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Sample records for permutation flow shop

  1. Multi-Objective Simulating Annealing for Permutation Flow Shop Problems

    NASA Astrophysics Data System (ADS)

    Mokotoff, E.; Pérez, J.

    2007-09-01

    Real life scheduling problems require more than one criterion. Nevertheless, the complex nature of the Permutation Flow Shop problem has prevented the development of models with multiple criteria. Considering only one regular criterion, this scheduling problem was shown to be NP-complete. The Multi-Objective Simulated Annealing (MOSA) methods are metaheuristics based on Simulated Annealing to solve Multi-Objective Combinatorial Optimization (MOCO) problems, like the problem at hand. Starting from the general MOSA method introduced by Loukil et al. [1], we developed MOSA models to provide the decision maker with efficient solutions for the Permutation Flow Shop problem (common in the production of ceramic tiles). In this paper we present three models: two bicriteria models and one based on satisfaction levels for the main criterion.

  2. Discrete bat algorithm for optimal problem of permutation flow shop scheduling.

    PubMed

    Luo, Qifang; Zhou, Yongquan; Xie, Jian; Ma, Mingzhi; Li, Liangliang

    2014-01-01

    A discrete bat algorithm (DBA) is proposed for optimal permutation flow shop scheduling problem (PFSP). Firstly, the discrete bat algorithm is constructed based on the idea of basic bat algorithm, which divide whole scheduling problem into many subscheduling problems and then NEH heuristic be introduced to solve subscheduling problem. Secondly, some subsequences are operated with certain probability in the pulse emission and loudness phases. An intensive virtual population neighborhood search is integrated into the discrete bat algorithm to further improve the performance. Finally, the experimental results show the suitability and efficiency of the present discrete bat algorithm for optimal permutation flow shop scheduling problem.

  3. Discrete Bat Algorithm for Optimal Problem of Permutation Flow Shop Scheduling

    PubMed Central

    Luo, Qifang; Zhou, Yongquan; Xie, Jian; Ma, Mingzhi; Li, Liangliang

    2014-01-01

    A discrete bat algorithm (DBA) is proposed for optimal permutation flow shop scheduling problem (PFSP). Firstly, the discrete bat algorithm is constructed based on the idea of basic bat algorithm, which divide whole scheduling problem into many subscheduling problems and then NEH heuristic be introduced to solve subscheduling problem. Secondly, some subsequences are operated with certain probability in the pulse emission and loudness phases. An intensive virtual population neighborhood search is integrated into the discrete bat algorithm to further improve the performance. Finally, the experimental results show the suitability and efficiency of the present discrete bat algorithm for optimal permutation flow shop scheduling problem. PMID:25243220

  4. An effective hybrid immune algorithm for solving the distributed permutation flow-shop scheduling problem

    NASA Astrophysics Data System (ADS)

    Xu, Ye; Wang, Ling; Wang, Shengyao; Liu, Min

    2014-09-01

    In this article, an effective hybrid immune algorithm (HIA) is presented to solve the distributed permutation flow-shop scheduling problem (DPFSP). First, a decoding method is proposed to transfer a job permutation sequence to a feasible schedule considering both factory dispatching and job sequencing. Secondly, a local search with four search operators is presented based on the characteristics of the problem. Thirdly, a special crossover operator is designed for the DPFSP, and mutation and vaccination operators are also applied within the framework of the HIA to perform an immune search. The influence of parameter setting on the HIA is investigated based on the Taguchi method of design of experiment. Extensive numerical testing results based on 420 small-sized instances and 720 large-sized instances are provided. The effectiveness of the HIA is demonstrated by comparison with some existing heuristic algorithms and the variable neighbourhood descent methods. New best known solutions are obtained by the HIA for 17 out of 420 small-sized instances and 585 out of 720 large-sized instances.

  5. A multipopulation PSO based memetic algorithm for permutation flow shop scheduling.

    PubMed

    Liu, Ruochen; Ma, Chenlin; Ma, Wenping; Li, Yangyang

    2013-01-01

    The permutation flow shop scheduling problem (PFSSP) is part of production scheduling, which belongs to the hardest combinatorial optimization problem. In this paper, a multipopulation particle swarm optimization (PSO) based memetic algorithm (MPSOMA) is proposed in this paper. In the proposed algorithm, the whole particle swarm population is divided into three subpopulations in which each particle evolves itself by the standard PSO and then updates each subpopulation by using different local search schemes such as variable neighborhood search (VNS) and individual improvement scheme (IIS). Then, the best particle of each subpopulation is selected to construct a probabilistic model by using estimation of distribution algorithm (EDA) and three particles are sampled from the probabilistic model to update the worst individual in each subpopulation. The best particle in the entire particle swarm is used to update the global optimal solution. The proposed MPSOMA is compared with two recently proposed algorithms, namely, PSO based memetic algorithm (PSOMA) and hybrid particle swarm optimization with estimation of distribution algorithm (PSOEDA), on 29 well-known PFFSPs taken from OR-library, and the experimental results show that it is an effective approach for the PFFSP.

  6. A new Nawaz-Enscore-Ham-based heuristic for permutation flow-shop problems with bicriteria of makespan and machine idle time

    NASA Astrophysics Data System (ADS)

    Liu, Weibo; Jin, Yan; Price, Mark

    2016-10-01

    A new heuristic based on the Nawaz-Enscore-Ham algorithm is proposed in this article for solving a permutation flow-shop scheduling problem. A new priority rule is proposed by accounting for the average, mean absolute deviation, skewness and kurtosis, in order to fully describe the distribution style of processing times. A new tie-breaking rule is also introduced for achieving effective job insertion with the objective of minimizing both makespan and machine idle time. Statistical tests illustrate better solution quality of the proposed algorithm compared to existing benchmark heuristics.

  7. Multi-objective Local Search Combined with NSGA-II for Bi-criteria Permutation Flow Shop Scheduling Problem

    NASA Astrophysics Data System (ADS)

    Wei, Xiu; Zhang, Wenqiang; Weng, Wei; Fujimura, Shigeru

    This paper proposed a multi-objective local search procedure (MOLS). It is combined with NSGA-II for solving bi-criteria PFSP with the objectives of minimizing makespan and maximum tardiness. Utilizing the properties of active blocks for flow shop scheduling problem, neighborhood structures MOINS (multi-objective insertion) and MOEXC (multi-objective exchange) are designed in order to improve efficiency of perturbation. Any perturbation based on MOINS and MOEXC takes effect on different criteria simultaneously. The original idea of MOLS is systematic change neighborhoods in the local search procedure. The search direction of MOLS on an individual is naturally guided by interaction of MOINS and MOEXC. Moreover, there is no need to set parameters in MOLS. The MOLS combined with popular multi-objective evolutionary algorithm NSGA-II (Non-dominated Sorting Genetic Algorithm-II) is called as “NSGA-II-MOLS”. To illustrate the efficacy of proposed approach, four different scaled problems are used to test performance of NSGA-II-MOLS. The numerous comparisons show efficacy of NSGA-II-MOLS is better than most of algorithms even with the same number of individual evaluations and parameters setting.

  8. Effective Iterated Greedy Algorithm for Flow-Shop Scheduling Problems with Time lags

    NASA Astrophysics Data System (ADS)

    ZHAO, Ning; YE, Song; LI, Kaidian; CHEN, Siyu

    2017-03-01

    Flow shop scheduling problem with time lags is a practical scheduling problem and attracts many studies. Permutation problem(PFSP with time lags) is concentrated but non-permutation problem(non-PFSP with time lags) seems to be neglected. With the aim to minimize the makespan and satisfy time lag constraints, efficient algorithms corresponding to PFSP and non-PFSP problems are proposed, which consist of iterated greedy algorithm for permutation(IGTLP) and iterated greedy algorithm for non-permutation (IGTLNP). The proposed algorithms are verified using well-known simple and complex instances of permutation and non-permutation problems with various time lag ranges. The permutation results indicate that the proposed IGTLP can reach near optimal solution within nearly 11% computational time of traditional GA approach. The non-permutation results indicate that the proposed IG can reach nearly same solution within less than 1% computational time compared with traditional GA approach. The proposed research combines PFSP and non-PFSP together with minimal and maximal time lag consideration, which provides an interesting viewpoint for industrial implementation.

  9. A hybrid quantum-inspired genetic algorithm for multiobjective flow shop scheduling.

    PubMed

    Li, Bin-Bin; Wang, Ling

    2007-06-01

    This paper proposes a hybrid quantum-inspired genetic algorithm (HQGA) for the multiobjective flow shop scheduling problem (FSSP), which is a typical NP-hard combinatorial optimization problem with strong engineering backgrounds. On the one hand, a quantum-inspired GA (QGA) based on Q-bit representation is applied for exploration in the discrete 0-1 hyperspace by using the updating operator of quantum gate and genetic operators of Q-bit. Moreover, random-key representation is used to convert the Q-bit representation to job permutation for evaluating the objective values of the schedule solution. On the other hand, permutation-based GA (PGA) is applied for both performing exploration in permutation-based scheduling space and stressing exploitation for good schedule solutions. To evaluate solutions in multiobjective sense, a randomly weighted linear-sum function is used in QGA, and a nondominated sorting technique including classification of Pareto fronts and fitness assignment is applied in PGA with regard to both proximity and diversity of solutions. To maintain the diversity of the population, two trimming techniques for population are proposed. The proposed HQGA is tested based on some multiobjective FSSPs. Simulation results and comparisons based on several performance metrics demonstrate the effectiveness of the proposed HQGA.

  10. A new encoding scheme-based hybrid algorithm for minimising two-machine flow-shop group scheduling problem

    NASA Astrophysics Data System (ADS)

    Liou, Cheng-Dar; Hsieh, Yi-Chih; Chen, Yin-Yann

    2013-01-01

    This article investigates the two-machine flow-shop group scheduling problem (GSP) with sequence-dependent setup and removal times, and job transportation times between machines. The objective is to minimise the total completion time. As known, this problem is an NP-hard problem and generalises the typical two-machine GSPs. In this article, a new encoding scheme based on permutation representation is proposed to transform a random job permutation to a feasible permutation for GSPs. The proposed encoding scheme simultaneously determines both the sequence of jobs in each group and the sequence of groups. By reasonably combining particle swarm optimisation (PSO) and genetic algorithm (GA), we develop a fast and easily implemented hybrid algorithm (HA) for solving the considered problems. The effectiveness and efficiency of the proposed HA are demonstrated and compared with those of standard PSO and GA by numerical results of various tested instances with group numbers up to 20. In addition, three different lower bounds are developed to evaluate the solution quality of the HA. Limited numerical results indicate that the proposed HA is a viable and effective approach for the studied two-machine flow-shop group scheduling problem.

  11. An effective PSO-based memetic algorithm for flow shop scheduling.

    PubMed

    Liu, Bo; Wang, Ling; Jin, Yi-Hui

    2007-02-01

    This paper proposes an effective particle swarm optimization (PSO)-based memetic algorithm (MA) for the permutation flow shop scheduling problem (PFSSP) with the objective to minimize the maximum completion time, which is a typical non-deterministic polynomial-time (NP) hard combinatorial optimization problem. In the proposed PSO-based MA (PSOMA), both PSO-based searching operators and some special local searching operators are designed to balance the exploration and exploitation abilities. In particular, the PSOMA applies the evolutionary searching mechanism of PSO, which is characterized by individual improvement, population cooperation, and competition to effectively perform exploration. On the other hand, the PSOMA utilizes several adaptive local searches to perform exploitation. First, to make PSO suitable for solving PFSSP, a ranked-order value rule based on random key representation is presented to convert the continuous position values of particles to job permutations. Second, to generate an initial swarm with certain quality and diversity, the famous Nawaz-Enscore-Ham (NEH) heuristic is incorporated into the initialization of population. Third, to balance the exploration and exploitation abilities, after the standard PSO-based searching operation, a new local search technique named NEH_1 insertion is probabilistically applied to some good particles selected by using a roulette wheel mechanism with a specified probability. Fourth, to enrich the searching behaviors and to avoid premature convergence, a simulated annealing (SA)-based local search with multiple different neighborhoods is designed and incorporated into the PSOMA. Meanwhile, an effective adaptive meta-Lamarckian learning strategy is employed to decide which neighborhood to be used in SA-based local search. Finally, to further enhance the exploitation ability, a pairwise-based local search is applied after the SA-based search. Simulation results based on benchmarks demonstrate the effectiveness

  12. Two Proposed Algorithms for Re-Entrant Flow Shop Problem

    NASA Astrophysics Data System (ADS)

    Abe, Kazumi; Ida, Kenichi

    In a re-entrant flow shop scheduling problem we proposed some algorithms to get a better TAT (turn around time) with a genetic search method. One is an operation which searches for a solution that shifts the start timing in limited areas of each lot. Another is an operation which searches for a solution that shifts left and chooses the machine which starts fastest. Some algorithms are effective on the benchmark including those proposed by Taji et al. In the first step, it is easiest to choose the probabilistic problem by local search. The second step is to search for the solution that shifts the start timing in limited areas of each lot, makes the Gantt chart, chooses the machine and gets the results. The third step is to search for the solution that again shifts left, makes the Gantt chart, chooses the machine and gets the results. The proposed algorithms are more valid than local search methods by Taji et al, such as swap, move, swap-2 neighborhood and FIFO (first in first out). The first algorithm has produced the best result in an experimental test when interval time was short. The second algorithm produced the best result of all solutions. The results have shown that the proposed algorithms are effective for interval time cut and get better TAT than previous methods.

  13. Unfair permutations

    PubMed Central

    Prodinger, Helmut; Schneider, Carsten; Wagner, Stephan

    2011-01-01

    We study unfair permutations, which are generated by letting n players draw numbers and assuming that player i draws i times from the unit interval and records her largest value. This model is natural in the context of partitions: the score of the ith player corresponds to the multiplicity of the summand i in a random partition, with the roles of minimum and maximum interchanged. We study the distribution of several parameters, namely the position of player i, the number of inversions, and the number of ascents. To perform some of the heavy computations, we use the computer algebra package Sigma. PMID:27087722

  14. Multi-objective two-stage multiprocessor flow shop scheduling - a subgroup particle swarm optimisation approach

    NASA Astrophysics Data System (ADS)

    Huang, Rong-Hwa; Yang, Chang-Lin; Hsu, Chun-Ting

    2015-12-01

    Flow shop production system - compared to other economically important production systems - is popular in real manufacturing environments. This study focuses on the flow shop with multiprocessor scheduling problem (FSMP), and develops an improved particle swarm optimisation heuristic to solve it. Additionally, this study designs an integer programming model to perform effectiveness and robustness testing on the proposed heuristic. Experimental results demonstrate a 10% to 50% improvement in the effectiveness of the proposed heuristic in small-scale problem tests, and a 10% to 40% improvement in the robustness of the heuristic in large-scale problem tests, indicating extremely satisfactory performance.

  15. A hybrid water flow algorithm for multi-objective flexible flow shop scheduling problems

    NASA Astrophysics Data System (ADS)

    Hieu Tran, Trung; Ng, Kien Ming

    2013-04-01

    In this article, the multi-objective flexible flow shop scheduling problem with limited intermediate buffers is addressed. The objectives considered in this problem consist of minimizing the completion time of jobs and minimizing the total tardiness time of jobs. A hybrid water flow algorithm for solving this problem is proposed. Landscape analysis is performed to determine the weights of objective functions, which guide the exploration of feasible regions and movement towards the optimal Pareto solution set. Local and global neighbourhood structures are integrated in the erosion process of the algorithm, while evaporation and precipitation processes are included to enhance the solution exploitation capability of the algorithm in unexplored neighbouring regions. An improvement process is used to reinforce the final Pareto solution set obtained. The performance of the proposed algorithm is tested with benchmark and randomly generated instances. The computational results and comparisons demonstrate the effectiveness and efficiency of the proposed algorithm.

  16. Paint shop, coach shop, car shop, and blacksmith shop (all ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Paint shop, coach shop, car shop, and blacksmith shop (all car department), all north of the roadhouse and locomotive shops. Photographed between 1880 and 1888 - Chicago, Burlington & Quincy Railroad, Roundhouse & Shops, Broadway & Spring Streets, Aurora, Kane County, IL

  17. Streaming a single job in a flow shop

    SciTech Connect

    Benli, O.

    1994-12-31

    Very simply stated, lot streaming is moving some portion of a process batch ahead to begin a downstream operation. The problem to be considered in this paper is the following: a single job consisting of U units is to be processed on m machines. Given the maximum number of possible transfer batches in between the machines, the problem is to find the timing and the size of the transfer batches ({open_quotes}sublots{close_quotes}) so as to minimize the makespan. A general formulation of this problem is presented as a mixed integer linear program. This formulation allows for different number of sublots among the stages, variable length sublots, and intermittent idling on a machine. By restricting some of the parameter values (such as m = 2) or the constraints (such as no idling of machines), the well known results from literature can be obtained. The formulation basically is a periodic review model with variable period lengths. Furthermore, the approach is general enough to permit the use of other objective functions such as minimizing the mean flow time (in this case the objective function is quadratic). The possible significance of this generalized approach in the integration of production planning and machine scheduling will be discussed in conclusion.

  18. Entangling power of permutations

    NASA Astrophysics Data System (ADS)

    Clarisse, Lieven; Ghosh, Sibasish; Severini, Simone; Sudbery, Anthony

    2005-07-01

    The notion of entangling power of unitary matrices was introduced by Zanardi , [Phys. Rev. A 62, 030301 (2000)]. We study the entangling power of permutations, given in terms of a combinatorial formula. We show that the permutation matrices with zero entangling power are, up to local unitaries, the identity and the swap. We construct the permutations with the minimum nonzero entangling power for every dimension. With the use of orthogonal latin squares, we construct the permutations with the maximum entangling power for every dimension. Moreover, we show that the value obtained is maximum over all unitaries of the same dimension, with a possible exception for 36. Our result enables us to construct generic examples of 4-qudit maximally entangled states for all dimensions except for 2 and 6. We numerically classify, according to their entangling power, the permutation matrices of dimensions 4 and 9, and we give some estimates for higher dimensions.

  19. Efficient bounding schemes for the two-center hybrid flow shop scheduling problem with removal times.

    PubMed

    Hidri, Lotfi; Gharbi, Anis; Louly, Mohamed Aly

    2014-01-01

    We focus on the two-center hybrid flow shop scheduling problem with identical parallel machines and removal times. The job removal time is the required duration to remove it from a machine after its processing. The objective is to minimize the maximum completion time (makespan). A heuristic and a lower bound are proposed for this NP-Hard problem. These procedures are based on the optimal solution of the parallel machine scheduling problem with release dates and delivery times. The heuristic is composed of two phases. The first one is a constructive phase in which an initial feasible solution is provided, while the second phase is an improvement one. Intensive computational experiments have been conducted to confirm the good performance of the proposed procedures.

  20. Three-Stage Tabu Search for Solving Large-Scale Flow Shop Scheduling Problems

    NASA Astrophysics Data System (ADS)

    Xu, Yuedong; Tian, Yajie; Sannomiya, Nobuo

    Tabu search is a meta-heuristic approach designed skillfully for finding a suboptimal solution of combinatorial optimization problems. In this paper the tabu search with three stages is proposed for solving large-scale flow shop scheduling problems. In order to obtain a better suboptimal solution in a short computation time, three different candidate lists are used to determine the incumbent solution in the respective search stages. The candidate lists are constructed by restricting the moving of each job. Test problems with four kinds of job data are examined. Based on analyzing the relationship between the candidate list and the suboptimal solution for each job data, a common parameter is given to construct the candidate list during the search process. Comparison of the computation result is made with the genetic algorithm and the basic tabu search, from which it is shown that the proposed tabu search outperforms two others.

  1. A comparison of rescheduling policies for online flow shops to minimize tardiness

    NASA Astrophysics Data System (ADS)

    Tokola, Henri; Ahlroth, Lauri; Niemi, Esko

    2014-02-01

    In practical situations, flow shops usually have some policies on rescheduling previously scheduled jobs. This article compares three of these rescheduling policies: an unrestricted one where previously scheduled jobs can be moved freely, one where jobs can only be moved forward in the schedule, and one where jobs that have already been scheduled cannot be moved at all. The comparison is performed by considering the minimization of tardiness. While unrestricted rescheduling should generally give the best solution, moving jobs only forward can be more practical as in general production, material orders can be delayed but seldom advanced. This article points out that moving jobs only forward is not significantly worse than the unrestricted scheduling. When cases with small numbers of jobs and machines are analysed both policies give similar tardiness. Numerical experiments show that the differences between these two rescheduling policies are rather small in larger problems as well.

  2. Scheduling of flow shop problems on 3 machines in fuzzy environment with double transport facility

    NASA Astrophysics Data System (ADS)

    Sathish, Shakeela; Ganesan, K.

    2016-06-01

    Flow shop scheduling is a decision making problem in production and manufacturing field which has a significant impact on the performance of an organization. When the machines on which jobs are to be processed are placed at different places, the transportation time plays a significant role in production. Further two different transport agents where 1st takes the job from 1st machine to 2nd machine and then returns back to the first machine and the 2nd takes the job from 2nd machine to 3rd machine and then returns back to the 2nd machine are also considered. We propose a method to minimize the total make span; without converting the fuzzy processing time to classical numbers by using a new type of fuzzy arithmetic and a fuzzy ranking method. A numerical example is provided to explain the proposed method.

  3. Two-machine flow shop scheduling integrated with preventive maintenance planning

    NASA Astrophysics Data System (ADS)

    Wang, Shijin; Liu, Ming

    2016-02-01

    This paper investigates an integrated optimisation problem of production scheduling and preventive maintenance (PM) in a two-machine flow shop with time to failure of each machine subject to a Weibull probability distribution. The objective is to find the optimal job sequence and the optimal PM decisions before each job such that the expected makespan is minimised. To investigate the value of integrated scheduling solution, computational experiments on small-scale problems with different configurations are conducted with total enumeration method, and the results are compared with those of scheduling without maintenance but with machine degradation, and individual job scheduling combined with independent PM planning. Then, for large-scale problems, four genetic algorithm (GA) based heuristics are proposed. The numerical results with several large problem sizes and different configurations indicate the potential benefits of integrated scheduling solution and the results also show that proposed GA-based heuristics are efficient for the integrated problem.

  4. Linear models: permutation methods

    USGS Publications Warehouse

    Cade, B.S.; Everitt, B.S.; Howell, D.C.

    2005-01-01

    Permutation tests (see Permutation Based Inference) for the linear model have applications in behavioral studies when traditional parametric assumptions about the error term in a linear model are not tenable. Improved validity of Type I error rates can be achieved with properly constructed permutation tests. Perhaps more importantly, increased statistical power, improved robustness to effects of outliers, and detection of alternative distributional differences can be achieved by coupling permutation inference with alternative linear model estimators. For example, it is well-known that estimates of the mean in linear model are extremely sensitive to even a single outlying value of the dependent variable compared to estimates of the median [7, 19]. Traditionally, linear modeling focused on estimating changes in the center of distributions (means or medians). However, quantile regression allows distributional changes to be estimated in all or any selected part of a distribution or responses, providing a more complete statistical picture that has relevance to many biological questions [6]...

  5. A multi-objective scatter search for a bi-criteria no-wait flow shop scheduling problem

    NASA Astrophysics Data System (ADS)

    Rahimi-Vahed, A. R.; Javadi, B.; Rabbani, M.; Tavakkoli-Moghaddam, R.

    2008-04-01

    The flow shop problem as a typical manufacturing challenge has gained wide attention in academic fields. This article considers a bi-criteria no-wait flow shop scheduling problem (FSSP) in which weighted mean completion time and weighted mean tardiness are to be minimized simultaneously. Since a FSSP has been proved to be NP-hard in a strong sense, a new multi-objective scatter search (MOSS) is designed for finding the locally Pareto-optimal frontier of the problem. To prove the efficiency of the proposed algorithm, various test problems are solved and the reliability of the proposed algorithm, based on some comparison metrics, is compared with a distinguished multi-objective genetic algorithm (GA), i.e. SPEA-II. The computational results show that the proposed MOSS performs better than the above GA, especially for the large-sized problems.

  6. Scheduling algorithm for flow shop with two batch-processing machines and arbitrary job sizes

    NASA Astrophysics Data System (ADS)

    Cheng, Bayi; Yang, Shanlin; Hu, Xiaoxuan; Li, Kai

    2014-03-01

    This article considers the problem of scheduling two batch-processing machines in flow shop where the jobs have arbitrary sizes and the machines have limited capacity. The jobs are processed in batches and the total size of jobs in each batch cannot exceed the machine capacity. Once a batch is being processed, no interruption is allowed until all the jobs in it are completed. The problem of minimising makespan is NP-hard in the strong sense. First, we present a mathematical model of the problem using integer programme. We show the scale of feasible solutions of the problem and provide optimality properties. Then, we propose a polynomial time algorithm with running time in O(nlogn). The jobs are first assigned in feasible batches and then scheduled on machines. For the general case, we prove that the proposed algorithm has a performance guarantee of 4. For the special case where the processing times of each job on the two machines satisfy p 1 j = ap 2 j , the performance guarantee is ? for a > 0.

  7. Hardware Index to Permutation Converter

    DTIC Science & Technology

    2012-05-01

    Hardware Index to Permutation Converter J. T. Butler T. Sasao Department of Electrical and Computer Engineering Department of Computer Science...generates a permutation in response to an index. Since there are n! n-element permutations , the index ranges from 0 to n! − 1. Such a circuit is needed...in the hardware implementation of unique- permutation hash functions to specify how parallel machines interact through a shared memory. Such a circuit

  8. Asymptotic analysis of SPTA-based algorithms for no-wait flow shop scheduling problem with release dates.

    PubMed

    Ren, Tao; Zhang, Chuan; Lin, Lin; Guo, Meiting; Xie, Xionghang

    2014-01-01

    We address the scheduling problem for a no-wait flow shop to optimize total completion time with release dates. With the tool of asymptotic analysis, we prove that the objective values of two SPTA-based algorithms converge to the optimal value for sufficiently large-sized problems. To further enhance the performance of the SPTA-based algorithms, an improvement scheme based on local search is provided for moderate scale problems. New lower bound is presented for evaluating the asymptotic optimality of the algorithms. Numerical simulations demonstrate the effectiveness of the proposed algorithms.

  9. Visual recognition of permuted words

    NASA Astrophysics Data System (ADS)

    Rashid, Sheikh Faisal; Shafait, Faisal; Breuel, Thomas M.

    2010-02-01

    In current study we examine how letter permutation affects in visual recognition of words for two orthographically dissimilar languages, Urdu and German. We present the hypothesis that recognition or reading of permuted and non-permuted words are two distinct mental level processes, and that people use different strategies in handling permuted words as compared to normal words. A comparison between reading behavior of people in these languages is also presented. We present our study in context of dual route theories of reading and it is observed that the dual-route theory is consistent with explanation of our hypothesis of distinction in underlying cognitive behavior for reading permuted and non-permuted words. We conducted three experiments in lexical decision tasks to analyze how reading is degraded or affected by letter permutation. We performed analysis of variance (ANOVA), distribution free rank test, and t-test to determine the significance differences in response time latencies for two classes of data. Results showed that the recognition accuracy for permuted words is decreased 31% in case of Urdu and 11% in case of German language. We also found a considerable difference in reading behavior for cursive and alphabetic languages and it is observed that reading of Urdu is comparatively slower than reading of German due to characteristics of cursive script.

  10. Tetrachoric Correlation: A Permutation Alternative

    ERIC Educational Resources Information Center

    Long, Michael A.; Berry, Kenneth J.; Mielke, Paul W., Jr.

    2009-01-01

    An exact permutation test is provided for the tetrachoric correlation coefficient. Comparisons with the conventional test employing Student's t distribution demonstrate the necessity of using the permutation approach for small sample sizes and/or disproportionate marginal frequency totals. (Contains 4 tables.)

  11. Stochastic flow shop scheduling of overlapping jobs on tandem machines in application to optimizing the US Army's deliberate nuclear, biological, and chemical decontamination process, (final report). Master's thesis

    SciTech Connect

    Novikov, V.

    1991-05-01

    The U.S. Army's detailed equipment decontamination process is a stochastic flow shop which has N independent non-identical jobs (vehicles) which have overlapping processing times. This flow shop consists of up to six non-identical machines (stations). With the exception of one station, the processing times of the jobs are random variables. Based on an analysis of the processing times, the jobs for the 56 Army heavy division companies were scheduled according to the best shortest expected processing time - longest expected processing time (SEPT-LEPT) sequence. To assist in this scheduling the Gap Comparison Heuristic was developed to select the best SEPT-LEPT schedule. This schedule was then used in balancing the detailed equipment decon line in order to find the best possible site configuration subject to several constraints. The detailed troop decon line, in which all jobs are independent and identically distributed, was then balanced. Lastly, an NBC decon optimization computer program was developed using the scheduling and line balancing results. This program serves as a prototype module for the ANBACIS automated NBC decision support system.... Decontamination, Stochastic flow shop, Scheduling, Stochastic scheduling, Minimization of the makespan, SEPT-LEPT Sequences, Flow shop line balancing, ANBACIS.

  12. Asymptotic analysis of online algorithms and improved scheme for the flow shop scheduling problem with release dates

    NASA Astrophysics Data System (ADS)

    Bai, Danyu

    2015-08-01

    This paper discusses the flow shop scheduling problem to minimise the total quadratic completion time (TQCT) with release dates in offline and online environments. For this NP-hard problem, the investigation is focused on the performance of two online algorithms based on the Shortest Processing Time among Available jobs rule. Theoretical results indicate the asymptotic optimality of the algorithms as the problem scale is sufficiently large. To further enhance the quality of the original solutions, the improvement scheme is provided for these algorithms. A new lower bound with performance guarantee is provided, and computational experiments show the effectiveness of these heuristics. Moreover, several results of the single-machine TQCT problem with release dates are also obtained for the deduction of the main theorem.

  13. An effective shuffled frog-leaping algorithm for solving the hybrid flow-shop scheduling problem with identical parallel machines

    NASA Astrophysics Data System (ADS)

    Xu, Ye; Wang, Ling; Wang, Shengyao; Liu, Min

    2013-12-01

    In this article, an effective shuffled frog-leaping algorithm (SFLA) is proposed to solve the hybrid flow-shop scheduling problem with identical parallel machines (HFSP-IPM). First, some novel heuristic decoding rules for both job order decision and machine assignment are proposed. Then, three hybrid decoding schemes are designed to decode job order sequences to schedules. A special bi-level crossover and multiple local search operators are incorporated in the searching framework of the SFLA to enrich the memetic searching behaviour and to balance the exploration and exploitation capabilities. Meanwhile, some theoretical analysis for the local search operators is provided for guiding the local search. The parameter setting of the algorithm is also investigated based on the Taguchi method of design of experiments. Finally, numerical testing based on well-known benchmarks and comparisons with some existing algorithms are carried out to demonstrate the effectiveness of the proposed algorithm.

  14. Permutations and time series analysis.

    PubMed

    Cánovas, Jose S; Guillamón, Antonio

    2009-12-01

    The main aim of this paper is to show how the use of permutations can be useful in the study of time series analysis. In particular, we introduce a test for checking the independence of a time series which is based on the number of admissible permutations on it. The main improvement in our tests is that we are able to give a theoretical distribution for independent time series.

  15. Doctor Shopping

    PubMed Central

    Sansone, Lori A.

    2012-01-01

    Doctor shopping is defined as seeing multiple treatment providers, either during a single illness episode or to procure prescription medications illicitly. According to the available literature, prevalence rates of doctor shopping vary widely, from 6.3 to 56 percent. However, this variability is partially attributable to research methodology, including the study definition of doctor shopping as well as the patient sample. The reasons for doctor shopping are varied. Some patient explanations for this phenomenon relate to clinician factors, such as inconvenient office hours or locations, long waiting times, personal characteristics or qualities of the provider, and/or insufficient communication time between the patient and clinician. Some patient explanations relate to personal factors and include both illness factors (e.g., symptom persistence, lack of understanding or nonacceptance of the diagnosis or treatment) as well as psychological factors (e.g., somatization, prescription drug-seeking). Importantly, not all doctor shopping is driven by suspect motivations. Being aware of these various patient justifications for doctor shopping is important in understanding and managing these challenging patients in the clinical setting, whether they emerge in psychiatric or primary care environments. PMID:23346518

  16. A discrete artificial bee colony algorithm incorporating differential evolution for the flow-shop scheduling problem with blocking

    NASA Astrophysics Data System (ADS)

    Han, Yu-Yan; Gong, Dunwei; Sun, Xiaoyan

    2015-07-01

    A flow-shop scheduling problem with blocking has important applications in a variety of industrial systems but is underrepresented in the research literature. In this study, a novel discrete artificial bee colony (ABC) algorithm is presented to solve the above scheduling problem with a makespan criterion by incorporating the ABC with differential evolution (DE). The proposed algorithm (DE-ABC) contains three key operators. One is related to the employed bee operator (i.e. adopting mutation and crossover operators of discrete DE to generate solutions with good quality); the second is concerned with the onlooker bee operator, which modifies the selected solutions using insert or swap operators based on the self-adaptive strategy; and the last is for the local search, that is, the insert-neighbourhood-based local search with a small probability is adopted to improve the algorithm's capability in exploitation. The performance of the proposed DE-ABC algorithm is empirically evaluated by applying it to well-known benchmark problems. The experimental results show that the proposed algorithm is superior to the compared algorithms in minimizing the makespan criterion.

  17. Explorations in Statistics: Permutation Methods

    ERIC Educational Resources Information Center

    Curran-Everett, Douglas

    2012-01-01

    Learning about statistics is a lot like learning about science: the learning is more meaningful if you can actively explore. This eighth installment of "Explorations in Statistics" explores permutation methods, empiric procedures we can use to assess an experimental result--to test a null hypothesis--when we are reluctant to trust statistical…

  18. Novel permutation measures for image encryption algorithms

    NASA Astrophysics Data System (ADS)

    Abd-El-Hafiz, Salwa K.; AbdElHaleem, Sherif H.; Radwan, Ahmed G.

    2016-10-01

    This paper proposes two measures for the evaluation of permutation techniques used in image encryption. First, a general mathematical framework for describing the permutation phase used in image encryption is presented. Using this framework, six different permutation techniques, based on chaotic and non-chaotic generators, are described. The two new measures are, then, introduced to evaluate the effectiveness of permutation techniques. These measures are (1) Percentage of Adjacent Pixels Count (PAPC) and (2) Distance Between Adjacent Pixels (DBAP). The proposed measures are used to evaluate and compare the six permutation techniques in different scenarios. The permutation techniques are applied on several standard images and the resulting scrambled images are analyzed. Moreover, the new measures are used to compare the permutation algorithms on different matrix sizes irrespective of the actual parameters used in each algorithm. The analysis results show that the proposed measures are good indicators of the effectiveness of the permutation technique.

  19. Shop Projects.

    ERIC Educational Resources Information Center

    Patton, Bob

    Vocational agriculture teachers in Oklahoma prepared the shop project drawings which comprise the document. Seventy-one projects, with lists of required materials, diagrams, and measurements, are included. Construction projects fall into six categories (number of projects in parentheses): Trailers (5), racks (3), livestock production projects…

  20. g_permute: Permutation-reduced phase space density compaction

    NASA Astrophysics Data System (ADS)

    Reinhard, F.; Lange, O. F.; Hub, J. S.; Haas, J.; Grubmüller, H.

    2009-03-01

    Biomolecular processes are governed by free energy changes and thus depend on a fine-tuned interplay between entropy and enthalpy. To calculate accurate values for entropies from simulations is particularly challenging for the solvation shell of proteins, which contributes crucially to the total entropy of solvated proteins, due to the diffusive motion of the solvent molecules. Accordingly, for each frame of a Molecular dynamics (MD) trajectory, our software relabels the solvent molecules, such that the resulting configuration space volume is reduced by a factor of N! with N being the number of solvent molecules. The combinatorial explosion of a naive implementation is here overcome by transforming the task into a linear assignment problem, for which algorithms with complexity O(N) exist. We have shown in previous research that the solvent entropy can be estimated from such a compacted trajectory by established entropy estimation methods. In this paper, we describe the software implementation which also allows applications beyond entropy estimation, such as the permutation of lipids in membrane bilayers. Program summaryProgram title: g_permute Catalogue identifier: AECJ_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AECJ_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: GPL No. of lines in distributed program, including test data, etc.: 45 173 No. of bytes in distributed program, including test data, etc.: 2 730 678 Distribution format: tar.gz Programming language: C Computer: PC-compatible running Linux Operating system: Linux RAM: Dependent on the number of solvent molecules, min 12 582 912 bytes Classification: 3, 4.8, 4.9 External routines: liblap (included); From GROMACS-3.3.1: libgmx (not included) Nature of problem: Estimating the entropy of solvent molecules from a molecular dynamics simulation trajectory cannot be performed on ordinary trajectories. Solution method: Compacting

  1. Circular permutant GFP insertion folding reporters

    SciTech Connect

    Waldo, Geoffrey S.; Cabantous, Stephanie

    2013-04-16

    Provided are methods of assaying and improving protein folding using circular permutants of fluorescent proteins, including circular permutants of GFP variants and combinations thereof. The invention further provides various nucleic acid molecules and vectors incorporating such nucleic acid molecules, comprising polynucleotides encoding fluorescent protein circular permutants derived from superfolder GFP, which polynucleotides include an internal cloning site into which a heterologous polynucleotide may be inserted in-frame with the circular permutant coding sequence, and which when expressed are capable of reporting on the degree to which a polypeptide encoded by such an inserted heterologous polynucleotide is correctly folded by correlation with the degree of fluorescence exhibited.

  2. Circular permutant GFP insertion folding reporters

    DOEpatents

    Waldo, Geoffrey S.; Cabantous, Stephanie

    2008-06-24

    Provided are methods of assaying and improving protein folding using circular permutants of fluorescent proteins, including circular permutants of GFP variants and combinations thereof. The invention further provides various nucleic acid molecules and vectors incorporating such nucleic acid molecules, comprising polynucleotides encoding fluorescent protein circular permutants derived from superfolder GFP, which polynucleotides include an internal cloning site into which a heterologous polynucleotide may be inserted in-frame with the circular permutant coding sequence, and which when expressed are capable of reporting on the degree to which a polypeptide encoded by such an inserted heterologous polynucleotide is correctly folded by correlation with the degree of fluorescence exhibited.

  3. Circular permutant GFP insertion folding reporters

    DOEpatents

    Waldo, Geoffrey S; Cabantous, Stephanie

    2013-02-12

    Provided are methods of assaying and improving protein folding using circular permutants of fluorescent proteins, including circular permutants of GFP variants and combinations thereof. The invention further provides various nucleic acid molecules and vectors incorporating such nucleic acid molecules, comprising polynucleotides encoding fluorescent protein circular permutants derived from superfolder GFP, which polynucleotides include an internal cloning site into which a heterologous polynucleotide may be inserted in-frame with the circular permutant coding sequence, and which when expressed are capable of reporting on the degree to which a polypeptide encoded by such an inserted heterologous polynucleotide is correctly folded by correlation with the degree of fluorescence exhibited.

  4. Circular permutant GFP insertion folding reporters

    DOEpatents

    Waldo, Geoffrey S.; Cabantous, Stephanie

    2011-06-14

    Provided are methods of assaying and improving protein folding using circular permutants of fluorescent proteins, including circular permutants of GFP variants and combinations thereof. The invention further provides various nucleic acid molecules and vectors incorporating such nucleic acid molecules, comprising polynucleotides encoding fluorescent protein circular permutants derived from superfolder GFP, which polynucleotides include an internal cloning site into which a heterologous polynucleotide may be inserted in-frame with the circular permutant coding sequence, and which when expressed are capable of reporting on the degree to which a polypeptide encoded by such an inserted heterologous polynucleotide is correctly folded by correlation with the degree of fluorescence exhibited.

  5. Healthy grocery shopping

    MedlinePlus

    ... medlineplus.gov/ency/patientinstructions/000336.htm Healthy grocery shopping To use the sharing features on this page, ... a conscious decision about eating that food. Smart Shopping Avoid buying snack foods in bulk and shopping ...

  6. 14. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific Railroad Carlin Shops, view to north (90mm lens). - Southern Pacific Railroad, Carlin Shops, Roundhouse Machine Shop Extension, Foot of Sixth Street, Carlin, Elko County, NV

  7. Permutation symmetry for theta functions

    SciTech Connect

    Carlson, B.C.

    2011-01-21

    This paper does for combinations of theta functions most of what Carlson (2004) [1] did for Jacobian elliptic functions. In each case the starting point is the symmetric elliptic integral R{sub F} of the first kind. Its three arguments (formerly squared Jacobian elliptic functions but now squared combinations of theta functions) differ by constants. Symbols designating the constants can often be used to replace 12 equations by three with permutation symmetry (formerly in the letters c, d, n for the Jacobian case but now in the subscripts 2, 3, 4 for theta functions). Such equations include derivatives and differential equations, bisection and duplication relations, addition formulas (apparently new for theta functions), and an example of pseudoaddition formulas.

  8. Permutation parity machines for neural cryptography

    SciTech Connect

    Reyes, Oscar Mauricio; Zimmermann, Karl-Heinz

    2010-06-15

    Recently, synchronization was proved for permutation parity machines, multilayer feed-forward neural networks proposed as a binary variant of the tree parity machines. This ability was already used in the case of tree parity machines to introduce a key-exchange protocol. In this paper, a protocol based on permutation parity machines is proposed and its performance against common attacks (simple, geometric, majority and genetic) is studied.

  9. Permutation parity machines for neural cryptography.

    PubMed

    Reyes, Oscar Mauricio; Zimmermann, Karl-Heinz

    2010-06-01

    Recently, synchronization was proved for permutation parity machines, multilayer feed-forward neural networks proposed as a binary variant of the tree parity machines. This ability was already used in the case of tree parity machines to introduce a key-exchange protocol. In this paper, a protocol based on permutation parity machines is proposed and its performance against common attacks (simple, geometric, majority and genetic) is studied.

  10. Permutation parity machines for neural cryptography

    NASA Astrophysics Data System (ADS)

    Reyes, Oscar Mauricio; Zimmermann, Karl-Heinz

    2010-06-01

    Recently, synchronization was proved for permutation parity machines, multilayer feed-forward neural networks proposed as a binary variant of the tree parity machines. This ability was already used in the case of tree parity machines to introduce a key-exchange protocol. In this paper, a protocol based on permutation parity machines is proposed and its performance against common attacks (simple, geometric, majority and genetic) is studied.

