Science.gov

Sample records for petrostructural studies constraints

  1. Quantitative petrostructure analysis. Technical summary report

    SciTech Connect

    Warren, N.

    1980-09-01

    The establishment of quantitative techniques would lead to the development of predictive tools which would be of obvious importance in applied geophysics and engineering. In rock physics, it would help establish laws for averaging the effects of finite densities of real cracks and pores. It would also help in elucidating the relation between observed complex crack structures and various models for the mechanical properties of single cracks. The petrostructure study is addressed to this problem. The purpose of the effort is to quantitatively characterize the mineral and crack texture of granitic rock samples. The rock structures are to be characterized in such a way that the results can be used (1) to constrain the modelling of the effect of cracks on the physical properties of rocks, and (2) to test the possibility of establishing quantitative and predictive relations between petrographic observables and whole rock properties. Statistical techniques are being developed and being applied to the problem of parameterizing complex texture and crack patterns of rock, and of measuring correlation of these parameters to other measurable variables. The study is an application in factor analysis.

  2. A petro-structural review of the Zermatt-Saas Fee zone

    NASA Astrophysics Data System (ADS)

    Schenker, Filippo Luca; Markus Schmalholz, Stefan; Baumgartner, Lukas

    2014-05-01

    The Zermatt-Saas Fee zone (ZSZ) is an imbricate of fragments of blueschist- to eclogite-facies metabasalts and metagabbros, serpentinites and mélange zones containing blocks of the above mentioned rocks. The ZSZ is usually interpreted as a fragment of oceanic crust belonging to the Piemont-Ligurian (Tethyan) Ocean that was accreted into the Alpine nappe pile. In the last decades the discovery of several Ultra-High Pressure (UHP, >2.7 GPa at 550-600 °C from coesite bearing eclogites and diamond-bearing fluid inclusions in garnet) localities lead to the interpretation of deep subduction (> 100 km) of the ZSZ in the Eocene, and subsequent uplift from mantle depth with high exhumation rates (e.g. Amato et al., 1999). However, these high pressures are in apparent contrast to the regional metamorphic conditions that reflect pressures peaking at < 2 GPa for 550-600°C (blueschist and eclogite mineral assemblages in mafic rocks). These latter metamorphic conditions do not need anomalous high burial histories and exhumation velocities higher than the plate velocities. The magnitude and distribution of pressure in the tectonic units of the ZSZ are important for constraining dynamic models for the evolution of the ZSZ and the Western Alps. Before entering into dynamic models, we propose a petro-structural overview where the published petrological data on pressure and temperature are critically reviewed, and positioned on a geological map and cross section in order to integrate them into the proper structural and tectonic framework. The questions we seek to answer are: How is the pressure distributed within the main tectonic units and within the entire ZSZ? Do we observe sharp or gradual pressure gradients within the ZSZ? Can the UHP conditions be averaged/extended to the entire ZSZ? If not, do they correspond to conditions of observable subunits, or do they reflect anomalies in the pressure field? Answering these questions is fundamental to better understand the

  3. A Diary Study of Difficulties and Constraints in EFL Learning

    ERIC Educational Resources Information Center

    Huang, Jing

    2005-01-01

    Drawing on learners' course diaries, this paper explores Chinese EFL learners' perceptions of difficulties and constraints in EFL learning and their responses to the perceived difficulties and constraints. The diary data appear to indicate that the students' learning difficulties lay mainly with their linguistic competence, but a closer scrutiny…

  4. Bond constraint theory studies of chalcogenide phase change memories

    SciTech Connect

    Paesler, M.A.; Baker, D.A.; Lucovsky, G.

    2008-07-08

    Studies of amorphous (a-) semiconductors have been driven by technological advances as well as fundamental theories. Observation of electrical switching, for example, fueled early interest in a-chalcogenides. More recently a-chalcogenide switching has been applied successfully to programmable memory devices as well as DVD technology where the quest for the discovery of better-suited materials continues. Thus, switching grants researchers today with an active arena of technological as well as fundamental study. Bond constraint theory (BCT) and rigidity theory provide a powerful framework for understanding the structure and properties of a-materials. Application of these theories to switching in a-chalcogenides holds the promise of finding the best composition suited for switching applications. Extended X-ray absorption fine structure (EXAFS) spectroscopy is an ideally suited technique to investigate the switching properties of these materials. Films of amorphous Ge{sub 2}Sb{sub 2}Te{sub 4}, Ge{sub 2}Sb{sub 2}Te{sub 5}, and Ge{sub 2}Sb{sub 2}Te{sub 7} exhibit differing bonding structures and bond statistics, which result in different electronic and optical properties. Results of new EXAFS experiments on these three critical compositions in the Ge-Sb-Te system are presented in light of BCT and rigidity theory.

  5. The Optimization of Multivariate Generalizability Studies with Budget Constraints.

    ERIC Educational Resources Information Center

    Marcoulides, George A.; Goldstein, Zvi

    1992-01-01

    A method is presented for determining the optimal number of conditions to use in multivariate-multifacet generalizability designs when resource constraints are imposed. A decision maker can determine the number of observations needed to obtain the largest possible generalizability coefficient. The procedure easily applies to the univariate case.…

  6. A National Study of Constraints to Participation in Outdoor Recreational Activities

    Treesearch

    Gary T. Green; J.M. Bowker; X.F. Wang; K. Cordell; Cassandra Y. Johnson

    2012-01-01

    A number of studies have shown that certain groups in American society (e.g., Blacks, women, urban dwellers) can encounter barriers or perceived constraints to participation in outdoor recreation. Early research on constraints focused on racial or gender differences. More recent research has examined the effects of income, education, age, and place of residence (Arnold...

  7. Lesbians and Gay Men's Vacation Motivations, Perceptions, and Constraints: A Study of Cruise Vacation Choice.

    PubMed

    Weeden, Clare; Lester, Jo-Anne; Jarvis, Nigel

    2016-08-01

    This study explores the push-pull vacation motivations of gay male and lesbian consumers and examines how these underpin their perceptions and purchase constraints of a mainstream and LGBT(1) cruise. Findings highlight a complex vacation market. Although lesbians and gay men share many of the same travel motivations as their heterosexual counterparts, the study reveals sexuality is a significant variable in their perception of cruise vacations, which further influences purchase constraints and destination choice. Gay men have more favorable perceptions than lesbians of both mainstream and LGBT cruises. The article recommends further inquiry into the multifaceted nature of motivations, perception, and constraints within the LGBT market in relation to cruise vacations.

  8. Narrative Inquiry as Travel Study Method: Affordances and Constraints

    ERIC Educational Resources Information Center

    Craig, Cheryl J.; Zou, Yali; Poimbeauf, Rita

    2014-01-01

    This article maps how narrative inquiry--the use of story to study human experience--has been employed as both method and form to capture cross-cultural learning associated with Western doctoral students' travel study to eastern destinations. While others were the first to employ this method in the travel study domain, we are the first to…

  9. Multicultural Students in Study Abroad: Their Interests, Their Issues, and Their Constraints

    ERIC Educational Resources Information Center

    Brux, Jacqueline Murray; Fry, Blake

    2010-01-01

    Study abroad programs offer great potential to benefit students in an increasingly internationalized world and work place. Recently, a wide discussion among educators about the benefits of diversifying study abroad has developed, but students participating in study abroad may face many constraints, many of which are not faced by their majority…

  10. Multicultural Students in Study Abroad: Their Interests, Their Issues, and Their Constraints

    ERIC Educational Resources Information Center

    Brux, Jacqueline Murray; Fry, Blake

    2010-01-01

    Study abroad programs offer great potential to benefit students in an increasingly internationalized world and work place. Recently, a wide discussion among educators about the benefits of diversifying study abroad has developed, but students participating in study abroad may face many constraints, many of which are not faced by their majority…

  11. A Case Study of Obsolescence Management Constraints During Development of Sustainment-Dominated Systems

    NASA Astrophysics Data System (ADS)

    Welch, Jonathan

    This case study focused on obsolescence management constraints that occur during development of sustainment-dominated systems. Obsolescence management constraints were explored in systems expected to last 20 years or more and that tend to use commercial off-the-shelf products. The field of obsolescence has received little study, but obsolescence has a large cost for military systems. Because developing complex systems takes an average of 3 to 8 years, and commercial off-the-shelf components are typically obsolete within 3 to 5 years, military systems are often deployed with obsolescence issues that are transferred to the sustainment community to determine solutions. The main problem addressed in the study was to identify the constraints that have caused 70% of military systems under development to be obsolete when they are delivered. The purpose of the study was to use a qualitative case study to identify constraints that interfered with obsolescence management occurring during the development stages of a program. The participants of this case study were managers, subordinates, and end-users who were logistics and obsolescence experts. Researchers largely agree that proactive obsolescence management is a lower cost solution for sustainment-dominated systems. Program managers must understand the constraints and understand the impact of not implementing proactive solutions early in the development program lifecycle. The conclusion of the study found several constraints that prevented the development program from early adoption of obsolescence management theories, specifically pro-active theories. There were three major themes identified: (a) management commitment, (b) lack of details in the statement of work, and (c) vendor management. Each major theme includes several subthemes. The recommendation is future researchers should explore two areas: (a) comparing the cost of managing obsolescence early in the development process versus the costs of managing later, (b

  12. Inexact fuzzy-stochastic constraint-softened programming - A case study for waste management

    SciTech Connect

    Li, Y.P. Huang, G.H. Yang, Z.F. Chen, X.

    2009-07-15

    In this study, an inexact fuzzy-stochastic constraint-softened programming method is developed for municipal solid waste (MSW) management under uncertainty. The developed method can deal with multiple uncertainties presented in terms of fuzzy sets, interval values and random variables. Moreover, a number of violation levels for the system constraints are allowed. This is realized through introduction of violation variables to soften system constraints, such that the model's decision space can be expanded under demanding conditions. This can help generate a range of decision alternatives under various conditions, allowing in-depth analyses of tradeoffs among economic objective, satisfaction degree, and constraint-violation risk. The developed method is applied to a case study of planning a MSW management system. The uncertain and dynamic information can be incorporated within a multi-layer scenario tree; revised decisions are permitted in each time period based on the realized values of uncertain events. Solutions associated with different satisfaction degree levels have been generated, corresponding to different constraint-violation risks. They are useful for supporting decisions of waste flow allocation and system-capacity expansion within a multistage context.

  13. Formulation of detailed consumables management models for the development (preoperational) period of advanced space transportation system. Volume 3: Study of constraints/limitations for STS consumables management

    NASA Technical Reports Server (NTRS)

    Newman, C. M.

    1976-01-01

    The constraints and limitations for STS Consumables Management are studied. Variables imposing constraints on the consumables related subsystems are identified, and a method determining constraint violations with the simplified consumables model in the Mission Planning Processor is presented.

  14. A Pilot Study Examining the Effects of Time Constraints on Student Performance in Accounting Classes

    ERIC Educational Resources Information Center

    Morris, David E., Sr.; Scott, John

    2015-01-01

    The purpose of this study was to examine the effects, if any, of time constraints on the success of accounting students completing exams. This study examined how time allowed to take exams affected the grades on examinations in three different accounting classes. Two were sophomore classes and one was a senior accounting class. This limited pilot…

  15. Experimental study of scheduling with memory constraints using hybrid methods

    NASA Astrophysics Data System (ADS)

    Berlinska, J.; Drozdowski, M.; Lawenda, M.

    2009-10-01

    In this paper we study divisible load scheduling in systems with limited memory. Divisible loads are parallel computations which can be divided into independent parts processed in parallel on remote computers, and the part sizes may be arbitrary. The distributed system is a heterogeneous single level tree. The total size of processor memories is too small to accommodate the whole load at any moment of time. Therefore, the load is distributed in many rounds. Memory reservations have block nature. The problem consists in distributing the load taking into account communication time, computation time, and limited memory buffers so that the whole processing finishes as early as possible. This problem is both combinatorial and algebraic in nature. Therefore, hybrid algorithms are given to solve it. Two algorithms are proposed to solve the combinatorial component. A branch-and-bound algorithm is nearly unusable due to its complexity. Then, a genetic algorithm is proposed with more tractable execution times. For a given solution of the combinatorial part we formulate the solution of the algebraic part as a linear programming problem. An extensive computational study is performed to analyze the impact of various system parameters on the quality of the solutions. From this we were able to infer on the nature of the scheduling problem.

  16. A Trade-Off Study Revealing Nested Timescales of Constraint

    PubMed Central

    Wijnants, M. L.; Cox, R. F. A.; Hasselman, F.; Bosman, A. M. T.; Van Orden, G.

    2012-01-01

    This study investigates human performance in a cyclic Fitts task at three different scales of observation, either in the presence (difficult condition) or in the absence (easy condition) of a speed–accuracy trade-off. At the fastest scale, the harmonicity of the back and forth movements, which reflects the dissipation of mechanical energy, was measured within the timeframe of single trials. At an intermediate scale, speed and accuracy measures were determined over a trial. The slowest scale pertains to the temporal structure of movement variability, which evolves over multiple trials. In the difficult condition, reliable correlations across each of the measures corroborated a coupling of nested scales of performance. Participants who predominantly emphasized the speed-side of the trade-off (despite the instruction to be both fast and accurate) produced more harmonic movements and clearer 1/f scaling in the produced movement time series, but were less accurate and produced more random variability in the produced movement amplitudes (vice versa for more accurate participants). This implied that speed–accuracy trade-off was accompanied by a trade-off between temporal and spatial streams of 1/f scaling, as confirmed by entropy measures. In the easy condition, however, no trade-offs nor couplings among scales of performance were observed. Together, these results suggest that 1/f scaling is more than just a byproduct of cognition. These findings rather support the claim that interaction-dominant dynamics constitute a coordinative basis for goal-directed behavior. PMID:22654760

  17. Movement Constraints on Transformations That Do Not Move Elements. Studies in East Asian Syntax.

    ERIC Educational Resources Information Center

    Rodman, Robert

    A number of grammatical transformations are studied which often, but not always, involve the movement of constituents. Data from English, Japanese, Kannada, Korean, Mandarin Chinese and Thai are investigated in an attempt to discover a principle (of potentially universal scope) that governs certain constraints that must be imposed on these…

  18. Understanding Enactivism: A Study of Affordances and Constraints of Engaging Practicing Teachers as Digital Game Designers

    ERIC Educational Resources Information Center

    Li, Qing

    2012-01-01

    This study is intended to deepen our understanding of enactivism, an emergent theoretical paradigm, through empirical exploration of teacher undertakings as digital game creators. Specifically, it explores the affordances and constraints, two important enactivism concepts, of practicing teachers' experiences in designing and developing games for…

  19. Principal Success and Perceptions of Organizational Constraint in City Schools: A Multi-Site Case Study.

    ERIC Educational Resources Information Center

    Weinles, Dan

    This study examined three inner-city public elementary school principals whose schools had most significantly improved across a 2-year period as measured by a district-wide index of performance, investigating their perceptions of organizational constraint and their resulting practices. The performance index was obtained using students' SAT-9…

  20. The efficacy of a panel study for assessing the temporal stability of hunting participation and constraints

    Treesearch

    Ellen B. Drogin Rodgers; Brett A. Wright; Kenneth F. Backman

    2003-01-01

    The intent of this study of Virginia hunters/nonhunters was to test the efficacy of panel research for assessing the temporal stability of hunting participation and constraints. Findings suggest that participation/nonparticipation patterns were stable across time periods for the population, yet dynamic at the individual level. Although the structure of perceived...

  1. A study of the relationships of deer hunters participation intensity and constraints

    Treesearch

    Melissa S. Weddell; Denise M. Anderson; Ellen D. Rodgers; Brett A. Wright

    2007-01-01

    Declines in hunting participation are of concern to wildlife agencies and their ability to fund and manage wildlife populations as well as sustain local hunting traditions. To understand declines in participation, it is important to understand current hunters' perceptions of barriers and constraints that could lead to hunting desertion. This study examined hunting...

  2. Constraints on the evolution of function-valued traits: a study of growth in Tribolium castaneum.

    PubMed

    Irwin, K K; Carter, P A

    2013-12-01

    Growth trajectories often impact individual fitness. They are continuous by nature and so are amenable to analysis using a function-valued (FV) trait framework to reveal their underlying genetic architecture. Previous studies have found high levels of standing additive genetic (co)variance for growth trajectories despite the expectation that growth should be responding to frequent strong directional selection. In this study, the FV framework is used to estimate the additive genetic covariance function for growth trajectories in larval Tribolium castaneum to address questions about standing additive genetic (co)variance and possible evolutionary constraints on growth and to predict responses to four plausible selection regimes. Results show that additive genetic (co)variance is high at the early ages, but decreases towards later ages in the larval period. A selection gradient function of the same size and in the same direction of the first eigenfunction of the G-function should give the maximal response. However, evolutionary constraints may be acting to keep this maximal response from being realized, through either conflicting effects on survivability and fecundity of larger body size, few evolutionary directions having sufficient additive variance for a response, genetic trade-offs with other traits or physiological regulatory mechanisms. More light may be shed on these constraints through the development of more sophisticated statistical approaches and implementation of additional empirical studies to explicitly test for specific types of constraints.

  3. An eye-tracking study of exploitations of spatial constraints in diagrammatic reasoning.

    PubMed

    Shimojima, Atsushi; Katagiri, Yasuhiro

    2013-03-01

    Semantic studies on diagrammatic notations (Barwise & Etchemendy, 1990; Shimojima, 1995; Stenning & Lemon, 2001) have revealed that the "non-deductive," "emergent," or "perceptual" effects of diagrams (Chandrasekaran, Kurup, Banerjee, Josephson, & Winkler, 2004; Kulpa, 2003; Larkin & Simon, 1987; Lindsay, 1988) are all rooted in the exploitation of spatial constraints on graphical structures. Thus, theoretically, this process is a key factor in inference with diagrams, explaining the frequently observed reduction of inferential load. The purpose of this study was to examine the empirical basis for this theoretical suggestion, focusing on the reality of the constraint-exploitation strategy in actual practices of diagrammatic reasoning. Eye movements were recorded while participants used simple position diagrams to solve three- or four-term transitive inference problems. Our experiments revealed that the participants could exploit spatial constraints on graphical structures even when (a) they were not in the position of actually manipulating diagrams, (b) the semantic rule for the provided diagrams did not match their preferences, and (c) the constraint-exploitation strategy invited a partly adverse effect. These findings indicate that the hypothesized process is in fact robust, with the potential to broadly account for the inferential advantage of diagrams. Copyright © 2013 Cognitive Science Society, Inc.

  4. Mental health, constraints, and organization of work as interactive variables. A study of word processing secretaries.

    PubMed

    Billette, A; Carrier, M; Bernier, M; de Sève, M

    1992-07-01

    The effect of a work constraint is specific to the type of work organization. This article deals with the effects of different types of work organization on the mental health of secretaries. The advantage of choosing secretarial work as a research subject lies in the fact that we can identify three distinct types of work organization: (1) a secretary working directly for someone (the "paired" secretary-boss), (2) the "pool," geared toward keyboard input with no specific pairing of secretaries and authors, and (3) the departmental "team," a hybrid of the two preceding types, characterized by the presence of several secretaries, each one assigned to several authors. A study was conducted on the health problems reported by secretaries in the Québec civil service. Data available from a Santé Québec study, carried out at the same time, allowed us to constitute a general population reference group of secretaries and other working women. The findings indicate that secretaries in the general population are no more at risk than are other similar working women, but that secretaries in the provincial civil service are at risk. Regression analysis shows that the same traditional constraints do not affect secretaries in the same way regardless of whether they are members of pair, pool, or team organizations. This suggests that the context of work organization is an interactive or a "specifying variable" of the effect of work constraints on the secretaries' mental health.

  5. Influence of Hatha yoga on physical activity constraints, physical fitness, and body image of breast cancer survivors: a pilot study.

    PubMed

    Van Puymbroeck, Marieke; Schmid, Arlene; Shinew, Kimberly J; Hsieh, Pei-Chun

    2011-01-01

    Breast cancer survivors often experience changes in their perception of their bodies following surgical treatment. These changes in body image may increase self-consciousness and perceptions of physical activity constraints and reduce participation in physical activity. While the number of studies examining different types of yoga targeting women with breast cancer has increased, studies thus far have not studied the influence that Hatha yoga has on body image and physical activity constraints. The objective of this study was to explore the changes that occur in breast cancer survivors in terms of body image, perceived constraints, and physical fitness following an 8-week Hatha yoga intervention. This study used a nonrandomized two-group pilot study, comparing an 8-week Hatha yoga intervention with a light exercise group, both designed for women who were at least nine months post-treatment for breast cancer. Both quantitative and qualitative data were collected in the areas of body image, physical activity constraints, and physical fitness. Findings indicated that quantitatively, yoga participants experienced reductions in physical activity constraints and improvements in lower- and upper-body strength and flexibility, while control participants experienced improvements in abdominal strength and lower-body strength. Qualitative findings support changes in body image, physical activity constraints, and physical fitness for the participants in the yoga group. In conclusion, Hatha yoga may reduce constraints to physical activity and improve fitness in breast cancer survivors. More research is needed to explore the relationship between Hatha yoga and improvements in body image.

  6. A Comparative Study of Randomized Constraint Solvers for Random-Symbolic Testing

    NASA Technical Reports Server (NTRS)

    Takaki, Mitsuo; Cavalcanti, Diego; Gheyi, Rohit; Iyoda, Juliano; dAmorim, Marcelo; Prudencio, Ricardo

    2009-01-01

    The complexity of constraints is a major obstacle for constraint-based software verification. Automatic constraint solvers are fundamentally incomplete: input constraints often build on some undecidable theory or some theory the solver does not support. This paper proposes and evaluates several randomized solvers to address this issue. We compare the effectiveness of a symbolic solver (CVC3), a random solver, three hybrid solvers (i.e., mix of random and symbolic), and two heuristic search solvers. We evaluate the solvers on two benchmarks: one consisting of manually generated constraints and another generated with a concolic execution of 8 subjects. In addition to fully decidable constraints, the benchmarks include constraints with non-linear integer arithmetic, integer modulo and division, bitwise arithmetic, and floating-point arithmetic. As expected symbolic solving (in particular, CVC3) subsumes the other solvers for the concolic execution of subjects that only generate decidable constraints. For the remaining subjects the solvers are complementary.

  7. Dynamic Constraint Satisfaction with Reasonable Global Constraints

    NASA Technical Reports Server (NTRS)

    Frank, Jeremy

    2003-01-01

    Previously studied theoretical frameworks for dynamic constraint satisfaction problems (DCSPs) employ a small set of primitive operators to modify a problem instance. They do not address the desire to model problems using sophisticated global constraints, and do not address efficiency questions related to incremental constraint enforcement. In this paper, we extend a DCSP framework to incorporate global constraints with flexible scope. A simple approach to incremental propagation after scope modification can be inefficient under some circumstances. We characterize the cases when this inefficiency can occur, and discuss two ways to alleviate this problem: adding rejection variables to the scope of flexible constraints, and adding new features to constraints that permit increased control over incremental propagation.

  8. Nonlinear tearing mode study using the almost ideal magnetohydrodynamics (MHD) constraint

    SciTech Connect

    Ren, C.; Callen, J.D.; Jensen, T.H.

    1998-12-31

    The tearing mode is an important resistive magnetohydrodynamics (MHD) mode. It perturbs the initial equilibrium magnetic flux surfaces through magnetic field line reconnection to form new flux surfaces with magnetic islands. In the study of the tearing mode, usually the initial equilibria are one dimensional with two ignorable coordinates and the perturbed equilibria are two dimensional with one ignorable coordinate. The tearing mode can be linearly unstable and its growth saturates at a fine amplitude. The neoclassical tearing mode theory shows that the mode can be nonlinearly driven by the bootstrap current even when it is linearly stable to the classical tearing mode. It is important to study the nonlinear behavior of the tearing mode. As an intrinsically nonlinear approach, the use of the almost ideal MHD constraint is suited to study the nonlinear properties of the tearing mode. In this paper, as a validation of the method, the authors study two characteristics of the tearing mode using the almost ideal MHD constraint: (1) the linear stability condition for the initial one dimensional equilibrium; and (2) the final saturation level for the unstable case. In this work, they only consider the simplest case where no gradient of pressure or current density exists at the mode resonant surface.

  9. A Comparative Theoretical and Computational Study on Robust Counterpart Optimization: II. Probabilistic Guarantees on Constraint Satisfaction

    PubMed Central

    Li, Zukui; Floudas, Christodoulos A.

    2012-01-01

    Probabilistic guarantees on constraint satisfaction for robust counterpart optimization are studied in this paper. The robust counterpart optimization formulations studied are derived from box, ellipsoidal, polyhedral, “interval+ellipsoidal” and “interval+polyhedral” uncertainty sets (Li, Z., Ding, R., and Floudas, C.A., A Comparative Theoretical and Computational Study on Robust Counterpart Optimization: I. Robust Linear and Robust Mixed Integer Linear Optimization, Ind. Eng. Chem. Res, 2011, 50, 10567). For those robust counterpart optimization formulations, their corresponding probability bounds on constraint satisfaction are derived for different types of uncertainty characteristic (i.e., bounded or unbounded uncertainty, with or without detailed probability distribution information). The findings of this work extend the results in the literature and provide greater flexibility for robust optimization practitioners in choosing tighter probability bounds so as to find less conservative robust solutions. Extensive numerical studies are performed to compare the tightness of the different probability bounds and the conservatism of different robust counterpart optimization formulations. Guiding rules for the selection of robust counterpart optimization models and for the determination of the size of the uncertainty set are discussed. Applications in production planning and process scheduling problems are presented. PMID:23329868

  10. Translational constraint influences dynamic spinal canal occlusion of the thoracic spine: an in vitro experimental study.

    PubMed

    Zhu, Qingan; Lane, Chris; Ching, Randal P; Gordon, Jeff D; Fisher, Charles G; Dvorak, Marcel F; Cripton, Peter A; Oxland, Thomas R

    2008-01-01

    Mechanical constraints to spine motion can arise in a variety of real-world situations such as when shoulder belts prevent anterior translation of the thorax during automotive collisions. The effect of such constraint on spinal column-spinal cord interaction during injury remains unknown. The purpose of the present study was to compare maximal dynamic spinal canal occlusion, measured via a specialized transducer, in cadaveric upper thoracic spine specimens under a variety of anterior-posterior constraint conditions. Four injury models were produced using 24 cadaveric spine specimens (T1-T4). Incremental compressive trauma was applied under constrained (i.e. blocked anterior-posterior translation) flexion-compression, pure-compression and extension-compression, and under unconstrained (i.e. free anterior-posterior translation) flexion-compression. All displacements were applied at 500 mm/s. For all three constrained trauma groups, complete transducer occlusion occurred between 20 and 30 mm of compressive displacement. The extension-compression caused transducer occlusion significantly less than the other constrained models (p < 0.022) at 20 mm compression. For unconstrained flexion-compression, a compression of up to 50 mm resulted in a mean of 26% transducer occlusion. The constrained pure-compression tests led to burst fracture with significant body height loss at T2. The constrained flexion-compression and extension-compression tests caused fracture-dislocation injury at the T2-T3 level. Constrained trauma clearly led to more spinal canal occlusion than the unconstrained in these models, and more severe injury to the spinal column. The results add to our understanding of the effect of column injury pattern on spinal cord injury. This information has clear implications for the design of injury prevention devices.

  11. Performance environment and nested task constraints influence long jump approach run: a preliminary study.

    PubMed

    Panteli, Flora; Smirniotou, Athanasia; Theodorou, Apostolos

    2016-01-01

    The purpose of the study was to investigate possible changes at step pattern and technical performance of the long jump approach run in seven young long jumpers by modifying the performance environment (long jump runway versus track lane) and the nested actions (run-through with take-off versus complete long jump). Our findings suggest that the step pattern and technical aspects of the approach run are affected by environmental context and nested task constraints. In terms of environmental context, it appears that practising the training routine of run-through followed by take-off on the long jump runway allows athletes to simulate competition conditions in terms of step regulation and technical efficacy. The task of run-through followed by take-off on the track lane failed to initiate visual perception, step regulation and technical efficiency at the steps preceding the instant of take-off. In terms of nested task constraints, when run-ups were followed by jump for distance instead of only a take-off, a higher level of consistency was achieved and step regulation was based on perception-action coupling. Practising long jump run-up accuracy at a setting not containing the informational elements of the performance environment fails to develop the key elements of the skill.

  12. Elbow joint stability in relation to forced external rotation: An experimental study of the osseous constraint.

    PubMed

    Deutch, Søren R; Jensen, Steen L; Olsen, Bo S; Sneppen, Otto

    2003-01-01

    The objective of this study was to evaluate the osseous constraint related to forced forearm external rotation as the initial stage in a posterior elbow dislocation. Six joint specimens without soft tissues were examined in a joint analysis system developed for simulation of dislocation. The osseous stability, expressed as the maximal torque needed for pathologic external forearm rotation, increased from varus to valgus stress (P =.0001) and from 10 degrees to 90 degrees of elbow flexion (P =.012) and also tended to increase from forearm supination to pronation. The work of pathologic external forearm rotation until the point of maximal torque decreased from a maximum in full extension to a minimum at 30 degrees of elbow flexion (P =.03). The elbow in a slightly flexed position, varus stress, and forearm external rotation trauma might be the important biomechanical factors in the posterior elbow dislocation, and they might serve as guidelines during clinical investigation for posterolateral instability.

  13. Studies in Creativity and Constraint: An Assessment of the Production of Culture Perspective.

    ERIC Educational Resources Information Center

    Ettema, James S.

    If there is a dominant theme in the research on the "production of culture," it is the tension between creativity and constraint. Constraints are imposed by the structures and processes of culture-producing industries and organizations in the attempt to cope with the uncertainties of generating and marketing cultural products. Yet the…

  14. Studies in Creativity and Constraint: An Assessment of the Production of Culture Perspective.

    ERIC Educational Resources Information Center

    Ettema, James S.

    If there is a dominant theme in the research on the "production of culture," it is the tension between creativity and constraint. Constraints are imposed by the structures and processes of culture-producing industries and organizations in the attempt to cope with the uncertainties of generating and marketing cultural products. Yet the…

  15. A qualitative study of hospital pharmacists and antibiotic governance: negotiating interprofessional responsibilities, expertise and resource constraints.

    PubMed

    Broom, Alex; Plage, Stefanie; Broom, Jennifer; Kirby, Emma; Adams, Jon

    2016-02-06

    Antibiotic treatment options for common infections are diminishing due to the proliferation of antimicrobial resistance (AMR). The impact of Antimicrobial Stewardship (AMS) programs seeking to preserve viable antibiotic drugs by governing their use in hospitals has hitherto been limited. Pharmacists have been delegated a critical role in antibiotic governance in AMS teams within hospitals but the experience of pharmacists in influencing antibiotic use has received limited attention. In this study we explore the experiences of pharmacists in antibiotic decision-making in two Australian hospitals. We conducted 19 semi-structured interviews to explore hospital-based pharmacists' perceptions and experiences of antibiotic use and governance. The analysis was conducted with NVivo10 software, utilising the framework approach. Three major themes emerged in the pharmacist interviews including (1) the responsibilities of pharmacy in optimising antibiotic use and the interprofessional challenges therein; (2) the importance of antibiotic streamlining and the constraints placed on pharmacists in achieving this; and (3) the potential, but often under-utilised expertise, pharmacists bring to antibiotic optimisation. Pharmacists have a critical role in AMS teams but their capacity to enact change is limited by entrenched interprofessional dynamics. Identifying how hospital pharmacy's antibiotic gatekeeping is embedded in the interprofessional nature of clinical decision-making and limited by organisational environment has important implications for the implementation of hospital policies seeking to streamline antibiotic use. Resource constraints (i.e. time limitation and task prioritisation) in particular limit the capacity of pharmacists to overcome the interprofessional barriers through development of stronger collaborative relationships. The results of this study suggest that to enact change in antibiotic use in hospitals, pharmacists must be supported in their negotiations

  16. Theoretic Studies of Full Constraints on a Star Tracker's Influential Error Sources for In-orbit Calibration

    NASA Astrophysics Data System (ADS)

    Zhang, Jun; Cai Hao, Yun; Wang, Li; Long, Ye

    2016-03-01

    To collect star transits data qualified for in-orbit calibration, this study derives the full error constraints to limit star tracker's influential error sources and computes their error boundaries from a theoretical perspective. The full constraints, including not only the minimum variance estimation of position but also the error bound prediction of scale and intensity of Gaussian-shaped starspots, are studied based on the Cramér-Rao Lower Bound (CRLB) theorem. By imposing these constraints on motion, drift in focal length, and other factors, their boundaries could be determined before launch. Therefore, the in-orbit correction accuracy is expected to be close to CRLB through suitable implementation of these constraints. The correctness of the theoretical position error of motion is demonstrated by the data-fitting procedure against test results of star tracker on dynamic performance. The simulation result shows that the drift in focal length can generate an error with the same magnitude as detector noise and thus might be the dominant error source when star tracker is working under stationary circumstance. Using the accuracy performance of some typical star trackers, this study shows that the CRLB constraint may be very effective to estimate the overall position error of a starspot or one axis, valuable data that can be used for online calibration. The overall position uncertainty analysis shows that a weighted method can be employed for calibration, a process where star data can be given a weight in inverse proportion to the CRLB value.

  17. Constraint choice in revision knee arthroplasty: study protocol of a randomised controlled trial assessing the effect of level of constraint on postoperative outcome

    PubMed Central

    Hommel, Hagen; Wilke, Kai; Kunze, Daniel; Hommel, Peggy

    2017-01-01

    Introduction The proper management of total knee arthroplasty (TKA) in patients with severe deformities regarding the preferable prosthetic design and the required amount of constraint is a controversial subject. In the absence of any high-level clinical evidence, we designed a randomised clinical trial to investigate if rotating hinged (RTH) and constrained condylar knee (CCK) designs yield similar outcomes. Methods and analysis This study is a multicentre, randomised clinical trial including two groups of 85 patients. Patients will be randomised to a CCK knee design group or an RTH knee design group. Patients will be followed for 2 years. The study will be designed as an equivalence trial. The primary study outcome will be the postoperative functional outcome as measured by the self-administered Knee Injury and Osteoarthritis Outcome Score. Secondary outcomes will be postoperative joint awareness during various activities of daily living as measured by the Forgotten Joint Score-12, the Knee Society Score, along with the incidence and location of radiolucent lines using the Knee Society TKA radiographic evaluation system. Ethics and dissemination This study is approved by the ethics committee of the Landesärztekammer Brandenburg ((S 10(a)/2013) from 27.08.2013, amended on 25.04.2016) and will be conducted according to the principles of the World Medical Association Declaration of Helsinki and the ISO14155:2011. Trial registration number DRKS00010539. PMID:28348182

  18. Is current biochar soil study addressing global soil constraints for sustainable agriculture?

    NASA Astrophysics Data System (ADS)

    Pan, Genxing; Zhang, Dengxiao; Yan, Ming; Niu, Yaru; Liu, Xiaoyu; van Zwieten, Lukas; Chen, De; Bian, Rongjun; Cheng, Kun; Li, Lianqing; Joseph, Stephen; Zheng, Jinwei; Zhang, Xuhui; Zheng, Jufeng; Crowley, David; Filley, Timothy

    2016-04-01

    Global soil degradation has been increasingly threatened sustainability of world agriculture. Use of biochar from bio-wastes has been proposed as a global option for its great potential in tackling soil degradation and mitigating climate change in agriculture. For last 10 years, there have been greatly increasing interests in application of charred biomass, more recently termed biochar, as a soil amendment for addressing soil constraints for sustainable agriculture. Biochar soil studies could deliver reliable information for appropriate application of biochar to soils where for sustainable agriculture has been challenged. Here we review the literature of 798 publications reporting biochar soil studies by August, 2015 to address potential gaps in understanding of biochar's role in agriculture. We have found some substantial biases and gaps inherent in the current biochar studies. 1) The majority of published studies were from developed regions where the soils are less constrained and were much more frequent in laboratory and glasshouse pot experiments than field studies under realistic agriculture. 2) The published biochar soil studies have used more often small kiln or lab prepared biochar than commercial scale biochars, more often wood and municipal waste derived biochars than crop straw biochars. Overall, the lack of long-term well designed field studies using biochar produced in commercial processes may have limited our current understanding of biochar's potential to enhance global crop production and climate change mitigation. We have also recommended a global alliance between longer-term research experiments and biochar production facilities to foster the uptake of this important technology at a global scale. Keywords: biochar, soil study, literature review, research gap, global perspective, quantitative assessment, sustainable agriculture

  19. Expanded Study on the accumulation effect of tourism under the constraint of structure

    NASA Astrophysics Data System (ADS)

    Wang, Qiang; Yang, Zhenzhi; Huang, Lu

    2017-05-01

    There is a mutual influence between departmental structure and accumulation and growth. Therefore, the accumulation and growth of the tourism industry will be subject to certain restrictions on the industrial structure, and, conversely, it will have an impact on the existing industrial structure. Li Jingyi reported special research in the paper called "Research on tourism growth based on structural constraints" about the relationship between the growth of tourism and the existing industrial structure. It pointed out the specific interdependence between tourism and other economic sectors in terms of accumulation and growth. However, the research of Li Jingyi is based on the trichotomy of social product value. It is too abstract, while the study is understandable in theory. In practice, it is difficult to use the model of the paper to deal with specific problems. Therefore, how to improve the industry association model in the paper of Li and make it more in line with the actual situation becomes our concern. In this paper, the author hopes to improve the model of Li's paper by simplifying the decomposition of social product value. At the same time, it makes a further study on accumulation elasticity and growth elasticity. On this basis, some suggestions are put forward to guide the development of other industries based on the tourism industry.

  20. Constraint-induced movement therapy for children with hemiplegia after traumatic brain injury: a quantitative study.

    PubMed

    Cimolin, Veronica; Beretta, Elena; Piccinini, Luigi; Turconi, Anna Carla; Locatelli, Federica; Galli, Manuela; Strazzer, Sandra

    2012-01-01

    The aims of this study are to quantify the movement limitation of upper limbs in hemiplegic children with traumatic brain injury (TBI) by using a clinical-functional scale and upper limb kinematics and to evaluate the effectiveness of constraint-induced movement therapy (CIMT) on upper limbs. Pre-post study. Clinical rehabilitation research laboratory. Ten children with TBI. The participants were evaluated by clinical examinations (Gross Motor Function Measure, Besta scale, Quality of Upper Extremities Skills Test, and Manual Ability Classification System) and 3D kinematic movement analysis of the upper limb before the CIMT program (pretest: 0.7 years after the injury) and at the end of the program (posttest: 10 weeks later). After the CIMT, most of the clinical measures improved significantly. Some significant improvements were present in terms of kinematics, in particular, in the movement duration and the velocity of movement execution of both tasks; the index of curvature and the average jerk improved, respectively, during reaching and hand-to-mouth task, while the adjusting sway parameter decreased during the 2 movements. Significant improvements were found in upper limb joint excursion after the rehabilitative programme too. Our results suggest that the CIMT program can improve movement efficiency and upper limb function in children after TBI. The integration of the clinical outcomes and upper limb kinematics revealed to be crucial in detecting the effects of the CIMT programme.

  1. The Study of Spectrum Reconstruction Based on Fuzzy Set Full Constraint and Multiendmember Decomposition

    NASA Astrophysics Data System (ADS)

    Sun, Y.; Lin, Y.; Hu, X.; Zhao, S.; Liu, S.; Tong, Q.; Helder, D.; Yan, L.

    2017-09-01

    Hyperspectral imaging system can obtain spectral and spatial information simultaneously with bandwidth to the level of 10 nm or even less. Therefore, hyperspectral remote sensing has the ability to detect some kinds of objects which can not be detected in wide-band remote sensing, making it becoming one of the hottest spots in remote sensing. In this study, under conditions with a fuzzy set of full constraints, Normalized Multi-Endmember Decomposition Method (NMEDM) for vegetation, water, and soil was proposed to reconstruct hyperspectral data using a large number of high-quality multispectral data and auxiliary spectral library data. This study considered spatial and temporal variation and decreased the calculation time required to reconstruct the hyper-spectral data. The results of spectral reconstruction based on NMEDM showed that the reconstructed data has good qualities and certain applications, which makes it possible to carry out spectral features identification. This method also extends the application of depth and breadth of remote sensing data, helping to explore the law between multispectral and hyperspectral data.

  2. Imposing nonlinear constraints when estimating genetic and cultural transmission under assortative mating: a simulation study using Mx and BUGS.

    PubMed

    van den Berg, Stéphanie M

    2009-01-01

    Modeling both genetic and cultural transmission in parent-offspring data in the presence of phenotypic assortment requires the imposition of nonlinear constraints. This article reports a simulation study that determined how well the structural equation modeling software package Mx and the Bayesian-oriented BUGS software package can handle such nonlinear constraints under various conditions. Results generally showed good and comparable results for Mx and BUGS, although BUGS was much slower than Mx. However, since BUGS uses Markov-chain Monte Carlo estimation it could be used for parent-offspring models with non-normal data and/or item-response theory models.

  3. Credit Constraints in Education

    ERIC Educational Resources Information Center

    Lochner, Lance; Monge-Naranjo, Alexander

    2012-01-01

    We review studies of the impact of credit constraints on the accumulation of human capital. Evidence suggests that credit constraints have recently become important for schooling and other aspects of households' behavior. We highlight the importance of early childhood investments, as their response largely determines the impact of credit…

  4. Credit Constraints in Education

    ERIC Educational Resources Information Center

    Lochner, Lance; Monge-Naranjo, Alexander

    2012-01-01

    We review studies of the impact of credit constraints on the accumulation of human capital. Evidence suggests that credit constraints have recently become important for schooling and other aspects of households' behavior. We highlight the importance of early childhood investments, as their response largely determines the impact of credit…

  5. Constraints on the Regulatory Process: A Case Study of Regulation of Cable Television. Publication No. 75-5.

    ERIC Educational Resources Information Center

    Berner, Ricahrd Olin

    A case study approach is used to extensively examine the process by which the Federal Communications Commission (FCC) has regulated cable television. A chronological accounting of cable regulation suggests the constraints under which regulation has taken place. An examination of extra-agency groups which constrain the commission's regulatory…

  6. Methods for Estimating Environmental Effects and Constraints on NexGen: High Density Case Study

    NASA Technical Reports Server (NTRS)

    Augustine, S.; Ermatinger, C.; Graham, M.; Thompson, T.

    2010-01-01

    This document provides a summary of the current methods developed by Metron Aviation for the estimate of environmental effects and constraints on the Next Generation Air Transportation System (NextGen). This body of work incorporates many of the key elements necessary to achieve such an estimate. Each section contains the background and motivation for the technical elements of the work, a description of the methods used, and possible next steps. The current methods described in this document were selected in an attempt to provide a good balance between accuracy and fairly rapid turn around times to best advance Joint Planning and Development Office (JPDO) System Modeling and Analysis Division (SMAD) objectives while also supporting the needs of the JPDO Environmental Working Group (EWG). In particular this document describes methods applied to support the High Density (HD) Case Study performed during the spring of 2008. A reference day (in 2006) is modeled to describe current system capabilities while the future demand is applied to multiple alternatives to analyze system performance. The major variables in the alternatives are operational/procedural capabilities for airport, terminal, and en route airspace along with projected improvements to airframe, engine and navigational equipment.

  7. 3D visualization of the scoliotic spine: longitudinal studies, data acquisition, and radiation dosage constraints

    NASA Astrophysics Data System (ADS)

    Kalvin, Alan D.; Adler, Roy L.; Margulies, Joseph Y.; Tresser, Charles P.; Wu, Chai W.

