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Sample records for peter von brentano

  1. Peter Pan.

    ERIC Educational Resources Information Center

    Storr, Catherine

    1992-01-01

    Offers a contemporary view of J. M. Barrie's life and his classic story, "Peter Pan." Suggests that "Peter Pan" does not really speak for today's children and that the time for Peter Pan's retirement has come. (PRA)

  2. Peter Pan.

    ERIC Educational Resources Information Center

    Storr, Catherine

    1992-01-01

    Offers a contemporary view of J. M. Barrie's life and his classic story, "Peter Pan." Suggests that "Peter Pan" does not really speak for today's children and that the time for Peter Pan's retirement has come. (PRA)

  3. Mathematics, experience and laboratories: Herbart's and Brentano's role in the rise of scientific psychology.

    PubMed

    Huemer, Wolfgang; Landerer, Christoph

    2010-01-01

    In this article we present and compare two early attempts to establish psychology as an independent scientific discipline that had considerable influence in central Europe: the theories of Johann Friedrich Herbart (1776-1841) and Franz Brentano (1838-1917). While both of them emphasize that psychology ought to be conceived as an empirical science, their conceptions show revealing differences. Herbart starts with metaphysical principles and aims at mathematizing psychology, whereas Brentano rejects all metaphysics and bases his method on a conception of inner perception (as opposed to inner observation) as a secondary consciousness, by means of which one gets to be aware of all of one's own conscious phenomena. Brentano's focus on inner perception brings him to deny the claim that there could be unconscious mental phenomena - a view that stands in sharp contrast to Herbart's emphasis on unconscious, "repressed" presentations as a core element of his mechanics of mind. Herbart, on the other hand, denies any role for psychological experiments, while Brentano encouraged laboratory work, thus paving the road for the more experimental work of his students like Stumpf and Meinong. By briefly tracing the fate of the schools of Herbart and Brentano, respectively, we aim to illustrate their impact on the development of psychological research, mainly in central Europe.

  4. Wernher von Braun

    NASA Image and Video Library

    1970-02-24

    In February 1970, MSFC Director Dr. von Braun was named NASA Deputy Associate Administrator for Plarning and transferred to the Agency's Headquarters in Washington D.C. Prior to his departure, Huntsvillians, along with state local dignitaries, honored his years of service to the Army and NASA with a series of events. One included unveiling a plaque in von Braun's honor. Pictured with Dr. von Braun are (left to right), his daughter Iris, wife Maria, U.S. Senator John Sparkman and Alabama Governor Albert Brewer, Dr. von Braun, son Peter, and daughter Margrit.

  5. Franz Brentano and the beginning of experimental psychology: implications for the study of psychological phenomena today.

    PubMed

    Meyer, Andreas; Hackert, Benedikt; Weger, Ulrich

    2016-12-20

    The manifestation of psychology as an academic discipline more than a 100 years ago was accompanied by a paradigm shift in our understanding of psychological phenomena-with both its light and shadow sides. On the one hand, this development allowed for a rigorous and experimentation-based approach to psychological phenomena; on the other, it led to an alienation from the experiential-or qualia-facets as the topics under inquiry were researched increasingly through third-person (e.g., behavioral or physiological) measures. At the turning point of this development stood an eminent but little known European scholar, Franz Brentano, who called for a synthesis of both third-person and first-person research methods in the study of psychological phenomena. On the occasion of his death, a hundred years ago on March 17, 1917 we wish to illustrate the historical background, introduce the reader to Brentano's approach and work and discuss its relevance for experimental psychology today.

  6. Dr. Wernher Von Braun

    NASA Technical Reports Server (NTRS)

    1999-01-01

    A camerman catches Dr. Wernher Von Braun, Director of the Marshall Space Flight Center, his son, Peter, and daughter, Martgrit, as they arrive at the employee picnic held to celebrate man's first landing on the moon 6 days earlier. In the foreground is David R. Newby, Director of Administration and Technical Services at the Marshall Space Flight Center.

  7. Remembering Peter Medway

    ERIC Educational Resources Information Center

    Hardcastle, John; Clements, Simon

    2015-01-01

    Peter Medway was an exceptionally able teacher, researcher and thinker, and his work throws light on governments, inspectors and educators. In the early 1960s, Peter met a theory which "established language as a major means of constructing our realities". Later, after teaching English in secondary schools for two decades, he reflected on…

  8. Loving Peter Pan.

    ERIC Educational Resources Information Center

    Kinkaid, James R.

    2003-01-01

    Explores the story of "Peter Pan." Considers its creation, its role on the stage, and its impact on society. Considers how "Peter Pan" is about the inability to have make-believe and the true stick together: it dramatizes an artistic failure, the failure to make the vision of the play successful. (SG)

  9. Remembering Peter Medway

    ERIC Educational Resources Information Center

    Hardcastle, John; Clements, Simon

    2015-01-01

    Peter Medway was an exceptionally able teacher, researcher and thinker, and his work throws light on governments, inspectors and educators. In the early 1960s, Peter met a theory which "established language as a major means of constructing our realities". Later, after teaching English in secondary schools for two decades, he reflected on…

  10. Loving Peter Pan.

    ERIC Educational Resources Information Center

    Kinkaid, James R.

    2003-01-01

    Explores the story of "Peter Pan." Considers its creation, its role on the stage, and its impact on society. Considers how "Peter Pan" is about the inability to have make-believe and the true stick together: it dramatizes an artistic failure, the failure to make the vision of the play successful. (SG)

  11. Obituary: Peter E. Brommer

    NASA Astrophysics Data System (ADS)

    Buschow, K. H. J.; de Boer, F. R.; Degiorgi, L.; Jochemsen, R.; Wada, H.; Oostinga, Jeroen; van Wetering, Karine

    2016-07-01

    With great sadness we inform you that Dr P.E. Brommer, editor of Physica B: Condensed Matter Physics has passed away on March 23. Peter has been on the editorial board of the journal for more than 10 years. He was very dedicated to the journal and performed his editorial work with great care and sincerity. For all of us, the opinion and judgment of Peter have always been of crucial importance. We are very grateful for what Peter has meant for the journal. We will enormously miss him.

  12. Reply to Peter Mueser.

    ERIC Educational Resources Information Center

    McCloskey, Donald N.

    1990-01-01

    Refutes Peter Mueser's criticisms of the author's position on formalistic research approaches. Restates that statistical significance is virtually useless. Claims mathematical economists take their intellectual positions from mathematics departments bringing irrelevant intellectual values into economics. (NL)

  13. Dr. Wernher Von Braun at a picnic.

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. Wernher Von Braun, director of the Marshall Space Flight Center, stakes claim to a table for the picnic celebrating man's first lunar landing. With Dr. Von Braun are his wife, Maria (seated, right), and son, Peter (back to camera). His daughter, Margrit, was also present, but is hidden from view by friends in this view.

  14. Dr. Wernher Von Braun at a picnic.

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. Wernher Von Braun, director of the Marshall Space Flight Center, stakes claim to a table for the picnic celebrating man's first lunar landing. With Dr. Von Braun are his wife, Maria (seated, right), and son, Peter (back to camera). His daughter, Margrit, was also present, but is hidden from view by friends in this view.

  15. Peter Pindar (John Wolcot).

    ERIC Educational Resources Information Center

    Vales, Robert L.

    This book is designed as an introduction to John Wolcot's works for the general reader, the college student, and the college teacher. Wolcot, whose pen name was Peter Pindar, wrote topical satire on public personalities of the eighteenth century, and his methods of criticism are the motif which guides each chapter and which unites all the satires…

  16. Peter Pindar (John Wolcot).

    ERIC Educational Resources Information Center

    Vales, Robert L.

    This book is designed as an introduction to John Wolcot's works for the general reader, the college student, and the college teacher. Wolcot, whose pen name was Peter Pindar, wrote topical satire on public personalities of the eighteenth century, and his methods of criticism are the motif which guides each chapter and which unites all the satires…

  17. Contesting Peter Newmark.

    ERIC Educational Resources Information Center

    Viaggio, Sergio

    A discussion of the theoretical and practical work of Peter Newmark on translation asserts that despite his claims to the contrary, Newmark does have a single, coherent theory of translation, that it is a wrong and didactically dangerous one, and that he nonetheless has made a substantive and welcome contribution to the development of translation…

  18. Powder diffraction in Bragg–Brentano geometry with straight linear detectors

    PubMed Central

    Kriegner, Dominik; Matěj, Zdeněk; Kužel, Radomír; Holý, Václav

    2015-01-01

    A common way of speeding up powder diffraction measurements is the use of one- or two-dimensional detectors. This usually goes hand in hand with worse resolution and asymmetric peak profiles. In this work the influence of a straight linear detector on the resolution function in the Bragg–Brentano focusing geometry is discussed. Because of the straight nature of most modern detectors geometrical defocusing occurs, which heavily influences the line shape of diffraction lines at low angles. An easy approach to limit the resolution-degrading effects is presented. The presented algorithm selects an adaptive range of channels of the linear detector at low angles, resulting in increased resolution. At higher angles the whole linear detector is used and the data collection remains fast. Using this algorithm a well behaved resolution function is obtained in the full angular range, whereas using the full linear detector the resolution function varies within one pattern, which hinders line-shape and Rietveld analysis. PMID:25844084

  19. A diffracted-beam monochromator for long linear detectors in X-ray diffractometers with Bragg-Brentano parafocusing geometry

    NASA Astrophysics Data System (ADS)

    van der Pers, N. M.; Hendrikx, R. W. A.; Delhez, R.; Böttger, A. J.

    2013-04-01

    A new diffracted-beam monochromator has been developed for Bragg-Brentano X-ray diffractometers equipped with a linear detector. The monochromator consists of a cone-shaped graphite highly oriented pyrolytic graphite crystal oriented out of the equatorial plane such that the parafocusing geometry is preserved over the whole opening angle of the linear detector. In our standard setup a maximum wavelength discrimination of 3% is achieved with an overall efficiency of 20% and a small decrease in angular resolution of only 0.02 °2θ. In principle, an energy resolution as low as 1.5% can be achieved.

  20. Interview with Peter Barnes.

    PubMed

    Barnes, Peter J

    2011-10-01

    Peter Barnes first started his career in respiratory research in the late 1970s following studies at the Universities of Oxford and Cambridge. He is currently Professor of Thoracic Medicine at the National Heart and Lung Institute, Head of Respiratory Medicine at Imperial College and Honorary Consultant Physician at the Royal Brompton Hospital. He speaks to Future Medicinal Chemistry about the molecular mechanisms currently under investigation by his group, and discusses his views on the latest therapeutic breakthroughs and the future of respiratory research.

  1. The Peter What? A Challenge to the Peter Principle

    ERIC Educational Resources Information Center

    Batten, Joe D.

    1971-01-01

    The Peter Principle" is delightful reading particularly for the obsolete or near obsolete person who wants a reassuring palliative for the expedient batch of obsolete practices for which he has opted. (Author/NL)

  2. Peter Senge on Organizational Learning.

    ERIC Educational Resources Information Center

    Newcomb, Amelia

    2003-01-01

    An extended interview with management consultant Peter Senge who proposes that rethinking traditional patterns of leadership and interaction will produce a true learning community, where improvement becomes a lifelong journey. (MLF)

  3. John von Neumann Birthday Centennial

    SciTech Connect

    Grcar, Joseph F.

    2004-11-12

    In celebration of John von Neumann's 100th birthday, a series of four lectures were presented on the evening of February 10, 2003 during the SIAM Conference on Computational Science and Engineering in San Diego. The venue was appropriate because von Neumann spent much of the later part of his life, in the 1950's, as an unofficial ambassador for computational science. He was then the only senior American scientist who had experience with the new computers (digital, electronic, and programmable) and a vision of their future importance. No doubt he would have relished the chance to attend a meeting such as this. The first speaker, William Aspray, described the ''interesting times'' during which computers were invented. His remarks were based on his history [1] of this period in von Neumann's life. We were honored to have John von Neumann's daughter, Marina von Neumann-Whitman, as our second speaker. Other accounts of von Neumann's life can be found in books by two of his colleagues [2] and [3]. Our third speaker, Peter Lax, provided both mathematical and international perspectives on John von Neumann's career. Finally, Pete Stewart spoke about von Neumann's numerical error analysis [4] in the context of later work; this talk did not lend itself to transcription, but readers may consult the historical notes in [5]. Our thanks to all the speakers for a remarkable evening. We are grateful to the DOE Applied Mathematical Sciences (AMS) program for partially supporting these lectures. Thanks are also due to SIAM and William Kolata, to our emcee, Gene Golub, to Paul Saylor for recording and editing, and to Barbara Lytle for the transcriptions. More about von Neumann's work can be learned from the recent American Mathematical Society proceedings [6].

  4. Robbing Peter to pay Paul.

    PubMed

    Briggs, P

    1979-10-05

    Cutbacks in the health service are already affecting recruitment. Employing authorities are facing the problem of reducing expenditure and this will, inevitably lead to a reappraisal of decisions to employ locums. Peter Briggs, area medical officer for Hillingdon, discusses the implications and looks at the situation in the London area.

  5. Peter & Jane: A Program Showcase

    ERIC Educational Resources Information Center

    Kalinowski, Michael

    2008-01-01

    This article features the early childhood programs at Peter & Jane Kindergarten located in Petaling Java, Malaysia. The primary purpose of the programs is to lay a strong foundation for a lifelong love of learning in each child. According to principal Patricia Teh, the activities are funded by parent fees and serve children two to six years of…

  6. Peter Cooper, the Workingman's Advocate.

    ERIC Educational Resources Information Center

    Alemanne, Nicholas

    1985-01-01

    During the 19th century, America was transformed from an agrarian to an urban-industrial society. America became divided into a nation of rich and poor. Peter Cooper assumed the role of a reformer and became the spokesman for the poor. Cooper's reform efforts and his views on unions are discussed. (RM)

  7. Peter & Jane: A Program Showcase

    ERIC Educational Resources Information Center

    Kalinowski, Michael

    2008-01-01

    This article features the early childhood programs at Peter & Jane Kindergarten located in Petaling Java, Malaysia. The primary purpose of the programs is to lay a strong foundation for a lifelong love of learning in each child. According to principal Patricia Teh, the activities are funded by parent fees and serve children two to six years of…

  8. What Would Peter Drucker Say?

    ERIC Educational Resources Information Center

    Sundre, Steven M.; Raisch, C. Daniel

    2002-01-01

    Applies observations and advice by management guru Peter F. Drucker to the role of school system leaders. Topics include the customer as king, the continually changing definition of success, effective time management, the ethical dimension of decision making, and performance-based leadership (MLF)

  9. R. S. Peters and the Periphery

    ERIC Educational Resources Information Center

    Haynes, Bruce

    2013-01-01

    Paul Hirst claimed that Richard Peters "revolutionised philosophy of education". This does not accord with my experience in the Antipodean periphery. My experience of the work of Wittgenstein, Austin and Kovesi before reading Peters and Dewey, Kuhn and Toulmin subsequently meant that Peters was a major but not revolutionary figure in my…

  10. R. S. Peters and the Periphery

    ERIC Educational Resources Information Center

    Haynes, Bruce

    2013-01-01

    Paul Hirst claimed that Richard Peters "revolutionised philosophy of education". This does not accord with my experience in the Antipodean periphery. My experience of the work of Wittgenstein, Austin and Kovesi before reading Peters and Dewey, Kuhn and Toulmin subsequently meant that Peters was a major but not revolutionary figure in my…

  11. Dr. von Braun and His Family Being Honored

    NASA Technical Reports Server (NTRS)

    1970-01-01

    Marshall Space Flight Center (MSFC) Director Dr. von Braun and his family were honored with a series of events prior to his relocation to Washington, D.C., where he was assigned duties at NASA Headquarters as Deputy Associate Administrator for Plarning. (Left to right) Dr. von Braun, wife Maria, son Peter, and daughter Margrit are shown on the steps of the Madison County Courthouse, Huntsville, Alabama.

  12. The influence of Peter Ladefoged

    NASA Astrophysics Data System (ADS)

    Stevens, Kenneth N.

    2005-09-01

    The research and publications of Peter Ladefoged and his students have been a strong influence in elevating the field of phonetics to a science, and in bringing together phonetics and phonology. I will cite some examples of how Peter's work and that of his colleagues has influenced the research of many of us at MIT and around the world, where attempts to develop unifying theories often need to undergo continuous revision based on the meticulous articulatory and acoustic data that he reports in his books and other publications. These include his descriptions of the involvement of the tongue root in vowel systems, the fricatives of Mandarin Chinese, the inventory of places of articulation he catalogs in the languages of the world, and the many uses of laryngeal states in providing phonological contrasts. [Supported in part by grants from NIDCD.

  13. Short stature, brachydactyly, and Peters' anomaly (Peters'-plus syndrome): confirmation of autosomal recessive inheritance.

    PubMed Central

    de Almeida, J C; Reis, D F; Llerena Júnior, J; Barbosa Neto, J; Pontes, R L; Middleton, S; Telles, L F

    1991-01-01

    Two sibs with a phenotype characterised by short stature, brachydactyly, and ocular anomalies (Peters' anomaly) are reported (Peters'-plus syndrome). The consanguinity is in agreement with the proposed autosomal recessive inheritance. Images PMID:1856836

  14. Was Peters Nearly Right about Education?

    ERIC Educational Resources Information Center

    Barrow, Robin

    2009-01-01

    Richard Peters pioneered a form of philosophical analysis in relation to educational discourse that was criticised by some at the time and is today somewhat out of fashion. This paper argues that much of the objection to Peters' methodology is based on a misunderstanding of what it does and does not involve, that consequently philosophical…

  15. Peter Pan: The Text and the Myth.

    ERIC Educational Resources Information Center

    Hollindale, Peter

    1993-01-01

    Shows how the critical reception of J. M. Barrie's "Peter Pan" has varied widely since its publication. Describes the mythical qualities of the Peter Pan character and gives reasons why the story is still popular with children and why it should continue to be taught and read. (HB)

  16. A Hundred Years of Peter Pan

    ERIC Educational Resources Information Center

    Hollindale, Peter

    2005-01-01

    The centenary of the first performance of J. M. Barrie's Peter Pan was celebrated in December 2004. Taking account of the various events in Britain to mark the occasion--newspaper articles, radio and television programmes, retrospects in the original theatre--this article examines the status and popularity of Peter Pan after a hundred years. The…

  17. Was Peters Nearly Right about Education?

    ERIC Educational Resources Information Center

    Barrow, Robin

    2009-01-01

    Richard Peters pioneered a form of philosophical analysis in relation to educational discourse that was criticised by some at the time and is today somewhat out of fashion. This paper argues that much of the objection to Peters' methodology is based on a misunderstanding of what it does and does not involve, that consequently philosophical…

  18. Peter H. Rossi: Formative for Program Evaluation

    ERIC Educational Resources Information Center

    Lipsey, Mark W.

    2007-01-01

    This article discusses the significant contributions of Peter H. Rossi to the field of program evaluation. It was the publication of "Evaluation: A Systematic Approach" by Peter Rossi, Howard Freeman, and Sonia Rosenbaum in 1979 that most emphatically marked the point at which program evaluation had clearly consolidated as a distinct field of…

  19. A Hundred Years of Peter Pan

    ERIC Educational Resources Information Center

    Hollindale, Peter

    2005-01-01

    The centenary of the first performance of J. M. Barrie's Peter Pan was celebrated in December 2004. Taking account of the various events in Britain to mark the occasion--newspaper articles, radio and television programmes, retrospects in the original theatre--this article examines the status and popularity of Peter Pan after a hundred years. The…

  20. Peter Pan: The Text and the Myth.

    ERIC Educational Resources Information Center

    Hollindale, Peter

    1993-01-01

    Shows how the critical reception of J. M. Barrie's "Peter Pan" has varied widely since its publication. Describes the mythical qualities of the Peter Pan character and gives reasons why the story is still popular with children and why it should continue to be taught and read. (HB)

  1. Reflections on the Gall-Peters Projection.

    ERIC Educational Resources Information Center

    Robinson, Arthur H.

    1987-01-01

    Explains the cartographic qualities of rectangular world maps and compares the merits of various projections such as the Mercator and the recently-created Gall-Peters. States that the Gall-Peters projection does not provide a reasonable base for a general world map; that no rectangular projection does. (JDH)

  2. Pearn Peter Niiler (1937-2010)

    NASA Astrophysics Data System (ADS)

    Schmitz, William J., Jr.; Large, William G.

    2011-05-01

    Peter Niiler, great friend, valued colleague, and AGU Fellow since 1986, will be remembered for his scientific achievements and as one of the most colorful physical oceanographers of his generation. Indeed, the Tropic Heat experiment's colors of mauve on pink, complete with Peter's matching ensemble, remain a vivid memory of that otherwise orthodox 1980s program championed by Peter to target equatorial Pacific mixing. Peter always sought understanding: to get things right for the right reason. Therefore, he held a healthy skepticism of numerical modeling and remote sensing, while utilizing both satellites and his own brand of diagnostic modeling. Peter's science motives were noble and would lead him to fight the good fight when necessary, especially when advocating his views on the Gulf Stream path, trapped inertial currents, heat and vorticity balances, and other subjects evoking his passion.

  3. Peter Nathan (1935-2016).

    PubMed

    Fowles, Don

    2016-12-01

    Presents an obituary for Peter Nathan who died suddenly on May 8, 2016, in Iowa City, Iowa. Nathan was an outstanding clinical scientist who's pioneering research confirming the effectiveness of psychological interventions to treat alcoholism and substance abuse set off an explosion of research and clinical applications over the ensuing decades. He made seminal contributions to diagnostic decision making, syndromal assessment, and science-based treatments of psychopathology. He helped found the field of social and behavioral science of addiction. His research was supported by millions of dollars in grants from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), as well as from other organizations. He authored or coauthored nearly 20 books, including four editions of the enormously influential A Guide to Treatments that Work, and hundreds of articles in scholarly journals. (PsycINFO Database Record

  4. Peters anomaly: review of the literature.

    PubMed

    Bhandari, Ramanath; Ferri, Sara; Whittaker, Beatrice; Liu, Margaret; Lazzaro, Douglas R

    2011-08-01

    Peters anomaly is a rare dramatic finding at birth and can be associated with other systemic malformations. We performed a literature review of multiple case reports and case series to better define the common characteristics and unusual findings associated with Peters anomaly. A representative case is discussed followed by a literature review of multiple case reports and case series. The literature search was conducted for the years 1969 to 2009. Cases and case series were included in the review of published English ophthalmic literature. Cases were excluded if no information was reported on ocular and systemic malformations or if no information was reported on surgical interventions or outcomes. In addition, if cases did not report laterality of the lesion, they were excluded from the review. Fifty-eight cases were found that fit the above criteria, and the relevant cases were reviewed to better characterize the systemic malformations, interventions, and outcomes associated with Peters anomaly reported in the literature. Fifty-eight cases of Peters anomaly were reviewed. Of those cases reporting sex, 56% were men and 44% of cases were women. In terms of laterality, 67.2% of cases were bilateral versus 32.8% of cases that were unilateral. Moreover, bilateral cases of Peters anomaly were associated with a higher rate of systemic malformations (71.8%) versus unilateral Peters anomaly (36.8%). This difference was significant (P < 0.03 by Fischer exact test). In the 15 eyes where results of penetrating keratoplasty were reported, the overall success rate was 53%. However, the success rate was significantly higher in patients with Peters anomaly type I (87.5%), as opposed to those patients with Peters anomaly type II (14.2%) (P < 0.02 by Fischer exact test). The clinical features, epidemiology, genetics, complications, and treatments of Peters anomaly are presented. Cornea specialists who care for pediatric patients should be aware of the common and uncommon

  5. von Willebrand Disease

    MedlinePlus

    ... from the NHLBI on Twitter. What Is Von Willebrand Disease? Von Willebrand disease (VWD) is a bleeding disorder. ... while hemophilia mainly affects males. Types of von Willebrand Disease The three major types of VWD are called ...

  6. Peter Frampton Talks to Station Crew

    NASA Image and Video Library

    Rocker Peter Frampton and his band are introduced by astronaut Ron Garan to Commander Mike Fossum and Flight Engineers Satoshi Furukawa and Sergei Volkov aboard the International Space Station duri...

  7. Autonomy in R. S. Peters' Educational Theory

    ERIC Educational Resources Information Center

    Cuypers, Stefaan E.

    2009-01-01

    Autonomy is, among other things, an actual psychological condition, a capacity that can be developed, and an educational ideal. This paper contextualises, analyses, criticises and extends the theory of Richard S. Peters on these three aspects of autonomy.

  8. Genetics Home Reference: Peters plus syndrome

    MedlinePlus

    ... as walking and speech, are delayed in most children with Peters plus syndrome . Most affected individuals also have intellectual disability that can range from mild to severe, although some have normal intelligence. The severity of physical features does not predict ...

  9. John Peter Zenger, Battler for Freedom

    ERIC Educational Resources Information Center

    Wallerstein, Gerry

    1974-01-01

    Examines the freedom of the press precedent set by the John Peter Zenger case in 1743 and considers its application to such current events as the jailing of reporters for not disclosing news sources. (RB)

  10. Peter Gabriel Talks With Space Station Crew

    NASA Image and Video Library

    Singer-songwriter Peter Gabriel and family visit Mission Control Houston and talk with Expedition 33 Commander Kevin Ford and Flight Engineers Tom Marshburn and Chris Hadfield aboard the Internatio...

  11. John Peter Zenger, Battler for Freedom

    ERIC Educational Resources Information Center

    Wallerstein, Gerry

    1974-01-01

    Examines the freedom of the press precedent set by the John Peter Zenger case in 1743 and considers its application to such current events as the jailing of reporters for not disclosing news sources. (RB)

  12. Whole exome sequence analysis of Peters anomaly.

    PubMed

    Weh, Eric; Reis, Linda M; Happ, Hannah C; Levin, Alex V; Wheeler, Patricia G; David, Karen L; Carney, Erin; Angle, Brad; Hauser, Natalie; Semina, Elena V

    2014-12-01

    Peters anomaly is a rare form of anterior segment ocular dysgenesis, which can also be associated with additional systemic defects. At this time, the majority of cases of Peters anomaly lack a genetic diagnosis. We performed whole exome sequencing of 27 patients with syndromic or isolated Peters anomaly to search for pathogenic mutations in currently known ocular genes. Among the eight previously recognized Peters anomaly genes, we identified a de novo missense mutation in PAX6, c.155G>A, p.(Cys52Tyr), in one patient. Analysis of 691 additional genes currently associated with a different ocular phenotype identified a heterozygous splicing mutation c.1025+2T>A in TFAP2A, a de novo heterozygous nonsense mutation c.715C>T, p.(Gln239*) in HCCS, a hemizygous mutation c.385G>A, p.(Glu129Lys) in NDP, a hemizygous mutation c.3446C>T, p.(Pro1149Leu) in FLNA, and compound heterozygous mutations c.1422T>A, p.(Tyr474*) and c.2544G>A, p.(Met848Ile) in SLC4A11; all mutations, except for the FLNA and SLC4A11 c.2544G>A alleles, are novel. This is the first study to use whole exome sequencing to discern the genetic etiology of a large cohort of patients with syndromic or isolated Peters anomaly. We report five new genes associated with this condition and suggest screening of TFAP2A and FLNA in patients with Peters anomaly and relevant syndromic features and HCCS, NDP and SLC4A11 in patients with isolated Peters anomaly.

  13. Whole exome sequence analysis of Peters anomaly

    PubMed Central

    Weh, Eric; Reis, Linda M.; Happ, Hannah C.; Levin, Alex V.; Wheeler, Patricia G.; David, Karen L.; Carney, Erin; Angle, Brad; Hauser, Natalie

    2015-01-01

    Peters anomaly is a rare form of anterior segment ocular dysgenesis, which can also be associated with additional systemic defects. At this time, the majority of cases of Peters anomaly lack a genetic diagnosis. We performed whole exome sequencing of 27 patients with syndromic or isolated Peters anomaly to search for pathogenic mutations in currently known ocular genes. Among the eight previously recognized Peters anomaly genes, we identified a de novo missense mutation in PAX6, c.155G>A, p.(Cys52Tyr), in one patient. Analysis of 691 additional genes currently associated with a different ocular phenotype identified a heterozygous splicing mutation c.1025+2T>A in TFAP2A, a de novo heterozygous nonsense mutation c.715C>T, p.(Gln239*) in HCCS, a hemizygous mutation c.385G>A, p.(Glu129Lys) in NDP, a hemizygous mutation c.3446C>T, p.(Pro1149Leu) in FLNA, and compound heterozygous mutations c.1422T>A, p.(Tyr474*) and c.2544G>A, p.(Met848Ile) in SLC4A11; all mutations, except for the FLNA and SLC4A11 c.2544G>A alleles, are novel. This is the frst study to use whole exome sequencing to discern the genetic etiology of a large cohort of patients with syndromic or isolated Peters anomaly. We report five new genes associated with this condition and suggest screening of TFAP2A and FLNA in patients with Peters anomaly and relevant syndromic features and HCCS, NDP and SLC4A11 in patients with isolated Peters anomaly. PMID:25182519

  14. The Statue of Liberty Peter Max Style!

    ERIC Educational Resources Information Center

    Cunningham, Kathy

    2012-01-01

    The author's school is only 30 minutes from New York City, so every year when second-graders study towns and cities, the students do a project based on New York City landmarks. This year was the Statue of Liberty. The author introduced Peter Max's famous Pop art to her students, and explained that, as the art world kept changing, artists decided…

  15. Reading R. S. Peters on Education Today

    ERIC Educational Resources Information Center

    Cuypers, Stefaan E.; Martin, Christopher

    2009-01-01

    This introduction to this special issue offers an overview of R. S. Peters' seminal role in the development of modern philosophy of education, acknowledging the originality and range of his work, and indicating his continuing importance to the field. It explains the structure and organisation of the collection and provides a rationale for this…

  16. R. S. Peters: The Reasonableness of Ethics

    ERIC Educational Resources Information Center

    Haynes, Felicity

    2013-01-01

    This article will begin by examining the extent to which R. S. Peters merited the charge of analytic philosopher. His background in social psychology allowed him to become more pragmatic and grounded in social conventions and ordinary language than the analytic philosophers associated with empiricism, and his gradual shift from requiring internal…

  17. The Statue of Liberty Peter Max Style!

    ERIC Educational Resources Information Center

    Cunningham, Kathy

    2012-01-01

    The author's school is only 30 minutes from New York City, so every year when second-graders study towns and cities, the students do a project based on New York City landmarks. This year was the Statue of Liberty. The author introduced Peter Max's famous Pop art to her students, and explained that, as the art world kept changing, artists decided…

  18. The Peter Principle: A Theory of Decline

    ERIC Educational Resources Information Center

    Lazear, Edward P.

    2004-01-01

    Some have observed that individuals perform worse after being promoted. The Peter principle, which states that people are promoted to their level of incompetence, suggests that something is fundamentally misaligned in the promotion process. This view is unnecessary and inconsistent with the data. Below, it is argued that ability appears lower…

  19. R. S. Peters: The Reasonableness of Ethics

    ERIC Educational Resources Information Center

    Haynes, Felicity

    2013-01-01

    This article will begin by examining the extent to which R. S. Peters merited the charge of analytic philosopher. His background in social psychology allowed him to become more pragmatic and grounded in social conventions and ordinary language than the analytic philosophers associated with empiricism, and his gradual shift from requiring internal…

  20. Peter Koch: wizard of wood use

    Treesearch

    M.E. Lora

    1978-01-01

    Like his pioneer forefathers, Peter Koch sees opportunity where others see obstacles. And his vision is helping to reshape the wood industry. Since 1963 Koch has directed research on processing southern woods for the U.S. Forest Service's Southern Forest Experiment Station in Pineville, Louisiana. In that time, he has invented six revolutionary machines, developed...

  1. Peter Waterman and T-Matrix Methods

    NASA Technical Reports Server (NTRS)

    Mishchenko, M. I.; Martin, P.A.

    2013-01-01

    This paper summarizes the scientific legacy of Peter C. Waterman (1928-2012) who introduced concepts and theoretical techniques that have had a major impact on the fields of scattering by particles and particle groups, optical particletcharacterization, radiative transfer, and remote sensing. A biographical sketch is also included.

  2. Reading R. S. Peters on Education Today

    ERIC Educational Resources Information Center

    Cuypers, Stefaan E.; Martin, Christopher

    2009-01-01

    This introduction to this special issue offers an overview of R. S. Peters' seminal role in the development of modern philosophy of education, acknowledging the originality and range of his work, and indicating his continuing importance to the field. It explains the structure and organisation of the collection and provides a rationale for this…

  3. Obituary: Peter Robert Wilson, 1929-2007

    NASA Astrophysics Data System (ADS)

    Snodgrass, Herschel B.

    2009-01-01

    It is with great sadness that I report the passing of Peter Robert Wilson, a well-known and well-loved figure in the solar physics community. Peter was on the faculty of the Department of Applied Mathematics at the University of Sydney for 39 years, and Chair of the department for 24 of these years. He was the author or co-author of more than 80 scientific research papers and a book, Solar and Stellar Activity Cycles (1994), published by Cambridge University Press. He died suddenly of a heart attack, at his home in Glebe, Australia, in the early morning of 11 November 2007. Peter was an organizer of, and participant in, many international conferences and workshops. He traveled extensively, holding visiting appointments at the University of Colorado (JILA), at Cambridge University, at the College de France (Paris), and at the California Institute of Technology [CalTech]. Most of his work was in the field of solar physics, but he also did some work on the philosophy of science and on tides. Peter came from a line of mathematicians. His father, Robert Wilson, immigrated to Australia from Glasgow in 1911, and became a mathematics teacher at Scotch College, a private school in Melbourne. There his name was changed to 'Bill' because 'Bob' was already taken." Peter's enjoyment of this story as characteristic of Australian academia (as any fan of Monty Python would understand) is indicative of his infectious sense of humor. In a similar vein, he claimed ancestry traced back to the eighteenth-century Scottish mathematician Alexander Wilson, Professor of Astronomy at the University of Glasgow. That Wilson is famous in the solar physics community for his discovery, known as the "Wilson Effect," of the photospheric depressions associated with sunspots. Peter himself could not resist writing a paper on this subject, and was delighted when the bait was taken by some less-informed colleagues who chided him for "naming an effect after himself." "Bill" Wilson married Naomi

  4. Wernher von Braun

    NASA Image and Video Library

    1967-06-06

    Throughout his career, Dr. von Braun received numerous awards for his contributions to space flight. On June 6, 1967, Dr. Fred L. Whipple, Director of the Smithsonian Astrophysical Observatory, presented Dr. von Braun with the Smithsonian Langley Medal.

  5. Wernher von Braun

    NASA Image and Video Library

    1945-04-01

    Dr. Wernher von Braun surrenders to U.S. Army Counterintelligence persornel of the 44th Infantry Division in Ruette, Bavaria on May 2, 1945. Left to right are Charles Stewart, CIC agent; Dr. Herbert Axster; Dieter Huzel; Dr. von Braun (arm in cast); Magnus von Braun (brother); and Hans Lindenberg.

  6. Peter Waterman and his scientific legacy

    NASA Technical Reports Server (NTRS)

    Mishchenko, Michael I.; Kahnert, Michael; Mackowski, Daniel W.; Wriedt, Thomas

    2013-01-01

    Peter C. Waterman, a giant figure in the theory of electromagnetic, acoustic, and elastic wave scattering, passed away on 3 June, 2012. In view of his fundamental contributions, which to a large degree have guided the progress of these disciplines over the past five decades and affected profoundly the multifaceted research published in the Journal of Quantitative Spectroscopy and Radiative Transfer (JQSRT), we felt that it would be appropriate to solicit papers for a special issue of JQSRT commemorating Peter Waterman's scientific legacy. This initiative was endorsed by the JQSRT management and has resulted in a representative collection of high-quality papers which have undergone the same peer scrutiny as any paper submitted to JQSRT.

  7. Peter Waterman and his scientific legacy

    NASA Technical Reports Server (NTRS)

    Mishchenko, Michael I.; Kahnert, Michael; Mackowski, Daniel W.; Wriedt, Thomas

    2013-01-01

    Peter C. Waterman, a giant figure in the theory of electromagnetic, acoustic, and elastic wave scattering, passed away on 3 June, 2012. In view of his fundamental contributions, which to a large degree have guided the progress of these disciplines over the past five decades and affected profoundly the multifaceted research published in the Journal of Quantitative Spectroscopy and Radiative Transfer (JQSRT), we felt that it would be appropriate to solicit papers for a special issue of JQSRT commemorating Peter Waterman's scientific legacy. This initiative was endorsed by the JQSRT management and has resulted in a representative collection of high-quality papers which have undergone the same peer scrutiny as any paper submitted to JQSRT.

  8. [Long-term prognosis of Peters anomaly].

    PubMed

    Reichl, S; Böhringer, D; Richter, O; Lagrèze, W; Reinhard, T

    2017-05-08

    Peters anomaly normally presents in early childhood. Common features are central corneal opacities and dysgeneses of the anterior eye segment. Early surgery is commonly warranted to prevent deep amblyopia or because of severe glaucoma. We herein present the clinical outcomes of all patients treated in the Eye Center of the Albert Ludwigs University of Freiburg since 2005. Emphasis is placed on the Peters subtype. Data were collected retrospectively by means of chart review. Kaplan-Meier analyses were used to estimate visual prognosis, the indication for keratoplasty, and the incidence of retinal detachment. A total of 23 patients were identified. Subtype distribution was 40% type 1, 50% type 2, and 10% Peters plus syndrome. Ten patients were female (45%). Mean age at first presentation was 5 years; mean follow-up period censored in terms of eyeball preservation was 2 years (0 months-8 years). At mean follow-up, 40.5% of all patients had undergone at least one keratoplasty (up to six per eye); 43% had undergone glaucoma surgery (cylophotocoagulation, trabeculectomy, implants) at this time. Important complications were retinal detachment (31%) and phthisis bulbi (15%). After 4 years, visual acuity in the better eye was at most 0.05 in every second patient. Prognosis of visual acuity in Peters anomaly is poor. It is generally not possible to restore visual function in the long run, i. e., reading-grade visual acuity is rarely achieved. Surgical interventions are associated with a high risk of severe complications. Therefore, the young patients should be connected to institutions for visually impaired persons at an early stage.

  9. Peter V.Hobbs (1936-2005)

    NASA Astrophysics Data System (ADS)

    Wallace, John M.

    Peter Hobbs, a professor in the Department of Atmospheric Sciences at the University of Washington in Seattle, died of pancreatic cancer on 25 July 2005.Born in 1936, Hobbs experienced what he described as “a wild, adventurous youth on the streets of postwar London.” He engaged in competitive swimming and at age 13 held the title of Junior Boxing Champion of the County of Surrey.

  10. Peter Ladefoged and phonetics in the field

    NASA Astrophysics Data System (ADS)

    Maddieson, Ian

    2005-09-01

    Among many distinctive contributions to phonetics by Peter Ladefoged is an insistence on the immense diversity of phonetic phenomena in the languages of the world, particularly at the segmental level. Because of this Peter has maintained a flexible approach to any scheme of classification or description, adapting to both new approaches and new data. Perhaps more than any other phonetician he has expected to find surprises, and has gone to far corners of the world in search of them. His ground-breaking Phonetic Study of West African Languages from 1964 laid out a template for synthesizing a large mass of data which is echoed in later works such as Preliminaries to Linguistic Phonetics and Sounds of the World's Languages. His widely used Course in Phonetics and other textbooks have shown generations of students the richness of spoken sound. But not only novel research results have marked Peter's contributions to this aspect of phonetics; equally significant are his methodological innovations in taking experimental techniques to the field. Some of the most salient steps along both these paths will be reviewed from personal and professional perspectives.

  11. Wernher von Braun

    NASA Image and Video Library

    1970-02-24

    In 1970 Marshall Space Flight Center (MSFC) Director Dr. Wernher von Braun (right) was reassigned to NASA Headquarters to serve as Deputy Associate Administrator for Plarning. Prior to his transfer, Dr. von Braun was honored for his career in Huntsville, Alabama, with the celebration of "Wernher von Braun Day." Among those participating were Alabama Governor Albert Brewer (left) and Alabama Senator John Sparkman (center). (Courtesy of Huntsville/Madison County Public library)

  12. Wernher von Braun

    NASA Image and Video Library

    1954-01-01

    Marshall Center Director Dr. Wernher Von Braun is pictured with Walt Disney during a visit to the Marshall Space Flight Center in 1954. In the 1950s, Dr. Von Braun while working in California on the Saturn project, also worked with Disney studios as a technical director in making three films about Space Exploration for television. Disney's tour of Marshall in 1965 was Von Braun's hope for a renewed public interest in the future of the Space Program at NASA.

  13. Theodore von Karman

    NASA Technical Reports Server (NTRS)

    1926-01-01

    Theodore von Karman. NACA: In the eyes of most aeronautical experts, the overall record of Max Munk in aerodynamic research falls short of that achieved by fellow immigrant Theodore von Karman (the short man in the double breasted coat in the middle), shown here visiting Langley in December 1926. People in the photo include Max Munk, aerodynamic researcher; Theodore von Karman; George Lewis, director of research; Henry Reid, engineer in charge; Fred Weick, PRT head; Paul Hemke; Elliott Reid, future Stanford University Professor.

  14. PETERS MOUNTAIN WILDERNESS STUDY AREA, VIRGINIA.

    USGS Publications Warehouse

    Lesure, Frank G.; Williams, Bradford B.

    1984-01-01

    A mineral-resource survey of the Peters Mountain Wilderness Study Area, Virginia concluded that the area contains steeply dipping and faulted clastic sedimentary rocks of Paleozoic age that have a substantiated iron resource potential and abundant rock suitable for construction materials. The area has an estimated 340 million long tons of inferred low-grade iron resources in hematitic sandstone that may average as much as 20 percent iron, or 68 million long tons of contained iron. Structural conditions favorable for hydrocarbon accumulation appear to be absent beneath the area.

  15. Rheologie von Beschichtungen

    NASA Astrophysics Data System (ADS)

    Schäffler, Michael

    Die Rheologie beschreibt die Fließ- und Deformationseigenschaften von Materialien. Der Begriff Rheologie ist aus dem Griechischen abgeleitet: rhein - fließen. Erst im Jahre 1930 entwickelte E.C. Bingham und M. Reiner in Easton (USA) die Rheologie zu einer eigenständigen Wissenschaft. Aber bereits seit dem 17. Jahrhundert wurden wesentliche Einzelbeiträge zu Fließphänomenen veröffentlich, so z.B. 1676 von R. Hooke (Hookesches Gesetz) und 1687 von I. Newton (Newtonsches Gesetz). Die Rheologie hat sich bis heute immer mehr zu einer interdisziplinären Wissenschaft entwickelt, die die mechanischen Eigenschaften von Materialien charakterisiert.

  16. Wernher von Braun

    NASA Image and Video Library

    1959-01-01

    This photograph of Dr. von Braun, shown here to the left of General Bruce Medaris, was taken in the fall of 1959, immediately prior to Medaris' retirement from the Army. At the time, von Braun and his associates worked for the Army Ballistics Missile Agency in Huntsville, Alabama. Those in the photograph have been identified as Ernst Stuhlinger, Frederick von Saurma, Fritz Mueller, Hermarn Weidner, E.W. Neubert (partially hidden), W.A. Mrazek, Karl Heimburg, Arthur Rudolph, Otto Hoberg, von Braun, Oswald Lange, Medaris, Helmut Hoelzer, Hans Maus, E.D. Geissler, Hans Heuter, and George Constan.

  17. Wernher von Braun

    NASA Image and Video Library

    1960-01-01

    Dr. Wernher von Braun served as Marshall Space Flight Center's first director from July 1, 1960 until January 27, 1970, when he was appointed NASA Deputy Associate Administrator for Plarning. Following World War II, Dr. von Braun and his German colleagues arrived in the United States under Project Paperclip to continue their rocket development work. In 1950, von Braun and his rocket team were transferred from Ft. Bliss, Texas to Huntsville, Alabama to work for the Army's rocket program at Redstone Arsenal and later, NASA's Marshall Space Flight Center. Under von Braun's leadership, Marshall developed the Saturn V launch vehicle which took Apollo astronauts to the moon.

