Sample records for perl programming language

  1. A Tutorial in Creating Web-Enabled Databases with Inmagic DB/TextWorks through ODBC.

    ERIC Educational Resources Information Center

    Breeding, Marshall

    2000-01-01

    Explains how to create Web-enabled databases. Highlights include Inmagic's DB/Text WebPublisher product called DB/TextWorks; ODBC (Open Database Connectivity) drivers; Perl programming language; HTML coding; Structured Query Language (SQL); Common Gateway Interface (CGI) programming; and examples of HTML pages and Perl scripts. (LRW)

  2. A comparison of common programming languages used in bioinformatics.

    PubMed

    Fourment, Mathieu; Gillings, Michael R

    2008-02-05

    The performance of different programming languages has previously been benchmarked using abstract mathematical algorithms, but not using standard bioinformatics algorithms. We compared the memory usage and speed of execution for three standard bioinformatics methods, implemented in programs using one of six different programming languages. Programs for the Sellers algorithm, the Neighbor-Joining tree construction algorithm and an algorithm for parsing BLAST file outputs were implemented in C, C++, C#, Java, Perl and Python. Implementations in C and C++ were fastest and used the least memory. Programs in these languages generally contained more lines of code. Java and C# appeared to be a compromise between the flexibility of Perl and Python and the fast performance of C and C++. The relative performance of the tested languages did not change from Windows to Linux and no clear evidence of a faster operating system was found. Source code and additional information are available from http://www.bioinformatics.org/benchmark/. This benchmark provides a comparison of six commonly used programming languages under two different operating systems. The overall comparison shows that a developer should choose an appropriate language carefully, taking into account the performance expected and the library availability for each language.

  3. A comparison of common programming languages used in bioinformatics

    PubMed Central

    Fourment, Mathieu; Gillings, Michael R

    2008-01-01

    Background The performance of different programming languages has previously been benchmarked using abstract mathematical algorithms, but not using standard bioinformatics algorithms. We compared the memory usage and speed of execution for three standard bioinformatics methods, implemented in programs using one of six different programming languages. Programs for the Sellers algorithm, the Neighbor-Joining tree construction algorithm and an algorithm for parsing BLAST file outputs were implemented in C, C++, C#, Java, Perl and Python. Results Implementations in C and C++ were fastest and used the least memory. Programs in these languages generally contained more lines of code. Java and C# appeared to be a compromise between the flexibility of Perl and Python and the fast performance of C and C++. The relative performance of the tested languages did not change from Windows to Linux and no clear evidence of a faster operating system was found. Source code and additional information are available from Conclusion This benchmark provides a comparison of six commonly used programming languages under two different operating systems. The overall comparison shows that a developer should choose an appropriate language carefully, taking into account the performance expected and the library availability for each language. PMID:18251993

  4. Perl-speaks-NONMEM (PsN)--a Perl module for NONMEM related programming.

    PubMed

    Lindbom, Lars; Ribbing, Jakob; Jonsson, E Niclas

    2004-08-01

    The NONMEM program is the most widely used nonlinear regression software in population pharmacokinetic/pharmacodynamic (PK/PD) analyses. In this article we describe a programming library, Perl-speaks-NONMEM (PsN), intended for programmers that aim at using the computational capability of NONMEM in external applications. The library is object oriented and written in the programming language Perl. The classes of the library are built around NONMEM's data, model and output files. The specification of the NONMEM model is easily set or changed through the model and data file classes while the output from a model fit is accessed through the output file class. The classes have methods that help the programmer perform common repetitive tasks, e.g. summarising the output from a NONMEM run, setting the initial estimates of a model based on a previous run or truncating values over a certain threshold in the data file. PsN creates a basis for the development of high-level software using NONMEM as the regression tool.

  5. Sharing programming resources between Bio* projects through remote procedure call and native call stack strategies.

    PubMed

    Prins, Pjotr; Goto, Naohisa; Yates, Andrew; Gautier, Laurent; Willis, Scooter; Fields, Christopher; Katayama, Toshiaki

    2012-01-01

    Open-source software (OSS) encourages computer programmers to reuse software components written by others. In evolutionary bioinformatics, OSS comes in a broad range of programming languages, including C/C++, Perl, Python, Ruby, Java, and R. To avoid writing the same functionality multiple times for different languages, it is possible to share components by bridging computer languages and Bio* projects, such as BioPerl, Biopython, BioRuby, BioJava, and R/Bioconductor. In this chapter, we compare the two principal approaches for sharing software between different programming languages: either by remote procedure call (RPC) or by sharing a local call stack. RPC provides a language-independent protocol over a network interface; examples are RSOAP and Rserve. The local call stack provides a between-language mapping not over the network interface, but directly in computer memory; examples are R bindings, RPy, and languages sharing the Java Virtual Machine stack. This functionality provides strategies for sharing of software between Bio* projects, which can be exploited more often. Here, we present cross-language examples for sequence translation, and measure throughput of the different options. We compare calling into R through native R, RSOAP, Rserve, and RPy interfaces, with the performance of native BioPerl, Biopython, BioJava, and BioRuby implementations, and with call stack bindings to BioJava and the European Molecular Biology Open Software Suite. In general, call stack approaches outperform native Bio* implementations and these, in turn, outperform RPC-based approaches. To test and compare strategies, we provide a downloadable BioNode image with all examples, tools, and libraries included. The BioNode image can be run on VirtualBox-supported operating systems, including Windows, OSX, and Linux.

  6. TkPl_SU: An Open-source Perl Script Builder for Seismic Unix

    NASA Astrophysics Data System (ADS)

    Lorenzo, J. M.

    2017-12-01

    TkPl_SU (beta) is a graphical user interface (GUI) to select parameters for Seismic Unix (SU) modules. Seismic Unix (Stockwell, 1999) is a widely distributed free software package for processing seismic reflection and signal processing. Perl/Tk is a mature, well-documented and free object-oriented graphical user interface for Perl. In a classroom environment, shell scripting of SU modules engages students and helps focus on the theoretical limitations and strengths of signal processing. However, complex interactive processing stages, e.g., selection of optimal stacking velocities, killing bad data traces, or spectral analysis requires advanced flows beyond the scope of introductory classes. In a research setting, special functionality from other free seismic processing software such as SioSeis (UCSD-NSF) can be incorporated readily via an object-oriented style to programming. An object oriented approach is a first step toward efficient extensible programming of multi-step processes, and a simple GUI simplifies parameter selection and decision making. Currently, in TkPl_SU, Perl 5 packages wrap 19 of the most common SU modules that are used in teaching undergraduate and first-year graduate student classes (e.g., filtering, display, velocity analysis and stacking). Perl packages (classes) can advantageously add new functionality around each module and clarify parameter names for easier usage. For example, through the use of methods, packages can isolate the user from repetitive control structures, as well as replace the names of abbreviated parameters with self-describing names. Moose, an extension of the Perl 5 object system, greatly facilitates an object-oriented style. Perl wrappers are self-documenting via Perl programming document markup language.

  7. Development and Evaluation of a Thai Learning System on the Web Using Natural Language Processing.

    ERIC Educational Resources Information Center

    Dansuwan, Suyada; Nishina, Kikuko; Akahori, Kanji; Shimizu, Yasutaka

    2001-01-01

    Describes the Thai Learning System, which is designed to help learners acquire the Thai word order system. The system facilitates the lessons on the Web using HyperText Markup Language and Perl programming, which interfaces with natural language processing by means of Prolog. (Author/VWL)

  8. The Geoinformatica free and open source software stack

    NASA Astrophysics Data System (ADS)

    Jolma, A.

    2012-04-01

    The Geoinformatica free and open source software (FOSS) stack is based mainly on three established FOSS components, namely GDAL, GTK+, and Perl. GDAL provides access to a very large selection of geospatial data formats and data sources, a generic geospatial data model, and a large collection of geospatial analytical and processing functionality. GTK+ and the Cairo graphics library provide generic graphics and graphical user interface capabilities. Perl is a programming language, for which there is a very large set of FOSS modules for a wide range of purposes and which can be used as an integrative tool for building applications. In the Geoinformatica stack, data storages such as FOSS RDBMS PostgreSQL with its geospatial extension PostGIS can be used below the three above mentioned components. The top layer of Geoinformatica consists of a C library and several Perl modules. The C library comprises a general purpose raster algebra library, hydrological terrain analysis functions, and visualization code. The Perl modules define a generic visualized geospatial data layer and subclasses for raster and vector data and graphs. The hydrological terrain functions are already rather old and they suffer for example from the requirement of in-memory rasters. Newer research conducted using the platform include basic geospatial simulation modeling, visualization of ecological data, linking with a Bayesian network engine for spatial risk assessment in coastal areas, and developing standards-based distributed water resources information systems in Internet. The Geoinformatica stack constitutes a platform for geospatial research, which is targeted towards custom analytical tools, prototyping and linking with external libraries. Writing custom analytical tools is supported by the Perl language and the large collection of tools that are available especially in GDAL and Perl modules. Prototyping is supported by the GTK+ library, the GUI tools, and the support for object-oriented programming in Perl. New feature types, geospatial layer classes, and tools as extensions with specific features can be defined, used, and studied. Linking with external libraries is possible using the Perl foreign function interface tools or with generic tools such as Swig. We are interested in implementing and testing linking Geoinformatica with existing or new more specific hydrological FOSS.

  9. Introduction to Python for CMF Authority Users

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pritchett-Sheats, Lori A.

    This talk is a very broad over view of Python that highlights key features in the language used in the Common Model Framework (CMF). I assume that the audience has some programming experience in a shell scripting language (C shell, Bash, PERL) or other high level language (C/C++/ Fortran). The talk will cover Python data types, classes (objects) and basic programming constructs. The talk concludes with slides describing how I developed the basic classes for a TITANS homework assignment.

  10. Pressure Ratio to Thermal Environments

    NASA Technical Reports Server (NTRS)

    Lopez, Pedro; Wang, Winston

    2012-01-01

    A pressure ratio to thermal environments (PRatTlE.pl) program is a Perl language code that estimates heating at requested body point locations by scaling the heating at a reference location times a pressure ratio factor. The pressure ratio factor is the ratio of the local pressure at the reference point and the requested point from CFD (computational fluid dynamics) solutions. This innovation provides pressure ratio-based thermal environments in an automated and traceable method. Previously, the pressure ratio methodology was implemented via a Microsoft Excel spreadsheet and macro scripts. PRatTlE is able to calculate heating environments for 150 body points in less than two minutes. PRatTlE is coded in Perl programming language, is command-line-driven, and has been successfully executed on both the HP and Linux platforms. It supports multiple concurrent runs. PRatTlE contains error trapping and input file format verification, which allows clear visibility into the input data structure and intermediate calculations.

  11. autokonf - A Configuration Script Generator Implemented in Perl

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Reus, J F

    This paper discusses configuration scripts in general and the scripting language issues involved. A brief description of GNU autoconf is provided along with a contrasting overview of autokonf, a configuration script generator implemented in Perl, whose macros are implemented in Perl, generating a configuration script in Perl. It is very portable, easily extensible, and readily mastered.

  12. ATHENA, ARTEMIS, HEPHAESTUS: data analysis for X-ray absorption spectropscopy using IFEFFIT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ravel, B.; Newville, M.; UC)

    2010-07-20

    A software package for the analysis of X-ray absorption spectroscopy (XAS) data is presented. This package is based on the IFEFFIT library of numerical and XAS algorithms and is written in the Perl programming language using the Perl/Tk graphics toolkit. The programs described here are: (i) ATHENA, a program for XAS data processing, (ii) ARTEMIS, a program for EXAFS data analysis using theoretical standards from FEFF and (iii) HEPHAESTUS, a collection of beamline utilities based on tables of atomic absorption data. These programs enable high-quality data analysis that is accessible to novices while still powerful enough to meet the demandsmore » of an expert practitioner. The programs run on all major computer platforms and are freely available under the terms of a free software license.« less

  13. The WORM site: worm.csirc.net

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jones, T.

    2000-07-01

    The Write One, Run Many (WORM) site (worm.csirc.net) is the on-line home of the WORM language and is hosted by the Criticality Safety Information Resource Center (CSIRC) (www.csirc.net). The purpose of this web site is to create an on-line community for WORM users to gather, share, and archive WORM-related information. WORM is an embedded, functional, programming language designed to facilitate the creation of input decks for computer codes that take standard ASCII text files as input. A functional programming language is one that emphasizes the evaluation of expressions, rather than execution of commands. The simplest and perhaps most common examplemore » of a functional language is a spreadsheet such as Microsoft Excel. The spreadsheet user specifies expressions to be evaluated, while the spreadsheet itself determines the commands to execute, as well as the order of execution/evaluation. WORM functions in a similar fashion and, as a result, is very simple to use and easy to learn. WORM improves the efficiency of today's criticality safety analyst by allowing: (1) input decks for parameter studies to be created quickly and easily; (2) calculations and variables to be embedded into any input deck, thus allowing for meaningful parameter specifications; (3) problems to be specified using any combination of units; and (4) complex mathematically defined models to be created. WORM is completely written in Perl. Running on all variants of UNIX, Windows, MS-DOS, MacOS, and many other operating systems, Perl is one of the most portable programming languages available. As such, WORM works on practically any computer platform.« less

  14. Informatics technology mimics ecology: dense, mutualistic collaboration networks are associated with higher publication rates.

    PubMed

    Sorani, Marco D

    2012-01-01

    Information technology (IT) adoption enables biomedical research. Publications are an accepted measure of research output, and network models can describe the collaborative nature of publication. In particular, ecological networks can serve as analogies for publication and technology adoption. We constructed network models of adoption of bioinformatics programming languages and health IT (HIT) from the literature.We selected seven programming languages and four types of HIT. We performed PubMed searches to identify publications since 2001. We calculated summary statistics and analyzed spatiotemporal relationships. Then, we assessed ecological models of specialization, cooperativity, competition, evolution, biodiversity, and stability associated with publications.Adoption of HIT has been variable, while scripting languages have experienced rapid adoption. Hospital systems had the largest HIT research corpus, while Perl had the largest language corpus. Scripting languages represented the largest connected network components. The relationship between edges and nodes was linear, though Bioconductor had more edges than expected and Perl had fewer. Spatiotemporal relationships were weak. Most languages shared a bioinformatics specialization and appeared mutualistic or competitive. HIT specializations varied. Specialization was highest for Bioconductor and radiology systems. Specialization and cooperativity were positively correlated among languages but negatively correlated among HIT. Rates of language evolution were similar. Biodiversity among languages grew in the first half of the decade and stabilized, while diversity among HIT was variable but flat. Compared with publications in 2001, correlation with publications one year later was positive while correlation after ten years was weak and negative.Adoption of new technologies can be unpredictable. Spatiotemporal relationships facilitate adoption but are not sufficient. As with ecosystems, dense, mutualistic, specialized co-habitation is associated with faster growth. There are rapidly changing trends in external technological and macroeconomic influences. We propose that a better understanding of how technologies are adopted can facilitate their development.

  15. The Bioperl Toolkit: Perl Modules for the Life Sciences

    PubMed Central

    Stajich, Jason E.; Block, David; Boulez, Kris; Brenner, Steven E.; Chervitz, Stephen A.; Dagdigian, Chris; Fuellen, Georg; Gilbert, James G.R.; Korf, Ian; Lapp, Hilmar; Lehväslaiho, Heikki; Matsalla, Chad; Mungall, Chris J.; Osborne, Brian I.; Pocock, Matthew R.; Schattner, Peter; Senger, Martin; Stein, Lincoln D.; Stupka, Elia; Wilkinson, Mark D.; Birney, Ewan

    2002-01-01

    The Bioperl project is an international open-source collaboration of biologists, bioinformaticians, and computer scientists that has evolved over the past 7 yr into the most comprehensive library of Perl modules available for managing and manipulating life-science information. Bioperl provides an easy-to-use, stable, and consistent programming interface for bioinformatics application programmers. The Bioperl modules have been successfully and repeatedly used to reduce otherwise complex tasks to only a few lines of code. The Bioperl object model has been proven to be flexible enough to support enterprise-level applications such as EnsEMBL, while maintaining an easy learning curve for novice Perl programmers. Bioperl is capable of executing analyses and processing results from programs such as BLAST, ClustalW, or the EMBOSS suite. Interoperation with modules written in Python and Java is supported through the evolving BioCORBA bridge. Bioperl provides access to data stores such as GenBank and SwissProt via a flexible series of sequence input/output modules, and to the emerging common sequence data storage format of the Open Bioinformatics Database Access project. This study describes the overall architecture of the toolkit, the problem domains that it addresses, and gives specific examples of how the toolkit can be used to solve common life-sciences problems. We conclude with a discussion of how the open-source nature of the project has contributed to the development effort. [Supplemental material is available online at www.genome.org. Bioperl is available as open-source software free of charge and is licensed under the Perl Artistic License (http://www.perl.com/pub/a/language/misc/Artistic.html). It is available for download at http://www.bioperl.org. Support inquiries should be addressed to bioperl-l@bioperl.org.] PMID:12368254

  16. Open source clustering software.

    PubMed

    de Hoon, M J L; Imoto, S; Nolan, J; Miyano, S

    2004-06-12

    We have implemented k-means clustering, hierarchical clustering and self-organizing maps in a single multipurpose open-source library of C routines, callable from other C and C++ programs. Using this library, we have created an improved version of Michael Eisen's well-known Cluster program for Windows, Mac OS X and Linux/Unix. In addition, we generated a Python and a Perl interface to the C Clustering Library, thereby combining the flexibility of a scripting language with the speed of C. The C Clustering Library and the corresponding Python C extension module Pycluster were released under the Python License, while the Perl module Algorithm::Cluster was released under the Artistic License. The GUI code Cluster 3.0 for Windows, Macintosh and Linux/Unix, as well as the corresponding command-line program, were released under the same license as the original Cluster code. The complete source code is available at http://bonsai.ims.u-tokyo.ac.jp/mdehoon/software/cluster. Alternatively, Algorithm::Cluster can be downloaded from CPAN, while Pycluster is also available as part of the Biopython distribution.

  17. BioC implementations in Go, Perl, Python and Ruby

    PubMed Central

    Liu, Wanli; Islamaj Doğan, Rezarta; Kwon, Dongseop; Marques, Hernani; Rinaldi, Fabio; Wilbur, W. John; Comeau, Donald C.

    2014-01-01

    As part of a communitywide effort for evaluating text mining and information extraction systems applied to the biomedical domain, BioC is focused on the goal of interoperability, currently a major barrier to wide-scale adoption of text mining tools. BioC is a simple XML format, specified by DTD, for exchanging data for biomedical natural language processing. With initial implementations in C++ and Java, BioC provides libraries of code for reading and writing BioC text documents and annotations. We extend BioC to Perl, Python, Go and Ruby. We used SWIG to extend the C++ implementation for Perl and one Python implementation. A second Python implementation and the Ruby implementation use native data structures and libraries. BioC is also implemented in the Google language Go. BioC modules are functional in all of these languages, which can facilitate text mining tasks. BioC implementations are freely available through the BioC site: http://bioc.sourceforge.net. Database URL: http://bioc.sourceforge.net/ PMID:24961236

  18. Informatics Technology Mimics Ecology: Dense, Mutualistic Collaboration Networks Are Associated with Higher Publication Rates

    PubMed Central

    Sorani, Marco D.

    2012-01-01

    Information technology (IT) adoption enables biomedical research. Publications are an accepted measure of research output, and network models can describe the collaborative nature of publication. In particular, ecological networks can serve as analogies for publication and technology adoption. We constructed network models of adoption of bioinformatics programming languages and health IT (HIT) from the literature. We selected seven programming languages and four types of HIT. We performed PubMed searches to identify publications since 2001. We calculated summary statistics and analyzed spatiotemporal relationships. Then, we assessed ecological models of specialization, cooperativity, competition, evolution, biodiversity, and stability associated with publications. Adoption of HIT has been variable, while scripting languages have experienced rapid adoption. Hospital systems had the largest HIT research corpus, while Perl had the largest language corpus. Scripting languages represented the largest connected network components. The relationship between edges and nodes was linear, though Bioconductor had more edges than expected and Perl had fewer. Spatiotemporal relationships were weak. Most languages shared a bioinformatics specialization and appeared mutualistic or competitive. HIT specializations varied. Specialization was highest for Bioconductor and radiology systems. Specialization and cooperativity were positively correlated among languages but negatively correlated among HIT. Rates of language evolution were similar. Biodiversity among languages grew in the first half of the decade and stabilized, while diversity among HIT was variable but flat. Compared with publications in 2001, correlation with publications one year later was positive while correlation after ten years was weak and negative. Adoption of new technologies can be unpredictable. Spatiotemporal relationships facilitate adoption but are not sufficient. As with ecosystems, dense, mutualistic, specialized co-habitation is associated with faster growth. There are rapidly changing trends in external technological and macroeconomic influences. We propose that a better understanding of how technologies are adopted can facilitate their development. PMID:22279593

  19. COD::CIF::Parser: an error-correcting CIF parser for the Perl language.

    PubMed

    Merkys, Andrius; Vaitkus, Antanas; Butkus, Justas; Okulič-Kazarinas, Mykolas; Kairys, Visvaldas; Gražulis, Saulius

    2016-02-01

    A syntax-correcting CIF parser, COD::CIF::Parser , is presented that can parse CIF 1.1 files and accurately report the position and the nature of the discovered syntactic problems. In addition, the parser is able to automatically fix the most common and the most obvious syntactic deficiencies of the input files. Bindings for Perl, C and Python programming environments are available. Based on COD::CIF::Parser , the cod-tools package for manipulating the CIFs in the Crystallography Open Database (COD) has been developed. The cod-tools package has been successfully used for continuous updates of the data in the automated COD data deposition pipeline, and to check the validity of COD data against the IUCr data validation guidelines. The performance, capabilities and applications of different parsers are compared.

  20. A resource for benchmarking the usefulness of protein structure models.

    PubMed

    Carbajo, Daniel; Tramontano, Anna

    2012-08-02

    Increasingly, biologists and biochemists use computational tools to design experiments to probe the function of proteins and/or to engineer them for a variety of different purposes. The most effective strategies rely on the knowledge of the three-dimensional structure of the protein of interest. However it is often the case that an experimental structure is not available and that models of different quality are used instead. On the other hand, the relationship between the quality of a model and its appropriate use is not easy to derive in general, and so far it has been analyzed in detail only for specific application. This paper describes a database and related software tools that allow testing of a given structure based method on models of a protein representing different levels of accuracy. The comparison of the results of a computational experiment on the experimental structure and on a set of its decoy models will allow developers and users to assess which is the specific threshold of accuracy required to perform the task effectively. The ModelDB server automatically builds decoy models of different accuracy for a given protein of known structure and provides a set of useful tools for their analysis. Pre-computed data for a non-redundant set of deposited protein structures are available for analysis and download in the ModelDB database. IMPLEMENTATION, AVAILABILITY AND REQUIREMENTS: Project name: A resource for benchmarking the usefulness of protein structure models. Project home page: http://bl210.caspur.it/MODEL-DB/MODEL-DB_web/MODindex.php.Operating system(s): Platform independent. Programming language: Perl-BioPerl (program); mySQL, Perl DBI and DBD modules (database); php, JavaScript, Jmol scripting (web server). Other requirements: Java Runtime Environment v1.4 or later, Perl, BioPerl, CPAN modules, HHsearch, Modeller, LGA, NCBI Blast package, DSSP, Speedfill (Surfnet) and PSAIA. License: Free. Any restrictions to use by non-academics: No.

  1. BioC implementations in Go, Perl, Python and Ruby.

    PubMed

    Liu, Wanli; Islamaj Doğan, Rezarta; Kwon, Dongseop; Marques, Hernani; Rinaldi, Fabio; Wilbur, W John; Comeau, Donald C

    2014-01-01

    As part of a communitywide effort for evaluating text mining and information extraction systems applied to the biomedical domain, BioC is focused on the goal of interoperability, currently a major barrier to wide-scale adoption of text mining tools. BioC is a simple XML format, specified by DTD, for exchanging data for biomedical natural language processing. With initial implementations in C++ and Java, BioC provides libraries of code for reading and writing BioC text documents and annotations. We extend BioC to Perl, Python, Go and Ruby. We used SWIG to extend the C++ implementation for Perl and one Python implementation. A second Python implementation and the Ruby implementation use native data structures and libraries. BioC is also implemented in the Google language Go. BioC modules are functional in all of these languages, which can facilitate text mining tasks. BioC implementations are freely available through the BioC site: http://bioc.sourceforge.net. Database URL: http://bioc.sourceforge.net/ Published by Oxford University Press 2014. This work is written by US Government employees and is in the public domain in the US.

  2. SCTE: An open-source Perl framework for testing equipment control and data acquisition

    NASA Astrophysics Data System (ADS)

    Mostaço-Guidolin, Luiz C.; Frigori, Rafael B.; Ruchko, Leonid; Galvão, Ricardo M. O.

    2012-07-01

    SCTE intends to provide a simple, yet powerful, framework for building data acquisition and equipment control systems for experimental Physics, and correlated areas. Via its SCTE::Instrument module, RS-232, USB, and LAN buses are supported, and the intricacies of hardware communication are encapsulated underneath an object oriented abstraction layer. Written in Perl, and using the SCPI protocol, enabled instruments can be easily programmed to perform a wide variety of tasks. While this work presents general aspects of the development of data acquisition systems using the SCTE framework, it is illustrated by particular applications designed for the calibration of several in-house developed devices for power measurement in the tokamak TCABR Alfvén Waves Excitement System. Catalogue identifier: AELZ_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AELZ_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: GNU General Public License Version 3 No. of lines in distributed program, including test data, etc.: 13 811 No. of bytes in distributed program, including test data, etc.: 743 709 Distribution format: tar.gz Programming language: Perl version 5.10.0 or higher. Computer: PC. SCPI capable digital oscilloscope, with RS-232, USB, or LAN communication ports, null modem, USB, or Ethernet cables Operating system: GNU/Linux (2.6.28-11), should also work on any Unix-based operational system Classification: 4.14 External routines: Perl modules: Device::SerialPort, Term::ANSIColor, Math::GSL, Net::HTTP. Gnuplot 4.0 or higher Nature of problem: Automation of experiments and data acquisition often requires expensive equipment and in-house development of software applications. Nowadays personal computers and test equipment come with fast and easy-to-use communication ports. Instrument vendors often supply application programs capable of controlling such devices, but are very restricted in terms of functionalities. For instance, they are not capable of controlling more than one test equipment at a same time or to automate repetitive tasks. SCTE provides a way of using auxiliary equipment in order to automate experiment procedures at low cost using only free, and open-source operational system and libraries. Solution method: SCTE provides a Perl module that implements RS-232, USB, and LAN communication allowing the use of SCPI capable instruments [1]. Therefore providing a straightforward way of creating automation and data acquisition applications using personal computers and testing instruments [2]. SCPI Consortium, Standard Commands for Programmable Instruments, 1999, http://www.scpiconsortium.org. L.C.B. Mostaço-Guidolin, Determinação da configuração de ondas de Alfvén excitadas no tokamak TCABR, Master's thesis, Universidade de São Paulo (2007), http://www.teses.usp.br/teses/disponiveis/43/43134/tde-23042009-230419/.

  3. Software for Better Documentation of Other Software

    NASA Technical Reports Server (NTRS)

    Pinedo, John

    2003-01-01

    The Literate Programming Extraction Engine is a Practical Extraction and Reporting Language- (PERL-)based computer program that facilitates and simplifies the implementation of a concept of self-documented literate programming in a fashion tailored to the typical needs of scientists. The advantage for the programmer is that documentation and source code are written side-by-side in the same file, reducing the likelihood that the documentation will be inconsistent with the code and improving the verification that the code performs its intended functions. The advantage for the user is the knowledge that the documentation matches the software because they come from the same file. This program unifies the documentation process for a variety of programming languages, including C, C++, and several versions of FORTRAN. This program can process the documentation in any markup language, and incorporates the LaTeX typesetting software. The program includes sample Makefile scripts for automating both the code-compilation (when appropriate) and documentation-generation processes into a single command-line statement. Also included are macro instructions for the Emacs display-editor software, making it easy for a programmer to toggle between editing in a code or a documentation mode.

  4. Foreign Language Analysis and Recognition (FLARe) Initial Progress

    DTIC Science & Technology

    2012-11-29

    University Language Modeling ToolKit CoMMA Count Mediated Morphological Analysis CRUD Create, Read , Update & Delete CPAN Comprehensive Perl Archive...DATES COVERED (From - To) 1 October 2010 – 30 September 2012 4. TITLE AND SUBTITLE Foreign Language Analysis and Recognition (FLARe) Initial Progress...AFRL-RH-WP-TR-2012-0165 FOREIGN LANGUAGE ANALYSIS AND RECOGNITION (FLARE) INITIAL PROGRESS Brian M. Ore

  5. Perl at the Joint Astronomy Centre

    NASA Astrophysics Data System (ADS)

    Jenness, Tim; Economou, Frossie; Tilanus, Remo P. J.; Best, Casey; Prestage, Richard M.; Shimek, Pam; Glazebrook, Karl; Farrell, Tony J.

    Perl is used extensively at the JAC (UKIRT and JCMT) and because of the language's flexibility (enabling us to interface perl to any library) we are finding that it is possible to write all of our utilities in it. This simplifies support and aids code reuse (via the module system and object oriented interface) as well as shortening development time. Currently we have developed interfaces to messaging systems (ADAM and DRAMA), I/O libraries (NDF, GSD), astronomical libraries (SLALIB) and the Starlink noticeboard system (NBS). We have also developed tools to aid in data taking (the JCMT observation desk) and data processing (surf and orac-dr) This paper will briefly review the facilities available, with an emphasis on those which might be of interest to other observatories.

  6. An interactive HTML ocean nowcast GUI based on Perl and JavaScript

    NASA Astrophysics Data System (ADS)

    Sakalaukus, Peter J.; Fox, Daniel N.; Louise Perkins, A.; Smedstad, Lucy F.

    1999-02-01

    We describe the use of Hyper Text Markup Language (HTML), JavaScript code, and Perl I/O to create and validate forms in an Internet-based graphical user interface (GUI) for the Naval Research Laboratory (NRL) Ocean models and Assimilation Demonstration System (NOMADS). The resulting nowcast system can be operated from any compatible browser across the Internet, for although the GUI was prepared in a Netscape browser, it used no Netscape extensions. Code available at: http://www.iamg.org/CGEditor/index.htm

  7. The Bio-Community Perl toolkit for microbial ecology.

    PubMed

    Angly, Florent E; Fields, Christopher J; Tyson, Gene W

    2014-07-01

    The development of bioinformatic solutions for microbial ecology in Perl is limited by the lack of modules to represent and manipulate microbial community profiles from amplicon and meta-omics studies. Here we introduce Bio-Community, an open-source, collaborative toolkit that extends BioPerl. Bio-Community interfaces with commonly used programs using various file formats, including BIOM, and provides operations such as rarefaction and taxonomic summaries. Bio-Community will help bioinformaticians to quickly piece together custom analysis pipelines and develop novel software. Availability an implementation: Bio-Community is cross-platform Perl code available from http://search.cpan.org/dist/Bio-Community under the Perl license. A readme file describes software installation and how to contribute. © The Author 2014. Published by Oxford University Press.

  8. ADASS Web Database XML Project

    NASA Astrophysics Data System (ADS)

    Barg, M. I.; Stobie, E. B.; Ferro, A. J.; O'Neil, E. J.

    In the spring of 2000, at the request of the ADASS Program Organizing Committee (POC), we began organizing information from previous ADASS conferences in an effort to create a centralized database. The beginnings of this database originated from data (invited speakers, participants, papers, etc.) extracted from HyperText Markup Language (HTML) documents from past ADASS host sites. Unfortunately, not all HTML documents are well formed and parsing them proved to be an iterative process. It was evident at the beginning that if these Web documents were organized in a standardized way, such as XML (Extensible Markup Language), the processing of this information across the Web could be automated, more efficient, and less error prone. This paper will briefly review the many programming tools available for processing XML, including Java, Perl and Python, and will explore the mapping of relational data from our MySQL database to XML.

  9. Resources for comparing the speed and performance of medical autocoders.

    PubMed

    Berman, Jules J

    2004-06-15

    Concept indexing is a popular method for characterizing medical text, and is one of the most important early steps in many data mining efforts. Concept indexing differs from simple word or phrase indexing because concepts are typically represented by a nomenclature code that binds a medical concept to all equivalent representations. A concept search on the term renal cell carcinoma would be expected to find occurrences of hypernephroma, and renal carcinoma (concept equivalents). The purpose of this study is to provide freely available resources to compare speed and performance among different autocoders. These tools consist of: 1) a public domain autocoder written in Perl (a free and open source programming language that installs on any operating system); 2) a nomenclature database derived from the unencumbered subset of the publicly available Unified Medical Language System; 3) a large corpus of autocoded output derived from a publicly available medical text. A simple lexical autocoder was written that parses plain-text into a listing of all 1,2,3, and 4-word strings contained in text, assigning a nomenclature code for text strings that match terms in the nomenclature. The nomenclature used is the unencumbered subset of the 2003 Unified Medical Language System (UMLS). The unencumbered subset of UMLS was reduced to exclude homonymous one-word terms and proper names, resulting in a term/code data dictionary containing about a half million medical terms. The Online Mendelian Inheritance in Man (OMIM), a 92+ Megabyte publicly available medical opus, was used as sample medical text for the autocoder. The autocoding Perl script is remarkably short, consisting of just 38 command lines. The 92+ Megabyte OMIM file was completely autocoded in 869 seconds on a 2.4 GHz processor (less than 10 seconds per Megabyte of text). The autocoded output file (9,540,442 bytes) contains 367,963 coded terms from OMIM and is distributed with this manuscript. A public domain Perl script is provided that can parse through plain-text files of any length, matching concepts against an external nomenclature. The script and associated files can be used freely to compare the speed and performance of autocoding software.

  10. Internet Distribution of Spacecraft Telemetry Data

    NASA Technical Reports Server (NTRS)

    Specht, Ted; Noble, David

    2006-01-01

    Remote Access Multi-mission Processing and Analysis Ground Environment (RAMPAGE) is a Java-language server computer program that enables near-real-time display of spacecraft telemetry data on any authorized client computer that has access to the Internet and is equipped with Web-browser software. In addition to providing a variety of displays of the latest available telemetry data, RAMPAGE can deliver notification of an alarm by electronic mail. Subscribers can then use RAMPAGE displays to determine the state of the spacecraft and formulate a response to the alarm, if necessary. A user can query spacecraft mission data in either binary or comma-separated-value format by use of a Web form or a Practical Extraction and Reporting Language (PERL) script to automate the query process. RAMPAGE runs on Linux and Solaris server computers in the Ground Data System (GDS) of NASA's Jet Propulsion Laboratory and includes components designed specifically to make it compatible with legacy GDS software. The client/server architecture of RAMPAGE and the use of the Java programming language make it possible to utilize a variety of competitive server and client computers, thereby also helping to minimize costs.

  11. Open-source framework for documentation of scientific software written on MATLAB-compatible programming languages

    NASA Astrophysics Data System (ADS)

    Konnik, Mikhail V.; Welsh, James

    2012-09-01

    Numerical simulators for adaptive optics systems have become an essential tool for the research and development of the future advanced astronomical instruments. However, growing software code of the numerical simulator makes it difficult to continue to support the code itself. The problem of adequate documentation of the astronomical software for adaptive optics simulators may complicate the development since the documentation must contain up-to-date schemes and mathematical descriptions implemented in the software code. Although most modern programming environments like MATLAB or Octave have in-built documentation abilities, they are often insufficient for the description of a typical adaptive optics simulator code. This paper describes a general cross-platform framework for the documentation of scientific software using open-source tools such as LATEX, mercurial, Doxygen, and Perl. Using the Perl script that translates M-files MATLAB comments into C-like, one can use Doxygen to generate and update the documentation for the scientific source code. The documentation generated by this framework contains the current code description with mathematical formulas, images, and bibliographical references. A detailed description of the framework components is presented as well as the guidelines for the framework deployment. Examples of the code documentation for the scripts and functions of a MATLAB-based adaptive optics simulator are provided.

  12. Using NetCloak to develop server-side Web-based experiments without writing CGI programs.

    PubMed

    Wolfe, Christopher R; Reyna, Valerie F

    2002-05-01

    Server-side experiments use the Web server, rather than the participant's browser, to handle tasks such as random assignment, eliminating inconsistencies with JAVA and other client-side applications. Heretofore, experimenters wishing to create server-side experiments have had to write programs to create common gateway interface (CGI) scripts in programming languages such as Perl and C++. NetCloak uses simple, HTML-like commands to create CGIs. We used NetCloak to implement an experiment on probability estimation. Measurements of time on task and participants' IP addresses assisted quality control. Without prior training, in less than 1 month, we were able to use NetCloak to design and create a Web-based experiment and to help graduate students create three Web-based experiments of their own.

  13. IRACproc: IRAC Post-BCD Processing

    NASA Astrophysics Data System (ADS)

    Schuster, Mike; Marengo, Massimo; Patten, Brian

    2012-09-01

    IRACproc is a software suite that facilitates the co-addition of dithered or mapped Spitzer/IRAC data to make them ready for further analysis with application to a wide variety of IRAC observing programs. The software runs within PDL, a numeric extension for Perl available from pdl.perl.org, and as stand alone perl scripts. In acting as a wrapper for the Spitzer Science Center's MOPEX software, IRACproc improves the rejection of cosmic rays and other transients in the co-added data. In addition, IRACproc performs (optional) Point Spread Function (PSF) fitting, subtraction, and masking of saturated stars.

  14. Detecting distant homologies on protozoans metabolic pathways using scientific workflows.

    PubMed

    da Cruz, Sérgio Manuel Serra; Batista, Vanessa; Silva, Edno; Tosta, Frederico; Vilela, Clarissa; Cuadrat, Rafael; Tschoeke, Diogo; Dávila, Alberto M R; Campos, Maria Luiza Machado; Mattoso, Marta

    2010-01-01

    Bioinformatics experiments are typically composed of programs in pipelines manipulating an enormous quantity of data. An interesting approach for managing those experiments is through workflow management systems (WfMS). In this work we discuss WfMS features to support genome homology workflows and present some relevant issues for typical genomic experiments. Our evaluation used Kepler WfMS to manage a real genomic pipeline, named OrthoSearch, originally defined as a Perl script. We show a case study detecting distant homologies on trypanomatids metabolic pathways. Our results reinforce the benefits of WfMS over script languages and point out challenges to WfMS in distributed environments.

  15. Tools for automating spacecraft ground systems: The Intelligent Command and Control (ICC) approach

    NASA Technical Reports Server (NTRS)

    Stoffel, A. William; Mclean, David

    1996-01-01

    The practical application of scripting languages and World Wide Web tools to the support of spacecraft ground system automation, is reported on. The mission activities and the automation tools used at the Goddard Space Flight Center (MD) are reviewed. The use of the Tool Command Language (TCL) and the Practical Extraction and Report Language (PERL) scripting tools for automating mission operations is discussed together with the application of different tools for the Compton Gamma Ray Observatory ground system.

  16. Cell illustrator 4.0: a computational platform for systems biology.

    PubMed

    Nagasaki, Masao; Saito, Ayumu; Jeong, Euna; Li, Chen; Kojima, Kaname; Ikeda, Emi; Miyano, Satoru

    2011-01-01

    Cell Illustrator is a software platform for Systems Biology that uses the concept of Petri net for modeling and simulating biopathways. It is intended for biological scientists working at bench. The latest version of Cell Illustrator 4.0 uses Java Web Start technology and is enhanced with new capabilities, including: automatic graph grid layout algorithms using ontology information; tools using Cell System Markup Language (CSML) 3.0 and Cell System Ontology 3.0; parameter search module; high-performance simulation module; CSML database management system; conversion from CSML model to programming languages (FORTRAN, C, C++, Java, Python and Perl); import from SBML, CellML, and BioPAX; and, export to SVG and HTML. Cell Illustrator employs an extension of hybrid Petri net in an object-oriented style so that biopathway models can include objects such as DNA sequence, molecular density, 3D localization information, transcription with frame-shift, translation with codon table, as well as biochemical reactions.

  17. Cell Illustrator 4.0: a computational platform for systems biology.

    PubMed

    Nagasaki, Masao; Saito, Ayumu; Jeong, Euna; Li, Chen; Kojima, Kaname; Ikeda, Emi; Miyano, Satoru

    2010-01-01

    Cell Illustrator is a software platform for Systems Biology that uses the concept of Petri net for modeling and simulating biopathways. It is intended for biological scientists working at bench. The latest version of Cell Illustrator 4.0 uses Java Web Start technology and is enhanced with new capabilities, including: automatic graph grid layout algorithms using ontology information; tools using Cell System Markup Language (CSML) 3.0 and Cell System Ontology 3.0; parameter search module; high-performance simulation module; CSML database management system; conversion from CSML model to programming languages (FORTRAN, C, C++, Java, Python and Perl); import from SBML, CellML, and BioPAX; and, export to SVG and HTML. Cell Illustrator employs an extension of hybrid Petri net in an object-oriented style so that biopathway models can include objects such as DNA sequence, molecular density, 3D localization information, transcription with frame-shift, translation with codon table, as well as biochemical reactions.

  18. An Investigation of How ESL Students Write.

    ERIC Educational Resources Information Center

    Raimes, Ann

    A study is described which investigated the differences between English-as-a-second-language (ESL) writers and native-English-speaking writers and examined closely a range of ESL writers and their composing processes. The procedures used were those used by Sondra Perl in a study of the composing processes of unskilled college writers (1979).…

  19. Lambert W function for applications in physics

    NASA Astrophysics Data System (ADS)

    Veberič, Darko

    2012-12-01

    The Lambert W(x) function and its possible applications in physics are presented. The actual numerical implementation in C++ consists of Halley's and Fritsch's iterations with initial approximations based on branch-point expansion, asymptotic series, rational fits, and continued-logarithm recursion. Program summaryProgram title: LambertW Catalogue identifier: AENC_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AENC_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: GNU General Public License version 3 No. of lines in distributed program, including test data, etc.: 1335 No. of bytes in distributed program, including test data, etc.: 25 283 Distribution format: tar.gz Programming language: C++ (with suitable wrappers it can be called from C, Fortran etc.), the supplied command-line utility is suitable for other scripting languages like sh, csh, awk, perl etc. Computer: All systems with a C++ compiler. Operating system: All Unix flavors, Windows. It might work with others. RAM: Small memory footprint, less than 1 MB Classification: 1.1, 4.7, 11.3, 11.9. Nature of problem: Find fast and accurate numerical implementation for the Lambert W function. Solution method: Halley's and Fritsch's iterations with initial approximations based on branch-point expansion, asymptotic series, rational fits, and continued logarithm recursion. Additional comments: Distribution file contains the command-line utility lambert-w. Doxygen comments, included in the source files. Makefile. Running time: The tests provided take only a few seconds to run.

  20. Production code control system for hydrodynamics simulations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Slone, D.M.

    1997-08-18

    We describe how the Production Code Control System (pCCS), written in Perl, has been used to control and monitor the execution of a large hydrodynamics simulation code in a production environment. We have been able to integrate new, disparate, and often independent, applications into the PCCS framework without the need to modify any of our existing application codes. Both users and code developers see a consistent interface to the simulation code and associated applications regardless of the physical platform, whether an MPP, SMP, server, or desktop workstation. We will also describe our use of Perl to develop a configuration managementmore » system for the simulation code, as well as a code usage database and report generator. We used Perl to write a backplane that allows us plug in preprocessors, the hydrocode, postprocessors, visualization tools, persistent storage requests, and other codes. We need only teach PCCS a minimal amount about any new tool or code to essentially plug it in and make it usable to the hydrocode. PCCS has made it easier to link together disparate codes, since using Perl has removed the need to learn the idiosyncrasies of system or RPC programming. The text handling in Perl makes it easy to teach PCCS about new codes, or changes to existing codes.« less

  1. Mercury Shopping Cart Interface

    NASA Technical Reports Server (NTRS)

    Pfister, Robin; McMahon, Joe

    2006-01-01

    Mercury Shopping Cart Interface (MSCI) is a reusable component of the Power User Interface 5.0 (PUI) program described in another article. MSCI is a means of encapsulating the logic and information needed to describe an orderable item consistent with Mercury Shopping Cart service protocol. Designed to be used with Web-browser software, MSCI generates Hypertext Markup Language (HTML) pages on which ordering information can be entered. MSCI comprises two types of Practical Extraction and Report Language (PERL) modules: template modules and shopping-cart logic modules. Template modules generate HTML pages for entering the required ordering details and enable submission of the order via a Hypertext Transfer Protocol (HTTP) post. Shopping cart modules encapsulate the logic and data needed to describe an individual orderable item to the Mercury Shopping Cart service. These modules evaluate information entered by the user to determine whether it is sufficient for the Shopping Cart service to process the order. Once an order has been passed from MSCI to a deployed Mercury Shopping Cart server, there is no further interaction with the user.

  2. Generating and Executing Complex Natural Language Queries across Linked Data.

    PubMed

    Hamon, Thierry; Mougin, Fleur; Grabar, Natalia

    2015-01-01

    With the recent and intensive research in the biomedical area, the knowledge accumulated is disseminated through various knowledge bases. Links between these knowledge bases are needed in order to use them jointly. Linked Data, SPARQL language, and interfaces in Natural Language question-answering provide interesting solutions for querying such knowledge bases. We propose a method for translating natural language questions in SPARQL queries. We use Natural Language Processing tools, semantic resources, and the RDF triples description. The method is designed on 50 questions over 3 biomedical knowledge bases, and evaluated on 27 questions. It achieves 0.78 F-measure on the test set. The method for translating natural language questions into SPARQL queries is implemented as Perl module available at http://search.cpan.org/ thhamon/RDF-NLP-SPARQLQuery.

  3. Dynamic online surveys and experiments with the free open-source software dynQuest.

    PubMed

    Rademacher, Jens D M; Lippke, Sonia

    2007-08-01

    With computers and the World Wide Web widely available, collecting data through Web browsers is an attractive method utilized by the social sciences. In this article, conducting PC- and Web-based trials with the software package dynQuest is described. The software manages dynamic questionnaire-based trials over the Internet or on single computers, possibly as randomized control trials (RCT), if two or more groups are involved. The choice of follow-up questions can depend on previous responses, as needed for matched interventions. Data are collected in a simple text-based database that can be imported easily into other programs for postprocessing and statistical analysis. The software consists of platform-independent scripts written in the programming language PERL that use the common gateway interface between Web browser and server for submission of data through HTML forms. Advantages of dynQuest are parsimony, simplicity in use and installation, transparency, and reliability. The program is available as open-source freeware from the authors.

  4. Perl Modules for Constructing Iterators

    NASA Technical Reports Server (NTRS)

    Tilmes, Curt

    2009-01-01

    The Iterator Perl Module provides a general-purpose framework for constructing iterator objects within Perl, and a standard API for interacting with those objects. Iterators are an object-oriented design pattern where a description of a series of values is used in a constructor. Subsequent queries can request values in that series. These Perl modules build on the standard Iterator framework and provide iterators for some other types of values. Iterator::DateTime constructs iterators from DateTime objects or Date::Parse descriptions and ICal/RFC 2445 style re-currence descriptions. It supports a variety of input parameters, including a start to the sequence, an end to the sequence, an Ical/RFC 2445 recurrence describing the frequency of the values in the series, and a format description that can refine the presentation manner of the DateTime. Iterator::String constructs iterators from string representations. This module is useful in contexts where the API consists of supplying a string and getting back an iterator where the specific iteration desired is opaque to the caller. It is of particular value to the Iterator::Hash module which provides nested iterations. Iterator::Hash constructs iterators from Perl hashes that can include multiple iterators. The constructed iterators will return all the permutations of the iterations of the hash by nested iteration of embedded iterators. A hash simply includes a set of keys mapped to values. It is a very common data structure used throughout Perl programming. The Iterator:: Hash module allows a hash to include strings defining iterators (parsed and dispatched with Iterator::String) that are used to construct an overall series of hash values.

  5. Web-based data acquisition and management system for GOSAT validation Lidar data analysis

    NASA Astrophysics Data System (ADS)

    Okumura, Hiroshi; Takubo, Shoichiro; Kawasaki, Takeru; Abdullah, Indra N.; Uchino, Osamu; Morino, Isamu; Yokota, Tatsuya; Nagai, Tomohiro; Sakai, Tetsu; Maki, Takashi; Arai, Kohei

    2012-11-01

    An web-base data acquisition and management system for GOSAT (Greenhouse gases Observation SATellite) validation lidar data analysis is developed. The system consists of data acquisition sub-system (DAS) and data management sub-system (DMS). DAS written in Perl language acquires AMeDAS ground-level meteorological data, Rawinsonde upper-air meteorological data, ground-level oxidant data, skyradiometer data, skyview camera images, meteorological satellite IR image data and GOSAT validation lidar data. DMS written in PHP language demonstrates satellite-pass date and all acquired data.

  6. Learning SAS’s Perl Regular Expression Matching the Easy Way: By Doing

    DTIC Science & Technology

    2015-01-12

    Doing 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Paul Genovesi 5d. PROJECT NUMBER 5e. TASK NUMBER 5f...regex_learning_tool allows both beginner and expert to efficiently practice PRX matching by selecting and processing only the match records that the user is interested...perl regular expression and/or source string. The regex_learning_tool allows both beginner and expert to efficiently practice PRX matching by

  7. Automated radiotherapy treatment plan integrity verification

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yang Deshan; Moore, Kevin L.

    2012-03-15

    Purpose: In our clinic, physicists spend from 15 to 60 min to verify the physical and dosimetric integrity of radiotherapy plans before presentation to radiation oncology physicians for approval. The purpose of this study was to design and implement a framework to automate as many elements of this quality control (QC) step as possible. Methods: A comprehensive computer application was developed to carry out a majority of these verification tasks in the Philips PINNACLE treatment planning system (TPS). This QC tool functions based on both PINNACLE scripting elements and PERL sub-routines. The core of this technique is the method ofmore » dynamic scripting, which involves a PERL programming module that is flexible and powerful for treatment plan data handling. Run-time plan data are collected, saved into temporary files, and analyzed against standard values and predefined logical rules. The results were summarized in a hypertext markup language (HTML) report that is displayed to the user. Results: This tool has been in clinical use for over a year. The occurrence frequency of technical problems, which would cause delays and suboptimal plans, has been reduced since clinical implementation. Conclusions: In addition to drastically reducing the set of human-driven logical comparisons, this QC tool also accomplished some tasks that are otherwise either quite laborious or impractical for humans to verify, e.g., identifying conflicts amongst IMRT optimization objectives.« less

  8. MK3TOOLS & NetCDF - storing VLBI data in a machine independent array oriented data format

    NASA Astrophysics Data System (ADS)

    Hobiger, T.; Koyama, Y.; Kondo, T.

    2007-07-01

    In the beginning of 2002 the International VLBI Service (IVS) has agreed to introduce a Platform-independent VLBI exchange format (PIVEX) which permits the exchange of observational data and stimulates the research across different analysis groups. Unfortunately PIVEX has never been implemented and many analysis software packages are still depending on prior processing (e.g. ambiguity resolution and computation of ionosphere corrections) done by CALC/SOLVE. Thus MK3TOOLS which handles MK3 databases without CALC/SOLVE being installed has been developed. It uses the NetCDF format to store the data and since interfaces exist for a variety of programming languages (FORTRAN, C/C++, JAVA, Perl, Python) it can be easily incorporated in existing and upcoming analysis software packages.

  9. ViralEpi v1.0: a high-throughput spectrum of viral epigenomic methylation profiles from diverse diseases.

    PubMed

    Khan, Mohd Shoaib; Gupta, Amit Kumar; Kumar, Manoj

    2016-01-01

    To develop a computational resource for viral epigenomic methylation profiles from diverse diseases. Methylation patterns of Epstein-Barr virus and hepatitis B virus genomic regions are provided as web platform developed using open source Linux-Apache-MySQL-PHP (LAMP) bundle: programming and scripting languages, that is, HTML, JavaScript and PERL. A comprehensive and integrated web resource ViralEpi v1.0 is developed providing well-organized compendium of methylation events and statistical analysis associated with several diseases. Additionally, it also facilitates 'Viral EpiGenome Browser' for user-affable browsing experience using JavaScript-based JBrowse. This web resource would be helpful for research community engaged in studying epigenetic biomarkers for appropriate prognosis and diagnosis of diseases and its various stages.