  11. AUTOMOTIVE REPAIR SHOP, INTERIOR VIEW TO SOUTHEAST, DOORWAYS TO SHOP ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    AUTOMOTIVE REPAIR SHOP, INTERIOR VIEW TO SOUTHEAST, DOORWAYS TO SHOP OFFICE AND SOUTH WING, WITH SCALE. - Cedar City Automotive Repair Shop, Automotive Repair Shop, 820 North Main Street, Cedar City, Iron County, UT

  12. AUTOMOTIVE REPAIR SHOP, INTERIOR VIEW TO SOUTHEAST, DOORWAYS TO SHOP ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    AUTOMOTIVE REPAIR SHOP, INTERIOR VIEW TO SOUTHEAST, DOORWAYS TO SHOP OFFICE AND SOUTH WING. - Cedar City Automotive Repair Shop, Automotive Repair Shop, 820 North Main Street, Cedar City, Iron County, UT

  13. Blocks in cycles and k-commuting permutations.

    PubMed

    Moreno, Rutilo; Rivera, Luis Manuel

    2016-01-01

    We introduce and study k-commuting permutations. One of our main results is a characterization of permutations that k-commute with a given permutation. Using this characterization, we obtain formulas for the number of permutations that k-commute with a permutation [Formula: see text], for some cycle types of [Formula: see text]. Our enumerative results are related with integer sequences in "The On-line Encyclopedia of Integer Sequences", and in some cases provide new interpretations for such sequences.

  14. 16. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific Railroad Carlin Shops, view to south (90mm lens). Note the large segmental-arched doorway to move locomotives in and out of Machine Shop. - Southern Pacific Railroad, Carlin Shops, Roundhouse Machine Shop Extension, Foot of Sixth Street, Carlin, Elko County, NV

  15. A hybrid job-shop scheduling system

    NASA Technical Reports Server (NTRS)

    Hellingrath, Bernd; Robbach, Peter; Bayat-Sarmadi, Fahid; Marx, Andreas

    1992-01-01

    The intention of the scheduling system developed at the Fraunhofer-Institute for Material Flow and Logistics is the support of a scheduler working in a job-shop. Due to the existing requirements for a job-shop scheduling system the usage of flexible knowledge representation and processing techniques is necessary. Within this system the attempt was made to combine the advantages of symbolic AI-techniques with those of neural networks.

  16. Flavour singlets in gauge theory as permutations

    NASA Astrophysics Data System (ADS)

    Kimura, Yusuke; Ramgoolam, Sanjaye; Suzuki, Ryo

    2016-12-01

    Gauge-invariant operators can be specified by equivalence classes of permutations. We develop this idea concretely for the singlets of the flavour group SO( N f ) in U( N c ) gauge theory by using Gelfand pairs and Schur-Weyl duality. The singlet operators, when specialised at N f = 6, belong to the scalar sector of N=4 SYM. A simple formula is given for the two-point functions in the free field limit of g Y M 2 = 0. The free two-point functions are shown to be equal to the partition function on a 2-complex with boundaries and a defect, in a topological field theory of permutations. The permutation equivalence classes are Fourier transformed to a representation basis which is orthogonal for the two-point functions at finite N c , N f . Counting formulae for the gauge-invariant operators are described. The one-loop mixing matrix is derived as a linear operator on the permutation equivalence classes.

  17. Permutation Tests for Common Locations among Samples with Unequal Variances.

    ERIC Educational Resources Information Center

    Mielke, Paul W., Jr.; Berry, Kenneth J.

    1994-01-01

    Presents permutation procedures that jointly test for differences in location and scale among treatments in a completely randomized experimental design. Also considers extensions to multivariate data and provides efficient alternative permutation tests. (SLD)

  18. Demonstration of quantum permutation algorithm with a single photon ququart.

    PubMed

    Wang, Feiran; Wang, Yunlong; Liu, Ruifeng; Chen, Dongxu; Zhang, Pei; Gao, Hong; Li, Fuli

    2015-06-05

    We report an experiment to demonstrate a quantum permutation determining algorithm with linear optical system. By employing photon's polarization and spatial mode, we realize the quantum ququart states and all the essential permutation transformations. The quantum permutation determining algorithm displays the speedup of quantum algorithm by determining the parity of the permutation in only one step of evaluation compared with two for classical algorithm. This experiment is accomplished in single photon level and the method exhibits universality in high-dimensional quantum computation.

  19. The organization of permutation architectures with bussed interconnections

    NASA Astrophysics Data System (ADS)

    Kilian, Joe; Kipnis, Sholomo; Leiserson, Charles E.

    1989-01-01

    The problem of efficiently permuting data stored in VLSI chips is explored in accordance with a predetermined set of permutations. By connecting chips with shared bus interconnections, as opposed to point-to-point interconnections, it is shown that the number of pins per chip can often be reduced. Uniform permutation architectures were also considered that realize permutations in several clock ticks, instead of one, and show that further savings in the number of pins per chip can be obtained.

  20. The organization of permutation architectures with bused interconnections

    NASA Astrophysics Data System (ADS)

    Kilian, Joe; Kipnis, Shlomo; Leiserson, Charles E.

    1990-11-01

    The problem of efficiently permuting data stored in VLSI chips is explored, in accordance with a predetermined set of permutations. By connecting chips with shared bus interconnections, as opposed to point-to-point interconnections, it is shown that the number of pins per chip can often be reduced. Uniform permutation architectures are also considered that realize permutations in several clock ticks, instead of one, and it is demonstrated that further savings in the number of pins per chip can be obtained.

  1. Permutation-invariant codes encoding more than one qubit

    NASA Astrophysics Data System (ADS)

    Ouyang, Yingkai; Fitzsimons, Joseph

    2016-04-01

    A permutation-invariant code on m qubits is a subspace of the symmetric subspace of the m qubits. We derive permutation-invariant codes that can encode an increasing amount of quantum information while suppressing leading-order spontaneous decay errors. To prove the result, we use elementary number theory with prior theory on permutation-invariant codes and quantum error correction.

  2. Section Looking North, Blacksmith Shop; South Elevation, Blacksmith Shop ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Section Looking North, Blacksmith Shop; South Elevation, Blacksmith Shop - Central of Georgia Railway, Savannah Repair Shops & Terminal Facilities, Bounded by West Broad, Jones, West Boundary & Hull Streets, Savannah, Chatham County, GA

  3. 6. NORTH END OF MACHINE SHOP. FORGE SHOP (HAER No. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. NORTH END OF MACHINE SHOP. FORGE SHOP (HAER No. CA-326-K) ON LEFT, FORD PLANT IN DISTANCE, NE BY 60. - Rosie the Riveter National Historical Park, Machine Shop, 1311 Canal Boulevard, Richmond, Contra Costa County, CA

  4. Erection Shop, west elevation (left) and Boiler & Tank Shop, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Erection Shop, west elevation (left) and Boiler & Tank Shop, east and north elevations (right). - Pittsburgh & Lake Erie Railroad, Locomotive Repair Shops, River Road at Chartiers Avenue, McKees Rocks, Allegheny County, PA

  5. Technicians and Shop Owners

    EPA Pesticide Factsheets

    Overview page provides information for shops and technicians that repair or service motor vehicle air-conditioning systems, including information on proper training, approved equipment, and regulatory practices.

  6. Eyes wide shopped: shopping situations trigger arousal in impulsive buyers.

    PubMed

    Serfas, Benjamin G; Büttner, Oliver B; Florack, Arnd

    2014-01-01

    The present study proposes arousal as an important mechanism driving buying impulsiveness. We examined the effect of buying impulsiveness on arousal in non-shopping and shopping contexts. In an eye-tracking experiment, we measured pupil dilation while participants viewed and rated pictures of shopping scenes and non-shopping scenes. The results demonstrated that buying impulsiveness is closely associated with arousal as response to viewing pictures of shopping scenes. This pertained for hedonic shopping situations as well as for utilitarian shopping situations. Importantly, the effect did not emerge for non-shopping scenes. Furthermore, we demonstrated that arousal of impulsive buyers is independent from cognitive evaluation of scenes in the pictures.

  7. Inference for Distributions over the Permutation Group

    DTIC Science & Technology

    2008-05-01

    studied distributions over permu-tations/rankings ( Mallows , 1957; Crit hlow, 1985; Fligner & Verdu i, 1986;Taylor et al., 2008; Lebanon & Mao, 2008...on distan e based models. For ex-ample, the Mallows model ( Mallows , 1957) denes a Gaussian-like distributionover permutations as: P (σ; c, σ0) ∝ exp...partially ranked) data based onpla ing weighted Mallows kernels on top of training examples, whi h, as theyshow, an realize a far ri her lass of

  8. Report Card. Learn & Shop.

    ERIC Educational Resources Information Center

    Indiana Univ.-Purdue Univ., Indianapolis.

    The Indiana University-Purdue University at Indianapolis'"Learn & Shop" program, which offers regular college credit courses in convenient shopping centers, is discussed. In addition to providing information on students, books and libraries, curriculum, and classes, consideration is given to advantages for students, retailers, and…

  9. Machine Shop Lathes.

    ERIC Educational Resources Information Center

    Dunn, James

    This guide, the second in a series of five machine shop curriculum manuals, was designed for use in machine shop courses in Oklahoma. The purpose of the manual is to equip students with basic knowledge and skills that will enable them to enter the machine trade at the machine-operator level. The curriculum is designed so that it can be used in…

  10. Shopping. Teaching Guide.

    ERIC Educational Resources Information Center

    Florida Univ., Gainesville. Florida Cooperative Extension Service.

    One in a series of consumer education materials for 4-H Club members and secondary students, this document focuses on shopping and purchasing. The series is based on the philosophy that teens need the training and guidance to develop the skills needed to become competent consumers. The shopping project is designed to acquaint students with some of…

  11. Neighbourhood generation mechanism applied in simulated annealing to job shop scheduling problems

    NASA Astrophysics Data System (ADS)

    Cruz-Chávez, Marco Antonio

    2015-11-01

    This paper presents a neighbourhood generation mechanism for the job shop scheduling problems (JSSPs). In order to obtain a feasible neighbour with the generation mechanism, it is only necessary to generate a permutation of an adjacent pair of operations in a scheduling of the JSSP. If there is no slack time between the adjacent pair of operations that is permuted, then it is proven, through theory and experimentation, that the new neighbour (schedule) generated is feasible. It is demonstrated that the neighbourhood generation mechanism is very efficient and effective in a simulated annealing.

  12. 20. MACHINE SHOP, LOOKING SOUTH. SHOP IS EQUIPPED WITH A ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. MACHINE SHOP, LOOKING SOUTH. SHOP IS EQUIPPED WITH A 25-TON SHAW CRANE TO HANDLE PARTS FROM RAIL CARS INTO THE SHOP. MACHINE SHOP HANDLES ALL NECESSARY REPAIR WORK ON THE DOCK MACHINERY. - Pennsylvania Railway Ore Dock, Lake Erie at Whiskey Island, approximately 1.5 miles west of Public Square, Cleveland, Cuyahoga County, OH

  13. Genome Reshuffling for Advanced Intercross Permutation (GRAIP): Simulation and permutation for advanced intercross population analysis

    SciTech Connect

    Pierce, Jeremy; Broman, Karl; Lu, Lu; Chesler, Elissa J; Zhou, Guomin; Airey, David; Birmingham, Amanda; Williams, Robert

    2008-04-01

    Background: Advanced intercross lines (AIL) are segregating populations created using a multi-generation breeding protocol for fine mapping complex trait loci (QTL) in mice and other organisms. Applying QTL mapping methods for intercross and backcross populations, often followed by na ve permutation of individuals and phenotypes, does not account for the effect of AIL family structure in which final generations have been expanded and leads to inappropriately low significance thresholds. The critical problem with na ve mapping approaches in AIL populations is that the individual is not an exchangeable unit. Methodology/Principal Findings: The effect of family structure has immediate implications for the optimal AIL creation (many crosses, few animals per cross, and population expansion before the final generation) and we discuss these and the utility of AIL populations for QTL fine mapping. We also describe Genome Reshuffling for Advanced Intercross Permutation, (GRAIP) a method for analyzing AIL data that accounts for family structure. GRAIP permutes a more interchangeable unit in the final generation crosses - the parental genome - and simulating regeneration of a permuted AIL population based on exchanged parental identities. GRAIP determines appropriate genome-wide significance thresholds and locus-specific Pvalues for AILs and other populations with similar family structures. We contrast GRAIP with na ve permutation using a large densely genotyped mouse AIL population (1333 individuals from 32 crosses). A na ve permutation using coat color as a model phenotype demonstrates high false-positive locus identification and uncertain significance levels, which are corrected using GRAIP. GRAIP also detects an established hippocampus weight locus and a new locus, Hipp9a. Conclusions and Significance: GRAIP determines appropriate genome-wide significance thresholds and locus-specific Pvalues for AILs and other populations with similar family structures. The effect of

  14. Mercury Shopping Cart Interface

    NASA Technical Reports Server (NTRS)

    Pfister, Robin; McMahon, Joe

    2006-01-01

    Mercury Shopping Cart Interface (MSCI) is a reusable component of the Power User Interface 5.0 (PUI) program described in another article. MSCI is a means of encapsulating the logic and information needed to describe an orderable item consistent with Mercury Shopping Cart service protocol. Designed to be used with Web-browser software, MSCI generates Hypertext Markup Language (HTML) pages on which ordering information can be entered. MSCI comprises two types of Practical Extraction and Report Language (PERL) modules: template modules and shopping-cart logic modules. Template modules generate HTML pages for entering the required ordering details and enable submission of the order via a Hypertext Transfer Protocol (HTTP) post. Shopping cart modules encapsulate the logic and data needed to describe an individual orderable item to the Mercury Shopping Cart service. These modules evaluate information entered by the user to determine whether it is sufficient for the Shopping Cart service to process the order. Once an order has been passed from MSCI to a deployed Mercury Shopping Cart server, there is no further interaction with the user.

  15. 15. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific Railroad Carlin Shops, view to northeast (90mm lens). The arched cutouts in the bottom chords of the roof trusses were necessary to provide clearance for the smokestacks of steam locomotives, and also mark the location of the former inspection pit in the floor (now filled in and covered by a new concrete floor). - Southern Pacific Railroad, Carlin Shops, Roundhouse Machine Shop Extension, Foot of Sixth Street, Carlin, Elko County, NV

  16. Online shopping hesitation.

    PubMed

    Cho, Chang-Hoan; Kang, Jaewon; Cheon, Hongsik John

    2006-06-01

    This study was designed to understand which factors influence consumer hesitation or delay in online product purchases. The study examined four groups of variables (i.e., consumer characteristics, contextual factors perceived uncertainty factors, and medium/channel innovation factors) that predict three types of online shopping hesitation (i.e., overall hesitation, shopping cart abandonment, and hesitation at the final payment stage). We found that different sets of delay factors are related to different aspects of online shopping hesitation. The study concludes with suggestion for various delay-reduction devices to help consumers close their online decision hesitation.

  17. Remodeling A School Shop?

    ERIC Educational Resources Information Center

    Baker, G. E.

    1970-01-01

    Presents guidelines for remodeling a school shop combining major considerations of funds, program changes, class management, and flexibility, with the needs of wiring, painting, and placement of equipment. (Author)

  18. Shopping for Funeral Services

    MedlinePlus

    ... Funeral July 2012 Search form Search menu Money & Credit Shopping & Saving "Free" Trial Offers? 'Bamboo' Fabrics 10 ... You Are Here Bookmark Buying & Owning a Car Credit & Loans Dealing with Debt Resolving Consumer Problems Homes & ...

  19. Space Odyssey Gift Shop

    NASA Technical Reports Server (NTRS)

    2000-01-01

    The Space Odyssey Gift Shop located in StenniSphere at the John C. Stennis Space Center in Hancock County, Miss., offers every visitor the opportunity to go home with 'the right stuff' from his or her StenniSphere visit. The gift shop is located just inside the front doors to StenniSphere and offers a wide range of space-related apparel, memorabilia, toys, books, mission patches and more.

  20. Space Odyssey Gift Shop

    NASA Technical Reports Server (NTRS)

    2000-01-01

    The Space Odyssey Gift Shop located in StenniSphere at the John C. Stennis Space Center in Hancock County, Miss., offers every visitor the opportunity to go home with 'the right stuff' from his or her StenniSphere visit. The gift shop is located just inside the front doors to StenniSphere and offers a wide range of space-related apparel, memorabilia, toys, books, mission patches and more.

  1. Weight distributions for turbo codes using random and nonrandom permutations

    NASA Technical Reports Server (NTRS)

    Dolinar, S.; Divsalar, D.

    1995-01-01

    This article takes a preliminary look at the weight distributions achievable for turbo codes using random, nonrandom, and semirandom permutations. Due to the recursiveness of the encoders, it is important to distinguish between self-terminating and non-self-terminating input sequences. The non-self-terminating sequences have little effect on decoder performance, because they accumulate high encoded weight until they are artificially terminated at the end of the block. From probabilistic arguments based on selecting the permutations randomly, it is concluded that the self-terminating weight-2 data sequences are the most important consideration in the design of constituent codes; higher-weight self-terminating sequences have successively decreasing importance. Also, increasing the number of codes and, correspondingly, the number of permutations makes it more and more likely that the bad input sequences will be broken up by one or more of the permuters. It is possible to design nonrandom permutations that ensure that the minimum distance due to weight-2 input sequences grows roughly as the square root of (2N), where N is the block length. However, these nonrandom permutations amplify the bad effects of higher-weight inputs, and as a result they are inferior in performance to randomly selected permutations. But there are 'semirandom' permutations that perform nearly as well as the designed nonrandom permutations with respect to weight-2 input sequences and are not as susceptible to being foiled by higher-weight inputs.

  2. Permutation-invariant distance between atomic configurations.

    PubMed

    Ferré, Grégoire; Maillet, Jean-Bernard; Stoltz, Gabriel

    2015-09-14

    We present a permutation-invariant distance between atomic configurations, defined through a functional representation of atomic positions. This distance enables us to directly compare different atomic environments with an arbitrary number of particles, without going through a space of reduced dimensionality (i.e., fingerprints) as an intermediate step. Moreover, this distance is naturally invariant through permutations of atoms, avoiding the time consuming associated minimization required by other common criteria (like the root mean square distance). Finally, the invariance through global rotations is accounted for by a minimization procedure in the space of rotations solved by Monte Carlo simulated annealing. A formal framework is also introduced, showing that the distance we propose verifies the property of a metric on the space of atomic configurations. Two examples of applications are proposed. The first one consists in evaluating faithfulness of some fingerprints (or descriptors), i.e., their capacity to represent the structural information of a configuration. The second application concerns structural analysis, where our distance proves to be efficient in discriminating different local structures and even classifying their degree of similarity.

  3. Permutation-invariant distance between atomic configurations

    SciTech Connect

    Ferré, Grégoire; Maillet, Jean-Bernard; Stoltz, Gabriel

    2015-09-14

    We present a permutation-invariant distance between atomic configurations, defined through a functional representation of atomic positions. This distance enables us to directly compare different atomic environments with an arbitrary number of particles, without going through a space of reduced dimensionality (i.e., fingerprints) as an intermediate step. Moreover, this distance is naturally invariant through permutations of atoms, avoiding the time consuming associated minimization required by other common criteria (like the root mean square distance). Finally, the invariance through global rotations is accounted for by a minimization procedure in the space of rotations solved by Monte Carlo simulated annealing. A formal framework is also introduced, showing that the distance we propose verifies the property of a metric on the space of atomic configurations. Two examples of applications are proposed. The first one consists in evaluating faithfulness of some fingerprints (or descriptors), i.e., their capacity to represent the structural information of a configuration. The second application concerns structural analysis, where our distance proves to be efficient in discriminating different local structures and even classifying their degree of similarity.

  4. Genome Reshuffling for Advanced Intercross Permutation (GRAIP): Simulation and permutation for advanced intercross population analysis

    SciTech Connect

    Pierce, Jeremy; Broman, Karl; Chesler, Elissa J; Zhou, Guomin; Airey, David; Birmingham, Amanda; Williams, Robert

    2008-01-01

    Abstract Background Advanced intercross lines (AIL) are segregating populations created using a multigeneration breeding protocol for fine mapping complex traits in mice and other organisms. Applying quantitative trait locus (QTL) mapping methods for intercross and backcross populations, often followed by na ve permutation of individuals and phenotypes, does not account for the effect of family structure in AIL populations in which final generations have been expanded and leads to inappropriately low significance thresholds. The critical problem with a na ve mapping approach in such AIL populations is that the individual is not an exchangeable unit given the family structure. Methodology/Principal Findings The effect of family structure has immediate implications for the optimal AIL creation (many crosses, few animals per cross, and population expansion before the final generation) and we discuss these and the utility of AIL populations for QTL fine mapping. We also describe Genome Reshuffling for Advanced Intercross Permutation, (GRAIP) a method for analyzing AIL data that accounts for family structure. RAIP permutes a more interchangeable unit in the final generation crosses - the parental genome - and simulating regeneration of a permuted AIL population based on exchanged parental identities. GRAIP determines appropriate genome- ide significance thresholds and locus-specific P-values for AILs and other populations with similar family structures. We contrast GRAIP with na ve permutation using a large densely genotyped mouse AIL population (1333 individuals from 32 crosses). A na ve permutation using coat color as a model phenotype demonstrates high false-positive locus identification and uncertain significance levels in our AIL population, which are corrected by use of GRAIP. We also show that GRAIP detects an established hippocampus weight locus and a new locus, Hipp9a. Conclusions and Significance GRAIP determines appropriate genome-wide significance thresholds

  5. 158. BLACKSMITH SHOP, DRIVE SHAFT FOR BLACKSMITH AND WOOD SHOPS. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    158. BLACKSMITH SHOP, DRIVE SHAFT FOR BLACKSMITH AND WOOD SHOPS. BELT ON RIGHT POWERS GRUBER BUILT BELT SANDER. - Gruber Wagon Works, Pennsylvania Route 183 & State Hill Road at Red Bridge Park, Bernville, Berks County, PA

  6. Eyes Wide Shopped: Shopping Situations Trigger Arousal in Impulsive Buyers

    PubMed Central

    Serfas, Benjamin G.; Büttner, Oliver B.; Florack, Arnd

    2014-01-01

    The present study proposes arousal as an important mechanism driving buying impulsiveness. We examined the effect of buying impulsiveness on arousal in non-shopping and shopping contexts. In an eye-tracking experiment, we measured pupil dilation while participants viewed and rated pictures of shopping scenes and non-shopping scenes. The results demonstrated that buying impulsiveness is closely associated with arousal as response to viewing pictures of shopping scenes. This pertained for hedonic shopping situations as well as for utilitarian shopping situations. Importantly, the effect did not emerge for non-shopping scenes. Furthermore, we demonstrated that arousal of impulsive buyers is independent from cognitive evaluation of scenes in the pictures. PMID:25489955

  7. 42. MACHINE SHOP Machine shop area with small parts bins ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    42. MACHINE SHOP Machine shop area with small parts bins on the right and pipe storage racks on the left. Remains of the power drive system are suspended from the ceiling. - Hovden Cannery, 886 Cannery Row, Monterey, Monterey County, CA

  8. Application of half butterfly method in listing permutation

    NASA Astrophysics Data System (ADS)

    Karim, Sharmila; Darus, Maizon Mohd; Ibrahim, Haslinda

    2016-10-01

    A Half Butterfly Method is a new method introduced to construct the distinct circuits in complete graphs where used the concept of isomorphism. The Half Butterfly Method can be applied in the field of combinatorics such as in listing permutations of n elements. Thus, in this paper, we presented a permutation generation using Half Butterfly Method.

  9. Overall interior view of structures shop (11 shop) located on ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Overall interior view of structures shop (11 shop) located on west side of building 57 - looking north; the south end of the structures shop was devoted to welding heavy plate foundations and ship components; the floor is fabricated of case steel and features a grillwork of 1 1/2 fabricated holes which are used as sockets for gripping position pins. - Naval Base Philadelphia-Philadelphia Naval Shipyard, Structure Shop, League Island, Philadelphia, Philadelphia County, PA

  10. A Fuzzy Permutation Method for False Discovery Rate Control.

    PubMed

    Yang, Ya-Hui; Lin, Wan-Yu; Lee, Wen-Chung

    2016-06-22

    Biomedical researchers often encounter the large-p-small-n situations-a great number of variables are measured/recorded for only a few subjects. The authors propose a fuzzy permutation method to address the multiple testing problem for small sample size studies. The method introduces fuzziness into standard permutation analysis to produce randomized p-values, which are then converted into q-values for false discovery rate controls. Simple algebra shows that the fuzzy permutation method is at least as powerful as the standard permutation method under any alternative. Monte-Carlo simulations show that the proposed method has desirable statistical properties whether the study variables are normally or non-normally distributed. A real dataset is analyzed to illustrate its use. The proposed fuzzy permutation method is recommended for use in the large-p-small-n settings.

  11. Permutation importance: a corrected feature importance measure.

    PubMed

    Altmann, André; Toloşi, Laura; Sander, Oliver; Lengauer, Thomas

    2010-05-15

    In life sciences, interpretability of machine learning models is as important as their prediction accuracy. Linear models are probably the most frequently used methods for assessing feature relevance, despite their relative inflexibility. However, in the past years effective estimators of feature relevance have been derived for highly complex or non-parametric models such as support vector machines and RandomForest (RF) models. Recently, it has been observed that RF models are biased in such a way that categorical variables with a large number of categories are preferred. In this work, we introduce a heuristic for normalizing feature importance measures that can correct the feature importance bias. The method is based on repeated permutations of the outcome vector for estimating the distribution of measured importance for each variable in a non-informative setting. The P-value of the observed importance provides a corrected measure of feature importance. We apply our method to simulated data and demonstrate that (i) non-informative predictors do not receive significant P-values, (ii) informative variables can successfully be recovered among non-informative variables and (iii) P-values computed with permutation importance (PIMP) are very helpful for deciding the significance of variables, and therefore improve model interpretability. Furthermore, PIMP was used to correct RF-based importance measures for two real-world case studies. We propose an improved RF model that uses the significant variables with respect to the PIMP measure and show that its prediction accuracy is superior to that of other existing models. R code for the method presented in this article is available at http://www.mpi-inf.mpg.de/ approximately altmann/download/PIMP.R CONTACT: altmann@mpi-inf.mpg.de, laura.tolosi@mpi-inf.mpg.de Supplementary data are available at Bioinformatics online.

  12. VIEW SOUTHCENTERBUILDING 61 CARPENTER SHOP (1911) RIGHTBUILDING 32 MACHINE SHOP ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW SOUTH-CENTER-BUILDING 61 CARPENTER SHOP (1911) RIGHT-BUILDING 32 MACHINE SHOP (1890) LEFT-BUILDING 42 ROPE SHOP (1910) - John A. Roebling's Sons Company & American Steel & Wire Company, South Broad, Clark, Elmer, Mott & Hudson Streets, Trenton, Mercer County, NJ

  13. General view along tracks to Locomotive Shop with Car Shop ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view along tracks to Locomotive Shop with Car Shop on right. Note locomotive tires leaning against Car Shop wall. View from west - East Broad Top Railroad & Coal Company, State Route 994, West of U.S. Route 522, Rockhill Furnace, Huntingdon County, PA

  14. 5. Machine shop and air brake shop sections of roundhouse ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Machine shop and air brake shop sections of roundhouse in background. Foundry (MN-99-B) in foreground. View to south. - Duluth & Iron Range Rail Road Company Shops, Roundhouse, Southwest of downtown Two Harbors, northwest of Agate Bay, Two Harbors, Lake County, MN

  15. Interior of girder shop, from older section of shop showing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior of girder shop, from older section of shop showing older (1880's) construction of roof trusses. Compare with earlier views in this series. - Phoenix Iron Company, Girder Shop No. 6, North of French Creek, west of Gay Street, Phoenixville, Chester County, PA

  16. View north of inside machine shop 36; shop floor accommodates ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View north of inside machine shop 36; shop floor accommodates lathes capable of machining a cylinder 60 inches in diameter and 75 feet long; other equipment includes horizontal and vertical jig borders, hydraulic tube straighteners and other equipment for precision machining of large ship components. - Naval Base Philadelphia-Philadelphia Naval Shipyard, Structure Shop, League Island, Philadelphia, Philadelphia County, PA

  17. Modified permutation-entropy analysis of heartbeat dynamics.

    PubMed

    Bian, Chunhua; Qin, Chang; Ma, Qianli D Y; Shen, Qinghong

    2012-02-01

    Heart rate variability (HRV) contains important information about the modulation of the cardiovascular system. Various methods of nonlinear dynamics (e.g., estimating Lyapunov exponents) and complexity measures (e.g., correlation dimension or entropies) have been applied to HRV analysis. Permutation entropy, which was proposed recently, has been widely used in many fields due to its conceptual and computational simplicity. It maps a time series onto a symbolic sequence of permutation ranks. The original permutation entropy assumes the time series under study has a continuous distribution, thus equal values are rare and can be ignored by ranking them according to their order of emergence, or broken by adding small random perturbations to ensure every symbol in a sequence is different. However, when the observed time series is digitized with lower resolution leading to a greater number of equal values, or the equalities represent certain characteristic sequential patterns of the system, it may not be rational to simply ignore or break them. In the present paper, a modified permutation entropy is proposed that, by mapping the equal value onto the same symbol (rank), allows for a more accurate characterization of system states. The application of the modified permutation entropy to the analysis of HRV is investigated using clinically collected data. Results show that modified permutation entropy can greatly improve the ability to distinguish the HRV signals under different physiological and pathological conditions. It can characterize the complexity of HRV more effectively than the original permutation entropy.

  18. Modified permutation-entropy analysis of heartbeat dynamics

    NASA Astrophysics Data System (ADS)

    Bian, Chunhua; Qin, Chang; Ma, Qianli D. Y.; Shen, Qinghong

    2012-02-01

    Heart rate variability (HRV) contains important information about the modulation of the cardiovascular system. Various methods of nonlinear dynamics (e.g., estimating Lyapunov exponents) and complexity measures (e.g., correlation dimension or entropies) have been applied to HRV analysis. Permutation entropy, which was proposed recently, has been widely used in many fields due to its conceptual and computational simplicity. It maps a time series onto a symbolic sequence of permutation ranks. The original permutation entropy assumes the time series under study has a continuous distribution, thus equal values are rare and can be ignored by ranking them according to their order of emergence, or broken by adding small random perturbations to ensure every symbol in a sequence is different. However, when the observed time series is digitized with lower resolution leading to a greater number of equal values, or the equalities represent certain characteristic sequential patterns of the system, it may not be rational to simply ignore or break them. In the present paper, a modified permutation entropy is proposed that, by mapping the equal value onto the same symbol (rank), allows for a more accurate characterization of system states. The application of the modified permutation entropy to the analysis of HRV is investigated using clinically collected data. Results show that modified permutation entropy can greatly improve the ability to distinguish the HRV signals under different physiological and pathological conditions. It can characterize the complexity of HRV more effectively than the original permutation entropy.

  19. Machine Shop Grinding Machines.

    ERIC Educational Resources Information Center

    Dunn, James

    This curriculum manual is one in a series of machine shop curriculum manuals intended for use in full-time secondary and postsecondary classes, as well as part-time adult classes. The curriculum can also be adapted to open-entry, open-exit programs. Its purpose is to equip students with basic knowledge and skills that will enable them to enter the…

  20. The Micro-Shop.

    ERIC Educational Resources Information Center

    Steele, Barbara

    1992-01-01

    To reduce teacher isolation and encourage sharing of expertise, schools should consider brief workshops or 15-minute "micro-shops" on various topics ranging from making electrical circuit boards to setting up a salt-water aquarium. This article and accompanying sidebar discuss benefits and set-up strategies. (MLH)

  1. The Mobile Costume Shop.

    ERIC Educational Resources Information Center

    Witherspoon, Cindy; Nelson, Steve

    1998-01-01

    Discusses the difficulties of costume construction for high school theater productions. Advances a plan (and provides a design) for a mobile costume shop which contains the basic needs of a functional costume facility, using only 60 square feet of space. Lists every element and implement needed. (PA)

  2. Discrete phase-space mappings, tomographic condition and permutation invariance

    NASA Astrophysics Data System (ADS)

    Muñoz, C.; Klimov, A. B.

    2017-04-01

    We analyze various families of discrete maps in N-qubit systems in the context of permutation invariance. We prove that the tomographic condition imposed on the self-dual (Wigner) map is incompatible with the requirement of the invariance under particle permutations (except for the two-qubit case), which makes it impossible to project the Wootters-like Wigner function into the space of symmetric measurements. We also provide several explicit forms of the self-dual mappings: (a) tomographic and (b) permutation invariant, and analyze the symmetric projection in the latter case.

  3. Multiscale permutation entropy analysis of electrocardiogram

    NASA Astrophysics Data System (ADS)

    Liu, Tiebing; Yao, Wenpo; Wu, Min; Shi, Zhaorong; Wang, Jun; Ning, Xinbao

    2017-04-01

    To make a comprehensive nonlinear analysis to ECG, multiscale permutation entropy (MPE) was applied to ECG characteristics extraction to make a comprehensive nonlinear analysis of ECG. Three kinds of ECG from PhysioNet database, congestive heart failure (CHF) patients, healthy young and elderly subjects, are applied in this paper. We set embedding dimension to 4 and adjust scale factor from 2 to 100 with a step size of 2, and compare MPE with multiscale entropy (MSE). As increase of scale factor, MPE complexity of the three ECG signals are showing first-decrease and last-increase trends. When scale factor is between 10 and 32, complexities of the three ECG had biggest difference, entropy of the elderly is 0.146 less than the CHF patients and 0.025 larger than the healthy young in average, in line with normal physiological characteristics. Test results showed that MPE can effectively apply in ECG nonlinear analysis, and can effectively distinguish different ECG signals.

  4. Permutation method for evaluating topographic craniofacial correlations.

    PubMed

    Halazonetis, Demetrios J

    2011-03-01

    Correlations between cephalometric measurements are frequently assumed to represent biologic associations. However, a significant portion of such correlations might arise from purely geometric dependencies, when measurements share common landmarks. Analytic calculation of this topographic component is difficult. The purpose of this study was to propose a permutation method for evaluating the topographic component of cephalometric correlations. The method consisted of creating a virtual sample of cephalometric tracings (landmark configurations) from the original biologic sample under investigation. Each novel landmark configuration was constructed by assigning coordinates to the cephalometric points; the coordinates of each point were taken randomly from the original sample, each from a potentially different subject. Correlation analysis was performed separately on both samples and the results compared. Biologic meaning was ascribed only when there was a significant difference in correlation values between the samples. Confidence intervals for assessing statistical significance were calculated by using a randomization approach. The method was tested on a sample of 170 radiographs to evaluate the correlation between cranial base angle (NSBa) and angles SNA and SNB, as well as between ANB angle and the Wits appraisal. No biologic association was found between ANB and Wits, or between NSBa and SNA. The biologic correlation between NSBa and SNB was statistically significant but low (r(2) = 12%). Topographic associations between cephalometric measurements are ubiquitous and difficult to assess. The proposed method enables evaluation of their relative strength without the need for analytic solutions. Copyright © 2011 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  5. Permutation centralizer algebras and multimatrix invariants

    NASA Astrophysics Data System (ADS)

    Mattioli, Paolo; Ramgoolam, Sanjaye

    2016-03-01

    We introduce a class of permutation centralizer algebras which underly the combinatorics of multimatrix gauge-invariant observables. One family of such noncommutative algebras is parametrized by two integers. Its Wedderburn-Artin decomposition explains the counting of restricted Schur operators, which were introduced in the physics literature to describe open strings attached to giant gravitons and were subsequently used to diagonalize the Gaussian inner product for gauge invariants of two-matrix models. The structure of the algebra, notably its dimension, its center and its maximally commuting subalgebra, is related to Littlewood-Richardson numbers for composing Young diagrams. It gives a precise characterization of the minimal set of charges needed to distinguish arbitrary matrix gauge invariants, which are related to enhanced symmetries in gauge theory. The algebra also gives a star product for matrix invariants. The center of the algebra allows efficient computation of a sector of multimatrix correlators. These generate the counting of a certain class of bicoloured ribbon graphs with arbitrary genus.

  6. Differentiating Climatic Variability with Multi - Permutation Procedures

    NASA Astrophysics Data System (ADS)

    Law-Evans, Elizabeth

    It is hypothesized that a Multi-Response Permutation Procedure (MRPP) can be developed which can detect changes in natural time series. A companion hypothesis is that climatic and hydrologic changes have occurred in historical time in watersheds in Colorado and northern New Mexico. The non-parametric nature of MRPP precludes normality assumptions required by many techniques. The MRPP technique was applied to historical climatic and hydrologic time series (annual air temperature and snowfall; annual and monthly precipitation and streamflow). A variation of the MRPP technique was adapted, termed "moving-MRPP". The moving-MRPP marched the MRPP analyses through the series in a fashion similar to a moving average. The use of non-normal values brought about the greatest improvement between the results from the moving -MRPP technique with a distance exponent of one (v = 1) and the squared distance exponent (v = 2; used in "normal" or "classical" statistics such as standard deviation). Using moving-MRPP as an exploratory technique, seven meteorological and two streamflow sites in Colorado and New Mexico were studied. Analysis of the sites' historical records suggested region-wide changes in variability during the period of record which agreed with published dates and types of changes in hemispheric circulation regimes. Two changes in variability are especially noticeable: first, a period of low climatic variability from the early 1920s to the mid 1950s. Second, a period of highly variable conditions from the mid 1970s to 1986.

  7. Optical brush: Imaging through permuted probes

    PubMed Central

    Heshmat, Barmak; Lee, Ik Hyun; Raskar, Ramesh

    2016-01-01

    The combination of computational techniques and ultrafast imaging have enabled sensing through unconventional settings such as around corners, and through diffusive media. We exploit time of flight (ToF) measurements to enable a flexible interface for imaging through permuted set of fibers. The fibers are randomly distributed in the scene and are packed on the camera end, thus making a brush-like structure. The scene is illuminated by two off-axis optical pulses. Temporal signatures of fiber tips in the scene are used to localize each fiber. Finally, by combining the position and measured intensity of each fiber, the original input is reconstructed. Unlike conventional fiber bundles with packed set of fibers that are limited by a narrow field of view (FOV), lack of flexibility, and extended coaxial precalibration, the proposed optical brush is flexible and uses off-axis calibration method based on ToF. The enabled brush form can couple to other types of ToF imaging systems. This can impact probe-based applications such as, endoscopy, tomography, and industrial imaging and sensing. PMID:26868954

  8. Image encryption using a synchronous permutation-diffusion technique

    NASA Astrophysics Data System (ADS)

    Enayatifar, Rasul; Abdullah, Abdul Hanan; Isnin, Ismail Fauzi; Altameem, Ayman; Lee, Malrey

    2017-03-01

    In the past decade, the interest on digital images security has been increased among scientists. A synchronous permutation and diffusion technique is designed in order to protect gray-level image content while sending it through internet. To implement the proposed method, two-dimensional plain-image is converted to one dimension. Afterward, in order to reduce the sending process time, permutation and diffusion steps for any pixel are performed in the same time. The permutation step uses chaotic map and deoxyribonucleic acid (DNA) to permute a pixel, while diffusion employs DNA sequence and DNA operator to encrypt the pixel. Experimental results and extensive security analyses have been conducted to demonstrate the feasibility and validity of this proposed image encryption method.

  9. Dynamic Permutational Isomerism in a closo-Cluster.

    PubMed

    Fu, Junhong; Morshedi, Mahbod; Moxey, Graeme J; Barlow, Adam; Cifuentes, Marie P; Humphrey, Mark G

    2016-04-04

    Permutational isomers of trigonal bipyramidal [W2RhIr2(CO)9(η(5)-C5H5)2(η(5)-C5HMe4)] result from competitive capping of either a W2Ir or a WIr2 face of the tetrahedral cluster [W2Ir2(CO)10(η(5)-C5 H5)2] from its reaction with [Rh(CO)2(η(5)-C5HMe4)]. The permutational isomers slowly interconvert in solution by a cluster metal vertex exchange that is proposed to proceed by Rh-Ir and Rh-W bond cleavage and reformation, and via the intermediacy of an edge-bridged tetrahedral transition state. The permutational isomers display differing chemical and physical properties: replacement of CO by PPh3 occurs at one permutational isomer only, while the isomers display distinct optical power limiting behavior. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. A Random Variable Related to the Inversion Vector of a Partial Random Permutation

    ERIC Educational Resources Information Center

    Laghate, Kavita; Deshpande, M. N.

    2005-01-01

    In this article, we define the inversion vector of a permutation of the integers 1, 2,..., n. We set up a particular kind of permutation, called a partial random permutation. The sum of the elements of the inversion vector of such a permutation is a random variable of interest.

  11. A Random Variable Related to the Inversion Vector of a Partial Random Permutation

    ERIC Educational Resources Information Center

    Laghate, Kavita; Deshpande, M. N.

    2005-01-01

    In this article, we define the inversion vector of a permutation of the integers 1, 2,..., n. We set up a particular kind of permutation, called a partial random permutation. The sum of the elements of the inversion vector of such a permutation is a random variable of interest.

  12. A hyper-chaos-based image encryption algorithm using pixel-level permutation and bit-level permutation

    NASA Astrophysics Data System (ADS)

    Li, Yueping; Wang, Chunhua; Chen, Hua

    2017-03-01

    Recently, a number of chaos-based image encryption algorithms that use low-dimensional chaotic map and permutation-diffusion architecture have been proposed. However, low-dimensional chaotic map is less safe than high-dimensional chaotic system. And permutation process is independent of plaintext and diffusion process. Therefore, they cannot resist efficiently the chosen-plaintext attack and chosen-ciphertext attack. In this paper, we propose a hyper-chaos-based image encryption algorithm. The algorithm adopts a 5-D multi-wing hyper-chaotic system, and the key stream generated by hyper-chaotic system is related to the original image. Then, pixel-level permutation and bit-level permutation are employed to strengthen security of the cryptosystem. Finally, a diffusion operation is employed to change pixels. Theoretical analysis and numerical simulations demonstrate that the proposed algorithm is secure and reliable for image encryption.

  13. Effluent minimization: Metal finishing shop

    SciTech Connect

    1988-12-31

    A metal finishing job shop reduced rinsewater volume and ensured compliance with discharge regulations by installing a staged rinse system, segregating waste streams, and modifying processing solutions.

  14. Autobody Refinishing General Best Shop Practices

    EPA Pesticide Factsheets

    This document focuses on the key components of beneficial change in small auto refinish shops. Compiled from real-life shop experiences, the documents serve as worker protection and pollution prevention goals for the small shop.