    1999-05-01

    Decision making in the treatment of scoliosis is typically based on longitudinal studies that involve the imaging and visualization the progressive degeneration of a patient's spine over a period of years. Some patients will need surgery if their spinal deformation exceeds a certain degree of severity. Currently, surgeons rely on 2D measurements, obtained from x-rays, to quantify spinal deformation. Clearly working only with 2D measurements seriously limits the surgeon's ability to infer 3D spinal pathology. Standard CT scanning is not a practical solution for obtaining 3D spinal measurements of scoliotic patients. Because it would expose the patient to a prohibitively high dose of radiation. We have developed 2 new CT-based methods of 3D spinal visualization that produce 3D models of the spine by integrating a very small number of axial CT slices with data obtained from CT scout data. In the first method the scout data are converted to sinogram data, and then processed by a tomographic image reconstruction algorithm. In the second method, the vertebral boundaries are detected in the scout data, and these edges are then used as linear constraints to determine 2D convex hulls of the vertebrae.

  8. A study of payload specialist station monitor size constraints. [space shuttle orbiters

    NASA Technical Reports Server (NTRS)

    Kirkpatrick, M., III; Shields, N. L., Jr.; Malone, T. B.

    1975-01-01

    Constraints on the CRT display size for the shuttle orbiter cabin are studied. The viewing requirements placed on these monitors were assumed to involve display of imaged scenes providing visual feedback during payload operations and display of alphanumeric characters. Data on target recognition/resolution, target recognition, and range rate detection by human observers were utilized to determine viewing requirements for imaged scenes. Field-of-view and acuity requirements for a variety of payload operations were obtained along with the necessary detection capability in terms of range-to-target size ratios. The monitor size necessary to meet the acuity requirements was established. An empirical test was conducted to determine required recognition sizes for displayed alphanumeric characters. The results of the test were used to determine the number of characters which could be simultaneously displayed based on the recognition size requirements using the proposed monitor size. A CRT display of 20 x 20 cm is recommended. A portion of the display area is used for displaying imaged scenes and the remaining display area is used for alphanumeric characters pertaining to the displayed scene. The entire display is used for the character alone mode.

  9. Navigating legal constraints in clinical data warehousing: a case study in personalized medicine

    PubMed Central

    Jefferys, Benjamin R.; Nwankwo, Iheanyi; Neri, Elias; Chang, David C. W.; Shamardin, Lev; Hänold, Stefanie; Graf, Norbert; Forgó, Nikolaus; Coveney, Peter

    2013-01-01

    Personalized medicine relies in part upon comprehensive data on patient treatment and outcomes, both for analysis leading to improved models that provide the basis for enhanced treatment, and for direct use in clinical decision-making. A data warehouse is an information technology for combining and standardizing multiple databases. Data warehousing of clinical data is constrained by many legal and ethical considerations, owing to the sensitive nature of the data being stored. We describe an unconstrained clinical data warehousing architecture, some of the legal constraints that have led us to reconsider this architecture, and the legal and technical solutions to these constraints developed for the clinical data warehouse in the personalized medicine project p-medicine. We also propose some changes to the legal constraints that will further enable clinical research. PMID:24427531

  10. Navigating legal constraints in clinical data warehousing: a case study in personalized medicine.

    PubMed

    Jefferys, Benjamin R; Nwankwo, Iheanyi; Neri, Elias; Chang, David C W; Shamardin, Lev; Hänold, Stefanie; Graf, Norbert; Forgó, Nikolaus; Coveney, Peter

    2013-04-06

    Personalized medicine relies in part upon comprehensive data on patient treatment and outcomes, both for analysis leading to improved models that provide the basis for enhanced treatment, and for direct use in clinical decision-making. A data warehouse is an information technology for combining and standardizing multiple databases. Data warehousing of clinical data is constrained by many legal and ethical considerations, owing to the sensitive nature of the data being stored. We describe an unconstrained clinical data warehousing architecture, some of the legal constraints that have led us to reconsider this architecture, and the legal and technical solutions to these constraints developed for the clinical data warehouse in the personalized medicine project p-medicine. We also propose some changes to the legal constraints that will further enable clinical research.

  11. Constraint-induced therapy versus control intervention in patients with stroke: a functional magnetic resonance imaging study.

    PubMed

    Lin, Keh-Chung; Chung, Hsin-Ying; Wu, Ching-Yi; Liu, Ho-Ling; Hsieh, Yu-Wei; Chen, I-Hsuan; Chen, Chia-Ling; Chuang, Li-Ling; Liu, Jung-Sen; Wai, Yau-Yau

    2010-03-01

    This study compared the effects of a distributed form of constraint-induced therapy with control intervention in motor recovery and brain reorganization after stroke. A two-group randomized controlled trial with pretreatment and posttreatment measures was conducted. Thirteen patients with stroke were randomly assigned to the distributed form of constraint-induced therapy (n = 5) or the control intervention group (n = 8). Outcome measures included the Fugl-Meyer Assessment, the Motor Activity Log, and functional magnetic resonance imaging examination. The number of activation voxels and laterality index were determined from the functional magnetic resonance imaging data for the study of brain reorganization. The distributed form of constraint-induced therapy group exhibited significantly greater improvements in the Fugl-Meyer Assessment and Motor Activity Log than the control intervention group. The functional magnetic resonance imaging data showed that distributed form of constraint-induced therapy significantly increased activation in the contralesional hemisphere during movement of the affected and unaffected hand. The control intervention group showed a decrease in primary sensorimotor cortex activation of the ipsilesional hemisphere during movement of the affected hand. The preliminary findings indicate that brain adaptation may be modulated by specific rehabilitation practices, although generalization of the functional magnetic resonance imaging findings is limited by sample size. Further research is needed to identify the specific neural correlates of the behavioral gains achieved after rehabilitation therapies.

  12. A Model To Address Design Constraints of Training Delivered via Satellite. Study Number Eight.

    ERIC Educational Resources Information Center

    Montler, Joseph; Geroy, Gary D.

    This document: summarizes how some companies are addressing the design constraints involved in using satellite technology to deliver training, presents a model aimed at examining cost effectiveness of the satellite option, and includes a guide to designing instructional materials for delivery by satellite. A survey of 39 organizations, 12…

  13. A Model To Address Design Constraints of Training Delivered via Satellite. Study Number Eight.

    ERIC Educational Resources Information Center

    Montler, Joseph; Geroy, Gary D.

    This document: summarizes how some companies are addressing the design constraints involved in using satellite technology to deliver training, presents a model aimed at examining cost effectiveness of the satellite option, and includes a guide to designing instructional materials for delivery by satellite. A survey of 39 organizations, 12…

  14. Effect of cataract surgery volume constraints on recently graduated ophthalmologists: a population-based cohort study

    PubMed Central

    Campbell, Robert J.; El-Defrawy, Sherif R.; Bell, Chaim M.; Gill, Sudeep S.; Hooper, Philip L.; Whitehead, Marlo; Campbell, Erica de L.P.; Nesdole, Robert; Warder, Daniel; ten Hove, Martin

    2017-01-01

    BACKGROUND: Across Canada, graduates from several medical and surgical specialties have recently had difficulty securing practice opportunities, especially in specialties dependent on limited resources such as ophthalmology. We aimed to investigate whether resource constraints in the health care system have a greater impact on the volume of cataract surgery performed by recent graduates than on established physicians. METHODS: We used population-based administrative data from Ontario for the period Jan. 1, 1994, to June 30, 2013, to compare health services provided by recent graduates and established ophthalmologists. The primary outcome was volume of cataract surgery, a resource-intensive service for which volume is controlled by the province. RESULTS: When cataract surgery volume in Ontario entered a period of government-mandated zero growth in 2007, the mean number of cataract operations performed by recent graduates dropped significantly (−46.37 operations/quarter, 95% confidence interval [CI] −62.73 to −30.00 operations/quarter), whereas the mean rate for established ophthalmologists remained stable (+5.89 operations/quarter, 95% CI 95% CI −1.47 to +13.24 operations/quarter). Decreases in service provision among recent graduates did not occur for services without volume control. The proportion of recent graduates providing exclusively cataract surgery increased over the study period, and recent graduates in this group were 5.24 times (95% CI 2.15 to 12.76 times) more likely to fall within the lowest quartile for cataract surgical volume during the period of zero growth in provincial cataract volume (2007–2013) than in the preceding period (1996–2006). INTERPRETATION: Recent ophthalmology graduates performed many fewer cataract surgery procedures after volume controls were implemented in Ontario. Integrated initiatives involving multiple stakeholders are needed to address the issues facing recently graduated physicians in Canada. PMID:27920012

  15. Constraint-Directed Search: A Case Study of Job-Shop Scheduling.

    DTIC Science & Technology

    1983-12-13

    gap between scheduling systems which simply guide the human scheduler, to a scheduling system that can control operations in realtime. The rest of...ability, leaving much of the work to the human Eicheduler. In this section we will illustrate the nature of the scheduling problem and the constraints which...example, a left-leg is part of a human , or B-52 bombers are part of the nuclear defense triad. structure/sub-structure-of: It specifies a structuring

  16. Impact of an equality constraint on the class-specific residual variances in regression mixtures: A Monte Carlo simulation study

    PubMed Central

    Kim, Minjung; Lamont, Andrea E.; Jaki, Thomas; Feaster, Daniel; Howe, George; Van Horn, M. Lee

    2015-01-01

    Regression mixture models are a novel approach for modeling heterogeneous effects of predictors on an outcome. In the model building process residual variances are often disregarded and simplifying assumptions made without thorough examination of the consequences. This simulation study investigated the impact of an equality constraint on the residual variances across latent classes. We examine the consequence of constraining the residual variances on class enumeration (finding the true number of latent classes) and parameter estimates under a number of different simulation conditions meant to reflect the type of heterogeneity likely to exist in applied analyses. Results showed that bias in class enumeration increased as the difference in residual variances between the classes increased. Also, an inappropriate equality constraint on the residual variances greatly impacted estimated class sizes and showed the potential to greatly impact parameter estimates in each class. Results suggest that it is important to make assumptions about residual variances with care and to carefully report what assumptions were made. PMID:26139512

  17. Energy budgets, growth rates, and thermal constraints: toward an integrative approach to the study of life-history variation.

    PubMed

    Niewiarowski, P H

    2001-04-01

    Variation in thermal constraints on activity has been hypothesized to be an important ecological source of geographic variation in growth rates of juvenile eastern fence lizards Sceloporus undulatus. However, most of the evidence to support this hypothesis is either inferential or indirect. In this study, I quantitatively compared thermal constraints on activity and their relationship to growth rates of free-ranging juvenile fence lizards from two extremes of the range of variation in growth rate (Nebraska and New Jersey) used in a reciprocal transplant experiment. I also examined energy allocation made to growth and storage by yearling lizards. Reduced growth rates in New Jersey of normally fast-growing hatchlings from Nebraska were associated with a more stringent thermal constraint on activity corresponding to a 2-3-h shorter predicted daily activity period in New Jersey compared to Nebraska. The thermal constraint on activity was particularly strong (24% less time available in New Jersey compared to Nebraska) during the period when hatchling lizards emerge (August-October). An 8% reduction in total activity time available over the course of a single year was associated with a 7% reduction in the total amount of energy accumulated by lizards in New Jersey. Differences in the total amount of energy available for allocation were also accompanied by differences in how energy was allocated. Lizards from New Jersey had an allocatable energy pool of approximately 40.34 kJ (88% to growth, 12% to storage, and 0% to reproduction). Lizards from Nebraska had an allocatable pool of 43.44 kJ (22% to growth, 18% to storage, and 60% to reproduction). This study joins others in advocating and illustrating an integrative approach to determining the causes and consequences of life-history variation by combining experimental, comparative, and phylogenetic methods in a single system.

  18. Assessing Multivariate Constraints to Evolution across Ten Long-Term Avian Studies

    PubMed Central

    Teplitsky, Celine; Tarka, Maja; Møller, Anders P.; Nakagawa, Shinichi; Balbontín, Javier; Burke, Terry A.; Doutrelant, Claire; Gregoire, Arnaud; Hansson, Bengt; Hasselquist, Dennis; Gustafsson, Lars; de Lope, Florentino; Marzal, Alfonso; Mills, James A.; Wheelwright, Nathaniel T.; Yarrall, John W.; Charmantier, Anne

    2014-01-01

    Background In a rapidly changing world, it is of fundamental importance to understand processes constraining or facilitating adaptation through microevolution. As different traits of an organism covary, genetic correlations are expected to affect evolutionary trajectories. However, only limited empirical data are available. Methodology/Principal Findings We investigate the extent to which multivariate constraints affect the rate of adaptation, focusing on four morphological traits often shown to harbour large amounts of genetic variance and considered to be subject to limited evolutionary constraints. Our data set includes unique long-term data for seven bird species and a total of 10 populations. We estimate population-specific matrices of genetic correlations and multivariate selection coefficients to predict evolutionary responses to selection. Using Bayesian methods that facilitate the propagation of errors in estimates, we compare (1) the rate of adaptation based on predicted response to selection when including genetic correlations with predictions from models where these genetic correlations were set to zero and (2) the multivariate evolvability in the direction of current selection to the average evolvability in random directions of the phenotypic space. We show that genetic correlations on average decrease the predicted rate of adaptation by 28%. Multivariate evolvability in the direction of current selection was systematically lower than average evolvability in random directions of space. These significant reductions in the rate of adaptation and reduced evolvability were due to a general nonalignment of selection and genetic variance, notably orthogonality of directional selection with the size axis along which most (60%) of the genetic variance is found. Conclusions These results suggest that genetic correlations can impose significant constraints on the evolution of avian morphology in wild populations. This could have important impacts on evolutionary

  19. Study of cluster structure in 13C with AMD+HON-constraint method

    NASA Astrophysics Data System (ADS)

    Chiba, Yohei; Kimura, Masaaki

    2014-12-01

    The 3α + n cluster states of 13C are discussed on the basis of antisymmetrized molecular dynamics with the constraint on the harmonic oscillator quanta. We predict two different kinds of the cluster states, the hoyle analogue state and the linear-chain state. The former is understood as the 0+2 state (Hoyle state) of 12C accompanied by a valence neutron occupying the s-wave. The latter constitute the parity doublet bands of Kπ = 1/2± owing to its parity asymmetric intrinsic structure.

  20. REGRESSION APPROXIMATIONS FOR TRANSPORT MODEL CONSTRAINT SETS IN COMBINED AQUIFER SIMULATION-OPTIMIZATION STUDIES.

    USGS Publications Warehouse

    Alley, William M.

    1986-01-01

    Problems involving the combined use of contaminant transport models and nonlinear optimization schemes can be very expensive to solve. This paper explores the use of transport models with ordinary regression and regression on ranks to develop approximate response functions of concentrations at critical locations as a function of pumping and recharge at decision wells. These response functions combined with other constraints can often be solved very easily and may suggest reasonable starting points for combined simulation-management modeling or even relatively efficient operating schemes in themselves.

  1. Earth Observatory Satellite system definition study. Report 2: Instrument constraints and interfaces

    NASA Technical Reports Server (NTRS)

    1974-01-01

    The instrument constraints and interface specifications for the Earth Observatory Satellite (EOS) are discussed. The Land Use Classification Mission using a 7 band Thematic Mapper and a 4 band High Resolution Pointable Imager is stressed. The mission and performance of the instruments were reviewed and expanded to reflect the instrument as a part of the total remote sensing system. A preliminary EOS interface handbook is provided to describe the mission and system, to specify the spacecraft interfaces to potential instrument contractors, and to describe the instrument interface data required by the system integration contractor.

  2. Multiple Treatments of Pediatric Constraint-Induced Movement Therapy (pCIMT): A Clinical Cohort Study

    PubMed Central

    Ramey, Sharon Landesman; Trucks, Mary Rebekah; Wallace, Dorian Ainsworth

    2015-01-01

    Pediatric constraint-induced movement therapy (pCIMT) is one of the most efficacious treatments for children with cerebral palsy (CP). Distinctive components of pCIMT include constraint of the less impaired upper extremity (UE), high-intensity therapy for the more impaired UE (≥3 hr/day, many days per week, for multiple weeks), use of shaping techniques combined with repetitive task practice, and bimanual transfer. A critical issue is whether multiple treatments of pCIMT produce additional benefit. In a clinical cohort (mean age = 31 mo) of 28 children with asymmetrical CP whose parents sought multiple pCIMT treatments, the children gained a mean of 13.2 (standard deviation [SD] = 4.2) new functional skills after Treatment 1; Treatment 2 produced a mean of 7.3 (SD = 4.7) new skills; and Treatment 3, 6.5 (SD = 4.2). These findings support the conclusion that multiple pCIMT treatments can produce clinically important functional gains for children with hemiparetic CP. PMID:26565094

  3. Constraints on neutrino masses from the study of the nearby large-scale structure and galaxy cluster counts

    NASA Astrophysics Data System (ADS)

    Böhringer, Hans; Chon, Gayoung

    2016-07-01

    The high precision measurements of the cosmic microwave background by the Planck survey yielded tight constraints on cosmological parameters and the statistics of the density fluctuations at the time of recombination. This provides the means for a critical study of structure formation in the Universe by comparing the microwave background results with present epoch measurements of the cosmic large-scale structure. It can reveal subtle effects such as how different forms of Dark Matter may modify structure growth. Currently most interesting is the damping effect of structure growth by massive neutrinos. Different observations of low redshift matter density fluctuations provided evidence for a signature of massive neutrinos. Here we discuss the study of the cosmic large-scale structure with a complete sample of nearby, X-ray luminous clusters from our REFLEX cluster survey. From the observed X-ray luminosity function and its reproduction for different cosmological models, we obtain tight constraints on the cosmological parameters describing the matter density, Ωm, and the density fluctuation amplitude, σ8. A comparison of these constraints with the Planck results shows a discrepancy in the framework of a pure ΛCDM model, but the results can be reconciled, if we allow for a neutrino mass in the range of 0.17 eV to 0.7 eV. Also some others, but not all of the observations of the nearby large-scale structure provide evidence or trends for signatures of massive neutrinos. With further improvement in the systematics and future survey projects, these indications will develop into a definitive measurement of neutrino masses.

  4. Socio-political constraints on primary health care: a case study from Java.

    PubMed

    Williams, G; Satoto

    1980-01-01

    The Alma-Ata 1978 conference emphasized the importance of the concept of primary health care in the health system and overall socioeconomic development of the community. However, theories of development generally do not allow for the complexity of human conditions, and the relevance of contact with the village people. This paper presents the experience of a PHC (primary health care) project on the northern coast of central Java. The case illustrates some of the institutional and sociopolitical constraints which the Indonesian government may face in implementing a PHC program in the next few years, such as village politics; the reluctance of men to allow women to participate in the decision-making process of the program, and; the reluctance of land-owning farmers to allow landless villagers in the decision-making process. The following conditions would create a most favorable sociopolitical climate for starting a PHC program in Indonesia: 1) at the village level, non-pamong desa (village elders), women and landless villagers are encouraged to participate in decision-making processes which affect their interests and to take on positions of responsibility in village affairs; 2) there is a process of frank, 2-way communication marked by mutual respect between government agencies at regency and subdistrict levels village-level organization, and 3) supra-village authorities allow village institution to develop at their own pace, intervening only when interests of poor and underprivileged groups are endangered.

  5. A variable temperature spectroscopic study on Paracoccuspantotrophus pseudoazurin: protein constraints on the blue Cu site.

    PubMed

    Xie, Xiangjin; Hadt, Ryan G; Pauleta, Sofia R; González, Pablo J; Un, Sun; Moura, Isabel; Solomon, Edward I

    2009-10-01

    The blue or Type 1 (T1) copper site of Paracoccuspantotrophus pseudoazurin exhibits significant absorption intensity in both the 450 and 600 nm regions. These are sigma and pi S(Cys) to Cu(2+) charge transfer (CT) transitions. The temperature dependent absorption, EPR, and resonance Raman (rR) vibrations enhanced by these bands indicate that a single species is present at all temperatures. This contrasts the temperature dependent behavior of the T1 center in nitrite reductase [S. Ghosh, X. Xie, A. Dey, Y. Sun, C. Scholes, E. Solomon, Proc. Natl. Acad. Sci. 106 (2009) 4969-4974] which has a thioether ligand that is unconstrained by the protein. The lack of temperature dependence in the T1 site in pseudoazurin indicates the presence of a protein constraint similar to the blue Cu site in plastocyanin where the thioether ligand is constrained at 2.8 A. However, plastocyanin exhibits only pi CT. This spectral difference between pseudoazurin and plastocyanin reflects a coupled distortion of the site where the axial thioether in pseudoazurin is also constrained, but at a shorter Cu-S(Met) bond length. This leads to an increase in the Cu(2+)-S(Cys) bond length, and the site undergoes a partial tetragonal distortion in pseudoazurin. Thus, its ground state wavefunction has both sigma and pi character in the Cu(2+)-S(Cys) bond.

  6. Effects of virtual reality training with modified constraint-induced movement therapy on upper extremity function in acute stage stroke: a preliminary study

    PubMed Central

    Ji, Eun-Kyu; Lee, Sang-Heon

    2016-01-01

    [Purpose] The purpose of this study was to investigate the effects of virtual reality training combined with modified constraint-induced movement therapy on upper extremity motor function recovery in acute stage stroke patients. [Subjects and Methods] Four acute stage stroke patients participated in the study. A multiple baseline single subject experimental design was utilized. Modified constraint-induced movement therapy was used according to the EXplaining PLastICITy after stroke protocol during baseline sessions. Virtual reality training with modified constraint-induced movement therapy was applied during treatment sessions. The Manual Function Test and the Box and Block Test were used to measure upper extremity function before every session. [Results] The subjects’ upper extremity function improved during the intervention period. [Conclusion] Virtual reality training combined with modified constraint-induced movement is effective for upper extremity function recovery in acute stroke patients. PMID:27942143

  7. Effects of virtual reality training with modified constraint-induced movement therapy on upper extremity function in acute stage stroke: a preliminary study.

    PubMed

    Ji, Eun-Kyu; Lee, Sang-Heon

    2016-11-01

    [Purpose] The purpose of this study was to investigate the effects of virtual reality training combined with modified constraint-induced movement therapy on upper extremity motor function recovery in acute stage stroke patients. [Subjects and Methods] Four acute stage stroke patients participated in the study. A multiple baseline single subject experimental design was utilized. Modified constraint-induced movement therapy was used according to the EXplaining PLastICITy after stroke protocol during baseline sessions. Virtual reality training with modified constraint-induced movement therapy was applied during treatment sessions. The Manual Function Test and the Box and Block Test were used to measure upper extremity function before every session. [Results] The subjects' upper extremity function improved during the intervention period. [Conclusion] Virtual reality training combined with modified constraint-induced movement is effective for upper extremity function recovery in acute stroke patients.

  8. Constraint algebra in bigravity

    SciTech Connect

    Soloviev, V. O.

    2015-07-15

    The number of degrees of freedom in bigravity theory is found for a potential of general form and also for the potential proposed by de Rham, Gabadadze, and Tolley (dRGT). This aim is pursued via constructing a Hamiltonian formalismand studying the Poisson algebra of constraints. A general potential leads to a theory featuring four first-class constraints generated by general covariance. The vanishing of the respective Hessian is a crucial property of the dRGT potential, and this leads to the appearance of two additional second-class constraints and, hence, to the exclusion of a superfluous degree of freedom—that is, the Boulware—Deser ghost. The use of a method that permits avoiding an explicit expression for the dRGT potential is a distinctive feature of the present study.

  9. Studies of Constraints from the Terrestrial Planets, Asteroid Belt and Giant Planet Obliquities on the Early Solar System Instability

    NASA Astrophysics Data System (ADS)

    Nesvorny, David

    The planetary instability has been invoked as a convenient way to explain several observables in the present Solar System. This theory, frequently referred to under a broad and somewhat ill-defined umbrella as the ‘Nice model’, postulates that at least one of the ice giants suffered scattering encounters with Jupiter and Saturn. This could explain several things, including the excitation of the proper eccentric mode in Jupiter's orbit, survival of the terrestrial planets during giant planet migration, and, if the instability was conveniently delayed, also the Late Heavy Bombardment of the Moon. These properties/events would be unexpected if the migration histories of the outer planets were ideally smooth (at least no comprehensive model has yet been fully developed to collectively explain them). Additional support for the planetary instability comes from the dynamical properties of the asteroid and Kuiper belts, Trojans, and planetary satellites. We created a large database of dynamical evolutions of the outer planets through and 100 Myr past the instability (Nesvorny and Morbidelli 2012. Many of these dynamical histories have been found to match constraints from the orbits of the outer planets themselves. We now propose to test these different scenarios using constraints from the terrestrial planets, asteroid belt and giant planet obliquities. As we explain in the proposal narrative, we will bring all these constraints together in an attempt to develop a comprehensive model of early Solar System's evolution. This will be a significant improvement over the past work, where different constraints were considered piecewise and in various approximations. Our work has the potential to generate support for the Nice-type instability, or to rule it out, which could help in sparking interest in developing better models. RELEVANCE The proposed research is fundamental to understanding the formation and early evolution of the Solar System. This is a central theme of NASA

  10. Liquid-Liquid Extraction and Solid Phase Extraction for Urinary Organic Acids: A Comparative Study from a Resource Constraint Setting.

    PubMed

    Kumari, Chandrawati; Varughese, Bijo; Ramji, Siddarth; Kapoor, Seema

    2016-10-01

    Pre analytical process of extraction for accurate detection of organic acids is a crucial step in diagnosis of organic acidemias by GCMS analysis. This process is accomplished either by solid phase extraction (SPE) or by liquid-liquid extraction (LLE). Both extraction procedures are used in different metabolic laboratories all over the world. In this study we compared these two extraction procedures in respect of precision, accuracy, percent recovery of metabolites, number of metabolites isolated, time and cost in a resource constraint setup. We observed that the mean recovery from SPE was 84.1 % and by LLE it was 77.4 % (p value <0.05). Moreover, the average number of metabolites isolated by SPE and LLE was 161.8 ± 18.6 and 140.1 ± 20.4 respectively. The processing cost of LLE was economical. In a cost constraint setting using LLE may be the practical option if used for organic acid analysis.

  11. Impact of an equality constraint on the class-specific residual variances in regression mixtures: A Monte Carlo simulation study.

    PubMed

    Kim, Minjung; Lamont, Andrea E; Jaki, Thomas; Feaster, Daniel; Howe, George; Van Horn, M Lee

    2016-06-01

    Regression mixture models are a novel approach to modeling the heterogeneous effects of predictors on an outcome. In the model-building process, often residual variances are disregarded and simplifying assumptions are made without thorough examination of the consequences. In this simulation study, we investigated the impact of an equality constraint on the residual variances across latent classes. We examined the consequences of constraining the residual variances on class enumeration (finding the true number of latent classes) and on the parameter estimates, under a number of different simulation conditions meant to reflect the types of heterogeneity likely to exist in applied analyses. The results showed that bias in class enumeration increased as the difference in residual variances between the classes increased. Also, an inappropriate equality constraint on the residual variances greatly impacted on the estimated class sizes and showed the potential to greatly affect the parameter estimates in each class. These results suggest that it is important to make assumptions about residual variances with care and to carefully report what assumptions are made.

  12. Constraints perceived by psychiatrists working in community mental health services. Development and pilot study of a novel instrument.

    PubMed

    Galeazzi, Gian Maria; Mackinnon, Andrew; Curci, Paolo

    2007-12-01

    An inventory of institutional constraints perceived as limiting therapeutic choices was developed and completed by psychiatrists working in Italian public mental health services. Constraints considered most limiting were social and institutional pressures toward social control, violence risk assessment and prevention, and lack of control over workload. The total mean score of the perceived constraints instrument was significantly negatively correlated with ratings of perceived freedom in therapeutic choices and with overall job satisfaction. Reliability was good (alpha = 0.85). Addressing perceived constraints may result in more choice options to reach therapeutic goals in a collaborative framework with patients, and improve job satisfaction.

  13. A case study of participatory action research in a public new England middle school: empowerment, constraints and challenges.

    PubMed

    Phillips, Evelyn Newman; Berg, Marlene J; Rodriguez, Chiedza; Morgan, Damion

    2010-09-01

    PAR recognizes teachers and students as co-creators in a learning process that builds self-efficacy essential to long-term educational success. In enabling contexts, PAR projects also allow teachers to critically deconstruct societal power, examine how these dynamics are reproduced in the classroom, and work against the silencing of student voices. This case study describes the process of implementing an inquiry-based PAR model into a formal urban middle school program intended to reduce drop out rates. The anthropologist/researchers employed participant observation, interviews, and review of student work to explore the dynamics, challenges, and constraints confronted during the process. The intervention demonstrated the gap between practice and theory in a middle school environment marked by well-defined hierarchies and roles as well as high-stakes testing.

  14. Methodological Complications of Matching Designs under Real World Constraints: Lessons from a Study of Deeper Learning

    ERIC Educational Resources Information Center

    Zeiser, Kristina; Rickles, Jordan; Garet, Michael S.

    2014-01-01

    To help researchers understand potential issues one can encounter when conducting propensity matching studies in complex settings, this paper describes methodological complications faced when studying schools using deeper learning practices to improve college and career readiness. The study uses data from high schools located in six districts…

  15. Do organisational constraints explain the use of restraint? A comparative ethnographic study from three nursing homes in Norway.

    PubMed

    Øye, Christine; Jacobsen, Frode Fadnes; Mekki, Tone Elin

    2017-07-01

    To investigate (1) what kind of restraint is used in three nursing homes in Norway and (2) how staff use restraint under what organisational conditions. Restraint use in residents living with dementia in nursing homes is controversial, and at odds with fundamental human rights. Restraint is a matter of hindering residents' free movement and will by applying either interactional, physical, medical, surveillance or environmental restraint. Previous research has identified use of restraint related to individual resident characteristics such as agitation, aggressiveness and wandering. This model is embedded in an overall mixed-method education intervention design study called Modelling and evaluating evidence-based continuing education program in dementia care (MEDCED), applying ethnography postintervention to examine the use of restraint in 24 nursing homes in Norway. Based on restraint diversity measured in the trial, ethnographic investigation was carried out in three different nursing homes in Norway over a 10-month period to examine restraint use in relation to organisational constraints. Several forms of restraint were observed; among them, interactional restraint was used most frequently. We identified that use of restraint relates to the characteristics of individual residents, such as agitation, aggressiveness and wandering. However, restraint use should also be explained in relation to organisational conditions such as resident mix, staff culture and available human resources. A fluctuating and dynamic interplay between different individual and contextual factors determines whether restraint is used - or not in particular situations with residents living with dementia. Educational initiatives targeting staff to reduce restraint must be sensitive towards fluctuating organisational constraints. © 2016 John Wiley & Sons Ltd.

  16. Dress Warm, Focus on the Fluids and Be Patient: Studying Ice Habitats and Constraints on Microbial Life at Low Temperatures

    NASA Astrophysics Data System (ADS)

    Eicken, H.; Junge, K.; Deming, J.

    2002-12-01

    Studies of low-temperature environments on Earth can help guide exploration of other planetary environments that are of interest in the search for potential traces of life (or absence thereof) elsewhere in the solar system. Ice environments and habitats on Earth range from terrestrial permafrost to the polar ice caps or floating sea and lake ice. Despite the complexity of these different environments, the physical chemistry of unfrozen water - generally deemed a prerequisite for active life - and the pore microstructure can help in describing and categorizing different types of ice from an astrobiological perspective. In northern Alaska, we have studied constraints on microbial life in two types of ice, sea and lake ice, that bracket the range of availability of liquid water and solid surfaces. The latter have been found to be important for bacterial activity at very low temperatures, with active bacterial cells in sea ice documented down to temperatures of -20 C. Standard and epi-fluorescence microscopy adapted to studies at very low in-situ temperatures can help in locating individual cells and yield insight into the distribution of liquids, organisms and potential biomarkers in icy habitats. As the distribution of fluids, organisms and impurities is governed by segregation processes on different spatial scales, such work can aid in the planning of exploration campaigns (e.g., on Mars and Europa) and help guide the identification of intensive-study sites or the design of sampling equipment. Apart from such specific lessons, three major conclusions emerge: (1) The use of improved or new methods continues to push the envelope for activity of microbial life to lower temperatures, boding well for planetary exploration campaigns. (2) While the thermodynamics of water activity in ice may constitute an ultimate boundary, the low-temperature kinetic constraints currently present a significant challenge for the study of low-temperature life processes. This may call for

  17. Constraints to Changing Pedagogical Practices in Higher Education: An Example from Japanese Lesson Study

    ERIC Educational Resources Information Center

    Demir, Kadir; Sutton-Brown, Camille; Czerniak, Charlene

    2012-01-01

    This article describes a qualitative study of college mathematics and science faculty (n = 6) and their engagement in a reform-based program, Japanese lesson study (LS), to change their teaching practices. LS is a process in which a team of four to six teachers jointly design, teach, observe, analyze, and revise a single class lesson. A series of…

  18. Curricula in Schools of Librarianship and Information Studies: An Investigation of Constraints and Possibilities.

    ERIC Educational Resources Information Center

    Davinson, Donald; Roberts, Norman

    1985-01-01

    An investigation was undertaken in 1984 in 14 schools of librarianship and information studies (SLIS) in England and Wales. The extent to which information technology concepts have been incorporated into SLIS syllabuses was studied in conjunction with SLIS heads and by examination of curriculum statements. Six sources are given. (Author/EJS)

  19. Double Object Constructions in L3 English: An Exploratory Study of Morphological and Semantic Constraints

    ERIC Educational Resources Information Center

    Agirre, Ainara Imaz; García Mayo, María del Pilar

    2014-01-01

    The present study examines the acquisition of double object constructions (DOCs) ("Susan gave Peter an apple") by 90 Basque/Spanish learners of English as a third language (L3). The aim of this study was to explore whether (i) learners established a distinction when accepting DOCs vs. prepositional phrase constructions (PPCs)…

  20. Creating a Theme Study Classroom around "Big" Questions: Opportunities and Constraints.

    ERIC Educational Resources Information Center

    Hausfather, Sam

    This paper reports from an observant participant's point of view on a theme study conducted in a fifth-grade classroom at a laboratory elementary school of a small, private liberal arts college in Georgia. The "Theme Study" is a student-centered approach that "emphasizes a coherent and holistic approach to learning through the study…

  1. Constraints on Martian Surface Material from a Study of Volcanic Alteration in Iceland and Hawaii

    NASA Astrophysics Data System (ADS)

    Bishop, J.; Schiffman, P.; Southard, R. J.; Drief, A.; Verosub, K. L.

    2003-07-01

    Volcanic alteration is studied on Hawaii and Iceland in order to provide information about alteration of volcanic material on Mars. Palagonitic, pedogenic and solfataric alteration products include differences in mineralogy and chemistry.

  2. An Eye-Tracking Study of Exploitations of Spatial Constraints in Diagrammatic Reasoning

    ERIC Educational Resources Information Center

    Shimojima, Atsushi; Katagiri, Yasuhiro

    2013-01-01

    Semantic studies on diagrammatic notations (Barwise & Etchemendy,; Shimojima,; Stenning & Lemon, ) have revealed that the "non-deductive," "emergent," or "perceptual" effects of diagrams (Chandrasekaran, Kurup, Banerjee, Josephson, & Winkler,; Kulpa,; Larkin & Simon,; Lindsay, ) are all rooted in the…

  3. An Eye-Tracking Study of Exploitations of Spatial Constraints in Diagrammatic Reasoning

    ERIC Educational Resources Information Center

    Shimojima, Atsushi; Katagiri, Yasuhiro

    2013-01-01

    Semantic studies on diagrammatic notations (Barwise & Etchemendy,; Shimojima,; Stenning & Lemon, ) have revealed that the "non-deductive," "emergent," or "perceptual" effects of diagrams (Chandrasekaran, Kurup, Banerjee, Josephson, & Winkler,; Kulpa,; Larkin & Simon,; Lindsay, ) are all rooted in the…

  4. Development and validation of a computational model to study the effect of foot constraint on ankle injury due to external rotation.

    PubMed

    Wei, Feng; Hunley, Stanley C; Powell, John W; Haut, Roger C

    2011-02-01

    Recent studies, using two different manners of foot constraint, potted and taped, document altered failure characteristics in the human cadaver ankle under controlled external rotation of the foot. The posterior talofibular ligament (PTaFL) was commonly injured when the foot was constrained in potting material, while the frequency of deltoid ligament injury was higher for the taped foot. In this study an existing multibody computational modeling approach was validated to include the influence of foot constraint, determine the kinematics of the joint under external foot rotation, and consequently obtain strains in various ligaments. It was hypothesized that the location of ankle injury due to excessive levels of external foot rotation is a function of foot constraint. The results from this model simulation supported this hypothesis and helped to explain the mechanisms of injury in the cadaver experiments. An excessive external foot rotation might generate a PTaFL injury for a rigid foot constraint, and an anterior deltoid ligament injury for a pliant foot constraint. The computational models may be further developed and modified to simulate the human response for different shoe designs, as well as on various athletic shoe-surface interfaces, so as to provide a computational basis for optimizing athletic performance with minimal injury risk.

  5. Allocation of Study Time in Chinese Junior School Students: Habitual Responding, Item Difficulty, and Time Constraints

    PubMed Central

    Wang, Fuyun; Qin, Qiwen; Jiang, Yanju

    2016-01-01

    The present study investigated factors influencing Chinese junior school students’ study time allocation and the age difference in the effect of habitual responding. Participants were 240 junior school students (120 girls, 120 boys; aged 13–15 years) with half taking part in Experiment 1 and half in Experiment 2, and 240 young adults aged 18–23 years, (120 women and 120 men,) involved in Experiments 3a and 3b, all native Chinese speakers. In Experiments 1 and 3a, Chinese word pairs (e.g., moon–star) were presented on the screen with three items in one array. In each trial, the items were arranged from left to right, either easy, moderate, then difficult, or the reverse. Participants had either 5 s or no time limits to study the word pairs. In Experiments 2 and 3b, word pairs were ordered in a column with the easiest items either at the top or bottom position. Results showed interactions among item difficulty, item order, and time limitation in terms of effects on study time allocation of junior school students. Participants tended to learn the items in order (from left to right and from top to bottom), but the effect of item difficulty was greater than that of item order on item selection. Results indicated that agenda and habitual responding have a combined effect on study time allocation and that the contribution of agenda is greater than that of habitual responding. The effect of habitual responding on the self-paced study and recall performance of junior school students is greater than its effect on young adults, and the study time allocation of junior school students is more likely to be affected by external conditions. PMID:27199865

  6. Allocation of Study Time in Chinese Junior School Students: Habitual Responding, Item Difficulty, and Time Constraints.

    PubMed

    Wang, Fuyun; Qin, Qiwen; Jiang, Yanju

    2016-01-01

    The present study investigated factors influencing Chinese junior school students' study time allocation and the age difference in the effect of habitual responding. Participants were 240 junior school students (120 girls, 120 boys; aged 13-15 years) with half taking part in Experiment 1 and half in Experiment 2, and 240 young adults aged 18-23 years, (120 women and 120 men,) involved in Experiments 3a and 3b, all native Chinese speakers. In Experiments 1 and 3a, Chinese word pairs (e.g., moon-star) were presented on the screen with three items in one array. In each trial, the items were arranged from left to right, either easy, moderate, then difficult, or the reverse. Participants had either 5 s or no time limits to study the word pairs. In Experiments 2 and 3b, word pairs were ordered in a column with the easiest items either at the top or bottom position. Results showed interactions among item difficulty, item order, and time limitation in terms of effects on study time allocation of junior school students. Participants tended to learn the items in order (from left to right and from top to bottom), but the effect of item difficulty was greater than that of item order on item selection. Results indicated that agenda and habitual responding have a combined effect on study time allocation and that the contribution of agenda is greater than that of habitual responding. The effect of habitual responding on the self-paced study and recall performance of junior school students is greater than its effect on young adults, and the study time allocation of junior school students is more likely to be affected by external conditions.

  7. Constraints to Changing Pedagogical Practices in Higher Education: An example from Japanese lesson study

    NASA Astrophysics Data System (ADS)

    Demir, Kadir; Sutton-Brown, Camille; Czerniak, Charlene

    2012-07-01

    This article describes a qualitative study of college mathematics and science faculty (n = 6) and their engagement in a reform-based program, Japanese lesson study (LS), to change their teaching practices. LS is a process in which a team of four to six teachers jointly design, teach, observe, analyze, and revise a single class lesson. A series of semi-structured, open-ended, interviews was completed with each of the faculty participants. Two sets of assertions were developed from analyses of the data and examples and explanations corroborating each assertion are provided. The results of the study identified issues related to organizational and faculty changes that need to be addressed if faculty responses to pedagogical innovations are to succeed. Implications of the findings for practice and future research are discussed.

  8. The Constraints of History: Revision and Revolution in American Literary Studies.

    ERIC Educational Resources Information Center

    Carafiol, Peter

    1988-01-01

    Asserts that rigorous historicism might change the following: (1) American literary study, by dropping the traditional nationalist project; (2) the notion of canon, by abandoning it; (3) and the institutional structure that supports academic literary criticism, by interrogating current critical conversation and, by recuperating its history,…

  9. Identification, Situational Constraint, and Social Cognition: Studies in the Attribution of Moral Responsibility

    ERIC Educational Resources Information Center

    Woolfolk, Robert L.; Doris, John M.; Darley, John M.

    2006-01-01

    In three experiments we studied lay observers' attributions of responsibility for an antisocial act (homicide). We systematically varied both the degree to which the action was coerced by external circumstances and the degree to which the actor endorsed and accepted ownership of the act, a psychological state that philosophers have termed…

  10. Constraints and Meaning-Making: Dealing with the Multifacetedness of Social Studies in Audited Teaching Practices

    ERIC Educational Resources Information Center

    Strandler, Ola

    2017-01-01

    Purpose: The backdrop of the article is the emergence of an international and politically motivated ambition that aims at standardising the purpose and outcomes of teaching practices via various forms of outcome controls. This ambition of standardisation is discussed in a Swedish context in relation to social studies teaching, which, at its core,…

  11. Generalizing Atoms in Constraint Logic

    NASA Technical Reports Server (NTRS)

    Page, C. David, Jr.; Frisch, Alan M.

    1991-01-01

    This paper studies the generalization of atomic formulas, or atoms, that are augmented with constraints on or among their terms. The atoms may also be viewed as definite clauses whose antecedents express the constraints. Atoms are generalized relative to a body of background information about the constraints. This paper first examines generalization of atoms with only monadic constraints. The paper develops an algorithm for the generalization task and discusses algorithm complexity. It then extends the algorithm to apply to atoms with constraints of arbitrary arity. The paper also presents semantic properties of the generalizations computed by the algorithms, making the algorithms applicable to such problems as abduction, induction, and knowledge base verification. The paper emphasizes the application to induction and presents a pac-learning result for constrained atoms.

  12. Thermodynamic Constraints Improve Metabolic Networks.

    PubMed

    Krumholz, Elias W; Libourel, Igor G L

    2017-08-08

    In pursuit of establishing a realistic metabolic phenotypic space, the reversibility of reactions is thermodynamically constrained in modern metabolic networks. The reversibility constraints follow from heuristic thermodynamic poise approximations that take anticipated cellular metabolite concentration ranges into account. Because constraints reduce the feasible space, draft metabolic network reconstructions may need more extensive reconciliation, and a larger number of genes may become essential. Notwithstanding ubiquitous application, the effect of reversibility constraints on the predictive capabilities of metabolic networks has not been investigated in detail. Instead, work has focused on the implementation and validation of the thermodynamic poise calculation itself. With the advance of fast linear programming-based network reconciliation, the effects of reversibility constraints on network reconciliation and gene essentiality predictions have become feasible and are the subject of this study. Networks with thermodynamically informed reversibility constraints outperformed gene essentiality predictions compared to networks that were constrained with randomly shuffled constraints. Unconstrained networks predicted gene essentiality as accurately as thermodynamically constrained networks, but predicted substantially fewer essential genes. Networks that were reconciled with sequence similarity data and strongly enforced reversibility constraints outperformed all other networks. We conclude that metabolic network analysis confirmed the validity of the thermodynamic constraints, and that thermodynamic poise information is actionable during network reconciliation. Copyright © 2017 Biophysical Society. Published by Elsevier Inc. All rights reserved.