  10. GenomeVista

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Poliakov, Alexander; Couronne, Olivier

    2002-11-04

    Aligning large vertebrate genomes that are structurally complex poses a variety of problems not encountered on smaller scales. Such genomes are rich in repetitive elements and contain multiple segmental duplications, which increases the difficulty of identifying true orthologous SNA segments in alignments. The sizes of the sequences make many alignment algorithms designed for comparing single proteins extremely inefficient when processing large genomic intervals. We integrated both local and global alignment tools and developed a suite of programs for automatically aligning large vertebrate genomes and identifying conserved non-coding regions in the alignments. Our method uses the BLAT local alignment program tomore » find anchors on the base genome to identify regions of possible homology for a query sequence. These regions are postprocessed to find the best candidates which are then globally aligned using the AVID global alignment program. In the last step conserved non-coding segments are identified using VISTA. Our methods are fast and the resulting alignments exhibit a high degree of sensitivity, covering more than 90% of known coding exons in the human genome. The GenomeVISTA software is a suite of Perl programs that is built on a MySQL database platform. The scheduler gets control data from the database, builds a queve of jobs, and dispatches them to a PC cluster for execution. The main program, running on each node of the cluster, processes individual sequences. A Perl library acts as an interface between the database and the above programs. The use of a separate library allows the programs to function independently of the database schema. The library also improves on the standard Perl MySQL database interfere package by providing auto-reconnect functionality and improved error handling.« less

  11. Maneuver Automation Software

    NASA Technical Reports Server (NTRS)

    Uffelman, Hal; Goodson, Troy; Pellegrin, Michael; Stavert, Lynn; Burk, Thomas; Beach, David; Signorelli, Joel; Jones, Jeremy; Hahn, Yungsun; Attiyah, Ahlam; hide

    2009-01-01

    The Maneuver Automation Software (MAS) automates the process of generating commands for maneuvers to keep the spacecraft of the Cassini-Huygens mission on a predetermined prime mission trajectory. Before MAS became available, a team of approximately 10 members had to work about two weeks to design, test, and implement each maneuver in a process that involved running many maneuver-related application programs and then serially handing off data products to other parts of the team. MAS enables a three-member team to design, test, and implement a maneuver in about one-half hour after Navigation has process-tracking data. MAS accepts more than 60 parameters and 22 files as input directly from users. MAS consists of Practical Extraction and Reporting Language (PERL) scripts that link, sequence, and execute the maneuver- related application programs: "Pushing a single button" on a graphical user interface causes MAS to run navigation programs that design a maneuver; programs that create sequences of commands to execute the maneuver on the spacecraft; and a program that generates predictions about maneuver performance and generates reports and other files that enable users to quickly review and verify the maneuver design. MAS can also generate presentation materials, initiate electronic command request forms, and archive all data products for future reference.

  12. Programmatic access to data and information at the IRIS DMC via web services

    NASA Astrophysics Data System (ADS)

    Weertman, B. R.; Trabant, C.; Karstens, R.; Suleiman, Y. Y.; Ahern, T. K.; Casey, R.; Benson, R. B.

    2011-12-01

    The IRIS Data Management Center (DMC) has developed a suite of web services that provide access to the DMC's time series holdings, their related metadata and earthquake catalogs. In addition, services are available to perform simple, on-demand time series processing at the DMC prior to being shipped to the user. The primary goal is to provide programmatic access to data and processing services in a manner usable by and useful to the research community. The web services are relatively simple to understand and use and will form the foundation on which future DMC access tools will be built. Based on standard Web technologies they can be accessed programmatically with a wide range of programming languages (e.g. Perl, Python, Java), command line utilities such as wget and curl or with any web browser. We anticipate these services being used for everything from simple command line access, used in shell scripts and higher programming languages to being integrated within complex data processing software. In addition to improving access to our data by the seismological community the web services will also make our data more accessible to other disciplines. The web services available from the DMC include ws-bulkdataselect for the retrieval of large volumes of miniSEED data, ws-timeseries for the retrieval of individual segments of time series data in a variety of formats (miniSEED, SAC, ASCII, audio WAVE, and PNG plots) with optional signal processing, ws-station for station metadata in StationXML format, ws-resp for the retrieval of instrument response in RESP format, ws-sacpz for the retrieval of sensor response in the SAC poles and zeros convention and ws-event for the retrieval of earthquake catalogs. To make the services even easier to use, the DMC is developing a library that allows Java programmers to seamlessly retrieve and integrate DMC information into their own programs. The library will handle all aspects of dealing with the services and will parse the returned data. By using this library a developer will not need to learn the details of the service interfaces or understand the data formats returned. This library will be used to build the software bridge needed to request data and information from within MATLAB°. We also provide several client scripts written in Perl for the retrieval of waveform data, metadata and earthquake catalogs using command line programs. For more information on the DMC's web services please visit http://www.iris.edu/ws/

  13. Perls with Gloria Re-reviewed: Gestalt Techniques and Perls's Practices.

    ERIC Educational Resources Information Center

    Dolliver, Robert H.

    1991-01-01

    Reviews the filmed interview with Gloria by Perls (1965) which demonstrated some standard Gestalt therapy techniques and presents examples from film. Identifies discrepancies between Perls's description of Gestalt therapeutic processes and his interview behavior. Makes reflections on the inherent difficulties with the concept of the emerging…

  14. Neuro-Linguistic Programming: The New Eclectic Therapy.

    ERIC Educational Resources Information Center

    Betts, Nicoletta C.

    Richard Bandler and John Grinder developed neuro-linguisitc programming (NLP) after observing "the magical skills of potent psychotherapists" Frederick Perls, Virginia Satir, and Milton Erikson. They compiled the most effective techniques for building rapport, gathering data, and influencing change in psychotherapy, offering them only as…

  15. IT Resources - Betty Petersen Memorial Library

    Science.gov Websites

    Available NOAA-wide. Note: This link takes you to a nonfederal website. Guide for usage Apress.com Free eBooks Free eBooks available through Apress publishers. Topics include PHP, Perl, and programming VB .Net . Note: This link takes you to a nonfederal website. Online Programming Books Free programming books

  16. Geospatial Authentication

    NASA Technical Reports Server (NTRS)

    Lyle, Stacey D.

    2009-01-01

    A software package that has been designed to allow authentication for determining if the rover(s) is/are within a set of boundaries or a specific area to access critical geospatial information by using GPS signal structures as a means to authenticate mobile devices into a network wirelessly and in real-time has been developed. The advantage lies in that the system only allows those with designated geospatial boundaries or areas into the server. The Geospatial Authentication software has two parts Server and Client. The server software is a virtual private network (VPN) developed in Linux operating system using Perl programming language. The server can be a stand-alone VPN server or can be combined with other applications and services. The client software is a GUI Windows CE software, or Mobile Graphical Software, that allows users to authenticate into a network. The purpose of the client software is to pass the needed satellite information to the server for authentication.

  17. RNA-Seq-Based Transcript Structure Analysis with TrBorderExt.

    PubMed

    Wang, Yejun; Sun, Ming-An; White, Aaron P

    2018-01-01

    RNA-Seq has become a routine strategy for genome-wide gene expression comparisons in bacteria. Despite lower resolution in transcript border parsing compared with dRNA-Seq, TSS-EMOTE, Cappable-seq, Term-seq, and others, directional RNA-Seq still illustrates its advantages: low cost, quantification and transcript border analysis with a medium resolution (±10-20 nt). To facilitate mining of directional RNA-Seq datasets especially with respect to transcript structure analysis, we developed a tool, TrBorderExt, which can parse transcript start sites and termination sites accurately in bacteria. A detailed protocol is described in this chapter for how to use the software package step by step to identify bacterial transcript borders from raw RNA-Seq data. The package was developed with Perl and R programming languages, and is accessible freely through the website: http://www.szu-bioinf.org/TrBorderExt .

  18. Jamaica: a middle-aged program searches for new horizons.

    PubMed

    1984-01-01

    The advertising and marketing consultant for Jamaica's Commercial Distribution of Contraceptives (JCDC) program, states that the program has reached a state of maturity that has resulted in some inertia. Although still the leader among contraceptive social marketing (CSM) programs in reaching the greatest percentage of its target market, product sales are no longer on an upswing, and retail outlets are not increasing in number. The project is hoping that the introduction of a new thin condom can help, but more than 1 new product may be needed to recapture momentum. The JCDC began in 1974 when Westinghouse Health Systems won a 3 year Agency for International Development (AID) award to create a Jamaican CSM program. Challenges facing the new social marketing project included: oral contraceptives (OCs) were sold only by prescription; most pharmacies were located in urban areas; many consumers associated condoms with prostitution and disease; and retailers were reluctant to carry contraceptives and ignorant of OC side effects. The 1st breakthrough came when Westinghouse obtained government permission to sell a project pill without prescription. After market research, project managers chose the name "Perle" for the JCDC's pill, manufactured in the US by Syntex as Noriday. "Panther" became the project's condom. Prices were set at US17 cents for a Panther 3-pack and 34 cents for a Perle cycle. Advertising messages appeared on television, radio, bus shelters, cinema screens, billboards, and point of purchase displays. By the end of the 1st year's sales, a soft goods manufacturer had asked permission to produce Panther T-shirts and a Reggae composer had popularized songs about the product. Such promotional tactics boosted sales of all contraceptives on the island. About 690,000 Panther condoms and 450,000 other brands were sold in 1976; 195,000 Perle cycles were purchased compared with 135,000 cycles for all other brands combined. By 1977, Westinghouse was reducing advertising and concentrating on expanding retail sales outlets. Panther was being sold through 1108 outlets; Perle was distributed via 267 predominantly pharmacy outlets. In 1977 AID's contract with Westinghouse ended and the Jamaican National Family Planning Board took over the project management. With its subsidy markedly reduced, the JCDC soon was experiencing difficulty in Jamaica's troubled economy; as well as difficulty in expanding sales outlet. Despite the project's financial pinch, the JCDC has -- with some success -- used imaginative tactics like contests to spur sales.

  19. Software Assurance Measurement -- State of the Practice

    DTIC Science & Technology

    2013-11-01

    quality and productivity. 30+ languages, C/C++, Java , .NET, Oracle, PeopleSoft, SAP, Siebel, Spring, Struts, Hibernate , and all major databases. ChecKing...NET 39 ActionScript 39 Ada 40 C/C++ 40 Java 41 JavaScript 42 Objective-C 42 Opa 42 Packages 42 Perl 42 PHP 42 Python 42 Formal Methods...Suite—A tool for Ada, C, C++, C#, and Java code that comprises various analyses such as architecture checking, interface analyses, and clone detection

  20. PanWeb: A web interface for pan-genomic analysis.

    PubMed

    Pantoja, Yan; Pinheiro, Kenny; Veras, Allan; Araújo, Fabrício; Lopes de Sousa, Ailton; Guimarães, Luis Carlos; Silva, Artur; Ramos, Rommel T J

    2017-01-01

    With increased production of genomic data since the advent of next-generation sequencing (NGS), there has been a need to develop new bioinformatics tools and areas, such as comparative genomics. In comparative genomics, the genetic material of an organism is directly compared to that of another organism to better understand biological species. Moreover, the exponentially growing number of deposited prokaryote genomes has enabled the investigation of several genomic characteristics that are intrinsic to certain species. Thus, a new approach to comparative genomics, termed pan-genomics, was developed. In pan-genomics, various organisms of the same species or genus are compared. Currently, there are many tools that can perform pan-genomic analyses, such as PGAP (Pan-Genome Analysis Pipeline), Panseq (Pan-Genome Sequence Analysis Program) and PGAT (Prokaryotic Genome Analysis Tool). Among these software tools, PGAP was developed in the Perl scripting language and its reliance on UNIX platform terminals and its requirement for an extensive parameterized command line can become a problem for users without previous computational knowledge. Thus, the aim of this study was to develop a web application, known as PanWeb, that serves as a graphical interface for PGAP. In addition, using the output files of the PGAP pipeline, the application generates graphics using custom-developed scripts in the R programming language. PanWeb is freely available at http://www.computationalbiology.ufpa.br/panweb.

  1. Software for Managing Parametric Studies

    NASA Technical Reports Server (NTRS)

    Yarrow, Maurice; McCann, Karen M.; DeVivo, Adrian

    2003-01-01

    The Information Power Grid Virtual Laboratory (ILab) is a Practical Extraction and Reporting Language (PERL) graphical-user-interface computer program that generates shell scripts to facilitate parametric studies performed on the Grid. (The Grid denotes a worldwide network of supercomputers used for scientific and engineering computations involving data sets too large to fit on desktop computers.) Heretofore, parametric studies on the Grid have been impeded by the need to create control language scripts and edit input data files painstaking tasks that are necessary for managing multiple jobs on multiple computers. ILab reflects an object-oriented approach to automation of these tasks: All data and operations are organized into packages in order to accelerate development and debugging. A container or document object in ILab, called an experiment, contains all the information (data and file paths) necessary to define a complex series of repeated, sequenced, and/or branching processes. For convenience and to enable reuse, this object is serialized to and from disk storage. At run time, the current ILab experiment is used to generate required input files and shell scripts, create directories, copy data files, and then both initiate and monitor the execution of all computational processes.

  2. Master Metadata Repository and Metadata-Management System

    NASA Technical Reports Server (NTRS)

    Armstrong, Edward; Reed, Nate; Zhang, Wen

    2007-01-01

    A master metadata repository (MMR) software system manages the storage and searching of metadata pertaining to data from national and international satellite sources of the Global Ocean Data Assimilation Experiment (GODAE) High Resolution Sea Surface Temperature Pilot Project [GHRSSTPP]. These sources produce a total of hundreds of data files daily, each file classified as one of more than ten data products representing global sea-surface temperatures. The MMR is a relational database wherein the metadata are divided into granulelevel records [denoted file records (FRs)] for individual satellite files and collection-level records [denoted data set descriptions (DSDs)] that describe metadata common to all the files from a specific data product. FRs and DSDs adhere to the NASA Directory Interchange Format (DIF). The FRs and DSDs are contained in separate subdatabases linked by a common field. The MMR is configured in MySQL database software with custom Practical Extraction and Reporting Language (PERL) programs to validate and ingest the metadata records. The database contents are converted into the Federal Geographic Data Committee (FGDC) standard format by use of the Extensible Markup Language (XML). A Web interface enables users to search for availability of data from all sources.

  3. Improvement of the software Bernese for SLR data processing in the Main Metrological Centre of the State Time and Frequency Service

    NASA Astrophysics Data System (ADS)

    Tsyba, E.; Kaufman, M.

    2015-08-01

    Preparatory works for resuming operational calculations of the Earth rotation parameters based on the results of satellite laser ranging data processing (LAGEOS 1, LAGEOS 2) are to be completed in the Main Metrology Centre Of The State Time And Frequency Service (VNIIFTRI) in 2014. For this purpose BERNESE 5.2 software (Dach & Walser, 2014) was chosen as a base software which has been used for many years in the Main Metrological Centre of the State Time and Frequency Service to process phase observations of GLONASS and GPS satellites. Although in the BERNESE 5.2 software announced presentation the possibility of the SLR data processing is declared, it has not been fully implemented. In particular there is no such an essential element as corrective action (as input or resulting parameters) in the local time scale ("time bias"), etc. Therefore, additional program blocks have been developed and integrated into the BERNESE 5.2 software environment. The program blocks are written in Perl and Matlab program languages and can be used both for Windows and Linux, 32-bit and 64-bit platforms.

  4. i-ADHoRe 2.0: an improved tool to detect degenerated genomic homology using genomic profiles.

    PubMed

    Simillion, Cedric; Janssens, Koen; Sterck, Lieven; Van de Peer, Yves

    2008-01-01

    i-ADHoRe is a software tool that combines gene content and gene order information of homologous genomic segments into profiles to detect highly degenerated homology relations within and between genomes. The new version offers, besides a significant increase in performance, several optimizations to the algorithm, most importantly to the profile alignment routine. As a result, the annotations of multiple genomes, or parts thereof, can be fed simultaneously into the program, after which it will report all regions of homology, both within and between genomes. The i-ADHoRe 2.0 package contains the C++ source code for the main program as well as various Perl scripts and a fully documented Perl API to facilitate post-processing. The software runs on any Linux- or -UNIX based platform. The package is freely available for academic users and can be downloaded from http://bioinformatics.psb.ugent.be/

  5. Analyzing multiple data sets by interconnecting RSAT programs via SOAP Web services: an example with ChIP-chip data.

    PubMed

    Sand, Olivier; Thomas-Chollier, Morgane; Vervisch, Eric; van Helden, Jacques

    2008-01-01

    This protocol shows how to access the Regulatory Sequence Analysis Tools (RSAT) via a programmatic interface in order to automate the analysis of multiple data sets. We describe the steps for writing a Perl client that connects to the RSAT Web services and implements a workflow to discover putative cis-acting elements in promoters of gene clusters. In the presented example, we apply this workflow to lists of transcription factor target genes resulting from ChIP-chip experiments. For each factor, the protocol predicts the binding motifs by detecting significantly overrepresented hexanucleotides in the target promoters and generates a feature map that displays the positions of putative binding sites along the promoter sequences. This protocol is addressed to bioinformaticians and biologists with programming skills (notions of Perl). Running time is approximately 6 min on the example data set.

  6. HackaMol: An Object-Oriented Modern Perl Library for Molecular Hacking on Multiple Scales

    DOE PAGES

    Riccardi, Demian M.; Parks, Jerry M.; Johs, Alexander; ...

    2015-03-20

    HackaMol is an open source, object-oriented toolkit written in Modern Perl that organizes atoms within molecules and provides chemically intuitive attributes and methods. The library consists of two components: HackaMol, the core that contains classes for storing and manipulating molecular information, and HackaMol::X, the extensions that use the core. We tested the core; it is well-documented and easy to install across computational platforms. Our goal for the extensions is to provide a more flexible space for researchers to develop and share new methods. In this application note, we provide a description of the core classes and two extensions: HackaMol::X::Calculator, anmore » abstract calculator that uses code references to generalize interfaces with external programs, and HackaMol::X::Vina, a structured class that provides an interface with the AutoDock Vina docking program.« less

  7. HackaMol: An Object-Oriented Modern Perl Library for Molecular Hacking on Multiple Scales.

    PubMed

    Riccardi, Demian; Parks, Jerry M; Johs, Alexander; Smith, Jeremy C

    2015-04-27

    HackaMol is an open source, object-oriented toolkit written in Modern Perl that organizes atoms within molecules and provides chemically intuitive attributes and methods. The library consists of two components: HackaMol, the core that contains classes for storing and manipulating molecular information, and HackaMol::X, the extensions that use the core. The core is well-tested, well-documented, and easy to install across computational platforms. The goal of the extensions is to provide a more flexible space for researchers to develop and share new methods. In this application note, we provide a description of the core classes and two extensions: HackaMol::X::Calculator, an abstract calculator that uses code references to generalize interfaces with external programs, and HackaMol::X::Vina, a structured class that provides an interface with the AutoDock Vina docking program.

  8. HackaMol: An Object-Oriented Modern Perl Library for Molecular Hacking on Multiple Scales

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Riccardi, Demian M.; Parks, Jerry M.; Johs, Alexander

    HackaMol is an open source, object-oriented toolkit written in Modern Perl that organizes atoms within molecules and provides chemically intuitive attributes and methods. The library consists of two components: HackaMol, the core that contains classes for storing and manipulating molecular information, and HackaMol::X, the extensions that use the core. We tested the core; it is well-documented and easy to install across computational platforms. Our goal for the extensions is to provide a more flexible space for researchers to develop and share new methods. In this application note, we provide a description of the core classes and two extensions: HackaMol::X::Calculator, anmore » abstract calculator that uses code references to generalize interfaces with external programs, and HackaMol::X::Vina, a structured class that provides an interface with the AutoDock Vina docking program.« less

  9. SNS Proton Beam Window Disposal

    NASA Astrophysics Data System (ADS)

    Popova, Irina; Gallmeier, Franz X.; Trotter, Steven

    2017-09-01

    In order to support the disposal of the proton beam window assembly of the Spallation Neutron Source beamline to the target station, waste classification analyses are performed. The window has a limited life-time due to radiation-induced material damage. Analyses include calculation of the radionuclide inventory and shielding analyses for the transport package/container to ensure that the container is compliant with the transportation and waste management regulations. In order to automate this procedure and minimize manual work a script in Perl language was written.

  10. Placing pain on the sensory map: classic papers by Ed Perl and colleagues.

    PubMed

    Mason, Peggy

    2007-03-01

    This essay looks at two papers published by Ed Perl and co-workers that identified specifically nociceptive neurons in the periphery and superficial dorsal horn. Bessou P and Perl ER. Response of cutaneous sensory units with unmyelinated fibers to noxious stimuli. J Neurophysiol 32: 1025-1043 1969. Christensen BN and Perl ER. Spinal neurons specifically excited by noxious or thermal stimuli: marginal zone of the dorsal horn. J Neurophysiol 33: 293-307 1970.

  11. Perl Embedded in PTC's Pro/ENGINEER, Version 1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    2003-12-22

    Pro-PERL (AKA Pro/PERL) is a Perl extension to the PTC Pro/TOOLKIT API to the PTC Pro/ENGINEER CAD application including an embedded interpreter. It can be used to automate and customize Pro/ENGINEER, create Vendor Neutral Archive (VNA) format files and re-create CAD models from the VNA files. This has applications in sanitizing classified CAD models created in a classified environment for transfer to an open environment, creating template models for modification to finished models by non-expert users, and transfer of design intent data to other modeling technologies.

  12. Lightweight application for generating clinical research information systems: MAGIC.

    PubMed

    Leskošek, Brane; Pajntar, Marjan

    2015-12-01

    Our purpose was to build and test a lightweight solution for generating clinical research information systems (CRIS) that would allow non-IT professionals with basic knowledge of computer usage to quickly define and build a ready-to-use, safe and secure web-based clinical research system for data management. We use the acronym MAGIC (Medical Application Generator InteraCtive) for the system. The generated CRIS should be very easy to build and use, so a common LAMP (Linux Apache MySQL Perl) platform was used, which also enables short development cycles. The application was built and tested using eXtreme Programming (XP) principles by a small development team consisting of one informatics specialist, one physician and one graphical designer/programmer. The parameter and graphical user interface (GUI) definitions for the CRIS can be made by non-IT professionals using an intuitive English-language-like formalism called application definition language (ADL). From these definitions, the MAGIC builds an end-user CRIS that can be used on a wide variety of platforms (from standard workstations to hand-held devices). A working example of a national health-care-quality assessment program is presented to illustrate this process. The lightweight application for generating CRIS (MAGIC) has proven to be useful for both clinical and analytical users in real working environment. To achieve better performance and interoperability, we are planning to recompile the application using XML schemas (XSD) in HL7 CDA or openEHR archetypes formats used for parameters definition and for data interchange between different information systems.

  13. FastaValidator: an open-source Java library to parse and validate FASTA formatted sequences.

    PubMed

    Waldmann, Jost; Gerken, Jan; Hankeln, Wolfgang; Schweer, Timmy; Glöckner, Frank Oliver

    2014-06-14

    Advances in sequencing technologies challenge the efficient importing and validation of FASTA formatted sequence data which is still a prerequisite for most bioinformatic tools and pipelines. Comparative analysis of commonly used Bio*-frameworks (BioPerl, BioJava and Biopython) shows that their scalability and accuracy is hampered. FastaValidator represents a platform-independent, standardized, light-weight software library written in the Java programming language. It targets computer scientists and bioinformaticians writing software which needs to parse quickly and accurately large amounts of sequence data. For end-users FastaValidator includes an interactive out-of-the-box validation of FASTA formatted files, as well as a non-interactive mode designed for high-throughput validation in software pipelines. The accuracy and performance of the FastaValidator library qualifies it for large data sets such as those commonly produced by massive parallel (NGS) technologies. It offers scientists a fast, accurate and standardized method for parsing and validating FASTA formatted sequence data.

  14. Evolving Strategies for the Incorporation of Bioinformatics Within the Undergraduate Cell Biology Curriculum

    PubMed Central

    Honts, Jerry E.

    2003-01-01

    Recent advances in genomics and structural biology have resulted in an unprecedented increase in biological data available from Internet-accessible databases. In order to help students effectively use this vast repository of information, undergraduate biology students at Drake University were introduced to bioinformatics software and databases in three courses, beginning with an introductory course in cell biology. The exercises and projects that were used to help students develop literacy in bioinformatics are described. In a recently offered course in bioinformatics, students developed their own simple sequence analysis tool using the Perl programming language. These experiences are described from the point of view of the instructor as well as the students. A preliminary assessment has been made of the degree to which students had developed a working knowledge of bioinformatics concepts and methods. Finally, some conclusions have been drawn from these courses that may be helpful to instructors wishing to introduce bioinformatics within the undergraduate biology curriculum. PMID:14673489

  15. Myles A. Steiner | NREL

    Science.gov Websites

    ; Emmett E. Perl, John Simon, Daniel J. Friedman, Nikhil Jain, Paul Sharps, Claiborne McPheeters, Yukun Sun , Kevin L. Schulte, Ryan M. France, William E. McMahon, Emmett E. Perl, Daniel J. Friedman, Journal of ; E.E. Perl, D. Kuciauskas, J. Simon, D.J. Friedman, M.A. Steiner, Journal of Applied Physics, 122

  16. Reengineering Workflow for Curation of DICOM Datasets.

    PubMed

    Bennett, William; Smith, Kirk; Jarosz, Quasar; Nolan, Tracy; Bosch, Walter

    2018-06-15

    Reusable, publicly available data is a pillar of open science and rapid advancement of cancer imaging research. Sharing data from completed research studies not only saves research dollars required to collect data, but also helps insure that studies are both replicable and reproducible. The Cancer Imaging Archive (TCIA) is a global shared repository for imaging data related to cancer. Insuring the consistency, scientific utility, and anonymity of data stored in TCIA is of utmost importance. As the rate of submission to TCIA has been increasing, both in volume and complexity of DICOM objects stored, the process of curation of collections has become a bottleneck in acquisition of data. In order to increase the rate of curation of image sets, improve the quality of the curation, and better track the provenance of changes made to submitted DICOM image sets, a custom set of tools was developed, using novel methods for the analysis of DICOM data sets. These tools are written in the programming language perl, use the open-source database PostgreSQL, make use of the perl DICOM routines in the open-source package Posda, and incorporate DICOM diagnostic tools from other open-source packages, such as dicom3tools. These tools are referred to as the "Posda Tools." The Posda Tools are open source and available via git at https://github.com/UAMS-DBMI/PosdaTools . In this paper, we briefly describe the Posda Tools and discuss the novel methods employed by these tools to facilitate rapid analysis of DICOM data, including the following: (1) use a database schema which is more permissive, and differently normalized from traditional DICOM databases; (2) perform integrity checks automatically on a bulk basis; (3) apply revisions to DICOM datasets on an bulk basis, either through a web-based interface or via command line executable perl scripts; (4) all such edits are tracked in a revision tracker and may be rolled back; (5) a UI is provided to inspect the results of such edits, to verify that they are what was intended; (6) identification of DICOM Studies, Series, and SOP instances using "nicknames" which are persistent and have well-defined scope to make expression of reported DICOM errors easier to manage; and (7) rapidly identify potential duplicate DICOM datasets by pixel data is provided; this can be used, e.g., to identify submission subjects which may relate to the same individual, without identifying the individual.

  17. PDB explorer -- a web based algorithm for protein annotation viewer and 3D visualization.

    PubMed

    Nayarisseri, Anuraj; Shardiwal, Rakesh Kumar; Yadav, Mukesh; Kanungo, Neha; Singh, Pooja; Shah, Pratik; Ahmed, Sheaza

    2014-12-01

    The PDB file format, is a text format characterizing the three dimensional structures of macro molecules available in the Protein Data Bank (PDB). Determined protein structure are found in coalition with other molecules or ions such as nucleic acids, water, ions, Drug molecules and so on, which therefore can be described in the PDB format and have been deposited in PDB database. PDB is a machine generated file, it's not human readable format, to read this file we need any computational tool to understand it. The objective of our present study is to develop a free online software for retrieval, visualization and reading of annotation of a protein 3D structure which is available in PDB database. Main aim is to create PDB file in human readable format, i.e., the information in PDB file is converted in readable sentences. It displays all possible information from a PDB file including 3D structure of that file. Programming languages and scripting languages like Perl, CSS, Javascript, Ajax, and HTML have been used for the development of PDB Explorer. The PDB Explorer directly parses the PDB file, calling methods for parsed element secondary structure element, atoms, coordinates etc. PDB Explorer is freely available at http://www.pdbexplorer.eminentbio.com/home with no requirement of log-in.

  18. e-Stars Template Builder

    NASA Technical Reports Server (NTRS)

    Cox, Brian

    2003-01-01

    e-Stars Template Builder is a computer program that implements a concept of enabling users to rapidly gain access to information on projects of NASA's Jet Propulsion Laboratory. The information about a given project is not stored in a data base, but rather, in a network that follows the project as it develops. e-Stars Template Builder resides on a server computer, using Practical Extraction and Reporting Language (PERL) scripts to create what are called "e-STARS node templates," which are software constructs that allow for project-specific configurations. The software resides on the server and does not require specific software on the user machine except for an Internet browser. A user's computer need not be equipped with special software (other than an Internet-browser program). e-Stars Template Builder is compatible with Windows, Macintosh, and UNIX operating systems. A user invokes e-Stars Template Builder from a browser window. Operations that can be performed by the user include the creation of child processes and the addition of links and descriptions of documentation to existing pages or nodes. By means of this addition of "child processes" of nodes, a network that reflects the development of a project is generated.

  19. ICT: isotope correction toolbox.

    PubMed

    Jungreuthmayer, Christian; Neubauer, Stefan; Mairinger, Teresa; Zanghellini, Jürgen; Hann, Stephan

    2016-01-01

    Isotope tracer experiments are an invaluable technique to analyze and study the metabolism of biological systems. However, isotope labeling experiments are often affected by naturally abundant isotopes especially in cases where mass spectrometric methods make use of derivatization. The correction of these additive interferences--in particular for complex isotopic systems--is numerically challenging and still an emerging field of research. When positional information is generated via collision-induced dissociation, even more complex calculations for isotopic interference correction are necessary. So far, no freely available tools can handle tandem mass spectrometry data. We present isotope correction toolbox, a program that corrects tandem mass isotopomer data from tandem mass spectrometry experiments. Isotope correction toolbox is written in the multi-platform programming language Perl and, therefore, can be used on all commonly available computer platforms. Source code and documentation can be freely obtained under the Artistic License or the GNU General Public License from: https://github.com/jungreuc/isotope_correction_toolbox/ {christian.jungreuthmayer@boku.ac.at,juergen.zanghellini@boku.ac.at} Supplementary data are available at Bioinformatics online. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  20. Higher prices in Jamaica.

    PubMed

    1982-03-01

    Price increases in the Jamaica CSM program went into effect on August 31, 1981. The program began in 1975. While the need for higher prices has been under discussion for the past 3 years, this is the 1st time the requisite approval from the Jamaica Price Commission has been obtained. The Jamaica National Family Planning Board (JNFPB) reports that the Panther 3-pack (condom) is up US$0.15 to US$0.30. Each Perle package (oral contraceptive) was increased by US$0.20. Single cycle Perle now sells for US$0.50, and 3-pack Perle sells for US$1.10. The 6-year price stagnation experienced by the CSM program resulted in a decreasing operational budget as program costs continued to rise. Marketing costs alone during this period escalated by 100-300%. For example, Panther pop-up display cartons cost the project US 16U each in 1975. By 1979 the same product cost US 49U. Newspaper advertisements have increased from the 1975 cost of US$68.00 to nearly $200.00 per placement. The overall inflation rate in Jamaica during the last 5 years has averaged more than 20% annually. In the face of these rising costs, outlet expansion for Perle has been prevented, wholesaler margins have been unavailable, and new retailer training has been discontinued. It is projected that the new prices will result in an annual increased revenues of US$80,000 which will be used to reinstate these essential marketing activities. The JNFPB is also planning to introduce a Panther 12-pack and Panther strips to the CSM product line. According to Marketing Manager Aston Evans, "We believe the public is now ready for this type of packaging" which is scheduled to be available soon. Panther is presently only available in a 3-pack, but annual sales have been steady. The new 12-pack will be stocked on supermarket shelves to provide higher product visibility and wider distribution. The selling price has been set as US$1.20 and is expected to yield a 25% increase in sales during the 1st year. A complete sales promotion and advertising campaign will accompany the 12-pack introduction. The marketing plan for Panther strips emphasizes placement in government and private sector offices and factories throughout the country. In the deep rural areas the strips will be available for sale in shops, bars, nightclubs, and other distribution points. full text

  1. Perl One-Liners: Bridging the Gap Between Large Data Sets and Analysis Tools.

    PubMed

    Hokamp, Karsten

    2015-01-01

    Computational analyses of biological data are becoming increasingly powerful, and researchers intending on carrying out their own analyses can often choose from a wide array of tools and resources. However, their application might be obstructed by the wide variety of different data formats that are in use, from standard, commonly used formats to output files from high-throughput analysis platforms. The latter are often too large to be opened, viewed, or edited by standard programs, potentially leading to a bottleneck in the analysis. Perl one-liners provide a simple solution to quickly reformat, filter, and merge data sets in preparation for downstream analyses. This chapter presents example code that can be easily adjusted to meet individual requirements. An online version is available at http://bioinf.gen.tcd.ie/pol.

  2. Thermoreception and Nociception of the Skin: A Classic Paper of Bessou and Perl and Analyses of Thermal Sensitivity during a Student Laboratory Exercise

    ERIC Educational Resources Information Center

    Kuhtz-Buschbeck, Johann P.; Andresen, Wiebke; Gobel, Stephan; Gilster, Rene; Stick, Carsten

    2010-01-01

    About four decades ago, Perl and collaborators were the first ones who unambiguously identified specifically nociceptive neurons in the periphery. In their classic work, they recorded action potentials from single C-fibers of a cutaneous nerve in cats while applying carefully graded stimuli to the skin (Bessou P, Perl ER. Response of cutaneous…

  3. Analytic reconstruction of magnetic resonance imaging signal obtained from a periodic encoding field.

    PubMed

    Rybicki, F J; Hrovat, M I; Patz, S

    2000-09-01

    We have proposed a two-dimensional PERiodic-Linear (PERL) magnetic encoding field geometry B(x,y) = g(y)y cos(q(x)x) and a magnetic resonance imaging pulse sequence which incorporates two fields to image a two-dimensional spin density: a standard linear gradient in the x dimension, and the PERL field. Because of its periodicity, the PERL field produces a signal where the phase of the two dimensions is functionally different. The x dimension is encoded linearly, but the y dimension appears as the argument of a sinusoidal phase term. Thus, the time-domain signal and image spin density are not related by a two-dimensional Fourier transform. They are related by a one-dimensional Fourier transform in the x dimension and a new Bessel function integral transform (the PERL transform) in the y dimension. The inverse of the PERL transform provides a reconstruction algorithm for the y dimension of the spin density from the signal space. To date, the inverse transform has been computed numerically by a Bessel function expansion over its basis functions. This numerical solution used a finite sum to approximate an infinite summation and thus introduced a truncation error. This work analytically determines the basis functions for the PERL transform and incorporates them into the reconstruction algorithm. The improved algorithm is demonstrated by (1) direct comparison between the numerically and analytically computed basis functions, and (2) reconstruction of a known spin density. The new solution for the basis functions also lends proof of the system function for the PERL transform under specific conditions.

  4. Simple proteomics data analysis in the object-oriented PowerShell.

    PubMed

    Mohammed, Yassene; Palmblad, Magnus

    2013-01-01

    Scripting languages such as Perl and Python are appreciated for solving simple, everyday tasks in bioinformatics. A more recent, object-oriented command shell and scripting language, Windows PowerShell, has many attractive features: an object-oriented interactive command line, fluent navigation and manipulation of XML files, ability to consume Web services from the command line, consistent syntax and grammar, rich regular expressions, and advanced output formatting. The key difference between classical command shells and scripting languages, such as bash, and object-oriented ones, such as PowerShell, is that in the latter the result of a command is a structured object with inherited properties and methods rather than a simple stream of characters. Conveniently, PowerShell is included in all new releases of Microsoft Windows and therefore already installed on most computers in classrooms and teaching labs. In this chapter we demonstrate how PowerShell in particular allows easy interaction with mass spectrometry data in XML formats, connection to Web services for tools such as BLAST, and presentation of results as formatted text or graphics. These features make PowerShell much more than "yet another scripting language."

  5. Lightweight computational steering of very large scale molecular dynamics simulations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Beazley, D.M.; Lomdahl, P.S.

    1996-09-01

    We present a computational steering approach for controlling, analyzing, and visualizing very large scale molecular dynamics simulations involving tens to hundreds of millions of atoms. Our approach relies on extensible scripting languages and an easy to use tool for building extensions and modules. The system is extremely easy to modify, works with existing C code, is memory efficient, and can be used from inexpensive workstations and networks. We demonstrate how we have used this system to manipulate data from production MD simulations involving as many as 104 million atoms running on the CM-5 and Cray T3D. We also show howmore » this approach can be used to build systems that integrate common scripting languages (including Tcl/Tk, Perl, and Python), simulation code, user extensions, and commercial data analysis packages.« less

  6. BIO::Phylo-phyloinformatic analysis using perl.

    PubMed

    Vos, Rutger A; Caravas, Jason; Hartmann, Klaas; Jensen, Mark A; Miller, Chase

    2011-02-27

    Phyloinformatic analyses involve large amounts of data and metadata of complex structure. Collecting, processing, analyzing, visualizing and summarizing these data and metadata should be done in steps that can be automated and reproduced. This requires flexible, modular toolkits that can represent, manipulate and persist phylogenetic data and metadata as objects with programmable interfaces. This paper presents Bio::Phylo, a Perl5 toolkit for phyloinformatic analysis. It implements classes and methods that are compatible with the well-known BioPerl toolkit, but is independent from it (making it easy to install) and features a richer API and a data model that is better able to manage the complex relationships between different fundamental data and metadata objects in phylogenetics. It supports commonly used file formats for phylogenetic data including the novel NeXML standard, which allows rich annotations of phylogenetic data to be stored and shared. Bio::Phylo can interact with BioPerl, thereby giving access to the file formats that BioPerl supports. Many methods for data simulation, transformation and manipulation, the analysis of tree shape, and tree visualization are provided. Bio::Phylo is composed of 59 richly documented Perl5 modules. It has been deployed successfully on a variety of computer architectures (including various Linux distributions, Mac OS X versions, Windows, Cygwin and UNIX-like systems). It is available as open source (GPL) software from http://search.cpan.org/dist/Bio-Phylo.

  7. BIO::Phylo-phyloinformatic analysis using perl

    PubMed Central

    2011-01-01

    Background Phyloinformatic analyses involve large amounts of data and metadata of complex structure. Collecting, processing, analyzing, visualizing and summarizing these data and metadata should be done in steps that can be automated and reproduced. This requires flexible, modular toolkits that can represent, manipulate and persist phylogenetic data and metadata as objects with programmable interfaces. Results This paper presents Bio::Phylo, a Perl5 toolkit for phyloinformatic analysis. It implements classes and methods that are compatible with the well-known BioPerl toolkit, but is independent from it (making it easy to install) and features a richer API and a data model that is better able to manage the complex relationships between different fundamental data and metadata objects in phylogenetics. It supports commonly used file formats for phylogenetic data including the novel NeXML standard, which allows rich annotations of phylogenetic data to be stored and shared. Bio::Phylo can interact with BioPerl, thereby giving access to the file formats that BioPerl supports. Many methods for data simulation, transformation and manipulation, the analysis of tree shape, and tree visualization are provided. Conclusions Bio::Phylo is composed of 59 richly documented Perl5 modules. It has been deployed successfully on a variety of computer architectures (including various Linux distributions, Mac OS X versions, Windows, Cygwin and UNIX-like systems). It is available as open source (GPL) software from http://search.cpan.org/dist/Bio-Phylo PMID:21352572

  8. LCG MCDB—a knowledgebase of Monte-Carlo simulated events

    NASA Astrophysics Data System (ADS)

    Belov, S.; Dudko, L.; Galkin, E.; Gusev, A.; Pokorski, W.; Sherstnev, A.

    2008-02-01

    In this paper we report on LCG Monte-Carlo Data Base (MCDB) and software which has been developed to operate MCDB. The main purpose of the LCG MCDB project is to provide a storage and documentation system for sophisticated event samples simulated for the LHC Collaborations by experts. In many cases, the modern Monte-Carlo simulation of physical processes requires expert knowledge in Monte-Carlo generators or significant amount of CPU time to produce the events. MCDB is a knowledgebase mainly dedicated to accumulate simulated events of this type. The main motivation behind LCG MCDB is to make the sophisticated MC event samples available for various physical groups. All the data from MCDB is accessible in several convenient ways. LCG MCDB is being developed within the CERN LCG Application Area Simulation project. Program summaryProgram title: LCG Monte-Carlo Data Base Catalogue identifier: ADZX_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/ADZX_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: GNU General Public Licence No. of lines in distributed program, including test data, etc.: 30 129 No. of bytes in distributed program, including test data, etc.: 216 943 Distribution format: tar.gz Programming language: Perl Computer: CPU: Intel Pentium 4, RAM: 1 Gb, HDD: 100 Gb Operating system: Scientific Linux CERN 3/4 RAM: 1 073 741 824 bytes (1 Gb) Classification: 9 External routines:perl >= 5.8.5; Perl modules DBD-mysql >= 2.9004, File::Basename, GD::SecurityImage, GD::SecurityImage::AC, Linux::Statistics, XML::LibXML > 1.6, XML::SAX, XML::NamespaceSupport; Apache HTTP Server >= 2.0.59; mod auth external >= 2.2.9; edg-utils-system RPM package; gd >= 2.0.28; rpm package CASTOR-client >= 2.1.2-4; arc-server (optional) Nature of problem: Often, different groups of experimentalists prepare similar samples of particle collision events or turn to the same group of authors of Monte-Carlo (MC) generators to prepare the events. For example, the same MC samples of Standard Model (SM) processes can be employed for the investigations either in the SM analyses (as a signal) or in searches for new phenomena in Beyond Standard Model analyses (as a background). If the samples are made available publicly and equipped with corresponding and comprehensive documentation, it can speed up cross checks of the samples themselves and physical models applied. Some event samples require a lot of computing resources for preparation. So, a central storage of the samples prevents possible waste of researcher time and computing resources, which can be used to prepare the same events many times. Solution method: Creation of a special knowledgebase (MCDB) designed to keep event samples for the LHC experimental and phenomenological community. The knowledgebase is realized as a separate web-server ( http://mcdb.cern.ch). All event samples are kept on types at CERN. Documentation describing the events is the main contents of MCDB. Users can browse the knowledgebase, read and comment articles (documentation), and download event samples. Authors can upload new event samples, create new articles, and edit own articles. Restrictions: The software is adopted to solve the problems, described in the article and there are no any additional restrictions. Unusual features: The software provides a framework to store and document large files with flexible authentication and authorization system. Different external storages with large capacity can be used to keep the files. The WEB Content Management System provides all of the necessary interfaces for the authors of the files, end-users and administrators. Running time: Real time operations. References: [1] The main LCG MCDB server, http://mcdb.cern.ch/. [2] P. Bartalini, L. Dudko, A. Kryukov, I.V. Selyuzhenkov, A. Sherstnev, A. Vologdin, LCG Monte-Carlo data base, hep-ph/0404241. [3] J.P. Baud, B. Couturier, C. Curran, J.D. Durand, E. Knezo, S. Occhetti, O. Barring, CASTOR: status and evolution, cs.oh/0305047.

  9. Forensic Analysis of Compromised Computers

    NASA Technical Reports Server (NTRS)

    Wolfe, Thomas

    2004-01-01

    Directory Tree Analysis File Generator is a Practical Extraction and Reporting Language (PERL) script that simplifies and automates the collection of information for forensic analysis of compromised computer systems. During such an analysis, it is sometimes necessary to collect and analyze information about files on a specific directory tree. Directory Tree Analysis File Generator collects information of this type (except information about directories) and writes it to a text file. In particular, the script asks the user for the root of the directory tree to be processed, the name of the output file, and the number of subtree levels to process. The script then processes the directory tree and puts out the aforementioned text file. The format of the text file is designed to enable the submission of the file as input to a spreadsheet program, wherein the forensic analysis is performed. The analysis usually consists of sorting files and examination of such characteristics of files as ownership, time of creation, and time of most recent access, all of which characteristics are among the data included in the text file.

  10. NeisseriaBase: a specialised Neisseria genomic resource and analysis platform.

    PubMed

    Zheng, Wenning; Mutha, Naresh V R; Heydari, Hamed; Dutta, Avirup; Siow, Cheuk Chuen; Jakubovics, Nicholas S; Wee, Wei Yee; Tan, Shi Yang; Ang, Mia Yang; Wong, Guat Jah; Choo, Siew Woh

    2016-01-01

    Background. The gram-negative Neisseria is associated with two of the most potent human epidemic diseases: meningococcal meningitis and gonorrhoea. In both cases, disease is caused by bacteria colonizing human mucosal membrane surfaces. Overall, the genus shows great diversity and genetic variation mainly due to its ability to acquire and incorporate genetic material from a diverse range of sources through horizontal gene transfer. Although a number of databases exist for the Neisseria genomes, they are mostly focused on the pathogenic species. In this present study we present the freely available NeisseriaBase, a database dedicated to the genus Neisseria encompassing the complete and draft genomes of 15 pathogenic and commensal Neisseria species. Methods. The genomic data were retrieved from National Center for Biotechnology Information (NCBI) and annotated using the RAST server which were then stored into the MySQL database. The protein-coding genes were further analyzed to obtain information such as calculation of GC content (%), predicted hydrophobicity and molecular weight (Da) using in-house Perl scripts. The web application was developed following the secure four-tier web application architecture: (1) client workstation, (2) web server, (3) application server, and (4) database server. The web interface was constructed using PHP, JavaScript, jQuery, AJAX and CSS, utilizing the model-view-controller (MVC) framework. The in-house developed bioinformatics tools implemented in NeisseraBase were developed using Python, Perl, BioPerl and R languages. Results. Currently, NeisseriaBase houses 603,500 Coding Sequences (CDSs), 16,071 RNAs and 13,119 tRNA genes from 227 Neisseria genomes. The database is equipped with interactive web interfaces. Incorporation of the JBrowse genome browser in the database enables fast and smooth browsing of Neisseria genomes. NeisseriaBase includes the standard BLAST program to facilitate homology searching, and for Virulence Factor Database (VFDB) specific homology searches, the VFDB BLAST is also incorporated into the database. In addition, NeisseriaBase is equipped with in-house designed tools such as the Pairwise Genome Comparison tool (PGC) for comparative genomic analysis and the Pathogenomics Profiling Tool (PathoProT) for the comparative pathogenomics analysis of Neisseria strains. Discussion. This user-friendly database not only provides access to a host of genomic resources on Neisseria but also enables high-quality comparative genome analysis, which is crucial for the expanding scientific community interested in Neisseria research. This database is freely available at http://neisseria.um.edu.my.

  11. NeisseriaBase: a specialised Neisseria genomic resource and analysis platform

    PubMed Central

    Zheng, Wenning; Mutha, Naresh V.R.; Heydari, Hamed; Dutta, Avirup; Siow, Cheuk Chuen; Jakubovics, Nicholas S.; Wee, Wei Yee; Tan, Shi Yang; Ang, Mia Yang; Wong, Guat Jah

    2016-01-01

    Background. The gram-negative Neisseria is associated with two of the most potent human epidemic diseases: meningococcal meningitis and gonorrhoea. In both cases, disease is caused by bacteria colonizing human mucosal membrane surfaces. Overall, the genus shows great diversity and genetic variation mainly due to its ability to acquire and incorporate genetic material from a diverse range of sources through horizontal gene transfer. Although a number of databases exist for the Neisseria genomes, they are mostly focused on the pathogenic species. In this present study we present the freely available NeisseriaBase, a database dedicated to the genus Neisseria encompassing the complete and draft genomes of 15 pathogenic and commensal Neisseria species. Methods. The genomic data were retrieved from National Center for Biotechnology Information (NCBI) and annotated using the RAST server which were then stored into the MySQL database. The protein-coding genes were further analyzed to obtain information such as calculation of GC content (%), predicted hydrophobicity and molecular weight (Da) using in-house Perl scripts. The web application was developed following the secure four-tier web application architecture: (1) client workstation, (2) web server, (3) application server, and (4) database server. The web interface was constructed using PHP, JavaScript, jQuery, AJAX and CSS, utilizing the model-view-controller (MVC) framework. The in-house developed bioinformatics tools implemented in NeisseraBase were developed using Python, Perl, BioPerl and R languages. Results. Currently, NeisseriaBase houses 603,500 Coding Sequences (CDSs), 16,071 RNAs and 13,119 tRNA genes from 227 Neisseria genomes. The database is equipped with interactive web interfaces. Incorporation of the JBrowse genome browser in the database enables fast and smooth browsing of Neisseria genomes. NeisseriaBase includes the standard BLAST program to facilitate homology searching, and for Virulence Factor Database (VFDB) specific homology searches, the VFDB BLAST is also incorporated into the database. In addition, NeisseriaBase is equipped with in-house designed tools such as the Pairwise Genome Comparison tool (PGC) for comparative genomic analysis and the Pathogenomics Profiling Tool (PathoProT) for the comparative pathogenomics analysis of Neisseria strains. Discussion. This user-friendly database not only provides access to a host of genomic resources on Neisseria but also enables high-quality comparative genome analysis, which is crucial for the expanding scientific community interested in Neisseria research. This database is freely available at http://neisseria.um.edu.my. PMID:27017950

  12. BEAM DYNAMICS SIMULATIONS FOR A DC GUN BASED INJECTOR FOR PERL.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    ZHOU,F.; BEN-ZVI,I.; WANG,X.J.

    2001-06-18

    The National Synchrotron Light Source (NSLS) at Brookhaven National Laboratory (BNL) is considering an upgrade based on the Photoinjected Energy Recovering Linac (PERL). The various injector schemes for this machine are being extensively investigated at BNL. One of the possible options is photocathode DC gun. The schematic layout of a PERL DC gun based injector and its preliminary beam dynamics are presented in this paper. The transverse and longitudinal emittance of photo-electron beam were optimized for a DC field 500 kV.

  13. The Proteins API: accessing key integrated protein and genome information

    PubMed Central

    Antunes, Ricardo; Alpi, Emanuele; Gonzales, Leonardo; Liu, Wudong; Luo, Jie; Qi, Guoying; Turner, Edd

    2017-01-01

    Abstract The Proteins API provides searching and programmatic access to protein and associated genomics data such as curated protein sequence positional annotations from UniProtKB, as well as mapped variation and proteomics data from large scale data sources (LSS). Using the coordinates service, researchers are able to retrieve the genomic sequence coordinates for proteins in UniProtKB. This, the LSS genomics and proteomics data for UniProt proteins is programmatically only available through this service. A Swagger UI has been implemented to provide documentation, an interface for users, with little or no programming experience, to ‘talk’ to the services to quickly and easily formulate queries with the services and obtain dynamically generated source code for popular programming languages, such as Java, Perl, Python and Ruby. Search results are returned as standard JSON, XML or GFF data objects. The Proteins API is a scalable, reliable, fast, easy to use RESTful services that provides a broad protein information resource for users to ask questions based upon their field of expertise and allowing them to gain an integrated overview of protein annotations available to aid their knowledge gain on proteins in biological processes. The Proteins API is available at (http://www.ebi.ac.uk/proteins/api/doc). PMID:28383659

  14. The Proteins API: accessing key integrated protein and genome information.

    PubMed

    Nightingale, Andrew; Antunes, Ricardo; Alpi, Emanuele; Bursteinas, Borisas; Gonzales, Leonardo; Liu, Wudong; Luo, Jie; Qi, Guoying; Turner, Edd; Martin, Maria

    2017-07-03

    The Proteins API provides searching and programmatic access to protein and associated genomics data such as curated protein sequence positional annotations from UniProtKB, as well as mapped variation and proteomics data from large scale data sources (LSS). Using the coordinates service, researchers are able to retrieve the genomic sequence coordinates for proteins in UniProtKB. This, the LSS genomics and proteomics data for UniProt proteins is programmatically only available through this service. A Swagger UI has been implemented to provide documentation, an interface for users, with little or no programming experience, to 'talk' to the services to quickly and easily formulate queries with the services and obtain dynamically generated source code for popular programming languages, such as Java, Perl, Python and Ruby. Search results are returned as standard JSON, XML or GFF data objects. The Proteins API is a scalable, reliable, fast, easy to use RESTful services that provides a broad protein information resource for users to ask questions based upon their field of expertise and allowing them to gain an integrated overview of protein annotations available to aid their knowledge gain on proteins in biological processes. The Proteins API is available at (http://www.ebi.ac.uk/proteins/api/doc). © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  15. Quality assessment of protein model-structures using evolutionary conservation.

    PubMed

    Kalman, Matan; Ben-Tal, Nir

    2010-05-15

    Programs that evaluate the quality of a protein structural model are important both for validating the structure determination procedure and for guiding the model-building process. Such programs are based on properties of native structures that are generally not expected for faulty models. One such property, which is rarely used for automatic structure quality assessment, is the tendency for conserved residues to be located at the structural core and for variable residues to be located at the surface. We present ConQuass, a novel quality assessment program based on the consistency between the model structure and the protein's conservation pattern. We show that it can identify problematic structural models, and that the scores it assigns to the server models in CASP8 correlate with the similarity of the models to the native structure. We also show that when the conservation information is reliable, the method's performance is comparable and complementary to that of the other single-structure quality assessment methods that participated in CASP8 and that do not use additional structural information from homologs. A perl implementation of the method, as well as the various perl and R scripts used for the analysis are available at http://bental.tau.ac.il/ConQuass/. nirb@tauex.tau.ac.il Supplementary data are available at Bioinformatics online.

