomography and double-difference relocation in conjunction with published images based on scattered teleseismic waves. Our tomographic images recover both subducting oceanic and continental crusts as low-velocity layers on top of high-velocity mantle. Although the northern and southern trenches are offset along the Kephalonia Transform Fault, continental and oceanic subducting crusts appear to align at depth. This suggests a smooth transition between slab retreat in the south and slab convergence in the north. Relocated hypocenters outline a single-planed Wadati-Benioff Zone with significant along-strike variability in the south. Seismicity terminates abruptly north of the Kephalonia Transform Fault, likely reflecting the transition from oceanic to continental subducted crust. Near 90 km depth, the low-velocity signature of the subducting crust fades out and the Wadati-Benioff Zone thins and steepens, marking the outline of the basalt-eclogite transition. Subarc melting of the mantle is only observed in the southernmost sector of the oceanic subduction, below the volcanic part of the arc. Beneath the nonvolcanic part, the overriding crust appears to have undergone large-scale silica enrichment. This enrichment is observed as an anomalously low Vp/Vs ratio and requires massive transport of dehydration-derived fluids updip through the subducting crust.
Proterozoic crustal boundary in the southern part of the Illinois Basin
Heigold, P.C.; Kolata, Dennis R.
1993-01-01
Recently acquired COCORP and proprietary seismic reflection data in the southern part of the Illinois Basin, combined with other geological and geophysical data, indicate that a WNW-trending Proterozoic terrane boundary (40 km wide) lies within basement. The boundary is characterized by the termination of subhorizontal Proterozoic reflectors and associated diffraction patterns along a line coinciding with the major magnetic lineament in this region (South Central Magnetic Lineament). North of the boundary, where reflectors thought to represent a sequence of layered Proterozoic rocks in the upper crust are widespread and as much as 11 km thick, total magnetic intensity values are relatively high, suggesting layers of rock with high magnetic susceptibility. To the south, the Proterozoic rocks are acoustically transparent on seismic reflection sections and total magnetic intensity values are relatively low. Moreover, relatively high Bouguer gravity anomaly values to the south may be caused by a dense, altered, lower crustal layer similar to that interpreted from deep seismic refraction studies to underlie the northern Mississippi Embayment. The boundary lies along the projected trend of the northern margin of the Early Proterozoic Central Plains orogen and we suggest that it marks the convergent margin of this orogen. Reactivation of the boundary and the associated zone of weakness during late Paleozoic times apparently resulted in structural deformation in the southern part of the Illinois Basin, including movement along the Cottage Grove Fault System and Ste. Genevieve Fault Zone and igneous activity at Hicks Dome. In addition to the role played by this crustal boundary in the evolution of the Illinois Basin, its location between the Wabash Valley Seismic Zone to the northeast and the New Madrid Seismic Zone to the southwest may be a significant factor in present-day seismicity. ?? 1993.
Winderl, Christian; Anneser, Bettina; Griebler, Christian; Meckenstock, Rainer U.; Lueders, Tillmann
2008-01-01
Microbial degradation is the only sustainable component of natural attenuation in contaminated groundwater environments, yet its controls, especially in anaerobic aquifers, are still poorly understood. Hence, putative spatial correlations between specific populations of key microbial players and the occurrence of respective degradation processes remain to be unraveled. We therefore characterized microbial community distribution across a high-resolution depth profile of a tar oil-impacted aquifer where benzene, toluene, ethylbenzene, and xylene (BTEX) degradation depends mainly on sulfate reduction. We conducted depth-resolved terminal restriction fragment length polymorphism fingerprinting and quantitative PCR of bacterial 16S rRNA and benzylsuccinate synthase genes (bssA) to quantify the distribution of total microbiota and specific anaerobic toluene degraders. We show that a highly specialized degrader community of microbes related to known deltaproteobacterial iron and sulfate reducers (Geobacter and Desulfocapsa spp.), as well as clostridial fermenters (Sedimentibacter spp.), resides within the biogeochemical gradient zone underneath the highly contaminated plume core. This zone, where BTEX compounds and sulfate—an important electron acceptor—meet, also harbors a surprisingly high abundance of the yet-unidentified anaerobic toluene degraders carrying the previously detected F1-cluster bssA genes (C. Winderl, S. Schaefer, and T. Lueders, Environ. Microbiol. 9:1035-1046, 2007). Our data suggest that this biogeochemical gradient zone is a hot spot of anaerobic toluene degradation. These findings show that the distribution of specific aquifer microbiota and degradation processes in contaminated aquifers are tightly coupled, which may be of value for the assessment and prediction of natural attenuation based on intrinsic aquifer microbiota. PMID:18083871
Matungulu, Charles Matungulu; Kandolo, Simon Ilunga; Mukengeshayi, Abel Ntambue; Nkola, Angèle Musau; Mpoyi, Dorcas Ilunga; Mumba, Sylvie Katanga; Kabamba, Julie Ndayi; Cowgill, Karen; Kaj, Françoise Malonga
2015-01-01
Introduction Augmenter la prévalence contraceptive s'incarne dans les objectifs des tous les acteurs des programmes qui visent de réduire la mortalité maternelle et infantile, d'améliorer la santé reproductive des adolescents, de lutter contre le VIH/SIDA et les infections sexuellement transmissible (IST), de promouvoir le bien-être familial et de ralentir la croissance démographique. L'objectif de cette étude était de déterminer la prévalence contraceptive moderne et identifier les facteurs qui sont liés à l'utilisation des méthodes contraceptives dans la zone de santé de Mumbunda. Méthodes Une étude transversale à visé analytique a été effectuée auprès des femmes âgées de 15 à 49 ans en union maritale, de Mai à Juin 2014. Grâce à un questionnaire pré testé et validé, nous avons récolté les données par interview sur les caractéristiques sociodémographiques, obstétricales ainsi que sur la pratique contraceptive. Le logiciel SPSS version 21 nous a permis d'analyser les données. Résultats Au total 500 femmes ont été incluses dans cette étude dont l’âge moyen était de 27,9±6,1 ans. La prévalence contraceptive moderne était de 27,6%. L'attitude (ORa= 4,79; IC95%: 1,59-14,43; p<0,001), le niveau de connaissance des méthodes contraceptives (ORa=1,87; IC95%: 1,22-2,87; p<0,001), le soutien du conjoint (ORa=1,87; IC95%: 1,22-2,87; p<0,001) étaient significativement associés à l'utilisation des méthodes contraceptives modernes. Conclusion Tout effort d'augmentation de la prévalence contraceptive devrait cibler l'attitude, le niveau de connaissance de méthodes et le soutien du conjoint afin d'optimiser l'utilisation de la contraception moderne dans la zone de santé (ZS) Mumbunda. PMID:26977237
Mechanisms of electron acceptor utilization: Implications for simulating anaerobic biodegradation
Schreiber, M.E.; Carey, G.R.; Feinstein, D.T.; Bahr, J.M.
2004-01-01
Simulation of biodegradation reactions within a reactive transport framework requires information on mechanisms of terminal electron acceptor processes (TEAPs). In initial modeling efforts, TEAPs were approximated as occurring sequentially, with the highest energy-yielding electron acceptors (e.g. oxygen) consumed before those that yield less energy (e.g., sulfate). Within this framework in a steady state plume, sequential electron acceptor utilization would theoretically produce methane at an organic-rich source and Fe(II) further downgradient, resulting in a limited zone of Fe(II) and methane overlap. However, contaminant plumes often display much more extensive zones of overlapping Fe(II) and methane. The extensive overlap could be caused by several abiotic and biotic processes including vertical mixing of byproducts in long-screened monitoring wells, adsorption of Fe(II) onto aquifer solids, or microscale heterogeneity in Fe(III) concentrations. Alternatively, the overlap could be due to simultaneous utilization of terminal electron acceptors. Because biodegradation rates are controlled by TEAPs, evaluating the mechanisms of electron acceptor utilization is critical for improving prediction of contaminant mass losses due to biodegradation. Using BioRedox-MT3DMS, a three-dimensional, multi-species reactive transport code, we simulated the current configurations of a BTEX plume and TEAP zones at a petroleum- contaminated field site in Wisconsin. Simulation results suggest that BTEX mass loss due to biodegradation is greatest under oxygen-reducing conditions, with smaller but similar contributions to mass loss from biodegradation under Fe(III)-reducing, sulfate-reducing, and methanogenic conditions. Results of sensitivity calculations document that BTEX losses due to biodegradation are most sensitive to the age of the plume, while the shape of the BTEX plume is most sensitive to effective porosity and rate constants for biodegradation under Fe(III)-reducing and methanogenic conditions. Using this transport model, we had limited success in simulating overlap of redox products using reasonable ranges of parameters within a strictly sequential electron acceptor utilization framework. Simulation results indicate that overlap of redox products cannot be accurately simulated using the constructed model, suggesting either that Fe(III) reduction and methanogenesis are occurring simultaneously in the source area, or that heterogeneities in Fe(III) concentration and/or mineral type cause the observed overlap. Additional field, experimental, and modeling studies will be needed to address these questions. ?? 2004 Elsevier B.V. All rights reserved.