  13. Physiological and proteome study of sunflowers exposed to a polymetallic constraint.

    PubMed

    Printz, Bruno; Sergeant, Kjell; Guignard, Cedric; Renaut, Jenny; Hausman, Jean-Francois

    2013-06-01

    The new energy requirements of the growing world population together with the actual ecological trend of phytoremediation have made challenging the cultivation of energetic crops on nonagricultural lands, such as those contaminated with trace elements. In this study, phenotypical characterization and biochemical analyses were combined to emphasize the global response of young sunflowers (Helianthus annuus L.) grown in hydroponic media contaminated with different Cd, Ni, and Zn concentrations. Leaves and roots of sunflowers reaching the stage "2-extended leaves" and exposed to different trace metal concentrations were harvested and analyzed by 2D-DIGE in order to study in depth the molecular responses of the young plants upon the polymetallic exposure. Proteomics confirmed the observed global reduction in growth and development. If photosynthetic light reactions and carbon metabolism were the most affected in leaves, in roots significant disruptions were observed in proteins involved in respiration, oxidative balance, protein and gene expression, and in the induction of programmed cell death. Elemental analyses of the plantlets indicated a profound impact of the treatment resulting in misbalance in essential micronutrients. Altogether, this study highlights the sensitivity of the sunflower to a polymetallic pollution and indicates that its use as a remediative tool of trace element polluted soils is limited.

  14. Constraints on Martian Surface Material from a Study of Volcanic Alteration in Iceland and Hawaii

    NASA Technical Reports Server (NTRS)

    Bishop, J. L.; Schiffman, P.; Southard, R. J.; Drief, A.; Verosub, K. L.

    2003-01-01

    Subaerial volcanic activity on Hawaii and subglacial volcanic activity on Iceland has led to the formation of a variety of silicate and iron oxiderich alteration products that may serve as models for chemical alteration on Mars. Multiple samples have been collected from palagonitic tuffs, altered pillow lavas, altered tephra, and S-rich vents for study in the lab. Variations in the kinds of alteration products have been observed depending on the alteration environment of the sample. We are working on building associations between the alteration products and formation conditions that can be used to provide information about environmental conditions on Mars.

  15. Constraints on Martian Surface Material from a Study of Volcanic Alteration in Iceland and Hawaii

    NASA Technical Reports Server (NTRS)

    Bishop, J. L.; Schiffman, P.; Southard, R. J.; Drief, A.; Verosub, K. L.

    2003-01-01

    Subaerial volcanic activity on Hawaii and subglacial volcanic activity on Iceland has led to the formation of a variety of silicate and iron oxiderich alteration products that may serve as models for chemical alteration on Mars. Multiple samples have been collected from palagonitic tuffs, altered pillow lavas, altered tephra, and S-rich vents for study in the lab. Variations in the kinds of alteration products have been observed depending on the alteration environment of the sample. We are working on building associations between the alteration products and formation conditions that can be used to provide information about environmental conditions on Mars.

  16. Decreased nocturnal awakenings in young adults performing bikram yoga: a low-constraint home sleep monitoring study.

    PubMed

    Kudesia, Ravi S; Bianchi, Matt T

    2012-01-01

    This pilot study evaluated the impact of Bikram Yoga on subjective and objective sleep parameters. We compared subjective (diary) and objective (headband sleep monitor) sleep measures on yoga versus nonyoga days during a 14-day period. Subjects (n = 13) were not constrained regarding yoga-practice days, other exercise, caffeine, alcohol, or naps. These activities did not segregate by choice of yoga days. Standard sleep metrics were unaffected by yoga, including sleep latency, total sleep time, and percentage of time spent in rapid eye movement (REM), light non-REM, deep non-REM, or wake after sleep onset (WASO). Consistent with prior work, transition probability analysis was a more sensitive index of sleep architecture changes than standard metrics. Specifically, Bikram Yoga was associated with significantly faster return to sleep after nocturnal awakenings. We conclude that objective home sleep monitoring is feasible in a low-constraint, real-world study design. Further studies on patients with insomnia will determine whether the results generalize or not.

  17. Constraints on the cerebral basis for semantic processing from neuroimaging studies of Alzheimer's disease

    PubMed Central

    Grossman, M.; Payer, F.; Onishi, K.; White-Devine, T.; Morrison, D.; D'Esposito, M.; Robinson, K.; Alavi, A.

    1997-01-01

    OBJECTIVE—Functional activation studies of semantic processing in healthy adults have yielded conflicting results. The purpose was to evaluate the relative role of the brain regions implicated in semantic processing with converging evidence from imaging studies of patients with impaired semantic processing.
METHODS—Semantic memory was assessed in patients with Alzheimer's disease using two measures, and these performance patterns were related to profiles of reduced cerebral functioning obtained with high resolution single photon emission computed tomography (SPECT). Patients with frontotemporal degeneration were similarly evaluated as a control group.
RESULTS—Reduced relative cerebral perfusion was seen in parietal and posterior temporal brain regions of patients with Alzheimer's disease but not patients with frontotemporal degeneration. Impairments on semantically guided category membership decision tasks were also seen in patients with Alzheimer's disease but not those with frontotemporal degeneration. Performance on the semantic measures correlated with relative cerebral perfusion in inferior parietal and superior temporal regions of the left hemisphere only in Alzheimer's disease. Relative perfusion was significantly lower in these regions in patients with Alzheimer's disease with semantic difficulty compared with patients with Alzheimer's disease with relatively preserved semantic processing.
CONCLUSION—These findings provide converging evidence to support the contribution of superior temporal and inferior parietal regions of the left hemisphere to semantic processing.

 PMID:9285450

  18. Grammatical judgments and phonetic reality: A study of internal constraints in phonological variation

    NASA Astrophysics Data System (ADS)

    File, Richard; Diaz-Campos, Manuel

    2003-10-01

    Previous investigations analyzing phonological variation in Spanish have pointed out that phonetic context is an important factor for predicting different variants of /s/. In many studies (Cedergren, 1973; Poplack, 1979, 1980, 1986; Ranson, 1993; Samper Padilla, 1990; Terrell, 1977, 1978, 1979, 1986, etc.), it is claimed that /s/ aspiration is more likely to happen word-internally, preceding a consonant, while elision is more likely to happen word-finally preceding a pause. The methodology used in those studies relies on grammatical judgment for performing the analysis of phonetic context, which could present a perceptual bias that could misrepresent the reality of the realization of the segments. The present investigation examines the phonetic cues that might have an effect in the perception of syllable-final /s/ including the duration of the preceding vowel as well as the following context. Preliminary results show that when the preceding vowel had a shorter duration, retention was easily perceived, whereas when the preceding vowel was longer in duration, the perception of aspiration was favored. The results suggest that for a segment with the same degree of aspiration, deletion was perceived before a pause more often than before a consonant, especially when the preceding vowel was shorter in duration.

  19. Trace Element Uptake in Marine Bivalve Shells Constraints from Field- and Laboratory Studies

    NASA Astrophysics Data System (ADS)

    Klünder, M.; Hippler, D.; Witbaard, R.; Frei, D.; Immenhauser, A.

    2006-12-01

    There is an increasing interest in the use of the trace element signatures recorded in calcium carbonate skeletons of marine organisms as archives of past and present environmental conditions, such as temperature, salinity or nutrition level. Because of their global occurrence in the modern and ancient oceans, the trace element chemistry of bivalve shells might be used as a potential proxy for present and past environmental conditions. If the composition of bivalve shells, for instance, can be shown to represent the environment in which they lived, then shells can be used to investigate conditions in the lifetime of the animal. And as the shell material is sequentially deposited, an understanding of the internal shell structure will enable time- resolution of the analyses. Therefore, the trace element signature of bivalve shells may provide an important record of climate changes and global geochemical cycles. One of the difficulties of using the trace element signatures of bivalve shells as proxies for environmental conditions is that little is known about the mechanisms by which the trace elements are incorporated into the shells. There has been quite an amount of research into the use of bivalve shell chemistry as proxy for one or more environmental parameters, but there are relatively few datasets in which both bivalve shells and the water in which the animals lived have been analysed. It is as yet not clear to what extent the trace element incorporation into bivalve shells is governed by biological processes, like growth rate and metabolism of the animals, or by physical and crystal chemical parameters. An added difficulty is that the existing data do suggest that trace element uptake in bivalve shells may be species specific. Therefore, studies that investigate the relationships between the content of these elements in the shells and the ambient water and the possible incorporation mechanisms are needed if the potential that bivalve shells offer as

  20. Short-selling constraints as cause for price distortions: An experimental study.

    PubMed

    Hauser, Florian; Huber, Jürgen

    2012-09-01

    In this paper we explore the influence of the possibility to short stocks and/or borrow money in laboratory markets. A key innovation of our study is that subjects can simultaneously trade two risky assets on two double-auction markets, allowing us to differentiate between assets with relatively high versus low capitalization. Divergence of opinions is created by providing each trader with noisy information on the intrinsic values of both assets. We find that when borrowing money or shorting stocks is restricted prices are systematically distorted. Specifically, stocks with high (low) capitalization are traded at lower (higher) prices than their fundamental value. Lifting the restrictions leads to more efficient prices and more liquidity, thereby also lowering volatility and bid-ask spreads.

  1. Short-selling constraints as cause for price distortions: An experimental study

    PubMed Central

    Hauser, Florian; Huber, Jürgen

    2012-01-01

    In this paper we explore the influence of the possibility to short stocks and/or borrow money in laboratory markets. A key innovation of our study is that subjects can simultaneously trade two risky assets on two double-auction markets, allowing us to differentiate between assets with relatively high versus low capitalization. Divergence of opinions is created by providing each trader with noisy information on the intrinsic values of both assets. We find that when borrowing money or shorting stocks is restricted prices are systematically distorted. Specifically, stocks with high (low) capitalization are traded at lower (higher) prices than their fundamental value. Lifting the restrictions leads to more efficient prices and more liquidity, thereby also lowering volatility and bid-ask spreads. PMID:26523081

  2. Regulatory science and radiation protection: A study of dose constraints for members of the public and occupationally-exposed workers at the U.S. nuclear power plants

    NASA Astrophysics Data System (ADS)

    Kong, Tae Young

    The U.S. Nuclear Regulatory Commission (NRC) is considering a revision of the existing system of radiation protection regulations with respect to ICRP Publication 103. It is expected that there will be a change in the current NRC regulations to require the implementation of concept of dose constraints for members of the public and for occupationally-exposed workers at the U.S. nuclear power plants (NPPs). Under the paradigm of regulatory science, the use of dose constraints is still highly debatable. This study addressed two objectives. The first objective was determining whether or not dose constraints are necessary for members of the public and occupationally-exposed workers at the U.S. NPPs. The second objective was determining, if dose constraints were needed, the optimal numerical values of dose constraints at the U.S. NPPs. To achieve these objectives, several areas were investigated and analyzed: 1) the establishment of a regulatory-science framework; 2) a system of radiation protection which would incorporate the concept of dose constraints; 3) methodologies and regulations for public and occupational dose assessment; 4) approaches to the establishment of dose constraints; 5) the actual doses for members of the public living around NPPs; and 6) the range of doses for occupationally-exposed workers in NPPs. As a result of analysis of exposure data, the annual median and maximum doses to a maximally-exposed individual (MEI) for members of the public were 10-4 and 10-1 mSv, respectively. The corresponding annual excess risks (ER) for the median and maximum doses were calculated to be on the order of 10-8 and 10-6 , respectively. These excess risks are low and should be considered acceptable. For occupationally-exposed workers, the average and maximum measurable doses were 1.3 mSv and 24.8 mSv, respectively. The annual excess risks for the average and maximum doses were 10-5 and 10-3, respectively. These excess risks are also acceptable from the perspective of

  3. Isotopic constraints on the deep crustal structure of Gondwana: case studies from Yemen and Saudi Arabia

    NASA Astrophysics Data System (ADS)

    Whitehouse, M.

    2003-04-01

    The late Precambrian assembly of east and west Gondwana created a tectonic collage of oceanic arcs and micro-continental fragments over most of the exposed Arabian Shield. Sutures within this collage may be identified by ophiolitic remnants or elsewhere inferred by lithological packages such as characteristic arc volcanics. However, the significance of individual sutures, for example as intra-oceanic or oceanic-continental boundaries is often unclear. The present study utilises isotopic data (Pb and Nd) and geochronology (U-Pb zircon) on syn- and post-tectonic granitoids from two localities in the Arabian Shield in order to constrain the nature of their deep crustal source regions and, hence, the regional significance of sutures. In the southern part of the Shield in Saudi Arabia, the Nabitah fault zone (NFZ) separates rocks of the Tarib arc from those of the Tathlith terrane. Interpretation of the NFZ ranges from a simple fault to a southward extension of the Nabitah suture zone which, further north, is thought to represent the boundary between east and west Gondwana. New isotopic data from ca. 650 Ma granitoids either side of the NFZ reveal two ensimatic arcs with different isotopic characteristics, notably significantly lower ɛ{Nd}(t) and elevated 208Pb/204Pb to the east. These data suggest that the NFZ indeed represents a suture and major terrane boundary that may be the southward extension of the Nabitah suture. The Neoproterozoic Al Bayda arc terrane of central Yemen separates two terranes of continental affinity, the Neoproterozoic Abas and late Archean Al Mahfid. The Abas terrane was accreted to east Gondwana prior to final closure of the Pan African ocean, while the Al Mahfid terrane may be an integral part of east Gondana. Previous isotopic studies of these continental terranes has revealed highly distinctive isotopic signatures requiring a suture along the line of the Al Bayda arc, probably at ca. 760 Ma. Extensive metavolcanic rocks in the Al Bayda

  4. Motivations and Constraints to Family Planning: A Qualitative Study in Rwanda's Southern Kayonza District.

    PubMed

    Farmer, Didi Bertrand; Berman, Leslie; Ryan, Grace; Habumugisha, Lameck; Basinga, Paulin; Nutt, Cameron; Kamali, Francois; Ngizwenayo, Elias; St Fleur, Jacklin; Niyigena, Peter; Ngabo, Fidele; Farmer, Paul E; Rich, Michael L

    2015-05-13

    While Rwanda has achieved impressive gains in contraceptive coverage, unmet need for family planning is high, and barriers to accessing quality reproductive health services remain. Few studies in Rwanda have qualitatively investigated factors that contribute to family planning use, barriers to care, and quality of services from the community perspective. We undertook a qualitative study of community perceptions of reproductive health and family planning in Rwanda's southern Kayonza district, which has the country's highest total fertility rate. From October 2011 to December 2012, we conducted interviews with randomly selected male and female community members (n = 96), community health workers (n = 48), and health facility nurses (n = 15), representing all 8 health centers' catchment areas in the overall catchment area of the district's Rwinkwavu Hospital. We then carried out a directed content analysis to identify key themes and triangulate findings across methods and informant groups. Key themes emerged across interviews surrounding: (1) fertility beliefs: participants recognized the benefits of family planning but often desired larger families for cultural and historical reasons; (2) social pressures and gender roles: young and unmarried women faced significant stigma and husbands exerted decision-making power, but many husbands did not have a good understanding of family planning because they perceived it as a woman's matter; (3) barriers to accessing high-quality services: out-of-pocket costs, stock-outs, limited method choice, and long waiting times but short consultations at facilities were common complaints; (4) side effects: poor management and rumors and fears of side effects affected contraceptive use. These themes recurred throughout many participant narratives and influenced reproductive health decision making, including enrollment and retention in family planning programs. As Rwanda continues to refine its family planning policies and

  5. Motivations and Constraints to Family Planning: A Qualitative Study in Rwanda’s Southern Kayonza District

    PubMed Central

    Farmer, Didi Bertrand; Berman, Leslie; Ryan, Grace; Habumugisha, Lameck; Basinga, Paulin; Nutt, Cameron; Kamali, Francois; Ngizwenayo, Elias; Fleur, Jacklin St; Niyigena, Peter; Ngabo, Fidele; Farmer, Paul E; Rich, Michael L

    2015-01-01

    Background: While Rwanda has achieved impressive gains in contraceptive coverage, unmet need for family planning is high, and barriers to accessing quality reproductive health services remain. Few studies in Rwanda have qualitatively investigated factors that contribute to family planning use, barriers to care, and quality of services from the community perspective. Methods: We undertook a qualitative study of community perceptions of reproductive health and family planning in Rwanda’s southern Kayonza district, which has the country’s highest total fertility rate. From October 2011 to December 2012, we conducted interviews with randomly selected male and female community members (n = 96), community health workers (n = 48), and health facility nurses (n = 15), representing all 8 health centers’ catchment areas in the overall catchment area of the district’s Rwinkwavu Hospital. We then carried out a directed content analysis to identify key themes and triangulate findings across methods and informant groups. Results: Key themes emerged across interviews surrounding: (1) fertility beliefs: participants recognized the benefits of family planning but often desired larger families for cultural and historical reasons; (2) social pressures and gender roles: young and unmarried women faced significant stigma and husbands exerted decision-making power, but many husbands did not have a good understanding of family planning because they perceived it as a woman’s matter; (3) barriers to accessing high-quality services: out-of-pocket costs, stock-outs, limited method choice, and long waiting times but short consultations at facilities were common complaints; (4) side effects: poor management and rumors and fears of side effects affected contraceptive use. These themes recurred throughout many participant narratives and influenced reproductive health decision making, including enrollment and retention in family planning programs. Conclusions: As Rwanda

  6. A Transformation Similarity Constraint for Groupwise Nonlinear Registration in Longitudinal Neuro Imaging Studies.

    PubMed

    Fleishman, Greg M; Gutman, Boris A; Fletcher, P Thomas; Thompson, Paul

    2015-03-20

    Patients with Alzheimer's disease and other brain disorders often show a similar spatial distribution of volume change throughout the brain over time,(1,2) but this information is not yet used in registration algorithms to refine the quantification of change. Here, we develop a mathematical basis to incorporate that prior information into a longitudinal structural neuroimaging study. We modify the canonical minimization problem for non-linear registration to include a term that couples a collection of registrations together to enforce group similarity. More specifically, throughout the computation we maintain a group-level representation of the transformations and constrain updates to individual transformations to be similar to this representation. The derivations necessary to produce the Euler-Lagrange equations for the coupling term are presented and a gradient descent algorithm based on the formulation was implemented. We demonstrate using 57 longitudinal image pairs from the Alzheimer's Disease Neuroimaging Initiative (ADNI) that longitudinal registration with such a groupwise coupling prior is more robust to noise in estimating change, suggesting such change maps may have several important applications.

  7. A transformation similarity constraint for groupwise nonlinear registration in longitudinal neuroimaging studies

    NASA Astrophysics Data System (ADS)

    Fleishman, Greg M.; Gutman, Boris A.; Fletcher, P. Thomas; Thompson, Paul

    2015-03-01

    Patients with Alzheimer's disease and other brain disorders often show a similar spatial distribution of volume change throughout the brain over time, but this information is not yet used in registration algorithms to refine the quantification of change. Here, we develop a mathematical basis to incorporate that prior information into a longitudinal structural neuroimaging study. We modify the canonical minimization problem for non-linear registration to include a term that couples a collection of registrations together to enforce group similarity. More specifically, throughout the computation we maintain a group-level representation of the transformations and constrain updates to individual transformations to be similar to this representation. The derivations necessary to produce the Euler-Lagrange equations for the coupling term are presented and a gradient descent algorithm based on the formulation was implemented. We demonstrate using 57 longitudinal image pairs from the Alzheimer's Disease Neuroimaging Initiative (ADNI) that longitudinal registration with such a groupwise coupling prior is more robust to noise in estimating change, suggesting such change maps may have several important applications.

  8. Constraints on the first billion years of the geodynamo from paleointensity studies of zircons

    NASA Astrophysics Data System (ADS)

    Tarduno, John; Cottrell, Rory; Davis, William

    2014-05-01

    Several lines of reasoning, including new ideas on core thermal conductivity, suggest that onset of a strong geomagnetic field might have been delayed by one billion years (or more) after the lunar forming event. Here we extend the Proterozoic/Archean to Paleoarchean record of the geomagnetic field constrained by single crystal paleointensity (SCP) analyses (Tarduno et al., Science, 2010) to older times using zircons containing minute magnetic inclusions. Specifically, we focus on samples from the Jack Hills (Yilgarn Craton, Western Australia). We employ a CO2 laser demagnetization system and a small bore (6.3 mm) 3-component DC SQUID magnetometer; the latter offers the highest currently available moment resolution. Sample age is analyzed using SHRIMP U-Pb geochronology. Preliminary data support the presence of a relatively strong Paleoarchean field produced by a core dynamo, extending the known record by at least 100 million years, to approximately 3.55 Ga. These data only serve to exacerbate the apparent problem posed by the presence of a Paleoarchean dynamo. Alternative dynamo driving mechanisms, or efficient core/lowermost mantle heat loss processes unique to the Paleoarchean (and older times) might have been at work. We will discuss these processes, and our efforts to study even older Eoarchean-Hadean zircons.

  9. Rheological constraints on the deformation of Snake River-type ignimbrites: an experimental study

    NASA Astrophysics Data System (ADS)

    Robert, G.; Andrews, G. D.; Whittington, A. G.

    2009-12-01

    We compare the rheology of two members of the Miocene Rogerson Formation (Andrews et al., 2008), Snake River Plain volcanic province, USA. We have studied by parallel-plate viscometry the rheology of two ashfall units associated with the eruption of the lava-like (sensu Branney & Kokelaar, 1992) and rheomorphic Grey’s Landing (GL) ignimbrite (a Snake River-type ignimbrite; Branney et al., 2008) and compared the results to the overlying Sand Springs (SS) ignimbrite. The GL and SS members are similar in whole rock and glass shard chemistry and mineralogy, but differ in crystal content and size fraction, porosity, and texture. Lava-like lithofacies of the GL ignimbrite are either crystallized, devitrified, or perlitized, and do not necessarily represent the original material that came out of the vent to be subsequently deposited, welded and deformed by flow (rheomorphism). We therefore chose to use the fused basal co-ignimbrite ashfall tuff and the upper co-ignimbrite tuff as potential “starting material” for the GL ignimbrite. The two ashfall tuffs and the ignimbrite form a single cooling unit; the tuffs are partly-fused against the bottom and top of the ignimbrite. The basal ash is laminated, moderately porous (~15%), and contains 10-20% crystals; in contrast the upper ash is massive, nearly aphyric, glassy and contains ~5% porosity. The non-rheomorphic SS ignimbrite is separated from the underlying GL ignimbrite by a non-welded ignimbrite and several paleosols. It is a strongly-welded, glassy tuff with a thin non-welded base and no underlying ashfall deposit. The basal ashfall tuff of the GL member and the SS ignimbrite have the same apparent viscosity at 900°C (log η = 10.80 & 10.85 Pa.s, respectively), within the resolution of the parallel-plate apparatus for viscosity. This is in agreement with the results of Lavallée et al. (2008) on a sample of the GL ignimbrite, and suggests that the rheology of those two units is melt-dominated, and is not

  10. A Study of Penalty Function Methods for Constraint Handling with Genetic Algorithm

    NASA Technical Reports Server (NTRS)

    Ortiz, Francisco

    2004-01-01

    is performed in this study. Also, a response surface approach to robust design is used to develop a new penalty function approach. This new penalty function approach is then compared with the other existing penalty functions.

  11. Constraints of opsin structure on the ligand-binding site: studies with ring-fused retinals.

    PubMed

    Hirano, Takahiro; Lim, In Taek; Kim, Don Moon; Zheng, Xiang-Guo; Yoshihara, Kazuo; Oyama, Yoshiaki; Imai, Hiroo; Shichida, Yoshinori; Ishiguro, Masaji

    2002-12-01

    Ring-fused retinal analogs were designed to examine the hula-twist mode of the photoisomerization of the 9-cis retinylidene chromophore. Two 9-cis retinal analogs, the C11-C13 five-membered ring-fused and the C12-C14 five-membered ring-fused retinal derivatives, formed the pigments with opsin. The C11-C13 ring-fused analog was isomerized to a relaxed all-trans chromophore (lambda(max) > 400 nm) at even -269 degrees C and the Schiff base was kept protonated at 0 degrees C. The C12-C14 ring-fused analog was converted photochemically to a bathorhodopsin-like chromophore (lambda(max) = 583 nm) at -196 degrees C, which was further converted to the deprotonated Schiff base at 0 degrees C. The model-building study suggested that the analogs do not form pigments in the retinal-binding site of rhodopsin but form pigments with opsin structures, which have larger binding space generated by the movement of transmembrane helices. The molecular dynamics simulation of the isomerization of the analog chromophores provided a twisted C11-C12 double bond for the C12-C14 ring-fused analog and all relaxed double bonds with a highly twisted C10-C11 bond for the C11-C13 ring-fused analog. The structural model of the C11-C13 ring-fused analog chromophore showed a characteristic flip of the cyclohexenyl moiety toward transmembrane segments 3 and 4. The structural models suggested that hula twist is a primary process for the photoisomerization of the analog chromophores.

  12. Pilot Study of the Efficacy of Constraint-Induced Movement Therapy for Infants and Toddlers with Cerebral Palsy

    PubMed Central

    Lowes, Linda Pax; Mayhan, Marianne; Orr, Teresa; Batterson, Nancy; Tonneman, Jill Alyce; Meyer, Angela; Alfano, Lindsay; Wang, Wei; Whalen, Cara N; Nelin, Mary Ann; Lo, Warren David; Case-Smith, Jane

    2014-01-01

    The evidence for Constraint-Induced Movement Therapy (CIMT) effectiveness for infants and toddlers with unilateral cerebral palsy is minimal. We performed a pilot study of CIMT using one-month usual care, one-month intervention, and one-month maintenance (return to usual care) phases on five infants (7- to 18-month old). For the CIMT phase, the infants received 2 hr of occupational therapy and 1 hr of parent-implemented home program for five days/week. The infants were casted for the rst 23 days, and bimanual therapy was provided for the last three days. Fine motor skills for the more affected arm and gross motor skills improved significantly during the CIMT; these gains were maintained at one-month follow-up. Individual infant data show mixed effects. This pilot study provides initial evidence that CIMT is feasible for infants with unilateral cerebral palsy, and presents preliminary data for CIMT on fine and gross motor performance. PMID:23848499

  13. Morphological constraints in children's spoken language comprehension: a visual world study of plurals inside compounds in English.

    PubMed

    Silva, Renita; Gerth, Sabrina; Clahsen, Harald

    2013-11-01

    Many previous studies have shown that the human language processor is capable of rapidly integrating information from different sources during reading or listening. Yet, little is known about how this ability develops from child to adulthood. To gain insight into how children (in comparison to adults) handle different kinds of linguistic information during on-line language comprehension, the current study investigates a well-known morphological phenomenon that is subject to both structural and semantic constraints, the plurals-in-compounds effect, i.e. the dislike of plural (specifically regular plural) modifiers inside compounds (e.g. rats eater). We examined 96 seven-to-twelve-year-old children and a control group of 32 adults measuring their eye-gaze changes in response to compound-internal plural and singular forms. Our results indicate that children rely more upon structural properties of language (in the present case, morphological cues) early in development and that the ability to efficiently integrate information from multiple sources takes time for children to reach adult-like levels.

  14. [Study on optimal selection of structure of vaneless centrifugal blood pump with constraints on blood perfusion and on blood damage indexes].

    PubMed

    Hu, Zhaoyan; Pan, Youlian; Chen, Zhenglong; Zhang, Tianyi; Lu, Lijun

    2012-12-01

    This paper is aimed to study the optimal selection of structure of vaneless centrifugal blood pump. The optimal objective is determined according to requirements of clinical use. Possible schemes are generally worked out based on structural feature of vaneless centrifugal blood pump. The optimal structure is selected from possible schemes with constraints on blood perfusion and blood damage indexes. Using an optimal selection method one can find the optimum structure scheme from possible schemes effectively. The results of numerical simulation of optimal blood pump showed that the method of constraints of blood perfusion and blood damage is competent for the requirements of selection of the optimal blood pumps.

  15. Mesozoic tectonics of the Arctic: New constraints from provenance studies,Taimyr, Russia

    NASA Astrophysics Data System (ADS)

    Zhang, X.; Pease, V.

    2013-12-01

    Understanding the tectonic development of the Arctic Ocean is important for understanding global tectonics and the framework of petroleum and mineral resources in the Arctic area. The Eurasia and Amerasia basins are the principal physiographic domains of the Arctic Ocean. The Eurasia Basin is known to be the result of slow seafloor spreading; the origin of the Amerasia Basin however remains controversial. Lack of information on the timing, structure, and geochemistry of geological units around the Amerasia Basin limits our ability to understand its development. The Taimyr Peninsula where Mesozoic deformation is well-developed provides a natural laboratory to investigate the tectonic development of the Amerasia Basin. Provenance studies of Taimyr constrain the source areas of Mesozoic sediments in the region and thus identify affinities between them. Detrital zircons from six samples of Triassic and Jurassic sandstone from Southern Taimyr were dated using LA-ICP-MS to test existing models for the opening of the Amerasia Basin. Two Triassic samples present great similarity in detrital zircon population with Triassic sandstone from the paleo-Taimyr river system, including Chukotka, the Wrangel Island and the New Siberian Islands. These samples all contain Permo-Triassic (236 - 250 Ma), Permo-Carboniferous (260 - 330 Ma), Devonian (340 - 390 Ma) late Precambrian-Silurian (420 - 580 Ma) and Neoproterozoic (620 - 1000 Ma) zircons. These detrital zircon ages suggest Triassic sediments in these locations may have been derived from Siberia Trap, Taimyr and the Ural Mountains of Arctic Russia. It is therefore likely that Taimyr, Chukotka, the Wrangel Island and the New Siberian Islands which are separated at present were close to each other or belonged to the same large drainage system before the opening of the Amerasia Basin. Two Middle Jurassic samples and two Upper Jurassic samples from Taimyr have dominant Permo-Triassic peaks (246 - 260 Ma) suggesting a proximal source

  16. Constraints on planetary formation from the discovery & study of transiting Extrasolar Planets

    NASA Astrophysics Data System (ADS)

    Triaud, A. H. M. J.

    2011-08-01

    Earth-Sun distance. In Astronomy, we cannot do experiments; we are a part of it. Instead, we search and characterise several similar objects in order to extract information out of them statistically. To answer our question, we needed to find several objects and detect the clues from their past history bringing us back to the processes that led to their formation. There are several manners with which one can find planets. For this thesis, the so-called transit method was used. It consists in detecting a periodic loss of light from a star in front of which a planet passes: a transit. This method is particularly sensitive to the presence of hot Jupiters. During this thesis, about fifty planets of such type have been discovered, about a third of the known hot Jupiters. Those planets are confirmed thanks to radial velocity measurements, the same technique that led to the discovery of the first extrasolar planet, around the star 51 Pegasi. The analysis of the stellar light affected by the presence of a planet around it, notably the light received during transit, allows us to know about the mass, the size of the planet, its orbital period, the shape of its orbit, its temperature, even the chemical composition of its atmosphere. Furthermore, these observations give us the occasion to study the star around which is found the planet, such as its mass, its size, its rotation speed, as well as give estimates on its age. One type of observations was employed in particular: the Rossiter-McLaughlin effect. During transit, this effect creates an anomaly compared to the expected radial velocities. Through a modelisation of this anomaly, it is possible to measure the projection of the angle between the orbital plane of the planet and the equatorial plane of the star, on the sky. In our System, all planets are located more or less in a same plane : the ecliptic. The equatorial plane of the Sun is also almost aligned with the ecliptic. This observation led Kant and Laplace to postulate on

  17. Data reporting constraints for the lymphatic filariasis mass drug administration activities in two districts in Ghana: A qualitative study

    PubMed Central

    Aryeetey, Richmond; Boateng, Richard; Anto, Francis; Aikins, Moses; Gyapong, Margaret; Gyapong, John

    2015-01-01

    Objectives: Timely and accurate health data are important for objective decision making and policy formulation. However, little evidence exists to explain why poor quality routine health data persist. This study examined the constraints to data reporting for the lymphatic filariasis mass drug administration programme in two districts in Ghana. This qualitative study focused on timeliness and accuracy of mass drug administration reports submitted by community health volunteers. Methods: The study is nested within a larger study focusing on the feasibility of mobile phone technology for the lymphatic filariasis programme. Using an exploratory study design, data were obtained through in-depth interviews (n = 7) with programme supervisors and focus group discussions (n = 4) with community health volunteers. Results were analysed using thematic content analysis. Results: Reasons for delays in reporting were attributed to poor numeracy skills among community health volunteers, difficult physical access to communities, high supervisor workload, poor adherence reporting deadlines, difficulty in reaching communities within allocated time and untimely release of programme funds. Poor accuracy of data was mainly attributed to inadequate motivation for community health volunteers and difficulty calculating summaries. Conclusion: This study has shown that there are relevant issues that need to be addressed in order to improve the quality of lymphatic filariasis treatment coverage reports. Some of the factors identified are problems within the health system; others are specific to the community health volunteers and the lymphatic filariasis programme. Steps such as training on data reporting should be intensified for community health volunteers, allowances for community health volunteers should be re-evaluated and other non-monetary incentives should be provided for community health volunteers. PMID:26770791

  18. Convergence, adaptation, and constraint.

    PubMed

    Losos, Jonathan B

    2011-07-01

    Convergent evolution of similar phenotypic features in similar environmental contexts has long been taken as evidence of adaptation. Nonetheless, recent conceptual and empirical developments in many fields have led to a proliferation of ideas about the relationship between convergence and adaptation. Despite criticism from some systematically minded biologists, I reaffirm that convergence in taxa occupying similar selective environments often is the result of natural selection. However, convergent evolution of a trait in a particular environment can occur for reasons other than selection on that trait in that environment, and species can respond to similar selective pressures by evolving nonconvergent adaptations. For these reasons, studies of convergence should be coupled with other methods-such as direct measurements of selection or investigations of the functional correlates of trait evolution-to test hypotheses of adaptation. The independent acquisition of similar phenotypes by the same genetic or developmental pathway has been suggested as evidence of constraints on adaptation, a view widely repeated as genomic studies have documented phenotypic convergence resulting from change in the same genes, sometimes even by the same mutation. Contrary to some claims, convergence by changes in the same genes is not necessarily evidence of constraint, but rather suggests hypotheses that can test the relative roles of constraint and selection in directing phenotypic evolution. © 2011 The Author(s). Evolution© 2011 The Society for the Study of Evolution.

  19. Groundbreaking constraints on emissions from GEO-CAPE: case studies of CH4, NH3, SO2 and NO2

    NASA Astrophysics Data System (ADS)

    Jeong, G.; Bash, J. O.; Cady-Pereira, K. E.; Henze, D. K.; Cohen, R. C.; Krotkov, N. A.; Lamsal, L.; Li, C.; Wecht, K.; Worden, J.; Worden, H. M.; Perkins, A.

    2012-12-01

    While existing remote sensing measurements currently provide valuable sources of top-down constraints on a wide range of emissions of air pollutants and greenhouse gases, geostationary observations hold the potential to significantly advance our scientific understanding of constituent sources in several ways. Over North America, the proposed GEO-CAPE instrument will allow replacement of monthly mean and annual average estimates of emissions, ones that are tuned to current and/or historical observations, with detailed mechanistic models that are capable of projecting outside the envelope of current observations. GEO-CAPE observations are expected to be a major leap forward in observations that can test and constrain such models. In this manner, GEO-CAPE will also allow development of high space and time resolution emission fields that will enable detailed evaluation of other components of a chemical transport model (e.g. boundary layer fluid dynamics). Here we present case studies of the expected benefits of GEO-CAPE observations for constraining bi-directional fluxes of ammonia, the sources and chemical evolution of NOx, the lifetime of SO2, and the emissions of CH4 from anthropogenic vs natural sources. In each case, we illustrate the ways in which geostationary observations provide insight beyond current capabilities with low earth orbit satellites.

  20. Study of space shuttle EVA/IVA support requirements. Volume 2: EVA/IVA tasks, guidelines, and constraints definition

    NASA Technical Reports Server (NTRS)

    Webbon, B. W.; Copeland, R. J.; Wood, P. W., Jr.; Cox, R. L.

    1973-01-01

    The guidelines for EVA and IVA tasks to be performed on the space shuttle are defined. In deriving tasks, guidelines, and constraints, payloads were first identified from the mission model. Payload requirements, together with man and manipulator capabilities, vehicle characteristics and operation, and safety considerations led to a definition of candidate tasks. Guidelines and constraints were also established from these considerations. Scenarios were established, and screening criteria, such as commonality of EVA and IVA activities, were applied to derive representative planned and unplanned tasks. The whole spectrum of credible contingency situations with a potential requirement for EVA/IVA was analyzed.

  1. Weighted constraints in generative linguistics.

    PubMed

    Pater, Joe

    2009-08-01

    Harmonic Grammar (HG) and Optimality Theory (OT) are closely related formal frameworks for the study of language. In both, the structure of a given language is determined by the relative strengths of a set of constraints. They differ in how these strengths are represented: as numerical weights (HG) or as ranks (OT). Weighted constraints have advantages for the construction of accounts of language learning and other cognitive processes, partly because they allow for the adaptation of connectionist and statistical models. HG has been little studied in generative linguistics, however, largely due to influential claims that weighted constraints make incorrect predictions about the typology of natural languages, predictions that are not shared by the more popular OT. This paper makes the case that HG is in fact a promising framework for typological research, and reviews and extends the existing arguments for weighted over ranked constraints.

  2. Solution conformational study of Scyliorhinin I analogues with conformational constraints by two-dimensional NMR and theoretical conformational analysis.

    PubMed

    Rodziewicz-Motowidło, S; Legowska, A; Qi, X F; Czaplewski, C; Liwo, A; Sowiński, P; Mozga, W; Olczak, J; Zabrocki, J; Rolka, K

    2000-09-01

    Two analogues of Scyliorhinin I (Scyl), a tachykinin with N-MeLeu in position 8 and a 1,5-disubstituted tetrazole ring between positions 7 and 8, introduced in order to generate local conformational constraints, were synthesized using the solid-phase method. Conformational studies in water and DMSO-d6 were performed on these peptides using a combination of the two-dimensional NMR technique and theoretical conformational analysis. The algorithm of conformational search consisted of the following three stages: (i) extensive global conformational analysis in order to find all low-energy conformations; (ii) calculation of the NOE effects and vicinal coupling constants for each of the low energy conformations; (iii) determining the statistical weights of these conformations by means of a nonlinear least-squares procedure, in order to obtain the best fit of the averaged simulated spectrum to the experimental one. In both solvents the three-dimensional structure of the analogues studied can be interpreted only in terms of an ensemble of multiple conformations. For [MeLeu8]Scyl, the C-terminal 6-10 fragment adopts more rigid structure than the N-terminal one. In the case of the analogue with the tetrazole ring in DMSO-d6 the three-dimensional structure is characterized by two dominant conformers with similar geometry of their backbones. They superimpose especially well (RMSD = 0.28 A) in the 6-9 fragments. All conformers calculated in both solvents superimpose in their C-terminal fragments much better than those of the first analogue. The results obtained indicate that the introduction of the tetrazole ring into the Scyl molecule rigidifies its structure significantly more than that of MeLeu.

  3. Constraint monitoring in TOSCA

    NASA Technical Reports Server (NTRS)

    Beck, Howard

    1992-01-01

    The Job-Shop Scheduling Problem (JSSP) deals with the allocation of resources over time to factory operations. Allocations are subject to various constraints (e.g., production precedence relationships, factory capacity constraints, and limits on the allowable number of machine setups) which must be satisfied for a schedule to be valid. The identification of constraint violations and the monitoring of constraint threats plays a vital role in schedule generation in terms of the following: (1) directing the scheduling process; and (2) informing scheduling decisions. This paper describes a general mechanism for identifying constraint violations and monitoring threats to the satisfaction of constraints throughout schedule generation.

  4. Constraint-Induced Aphasia Therapy in the Acute Stage: What Is the Key Factor for Efficacy? A Randomized Controlled Study.

    PubMed

    Woldag, Hartwig; Voigt, Nancy; Bley, Maria; Hummelsheim, Horst

    2017-01-01

    Constraint-induced aphasia therapy (CIAT) has proven effective in patients with subacute and chronic forms of aphasia. It has remained unclear, however, whether intensity of therapy or constraint is the relevant factor. Data about intensive speech and language therapy (SLT) are conflicting. To identify the effective component of CIAT and assess the feasibility of SLT in the acute stage after stroke. A total of 60 patients with aphasia (68.2 ± 11.7 years) were enrolled 18.9 days after first-ever stroke. They were randomly distributed into 3 groups: (1) CIAT group receiving therapy for 3 hours per day (10 workdays, total 30 hours); (2) conventional communication treatment group, with same intensity without constraints; and (3) control group receiving individual therapy twice a day as well as group therapy (total 14 hours). Patients were assessed pretreatment and posttreatment using the Aachener Aphasia Test (primary end point: token test) and the Communicative Activity Log (CAL). Pretreatment, there were no between-group differences. Posttreatment, all groups showed significant improvements without between-group differences. It was found that 14 hours of aphasia therapy administered within 2 weeks as individual therapy, focusing on individual deficits, combined with group sessions has proven to be most efficient. This approach yielded the same outcome as 30 hours of group therapy, either in the form of CIAT or group therapy without constraints. SLT in an intensive treatment schedule is feasible and was well tolerated in the acute stage after stroke. © The Author(s) 2016.

  5. "Big Brown Dog" or "Brown Big Dog?" An Electrophysiological Study of Semantic Constraints on Prenominal Adjective Order

    ERIC Educational Resources Information Center

    Kemmerer, David; Weber-Fox, Christine; Price, Karen; Zdanczyk, Cynthia; Way, Heather

    2007-01-01

    Event-related brain potentials (ERPs) were recorded while participants read and made acceptability judgments about sentences containing three types of adjective sequences: (1) normal sequences--e.g., "Jennifer rode a huge gray elephant"; (2) reversed sequences that violate grammatical-semantic constraints on linear order--e.g., *"Jennifer rode a…

  6. The Role of Architectural and Learning Constraints in Neural Network Models: A Case Study on Visual Space Coding.

    PubMed

    Testolin, Alberto; De Filippo De Grazia, Michele; Zorzi, Marco

    2017-01-01

    The recent "deep learning revolution" in artificial neural networks had strong impact and widespread deployment for engineering applications, but the use of deep learning for neurocomputational modeling has been so far limited. In this article we argue that unsupervised deep learning represents an important step forward for improving neurocomputational models of perception and cognition, because it emphasizes the role of generative learning as opposed to discriminative (supervised) learning. As a case study, we present a series of simulations investigating the emergence of neural coding of visual space for sensorimotor transformations. We compare different network architectures commonly used as building blocks for unsupervised deep learning by systematically testing the type of receptive fields and gain modulation developed by the hidden neurons. In particular, we compare Restricted Boltzmann Machines (RBMs), which are stochastic, generative networks with bidirectional connections trained using contrastive divergence, with autoencoders, which are deterministic networks trained using error backpropagation. For both learning architectures we also explore the role of sparse coding, which has been identified as a fundamental principle of neural computation. The unsupervised models are then compared with supervised, feed-forward networks that learn an explicit mapping between different spatial reference frames. Our simulations show that both architectural and learning constraints strongly influenced the emergent coding of visual space in terms of distribution of tuning functions at the level of single neurons. Unsupervised models, and particularly RBMs, were found to more closely adhere to neurophysiological data from single-cell recordings in the primate parietal cortex. These results provide new insights into how basic properties of artificial neural networks might be relevant for modeling neural information processing in biological systems.