  16. Martin Perl and the Tau Lepton

    Science.gov Websites

    ; Technology in Experimental Particle Physics", Winter 1995, Vol. 25, No. 4, pages 4 - 27 Perl compares you to non-federal websites. Their policies may differ from this site. Website Policies/Important

  17. Wrapping up BLAST and other applications for use on Unix clusters.

    PubMed

    Hokamp, Karsten; Shields, Denis C; Wolfe, Kenneth H; Caffrey, Daniel R

    2003-02-12

    We have developed two programs that speed up common bioinformatic applications by spreading them across a UNIX cluster.(1) BLAST.pm, a new module for the 'MOLLUSC' package. (2) WRAPID, a simple tool for parallelizing large numbers of small instances of programs such as BLAST, FASTA and CLUSTALW. The packages were developed in Perl on a 20-node Linux cluster and are provided together with a configuration script and documentation. They can be freely downloaded from http://wolfe.gen.tcd.ie/wrapper.

  18. Perl Extension to the Bproc Library

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Grunau, Daryl W.

    2004-06-07

    The Beowulf Distributed process Space (Bproc) software stack is comprised of UNIX/Linux kernel modifications and a support library by which a cluster of machines, each running their own private kernel, can present itself as a unified process space to the user. A Bproc cluster contains a single front-end machine and many back-end nodes which receive and run processes given to them by the front-end. Any process which is migrated to a back-end node is also visible as a ghost process on the fron-end, and may be controlled there using traditional UNIX semantics (e.g. ps(1), kill(1), etc). This software is amore » Perl extension to the Bproc library which enables the Perl programmer to make direct calls to functions within the Bproc library. See http://www.clustermatic.org, http://bproc.sourceforge.net, and http://www.perl.org« less

  19. Logs Perl Module

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Owen, R. K.

    2007-04-04

    A perl module designed to read and parse the voluminous set of event or accounting log files produced by a Portable Batch System (PBS) server. This module can filter on date-time and/or record type. The data can be returned in a variety of formats.

  20. Discovery of replicating circular RNAs by RNA-seq and computational algorithms.

    PubMed

    Zhang, Zhixiang; Qi, Shuishui; Tang, Nan; Zhang, Xinxin; Chen, Shanshan; Zhu, Pengfei; Ma, Lin; Cheng, Jinping; Xu, Yun; Lu, Meiguang; Wang, Hongqing; Ding, Shou-Wei; Li, Shifang; Wu, Qingfa

    2014-12-01

    Replicating circular RNAs are independent plant pathogens known as viroids, or act to modulate the pathogenesis of plant and animal viruses as their satellite RNAs. The rate of discovery of these subviral pathogens was low over the past 40 years because the classical approaches are technical demanding and time-consuming. We previously described an approach for homology-independent discovery of replicating circular RNAs by analysing the total small RNA populations from samples of diseased tissues with a computational program known as progressive filtering of overlapping small RNAs (PFOR). However, PFOR written in PERL language is extremely slow and is unable to discover those subviral pathogens that do not trigger in vivo accumulation of extensively overlapping small RNAs. Moreover, PFOR is yet to identify a new viroid capable of initiating independent infection. Here we report the development of PFOR2 that adopted parallel programming in the C++ language and was 3 to 8 times faster than PFOR. A new computational program was further developed and incorporated into PFOR2 to allow the identification of circular RNAs by deep sequencing of long RNAs instead of small RNAs. PFOR2 analysis of the small RNA libraries from grapevine and apple plants led to the discovery of Grapevine latent viroid (GLVd) and Apple hammerhead viroid-like RNA (AHVd-like RNA), respectively. GLVd was proposed as a new species in the genus Apscaviroid, because it contained the typical structural elements found in this group of viroids and initiated independent infection in grapevine seedlings. AHVd-like RNA encoded a biologically active hammerhead ribozyme in both polarities, and was not specifically associated with any of the viruses found in apple plants. We propose that these computational algorithms have the potential to discover novel circular RNAs in plants, invertebrates and vertebrates regardless of whether they replicate and/or induce the in vivo accumulation of small RNAs.

  1. Discovery of Replicating Circular RNAs by RNA-Seq and Computational Algorithms

    PubMed Central

    Tang, Nan; Zhang, Xinxin; Chen, Shanshan; Zhu, Pengfei; Ma, Lin; Cheng, Jinping; Xu, Yun; Lu, Meiguang; Wang, Hongqing; Ding, Shou-Wei; Li, Shifang; Wu, Qingfa

    2014-01-01

    Replicating circular RNAs are independent plant pathogens known as viroids, or act to modulate the pathogenesis of plant and animal viruses as their satellite RNAs. The rate of discovery of these subviral pathogens was low over the past 40 years because the classical approaches are technical demanding and time-consuming. We previously described an approach for homology-independent discovery of replicating circular RNAs by analysing the total small RNA populations from samples of diseased tissues with a computational program known as progressive filtering of overlapping small RNAs (PFOR). However, PFOR written in PERL language is extremely slow and is unable to discover those subviral pathogens that do not trigger in vivo accumulation of extensively overlapping small RNAs. Moreover, PFOR is yet to identify a new viroid capable of initiating independent infection. Here we report the development of PFOR2 that adopted parallel programming in the C++ language and was 3 to 8 times faster than PFOR. A new computational program was further developed and incorporated into PFOR2 to allow the identification of circular RNAs by deep sequencing of long RNAs instead of small RNAs. PFOR2 analysis of the small RNA libraries from grapevine and apple plants led to the discovery of Grapevine latent viroid (GLVd) and Apple hammerhead viroid-like RNA (AHVd-like RNA), respectively. GLVd was proposed as a new species in the genus Apscaviroid, because it contained the typical structural elements found in this group of viroids and initiated independent infection in grapevine seedlings. AHVd-like RNA encoded a biologically active hammerhead ribozyme in both polarities, and was not specifically associated with any of the viruses found in apple plants. We propose that these computational algorithms have the potential to discover novel circular RNAs in plants, invertebrates and vertebrates regardless of whether they replicate and/or induce the in vivo accumulation of small RNAs. PMID:25503469

  2. TRAP: automated classification, quantification and annotation of tandemly repeated sequences.

    PubMed

    Sobreira, Tiago José P; Durham, Alan M; Gruber, Arthur

    2006-02-01

    TRAP, the Tandem Repeats Analysis Program, is a Perl program that provides a unified set of analyses for the selection, classification, quantification and automated annotation of tandemly repeated sequences. TRAP uses the results of the Tandem Repeats Finder program to perform a global analysis of the satellite content of DNA sequences, permitting researchers to easily assess the tandem repeat content for both individual sequences and whole genomes. The results can be generated in convenient formats such as HTML and comma-separated values. TRAP can also be used to automatically generate annotation data in the format of feature table and GFF files.

  3. A Taxonomic Approach to the Gestalt Theory of Perls

    ERIC Educational Resources Information Center

    Raming, Henry E.; Frey, David H.

    1974-01-01

    This study applied content analysis and cluster analysis to the ideas of Fritz Perls to develop a taxonomy of Gestalt processes and goals. Summaries of the typal groups or clusters were written and the implications of taxonomic research in counseling discussed. (Author)

  4. Values in Fritz Perls's Gestalt Therapy: On the Dangers of Half-Truths.

    ERIC Educational Resources Information Center

    Cadwallader, Eva H.

    1984-01-01

    Examines some of the values in Perls's theory of psychotherapy, which his Gestalt Prayer epitomizes. Argues that at least five of the major value claims presupposed by his psychotherapeutic theory and practice are in fact dangerous half-truths. (JAC)

  5. Exceptional collections in surface-like categories

    NASA Astrophysics Data System (ADS)

    Kuznetsov, A. G.

    2017-09-01

    We provide a categorical framework for recent results of Markus Perling's on the combinatorics of exceptional collections on numerically rational surfaces. Using it we simplify and generalize some of Perling's results as well as Vial's criterion for the existence of a numerical exceptional collection. Bibliography: 18 titles.

  6. The Perls Perversion

    ERIC Educational Resources Information Center

    Morris, Kenneth T.

    1975-01-01

    Author describes the Perls perversion, the ego-centered attitude that people should live up to one's expectations and satisfy one's whims, which causes interpersonal friction. RET helps people counteract this perversion by sensitizing them to their internalized irrational belief system, disputing it, and trying to behave rationally. Commentary by…

  7. Reflections on Fritz Perls's Gestalt Prayer.

    ERIC Educational Resources Information Center

    Dolliver, Robert H.

    1981-01-01

    Reviews the alternative forms of Fritz Perls' Gestalt Prayer, which was highly influential in the 1970s when individuality and personal rights were being explored. The prayer is subject to interpretation. Counselors should clarify for clients that ongoing relationships require a great deal of work. (JAC)

  8. BpWrapper: BioPerl-based sequence and tree utilities for rapid prototyping of bioinformatics pipelines.

    PubMed

    Hernández, Yözen; Bernstein, Rocky; Pagan, Pedro; Vargas, Levy; McCaig, William; Ramrattan, Girish; Akther, Saymon; Larracuente, Amanda; Di, Lia; Vieira, Filipe G; Qiu, Wei-Gang

    2018-03-02

    Automated bioinformatics workflows are more robust, easier to maintain, and results more reproducible when built with command-line utilities than with custom-coded scripts. Command-line utilities further benefit by relieving bioinformatics developers to learn the use of, or to interact directly with, biological software libraries. There is however a lack of command-line utilities that leverage popular Open Source biological software toolkits such as BioPerl ( http://bioperl.org ) to make many of the well-designed, robust, and routinely used biological classes available for a wider base of end users. Designed as standard utilities for UNIX-family operating systems, BpWrapper makes functionality of some of the most popular BioPerl modules readily accessible on the command line to novice as well as to experienced bioinformatics practitioners. The initial release of BpWrapper includes four utilities with concise command-line user interfaces, bioseq, bioaln, biotree, and biopop, specialized for manipulation of molecular sequences, sequence alignments, phylogenetic trees, and DNA polymorphisms, respectively. Over a hundred methods are currently available as command-line options and new methods are easily incorporated. Performance of BpWrapper utilities lags that of precompiled utilities while equivalent to that of other utilities based on BioPerl. BpWrapper has been tested on BioPerl Release 1.6, Perl versions 5.10.1 to 5.25.10, and operating systems including Apple macOS, Microsoft Windows, and GNU/Linux. Release code is available from the Comprehensive Perl Archive Network (CPAN) at https://metacpan.org/pod/Bio::BPWrapper . Source code is available on GitHub at https://github.com/bioperl/p5-bpwrapper . BpWrapper improves on existing sequence utilities by following the design principles of Unix text utilities such including a concise user interface, extensive command-line options, and standard input/output for serialized operations. Further, dozens of novel methods for manipulation of sequences, alignments, and phylogenetic trees, unavailable in existing utilities (e.g., EMBOSS, Newick Utilities, and FAST), are provided. Bioinformaticians should find BpWrapper useful for rapid prototyping of workflows on the command-line without creating custom scripts for comparative genomics and other bioinformatics applications.

  9. Finding, Browsing and Getting Data Easily Using SPDF Web Services

    NASA Technical Reports Server (NTRS)

    Candey, R.; Chimiak, R.; Harris, B.; Johnson, R.; Kovalick, T.; Lal, N.; Leckner, H.; Liu, M.; McGuire, R.; Papitashvili, N.; hide

    2010-01-01

    The NASA GSFC Space Physics Data Facility (5PDF) provides heliophysics science-enabling information services for enhancing scientific research and enabling integration of these services into the Heliophysics Data Environment paradigm, via standards-based approach (SOAP) and Representational State Transfer (REST) web services in addition to web browser, FTP, and OPeNDAP interfaces. We describe these interfaces and the philosophies behind these web services, and show how to call them from various languages, such as IDL and Perl. We are working towards a "one simple line to call" philosophy extolled in the recent VxO discussions. Combining data from many instruments and missions enables broad research analysis and correlation and coordination with other experiments and missions.

  10. Charming Users into Scripting CIAO with Python

    NASA Astrophysics Data System (ADS)

    Burke, D. J.

    2011-07-01

    The Science Data Systems group of the Chandra X-ray Center provides a number of scripts and Python modules that extend the capabilities of CIAO. Experience in converting the existing scripts—written in a variety of languages such as bash, csh/tcsh, Perl and S-Lang—to Python, and conversations with users, led to the development of the ciao_contrib.runtool module. This allows users to easily run CIAO tools from Python scripts, and utilizes the metadata provided by the parameter-file system to create an API that provides the flexibility and safety guarantees of the command-line. The module is provided to the user community and is being used within our group to create new scripts.

  11. PRay - A graphical user interface for interactive visualization and modification of rayinvr models

    NASA Astrophysics Data System (ADS)

    Fromm, T.

    2016-01-01

    PRay is a graphical user interface for interactive displaying and editing of velocity models for seismic refraction. It is optimized for editing rayinvr models but can also be used as a dynamic viewer for ray tracing results from other software. The main features are the graphical editing of nodes and fast adjusting of the display (stations and phases). It can be extended by user-defined shell scripts and links to phase picking software. PRay is open source software written in the scripting language Perl, runs on Unix-like operating systems including Mac OS X and provides a version controlled source code repository for community development (https://sourceforge.net/projects/pray-plot-rayinvr/).

  12. The Cascading Impacts of Technology Selection: Incorporating Ruby on Rails into ECHO

    NASA Astrophysics Data System (ADS)

    Pilone, D.; Cechini, M.

    2010-12-01

    NASA’s Earth Observing System (EOS) ClearingHOuse (ECHO) is a SOA based Earth Science Data search and order system implemented in Java with one significant exception: the web client used by 98% of our users is written in Perl. After several decades of maintenance the Perl based application had reached the end of its serviceable life and ECHO was tasked with implementing a replacement. Despite a broad investment in Java, the ECHO team conducted a survey of modern development technologies including Flex, Python/Django, JSF2/Spring and Ruby on Rails. The team ultimately chose Ruby on Rails (RoR) with Cucumber for testing due to its perceived applicability to web application development and corresponding development efficiency gains. Both positive and negative impacts on the entire ECHO team, including our stakeholders, were immediate and sometimes subtle. The technology selection caused shifts in our architecture and design, development and deployment procedures, requirement definition approach, testing approach, and, somewhat surprisingly, our project team structure and software process. This presentation discusses our experiences, including technical, process, and psychological, using RoR on a production system. During this session we will discuss: - Real impacts of introducing a dynamic language to a Java team - Real and perceived efficiency advantages - Impediments to adoption and effectiveness - Impacts of transition from Test Driven Development to Behavior Driven Development - Leveraging Cucumber to provide fully executable requirement documents - Impacts on team structure and roles

  13. UPIC: Perl scripts to determine the number of SSR markers to run

    USDA-ARS?s Scientific Manuscript database

    We have developed Perl Scripts for the cost-effective planning of fingerprinting and genotyping experiments. The UPIC scripts detect the best combination of polymorphic simple sequence repeat (SSR) markers and provide coefficients of the amount of information obtainable (number of alleles of patter...

  14. Counselors' Evaluation of Rogers-Perls-Ellis's Relationship Skills

    ERIC Educational Resources Information Center

    Woodward, Wallace S.; And Others

    1975-01-01

    Participants (12 employment counselors and 10 counselor supervisors) attending a three-week workshop on enhancing relationship skills, evaluated the Rogers, Perls, Ellis film, Three Approaches to Psychotherapy, on 15 skills. Results indicate there was general agreement between the counselors and the supervisors when judging levels of therapist…

  15. KAnalyze: a fast versatile pipelined K-mer toolkit

    PubMed Central

    Audano, Peter; Vannberg, Fredrik

    2014-01-01

    Motivation: Converting nucleotide sequences into short overlapping fragments of uniform length, k-mers, is a common step in many bioinformatics applications. While existing software packages count k-mers, few are optimized for speed, offer an application programming interface (API), a graphical interface or contain features that make it extensible and maintainable. We designed KAnalyze to compete with the fastest k-mer counters, to produce reliable output and to support future development efforts through well-architected, documented and testable code. Currently, KAnalyze can output k-mer counts in a sorted tab-delimited file or stream k-mers as they are read. KAnalyze can process large datasets with 2 GB of memory. This project is implemented in Java 7, and the command line interface (CLI) is designed to integrate into pipelines written in any language. Results: As a k-mer counter, KAnalyze outperforms Jellyfish, DSK and a pipeline built on Perl and Linux utilities. Through extensive unit and system testing, we have verified that KAnalyze produces the correct k-mer counts over multiple datasets and k-mer sizes. Availability and implementation: KAnalyze is available on SourceForge: https://sourceforge.net/projects/kanalyze/ Contact: fredrik.vannberg@biology.gatech.edu Supplementary information: Supplementary data are available at Bioinformatics online. PMID:24642064

  16. KAnalyze: a fast versatile pipelined k-mer toolkit.

    PubMed

    Audano, Peter; Vannberg, Fredrik

    2014-07-15

    Converting nucleotide sequences into short overlapping fragments of uniform length, k-mers, is a common step in many bioinformatics applications. While existing software packages count k-mers, few are optimized for speed, offer an application programming interface (API), a graphical interface or contain features that make it extensible and maintainable. We designed KAnalyze to compete with the fastest k-mer counters, to produce reliable output and to support future development efforts through well-architected, documented and testable code. Currently, KAnalyze can output k-mer counts in a sorted tab-delimited file or stream k-mers as they are read. KAnalyze can process large datasets with 2 GB of memory. This project is implemented in Java 7, and the command line interface (CLI) is designed to integrate into pipelines written in any language. As a k-mer counter, KAnalyze outperforms Jellyfish, DSK and a pipeline built on Perl and Linux utilities. Through extensive unit and system testing, we have verified that KAnalyze produces the correct k-mer counts over multiple datasets and k-mer sizes. KAnalyze is available on SourceForge: https://sourceforge.net/projects/kanalyze/. © The Author 2014. Published by Oxford University Press.

  17. A collection of open source applications for mass spectrometry data mining.

    PubMed

    Gallardo, Óscar; Ovelleiro, David; Gay, Marina; Carrascal, Montserrat; Abian, Joaquin

    2014-10-01

    We present several bioinformatics applications for the identification and quantification of phosphoproteome components by MS. These applications include a front-end graphical user interface that combines several Thermo RAW formats to MASCOT™ Generic Format extractors (EasierMgf), two graphical user interfaces for search engines OMSSA and SEQUEST (OmssaGui and SequestGui), and three applications, one for the management of databases in FASTA format (FastaTools), another for the integration of search results from up to three search engines (Integrator), and another one for the visualization of mass spectra and their corresponding database search results (JsonVisor). These applications were developed to solve some of the common problems found in proteomic and phosphoproteomic data analysis and were integrated in the workflow for data processing and feeding on our LymPHOS database. Applications were designed modularly and can be used standalone. These tools are written in Perl and Python programming languages and are supported on Windows platforms. They are all released under an Open Source Software license and can be freely downloaded from our software repository hosted at GoogleCode. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. The CEBAF Element Database

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Theodore Larrieu, Christopher Slominski, Michele Joyce

    2011-03-01

    With the inauguration of the CEBAF Element Database (CED) in Fall 2010, Jefferson Lab computer scientists have taken a step toward the eventual goal of a model-driven accelerator. Once fully populated, the database will be the primary repository of information used for everything from generating lattice decks to booting control computers to building controls screens. A requirement influencing the CED design is that it provide access to not only present, but also future and past configurations of the accelerator. To accomplish this, an introspective database schema was designed that allows new elements, types, and properties to be defined on-the-fly withmore » no changes to table structure. Used in conjunction with Oracle Workspace Manager, it allows users to query data from any time in the database history with the same tools used to query the present configuration. Users can also check-out workspaces to use as staging areas for upcoming machine configurations. All Access to the CED is through a well-documented Application Programming Interface (API) that is translated automatically from original C++ source code into native libraries for scripting languages such as perl, php, and TCL making access to the CED easy and ubiquitous.« less

  19. Comparison of Rogers, Perls, and Ellis on the Hill Counselor Verbal Response Category System.

    ERIC Educational Resources Information Center

    Hill, Clara E.; And Others

    1979-01-01

    Analyzes transcripts of films of Rogers, Perls, and Ellis counseling the same client, according to the Hill Counselor Verbal Response Category System. The system described verbal behaviors of the three counselors and detected behavioral differences reflective of their differing theoretical orientations. (Author)

  20. Writing (ONLINE) Space: Composing Webware in Perl.

    ERIC Educational Resources Information Center

    Hartley, Cecilia; Schendel, Ellen; Neal, Michael R.

    1999-01-01

    Points to scholarship that helped the authors think about the ideologies behind Writing Spaces, a Web-based site for computer-mediated communication that they constructed using Perl scripts. Argues that writing teachers can and should shape online spaces to facilitate their individual pedagogies rather than allowing commercial software to limit…

  1. PACCE: Perl Algorithm to Compute Continuum and Equivalent Widths

    NASA Astrophysics Data System (ADS)

    Riffel, Rogério; Borges Vale, Tibério

    2011-05-01

    PACCE (Perl Algorithm to Compute continuum and Equivalent Widths) computes continuum and equivalent widths. PACCE is able to determine mean continuum and continuum at line center values, which are helpful in stellar population studies, and is also able to compute the uncertainties in the equivalent widths using photon statistics.

  2. Improvement of web-based data acquisition and management system for GOSAT validation lidar data analysis

    NASA Astrophysics Data System (ADS)

    Okumura, Hiroshi; Takubo, Shoichiro; Kawasaki, Takeru; Abdullah, Indra Nugraha; Uchino, Osamu; Morino, Isamu; Yokota, Tatsuya; Nagai, Tomohiro; Sakai, Tetsu; Maki, Takashi; Arai, Kohei

    2013-01-01

    A web-base data acquisition and management system for GOSAT (Greenhouse gases Observation SATellite) validation lidar data-analysis has been developed. The system consists of data acquisition sub-system (DAS) and data management sub-system (DMS). DAS written in Perl language acquires AMeDAS (Automated Meteorological Data Acquisition System) ground-level local meteorological data, GPS Radiosonde upper-air meteorological data, ground-level oxidant data, skyradiometer data, skyview camera images, meteorological satellite IR image data and GOSAT validation lidar data. DMS written in PHP language demonstrates satellite-pass date and all acquired data. In this article, we briefly describe some improvement for higher performance and higher data usability. GPS Radiosonde upper-air meteorological data and U.S. standard atmospheric model in DAS automatically calculate molecule number density profiles. Predicted ozone density prole images above Saga city are also calculated by using Meteorological Research Institute (MRI) chemistry-climate model version 2 for comparison to actual ozone DIAL data.

  3. [A customized method for information extraction from unstructured text data in the electronic medical records].

    PubMed

    Bao, X Y; Huang, W J; Zhang, K; Jin, M; Li, Y; Niu, C Z

    2018-04-18

    There is a huge amount of diagnostic or treatment information in electronic medical record (EMR), which is a concrete manifestation of clinicians actual diagnosis and treatment details. Plenty of episodes in EMRs, such as complaints, present illness, past history, differential diagnosis, diagnostic imaging, surgical records, reflecting details of diagnosis and treatment in clinical process, adopt Chinese description of natural language. How to extract effective information from these Chinese narrative text data, and organize it into a form of tabular for analysis of medical research, for the practical utilization of clinical data in the real world, is a difficult problem in Chinese medical data processing. Based on the EMRs narrative text data in a tertiary hospital in China, a customized information extracting rules learning, and rule based information extraction methods is proposed. The overall method consists of three steps, which includes: (1) Step 1, a random sample of 600 copies (including the history of present illness, past history, personal history, family history, etc.) of the electronic medical record data, was extracted as raw corpora. With our developed Chinese clinical narrative text annotation platform, the trained clinician and nurses marked the tokens and phrases in the corpora which would be extracted (with a history of diabetes as an example). (2) Step 2, based on the annotated corpora clinical text data, some extraction templates were summarized and induced firstly. Then these templates were rewritten using regular expressions of Perl programming language, as extraction rules. Using these extraction rules as basic knowledge base, we developed extraction packages in Perl, for extracting data from the EMRs text data. In the end, the extracted data items were organized in tabular data format, for later usage in clinical research or hospital surveillance purposes. (3) As the final step of the method, the evaluation and validation of the proposed methods were implemented in the National Clinical Service Data Integration Platform, and we checked the extraction results using artificial verification and automated verification combined, proved the effectiveness of the method. For all the patients with diabetes as diagnosed disease in the Department of Endocrine in the hospital, the medical history episode of these patients showed that, altogether 1 436 patients were dismissed in 2015, and a history of diabetes medical records extraction results showed that the recall rate was 87.6%, the accuracy rate was 99.5%, and F-Score was 0.93. For all the 10% patients (totally 1 223 patients) with diabetes by the dismissed dates of August 2017 in the same department, the extracted diabetes history extraction results showed that the recall rate was 89.2%, the accuracy rate was 99.2%, F-Score was 0.94. This study mainly adopts the combination of natural language processing and rule-based information extraction, and designs and implements an algorithm for extracting customized information from unstructured Chinese electronic medical record text data. It has better results than existing work.

  4. The program LOPT for least-squares optimization of energy levels

    NASA Astrophysics Data System (ADS)

    Kramida, A. E.

    2011-02-01

    The article describes a program that solves the least-squares optimization problem for finding the energy levels of a quantum-mechanical system based on a set of measured energy separations or wavelengths of transitions between those energy levels, as well as determining the Ritz wavelengths of transitions and their uncertainties. The energy levels are determined by solving the matrix equation of the problem, and the uncertainties of the Ritz wavenumbers are determined from the covariance matrix of the problem. Program summaryProgram title: LOPT Catalogue identifier: AEHM_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEHM_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 19 254 No. of bytes in distributed program, including test data, etc.: 427 839 Distribution format: tar.gz Programming language: Perl v.5 Computer: PC, Mac, Unix workstations Operating system: MS Windows (XP, Vista, 7), Mac OS X, Linux, Unix (AIX) RAM: 3 Mwords or more Word size: 32 or 64 Classification: 2.2 Nature of problem: The least-squares energy-level optimization problem, i.e., finding a set of energy level values that best fits the given set of transition intervals. Solution method: The solution of the least-squares problem is found by solving the corresponding linear matrix equation, where the matrix is constructed using a new method with variable substitution. Restrictions: A practical limitation on the size of the problem N is imposed by the execution time, which scales as N and depends on the computer. Unusual features: Properly rounds the resulting data and formats the output in a format suitable for viewing with spreadsheet editing software. Estimates numerical errors resulting from the limited machine precision. Running time: 1 s for N=100, or 60 s for N=400 on a typical PC.

  5. AlleleCoder: a PERL script for coding codominant polymorphism data for PCA analysis

    USDA-ARS?s Scientific Manuscript database

    A useful biological interpretation of diploid heterozygotes is in terms of the dose of the common allele (0, 1 or 2 copies). We have developed a PERL script that converts FASTA files into coded spreadsheets suitable for Principal Component Analysis (PCA). In combination with R and R Commander, two- ...

  6. Good Moments in Gestalt Therapy: A Descriptive Analysis of Two Perls Sessions.

    ERIC Educational Resources Information Center

    Boulet, Donald; And Others

    1993-01-01

    Analyzed two Gestalt therapy sessions conducted by Fritz Perls using category system for identifying in-session client behaviors valued by Gestalt therapists. Four judges independently rated 210 client statements. Found common pattern of therapeutic movement: initial phase dominated by building block good moments and second phase characterized by…

  7. Strategies for single-point diamond machining a large format germanium blazed immersion grating

    NASA Astrophysics Data System (ADS)

    Montesanti, R. C.; Little, S. L.; Kuzmenko, P. J.; Bixler, J. V.; Jackson, J. L.; Lown, J. G.; Priest, R. E.; Yoxall, B. E.

    2016-07-01

    A large format germanium immersion grating was flycut with a single-point diamond tool on the Precision Engineering Research Lathe (PERL) at the Lawrence Livermore National Laboratory (LLNL) in November - December 2015. The grating, referred to as 002u, has an area of 59 mm x 67 mm (along-groove and cross-groove directions), line pitch of 88 line/mm, and blaze angle of 32 degree. Based on total groove length, the 002u grating is five times larger than the previous largest grating (ZnSe) cut on PERL, and forty-five times larger than the previous largest germanium grating cut on PERL. The key risks associated with cutting the 002u grating were tool wear and keeping the PERL machine running uninterrupted in a stable machining environment. This paper presents the strategies employed to mitigate these risks, introduces pre-machining of the as-etched grating substrate to produce a smooth, flat, damage-free surface into which the grooves are cut, and reports on trade-offs that drove decisions and experimental results.

  8. KBWS: an EMBOSS associated package for accessing bioinformatics web services.

    PubMed

    Oshita, Kazuki; Arakawa, Kazuharu; Tomita, Masaru

    2011-04-29

    The availability of bioinformatics web-based services is rapidly proliferating, for their interoperability and ease of use. The next challenge is in the integration of these services in the form of workflows, and several projects are already underway, standardizing the syntax, semantics, and user interfaces. In order to deploy the advantages of web services with locally installed tools, here we describe a collection of proxy client tools for 42 major bioinformatics web services in the form of European Molecular Biology Open Software Suite (EMBOSS) UNIX command-line tools. EMBOSS provides sophisticated means for discoverability and interoperability for hundreds of tools, and our package, named the Keio Bioinformatics Web Service (KBWS), adds functionalities of local and multiple alignment of sequences, phylogenetic analyses, and prediction of cellular localization of proteins and RNA secondary structures. This software implemented in C is available under GPL from http://www.g-language.org/kbws/ and GitHub repository http://github.com/cory-ko/KBWS. Users can utilize the SOAP services implemented in Perl directly via WSDL file at http://soap.g-language.org/kbws.wsdl (RPC Encoded) and http://soap.g-language.org/kbws_dl.wsdl (Document/literal).

  9. Using Perls Staining to Trace the Iron Uptake Pathway in Leaves of a Prunus Rootstock Treated with Iron Foliar Fertilizers

    PubMed Central

    Rios, Juan J.; Carrasco-Gil, Sandra; Abadía, Anunciación; Abadía, Javier

    2016-01-01

    The aim of this study was to trace the Fe uptake pathway in leaves of Prunus rootstock (GF 677; Prunus dulcis × Prunus persica) plants treated with foliar Fe compounds using the Perls blue method, which detects labile Fe pools. Young expanded leaves of Fe-deficient plants grown in nutrient solution were treated with Fe-compounds using a brush. Iron compounds used were the ferrous salt FeSO4, the ferric salts Fe2(SO4)3 and FeCl3, and the chelate Fe(III)-EDTA, all of them at concentrations of 9 mM Fe. Leaf Fe concentration increases were measured at 30, 60, 90 min, and 24 h, and 70 μm-thick leaf transversal sections were obtained with a vibrating microtome and stained with Perls blue. In vitro results show that the Perls blue method is a good tool to trace the Fe uptake pathway in leaves when using Fe salts, but is not sensitive enough when using synthetic Fe(III)-chelates such as Fe(III)-EDTA and Fe(III)-IDHA. Foliar Fe fertilization increased leaf Fe concentrations with all Fe compounds used, with inorganic Fe salts causing larger leaf Fe concentration increases than Fe(III)-EDTA. Results show that Perls blue stain appeared within 30 min in the stomatal areas, indicating that Fe applied as inorganic salts was taken up rapidly via stomata. In the case of using FeSO4 a progression of the stain was seen with time toward vascular areas in the leaf blade and the central vein, whereas in the case of Fe(III) salts the stain mainly remained in the stomatal areas. Perls stain was never observed in the mesophyll areas, possibly due to the low concentration of labile Fe pools. PMID:27446123

  10. The Evaluation of Filmed Excerpts of Rogers, Perls, and Ellis by Beginning Counselor Trainees

    ERIC Educational Resources Information Center

    Kelly, F. Donald; Byrne, Thomas P.

    1977-01-01

    Students (N=29) viewed three stimulus films and rated therapeutic effectiveness of the therapists. Students were subsequently rank-ordered on the basis of skill development and assigned to one of three groups (high, middle, or low.) Results revealed an overall higher evaluation for Rogers as compared to either Perls or Ellis. (Author)

  11. Transition to a Unified System: Using Perl To Drive Library Databases and Enhance Web Site Functionality.

    ERIC Educational Resources Information Center

    Fagan, Judy Condit

    2001-01-01

    Discusses the need for libraries to routinely redesign their Web sites, and presents a case study that describes how a Perl-driven database at Southern Illinois University's library improved Web site organization and patron access, simplified revisions, and allowed staff unfamiliar with HTML to update content. (Contains 56 references.) (Author/LRW)

  12. Automated Sequence Processor: Something Old, Something New

    NASA Technical Reports Server (NTRS)

    Streiffert, Barbara; Schrock, Mitchell; Fisher, Forest; Himes, Terry

    2012-01-01

    High productivity required for operations teams to meet schedules Risk must be minimized. Scripting used to automate processes. Scripts perform essential operations functions. Automated Sequence Processor (ASP) was a grass-roots task built to automate the command uplink process System engineering task for ASP revitalization organized. ASP is a set of approximately 200 scripts written in Perl, C Shell, AWK and other scripting languages.. ASP processes/checks/packages non-interactive commands automatically.. Non-interactive commands are guaranteed to be safe and have been checked by hardware or software simulators.. ASP checks that commands are non-interactive.. ASP processes the commands through a command. simulator and then packages them if there are no errors.. ASP must be active 24 hours/day, 7 days/week..

  13. BiDiBlast: comparative genomics pipeline for the PC.

    PubMed

    de Almeida, João M G C F

    2010-06-01

    Bi-directional BLAST is a simple approach to detect, annotate, and analyze candidate orthologous or paralogous sequences in a single go. This procedure is usually confined to the realm of customized Perl scripts, usually tuned for UNIX-like environments. Porting those scripts to other operating systems involves refactoring them, and also the installation of the Perl programming environment with the required libraries. To overcome these limitations, a data pipeline was implemented in Java. This application submits two batches of sequences to local versions of the NCBI BLAST tool, manages result lists, and refines both bi-directional and simple hits. GO Slim terms are attached to hits, several statistics are derived, and molecular evolution rates are estimated through PAML. The results are written to a set of delimited text tables intended for further analysis. The provided graphic user interface allows a friendly interaction with this application, which is documented and available to download at http://moodle.fct.unl.pt/course/view.php?id=2079 or https://sourceforge.net/projects/bidiblast/ under the GNU GPL license. Copyright 2010 Beijing Genomics Institute. Published by Elsevier Ltd. All rights reserved.

  14. Automated Alerting for Black Hole Routing

    DTIC Science & Technology

    2007-09-01

    Beginners or Learning Bro). Reply: Just the documentation that comes with it and is available from the wiki. Question 4: Is Bro compatible with...other scripts written in Python , Java, or Perl? Reply: It can call arbitrary programs but doesn’t link directly into other interpreters. Question 5...need to write that daemon? (C) What kind of scripts does Spunk support…and are Python and C part of them or not? 88 Reply: Puri, the answers to all

  15. PeRL: a circum-Arctic Permafrost Region Pond and Lake database

    NASA Astrophysics Data System (ADS)

    Muster, Sina; Roth, Kurt; Langer, Moritz; Lange, Stephan; Cresto Aleina, Fabio; Bartsch, Annett; Morgenstern, Anne; Grosse, Guido; Jones, Benjamin; Sannel, A. Britta K.; Sjöberg, Ylva; Günther, Frank; Andresen, Christian; Veremeeva, Alexandra; Lindgren, Prajna R.; Bouchard, Frédéric; Lara, Mark J.; Fortier, Daniel; Charbonneau, Simon; Virtanen, Tarmo A.; Hugelius, Gustaf; Palmtag, Juri; Siewert, Matthias B.; Riley, William J.; Koven, Charles D.; Boike, Julia

    2017-06-01

    Ponds and lakes are abundant in Arctic permafrost lowlands. They play an important role in Arctic wetland ecosystems by regulating carbon, water, and energy fluxes and providing freshwater habitats. However, ponds, i.e., waterbodies with surface areas smaller than 1. 0 × 104 m2, have not been inventoried on global and regional scales. The Permafrost Region Pond and Lake (PeRL) database presents the results of a circum-Arctic effort to map ponds and lakes from modern (2002-2013) high-resolution aerial and satellite imagery with a resolution of 5 m or better. The database also includes historical imagery from 1948 to 1965 with a resolution of 6 m or better. PeRL includes 69 maps covering a wide range of environmental conditions from tundra to boreal regions and from continuous to discontinuous permafrost zones. Waterbody maps are linked to regional permafrost landscape maps which provide information on permafrost extent, ground ice volume, geology, and lithology. This paper describes waterbody classification and accuracy, and presents statistics of waterbody distribution for each site. Maps of permafrost landscapes in Alaska, Canada, and Russia are used to extrapolate waterbody statistics from the site level to regional landscape units. PeRL presents pond and lake estimates for a total area of 1. 4 × 106 km2 across the Arctic, about 17 % of the Arctic lowland ( < 300 m a.s.l.) land surface area. PeRL waterbodies with sizes of 1. 0 × 106 m2 down to 1. 0 × 102 m2 contributed up to 21 % to the total water fraction. Waterbody density ranged from 1. 0 × 10 to 9. 4 × 101 km-2. Ponds are the dominant waterbody type by number in all landscapes representing 45-99 % of the total waterbody number. The implementation of PeRL size distributions in land surface models will greatly improve the investigation and projection of surface inundation and carbon fluxes in permafrost lowlands. Waterbody maps, study area boundaries, and maps of regional permafrost landscapes including detailed metadata are available at https://doi.pangaea.de/10.1594/PANGAEA.868349.

  16. PeRL: a circum-Arctic Permafrost Region Pond and Lake database

    DOE PAGES

    Muster, Sina; Roth, Kurt; Langer, Moritz; ...

    2017-06-06

    Ponds and lakes are abundant in Arctic permafrost lowlands. They play an important role in Arctic wetland ecosystems by regulating carbon, water, and energy fluxes and providing freshwater habitats. However, ponds, i.e., waterbodies with surface areas smaller than 1.0 × 10 4 m 2, have not been inventoried on global and regional scales. The Permafrost Region Pond and Lake (PeRL) database presents the results of a circum-Arctic effort to map ponds and lakes from modern (2002–2013) high-resolution aerial and satellite imagery with a resolution of 5 m or better. The database also includes historical imagery from 1948 to 1965 withmore » a resolution of 6 m or better. PeRL includes 69 maps covering a wide range of environmental conditions from tundra to boreal regions and from continuous to discontinuous permafrost zones. Waterbody maps are linked to regional permafrost landscape maps which provide information on permafrost extent, ground ice volume, geology, and lithology. This paper describes waterbody classification and accuracy, and presents statistics of waterbody distribution for each site. Maps of permafrost landscapes in Alaska, Canada, and Russia are used to extrapolate waterbody statistics from the site level to regional landscape units. PeRL presents pond and lake estimates for a total area of 1.4 × 10 6 km 2 across the Arctic, about 17 % of the Arctic lowland ( < 300 m a.s.l.) land surface area. PeRL waterbodies with sizes of 1.0 ×10 6 m 2 down to 1.0 ×10 2 m 2 contributed up to 21 % to the total water fraction. Waterbody density ranged from 1.0 ×10 to 9.4 × 10 1 km –2. Ponds are the dominant waterbody type by number in all landscapes representing 45–99 % of the total waterbody number. In conclusion, the implementation of PeRL size distributions in land surface models will greatly improve the investigation and projection of surface inundation and carbon fluxes in permafrost lowlands.« less

  17. PeRL: a circum-Arctic Permafrost Region Pond and Lake database

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Muster, Sina; Roth, Kurt; Langer, Moritz

    Ponds and lakes are abundant in Arctic permafrost lowlands. They play an important role in Arctic wetland ecosystems by regulating carbon, water, and energy fluxes and providing freshwater habitats. However, ponds, i.e., waterbodies with surface areas smaller than 1.0 × 10 4 m 2, have not been inventoried on global and regional scales. The Permafrost Region Pond and Lake (PeRL) database presents the results of a circum-Arctic effort to map ponds and lakes from modern (2002–2013) high-resolution aerial and satellite imagery with a resolution of 5 m or better. The database also includes historical imagery from 1948 to 1965 withmore » a resolution of 6 m or better. PeRL includes 69 maps covering a wide range of environmental conditions from tundra to boreal regions and from continuous to discontinuous permafrost zones. Waterbody maps are linked to regional permafrost landscape maps which provide information on permafrost extent, ground ice volume, geology, and lithology. This paper describes waterbody classification and accuracy, and presents statistics of waterbody distribution for each site. Maps of permafrost landscapes in Alaska, Canada, and Russia are used to extrapolate waterbody statistics from the site level to regional landscape units. PeRL presents pond and lake estimates for a total area of 1.4 × 10 6 km 2 across the Arctic, about 17 % of the Arctic lowland ( < 300 m a.s.l.) land surface area. PeRL waterbodies with sizes of 1.0 ×10 6 m 2 down to 1.0 ×10 2 m 2 contributed up to 21 % to the total water fraction. Waterbody density ranged from 1.0 ×10 to 9.4 × 10 1 km –2. Ponds are the dominant waterbody type by number in all landscapes representing 45–99 % of the total waterbody number. In conclusion, the implementation of PeRL size distributions in land surface models will greatly improve the investigation and projection of surface inundation and carbon fluxes in permafrost lowlands.« less

  18. Python as a federation tool for GENESIS 3.0.

    PubMed

    Cornelis, Hugo; Rodriguez, Armando L; Coop, Allan D; Bower, James M

    2012-01-01

    The GENESIS simulation platform was one of the first broad-scale modeling systems in computational biology to encourage modelers to develop and share model features and components. Supported by a large developer community, it participated in innovative simulator technologies such as benchmarking, parallelization, and declarative model specification and was the first neural simulator to define bindings for the Python scripting language. An important feature of the latest version of GENESIS is that it decomposes into self-contained software components complying with the Computational Biology Initiative federated software architecture. This architecture allows separate scripting bindings to be defined for different necessary components of the simulator, e.g., the mathematical solvers and graphical user interface. Python is a scripting language that provides rich sets of freely available open source libraries. With clean dynamic object-oriented designs, they produce highly readable code and are widely employed in specialized areas of software component integration. We employ a simplified wrapper and interface generator to examine an application programming interface and make it available to a given scripting language. This allows independent software components to be 'glued' together and connected to external libraries and applications from user-defined Python or Perl scripts. We illustrate our approach with three examples of Python scripting. (1) Generate and run a simple single-compartment model neuron connected to a stand-alone mathematical solver. (2) Interface a mathematical solver with GENESIS 3.0 to explore a neuron morphology from either an interactive command-line or graphical user interface. (3) Apply scripting bindings to connect the GENESIS 3.0 simulator to external graphical libraries and an open source three dimensional content creation suite that supports visualization of models based on electron microscopy and their conversion to computational models. Employed in this way, the stand-alone software components of the GENESIS 3.0 simulator provide a framework for progressive federated software development in computational neuroscience.

  19. Python as a Federation Tool for GENESIS 3.0

    PubMed Central

    Cornelis, Hugo; Rodriguez, Armando L.; Coop, Allan D.; Bower, James M.

    2012-01-01

    The GENESIS simulation platform was one of the first broad-scale modeling systems in computational biology to encourage modelers to develop and share model features and components. Supported by a large developer community, it participated in innovative simulator technologies such as benchmarking, parallelization, and declarative model specification and was the first neural simulator to define bindings for the Python scripting language. An important feature of the latest version of GENESIS is that it decomposes into self-contained software components complying with the Computational Biology Initiative federated software architecture. This architecture allows separate scripting bindings to be defined for different necessary components of the simulator, e.g., the mathematical solvers and graphical user interface. Python is a scripting language that provides rich sets of freely available open source libraries. With clean dynamic object-oriented designs, they produce highly readable code and are widely employed in specialized areas of software component integration. We employ a simplified wrapper and interface generator to examine an application programming interface and make it available to a given scripting language. This allows independent software components to be ‘glued’ together and connected to external libraries and applications from user-defined Python or Perl scripts. We illustrate our approach with three examples of Python scripting. (1) Generate and run a simple single-compartment model neuron connected to a stand-alone mathematical solver. (2) Interface a mathematical solver with GENESIS 3.0 to explore a neuron morphology from either an interactive command-line or graphical user interface. (3) Apply scripting bindings to connect the GENESIS 3.0 simulator to external graphical libraries and an open source three dimensional content creation suite that supports visualization of models based on electron microscopy and their conversion to computational models. Employed in this way, the stand-alone software components of the GENESIS 3.0 simulator provide a framework for progressive federated software development in computational neuroscience. PMID:22276101

  20. Packaging Software Assets for Reuse

    NASA Astrophysics Data System (ADS)

    Mattmann, C. A.; Marshall, J. J.; Downs, R. R.

    2010-12-01

    The reuse of existing software assets such as code, architecture, libraries, and modules in current software and systems development projects can provide many benefits, including reduced costs, in time and effort, and increased reliability. Many reusable assets are currently available in various online catalogs and repositories, usually broken down by disciplines such as programming language (Ibiblio for Maven/Java developers, PyPI for Python developers, CPAN for Perl developers, etc.). The way these assets are packaged for distribution can play a role in their reuse - an asset that is packaged simply and logically is typically easier to understand, install, and use, thereby increasing its reusability. A well-packaged asset has advantages in being more reusable and thus more likely to provide benefits through its reuse. This presentation will discuss various aspects of software asset packaging and how they can affect the reusability of the assets. The characteristics of well-packaged software will be described. A software packaging domain model will be introduced, and some existing packaging approaches examined. An example case study of a Reuse Enablement System (RES), currently being created by near-term Earth science decadal survey missions, will provide information about the use of the domain model. Awareness of these factors will help software developers package their reusable assets so that they can provide the most benefits for software reuse.

  1. Test case for VVER-1000 complex modeling using MCU and ATHLET

    NASA Astrophysics Data System (ADS)

    Bahdanovich, R. B.; Bogdanova, E. V.; Gamtsemlidze, I. D.; Nikonov, S. P.; Tikhomirov, G. V.

    2017-01-01

    The correct modeling of processes occurring in the fuel core of the reactor is very important. In the design and operation of nuclear reactors it is necessary to cover the entire range of reactor physics. Very often the calculations are carried out within the framework of only one domain, for example, in the framework of structural analysis, neutronics (NT) or thermal hydraulics (TH). However, this is not always correct, as the impact of related physical processes occurring simultaneously, could be significant. Therefore it is recommended to spend the coupled calculations. The paper provides test case for the coupled neutronics-thermal hydraulics calculation of VVER-1000 using the precise neutron code MCU and system engineering code ATHLET. The model is based on the fuel assembly (type 2M). Test case for calculation of power distribution, fuel and coolant temperature, coolant density, etc. has been developed. It is assumed that the test case will be used for simulation of VVER-1000 reactor and in the calculation using other programs, for example, for codes cross-verification. The detailed description of the codes (MCU, ATHLET), geometry and material composition of the model and an iterative calculation scheme is given in the paper. Script in PERL language was written to couple the codes.

  2. Monitoring Temperature and Fan Speed Using Ganglia and Winbond Chips

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McCaffrey, Cattie; /SLAC

    2006-09-27

    Effective monitoring is essential to keep a large group of machines, like the ones at Stanford Linear Accelerator Center (SLAC), up and running. SLAC currently uses Ganglia Monitoring System to observe about 2000 machines, analyzing metrics like CPU usage and I/O rate. However, metrics essential to machine hardware health, such as temperature and fan speed, are not being monitored. Many machines have a Winbond w83782d chip which monitors three temperatures, two of which come from dual CPUs, and returns the information when the sensor command is invoked. Ganglia also provides a feature, gmetric, that allows the users to monitor theirmore » own metrics and incorporate them into the monitoring system. The programming language Perl is chosen to implement a script that invokes the sensors command, extracts the temperature and fan speed information, and calls gmetric with the appropriate arguments. Two machines were used to test the script; the two CPUs on each machine run at about 65 Celsius, which is well within the operating temperature range (The maximum safe temperature range is 77-82 Celsius for the Pentium III processors being used). Installing the script on all machines with a Winbond w83782d chip allows the SLAC Scientific Computing and Computing Services group (SCCS) to better evaluate current cooling methods.« less

  3. Semantic-JSON: a lightweight web service interface for Semantic Web contents integrating multiple life science databases.

    PubMed

    Kobayashi, Norio; Ishii, Manabu; Takahashi, Satoshi; Mochizuki, Yoshiki; Matsushima, Akihiro; Toyoda, Tetsuro

    2011-07-01

    Global cloud frameworks for bioinformatics research databases become huge and heterogeneous; solutions face various diametric challenges comprising cross-integration, retrieval, security and openness. To address this, as of March 2011 organizations including RIKEN published 192 mammalian, plant and protein life sciences databases having 8.2 million data records, integrated as Linked Open or Private Data (LOD/LPD) using SciNetS.org, the Scientists' Networking System. The huge quantity of linked data this database integration framework covers is based on the Semantic Web, where researchers collaborate by managing metadata across public and private databases in a secured data space. This outstripped the data query capacity of existing interface tools like SPARQL. Actual research also requires specialized tools for data analysis using raw original data. To solve these challenges, in December 2009 we developed the lightweight Semantic-JSON interface to access each fragment of linked and raw life sciences data securely under the control of programming languages popularly used by bioinformaticians such as Perl and Ruby. Researchers successfully used the interface across 28 million semantic relationships for biological applications including genome design, sequence processing, inference over phenotype databases, full-text search indexing and human-readable contents like ontology and LOD tree viewers. Semantic-JSON services of SciNetS.org are provided at http://semanticjson.org.

  4. FAST: FAST Analysis of Sequences Toolbox

    PubMed Central

    Lawrence, Travis J.; Kauffman, Kyle T.; Amrine, Katherine C. H.; Carper, Dana L.; Lee, Raymond S.; Becich, Peter J.; Canales, Claudia J.; Ardell, David H.

    2015-01-01

    FAST (FAST Analysis of Sequences Toolbox) provides simple, powerful open source command-line tools to filter, transform, annotate and analyze biological sequence data. Modeled after the GNU (GNU's Not Unix) Textutils such as grep, cut, and tr, FAST tools such as fasgrep, fascut, and fastr make it easy to rapidly prototype expressive bioinformatic workflows in a compact and generic command vocabulary. Compact combinatorial encoding of data workflows with FAST commands can simplify the documentation and reproducibility of bioinformatic protocols, supporting better transparency in biological data science. Interface self-consistency and conformity with conventions of GNU, Matlab, Perl, BioPerl, R, and GenBank help make FAST easy and rewarding to learn. FAST automates numerical, taxonomic, and text-based sorting, selection and transformation of sequence records and alignment sites based on content, index ranges, descriptive tags, annotated features, and in-line calculated analytics, including composition and codon usage. Automated content- and feature-based extraction of sites and support for molecular population genetic statistics make FAST useful for molecular evolutionary analysis. FAST is portable, easy to install and secure thanks to the relative maturity of its Perl and BioPerl foundations, with stable releases posted to CPAN. Development as well as a publicly accessible Cookbook and Wiki are available on the FAST GitHub repository at https://github.com/tlawrence3/FAST. The default data exchange format in FAST is Multi-FastA (specifically, a restriction of BioPerl FastA format). Sanger and Illumina 1.8+ FastQ formatted files are also supported. FAST makes it easier for non-programmer biologists to interactively investigate and control biological data at the speed of thought. PMID:26042145

  5. PERLE. Powerful energy recovery linac for experiments. Conceptual design report

    NASA Astrophysics Data System (ADS)

    Angal-Kalinin, D.; Arduini, G.; Auchmann, B.; Bernauer, J.; Bogacz, A.; Bordry, F.; Bousson, S.; Bracco, C.; Brüning, O.; Calaga, R.; Cassou, K.; Chetvertkova, V.; Cormier, E.; Daly, E.; Douglas, D.; Dupraz, K.; Goddard, B.; Henry, J.; Hutton, A.; Jensen, E.; Kaabi, W.; Klein, M.; Kostka, P.; Lasheras, N.; Levichev, E.; Marhauser, F.; Martens, A.; Milanese, A.; Militsyn, B.; Peinaud, Y.; Pellegrini, D.; Pietralla, N.; Pupkov, Y.; Rimmer, R.; Schirm, K.; Schulte, D.; Smith, S.; Stocchi, A.; Valloni, A.; Welsch, C.; Willering, G.; Wollmann, D.; Zimmermann, F.; Zomer, F.