Profil épidémiologique et clinique de la tuberculose dans la zone de santé de Lubumbashi (RD Congo)
Ngama, Christian Kakisingi; Muteya, Michel Manika; Lukusha, Yves Isango Idi; Kapend, Serge Matanda; Tshamba, Henri Mundongo; Makinko, Paul Ilunga; Mulumba, Claude Mwamba; Kalala, Liévin Kapend a
2014-01-01
Introduction L'objectif de notre travail était de déterminer la distribution sociodémographique des patients tuberculeux, les types de tuberculose en fonction de la localisation de la maladie et déterminer l'issue thérapeutique des patients en fonction de différentes localisations. Méthodes C'est une étude descriptive transversale des patients diagnostiqués et traités pour tuberculose du 1er Janvier 2010 au 30 Juin 2011 dans la zone de santé de Lubumbashi. Une de 11 zones de santé du District de Lubumbashi dans la province du Katanga(RD Congo). Ont été inclus tous les patients tuberculeux de nationalité congolaise consultés dans la zone de santé pendant la période d’étude. L’âge, le sexe, la commune de résidence, le tableau clinique à la première consultation et les résultats des examens de laboratoire des crachats par la coloration Ziehl-Neelsen ont été les paramètres d'analyse. Résultats Nous avons enregistré 708 patients tuberculeux soit une prévalence de 0.5%. Le sexe masculin représentait 58.78% contre 41.25% de sexe féminin avec un sexe ratio de 1.42 en faveur du sexe masculin. La moyenne d’âge était de 33±;15 ans. La majorité des patients soit 54.79 appartiennent à la tranche d’âge entre 21 et 40 ans. La tuberculose extra pulmonaire a représenté 51.8% contre 50.2% de tuberculose pulmonaire dont 31.9% à bacilloscopie positive. Le décès a intéressé les patients bacillifères puis qu'il y a 5 fois plus de décès liés à une tuberculose pulmonaire à microscopie positive qu'aux autres formes de tuberculose (OR (IC 95%): 5.27 (2.92-9.59, p = 0.00). La majorité des patients résidaient les communes Lubumbashi (41.7%) et Kampemba (23.2%). Conclusion La tuberculose extrapulmonaire (pleurale) a été plus rencontrée que la tuberculose pulmonaire et c'est cette dernière forme de tuberculose qui a entrainé beaucoup plus de décès. Ce qui nécessite une amélioration du système de santé de prise en charge des tuberculeux dans les démarches diagnostique, le suivi des patients bacilliformes et encourager l'adhérence au traitement. PMID:25018820
Cenozoic extensional tectonics of the Western Anatolia Extended Terrane, Turkey
NASA Astrophysics Data System (ADS)
Çemen, I.; Catlos, E. J.; Gogus, O.; Diniz, E.; Hancer, M.
2008-07-01
The Western Anatolia Extended Terrane in Turkey is located on the eastern side of the Aegean Extended Terrane and contains one of the largest metamorphic core complexes in the world, the Menderes massif. It has experienced a series of continental collisions from the Late Cretaceous to the Eocene during the formation of the Izmir-Ankara-Erzincan suture zone. Based our field work and monazite ages, we suggest that the north-directed postcollisional Cenozoic extension in the region is the product of three consecutive stages, triggered by three different mechanisms. The first stage was initiated about 30 Ma ago, in the Oligocene by the Orogenic Collapse the thermally weakened continental crust along the north-dipping Southwest Anatolian shear zone. The shear zone was formed as an extensional simple-shear zone with listric geometry at depth and exhibits predominantly normal-slip along its southwestern end. But, it becomes a high-angle oblique-slip shear zone along its northeastern termination. Evidence for the presence of the shear zone includes (1) the dominant top to the north-northeast shear sense indicators throughout the Menderes massif, such as stretching lineations trending N10E to N30E; and (2) a series of Oligocene extensional basins located adjacent to the shear zone that contain only carbonate and ophiolitic rock fragments, but no high grade metamorphic rock fragments. During this stage, erosion and extensional unroofing brought high-grade metamorphic rocks of the Central Menderes massif to the surface by the early Miocene. The second stage of the extension was triggered by subduction roll-back and associated back-arc extension in the early Miocene and produced the north-dipping Alaşehir and the south-dipping Büyük Menderes detachments of the central Menderes massif and the north-dipping Simav detachment of the northern Menderes massif. The detachments control the Miocene sedimentation in the Alaşehir, Büyük Menderes, and Simav grabens, containing high-grade metamorphic rock fragments. The third stage of the extension was triggered by the lateral extrusion (tectonic escape) of the Anatolian plate when the North Anatolian fault was initiated at about 5 Ma. This extensional phase produced the high-angle faults in the Alaşehir, Büyük Menderes and Simav grabens and the high-angle faults controlling the Küçük Menderes graben.
NASA Astrophysics Data System (ADS)
Cemen, I.; Catlos, E. J.; Diniz, E.; Gogus, O.; Ozerdem, C.; Baker, C.; Kohn, M. J.; Goncuoglu, C.; Hancer, M.
2006-12-01
The Western Anatolia Extended Terrane in Turkey is one of the best-developed examples of post-collisional extended terranes and contains one of the largest metamorphic core complexes in the world, the Menderes massif. It has experienced a series of continental collisions from the Late Cretaceous to the Eocene as the Neotethys Ocean closed and the Izmir-Ankara-Erzincan suture zone was formed. Based our field work and monazite ages, we suggest that the north-directed postcollisional Cenozoic extension in the region is the product of three consecutive, uninterrupted stages, triggered by three different mechanisms. The first stage was initiated about 30 Ma ago, in the Oligocene by the Orogenic Collapse the thermally weakened continental crust along the north-dipping Southwest Anatolian shear zone. The shear zone was formed as an extensional simple-shear zone with listric geometry at depth and exhibits predominantly normal- slip along its southwestern end. But, it becomes a high-angle oblique-slip shear zone along its northeastern termination. Evidence for the presence of the shear zone includes (1) the dominant top to the north-northeast shear sense indicators throughout the Menderes massif, such as stretching lineations trending N10E to N30E; and (2) a series of Oligocene extensional basins located adjacent to the shear zone that contain only carbonate and ophiolitic rock fragments, but no high grade metamorphic rock fragments. During this stage, erosion and extensional unroofing brought high-grade metamorphic rocks of the central Menderes massif to the surface by the early Miocene. The second stage of the extension was triggered by subduction roll-back and associated back-arc extension in the early Miocene and produced the north-dipping Alasehir and the south-dipping Buyuk Menderes detachments of the central Menderes massif and the north-dipping Simav detachment of the northern Menderes massif. The detachments control the Miocene sedimentation in the Alasehir, Buyuk Menderes, and Simav grabens, containing high-grade metamorphic rock fragments. The third stage of the extension was triggered by the lateral extrusion (tectonic escape) of the Anatolian plate when the North Anatolian fault was initiated at about 5 Ma. This extensional phase produced the high- angle faults in the Alasehir, Buyuk Menderes and Simav grabens and the high-angle faults controlling the Kucuk Menderes graben.
NASA Astrophysics Data System (ADS)
Willcock, M. A. W.; Cas, R. A. F.
2014-06-01
Exceptional exposure through a Permian intra-caldera ignimbrite fill within the 42 × 40 km Ora caldera (>1,290 km3 erupted volume) provides an opportunity to study welding textures in a thick intra-caldera ignimbrite succession. The ignimbrite succession records primary dense welding, a simple cooling unit structure, common crystallisation zones, and remarkably preserves fresh to slightly hydrated glass in local vitrophyre zones. Evidence for primary syn- and post-emplacement welding consists of (a) viscously deformed and sintered juvenile glass and relict shard textures; (b) complete deposit welding; (c) subtle internal welding intensity variations; (d) vitrophyre preserved locally at the base of the ignimbrite succession; (e) persistent fiamme juvenile clast shapes throughout the succession at the macroscopic and microscopic scales, defining a moderate to well-developed eutaxitic texture; (f) common undulating juvenile clast (pumice) margins and feathery terminations; (g) a general loss of deposit porosity; and (h) perlitic fracturing. A low collapsing or fountaining explosive eruption column model is proposed to have facilitated the ubiquitous welding of the deposit, which in turn helped preserve original textures. The ignimbrite succession preserves no evidence of a time break through the sequence and columnar joints cross-gradational ignimbrite lithofacies boundaries, so the ignimbrite is interpreted to represent a simple cooling unit. Aspect ratio and anisotropy of magnetic susceptibility (AMS) analyses through stratigraphic sections within the thick intra-caldera succession and at the caldera margin reveal variable welding compaction and strain profiles. Significantly, these data show that welding degree/intensity may vary in an apparently simple cooling unit because of variations in eruption process recorded in differing lithofacies. These data imply complex eruption, emplacement, and cooling processes. Three main crystallisation textural zones are identified in the ignimbrite succession: localised vitrophyre zones, widespread microcrystalline to sparsely spherulitic pseudomorphed vitriclastic textural zones, and thick granophyric zones. These zones record a typical spectrum from rapid to prolonged cooling. The non-uniform crystallisation patterns reflect variations in deposit thickness, the relative position of deposits within the larger ignimbrite succession, the type of substrate material, and the degree of confinement in the intra-caldera setting. We support previous work suggesting that traditional welding classifications (e.g. Smith, US Geological Survey Professional Paper 354-F 1960b) are most appropriate for use within altered and/or ancient ignimbrite successions.