  7. The Role of Architectural and Learning Constraints in Neural Network Models: A Case Study on Visual Space Coding

    PubMed Central

    Testolin, Alberto; De Filippo De Grazia, Michele; Zorzi, Marco

    2017-01-01

    The recent “deep learning revolution” in artificial neural networks had strong impact and widespread deployment for engineering applications, but the use of deep learning for neurocomputational modeling has been so far limited. In this article we argue that unsupervised deep learning represents an important step forward for improving neurocomputational models of perception and cognition, because it emphasizes the role of generative learning as opposed to discriminative (supervised) learning. As a case study, we present a series of simulations investigating the emergence of neural coding of visual space for sensorimotor transformations. We compare different network architectures commonly used as building blocks for unsupervised deep learning by systematically testing the type of receptive fields and gain modulation developed by the hidden neurons. In particular, we compare Restricted Boltzmann Machines (RBMs), which are stochastic, generative networks with bidirectional connections trained using contrastive divergence, with autoencoders, which are deterministic networks trained using error backpropagation. For both learning architectures we also explore the role of sparse coding, which has been identified as a fundamental principle of neural computation. The unsupervised models are then compared with supervised, feed-forward networks that learn an explicit mapping between different spatial reference frames. Our simulations show that both architectural and learning constraints strongly influenced the emergent coding of visual space in terms of distribution of tuning functions at the level of single neurons. Unsupervised models, and particularly RBMs, were found to more closely adhere to neurophysiological data from single-cell recordings in the primate parietal cortex. These results provide new insights into how basic properties of artificial neural networks might be relevant for modeling neural information processing in biological systems. PMID:28377709

  8. Small pelagic fish reproductive strategies in upwelling systems: A natal homing evolutionary model to study environmental constraints

    NASA Astrophysics Data System (ADS)

    Brochier, T.; Colas, F.; Lett, C.; Echevin, V.; Cubillos, L. A.; Tam, J.; Chlaida, M.; Mullon, C.; Fréon, P.

    2009-12-01

    Although little is known about the individual-level mechanisms that influence small pelagic fish species’ reproductive strategy, Mullon et al. [Mullon, C., Cury, P., Penven, P., 2002. Evolutionary individual-based model for the recruitment of anchovy ( Engraulis capensis) in the southern Benguela. Canadian Journal of Fisheries and Aquatic Sciences 59, 910-922] showed that the observed anchovy spawning patterns in the southern Benguela Current system off South Africa could be accurately reproduced by simulating a natal homing reproductive strategy, i.e. individuals spawning at their natal date and place. Here we used a similar method, i.e., an individual-based model of the natal homing reproductive strategy, and applied it to other upwelling systems: the northern Humboldt Current system off Peru, the southern Humboldt Current system off Chile and the central Canary Current system off Morocco. We investigated the spatial (horizontal and vertical) and seasonal spawning patterns that emerged after applying different environmental constraints in the model, and compared these to observed spawning patterns of sardine and anchovy in their respective systems. The selective environmental constraints tested were: (1) lethal temperature; (2) retention over the continental shelf; and (3) avoidance of dispersive structures. Simulated horizontal spatial patterns and seasonal patterns compared reasonably well with field data, but vertical patterns in most cases did not. Similarly to what was found for the southern Benguela, temperature was a determinant constraint in the southern Humboldt. The shelf retention constraint led to selection of a particular spawning season during the period of minimum upwelling in all three of the upwelling regions considered, and to spatial patterns that matched observed anchovy spawning off Chile and sardine spawning off Morocco. The third constraint, avoidance of dispersive structures, led to the emergence of a spawning season during the period of

  9. Extended X-ray Absorption Fine Structure Study of Bond Constraints in Ge-Sb-Te Alloys

    DTIC Science & Technology

    2011-02-07

    matrix. BCT argues that low coordination results in a floppy material that would allow for easy glass formation but the steric freedom of such a...exists in a so-called intermediate phase of ideal constraints. Material in this regime should be good glass formers and may exhibit reversible photo- or...good glass - former with an ability to make rapid and reversible transitions between the amorphous and crystalline phases. The ideal nature of

  10. Measuring the Statutory and Regulatory Constraints on DoD Acquisition: Research Design for an Empirical Study

    DTIC Science & Technology

    2006-01-01

    processes that some of the 12 Section 800 refers to the section of the FY 1991 National Defense Authorization Act containing language establishing the... Aquisition sumably, such compliance activities would not account for 100 percent of an individual staff member’s time, except perhaps in certain...Regulatory Constraints on DoD Aquisition compliance activities required by a given statute or regulation.2 Within each area, we decided to include a category

  11. A Brownian dynamics study on ferrofluid colloidal dispersions using an iterative constraint method to satisfy Maxwell’s equations

    SciTech Connect

    Dubina, Sean Hyun Wedgewood, Lewis Edward

    2016-07-15

    Ferrofluids are often favored for their ability to be remotely positioned via external magnetic fields. The behavior of particles in ferromagnetic clusters under uniformly applied magnetic fields has been computationally simulated using the Brownian dynamics, Stokesian dynamics, and Monte Carlo methods. However, few methods have been established that effectively handle the basic principles of magnetic materials, namely, Maxwell’s equations. An iterative constraint method was developed to satisfy Maxwell’s equations when a uniform magnetic field is imposed on ferrofluids in a heterogeneous Brownian dynamics simulation that examines the impact of ferromagnetic clusters in a mesoscale particle collection. This was accomplished by allowing a particulate system in a simple shear flow to advance by a time step under a uniformly applied magnetic field, then adjusting the ferroparticles via an iterative constraint method applied over sub-volume length scales until Maxwell’s equations were satisfied. The resultant ferrofluid model with constraints demonstrates that the magnetoviscosity contribution is not as substantial when compared to homogeneous simulations that assume the material’s magnetism is a direct response to the external magnetic field. This was detected across varying intensities of particle-particle interaction, Brownian motion, and shear flow. Ferroparticle aggregation was still extensively present but less so than typically observed.

  12. Modified constraint induced movement therapy enhanced by a neuro-development treatment-based therapeutic handling protocol: two case studies.

    PubMed

    Haynes, Marjorie Prim; Phillips, Dawn

    2012-01-01

    Modified Constraint Induced Movement Therapy (CIMT) and Neuro-Developmental Treatment (NDT) are both intervention strategies that focus on active practice to optimize function. CIMT involves constraint of the less involved upper extremity during function and NDT includes facilitation of optimal postural control and symmetry to enhance the ability to complete a given motor function. The purpose of this article is to describe an intervention protocol for children with hemiplegia that integrates key NDT and CIMT principles. Two children participated in a modified CIMT (mCIMT)/NDT program 2 hours a day for two months. The children wore a constraint on the less involved arm and participated in guided play with early intervention members and parents. Play was individualized to developmental level and incorporated principles of NDT. Function was measured pre- and post-intervention using the PDMS-2, QUEST, ACQUIRE Therapy Motor Patterns, and ACQUIRE Functional Activities. Both children demonstrated motor skill acquisition, improved quality of functional use, and increased frequency of bilateral hand use. Parents found the protocol challenging but manageable in their daily routines. The inclusion of NDT principles within a mCIMT protocol may be an effective intervention to maximize functional motor skill acquisition in children with hemiplegia. Additional research is warranted to support this intervention.

  13. A Brownian dynamics study on ferrofluid colloidal dispersions using an iterative constraint method to satisfy Maxwell's equations

    NASA Astrophysics Data System (ADS)

    Dubina, Sean Hyun; Wedgewood, Lewis Edward

    2016-07-01

    Ferrofluids are often favored for their ability to be remotely positioned via external magnetic fields. The behavior of particles in ferromagnetic clusters under uniformly applied magnetic fields has been computationally simulated using the Brownian dynamics, Stokesian dynamics, and Monte Carlo methods. However, few methods have been established that effectively handle the basic principles of magnetic materials, namely, Maxwell's equations. An iterative constraint method was developed to satisfy Maxwell's equations when a uniform magnetic field is imposed on ferrofluids in a heterogeneous Brownian dynamics simulation that examines the impact of ferromagnetic clusters in a mesoscale particle collection. This was accomplished by allowing a particulate system in a simple shear flow to advance by a time step under a uniformly applied magnetic field, then adjusting the ferroparticles via an iterative constraint method applied over sub-volume length scales until Maxwell's equations were satisfied. The resultant ferrofluid model with constraints demonstrates that the magnetoviscosity contribution is not as substantial when compared to homogeneous simulations that assume the material's magnetism is a direct response to the external magnetic field. This was detected across varying intensities of particle-particle interaction, Brownian motion, and shear flow. Ferroparticle aggregation was still extensively present but less so than typically observed.

  14. Asteroseismic constraints for Gaia

    NASA Astrophysics Data System (ADS)

    Creevey, O. L.; Thévenin, F.

    2012-12-01

    Distances from the Gaia mission will no doubt improve our understanding of stellar physics by providing an excellent constraint on the luminosity of the star. However, it is also clear that high precision stellar properties from, for example, asteroseismology, will also provide a needed input constraint in order to calibrate the methods that Gaia will use, e.g. stellar models or GSP_Phot. For solar-like stars (F, G, K IV/V), asteroseismic data delivers at the least two very important quantities: (1) the average large frequency separation < Δ ν > and (2) the frequency corresponding to the maximum of the modulated-amplitude spectrum ν_{max}. Both of these quantities are related directly to stellar parameters (radius and mass) and in particular their combination (gravity and density). We show how the precision in < Δ ν >, ν_{max}, and atmospheric parameters T_{eff} and [Fe/H] affect the determination of gravity (log g) for a sample of well-known stars. We find that log g can be determined within less than 0.02 dex accuracy for our sample while considering precisions in the data expected for V˜12 stars from Kepler data. We also derive masses and radii which are accurate to within 1σ of the accepted values. This study validates the subsequent use of all of the available asteroseismic data on solar-like stars from the Kepler field (>500 IV/V stars) in order to provide a very important constraint for Gaia calibration of GSP_Phot} through the use of log g. We note that while we concentrate on IV/V stars, both the CoRoT and Kepler fields contain asteroseismic data on thousands of giant stars which will also provide useful calibration measures.

  15. Multisite trial on efficacy of constraint-induced movement therapy in children with hemiplegia: study design and methodology.

    PubMed

    Facchin, Paola; Rosa-Rizzotto, Melissa; Turconi, Anna Carla; Pagliano, Emanuela; Fazzi, Elisa; Stortini, Massimo; Fedrizzi, Ermellina

    2009-03-01

    In the past decades, several treatment approaches have been used to improve upper limb function in hemiplegic cerebral palsy. Only recently has constraint-induced movement therapy emerged as a treatment approach for children with hemiplegic cerebral palsy with the aim of reversing the behavioral suppression of movement in the affected upper limb. To date, evidence on this treatment has been very poor and limited, because all currently available trials reveal methodological limitations and a need for additional research to support the application of this treatment technique. This article presents the methodological choices, design, and main characteristics of an ongoing controlled clinical trial on the effectiveness and safety of constraint-induced movement therapy combined with an intensive rehabilitation program and compared with two comparison groups: one treated with an intensive rehabilitation program and the other with standard treatment. Twenty-one rehabilitation sites are currently recruiting patients with hemiplegic cerebral palsy, aged between 2 and 8 yrs, who have never undergone constraint therapy. Primary outcome measures include two major domains: upper limb motor ability (Quality of Upper Extremity Skills Test) and hand function assessment evaluating both grip function and spontaneous use of the affected side (Besta scale). Secondary outcome measures concern overall function, behavior, compliance, and satisfaction with treatment program of both child and family. Patients' follow-up is of 12 mos after treatment. Research in children has always been neglected in comparison with adults, because of ethical reasons regarding the use of children for experimental purposes. The consequence has been the utilization of treatment and assessment tools and techniques that have not always been tested in pediatric patients or evidence is very scarce. Discussing and working on pediatric research methods represents an urgent need in rehabilitation research.

  16. Do constraints associated with the locomotor habitat drive the evolution of forelimb shape? A case study in musteloid carnivorans.

    PubMed

    Fabre, Anne-Claire; Cornette, Raphael; Goswami, Anjali; Peigné, Stéphane

    2015-06-01

    Convergence in morphology can result from evolutionary adaptations in species living in environments with similar selective pressures. Here, we investigate whether the shape of the forelimb long bones has converged in environments imposing similar functional constraints, using musteloid carnivores as a model. The limbs of quadrupeds are subjected to many factors that may influence their shape. They need to support body mass without collapsing or breaking, yet at the same time resist the stresses and strains induced by locomotion. This likely imposes strong constraints on their morphology. Our geometric morphometric analyses show that locomotion, body mass and phylogeny all influence the shape of the forelimb. Furthermore, we find a remarkable convergence between: (i) aquatic and semi-fossorial species, both displaying a robust forelimb, with a shape that improves stability and load transfer in response to the physical resistance imposed by the locomotor environment; and (ii) aquatic and arboreal/semi-arboreal species, with both groups displaying a broad capitulum. This augments the degree of pronation/supination, an important feature for climbing as well as grasping and manipulation ability, behaviors common to aquatic and arboreal species. In summary, our results highlight how musteloids with different locomotor ecologies show differences in the anatomy of their forelimb bones. Yet, functional demands for limb movement through dense media also result in convergence in forelimb long-bone shape between diverse groups, for example, otters and badgers.

  17. Study of Welding Distortion and Residual Stress Considering Nonlinear Yield Stress Curves and Multi-constraint Equations

    NASA Astrophysics Data System (ADS)

    Rong, Youmin; Zhang, Guojun; Huang, Yu

    2016-10-01

    Inherent strain analysis has been successfully applied to predict welding deformations of large-scale structural components, while thermal-elastic-plastic finite element method is rarely used for its disadvantages of long calculation period and large storage space. In this paper, a hybrid model considering nonlinear yield stress curves and multi-constraint equations to thermal-elastic-plastic analysis is further proposed to predict welding distortions and residual stresses of large-scale structures. For welding T-joint structural steel S355JR by metal active gas welding, the published experiment results of temperature and displacement fields are applied to illustrate the credibility of the proposed integration model. By comparing numerical results of four different cases with the experiment results, it is verified that prediction precision of welding deformations and residual stresses is apparently improved considering the power-law hardening model, and computational time is also obviously shortened about 30.14% using multi-constraint equations. On the whole, the proposed hybrid method can be further used to precisely and efficiently predict welding deformations and residual stresses of large-scale structures.

  18. Do constraints associated with the locomotor habitat drive the evolution of forelimb shape? A case study in musteloid carnivorans

    PubMed Central

    Fabre, Anne-Claire; Cornette, Raphael; Goswami, Anjali; Peigné, Stéphane

    2015-01-01

    Convergence in morphology can result from evolutionary adaptations in species living in environments with similar selective pressures. Here, we investigate whether the shape of the forelimb long bones has converged in environments imposing similar functional constraints, using musteloid carnivores as a model. The limbs of quadrupeds are subjected to many factors that may influence their shape. They need to support body mass without collapsing or breaking, yet at the same time resist the stresses and strains induced by locomotion. This likely imposes strong constraints on their morphology. Our geometric morphometric analyses show that locomotion, body mass and phylogeny all influence the shape of the forelimb. Furthermore, we find a remarkable convergence between: (i) aquatic and semi-fossorial species, both displaying a robust forelimb, with a shape that improves stability and load transfer in response to the physical resistance imposed by the locomotor environment; and (ii) aquatic and arboreal/semi-arboreal species, with both groups displaying a broad capitulum. This augments the degree of pronation/supination, an important feature for climbing as well as grasping and manipulation ability, behaviors common to aquatic and arboreal species. In summary, our results highlight how musteloids with different locomotor ecologies show differences in the anatomy of their forelimb bones. Yet, functional demands for limb movement through dense media also result in convergence in forelimb long-bone shape between diverse groups, for example, otters and badgers. PMID:25994128

  19. Individualized Radical Radiotherapy of Non-Small-Cell Lung Cancer Based on Normal Tissue Dose Constraints: A Feasibility Study

    SciTech Connect

    Baardwijk, Angela van Bosmans, Geert; Boersma, Liesbeth; Wanders, Stofferinus; Dekker, Andre; Dingemans, Anne Marie C.; Bootsma, Gerben; Geraedts, Wiel; Pitz, Cordula; Simons, Jean; Lambin, Philippe; Ruysscher, Dirk de

    2008-08-01

    Purpose: Local recurrence is a major problem after (chemo-)radiation for non-small-cell lung cancer. We hypothesized that for each individual patient, the highest therapeutic ratio could be achieved by increasing total tumor dose (TTD) to the limits of normal tissues, delivered within 5 weeks. We report first results of a prospective feasibility trial. Methods and Materials: Twenty-eight patients with medically inoperable or locally advanced non-small-cell lung cancer, World Health Organization performance score of 0-1, and reasonable lung function (forced expiratory volume in 1 second > 50%) were analyzed. All patients underwent irradiation using an individualized prescribed TTD based on normal tissue dose constraints (mean lung dose, 19 Gy; maximal spinal cord dose, 54 Gy) up to a maximal TTD of 79.2 Gy in 1.8-Gy fractions twice daily. No concurrent chemoradiation was administered. Toxicity was scored using the Common Terminology Criteria for Adverse Events criteria. An {sup 18}F-fluoro-2-deoxy-glucose-positron emission tomography-computed tomography scan was performed to evaluate (metabolic) response 3 months after treatment. Results: Mean delivered dose was 63.0 {+-} 9.8 Gy. The TTD was most often limited by the mean lung dose (32.1%) or spinal cord (28.6%). Acute toxicity generally was mild; only 1 patient experienced Grade 3 cough and 1 patient experienced Grade 3 dysphagia. One patient (3.6%) died of pneumonitis. For late toxicity, 2 patients (7.7%) had Grade 3 cough or dyspnea; none had severe dysphagia. Complete metabolic response was obtained in 44% (11 of 26 patients). With a median follow-up of 13 months, median overall survival was 19.6 months, with a 1-year survival rate of 57.1%. Conclusions: Individualized maximal tolerable dose irradiation based on normal tissue dose constraints is feasible, and initial results are promising.

  20. On Random Betweenness Constraints

    NASA Astrophysics Data System (ADS)

    Goerdt, Andreas

    Ordering constraints are analogous to instances of the satisfiability problem in conjunctive normalform, but instead of a boolean assignment we consider a linear ordering of the variables in question. A clause becomes true given a linear ordering iff the relative ordering of its variables obeys the constraint considered.

  1. Creating Positive Task Constraints

    ERIC Educational Resources Information Center

    Mally, Kristi K.

    2006-01-01

    Constraints are characteristics of the individual, the task, or the environment that mold and shape movement choices and performances. Constraints can be positive--encouraging proficient movements or negative--discouraging movement or promoting ineffective movements. Physical educators must analyze, evaluate, and determine the effect various…

  2. Creating Positive Task Constraints

    ERIC Educational Resources Information Center

    Mally, Kristi K.

    2006-01-01

    Constraints are characteristics of the individual, the task, or the environment that mold and shape movement choices and performances. Constraints can be positive--encouraging proficient movements or negative--discouraging movement or promoting ineffective movements. Physical educators must analyze, evaluate, and determine the effect various…

  3. Constraint Reasoning Over Strings

    NASA Technical Reports Server (NTRS)

    Koga, Dennis (Technical Monitor); Golden, Keith; Pang, Wanlin

    2003-01-01

    This paper discusses an approach to representing and reasoning about constraints over strings. We discuss how many string domains can often be concisely represented using regular languages, and how constraints over strings, and domain operations on sets of strings, can be carried out using this representation.

  4. Bilateral brain reorganization with memantine and constraint-induced aphasia therapy in chronic post-stroke aphasia: An ERP study.

    PubMed

    Barbancho, Miguel A; Berthier, Marcelo L; Navas-Sánchez, Patricia; Dávila, Guadalupe; Green-Heredia, Cristina; García-Alberca, José M; Ruiz-Cruces, Rafael; López-González, Manuel V; Dawid-Milner, Marc S; Pulvermüller, Friedemann; Lara, J Pablo

    2015-01-01

    Changes in ERP (P100 and N400) and root mean square (RMS) were obtained during a silent reading task in 28 patients with chronic post-stroke aphasia in a randomized, double-blind, placebo-controlled trial of both memantine and constraint-induced aphasia therapy (CIAT). Participants received memantine/placebo alone (weeks 0-16), followed by drug treatment combined with CIAT (weeks 16-18), and then memantine/placebo alone (weeks 18-20). ERP/RMS values (week 16) decreased more in the memantine group than in the placebo group. During CIAT application (weeks 16-18), improvements in aphasia severity and ERP/RMS values were amplified by memantine and changes remained stable thereafter (weeks 18-20). Changes in ERP/RMS occurred in left and right hemispheres and correlated with gains in language performance. No changes in ERP/RMS were found in a healthy group in two separated evaluations. Our results show that aphasia recovery induced by both memantine alone and in combination with CIAT is indexed by bilateral cortical potentials.

  5. Dynamic Constraints Networks

    DTIC Science & Technology

    1989-10-31

    static approach to constrained networks has been used to develop a dynamic theory of constraint networks for problem solving. The scientific results of this development resulted in six scientific publications . (KT)

  6. Temporal Constraint Reasoning With Preferences

    NASA Technical Reports Server (NTRS)

    Khatib, Lina; Morris, Paul; Morris, Robert; Rossi, Francesca

    2001-01-01

    A number of reasoning problems involving the manipulation of temporal information can naturally be viewed as implicitly inducing an ordering of potential local decisions involving time (specifically, associated with durations or orderings of events) on the basis of preferences. For example. a pair of events might be constrained to occur in a certain order, and, in addition. it might be preferable that the delay between them be as large, or as small, as possible. This paper explores problems in which a set of temporal constraints is specified, where each constraint is associated with preference criteria for making local decisions about the events involved in the constraint, and a reasoner must infer a complete solution to the problem such that, to the extent possible, these local preferences are met in the best way. A constraint framework for reasoning about time is generalized to allow for preferences over event distances and durations, and we study the complexity of solving problems in the resulting formalism. It is shown that while in general such problems are NP-hard, some restrictions on the shape of the preference functions, and on the structure of the preference set, can be enforced to achieve tractability. In these cases, a simple generalization of a single-source shortest path algorithm can be used to compute a globally preferred solution in polynomial time.

  7. Allocating limited resources in a time of fiscal constraints: a priority setting case study from Dalhousie University Faculty of Medicine.

    PubMed

    Mitton, Craig; Levy, Adrian; Gorsky, Diane; MacNeil, Christina; Dionne, Francois; Marrie, Tom

    2013-07-01

    Facing a projected $1.4M deficit on a $35M operating budget for fiscal year 2011/2012, members of the Dalhousie University Faculty of Medicine developed and implemented an explicit, transparent, criteria-based priority setting process for resource reallocation. A task group that included representatives from across the Faculty of Medicine used a program budgeting and marginal analysis (PBMA) framework, which provided an alternative to the typical public-sector approaches to addressing a budget deficit of across-the-board spending cuts and political negotiation. Key steps to the PBMA process included training staff members and department heads on priority setting and resource reallocation, establishing process guidelines to meet immediate and longer-term fiscal needs, developing a reporting structure and forming key working groups, creating assessment criteria to guide resource reallocation decisions, assessing disinvestment proposals from all departments, and providing proposal implementation recommendations to the dean. All departments were required to submit proposals for consideration. The task group approved 27 service reduction proposals and 28 efficiency gains proposals, totaling approximately $2.7M in savings across two years. During this process, the task group faced a number of challenges, including a tight timeline for development and implementation (January to April 2011), a culture that historically supported decentralized planning, at times competing interests (e.g., research versus teaching objectives), and reductions in overall health care and postsecondary education government funding. Overall, faculty and staff preferred the PBMA approach to previous practices. Other institutions should use this example to set priorities in times of fiscal constraints.

  8. On Noisy Extensions of Nonholonomic Constraints

    NASA Astrophysics Data System (ADS)

    Gay-Balmaz, François; Putkaradze, Vakhtang

    2016-12-01

    We propose several stochastic extensions of nonholonomic constraints for mechanical systems and study the effects on the dynamics and on the conservation laws. Our approach relies on a stochastic extension of the Lagrange-d'Alembert framework. The mechanical system we focus on is the example of a Routh sphere, i.e., a rolling unbalanced ball on the plane. We interpret the noise in the constraint as either a stochastic motion of the plane, random slip or roughness of the surface. Without the noise, this system possesses three integrals of motion: energy, Jellet and Routh. Depending on the nature of noise in the constraint, we show that either energy, or Jellet, or both integrals can be conserved, with probability 1. We also present some exact solutions for particular types of motion in terms of stochastic integrals. Next, for an arbitrary nonholonomic system, we consider two different ways of including stochasticity in the constraints. We show that when the noise preserves the linearity of the constraints, then energy is preserved. For other types of noise in the constraint, e.g., in the case of an affine noise, the energy is not conserved. We study in detail a class of Lagrangian mechanical systems on semidirect products of Lie groups, with "rolling ball type" constraints. We conclude with numerical simulations illustrating our theories, and some pedagogical examples of noise in constraints for other nonholonomic systems popular in the literature, such as the nonholonomic particle, the rolling disk and the Chaplygin sleigh.

  9. The Role of Motivation, Perceived Constraints, and Constraint Negotiation Strategies in Students' Internship Selection Experience

    ERIC Educational Resources Information Center

    Batty, Kimberly A.

    2011-01-01

    The purpose of this study was to document the factors (i.e., motivation and perceived constraints) and processes (i.e., constraint negotiation) that influence students' selection of and satisfaction with their internship choice. The study was conducted using a quantitative approach, which included a focus group, a pilot study, and a…

  10. The Role of Motivation, Perceived Constraints, and Constraint Negotiation Strategies in Students' Internship Selection Experience

    ERIC Educational Resources Information Center

    Batty, Kimberly A.

    2011-01-01

    The purpose of this study was to document the factors (i.e., motivation and perceived constraints) and processes (i.e., constraint negotiation) that influence students' selection of and satisfaction with their internship choice. The study was conducted using a quantitative approach, which included a focus group, a pilot study, and a…

  11. Provider perspectives on constraints in providing maternal, neonatal and child health services in the Lao People's democratic republic: a qualitative study.

    PubMed

    Sychareun, Vanphanom; Phommachanh, Sysavanh; Soysouvanh, Soudavanh; Lee, Chaeun; Kang, Minah; Oh, Juhwan; Durham, Jo

    2013-12-27

    To reduce its high maternal and neonatal mortality rate and meet Millennium Development Goals four and five, Lao PDR has adopted a national 'Strategy and Planning Framework of Implementation of Maternal, Neonatal and Child Health Services'. This paper reports on implementation constraints identified in three demonstration sites. The objectives of this paper are to analyse health worker perceptions of the implementation of the strategy and constraints faced during implementation. A qualitative design was used with interviews conducted at health facilities in three demonstration provinces. Data were collected through key interviews with provincial/district hospital providers (n = 27), health centre staff (n = 8) and village health volunteers (n = 10). Data was analysed informed by Hanson et al's health system constraint framework. In each of the demonstration sites, the Maternal, Neonatal and Child Health program was generally well-understood and the different activities were being implemented. Perceived implementation constraints related mainly to a mix of supply and demand factors. Supply-side constraints related to inadequate human resources, poor remuneration, weak technical guidance, minimal supervision and limited equipment. Demand-side constraints related mainly to cost, limited access to transport, cultural practices and language. Other constraints related to broader strategic management and cross-sectoral contextual constraints. Contextual constraints included low levels of limited education, women's position in society and poor transport and communications networks. These factors influenced the implementation process and if not addressed, may reduce the effectiveness of the policy and scale-up. The Lao PDR has a well-defined Maternal, Neonatal and Child Health program. Analysis of the constraints experienced by service providers in implementing the program however, is essential for scaling-up the initiative. To achieve effective implementation

  12. COSMOLOGICAL CONSTRAINTS FROM GRAVITATIONAL LENS TIME DELAYS

    SciTech Connect

    Coe, Dan; Moustakas, Leonidas A.

    2009-11-20

    Future large ensembles of time delay (TD) lenses have the potential to provide interesting cosmological constraints complementary to those of other methods. In a flat universe with constant w including a Planck prior, The Large Synoptic Survey Telescope TD measurements for approx4000 lenses should constrain the local Hubble constant h to approx0.007 (approx1%), OMEGA{sub de} to approx0.005, and w to approx0.026 (all 1sigma precisions). Similar constraints could be obtained by a dedicated gravitational lens observatory (OMEGA) which would obtain precise TD and mass model measurements for approx100 well-studied lenses. We compare these constraints (as well as those for a more general cosmology) to the 'optimistic Stage IV' constraints expected from weak lensing, supernovae, baryon acoustic oscillations, and cluster counts, as calculated by the Dark Energy Task Force. TDs yield a modest constraint on a time-varying w(z), with the best constraint on w(z) at the 'pivot redshift' of z approx 0.31. Our Fisher matrix calculation is provided to allow TD constraints to be easily compared to and combined with constraints from other experiments. We also show how cosmological constraining power varies as a function of numbers of lenses, lens model uncertainty, TD precision, redshift precision, and the ratio of four-image to two-image lenses.

  13. Constraints in Genetic Programming

    NASA Technical Reports Server (NTRS)

    Janikow, Cezary Z.

    1996-01-01

    Genetic programming refers to a class of genetic algorithms utilizing generic representation in the form of program trees. For a particular application, one needs to provide the set of functions, whose compositions determine the space of program structures being evolved, and the set of terminals, which determine the space of specific instances of those programs. The algorithm searches the space for the best program for a given problem, applying evolutionary mechanisms borrowed from nature. Genetic algorithms have shown great capabilities in approximately solving optimization problems which could not be approximated or solved with other methods. Genetic programming extends their capabilities to deal with a broader variety of problems. However, it also extends the size of the search space, which often becomes too large to be effectively searched even by evolutionary methods. Therefore, our objective is to utilize problem constraints, if such can be identified, to restrict this space. In this publication, we propose a generic constraint specification language, powerful enough for a broad class of problem constraints. This language has two elements -- one reduces only the number of program instances, the other reduces both the space of program structures as well as their instances. With this language, we define the minimal set of complete constraints, and a set of operators guaranteeing offspring validity from valid parents. We also show that these operators are not less efficient than the standard genetic programming operators if one preprocesses the constraints - the necessary mechanisms are identified.

  14. Respiratory constraints during activities in daily life and the impact on health status in patients with early-stage COPD: a cross-sectional study

    PubMed Central

    van Helvoort, Hanneke AC; Willems, Laura M; Dekhuijzen, PN Richard; van Hees, Hieronymus WH; Heijdra, Yvonne F

    2016-01-01

    In patients with chronic obstructive pulmonary disease (COPD), exercise capacity is reduced, resulting over time in physical inactivity and worsened health status. It is unknown whether ventilatory constraints occur during activities of daily life (ADL) in early stages of COPD. The aim of this study was to assess respiratory mechanics during ADL and to study its consequences on dyspnoea, physical activity and health status in early-stage COPD compared with healthy controls. In this cross-sectional study, 39 early-stage COPD patients (mean FEV1 88±s.d. 12% predicted) and 20 controls performed 3 ADL: climbing stairs, vacuum cleaning and displacing groceries in a cupboard. Respiratory mechanics were measured during ADL. Physical activity was measured with accelerometry. Health status was assessed by the Nijmegen Clinical Screening Instrument. Compared with controls, COPD patients had greater ventilatory inefficiency and higher ventilatory requirements during ADL (P<0.05). Dyspnoea scores were increased in COPD compared with controls (P<0.001). During ADL, >50% of the patients developed dynamic hyperinflation in contrast to 10–35% of the controls. Higher dyspnoea was scored by patients with dynamic hyperinflation. Physical activity was low but comparable between both groups. From the patients, 55–84% experienced mild-to-severe problems in health status compared with 5–25% of the controls. Significant ventilatory constraints already occur in early-stage COPD patients during common ADL and result in increased dyspnoea. Physical activity level is not yet reduced, but many patients already experience limitations in health status. These findings reinforce the importance of early diagnosis of COPD and assessment of more than just spirometry. PMID:27734959

  15. Impact responses of the cervical spine: A computational study of the effects of muscle activity, torso constraint, and pre-flexion.

    PubMed

    Nightingale, Roger W; Sganga, Jake; Cutcliffe, Hattie; Bass, Cameron R 'Dale'

    2016-02-29

    Cervical spine injuries continue to be a costly societal problem. Future advancements in injury prevention depend on improved physical and computational models, which are predicated on a better understanding of the neck response during dynamic loading. Previous studies have shown that the tolerance of the neck is dependent on its initial position and its buckling behavior. This study uses a computational model to examine three important factors hypothesized to influence the loads experienced by vertebrae in the neck under compressive impact: muscle activation, torso constraints, and pre-flexion angle of the cervical spine. Since cadaver testing is not practical for large scale parametric analyses, these factors were studied using a previously validated computational model. On average, simulations with active muscles had 32% larger compressive forces and 25% larger shear forces-well in excess of what was expected from the muscle forces alone. In the short period of time required for neck injury, constraints on torso motion increased the average neck compression by less than 250N. The pre-flexion hypothesis was tested by examining pre-flexion angles from neutral (0°) to 64°. Increases in pre-flexion resulted in the largest increases in peak loads and the expression of higher-order buckling modes. Peak force and buckling modality were both very sensitive to pre-flexion angle. These results validate the relevance of prior cadaver models for neck injury and help explain the wide variety of cervical spine fractures that can result from ostensibly similar compressive loadings. They also give insight into the mechanistic differences between burst fractures and lower cervical spine dislocations.

  16. Constraints on relaxion windows

    NASA Astrophysics Data System (ADS)

    Choi, Kiwoon; Im, Sang Hui

    2016-12-01

    We examine the low energy phenomenology of the relaxion solution to the weak scale hierarchy problem. Assuming that the Hubble friction is responsible for a dissipation of the relaxion energy, we identify the cosmological relaxion window which corresponds to the parameter region compatible with a given value of the acceptable number of inflationary e-foldings. We then discuss a variety of observational constraints on the relaxion window, including those from astrophysical and cosmological considerations. We find that majority of the parameter space with a relaxion mass m ϕ ≳ 100 eV or a relaxion decay constant f ≲107GeV is excluded by existing constraints. There is an interesting parameter region with m ϕ ˜ 0 .2 - 10 GeV and f ˜ few - 200 TeV, which is allowed by existing constraints, but can be probed soon by future beam dump experiments such as the SHiP experiment, or by improved EDM experiments.

  17. Superselection from canonical constraints

    NASA Astrophysics Data System (ADS)

    Hall, Michael J. W.

    2004-08-01

    The evolution of both quantum and classical ensembles may be described via the probability density P on configuration space, its canonical conjugate S, and an ensemble Hamiltonian \\skew3\\tilde{H}[P,S] . For quantum ensembles this evolution is, of course, equivalent to the Schrödinger equation for the wavefunction, which is linear. However, quite simple constraints on the canonical fields P and S correspond to nonlinear constraints on the wavefunction. Such constraints act to prevent certain superpositions of wavefunctions from being realized, leading to superselection-type rules. Examples leading to superselection for energy, spin direction and 'classicality' are given. The canonical formulation of the equations of motion, in terms of a probability density and its conjugate, provides a universal language for describing classical and quantum ensembles on both continuous and discrete configuration spaces, and is briefly reviewed in an appendix.

  18. Constraint counting for frictional jamming

    NASA Astrophysics Data System (ADS)

    Quint, D. A.; Henkes, S.; Schwarz, J. M.

    2012-02-01

    While the frictionless jamming transition has been intensely studied in recent years, more realistic frictional packings are less well understood. In frictionless sphere packings, the transition is predicted by a simple mean-field constraint counting argument, the isostaticity argument. For frictional packings, a modified constraint counting argument, which includes slipping contacts at the Coulomb threshold, has had limited success in accounting for the transition. We propose that the frictional jamming transition is not mean field and is triggered by the nucleation of unstable regions, which are themselves dynamical objects due to the Coulomb criterion. We create frictional packings using MD simulations and test for the presence and shape of rigid clusters with the pebble game to identify the partition of the packing into stable and unstable regions. To understand the dynamics of these unstable regions we follow perturbations at contacts crucial to the stability of the ``frictional house of cards.''

  19. Observational constraints on exponential gravity

    SciTech Connect

    Yang, Louis; Lee, Chung-Chi; Luo, Ling-Wei; Geng, Chao-Qiang

    2010-11-15

    We study the observational constraints on the exponential gravity model of f(R)=-{beta}R{sub s}(1-e{sup -R/R}{sub s}). We use the latest observational data including Supernova Cosmology Project Union2 compilation, Two-Degree Field Galaxy Redshift Survey, Sloan Digital Sky Survey Data Release 7, and Seven-Year Wilkinson Microwave Anisotropy Probe in our analysis. From these observations, we obtain a lower bound on the model parameter {beta} at 1.27 (95% C.L.) but no appreciable upper bound. The constraint on the present matter density parameter is 0.245<{Omega}{sub m}{sup 0}<0.311 (95% C.L.). We also find out the best-fit value of model parameters on several cases.

  20. Phase II dose escalation study of image-guided adaptive radiotherapy for prostate cancer: Use of dose-volume constraints to achieve rectal isotoxicity

    SciTech Connect

    Vargas, Carlos; Yan Di; Kestin, Larry L.; Krauss, Daniel; Lockman, David M.; Brabbins, Donald S.; Martinez, Alvaro A. . E-mail: amartinez@beaumont.edu

    2005-09-01

    Purpose: In our Phase II prostate cancer Adaptive Radiation Therapy (ART) study, the highest possible dose was selected on the basis of normal tissue tolerance constraints. We analyzed rectal toxicity rates in different dose levels and treatment groups to determine whether equivalent toxicity rates were achieved as hypothesized when the protocol was started. Methods and Materials: From 1999 to 2002, 331 patients with clinical stage T1 to T3, node-negative prostate cancer were prospectively treated with three-dimensional conformal adaptive RT. A patient-specific confidence-limited planning target volume was constructed on the basis of 5 CT scans and 4 sets of electronic portal images after the first 4 days of treatment. For each case, the rectum (rectal solid) was contoured in its entirety. The rectal wall was defined by use of a 3-mm wall thickness (median volume: 29.8 cc). The prescribed dose level was chosen using the following rectal wall dose constraints: (1) Less than 30% of the rectal wall volume can receive more than 75.6 Gy. (2) Less than 5% of the rectal wall can receive more than 82 Gy. Low-risk patients (PSA < 10, Stage {<=} T2a, Gleason score < 7) were treated to the prostate alone (Group 1). All other patients, intermediate and high risk, where treated to the prostate and seminal vesicles (Group 2). The risk of chronic toxicity (NCI Common Toxicity Criteria 2.0) was assessed for the different dose levels prescribed. HIC approval was acquired for all patients. Median follow-up was 1.6 years. Results: Grade 2 chronic rectal toxicity was experienced by 34 patients (10%) (9% experienced rectal bleeding, 6% experienced proctitis, 3% experienced diarrhea, and 1% experienced rectal pain) at a median interval of 1.1 year. Nine patients (3%) experienced grade 3 or higher chronic rectal toxicity (1 Grade 4) at a median interval of 1.2 years. The 2-year rates of Grade 2 or higher and Grade 3 or higher chronic rectal toxicity were 17% and 3%, respectively. No

  1. Disentangling Robust Developmental Constraints from the Instructionally Mutable: Young Children's Epistemic Reasoning about a Study of Their Own Design

    ERIC Educational Resources Information Center

    Metz, Kathleen E.

    2011-01-01

    This study examines first graders' epistemic reasoning, in tacit "practical epistemologies" reflected in thinking about an investigation of their own design. I analyzed children's epistemic reasoning, following a design experiment scaffolding increasing regulation of scientific inquiry in a domain they studied in depth. Participants…

  2. Disentangling Robust Developmental Constraints from the Instructionally Mutable: Young Children's Epistemic Reasoning about a Study of Their Own Design

    ERIC Educational Resources Information Center

    Metz, Kathleen E.

    2011-01-01

    This study examines first graders' epistemic reasoning, in tacit "practical epistemologies" reflected in thinking about an investigation of their own design. I analyzed children's epistemic reasoning, following a design experiment scaffolding increasing regulation of scientific inquiry in a domain they studied in depth. Participants…

  3. Constraint programming based biomarker optimization.

    PubMed

    Zhou, Manli; Luo, Youxi; Sun, Guoquan; Mai, Guoqin; Zhou, Fengfeng

    2015-01-01

    Efficient and intuitive characterization of biological big data is becoming a major challenge for modern bio-OMIC based scientists. Interactive visualization and exploration of big data is proven to be one of the successful solutions. Most of the existing feature selection algorithms do not allow the interactive inputs from users in the optimizing process of feature selection. This study investigates this question as fixing a few user-input features in the finally selected feature subset and formulates these user-input features as constraints for a programming model. The proposed algorithm, fsCoP (feature selection based on constrained programming), performs well similar to or much better than the existing feature selection algorithms, even with the constraints from both literature and the existing algorithms. An fsCoP biomarker may be intriguing for further wet lab validation, since it satisfies both the classification optimization function and the biomedical knowledge. fsCoP may also be used for the interactive exploration of bio-OMIC big data by interactively adding user-defined constraints for modeling.

  4. A Petrologic Study of the IAB Iron Meteorites: Constraints on the Formation of the IAB-Winonaite Parent Body

    NASA Technical Reports Server (NTRS)

    Benedix, G. K.; McCoy, T. J.; Keil, K.; Love, S. G.

    1998-01-01

    We have studied IAB iron meteorites and their silicate-bearing inclusions to elucidate the origin of their parent body. We have divided IAB irons into five categories which best describe the inclusions and other properties of the irons.

  5. A Petrologic Study of the IAB Iron Meteorites: Constraints on the Formation of the IAB-Winonaite Parent Body

    NASA Technical Reports Server (NTRS)

    Benedix, G. K.; McCoy, T. J.; Keil, K.; Love, S. G.

    1998-01-01

    We have studied IAB iron meteorites and their silicate-bearing inclusions to elucidate the origin of their parent body. We have divided IAB irons into five categories which best describe the inclusions and other properties of the irons.

  6. Provider perspectives on constraints in providing maternal, neonatal and child health services in the Lao People’s democratic republic: a qualitative study

    PubMed Central

    2013-01-01

    Background To reduce its high maternal and neonatal mortality rate and meet Millennium Development Goals four and five, Lao PDR has adopted a national ‘Strategy and Planning Framework of Implementation of Maternal, Neonatal and Child Health Services’. This paper reports on implementation constraints identified in three demonstration sites. Methods The objectives of this paper are to analyse health worker perceptions of the implementation of the strategy and constraints faced during implementation. A qualitative design was used with interviews conducted at health facilities in three demonstration provinces. Data were collected through key interviews with provincial/district hospital providers (n = 27), health centre staff (n = 8) and village health volunteers (n = 10). Data was analysed informed by Hanson et al’s health system constraint framework. Results In each of the demonstration sites, the Maternal, Neonatal and Child Health program was generally well-understood and the different activities were being implemented. Perceived implementation constraints related mainly to a mix of supply and demand factors. Supply-side constraints related to inadequate human resources, poor remuneration, weak technical guidance, minimal supervision and limited equipment. Demand-side constraints related mainly to cost, limited access to transport, cultural practices and language. Other constraints related to broader strategic management and cross-sectoral contextual constraints. Contextual constraints included low levels of limited education, women’s position in society and poor transport and communications networks. These factors influenced the implementation process and if not addressed, may reduce the effectiveness of the policy and scale-up. Conclusion The Lao PDR has a well-defined Maternal, Neonatal and Child Health program. Analysis of the constraints experienced by service providers in implementing the program however, is essential for scaling-up the

  7. The Considerations of the Superintendent in the Development of the School Budget during Times of Fiscal Constraint: A Case Study

    ERIC Educational Resources Information Center

    Witt, Jeffrey

    2012-01-01

    John Smith is the superintendent of Green Hill Public Schools. This case study follows John through the whole budget process from July 2011 to July 2012. An interpretative perspective was used to tell his story. Ten interviews were given from October 2011 to July 2012. Newspaper articles and the minutes from meetings were analyzed and used as…

  8. Intentional Control and Operational Constraints in Prosodic Phrasing: A Study of Picture-Elicited Narrations by French Children

    ERIC Educational Resources Information Center

    Vion, Monique; Colas, Annie

    2009-01-01

    This study deals with the determinants of prosodic phrasing in French schoolchildren's narratives. Children (aged 7 to 11) told picture stories to a silent same-age peer. The establishment of temporal and/or causal relations between the events was more or less guided by the drawings (ordered vs. arbitrary sequences). The comprehension of the…

  9. The Considerations of the Superintendent in the Development of the School Budget during Times of Fiscal Constraint: A Case Study

    ERIC Educational Resources Information Center

    Witt, Jeffrey

    2012-01-01

    John Smith is the superintendent of Green Hill Public Schools. This case study follows John through the whole budget process from July 2011 to July 2012. An interpretative perspective was used to tell his story. Ten interviews were given from October 2011 to July 2012. Newspaper articles and the minutes from meetings were analyzed and used as…

  10. A constraint algorithm for singular Lagrangians subjected to nonholonomic constraints

    SciTech Connect

    de Leon, M.; de Diego, D.M.