    2018-06-01

    A conceptual design is presented of a novel energy-recovering linac (ERL) facility for the development and application of the energy recovery technique to linear electron accelerators in the multi-turn, large current and large energy regime. The main characteristics of the powerful energy recovery linac experiment facility (PERLE) are derived from the design of the Large Hadron electron Collider, an electron beam upgrade under study for the LHC, for which it would be the key demonstrator. PERLE is thus projected as a facility to investigate efficient, high current (HC) (>10 mA) ERL operation with three re-circulation passages through newly designed SCRF cavities, at 801.58 MHz frequency, and following deceleration over another three re-circulations. In its fully equipped configuration, PERLE provides an electron beam of approximately 1 GeV energy. A physics programme possibly associated with PERLE is sketched, consisting of high precision elastic electron–proton scattering experiments, as well as photo-nuclear reactions of unprecedented intensities with up to 30 MeV photon beam energy as may be obtained using Fabry–Perot cavities. The facility has further applications as a general technology test bed that can investigate and validate novel superconducting magnets (beam induced quench tests) and superconducting RF structures (structure tests with HC beams, beam loading and transients). Besides a chapter on operation aspects, the report contains detailed considerations on the choices for the SCRF structure, optics and lattice design, solutions for arc magnets, source and injector and on further essential components. A suitable configuration derived from the here presented design concept may next be moved forward to a technical design and possibly be built by an international collaboration which is being established.

  6. Report on IVS-WG4

    NASA Astrophysics Data System (ADS)

    Gipson, John

    2011-07-01

    I describe the proposed data structure for storing, archiving and processing VLBI data. In this scheme, most VLBI data is stored in NetCDF files. NetCDF has the advantage that there are interfaces to most common computer languages including Fortran, Fortran-90, C, C++, Perl, etc, and the most common operating systems including linux, Windows and Mac. The data files for a particular session are organized by special ASCII "wrapper" files which contain pointers to the data files. This allows great flexibility in the processing and analysis of VLBI data, and also allows for extending the types of data used, e.g., source maps. I discuss the use of the new format in calc/solve and other VLBI analysis packages. I also discuss plans for transitioning to the new structure.

  7. System for NIS Forecasting Based on Ensembles Analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    2014-01-02

    BMA-NIS is a package/library designed to be called by a script (e.g. Perl or Python). The software itself is written in the language of R. The software assists electric power delivery systems in planning resource availability and demand, based on historical data and current data variables. Net Interchange Schedule (NIS) is the algebraic sum of all energy scheduled to flow into or out of a balancing area during any interval. Accurate forecasts for NIS are important so that the Area Control Error (ACE) stays within an acceptable limit. To date, there are many approaches for forecasting NIS but all nonemore » of these are based on single models that can be sensitive to time of day and day of week effects.« less

  8. Open Scenario Study, Phase II Report: Assessment and Development of Approaches for Satisfying Unclassified Scenario Needs

    DTIC Science & Technology

    2010-01-01

    interface, another providing the application logic (a program used to manipulate the data), and a server running Microsoft SQL Server or Oracle RDBMS... Oracle ) • Mysql (Open Source) • Other What application server software will be needed? • Application Server • CGI PHP/Perl (Open Source...are used throughout DoD and serve a variety of functions. While DoD has a codified and institutionalized process for the development of a common set

  9. Querying and Computing with BioCyc Databases

    PubMed Central

    Krummenacker, Markus; Paley, Suzanne; Mueller, Lukas; Yan, Thomas; Karp, Peter D.

    2006-01-01

    Summary We describe multiple methods for accessing and querying the complex and integrated cellular data in the BioCyc family of databases: access through multiple file formats, access through Application Program Interfaces (APIs) for LISP, Perl and Java, and SQL access through the BioWarehouse relational database. Availability The Pathway Tools software and 20 BioCyc DBs in Tiers 1 and 2 are freely available to academic users; fees apply to some types of commercial use. For download instructions see http://BioCyc.org/download.shtml PMID:15961440

  10. An Airlift Hub-and-Spoke Location-Routing Model with Time Windows: Case Study of the CONUS-to-Korea Airlift Problem

    DTIC Science & Technology

    1998-03-01

    a point of embarkation to a point of debarkation. This study develops an alternative hub-and-spoke combined location-routing integer linear...programming prototype model, and uses this model to determine what advantages a hub-and-spoke system offers, and in which scenarios it is better-suited than the...extension on the following works: the hierarchical model of Perl and Daskin (1983), time windows features of Chan (1991), combining subtour-breaking and range

  11. Study of different thermal processes on boron-doped PERL cells

    NASA Astrophysics Data System (ADS)

    Li, Wenjia; Wang, Zhenjiao; Han, Peiyu; Lu, Hongyan; Yang, Jian; Guo, Ying; Shi, Zhengrong; Li, Guohua

    2014-08-01

    In this paper, three kinds of thermal processes for boron-doped PERL cells were investigated. These are the forming gas annealing (FGA), the rapid thermal (RTP) and the low temperature annealing processes. FGA was introduced after laser ablation and doping in order to increase minority carrier lifetime by hydrogenating the trapping centers. Subsequent evaluation revealed considerable enhancement of minority carrier lifetime (from 150 μs to 240 μs) and the implied Voc (from 660 mV to 675 mV). After aluminum sputtering, three actual peak temperatures (370 °C, 600 °C and 810 °C) of RTP (as it occurs in the compressed air environment used in our experiment) were utilized to form a contact between the metal and the semi-conductor. It is concluded that only low temperature (lower than 600 °C) firing could create boron back surface field and high quality rear reflector. Lastly, a method of improving the performance of finished PERL cells which did not experience high temperature (over 800 °C) firing was investigated. Finished cells undergone low temperature annealing in N2 atmosphere at 150 °C for 15 min produced 0.44% absolute increase in PERL cells. The enhancement of low temperature annealing originally comes from the activation of passivated boron which is deactivated during FGA.

  12. SEM (Symmetry Equivalent Molecules): a web-based GUI to generate and visualize the macromolecules

    PubMed Central

    Hussain, A. S. Z.; Kumar, Ch. Kiran; Rajesh, C. K.; Sheik, S. S.; Sekar, K.

    2003-01-01

    SEM, Symmetry Equivalent Molecules, is a web-based graphical user interface to generate and visualize the symmetry equivalent molecules (proteins and nucleic acids). In addition, the program allows the users to save the three-dimensional atomic coordinates of the symmetry equivalent molecules in the local machine. The widely recognized graphics program RasMol has been deployed to visualize the reference (input atomic coordinates) and the symmetry equivalent molecules. This program is written using CGI/Perl scripts and has been interfaced with all the three-dimensional structures (solved using X-ray crystallography) available in the Protein Data Bank. The program, SEM, can be accessed over the World Wide Web interface at http://dicsoft2.physics.iisc.ernet.in/sem/ or http://144.16.71.11/sem/. PMID:12824326

  13. BioSmalltalk: a pure object system and library for bioinformatics.

    PubMed

    Morales, Hernán F; Giovambattista, Guillermo

    2013-09-15

    We have developed BioSmalltalk, a new environment system for pure object-oriented bioinformatics programming. Adaptive end-user programming systems tend to become more important for discovering biological knowledge, as is demonstrated by the emergence of open-source programming toolkits for bioinformatics in the past years. Our software is intended to bridge the gap between bioscientists and rapid software prototyping while preserving the possibility of scaling to whole-system biology applications. BioSmalltalk performs better in terms of execution time and memory usage than Biopython and BioPerl for some classical situations. BioSmalltalk is cross-platform and freely available (MIT license) through the Google Project Hosting at http://code.google.com/p/biosmalltalk hernan.morales@gmail.com Supplementary data are available at Bioinformatics online.

  14. The Fundamental Issues Study within the British BMD Review

    DTIC Science & Technology

    1998-02-01

    also be considered. Nevertheless, how formidable a challenge is posed by the ascent release of submunitions is acknowledged by Richard Garwin on the...Arguably, the crunch came in February 1987 when Richard Perle, visiting London as US Assistant Secretary for Defense, extolled a strong SDI as the...resignation of Richard Perle. That year was also to see the departure from political office in the Pentagon of four other SDI stalwarts: Frank

  15. Rear surface effects in high efficiency silicon solar cells

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wenham, S.R.; Robinson, S.J.; Dai, X.

    1994-12-31

    Rear surface effects in PERL solar cells can lead not only to degradation in the short circuit current and open circuit voltage, but also fill factor. Three mechanisms capable of changing the effective rear surface recombination velocity with injection level are identified, two associated with oxidized p-type surfaces, and the third with two dimensional effects associated with a rear floating junction. Each of these will degrade the fill factor if the range of junction biases corresponding to the rear surface transition, coincides with the maximum power point. Despite the identified non idealities, PERL cells with rear floating junctions (PERF cells)more » have achieved record open circuit voltages for silicon solar cells, while simultaneously achieving fill factor improvements relative to standard PERL solar cells. Without optimization, a record efficiency of 22% has been demonstrated for a cell with a rear floating junction. The results of both theoretical and experimental studies are provided.« less

  16. PeRL: A circum-Arctic Permafrost Region Pond and Lake database

    USGS Publications Warehouse

    Muster, Sina; Roth, Kurt; Langer, Moritz; Lange, Stephan; Cresto Aleina, Fabio; Bartsch, Annett; Morgenstern, Anne; Grosse, Guido; Jones, Benjamin M.; Sannel, A.B.K.; Sjoberg, Ylva; Gunther, Frank; Andresen, Christian; Veremeeva, Alexandra; Lindgren, Prajna R.; Bouchard, Frédéric; Lara, Mark J.; Fortier, Daniel; Charbonneau, Simon; Virtanen, Tarmo A.; Hugelius, Gustaf; Palmtag, J.; Siewert, Matthias B.; Riley, William J.; Koven, Charles; Boike, Julia

    2017-01-01

    Ponds and lakes are abundant in Arctic permafrost lowlands. They play an important role in Arctic wetland ecosystems by regulating carbon, water, and energy fluxes and providing freshwater habitats. However, ponds, i.e., waterbodies with surface areas smaller than 1. 0 × 104 m2, have not been inventoried on global and regional scales. The Permafrost Region Pond and Lake (PeRL) database presents the results of a circum-Arctic effort to map ponds and lakes from modern (2002–2013) high-resolution aerial and satellite imagery with a resolution of 5 m or better. The database also includes historical imagery from 1948 to 1965 with a resolution of 6 m or better. PeRL includes 69 maps covering a wide range of environmental conditions from tundra to boreal regions and from continuous to discontinuous permafrost zones. Waterbody maps are linked to regional permafrost landscape maps which provide information on permafrost extent, ground ice volume, geology, and lithology. This paper describes waterbody classification and accuracy, and presents statistics of waterbody distribution for each site. Maps of permafrost landscapes in Alaska, Canada, and Russia are used to extrapolate waterbody statistics from the site level to regional landscape units. PeRL presents pond and lake estimates for a total area of 1. 4 × 106 km2 across the Arctic, about 17 % of the Arctic lowland ( <  300 m a.s.l.) land surface area. PeRL waterbodies with sizes of 1. 0 × 106 m2 down to 1. 0 × 102 m2 contributed up to 21 % to the total water fraction. Waterbody density ranged from 1. 0 × 10 to 9. 4 × 101 km−2. Ponds are the dominant waterbody type by number in all landscapes representing 45–99 % of the total waterbody number. The implementation of PeRL size distributions in land surface models will greatly improve the investigation and projection of surface inundation and carbon fluxes in permafrost lowlands. Waterbody maps, study area boundaries, and maps of regional permafrost landscapes including detailed metadata are available at https://doi.pangaea.de/10.1594/PANGAEA.868349.

  17. Automatically visualise and analyse data on pathways using PathVisioRPC from any programming environment.

    PubMed

    Bohler, Anwesha; Eijssen, Lars M T; van Iersel, Martijn P; Leemans, Christ; Willighagen, Egon L; Kutmon, Martina; Jaillard, Magali; Evelo, Chris T

    2015-08-23

    Biological pathways are descriptive diagrams of biological processes widely used for functional analysis of differentially expressed genes or proteins. Primary data analysis, such as quality control, normalisation, and statistical analysis, is often performed in scripting languages like R, Perl, and Python. Subsequent pathway analysis is usually performed using dedicated external applications. Workflows involving manual use of multiple environments are time consuming and error prone. Therefore, tools are needed that enable pathway analysis directly within the same scripting languages used for primary data analyses. Existing tools have limited capability in terms of available pathway content, pathway editing and visualisation options, and export file formats. Consequently, making the full-fledged pathway analysis tool PathVisio available from various scripting languages will benefit researchers. We developed PathVisioRPC, an XMLRPC interface for the pathway analysis software PathVisio. PathVisioRPC enables creating and editing biological pathways, visualising data on pathways, performing pathway statistics, and exporting results in several image formats in multiple programming environments. We demonstrate PathVisioRPC functionalities using examples in Python. Subsequently, we analyse a publicly available NCBI GEO gene expression dataset studying tumour bearing mice treated with cyclophosphamide in R. The R scripts demonstrate how calls to existing R packages for data processing and calls to PathVisioRPC can directly work together. To further support R users, we have created RPathVisio simplifying the use of PathVisioRPC in this environment. We have also created a pathway module for the microarray data analysis portal ArrayAnalysis.org that calls the PathVisioRPC interface to perform pathway analysis. This module allows users to use PathVisio functionality online without having to download and install the software and exemplifies how the PathVisioRPC interface can be used by data analysis pipelines for functional analysis of processed genomics data. PathVisioRPC enables data visualisation and pathway analysis directly from within various analytical environments used for preliminary analyses. It supports the use of existing pathways from WikiPathways or pathways created using the RPC itself. It also enables automation of tasks performed using PathVisio, making it useful to PathVisio users performing repeated visualisation and analysis tasks. PathVisioRPC is freely available for academic and commercial use at http://projects.bigcat.unimaas.nl/pathvisiorpc.

  18. Mutations in the Circadian Gene period Alter Behavioral and Biochemical Responses to Ethanol in Drosophila

    PubMed Central

    Liao, Jennifer; Seggio, Joseph A.; Ahmad, S. Tariq

    2016-01-01

    Clock genes, such as period, which maintain an organism’s circadian rhythm, can have profound effects on metabolic activity, including ethanol metabolism. In turn, ethanol exposure has been shown in Drosophila and mammals to cause disruptions of the circadian rhythm. Previous studies from our labs have shown that larval ethanol exposure disrupted the free-running period and period expression of Drosophila. In addition, a recent study has shown that arrhythmic flies show no tolerance to ethanol exposure. As such, Drosophila period mutants, which have either a shorter than wild-type free-running period (perS) or a longer one (perL), may also exhibit altered responses to ethanol due to their intrinsic circadian differences. In this study, we tested the initial sensitivity and tolerance of ethanol exposure on Canton-S, perS, and perL, and then measured their Alcohol Dehydrogenase (ADH) and body ethanol levels. We showed that perL flies had slower sedation rate, longer recovery from ethanol sedation, and generated higher tolerance for sedation upon repeated ethanol exposure compared to Canton-S wild-type flies. Furthermore, perL flies had lower ADH activity and had a slower ethanol clearance compared to wild-type flies. The findings of this study suggest that period mutations influence ethanol induced behavior and ethanol metabolism in Drosophila and that flies with longer circadian periods are more sensitive to ethanol exposure. PMID:26802726

  19. A De-Novo Genome Analysis Pipeline (DeNoGAP) for large-scale comparative prokaryotic genomics studies.

    PubMed

    Thakur, Shalabh; Guttman, David S

    2016-06-30

    Comparative analysis of whole genome sequence data from closely related prokaryotic species or strains is becoming an increasingly important and accessible approach for addressing both fundamental and applied biological questions. While there are number of excellent tools developed for performing this task, most scale poorly when faced with hundreds of genome sequences, and many require extensive manual curation. We have developed a de-novo genome analysis pipeline (DeNoGAP) for the automated, iterative and high-throughput analysis of data from comparative genomics projects involving hundreds of whole genome sequences. The pipeline is designed to perform reference-assisted and de novo gene prediction, homolog protein family assignment, ortholog prediction, functional annotation, and pan-genome analysis using a range of proven tools and databases. While most existing methods scale quadratically with the number of genomes since they rely on pairwise comparisons among predicted protein sequences, DeNoGAP scales linearly since the homology assignment is based on iteratively refined hidden Markov models. This iterative clustering strategy enables DeNoGAP to handle a very large number of genomes using minimal computational resources. Moreover, the modular structure of the pipeline permits easy updates as new analysis programs become available. DeNoGAP integrates bioinformatics tools and databases for comparative analysis of a large number of genomes. The pipeline offers tools and algorithms for annotation and analysis of completed and draft genome sequences. The pipeline is developed using Perl, BioPerl and SQLite on Ubuntu Linux version 12.04 LTS. Currently, the software package accompanies script for automated installation of necessary external programs on Ubuntu Linux; however, the pipeline should be also compatible with other Linux and Unix systems after necessary external programs are installed. DeNoGAP is freely available at https://sourceforge.net/projects/denogap/ .

  20. Accessing the SEED genome databases via Web services API: tools for programmers.

    PubMed

    Disz, Terry; Akhter, Sajia; Cuevas, Daniel; Olson, Robert; Overbeek, Ross; Vonstein, Veronika; Stevens, Rick; Edwards, Robert A

    2010-06-14

    The SEED integrates many publicly available genome sequences into a single resource. The database contains accurate and up-to-date annotations based on the subsystems concept that leverages clustering between genomes and other clues to accurately and efficiently annotate microbial genomes. The backend is used as the foundation for many genome annotation tools, such as the Rapid Annotation using Subsystems Technology (RAST) server for whole genome annotation, the metagenomics RAST server for random community genome annotations, and the annotation clearinghouse for exchanging annotations from different resources. In addition to a web user interface, the SEED also provides Web services based API for programmatic access to the data in the SEED, allowing the development of third-party tools and mash-ups. The currently exposed Web services encompass over forty different methods for accessing data related to microbial genome annotations. The Web services provide comprehensive access to the database back end, allowing any programmer access to the most consistent and accurate genome annotations available. The Web services are deployed using a platform independent service-oriented approach that allows the user to choose the most suitable programming platform for their application. Example code demonstrate that Web services can be used to access the SEED using common bioinformatics programming languages such as Perl, Python, and Java. We present a novel approach to access the SEED database. Using Web services, a robust API for access to genomics data is provided, without requiring large volume downloads all at once. The API ensures timely access to the most current datasets available, including the new genomes as soon as they come online.

  1. Solar-energy-system-performance evaluation: Perl-Mack Enterprises, Inc. , single-family residence, Denver, Colorado, April 1978-March 1979

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Walker, R.V.

    1979-01-01

    The Perl-Mack Enterprises, Inc. site is a single-family dwelling whose solar heating system is designed to provide approximately 68% of the annual space heating and hot water requirements. The system consists of an array of flat plate collectors using a water-propylene glycol solution, a concrete water storage tank, and an auxiliary gas burner. The system is described, and its performance is analyzed using a system energy balance technique. (LEW)

  2. Initiated Protocol Telephony Feasibility for the US Navy, Embedded Proof-of-Concept

    DTIC Science & Technology

    2011-03-01

    2.1 Generating Certificates Using Open SSL 1. OpenSSL can be used to generate certificates. There are a number of helper scripts written in Perl that...help with the creation and maintenance of the certificate and keys. OpenSSL is available from a number of sites, i.e., slproweb.com. The default...installation is adequate although it may be useful to add the OpenSSL \\bin directory to the system environment variable PATH. Perl is also available

  3. Plato: A localised orbital based density functional theory code

    NASA Astrophysics Data System (ADS)

    Kenny, S. D.; Horsfield, A. P.

    2009-12-01

    The Plato package allows both orthogonal and non-orthogonal tight-binding as well as density functional theory (DFT) calculations to be performed within a single framework. The package also provides extensive tools for analysing the results of simulations as well as a number of tools for creating input files. The code is based upon the ideas first discussed in Sankey and Niklewski (1989) [1] with extensions to allow high-quality DFT calculations to be performed. DFT calculations can utilise either the local density approximation or the generalised gradient approximation. Basis sets from minimal basis through to ones containing multiple radial functions per angular momenta and polarisation functions can be used. Illustrations of how the package has been employed are given along with instructions for its utilisation. Program summaryProgram title: Plato Catalogue identifier: AEFC_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEFC_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 219 974 No. of bytes in distributed program, including test data, etc.: 1 821 493 Distribution format: tar.gz Programming language: C/MPI and PERL Computer: Apple Macintosh, PC, Unix machines Operating system: Unix, Linux and Mac OS X Has the code been vectorised or parallelised?: Yes, up to 256 processors tested RAM: Up to 2 Gbytes per processor Classification: 7.3 External routines: LAPACK, BLAS and optionally ScaLAPACK, BLACS, PBLAS, FFTW Nature of problem: Density functional theory study of electronic structure and total energies of molecules, crystals and surfaces. Solution method: Localised orbital based density functional theory. Restrictions: Tight-binding and density functional theory only, no exact exchange. Unusual features: Both atom centred and uniform meshes available. Can deal with arbitrary angular momenta for orbitals, whilst still retaining Slater-Koster tables for accuracy. Running time: Test cases will run in a few minutes, large calculations may run for several days.

  4. Regional strategy tested in Caribbean.

    PubMed

    1984-01-01

    Barbados, St. Vincent, and St. Lucia have joined forces in the world's 1st regional Contraceptive Social Marketing (CSM) effort -- the Caribbean CSM. The Barbados Family Planning Association (BFPS) is overseeing the operation, which begins selling 2 contraceptive pills and a condom in early February. Costs and start-up times were shaved by adopting brand names and advertising materials from Jamaica's highly successful CSM project. Jamaica's popular "Panther" condom and "Perle" oral contraceptive (OC) are being used by the Caribbean CSM project. Perle's 9-year-old package has been redesigned and the Caribbean CSM project also is selling a 2nd, low-dose version called "Perle-LD." The products are manufactured in the US by Syntex as Noriday and Norminest, respectively. But the regional approach's financial gains also had a debit side, most notably a tripling of bureaucratic procedures. Part of project difficulties stem from differences among the 3 Caribbean countries. While sharing a common cultural heritage, St. Lucians speak a patois dialect in addition to the English prevalent on the other islands. The biggest hurdle was overcoming an economic disparity between Barbados and its less affluent neighbors, St. Vincent and St. Lucia. The CSM project decided to try a 2-tier product pricing strategy. In US currency, prices run $1.75 per cycle for both OCs on Barbados, but $1.26 on St. Vincent and St. Lucia. A Panther 3-pack costs 75 cents on Barbados and 42 cents on the othe 2 islands. The project is being promoted with generic family planning media advertisements. The project also has held physician orientation seminars on each island. The pilot program will be accompanied by retailer training seminars. In addition the project may introduce a spermicidal foaming tablet, once the US Food and Drug Administration approvs a new American-made product. The unique Caribbean CSM project may spread an idea as potent as the family planning message. Its success could transmit the regional concept worldwide, helping small nations to slow the rate of their population growth.

  5. IPython: components for interactive and parallel computing across disciplines. (Invited)

    NASA Astrophysics Data System (ADS)

    Perez, F.; Bussonnier, M.; Frederic, J. D.; Froehle, B. M.; Granger, B. E.; Ivanov, P.; Kluyver, T.; Patterson, E.; Ragan-Kelley, B.; Sailer, Z.

    2013-12-01

    Scientific computing is an inherently exploratory activity that requires constantly cycling between code, data and results, each time adjusting the computations as new insights and questions arise. To support such a workflow, good interactive environments are critical. The IPython project (http://ipython.org) provides a rich architecture for interactive computing with: 1. Terminal-based and graphical interactive consoles. 2. A web-based Notebook system with support for code, text, mathematical expressions, inline plots and other rich media. 3. Easy to use, high performance tools for parallel computing. Despite its roots in Python, the IPython architecture is designed in a language-agnostic way to facilitate interactive computing in any language. This allows users to mix Python with Julia, R, Octave, Ruby, Perl, Bash and more, as well as to develop native clients in other languages that reuse the IPython clients. In this talk, I will show how IPython supports all stages in the lifecycle of a scientific idea: 1. Individual exploration. 2. Collaborative development. 3. Production runs with parallel resources. 4. Publication. 5. Education. In particular, the IPython Notebook provides an environment for "literate computing" with a tight integration of narrative and computation (including parallel computing). These Notebooks are stored in a JSON-based document format that provides an "executable paper": notebooks can be version controlled, exported to HTML or PDF for publication, and used for teaching.

  6. Uric acid lowering to prevent kidney function loss in diabetes: the preventing early renal function loss (PERL) allopurinol study.

    PubMed

    Maahs, David M; Caramori, Luiza; Cherney, David Z I; Galecki, Andrzej T; Gao, Chuanyun; Jalal, Diana; Perkins, Bruce A; Pop-Busui, Rodica; Rossing, Peter; Mauer, Michael; Doria, Alessandro

    2013-08-01

    Diabetic kidney disease causes significant morbidity and mortality among people with type 1 diabetes (T1D). Intensive glucose and blood pressure control have thus far failed to adequately curb this problem and therefore a major need for novel treatment approaches exists. Multiple observations link serum uric acid levels to kidney disease development and progression in diabetes and strongly argue that uric acid lowering should be tested as one such novel intervention. A pilot of such a trial, using allopurinol, is currently being conducted by the Preventing Early Renal Function Loss (PERL) Consortium. Although the PERL trial targets T1D individuals at highest risk of kidney function decline, the use of allopurinol as a renoprotective agent may also be relevant to a larger segment of the population with diabetes. As allopurinol is inexpensive and safe, it could be cost-effective even for relatively low-risk patients, pending the completion of appropriate trials at earlier stages.

  7. 22.7% efficient PERL silicon solar cell module with a textured front surface

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhao, J.; Wang, A.; Campbell, P.

    1997-12-31

    This paper describes a solar cell module efficiency of 22.7% independently measured at Sandia National Laboratories. This is the highest ever confirmed efficiency for a photovoltaic module of this size achieved by cells made from any material. This 778-cm{sup 2} module used 40 large-area double layer antireflection coated PERL (passivated emitter, rear locally-diffused) silicon cells of average efficiency of 23.1%. A textured front module surface considerably improve the module efficiency. Also reported is an independently confirmed efficiency of 23.7% for a 21.6 cm{sup 2} cell of the type used in the module. Using these PERL cells in the 1996 Worldmore » Solar Challenge solar car race from Darwin to Adelaide across Australia, Honda`s Dream and Aisin Seiki`s Aisol III were placed first and third, respectively. Honda also set a new record by reaching Adelaide in four days with an average speed of 90km/h over the 3010 km course.« less

  8. Semantic-JSON: a lightweight web service interface for Semantic Web contents integrating multiple life science databases

    PubMed Central

    Kobayashi, Norio; Ishii, Manabu; Takahashi, Satoshi; Mochizuki, Yoshiki; Matsushima, Akihiro; Toyoda, Tetsuro

    2011-01-01

    Global cloud frameworks for bioinformatics research databases become huge and heterogeneous; solutions face various diametric challenges comprising cross-integration, retrieval, security and openness. To address this, as of March 2011 organizations including RIKEN published 192 mammalian, plant and protein life sciences databases having 8.2 million data records, integrated as Linked Open or Private Data (LOD/LPD) using SciNetS.org, the Scientists' Networking System. The huge quantity of linked data this database integration framework covers is based on the Semantic Web, where researchers collaborate by managing metadata across public and private databases in a secured data space. This outstripped the data query capacity of existing interface tools like SPARQL. Actual research also requires specialized tools for data analysis using raw original data. To solve these challenges, in December 2009 we developed the lightweight Semantic-JSON interface to access each fragment of linked and raw life sciences data securely under the control of programming languages popularly used by bioinformaticians such as Perl and Ruby. Researchers successfully used the interface across 28 million semantic relationships for biological applications including genome design, sequence processing, inference over phenotype databases, full-text search indexing and human-readable contents like ontology and LOD tree viewers. Semantic-JSON services of SciNetS.org are provided at http://semanticjson.org. PMID:21632604

  9. Documenting AUTOGEN and APGEN Model Files

    NASA Technical Reports Server (NTRS)

    Gladden, Roy E.; Khanampompan, Teerapat; Fisher, Forest W.; DelGuericio, Chris c.

    2008-01-01

    A computer program called "autogen hypertext map generator" satisfies a need for documenting and assisting in visualization of, and navigation through, model files used in the AUTOGEN and APGEN software mentioned in the two immediately preceding articles. This program parses autogen script files, autogen model files, PERL scripts, and apgen activity-definition files and produces a hypertext map of the files to aid in the navigation of the model. This program also provides a facility for adding notes and descriptions, beyond what is in the source model represented by the hypertext map. Further, this program provides access to a summary of the model through variable, function, sub routine, activity and resource declarations as well as providing full access to the source model and source code. The use of the tool enables easy access to the declarations and the ability to traverse routines and calls while analyzing the model.

  10. InverPep: A database of invertebrate antimicrobial peptides.

    PubMed

    Gómez, Esteban A; Giraldo, Paula; Orduz, Sergio

    2017-03-01

    The aim of this work was to construct InverPep, a database specialised in experimentally validated antimicrobial peptides (AMPs) from invertebrates. AMP data contained in InverPep were manually curated from other databases and the scientific literature. MySQL was integrated with the development platform Laravel; this framework allows to integrate programming in PHP with HTML and was used to design the InverPep web page's interface. InverPep contains 18 separated fields, including InverPep code, phylum and species source, peptide name, sequence, peptide length, secondary structure, molar mass, charge, isoelectric point, hydrophobicity, Boman index, aliphatic index and percentage of hydrophobic amino acids. CALCAMPI, an algorithm to calculate the physicochemical properties of multiple peptides simultaneously, was programmed in PERL language. To date, InverPep contains 702 experimentally validated AMPs from invertebrate species. All of the peptides contain information associated with their source, physicochemical properties, secondary structure, biological activity and links to external literature. Most AMPs in InverPep have a length between 10 and 50 amino acids, a positive charge, a Boman index between 0 and 2 kcal/mol, and 30-50% hydrophobic amino acids. InverPep includes 33 AMPs not reported in other databases. Besides, CALCAMPI and statistical analysis of InverPep data is presented. The InverPep database is available in English and Spanish. InverPep is a useful database to study invertebrate AMPs and its information could be used for the design of new peptides. The user-friendly interface of InverPep and its information can be freely accessed via a web-based browser at http://ciencias.medellin.unal.edu.co/gruposdeinvestigacion/prospeccionydisenobiomoleculas/InverPep/public/home_en. Copyright © 2016 International Society for Chemotherapy of Infection and Cancer. Published by Elsevier Ltd. All rights reserved.

  11. Processable Data Making in the Remote Server Sent by Android Phone as a GIS Data Collecting Tool

    NASA Astrophysics Data System (ADS)

    Karaagac, Abdullah; Bostancı, Bulent

    2016-04-01

    Mobile technologies are improving and getting cheaper everyday. Not only smart phones are improved much but also new types of mobile applications and sensors come with the smart phone together. Maps and navigation applications one of the most popular types of applications on these types. Most of these applications uses location services including GNSS, Wi Fi, cellular data and beacon services. Although these coordinate precision not very high, it is appropriate for many applications to utilize. Android is a mobile operating system based on Linux Kernel. It is compatible for varies mobile devices like smart phones, tablets, smart TV's, wearable technologies etc. Android has large capability for application development by using the open source libraries and device sensors like gyroscope, GNSS etc. Android Studio is the most popular integrated development environment (IDE) for Android devices, mainly developing by Google. It had been announced on May 16, 2013 at Google I/O conference. Android Studio is built upon Gradle architecture which is written in Java language. SQLite is a relational database operating system which has so common usage for mobile devices. It developed by using C programming library. It is mostly used via embedding into a software or application. It supports many operating systems including Android. Remote servers can be in several forms from high complexity to simplicity. For this project we will use a open source quad core board computer named Raspberry Pi 2. This device includes 900 MHz ARMv7 compatible quad core CPU, VideoCore IV GPU and 1 GB RAM. Although Raspberry Pi 2's main operating system is Raspbian, we use Debian which are both Linux based operating systems. Raspberry is compatible for many programming language, however some languages are optimized for this device. These are Python, Java, C, C++, Ruby, Perl and Squeak Smalltalk. In this paper, a mobile application will be developed to send coordinate and string data to a SQL database embedded to a remote server. The application will run on Android Operating System running mobile phone. The application will get the location information from the GNSS and cellular data. The user will enter the other information individually. These information will send by clicking a button to remote server which runs SQLite. All these informations will be convertible to any type of measure like type of coordinates could be converted from WGS 84 to ITRF.

  12. Atlas - a data warehouse for integrative bioinformatics.

    PubMed

    Shah, Sohrab P; Huang, Yong; Xu, Tao; Yuen, Macaire M S; Ling, John; Ouellette, B F Francis

    2005-02-21

    We present a biological data warehouse called Atlas that locally stores and integrates biological sequences, molecular interactions, homology information, functional annotations of genes, and biological ontologies. The goal of the system is to provide data, as well as a software infrastructure for bioinformatics research and development. The Atlas system is based on relational data models that we developed for each of the source data types. Data stored within these relational models are managed through Structured Query Language (SQL) calls that are implemented in a set of Application Programming Interfaces (APIs). The APIs include three languages: C++, Java, and Perl. The methods in these API libraries are used to construct a set of loader applications, which parse and load the source datasets into the Atlas database, and a set of toolbox applications which facilitate data retrieval. Atlas stores and integrates local instances of GenBank, RefSeq, UniProt, Human Protein Reference Database (HPRD), Biomolecular Interaction Network Database (BIND), Database of Interacting Proteins (DIP), Molecular Interactions Database (MINT), IntAct, NCBI Taxonomy, Gene Ontology (GO), Online Mendelian Inheritance in Man (OMIM), LocusLink, Entrez Gene and HomoloGene. The retrieval APIs and toolbox applications are critical components that offer end-users flexible, easy, integrated access to this data. We present use cases that use Atlas to integrate these sources for genome annotation, inference of molecular interactions across species, and gene-disease associations. The Atlas biological data warehouse serves as data infrastructure for bioinformatics research and development. It forms the backbone of the research activities in our laboratory and facilitates the integration of disparate, heterogeneous biological sources of data enabling new scientific inferences. Atlas achieves integration of diverse data sets at two levels. First, Atlas stores data of similar types using common data models, enforcing the relationships between data types. Second, integration is achieved through a combination of APIs, ontology, and tools. The Atlas software is freely available under the GNU General Public License at: http://bioinformatics.ubc.ca/atlas/

  13. Atlas – a data warehouse for integrative bioinformatics

    PubMed Central

    Shah, Sohrab P; Huang, Yong; Xu, Tao; Yuen, Macaire MS; Ling, John; Ouellette, BF Francis

    2005-01-01

    Background We present a biological data warehouse called Atlas that locally stores and integrates biological sequences, molecular interactions, homology information, functional annotations of genes, and biological ontologies. The goal of the system is to provide data, as well as a software infrastructure for bioinformatics research and development. Description The Atlas system is based on relational data models that we developed for each of the source data types. Data stored within these relational models are managed through Structured Query Language (SQL) calls that are implemented in a set of Application Programming Interfaces (APIs). The APIs include three languages: C++, Java, and Perl. The methods in these API libraries are used to construct a set of loader applications, which parse and load the source datasets into the Atlas database, and a set of toolbox applications which facilitate data retrieval. Atlas stores and integrates local instances of GenBank, RefSeq, UniProt, Human Protein Reference Database (HPRD), Biomolecular Interaction Network Database (BIND), Database of Interacting Proteins (DIP), Molecular Interactions Database (MINT), IntAct, NCBI Taxonomy, Gene Ontology (GO), Online Mendelian Inheritance in Man (OMIM), LocusLink, Entrez Gene and HomoloGene. The retrieval APIs and toolbox applications are critical components that offer end-users flexible, easy, integrated access to this data. We present use cases that use Atlas to integrate these sources for genome annotation, inference of molecular interactions across species, and gene-disease associations. Conclusion The Atlas biological data warehouse serves as data infrastructure for bioinformatics research and development. It forms the backbone of the research activities in our laboratory and facilitates the integration of disparate, heterogeneous biological sources of data enabling new scientific inferences. Atlas achieves integration of diverse data sets at two levels. First, Atlas stores data of similar types using common data models, enforcing the relationships between data types. Second, integration is achieved through a combination of APIs, ontology, and tools. The Atlas software is freely available under the GNU General Public License at: PMID:15723693

  14. Integrating medical imaging analyses through a high-throughput bundled resource imaging system

    NASA Astrophysics Data System (ADS)

    Covington, Kelsie; Welch, E. Brian; Jeong, Ha-Kyu; Landman, Bennett A.

    2011-03-01

    Exploitation of advanced, PACS-centric image analysis and interpretation pipelines provides well-developed storage, retrieval, and archival capabilities along with state-of-the-art data providence, visualization, and clinical collaboration technologies. However, pursuit of integrated medical imaging analysis through a PACS environment can be limiting in terms of the overhead required to validate, evaluate and integrate emerging research technologies. Herein, we address this challenge through presentation of a high-throughput bundled resource imaging system (HUBRIS) as an extension to the Philips Research Imaging Development Environment (PRIDE). HUBRIS enables PACS-connected medical imaging equipment to invoke tools provided by the Java Imaging Science Toolkit (JIST) so that a medical imaging platform (e.g., a magnetic resonance imaging scanner) can pass images and parameters to a server, which communicates with a grid computing facility to invoke the selected algorithms. Generated images are passed back to the server and subsequently to the imaging platform from which the images can be sent to a PACS. JIST makes use of an open application program interface layer so that research technologies can be implemented in any language capable of communicating through a system shell environment (e.g., Matlab, Java, C/C++, Perl, LISP, etc.). As demonstrated in this proof-of-concept approach, HUBRIS enables evaluation and analysis of emerging technologies within well-developed PACS systems with minimal adaptation of research software, which simplifies evaluation of new technologies in clinical research and provides a more convenient use of PACS technology by imaging scientists.

  15. Security Data Warehouse Application

    NASA Technical Reports Server (NTRS)

    Vernon, Lynn R.; Hennan, Robert; Ortiz, Chris; Gonzalez, Steve; Roane, John

    2012-01-01

    The Security Data Warehouse (SDW) is used to aggregate and correlate all JSC IT security data. This includes IT asset inventory such as operating systems and patch levels, users, user logins, remote access dial-in and VPN, and vulnerability tracking and reporting. The correlation of this data allows for an integrated understanding of current security issues and systems by providing this data in a format that associates it to an individual host. The cornerstone of the SDW is its unique host-mapping algorithm that has undergone extensive field tests, and provides a high degree of accuracy. The algorithm comprises two parts. The first part employs fuzzy logic to derive a best-guess host assignment using incomplete sensor data. The second part is logic to identify and correct errors in the database, based on subsequent, more complete data. Host records are automatically split or merged, as appropriate. The process had to be refined and thoroughly tested before the SDW deployment was feasible. Complexity was increased by adding the dimension of time. The SDW correlates all data with its relationship to time. This lends support to forensic investigations, audits, and overall situational awareness. Another important feature of the SDW architecture is that all of the underlying complexities of the data model and host-mapping algorithm are encapsulated in an easy-to-use and understandable Perl language Application Programming Interface (API). This allows the SDW to be quickly augmented with additional sensors using minimal coding and testing. It also supports rapid generation of ad hoc reports and integration with other information systems.

  16. Yaxx: Yet another X-ray extractor

    NASA Astrophysics Data System (ADS)

    Aldcroft, Tom

    2013-06-01

    Yaxx is a Perl script that facilitates batch data processing using Perl open source software and commonly available software such as CIAO/Sherpa, S-lang, SAS, and FTOOLS. For Chandra and XMM analysis it includes automated spectral extraction, fitting, and report generation. Yaxx can be run without climbing an extensive learning curve; even so, yaxx is highly configurable and can be customized to support complex analysis. yaxx uses template files and takes full advantage of the unique Sherpa / S-lang environment to make much of the processing user configurable. Although originally developed with an emphasis on X-ray data analysis, yaxx evolved to be a general-purpose pipeline scripting package.

  17. JEnsembl: a version-aware Java API to Ensembl data systems.

    PubMed

    Paterson, Trevor; Law, Andy

    2012-11-01

    The Ensembl Project provides release-specific Perl APIs for efficient high-level programmatic access to data stored in various Ensembl database schema. Although Perl scripts are perfectly suited for processing large volumes of text-based data, Perl is not ideal for developing large-scale software applications nor embedding in graphical interfaces. The provision of a novel Java API would facilitate type-safe, modular, object-orientated development of new Bioinformatics tools with which to access, analyse and visualize Ensembl data. The JEnsembl API implementation provides basic data retrieval and manipulation functionality from the Core, Compara and Variation databases for all species in Ensembl and EnsemblGenomes and is a platform for the development of a richer API to Ensembl datasources. The JEnsembl architecture uses a text-based configuration module to provide evolving, versioned mappings from database schema to code objects. A single installation of the JEnsembl API can therefore simultaneously and transparently connect to current and previous database instances (such as those in the public archive) thus facilitating better analysis repeatability and allowing 'through time' comparative analyses to be performed. Project development, released code libraries, Maven repository and documentation are hosted at SourceForge (http://jensembl.sourceforge.net).

  18. SSRscanner: a program for reporting distribution and exact location of simple sequence repeats.

    PubMed

    Anwar, Tamanna; Khan, Asad U

    2006-02-20

    Simple sequence repeats (SSRs) have become important molecular markers for a broad range of applications, such as genome mapping and characterization, phenotype mapping, marker assisted selection of crop plants and a range of molecular ecology and diversity studies. These repeated DNA sequences are found in both prokaryotes and eukaryotes. They are distributed almost at random throughout the genome, ranging from mononucleotide to trinucleotide repeats. They are also found at longer lengths (> 6 repeating units) of tracts. Most of the computer programs that find SSRs do not report its exact position. A computer program SSRscanner was written to find out distribution, frequency and exact location of each SSR in the genome. SSRscanner is user friendly. It can search repeats of any length and produce outputs with their exact position on chromosome and their frequency of occurrence in the sequence. This program has been written in PERL and is freely available for non-commercial users by request from the authors. Please contact the authors by E-mail: huzzi99@hotmail.com.

  19. Production Management System for AMS Computing Centres

    NASA Astrophysics Data System (ADS)

    Choutko, V.; Demakov, O.; Egorov, A.; Eline, A.; Shan, B. S.; Shi, R.

    2017-10-01

    The Alpha Magnetic Spectrometer [1] (AMS) has collected over 95 billion cosmic ray events since it was installed on the International Space Station (ISS) on May 19, 2011. To cope with enormous flux of events, AMS uses 12 computing centers in Europe, Asia and North America, which have different hardware and software configurations. The centers are participating in data reconstruction, Monte-Carlo (MC) simulation [2]/Data and MC production/as well as in physics analysis. Data production management system has been developed to facilitate data and MC production tasks in AMS computing centers, including job acquiring, submitting, monitoring, transferring, and accounting. It was designed to be modularized, light-weighted, and easy-to-be-deployed. The system is based on Deterministic Finite Automaton [3] model, and implemented by script languages, Python and Perl, and the built-in sqlite3 database on Linux operating systems. Different batch management systems, file system storage, and transferring protocols are supported. The details of the integration with Open Science Grid are presented as well.

  20. Wing Classification in the Virtual Research Center

    NASA Technical Reports Server (NTRS)

    Campbell, William H.

    1999-01-01

    The Virtual Research Center (VRC) is a Web site that hosts a database of documents organized to allow teams of scientists and engineers to store and maintain documents. A number of other workgroup-related capabilities are provided. My tasks as a NASA/ASEE Summer Faculty Fellow included developing a scheme for classifying the workgroups using the VRC using the various Divisions within NASA Enterprises. To this end I developed a plan to use several CGI Perl scripts to gather classification information from the leaders of the workgroups, and to display all the workgroups within a specified classification. I designed, implemented, and partially tested scripts which can be used to do the classification. I was also asked to consider directions for future development of the VRC. I think that the VRC can use XML to advantage. XML is a markup language with designer tags that can be used to build meaning into documents. An investigation as to how CORBA, an object-oriented object request broker included with JDK 1.2, might be used also seems justified.

  1. Development of a Google-based search engine for data mining radiology reports.

    PubMed

    Erinjeri, Joseph P; Picus, Daniel; Prior, Fred W; Rubin, David A; Koppel, Paul

    2009-08-01

    The aim of this study is to develop a secure, Google-based data-mining tool for radiology reports using free and open source technologies and to explore its use within an academic radiology department. A Health Insurance Portability and Accountability Act (HIPAA)-compliant data repository, search engine and user interface were created to facilitate treatment, operations, and reviews preparatory to research. The Institutional Review Board waived review of the project, and informed consent was not required. Comprising 7.9 GB of disk space, 2.9 million text reports were downloaded from our radiology information system to a fileserver. Extensible markup language (XML) representations of the reports were indexed using Google Desktop Enterprise search engine software. A hypertext markup language (HTML) form allowed users to submit queries to Google Desktop, and Google's XML response was interpreted by a practical extraction and report language (PERL) script, presenting ranked results in a web browser window. The query, reason for search, results, and documents visited were logged to maintain HIPAA compliance. Indexing averaged approximately 25,000 reports per hour. Keyword search of a common term like "pneumothorax" yielded the first ten most relevant results of 705,550 total results in 1.36 s. Keyword search of a rare term like "hemangioendothelioma" yielded the first ten most relevant results of 167 total results in 0.23 s; retrieval of all 167 results took 0.26 s. Data mining tools for radiology reports will improve the productivity of academic radiologists in clinical, educational, research, and administrative tasks. By leveraging existing knowledge of Google's interface, radiologists can quickly perform useful searches.

  2. Pastoral Group Counselling at a High Security Prison in Israel: Integrating Pierre Janet's Psychological Analysis with Fritz Perls' Gestalt Therapy.

    PubMed

    Brown, Paul; Brown, Marta

    2015-03-01

    This is a report of a short-term, pastoral counselling group conducted with Jewish internees in a high security prison in Israel. It was held as an adjunct to daily secular individual and group counselling and rehabilitation run by the Department of Social Work. Pastoral counselling employed spiritual and psychosocial methodologies to reduce anger, improve prisoner frustration tolerance, and develop a sense of self-efficacy and communal identity. It combined semi-didactic scriptural input with Pierre Janet's personality model, Fritz Perls' gestalt therapy, and analysis of the group process. © The Author(s) 2015 Reprints and permissions:sagepub.co.uk/journalsPermissions.nav.

  3. A Ruby API to query the Ensembl database for genomic features.

    PubMed

    Strozzi, Francesco; Aerts, Jan

    2011-04-01

    The Ensembl database makes genomic features available via its Genome Browser. It is also possible to access the underlying data through a Perl API for advanced querying. We have developed a full-featured Ruby API to the Ensembl databases, providing the same functionality as the Perl interface with additional features. A single Ruby API is used to access different releases of the Ensembl databases and is also able to query multi-species databases. Most functionality of the API is provided using the ActiveRecord pattern. The library depends on introspection to make it release independent. The API is available through the Rubygem system and can be installed with the command gem install ruby-ensembl-api.

  4. OOSTethys - Open Source Software for the Global Earth Observing Systems of Systems

    NASA Astrophysics Data System (ADS)

    Bridger, E.; Bermudez, L. E.; Maskey, M.; Rueda, C.; Babin, B. L.; Blair, R.

    2009-12-01

    An open source software project is much more than just picking the right license, hosting modular code and providing effective documentation. Success in advancing in an open collaborative way requires that the process match the expected code functionality to the developer's personal expertise and organizational needs as well as having an enthusiastic and responsive core lead group. We will present the lessons learned fromOOSTethys , which is a community of software developers and marine scientists who develop open source tools, in multiple languages, to integrate ocean observing systems into an Integrated Ocean Observing System (IOOS). OOSTethys' goal is to dramatically reduce the time it takes to install, adopt and update standards-compliant web services. OOSTethys has developed servers, clients and a registry. Open source PERL, PYTHON, JAVA and ASP tool kits and reference implementations are helping the marine community publish near real-time observation data in interoperable standard formats. In some cases publishing an OpenGeospatial Consortium (OGC), Sensor Observation Service (SOS) from NetCDF files or a database or even CSV text files could take only minutes depending on the skills of the developer. OOSTethys is also developing an OGC standard registry, Catalog Service for Web (CSW). This open source CSW registry was implemented to easily register and discover SOSs using ISO 19139 service metadata. A web interface layer over the CSW registry simplifies the registration process by harvesting metadata describing the observations and sensors from the “GetCapabilities” response of SOS. OPENIOOS is the web client, developed in PERL to visualize the sensors in the SOS services. While the number of OOSTethys software developers is small, currently about 10 around the world, the number of OOSTethys toolkit implementers is larger and growing and the ease of use has played a large role in spreading the use of interoperable standards compliant web services widely in the marine community.

  5. JEnsembl: a version-aware Java API to Ensembl data systems

    PubMed Central

    Paterson, Trevor; Law, Andy

    2012-01-01

    Motivation: The Ensembl Project provides release-specific Perl APIs for efficient high-level programmatic access to data stored in various Ensembl database schema. Although Perl scripts are perfectly suited for processing large volumes of text-based data, Perl is not ideal for developing large-scale software applications nor embedding in graphical interfaces. The provision of a novel Java API would facilitate type-safe, modular, object-orientated development of new Bioinformatics tools with which to access, analyse and visualize Ensembl data. Results: The JEnsembl API implementation provides basic data retrieval and manipulation functionality from the Core, Compara and Variation databases for all species in Ensembl and EnsemblGenomes and is a platform for the development of a richer API to Ensembl datasources. The JEnsembl architecture uses a text-based configuration module to provide evolving, versioned mappings from database schema to code objects. A single installation of the JEnsembl API can therefore simultaneously and transparently connect to current and previous database instances (such as those in the public archive) thus facilitating better analysis repeatability and allowing ‘through time’ comparative analyses to be performed. Availability: Project development, released code libraries, Maven repository and documentation are hosted at SourceForge (http://jensembl.sourceforge.net). Contact: jensembl-develop@lists.sf.net, andy.law@roslin.ed.ac.uk, trevor.paterson@roslin.ed.ac.uk PMID:22945789

  6. Limiting loss mechanisms in 23% efficient silicon solar cells

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aberle, A.G.; Altermatt, P.P.; Heiser, G.