  15. Realization of Meander Permutations by Boundary Value Problems

    NASA Astrophysics Data System (ADS)

    Fiedler, Bernold; Rocha, Carlos

    1999-08-01

    We consider Neumann boundary value problems of the form uxx+f(x, u, ux)=0 on the unit interval 0⩽x⩽1 for a certain class of dissipative nonlinearities f. Associated to these problems we have (i) meanders in the phase space (u, ux)∈R2, which are connected oriented simple curves on the plane intersecting a fixed oriented line (the u-axis) in n points corresponding to the solutions; and (ii) meander permutations πf∈S(n) obtained by ordering the intersection points first along the u-axis and then along the meander. The meander permutation πf is the permutation defined by the braid of solutions in the space (x, u, ux). It was recently shown by Fiedler and Rocha that πf determines the global attractor of the dynamical system generated by the semilinear parabolic differential equation ut=uxx+f(x, u, ux), up to C0 orbit equivalence. Therefore, these permutations are of considerable importance in the classification problem of the (Morse-Smale) attractors for these dynamical systems. In this paper we present a purely combinatorial characterization of the set of meander permutations that are realizable by the above boundary value problems.

  16. Extended precedence preservative crossover for job shop scheduling problems

    NASA Astrophysics Data System (ADS)

    Ong, Chung Sin; Moin, Noor Hasnah; Omar, Mohd

    2013-04-01

    Job shop scheduling problems (JSSP) is one of difficult combinatorial scheduling problems. A wide range of genetic algorithms based on the two parents crossover have been applied to solve the problem but multi parents (more than two parents) crossover in solving the JSSP is still lacking. This paper proposes the extended precedence preservative crossover (EPPX) which uses multi parents for recombination in the genetic algorithms. EPPX is a variation of the precedence preservative crossover (PPX) which is one of the crossovers that perform well to find the solutions for the JSSP. EPPX is based on a vector to determine the gene selected in recombination for the next generation. Legalization of children (offspring) can be eliminated due to the JSSP representation encoded by using permutation with repetition that guarantees the feasibility of chromosomes. The simulations are performed on a set of benchmarks from the literatures and the results are compared to ensure the sustainability of multi parents recombination in solving the JSSP.

  17. Product Searching with Shopping Bots.

    ERIC Educational Resources Information Center

    Rowley, Jennifer

    2000-01-01

    Using trial searches for three best-selling books, this study examined the search facilities offered by shopping bots, which support consumers with the product search and identification stage in e-shopping. Findings indicate that effectiveness of bots not only depends upon search facilities but also upon product coverage, and other added value…

  18. Machine Shop: Scope and Sequence.

    ERIC Educational Resources Information Center

    Nashville - Davidson County Metropolitan Public Schools, TN.

    Intended for use by all machine shop instructors in the Metropolitan Nashville Public Schools, this guide provides a sequential listing of course content and scope. A course description provides a brief overview of the content of the courses offered in the machine shop program. General course objectives are then listed. Outlines of the course…

  19. Product Searching with Shopping Bots.

    ERIC Educational Resources Information Center

    Rowley, Jennifer

    2000-01-01

    Using trial searches for three best-selling books, this study examined the search facilities offered by shopping bots, which support consumers with the product search and identification stage in e-shopping. Findings indicate that effectiveness of bots not only depends upon search facilities but also upon product coverage, and other added value…

  20. Differential Validities For Shop Courses.

    ERIC Educational Resources Information Center

    Lokan, Janice J.; Halpern, Gerald

    In a vocational high school in Ottawa, Canada, with an enrollment of approximately 750 students, 25 different shop courses are available. Students must take six shop courses during the first year, then specialize in two during the second year. During the first 2 years of operation, between two-thirds and three-fourths of those enrolled requested…

  1. AAFES Shopping Center Environmental Assessment

    DTIC Science & Technology

    2009-08-01

    AFB, Montana. February. _________. 2006c. Malmstrom Air Force Base Runoff Curve Numbers, Time of Concentration, Peak Discharge. Report Prepared...The existing Base Exchange was constructed in 1957 and the building suffers from dated design features that limit retail merchandising...proposes to construct a new Shopping Center at Malmstrom Air Force Base (AFB), Montana. The Shopping Center would feature retail and food

  2. 6. VIEW WESTINTERIOR OF BOILER SHOP SECTION OF THE BETHLEHEM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. VIEW WEST-INTERIOR OF BOILER SHOP SECTION OF THE BETHLEHEM STEEL COMPANY SHIPYARD BLACKSMITH SHOP/BOILER SHOP. - Bethlehem Steel Company Shipyard, Blacksmith Shop-Boiler Shop, 1201-1321 Hudson Street, Hoboken, Hudson County, NJ

  3. 3. VIEW SOUTHNORTH ELEVATION OF BLACKSMITH SHOP SECTION OF THE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. VIEW SOUTH-NORTH ELEVATION OF BLACKSMITH SHOP SECTION OF THE BETHLEHEM STEEL COMPANY SHIPYARD BLACKSMITH SHOP/BOILER SHOP. - Bethlehem Steel Company Shipyard, Blacksmith Shop-Boiler Shop, 1201-1321 Hudson Street, Hoboken, Hudson County, NJ

  4. 2. VIEW SOUTHWESTNORTH ELEVATION OF BOILER SHOP SECTION OF THE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. VIEW SOUTHWEST-NORTH ELEVATION OF BOILER SHOP SECTION OF THE BETHLEHEM STEEL COMPANY SHIPYARD BLACKSMITH SHOP/BOILER SHOP. - Bethlehem Steel Company Shipyard, Blacksmith Shop-Boiler Shop, 1201-1321 Hudson Street, Hoboken, Hudson County, NJ

  5. 8. VIEW EASTINTERIOR OF BLACKSMITH SHOP SECTION OF THE BETHLEM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. VIEW EAST-INTERIOR OF BLACKSMITH SHOP SECTION OF THE BETHLEM STEEL COMPANY SHIPYARD BLACKSMITH SHOP/BOILER SHOP. - Bethlehem Steel Company Shipyard, Blacksmith Shop-Boiler Shop, 1201-1321 Hudson Street, Hoboken, Hudson County, NJ

  6. 7. VIEW EASTINTERIOR OF BOILER SHOP SECTION OF THE BETHLEHEM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. VIEW EAST-INTERIOR OF BOILER SHOP SECTION OF THE BETHLEHEM STEEL COMPANY SHIPYARD BLACKSMITH SHOP/BOILER SHOP. - Bethlehem Steel Company Shipyard, Blacksmith Shop-Boiler Shop, 1201-1321 Hudson Street, Hoboken, Hudson County, NJ

  7. 9. VIEW WESTINTERIOR OF BLACKSMITH SHOP SECTION OF THE BETHLEHEM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. VIEW WEST-INTERIOR OF BLACKSMITH SHOP SECTION OF THE BETHLEHEM STEEL COMPANY SHIPYARD BLACKSMITH SHOP/BOILER SHOP. - Bethlehem Steel Company Shipyard, Blacksmith Shop-Boiler Shop, 1201-1321 Hudson Street, Hoboken, Hudson County, NJ

  8. A permutation characterization of Sturm global attractors of Hamiltonian type

    NASA Astrophysics Data System (ADS)

    Fiedler, Bernold; Rocha, Carlos; Wolfrum, Matthias

    We consider Neumann boundary value problems of the form u=u+f on the interval 0⩽x⩽π for dissipative nonlinearities f=f(u). A permutation characterization for the global attractors of the semiflows generated by these equations is well known, even in the much more general case f=f(x,u,u). We present a permutation characterization for the global attractors in the restrictive class of nonlinearities f=f(u). In this class the stationary solutions of the parabolic equation satisfy the second order ODE v+f(v)=0 and we obtain the permutation characterization from a characterization of the set of 2 π-periodic orbits of this planar Hamiltonian system. Our results are based on a diligent discussion of this mere pendulum equation.

  9. Forbidden patterns, permutation entropy and stock market inefficiency

    NASA Astrophysics Data System (ADS)

    Zunino, Luciano; Zanin, Massimiliano; Tabak, Benjamin M.; Pérez, Darío G.; Rosso, Osvaldo A.

    2009-07-01

    In this paper we introduce two new quantifiers for the stock market inefficiency: the number of forbidden patterns and the normalized permutation entropy. They are model-independent measures, thus they have more general applicability. We find robust evidence that degree of market inefficiency is positively correlated with the number of forbidden patterns and negatively correlated with the permutation entropy. Our empirical results suggest that these two physical tools are useful to discriminate the stage of stock market development and can be easily implemented.

  10. Buying cannabis in 'coffee shops'.

    PubMed

    Monshouwer, Karin; Van Laar, Margriet; Vollebergh, Wilma A

    2011-03-01

    The key objective of Dutch cannabis policy is to prevent and limit the risks of cannabis consumption for users, their direct environment and society ('harm reduction'). This paper will focus on the tolerated sale of cannabis in 'coffee shops'. We give a brief overview of Dutch policy on coffee shops, its history and recent developments. Furthermore, we present epidemiological data that may be indicative of the effects of the coffee shop policy on cannabis and other drug use. Dutch coffee shop policy has become more restrictive in recent years and the number of coffee shops has decreased. Cannabis prevalence rates in the adult population are somewhat below the European average; the rate is relatively high among adolescents; and age of first use appears to be low. On a European level, the use of hard drugs in both the Dutch adult and adolescent population is average to low (except for ecstasy among adults). International comparisons do not suggest a strong, upward effect of the coffee shop system on levels of cannabis use, although prevalence rates among Dutch adolescents give rise to concern. Furthermore, the coffee shop system appears to be successful in separating the hard and soft drugs markets. Nevertheless, in recent years, issues concerning the involvement of organised crime and the public nuisance related to drug tourism have given rise to several restrictive measures on the local level and have sparked a political debate on the reform of Dutch drug policy. © 2011 Trimbos Institute.

  11. MITRE's virtual model shop

    NASA Astrophysics Data System (ADS)

    Wingfield, Michael A.

    1995-04-01

    The exploration of visual data and the use of visual information during the design process can be greatly enhanced by working within the virtual environment where the user is closely coupled to the data by means of immersive technologies and natural user interfaces. Current technology enables us to construct a virtual environment utilizing 3D graphics projection, object generated stereo sound, tactile feedback, and voice command input. Advances in software architectures and user interfaces enable us to focus on enhancing the design process within the virtual environment. These explorations at MITRE have evolved into an application which focuses on the ability to create, manipulate, and explore photo and audio realistic 3D models of work spaces, office complexes, and entire communities in real-time. This application, the Virtual Interactive Planning System, is a component of the MITRE virtual model shop, a suite of applications which permits the user to design and manipulate computer graphics models within the virtual environment.

  12. Technical and Occupational Shops. Volume II.

    ERIC Educational Resources Information Center

    Ontario Dept. of Education, Toronto. School Planning and Building Research Section.

    The layouts and specifications provided are intended as a guide to school boards, educators, and architects. Drawings and room plans illustrate specifications for girls' occupational shop, graphic arts, carpentry (millwork and building construction shop), boys' occupational shop (mechanical), boys' occupational shop (building construction),…

  13. A Permutation Test for Correlated Errors in Adjacent Questionnaire Items

    ERIC Educational Resources Information Center

    Hildreth, Laura A.; Genschel, Ulrike; Lorenz, Frederick O.; Lesser, Virginia M.

    2013-01-01

    Response patterns are of importance to survey researchers because of the insight they provide into the thought processes respondents use to answer survey questions. In this article we propose the use of structural equation modeling to examine response patterns and develop a permutation test to quantify the likelihood of observing a specific…

  14. Introduction to Permutation and Resampling-Based Hypothesis Tests

    ERIC Educational Resources Information Center

    LaFleur, Bonnie J.; Greevy, Robert A.

    2009-01-01

    A resampling-based method of inference--permutation tests--is often used when distributional assumptions are questionable or unmet. Not only are these methods useful for obvious departures from parametric assumptions (e.g., normality) and small sample sizes, but they are also more robust than their parametric counterparts in the presences of…

  15. Permutation/randomization-based inference for environmental data.

    PubMed

    Spicer, R Christopher; Gangloff, Harry J

    2016-03-01

    Quantitative inference from environmental contaminant data is almost exclusively from within the classic Neyman/Pearson (N/P) hypothesis-testing model, by which the mean serves as the fundamental quantitative measure, but which is constrained by random sampling and the assumption of normality in the data. Permutation/randomization-based inference originally forwarded by R. A. Fisher derives probability directly from the proportion of the occurrences of interest and is not dependent upon the distribution of data or random sampling. Foundationally, the underlying logic and the interpretation of the significance of the two models vary, but inference using either model can often be successfully applied. However, data examples from airborne environmental fungi (mold), asbestos in settled dust, and 1,2,3,4-tetrachlorobenzene (TeCB) in soil demonstrate potentially misleading inference using traditional N/P hypothesis testing based upon means/variance compared to permutation/randomization inference using differences in frequency of detection (Δf d). Bootstrapping and permutation testing, which are extensions of permutation/randomization, confirm calculated p values via Δf d and should be utilized to verify the appropriateness of a given data analysis by either model.

  16. Introduction to Permutation and Resampling-Based Hypothesis Tests

    ERIC Educational Resources Information Center

    LaFleur, Bonnie J.; Greevy, Robert A.

    2009-01-01

    A resampling-based method of inference--permutation tests--is often used when distributional assumptions are questionable or unmet. Not only are these methods useful for obvious departures from parametric assumptions (e.g., normality) and small sample sizes, but they are also more robust than their parametric counterparts in the presences of…

  17. Process Waste Assessment, Mechanics Shop

    SciTech Connect

    Phillips, N.M.

    1993-05-01

    This Process Waste Assessment was conducted to evaluate hazardous wastes generated in the Mechanics Shop. The Mechanics Shop maintains and repairs motorized vehicles and equipment on the SNL/California site, to include motorized carts, backhoes, street sweepers, trash truck, portable emergency generators, trencher, portable crane, and man lifts. The major hazardous waste streams routinely generated by the Mechanics Shop are used oil, spent off filters, oily rags, and spent batteries. The used off and spent off filters make up a significant portion of the overall hazardous waste stream. Waste oil and spent batteries are sent off-site for recycling. The rags and spent on filters are not recycled. They are disposed of as hazardous waste. Mechanics Shop personnel continuously look for opportunities to minimize hazardous wastes.

  18. Process Waste Assessment - Paint Shop

    SciTech Connect

    Phillips, N.M.

    1993-06-01

    This Process Waste Assessment was conducted to evaluate hazardous wastes generated in the Paint Shop, Building 913, Room 130. Special attention is given to waste streams generated by the spray painting process because it requires a number of steps for preparing, priming, and painting an object. Also, the spray paint booth covers the largest area in R-130. The largest and most costly waste stream to dispose of is {open_quote}Paint Shop waste{close_quotes} -- a combination of paint cans, rags, sticks, filters, and paper containers. These items are compacted in 55-gallon drums and disposed of as solid hazardous waste. Recommendations are made for minimizing waste in the Paint Shop. Paint Shop personnel are very aware of the need to minimize hazardous wastes and are continuously looking for opportunities to do so.

  19. [Materia medica in apothecary shops].

    PubMed

    Hadzović, S; Masić, I

    1999-01-01

    Even in 15th and 16th century there were people in Bosnia, preparing medicaments and selling different kinds of medical herbs. At first, they were Jews, later Muslims. They were called "attars"--drugsellers. They were very familiar with herbs of medical purpose. They could recognize herb by its colour and outlook. The goods were sold in specialized shops--attar shop. When analysing Materia Medica from an attar shop--according to the list from the 1911 (dr. Moritz Levy: "Sefards in Bosnia"), we can conclude that assortment of medical herbs and some medicaments was correct. Some Galen forms used in that time, are still in use nowadays. This paper describes all materials encompassed by Materia Medica. They are classified as organic and non-organic materials, and their use in therapy was also emphasized. Materia Medica of attar shops gives us a lot of material for research of non-official medicine and pharmacy from that time.

  20. Impeller Creation at the Fabrication Shop

    NASA Image and Video Library

    1950-10-21

    A mechanic and apprentice work on a wooden impeller in the Fabrication Shop at the NACA Lewis Flight Propulsion Laboratory. The 260-person Fabrication Division created almost all of the equipment and models used at the laboratory. The Technical Services Building, referred to as the “Fab Shop”, contained a number of specialized shops in the 1940s and 1950s. These included a Machine Shop, Sheet Metal Shop, Wood and Pattern Shop, Instrument Shop, Thermocouple Shop, Heat Treating Shop, Metallurgical Laboratory, and Fabrication Office. The Machine Shop fabricated research equipment not commercially available. During World War II these technicians produced high-speed cameras for combustion research, impellers and other supercharger components, and key equipment for the lab’s first supersonic wind tunnel. The Wood and Pattern Shop created everything from control panels and cabinets to aircraft model molds for sheet metal work. The Sheet Metal Shop had the ability to work with 0.01 to 4-inches thick steel plates. The Instrument Shop specialized in miniature parts and instrumentation, while the Thermocouple Shop standardized the installation of pitot tubes and thermocouples. The Metallurgical Laboratory contained a control lab for the Heat Treating Shop and a service lab for the NACA Lewis research divisions. The Heat Treating Shop heated metal parts to optimize their physical properties and contained a Precision Castings Foundry to manufacture equipment made of heat resisting alloys.

  1. RIGGERS LOFT/PAINT SHOP/SHEET METAL SHOP, VIEW TO SOUTHEAST. THE PAINT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    RIGGERS LOFT/PAINT SHOP/SHEET METAL SHOP, VIEW TO SOUTHEAST. THE PAINT SHOP WAS LOCATED IN THE CLOSEST CORNER OF THE BUILDING. THE SHEET METAL SHOP WAS LOCATED IN THE CORNER OF THE BUILDING ON THE RIGHT. THE RIGGERS LOFT WAS LOCATED IN THE PORTION OF THE BUILDING OUT OF VIEW TO THE LEFT - Rosie the Riveter National Historical Park, Riggers Loft/Paint Shop/Sheet Metal Shop, 1322 Canal Boulevard, Richmond, Contra Costa County, CA

  2. Fabrication Division Staff in the Machine Shop

    NASA Image and Video Library

    1946-07-21

    Machine Shop technicians in the Technical Service Building at the National Advisory Committee for Aeronautics (NACA) Lewis Flight Propulsion Laboratory. The 260-person Fabrication Division, led by Dan White and John Dalgleish, created almost all of the equipment and models used at the laboratory. The Technical Services Building, referred to as the Fab Shop, contained a number of specialized shops in the 1940s and 1950s. These included a Machine Shop, Sheet Metal Shop, Wood and Pattern Shop, Instrument Shop, Thermocouple Shop, Heat Treating Shop, Metallurgical Laboratory, and Fabrication Office. The Machine Shop fabricated specialized research equipment not commercially available. During World War II these technicians produced high-speed cameras for combustion research, impellers and other supercharger components, and key equipment for the lab’s first supersonic wind tunnel. The Wood and Pattern Shop created everything from control panels and cabinets to aircraft model molds for sheet metal work. The Sheet Metal Shop had the ability to work with 0.01 to 4-inch thick steel plates. The Instrument Shop specialized in miniature parts and instrumentation, while the Thermocouple Shop standardized the installation of pitot tubes and thermocouples.

  3. Quantitative in vivo solubility and reconstitution of truncated circular permutants of green fluorescent protein.

    PubMed

    Huang, Yao-Ming; Nayak, Sasmita; Bystroff, Christopher

    2011-11-01

    Several versions of split green fluorescent protein (GFP) fold and reconstitute fluorescence, as do many circular permutants, but little is known about the dependence of reconstitution on circular permutation. Explored here is the capacity of GFP to fold and reconstitute fluorescence from various truncated circular permutants, herein called "leave-one-outs" using a quantitative in vivo solubility assay and in vivo reconstitution of fluorescence. Twelve leave-one-out permutants are discussed, one for each of the 12 secondary structure elements. The results expand the outlook for the use of permuted split GFPs as specific and self-reporting gene encoded affinity reagents.

  4. Estimating Temporal Causal Interaction between Spike Trains with Permutation and Transfer Entropy

    PubMed Central

    Li, Zhaohui; Li, Xiaoli

    2013-01-01

    Estimating the causal interaction between neurons is very important for better understanding the functional connectivity in neuronal networks. We propose a method called normalized permutation transfer entropy (NPTE) to evaluate the temporal causal interaction between spike trains, which quantifies the fraction of ordinal information in a neuron that has presented in another one. The performance of this method is evaluated with the spike trains generated by an Izhikevich’s neuronal model. Results show that the NPTE method can effectively estimate the causal interaction between two neurons without influence of data length. Considering both the precision of time delay estimated and the robustness of information flow estimated against neuronal firing rate, the NPTE method is superior to other information theoretic method including normalized transfer entropy, symbolic transfer entropy and permutation conditional mutual information. To test the performance of NPTE on analyzing simulated biophysically realistic synapses, an Izhikevich’s cortical network that based on the neuronal model is employed. It is found that the NPTE method is able to characterize mutual interactions and identify spurious causality in a network of three neurons exactly. We conclude that the proposed method can obtain more reliable comparison of interactions between different pairs of neurons and is a promising tool to uncover more details on the neural coding. PMID:23940662

  5. Optimizing streamflow monitoring networks using joint permutation entropy

    NASA Astrophysics Data System (ADS)

    Stosic, Tatijana; Stosic, Borko; Singh, Vijay P.

    2017-09-01

    Using joint permutation entropy we address the issue of minimizing the cost of monitoring, while minimizing redundancy of the information content, of daily streamflow data recorded during the period 1989-2016 at twelve gauging stations on Brazos River, Texas, USA. While the conventional entropy measures take into account only the probability of occurrence of a given set of events, permutation entropy also takes into account local ordering of the sequential values, thus enriching the analysis. We find that the best cost efficiency is achieved by performing weekly measurements, in comparison with which daily measurements exhibit information redundancy, and monthly measurements imply information loss. We also find that the cumulative information redundancy of the twelve considered stations is over 10% for the observed period, and that the number of monitoring stations can be reduced by half bringing the cumulative redundancy level to less than 1%.

  6. The permuted locus trial--Well suited for emerging pathogens?

    PubMed

    Porco, Travis C; Keenan, Jeremy D; Enanoria, Wayne T A; Lietman, Thomas M

    2016-03-01

    The recent Ebola virus epidemic was waning by the time stakeholders were ready to field vaccines for testing but an evidence-based response to a novel pathogen will surely be required again. Here, we present a design for such a randomized controlled trial. The permuted locus trial was originally intended for studying the influence of water wells on trachoma. While outcomes can be measured in individuals, neither individuals nor groups are themselves randomized to arms, just potential well-sites, or in the case of an epidemic, index cases. The permuted locus trial may be used when classic individual and cluster-randomized trial design and analyses may not be optimal. Copyright © 2015 Elsevier Inc. All rights reserved.

  7. A Weak Quantum Blind Signature with Entanglement Permutation

    NASA Astrophysics Data System (ADS)

    Lou, Xiaoping; Chen, Zhigang; Guo, Ying

    2015-09-01

    Motivated by the permutation encryption algorithm, a weak quantum blind signature (QBS) scheme is proposed. It involves three participants, including the sender Alice, the signatory Bob and the trusted entity Charlie, in four phases, i.e., initializing phase, blinding phase, signing phase and verifying phase. In a small-scale quantum computation network, Alice blinds the message based on a quantum entanglement permutation encryption algorithm that embraces the chaotic position string. Bob signs the blinded message with private parameters shared beforehand while Charlie verifies the signature's validity and recovers the original message. Analysis shows that the proposed scheme achieves the secure blindness for the signer and traceability for the message owner with the aid of the authentic arbitrator who plays a crucial role when a dispute arises. In addition, the signature can neither be forged nor disavowed by the malicious attackers. It has a wide application to E-voting and E-payment system, etc.

  8. Holographic perfect shuffle permutation element for a miniaturized switching network

    NASA Astrophysics Data System (ADS)

    Kobolla, H.; Schmidt, J.; Gluch, E.; Schwider, J.

    1995-06-01

    A holographic perfect shuffle element with 80 channels for a miniaturized switching network is reported. An array of vertical-cavity, surface-emitting lasers is used as a transmitter. The whole permutation is carried out totally in glass. The 80 channels are permuted within a rectangle with a volume of 3 mm \\times 4 mm \\times 2 mm. Four planes of stacked volume holograms recorded in dichromated gelatin form this perfect shuffle element with an angular spectrum between 7 deg and 35 deg. Changes in the wavelength of the diode lasers to Delta lambda = +/-10 nm can be compensated with this setup. The overall efficiency per channel lies between 40% and 60%. When Fresnel reflections and absorption are taken into account, a transmission per hologram between 78% and 90% is achieved.

  9. Finite state model and compatibility theory - New analysis tools for permutation networks

    NASA Technical Reports Server (NTRS)

    Huang, S.-T.; Tripathi, S. K.

    1986-01-01

    A simple model to describe the fundamental operation theory of shuffle-exchange-type permutation networks, the finite permutation machine (FPM), is described, and theorems which transform the control matrix result to a continuous compatible vector result are developed. It is found that only 2n-1 shuffle exchange passes are necessary, and that 3n-3 passes are sufficient, to realize all permutations, reducing the sufficient number of passes by two from previous results. The flexibility of the approach is demonstrated by the description of a stack permutation machine (SPM) which can realize all permutations, and by showing that the FPM corresponding to the Benes (1965) network belongs to the SPM. The FPM corresponding to the network with two cascaded reverse-exchange networks is found to realize all permutations, and a simple mechanism to verify several equivalence relationships of various permutation networks is discussed.

  10. Encoding Sequential Information in Semantic Space Models: Comparing Holographic Reduced Representation and Random Permutation

    PubMed Central

    Recchia, Gabriel; Sahlgren, Magnus; Kanerva, Pentti; Jones, Michael N.

    2015-01-01

    Circular convolution and random permutation have each been proposed as neurally plausible binding operators capable of encoding sequential information in semantic memory. We perform several controlled comparisons of circular convolution and random permutation as means of encoding paired associates as well as encoding sequential information. Random permutations outperformed convolution with respect to the number of paired associates that can be reliably stored in a single memory trace. Performance was equal on semantic tasks when using a small corpus, but random permutations were ultimately capable of achieving superior performance due to their higher scalability to large corpora. Finally, “noisy” permutations in which units are mapped to other units arbitrarily (no one-to-one mapping) perform nearly as well as true permutations. These findings increase the neurological plausibility of random permutations and highlight their utility in vector space models of semantics. PMID:25954306

  11. Encoding sequential information in semantic space models: comparing holographic reduced representation and random permutation.

    PubMed

    Recchia, Gabriel; Sahlgren, Magnus; Kanerva, Pentti; Jones, Michael N

    2015-01-01

    Circular convolution and random permutation have each been proposed as neurally plausible binding operators capable of encoding sequential information in semantic memory. We perform several controlled comparisons of circular convolution and random permutation as means of encoding paired associates as well as encoding sequential information. Random permutations outperformed convolution with respect to the number of paired associates that can be reliably stored in a single memory trace. Performance was equal on semantic tasks when using a small corpus, but random permutations were ultimately capable of achieving superior performance due to their higher scalability to large corpora. Finally, "noisy" permutations in which units are mapped to other units arbitrarily (no one-to-one mapping) perform nearly as well as true permutations. These findings increase the neurological plausibility of random permutations and highlight their utility in vector space models of semantics.

  12. Successful attack on permutation-parity-machine-based neural cryptography.

    PubMed

    Seoane, Luís F; Ruttor, Andreas

    2012-02-01

    An algorithm is presented which implements a probabilistic attack on the key-exchange protocol based on permutation parity machines. Instead of imitating the synchronization of the communicating partners, the strategy consists of a Monte Carlo method to sample the space of possible weights during inner rounds and an analytic approach to convey the extracted information from one outer round to the next one. The results show that the protocol under attack fails to synchronize faster than an eavesdropper using this algorithm.

  13. Successful attack on permutation-parity-machine-based neural cryptography

    NASA Astrophysics Data System (ADS)

    Seoane, Luís F.; Ruttor, Andreas

    2012-02-01

    An algorithm is presented which implements a probabilistic attack on the key-exchange protocol based on permutation parity machines. Instead of imitating the synchronization of the communicating partners, the strategy consists of a Monte Carlo method to sample the space of possible weights during inner rounds and an analytic approach to convey the extracted information from one outer round to the next one. The results show that the protocol under attack fails to synchronize faster than an eavesdropper using this algorithm.

  14. The torus and the Klein bottle amplitude of permutation orbifolds

    NASA Astrophysics Data System (ADS)

    Kadar, Z.

    2000-07-01

    The torus and the Klein bottle amplitude coefficients are computed in permutation orbifolds of RCFT's in terms of the same quantities in the original theory and the twist group. An explicit expression is presented for the number of self conjugate primaries in the orbifold as a polynomial of the total number of primaries and the number of self conjugate ones in the parent theory. The formulae in the Z2 orbifold illustrate the general results.

  15. Testing of Error-Correcting Sparse Permutation Channel Codes

    NASA Technical Reports Server (NTRS)

    Shcheglov, Kirill, V.; Orlov, Sergei S.

    2008-01-01

    A computer program performs Monte Carlo direct numerical simulations for testing sparse permutation channel codes, which offer strong error-correction capabilities at high code rates and are considered especially suitable for storage of digital data in holographic and volume memories. A word in a code of this type is characterized by, among other things, a sparseness parameter (M) and a fixed number (K) of 1 or "on" bits in a channel block length of N.

  16. Gapped permutation pattern discovery for gene order comparisons.

    PubMed

    Parida, Laxmi

    2007-01-01

    The list of species whose complete DNA sequence have been read is growing steadily, and it is believed that comparative genomics is in its early days. Permutations patterns (groups of genes in some "close" proximity) on gene sequences of genomes across species is being studied under different models, to cope with this explosion of data. The challenge is to (intelligently and efficiently) analyze the genomes in the context of other genomes. In this paper, we present a generalized model that uses three notions, gapped permutation patterns (with gap g), genome clusters, via quorum, K>1, parameter, and, possible multiplicity in the patterns. The task is to automatically discover all permutation patterns (with possible multiplicity), that occur with gap g in at least K of the given m genomes. We present (log mN (I) + /Sigma/log/Sigma/N (O)) time algorithm where m is the number of sequences, each defined on Sigma, N (I) is the size of the input and N (O) is the size of the maximal gene clusters that appear in at least K of the m genomes.

  17. Retailing and Shopping on the Internet.

    ERIC Educational Resources Information Center

    Rowley, Jennifer

    1996-01-01

    Internet advertising and commercial activity are increasing. This article examines challenges facing the retail industry on the Internet: location; comparison shopping; security, especially financial transactions; customer base and profile; nature of the shopping experience; and legal and marketplace controls. (PEN)

  18. Retailing and Shopping on the Internet.

    ERIC Educational Resources Information Center

    Rowley, Jennifer

    1996-01-01

    Internet advertising and commercial activity are increasing. This article examines challenges facing the retail industry on the Internet: location; comparison shopping; security, especially financial transactions; customer base and profile; nature of the shopping experience; and legal and marketplace controls. (PEN)

  19. Shopping-Center in deutschen Mittelstädten und ihr Einfluss auf die Zentralitätsentwicklung. Eine Untersuchung unter der Verwendung von Einzelhandelskennzahlen

    NASA Astrophysics Data System (ADS)

    Eckhardt, Yannick

    2017-06-01

    Shopping-centers have been subject to intense analysis from various angles. Due to by the growing number of shopping-centers located in medium-sized cities, a change of money flows within the municipal boundaries is expected. On a multi-level basis this article shows key retail figures of medium-sized cities with shopping-centers in comparison to ones without. The final result reveals that the retail turnover of medium-sized cities with a shopping-center reaches a significantly higher level than cities without a shopping-center. Furthermore, the evaluation of data shows a rise of the retail centrality in medium sized towns as a consequence of the opening of a shopping-center. This means the construction of shopping-centers doesn't only cause a shift of money flows within the city boundaries but also leads to an additional influx of money from outside the municipalities.

  20. 13. Interior detail, Blacksmith Shop, showing a portion of the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. Interior detail, Blacksmith Shop, showing a portion of the original overhead belt drive system that powered machine tools in the adjacent Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific Railroad Carlin Shops, view to west, 135mm lens. - Southern Pacific Railroad, Carlin Shops, Roundhouse Machine Shop Extension, Foot of Sixth Street, Carlin, Elko County, NV

  1. Industrialization spawns the Elder Craftsmen Shop.

    PubMed

    Schreter, C A

    1984-01-01

    Research on the Wilmington Senior Center Elder Craftsmen Shop provides the background for this sociological examination of the role of the elder craftsmen shop in our society. The shop is put into historical context by discussing the development of pension plans and the evolution in the means of producing goods. It is argued that, as a social utility, the nonprofit elder craftsmen shop provides a uniquely flexible work situation. It allows for the expression of the work ethic in the framework of retirement.

  2. Finite state model and compatibility theory: New analysis tools for permutation networks

    SciTech Connect

    Huang, S.T.; Fripathi, S.K.

    1986-07-01

    In this paper, the authors present a new model, finite permutation machine (FPM), to describe the permutation networks. A set of theorems are developed to capture the theory of operations for the permutation networks. Using this new framework, an interesting problem is attacked: are 2n-1 passes of shuffle exchange necessary and sufficient to realize all permutations. where n=log/sub 2/N and N is the number of inputs and outputs interconnected by the network. They prove that to realize all permutations, 2n-1 passes of shuffle exchange are necessary and that 3n-3 passes are sufficient. This reduces the sufficient number of passes by 2 from the best-known result. Benes network is the most well-known network that can realize all permutations. To show the flexibility of the approach, the authors describe a general class of FPM, stack permutation machine (SPM), which can realize all permutations, and show that FPM corresponding to Benes network belongs to SPM. They also show that FPM corresponding to the network with 2 cascaded reverse-exchange networks can realize all permutations. To show the simplicity of the approach, they also present a very simple mechanism to verify several equivalence relationships of various permutation networks.

  3. 30 CFR 75.343 - Underground shops.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Underground shops. 75.343 Section 75.343... MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Ventilation § 75.343 Underground shops. (a) Underground shops shall be equipped with an automatic fire suppression system meeting the requirements of §...

  4. Metric Conversion and the School Shop

    ERIC Educational Resources Information Center

    Jackman, Arthur A.

    1976-01-01

    Cost of metric conversion in school shops is examined, and the author categories all the shops in the school and gives useful information on which shops are the easiest to convert, which are most complicated, where resistance is most likely to be met, and where conversion is most urgent. The math department is seen as catalyst. (Editor/HD)

  5. Handbook for Trade and Industrial Shop Teachers.

    ERIC Educational Resources Information Center

    Texas A and M Univ., College Station. Vocational Instructional Services.

    This handbook is intended to help teachers of pre-employment shop courses in organizing and delivering instruction in both the shop and classroom. Addressed in the guide are the following topics: the instructor's place in the local school organization; the instructor's job (objectives, advisory committees, occupational analysis, shop/classroom and…

  6. 30 CFR 57.4532 - Blacksmith shops.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Blacksmith shops. 57.4532 Section 57.4532 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... Control Installation/construction/maintenance § 57.4532 Blacksmith shops. Blacksmith shops located on...

  7. 30 CFR 57.4532 - Blacksmith shops.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Blacksmith shops. 57.4532 Section 57.4532 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... Control Installation/construction/maintenance § 57.4532 Blacksmith shops. Blacksmith shops located on...

  8. 30 CFR 57.4532 - Blacksmith shops.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Blacksmith shops. 57.4532 Section 57.4532 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... Control Installation/construction/maintenance § 57.4532 Blacksmith shops. Blacksmith shops located on...

  9. 30 CFR 57.4532 - Blacksmith shops.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Blacksmith shops. 57.4532 Section 57.4532 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... Control Installation/construction/maintenance § 57.4532 Blacksmith shops. Blacksmith shops located on...

  10. 30 CFR 57.4532 - Blacksmith shops.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Blacksmith shops. 57.4532 Section 57.4532 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... Control Installation/construction/maintenance § 57.4532 Blacksmith shops. Blacksmith shops located on...

  11. Innovativeness and Variety of Internet Shopping.

    ERIC Educational Resources Information Center

    Blake, Brian F.; Neuendorf, Kimberly A.; Valdiserri, Colin M.

    2003-01-01

    This survey of 208 Internet users examined the factors underlying Internet usage and shopping. Data were gathered on Information shopping (IS) innovativeness, overall IS frequency, visit variety, purchase variety, network prevalence, education, age, gender, employment, extensiveness of Internet use, and non-shopping Internet applications. (MES)

  12. 77 FR 56552 - Holiday Mobile Shopping Promotion

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-13

    ...] [Pages 56552-56554] [FR Doc No: 2012-22507] POSTAL SERVICE 39 CFR Part 111 Holiday Mobile Shopping... Holiday Mobile Shopping Promotion (``Promotion''), which will take place between November 7, 2012 and.../ Cyber Monday holiday shopping timeframe. In this final rule, the Postal Service provides a description...

  13. The Shopping Mall: A Teenager Hangout.

    ERIC Educational Resources Information Center

    Anthony, Kathryn H.

    1985-01-01

    Investigated teenagers' use of the shopping mall as a "hangout" through interviews with 51 adolescents using the mall, and 10 hours of behavioral observations. Results indicated that many teenagers visit the shopping center regularly to watch members of the opposite sex, play video games, see friends, shop, and people-watch. (Author/NRB)

  14. The Shopping Mall: A Teenager Hangout.

    ERIC Educational Resources Information Center

    Anthony, Kathryn H.

    1985-01-01

    Investigated teenagers' use of the shopping mall as a "hangout" through interviews with 51 adolescents using the mall, and 10 hours of behavioral observations. Results indicated that many teenagers visit the shopping center regularly to watch members of the opposite sex, play video games, see friends, shop, and people-watch. (Author/NRB)

  15. Innovativeness and Variety of Internet Shopping.

    ERIC Educational Resources Information Center

    Blake, Brian F.; Neuendorf, Kimberly A.; Valdiserri, Colin M.

    2003-01-01

    This survey of 208 Internet users examined the factors underlying Internet usage and shopping. Data were gathered on Information shopping (IS) innovativeness, overall IS frequency, visit variety, purchase variety, network prevalence, education, age, gender, employment, extensiveness of Internet use, and non-shopping Internet applications. (MES)

  16. Machine Shop Fundamentals: Part I.

    ERIC Educational Resources Information Center

    Kelly, Michael G.; And Others

    These instructional materials were developed and designed for secondary and adult limited English proficient students enrolled in machine tool technology courses. Part 1 includes 24 lessons covering introduction, safety and shop rules, basic machine tools, basic machine operations, measurement, basic blueprint reading, layout, and bench tools.…

  17. Machine Shop. Student Learning Guide.

    ERIC Educational Resources Information Center

    Palm Beach County Board of Public Instruction, West Palm Beach, FL.

    This student learning guide contains eight modules for completing a course in machine shop. It is designed especially for use in Palm Beach County, Florida. Each module covers one task, and consists of a purpose, performance objective, enabling objectives, learning activities and resources, information sheets, student self-check with answer key,…

  18. Machine Shop. Student Learning Guide.

    ERIC Educational Resources Information Center

    Palm Beach County Board of Public Instruction, West Palm Beach, FL.

    This student learning guide contains eight modules for completing a course in machine shop. It is designed especially for use in Palm Beach County, Florida. Each module covers one task, and consists of a purpose, performance objective, enabling objectives, learning activities and resources, information sheets, student self-check with answer key,…

  19. Drilling Machines: Vocational Machine Shop.

    ERIC Educational Resources Information Center

    Thomas, John C.

    The lessons and supportive information in this field tested instructional block provide a guide for teachers in developing a machine shop course of study in drilling. The document is comprised of operation sheets, information sheets, and transparency masters for 23 lessons. Each lesson plan includes a performance objective, material and tools,…

  20. Planning for Shops and Laboratories.

    ERIC Educational Resources Information Center

    North Carolina State Dept. of Public Instruction, Raleigh. Div. of School Planning.

    General guidelines for educators and architects in planning for industrial education, shops, and laboratory facilities necessary to the instructional program, are provided. Characteristics of the environment discussed are as follows--(1) spatial, (2) thermal, (3) visual, (4) sonic, and (5) aesthetic. Utility services covered are electrical power,…

  1. Sorting permutations by cut-circularize-linearize-and-paste operations.

    PubMed

    Huang, Keng-Hsuan; Chen, Kun-Tze; Lu, Chin Lung

    2011-11-30

    Genome rearrangements are studied on the basis of genome-wide analysis of gene orders and important in the evolution of species. In the last two decades, a variety of rearrangement operations, such as reversals, transpositions, block-interchanges, translocations, fusions and fissions, have been proposed to evaluate the differences between gene orders in two or more genomes. Usually, the computational studies of genome rearrangements are formulated as problems of sorting permutations by rearrangement operations. In this article, we study a sorting problem by cut-circularize-linearize-and-paste (CCLP) operations, which aims to find a minimum number of CCLP operations to sort a signed permutation representing a chromosome. The CCLP is a genome rearrangement operation that cuts a segment out of a chromosome, circularizes the segment into a temporary circle, linearizes the temporary circle as a linear segment, and possibly inverts the linearized segment and pastes it into the remaining chromosome. The CCLP operation can model many well-known rearrangements, such as reversals, transpositions and block-interchanges, and others not reported in the biological literature. In addition, it really occurs in the immune response of higher animals. To distinguish those CCLP operations from the reversal, we call them as non-reversal CCLP operations. In this study, we use permutation groups in algebra to design an O(δn) time algorithm for solving the weighted sorting problem by CCLP operations when the weight ratio between reversals and non-reversal CCLP operations is 1:2, where n is the number of genes in the given chromosome and δ is the number of needed CCLP operations. The algorithm we propose in this study is very simple so that it can be easily implemented with 1-dimensional arrays and useful in the studies of phylogenetic tree reconstruction and human immune response to tumors.