  18. Living with von Willebrand Disease

    MedlinePlus

    ... from the NHLBI on Twitter. Living With von Willebrand Disease If you have von Willebrand disease (VWD), you ... that they get tested too. Pregnancy and von Willebrand Disease Pregnancy can be a challenge for women who ...

  19. Wernher von Braun

    NASA Image and Video Library

    1959-01-01

    Five of the seven original astronauts are seen with Dr. von Braun inspecting the Mercury-Redstone hardware in the Fabrication Laboratory of Army Ballistic Missile Agency (ABMA) in 1959. Left to right: Astronauts Walter Schirra, Alan Shepard, John Glenn, Scott Carpenter, Gordon Cooper, and Dr. von Braun.

  20. Wernher von Braun

    NASA Image and Video Library

    1963-03-01

    This is a portrait of Maria von Braun, wife of the famous Marshall Space Flight Center (MSFC) director Wernher von Braun. Her husband, Wernher, who led America to the Moon, served as MSFC’s first director from July 1, 1960 until January 27, 1970.

  1. Wernher von Braun

    NASA Image and Video Library

    1967-11-14

    Astronaut L. Gordon Cooper checks the neck ring of a space suit worn by Marshall Space Flight Center (MSFC) Director, Dr. von Braun before he submerges into the water of the MSFC Neutral Buoyancy Simulator (NBS). Wearing a pressurized suit and weighted to a neutrally buoyant condition, Dr. von Braun was able to perform tasks underwater which simulated weightless conditions found in space.

  2. Wernher von Braun

    NASA Image and Video Library

    1967-11-14

    Marshall Space Flight Center (MSFC) Director, Dr. von Braun, submerges after spending some time under water in the MSFC Neutral Buoyancy Simulator (NBS). Weighted to a neutrally buoyant condition, Dr. von Braun was able to perform tasks underwater which simulated weightless conditions found in space.

  3. Wernher von Braun

    NASA Image and Video Library

    1967-11-14

    Marshall Space Flight Center (MSFC) Director, Dr. von Braun, is shown leaving the suiting-up van wearing a pressure suit prepared for a tryout in the MSFC Neutral Buoyancy Simulator (NBS). Weighted to a neutrally buoyant condition, Dr. von Braun was able to perform tasks underwater which simulated weightless conditions found in space.

  4. Wernher von Braun

    NASA Image and Video Library

    1967-11-14

    Marshall Space Flight Center (MSFC) Director, Dr. von Braun, is shown fitted with suit and diving equipment as he prepares for a tryout in the MSFC Neutral Buoyancy Simulator (NBS). Weighted to a neutrally buoyant condition, Dr. von Braun was able to perform tasks underwater which simulated weightless conditions found in space.

  5. Wernher von Braun

    NASA Image and Video Library

    1968-01-22

    Dr. Wernher Von Braun, stands in front of a Saturn IB Launch Vehicle at Kennedy Space Center (KSC). Dr. Von Braun was Marshall's first Center Director (1960-1970). Under his leadership Marshall was responsible for the development of the Saturn rockets, the Skylab project and getting the United States into Space and landing on the moon with the Apollo missions.

  6. Wernher von Braun

    NASA Image and Video Library

    1970-02-24

    Dr. von Braun was noted for his public speeches and presentations. In this photograph, Dr. von Braun gave a speech during a series of events to honor him prior to his relocation to Washington where he was assigned to his new duty as NASA's Deputy Associate Administrator for Plarning at NASA Headquarters.

  7. Dr. Wernher Von Braun

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. Wernher Von Braun (left) and Fred W. Kelley examine a ST-100 Stellar Instrument Platform in the astrionics lab. Dr. Von Braun, then deputy associate administrator for planning, NASA, was visiting on the anniversary of the establishment of the Marshall Space Flight Center.

  8. FOREWORD: Peter Clay Eklund: a scientific biography Peter Clay Eklund: a scientific biography

    NASA Astrophysics Data System (ADS)

    Cole, Milton W.; Crespi, Vincent H.; Dresselhaus, Gene F.; Dresselhaus, Mildred S.; Mahan, Gerald D.; Sofo, Jorge O.

    2010-08-01

    Peter Eklund grew up in Southern California and attended the University of California at Berkeley, majoring in physics. After working for one year at the Lockheed Missile and Space Company in Sunnyvale, California, he left to pursue graduate studies at Purdue University. There he carried out PhD research in strongly correlated electron and phonon systems under the supervision of J M Honig and L L van Zandt. Peter joined the group of Millie and Gene Dresselhaus at MIT in 1974 as a Postdoctoral Fellow after one year as an instructor at the University of Kentucky. At MIT, he continued work on strongly correlated systems in collaboration with Professor David Adler (who had an adjoining office), but for the most part he got excited about sp2 carbon systems and graphite intercalation compounds, a new research direction which the Dresselhaus group had started one year before Peter's arrival at MIT. Over the next 35 years Peter, Millie and Gene co-authored over 50 research articles, several review articles, and a big nine-hundred-and-fifty page book. In 1974, they saw graphite intercalation compounds as a long-neglected research direction of great promise. They studied these new materials together over the next 16 years, focusing on their optical spectroscopy. Their pioneering vibrational spectroscopy studies provided a means to characterize the fundamental properties of carbon materials. Optical spectroscopy became a centerpiece in the research portfolios of all three, both when they were together at MIT and after Peter left for the University of Kentucky in 1977 to start his independent career as an Assistant Professor of Physics. Peter became a full Professor at Kentucky in 1986. He continued to work with Millie and Gene and also acquired an ever-expanding network of students, postdocs and collaborators. As each new carbon nanostructure emerged—graphite intercalation compounds, fullerenes, carbon nanotubes, and most recently graphene—Peter was at the cutting edge

  9. Wernher von Braun

    NASA Image and Video Library

    2004-04-15

    Dr. von Braun is looking out from a 10th floor window of building 4200 at the Marshall Space Flight Center (MSFC). He was the first Center Director and served as the Director from July 1960 through February 1970. Following World War II, Dr. von Braun and his German colleagues arrived in the United States under the Project Paperclip (American acquisition of German rocket experts) to continue their rocket development work. In 1950, von Braun and his German Rocket Team (also called the Peenemuende Team) were transferred from Ft. Bliss, Texas to Huntsville, Alabama to work for the Army's rocket program at Redstone Arsenal and later, NASA's Marshall Space Flight Center (MSFC). Under Dr. von Braun's leadership, MSFC developed the Saturn V launch vehicle, which placed the first men, two American astronauts, on the Moon. Wernher von Braun's life was dedicated to expanding man's knowledge through the exploration of space.

  10. Dr. Wernher von Braun

    NASA Technical Reports Server (NTRS)

    2004-01-01

    Dr. von Braun is looking out from a 10th floor window of building 4200 at the Marshall Space Flight Center (MSFC). He was the first Center Director and served as the Director from July 1960 through February 1970. Following World War II, Dr. von Braun and his German colleagues arrived in the United States under the Project Paperclip (American acquisition of German rocket experts) to continue their rocket development work. In 1950, von Braun and his German Rocket Team (also called the Peenemuende Team) were transferred from Ft. Bliss, Texas to Huntsville, Alabama to work for the Army's rocket program at Redstone Arsenal and later, NASA's Marshall Space Flight Center (MSFC). Under Dr. von Braun's leadership, MSFC developed the Saturn V launch vehicle, which placed the first men, two American astronauts, on the Moon. Wernher von Braun's life was dedicated to expanding man's knowledge through the exploration of space.

  11. Dr. Wernher von Braun

    NASA Technical Reports Server (NTRS)

    2004-01-01

    Dr. von Braun is looking out from a 10th floor window of building 4200 at the Marshall Space Flight Center (MSFC). He was the first Center Director and served as the Director from July 1960 through February 1970. Following World War II, Dr. von Braun and his German colleagues arrived in the United States under the Project Paperclip (American acquisition of German rocket experts) to continue their rocket development work. In 1950, von Braun and his German Rocket Team (also called the Peenemuende Team) were transferred from Ft. Bliss, Texas to Huntsville, Alabama to work for the Army's rocket program at Redstone Arsenal and later, NASA's Marshall Space Flight Center (MSFC). Under Dr. von Braun's leadership, MSFC developed the Saturn V launch vehicle, which placed the first men, two American astronauts, on the Moon. Wernher von Braun's life was dedicated to expanding man's knowledge through the exploration of space.

  12. Wernher von Braun

    NASA Image and Video Library

    1977-06-16

    Dr. Wernher von Braun served as Marshall Space Flight Center's first director from July 1, 1960 until January 27, 1970, when he was appointed NASA Deputy Associate Administrator for Planning. Following World War II, Dr. von Braun and his German colleagues arrived in the United States under Project Paper Clip to continue their rocket development work. In 1950, von Braun and his rocket team were transferred from Ft. Bliss, Texas to Huntsville, Alabama to work for the Army's rocket program at Redstone Arsenal and later, NASA's Marshall Space Flight Center. Under von Braun's leadership, Marshall developed the Saturn V launch vehicle which took Apollo astronauts to the moon. Dr. von Braun died in Alexandria, Va., on June 16, 1977, seven years after his NASA appointment. This photo was taken at the site where he was laid to rest.

  13. Theories of Power, Poverty, and Law: In Commemoration of the Contributions of Peter Bachrach--Power, Law, and Final Thoughts: The Contributions of Peter Bachrach

    ERIC Educational Resources Information Center

    Schneider, Elizabeth M.

    2010-01-01

    I am pleased to be part of this symposium to celebrate the life and work of Peter Bachrach. Although my focus is the relevance of Peter's ideas of power to law, I want to begin with some personal comments as well as raise some final thoughts, drawing on others' contributions. Like so many of Peter's other students, I adored him. Peter's joy in…

  14. Theories of Power, Poverty, and Law: In Commemoration of the Contributions of Peter Bachrach--Power, Law, and Final Thoughts: The Contributions of Peter Bachrach

    ERIC Educational Resources Information Center

    Schneider, Elizabeth M.

    2010-01-01

    I am pleased to be part of this symposium to celebrate the life and work of Peter Bachrach. Although my focus is the relevance of Peter's ideas of power to law, I want to begin with some personal comments as well as raise some final thoughts, drawing on others' contributions. Like so many of Peter's other students, I adored him. Peter's joy in…

  15. 77 FR 14773 - Vigue, Peter A.; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Vigue, Peter A.; Notice of Filing Take notice that on March 6, 2012, Peter A. Vigue submitted for filing, an application for authority to hold interlocking positions, pursuant to...

  16. R. S. Peters' Normative Conception of Education and Educational Aims

    ERIC Educational Resources Information Center

    Katz, Michael S.

    2009-01-01

    This article aims to highlight why R. S. Peters' conceptual analysis of "education" was such an important contribution to the normative field of philosophy of education. In the article, I do the following: 1) explicate Peters' conception of philosophy of education as a field of philosophy and explain his approach to the philosophical analysis of…

  17. Ritual, Imitation and Education in R. S. Peters

    ERIC Educational Resources Information Center

    Warnick, Bryan R.

    2009-01-01

    This article reconstructs R. S. Peters' underlying theory of ritual in education, highlighting his proposed link between ritual and the imitation of teachers. Rituals set the stage for the imitation of teachers and they invite students to experience practices whose value is not easily discernable from the outside. For Peters, rituals facilitate…

  18. Against the Corporate Culture Ideology: An Interview with Peter Mayo

    ERIC Educational Resources Information Center

    Suoranta, Juha

    2010-01-01

    This article presents an interview with Peter Mayo, author and expert in the field of sociology of adult education, on his major influences in this area, his books, and his views on the role of radical adult education and radical scholarship in the future. In the interview, Peter Mayo states that his initial view of adult education was quite a…

  19. Ritual, Imitation and Education in R. S. Peters

    ERIC Educational Resources Information Center

    Warnick, Bryan R.

    2009-01-01

    This article reconstructs R. S. Peters' underlying theory of ritual in education, highlighting his proposed link between ritual and the imitation of teachers. Rituals set the stage for the imitation of teachers and they invite students to experience practices whose value is not easily discernable from the outside. For Peters, rituals facilitate…

  20. Against the Corporate Culture Ideology: An Interview with Peter Mayo

    ERIC Educational Resources Information Center

    Suoranta, Juha

    2010-01-01

    This article presents an interview with Peter Mayo, author and expert in the field of sociology of adult education, on his major influences in this area, his books, and his views on the role of radical adult education and radical scholarship in the future. In the interview, Peter Mayo states that his initial view of adult education was quite a…

  1. 77 FR 26538 - Vigue, Peter A.; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-04

    ... Energy Regulatory Commission Vigue, Peter A.; Notice of Filing Take notice that on April 26, 2012, Peter A. Vigue submitted for filing, a supplement to the application for authority to hold interlocking..., but will not serve to make protestants parties to the proceeding. Any person wishing to become a party...

  2. Peter V. Karpovich: transforming the strength paradigm.

    PubMed

    Todd, Jan; Todd, Terry

    2003-05-01

    One of the most important figures in the public's acceptance of weight training as an acceptable activity for athletes was Russian-born physician Peter V. Karpovich of Springfield College, Springfield, MA. Karpovich, like most early 20th-century educators, opposed weight training for athletes and held a low opinion of weightlifting as an activity in general. However, he became strength science's most eminent and visible advocate after witnessing a demonstration of weightlifting organized by Bob Hoffman of the York Barbell Company in 1940. Following that demonstration, Karpovich conducted several seminal studies that examined the bedrock beliefs on which the arguments normally cited against lifting were built-that it would make a person slow and inflexible-in short, muscle-bound. His research consistently revealed that those beliefs were in error. Later, he went on to collaborate with Jim Murray on the first science-based book on the subject of strength training, Weight Training in Athletics, published in 1956.

  3. Rehabilitation: disability ethics versus Peter Singer.

    PubMed

    McPherson, Gary W; Sobsey, Dick

    2003-08-01

    This commentary discusses utilitarian bioethics currently articulated by Peter Singer, one of the most widely known bioethicists of the 21st century. His controversial concepts of personhood and replaceability have important implications for people with disabilities, caregivers, and rehabilitation in general. Singer suggests that people with severe disabilities should not be considered persons and therefore have no rights or status in ethical issues. In addition, he argues that, although some people with less severe disabilities qualify as persons, their potential quality of life is significantly compromised by disability and therefore it may be ethically desirable to eliminate them so that their resources can be used for someone with superior potential. We reject these ideas, and suggest that those involved in rehabilitation carefully consider these ideas because they imply that rehabilitation is an immoral act unless it results in full and typical function.

  4. NMR Spectroscopy: Processing Strategies (by Peter Bigler)

    NASA Astrophysics Data System (ADS)

    Mills, Nancy S.

    1998-06-01

    Peter Bigler. VCH: New York, 1997. 249 pp. ISBN 3-527-28812-0. $99.00. This book, part of a four-volume series planned to deal with all aspects of a standard NMR experiment, is almost the exact book I have been hoping to find. My department has acquired, as have hundreds of other undergraduate institutions, high-field NMR instrumentation and the capability of doing extremely sophisticated experiments. However, the training is often a one- or two-day experience in which the material retained by the faculty trained is garbled and filled with holes, not unlike the information our students seem to retain. This text, and the accompanying exercises based on data contained on a CD-ROM, goes a long way to fill in the gaps and clarify misunderstandings about NMR processing.

  5. An interview with Peter H. Buschang.

    PubMed

    Buschang, Peter H; dos Santos-Pinto, Ary; Araújo, Eustáquio; Ribeiro, Gerson Luiz Ulema; Jacob, Helder Baldi; Gandini Júnior, Luiz Gonzaga

    2014-01-01

    Dr. Peter Buschang is regent professor and director of orthodontic research. He has been at Texas A&M University Baylor College of Dentistry since 1988. Dr. Buschang received his PhD in 1980 from the University of Texas at Austin; he spent 3 years as a NIDR postdoctoral fellow at the University of Connecticut, and five years as a FRSQ scholar at the University of Montreal. Every year, Dr. Buschang teaches in 16 different courses, 7 of which he directs. In addition to more than 100 lecture hours per year, he spends hundreds of hours mentoring students. For his teaching efforts, Dr. Buschang was awarded the Robert E. Gaylord Award of Excellence in Orthodontic education in 1992, 1998, 2004, and 2010. He also gives 1-2 day evidence-based CE courses throughout the world. The residents he has taught recently honored him by pledging to fund the Peter H. Buschang Endowed Professorship of Orthodontics. His research interests pertain to craniofacial growth and assessment of treatment effects. Dr. Buschang has been funded regularly over the years by the Medical Research Council of Canada, Fonds de le Recherche en Santé du Québec, the NIH, and the American Association of Orthodontics Foundation. He has mentored over 140 Master's and PhD students, and 49 dental students. Dr. Buschang has published over 250 peer-reviewed articles, 15 book chapters and 198 abstracts. He has given over 150 invited talks and lectures in 14 different countries. For his work with the American Board of Orthodontics, Dr. Buschang was awarded the Earl E. and Wilma S. Shepard Award. Dr. Buschang is the only non-orthodontist ever to have been made an honorary member of both the American Association of Orthodontics (2005) and the Edward H. Angle Society of Orthodontics (2009), the two most prestigious orthodontic groups.

  6. [The Graefe memorial stone--in memory of A. von Graefe's contributions in Heiden].

    PubMed

    Koelbing, H M; Speiser, P

    1990-01-01

    Between 1859 and 1869, Albrecht von Graefe used to spend some weeks in September in Heiden, a small health resort in Eastern Switzerland. During his "holidays", however, the hotel "Freihof", where he lived, was transformed into a most active unit of ophthalmic surgery. A memorial stone, rediscovered and restored thanks to the endeavour of Professor Peter Speiser of St. Gallen, remembers this episode, which was of some importance not only for local tourism, but also for the young Swiss ophthalmology of the time.

  7. von Willebrand Disease.

    PubMed

    Swami, Arjun; Kaur, Varinder

    2016-01-01

    von Willebrand disease (vWD) is the most common inherited disorder of hemostasis and comprises a spectrum of heterogeneous subtypes. Significant advances have been made in understanding von Willebrand factor ( vWF) gene mutations, resultant physiologic deficits in the vWF peptide, and their correlation to clinical presentation. Diagnostic tests for this disorder are complex, and interpretation requires a thorough understanding of the underlying pathophysiology by the practicing physician. The objective of this review is to summarize our current understanding of pathophysiology, laboratory investigations, and evolving treatment paradigm of vWD with the availability of recombinant von Willebrand factor.

  8. Mutation Analysis of B3GALTL in Peters Plus Syndrome

    PubMed Central

    Reis, Linda M.; Tyler, Rebecca C.; Abdul-Rahman, Omar; Trapane, Pamela; Wallerstein, Robert; Broome, Diane; Hoffman, Jodi; Khan, Aneal; Paradiso, Christina; Ron, Nitin; Bergner, Amanda; Semina, Elena V.

    2009-01-01

    Peters Plus syndrome comprises ocular anterior segment dysgenesis (most commonly Peters anomaly), short stature, hand anomalies, distinctive facial features, and often other additional defects and is inherited in an autosomal-recessive pattern. Mutations in the β1,3-glucosyltransferase gene (B3GALTL) were recently reported in 20 out of 20 patients with Peters Plus syndrome. In our study, B3GALTL was examined in four patients with typical Peters Plus syndrome and four patients that demonstrated a phenotypic overlap with this condition. Mutations in B3GALTL were identified in all four patients with typical Peters Plus syndrome, while no mutations were found in the remaining four patients that demonstrated some but not all characteristic features of the syndrome. The previously reported common mutation, c.660+1G>A, accounted for 75% of the mutant alleles in our Peters Plus syndrome population. In addition, two new mutant alleles, c.459+1G>A and c.230insT, were identified and predicted to result in truncated protein products. These data confirm an important role for B3GALTL in causing typical Peters Plus syndrome, and suggest that this gene may not be implicated in syndromic cases that involve Peters’ anomaly but lack other classic features of this complex condition. PMID:18798333

  9. Von Willebrand disease

    MedlinePlus

    ... done to diagnose this disease include: Bleeding time Blood typing Factor VIII level Platelet function analysis Platelet count Ristocetin cofactor test Von Willebrand factor specific tests ... invasive procedure. Blood plasma or certain factor VIII preparations may also ...

  10. Wernher von Braun

    NASA Image and Video Library

    1959-03-03

    Dr. von Braun, Director of the Development Operations Divisons, and Dr. Debus, Director of the Missile Firing Laboratory; Army Ballistic Missile Agency (ABMA), in the blockhouse during the launch of the Pioneer IV, March 3, 1959.

  11. Wernher von Braun

    NASA Image and Video Library

    1960-11-03

    Marshall Space Flight Center’s (MSFC) Director, Dr. Wernher von Braun, is pictured here with Army Ballistic Missile Agency’s (ABMA) Commanding General, J.B. Medaris, before a display of Army missles at the ABMA test lab.

  12. Wernher von Braun

    NASA Image and Video Library

    1970-06-27

    Marshall Space Flight Center (MSFC) Director Dr. Eberhard Rees conversing with former Center Director, Dr. Wernher von Braun, who along with his wife and son, participated in MFSC's Tenth Anniversary Celebration Picnic held at the Center's picnic area.

  13. Wernher von Braun

    NASA Image and Video Library

    1959-01-01

    Marshall Space Flight Center Director Wernher von Braun presents General J.B. Medaris with a new golf bag. General Medaris, (left) was a Commander of the Army Ballistic Missile Agency (ABMA) in Redstone Arsenal, Alabama during 1955 to 1958.

  14. Wernher von Braun

    NASA Image and Video Library

    1962-09-11

    Marshall Space Flight Center Director Dr. Wernher von Braun explains a detail from a Saturn IB mockup and engine to President John F. Kennedy, Vice President Lyndon Johnson and other guests, September 11, 1962.

  15. Wernher von Braun

    NASA Image and Video Library

    1960-09-08

    President Dwight D. Eisenhower and MSFC Director Dr. Wernher von Braun share a joke as other dignitaries look on. Eisenhower was visiting Marshall to participate in the September 8, 1960 dedication ceremony.

  16. Wernher von Braun

    NASA Image and Video Library

    1962-09-11

    President John F. Kennedy, Vice President Lyndon B. Johnson and Marshall Space Flight Center Director Dr. Wernher von Braun at the Redstone Arsenal Airfield, September 11, 1962. Kennedy and Johnson visited the Marshall Center to tour national space facilities.

  17. von Willebrand Factor Test

    MedlinePlus

    ... Was this page helpful? Also known as: VWF:Ag; VWF:RCo; von Willebrand Panel; Ristocetin Cofactor Formal ... may include: Ratio of VWF:RCo to VWF:Ag Factor VIII binding assay Platelet VWF studies Collagen ...

  18. Wernher von Braun

    NASA Image and Video Library

    1967-08-28

    Marshall Space Flight Center’s (MSFC) director, Dr. Wernher von Braun (right), inspects a component of a laser experiment being conducted in MSFC’s Space Sciences Laboratory during a tour on August 28, 1967.

  19. Wernher von Braun

    NASA Image and Video Library

    1969-06-04

    In this photograph, Guenter Ogger of Capitol Magazine, West Germany, greets Marshall Space Flight Center Director, Dr. Wernher von Braun. Mr. Ogger interviewed the famous rocket scientist for his magazine.

  20. Wernher von Braun

    NASA Image and Video Library

    1962-01-01

    Dr. Wernher von Braun, Director of the Marshall Space Flight Center (MSFC), during his tour of the Space information Division of North American Aviation (NAA) in Downey, California, where the Saturn SII stage was developed.

  1. Wernher von Braun

    NASA Image and Video Library

    1967-10-17

    Dr. von Braun, Director of the Marshall Space Flight Center, listens attentively to a briefing on the metal forming techniques by Dr. Mathias Siebel of the Manufacturing and Engineering Laboratory at MSFC on October 17, 1967.

  2. Wernher von Braun

    NASA Image and Video Library

    1965-11-05

    In this photograph, Marshall Space Flight Center Director, Dr. Wernher von Braun, presents a Co-Inventor’s award to MSFC employee Martin Hall of the Mechanical Engineering Laboratory during the NASA Anniversary ceremony.

  3. Wernher von Braun

    NASA Image and Video Library

    1961-10-01

    Dr. Wernher von Braun, Director of Marshall Space Flight Center (MSFC), teams up with Senator Robert S. Kerr, a chairman of the Senate Committee on Aeronautical and Space Sciences to break ground for MSFC's new Central Laboratory and Office Facility.

  4. Wernher von Braun

    NASA Image and Video Library

    1964-10-14

    This photograph, dated October 14, 1964, was taken at the Marned Spacecraft Center, now the Johnson Space Center in Houston, Texas. Dr. von Braun is shown looking over consoles in the Manned Spaceflight Control Center.

  5. Wernher von Braun

    NASA Image and Video Library

    1964-10-14

    This is a photograph that was made on October 14, 1964 of Dr. von Braun while he toured the Marned Spacecraft Center, now the Johnson Space Center in Houston, Texas. He is shown inspecting a Gemini-Agena Docking Simulator.

  6. Wernher von Braun

    NASA Image and Video Library

    1961-01-01

    Dr. von Braun is shown in this photograph, which was probably taken in the early 1960s, with members of his management team. Pictured from left to right are, Werner Kuers, Director of the Manufacturing Engineering Division; Dr. Walter Haeussermarn, Director of the Astrionics Division; Dr. William Mrazek, Propulsion and Vehicle Engineering Division; Dr. von Braun; Dieter Grau, Director of the Quality Assurance Division; Dr. Oswald Lange, Director of the Saturn Systems Office; and Erich Neubert , Associate Deputy Director for Research and Development.

  7. Wernher von Braun

    NASA Image and Video Library

    1970-02-24

    Dr. von Braun was honored with a series of farewell events and ceremonies prior to his reassignment to NASA Headquarters in Washington, D.C. Alabama Governor Brewer greets Dr. von Braun following his speech at the front of the Madison County Courthouse in Huntsville, Alabama on February 24, 1970. Behind are Madison County Commissioner James Record, Huntsville Mayor Joe Davis, and U.S. Senator Sparkman.

  8. Dr. Wernher Von Braun

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. Wernher Von Braun (right), Deputy Associate Administrator for planning, National Aeronautics and Space Administration, inspects the mockup of the Saturn Workshop during a visit marking the 10th anniversary of the Marshall Center. Shown with Dr. Von Braun, from left to right, are Karl Heimburg, Director of the astronautics lab; Herman K. Weidner, Director of Science and Engineering, and George Hardy of the Astronautics lab.

  9. Dr. Wernher Von Braun

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. Wernher Von Braun (right), Deputy Associate Administrator for Planning, National Aeronautics and Space Administration, inspects the mockup of the Saturn Workshop during a visit marking the 10th anniversary of the Marshall Center. Shown with Dr. Von Braun, from left to right, are Karl Heimburg, Director of the Astronautics Lab; Herman K. Weidner, Director of Science and Engineering, and George Hardy of the Astronautics Lab.

  10. Wernher von Braun

    NASA Image and Video Library

    1964-03-24

    Marshall Space Flight Center Director Dr. Wernher von Braun presents Lady Bird Johnson with an inscribed hard hat during the First Lady's March 24, 1964 visit. While at the Marshall Center, Mrs. Johnson addressed Center employees, toured facilities and witnessed test firings of a Saturn I first stage and an F-1 engine. Dr. von Braun is wearing a Texas hat presented to him months earlier by Lyndon Johnson during a visit to the Johnson ranch in Texas.

  11. Wernher von Braun

    NASA Image and Video Library

    1930-01-01

    Dr. von Braun was among a famous group of rocket experimenters in Germany in the 1930s. This photograph is believed to be made on the occasion of Herman Oberth's Kegelduese liquid rocket engine being certified as to performance during firing. From left to right are R. Nebel, Dr. Ritter, Mr. Baermueller, Kurt Heinish, Herman Oberth, Klaus Riedel, Wernher von Braun, and an unidentified person.

  12. Pilot Peter Hoag and HL-10

    NASA Technical Reports Server (NTRS)

    1969-01-01

    Air Force Major Peter Hoag stands in front of the HL-10 Lifting Body. Maj. Hoag joined the HL-10 program in 1969 and made his first glide flight on June 6, 1969. He made a total of 8 flights in the HL-10. They included the fastest lifting-body flight, which reached Mach 1.861 on Feb. 18, 1970. The HL-10 was one of five heavyweight lifting-body designs flown at NASA's Flight Research Center (FRC--later Dryden Flight Research Center), Edwards, California, from July 1966 to November 1975 to study and validate the concept of safely maneuvering and landing a low lift-over-drag vehicle designed for reentry from space. Northrop Corporation built the HL-10 and M2-F2, the first two of the fleet of 'heavy' lifting bodies flown by the NASA Flight Research Center. The contract for construction of the HL-10 and the M2-F2 was $1.8 million. 'HL' stands for horizontal landing, and '10' refers to the tenth design studied by engineers at NASA's Langley Research Center, Hampton, Va. After delivery to NASA in January 1966, the HL-10 made its first flight on Dec. 22, 1966, with research pilot Bruce Peterson in the cockpit. Although an XLR-11 rocket engine was installed in the vehicle, the first 11 drop flights from the B-52 launch aircraft were powerless glide flights to assess handling qualities, stability, and control. In the end, the HL-10 was judged to be the best handling of the three original heavy-weight lifting bodies (M2-F2/F3, HL-10, X-24A). The HL-10 was flown 37 times during the lifting body research program and logged the highest altitude and fastest speed in the Lifting Body program. On Feb. 18, 1970, Air Force test pilot Peter Hoag piloted the HL-10 to Mach 1.86 (1,228 mph). Nine days later, NASA pilot Bill Dana flew the vehicle to 90,030 feet, which became the highest altitude reached in the program. Some new and different lessons were learned through the successful flight testing of the HL-10. These lessons, when combined with information from it's sister ship, the M2

  13. Solution of Peter Winkler's Pizza Problem

    NASA Astrophysics Data System (ADS)

    Cibulka, Josef; Kynčl, Jan; Mészáros, Viola; Stolař, Rudolf; Valtr, Pavel

    Bob cuts a pizza into slices of not necessarily equal size and shares it with Alice by alternately taking turns. One slice is taken in each turn. The first turn is Alice's. She may choose any of the slices. In all other turns only those slices can be chosen that have a neighbor slice already eaten. We prove a conjecture of Peter Winkler by showing that Alice has a strategy for obtaining 4/9 of the pizza. This is best possible, that is, there is a cutting and a strategy for Bob to get 5/9 of the pizza. We also give a characterization of Alice's best possible gain depending on the number of slices. For a given cutting of the pizza, we describe a linear time algorithm that computes Alice's strategy gaining at least 4/9 of the pizza and another algorithm that computes the optimal strategy for both players in any possible position of the game in quadratic time. We distinguish two types of turns, shifts and jumps. We prove that Alice can gain 4/9, 7/16 and 1/3 of the pizza if she is allowed to make at most two jumps, at most one jump and no jump, respectively, and the three constants are the best possible.

  14. Life and Scientific Work of Peter Guthrie Tait

    NASA Astrophysics Data System (ADS)

    Gilston Knott, Cargill

    2015-04-01

    Preface; 1. Memoir - Peter Guthrie Tait; 2. Experimental work; 3. Mathematical work; 4. Quaternions; 5. Thomson and Tait, 'Tand T', or Thomson and Tait's natural philosophy; 6. Other books; 7. Addresses, reviews, and correspondence; 8. Popular scientific articles; Bibliography; Index.

  15. The Learning Organization Made Plain. An Interview with Peter Senge.

    ERIC Educational Resources Information Center

    Training and Development, 1991

    1991-01-01

    Peter Senge explains how his book, "The Fifth Disciple," will change minds about systems thinking, personal growth, and work. He talks about what led him to write the book and what it takes to become a learning organization. (JOW)

  16. The Peter Pan and Wendy syndrome: a marital dynamic.

    PubMed

    Quadrio, C

    1982-06-01

    A marital system is described which features an unfaithful and narcissistic husband, Peter Pan, and a long suffering and depressed wife, Wendy. The dynamics of their individual adjustments are examined as well as the symbiotic nature of the dyadic relationship. Other characters take their parts--Tinker Bell, Tiger Lily, and Little Lost Boys. Peter's infidelities belie a firm attachment to his Wendy/mother whilst she depends upon him for protection from forbidden impulses.

  17. Laparoscopic cholecystectomy and the Peter Pan syndrome.

    PubMed

    Orlando, G; Bellini, P; Borioni, R; Pace, A

    2000-08-01

    We report the case of a patient who experienced hemobilia a few weeks after undergoing laparoscopic cholecystectomy (LC). This condition was due to the rupture of a pseudo-aneurysm of the right hepatic artery in the common bile duct, probably caused by a clip erroneously fired during LC on the lateral right wall of the vessel. It also caused the formation of multiple liver abscesses and the onset of sepsis. This life-threatening complication led to melena, fever, epigastric pain, pancreatitis, liver dysfunction, and severe anemia, requiring urgent hospitalization and operation. In the operating theater, the fistula was closed, the liver abscesses drained, and a Kehr tube inserted. Thereafter, the patient's general condition improved, and she is now well. LC is often considered to be the gold standard for the management of symptomatic cholelithiasis. However, recent data have undermined that opinion. The apparent advantages offered by LC in the short term (less pain, speedier recovery, shorter hospital stay, and lower costs) have been overwhelmed by the complications that occur during long-term follow-up. When the late downward trend in the bile duct and the vascular injury rate are taken into consideration, the learning curve is prolonged. Therefore, LC should be regarded as the surgical equivalent of a modern Peter Pan-i.e., it is like a young adult who should make definitive steps toward becoming an adult but does not succeed in doing so. We report the case of a patient who experienced hemobilia a few weeks after undergoing laparoscopic cholecystectomy. Based on the facts in this case, we argue that the endoscopic procedure still needs to be perfected and cannot yet be considered the gold standard for selected cases of gallstone disease.

  18. Peter Holland: a pioneer of occupational medicine.

    PubMed Central

    Murray, R

    1992-01-01

    The earliest recorded occupational health service in this country was that established in a cotton spinning factory at Quarry Bank Mill in Cheshire. The mill was built in 1784 by Samuel Greg and his partners. They employed local labour and also some parish apprentices. Happily, Samuel Greg was a good christian and, having created a modern factory and a model village with a church and a school, he was equally concerned for the physical welfare of his employees. Accordingly, he appointed a doctor to make pre-employment examinations of the apprentices and to visit regularly to deal with the health problems of a community of some 400 people. The man he chose was Peter Holland of Sandlebridge, who had served his medical apprenticeship under Dr Charles White of Manchester. The first record of the employment of a doctor was in 1796, but from 1804 to 1845 (doubtless in response to the early factory legislation) each visit of the doctor was entered in a day book with either an indication of fitness to work or details of the treatment required. The complete record consists of two hardback foolscap notebooks that provide a fascinating insight into the medical practice of the times when the industrial revolution was just getting under way. One of the more interesting features is the preservation of medical secrecy. Dr Holland made his comments on the case in shorthand and his instructions in longhand. By a fortunate coincidence the key to the shorthand was discovered and this has now been largely transcribed. Although much of the content of the diaries is the day by day practice of medicine at the time, there are many illuminating glimpses of the early practice of occupational medicine. Images PMID:1606023

  19. Wernher von Braun

    NASA Image and Video Library

    1958-01-31

    Jet Propulsion Laboratory Director Dr. James Pickering, Dr. James van Allen of the State University of Iowa, and Army Ballistic missionile Agency Technical Director Dr. Wernher von Braun triumphantly display a model of the Explorer I, America's first satellite, shortly after the satellite's launch on January 31, 1958. The Jet Propulsion Laboratory packed and tested the payload, a radiation detection experiment designed by Dr. van Allen. Dr. von Braun's rocket team at Redstone Arsenal in Huntsville, Alabama, developed the Juno I launch vehicle, a modified Jupiter-C.

  20. Wernher von Braun

    NASA Image and Video Library

    1969-02-28

    Marshall Space Flight Center’s (MSFC) Dr. Ernst Stuhlinger, Director of Research Projects Office; and Dr. Wernher von Braun, center director, along with others, took a swim in the Neutral Buoyancy Simulator (NBS) at MSFC. A safety diver adjusts scuba equipment worn by von Braun, while Stuhlinger adjusts his weight belt prior to entering the tank. In the NBS, subjects were weighted to a neutrally buoyant condition underwater to perform and practice tasks in a simulated weightless condition as would be encountered in space.

  1. von Willebrand factor and von Willebrand disease.

    PubMed

    Matsui, Taei; Hamako, Jiharu

    von Willebrand factor (VWF) has two major roles in hemostasis, as a form of molecular glue which functions in platelet plug formation and as a protective transporter for coagulation factor VIII (FVIII). VWF shows a multimeric chain structure composed of 270 kDa subunits containing binding domains for FVIII, platelet and collagens. Biosynthesis, storage, secretion of VWF and the cleavage process by ADAMTS13 (a disintegrin-like and metalloproteinase with thrombospondin type 1 repeats 13) regulating VWF activity have been elucidated. von Willebrand disease (VWD) is an autosomal bleeding disorder, first documented in 1926, caused by quantitative or qualitative deficiency of VWF. The classification and molecular pathogenesis of VWD have been developed during a 90-year period based on clinical laboratory analysis of VWF, and structure-function analysis of mutant VWF with amino acid substitutions (genetic changes). VWF is a unique and very large multifunctional plasma protein, the hemostatic activity of which is dynamically regulated by physiological shear stress in the blood stream.

  2. Wernher von Braun

    NASA Image and Video Library

    1950-01-01

    Dr. von Braun stands beside a model of the upper stage (Earth-returnable stage) of the three-stage launch vehicle built for the series of the motion picture productions of space flight produced by Walt Disney in the mid-1950's.

  3. Wernher von Braun

    NASA Image and Video Library

    1960-01-01

    This is a photograph of Dr. von Braun in front of a Saturn rocket hardware transporter. He appears to be addressing a group. Behind him are workers and other NASA officials. There is no date on the photograph. It may have been taken in the late 1960s.

  4. Wernher von Braun

    NASA Image and Video Library

    1959-03-04

    Dr. Wernher von Braun, Director of the U.S. Army Ballistic Missile Agency's (ABMA) Development Operations Division, talks to Huntsville Mayor R. B. "Speck" Searcy, center, and Army Ordnance Missile Command (ARMC) Major General John B. Medaris, right, during "Moon Day" celebrations in downtown Huntsville, Alabama. (Courtesy of Huntsville/Madison County Public Library)

  5. Wernher von Braun

    NASA Image and Video Library

    1959-01-01

    In this picture, Dr. Wernher von Braun, who was serving as Director of the Army Ballistic Missile Agency's (ABMA) Development Operations Division, is shown posed with his Mercedes 220SE automobile in front of Redstone Building 4488, which houses the ABMA.

  6. Dr. Wernher Von Braun

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Shown viewing the Apollo telescope mockup are, from left to right, Charles Donlan, deputy associate administrator for manned space flight; Dr. Wernher Von Braun, Marshall Space Flight Center director; William Horton, astrionics lab; Dr. Thomas Paine, NASA deputy administrator; Warner Kuers, director of the ME lab.

  7. Wernher von Braun

    NASA Image and Video Library

    1961-01-01

    During his tenure as Director of the Marshall Space Flight Center (MSFC), Dr. von Braun enjoyed personally touring the Center's many space-related laboratories and facilities. This photo taken about 1961 shows him examining a test set up in the Center's Manufacturing Engineering Laboratory.

  8. Wernher von Braun

    NASA Image and Video Library

    1962-04-16

    Dr. von Braun (right) and Astronaut John Glenn examine a model of a lunar landing stage during a talk on the manned lunar exploration program by about sixty key officials of the nation's space program at the Marshall Space Flight Center (MSFC).

  9. Wernher von Braun

    NASA Image and Video Library

    1961-01-01

    Dr. von Braun tried out a floating platform in the Marshall Space Flight Center Manufacturing Engineering Laboratory. This was a test rig to help determine how future astronauts will be able to perform maintenance tasks in the weightlessness in space. This photograph is believed to have been taken in 1961.

  10. Wernher von Braun

    NASA Image and Video Library

    1954-07-01

    Dr. Wernher von Braun (center), then Chief of the Guided Missile Development Division at Redstone Arsenal, Alabama, discusses a "bottle suit" model with Dr. Heinz Haber (left), an expert on aviation medicine, and Willey Ley, a science writer on rocketry and space exploration. The three men were at the Disney studios appearing in the motion picture, entitled "Man in Space."

  11. Wernher von Braun

    NASA Image and Video Library

    1971-01-31

    Dr. Wernher von Braun, NASA Deputy Associate Administrator for Future Programs, uses binoculars to monitor data on the closed-circuit TV screen in the Firing Room of the Launch Control Center at Kennedy Space Center (KSC) during the final preparation for the Apollo 14 launch.

  12. Wernher von Braun

    NASA Image and Video Library

    1969-02-28

    Dr. E. Stuhlinger, Dr. W. von Braun, and Dr. J. Piccard, along with others, take a swim in the Neutral Buoyancy Simulator (NBS) at the Marshall Space Flight Center. The NBS was instrumental in providing a zero-gravity environment where astronauts could practice tasks assigned for up coming space flights.

  13. Dr. Wernher Von Braun

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Shown viewing the Apollo telescope mockup are, from left to right, Charles Donlan, deputy associate administrator for manned space flight; Dr. Wernher Von Braun, Marshall Space Flight Center director; William Horton, astrionics lab; Dr. Thomas Paine, NASA deputy administrator; Warner Kuers, director of the ME lab.

  14. Dr. Wernher Von Braun

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Marshall Space Flight Center director Wernher Von Braun and his family were honored with a series of events prior to his relocation to Washington, D.C. where he was assigned duties at NASA headquarters as deputy associate administrator for planning. Here he is shown with General Richard Drury and Hazel Toftoy, widow of General H.N. Toftoy.

  15. Wernher von Braun

    NASA Image and Video Library

    1961-03-01

    Dr. von Braun, Director of the Marshall Space Flight Center, spoke of the progress in the Saturn Program during his appearance before the Senate Committee on Aeronautical and Space Sciences. He was accompanied by Dr. Robert C. Seamans, Jr., Associate Administrator of the National Aeronautics and Space Administration (NASA).

  16. Wernher von Braun

    NASA Image and Video Library

    1965-04-13

    Walt Disney toured the West Test Area during his visit to the Marshall Space Flight Center on April 13, 1965. The three in center foreground are Karl Heimburg, Director, Test Division; Dr. von Braun, Director, MSFC; and Walt Disney. The Dynamic Test Stand with the S-1C stage being installed is in the background.

  17. Energetische Verwertung von Biomasse

    NASA Astrophysics Data System (ADS)

    Zahoransky, Richard; Allelein, Hans-Josef; Bollin, Elmar; Oehler, Helmut; Schelling, Udo

    Etwa 0,1% der Solarenergie wandeln sich durch Photosynthese aus dem Kohlendioxid der Luft in Biomasse um. Die Biomassen sind als Festbrennstoff nutzbar oder zu gasförmigen Brennstoffen weiterverarbeitbar. Zwei Arten von Biomassen sind zu unterscheiden: Anfallende Biomasse

  18. Dr. Wernher Von Braun

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Marshall Space Flight Center director Wernher Von Braun and his family were honored with a series of events prior to his relocation to Washington, D.C. where he was assigned duties at NASA headquarters as deputy associate administrator for planning. Here he is shown with General Richard Drury and Hazel Toftoy, widow of General H.N. Toftoy.