Jackson, M B
1995-01-01
Based on functional characterizations with electrophysiological techniques, the channels in nerve terminals appear to be as diverse as channels in nerve cell bodies (Table I). While most presynaptic Ca2+ channels superficially resemble either N-type or L-type channels, variations in detail have necessitated the use of subscripts and other notations to indicate a nerve terminal-specific subtype (e.g., Wang et al., 1993). Variations such as these pose a serious obstacle to the identification of presynaptic channels based solely on the effects of channel blockers on synaptic transmission. Pharmacological sensitivity alone is not likely to help in determining functional properties. Crucial details, such as voltage sensitivity and inactivation, require direct examination. It goes without saying that every nerve terminal membrane contains Ca2+ channels as an entry pathway so that Ca2+ can trigger secretion. However, there appears to be no general specification of channel type, other than the exclusion of T-type Ca2+ channels. T-type Ca2+ channels are defined functionally by strong inactivation and low threshold. Some presynaptic Ca2+ channels inactivate (posterior pituitary and Xenopus nerve terminals), and others have a somewhat reduced voltage threshold (retinal bipolar neurons and squid giant synapse). Perhaps it is just a matter of time before a nerve terminal Ca2+ channel is found with both of these properties. The high threshold and strong inactivation of T-type Ca2+ channels are thought to be adaptations for oscillations and the regulation of bursting activity in nerve cell bodies. The nerve terminals thus far examined have no endogenous electrical activity, but rather are driven by the cell body. On functional grounds, it is then reasonable to anticipate finding T-type Ca2+ channels in nerve terminals that can generate electrical activity on their own. The rarity of such behavior in nerve terminals may be associated with the rarity of presynaptic T-type Ca2+ channels. In four of the five preparations reviewed in this chapter--motor nerve, squid giant synapse, ciliary ganglion, and retina bipolar neurons--evidence was presented that supports a location for Ca2+ channels that is very close to active zones of secretion. All of these synapses secrete from clear vesicles, and the speed and specificity of transduction provided by proximity may be a common feature of these rapid synapses. In contrast, the posterior pituitary secretion apparatus may be triggered by higher-affinity Ca2+ receptors and lower concentrations of Ca2+ (Lindau et al., 1992). This would correspond with the slower performance of peptidergic secretion, but because of the large stimuli needed to evoke release from neurosecretosomes, the possibility remains that the threshold for secretion is higher than that reported. While the role of Ca2+ as a trigger of secretion dictates a requirement for voltage-activated Ca2+ channels as universal components of the presynaptic membrane, the presence of other channels is more difficult to predict. Depolarizations caused by voltage-activated Na+ channels activate the presynaptic Ca2+ channels, but whether this depolarization requires Na+ channels in the presynaptic membrane itself may depend on the electrotonic length of the nerve terminal. Variations in density between motor nerve terminals may reflect species differences in geometry. The high Na+ channel density in the posterior pituitary reflects the great electrotonic length of this terminal arbor. Whether Na+ channels are abundant or not in a presynaptic membrane, K+ channels provide the most robust mechanism for limiting depolarization-induced Ca2+ entry. K+ channel blockers enhance transmission at most synapses. In general, K+ channels are abundant in nerve terminals, although their apparent lower priority compared to Ca2+ channels in the eyes of many investigators leaves us with fewer detailed investigations in some preparations. Most nerve terminals have more than
Spatiotemporal patterns of fault slip rates across the Central Sierra Nevada frontal fault zone
NASA Astrophysics Data System (ADS)
Rood, Dylan H.; Burbank, Douglas W.; Finkel, Robert C.
2011-01-01
Patterns in fault slip rates through time and space are examined across the transition from the Sierra Nevada to the Eastern California Shear Zone-Walker Lane belt. At each of four sites along the eastern Sierra Nevada frontal fault zone between 38 and 39° N latitude, geomorphic markers, such as glacial moraines and outwash terraces, are displaced by a suite of range-front normal faults. Using geomorphic mapping, surveying, and 10Be surface exposure dating, mean fault slip rates are defined, and by utilizing markers of different ages (generally, ~ 20 ka and ~ 150 ka), rates through time and interactions among multiple faults are examined over 10 4-10 5 year timescales. At each site for which data are available for the last ~ 150 ky, mean slip rates across the Sierra Nevada frontal fault zone have probably not varied by more than a factor of two over time spans equal to half of the total time interval (~ 20 ky and ~ 150 ky timescales): 0.3 ± 0.1 mm year - 1 (mode and 95% CI) at both Buckeye Creek in the Bridgeport basin and Sonora Junction; and 0.4 + 0.3/-0.1 mm year - 1 along the West Fork of the Carson River at Woodfords. Data permit rates that are relatively constant over the time scales examined. In contrast, slip rates are highly variable in space over the last ~ 20 ky. Slip rates decrease by a factor of 3-5 northward over a distance of ~ 20 km between the northern Mono Basin (1.3 + 0.6/-0.3 mm year - 1 at Lundy Canyon site) to the Bridgeport Basin (0.3 ± 0.1 mm year - 1 ). The 3-fold decrease in the slip rate on the Sierra Nevada frontal fault zone northward from Mono Basin is indicative of a change in the character of faulting north of the Mina Deflection as extension is transferred eastward onto normal faults between the Sierra Nevada and Walker Lane belt. A compilation of regional deformation rates reveals that the spatial pattern of extension rates changes along strike of the Eastern California Shear Zone-Walker Lane belt. South of the Mina Deflection, extension is accommodated within a diffuse zone of normal and oblique faults, with extension rates increasing northward on the Fish Lake Valley fault. Where faults of the Eastern California Shear Zone terminate northward into the Mina Deflection, extension rates increase northward along the Sierra Nevada frontal fault zone to ~ 0.7 mm year - 1 in northern Mono Basin. This spatial pattern suggests that extension is transferred from more easterly fault systems, e.g., Fish Lake Valley fault, and localized on the Sierra Nevada frontal fault zone as the Eastern California Shear Zone-Walker Lane belt faulting is transferred through the Mina Deflection.
STS-98 crew poses for photo after media briefing
NASA Technical Reports Server (NTRS)
2001-01-01
KENNEDY SPACE CENTER, Fla. -- After a media briefing at Launch Pad 39A, the STS-98 crew poses in the slidewire basket landing zone. Standing, left to right, are Pilot Mark Polansky, Mission Specialist Thomas Jones, Commander Ken Cockrell and Mission Specialists Marsha Ivins and Robert Curbeam. All are at KSC to take part in Terminal Countdown Demonstration Test activities, which include emergency egress training and a simulated launch countdown. STS-98 is the seventh construction flight to the International Space Station, carrying as payload the U.S. Lab Destiny, a key element in the construction of the ISS. Launch of STS-98 is scheduled for Jan. 19 at 2:11 a.m.
A 100-year average recurrence interval for the San Andreas fault at Wrightwood, California
Fumal, T.E.; Pezzopane, S.K.; Weldon, R.J.; Schwartz, D.P.
1993-01-01
Evidence for five large earthquakes during the past five centuries along the San Andreas fault zone 70 kilometers northeast of Los Angeles, California, indicates that the average recurrence interval and the temporal variability are significantly smaller than previously thought. Rapid sedimentation during the past 5000 years in a 150-meter-wide structural depression has produced a greater than 21-meter-thick sequence of debris flow and stream deposits interbedded with more than 50 datable peat layers. Fault scarps, colluvial wedges, fissure infills, upward termination of ruptures, and tilted and folded deposits above listric faults provide evidence for large earthquakes that occurred in A.D. 1857, 1812, and about 1700, 1610, and 1470.
2012-10-16
PORT CANAVERAL, Fla. – Col. Rory Welch, vice commander for the 45th Space Wing at Patrick Air Force Base, spoke during opening ceremonies at the Historically Underutilized Business Zone, or HUBZone, Industry Day and Expo 2012. The event was hosted for business leaders who are interested in learning about government contracting opportunities and what local and national vendors have to offer. The expo was held in Cruise Terminal 4 at Port Canaveral, Fla. The annual trade show is sponsored by Kennedy's Prime Contractor Board, the U.S. Air Force 45th Space Wing and the Canaveral Port Authority. It featured about 175 large and small businesses and government exhibitors from Brevard County and across the nation. Photo credit: NASA/ Kim Shiflett
2012-10-16
PORT CANAVERAL, Fla. – Greg Weiner, senior director of Business Development for the Economic Development Commission of Florida’s Space Coast, spoke during opening ceremonies at the Historically Underutilized Business Zone, or HUBZone, Industry Day and Expo 2012. The event was hosted for business leaders who are interested in learning about government contracting opportunities and what local and national vendors have to offer. The expo was held in Cruise Terminal 4 at Port Canaveral, Fla. The annual trade show is sponsored by Kennedy's Prime Contractor Board, the U.S. Air Force 45th Space Wing and the Canaveral Port Authority. It featured about 175 large and small businesses and government exhibitors from Brevard County and across the nation. Photo credit: NASA/ Kim Shiflett
2012-10-16
PORT CANAVERAL, Fla. – Glenn Delgado, NASA associate administrator for the Office of Small Business Programs, spoke during opening ceremonies at the Historically Underutilized Business Zone, or HUBZone, Industry Day and Expo 2012. The event was hosted for business leaders who are interested in learning about government contracting opportunities and what local and national vendors have to offer. The expo was held in Cruise Terminal 4 at Port Canaveral, Fla. The annual trade show is sponsored by Kennedy's Prime Contractor Board, the U.S. Air Force 45th Space Wing and the Canaveral Port Authority. It featured about 175 large and small businesses and government exhibitors from Brevard County and across the nation. Photo credit: NASA/ Kim Shiflett
2012-10-16