    1995-04-01

    The ``passivated emitter and rear locally diffused`` (PERL) silicon solar cell structure presently demonstrates the highest terrestrial performance of any silicon-based solar cell. This paper presents a detailed investigation of the limiting loss mechanisms in PERL cells exhibiting independently confirmed 1-sun efficiencies of up to 23.0%. Optical, resistive, and recombinative losses are all analyzed under the full range of solar cell operating conditions with the aid of two-dimensional (2D) device simulations. The analysis is based on measurements of the reflectance, quantum efficiency, dark and illuminated current--voltage ({ital I}--{ital V}) characteristics, and properties of the Si--SiO{sub 2} interfaces employed on thesemore » cells for surface passivation. Through the use of the 2D simulations, particular attention has been paid to the magnitudes of the spatially resolved recombination losses in these cells. It is shown that approximately 50% of the recombination losses at the 1-sun maximum power point occur in the base of the cells, followed by recombination losses at the rear and front oxidized surfaces (25% and {lt}25%, respectively). The relatively low fill factors of PERL cells are principally a result of resistive losses; however, the recombination behavior in the base and at the rear surface also contributes. This work predicts that the efficiency of 23% PERL cells could be increased by about 0.7% absolute if ohmic losses were eliminated, a further 1.1% absolute if there were no reflection losses at the nonmetallized front surface regions, about 2.0% by introducing ideal light trapping and eliminating shading losses due to the front metallization, and by about 3.7% absolute if the device had no defect-related recombination losses. New design rules for future efficiency improvements, evident from this analysis, are also presented. {copyright} {ital 1995} {ital American} {ital Institute} {ital of} {ital Physics}.« less

  7. coNCePTual

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pakin, Scott

    2004-05-13

    A frequently reinvented wheel among network researchers is a suite of programs that test a network’s performance. A problem with having umpteen versions of performance tests is that it leads to a variety in the way results are reported; colloquially, apples are often compared to oranges. Consider a bandwidth test. Does a bandwidth test run for a fixed number of iterations or a fixed length of time? Is bandwidth measured as ping-pong bandwidth (i.e., 2 * message length / round-trip time) or unidirectional throughput (N messages in one direction followed by a single acknowledgement message)? Is the acknowledgement message ofmore » minimal length or as long as the entire message? Does its length contribute to the total bandwidth? Is data sent unidirectionally or in both directions at once? How many warmup messages (if any) are sent before the timing loop? Is there a delay after the warmup messages (to give the network a chance to reclaim any scarce resources)? Are receives nonblocking (possibly allowing overlap in the NIC) or blocking? The motivation behind creating coNCePTuaL, a simple specification language designed for describing network benchmarks, is that it enables a benchmark to be described sufficiently tersely as to fit easily in a report or research paper, facilitating peer review of the experimental setup and timing measurements. Because coNCePTuaL code is simple to write, network tests can be developed and deployed with low turnaround times -- useful when the results of one test suggest a following test that should be written. Because coNCePTuaL is special-purpose its run-time system can perform the following functions, which benchmark writers often neglect to implement: * logging information about the environment under which the benchmark ran: operating system, CPU architecture and clock speed, timer type and resolution, etc. * aborting a program if it takes longer than a predetermined length of time to complete * writing measurement data and descriptive statistics to a variety of output formats, including the input formats of various graph-plotting programs coNCePTuaL is not limited to network peformance tests, however. It can also be used for network verification. That is, coNCePTuaL programs can be used to locate failed links or to determine the frequency of bit errors --even those that may sneak past the networks CRC hardware. In addition, because coNCePTuaL is a very high-level language, the coNCePTuaL compiler’s backend has a great deal of potential. It would be possible for the backend to produce a variety of target formats such as Fortran + MPI, Perl + sockets, C + a network vendor’s low-level messaging layer, and so forth. It could directly manipulate a network simulator. It could feed into a graphics program to produce a space-time diagram of a coNCePTuaL program. The possibilities are endless.« less

  8. Runwien: a text-based interface for the WIEN package

    NASA Astrophysics Data System (ADS)

    Otero de la Roza, A.; Luaña, Víctor

    2009-05-01

    A new text-based interface for WIEN2k, the full-potential linearized augmented plane-waves (FPLAPW) program, is presented. This code provides an easy to use, yet powerful way of generating arbitrarily large sets of calculations. Thus, properties over a potential energy surface and WIEN2k parameter exploration can be calculated using a simple input text file. This interface also provides new capabilities to the WIEN2k package, such as the calculation of elastic constants on hexagonal systems or the automatic gathering of relevant information. Additionally, runwien is modular, flexible and intuitive. Program summaryProgram title: runwien Catalogue identifier: AECM_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AECM_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: GPL version 3 No. of lines in distributed program, including test data, etc.: 62 567 No. of bytes in distributed program, including test data, etc.: 610 973 Distribution format: tar.gz Programming language: gawk (with locale POSIX or similar) Computer: All running Unix, Linux Operating system: Unix, GNU/Linux Classification: 7.3 External routines: WIEN2k ( http://www.wien2k.at/), GAWK ( http://www.gnu.org/software/gawk/), rename by L. Wall, a Perl script which renames files, modified by R. Barker to check for the existence of target files, gnuplot ( http://www.gnuplot.info/) Subprograms used:Cat Id: ADSY_v1_0/AECB_v1_0, Title: GIBBS/CRITIC, Reference: CPC 158 (2004) 57/CPC 999 (2009) 999 Nature of problem: Creation of a text-based, batch-oriented interface for the WIEN2k package. Solution method: WIEN2k solves the Kohn-Sham equations of a solid using the FPLAPW formalism. Runwien interprets an input file containing the description of the geometry and structure of the solid and drives the execution of the WIEN2k programs. The input is simplified thanks to the default values of the WIEN2k parameters known to runwien. Additional comments: Designed for WIEN2k versions 06.4, 07.2, 08.2, and 08.3. Running time: For the test case (TiC), a single geometry takes 5 to 10 minutes on a typical desktop PC (Intel Pentium 4, 3.4 GHz, 1 GB RAM). The full example including the calculation of the elastic constants and the equation of state, takes 9 hours and 32 minutes.

  9. Simple sequence repeat marker loci discovery using SSR primer.

    PubMed

    Robinson, Andrew J; Love, Christopher G; Batley, Jacqueline; Barker, Gary; Edwards, David

    2004-06-12

    Simple sequence repeats (SSRs) have become important molecular markers for a broad range of applications, such as genome mapping and characterization, phenotype mapping, marker assisted selection of crop plants and a range of molecular ecology and diversity studies. With the increase in the availability of DNA sequence information, an automated process to identify and design PCR primers for amplification of SSR loci would be a useful tool in plant breeding programs. We report an application that integrates SPUTNIK, an SSR repeat finder, with Primer3, a PCR primer design program, into one pipeline tool, SSR Primer. On submission of multiple FASTA formatted sequences, the script screens each sequence for SSRs using SPUTNIK. The results are parsed to Primer3 for locus-specific primer design. The script makes use of a Web-based interface, enabling remote use. This program has been written in PERL and is freely available for non-commercial users by request from the authors. The Web-based version may be accessed at http://hornbill.cspp.latrobe.edu.au/

  10. Monitoring of International Space Station Telemetry Using Shewhart Control Charts

    NASA Technical Reports Server (NTRS)

    Fitch, Jeffery T.; Simon, Alan L.; Gouveia, John A.; Hillin, Andrew M.; Hernandez, Steve A.

    2012-01-01

    Shewhart control charts have been established as an expedient method for analyzing dynamic, trending data in order to identify anomalous subsystem performance as soon as such performance would exceed a statistically established baseline. Additionally, this leading indicator tool integrates a selection methodology that reduces false positive indications, optimizes true leading indicator events, minimizes computer processor unit duty cycles, and addresses human factor concerns (i.e., the potential for flight-controller data overload). This innovation leverages statistical process control, and provides a relatively simple way to allow flight controllers to focus their attention on subtle system changes that could lead to dramatic off-nominal system performance. Finally, this capability improves response time to potential hardware damage and/or crew injury, thereby improving space flight safety. Shewhart control charts require normalized data. However, the telemetry from the ISS Early External Thermal Control System (EETCS) was not normally distributed. A method for normalizing the data was implemented, as was a means of selecting data windows, the number of standard deviations (Sigma Level), the number of consecutive points out of limits (Sequence), and direction (increasing or decreasing trend data). By varying these options, and treating them like dial settings, the number of nuisance alerts and leading indicators were optimized. The goal was to capture all leading indicators while minimizing the number of nuisances. Lean Six Sigma (L6S) design of experiment methodologies were employed. To optimize the results, Perl programming language was used to automate the massive amounts of telemetry data, control chart plots, and the data analysis.

  11. Speech-rhythm characteristics of client-centered, Gestalt, and rational-emotive therapy interviews.

    PubMed

    Chen, C L

    1981-07-01

    The aim of this study was to discover whether client-centered, Gestalt, and rational-emotive psychotherapy interviews could be described and differentiated on the basis of quantitative measurement of their speech rhythms. These measures were taken from the sound portion of a film showing interviews by Carl Rogers, Frederick Perls, and Albert Ellis. The variables used were total session and percentage of speaking times, speaking turns, vocalizations, interruptions, inside and switching pauses, and speaking rates. The three types of interview had very distinctive patterns of speech-rhythm variables. These patterns suggested that Rogers's Client-centered therapy interview was patient dominated, that Ellis's rational-emotive therapy interview was therapist dominated, and that Perls's Gestalt therapy interview was neither therapist nor patient dominated.

  12. Language-Through-Literature; A Literary Language/Language Arts Program for Bilingual Education, ESL and Other Activities in Early Childhood. Books 1 and 2.

    ERIC Educational Resources Information Center

    King, Paul; King, Eva

    This language-through-literature program is designed to be used as a native language program (language arts/reading readiness), as a second language program, or as a combined native and second language program in early childhood education. Sequentially developed over the year and within each unit, the program is subdivided into 14 units of about…

  13. Awakening the Languages. Challenges of Enduring Language Programs: Field Reports from 15 Programs from Arizona, New Mexico and Oklahoma.

    ERIC Educational Resources Information Center

    Linn, Mary S.; Naranjo, Tessie; Nicholas, Sheilah; Slaughter, Inee; Yamamoto, Akira; Zepeda, Ofelia

    The Indigenous Language Institute (ILI) collaborates with indigenous language communities to combat language decline. ILI facilitates community-based language programs, increases public awareness of language endangerment, and disseminates information on language preservation and successful language revitalization programs. In response to numerous…

  14. SSRscanner: a program for reporting distribution and exact location of simple sequence repeats

    PubMed Central

    Anwar, Tamanna; Khan, Asad U

    2006-01-01

    Simple sequence repeats (SSRs) have become important molecular markers for a broad range of applications, such as genome mapping and characterization, phenotype mapping, marker assisted selection of crop plants and a range of molecular ecology and diversity studies. These repeated DNA sequences are found in both prokaryotes and eukaryotes. They are distributed almost at random throughout the genome, ranging from mononucleotide to trinucleotide repeats. They are also found at longer lengths (> 6 repeating units) of tracts. Most of the computer programs that find SSRs do not report its exact position. A computer program SSRscanner was written to find out distribution, frequency and exact location of each SSR in the genome. SSRscanner is user friendly. It can search repeats of any length and produce outputs with their exact position on chromosome and their frequency of occurrence in the sequence. Availability This program has been written in PERL and is freely available for non-commercial users by request from the authors. Please contact the authors by E-mail: huzzi99@hotmail.com PMID:17597863

  15. Information Metacatalog for a Grid

    NASA Technical Reports Server (NTRS)

    Kolano, Paul

    2007-01-01

    SWIM is a Software Information Metacatalog that gathers detailed information about the software components and packages installed on a grid resource. Information is currently gathered for Executable and Linking Format (ELF) executables and shared libraries, Java classes, shell scripts, and Perl and Python modules. SWIM is built on top of the POUR framework, which is described in the preceding article. SWIM consists of a set of Perl modules for extracting software information from a system, an XML schema defining the format of data that can be added by users, and a POUR XML configuration file that describes how these elements are used to generate periodic, on-demand, and user-specified information. Periodic software information is derived mainly from the package managers used on each system. SWIM collects information from native package managers in FreeBSD, Solaris, and IRX as well as the RPM, Perl, and Python package managers on multiple platforms. Because not all software is available, or installed in package form, SWIM also crawls the set of relevant paths from the File System Hierarchy Standard that defines the standard file system structure used by all major UNIX distributions. Using these two techniques, the vast majority of software installed on a system can be located. SWIM computes the same information gathered by the periodic routines for specific files on specific hosts, and locates software on a system given only its name and type.

  16. UCODE, a computer code for universal inverse modeling

    USGS Publications Warehouse

    Poeter, E.P.; Hill, M.C.

    1999-01-01

    This article presents the US Geological Survey computer program UCODE, which was developed in collaboration with the US Army Corps of Engineers Waterways Experiment Station and the International Ground Water Modeling Center of the Colorado School of Mines. UCODE performs inverse modeling, posed as a parameter-estimation problem, using nonlinear regression. Any application model or set of models can be used; the only requirement is that they have numerical (ASCII or text only) input and output files and that the numbers in these files have sufficient significant digits. Application models can include preprocessors and postprocessors as well as models related to the processes of interest (physical, chemical and so on), making UCODE extremely powerful for model calibration. Estimated parameters can be defined flexibly with user-specified functions. Observations to be matched in the regression can be any quantity for which a simulated equivalent value can be produced, thus simulated equivalent values are calculated using values that appear in the application model output files and can be manipulated with additive and multiplicative functions, if necessary. Prior, or direct, information on estimated parameters also can be included in the regression. The nonlinear regression problem is solved by minimizing a weighted least-squares objective function with respect to the parameter values using a modified Gauss-Newton method. Sensitivities needed for the method are calculated approximately by forward or central differences and problems and solutions related to this approximation are discussed. Statistics are calculated and printed for use in (1) diagnosing inadequate data or identifying parameters that probably cannot be estimated with the available data, (2) evaluating estimated parameter values, (3) evaluating the model representation of the actual processes and (4) quantifying the uncertainty of model simulated values. UCODE is intended for use on any computer operating system: it consists of algorithms programmed in perl, a freeware language designed for text manipulation and Fortran90, which efficiently performs numerical calculations.

  17. An Early-Warning System for Volcanic Ash Dispersal: The MAFALDA Procedure

    NASA Astrophysics Data System (ADS)

    Barsotti, S.; Nannipieri, L.; Neri, A.

    2006-12-01

    Forecasts of the dispersal of volcanic ash is a fundamental goal in order to mitigate its potential impact on urbanized areas and transport routes surrounding explosive volcanoes. To this aim we developed an early- warning procedure named MAFALDA (Modeling And Forecasting Ash Loading and Dispersal in the Atmosphere). Such tool is able to quantitatively forecast the atmospheric concentration of ash as well as the ground deposition as a function of time over a 3D spatial domain.\\The main features of MAFALDA are: (1) the use of the hybrid Lagrangian-Eulerian code VOL-CALPUFF able to describe both the rising column phase and the atmospheric dispersal as a function of weather conditions, (2) the use of high-resolution weather forecasting data, (3) the short execution time that allows to analyse a set of scenarios and (4) the web-based CGI software application (written in Perl programming language) that shows the results in a standard graphical web interface and makes it suitable as an early-warning system during volcanic crises.\\MAFALDA is composed by a computational part that simulates the ash cloud dynamics and a graphical interface for visualizing the modelling results. The computational part includes the codes for elaborating the meteorological data, the dispersal code and the post-processing programs. These produces hourly 2D maps of aerial ash concentration at several vertical levels, extension of "threat" area on air and 2D maps of ash deposit on the ground, in addition to graphs of hourly variations of column height.\\The processed results are available on the web by the graphical interface and the users can choose, by drop-down menu, which data to visualize. \\A first partial application of the procedure has been carried out for Mt. Etna (Italy). In this case, the procedure simulates four volcanological scenarios characterized by different plume intensities and uses 48-hrs weather forecasting data with a resolution of 7 km provided by the Italian Air Force.

  18. The Grid[Way] Job Template Manager, a tool for parameter sweeping

    NASA Astrophysics Data System (ADS)

    Lorca, Alejandro; Huedo, Eduardo; Llorente, Ignacio M.

    2011-04-01

    Parameter sweeping is a widely used algorithmic technique in computational science. It is specially suited for high-throughput computing since the jobs evaluating the parameter space are loosely coupled or independent. A tool that integrates the modeling of a parameter study with the control of jobs in a distributed architecture is presented. The main task is to facilitate the creation and deletion of job templates, which are the elements describing the jobs to be run. Extra functionality relies upon the GridWay Metascheduler, acting as the middleware layer for job submission and control. It supports interesting features like multi-dimensional sweeping space, wildcarding of parameters, functional evaluation of ranges, value-skipping and job template automatic indexation. The use of this tool increases the reliability of the parameter sweep study thanks to the systematic bookkeeping of job templates and respective job statuses. Furthermore, it simplifies the porting of the target application to the grid reducing the required amount of time and effort. Program summaryProgram title: Grid[Way] Job Template Manager (version 1.0) Catalogue identifier: AEIE_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEIE_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Apache license 2.0 No. of lines in distributed program, including test data, etc.: 3545 No. of bytes in distributed program, including test data, etc.: 126 879 Distribution format: tar.gz Programming language: Perl 5.8.5 and above Computer: Any (tested on PC x86 and x86_64) Operating system: Unix, GNU/Linux (tested on Ubuntu 9.04, Scientific Linux 4.7, centOS 5.4), Mac OS X (tested on Snow Leopard 10.6) RAM: 10 MB Classification: 6.5 External routines: The GridWay Metascheduler [1]. Nature of problem: To parameterize and manage an application running on a grid or cluster. Solution method: Generation of job templates as a cross product of the input parameter sets. Also management of the job template files including the job submission to the grid, control and information retrieval. Restrictions: The parameter sweep is limited by disk space during generation of the job templates. The wild-carding of parameters cannot be done in decreasing order. Job submission, control and information is delegated to the GridWay Metascheduler. Running time: From half a second in the simplest operation to a few minutes for thousands of exponential sampling parameters.

  19. MetaPlotR: a Perl/R pipeline for plotting metagenes of nucleotide modifications and other transcriptomic sites.

    PubMed

    Olarerin-George, Anthony O; Jaffrey, Samie R

    2017-05-15

    An increasing number of studies are mapping protein binding and nucleotide modifications sites throughout the transcriptome. Often, these sites cluster in certain regions of the transcript, giving clues to their function. Hence, it is informative to summarize where in the transcript these sites occur. A metagene is a simple and effective tool for visualizing the distribution of sites along a simplified transcript model. In this work, we introduce MetaPlotR, a Perl/R pipeline for creating metagene plots. The code and associated tutorial are available at https://github.com/olarerin/metaPlotR . srj2003@med.cornell.edu. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

  20. Detecting SNPs and estimating allele frequencies in clonal bacterial populations by sequencing pooled DNA.

    PubMed

    Holt, Kathryn E; Teo, Yik Y; Li, Heng; Nair, Satheesh; Dougan, Gordon; Wain, John; Parkhill, Julian

    2009-08-15

    Here, we present a method for estimating the frequencies of SNP alleles present within pooled samples of DNA using high-throughput short-read sequencing. The method was tested on real data from six strains of the highly monomorphic pathogen Salmonella Paratyphi A, sequenced individually and in a pool. A variety of read mapping and quality-weighting procedures were tested to determine the optimal parameters, which afforded > or =80% sensitivity of SNP detection and strong correlation with true SNP frequency at poolwide read depth of 40x, declining only slightly at read depths 20-40x. The method was implemented in Perl and relies on the opensource software Maq for read mapping and SNP calling. The Perl script is freely available from ftp://ftp.sanger.ac.uk/pub/pathogens/pools/.

  1. 25 CFR 39.132 - Can a school integrate Language Development programs into its regular instructional program?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Can a school integrate Language Development programs into... Language Development Programs § 39.132 Can a school integrate Language Development programs into its regular instructional program? A school may offer Language Development programs to students as part of its...

  2. 25 CFR 39.132 - Can a school integrate Language Development programs into its regular instructional program?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Can a school integrate Language Development programs into... Language Development Programs § 39.132 Can a school integrate Language Development programs into its regular instructional program? A school may offer Language Development programs to students as part of its...

  3. A Web-based database for pathology faculty effort reporting.

    PubMed

    Dee, Fred R; Haugen, Thomas H; Wynn, Philip A; Leaven, Timothy C; Kemp, John D; Cohen, Michael B

    2008-04-01

    To ensure appropriate mission-based budgeting and equitable distribution of funds for faculty salaries, our compensation committee developed a pathology-specific effort reporting database. Principles included the following: (1) measurement should be done by web-based databases; (2) most entry should be done by departmental administration or be relational to other databases; (3) data entry categories should be aligned with funding streams; and (4) units of effort should be equal across categories of effort (service, teaching, research). MySQL was used for all data transactions (http://dev.mysql.com/downloads), and scripts were constructed using PERL (http://www.perl.org). Data are accessed with forms that correspond to fields in the database. The committee's work resulted in a novel database using pathology value units (PVUs) as a standard quantitative measure of effort for activities in an academic pathology department. The most common calculation was to estimate the number of hours required for a specific task, divide by 2080 hours (a Medicare year) and then multiply by 100. Other methods included assigning a baseline PVU for program, laboratory, or course directorship with an increment for each student or staff in that unit. With these methods, a faculty member should acquire approximately 100 PVUs. Some outcomes include (1) plotting PVUs versus salary to identify outliers for salary correction, (2) quantifying effort in activities outside the department, (3) documenting salary expenditure for unfunded research, (4) evaluating salary equity by plotting PVUs versus salary by sex, and (5) aggregating data by category of effort for mission-based budgeting and long-term planning.

  4. Calculation of streamflow statistics for Ontario and the Great Lakes states

    USGS Publications Warehouse

    Piggott, Andrew R.; Neff, Brian P.

    2005-01-01

    Basic, flow-duration, and n-day frequency statistics were calculated for 779 current and historical streamflow gages in Ontario and 3,157 streamflow gages in the Great Lakes states with length-of-record daily mean streamflow data ending on December 31, 2000 and September 30, 2001, respectively. The statistics were determined using the U.S. Geological Survey’s SWSTAT and IOWDM, ANNIE, and LIBANNE software and Linux shell and PERL programming that enabled the mass processing of the data and calculation of the statistics. Verification exercises were performed to assess the accuracy of the processing and calculations. The statistics and descriptions, longitudes and latitudes, and drainage areas for each of the streamflow gages are summarized in ASCII text files and ESRI shapefiles.

  5. JLIFE: THE JEFFERSON LAB INTERACTIVE FRONT END FOR THE OPTICAL PROPAGATION CODE

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Watson, Anne M.; Shinn, Michelle D.

    2013-08-01

    We present details on a graphical interface for the open source software program Optical Propagation Code, or OPC. This interface, written in Java, allows a user with no knowledge of OPC to create an optical system, with lenses, mirrors, apertures, etc. and the appropriate drifts between them. The Java code creates the appropriate Perl script that serves as the input for OPC. The mode profile is then output at each optical element. The display can be either an intensity profile along the x axis, or as an isometric 3D plot which can be tilted and rotated. These profiles can bemore » saved. Examples of the input and output will be presented.« less

  6. Three Psychotherapies Examined: Ellis, Rogers, Perls

    ERIC Educational Resources Information Center

    Stoten, J.; Goos, W.

    1974-01-01

    This study uses Bales' Interaction Process Analysis (I. P. A.) to identify significant process elements in counselling and psychotherapy. For this purpose, the film "Three Approaches to Psychotherapy" was analysed. (Editor)

  7. 25 CFR 39.136 - What is the WSU for Language Development programs?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false What is the WSU for Language Development programs? 39.136... EQUALIZATION PROGRAM Indian School Equalization Formula Language Development Programs § 39.136 What is the WSU for Language Development programs? Language Development programs are funded at 0.13 WSUs per student. ...

  8. Assessing Foreign Language Proficiency of Undergraduates. Issues in Language Program Direction: A Series of Annual Volumes.

    ERIC Educational Resources Information Center

    Teschner, Richard V., Ed.

    This collection of papers includes: "Foreign Language Testing Today: Issues in Language Program Direction" (Frank Nuessel); "Assessing the Problems of Assessment" (M. Peter Hagiwara); "Testing in Foreign Language Programs and Testing Programs in Foreign Language Departments: Reflections and Recommendations" (Elizabeth…

  9. 25 CFR 39.131 - What is a Language Development Program?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... EQUALIZATION PROGRAM Indian School Equalization Formula Language Development Programs § 39.131 What is a Language Development Program? A Language Development program is one that serves students who either: (a...

  10. 25 CFR 39.131 - What is a Language Development Program?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... EQUALIZATION PROGRAM Indian School Equalization Formula Language Development Programs § 39.131 What is a Language Development Program? A Language Development program is one that serves students who either: (a...

  11. 25 CFR 39.131 - What is a Language Development Program?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... EQUALIZATION PROGRAM Indian School Equalization Formula Language Development Programs § 39.131 What is a Language Development Program? A Language Development program is one that serves students who either: (a...

  12. Research Issues and Language Program Direction. Issues in Language Program Direction: A Series of Annual Volumes.

    ERIC Educational Resources Information Center

    Heilenman, L. Kathy, Ed.

    This collection of papers is divided into two parts. After "Introduction" (L. Kathy Heilenman), Part 1, "Research and Language Program Directors: The Relationship," includes "Research Domains and Language Program Direction" (Bill VanPatten); "Language Program Direction and the Modernist Agenda" (Celeste…

  13. HPV-QUEST: A highly customized system for automated HPV sequence analysis capable of processing Next Generation sequencing data set.

    PubMed

    Yin, Li; Yao, Jiqiang; Gardner, Brent P; Chang, Kaifen; Yu, Fahong; Goodenow, Maureen M

    2012-01-01

    Next Generation sequencing (NGS) applied to human papilloma viruses (HPV) can provide sensitive methods to investigate the molecular epidemiology of multiple type HPV infection. Currently a genotyping system with a comprehensive collection of updated HPV reference sequences and a capacity to handle NGS data sets is lacking. HPV-QUEST was developed as an automated and rapid HPV genotyping system. The web-based HPV-QUEST subtyping algorithm was developed using HTML, PHP, Perl scripting language, and MYSQL as the database backend. HPV-QUEST includes a database of annotated HPV reference sequences with updated nomenclature covering 5 genuses, 14 species and 150 mucosal and cutaneous types to genotype blasted query sequences. HPV-QUEST processes up to 10 megabases of sequences within 1 to 2 minutes. Results are reported in html, text and excel formats and display e-value, blast score, and local and coverage identities; provide genus, species, type, infection site and risk for the best matched reference HPV sequence; and produce results ready for additional analyses.

  14. ExportAid: database of RNA elements regulating nuclear RNA export in mammals.

    PubMed

    Giulietti, Matteo; Milantoni, Sara Armida; Armeni, Tatiana; Principato, Giovanni; Piva, Francesco

    2015-01-15

    Regulation of nuclear mRNA export or retention is carried out by RNA elements but the mechanism is not yet well understood. To understand the mRNA export process, it is important to collect all the involved RNA elements and their trans-acting factors. By hand-curated literature screening we collected, in ExportAid database, experimentally assessed data about RNA elements regulating nuclear export or retention of endogenous, heterologous or artificial RNAs in mammalian cells. This database could help to understand the RNA export language and to study the possible export efficiency alterations owing to mutations or polymorphisms. Currently, ExportAid stores 235 and 96 RNA elements, respectively, increasing and decreasing export efficiency, and 98 neutral assessed sequences. Freely accessible without registration at http://www.introni.it/ExportAid/ExportAid.html. Database and web interface are implemented in Perl, MySQL, Apache and JavaScript with all major browsers supported. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  15. IVS Working Group 4: VLBI Data Structures

    NASA Astrophysics Data System (ADS)

    Gipson, J.

    2012-12-01

    I present an overview of the "openDB format" for storing, archiving, and processing VLBI data. In this scheme, most VLBI data is stored in NetCDF files. NetCDF has the advantage that there are interfaces to most common computer languages including Fortran, Fortran-90, C, C++, Perl, etc, and the most common operating systems including Linux, Windows, and Mac. The data files for a particular session are organized by special ASCII "wrapper" files which contain pointers to the data files. This allows great flexibility in the processing and analysis of VLBI data. For example it allows you to easily change subsets of the data used in the analysis such as troposphere modeling, ionospheric calibration, editing, and ambiguity resolution. It also allows for extending the types of data used, e.g., source maps. I present a roadmap to transition to this new format. The new format can already be used by VieVS and by the global mode of solve. There are plans in work for other software packages to be able to use the new format.

  16. Extension of the COG and arCOG databases by amino acid and nucleotide sequences

    PubMed Central

    Meereis, Florian; Kaufmann, Michael

    2008-01-01

    Background The current versions of the COG and arCOG databases, both excellent frameworks for studies in comparative and functional genomics, do not contain the nucleotide sequences corresponding to their protein or protein domain entries. Results Using sequence information obtained from GenBank flat files covering the completely sequenced genomes of the COG and arCOG databases, we constructed NUCOCOG (nucleotide sequences containing COG databases) as an extended version including all nucleotide sequences and in addition the amino acid sequences originally utilized to construct the current COG and arCOG databases. We make available three comprehensive single XML files containing the complete databases including all sequence information. In addition, we provide a web interface as a utility suitable to browse the NUCOCOG database for sequence retrieval. The database is accessible at . Conclusion NUCOCOG offers the possibility to analyze any sequence related property in the context of the COG and arCOG framework simply by using script languages such as PERL applied to a large but single XML document. PMID:19014535

  17. A survey of functional programming language principles

    NASA Technical Reports Server (NTRS)

    Holloway, C. M.

    1986-01-01

    Research in the area of functional programming languages has intensified in the 8 years since John Backus' Turing Award Lecture on the topic was published. The purpose of this paper is to present a survey of the ideas of functional programming languages. The paper assumes the reader is comfortable with mathematics and has knowledge of the basic principles of traditional programming languages, but does not assume any prior knowledge of the ideas of functional languages. A simple functional language is defined and used to illustrate the basic ideas. Topics discussed include the reasons for developing functional languages, methods of expressing concurrency, the algebra of functional programming languages, program transformation techniques, and implementations of functional languages. Existing functional languages are also mentioned. The paper concludes with the author's opinions as to the future of functional languages. An annotated bibliography on the subject is also included.

  18. 25 CFR 39.137 - May schools operate a language development program without a specific appropriation from Congress?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false May schools operate a language development program... Formula Language Development Programs § 39.137 May schools operate a language development program without a specific appropriation from Congress? Yes, a school may operate a language development program...

  19. 34 CFR 658.1 - What is the Undergraduate International Studies and Foreign Language Program?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Foreign Language Program? 658.1 Section 658.1 Education Regulations of the Offices of the Department of... STUDIES AND FOREIGN LANGUAGE PROGRAM General § 658.1 What is the Undergraduate International Studies and Foreign Language Program? The Undergraduate International Studies and Foreign Language Program is designed...

  20. 34 CFR 669.1 - What is the Language Resource Centers Program?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What is the Language Resource Centers Program? 669.1... POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION LANGUAGE RESOURCE CENTERS PROGRAM General § 669.1 What is the Language Resource Centers Program? The Language Resource Centers Program makes awards, through grants or...

  1. 34 CFR 658.1 - What is the Undergraduate International Studies and Foreign Language Program?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Foreign Language Program? 658.1 Section 658.1 Education Regulations of the Offices of the Department of... STUDIES AND FOREIGN LANGUAGE PROGRAM General § 658.1 What is the Undergraduate International Studies and Foreign Language Program? The Undergraduate International Studies and Foreign Language Program is designed...

  2. 34 CFR 669.1 - What is the Language Resource Centers Program?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 3 2011-07-01 2011-07-01 false What is the Language Resource Centers Program? 669.1... POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION LANGUAGE RESOURCE CENTERS PROGRAM General § 669.1 What is the Language Resource Centers Program? The Language Resource Centers Program makes awards, through grants or...

  3. Flight program language requirements. Volume 2: Requirements and evaluations

    NASA Technical Reports Server (NTRS)

    1972-01-01

    The efforts and results are summarized for a study to establish requirements for a flight programming language for future onboard computer applications. Several different languages were available as potential candidates for future NASA flight programming efforts. The study centered around an evaluation of the four most pertinent existing aerospace languages. Evaluation criteria were established, and selected kernels from the current Saturn 5 and Skylab flight programs were used as benchmark problems for sample coding. An independent review of the language specifications incorporated anticipated future programming requirements into the evaluation. A set of detailed language requirements was synthesized from these activities. The details of program language requirements and of the language evaluations are described.

  4. Genome Annotation Generator: a simple tool for generating and correcting WGS annotation tables for NCBI submission.

    PubMed

    Geib, Scott M; Hall, Brian; Derego, Theodore; Bremer, Forest T; Cannoles, Kyle; Sim, Sheina B

    2018-04-01

    One of the most overlooked, yet critical, components of a whole genome sequencing (WGS) project is the submission and curation of the data to a genomic repository, most commonly the National Center for Biotechnology Information (NCBI). While large genome centers or genome groups have developed software tools for post-annotation assembly filtering, annotation, and conversion into the NCBI's annotation table format, these tools typically require back-end setup and connection to an Structured Query Language (SQL) database and/or some knowledge of programming (Perl, Python) to implement. With WGS becoming commonplace, genome sequencing projects are moving away from the genome centers and into the ecology or biology lab, where fewer resources are present to support the process of genome assembly curation. To fill this gap, we developed software to assess, filter, and transfer annotation and convert a draft genome assembly and annotation set into the NCBI annotation table (.tbl) format, facilitating submission to the NCBI Genome Assembly database. This software has no dependencies, is compatible across platforms, and utilizes a simple command to perform a variety of simple and complex post-analysis, pre-NCBI submission WGS project tasks. The Genome Annotation Generator is a consistent and user-friendly bioinformatics tool that can be used to generate a .tbl file that is consistent with the NCBI submission pipeline. The Genome Annotation Generator achieves the goal of providing a publicly available tool that will facilitate the submission of annotated genome assemblies to the NCBI. It is useful for any individual researcher or research group that wishes to submit a genome assembly of their study system to the NCBI.

  5. Genome Annotation Generator: a simple tool for generating and correcting WGS annotation tables for NCBI submission

    PubMed Central

    Hall, Brian; Derego, Theodore; Bremer, Forest T; Cannoles, Kyle

    2018-01-01

    Abstract Background One of the most overlooked, yet critical, components of a whole genome sequencing (WGS) project is the submission and curation of the data to a genomic repository, most commonly the National Center for Biotechnology Information (NCBI). While large genome centers or genome groups have developed software tools for post-annotation assembly filtering, annotation, and conversion into the NCBI’s annotation table format, these tools typically require back-end setup and connection to an Structured Query Language (SQL) database and/or some knowledge of programming (Perl, Python) to implement. With WGS becoming commonplace, genome sequencing projects are moving away from the genome centers and into the ecology or biology lab, where fewer resources are present to support the process of genome assembly curation. To fill this gap, we developed software to assess, filter, and transfer annotation and convert a draft genome assembly and annotation set into the NCBI annotation table (.tbl) format, facilitating submission to the NCBI Genome Assembly database. This software has no dependencies, is compatible across platforms, and utilizes a simple command to perform a variety of simple and complex post-analysis, pre-NCBI submission WGS project tasks. Findings The Genome Annotation Generator is a consistent and user-friendly bioinformatics tool that can be used to generate a .tbl file that is consistent with the NCBI submission pipeline Conclusions The Genome Annotation Generator achieves the goal of providing a publicly available tool that will facilitate the submission of annotated genome assemblies to the NCBI. It is useful for any individual researcher or research group that wishes to submit a genome assembly of their study system to the NCBI. PMID:29635297

  6. MOCASSIN-prot software

    USDA-ARS?s Scientific Manuscript database

    MOCASSIN-prot is a software, implemented in Perl and Matlab, for constructing protein similarity networks to classify proteins. Both domain composition and quantitative sequence similarity information are utilized in constructing the directed protein similarity networks. For each reference protein i...

  7. Personal Change and Intervention Style

    ERIC Educational Resources Information Center

    Andrews, John D. W.

    1977-01-01

    Presents a theory of personal change and analyzes growth-producing interventions using examples from the film, "Three Approaches to Psychotherapy". Compares the styles of Carl Rogers, Frttz Perls, and Albert Ellis to illustrate the theory. (Editor/RK)

  8. Learning through an Aboriginal Language: The Impact on Students' English and Aboriginal Language Skills

    ERIC Educational Resources Information Center

    Usborne, Esther; Peck, Josephine; Smith, Donna-Lee; Taylor, Donald M.

    2011-01-01

    Aboriginal communities across Canada are implementing Aboriginal language programs in their schools. In the present research, we explore the impact of learning through an Aboriginal language on students' English and Aboriginal language skills by contrasting a Mi'kmaq language immersion program with a Mi'kmaq as a second language program. The…

  9. A brief description and comparison of programming languages FORTRAN, ALGOL, COBOL, PL/1, and LISP 1.5 from a critical standpoint

    NASA Technical Reports Server (NTRS)

    Mathur, F. P.

    1972-01-01

    Several common higher level program languages are described. FORTRAN, ALGOL, COBOL, PL/1, and LISP 1.5 are summarized and compared. FORTRAN is the most widely used scientific programming language. ALGOL is a more powerful language for scientific programming. COBOL is used for most commercial programming applications. LISP 1.5 is primarily a list-processing language. PL/1 attempts to combine the desirable features of FORTRAN, ALGOL, and COBOL into a single language.

  10. TreSpEx—Detection of Misleading Signal in Phylogenetic Reconstructions Based on Tree Information

    PubMed Central

    Struck, Torsten H

    2014-01-01

    Phylogenies of species or genes are commonplace nowadays in many areas of comparative biological studies. However, for phylogenetic reconstructions one must refer to artificial signals such as paralogy, long-branch attraction, saturation, or conflict between different datasets. These signals might eventually mislead the reconstruction even in phylogenomic studies employing hundreds of genes. Unfortunately, there has been no program allowing the detection of such effects in combination with an implementation into automatic process pipelines. TreSpEx (Tree Space Explorer) now combines different approaches (including statistical tests), which utilize tree-based information like nodal support or patristic distances (PDs) to identify misleading signals. The program enables the parallel analysis of hundreds of trees and/or predefined gene partitions, and being command-line driven, it can be integrated into automatic process pipelines. TreSpEx is implemented in Perl and supported on Linux, Mac OS X, and MS Windows. Source code, binaries, and additional material are freely available at http://www.annelida.de/research/bioinformatics/software.html. PMID:24701118

  11. CommServer: A Communications Manager For Remote Data Sites

    NASA Astrophysics Data System (ADS)

    Irving, K.; Kane, D. L.

    2012-12-01

    CommServer is a software system that manages making connections to remote data-gathering stations, providing a simple network interface to client applications. The client requests a connection to a site by name, and the server establishes the connection, providing a bidirectional channel between the client and the target site if successful. CommServer was developed to manage networks of FreeWave serial data radios with multiple data sites, repeaters, and network-accessed base stations, and has been in continuous operational use for several years. Support for Iridium modems using RUDICS will be added soon, and no changes to the application interface are anticipated. CommServer is implemented on Linux using programs written in bash shell, Python, Perl, AWK, under a set of conventions we refer to as ThinObject.

  12. “PERLE bedside-examination-course for candidates in state examination” – Developing a training program for the third part of medical state examination (oral examination with practical skills)

    PubMed Central

    Karthaus, Anne; Schmidt, Anita

    2016-01-01

    Introduction: In preparation for the state examination, many students have open questions and a need for advice. Tutors of the Skills Lab PERLE-„Praxis ERfahren und Lernen“ (experiencing and learning practical skills) have developed a new course concept to provide support and practical assistance for the examinees. Objectives: The course aims to familiarize the students with the exam situation in order to gain more confidence. This enables the students to experience a confrontation with the specific situation of the exam in a protected environment. Furthermore, soft skills are utilized and trained. Concept of the course: The course was inspired by the OSCE-model (Objective Structured Clinical Examination), an example for case-based learning and controlling. Acquired knowledge can be revised and extended through the case studies. Experienced tutors provide assistance in discipline-specific competencies, and help in organizational issues such as dress code and behaviour. Evaluation of the course: An evaluation was conducted by the attending participants after every course. Based on this assessment, the course is constantly being developed. In March, April and October 2015 six courses, with a total of 84 participants, took place. Overall 76 completed questionnaires (91%) were analysed. Discussion: Strengths of the course are a good tutor-participants-ratio with 1:4 (1 Tutor provides guidance for 4 participants), the interactivity of the course, and the high flexibility in responding to the group's needs. Weaknesses are the tight schedule, and the currently not yet performed evaluation before and after the course. Conclusion: In terms of “best practise”, this article shows an example of how to offer low-cost and low-threshold preparation for the state examination. PMID:27579355

  13. "PERLE bedside-examination-course for candidates in state examination" - Developing a training program for the third part of medical state examination (oral examination with practical skills).

    PubMed

    Karthaus, Anne; Schmidt, Anita

    2016-01-01

    In preparation for the state examination, many students have open questions and a need for advice. Tutors of the Skills Lab PERLE-"Praxis ERfahren und Lernen" (experiencing and learning practical skills) have developed a new course concept to provide support and practical assistance for the examinees. The course aims to familiarize the students with the exam situation in order to gain more confidence. This enables the students to experience a confrontation with the specific situation of the exam in a protected environment. Furthermore, soft skills are utilized and trained. Concept of the course: The course was inspired by the OSCE-model (Objective Structured Clinical Examination), an example for case-based learning and controlling. Acquired knowledge can be revised and extended through the case studies. Experienced tutors provide assistance in discipline-specific competencies, and help in organizational issues such as dress code and behaviour. Evaluation of the course: An evaluation was conducted by the attending participants after every course. Based on this assessment, the course is constantly being developed. In March, April and October 2015 six courses, with a total of 84 participants, took place. Overall 76 completed questionnaires (91%) were analysed. Strengths of the course are a good tutor-participants-ratio with 1:4 (1 Tutor provides guidance for 4 participants), the interactivity of the course, and the high flexibility in responding to the group's needs. Weaknesses are the tight schedule, and the currently not yet performed evaluation before and after the course. In terms of "best practise", this article shows an example of how to offer low-cost and low-threshold preparation for the state examination.

  14. Flight program language requirements. Volume 1: Executive summary

    NASA Technical Reports Server (NTRS)

    1972-01-01

    The activities and results of a study for the definition of flight program language requirements are described. A set of detailed requirements are presented for a language capable of supporting onboard application programming for the Marshall Space Flight Center's anticipated future activities in the decade of 1975-85. These requirements are based, in part, on the evaluation of existing flight programming language designs to determine the applicability of these designs to flight programming activities which are anticipated. The coding of benchmark problems in the selected programming languages is discussed. These benchmarks are in the form of program kernels selected from existing flight programs. This approach was taken to insure that the results of the study would reflect state of the art language capabilities, as well as to determine whether an existing language design should be selected for adaptation.

  15. Person-Centered Gestalt Therapy: A Synthesis.

    ERIC Educational Resources Information Center

    Herlihy, Barbara

    1985-01-01

    Highlights the similarities between the person-centered approach to counseling of Carl Rogers and the Gestalt therapy of Fritz Perls. Discusses implementation of the two approaches and suggests they may be synthesized into a person-centered Gestalt therapy. (MCF)

  16. Gestalt Workshops: Suggested In-Service Training for Teachers.

    ERIC Educational Resources Information Center

    Fiordo, Richard

    1981-01-01

    Fritz Perls' Gestalt Workshops are explained and recommended for inservice training for teachers. Since Gestalt Workshops increase their participants' growth, awareness, and integration personally and environmentally, their benefit to classroom teachers would be direct and dramatic. (Author)

  17. Adding EUNIS and VAULT rocket data to the VSO with Modern Perl frameworks

    NASA Astrophysics Data System (ADS)

    Mansky, Edmund

    2017-08-01

    A new Perl code is described, that uses the modern Object-oriented Moose framework, to add EUNIS and VAULT rocket data to the Virtual Solar Observatory website. The code permits the easy fixing of FITS header fields in the case where some FITS fields that are required are missing from the original data files. The code makes novel use of the Moose extensions “before” and “after” to build in dependencies so that database creation of tables occurs before the loading of data, and that the validation of file-dependent tables occurs after the loading is completed. Also described is the computation and loading of the deferred FITS field CHECKSUM into the database following the loading and validation of the file-dependent tables. The loading of the EUNIS 2006 and 2007 flight data, and the VAULT 2.0 flight data is described in detail as illustrative examples.

  18. Laser doping of boron-doped Si paste for high-efficiency silicon solar cells

    NASA Astrophysics Data System (ADS)

    Tomizawa, Yuka; Imamura, Tetsuya; Soeda, Masaya; Ikeda, Yoshinori; Shiro, Takashi

    2015-08-01

    Boron laser doping (LD) is a promising technology for high-efficiency solar cells such as p-type passivated locally diffused solar cells and n-type Si-wafer-based solar cells. We produced a printable phosphorus- or boron-doped Si paste (NanoGram® Si paste/ink) for use as a diffuser in the LD process. We used the boron LD process to fabricate high-efficiency passivated emitter and rear locally diffused (PERL) solar cells. PERL solar cells on Czochralski Si (Cz-Si) wafers yielded a maximum efficiency of 19.7%, whereas the efficiency of a reference cell was 18.5%. Fill factors above 79% and open circuit voltages above 655 mV were measured. We found that the boron-doped area effectively performs as a local boron back surface field (BSF). The characteristics of the solar cell formed using NanoGram® Si paste/ink were better than those of the reference cell.

  19. A RESTful Service Oriented Architecture for Science Data Processing

    NASA Astrophysics Data System (ADS)

    Duggan, B.; Tilmes, C.; Durbin, P.; Masuoka, E.

    2012-12-01

    The Atmospheric Composition Processing System is an implementation of a RESTful Service Oriented Architecture which handles incoming data from the Ozone Monitoring Instrument and the Ozone Monitoring and Profiler Suite aboard the Aura and NPP spacecrafts respectively. The system has been built entirely from open source components, such as Postgres, Perl, and SQLite and has leveraged the vast resources of the Comprehensive Perl Archive Network (CPAN). The modular design of the system also allows for many of the components to be easily released and integrated into the CPAN ecosystem and reused independently. At minimal expense, the CPAN infrastructure and community provide peer review, feedback and continuous testing in a wide variety of environments and architectures. A well defined set of conventions also facilitates dependency management, packaging, and distribution of code. Test driven development also provides a way to ensure stability despite a continuously changing base of dependencies.

  20. 25 CFR 39.130 - Can ISEF funds be used for Language Development Programs?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... INDIAN SCHOOL EQUALIZATION PROGRAM Indian School Equalization Formula Language Development Programs § 39.130 Can ISEF funds be used for Language Development Programs? Yes, schools can use ISEF funds to... 25 Indians 1 2010-04-01 2010-04-01 false Can ISEF funds be used for Language Development Programs...

  1. 25 CFR 39.130 - Can ISEF funds be used for Language Development Programs?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Can ISEF funds be used for Language Development Programs... INDIAN SCHOOL EQUALIZATION PROGRAM Indian School Equalization Formula Language Development Programs § 39.130 Can ISEF funds be used for Language Development Programs? Yes, schools can use ISEF funds to...

  2. C++ Programming Language

    NASA Technical Reports Server (NTRS)

    Shaykhian, Gholam Ali

    2007-01-01

    C++ Programming Language: The C++ seminar covers the fundamentals of C++ programming language. The C++ fundamentals are grouped into three parts where each part includes both concept and programming examples aimed at for hands-on practice. The first part covers the functional aspect of C++ programming language with emphasis on function parameters and efficient memory utilization. The second part covers the essential framework of C++ programming language, the object-oriented aspects. Information necessary to evaluate various features of object-oriented programming; including encapsulation, polymorphism and inheritance will be discussed. The last part of the seminar covers template and generic programming. Examples include both user defined and standard templates.

  3. The Trajectory of Language Policy: The First Language Maintenance and Development Program in South Australia

    ERIC Educational Resources Information Center

    Liddicoat, Anthony J.; Curnow, Timothy Jowan; Scarino, Angela

    2016-01-01

    This paper examines the development of the First Language Maintenance and Development (FLMD) program in South Australia. This program is the main language policy activity that specifically focuses on language maintenance in government primary schools and has existed since 1986. During this time, the program has evolved largely as the result of ad…

  4. Spanish-language community-based mental health treatment programs, policy-required language-assistance programming, and mental health treatment access among Spanish-speaking clients.

    PubMed

    Snowden, Lonnie R; McClellan, Sean R

    2013-09-01

    We investigated the extent to which implementing language assistance programming through contracting with community-based organizations improved the accessibility of mental health care under Medi-Cal (California's Medicaid program) for Spanish-speaking persons with limited English proficiency, and whether it reduced language-based treatment access disparities. Using a time series nonequivalent control group design, we studied county-level penetration of language assistance programming over 10 years (1997-2006) for Spanish-speaking persons with limited English proficiency covered under Medi-Cal. We used linear regression with county fixed effects to control for ongoing trends and other influences. When county mental health plans contracted with community-based organizations, those implementing language assistance programming increased penetration rates of Spanish-language mental health services under Medi-Cal more than other plans (0.28 percentage points, a 25% increase on average; P < .05). However, the increase was insufficient to significantly reduce language-related disparities. Mental health treatment programs operated by community-based organizations may have moderately improved access after implementing required language assistance programming, but the programming did not reduce entrenched disparities in the accessibility of mental health services.

  5. Spanish-Language Community-Based Mental Health Treatment Programs, Policy-Required Language-Assistance Programming, and Mental Health Treatment Access Among Spanish-Speaking Clients

    PubMed Central

    McClellan, Sean R.

    2013-01-01

    Objectives. We investigated the extent to which implementing language assistance programming through contracting with community-based organizations improved the accessibility of mental health care under Medi-Cal (California’s Medicaid program) for Spanish-speaking persons with limited English proficiency, and whether it reduced language-based treatment access disparities. Methods. Using a time series nonequivalent control group design, we studied county-level penetration of language assistance programming over 10 years (1997–2006) for Spanish-speaking persons with limited English proficiency covered under Medi-Cal. We used linear regression with county fixed effects to control for ongoing trends and other influences. Results. When county mental health plans contracted with community-based organizations, those implementing language assistance programming increased penetration rates of Spanish-language mental health services under Medi-Cal more than other plans (0.28 percentage points, a 25% increase on average; P < .05). However, the increase was insufficient to significantly reduce language-related disparities. Conclusions. Mental health treatment programs operated by community-based organizations may have moderately improved access after implementing required language assistance programming, but the programming did not reduce entrenched disparities in the accessibility of mental health services. PMID:23865663

  6. Nociones de la programacion de lenguas extranjeras (Ensayo metodologico) (Programming Foreign Languages [A Methodological Study])

    ERIC Educational Resources Information Center

    Feldman, David

    1975-01-01

    Stresses the importance of language laboratories and other technical devices used in foreign language teaching, particularly in programed language instruction. Illustrates, by means of taxonomies, the various stages a foreign language learning program should follow. (Text is in Spanish.) (DS)

  7. Thermoreception and nociception of the skin: a classic paper of Bessou and Perl and analyses of thermal sensitivity during a student laboratory exercise.

    PubMed

    Kuhtz-Buschbeck, Johann P; Andresen, Wiebke; Göbel, Stephan; Gilster, René; Stick, Carsten

    2010-06-01

    About four decades ago, Perl and collaborators were the first ones who unambiguously identified specifically nociceptive neurons in the periphery. In their classic work, they recorded action potentials from single C-fibers of a cutaneous nerve in cats while applying carefully graded stimuli to the skin (Bessou P, Perl ER. Response of cutaneous sensory units with unmyelinated fibers to noxious stimuli. J Neurophysiol 32: 1025-1043, 1969). They discovered polymodal nociceptors, which responded to mechanical, thermal, and chemical stimuli in the noxious range, and differentiated them from low-threshold thermoreceptors. Their classic findings form the basis of the present method that undergraduate medical students experience during laboratory exercises of sensory physiology, namely, quantitative testing of the thermal detection and pain thresholds. This diagnostic method examines the function of thin afferent nerve fibers. We collected data from nearly 300 students that showed that 1) women are more sensitive to thermal detection and thermal pain at the thenar than men, 2) habituation shifts thermal pain thresholds during repetititve testing, 3) the cold pain threshold is rather variable and lower when tested after heat pain than in the reverse case (order effect), and 4) ratings of pain intensity on a visual analog scale are correlated with the threshold temperature for heat pain but not for cold pain. Median group results could be reproduced in a retest. Quantitative sensory testing of thermal thresholds is feasible and instructive in the setting of a laboratory exercise and is appreciated by the students as a relevant and interesting technique.

  8. An IBM 370 assembly language program verifier

    NASA Technical Reports Server (NTRS)

    Maurer, W. D.

    1977-01-01

    The paper describes a program written in SNOBOL which verifies the correctness of programs written in assembly language for the IBM 360 and 370 series of computers. The motivation for using assembly language as a source language for a program verifier was the realization that many errors in programs are caused by misunderstanding or ignorance of the characteristics of specific computers. The proof of correctness of a program written in assembly language must take these characteristics into account. The program has been compiled and is currently running at the Center for Academic and Administrative Computing of The George Washington University.

  9. Educator Language Ideologies and a Top-Down Dual Language Program

    ERIC Educational Resources Information Center

    Fitzsimmons-Doolan, Shannon; Palmer, Deborah; Henderson, Kathryn

    2017-01-01

    Dual language bilingual education (DLBE) programs are framed to reflect pluralist discourses (de Jong, E. [2013]. "Policy Discourses and U.S. Language in Education Policies." "Peabody Journal of Education" 88 (1): 98-111) and affiliated language ideologies. The continued expansion of DLBE programs not surprisingly brings to…

  10. Teaching Adaptability of Object-Oriented Programming Language Curriculum

    ERIC Educational Resources Information Center

    Zhu, Xiao-dong

    2012-01-01

    The evolution of object-oriented programming languages includes update of their own versions, update of development environments, and reform of new languages upon old languages. In this paper, the evolution analysis of object-oriented programming languages is presented in term of the characters and development. The notion of adaptive teaching upon…

  11. Innovative Second Language Education: Bilingual Immersion Programs.

    ERIC Educational Resources Information Center

    Snow, Marguerite Ann

    Bilingual immersion programs combine second language immersion for language majority children and bilingual education for language minority children. The programs are based on the underlying assumption of the immersion model: that a second language is best learned as a medium of instruction, not as the object of instruction. However, they are not…

  12. The BASIC Instructional Program: Conversion into MAINSAIL Language.

    ERIC Educational Resources Information Center

    Dageforde, Mary L.

    This report summarizes the rewriting of the BASIC Instructional Program (BIP) (a "hands-on laboratory" that teaches elementary programming in the BASIC language) from SAIL (a programming language available only on PDP-10 computers) into MAINSAIL (a language designed for portability on a broad class of computers). Four sections contain…

  13. NATAL-74; Towards a Common Programming Language for CAL.

    ERIC Educational Resources Information Center

    Brahan, J. W.; Colpitts, B. A.

    NATAL-74 is a programing language designed for Canadian computer aided learning (CAL) programs. The language has two fundamental elements: the UNIT provides the interface between the student and the subject matter, and the PROCEDURE element embodies teaching strategy. Desirable features of several programing languages have been adapted to cope…

  14. A high level language for a high performance computer

    NASA Technical Reports Server (NTRS)

    Perrott, R. H.