  19. Opera and madness: Britten's Peter Grimes--a case study.

    PubMed

    Durà-Vilà, G; Bentley, D

    2009-12-01

    In this paper, Britten's opera Peter Grimes (1945) is used as an illustrative case study through which to examine the depiction of psychiatric disorders in opera. It is argued that Peter Grimes is a powerful example of how opera, in the hands of a great composer, can become an invaluable tool for examining subjective human experience. After a brief discussion of opera as a vehicle to express emotions, various operas are drawn upon to provide a historical perspective and to demonstrate the long interconnection existing between opera and madness. An in-depth analysis of Peter Grimes, its background and central character, is then provided, in order to demonstrate how opera can elicit empathy for individuals affected by mental health problems.

  20. Wernher von Braun

    NASA Image and Video Library

    1960-01-01

    Edward O. Buckbee, the first Director of the Alabama Space Science Center (left), and Dr. Wernher von Braun (right) view a demonstration of a simulated spacecraft which uses an actual hybrid rocket engine for liftoff, hover, and landing. The display was presented to the Alabama Space Science Center, later renamed the U.S. Space and Rocket Center, by United Technology Center, a division of United Aircraft.

  1. Wernher von Braun

    NASA Image and Video Library

    1967-10-01

    Dr. von Braun encouraged his laboratory directors and other managers at the Marshall Space Flight Center (MSFC) to adopt a "hands-on" approach to managing the technical challenges they confronted in developing the Saturn rockets for the Marned Lunar Landing Program. He is shown here asking a question about welding in an MSFC manufacturing and engineering laboratory. This photograph was made on or about October 17, 1967.

  2. Wernher von Braun

    NASA Image and Video Library

    1963-03-28

    Dr. von Braun, Director of the Marshall Space Flight Center (MSFC), and Dr. Debus, Director of the Launch Operations Center, at Complex 34 prior to the Launch of the SA-4 (the fourth flight of Saturn I), March 28, 1963. The mission conducted the second "Project Highwater" experiment, which the upper stage ejected 30,000 gallons of ballast water in the upper atmosphere for a physics experiment.

  3. Wernher von Braun

    NASA Image and Video Library

    1966-06-21

    Dr. Joseph Randall, a laser expert at Marshall Space Flight Center (MSFC), explains one of the projects he is working on to a group composed of Federal Republic of Germany and MSFC officials. From left are: Dr. Randall; Minister for Scientific Research of Federal Republic of Germany, Dr. Gerhard Stolenberg; Director of MSFC Astrionics Lab, Dr. Walter Haeusserman; Head of Space Research Federal Republic of Germany, Max Mayer; MSFC Director Dr. von Braun; MSFC Deputy Director Dr. Elberhard Rees.

  4. Wernher von Braun

    NASA Image and Video Library

    1968-10-01

    Dr. von Braun inside the KC-135 in flight. The KC-135 provide NASA's Reduced-Gravity Program the unique weightlessness or zero-g environment of space flight for testing and training of human and hardware reactions. The recent version, KC-135A, is a specially modified turbojet transport which flies parabolic arcs to produce weightlessness periods of 20 to 25 seconds and its cargo bay test area is approximately 60 feet long, 10 feet wide, and 7 feet high.

  5. Wernher von Braun

    NASA Image and Video Library

    1960-01-01

    In this photo, Director of the US Army Ballistic Missile Agency (ABMA) Development Operations Division, Dr. Wernher von Braun, is standing before a display of Army missiles celebrating ABMA's Fourth Open House. The missiles in the background include (left to right) a satellite on a Juno II shroud with a Nike Ajax pointing left in front of a Jupiter missile. The Lacrosse is in front of the Juno II. The Nike Hercules points skyward in front of the Juno II and the Redstone.

  6. The Quantum Logical Challenge: Peter Mittelstaedt's Contributions to Logic and Philosophy of Science

    NASA Astrophysics Data System (ADS)

    Beltrametti, E.; Dalla Chiara, M. L.; Giuntini, R.

    2017-04-01

    Peter Mittelstaedt's contributions to quantum logic and to the foundational problems of quantum theory have significantly realized the most authentic spirit of the International Quantum Structures Association: an original research about hard technical problems, which are often "entangled" with the emergence of important changes in our general world-conceptions. During a time where both the logical and the physical community often showed a skeptical attitude towards Birkhoff and von Neumann's quantum logic, Mittelstaedt brought into light the deeply innovating features of a quantum logical thinking that allows us to overcome some strong and unrealistic assumptions of classical logical arguments. Later on his intense research on the unsharp approach to quantum theory and to the measurement problem stimulated the increasing interest for unsharp forms of quantum logic, creating a fruitful interaction between the work of quantum logicians and of many-valued logicians. Mittelstaedt's general views about quantum logic and quantum theory seem to be inspired by a conjecture that is today more and more confirmed: there is something universal in the quantum theoretic formalism that goes beyond the limits of microphysics, giving rise to interesting applications to a number of different fields.

  7. Advocating Science for All: An Interview with Peter J. Fensham

    ERIC Educational Resources Information Center

    Cardellini, Liberato

    2013-01-01

    After providing some glimpses of his private life, Peter Fensham, a leading figure of the prestigious Faculty of Education, Monash University (and now emeritus professor at Queensland University, Brisbane, Australia), gives some suggestions about the conditions that help students to learn meaningfully. He began his career in the field of physical…

  8. Portrait Face-Off: Gilbert Stuart vs. Peter Max

    ERIC Educational Resources Information Center

    Crumpecker, Cheryl

    2012-01-01

    When art classes are short and infrequent, it is always a challenge to meet required state and national standards. A unit comparing and contrasting Peter Max's Pop art portraits with the realistic style of Gilbert Stuart's presidential portraits provides an opportunity to address a huge number of these requirements. Focus can change with the age…

  9. Team Leader: Tom Peters--TAP Information Services

    ERIC Educational Resources Information Center

    Library Journal, 2005

    2005-01-01

    Tom Peters packs 36 hours of work into the confines of a 24-hour day. Without breaking a sweat, he juggles multiple collaborative projects, which currently include an Illinois academic library shared storage facility; a multistate virtual reference and instruction service for blind and visually impaired individuals (InfoEyes); a virtual meeting…

  10. My Journey with Peter: Moving Ideas that Matter

    ERIC Educational Resources Information Center

    Blyth, Dale A.

    2012-01-01

    Youth development lost a pioneer and a champion, Peter Benson, in October. Benson was a pioneer whose ideas mattered and a champion of approaches to research and its use in the community that has made a difference around the world. Benson's work, life, and spirit have helped transform people's understanding of young people, what it takes to…

  11. Shaping the Global Civil Society: An Interview with Michael Peters

    ERIC Educational Resources Information Center

    Heraud, Richard; Tesar, Marek

    2017-01-01

    Professor Michael A. Peters has worked in an era of transformation that has taken him from a labour-intensive paper-based form of production to the computerised reproduction of thought, and the current shift in the publishing landscape from a reader-subscription to an author-pays model. Most of what he has learned in publishing and editing he has…

  12. University of Florida potato variety trials spotlight: 'Peter Wilcox'

    USDA-ARS?s Scientific Manuscript database

    'Peter Wilcox’ is a fresh market potato variety selected from progeny of a cross between B0810-1 and B0918-5, and tested under the pedigree B1816-5 by K.G. Haynes. It was jointly released by United States Department of Agriculture, North Carolina Agricultural Research Service, Agricultural Experimen...

  13. R. S. Peters' "The Justification of Education" Revisited

    ERIC Educational Resources Information Center

    Cuypers, Stefaan E.

    2012-01-01

    In his 1973 paper "The Justification of Education" R. S. Peters aspired to give a non-instrumental justification of education. Ever since, his so-called "transcendental argument" has been under attack and most critics conclude that it does not work. They have, however, thrown the baby away with the bathwater, when they furthermore concluded that…

  14. Peter Effect in the Preparation of Reading Teachers

    ERIC Educational Resources Information Center

    Binks-Cantrell, Emily; Washburn, Erin K.; Joshi, R. Malatesha; Hougen, Martha

    2012-01-01

    The Peter Effect (Applegate & Applegate, 2004) claimed that one cannot be expected to give what one does not possess. We applied this notion to reading teacher preparation and hypothesized that teacher educators who do not possess an understanding of basic language constructs would not prepare teacher candidates with an understanding of these…

  15. R. S. Peters and the Concept of Education

    ERIC Educational Resources Information Center

    Beckett, Kelvin Stewart

    2011-01-01

    In this essay Kelvin Beckett argues that Richard Peters's major work on education, "Ethics and Education," belongs on a short list of important texts we can all share. He argues this not because of the place it has in the history of philosophy of education, as important as that is, but because of the contribution it can still make to the future of…

  16. Peters' Concept of "Education as Initiation": Communitarian or Individualist?

    ERIC Educational Resources Information Center

    Cotter, Richard

    2013-01-01

    A central element of Richard Peters' philosophy of education has been his analysis of "education as initiation". Understanding initiation is internally related to concepts of community and what it may mean to be a member. The concept of initiation assumes a mutually interdependent, dynamic relationship between the individual and community that…

  17. Radical Visions: Five Picture Books by Peter Sis.

    ERIC Educational Resources Information Center

    Latham, Don

    2000-01-01

    Examines five picture books by author/illustrator Peter Sis, and how they deal explicitly with people who through extraordinary journeys develop extraordinary ways of seeing the world. Discusses use of paratextual elements, multiple formats, multiple layers of narrative, and a merging of texts and pictures. Suggests ways these books might be used…

  18. Shaping the Global Civil Society: An Interview with Michael Peters

    ERIC Educational Resources Information Center

    Heraud, Richard; Tesar, Marek

    2017-01-01

    Professor Michael A. Peters has worked in an era of transformation that has taken him from a labour-intensive paper-based form of production to the computerised reproduction of thought, and the current shift in the publishing landscape from a reader-subscription to an author-pays model. Most of what he has learned in publishing and editing he has…

  19. Portrait Face-Off: Gilbert Stuart vs. Peter Max

    ERIC Educational Resources Information Center

    Crumpecker, Cheryl

    2012-01-01

    When art classes are short and infrequent, it is always a challenge to meet required state and national standards. A unit comparing and contrasting Peter Max's Pop art portraits with the realistic style of Gilbert Stuart's presidential portraits provides an opportunity to address a huge number of these requirements. Focus can change with the age…

  20. Snatched from the Sea: The Survival of "Peter Wilkins."

    ERIC Educational Resources Information Center

    Merchant, Peter

    1990-01-01

    Discusses Robert Patlock's 1750 novel "The Life and Adventures of Peter Wilkins." Argues that the novel is more than just a late contribution to the tradition of the imaginary voyage, but a novel in which the voyage being traced is both the hero's and the reader's. (MG)

  1. Advocating Science for All: An Interview with Peter J. Fensham

    ERIC Educational Resources Information Center

    Cardellini, Liberato

    2013-01-01

    After providing some glimpses of his private life, Peter Fensham, a leading figure of the prestigious Faculty of Education, Monash University (and now emeritus professor at Queensland University, Brisbane, Australia), gives some suggestions about the conditions that help students to learn meaningfully. He began his career in the field of physical…

  2. Peter Jarvis and the Understanding of Adult Learning

    ERIC Educational Resources Information Center

    Illeris, Knud

    2017-01-01

    By comparing Peter Jarvis' understanding of learning with two other approaches--which Jarvis himself has referred to as "the most comprehensive": Etienne Wenger's "social theory of learning" and my own psychologically oriented theory of "the three dimensions of learning"--it becomes evident that Jarvis' understanding…

  3. Marginal Experiments: Peter Brook and Stepping out Theatre Company

    ERIC Educational Resources Information Center

    Harpin, Anna

    2010-01-01

    This article juxtaposes the recent work of Peter Brook with a Bristol-based mental health service-user collective--Stepping Out Theatre Company. Informed by field-work with the company, this chapter explores the aesthetic and political relationship between professional, experimental theatre work and community-based performance practice. Drawing…

  4. Peters' Concept of "Education as Initiation": Communitarian or Individualist?

    ERIC Educational Resources Information Center

    Cotter, Richard

    2013-01-01

    A central element of Richard Peters' philosophy of education has been his analysis of "education as initiation". Understanding initiation is internally related to concepts of community and what it may mean to be a member. The concept of initiation assumes a mutually interdependent, dynamic relationship between the individual and community that…

  5. My Journey with Peter: Moving Ideas that Matter

    ERIC Educational Resources Information Center

    Blyth, Dale A.

    2012-01-01

    Youth development lost a pioneer and a champion, Peter Benson, in October. Benson was a pioneer whose ideas mattered and a champion of approaches to research and its use in the community that has made a difference around the world. Benson's work, life, and spirit have helped transform people's understanding of young people, what it takes to…

  6. London in Space and Time: Peter Ackroyd and Will Self

    ERIC Educational Resources Information Center

    Green, Andrew

    2013-01-01

    This paper explores the treatment of London by two authors who are profoundly influenced by the concept of the power of place and the nature of urban space. The works of Peter Ackroyd, whose writings embody, according to Onega (1997, p. 208) "[a] yearning for mythical closure" where London is "a mystic centre of…

  7. Peter Wilcox: A new purple-skin, yellow flesh fresh market potato cultivar

    USDA-ARS?s Scientific Manuscript database

    Peter Wilcox is a new, medium-maturing, purple-skin, yellow-flesh potato cultivar for fresh market. Peter Wilcox also produces light-colored chips, although it is being released primarily as a fresh market potato because of its skin and flesh colors. Tubers of Peter Wilcox are attractive, smooth, wi...

  8. Theories of Power, Poverty, and Law: In Commemoration of the Contributions of Peter Bachrach--The Challenge of Peter Bachrach

    ERIC Educational Resources Information Center

    Lukes, Steven

    2010-01-01

    Peter Bachrach had a remarkable impact on those who encountered him in person and on generations of readers. Judith Baer vividly captures, among other things, his inspiring, emboldening influence on his students and the sheer fun it was to be with him. My recollections are of exciting, forward moving, intense, and probing arguments, in private and…

  9. Dr. Wernher Von Braun

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. Thomas Paine, Deputy Administrator of the National Aeronautics and Space Administration, examines an ordinary man's shoe outfitted for use in the Saturn I workshop. Pictured from the left in the Saturn I workshop mockup are William Brooksbank, propulsion and vehicle engineering laboratory; Dr. Paine; Dr. Wernher Von Braun, Marshall Center director; Colonel Clare F. Farley, Executive Officer in the Office Of The Administrator; and Charles J. Donlan, Deputy Associate Administrator for Manned Space Flight, Technical. the shoe Dr. Paine is holding has a unique fastener built into the sole to allow an astronaut to move about on the workshop floor and to remain in one position if he desires.

  10. Von Karman swirling flows

    NASA Astrophysics Data System (ADS)

    Zandbergen, P. J.; Dijkstra, D.

    A development history is presented for research on the problem of swirling flow infinite disks from its formulation by von Karman in 1921 through the treatments of Batchelor (1951) and Stewartson (1953) to the present, with a view to both its one-disk and two-disk forms. Attention is given to the stability of the stationary solutions for these problems, and to the case where the radii of the disks are finite. The question as to the extent to which the Karman swirling flow occurs in a finite radial geometry is noted to be of fundamental importance.

  11. Wernher von Braun

    NASA Image and Video Library

    1959-03-01

    In this photo, Director of the U.S. Army Ballistic Missile Agency's (ABMA) Development Operations Division, Dr. Wernher von Braun, and Director of Missile Firing Division, Dr. Kurt Debus, are shown with unidentified individuals, discussing two components that would make up the Pioneer IV Lunar Probe. The mercury batteries (left) were used to power the radio transmitter, cosmic radiation counter and other instruments in Pioneer IV. The conical shroud placed over the instruments of Pioneer IV was plated with gold to improve conductivity. The metal surface also served as the anterna for the probe's instruments signaling back to the Earth receiving stations.

  12. von Willebrand Disease (For Parents)

    MedlinePlus

    ... problems because the levels or functioning of these blood components needed for clotting are abnormal. continue Types of von Willebrand Disease As with many conditions, there are various forms ... of von Willebrand factor in the blood is reduced; the level of factor VIII also ...

  13. The Travails of Criticality: Understanding Peter McLaren's Revolutionary Vocation. An Article Review of Peter McLaren, "Pedagogy of Insurrection" (New York: Peter Lang, 2015)

    ERIC Educational Resources Information Center

    Baldacchino, John

    2017-01-01

    This is an article review of Peter McLaren's "Pedagogy of Insurrection" (New York: Peter Lang, 2015). While it seeks to position McLaren's work within the context of critical pedagogy, this paper also assesses McLaren from the wider discussion of Marxist--Hegelian discourse as it evolved within the Left. Engaging with McLaren critically,…

  14. Vera Peters and the curability of Hodgkin disease

    PubMed Central

    Cowan, D.H.

    2008-01-01

    The middle of the 20th century hailed the realization that patients with Hodgkin disease could be cured. Through the groundbreaking work of Vera Peters, patients with a localized form of the disorder, previously thought to be incurable, were shown to be cured by extended-field radiotherapy. This important observation, although not immediately accepted, opened the minds of physicians to take more positive investigative and therapeutic approaches. Peters also introduced and championed the concept of tumour staging in Hodgkin disease and the use of prognostic factors in clinical decision-making. This novel approach led to high cure rates with radiotherapy in localized disease and provided a scientific basis for the subsequent use of chemotherapy in disseminated disease, resulting in a very high cure rate in patients with all stages of Hodgkin disease. PMID:19008994

  15. Peters anomaly in cri-du-chat syndrome.

    PubMed

    Hope, William C; Cordovez, Jose A; Capasso, Jenina E; Hammersmith, Kristin M; Eagle, Ralph C; Lall-Trail, Joel; Levin, Alex V

    2015-06-01

    The cri-du-chat syndrome is a rare genetic disorder caused by deletions in the short arm of chromosome 5. It presents with a distinctive catlike high-pitched cry, psychomotor delays, microcephaly, craniofacial abnormalities, and, in many cases, ocular findings. We report the first child with cri-du-chat and the findings of unilateral corneal staphyloma due to Peters anomaly and retinal dysplasia. Copyright © 2015 American Association for Pediatric Ophthalmology and Strabismus. Published by Elsevier Inc. All rights reserved.

  16. Performance Evaluation Tests for Environmental Research (PETER): Collected Papers.

    DTIC Science & Technology

    1981-07-01

    with the source batteries and to aid selec- tion of new tests for possible inclusion in PETER. One table was constructed for each source METIID battery... for Navy are available but most use the following three condi- enlisted personnel in physical health , mental health tions: (a) black and white words (BW...or above the norms for Navy enlisted each subsequent day (e.g. Day 1 to 2, 1 to 3, .. personnel in physical health , mental health and I to 15

  17. Peter Satir -- investigating the structural basis for cell function.

    PubMed

    Sale, W S; Barkalow, K L

    2001-04-01

    Peter Satir has devoted his research career to elucidating the structural basis for ciliary motility. His ingenious use of structural analysis, combined with identification of powerful model systems, provided a model for the sliding microtubule hypothesis of ciliary bending and led to the discovery that dynein is a 'minus-end'-directed motor whose regulated activity underpins the bending motion of cilia. Here, we focus on ciliary motility to illustrate Satir's pioneering contributions to cell biology.

  18. Abnormal centromere-chromatid apposition (ACCA) and Peters' anomaly.

    PubMed

    Wertelecki, W; Dev, V G; Superneau, D W

    1985-08-01

    Abnormal centromere-chromatid apposition (ACCA) was noted in a patient with Peters' anomaly. Previous reports of ACCA emphasized its association with tetraphocomelia and other congenital malformations (Roberts, SC Phocomelia, Pseudothalidomide Syndromes). This report expands the array of congenital malformations associated with ACCA and emphasizes the diagnostic importance of ocular defects for the ascertainment of additional cases of ACCA and its possible relationship with abnormal cell division.

  19. Wernher von Braun

    NASA Image and Video Library

    1960-09-08

    On September 8, 1960 President Dwight D. Eisenhower visited Huntsville, Alabama to dedicate a new NASA field center in honor of General George C. Marshall, Eisenhower's wartime colleague and the founder of the famous Marshall Plan for European recover after World War II. The new George C. Marshall Space Flight Center was placed under the control of Dr. Wernher Von Braun shown here talking with President Eisenhower. As parto f his remarks dedicating the center, President Eisenhowe refereed to General Marshall as a "man of yar, yet a builder of peace". the Marshall Center's first major assignment including building the huge Saturn V rocket that launched human beings on their first journey to the surface of the moon in 1969.

  20. von Karman Vortices

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Each of these swirling clouds is the result of a meteorological phenomenon known as a von Karman vortex. These vortices appeared over Alexander Selkirk Island in the southern Pacific Ocean. Rising precipitously from the surrounding waters, the island's highest point is nearly a mile (1.6 km) above sea level. As wind-driven clouds encounter this obstacle, they flow around it to form large, spinning eddies. This image was acquired by Landsat 7's Enhanced Thematic Mapper plus (ETM+) sensor on September 15, 1999. This is a false-color composite image made using shortwave infrared, infrared, and near-infrared wavelengths. Image provided by the USGS EROS Data Center Satellite Systems Branch.

  1. Wernher von Braun

    NASA Image and Video Library

    1971-07-26

    During the Apollo 15 launch activities in the launch control center's firing room 1 at Kennedy Space Center, Dr. Wernher von Braun, NASA's Deputy Associate Administrator for planning, takes a closer look at the launch pad through binoculars. The fifth manned lunar landing mission, Apollo 15 (SA-510), carrying a crew of three astronauts: Mission commander David R. Scott, Lunar Module pilot James B. Irwin, and Command Module pilot Alfred M. Worden Jr., lifted off on July 26, 1971. Astronauts Scott and Irwin were the first to use a wheeled surface vehicle, the Lunar Roving Vehicle, or the Rover, which was designed and developed by the Marshall Space Flight Center, and built by the Boeing Company. Astronauts spent 13 days, nearly 67 hours, on the Moon's surface to inspect a wide variety of its geological features.

  2. Dr. Wernher Von Braun

    NASA Technical Reports Server (NTRS)

    1960-01-01

    On September 8, 1960 President Dwight D. Eisenhower visited Huntsville, Alabama to dedicate a new NASA field center in honor of General George C. Marshall, Eisenhower's wartime colleague and the founder of the famous Marshall Plan for European recover after World War II. The new George C. Marshall Space Flight Center was placed under the control of Dr. Wernher Von Braun shown here talking with President Eisenhower. As parto f his remarks dedicating the center, President Eisenhowe refereed to General Marshall as a 'man of yar, yet a builder of peace'. the Marshall Center's first major assignment including building the huge Saturn V rocket that launched human beings on their first journey to the surface of the moon in 1969.

  3. Von Hippel's disease in association with von Recklinghausen's neurofibromatosis.

    PubMed Central

    Thomas, J V; Schwartz, P L; Gragoudas, E S

    1978-01-01

    Ten members of a large family who showed manifestations of either von Hippel-Lindau disease or von Recklinghausen's neurofibromatosis were examined. Three of 10 members were found to have retinal angiomas which had not been present on fundus examination 3 years previously. These angiomas were associated with ocular and systemic signs of neurofibromatosis. These cases show overlapping manifestations of different phakomatoses and provide support for the concept of a common aetiology for these diseases. Images PMID:101230

  4. von Braun and German Publisher

    NASA Technical Reports Server (NTRS)

    1969-01-01

    In this photograph, Guenter Ogger of Capitol Magazine, West Germany, greets Marshall Space Flight Center Director, Dr. Wernher von Braun. Mr. Ogger interviewed the famous rocket scientist for his magazine.

  5. Von Karman and JATO Team

    NASA Technical Reports Server (NTRS)

    1940-01-01

    Dr. Theodore von Karman (black coat) sketches out a plan on the wing of an airplane as his JATO engineering team looks on. From left to right: Dr. Clark B. Millikan, Dr.Martin Summerfield, Dr. Theodore von Karman, Dr. Frank J. Malina and pilot, Capt. Homer Boushey. Captain Boushey would become the first American to pilot an airplane that used JATO (Jet Assisted Take-Off) solid propellent rockets.

  6. Formulating an Anarchist Sociology: Peter Kropotkin's Reading of Herbert Spencer.

    PubMed

    Adams, Matthew S

    2016-01-01

    The work of Herbert Spencer was a crucial influence on the development of Peter Kropotkin's historical sociology. However, scholars have underestimated this relationship; either overlooking it entirely, or minimizing Kropotkin's attachment to Spencer with the aim of maintaining the utility of his political thought in the present. This article contests these interpretations by analyzing Kropotkin's reading of Spencer's epistemological, biological, and political ideas. It argues that Kropotkin was engaged in a critical dialogue with Spencer, incorporating many Spencerian principles in his own system, but also using this reading to articulate a distinctive anarchist politics.

  7. A tribute to Peter A. Rona: A Russian Perspective

    NASA Astrophysics Data System (ADS)

    Sagalevich, Anatoly; Lutz, Richard A.

    2015-11-01

    In July 1985 Peter Rona led a cruise of the National Oceanic and Atmospheric Administration (NOAA) ship Researcher as part of the NOAA Vents Program and discovered, for the first time, black smokers, massive sulfide deposits and vent biota in the Atlantic Ocean. The site of the venting phenomena was the Trans-Atlantic Geotraverse (TAG) Hydrothermal Field on the east wall of the rift valley of the Mid-Atlantic Ridge at 26°08‧N; 44°50‧W (Rona, 1985; Rona et al., 1986). In 1986, Peter and an international research team carried out multidisciplnary investigations of both active and inactive hydrothermal zones of the TAG field using the R/V Atlantis and DSV Alvin, discovering two new species of shrimp (Rimicaris exoculata and Chorocaris chacei) (Williams and Rona, 1986) and a hexagonal-shaped form (Paleodictyon nodosum) thought to be extinct (Rona et al., 2009). In 1991 a Russian crew aboard the R/V Akademik Mstislav Keldysh, with two deep-diving, human-occupied submersibles (Mir-1 and Mir-2) (Fig. 1), had the honor of having Peter Rona and a Canadian IMAX film crew from the Stephen Low Company on board to visit the TAG hydrothermal vent field. This was the first of many deep-sea interactions between Russian deep-sea scientists and their colleagues from both the U.S. and Canada. This expedition to the TAG site was part of a major Russian undersea program aimed at exploring extreme deep-sea environments; between 1988 and 2005, the Mir submersibles visited hydrothermal vents and cold seep areas in 20 deep-sea regions throughout the world's oceans (Sagalevich, 2002). Images of several of these areas (the TAG, Snake Pit, Lost City and 9°50‧N vent fields) were obtained using an IMAX camera system emplaced for the first time within the spheres of the Mir submersibles and DSV Alvin in conjunction with the filming of science documentaries (e.g., ;Volcanoes of the Deep Sea;) produced by the Stephen Low Company in conjunction with Emory Kristof of National Geographic and

  8. Peter the Great: Linking Military Strategy to National Objectives in Imperial Russia

    DTIC Science & Technology

    1999-04-01

    ruler of Russia’s Romanov dynasty . Peter was an extraordinary leader who reformed Russia domestically and combined his diplomatic and military skills to...Young Peter Peter Alexeiovich Romanov was born on May 30, 1672 to Tsar Alexei Mikhailovich Romanov and his second wife, Natalia Naryshkina. Although...routes from India to Mecklenburg and beyond. 46 Appendix A Timeline 1558-81 Ivan the Terrible’s Baltic campaign. 1613-1645 Reign of Tsar Mikhail Romanov

  9. Wernher von Braun

    NASA Image and Video Library

    1969-07-01

    This photograph depicts Dr. von Braun (fourth from far right) and other NASA officials surveying the deep-sea research submarine "Ben Franklin." Named for American patriot and inventor Ben Franklin, who discovered the Gulf Steam, the 50-foot Ben Franklin was built between 1966 and 1968 in Switzerland for deep-ocean explorer Jacques Piccard and the Grumman Aircraft Engineering Corporation. The submersible made a famous 30-day drift dive off the East Coast of the United States and Canada in 1969 mapping the Gulf Stream's currents and sea life, and also made space exploration history by studying the behavior of aquanauts in a sealed, self-contained, self-sufficient capsule for NASA. On July 14, 1969, the Ben Franklin was towed to the high-velocity center of the Stream off the coast of Palm Beach, Florida. With a NASA observer on board, the sub descended to 1,000 feet off of Riviera Beach, Florida and drifted 1,400 miles north with the current for more than four weeks, reemerging near Maine. During the course of the dive, NASA conducted exhaustive analyses of virtually every aspect of onboard life. They measured sleep quality and patterns, sense of humor and behavioral shifts, physical reflexes, and the effects of a long-term routine on the crew. The submarine's record-shattering dive influenced the design of Apollo and Skylab missions and continued to guide NASA scientists as they devised future marned space-flight missions.

  10. Wernher von Braun

    NASA Image and Video Library

    1969-07-01

    This photograph depicts Dr. von Braun (at right, showing his back) and other NASA officials surveying the deep-sea research submarine "Ben Franklin." Named for American patriot and inventor Ben Franklin, who discovered the Gulf Steam, the 50-foot Ben Franklin was built between 1966 and 1968 in Switzerland for deep-ocean explorer Jacques Piccard and the Grumman Aircraft Engineering Corporation. The submersible made a famous 30-day drift dive off the East Coast of the United States and Canada in 1969 mapping the Gulf Stream's currents and sea life, and also made space exploration history by studying the behavior of aquanauts in a sealed, self-contained, self-sufficient capsule for NASA. On July 14, 1969, the Ben Franklin was towed to the high-velocity center of the Stream off the coast of Palm Beach, Florida. With a NASA observer on board, the sub descended to 1,000 feet off of Riviera Beach, Florida and drifted 1,400 miles north with the current for more than four weeks, reemerging near Maine. During the course of the dive, NASA conducted exhaustive analyses of virtually every aspect of onboard life. They measured sleep quality and patterns, sense of humor and behavioral shifts, physical reflexes, and the effects of a long-term routine on the crew. The submarine's record-shattering dive influenced the design of Apollo and Skylab missions and continued to guide NASA scientists as they devised future marned space-flight missions.

  11. Richard von Volkmann

    PubMed Central

    Willy, Christian; Schneider, Peter; Engelhardt, Michael; Hargens, Alan R.

    2008-01-01

    Richard von Volkmann (1830–1889), one of the most important surgeons of the 19th century, is regarded as one of the fathers of orthopaedic surgery. He was a contemporary of Langenbeck, Esmarch, Lister, Billroth, Kocher, and Trendelenburg. He was head of the Department of Surgery at the University of Halle, Germany (1867–1889). His popularity attracted doctors and patients from all over the world. He was the lead physician for the German military during two wars. From this experience, he compared the mortality of civilian and war injuries and investigated the general poor hygienic conditions in civilian hospitals. This led him to introduce the “antiseptic technique” to Germany that was developed by Lister. His powers of observation and creativity led him to findings and achievements that to this day bear his name: Volkmann’s contracture and the Hueter-Volkmann law. Additionally, he was a gifted writer; he published not only scientific literature but also books of children’s fairy tales and poems under the pen name of Richard Leander, assuring him a permanent place in the world of literature as well as orthopaedics. PMID:18196438

  12. Von Willebrand factor processing.

    PubMed

    Brehm, Maria A

    2017-01-31

    Von Willebrand factor (VWF) is a multimeric glycoprotein essential for primary haemostasis that is produced only in endothelial cells and megakaryocytes. Key to VWF's function in recruitment of platelets to the site of vascular injury is its multimeric structure. The individual steps of VWF multimer biosynthesis rely on distinct posttranslational modifications at specific pH conditions, which are realized by spatial separation of the involved processes to different cell organelles. Production of multimers starts with translocation and modification of the VWF prepropolypeptide in the endoplasmic reticulum to produce dimers primed for glycosylation. In the Golgi apparatus they are further processed to multimers that carry more than 300 complex glycan structures functionalized by sialylation, sulfation and blood group determinants. Of special importance is the sequential formation of disulfide bonds with different functions in structural support of VWF multimers, which are packaged, stored and further processed after secretion. Here, all these processes are being reviewed in detail including background information on the occurring biochemical reactions.

  13. John P. Peters and the committee of 430 physicians.

    PubMed Central

    Lundberg, George D.

    2002-01-01

    John Peters and his committee had a few basic goals. One was that local, state, and federal governments needed to provide money to construct facilities, support medical research and education, and care for the poor. And they wanted experts to call the shots. Over time, Peters and the committee got what they wanted for the most part: Hill-Burton money for building the hospitals, the rise of the National Institutes of Health, Medicare, Medicaid, a Veterans Administration system, and new and expanded medical schools. The experts calling the shots included David Kessler at the Food and Drug Administration and Surgeon General C. Everett Koop. In the halcyon days of American health system reform, back in 1993, Yale's Paul Beeson wrote about the Committee of 430 Physicians and its goals in the Pharos of Alpha Omega Alpha. Beeson was optimistic and he quoted from my 1991 JAMA health system reform editorial as a sharp contrast to what Fishbein had written - although coincidentally, we both quote Lincoln. My editorial began, "'with malice toward none, with charity for all...' so spoke Abraham Lincoln in his second inaugural address recognizing that he had no political consensus regarding either the constitutionality of states seceding or the morality of slavery being abolished. Nonetheless, he knew what was right and was able, through persuasive, often inspiring rhetoric, to conclude a bloody and decisive Civil War and constitute the foundation for this great republic.... Yet access to basic medical care for all of our inhabitants is still not a reality in this country. There are many reasons for this, not the least of which is a long-standing, systematic, institutionalized racial discrimination.... An aura of inevitablitiy is upon us. It is not acceptable morally, ethically, or economically for so many of our people to be medically uninsured or seriously underinsured. We can solve this problem. We have the knowledge and the resources, the skills, the time, and the moral

  14. John P. Peters and the committee of 430 physicians.

    PubMed

    Lundberg, George D

    2002-01-01

    John Peters and his committee had a few basic goals. One was that local, state, and federal governments needed to provide money to construct facilities, support medical research and education, and care for the poor. And they wanted experts to call the shots. Over time, Peters and the committee got what they wanted for the most part: Hill-Burton money for building the hospitals, the rise of the National Institutes of Health, Medicare, Medicaid, a Veterans Administration system, and new and expanded medical schools. The experts calling the shots included David Kessler at the Food and Drug Administration and Surgeon General C. Everett Koop. In the halcyon days of American health system reform, back in 1993, Yale's Paul Beeson wrote about the Committee of 430 Physicians and its goals in the Pharos of Alpha Omega Alpha. Beeson was optimistic and he quoted from my 1991 JAMA health system reform editorial as a sharp contrast to what Fishbein had written - although coincidentally, we both quote Lincoln. My editorial began, "'with malice toward none, with charity for all...' so spoke Abraham Lincoln in his second inaugural address recognizing that he had no political consensus regarding either the constitutionality of states seceding or the morality of slavery being abolished. Nonetheless, he knew what was right and was able, through persuasive, often inspiring rhetoric, to conclude a bloody and decisive Civil War and constitute the foundation for this great republic.... Yet access to basic medical care for all of our inhabitants is still not a reality in this country. There are many reasons for this, not the least of which is a long-standing, systematic, institutionalized racial discrimination.... An aura of inevitablitiy is upon us. It is not acceptable morally, ethically, or economically for so many of our people to be medically uninsured or seriously underinsured. We can solve this problem. We have the knowledge and the resources, the skills, the time, and the moral

  15. [Pheochromocytoma and von Recklinghausen's disease].

    PubMed

    Rabii, R; Fekak, H; Moufid, K; Joual, A; Bennani, S; el Mrini, M; Benjelloun, S

    2002-07-01

    The association between von Recklinghausen's disease and pheochromocytoma is present about 10% of cases. We report a case of 49 years old women who presented with elevated blood pressure and von Recklinghausen's neurofibromatosis. Laboratory examination showed a marked level in the urinary excretion of cathecholamine. The computed tomography showed a right adrenal tumor suggesting a pheochromocytoma. The adrenalectomy was realised by transabdominal approach and the histological examination confirmed a benign pheochromocytoma. The authors discuss the pathogenetic hypothesis of this rare pathological association, the diagnostic methods and the therapeutic procedure.

  16. Otto Peters on Distance Education: The Industrialization of Teaching and Learning. Routledge Studies in Distance Education.

    ERIC Educational Resources Information Center

    Keegan, Desmond, Ed.

    This book contains new and previously published translations of 11 essays and articles about the industrialization of teaching and learning in distance education that were originally published in German by Otto Peters between 1965 and 1993. A "Preface" (Desmond Keegan) and an introduction placing Peters' writings in their historical…

  17. Vision and Elusiveness in Philosophy of Education: R. S. Peters on the Legacy of Michael Oakeshott

    ERIC Educational Resources Information Center

    Williams, Kevin

    2009-01-01

    Despite his elusiveness on important issues, there is much in Michael Oakeshott's educational vision that Richard Peters quite rightly wishes to endorse. The main aim of this essay is, however, to consider Peters' justifiable critique of three features of Oakeshott's work. These are (1) the rigidity of his distinction between vocational and…

  18. Reflections on Peters' View of the Nature and Purpose of Work in Philosophy of Education

    ERIC Educational Resources Information Center

    Aspin, D. N.

    2013-01-01

    In this article I describe the analytic approach adopted by Peters, his colleagues and followers of the "London line" in the 1960s and 1970s and argue that, even in those times, other approaches to philosophy of education were being valued and practised. I show that Peters and his colleagues later became aware of the need for philosophy of…

  19. The Future of the Digital Library: An Interview with Tom Peters

    ERIC Educational Resources Information Center

    Morrison, James L.; Peters, Tom

    2005-01-01

    This article presents an interview with Tom Peters, an academic librarian and founder of TAP Information Services, a firm that provides consulting services to libraries and other organizations in the information industry. Peters also serves as a consultant to LibraryCity, an ambitious project that seeks to make thousands of e-books in easy-to-use…

  20. The "Physically Educated" Person: Physical Education in the Philosophy of Reid, Peters and Aristotle

    ERIC Educational Resources Information Center

    MacAllister, James

    2013-01-01

    This article will derive a definition and account of the physically educated person, through an examination of the philosophy of Andrew Reid, Richard Peters and Aristotle. Initially, Reid's interpretation of Peters' views about the educational significance of practical knowledge (and physical education) will be considered. While it will…

  1. The "Physically Educated" Person: Physical Education in the Philosophy of Reid, Peters and Aristotle

    ERIC Educational Resources Information Center

    MacAllister, James

    2013-01-01

    This article will derive a definition and account of the physically educated person, through an examination of the philosophy of Andrew Reid, Richard Peters and Aristotle. Initially, Reid's interpretation of Peters' views about the educational significance of practical knowledge (and physical education) will be considered. While it will…

  2. Otto Peters on Distance Education: The Industrialization of Teaching and Learning. Routledge Studies in Distance Education.

    ERIC Educational Resources Information Center

    Keegan, Desmond, Ed.

    This book contains new and previously published translations of 11 essays and articles about the industrialization of teaching and learning in distance education that were originally published in German by Otto Peters between 1965 and 1993. A "Preface" (Desmond Keegan) and an introduction placing Peters' writings in their historical…

  3. Reflections on Peters' View of the Nature and Purpose of Work in Philosophy of Education

    ERIC Educational Resources Information Center

    Aspin, D. N.

    2013-01-01

    In this article I describe the analytic approach adopted by Peters, his colleagues and followers of the "London line" in the 1960s and 1970s and argue that, even in those times, other approaches to philosophy of education were being valued and practised. I show that Peters and his colleagues later became aware of the need for philosophy of…

  4. Ripples from a Passing Ship: Memories; and a Legacy of Richard Peters

    ERIC Educational Resources Information Center

    Harris, Kevin

    2013-01-01

    This paper outlines aspects and dimensions of my "relationship" with Richard Peters from 1966 onward. The underlying suggestion is that, while Peters' contribution to philosophy of education was undeniably of major proportions, both that contribution and his legacy are institutional rather than substantive. (Contains 15 notes.)

  5. Unique Presentation of Corneal Opacity in Peters Plus Syndrome: An Unusual Form of Peters Anomaly Showing Tissue Repair in Serial Analysis.

    PubMed

    de Nie, Karlijn F; Wesseling, Pieter; Eggink, Catharina A

    2016-02-01

    To report an unusual case of bilateral Peters anomaly in Peters Plus syndrome. Systematic analysis and description of relevant clinical features, histopathological, and genetic findings. A premature neonate, born after 34 weeks of gestation, presented with typical features of Peters Plus syndrome and bilateral corneal opacification with central clearing. Peters Plus syndrome was confirmed by the identification of a homozygous mutation in the B3GALTL gene. When a flat anterior chamber was observed and perforation was suspected both corneas necessitated corneal transplantation (left cornea transplanted at 4 weeks of age, right cornea at the age of 9 weeks). Histopathological analysis of the left cornea revealed a central defect with absence of all corneal layers except for the corneal epithelium. The right cornea revealed central absence of the corneal endothelium and Descemet membrane as well, but the central stroma consisted of a cellular meshwork rich in fibroblasts. There were no signs of iridocorneal or keratolenticular adhesions. We report the histopathology of serially obtained left and right cornea of a premature neonate with Peters Plus syndrome. As demonstrated in the left cornea, the child had a central defect of all corneal layers except for the corneal epithelium. Histopathological analysis of the right cornea obtained 5 weeks later revealed that the defect had induced fibrovascular tissue repair. The sequence of events we report in the corneas of our patient may help to better understand the pathogenesis of corneal (and anterior chamber) abnormalities in Peters Plus syndrome.

  6. [Peter of Abano, the 'Conciliator' between magic and science].

    PubMed

    Federici Vescovini, Graziella

    2008-01-01

    Peter of Abano is a personage belonging to history as well as to legend. In this analysis his historical physiognomy of scientist and physician is reconstructed on the basis of a better knowledge of his works in medicine and astronomy (now edited), a discipline, the latest one, in which he excelled in Medieval scientific context (The Lucidator dubitabilium astronomiae (astrologiae) can be read in the critical edition by G. Federici Vescovini, Padova, Esedra, 1992). He opposed extreme position in all fields, by styling himself 'Conciliator' of opposed tendencies. He often reconfirmed a rational concept of medicine and astronomy, which dispelled any demoniac and magic features, against the fanciful legend elaborated during the following centuries.

  7. STS-81 Mission Specialist Peter Wisoff suits up

    NASA Technical Reports Server (NTRS)

    1997-01-01

    STS-81 Mission Specialist Peter J. K. 'Jeff' Wisoff prepares for the fifth Shuttle- Mir docking as he waits in the Operations and Checkout (O&C) Building for the operation to fit him into his launch/entry suit to be completed. He conducted a spacewalk on his on his first Shuttle mission, STS- 57 and holds a doctorate degree in applied physics with an emphasis on lasers and semiconductor materials. He and five crew members will shortly depart the O&C and head for Launch Pad 39B, where the Space Shuttle Atlantis will lift off during a 7-minute window that opens at 4:27 a.m. EST, January 12.

  8. Retention of acoustic conditioning in St Peter's fish Sarotherodon galilaeus.

    PubMed

    Zion, B; Barki, A; Grinshpon, J; Rosenfeld, L; Karplus, I

    2011-03-01

    Groups of St Peter's fish Sarotherodon galilaeus were trained during 28 days of classical conditioning to respond to an acoustic signal by approaching a feeder. Their ability to retain the acoustically conditioned behaviour was tested after eight different intervals ranging from 12 to 188 days from termination of training. Retention tests comprised 7 consecutive days of retraining and the fish response was compared with that of naive fish. Fish response drastically diminished with time. After 55 days, there was no apparent expression of memory on the first test day but fish response was restored on subsequent retraining days, indicating the existence of latent memory. Six months from the end of training, there was no indication of behavioural retention and the response completely vanished. The study was conducted in the context of sea ranching, with classical conditioning used to gain control over fish location. In light of the present results, it is suggested that periodic reinforcement of the acoustically conditioned behaviour should be used.