    1997-06-01

    We construct a constraint algorithm for singular Lagrangian systems subjected to nonholonomic constraints which generalizes that of Dirac for constrained Hamiltonian systems. {copyright} {ital 1997 American Institute of Physics.}

  11. [Constraints on the knee caused by meniscal and ligament derangement. Study of the internal condylotibial joint. Experimental cinematic method].

    PubMed

    Frain, P; Fontaine, C; D'Hondt, D

    1984-01-01

    In a previous paper the authors have demonstrated that the polycentric curve of the surface of the medial condyle of the femur is a logarithmic spiral arch whose centre is the point of attachment of the medial ligament. In the present study, the totality of the menisco-ligamentous system was considered and studied on cadavers following a geometric model. It is shown that the ligament system controls combined or successive movements of gliding or rotation of the condyle on the tibial plateau in such a way as to avoid any cam effect or additional strain. Division of ligaments or excision of a meniscus leads to an increase in strain which varies in relation to the type of lesion. The increase is moderate after division of the anterior cruciate ligament, greater after division of the posterior cruciate ligament and severe after meniscectomy especially when associated with ligamentous division.

  12. A heavy mineral study of sandstones from the eastern Murzuq Basin, Libya: Constraints on provenance and stratigraphic correlation

    NASA Astrophysics Data System (ADS)

    Morton, Andrew C.; Meinhold, Guido; Howard, James P.; Phillips, Richard J.; Strogen, Dominic; Abutarruma, Yousef; Elgadry, Mohamed; Thusu, Bindra; Whitham, Andrew G.

    2011-11-01

    This paper presents the results of an integrated heavy mineral and mineral chemical study of Precambrian-Mesozoic clastic sediments from the eastern Murzuq Basin. The purpose of this study was to constrain the provenance of sediment and to assess the value of heavy minerals as a stratigraphic tool. Conventional heavy mineral analysis was carried out on 64 samples, tourmaline geochemical analysis on 25 samples, garnet geochemical analysis on four samples, rutile geochemical analysis on 21 samples, and clinopyroxene geochemical analysis on two samples. The study indicates that heavy mineral analysis is a valuable tool for understanding the provenance of Palaeozoic and Mesozoic clastic sediments in Libya, despite the intense weathering that surface samples have undergone. Based on heavy mineral ratios and mineral chemical data, there appear to be three key events when the provenance signature changed within the Palaeozoic-Mesozoic sedimentary succession at the eastern Murzuq Basin: (i) at the base of the Tanezzuft Formation (early Silurian), (ii) at the base of the Tadrart Formation (Early Devonian), and (iii) at the base of the Mrar Formation (Carboniferous), subdividing the succession into four intervals (Hasawnah-Mamuniyat, Tanezzuft-Akakus, Tadrart-Awaynat Wanin, and Mrar-Nubian). There is probably also an event between the Precambrian and the Hasawnah Formation (Cambrian), but there are currently insufficient data to prove this unequivocally. Comparing data of the present study with results from the previous work in the Kufra Basin it is evident that heavy mineral data provide useful evidence for differences in provenance both regionally and stratigraphically in basins of the central Sahara.

  13. Constraints in meeting food safety and quality requirements in the Turkish dairy industry: a case study of Izmir province.

    PubMed

    Demirbaş, Nevin; Karagözlü, Cem

    2008-02-01

    Recent global developments concerning food quality and food safety have influenced and stimulated food legislation in Turkey in accordance with internal and international trade and agreements. In this study, the way in which the dairy industry conforms to this legislation was analyzed through a case study of Izmir province, which generally has all the structural characteristics of the dairy sector in Turkey. A survey in which dairy plant managers responded to a special questionnaire was used to collect data from 86 dairy plants chosen on the basis of proportional sampling. According to the results of this study, (i) there are many dairy processors in the region, (ii) most managers have a limited education concerning their positions, (iii) most firms handle small volumes of milk and have little control over the raw milk supply, (iv) resources are too limited in these firms, limiting their ability to adopt most regulations, and (v) few processors apply the regulatory practices imposed by governmental agencies. Thus, food legislation is not enough to ensure food safety in the dairy industry in Turkey. Technical and educational support should be given to farmers and the staff of dairy firms by the Ministry of Agriculture to form an appropriate food safety infrastructure in Turkey for the milk and processed dairy products industry.

  14. A cross-sectional study of pedagogical strategies in nursing education: opportunities and constraints toward using effective pedagogy.

    PubMed

    Pagnucci, Nicola; Carnevale, Franco A; Bagnasco, Annamaria; Tolotti, Angela; Cadorin, Lucia; Sasso, Loredana

    2015-08-25

    The continuous, rapid evolution of medical technology, the public need for ever more complex health-care services and the stagnant global economic situation have posed difficult new challenges for the nursing profession. The need to integrate knowledge, technical skill and ethical conduct in nursing practice has become ever more evident, particularly in response to the emerging challenges over recent years. Major research studies have highlighted that high-quality responses to health needs is highly dependent on both the education received by health care professionals and the pedagogical strategies employed in such training. The aim of this study was to identify the pedagogical strategies used by teachers in nursing programs in the Italian university system and to classify them according to the didactic architectures that are used. The study sample was recruited from the entire population of nursing instructors teaching in all years of their respective programs, in every Italian university with a nursing program. A three-part questionnaire, based on a Calvani taxonomy, was designed to collect both demographic and cultural information on the sample subjects, as well as the pedagogical strategies that they may have used in their teaching practices, was administered to all nursing instructors. A five-point Likert scale was used to measure the frequency of use of different pedagogical strategies. On the whole, 992 teachers participated in the study (80.1% of the teachers contacted). Experience data suggest a highly-educated overall instructor population. The settings in which the participants carried out their teaching activities were represented mostly by large lecture halls and the number of students in their classes were for the most part rather large; over 60. Frequency of use revealed that the most commonly used method was the traditional lecture. Indeed, 85.7% of the respondents "often" or "always" used pedagogical strategies belonging to a 'receptive

  15. Repair Process Improvement at the Ogden Air Logistics Center, Landing Gear Division: A Case Study in the Application of the Theory of Constraints

    DTIC Science & Technology

    1993-09-01

    Eliyahu M. Goldratt . It emphasizes constraint identification and exploitation as the key to focusing limited time and resources on processes to achieve... Eliyahu M. Theory of Constraints. Croton-on-Hudson NY: North River Press, Inc., 1990. 113 Goldratt , Eliyahu M. and Jeff Cox. The GaI. Croton-on-Hudson NY...addition, many of the existing validation efforts have been conducted by the Goldratt Institute and may not constitute truly independent looks at what

  16. A Framework for Dynamic Constraint Reasoning Using Procedural Constraints

    NASA Technical Reports Server (NTRS)

    Jonsson, Ari K.; Frank, Jeremy D.

    1999-01-01

    Many complex real-world decision and control problems contain an underlying constraint reasoning problem. This is particularly evident in a recently developed approach to planning, where almost all planning decisions are represented by constrained variables. This translates a significant part of the planning problem into a constraint network whose consistency determines the validity of the plan candidate. Since higher-level choices about control actions can add or remove variables and constraints, the underlying constraint network is invariably highly dynamic. Arbitrary domain-dependent constraints may be added to the constraint network and the constraint reasoning mechanism must be able to handle such constraints effectively. Additionally, real problems often require handling constraints over continuous variables. These requirements present a number of significant challenges for a constraint reasoning mechanism. In this paper, we introduce a general framework for handling dynamic constraint networks with real-valued variables, by using procedures to represent and effectively reason about general constraints. The framework is based on a sound theoretical foundation, and can be proven to be sound and complete under well-defined conditions. Furthermore, the framework provides hybrid reasoning capabilities, as alternative solution methods like mathematical programming can be incorporated into the framework, in the form of procedures.

  17. Thermodynamic optimization under topological constraints

    NASA Astrophysics Data System (ADS)

    Balakumar, Thevika

    Computational thermodynamics is a powerful tool for solving practically important problems including the design of new materials and the analysis of their internal and external stability. This thesis contributes to computational thermodynamics by proposing several practical solutions to eliminate the so-called thermodynamic artifacts rather frequently found in thermodynamic assessments. First, a method is developed to eliminate the artifacts such as inverted miscibility gaps in the liquid phase at high-temperatures and reappearance of the liquid phase at low-temperatures or reappearance of a solid phase at elevated temperatures. This method is based on introducing a sufficiently dense mesh of knots (not related to experimental points utilized in the optimization) and ensuring that specific inequality conditions (topological constraints) governing the appearance of the phase diagram are satisfied in these knots. A feasibility of the approach proposed is exemplified by carrying out a re-optimization of the Mg-Sb system. Generally re-optimization of a system would take months to get the optimized results. Hence, to minimize time needed to get rid of artifacts, two different quick correction methods are developed to eliminate the unrealistic inverted miscibility gap in the liquid phase at elevated temperatures. Both methods employ optimization under topological constraints via controlling the sign of the second derivative of the Gibbs energy. Their applicability is exemplified on the Sn-Zr system. Also, a theoretical study was done on undulate phase boundaries. Usually, an inflection point on a phase boundary is considered as an unambiguous indication that one of the phases participating in the equilibrium is internally unstable, i.e., that it is prone to phase separation. It has been generally assumed that an inflection point may occur only if the thermodynamic model of this phase contains an excess Gibbs energy term. It is shown that in contrast to this assumption

  18. Feature matching method with multigeometric constraints

    NASA Astrophysics Data System (ADS)

    Xu, Dong; Huang, Qian; Liu, Wenyong; Bessaih, Hadjar; Li, Chidong

    2016-11-01

    Feature correspondence is one of the essential difficulties in image processing, given that it is applied within a wide range in computer vision. Even though it has been studied for many years, feature correspondence is still far from being ideal. This paper proposes a multigeometric-constraint algorithm for finding correspondences between two sets of features. It does so by considering interior angles and edge lengths of triangles formed by third-order tuples of points. Multigeometric-constraints are formulated using matrices representing triangle similarities. The experimental evaluation showed that the multigeometric-constraint algorithm can significantly improve the matching precision and is robust to most geometric and photometric transformations including rotation, scale change, blur, viewpoint change, and JPEG compression as well as illumination change. The multigeometric-constraint algorithm was applied to object recognition which includes extraprocessing and affine transformation. The results showed that this approach works well for this recognition.

  19. A geochemical study of the winonaites: Evidence for limited partial melting and constraints on the precursor composition

    NASA Astrophysics Data System (ADS)

    Hunt, Alison C.; Benedix, Gretchen K.; Hammond, Samantha J.; Bland, Philip A.; Rehkämper, Mark; Kreissig, Katharina; Strekopytov, Stanislav

    2017-02-01

    The winonaites are primitive achondrites which are associated with the IAB iron meteorites. Textural evidence implies heating to at least the Fe, Ni-FeS cotectic, but previous geochemical studies are ambiguous about the extent of silicate melting in these samples. Oxygen isotope evidence indicates that the precursor material may be related to the carbonaceous chondrites. Here we analysed a suite of winonaites for modal mineralogy and bulk major- and trace-element chemistry in order to assess the extent of thermal processing as well as constrain the precursor composition of the winonaite-IAB parent asteroid. Modal mineralogy and geochemical data are presented for eight winonaites. Textural analysis reveals that, for our sub-set of samples, all except the most primitive winonaite (Northwest Africa 1463) reached the Fe, Ni-FeS cotectic. However, only one (Tierra Blanca) shows geochemical evidence for silicate melting processes. Tierra Blanca is interpreted as a residue of small-degree silicate melting. Our sample of Winona shows geochemical evidence for extensive terrestrial weathering. All other winonaites studied here (Fortuna, Queen Alexander Range 94535, Hammadah al Hamra 193, Pontlyfni and NWA 1463) have chondritic major-element ratios and flat CI-normalised bulk rare-earth element patterns, suggesting that most of the winonaites did not reach the silicate melting temperature. The majority of winonaites were therefore heated to a narrow temperature range of between ∼1220 (the Fe, Ni-FeS cotectic temperature) and ∼1370 K (the basaltic partial melting temperature). Silicate inclusions in the IAB irons demonstrate partial melting did occur in some parts of the parent body (Ruzicka and Hutson, 2010), thereby implying heterogeneous heat distribution within this asteroid. Together, this indicates that melting was the result of internal heating by short-lived radionuclides. The brecciated nature of the winonaites suggests that the parent body was later disrupted by

  20. (non) Emergent Constraints

    NASA Astrophysics Data System (ADS)

    Jackson, C. S.; Hattab, M. W.; Huerta, G.

    2014-12-01

    Emergent constraints are observable quantities that provide some physical basis for testing or predicting how a climate model will respond to greenhouse gas forcing. Very few such constraints have been identified for the multi-model CMIP archive. Here we explore the question of whether constraints that apply to a single model, a perturbed parameter ensemble (PPE) of the Community Atmosphere Model (CAM3.1), can be applied to predicting the climate sensitivities of models within the CMIP archive. In particular we construct our predictive patterns from multivariate EOFs of the CAM3.1 ensemble control climate. Multiple regressive statistical models were created that do an excellent job of predicting CAM3.1 sensitivity to greenhouse gas forcing. However, these same patterns fail spectacularly to predict sensitivities of models within the CMIP archive. We attribute this failure to several factors. First, and perhaps the most important, is that the structures affecting climate sensitivity in CAM3.1 have a unique signature in the space of our multivariate EOF patterns that are unlike any other climate model. That is to say, we should not expect CAM3.1 to represent the way another models within CMIP archive respond to greenhouse gas forcing. The second, perhaps related, reason is that the CAM3.1 PPE does a poor job of spanning the range of climates and responses found within the CMIP archive. We shall discuss the implications of these results for the prospect of finding emergent constraints within the CMIP archive. We will also discuss what this may mean for establishing uncertainties in climate projections.

  1. Neodymium and strontium isotopic study of Australasian tektites - New constraints on the provenance and age of target materials

    NASA Technical Reports Server (NTRS)

    Blum, Joel D.; Papanastassiou, D. A.; Wasserburg, G. J.; Koeberl, C.

    1992-01-01

    The Nd and Sr isotopic compositions of Australasian tectites (including two flanged Australian tectites, two low-SiO2 Muong Nong-type tectites, and three high-SiO2 Muong Nong-type tectites) and the Nd, Sm, Sr, and Rb concentrations were investigated by isotope-dilution thermal ionization mass spectrometry, and the Sm-Nd and Rb-Sr isotope systematics were used to study the characteristics of the parental material. It is shown that the Nd and Sr isotopic data provide evidence that all Australasian tektites were derived from a single sedimentary formation with a narrow range of stratigraphic ages close to 170 Ma. It is suggested that all of the Australasian tektites were derived from a single impact event and that the australites represent the upper part of a melt sheet ejected at high velocity, whereas the indochinites represent melts formed at a lower level in the target material distributed closer to the area of the impact.

  2. An asteroseismic study of the β Cephei star θ Ophiuchi: constraints on global stellar parameters and core overshooting

    NASA Astrophysics Data System (ADS)

    Briquet, M.; Morel, T.; Thoul, A.; Scuflaire, R.; Miglio, A.; Montalbán, J.; Dupret, M.-A.; Aerts, C.

    2007-11-01

    We present a seismic study of the β Cephei star θ Ophiuchi. Our analysis is based on the observation of one radial mode, one rotationally split l = 1 triplet and three components of a rotationally split l = 2 quintuplet for which the m values were well identified by spectroscopy. We identify the radial mode as fundamental, the triplet as p1 and the quintuplet as g1. Our non-local thermodynamic equilibrium abundance analysis results in a metallicity and CNO abundances in full agreement with the most recent updated solar values. With X ∈ [0.71, 0.7211] and Z ∈ [0.009, 0.015], and using the Asplund et al. mixture but with a Ne abundance about 0.3 dex larger, the matching of the three independent modes enables us to deduce constrained ranges for the mass (M = 8.2 +/- 0.3Msolar) and central hydrogen abundance (Xc = 0.38 +/- 0.02) of θ Oph and to prove the occurrence of core overshooting (αov = 0.44 +/- 0.07). We also derive an equatorial rotation velocity of 29 +/- 7 km s-1. Moreover, we show that the observed non-equidistance of the l = 1 triplet can be reproduced by the second-order effects of rotation. Finally, we show that the observed rotational splitting of two modes cannot rule out a rigid rotation model.

  3. Generation and differentiation of group II kimberlites: constraints from a high-pressure experimental study to 10 GPa

    NASA Astrophysics Data System (ADS)

    Ulmer, Peter; Sweeney, Russell J.

    2002-06-01

    Experiments have been performed in the multicomponent (natural) bulk system to constrain the conditions of generation and differentiation of a K-rich group II kimberlite (now also referred to as orangeite). The group II composition examined was saturated in olivine, orthopyroxene, and garnet at near liquidus conditions in the pressure range 4 to 10 GPa. In the range 2 to 3 GPa, the liquidus phase was olivine only. The potassic nature of the melts in the bulk compositions studied was ensured by the absence of any K-bearing phase in the residual assemblage at P > 4 GPa. Phlogopite is destabilized toward higher pressures by a carbonation reaction of the type phlogopite + CO 2 = enstatite + garnet + K 2CO 3 (liquid) + H 2O leading to alkalic, carbonatitic liquids coexisting with a garnet-peridotite (harzburgite or lherzolite) residue over a wide pressure-temperature space at pressures in excess of 4 GPa. Evidently, CO 2-bearing systems do not favor the stability of phlogopite and/or K-richterite amphibole at pressures in excess of 4 to 5 GPa, and it is suggested that the carbonate-bearing and potassic character of any mantle melt originating from this depth is most likely the product of a two-stage process: either a carbonate-bearing protolith is invaded by a potassic melt or fluid (probably supercritical), or a potassic protolith (after metasomatism) has been invaded by a carbonatite melt.

  4. Constraint-based scheduling

    NASA Technical Reports Server (NTRS)

    Zweben, Monte

    1991-01-01

    The GERRY scheduling system developed by NASA Ames with assistance from the Lockheed Space Operations Company, and the Lockheed Artificial Intelligence Center, uses a method called constraint based iterative repair. Using this technique, one encodes both hard rules and preference criteria into data structures called constraints. GERRY repeatedly attempts to improve schedules by seeking repairs for violated constraints. The system provides a general scheduling framework which is being tested on two NASA applications. The larger of the two is the Space Shuttle Ground Processing problem which entails the scheduling of all inspection, repair, and maintenance tasks required to prepare the orbiter for flight. The other application involves power allocations for the NASA Ames wind tunnels. Here the system will be used to schedule wind tunnel tests with the goal of minimizing power costs. In this paper, we describe the GERRY system and its applications to the Space Shuttle problem. We also speculate as to how the system would be used for manufacturing, transportation, and military problems.

  5. Constraint-based scheduling

    NASA Technical Reports Server (NTRS)

    Zweben, Monte

    1991-01-01

    The GERRY scheduling system developed by NASA Ames with assistance from the Lockheed Space Operations Company, and the Lockheed Artificial Intelligence Center, uses a method called constraint-based iterative repair. Using this technique, one encodes both hard rules and preference criteria into data structures called constraints. GERRY repeatedly attempts to improve schedules by seeking repairs for violated constraints. The system provides a general scheduling framework which is being tested on two NASA applications. The larger of the two is the Space Shuttle Ground Processing problem which entails the scheduling of all the inspection, repair, and maintenance tasks required to prepare the orbiter for flight. The other application involves power allocation for the NASA Ames wind tunnels. Here the system will be used to schedule wind tunnel tests with the goal of minimizing power costs. In this paper, we describe the GERRY system and its application to the Space Shuttle problem. We also speculate as to how the system would be used for manufacturing, transportation, and military problems.

  6. Constraint-based scheduling

    NASA Technical Reports Server (NTRS)

    Zweben, Monte

    1993-01-01

    The GERRY scheduling system developed by NASA Ames with assistance from the Lockheed Space Operations Company, and the Lockheed Artificial Intelligence Center, uses a method called constraint-based iterative repair. Using this technique, one encodes both hard rules and preference criteria into data structures called constraints. GERRY repeatedly attempts to improve schedules by seeking repairs for violated constraints. The system provides a general scheduling framework which is being tested on two NASA applications. The larger of the two is the Space Shuttle Ground Processing problem which entails the scheduling of all the inspection, repair, and maintenance tasks required to prepare the orbiter for flight. The other application involves power allocation for the NASA Ames wind tunnels. Here the system will be used to schedule wind tunnel tests with the goal of minimizing power costs. In this paper, we describe the GERRY system and its application to the Space Shuttle problem. We also speculate as to how the system would be used for manufacturing, transportation, and military problems.

  7. Constraints on core formation from systematic study of metal-silicate partitioning on a great number of siderophile elements

    SciTech Connect

    Siebert, J; Ryerson, F J

    2008-10-27

    The abundances of siderophile elements in the Earth's mantle are the result of core formation in the early Earth. Many variables are involved in the prediction of metal/silicate siderophile partition coefficients during core segregation: pressure, temperature, oxygen fugacity, silicate and metal compositions. Despite publications of numerous results of metal-silicate experiments, the experimental database and predictive expressions for elements partitioning are hampered by a lack of systematic study to separate and evaluate the effects of each variable. Only a relatively complete experimental database that describes Ni and Co partitioning now exists but is not sufficient to unambiguously decide between the most popular model for core formation with a single stage core-mantle equilibration at the bottom of a deep magma ocean (e.g. Li and Agee, 2001) and more recent alternative models (e.g. Wade and Wood, 2005; Rubie et al., 2007). In this experimental work, systematic study of metal silicate partitioning is presented for elements normally regarded as moderately siderophile (Mo, As, Ge, W, P, Ni, Co), slightly siderophile (Zn, Ga, Mn, V, Cr) and refractory lithophile (Nb, Ta). Using a new piston-cylinder design assembly allows us to present a suite of isobaric partitioning experiments at 3 GPa within a temperature range from 1600 to 2600 C and over a range of relative oxygen fugacity from IW-1.5 to IW-3.5. Silicate melts range from basaltic to peridotite in composition. The individual effect of pressure is also investigated through a combination of piston cylinder and multi anvil isothermal experiments from 0.5 to 18 GPa at 1900 C. Absolute measurements of partitioning coefficients combining EMP and LA-ICPMS analytical methods are provided. New results are obtained for elements whose partitioning behavior is usually poorly constrained and not integrated into any accretion or core formation models. We find notably that Ge, As, Mo become less siderophile with

  8. Constraints on core formation from systematic study of metal-silicate partitioning on a great number of siderophile elements

    NASA Astrophysics Data System (ADS)

    Siebert, J.; Ryerson, F. J.

    2008-12-01

    The abundances of siderophile elements in the Earth's mantle are the result of core formation in the early Earth. Many variables are involved in the prediction of metal/silicate siderophile partition coefficients during core segregation: pressure, temperature, oxygen fugacity, silicate and metal compositions. Despite publications of numerous results of metal-silicate experiments, the experimental database and predictive expressions for elements partitioning are hampered by a lack of systematic study to separate and evaluate the effects of each variable. Only a relatively complete experimental database that describes Ni and Co partitioning now exists but is not sufficient to unambiguously decide between the most popular model for core formation with a single stage core-mantle equilibration at the bottom of a deep magma ocean (e.g. Li and Agee, 2001) and more recent alternative models (e.g. Wade and Wood, 2005; Rubie et al., 2007). In this experimental work, systematic study of metal silicate partitioning is presented for elements normally regarded as moderately siderophile (Mo, As, Ge, W, P, Ni, Co), slightly siderophile (Zn, Ga, Mn, V, Cr) and refractory lithophile (Nb, Ta). Using a new piston-cylinder design assembly allows us to present a suite of isobaric partitioning experiments at 3 GPa within a temperature range from 1600 to 2600° C and over a range of relative oxygen fugacity from IW-1.5 to IW-3.5. Silicate melts range from basaltic to peridotite in composition. The individual effect of pressure is also investigated through a combination of piston cylinder and multi anvil isothermal experiments from 0.5 to 18 GPa at 1900° C. Absolute measurements of partitioning coefficients combining EMP and LA-ICPMS analytical methods are provided. New results are obtained for elements whose partitioning behavior is usually poorly constrained and not integrated into any accretion or core formation models. We find notably that Ge, As, Mo become less siderophile with

  9. Local constraints to access appropriate malaria treatment in the context of parasite resistance in Cambodia: a qualitative study.

    PubMed

    Verschuere, Jesse; Decroo, Tom; Lim, Dara; Kindermans, Jean-Marie; Nguon, Chea; Huy, Rekol; Alkourdi, Yasmine; Peeters Grietens, Koen; Gryseels, Charlotte

    2017-02-17

    Despite emerging drug resistance in Cambodia, artemisinin-based combination therapy (ACT) is still the most efficacious therapy. ACT is available free of charge in the Cambodian public sector and at a subsidized rate in the private sector. However, un- and mistreated cases in combination with population movements may lead to the further spread of resistant parasites, stressing the importance of understanding how the perceived aetiology of malaria and associated health-seeking behaviour may delay access to appropriate treatment. A qualitative study explored these factors after an epidemiological survey confirmed parasite resistance in Preah Vihear province. In Cambodian cosmology, illnesses can be inflicted by supernatural beings or originate from 'natural' causes because of disorder in the social, domestic or outdoor environment. Initial treatment options consist of cheap and accessible home-based care (manual therapy, herbs and biomedical medication) targeting single symptoms. If there is no steady recovery or if the condition quickly aggravates, care will be sought from 'village doctors', public health facilities, private pharmacies or, in case of suspicion of a supernatural cause, from a specialized indigenous healer. The choice of provider is mostly based on the family's financial situation, access to and trust in the provider, and the congruence between the suspected aetiology of the illness and the treatment offered by the provider. Different treatment options are often combined during the same illness episode through a serial process of trial and error guided by the observable improvements in the patient's condition. Cambodian perceptions of illness that focus on single symptoms and their perceived severity may lead to the identification of one or multiple illnesses at the same time, rarely suspecting malaria from the start and implying different patterns of health seeking behaviour and treatment choice. However, decisions to self-diagnose and treat at home

  10. Advancing Solar Irradiance Measurement for Climate-Related Studies: Accurate Constraint on Direct Aerosol Radiative Effect (DARE)

    NASA Technical Reports Server (NTRS)

    Tsay, Si-Chee; Ji, Q. Jack

    2011-01-01

    Earth's climate is driven primarily by solar radiation. As summarized in various IPCC reports, the global average of radiative forcing for different agents and mechanisms, such as aerosols or CO2 doubling, is in the range of a few W/sq m. However, when solar irradiance is measured by broadband radiometers, such as the fleet of Eppley Precision Solar Pyranometers (PSP) and equivalent instrumentation employed worldwide, the measurement uncertainty is larger than 2% (e.g., WMO specification of pyranometer, 2008). Thus, out of the approx. 184 W/sq m (approx.263 W/sq m if cloud-free) surface solar insolation (Trenberth et al. 2009), the measurement uncertainty is greater than +/-3.6 W/sq m, overwhelming the climate change signals. To discern these signals, less than a 1 % measurement uncertainty is required and is currently achievable only by means of a newly developed methodology employing a modified PSP-like pyranometer and an updated calibration equation to account for its thermal effects (li and Tsay, 2010). In this talk, we will show that some auxiliary measurements, such as those from a collocated pyrgeometer or air temperature sensors, can help correct historical datasets. Additionally, we will also demonstrate that a pyrheliometer is not free of the thermal effect; therefore, comparing to a high cost yet still not thermal-effect-free "direct + diffuse" approach in measuring surface solar irradiance, our new method is more economical, and more likely to be suitable for correcting a wide variety of historical datasets. Modeling simulations will be presented that a corrected solar irradiance measurement has a significant impact on aerosol forcing, and thus plays an important role in climate studies.

  11. Extensional Tectonics and Paleoclimate of the Albertine and Edward Rifts: Constraints from Integrated Seismic Reflection and Topographic Studies

    NASA Astrophysics Data System (ADS)

    Karp, T.; McGlue, M. M.; Scholz, C. A.; Kasande, R.; Mugisha, F.

    2004-12-01

    Lakes Albert and Edward are among the largest lakes in Africa and form substantial reservoirs for tropical precipitation within the Upper Nile Watershed (UNW), the equatorial headwaters supporting annual discharge of the main Nile River into the Mediterranean Sea. Extensional processes forming Lakes Albert and Edward have driven landscape evolution, manifested in significant topography and reversed drainages networks. Consequently, the UNW, including Lakes Albert, Edward, Victoria, and Kyoga, and their riverine connections, provide an important case study for drainage basin evolution in actively extending continental lithosphere. In addition to multiple scales of tectonic deformation, high frequency climate change affects the basins in the UNW, which record moisture signals from both the Indian and Atlantic Oceans. Paleoclimate proxy data indicate the desiccation of Lake Victoria and cessation of Victoria Nile flow during the Last Glacial Maximum (22 - 18 ka). However, the response of Lakes Albert and Edward during this time period is not fully resolved. In 2003, 1600 line km of multichannel seismic reflection and high resolution echo-sounder data were collected from Lake Albert, while 200 km of 1 kHz seismic reflection data were collected from Lake Edward. In conjunction with recently released digital elevation models, we investigate both tectonic and climatic processes operative in the basins. In Lake Albert, we are able to map depth to pre-rift basement, basin boundary fault as well as intrabasinal fault geometries that control both bathymetry and sediment distribution. Shallow reflections suggest desiccation of the lake, probably during the LGM; these results tie well with published sediment core data. Acoustic data from Lake Edward record two regression events, although this lake apparently escaped LGM desiccation, and may contain a complete, high-resolution archive of Quaternary climate change in its deep-water sequences. Our interpretations provide another

  12. Suitability of using diffusive gradients in thin films (DGT) to study metal bioavailability in mine tailings: possibilities and constraints.

    PubMed

    Conesa, Héctor Miguel; Schulin, Rainer; Nowack, Bernd

    2010-03-01

    Diffusive gradients in thin films (DGT) have been recognized as a suitable tool to assess in situ metal bioavailability in soils. Mine tailings have some singular characteristics such as high heavy-metal concentrations, low pH, or absence of water retention capacity that may compromise the correct application of this technique whose applicability is known to be pH dependent. The goal of this study was to determine the response of DGT devices in heavy-metal-polluted mine tailings with different pH. In addition some experiments were performed in order to determine the effect of acidic pH and dissolved ions on the binding properties of the chelating resin. We tested DGT devices on three different mine tailings: acid pH 3, acid tailing limed to pH 5.5, and neutral pH 7.2. The tailings showed high metal concentrations, e.g., 7,000 mg kg(-1) Pb, 9,000 mg kg(-1) Zn, and 380 mg kg(-1) Cu. Diffusive and Chelex resin gels were prepared according to previously published methods. Two chelating resins and diffusive gels thicknesses (0.4 and 0.7 mm) were tested. Four DGT devices of each type were placed during 24 h in pots (one device per pot) containing 1 kg mine tailings in a climate chamber with humidity (50-90%) and controlled temperature conditions (night 16 degrees C and day 23 degrees C). Pots were irrigated with deionized water to field capacity, and then two different experiments were performed: (a) allowing free drainage and (b) maintaining the water saturation. In addition, we tested DGT devices in solutions at pH 3 with similar properties to the soil solution measured in the acid tailing. Eluted Zn, Cd, Pb, and Cu from the chelating resins were measured using inductively coupled plasma-optical emission spectrometer (ICP-OES; Vista-MPX Varian). The metal concentrations taken up by the DGT devices were affected by the different pH values of the tailings. The highest metal concentrations measured with DGT (C (DGT)) were obtained in the pH 3 treatments (both saturated

  13. Structure Constraints in a Constraint-Based Planner

    NASA Technical Reports Server (NTRS)

    Pang, Wan-Lin; Golden, Keith

    2004-01-01

    In this paper we report our work on a new constraint domain, where variables can take structured values. Earth-science data processing (ESDP) is a planning domain that requires the ability to represent and reason about complex constraints over structured data, such as satellite images. This paper reports on a constraint-based planner for ESDP and similar domains. We discuss our approach for translating a planning problem into a constraint satisfaction problem (CSP) and for representing and reasoning about structured objects and constraints over structures.

  14. REDUCTION OF CONSTRAINTS FOR COUPLED OPERATIONS

    SciTech Connect

    Raszewski, F.; Edwards, T.

    2009-12-15

    The homogeneity constraint was implemented in the Defense Waste Processing Facility (DWPF) Product Composition Control System (PCCS) to help ensure that the current durability models would be applicable to the glass compositions being processed during DWPF operations. While the homogeneity constraint is typically an issue at lower waste loadings (WLs), it may impact the operating windows for DWPF operations, where the glass forming systems may be limited to lower waste loadings based on fissile or heat load limits. In the sludge batch 1b (SB1b) variability study, application of the homogeneity constraint at the measurement acceptability region (MAR) limit eliminated much of the potential operating window for DWPF. As a result, Edwards and Brown developed criteria that allowed DWPF to relax the homogeneity constraint from the MAR to the property acceptance region (PAR) criterion, which opened up the operating window for DWPF operations. These criteria are defined as: (1) use the alumina constraint as currently implemented in PCCS (Al{sub 2}O{sub 3} {ge} 3 wt%) and add a sum of alkali constraint with an upper limit of 19.3 wt% ({Sigma}M{sub 2}O < 19.3 wt%), or (2) adjust the lower limit on the Al{sub 2}O{sub 3} constraint to 4 wt% (Al{sub 2}O{sub 3} {ge} 4 wt%). Herman et al. previously demonstrated that these criteria could be used to replace the homogeneity constraint for future sludge-only batches. The compositional region encompassing coupled operations flowsheets could not be bounded as these flowsheets were unknown at the time. With the initiation of coupled operations at DWPF in 2008, the need to revisit the homogeneity constraint was realized. This constraint was specifically addressed through the variability study for SB5 where it was shown that the homogeneity constraint could be ignored if the alumina and alkali constraints were imposed. Additional benefit could be gained if the homogeneity constraint could be replaced by the Al{sub 2}O{sub 3} and sum of

  15. Using formative assessment despite the constraints of high stakes testing and limited resources: A case study of chemistry teachers in Anglophone Cameroon

    NASA Astrophysics Data System (ADS)

    Akom, George Viche

    Formative assessment, as a strategy used to improve student learning, encounters several obstacles in its implementation. This study explores changes in teachers' views and practices as they are introduced to formative assessment in a high stakes testing and limited resource environment. The study examines the extent to which teachers use the technique of formative assessment to engage students in authentic learning even while not sacrificing high test scores on summative assessments. A case study methodology was employed to address the research topic. Science teachers in the West African country of Cameroon were engaged in a process of lesson planning and implementation to collaboratively build lessons with large amounts of formative assessment. Qualitative data from written surveys, group discussions, classroom and workshop observations, and from teacher reflections reveal the extent to which lesson fidelity is preserved from views to planning to implementation. The findings revealed that though the teachers possess knowledge of a variety of assessment methods they do not systematically use these methods to collect information which could help in improving student learning. Oral questioning remained the dominant method of student assessment. The study also showed that the teachers made minimal to big changes depending on the particular aspect of formative assessment being considered. For aspects which needed just behavioral adaptations, the changes were significant but for those which needed acquisition of more pedagogic knowledge and skills the changes were minimal. In terms of constraints in the practice of formative assessment, the teachers cited large class size and lack of teaching materials as common ones. When provided with the opportunity to acquire teaching materials, however, they did not effectively utilize the opportunity. The study revealed a need for the acquisition of inquiry skills by the teachers which can serve as a platform for the

  16. Multi-scale constraints of sediment source to sink systems in frontier basins: a forward stratigraphic modeling case study of the Levant region

    NASA Astrophysics Data System (ADS)

    Hawie, Nicolas; Deschamps, Remy; Granjeon, Didier; Nader, Fadi-Henri; Gorini, Christian; Müller, Carla; Montadert, Lucien; Baudin, François

    2015-04-01

    Recent scientific work underlined the presence of a thick Cenozoic infill in the Levant Basin reaching up to 12 km. Interestingly; restricted sedimentation was observed along the Levant margin in the Cenozoic. Since the Late Eocene successive regional geodynamic events affecting Afro-Arabia and Eurasia (collision and strike slip deformation)induced fast marginal uplifts. The initiation of local and long-lived regional drainage systems in the Oligo-Miocene period (e.g. Lebanon versus Nile) provoked a change in the depositional pattern along the Levant margin and basin. A shift from carbonate dominated environments into clastic rich systems has been observed. Through this communication we explore the importance of multi-scale constraints (i.e.,seismic, well and field data) in the quantification of the subsidence history, sediment transport and deposition of a Middle-Upper Miocene "multi-source" to sink system along the northernLevant frontier region. We prove through a comprehensive forward stratigraphic modeling workflow that the contribution to the infill of the northern Levant Basin (offshore Lebanon) is split in between proximal and more distal clastic sources as well as in situ carbonate/hemipelagic deposition. In a wider perspective this work falls under the umbrella of multi-disciplinary source to sink studies that investigate the impact of geodynamic events on basin/margin architectural evolutions, consequent sedimentary infill and thus on petroleum systems assessment.

  17. Mars, Always Cold, Sometimes Wet: New Constraints on Mars Denudation Rates and Climate Evolution from Analog Studies at Haughton Crater, Devon Island, High Arctic

    NASA Technical Reports Server (NTRS)

    Lee, Pascal; Boucher, M.; Desportes, C.; Glass, B. J.; Lim, D.; McKay, C. P.; Osinski, G. R.; Parnell, J.; Schutt, J. W.

    2005-01-01

    Analysis of crater modification on Mars and at Haughton Crater, Devon Island, High Arctic, which was recently shown to be significantly older than previously believed (Eocene age instead of Miocene) [1], suggest that Mars may have never been climatically wet and warm for geological lengths of time during and since the Late Noachian. Impact structures offer particularly valuable records of the evolution of a planet s climate and landscape through time. The state of exposure and preservation of impact structures and their intracrater fill provide clues to the nature, timing, and intensity of the processes that have modified the craters since their formation. Modifying processes include weathering, erosion, mantling, and infilling. In this study, we compare the modification of Haughton through time with that of impact craters in the same size class on Mars. We derive upper limits for time-integrated denudation rates on Mars during and since the Late Noachian. These rates are significantly lower than previously published and provide important constraints for Mars climate evolution.

  18. Physiological constraints and energetic costs of diving behaviour in marine mammals: a review of studies using trained Steller sea lions diving in the open ocean.

    PubMed

    Rosen, David A S; Hindle, Allyson G; Gerlinsky, Carling D; Goundie, Elizabeth; Hastie, Gordon D; Volpov, Beth L; Trites, Andrew W

    2017-01-01

    Marine mammals are characterized as having physiological specializations that maximize the use of oxygen stores to prolong time spent under water. However, it has been difficult to undertake the requisite controlled studies to determine the physiological limitations and trade-offs that marine mammals face while diving in the wild under varying environmental and nutritional conditions. For the past decade, Steller sea lions (Eumetopias jubatus) trained to swim and dive in the open ocean away from the physical confines of pools participated in studies that investigated the interactions between diving behaviour, energetic costs, physiological constraints, and prey availability. Many of these studies measured the cost of diving to understand how it varies with behaviour and environmental and physiological conditions. Collectively, these studies show that the type of diving (dive bouts or single dives), the level of underwater activity, the depth and duration of dives, and the nutritional status and physical condition of the animal affect the cost of diving and foraging. They show that dive depth, dive and surface duration, and the type of dive result in physiological adjustments (heart rate, gas exchange) that may be independent of energy expenditure. They also demonstrate that changes in prey abundance and nutritional status cause sea lions to alter the balance between time spent at the surface acquiring oxygen (and offloading CO2 and other metabolic by-products) and time spent at depth acquiring prey. These new insights into the physiological basis of diving behaviour further our understanding of the potential scope for behavioural responses of marine mammals to environmental changes, the energetic significance of these adjustments, and the consequences of approaching physiological limits.

  19. Integrated Analysis of Airport Capacity and Environmental Constraints

    NASA Technical Reports Server (NTRS)

    Hasan, Shahab; Long, Dou; Hart, George; Eckhause, Jeremy; Hemm, Robert; Busick, Andrew; Graham, Michael; Thompson, Terry; Murphy, Charles; Poage, James

    2010-01-01

    LMI conducted an integrated analysis of airport capacity and environmental constraints. identifying and ranking the key factors limiting achievement of NextGen capacity goals. The primary metric used was projected throughput, which was estimated for the years 2015 and 2025 based on the unconstrained demand forecast from the Federal Aviation Administration, and planned improvements including those proposed in the NextGen plan. A set of 310 critical airports was identified.. collectively accounting for more than 99 percent of domestic air traffic volume; a one-off analytical approach was used to isolate the constraint being assessed. The study considered three capacity constraints (runway.. taxiway, and gate) and three environmental constraints (fuel, NO(x) emissions, and noise). For the ten busiest airports, runway and noise are the primary and secondary constraints in both 2015 and 2025. For the OEP 35 airports and overall for the remaining airports, the most binding constraint is noise. Six of the 10 busiest airports, will face runway constraints in 2025, and 95 will face gate constraints. Nearly every airport will be subject to constraints due to emissions and NOx. Runway and taxi constraints are more concentrated in the large airports: environmental constraints are present at almost every airport regardless of size.

  20. Practical Cleanroom Operations Constraints

    NASA Technical Reports Server (NTRS)

    Hughes, David; Ginyard, Amani

    2007-01-01

    This viewgraph presentation reviews the GSFC Cleanroom Facility i.e., Spacecraft Systems Development and Integration Facility (SSDIF) with particular interest in its use during the development of the Wide Field Camera 3 (WFC3). The SSDIF is described and a diagram of the SSDIF is shown. A Constraint Table was created for consistency within Contamination Control Team. This table is shown. Another table that shows the activities that were allowed during the integration under given WFC3 condition and activity location is presented. Three decision trees are shown for different phases of the work: (1) Hardware Relocation, Hardware Work, and Contamination Control Operations.

  1. Effect of therapist-based constraint-induced therapy at home on motor control, motor performance and daily function in children with cerebral palsy: a randomized controlled study.