PORT CANAVERAL, Fla. – Larry Third, NASA small business specialist at the Kennedy Space Center in Florida, spoke during opening ceremonies at the Historically Underutilized Business Zone, or HUBZone, Industry Day and Expo 2012. The event was hosted for business leaders who are interested in learning about government contracting opportunities and what local and national vendors have to offer. The expo was held in Cruise Terminal 4 at Port Canaveral, Fla. The annual trade show is sponsored by Kennedy's Prime Contractor Board, the U.S. Air Force 45th Space Wing and the Canaveral Port Authority. It featured about 175 large and small businesses and government exhibitors from Brevard County and across the nation. Photo credit: NASA/ Kim Shiflett
2012-10-16
PORT CANAVERAL, Fla. – Larry Third, NASA small business specialist at the Kennedy Space Center in Florida, spoke during opening ceremonies at the Historically Underutilized Business Zone, or HUBZone, Industry Day and Expo 2012. The event was hosted for business leaders who are interested in learning about government contracting opportunities and what local and national vendors have to offer. The expo was held in Cruise Terminal 4 at Port Canaveral, Fla. The annual trade show is sponsored by Kennedy's Prime Contractor Board, the U.S. Air Force 45th Space Wing and the Canaveral Port Authority. It featured about 175 large and small businesses and government exhibitors from Brevard County and across the nation. Photo credit: NASA/ Kim Shiflett
NASA Astrophysics Data System (ADS)
Cheng, Jianmei; Chen, Chongxi; Ji, Menrui
The main task of studies on salt-water intrusion into coastal confined aquifers is to predict the position of the fresh- salt-water interface, which can be determined from the length of the aquifer roof extending under the sea. Records of groundwater level affected by tides can be used to infer hydrological conditions and determine hydraulic parameters of an aquifer extending under the sea. In this paper, a three-dimensional, variable-density groundwater flow model has been developed to determine the equivalent roof length of an aquifer extending under the sea from the tidal-effected data of groundwater level in the Jahe River Basin, Shandong Province, China. The seaward boundary is obtained by converging hydraulic head fluctuations observed in drill holes with calculated values, and the aquifer parameters in the extending zone are estimated. The impacts of aquifer roof length and aquifer parameters on the fluctuation of tidal groundwater are studied. It is concluded that the length of the aquifer roof extending under the sea should correspond with certain aquifer parameters in the extrapolation zone. Therefore, the seaward boundary determined from tidal-effect information is the equivalent boundary in hydrodynamic characteristics rather than the true boundary of the confined aquifer Les sujets principaux des études d'instrusion saline dans les aquifères confinés en zone côtière sont la prédiction de la position de l'interface entre l'eau salée et l'eau fraîche, qui peut être déterminée à partir de l'extention du toit de l'aquifère sous la mer. Les enregistrements des niveaux des eaux souterraines influencés par les marées peuvent être utilisés pour préciser les conditions hydrologiques et déterminer les paramètres hydrauliques d'un aquifère possédant une extension sous la mer. Dans cet article, un modèle tridimensionnel comprenant des eaux souterraines de densité variable a été développé pour déterminer la longueur équivalente du toit d'un aquifère qui s'étend sous la mer à partir des données concernant les effets de marée sur les eaux souterraines dans le bassin de la rivière Jahe, dans la province de Shandong, Chine. La limite de salinité est déterminée en faisant converger les fluctuations des hauteurs piézométriques avec les valeurs calculées, et les paramètres de l'aquifère sont estimés dans la zone s'étendant sous la mer. L'incidence de la longueur de l'aquifère sous la mer sur les fluctuations des niveaux est étudiée. On en conclut que la longueur du toit de l'aquifère sous la mer peut correspondre à certains aquifères paramètres dans la zone d'extrapolation. Par conséquent, la limite de salinité déterminée à partir des effets de marée est l'équivalent d'une limite hydrodynamique plutôt que la véritable limite de l'aquifère. El principal objetivo de los estudios sobre intrusiones de agua salada en acuíferos costeros confinados es predecir la posición de la interfase agua dulce-agua salada, la cual puede determinarse a partir de la longitud del techo del acuífero que se extiende por debajo del mar. Los registros de niveles de agua subterránea afectados por las mareas puede utilizarse para inferir las condiciones hidrológicas y determinar los parámetros hidráulicos de un acuífero que se extiende por debajo del mar. En este artículo se ha desarrollado un modelo de flujo tri-dimensional de agua subterránea de densidad variable para determinar la longitud del techo equivalente de un acuífero que se extiende por debajo del mar a partir de datos, afectados por la marea, de niveles de agua subterránea en la Cuenca del Río Jahe, Provincia Shandong, China. El límite hacia el océano se obtiene por convergencia de fluctuaciones de presiones hidráulicas observadas en pozos con valores calculados, y se estiman los parámetros del acuífero en la zona extendida. Se estudian los impactos de la longitud del techo del acuífero y los parámetros del acuífero en la fluctuación del agua subterránea afectada por las mareas. Se concluye que la longitud del techo del acuífero que se extiende por debajo del mar debería corresponder con ciertos parámetros del acuífero en la zona de extrapolación. Por lo tanto, el límite hacia el océano determinado a partir de información de efectos de marea es el límite equivalente en características hidrodinámicas más que el límite real del acuífero confinado.
NASA Astrophysics Data System (ADS)
Basili, R.; Langridge, R. M.; Villamor, P.; Rieser, U.
2008-12-01
The Poukawa Fault Zone is one component of a complex system of contractional faulting in eastern North Island, New Zealand. It is located within the actively uplifting Hikurangi Margin where the Australian plate meets the Pacific plate at a convergence rate of over 40 mm/yr. The most destructive earthquake in New Zealand history, the 1931 Hawke's Bay earthquake of M 7.8, occurred just off the northern termination of the Poukawa Fault Zone. To the south and probably within the Poukawa Fault Zone, another strong earthquake struck near Waipukurau in 1863. We have characterized the contemporary style of faulting along the zone on the basis of an integrated analysis of a broad spectrum of data, including exploratory trenching; geomorphic data aided by 1m resolution digital orthophotos, a LIDAR-derived Terrain Model, and GPS-RTK surveys; stratigraphic and paleoseismic analysis; radiocarbon and OSL dating and tephra correlation. We have also made a detailed reconstruction of the terrace sequences formed where the Kaikora Stream crosses at a high angle to the Poukawa Fault Zone. These data show that the Poukawa Fault Zone is a contractional fault system formed by a series of NE-SW strands with style varying, from west to east, from high-angle east-dipping reverse to low-angle west-dipping thrusting. The geometry of the system suggests that these faults may merge at shallow depth into a single large structure capable of generating strong earthquakes similar to those that occurred in the past on nearby sections. All these faults variously displace the top of the Ohakean aggradation surface (12-15 ka) thereby generating scarps of several meters. The Kaikora Stream terrace sequences also testify to a series of uplift events associated with the late-Holocene growth of two of the eastern thrust faults. Two reaches of Kaikora Stream show evidence of uplifted and abandoned inset Holocene stream terraces found in association with a surface-rupture trace and an active fold. The four terraces in each case correspond in number with paeloearthquake events recognized in trenches nearby (Kelsey et al. 1998). Based on these relations the recurrence interval of surface faulting and folding is c. 3000-3700 yr. The abandonment of a low inset terrace capped by peat and Waimihia Tephra (c. 3400 yr BP) is consistent with this average recurrence. Based on the deformation of the dated Ohakean surface across the entire Poukawa Fault Zone, its reverse slip rate is c. 1-2 mm/yr.
The radiation from slots in truncated dielectric-covered surfaces
NASA Technical Reports Server (NTRS)
Hwang, Y. M.; Kouyoumjian, R. G.; Pathak, P. H.
1974-01-01
A theoretical approach based on the geometrical theory of diffraction is used to study the electromagnetic radiation from a narrow slot in a dielectric-covered perfectly-conducting surface terminated at an edge. The total far-zone field is composed of a geometrical optics field and a diffracted field. The geometrical optics field is the direct radiation from the slot to the field point. The slot also generates surface waves which are incident at the termination of the dielectric cover, where singly-diffracted rays and reflected surface waves are excited. The diffraction and reflection coefficients are obtained from the canonical problem of the diffraction of a surface wave by a right-angle wedge where the dielectric-covered surface is approximated by an impedance surface. This approximation is satisfactory for a very thin cover; however, the radiation from its vertical and faces cannot be neglected in treating the thicker dielectric cover. This is taken into account by using a Kirchhoff-type approximation, which contributes a second term to the diffraction coefficient previously obtained. The contributions from the geometrical optics field, the singly-diffracted rays and all significant multiply-diffracted rays are summed to give the total radiation. Calculated and measured patterns are found to be in good agreement.
Seismotectonics and Crustal Thickness of Northwest Mindoro, Philippines
NASA Astrophysics Data System (ADS)
Chen, P. F.; Olavere, E. A.; Lee, K. M.; Bautista, B.; Solidum, R., Jr.; Huang, B. S.
2015-12-01
Mindoro Island locates where the Palawan Continental Block (PCB) indented into the Philippine Mobile Belt (PMB) during the Early Miocene and where the Manila Trench terminates, having ceased convergence due to collision. On the transition from subduction to collision, Northwest Mindoro exhibits vigorous seismic activity and has been debated about its affiliation being PCB or PMB. Here, we use data from both the EHB and Global Centroid Moment Tensor catalogues to study the regional seismotectonics. We also deployed five broadband stations to probe the crustal thickness beneath NW Mindoro using receiver function analysis. Results show that, following the southeasterly reduction of convergence rates at the southern termination of the Manila Trench, the slab dipping angles steepen, were initiated at depth (~200 km) and propagate upwards. The horizontal distances of the trench and slab, as measured from the Wadati-Benioff zone at 200 km depth, also reduce in a southeasterly direction. Observations of intermediate-depth earthquakes that exhibit predominantly down-dip extensional stress patterns attest that the steepening of slab dipping angles is due to the negative buoyancy of the slab. Preliminary results of receiver function analysis suggest that the crustal thickness beneath NW Mindoro is about 40 km and is probably PCB affiliated.