  9. Peter B. Dews and pharmacological studies on behavior.

    PubMed

    Barrett, James E; Bergman, Jack

    2008-09-01

    The publications by Peter B. Dews of a series of five articles entitled "Studies on Behavior", beginning in 1955 and ending in 1959, were contributions of extraordinary significance in laying a foundation for the emergence of the discipline of behavioral pharmacology. The series of articles were rigorous in their approach, dramatic in terms of the results, and provocative in their implications. Published at the near half-century mark of the founding of the American Society for Pharmacological and Experimental Therapeutics, it is appropriate to now provide a Centennial Perspective on the impact of these studies over 50 years following their publication and to comment on the way in which they helped to influence the directions in which this discipline has evolved.

  10. Peters anomaly in a red kangaroo (Macropus rufus).

    PubMed

    Suedmeyer, Wm Kirk; Pearce, Jacqueline; Persky, Meredith; Houck, Marlys L

    2014-09-01

    A 10-mo-old female red kangaroo (Macropus rufus) presented with a unilateral congenital corneal opacity OD. Complete ophthalmic examination revealed a shallow anterior chamber and a focal area of corneal edema with multiple persistent pupillary membranes extending from the iris colarette to the corneal endothelium adjacent to the edematous area of cornea. High-resolution B-scan ultrasound of the anterior segment showed an area consistent with thinning of Descemet's membrane in the area of corneal edema. Ophthalmic examination and ultrasound findings are consistent with a diagnosis of Peters anomaly, a form of anterior segment dysgenesis. An electroretinogram performed on the affected animal did not reveal any specific abnormalities. Karyotype analyses revealed a normal diploid number (2n = 20, -XX), with an abnormal pericentric inversion in the second largest chromosomal pair. The kangaroo exhibits mild compensated vision deficits in the affected eye. The maternal and paternal adult pairing has been discontinued in an effort to prevent future offspring anomalies.

  11. Von Hippel-Lindau Disease

    MedlinePlus

    Von Hippel-Lindau disease (VHL) is a rare, genetic disease that causes tumors and cysts to grow in your body. The tumors can be either ... and, in men, their genital tract. Symptoms of VHL vary and depend on the size and location ...

  12. [Was Klaus von Mantrei the teacher of Hans von Gersdorff?].

    PubMed

    Vollmuth, R

    1996-01-01

    One of the most popular representatives of surgery at the end of the middle ages and the beginning modern era is the Strassburgian surgeon Hans von Gersdorff. Still we do not know very much about his life and his surgical teachers. Only one meister Nicklaus, called Mulartzt, is mentioned as such by the remarks in Gersdorffs 'Feldbuch der Wundarznei', but till today this surgeon could not be identified in more detail. This article now holds the thesis, that meister Nicklaus is probably identical with Klaus von Matrei (Metry), a well-known surgeon of the late 15th century. That cannot be fully proved yet, but a number of coinciding characteristics between the two and some further indications, that are explained, seem so significant, that the thesis can hardly be doubted.

  13. 1988 Horton Medal presented to Peter S. Eagleson

    NASA Astrophysics Data System (ADS)

    Rodriguez-Iturbe, Ignacio; Eagleson, Peter S.

    It is indeed a great honor for me, and also a great pleasure, to present to you the 1988 recipient of the Robert E. Horton Medal, Peter S. Eagleson. Shortly after it became public that Pete was the winner of this year's medal, I commented to my wife that, although I had never given a citation for an AGU medalist, this was one I would really love to give. The reason is simple: there is no one in the world who better represents the standards of excellence that a hydrologist hopes to achieve and that hydrologists hope our discipline will attain than Peter Eagleson.Pete did not start his research career in hydrology. In fact, his Ph.D. thesis in 1956 and his research up to 1965 were mainly in the field of sediment sorting and transport by waves on beaches. During this period he also investigated problems related to flow-induced vibrations of plates. His research in these areas was extremely successful, producing three chapters in books and about 20 journal papers in addition to many technical reports and journal discussions. Indeed, Pete had made his mark in wave theory and sediment transport, but it was good fortune for our field that starting about 1964 his interest in hydrology overcame all his past experience and assured a reputation in the waves and sediment field, and thus he embarked on a new adventure—bringing into hydrology the scientific rigor that existed in more academically established disciplines. With his strong fluid mechanics background—he still teaches that subject to undergraduates at MIT—Pete was ideally suited to lead the field toward new problems and also toward new approaches to old problems . . . and this he did indeed! Just in 1967 he and his students published six papers, most of them in Water Resources Research, which had a strong, an almost immediate impact on the field of hydrology. Here was somebody who was tackling the modeling of overland flow with the scientific standards of fluid mechanics. At the same time, finally somebody had

  14. Analog of the Peter-Weyl expansion for Lorentz group

    NASA Astrophysics Data System (ADS)

    Perlov, Leonid

    2015-11-01

    The expansion of a square integrable function on SL(2, C) into the sum of the principal series matrix coefficients with the specially selected representation parameters was recently used in the Loop Quantum Gravity [C. Rovelli and F. Vidotto, Covariant Loop Quantum Gravity: An Elementary Introduction to Quantum Gravity and Spinfoam Theory (Cambridge University Press, Cambridge, 2014) and C. Rovelli, Classical Quantum Gravity 28(11), 114005 (2011)]. In this paper, we prove that the sum used originally in the Loop Quantum Gravity: ∑ j = 0 ∞ ∑ |m| ≤ j ∑ |n| ≤ j Dj m , j n ( j , τ j ) ( g ) , where j, m, n ∈ Z, τ ∈ C is convergent to a function on SL(2, C); however, the limit is not a square integrable function; therefore, such sums cannot be used for the Peter-Weyl like expansion. We propose the alternative expansion and prove that for each fixed m: ∑ j = m ∞ D j m , j m ( j , τ j ) ( g ) is convergent and that the limit is a square integrable function on SL(2, C). We then prove the analog of the Peter-Weyl expansion: any ψ(g) ∈ L2(SL(2, C)) can be decomposed into the sum: ψ ( g ) = ∑ j = m ∞ j 2 ( 1 + τ 2 ) c j m m D j m , j m ( j , τ j ) ( g ) , with the Fourier coefficients c j m m = ∫ S L ( 2 , C ) ψ ( g ) Dj m , j m j , τ j ( g ) ¯ d g , g ∈ SL(2, C), τ ∈ C, τ ≠ i, - i, j, m ∈ Z, m is fixed. We also prove convergence of the sums ∑ j = |p| ∞ ∑ |m| ≤ j ∑ |n| ≤ j dp m /j 2 Dj m , j n ( j , τ j ) ( g ) , where d|p| m /j 2 = ( j + 1 ) /1 2 ∫ S U ( 2 ) ϕ ( u ) D|p| m /j 2 ( u ) ¯ d u is ϕ(u)'s Fourier transform and p, j, m, n ∈ Z, τ ∈ C, u ∈ SU(2), g ∈ SL(2, C), thus establishing the map between the square integrable functions on SU(2) and the space of the functions on SL(2, C). Such maps were first used in Rovelli [Class. Quant. Grav. 28, 11 (2011)].

  15. Reflections on Peter Slezak and the 'Sociology of Scientific Knowledge`

    NASA Astrophysics Data System (ADS)

    Suchting, W. A.

    The paper examines central parts of the first of two papers in this journal by Peter Slezak criticising sociology of scientific knowledge and also considers, independently, some of the main philosophical issues raised by the sociologists of science, in particular David Bloor. The general conclusion is that each account alludes to different and crucial aspects of the nature of knowledge without, severally or jointly, being able to theorise them adequately. The appendix contains epistemological theses central to a more adequate theory of scientific knowledge.... our Histories of six Thousand Moons make no Mention of any other, than the two great Empires of Lilliput and Blefuscu. Which mighty Powers have ... been engaged in a most obstinate War for six and thirty Moons past. It began upon the following Occasion. It is allowed on all Hands, that the primitive Way of breaking Eggs before we eat them, was upon the larger End: But ... the Emperor [of Lilliput] ... published an Edict, commanding all his Subjects, upon great Penalties, to break the smaller End of their Eggs. The People so resented this Law, that ... there have been six Rebellions raised on that Account ... These civil Commotions were constantly fomented by the Monarchs of Blefuscu ... It is computed, that eleven Thousand have, at several Times, suffered Death, rather than break Eggs at the smaller End. Many hundred large Volumes have published upon this Controversy ...

  16. Becoming a peter pan: omnipotence, dependency and the Ferenczian child.

    PubMed

    Bar-Haim, Shaul

    2015-03-01

    The aim of this paper is to provide a short history of the changes in Ferenczi's concept of early childhood, during the two decade period, 1913-1932. Initially, Ferenczi mainly emphasized children's feelings of omnipotence, which enable them to perceive themselves as strong, independent and capable human beings. By the mid-1920s, however, he felt that his earlier work did not give a good account of what comes after the stage of omnipotence, and that it did not adequately describe the difficulties in the transition from pleasure to reality principles. However, in his Clinical Diary, Ferenczi became fully aware of how fragile and insecure children are, and therefore how dangerous-yet necessary-it is for them to abandon the "stage of omnipotence" and to gain a "sense of reality". For Ferenczi, traumatized children are children who had not been loved in their early childhood, and therefore could not develop the capacity to make the journey from pleasure principle to that of reality. It will be suggested that a paradigmatic example for this kind of child is Peter Pan.

  17. Peter Agre, 2003 Nobel Prize winner in chemistry.

    PubMed

    Knepper, Mark A; Nielsen, Soren

    2004-04-01

    Peter C. Agre, an American Society of Nephrology member, is the recipient of the 2003 Nobel Prize in Chemistry for his discovery of the aquaporin water channels. The function of many cells requires that water move rapidly into and out of them. There was only indirect evidence that proteinaceous channels provide this vital activity until Agre and colleagues purified aquaporin-1 from human erythrocytes and reported its cDNA sequence. They proved that aquaporin-1 is a specific water channel by cRNA expression studies in Xenopus oocytes and by functional reconstitution of transport activity in liposomes after the incorporation of the purified protein. These findings sparked a veritable explosion of work that affects several long-standing areas of investigation such as the biophysics of water permeation across cell membranes, the structural biology of integral membrane proteins, the physiology of fluid transport in the kidney and other organs, and the pathophysiological basis of inherited and acquired disorders of water balance. Agre's discovery of the first water channel has spurred a revolution in animal and plant physiology and in medicine.

  18. Treatment of von Willebrand Disease.

    PubMed

    Curnow, Jennifer; Pasalic, Leonardo; Favaloro, Emmanuel J

    2016-03-01

    Congenital von Willebrand disease (VWD) and acquired von Willebrand syndrome (AVWS) reflect conditions caused by von Willebrand factor (VWF) deficiency and/or defects. VWD is the most common inherited bleeding disorder and AVWS arises from a variety of causes. Since VWF stabilizes and protects factor VIII (FVIII) in the circulation, this is also reduced in many patients with VWD. The treatment of VWD and AVWS therefore primarily entails replacement of VWF, and sometimes FVIII, to protect against bleeding. This may entail the use of VWF concentrates (currently plasma-derived) and/or FVIII concentrates (currently plasma-derived or more increasingly recombinant forms), and/or desmopressin to release endogenous VWF in subgroups of patients. For AVWS additional treatment of the underlying condition is also required. Adjunct therapies include antifibrinolytics. Globally, various formulations exist for both VWF and FVIII concentrates and are differentially available based on manufacturer marketing or regulatory approvals/clearances in different geographies. Also, guidelines for treatment of VWD vary for different localities and recombinant VWF is undergoing clinical trials. The current review provides an overview of the treatment of VWD as currently practiced in developed countries, and also provides a glimpse towards the future.

  19. Science Matters Podcast: Questions and Answers with EPA's Dr. Peter Grevatt

    EPA Pesticide Factsheets

    Listen to a podcast with Dr. Peter Grevatt, the director of EPA's Office of Children's Health Protection, as he answers questions about children's health, or read some of the highlights from the conversation here.

  20. Romantic Resonances in the Rhetoric of Peter Elbow's "Writing Without Teachers."

    ERIC Educational Resources Information Center

    Yager, Kristi

    1996-01-01

    Seeks to uncover the historical roots within English Romanticism of Peter Elbow's thinking in order to show the depth and complexity of his assumptions about writing. Implicitly refutes charges questioning the intellectual credibility of Elbow's work. (TB)

  1. 1. Historic American Buildings Survey, Peter Britt, Photographer, ca.1886, From ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey, Peter Britt, Photographer, ca.1886, From Britt Estate Collection SOUTHWEST ELEVATION (PRIOR TO SECOND STORY ADDITION). - Britt House, 201 South First Street, Jacksonville, Jackson County, OR

  2. Romantic Resonances in the Rhetoric of Peter Elbow's "Writing Without Teachers."

    ERIC Educational Resources Information Center

    Yager, Kristi

    1996-01-01

    Seeks to uncover the historical roots within English Romanticism of Peter Elbow's thinking in order to show the depth and complexity of his assumptions about writing. Implicitly refutes charges questioning the intellectual credibility of Elbow's work. (TB)

  3. Dr. von Braun Briefing Walt Disney

    NASA Technical Reports Server (NTRS)

    1965-01-01

    Dr. von Braun began his association with Walt Disney in the 1950s when the rocket scientist appeared in three Disney television productions related to the exploration of space. Years later, Dr. von Braun invited Disney and his associates to tour the Marshall Space Flight Center (MSFC) in Huntsville, Alabama. This photograph is dated April 13, 1965. From left are R.J. Schwinghamer from the MSFC, Disney, B.J. Bernight, and Dr. von Braun.

  4. Dr. von Braun Briefing Walt Disney

    NASA Technical Reports Server (NTRS)

    1965-01-01

    Dr. von Braun began his association with Walt Disney in the 1950s when the rocket scientist appeared in three Disney television productions related to the exploration of space. Years later, Dr. von Braun invited Disney and his associates to tour the Marshall Space Flight Center (MSFC) in Huntsville, Alabama. This photograph is dated April 13, 1965. From left are R.J. Schwinghamer from the MSFC, Disney, B.J. Bernight, and Dr. von Braun.

  5. Nichtlineare Rauschmodellierung von LC Tank VCOs

    NASA Astrophysics Data System (ADS)

    Thiessen, T.; Bremer, J.-K.; Mathis, W.

    2008-05-01

    Im Rahmen dieser Arbeit wird ein alternativer Ansatz zur Phasenrauschoptimierung von LC-Tank Oszillatoren (VCOs) unter Verwendung stochastischer Differentialgleichungen vorgestellt. Zunächst werden die linearen Ansätze von Leeson, Hajimiri und Lee analysiert und bewertet. Danach wird ein Konzept vorgestellt, mit dem man die Rauscheigenschaften von VCOs auf der Grundlage stochastischer Differentialgleichungen und Fokker-Planck-Gleichungen untersuchen kann. Ziel dieser Arbeit ist eine Beschreibung des Phasenrauschens auf der Basis einer nichtlinearen Rauschmodellierung, welche Parameter eines VCOs für eine Optimierung beinhaltet. Es wurde ein Matlab-Tool erstellt und die Funktionalität anhand von Simulationen verifiziert.

  6. Reflexionseigenschaften von Windenergieanlagen im Funkfeld von Funknavigations- und Radarsystemen

    NASA Astrophysics Data System (ADS)

    Sandmann, S.; Divanbeigi, S.; Garbe, H.

    2015-11-01

    Die hier behandelte Untersuchung befasst sich mit den Störungen des elektrischen Feldes einer Doppler Very High Frequency Omnidirectional Radio Range Navigationsanlage (DVOR) in der Gegenwart von Windenergieanlagen (WEA). Hierfür wird die Feldstärke auf 25 konzentrischen Kreisbahnen, sog. Orbit Flights verschiedener Höhen und mit verschiedenen Radien rund um die DVOR-Anlage numerisch simuliert. Insbesondere werden die Einflüsse diverser Parameter der WEA wie deren Anzahl, Position, Rotorwinkel, Turmhöhe und Rotordurchmesser auf die Feldverteilung herausgestellt, sowie die Anwendbarkeit der Simulationsmethode Physical Optics (PO) durch Vergleich der Simulationsergebnisse mit denen der Multi Level Fast Multipol Method (MLFMM) untersucht.

  7. Sophus Peter Tromholt: an outstanding pioneer in auroral research

    NASA Astrophysics Data System (ADS)

    Moss, K.; Stauning, P.

    2012-03-01

    The Danish school teacher Sophus Peter Tromholt (1851-1896) was self-taught in physics, astronomy, and auroral sciences. Still, he was one of the brightest auroral researchers of the 19th century. He was the first scientist ever to organize and analyse correlated auroral observations over a wide area (entire Scandinavia) moving away from incomplete localized observations. Tromholt documented the relation between auroras and sunspots and demonstrated the daily, seasonal and solar cycle-related variations in high-latitude auroral occurrence frequencies. Thus, Tromholt was the first ever to deduce from auroral observations the variations associated with what is now known as the auroral oval termed so by Khorosheva (1962) and Feldstein (1963) more than 80 yr later. He made reliable and accurate estimates of the heights of auroras several decades before this important issue was finally settled through Størmer's brilliant photographic technique. In addition to his three major scientific works (Tromholt, 1880a, 1882a, and 1885a), he wrote numerous short science notes and made huge efforts to collect historical auroral observations (Tromholt, 1898). Furthermore, Tromholt wrote a large number of popular science articles in newspapers and journals and made lecture tours all over Scandinavia and Germany, contributing to enhance the public educational level and awareness. He devoted most of his life to auroral research but as a self-taught scientist, he received little acclaim within the contemporary academic scientific society. With his non-academic background, trained at a college of education - not a university - he was never offered a position at a university or a research institution. However, Sophus Tromholt was an outstanding pioneer in auroral research.

  8. Ordovician conodonts and stratigraphy of the ST. Peter sandstone and glen wood shale, central United States

    USGS Publications Warehouse

    Witzke, B.J.; Metzger, R.A.

    2005-01-01

    The age of the St. Peter Sandstone in the central and northern Midcontinent has long been considered equivocal because of the general absence of biostratigraphically useful fossils. Conodonts recovered from the St. Peter Sandstone in Iowa, Minnesota, Nebraska, and Kansas for this study help place some age constraints on this renowned formation in its northern and western extent. Faunas from the lower St. Peter include Phragmodus flexuosus, Cahabagnathus sp., and Leptochirognathus sp., and a late Whiterockian (Chazyan) correlation is indicated. Juvenile or immature elements of P. flexuosus from these collections show morphologies trending toward P. cognitus and P. inflexus, and paedomorphic derivation of these latter species is proposed. Diverse assemblages of hyaline forms also occur in the St. Peter strata (Erismodus spp., Erraticodon sp., Curtognathus sp., Coleodus sp., Archeognathus sp., Stereoconus sp., others) along with various albid elements (Plectodina sp., Eoplacognathus sp., others). The overlying Glenwood Shale contains abundant conodonts dominated by Phragmodus cognitus, Erismodus sp., and Chirognathus duodactylus, and the fauna is interpreted as an early Mohawkian (Blackriveran) association. Certain thin shale units in the St. Peter-Glenwood succession represent condensed intervals, in part reflected by their exceptionally high conodont abundances. Some organic-rich phosphatic shale units in the lower St. Peter of western Iowa have produced equivalent yields of tens of thousands of conodonts per kilogram, and many Glenwood Shale samples yield thousands of conodonts per kilogram. Previous depositional models have proposed that the St. Peter is primarily a succession of littoral and nearshore facies forming a broadly diachronous transgressive sheet sand. However, broad-scale diachroneity cannot be demonstrated with available biostratigraphic control. The recognition of condensed marine shale units, phosphorites, ironstones, and pyritic hardgrounds in the

  9. Current management of von Willebrand disease and von Willebrand syndrome.

    PubMed

    Stone, Marc E; Mazzeffi, Michael; Derham, Jeffrey; Korshin, Andre

    2014-06-01

    Anesthesiologists frequently care for patients with altered hemostasis and coagulation. Where a clear history of familial and personal bleeding exists, a thoughtful plan can be developed in advance to manage the issue perioperatively. However, in some cases, it may not be known that the patient has a disorder until excessive bleeding is noted during or after surgery. Recognition of the issue and appropriate targeted therapy are the keys to successful management. With an estimated prevalence approaching 1% of the population, von Willebrand disease (vWD) is the most common hereditary bleeding diathesis, but the estimated prevalence of acquired vWD (often termed von Willebrand syndrome or vWS) is now believed to be significantly higher, especially in patients with malignancies, autoimmune diseases, cardiac valvular lesions, and in patients on mechanical circulatory support devices. Acquired vWD may also occur with certain medications. The mainstay of the diagnosis of vWD is laboratory testing. Preoperative clinical assessment and a high level of suspicion are often effective to alert the anesthesiologist to the possibility of vWS, thus allowing for appropriate testing and potential prophylaxis in elective situations, as well as appropriately targeted therapy of unexpected bleeding when a hemostatic derangement was not anticipated preoperatively.

  10. Von Karman Streets Chaotic Simulation

    NASA Astrophysics Data System (ADS)

    Skiadas, C. H.

    In this paper we model and simulate the so-called Von Karman Streets, a characteristic form of turbulent (vortex) flow that appears in small or large systems. Very interesting examples are the large turbulent formations in the sea or in the clouds that have been viewed and photographed from the space (from satellites). The modeling approach is based on the Rotation-Reflection-Translation theory developed in the recent book [1]. The related theory was already applied in various fields and especially in flows.

  11. Dr. Wernher Von Braun greeting dignitaries.

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. Wernher Von Braun, left, greets vice president Spiro T. Agnew in the Launch Control Center for the Apollo 14 mission. Between Dr. Von Braun and Mr. Agnew are their Royal Highnesses, The Prince and Princess of Spain. The royal visitors greeted the launch control team in th enter after the launch of Apollo 14.

  12. Dr. von Braun Tries Out the NBS

    NASA Technical Reports Server (NTRS)

    1967-01-01

    Marshall Space Flight Center (MSFC) Director, Dr. von Braun, is shown fitted with suit and diving equipment as he prepares for a tryout in the MSFC Neutral Buoyancy Simulator (NBS). Weighted to a neutrally buoyant condition, Dr. von Braun was able to perform tasks underwater which simulated weightless conditions found in space.

  13. Walt Disney and Dr. Wernher von Braun

    NASA Technical Reports Server (NTRS)

    1954-01-01

    Dr. Werhner von Braun, then Chief, Guided Missile Development Operation Division at Army Ballistic Missile Agency (ABMA) in Redstone Arsenal, Alabama, was visited by Walt Disney in 1954. In the 1950's, von Braun worked with Disney Studio as a technical director, making three films about space exploration for television. A model of the V-2 rocket is in background.

  14. Dr. Wernher von Braun Laid to Rest

    NASA Technical Reports Server (NTRS)

    1977-01-01

    Dr. Wernher von Braun served as Marshall Space Flight Center's first director from July 1, 1960 until January 27, 1970, when he was appointed NASA Deputy Associate Administrator for Planning. Following World War II, Dr. von Braun and his German colleagues arrived in the United States under Project Paper Clip to continue their rocket development work. In 1950, von Braun and his rocket team were transferred from Ft. Bliss, Texas to Huntsville, Alabama to work for the Army's rocket program at Redstone Arsenal and later, NASA's Marshall Space Flight Center. Under von Braun's leadership, Marshall developed the Saturn V launch vehicle which took Apollo astronauts to the moon. Dr. von Braun died in Alexandria, Va., on June 16, 1977, seven years after his NASA appointment. This photo was taken at the site where he was laid to rest.

  15. Dr. Wernher von Braun In His Office

    NASA Technical Reports Server (NTRS)

    1964-01-01

    Dr. Wernher von Braun served as Marshall Space Flight Center's first director from July 1, 1960 until January 27, 1970, when he was appointed NASA Deputy Associate Administrator for Planning. Following World War II, Dr. von Braun and his German colleagues arrived in the United States under Project Paperclip to continue their rocket development work. In 1950, von Braun and his rocket team were transferred from Ft. Bliss, Texas to Huntsville, Alabama to work for the Army's rocket program at Redstone Arsenal and later, NASA's Marshall Space Flight Center. Under von Braun's leadership, Marshall developed the Saturn V launch vehicle which took Apollo astronauts to the moon. This photo depicts von Braun in his office at MSFC.

  16. Clearance of von Willebrand factor.

    PubMed

    Denis, Cécile V; Christophe, Olivier D; Oortwijn, Beatrijs D; Lenting, Peter J

    2008-02-01

    The life cycle of von Willebrand factor (VWF) comprises a number of distinct steps, ranging from the controlled expression of the VWF gene in endothelial cells and megakaryocytes to the removal of VWF from the circulation. The various aspects of VWF clearance have been the objects of intense research in the last few years, stimulated by observations that VWF clearance is a relatively common component of the pathogenesis of type 1 von Willebrand disease (VWD). Moreover, improving the survival of VWF is now considered as a viable therapeutic strategy to prolong the half-life of factor VIII in order to optimise treatment of haemophilia A. The present review aims to provide an overview of recent findings with regard to the molecular basis of VWF clearance. A number of parameters have been identified that influence VWF clearance, including its glycosylation profile and a number of VWF missense mutations. In addition, in-vivo studies have been used to identify cells that contribute to the catabolism of VWF, providing a starting point for the identification of receptors that mediate the cellular uptake of VWF. Finally, we discuss recent data describing chemically modification of VWF as an approach to prolong the half-life of the VWF/FVIII complex.

  17. Alloantibodies in von Willebrand disease.

    PubMed

    James, Paula D; Lillicrap, David; Mannucci, Pier M

    2013-08-01

    The development of alloantibodies against von Willebrand factor (VWF) represents a rare but serious complication of treatment of von Willebrand disease (VWD), occurring in ~5% to 10% of type 3 VWD patients. Affected patients can present with a range of symptoms, including lack or loss of hemostatic response to infused VWF concentrates up to anaphylactic reactions in rare cases. It is classically reported in multitransfused patients and occurs most frequently in patients with partial or complete VWF gene deletions. A positive family history of anti-VWF antibodies also appears to be a risk factor. There is a lack of standardization of laboratory methods for antibody identification and characterization. Issues of variability in laboratory approaches as well as the rarity of the complication act as a barrier to future studies. Recombinant factor VIII as well as bypassing agents and immune tolerance have been reported as effective treatments; however, aside from case reports, little exists in the literature to guide management. The imminent clinical availability of recombinant VWF has prompted a resurgence of interest in this area. Additional study is warranted to address the deficiencies in our understanding of this treatment complication.

  18. [The veterinary pharmacopoeia of Peter Bodmer, blacksmith and cattle doctor in Därligen 1836].

    PubMed

    Kalbermatter, T

    2006-01-01

    The manuscript entitled "My pharmacopoeia Peter Bodmer in Därligen--1836" [Arzeneybuch mein Peter Bodmer in Därligen pro. 1836] contains a collection of a total of 227 remedies for the treatment of cattle, horses, pigs and human beings. The author Peter Bodmer was born on 15 November 1811 in Därligen on the shores of Lake Thun and worked as a smith and a cattle doctor. The manuscript cannot offer a full overview of the therapeutic possibilities in veterinary medicine at that time. The remedies mainly describe the peroral dispensing of herbal preparations. The use of medicinal plants, however, would only partially measure up to modern phytotherapy. Bodmer's manuscript provides a certain insight into the traditional herbal folk remedies used on animals and humans in the rural Bernese Oberland at that time.

  19. Anterior segment dysgenesis (Peters' anomaly) in two snow leopard (Panthera uncia) cubs.

    PubMed

    Hamoudi, Hassan; Rudnick, Jens-Christian; Prause, Jan U; Tauscher, Kerstin; Breithaupt, Angele; Teifke, Jens P; Heegaard, Steffen

    2013-07-01

    Two sibling snow leopards, a male and a female, with bilateral anterior segment dysgenesis (ASD), are reported. Both snow leopards also had colobomas of both upper eyelids. All eyes exhibited a central corneal opacity associated with a defect in posterior corneal stroma, endothelium and Descemet's membrane. Iris strands were present attached to the termination of Descemet's membrane and to the periphery of the posterior corneal defect. The iris was hypoplastic, and cataract was present in all four eyes. The left eye of the female was microphthalmic, with no trabecular meshwork and with persistent remnant of the hyaloid artery. The male had hydrocephalus and thus some of the features of Peters' plus syndrome (Peters' anomaly in addition to systemic malformations). The histological findings in the eyes of these snow leopard siblings are identical with those described in humans with Peters' anomaly.

  20. The 2009 Lindau Nobel Laureate Meeting: Peter Agre, Chemistry 2003

    PubMed Central

    Agre, Peter

    2009-01-01

    Peter Agre, born in 1949 in Northfield Minnesota, shared the 2003 Nobel Prize in Chemistry with Roderick MacKinnon for his discovery of aquaporins, the channel proteins that allow water to cross the cell membrane. Agre's interest medicine was inspired by the humanitarian efforts of the Medical Missionary program run by the Norwegians of his home community in Minnesota. Hoping to provide new treatments for diseases affecting the poor, he joined a cholera laboratory during medical school at Johns Hopkins. He found that he enjoyed biomedical research, and continued his laboratory studies for an additional year after medical school. Agre completed his clinical training at Case Western Hospitals of Cleveland and the University of North Carolina, and returned to Johns Hopkins in 1981. There, his serendipitous discovery of aquaporins was made while pursuing the identity of the Rhesus (Rh) antigen. For a century, physiologists and biophysicists had been trying to understand the mechanism by which fluid passed across the cell's plasma membrane. Biophysical evidence indicated a limit to passive diffusion of water, suggesting the existence of another mechanism for water transport across the membrane. The putative "water channel," however, could not be identified. In 1988, while attempting to purify the 30kDa Rh protein, Agre and colleagues began investigating a 28 kDa contaminant that they believed to be a proteolytic fragment of the Rh protein. Subsequent studies over the next 3-4 years revealed that the contaminant was a membrane-spanning oligomeric protein, unrelated to the Rh antigen, and that it was highly abundant in renal tubules and red blood cells. Still, they could not assign a function to it. The breakthrough came following a visit with his friend and former mentor John Parker. After Agre described the properties of the mysterious 28 kDa protein, Parker suggested that it might be the long-sought-after water channel. Agre and colleagues tested this idea by

  1. The 2009 Lindau Nobel Laureate Meeting: Peter Agre, Chemistry 2003.

    PubMed

    Agre, Peter

    2009-12-09

    Peter Agre, born in 1949 in Northfield Minnesota, shared the 2003 Nobel Prize in Chemistry with Roderick MacKinnon for his discovery of aquaporins, the channel proteins that allow water to cross the cell membrane. Agre's interest medicine was inspired by the humanitarian efforts of the Medical Missionary program run by the Norwegians of his home community in Minnesota. Hoping to provide new treatments for diseases affecting the poor, he joined a cholera laboratory during medical school at Johns Hopkins. He found that he enjoyed biomedical research, and continued his laboratory studies for an additional year after medical school. Agre completed his clinical training at Case Western Hospitals of Cleveland and the University of North Carolina, and returned to Johns Hopkins in 1981. There, his serendipitous discovery of aquaporins was made while pursuing the identity of the Rhesus (Rh) antigen. For a century, physiologists and biophysicists had been trying to understand the mechanism by which fluid passed across the cell's plasma membrane. Biophysical evidence indicated a limit to passive diffusion of water, suggesting the existence of another mechanism for water transport across the membrane. The putative "water channel," however, could not be identified. In 1988, while attempting to purify the 30 kDa Rh protein, Agre and colleagues began investigating a 28 kDa contaminant that they believed to be a proteolytic fragment of the Rh protein. Subsequent studies over the next 3-4 years revealed that the contaminant was a membrane-spanning oligomeric protein, unrelated to the Rh antigen, and that it was highly abundant in renal tubules and red blood cells. Still, they could not assign a function to it. The breakthrough came following a visit with his friend and former mentor John Parker. After Agre described the properties of the mysterious 28 kDa protein, Parker suggested that it might be the long-sought-after water channel. Agre and colleagues tested this idea by

  2. A double commutant theorem for Murray–von Neumann algebras

    PubMed Central

    Liu, Zhe

    2012-01-01

    Murray–von Neumann algebras are algebras of operators affiliated with finite von Neumann algebras. In this article, we study commutativity and affiliation of self-adjoint operators (possibly unbounded). We show that a maximal abelian self-adjoint subalgebra of the Murray–von Neumann algebra associated with a finite von Neumann algebra is the Murray–von Neumann algebra , where is a maximal abelian self-adjoint subalgebra of and, in addition, is . We also prove that the Murray–von Neumann algebra with the center of is the center of the Murray–von Neumann algebra . Von Neumann’s celebrated double commutant theorem characterizes von Neumann algebras as those for which , where , the commutant of , is the set of bounded operators on the Hilbert space that commute with all operators in . At the end of this article, we present a double commutant theorem for Murray–von Neumann algebras. PMID:22543165

  3. Indikatorenbasierte Bewertung von Entwurfsentscheidungen auf Systemebene

    NASA Astrophysics Data System (ADS)

    Freier, M.; Wenzler, A.; Mayer, T.; Gerlach, J.; Rosenstiel, W.

    2013-07-01

    Bei dem Entwurf von anwendungsspezifischen integrierten Schaltungen muss ein Entwickler zusätzliche Funktionen integrieren und die zunehmende Komplexität bewältigen. Für die Reduzierung der Kosten bleibt weiterhin die Verkürzung der benötigten Entwicklungszeit ein Ziel. Ein entscheidender Faktor dabei ist die zuverlässige Absicherung von Entwurfsentscheidungen in einer frühen Entwurfsphase. In der vorliegenden Arbeit wird eine Methode vorgestellt, die eine Bewertung von Entwurfsentscheidungen bei Systemmodellen mittels automatisch ermittelter Indikatoren ermöglichen soll. Die Systemmodelle können mit der Entwurfsumgebung MATLAB/Simulink oder in SystemC beschrieben sein.

  4. Von Hippel-Lindau disease.

    PubMed

    Maher, Eamonn R

    2004-12-01

    Germline mutations in the VHL tumour suppressor gene may cause a variety of phenotypes including von Hippel-Lindau (VHL) disease, familial phaeochromocytoma and inherited polycythaemia. VHL disease is a multisystem familial cancer syndrome and is the commonest cause of familial renal cell carcinoma (RCC). VHL disease provides a paradigm for illustrating how studies of a rare familial cancer syndrome can produce advances in clinical medicin and important insights into basic biological processes. Thus the identification of the VHL gene has improved the diagnosis and clinical management of VHL disease and provided insights into the pathogenesis of sporadic clear cell RCC. Functional investigations of the VHL gene product have provided novel information on how cells sense oxygen and the role of hypoxia-response pathways in human tumourigenesis. Such information offers prospects of novel therapeutic interventions for VHL disease and common cancers including RCC.

  5. The Digital Von Fahrenheid Pyramid

    NASA Astrophysics Data System (ADS)

    Bura, M.; Janowski, J.; Wężyk, P.; Zięba, K.

    2017-08-01

    3D Scanners Lab from Digital Humanities Laboratory at the University of Warsaw initiated the scientific project, the purpose of which was to call attention to systematically penetrated and devastated pyramid-shaped tomb from the XVIII/XIX century, of family von Fahrenheid in Rapa in Banie Mazurskie commune (NE Poland). By conducting a series of non-invasive studies, such as 3D inventory using terrestrial laser scanning (TLS), thermal imaging, georadar measurements (around and inside the tomb) and anthropological research of mummified remains as well - the complete dataset was collected. Through the integration of terrestrial (TLS) and airborne laser scanning (ALS) authors managed to analyse the surroundings of Fahrenheid pyriamid and influence of some objects (like trees) on the condition and visibility of the Pyramids in the landscape.

  6. 8q21.11 microdeletion in two patients with syndromic peters anomaly.

    PubMed

    Happ, Hannah; Schilter, Kala F; Weh, Eric; Reis, Linda M; Semina, Elena V

    2016-09-01

    Peters anomaly is a form of anterior segment dysgenesis characterized by central ocular opacity and corneo-lenticular adhesions. Isolated and syndromic Peters anomaly can be observed and demonstrate significant genetic heterogeneity. We report the identification of overlapping 8q21.11 deletions in two patients with syndromic Peters anomaly via whole exome sequencing and chromosomal microarray analyses. Microdeletions of 8q21.11 were recently reported in 10 patients with highly variable phenotypes involving craniofacial features, ptosis, intellectual disability, abnormalities of the hands/feet and other defects; sclerocornea and/or microphthalmia were reported in three cases. The two additional cases presented in this report expand the phenotypic spectrum of 8q21.11 microdeletions to include Peters anomaly (seen in both patients) and persistent primary dentition (seen in one patient with a larger deletion). The two novel deletions include the ZFHX4 and PEX2 genes, which were also affected in all three previous cases involving ocular anomalies. Screening of the remaining alleles of ZFHX4 and PEX2 did not identify any additional likely pathogenic variants in either patient, suggesting a dominant mechanism (haploinsufficiency) for the identified deletion. This report provides further insight into the phenotypes associated with 8q21.11 deletions and, for the first time, reports Peters anomaly as an additional ocular feature; screening for copy number variations of the 8q21.11 region should be considered in patients with Peters anomaly and related syndromic features. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  7. Optimising keratoplasty for Peters' anomaly in infants using spectral-domain optical coherence tomography.

    PubMed

    Hong, Jiaxu; Yang, Yujing; Cursiefen, Claus; Mashaghi, Alireza; Wu, Dan; Liu, Zuguo; Sun, Xinghuai; Dana, Reza; Xu, Jianjiang

    2017-06-01

    To present in vivo anterior segment optical coherence tomography (OCT) features of infants with Peters' anomaly obtained during presurgical examination under general anaesthesia, and to evaluate the impact of OCT features on surgical decision making. This is a single-centre, consecutive, observational case series including 44 eyes of 27 infants with Peters' anomaly (5-18 months) undergoing keratoplasty. Medical records of patients were reviewed retrospectively. Clinical features and OCT findings, along with their impact on surgical decision-making were analysed. Of 27 patients, 10 had unilateral and 17 had bilateral disease. Two patients with mild disease (three eyes) had a posterior corneal defect with leukoma (2/27, 7.4%). Twenty patients (32 eyes) with iridocorneal adhesions were classified as having moderate Peters' anomaly (20/27, 74.1%) and five patients (nine eyes) with lenticulocorneal adhesions were classified as having severe Peters' anomaly (5/27, 18.5%). The range of angle closure, anterior chamber depth and maximum iridocorneal adhesion length (all p<0.001) were significantly different among groups, indicating that they might serve as novel OCT parameters for assessing the severity of Peters' anomaly. The surgical approach in seven patients (21.2%) was altered in response to intraoperative OCT findings, which provided information regarding the anatomical structure of the anterior chamber not provided by the surgical microscope. The use of OCT prevented unnecessary cataract surgeries in five patients. Our study showed that information gained from OCT under anaesthesia allows surgeons to classify type and severity of Peters' anomaly and supports surgical decision making. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  8. A very Freudian affair: Erich Fromm, Peter Swales and the future of psychoanalytic historiography.

    PubMed

    Burston, Daniel

    2008-01-01

    Despite steadfast denials by Ernest Jones, Peter Gay and Paul Roazen (among others), a recent discovery by Franz Maciejewski renders it reasonably certain that Freud had an affair with his sister-in-law, Minna Bernays. While this discovery vindicates certain claims made by the controversial Freud scholar, Peter Swales, other claims of his vis-a-vis Freud's personality and ideas are open to doubt. Meanwhile, the reception of Swales's ideas, and indeed the whole controversy about Freud's love life, provide ample confirmation of many of Erich Fromm's prescient theses about Freud's personality and the politics and historiography of psychoanalysis.

  9. Interview with Peter McLaren, on His Work, on His Visit to Turkey and on Ongoing Popular Struggles

    ERIC Educational Resources Information Center

    Fassbinder, Samuel Day

    2013-01-01

    Peter McLaren is, as the back cover of his (2005) Capitalists & Conquerors: a critical pedagogy against empire says, "professor of urban education at the Graduate School of Education and Information Studies at the University of California, Los Angeles". Peter is also now a Distinguished Fellow in Critical Studies at Chapman…

  10. Is R. S. Peters' Way of Mentioning Women in His Texts Detrimental to Philosophy of Education? Some Considerations and Questions

    ERIC Educational Resources Information Center

    Lees, Helen E.

    2012-01-01

    Discussion in this article considers the unfortunate way R.S. Peters made mention of women when it was pertinent to his argumentation: portraying them, directly or indirectly, as abuse-able (murderable), deficient, aberrant, clueless and inconstant. It is argued that the high profile and esteem within which Peter's texts are held within philosophy…

  11. Is R. S. Peters' Way of Mentioning Women in His Texts Detrimental to Philosophy of Education? Some Considerations and Questions

    ERIC Educational Resources Information Center

    Lees, Helen E.

    2012-01-01

    Discussion in this article considers the unfortunate way R.S. Peters made mention of women when it was pertinent to his argumentation: portraying them, directly or indirectly, as abuse-able (murderable), deficient, aberrant, clueless and inconstant. It is argued that the high profile and esteem within which Peter's texts are held within philosophy…

  12. Interview with Peter McLaren, on His Work, on His Visit to Turkey and on Ongoing Popular Struggles

    ERIC Educational Resources Information Center

    Fassbinder, Samuel Day

    2013-01-01

    Peter McLaren is, as the back cover of his (2005) Capitalists & Conquerors: a critical pedagogy against empire says, "professor of urban education at the Graduate School of Education and Information Studies at the University of California, Los Angeles". Peter is also now a Distinguished Fellow in Critical Studies at Chapman…

  13. Theories of Power, Poverty, and Law: In Commemoration of the Contributions of Peter Bachrach--Empowerment and Poverty

    ERIC Educational Resources Information Center

    Levi, Margaret

    2010-01-01

    My subject is the way Peter Bachrach addressed the question of poverty. But given that I was his student and research assistant and that I am a political scientist largely because of him, it is impossible to resist a few words about the experience of being in his classrooms. Peter was an inspiring teacher of politics. The substantive content of…

  14. Dr. von Braun With Management Team

    NASA Technical Reports Server (NTRS)

    1961-01-01

    Dr. von Braun is shown in this photograph, which was probably taken in the early 1960s, with members of his management team. Pictured from left to right are, Werner Kuers, Director of the Manufacturing Engineering Division; Dr. Walter Haeussermarn, Director of the Astrionics Division; Dr. William Mrazek, Propulsion and Vehicle Engineering Division; Dr. von Braun; Dieter Grau, Director of the Quality Assurance Division; Dr. Oswald Lange, Director of the Saturn Systems Office; and Erich Neubert , Associate Deputy Director for Research and Development.

  15. Childhood Picture of Dr. von Braun

    NASA Technical Reports Server (NTRS)

    1912-01-01

    This is a childhood picture of Dr. von Braun (center) with his brothers. Dr. Wernher von Braun was born in Wirsitz, Germany, March 23, 1912. His childhood dreams of marned space flight were fulfilled when giant Saturn rockets, developed under his direction at NASA's Marshall Space Flight Center, boosted the manned Apollo spacecraft to the Moon. His life was dedicated to expanding man's knowledge through the exploration of space.

  16. Childhood Picture of Dr. von Braun

    NASA Technical Reports Server (NTRS)

    1912-01-01

    This is a childhood picture of Dr. von Braun (center) with his brothers. Dr. Wernher von Braun was born in Wirsitz, Germany, March 23, 1912. His childhood dreams of marned space flight were fulfilled when giant Saturn rockets, developed under his direction at NASA's Marshall Space Flight Center, boosted the manned Apollo spacecraft to the Moon. His life was dedicated to expanding man's knowledge through the exploration of space.