  2. Permutation test for periodicity in short time series data

    PubMed Central

    Ptitsyn, Andrey A; Zvonic, Sanjin; Gimble, Jeffrey M

    2006-01-01

    Background Periodic processes, such as the circadian rhythm, are important factors modulating and coordinating transcription of genes governing key metabolic pathways. Theoretically, even small fluctuations in the orchestration of circadian gene expression patterns among different tissues may result in functional asynchrony at the organism level and may contribute to a wide range of pathologic disorders. Identification of circadian expression pattern in time series data is important, but equally challenging. Microarray technology allows estimation of relative expression of thousands of genes at each time point. However, this estimation often lacks precision and microarray experiments are prohibitively expensive, limiting the number of data points in a time series expression profile. The data produced in these experiments carries a high degree of stochastic variation, obscuring the periodic pattern and a limited number of replicates, typically covering not more than two complete periods of oscillation. Results To address this issue, we have developed a simple, but effective, computational technique for the identification of a periodic pattern in relatively short time series, typical for microarray studies of circadian expression. This test is based on a random permutation of time points in order to estimate non-randomness of a periodogram. The Permutated time, or Pt-test, is able to detect oscillations within a given period in expression profiles dominated by a high degree of stochastic fluctuations or oscillations of different irrelevant frequencies. We have conducted a comprehensive study of circadian expression on a large data set produced at PBRC, representing three different peripheral murine tissues. We have also re-analyzed a number of similar time series data sets produced and published independently by other research groups over the past few years. Conclusion The Permutated time test (Pt-test) is demonstrated to be effective for detection of periodicity in

  3. Quantile-based permutation thresholds for quantitative trait loci hotspots.

    PubMed

    Neto, Elias Chaibub; Keller, Mark P; Broman, Andrew F; Attie, Alan D; Jansen, Ritsert C; Broman, Karl W; Yandell, Brian S

    2012-08-01

    Quantitative trait loci (QTL) hotspots (genomic locations affecting many traits) are a common feature in genetical genomics studies and are biologically interesting since they may harbor critical regulators. Therefore, statistical procedures to assess the significance of hotspots are of key importance. One approach, randomly allocating observed QTL across the genomic locations separately by trait, implicitly assumes all traits are uncorrelated. Recently, an empirical test for QTL hotspots was proposed on the basis of the number of traits that exceed a predetermined LOD value, such as the standard permutation LOD threshold. The permutation null distribution of the maximum number of traits across all genomic locations preserves the correlation structure among the phenotypes, avoiding the detection of spurious hotspots due to nongenetic correlation induced by uncontrolled environmental factors and unmeasured variables. However, by considering only the number of traits above a threshold, without accounting for the magnitude of the LOD scores, relevant information is lost. In particular, biologically interesting hotspots composed of a moderate to small number of traits with strong LOD scores may be neglected as nonsignificant. In this article we propose a quantile-based permutation approach that simultaneously accounts for the number and the LOD scores of traits within the hotspots. By considering a sliding scale of mapping thresholds, our method can assess the statistical significance of both small and large hotspots. Although the proposed approach can be applied to any type of heritable high-volume "omic" data set, we restrict our attention to expression (e)QTL analysis. We assess and compare the performances of these three methods in simulations and we illustrate how our approach can effectively assess the significance of moderate and small hotspots with strong LOD scores in a yeast expression data set.

  4. Quantile-Based Permutation Thresholds for Quantitative Trait Loci Hotspots

    PubMed Central

    Neto, Elias Chaibub; Keller, Mark P.; Broman, Andrew F.; Attie, Alan D.; Jansen, Ritsert C.; Broman, Karl W.; Yandell, Brian S.

    2012-01-01

    Quantitative trait loci (QTL) hotspots (genomic locations affecting many traits) are a common feature in genetical genomics studies and are biologically interesting since they may harbor critical regulators. Therefore, statistical procedures to assess the significance of hotspots are of key importance. One approach, randomly allocating observed QTL across the genomic locations separately by trait, implicitly assumes all traits are uncorrelated. Recently, an empirical test for QTL hotspots was proposed on the basis of the number of traits that exceed a predetermined LOD value, such as the standard permutation LOD threshold. The permutation null distribution of the maximum number of traits across all genomic locations preserves the correlation structure among the phenotypes, avoiding the detection of spurious hotspots due to nongenetic correlation induced by uncontrolled environmental factors and unmeasured variables. However, by considering only the number of traits above a threshold, without accounting for the magnitude of the LOD scores, relevant information is lost. In particular, biologically interesting hotspots composed of a moderate to small number of traits with strong LOD scores may be neglected as nonsignificant. In this article we propose a quantile-based permutation approach that simultaneously accounts for the number and the LOD scores of traits within the hotspots. By considering a sliding scale of mapping thresholds, our method can assess the statistical significance of both small and large hotspots. Although the proposed approach can be applied to any type of heritable high-volume “omic” data set, we restrict our attention to expression (e)QTL analysis. We assess and compare the performances of these three methods in simulations and we illustrate how our approach can effectively assess the significance of moderate and small hotspots with strong LOD scores in a yeast expression data set. PMID:22661325

  5. Security of the Five-Round KASUMI Type Permutation

    NASA Astrophysics Data System (ADS)

    Iwata, Tetsu; Yagi, Tohru; Kurosawa, Kaoru

    KASUMI is a blockcipher that forms the heart of the 3GPP confidentiality and integrity algorithms. In this paper, we study the security of the five-round KASUMI type permutations, and derive a highly non-trivial security bound against adversaries with adaptive chosen plaintext and chosen ciphertext attacks. To derive our security bound, we heavily use the tools from graph theory. However the result does not show its super-pseudorandomness, this gives us a strong evidence that the design of KASUMI is sound.

  6. Entanglement and symmetry in permutation-symmetric states

    SciTech Connect

    Markham, Damian J. H.

    2011-04-15

    We investigate the relationship between multipartite entanglement and symmetry, focusing on permutation symmetric states. We give a highly intuitive geometric interpretation to entanglement via the Majorana representation, where these states correspond to points on a unit sphere. We use this to show how various entanglement properties are determined by the symmetry properties of the states. The geometric measure of entanglement is thus phrased entirely as a geometric optimization and a condition for the equivalence of entanglement measures written in terms of point symmetries. Finally, we see that different symmetries of the states correspond to different types of entanglement with respect to interconvertibility under stochastic local operations and classical communication.

  7. Genuine multipartite nonlocality of permutationally invariant Gaussian states

    NASA Astrophysics Data System (ADS)

    Xu, Buqing; Tufarelli, Tommaso; Adesso, Gerardo

    2017-01-01

    We investigate genuine multipartite nonlocality of pure permutationally invariant multimode Gaussian states of continuous variable systems, as detected by the violation of Svetlichny inequality. We identify the phase space settings leading to the largest violation of the inequality when using displaced parity measurements, distinguishing our results between the cases of even and odd total number of modes. We further consider pseudospin measurements and show that, for three-mode states with asymptotically large squeezing degree, particular settings of these measurements allow one to approach the maximum violation of Svetlichny inequality allowed by quantum mechanics. This indicates that the strongest manifestation of genuine multipartite quantum nonlocality is in principle verifiable on Gaussian states.

  8. Photographs and Committees: Activities That Help Students Discover Permutations and Combinations.

    ERIC Educational Resources Information Center

    Szydlik, Jennifer Earles

    2000-01-01

    Presents problem situations that support students when discovering the multiplication principle, permutations, combinations, Pascal's triangle, and relationships among those objects in a concrete context. (ASK)

  9. Photographs and Committees: Activities That Help Students Discover Permutations and Combinations.

    ERIC Educational Resources Information Center

    Szydlik, Jennifer Earles

    2000-01-01

    Presents problem situations that support students when discovering the multiplication principle, permutations, combinations, Pascal's triangle, and relationships among those objects in a concrete context. (ASK)

  10. Construction of a random circular permutation library using an engineered transposon.

    PubMed

    Pierre, Brennal; Shah, Vandan; Xiao, Jenny; Kim, Jin Ryoun

    2015-04-01

    Circular permutation is an important protein engineering tool used to create sequence diversity of a protein by changing its linear order of amino acid sequence. Circular permutation has proven to be effective in the evolution of proteins for desired properties while maintaining similar three-dimensional structures. Due to the lack of a robust design principle guiding the selection of new termini, construction of a combinatorial library is much preferred for comprehensive evaluation of circular permutation. Unfortunately, the conventional methods used to create random circular permutation libraries cause significant sequence modification at new termini of circular permutants. In addition, these methods impose additional limitations by requiring either relatively inefficient blunt-end ligation during library construction or redesign of transposons for tailored expression of circular permutants. In this study, we present the development of an engineered transposon for facile construction of random circular permutation libraries. We provide evidence that minimal modification at the new termini of the random circular permutants is possible with our engineered transposon. In addition, our method enables the use of sticky-end ligation during library construction and provides external tunability for expression of random circular permutants.

  11. The complexity of gene expression dynamics revealed by permutation entropy

    PubMed Central

    2010-01-01

    Background High complexity is considered a hallmark of living systems. Here we investigate the complexity of temporal gene expression patterns using the concept of Permutation Entropy (PE) first introduced in dynamical systems theory. The analysis of gene expression data has so far focused primarily on the identification of differentially expressed genes, or on the elucidation of pathway and regulatory relationships. We aim to study gene expression time series data from the viewpoint of complexity. Results Applying the PE complexity metric to abiotic stress response time series data in Arabidopsis thaliana, genes involved in stress response and signaling were found to be associated with the highest complexity not only under stress, but surprisingly, also under reference, non-stress conditions. Genes with house-keeping functions exhibited lower PE complexity. Compared to reference conditions, the PE of temporal gene expression patterns generally increased upon stress exposure. High-complexity genes were found to have longer upstream intergenic regions and more cis-regulatory motifs in their promoter regions indicative of a more complex regulatory apparatus needed to orchestrate their expression, and to be associated with higher correlation network connectivity degree. Arabidopsis genes also present in other plant species were observed to exhibit decreased PE complexity compared to Arabidopsis specific genes. Conclusions We show that Permutation Entropy is a simple yet robust and powerful approach to identify temporal gene expression profiles of varying complexity that is equally applicable to other types of molecular profile data. PMID:21176199

  12. Permuting sparse rectangular matrices into block-diagonal form

    SciTech Connect

    Aykanat, Cevdet; Pinar, Ali; Catalyurek, Umit V.

    2002-12-09

    This work investigates the problem of permuting a sparse rectangular matrix into block diagonal form. Block diagonal form of a matrix grants an inherent parallelism for the solution of the deriving problem, as recently investigated in the context of mathematical programming, LU factorization and QR factorization. We propose graph and hypergraph models to represent the nonzero structure of a matrix, which reduce the permutation problem to those of graph partitioning by vertex separator and hypergraph partitioning, respectively. Besides proposing the models to represent sparse matrices and investigating related combinatorial problems, we provide a detailed survey of relevant literature to bridge the gap between different societies, investigate existing techniques for partitioning and propose new ones, and finally present a thorough empirical study of these techniques. Our experiments on a wide range of matrices, using state-of-the-art graph and hypergraph partitioning tools MeTiS and PaT oH, revealed that the proposed methods yield very effective solutions both in terms of solution quality and run time.

  13. Permutation auto-mutual information of electroencephalogram in anesthesia

    NASA Astrophysics Data System (ADS)

    Liang, Zhenhu; Wang, Yinghua; Ouyang, Gaoxiang; Voss, Logan J.; Sleigh, Jamie W.; Li, Xiaoli

    2013-04-01

    Objective. The dynamic change of brain activity in anesthesia is an interesting topic for clinical doctors and drug designers. To explore the dynamical features of brain activity in anesthesia, a permutation auto-mutual information (PAMI) method is proposed to measure the information coupling of electroencephalogram (EEG) time series obtained in anesthesia. Approach. The PAMI is developed and applied on EEG data collected from 19 patients under sevoflurane anesthesia. The results are compared with the traditional auto-mutual information (AMI), SynchFastSlow (SFS, derived from the BIS index), permutation entropy (PE), composite PE (CPE), response entropy (RE) and state entropy (SE). Performance of all indices is assessed by pharmacokinetic/pharmacodynamic (PK/PD) modeling and prediction probability. Main results. The PK/PD modeling and prediction probability analysis show that the PAMI index correlates closely with the anesthetic effect. The coefficient of determination R2 between PAMI values and the sevoflurane effect site concentrations, and the prediction probability Pk are higher in comparison with other indices. The information coupling in EEG series can be applied to indicate the effect of the anesthetic drug sevoflurane on the brain activity as well as other indices. The PAMI of the EEG signals is suggested as a new index to track drug concentration change. Significance. The PAMI is a useful index for analyzing the EEG dynamics during general anesthesia.

  14. Space Time Clustering and the Permutation Moments of Quadratic Form.

    PubMed

    Zhou, Yi-Hui; Mayhew, Gregory; Sun, Zhibin; Xu, Xiaolin; Zou, Fei; Wright, Fred A

    2013-01-01

    The Mantel and Knox space-time clustering statistics are popular tools to establish transmissibility of a disease and detect outbreaks. The most commonly used null distributional approximations may provide poor fits, and researchers often resort to direct sampling from the permutation distribution. However, the exact first four moments for these statistics are available, and Pearson distributional approximations are often effective. Thus, our first goal is to clarify the literature and to make these tools more widely available. In addition, by rewriting terms in the statistics we obtain the exact first four permutation moments for the most commonly used quadratic form statistics, which need not be positive definite. The extension of this work to quadratic forms greatly expands the utility of density approximations for these problems, including for high-dimensional applications, where the statistics must be extreme in order to exceed stringent testing thresholds. We demonstrate the methods using examples from the investigation of disease transmission in cattle, the association of a gene expression pathway with breast cancer survival, regional genetic association with cystic fibrosis lung disease, and hypothesis testing for smoothed local linear regression.

  15. Genetic algorithms with permutation coding for multiple sequence alignment.

    PubMed

    Ben Othman, Mohamed Tahar; Abdel-Azim, Gamil

    2013-08-01

    Multiple sequence alignment (MSA) is one of the topics of bio informatics that has seriously been researched. It is known as NP-complete problem. It is also considered as one of the most important and daunting tasks in computational biology. Concerning this a wide number of heuristic algorithms have been proposed to find optimal alignment. Among these heuristic algorithms are genetic algorithms (GA). The GA has mainly two major weaknesses: it is time consuming and can cause local minima. One of the significant aspects in the GA process in MSA is to maximize the similarities between sequences by adding and shuffling the gaps of Solution Coding (SC). Several ways for SC have been introduced. One of them is the Permutation Coding (PC). We propose a hybrid algorithm based on genetic algorithms (GAs) with a PC and 2-opt algorithm. The PC helps to code the MSA solution which maximizes the gain of resources, reliability and diversity of GA. The use of the PC opens the area by applying all functions over permutations for MSA. Thus, we suggest an algorithm to calculate the scoring function for multiple alignments based on PC, which is used as fitness function. The time complexity of the GA is reduced by using this algorithm. Our GA is implemented with different selections strategies and different crossovers. The probability of crossover and mutation is set as one strategy. Relevant patents have been probed in the topic.

  16. Exploiting Lipid Permutation Symmetry to Compute Membrane Remodeling Free Energies

    NASA Astrophysics Data System (ADS)

    Bubnis, Greg; Risselada, Herre Jelger; Grubmüller, Helmut

    2016-10-01

    A complete physical description of membrane remodeling processes, such as fusion or fission, requires knowledge of the underlying free energy landscapes, particularly in barrier regions involving collective shape changes, topological transitions, and high curvature, where Canham-Helfrich (CH) continuum descriptions may fail. To calculate these free energies using atomistic simulations, one must address not only the sampling problem due to high free energy barriers, but also an orthogonal sampling problem of combinatorial complexity stemming from the permutation symmetry of identical lipids. Here, we solve the combinatorial problem with a permutation reduction scheme to map a structural ensemble into a compact, nondegenerate subregion of configuration space, thereby permitting straightforward free energy calculations via umbrella sampling. We applied this approach, using a coarse-grained lipid model, to test the CH description of bending and found sharp increases in the bending modulus for curvature radii below 10 nm. These deviations suggest that an anharmonic bending term may be required for CH models to give quantitative energetics of highly curved states.

  17. Maze permutations during minimally invasive mitral valve surgery

    PubMed Central

    2015-01-01

    Surgical ablation for atrial fibrillation is most frequently done in the concomitant setting, and most commonly with mitral valve surgery. Minimally invasive surgical techniques for the treatment of atrial fibrillation have developed contemporaneously with techniques for minimally invasive mitral valve surgery. As in traditional surgery for atrial fibrillation, there are many different permutations of ablations for the less invasive approaches. Lesion sets can vary from simple pulmonary vein isolation (PVI) to full bi-atrial lesions that completely reproduce the traditional cut-and-sew Cox Maze III procedure with variable efficacy in restoring sinus rhythm. Additionally, treatment of the atrial appendage can be done through minimally invasive approaches without any ablation at all in an attempt to mitigate the risk of stroke. Finally, hybrid procedures combining minimally invasive surgery and catheter-based ablation are being developed that might augment surgical treatment of atrial fibrillation at the time of minimally invasive mitral valve repair. These various permutations and their results are reviewed. PMID:26539352

  18. Commodity predictability analysis with a permutation information theory approach

    NASA Astrophysics Data System (ADS)

    Zunino, Luciano; Tabak, Benjamin M.; Serinaldi, Francesco; Zanin, Massimiliano; Pérez, Darío G.; Rosso, Osvaldo A.

    2011-03-01

    It is widely known that commodity markets are not totally efficient. Long-range dependence is present, and thus the celebrated Brownian motion of prices can be considered only as a first approximation. In this work we analyzed the predictability in commodity markets by using a novel approach derived from Information Theory. The complexity-entropy causality plane has been recently shown to be a useful statistical tool to distinguish the stage of stock market development because differences between emergent and developed stock markets can be easily discriminated and visualized with this representation space [L. Zunino, M. Zanin, B.M. Tabak, D.G. Pérez, O.A. Rosso, Complexity-entropy causality plane: a useful approach to quantify the stock market inefficiency, Physica A 389 (2010) 1891-1901]. By estimating the permutation entropy and permutation statistical complexity of twenty basic commodity future markets over a period of around 20 years (1991.01.02-2009.09.01), we can define an associated ranking of efficiency. This ranking is quantifying the presence of patterns and hidden structures in these prime markets. Moreover, the temporal evolution of the commodities in the complexity-entropy causality plane allows us to identify periods of time where the underlying dynamics is more or less predictable.

  19. Shopping Problems among High School Students

    PubMed Central

    Grant, Jon E.; Potenza, Marc N.; Krishnan-Sarin, Suchitra; Cavallo, Dana A.; Desai, Rani A.

    2010-01-01

    Background Although shopping behavior among adolescents is normal, for some the shopping becomes problematic. An assessment of adolescent shopping behavior along a continuum of severity and its relationship to other behaviors and health issues is incompletely understood. Methods A large sample of high school students (n=3999) was examined using a self-report survey with 153 questions concerning demographic characteristics, shopping behaviors, other health behaviors including substance use, and functioning variables such as grades and violent behavior. Results The overall prevalence of problem shopping was 3.5% (95%CI: 2.93–4.07). Regular smoking, marijuana and other drug use, sadness and hopelessness, and antisocial behaviors (e.g., fighting, carrying weapons) were associated with problem shopping behavior in both boys and girls. Heavy alcohol use was significantly associated with problem shopping only in girls. Conclusion Problem shopping appears fairly common among high school students and is associated with symptoms of depression and a range of potentially addictive and antisocial behaviors. Significant distress and diminished behavioral control suggest that excessive shopping may often have significant associated morbidity. Additional research is needed to develop specific prevention and treatment strategies for adolescents who report problems with shopping. PMID:21497217

  20. Shopping problems among high school students.

    PubMed

    Grant, Jon E; Potenza, Marc N; Krishnan-Sarin, Suchitra; Cavallo, Dana A; Desai, Rani A

    2011-01-01

    Although shopping behavior among adolescents is normal, for some, the shopping becomes problematic. An assessment of adolescent shopping behavior along a continuum of severity and its relationship to other behaviors and health issues is incompletely understood. A large sample of high school students (n = 3999) was examined using a self-report survey with 153 questions concerning demographic characteristics, shopping behaviors, other health behaviors including substance use, and functioning variables such as grades and violent behavior. The overall prevalence of problem shopping was 3.5% (95% CI, 2.93-4.07). Regular smoking, marijuana and other drug use, sadness and hopelessness, and antisocial behaviors (e.g., fighting, carrying weapons) were associated with problem shopping behavior in both boys and girls. Heavy alcohol use was significantly associated with problem shopping only in girls. Problem shopping appears fairly common among high school students and is associated with symptoms of depression and a range of potentially addictive and antisocial behaviors. Significant distress and diminished behavioral control suggest that excessive shopping may often have significant associated morbidity. Additional research is needed to develop specific prevention and treatment strategies for adolescents who report problems with shopping. Copyright © 2011 Elsevier Inc. All rights reserved.

  1. 5. VIEW EASTOPENING IN WEST ELEVATION OF BLACKSMITH SHOP SECTION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. VIEW EAST-OPENING IN WEST ELEVATION OF BLACKSMITH SHOP SECTION OF THE BETHLEHEM STEEL COMPANY SHIPYARD BLACKSMITH SHOP/BOILER SHOP. - Bethlehem Steel Company Shipyard, Blacksmith Shop-Boiler Shop, 1201-1321 Hudson Street, Hoboken, Hudson County, NJ

  2. 18. Interior detail, drill press and grinder, Machine Shop, Roundhouse ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. Interior detail, drill press and grinder, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific Railroad Carlin Shops, view to east (135mm lens). - Southern Pacific Railroad, Carlin Shops, Roundhouse Machine Shop Extension, Foot of Sixth Street, Carlin, Elko County, NV

  3. 19. Interior detail, grinder and drill press, Machine Shop, Roundhouse ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. Interior detail, grinder and drill press, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific Railroad Carlin Shops, view to south (135mm lens). - Southern Pacific Railroad, Carlin Shops, Roundhouse Machine Shop Extension, Foot of Sixth Street, Carlin, Elko County, NV

  4. Four applications of permutation methods to testing a single-mediator model.

    PubMed

    Taylor, Aaron B; MacKinnon, David P

    2012-09-01

    Four applications of permutation tests to the single-mediator model are described and evaluated in this study. Permutation tests work by rearranging data in many possible ways in order to estimate the sampling distribution for the test statistic. The four applications to mediation evaluated here are the permutation test of ab, the permutation joint significance test, and the noniterative and iterative permutation confidence intervals for ab. A Monte Carlo simulation study was used to compare these four tests with the four best available tests for mediation found in previous research: the joint significance test, the distribution of the product test, and the percentile and bias-corrected bootstrap tests. We compared the different methods on Type I error, power, and confidence interval coverage. The noniterative permutation confidence interval for ab was the best performer among the new methods. It successfully controlled Type I error, had power nearly as good as the most powerful existing methods, and had better coverage than any existing method. The iterative permutation confidence interval for ab had lower power than do some existing methods, but it performed better than any other method in terms of coverage. The permutation confidence interval methods are recommended when estimating a confidence interval is a primary concern. SPSS and SAS macros that estimate these confidence intervals are provided.

  5. Using R to Simulate Permutation Distributions for Some Elementary Experimental Designs

    ERIC Educational Resources Information Center

    Eudey, T. Lynn; Kerr, Joshua D.; Trumbo, Bruce E.

    2010-01-01

    Null distributions of permutation tests for two-sample, paired, and block designs are simulated using the R statistical programming language. For each design and type of data, permutation tests are compared with standard normal-theory and nonparametric tests. These examples (often using real data) provide for classroom discussion use of metrics…

  6. Four applications of permutation methods to testing a single-mediator model

    PubMed Central

    MacKinnon, David P.

    2012-01-01

    Four applications of permutation tests to the single-mediator model are described and evaluated in this study. Permutation tests work by rearranging data in many possible ways in order to estimate the sampling distribution for the test statistic. The four applications to mediation evaluated here are the permutation test of ab, the permutation joint significance test, and the noniterative and iterative permutation confidence intervals for ab. A Monte Carlo simulation study was used to compare these four tests with the four best available tests for mediation found in previous research: the joint significance test, the distribution of the product test, and the percentile and bias-corrected bootstrap tests. We compared the different methods on Type I error, power, and confidence interval coverage. The noniterative permutation confidence interval for ab was the best performer among the new methods. It successfully controlled Type I error, had power nearly as good as the most powerful existing methods, and had better coverage than any existing method. The iterative permutation confidence interval for ab had lower power than do some existing methods, but it performed better than any other method in terms of coverage. The permutation confidence interval methods are recommended when estimating a confidence interval is a primary concern. SPSS and SAS macros that estimate these confidence intervals are provided. PMID:22311738

  7. Students' Errors in Solving the Permutation and Combination Problems Based on Problem Solving Steps of Polya

    ERIC Educational Resources Information Center

    Sukoriyanto; Nusantara, Toto; Subanji; Chandra, Tjang Daniel

    2016-01-01

    This article was written based on the results of a study evaluating students' errors in problem solving of permutation and combination in terms of problem solving steps according to Polya. Twenty-five students were asked to do four problems related to permutation and combination. The research results showed that the students still did a mistake in…

  8. Using R to Simulate Permutation Distributions for Some Elementary Experimental Designs

    ERIC Educational Resources Information Center

    Eudey, T. Lynn; Kerr, Joshua D.; Trumbo, Bruce E.

    2010-01-01

    Null distributions of permutation tests for two-sample, paired, and block designs are simulated using the R statistical programming language. For each design and type of data, permutation tests are compared with standard normal-theory and nonparametric tests. These examples (often using real data) provide for classroom discussion use of metrics…

  9. Statistical Significance of the Contribution of Variables to the PCA Solution: An Alternative Permutation Strategy

    ERIC Educational Resources Information Center

    Linting, Marielle; van Os, Bart Jan; Meulman, Jacqueline J.

    2011-01-01

    In this paper, the statistical significance of the contribution of variables to the principal components in principal components analysis (PCA) is assessed nonparametrically by the use of permutation tests. We compare a new strategy to a strategy used in previous research consisting of permuting the columns (variables) of a data matrix…

  10. Permutation-parity exchange at a beam splitter: Application to Heisenberg-limited interferometry

    SciTech Connect

    Campos, Richard A.; Gerry, Christopher C.

    2005-12-15

    Quantum-optical permutation and parity observables are unitarily exchanged by a 50:50 beam splitter. Bosonic coalescence effects are reexamined from this point of view. We show that photon-number resolving counters behind a beam splitter define a permutation detector for the input optical field. With suitable phase encoding, the detector also enables Heisenberg-limited interferometry.

  11. Passion and dependency in online shopping activities.

    PubMed

    Wang, Chih-Chien; Yang, Hui-Wen

    2007-04-01

    This study examines the influence of harmonious passion (HP) and obsessive passion (OP) to online shopping dependency. The results show that both HP and OP might lead to online shopping dependency and online shoppers with OP are more dependent on online shopping activities. In addition, this study also found out that HP and OP could be denoted as a sequence of different intensities of passion, where HP might be a necessity of OP.

  12. Permutation symmetry and the origin of fermion mass hierarchy

    SciTech Connect

    Babu, K.S.; Mohapatra, R.N. )

    1990-06-04

    A realization of the flavor-democracy'' approach to quark and lepton masses is provided in the context of the standard model with a horizontal {ital S}{sub 3} permutation symmetry. In this model, {ital t} and {ital b} quarks pick up mass at the tree level, {ital c}, {ital s}-quark and {tau}-lepton masses arise at the one-loop level, {ital u}, {ital d}, and {mu} masses at the two-loop level, and the electron mass at the three-loop level, thus reproducing the observed hierarchial structure without fine tuning of the Yukawa couplings. The pattern of quark mixing angles also emerges naturally, with {ital V}{sub {ital u}{ital s}},{ital V}{sub {ital c}{ital b}}{approx}{ital O}({epsilon}), {ital V}{sub {ital u}{ital b}}{approx}{ital O}({epsilon}{sup 2}), where {epsilon} is a loop expansion parameter.

  13. Refined scale-dependent permutation entropy to analyze systems complexity

    NASA Astrophysics Data System (ADS)

    Wu, Shuen-De; Wu, Chiu-Wen; Humeau-Heurtier, Anne

    2016-05-01

    Multiscale entropy (MSE) has become a prevailing method to quantify the complexity of systems. Unfortunately, MSE has a temporal complexity in O(N2) , which is unrealistic for long time series. Moreover, MSE relies on the sample entropy computation which is length-dependent and which leads to large variance and possible undefined entropy values for short time series. Here, we propose and introduce a new multiscale complexity measure, the refined scale-dependent permutation entropy (RSDPE). Through the processing of different kinds of synthetic data and real signals, we show that RSDPE has a behavior close to the one of MSE. Furthermore, RSDPE has a temporal complexity in O(N) . Finally, RSDPE has the advantage of being much less length-dependent than MSE. From all this, we conclude that RSDPE over-performs MSE in terms of computational cost and computational accuracy.

  14. T-duality as permutation of coordinates in double space

    NASA Astrophysics Data System (ADS)

    Sazdović, B.

    2017-05-01

    We introduce the 2D dimensional double space with the coordinates ZM = (xμ , yμ ), whose components are the coordinates of initial space xμ and its T-dual yμ . We shall show that in this extended space the T-duality transformations can be realized simply by exchanging the places of some coordinates xa , along which we want to perform T-duality, and the corresponding dual coordinates ya . In such an approach it is evident that T-duality leads to the physically equivalent theory and that a complete set of T-duality transformations forms a subgroup of the 2D permutation group. So, in double space we are able to represent the backgrounds of all T-dual theories in a unified manner. Supported by the Serbian Ministry of Education and Science (171031)

  15. Geological applications of multi-response permutation procedures

    USGS Publications Warehouse

    Orlowski, L.A.; Grundy, W.D.; Mielke, P.W.; Schumm, S.A.

    1993-01-01

    The multi-purpose permutation procedures (MRPP) test statistic is designed to analyze multivariate data at the ordinal or higher levels. It is based on the weighted averages of symmetric distance functions over all paired objects within a priori disjoint groups of objects from a finite population of objects where each object's response is a point in an r-dimensional space. Thus, the arguments of each r-dimensional point correspond to the r measured responses of each object in the finite population of objects. The null hypothesis underlying MRPP is that the observed sample of objects within groups of a specified size structure is randomly obtained from the pooled collection of objects comprising the finite population. The procedure is used to test the presumed geomorphic differences among three reaches of the Lower Mississippi River. A combination of the proposed reaches is favored and several variable-based reach configurations are proposed. ?? 1993 International Association for Mathernatical Geology.

  16. Permutation Entropy Applied to Movement Behaviors of Drosophila Melanogaster

    NASA Astrophysics Data System (ADS)

    Liu, Yuedan; Chon, Tae-Soo; Baek, Hunki; Do, Younghae; Choi, Jin Hee; Chung, Yun Doo

    Movement of different strains in Drosophila melanogaster was continuously observed by using computer interfacing techniques and was analyzed by permutation entropy (PE) after exposure to toxic chemicals, toluene (0.1 mg/m3) and formaldehyde (0.01 mg/m3). The PE values based on one-dimensional time series position (vertical) data were variable according to internal constraint (i.e. strains) and accordingly increased in response to external constraint (i.e. chemicals) by reflecting diversity in movement patterns from both normal and intoxicated states. Cross-correlation function revealed temporal associations between the PE values and between the component movement patterns in different chemicals and strains through the period of intoxication. The entropy based on the order of position data could be a useful means for complexity measure in behavioral changes and for monitoring the impact of stressors in environment.

  17. Discriminating chaotic and stochastic dynamics through the permutation spectrum test

    SciTech Connect

    Kulp, C. W.; Zunino, L.

    2014-09-01

    In this paper, we propose a new heuristic symbolic tool for unveiling chaotic and stochastic dynamics: the permutation spectrum test. Several numerical examples allow us to confirm the usefulness of the introduced methodology. Indeed, we show that it is robust in situations in which other techniques fail (intermittent chaos, hyperchaotic dynamics, stochastic linear and nonlinear correlated dynamics, and deterministic non-chaotic noise-driven dynamics). We illustrate the applicability and reliability of this pragmatic method by examining real complex time series from diverse scientific fields. Taking into account that the proposed test has the advantages of being conceptually simple and computationally fast, we think that it can be of practical utility as an alternative test for determinism.

  18. Circular Permutation of a Chaperonin Protein: Biophysics and Application to Nanotechnology

    NASA Technical Reports Server (NTRS)

    Paavola, Chad; Chan, Suzanne; Li, Yi-Fen; McMillan, R. Andrew; Trent, Jonathan

    2004-01-01

    We have designed five circular permutants of a chaperonin protein derived from the hyperthermophilic organism Sulfolobus shibatae. These permuted proteins were expressed in E. coli and are well-folded. Furthermore, all the permutants assemble into 18-mer double rings of the same form as the wild-type protein. We characterized the thermodynamics of folding for each permutant by both guanidine denaturation and differential scanning calorimetry. We also examined the assembly of chaperonin rings into higher order structures that may be used as nanoscale templates. The results show that circular permutation can be used to tune the thermodynamic properties of a protein template as well as facilitating the fusion of peptides, binding proteins or enzymes onto nanostructured templates.

  19. Circular Permutation of a Chaperonin Protein: Biophysics and Application to Nanotechnology

    NASA Technical Reports Server (NTRS)

    Paavola, Chad; Chan, Suzanne; Li, Yi-Fen; McMillan, R. Andrew; Trent, Jonathan

    2004-01-01

    We have designed five circular permutants of a chaperonin protein derived from the hyperthermophilic organism Sulfolobus shibatae. These permuted proteins were expressed in E. coli and are well-folded. Furthermore, all the permutants assemble into 18-mer double rings of the same form as the wild-type protein. We characterized the thermodynamics of folding for each permutant by both guanidine denaturation and differential scanning calorimetry. We also examined the assembly of chaperonin rings into higher order structures that may be used as nanoscale templates. The results show that circular permutation can be used to tune the thermodynamic properties of a protein template as well as facilitating the fusion of peptides, binding proteins or enzymes onto nanostructured templates.

  20. A self-adaptive image encryption scheme with half-pixel interchange permutation operation

    NASA Astrophysics Data System (ADS)

    Ye, Ruisong; Liu, Li; Liao, Minyu; Li, Yafang; Liao, Zikang

    2017-01-01

    A plain-image dependent image encryption scheme with half-pixel-level swapping permutation strategy is proposed. In the new permutation operation, a pixel-swapping operation between four higher bit-planes and four lower bit-planes is employed to replace the traditional confusion operation, which not only improves the conventional permutation efficiency within the plain-image, but also changes all the pixel gray values. The control parameters of generalized Arnold map applied for the permutation operation are related to the plain-image content and consequently can resist chosen-plaintext and known-plaintext attacks effectively. To enhance the security of the proposed image encryption, one multimodal skew tent map is applied to generate pseudo-random gray value sequence for diffusion operation. Simulations have been carried out thoroughly to demonstrate that the proposed image encryption scheme is highly secure thanks to its large key space and efficient permutation-diffusion operations.

  1. VIEW NORTHLEFTBUILDING 32MACHINE SHOP (1890) CENTERBUILDING BLACKSMITH SHOP (1885) RIGHTBUILDING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW NORTH-LEFT-BUILDING 32-MACHINE SHOP (1890) CENTER-BUILDING BLACKSMITH SHOP (1885) RIGHT-BUILDING 40-ROPE WAREHOUSE (1915) 3 STORIES BUILDING 42-ROPE SHOP (1910) - John A. Roebling's Sons Company & American Steel & Wire Company, South Broad, Clark, Elmer, Mott & Hudson Streets, Trenton, Mercer County, NJ

  2. ERECTING SHOP, EAST SIDE, LOOKING SOUTH. LEFT FOREGROUND BREAK IN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    ERECTING SHOP, EAST SIDE, LOOKING SOUTH. LEFT FOREGROUND BREAK IN WALL IS FOR PASSAGE OF STEAM-POWERED BELTING FROM POWERHOUSE. - Southern Pacific, Sacramento Shops, Erecting Shop, 111 I Street, Sacramento, Sacramento County, CA

  3. 7. NW corner of Blacksmith Shop showing roof truss connection ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. NW corner of Blacksmith Shop showing roof truss connection at top of brick wall. - Central of Georgia Railway, Savannah Repair Shops & Terminal Facilities, Blacksmith Shop, Bounded by West Broad, Jones, West Boundary & Hull Streets, Savannah, Chatham County, GA

  4. 5. Interior view looking W down length of Blacksmith Shop ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Interior view looking W down length of Blacksmith Shop - Central of Georgia Railway, Savannah Repair Shops & Terminal Facilities, Blacksmith Shop, Bounded by West Broad, Jones, West Boundary & Hull Streets, Savannah, Chatham County, GA

  5. 8. Exterior view of Blacksmith Shop window. Central of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Exterior view of Blacksmith Shop window. - Central of Georgia Railway, Savannah Repair Shops & Terminal Facilities, Blacksmith Shop, Bounded by West Broad, Jones, West Boundary & Hull Streets, Savannah, Chatham County, GA

  6. 2. Partial N elevation of Blacksmith Shop. Central of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Partial N elevation of Blacksmith Shop. - Central of Georgia Railway, Savannah Repair Shops & Terminal Facilities, Blacksmith Shop, Bounded by West Broad, Jones, West Boundary & Hull Streets, Savannah, Chatham County, GA

  7. 6. Interior of W end wall Blacksmith Shop. Central ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Interior of W end wall Blacksmith Shop. - Central of Georgia Railway, Savannah Repair Shops & Terminal Facilities, Blacksmith Shop, Bounded by West Broad, Jones, West Boundary & Hull Streets, Savannah, Chatham County, GA

  8. BLACKSMITH SHOP ROOF STRUCTURE AT JUNCTION BETWEEN 60 FT. AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    BLACKSMITH SHOP ROOF STRUCTURE AT JUNCTION BETWEEN 60 FT. AND 90 FT. SPAN ROOF TRUSSES, LOOKING SOUTH. - Southern Pacific, Sacramento Shops, Blacksmith Shop, 111 I Street, Sacramento, Sacramento County, CA

  9. 1. Threequarter view of W elevation of Blacksmith Shop. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Three-quarter view of W elevation of Blacksmith Shop. - Central of Georgia Railway, Savannah Repair Shops & Terminal Facilities, Blacksmith Shop, Bounded by West Broad, Jones, West Boundary & Hull Streets, Savannah, Chatham County, GA

  10. PAINT SHOP, DETAIL OF FABRICATED COLUMN AT JUNCTION OF WEST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PAINT SHOP, DETAIL OF FABRICATED COLUMN AT JUNCTION OF WEST BAY (ORIGINAL) AND CENTER BAYS (SECOND ADDITION), LOOKING NORTHEAST. - Southern Pacific, Sacramento Shops, Paint Shop, 111 I Street, Sacramento, Sacramento County, CA

  11. PAINT SHOP, FIRST FLOOR, NORTHEAST CORNER OFFICE INTERIOR, LOOKING WEST. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PAINT SHOP, FIRST FLOOR, NORTHEAST CORNER OFFICE INTERIOR, LOOKING WEST. PROJECTING WALLS WITH INFILLED ARCHES WERE PART OF ONE PAINTING BOOTH IN ORIGINAL STRUCTURE. - Southern Pacific, Sacramento Shops, Paint Shop, 111 I Street, Sacramento, Sacramento County, CA

  12. CAR SHOP TRANSFER TABLE, IN STORAGE AT WEST SIDE OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    CAR SHOP TRANSFER TABLE, IN STORAGE AT WEST SIDE OF SHOPS, THREE-QUARTER VIEW, LOOKING NORTHWEST. - Southern Pacific, Sacramento Shops, Pitless Transfer Table, 111 I Street, Sacramento, Sacramento County, CA

  13. CAR SHOP TRANSFER TABLE, IN STORAGE AT WEST SIDE OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    CAR SHOP TRANSFER TABLE, IN STORAGE AT WEST SIDE OF SHOPS, DRIVE GEAR AT EAST END (MOTOR REMOVED), LOOKING SOUTHEAST. - Southern Pacific, Sacramento Shops, Pitless Transfer Table, 111 I Street, Sacramento, Sacramento County, CA

  14. 9. LOOKING NORTH ON SPRUCE STREET, SHOWING MILLWRIGHT SHOP, FITTING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. LOOKING NORTH ON SPRUCE STREET, SHOWING MILLWRIGHT SHOP, FITTING SHOP, ADMINISTRATION BUILDING AND ERECTING SHOP - UNION WORKS IN BACKGROUND. - Rogers Locomotive & Machine Works, Spruce & Market Streets, Paterson, Passaic County, NJ

  15. CAR SHOP TRANSFER TABLE, IN STORAGE AT WEST SIDE OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    CAR SHOP TRANSFER TABLE, IN STORAGE AT WEST SIDE OF SHOPS, WEST END JOURNAL BEARING AND WHEELSET DETAIL, LOOKING NORTHEAST. - Southern Pacific, Sacramento Shops, Pitless Transfer Table, 111 I Street, Sacramento, Sacramento County, CA

  16. AUTOMOTIVE REPAIR SHOP, DETAIL OF MILLS COAL BOILER WITH SCREWFEED ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    AUTOMOTIVE REPAIR SHOP, DETAIL OF MILLS COAL BOILER WITH SCREW-FEED COAL HOPPER ON RIGHT SIDE, WITH SCALE. - Cedar City Automotive Repair Shop, Automotive Repair Shop, 820 North Main Street, Cedar City, Iron County, UT

  17. Lube rack of Automotive and Tractor Repair Shops with Warehousefield ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Lube rack of Automotive and Tractor Repair Shops with Warehouse-field Equipment Repair Shop Building's wall to the right, looking from the south - Kekaha Sugar Company, Automotive and Tractor Repair Shops, 8315 Kekaha Road, Kekaha, Kauai County, HI

  18. AUTOMOTIVE REPAIR SHOP, SLIDING DOOR LEADING TO BOILER ROOM ON ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    AUTOMOTIVE REPAIR SHOP, SLIDING DOOR LEADING TO BOILER ROOM ON SOUTH SIDE OF SOUTH WING. - Cedar City Automotive Repair Shop, Automotive Repair Shop, 820 North Main Street, Cedar City, Iron County, UT

  19. View of south elevation of Automotive and Tractor Repair Shops ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of south elevation of Automotive and Tractor Repair Shops with the Warehouse Fabrication Shop and Stack in the background, looking from the southwest - Kekaha Sugar Company, Automotive and Tractor Repair Shops, 8315 Kekaha Road, Kekaha, Kauai County, HI

  20. AUTOMOTIVE REPAIR SHOP, DETAIL OF BUILDING CORNER (MAIN WING) SHOWING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    AUTOMOTIVE REPAIR SHOP, DETAIL OF BUILDING CORNER (MAIN WING) SHOWING WOOD EAVE AND STUCCO RAKEBOARD ON GABLE END, WITH SCALE. - Cedar City Automotive Repair Shop, Automotive Repair Shop, 820 North Main Street, Cedar City, Iron County, UT

  1. AUTOMOTIVE REPAIR SHOP, DETAIL OF FABRICATING PRESS IN EAST END ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    AUTOMOTIVE REPAIR SHOP, DETAIL OF FABRICATING PRESS IN EAST END OF MAIN WING, WITH SCALE. - Cedar City Automotive Repair Shop, Automotive Repair Shop, 820 North Main Street, Cedar City, Iron County, UT