The flowering hormone florigen functions as a general systemic regulator of growth and termination
Shalit, Akiva; Rozman, Alexander; Goldshmidt, Alexander; Alvarez, John P.; Bowman, John L.; Eshed, Yuval; Lifschitz, Eliezer
2009-01-01
The florigen paradigm implies a universal flowering-inducing hormone that is common to all flowering plants. Recent work identified FT orthologues as originators of florigen and their polypeptides as the likely systemic agent. However, the developmental processes targeted by florigen remained unknown. Here we identify local balances between SINGLE FLOWER TRUSS (SFT), the tomato precursor of florigen, and SELF-PRUNING (SP), a potent SFT-dependent SFT inhibitor as prime targets of mobile florigen. The graft-transmissible impacts of florigen on organ-specific traits in perennial tomato show that in addition to import by shoot apical meristems, florigen is imported by organs in which SFT is already expressed. By modulating local SFT/SP balances, florigen confers differential flowering responses of primary and secondary apical meristems, regulates the reiterative growth and termination cycles typical of perennial plants, accelerates leaf maturation, and influences the complexity of compound leaves, the growth of stems and the formation of abscission zones. Florigen is thus established as a plant protein functioning as a general growth hormone. Developmental interactions and a phylogenetic analysis suggest that the SFT/SP regulatory hierarchy is a recent evolutionary innovation unique to flowering plants. PMID:19416824
Takaku, Hiroaki; Kimoto, Ayumi; Kodaira, Shoko; Nashimoto, Masayuki; Takagi, Masamichi
2006-11-01
A Gram-positive poly(3-hydroxybutyrate) (PHB)-degrading bacterial strain was isolated from compost. This organism, identified as Bacillus megaterium N-18-25-9, produced a clearing zone on opaque NB-PHB agar, indicating the presence of extracellular PHB depolymerase. A PHB depolymerase gene, PhaZ(Bm), of B. megaterium N-18-25-9 was cloned and sequenced, and the recombinant gene product was purified from Escherichia coli. The N-terminal half region of PhaZ(Bm) shared significant homologies with a catalytic domain of other PHB depolymerases. Although the C-terminal half region of PhaZ(Bm) showed no significant similarity with those of other PHB depolymerases, that region was necessary for the PHB depolymerase activity. Therefore, this enzyme's domain structure is unique among extracellular PHB depolymerase domain structures. The addition of PHB to the medium led to a sixfold increase in PhaZ(Bm) mRNA, while the presence of glucose repressed PhaZ(Bm) expression. The maximum activity was observed at pH 9.0 at 65 degrees C.
Autonomous Flight Safety System
NASA Technical Reports Server (NTRS)
Ferrell, Bob; Santuro, Steve; Simpson, James; Zoerner, Roger; Bull, Barton; Lanzi, Jim
2004-01-01
Autonomous Flight Safety System (AFSS) is an independent flight safety system designed for small to medium sized expendable launch vehicles launching from or needing range safety protection while overlying relatively remote locations. AFSS replaces the need for a man-in-the-loop to make decisions for flight termination. AFSS could also serve as the prototype for an autonomous manned flight crew escape advisory system. AFSS utilizes onboard sensors and processors to emulate the human decision-making process using rule-based software logic and can dramatically reduce safety response time during critical launch phases. The Range Safety flight path nominal trajectory, its deviation allowances, limit zones and other flight safety rules are stored in the onboard computers. Position, velocity and attitude data obtained from onboard global positioning system (GPS) and inertial navigation system (INS) sensors are compared with these rules to determine the appropriate action to ensure that people and property are not jeopardized. The final system will be fully redundant and independent with multiple processors, sensors, and dead man switches to prevent inadvertent flight termination. AFSS is currently in Phase III which includes updated algorithms, integrated GPS/INS sensors, large scale simulation testing and initial aircraft flight testing.
NASA Astrophysics Data System (ADS)
Moldovan, Iren-Adelina; Oikonomou, Christina; Haralambous, Haris; Nastase, Eduard; Emilian Toader, Victorin; Biagi, Pier Francesco; Colella, Roberto; Toma-Danila, Dragos
2017-04-01
Ionospheric TEC (Total Electron Content) variations and Low Frequency (LF) signal amplitude data prior to five moderate earthquakes (Mw≥5) occurred in Romania, in Vrancea crustal and subcrustal seismic zones, during the last decade were analyzed using observations from the Global Navigation Satellite System (GNSS) and the European INFREP (International Network for Frontier Research on Earthquake Precursors) networks respectively, aiming to detect potential ionospheric anomalies related to these events and describe their characteristics. For this, spectral analysis on TEC data and terminator time method on VLF/LF data were applied. It was found that TEC perturbations appeared few days (1-7) up to few hours before the events lasting around 2-3 hours, with periods 20 and 3-5 minutes which could be associated with the impending earthquakes. In addition, in all three events the sunrise terminator times were delayed approximately 20-40 min few days prior and during the earthquake day. Acknowledgments This work was partially supported by the Partnership in Priority Areas Program - PNII, under MEN-UEFISCDI, DARING Project no. 69/2014 and the Nucleu Program - PN 16-35, Project no. 03 01
A plutonic view of explosive volcanism: the shatter zone of the Cadillac Mountain granite, Maine
NASA Astrophysics Data System (ADS)
Wiebe, R.
2013-12-01
The Silurian Cadillac Mountain granite (CMG) is about 15 km in diameter. It is underlain on its deeper western margin by layered gabbro-diorite (GD) up to 3 km thick and on its eastern and southern margins by an intrusive breccia (the 'shatter zone' (SZ)), up to 1 km wide. Coeval rhyolite tuffs, ignimbrites and lavas occur near the southern margin of the granite. The more shallow eastern part of the SZ can be divided into three zones: (SZA) An outer zone against country rock (CR) consists of strongly broken up, deformed sedimentary rocks and angular blocks of diabase invaded by thin irregular veins of aphanitic felsite. All CR fragments are tightly packed with less than ~ 15% matrix, which coarsens inward to vfg quartz, feldspar and biotite. (SZB) A central zone contains abundant sedimentary and scarce rhyolite blocks (typically < 1 m) and larger diabase blocks (from < 1 m to 10s of meters). This zone has 20 to 60% fg to mg matrix with quartz, two feldspars, biotite and abundant pieces of CR down to a few mm. It typically has a strong flow fabric around CR blocks. (SZC) The inner zone has only large (10-80 m) blocks of sedimentary rock, diabase and rhyolite (flows and ignimbrite). The mg granitic matrix (>60%) has blocky hypersolvus feldspar, interstitial to equant quartz, Fe-cpx, Fe-hornblende, two oxides and scarce fayalite. Feldspar in this zone consistently has a sequence of zones consisting of: (1) a homogeneous core of ~ An10Ab80Or10, (2) a transition up to 1 mm wide with 10-15 Or-Ab oscillations (e.g. from Or10 to Or30), each from 20 to 100 microns in width, and (3) a nearly homogeneous rim of variable width averaging about An3Ab70Or27. The occurrence of crystals with such distinctive zoning over such a great distance (18 km) suggests that the zoning was produced by an intensive parameter and not by magma mixing. Because the crystals are restricted to the SZ matrix, processes that produced the shatter zone probably also influenced feldspar zoning. Analysis of clast size distribution of CR fragments in SZA and SZB suggests an extremely high-energy environment consistent with a pyroclastic eruption from the CMG magma chamber (Roy et al. 2012). If such an eruption did occur, one expected effect would be episodic, sudden drops in pressure during degassing and eruptive events. Since the lower part of the chamber was apparently relatively dry (hypersolvus alkali feldspar with ternary feldspar occurs in CMG immediately above the GD), the drop in pressure would lower H2O activity so that the Ab-rich loop of the alkali feldspar phase diagram would shift to higher T, causing the melt to fall below the liquidus and shift the equilibrium solid feldspar to higher Or values. This matches the initial oscillatory zone to higher Or on the homogeneous cores. Because the SZ terminates at the top of the GD, it is likely that mafic input contributed to the eruption. The large inward increase in the crystallization T of the matrix from SZA to SZC probably records initial escape of a cooler felsic cap and upwelling of deep, hot hypersolvus magma along with partial collapse of the chamber roof.
Terminator 2020: Get Ready for the "Event" of The Next Decade
NASA Astrophysics Data System (ADS)
McIntosh, S. W.; Leamon, R. J.; Fan, Y.; Rempel, M.; Dikpati, M.
2017-12-01
The abrupt end of solar activity cycles 22 and 23 at the Sun's equator are observed with instruments from the Solar and Heliospheric Observatory (SOHO), Solar Terrestrial Relations Observatory (STEREO), and Solar Dynamics Observatory (SDO). These events are remarkable in that they rapidly trigger the onset of magnetic activity belonging to the next solar cycle at mid-latitudes. The triggered onset of new cycle flux emergence leads to blossoming of the new cycle shortly thereafter. Using small-scale tracers of magnetic solar activity we examine the timing of the cycle ``termination points'' in relation to the excitation of new activity and find that the time taken for the solar plasma to communicate this transition is less than one solar rotation, and possibly as little as a eight days. This very short transition time implies that the mean magnetic field present in the Sun's convection zone is approximately 80 kG. This value may be considerably larger than conventional explorations estimate and therefore, have a significant dynamical impact on the physical appearance of solar activity, and considerably impacting our ability to perform first-principles numerical simulations of the same. Should solar cycle 24 [and 25] continue in their progression we anticipate that a termination event of this type should occur in the 2020 timeframe. PSP will have a front row seat to observe this systemic flip in solar magnetism and the induced changes in our star's radiative and partiuculate output. Such observations may prove to be critical in assessing the Sun's ability to force short term evolution in the Earth's atmosphere.
Schoels, Wolfgang; Steinhaus, David; Johnson, W Ben; O'hara, Gilles; Schwab, Joerg O; Jenniskens, Inge; Degroot, Paul J; Tang, Feng; Helmling, Erhard
2007-07-01
Previous studies in implantable cardioverter-defibrillator (ICD) patients demonstrated the efficacy and safety of antitachycardia pacing (ATP) for rapid ventricular tachycardias (VT). To prevent shock delay in case of ATP failure, a new feature (ATP during charging) was developed to deliver ATP for rapid VT while charging for shock. The purpose of this study was to determine the efficacy and safety of this new feature. In a prospective, nonrandomized trial, patients with standard ICD indication received an EnTrust ICD. VT and ventricular fibrillation (VF) episodes were reviewed for appropriate detection, ATP success, rhythm acceleration, and related symptoms. In 421 implanted patients, 116 VF episodes occurred in 37 patients. Eighty-four (72%) episodes received ATP during or before charging. ATP prevented a shock in 58 (69%) of 84 episodes in 15 patients. ATP stopped significantly more monomorphic (77%) than polymorphic VTs (44%, P = .05). Five (6%) episodes accelerated after ATP but were terminated by the backup shock(s). No symptoms were related to ATP during charging. In four patients, 38 charges were saved by delivering ATP before charging. Of 98 induced VF episodes, 28% were successfully terminated by ATP versus 69% for spontaneous episodes (P <.01). Most VTs detected in the VF zone can be painlessly terminated by ATP delivered during charging, with a low risk of acceleration or symptoms. ATP before charging allows delivery of two ATP attempts before shock in the same time that would otherwise be required to deliver only one ATP plus a shock. It also offers potential battery energy savings.