  17. Renaturierung von Tagebaufolgeflächen

    NASA Astrophysics Data System (ADS)

    Tischew, Sabine

    Der Abbau von Rohstoffen im Tagebauverfahren bedingt einen tief greifenden Landschafts- und Strukturwandel in den betroffenen Regionen. In der Abbauphase hat vor allem der Braunkohleabbau mit den tagebauübergreifenden Grundwasserabsenkungstrichtern, der Zerstörung oder Beeinträchtigung von ausgedehnten naturnahen Auenökosystemen sowie Wäldern und Elementen der Kulturlandschaft aus der Sicht des Naturschutzes überwiegend negative landschaftsökologische Folgen. Vor allem der Eingriff in Ökosysteme mit langen Entwicklungszeiten (alte Wälder, Moore) oder in die Dynamik von Auensystemen ist nicht oder nur in sehr langen Zeiträumen wieder ausgleichbar. Für letztere ist auch langfristig die Durchgängigkeit für viele Tierarten (Arten der Fließgewässer) nicht wieder vollständig herstellbar. Oft ist es zudem schwierig, traditionelle Landnutzungen (z. B. Wanderschäferei, Nutzung von Streuobstwiesen) nach der langen Abbauphase wieder aufzugreifen. Es ist deshalb eine wichtige Aufgabe, nach dem Abbauprozess auf der Grundlage der vorhandenen Potenziale eine nachhaltige Entwicklung der Bergbaufolgelandschaft zu unterstützen und von den Betreibern des Abbaus und von den Sanierungsgesellschaften auch einzufordern (z. B. Bauer 1998).

  18. Why Was Peter Parley Popular? Lessons for the Social Studies Textbook Authors.

    ERIC Educational Resources Information Center

    Palmer, Jesse; And Others

    1991-01-01

    Examines the unpopularity of social studies among students. Suggests that the source of the problem may be found in textbooks. Discusses textbooks written by Samuel Griswold Goodrich, a.k.a. "Peter Parley," a nineteenth-century U.S. social studies textbook writer. Underscores his belief in using literature to connect social studies to…

  19. Samuel Griswold Goodrich, a.k.a. Peter Parley, Early American Geographer.

    ERIC Educational Resources Information Center

    Smith, Ben A.; Vining, James W.

    1991-01-01

    Examines the life and work of Samuel Griswold Goodrich who, writing under the name "Peter Parley," was one of the United States' most prolific geography textbook writers. Explains that Parley was among the nineteenth century's best known educational figures. Underscores Goodrich's profuse use of illustrations and personal writing style.…

  20. Approaching 21st Century Social Studies with 19th Century Wisdom: A Peter Parley Model.

    ERIC Educational Resources Information Center

    Davis, John C.; And Others

    Peter Parley (Samuel Griswold Goodrich) was the earliest writer of popular social studies books and magazines for children. His books were in print from 1828 through 1912 and sold over 12 million volumes. An annotated bibliography of 45 of his works located in the deGrummond Collection at the University of Southern Mississippi (Hattiesburg) is…

  1. R. S. Peters and J. H. Newman on the Aims of Education

    ERIC Educational Resources Information Center

    Ozolins, Janis T.

    2013-01-01

    R. S. Peters never explicitly talks about wisdom as being an aim of education. He does, however, in numerous places, emphasize that education is of the whole person and that, whatever else it might be about, it involves the development of knowledge and understanding. Being educated, he claims, is incompatible with being narrowly specialized.…

  2. Paradoxes of a Long Life Learning: An Exploration of Peter Jarvis's Contribution to Experiential Learning Theory

    ERIC Educational Resources Information Center

    Dyke, Martin

    2017-01-01

    The paper explores the work of Peter Jarvis related to learning with particular reference to his definitions of learning and his models of the learning process. This exploration will consider different approaches to experiential learning and demonstrate the contribution Jarvis has made, noting how his writing on the subject has changed over time.…

  3. "Operating on a Basis of Student Consent": Peter Medway's Work in "Finding a Language"

    ERIC Educational Resources Information Center

    Burgess, Tony

    2015-01-01

    Written nearly 40 years ago, Peter Medway's "Finding a Language" continues to be an arresting read, which offers a powerful vision of what might be possible in education. In this brief introduction, I set the work in context, referring to ideas that Pete engaged with and recalling a little of the times.

  4. The Possibilities of Transformation: Critical Research and Peter McLaren

    ERIC Educational Resources Information Center

    Porfilio, Brad J.

    2006-01-01

    The purpose of this paper is to unveil how Peter McLaren's revolutionary brand of pedagogy, multiculturalism, and research colored my two-year qualitative research study, which unearthed twenty White female future teachers' experiences and perceptions in relationship to computing technology and male-centered computing culture. His ideas positioned…

  5. Communicating Chemistry from "Molecules" to International Efforts: An Interview with Peter Atkins

    ERIC Educational Resources Information Center

    Cardellini, Liberato

    2008-01-01

    In this interview, Peter Atkins explains the deep motivations that compel him to sit at his desk at 6 AM writing books and textbooks. He discusses the four principal elements that help to make a chemistry textbook successful, including the secret ingredient. He also discusses the importance of problem solving, the interaction of multimedia, and…

  6. Between Fiction and Reality: Maps and Cartographic Logic in the Works of Peter Sís

    ERIC Educational Resources Information Center

    Cantavella, Anna Juan

    2017-01-01

    This article examines the use of maps in the works of Czech author-illustrator Peter Sís in order to consider the role that cartography plays in the construction of four of his biographical picturebooks: Follow the Dream: "The Story of Christopher Columbus" (2003/1991), "Starry Messenger: Galileo Galilei" (1996), "The Tree…

  7. The Peter Effect Revisited: Reading Habits and Attitudes of College Students

    ERIC Educational Resources Information Center

    Applegate, Anthony J.; Applegate, Mary DeKonty; Mercantini, Martha A.; McGeehan, Catherine M.; Cobb, Jeanne B.; DeBoy, Joanne R.; Modla, Virginia B.; Lewinski, Kimberly E.

    2014-01-01

    Certainly a primary goal of literacy education is the creation of avid, enthusiastic, and highly motivated readers. However, in this article revisiting the Peter Effect (Applegate & Applegate, 2004), researchers surveyed more than 1,000 college sophomores and found strikingly low levels of enthusiasm for reading. Only 46.6% of surveyed…

  8. Communicating Chemistry from "Molecules" to International Efforts: An Interview with Peter Atkins

    ERIC Educational Resources Information Center

    Cardellini, Liberato

    2008-01-01

    In this interview, Peter Atkins explains the deep motivations that compel him to sit at his desk at 6 AM writing books and textbooks. He discusses the four principal elements that help to make a chemistry textbook successful, including the secret ingredient. He also discusses the importance of problem solving, the interaction of multimedia, and…

  9. Respectability and Relevance: Reflections on Richard Peters and Analytic Philosophy of Education

    ERIC Educational Resources Information Center

    Snook, Ivan

    2013-01-01

    I argue that, after Dewey, Peters was the first modern philosopher of education to write material (in English) that was both philosophically respectable and relevant to the day-to-day concerns of teachers. Since then, some philosophers of education have remained (more or less) relevant but not really respectable while others have "taken off into…

  10. Michael Peters' Lyotardian Account of Postmodernism and Education: Some Epistemic Problems and Naturalistic Solutions

    ERIC Educational Resources Information Center

    Clark, John A.

    2006-01-01

    Postmodernism has established a significant hold in educational thought and some of the most important ideas are to be found in the writings of Michael Peters. This paper examines his postmodern stance and use of Lyotard's account of knowledge, and from a naturalist point of view raises a number of objections centred on science as a metanarrative,…

  11. A Pedagogy of Dealienation: A Case Study in the Application of Peter Berger's "The Sacred Canopy"

    ERIC Educational Resources Information Center

    Chance, J. Bradley

    2004-01-01

    This paper explores the use of Peter Berger's theory of religion and its features of alienation and dealienation to lead students to the critical awareness of the role that human beings play in the construction of social worlds, including most especially our religious worlds. After summarizing Berger's theory of the alienating and potentially…

  12. Education, Philosophy and Politics: The Selected Works of Michael A. Peters. World Library of Educationalists

    ERIC Educational Resources Information Center

    Peters, Michael A.

    2012-01-01

    In the World Library of Educationalists series, international experts themselves compile career-long collections of what they judge to be their finest pieces--extracts from books, key articles, salient research findings, major theoretical and/practical contributions--so the world can read them in a single manageable volume. Michael A. Peters has…

  13. Archaeological Monitoring of the St. Peter Street Floodgates Project, Orleans Parish, Louisiana

    DTIC Science & Technology

    1992-01-24

    the New Orleans Vieux Carre Historic District were monitored to insure that no significant cultural resources were adversely impacted. Construction...monitoring of the St. Peter Street Floodgates Project, Orleans Parish, Louisiana. Construction excavations with the New Orleans Vieux Carre Historic...Orleans Vieux Carre Historic District which became a National Historic Landmark in 1965 (Scope of Services). Archaeological monitoring of the construction

  14. Two Is the Beginning of the End: "Peter Pan" and the Doctrine of Reminiscence

    ERIC Educational Resources Information Center

    Hudson, Glenda A.

    2006-01-01

    This article considers J.M. Barrie's satirical treatment of the Platonic doctrine of reminiscence in "Peter Pan," and how Barrie's work both honors and undercuts it. It will first analyze the Platonic notion of the doctrine of reminiscence in Wordsworth's "Ode: Intimations of Immortality from Recollections of Early Childhood" (1807). It will then…

  15. John Peter Zenger and the Freedom of the Press: 250th Anniversary, 1735-1985.

    ERIC Educational Resources Information Center

    New York State Library, Albany.

    This booklet accompanies the New York State Library exhibit of material related to the trial of John Peter Zenger. This 1735 trial established the legal precedent giving juries the power to decide libel suits. Labeled "the germ of American freedom," the trial was an important step in the development of American concepts of free speech…

  16. Sandra Diane Knapp—Recipient of the 2008 Peter Raven Award

    USDA-ARS?s Scientific Manuscript database

    Dr. Sandra Knapp, Curator at Natural History Museum in London, is the 2009 recipient of the Peter Raven Award. This award is provided each year by the American Society of Plant Taxonomists to a plant systematist who has made exceptional efforts at outreach to nonscientists. This publication summariz...

  17. Victors and Victims in the Tales of "Peter Rabbit" and "Squirrel Nutkin."

    ERIC Educational Resources Information Center

    Frey, Charles

    1987-01-01

    Analyzes "Peter Rabbit" and "Squirrel Nutkin" by B. Potter as presenting images of boys who refuse to participate in food gathering rituals of their clan, preferring to challenge authority. Treats the stories as modern myths that admonish boys to have fun, but be prepared for the consequences of mischief. (SKC)

  18. Two Is the Beginning of the End: "Peter Pan" and the Doctrine of Reminiscence

    ERIC Educational Resources Information Center

    Hudson, Glenda A.

    2006-01-01

    This article considers J.M. Barrie's satirical treatment of the Platonic doctrine of reminiscence in "Peter Pan," and how Barrie's work both honors and undercuts it. It will first analyze the Platonic notion of the doctrine of reminiscence in Wordsworth's "Ode: Intimations of Immortality from Recollections of Early Childhood" (1807). It will then…

  19. Two Causes of Underachievement--The Scapegoat Phenomenon and the Peter Pan Syndrome. Part II.

    ERIC Educational Resources Information Center

    Grau, Phyllis Nelson

    1986-01-01

    Two profiles of underachievement are described: the Peter Pan Syndrome, characterized by irresponsibility, anxiety, loneliness, sex role conflict, and narcissism, and the scapegoating phenomenon, in which children acquire negative self-images from victimization experiences. Prognoses and recommendations for each are offered. (Author/CL)

  20. A Genealogical Analysis of Peter Arnold's Conceptual Account of Meaning in Movement, Sport and Physical Education

    ERIC Educational Resources Information Center

    Stolz, Steven A.; Thorburn, Malcolm

    2017-01-01

    We write as critical theorists who share an interest in how conceptions of physical education are taken forward in policy and practice. In this respect, we are particularly intrigued by Peter Arnold's conceptual account of meaning in movement, sport and physical education, and the subsequent ways in which his ideas have informed national…

  1. Behavioral Determinants of Drug Action: The Contributions of Peter B. Dews

    ERIC Educational Resources Information Center

    Barrett, James E.

    2006-01-01

    Peter B. Dews played a significant role in shaping the distinctive characteristics and defining the underlying principles of the discipline of behavioral pharmacology. His early and sophisticated use of schedules of reinforcement in the 1950s, incorporated from research in the experimental analysis of behavior and integrated into the discipline of…

  2. Michael Peters' Lyotardian Account of Postmodernism and Education: Some Epistemic Problems and Naturalistic Solutions

    ERIC Educational Resources Information Center

    Clark, John A.

    2006-01-01

    Postmodernism has established a significant hold in educational thought and some of the most important ideas are to be found in the writings of Michael Peters. This paper examines his postmodern stance and use of Lyotard's account of knowledge, and from a naturalist point of view raises a number of objections centred on science as a metanarrative,…

  3. R. S. Peters and J. H. Newman on the Aims of Education

    ERIC Educational Resources Information Center

    Ozolins, Janis T.

    2013-01-01

    R. S. Peters never explicitly talks about wisdom as being an aim of education. He does, however, in numerous places, emphasize that education is of the whole person and that, whatever else it might be about, it involves the development of knowledge and understanding. Being educated, he claims, is incompatible with being narrowly specialized.…

  4. Reason and Virtues: The Paradox of R. S. Peters on Moral Education

    ERIC Educational Resources Information Center

    Haydon, Graham

    2009-01-01

    This article examines the work of R. S. Peters on moral development and moral education, as represented in his papers collected under that name, pointing out that these writings have been relatively neglected. It approaches these writings through the lens of the "familiar story" that philosophical work on this topic switched during, roughly, the…

  5. How Relevant Is R. S. Peters' Conception of Education to Science Education?

    ERIC Educational Resources Information Center

    Hadzigeorgiou, Yannis; Stamatis, Panagiotis

    2017-01-01

    This paper discusses R. S. Peters' concept of education, particularly his notion of cognitive perspective and its relevance to school science education. In light of the problems inherent in any attempt to define the notion of scientific literacy, it is argued that the development of cognitive perspective can be considered an important, if not the…

  6. John Peter Zenger and the Freedom of the Press: 250th Anniversary, 1735-1985.

    ERIC Educational Resources Information Center

    New York State Library, Albany.

    This booklet accompanies the New York State Library exhibit of material related to the trial of John Peter Zenger. This 1735 trial established the legal precedent giving juries the power to decide libel suits. Labeled "the germ of American freedom," the trial was an important step in the development of American concepts of free speech…

  7. Education, Philosophy and Politics: The Selected Works of Michael A. Peters. World Library of Educationalists

    ERIC Educational Resources Information Center

    Peters, Michael A.

    2012-01-01

    In the World Library of Educationalists series, international experts themselves compile career-long collections of what they judge to be their finest pieces--extracts from books, key articles, salient research findings, major theoretical and/practical contributions--so the world can read them in a single manageable volume. Michael A. Peters has…

  8. Interview with Peter Samis and Mimi Michaelson, Authors of "Creating the Visitor-Centered Museum"

    ERIC Educational Resources Information Center

    Spero, Susan

    2017-01-01

    "Creating the Visitor-Centered Museum" offers insight into why and how 10 case study museums have transformed to serve the needs of their public. Susan Spero interviews authors Peter Samis and Mimi Michaelson about the purpose of the book, their case study choices, the key characteristics of visitor-centered institutions and their…

  9. Implications of R. S. Peters' Notion of "Cognitive Perspective" for Science Education

    ERIC Educational Resources Information Center

    Hadzigeorgiou, Yannis

    2017-01-01

    This paper discusses R.S. Peters' notion of "cognitive perspective," which, through careful reading, can be interpreted as a wider perspective resulting from an awareness of the relationships of one's knowledge and understanding to one's own life. This interpretation makes cognitive perspective a holistic notion akin to that of…

  10. Respectability and Relevance: Reflections on Richard Peters and Analytic Philosophy of Education

    ERIC Educational Resources Information Center

    Snook, Ivan

    2013-01-01

    I argue that, after Dewey, Peters was the first modern philosopher of education to write material (in English) that was both philosophically respectable and relevant to the day-to-day concerns of teachers. Since then, some philosophers of education have remained (more or less) relevant but not really respectable while others have "taken off into…

  11. 14. Photocopy of a photographca. 1902taken by A.W. Peters showing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Photocopy of a photograph--ca. 1902--taken by A.W. Peters showing Eastwood and his party surveying for the Big Creek Project. The surveying party is visible in the upper right corner. Courtesy Mr. Charles Allan Whitney. - Little Rock Creek Dam, Little Rock Creek, Littlerock, Los Angeles County, CA

  12. "Operating on a Basis of Student Consent": Peter Medway's Work in "Finding a Language"

    ERIC Educational Resources Information Center

    Burgess, Tony

    2015-01-01

    Written nearly 40 years ago, Peter Medway's "Finding a Language" continues to be an arresting read, which offers a powerful vision of what might be possible in education. In this brief introduction, I set the work in context, referring to ideas that Pete engaged with and recalling a little of the times.

  13. "Staying on Task": What Constitutes Classwork in Peter Medway's "Finding a Language"?

    ERIC Educational Resources Information Center

    Pangilinan, J. P.

    2015-01-01

    In "Finding a Language", Peter Medway addresses questions of central importance to English teaching--questions of curriculum and of pedagogy. How he addresses these questions provides a sharp contrast to the current orthodoxies of a rigidly prescriptive national curriculum and a closely monitored regime of objective-led, skills-based…

  14. The Authority of Truth: Religion and the John Peter Zenger Case.

    ERIC Educational Resources Information Center

    Nord, David Paul

    An appreciation of the religious milieu of the John Peter Zenger libel case of 1735 can help explain the nature of the Zenger defense as prepared by Alexander Hamilton, the meaning of the jury's verdict, and the ambiguous legacy of the trial for freedom of expression in the United States. In essence, the case was a disputation on "truth"…

  15. The Possibilities of Transformation: Critical Research and Peter McLaren

    ERIC Educational Resources Information Center

    Porfilio, Brad J.

    2006-01-01

    The purpose of this paper is to unveil how Peter McLaren's revolutionary brand of pedagogy, multiculturalism, and research colored my two-year qualitative research study, which unearthed twenty White female future teachers' experiences and perceptions in relationship to computing technology and male-centered computing culture. His ideas positioned…

  16. Peter Parley and His Way of Teaching Geography to Future Citizens.

    ERIC Educational Resources Information Center

    Smith, Ben A.; Vining, James W.

    Three quotes are presented as "Peter Parley's Message to Teachers." (1) "Students wish to participate in their own learning. Begin with the child's present location in time and space, then help the child make connections with the content which you are addressing." (2) "Students are interested in stories and pictures.…

  17. Two Causes of Underachievement--The Scapegoat Phenomenon and the Peter Pan Syndrome. Part II.

    ERIC Educational Resources Information Center

    Grau, Phyllis Nelson

    1986-01-01

    Two profiles of underachievement are described: the Peter Pan Syndrome, characterized by irresponsibility, anxiety, loneliness, sex role conflict, and narcissism, and the scapegoating phenomenon, in which children acquire negative self-images from victimization experiences. Prognoses and recommendations for each are offered. (Author/CL)

  18. Local and Global in the Formation of a Learning Theorist: Peter Jarvis and Adult Education

    ERIC Educational Resources Information Center

    Holford, John

    2017-01-01

    Peter Jarvis is a towering figure in the study of adult and lifelong education and a leading and original theorist of learning. This paper sets out his intellectual and professional biography, maps the main contours of his work and introduces fourteen papers by leading scholars devoted to his work. Five broad phases in Jarvis' life are identified:…

  19. In Search of Excellence--A Talk with Tom Peters about the Principalship. A "Bulletin" Special.

    ERIC Educational Resources Information Center

    Koerner, Tom

    1988-01-01

    Asked about principals' leadership role, Peters claims we've gone wrong by emphasizing the superstructure over the unit commander and by taking "leading" and "managing" distinctions too seriously. Vision and people skills are all-important. Unfortunately, schools have drawn from the worst of private-sector management and…

  20. Behavioral Determinants of Drug Action: The Contributions of Peter B. Dews

    ERIC Educational Resources Information Center

    Barrett, James E.

    2006-01-01

    Peter B. Dews played a significant role in shaping the distinctive characteristics and defining the underlying principles of the discipline of behavioral pharmacology. His early and sophisticated use of schedules of reinforcement in the 1950s, incorporated from research in the experimental analysis of behavior and integrated into the discipline of…

  1. A Critique of Peter Jarvis's Conceptualisation of the Lifelong Learner in the Contemporary Cultural Context

    ERIC Educational Resources Information Center

    Bagnall, Richard G.

    2017-01-01

    This paper examines Peter Jarvis's conceptualisation of lifelong learners, who are seen as being the individual products of their learning engagements, constrained by their individual biological potentials. They are presented as seeking existentially authentic resolution to dialectically oppositional disjunctures between their individual…

  2. Remaking Critical Pedagogy: Peter McLaren's Contribution to a Collective Work

    ERIC Educational Resources Information Center

    Martin, Gregory

    2006-01-01

    This article explores the collective works of Peter McLaren and his contribution to critical pedagogy within the field of education and beyond the academy. To understand how McLaren's work took a radical turn in the 1990s, the article traces the historical development of his praxis. In particular, McLaren's engagement with the postmodern Left and…

  3. Teaching Behavior Analysis and Psychology in Social Context: An Interview with Peter Harzem.

    ERIC Educational Resources Information Center

    Buskist, William

    2000-01-01

    Presents an interview with Peter Harzem, the Hudson Professor of Psychology at Auburn University (Alabama). Addresses such issues as teaching students about behavior analysis, the differences between classical and operant conditioning, reinforcement and behaviorism, and how one can become a better teacher. (CMK)

  4. Reason and Virtues: The Paradox of R. S. Peters on Moral Education

    ERIC Educational Resources Information Center

    Haydon, Graham

    2009-01-01

    This article examines the work of R. S. Peters on moral development and moral education, as represented in his papers collected under that name, pointing out that these writings have been relatively neglected. It approaches these writings through the lens of the "familiar story" that philosophical work on this topic switched during, roughly, the…

  5. Instruction in the Making: Peter Ramus and the Beginnings of Modern Schooling.

    ERIC Educational Resources Information Center

    Hamilton, David

    This paper examines educational practice between 1450-1650, highlighting 16th century educationist, Peter Ramus, whose work is remembered in the "History of Western Philosophy" as fostering a "pedagogic marvel." Ramus' work has received scant attention from English-speaking educationists, and his niche within the educational…

  6. How Relevant Is R. S. Peters' Conception of Education to Science Education?

    ERIC Educational Resources Information Center

    Hadzigeorgiou, Yannis; Stamatis, Panagiotis

    2017-01-01

    This paper discusses R. S. Peters' concept of education, particularly his notion of cognitive perspective and its relevance to school science education. In light of the problems inherent in any attempt to define the notion of scientific literacy, it is argued that the development of cognitive perspective can be considered an important, if not the…

  7. Globalisation in Africa: Reflecting on Peter Jarvis's Superstructure and Substructure Model

    ERIC Educational Resources Information Center

    Preece, Julia

    2017-01-01

    This paper reflects on Peter Jarvis' book "Globalisation, lifelong learning and the learning society," volume 2--in which he describes human learning within a global context and factors contributing to globalisation. He describes the relationship of power between countries manifested as the superstructure and sub structure. The paper…

  8. The Place of Philosophy in the Training of Teachers: Peters Revisited

    ERIC Educational Resources Information Center

    Clark, John A.

    2013-01-01

    In 1964, Richard Peters examined the place of philosophy in the training of teachers. He considered three things: Why should philosophy of education be included in the training of teachers; What portion of philosophy of education should be included; How should philosophy be taught to those training to be teachers. This article explores the context…

  9. The learning organization: adapted from The fifth discipline by Peter Senge.

    PubMed

    Cathon, D E

    2000-02-01

    In his book The Fifth Discipline, Peter Senge presents a system of thinking and acting that can be the basis for reducing the "learning disabilities" in an organization. In an article, written from the perspective of a multidepartmental health care manager, the author reviews Senge's disciplines and how they relate to running a department today.

  10. Perspective on Open-Access Publishing: An Interview with Peter Suber

    ERIC Educational Resources Information Center

    Cornwell, Reid; Suber, Peter

    2008-01-01

    In this edition of Perspectives, Reid Cornwell discusses open-access publishing with Peter Suber, senior researcher at the Scholarly Publishing and Academic Resources Coalition, senior research professor of philosophy at Earlham College, and currently visiting fellow at Yale Law School. Open access means that scholarly work is freely and openly…

  11. The Place of Philosophy in the Training of Teachers: Peters Revisited

    ERIC Educational Resources Information Center

    Clark, John A.

    2013-01-01

    In 1964, Richard Peters examined the place of philosophy in the training of teachers. He considered three things: Why should philosophy of education be included in the training of teachers; What portion of philosophy of education should be included; How should philosophy be taught to those training to be teachers. This article explores the context…

  12. Perspective on Open-Access Publishing: An Interview with Peter Suber

    ERIC Educational Resources Information Center

    Cornwell, Reid; Suber, Peter

    2008-01-01

    In this edition of Perspectives, Reid Cornwell discusses open-access publishing with Peter Suber, senior researcher at the Scholarly Publishing and Academic Resources Coalition, senior research professor of philosophy at Earlham College, and currently visiting fellow at Yale Law School. Open access means that scholarly work is freely and openly…

  13. "Staying on Task": What Constitutes Classwork in Peter Medway's "Finding a Language"?

    ERIC Educational Resources Information Center

    Pangilinan, J. P.

    2015-01-01

    In "Finding a Language", Peter Medway addresses questions of central importance to English teaching--questions of curriculum and of pedagogy. How he addresses these questions provides a sharp contrast to the current orthodoxies of a rigidly prescriptive national curriculum and a closely monitored regime of objective-led, skills-based…

  14. Von Karman re-visited

    NASA Astrophysics Data System (ADS)

    McEligot, Donald M.; Nolan, Kevin P.; Walsh, Edmond J.

    2012-11-01

    A number of authors have presented extended versions of the integral momentum equation, allowing for perturbations or fluctuations in the boundary layer. ``Conventional wisdom'' is that these added terms can be neglected and one can apply the von Karman version directly. For two-dimensional turbulent boundary layers at high Reynolds numbers, experience shows this assumption to be reasonable. However, recent examination of entropy generation in bypass transition with zero pressure gradient shows a term for turbulence energy convection can be important in determining the energy dissipation coefficient [Walsh et al., JFE 2011]. The present study employs the direct numerical simulations of Zaki and Durbin [JFM 2006] for bypass transition with streamwise pressure gradients to quantify the additional normal stress term when estimating the skin friction coefficient via a momentum balance. It is found that this term becomes noticeable in the pre-transitional laminar boundary layer and can exceed forty per cent of Cf in the transition region. Thus, it should be included in such calculations. Partly supported by U. S. DoE EPSCoR office.

  15. [Biology of von Willebrand factor].

    PubMed

    Girma, Jean-Pierre

    2006-01-01

    Von Willebrand factor (VWF) is a multimeric glycoprotein synthesized by megakaryocytes and endothelial cells. It is stored in platelets and endothelial cells and secreted towards subendothelium and plasma. VWF multimers consist of linear arrangements of identical subunits with a molecular weight of 270 kDa. The longest multimers reach more than 20 x 10(6) Da in storage granules. In the circulation, the multimer size is limited by the specific protease ADAMTS13. In primary hemostasis, VWF plays a key role as a molecular bridge in adhesion between platelets and subendothelium and between platelets during their aggregation. These functions, which involve the interaction with platelet glycoprotein lb, are mainly enhanced by VWF immobilization onto hydrophobic surfaces (collagen, cell membrane) and by high shear rates found in microcirculation and stenosed arteries. In these functions, the higher molecular weight forms are the most efficient. Under such hemodynamic conditions, proteolytic activity of ADAMTS13 is also optimal and limits the multimer size to about 15 x 10(6) Da as soon as their secretion. Thus ADAMTS13 appears as a key physiologic regulator of the VWF platelet functions. In the microcirculation, the lack of ADAMTS13 activity can result in the formation of VWF-rich platelet aggregates responsible for thrombotic thrombocytopenic purpura.

  16. An MRI Von Economo - Koskinas atlas.

    PubMed

    Scholtens, Lianne H; de Reus, Marcel A; de Lange, Siemon C; Schmidt, Ruben; van den Heuvel, Martijn P

    2016-12-28

    The cerebral cortex displays substantial variation in cellular architecture, a regional patterning that has been of great interest to anatomists for centuries. In 1925, Constantin von Economo and George Koskinas published a detailed atlas of the human cerebral cortex, describing a cytoarchitectonic division of the cortical mantle into over 40 distinct areas. Von Economo and Koskinas accompanied their seminal work with large photomicrographic plates of their histological slides, together with tables containing for each described region detailed morphological layer-specific information on neuronal count, neuron size and thickness of the cortical mantle. Here, we aimed to make this legacy data accessible and relatable to in vivo neuroimaging data by constructing a digital Von Economo - Koskinas atlas compatible with the widely used FreeSurfer software suite. In this technical note we describe the procedures used for manual segmentation of the Von Economo - Koskinas atlas onto individual T1 scans and the subsequent construction of the digital atlas. We provide the files needed to run the atlas on new FreeSurfer data, together with some simple code of how to apply the atlas to T1 scans within the FreeSurfer software suite. The digital Von Economo - Koskinas atlas is easily applicable to modern day anatomical MRI data and is made publicly available online.

  17. Sulfation of von Willebrand factor

    SciTech Connect

    Carew, J.A.; Browning, P.J.; Lynch, D.C. )

    1990-12-15

    von Willebrand factor (vWF) is a multimeric adhesive glycoprotein essential for normal hemostasis. We have discovered that cultured human umbilical vein endothelial cells incorporate inorganic sulfate into vWF. Following immunoisolation and analysis by polyacrylamide or agarose gel electrophoresis, metabolically labeled vWF was found to have incorporated (35S)-sulfate into all secreted multimer species. The time course of incorporation shows that sulfation occurs late in the biosynthesis of vWF, near the point at which multimerization occurs. Quantitative analysis suggests the presence, on average, of one molecule of sulfate per mature vWF subunit. Virtually all the detectable sulfate is released from the mature vWF subunit by treatment with endoglycosidases that remove asparagine-linked carbohydrates. Sulfated carbohydrate was localized first to the N-terminal half of the mature subunit (amino acids 1 through 1,365) by partial proteolytic digestion with protease V8; and subsequently to a smaller fragment within this region (amino acids 273 through 511) by sequential digestions with protease V8 and trypsin. Thus, the carbohydrate at asparagine 384 and/or 468 appears to be the site of sulfate modification. Sodium chlorate, an inhibitor of adenosine triphosphate-sulfurylase, blocks sulfation of vWF without affecting either the ability of vWF to assemble into high molecular weight multimers or the ability of vWF multimers to enter Weible-Palade bodies. The stability of vWF multimers in the presence of an endothelial cell monolayer also was unaffected by the sulfation state. Additionally, we have found that the cleaved propeptide of vWF is sulfated on asparagine-linked carbohydrate.

  18. Dr. Wernher Von Braun with Dr. Christian Barnard.

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. Christian Barnard Tours Marshall Space Flight Center. Shown in Dr. Von Braun's office are (left to right): Dr. Ernst Sthulinger, a representative from General Electric, Dr. Wernher Von Braun, Dr. Christian Barnard, and Dr. Eberhard Rees.

  19. Dr. Wernher Von Braun with Dr. Christian Barnard.

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. Christian Barnard Tours Marshall Space Flight Center. Shown in Dr. Von Braun's office are (left to right): Dr. Ernst Sthulinger, a representative from General Electric, Dr. Wernher Von Braun, Dr. Christian Barnard, and Dr. Eberhard Rees.

  20. State of the art: von Willebrand disease.

    PubMed

    James, A H; Eikenboom, J; Federici, A B

    2016-07-01

    The State of the Art in von Willebrand disease (VWD) has been impacted not only by discoveries in the field of haemostasis, but also by changes in practice in other fields. The development of bleeding assessment tools has led to the clarification of bleeding symptoms and phenotype in VWD. New discoveries in the biology and genetics of von Willebrand factor (VWF) are challenging our existing diagnostics and classification(s). An improved understanding of reproductive physiology and the pathology of VWD along with changing obstetric, gynaecologic and haemostatic therapies necessitate an evolving response to the care of women with VWD. The survival of patients with autoimmune disease, malignancies and congenital heart disease along with increasing use of circulatory support devices and extracorporeal membrane oxygenation is increasing the prevalence of acquired von Willebrand syndrome. In each of these challenges, there are opportunities to improve the care of our patients with VWD.

  1. Treatment of the acquired von Willebrand syndrome.

    PubMed

    Budde, Ulrich; Scheppenheim, Sonja; Dittmer, Rita

    2015-12-01

    Acquired von Willebrand syndrome (aVWS) accounts for 22% of patients with abnormal von Willebrand factor. Most patients with known pathophysiological mechanisms suffer from cardiovascular, myeloproliferative and lymphoproliferative disorders. Less frequent associations are of autoimmune origin, due to hyperfibrinolysis, adsorption to tumor cells, reduced synthesis and prolonged circulation. The mechanisms leading to aVWS is hitherto not known in patients with liver and kidney diseases, drug use, glycogen storage disease, virus infections and at least 18 other disease entities. Diagnosis is complicated by the battery of tests needed, and their inherent rather low sensitivity and specificity for aVWS. Thus, even in acute bleeding situations it may take days until a firm diagnosis is settled and specific therapies can be initiated. The main aim is to shed more light onto this, compared with inherited von Willebrand disease, rare disease which affects at least 2-3% of the older population.

  2. Liouville-von Neumann molecular dynamics.

    PubMed

    Jakowski, Jacek; Morokuma, Keiji

    2009-06-14

    We present a novel first principles molecular dynamics scheme, called Liouville-von Neumann molecular dynamics, based on Liouville-von Neumann equation for density matrices propagation and Magnus expansion of the time-evolution operator. The scheme combines formally accurate quantum propagation of electrons represented via density matrices and a classical propagation of nuclei. The method requires a few iterations per each time step where the Fock operator is formed and von Neumann equation is integrated. The algorithm (a) is free of constraint and fictitious parameters, (b) avoids diagonalization of the Fock operator, and (c) can be used in the case of fractional occupation as in metallic systems. The algorithm is very stable, and has a very good conservation of energy even in cases when a good quality conventional Born-Oppenheimer molecular dynamics trajectories is difficult to obtain. Test simulations include initial phase of fullerene formation from gaseous C(2) and retinal system.

  3. Liouville-von Neumann molecular dynamics

    NASA Astrophysics Data System (ADS)

    Jakowski, Jacek; Morokuma, Keiji

    2009-06-01

    We present a novel first principles molecular dynamics scheme, called Liouville-von Neumann molecular dynamics, based on Liouville-von Neumann equation for density matrices propagation and Magnus expansion of the time-evolution operator. The scheme combines formally accurate quantum propagation of electrons represented via density matrices and a classical propagation of nuclei. The method requires a few iterations per each time step where the Fock operator is formed and von Neumann equation is integrated. The algorithm (a) is free of constraint and fictitious parameters, (b) avoids diagonalization of the Fock operator, and (c) can be used in the case of fractional occupation as in metallic systems. The algorithm is very stable, and has a very good conservation of energy even in cases when a good quality conventional Born-Oppenheimer molecular dynamics trajectories is difficult to obtain. Test simulations include initial phase of fullerene formation from gaseous C2 and retinal system.

  4. Mittelwert- und Arbeitstaktsynchrone Simulation von Dieselmotoren

    NASA Astrophysics Data System (ADS)

    Zahn, Sebastian

    Getrieben durch die immer restriktiveren Anforderungen an das Emissions- und Verbrauchsverhalten moderner Verbrennungsmotoren steigt die Komplexität von Motormanagementsystemen mit jeder Modellgeneration an. Damit geht nicht nur eine Zunahme des Softwareumfangs von Steuergeräten sondern zugleich ein deutlicher Anstieg des Applikations-, Vermessungs- und Testaufwandes einher. Zur Effizienzsteigerung des Software- und Funktionsentwicklungsprozesses haben sich daher in der Automobilindustrie sowie in Forschungsinstituten verschiedene modell- und simulationsbasierte Methoden wie die Model-in-the-Loop (MiL) Simulation, die Software-in-the-Loop (SiL) Simulation, das Rapid Control Prototyping (RCP) sowie die Hardware-in-the-Loop (HiL) Simulation etabliert.

  5. [Research advance in von Willebrand factor].

    PubMed

    Li, Xue-Mei; Jiang, Miao; Zhao, Yi-Ming

    2013-06-01

    von Willebrand factor (vWF) is a multimeric glycoprotein exclusively synthesized in endothelial cells and megakaryocytes. It plays important roles in the primary and secondary haemostasis. Deficiency or dysfunction of vWF may cause von Willebrand disease (vWD), and overexpression of vWF may cause thrombosis. Making an intensive study on vWF will help us to understand the pathophysiology, diagnosis and treatment of vWF-related diseases, such as vWD, TTP, venous thrombosis, stroke, and so on. In this article, the regulation of vWF activity and its relation with diseases mentioned above are reviewed.

  6. Laboratory diagnosis of von Willebrand disease.

    PubMed

    Roberts, J C; Flood, V H

    2015-05-01

    Von Willebrand disease (VWD) is considered the most common inherited bleeding disorder and may also be the most difficult to diagnose. Clinical symptoms of VWD include predominantly mild mucosal bleeding; surgical bleeding may occur with specific challenges and joint bleeding can occur in the most severe forms. A family history either of diagnosed VWD or of bleeding symptoms is typically present. Laboratory diagnosis requires a series of assays of von Willebrand factor (VWF) quantity and function, and factor VIII activity, with no single straightforward diagnostic test available to either confirm or exclude the diagnosis. Newer assays of VWF function are becoming more available and useful in determining the laboratory diagnosis of VWD.

  7. Level-Set-Segmentierung von Rattenhirn MRTs

    NASA Astrophysics Data System (ADS)

    Eiben, Björn; Kunz, Dietmar; Pietrzyk, Uwe; Palm, Christoph

    In dieser Arbeit wird die Segmentierung von Gehirngewebe aus Kopfaufnahmen von Ratten mittels Level-Set-Methoden vorgeschlagen. Dazu wird ein zweidimensionaler, kontrastbasierter Ansatz zu einem dreidimensionalen, lokal an die Bildintensität adaptierten Segmentierer erweitert. Es wird gezeigt, dass mit diesem echten 3D-Ansatz die lokalen Bildstrukturen besser berücksichtigt werden können. Insbesondere Magnet-Resonanz-Tomographien (MRTs) mit globalen Helligkeitsgradienten, beispielsweise bedingt durch Oberfiächenspulen, können auf diese Weise zuverlässiger und ohne weitere Vorverarbeitungsschritte segmentiert werden. Die Leistungsfähigkeit des Algorithmus wird experimentell an Hand dreier Rattenhirn-MRTs demonstriert.

  8. Ökologische Aspekte von Thin Clients

    NASA Astrophysics Data System (ADS)

    von Knermann, Christian

    Hersteller von IT-Technologie haben angesichts der Debatte um Klimaschutz und Nachhaltigkeit erkannt, dass für Endkunden, ob privat oder gewerblich, auch ökologische Gesichtspunkte beim Kauf von PC, Laptop oder Netzwerkgeräten eine immer größere Rolle spielen und Energie- oder Ökoeffizienz der Geräte kaufentscheidend wirken können. Betrachtet und bewertet wurden bislang aber hauptsächlich isolierte Einzelaspekte, wie der Energieverbrauch in der Nutzungsphase oder der Einsatz toxikologisch unbedenklicher Stoffe. Was fehlt, ist eine ganzheitliche Ausrichtung auf Nachhaltigkeit über die Lebensphasen Produktion, Nutzung sowie Recyling/Entsorgung.

  9. Biosynthesis, processing and secretion of von Willebrand factor: biological implications.

    PubMed

    de Wit, T R; van Mourik, J A

    2001-06-01

    von Willebrand factor is a multimeric plasma glycoprotein that is required for normal haemostasis. von Willebrand factor is synthesized by endothelial cells and megakaryocytes, and originates from its precursor pro-von Willebrand factor. The endoproteolytic processing of pro-von Willebrand factor results in mature von Willebrand factor and von Willebrand factor propeptide (also known as von Willebrand Ag II). In endothelial cells, the propeptide controls the polymerization and subsequent targeting of von Willebrand factor to the storage vesicles, the so-called Weibel-Palade bodies. Upon stimulation of the endothelial cells, the Weibel-Palade bodies are translocated to the plasma membrane of the cell, and mature von Willebrand factor and its propeptide are co-secreted. After release, these polypeptides have divergent fates and serve different biological functions. Mature von Willebrand factor both controls platelet adhesion and aggregation at sites of vascular injury and acts as a chaperone protein for coagulation factor VIII. The von Willebrand factor propeptide may serve a role in modulating inflammatory processes. This still growing body of information indicates that the biological function of the von Willebrand factor gene product is more diverse than was previously thought.

  10. [Questions on the first operation with ethyl ether as anaesthetic by Dr. Peter Parker].

    PubMed

    Chen, Q

    2017-01-28

    Ethyl ether was the first accepted effective general anaesthetic. It was introduced into China by an America missionary, Dr. Peter Parker. This was one of the historical events of medical communication between China and the West. In the records of the first operation with ether, however, Dr. Parker unusually omitted the patient's medical record number and the date of the operation, while those of other operations with ether anesthetics were all available. This was very unusual for a doctor like Peter Parker who always recorded every important case in detail in the hospital reports. It seems that he deliberately rather than carelessly omitted the information for some reasons. Based on the analysis of Parker's reports, a conclusion is made that the anesthetic effect of the case was actually ineffective. Furthermore, possible answers to this are outlined and question by discussion based on the situation that Parker faced in the late Qing era.

  11. Peter of Spain's handling of authorities in his commentary on the Isagoge of Johannitius.

    PubMed

    De Asua, M

    2000-01-01

    The dicta from medical and philosophical authorities appearing in commentaries on the Isagoge of Johannitius may be classified according to the different roles they play in the exposition of the text. This paper establishes that the opinions of the philosophical and medico-philosophical authorities were used more frequently as the consituent elements of inferences, whereas the dicta of purely medical authorities were quoted straightforwardly as sententiae. An exception to this is Peter of Spain who does not follow any hierarchical organization of authorities; instead, he freely quotes Aristotle in opposition to the physicians as well as in support of them. These observations are explained with specific reference to Peter's ideas on the relationsip between medicine and philosophy.

  12. An Interview with Peter McLaren: Comments on the State of the World-2005

    ERIC Educational Resources Information Center

    Shaughnessy, Michael F.

    2006-01-01

    Some of the wide range of thoughtful topics discussed in this interview with Peter McLaren include: (1) The top five points that McLaren tried to make in his book, "Capitalists and Conquerors: A Critical Pedagogy Against Empire"; (2) McLaren's thoughts on what he thinks the George Bush legend will be; (3) What led McLaren to ask,…

  13. An Interview with Peter McLaren: Comments on the State of the World-2005

    ERIC Educational Resources Information Center

    Shaughnessy, Michael F.

    2006-01-01

    Some of the wide range of thoughtful topics discussed in this interview with Peter McLaren include: (1) The top five points that McLaren tried to make in his book, "Capitalists and Conquerors: A Critical Pedagogy Against Empire"; (2) McLaren's thoughts on what he thinks the George Bush legend will be; (3) What led McLaren to ask,…

  14. A new species of the genus Diplocentrus Peters, 1861 (Scorpiones, Diplocentridae) from Oaxaca, Mexico.

    PubMed

    Santibáñez-López, Carlos Eduardo

    2014-01-01

    A new species of the genus Diplocentrus Peters, 1861 is described, based on several specimens collected in the Mexican state of Oaxaca. It is characterized by a high telotarsal spiniform setae count (4-5/5:5/6:6/6:6/6-7), and the pectinal tooth counts of 12-15, mode = 13 (male) or 11-13, mode = 12 (female). With the description of this species, the diversity of the genus is increased to 51 species in Mexico.