    PubMed

    Chen, Chia-ling; Kang, Lin-ju; Hong, Wei-Hsien; Chen, Fei-Chuan; Chen, Hsieh-Ching; Wu, Ching-yi

    2013-03-01

    To determine the effect of therapist-based constraint-induced therapy at home on motor performance, daily function and reaching control for children with cerebral palsy. A single-blinded, randomized controlled trial. Forty-seven children (23 boys; 24 girls) with unilateral cerebral palsy, aged 6-12 years, were randomized to constraint-induced therapy (n = 24) or traditional rehabilitation (n = 23). Constraint-induced therapy involved intensive functional training of the more affected arm while the less affected arm was restrained. Traditional rehabilitation involved functional unilateral and bilateral arm training. Both groups received individualized therapist-based interventions at home for 3.5-4 hours/day, two days a week for four weeks. Motor performance and daily function were measured by the Peabody Developmental Motor Scale, Second Edition and the Pediatric Motor Activity Log. Reaching control was assessed by the kinematics of reaction time, movement time, movement unit and peak velocity. There were larger effects in favour of constraint-induced therapy on motor performance, daily function, and some aspects of reaching control compared with traditional rehabilitation. Children receiving constraint-induced therapy demonstrated higher scores for Peabody Developmental Motor Scale, Second Edition - Grasping (pretest mean ± SD, 39.9 ± 3.1; posttest, 44.1 ± 2.8; P < 0.001), Pediatric Motor Activity Log (pretest, 1.8 ± 0.3; posttest, 2.5 ± 0.3; P < 0.001) and shorter reaction time, normalized movement time (P < 0.001) and higher peak velocity (P = 0.004) of reaching movement. Constraint-induced therapy induced better grasping performance, daily function, and temporal and spatiotemporal control of reaching in children with unilateral cerebral palsy than traditional rehabilitation.

  2. Symbolic Constraint Maintenance Grid

    NASA Technical Reports Server (NTRS)

    James, Mark

    2006-01-01

    Version 3.1 of Symbolic Constraint Maintenance Grid (SCMG) is a software system that provides a general conceptual framework for utilizing pre-existing programming techniques to perform symbolic transformations of data. SCMG also provides a language (and an associated communication method and protocol) for representing constraints on the original non-symbolic data. SCMG provides a facility for exchanging information between numeric and symbolic components without knowing the details of the components themselves. In essence, it integrates symbolic software tools (for diagnosis, prognosis, and planning) with non-artificial-intelligence software. SCMG executes a process of symbolic summarization and monitoring of continuous time series data that are being abstractly represented as symbolic templates of information exchange. This summarization process enables such symbolic- reasoning computing systems as artificial- intelligence planning systems to evaluate the significance and effects of channels of data more efficiently than would otherwise be possible. As a result of the increased efficiency in representation, reasoning software can monitor more channels and is thus able to perform monitoring and control functions more effectively.

  3. Reduction of Constraints: Applicability of the Homogeneity Constraint for Macrobatch 3

    SciTech Connect

    Peeler, D.K.

    2001-02-15

    The Product Composition Control System (PCCS) is used to determine the acceptability of each batch of Defense Waste Processing Facility (DWPF) melter feed in the Slurry Mix Evaporator (SME). This control system imposes several constraints on the composition of the contents of the SME to define acceptability. These constraints relate process or product properties to composition via prediction models. A SME batch is deemed acceptable if its sample composition measurements lead to acceptable property predictions after accounting for modeling, measurement and analytic uncertainties. The baseline document guiding the use of these data and models is ''SME Acceptability Determination for DWPF Process Control (U)'' by Brown and Postles [1996]. A minimum of three PCCS constraints support the prediction of the glass durability from a given SME batch. The Savannah River Technology Center (SRTC) is reviewing all of the PCCS constraints associated with durability. The purpose of this review is to revisit these constraints in light of the additional knowledge gained since the beginning of radioactive operations at DWPF and to identify any supplemental studies needed to amplify this knowledge so that redundant or overly conservative constraints can be eliminated or replaced by more appropriate constraints.

  4. Inferring Broad Regulatory Biology from Time Course Data: Have We Reached an Upper Bound under Constraints Typical of In Vivo Studies?

    PubMed Central

    Craddock, Travis J. A.; Fletcher, Mary Ann; Klimas, Nancy G.

    2015-01-01

    There is a growing appreciation for the network biology that regulates the coordinated expression of molecular and cellular markers however questions persist regarding the identifiability of these networks. Here we explore some of the issues relevant to recovering directed regulatory networks from time course data collected under experimental constraints typical of in vivo studies. NetSim simulations of sparsely connected biological networks were used to evaluate two simple feature selection techniques used in the construction of linear Ordinary Differential Equation (ODE) models, namely truncation of terms versus latent vector projection. Performance was compared with ODE-based Time Series Network Identification (TSNI) integral, and the information-theoretic Time-Delay ARACNE (TD-ARACNE). Projection-based techniques and TSNI integral outperformed truncation-based selection and TD-ARACNE on aggregate networks with edge densities of 10-30%, i.e. transcription factor, protein-protein cliques and immune signaling networks. All were more robust to noise than truncation-based feature selection. Performance was comparable on the in silico 10-node DREAM 3 network, a 5-node Yeast synthetic network designed for In vivo Reverse-engineering and Modeling Assessment (IRMA) and a 9-node human HeLa cell cycle network of similar size and edge density. Performance was more sensitive to the number of time courses than to sample frequency and extrapolated better to larger networks by grouping experiments. In all cases performance declined rapidly in larger networks with lower edge density. Limited recovery and high false positive rates obtained overall bring into question our ability to generate informative time course data rather than the design of any particular reverse engineering algorithm. PMID:25984725

  5. The neural correlates of biomechanical constraints in hand laterality judgment task performed from other person's perspective: A near-infrared spectroscopy study.

    PubMed

    Meng, Shuang; Oi, Misato; Saito, Godai; Saito, Hirofumi

    2017-01-01

    Previous studies, mainly using a first-person perspective (1PP), have shown that the judgments of the hand laterality judgment (HLJ) task are dependent on biomechanical constraints (BC). Specifically, differing reaction times (RT) for hand pictures rotated medially or laterally around the mid sagittal plane are attributed to the BC effect on motor imagery. In contrast, we investigated whether the HLJ task is also subject to BC when performed from a third-person perspective (3PP) as well as 1PP using near-infrared spectroscopy (NIRS) to measure the brain activity of prefrontal cortex (PFC) in right-handed participants assigned to 1PP or 3PP groups. The 1PP group judged whether a presented hand was their own left or right hand, and the 3PP group whether it was the other's left or right hand. Using their HLJ task error rates, the 1PP and 3PP groups were subdivided into an Error Group (EG) and No Error Group (NEG). For the 1PP group, both EG and NEG showed a significant Hand Laterality × Orientation interaction for RT, indicating the BC effect on motor imagery. For the 3PP group, however, neither EG nor NEG showed the interaction, even though EG showed a significantly longer RT than NEG. These results suggest that the 3PP EG appropriately followed the 3PP task instruction, while the NEG might have taken 1PP. However, the 3PP EG NIRS profile of left PFC showed a significant Hand Laterality × Orientation interaction, while the 1PP EG did not. More noteworthy is that the left PFC activation of EG showed an interaction between the 1PP and 3PP groups when the left hand was presented. Furthermore, in the NEG, the PFC activation was not influenced by the BC in either the 1PP or 3PP condition. These results indicate that BC interferes with the HLJ task performed from the 1PP and 3PP.

  6. Inferring Broad Regulatory Biology from Time Course Data: Have We Reached an Upper Bound under Constraints Typical of In Vivo Studies?

    PubMed

    Vashishtha, Saurabh; Broderick, Gordon; Craddock, Travis J A; Fletcher, Mary Ann; Klimas, Nancy G

    2015-01-01

    There is a growing appreciation for the network biology that regulates the coordinated expression of molecular and cellular markers however questions persist regarding the identifiability of these networks. Here we explore some of the issues relevant to recovering directed regulatory networks from time course data collected under experimental constraints typical of in vivo studies. NetSim simulations of sparsely connected biological networks were used to evaluate two simple feature selection techniques used in the construction of linear Ordinary Differential Equation (ODE) models, namely truncation of terms versus latent vector projection. Performance was compared with ODE-based Time Series Network Identification (TSNI) integral, and the information-theoretic Time-Delay ARACNE (TD-ARACNE). Projection-based techniques and TSNI integral outperformed truncation-based selection and TD-ARACNE on aggregate networks with edge densities of 10-30%, i.e. transcription factor, protein-protein cliques and immune signaling networks. All were more robust to noise than truncation-based feature selection. Performance was comparable on the in silico 10-node DREAM 3 network, a 5-node Yeast synthetic network designed for In vivo Reverse-engineering and Modeling Assessment (IRMA) and a 9-node human HeLa cell cycle network of similar size and edge density. Performance was more sensitive to the number of time courses than to sample frequency and extrapolated better to larger networks by grouping experiments. In all cases performance declined rapidly in larger networks with lower edge density. Limited recovery and high false positive rates obtained overall bring into question our ability to generate informative time course data rather than the design of any particular reverse engineering algorithm.

  7. Effects of three-dimensional crustal structure and smoothing constraint on earthquake slip inversions: Case study of the Mw6.3 2009 L'Aquila earthquake

    NASA Astrophysics Data System (ADS)

    Gallovič, František; Imperatori, Walter; Mai, P. Martin

    2015-01-01

    Earthquake slip inversions aiming to retrieve kinematic rupture characteristics typically assume 1-D velocity models and a flat Earth surface. However, heterogeneous nature of the crust and presence of rough topography lead to seismic scattering and other wave propagation phenomena, introducing complex 3-D effects on ground motions. Here we investigate how the use of imprecise Green's functions—achieved by including 3-D velocity perturbations and topography—affect slip-inversion results. We create sets of synthetic seismograms, including 3-D heterogeneous Earth structure and topography, and then invert these synthetics using Green's functions computed for a horizontally layered 1-D Earth model. We apply a linear inversion, regularized by smoothing and positivity constraint, and examine in detail how smoothing effects perturb the solution. Among others, our tests and resolution analyses demonstrate how imprecise Green's functions introduce artificial slip rate multiples especially at shallow depths and that the timing of the peak slip rate is hardly affected by the chosen smoothing. The investigation is extended to recordings of the 2009 Mw6.3 L'Aquila earthquake, considering both strong motion and high-rate GPS stations. We interpret the inversion results taking into account the lessons learned from the synthetic tests. The retrieved slip model resembles previously published solutions using geodetic data, showing a large-slip asperity southeast of the hypocenter. In agreement with other studies, we find evidence for fast but subshear rupture propagation in updip direction, followed by a delayed propagation along strike. We conjecture that rupture was partially inhibited by a deep localized velocity-strengthening patch that subsequently experienced afterslip.

  8. Toward a theory of constraints.

    PubMed

    Breunlin, D C

    1999-06-01

    Grounded in the cybernetic concept of negative explanation, the theory of constraints examines how human systems are kept from solving problems. To identify constraints, therapists must know where to look for them and what to look for. The theory proposes that constraints exist among the levels of a biopsychosocial system, which include biology, person, relationship, family, community, and society. The six metaframeworks of organization, sequences, mind, development, gender, and culture assist constraint identification. Combining the levels and metaframeworks creates a web of constraints, the complexity of which determines how difficult it will be to solve a given problem. The theory of constraint offers an integrative and pragmatic approach to therapy while simultaneously honoring the complexity of human systems.

  9. The effects of perceived leisure constraints among Korean university students

    Treesearch

    Sae-Sook Oh; Sei-Yi Oh; Linda L. Caldwell

    2002-01-01

    This study is based on Crawford, Jackson, and Godbey's model of leisure constraints (1991), and examines the relationships between the influences of perceived constraints, frequency of participation, and health status in the context of leisure-time outdoor activities. The study was based on a sample of 234 Korean university students. This study provides further...

  10. Relative constraints and evolution

    NASA Astrophysics Data System (ADS)

    Ochoa, Juan G. Diaz

    2014-03-01

    Several mathematical models of evolving systems assume that changes in the micro-states are constrained to the search of an optimal value in a local or global objective function. However, the concept of evolution requires a continuous change in the environment and species, making difficult the definition of absolute optimal values in objective functions. In this paper, we define constraints that are not absolute but relative to local micro-states, introducing a rupture in the invariance of the phase space of the system. This conceptual basis is useful to define alternative mathematical models for biological (or in general complex) evolving systems. We illustrate this concept with a modified Ising model, which can be useful to understand and model problems like the somatic evolution of cancer.

  11. Dynamical aspects of behavior generation under constraints

    PubMed Central

    Harter, Derek; Achunala, Srinivas

    2007-01-01

    Dynamic adaptation is a key feature of brains helping to maintain the quality of their performance in the face of increasingly difficult constraints. How to achieve high-quality performance under demanding real-time conditions is an important question in the study of cognitive behaviors. Animals and humans are embedded in and constrained by their environments. Our goal is to improve the understanding of the dynamics of the interacting brain–environment system by studying human behaviors when completing constrained tasks and by modeling the observed behavior. In this article we present results of experiments with humans performing tasks on the computer under variable time and resource constraints. We compare various models of behavior generation in order to describe the observed human performance. Finally we speculate on mechanisms how chaotic neurodynamics can contribute to the generation of flexible human behaviors under constraints. PMID:19003514

  12. Neural constraints on learning.

    PubMed

    Sadtler, Patrick T; Quick, Kristin M; Golub, Matthew D; Chase, Steven M; Ryu, Stephen I; Tyler-Kabara, Elizabeth C; Yu, Byron M; Batista, Aaron P

    2014-08-28

    Learning, whether motor, sensory or cognitive, requires networks of neurons to generate new activity patterns. As some behaviours are easier to learn than others, we asked if some neural activity patterns are easier to generate than others. Here we investigate whether an existing network constrains the patterns that a subset of its neurons is capable of exhibiting, and if so, what principles define this constraint. We employed a closed-loop intracortical brain-computer interface learning paradigm in which Rhesus macaques (Macaca mulatta) controlled a computer cursor by modulating neural activity patterns in the primary motor cortex. Using the brain-computer interface paradigm, we could specify and alter how neural activity mapped to cursor velocity. At the start of each session, we observed the characteristic activity patterns of the recorded neural population. The activity of a neural population can be represented in a high-dimensional space (termed the neural space), wherein each dimension corresponds to the activity of one neuron. These characteristic activity patterns comprise a low-dimensional subspace (termed the intrinsic manifold) within the neural space. The intrinsic manifold presumably reflects constraints imposed by the underlying neural circuitry. Here we show that the animals could readily learn to proficiently control the cursor using neural activity patterns that were within the intrinsic manifold. However, animals were less able to learn to proficiently control the cursor using activity patterns that were outside of the intrinsic manifold. These results suggest that the existing structure of a network can shape learning. On a timescale of hours, it seems to be difficult to learn to generate neural activity patterns that are not consistent with the existing network structure. These findings offer a network-level explanation for the observation that we are more readily able to learn new skills when they are related to the skills that we already

  13. Neural constraints on learning

    PubMed Central

    Sadtler, Patrick T.; Quick, Kristin M.; Golub, Matthew D.; Chase, Steven M.; Ryu, Stephen I.; Tyler-Kabara, Elizabeth C.; Yu, Byron M.; Batista, Aaron P.

    2014-01-01

    Motor, sensory, and cognitive learning require networks of neurons to generate new activity patterns. Because some behaviors are easier to learn than others1,2, we wondered if some neural activity patterns are easier to generate than others. We asked whether the existing network constrains the patterns that a subset of its neurons is capable of exhibiting, and if so, what principles define the constraint. We employed a closed-loop intracortical brain-computer interface (BCI) learning paradigm in which Rhesus monkeys controlled a computer cursor by modulating neural activity patterns in primary motor cortex. Using the BCI paradigm, we could specify and alter how neural activity mapped to cursor velocity. At the start of each session, we observed the characteristic activity patterns of the recorded neural population. These patterns comprise a low-dimensional space (termed the intrinsic manifold, or IM) within the high-dimensional neural firing rate space. They presumably reflect constraints imposed by the underlying neural circuitry. We found that the animals could readily learn to proficiently control the cursor using neural activity patterns that were within the IM. However, animals were less able to learn to proficiently control the cursor using activity patterns that were outside of the IM. This result suggests that the existing structure of a network can shape learning. On the timescale of hours, it appears to be difficult to learn to generate neural activity patterns that are not consistent with the existing network structure. These findings offer a network-level explanation for the observation that we are more readily able to learn new skills when they are related to the skills that we already possess3,4. PMID:25164754

  14. Robust Utility Maximization Under Convex Portfolio Constraints

    SciTech Connect

    Matoussi, Anis; Mezghani, Hanen Mnif, Mohamed

    2015-04-15

    We study a robust maximization problem from terminal wealth and consumption under a convex constraints on the portfolio. We state the existence and the uniqueness of the consumption–investment strategy by studying the associated quadratic backward stochastic differential equation. We characterize the optimal control by using the duality method and deriving a dynamic maximum principle.

  15. The Approximability of Learning and Constraint Satisfaction Problems

    DTIC Science & Technology

    2010-10-07

    The Approximability of Learning and Constraint Satisfaction Problems Yi Wu CMU-CS-10-142 October 7, 2010 School of Computer Science Carnegie Mellon...00-00-2010 to 00-00-2010 4. TITLE AND SUBTITLE The Approximability of Learning and Constraint Satisfaction Problems 5a. CONTRACT NUMBER 5b...approximability of two classes of NP-hard problems: Constraint Satisfaction Problems (CSPs) and Computational Learning Problems. For CSPs, we mainly study the

  16. Safety and environmental constraints on space applications of fusion energy

    NASA Technical Reports Server (NTRS)

    Roth, J. Reece

    1990-01-01

    Some of the constraints are examined on fusion reactions, plasma confinement systems, and fusion reactors that are intended for such space related missions as manned or unmanned operations in near earth orbit, interplanetary missions, or requirements of the SDI program. Of the many constraints on space power and propulsion systems, those arising from safety and environmental considerations are emphasized since these considerations place severe constraints on some fusion systems and have not been adequately treated in previous studies.

  17. Topological Constraints in Directed Polymer Melts.

    PubMed

    Serna, Pablo; Bunin, Guy; Nahum, Adam

    2015-11-27

    Polymers in a melt may be subject to topological constraints, as in the example of unlinked polymer rings. How to do statistical mechanics in the presence of such constraints remains a fundamental open problem. We study the effect of topological constraints on a melt of directed polymers, using simulations of a simple quasi-2D model. We find that fixing the global topology of the melt to be trivial changes the polymer conformations drastically. Polymers of length L wander in the transverse direction only by a distance of order (lnL)^{ζ} with ζ≃1.5. This is strongly suppressed in comparison with the Brownian L^{1/2} scaling which holds in the absence of the topological constraint. It is also much smaller than the predictions of standard heuristic approaches-in particular the L^{1/4} of a mean-field-like "array of obstacles" model-so our results present a sharp challenge to theory. Dynamics are also strongly affected by the constraints, and a tagged monomer in an infinite system performs logarithmically slow subdiffusion in the transverse direction. To cast light on the suppression of the strands' wandering, we analyze the topological complexity of subregions of the melt: the complexity is also logarithmically small, and is related to the wandering by a power law. We comment on insights the results give for 3D melts, directed and nondirected.

  18. Constraints and spandrels of interareal connectomes

    NASA Astrophysics Data System (ADS)

    Rubinov, Mikail

    2016-12-01

    Interareal connectomes are whole-brain wiring diagrams of white-matter pathways. Recent studies have identified modules, hubs, module hierarchies and rich clubs as structural hallmarks of these wiring diagrams. An influential current theory postulates that connectome modules are adequately explained by evolutionary pressures for wiring economy, but that the other hallmarks are not explained by such pressures and are therefore less trivial. Here, we use constraint network models to test these postulates in current gold-standard vertebrate and invertebrate interareal-connectome reconstructions. We show that empirical wiring-cost constraints inadequately explain connectome module organization, and that simultaneous module and hub constraints induce the structural byproducts of hierarchies and rich clubs. These byproducts, known as spandrels in evolutionary biology, include the structural substrate of the default-mode network. Our results imply that currently standard connectome characterizations are based on circular analyses or double dipping, and we emphasize an integrative approach to future connectome analyses for avoiding such pitfalls.

  19. Inference-based constraint satisfaction supports explanation

    SciTech Connect

    Sqalli, M.H.; Freuder, E.C.

    1996-12-31

    Constraint satisfaction problems are typically solved using search, augmented by general purpose consistency inference methods. This paper proposes a paradigm shift in which inference is used as the primary problem solving method, and attention is focused on special purpose, domain specific inference methods. While we expect this approach to have computational advantages, we emphasize here the advantages of a solution method that is more congenial to human thought processes. Specifically we use inference-based constraint satisfaction to support explanations of the problem solving behavior that are considerably more meaningful than a trace of a search process would be. Logic puzzles are used as a case study. Inference-based constraint satisfaction proves surprisingly powerful and easily extensible in this domain. Problems drawn from commercial logic puzzle booklets are used for evaluation. Explanations are produced that compare well with the explanations provided by these booklets.

  20. Propagating Resource Constraints Using Mutual Exclusion Reasoning

    NASA Technical Reports Server (NTRS)

    Frank, Jeremy; Sanchez, Romeo; Do, Minh B.; Clancy, Daniel (Technical Monitor)

    2001-01-01

    One of the most recent techniques for propagating resource constraints in Constraint Based scheduling is Energy Constraint. This technique focuses in precedence based scheduling, where precedence relations are taken into account rather than the absolute position of activities. Although, this particular technique proved to be efficient on discrete unary resources, it provides only loose bounds for jobs using discrete multi-capacity resources. In this paper we show how mutual exclusion reasoning can be used to propagate time bounds for activities using discrete resources. We show that our technique based on critical path analysis and mutex reasoning is just as effective on unary resources, and also shows that it is more effective on multi-capacity resources, through both examples and empirical study.

  1. General constraints on the Viking biology investigation

    NASA Technical Reports Server (NTRS)

    Klein, H. P.

    1976-01-01

    The paper discusses some of the constraints pertaining to the Viking mission for detection of life on Mars, within which the Viking experiments were conceived, designed, and developed. The most important limitation to the entire study is the complete information about the nature of Mars, such as the chemical composition of the surface material of Mars and the exact identification of the constituents of that planet. Ways in which celestial mechanics places severe limitations on the Viking biology investigation are discussed. Major engineering constraints are examined relative to the accomodation of biology instrument inside the Viking lander and to the design of the instrument itself. Other constraints discussed concern the operational aspects of the mission and the testing program.

  2. q-Virasoro constraints in matrix models

    NASA Astrophysics Data System (ADS)

    Nedelin, Anton; Zabzine, Maxim

    2017-03-01

    The Virasoro constraints play the important role in the study of matrix models and in understanding of the relation between matrix models and CFTs. Recently the localization calculations in supersymmetric gauge theories produced new families of matrix models and we have very limited knowledge about these matrix models. We concentrate on elliptic generalization of hermitian matrix model which corresponds to calculation of partition function on S 3 × S 1 for vector multiplet. We derive the q-Virasoro constraints for this matrix model. We also observe some interesting algebraic properties of the q-Virasoro algebra.

  3. Constraints on extra dimensions from atomic spectroscopy

    NASA Astrophysics Data System (ADS)

    Dahia, F.; Lemos, A. S.

    2016-10-01

    We consider a hydrogen atom confined in a thick brane embedded in a higher-dimensional space. Due to effects of the extra dimensions, the gravitational potential is amplified in distances smaller than the size of the supplementary space, in comparison with the Newtonian potential. Studying the influence of the gravitational interaction modified by the extra dimensions on the energy levels of the hydrogen atom, we find independent constraints for the higher-dimensional Planck mass in terms of the thickness of the brane by using accurate measurements of atomic transition frequencies. The constraints are very stringent for narrow branes.

  4. A study of the impacts of flow direction and electrical constraints on vulnerability assessment of power grid using electrical betweenness measures

    NASA Astrophysics Data System (ADS)

    Wu, Di; Ma, Feng; Javadi, Milad; Thulasiraman, Krishnaiya; Bompard, Ettore; Jiang, John N.

    2017-01-01

    In this paper, we analyze the impacts of major electrical properties, including node constraints, line limits, and flow direction, on vulnerability assessment of power grid using several types of electrical betweenness measures. Specifically, we first propose a set of new electrical betweenness measures, which takes into account flow direction in power grids. Then, the impacts of major electrical properties on vulnerability assessment of power grid are analyzed by comparing the identification results of critical components based on the proposed electrical betweenness measures with those based on the other two types of electrical betweenness measures reported in the literature, which take into consideration node constraints and line limits, respectively. Analysis results show the important impact of flow direction on the identification of critical components. The results lead us to introduce a set of combined electrical betweenness measures that take into account node constraints, line limits, and flow direction together. Simulation results on the IEEE 300-bus system and the Italian power grid show that the combined electrical betweenness measures are superior in identifying critical components and more useful in assessing power grid vulnerability.

  5. Constraint Ornstein-Uhlenbeck bridges

    NASA Astrophysics Data System (ADS)

    Mazzolo, Alain

    2017-09-01

    In this paper, we study the Ornstein-Uhlenbeck bridge process (i.e., the Ornstein-Uhlenbeck process conditioned to start and end at fixed points) constraints to have a fixed area under its path. We present both anticipative (in this case, we need the knowledge of the future of the path) and non-anticipative versions of the stochastic process. We obtain the anticipative description thanks to the theory of generalized Gaussian bridges while the non-anticipative representation comes from the theory of stochastic control. For this last representation, a stochastic differential equation is derived which leads to an effective Langevin equation. Finally, we extend our theoretical findings to linear bridge processes.

  6. Observational constraints on Galileon cosmology

    NASA Astrophysics Data System (ADS)

    Nesseris, Savvas; de Felice, Antonio; Tsujikawa, Shinji

    2010-12-01

    We study the cosmology of a covariant Galileon field ϕ with five covariant Lagrangians and confront this theory with the most recent cosmological probes: the type Ia supernovae data (Constitution and Union2 sets), cosmic microwave background (WMAP7), and the baryon acoustic oscillations (SDSS7). In the Galileon cosmology with a late-time de Sitter attractor, there is a tracker that attracts solutions with different initial conditions to a common trajectory. Including the cosmic curvature K, we place observational constraints on two distinct cases: (i) the tracker, and (ii) the generic solutions to the equations of motion. We find that the tracker solution can be consistent with the individual observational data, but it is disfavored by the combined data analysis. The generic solutions fare quite well when a nonzero curvature parameter ΩK(0) is taken into account, but the Akaike and Bayesian information criteria show that they are not particularly favored over the ΛCDM model.

  7. LA-(HR-)ICPMS study of serpentinites from ODP Site 920 (23°N MAR): insights on transfers and trace element distribution during serpentinization

    NASA Astrophysics Data System (ADS)

    Andreani, M.; Godard, M.; Mevel, C.

    2009-04-01

    The numerous ultramafic-hosted hydrothermal systems discovered during the last ten years emphasized the importance of mantle peridotite alteration as means of chemical exchange between the mantle and the ocean at slow- and ultra-slow spreading ridges. Yet, little is known on the chemical variability of serpentinites at the ridge and the local scale. This is determinant for constraining mass transfers at ridge axis and then the input budget in subduction zones. We present the results of the detailed petrostructural and geochemical study of serpentinized harzburgites (60-100 % alteration) sampled at ODP Site 920 (23°N, Mid-Atlantic Ridge). A previous detailed microstructural and major element study of pseudomorphic textures and veins of site 920 serpentinites has indicated two main stages of serpentinization which accompany the progressive unroofing of mantle rocks. These stages are distinguished by their mode of mass transfer: a first diffusion-dominated stage occurring below 2 km in depth at 150°

  8. Fixed Costs and Hours Constraints

    ERIC Educational Resources Information Center

    Johnson, William R.

    2011-01-01

    Hours constraints are typically identified by worker responses to questions asking whether they would prefer a job with more hours and more pay or fewer hours and less pay. Because jobs with different hours but the same rate of pay may be infeasible when there are fixed costs of employment or mandatory overtime premia, the constraint in those…

  9. Market segmentation using perceived constraints

    Treesearch

    Jinhee Jun; Gerard Kyle; Andrew Mowen

    2008-01-01

    We examined the practical utility of segmenting potential visitors to Cleveland Metroparks using their constraint profiles. Our analysis identified three segments based on their scores on the dimensions of constraints: Other priorities--visitors who scored the highest on 'other priorities' dimension; Highly Constrained--visitors who scored relatively high on...

  10. On Constraints in Assembly Planning

    SciTech Connect

    Calton, T.L.; Jones, R.E.; Wilson, R.H.

    1998-12-17

    Constraints on assembly plans vary depending on product, assembly facility, assembly volume, and many other factors. Assembly costs and other measures to optimize vary just as widely. To be effective, computer-aided assembly planning systems must allow users to express the plan selection criteria that appIy to their products and production environments. We begin this article by surveying the types of user criteria, both constraints and quality measures, that have been accepted by assembly planning systems to date. The survey is organized along several dimensions, including strategic vs. tactical criteria; manufacturing requirements VS. requirements of the automated planning process itself and the information needed to assess compliance with each criterion. The latter strongly influences the efficiency of planning. We then focus on constraints. We describe a framework to support a wide variety of user constraints for intuitive and efficient assembly planning. Our framework expresses all constraints on a sequencing level, specifying orders and conditions on part mating operations in a number of ways. Constraints are implemented as simple procedures that either accept or reject assembly operations proposed by the planner. For efficiency, some constraints are supplemented with special-purpose modifications to the planner's algorithms. Fast replanning enables an interactive plan-view-constrain-replan cycle that aids in constraint discovery and documentation. We describe an implementation of the framework in a computer-aided assembly planning system and experiments applying the system to a number of complex assemblies, including one with 472 parts.

  11. Fixed Costs and Hours Constraints

    ERIC Educational Resources Information Center

    Johnson, William R.

    2011-01-01

    Hours constraints are typically identified by worker responses to questions asking whether they would prefer a job with more hours and more pay or fewer hours and less pay. Because jobs with different hours but the same rate of pay may be infeasible when there are fixed costs of employment or mandatory overtime premia, the constraint in those…

  12. Credit Constraints for Higher Education

    ERIC Educational Resources Information Center

    Solis, Alex

    2012-01-01

    This paper exploits a natural experiment that produces exogenous variation on credit access to determine the effect on college enrollment. The paper assess how important are credit constraints to explain the gap in college enrollment by family income, and what would be the gap if credit constraints are eliminated. Progress in college and dropout…

  13. Affordances and Constraints in Social Studies Curriculum-Making: The Case of "Jewish Social Studies" in the Early 20th Century

    ERIC Educational Resources Information Center

    Jacobs, Benjamin M.

    2009-01-01

    This document-based historical study explores the nature of the Jewish social studies curriculum in American Jewish schools in the early 20th century (c.1910-1940), a period of significant growth and reform in the modern American Jewish education enterprise. "Jewish social studies" refers to school programs in which Jewish history, Jewish…

  14. Perceived constraints to art museum attendance

    Treesearch

    Jinhee Jun; Gerard Kyle; Joseph T. O' Leary

    2007-01-01

    We explored selected socio-demographic factors that influence the perception of constraints to art museum attendance among a sample of interested individuals who were currently not enjoying art museum visitation. Data from the Survey of Public Participation in the Arts (SPPA), a nationwide survey were used for this study. Using multivariate analysis of variance, we...

  15. Constraints on Children's Judgments of Magical Causality

    ERIC Educational Resources Information Center

    Woolley, Jacqueline D.; Browne, Cheryl A.; Boerger, Elizabeth A.

    2006-01-01

    In 3 studies we addressed the operation of constraints on children's causal judgments. Our primary focus was whether children's beliefs about magical causality, specifically wishing, are constrained by features that govern the attribution of ordinary causality. In Experiment 1, children witnessed situations in which a confederate's wish appeared…

  16. An examination of constraints to wilderness visitation

    Treesearch

    Gary T. Green; J. Michael Bowker; Cassandra Y. Johnson; H. Ken Cordell; Xiongfei Wang

    2007-01-01

    Certain social groups appear notably less in wilderness visitation surveys than their population proportion. This study examines whether different social groups in American society (minorities, women, rural dwellers, low income and less educated populations) perceive more constraints to wilderness visitation than other groups. Logistic regressions were fit to data from...

  17. Constraints on Children's Judgments of Magical Causality

    ERIC Educational Resources Information Center

    Woolley, Jacqueline D.; Browne, Cheryl A.; Boerger, Elizabeth A.

    2006-01-01

    In 3 studies we addressed the operation of constraints on children's causal judgments. Our primary focus was whether children's beliefs about magical causality, specifically wishing, are constrained by features that govern the attribution of ordinary causality. In Experiment 1, children witnessed situations in which a confederate's wish appeared…

  18. Coverage-based constraints for IMRT optimization

    NASA Astrophysics Data System (ADS)

    Mescher, H.; Ulrich, S.; Bangert, M.

    2017-09-01

    Radiation therapy treatment planning requires an incorporation of uncertainties in order to guarantee an adequate irradiation of the tumor volumes. In current clinical practice, uncertainties are accounted for implicitly with an expansion of the target volume according to generic margin recipes. Alternatively, it is possible to account for uncertainties by explicit minimization of objectives that describe worst-case treatment scenarios, the expectation value of the treatment or the coverage probability of the target volumes during treatment planning. In this note we show that approaches relying on objectives to induce a specific coverage of the clinical target volumes are inevitably sensitive to variation of the relative weighting of the objectives. To address this issue, we introduce coverage-based constraints for intensity-modulated radiation therapy (IMRT) treatment planning. Our implementation follows the concept of coverage-optimized planning that considers explicit error scenarios to calculate and optimize patient-specific probabilities q(\\hat{d}, \\hat{v}) of covering a specific target volume fraction \\hat{v} with a certain dose \\hat{d} . Using a constraint-based reformulation of coverage-based objectives we eliminate the trade-off between coverage and competing objectives during treatment planning. In-depth convergence tests including 324 treatment plan optimizations demonstrate the reliability of coverage-based constraints for varying levels of probability, dose and volume. General clinical applicability of coverage-based constraints is demonstrated for two cases. A sensitivity analysis regarding penalty variations within this planing study based on IMRT treatment planning using (1) coverage-based constraints, (2) coverage-based objectives, (3) probabilistic optimization, (4) robust optimization and (5) conventional margins illustrates the potential benefit of coverage-based constraints that do not require tedious adjustment of target volume objectives.

  19. A Hybrid Constraint Representation and Reasoning Framework

    NASA Technical Reports Server (NTRS)

    Golden, Keith; Pang, Wan-Lin

    2003-01-01

    This paper introduces JNET, a novel constraint representation and reasoning framework that supports procedural constraints and constraint attachments, providing a flexible way of integrating the constraint reasoner with a run- time software environment. Attachments in JNET are constraints over arbitrary Java objects, which are defined using Java code, at runtime, with no changes to the JNET source code.

  20. Can Protracted Tectonic Constraints Associated to a Slow Cooling Rate Prevail for 35 My ? The Study Case of the Quartzo Syenite of Ibituruna (SE-Brazil)

    NASA Astrophysics Data System (ADS)

    Vauchez, A.; Petitgirard, S.; Egydia-Silva, M.; Bruguier, O.; Camps, P.; Monie, P.; Babinski, M.; Mondou, M.

    2008-12-01

    could be explained by a very slow cooling rate on the whole area or a protracted deformation, or more probably, a mixing of the two phenomena. A few clues indicate a low cooling rate such as: i) equilibrated microstructure in the syenite (triple junction) ii) thermal overgrowths on zircons iii) post- kinematic grain growth of quartz in the mylonites. Using 40Ar-39Ar ages extracted from minerals of the different units, we are able to deduce the primary stages of the thermal history which clearly describe a low cooling rate, with 3 degrees C per My between 570 and 500 My, and 5 degrees C per My between 500 and 460 My. While combining AMS, field and thin rock sections observations with isotopic dating and thermochronolgy, it is still difficult to decipher on the mystery of the Ibituruna syenite emplacement. However, through this study we demonstrate the necessity to use and cross as much as possible techniques in order to clear up hidden zones. Such results might be characteristic to particulars regimes associated to hot orogens with HT-LP conditions with a slow cooling rate and protracted tectonic constraints or multiple deformation stage at High Temperature.

  1. Infrared Kuiper Belt Constraints

    SciTech Connect

    Teplitz, V.L.; Stern, S.A.; Anderson, J.D.; Rosenbaum, D.; Scalise, R.J.; Wentzler, P.

    1999-05-01

    We compute the temperature and IR signal of particles of radius {ital a} and albedo {alpha} at heliocentric distance {ital R}, taking into account the emissivity effect, and give an interpolating formula for the result. We compare with analyses of {ital COBE} DIRBE data by others (including recent detection of the cosmic IR background) for various values of heliocentric distance {ital R}, particle radius {ital a}, and particle albedo {alpha}. We then apply these results to a recently developed picture of the Kuiper belt as a two-sector disk with a nearby, low-density sector (40{lt}R{lt}50{endash}90 AU) and a more distant sector with a higher density. We consider the case in which passage through a molecular cloud essentially cleans the solar system of dust. We apply a simple model of dust production by comet collisions and removal by the Poynting-Robertson effect to find limits on total and dust masses in the near and far sectors as a function of time since such a passage. Finally, we compare Kuiper belt IR spectra for various parameter values. Results of this work include: (1) numerical limits on Kuiper belt dust as a function of ({ital R}, {ital a}, {alpha}) on the basis of four alternative sets of constraints, including those following from recent discovery of the cosmic IR background by Hauser et al.; (2) application to the two-sector Kuiper belt model, finding mass limits and spectrum shape for different values of relevant parameters including dependence on time elapsed since last passage through a molecular cloud cleared the outer solar system of dust; and (3) potential use of spectral information to determine time since last passage of the Sun through a giant molecular cloud. {copyright} {ital {copyright} 1999.} {ital The American Astronomical Society}

  2. Evolutionary constraints or opportunities?

    PubMed Central

    Sharov, Alexei A.

    2014-01-01

    Natural selection is traditionally viewed as a leading factor of evolution, whereas variation is assumed to be random and non-directional. Any order in variation is attributed to epigenetic or developmental constraints that can hinder the action of natural selection. In contrast I consider the positive role of epigenetic mechanisms in evolution because they provide organisms with opportunities for rapid adaptive change. Because the term “constraint” has negative connotations, I use the term “regulated variation” to emphasize the adaptive nature of phenotypic variation, which helps populations and species to survive and evolve in changing environments. The capacity to produce regulated variation is a phenotypic property, which is not described in the genome. Instead, the genome acts as a switchboard, where mostly random mutations switch “on” or “off” preexisting functional capacities of organism components. Thus, there are two channels of heredity: informational (genomic) and structure-functional (phenotypic). Functional capacities of organisms most likely emerged in a chain of modifications and combinations of more simple ancestral functions. The role of DNA has been to keep records of these changes (without describing the result) so that they can be reproduced in the following generations. Evolutionary opportunities include adjustments of individual functions, multitasking, connection between various components of an organism, and interaction between organisms. The adaptive nature of regulated variation can be explained by the differential success of lineages in macro-evolution. Lineages with more advantageous patterns of regulated variation are likely to produce more species and secure more resources (i.e., long-term lineage selection). PMID:24769155

  3. Constraints on Teachers' Classroom Effectiveness: The Teachers' Perspective. Policy Bulletin.

    ERIC Educational Resources Information Center

    Buechler, Mark

    This bulletin summarizes the findings of a study that sought to determine what policies, regulations, and practices teachers believed posed the most significant constraints on their classroom activities; whether these constraints originated at the federal, state, local, or school level; and what effect the costraints had on quality instruction and…

  4. Balancing Flexible Constraints and Measurement Precision in Computerized Adaptive Testing

    ERIC Educational Resources Information Center

    Moyer, Eric L.; Galindo, Jennifer L.; Dodd, Barbara G.

    2012-01-01

    Managing test specifications--both multiple nonstatistical constraints and flexibly defined constraints--has become an important part of designing item selection procedures for computerized adaptive tests (CATs) in achievement testing. This study compared the effectiveness of three procedures: constrained CAT, flexible modified constrained CAT,…

  5. Credit Constraints in Education. NBER Working Paper No. 17435

    ERIC Educational Resources Information Center

    Lochner, Lance; Monge-Naranjo, Alexander

    2011-01-01

    We review studies of the impact of credit constraints on the accumulation of human capital. Evidence suggests that credit constraints are increasingly important for schooling and other aspects of households' behavior. We highlight the importance of early childhood investments, since their response largely determines the impact of credit…

  6. Balancing Flexible Constraints and Measurement Precision in Computerized Adaptive Testing

    ERIC Educational Resources Information Center

    Moyer, Eric L.; Galindo, Jennifer L.; Dodd, Barbara G.

    2012-01-01

    Managing test specifications--both multiple nonstatistical constraints and flexibly defined constraints--has become an important part of designing item selection procedures for computerized adaptive tests (CATs) in achievement testing. This study compared the effectiveness of three procedures: constrained CAT, flexible modified constrained CAT,…

  7. Credit Constraints in Education. NBER Working Paper No. 17435

    ERIC Educational Resources Information Center

    Lochner, Lance; Monge-Naranjo, Alexander

    2011-01-01

    We review studies of the impact of credit constraints on the accumulation of human capital. Evidence suggests that credit constraints are increasingly important for schooling and other aspects of households' behavior. We highlight the importance of early childhood investments, since their response largely determines the impact of credit…

  8. Individuals' interpretation of constraints: a new perspective on existing theory

    Treesearch

    Po-Ju Chen; Deborah Kerstetter; Linda Caldwell

    2001-01-01

    The travel decision-making process is influenced by a number of factors. One of the most important yet infrequently studied factors is "perceived constraints." Nearly a decade ago Crawford, Jackson and Godbey (1991) developed a framework to guide constraints research. Numerous authors have utilized this framework but results have suggested that individuals...

  9. Combined garnet and zircon geochronology and trace elements studies - constraints of the UHP-(U)HT evolution of Orlica-Śnieżnik Dome (NE Bohemian Massif).

    NASA Astrophysics Data System (ADS)

    Walczak, Katarzyna; Anczkiewicz, Robert; Szczepański, Jacek; Rubatto, Daniela

    2017-04-01

    The Orlica-Śnieżnik Dome (OSD), located on the NE margin of the Bohemian Massif, is predominantly composed of amphibolite-facies orthogneiss that contain bodies of HP and UHP eclogites and granulites. Numerous geochronological studies have been undertaken to constrain the timing of the ultra-high grade metamorphic event. Despite this, the exact timing of UHP-(U)HT conditions remain dubious (e.g. Brueckner et al., 1991; Anczkiewicz et al., 2007; Bröcker et al., 2009 & 2010). We have utilized garnet and zircon geochronology to provide time constraints on the evolution of the UHT-(U)HP rocks of the OSD. We have combined the ages with trace element analyses in garnet and zircon to better understand the significance of the obtained ages in petrological context. Lu-Hf grt-wr dating of peritectic garnet from two felsic granulites constrained the time of its initial growth at 346.9 ± 1.2 and 348.3 ± 2.0 Ma, recording peak conditions of 2.7 GPa and 950°C (e.g. Ferrero et al., 2015). In situ U-Pb SHRIMP dating of zircon from the same granulite gave a younger age of 342.2 ± 3.4 Ma. HREE partitioning between garnet rim and metamorphic zircon indicate their growth in equilibrium, hence, the U-Pb zircon date constrains the terminal phase of garnet crystallization. Similar ages were obtained from two eclogite bodies from Międzygórze and Nowa Wieś localities; Lu-Hf (grt-cpx-wr) dating provided ages of 346.5 ± 2.4 and 348.1 ± 9.1 Ma for samples from Międzygórze and Nowa Wieś, respectively. The same age (within error) of 346.3 ± 5.2 Ma was reported by Bröcker et al. (2010) for zircon from the Międzygórze eclogite. Comparison of REE concentrations in garnet (this study) and in metamorphic zircon (reported in Bröcker et al., 2010) indicate that garnet and zircon crystallized in equilibrium. Furthermore, M-HREE patterns observed in both garnet and zircon strongly suggest their growth at eclogite facies conditions. Sm-Nd garnet ages obtained for both felsic and mafic

  10. Resource allocation using constraint propagation

    NASA Technical Reports Server (NTRS)

    Rogers, John S.