    1978-01-01

    The proposed computational aerodynamic facility will join the ranks of the supercomputers due to its architecture and increased execution speed. At present, the languages used to program these supercomputers have been modifications of programming languages which were designed many years ago for sequential machines. A new programming language should be developed based on the techniques which have proved valuable for sequential programming languages and incorporating the algorithmic techniques required for these supercomputers. The design objectives for such a language are outlined.

  15. “One code to find them all”: a perl tool to conveniently parse RepeatMasker output files

    PubMed Central

    2014-01-01

    Background Of the different bioinformatic methods used to recover transposable elements (TEs) in genome sequences, one of the most commonly used procedures is the homology-based method proposed by the RepeatMasker program. RepeatMasker generates several output files, including the .out file, which provides annotations for all detected repeats in a query sequence. However, a remaining challenge consists of identifying the different copies of TEs that correspond to the identified hits. This step is essential for any evolutionary/comparative analysis of the different copies within a family. Different possibilities can lead to multiple hits corresponding to a unique copy of an element, such as the presence of large deletions/insertions or undetermined bases, and distinct consensus corresponding to a single full-length sequence (like for long terminal repeat (LTR)-retrotransposons). These possibilities must be taken into account to determine the exact number of TE copies. Results We have developed a perl tool that parses the RepeatMasker .out file to better determine the number and positions of TE copies in the query sequence, in addition to computing quantitative information for the different families. To determine the accuracy of the program, we tested it on several RepeatMasker .out files corresponding to two organisms (Drosophila melanogaster and Homo sapiens) for which the TE content has already been largely described and which present great differences in genome size, TE content, and TE families. Conclusions Our tool provides access to detailed information concerning the TE content in a genome at the family level from the .out file of RepeatMasker. This information includes the exact position and orientation of each copy, its proportion in the query sequence, and its quality compared to the reference element. In addition, our tool allows a user to directly retrieve the sequence of each copy and obtain the same detailed information at the family level when a local library with incomplete TE class/subclass information was used with RepeatMasker. We hope that this tool will be helpful for people working on the distribution and evolution of TEs within genomes.

  16. Efficient self-consistency for magnetic tight binding

    NASA Astrophysics Data System (ADS)

    Soin, Preetma; Horsfield, A. P.; Nguyen-Manh, D.

    2011-06-01

    Tight binding can be extended to magnetic systems by including an exchange interaction on an atomic site that favours net spin polarisation. We have used a published model, extended to include long-ranged Coulomb interactions, to study defects in iron. We have found that achieving self-consistency using conventional techniques was either unstable or very slow. By formulating the problem of achieving charge and spin self-consistency as a search for stationary points of a Harris-Foulkes functional, extended to include spin, we have derived a much more efficient scheme based on a Newton-Raphson procedure. We demonstrate the capabilities of our method by looking at vacancies and self-interstitials in iron. Self-consistency can indeed be achieved in a more efficient and stable manner, but care needs to be taken to manage this. The algorithm is implemented in the code PLATO. Program summaryProgram title:PLATO Catalogue identifier: AEFC_v2_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEFC_v2_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 228 747 No. of bytes in distributed program, including test data, etc.: 1 880 369 Distribution format: tar.gz Programming language: C and PERL Computer: Apple Macintosh, PC, Unix machines Operating system: Unix, Linux, Mac OS X, Windows XP Has the code been vectorised or parallelised?: Yes. Up to 256 processors tested RAM: Up to 2 Gbytes per processor Classification: 7.3 External routines: LAPACK, BLAS and optionally ScaLAPACK, BLACS, PBLAS, FFTW Catalogue identifier of previous version: AEFC_v1_0 Journal reference of previous version: Comput. Phys. Comm. 180 (2009) 2616 Does the new version supersede the previous version?: Yes Nature of problem: Achieving charge and spin self-consistency in magnetic tight binding can be very difficult. Our existing schemes failed altogether, or were very slow. Solution method: A new scheme for achieving self-consistency in orthogonal tight binding has been introduced that explicitly evaluates the first and second derivatives of the energy with respect to input charge and spin, and then uses these to search for stationary values of the energy. Reasons for new version: Bug fixes and new functionality. Summary of revisions: New charge and spin mixing scheme for orthogonal tight binding. Numerous small bug fixes. Restrictions: The new mixing scheme scales poorly with system size. In particular the memory usage scales as number of atoms to the power 4. It is restricted to systems with about 200 atoms or less. Running time: Test cases will run in a few minutes, large calculations may run for several days.

  17. Survey of Speech-Language Pathology Graduate Program Training in Outer and Middle Ear Screening.

    PubMed

    Serpanos, Yula C; Senzer, Deborah

    2015-08-01

    The purpose of this study was to determine the national training practices of speech-language pathology graduate programs in outer and middle ear screening. Directors of all American Speech-Language-Hearing Association-accredited speech-language pathology graduate programs (N = 254; Council on Academic Accreditation in Audiology and Speech-Language Pathology, 2013) were surveyed on instructional formats in outer and middle ear screening. The graduate speech-language pathology program survey yielded 84 (33.1%) responses. Results indicated that some programs do not provide any training in the areas of conventional screening otoscopy using a handheld otoscope (15.5%; n = 13) or screening tympanometry (11.9%; n = 10), whereas close to one half (46.4%; n = 39) reported no training in screening video otoscopy. Outcomes revealed that approximately one third or more of speech-language pathology graduate programs do not provide experiential opportunities in screening handheld otoscopy (36.9%) or tympanometry (32.1%), and most (78.6%) do not provide experiential opportunities in video otoscopy. The implication from the graduate speech-language pathology program survey findings is that some speech-language pathologists will graduate from academic programs without the acquired knowledge or experiential learning required to establish skill in 1 or more areas of screening otoscopy and tympanometry. Graduate speech-language pathology programs should consider appropriate training opportunities for students to acquire and demonstrate skill in outer and middle ear screening.

  18. Investigating Principals' Knowledge and Perceptions of Second Language Programs for English Language Learners

    ERIC Educational Resources Information Center

    Padron, Yolanda N.; Waxman, Hersh C.

    2016-01-01

    This study examined principals' knowledge and perceptions of second language programs for English language learners (ELLs) operating in their schools. An open-ended survey and in-depth interviews were used to examine elementary school principals' knowledge of the second language programs implemented at their schools. The survey asked principals…

  19. Teachers' Perspectives on Academic Achievement and Educational Growth of U.S.-Born Hispanic Students in a Midwestern Spanish Language Immersion Program

    ERIC Educational Resources Information Center

    Salgado, Herlinda Arlene Galve

    2016-01-01

    Elementary Spanish language immersion programs have become more popular in the educational field in the United States to support the academic achievement of minority students. The final goal of immersion programs is to develop proficiency in the home language and dominant language, identified as first language (L1) and second language (L2), to…

  20. Accounting Data to Web Interface Using PERL

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hargeaves, C

    2001-08-13

    This document will explain the process to create a web interface for the accounting information generated by the High Performance Storage Systems (HPSS) accounting report feature. The accounting report contains useful data but it is not easily accessed in a meaningful way. The accounting report is the only way to see summarized storage usage information. The first step is to take the accounting data, make it meaningful and store the modified data in persistent databases. The second step is to generate the various user interfaces, HTML pages, that will be used to access the data. The third step is tomore » transfer all required files to the web server. The web pages pass parameters to Common Gateway Interface (CGI) scripts that generate dynamic web pages and graphs. The end result is a web page with specific information presented in text with or without graphs. The accounting report has a specific format that allows the use of regular expressions to verify if a line is storage data. Each storage data line is stored in a detailed database file with a name that includes the run date. The detailed database is used to create a summarized database file that also uses run date in its name. The summarized database is used to create the group.html web page that includes a list of all storage users. Scripts that query the database folder to build a list of available databases generate two additional web pages. A master script that is run monthly as part of a cron job, after the accounting report has completed, manages all of these individual scripts. All scripts are written in the PERL programming language. Whenever possible data manipulation scripts are written as filters. All scripts are written to be single source, which means they will function properly on both the open and closed networks at LLNL. The master script handles the command line inputs for all scripts, file transfers to the web server and records run information in a log file. The rest of the scripts manipulate the accounting data or use the files created to generate HTML pages. Each script will be described in detail herein. The following is a brief description of HPSS taken directly from an HPSS web site. ''HPSS is a major development project, which began in 1993 as a Cooperative Research and Development Agreement (CRADA) between government and industry. The primary objective of HPSS is to move very large data objects between high performance computers, workstation clusters, and storage libraries at speeds many times faster than is possible with today's software systems. For example, HPSS can manage parallel data transfers from multiple network-connected disk arrays at rates greater than 1 Gbyte per second, making it possible to access high definition digitized video in real time.'' The HPSS accounting report is a canned report whose format is controlled by the HPSS developers.« less

  1. Python to learn programming

    NASA Astrophysics Data System (ADS)

    Bogdanchikov, A.; Zhaparov, M.; Suliyev, R.

    2013-04-01

    Today we have a lot of programming languages that can realize our needs, but the most important question is how to teach programming to beginner students. In this paper we suggest using Python for this purpose, because it is a programming language that has neatly organized syntax and powerful tools to solve any task. Moreover it is very close to simple math thinking. Python is chosen as a primary programming language for freshmen in most of leading universities. Writing code in python is easy. In this paper we give some examples of program codes written in Java, C++ and Python language, and we make a comparison between them. Firstly, this paper proposes advantages of Python language in relation to C++ and JAVA. Then it shows the results of a comparison of short program codes written in three different languages, followed by a discussion on how students understand programming. Finally experimental results of students' success in programming courses are shown.

  2. Usability Issues in the Design of Novice Programming Systems,

    DTIC Science & Technology

    1996-08-01

    lists this as a design principle for novice programming environments. In traditional compiled languages, beginners are also confused by the need to...programming task external knowledge that might interfere with correct under- standing of the language. Most beginner programming errors can be...language for text editing, but [Curtis 1988] found that a textual pseudocode and graphical flowcharts were both bet- ter than natural language in program

  3. The Potential of CGI: Using Pre-Built CGI Scripts to Make Interactive Web Pages.

    ERIC Educational Resources Information Center

    Nackerud, Shane A.

    1998-01-01

    Describes CGI (Common Gateway Interface) scripts that are available on the Web and explains how librarians can use them to make Web pages more interactive. Topics include CGI security; Perl scripts; UNIX; and HTML. (LRW)

  4. The Surrogate Self

    ERIC Educational Resources Information Center

    Gunnison, Hugh

    1976-01-01

    The use of the "surrogate self" in counseling is a simple Gestalt-like role-playing technique (Perls 1969) that can be especially effective when the client has begun to see the counselor as a trusted, caring, and understanding person. The role-playing is described. (Author/EJT)

  5. Programming Languages.

    ERIC Educational Resources Information Center

    Tesler, Lawrence G.

    1984-01-01

    Discusses the nature of programing languages, considering the features of BASIC, LOGO, PASCAL, COBOL, FORTH, APL, and LISP. Also discusses machine/assembly codes, the operation of a compiler, and trends in the evolution of programing languages (including interest in notational systems called object-oriented languages). (JN)

  6. A Common Programming Language for the Department of Defense--Background and Technical Requirements

    DTIC Science & Technology

    1976-06-01

    Method Findings I. Introduction A. The Problem 1. Software Costs 2. Programming Language 3. Lack of Comrr.onality 4. Common Language 5...accessible soft- ware tools and aids. There are a number of widely held perceptions about the ill effects of the lack of programming language ...cost- effective (at lea~t during development) than de- velopi~g a new programming language specialized to the project. On the other hand,

  7. What Is a Programming Language?

    ERIC Educational Resources Information Center

    Wold, Allen

    1983-01-01

    Explains what a computer programing language is in general, the differences between machine language, assembler languages, and high-level languages, and the functions of compilers and interpreters. High-level languages mentioned in the article are: BASIC, FORTRAN, COBOL, PILOT, LOGO, LISP, and SMALLTALK. (EAO)

  8. Total Immersion Language Program: A New Approach to Foreign Language Instruction. Technical Report.

    ERIC Educational Resources Information Center

    Morel, Stefano

    A three-year experimental program established in 1966 in Spanish language instruction at the secondary level is reported in this study. Students at Commack High School North, New York, participated in a total immersion language program in Spanish, taking two to four classes of instruction in the target language per day. Classes included regular…

  9. 34 CFR 658.4 - What definitions apply to the Undergraduate International Studies and Foreign Language Program?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... International Studies and Foreign Language Program? 658.4 Section 658.4 Education Regulations of the Offices of... UNDERGRADUATE INTERNATIONAL STUDIES AND FOREIGN LANGUAGE PROGRAM General § 658.4 What definitions apply to the Undergraduate International Studies and Foreign Language Program? The definitions in 34 CFR 655.4 apply to this...

  10. 34 CFR 658.4 - What definitions apply to the Undergraduate International Studies and Foreign Language Program?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... International Studies and Foreign Language Program? 658.4 Section 658.4 Education Regulations of the Offices of... UNDERGRADUATE INTERNATIONAL STUDIES AND FOREIGN LANGUAGE PROGRAM General § 658.4 What definitions apply to the Undergraduate International Studies and Foreign Language Program? The definitions in 34 CFR 655.4 apply to this...

  11. Students' Perspective on the First Programming Language: C-Like or Pascal-Like Languages?

    ERIC Educational Resources Information Center

    Xinogalos, Stelios; Pitner, Tomáš; Ivanovic, Mirjana; Savic, Miloš

    2018-01-01

    The choice of the first programming language (FPL) has been a controversial issue for several decades. Nearly everyone agrees that the FPL is important and affects students' subsequent education on programming. The study presented in this article investigates the suitability of various C-like and Pascal-like programming languages as a FPL.…

  12. HAL/SM language specification. [programming languages and computer programming for space shuttles

    NASA Technical Reports Server (NTRS)

    Williams, G. P. W., Jr.; Ross, C.

    1975-01-01

    A programming language is presented for the flight software of the NASA Space Shuttle program. It is intended to satisfy virtually all of the flight software requirements of the space shuttle. To achieve this, it incorporates a wide range of features, including applications-oriented data types and organizations, real time control mechanisms, and constructs for systems programming tasks. It is a higher order language designed to allow programmers, analysts, and engineers to communicate with the computer in a form approximating natural mathematical expression. Parts of the English language are combined with standard notation to provide a tool that readily encourages programming without demanding computer hardware expertise. Block diagrams and flow charts are included. The semantics of the language is discussed.

  13. Artificial intelligence programming languages for computer aided manufacturing

    NASA Technical Reports Server (NTRS)

    Rieger, C.; Samet, H.; Rosenberg, J.

    1979-01-01

    Eight Artificial Intelligence programming languages (SAIL, LISP, MICROPLANNER, CONNIVER, MLISP, POP-2, AL, and QLISP) are presented and surveyed, with examples of their use in an automated shop environment. Control structures are compared, and distinctive features of each language are highlighted. A simple programming task is used to illustrate programs in SAIL, LISP, MICROPLANNER, and CONNIVER. The report assumes reader knowledge of programming concepts, but not necessarily of the languages surveyed.

  14. Innovative Technology for Teaching Introductory Astronomy

    NASA Astrophysics Data System (ADS)

    Guidry, Mike

    The application of state-of-the-art technology (primarily Java and Flash MX Actionscript on the client side and Java PHP PERL XML and SQL databasing on the server side) to the teaching of introductory astronomy will be discussed. A completely online syllabus in introductory astronomy built around more than 350 interactive animations called ""Online Journey through Astronomy"" and a new set of 20 online virtual laboratories in astronomy that we are currently developing will be used as illustration. In addition to demonstration of the technology our experience using these technologies to teach introductory astronomy to thousands of students in settings ranging from traditional classrooms to full distance learning will be summarized. Recent experiments using Java and vector graphics programming of handheld devices (Personal Digital Assistants and cell phones) with wireless wide-area connectivity for applications in astronomy education will also be described.

  15. Calypso: a user-friendly web-server for mining and visualizing microbiome-environment interactions.

    PubMed

    Zakrzewski, Martha; Proietti, Carla; Ellis, Jonathan J; Hasan, Shihab; Brion, Marie-Jo; Berger, Bernard; Krause, Lutz

    2017-03-01

    Calypso is an easy-to-use online software suite that allows non-expert users to mine, interpret and compare taxonomic information from metagenomic or 16S rDNA datasets. Calypso has a focus on multivariate statistical approaches that can identify complex environment-microbiome associations. The software enables quantitative visualizations, statistical testing, multivariate analysis, supervised learning, factor analysis, multivariable regression, network analysis and diversity estimates. Comprehensive help pages, tutorials and videos are provided via a wiki page. The web-interface is accessible via http://cgenome.net/calypso/ . The software is programmed in Java, PERL and R and the source code is available from Zenodo ( https://zenodo.org/record/50931 ). The software is freely available for non-commercial users. l.krause@uq.edu.au. Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press.

  16. Aerobraking Maneuver (ABM) Report Generator

    NASA Technical Reports Server (NTRS)

    Fisher, Forrest; Gladden, Roy; Khanampornpan, Teerapat

    2008-01-01

    abmREPORT Version 3.1 is a Perl script that extracts vital summarization information from the Mars Reconnaissance Orbiter (MRO) aerobraking ABM build process. This information facilitates sequence reviews, and provides a high-level summarization of the sequence for mission management. The script extracts information from the ENV, SSF, FRF, SCMFmax, and OPTG files and burn magnitude configuration files and presents them in a single, easy-to-check report that provides the majority of the parameters necessary for cross check and verification during the sequence review process. This means that needed information, formerly spread across a number of different files and each in a different format, is all available in this one application. This program is built on the capabilities developed in dragReport and then the scripts evolved as the two tools continued to be developed in parallel.

  17. Telemetry-Enhancing Scripts

    NASA Technical Reports Server (NTRS)

    Maimone, Mark W.

    2009-01-01

    Scripts Providing a Cool Kit of Telemetry Enhancing Tools (SPACKLE) is a set of software tools that fill gaps in capabilities of other software used in processing downlinked data in the Mars Exploration Rovers (MER) flight and test-bed operations. SPACKLE tools have helped to accelerate the automatic processing and interpretation of MER mission data, enabling non-experts to understand and/or use MER query and data product command simulation software tools more effectively. SPACKLE has greatly accelerated some operations and provides new capabilities. The tools of SPACKLE are written, variously, in Perl or the C or C++ language. They perform a variety of search and shortcut functions that include the following: Generating text-only, Event Report-annotated, and Web-enhanced views of command sequences; Labeling integer enumerations with their symbolic meanings in text messages and engineering channels; Systematic detecting of corruption within data products; Generating text-only displays of data-product catalogs including downlink status; Validating and labeling of commands related to data products; Performing of convenient searches of detailed engineering data spanning multiple Martian solar days; Generating tables of initial conditions pertaining to engineering, health, and accountability data; Simplified construction and simulation of command sequences; and Fast time format conversions and sorting.

  18. Development of Human Face Literature Database Using Text Mining Approach: Phase I.

    PubMed

    Kaur, Paramjit; Krishan, Kewal; Sharma, Suresh K

    2018-06-01

    The face is an important part of the human body by which an individual communicates in the society. Its importance can be highlighted by the fact that a person deprived of face cannot sustain in the living world. The amount of experiments being performed and the number of research papers being published under the domain of human face have surged in the past few decades. Several scientific disciplines, which are conducting research on human face include: Medical Science, Anthropology, Information Technology (Biometrics, Robotics, and Artificial Intelligence, etc.), Psychology, Forensic Science, Neuroscience, etc. This alarms the need of collecting and managing the data concerning human face so that the public and free access of it can be provided to the scientific community. This can be attained by developing databases and tools on human face using bioinformatics approach. The current research emphasizes on creating a database concerning literature data of human face. The database can be accessed on the basis of specific keywords, journal name, date of publication, author's name, etc. The collected research papers will be stored in the form of a database. Hence, the database will be beneficial to the research community as the comprehensive information dedicated to the human face could be found at one place. The information related to facial morphologic features, facial disorders, facial asymmetry, facial abnormalities, and many other parameters can be extracted from this database. The front end has been developed using Hyper Text Mark-up Language and Cascading Style Sheets. The back end has been developed using hypertext preprocessor (PHP). The JAVA Script has used as scripting language. MySQL (Structured Query Language) is used for database development as it is most widely used Relational Database Management System. XAMPP (X (cross platform), Apache, MySQL, PHP, Perl) open source web application software has been used as the server.The database is still under the developmental phase and discusses the initial steps of its creation. The current paper throws light on the work done till date.

  19. Development of a Computing Cluster At the University of Richmond

    NASA Astrophysics Data System (ADS)

    Carbonneau, J.; Gilfoyle, G. P.; Bunn, E. F.

    2010-11-01

    The University of Richmond has developed a computing cluster to support the massive simulation and data analysis requirements for programs in intermediate-energy nuclear physics, and cosmology. It is a 20-node, 240-core system running Red Hat Enterprise Linux 5. We have built and installed the physics software packages (Geant4, gemc, MADmap...) and developed shell and Perl scripts for running those programs on the remote nodes. The system has a theoretical processing peak of about 2500 GFLOPS. Testing with the High Performance Linpack (HPL) benchmarking program (one of the standard benchmarks used by the TOP500 list of fastest supercomputers) resulted in speeds of over 900 GFLOPS. The difference between the maximum and measured speeds is due to limitations in the communication speed among the nodes; creating a bottleneck for large memory problems. As HPL sends data between nodes, the gigabit Ethernet connection cannot keep up with the processing power. We will show how both the theoretical and actual performance of the cluster compares with other current and past clusters, as well as the cost per GFLOP. We will also examine the scaling of the performance when distributed to increasing numbers of nodes.

  20. Heritage Language Education: Valuing the Languages, Literacies, and Cultural Competencies of Immigrant Youth

    ERIC Educational Resources Information Center

    Seals, Corinne A.; Peyton, Joy Kreeft

    2017-01-01

    This article argues for the value of heritage language programs and the micro-level language policies that support them, focusing on a case study of a program in the USA to make this argument. We also argue for the importance of recognizing students' heritage languages, cultures, and individual goals and identities in mainstream school programs.…

  1. Do They Make a Difference? The Impact of English Language Programs on Second Language Students in Canadian Universities

    ERIC Educational Resources Information Center

    Fox, Janna; Cheng, Liying; Zumbo, Bruno D.

    2014-01-01

    Few studies have investigated the impact of English language programs on second language (L2) students studying in Canadian universities (Cheng & Fox, 2008; Fox, 2005, 2009). This article reports on questionnaire responses of 641 L2 students studying in 36 English language programs in 26 Canadian universities. The researchers identified…

  2. An Evaluation Framework and Comparative Analysis of the Widely Used First Programming Languages

    PubMed Central

    Farooq, Muhammad Shoaib; Khan, Sher Afzal; Ahmad, Farooq; Islam, Saeed; Abid, Adnan

    2014-01-01

    Computer programming is the core of computer science curriculum. Several programming languages have been used to teach the first course in computer programming, and such languages are referred to as first programming language (FPL). The pool of programming languages has been evolving with the development of new languages, and from this pool different languages have been used as FPL at different times. Though the selection of an appropriate FPL is very important, yet it has been a controversial issue in the presence of many choices. Many efforts have been made for designing a good FPL, however, there is no ample way to evaluate and compare the existing languages so as to find the most suitable FPL. In this article, we have proposed a framework to evaluate the existing imperative, and object oriented languages for their suitability as an appropriate FPL. Furthermore, based on the proposed framework we have devised a customizable scoring function to compute a quantitative suitability score for a language, which reflects its conformance to the proposed framework. Lastly, we have also evaluated the conformance of the widely used FPLs to the proposed framework, and have also computed their suitability scores. PMID:24586449

  3. An evaluation framework and comparative analysis of the widely used first programming languages.

    PubMed

    Farooq, Muhammad Shoaib; Khan, Sher Afzal; Ahmad, Farooq; Islam, Saeed; Abid, Adnan

    2014-01-01

    Computer programming is the core of computer science curriculum. Several programming languages have been used to teach the first course in computer programming, and such languages are referred to as first programming language (FPL). The pool of programming languages has been evolving with the development of new languages, and from this pool different languages have been used as FPL at different times. Though the selection of an appropriate FPL is very important, yet it has been a controversial issue in the presence of many choices. Many efforts have been made for designing a good FPL, however, there is no ample way to evaluate and compare the existing languages so as to find the most suitable FPL. In this article, we have proposed a framework to evaluate the existing imperative, and object oriented languages for their suitability as an appropriate FPL. Furthermore, based on the proposed framework we have devised a customizable scoring function to compute a quantitative suitability score for a language, which reflects its conformance to the proposed framework. Lastly, we have also evaluated the conformance of the widely used FPLs to the proposed framework, and have also computed their suitability scores.

  4. Knowledge, programming, and programming cultures: LISP, C, and Ada

    NASA Technical Reports Server (NTRS)

    Rochowiak, Daniel

    1990-01-01

    The results of research 'Ada as an implementation language for knowledge based systems' are presented. The purpose of the research was to compare Ada to other programming languages. The report focuses on the programming languages Ada, C, and Lisp, the programming cultures that surround them, and the programming paradigms they support.

  5. Climate Prediction Center - Reanalysis: Atmospheric Data

    Science.gov Websites

    files; i.e., wgrib for GRIB-2 files wgrib2mv,wgrib2ms parallel processing with wgrib2 grb1to2.pl perl US government, DOC, NWS, NCEP or CPC. All spelling errors are property of the finder. comments

  6. The African Language Program at Michigan State University.

    ERIC Educational Resources Information Center

    Dwyer, David

    1979-01-01

    Describes the African language program at Michigan State University, which provides (1) supervised, individualized instruction for high-demand languages, on two levels; (2) regular classroom instruction for Swahili and Hausa; and (3) non-credit, self-instructional programs for low-demand languages. Sample forms are appended. (AM)

  7. Computer Programming Languages for Health Care

    PubMed Central

    O'Neill, Joseph T.

    1979-01-01

    This paper advocates the use of standard high level programming languages for medical computing. It recommends that U.S. Government agencies having health care missions implement coordinated policies that encourage the use of existing standard languages and the development of new ones, thereby enabling them and the medical computing community at large to share state-of-the-art application programs. Examples are based on a model that characterizes language and language translator influence upon the specification, development, test, evaluation, and transfer of application programs.

  8. Flight program language requirements. Volume 3: Appendices

    NASA Technical Reports Server (NTRS)

    1972-01-01

    Government-sponsored study and development efforts were directed toward design and implementation of high level programming languages suitable for future aerospace applications. The study centered around an evaluation of the four most pertinent existing aerospace languages. Evaluation criteria were established, and selected kernels from the current Saturn 5 and Skylab flight programs were used as benchmark problems for sample coding. An independent review of the language specifications incorporated anticipated future programming requirements into the evaluation. A set of language requirements was synthesized from these activities.

  9. A Model of RHIC Using the Unified Accelerator Libraries

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pilat, F.; Tepikian, S.; Trahern, C. G.

    1998-01-01

    The Unified Accelerator Library (UAL) is an object oriented and modular software environment for accelerator physics which comprises an accelerator object model for the description of the machine (SMF, for Standard Machine Format), a collection of Physics Libraries, and a Perl inte,face that provides a homo­geneous shell for integrating and managing these components. Currently available physics libraries include TEAPOT++, a collection of C++ physics modules conceptually derived from TEAPOT, and DNZLIB, a differential algebra package for map generation. This software environment has been used to build a flat model of RHIC which retains the hierarchical lat­tice description while assigning specificmore » characteristics to individual elements, such as measured field har­monics. A first application of the model and of the simulation capabilities of UAL has been the study of RHIC stability in the presence of siberian snakes and spin rotators. The building blocks of RHIC snakes and rotators are helical dipoles, unconventional devices that can not be modeled by traditional accelerator phys­ics codes and have been implemented in UAL as Taylor maps. Section 2 describes the RHIC data stores, Section 3 the RHIC SMF format and Section 4 the RHIC spe­cific Perl interface (RHIC Shell). Section 5 explains how the RHIC SMF and UAL have been used to study the RHIC dynamic behavior and presents detuning and dynamic aperture results. If the reader is not familiar with the motivation and characteristics of UAL, we include in the Appendix an useful overview paper. An example of a complete set of Perl Scripts for RHIC simulation can also be found in the Appendix.« less

  10. Praxis language reference manual

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Walker, J.H.

    1981-01-01

    This document is a language reference manual for the programming language Praxis. The document contains the specifications that must be met by any compiler for the language. The Praxis language was designed for systems programming in real-time process applications. Goals for the language and its implementations are: (1) highly efficient code generated by the compiler; (2) program portability; (3) completeness, that is, all programming requirements can be met by the language without needing an assembler; and (4) separate compilation to aid in design and management of large systems. The language does not provide any facilities for input/output, stack and queuemore » handling, string operations, parallel processing, or coroutine processing. These features can be implemented as routines in the language, using machine-dependent code to take advantage of facilities in the control environment on different machines.« less

  11. Visual Programming: A Programming Tool for Increasing Mathematics Achivement

    ERIC Educational Resources Information Center

    Swanier, Cheryl A.; Seals, Cheryl D.; Billionniere, Elodie V.

    2009-01-01

    This paper aims to address the need of increasing student achievement in mathematics using a visual programming language such as Scratch. This visual programming language facilitates creating an environment where students in K-12 education can develop mathematical simulations while learning a visual programming language at the same time.…

  12. Problems for a Sign Language Planning Agency

    ERIC Educational Resources Information Center

    Covington, Virginia

    1977-01-01

    American Sign Language is chiefly untaught and nonstandardized. The Communicative Skills Program of the National Association of the Deaf aims to provide sign language classes for hearing personnel and to increase interpreting services. Programs, funding and aims of the Program are outlined. A government sign language planning agency is proposed.…

  13. A Year-Round Professional Development Model for World Language Educators

    ERIC Educational Resources Information Center

    Steele, Tracy M.; Peterson, Margaret D.; Silva, Duarte M.; Padilla, Amado M.

    2009-01-01

    The Bay Area Foreign Language Program (BAFLP), one of nine regional sites of the California Foreign Language Project, offers ongoing, year-round professional development programs for world language educators. In addition, its leadership program prepares selected educators to assume leadership positions at their school sites, building capacity for…

  14. Quantitative Model for Choosing Programming Language for Online Instruction

    ERIC Educational Resources Information Center

    Sherman, Steven J.; Shehane, Ronald F.; Todd, Dewey W.

    2018-01-01

    Colleges are increasingly offering online courses, including computer programming courses for business school students. Programming languages that are most useful to students are those that are widely used in the job market. However, the most popular computer languages change at least every three years. Therefore, the language used for instruction…

  15. Foreign Language K-12. Program Evaluation 1991-92.

    ERIC Educational Resources Information Center

    Wadden, Jerry M.

    The Des Moines (Iowa) Public Schools foreign language program for K-12 is described and evaluated. The evaluation report focuses on six areas, including: (1) school district mission and philosophy of foreign language instruction; (2) context (state policies and standards, foreign language program overview and enrollment, fiber-optic communication…

  16. Les programmes de base: des principes a la realite (Core Programs: From Principles to Reality).

    ERIC Educational Resources Information Center

    Calve, Pierre

    1985-01-01

    The recent evolution of second language teaching theory regarding language, learning, communication, and teaching is summarized, and factors contributing to resistance to core second language programs are examined. They include tradition, school programs, time of instruction, language of instruction, teacher training, attitudes, and…

  17. 77 FR 30045 - 30-Day Notice of Proposed Information Collection: English Language Evaluation Surveys

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-21

    ...] 30-Day Notice of Proposed Information Collection: English Language Evaluation Surveys ACTION: Notice... clearance will allow ECA/P/V, as part of the English Language Evaluation, to conduct surveys of participants in the ETA Program, E-Teacher Scholarship program, and the English Language Specialist Program...

  18. Listen! Native Radio Can Save Languages.

    ERIC Educational Resources Information Center

    Martin, Kallen

    1996-01-01

    In the United States and Canada, the number of radio stations operated by Native Americans has greatly increased in recent years, as have the amount of programming in native languages and the number of native language instructional programs. Such programming can play a role in maintaining vigorous native languages and revitalizing endangered…

  19. Synchronization in Scratch: A Case Study with Education Science Students

    ERIC Educational Resources Information Center

    Nikolos, Dimitris; Komis, Vassilis

    2015-01-01

    The Scratch programming language is an introductory programming language for students. It is also a visual concurrent programming language, where multiple threads are executed simultaneously. Synchronization in concurrent languages is a complex task for novices to understand. Our research is focused on strategies and methods applied by novice…

  20. At the Crossroads of Learning and Culture: Identifying a Construct for Effective Computer-Assisted Language Learning for English Language Learners

    ERIC Educational Resources Information Center

    Shaw, Yun

    2010-01-01

    Many of the commercial Computer-Assisted Language Learning (CALL) programs available today typically take a generic approach. This approach standardizes the program so that it can be used to teach any language merely by translating the content from one language to another. These CALL programs rarely consider the cultural background or preferred…

  1. Towards the Automatic Generation of Programmed Foreign-Language Instructional Materials.

    ERIC Educational Resources Information Center

    Van Campen, Joseph A.

    The purpose of this report is to describe a set of programs which either perform certain tasks useful in the generation of programed foreign-language instructional material or facilitate the writing of such task-oriented programs by other researchers. The programs described are these: (1) a PDP-10 assembly language program for the selection from a…

  2. Programming Language Use in US Academia and Industry

    ERIC Educational Resources Information Center

    Ben Arfa Rabai, Latifa; Cohen, Barry; Mili, Ali

    2015-01-01

    In the same way that natural languages influence and shape the way we think, programming languages have a profound impact on the way a programmer analyzes a problem and formulates its solution in the form of a program. To the extent that a first programming course is likely to determine the student's approach to program design, program analysis,…

  3. Teacher and Student Language Practices and Ideologies in a Third-Grade Two-Way Dual Language Program Implementation

    ERIC Educational Resources Information Center

    Henderson, Kathryn I.; Palmer, Deborah K.

    2015-01-01

    This article provides an in-depth exploration of the language ecologies of two classrooms attempting to implement a two-way dual language (TWDL) program and its mediating conditions. Drawing on ethnographic methods and a sociocultural understanding of language, we examined both teachers' and students' language ideologies and language practices,…

  4. Chief Dull Knife Community Is Strengthening the Northern Cheyenne Language and Culture.

    ERIC Educational Resources Information Center

    Littlebear, Richard E.

    2003-01-01

    Language revitalization programs should focus on whether they want to teach the language, teach about the language, teach with the language, or teach the language for academic credit. A program at Chief Dull Knife College (Montana) teaches the Cheyenne language using the Total Physical Response method, which replicates the manner in which first…

  5. Language plus for international graduate students in nursing.

    PubMed

    Julian, M A; Keane, A; Davidson, K

    1999-01-01

    To provide information about an English-language support program that focuses on the needs of international graduate nursing students. The growing presence of these students coincides with the increasing numbers of universities committed to world health. Crucial social and language competence affect the success and progress of international students in graduate nursing programs. Reviewed literature was 1980 to 1998, in nursing and applied linguistic research including second-language acquisition, phonology, discourse analysis, and language pragmatics to identify social and language phenomena. Investigators suggest essential elements such as conventions of academic writing, reading comprehension, vocabulary, and pronunciation skills be included in the supportive Language Plus program. Ongoing development of the Language Plus program can promote collaboration between nurses and linguists and increase the success of international graduate nursing students.

  6. BerkeleyGW: A massively parallel computer package for the calculation of the quasiparticle and optical properties of materials and nanostructures

    NASA Astrophysics Data System (ADS)

    Deslippe, Jack; Samsonidze, Georgy; Strubbe, David A.; Jain, Manish; Cohen, Marvin L.; Louie, Steven G.

    2012-06-01

    BerkeleyGW is a massively parallel computational package for electron excited-state properties that is based on the many-body perturbation theory employing the ab initio GW and GW plus Bethe-Salpeter equation methodology. It can be used in conjunction with many density-functional theory codes for ground-state properties, including PARATEC, PARSEC, Quantum ESPRESSO, SIESTA, and Octopus. The package can be used to compute the electronic and optical properties of a wide variety of material systems from bulk semiconductors and metals to nanostructured materials and molecules. The package scales to 10 000s of CPUs and can be used to study systems containing up to 100s of atoms. Program summaryProgram title: BerkeleyGW Catalogue identifier: AELG_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AELG_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Open source BSD License. See code for licensing details. No. of lines in distributed program, including test data, etc.: 576 540 No. of bytes in distributed program, including test data, etc.: 110 608 809 Distribution format: tar.gz Programming language: Fortran 90, C, C++, Python, Perl, BASH Computer: Linux/UNIX workstations or clusters Operating system: Tested on a variety of Linux distributions in parallel and serial as well as AIX and Mac OSX RAM: (50-2000) MB per CPU (Highly dependent on system size) Classification: 7.2, 7.3, 16.2, 18 External routines: BLAS, LAPACK, FFTW, ScaLAPACK (optional), MPI (optional). All available under open-source licenses. Nature of problem: The excited state properties of materials involve the addition or subtraction of electrons as well as the optical excitations of electron-hole pairs. The excited particles interact strongly with other electrons in a material system. This interaction affects the electronic energies, wavefunctions and lifetimes. It is well known that ground-state theories, such as standard methods based on density-functional theory, fail to correctly capture this physics. Solution method: We construct and solve the Dyson's equation for the quasiparticle energies and wavefunctions within the GW approximation for the electron self-energy. We additionally construct and solve the Bethe-Salpeter equation for the correlated electron-hole (exciton) wavefunctions and excitation energies. Restrictions: The material size is limited in practice by the computational resources available. Materials with up to 500 atoms per periodic cell can be studied on large HPCs. Additional comments: The distribution file for this program is approximately 110 Mbytes and therefore is not delivered directly when download or E-mail is requested. Instead a html file giving details of how the program can be obtained is sent. Running time: 1-1000 minutes (depending greatly on system size and processor number).

  7. Multidimensional Perception of Counselor Behavior

    ERIC Educational Resources Information Center

    Barak, Azy; LaCrosse, Michael B.

    1975-01-01

    Investigated Strong's prediction of the existence of three dimensions of perceived counselor behavior--expertness, attractiveness, and trustworthiness. Films of interviews given by Rogers, Ellis, and Perls were watched by 202 subjects, who rated each counselor on 36 bipolar scales. Results supported the existence of the hypothesized dimensions for…

  8. Dynamic Subcellular Localization of Iron during Embryo Development in Brassicaceae Seeds

    PubMed Central

    Ibeas, Miguel A.; Grant-Grant, Susana; Navarro, Nathalia; Perez, M. F.; Roschzttardtz, Hannetz

    2017-01-01

    Iron is an essential micronutrient for plants. Little is know about how iron is loaded in embryo during seed development. In this article we used Perls/DAB staining in order to reveal iron localization at the cellular and subcellular levels in different Brassicaceae seed species. In dry seeds of Brassica napus, Nasturtium officinale, Lepidium sativum, Camelina sativa, and Brassica oleracea iron localizes in vacuoles of cells surrounding provasculature in cotyledons and hypocotyl. Using B. napus and N. officinale as model plants we determined where iron localizes during seed development. Our results indicate that iron is not detectable by Perls/DAB staining in heart stage embryo cells. Interestingly, at torpedo development stage iron localizes in nuclei of different cells type, including integument, free cell endosperm and almost all embryo cells. Later, iron is detected in cytoplasmic structures in different embryo cell types. Our results indicate that iron accumulates in nuclei in specific stages of embryo maturation before to be localized in vacuoles of cells surrounding provasculature in mature seeds. PMID:29312417

  9. The HEASARC Swift Gamma-Ray Burst Archive: The Pipeline and the Catalog

    NASA Technical Reports Server (NTRS)

    Donato, Davide; Angelini, Lorella; Padgett, C.A.; Reichard, T.; Gehrels, Neil; Marshall, Francis E.; Sakamoto, Takanori

    2012-01-01

    Since its launch in late 2004, the Swift satellite triggered or observed an average of one gamma-ray burst (GRB) every 3 days, for a total of 771 GRBs by 2012 January. Here, we report the development of a pipeline that semi automatically performs the data-reduction and data-analysis processes for the three instruments on board Swift (BAT, XRT, UVOT). The pipeline is written in Perl, and it uses only HEAsoft tools and can be used to perform the analysis of a majority of the point-like objects (e.g., GRBs, active galactic nuclei, pulsars) observed by Swift. We run the pipeline on the GRBs, and we present a database containing the screened data, the output products, and the results of our ongoing analysis. Furthermore, we created a catalog summarizing some GRB information, collected either by running the pipeline or from the literature. The Perl script, the database, and the catalog are available for downloading and querying at the HEASARC Web site.

  10. pacce: Perl algorithm to compute continuum and equivalent widths

    NASA Astrophysics Data System (ADS)

    Riffel, Rogério; Borges Vale, Tibério

    2011-08-01

    We present Perl Algorithm to Compute continuum and Equivalent Widths ( pacce). We describe the methods used in the computations and the requirements for its usage. We compare the measurements made with pacce and "manual" ones made using iraf splot task. These tests show that for synthetic simple stellar population (SSP) models the equivalent widths strengths are very similar (differences ≲0.2 Å) for both measurements. In real stellar spectra, the correlation between both values is still very good, but with differences of up to 0.5 Å. pacce is also able to determine mean continuum and continuum at line center values, which are helpful in stellar population studies. In addition, it is also able to compute the uncertainties in the equivalent widths using photon statistics. The code is made available for the community through the web at http://www.if.ufrgs.br/~riffel/software.html .

  11. The HEASARC Swift Gamma-Ray Burst Archive: The Pipeline and the Catalog

    NASA Astrophysics Data System (ADS)

    Donato, D.; Angelini, L.; Padgett, C. A.; Reichard, T.; Gehrels, N.; Marshall, F. E.; Sakamoto, T.

    2012-11-01

    Since its launch in late 2004, the Swift satellite triggered or observed an average of one gamma-ray burst (GRB) every 3 days, for a total of 771 GRBs by 2012 January. Here, we report the development of a pipeline that semi-automatically performs the data-reduction and data-analysis processes for the three instruments on board Swift (BAT, XRT, UVOT). The pipeline is written in Perl, and it uses only HEAsoft tools and can be used to perform the analysis of a majority of the point-like objects (e.g., GRBs, active galactic nuclei, pulsars) observed by Swift. We run the pipeline on the GRBs, and we present a database containing the screened data, the output products, and the results of our ongoing analysis. Furthermore, we created a catalog summarizing some GRB information, collected either by running the pipeline or from the literature. The Perl script, the database, and the catalog are available for downloading and querying at the HEASARC Web site.

  12. A strategy for automatically generating programs in the lucid programming language

    NASA Technical Reports Server (NTRS)

    Johnson, Sally C.

    1987-01-01

    A strategy for automatically generating and verifying simple computer programs is described. The programs are specified by a precondition and a postcondition in predicate calculus. The programs generated are in the Lucid programming language, a high-level, data-flow language known for its attractive mathematical properties and ease of program verification. The Lucid programming is described, and the automatic program generation strategy is described and applied to several example problems.

  13. Award-Winning Foreign Language Programs: Prescriptions for Success.

    ERIC Educational Resources Information Center

    Sims, William D.; Hammond, Sandra B.

    The study reviews 50 foreign language programs in the United States that are said to be both inspirational and useful for providing concrete information about the creation and preservation of successful language programs. The programs cited are exemplary and can serve as models for educators and administrators to study and visit. Program selection…

  14. Laboratory automation in a functional programming language.

    PubMed

    Runciman, Colin; Clare, Amanda; Harkness, Rob

    2014-12-01

    After some years of use in academic and research settings, functional languages are starting to enter the mainstream as an alternative to more conventional programming languages. This article explores one way to use Haskell, a functional programming language, in the development of control programs for laboratory automation systems. We give code for an example system, discuss some programming concepts that we need for this example, and demonstrate how the use of functional programming allows us to express and verify properties of the resulting code. © 2014 Society for Laboratory Automation and Screening.

  15. Language Program Evaluation

    ERIC Educational Resources Information Center

    Norris, John M.

    2016-01-01

    Language program evaluation is a pragmatic mode of inquiry that illuminates the complex nature of language-related interventions of various kinds, the factors that foster or constrain them, and the consequences that ensue. Program evaluation enables a variety of evidence-based decisions and actions, from designing programs and implementing…

  16. Testing as a Way to Monitor English as a Foreign Language Learning

    ERIC Educational Resources Information Center

    Becker, Anthony; Nekrasova-Beker, Tatiana; Petrashova, Tamara

    2017-01-01

    This study was conducted at a large technical university in Russia, which offers English language courses to students majoring in nine different degree programs. Each degree program develops and delivers its own English language curriculum. While all degree programs followed the same curriculum development model to design language courses, each…

  17. A Program That Acquires Language Using Positive and Negative Feedback.

    ERIC Educational Resources Information Center

    Brand, James

    1987-01-01

    Describes the language learning program "Acquire," which is a sample of grammar induction. It is a learning algorithm based on a pattern-matching scheme, using both a positive and negative network to reduce overgeneration. Language learning programs may be useful as tutorials for learning the syntax of a foreign language. (Author/LMO)

  18. The English Language in the School Program.

    ERIC Educational Resources Information Center

    Hogan, Robert F., Ed.

    The 22 papers in this publication, drawn from the 1963 and 1964 NCTE Spring Institutes on Language, Linguistics, and School Programs, concentrate on the relevance of recent scholarship for English language programs in elementary and secondary schools. Language theory is the focus of articles by Harold B. Allen, Sumner Ives, Albert H. Marckwardt,…

  19. A Career-Oriented Foreign Language Program for Keystone Oaks School District, Pittsburgh, Pennsylvania.

    ERIC Educational Resources Information Center

    Grubesky, Marcia R.

    A career-oriented foreign language program is discussed that takes into account marketable skills of foreign language majors for a number of careers. The program is threefold. First, it recognizes the need for language skills to supplement technical, business, and professional skills to expand educational knowledge; capabilities in diplomacy and…

  20. The Effects of Web 2.0 Technologies Usage in Programming Languages Lesson on the Academic Success, Interrogative Learning Skills and Attitudes of Students towards Programming Languages

    ERIC Educational Resources Information Center

    Gençtürk, Abdullah Tarik; Korucu, Agah Tugrul

    2017-01-01

    It is observed that teacher candidates receiving education in the department of Computer and Instructional Technologies Education are not able to gain enough experience and knowledge in "Programming Languages" lesson. The goal of this study is to analyse the effects of web 2.0 technologies usage in programming languages lesson on the…

  1. The Australian Language Levels (ALL) Project--A Response to Curriculum Needs in Australia.

    ERIC Educational Resources Information Center

    Scarino, Angela; McKay, Penny

    Australia has a unique range of language communities and language education needs. A variety of languages is currently offered to different groups of learners through diverse programs. Language teaching may be provided through bilingual education, limited-exposure programs, or compulsory language instruction. Federal and state education agencies,…

  2. SINE_scan: an efficient tool to discover short interspersed nuclear elements (SINEs) in large-scale genomic datasets.

    PubMed

    Mao, Hongliang; Wang, Hao

    2017-03-01

    Short Interspersed Nuclear Elements (SINEs) are transposable elements (TEs) that amplify through a copy-and-paste mode via RNA intermediates. The computational identification of new SINEs are challenging because of their weak structural signals and rapid diversification in sequences. Here we report SINE_Scan, a highly efficient program to predict SINE elements in genomic DNA sequences. SINE_Scan integrates hallmark of SINE transposition, copy number and structural signals to identify a SINE element. SINE_Scan outperforms the previously published de novo SINE discovery program. It shows high sensitivity and specificity in 19 plant and animal genome assemblies, of which sizes vary from 120 Mb to 3.5 Gb. It identifies numerous new families and substantially increases the estimation of the abundance of SINEs in these genomes. The code of SINE_Scan is freely available at http://github.com/maohlzj/SINE_Scan , implemented in PERL and supported on Linux. wangh8@fudan.edu.cn. Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press.

  3. SINE_scan: an efficient tool to discover short interspersed nuclear elements (SINEs) in large-scale genomic datasets

    PubMed Central

    Mao, Hongliang

    2017-01-01

    Abstract Motivation: Short Interspersed Nuclear Elements (SINEs) are transposable elements (TEs) that amplify through a copy-and-paste mode via RNA intermediates. The computational identification of new SINEs are challenging because of their weak structural signals and rapid diversification in sequences. Results: Here we report SINE_Scan, a highly efficient program to predict SINE elements in genomic DNA sequences. SINE_Scan integrates hallmark of SINE transposition, copy number and structural signals to identify a SINE element. SINE_Scan outperforms the previously published de novo SINE discovery program. It shows high sensitivity and specificity in 19 plant and animal genome assemblies, of which sizes vary from 120 Mb to 3.5 Gb. It identifies numerous new families and substantially increases the estimation of the abundance of SINEs in these genomes. Availability and Implementation: The code of SINE_Scan is freely available at http://github.com/maohlzj/SINE_Scan, implemented in PERL and supported on Linux. Contact: wangh8@fudan.edu.cn Supplementary information: Supplementary data are available at Bioinformatics online. PMID:28062442

  4. Generation of non-genomic oligonucleotide tag sequences for RNA template-specific PCR

    PubMed Central

    Pinto, Fernando Lopes; Svensson, Håkan; Lindblad, Peter

    2006-01-01

    Background In order to overcome genomic DNA contamination in transcriptional studies, reverse template-specific polymerase chain reaction, a modification of reverse transcriptase polymerase chain reaction, is used. The possibility of using tags whose sequences are not found in the genome further improves reverse specific polymerase chain reaction experiments. Given the absence of software available to produce genome suitable tags, a simple tool to fulfill such need was developed. Results The program was developed in Perl, with separate use of the basic local alignment search tool, making the tool platform independent (known to run on Windows XP and Linux). In order to test the performance of the generated tags, several molecular experiments were performed. The results show that Tagenerator is capable of generating tags with good priming properties, which will deliberately not result in PCR amplification of genomic DNA. Conclusion The program Tagenerator is capable of generating tag sequences that combine genome absence with good priming properties for RT-PCR based experiments, circumventing the effects of genomic DNA contamination in an RNA sample. PMID:16820068

  5. A HyperCard Program for Business German.

    ERIC Educational Resources Information Center

    Paulsell, Patricia R.

    Although the use of computer-assisted language instruction software has been mainly limited to grammatical/syntactical drills, the increasing number of language professionals with programming skills is leading to the development of more sophisticated language education programs. This report describes the generation of such a program using the…

  6. Programming languages for synthetic biology.

    PubMed

    Umesh, P; Naveen, F; Rao, Chanchala Uma Maheswara; Nair, Achuthsankar S

    2010-12-01

    In the backdrop of accelerated efforts for creating synthetic organisms, the nature and scope of an ideal programming language for scripting synthetic organism in-silico has been receiving increasing attention. A few programming languages for synthetic biology capable of defining, constructing, networking, editing and delivering genome scale models of cellular processes have been recently attempted. All these represent important points in a spectrum of possibilities. This paper introduces Kera, a state of the art programming language for synthetic biology which is arguably ahead of similar languages or tools such as GEC, Antimony and GenoCAD. Kera is a full-fledged object oriented programming language which is tempered by biopart rule library named Samhita which captures the knowledge regarding the interaction of genome components and catalytic molecules. Prominent feature of the language are demonstrated through a toy example and the road map for the future development of Kera is also presented.

  7. Gestalt Therapy: Student Perceptions of Fritz Perls in "Three Approaches to Psychotherapy"

    ERIC Educational Resources Information Center

    Reilly, Joe; Jacobus, Veronica

    2009-01-01

    The "Three Approaches to Psychotherapy" ("TAP") videotape series introduces students to three major schools of psychotherapy: client-centered therapy, Gestalt therapy, and rational-emotive therapy. A sample of undergraduate students viewed the "TAP" series. The students were surveyed about their observations of…

  8. Applied Computational Chemistry for the Blind and Visually Impaired

    ERIC Educational Resources Information Center

    Wedler, Henry B.; Cohen, Sarah R.; Davis, Rebecca L.; Harrison, Jason G.; Siebert, Matthew R.; Willenbring, Dan; Hamann, Christian S.; Shaw, Jared T.; Tantillo, Dean J.

    2012-01-01

    We describe accommodations that we have made to our applied computational-theoretical chemistry laboratory to provide access for blind and visually impaired students interested in independent investigation of structure-function relationships. Our approach utilizes tactile drawings, molecular model kits, existing software, Bash and Perl scripts…

  9. Software For Least-Squares And Robust Estimation

    NASA Technical Reports Server (NTRS)

    Jeffreys, William H.; Fitzpatrick, Michael J.; Mcarthur, Barbara E.; Mccartney, James

    1990-01-01

    GAUSSFIT computer program includes full-featured programming language facilitating creation of mathematical models solving least-squares and robust-estimation problems. Programming language designed to make it easy to specify complex reduction models. Written in 100 percent C language.