  15. A new species of the genus Diplocentrus Peters, 1861 (Scorpiones, Diplocentridae) from Oaxaca, Mexico

    PubMed Central

    Santibáñez-López, Carlos Eduardo

    2014-01-01

    Abstract A new species of the genus Diplocentrus Peters, 1861 is described, based on several specimens collected in the Mexican state of Oaxaca. It is characterized by a high telotarsal spiniform setae count (4-5/5:5/6:6/6:6/6-7), and the pectinal tooth counts of 12–15, mode = 13 (male) or 11–13, mode = 12 (female). With the description of this species, the diversity of the genus is increased to 51 species in Mexico. PMID:24899864

  16. Peters Anomaly in Twins: A Case Report of a Rare Incident with Novel Comorbidities.

    PubMed

    Almarzouki, Hashem S; Tayyib, Alaa A; Khayat, Hassan A; Alsulami, Raed E; Alzahrani, Saeed M; Alkahtani, Abdulaziz S; Alghifees, Loai S

    2016-01-01

    Peters anomaly is a rare developmental malformation involving the anterior segment of the eye, which culminates in amblyopia or congenital blindness. Multiple ocular and/or systemic malformations have been observed with this anomaly, and novel comorbidities continue to be reported. The probands were monozygotic twin boys (twin I and twin II) born to consanguineous parents at 36 weeks of gestation. Coarse facial features and deep-seated eyes were noted at birth. At 6 months, ophthalmic examination revealed that both twins were unable to blink in response to light, or to fixate and follow a moving object. Both twins had prominent horizontal nystagmus. Slit-lamp examination demonstrated varying degrees of central leukoma (corneal opacity) associated with iridocorneal adhesion, which is characteristic of type I Peters anomaly. No cataractous changes were observed. Normal intraocular pressure and disorganized retina were observed. Pupillary abnormalities included bilaterally underdeveloped pupils and bilateral absence of pupils was noted. Ocular MRI showed bilateral microphthalmia and optic nerve hypoplasia, with a small optic chiasm in both twins. At this age, the diagnosis of Peters anomaly was made. At 16 months of age, both twins developed deep venous thrombosis and purpuric skin lesions. Investigations revealed a hereditary thrombophilia secondary to a homozygous mutation causing protein C deficiency, which is a rare thrombotic condition. Ocular ultrasonography revealed bilateral vitreous hemorrhaging linked to altered coagulation. One twin developed bilateral inguinal hernia and cryptorchidism. The novel concordance of Peters anomaly in these monozygotic twins sharing a mutation in PROC gene provides further evidence that this anomaly has a genetic basis. Hypoplasia of the optic nerves and optic chiasm, along with severe protein C deficiency and bilateral absence of the pupils, are associated comorbidities that have not previously been reported with this anomaly.

  17. Regional diagenetic patterns in the St. Peter Sandstone; implications for brine migration in the Illinois Basin

    USGS Publications Warehouse

    Pitman, Janet K.; Goldhaber, Martin B.; Spoetl, Christoph

    1997-01-01

    Diagenetic minerals and alteration patterns in the Ordovician St. Peter Sandstone, Illinois Basin, record varied hydrologic and chemical conditions during the basin?s long and complex geologic history. Major diagenetic events modifying the St. Peter Sandstone include (1) mechanical compaction, (2) early K-feldspar overgrowth and dolospar precipitation, (3) burial quartz, dolospar, anhydrite, and calcite cementation, and (4) carbonate-cement and K-feldspar grain dissolution. Radiometric age dates of authigenic K-feldspar and illite in combination with the reconstructed burial history of the St. Peter reveal that early-diagenetic K-feldspar and dolospar precipitated at shallow to moderate depths in the Devonian, whereas late-diagenetic quartz, dolospar, anhydrite, and calcite formed during deep burial in the Late Pennsylvanian to Early Permian. Stable-isotope geochemistry and fluid-inclusion paleothermometry suggest that burial cements precipitated from saline fluids over a wide temperature range. In the southern part of the basin, burial cements preserve a record of diagenetic effects that were in part controlled by fractures and hydrothermal-fluid circulation. Baroque dolospar cementation is the most significant of these effects.

  18. Impaired ADAMTS9 secretion: A potential mechanism for eye defects in Peters Plus Syndrome

    PubMed Central

    Dubail, Johanne; Vasudevan, Deepika; Wang, Lauren W.; Earp, Sarah E.; Jenkins, Michael W.; Haltiwanger, Robert S.; Apte, Suneel S.

    2016-01-01

    Peters Plus syndrome (PPS), a congenital disorder of glycosylation, results from recessive mutations affecting the glucosyltransferase B3GLCT, leading to congenital corneal opacity and diverse extra-ocular manifestations. Together with the fucosyltransferase POFUT2, B3GLCT adds Glucoseβ1-3Fucose disaccharide to a consensus sequence in thrombospondin type 1 repeats (TSRs) of several proteins. Which of these target proteins is functionally compromised in PPS is unknown. We report here that haploinsufficiency of murine Adamts9, encoding a secreted metalloproteinase with 15 TSRs, leads to congenital corneal opacity and Peters anomaly (persistent lens-cornea adhesion), which is a hallmark of PPS. Mass spectrometry of recombinant ADAMTS9 showed that 9 of 12 TSRs with the O-fucosylation consensus sequence carried the Glucoseβ1-3Fucose disaccharide and B3GLCT knockdown reduced ADAMTS9 secretion in HEK293F cells. Together, the genetic and biochemical findings imply a dosage-dependent role for ADAMTS9 in ocular morphogenesis. Reduced secretion of ADAMTS9 in the absence of B3GLCT is proposed as a mechanism of Peters anomaly in PPS. The functional link between ADAMTS9 and B3GLCT established here also provides credence to their recently reported association with age-related macular degeneration. PMID:27687499

  19. Interview with Tom Peters. Father of post-modern corporation speaks out. Interview by Richard D. Brennan, Jr.

    PubMed

    Peters, Tom

    2005-06-01

    Tom Peters has been selected as the opening Keynote speaker at the National Association for Home Care and Hospice's Annual Meeting in Seattle, Washington on October 23-26, 2005. Peters has been described by the Los Angeles Times as the "father of the post-modern corporation." The New Yorker said, "In no small part, what American corporations have become is what Peters has encouraged them to be." Fortune called Tom Peters the top guru of management, and compares him to Ralph Waldo Emerson, Henry David Thoreau, Walt Whitman, and H.L. Mencken. The Economist tagged him the Uber-guru; and BusinessWeek's take on his "unconventional views" led them to label him "business's best friend and worst nightmare."

  20. On the Peter Principle: An agent based investigation into the consequential effects of social networks and behavioural factors

    NASA Astrophysics Data System (ADS)

    Fetta, A. G.; Harper, P. R.; Knight, V. A.; Vieira, I. T.; Williams, J. E.

    2012-05-01

    The Peter Principle is a theory that provides a paradoxical explanation for job incompetence in a hierarchical organisation. It argues that should staff be competent at a given level, their competence may not be implicit at higher levels due to the differences in the skill set required. Furthering the work of a recent investigation into the Peter Principle utilising agent based simulation, this paper explores external factors upon varying promotion strategies to assess efficiency. Through additional elements of social networks and organisational thought, a more representative view of workplace interaction is presented. Results of the simulation found that although the Peter Principle affects efficiency, it may not be to the levels previously suggested. Furthermore promotion on merit provided the most favourable maximum and minimum efficiency margins, given the absence of clear evidence pertaining to the existence of the Peter Principle.

  1. Dr. von Braun Visits Huntsville Boys Club

    NASA Technical Reports Server (NTRS)

    1961-01-01

    Dr. von Braun, Director of Marshall Space Flight Center (MSFC) and chairman of this year's United Givers Fund (UGF) drive at MSFC, takes time out from the problems of sending a man to the Moon to talk baseball with 11-year-old Randy Smith at the Huntsville Boys Club.

  2. Dr. von Braun and His Mercedes

    NASA Technical Reports Server (NTRS)

    1959-01-01

    In this picture, Dr. Wernher von Braun, who was serving as Director of the Army Ballistic Missile Agency's (ABMA) Development Operations Division, is shown posed with his Mercedes 220SE automobile in front of Redstone Building 4488, which houses the ABMA.

  3. [The Costantin Von Economo's lethargic encefalitis

    PubMed

    Pistacchio, E.

    1998-01-01

    Starting from the Constantin Von Economo's description of a "new" disease, the lethargic encephalitis, the author delineates the history of an infectious sleeping sickness that caused epidemics in Europe from 1917 to 1928 and led to create, in Italy, the "Institutes for Encephalitis".

  4. Dr. Wernher Von Braun presents a certificate

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. Wernher Von Braun (left), director of the Marshall Space Flight Center, presents a humorous certificate to Major General Charles W. Eifler, commanding general of Redstone Arsenal, at the close of a farewell luncheon for the general prior to General Eifler moving to a new European duty station.

  5. Alexander von Humboldt: a revolutionary explorer.

    PubMed

    Fara, Patricia

    2008-03-01

    After he returned from his five-year expedition to the New World, Alexander von Humboldt promoted himself as a Romantic explorer. Although this image pervades British perceptions, political movements have fashioned different heroic versions of Humboldt in Germany and South America.

  6. Dr. Wernher Von Braun presents a certificate

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. Wernher Von Braun (left), director of the Marshall Space Flight Center, presents a humorous certificate to Major General Charles W. Eifler, commanding general of Redstone Arsenal, at the close of a farewell luncheon for the general prior to General Eifler moving to a new European duty station.

  7. Dr. von Braun Discusses 'Bottle Suit' Concept

    NASA Technical Reports Server (NTRS)

    1954-01-01

    Dr. Wernher von Braun (center), then Chief of the Guided Missile Development Division at Redstone Arsenal, Alabama, discusses a 'bottle suit' model with Dr. Heinz Haber (left), an expert on aviation medicine, and Willey Ley, a science writer on rocketry and space exploration. The three men were at the Disney studios appearing in the motion picture, entitled 'Man in Space.'

  8. Dr. von Braun Discusses 'Bottle Suit' Concept

    NASA Technical Reports Server (NTRS)

    1954-01-01

    Dr. Wernher von Braun (center), then Chief of the Guided Missile Development Division at Redstone Arsenal, Alabama, discusses a 'bottle suit' model with Dr. Heinz Haber (left), an expert on aviation medicine, and Willey Ley, a science writer on rocketry and space exploration. The three men were at the Disney studios appearing in the motion picture, entitled 'Man in Space.'

  9. A note on derivations of Murray–von Neumann algebras

    PubMed Central

    Kadison, Richard V.; Liu, Zhe

    2014-01-01

    A Murray–von Neumann algebra is the algebra of operators affiliated with a finite von Neumann algebra. In this article, we first present a brief introduction to the theory of derivations of operator algebras from both the physical and mathematical points of view. We then describe our recent work on derivations of Murray–von Neumann algebras. We show that the “extended derivations” of a Murray–von Neumann algebra, those that map the associated finite von Neumann algebra into itself, are inner. In particular, we prove that the only derivation that maps a Murray–von Neumann algebra associated with a factor of type II1 into that factor is 0. Those results are extensions of Singer’s seminal result answering a question of Kaplansky, as applied to von Neumann algebras: The algebra may be noncommutative and may even contain unbounded elements. PMID:24469831

  10. [Von Willebrand disease. Molecular biology and diagnosis].

    PubMed

    Hernández-Zamora, Edgar; Zavala-Hernández, Cesar; Quintana-González, Sandra; Reyes-Maldonado, Elba

    2015-01-01

    Von Willebrand disease is the most common inherited disorder of the coagulation proteins in humans. There are three types: 1, 2A, 2B, 2N, 2M and 3. It is associated with mutations on chromosome 12 in the region p13.2, encoding the von Willebrand factor (VWF), which is synthesized in endothelial cells and megakaryocytes. The VWF gene has been characterised using molecular biology techniques, which have acquired an important role in diagnosis von Willebrand disease, as well as in the investigation of alterations in other genes, which may be involved in regulating the synthesis, processing, and secretion of VWF. However, there are still no strategies to integrate the molecular biology diagnostic tests available. Analysis of VWF multimers is a methodology that meets the characteristics for diagnosis, but it is not easy to standardise. Considering that even in tertiary centres in our country, von Willebrand patients do not have a definitive diagnosis, it is necessary to implement these methodologies to study and improve diagnosis. Von Willebrand disease is highly heterogeneous due to the molecular mechanisms that produce the various clinical and laboratory phenotypes. In Mexico there are few studies related to this disease; therefore it is essential to conduct a comprehensive study including clinical, basic, and special testing laboratory tests, in order to establish a correct diagnosis, develop new therapeutic approaches, and offer the appropriate medical care and genetic counselling. Copyright © 2015 Academia Mexicana de Cirugía A.C. Published by Masson Doyma México S.A. All rights reserved.

  11. A double commutant theorem for Murray-von Neumann algebras.

    PubMed

    Liu, Zhe

    2012-05-15

    Murray-von Neumann algebras are algebras of operators affiliated with finite von Neumann algebras. In this article, we study commutativity and affiliation of self-adjoint operators (possibly unbounded). We show that a maximal abelian self-adjoint subalgebra A of the Murray-von Neumann algebra A(f)(R) associated with a finite von Neumann algebra R is the Murray-von Neumann algebra A(f)(A(0)), where A(0) is a maximal abelian self-adjoint subalgebra of R and, in addition, A(0) is A Π R. We also prove that the Murray-von Neumann algebra A(f)(C) with C the center of R is the center of the Murray-von Neumann algebra A(f)(R). Von Neumann's celebrated double commutant theorem characterizes von Neumann algebras R as those for which R'' = R, where R', the commutant of R, is the set of bounded operators on the Hilbert space that commute with all operators in R. At the end of this article, we present a double commutant theorem for Murray-von Neumann algebras.

  12. Remelting and Remobilization in a Magmatic Arc: the St Peter Suite, South Australia

    NASA Astrophysics Data System (ADS)

    Symington, N.; Weinberg, R. F.; Hasalova, P.

    2013-12-01

    Thermo-mechanical models of magmatic arcs suggest that intermittent intrusion of magma batches should lead to remelting and remobilization of earlier intrusive rocks as a result of fluctuations in temperature and water content. However, examples of remelting and remobilization of earlier intrusive rocks, formed during arc-building, are surprisingly rare. We investigate the evolution of magmatic rocks of the Palaeoproterozoic St Peter Suite, in the Gawler Craton, South Australia. This suite records multiple intrusions, magma hybridization, and the remelting and remobilization of these intrusions to form migmatites and newly-formed leucocratic magmas. In this paper we detail first how multiple magma batches interact with one another as liquids and mushes during syn-magmatic deformation phases, and then detail the nature of migmatites resulting from anatexis of these same magmatic rocks and the resulting channel ways that allowed for magma remobilization. LA-ICP/MS U/Pb zircon dating yielded crystallization ages of 1647×12 Ma for an early dioritic-to-granitic suite, and 1604×12 Ma for a later magmatic suite of broadly similar composition. Both these suites underwent anatectic events. Titanite from late-formed leucosomes found within D2 shear zones in the older suite, yielded SHRIMP U/Pb age of 1605×7 Ma, within error of the age of the younger suite. We therefore infer that intrusion, crystallization and remelting/remobilization of this younger suite of rocks occurred within 10-15 M.yr. We propose that the St Peter Suite exposures represent a frozen-in record of a continuous, multi-stage, repetitive process, common to the core of arcs where multiple magma intrusions drive multiple hybridization events and fluctuations in temperature and water-content trigger remelting and remobilization of the more fractionated sectors of earlier intrusive. Thus, the St Peter Suite record many of the key processes expected in arcs, including the prediction that early intrusive arc

  13. From the classical to the generalized von Karman and Marguerre-von Karman equations

    NASA Astrophysics Data System (ADS)

    Ciarlet, Philippe G.; Gratie, Liliana

    2006-06-01

    In this work, we describe and analyze two models that were recently proposed for modeling generalized von Karman plates and generalized Marguerre-von Karman shallow shells.First, we briefly review the "classical" von Karman and Marguerre-von Karman equations, their physical meaning, and their mathematical justification. We then consider the more general situation where only a portion of the lateral face of a nonlinearly elastic plate or shallow shell is subjected to boundary conditions of von Karman type, while the remaining portion is free. Using techniques from formal asymptotic analysis, we obtain in each case a two-dimensional boundary value problem that is analogous to, but is more general than, the classical equations.In particular, it is remarkable that the boundary conditions for the Airy function can still be determined on the entire boundary of the nonlinearly elastic plate or shallow shell solely from the data.Following recent joint works, we then reduce these more general equations to a single "cubic" operator equation, which generalizes an equation introduced by Berger and Fife, and whose sole unknown is the vertical displacement of the shell. We next adapt an elegant compactness method due to Lions for establishing the existence of a solution to this operator equation.

  14. [Type 2N von Willebrand disease (Normandy)].

    PubMed

    Monpoux, F; Brunet, P; Fischer, F; Appert-Flory, A

    2011-01-01

    Willebrand disease is the most common constitutional abnormality of hemostasis. It reflects a qualitative or quantitative abnormality of von Willebrand factor (vWF) responsible for hemorrhagic syndrome, mainly mucosal, of variable expression. Type 2N (Normandy) is a rare form of von Willebrand disease due to a qualitative abnormality of vWF that disrupts its ability to bind to factor VIII. The disease biologically combines APTT prolongation, a lower level of factor VIII, and a normal or subnormal rate of vWF, which may suggest a mild form of hemophilia A. This confusion can lead not only to a misdiagnosis but also to inappropriate treatment. Copyright © 2010 Elsevier Masson SAS. All rights reserved.

  15. Management of the von Roos operator

    NASA Astrophysics Data System (ADS)

    Molinar-Tabares, Martin; Castro-Arce, Lamberto; Figueroa-Navarro, Carlos; Campos-Garcia, Julio

    When an electron is inside a semiconductor medium its effective mass rises from the shielding of the crystalline structure. When we have a semiconductor with a constant concentration the effective mass has a fixed value, and in this case, it can be easy to solve the Schrodinger equation of the particle, but if the concentration varies spatially, the effective mass will no longer constant and the solution can be difficult to find. The general form of the kinetic energy operator for a particle with variable mass is proposed for von Roos, this operator is characterized by some parameters whose values are subjected to a restriction. From a numerical solution of the Schrodinger equation we analyze the energies of an electron with position-dependent effective mass working with some values of the parameter of the von Roos operator. We acknowledge the support of SNI CONACYT.

  16. [Molecular biology of von Willebrand disease].

    PubMed

    Melo-Nava, Brenda; Peñaloza, Rosenda

    2007-01-01

    Von Willebrand Factor (VWF) is a large multimeric glycoprotein expressed in the megakaryocytes and endothelial cells of all vertebrates. It participates fundamentally in the primary and secondary hemostasis because it induces the adhesion of platelets to vascular subendothelium and promotes aggregation of platelets when blood vessels and capillaries are damaged. In addition, VWF links to factor VIII which avoids its proteolysis. The deficiency or the inadequate synthesis of the VWF causes von Willebrand disease (VWD), which is the most common hereditary bleeding disorder in humans principally from mucous and cutaneous sites. VWD is difficult to detect with accuracy due to interrelation among VWF with different components of hemostasis, although it is performed by different tests of haemostatic system, and the basic mechanisms in VWD are herein emphasized. The diagnosis of VWD is difficult due to the heterogeneous manifestation of the disease, which also complicates its classification. This article focuses on the molecular aspects of the disease and discusses their possible clinical implications.

  17. Vascular Manifestations of von Recklinghausen's Disease

    PubMed Central

    Fye, Kenneth H.; Jacobs, Richard P.; Roe, Robert L.

    1975-01-01

    A casual relationship between von Recklinghausen's disease, or neurofibromatosis, and arteriolar abnormalities has been reported in the European literature. A patient was seen who had biopsy-proved neurofibromatosis and renovascular hypertension and retroperitoneal bleeding. An arteriographic study showed multiple small aneurysms throughout the coeliac axis, the superior mesenteric artery and in several small intrarenal vessels. Renal vein renin levels were elevated particularly in the right renal vein, supporting the diagnosis of renovascular hypertension. Both the aneurysms seen in angiographic studies and the retroperitoneal hemorrhage are probably vascular manifestations of von Recklinghausen's disease. Support for this conclusion is enhanced by the absence of clinical, laboratory or histologic data supporting the only tenable differential diagnosis, periarteritis nodosa. ImagesFigure 1.Figure 2.Figure 3.Figure 4. PMID:803743

  18. Language and Reality. Peter Mittelstaedt's Contributions to the Philosophy of Physics

    NASA Astrophysics Data System (ADS)

    Falkenburg, Brigitte

    2010-10-01

    The article investigates the way in which Peter Mittelstaedt has been contributing to the philosophy of physics for half a century. It is shown that he pursues a path between rationalism and empiricism in the sense of Erhard Scheibe’s philosophy of the physicists. Starting from Kant’s a priori he gives a rational reconstruction of the conceptual revolutions of 20th century physics. The central topic of his philosophy of physics is the quest for semantic self-consistency, which for quantum mechanics is a hard nut to crack.

  19. Peter Andreas Hansen und die astronomische Gemeinschaft - eine erste Auswertung des Hansen-Nachlasses.

    NASA Astrophysics Data System (ADS)

    Schwarz, O.; Strumpf, M.

    The literary assets of Peter Andreas Hansen are deposited in the Staatsarchiv Hamburg, the Forschungs- und Landesbibliothek Gotha and the Thüringer Staatsarchiv Gotha. They were never systematically investigated. The authors present here some results of a first evaluation. It was possible to reconstruct the historical events with regard to the maintenance of the Astronomische Nachrichten and the Altona observatory in 1854. Hansen was a successful teacher for many young astronomers. His way of stimulating the evolution of astronomy followed Zach's tradition.

  20. Communicating Chemistry from Molecules to International Efforts: An Interview with Peter Atkins

    NASA Astrophysics Data System (ADS)

    Cardellini, Liberato

    2008-06-01

    In this interview, Peter Atkins explains the deep motivations that compel him to sit at his desk at 6 AM writing books and textbooks. He discusses the four principal elements that help to make a chemistry textbook successful, including the secret ingredient. He also discusses the importance of problem solving, the interaction of multimedia, and the effect of the Web on textbooks. Finally, Atkins articulates the beliefs that learning chemistry opens our eyes to a deeper enjoyment of the world, that chemistry plumbs a deeper level of reality.

  1. Forest inventory: Peter T. Johnson Wildlife Mitigation Unit, Craig Mountain, Idaho. Final Report.

    SciTech Connect

    Narolski, Steven W.

    1996-12-01

    The primary objective of this report is to determine the quantity and quality of existing forest habitat types on the 59,991-acre Peter T. Johnson Wildlife Mitigation Unit (WMU). Products from this effort include a description of the ecological condition, a map of habitat types, and an inventory of forest resources on the WMU lands. The purpose of this and other resource inventories (plant and wildlife) is to assess the current resources condition of the WMU and to provide necessary information to generate a long-term management for this area.

  2. Herstellung von Chitosan und einige Anwendungen

    NASA Astrophysics Data System (ADS)

    Struszczyk, Marcin Henryk

    2001-05-01

    1. Die Deacetylierung von crabshell - Chitosan führte gleichzeitig zu einem drastischen Abfall der mittleren viscosimetrischen Molmasse ( Mv), insbesondere wenn die Temperatur und die Konzentration an NaOH erhöht werden. Diese Parameter beeinflussten jedoch nicht den Grad der Deacetylierung (DD). Wichtig ist jedoch die Quelle des Ausgangsmaterials: Chitin aus Pandalus borealis ist ein guter Rohstoff für die Herstellung von Chitosan mit niedrigem DD und gleichzeitig hoher mittlerer Mv, während Krill-Chitin (Euphausia superba) ein gutes Ausgangsmaterial zur Herstellung von Chitosan mit hohem DD und niedrigem Mv ist. Chitosan, das aus Insekten (Calliphora erythrocephala), unter milden Bedingungen (Temperatur: 100°C, NaOH-Konzentration: 40 %, Zeit: 1-2h ) hergestellt wurde, hatte die gleichen Eigenschaften hinsichtlich DD und Mv wie das aus Krill hergestellte Chitosan. Der Bedarf an Zeit, Energie und NaOH ist für die Herstellung von Insekten-Chitosan geringer als für crabshell-Chitosan vergleichbare Resultaten für DD und Mv. 2. Chitosan wurde durch den Schimmelpilz Aspergillus fumigatus zu Chitooligomeren fermentiert. Die Ausbeute beträgt 25%. Die Chitooligomere wurden mit Hilfe von HPLC und MALDI-TOF-Massenspektrmetrie identifiziert. Die Fermentationsmischung fördert die Immunität von Pflanzen gegen Bakterien und Virusinfektion. Die Zunahme der Immunität schwankt jedoch je nach System Pflanze-Pathogen. Die Fermentation von Chitosan durch Aspergillus fumigatus könnte eine schnelle und billige Methode zur Herstellung von Chitooligomeren mit guter Reinheit und Ausbeute sein. Eine partiell aufgereinigte Fermentationsmischung dieser Art könnte in der Landwirtschaft als Pathogeninhibitor genutzt werden. Durch kontrollierte Fermentation, die Chitooligomere in definierter Zusammensetzung (d.h. definierter Verteilung des Depolymerisationsgrades) liefert, könnte man zu Mischungen kommen, die für die jeweilige Anwendung eine optimale Bioaktivität besitzen. 3

  3. Verbesserung der Symmetrie von Hirnaufnahmen entlang der Sagittalebene

    NASA Astrophysics Data System (ADS)

    Ens, Konstantin; Wenzel, Fabian; Fischer, Bernd

    Die lokale Symmetrie von Hirnscans entlang der Sagittalebene zu ermitteln und zu modizifieren, ist für eine Reihe neurologischer Anwendungen interessant. Beispielsweise kann der voxelweise Vergleich von rechter und linker Hirnhälfte nur dann Aufschluss über die Lokalisierung von Läsionen geben, wenn durch Transformation ein Hirnscan eine möglichst hohe Symmetrie aufweist. Ein weiteres Anwendungsgebiet ist die Visualisierung von medialen Hirnschnitten, für die die Trennfläche beider Hirnhälfte möglichst eben sein sollte. Diese Arbeit stellt die Entwicklung eines Verfahrens vor, mit dessen Hilfe die Symmetrie von Hirnaufnahmen entlang der Sagittalebene verbessert werden kann. Dies geschieht unter Verwendung von aktiven Konturen, die mit Hilfe einer neuartigen Kostenfunktion gesteuert werden. Experimente am Ende der Arbeit mit strukturellen Kernspinaufnahmen demonstrieren die Leistungsfähigkeit des Verfahrens.

  4. Portrait of Dr. Von Braun with Walt Disney, 1954.

    NASA Technical Reports Server (NTRS)

    1954-01-01

    Marshall Center Director Dr. Wernher Von Braun is pictured with Walt Disney during a visit to the Marshall Space Flight Center in 1954. In the 1950s, Dr. Von Braun while working in California on the Saturn project, also worked with Disney studios as a technical director in making three films about Space Exploration for television. Disney's tour of Marshall in 1965 was Von Braun's hope for a renewed public interest in the future of the Space Program at NASA.

  5. Portrait of Dr. Von Braun with Walt Disney, 1954.

    NASA Technical Reports Server (NTRS)

    1954-01-01

    Marshall Center Director Dr. Wernher Von Braun is pictured with Walt Disney during a visit to the Marshall Space Flight Center in 1954. In the 1950s, Dr. Von Braun while working in California on the Saturn project, also worked with Disney studios as a technical director in making three films about Space Exploration for television. Disney's tour of Marshall in 1965 was Von Braun's hope for a renewed public interest in the future of the Space Program at NASA.

  6. Dr. von Braun and Army Ballistics Missile Agency (ABMA) Group

    NASA Technical Reports Server (NTRS)

    1959-01-01

    This photograph of Dr. von Braun, shown here to the left of General Bruce Medaris, was taken in the fall of 1959, immediately prior to Medaris' retirement from the Army. At the time, von Braun and his associates worked for the Army Ballistics Missile Agency in Huntsville, Alabama. Those in the photograph have been identified as Ernst Stuhlinger, Frederick von Saurma, Fritz Mueller, Hermarn Weidner, E.W. Neubert (partially hidden), W.A. Mrazek, Karl Heimburg, Arthur Rudolph, Otto Hoberg, von Braun, Oswald Lange, Medaris, Helmut Hoelzer, Hans Maus, E.D. Geissler, Hans Heuter, and George Constan.

  7. Measuring delusional ideation: the 21-item Peters et al. Delusions Inventory (PDI).

    PubMed

    Peters, Emmanuelle; Joseph, Stephen; Day, Samantha; Garety, Philippa

    2004-01-01

    There is increasing evidence that in the general population there are schizotypal traits and symptoms that can be measured psychometrically. Norms are reported for a new 21-item version of the Peters et al. Delusions Inventory (PDI; Peters et al. 1999b). The PDI, originally based on the Present State Examination, incorporates the multidimensionality of delusions by including measures of distress, preoccupation, and conviction. A total of 444 healthy individuals completed the 21-item PDI and two other questionnaires measuring florid delusions and social desirability. A subsample also filled out an in-depth schizotypal personality scale. Thirty-three deluded inpatients also completed the PDI. The PDI's psychometric properties confirmed that it remains a reliable and valid instrument to measure delusional ideation in the general population. Consistent with the 40-item PDI, it was normally distributed, no sex differences were found, and there was an inverse relationship with age. Individual items were endorsed by just over one in four healthy adults. Although the deluded sample scored significantly higher, the range of scores overlapped considerably, with 11 percent of healthy adults scoring higher than the mean of the deluded group. As with our previous findings, the two samples were differentiated by their ratings on the distress, preoccupation, and conviction scales. These results suggest that these dimensions may be more important than the content of belief alone for placing an individual on the continuum between normal and delusional thinking.

  8. Evolution of Capsaicinoids in Peter Pepper (Capsicum annuum var. annuum) During Fruit Ripening.

    PubMed

    Barbero, Gerardo F; de Aguiar, Ana C; Carrera, Ceferino; Olachea, Ángel; Ferreiro-González, Marta; Martínez, Julian; Palma, Miguel; Barroso, Carmelo G

    2016-08-01

    The evolution of individual and total contents of capsaicinoids present in Peter peppers (Capsicum annuum var. annuum) at different ripening stages has been studied. Plants were grown in a glasshouse and the new peppers were marked in a temporal space of ten days. The extraction of capsaicinoids was performed by ultrasound-assisted extraction with MeOH. The capsaicinoids nordihydrocapsaicin (n-DHC), capsaicin, dihydrocapsaicin, homocapsaicin, and homodihydrocapsaicin were analyzed by ultraperformance liquid chromatography (UHPLC)-fluorescence and identified by UHPLC-Q-ToF-MS. The results indicate that the total capsaicinoids increase in a linear manner from the first point of harvest at ten days (0.283 mg/g FW) up to 90 days, at which point they reach a concentration of 1.301 mg/g FW. The evolution as a percentage of the individual capsaicinoids showed the initial predominance of capsaicin, dihydrocapsaicin, and n-DHC. Dihydrocapsaicin was the major capsaicinoid up to day 50 of maturation. After 50 days, capsaicin became the major capsaicinoid as the concentration of dihydrocapsaicin fell slightly. The time of harvest of Peter pepper based on the total capsaicinoids content should be performed as late as possible. In any case, harvesting should be performed before overripening of the fruit is observed.

  9. Performance Evaluation Tests for Environmental Research (PETER): evaluation of 114 measures

    NASA Technical Reports Server (NTRS)

    Bittner, A. C. Jr; Carter, R. C.; Kennedy, R. S.; Harbeson, M. M.; Krause, M.

    1986-01-01

    The goal of the Performance Evaluation Tests for Environmental Research (PETER) Program was to identify a set of measures of human capabilities for use in the study of environmental and other time-course effects. 114 measures studied in the PETER Program were evaluated and categorized into four groups based upon task stability and task definition. The Recommended category contained 30 measures that clearly obtained total stabilization and had an acceptable level of reliability efficiency. The Acceptable-But-Redundant category contained 15 measures. The 37 measures in the Marginal category, which included an inordinate number of slope and other derived measures, usually had desirable features which were outweighed by faults. The 32 measures in the Unacceptable category had either differential instability or weak reliability efficiency. It is our opinion that the 30 measures in the Recommended category should be given first consideration for environmental research applications. Further, it is recommended that information pertaining to preexperimental practice requirements and stabilized reliabilities should be utilized in repeated-measures environmental studies.

  10. Lunatic Asylum in the Workhouse: St Peter's Hospital, Bristol, 1698-1861.

    PubMed

    Smith, Leonard

    2017-04-01

    In recent years there has been growing acknowledgement of the place of workhouses within the range of institutional provision for mentally disordered people in nineteenth-century England. This article explores the situation in Bristol, where an entrenched workhouse-based model was retained for an extended period in the face of mounting external ideological and political pressures to provide a proper lunatic asylum. It signified a contest between the modernising, reformist inclinations of central state agencies and local bodies seeking to retain their freedom of action. The conflict exposed contrasting conceptions regarding the nature of services to which the insane poor were entitled. Bristol pioneered establishment of a central workhouse under the old Poor Law; 'St Peter's Hospital' was opened in 1698. As a multi-purpose welfare institution its clientele included 'lunatics' and 'idiots', for whom there was specific accommodation from before the 1760s. Despite an unhealthy city centre location and crowded, dilapidated buildings, the enterprising Bristol authorities secured St Peter's Hospital's designation as a county lunatic asylum in 1823. Its many deficiencies brought condemnation in the national survey of provision for the insane in 1844. In the period following the key lunacy legislation of 1845, the Home Office and Commissioners in Lunacy demanded the replacement of the putative lunatic asylum within Bristol's workhouse by a new borough asylum outside the city. The Bristol authorities resisted stoutly for several years, but were eventually forced to succumb and adopt the prescribed model of institutional care for the pauper insane.

  11. Intravitreal Injection of Bevacizumab for Retinopathy of Prematurity in an Infant with Peters Anomaly

    PubMed Central

    Minami, Tsuyoshi; Kuniyoshi, Kazuki; Kusaka, Shunji; Sugioka, Koji; Sakuramoto, Hiroyuki; Sakamoto, Masuo; Izu, Akane; Wada, Norihisa; Shimomura, Yoshikazu

    2014-01-01

    Purpose To report our findings in an infant with Peters anomaly type II whose retinopathy of prematurity (ROP) was treated with an anti-VEGF agent and surgeries. Case Report A male infant weighing 548 g was born prematurely at 23 weeks and 1 day with corneal opacity and shallow anterior chambers in both eyes. At the postmenstrual age of 35 weeks and 3 days, the infant was tentatively diagnosed with stage 3 ROP because of a dilated tunica vasculosa lentis and ultrasonographic findings. The boy was treated with bilateral intravitreal injections of bevacizumab (IVB) because laser photocoagulation of the retina could not be performed due to the corneal opacity. The retina in the right eye detached 3 times, namely 5 days, 16 days, and 7 months after the IVB; encircling the scleral buckle and a vitrectomy with endolaser photocoagulation were therefore required. In his left eye, the retina was reattached after the initial IVB, and no additional treatment was required. ROP was not reactivated in both eyes until the last examination at the age of 2 years and 6 months. Conclusions Our results showed that IVB is a useful treatment for ROP in patients with Peters anomaly. However, a retinal detachment can be a complication after IVB. The optimal timing of IVB for ROP in infants with hazy media needs to be determined. PMID:25408672

  12. Performance Evaluation Tests for Environmental Research (PETER): evaluation of 114 measures

    NASA Technical Reports Server (NTRS)

    Bittner, A. C. Jr; Carter, R. C.; Kennedy, R. S.; Harbeson, M. M.; Krause, M.

    1986-01-01

    The goal of the Performance Evaluation Tests for Environmental Research (PETER) Program was to identify a set of measures of human capabilities for use in the study of environmental and other time-course effects. 114 measures studied in the PETER Program were evaluated and categorized into four groups based upon task stability and task definition. The Recommended category contained 30 measures that clearly obtained total stabilization and had an acceptable level of reliability efficiency. The Acceptable-But-Redundant category contained 15 measures. The 37 measures in the Marginal category, which included an inordinate number of slope and other derived measures, usually had desirable features which were outweighed by faults. The 32 measures in the Unacceptable category had either differential instability or weak reliability efficiency. It is our opinion that the 30 measures in the Recommended category should be given first consideration for environmental research applications. Further, it is recommended that information pertaining to preexperimental practice requirements and stabilized reliabilities should be utilized in repeated-measures environmental studies.

  13. PT2385 for the Treatment of Von Hippel-Lindau Disease-Associated Clear Cell Renal Cell Carcinoma

    ClinicalTrials.gov

    2017-04-04

    VHL Gene Mutation; VHL; VHL Syndrome; VHL Gene Inactivation; Von Hippel; Von Hippel-Lindau Disease; Von Hippel's Disease; Von Hippel-Lindau Syndrome, Modifiers of; Clear Cell Renal Cell Carcinoma; Clear Cell RCC; ccRCC

  14. Key contributors: Ernst von Glasersfeld's radical constructivism

    NASA Astrophysics Data System (ADS)

    Tobin, Kenneth

    2007-07-01

    This article reviews the significance of the contributions of Ernst von Glasersfeld to research in science education, especially through his theoretical contributions on radical constructivism. As a field shaper, Glasersfeld's subversive ideas catalyzed debate in the science education community and fuelled transformation of many facets including research methods, ways of thinking about teaching and learning, curriculum, and science teacher education. Perturbations emanating from the debates on constructivism forged new pathways that led to the development and use of many of the sociocultural frameworks employed by authors in Cultural Studies of Science Education.

  15. Approximating incompatible von Neumann measurements simultaneously

    SciTech Connect

    Heinosaari, Teiko; Jivulescu, Maria Anastasia; Reitzner, Daniel; Ziman, Mario

    2010-09-15

    We study the problem of performing orthogonal qubit measurements simultaneously. Since these measurements are incompatible, one has to accept additional imprecision. An optimal joint measurement is the one with the least possible imprecision. All earlier considerations of this problem have concerned only joint measurability of observables, while in this work we also take into account conditional state transformations (i.e., instruments). We characterize the optimal joint instrument for two orthogonal von Neumann instruments as being the Lueders instrument of the optimal joint observable.

  16. [Albrecht von Haller. An illustrious ancestor].

    PubMed

    Peiper, H-J

    2008-05-01

    Albrecht von Haller (1708-1777) was one of the most famous and important men of the eighteenth century. His achievements make him comparable with Lessing and Newton. In Blumenbach's opinion he was one of the enlightenment's greatest thinkers in both versatility and depth. He contributed significantly to developments in medicine, physiology, botany, pharmacology, theology, literature, editing, chronicles, biography, geography, and during his later years in Switzerland jurisprudence and agrarian reform. On the occasion of the 300th anniversary of his birth, important scientific landmarks in his life are described, with special attention to his achievements in the fields of anatomy, physiology, surgery, and experimental research.

  17. Acquired von Willebrand syndrome: von Willebrand factor propeptide to von Willebrand factor antigen ratio predicts remission status

    PubMed Central

    Lee, Adrienne; Sinclair, Gary; Valentine, Karen; James, Paula

    2014-01-01

    We investigated a case of acquired von Willebrand syndrome (AVWS) secondary to a nonneutralizing anti-von Willebrand factor (VWF) antibody associated with an autoimmune disorder. At diagnosis, VWF activity (VWF:Act), antigen (VWF:Ag), multimers, and factor VIII coagulant activity were virtually absent. VWF propeptide (VWFpp) was elevated with an infinitely high VWFpp to VWF:Ag ratio (VWFpp:Ag) consistent with rapid VWF clearance. Immunosuppressive treatment resulted in phenotypic remission 1 with normalization of VWF/factor VIII levels and multimer pattern. However, VWFpp:Ag remained elevated (∼2× normal), consistent with ongoing VWF clearance by the remaining anti-VWF antibody still present by enzyme-linked immunosorbent assay. This suggests that increased VWF secretion was compensating for the incomplete remission state. Relapse occurred when VWFpp:Ag was again infinitely high, with associated decreased VWFpp but unchanged anti-VWF titers; switching the balance to favor VWF clearance over secretion. Complete remission with undetectable anti-VWF occurred only when VWFpp:Ag was normal. This case of relapsing-remitting AVWS demonstrates the use of VWFpp:Ag for predicting remission status. PMID:24951428

  18. Rare liver tumor: symptomatic giant von Meyenburg complex

    PubMed Central

    Singh, Yardesh; Cawich, Shamir O.; Ramjit, Chunilal; Naraynsingh, Vijay

    2016-01-01

    von Meyenburg complexes are hamartomas that arise from intra-hepatic bile ducts. Symptomatic lesions are uncommon and giant lesions are exceedingly rare. When encountered, they should be excised because there are reports of malignant change in large, symptomatic lesions. We report a case of a symptomatic giant von Meyenburg complex. PMID:28068648

  19. Victor or Villain? Wernher von Braun and the Space Race

    ERIC Educational Resources Information Center

    O'Brien, Jason L.; Sears, Christine E.

    2011-01-01

    Set during the Cold War and space race, this historical role-play focuses on Wernher von Braun's involvement in and culpability for the use of slave laborers to produce V-2 rockets for Nazi Germany. Students will grapple with two central questions. Should von Braun have been allowed to emigrate to the United States given his affiliation with the…

  20. Victor or Villain? Wernher von Braun and the Space Race

    ERIC Educational Resources Information Center

    O'Brien, Jason L.; Sears, Christine E.

    2011-01-01

    Set during the Cold War and space race, this historical role-play focuses on Wernher von Braun's involvement in and culpability for the use of slave laborers to produce V-2 rockets for Nazi Germany. Students will grapple with two central questions. Should von Braun have been allowed to emigrate to the United States given his affiliation with the…

  1. A New Generalization of von Neumann Relative Entropy

    NASA Astrophysics Data System (ADS)

    Li, Jing; Cao, Huaixin

    2017-08-01

    In quantum information, von Neumann relative entropy has a great applications and operational interpretations in diverse fields, and von Neumann entropy is an important tool for describing the uncertainty of a quantum state. In this paper, we generalize the classical von Neumann relative entropy S(ρ||σ) and von Neumann entropy S(ρ) to f-von Neumann relative entropy \\widetilde {S}f(ρ ||σ ) and f-von Neumann entropy \\widetilde {S}f(ρ ) induced by a logarithm-like function f, respectively, and explore their properties. We prove that \\widetilde {S}f(ρ ||σ ) is nonnegative and then prove that \\widetilde {S}f(ρ ) has nonnegativity, boundedness, concavity, subadditivity and so on. Later, we show the stability and continuity of the \\widetilde {S}f(ρ ) with respect to the trace distance. In the case that f(x) = -log x, the resulted entropies reduce the classical von Neumann relative entropy and von Neumann entropy, respectively. This means that our results extend the usual results to a more general setting and then have some potential applications in quantum information.

  2. Group Theoretical Interpretation of von Neumann's Theorem on Composite Systems.

    ERIC Educational Resources Information Center

    Bergia, S.; And Others

    1979-01-01

    Shows that von Neumann's mathematical theorem on composite systems acquires a transparent physical meaning with reference to a suitable physical example; a composite system in a state of definite angular momentum. Gives an outline of the theorem, and the results are restated in Dirac's notation, thus generalizing von Neumann's results which were…

  3. Virtualized Optical Network (VON) for Future Internet and Applications

    NASA Astrophysics Data System (ADS)

    Jinno, Masahiko; Tsukishima, Yukio; Takara, Hidehiko; Kozicki, Bartlomiej; Sone, Yoshiaki; Sakano, Toshikazu

    A virtualized optical network (VON) is proposed as a key to implementing increased agility and flexibility into the future Internet and applications by providing any-to-any connectivity with the appropriate optical bandwidth at the appropriate time. The VON is enabled by introducing optical transparentization and optical fine granular grooming based on optical orthogonal frequency division multiplexing.