    1990-01-01

    The concept of constraint propagation was discussed. Performance increases are possible with careful application of these constraint mechanisms. The degree of performance increase is related to the interdependence of the different activities resource usage. Although this method of applying constraints to activities and resources is often beneficial, it is obvious that this is no panacea cure for the computational woes that are experienced by dynamic resource allocation and scheduling problems. A combined effort for execution optimization in all areas of the system during development and the selection of the appropriate development environment is still the best method of producing an efficient system.

  11. Understanding the leisure constraints of Hispanic-Americans in Northern Virginia: an exploratory analysis of constraints, socioeconomic status and acculturation

    Treesearch

    Edward F, II Byrne; Ellen B. Drogin Rodgers

    2003-01-01

    The purpose of this study is to investigate the constraints to use of outdoor recreation resources and participation in leisure activities among Hispanic restaurant workers in Northern Virginia; specifically, the relationship of socioeconomic status and acculturation to leisure constraints. The dramatic rate of increase of Hispanic-Americans, the group's low...

  12. Recent Hydrothermal Fluid Chemistry from EPR 13°N: Phase Equilibria Constraints with Applicability to the Integrated Study of Basalt-Hosted Hydrothermal Systems

    NASA Astrophysics Data System (ADS)

    Pester, N. J.; Ding, K.; Seyfried, W. E.

    2009-12-01

    -phase boundary and, therefore, a maximum reaction temperature of ~450°C can be inferred if we assume phase separation occurred at a maximum depth of 1.5 km below seafloor. Temperatures derived from the Fe/Mn geothermometer are in good agreement with model Fe, H2, and H2S values based on the buffered mineral assemblage; Pyrite-Magnetite-Anhydrite-An70-Chlorite-Tremolite-Quartz, especially above 375°C. Dorian and Grand Bonum have dissolved Si values of 16.5 and 14.6 mmol/kg, respectively. Assuming these fluids to be quartz saturated, the pressure and temperature sensitivity of dissolved Si allows an isobaric temperature increase of as little as 10°C to account for the lower Si values from Grand Bonum. This temperature deviation is well within the temperature difference proposed by the Fe/Mn geothermometer. This effectively demonstrates that the Fe/Mn geothermometer provides valuable constraints when interpreting reaction conditions based on dissolved Si for all basalt-hosted hydrothermal systems. In addition, this relationship will be useful for demonstrating time series changes in subseafloor reaction temperatures at Integrated Study Sites such as EPR 9°N, especially in the aftermath of an eruption/magmatic event.

  13. Fidelity of the protein structure reconstruction from inter-residue proximity constraints.

    PubMed

    Chen, Yiwen; Ding, Feng; Dokholyan, Nikolay V

    2007-06-28

    Inter-residue proximity constraints obtained in such experiments as cross-linking/mass spectrometry are important sources of information for protein structure determination. A central question in structure determination using these constraints is, What is the minimal number of inter-residue constraints needed to determine the fold of a protein? It is also unknown how the different structural aspects of constraints differentiate their ability in determining the native fold and whether there is a rational strategy for selecting constraints that feature higher fidelity in structure determination. To shed light on these questions, we study the fidelity of protein fold determination using theoretical inter-residue proximity constraints derived from protein native structures and the effect of various subsets of such constraints on fold determination. We show that approximately 70% randomly selected constraints are sufficient for determining the fold of a domain (with an average root-mean-square deviation of constraint selection often outperforms the rational strategy that predominantly favors the constraints representing global structural features. To uncover a strategy for constraint selection for the optimal structure determination, we study the role of the topological properties of these constraints. Interestingly, we do not observe any correlation between various simple topological properties of the selected constraints, emphasizing different global and local structural features, and the performance of these constraints, suggesting that accurate protein structure determination relies on a composite of global and local structural information.

  14. Constraint-based stereo matching

    NASA Technical Reports Server (NTRS)

    Kuan, D. T.

    1987-01-01

    The major difficulty in stereo vision is the correspondence problem that requires matching features in two stereo images. Researchers describe a constraint-based stereo matching technique using local geometric constraints among edge segments to limit the search space and to resolve matching ambiguity. Edge segments are used as image features for stereo matching. Epipolar constraint and individual edge properties are used to determine possible initial matches between edge segments in a stereo image pair. Local edge geometric attributes such as continuity, junction structure, and edge neighborhood relations are used as constraints to guide the stereo matching process. The result is a locally consistent set of edge segment correspondences between stereo images. These locally consistent matches are used to generate higher-level hypotheses on extended edge segments and junctions to form more global contexts to achieve global consistency.

  15. Geochemical constraints on Earth's core composition

    NASA Astrophysics Data System (ADS)

    Siebert, Julien

    2016-04-01

    The density of the core as measured from seismic-wave velocities is lower (by 10-15%) than that of pure iron, and therefore the core must also contain some light elements. Geophysical and cosmochemical constraints indicate that obvious candidates for these light elements include silicon, oxygen, and sulfur. These elements have been studied extensively for the past 30 years but a joint solution fulfilling all the requirements imposed by cosmochemistry and geochemistry, seismology, and models of Earth's accretion and core formation is still a highly controversial subject. Here are presented new experimental data in geochemistry used to place constraints on Earth's core composition. Metal-silicate partitioning experiments were performed at pressures and temperatures directly similar to those that prevailed in a deep magma ocean in the early Earth. The results show that core formation can reconcile the observed concentrations of siderophile elements in the silicate mantle with geophysical constraints on light elements in the core. Partitioning results also lead to a core containing less than 1 wt.% of sulfur, inconsistent with a S-rich layer to account for the observed structure of the outer core. Additionally, isotopic fractionations in core formation experiments are presented. This experimental tool merging the fields of experimental petrology and isotope geochemistry represents a promising approach, providing new independent constraints on the nature of light elements in the core.

  16. Thermodynamic constraints for biochemical networks.

    PubMed

    Beard, Daniel A; Babson, Eric; Curtis, Edward; Qian, Hong

    2004-06-07

    The constraint-based approach to analysis of biochemical systems has emerged as a useful tool for rational metabolic engineering. Flux balance analysis (FBA) is based on the constraint of mass conservation; energy balance analysis (EBA) is based on non-equilibrium thermodynamics. The power of these approaches lies in the fact that the constraints are based on physical laws, and do not make use of unknown parameters. Here, we show that the network structure (i.e. the stoichiometric matrix) alone provides a system of constraints on the fluxes in a biochemical network which are feasible according to both mass balance and the laws of thermodynamics. A realistic example shows that these constraints can be sufficient for deriving unambiguous, biologically meaningful results. The thermodynamic constraints are obtained by comparing of the sign pattern of the flux vector to the sign patterns of the cycles of the internal cycle space via connection between stoichiometric network theory (SNT) and the mathematical theory of oriented matroids.

  17. Foundations of support constraint machines.

    PubMed

    Gnecco, Giorgio; Gori, Marco; Melacci, Stefano; Sanguineti, Marcello

    2015-02-01

    The mathematical foundations of a new theory for the design of intelligent agents are presented. The proposed learning paradigm is centered around the concept of constraint, representing the interactions with the environment, and the parsimony principle. The classical regularization framework of kernel machines is naturally extended to the case in which the agents interact with a richer environment, where abstract granules of knowledge, compactly described by different linguistic formalisms, can be translated into the unified notion of constraint for defining the hypothesis set. Constrained variational calculus is exploited to derive general representation theorems that provide a description of the optimal body of the agent (i.e., the functional structure of the optimal solution to the learning problem), which is the basis for devising new learning algorithms. We show that regardless of the kind of constraints, the optimal body of the agent is a support constraint machine (SCM) based on representer theorems that extend classical results for kernel machines and provide new representations. In a sense, the expressiveness of constraints yields a semantic-based regularization theory, which strongly restricts the hypothesis set of classical regularization. Some guidelines to unify continuous and discrete computational mechanisms are given so as to accommodate in the same framework various kinds of stimuli, for example, supervised examples and logic predicates. The proposed view of learning from constraints incorporates classical learning from examples and extends naturally to the case in which the examples are subsets of the input space, which is related to learning propositional logic clauses.

  18. Optimal Stopping with Information Constraint

    SciTech Connect

    Lempa, Jukka

    2012-10-15

    We study the optimal stopping problem proposed by Dupuis and Wang (Adv. Appl. Probab. 34:141-157, 2002). In this maximization problem of the expected present value of the exercise payoff, the underlying dynamics follow a linear diffusion. The decision maker is not allowed to stop at any time she chooses but rather on the jump times of an independent Poisson process. Dupuis and Wang (Adv. Appl. Probab. 34:141-157, 2002), solve this problem in the case where the underlying is a geometric Brownian motion and the payoff function is of American call option type. In the current study, we propose a mild set of conditions (covering the setup of Dupuis and Wang in Adv. Appl. Probab. 34:141-157, 2002) on both the underlying and the payoff and build and use a Markovian apparatus based on the Bellman principle of optimality to solve the problem under these conditions. We also discuss the interpretation of this model as optimal timing of an irreversible investment decision under an exogenous information constraint.

  19. Efficacy and acceptability of reduced intensity constraint-induced movement therapy for children aged 9-11 years with hemiplegic cerebral palsy: a pilot study.

    PubMed

    McConnell, Karen; Johnston, Linda; Kerr, Claire

    2014-08-01

    Assess efficacy and acceptability of reduced intensity constraint-induced movement therapy (CIMT) in children with cerebral palsy (CP). Single-subject research design and semi-structured interviews. Children (9-11y) with hemiplegia underwent five baseline assessments followed by two weeks CIMT. Six further assessments were performed during treatment and follow-up phases. The primary outcome was the Melbourne Assessment of Unilateral Upper Limb Function (MUUL). Quantitative data were analysed using standard single-subject methods and qualitative data by thematic analysis. Four of the seven participants demonstrated statistically significant improvements in MUUL (3-11%, p < .05). Two participants achieved significant improvements in active range of motion but strength and tone remained largely unchanged. Qualitative interviews highlighted limitations of the restraint, importance of family involvement, and coordination of treatment with education. Reduced intensity CIMT may be effective for some children in this population; however it is not suitable for all children with hemiplegia.

  20. Synergistic effect of combined transcranial direct current stimulation/constraint-induced movement therapy in children and young adults with hemiparesis: study protocol.

    PubMed

    Gillick, Bernadette; Menk, Jeremiah; Mueller, Bryon; Meekins, Gregg; Krach, Linda E; Feyma, Timothy; Rudser, Kyle

    2015-11-12

    Perinatal stroke occurs in more than 1 in 2,500 live births and resultant congenital hemiparesis necessitates investigation into interventions which may improve long-term function and decreased burden of care beyond current therapies ( http://www.cdc.gov/ncbddd/cp/data.html ). Constraint-Induced Movement Therapy (CIMT) is recognized as an effective hemiparesis rehabilitation intervention. Transcranial direct current stimulation as an adjunct treatment to CIMT may potentiate neuroplastic responses and improve motor function. The methodology of a clinical trial in children designed as a placebo-controlled, serial -session, non-invasive brain stimulation trial incorporating CIMT is described here. The primary hypotheses are 1) that no serious adverse events will occur in children receiving non-invasive brain stimulation and 2) that children in the stimulation intervention group will show significant improvements in hand motor function compared to children in the placebo stimulation control group. A randomized, controlled, double-blinded clinical trial. Twenty children and/or young adults (ages 8-21) with congenital hemiparesis, will be enrolled. The intervention group will receive ten 2-hour sessions of transcranial direct current stimulation combined with constraint-induced movement therapy and the control group will receive sham stimulation with CIMT. The primary outcome measure is safety assessment of transcranial direct current stimulation by physician evaluation, vital sign monitoring and symptom reports. Additionally, hand function will be evaluated using the Assisting Hand Assessment, grip strength and assessment of goals using the Canadian Occupational Performance Measure. Neuroimaging will confirm diagnoses, corticospinal tract integrity and cortical activation. Motor cortical excitability will also be examined using transcranial magnetic stimulation techniques. Combining non-invasive brain stimulation and CIMT interventions has the potential to improve motor

  1. Revisiting Studies of the Statistical Property of a Strong Gravitational Lens System and Model-Independent Constraint on the Curvature of the Universe

    NASA Astrophysics Data System (ADS)

    Xia, Jun-Qing; Yu, Hai; Wang, Guo-Jian; Tian, Shu-Xun; Li, Zheng-Xiang; Cao, Shuo; Zhu, Zong-Hong

    2017-01-01

    In this paper, we use a recently compiled data set, which comprises 118 galactic-scale strong gravitational lensing (SGL) systems to constrain the statistical property of the SGL system as well as the curvature of the universe without assuming any fiducial cosmological model. Based on the singular isothermal ellipsoid (SIE) model of the SGL system, we obtain that the constrained curvature parameter {{{Ω }}}{{k}} is close to zero from the SGL data, which is consistent with the latest result of Planck measurement. More interestingly, we find that the parameter f in the SIE model is strongly correlated with the curvature {{{Ω }}}{{k}}. Neglecting this correlation in the analysis will significantly overestimate the constraining power of SGL data on the curvature. Furthermore, the obtained constraint on f is different from previous results: f=1.105+/- 0.030 (68% confidence level [C.L.]), which means that the standard singular isothermal sphere (SIS) model (f = 1) is disfavored by the current SGL data at more than a 3σ C.L. We also divide all of the SGL data into two parts according to the centric stellar velocity dispersion {σ }{{c}} and find that the larger the value of {σ }{{c}} for the subsample, the more favored the standard SIS model is. Finally, we extend the SIE model by assuming the power-law density profiles for the total mass density, ρ ={ρ }0{(r/{r}0)}-α , and luminosity density, ν ={ν }0{(r/{r}0)}-δ , and obtain the constraints on the power-law indices: α =1.95+/- 0.04 and δ =2.40+/- 0.13 at a 68% C.L. When assuming the power-law index α =δ =γ , this scenario is totally disfavored by the current SGL data, {χ }\\min ,γ 2-{χ }\\min ,{SIE}2≃ 53.

  2. The Effects of Two Levels of Linguistic Constraint on Echolalia and Generative Language Production in Children with Autism.

    ERIC Educational Resources Information Center

    Rydell, Patrick J.; Mirenda, Pat

    1991-01-01

    This study of 3 boys (ages 5-6) with autism found that adult high-constraint antecedent utterances elicited more verbal utterances in general, including subjects' echolalia; adult low-constraint utterances elicited more subject high-constraint utterances; and the degree of adult-utterance constraint did not influence the mean lengths of subjects'…

  3. Perceptual constraints in phonotactic learning.

    PubMed

    Endress, Ansgar D; Mehler, Jacques

    2010-02-01

    Structural regularities in language have often been attributed to symbolic or statistical general purpose computations, whereas perceptual factors influencing such generalizations have received less interest. Here, we use phonotactic-like constraints as a case study to ask whether the structural properties of specific perceptual and memory mechanisms may facilitate the acquisition of grammatical-like regularities. Participants learned that the consonants C and C had to come from distinct sets in words of the form CVccVC (where the critical consonants were in word edges) but not in words of the form cVCCVc (where the critical consonants were in word middles). Control conditions ruled out attentional or psychophysical difficulties in word middles. Participants did, however, learn such regularities in word middles when natural consonant classes were used instead of arbitrary consonant sets. We conclude that positional generalizations may be learned preferentially using edge-based positional codes, but that participants can also use other mechanisms when other linguistic cues are given.

  4. Percolation of spatially constraint networks

    NASA Astrophysics Data System (ADS)

    Li, Daqing; Li, Guanliang; Kosmidis, Kosmas; Stanley, H. E.; Bunde, Armin; Havlin, Shlomo

    2011-03-01

    We study how spatial constraints are reflected in the percolation properties of networks embedded in one-dimensional chains and two-dimensional lattices. We assume long-range connections between sites on the lattice where two sites at distance r are chosen to be linked with probability p(r)~r-δ. Similar distributions have been found in spatially embedded real networks such as social and airline networks. We find that for networks embedded in two dimensions, with 2<δ<4, the percolation properties show new intermediate behavior different from mean field, with critical exponents that depend on δ. For δ<2, the percolation transition belongs to the universality class of percolation in Erdös-Rényi networks (mean field), while for δ>4 it belongs to the universality class of percolation in regular lattices. For networks embedded in one dimension, we find that, for δ<1, the percolation transition is mean field. For 1<δ<2, the critical exponents depend on δ, while for δ>2 there is no percolation transition as in regular linear chains.

  5. Developmental constraints on behavioural flexibility

    PubMed Central

    Holekamp, Kay E.; Swanson, Eli M.; Van Meter, Page E.

    2013-01-01

    We suggest that variation in mammalian behavioural flexibility not accounted for by current socioecological models may be explained in part by developmental constraints. From our own work, we provide examples of constraints affecting variation in behavioural flexibility, not only among individuals, but also among species and higher taxonomic units. We first implicate organizational maternal effects of androgens in shaping individual differences in aggressive behaviour emitted by female spotted hyaenas throughout the lifespan. We then compare carnivores and primates with respect to their locomotor and craniofacial adaptations. We inquire whether antagonistic selection pressures on the skull might impose differential functional constraints on evolvability of skulls and brains in these two orders, thus ultimately affecting behavioural flexibility in each group. We suggest that, even when carnivores and primates would theoretically benefit from the same adaptations with respect to behavioural flexibility, carnivores may nevertheless exhibit less behavioural flexibility than primates because of constraints imposed by past adaptations in the morphology of the limbs and skull. Phylogenetic analysis consistent with this idea suggests greater evolutionary lability in relative brain size within families of primates than carnivores. Thus, consideration of developmental constraints may help elucidate variation in mammalian behavioural flexibility. PMID:23569298

  6. Developmental constraints on behavioural flexibility.

    PubMed

    Holekamp, Kay E; Swanson, Eli M; Van Meter, Page E

    2013-05-19

    We suggest that variation in mammalian behavioural flexibility not accounted for by current socioecological models may be explained in part by developmental constraints. From our own work, we provide examples of constraints affecting variation in behavioural flexibility, not only among individuals, but also among species and higher taxonomic units. We first implicate organizational maternal effects of androgens in shaping individual differences in aggressive behaviour emitted by female spotted hyaenas throughout the lifespan. We then compare carnivores and primates with respect to their locomotor and craniofacial adaptations. We inquire whether antagonistic selection pressures on the skull might impose differential functional constraints on evolvability of skulls and brains in these two orders, thus ultimately affecting behavioural flexibility in each group. We suggest that, even when carnivores and primates would theoretically benefit from the same adaptations with respect to behavioural flexibility, carnivores may nevertheless exhibit less behavioural flexibility than primates because of constraints imposed by past adaptations in the morphology of the limbs and skull. Phylogenetic analysis consistent with this idea suggests greater evolutionary lability in relative brain size within families of primates than carnivores. Thus, consideration of developmental constraints may help elucidate variation in mammalian behavioural flexibility.

  7. Atom-Interferometry Constraints on Dark Energy

    NASA Astrophysics Data System (ADS)

    Mueller, Holger

    2016-03-01

    If dark energy is a light scalar field, it might interact with normal matter. The interactions, however, are suppressed in some leading models, which are thus compatible with current cosmological observations as well as solar-system and laboratory studies. Such suppression typically relies on the scalar's interaction with macroscopic amounts of ordinary matter, but can be bypassed by studying the interaction with individual particles. Using an atom interferometer, we have placed tight constraints on so-called chameleon models, ruling out interaction parameters βM > 4 ×104 . This limit is improved by 2.5 orders of magnitude relative to previous experiments. We have already increased the sensitivity of our interferometer hundredfold and are expecting a new constraint soon. Purpose-built experiments in the lab or on the international space station will completely close the gap and rule out out chameleons and other theories, such as axions, dark photons, symmetrons or f (R) gravity.

  8. Hydrogeologic Constraints on Yucatan's Development.

    PubMed

    Doehring, D O; Butler, J H

    1974-11-15

    The Republic of Mexico has an ambitious and effective national water program. The Secretaria de Recursos Hidraulicos (SRH), whose director has cabinet rank in the federal government, is one of the most professionally distinguished government agencies of its kind in the Americas. Resources for the Future, Inc., has been assisting the World Bank with a water planning study which the Bank is undertaking jointly with the Mexican government. The study is intended to provide guidelines for the development of government policies and projects designed to bring about the most efficient use of Mexico's water resources. However, to date, their study has not been directed toward the growing problems of the northern Yucatáan Peninsula which are discussed here. LeGrand (13) suggested that man has inherited a harsh environment in carbonate terranes. In the case of the northern Yucatán Peninsula, the physical environment creates a set of hydrogeologic constraints to future economic and social development. Planning for intermediate and long-range land use on the peninsula must be related directly to the limited and fragile groundwater source. Continued contamination will make future aquifer management a difficult challenge for federal, state, and territorial agencies. We conclude that any strategy for long-range land use in the study area should include establishment of a regional aquifermonitoring network for long-term measurements of key hydrogeologic parameters, including precipitation, evapotranspiration, water table elevations, and water quality. Information from this network would flow into a central facility for storage, interpretation, and analysis. At present the SRH is collecting some of these data. Expansion of the existing program to provide sound information for regional planning will greatly benefit present as well as future generations. If such a program is implemented, it will represent a model for regional planning in other tropical and subtropical karstic

  9. Constraints on Transportable Ion Beam Power.

    DTIC Science & Technology

    1982-11-12

    17. DISTRIBUTION STATEMENT (of the abstract ent*,od in Block 20, It dlffo-ent from Report) 10. SUPPLEMENTARY NOTES *Present address: JAYCOR, Inc., 205...loss Transport System studyStability, \\ 20. ABSTRACT (Continue or reverse side If neceesry and Identify by block number) . A ’Constraints on...be replaced by a much more complicated expressione because of the more complex chemistry and radiation processes in higher atomic number gases. The

  10. The transmission interface constraint problem

    SciTech Connect

    Baldick, R.; Kahn, E.

    1993-10-01

    Electric power transmission systems exhibit a number of complex constraints on their operation and usage. When a network is subject to a constraint that limits the amount of power that can be moved from one region to another, there is said to be an interface limit. The power systems literature gives no general treatment of the engineering-economics of this ubiquitous phenomenon. Particular aspects of interface limits are typically discussed in sophisticated technical detail, but the general engineering-economic trade-offs involved in relieving interface constraints have not been systematically addressed. We approach this problem in the spirit of a heuristic model. Such models are quite valuable under current industry conditions because they delineate technical opportunities and choices in situations where there may be conflicting views among competing parties and regulatory authorities. We organize and enumerate the choices, clarify the practical conditions that dictate the optimum in particular cases, and help to motivate the final choices made by planners.

  11. Symmetry constraint for foreground extraction.

    PubMed

    Fu, Huazhu; Cao, Xiaochun; Tu, Zhuowen; Lin, Dongdai

    2014-05-01

    Symmetry as an intrinsic shape property is often observed in natural objects. In this paper, we discuss how explicitly taking into account the symmetry constraint can enhance the quality of foreground object extraction. In our method, a symmetry foreground map is used to represent the symmetry structure of the image, which includes the symmetry matching magnitude and the foreground location prior. Then, the symmetry constraint model is built by introducing this symmetry structure into the graph-based segmentation function. Finally, the segmentation result is obtained via graph cuts. Our method encourages objects with symmetric parts to be consistently extracted. Moreover, our symmetry constraint model is applicable to weak symmetric objects under the part-based framework. Quantitative and qualitative experimental results on benchmark datasets demonstrate the advantages of our approach in extracting the foreground. Our method also shows improved results in segmenting objects with weak, complex symmetry properties.

  12. Genetic map construction with constraints

    SciTech Connect

    Clark, D.A.; Rawlings, C.J.; Soursenot, S.

    1994-12-31

    A pilot program, CME, is described for generating a physical genetic map from hybridization fingerprinting data. CME is implemented in the parallel constraint logic programming language ElipSys. The features of constraint logic programming are used to enable the integration of preexisting mapping information (partial probe orders from cytogenetic maps and local physical maps) into the global map generation process, while parallelism enables the search space to be traversed more efficiently. CME was tested using data from chromosome 2 of Schizosaccharomyces pombe and was found able to generate maps as well as (and sometimes better than) a more traditional method. This paper illustrates the practical benefits of using a symbolic logic programming language and shows that the features of constraint handling and parallel execution bring the development of practical systems based on Al programming technologies nearer to being a reality.

  13. Magnetotail dynamics under isobaric constraints

    NASA Technical Reports Server (NTRS)

    Birn, Joachim; Schindler, Karl; Janicke, Lutz; Hesse, Michael

    1994-01-01

    Using linear theory and nonlinear MHD simulations, we investigate the resistive and ideal MHD stability of two-dimensional plasma configurations under the isobaric constraint dP/dt = 0, which in ideal MHD is equivalent to conserving the pressure function P = P(A), where A denotes the magnetic flux. This constraint is satisfied for incompressible modes, such as Alfven waves, and for systems undergoing energy losses. The linear stability analysis leads to a Schroedinger equation, which can be investigated by standard quantum mechanics procedures. We present an application to a typical stretched magnetotail configuration. For a one-dimensional sheet equilibrium characteristic properties of tearing instability are rediscovered. However, the maximum growth rate scales with the 1/7 power of the resistivity, which implies much faster growth than for the standard tearing mode (assuming that the resistivity is small). The same basic eigen-mode is found also for weakly two-dimensional equilibria, even in the ideal MHD limit. In this case the growth rate scales with the 1/4 power of the normal magnetic field. The results of the linear stability analysis are confirmed qualitatively by nonlinear dynamic MHD simulations. These results suggest the interesting possibility that substorm onset, or the thinning in the late growth phase, is caused by the release of a thermodynamic constraint without the (immediate) necessity of releasing the ideal MHD constraint. In the nonlinear regime the resistive and ideal developments differ in that the ideal mode does not lead to neutral line formation without the further release of the ideal MHD constraint; instead a thin current sheet forms. The isobaric constraint is critically discussed. Under perhaps more realistic adiabatic conditions the ideal mode appears to be stable but could be driven by external perturbations and thus generate the thin current sheet in the late growth phase, before a nonideal instability sets in.

  14. Greenstone belt tectonics: Thermal constraints

    NASA Technical Reports Server (NTRS)

    Bickle, M. J.; Nisbet, E. G.

    1986-01-01

    Archaean rocks provide a record of the early stages of planetary evolution. The interpretation is frustrated by the probable unrepresentative nature of the preserved crust and by the well known ambiguities of tectonic geological synthesis. Broad constraints can be placed on the tectonic processes in the early Earth from global scale modeling of thermal and chemical evolution of the Earth and its hydrosphere and atmosphere. The Archean record is the main test of such models. Available general model constraints are outlined based on the global tectonic setting within which Archaean crust evolved and on the direct evidence the Archaean record provides, particularly the thermal state of the early Earth.

  15. Scale-free center-of-mass displacement correlations in polymer melts without topological constraints and momentum conservation: a bond-fluctuation model study.

    PubMed

    Wittmer, J P; Polińska, P; Meyer, H; Farago, J; Johner, A; Baschnagel, J; Cavallo, A

    2011-06-21

    By Monte Carlo simulations of a variant of the bond-fluctuation model without topological constraints, we examine the center-of-mass (COM) dynamics of polymer melts in d = 3 dimensions. Our analysis focuses on the COM displacement correlation function C(N)(t)≈∂(t) (2)h(N)(t)/2, measuring the curvature of the COM mean-square displacement h(N)(t). We demonstrate that C(N)(t) ≈ -(R(N)∕T(N))(2)(ρ∗/ρ) f(x = t/T(N)) with N being the chain length (16 ≤ N ≤ 8192), R(N) ∼ N(1/2) is the typical chain size, T(N) ∼ N(2) is the longest chain relaxation time, ρ is the monomer density, ρ(*)≈N/R(N) (d) is the self-density, and f(x) is a universal function decaying asymptotically as f(x) ∼ x(-ω) with ω = (d + 2) × α, where α = 1/4 for x ≪ 1 and α = 1/2 for x ≫ 1. We argue that the algebraic decay NC(N)(t) ∼ -t(-5/4) for t ≪ T(N) results from an interplay of chain connectivity and melt incompressibility giving rise to the correlated motion of chains and subchains.

  16. Changes in Serial Optical Topography and TMS during Task Performance after Constraint-Induced Movement Therapy in Stroke: A Case Study

    PubMed Central

    Park, Si-Woon; Butler, Andrew J.; Cavalheiro, Vanessa; Alberts, Jay L.; Wolf, Steven L.

    2013-01-01

    The authors examined serial changes in optical topography in a stroke patient performing a functional task, as well as clinical and physiologic measures while undergoing constraint-induced therapy (CIT). A 73-year-old right hemiparetic patient, who had a subcortical stroke 4 months previously, received 2 weeks of CIT. During the therapy, daily optical topography imaging using near-infrared light was measured serially while the participant performed a functional key-turning task. Clinical outcome measures included the Wolf Motor Function Test (WMFT), Motor Activity Log (MAL), and functional key grip test. Transcranial magnetic stimulation (TMS) and functional magnetic resonance imaging (fMRI) were also used to map cortical areas and hemodynamic brain responses, respectively. Optical topography measurement showed an overall decrease in oxy-hemoglobin concentration in both hemispheres as therapy progressed and the laterality index increased toward the contralateral hemisphere. An increased TMS motor map area was observed in the contralateral cortex following treatment. Posttreatment fMRI showed bilateral primary motor cortex activation, although slightly greater in the contralateral hemisphere, during affected hand movement. Clinical scores revealed marked improvement in functional activities. In one patient who suffered a stroke, 2 weeks of CIT led to improved function and cortical reorganization in the hemisphere contralateral to the affected hand. PMID:15228805

  17. A longitudinal study of functional magnetic resonance imaging in upper-limb hemiplegia after stroke treated with constraint-induced movement therapy.

    PubMed

    Sheng, Bi; Lin, Ma

    2009-01-01

    To investigate the correlation of cerebral function reorganization and functional recovery by using functional magnetic resonance imaging (fMRI) with constraint-induced movement therapy (CIMT) for chronic upper-limb hemiparesis in one subject with stroke. The patient was treated with 2 weeks of CIMT and the unaffected upper-limb was restricted by a splint for 2 weeks. Clinical measures and functional magnetic resonance imaging (fMRI) tests were performed 1 day before the treatment, the day of after the treatment and 2 weeks after the treatment. Compared with the baseline, Upper Extremity Function Test (UEFT) of the patient's upper limb increased by 29.1% and Simple Test for Evaluating Hand Function (STEF) increased by 18.4%. Before, after and 2 weeks after the treatment, changes of activation in brain by using fMRI were found during the movement of the affected and unaffected hand. CIMT could significantly improve the upper limb movement function of stroke patients and fMRI proved that this kind of change was related with the plasticity change of the cerebrum. The motor function of the unaffected limb could not be affected when it was restricted and the change of the cerebrum excitation area was a transient change.

  18. Constraints to leasing and development of federal resources: OCS oil and gas and geothermal. Final report

    SciTech Connect

    Not Available

    1982-01-01

    Chapter I identifies possible technological, economic, and environmental constraints to geothermal resource development. Chapter II discusses constraints relative to outer continental shelf and geothermal resources. General leasing information for each resource is detailed. Chapter III summarizes the major studies relating to development constraints. 37 refs. (PSB)

  19. The Nature of Credit Constraints and Human Capital. NBER Working Paper No. 13912

    ERIC Educational Resources Information Center

    Lochner, Lance J.; Monge-Naranjo, Alexander

    2008-01-01

    This paper studies the nature and impact of credit constraints in the market for human capital. We derive endogenous constraints from the design of government student loan programs and from the limited repayment incentives in private lending markets. These constraints imply cross-sectional patterns for schooling, ability, and family income that…

  20. Including Overweight or Obese Students in Physical Education: A Social Ecological Constraint Model

    ERIC Educational Resources Information Center

    Li, Weidong; Rukavina, Paul

    2012-01-01

    In this review, we propose a social ecological constraint model to study inclusion of overweight or obese students in physical education by integrating key concepts and assumptions from ecological constraint theory in motor development and social ecological models in health promotion and behavior. The social ecological constraint model proposes…

  1. Including Overweight or Obese Students in Physical Education: A Social Ecological Constraint Model

    ERIC Educational Resources Information Center

    Li, Weidong; Rukavina, Paul

    2012-01-01

    In this review, we propose a social ecological constraint model to study inclusion of overweight or obese students in physical education by integrating key concepts and assumptions from ecological constraint theory in motor development and social ecological models in health promotion and behavior. The social ecological constraint model proposes…

  2. Teaching People to Manage Constraints: Effects on Creative Problem-Solving

    ERIC Educational Resources Information Center

    Peterson, David R.; Barrett, Jamie D.; Hester, Kimberly S.; Robledo, Issac C.; Hougen, Dean F.; Day, Eric A.; Mumford, Michael D.

    2013-01-01

    Constraints often inhibit creative problem-solving. This study examined the impact of training strategies for managing constraints on creative problem-solving. Undergraduates, 218 in all, were asked to work through 1 to 4 self-paced instructional programs focused on constraint management strategies. The quality, originality, and elegance of…

  3. Teaching People to Manage Constraints: Effects on Creative Problem-Solving

    ERIC Educational Resources Information Center

    Peterson, David R.; Barrett, Jamie D.; Hester, Kimberly S.; Robledo, Issac C.; Hougen, Dean F.; Day, Eric A.; Mumford, Michael D.

    2013-01-01

    Constraints often inhibit creative problem-solving. This study examined the impact of training strategies for managing constraints on creative problem-solving. Undergraduates, 218 in all, were asked to work through 1 to 4 self-paced instructional programs focused on constraint management strategies. The quality, originality, and elegance of…

  4. The Nature of Credit Constraints and Human Capital. NBER Working Paper No. 13912

    ERIC Educational Resources Information Center

    Lochner, Lance J.; Monge-Naranjo, Alexander

    2008-01-01

    This paper studies the nature and impact of credit constraints in the market for human capital. We derive endogenous constraints from the design of government student loan programs and from the limited repayment incentives in private lending markets. These constraints imply cross-sectional patterns for schooling, ability, and family income that…

  5. Locus of Control, Perceived Constraint, and Morale among Institutionalized Aged.

    ERIC Educational Resources Information Center

    Fawcett, Gayle; And Others

    1980-01-01

    Contrary to an earlier report, this study showed that life satisfaction of 56 institutionalized elderly women was associated with internality. Satisfaction was inversely related to their perception of institutional constraints, its most powerful determinant. (Author)

  6. Dark matter constraints from stellar evolution

    NASA Astrophysics Data System (ADS)

    Ayala, A.; Domínguez, I.; Straniero, O.

    2016-01-01

    The study of dark matter constraints from its effect on star evolution has been discussed in recent years. We propose a star evolution simulation approach to determine those costraints from properties related to star evolutionary stages and propose globular cluster observables in order to check those constraints. My work in progress (my PhD project research) employs FRANEC code to simulate complete star evolution from pre-main sequence to AGB phase, and regards several DM candidates like axions or WIMPs, motivated by different unsolved physical problems. Detailed energy production or energy loss due to DM particles are included, taking into account the expected interaction between dark matter particles and stellar plasma within different models.

  7. Breaking evolutionary constraint with a tradeoff ratchet

    PubMed Central

    de Vos, Marjon G. J.; Dawid, Alexandre; Sunderlikova, Vanda; Tans, Sander J.

    2015-01-01

    Epistatic interactions can frustrate and shape evolutionary change. Indeed, phenotypes may fail to evolve when essential mutations are only accessible through positive selection if they are fixed simultaneously. How environmental variability affects such constraints is poorly understood. Here, we studied genetic constraints in fixed and fluctuating environments using the Escherichia coli lac operon as a model system for genotype–environment interactions. We found that, in different fixed environments, all trajectories that were reconstructed by applying point mutations within the transcription factor–operator interface became trapped at suboptima, where no additional improvements were possible. Paradoxically, repeated switching between these same environments allows unconstrained adaptation by continuous improvements. This evolutionary mode is explained by pervasive cross-environmental tradeoffs that reposition the peaks in such a way that trapped genotypes can repeatedly climb ascending slopes and hence, escape adaptive stasis. Using a Markov approach, we developed a mathematical framework to quantify the landscape-crossing rates and show that this ratchet-like adaptive mechanism is robust in a wide spectrum of fluctuating environments. Overall, this study shows that genetic constraints can be overcome by environmental change and that cross-environmental tradeoffs do not necessarily impede but also, can facilitate adaptive evolution. Because tradeoffs and environmental variability are ubiquitous in nature, we speculate this evolutionary mode to be of general relevance. PMID:26567153

  8. Multisensory constraints on awareness.

    PubMed

    Deroy, Ophelia; Chen, Yi-Chuan; Spence, Charles

    2014-05-05

    Given that multiple senses are often stimulated at the same time, perceptual awareness is most likely to take place in multisensory situations. However, theories of awareness are based on studies and models established for a single sense (mostly vision). Here, we consider the methodological and theoretical challenges raised by taking a multisensory perspective on perceptual awareness. First, we consider how well tasks designed to study unisensory awareness perform when used in multisensory settings, stressing that studies using binocular rivalry, bistable figure perception, continuous flash suppression, the attentional blink, repetition blindness and backward masking can demonstrate multisensory influences on unisensory awareness, but fall short of tackling multisensory awareness directly. Studies interested in the latter phenomenon rely on a method of subjective contrast and can, at best, delineate conditions under which individuals report experiencing a multisensory object or two unisensory objects. As there is not a perfect match between these conditions and those in which multisensory integration and binding occur, the link between awareness and binding advocated for visual information processing needs to be revised for multisensory cases. These challenges point at the need to question the very idea of multisensory awareness.

  9. Assessment under Resource Constraints

    ERIC Educational Resources Information Center

    Lovett, Steve; Curtis, Mary G.

    2015-01-01

    Assessment and the measurement of learning are receiving increasing emphasis in American higher education. This is a case study that demonstrates a simple, inexpensive method of measuring freshman to senior "gains" or learning using a cross-sectional methodology. Seniors and freshmen within a four-year business program were both given…

  10. Multisensory constraints on awareness

    PubMed Central

    Deroy, Ophelia; Chen, Yi-Chuan; Spence, Charles

    2014-01-01

    Given that multiple senses are often stimulated at the same time, perceptual awareness is most likely to take place in multisensory situations. However, theories of awareness are based on studies and models established for a single sense (mostly vision). Here, we consider the methodological and theoretical challenges raised by taking a multisensory perspective on perceptual awareness. First, we consider how well tasks designed to study unisensory awareness perform when used in multisensory settings, stressing that studies using binocular rivalry, bistable figure perception, continuous flash suppression, the attentional blink, repetition blindness and backward masking can demonstrate multisensory influences on unisensory awareness, but fall short of tackling multisensory awareness directly. Studies interested in the latter phenomenon rely on a method of subjective contrast and can, at best, delineate conditions under which individuals report experiencing a multisensory object or two unisensory objects. As there is not a perfect match between these conditions and those in which multisensory integration and binding occur, the link between awareness and binding advocated for visual information processing needs to be revised for multisensory cases. These challenges point at the need to question the very idea of multisensory awareness. PMID:24639579

  11. Assessment under Resource Constraints

    ERIC Educational Resources Information Center

    Lovett, Steve; Curtis, Mary G.

    2015-01-01

    Assessment and the measurement of learning are receiving increasing emphasis in American higher education. This is a case study that demonstrates a simple, inexpensive method of measuring freshman to senior "gains" or learning using a cross-sectional methodology. Seniors and freshmen within a four-year business program were both given…

  12. Mars Rover Sample Return aerocapture configuration design and packaging constraints

    NASA Technical Reports Server (NTRS)

    Lawson, Shelby J.

    1989-01-01

    This paper discusses the aerodynamics requirements, volume and mass constraints that lead to a biconic aeroshell vehicle design that protects the Mars Rover Sample Return (MRSR) mission elements from launch to Mars landing. The aerodynamic requirements for Mars aerocapture and entry and packaging constraints for the MRSR elements result in a symmetric biconic aeroshell that develops a L/D of 1.0 at 27.0 deg angle of attack. A significant problem in the study is obtaining a cg that provides adequate aerodynamic stability and performance within the mission imposed constraints. Packaging methods that relieve the cg problems include forward placement of aeroshell propellant tanks and incorporating aeroshell structure as lander structure. The MRSR missions developed during the pre-phase A study are discussed with dimensional and mass data included. Further study is needed for some missions to minimize MRSR element volume so that launch mass constraints can be met.

  13. Mars Rover Sample Return aerocapture configuration design and packaging constraints

    NASA Technical Reports Server (NTRS)

    Lawson, Shelby J.

    1989-01-01

    This paper discusses the aerodynamics requirements, volume and mass constraints that lead to a biconic aeroshell vehicle design that protects the Mars Rover Sample Return (MRSR) mission elements from launch to Mars landing. The aerodynamic requirements for Mars aerocapture and entry and packaging constraints for the MRSR elements result in a symmetric biconic aeroshell that develops a L/D of 1.0 at 27.0 deg angle of attack. A significant problem in the study is obtaining a cg that provides adequate aerodynamic stability and performance within the mission imposed constraints. Packaging methods that relieve the cg problems include forward placement of aeroshell propellant tanks and incorporating aeroshell structure as lander structure. The MRSR missions developed during the pre-phase A study are discussed with dimensional and mass data included. Further study is needed for some missions to minimize MRSR element volume so that launch mass constraints can be met.

  14. Constraint elimination in dynamical systems

    NASA Technical Reports Server (NTRS)

    Singh, R. P.; Likins, P. W.

    1989-01-01

    Large space structures (LSSs) and other dynamical systems of current interest are often extremely complex assemblies of rigid and flexible bodies subjected to kinematical constraints. A formulation is presented for the governing equations of constrained multibody systems via the application of singular value decomposition (SVD). The resulting equations of motion are shown to be of minimum dimension.

  15. Constraint-Based Scheduling System

    NASA Technical Reports Server (NTRS)

    Zweben, Monte; Eskey, Megan; Stock, Todd; Taylor, Will; Kanefsky, Bob; Drascher, Ellen; Deale, Michael; Daun, Brian; Davis, Gene

    1995-01-01

    Report describes continuing development of software for constraint-based scheduling system implemented eventually on massively parallel computer. Based on machine learning as means of improving scheduling. Designed to learn when to change search strategy by analyzing search progress and learning general conditions under which resource bottleneck occurs.

  16. Financial Constraints: Explaining Your Position.

    ERIC Educational Resources Information Center

    Cargill, Jennifer

    1988-01-01

    Discusses the importance of educating library patrons about the library's finances and the impact of budget constraints and the escalating cost of serials on materials acquisition. Steps that can be taken in educating patrons by interpreting and publicizing financial information are suggested. (MES)

  17. Continuous Optimization on Constraint Manifolds

    NASA Technical Reports Server (NTRS)

    Dean, Edwin B.

    1988-01-01

    This paper demonstrates continuous optimization on the differentiable manifold formed by continuous constraint functions. The first order tensor geodesic differential equation is solved on the manifold in both numerical and closed analytic form for simple nonlinear programs. Advantages and disadvantages with respect to conventional optimization techniques are discussed.

  18. Constraints on galaxy formation theories

    NASA Technical Reports Server (NTRS)

    Szalay, A. S.

    1986-01-01

    The present theories of galaxy formation are reviewed. The relation between peculiar velocities, temperature fluctuations of the microwave background and the correlation function of galaxies point to the possibility that galaxies do not form uniformly everywhere. The velocity data provide strong constraints on the theories even in the case when light does not follow mass of the universe.