Daniilidis, Aggelos; Balaouras, Dimitrios; Chitzios, Dimitrios; Balaouras, Georgios; Capilna, Mihai; Asimakopoulos, Efstratios
2015-01-01
Increased nuchal translucency (NT) is present in about 50% of cases with trisomy 21. Very often the nuchal edema evolves in hydrops fetalis until the second trimester. Furthermore, a small amount of cases with a normal NT and trisomy 21 exhibit anatomical anomalies. We present a case of a 21-year-old woman, nulliparous, with a history of one termination of pregnancy and a smoking quitter. The prenatal control was negative for TORCH. During the first trimester scan on the 13th week, the NT was found 2.7 mm, the ductus venosus Doppler was normal, and the nasal bone was present. Hydrops fetalis was present though, and the parents were advised for chorionic villus sampling (CVS), but they opted for termination of pregnancy. The molecular control by QF-PCR showed normal karyotype for 13 and 18, a male fetus, but non-dysjunction trisomy 21 was present. Parental karyotype was advised, but they refused to perform it. One year later, the couple had another pregnancy. On the 12th week scan, the NT was found 1.0 mm, the ductus venosus Doppler was normal, and the nasal bone was present, but encephalocele was also found, and the parents consented again for termination of pregnancy. The new molecular control showed the same results. This time parental karyotype was performed. The father had a normal one, whereas the mother showed reversed p11 and q13 zones in chromosome 2. Genetical consulting and prenatal cytological control was advised in before next pregnancy. PMID:25883716
Ghashghaei, H T; Hilgetag, C C; Barbas, H
2007-02-01
The prefrontal cortex and the amygdala have synergistic roles in regulating purposive behavior, effected through bidirectional pathways. Here we investigated the largely unknown extent and laminar relationship of prefrontal input-output zones linked with the amygdala using neural tracers injected in the amygdala in rhesus monkeys. Prefrontal areas varied vastly in their connections with the amygdala, with the densest connections found in posterior orbitofrontal and posterior medial cortices, and the sparsest in anterior lateral prefrontal areas, especially area 10. Prefrontal projection neurons directed to the amygdala originated in layer 5, but significant numbers were also found in layers 2 and 3 in posterior medial and orbitofrontal cortices. Amygdalar axonal terminations in prefrontal cortex were most frequently distributed in bilaminar bands in the superficial and deep layers, by columns spanning the entire cortical depth, and less frequently as small patches centered in the superficial or deep layers. Heavy terminations in layers 1-2 overlapped with calbindin-positive inhibitory neurons. A comparison of the relationship of input to output projections revealed that among the most heavily connected cortices, cingulate areas 25 and 24 issued comparatively more projections to the amygdala than they received, whereas caudal orbitofrontal areas were more receivers than senders. Further, there was a significant relationship between the proportion of 'feedforward' cortical projections from layers 2-3 to 'feedback' terminations innervating the superficial layers of prefrontal cortices. These findings indicate that the connections between prefrontal cortices and the amygdala follow similar patterns as corticocortical connections, and by analogy suggest pathways underlying the sequence of information processing for emotions.
NASA Astrophysics Data System (ADS)
Kelsey, Harvey M.; Ladinsky, Tyler C.; Staisch, Lydia; Sherrod, Brian L.; Blakely, Richard J.; Pratt, Thomas L.; Stephenson, William J.; Odum, Jack K.; Wan, Elmira
2017-10-01
The Yakima folds of central Washington, USA, are prominent anticlines that are the primary tectonic features of the backarc of the northern Cascadia subduction zone. What accounts for their topographic expression and how much strain do they accommodate and over what time period? We investigate Manastash anticline, a north vergent fault propagation fold typical of structures in the fold province. From retrodeformation of line- and area-balanced cross sections, the crust has horizontally shortened by 11% (0.8-0.9 km). The fold, and by inference all other folds in the fold province, formed no earlier than 15.6 Ma as they developed on a landscape that was reset to negligible relief following voluminous outpouring of Grande Ronde Basalt. Deformation is accommodated on two fault sets including west-northwest striking frontal thrust faults and shorter north to northeast striking faults. The frontal thrust fault system is active with late Quaternary scarps at the base of the range front. The fault-cored Manastash anticline terminates to the east at the Naneum anticline and fault; activity on the north trending Naneum structures predates emplacement of the Grande Ronde Basalt. The west trending Yakima folds and west striking thrust faults, the shorter north to northeast striking faults, and the Naneum fault together constitute the tectonic structures that accommodate deformation in the low strain rate environment in the backarc of the Cascadia Subduction Zone.
Anatomy of the western Java plate interface from depth-migrated seismic images
NASA Astrophysics Data System (ADS)
Kopp, H.; Hindle, D.; Klaeschen, D.; Oncken, O.; Reichert, C.; Scholl, D.
2009-11-01
Newly pre-stack depth-migrated seismic images resolve the structural details of the western Java forearc and plate interface. The structural segmentation of the forearc into discrete mechanical domains correlates with distinct deformation styles. Approximately 2/3 of the trench sediment fill is detached and incorporated into frontal prism imbricates, while the floor sequence is underthrust beneath the décollement. Western Java, however, differs markedly from margins such as Nankai or Barbados, where a uniform, continuous décollement reflector has been imaged. In our study area, the plate interface reveals a spatially irregular, nonlinear pattern characterized by the morphological relief of subducted seamounts and thicker than average patches of underthrust sediment. The underthrust sediment is associated with a low velocity zone as determined from wide-angle data. Active underplating is not resolved, but likely contributes to the uplift of the large bivergent wedge that constitutes the forearc high. Our profile is located 100 km west of the 2006 Java tsunami earthquake. The heterogeneous décollement zone regulates the friction behavior of the shallow subduction environment where the earthquake occurred. The alternating pattern of enhanced frictional contact zones associated with oceanic basement relief and weak material patches of underthrust sediment influences seismic coupling and possibly contributed to the heterogeneous slip distribution. Our seismic images resolve a steeply dipping splay fault, which originates at the décollement and terminates at the sea floor and which potentially contributes to tsunami generation during co-seismic activity.
Ionospheric Effects from the superbolid exploded over the Chelyabinsk area
NASA Astrophysics Data System (ADS)
Ruzhin, Yuri; Smirnov, Vladimir; Kuznetsov, Vladimir; Smirnova, Elena
The Chelyabinsk meteorite fall is undoubtedly the most documented in history. Its passage through the atmosphere was recorded by video and photographers, visual observers, infrasonic microphones, seismographs on the ground, and by satellites in orbit. The data of transionospheric sounding by signals from the GPS cluster satellites carried out in the zone of explosion of the Chelyabinsk meteoroid have been analyzed. The analysis has shown that the explosion had a very weak effect on the ionosphere. The observed ionospheric disturbances were asymmetric with respect to the explosion epicenter. The signals obtained were compared both in shape and in amplitude with the known surface explosions for which the diagnostics of the ionospheric effects had been made by radio techniques. Ionospheric effects in the form of acoustic-gravity waves (AGW) produced by 500-600 tons TNT explosions on the ground are detected with confidence both by vertical sounding and by GPS techniques. This allows us to suggest that the reported equivalent of the meteoroid explosion was obviously overestimated. The experiments on the injection of barium vapor (3.3 kg) carried out under similar conditions in the terminator zone revealed the response of the ionosphere in variations of the critical frequencies of the layer at a distance of 1500-2000 km (AGW with a period of 5-10 min). The absence of such ionospheric effects in the remote zone at 1500-1700 km from the epicenter of the bolide explosion in the case under discussion also makes us feel doubtful about the estimated explosion equivalent.
NASA Astrophysics Data System (ADS)
Yin, A.; Pappalardo, R. T.
2013-12-01
Detailed photogeologic mapping of the tiger-stripe fractures in the South Polar Terrain (SPT) of Enceladus indicates that these structures are left-slip faults and terminate at hook-shaped fold-thrust zones and/or Y-shaped horsetail splay-fault zones. The semi-square-shaped tectonic domain that hosts the tiger-stripe faults is bounded by right-slip and left-slip faults on the north and south edges and fold-thrust and extensional zones on the western and eastern edges. We explain the above observations by a passive bookshelf-faulting model in which individual tiger-stripe faults are bounded by deformable wall rocks accommodating distributed deformation. Based on topographic data, we suggest that gravitational spreading had caused the SPT to spread unevenly from west to east. This process was accommodated by right-slip and left-slip faulting on the north and south sides and thrusting and extension along the eastern and southern margins of the tiger-stripe tectonic domain. The uneven spreading, expressed by a gradual northward increase in the number of extensional faults and thrusts/folds along the western and eastern margins, was accommodated by distributed right-slip simple shear across the whole tiger-stripe tectonic domain. This mode of deformation in turn resulted in the development of a passive bookshelf-fault system characterized by left-slip faulting on individual tiger-stripe fractures.
Characterization and depositional and evolutionary history of the Apollo 17 deep drill core
NASA Technical Reports Server (NTRS)
Morris, R. V.; Lauer, H. V., Jr.; Gose, W. A.