  4. Group Theoretical Interpretation of von Neumann's Theorem on Composite Systems.

    ERIC Educational Resources Information Center

    Bergia, S.; And Others

    1979-01-01

    Shows that von Neumann's mathematical theorem on composite systems acquires a transparent physical meaning with reference to a suitable physical example; a composite system in a state of definite angular momentum. Gives an outline of the theorem, and the results are restated in Dirac's notation, thus generalizing von Neumann's results which were…

  5. Dr. von Braun Tries Out the Neutral Buoyancy Simulator (NBS)

    NASA Technical Reports Server (NTRS)

    1967-01-01

    Marshall Space Flight Center (MSFC) Director, Dr. von Braun, submerges after spending some time under water in the MSFC Neutral Buoyancy Simulator (NBS). Weighted to a neutrally buoyant condition, Dr. von Braun was able to perform tasks underwater which simulated weightless conditions found in space.

  6. Dr. von Braun Tries Out the Neutral Buoyancy Simulator (NBS)

    NASA Technical Reports Server (NTRS)

    1967-01-01

    Astronaut L. Gordon Cooper checks the neck ring of a space suit worn by Marshall Space Flight Center (MSFC) Director, Dr. von Braun before he submerges into the water of the MSFC Neutral Buoyancy Simulator (NBS). Wearing a pressurized suit and weighted to a neutrally buoyant condition, Dr. von Braun was able to perform tasks underwater which simulated weightless conditions found in space.

  7. Dr. von Braun Tries Out the Neutral Buoyancy Simulator (NBS)

    NASA Technical Reports Server (NTRS)

    1967-01-01

    Marshall Space Flight Center (MSFC) Director, Dr. von Braun, is shown leaving the suiting-up van wearing a pressure suit prepared for a tryout in the MSFC Neutral Buoyancy Simulator (NBS). Weighted to a neutrally buoyant condition, Dr. von Braun was able to perform tasks underwater which simulated weightless conditions found in space.

  8. Wernher von Braun and Saturn IB on Launch Pad

    NASA Technical Reports Server (NTRS)

    1968-01-01

    Dr. Wernher von Braun stands in front of a Saturn IB launch vehicle at Kennedy Space Flight Center. Dr. von Braun led a team of German rocket scientists, called the Rocket Team, to the United States, first to Fort Bliss/White Sands, later being transferred to the Army Ballistic Missile Agency at Redstone Arsenal in Huntsville, Alabama. They were further transferred to the newly established NASA/Marshall Space Flight Center (MSFC) in Huntsville, Alabama in 1960, and Dr. von Braun became the first Center Director. Under von Braun's direction, MSFC developed the Mercury-Redstone, which put the first American in space; and later the Saturn rockets, Saturn I, Saturn IB, and Saturn V. The Saturn V launch vehicle put the first human on the surface of the Moon, and a modified Saturn V vehicle placed Skylab, the first United States' experimental space station, into Earth orbit. Dr. von Braun was MSFC Director from July 1960 to February 1970.

  9. Peter Singer and 'lives not worth living'--comments on a flawed argument from analogy.

    PubMed Central

    Sundström, P

    1995-01-01

    The Australian bioethicist Peter Singer has presented an intriguing argument for the opinion that it is quite proper (morally) to deem the lives of certain individuals not worth living and so to kill them. The argument is based on the alleged analogy between the ordinary clinical judgement that a life with a broken leg is worse than a life with an intact leg (other things being equal), and that the broken leg therefore ought to be mended, on the one hand, and the judgement that the lives of some individuals, for example, severely disabled infants, are not worth living and therefore ought to be terminated, on the other. In the present article it is argued that Singer's argument is flawed, intellectually and/or ethically. PMID:7776346

  10. Dr. Peter Cavanaugh Explains the Need and Operation of the FOOT Experiment

    NASA Technical Reports Server (NTRS)

    2003-01-01

    This video clip is an interview with Dr. Peter Cavanaugh, principal investigator for the FOOT experiment. He explains the reasoning behind the experiment and shows some video clips of the FOOT experiment being calibrated and conducted in orbit. The heart of the FOOT experiment is an instrumented suit called the Lower Extremity Monitoring Suit (LEMS). This customized garment is a pair of Lycra cycling tights incorporating 20 carefully placed sensors and the associated wiring control units, and amplifiers. LEMS enables the electrical activity of the muscles, the angular motions of the hip, knee, and ankle joints, and the force under both feet to be measured continuously. Measurements are also made on the arm muscles. Information from the sensors can be recorded up to 14 hours on a small, wearable computer.

  11. Common ground on surgical abortion?--engaging Peter Singer on the moral status of potential persons.

    PubMed

    Camosy, Charles C

    2008-12-01

    The debate over surgical abortion is certainly one of the most divisive in ethical discourse and for many it seems interminable. However, this paper argues that a primary reason for this is confusion with regard to what issues are actually under dispute. When looking at an entrenched and articulate figure on one side of the debate, Peter Singer, and comparing his views with those of his opponents, one finds that the disputed issue is actually quite a narrow one: the moral status of potential persons. Finding this common ground clears the conceptual space for a fruitful argument: the thesis of which is that most, including Singer, who argue that potential persons do not have full personal moral status fail to make the necessary distinction between natural potential (which confers moral status) and practical potential (which admittedly does not).

  12. Peter Singer and 'lives not worth living'--comments on a flawed argument from analogy.

    PubMed

    Sundström, P

    1995-02-01

    The Australian bioethicist Peter Singer has presented an intriguing argument for the opinion that it is quite proper (morally) to deem the lives of certain individuals not worth living and so to kill them. The argument is based on the alleged analogy between the ordinary clinical judgement that a life with a broken leg is worse than a life with an intact leg (other things being equal), and that the broken leg therefore ought to be mended, on the one hand, and the judgement that the lives of some individuals, for example, severely disabled infants, are not worth living and therefore ought to be terminated, on the other. In the present article it is argued that Singer's argument is flawed, intellectually and/or ethically.

  13. Sir Peter Medawar: science, creativity and the popularization of Karl Popper

    PubMed Central

    Calver, Neil

    2013-01-01

    Sir Peter Medawar was respected by scientists and literati alike. It was perhaps not surprising, then, that he would choose to involve himself in the ‘two cultures’ debate of 1959 and beyond. The focus of his intervention was the philosophy of Sir Karl Popper. However, Medawar's Popper was not the guru of falsification familiar from philosophy textbooks. Medawar's distinctive interpretation of Popper treated him instead as the source of insights into the role of creativity and imagination in scientific inquiry. This paper traces the context for Medawar's adoption of Popperian philosophy, together with its application before the debate. It then examines, within the context of the debate itself, the way in which Medawar attempted to reconcile scientific inquiry with literary practice. Medawar became increasingly convinced that not only was induction epistemologically unsound, but it was also damaging to the public role of the scientist. His construction of Popperianism would, he envisaged, provide a worthy alternative for scientists’ self-image.

  14. Peter Becker and his Nazi past: the man behind Becker muscular dystrophy and Becker myotonia.

    PubMed

    Zeidman, Lawrence A; Kondziella, Daniel

    2014-04-01

    Peter Becker was a German neurologist who helped classify the muscular dystrophies, and described Becker muscular dystrophy and Becker myotonia. His involvement in National Socialism began in 1933, when he was compelled by his peers to join the SA (brown shirts). He later joined the Nazi party, the Nazi Doctors Association, and the Nazi Lecturers' Association. He renewed his SA membership to maintain his position at a genetics institute. Colleagues stated postwar that he was not an active Nazi, and he was de-Nazified in 1947, able to continue his career. Later, Becker admitted to most, but not all, of his Nazi memberships in his autobiography, and wrote 2 books exploring the origins of Nazism and racial hygiene. The "neurologic court of opinion" must weigh in on how we should best remember Becker, and at the very least, we as neurologists must learn the dangers of career opportunism at any cost.

  15. Forensic psychiatry and the forensic sciences: in memory of Peter J. Batten, MD.

    PubMed

    Bloom, Joseph D

    2009-01-01

    This commentary is dedicated to the memory of Peter J. Batten, MD. He was a public health physician, a psychiatrist, and a medical examiner who spent his entire career in Salem, the capital of the State of Oregon. Salem was a unique place to work because, early in the history of Oregon, the state elected to build all of its original public institutions in the environs of the city. As the county medical examiner, Dr. Batten reviewed all questionable deaths that occurred within the county and in particular within the public institutions. Many of his findings were subsequently published, and these reports influenced the direction of mental health policy in these same institutions. He also used his position as county medical examiner to examine deaths in road rage incidents and those occurring at railroad crossings in Salem. The commentary also emphasizes the benefits of collaboration within the forensic sciences.

  16. Peter Bourne's drug policy and the perils of a public health ethic, 1976-1978.

    PubMed

    Clark, Claire D; Dufton, Emily

    2015-02-01

    As President Jimmy Carter's advisor for health issues, Peter Bourne promoted a rational and comprehensive drug strategy that combined new supply-side efforts to prevent drug use with previously established demand-side addiction treatment programs. Using a public health ethic that allowed the impact of substances on overall population health to guide drug control, Bourne advocated for marijuana decriminalization as well as increased regulations for barbiturates. A hostile political climate, a series of rumors, and pressure from both drug legalizers and prohibitionists caused Bourne to resign in disgrace in 1978. We argue that Bourne's critics used his own public health framework to challenge him, describe the health critiques that contributed to Bourne's resignation, and present the story of his departure as a cautionary tale for today's drug policy reformers.

  17. The man in the scarlet cloak. The mysterious death of Peter Anthony Motteux.

    PubMed

    Ober, W B

    1991-09-01

    Peter Anthony Motteux (1663-1718), a Huguenot refugee in London, established a literary reputation by completing Sir Thomas Urquhart's translation of Rabelais' Gargantua and Pantagruel, then Cervantes' Don Quixote. He later became an import-export merchant. On his 55th birthday he donned his scarlet cloak and went out on the town. He picked up a prostitute and after some dalliance returned to her bordello. Shortly thereafter he was found dead, although the evidence is that he was in good health when he arrived. Literary evidence is that he died from assisted erotic asphyxia, a variant of autoerotic asphyxia, cf. the case of Frantisek Koczwara (Am J Forensic Med Pathol 5:145-149, 1984.)

  18. Yes! There is an ethics of care: an answer for Peter Allmark.

    PubMed Central

    Bradshaw, A

    1996-01-01

    This paper is a response to Peter Allmark's thesis that 'there can be no "caring" ethics'. It argues that the current preoccupation in nursing to define an ethics of care is a direct result of breaking nursing tradition. Subsequent attempts to find a moral basis for care, whether from subjective experimental perspectives such as described by Noddings, or from rational and detached approaches derived from Kant, are inevitably flawed. Writers may still implicitly presuppose a concept of care drawn from the Judaeo-Christian tradition but without explicit recourse to its moral basis nursing is left rudderless and potentially without purpose. The very concept of 'care' cut off from its roots becomes a meaningless term without either normative or descriptive content. PMID:8932719

  19. SUSY structures, representations and Peter-Weyl theorem for S 1 | 1

    NASA Astrophysics Data System (ADS)

    Carmeli, C.; Fioresi, R.; Kwok, S.

    2015-09-01

    The real compact supergroup S 1 | 1 is analysed from different perspectives and its representation theory is studied. We prove it is the only (up to isomorphism) supergroup, which is a real form of (C 1 | 1) × with reduced Lie group S1, and a link with SUSY structures on C 1 | 1 is established. We describe a large family of complex semisimple representations of S 1 | 1 and we show that any S 1 | 1-representation whose weights are all nonzero is a direct sum of members of our family. We also compute the matrix elements of the members of this family and we give a proof of the Peter-Weyl theorem for S 1 | 1.

  20. Analyses and description of geochemical samples, Peters Mountain Wilderness Study Area, Giles County, Virginia

    USGS Publications Warehouse

    Rait, Norma; Lesure, Frank Gardner

    1978-01-01

    Semiquantitative emission spectrographic analyses for 64 elements on 43 stream sediment and 73 rock samples from Peters Mountain Wilderness Study area, Giles County, Virginia, are reported here in detail. Locations for all samples are in Universal Transverse Mercator (UTM) coordinates. Brie[ descriptions of rock samples are also included. Rocks analysed are mostly sandstone. Samples of hematitic sandstone of the Rose Hill Formation and limonite-cemented sandstone of the Rocky Gap Sandstone contain high values of iron; these rocks are submarginal iron resources. Some of the same iron-rich samples have a little more barium, copper, cobalt, lead, silver, and/or zinc then average sandstone, but they do not suggest the presence of economic deposits of these metals. No other obviously anomalous values related to mineralized rock are present in the data.

  1. Acute toxicity and toxic interaction of chromium and nickel to common guppy Poecilia reticulata (Peters)

    SciTech Connect

    Khangarot, B.S.; Ray, P.K. )

    1990-06-01

    The acute toxicity of heavy metals in combination to the common guppy has been reported. Information on the combined effects of chromium and nickel to fish is rather scarce. Toxicity of nickel and chromium to fish is generally low. These two elements are usually less toxic than silver, cadmium, copper and thallium; depending on test conditions, these may also be less hazardous than zinc, lead and arsenic. The present study was undertaken to investigate the acute toxicity of Ni and Cr singly and the toxic interaction of these two metal ions on survival of the common guppy, Poecilia reticulata (Peters). This species was selected for static bioassays because it can be easily cultured and raised under laboratory conditions through a complete life cycle, and it is one of the most common fish used for laboratory toxicity studies.

  2. "The physician as poet" review of: Pereira, Peter Saying the World

    PubMed Central

    Weishaus, Joel

    2006-01-01

    Peter Pereira is a family physician and a poet. I weave excerpts from Dr. Pereira's poems into a brief history of medicine's mythological and historical roots, beginning with the Egyptian god Thoth, and the Greek physician Hippocrates. Along the way, I touch on the European Middle Ages and the Islamic World. Finally, I quote poet-critic T.S. Eliot, who was an early influence on Dr. Pereira's decision to become a poet, and contemporary physician-poets Rafael Campo and William Carlos Williams. I end by placing Dr. Pereira, whose practice is oriented toward immigrant families, in his indigenous Pacific Northwest, arguing that being both physician and poet helps Pereira to live in a world that is both intimately human and naturally impersonal.

  3. Yes! There is an ethics of care: an answer for Peter Allmark.

    PubMed

    Bradshaw, A

    1996-02-01

    This paper is a response to Peter Allmark's thesis that 'there can be no "caring" ethics'. It argues that the current preoccupation in nursing to define an ethics of care is a direct result of breaking nursing tradition. Subsequent attempts to find a moral basis for care, whether from subjective experimental perspectives such as described by Noddings, or from rational and detached approaches derived from Kant, are inevitably flawed. Writers may still implicitly presuppose a concept of care drawn from the Judaeo-Christian tradition but without explicit recourse to its moral basis nursing is left rudderless and potentially without purpose. The very concept of 'care' cut off from its roots becomes a meaningless term without either normative or descriptive content.

  4. Dr. Peter Cavanaugh Explains the Need and Operation of the FOOT Experiment

    NASA Technical Reports Server (NTRS)

    2003-01-01

    This video clip is an interview with Dr. Peter Cavanaugh, principal investigator for the FOOT experiment. He explains the reasoning behind the experiment and shows some video clips of the FOOT experiment being calibrated and conducted in orbit. The heart of the FOOT experiment is an instrumented suit called the Lower Extremity Monitoring Suit (LEMS). This customized garment is a pair of Lycra cycling tights incorporating 20 carefully placed sensors and the associated wiring control units, and amplifiers. LEMS enables the electrical activity of the muscles, the angular motions of the hip, knee, and ankle joints, and the force under both feet to be measured continuously. Measurements are also made on the arm muscles. Information from the sensors can be recorded up to 14 hours on a small, wearable computer.

  5. Influence of depositional environment and diagenesis on gas reservoir properties in St. Peter Sandstone, Michigan basin

    SciTech Connect

    Harrison, W.B. III; Turmelle, T.M.; Barnes, D.A.

    1987-05-01

    The St. Peter Sandstone in the Michigan basin subsurface is rapidly becoming a major exploration target for natural gas. This reservoir was first proven with the successful completion of the Dart-Edwards 7-36 (Falmouth field, Missaukee County, Michigan) in 1981. Fifteen fields now are known, with a maximum of three producing wells in any one field. The production from these wells ranges from 1 to more than 10 MMCFGD on choke, with light-gravity condensate production of up to 450 b/d. Depth to the producing intervals ranges from about 7000 ft to more than 11,000 ft. The St. Peter Sandstone is an amalgamated stack of shoreface and shelf sequences more than 1100 ft in thickness in the basin center and thinning to zero at the basin margins. Sandstone composition varies from quartzarenite in the coarser sizes to subarkose and arkose in the finer sizes. Thin salty/shaly lithologies and dolomite-cemented sandstone intervals separate the porous sandstone packages. Two major lithofacies are recognized in the basin: a coarse-grained, well-sorted quartzarenite with various current laminations and a fine-grained, more poorly sorted subarkose and arkose with abundant bioturbation and distinct vertical and horizontal burrows. Reservoir quality is influenced by original depositional and diagenetic fabrics, but there is inversion of permeability and porosity with respect to primary textures in the major lithofacies. The initially highly porous and permeable, well-sorted, coarser facies is now tightly cemented with syntaxial quartz cement, resulting in a low-permeability, poor quality reservoir. The more poorly sorted, finer facies with initially lower permeabilities did not receive significant fluid flux until it passed below the zone of quartz cementation. This facies was cemented with carbonate which has subsequently dissolved to form a major secondary porosity reservoir.

  6. The search for asbestos within the Peter Mitchell Taconite iron ore mine, near Babbitt, Minnesota.

    PubMed

    Ross, Malcolm; Nolan, Robert P; Nord, Gordon L

    2008-10-01

    Asbestos crystallizes within rock formations undergoing intense deformation characterized by folding, faulting, shearing, and dilation. Some of these conditions have prevailed during formation of the taconite iron ore deposits in the eastern Mesabi Iron Range of Minnesota. This range includes the Peter Mitchell Taconite Mine at Babbitt, Minnesota. The mine pit is over 8 miles long, up to 1 mile wide. Fifty three samples were collected from 30 sites within areas of the pit where faulting, shearing and folding occur and where fibrous minerals might occur. Eight samples from seven collecting sites contain significant amounts of ferroactinolite amphibole that is partially to completely altered to fibrous ferroactinolite. Two samples from two other sites contain ferroactinolite degraded to ropy masses of fibers consisting mostly of ferrian sepiolite as defined by X-ray diffraction and TEM and SEM X-ray spectral analysis. Samples from five other sites contain unaltered amphiboles, however some of these samples also contain a very small number of fiber bundles composed of mixtures of grunerite, ferroactinolite, and ferrian sepiolite. It is proposed that the alteration of the amphiboles was caused by reaction with water-rich acidic fluids that moved through the mine faults and shear zones. The fibrous amphiboles and ferrian sepiolite collected at the Peter Mitchell Mine composes a tiny fraction of one percent of the total rock mass of this taconite deposit; an even a smaller amount of these mineral fragments enter the ambient air during mining and milling. These fibrous minerals thus do not present a significant health hazard to the miners nor to those non-occupationally exposed. No asbestos of any type was found in the mine pit.

  7. Remelting and Remobilization in a Magmatic Arc: the St Peter Suite, South Australia

    NASA Astrophysics Data System (ADS)

    Symington, Neil; Weinberg, Roberto; Hasalová, Pavlina

    2014-05-01

    Thermo-mechanical models of magmatic arcs suggest that intermittent intrusion of magma batches should lead to remelting and remobilization of earlier intrusive rocks as a result of fluctuations in temperature and water content. However, examples of remelting and remobilization of earlier intrusive rocks, formed during arc-building, are surprisingly rare. We investigate the evolution of magmatic rocks of the Palaeoproterozoic St Peter Suite, in the Gawler Craton, South Australia. This suite records multiple intrusions, magma hybridization, and the remelting and remobilization of these intrusions to form migmatites and newly-formed leucocratic magmas. In this paper we detail first how multiple magma batches interact with one another as liquids and mushes during syn-magmatic deformation phases, and then detail the nature of migmatites resulting from anatexis of these same magmatic rocks and the resulting channel ways that allowed for magma remobilization. LA-ICP/MS U/Pb zircon dating yielded crystallization ages of 1647±12 Ma for an early diorite-to-granite suite, and 1604±12 Ma for a later magmatic suite of broadly similar composition. Both these suites underwent anatectic events. Titanite from late-formed leucosomes found within D2 shear zones in the older suite, yielded SHRIMP U/Pb age of 1605±7 Ma, within error of the age of the younger suite. We therefore infer that intrusion, crystallization and remelting/remobilization of this younger suite of rocks occurred within 10-15 M.yr. Thus, the St Peter Suite exposures record many of the key processes expected in arcs, including the prediction that early intrusive arc rocks remelt to form younger more fractionated magmas.

  8. On the Versatility of von Willebrand Factor

    PubMed Central

    Rauch, Antoine; Wohner, Nikolett; Christophe, Olivier D.; Denis, Cécile V.; Susen, Sophie; Lenting, Peter J.

    2013-01-01

    Von Willebrand factor (VWF) is a large multimeric protein, the function of which has been demonstrated to be pivotal to the haemostatic system. Indeed, quantitative and/or qualitative abnormalities of VWF are associated with the bleeding disorder Von Willebrand disease (VWD). Moreover, increased plasma concentrations of VWF have been linked to an increased risk for thrombotic complications. In the previous decades, many studies have contributed to our understanding of how VWF is connected to the haemostatic system, particularly with regard to structure-function relationships. Interactive sites for important ligands of VWF (such as factor VIII, collagen, glycoprotein Ibα, integrin αIIbβ3 and protease ADAMTS13) have been identified, and mutagenesis studies have confirmed the physiological relevance of the interactions between VWF and these ligands. However, we have also become aware that VWF has a more versatile character than previously thought, given its potential role in various non-hemostatic processes, like intimal thickening, tumor cell apoptosis and inflammatory processes. In the presence review, a summary of our knowledge on VWF structure-function relationships is provided in the context of the “classical” haemostatic task of VWF and in perspective of pathological processes beyond haemostasis. PMID:23936617

  9. Von Neumann's quantization of general relativity

    NASA Astrophysics Data System (ADS)

    Arbuzov, A. B.; Cherny, A. Yu.; Cirilo-Lombardo, D. J.; Nazmitdinov, R. G.; Han, Nguyen Suan; Pavlov, A. E.; Pervushin, V. N.; Zakharov, A. F.

    2017-05-01

    Von Neumann's procedure is applied to quantizing general relativity. Initial data for dynamical variables in the Planck epoch, where the Hubble parameter value coincided with the Planck mass are quantized. These initial data are defined in terms of the Fock orthogonal simplex in the tangent Minkowski spacetime and the Dirac conformal interval. The Einstein cosmological principle is used to average the logarithm of the determinant of the spatial metric over the spatial volume of the visible Universe. The splitting of general coordinate transformations into diffeomorphisms and transformations of the initial data is introduced. In accordance with von Neumann's procedure, the vacuum state is treated is a quantum ensemble that is degenerate in quantum numbers of nonvacuum states. The distribution of the vacuum state leads to the Casimir effect in gravidynamics in just the same way as in electrodynamics. The generating functional for perturbation theory in gravidynamics is found by solving the quantum energy constraint. The applicability range of gravidynamics is discussed along with the possibility of employing this theory to interpret modern observational data.

  10. Molecular diagnosis of von Willebrand disease.

    PubMed

    Baronciani, L; Goodeve, A; Peyvandi, F

    2017-03-01

    The role of molecular characterization in the diagnosis of von Willebrand disease (VWD) is not essential if the patients have been extensively investigated using phenotypic analysis. On the other hand, if some of these phenotype assays are not available, the identification of the mutation causing the disease could be crucial for an accurate diagnosis. Nevertheless, there are several reasons for performing molecular analysis in patients phenotypically well characterized, e.g. to identify the mutation causing VWD can be useful for patients and their family members when prenatal diagnosis is required (type 3 or severe type 2). In this manuscript, we report the techniques used for the molecular characterization of suspected VWD patients. We describe the use of online von Willebrand factor database and online single nucleotide variation databases, the former to verify whether a candidate mutation has been previously identified in other VWD patients and the latter to ascertain whether a putative mutation has been reported earlier in healthy individuals. We listed the available in silico analysis tools, to determine the predicted pathogenicity of a sequence variant and to establish its possible negative effect on the normal splicing process. We also report the strategy that can be used to identify VWD type 2 patients' mutations in subjects who have been fully characterized using the phenotype assays.

  11. Report on von Willebrand Disease in Malaysia

    PubMed Central

    Periayah, Mercy Halleluyah; Halim, Ahmad Sukari; Saad, Arman Zaharil Mat; Yaacob, Nik Soriani; Karim, Faraizah Abdul

    2016-01-01

    BACKGROUND: Von Willebrand disease (vWD) is an inherited hemostatic disorder that affects the hemostasis pathway. The worldwide prevalence of vWD is estimated to be 1% of the general population but only 0.002% in Malaysia. AIM: Our present paper has been written to disclose the statistical counts on the number of vWD cases reported from 2011 to 2013. MATERIAL AND METHODS: This article is based on sociodemographic data, diagnoses and laboratory findings of vWD in Malaysia. A total of 92 patients were reported to have vWD in Malaysia from 2011 to 2013. RESULTS: Sociodemographic-analysis revealed that 60% were females, 63% were of the Malay ethnicity, 41.3% were in the 19-44 year old age group and 15.2% were from Sabah, with the East region having the highest registered number of vWD cases. In Malaysia, most patients are predominately affected by vWD type 1 (77.2%). Factor 8, von Willebrand factor: Antigen and vWF: Collagen-Binding was the strongest determinants in the laboratory profiles of vWD. CONCLUSION: This report has been done with great interest to provide an immense contribution from Malaysia, by revealing the statistical counts on vWD from 2011-2013. PMID:27275342

  12. Approximate von Neumann entropy for directed graphs.

    PubMed

    Ye, Cheng; Wilson, Richard C; Comin, César H; Costa, Luciano da F; Hancock, Edwin R

    2014-05-01

    In this paper, we develop an entropy measure for assessing the structural complexity of directed graphs. Although there are many existing alternative measures for quantifying the structural properties of undirected graphs, there are relatively few corresponding measures for directed graphs. To fill this gap in the literature, we explore an alternative technique that is applicable to directed graphs. We commence by using Chung's generalization of the Laplacian of a directed graph to extend the computation of von Neumann entropy from undirected to directed graphs. We provide a simplified form of the entropy which can be expressed in terms of simple node in-degree and out-degree statistics. Moreover, we find approximate forms of the von Neumann entropy that apply to both weakly and strongly directed graphs, and that can be used to characterize network structure. We illustrate the usefulness of these simplified entropy forms defined in this paper on both artificial and real-world data sets, including structures from protein databases and high energy physics theory citation networks.

  13. Rethinking the diagnosis of von Willebrand disease.

    PubMed

    Favaloro, Emmanuel J

    2011-01-01

    von Willebrand disease (VWD) is the most common inherited bleeding disorder and arises from deficiencies and/or defects in the plasma protein von Willebrand factor (VWF). VWD is classified into 6 different types, with type 1 identified as a (partial) quantitative deficiency of VWF, type 3 defined by a (virtual) total deficiency of VWF, and type 2 identifying four separate types (2A, 2B, 2M, 2N) characterised by qualitative defects. The classification is based on phenotypic assays including FVIII, VWF:Ag and VWF activity, typically by ristocetin cofactor (VWF:RCo), but also increasingly by collagen binding (VWF:CB). Phenotypic testing may be supplemented by multimer analysis, RIPA, and VWF:FVIII binding. Although genetic analysis is not required to diagnose VWD or to define a classification type, it may be useful in discrete situations. The current review briefly covers this diagnostic process, with a focus on newer approaches, including extended test panels and the use of data from desmopressin challenges as a diagnostic tool. Copyright © 2011 Elsevier Ltd. All rights reserved.

  14. Writing the True Self: Case Studies of Eng 101 Students Responding to a Peter Elbow-Inspired Curriculum

    ERIC Educational Resources Information Center

    Stansell, Jon W.

    2012-01-01

    My fulfillment in life comes through helping others develop their potential, work through their troubles, and follow their dreams. I have found that my college students embrace this aspect as I teach them expressive, author-involved writing. Peter Elbow's work asserts that this type of writing fits into his theory of personal development, which is…

  15. 76 FR 13271 - Gulf & Ohio Railways, Inc., H. Peter Claussen and Linda C. Claussen-Continuance in Control...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION Surface Transportation Board Gulf & Ohio Railways, Inc., H. Peter Claussen and Linda C. Claussen--Continuance in Control Exemption--Lancaster & Chester Railroad, LLC AGENCY: Surface Transportation Board, DOT...

  16. Pratt & Whitney Advanced Ducted Propulsor (ADP) Engine Test in 40x80ft w.t.: Engineers Peter

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Pratt & Whitney Advanced Ducted Propulsor (ADP) Engine Test in 40x80ft w.t.: Engineers Peter Zell (left) and Dr Clifton Horne (right) are shown preparing a laser light sheet for a flow visualization test. Shown standing in the nacelle of the ADP is John Girvin, senior test engineer for Pratt & Whitney.

  17. Pratt & Whitney Advanced Ducted Propulsor (ADP) Engine Test in 40x80ft w.t.: Engineers Peter

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Pratt & Whitney Advanced Ducted Propulsor (ADP) Engine Test in 40x80ft w.t.: Engineers Peter Zell (left) and Dr Clifton Horne (right) are shown preparing for a laser light sheet for a flow visualization test. Shown standing in the nacelle of the ADP is John Girvin, senior test engineer for Pratt & Whitney.

  18. Split Attention as Part of a Flexible Attentional System for Complex Scenes: Comment on Jans, Peters, and De Weerd (2010)

    ERIC Educational Resources Information Center

    Cave, Kyle R.; Bush, William S.; Taylor, Thalia G. G.

    2010-01-01

    Jans, Peters, and De Weerd (2010) examined the studies demonstrating that spatial attention can be split across 2 noncontiguous target locations. They find all these studies to be flawed and conclude that spatial attention only selects a single location at any given time. They do, however, suggest that there could be exceptional circumstances that…

  19. Communication; A Discussion at the Nobel Conference (5th, Gustavus Adolphus College, St. Peter, Minnesota, January 8-9, 1969).

    ERIC Educational Resources Information Center

    Roslansky, John D., Ed.

    This book consists of five lectures on communication given at the fifth Nobel Conference. Leroy G. Augenstein explores the positive and negative consequences of man's increasing capacity to manipulate and control the human mind. Peter Marler demonstrates that all the elements necessary for a communication system to qualify as a language exist…

  20. On the Search for Regularities in Studies of School Effectiveness and Improvement: Some Comments on Peter Tymms' Comments.

    ERIC Educational Resources Information Center

    Gray, John; And Others

    1995-01-01

    School-effectiveness researchers have had difficulty quantifying stability in effectiveness over time. Responding to Peter Tymms's argument that Gray and associates have not provided an authoritative statistical analysis of school effectiveness (in a study of 30 British secondary schools), this article asserts that this study was concerned with…

  1. Communication; A Discussion at the Nobel Conference (5th, Gustavus Adolphus College, St. Peter, Minnesota, January 8-9, 1969).

    ERIC Educational Resources Information Center

    Roslansky, John D., Ed.

    This book consists of five lectures on communication given at the fifth Nobel Conference. Leroy G. Augenstein explores the positive and negative consequences of man's increasing capacity to manipulate and control the human mind. Peter Marler demonstrates that all the elements necessary for a communication system to qualify as a language exist…

  2. Teaching, Learning and Education in Late Modernity: The Selected Works of Peter Jarvis. World Library of Educationalists

    ERIC Educational Resources Information Center

    Jarvis, Peter

    2011-01-01

    Professor Peter Jarvis has spent over 30 years researching, thinking and writing about some of the key and enduring issues in education. He has contributed well over 30 books and 200 papers and chapters in books on learning theory, adult education and learning, continuing professional education, nurse education, primary school education, distance…

  3. The Global Food Crisis: Causes and Solutions. Statement of Peter McPherson before the Senate Foreign Relations Committee

    ERIC Educational Resources Information Center

    National Association of State Universities and Land-Grant Colleges, 2008

    2008-01-01

    This paper presents Peter McPherson's statement before the Senate Foreign Relations Committee. He begins by saying that people have an immediate problem that must be addressed, hopefully in a way that does not complicate long-term solutions. They also have a long-term and more complicated agricultural problem that the world has neglected over many…

  4. Peter Fensham--Head, Heart and Hands (on) in the Service of Science Education and Social Equity and Justice

    ERIC Educational Resources Information Center

    Gunstone, Richard

    2009-01-01

    When Peter Fensham was appointed to the new Chair of Science Education at Monash University in 1967 he was the first Professor of Science Education in Australia, and, we think, may well have been the first such professor anywhere in the world outside USA. Over the subsequent 40+ years he has made/still makes remarkable and diverse contributions to…

  5. Serials Management in the Electronic Era: Papers in Honor of Peter Gellatly, Founding Editor of "The Serials Librarian."

    ERIC Educational Resources Information Center

    Cole, Jim, Ed.; Williams, James W., Ed.

    This book assesses progress and technical changes in the field of serials management and anticipates future directions and challenges for librarians. The book consists of 18 chapters: (1) "Introduction" (Jim Cole and James W. Williams); (2) "Peter Gellatly--Editor with a Deft Touch" (Ruth C. Carter); (3) "The "Deseret…

  6. Saving Time and Money in Michigan: Peter J. Young Talks about Professional Development, Parent Communication, Funding, and Partnerships

    ERIC Educational Resources Information Center

    Branzburg, Jeffrey

    2007-01-01

    This article presents an interview with Peter J. Young, Director of Technology at Rockford Public Schools in Michigan. In the interview, Young talked about how his district has done a lot more automation to integrate its disparate systems. He also discussed how they streamline their systems, how parents and community benefit from these efforts,…

  7. Saving Time and Money in Michigan: Peter J. Young Talks about Professional Development, Parent Communication, Funding, and Partnerships

    ERIC Educational Resources Information Center

    Branzburg, Jeffrey

    2007-01-01

    This article presents an interview with Peter J. Young, Director of Technology at Rockford Public Schools in Michigan. In the interview, Young talked about how his district has done a lot more automation to integrate its disparate systems. He also discussed how they streamline their systems, how parents and community benefit from these efforts,…

  8. Writing the True Self: Case Studies of Eng 101 Students Responding to a Peter Elbow-Inspired Curriculum

    ERIC Educational Resources Information Center

    Stansell, Jon W.

    2012-01-01

    My fulfillment in life comes through helping others develop their potential, work through their troubles, and follow their dreams. I have found that my college students embrace this aspect as I teach them expressive, author-involved writing. Peter Elbow's work asserts that this type of writing fits into his theory of personal development, which is…

  9. St. Peter's reclaims its identity in the face of rapid growth. Two-year process results in new name.

    PubMed

    Botvin, J D

    2001-01-01

    A 130-year-old, well-respected Albany, N.Y., hospital, St. Peter's, experienced growing pains as it became a system comprising 25 entities. We describe a branding initiative carefully designed to identify the new health care system with the "old friend."

  10. Serials Management in the Electronic Era: Papers in Honor of Peter Gellatly, Founding Editor of "The Serials Librarian."

    ERIC Educational Resources Information Center

    Cole, Jim, Ed.; Williams, James W., Ed.

    This book assesses progress and technical changes in the field of serials management and anticipates future directions and challenges for librarians. The book consists of 18 chapters: (1) "Introduction" (Jim Cole and James W. Williams); (2) "Peter Gellatly--Editor with a Deft Touch" (Ruth C. Carter); (3) "The "Deseret…

  11. BOOK REVIEW: Meilensteine der Astronomie - Von Aristoteles bis Hawking

    NASA Astrophysics Data System (ADS)

    Duerbeck, H. W.; Hamel, J.

    2006-12-01

    A writer, more specific a writer on the history of astronomy, might from time to time look at the collected document folders with all the research material and reprints, and might wonder: has this been all? Especially at a time when recycling is in vogue? And, perhaps with a request or an invitation to submit something, he or she might consider re-using the material before its definitive disposal. Well, such are my feelings when I looked at Jurgen Hamel's new book Milestones of Astronomy - From Aristoteles to Hawking . A slight chance for survival of medium-sized publishers like Kosmos is to offer popular books, and a title must attract potential buyers: Aristoteles means the "old" times, and as concerns the "mad scientist" of modern times, Stephen Hawking has by now dethroned Einstein. In 1998, Hamel had published a Geschichte der Astronomie - Von den Anfangen bis zur Gegenwart (History of astronomy, from the beginnings to the present), which, of course, he could not simply copy. This time, he selected some stones from his research areas - milestones, touchstones, stumbling blocks in the long road of astronomical evolution - and put them between the covers of his new book. So let us look at these (mile)stones . The reader is informed about Aristoteles on 2 pages, but his medieval interpreter Johannes de Sacrobosco gets 8 pages! Copernicus' life and achievements are described on 9 pages, closely followed by his devotee and translator Rothmann with 8 pages; Copernicus' contemporary, Peter Apian, however, gets about 13! Bessel's and Herschel's lifes and works are described on well-deserved 13 and 15 pages, while the achievements of the two Lucasian professors, Isaac Newton and Stephen Hawking, are just outlined in a single paragraph! Thus, importance is sometimes inversely proportional to text length... But let us become serious now. Why should an active historian outline, for the hundreth time, the life of Copernicus, while there are so many interesting, and often

  12. Two novel anti-von Willebrand factor monoclonal antibodies.

    PubMed

    Spadafora-Ferreira, M; Lopes, A A; Coelho, V; Guilherme, L; Kalil, J

    2000-01-15

    Von Willebrand Factor is a multimer produced by endothelial cells and megakaryocytes, being stored in intracellular organelles, such as the Weibel-Palade bodies and alpha-granules in endothelial cells and platelets, respectively. This molecule acts as a carrier protein for factor VIIIc, involved in the intrinsic pathway of blood coagulation maintaining its stability in circulation. Von Willebrand Factor also plays an important role in platelet aggregation and adhesion to injured vessel wall. It interacts with platelets through two distinct glycoproteins, GPIb and GPIIb/IIIa. We raised two monoclonal antibodies, ECA-3 and ECA-4, against human umbilical vascular endothelial cells that recognize and immunoprecipitate von Willebrand Factor. Interestingly, ECA-4 monoclonal antibody is able to completely inhibit platelet agglutination induced by ristocetin, suggesting that it binds to von Willebrand Factor close to platelet GPIb binding site. The use of monoclonal antibodies to identify von Willebrand Factor binding regions to factor VIII or platelets has been reported by others. In pulmonary hypertension, abnormalities have been detected on the multimeric structure of the molecule as well as on its proteolytic fragments, by using monoclonal antibodies. Moreover, monoclonal antibodies raised against specific regions of von Willebrand Factor molecule may allow studies of functional abnormalities of this protein in inherited and acquired disorders like subtypes of von Willebrand's disease.

  13. Interactions of von Willebrand factor and ADAMTS13 in von Willebrand disease and thrombotic thrombocytopenic purpura.

    PubMed

    Budde, U; Schneppenheim, R

    2014-01-01

    The function of von Willebrand factor (VWF), a huge multimeric protein and a key factor in platelet dependent primary haemostasis, is regulated by its specific protease ADAMTS13. The ADAMTS13 dependent degradation of VWF to its proteolytic fragments can be visualized as a characteristic so-called triplet structure of individual VWF oligomers by multimer analysis. Lack of VWF high molecular weight multimers (VWF-HMWM) or their pathologically enhanced degradation underlies a particular type of von Willebrand disease, VWD type 2A with a significant bleeding tendency, and may also be observed in acquired von Willebrand syndrome due to cardiovascular disease. In these conditions multimer analysis is an obligatory and powerful tool for diagnosis of VWD. The opposite condition, the persistence of ultralarge VWF (UL-VWF) multimers may cause the microangiopathic life-threatening disorder thrombotic thrombocytopenic purpura (TTP). During the course of active TTP, UL-VWF is consumed in the hyaline thrombi formed in the microvasculature which will ultimately result in the loss of UL-VWF and VWF-HMWM. Therefore, VWF multimer analysis is not a valid tool to diagnose TTP in the active phase of disease but may be helpful for the diagnosis of TTP patients in remission.

  14. Utilization of the St. Peter Sandstone in the Illinois Basin for CO2 Sequestration

    SciTech Connect

    Will, Robert; Smith, Valerie; Leetaru, Hannes

    2014-09-30

    This project is part of a larger project co-funded by the United States Department of Energy (US DOE) under cooperative agreement DE-FE0002068 from 12/08/2009 through 9/31/2014. The study is to evaluate the potential of formations within the Cambro-Ordovician strata above the Mt. Simon Sandstone as potential targets for carbon dioxide (CO2) sequestration in the Illinois and Michigan Basins. This report evaluates the potential injectivity of the Ordovician St. Peter Sandstone. The evaluation of this formation was accomplished using wireline data, core data, pressure data, and seismic data acquired through funding in this project as well as existing data from two additional, separately funded projects: the US DOE funded Illinois Basin – Decatur Project (IBDP) being conducted by the Midwest Geological Sequestration Consortium (MGSC) in Macon County, Illinois, and the Illinois Industrial Carbon Capture and Sequestration (ICCS) Project funded through the American Recovery and Reinvestment Act (ARRA), which received a phase two award from DOE. This study addresses the question of whether or not the St. Peter Sandstone may serve as a suitable target for CO2 sequestration at locations within the Illinois Basin where it lies at greater depths (below the underground source of drinking water (USDW)) than at the IBDP site. The work performed included numerous improvements to the existing St. Peter reservoir model created in 2010. Model size and spatial resolution were increased resulting in a 3 fold increase in the number of model cells. Seismic data was utilized to inform spatial porosity distribution and an extensive core database was used to develop porosity-permeability relationships. The analysis involved a Base Model representative of the St. Peter at “in-situ” conditions, followed by the creation of two hypothetical models at in-situ + 1,000 feet (ft.) (300 m) and in-situ + 2,000 ft. (600 m) depths through systematic depthdependent adjustment of the Base Model

  15. [Von Willebrand disease in the Netherlands: the WiN study].

    PubMed

    Sanders, Yvonne V; de Wee, Eva M; Meijer, Karina; Eikenboom, J; van der Bom, Jeroen G; Fijnvandraat, C J Karin; Laros-van Gorkom, Britta A P; Cnossen, Marjon H; Mauser-Bunschoten, Evelien P; Leebeek, Frank W G

    2014-01-01

    Von Willebrand disease is the most common inherited bleeding disorder and is characterised by mucocutaneous bleeding. Von Willebrand disease is caused by reduced levels or reduced function of von Willebrand factor. Depending on the cause, von Willebrand disease is distinguished into various types with their own characteristics and treatment options. The frequency and severity of bleeding in patients with von Willebrand disease is strongly determined by von Willebrand factor levels, factor VIII levels and the type of von Willebrand disease. Eighty-five percent of all adult females with von Willebrand disease reports menorrhagia. A high percentage have postpartum excessive blood loss (37% of all deliveries). The quality of life is reduced in patients with von Willebrand disease. Patients with von Willebrand disease have a reduced risk of arterial thrombosis such as a myocardial or cerebral infarction.

  16. Quantenphysik Interferometrie von C70-Molekülen

    NASA Astrophysics Data System (ADS)

    Ziegler, Thomas

    2002-05-01

    Interferenzversuche mit Neutronen und schweren Atomen stellen kein großes Problem mehr dar, selbst die Welleneigenschaften von C60-und C70-Molekülen wurden bereits nachgewiesen. Allerdings stößt man bei der Realisation immer feinerer Gitter mit Gitterkonstanten von etwa 100 nm im Fall dieser Moleküle auf technische Probleme. Wissenschaftlern der Universität Wien ist es jüngst gelungen, ein so genanntes Talbot-Lau-Interferometer zu realisieren und die Welleneigenschaften von C70 mit einer bislang unerreichten Qualität nachzuweisen [1].