  2. AUTOMOTIVE REPAIR SHOP, DETAIL OF MILLS COAL BOILER WITH SCREWFEED ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    AUTOMOTIVE REPAIR SHOP, DETAIL OF MILLS COAL BOILER WITH SCREW-FEED COAL HOPPER ON RIGHT SIDE. - Cedar City Automotive Repair Shop, Automotive Repair Shop, 820 North Main Street, Cedar City, Iron County, UT

  3. AUTOMOTIVE REPAIR SHOP, DETAIL OF BUILDING CORNER (MAIN WING) SHOWING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    AUTOMOTIVE REPAIR SHOP, DETAIL OF BUILDING CORNER (MAIN WING) SHOWING WOOD EAVE AND STUCCO RAKEBOARD ON GABLE END. - Cedar City Automotive Repair Shop, Automotive Repair Shop, 820 North Main Street, Cedar City, Iron County, UT

  4. AUTOMOTIVE REPAIR SHOP, SLIDING DOOR LEADING TO BOILER ROOM ON ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    AUTOMOTIVE REPAIR SHOP, SLIDING DOOR LEADING TO BOILER ROOM ON SOUTH SIDE OF SOUTH WING, WITH SCALE. - Cedar City Automotive Repair Shop, Automotive Repair Shop, 820 North Main Street, Cedar City, Iron County, UT

  5. View looking SE inside Electrical Shop Central of Georgia ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View looking SE inside Electrical Shop - Central of Georgia Railway, Savannah Repair Shops & Terminal Facilities, Electrical Shop, Bounded by West Broad, Jones, West Boundary & Hull Streets, Savannah, Chatham County, GA

  6. Detail of large, brick columns and bracket inside Electrical Shop ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail of large, brick columns and bracket inside Electrical Shop - Central of Georgia Railway, Savannah Repair Shops & Terminal Facilities, Electrical Shop, Bounded by West Broad, Jones, West Boundary & Hull Streets, Savannah, Chatham County, GA

  7. Detail of Machine Shop (Bldg. 163) south wall and crane ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail of Machine Shop (Bldg. 163) south wall and crane rail. The overlapped tracks in foreground were used to store wheelsets - Atchison, Topeka, Santa Fe Railroad, Albuquerque Shops, Machine Shop, 908 Second Street, Southwest, Albuquerque, Bernalillo County, NM

  8. 39. LOOKING SOUTH ACROSS THE NORTH PART SHOP TO THE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    39. LOOKING SOUTH ACROSS THE NORTH PART SHOP TO THE LARGE CENTRAL PART SHOP, FROM NEAR THE NORTHEAST CORNER OF BUILDING NO. 1. - United Engineering Company Shipyard, Inspection & Repair Shops, 2900 Main Street, Alameda, Alameda County, CA

  9. View northeast of mould loft and plating cutting shop in ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View northeast of mould loft and plating cutting shop in structural assembly shop (building no. 541) - Naval Base Philadelphia-Philadelphia Naval Shipyard, Structural Assembly Shop, League Island, Philadelphia, Philadelphia County, PA

  10. 43. PROCESS WELDING SHEDS (FABRICATION SHOPS) ON RIGHT, AND TANK ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    43. PROCESS WELDING SHEDS (FABRICATION SHOPS) ON RIGHT, AND TANK BARGE, CRANES, PAINT SHOP AND PIPE/MACHINE SHOP IN BACKGROUND, LOOKING NORTHEAST - Hillman Barge & Construction Company, Paul Thomas Boulevard, Brownsville, Fayette County, PA

  11. 10. VIEW OF BOILER SHOP FROM TOP OF BOX CAR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. VIEW OF BOILER SHOP FROM TOP OF BOX CAR WITH CIRCULAR CAR SHOP IN BACKGROUND LOOKING NORTHEAST. - Baltimore & Ohio Railroad, Mount Clare Shops, South side of Pratt Street between Carey & Poppleton Streets, Baltimore, Independent City, MD

  12. CAR MACHINE SHOP, SECOND FLOOR, LYE TANKS FOR CLEANING METAL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    CAR MACHINE SHOP, SECOND FLOOR, LYE TANKS FOR CLEANING METAL PRIOR TO PLATING, LOOKING SOUTH FROM ATTIC. - Southern Pacific, Sacramento Shops, Car Machine Shop, 111 I Street, Sacramento, Sacramento County, CA

  13. 5. RAILROAD TRRACKS LEADING TO PAINT & REPAIR SHOP; PASSENGER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. RAILROAD TRRACKS LEADING TO PAINT & REPAIR SHOP; PASSENGER CAR SHOP TO THE LEFT - Baltimore & Ohio Railroad, Mount Clare Passenger Car Shop, Southwest corner of Pratt & Poppleton Streets, Baltimore, Independent City, MD

  14. CAR MACHINE SHOP, SECOND FLOOR, PAINT SPRAY ROOM EXTERIOR AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    CAR MACHINE SHOP, SECOND FLOOR, PAINT SPRAY ROOM EXTERIOR AND ATTIC FLOOR SUPPORT COLUMNS AND BEAMS, LOOKING WEST. - Southern Pacific, Sacramento Shops, Car Machine Shop, 111 I Street, Sacramento, Sacramento County, CA

  15. CAR MACHINE SHOP, FIRST FLOOR, DETAIL OF WOOD COLUMN AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    CAR MACHINE SHOP, FIRST FLOOR, DETAIL OF WOOD COLUMN AND INVERTED KING-POST TRUSS TO PROVIDE INCREASED SPAN BETWEEN COLUMNS, LOOKING SOUTH. - Southern Pacific, Sacramento Shops, Car Machine Shop, 111 I Street, Sacramento, Sacramento County, CA

  16. CAR MACHINE SHOP, SECOND FLOOR, LYE TANKS FOR CLEANING METAL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    CAR MACHINE SHOP, SECOND FLOOR, LYE TANKS FOR CLEANING METAL PRIOR TO PLATING, LOOKING SOUTHWEST FROM ATTIC. - Southern Pacific, Sacramento Shops, Car Machine Shop, 111 I Street, Sacramento, Sacramento County, CA

  17. 4. GENERAL VIEW LOOKING WEST AT MACHINE SHOP IN KEYSER. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. GENERAL VIEW LOOKING WEST AT MACHINE SHOP IN KEYSER. OLD TRAIN SHED TO RIGHT OF MACHINE SHOP. - Baltimore & Ohio Railroad, Keyser Machine Shop, State Route 46 Northwest of Spring Street, Keyser, Mineral County, WV

  18. Detail of heating coil for Machine Shop (Bldg. 163) ventilation ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail of heating coil for Machine Shop (Bldg. 163) ventilation system Note portion of fan visible behind coil - Atchison, Topeka, Santa Fe Railroad, Albuquerque Shops, Machine Shop, 908 Second Street, Southwest, Albuquerque, Bernalillo County, NM

  19. 10. Interior view, east shop, ground floor, looking northwest, showing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Interior view, east shop, ground floor, looking northwest, showing hardware storage rooms in tin shop area at right. - Larrabee & Hingston Company, Main Shop Building, 19 Howley Street, Peabody, Essex County, MA

  20. Roadhouse and shops, from Chicago, Burlington and Quincy Railroad mainline, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Roadhouse and shops, from Chicago, Burlington and Quincy Railroad mainline, facing southeast. - Chicago, Burlington & Quincy Railroad, Roundhouse & Shops, Broadway & Spring Streets, Aurora, Kane County, IL

  1. Roadhouse and shops from the Chicago, Burlington and Quincy railroad ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Roadhouse and shops from the Chicago, Burlington and Quincy railroad mainline, facing northeast - Chicago, Burlington & Quincy Railroad, Roundhouse & Shops, Broadway & Spring Streets, Aurora, Kane County, IL

  2. Aircraft assembly shop plant no. 2, view looking east ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Aircraft assembly shop plant no. 2, view looking east - northeast. - Naval Base Philadelphia-Philadelphia Naval Shipyard, Aircraft Assembly Shop Plant, League Island, Philadelphia, Philadelphia County, PA

  3. IDENTIFICATION OF BEST INDICATORS OF PEPTIDE-SPECTRUM MATCH USING A PERMUTATION RESAMPLING APPROACH

    PubMed Central

    AKHTAR, MALIK N.; SOUTHEY, BRUCE R.; ANDRÉN, PER E.; SWEEDLER, JONATHAN V.; RODRIGUEZ-ZAS, SANDRA L.

    2014-01-01

    Various indicators of observed-theoretical spectrum matches were compared and the resulting statistical significance was characterized using permutation resampling. Novel decoy databases built by resampling the terminal positions of peptide sequences were evaluated to identify the conditions for accurate computation of peptide match significance levels. The methodology was tested on real and manually curated tandem mass spectra from peptides across a wide range of sizes. Spectra match indicators from complementary database search programs were profiled and optimal indicators were identified. The combination of the optimal indicator and permuted decoy databases improved the calculation of the peptide match significance compared to the approaches currently implemented in the database search programs that rely on distributional assumptions. Permutation tests using p-values obtained from software-dependent matching scores and E-values outperformed permutation tests using all other indicators. The higher overlap in matches between the database search programs when using end permutation compared to existing approaches confirm the superiority of the end permutation method to identify peptides. The combination of effective match indicators and the end permutation method is recommended for accurate detection of peptides. PMID:25362838

  4. Machine Shop. Performance Objectives. Basic Course.

    ERIC Educational Resources Information Center

    Hilton, Arthur; Lambert, George

    Several intermediate performance objectives and corresponding criterion measures are listed for each of 13 terminal objectives for a high school basic machine shop course. The materials were developed for a 36-week course (2 hours daily) designed to enable students to become familiar with the operation of machine shop equipment, to become familiar…

  5. Product Characteristics and Internet Shopping Intentions.

    ERIC Educational Resources Information Center

    Vijayasarathy, Leo R.

    2002-01-01

    Discussion of electronic commerce and online marketing focuses on an empirical study that investigated differences between Internet shopping intentions for products categorized by cost and tangibility. Highlights include hypotheses; respondent characteristics; results that showed that intentions to shop using the Internet differ by tangibility of…

  6. Machine Shop. Instructor Key. Supplementary Units.

    ERIC Educational Resources Information Center

    Walden, Charles; Cole, Phyllis

    These supplementary units are designed to help students with special needs learn and apply machine shop skills. Nine competencies that are difficult for special needs students to grasp or that would help them get a future job in the field were chosen from the regular machine shop curriculum. Specific objectives for these competencies are listed at…

  7. Machine Shop Projects. Instructor Guide. General Information.

    ERIC Educational Resources Information Center

    Westbrook, Raymond E.

    Developed in Georgia, this manual contains 101 projects for use in machine shop courses, arranged according to a suggested machine shop curriculum. Each project, included in a student workbook, contains complete drawings and instructions for implementation. Tasks are listed under the broad headings of measuring, layout, bench work, saws, drilling,…

  8. Product Characteristics and Internet Shopping Intentions.

    ERIC Educational Resources Information Center

    Vijayasarathy, Leo R.

    2002-01-01

    Discussion of electronic commerce and online marketing focuses on an empirical study that investigated differences between Internet shopping intentions for products categorized by cost and tangibility. Highlights include hypotheses; respondent characteristics; results that showed that intentions to shop using the Internet differ by tangibility of…

  9. How to Shop for Health Insurance

    MedlinePlus

    ... to 2-Year-Old How to Shop for Health Insurance KidsHealth > For Parents > How to Shop for Health Insurance A A A What's in this article? Getting ... seguro médico? In America today, we all need health insurance. You do. Your kids do. It's not a " ...

  10. Machine Shop Projects. Instructor Guide. General Information.

    ERIC Educational Resources Information Center

    Westbrook, Raymond E.

    Developed in Georgia, this manual contains 101 projects for use in machine shop courses, arranged according to a suggested machine shop curriculum. Each project, included in a student workbook, contains complete drawings and instructions for implementation. Tasks are listed under the broad headings of measuring, layout, bench work, saws, drilling,…

  11. School Shopping Tips, 2001-02. [Videotape].

    ERIC Educational Resources Information Center

    Department of Education, Washington, DC. Student Financial Assistance.

    This videotape (running time 18.52 minutes) was produced to help students as they shop for a college or career school. It contains shopping tips for both types of institution and stresses the importance of determining what a student wants to do and learn and then looking carefully at the options for education to achieve these goals. Students are…

  12. Machine Shop. Instructor Key. Supplementary Units.

    ERIC Educational Resources Information Center

    Walden, Charles; Cole, Phyllis

    These supplementary units are designed to help students with special needs learn and apply machine shop skills. Nine competencies that are difficult for special needs students to grasp or that would help them get a future job in the field were chosen from the regular machine shop curriculum. Specific objectives for these competencies are listed at…

  13. Your Shopping Dollar. [Revised.] Money Management.

    ERIC Educational Resources Information Center

    Baran, Nancy H., Ed.; Tarrant, Sharon M., Ed.

    This booklet on shopping, 1 in a series of 12, covers all the basic aspects of personal- and family-money management. Suitable for use by high school and college students as well as adults, this handbook tells how to plan spending, develop shopping skills, and handle consumer problems effectively. Section 1 on consumers and the economy overviews…

  14. Your Shopping Dollar. [Revised.] Money Management.

    ERIC Educational Resources Information Center

    Baran, Nancy H., Ed.; Tarrant, Sharon M., Ed.

    This booklet on shopping, 1 in a series of 12, covers all the basic aspects of personal- and family-money management. Suitable for use by high school and college students as well as adults, this handbook tells how to plan spending, develop shopping skills, and handle consumer problems effectively. Section 1 on consumers and the economy overviews…

  15. Shop Tools. FOS: Fundamentals of Service.

    ERIC Educational Resources Information Center

    John Deere Co., Moline, IL.

    This shop tools manual is one of a series of power mechanics texts and visual aids on servicing of automotive and off-the-road equipment. Materials provide basic information and illustrations for use by vocational students and teachers as well as shop servicemen and laymen. Sections describe the use of the following tools: screwdrivers, hammers,…

  16. Machine Shop. Performance Objectives. Basic Course.

    ERIC Educational Resources Information Center

    Hilton, Arthur; Lambert, George

    Several intermediate performance objectives and corresponding criterion measures are listed for each of 13 terminal objectives for a high school basic machine shop course. The materials were developed for a 36-week course (2 hours daily) designed to enable students to become familiar with the operation of machine shop equipment, to become familiar…

  17. How to Shop for Health Insurance

    MedlinePlus

    ... to 2-Year-Old How to Shop for Health Insurance KidsHealth > For Parents > How to Shop for Health Insurance Print A A A What's in this article? ... seguro médico? In America today, we all need health insurance. You do. Your kids do. It's not a " ...

  18. Predecessor and permutation existence problems for sequential dynamical systems

    SciTech Connect

    Barrett, C. L.; Hunt, H. B.; Marathe, M. V.; Rosenkrantz, D. J.; Stearns, R. E.

    2002-01-01

    A class of finite discrete dynamical systems, called Sequential Dynamical Systems (SDSs), was introduced in BMR99, BR991 as a formal model for analyzing simulation systems. An SDS S is a triple (G, F,n ),w here (i) G(V,E ) is an undirected graph with n nodes with each node having a state, (ii) F = (fi, fi, . . ., fn), with fi denoting a function associated with node ui E V and (iii) A is a permutation of (or total order on) the nodes in V, A configuration of an SDS is an n-vector ( b l, bz, . . ., bn), where bi is the value of the state of node vi. A single SDS transition from one configuration to another is obtained by updating the states of the nodes by evaluating the function associated with each of them in the order given by n. Here, we address the complexity of two basic problems and their generalizations for SDSs. Given an SDS S and a configuration C, the PREDECESSOR EXISTENCE (or PRE) problem is to determine whether there is a configuration C' such that S has a transition from C' to C. (If C has no predecessor, C is known as a garden of Eden configuration.) Our results provide separations between efficiently solvable and computationally intractable instances of the PRE problem. For example, we show that the PRE problem can be solved efficiently for SDSs with Boolean state values when the node functions are symmetric and the underlying graph is of bounded treewidth. In contrast, we show that allowing just one non-symmetric node function renders the problem NP-complete even when the underlying graph is a tree (which has a treewidth of 1). We also show that the PRE problem is efficiently solvable for SDSs whose state values are from a field and whose node functions are linear. Some of the polynomial algorithms also extend to the case where we want to find an ancestor configuration that precedes a given configuration by a logarithmic number of steps. Our results extend some of the earlier results by Sutner [Su95] and Green [@87] on the complexity of the

  19. The structure of a thermophilic kinase shapes fitness upon random circular permutation

    PubMed Central

    Jones, Alicia M.; Mehta, Manan M.; Thomas, Emily E.; Atkinson, Joshua T.; Segall-Shapiro, Thomas H.; Liu, Shirley; Silberg, Jonathan J.

    2016-01-01

    Proteins can be engineered for synthetic biology through circular permutation, a sequence rearrangement where native protein termini become linked and new termini are created elsewhere through backbone fission. However, it remains challenging to anticipate a protein’s functional tolerance to circular permutation. Here, we describe new transposons for creating libraries of randomly circularly permuted proteins that minimize peptide additions at their termini, and we use transposase mutagenesis to study the tolerance of a thermophilic adenylate kinase (AK) to circular permutation. We find that libraries expressing permuted AK with either short or long peptides amended to their N-terminus yield distinct sets of active variants and present evidence that this trend arises because permuted protein expression varies across libraries. Mapping all sites that tolerate backbone cleavage onto AK structure reveals that the largest contiguous regions of sequence that lack cleavage sites are proximal to the phosphotransfer site. A comparison of our results with a range of structure-derived parameters further showed that retention of function correlates to the strongest extent with the distance to the phosphotransfer site, amino acid variability in an AK family sequence alignment, and residue-level deviations in superimposed AK structures. Our work illustrates how permuted protein libraries can be created with minimal peptide additions using transposase mutagenesis, and they reveal a challenge of maintaining consistent expression across permuted variants in a library that minimizes peptide additions. Furthermore, these findings provide a basis for interpreting responses of thermophilic phosphotransferases to circular permutation by calibrating how different structure-derived parameters relate to retention of function in a cellular selection. PMID:26976658

  20. Multiscale permutation entropy analysis of EEG recordings during sevoflurane anesthesia

    NASA Astrophysics Data System (ADS)

    Li, Duan; Li, Xiaoli; Liang, Zhenhu; Voss, Logan J.; Sleigh, Jamie W.

    2010-08-01

    Electroencephalogram (EEG) monitoring of the effect of anesthetic drugs on the central nervous system has long been used in anesthesia research. Several methods based on nonlinear dynamics, such as permutation entropy (PE), have been proposed to analyze EEG series during anesthesia. However, these measures are still single-scale based and may not completely describe the dynamical characteristics of complex EEG series. In this paper, a novel measure combining multiscale PE information, called CMSPE (composite multi-scale permutation entropy), was proposed for quantifying the anesthetic drug effect on EEG recordings during sevoflurane anesthesia. Three sets of simulated EEG series during awake, light and deep anesthesia were used to select the parameters for the multiscale PE analysis: embedding dimension m, lag τ and scales to be integrated into the CMSPE index. Then, the CMSPE index and raw single-scale PE index were applied to EEG recordings from 18 patients who received sevoflurane anesthesia. Pharmacokinetic/pharmacodynamic (PKPD) modeling was used to relate the measured EEG indices and the anesthetic drug concentration. Prediction probability (Pk) statistics and correlation analysis with the response entropy (RE) index, derived from the spectral entropy (M-entropy module; GE Healthcare, Helsinki, Finland), were investigated to evaluate the effectiveness of the new proposed measure. It was found that raw single-scale PE was blind to subtle transitions between light and deep anesthesia, while the CMSPE index tracked these changes accurately. Around the time of loss of consciousness, CMSPE responded significantly more rapidly than the raw PE, with the absolute slopes of linearly fitted response versus time plots of 0.12 (0.09-0.15) and 0.10 (0.06-0.13), respectively. The prediction probability Pk of 0.86 (0.85-0.88) and 0.85 (0.80-0.86) for CMSPE and raw PE indicated that the CMSPE index correlated well with the underlying anesthetic effect. The correlation

  1. Easy transition path sampling methods: flexible-length aimless shooting and permutation shooting.

    PubMed

    Mullen, Ryan Gotchy; Shea, Joan-Emma; Peters, Baron

    2015-06-09

    We present new algorithms for conducting transition path sampling (TPS). Permutation shooting rigorously preserves the total energy and momentum of the initial trajectory and is simple to implement even for rigid water molecules. Versions of aimless shooting and permutation shooting that use flexible-length trajectories have simple acceptance criteria and are more computationally efficient than fixed-length versions. Flexible-length permutation shooting and inertial likelihood maximization are used to identify the reaction coordinate for vacancy migration in a two-dimensional trigonal crystal of Lennard-Jones particles. The optimized reaction coordinate eliminates nearly all recrossing of the transition state dividing surface.

  2. Multi-response permutation procedure as an alternative to the analysis of variance: an SPSS implementation.

    PubMed

    Cai, Li

    2006-02-01

    A permutation test typically requires fewer assumptions than does a comparable parametric counterpart. The multi-response permutation procedure (MRPP) is a class of multivariate permutation tests of group difference useful for the analysis of experimental data. However, psychologists seldom make use of the MRPP in data analysis, in part because the MRPP is not implemented in popular statistical packages that psychologists use. A set of SPSS macros implementing the MRPP test is provided in this article. The use of the macros is illustrated by analyzing example data sets.

  3. Circular permutation of betaB2-crystallin changes the hierarchy of domain assembly.

    PubMed Central

    Wright, G.; Basak, A. K.; Wieligmann, K.; Mayr, E. M.; Slingsby, C.

    1998-01-01

    The betagamma-crystallins form a superfamily of eye lens proteins comprised of multiple Greek motifs that are symmetrically organized into domains and higher assemblies. In the betaB2-crystallin dimer each polypeptide folds into two similar domains that are related to monomeric gamma-crystallin by domain swapping. The crystal structure of the circularly permuted two-domain betaB2 polypeptide shows that permutation converts intermolecular domain pairing into intramolecular pairing. However, the dimeric permuted protein is, in fact, half a native tetramer. This result shows how the sequential order of domains in multi-domain proteins can affect quaternary domain assembly. PMID:9655330

  4. Heat Treat Shop in the Technical Services Building

    NASA Image and Video Library

    1948-01-21

    A technician prepares a metal component for a high-temperature bake in the Heat Treatment Shop at the National Advisory Committee for Aeronautics (NACA) Lewis Flight Propulsion Laboratory. Fabrication Division under Dan White and John Dalgleish created almost all of the equipment and models used at the laboratory. The Technical Services Building, referred to as the Fab Shop, contained a number of specialized shops in the 1940s and 1950s. These included a Machine Shop, Sheet Metal Shop, Wood and Pattern Shop, Instrument Shop, Thermocouple Shop, Heat Treating Shop, Metallurgical Laboratory, and Fabrication Office. The Metallurgical Laboratory contained a control lab for the Heat Treating Shop and a service lab for the NACA Lewis research divisions. This metallurgical group performed tensile and impact tests on metals to determine their suitability for specific research or equipment. The Heat Treating Shop heated metal parts to optimize their physical properties and contained a Precision Castings Foundry to manufacture equipment made of heat resisting alloys.

  5. Inaccuracy, Uncertainty and the Space-Time Permutation Scan Statistic

    PubMed Central

    Malizia, Nicholas

    2013-01-01

    The space-time permutation scan statistic (STPSS) is designed to identify hot (and cool) spots of space-time interaction within patterns of spatio-temporal events. While the method has been adopted widely in practice, there has been little consideration of the effect inaccurate and/or incomplete input data may have on its results. Given the pervasiveness of inaccuracy, uncertainty and incompleteness within spatio-temporal datasets and the popularity of the method, this issue warrants further investigation. Here, a series of simulation experiments using both synthetic and real-world data are carried out to better understand how deficiencies in the spatial and temporal accuracy as well as the completeness of the input data may affect results of the STPSS. The findings, while specific to the parameters employed here, reveal a surprising robustness of the method's results in the face of these deficiencies. As expected, the experiments illustrate that greater degradation of input data quality leads to greater variability in the results. Additionally, they show that weaker signals of space-time interaction are those most affected by the introduced deficiencies. However, in stark contrast to previous investigations into the impact of these input data problems on global tests of space-time interaction, this local metric is revealed to be only minimally affected by the degree of inaccuracy and incompleteness introduced in these experiments. PMID:23408930

  6. Ground states of fermionic lattice Hamiltonians with permutation symmetry

    NASA Astrophysics Data System (ADS)

    Kraus, Christina V.; Lewenstein, Maciej; Cirac, J. Ignacio

    2013-08-01

    We study the ground states of lattice Hamiltonians that are invariant under permutations, in the limit where the number of lattice sites N→∞. For spin systems, these are product states, a fact that follows directly from the quantum de Finetti theorem. For fermionic systems, however, the problem is very different, since mode operators acting on different sites do not commute, but anticommute. We construct a family of fermionic states, F, from which such ground states can be easily computed. They are characterized by few parameters whose number only depends on M, the number of modes per lattice site. We also give an explicit construction for M=1,2. In the first case, F is contained in the set of Gaussian states, whereas in the second it is not. Inspired by that construction, we build a set of fermionic variational wave functions, and apply it to the Fermi-Hubbard model in two spatial dimensions, obtaining results that go beyond the generalized Hartree-Fock theory.

  7. Inaccuracy, uncertainty and the space-time permutation scan statistic.

    PubMed

    Malizia, Nicholas

    2013-01-01

    The space-time permutation scan statistic (STPSS) is designed to identify hot (and cool) spots of space-time interaction within patterns of spatio-temporal events. While the method has been adopted widely in practice, there has been little consideration of the effect inaccurate and/or incomplete input data may have on its results. Given the pervasiveness of inaccuracy, uncertainty and incompleteness within spatio-temporal datasets and the popularity of the method, this issue warrants further investigation. Here, a series of simulation experiments using both synthetic and real-world data are carried out to better understand how deficiencies in the spatial and temporal accuracy as well as the completeness of the input data may affect results of the STPSS. The findings, while specific to the parameters employed here, reveal a surprising robustness of the method's results in the face of these deficiencies. As expected, the experiments illustrate that greater degradation of input data quality leads to greater variability in the results. Additionally, they show that weaker signals of space-time interaction are those most affected by the introduced deficiencies. However, in stark contrast to previous investigations into the impact of these input data problems on global tests of space-time interaction, this local metric is revealed to be only minimally affected by the degree of inaccuracy and incompleteness introduced in these experiments.

  8. Efficiency and credit ratings: a permutation-information-theory analysis

    NASA Astrophysics Data System (ADS)

    Fernandez Bariviera, Aurelio; Zunino, Luciano; Belén Guercio, M.; Martinez, Lisana B.; Rosso, Osvaldo A.

    2013-08-01

    The role of credit rating agencies has been under severe scrutiny after the subprime crisis. In this paper we explore the relationship between credit ratings and informational efficiency of a sample of thirty nine corporate bonds of US oil and energy companies from April 2008 to November 2012. For this purpose we use a powerful statistical tool, relatively new in the financial literature: the complexity-entropy causality plane. This representation space allows us to graphically classify the different bonds according to their degree of informational efficiency. We find that this classification agrees with the credit ratings assigned by Moody’s. In particular, we detect the formation of two clusters, which correspond to the global categories of investment and speculative grades. Regarding the latter cluster, two subgroups reflect distinct levels of efficiency. Additionally, we also find an intriguing absence of correlation between informational efficiency and firm characteristics. This allows us to conclude that the proposed permutation-information-theory approach provides an alternative practical way to justify bond classification.

  9. Circular permutation of a synthetic eukaryotic chromosome with the telomerator

    PubMed Central

    Mitchell, Leslie A.; Boeke, Jef D.

    2014-01-01

    Chromosome engineering is a major focus in the fields of systems biology, genetics, synthetic biology, and the functional analysis of genomes. Here, we describe the “telomerator,” a new synthetic biology device for use in Saccharomyces cerevisiae. The telomerator is designed to inducibly convert circular DNA molecules into mitotically stable, linear chromosomes replete with functional telomeres in vivo. The telomerator cassette encodes convergent yeast telomere seed sequences flanking the I-SceI homing endonuclease recognition site in the center of an intron artificially transplanted into the URA3 selectable/counterselectable auxotrophic marker. We show that inducible expression of the homing endonuclease efficiently generates linear molecules, identified by using a simple plate-based screening method. To showcase its functionality and utility, we use the telomerator to circularly permute a synthetic yeast chromosome originally constructed as a circular molecule, synIXR, to generate 51 linear variants. Many of the derived linear chromosomes confer unexpected phenotypic properties. This finding indicates that the telomerator offers a new way to study the effects of gene placement on chromosomes (i.e., telomere proximity). However, that the majority of synIXR linear derivatives support viability highlights inherent tolerance of S. cerevisiae to changes in gene order and overall chromosome structure. The telomerator serves as an important tool to construct artificial linear chromosomes in yeast; the concept can be extended to other eukaryotes. PMID:25378705

  10. Visualizing Set Concordance with Permutation Matrices and Fan Diagrams

    PubMed Central

    Kim, Bohyoung; Lee, Bongshin

    2007-01-01

    Scientific problem solving often involves concordance (or discordance) analysis among the result sets from different approaches. For example, different scientific analysis methods with the same samples often lead to different or even conflicting conclusions. To reach a more judicious conclusion, it is crucial to consider different perspectives by checking concordance among those result sets by different methods. In this paper, we present an interactive visualization tool called ConSet, where users can effectively examine relationships among multiple sets at once. ConSet provides an overview using an improved permutation matrix to enable users to easily identify relationships among sets with a large number of elements. Not only do we use a standard Venn diagram, we also introduce a new diagram called Fan diagram that allows users to compare two or three sets without any inconsistencies that may exist in Venn diagrams. A qualitative user study was conducted to evaluate how our tool works in comparison with a traditional set visualization tool based on a Venn diagram. We observed that ConSet enabled users to complete more tasks with fewer errors than the traditional interface did and most users preferred ConSet. PMID:19641637

  11. An Optimal Parallel Algorithm for Constructing a Spanning Tree on Circular Permutation Graphs

    NASA Astrophysics Data System (ADS)

    Honma, Hirotoshi; Honma, Saki; Masuyama, Shigeru

    The spanning tree problem is to find a tree that connects all the vertices of G. This problem has many applications, such as electric power systems, computer network design and circuit analysis. Klein and Stein demonstrated that a spanning tree can be found in O(log n) time with O(n + m) processors on the CRCW PRAM. In general, it is known that more efficient parallel algorithms can be developed by restricting classes of graphs. Circular permutation graphs properly contain the set of permutation graphs as a subclass and are first introduced by Rotem and Urrutia. They provided O(n2.376) time recognition algorithm. Circular permutation graphs and their models find several applications in VLSI layout. In this paper, we propose an optimal parallel algorithm for constructing a spanning tree on circular permutation graphs. It runs in O(log n) time with O(n/ log n) processors on the EREW PRAM.

  12. Dermatoses among floral shop workers.

    PubMed

    Thiboutot, D M; Hamory, B H; Marks, J G

    1990-01-01

    Concern about the increasing incidence of hand dermatitis in floral shop workers in the United States and its possible association to the plant Alstroemeria, a flower that has become popular since its introduction in 1981, prompted investigation of the prevalence and cause of hand dermatitis in a sample of floral workers. Fifty-seven floral workers were surveyed, and 15 (26%) reported hand dermatitis within the previous 12 months. Sixteen floral workers (eight with dermatitis) volunteered to be patch tested to the North American Contact Dermatitis Group Standard and Perfume Trays, a series of eight pesticides and 20 plant allergens. Of four of seven floral designers and arrangers who reported hand dermatitis, three reacted positively to patch tests to tuliposide A, the allergen in Alstroemeria. Patch test readings for all other plant extracts were negative. A positive reading for a test to one pesticide, difolatan (Captafol), was noted, the relevance of which is unknown.

  13. Food shopping behaviours and exposure to discrimination.

    PubMed

    Zenk, Shannon N; Schulz, Amy J; Israel, Barbara A; Mentz, Graciela; Miranda, Patricia Y; Opperman, Alisha; Odoms-Young, Angela M

    2014-05-01

    The present study examined food shopping behaviours, particularly distance to grocery shop, and exposure to discrimination. Cross-sectional observational study utilizing data from a community survey, neighbourhood food environment observations and the decennial census. Three communities in Detroit, Michigan, USA. Probability sample of 919 African-American, Latino and white adults in 146 census blocks and sixty-nine census block groups. On average, respondents shopped for groceries 3·1 miles (4·99 km) from home, with 30·9 % shopping within 1 mile (1·61 km) and 22·3 % shopping more than 5 miles (8·05 km) from home. Longer distance to shop was associated with being younger, African-American (compared with Latino), a woman, higher socio-economic status, lower satisfaction with the neighbourhood food environment, and living in a neighbourhood with higher poverty, without a large grocery store and further from the nearest supermarket. African-Americans and those with the lowest incomes were particularly likely to report unfair treatment at food outlets. Each mile (1·61 km) increase in distance to shop was associated with a 7 % increase in the odds of unfair treatment; this relationship did not differ by race/ethnicity. The study suggests that unfair treatment in retail interactions warrants investigation as a pathway by which restricted neighbourhood food environments and food shopping behaviours may adversely affect health and contribute to health disparities. Efforts to promote 'healthy' and equitable food environments should emphasize local availability and affordability of a range of healthy food products, as well as fair treatment while shopping regardless of race/ethnicity or socio-economic status.

  14. Accurate Assignment of Significance to Neuropeptide Identifications Using Monte Carlo K-Permuted Decoy Databases

    PubMed Central

    Andrén, Per E.; Sweedler, Jonathan V.; Rodriguez-Zas, Sandra L.

    2014-01-01

    In support of accurate neuropeptide identification in mass spectrometry experiments, novel Monte Carlo permutation testing was used to compute significance values. Testing was based on k-permuted decoy databases, where k denotes the number of permutations. These databases were integrated with a range of peptide identification indicators from three popular open-source database search software (OMSSA, Crux, and X! Tandem) to assess the statistical significance of neuropeptide spectra matches. Significance p-values were computed as the fraction of the sequences in the database with match indicator value better than or equal to the true target spectra. When applied to a test-bed of all known manually annotated mouse neuropeptides, permutation tests with k-permuted decoy databases identified up to 100% of the neuropeptides at p-value < 10−5. The permutation test p-values using hyperscore (X! Tandem), E-value (OMSSA) and Sp score (Crux) match indicators outperformed all other match indicators. The robust performance to detect peptides of the intuitive indicator “number of matched ions between the experimental and theoretical spectra” highlights the importance of considering this indicator when the p-value was borderline significant. Our findings suggest permutation decoy databases of size 1×105 are adequate to accurately detect neuropeptides and this can be exploited to increase the speed of the search. The straightforward Monte Carlo permutation testing (comparable to a zero order Markov model) can be easily combined with existing peptide identification software to enable accurate and effective neuropeptide detection. The source code is available at http://stagbeetle.animal.uiuc.edu/pepshop/MSMSpermutationtesting. PMID:25329667

  15. 48 CFR 252.227-7033 - Rights in shop drawings.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Rights in shop drawings... of Provisions And Clauses 252.227-7033 Rights in shop drawings. As prescribed in 227.7107-(1)(c), use the following clause: Rights in Shop Drawings (APR 1966) (a) Shop drawings for construction...

  16. 1. AERIAL VIEW OF SHOPS COMPLEX LOOKING EAST SHOWING WEST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. AERIAL VIEW OF SHOPS COMPLEX LOOKING EAST SHOWING WEST AND EAST ROUNDHOUSES, FROG AND SWITCH SHOP, AND MACHINE SHOP. - Baltimore & Ohio Railroad, Martinsburg Repair Shops, West Side of Tuscarora Creek Opposite East End of Race Street, Martinsburg, Berkeley County, WV

  17. Looking north along east side of roundhouse and shops, superintendent's ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Looking north along east side of roundhouse and shops, superintendent's office at left, taken from the water towers along broadway. Locomotive blacksmith shop in right center distance with car department shops beyond, most likely taken in 1898 - Chicago, Burlington & Quincy Railroad, Roundhouse & Shops, Broadway & Spring Streets, Aurora, Kane County, IL

  18. 10. Interior, Boiler Room, Roundhouse Machine Shop Extension, Southern Pacific ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Interior, Boiler Room, Roundhouse Machine Shop Extension, Southern Pacific Railroad Carlin Shops, view to northwest (90mm lens). The silver stacks suspended from the ceiling in the background mark the former location of the boilers, and served as steam vents. - Southern Pacific Railroad, Carlin Shops, Roundhouse Machine Shop Extension, Foot of Sixth Street, Carlin, Elko County, NV

  19. Youth Clothes-Shopping Behavior: An Analysis by Gender.

    ERIC Educational Resources Information Center

    Peters, John F.

    1989-01-01

    Explored possible gender differences in clothes-shopping behavior among adolescents. Findings from 387 college students revealed that: parents financially assisted sons and daughters equally; there was no gender difference in shopping frequency; mothers more frequently shopped with sons than with daughters; fathers rarely shopped with any…

  20. 9. Detail, sign at east comer of Roundhouse Machine Shop ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. Detail, sign at east comer of Roundhouse Machine Shop Extension, Southern Pacific Railroad Carlin Shops, view to northwest (210mm lens). Sign reads, 'Open Valve To Supply Water To City.' The railroad could supply water to all of Carlin. - Southern Pacific Railroad, Carlin Shops, Roundhouse Machine Shop Extension, Foot of Sixth Street, Carlin, Elko County, NV

  1. VIEW NORTH EXTREME LEFTBUILDING 32; MACHINE SHOP (1890) SECOND LEFTBUILDING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW NORTH- EXTREME LEFT-BUILDING 32; MACHINE SHOP (1890) SECOND LEFT-BUILDING 31; RIGGER SHOP (1890) CENTER- BUILDING 28; BLACKSMITH SHOP (1885) CENTER RIGHT-BUILDING 27; PATTERN SHOP (C.1853) RIGHT-BUILDING 40; WIRE WAREHOUSE (1915) - John A. Roebling's Sons Company & American Steel & Wire Company, South Broad, Clark, Elmer, Mott & Hudson Streets, Trenton, Mercer County, NJ

  2. Detail of north end of the Electrical Shop (foreground) and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail of north end of the Electrical Shop (foreground) and Sheet Metal Shop, note the metal-frame windows in the Electrical Shop, view facing east - Kahului Cannery, Plant No. 28, Boiler House, Sheet Metal and Electrical Shops, 120 Kane Street, Kahului, Maui County, HI

  3. CAR MACHINE SHOP, FIRST FLOOR, DETAIL OF STEEL COLUMN AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    CAR MACHINE SHOP, FIRST FLOOR, DETAIL OF STEEL COLUMN AND BEAM ALTERATION, LOOKING SOUTH. MODIFICATION WAS DONE TO ACCOMMODATE MACHINERY DURING THE BUILDING'S USE AS A WHEEL SHOP. - Southern Pacific, Sacramento Shops, Car Machine Shop, 111 I Street, Sacramento, Sacramento County, CA

  4. Looking west at Machine Shop (Bldg. 163) south bay interior. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Looking west at Machine Shop (Bldg. 163) south bay interior. Note the Shaw 15-ton bridge crane. This portion of the building housed machine tools and locomotive component repair functions that supported the erecting shop operations - Atchison, Topeka, Santa Fe Railroad, Albuquerque Shops, Machine Shop, 908 Second Street, Southwest, Albuquerque, Bernalillo County, NM

  5. Circularly permuted green fluorescent proteins engineered to sense Ca2+.

    PubMed

    Nagai, T; Sawano, A; Park, E S; Miyawaki, A

    2001-03-13

    To visualize Ca(2+)-dependent protein-protein interactions in living cells by fluorescence readouts, we used a circularly permuted green fluorescent protein (cpGFP), in which the amino and carboxyl portions had been interchanged and reconnected by a short spacer between the original termini. The cpGFP was fused to calmodulin and its target peptide, M13. The chimeric protein, which we have named "pericam," was fluorescent and its spectral properties changed reversibly with the amount of Ca(2+), probably because of the interaction between calmodulin and M13 leading to an alteration of the environment surrounding the chromophore. Three types of pericam were obtained by mutating several amino acids adjacent to the chromophore. Of these, "flash-pericam" became brighter with Ca(2+), whereas "inverse-pericam" dimmed. On the other hand, "ratiometric-pericam" had an excitation wavelength changing in a Ca(2+)-dependent manner. All of the pericams expressed in HeLa cells were able to monitor free Ca(2+) dynamics, such as Ca(2+) oscillations in the cytosol and the nucleus. Ca(2+) imaging using high-speed confocal line-scanning microscopy and a flash-pericam allowed to detect the free propagation of Ca(2+) ions across the nuclear envelope. Then, free Ca(2+) concentrations in the nucleus and mitochondria were simultaneously measured by using ratiometric-pericams having appropriate localization signals, revealing that extra-mitochondrial Ca(2+) transients caused rapid changes in the concentration of mitochondrial Ca(2+). Finally, a "split-pericam" was made by deleting the linker in the flash-pericam. The Ca(2+)-dependent interaction between calmodulin and M13 in HeLa cells was monitored by the association of the two halves of GFP, neither of which was fluorescent by itself.

  6. 6. North wall and east end of air brake shop ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. North wall and east end of air brake shop section of roundhouse at center. East end of boiler shop section of roundhouse to the right of air brake shop. East end of blacksmith shop section of roundhouse at far right. View to southeast. - Duluth & Iron Range Rail Road Company Shops, Roundhouse, Southwest of downtown Two Harbors, northwest of Agate Bay, Two Harbors, Lake County, MN

  7. 3. Oblique view of southwest end, Roundhouse Machine Shop Extension, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Oblique view of southwest end, Roundhouse Machine Shop Extension, Southern Pacific Railroad Carlin Shops, view to north showing the curvature of the end wall that was the common wall with the Roundhouse, and the large metal-clad doors through which steam locomotives were moved into the Machine Shop (135mm lens). - Southern Pacific Railroad, Carlin Shops, Roundhouse Machine Shop Extension, Foot of Sixth Street, Carlin, Elko County, NV

  8. ShopComm: Community-Supported Online Shopping for Older Adults.

    PubMed

    Gorkovenko, Katerina; Tigwell, Garreth W; Norrie, Christopher S; Waite, Miriam; Herron, Daniel

    2017-01-01

    The United Kingdom has an ageing population whose members experience significant life transitions as they grow older, for example, losing mobility due to deteriorating health. For these adults, digital technology has the potential to sustain their independence and improve their quality of life. However older adults can be reluctant to use digital solutions. In this paper, we review a local charity providing a grocery shopping service for older adults who are unable to go themselves. We explore how older adults perceive the benefits and drawbacks of both physical and digital shopping. Using these insights, we designed ShopComm to enable and support older adults with mobility impairments to shop online.