  10. Learning Through Survival: An Approach to Foreign Language Teaching. A Program Description and Evaluation.

    ERIC Educational Resources Information Center

    Travers, Claudia S.; Reilly, Joseph T. M.

    A foreign travel program for eighth grade French language students from Shoreham, New York was developed to provide language speaking practice in Quebec, Canada. The program was designed to allow students to spend as much time as possible speaking the language and interacting with the people. The following "survival through speaking"…

  11. Linking Language and Culture in the Language and Cultural Program of the Lauder Institute: The French Perspective.

    ERIC Educational Resources Information Center

    Lahaeye, Marie-Noelle

    The University of Pennsylvania's Lauder Institute of Management and International Studies introduced a cultural segment into its second language program in 1986 to enable students to use language purposefully within the foreign culture. During the program's 2 years, students are exposed to eight different cultural segments taught by language…

  12. A Systematic Meta-Analytic Review of Evidence for the Effectiveness of the "Fast ForWord" Language Intervention Program

    ERIC Educational Resources Information Center

    Strong, Gemma K.; Torgerson, Carole J.; Torgerson, David; Hulme, Charles

    2011-01-01

    Background: Fast ForWord is a suite of computer-based language intervention programs designed to improve children's reading and oral language skills. The programs are based on the hypothesis that oral language difficulties often arise from a rapid auditory temporal processing deficit that compromises the development of phonological…

  13. New Dimensions in Language Training: The Dartmouth College Experiment.

    ERIC Educational Resources Information Center

    Rassias, John A.

    The expanded foreign study and foreign language programs offered at Dartmouth are examined with emphasis on the influence of Peace Corps language programs during the last half-dozen years on American college campuses. The impact of the programs at Dartmouth since 1964 is discussed in terms of: (1) a brief history of language instruction at…

  14. Uses of Technology in the Instruction of Adult English Language Learners. CAELA Network Brief

    ERIC Educational Resources Information Center

    Moore, Sarah Catherine K.

    2009-01-01

    In program year 2006-2007, 46 percent of the adults enrolled in federally funded, state-administered adult education programs in the United States were enrolled in English as a Second Language (ESL) programs. These adult English language learners represent a wide range of ages, nationalities, native languages, and English proficiency levels. In…

  15. HAL/S language specification

    NASA Technical Reports Server (NTRS)

    Newbold, P. M.

    1974-01-01

    A programming language for the flight software of the NASA space shuttle program was developed and identified as HAL/S. The language is intended to satisfy virtually all of the flight software requirements of the space shuttle. The language incorporates a wide range of features, including applications-oriented data types and organizations, real time control mechanisms, and constructs for systems programming tasks.

  16. A Multicultural Awareness Program To Improve Language and Thinking Skills to a Group of Language Deficient Preschool Students.

    ERIC Educational Resources Information Center

    Altamura, Marilyn T.

    This practicum project exposed seven preschool students with language deficiencies to multicultural experiences and strategies, resulting in improvements in both language and thinking skills. The children were included in a regular preschool program serving low-income families. The program was based on a multicultural awareness curriculum which…

  17. The Dual Language Program Planner: A Guide for Designing and Implementing Dual Language Programs.

    ERIC Educational Resources Information Center

    Howard, Elizabeth R.; Olague, Natalie; Rogers, David

    This guide offers a framework to facilitate the planning process for dual language programs, assuming at least a basic working knowledge of the central characteristics and essential features of dual language models. It provides an overview of the various models that serve linguistically diverse student populations, defining the term dual language…

  18. 25 CFR 39.131 - What is a Language Development Program?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What is a Language Development Program? 39.131 Section 39.131 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION THE INDIAN SCHOOL EQUALIZATION PROGRAM Indian School Equalization Formula Language Development Programs § 39.131 What is a...

  19. 34 CFR 658.11 - What projects and activities may a grantee conduct under this program?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... STUDIES AND FOREIGN LANGUAGE PROGRAM What Kinds of Projects Does the Secretary Assist Under This Program... program to improve undergraduate instruction in international studies and foreign languages. These include... studies and foreign languages; (b) Teaching, research, curriculum development, faculty training in the...

  20. 34 CFR 658.11 - What projects and activities may a grantee conduct under this program?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... STUDIES AND FOREIGN LANGUAGE PROGRAM What Kinds of Projects Does the Secretary Assist Under This Program... program to improve undergraduate instruction in international studies and foreign languages. These include... studies and foreign languages; (b) Teaching, research, curriculum development, faculty training in the...

  1. 34 CFR 658.11 - What projects and activities may a grantee conduct under this program?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... STUDIES AND FOREIGN LANGUAGE PROGRAM What Kinds of Projects Does the Secretary Assist Under This Program... program to improve undergraduate instruction in international studies and foreign languages. These include... studies and foreign languages; (b) Teaching, research, curriculum development, faculty training in the...

  2. The Dynamics of Language Program Direction. Issues in Language Program Direction: A Series of Annual Volumes.

    ERIC Educational Resources Information Center

    Benseler, David P., Ed.

    This collection papers begins with "Introduction: The Dynamics of Successful Leadership in Foreign Language Programs," then features the following: "The Undergraduate Program: Autonomy and Empowerment" (Wilga M. Rivers); "TA Supervision: Are We Preparing a Future Professoriate?" (Cathy Pons); "Applied Scholarship…

  3. [Union-Endicott Schools: Foreign Language Program.

    ERIC Educational Resources Information Center

    O'Connell, Raymond S.

    This brochure describing language programs to both parents and prospective high school language students in Endicott, New York focuses on developing student motivation and interest. Topics discussed include: (1) reasons for studying foreign language, (2) stages of foreign language learning, (3) course offerings, (4) homework, and (5) examinations.…

  4. Author Languages, Authoring Systems, and Their Relation to the Changing Focus of Computer-Aided Language Learning.

    ERIC Educational Resources Information Center

    Sussex, Roland

    1991-01-01

    Considers how the effectiveness of computer-assisted language learning (CALL) has been hampered by language teachers who lack programing and software engineering expertise, and explores the limitations and potential contributions of author languages, programs, and environments in increasing the range of options for language teachers who are not…

  5. More than Words, A Way of Life: Language Restoration Programs Reach beyond Tribal Colleges and Universities

    ERIC Educational Resources Information Center

    Paskus, Laura

    2013-01-01

    In North America, and worldwide, Indigenous languages are disappearing at an alarming rate. There are, however, models of success for language revitalization in immersion language programs, usually found in tribal colleges and universities. Whether the language learners are tribal college students greeting one another in their native language,…

  6. Numerical evaluation of multi-loop integrals for arbitrary kinematics with SecDec 2.0

    NASA Astrophysics Data System (ADS)

    Borowka, Sophia; Carter, Jonathon; Heinrich, Gudrun

    2013-02-01

    We present the program SecDec 2.0, which contains various new features. First, it allows the numerical evaluation of multi-loop integrals with no restriction on the kinematics. Dimensionally regulated ultraviolet and infrared singularities are isolated via sector decomposition, while threshold singularities are handled by a deformation of the integration contour in the complex plane. As an application, we present numerical results for various massive two-loop four-point diagrams. SecDec 2.0 also contains new useful features for the calculation of more general parameter integrals, related for example to phase space integrals. Program summaryProgram title: SecDec 2.0 Catalogue identifier: AEIR_v2_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEIR_v2_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 156829 No. of bytes in distributed program, including test data, etc.: 2137907 Distribution format: tar.gz Programming language: Wolfram Mathematica, Perl, Fortran/C++. Computer: From a single PC to a cluster, depending on the problem. Operating system: Unix, Linux. RAM: Depending on the complexity of the problem Classification: 4.4, 5, 11.1. Catalogue identifier of previous version: AEIR_v1_0 Journal reference of previous version: Comput. Phys. Comm. 182(2011)1566 Does the new version supersede the previous version?: Yes Nature of problem: Extraction of ultraviolet and infrared singularities from parametric integrals appearing in higher order perturbative calculations in gauge theories. Numerical integration in the presence of integrable singularities (e.g., kinematic thresholds). Solution method: Algebraic extraction of singularities in dimensional regularization using iterated sector decomposition. This leads to a Laurent series in the dimensional regularization parameter ɛ, where the coefficients are finite integrals over the unit hypercube. Those integrals are evaluated numerically by Monte Carlo integration. The integrable singularities are handled by choosing a suitable integration contour in the complex plane, in an automated way. Reasons for new version: In the previous version the calculation of multi-scale integrals was restricted to the Euclidean region. Now multi-loop integrals with arbitrary physical kinematics can be evaluated. Another major improvement is the possibility of full parallelization. Summary of revisions: No restriction on the kinematics for multi-loop integrals. The integrand can be constructed from the topological cuts of the diagram. Possibility of full parallelization. Numerical integration of multi-loop integrals written in C++ rather than Fortran. Possibility to loop over ranges of parameters. Restrictions: Depending on the complexity of the problem, limited by memory and CPU time. The restriction that multi-scale integrals could only be evaluated at Euclidean points is superseded in version 2.0. Running time: Between a few minutes and several days, depending on the complexity of the problem. Test runs provided take only seconds.

  7. Moving multiple sinks through wireless sensor networks for lifetime maximization.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Petrioli, Chiara; Carosi, Alessio; Basagni, Stefano

    2008-01-01

    Unattended sensor networks typically watch for some phenomena such as volcanic events, forest fires, pollution, or movements in animal populations. Sensors report to a collection point periodically or when they observe reportable events. When sensors are too far from the collection point to communicate directly, other sensors relay messages for them. If the collection point location is static, sensor nodes that are closer to the collection point relay far more messages than those on the periphery. Assuming all sensor nodes have roughly the same capabilities, those with high relay burden experience battery failure much faster than the rest of themore » network. However, since their death disconnects the live nodes from the collection point, the whole network is then dead. We consider the problem of moving a set of collectors (sinks) through a wireless sensor network to balance the energy used for relaying messages, maximizing the lifetime of the network. We show how to compute an upper bound on the lifetime for any instance using linear and integer programming. We present a centralized heuristic that produces sink movement schedules that produce network lifetimes within 1.4% of the upper bound for realistic settings. We also present a distributed heuristic that produces lifetimes at most 25:3% below the upper bound. More specifically, we formulate a linear program (LP) that is a relaxation of the scheduling problem. The variables are naturally continuous, but the LP relaxes some constraints. The LP has an exponential number of constraints, but we can satisfy them all by enforcing only a polynomial number using a separation algorithm. This separation algorithm is a p-median facility location problem, which we can solve efficiently in practice for huge instances using integer programming technology. This LP selects a set of good sensor configurations. Given the solution to the LP, we can find a feasible schedule by selecting a subset of these configurations, ordering them via a traveling salesman heuristic, and computing feasible transitions using matching algorithms. This algorithm assumes sinks can get a schedule from a central server or a leader sink. If the network owner prefers the sinks make independent decisions, they can use our distributed heuristic. In this heuristic, sinks maintain estimates of the energy distribution in the network and move greedily (with some coordination) based on local search. This application uses the new SUCASA (Solver Utility for Customization with Automatic Symbol Access) facility within the PICO (Parallel Integer and Combinatorial Optimizer) integer programming solver system. SUCASA allows rapid development of customized math programming (search-based) solvers using a problem's natural multidimensional representation. In this case, SUCASA also significantly improves runtime compared to implementations in the ampl math programming language or in perl.« less

  8. Real-Time Multiprocessor Programming Language (RTMPL) user's manual

    NASA Technical Reports Server (NTRS)

    Arpasi, D. J.

    1985-01-01

    A real-time multiprocessor programming language (RTMPL) has been developed to provide for high-order programming of real-time simulations on systems of distributed computers. RTMPL is a structured, engineering-oriented language. The RTMPL utility supports a variety of multiprocessor configurations and types by generating assembly language programs according to user-specified targeting information. Many programming functions are assumed by the utility (e.g., data transfer and scaling) to reduce the programming chore. This manual describes RTMPL from a user's viewpoint. Source generation, applications, utility operation, and utility output are detailed. An example simulation is generated to illustrate many RTMPL features.

  9. Should bilingual children learn reading in two languages at the same time or in sequence?

    PubMed Central

    Berens, Melody S.; Kovelman, Ioulia; Petitto, Laura-Ann

    2013-01-01

    Is it best to learn reading in two languages simultaneously or sequentially? We observed 2nd and 3rd grade children in two-way dual-language learning contexts: (i) 50:50 or Simultaneous dual-language (two languages within same developmental period) and (ii) 90:10 or Sequential dual-language (one language, followed gradually by the other). They were compared to matched monolingual English-only children in single-language English schools. Bilinguals (home language was Spanish only, English-only, or Spanish and English in dual-language schools), were tested in both languages, and monolingual children were tested in English using standardized reading and language tasks. Bilinguals in 50:50 programs performed better than bilinguals in 90:10 programs on English Irregular Words and Passage Comprehension tasks, suggesting language and reading facilitation for underlying grammatical class and linguistic structure analyses. By contrast, bilinguals in 90:10 programs performed better than bilinguals in the 50:50 programs on English Phonological Awareness and Reading Decoding tasks, suggesting language and reading facilitation for surface phonological regularity analysis. Notably, children from English-only homes in dual-language learning contexts performed equally well, or better than, children from monolingual English-only homes in single-language learning contexts. Overall, the findings provide tantalizing evidence that dual-language learning during the same developmental period may provide bilingual reading advantages. PMID:23794952

  10. The Advantages and Disadvantages of Computer Technology in Second Language Acquisition

    ERIC Educational Resources Information Center

    Lai, Cheng-Chieh; Kritsonis, William Allan

    2006-01-01

    The purpose of this article is to discuss the advantages and disadvantages of computer technology and Computer Assisted Language Learning (CALL) programs for current second language learning. According to the National Clearinghouse for English Language Acquisition & Language Instruction Educational Programs' report (2002), more than nine million…

  11. Online Collaborative Communities of Learning for Pre-Service Teachers of Languages

    ERIC Educational Resources Information Center

    Morgan, Anne-Marie

    2015-01-01

    University programs for preparing preservice teachers of languages for teaching in schools generally involve generic pedagogy, methodology, curriculum, programming and issues foci, that provide a bridge between the study of languages (or recognition of existing language proficiency) and the teaching of languages. There is much territory to cover…

  12. A Whole Language Flight Plan: An Interview with Three Teachers.

    ERIC Educational Resources Information Center

    Griffith, Priscilla L.; Klesius, Janell

    1990-01-01

    Provides suggestions to teachers planning to implement a whole language program, based on interviews with three whole language teachers. Focuses on support for the whole language program; decisions about curriculum and evaluation; development of vocabulary and comprehension; strengths and weaknesses of the whole language approach; and preparation…

  13. Programming parallel architectures: The BLAZE family of languages

    NASA Technical Reports Server (NTRS)

    Mehrotra, Piyush

    1988-01-01

    Programming multiprocessor architectures is a critical research issue. An overview is given of the various approaches to programming these architectures that are currently being explored. It is argued that two of these approaches, interactive programming environments and functional parallel languages, are particularly attractive since they remove much of the burden of exploiting parallel architectures from the user. Also described is recent work by the author in the design of parallel languages. Research on languages for both shared and nonshared memory multiprocessors is described, as well as the relations of this work to other current language research projects.

  14. ABINIT: First-principles approach to material and nanosystem properties

    NASA Astrophysics Data System (ADS)

    Gonze, X.; Amadon, B.; Anglade, P.-M.; Beuken, J.-M.; Bottin, F.; Boulanger, P.; Bruneval, F.; Caliste, D.; Caracas, R.; Côté, M.; Deutsch, T.; Genovese, L.; Ghosez, Ph.; Giantomassi, M.; Goedecker, S.; Hamann, D. R.; Hermet, P.; Jollet, F.; Jomard, G.; Leroux, S.; Mancini, M.; Mazevet, S.; Oliveira, M. J. T.; Onida, G.; Pouillon, Y.; Rangel, T.; Rignanese, G.-M.; Sangalli, D.; Shaltaf, R.; Torrent, M.; Verstraete, M. J.; Zerah, G.; Zwanziger, J. W.

    2009-12-01

    ABINIT [ http://www.abinit.org] allows one to study, from first-principles, systems made of electrons and nuclei (e.g. periodic solids, molecules, nanostructures, etc.), on the basis of Density-Functional Theory (DFT) and Many-Body Perturbation Theory. Beyond the computation of the total energy, charge density and electronic structure of such systems, ABINIT also implements many dynamical, dielectric, thermodynamical, mechanical, or electronic properties, at different levels of approximation. The present paper provides an exhaustive account of the capabilities of ABINIT. It should be helpful to scientists that are not familiarized with ABINIT, as well as to already regular users. First, we give a broad overview of ABINIT, including the list of the capabilities and how to access them. Then, we present in more details the recent, advanced, developments of ABINIT, with adequate references to the underlying theory, as well as the relevant input variables, tests and, if available, ABINIT tutorials. Program summaryProgram title: ABINIT Catalogue identifier: AEEU_v1_0 Distribution format: tar.gz Journal reference: Comput. Phys. Comm. Programming language: Fortran95, PERL scripts, Python scripts Computer: All systems with a Fortran95 compiler Operating system: All systems with a Fortran95 compiler Has the code been vectorized or parallelized?: Sequential, or parallel with proven speed-up up to one thousand processors. RAM: Ranges from a few Mbytes to several hundred Gbytes, depending on the input file. Classification: 7.3, 7.8 External routines: (all optional) BigDFT [1], ETSF IO [2], libxc [3], NetCDF [4], MPI [5], Wannier90 [6] Nature of problem: This package has the purpose of computing accurately material and nanostructure properties: electronic structure, bond lengths, bond angles, primitive cell size, cohesive energy, dielectric properties, vibrational properties, elastic properties, optical properties, magnetic properties, non-linear couplings, electronic and vibrational lifetimes, etc. Solution method: Software application based on Density-Functional Theory and Many-Body Perturbation Theory, pseudopotentials, with planewaves, Projector-Augmented Waves (PAW) or wavelets as basis functions. Running time: From less than one second for the simplest tests, to several weeks. The vast majority of the >600 provided tests run in less than 30 seconds. References:[1] http://inac.cea.fr/LSim/BigDFT. [2] http://etsf.eu/index.php?page=standardization. [3] http://www.tddft.org/programs/octopus/wiki/index.php/Libxc. [4] http://www.unidata.ucar.edu/software/netcdf. [5] http://en.wikipedia.org/wiki/MessagePassingInterface. [6] http://www.wannier.org.

  15. Automating Visualization Service Generation with the WATT Compiler

    NASA Astrophysics Data System (ADS)

    Bollig, E. F.; Lyness, M. D.; Erlebacher, G.; Yuen, D. A.

    2007-12-01

    As tasks and workflows become increasingly complex, software developers are devoting increasing attention to automation tools. Among many examples, the Automator tool from Apple collects components of a workflow into a single script, with very little effort on the part of the user. Tasks are most often described as a series of instructions. The granularity of the tasks dictates the tools to use. Compilers translate fine-grained instructions to assembler code, while scripting languages (ruby, perl) are used to describe a series of tasks at a higher level. Compilers can also be viewed as transformational tools: a cross-compiler can translate executable code written on one computer to assembler code understood on another, while transformational tools can translate from one high-level language to another. We are interested in creating visualization web services automatically, starting from stand-alone VTK (Visualization Toolkit) code written in Tcl. To this end, using the OCaml programming language, we have developed a compiler that translates Tcl into C++, including all the stubs, classes and methods to interface with gSOAP, a C++ implementation of the Soap 1.1/1.2 protocols. This compiler, referred to as the Web Automation and Translation Toolkit (WATT), is the first step towards automated creation of specialized visualization web services without input from the user. The WATT compiler seeks to automate all aspects of web service generation, including the transport layer, the division of labor and the details related to interface generation. The WATT compiler is part of ongoing efforts within the NSF funded VLab consortium [1] to facilitate and automate time-consuming tasks for the science related to understanding planetary materials. Through examples of services produced by WATT for the VLab portal, we will illustrate features, limitations and the improvements necessary to achieve the ultimate goal of complete and transparent automation in the generation of web services. In particular, we will detail the generation of a charge density visualization service applicable to output from the quantum calculations of the VLab computation workflows, plus another service for mantle convection visualization. We also discuss WATT-LIVE [2], a web-based interface that allows users to interact with WATT. With WATT-LIVE users submit Tcl code, retrieve its C++ translation with various files and scripts necessary to locally install the tailor-made web service, or launch the service for a limited session on our test server. This work is supported by NSF through the ITR grant NSF-0426867. [1] Virtual Laboratory for Earth and Planetary Materials, http://vlab.msi.umn.edu, September 2007. [2] WATT-LIVE website, http://vlab2.scs.fsu.edu/watt-live, September 2007.

  16. Defense Contracting: Actions Needed to Explore Additional Opportunities to Gain Efficiencies in Acquiring Foreign Language Support

    DTIC Science & Technology

    2013-02-25

    Directive 5160.41E, Defense Language Program . 10GAO-11-456. Page 5 GAO-13-251R Defense Contracting types of foreign language support that DOD has acquired...Language Transformation Roadmap, (January 2005), and Department of Defense Directive 5160.41E, Defense Language Program . Page 15 GAO-13-251R Defense...examines the use of public funds; evaluates federal programs and policies; and provides analyses, recommendations, and other assistance to help

  17. The PlusCal Algorithm Language

    NASA Astrophysics Data System (ADS)

    Lamport, Leslie

    Algorithms are different from programs and should not be described with programming languages. The only simple alternative to programming languages has been pseudo-code. PlusCal is an algorithm language that can be used right now to replace pseudo-code, for both sequential and concurrent algorithms. It is based on the TLA + specification language, and a PlusCal algorithm is automatically translated to a TLA + specification that can be checked with the TLC model checker and reasoned about formally.

  18. A Debate over the Teaching of a Legacy Programming Language in an Information Technology (IT) Program

    ERIC Educational Resources Information Center

    Ali, Azad; Smith, David

    2014-01-01

    This paper presents a debate between two faculty members regarding the teaching of the legacy programming course (COBOL) in a Computer Science (CS) program. Among the two faculty members, one calls for the continuation of teaching this language and the other calls for replacing it with another modern language. Although CS programs are notorious…

  19. EasyModeller: A graphical interface to MODELLER

    PubMed Central

    2010-01-01

    Background MODELLER is a program for automated protein Homology Modeling. It is one of the most widely used tool for homology or comparative modeling of protein three-dimensional structures, but most users find it a bit difficult to start with MODELLER as it is command line based and requires knowledge of basic Python scripting to use it efficiently. Findings The study was designed with an aim to develop of "EasyModeller" tool as a frontend graphical interface to MODELLER using Perl/Tk, which can be used as a standalone tool in windows platform with MODELLER and Python preinstalled. It helps inexperienced users to perform modeling, assessment, visualization, and optimization of protein models in a simple and straightforward way. Conclusion EasyModeller provides a graphical straight forward interface and functions as a stand-alone tool which can be used in a standard personal computer with Microsoft Windows as the operating system. PMID:20712861

  20. Suggestions for Improvement of User Access to GOCE L2 Data

    NASA Astrophysics Data System (ADS)

    Tscherning, C. C.

    2011-07-01

    ESA's has required that most GOCE L2 products are delivered in XML format. This creates difficulties for the users because a Parser written in Perl is needed to convert the files to files without XML tags. However several products, such as the coefficients of spherical harmonic coefficients are made available on standard form through the International Center for Global Gravity Field Models. The variance-covariance information for the gravity field models is only available without XML tags. It is suggested that all XML products are made available in the Virtual Data Archive as files without tags. This will besides making the data directly usable by a FORTRAN program also reduce the size (storage requirements) of the product to about 30 %. A further reduction of used storage should be made by tuning the number of digits for the individual quantities in the products, so that it corresponds to the actual number of significant digits.

  1. Replacement Sequence of Events Generator

    NASA Technical Reports Server (NTRS)

    Fisher, Forest; Gladden, Daniel Wenkert Roy; Khanampompan, Teerpat

    2008-01-01

    The soeWINDOW program automates the generation of an ITAR (International Traffic in Arms Regulations)-compliant sub-RSOE (Replacement Sequence of Events) by extracting a specified temporal window from an RSOE while maintaining page header information. RSOEs contain a significant amount of information that is not ITAR-compliant, yet that foreign partners need to see for command details to their instrument, as well as the surrounding commands that provide context for validation. soeWINDOW can serve as an example of how command support products can be made ITAR-compliant for future missions. This software is a Perl script intended for use in the mission operations UNIX environment. It is designed for use to support the MRO (Mars Reconnaissance Orbiter) instrument team. The tool also provides automated DOM (Distributed Object Manager) storage into the special ITAR-okay DOM collection, and can be used for creating focused RSOEs for product review by any of the MRO teams.

  2. Ferrenberg Swendsen Analysis of LLNL and NYBlue BG/L p4rhms Data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Soltz, R

    2007-12-05

    These results are from the continuing Lattice Quantum Chromodynamics runs on BG/L. These results are from the Ferrenberg-Swendsen analysis [?] of the combined data from LLNL and NYBlue BG/L runs for 32{sup 3} x 8 runs with the p4rhmc v2.0 QMP-MPI.X (semi-optimized p4 code using qmp over mpi). The jobs include beta values ranging from 3.525 to 3.535 with an alternate analysis extending to 3.540. The NYBlue data sets are from 9k trajectories from Oct 2007, and the LLNL data are from two independent streams of {approx}5k each, taking from the July 2007 runs. The following outputs are produced bymore » the fs-2+1-chiub.c program. All outputs have had checksums produced by addCks.pl and checked by the checkCks.pl perl script after scanning.« less

  3. Mobile Language Study

    DTIC Science & Technology

    2003-08-18

    Language Study 5c. PROGRAM ELEMENT NUMBER 5d. PROJECT NUMBER 5d. TASK NUMBER 6. AUTHOR(S) Professor Mads Dam, Pablo Giambiagi 5e...Standard Form 298 (Rev. 8/98) Prescribed by ANSI Std. Z39-18 SPC 01-4025 Mobile Language Study Final...smart card applications. Smart cards can be programmed using general-purpose languages ; but because of their limited resources, smart card programs

  4. A Program Evaluation of the Language Lab™: Response to Intervention Program for Teaching Grammar, Vocabulary, and Storytelling

    ERIC Educational Resources Information Center

    Wiechmann, JoAnn; Richardson, Martha; Jones, Don

    2014-01-01

    This program evaluation study addressed the struggle of local elementary school speech-language pathologists (SLPs) in a school district to provide evidence-based intervention in language for students below grade level as required by the U.S. Department of Education. Recently, Language Lab™ was published to address the needs of oral language…

  5. Japan-U.S. Joint Ventures in Higher Education: Language Education in an Uncertain Future.

    ERIC Educational Resources Information Center

    Clayton, Thomas

    1991-01-01

    Examines Japanese-U.S. joint venture language or U.S.-style education programs in Japan. These programs offer language and cultural education classes for those interested in English and for students who have failed in the Japanese education system. Problems facing these programs and the need to explore new, English-language education markets are…

  6. Algunos aspectos sicolinguisticos de la Instruccion Programada en el laboratorio de idiomas (Some Psycholinguistic Aspects of Programed Instruction in the Language Laboratory).

    ERIC Educational Resources Information Center

    Monteverde G., Luisa

    1971-01-01

    This paper presents ideas on using programed instruction in the language laboratory for second language learning. Linear programing is more suited to language instruction than is branching, because the former more easily allows comparison between the students' and teachers' solutions and is technically less complicated and less expensive to…

  7. C Language Integrated Production System, Ada Version

    NASA Technical Reports Server (NTRS)

    Culbert, Chris; Riley, Gary; Savely, Robert T.; Melebeck, Clovis J.; White, Wesley A.; Mcgregor, Terry L.; Ferguson, Melisa; Razavipour, Reza

    1992-01-01

    CLIPS/Ada provides capabilities of CLIPS v4.3 but uses Ada as source language for CLIPS executable code. Implements forward-chaining rule-based language. Program contains inference engine and language syntax providing framework for construction of expert-system program. Also includes features for debugging application program. Based on Rete algorithm which provides efficient method for performing repeated matching of patterns. Written in Ada.

  8. Beyond Course Availability: An Investigation into Order and Concurrency Effects of Undergraduate Programming Courses on Learning.

    ERIC Educational Resources Information Center

    Urbaczewski, Andrew; Urbaczewski, Lise

    The objective of this study was to find the answers to two primary research questions: "Do students learn programming languages better when they are offered in a particular order, such as 4th generation languages before 3rd generation languages?"; and "Do students learn programming languages better when they are taken in separate semesters as…

  9. Implementing Two-Way Dual-Language Immersion Programs: Classroom Insights from an Urban District. Research Brief. RB-9921

    ERIC Educational Resources Information Center

    Li, Jennifer J.; Steele, Jennifer L.; Slater, Robert; Bacon, Michael; Miller, Trey

    2016-01-01

    Dual-language immersion programs--in which students learn core subjects (language arts, math, science, and social studies) in both English and a "partner" language--have been gaining in popularity across the United States. Such programs may use a "two-way model," in which roughly half the students are native speakers of the…

  10. Language Interference and Language Learning Techniques Transfer in L2 and L3 Immersion Programs.

    ERIC Educational Resources Information Center

    Aronin, Larissa; Toubkin, Lynne

    2002-01-01

    Examines the relationships between the first (L1), second (L2), and third (L3) language in immersion programs for Russian-speaking students in Israel. Two parallel and similar immersion programs, which were carried out for the same population, but with different target languages (L2 Hebrew and L3 English), are described. Presents tentative…

  11. Race, Power, and Equity in a Multiethnic Urban Elementary School with a Dual-Language "Strand" Program

    ERIC Educational Resources Information Center

    Palmer, Deborah

    2010-01-01

    Dual-language education is often lauded for providing high-caliber bilingual instruction in an integrated classroom. This is complicated, however, when a dual-language program does not include all members of a school community. This article examines a "strand" dual-language program that attracts middle-class white students to a predominantly black…

  12. Achieving Academic Control in Two Languages: Drawing on the Psychology of Language Learning in Considering the Past, the Present, and Prospects for the Future

    ERIC Educational Resources Information Center

    Cohen, Andrew D.

    2015-01-01

    This paper first considers what it means to become truly proficient in a language other than the native one. It then looks briefly at the evolution of dual language programs. Next, it focuses on the issue of whether the first language (L1) or the second language (L2) serves as the language of mediation. Other dual language program issues are then…

  13. The Value of Foreign Language in Business.

    ERIC Educational Resources Information Center

    Stebinger, Arnold

    The University of South Carolina's Master's Program in International Business began in June 1974, with 43 students studying German and Spanish. The program began with a 9-week intensive language learning program, followed by a nine-month unified business program, with language instruction twice a week; six weeks of area study concentrating on the…

  14. Using Microcomputer Word Processors for Foreign Languages.

    ERIC Educational Resources Information Center

    Smith, Kim L.

    1984-01-01

    Describes the programs and modifications needed to do word processing using foreign language characters. One such program, Screenwriter, uses soft character sets -- character sets which can be designed by the program user. This program has a word processing power combined with a foreign language capability that would allow any person to work with…

  15. Language Programs at Villababel High: Rethinking Ideologies of Social Inclusion

    ERIC Educational Resources Information Center

    Mijares, Laura; Relano Pastor, Ana M.

    2011-01-01

    This article explores language ideologies underlying two language programs implemented in one secondary school in Madrid (Spain). The Spanish for newcomers immersion program ("Aula de Enlace") is aimed at immigrant origin students who do not know or have a poor command of Spanish; and the Spanish-English bilingual program targets…

  16. Knowledge Intensive Programming: A New Educational Computing Environment.

    ERIC Educational Resources Information Center

    Seidman, Robert H.

    1990-01-01

    Comparison of the process of problem solving using a conventional procedural computer programing language (e.g., BASIC, Logo, Pascal), with the process when using a logic programing language (i.e., Prolog), focuses on the potential of the two types of programing languages to facilitate the transfer of problem-solving skills, cognitive development,…

  17. ICCE/ICCAI 2000 Full & Short Papers (Intelligent Tutoring Systems).

    ERIC Educational Resources Information Center

    2000

    This document contains the full and short papers on intelligent tutoring systems (ITS) from ICCE/ICCAI 2000 (International Conference on Computers in Education/International Conference on Computer-Assisted Instruction) covering the following topics: a framework for Internet-based distributed learning; a fuzzy-based assessment for the Perl tutoring…

  18. Disabling Fictions: Institutionalized Delimitations of Revision.

    ERIC Educational Resources Information Center

    Carroll, Jeffrey

    1989-01-01

    Examines three contemporary taxonomies of revision as proposed by Wallace Hildick, Lester Faigley and Stephen Witte, and Sondra Perl. Uses literary and cultural theory to bridge the gap between these theories and students' revision practices. Argues that while revision may be prescriptive, it must also be subordinate to the writer's intentions and…

  19. Client Good Moments: An Intensive Analysis of a Single Session.

    ERIC Educational Resources Information Center

    Stalikas, Anastassios; Fitzpatrick, Marilyn

    1995-01-01

    An intensive analysis of a single counseling session conducted by Fritz Perls was carried out to examine relationships among client experiencing level, client strength of feeling, counselor interventions, and client good moments. The possibility that positive therapeutic outcome is related to the accretion of good moments is discussed. (JBJ)

  20. Leading System-Wide Improvement

    ERIC Educational Resources Information Center

    Harris, Alma

    2012-01-01

    Around the world there is a preoccupation with improving the performance of schools and school systems. Comparisons made between countries through PISA and PERLs have led to a preoccupation, and in some cases, an obsession, with securing a high position in the international league tables. The minds of policy-makers and politicians alike are…

  1. Cognitive characteristics of learning Java, an object-oriented programming language

    NASA Astrophysics Data System (ADS)

    White, Garry Lynn

    Industry and Academia are moving from procedural programming languages (e.g., COBOL) to object-oriented programming languages, such as Java for the Internet. Past studies in the cognitive aspects of programming have focused primarily on procedural programming languages. Some of the languages used have been Pascal, C, Basic, FORTAN, and COBOL. Object-oriented programming (OOP) represents a new paradigm for computing. Industry is finding that programmers are having difficulty shifting to this new programming paradigm. This instruction in OOP is currently starting in colleges and universities across the country. What are the cognitive aspects for this new OOP language Java? When is a student developmentally ready to handle the cognitive characteristics of the OOP language Java? Which cognitive teaching style is best for this OOP language Java? Questions such as the aforementioned are the focus of this research Such research is needed to improve understanding of the learning process and identify students' difficulties with OOP methods. This can enhance academic teaching and industry training (Scholtz, 1993; Sheetz, 1997; Rosson, 1990). Cognitive development as measured by the Propositional Logic Test, cognitive style as measured by the Hemispheric Mode Indicator, and physical hemispheric dominance as measured by a self-report survey were obtained from thirty-six university students studying Java programming. Findings reveal that physical hemispheric dominance is unrelated to cognitive and programming language variables. However, both procedural and object oriented programming require Piaget's formal operation cognitive level as indicated by the Propositional Logic Test. This is consistent with prior research A new finding is that object oriented programming also requires formal operation cognitive level. Another new finding is that object oriented programming appears to be unrelated to hemispheric cognitive style as indicated by the Hemispheric Mode Indicator (HMI). This research suggests that object oriented programming is hemispheric thinking style friendly, while procedural programming is left hemispheric cognitive style. The conclusion is that cognitive characteristics are not the cause for the difficulty in shifting from procedural to this new programming paradigm of object oriented programming. An alternative possibility to the difficulty is proactive interference. Prior learning of procedural programming makes it harder to learning object oriented programming. Further research is needed to determine if proactive interference is the cause for the difficulty in shifting from procedural programming to object oriented programming.

  2. A Proposal for a CA-Integrated English Language Teacher Education Program in Turkey

    ERIC Educational Resources Information Center

    Sert, Olcay

    2010-01-01

    This study proposes a comprehensive framework for a Conversation Analysis (CA) informed English language teacher education program in Turkey. By reviewing recent studies in CA, Critical Reflective Practice, Teacher Language Awareness and language teacher education in general; the author calls for a more effective language teacher education program…

  3. Language Training for Trainable Mentally Retarded Children: ITPA, Peabody, and Distar Techniques.

    ERIC Educational Resources Information Center

    Leiss, Robert H.; Proger, Barton B.

    To determine the most effective language training activities for trainable mentally retarded (TMR) children, the variables of degree of previous language training, IQ, Peabody language treatment program versus Distar language treatment program, pretest versus posttest, and sex were examined with 122 TMR Ss (7 to 14 years old). Results of the…

  4. Language and Man: An Exploratory Foreign-Language Program for Grade Six.

    ERIC Educational Resources Information Center

    Bartos, Marilyn; And Others

    This curriculum guide presents a program introducing sixth-grade children to the study of language, of languages other than English, and specifically of French. An initial section includes a variety of activities designed to interest students in the study of language, its peculiarties, complexities, and importance in life. Prior to the first…

  5. Teaching English as a Foreign Language in Primary School. Case Studies in TESOL Practice Series

    ERIC Educational Resources Information Center

    McCloskey, Mary Lou, Ed.; Orr, Janet, Ed.; Dolitsky, Marlene, Ed.

    2006-01-01

    Although language specialists do not always agree about the best age at which to introduce English language instruction, policy changes are increasingly mandating earlier introduction of English in foreign language (EFL) settings worldwide. In this volume, language educators and program implementers from various countries describe programs and…

  6. A Case Study of Dual Language Program Administrators: The Teachers We Need

    ERIC Educational Resources Information Center

    Lachance, Joan R.

    2017-01-01

    In support of growing numbers of dual language programs nation-wide, dual language school administrators seek to find teachers who are specifically prepared to work with dual language learners for additive biliteracy. For this research the author utilized a case study design to explore practicing dual language administrators' perspectives…

  7. Programming languages for circuit design.

    PubMed

    Pedersen, Michael; Yordanov, Boyan

    2015-01-01

    This chapter provides an overview of a programming language for Genetic Engineering of Cells (GEC). A GEC program specifies a genetic circuit at a high level of abstraction through constraints on otherwise unspecified DNA parts. The GEC compiler then selects parts which satisfy the constraints from a given parts database. GEC further provides more conventional programming language constructs for abstraction, e.g., through modularity. The GEC language and compiler is available through a Web tool which also provides functionality, e.g., for simulation of designed circuits.

  8. 76 FR 18538 - Applications for New Awards; National Professional Development Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-04

    ... DEPARTMENT OF EDUCATION [CFDA 84.195N] Applications for New Awards; National Professional Development Program AGENCY: Office of English Language Acquisition, Language Enhancement, and Academic... Language Acquisition, Language Enhancement and Academic Achievement for Limited English Proficient Students...

  9. A comparative study of programming languages for next-generation astrodynamics systems

    NASA Astrophysics Data System (ADS)

    Eichhorn, Helge; Cano, Juan Luis; McLean, Frazer; Anderl, Reiner

    2018-03-01

    Due to the computationally intensive nature of astrodynamics tasks, astrodynamicists have relied on compiled programming languages such as Fortran for the development of astrodynamics software. Interpreted languages such as Python, on the other hand, offer higher flexibility and development speed thereby increasing the productivity of the programmer. While interpreted languages are generally slower than compiled languages, recent developments such as just-in-time (JIT) compilers or transpilers have been able to close this speed gap significantly. Another important factor for the usefulness of a programming language is its wider ecosystem which consists of the available open-source packages and development tools such as integrated development environments or debuggers. This study compares three compiled languages and three interpreted languages, which were selected based on their popularity within the scientific programming community and technical merit. The three compiled candidate languages are Fortran, C++, and Java. Python, Matlab, and Julia were selected as the interpreted candidate languages. All six languages are assessed and compared to each other based on their features, performance, and ease-of-use through the implementation of idiomatic solutions to classical astrodynamics problems. We show that compiled languages still provide the best performance for astrodynamics applications, but JIT-compiled dynamic languages have reached a competitive level of speed and offer an attractive compromise between numerical performance and programmer productivity.

  10. 25 CFR 39.136 - What is the WSU for Language Development programs?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What is the WSU for Language Development programs? 39.136 Section 39.136 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION THE INDIAN SCHOOL EQUALIZATION PROGRAM Indian School Equalization Formula Language Development Programs § 39.136 What is the WSU...

  11. Standing Strong: Maloney Interdistrict Magnet School Japanese Language and Culture Program

    ERIC Educational Resources Information Center

    Haxhi, Jessica; Yamashita-Iverson, Kazumi

    2009-01-01

    Maloney Interdistrict Magnet School (MIMS) is the only elementary school in Waterbury that has a world language program and is one of only two elementary Japanese programs in Connecticut. In the past 15 years, more than 1500 students have participated in its Japanese Language and Culture (JLC) Program in grades Prekindergarten through 5th. The JLC…

  12. Pre-Service Teachers' Uses of and Barriers from Adopting Computer-Assisted Language Learning (CALL) Programs

    ERIC Educational Resources Information Center

    Samani, Ebrahim; Baki, Roselan; Razali, Abu Bakar

    2014-01-01

    Success in implementation of computer-assisted language learning (CALL) programs depends on the teachers' understanding of the roles of CALL programs in education. Consequently, it is also important to understand the barriers teachers face in the use of computer-assisted language learning (CALL) programs. The current study was conducted on 14…

  13. How the strengths of Lisp-family languages facilitate building complex and flexible bioinformatics applications.

    PubMed

    Khomtchouk, Bohdan B; Weitz, Edmund; Karp, Peter D; Wahlestedt, Claes

    2018-05-01

    We present a rationale for expanding the presence of the Lisp family of programming languages in bioinformatics and computational biology research. Put simply, Lisp-family languages enable programmers to more quickly write programs that run faster than in other languages. Languages such as Common Lisp, Scheme and Clojure facilitate the creation of powerful and flexible software that is required for complex and rapidly evolving domains like biology. We will point out several important key features that distinguish languages of the Lisp family from other programming languages, and we will explain how these features can aid researchers in becoming more productive and creating better code. We will also show how these features make these languages ideal tools for artificial intelligence and machine learning applications. We will specifically stress the advantages of domain-specific languages (DSLs): languages that are specialized to a particular area, and thus not only facilitate easier research problem formulation, but also aid in the establishment of standards and best programming practices as applied to the specific research field at hand. DSLs are particularly easy to build in Common Lisp, the most comprehensive Lisp dialect, which is commonly referred to as the 'programmable programming language'. We are convinced that Lisp grants programmers unprecedented power to build increasingly sophisticated artificial intelligence systems that may ultimately transform machine learning and artificial intelligence research in bioinformatics and computational biology.

  14. Adding Concrete Syntax to a Prolog-Based Program Synthesis System

    NASA Technical Reports Server (NTRS)

    Fischer, Bernd; Visser, Eelco

    2004-01-01

    Program generation and transformation systems work on two language levels, the object-level (i e., the language of the manipulated programs), and the meta-level (i.e., the implementation language of the system itself). The meta-level representations of object-level program fragments are usually built in an essentially syntax-free fashion using the operations provided by the meta-language. However, syntax matters and a large conceptual distance between the two languages makes it difficult to maintain and extend such systems. Here we describe how an existing Prolog-based system can gradually be retrofitted with concrete object-level syntax, thus shrinking this distance.

  15. Advanced software development workstation. Engineering scripting language graphical editor: DRAFT design document

    NASA Technical Reports Server (NTRS)

    1991-01-01

    The Engineering Scripting Language (ESL) is a language designed to allow nonprogramming users to write Higher Order Language (HOL) programs by drawing directed graphs to represent the program and having the system generate the corresponding program in HOL. The ESL system supports user generation of HOL programs through the manipulation of directed graphs. The components of this graphs (nodes, ports, and connectors) are objects each of which has its own properties and property values. The purpose of the ESL graphical editor is to allow the user to create or edit graph objects which represent programs.

  16. An experimental comparative analyse between three low capacity PLCs

    NASA Astrophysics Data System (ADS)

    Popa, G. N.; Diniş, C. M.; lagăr, A.; Popa, I.

    2017-01-01

    PLCs are used increasingly more often in industrial applications and beyond. PLCs from different companies involved different programming languages. Some of the PLCs can be programmed in all languages, while others do not. For three types of PLCs was made an application for a traffic light with priority. PLCs usually have a general and a special set of instructions that only some of these are found from a PLC to another. Programs were made with specific instruction set of respectively PLC. The programs were carried out in three languages. For a case study, it makes a comparative analysis between three programming languages.

  17. Runtime Verification of C Programs

    NASA Technical Reports Server (NTRS)

    Havelund, Klaus

    2008-01-01

    We present in this paper a framework, RMOR, for monitoring the execution of C programs against state machines, expressed in a textual (nongraphical) format in files separate from the program. The state machine language has been inspired by a graphical state machine language RCAT recently developed at the Jet Propulsion Laboratory, as an alternative to using Linear Temporal Logic (LTL) for requirements capture. Transitions between states are labeled with abstract event names and Boolean expressions over such. The abstract events are connected to code fragments using an aspect-oriented pointcut language similar to ASPECTJ's or ASPECTC's pointcut language. The system is implemented in the C analysis and transformation package CIL, and is programmed in OCAML, the implementation language of CIL. The work is closely related to the notion of stateful aspects within aspect-oriented programming, where pointcut languages are extended with temporal assertions over the execution trace.

  18. Processing sequence annotation data using the Lua programming language.

    PubMed

    Ueno, Yutaka; Arita, Masanori; Kumagai, Toshitaka; Asai, Kiyoshi

    2003-01-01

    The data processing language in a graphical software tool that manages sequence annotation data from genome databases should provide flexible functions for the tasks in molecular biology research. Among currently available languages we adopted the Lua programming language. It fulfills our requirements to perform computational tasks for sequence map layouts, i.e. the handling of data containers, symbolic reference to data, and a simple programming syntax. Upon importing a foreign file, the original data are first decomposed in the Lua language while maintaining the original data schema. The converted data are parsed by the Lua interpreter and the contents are stored in our data warehouse. Then, portions of annotations are selected and arranged into our catalog format to be depicted on the sequence map. Our sequence visualization program was successfully implemented, embedding the Lua language for processing of annotation data and layout script. The program is available at http://staff.aist.go.jp/yutaka.ueno/guppy/.

  19. CBS Genome Atlas Database: a dynamic storage for bioinformatic results and sequence data.

    PubMed

    Hallin, Peter F; Ussery, David W

    2004-12-12

    Currently, new bacterial genomes are being published on a monthly basis. With the growing amount of genome sequence data, there is a demand for a flexible and easy-to-maintain structure for storing sequence data and results from bioinformatic analysis. More than 150 sequenced bacterial genomes are now available, and comparisons of properties for taxonomically similar organisms are not readily available to many biologists. In addition to the most basic information, such as AT content, chromosome length, tRNA count and rRNA count, a large number of more complex calculations are needed to perform detailed comparative genomics. DNA structural calculations like curvature and stacking energy, DNA compositions like base skews, oligo skews and repeats at the local and global level are just a few of the analysis that are presented on the CBS Genome Atlas Web page. Complex analysis, changing methods and frequent addition of new models are factors that require a dynamic database layout. Using basic tools like the GNU Make system, csh, Perl and MySQL, we have created a flexible database environment for storing and maintaining such results for a collection of complete microbial genomes. Currently, these results counts to more than 220 pieces of information. The backbone of this solution consists of a program package written in Perl, which enables administrators to synchronize and update the database content. The MySQL database has been connected to the CBS web-server via PHP4, to present a dynamic web content for users outside the center. This solution is tightly fitted to existing server infrastructure and the solutions proposed here can perhaps serve as a template for other research groups to solve database issues. A web based user interface which is dynamically linked to the Genome Atlas Database can be accessed via www.cbs.dtu.dk/services/GenomeAtlas/. This paper has a supplemental information page which links to the examples presented: www.cbs.dtu.dk/services/GenomeAtlas/suppl/bioinfdatabase.

  20. Development and Implementation of Dynamic Scripts to Support Local Model Verification at National Weather Service Weather Forecast Offices

    NASA Technical Reports Server (NTRS)

    Zavordsky, Bradley; Case, Jonathan L.; Gotway, John H.; White, Kristopher; Medlin, Jeffrey; Wood, Lance; Radell, Dave

    2014-01-01

    Local modeling with a customized configuration is conducted at National Weather Service (NWS) Weather Forecast Offices (WFOs) to produce high-resolution numerical forecasts that can better simulate local weather phenomena and complement larger scale global and regional models. The advent of the Environmental Modeling System (EMS), which provides a pre-compiled version of the Weather Research and Forecasting (WRF) model and wrapper Perl scripts, has enabled forecasters to easily configure and execute the WRF model on local workstations. NWS WFOs often use EMS output to help in forecasting highly localized, mesoscale features such as convective initiation, the timing and inland extent of lake effect snow bands, lake and sea breezes, and topographically-modified winds. However, quantitatively evaluating model performance to determine errors and biases still proves to be one of the challenges in running a local model. Developed at the National Center for Atmospheric Research (NCAR), the Model Evaluation Tools (MET) verification software makes performing these types of quantitative analyses easier, but operational forecasters do not generally have time to familiarize themselves with navigating the sometimes complex configurations associated with the MET tools. To assist forecasters in running a subset of MET programs and capabilities, the Short-term Prediction Research and Transition (SPoRT) Center has developed and transitioned a set of dynamic, easily configurable Perl scripts to collaborating NWS WFOs. The objective of these scripts is to provide SPoRT collaborating partners in the NWS with the ability to evaluate the skill of their local EMS model runs in near real time with little prior knowledge of the MET package. The ultimate goal is to make these verification scripts available to the broader NWS community in a future version of the EMS software. This paper provides an overview of the SPoRT MET scripts, instructions for how the scripts are run, and example use cases.

  1. Exploring the Synergy between Science Literacy and Language Literacy with English Language Learners: Lessons Learned within a Sustained Professional Development Program

    ERIC Educational Resources Information Center

    Carrejo, David J.; Reinhartz, Judy

    2012-01-01

    Thirty-five elementary teachers participated in a yearlong professional development (PD) program whose goal was to foster science content learning while promoting language literacy for English Language Learners (ELL). The researchers utilized an explanatory design methodology to determine the degree to which science and language literacy…

  2. Exploring the US Language Flagship Program: Professional Competence in a Second Language by Graduation

    ERIC Educational Resources Information Center

    Murphy, Dianna, Ed.; Evans-Romaine, Karen, Ed.

    2016-01-01

    A number of reports in the US have highlighted the country's need for improved second language skills for both national security and economic competitiveness. The Language Flagship program, launched in 2002, aims to raise expectations regarding language proficiency levels at the post-secondary level and to address structural gaps in the curricula…

  3. Language Arts for Today's Children. NCTE Curriculum Series, Volume Two.

    ERIC Educational Resources Information Center

    National Council of Teachers of English, Champaign, IL. Commission on the English Curriculum.

    This volume on elementary language programs is divided into four related parts. Part 1 discusses the sources of any effective language program: an understanding of the child's need for language, a knowledge of child development, and an awareness of the continuity essential to growth in language. Part 2 treats the main areas of the language…

  4. English-as-a-Second-Language Programs in Basic Skills Education Program 1

    DTIC Science & Technology

    1984-01-01

    languages and English as a second language . These theories and findings have led, in turn, to the development of new methods for teaching languages ...INTRODUCTION TO TEACHING TECHNIQUES FOR ENGLISH AS A SECOND LANGUAGE . . . . . . . . . . . . 9 Introduction ............................. 9 Traditional Methods ...instruments. q8 . _. ,’,..8 4% .’ II. A BRIEF INTRODUCTION TO TEACHING TECHNIQUES FOR ENGLISH

  5. Staff Report to the Senior Department Official on Recognition Compliance Issues. Recommendation Page: American Speech-Language-Hearing Association

    ERIC Educational Resources Information Center

    US Department of Education, 2010

    2010-01-01

    The American Speech-Language-Hearing Association, Council on Academic Accreditation in Audiology and Speech-Language Pathology (CAA) is a national accrediting agency of graduate education programs in audiology or speech-language pathology. The CAA currently accredits or or preaccredits 319 programs (247 in speech-language pathology and 72 in…

  6. A North and Far North Queensland Initiative: Rethinking the "Why" When Promoting Languages Education

    ERIC Educational Resources Information Center

    Boulard, Florence

    2015-01-01

    Despite the recent Australian Government commitment to supporting schools in growing students into global citizens, language educators cannot rely on this alone to attract new language students. The Young Language Ambassador Program is a new initiative that started in August 2014. The Young Language Ambassador Program is a partnership between…

  7. A Computer Language at the Crossroads: Logo.

    ERIC Educational Resources Information Center

    Thornburg, David D.