  17. Valence bond and von Neumann entanglement entropy in Heisenberg ladders.

    PubMed

    Kallin, Ann B; González, Iván; Hastings, Matthew B; Melko, Roger G

    2009-09-11

    We present a direct comparison of the recently proposed valence bond entanglement entropy and the von Neumann entanglement entropy on spin-1/2 Heisenberg systems using quantum Monte Carlo and density-matrix renormalization group simulations. For one-dimensional chains we show that the valence bond entropy can be either less or greater than the von Neumann entropy; hence, it cannot provide a bound on the latter. On ladder geometries, simulations with up to seven legs are sufficient to indicate that the von Neumann entropy in two dimensions obeys an area law, even though the valence bond entanglement entropy has a multiplicative logarithmic correction.

  18. A von Bertalanffy growth model with a seasonally varying coefficient

    USGS Publications Warehouse

    Cloern, James E.; Nichols, Frederic H.

    1978-01-01

    The von Bertalanffy model of body growth is inappropriate for organisms whose growth is restricted to a seasonal period because it assumes that growth rate is invariant with time. Incorporation of a time-varying coefficient significantly improves the capability of the von Bertalanffy equation to describe changing body size of both the bivalve mollusc Macoma balthicain San Francisco Bay and the flathead sole, Hippoglossoides elassodon, in Washington state. This simple modification of the von Bertalanffy model should offer improved predictions of body growth for a variety of other aquatic animals.

  19. Alexander von Humboldt and the concept of animal electricity.

    PubMed

    Kettenmann, H

    1997-06-01

    More than two hundred years ago, Alexander von Humboldt helped to establish Galvani's view that muscle and nerve tissue are electrically excitable. His 1797 publication was a landmark for establishing the concept of animal electricity. Almost half a century later, von Humboldt became the mentor of the young du Bois-Reymond. With the help of von Humboldt's promotion, du Bois-Reymond demonstrated convincingly that animal tissue has the intrinsic capacity to generate electrical activity, and thus laid the ground for modern electrophysiology.

  20. Johann Philipp von Wurzelbau (1651-1725)

    NASA Astrophysics Data System (ADS)

    Gaab, Hans

    During the turn of the 17th to the 18th century, Johann Philipp von Wurzelbau was the best-known astronomer in Nuremberg. He was a trained merchant, who busied himself in his free hours with astronomy. In the 1680s he became known for his accurate observations of lunar and solar eclipses. At the end of the 1680s he left his trade, and from 1691, he was completely occupied with astronomy. To that end, he constructed a small octagonal observing tower on the roof of his house at Spitzenberg 4. He took the measurement of the solar path and determined the geographical coordinates of Nuremberg. The calendar reform also played a major role in his life.

  1. Hermann von Helmholtz and his students

    NASA Astrophysics Data System (ADS)

    Mulligan, Joseph F.

    1989-01-01

    During the years 1871-1888, when Hermann von Helmholtz was professor of physics at the University of Berlin, physicists from all over the world flocked to Berlin to study and do research with him. Among these were the German physicists Max Planck, Heinrich Kayser, Eugen Goldstein, Wilhelm Wien, and Heinrich Hertz, and Americans Henry Rowland, A. A. Michelson, and Michael Pupin. Examples of Helmholtz's scientific and personal interactions with these students and research associates show why he is justly considered the outstanding physics mentor of the 19th century. Both his ideas and his students played a major role in the development of physics in the late 19th and early 20th centuries.

  2. Leichte Neucodierung von Selenocystein in der Natur

    PubMed Central

    Mukai, Takahito; Englert, Markus; Tripp, H. James; Miller, Corwin; Ivanova, Natalia N.; Rubin, Edward M.; Kyrpides, Nikos C.

    2016-01-01

    Selenocystein (Sec oder U) wird durch Neuzuordnung des Stopp-Codons UGA durch einen Sec-spezifischen Elongationsfaktor und eine charakteristische RNA-Struktur codiert. Um mögliche Codonvariationen zu finden, analysierten wir 6.4 Billionen Basenpaare metagenomischer Daten sowie 24903 mikrobielle Genome für tRNASec-Spezies. UGA ist erwartungsgemäβ das vorherrschende Codon für Sec, allerdings finden wir auch tRNASec-Spezies, die die Stopp-Codons UAG und UAA erkennen, sowie weitere zehn Sense-Codons. Die Synthese von Selenoproteinen durch UAG in Geodermatophilus und Blastococcus sowie durch das Cys-Codon UGA in Aeromonas salmonicida konnte durch metabolische Markierung mit 75Se oder Massenspektrometrie bestätigt werden. Weitere tRNASec-Spezies mit verschiedenen Anticodons ermöglichten es Escherichia coli, die aktive Form des Selenoproteins Formiatdehydrogenase H zu synthetisieren. Der genetische Code ist damit bedeutend flexibler, als bisher angenommen. PMID:27440945

  3. Von Economo neurons in the elephant brain.

    PubMed

    Hakeem, Atiya Y; Sherwood, Chet C; Bonar, Christopher J; Butti, Camilla; Hof, Patrick R; Allman, John M

    2009-02-01

    Von Economo neurons (VENs), previously found in humans, all of the great ape species, and four cetacean species, are also present in African and Indian elephants. The VENs in the elephant are primarily found in similar locations to those in the other species. They are most abundant in the frontoinsular cortex (area FI) and are also present at lower density in the anterior cingulate cortex. Additionally, they are found in a dorsolateral prefrontal area and less abundantly in the region of the frontal pole. The VEN morphology appears to have arisen independently in hominids, cetaceans, and elephants, and may reflect a specialization for the rapid transmission of crucial social information in very large brains.

  4. Johann von Lamont: A Pioneer in Geomagnetism

    NASA Astrophysics Data System (ADS)

    Soffel, Heinrich

    2006-06-01

    The 200th birthday of John Lamont (1805-1879, Figure 1), a pioneer in the study of geomagnetism, was marked on 13 December 2005. Lamont founded the Munich Geomagnetic Observatory in 1840 and was a member of the group of scientists including Carl Friedrich Gauss, Alexander von Humboldt, Eduard Sabine, Jonas Angstrøm, Humphret Lloyd, Adolf Kupffer, Karl Kreil, and Adolphe Quetelet who composed the Göttingen Magnetic Union. They organized an international network of geomagnetic observatories [Barraclough et al., 1992]. The present knowledge of the geomagnetic field and its secular variation is largely based on the data collected by the global network of geomagnetic observatories during the last 170 years. Lamont's talents and his dedication and enthusiasm for discovery are reflected in the depth and scope of his contributions to a broad variety of natural sciences such as astronomy, meteorology, geomagnetism, and geodesy. However, this article just touches on his merits in geomagnetism.

  5. HL-10 on lakebed with Jerauld R. Gentry, Peter Hoag, John A. Manke, and Bill Dana

    NASA Technical Reports Server (NTRS)

    1969-01-01

    The four principal HL-10 pilots are seen here with the lifting body aircraft. They are, left to right; Air Force Major Jerauld R. Gentry, Air Force test pilot Peter Hoag, and NASA pilots John A. Manke and Bill Dana. All are wearing the pressure suits needed for flying above 50,000 feet. The HL-10 was one of five heavyweight lifting-body designs flown at NASA's Flight Research Center (FRC--later Dryden Flight Research Center), Edwards, California, from July 1966 to November 1975 to study and validate the concept of safely maneuvering and landing a low lift-over-drag vehicle designed for reentry from space. Northrop Corporation built the HL-10 and M2-F2, the first two of the fleet of 'heavy' lifting bodies flown by the NASA Flight Research Center. The contract for construction of the HL-10 and the M2-F2 was $1.8 million. 'HL' stands for horizontal landing, and '10' refers to the tenth design studied by engineers at NASA's Langley Research Center, Hampton, Va. After delivery to NASA in January 1966, the HL-10 made its first flight on Dec. 22, 1966, with research pilot Bruce Peterson in the cockpit. Although an XLR-11 rocket engine was installed in the vehicle, the first 11 drop flights from the B-52 launch aircraft were powerless glide flights to assess handling qualities, stability, and control. In the end, the HL-10 was judged to be the best handling of the three original heavy-weight lifting bodies (M2-F2/F3, HL-10, X-24A). The HL-10 was flown 37 times during the lifting body research program and logged the highest altitude and fastest speed in the Lifting Body program. On Feb. 18, 1970, Air Force test pilot Peter Hoag piloted the HL-10 to Mach 1.86 (1,228 mph). Nine days later, NASA pilot Bill Dana flew the vehicle to 90,030 feet, which became the highest altitude reached in the program. Some new and different lessons were learned through the successful flight testing of the HL-10. These lessons, when combined with information from it's sister ship, the M2-F2/F3

  6. Peter Andreas Hansen and the astronomical community - a first investigation of the Hansen papers. (German Title: Peter Andreas Hansen und die astronomische Gemeinschaft - eine erste Auswertung des Hansen-Nachlasses. )

    NASA Astrophysics Data System (ADS)

    Schwarz, Oliver; Strumpf, Manfred

    The literary assets of Peter Andreas Hansen are deposited in the Staatsarchiv Hamburg, the Forschungs- und Landesbibliothek Gotha and the Thüringer Staatsarchiv Gotha. They were never systematically investigated. We present here some results of a first evaluation. It was possible to reconstruct the historical events with regard to the maintenance of the Astronomische Nachrichten and the Altona observatory in 1854. Hansen was a successful teacher for many young astronomers. His way of stimulating the evolution of astronomy followed Zach's tradition.

  7. 7. Historic American Buildings Survey, Charles Von Urban, Photographer June ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Historic American Buildings Survey, Charles Von Urban, Photographer June 23, 1936, INTERIOR-PARLOR SHOWING FIREPLACE, WINDOWN TRIM, AND CORNICE. - George Fordham House, 329 Cherry Street, New York County, NY

  8. Fletcher and von Braun at Apollo 15 launch

    NASA Technical Reports Server (NTRS)

    1971-01-01

    Recently appointed NASA Administrator Dr. James C. Fletcher, left, and Dr. Wernher von Braun, Deputy Associate Administrator for Planning, monitor Apollo 15 prelaunch activities in Firing Room 1 of the Launch Control Center and the Kennedy Space Center, Florida.

  9. Dr. von Braun at the Manufacturing and Engineering Laboratory

    NASA Technical Reports Server (NTRS)

    1967-01-01

    Dr. von Braun, Director of the Marshall Space Flight Center, listens attentively to a briefing on the metal forming techniques by Dr. Mathias Siebel of the Manufacturing and Engineering Laboratory at MSFC on October 17, 1967.

  10. 33. HISTORIC VIEW OF WERNHER VON BRAUN LOOKS THROUGH THE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    33. HISTORIC VIEW OF WERNHER VON BRAUN LOOKS THROUGH THE PERISCOPE FROM THE CONTROL ROOM AT TEST STAND NO. 1, PEENEMUENDE. - Marshall Space Flight Center, Redstone Rocket (Missile) Test Stand, Dodd Road, Huntsville, Madison County, AL

  11. Dr. Wernher Von Braun examines a ruby crystal.

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. Wernher Von Braun (right), director of the Marshall Space Flight Center, and Dr. Eberhard Rees (left), deputy director, technical, examine a ruby crystal used in laser experiments in the Marshall Center's Space Sciences Laboratory.

  12. A proof of von Neumann's postulate in Quantum Mechanics

    SciTech Connect

    Conte, Elio

    2010-05-04

    A Clifford algebraic analysis is explained. It gives proof of von Neumann's postulate on quantum measurement. It is of basic significance to explain the problem of quantum wave function reduction in quantum mechanics.

  13. Alexander von Humboldt and the Origins of Landscape Archaeology.

    ERIC Educational Resources Information Center

    Mathewson, Kent

    1986-01-01

    Reviews the life, theories, and influence of Alexander von Humboldt, the early nineteenth century founder of modern geography. Maintains that Humboldt's novel approaches to the study of landscape antiquities have value for contemporary students in cultural and historical geography. (JDH)

  14. Can a Quantum Computer Run the von Neumann Architecture?

    NASA Astrophysics Data System (ADS)

    Hines, P.

    At the core of nearly every modern computer is a central processing unit running the von Neumann architecture. This computer architecture gives computationally universal machines, and non-trivial control structures arise naturally, leading to high-level programming constructs.

  15. Physik gestern und heute Von der Metallstange zum Hochenergielaser

    NASA Astrophysics Data System (ADS)

    Heering, Peter

    2002-05-01

    Im Mai 1752 wurde in Marly bei Paris auf Anregung des amerikanischen Forschers und Politikers Benjamin Franklin erstmals die elektrische Natur des Blitzes nachgewiesen. Damals beschrieb Franklin auch eine technische Vorrichtung, die als Schutz von Gebäuden vor Blitzschlägen dienen sollte: den Blitzableiter. Diese aus heutiger Sicht scheinbar triviale Vorrichtung wurde aber keineswegs unmittelbar akzeptiert. Und bis heute ist die Forschung zum Schutz von Einrichtungen vor Blitzschlägen nicht abgeschlossen.

  16. Gastrointestinal angiodysplasia and bleeding in von Willebrand disease.

    PubMed

    Franchini, M; Mannucci, P M

    2014-09-02

    Von Willebrand disease (VWD), the most common genetic bleeding disorder, is characterised by a quantitative or qualitative defect of von Willebrand factor (VWF). Patients with VWD suffer from mucocutaneous bleeding, of severity usually proportional to the degree of VWF defect. In particular, gastrointestinal bleeding associated with angiodysplasia is often a severe symptom of difficult management. This review focuses on the pathophysiology, diagnosis and treatment of VWD-associated gastrointestinal angiodysplasia and related bleeding.

  17. Wernher von Braun with German Officers and Others

    NASA Technical Reports Server (NTRS)

    1942-01-01

    General Erich Fellgiebel, head of the German Army Information Service during World War II, congratulates members of the von Braun rocket team from Peenemunde for their October 3, 1942 A4 flight. Pictured front center is General Erich Fellgiebel. Shaking hands are General Walter Dornberger (left) and General Janssen, commanding officer of Peenemuende with Rudolph Hermarn to their right. Picture left to right in the back row are Wernher von Braun, Captain Stoelzel, Luftwaffe, and Dr. Gerhard Reisig.

  18. Psychometric properties of Peters et al. delusions inventory-21 in adolescence.

    PubMed

    Kim, Yeni; Chang, Jae Seung; Hwang, Samuel; Yi, Jung Seo; Cho, In Hee; Jung, Hee Yeon

    2013-05-30

    We explored the psychometric properties of the Korean version of the Peters et al. delusions inventory-21 (PDI-21) and evaluated the item characteristics of the PDI-21 compared with the Magical Ideation Scale (MIS) in Korean community adolescents. Survey participants comprised 310 Year 10 students who were assessed with the following instruments: the PDI-21, the MIS, the Schizotypal Personality Scale (STA) and the symptom checklist-90-R (SCL-90-R). The item characteristics of the PDI-21 and MIS were also explored using item response theory (IRT). The PDI-21 exhibited good internal consistency and demonstrated significant correlations with the MIS, STA and all subscale scores of the SCL-90-R, indicating psychological distress in adolescents with high PDI-21 scores. We also found through IRT analysis that the PDI-21 provides more information at the lower range and the MIS at the higher range of delusion proneness. Our findings suggest that the PDI-21 is an effective and reliable self-report measure for assessment of delusion proneness and that the PDI-21 and the MIS may be used complementarily to assess a broad range of delusion proneness among community adolescents. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  19. Taxonomic corrections to species of Rhyparochromidae (Hemiptera: Heteroptera) described by Carl Peter Thunberg.

    PubMed

    Kondorosy, Előd; Rédei, Dávid; Mejlon, Hans

    2014-07-22

    Types of Rhyparochromidae (Hemiptera: Heteroptera: Lygaeoidea) species described by Carl Peter Thunberg, deposited in the Museum of Evolution (formerly Zoologiska Institut), Uppsala University, Uppsala, Sweden, were reexamined and the taxonomic and nomenclatural problems that existed among those species discussed and resolved as required. Lectotypes are designated for Cimex caffer Thunberg, 1784, Lygaeus ater Thunberg, 1822, Lygaeus biguttatus Thunberg, 1822, and Pendulinus guttatus Thunberg, 1825. The lectotype of Pendulinus (now Metochus) guttatus is designated as neotype of Pendulinus (now Metochus) uniguttatus Thunberg, 1822; as a result the former name becomes junior objective synonym of the latter. The following taxonomic changes are proposed: Lethaeus ater (Thunberg, 1822), new combination (from Lygaeus); Migdilybs biguttatus (Thunberg, 1822), new combination (from Lygaeus) = Migdilybs furcifer Hesse, 1925, new subjective synonym; Metochus uniguttatus (Thunberg, 1822) = Metochus bengalensis (Dallas, 1852), confirmed subjective synonym = Metochus yeh (Dohrn, 1860), confirmed subjective synonym; Raglius alboacuminatus (Goeze, 1778) = Cimex caffer Thunberg, 1874, confirmed subjective synonym. Lethaeus barberi Slater, 1964 does not belong to Lethaeus Dallas, 1852 but currently it cannot be placed with confidence in any existing genus. 

  20. Controlled infection of Poecilia reticulata Peters (guppy) with Tetrahymena by immersion and intraperitoneal injection.

    PubMed

    Sharon, G; Pimenta-Leibowitz, M; Vilchis, M C L; Isakov, N; Zilberg, D

    2015-01-01

    Tetrahymena is a protozoan parasite, which infects guppy, Poecilia reticulata Peters, and causes substantial economical losses in commercial farms worldwide. Studies of guppy infected by Tetrahymena require standardized infection protocols. The LD50 for Tetrahymena infection of guppies by intraperitoneal (IP) injection was calibrated, and the level obtained was 946 parasites per fish. Guppy infection with Tetrahymena by immersion, imitating the natural route of infection via the integument, was studied under normal or stress conditions. Exposure to cold and netting (CNI) and to cold only (CI) followed by immersion exposure to 10 000 Tetrahymena per mL resulted in 22.5% and 19.2% mortality, respectively, as compared to 14.2% and 10% in groups that were netted only (NI) or non-stressed (I). Histopathology revealed that immersion infection resulted in a systemic infection. Lysozyme levels, measured 3 weeks after infection, were significantly higher in the CNI group (288 μg per mg protein) compared with CI-, NI- and I-treated groups (94.5, 64 and 62.3 μg mg(-1), respectively). There was no evident parasite immobilization activity in body homogenates, suggesting no development of acquired immunity. Re-infection by IP injection revealed no increase in protection in any of the treatment groups, mortality range of 56.3-75%, higher than in the non-exposed control (40.6% mortality). © 2014 John Wiley & Sons Ltd.

  1. Newly found sunspot observations by Peter Becker from Rostock for 1708, 1709, and 1710

    NASA Astrophysics Data System (ADS)

    Neuhäuser , R.; Arlt, R.; Pfitzner, E.; Richter, S.

    2015-09-01

    We present a few newly found old sunspot observations from the years AD 1708, 1709, and 1710, which were obtained by Peter Becker from Rostock, Germany. For 1709, Becker gave a detailed drawing: he observed a sunspot group made up of two spots on January 5, 6, and 7, and just one of the two spots was observed on January 8 and 9. We present his drawing and his explanatory text. We can measure the latitude and longitude of these two spots and estimate their sizes for all five days. While the spots and groups in 1708 and the spot on four of the five days in January 1709 were known before from other observers (e.g. Hoyt & Schatten 1998), the location of the spots in early January 1709 were not known before, so that they can now be considered in reconstructed butterfly diagrams. The sunspots detected by Becker on 1709 January 5 and 1710 September 10 were not known before at all, as the only observer known for those two dates, La Hire, did not detect that spot (group). We estimate new group sunspot numbers for the relevant days, months, and years. The time around 1708-1710 is important, because it documents the recovery of solar activity towards the end of the Maunder Grand Minimum. We also show two new spot observations from G. Kirch for 1708 September 13 and 14 as described in his letter to Wurzelbaur (dated Berlin AD 1708 December 19).

  2. Pescadillo homologue 1 and Peter Pan function during Xenopus laevis pronephros development.

    PubMed

    Tecza, Aleksandra; Bugner, Verena; Kühl, Michael; Kühl, Susanne J

    2011-10-01

    pes1 (pescadillo homologue 1) and ppan (Peter Pan) are multifunctional proteins involved in ribosome biogenesis, cell proliferation, apoptosis, cell migration and regulation of gene expression. Both proteins are required for early neural development in Xenopus laevis, as previously demonstrated. We show that the expression of both genes in the developing pronephros depends on wnt4 and fzd3 (frizzled homologue 3) function. Loss of pes1 or ppan by MO (morpholino oligonucleotide)-based knockdown approaches resulted in strong malformations during pronephric tubule formation. Defects were already notable during specification of pronephric progenitor cells, as shown by lhx1 expression. Moreover, we demonstrated that Xenopus pes1 and ppan interact physically and functionally and that pes1 and ppan can cross-rescue the loss of function phenotype of one another. Interference with rRNA synthesis, however, did not result in a similar early pronephros phenotype. These results demonstrate that pes1 and ppan are required for Xenopus pronephros development and indicate that their function in the pronephros is independent of their role in ribosome biosynthesis.

  3. Cloning and characterization of peter pan, a novel Drosophila gene required for larval growth.

    PubMed

    Migeon, J C; Garfinkel, M S; Edgar, B A

    1999-06-01

    We identified a new Drosophila gene, peter pan (ppan), in a screen for larval growth-defective mutants. ppan mutant larvae do not grow and show minimal DNA replication but can survive until well after their heterozygotic siblings have pupariated. We cloned the ppan gene by P-element plasmid rescue. ppan belongs to a highly conserved gene family that includes Saccharomyces cerevisiae SSF1 and SSF2, as well as Schizosaccharomyces pombe, Arabidopsis, Caenorhabditis elegans, mouse, and human homologues. Deletion of both SSF1 and SSF2 in yeast is lethal, and depletion of the gene products causes cell division arrest. Mosaic analysis of ppan mutant clones in Drosophila imaginal disks and ovaries demonstrates that ppan is cell autonomous and required for normal mitotic growth but is not absolutely required for general biosynthesis or DNA replication. Overexpression of the wild-type gene causes cell death and disrupts the normal development of adult structures. The ppan gene family appears to have an essential and evolutionarily conserved role in cell growth.

  4. Principles of plastic surgery portrayed by the professional life of Dr John Peter Mettauer.

    PubMed

    Avashia, Yash J; Thaller, Seth R

    2011-11-01

    Regarded as "America's first plastic surgeon," Dr John Peter Mettauer's professional life displays 3 fundamental keystones of plastic surgery: education, innovation, and practice. To fully appreciate the history of our plastic surgery, one must look beyond a purely factual recount of noteworthy actions performed decades ago. Fundamental principles that governed achievements of our predecessors remain applicable even today. Dr Mettauer thrived as a medical student under the influence of distinguished professors in medicine at the University of Pennsylvania. Later, he continued to propagate their basic tenets when he established his medical institute in 1837. Throughout his life, Dr Mettauer combined ingenuity with scientific inquiry to devise numerous unprecedented surgical techniques and instruments. He was a prolific writer and exquisitely documented his work in medical journals for the benefit of both contemporary and future surgeons. One of Dr Mettauer's momentous achievements in plastic surgery that displays his remarkable capabilities was his contributions to management of both simple and complicated cases of cleft palate. He was the first to describe relaxing lateral incisions for treating complete cleft palates and, incidentally, was the first to successfully treat this in America. He invariably replicated similar success in establishing techniques for treating a wide range of anatomic deformities. Cumulatively, Dr Mettauer's lifelong commitment and diligence have truly laid a foundation for the eventual progress and success in the field of plastic surgery.

  5. Slope Convection in the Peter the Great Bay and Ventilation of the Japan Sea

    NASA Astrophysics Data System (ADS)

    Lobanov, V. B.; Sergeev, A.; Gorin, I.; Scherbinin, P.; Voronin, A.; Kaplunenko, D.; Gulenko, T.

    2016-02-01

    Cascading of dense shelf water along the slope (slope convection) of Peter the Great Bay in the northwestern Japan Sea in winter is one of the key mechanisms of ventilation of the Japan Sea deep layers. Results of direct observations of cascading by autonomous mooring systems and repeated CTD surveys during winters of 2012-2014 have been presented here. The events of dense water, formed by cooling and brine rejection on the shelf during ice formation, approaches the shelf edge (100 m) have been registered every winter usually in February - March. However their duration has been varied interannually reflecting climatic changes. Only one episode of deep down slope cascading was registered by mooring at 1150 m. Its duration was only around 12 hours. These very transient events however resulted in a number of intrusions of colder, less saline, higher oxygen content and higher turbidity water detected by CTD casts observed down to 2000-2800 m indicating penetration of cascading down to the bottom of the slope and thus ventilation of the intermediate, deep and bottom waters of the Japan Sea. Depending on a severity of winter the intrusions formed by cascading water ventilate intermediate layers (winters of 2013-2014) or may penetrate down to the bottom layer (extremely cold winter 2001). In any case this ventilation mechanism is important to understand water mass transformation in the Japan Sea.

  6. Transmission of white spot syndrome virus (WSSV) from Dendronereis spp. (Peters) (Nereididae) to penaeid shrimp.

    PubMed

    Haryadi, D; Verreth, J A J; Verdegem, M C J; Vlak, J M

    2015-05-01

    Dendronereis spp. (Peters) (Nereididae) is a common polychaete in shrimp ponds built on intertidal land and is natural food for shrimp in traditionally managed ponds in Indonesia. White spot syndrome virus (WSSV), an important viral pathogen of the shrimp, can replicate in this polychaete (Desrina et al. 2013); therefore, it is a potential propagative vector for virus transmission. The major aim of this study was to determine whether WSSV can be transmitted from naturally infected Dendronereis spp. to specific pathogen-free (SPF) Pacific white shrimp Litopenaeus vannamei (Boone) through feeding. WSSV was detected in naturally infected Dendronereis spp. and Penaeus monodon Fabricius from a traditional shrimp pond, and the positive animals were used in the current experiment. WSSV-infected Dendronereis spp. and P. monodon in a pond had a point prevalence of 90% and 80%, respectively, as measured by PCR. WSSV was detected in the head, gills, blood and mid-body of Dendronereis spp. WSSV from naturally infected Dendronereis spp was transmitted to SPF L. vannamei and subsequently from this shrimp to new naïve-SPF L. vannamei to cause transient infection. Our findings support the contention that Dendronereis spp, upon feeding, can be a source of WSSV infection of shrimp in ponds. © 2014 John Wiley & Sons Ltd.

  7. Acute toxic effects of fenpyroximate acaricide on Guppy (Poecilia reticulata Peters, 1859).

    PubMed

    Doğan, Nesli; Yazıcı, Zehra; Şişman, Turgay; Aşkin, Hakan

    2013-09-01

    Fenpyroximate (FP), an acaricide, is widely used in the prevention of acarids (mites) in fruit plant gardens. In this study, the acute toxic effects of different concentrations of FP were investigated using adult guppy (Poecilia reticulata Peters, 1859). Guppy adults were exposed to a range of FP concentrations (25, 50, 75, 100, 125, and 150 µg/L) during 48 h. Static method, which is one of the acute toxicity experiments, has been used in this study. According to probit analysis, the 48-h median lethal concentration (LC50) value of FP at 26°C was found to be 72.821 µg/L. Sublethal exposures were predetermined based on 48-h LC50 value. Guppies were exposed to low concentrations (15, 25, and 50 µg/L) of FP for 48 h. Signs of paralysis and behavior deformations were monitored every 12 h in a number of live and dead adults. Low concentrations of FP were also responsible for erratic swimming, loss of equilibrium, and being lethargic. Liver histology revealed several pathological damages including congestion, picnotic nucleus, sinusoidal dilatation, increase in melanomacrophagic centers, and endothelial degeneration. Finally, the toxicity test results provided 48-h LC50 value for FP, and low concentrations of FP can be highly detrimental to guppy adults with clear evidence of behavioral and histologic effects.

  8. "Pop" psychoanalysis, kitsch, and the "as if" theater: further notes on Peter Shaffer's Equus.

    PubMed

    Gifford, S

    1976-01-01

    This paper is intended as an examination of Dr. Stamm's (1975) paper and of Dr. Jules Glenn's discussion of Peter Shaffer's previous work. Its premise is the futility of subjecting Equus to a traditional psychoanalytic investigation, as a product of the playwright's unconscious, when the play represents a skillful, highly conscious use of analytic cliches to manipulate the audience. This phenomenon, however, and the play's great popularity prompt some reflections on the nature of kitsch, or false art, and its differences from authentic drama. The experience of kitsch can be identified when the spectator feels coerced by exaggerated, unconvincing theatrical devices, and fails to experience genuine empathy with the characters in a play. In the experience of authentic tragedy there is some element of voluntary surrender, of suspension of disbelief with full consent of will, as in the Aristotelian concept of catharsis. Shaffer's play is discussed as an illustration of this distinction and its relation to pseudoemotionality, the impostor syndrome, and the "as if" personality. In conclusion, the play's failure to evoke a genuine emotional response is explained by interpreting Equus as an "as if" tragedy.

  9. Emotional Mental Imagery as Simulation of Reality: Fear and Beyond-A Tribute to Peter Lang.

    PubMed

    Ji, Julie L; Heyes, Stephanie Burnett; MacLeod, Colin; Holmes, Emily A

    2016-09-01

    This article pays tribute to the seminal paper by Peter J. Lang (1977; this journal), "Imagery in Therapy: Information Processing Analysis of Fear." We review research and clinical practice developments in the past five decades with reference to key insights from Lang's theory and experimental work on emotional mental imagery. First, we summarize and recontextualize Lang's bio-informational theory of emotional mental imagery (1977, 1979) within contemporary theoretical developments on the function of mental imagery. Second, Lang's proposal that mental imagery can evoke emotional responses is evaluated by reviewing empirical evidence that mental imagery has a powerful impact on negative as well as positive emotions at neurophysiological and subjective levels. Third, we review contemporary cognitive and behavioral therapeutic practices that use mental imagery, and consider points of extension and departure from Lang's original investigation of mental imagery in fear-extinction behavior change. Fourth, Lang's experimental work on emotional imagery is revisited in light of contemporary research on emotional psychopathology-linked individual differences in mental imagery. Finally, key insights from Lang's experiments on training emotional response during imagery are discussed in relation to how specific techniques may be harnessed to enhance adaptive emotional mental imagery training in future research.

  10. Controls on deposition of the St. Peter Sandstone (Middle-Late Ordovician), Michigan basin

    SciTech Connect

    Nadon, G.C.; Simo, A.; Byers, C.W.; Dott, R.H, Jr. )

    1991-08-01

    The St. Peter Sandstone (Middle-late Ordovician) of the Michigan basin represents an approximately 10-m.y. interval of clastic deposition in an otherwise carbonate-dominated Ordovician succession. This interval, up to 320 m thick, also coincides with a change in basin configuration from the nearly circular depocenter of the underlying Shakopee Formation to an east-west elongate trough situated west to Saginaw Bay. Interpretation of well logs and core from throughout the basin indicates that the clastics are composed of 20-25 sequences upper shoreface to tidal-flat environments. The sequences are interbedded with heavily bioturbated, shaly, lower shoreface sandstones (1-14 m thick) and, in the central and southeastern parts of the basin, with carbonate shales, stromatolites, and oolitic grain-stones (2-39 m thick). The eastern and southeastern margins of the basin contain the thickest carbonate accumulations. Hydrocarbons fields are located over structural highs formed by reactivation of basement structures. Detailed comparison of well logs within field shows that sedimentary cycles thin over the structures as a result of the local reduction in the formation of accommodation space by syndepositional movements on the faults. The presence of thick carbonates along the southeastern margin of the basin is a result of the combination of distance form the clastic source and the episodic formation of accommodation space by syndepositional normal faulting along the basin margin.

  11. Hydrogeology for land-use planning: the Peters Creek area, Municipality of Anchorage, Alaska

    USGS Publications Warehouse

    Brunett, Jilann O.; Lee, Michael

    1983-01-01

    Wells currently provide all water supplies in the area. Most wells obtain enough water for individual household needs from unconsolidated, principally glacial and glacioalluvial deposits. In some places, however, wells must be drilled into the underlying bedrock to obtain adequate supplies. It may be possible to develop small community supplies--for individual trailer courts or subdivisions--in areas where yields of 20 gallons per minute or greater are reported for private, domestic wells. Peters Creek is a potential source of surface-water supply, but it would have to be treated to remove glacial silt during summer months. The chemical quality of both ground water and surface water in the area in generally acceptable for most uses. Foundation and excavation conditions, the potential for water pollution from onsite disposal of wastewater through septic tank systems, and the suitability of specific areas for certain types of development may be affected by the following factors: wetlands and areas of shallow ground water underlie about 30 percent of the study area; landslope exceeds 20 percent in about a third of the area; areas of fine-grained, low-permeability sediments are present locally; bedrock is within 25 feet of the land surface in about a third of the area. (USGS)

  12. The Sunspot Catalogues of Carrington, Peters and de la Rue: Quality Control and Machine-Readable Versions

    NASA Astrophysics Data System (ADS)

    Casas, R.; Vaquero, J. M.

    2014-01-01

    In the 19th century, several astronomers made observations of sunspots, recording their positions and sometimes their areas. These observations were published in the form of extensive tables, but have been unhelpful until now. Three of these observers were Richard C. Carrington, Christian H.F. Peters and Warren de la Rue (and their respective collaborators). They published, in various articles, the data corresponding to 26 641 sunspot positions (Carrington, Peters and de la Rue registered 4900, 14040 and 7701 sunspot positions, respectively). In this paper we present a translation of more than 400 pages of their printed numerical tables into a machine readable format, including an initial analysis targeted at detecting possible mistakes in the reading or in the original transcription. The observations carried out by these three astronomers have been made available at the Centre de Donées Astronomiques de Strasbourg (http://cdsarc.u-strasbg.fr/cgi-bin/VizieR?-source=VI/138).

  13. Management of Type 2B von Willebrand Disease during Pregnancy.

    PubMed

    McLaughlin, David; Kerr, Ron

    2017-01-01

    Type 2B von Willebrand disease is a rare bleeding condition resulting in thrombocytopenia and a reduction in large VWF multimers. It usually has an autosomal dominant pattern of inheritance. We report the management of a patient with type 2B von Willebrand disease, whose diagnosis was confirmed by demonstration of a R1306W mutation, through her first pregnancy. The patient's von Willebrand factor (VWF) antigen and VWF ristocetin cofactor levels rose throughout pregnancy, with an associated drop in the platelet count. The patient was successfully managed through labour to a surgical delivery with VWF concentrate, platelet transfusions and tranexamic acid. The patient delivered a male baby who was found to have inherited type 2B von Willebrand disease and had a significant cephalhaematoma at delivery. The baby was managed with VWF concentrate and platelet transfusions and made a full recovery. There is a lack of evidence to guide the best management of pregnant patients with type 2B von Willebrand disease. We adopted a pragmatic management plan, in keeping with other published case reports. To the best of our knowledge, this is the first case report in which the child was found to have inherited type 2B von Willebrand disease and encountered bleeding problems, making this case unique amongst the published literature.

  14. Wildlife and Wildlife Habitat Loss Assessment at Green Peter-Foster Project; Middle Fork Santiam River, Oregon, 1985 Final Report.

    SciTech Connect

    Noyes, J.H.

    1986-02-01

    A habitat based assessment was conducted of the US Army Corps of Engineers' Green Peter-Foster Dam and Reservoir Project on the Middle Fork Santiam River, Oregon, to determine losses or gains resulting from the development and operation of the hydroelectric related components of the project. Preconstruction, postconstruction, and recent vegetation cover types at the project site were mapped based on aerial photographs from 1955, 1972, and 1979, respectively. Vegetation cover types were identified within the affected area and acreages of each type at each period were determined. Eleven wildlife target species were selected to represent a cross-section of species groups affected by the project. An interagency team evaluated the suitability of the habitat to support the target species at each time period. An evaluation procedure which accounted for both the quantity and quality of habitat was used to aid in assessing impacts resulting from the project. The Green Peter-Foster Project extensively altered or affected 7873 acres of land and river in the Santiam River drainage. Impacts to wildlife centered around the loss of 1429 acres of grass-forb vegetation, 768 acres of shrubland, and 717 acres of open conifer forest cover types. Impacts resulting from the Green Peter-Foster Project included the loss of critical winter range for black-tailed deer and Roosevelt elk, and the loss of year-round habitat for deer, upland game birds, river otter, beaver, pileated woodpecker, and many other wildlife species. Bald eagle and osprey were benefited by an increase in foraging habitat. The potential of the affected area to support wildlife was greatly altered as a result of the Green Peter-Foster Project. Losses or gains in the potential of the habitat to support wildlife will exist over the life of the project.

  15. Theoretical Claims Necessitate Basic Research: Reply to Gawronski, Lebel, Peters, and Banse (2009) and Nosek and Greenwald (2009)

    ERIC Educational Resources Information Center

    De Houwer, Jan; Teige-Mocigemba, Sarah; Spruyt, Adriaan; Moors, Agnes

    2009-01-01

    The authors of this reply article note that B. Gawronski, E. P. LeBel, K. R. Peters, and R. Banse (2009) (a) expressed agreement in their comment with the analysis put forward in the target article (J. De Houwer, S. Teige-Mocigemba, A. Spruyt, & A. Moors, 2009) and (b) pointed to a further implication for the way in which the implicitness of a…

  16. Exponential Size Distribution of von Willebrand Factor

    PubMed Central

    Lippok, Svenja; Obser, Tobias; Müller, Jochen P.; Stierle, Valentin K.; Benoit, Martin; Budde, Ulrich; Schneppenheim, Reinhard; Rädler, Joachim O.

    2013-01-01

    Von Willebrand Factor (VWF) is a multimeric protein crucial for hemostasis. Under shear flow, it acts as a mechanosensor responding with a size-dependent globule-stretch transition to increasing shear rates. Here, we quantify for the first time, to our knowledge, the size distribution of recombinant VWF and VWF-eGFP using a multilateral approach that involves quantitative gel analysis, fluorescence correlation spectroscopy, and total internal reflection fluorescence microscopy. We find an exponentially decaying size distribution of multimers for recombinant VWF as well as for VWF derived from blood samples in accordance with the notion of a step-growth polymerization process during VWF biosynthesis. The distribution is solely described by the extent of polymerization, which was found to be reduced in the case of the pathologically relevant mutant VWF-IIC. The VWF-specific protease ADAMTS13 systematically shifts the VWF size distribution toward smaller sizes. This dynamic evolution is monitored using fluorescence correlation spectroscopy and compared to a computer simulation of a random cleavage process relating ADAMTS13 concentration to the degree of VWF breakdown. Quantitative assessment of VWF size distribution in terms of an exponential might prove to be useful both as a valuable biophysical characterization and as a possible disease indicator for clinical applications. PMID:24010664

  17. [Type 2N von Willebrand disease (Normandy)].

    PubMed

    Morales-De la Vega, Alejandro; Reyes-Maldonado, Elba; Martínez-Murillo, Carlos; Quintana-González, Sandra

    2008-01-01

    the results of the laboratory test for 2N von Willebrand disease (2N vWD) are indistinguishable from those of light or moderate haemophilia A, until the technique that evaluates the operation of the vWF: FVIII binding is performed. to determine the prevalence of type 2N vWD in patients diagnosed with light or moderate haemophilia A and type 1 vWD. twelve healthy donors and twenty-five patients diagnosed with haemophilia A (a carrier) and five suspected of type 1 vWD were included in the study. The common tests of haemostasis for this condition plus the technique of the relationship of the vWF: FVIII recombinant (F VIIIr) binding was performed. the laboratory results of the 30 patients were concordant with the previous diagnosis. However, three with a previous diagnosis of haemophilia A demonstrated a rate of relationship of the vWF: F VIIIr binding lower than the reference interval obtained from the healthy donors, which means it corresponds to 2N vWD. the screening method of 2N vWD employed in this study allowed to identify for first time in Mexico, the first cases of this variant with a prevalence of 10%. In our country, this method will allow to establishing accurate diagnosis of 2N vWD and to providing specific treatments.

  18. Quantum control by von Neumann measurements

    NASA Astrophysics Data System (ADS)

    Pechen, Alexander; Il'in, Nikolai; Shuang, Feng; Rabitz, Herschel

    2006-11-01

    A general scheme is presented for controlling quantum systems using evolution driven by nonselective von Neumann measurements, with or without an additional tailored electromagnetic field. As an example, a two-level quantum system controlled by nonselective quantum measurements is considered. The control goal is to find optimal system observables such that consecutive nonselective measurement of these observables transforms the system from a given initial state into a state which maximizes the expected value of a target operator (the objective). A complete analytical solution is found including explicit expressions for the optimal measured observables and for the maximal objective value given any target operator, any initial system density matrix, and any number of measurements. As an illustration, upper bounds on measurement-induced population transfer between the ground and the excited states for any number of measurements are found. The anti-Zeno effect is recovered in the limit of an infinite number of measurements. In this limit the system becomes completely controllable. The results establish the degree of control attainable by a finite number of measurements.

  19. von Willebrand factor expression in osteosarcoma metastasis.

    PubMed

    Eppert, Kolja; Wunder, Jay S; Aneliunas, Vicky; Kandel, Rita; Andrulis, Irene L

    2005-03-01

    A number of genes are implicated in the initiation and progression of osteosarcoma; however, cytogenetic and comparative genomic hybridization studies indicate the involvement of additional unidentified genes. An examination of gene expression profiles in 22 high-grade osteosarcoma tumor specimens from 15 patients (including paired primary and metastatic samples from five patients) indicated that von Willebrand factor (vWF) mRNA expression may increase during tumor progression. vWF, a large glycoprotein previously considered to be expressed exclusively by endothelial cells and megakaryocytes, is involved in platelet aggregation and adhesion to the subendothelial matrix, processes critical to hematogenous tumor cell metastasis to the lung. Analysis of paired primary and metastatic osteosarcoma tumor samples from 10 patients revealed an increase in vWF gene expression in metastases (P=0.005). Immunohistochemistry showed that, in addition to the endothelial cells, vWF protein was also detected in osteosarcoma cells in vivo in 13 of 29 tumor specimens as well as in SAOS2, an osteosarcoma cell line. The tumor cell staining correlated positively with high vWF expression in the sample (P=0.006). Although vascular endothelial cells contribute to the vWF mRNA detected in the tumor samples, there was neither any correlation between vascular density (VD) and vWF mRNA expression nor between VD and clinical outcome. These findings suggest that vWF expression is deregulated in osteosarcoma tumors, potentially contributing to metastasis.

  20. Unwinding the von Willebrand factor strings puzzle.

    PubMed

    De Ceunynck, Karen; De Meyer, Simon F; Vanhoorelbeke, Karen

    2013-01-10

    von Willebrand factor (VWF) is amongst others synthesized by endothelial cells and stored as ultra-large (UL) VWF multimers in Weibel-Palade bodies. Although UL-VWF is proteolysed by ADAMTS13 (a disintegrin-like and metalloprotease domain with thrombospondin type-1 motif, number 13) on secretion from endothelial cells, in vitro experiments in the absence of ADAMTS13 have demonstrated that a proportion of these UL-VWF multimers remain anchored to the activated endothelium. These multimers unravel, bind platelets, and wave in the direction of the flow. These so-called VWF "strings" have also been visualized in vivo, lining the lumen of activated mesenteric veins of Adamts13(-/-) mice. Various studies have demonstrated the extraordinary length of these VWF strings, the availability of their platelet binding and ADAMTS13 cleavage sites, and the possible nature of their endothelial attachment. VWF strings are also capable of tethering leukocytes and parasite-infected red blood cells. However, the majority of studies have been performed in the absence of ADAMTS13, a condition only experienced in thrombotic thrombocytopenic purpura. A normal functional role of VWF strings in healthy persons or in other disease pathologies remains unclear. In this review, we discuss some of the puzzling characteristics of VWF strings, and we debate whether the properties of VWF strings in the absence of ADAMTS13 might be relevant for understanding (patho)physiologic mechanisms.