  9. Profiling the Shopping Behavior of Elderly Consumers.

    ERIC Educational Resources Information Center

    Mason, J. Barry; Bearden, William O.

    1978-01-01

    Data were collected by personal interview on shopping roles, information processing, food stamp and coupon use, store brand purchases, mispricing and product unavailability experiences, and with familiarity with fair trade practices. Implications and directions for further research are suggested. (Author)

  10. Profiling the Shopping Behavior of Elderly Consumers.

    ERIC Educational Resources Information Center

    Mason, J. Barry; Bearden, William O.

    1978-01-01

    Data were collected by personal interview on shopping roles, information processing, food stamp and coupon use, store brand purchases, mispricing and product unavailability experiences, and with familiarity with fair trade practices. Implications and directions for further research are suggested. (Author)

  11. Shopping Parents: Patient Problem or Professional Problem?

    ERIC Educational Resources Information Center

    Keirn, William C.

    1971-01-01

    A survey of parents of retarded children showed less than 3 per cent of the parents were shopping parents, defined as those who pursue a third professional evaluation after receiving at least two others on previous occasions. (KW)

  12. Food Shopping Behaviors and Exposure to Discrimination

    PubMed Central

    Zenk, Shannon N.; Schulz, Amy J.; Israel, Barbara A.; Mentz, Graciela; Miranda, Patricia Y.; Opperman, Alisha; Odoms-Young, Angela M.

    2013-01-01

    Objective This study examined food shopping behaviors, particularly distance to grocery shop, and exposure to discrimination. Design Cross-sectional observational study utilizing data from a community survey, neighborhood food environment observations, and the decennial census. Setting Three communities in Detroit, Michigan, USA. Subjects Probability sample of 919 African-American, Latino, and White adults in 146 census blocks and 69 census block groups. Results On average, respondents shopped for groceries 3·1 miles from home, with 30·9% shopping within one mile and 22·3% more than five miles from home. Longer distance to shop was associated with being younger, African-American (compared to Latino), a woman, higher socioeconomic status, lower satisfaction with the neighborhood food environment, and living in a neighborhood with higher poverty, without a large grocery store, and farther from the nearest supermarket. African-Americans and those with the lowest incomes were particularly likely to report unfair treatment at food outlets. Each mile increase in distance to shop was associated with a 7% increase in the odds of unfair treatment; this relationship did not differ by race/ethnicity. Conclusions This study suggests that unfair treatment in retail interactions warrants investigation as a pathway by which restricted neighborhood food environments and food shopping behaviors may adversely affect health and contribute to health disparities. Efforts to promote “healthy” and equitable food environments should emphasize local availability and affordability of a range of healthy food products, as well as fair treatment while shopping regardless of race/ethnicity or socioeconomic status. PMID:23534814

  13. Doctor shopping: a phenomenon of many themes.

    PubMed

    Sansone, Randy A; Sansone, Lori A

    2012-11-01

    Doctor shopping is defined as seeing multiple treatment providers, either during a single illness episode or to procure prescription medications illicitly. According to the available literature, prevalence rates of doctor shopping vary widely, from 6.3 to 56 percent. However, this variability is partially attributable to research methodology, including the study definition of doctor shopping as well as the patient sample. The reasons for doctor shopping are varied. Some patient explanations for this phenomenon relate to clinician factors, such as inconvenient office hours or locations, long waiting times, personal characteristics or qualities of the provider, and/or insufficient communication time between the patient and clinician. Some patient explanations relate to personal factors and include both illness factors (e.g., symptom persistence, lack of understanding or nonacceptance of the diagnosis or treatment) as well as psychological factors (e.g., somatization, prescription drug-seeking). Importantly, not all doctor shopping is driven by suspect motivations. Being aware of these various patient justifications for doctor shopping is important in understanding and managing these challenging patients in the clinical setting, whether they emerge in psychiatric or primary care environments.

  14. Healthful grocery shopping. Perceptions and barriers.

    PubMed

    Hollywood, Lynsey E; Cuskelly, Geraldine J; O'Brien, Michelle; McConnon, Aine; Barnett, Julie; Raats, Monique M; Dean, Moira

    2013-11-01

    While there is evidence of the factors influencing the healthfulness of consumers' food choice, little is known about how consumers perceive the healthfulness of their shopping. This study aimed to explore consumers' perceptions of, and identify barriers to, conducting a healthful shop. Using a qualitative approach, consisting of an accompanied shop and post-shop telephone interview, 50 grocery shoppers were recruited. Results showed that consumers used three criteria to identify a healthful shop: (1) inclusion of healthful foods; (2) avoidance or restriction of particular foods; and (3) achieving a balance between healthful and unhealthful foods. Those who take a balanced approach employ a more holistic approach to their diet while those who avoid or include specific foods may be setting criteria to purchase only certain types of food. The effectiveness of any of these strategies in improving healthfulness is still unclear and requires further investigation. Two barriers to healthful shopping were: (i) lack of self-efficacy in choosing, preparing and cooking healthful foods and (ii) conflicting needs when satisfying self and others. This highlights the need for interventions targeted at building key food skills and for manufacturers to make healthful choices more appealing. Copyright © 2013 Elsevier Ltd. All rights reserved.

  15. Electromyographic Permutation Entropy Quantifies Diaphragmatic Denervation and Reinnervation

    PubMed Central

    Kretschmer, Alexander; Lehmeyer, Veronika; Kellermann, Kristine; Schaller, Stephan J.; Blobner, Manfred; Kochs, Eberhard F.; Fink, Heidrun

    2014-01-01

    Spontaneous reinnervation after diaphragmatic paralysis due to trauma, surgery, tumors and spinal cord injuries is frequently observed. A possible explanation could be collateral reinnervation, since the diaphragm is commonly double-innervated by the (accessory) phrenic nerve. Permutation entropy (PeEn), a complexity measure for time series, may reflect a functional state of neuromuscular transmission by quantifying the complexity of interactions across neural and muscular networks. In an established rat model, electromyographic signals of the diaphragm after phrenicotomy were analyzed using PeEn quantifying denervation and reinnervation. Thirty-three anesthetized rats were unilaterally phrenicotomized. After 1, 3, 9, 27 and 81 days, diaphragmatic electromyographic PeEn was analyzed in vivo from sternal, mid-costal and crural areas of both hemidiaphragms. After euthanasia of the animals, both hemidiaphragms were dissected for fiber type evaluation. The electromyographic incidence of an accessory phrenic nerve was 76%. At day 1 after phrenicotomy, PeEn (normalized values) was significantly diminished in the sternal (median: 0.69; interquartile range: 0.66–0.75) and mid-costal area (0.68; 0.66–0.72) compared to the non-denervated side (0.84; 0.78–0.90) at threshold p<0.05. In the crural area, innervated by the accessory phrenic nerve, PeEn remained unchanged (0.79; 0.72–0.86). During reinnervation over 81 days, PeEn normalized in the mid-costal area (0.84; 0.77–0.86), whereas it remained reduced in the sternal area (0.77; 0.70–0.81). Fiber type grouping, a histological sign for reinnervation, was found in the mid-costal area in 20% after 27 days and in 80% after 81 days. Collateral reinnervation can restore diaphragm activity after phrenicotomy. Electromyographic PeEn represents a new, distinctive assessment characterizing intramuscular function following denervation and reinnervation. PMID:25532023

  16. MATC Machine Shop '84: Specific Skill Needs Assessment for Machine Shops in the Milwaukee Area.

    ERIC Educational Resources Information Center

    Roberts, Keith J.

    Building on previous research on the future skill needs of workers in southeastern Wisconsin, a study was conducted at Milwaukee Area Technical College (MATC) to gather information on the machine tool industry in the Milwaukee area. Interviews were conducted by MATC Machine Shop and Tool and Die faculty with representatives from 135 machine shops,…

  17. A Versatile Platform for Nanotechnology Based on Circular Permutation of a Chaperonin Protein

    NASA Technical Reports Server (NTRS)

    Paavola, Chad; McMillan, Andrew; Trent, Jonathan; Chan, Suzanne; Mazzarella, Kellen; Li, Yi-Fen

    2004-01-01

    A number of protein complexes have been developed as nanoscale templates. These templates can be functionalized using the peptide sequences that bind inorganic materials. However, it is difficult to integrate peptides into a specific position within a protein template. Integrating intact proteins with desirable binding or catalytic activities is an even greater challenge. We present a general method for modifying protein templates using circular permutation so that additional peptide sequence can be added in a wide variety of specific locations. Circular permutation is a reordering of the polypeptide chain such that the original termini are joined and new termini are created elsewhere in the protein. New sequence can be joined to the protein termini without perturbing the protein structure and with minimal limitation on the size and conformation of the added sequence. We have used this approach to modify a chaperonin protein template, placing termini at five different locations distributed across the surface of the protein complex. These permutants are competent to form the double-ring structures typical of chaperonin proteins. The permuted double-rings also form the same assemblies as the unmodified protein. We fused a fluorescent protein to two representative permutants and demonstrated that it assumes its active structure and does not interfere with assembly of chaperonin double-rings.

  18. A novel chaos-based bit-level permutation scheme for digital image encryption

    NASA Astrophysics Data System (ADS)

    Fu, Chong; Lin, Bin-bin; Miao, Yu-sheng; Liu, Xiao; Chen, Jun-jie

    2011-11-01

    Confidentiality is an important issue when digital images are transmitted over public networks, and encryption is the most useful technique employed for this purpose. Image encryption is somehow different from text encryption due to some inherent features of image such as bulk data capacity and high correlation among pixels, which are generally difficult to handle by conventional algorithms. Recently, chaos-based encryption has suggested a new and efficient way to deal with the intractable problems of fast and highly secure image encryption. This paper proposes a novel chaos-based bit-level permutation scheme for secure and efficient image cipher. To overcome the drawbacks of conventional permutation-only type image cipher, the proposed scheme introduced a significant diffusion effect in permutation procedure through a two-stage bit-level shuffling algorithm. The two-stage permutation operations are realized by chaotic sequence sorting algorithm and Arnold Cat map, respectively. Results of various types of analysis are interesting and indicate that the security level of the new scheme is competitive with that of permutation-diffusion type image cipher, while the computational complexity is much lower. Therefore the new scheme is a good candidate for real-time secure image communication applications.

  19. A Versatile Platform for Nanotechnology Based on Circular Permutation of a Chaperonin Protein

    NASA Technical Reports Server (NTRS)

    Paavola, Chad; McMillan, Andrew; Trent, Jonathan; Chan, Suzanne; Mazzarella, Kellen; Li, Yi-Fen

    2004-01-01

    A number of protein complexes have been developed as nanoscale templates. These templates can be functionalized using the peptide sequences that bind inorganic materials. However, it is difficult to integrate peptides into a specific position within a protein template. Integrating intact proteins with desirable binding or catalytic activities is an even greater challenge. We present a general method for modifying protein templates using circular permutation so that additional peptide sequence can be added in a wide variety of specific locations. Circular permutation is a reordering of the polypeptide chain such that the original termini are joined and new termini are created elsewhere in the protein. New sequence can be joined to the protein termini without perturbing the protein structure and with minimal limitation on the size and conformation of the added sequence. We have used this approach to modify a chaperonin protein template, placing termini at five different locations distributed across the surface of the protein complex. These permutants are competent to form the double-ring structures typical of chaperonin proteins. The permuted double-rings also form the same assemblies as the unmodified protein. We fused a fluorescent protein to two representative permutants and demonstrated that it assumes its active structure and does not interfere with assembly of chaperonin double-rings.

  20. Modulation of a protein free-energy landscape by circular permutation.

    PubMed

    Radou, Gaël; Enciso, Marta; Krivov, Sergei; Paci, Emanuele

    2013-11-07

    Circular permutations usually retain the native structure and function of a protein while inevitably perturbing its folding dynamics. By using simulations with a structure-based model and a rigorous methodology to determine free-energy surfaces from trajectories, we evaluate the effect of a circular permutation on the free-energy landscape of the protein T4 lysozyme. We observe changes which, although subtle, largely affect the cooperativity between the two subdomains. Such a change in cooperativity has been previously experimentally observed and recently also characterized using single molecule optical tweezers and the Crooks relation. The free-energy landscapes show that both the wild type and circular permutant have an on-pathway intermediate, previously experimentally characterized, in which one of the subdomains is completely formed. The landscapes, however, differ in the position of the rate-limiting step for folding, which occurs before the intermediate in the wild type and after in the circular permutant. This shift of transition state explains the observed change in the cooperativity. The underlying free-energy landscape thus provides a microscopic description of the folding dynamics and the connection between circular permutation and the loss of cooperativity experimentally observed.

  1. Vape Shop Employees: Public Health Advocates?

    PubMed Central

    Hart, Joy L; Walker, Kandi L; Sears, Clara G; Lee, Alexander S; Smith, Courteney; Siu, Allison; Keith, Rachel; Ridner, S. Lee

    2017-01-01

    INTRODUCTION E-cigarettes have increased in popularity and given rise to a new type of sales outlet—the vape shop. Expanding on work examining vape shop employee e-cigarette and tobacco attitudes and behaviors1, this study examined key messages that vape shop employees communicate to customers. METHODS Using informal interviews, observations, and a cross-sectional survey, we examined vape shop employees’ (n=16) perceptions and e-cigarette use. Data were collected in nine vape shops in Louisville, Kentucky. We used open coding to analyze the qualitative interviews, observation notes, and open-ended survey responses. Descriptive statistics were used to analyze survey data. RESULTS The findings revealed that nearly all employees were former smokers (93.8%), who now only use e-cigarettes. Over one-third of the employees (37.5%) began using e-cigarettes as a replacement for traditional cigarettes, and 93.8% reported better health (e.g., easier breathing, less coughing) since starting to use e-cigarettes. Although most employees believed e-cigarettes should be regulated, 56.3% thought regulations should be different from those governing traditional cigarettes. Analysis of qualitative data revealed that employees see themselves as health advocates who: 1) provide instructions on vaping and promote a vape community, 2) encourage cessation of traditional cigarettes, and 3) support some regulations. CONCLUSIONS The findings reveal that vape shop employees regard e-cigarettes as viable smoking cessation tools and relish their role in assisting others in taking what employees view as positive health actions. Future research addressing communication between vape shop employees and customers, especially related to smoking cessation and health, is needed. PMID:28725875

  2. Security enhanced optical encryption system by random phase key and permutation key.

    PubMed

    He, Mingzhao; Tan, Qiaofeng; Cao, Liangcai; He, Qingsheng; Jin, Guofan

    2009-12-07

    Conventional double random phase encoding (DRPE) encrypts plaintext to white noise-like ciphertext which may attract attention of eavesdroppers, and recent research reported that DRPE is vulnerable to various attacks. Here we propose a security enhanced optical encryption system that can hide the existence of secret information by watermarking. The plaintext is encrypted using iterative fractional Fourier transform with random phase key, and ciphertext is randomly permuted with permutation key before watermarking. Cryptanalysis shows that linearity of the security system has been broken and the permutation key prevent the attacker from accessing the ciphertext in various attacks. A series of simulations have shown the effectiveness of this system and the security strength is enhanced for invisibility, nonlinearity and resistance against attacks.

  3. A rewired green fluorescent protein: folding and function in a nonsequential, noncircular GFP permutant.

    PubMed

    Reeder, Philippa J; Huang, Yao-Ming; Dordick, Jonathan S; Bystroff, Christopher

    2010-12-28

    The sequential order of secondary structural elements in proteins affects the folding and activity to an unknown extent. To test the dependence on sequential connectivity, we reconnected secondary structural elements by their solvent-exposed ends, permuting their sequential order, called "rewiring". This new protein design strategy changes the topology of the backbone without changing the core side chain packing arrangement. While circular and noncircular permutations have been observed in protein structures that are not related by sequence homology, to date no one has attempted to rationally design and construct a protein with a sequence that is noncircularly permuted while conserving three-dimensional structure. Herein, we show that green fluorescent protein can be rewired, still functionally fold, and exhibit wild-type fluorescence excitation and emission spectra.

  4. A Noncommutative de Finetti Theorem: Invariance under Quantum Permutations is Equivalent to Freeness with Amalgamation

    NASA Astrophysics Data System (ADS)

    Köstler, Claus; Speicher, Roland

    2009-10-01

    We show that the classical de Finetti theorem has a canonical noncommutative counterpart if we strengthen “exchangeability” (i.e., invariance of the joint distribution of the random variables under the action of the permutation group) to invariance under the action of the quantum permutation group. More precisely, for an infinite sequence of noncommutative random variables {(x_i)_{iinmathbb{N}}} , we prove that invariance of the joint distribution of the x i ’s under quantum permutations is equivalent to the fact that the x i ’s are identically distributed and free with respect to the conditional expectation onto the tail algebra of the x i ’s.

  5. Analysis of p300/CBP histone acetyltransferase regulation using circular permutation and semisynthesis.

    PubMed

    Karukurichi, Kannan R; Wang, Ling; Uzasci, Lerna; Manlandro, Cara Marie; Wang, Qing; Cole, Philip A

    2010-02-03

    The histone acetyltransferase (HAT) p300/CBP has been shown to undergo autoacetylation on lysines in an apparent regulatory loop that stimulates HAT activity. Here we have developed a strategy to introduce acetyl-Lys at up to six known modification sites in p300/CBP HAT using a combination of circular permutation and expressed protein ligation. We show that these semisynthetic, circularly permuted acetylated proteins retain high affinity for an acetyl-CoA substrate analogue and that HAT activity correlates positively with degree of acetylation. This study provides novel evidence for control of p300/CBP HAT activity by site-specific autoacetylation and outlines a potentially general strategy for using expressed protein ligation and circular permutation to chemically interrogate internal regions of proteins.

  6. Multiple comparisons permutation test for image based data mining in radiotherapy.

    PubMed

    Chen, Chun; Witte, Marnix; Heemsbergen, Wilma; van Herk, Marcel

    2013-12-23

    : Comparing incidental dose distributions (i.e. images) of patients with different outcomes is a straightforward way to explore dose-response hypotheses in radiotherapy. In this paper, we introduced a permutation test that compares images, such as dose distributions from radiotherapy, while tackling the multiple comparisons problem. A test statistic Tmax was proposed that summarizes the differences between the images into a single value and a permutation procedure was employed to compute the adjusted p-value. We demonstrated the method in two retrospective studies: a prostate study that relates 3D dose distributions to failure, and an esophagus study that relates 2D surface dose distributions of the esophagus to acute esophagus toxicity. As a result, we were able to identify suspicious regions that are significantly associated with failure (prostate study) or toxicity (esophagus study). Permutation testing allows direct comparison of images from different patient categories and is a useful tool for data mining in radiotherapy.

  7. Permutational distribution of the log-rank statistic under random censorship with applications to carcinogenicity assays.

    PubMed

    Heimann, G; Neuhaus, G

    1998-03-01

    In the random censorship model, the log-rank test is often used for comparing a control group with different dose groups. If the number of tumors is small, so-called exact methods are often applied for computing critical values from a permutational distribution. Two of these exact methods are discussed and shown to be incorrect. The correct permutational distribution is derived and studied with respect to its behavior under unequal censoring in the light of recent results proving that the permutational version and the unconditional version of the log-rank test are asymptotically equivalent even under unequal censoring. The log-rank test is studied by simulations of a realistic scenario from a bioassay with small numbers of tumors.

  8. Permutation entropy and statistical complexity in characterising low-aspect-ratio reversed-field pinch plasma

    NASA Astrophysics Data System (ADS)

    Onchi, T.; Fujisawa, A.; Sanpei, A.; Himura, H.; Masamune, S.; RELAX Team

    2017-05-01

    Permutation entropy and statistical complexity are measures for complex time series. The Bandt-Pompe methodology evaluates probability distribution using permutation. The method is robust and effective to quantify information of time series data. Statistical complexity is the product of Jensen-Shannon divergence and permutation entropy. These physical parameters are introduced to analyse time series of emission and magnetic fluctuations in low-aspect-ratio reversed-field pinch (RFP) plasma. The observed time-series data aggregates in a region of the plane, the so-called C-H plane, determined by entropy versus complexity. The C-H plane is a representation space used for distinguishing periodic, chaos, stochastic and noisy processes of time series data. The characteristics of the emissions and magnetic fluctuation change under different RFP-plasma conditions. The statistical complexities of soft x-ray emissions and magnetic fluctuations depend on the relationships between reversal and pinch parameters.

  9. Multiple comparisons permutation test for image based data mining in radiotherapy

    PubMed Central

    2013-01-01

    Comparing incidental dose distributions (i.e. images) of patients with different outcomes is a straightforward way to explore dose-response hypotheses in radiotherapy. In this paper, we introduced a permutation test that compares images, such as dose distributions from radiotherapy, while tackling the multiple comparisons problem. A test statistic Tmax was proposed that summarizes the differences between the images into a single value and a permutation procedure was employed to compute the adjusted p-value. We demonstrated the method in two retrospective studies: a prostate study that relates 3D dose distributions to failure, and an esophagus study that relates 2D surface dose distributions of the esophagus to acute esophagus toxicity. As a result, we were able to identify suspicious regions that are significantly associated with failure (prostate study) or toxicity (esophagus study). Permutation testing allows direct comparison of images from different patient categories and is a useful tool for data mining in radiotherapy. PMID:24365155

  10. Estimation of false discovery rate using sequential permutation p-values.

    PubMed

    Bancroft, Tim; Du, Chuanlong; Nettleton, Dan

    2013-03-01

    We consider the problem of testing each of m null hypotheses with a sequential permutation procedure in which the number of draws from the permutation distribution of each test statistic is a random variable. Each sequential permutation p-value has a null distribution that is nonuniform on a discrete support. We show how to use a collection of such p-values to estimate the number of true null hypotheses m0 among the m null hypotheses tested and how to estimate the false discovery rate (FDR) associated with p-value significance thresholds. We use real data analyses and simulation studies to evaluate and illustrate the performance of our proposed approach relative to standard, more computationally intensive strategies. We find that our sequential approach produces similar results with far less computational expense in a variety of scenarios.

  11. Communication Between RNA Folding Domains Revealed by Folding of Circularly Permuted Ribozymes

    SciTech Connect

    Lease,R.; Adilakshmi, T.; Heilman-Miller, S.; Woodson, S.

    2007-01-01

    To study the role of sequence and topology in RNA folding, we determined the kinetic folding pathways of two circularly permuted variants of the Tetrahymena group I ribozyme, using time-resolved hydroxyl radical footprinting. Circular permutation changes the distance between interacting residues in the primary sequence, without changing the native structure of the RNA. In the natural ribozyme, tertiary interactions in the P4-P6 domain form in 1 s, while interactions in the P3-P9 form in 1-3 min at 42 C. Permutation of the 5' end to G111 in the P4 helix allowed the stable P4-P6 domain to fold in 200 ms at 30 C, five times faster than in the wild-type RNA, while the other domains folded five times more slowly (5-8 min). By contrast, circular permutation of the 5' end to G303 in J8/7 decreased the folding rate of the P4-P6 domain. In this permuted RNA, regions joining P2, P3 and P4 were protected in 500 ms, while the P3-P9 domain was 60-80% folded within 30 s. RNase T1 digestion and FMN photocleavage showed that circular permutation of the RNA sequence alters the initial ensemble of secondary structures, thereby changing the tertiary folding pathways. Our results show that the natural 5'-to-3' order of the structural domains in group I ribozymes optimizes structural communication between tertiary domains and promotes self-assembly of the catalytic center.

  12. A Comparison of Multiscale Permutation Entropy Measures in On-Line Depth of Anesthesia Monitoring.

    PubMed

    Su, Cui; Liang, Zhenhu; Li, Xiaoli; Li, Duan; Li, Yongwang; Ursino, Mauro

    2016-01-01

    Multiscale permutation entropy (MSPE) is becoming an interesting tool to explore neurophysiological mechanisms in recent years. In this study, six MSPE measures were proposed for on-line depth of anesthesia (DoA) monitoring to quantify the anesthetic effect on the real-time EEG recordings. The performance of these measures in describing the transient characters of simulated neural populations and clinical anesthesia EEG were evaluated and compared. Six MSPE algorithms-derived from Shannon permutation entropy (SPE), Renyi permutation entropy (RPE) and Tsallis permutation entropy (TPE) combined with the decomposition procedures of coarse-graining (CG) method and moving average (MA) analysis-were studied. A thalamo-cortical neural mass model (TCNMM) was used to generate noise-free EEG under anesthesia to quantitatively assess the robustness of each MSPE measure against noise. Then, the clinical anesthesia EEG recordings from 20 patients were analyzed with these measures. To validate their effectiveness, the ability of six measures were compared in terms of tracking the dynamical changes in EEG data and the performance in state discrimination. The Pearson correlation coefficient (R) was used to assess the relationship among MSPE measures. CG-based MSPEs failed in on-line DoA monitoring at multiscale analysis. In on-line EEG analysis, the MA-based MSPE measures at 5 decomposed scales could track the transient changes of EEG recordings and statistically distinguish the awake state, unconsciousness and recovery of consciousness (RoC) state significantly. Compared to single-scale SPE and RPE, MSPEs had better anti-noise ability and MA-RPE at scale 5 performed best in this aspect. MA-TPE outperformed other measures with faster tracking speed of the loss of unconsciousness. MA-based multiscale permutation entropies have the potential for on-line anesthesia EEG analysis with its simple computation and sensitivity to drug effect changes. CG-based multiscale permutation

  13. Communication between RNA folding domains revealed by folding of circularly permuted ribozymes.

    PubMed

    Lease, Richard A; Adilakshmi, Tadepalli; Heilman-Miller, Susan; Woodson, Sarah A

    2007-10-12

    To study the role of sequence and topology in RNA folding, we determined the kinetic folding pathways of two circularly permuted variants of the Tetrahymena group I ribozyme, using time-resolved hydroxyl radical footprinting. Circular permutation changes the distance between interacting residues in the primary sequence, without changing the native structure of the RNA. In the natural ribozyme, tertiary interactions in the P4-P6 domain form in 1 s, while interactions in the P3-P9 form in 1-3 min at 42 degrees C. Permutation of the 5' end to G111 in the P4 helix allowed the stable P4-P6 domain to fold in 200 ms at 30 degrees C, five times faster than in the wild-type RNA, while the other domains folded five times more slowly (5-8 min). By contrast, circular permutation of the 5' end to G303 in J8/7 decreased the folding rate of the P4-P6 domain. In this permuted RNA, regions joining P2, P3 and P4 were protected in 500 ms, while the P3-P9 domain was 60-80% folded within 30 s. RNase T(1) digestion and FMN photocleavage showed that circular permutation of the RNA sequence alters the initial ensemble of secondary structures, thereby changing the tertiary folding pathways. Our results show that the natural 5'-to-3' order of the structural domains in group I ribozymes optimizes structural communication between tertiary domains and promotes self-assembly of the catalytic center.

  14. [A study of sleep stage classification based on permutation entropy for electroencephalogram].

    PubMed

    Li, Gu; Fan, Yingle; Pang, Quan

    2009-08-01

    This paper presents a new method for automatic sleep stage classification which is based on the EEG permutation entropy. The EEG permutation entropy has notable distinction in each stage of sleep and manifests the trend of regular transforming. So it can be used as features of sleep EEG in each stage. Nearest neighbor is employed as the pattern recognition method to classify the stages of sleep. Experiments are conducted on 750 sleep EEG samples and the mean identification rate can be up to 79.6%.

  15. Storage and computationally efficient permutations of factorized covariance and square-root information arrays

    NASA Technical Reports Server (NTRS)

    Muellerschoen, R. J.

    1988-01-01

    A unified method to permute vector stored Upper triangular Diagonal factorized covariance and vector stored upper triangular Square Root Information arrays is presented. The method involves cyclic permutation of the rows and columns of the arrays and retriangularization with fast (slow) Givens rotations (reflections). Minimal computation is performed, and a one dimensional scratch array is required. To make the method efficient for large arrays on a virtual memory machine, computations are arranged so as to avoid expensive paging faults. This method is potentially important for processing large volumes of radio metric data in the Deep Space Network.

  16. Women who doctor shop for prescription drugs.

    PubMed

    Worley, Julie; Thomas, Sandra P

    2014-04-01

    Doctor shopping is a term used to describe a form of diversion of prescription drugs when patients visit numerous prescribers to obtain controlled drugs for illicit use. Gender differences exist in regard to prescription drug abuse and methods of diversion. The purpose of this phenomenological study guided by the existential philosophy of Merleau-Ponty was to understand the lived experience of female doctor shoppers. Interviews were conducted with 14 women, which were recorded, transcribed, and analyzed. Included in the findings are figural aspects of the participants' experience of doctor shopping related to the existential grounds of world, time, body, and others. Four themes emerged from the data: (a) feeding the addiction, (b) networking with addicts, (c) playing the system, and (d) baiting the doctors. The findings suggest several measures that nurses can take to reduce the incidence of doctor shopping and to provide better care for female doctor shoppers.

  17. Consultation behaviour of doctor-shopping patients and factors that reduce shopping.

    PubMed

    Ohira, Yoshiyuki; Ikusaka, Masatomi; Noda, Kazutaka; Tsukamoto, Tomoko; Takada, Toshihiko; Miyahara, Masahito; Funakoshi, Hiraku; Basugi, Ayako; Keira, Katsunori; Uehara, Takanori

    2012-04-01

    To investigate the subsequent behaviour of doctor-shopping patients (defined as those attending multiple hospitals for the same complaint) who consulted our department and factors related to cessation of doctor shopping. Patients who presented without referral to the Department of General Medicine at Chiba University Hospital in Japan (our department) completed a questionnaire at their first visit. A follow-up questionnaire was also sent to them in order to assess doctor shopping after 3 months. Then items in the questionnaires were investigated for significant differences between patients who continued or stopped doctor shopping. Logistic regression analysis was performed with items showing a significant difference between patients who stopped doctor shopping and those who continued it, in order to identify independent determinants of the cessation of shopping. A total of 978 patients who presented spontaneously to our department consented to this study, and 929 patients (95.0%) completed questionnaires correctly. Among them, 203 patients (21.9%) were identified as doctor shoppers. The follow-up survey was completed correctly by 138 patients (68.0%). Among them, 25 patients (18.1%) were found to have continued doctor shopping, which was a significantly lower rate than before (P < 0.001). Logistic regression analysis selected the following factors as independent determinants of the cessation of doctor shopping: 'confirmation of the diagnosis' (odds ratio: 8.12, 95% confidence interval: 1.46-45.26), and 'satisfaction with consultation' (odds ratio: 2.07, 95% confidence interval: 1.42-3.01). Doctor shopping decreased significantly after patients consulted our department, with 'confirmation of the diagnosis' and 'satisfaction with consultation' being identified as contributing factors. © 2010 Blackwell Publishing Ltd.

  18. 10. Interior view of shop area showing grease pit ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Interior view of shop area showing grease pit - Fort Hood, World War II Temporary Buildings, Company Maintenance Shop & Arms Room, North of Park Avenue at Forty-ninth Street, Killeen, Bell County, TX

  19. 12. Interior detail of column base at shop area ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Interior detail of column base at shop area - Fort Hood, World War II Temporary Buildings, Company Maintenance Shop & Arms Room, North of Park Avenue at Forty-ninth Street, Killeen, Bell County, TX

  20. 11. Interior detail showing truss structure at shop area ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Interior detail showing truss structure at shop area - Fort Hood, World War II Temporary Buildings, Company Maintenance Shop & Arms Room, North of Park Avenue at Forty-ninth Street, Killeen, Bell County, TX

  1. 17. BIRD'S EYE VIEW OF FABRICATING SHOP FROM THE HOMESTEAD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. BIRD'S EYE VIEW OF FABRICATING SHOP FROM THE HOMESTEAD HIGH LEVEL BRIDGE. Jet Lowe, Photographer, 1989. - U.S. Steel Homestead Works, Auxiliary Buildings & Shops, Along Monongahela River, Homestead, Allegheny County, PA

  2. VIEW NORTHEASTCENTERBUILDING 110 CARPENTER SHOP (1908) RIGHTBUILDING 102 ELMER STREET ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW NORTHEAST-CENTER-BUILDING 110 CARPENTER SHOP (1908) RIGHT-BUILDING 102 ELMER STREET ROPE SHOP (1917) - John A. Roebling's Sons Company & American Steel & Wire Company, South Broad, Clark, Elmer, Mott & Hudson Streets, Trenton, Mercer County, NJ

  3. View of machine shops (buildings 17 & 19), east along ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of machine shops (buildings 17 & 19), east along Porter Avenue with quality assurance office (building 121) in foreground. - Naval Base Philadelphia-Philadelphia Naval Shipyard, Machine Shops, League Island, Philadelphia, Philadelphia County, PA

  4. 1. Oil House, Southern Pacific Railroad Carlin Shops, southwest facade, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Oil House, Southern Pacific Railroad Carlin Shops, southwest facade, view to northeast (135mm lens). - Southern Pacific Railroad, Carlin Shops, Oil House, Foot of Sixth Street, Carlin, Elko County, NV

  5. 4. Oil House, Southern Pacific Railroad Carlin Shops, southeast elevation, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Oil House, Southern Pacific Railroad Carlin Shops, southeast elevation, view to northwest (90mm lens). - Southern Pacific Railroad, Carlin Shops, Oil House, Foot of Sixth Street, Carlin, Elko County, NV

  6. 2. Oil House, Southern Pacific Railroad Carlin Shops, northwest elevation, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Oil House, Southern Pacific Railroad Carlin Shops, northwest elevation, view to southeast (135mm lens). - Southern Pacific Railroad, Carlin Shops, Oil House, Foot of Sixth Street, Carlin, Elko County, NV

  7. 57. VIEW OF SITE OF BLACKSMITH SHOPS ALONG CAREY STREET ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    57. VIEW OF SITE OF BLACKSMITH SHOPS ALONG CAREY STREET FOLLOWING DEMOLITION. - Baltimore & Ohio Railroad, Mount Clare Shops, South side of Pratt Street between Carey & Poppleton Streets, Baltimore, Independent City, MD

  8. INTERIOR VIEW OF MACHINE, METAL AND ELECTRIC SHOPS FROM THE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    INTERIOR VIEW OF MACHINE, METAL AND ELECTRIC SHOPS FROM THE ELECTRIC SHOP. RAILROAD TRACKS IN FLOOR. VIEW FROM THE WEST - Kekaha Sugar Company, Sugar Mill Building, 8315 Kekaha Road, Kekaha, Kauai County, HI

  9. 26. MOORSE DRILL CABINET AND FORK ART FABRICATED AT SHOP ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    26. MOORSE DRILL CABINET AND FORK ART FABRICATED AT SHOP (L TO R)- LOOKING SOUTHEAST. - W. A. Young & Sons Foundry & Machine Shop, On Water Street along Monongahela River, Rices Landing, Greene County, PA

  10. 33. GENERAL VIEW OF SHOPS COMPLEX LOOKING EAST, PAYMASTER'S OFFICE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    33. GENERAL VIEW OF SHOPS COMPLEX LOOKING EAST, PAYMASTER'S OFFICE IN FOREGROUND, LEFT; PUMPHOUSE, CENTER; SHOPS BUILDING TO RIGHT; SHEDS, FAR RIGHT - Soudan Iron Mine, Tower-Soudan State Park, Tower, St. Louis County, MN

  11. 1. SOUTHWEST FRONT AND SOUTHEAST SIDE OF BLACKSMITH SHOP REMAINS, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. SOUTHWEST FRONT AND SOUTHEAST SIDE OF BLACKSMITH SHOP REMAINS, TENANT HOUSE IN BACKGROUND - Mount Etna Iron Works, Blacksmith Shop, East of U.S. Route 22 on T.R. 463, Williamsburg, Blair County, PA

  12. Oblique view of blacksmith shop, showing south and east (front) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Oblique view of blacksmith shop, showing south and east (front) elevations; camera facing northwest - Lemmon-Anderson-Hixson Ranch, Blacksmith Shop, 11220 North Virginia Street, Reno, Washoe County, NV

  13. Contextual view of blacksmith shop, showing summer kitchen uphill at ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Contextual view of blacksmith shop, showing summer kitchen uphill at left; camera facing northwest - Lemmon-Anderson-Hixson Ranch, Blacksmith Shop, 11220 North Virginia Street, Reno, Washoe County, NV

  14. Oblique view of blacksmith shop, showing north and west (rear) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Oblique view of blacksmith shop, showing north and west (rear) elevations; camera facing southeast - Lemmon-Anderson-Hixson Ranch, Blacksmith Shop, 11220 North Virginia Street, Reno, Washoe County, NV

  15. INTERIOR OF CENTRAL ROOM OF PAINT SHOP PORTION OF BUILDING, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    INTERIOR OF CENTRAL ROOM OF PAINT SHOP PORTION OF BUILDING, FACING SOUTHEAST - Vancouver Barracks, Paint Shop and Central Heating Plant, East Fifth Street southeast of McLoughlin Road, Vancouver, Clark County, WA

  16. 9. Interior view looking E on second floor Paint Shop. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. Interior view looking E on second floor Paint Shop. - Central of Georgia Railway, Savannah Repair Shops & Terminal Facilities, Paint & Coach Barn, Bounded by West Broad, Jones, West Boundary & Hull Streets, Savannah, Chatham County, GA

  17. 10. Boiler Works, Machine Shop and Pattern Storage, to right; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Boiler Works, Machine Shop and Pattern Storage, to right; Hose House and Paint Storage, to left; Headhouses, left center; Pipe, Paint, and Electrical Shop center. - Thames Tow Boat Company, Foot of Farnsworth Street, New London, New London County, CT

  18. INTERIOR OF EASTERN ROOM OF PAINT SHOP PORTION OF BUILDING, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    INTERIOR OF EASTERN ROOM OF PAINT SHOP PORTION OF BUILDING, FACING SOUTHWEST - Vancouver Barracks, Paint Shop and Central Heating Plant, East Fifth Street southeast of McLoughlin Road, Vancouver, Clark County, WA

  19. Looking southwest at dualtrack transfer table, with Machine Shop (Bldg. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Looking southwest at dual-track transfer table, with Machine Shop (Bldg. 163) in background - Atchison, Topeka, Santa Fe Railroad, Albuquerque Shops, 908 Second Street, Southwest, Albuquerque, Bernalillo County, NM

  20. First roundhouse and shops. Photograph taken between 1874 and 1878, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    First roundhouse and shops. Photograph taken between 1874 and 1878, at the same time as IL-8-78. Looking north - Chicago, Burlington & Quincy Railroad, Roundhouse & Shops, Broadway & Spring Streets, Aurora, Kane County, IL

  1. 21. General view inside boiler shop section of roundhouse. View ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. General view inside boiler shop section of roundhouse. View to west. - Duluth & Iron Range Rail Road Company Shops, Roundhouse, Southwest of downtown Two Harbors, northwest of Agate Bay, Two Harbors, Lake County, MN

  2. North side and west end. Machine shop section of roundhouse ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    North side and west end. Machine shop section of roundhouse (MN-99-A) in background. View to southeast - Duluth & Iron Range Rail Road Company Shops, Foundry, Southwest of downtown Two Harbors, northwest of Agate Bay, Two Harbors, Lake County, MN

  3. 22. General view inside air brake shop section of roundhouse. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. General view inside air brake shop section of roundhouse. View to west. - Duluth & Iron Range Rail Road Company Shops, Roundhouse, Southwest of downtown Two Harbors, northwest of Agate Bay, Two Harbors, Lake County, MN

  4. 20. General view inside blacksmith shop section of roundhouse. View ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. General view inside blacksmith shop section of roundhouse. View to northwest. - Duluth & Iron Range Rail Road Company Shops, Roundhouse, Southwest of downtown Two Harbors, northwest of Agate Bay, Two Harbors, Lake County, MN

  5. 9. General view inside machine shop section of roundhouse. View ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. General view inside machine shop section of roundhouse. View to north. - Duluth & Iron Range Rail Road Company Shops, Roundhouse, Southwest of downtown Two Harbors, northwest of Agate Bay, Two Harbors, Lake County, MN

  6. 10. Detail of crane over main floor inside machine shop ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Detail of crane over main floor inside machine shop section of roundhouse. View to southwest. - Duluth & Iron Range Rail Road Company Shops, Roundhouse, Southwest of downtown Two Harbors, northwest of Agate Bay, Two Harbors, Lake County, MN

  7. 1. EXTERIOR OF CIVIL ENGINEERING MAINTENANCE SHOP, BUILDING 103, LOOKING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. EXTERIOR OF CIVIL ENGINEERING MAINTENANCE SHOP, BUILDING 103, LOOKING NORTH. - Mill Valley Air Force Station, Civil Engineering Maintenance Shop, East Ridgecrest Boulevard, Mount Tamalpais, Mill Valley, Marin County, CA

  8. View looking southeast to the Erecting Shop on the corner ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View looking southeast to the Erecting Shop on the corner of Spruce Street and Market Street (similar to HAER No. NJ-3-A-2) - Rogers Locomotive & Machine Works, Erecting Shop, Spruce & Market Streets, Paterson, Passaic County, NJ

  9. 7. Interior view looking N in Coach Shop. Central ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Interior view looking N in Coach Shop. - Central of Georgia Railway, Savannah Repair Shops & Terminal Facilities, Paint & Coach Barn, Bounded by West Broad, Jones, West Boundary & Hull Streets, Savannah, Chatham County, GA

  10. West end view, "Boat Shop" open doorway, Facility 7 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    West end view, "Boat Shop" - open doorway, Facility 7 connected on the left, view facing east-southeast - U.S. Naval Base, Pearl Harbor, Boat Shop, Seventh Street near Avenue E, Pearl City, Honolulu County, HI

  11. 56. VIEW OF SITE OF BLACKSMITH SHOPS ALONG CAREY STREET ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    56. VIEW OF SITE OF BLACKSMITH SHOPS ALONG CAREY STREET FOLLOWING DEMOLITION. - Baltimore & Ohio Railroad, Mount Clare Shops, South side of Pratt Street between Carey & Poppleton Streets, Baltimore, Independent City, MD

  12. Rod shop, roof and truss detail showing older pink roof ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Rod shop, roof and truss detail showing older pink roof truss, newer pratt truss, and longitudinal, truss for overhead traveling crane - Chicago, Burlington & Quincy Railroad, Roundhouse & Shops, Broadway & Spring Streets, Aurora, Kane County, IL

  13. ELEVATION LOOKING WEST OF PRINCIPLE FACADE OF SIGN SHOP ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    ELEVATION LOOKING WEST OF PRINCIPLE FACADE OF SIGN SHOP - New York State Soldiers & Sailors Home, Sign Shop, Department of Veterans Affairs Medical Center, 76 Veterans Avenue, Bath, Steuben County, NY

  14. Interior view of the Sheet Metal Shop showing the roof ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior view of the Sheet Metal Shop showing the roof trusses and corrugated metal roof covering, view facing northwest - Kahului Cannery, Plant No. 28, Boiler House, Sheet Metal and Electrical Shops, 120 Kane Street, Kahului, Maui County, HI

  15. 14. AERIAL VIEW OF ENGINE DISPLAY INSIDE PASSENGER CAR SHOP ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. AERIAL VIEW OF ENGINE DISPLAY INSIDE PASSENGER CAR SHOP (NOW A TRANSPORTATION MUSEUM) - Baltimore & Ohio Railroad, Mount Clare Passenger Car Shop, Southwest corner of Pratt & Poppleton Streets, Baltimore, Independent City, MD

  16. 3. GENERAL VIEW OF PASSENGER CAR SHOP; RAILROAD TRACKS IN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. GENERAL VIEW OF PASSENGER CAR SHOP; RAILROAD TRACKS IN FOREGROUND - Baltimore & Ohio Railroad, Mount Clare Passenger Car Shop, Southwest corner of Pratt & Poppleton Streets, Baltimore, Independent City, MD

  17. 11. VIEW OF CIRCULAR CAR SHOP OVER TOPS OF BOX ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. VIEW OF CIRCULAR CAR SHOP OVER TOPS OF BOX CARS LOOKING NORTHEAST. - Baltimore & Ohio Railroad, Mount Clare Shops, South side of Pratt Street between Carey & Poppleton Streets, Baltimore, Independent City, MD

  18. Steam Engine for Shop, lineshaft, detail of crosshead, rod and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Steam Engine for Shop, lineshaft, detail of crosshead, rod and flywheel - East Broad Top Railroad & Coal Company, Machine Shop, State Route 994, West of U.S. Route 522, Rockhill Furnace, Huntingdon County, PA

  19. 8. MACHINE SHOP, INTERIOR, LOOKING AT ROOF TRUSS SYSTEM. NOTE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. MACHINE SHOP, INTERIOR, LOOKING AT ROOF TRUSS SYSTEM. NOTE DECORATIVE WOOD COLUMN AT LOWER LEFT. - Baltimore & Ohio Railroad, Keyser Machine Shop, State Route 46 Northwest of Spring Street, Keyser, Mineral County, WV

  20. 11. Interior view, second floor, tin shop area looking southwest, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Interior view, second floor, tin shop area looking southwest, showing laminated plank arched roof trusses. - Larrabee & Hingston Company, Main Shop Building, 19 Howley Street, Peabody, Essex County, MA

  1. Western view of coupling blank building, with general machine shop ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Western view of coupling blank building, with general machine shop and pattern shop on left. - U.S. Steel National Tube Works, Auxiliary Buildings, Along Monongahela River, McKeesport, Allegheny County, PA

  2. Boiler & Tank Shop, north elevation. The Pittsburgh, Chartiers & ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Boiler & Tank Shop, north elevation. The Pittsburgh, Chartiers & Youghiogheny Railway (PC&Y) bridge is at far right. - Pittsburgh & Lake Erie Railroad, Locomotive Repair Shops, River Road at Chartiers Avenue, McKees Rocks, Allegheny County, PA

  3. Doctor and pharmacy shopping for controlled substances.

    PubMed

    Peirce, Gretchen L; Smith, Michael J; Abate, Marie A; Halverson, Joel

    2012-06-01

    Prescription drug abuse is a major health concern nationwide, with West Virginia having one of the highest prescription drug death rates in the United States. Studies are lacking that compare living subjects with persons who died from drug overdose for evidence of doctor and pharmacy shopping for controlled substances. The study objectives were to compare deceased and living subjects in West Virginia for evidence of prior doctor and pharmacy shopping for controlled substances and to identify factors associated with drug-related death. A secondary data study was conducted using controlled substance, Schedule II-IV, prescription data from the West Virginia Controlled Substance Monitoring Program and drug-related death data compiled by the Forensic Drug Database between July 2005 and December 2007. A case-control design compared deceased subjects 18 years and older whose death was drug related with living subjects for prior doctor and pharmacy shopping. Logistic regression identified factors related to the odds of drug-related death. A significantly greater proportion of deceased subjects were doctor shoppers (25.21% vs. 3.58%) and pharmacy shoppers (17.48% vs. 1.30%) than living subjects. Approximately 20.23% of doctor shoppers were also pharmacy shoppers, and 55.60% of pharmacy shoppers were doctor shoppers. Younger age, greater number of prescriptions dispensed, exposure to opioids and benzodiazepines, and doctor and pharmacy shopping were factors with greater odds of drug-related death. Doctor and pharmacy shopping involving controlled substances were identified, and shopping behavior was associated with drug-related death. Prescription monitoring programs may be useful in identifying potential shoppers at the point of care.