1979-01-01
With a depth resolution of about 0.5 cm, the stratigraphy of the approximately 3 m Apollo 17 deep drill core by measurement of the total FeO concentration is characterized along with the FMR surface exposure (maturity) index Is/FeO, the metallic iron concentration Fe-vsm, and the FMR linewidth delta-H. For stratigraphic characterization, the first two parameters are the most important. Most of the core is characterized by a FeO concentration of approximately 15.5 wt. %; there is a more mafic zone in the upper approximately 75 cm where the maximum FeO concentration is approximately 18.5 wt. %, and a more felsic zone between approximately 225 and 260 cm where the minimum FeO concentration is approximately 14.0%. As indicated by Is/FeO, most of the soil in the core is submature to mature; the only immature zone is located between approximately 20 and 60 cm and is one of the most distinctive features in the core. A two stage model for the depositional and evolutionary history of the Apollo 17 deep drill core is proposed: (1) deposition by one event approximately 110 m.y. ago or deposition by a sequence of closely spaced events initating a maximum of approximately 200 m.y. ago and terminating approximately 110 m.y. ago, (2) in situ reworking (gardening) to a depth of approximately 26 cm in the period between approximately 110 m.y. ago and the present day.
Kelsey, Harvey M.; Ladinsky, Tyler C.; Staisch, Lydia; Sherrod, Brian; Blakely, Richard J.; Pratt, Thomas; Stephenson, William; Odum, Jackson K.; Wan, Elmira
2017-01-01
The Yakima folds of central Washington, USA, are prominent anticlines that are the primary tectonic features of the backarc of the northern Cascadia subduction zone. What accounts for their topographic expression and how much strain do they accommodate and over what time period? We investigate Manastash anticline, a north vergent fault propagation fold typical of structures in the fold province. From retrodeformation of line- and area-balanced cross sections, the crust has horizontally shortened by 11% (0.8–0.9 km). The fold, and by inference all other folds in the fold province, formed no earlier than 15.6 Ma as they developed on a landscape that was reset to negligible relief following voluminous outpouring of Grande Ronde Basalt. Deformation is accommodated on two fault sets including west-northwest striking frontal thrust faults and shorter north to northeast striking faults. The frontal thrust fault system is active with late Quaternary scarps at the base of the range front. The fault-cored Manastash anticline terminates to the east at the Naneum anticline and fault; activity on the north trending Naneum structures predates emplacement of the Grande Ronde Basalt. The west trending Yakima folds and west striking thrust faults, the shorter north to northeast striking faults, and the Naneum fault together constitute the tectonic structures that accommodate deformation in the low strain rate environment in the backarc of the Cascadia Subduction Zone.
Anatomy of the western Java plate interface from depth-migrated seismic images
Kopp, H.; Hindle, D.; Klaeschen, D.; Oncken, O.; Reichert, C.; Scholl, D.
2009-01-01
Newly pre-stack depth-migrated seismic images resolve the structural details of the western Java forearc and plate interface. The structural segmentation of the forearc into discrete mechanical domains correlates with distinct deformation styles. Approximately 2/3 of the trench sediment fill is detached and incorporated into frontal prism imbricates, while the floor sequence is underthrust beneath the d??collement. Western Java, however, differs markedly from margins such as Nankai or Barbados, where a uniform, continuous d??collement reflector has been imaged. In our study area, the plate interface reveals a spatially irregular, nonlinear pattern characterized by the morphological relief of subducted seamounts and thicker than average patches of underthrust sediment. The underthrust sediment is associated with a low velocity zone as determined from wide-angle data. Active underplating is not resolved, but likely contributes to the uplift of the large bivergent wedge that constitutes the forearc high. Our profile is located 100 km west of the 2006 Java tsunami earthquake. The heterogeneous d??collement zone regulates the friction behavior of the shallow subduction environment where the earthquake occurred. The alternating pattern of enhanced frictional contact zones associated with oceanic basement relief and weak material patches of underthrust sediment influences seismic coupling and possibly contributed to the heterogeneous slip distribution. Our seismic images resolve a steeply dipping splay fault, which originates at the d??collement and terminates at the sea floor and which potentially contributes to tsunami generation during co-seismic activity. ?? 2009 Elsevier B.V.
Tectonics of the ophiolite belt from Naga Hills and Andaman Islands, India
NASA Astrophysics Data System (ADS)
Acharyya, S. K.; Ray, K. K.; Sengupta, S.
1990-06-01
The ophiolitic rocks of Naga Hills-Andaman belt occur as rootless slices, gently dipping over the Paleogene flyschoid sediments, the presence of blue-schists in ophiolite melange indicates an involvement of the subduction process. Subduction was initiated prior to mid-Eocene as proved by the contemporaneous lower age limit of ophiolite-derived cover sediment as against the accreted ophiolites and olistostromal trench sediment. During the late Oligocene terminal collision between the Indian and Sino-Burmese blocks, basement slivers from the Sino-Burmese block, accreted ophiolites and trench sediments from the subduction zone were thrust westward as nappe and emplaced over the down-going Indian plate. The geometry of the ophiolites and the presence of a narrow negative gravity anomaly flanking their map extent, run counter to the conventional view that the Naga-Andaman belt marks the location of the suture. The root-zone of the ophiolite nappe representing the suture is marked by a partially-exposed eastern ophiolite belt of the same age and gravity-high zone, passing through central Burma-Sumatra-Java. The ophiolites of the Andaman and Naga Hills are also conventionally linked with the subduction activity, west of Andaman islands. This activity began only in late Miocene, much later than onland emplacement of the ophiolites; it further developed west of the suture in its southern part. Post-collisional northward movement of the Indian plate subparallel to the suture, also developed leaky dextral transcurrent faults close to the suture and caused Neogene-Quatemary volcanism in central Burma and elsewhere.
Transport of microplastics in coastal seas
NASA Astrophysics Data System (ADS)
Zhang, Hua
2017-12-01
Microplastic pollution of the marine environment has received increasing attention from scientists, the public, and policy makers over the last few years. Marine microplastics predominantly originate near the coast and can remain in the nearshore zone for some time. However, at present, there is little understanding of the fate and transport of microplastics in coastal regions. This paper provides a comprehensive overview of the physical processes involved in the movement of microplastics from estuaries to the continental shelf. The trajectory and speed of microplastics are controlled by their physical characteristics (density, size, and shape) and ocean dynamic conditions (wind, waves, tides, thermohaline gradients, and the influence of benthic sediments). Microplastic particles can be subjected to beaching, surface drifting, vertical mixing, and biofouling, as well as bed-load and suspended load transport processes, until reaching terminal deposition on beaches, in coastal marshes, in benthic sediments or until they are carried by ocean currents to subtropical convergence zones. The dynamic interaction of released microplastics with the shoreline is regulated by onshore/offshore transport, which is impacted by the source location as well as the geometry, vegetation, tidal regime, and wave direction. Wind and wave conditions dominate surface drifting of buoyant particles through Ekman drift, windage, and Stokes drift mechanisms. Neustic microplastic particles travel in the subsurface because of vertical mixing through wind-driven Langmuir circulation and heat cycling. Increasing accumulation of microplastics in benthic sediments needs to be quantitatively explored in terms of biofouling, deposition, entrainment, and transport dynamics. Further studies are required to understand the following: 1) the primary parameters (e.g., windage, terminal velocity, diffusivity, critical shear stress) that determine microplastic transport in different pathways; 2) dynamic distribution of microplastics in various coastal landscapes (e.g., wetlands, beaches, estuaries, lagoons, barrier islands, depocenters) regulated by hydrodynamic conditions; and 3) interactions between the physical transport processes and biochemical reactions (degradation, flocculation, biofouling, ingestions).
NASA Astrophysics Data System (ADS)
Funnell, M.; Peirce, C.; Robinson, A. H.; Watts, A. B.; Grevemeyer, I.
2016-12-01
Variations in tectonic forces and inputs to subduction systems generate, alter, and deform overriding crustal material. Although these processes are recorded in the crustal structure of volcanic arcs and their backarcs, the continuous nature of plate convergence superimposes subsequent episodes of crustal evolution on older features. Seismic imaging at modern subduction zones enhances our understanding of forearc development and variations in present-day deformation caused by inherited structures. In 2011 a set of multichannel and wide-angle seismic profiles imaged the forearc-arc crust and upper mantle structure along the 2700 km-long NNE-SSW trending Tonga-Kermadec subduction zone. The Tonga forearc region exhibits an 100 km-wide, 2 km high bathymetric elevation, with a 3 km-thick upper and mid-crust (Vp <6 km s-1), and a lower-crustal ridge 30 km wide comprising velocities up to 7.4 km s-1 that characterize an extinct Eocene ( 50 Ma) arc. By contrast, the active arc is <10 km wide and exhibits lower-crustal velocities below 7.0 km s-1, most likely representing intermediate compositions. This structural change suggests significant evolution, alteration, and modification of the overriding crust since the onset of subduction at this margin. Gravity anomaly modelling suggests that the extinct arc within the Tonga forearc region comprises relatively dense mafic-ultrabasic material that extends south beneath the Kermadec forearc and terminates at 32°S. The apparent southern termination of the extinct arc coincides with the partitioning of morphological features at 32°S, including a 10-km westward-step of the active arc and a 1.5 km deeper backarc to the south. We propose that tectonic partitioning about the 32°S boundary is the result of variations in the inherited crustal structure, which is divided by the presence and absence, to the north and south respectively, of the extinct volcanic arc.
NASA Astrophysics Data System (ADS)
Guglielmi, Y.; Nussbaum, C.; Birkholzer, J. T.; De Barros, L.; Cappa, F.
2017-12-01
There is a large spectrum of fault slow rupture processes such as stable creep and slow slip that radiate no or little seismic energy, and which relationships to normal earthquakes and fault permeability variations are enigmatic. Here we present measurements of a fault slow rupture, permeability variation and seismicity induced by fluid-injection in a fault affecting the Opalinus clay (Mt Terri URL, Switzerland) at a depth of 300 m. We observe multiple dilatant slow slip events ( 0.1-to-30 microm/s) associated with factor-of-1000 increase of permeability, and terminated by a magnitude -2.5 main seismic event associated with a swarm of very small magnitude ones. Using fully coupled numerical modeling, we calculate that the short term velocity strengthening behavior observed experimentally at laboratory scale is overcome by longer slip weakening that may be favored by slip induced dilation. Two monitoring points set across the fault allow estimating that, at the onset of the seismicity, the radius of the fault patch invaded by pressurized fluid is 9-to-11m which is in good accordance with a fault instability triggering when the dimensions of the critical slip distance are overcome. We then observe that the long term slip weakening is associated to an exponential permeability increase caused by a cumulated effective normal stress drop of about 3.4MPa which controls the successive slip activation of multiple fracture planes inducing a 0.1MPa shear stress drop in the fault zone. Therefore, our data suggest that the induced earthquake that terminated the rupture sequence may have represented enough dynamic stress release to arrest the fault permeability increase, suggesting the high sensitivity of the slow rupture processes to the structural heterogeneity of the fault zone hydromechanical properties.