    1986-01-01

    Reviews Logo programming language's developmental history, including Papert's vision, creation of LISP, and evolution of Logo from LISP; discusses reasons for Logo not becoming a commonplace programming language; describes Logo program design and its utility for serious programmers; and lists sources of further information on Logo. (MBR)

  8. A Compiler and Run-time System for Network Programming Languages

    DTIC Science & Technology

    2012-01-01

    A Compiler and Run-time System for Network Programming Languages Christopher Monsanto Princeton University Nate Foster Cornell University Rob...Foster, R. Harrison, M. Freedman, C. Monsanto , J. Rexford, A. Story, and D. Walker. Frenetic: A network programming language. In ICFP, Sep 2011. [10] A

  9. Ada--Programming Language of the Future.

    ERIC Educational Resources Information Center

    Rudd, David

    1983-01-01

    Ada is a programing language developed for the Department of Defense, with a registered trademark. It was named for Ada Augusta, coworker of Charles Babbage and the world's first programer. The Department of Defense hopes to prevent variations and to establish Ada as a consistent, standardized language. (MNS)

  10. Introduction to Foreign Languages and Cultures: A New Course to Stimulate Second Language Learning in the Public Schools.

    ERIC Educational Resources Information Center

    Watkins, Stephen A.

    1978-01-01

    Olympic View Middle School has established a program designed to stimulate interest in foreign languages and cultures. The course is intended as an introduction to foreign language and culture study, and is required for all 7th and 8th grade students. Program 1 of the course is taught during one semester of 7th grade, Program 2 during one semester…

  11. Annotated Bibliography of Materials for Elementary Foreign Language Programs.

    ERIC Educational Resources Information Center

    Dobb, Fred

    An annotated bibliography contains about 70 citations of instructional materials and materials concerning curriculum development for elementary school foreign language programs. Citations are included for Arabic, classical languages, French, German, Hebrew, Italian, Japanese, and Spanish. Items on exploratory language courses and general works on…

  12. Peterson's Summer Study Abroad: A Guide to Summer Academic and Language Programs. First Edition.

    ERIC Educational Resources Information Center

    Peterson's Guides, Inc., Princeton, NJ.

    This guide provides descriptions of over 900 summer academic and language study-abroad programs in 80 countries that range from 1-week language study courses to full-summer university programs. An introductory section provides general information on study abroad programs and the use of the guide. The bulk of the guide consists of individual…

  13. Scheduling language and algorithm development study. Volume 1: Study summary and overview

    NASA Technical Reports Server (NTRS)

    1974-01-01

    A high level computer programming language and a program library were developed to be used in writing programs for scheduling complex systems such as the space transportation system. The objectives and requirements of the study are summarized and unique features of the specified language and program library are described and related to the why of the objectives and requirements.

  14. Web-based pathology practice examination usage.

    PubMed

    Klatt, Edward C

    2014-01-01

    General and subject specific practice examinations for students in health sciences studying pathology were placed onto a free public internet web site entitled web path and were accessed four clicks from the home web site menu. Multiple choice questions were coded into. html files with JavaScript functions for web browser viewing in a timed format. A Perl programming language script with common gateway interface for web page forms scored examinations and placed results into a log file on an internet computer server. The four general review examinations of 30 questions each could be completed in up to 30 min. The 17 subject specific examinations of 10 questions each with accompanying images could be completed in up to 15 min each. The results of scores and user educational field of study from log files were compiled from June 2006 to January 2014. The four general review examinations had 31,639 accesses with completion of all questions, for a completion rate of 54% and average score of 75%. A score of 100% was achieved by 7% of users, ≥90% by 21%, and ≥50% score by 95% of users. In top to bottom web page menu order, review examination usage was 44%, 24%, 17%, and 15% of all accessions. The 17 subject specific examinations had 103,028 completions, with completion rate 73% and average score 74%. Scoring at 100% was 20% overall, ≥90% by 37%, and ≥50% score by 90% of users. The first three menu items on the web page accounted for 12.6%, 10.0%, and 8.2% of all completions, and the bottom three accounted for no more than 2.2% each. Completion rates were higher for shorter 10 questions subject examinations. Users identifying themselves as MD/DO scored higher than other users, averaging 75%. Usage was higher for examinations at the top of the web page menu. Scores achieved suggest that a cohort of serious users fully completing the examinations had sufficient preparation to use them to support their pathology education.

  15. A Primer on High-Throughput Computing for Genomic Selection

    PubMed Central

    Wu, Xiao-Lin; Beissinger, Timothy M.; Bauck, Stewart; Woodward, Brent; Rosa, Guilherme J. M.; Weigel, Kent A.; Gatti, Natalia de Leon; Gianola, Daniel

    2011-01-01

    High-throughput computing (HTC) uses computer clusters to solve advanced computational problems, with the goal of accomplishing high-throughput over relatively long periods of time. In genomic selection, for example, a set of markers covering the entire genome is used to train a model based on known data, and the resulting model is used to predict the genetic merit of selection candidates. Sophisticated models are very computationally demanding and, with several traits to be evaluated sequentially, computing time is long, and output is low. In this paper, we present scenarios and basic principles of how HTC can be used in genomic selection, implemented using various techniques from simple batch processing to pipelining in distributed computer clusters. Various scripting languages, such as shell scripting, Perl, and R, are also very useful to devise pipelines. By pipelining, we can reduce total computing time and consequently increase throughput. In comparison to the traditional data processing pipeline residing on the central processors, performing general-purpose computation on a graphics processing unit provide a new-generation approach to massive parallel computing in genomic selection. While the concept of HTC may still be new to many researchers in animal breeding, plant breeding, and genetics, HTC infrastructures have already been built in many institutions, such as the University of Wisconsin–Madison, which can be leveraged for genomic selection, in terms of central processing unit capacity, network connectivity, storage availability, and middleware connectivity. Exploring existing HTC infrastructures as well as general-purpose computing environments will further expand our capability to meet increasing computing demands posed by unprecedented genomic data that we have today. We anticipate that HTC will impact genomic selection via better statistical models, faster solutions, and more competitive products (e.g., from design of marker panels to realized genetic gain). Eventually, HTC may change our view of data analysis as well as decision-making in the post-genomic era of selection programs in animals and plants, or in the study of complex diseases in humans. PMID:22303303

  16. Presurgical language fMRI: Clinical practices and patient outcomes in epilepsy surgical planning.

    PubMed

    Benjamin, Christopher F A; Li, Alexa X; Blumenfeld, Hal; Constable, R Todd; Alkawadri, Rafeed; Bickel, Stephan; Helmstaedter, Christoph; Meletti, Stefano; Bronen, Richard; Warfield, Simon K; Peters, Jurriaan M; Reutens, David; Połczyńska, Monika; Spencer, Dennis D; Hirsch, Lawrence J

    2018-03-12

    The goal of this study was to document current clinical practice and report patient outcomes in presurgical language functional MRI (fMRI) for epilepsy surgery. Epilepsy surgical programs worldwide were surveyed as to the utility, implementation, and efficacy of language fMRI in the clinic; 82 programs responded. Respondents were predominantly US (61%) academic programs (85%), and evaluated adults (44%), adults and children (40%), or children only (16%). Nearly all (96%) reported using language fMRI. Surprisingly, fMRI is used to guide surgical margins (44% of programs) as well as lateralize language (100%). Sites using fMRI for localization most often use a distance margin around activation of 10mm. While considered useful, 56% of programs reported at least one instance of disagreement with other measures. Direct brain stimulation typically confirmed fMRI findings (74%) when guiding margins, but instances of unpredicted decline were reported by 17% of programs and 54% reported unexpected preservation of function. Programs reporting unexpected decline did not clearly differ from those which did not. Clinicians using fMRI to guide surgical margins do not typically map known language-critical areas beyond Broca's and Wernicke's. This initial data shows many clinical teams are confident using fMRI not only for language lateralization but also to guide surgical margins. Reported cases of unexpected language preservation when fMRI activation is resected, and cases of language decline when it is not, emphasize a critical need for further validation. Comprehensive studies comparing commonly-used fMRI paradigms to predict stimulation mapping and post-surgical language decline remain of high importance. © 2018 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc.

  17. PILOT: A Programming Language for Beginners.

    ERIC Educational Resources Information Center

    Schnorr, Janice M.

    The presentation describes PILOT (Programmed Inquiry, Learning or Teaching), a special programing language easy for beginners to learn and available for several brands of microcomputers. PILOT is explained to contain substantially fewer commands than most other languages and to be written in an easy to understand manner. Edit commands and their…

  18. An Analysis of Published Preschool Language Programs.

    ERIC Educational Resources Information Center

    Bartlett, Elsa Jaffe

    For purposes of analysis, preschool language programs can be sorted into four general categories according to the dominant type of learning activity (1) Pattern practice, (2) Cognitive verbalization, (3) Discussion, (4) Role play. Along with definitions of language, the program types differ in the kinds of interactions which occur between teacher…

  19. The Language & International Trade Program at Clemson University.

    ERIC Educational Resources Information Center

    Suarez, Jose I.

    Clemson University (South Carolina) has developed an undergraduate Language and International Trade program designed to train students to meet the needs of American firms doing business overseas. Program aims are that graduates know one foreign language, be attuned to cultural differences, have a business training foundation, and have experience…

  20. 77 FR 72832 - Applications for New Awards; Native American and Alaska Native Children in School Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-06

    ... School Program AGENCY: Office of English Language Acquisition, Department of Education. Overview... participation in language instruction educational programs. Projects funded under the Native American and Alaska... Act of 1965, as amended (ESEA), may support the teaching and studying of Native American languages...

  1. Incidental Foreign-Language Acquisition by Children Watching Subtitled Television Programs

    ERIC Educational Resources Information Center

    Ina, Lekkai

    2014-01-01

    Series of international studies have shown that subtitled television programs provide a rich context for foreign language acquisition. This study investigated whether incidental language acquisition occurs from watching a television program with/without subtitles. Children in the experimental conditions watch: (a) a 15 minute snapshot of a well…

  2. Using Problem Solving to Teach a Programming Language.

    ERIC Educational Resources Information Center

    Milbrandt, George

    1995-01-01

    Computer studies courses should incorporate as many computer concepts and programming language experiences as possible. A gradual increase in problem difficulty will help the student to understand various computer concepts, and the programming language's syntax and structure. A sidebar provides two examples of how to establish a learning…

  3. A Program for Reading and Language Development. An Adopter's Guide.

    ERIC Educational Resources Information Center

    Carter, Nancy Hay

    "Project SAILS" (Symbolic and Innovative Language Systems) is a special program developed by the Portland, Oregon, public schools for training teachers to work with children who have learning and reading difficulties. Teachers are instructed in the use of the Monterey Reading and Language Programs, highly structured and highly…

  4. Professional Development Programs and English Language Instructors: A Critical-Postmodern Study

    ERIC Educational Resources Information Center

    Arikan, Arda

    2004-01-01

    In this completed qualitative dissertation research, the nature of the relationship between professional development programs (in-service training programs) and English language instructors was studied with a critical postmodern lense focusing on the narratives of nine English language instructors on their experiences in their professional…

  5. Professional Development Programs and English Language Instructors: A Critical-Postmodern Study

    ERIC Educational Resources Information Center

    Arikan, Arda

    2004-01-01

    In this completed qualitative dissertation research, the nature of the relationship between professional development programs (in-service training programs) and English language instructors was studied with a critical postmodern lens focusing on the narratives of nine English language instructors on their experiences in their professional…

  6. Closing the Gap Between Specification and Programming: VDM++ and SCALA

    NASA Technical Reports Server (NTRS)

    Havelund, Klaus

    2011-01-01

    We argue that a modern programming language such as Scala offers a level of succinctness, which makes it suitable for program and systems specification as well as for high-level programming. We illustrate this by comparing the language with the Vdm++ specification language. The comparison also identifies areas where Scala perhaps could be improved, inspired by Vdm++. We furthermore illustrate Scala's potential as a specification language by augmenting it with a combination of parameterized state machines and temporal logic, defined as a library, thereby forming an expressive but simple runtime verification framework.

  7. An Analysis of Application Generators.

    DTIC Science & Technology

    1983-03-01

    query language OUEL in the programming language C, THESEUS [20], which embeds relational operators in the language Euclid. Schmidt [21] reports some...34The Design and Implementation of INGRES," ACM-TODS, Vol. 1. No. 3, 1976,. 33 £ 20. Shopiro,J.E., " THESEUS -A Programming Language for Relational

  8. Colorado Model Content Standards: Foreign Language.

    ERIC Educational Resources Information Center

    Colorado State Dept. of Education, Denver.

    The model course content standards for foreign language instruction in Colorado's public schools, K-12, provide guidelines, not curriculum, for school districts to design language programs. An introductory section presents some basic considerations in program design. The two general standards for foreign language performance are that: (1) students…

  9. Bilingualism and Special Education: Program and Pedagogical Issues.

    ERIC Educational Resources Information Center

    Cummins, Jim

    1983-01-01

    Application of the research-based principle that first and second language cognitive and academic development are interdependent and that language acquisition is largely dependent on students receiving sufficient comprehensible input in the target language is discussed in reference to program planning for academically at risk language minority…

  10. Towards programming languages for genetic engineering of living cells

    PubMed Central

    Pedersen, Michael; Phillips, Andrew

    2009-01-01

    Synthetic biology aims at producing novel biological systems to carry out some desired and well-defined functions. An ultimate dream is to design these systems at a high level of abstraction using engineering-based tools and programming languages, press a button, and have the design translated to DNA sequences that can be synthesized and put to work in living cells. We introduce such a programming language, which allows logical interactions between potentially undetermined proteins and genes to be expressed in a modular manner. Programs can be translated by a compiler into sequences of standard biological parts, a process that relies on logic programming and prototype databases that contain known biological parts and protein interactions. Programs can also be translated to reactions, allowing simulations to be carried out. While current limitations on available data prevent full use of the language in practical applications, the language can be used to develop formal models of synthetic systems, which are otherwise often presented by informal notations. The language can also serve as a concrete proposal on which future language designs can be discussed, and can help to guide the emerging standard of biological parts which so far has focused on biological, rather than logical, properties of parts. PMID:19369220

  11. Towards programming languages for genetic engineering of living cells.

    PubMed

    Pedersen, Michael; Phillips, Andrew

    2009-08-06

    Synthetic biology aims at producing novel biological systems to carry out some desired and well-defined functions. An ultimate dream is to design these systems at a high level of abstraction using engineering-based tools and programming languages, press a button, and have the design translated to DNA sequences that can be synthesized and put to work in living cells. We introduce such a programming language, which allows logical interactions between potentially undetermined proteins and genes to be expressed in a modular manner. Programs can be translated by a compiler into sequences of standard biological parts, a process that relies on logic programming and prototype databases that contain known biological parts and protein interactions. Programs can also be translated to reactions, allowing simulations to be carried out. While current limitations on available data prevent full use of the language in practical applications, the language can be used to develop formal models of synthetic systems, which are otherwise often presented by informal notations. The language can also serve as a concrete proposal on which future language designs can be discussed, and can help to guide the emerging standard of biological parts which so far has focused on biological, rather than logical, properties of parts.

  12. How the strengths of Lisp-family languages facilitate building complex and flexible bioinformatics applications

    PubMed Central

    Khomtchouk, Bohdan B; Weitz, Edmund; Karp, Peter D; Wahlestedt, Claes

    2018-01-01

    Abstract We present a rationale for expanding the presence of the Lisp family of programming languages in bioinformatics and computational biology research. Put simply, Lisp-family languages enable programmers to more quickly write programs that run faster than in other languages. Languages such as Common Lisp, Scheme and Clojure facilitate the creation of powerful and flexible software that is required for complex and rapidly evolving domains like biology. We will point out several important key features that distinguish languages of the Lisp family from other programming languages, and we will explain how these features can aid researchers in becoming more productive and creating better code. We will also show how these features make these languages ideal tools for artificial intelligence and machine learning applications. We will specifically stress the advantages of domain-specific languages (DSLs): languages that are specialized to a particular area, and thus not only facilitate easier research problem formulation, but also aid in the establishment of standards and best programming practices as applied to the specific research field at hand. DSLs are particularly easy to build in Common Lisp, the most comprehensive Lisp dialect, which is commonly referred to as the ‘programmable programming language’. We are convinced that Lisp grants programmers unprecedented power to build increasingly sophisticated artificial intelligence systems that may ultimately transform machine learning and artificial intelligence research in bioinformatics and computational biology. PMID:28040748

  13. The impact of threshold language assistance programming on the accessibility of mental health services for persons with limited English proficiency in the Medi-Cal setting.

    PubMed

    McClellan, Sean R; Wu, Frances M; Snowden, Lonnie R

    2012-06-01

    Title VI of the 1964 Civil Rights Act prohibits federal funds recipients from providing care to limited English proficiency (LEP) persons more limited in scope or lower in quality than care provided to others. In 1999, the California Department of Mental Health implemented a "threshold language access policy" to meet its Title VI obligations. Under this policy, Medi-Cal agencies must provide language assistance programming in a non-English language where a county's Medical population contains either 3000 residents or 5% speakers of that language. We examine the impact of threshold language policy-required language assistance programming on LEP persons' access to mental health services by analyzing the county-level penetration rate of services for Russian, Spanish, and Vietnamese speakers across 34 California counties, over 10 years of quarterly data. Exploiting a time series with nonequivalent control group study design, we studied this phenomena using linear regression with random county effects to account for trends over time. Threshold language policy-required assistance programming led to an immediate and significant increase in the penetration rate of mental health services for Russian (8.2, P < 0.01) and Vietnamese (3.3, P < 0.01) language speaking persons. Threshold language assistance programming was effective in increasing mental health access for Russian and Vietnamese, but not for Spanish-speaking LEP persons.

  14. The Rhythm of Language: Fostering Oral and Listening Skills in Singapore Pre-School Children through an Integrated Music and Language Arts Program.

    ERIC Educational Resources Information Center

    Gan, Linda; Chong, Sylvia

    1998-01-01

    Examined the effectiveness of a year-long integrated language and music program (the Expressive Language and Music Project) to enhance Singaporean kindergartners' English oral-language competency. Found that the natural communicative setting and creative use of resources and activities based on the Orff and Kodaly approaches facilitated language…

  15. Cost/Benefit Evaluation of Three English Language Training Programs for Potential Navy Use.

    ERIC Educational Resources Information Center

    Swope, William M.; And Others

    As part of its plans to recruit Hispanic personnel who speak English as a second language, the U.S. Navy will have to provide English language training as well as technical training to prepare these personnel for fleet duty. A cost/benefit analysis was conducted of three English language training programs: the English Technical Language School…

  16. Isozyme variation in lychee (Litchi chinensis Sonn.)

    USDA-ARS?s Scientific Manuscript database

    A genetic diversity analysis involving 49 lychee (Litchi chinensis SOM.) accessions using eight enzyme systems encoding 12 loci (Zdh-I, Zdh-2, Mdh-2, Per-l, Pgi-2, Pgm-1, Pgm-2, Sk& Tpi-1, Tpi-2, Ugpp-1, and Ugpp-2) revealed moderate to high levels of genetic variability. Cluster analysis of the iso...

  17. Advantages of Application of Electronic Commerce in Procurement for the Armed Forces of Brazil and South Korea

    DTIC Science & Technology

    2001-12-01

    Northern Europe.”, Ecommerce Times, [http://www.ecommercetimes.com/perl/story/3546.html], June 2001. Mc Gregor, Don, “Encryption”, [http...sans.org/infosecFAQ/ ecommerce /fraud.htm], September 2001. Schneider, Gary P. and James T. Perry, “Electronic Commerce”, Course Technology, 2001

  18. Relentless Verity: Education for Being-Becoming-Belonging.

    ERIC Educational Resources Information Center

    Kidd, James Robbins

    The dynamic relationship of the concepts of being, becoming, and belonging is and must be the heart and central goal of adult education. The concept can be understood most readily by examination of the writings of humanist psychologists such as Carl Rogers, Fritz Perls, Gordon Allport, and Abraham Maslow. Some characteristics or dimensions of an…

  19. Comparison of effects of glass fibre and glass powder on guinea-pig lungs

    PubMed Central

    Botham, Susan K.; Holt, P. F.

    1973-01-01

    Botham, Susan K., and Holt, P. F. (1973).British Journal of Industrial Medicine,30, 232-236. Comparison of effects of glass fibre and glass powder on guinea-pig lungs. Following 24 hours inhalation by guinea-pigs of powdered glass dust, the pulmonary effects over the succeeding month differed from those previously observed to follow inhalation of glass fibre in that (1) fewer erythrocytes escaped from the capillaries, (2) very few giant cells were produced, (3) erythrocytes and intracellular glass particles were cleared more readily because junctions between respiratory and terminal bronchioles were not blocked by giant cells, (4) intracellular granules containing Perls-positive material did not appreciably increase in number or intensity of staining during the month, and (5) particles were not coated with Perls-positive material during the time that pseudo-asbestos bodies would be formed from glass fibres. The difference between the effects of chemically similar glass powder and fibre during a month in a guinea-pig lung is considered to be due to the morphology of the inhaled particle. Images PMID:4124978

  20. TREE2FASTA: a flexible Perl script for batch extraction of FASTA sequences from exploratory phylogenetic trees.

    PubMed

    Sauvage, Thomas; Plouviez, Sophie; Schmidt, William E; Fredericq, Suzanne

    2018-03-05

    The body of DNA sequence data lacking taxonomically informative sequence headers is rapidly growing in user and public databases (e.g. sequences lacking identification and contaminants). In the context of systematics studies, sorting such sequence data for taxonomic curation and/or molecular diversity characterization (e.g. crypticism) often requires the building of exploratory phylogenetic trees with reference taxa. The subsequent step of segregating DNA sequences of interest based on observed topological relationships can represent a challenging task, especially for large datasets. We have written TREE2FASTA, a Perl script that enables and expedites the sorting of FASTA-formatted sequence data from exploratory phylogenetic trees. TREE2FASTA takes advantage of the interactive, rapid point-and-click color selection and/or annotations of tree leaves in the popular Java tree-viewer FigTree to segregate groups of FASTA sequences of interest to separate files. TREE2FASTA allows for both simple and nested segregation designs to facilitate the simultaneous preparation of multiple data sets that may overlap in sequence content.

  1. Perl Tools for Automating Satellite Ground Systems

    NASA Technical Reports Server (NTRS)

    McLean, David; Haar, Therese; McDonald, James

    2000-01-01

    The freeware scripting language Pert offers many opportunities for automating satellite ground systems for new satellites as well as older, in situ systems. This paper describes a toolkit that has evolved from of the experiences gained by using Pert to automate the ground system for the Compton Gamma Ray Observatory (CGRO) and for automating some of the elements in the Earth Observing System Data and Operations System (EDOS) ground system at Goddard Space Flight Center (GSFC). CGRO is an older ground system that was forced to automate because of fund cuts. Three 8 hour shifts were cut back to one 8 hour shift, 7 days per week. EDOS supports a new mission called Terra, launched December 1999 that requires distribution and tracking of mission-critical reports throughout the world. Both of these ground systems use Pert scripts to process data and display it on the Internet as well as scripts to coordinate many of the other systems that make these ground systems work as a coherent whole. Another task called Automated Multimodal Trend Analysis System (AMTAS) is looking at technology for isolation and recovery of spacecraft problems. This effort has led to prototypes that seek to evaluate various tools and technology that meet at least some of the AMTAS goals. The tools, experiences, and lessons learned by implementing these systems are described here.

  2. Tool for Merging Proposals Into DSN Schedules

    NASA Technical Reports Server (NTRS)

    Khanampornpan, Teerapat; Kwok, John; Call, Jared

    2008-01-01

    A Practical Extraction and Reporting Language (Perl) script called merge7da has been developed to facilitate determination, by a project scheduler in NASA's Deep Space Network, of whether a proposal for use of the DSN could create a conflict with the current DSN schedule. Prior to the development of merge7da, there was no way to quickly identify potential schedule conflicts: it was necessary to submit a proposal and wait a day or two for a response from a DSN scheduling facility. By using merge7da to detect and eliminate potential schedule conflicts before submitting a proposal, a project scheduler saves time and gains assurance that the proposal will probably be accepted. merge7da accepts two input files, one of which contains the current DSN schedule and is in a DSN-standard format called '7da'. The other input file contains the proposal and is in another DSN-standard format called 'C1/C2'. merge7da processes the two input files to produce a merged 7da-format output file that represents the DSN schedule as it would be if the proposal were to be adopted. This 7da output file can be loaded into various DSN scheduling software tools now in use.

  3. An Elementary Language Culture Program.

    ERIC Educational Resources Information Center

    Stones, Valerie

    A five-year course sequence focusing on the relationship of language and culture in world history is described. The program, beginning in grade 3, prepares students for later study of foreign and classical languages, develops English language skills, and cultivates general cultural interest. At the first level, students are introduced to some…

  4. Leadership Practice in Elementary School Dual Language Programs: A Collective Case Study

    ERIC Educational Resources Information Center

    Monroy, Joanie K.

    2012-01-01

    Research in effective programming for English language learners has demonstrated the efficacy of dual language education as a model for closing persistent achievement gaps for this growing population of students. With goals of high academic achievement, linguistic proficiency in two languages, and cross-cultural proficiency, dual language…

  5. Foreign Language Writing Fellows Programs: A Model for Improving Advanced Writing Skills

    ERIC Educational Resources Information Center

    Snyder, Delys Waite; Nielson, Rex P.; Kurzer, Kendon

    2016-01-01

    Within the growing field of scholarly literature on foreign language (FL) writing pedagogy, few studies have addressed pedagogical questions regarding the teaching of writing to advanced language learners. Writing fellows peer tutoring programs, although typically associated with first language writing instruction, likely can benefit and support…

  6. Setting Evidence-Based Language Goals

    ERIC Educational Resources Information Center

    Goertler, Senta; Kraemer, Angelika; Schenker, Theresa

    2016-01-01

    The purpose of this project was to identify target language benchmarks for the German program at Michigan State University (MSU) based on national and international guidelines and previous research, to assess language skills across course levels and class sections in the entire German program, and to adjust the language benchmarks as needed based…

  7. Language Arts Program Guide, K-12.

    ERIC Educational Resources Information Center

    Hawaii State Dept. of Education, Honolulu. Office of Instructional Services.

    Intended for use by administrators, teachers, and district and state personnel, this guide provides a framework for Hawaii's kindergarten through grade 12 language arts program. Various sections of the guide contain (1) a statement of beliefs concerning the nature of language, language and learning, the student, and the school climate; (2) program…

  8. Programming Languages, Natural Languages, and Mathematics

    ERIC Educational Resources Information Center

    Naur, Peter

    1975-01-01

    Analogies are drawn between the social aspects of programming and similar aspects of mathematics and natural languages. By analogy with the history of auxiliary languages it is suggested that Fortran and Cobol will remain dominant. (Available from the Association of Computing Machinery, 1133 Avenue of the Americas, New York, NY 10036.) (Author/TL)

  9. Computer-Assisted Language Learning: Current Programs and Projects. ERIC Digest.

    ERIC Educational Resources Information Center

    Higgins, Chris

    For many years, foreign language teachers have used the computer to provide supplemental exercises in the instruction of foreign languages. In recent years, advances in computer technology have motivated teachers to reassess the computer and consider it a valuable part of daily foreign language learning. Innovative software programs, authoring…

  10. The English Language Learner Program Survey for Principals. REL 2014-027

    ERIC Educational Resources Information Center

    Grady, Matthew W.; O'Dwyer, Laura M.

    2014-01-01

    REL Northeast & Islands at Education Development Center, in partnership with the English Language Learners Alliance, has developed a new survey tool--The English Language Learner Program Survey for Principals--to help state education departments collect consistent data on the education of English language learner students. Designed for school…

  11. A Programming Language Environment for the Unassisted Learner.

    ERIC Educational Resources Information Center

    Thomas, P. G.; Ince, D. C.

    1982-01-01

    Describes the computing environment and command language for a new programing language called OUSBASIC which is designed to enable naive users to interact usefully, with little assistance, with a computer system. (Author/CHC)

  12. Association of mandated language access programming and quality of care provided by mental health agencies.

    PubMed

    McClellan, Sean R; Snowden, Lonnie

    2015-01-01

    This study examined the association between language access programming and quality of psychiatric care received by persons with limited English proficiency (LEP). In 1999, the California Department of Mental Health required county Medicaid agencies to implement a "threshold language access policy" to meet the state's Title VI obligations. This policy required Medi-Cal agencies to provide language access programming, including access to interpreters and translated written material, to speakers of languages other than English if the language was spoken by at least 3,000, or 5%, of the county's Medicaid population. Using a longitudinal study design with a nonequivalent control group, this study examined the quality of care provided to Spanish speakers with LEP and a severe mental illness before and after implementation of mandatory language access programming. Quality was measured by receipt of at least two follow-up medication visits within 90 days or three visits within 180 days of an initial medication visit over a period of 38 quarter-years. On average, only 40% of Spanish-speaking clients received at least three medication follow-up visits within 180 days. In multivariate analyses, language access programming was not associated with receipt of at least two medication follow-up visits within 90 days or at least three visits within 180 days. This study found no evidence that language access programming led to increased rates of follow-up medication visits for clients with LEP.

  13. Real-Time MENTAT programming language and architecture

    NASA Technical Reports Server (NTRS)

    Grimshaw, Andrew S.; Silberman, Ami; Liu, Jane W. S.

    1989-01-01

    Real-time MENTAT, a programming environment designed to simplify the task of programming real-time applications in distributed and parallel environments, is described. It is based on the same data-driven computation model and object-oriented programming paradigm as MENTAT. It provides an easy-to-use mechanism to exploit parallelism, language constructs for the expression and enforcement of timing constraints, and run-time support for scheduling and exciting real-time programs. The real-time MENTAT programming language is an extended C++. The extensions are added to facilitate automatic detection of data flow and generation of data flow graphs, to express the timing constraints of individual granules of computation, and to provide scheduling directives for the runtime system. A high-level view of the real-time MENTAT system architecture and programming language constructs is provided.

  14. Ada Linear-Algebra Program

    NASA Technical Reports Server (NTRS)

    Klumpp, A. R.; Lawson, C. L.

    1988-01-01

    Routines provided for common scalar, vector, matrix, and quaternion operations. Computer program extends Ada programming language to include linear-algebra capabilities similar to HAS/S programming language. Designed for such avionics applications as software for Space Station.

  15. Quantification and Formalization of Security

    DTIC Science & Technology

    2010-02-01

    Quantification of Information Flow . . . . . . . . . . . . . . . . . . 30 2.4 Language Semantics . . . . . . . . . . . . . . . . . . . . . . . . . . 46...system behavior observed by users holding low clearances. This policy, or a variant of it, is enforced by many pro- gramming language -based mechanisms...illustrates with a particular programming language (while-programs plus probabilistic choice). The model is extended in §2.5 to programs in which

  16. US Directory of Foreign Language Education Programs.

    ERIC Educational Resources Information Center

    Grosse, Christine Uber

    The preparation of a directory of foreign language education programs was a response to the lack of an information source for location or curricular content of programs in foreign language pedagogy, and followed the lead of other associations in the United States and abroad in compiling such information. Despite having developed guidelines for…

  17. Language and Culture Immersion: A Winning Enterprise.

    ERIC Educational Resources Information Center

    Cormier, Raymond

    A second language program developed at Wilson College (Chambersburg, Pennsylvania) with a federal grant uses the Rassias Method of theatrical, dramatic language saturation. In the first application of the program at the college, peer tutors (who would be assistant teachers in the subsequent immersion program) were trained in a three-day workshop.…

  18. Nociones de la programacion de lenguas extranjeras; Ensayo metodologico (II) (Notions on Programed Instruction in Foreign Languages; Methodological Essay II)

    ERIC Educational Resources Information Center

    Feldman, David

    1975-01-01

    This paper discusses the prerequisites to programed language instruction, the role of the native language and the level of skill, and then explains materials and machines needed for such a program. Particular attention is given to phonetics. (Text is in Spanish.) (CK)

  19. The Relationships among Group Size, Participation, and Performance of Programming Language Learning Supported with Online Forums

    ERIC Educational Resources Information Center

    Shaw, Ruey-Shiang

    2013-01-01

    This study examined the relationships among group size, participation, and learning performance factors when learning a programming language in a computer-supported collaborative learning (CSCL) context. An online forum was used as the CSCL environment for learning the Microsoft ASP.NET programming language. The collaborative-learning experiment…

  20. Supporting Caregivers in Developing Responsive Communication Partnerships with Their Children: Extending a Caregiver-Led Interactive Language Program

    ERIC Educational Resources Information Center

    Cologon, Kathy; Wicks, Lilly; Salvador, Aliza

    2017-01-01

    This study investigates whether extension of a caregiver-led interactive language program may enhance its effectiveness in supporting communication. Caregiver-led language programs, which focus on establishing responsive interaction patterns to support opportunities for communication between caregivers and young children within natural settings,…

  1. Guide to Conducting a Language Immersion/Homestay Program.

    ERIC Educational Resources Information Center

    Drysdale, Susan; Killelea, Frances

    This handbook, designed to assist foreign language teachers in planning and executing a language immersion/homestay program for their students, is based on a successful program in Switzerland undertaken by Northport (New York) High School French teachers in 1980. The material is presented in three parts: (1) preparation of the exchange, including…

  2. Impact of Augmented Reality on Programming Language Learning: Efficiency and Perception

    ERIC Educational Resources Information Center

    Teng, Chin-Hung; Chen, Jr-Yi; Chen, Zhi-Hong

    2018-01-01

    Although the learning of programming language is critical in science and technology education, it might be difficult for some students, especially novices. One possible reason might be the fact that programming language, especially for three-dimensional (3D) applications, is too complex and abstract for these students to understand. Programming…

  3. Master Program in Foreign Language Education at New York University Steinhardt (US)

    ERIC Educational Resources Information Center

    Ikonnikova, Maryna

    2016-01-01

    The article deals with master program in foreign language education at New York University Steinhardt (US). Thus, its peculiarities have been revealed. It has been defined that the study program presupposes mastering of foreign language teaching approaches that meet various needs of learners. It has been indicated that students acquire the…

  4. Evaluative Case Study on the Efficacy of the ELPS Program in Mathematics

    ERIC Educational Resources Information Center

    Perez, Malia Ann

    2013-01-01

    The English Language Proficiency Standards (ELPS) program was developed to address the need to effectively integrate second language acquisition with quality content area instruction. English language learners (ELLs) have struggled on standardized tests and there has been little empirical evidence regarding the impact of the ELPS program on…

  5. 34 CFR 657.1 - What is the Foreign Language and Area Studies Fellowships Program?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... institutions of higher education, to students who are— (a) Enrolled for undergraduate or graduate training in a... foreign language training or training in a program for which performance-based modern foreign language... Fellowships Program? 657.1 Section 657.1 Education Regulations of the Offices of the Department of Education...

  6. 34 CFR 657.1 - What is the Foreign Language and Area Studies Fellowships Program?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... institutions of higher education, to students who are— (a) Enrolled for undergraduate or graduate training in a... foreign language training or training in a program for which performance-based modern foreign language... Fellowships Program? 657.1 Section 657.1 Education Regulations of the Offices of the Department of Education...

  7. 34 CFR 657.1 - What is the Foreign Language and Area Studies Fellowships Program?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... institutions of higher education, to students who are— (a) Enrolled for undergraduate or graduate training in a... foreign language training or training in a program for which performance-based modern foreign language... Fellowships Program? 657.1 Section 657.1 Education Regulations of the Offices of the Department of Education...

  8. 34 CFR 657.1 - What is the Foreign Language and Area Studies Fellowships Program?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... institutions of higher education, to students who are— (a) Enrolled for undergraduate or graduate training in a... foreign language training or training in a program for which performance-based modern foreign language... Fellowships Program? 657.1 Section 657.1 Education Regulations of the Offices of the Department of Education...

  9. 34 CFR 657.1 - What is the Foreign Language and Area Studies Fellowships Program?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... institutions of higher education, to students who are— (a) Enrolled for undergraduate or graduate training in a... foreign language training or training in a program for which performance-based modern foreign language... Fellowships Program? 657.1 Section 657.1 Education Regulations of the Offices of the Department of Education...

  10. Requirements for Programming Languages in Computer-Based Instructional Systems.

    ERIC Educational Resources Information Center

    Zinn, Karl

    The author reviews the instructional programing languages which already exist and describes their methods of presentation, organization, and preparation. He recommends that all research and development projects remain flexible in their choice of programing language for a time yet. He suggests ways to adapt to specific uses and users, to exploit…

  11. Project HAPI (Handicapped Achievement Program Improvement): Assessment plus Intervention equal I.E.P. A Handbook on How To Write an Individualized Education Program for Severe Disorders of Language, Including Aphasia and Other Speech-Language Handicapped (Communication Disorders). Book One.

    ERIC Educational Resources Information Center

    Chapman, Jean

    The first of five handbooks developed by Project HAPI (Handicapped Achievement Program Improvement), a multimedia staff development program to help teachers and specialists write effective individualized education programs (IEPs), is in looseleaf workbook format and focuses on children with severe disorders of language, including aphasia and other…

  12. A Comparison of Inter-Professional Education Programs in Preparing Prospective Teachers and Speech and Language Pathologists for Collaborative Language-Literacy Instruction

    ERIC Educational Resources Information Center

    Wilson, Leanne; McNeill, Brigid; Gillon, Gail T.

    2016-01-01

    Ensuring teacher and speech and language pathology graduates are prepared to work collaboratively together to meet the diverse language literacy learning needs of children is an important goal. This study investigated the efficacy of a 3-h inter-professional education program focused on explicit instruction in the language skills that underpin…

  13. Implementing Task-Based Language Teaching to Integrate Language Skills in an EFL Program at a Colombian University

    ERIC Educational Resources Information Center

    Córdoba Zúñiga, Eulices

    2016-01-01

    This article reports the findings of a qualitative research study conducted with six first semester students of an English as a foreign language program in a public university in Colombia. The aim of the study was to implement task-based language teaching as a way to integrate language skills and help learners to improve their communicative…

  14. New insights into Fe localization in plant tissues

    PubMed Central

    Roschzttardtz, Hannetz; Conéjéro, Geneviève; Divol, Fanchon; Alcon, Carine; Verdeil, Jean-Luc; Curie, Catherine; Mari, Stéphane

    2013-01-01

    Deciphering cellular iron (Fe) homeostasis requires having access to both quantitative and qualitative information on the subcellular pools of Fe in tissues and their dynamics within the cells. We have taken advantage of the Perls/DAB Fe staining procedure to perform a systematic analysis of Fe distribution in roots, leaves and reproductive organs of the model plant Arabidopsis thaliana, using wild-type and mutant genotypes affected in iron transport and storage. Roots of soil-grown plants accumulate iron in the apoplast of the central cylinder, a pattern that is strongly intensified when the citrate effluxer FRD3 is not functional, thus stressing the importance of citrate in the apoplastic movement of Fe. In leaves, Fe level is low and only detected in and around vascular tissues. In contrast, Fe staining in leaves of iron-treated plants extends in the surrounding mesophyll cells where Fe deposits, likely corresponding to Fe-ferritin complexes, accumulate in the chloroplasts. The loss of ferritins in the fer1,3,4 triple mutant provoked a massive accumulation of Fe in the apoplastic space, suggesting that in the absence of iron buffering in the chloroplast, cells activate iron efflux and/or repress iron influx to limit the amount of iron in the cell. In flowers, Perls/DAB staining has revealed a major sink for Fe in the anthers. In particular, developing pollen grains accumulate detectable amounts of Fe in small-size intracellular bodies that aggregate around the vegetative nucleus at the binuclear stage and that were identified as amyloplasts. In conclusion, using the Perls/DAB procedure combined to selected mutant genotypes, this study has established a reliable atlas of Fe distribution in the main Arabidopsis organs, proving and refining long-assumed intracellular locations and uncovering new ones. This “iron map” of Arabidopsis will serve as a basis for future studies of possible actors of iron movement in plant tissues and cell compartments. PMID:24046774

  15. A progress report on a NASA research program for embedded computer systems software

    NASA Technical Reports Server (NTRS)

    Foudriat, E. C.; Senn, E. H.; Will, R. W.; Straeter, T. A.

    1979-01-01

    The paper presents the results of the second stage of the Multipurpose User-oriented Software Technology (MUST) program. Four primary areas of activities are discussed: programming environment, HAL/S higher-order programming language support, the Integrated Verification and Testing System (IVTS), and distributed system language research. The software development environment is provided by the interactive software invocation system. The higher-order programming language (HOL) support chosen for consideration is HAL/S mainly because at the time it was one of the few HOLs with flight computer experience and it is the language used on the Shuttle program. The overall purpose of IVTS is to provide a 'user-friendly' software testing system which is highly modular, user controlled, and cooperative in nature.

  16. L3 Interactive Data Language

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hohn, Michael; Adams, Paul

    2006-09-05

    The L3 system is a computational steering environment for image processing and scientific computing. It consists of an interactive graphical language and interface. Its purpose is to help advanced users in controlling their computational software and assist in the management of data accumulated during numerical experiments. L3 provides a combination of features not found in other environments; these are: - textual and graphical construction of programs - persistence of programs and associated data - direct mapping between the scripts, the parameters, and the produced data - implicit hierarchial data organization - full programmability, including conditionals and functions - incremental executionmore » of programs The software includes the l3 language and the graphical environment. The language is a single-assignment functional language; the implementation consists of lexer, parser, interpreter, storage handler, and editing support, The graphical environment is an event-driven nested list viewer/editor providing graphical elements corresponding to the language. These elements are both the represenation of a users program and active interfaces to the values computed by that program.« less

  17. The Role of Linguistics and Linguistic Analysis in Programs under Title VI of the National Defense Education Act of 1958: A Statement by the Committee on Language Programs, American Council of Learned Societies.

    ERIC Educational Resources Information Center

    Carroll, John B.; And Others

    Concentrating on five ways in which foreign language teaching can be aided by linguistic science, the Committee on Language Programs, established by the American Council of Learned Societies, expresses its support of the National Defense Education Act of 1958, Title VI; and the Language Development Section of the Department of Health, Education,…

  18. The Impact of Vietnam's Globalization on National Education Policies and Teacher Training Programs for Teachers of English as an International Language: A Case Study of the University of Pedagogy in Ho Chi Minh City

    ERIC Educational Resources Information Center

    Lam, Tri Ly

    2011-01-01

    The Problem: The purpose of this study was to investigate the impact of Vietnam's globalization on national language education policies and teacher training programs for teachers of English to speakers of other languages. Specifically, this research explored the extent to which the new policies for English language training programs adopted by the…

  19. Evaluation of English Language Development Programs in the Santa Ana Unified School District. A Report on Data System Reliability and Statistical Modeling of Program Impacts.

    ERIC Educational Resources Information Center

    Mitchell, Douglas E.; Destino, Tom; Karam, Rita

    In response to concern about the effectiveness of programs for English-as-a-Second-Language students in California's schools, the Santa Ana Unified School District, in which over 80 percent of students are limited-English-proficient (LEP) conducted a study of both the operations and effectiveness of the district's language development program,…

  20. "Doing Good" in Italian through Student Community Engagement: The Benefits of Language Placements

    ERIC Educational Resources Information Center

    Bouvet, Eric; Cosmini, Daniela; Palaktsoglou, Maria; Vanzo, Lynn

    2017-01-01

    This article discusses a community engagement pilot program for language students offered at Flinders University. For a number of years, the "Language in Action" program has provided placement opportunities for language students in a range of community settings such as aged-care agencies and cultural associations. From an educational…

  1. 25 CFR 39.133 - Who decides how Language Development funds can be used?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... INDIAN SCHOOL EQUALIZATION PROGRAM Indian School Equalization Formula Language Development Programs § 39.133 Who decides how Language Development funds can be used? Tribal governing bodies or local school... 25 Indians 1 2010-04-01 2010-04-01 false Who decides how Language Development funds can be used...

  2. Responding to the Diversity of Chinese Language Learners in Australian Schools

    ERIC Educational Resources Information Center

    Scrimgeour, Andrew

    2014-01-01

    Until recently Chinese language learning in Australian primary and junior secondary schools has been characterised by programs primarily designed for second language learners who have had no prior knowledge of or exposure to Chinese language. Participation in such programs by Australian-born children who speak Putonghua (Mandarin) or another…

  3. Commercial Language, Business Economics, and the Liberal Arts Curriculum.

    ERIC Educational Resources Information Center

    Sell, John W.; And Others

    A program at the College of Wooster (Ohio) in commercial language and international business is described. The program was undertaken with private funds and within the context of a traditional liberal arts college. It has three main curricular goals: (1) additional training of language instructors for language courses that would include the…

  4. Nociones de la programacion de lenguas extranjeras: ensayo metodologico (Notions on the Programming of Foreign Languages: Methodological Experiment)

    ERIC Educational Resources Information Center

    Feldman, David

    1975-01-01

    Presents a computerized program for foreign language learning giving drills for all the major language skills. The drills are followed by an extensive bibliography of documents in some way dealing with computer based instruction, particularly foreign language instruction. (Text is in Spanish.) (TL)

  5. Foreign Language Academy

    ERIC Educational Resources Information Center

    Palandra, Maria

    2008-01-01

    As interest in the study of foreign languages grows, more and more school and district leaders will be charged with the responsibility of establishing a language program. Some of the questions that they will need to answer include: What language and what model should be selected? How could another program be inserted in a school day already…

  6. African Language Instruction at the University of Wisconsin: A HEA Title VI-Funded Program.

    ERIC Educational Resources Information Center

    Kuntz, Patricia S.

    This paper describes the evolution of African language instruction at the University of Wisconsin, examining how faculty and staff have utilized state and federal funding to promote the national capacity in African language proficiency. Six sections describe the program's evolution: "Language Instruction at Wisconsin"; "Origins of…

  7. 25 CFR 39.133 - Who decides how Language Development funds can be used?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... SCHOOL EQUALIZATION PROGRAM Indian School Equalization Formula Language Development Programs § 39.133 Who decides how Language Development funds can be used? Tribal governing bodies or local school boards decide... 25 Indians 1 2012-04-01 2011-04-01 true Who decides how Language Development funds can be used? 39...

  8. 25 CFR 39.133 - Who decides how Language Development funds can be used?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... INDIAN SCHOOL EQUALIZATION PROGRAM Indian School Equalization Formula Language Development Programs § 39.133 Who decides how Language Development funds can be used? Tribal governing bodies or local school... 25 Indians 1 2014-04-01 2014-04-01 false Who decides how Language Development funds can be used...

  9. 25 CFR 39.133 - Who decides how Language Development funds can be used?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... INDIAN SCHOOL EQUALIZATION PROGRAM Indian School Equalization Formula Language Development Programs § 39.133 Who decides how Language Development funds can be used? Tribal governing bodies or local school... 25 Indians 1 2013-04-01 2013-04-01 false Who decides how Language Development funds can be used...

  10. 25 CFR 39.133 - Who decides how Language Development funds can be used?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Who decides how Language Development funds can be used... INDIAN SCHOOL EQUALIZATION PROGRAM Indian School Equalization Formula Language Development Programs § 39.133 Who decides how Language Development funds can be used? Tribal governing bodies or local school...

  11. Research in Second Language Studies at Michigan State University

    ERIC Educational Resources Information Center

    White, Benjamin; , Fei, Fei; Russell, Marthe

    2009-01-01

    The Second Language Studies (SLS) Program was established in 2005 with the express purpose of providing "a firm foundation in the field of Second Language Acquisition and its application to current second language research and teaching" (http://sls.msu.edu). Under the leadership of Professor Susan Gass, the program has grown to include…

  12. Language and Ethnicity: Multiple Literacies in Context, Language Education in Guatemala

    ERIC Educational Resources Information Center

    Helmberger, Janet L.

    2006-01-01

    This study focuses on the research literature available in the United States on the evolution of language policy and planning issues involved in bilingual education programs in Mayan communities in Guatemala. I begin with general comments regarding language policy and planning for bilingual programs for ethnic groups within the borders of…

  13. Handbook for Classroom Testing in Peace Corps Language Programs. Manual T0068.

    ERIC Educational Resources Information Center

    Anderson, Neil J.

    This manual provides instructors in Peace Corps language training programs with information about two kinds of classroom testing: formative, ongoing testing and summative testing that occurs at the end of an instructional period. The first of the manual's four chapters on the purposes of language testing, discusses language testing within a…

  14. Computer Languages: A Practical Guide to the Chief Programming Languages.

    ERIC Educational Resources Information Center

    Sanderson, Peter C.

    All the most commonly-used high-level computer languages are discussed in this book. An introductory discussion provides an overview of the basic components of a digital computer, the general planning of a computer programing problem, and the various types of computer languages. Each chapter is self-contained, emphasizes those features of a…

  15. BASIC, Logo, and Pilot: A Comparison of Three Computer Languages.

    ERIC Educational Resources Information Center

    Maddux, Cleborne D.; Cummings, Rhoda E.

    1985-01-01

    Following a brief history of Logo, BASIC, and Pilot programing languages, common educational programing tasks (input from keyboard, evaluation of keyboard input, and computation) are presented in each language to illustrate how each can be used to perform the same tasks and to demonstrate each language's strengths and weaknesses. (MBR)

  16. The Marketing of the Business Language Program.

    ERIC Educational Resources Information Center

    Morello, Joseph G.

    The University of Rhode Island, through the cooperation of its College of Business Administration and Department of Languages, has undertaken efforts to market its business language program. The target group consists of the incoming freshman class, all of whom must have completed 2 years of high school language study and do some college work in a…

  17. Investigating the Relationship between Iranian EFL Teachers' Autonomy and Their Neuro-Linguistic Programming

    ERIC Educational Resources Information Center

    Hosseinzadeh, Ehsan; Baradaran, Abdollah

    2015-01-01

    The present study was an attempt to investigate the relationship between English Language Teachers' autonomy and their Neuro-linguistic Programming (NLP). To this end, a group of 200 experienced English language teachers at various language schools in Tehran, inter alia, Asre Zaban Language Academy, were given two questionnaires namely Teaching…

  18. When technology became language: the origins of the linguistic conception of computer programming, 1950-1960.

    PubMed

    Nofre, David; Priestley, Mark; Alberts, Gerard

    2014-01-01

    Language is one of the central metaphors around which the discipline of computer science has been built. The language metaphor entered modern computing as part of a cybernetic discourse, but during the second half of the 1950s acquired a more abstract meaning, closely related to the formal languages of logic and linguistics. The article argues that this transformation was related to the appearance of the commercial computer in the mid-1950s. Managers of computing installations and specialists on computer programming in academic computer centers, confronted with an increasing variety of machines, called for the creation of "common" or "universal languages" to enable the migration of computer code from machine to machine. Finally, the article shows how the idea of a universal language was a decisive step in the emergence of programming languages, in the recognition of computer programming as a proper field of knowledge, and eventually in the way we think of the computer.

  19. Do cognitive, language, or physical impairments affect participation in a trial of self-management programs for stroke?

    PubMed

    Cadilhac, Dominique A; Kilkenny, Monique F; Srikanth, Velandai; Lindley, Richard I; Lalor, Erin; Osborne, Richard H; Batterbsy, Malcolm

    2016-01-01

    Research studies may have limited generalizability when survivors of stroke with physical, language, or cognitive impairments are excluded. To assess whether presence of cognitive, language, or global impairments affects participation in self-management programs. Stroke survivors were recruited in South Australia from seven hospitals or via advertisements into a randomized controlled trial (1:1:1 ratio) of a Stroke Self-Management Program, the Stanford chronic condition self-management program, or standard care. Impairment status was measured using: Cognistat (cognition), Frenchay Aphasia assessment (language), modified Rankin Score (mRS; where score 3-5 = global disability). participation (i.e. booked, accessed, and completed a program (defined as attending ≥ 50% of sessions)) and safety (i.e. adverse events). Outcomes were compared by impairment status. Among 315 people screened 143/149 eligible were randomized (median age 71 years; 41% male; with impairments: 62% cognitive, 34% language, 64% global disability). Participation did not differ by cognitive or language impairment status (cognitive 75%, no cognitive 68%, p = 0.54; language 78%, no language 69%, p = 0.42). However, participation did vary by global impairment status (global disability 61%, no disability 96%, p < 0.001). Participants with cognitive impairment experienced more adverse events (severe n = 9 versus no cognitive impairment n = 1). Survivors of stroke with cognitive, language, or global impairments are able to participate in self-management programs and should be included in these types of research studies or programs. Reduced participation by those with global disability and the possibility of more adverse events in people with cognitive impairments needs to be considered. © 2016 World Stroke Organization.

  20. Algorithm Building and Learning Programming Languages Using a New Educational Paradigm

    NASA Astrophysics Data System (ADS)

    Jain, Anshul K.; Singhal, Manik; Gupta, Manu Sheel

    2011-08-01

    This research paper presents a new concept of using a single tool to associate syntax of various programming languages, algorithms and basic coding techniques. A simple framework has been programmed in Python that helps students learn skills to develop algorithms, and implement them in various programming languages. The tool provides an innovative and a unified graphical user interface for development of multimedia objects, educational games and applications. It also aids collaborative learning amongst students and teachers through an integrated mechanism based on Remote Procedure Calls. The paper also elucidates an innovative method for code generation to enable students to learn the basics of programming languages using drag-n-drop methods for image objects.

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