  4. Quality assurance in small plating shops

    SciTech Connect

    McNabb, W.J. )

    1993-10-01

    The potential for electroless nickel coatings in oilfield and petrochemical applications is quite high. The greatest obstacle to their use has been a reputation for poor quality due to a lack of quality control in many plating shops. To overcome this, electroless nickel shops should not only have a quality control program in their operation, but must also document its use and success. This article describes how a plating shoe can develop the necessary procedures, manuals, and paperwork trail to offer quality assurance and to satisfy customers.

  5. View north of tube bending shop in boilermakers department located ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View north of tube bending shop in boilermakers department located in southeast corner of the structural shop building (building 57). The computer controlled tube bender can be programmed to bend boiler tubing to nearly any required configuration - Naval Base Philadelphia-Philadelphia Naval Shipyard, Structure Shop, League Island, Philadelphia, Philadelphia County, PA

  6. Machine Shop (Bldg. 163) north bay, east end interior looking ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Machine Shop (Bldg. 163) north bay, east end interior looking northeast. Note the 250-ton Shaw bridge crane on the upper rails and two smaller P&H bridge cranes on the lower rails. Three cranes shared the lower rails - Atchison, Topeka, Santa Fe Railroad, Albuquerque Shops, Machine Shop, 908 Second Street, Southwest, Albuquerque, Bernalillo County, NM

  7. Internet Shopping Behavior of College of Education Students

    ERIC Educational Resources Information Center

    Kiyici, Mubin

    2012-01-01

    Internet is an important facilitator for human and humans use this medium almost every phase. As a shopping medium, internet attract human so attract researcher. Younger people can adapt newer technologies so they can adapt internet as shopping tool. In this research it is tried to define college of education students' online shopping behavior and…

  8. 14. BLACKSMITH SHOP IN THE CENTER OF PHOTOGRAPH. TO THE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. BLACKSMITH SHOP IN THE CENTER OF PHOTOGRAPH. TO THE LEFT IS MACHINE SHOP No. 1, AND TO THE RIGHT IS THE CHIPPING YARD. THE RUINS IN THE FOREGROUND IS THE FORMER ELECTRIC DEPARTMENT. Jet Lowe, Photographer, 1989. - U.S. Steel Homestead Works, Auxiliary Buildings & Shops, Along Monongahela River, Homestead, Allegheny County, PA

  9. 1. Photocopy of photograph of Blacksmith Shop. Original on file ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Photocopy of photograph of Blacksmith Shop. Original on file with the Payette National Forest, Supervisor's Office, McCall, Idaho. BLACKSMITH SHOP CA. 1935, FACING NORTH. BARN IS IN BACKGROUND. - Hornet Ranger Station, Blacksmith Shop, Forest Service Road No. 50002, Council, Adams County, ID

  10. 61. August 1974. PAINT SHOP, VIEW LOOKING EAST. THE WINDOW ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    61. August 1974. PAINT SHOP, VIEW LOOKING EAST. THE WINDOW IS IN THE CENTER OF A SLIDING DOOR THAT OPENS ONTO THE PORCH AT THE EAST END OF THE ORIGINAL 1883 SHOP. THE DOOR WAS USED FOR HAULING THE WAGONS UP TO THE PAINT SHOP. - Gruber Wagon Works, Pennsylvania Route 183 & State Hill Road at Red Bridge Park, Bernville, Berks County, PA

  11. Standardized Curriculum for Machine Tool Operation/Machine Shop.

    ERIC Educational Resources Information Center

    Mississippi State Dept. of Education, Jackson. Office of Vocational, Technical and Adult Education.

    Standardized vocational education course titles and core contents for two courses in Mississippi are provided: machine tool operation/machine shop I and II. The first course contains the following units: (1) orientation; (2) shop safety; (3) shop math; (4) measuring tools and instruments; (5) hand and bench tools; (6) blueprint reading; (7)…

  12. 17. Interior oblique view, original Cooper's Shop, Engine Stores Building, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. Interior oblique view, original Cooper's Shop, Engine Stores Building, Southern Pacific Railroad Carlin Shops, view to southeast (90mm lens). Note the original window and sealed doorway. - Southern Pacific Railroad, Carlin Shops, Engine Stores Building, Foot of Sixth Street, Carlin, Elko County, NV

  13. 7. South wall of blacksmith shop section of roundhouse at ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. South wall of blacksmith shop section of roundhouse at left. West wall and south end wall of machine shop section of roundhouse at right. View to northeast. - Duluth & Iron Range Rail Road Company Shops, Roundhouse, Southwest of downtown Two Harbors, northwest of Agate Bay, Two Harbors, Lake County, MN

  14. Shopping Centers: Their Development and Impact on a Community.

    ERIC Educational Resources Information Center

    Berezowski, P. E.; And Others

    Presenting extensive background material on the development of shopping centers, this paper includes elementary and junior high school outdoor education activities centering upon shopping center studies. Background material includes analysis of the following: shopping center types (architecture, regional location, etc); land use (guidelines for…

  15. 1. THREEQUARTER VIEW OF MECHANICAL SHOP, SHOWING EAST AND NORTH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. THREE-QUARTER VIEW OF MECHANICAL SHOP, SHOWING EAST AND NORTH SIDES; LOOKING SOUTHWEST; POWER PLANT IN BACKGROUND AT RIGHT; SAWTOOTH MONITORS ON BEEF KILL (BUILDING 149) VISIBLE ABOVE SHOP BUILDING AT CENTER OF PHOTO - Rath Packing Company, Mechanical Shop, Sycamore Street between Elm & Eighteenth Streets, Waterloo, Black Hawk County, IA

  16. Standardized Curriculum for Machine Tool Operation/Machine Shop.

    ERIC Educational Resources Information Center

    Mississippi State Dept. of Education, Jackson. Office of Vocational, Technical and Adult Education.

    Standardized vocational education course titles and core contents for two courses in Mississippi are provided: machine tool operation/machine shop I and II. The first course contains the following units: (1) orientation; (2) shop safety; (3) shop math; (4) measuring tools and instruments; (5) hand and bench tools; (6) blueprint reading; (7)…

  17. Teaching Spanish on Weekends and in Shopping Centers.

    ERIC Educational Resources Information Center

    Baker, Clayton; East, James R.

    1982-01-01

    Describes two programs for adult learners, Weekend College and Learn and Shop. Weekend College offered credit courses on Saturdays and Sundays; Learn and Shop used employee training rooms at five major shopping centers. Statistics on both programs are given as well as a description of the Spanish Department offerings and reactions. (AMH)

  18. VIEW NORTHFOREGROUNDBUILDING 121 TEMPERING SHOP NO. 2 (1944) LEFT (LARGE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW NORTH-FOREGROUND-BUILDING 121 TEMPERING SHOP NO. 2 (1944) LEFT (LARGE WINDOW-BUILDING 54 FLAT SHOP 3A (1954) CENTER TOP-BUILDING 58-TEMPERING SHOP NO. 1 (c.1910) RIGHT-BUILDING 119-WIRE STORAGE (c.1945) - John A. Roebling's Sons Company & American Steel & Wire Company, South Broad, Clark, Elmer, Mott & Hudson Streets, Trenton, Mercer County, NJ

  19. VIEW OF TURNTABLE, WITH CAR MACHINE SHOP AND PLANING MILL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF TURNTABLE, WITH CAR MACHINE SHOP AND PLANING MILL IN THE BACKGROUND AND ERECTING/MACHINE SHOP AT RIGHT, LOOKING EAST. ATSF 5021 2-10-4 STEAM LOCOMOTIVE IS ON TURNTABLE. - Southern Pacific, Sacramento Shops, 111 I Street, Sacramento, Sacramento County, CA

  20. 8. VIEW OF THE MACHINE SHOP. BY 1966, THE MACHINE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. VIEW OF THE MACHINE SHOP. BY 1966, THE MACHINE SHOP HANDLED PRIMARILY STAINLESS STEEL COMPONENTS, WHICH WERE SENT TO THE MACHINE SHOP TO BE FORMED INTO THEIR FINAL SHAPES. (7/24/70) - Rocky Flats Plant, General Manufacturing, Support, Records-Central Computing, Southern portion of Plant, Golden, Jefferson County, CO

  1. Shopping Centers: Their Development and Impact on a Community.

    ERIC Educational Resources Information Center

    Berezowski, P. E.; And Others

    Presenting extensive background material on the development of shopping centers, this paper includes elementary and junior high school outdoor education activities centering upon shopping center studies. Background material includes analysis of the following: shopping center types (architecture, regional location, etc); land use (guidelines for…

  2. PERSPECTIVE VIEW OF THE Erection Shop FROM THE northeast. The ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PERSPECTIVE VIEW OF THE Erection Shop FROM THE northeast. The Power House can be seen in shadow on the left, and the Boiler & Tank Shop is to the far right. - Pittsburgh & Lake Erie Railroad, Locomotive Repair Shops, River Road at Chartiers Avenue, McKees Rocks, Allegheny County, PA

  3. Permutation and parametric tests for effect sizes in voxel-based morphometry of grey matter volume in brain structural MRI

    PubMed Central

    Dickie, David A.; Mikhael, Shadia; Job, Dominic E.; Wardlaw, Joanna M.; Laidlaw, David H.; Bastin, Mark E.

    2015-01-01

    Permutation testing has been widely implemented in voxel-based morphometry (VBM) tools. However, this type of non-parametric inference has yet to be thoroughly compared with traditional parametric inference in VBM studies of brain structure. Here we compare both types of inference and investigate what influence the number of permutations in permutation testing has on results in an exemplar study of how grey matter proportion changes with age in a group of working age adults. High resolution T1-weighted volume scans were acquired from 80 healthy adults aged 25–64 years. Using a validated VBM procedure and voxel-based permutation testing for Pearson product-moment coefficient, the effect sizes of changes in grey matter proportion with age were assessed using traditional parametric and permutation testing inference with 100, 500, 1000, 5000, 10000 and 20000 permutations. The statistical significance was set at P < 0.05 and false discovery rate (FDR) used to correct for multiple comparisons. Clusters of voxels with statistically significant (PFDR < 0.05) declines in grey matter proportion with age identified with permutation testing inference (N ≈ 6000) were approximately twice the size of those identified with parametric inference (N = 3221 voxels). Permutation testing with 10000 (N = 6251 voxels) and 20000 (N = 6233 voxels) permutations produced clusters that were generally consistent with each other. However, with ≥ 1000 permutations there were approximately 20% more statistically significant voxels (N = 7117 voxels) than with 10000 permutations. Permutation testing inference may provide a more sensitive method than traditional parametric inference for identifying age-related differences in grey matter proportion. Based on the results reported here, at least 10000 permutations should be used in future univariate VBM studies investigating age related changes in grey matter to avoid potential false findings. Additional studies using permutation testing in large

  4. Permutation and parametric tests for effect sizes in voxel-based morphometry of gray matter volume in brain structural MRI.

    PubMed

    Dickie, David A; Mikhael, Shadia; Job, Dominic E; Wardlaw, Joanna M; Laidlaw, David H; Bastin, Mark E

    2015-12-01

    Permutation testing has been widely implemented in voxel-based morphometry (VBM) tools. However, this type of non-parametric inference has yet to be thoroughly compared with traditional parametric inference in VBM studies of brain structure. Here we compare both types of inference and investigate what influence the number of permutations in permutation testing has on results in an exemplar study of how gray matter proportion changes with age in a group of working age adults. High resolution T1-weighted volume scans were acquired from 80 healthy adults aged 25-64years. Using a validated VBM procedure and voxel-based permutation testing for Pearson product-moment coefficient, the effect sizes of changes in gray matter proportion with age were assessed using traditional parametric and permutation testing inference with 100, 500, 1000, 5000, 10000 and 20000 permutations. The statistical significance was set at P<0.05 and false discovery rate (FDR) was used to correct for multiple comparisons. Clusters of voxels with statistically significant (PFDR<0.05) declines in gray matter proportion with age identified with permutation testing inference (N≈6000) were approximately twice the size of those identified with parametric inference (N=3221voxels). Permutation testing with 10000 (N=6251voxels) and 20000 (N=6233voxels) permutations produced clusters that were generally consistent with each other. However, with 1000 permutations there were approximately 20% more statistically significant voxels (N=7117voxels) than with ≥10000 permutations. Permutation testing inference may provide a more sensitive method than traditional parametric inference for identifying age-related differences in gray matter proportion. Based on the results reported here, at least 10000 permutations should be used in future univariate VBM studies investigating age related changes in gray matter to avoid potential false findings. Additional studies using permutation testing in large imaging databanks

  5. An improved permutation-diffusion type image cipher with a chaotic orbit perturbing mechanism.

    PubMed

    Chen, Jun-xin; Zhu, Zhi-liang; Fu, Chong; Yu, Hai

    2013-11-18

    During the past decades, chaos-based permutation-diffusion type image cipher has been widely investigated to meet the increasing demand for real-time secure image transmission over public networks. However, the existing researches almost exclusively focus on the improvements of the permutation and diffusion methods independently, without consideration of cooperation between the two processes. In this paper, an improved permutation-diffusion type image cipher with a chaotic orbit perturbing mechanism is proposed. In the permutation stage, pixels in the plain image are shuffled with a pixel-swapping mechanism, and the pseudorandom locations are generated by chaotic logistic map iteration. Furthermore, a plain pixel related chaotic orbit perturbing mechanism is introduced. As a result, a tiny change in plain image will be spread out during the confusion process, and hence an effective diffusion effect is introduced. By using a reverse direction diffusion method, the introduced diffusion effect will be further diffused to the whole cipher image within one overall encryption round. Simulation results and extensive cryptanalysis justify that the proposed scheme has a satisfactory security with a low computational complexity, which renders it a good candidate for real-time secure image storage and distribution applications.

  6. A studentized permutation test for three-arm trials in the 'gold standard' design.

    PubMed

    Mütze, Tobias; Konietschke, Frank; Munk, Axel; Friede, Tim

    2017-03-15

    The 'gold standard' design for three-arm trials refers to trials with an active control and a placebo control in addition to the experimental treatment group. This trial design is recommended when being ethically justifiable and it allows the simultaneous comparison of experimental treatment, active control, and placebo. Parametric testing methods have been studied plentifully over the past years. However, these methods often tend to be liberal or conservative when distributional assumptions are not met particularly with small sample sizes. In this article, we introduce a studentized permutation test for testing non-inferiority and superiority of the experimental treatment compared with the active control in three-arm trials in the 'gold standard' design. The performance of the studentized permutation test for finite sample sizes is assessed in a Monte Carlo simulation study under various parameter constellations. Emphasis is put on whether the studentized permutation test meets the target significance level. For comparison purposes, commonly used Wald-type tests, which do not make any distributional assumptions, are included in the simulation study. The simulation study shows that the presented studentized permutation test for assessing non-inferiority in three-arm trials in the 'gold standard' design outperforms its competitors, for instance the test based on a quasi-Poisson model, for count data. The methods discussed in this paper are implemented in the R package ThreeArmedTrials which is available on the comprehensive R archive network (CRAN). Copyright © 2016 John Wiley & Sons, Ltd.

  7. Levels of Conceptual Development in Melodic Permutation Concepts Based on Piaget's Theory

    ERIC Educational Resources Information Center

    Larn, Ronald L.

    1973-01-01

    Article considered different ways in which subjects at different age levels solved a musical task involving melodic permutation. The differences in responses to the musical task between age groups were judged to be compatible with Piaget's theory of cognitive development. (Author/RK)

  8. Heuristic Implementation of Dynamic Programming for Matrix Permutation Problems in Combinatorial Data Analysis

    ERIC Educational Resources Information Center

    Brusco, Michael J.; Kohn, Hans-Friedrich; Stahl, Stephanie

    2008-01-01

    Dynamic programming methods for matrix permutation problems in combinatorial data analysis can produce globally-optimal solutions for matrices up to size 30x30, but are computationally infeasible for larger matrices because of enormous computer memory requirements. Branch-and-bound methods also guarantee globally-optimal solutions, but computation…

  9. A note on permutation tests of significance for multiple regression coefficients.

    PubMed

    Long, Michael A; Berry, Kenneth J; Mielke, Paul W

    2007-04-01

    In the vast majority of psychological research utilizing multiple regression analysis, asymptotic probability values are reported. This paper demonstrates that asymptotic estimates of standard errors provided by multiple regression are not always accurate. A resampling permutation procedure is used to estimate the standard errors. In some cases the results differ substantially from the traditional least squares regression estimates.

  10. Circular permutation of the starch-binding domain: inversion of ligand selectivity with increased affinity.

    PubMed

    Stephen, Preyesh; Tseng, Kai-Li; Liu, Yu-Nan; Lyu, Ping-Chiang

    2012-03-07

    Proteins containing starch-binding domains (SBDs) are used in a variety of scientific and technological applications. A circularly permutated SBD (CP90) with improved affinity and selectivity toward longer-chain carbohydrates was synthesized, suggesting that a new starch-binding protein may be developed for specific scientific and industrial applications.

  11. Suppressing Permutations or Rigid Planar Rotations: A Remedy against Nonoptimal Varimax Rotations.

    ERIC Educational Resources Information Center

    Berge, Jos M. F. ten

    1995-01-01

    In Varimax rotation, permutations and reflections can give rise to the phenomenon that certain pairs of columns are consistently skipped in the iterative process, causing Varimax to terminate at a nonstationary point. This skipping phenomenon is demonstrated, and how to prevent it is described. (SLD)

  12. EPEPT: a web service for enhanced P-value estimation in permutation tests.

    PubMed

    Knijnenburg, Theo A; Lin, Jake; Rovira, Hector; Boyle, John; Shmulevich, Ilya

    2011-10-24

    In computational biology, permutation tests have become a widely used tool to assess the statistical significance of an event under investigation. However, the common way of computing the P-value, which expresses the statistical significance, requires a very large number of permutations when small (and thus interesting) P-values are to be accurately estimated. This is computationally expensive and often infeasible. Recently, we proposed an alternative estimator, which requires far fewer permutations compared to the standard empirical approach while still reliably estimating small P-values. The proposed P-value estimator has been enriched with additional functionalities and is made available to the general community through a public website and web service, called EPEPT. This means that the EPEPT routines can be accessed not only via a website, but also programmatically using any programming language that can interact with the web. Examples of web service clients in multiple programming languages can be downloaded. Additionally, EPEPT accepts data of various common experiment types used in computational biology. For these experiment types EPEPT first computes the permutation values and then performs the P-value estimation. Finally, the source code of EPEPT can be downloaded. Different types of users, such as biologists, bioinformaticians and software engineers, can use the method in an appropriate and simple way.

  13. EPEPT: A web service for enhanced P-value estimation in permutation tests

    PubMed Central

    2011-01-01

    Background In computational biology, permutation tests have become a widely used tool to assess the statistical significance of an event under investigation. However, the common way of computing the P-value, which expresses the statistical significance, requires a very large number of permutations when small (and thus interesting) P-values are to be accurately estimated. This is computationally expensive and often infeasible. Recently, we proposed an alternative estimator, which requires far fewer permutations compared to the standard empirical approach while still reliably estimating small P-values [1]. Results The proposed P-value estimator has been enriched with additional functionalities and is made available to the general community through a public website and web service, called EPEPT. This means that the EPEPT routines can be accessed not only via a website, but also programmatically using any programming language that can interact with the web. Examples of web service clients in multiple programming languages can be downloaded. Additionally, EPEPT accepts data of various common experiment types used in computational biology. For these experiment types EPEPT first computes the permutation values and then performs the P-value estimation. Finally, the source code of EPEPT can be downloaded. Conclusions Different types of users, such as biologists, bioinformaticians and software engineers, can use the method in an appropriate and simple way. Availability http://informatics.systemsbiology.net/EPEPT/ PMID:22024252

  14. Educational Facilities Thesaurus. Permuted Descriptor List, 1981. Report Studies...S.81.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Paris (France). Div. of Educational Policy and Planning.

    Some 2,500 descriptors dealing with the planning and design of educational buildings and equipment are included in this permuted index which was developed by the architects of the United Nations Educational, Scientific, and Cultural Organization's (Unesco's) Educational Facilities Section, the Unesco Regional Offices Educational Facilities units,…

  15. Explicit Symplectic-like Integrators with Midpoint Permutations for Spinning Compact Binaries

    NASA Astrophysics Data System (ADS)

    Luo, Junjie; Wu, Xin; Huang, Guoqing; Liu, Fuyao

    2017-01-01

    We refine the recently developed fourth-order extended phase space explicit symplectic-like methods for inseparable Hamiltonians using Yoshida’s triple product combined with a midpoint permuted map. The midpoint between the original variables and their corresponding extended variables at every integration step is readjusted as the initial values of the original variables and their corresponding extended ones at the next step integration. The triple-product construction is apparently superior to the composition of two triple products in computational efficiency. Above all, the new midpoint permutations are more effective in restraining the equality of the original variables and their corresponding extended ones at each integration step than the existing sequent permutations of momenta and coordinates. As a result, our new construction shares the benefit of implicit symplectic integrators in the conservation of the second post-Newtonian Hamiltonian of spinning compact binaries. Especially for the chaotic case, it can work well, but the existing sequent permuted algorithm cannot. When dissipative effects from the gravitational radiation reaction are included, the new symplectic-like method has a secular drift in the energy error of the dissipative system for the orbits that are regular in the absence of radiation, as an implicit symplectic integrator does. In spite of this, it is superior to the same-order implicit symplectic integrator in accuracy and efficiency. The new method is particularly useful in discussing the long-term evolution of inseparable Hamiltonian problems.

  16. The coupling analysis between stock market indices based on permutation measures

    NASA Astrophysics Data System (ADS)

    Shi, Wenbin; Shang, Pengjian; Xia, Jianan; Yeh, Chien-Hung

    2016-04-01

    Many information-theoretic methods have been proposed for analyzing the coupling dependence between time series. And it is significant to quantify the correlation relationship between financial sequences since the financial market is a complex evolved dynamic system. Recently, we developed a new permutation-based entropy, called cross-permutation entropy (CPE), to detect the coupling structures between two synchronous time series. In this paper, we extend the CPE method to weighted cross-permutation entropy (WCPE), to address some of CPE's limitations, mainly its inability to differentiate between distinct patterns of a certain motif and the sensitivity of patterns close to the noise floor. It shows more stable and reliable results than CPE does when applied it to spiky data and AR(1) processes. Besides, we adapt the CPE method to infer the complexity of short-length time series by freely changing the time delay, and test it with Gaussian random series and random walks. The modified method shows the advantages in reducing deviations of entropy estimation compared with the conventional one. Finally, the weighted cross-permutation entropy of eight important stock indices from the world financial markets is investigated, and some useful and interesting empirical results are obtained.

  17. Heuristic Implementation of Dynamic Programming for Matrix Permutation Problems in Combinatorial Data Analysis

    ERIC Educational Resources Information Center

    Brusco, Michael J.; Kohn, Hans-Friedrich; Stahl, Stephanie

    2008-01-01

    Dynamic programming methods for matrix permutation problems in combinatorial data analysis can produce globally-optimal solutions for matrices up to size 30x30, but are computationally infeasible for larger matrices because of enormous computer memory requirements. Branch-and-bound methods also guarantee globally-optimal solutions, but computation…

  18. Performance Support on the Shop Floor.

    ERIC Educational Resources Information Center

    Kasvi, Jyrki J. J.; Vartiainen, Matti

    2000-01-01

    Discussion of performance support on the shop floor highlights four support systems for assembly lines that incorporate personal computer workstations in local area networks and use multimedia documents. Considers new customer-focused production paradigms; organizational learning; knowledge development; and electronic performance support systems…

  19. Organizational Learning in Shop Floor Level

    ERIC Educational Resources Information Center

    Cheung, Che Keung; Geng, Shuang; Chuah, Kong Bieng; Chau, Yiu Chung; Kwong, Kar Fai

    2016-01-01

    Purpose: This paper aims to present the result of the pilot run of a research project which aims at evaluating the applicability of project-based action learning (PAL) to shop floor organizational learning (OL) component in a manufacturing company in Dongguan, China. How the PAL framework was introduced and implemented is described. The factors…

  20. Secret Shopping as User Experience Assessment Tool

    ERIC Educational Resources Information Center

    Boyce, Crystal M.

    2015-01-01

    Secret shopping is a form of unobtrusive evaluation that can be accomplished with minimal effort, but still produce rich results. With as few as 11 shoppers, the author was able to identify trends in user satisfaction with services provided across two entry-level desks at Illinois Wesleyan University's The Ames Library. The focus of this secret…

  1. The Great Irish Head Shop Controversy

    ERIC Educational Resources Information Center

    Ryall, Graham; Butler, Shane

    2011-01-01

    This research describes and analyses recent policy developments in Ireland in relation to the practice of selling psychoactive substances which, while not themselves illegal, mimic the effects of commonly used illegal drugs. These so-called "legal highs" had been sold in Ireland through an increasing number of "head shops"…

  2. Organizational Learning in Shop Floor Level

    ERIC Educational Resources Information Center

    Cheung, Che Keung; Geng, Shuang; Chuah, Kong Bieng; Chau, Yiu Chung; Kwong, Kar Fai

    2016-01-01

    Purpose: This paper aims to present the result of the pilot run of a research project which aims at evaluating the applicability of project-based action learning (PAL) to shop floor organizational learning (OL) component in a manufacturing company in Dongguan, China. How the PAL framework was introduced and implemented is described. The factors…

  3. Secret Shopping as User Experience Assessment Tool

    ERIC Educational Resources Information Center

    Boyce, Crystal M.

    2015-01-01

    Secret shopping is a form of unobtrusive evaluation that can be accomplished with minimal effort, but still produce rich results. With as few as 11 shoppers, the author was able to identify trends in user satisfaction with services provided across two entry-level desks at Illinois Wesleyan University's The Ames Library. The focus of this secret…

  4. Performance Support on the Shop Floor.

    ERIC Educational Resources Information Center

    Kasvi, Jyrki J. J.; Vartiainen, Matti

    2000-01-01

    Discussion of performance support on the shop floor highlights four support systems for assembly lines that incorporate personal computer workstations in local area networks and use multimedia documents. Considers new customer-focused production paradigms; organizational learning; knowledge development; and electronic performance support systems…

  5. Designing a Shopping System for Senior Citizens

    ERIC Educational Resources Information Center

    Roman, Harry T.

    2010-01-01

    It is all about serving the customer. That is how capitalism plays out. It finds a market need and then creates a product or service to address that need. The Baby Boomer generation, all 76 million, will be retiring soon. Eventually, some may find it very hard to move about and do their routine food shopping. In this article, the author's…

  6. Cluster: Metals. Course: Machine Shop. Research Project.

    ERIC Educational Resources Information Center

    Sanford - Lee County Schools, NC.

    The set of 13 units is designed for use with an instructor in actual machine shop practice and is also keyed to audio visual and textual materials. Each unit contains a series of task packages which: specify prerequisites within the series (minimum is Unit 1); provide a narrative rationale for learning; list both general and specific objectives in…

  7. Industrial Arts Curriculum Guide for General Shop.

    ERIC Educational Resources Information Center

    Hubachek, Carl H.; And Others

    This curriculum guide for general shop courses is part of a series of curriculum guides for use in the industrial arts curriculum in Connecticut. The guide provides information on the scope and sequence of the industrial arts curriculum, specific guidelines for industrial arts, program goals and objectives, and guidelines concerning special…

  8. Designing a Shopping System for Senior Citizens

    ERIC Educational Resources Information Center

    Roman, Harry T.

    2010-01-01

    It is all about serving the customer. That is how capitalism plays out. It finds a market need and then creates a product or service to address that need. The Baby Boomer generation, all 76 million, will be retiring soon. Eventually, some may find it very hard to move about and do their routine food shopping. In this article, the author's…

  9. Industrial Arts Curriculum Guide for General Shop.

    ERIC Educational Resources Information Center

    Hubachek, Carl H.; And Others

    This curriculum guide for general shop courses is part of a series of curriculum guides for use in the industrial arts curriculum in Connecticut. The guide provides information on the scope and sequence of the industrial arts curriculum, specific guidelines for industrial arts, program goals and objectives, and guidelines concerning special…

  10. Where Students Shop for Nutrition Facts.

    ERIC Educational Resources Information Center

    Teaching PreK-8, 1995

    1995-01-01

    Describes a school tour launched by a supermarket to familiarize children with basic facts about nutrition and healthful eating. Discusses visits to a perishable foods department, a shopping activity, a recipe preparation activity, and Food Pyramid activity. Suggests making enquiries about such tours with local supermarket chains and bringing it…

  11. 30 CFR 57.4761 - Underground shops.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Fire Prevention and... toxic gases from a fire originating in an underground shop where maintenance work is routinely done...

  12. 30 CFR 57.4761 - Underground shops.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... least equivalent to the door in fire and air-leakage resistance, and in physical strength. (4) If..., shall be at least equivalent to the door in fire and air-leakage resistance, and in physical strength..., routing of the mine shop air directly to an exhaust system, reversal of mechanical ventilation, or use of...

  13. 30 CFR 57.4761 - Underground shops.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Fire Prevention and..., routing of the mine shop air directly to an exhaust system, reversal of mechanical ventilation, or use of...

  14. Where Students Shop for Nutrition Facts.

    ERIC Educational Resources Information Center

    Teaching PreK-8, 1995

    1995-01-01

    Describes a school tour launched by a supermarket to familiarize children with basic facts about nutrition and healthful eating. Discusses visits to a perishable foods department, a shopping activity, a recipe preparation activity, and Food Pyramid activity. Suggests making enquiries about such tours with local supermarket chains and bringing it…

  15. School Shop Development: Research and Planning.

    ERIC Educational Resources Information Center

    Rockwell Manufacturing Co., Pittsburgh, PA.

    This facility planning guide was developed by a commercial firm for use by school personnel in planning and equiping industrial education shops. It is based on an analysis of reports made by the company's 150 field representatives and information furnished by school administrators and architects. Five fundamental planning concepts and a cycle of…

  16. The Great Irish Head Shop Controversy

    ERIC Educational Resources Information Center

    Ryall, Graham; Butler, Shane

    2011-01-01

    This research describes and analyses recent policy developments in Ireland in relation to the practice of selling psychoactive substances which, while not themselves illegal, mimic the effects of commonly used illegal drugs. These so-called "legal highs" had been sold in Ireland through an increasing number of "head shops"…

  17. Utah Integrated Shop Program. Final Report.

    ERIC Educational Resources Information Center

    Loveless, Austin G.

    To evaluate the Utah State Board of Education's Integrated Shop Program (ISP) for small rural high schools, 7 ISP schools in their 2nd year (1970-71) of the ISP were compared on 3 measures to 2 selected control schools (small rural high schools that offered vocational agricultural mechanics and industrial arts but did not offer formal courses in…

  18. Online versus conventional shopping: consumers' risk perception and regulatory focus.

    PubMed

    van Noort, Guda; Kerkhof, Peter; Fennis, Bob M

    2007-10-01

    In two experiments, the impact of shopping context on consumers' risk perceptions and regulatory focus was examined. We predicted that individuals perceive an online (vs. conventional) shopping environment as more risky and that an online shopping environment, by its risky nature, primes a prevention focus. The findings in Study 1 demonstrate these effects by using self-report measures for risk perception and prevention focus. In Study 2, we replicated these findings and demonstrated that the effect of an online shopping environment carries over to behavior in a domain unrelated to shopping.

  19. Craftsmen in the Wood Model Shop at the Lewis Flight Propulsion Laboratory

    NASA Image and Video Library

    1953-01-21

    Craftsmen work in the wood model shop at the National Advisory Committee for Aeronautics (NACA) Lewis Flight Propulsion Laboratory. The Fabrication Division created almost all of the equipment and models used at the laboratory. The Fabrication Shop building contained a number of specialized shops in the 1940s and 1950s. These included a Machine Shop, Sheet Metal Shop, Wood Model and Pattern Shop, Instrument Shop, Thermocouple Shop, Heat Treating Shop, Metallurgical Laboratory, and Fabrication Office. The Wood Model and Pattern Shop created everything from control panels and cabinets to aircraft models molds for sheet metal work.

  20. Construction of null statistics in permutation-based multiple testing for multi-factorial microarray experiments.

    PubMed

    Gao, Xin

    2006-06-15

    The parametric F-test has been widely used in the analysis of factorial microarray experiments to assess treatment effects. However, the normality assumption is often untenable for microarray experiments with small replications. Therefore, permutation-based methods are called for help to assess the statistical significance. The distribution of the F-statistics across all the genes on the array can be regarded as a mixture distribution with a proportion of statistics generated from the null distribution of no differential gene expression whereas the other proportion of statistics generated from the alternative distribution of genes differentially expressed. This results in the fact that the permutation distribution of the F-statistics may not approximate well to the true null distribution of the F-statistics. Therefore, the construction of a proper null statistic to better approximate the null distribution of F-statistic is of great importance to the permutation-based multiple testing in microarray data analysis. In this paper, we extend the ideas of constructing null statistics based on pairwise differences to neglect the treatment effects from the two-sample comparison problem to the multifactorial balanced or unbalanced microarray experiments. A null statistic based on a subpartition method is proposed and its distribution is employed to approximate the null distribution of the F-statistic. The proposed null statistic is able to accommodate unbalance in the design and is also corrected for the undue correlation between its numerator and denominator. In the simulation studies and real biological data analysis, the number of true positives and the false discovery rate (FDR) of the proposed null statistic are compared with those of the permutated version of the F-statistic. It has been shown that our proposed method has a better control of the FDRs and a higher power than the standard permutation method to detect differentially expressed genes because of the better

  1. Urban food environments and residents' shopping behaviors.

    PubMed

    Cannuscio, Carolyn C; Tappe, Karyn; Hillier, Amy; Buttenheim, Alison; Karpyn, Allison; Glanz, Karen

    2013-11-01

    Food environments may promote or undermine healthy behaviors, but questions remain regarding how individuals interact with their local food environments. This study incorporated an urban food environment audit as well as an examination of residents' food shopping behaviors within that context. In 2010, the research team audited the variety and healthfulness of foods available in 373 Philadelphia stores, using the validated Nutrition Environment Measures Survey in Stores (NEMS-S); higher scores indicate more diverse and healthful food inventories. The team also surveyed urban residents (n=514) regarding their food shopping. Descriptive and multivariate analyses (conducted in 2012) assessed variation in retail food environments and in shoppers' store choices. Corner and convenience stores were common (78.6% of food retail outlets) and had the lowest mean NEMS-S scores of any store type. Most participants (94.5%) did their primary food shopping at higher-scoring chain supermarkets, and the majority of participants did not shop at the supermarket closest to home. Supermarket offerings varied, with significantly fewer healthful foods at supermarkets closest to the homes of disadvantaged residents. In multivariate analyses, participants were significantly more likely to shop at supermarkets closest to home if those supermarkets had higher NEMS-S scores. These data suggest that, when possible, shoppers chose supermarkets that offered more variety and more healthful foods. Findings from this study also reinforce concern regarding unhealthy immediate food environments for disadvantaged residents, who disproportionately relied on nearby stores with more limited food items. Interventions to improve nutrition and health should address not only food store proximity but also diversity of healthful foods available. © 2013 American Journal of Preventive Medicine.

  2. Possible Opioid Shopping and Its Correlates.

    PubMed

    Walker, Alexander M; Weatherby, Lisa B; Cepeda, M Soledad; Bradford, Daniel; Yuan, Yingli

    2017-01-31

    We created an operational definition of possible opioid shopping in US commercial health insurance data and examined its correlates. The population consisted of 264,204 treatment courses in persons with a fill for an opioid or diuretic prescription in 2012 and a second within 18 months. We examined counts of prescribers and pharmacies and the numbers of fills and overlaps for ability to discriminate courses of opioids from diuretics, which were a negative control. The most discriminatory measure, indicating possible shopping behavior, was cross-tabulated against other prescriptions filled and diagnoses as found in insurance claims. The associations between claims characteristics and shopping behavior were assessed in a logistic regression. A definition that classified possible "moderate" or "extensive" shopping when a person obtained drug through at least three practices and at least three pharmacies over 18 months was highly discriminatory between opioid and diuretic treatment. Overlaps between fills and number of fills did not improve the discrimination. Data from insurance claims strongly predicted moderate-to-extensive levels of possible shopping (c=0.82). Prominent among 20 significant predictors were: state of residence; amount of opioid dispensed; self-payment; use of non-specialist prescribers; high use of anxiolytics, hypnotics, psychostimulants and antipsychotics; use of both immediate release (IR) and extended-release or long-acting (ER/LA) opioids. The use of three or more prescribing practices and three or more dispensing pharmacies over 18 months sharply discriminated courses of opioid treatment from courses of diuretics. This pattern of fills was additionally associated with the numbers of non-specialist and self-paid fills, the total MEQ dispensed and heavier use of drugs for anxiety, sleep, attention and psychosis.

  3. Permutation approach to finite-alphabet stationary stochastic processes based on the duality between values and orderings

    NASA Astrophysics Data System (ADS)

    Haruna, T.; Nakajima, K.

    2013-06-01

    The duality between values and orderings is a powerful tool to discuss relationships between various information-theoretic measures and their permutation analogues for discrete-time finite-alphabet stationary stochastic processes (SSPs). Applying it to output processes of hidden Markov models with ergodic internal processes, we have shown in our previous work that the excess entropy and the transfer entropy rate coincide with their permutation analogues. In this paper, we discuss two permutation characterizations of the two measures for general ergodic SSPs not necessarily having the Markov property assumed in our previous work. In the first approach, we show that the excess entropy and the transfer entropy rate of an ergodic SSP can be obtained as the limits of permutation analogues of them for the N-th order approximation by hidden Markov models, respectively. In the second approach, we employ the modified permutation partition of the set of words which considers equalities of symbols in addition to permutations of words. We show that the excess entropy and the transfer entropy rate of an ergodic SSP are equal to their modified permutation analogues, respectively.