NASA Astrophysics Data System (ADS)
Fabre, M.; Patriat, M.; Collot, J.; Danyushevsky, L. V.; Meffre, S.; Falloon, T.; Rouillard, P.; Pelletier, B.; Roach, M. J.; Fournier, M.
2015-12-01
Geophysical data acquired during three expeditions of the R/V Southern Surveyor allows us to characterize the deformation of the upper plate at the southern termination of the New Hebrides subduction zone where it bends 90° eastward along the Hunter Ridge. As shown by GPS measurements and earthquake slip vectors systematically orthogonal to the trench, this 90° bend does not mark a transition from subduction to strike slip as usually observed at subduction termination. Here the convergence direction remains continuously orthogonal to the trench notwithstanding its bend. Multibeam bathymetric data acquired in the North Fiji Basin reveals active deformation and fragmentation of the upper plate. It shows the southward propagation of a N-S back-arc spreading ridge into the pre-existing volcanic arc, and the connection of the southern end of the spreading axis with an oblique active rift in the active arc. Ultimately the active arc lithosphere is sheared as spreading progressively supersedes rifting. Consequently to such incursion of back-arc basin extension into the arc, peeled off and drifted pieces of arc crust are progressively isolated into the back-arc basin. Another consequence is that the New Hebrides arc is split in two distinct microplates, which move independently relative to the lower plate, and thereby define two different subduction systems. We suggest arc fragmentation could be a consequence of the incipient collision of the Loyalty Ridge with the New Hebrides Arc. We further speculate that this kinematic change could have resulted, less than two million year ago, in the initiation of a new subduction orthogonal to the New Hebrides Subduction possibly along the paleo STEP fault. In this geodynamic setting, with an oceanic lithosphere subducting beneath a sheared volcanic arc, a particularly wide range of primitive subduction-related magmas have been produced including adakites, island arc tholeiites, back-arc basin basalts, and medium-K subduction-related lavas.
Sinkko, Hanna; Lukkari, Kaarina; Sihvonen, Leila M.; Sivonen, Kaarina; Leivuori, Mirja; Rantanen, Matias; Paulin, Lars; Lyra, Christina
2013-01-01
In the sedimental organic matter of eutrophic continental seas, such as the largest dead zone in the world, the Baltic Sea, bacteria may directly participate in nutrient release by mineralizing organic matter or indirectly by altering the sediment’s ability to retain nutrients. Here, we present a case study of a hypoxic sea, which receives riverine nutrient loading and in which microbe-mediated vicious cycles of nutrients prevail. We showed that bacterial communities changed along the horizontal loading and vertical mineralization gradients in the Gulf of Finland of the Baltic Sea, using multivariate statistics of terminal restriction fragments and sediment chemical, spatial and other properties of the sampling sites. The change was mainly explained by concentrations of organic carbon, nitrogen and phosphorus, which showed strong positive correlation with Flavobacteria, Sphingobacteria, Alphaproteobacteria and Gammaproteobacteria. These bacteria predominated in the most organic-rich coastal surface sediments overlain by oxic bottom water, whereas sulphate-reducing bacteria, particularly the genus Desulfobacula, prevailed in the reduced organic-rich surface sediments in the open sea. They correlated positively with organic nitrogen and phosphorus, as well as manganese oxides. These relationships suggest that the bacterial groups participated in the aerobic and anaerobic degradation of organic matter and contributed to nutrient cycling. The high abundance of sulphate reducers in the surficial sediment layers reflects the persistence of eutrophication-induced hypoxia causing ecosystem-level changes in the Baltic Sea. The sulphate reducers began to decrease below depths of 20 cm, where members of the family Anaerolineaceae (phylum Chloroflexi) increased, possibly taking part in terminal mineralization processes. Our study provides valuable information on how organic loading affects sediment bacterial community compositions, which consequently may maintain active nutrient recycling. This information is needed to improve our understanding on nutrient cycling in shallow seas where the dead zones are continuously spreading worldwide. PMID:23825619
NASA Astrophysics Data System (ADS)
Bradwell, Tom; Small, David; Fabel, Derek; Dove, Dayton; Cofaigh, Colm O.; Clark, Chris; Consortium, Britice-Chrono
2016-04-01
Chronologically constrained studies of former ice-sheet extents and dynamics are important for understanding past cryospheric responses and modelling future ice-sheet and sea-level change. As part of the BRITICE-CHRONO project, we present new geomorphological and chronological data from a marine-terminating ice stream system in NW Europe that operated during the Late Weichselian Glaciation. A suite of 51 cosmogenic-nuclide exposure ages from ice sheet moraines and glacially transported boulders constrain the maximum extent of the ice sheet on the continental shelf (~28 ka BP) and its subsequent retreat, between ~27 and 16 ka BP, into a large marine embayment (ca. 7000 km2; the Minch, NW Scotland). Recently acquired swath bathymetry and acoustic sub-bottom profiler data reveal several large transverse grounding-zone wedges up to 40 m thick and 5 km wide with diagnostic acoustic-facies architecture. These seabed sediment wedges mark former quasi-stable positions of grounded marine-terminating ice-stream fronts; their size and thickness suggest long-lived stillstands of the order of centuries. Statistically significant clusters of exposure ages from glacial deposits on islands and intervening headlands shed important new light on the age of these marine grounding-zone wedges and, by inference, the rate and timing of Minch palaeo-ice stream retreat. We find strong evidence for episodic ice stream retreat on the continental shelf between ~28-24 ka BP, in the outer Minch between ~24-22 ka BP, and in the central Minch between 22-18.5 ka BP. In contrast, final ice stream deglaciation (<18 ka) across the deepest parts of the inner Minch embayment, was probably rapid and uninterrupted - with the ice sheet margin at or close to the present-day coastline in NW Scotland by 16.1 ka BP. It is hoped that these results will form the empirical basis for future ice-sheet modelling of this dynamically sensitive sector of the British-Irish Ice Sheet.
Beacon Hill end moraine, Boston: new explanation of an important urban feature
Kaye, Clifford A.; Coates, Donald R.
1976-01-01
The usefulness of geology to engineers is in direct proportion to how well it helps us predict the subsurface; these predictions, in turn, depend on our knowledge of the geomorphic processes that molded the terrain. The uncertainties of interpretation are particularly great in glaciated terrain because our understanding of both glacial processes and history is so incomplete, a fact well illustrated in Beacon Hill. Recent construction activities in the eastern part of the hill, until now classified as a drumlin, have shown that it is better interpreted as an end moraine formed by a Wisconsonian glacial readvance. Instead of the firm till that was anticipated as foundation material, excavations exposed a complex of sand, gravel, and clay, with only minor zones of till. The structure of these deposits strongly suggests that originally they were plates of the glacial bed that froze to the glacier and were transported englacially. Thrust faulting and other deformations are glacial structures formed within the ice in the glacier's terminal zone. In spite of the complex englacial history, these deposits lost little of their original appearance and intergranular relationships. Upon deglaciation, the frozen moraine thawed, and slumping formed complex secondary structures on the ridge's lower flanks.
NASA Astrophysics Data System (ADS)
Ovsepyan, E.; Ivanova, E. V.; Tiedemann, R.
2017-12-01
Seasonally sea-ice covered Bering Sea is known to be a sensitive region to study rapid climatic oscillations. Based on benthic (BF) and planktic (PF) foraminiferal data from two sediment cores SO201-2-85KL (85KL, w.d. 968 m) and SO201-2-77KL (77KL, w.d. 2163 m) we reconstruct variations in intensity of oxygen minimum zone (OMZ) and its relation to sea-surface bioproductivity in the central and southern parts of the Shirshov Ridge, western Bering Sea, during the Termination I. A prevalence of suboxic BF group (Kaiho, 1994) in both cores mirrors moderately oxygenated intermediate and deep waters during LGM-Heinrich I interval. Rapid increase in percentages of dysoxic group is registered in the core 77KL at the onset of Bølling/Allerød. This implies that relatively low-oxygen conditions developed at 2 km water depths in the southwestern Bering Sea, but occurrence (20-30%) of suboxic group suggests that oxygen depletion was not dramatic. Simultaneous spikes of high-productivity species point to a bioproductivity rise above the southern part of the ridge. Increase in bioproductivity and decrease in oxygen content are detected 0.9 kyr later above the central part of Shirshov Ridge than above the southern one. This delay might reflect a gradual sea ice retreat from station 77 KL to 85KL during the global warming and sea level rise. Moderate bottom-water oxygenation is suggested for the intermediate depths of 1 km whereas no changes in relative oxygen content are found at 2 km below sea level during the Younger Dryas. Concurrent decrease in bioproductivity is reconstructed from BF records from the core 85KL. However, presence of high-productivity species and elevated BF accumulation rates in the core 77KL point to higher organic matter flux to the sea floor in the southern part of the ridge at the end of Younger Dryas. For the Early Holocene, bioproductivity rise and oxygen depletion in the intermediate waters are inferred from BF data. Strong dominance of dysoxic group in the 85KL indicates that oxygen content at the intermediate depths was much lower during the Early Holocene than during the Bølling/Allerød. The results provide evidence for complex development of OMZ in the western Bering Sea during the Termination I. They also demonstrate high potential to extend such studies to the North Pacific realm.