  4. The use of permutation tests for the analysis of parallel and stepped-wedge cluster-randomized trials.

    PubMed

    Wang, Rui; De Gruttola, Victor

    2017-08-15

    We investigate the use of permutation tests for the analysis of parallel and stepped-wedge cluster-randomized trials. Permutation tests for parallel designs with exponential family endpoints have been extensively studied. The optimal permutation tests developed for exponential family alternatives require information on intraclass correlation, a quantity not yet defined for time-to-event endpoints. Therefore, it is unclear how efficient permutation tests can be constructed for cluster-randomized trials with such endpoints. We consider a class of test statistics formed by a weighted average of pair-specific treatment effect estimates and offer practical guidance on the choice of weights to improve efficiency. We apply the permutation tests to a cluster-randomized trial evaluating the effect of an intervention to reduce the incidence of hospital-acquired infection. In some settings, outcomes from different clusters may be correlated, and we evaluate the validity and efficiency of permutation test in such settings. Lastly, we propose a permutation test for stepped-wedge designs and compare its performance with mixed-effect modeling and illustrate its superiority when sample sizes are small, the underlying distribution is skewed, or there is correlation across clusters. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

  5. A Comparison of Multiscale Permutation Entropy Measures in On-Line Depth of Anesthesia Monitoring

    PubMed Central

    Li, Xiaoli; Li, Duan; Li, Yongwang; Ursino, Mauro

    2016-01-01

    Objective Multiscale permutation entropy (MSPE) is becoming an interesting tool to explore neurophysiological mechanisms in recent years. In this study, six MSPE measures were proposed for on-line depth of anesthesia (DoA) monitoring to quantify the anesthetic effect on the real-time EEG recordings. The performance of these measures in describing the transient characters of simulated neural populations and clinical anesthesia EEG were evaluated and compared. Methods Six MSPE algorithms—derived from Shannon permutation entropy (SPE), Renyi permutation entropy (RPE) and Tsallis permutation entropy (TPE) combined with the decomposition procedures of coarse-graining (CG) method and moving average (MA) analysis—were studied. A thalamo-cortical neural mass model (TCNMM) was used to generate noise-free EEG under anesthesia to quantitatively assess the robustness of each MSPE measure against noise. Then, the clinical anesthesia EEG recordings from 20 patients were analyzed with these measures. To validate their effectiveness, the ability of six measures were compared in terms of tracking the dynamical changes in EEG data and the performance in state discrimination. The Pearson correlation coefficient (R) was used to assess the relationship among MSPE measures. Results CG-based MSPEs failed in on-line DoA monitoring at multiscale analysis. In on-line EEG analysis, the MA-based MSPE measures at 5 decomposed scales could track the transient changes of EEG recordings and statistically distinguish the awake state, unconsciousness and recovery of consciousness (RoC) state significantly. Compared to single-scale SPE and RPE, MSPEs had better anti-noise ability and MA-RPE at scale 5 performed best in this aspect. MA-TPE outperformed other measures with faster tracking speed of the loss of unconsciousness. Conclusions MA-based multiscale permutation entropies have the potential for on-line anesthesia EEG analysis with its simple computation and sensitivity to drug effect

  6. Integrated online job-shop scheduling system

    NASA Astrophysics Data System (ADS)

    Zhao, Xing; Chen, Kuan H.; Luh, Peter B.; Chiueh, T. D.; Chang, ShihChang; Thakur, Lakshman S.

    1999-11-01

    The rapid development of information technology and e- commerce requires fast response form scheduling systems. Based on the Lagrangian relaxation approach for job shop scheduling, this paper present an integrated system that will generate schedules quickly. The Lagrangian relaxation approach is an iterative optimization process, where dynamic programming is solved in each iteration. Since dynamic programming is computational expensive especially for large problems, this paper develops the simplified dynamic programming, which will cut the computation time of each iteration by one order. Furthermore, a digital circuit to be embedded in PC is designed to implement the iterative optimization algorithm, leading to another order of speed improvement. The resulting integrated scheduling system consists of the hardware for optimization and the related software. It is estimated that two orders of magnitude gain in speed can be obtained, which will make on-line scheduling for practical job shops possible.

  7. [Art nouveau: pharmacy shops in Nancy].

    PubMed

    Leclerc, Florence; Labrude, Pierre

    2002-01-01

    At the beginning of the 20th century, an important artistic activity develops in Nancy. The "Ecole de Nancy" transforms a provincial city into one of the metropolis of "Art Nouveau". The pharmacists participate at the activity of their town and eight of them choose the new style for their pharmacy. In 1902, Rosfelder is the first to modify his shop, and later, Jacques, Delidon, Mouzin, Godfrin brothers, Monal and Fandre, before, during and after the First World War, have a same step. For the ornament, the artists use plants derived from local medicinal flora. "Art Nouveau", adept of curves, appears to be ideal to symbolize vegetable kingdom. In these pharmacy shops, fine arts join materia medica.

  8. Analysis of dispatching rules in a stochastic dynamic job shop manufacturing system with sequence-dependent setup times

    NASA Astrophysics Data System (ADS)

    Sharma, Pankaj; Jain, Ajai

    2014-12-01

    Stochastic dynamic job shop scheduling problem with consideration of sequence-dependent setup times are among the most difficult classes of scheduling problems. This paper assesses the performance of nine dispatching rules in such shop from makespan, mean flow time, maximum flow time, mean tardiness, maximum tardiness, number of tardy jobs, total setups and mean setup time performance measures viewpoint. A discrete event simulation model of a stochastic dynamic job shop manufacturing system is developed for investigation purpose. Nine dispatching rules identified from literature are incorporated in the simulation model. The simulation experiments are conducted under due date tightness factor of 3, shop utilization percentage of 90% and setup times less than processing times. Results indicate that shortest setup time (SIMSET) rule provides the best performance for mean flow time and number of tardy jobs measures. The job with similar setup and modified earliest due date (JMEDD) rule provides the best performance for makespan, maximum flow time, mean tardiness, maximum tardiness, total setups and mean setup time measures.

  9. Switching Circuit for Shop Vacuum System

    NASA Technical Reports Server (NTRS)

    Burley, R. K.

    1987-01-01

    No internal connections to machine tools required. Switching circuit controls vacuum system draws debris from grinders and sanders in machine shop. Circuit automatically turns on vacuum system whenever at least one sander or grinder operating. Debris safely removed, even when operator neglects to turn on vacuum system manually. Pickup coils sense alternating magnetic fields just outside operating machines. Signal from any coil or combination of coils causes vacuum system to be turned on.

  10. Heuristics for Job-Shop Scheduling

    DTIC Science & Technology

    1988-01-01

    None 11. KEY WORDS (Continue on fewer&* Slde II neceseome aid idontify by Wock numberh) scheduling job-shop heuristic geometric 20. ABSTRACT (C nRtnue...partial fulfillment of the requirements for the degree of Doctor of Science in Mechanical Engineering. Abstract Two methods of obtaining approximate... Representation 27 2.1 Cartesian Completion Space. .. .. .. .. .I.. ... ... ... ... 27 2.2 Capabilities and Limitations of the Representation

  11. Aesthetic quality inference for online fashion shopping

    NASA Astrophysics Data System (ADS)

    Chen, Ming; Allebach, Jan

    2014-03-01

    On-line fashion communities in which participants post photos of personal fashion items for viewing and possible purchase by others are becoming increasingly popular. Generally, these photos are taken by individuals who have no training in photography with low-cost mobile phone cameras. It is desired that photos of the products have high aesthetic quality to improve the users' online shopping experience. In this work, we design features for aesthetic quality inference in the context of online fashion shopping. Psychophysical experiments are conducted to construct a database of the photos' aesthetic evaluation, specifically for photos from an online fashion shopping website. We then extract both generic low-level features and high-level image attributes to represent the aesthetic quality. Using a support vector machine framework, we train a predictor of the aesthetic quality rating based on the feature vector. Experimental results validate the efficacy of our approach. Metadata such as the product type are also used to further improve the result.

  12. Weighted fractional permutation entropy and fractional sample entropy for nonlinear Potts financial dynamics

    NASA Astrophysics Data System (ADS)

    Xu, Kaixuan; Wang, Jun

    2017-02-01

    In this paper, recently introduced permutation entropy and sample entropy are further developed to the fractional cases, weighted fractional permutation entropy (WFPE) and fractional sample entropy (FSE). The fractional order generalization of information entropy is utilized in the above two complexity approaches, to detect the statistical characteristics of fractional order information in complex systems. The effectiveness analysis of proposed methods on the synthetic data and the real-world data reveals that tuning the fractional order allows a high sensitivity and more accurate characterization to the signal evolution, which is useful in describing the dynamics of complex systems. Moreover, the numerical research on nonlinear complexity behaviors is compared between the returns series of Potts financial model and the actual stock markets. And the empirical results confirm the feasibility of the proposed model.

  13. Extension of the Dynasearch to the Two-Machine Permutation Flowshop Scheduling Problem

    NASA Astrophysics Data System (ADS)

    Tanaka, Shunji

    The purpose of this study is to construct a solution algorithm for the two-machine permutation flowshop problem based on the dynasearch. The dynasearch is an efficient local search algorithm that employs a special neighborhood structure called dynasearch swap neighborhood. Its primary advantage is that the neighborhood of a solution can be explored in polynomial time although it is composed of an exponential number of solutions. The dynasearch for machine scheduling was originally developed for the single-machine total weighted tardiness problem. Then, it was extended to the problem with idle time and setup times. This study further extends the dynasearch to the two-machine permutation flowshop problem and its effectiveness is examined by numerical experiments for both total weighted tardiness and total weighted earliness-tardiness objectives.

  14. A better alternative to stratified permuted block design for subject randomization in clinical trials

    PubMed Central

    Zhao, Wenle

    2014-01-01

    SUMMARY Stratified permuted block randomization has been the dominant covariate-adaptive randomization procedure in clinical trials for several decades. Its high probability of deterministic assignment and low capacity of covariate balancing have been well recognized. The popularity of this sub-optimal method is largely due to its simplicity in implementation and the lack of better alternatives. Proposed in this paper is a two-stage covariate-adaptive randomization procedure that uses the block urn design or the big stick design in stage one to restrict the treatment imbalance within each covariate stratum, and uses the biased-coin minimization method in stage two to control imbalances in the distribution of additional covariates that are not included in the stratification algorithm. Analytical and simulation results show that the new randomization procedure significantly reduces the probability of deterministic assignments, and improves the covariate balancing capacity when compared to the traditional stratified permuted block randomization. PMID:25043719

  15. A better alternative to stratified permuted block design for subject randomization in clinical trials.

    PubMed

    Zhao, Wenle

    2014-12-30

    Stratified permuted block randomization has been the dominant covariate-adaptive randomization procedure in clinical trials for several decades. Its high probability of deterministic assignment and low capacity of covariate balancing have been well recognized. The popularity of this sub-optimal method is largely due to its simplicity in implementation and the lack of better alternatives. Proposed in this paper is a two-stage covariate-adaptive randomization procedure that uses the block urn design or the big stick design in stage one to restrict the treatment imbalance within each covariate stratum, and uses the biased-coin minimization method in stage two to control imbalances in the distribution of additional covariates that are not included in the stratification algorithm. Analytical and simulation results show that the new randomization procedure significantly reduces the probability of deterministic assignments, and improve the covariate balancing capacity when compared to the traditional stratified permuted block randomization. Copyright © 2014 John Wiley & Sons, Ltd.

  16. Multiple-image encryption algorithm based on mixed image element and permutation

    NASA Astrophysics Data System (ADS)

    Zhang, Xiaoqiang; Wang, Xuesong

    2017-05-01

    To improve encryption efficiency and facilitate the secure transmission of multiple digital images, by defining the pure image element and mixed image element, this paper presents a new multiple-image encryption (MIE) algorithm based on the mixed image element and permutation, which can simultaneously encrypt any number of images. Firstly, segment the original images into pure image elements; secondly, scramble all the pure image elements with the permutation generated by the piecewise linear chaotic map (PWLCM) system; thirdly, combine mixed image elements into scrambled images; finally, diffuse the content of mixed image elements by performing the exclusive OR (XOR) operation among scrambled images and the chaotic image generated by another PWLCM system. The comparison with two similar algorithms is made. Experimental results and algorithm analyses show that the proposed MIE algorithm is very simple and efficient, which is suitable for practical image encryption.

  17. Permutation tests for comparing marginal survival functions with clustered failure time data.

    PubMed

    Cai, J; Shen, Y

    2000-11-15

    We propose a class of two-sample non-parametric permutation tests to compare the marginal survival distributions of two groups when the failure times are correlated within cluster, with clusters nested within each group. The permutation distribution effectively takes into account the correlation between failure times within a cluster. The method is able to handle data with clusters of either fixed or variable sizes. Moreover, this class of test statistics is sensitive to various alternatives. The size and power of the proposed tests are assessed by a series of simulation studies. The method is illustrated by application to data from the Hypertension Detection and Follow-up program trial. Copyright 2000 John Wiley and Sons, Ltd.

  18. A new bioinformatics approach to natural protein collections: permutation structure contrasts of viral and cellular systems.

    PubMed

    Graham, Daniel J

    2013-04-01

    Biological cells and viruses operate by different replication and symmetry paradigms. Cells are able to replicate independently and express little spatial symmetry; viruses require cells for replication while manifesting high symmetry. The author inquired whether different paradigms were reflected in the permutations of amino acid sequences. The hypothesis was that the permutation structure level and symmetry within viral protein collections exceed that of living cells. The rationale was that one symmetry aspect generally accompanies and promotes others in a system. The inquiry was readily answered given abundant sequence archives for proteins. The analysis of collections from diverse viral and cellular sources lends strong support. Additional insights into protein primary structure, the design of collections, and the role of information are provided as well.

  19. Storage and computationally efficient permutations of factorized covariance and square-root information matrices

    NASA Technical Reports Server (NTRS)

    Muellerschoen, R. J.

    1988-01-01

    A unified method to permute vector-stored upper-triangular diagonal factorized covariance (UD) and vector stored upper-triangular square-root information filter (SRIF) arrays is presented. The method involves cyclical permutation of the rows and columns of the arrays and retriangularization with appropriate square-root-free fast Givens rotations or elementary slow Givens reflections. A minimal amount of computation is performed and only one scratch vector of size N is required, where N is the column dimension of the arrays. To make the method efficient for large SRIF arrays on a virtual memory machine, three additional scratch vectors each of size N are used to avoid expensive paging faults. The method discussed is compared with the methods and routines of Bierman's Estimation Subroutine Library (ESL).

  20. A permutation information theory tour through different interest rate maturities: the Libor case.

    PubMed

    Bariviera, Aurelio Fernández; Guercio, María Belén; Martinez, Lisana B; Rosso, Osvaldo A

    2015-12-13

    This paper analyses Libor interest rates for seven different maturities and referred to operations in British pounds, euros, Swiss francs and Japanese yen, during the period 2001-2015. The analysis is performed by means of two quantifiers derived from information theory: the permutation Shannon entropy and the permutation Fisher information measure. An anomalous behaviour in the Libor is detected in all currencies except euros during the years 2006-2012. The stochastic switch is more severe in one, two and three months maturities. Given the special mechanism of Libor setting, we conjecture that the behaviour could have been produced by the manipulation that was uncovered by financial authorities. We argue that our methodology is pertinent as a market overseeing instrument. © 2015 The Author(s).

  1. Computationally efficient permutation-based confidence interval estimation for tail-area FDR.

    PubMed

    Millstein, Joshua; Volfson, Dmitri

    2013-01-01

    Challenges of satisfying parametric assumptions in genomic settings with thousands or millions of tests have led investigators to combine powerful False Discovery Rate (FDR) approaches with computationally expensive but exact permutation testing. We describe a computationally efficient permutation-based approach that includes a tractable estimator of the proportion of true null hypotheses, the variance of the log of tail-area FDR, and a confidence interval (CI) estimator, which accounts for the number of permutations conducted and dependencies between tests. The CI estimator applies a binomial distribution and an overdispersion parameter to counts of positive tests. The approach is general with regards to the distribution of the test statistic, it performs favorably in comparison to other approaches, and reliable FDR estimates are demonstrated with as few as 10 permutations. An application of this approach to relate sleep patterns to gene expression patterns in mouse hypothalamus yielded a set of 11 transcripts associated with 24 h REM sleep [FDR = 0.15 (0.08, 0.26)]. Two of the corresponding genes, Sfrp1 and Sfrp4, are involved in wnt signaling and several others, Irf7, Ifit1, Iigp2, and Ifih1, have links to interferon signaling. These genes would have been overlooked had a typical a priori FDR threshold such as 0.05 or 0.1 been applied. The CI provides the flexibility for choosing a significance threshold based on tolerance for false discoveries and precision of the FDR estimate. That is, it frees the investigator to use a more data-driven approach to define significance, such as the minimum estimated FDR, an option that is especially useful for weak effects, often observed in studies of complex diseases.

  2. Online quantitative proteomics p-value calculator for permutation-based statistical testing of peptide ratios.

    PubMed

    Chen, David; Shah, Anup; Nguyen, Hien; Loo, Dorothy; Inder, Kerry L; Hill, Michelle M

    2014-09-05

    The utility of high-throughput quantitative proteomics to identify differentially abundant proteins en-masse relies on suitable and accessible statistical methodology, which remains mostly an unmet need. We present a free web-based tool, called Quantitative Proteomics p-value Calculator (QPPC), designed for accessibility and usability by proteomics scientists and biologists. Being an online tool, there is no requirement for software installation. Furthermore, QPPC accepts generic peptide ratio data generated by any mass spectrometer and database search engine. Importantly, QPPC utilizes the permutation test that we recently found to be superior to other methods for analysis of peptide ratios because it does not assume normal distributions.1 QPPC assists the user in selecting significantly altered proteins based on numerical fold change, or standard deviation from the mean or median, together with the permutation p-value. Output is in the form of comma separated values files, along with graphical visualization using volcano plots and histograms. We evaluate the optimal parameters for use of QPPC, including the permutation level and the effect of outlier and contaminant peptides on p-value variability. The optimal parameters defined are deployed as default for the web-tool at http://qppc.di.uq.edu.au/ .

  3. Permutation Mutual Information: A Novel Approach for Measuring Neuronal Phase-Amplitude Coupling.

    PubMed

    Cheng, Ning; Li, Qun; Wang, Sitong; Wang, Rubin; Zhang, Tao

    2017-10-05

    Cross-frequency phase-amplitude coupling (PAC) in neuronal oscillations network plays an important functional role in large scale neuronal communication and neuronal encoding. In the present study, a novel approach named permutation mutual information (PMI) was applied in measuring PAC. It is derived from the permutation entropy based on the mutual information theory, by which the mutual information of permutations of two time series can be evaluated. In order to verify the ability of PMI, a numerical test was performed by using both simulation data and experimental data. The performances of PMI were compared with that of two well-known methods, which were the mean vector length (MVL) and the modulation index (MI). It was found that the performance of PMI was similar to that of MI when measuring PAC intensity, but the coupling sensitivity of PMI was the highest among all these three approaches. Moreover, there was the lowest sensitivity in the MVL measurement, suggesting that MVL was a more conservative approach in detecting the existence of PAC. In addition, an ROC analysis showed that PMI performed better in measuring PAC compared to that of others. Furthermore, the experimental data, obtained from rats' hippocampal CA3 regions, were analyzed by using the three approaches. The result was essentially in line with that of the simulation performances. In a word, the results suggest that PMI is a better choice for assessing PAC under the certain conditions.

  4. Revisiting the European sovereign bonds with a permutation-information-theory approach

    NASA Astrophysics Data System (ADS)

    Fernández Bariviera, Aurelio; Zunino, Luciano; Guercio, María Belén; Martinez, Lisana B.; Rosso, Osvaldo A.

    2013-12-01

    In this paper we study the evolution of the informational efficiency in its weak form for seventeen European sovereign bonds time series. We aim to assess the impact of two specific economic situations in the hypothetical random behavior of these time series: the establishment of a common currency and a wide and deep financial crisis. In order to evaluate the informational efficiency we use permutation quantifiers derived from information theory. Specifically, time series are ranked according to two metrics that measure the intrinsic structure of their correlations: permutation entropy and permutation statistical complexity. These measures provide the rectangular coordinates of the complexity-entropy causality plane; the planar location of the time series in this representation space reveals the degree of informational efficiency. According to our results, the currency union contributed to homogenize the stochastic characteristics of the time series and produced synchronization in the random behavior of them. Additionally, the 2008 financial crisis uncovered differences within the apparently homogeneous European sovereign markets and revealed country-specific characteristics that were partially hidden during the monetary union heyday.

  5. Input permutation method to detect active voxels in fMRI study☆

    PubMed Central

    Lee, Sang H.; Lim, Johan; Park, DoHwan; Biswal, Bharat B.; Petkova, Eva

    2013-01-01

    Correctly identifying voxels or regions of interest (ROI) that actively respond to a given stimulus is often an important objective/step in many functional magnetic resonance imaging (fMRI) studies. In this article, we study a nonparametric method to detect active voxels, which makes minimal assumption about the distribution of blood oxygen level-dependent (BOLD) signals. Our proposal has several interesting features. It uses time lagged correlation to take into account the delay in response to the stimulus, due to hemodynamic variations. We introduce an input permutation method (IPM), a type of block permutation method, to approximate the null distribution of the test statistic. Also, we propose to pool the permutation-derived statistics of preselected voxels for a better approximation to the null distribution. Finally, we control multiple testing error rate using the local false discovery rate (FDR) by Efron [Correlation and large-scale simultaneous hypothesis testing. J Am Stat Assoc 102 (2007) 93–103] and Park et al. [Estimation of empirical null using a mixture of normals and its use in local false discovery rate. Comput Stat Data Anal 55 (2011) 2421–2432] to select the active voxels. PMID:22819177

  6. Permutation entropy based time series analysis: Equalities in the input signal can lead to false conclusions

    NASA Astrophysics Data System (ADS)

    Zunino, Luciano; Olivares, Felipe; Scholkmann, Felix; Rosso, Osvaldo A.

    2017-06-01

    A symbolic encoding scheme, based on the ordinal relation between the amplitude of neighboring values of a given data sequence, should be implemented before estimating the permutation entropy. Consequently, equalities in the analyzed signal, i.e. repeated equal values, deserve special attention and treatment. In this work, we carefully study the effect that the presence of equalities has on permutation entropy estimated values when these ties are symbolized, as it is commonly done, according to their order of appearance. On the one hand, the analysis of computer-generated time series is initially developed to understand the incidence of repeated values on permutation entropy estimations in controlled scenarios. The presence of temporal correlations is erroneously concluded when true pseudorandom time series with low amplitude resolutions are considered. On the other hand, the analysis of real-world data is included to illustrate how the presence of a significant number of equal values can give rise to false conclusions regarding the underlying temporal structures in practical contexts.

  7. Tolerance of a knotted near infrared fluorescent protein to random circular permutation

    PubMed Central

    Pandey, Naresh; Kuypers, Brianna E.; Nassif, Barbara; Thomas, Emily E.; Alnahhas, Razan N.; Segatori, Laura; Silberg, Jonathan J.

    2016-01-01

    Bacteriophytochrome photoreceptors (BphP) are knotted proteins that have been developed as near-infrared fluorescent protein (iRFP) reporters of gene expression. To explore how rearrangements in the peptides that interlace into the knot within the BphP photosensory core affect folding, we subjected iRFP to random circular permutation using an improved transposase mutagenesis strategy and screened for variants that fluoresce. We identified twenty seven circularly permuted iRFP that display biliverdin-dependent fluorescence in Escherichia coli. The variants with the brightest whole cell fluorescence initiated translation at residues near the domain linker and knot tails, although fluorescent variants were discovered that initiated translation within the PAS and GAF domains. Circularly permuted iRFP retained sufficient cofactor affinity to fluoresce in tissue culture without the addition of biliverdin, and one variant displayed enhanced fluorescence when expressed in bacteria and tissue culture. This variant displayed a similar quantum yield as iRFP, but exhibited increased resistance to chemical denaturation, suggesting that the observed signal increase arose from more efficient protein maturation. These results show how the contact order of a knotted BphP can be altered without disrupting chromophore binding and fluorescence, an important step towards the creation of near-infrared biosensors with expanded chemical-sensing functions for in vivo imaging. PMID:27304983

  8. Permutation entropy and statistical complexity analysis of turbulence in laboratory plasmas and the solar wind.

    PubMed

    Weck, P J; Schaffner, D A; Brown, M R; Wicks, R T

    2015-02-01

    The Bandt-Pompe permutation entropy and the Jensen-Shannon statistical complexity are used to analyze fluctuating time series of three different turbulent plasmas: the magnetohydrodynamic (MHD) turbulence in the plasma wind tunnel of the Swarthmore Spheromak Experiment (SSX), drift-wave turbulence of ion saturation current fluctuations in the edge of the Large Plasma Device (LAPD), and fully developed turbulent magnetic fluctuations of the solar wind taken from the Wind spacecraft. The entropy and complexity values are presented as coordinates on the CH plane for comparison among the different plasma environments and other fluctuation models. The solar wind is found to have the highest permutation entropy and lowest statistical complexity of the three data sets analyzed. Both laboratory data sets have larger values of statistical complexity, suggesting that these systems have fewer degrees of freedom in their fluctuations, with SSX magnetic fluctuations having slightly less complexity than the LAPD edge I(sat). The CH plane coordinates are compared to the shape and distribution of a spectral decomposition of the wave forms. These results suggest that fully developed turbulence (solar wind) occupies the lower-right region of the CH plane, and that other plasma systems considered to be turbulent have less permutation entropy and more statistical complexity. This paper presents use of this statistical analysis tool on solar wind plasma, as well as on an MHD turbulent experimental plasma.

  9. Quantum one-way permutation over the finite field of two elements

    NASA Astrophysics Data System (ADS)

    de Castro, Alexandre

    2017-06-01

    In quantum cryptography, a one-way permutation is a bounded unitary operator U:{H} → {H} on a Hilbert space {H} that is easy to compute on every input, but hard to invert given the image of a random input. Levin (Probl Inf Transm 39(1):92-103, 2003) has conjectured that the unitary transformation g(a,x)=(a,f(x)+ax), where f is any length-preserving function and a,x \\in {GF}_{{2}^{\\Vert x\\Vert }}, is an information-theoretically secure operator within a polynomial factor. Here, we show that Levin's one-way permutation is provably secure because its output values are four maximally entangled two-qubit states, and whose probability of factoring them approaches zero faster than the multiplicative inverse of any positive polynomial poly( x) over the Boolean ring of all subsets of x. Our results demonstrate through well-known theorems that existence of classical one-way functions implies existence of a universal quantum one-way permutation that cannot be inverted in subexponential time in the worst case.

  10. Multi-dimensional permutation-modulation format for coherent optical communications.

    PubMed

    Ishimura, Shota; Kikuchi, Kazuro

    2015-06-15

    We introduce the multi-dimensional permutation-modulation format in coherent optical communication systems and analyze its performance, focusing on the power efficiency and the spectral efficiency. In the case of four-dimensional (4D) modulation, the polarization-switched quadrature phase-shift keying (PS-QPSK) modulation format and the polarization quadrature-amplitude modulation (POL-QAM) format can be classified into the permutation modulation format. Other than these well-known modulation formats, we find novel modulation formats trading-off between the power efficiency and the spectral efficiency. With the increase in the dimension, the spectral efficiency can more closely approach the channel capacity predicted from the Shannon's theory. We verify these theoretical characteristics through computer simulations of the symbol-error rate (SER) and bit-error rate (BER) performances. For example, the newly-found eight-dimensional (8D) permutation-modulation format can improve the spectral efficiency up to 2.75 bit/s/Hz/pol/channel, while the power penalty against QPSK is about 1 dB at BER=10(-3).

  11. Replica-Permutation Method with the Suwa-Todo Algorithm beyond the Replica-Exchange Method.

    PubMed

    Itoh, Satoru G; Okumura, Hisashi

    2013-01-08

    We propose a new method for molecular dynamics and Monte Carlo simulations, which is referred to as the replica-permutation method (RPM), to realize more efficient sampling than the replica-exchange method (REM). In RPM, not only exchanges between two replicas but also permutations among more than two replicas are performed. Furthermore, instead of the Metropolis algorithm, the Suwa-Todo algorithm is employed for replica-permutation trials to minimize its rejection ratio. We applied RPM to particles in a double-well potential energy, Met-enkephalin in a vacuum, and a C-peptide analog of ribonuclease A in explicit water. For comparison purposes, replica-exchange molecular dynamics simulations were also performed. As a result, RPM sampled not only the temperature space but also the conformational space more efficiently than REM for all systems. From our simulations of C-peptide, we obtained the α-helix structure with salt bridges between Gly2 and Arg10, which is known in experiments. Calculating its free-energy landscape, the folding pathway was revealed from an extended structure to the α-helix structure with the salt bridges. We found that the folding pathway consists of the two steps: The first step is the "salt-bridge formation step," and the second step is the "α-helix formation step."

  12. Forecasting of indirect consumables for a Job Shop

    NASA Astrophysics Data System (ADS)

    Shakeel, M.; Khan, S.; Khan, W. A.

    2016-08-01

    A job shop has an arrangement where similar machines (Direct consumables) are grouped together and use indirect consumables to produce a product. The indirect consumables include hack saw blades, emery paper, painting brush etc. The job shop is serving various orders at a particular time for the optimal operation of job shop. Forecasting is required to predict the demand of direct and indirect consumables in a job shop. Forecasting is also needed to manage lead time, optimize inventory cost and stock outs. The objective of this research is to obtain the forecast for indirect consumables. The paper shows how job shop can manage their indirect consumables more accurately by establishing a new technique of forecasting. This results in profitable use of job shop by multiple users.

  13. Social image of students who shop and don't shop online.

    PubMed

    Lammers, H Bruce; Curren, Mary T; Cours, Deborah; Lammers, Marilyn L

    2003-06-01

    A descriptive survey of a stratified random sample of 326 undergraduates from a large, diverse university in Los Angeles was conducted to assess whether resistance to online shopping might be, in part, related to negative social perceptions of those who shop online. Indirect questioning showed that students perceived online student shoppers as more lazy and less likely to fear for the safety and security of others but also as more trustworthy, attractive, successful, and smart. Differences in social perceptions were not related to these students' own online spending.

  14. 13. Detail of doubledoor opening between machine shop section of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. Detail of double-door opening between machine shop section of roundhouse and engine house section of roundhouse. Engine house visible through rectangular opening. At one time the opening extended to the intrados of the arch above the doorway, allowing railroad engines to fit inside the machine shop. View to east. - Duluth & Iron Range Rail Road Company Shops, Roundhouse, Southwest of downtown Two Harbors, northwest of Agate Bay, Two Harbors, Lake County, MN

  15. 4. Elevation, looking southwest, with Machine Shop and Goliath traveling ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Elevation, looking southwest, with Machine Shop and Goliath traveling crane in background. - General Dynamics Corporation Shipyard, American Revolver Crane, 97 East Howard Street, Quincy, Norfolk County, MA

  16. View of book shop on elevator reboarding level Washington ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of book shop on elevator reboarding level - Washington Monument, High ground West of Fifteenth Street, Northwest, between Independence & Constitution Avenues, Washington, District of Columbia, DC

  17. Central of Georgia Railway, Savannah Repair Shops & Terminal Facilities, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Central of Georgia Railway, Savannah Repair Shops & Terminal Facilities, Combination Smokestack, Water Tank & Privies, Bounded by West Broad, Jones, West Boundary & Hull Streets, Savannah, Chatham County, GA

  18. Central of Georgia Railway, Savannah Repair Shops & Terminal Facilities, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Central of Georgia Railway, Savannah Repair Shops & Terminal Facilities, Brick Storage Vaults under Jones Street, Bounded by West Broad, Jones, West Boundary & Hull Streets, Savannah, Chatham County, GA

  19. Interior view of second floor brace shop partition walls and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior view of second floor brace shop partition walls and cobbler's bench, facing west. - Gorgas Hospital, Administration & Clinics Building, Culebra Road, Balboa Heights, Former Panama Canal Zone, CZ

  20. Physical Connectivity Mapping by Circular Permutation of Human Telomerase RNA Reveals New Regions Critical for Activity and Processivity

    PubMed Central

    Mefford, Melissa A.

    2015-01-01

    Telomerase is a specialized ribonucleoprotein complex that extends the 3′ ends of chromosomes to counteract telomere shortening. However, increased telomerase activity is associated with ∼90% of human cancers. The telomerase enzyme minimally requires an RNA (hTR) and a specialized reverse transcriptase protein (TERT) for activity in vitro. Understanding the structure-function relationships within hTR has important implications for human disease. For the first time, we have tested the physical-connectivity requirements in the 451-nucleotide hTR RNA using circular permutations, which reposition the 5′ and 3′ ends. Our extensive in vitro analysis identified three classes of hTR circular permutants with altered function. First, circularly permuting 3′ of the template causes specific defects in repeat-addition processivity, revealing that the template recognition element found in ciliates is conserved in human telomerase RNA. Second, seven circular permutations residing within the catalytically important core and CR4/5 domains completely abolish telomerase activity, unveiling mechanistically critical portions of these domains. Third, several circular permutations between the core and CR4/5 significantly increase telomerase activity. Our extensive circular permutation results provide insights into the architecture and coordination of human telomerase RNA and highlight where the RNA could be targeted for the development of antiaging and anticancer therapeutics. PMID:26503788

  1. Aft Engine shop worker removes a heat shield on Columbia's main engines

    NASA Technical Reports Server (NTRS)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. -- Doug Buford, with the Aft Engine shop, works at removing a heat shield on Columbia, in the Orbiter Processing Facility. After small cracks were discovered on the LH2 Main Propulsion System (MPS) flow liners in two other orbiters, program managers decided to move forward with inspections on Columbia before clearing it for flight on STS-107. After removal of the heat shields, the three main engines will be removed. Inspections of the flow liners will follow. The July 19 launch of Columbia on STS-107 has been delayed a few weeks

  2. Aft Engine shop worker removes a heat shield on Columbia's main engines

    NASA Technical Reports Server (NTRS)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. -- Doug Buford (top), with the Aft Engine shop, along with another worker, removes a heat shield on one of Columbia's engines. After small cracks were discovered on the LH2 Main Propulsion System (MPS) flow liners in two other orbiters, program managers decided to move forward with inspections on Columbia before clearing it for flight on STS-107. After removal of the heat shields, the three main engines will be removed. Inspections of the flow liners will follow. The July 19 launch of Columbia on STS-107 has been delayed a few weeks

  3. Aft Engine shop worker removes a heat shield on Columbia's main engines

    NASA Technical Reports Server (NTRS)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. - Doug Buford, with the Aft Engine shop, works at removing a heat shield on Columbia, in the Orbiter Processing Facility. After small cracks were discovered on the LH2 Main Propulsion System (MPS) flow liners in two other orbiters, program managers decided to move forward with inspections on Columbia before clearing it for flight on STS-107. After removal of the heat shields, the three main engines will be removed. Inspections of the flow liners will follow. The July 19 launch of Columbia on STS-107 has been delayed a few weeks

  4. Verification Tools Secure Online Shopping, Banking

    NASA Technical Reports Server (NTRS)

    2010-01-01

    Just like rover or rocket technology sent into space, the software that controls these technologies must be extensively tested to ensure reliability and effectiveness. Ames Research Center invented the open-source Java Pathfinder (JPF) toolset for the deep testing of Java-based programs. Fujitsu Labs of America Inc., based in Sunnyvale, California, improved the capabilities of the JPF Symbolic Pathfinder tool, establishing the tool as a means of thoroughly testing the functionality and security of Web-based Java applications such as those used for Internet shopping and banking.

  5. A New Look for the Shopping Mall

    NASA Technical Reports Server (NTRS)

    1985-01-01

    STRUCTO-FAB, a product of Owens-Corning Fiberglas Corporation, is a lightweight but extremely durable tent-like material made of Fiberglas coated with Teflon. It transmits daylight with a reduced need for artificial lighting. It is an outgrowth of a material formulated by NASA in 1967 as a new space suit fabric. Owens-Corning and DuPont provided the original material, which was the basis for Structo-Fab, a permanent architectural fabric used for shopping malls, sports stadiums, etc.

  6. Shopping for price in medical care.

    PubMed

    Ginsburg, Paul B

    2007-01-01

    Insurers are well positioned to support their enrollees in shopping for care because of their ability to analyze complex data--reflecting both their negotiated discounts and the enrollee's benefit structure--should they decide to commit resources to this task. Government transparency initiatives can help those who are uninsured or want to use out-of-network providers with data on prices and all patients by gathering and disseminating data on quality. But clumsy requirements to disclose insurer-provider contracts could lead to higher prices. Greater price transparency might help curb rising costs, but many overstate the likely magnitude of its contribution.

  7. VIEW WESTLEFTBUILDING 7 MACHINE SHOP (1890) CENTERBUILDING 3 SOUTH ROPE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW WEST-LEFT-BUILDING 7 MACHINE SHOP (1890) CENTER-BUILDING 3 SOUTH ROPE SHOP (LEFT 1929, RIGHT 1911) RIGHT-BUILDING 10 CLINTON STREET STOREHOUSE (1927) - John A. Roebling's Sons Company & American Steel & Wire Company, South Broad, Clark, Elmer, Mott & Hudson Streets, Trenton, Mercer County, NJ

  8. VIEW NORTHEASTLEFTBUILDING 110 CARPENTER SHOP (1908) LEFT CENTERBUILDING 105 ENGINE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW NORTHEAST-LEFT-BUILDING 110 CARPENTER SHOP (1908) LEFT CENTER-BUILDING 105 ENGINE HOUSE (1917) RIGHT-BUILDING 104 BOILER HOUSE (1916) RIGHT-BUILDINGS 102 & 101 ELMER STREET & CLARK STREET ROPE SHOPS (1917) - John A. Roebling's Sons Company & American Steel & Wire Company, South Broad, Clark, Elmer, Mott & Hudson Streets, Trenton, Mercer County, NJ

  9. 44. Cross section of the Blacksmith Shop from Construction Drawing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    44. Cross section of the Blacksmith Shop from Construction Drawing 2042-F-15, entitled Machine and Blacksmith Shop; Plan, Elevations, and Sections. (Original drawing, in the possession of Wyre Dick and Company, Livingston, New Jersey.) - Central Railroad of New Jersey, Engine Terminal, Jersey City, Hudson County, NJ

  10. Interior of shop, showing the reheat furnaces; the vehicle in ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior of shop, showing the reheat furnaces; the vehicle in the center is a charging machine the operator of which manipulates steel ingots in the furnace, as well as in the adjacent forging hammers - Bethlehem Steel Corporation, South Bethlehem Works, Tool Steel-Electric Furnace Shop, Along Lehigh River, North of Fourth Street, West of Minsi Trail Bridge, Bethlehem, Northampton County, PA

  11. View southwest of machine shops, building 18 section visible in ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View southwest of machine shops, building 18 section visible in foreground; building 16 section on left. This structure consists of two formerly separate buildings. Jet Lowe, Haer staff photographer, summer 1995. - Naval Base Philadelphia-Philadelphia Naval Shipyard, Machine Shops, League Island, Philadelphia, Philadelphia County, PA

  12. 10. INTERIOR OF THE VERTICAL FURNACE BUILDING OF MACHINE SHOP ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. INTERIOR OF THE VERTICAL FURNACE BUILDING OF MACHINE SHOP No. 2. STRUCTURE IN THE FOREGROUND IS THE UPENDER. THE QUENCH TOWER AND FURNACES ARE IN THE BACKGROUND. - U.S. Steel Homestead Works, Machine Shop No. 2, Along Monongahela River, Homestead, Allegheny County, PA

  13. 12. LOWER LEVEL OF EAST BUILDING (PAINT SHOP) LOOKING SOUTH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. LOWER LEVEL OF EAST BUILDING (PAINT SHOP) LOOKING SOUTH TO RIVER NOTE; GROWN SHIP KNEES AT POSTS TO SUPPORT BEAMS. LOLLY COLUMNS ADDED TO SUPPORT SAGGING BEAM. LATRINE AND STAIRS TO STREET LEVEL CAN BE SEEN AT RIGHT. - Lowell's Boat Shop, 459 Main Street, Amesbury, Essex County, MA

  14. Putting it All Together: Has One-Stop Shopping Arrived?

    ERIC Educational Resources Information Center

    Flanagan, Patrick

    1997-01-01

    Reviews the current state of "one-stop shopping" for telecom services. Discusses regulatory obstacles; administrative problems with single billing; and resistance of telecom providers to change. Concludes that the leading one-stop shopping providers will be individual carriers who offer cost savings. (AEF)

  15. View east from Storehouse addition to Blacksmith Shop on left, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View east from Storehouse addition to Blacksmith Shop on left, Tool Room of Machine Shop on right, and directly ahead the Foundry Charging Floor with scrap pile below - East Broad Top Railroad & Coal Company, State Route 994, West of U.S. Route 522, Rockhill Furnace, Huntingdon County, PA

  16. Looking east from Storage Building with Blacksmith Shop on left, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Looking east from Storage Building with Blacksmith Shop on left, Tool Room of Machine Shop on right, with Foundry charging floor and scrap pile directly ahead - East Broad Top Railroad & Coal Company, State Route 994, West of U.S. Route 522, Rockhill Furnace, Huntingdon County, PA

  17. Authorizer Shopping: Lessons from Experience and Ideas for the Future

    ERIC Educational Resources Information Center

    Boast, Lyria; Ellison, Shonaka; Hassel, Bryan C.; Conlan, Sean; Rausch, M. Karega

    2016-01-01

    As charter school authorizers and states have increased performance expectations and grown less hesitant to close failing schools, "authorizer shopping" has emerged as a growing threat to overall charter school quality. Authorizer shopping happens when a charter school chooses or changes its authorizer specifically to avoid…

  18. Metalworking Lathe; Machine Shop Work--Intermediate: 9555.03.

    ERIC Educational Resources Information Center

    Dade County Public Schools, Miami, FL.

    The course outline has been prepared as a guide to assist the instructor to plan systematically and to present meaningful lessons to provide the training needed by the machine shop student. This is the third course of instruction in a series of machine shop work courses. The six blocks of instruction contained in this outline are designed to…

  19. 4. ROLL LATHE OF THE MAIN ROLL SHOP. THE LATHE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. ROLL LATHE OF THE MAIN ROLL SHOP. THE LATHE WAS CLOSED WITH TWO ROLLS IN PLACE, AND THE LOWER ROLL WAS TURNED TO MATCH THE UPPER ROLL. - U.S. Steel Homestead Works, Main Roll Shop, Along Monongahela River, Homestead, Allegheny County, PA

  20. Competency-Based Education Curriculum for Machine Shop. Teacher's Guide.

    ERIC Educational Resources Information Center

    Associated Educational Consultants, Inc., Pittsburgh, PA.

    This teacher's guide is designed to accompany the machine shop competency-based education curriculum for secondary students in West Virginia. It has been developed to facilitate use of the curriculum by instructors of machine shop programs. The teacher's guide contains the following material: an explanation of the curriculum and suggested usage; a…