  19. Implicit Motives and Men’s Perceived Constraint in Fatherhood

    PubMed Central

    Ruppen, Jessica; Waldvogel, Patricia; Ehlert, Ulrike

    2016-01-01

    Research shows that implicit motives influence social relationships. However, little is known about their role in fatherhood and, particularly, how men experience their paternal role. Therefore, this study examined the association of implicit motives and fathers’ perceived constraint due to fatherhood. Furthermore, we explored their relation to fathers’ life satisfaction. Participants were fathers with biological children (N = 276). They were asked to write picture stories, which were then coded for implicit affiliation and power motives. Perceived constraint and life satisfaction were assessed on a visual analog scale. A higher implicit need for affiliation was significantly associated with lower perceived constraint, whereas the implicit need for power had the opposite effect. Perceived constraint had a negative influence on life satisfaction. Structural equation modeling revealed significant indirect effects of implicit affiliation and power motives on life satisfaction mediated by perceived constraint. Our findings indicate that men with a higher implicit need for affiliation experience less constraint due to fatherhood, resulting in higher life satisfaction. The implicit need for power, however, results in more perceived constraint and is related to decreased life satisfaction. PMID:27933023

  20. On handling ephemeral resource constraints in evolutionary search.

    PubMed

    Allmendinger, Richard; Knowles, Joshua

    2013-01-01

    We consider optimization problems where the set of solutions available for evaluation at any given time t during optimization is some subset of the feasible space. This model is appropriate to describe many closed-loop optimization settings (i.e., where physical processes or experiments are used to evaluate solutions) where, due to resource limitations, it may be impossible to evaluate particular solutions at particular times (despite the solutions being part of the feasible space). We call the constraints determining which solutions are non-evaluable ephemeral resource constraints (ERCs). In this paper, we investigate two specific types of ERC: one encodes periodic resource availabilities, the other models commitment constraints that make the evaluable part of the space a function of earlier evaluations conducted. In an experimental study, both types of constraint are seen to impact the performance of an evolutionary algorithm significantly. To deal with the effects of the ERCs, we propose and test five different constraint-handling policies (adapted from those used to handle standard constraints), using a number of different test functions including a fitness landscape from a real closed-loop problem. We show that knowing information about the type of resource constraint in advance may be sufficient to select an effective policy for dealing with it, even when advance knowledge of the fitness landscape is limited.

  1. Phonotactic Constraints Are Activated across Languages in Bilinguals

    PubMed Central

    Freeman, Max R.; Blumenfeld, Henrike K.; Marian, Viorica

    2016-01-01

    During spoken language comprehension, auditory input activates a bilingual’s two languages in parallel based on phonological representations that are shared across languages. However, it is unclear whether bilinguals access phonotactic constraints from the non-target language during target language processing. For example, in Spanish, words with s+ consonant onsets cannot exist, and phonotactic constraints call for epenthesis (addition of a vowel, e.g., stable/estable). Native Spanish speakers may produce English words such as estudy (“study”) with epenthesis, suggesting that these bilinguals apply Spanish phonotactic constraints when speaking English. The present study is the first to examine whether bilinguals access Spanish phonotactic constraints during English comprehension. In an English cross-modal priming lexical decision task, Spanish–English bilinguals and English monolinguals heard English cognate and non-cognate primes containing s+ consonant onsets or controls without s+ onsets, followed by a lexical decision on visual targets with the /e/ phonotactic constraint or controls without /e/. Results revealed that bilinguals were faster to respond to /es/ non-word targets preceded by s+ cognate primes and /es/ and /e/ non-word targets preceded by s+ non-cognate primes, confirming that English primes containing s+ onsets activated Spanish phonotactic constraints. These findings are discussed within current accounts of parallel activation of two languages during bilingual spoken language comprehension, which may be expanded to include activation of phonotactic constraints from the irrelevant language. PMID:27242615

  2. Architecture, constraints, and behavior

    PubMed Central

    Doyle, John C.; Csete, Marie

    2011-01-01

    This paper aims to bridge progress in neuroscience involving sophisticated quantitative analysis of behavior, including the use of robust control, with other relevant conceptual and theoretical frameworks from systems engineering, systems biology, and mathematics. Familiar and accessible case studies are used to illustrate concepts of robustness, organization, and architecture (modularity and protocols) that are central to understanding complex networks. These essential organizational features are hidden during normal function of a system but are fundamental for understanding the nature, design, and function of complex biologic and technologic systems. PMID:21788505

  3. [Niger: development under constraints].

    PubMed

    Chippaux, J P

    1998-01-01

    Several nonvenereal treponematoses are or were present in Niger while syphilis has been reported in only the northern, arid zones (Bejel) of the country. While their presence is known in Niger, endemic nonvenereal treponematoses are no longer reported by the country¿s health centers. Results are presented from a serological study using randomized Treponema pallidum Hemagglutination Assay (TPHA) upon a sample of 183 children under age 5 years old living in three areas of Niamey. No clinical exam was performed before testing. In the overall sample, 12% of tests were positive, ranging from 8% to 17% depending upon the neighborhood studied. The differences observed were insignificant according to both place of residence and age. All age groups were affected, although only 3 seropositive cases were identified among the 37 children under age 12 months. The relative levels were too high to be dismissed as serological artifacts. The most likely explanation for the high levels of antitreponemic antibodies is endemic syphilis, which is increasing in the region. Endemic syphilis is re-emerging, while penicillin is being used less systematically. Moreover, economic problems constrain access to health care. Results in children under age 12 months suggest that congenital syphilis is uncommon.

  4. Constraints based analysis of extended cybernetic models.

    PubMed

    Mandli, Aravinda R; Venkatesh, Kareenhalli V; Modak, Jayant M

    2015-11-01

    The cybernetic modeling framework provides an interesting approach to model the regulatory phenomena occurring in microorganisms. In the present work, we adopt a constraints based approach to analyze the nonlinear behavior of the extended equations of the cybernetic model. We first show that the cybernetic model exhibits linear growth behavior under the constraint of no resource allocation for the induction of the key enzyme. We then quantify the maximum achievable specific growth rate of microorganisms on mixtures of substitutable substrates under various kinds of regulation and show its use in gaining an understanding of the regulatory strategies of microorganisms. Finally, we show that Saccharomyces cerevisiae exhibits suboptimal dynamic growth with a long diauxic lag phase when growing on a mixture of glucose and galactose and discuss on its potential to achieve optimal growth with a significantly reduced diauxic lag period. The analysis carried out in the present study illustrates the utility of adopting a constraints based approach to understand the dynamic growth strategies of microorganisms.

  5. Developmental Constraints in a Wild Primate

    PubMed Central

    Lea, Amanda J.; Altmann, Jeanne; Alberts, Susan C.; Tung, Jenny

    2015-01-01

    Early-life experiences can dramatically affect adult traits. However, the evolutionary origins of such early-life effects are debated. The predictive adaptive response hypothesis argues that adverse early environments prompt adaptive phenotypic adjustments that prepare animals for similar challenges in adulthood. In contrast, the developmental constraints hypothesis argues that early adversity is generally costly. To differentiate between these hypotheses, we studied two sets of wild female baboons: those born during low-rainfall, low-quality years and those born during normal-rainfall, high-quality years. For each female, we measured fertility-related fitness components during years in adulthood that matched and mismatched her early conditions. We found support for the developmental constraints hypothesis: females born in low-quality environments showed greater decreases in fertility during drought years than females born in high-quality environments, even though drought years matched the early conditions of females born in low-quality environments. Additionally, we found that females born in low-quality years to high-status mothers did not experience reduced fertility during drought years. These results indicate that early ecological adversity did not prepare individuals to cope with ecological challenges in later life. Instead, individuals that experienced at least one high-quality early environment—either ecological or social—were more resilient to ecological stress in later life. Together, these data suggest that early adversity carries lifelong costs, which is consistent with the developmental constraints hypothesis. PMID:25996865

  6. HUBBLE PARAMETER MEASUREMENT CONSTRAINTS ON DARK ENERGY

    SciTech Connect

    Farooq, Omer; Mania, Data; Ratra, Bharat E-mail: mania@phys.ksu.edu

    2013-02-20

    We use 21 Hubble parameter versus redshift data points from Simon et al., Gaztanaga et al., Stern et al., and Moresco et al. to place constraints on model parameters of constant and time-evolving dark energy cosmologies. The inclusion of the eight new measurements results in H(z) constraints more restrictive than those derived by Chen and Ratra. These constraints are now almost as restrictive as those that follow from current Type Ia supernova (SNIa) apparent magnitude versus redshift data, which now more carefully account for systematic uncertainties. This is a remarkable result. We emphasize, however, that SNIa data have been studied for a longer time than the H(z) data, possibly resulting in a better estimate of potential systematic errors in the SNIa case. A joint analysis of the H(z), baryon acoustic oscillation peak length scale, and SNIa data favors a spatially flat cosmological model currently dominated by a time-independent cosmological constant but does not exclude slowly evolving dark energy.

  7. Constraints and spandrels of interareal connectomes

    PubMed Central

    Rubinov, Mikail

    2016-01-01

    Interareal connectomes are whole-brain wiring diagrams of white-matter pathways. Recent studies have identified modules, hubs, module hierarchies and rich clubs as structural hallmarks of these wiring diagrams. An influential current theory postulates that connectome modules are adequately explained by evolutionary pressures for wiring economy, but that the other hallmarks are not explained by such pressures and are therefore less trivial. Here, we use constraint network models to test these postulates in current gold-standard vertebrate and invertebrate interareal-connectome reconstructions. We show that empirical wiring-cost constraints inadequately explain connectome module organization, and that simultaneous module and hub constraints induce the structural byproducts of hierarchies and rich clubs. These byproducts, known as spandrels in evolutionary biology, include the structural substrate of the default-mode network. Our results imply that currently standard connectome characterizations are based on circular analyses or double dipping, and we emphasize an integrative approach to future connectome analyses for avoiding such pitfalls. PMID:27924867

  8. Constraint Theory and Roken Bond Bending Constraints in Oxide Glasses

    NASA Astrophysics Data System (ADS)

    Zhang, Min

    The molecular structure of sodium tellurate glasses was established using ^{125}Te absorption and ^{129}I emission Mossbauer spectroscopies, differential scanning calorimetry (DSC), molar volume measurements and powder x-ray diffraction (XRD). The local atomic arrangement in these glasses is found to be different from that in corresponding crystals. This picture does not follow the usual thinking (Ioffe-Regel rule) about glass structure. The experimental evidence for this conclusion derives not only from Mossbauer spectroscopy but also from time-temperature -transformation curve and powder XRD measurements used to examine the crystallization of the bulk glasses. The TTT -curve exhibits both nucleation and growth branches, while XRD scans reveal growth of metastable phases before forming the stable crystalline phases. These results are in harmony with ^{23}Na solid state NMR results that reveal that sodium local environment in a x = 0.20 glass differs qualitatively from that of the crystalline counterpart. Results from DCS and XRD measurements reveal that at x = 0.18 several observables such as, dT_{g}/dx, activation energy for enthalpy relaxation, molar volume and Lamb-Mossbauer f factor, each display a threshold behavior. We believe that the physical origin of this threshold behavior comes from the rigidity percolation threshold. The constraint theory has recently been extended to include one-fold coordinated species and broken bond bending (beta) constraints. The latter was developed and has been applied successfully to many glass systems including the oxides, as we did for the first time in our Science paper, but also to chalcogenides and chalcohalides, etc.. In the experiments, the observed threshold apparently shifts to the over-constrained regime, i.e. > 2.4 in many glass systems. This shift is largely due to broken beta -constraint at some two-fold coordinated atoms, e.g. Se/S in chain segments and oxygen atoms. An example is g-Ge _{x}Se_{1-x } where one

  9. Incorporation of phonetic constraints in acoustic-to-articulatory inversion.

    PubMed

    Potard, Blaise; Laprie, Yves; Ouni, Slim

    2008-04-01

    This study investigates the use of constraints upon articulatory parameters in the context of acoustic-to-articulatory inversion. These speaker independent constraints, referred to as phonetic constraints, were derived from standard phonetic knowledge for French vowels and express authorized domains for one or several articulatory parameters. They were experimented on in an existing inversion framework that utilizes Maeda's articulatory model and a hypercubic articulatory-acoustic table. Phonetic constraints give rise to a phonetic score rendering the phonetic consistency of vocal tract shapes recovered by inversion. Inversion has been applied to vowels articulated by a speaker whose corresponding x-ray images are also available. Constraints were evaluated by measuring the distance between vocal tract shapes recovered through inversion to real vocal tract shapes obtained from x-ray images, by investigating the spreading of inverse solutions in terms of place of articulation and constriction degree, and finally by studying the articulatory variability. Results show that these constraints capture interdependencies and synergies between speech articulators and favor vocal tract shapes close to those realized by the human speaker. In addition, this study also provides how acoustic-to-articulatory inversion can be used to explore acoustical and compensatory articulatory properties of an articulatory model.

  10. Motor abundance contributes to resolving multiple kinematic task constraints

    PubMed Central

    G, Gera; SMSF, Freitas; ML, Latash; K, Monahan; G, Schöner; JP, Scholz

    2009-01-01

    This study investigated the use of motor abundance during the transport and placing of objects that required either precise or minimal orientation to the target. Analyses across repetitions of the structure of joint configuration variance relative to the position and orientation constraints were performed using the Uncontrolled Manifold (UCM) approach. Results indicated that the orientation constraint did not affect stability of the hand's spatial trajectory. Orientation was weakly stabilized during the late transport phase independent of the orientation constraint, indicating no default synergy stabilizing orientation. Stabilization of orientation for conditions most requiring it for successful insertion of the object was present primarily during the adjustment phase. The results support the hypothesis that a major advantage of a control scheme that utilizes motor abundance is the ability to resolve multiple task constraints simultaneously without undue interference among them. PMID:20237405

  11. Sensitivity of Lumped Constraints Using the Adjoint Method

    NASA Technical Reports Server (NTRS)

    Akgun, Mehmet A.; Haftka, Raphael T.; Wu, K. Chauncey; Walsh, Joanne L.

    1999-01-01

    Adjoint sensitivity calculation of stress, buckling and displacement constraints may be much less expensive than direct sensitivity calculation when the number of load cases is large. Adjoint stress and displacement sensitivities are available in the literature. Expressions for local buckling sensitivity of isotropic plate elements are derived in this study. Computational efficiency of the adjoint method is sensitive to the number of constraints and, therefore, the method benefits from constraint lumping. A continuum version of the Kreisselmeier-Steinhauser (KS) function is chosen to lump constraints. The adjoint and direct methods are compared for three examples: a truss structure, a simple HSCT wing model, and a large HSCT model. These sensitivity derivatives are then used in optimization.

  12. Dual MIMU Pedestrian Navigation by Inequality Constraint Kalman Filtering.

    PubMed

    Shi, Wei; Wang, Yang; Wu, Yuanxin

    2017-02-22

    The foot-mounted inertial navigation system is an important method of pedestrian navigation as it, in principle, does not rely any external assistance. A real-time range decomposition constraint method is proposed in this paper to combine the information of dual foot-mounted inertial navigation systems. It is well known that low-cost inertial pedestrian navigation aided with both ZUPT (zero velocity update) and the range decomposition constraint performs better than those in their own respective methods. This paper recommends that the separation distance between the position estimates of the two foot-mounted inertial navigation systems be restricted by an ellipsoidal constraint that relates to the maximum step length and the leg height. The performance of the proposed method is studied by utilizing experimental data, and the results indicate that the method can effectively correct the dual navigation systems' position over the traditional spherical constraint.

  13. Dual MIMU Pedestrian Navigation by Inequality Constraint Kalman Filtering

    PubMed Central

    Shi, Wei; Wang, Yang; Wu, Yuanxin

    2017-01-01

    The foot-mounted inertial navigation system is an important method of pedestrian navigation as it, in principle, does not rely any external assistance. A real-time range decomposition constraint method is proposed in this paper to combine the information of dual foot-mounted inertial navigation systems. It is well known that low-cost inertial pedestrian navigation aided with both ZUPT (zero velocity update) and the range decomposition constraint performs better than those in their own respective methods. This paper recommends that the separation distance between the position estimates of the two foot-mounted inertial navigation systems be restricted by an ellipsoidal constraint that relates to the maximum step length and the leg height. The performance of the proposed method is studied by utilizing experimental data, and the results indicate that the method can effectively correct the dual navigation systems’ position over the traditional spherical constraint. PMID:28241448

  14. Functional constraints on phenomenological coefficients

    NASA Astrophysics Data System (ADS)

    Klika, Václav; Pavelka, Michal; Benziger, Jay B.

    2017-02-01

    Thermodynamic fluxes (diffusion fluxes, heat flux, etc.) are often proportional to thermodynamic forces (gradients of chemical potentials, temperature, etc.) via the matrix of phenomenological coefficients. Onsager's relations imply that the matrix is symmetric, which reduces the number of unknown coefficients is reduced. In this article we demonstrate that for a class of nonequilibrium thermodynamic models in addition to Onsager's relations the phenomenological coefficients must share the same functional dependence on the local thermodynamic state variables. Thermodynamic models and experimental data should be validated through consistency with the functional constraint. We present examples of coupled heat and mass transport (thermodiffusion) and coupled charge and mass transport (electro-osmotic drag). Additionally, these newly identified constraints further reduce the number of experiments needed to describe the phenomenological coefficient.

  15. A compendium of chameleon constraints

    NASA Astrophysics Data System (ADS)

    Burrage, Clare; Sakstein, Jeremy

    2016-11-01

    The chameleon model is a scalar field theory with a screening mechanism that explains how a cosmologically relevant light scalar can avoid the constraints of intra-solar-system searches for fifth-forces. The chameleon is a popular dark energy candidate and also arises in f(R) theories of gravity. Whilst the chameleon is designed to avoid historical searches for fifth-forces it is not unobservable and much effort has gone into identifying the best observables and experiments to detect it. These results are not always presented for the same models or in the same language, a particular problem when comparing astrophysical and laboratory searches making it difficult to understand what regions of parameter space remain. Here we present combined constraints on the chameleon model from astrophysical and laboratory searches for the first time and identify the remaining windows of parameter space. We discuss the implications for cosmological chameleon searches and future small-scale probes.

  16. Integral Constraints and MHD Stability

    NASA Astrophysics Data System (ADS)

    Jensen, T. H.

    2003-10-01

    Determining stability of a plasma in MHD equilibrium, energetically isolated by a conducting wall, requires an assumption on what governs the dynamics of the plasma. One example is the assumption that the plasma obeys ideal MHD, leading to the well known ``δ W" criteria [I. Bernstein, et al., Proc. Roy. Soc. London A244, 17 (1958)]. A radically different approach was used by Taylor [J.B. Taylor, Rev. Mod. Phys. 58, 741 (1986)] in assuming that the dynamics of the plasma is restricted only by the requirement that helicity, an integral constant associated with the plasma, is conserved. The relevancy of Taylor's assumption is supported by the agreement between resulting theoretical results and experimental observations. Another integral constraint involves the canonical angular momentum of the plasma particles. One consequence of using this constraint is that tokamak plasmas have no poloidal current in agreement with some current hole tokamak observations [T.H. Jensen, Phys. Lett. A 305, 183 (2002)].

  17. Constraint checking during error recovery

    NASA Technical Reports Server (NTRS)

    Lutz, Robyn R.; Wong, Johnny S. K.

    1993-01-01

    The system-level software onboard a spacecraft is responsible for recovery from communication, power, thermal, and computer-health anomalies that may occur. The recovery must occur without disrupting any critical scientific or engineering activity that is executing at the time of the error. Thus, the error-recovery software may have to execute concurrently with the ongoing acquisition of scientific data or with spacecraft maneuvers. This work provides a technique by which the rules that constrain the concurrent execution of these processes can be modeled in a graph. An algorithm is described that uses this model to validate that the constraints hold for all concurrent executions of the error-recovery software with the software that controls the science and engineering activities of the spacecraft. The results are applicable to a variety of control systems with critical constraints on the timing and ordering of the events they control.

  18. Managing Restaurant Tables using Constraints

    NASA Astrophysics Data System (ADS)

    Vidotto, Alfio; Brown, Kenneth N.; Beck, J. Christopher

    Restaurant table management can have significant impact on both profitability and the customer experience. The core of the issue is a complex dynamic combinatorial problem. We show how to model the problem as constraint satisfaction, with extensions which generate flexible seating plans and which maintain stability when changes occur. We describe an implemented system which provides advice to users in real time. The system is currently being evaluated in a restaurant environment.

  19. Macroscopic constraints on string unification

    SciTech Connect

    Taylor, T.R.

    1989-03-01

    The comparison of sting theory with experiment requires a huge extrapolation from the microscopic distances, of order of the Planck length, up to the macroscopic laboratory distances. The quantum effects give rise to large corrections to the macroscopic predictions of sting unification. I discus the model-independent constraints on the gravitational sector of string theory due to the inevitable existence of universal Fradkin-Tseytlin dilatons. 9 refs.

  20. Counting Heron Triangles with Constraints

    DTIC Science & Technology

    2013-01-25

    A3 INTEGERS 13 (2013) COUNTING HERON TRIANGLES WITH CONSTRAINTS Pantelimon Stănică Applied Mathematics, Naval Postgraduate School, Monterey...12, Revised: 10/12/12, Accepted: 1/13/13, Published: 1/25/13 Abstract Heron triangles have the property that all three of their sides as well as their...area are positive integers. In this paper, we give some estimates for the number of Heron triangles with two of their sides fixed. We provide a

  1. Adaptive Search through Constraint Violations

    DTIC Science & Technology

    1990-01-01

    ZIP Code) 3939 O’Hara Street 800 North Quincy Street Pittsburgh, PA 15260 Arlington, VA 22217-5000 8a NAME OF FUNDING/SPONSORING Bb OFFICE SYMBOL 9...Pittsburgh, PA . Smith, D. A., Greeno, J. G., & Vitolo, T. M., (in press). A model of competence for counting. Cognitive Science. VanLehn, K. (in press...1990). Adaptive search through constraint violations (Technical Report No. KUL-90-01). Pittsburgh, PA : Learning Research and Development Center

  2. Virasoro constraint for Nekrasov instanton partition function

    NASA Astrophysics Data System (ADS)

    Kanno, Shoichi; Matsuo, Yutaka; Zhang, Hong

    2012-10-01

    We show that Nekrasov instanton partition function for SU( N ) gauge theories satisfies recursion relations in the form of U(1)+Virasoro constraints when β = 1. The constraints give a direct support for AGT conjecture for general quiver gauge theories.

  3. Infrared constraints on ultraviolet theories

    NASA Astrophysics Data System (ADS)

    Tsai, Yuhsin

    2012-01-01

    While our current paradigm of particle physics, the Standard Model (SM), has been extremely successful at explaining experiments, it is theoretically incomplete and must be embedded into a larger framework. In this thesis, we review the main motivations for theories beyond the SM (BSM) and the ways such theories can be constrained using low energy physics. The hierarchy problem, neutrino mass and the existence of dark matter (DM) are the main reasons why the SM is incomplete . Two of the most plausible theories that may solve the hierarchy problem are the Randall-Sundrum (RS) models and supersymmetry (SUSY). RS models usually suffer from strong flavor constraints, while SUSY models produce extra degrees of freedom that need to be hidden from current experiments. To show the importance of infrared (IR) physics constraints, we discuss the flavor bounds on the anarchic RS model in both the lepton and quark sectors. For SUSY models, we discuss the difficulties in obtaining a phenomenologically allowed gaugino mass, its relation to R-symmetry breaking, and how to build a model that avoids this problem. For the neutrino mass problem, we discuss the idea of generating small neutrino masses using compositeness. By requiring successful leptogenesis and the existence of warm dark matter (WDM), we can set various constraints on the hidden composite sector. Finally, to give an example of model independent bounds from collider experiments, we show how to constrain the DM-SM particle interactions using collider results with an effective coupling description.

  4. Constraint Based Modeling Going Multicellular.

    PubMed

    Martins Conde, Patricia do Rosario; Sauter, Thomas; Pfau, Thomas

    2016-01-01

    Constraint based modeling has seen applications in many microorganisms. For example, there are now established methods to determine potential genetic modifications and external interventions to increase the efficiency of microbial strains in chemical production pipelines. In addition, multiple models of multicellular organisms have been created including plants and humans. While initially the focus here was on modeling individual cell types of the multicellular organism, this focus recently started to switch. Models of microbial communities, as well as multi-tissue models of higher organisms have been constructed. These models thereby can include different parts of a plant, like root, stem, or different tissue types in the same organ. Such models can elucidate details of the interplay between symbiotic organisms, as well as the concerted efforts of multiple tissues and can be applied to analyse the effects of drugs or mutations on a more systemic level. In this review we give an overview of the recent development of multi-tissue models using constraint based techniques and the methods employed when investigating these models. We further highlight advances in combining constraint based models with dynamic and regulatory information and give an overview of these types of hybrid or multi-level approaches.

  5. Infrared Constraint on Ultraviolet Theories

    SciTech Connect

    Tsai, Yuhsin

    2012-08-01

    While our current paradigm of particle physics, the Standard Model (SM), has been extremely successful at explaining experiments, it is theoretically incomplete and must be embedded into a larger framework. In this thesis, we review the main motivations for theories beyond the SM (BSM) and the ways such theories can be constrained using low energy physics. The hierarchy problem, neutrino mass and the existence of dark matter (DM) are the main reasons why the SM is incomplete . Two of the most plausible theories that may solve the hierarchy problem are the Randall-Sundrum (RS) models and supersymmetry (SUSY). RS models usually suffer from strong flavor constraints, while SUSY models produce extra degrees of freedom that need to be hidden from current experiments. To show the importance of infrared (IR) physics constraints, we discuss the flavor bounds on the anarchic RS model in both the lepton and quark sectors. For SUSY models, we discuss the difficulties in obtaining a phenomenologically allowed gaugino mass, its relation to R-symmetry breaking, and how to build a model that avoids this problem. For the neutrino mass problem, we discuss the idea of generating small neutrino masses using compositeness. By requiring successful leptogenesis and the existence of warm dark matter (WDM), we can set various constraints on the hidden composite sector. Finally, to give an example of model independent bounds from collider experiments, we show how to constrain the DM–SM particle interactions using collider results with an effective coupling description.

  6. Constraints influencing sports wheelchair propulsion performance and injury risk

    PubMed Central

    2013-01-01

    The Paralympic Games are the pinnacle of sport for many athletes with a disability. A potential issue for many wheelchair athletes is how to train hard to maximise performance while also reducing the risk of injuries, particularly to the shoulder due to the accumulation of stress placed on this joint during activities of daily living, training and competition. The overall purpose of this narrative review was to use the constraints-led approach of dynamical systems theory to examine how various constraints acting upon the wheelchair-user interface may alter hand rim wheelchair performance during sporting activities, and to a lesser extent, their injury risk. As we found no studies involving Paralympic athletes that have directly utilised the dynamical systems approach to interpret their data, we have used this approach to select some potential constraints and discussed how they may alter wheelchair performance and/or injury risk. Organism constraints examined included player classifications, wheelchair setup, training and intrinsic injury risk factors. Task constraints examined the influence of velocity and types of locomotion (court sports vs racing) in wheelchair propulsion, while environmental constraints focused on forces that tend to oppose motion such as friction and surface inclination. Finally, the ecological validity of the research studies assessing wheelchair propulsion was critiqued prior to recommendations for practice and future research being given. PMID:23557065

  7. A Hybrid Constraint Representation and Reasoning Framework

    NASA Technical Reports Server (NTRS)

    Golden, Keith; Pang, Wanlin

    2004-01-01

    In this paper, we introduce JNET, a novel constraint representation and reasoning framework that supports procedural constraints and constraint attachments, providing a flexible way of integrating the constraint system with a runtime software environment and improving its applicability. We describe how JNET is applied to a real-world problem - NASA's Earth-science data processing domain, and demonstrate how JNET can be extended, without any knowledge of how it is implemented, to meet the growing demands of real-world applications.

  8. Democratic constraints on demographic policy.

    PubMed

    Grigsby, J S

    1984-01-01

    The discussion compares the population policies adopted in Sweden during the 1930s to raise fertiity and the policies considered in the US during the 1970s in response to the high fertility experienced in the 1950s. Both sets of policies recommended increased availability of birth control, more liberal abortion laws, and greater employment opportunities for women. It becomes evident that the constraints imposed by a democratic system of government translate into policy recommendations that place individual freedom of choice and equal opportunity for all citizens as higher goals than any specific demographic target. Consequently, the population commissions of Sweden and the US made similar suggestions on how to resolve their opposite demographic problems. The demographic situations in the 2 nations were antipodal, and the countries also had very different social climates. This additional disparity was insufficient to counterbalance the apparently overwhelming influence of the democratic political systems in making virtually identical policy recommendations. Yet, the contrasting social climates of Sweden in 1935 and the US in 1970-72 may explain the different reactions each commission received. In terms of the responses by both citizens and government officials to the commissions' reports, the Swedish commission was more successful. Practically all of their recommendations were enthusiastically received and quickly adopted by the Swedish Riksdag. Yet, when the criterion for success becomes whether or not a demographic target was met, it increased in the 1940s and then dropped again while the same social policies were in effect. Even before the US commission began its study, fertility in the US had fallen and continues to remain low. These findings suggest that commissions in democratic countries will most likely never recommend dramatic measures in population policy. Thus, it is questionable whether such commissions in democratic nations will totally fulfill the

  9. Learning and Parallelization Boost Constraint Search

    ERIC Educational Resources Information Center

    Yun, Xi

    2013-01-01

    Constraint satisfaction problems are a powerful way to abstract and represent academic and real-world problems from both artificial intelligence and operations research. A constraint satisfaction problem is typically addressed by a sequential constraint solver running on a single processor. Rather than construct a new, parallel solver, this work…

  10. Learning and Parallelization Boost Constraint Search

    ERIC Educational Resources Information Center

    Yun, Xi

    2013-01-01

    Constraint satisfaction problems are a powerful way to abstract and represent academic and real-world problems from both artificial intelligence and operations research. A constraint satisfaction problem is typically addressed by a sequential constraint solver running on a single processor. Rather than construct a new, parallel solver, this work…

  11. Design of helicopter rotors to noise constraints

    NASA Technical Reports Server (NTRS)

    Schaeffer, E. G.; Sternfeld, H., Jr.

    1978-01-01

    Results of the initial phase of a research project to study the design constraints on helicopter noise are presented. These include the calculation of nonimpulsive rotor harmonic and broadband hover noise spectra, over a wide range of rotor design variables and the sensitivity of perceived noise level (PNL) to changes in rotor design parameters. The prediction methodology used correlated well with measured whirl tower data. Application of the predictions to variations in rotor design showed tip speed and thrust as having the most effect on changing PNL.

  12. Chemical Constraints on the Early Solar System

    NASA Technical Reports Server (NTRS)

    Wyckoff, Susan

    2004-01-01

    Chemical abundances of comets and star-forming regions provide p o w d clues to the conditions which prevailed in the outer solar nebula. Hence comparative spectroscopic studies of cometary and molecular cloud gases provide vital insights into conditions in the solar protoplanetary disk at heliocentric distances beyond 5 AU 4.6 Gyr ago. We proposed a research program which combined optical and sub-millimeter techniques with laboratory spectroscopy, and sought to determine key diagnostic constraints on single-star protoplanetary disk models.

  13. Constraints on global fire activity vary across a resource gradient.

    PubMed

    Krawchuk, Meg A; Moritz, Max A

    2011-01-01

    We provide an empirical, global test of the varying constraints hypothesis, which predicts systematic heterogeneity in the relative importance of biomass resources to burn and atmospheric conditions suitable to burning (weather/climate) across a spatial gradient of long-term resource availability. Analyses were based on relationships between monthly global wildfire activity, soil moisture, and mid-tropospheric circulation data from 2001 to 2007, synthesized across a gradient of long-term averages in resources (net primary productivity), annual temperature, and terrestrial biome. We demonstrate support for the varying constraints hypothesis, showing that, while key biophysical factors must coincide for wildfires to occur, the relative influence of resources to burn and moisture/weather conditions on fire activity shows predictable spatial patterns. In areas where resources are always available for burning during the fire season, such as subtropical/tropical biomes with mid-high annual long-term net primary productivity, fuel moisture conditions exert their strongest constraint on fire activity. In areas where resources are more limiting or variable, such as deserts, xeric shrublands, or grasslands/savannas, fuel moisture has a diminished constraint on wildfire, and metrics indicating availability of burnable fuels produced during the antecedent wet growing seasons reflect a more pronounced constraint on wildfire. This macro-scaled evidence for spatially varying constraints provides a synthesis with studies performed at local and regional scales, enhances our understanding of fire as a global process, and indicates how sensitivity to future changes in temperature and precipitation may differ across the world.

  14. Social constraints, genetic vulnerability, and mental health following collective stress.

    PubMed

    Holman, E Alison; Lucas-Thompson, Rachel G; Lu, Tammy

    2011-10-01

    A repeat-length polymorphism of the serotonin promoter gene (5-HTTLPR) has been associated with depression and posttraumatic stress disorder (PTSD) in trauma-exposed individuals reporting unsupportive social environments. We examine the contributions of the triallelic 5-HTTLPR genotype and social constraints to posttraumatic stress (PTS) symptoms in a national sample following the September 11, 2001 (9/11) terrorist attacks. Saliva was collected by mail from 711 respondents (European American subsample n = 463) of a large national probability sample of 2,729 adults. Respondents completed web-based assessments of pre-9/11 mental and physical health, acute stress 9 to 23 days post-9/11, PTS symptoms, and social constraints on disclosure regarding fears of future terrorist attacks 2-3 years post-9/11. Social constraints were positively associated with PTS symptoms 2-3 years post-9/11. The triallelic 5-HTTLPR genotype was not directly associated with PTS symptoms, but it interacted with social constraints to predict PTS symptoms 2-3 years post-9/11: Social constraints were more strongly associated with PTS symptoms for individuals with any s/lg allele than for homozygous la/la individuals. Constraints on disclosing fears about future terrorism moderate the 5-HTTLPR genotype-PTS symptom association even when indirectly exposed to collective stress. Copyright © 2011 International Society for Traumatic Stress Studies.

  15. Optical mechanical analogy and nonlinear nonholonomic constraints.

    PubMed

    Bloch, Anthony M; Rojo, Alberto G

    2016-02-01

    In this paper we establish a connection between particle trajectories subject to a nonholonomic constraint and light ray trajectories in a variable index of refraction. In particular, we extend the analysis of systems with linear nonholonomic constraints to the dynamics of particles in a potential subject to nonlinear velocity constraints. We contrast the long time behavior of particles subject to a constant kinetic energy constraint (a thermostat) to particles with the constraint of parallel velocities. We show that, while in the former case the velocities of each particle equalize in the limit, in the latter case all the kinetic energies of each particle remain the same.

  16. Resolving manipulator redundancy under inequality constraints

    SciTech Connect

    Cheng, F.T.; Chen, T.H.; Sun, Y.Y. . Dept. of Electrical Engineering)

    1994-02-01

    Due to hardware limitations, physical constraints such as joint rate bounds, joint angle limits, and joint torque constraints always exist. In this paper, these constraints are considered into the general formulation of the redundant inverse kinematic problem. To take these physical constraints into account, the computationally efficient Compact Quadratic Programming (QP) method is formed to resolve the constrained kinematic redundancy problem. In addition, the Compact-Inverse QP method is also formulated to remedy the unescapable singularity problem with inequality constraints. Two examples are given to demonstrate the generality and superiority of these two methods: to eliminate the drift phenomenon caused by self motion and to remedy saturation-type nonlinearity problem.

  17. Stochastic population dynamics under resource constraints

    NASA Astrophysics Data System (ADS)

    Gavane, Ajinkya S.; Nigam, Rahul

    2016-06-01

    This paper investigates the population growth of a certain species in which every generation reproduces thrice over a period of predefined time, under certain constraints of resources needed for survival of population. We study the survival period of a species by randomizing the reproduction probabilities within a window at same predefined ages and the resources are being produced by the working force of the population at a variable rate. This randomness in the reproduction rate makes the population growth stochastic in nature and one cannot predict the exact form of evolution. Hence we study the growth by running simulations for such a population and taking an ensemble averaged over 500 to 5000 such simulations as per the need. While the population reproduces in a stochastic manner, we have implemented a constraint on the amount of resources available for the population. This is important to make the simulations more realistic. The rate of resource production then is tuned to find the rate which suits the survival of the species. We also compute the mean life time of the species corresponding to different resource production rate. Study for these outcomes in the parameter space defined by the reproduction probabilities and rate of resource production is carried out.

  18. Stochastic population dynamics under resource constraints

    SciTech Connect

    Gavane, Ajinkya S. Nigam, Rahul

    2016-06-02

    This paper investigates the population growth of a certain species in which every generation reproduces thrice over a period of predefined time, under certain constraints of resources needed for survival of population. We study the survival period of a species by randomizing the reproduction probabilities within a window at same predefined ages and the resources are being produced by the working force of the population at a variable rate. This randomness in the reproduction rate makes the population growth stochastic in nature and one cannot predict the exact form of evolution. Hence we study the growth by running simulations for such a population and taking an ensemble averaged over 500 to 5000 such simulations as per the need. While the population reproduces in a stochastic manner, we have implemented a constraint on the amount of resources available for the population. This is important to make the simulations more realistic. The rate of resource production then is tuned to find the rate which suits the survival of the species. We also compute the mean life time of the species corresponding to different resource production rate. Study for these outcomes in the parameter space defined by the reproduction probabilities and rate of resource production is carried out.

  19. Using Formative Assessment Despite the Constraints of High Stakes Testing and Limited Resources: A Case Study of Chemistry Teachers in Anglophone Cameroon

    ERIC Educational Resources Information Center

    Akom, George Viche

    2010-01-01

    Formative assessment, as a strategy used to improve student learning, encounters several obstacles in its implementation. This study explores changes in teachers' views and practices as they are introduced to formative assessment in a high stakes testing and limited resource environment. The study examines the extent to which teachers use the…

  20. Constraints on the timeon model

    NASA Astrophysics Data System (ADS)

    Araki, Takeshi; Geng, C. Q.

    2009-04-01

    The timeon model recently proposed by Friedberg and Lee has a potential problem of flavor changing neutral currents (FCNCs) if the mass of the timeon is small. In order to avoid, we introduce a small dimensionless parameter to suppress FCNCs. Even in this case, we find that the timeon mass must be larger than 151 GeV to satisfy all the constraints from processes involving FCNCs in the quark sectors. We also extend the timeon model to the lepton sector and examine the leptonic processes.

  1. Trajectory constraints in qualitative simulation

    SciTech Connect

    Brajnik, G.; Clancy, D.J.

    1996-12-31

    We present a method for specifying temporal constraints on trajectories of dynamical systems and enforcing them during qualitative simulation. This capability can be used to focus a simulation, simulate non-autonomous and piecewise-continuous systems, reason about boundary condition problems and incorporate observations into the simulation. The method has been implemented in TeQSIM, a qualitative simulator that combines the expressive power of qualitative differential equations with temporal logic. It interleaves temporal logic model checking with the simulation to constrain and refine the resulting predicted behaviors and to inject discontinuous changes into the simulation.

  2. Killing symmetries as Hamiltonian constraints

    NASA Astrophysics Data System (ADS)

    Lusanna, Luca

    2016-02-01

    The existence of a Killing symmetry in a gauge theory is equivalent to the addition of extra Hamiltonian constraints in its phase space formulation, which imply restrictions both on the Dirac observables (the gauge invariant physical degrees of freedom) and on the gauge freedom. When there is a time-like Killing vector field only pure gauge electromagnetic fields survive in Maxwell theory in Minkowski space-time, while in ADM canonical gravity in asymptotically Minkowskian space-times only inertial effects without gravitational waves survive.

  3. QPO Constraints on Neutron Stars

    NASA Technical Reports Server (NTRS)

    Miller, M. Coleman

    2005-01-01

    The kilohertz frequencies of QPOs from accreting neutron star systems imply that they are generated in regions of strong gravity, close to the star. This suggests that observations of the QPOs can be used to constrain the properties of neutron stars themselves, and in particular to inform us about the properties of cold matter beyond nuclear densities. Here we discuss some relatively model-insensitive constraints that emerge from the kilohertz QPOs, as well as recent developments that may hint at phenomena related to unstable circular orbits outside neutron stars.

  4. Closure constraints for hyperbolic tetrahedra

    NASA Astrophysics Data System (ADS)

    Charles, Christoph; Livine, Etera R.

    2015-07-01

    We investigate the generalization of loop gravity's twisted geometries to a q-deformed gauge group. In the standard undeformed case, loop gravity is a formulation of general relativity as a diffeomorphism-invariant SU(2) gauge theory. Its classical states are graphs provided with algebraic data. In particular, closure constraints at every node of the graph ensure their interpretation as twisted geometries. Dual to each node, one has a polyhedron embedded in flat space {{{R}}3}. One then glues them, allowing for both curvature and torsion. It was recently conjectured that q-deforming the gauge group SU(2) would allow us to account for a non-vanishing cosmological constant Λ \

  5. Cognitive constraints on motor imagery.

    PubMed

    Dahm, Stephan F; Rieger, Martina

    2016-03-01

    Executed bimanual movements are prepared slower when moving to symbolically different than when moving to symbolically same targets and when targets are mapped to target locations in a left/right fashion than when they are mapped in an inner/outer fashion [Weigelt et al. (Psychol Res 71:238-447, 2007)]. We investigated whether these cognitive bimanual coordination constraints are observable in motor imagery. Participants performed fast bimanual reaching movements from start to target buttons. Symbolic target similarity and mapping were manipulated. Participants performed four action conditions: one execution and three imagination conditions. In the latter they indicated starting, ending, or starting and ending of the movement. We measured movement preparation (RT), movement execution (MT) and the combined duration of movement preparation and execution (RTMT). In all action conditions RTs and MTs were longer in movements towards different targets than in movements towards same targets. Further, RTMTs were longer when targets were mapped to target locations in a left/right fashion than when they were mapped in an inner/outer fashion, again in all action conditions. RTMTs in imagination and execution were similar, apart from the imagination condition in which participants indicated the start and the end of the movement. Here MTs, but not RTs, were longer than in the execution condition. In conclusion, cognitive coordination constraints are present in the motor imagery of fast (<1600 ms) bimanual movements. Further, alternations between inhibition and execution may prolong the duration of motor imagery.

  6. System Constraints on Efficacious Teacher Behaviours in School-Based Suicide Prevention Initiatives; A Qualitative Study of Teacher Views and Experiences

    ERIC Educational Resources Information Center

    McConnellogue, Sheila; Storey, Lesley

    2017-01-01

    International concern about youth suicide has led to a growing consensus that schools are a potentially important location for suicide prevention efforts. The present study investigated the experiences and perceptions of teachers regarding a role in youth suicide prevention through semi-structured interviews which were analysed using…

  7. Exploring Support for the Extracurriculum in a Time of Fiscal Constraint and Standards-Based Reform: A Case Study of One Pennsylvania School District

    ERIC Educational Resources Information Center

    Murphy, Mark Patrick

    2012-01-01

    Although much has been researched and written about the value of extracurricular programs in U.S. public schools, few studies have addressed the combined effect that school reform initiatives, including myriad standardized tests, accountability measures, and massive financial crisis which have become more commonplace during periods of economic…

  8. Revealing Communication Constraints in Extension Communication Strategies: A Case Study of a Project under the World Bank's T & V System, India.

    ERIC Educational Resources Information Center

    Melkote, Srinivas R.

    A study looked at an agricultural extension project in south India to examine comprehension of the extension team's intentionality by the poorest farmers. Subjects, 50 farmers in the village of Porandla in the state of Andhra Pradesh, were interviewed and measured to see if their knowledge and comprehension approximated a constant across all…

  9. Exploring the added value of imposing an ozone effect monotonicity constraint and of jointly modeling ozone and temperature effects in an epidemiologic study of air pollution and mortality

    EPA Science Inventory

    Abstract: A number of epidemiologic studies have shown that both ozone and temperature are associated with increased risk for cardio-respiratory mortality and morbidity. However, their joint effects are not characterized as well as their independent effects. Furthermore, the i...

  10. Exploring the added value of imposing an ozone effect monotonicity constraint and of jointly modeling ozone and temperature effects in an epidemiologic study of air pollution and mortality

    EPA Science Inventory

    Abstract: A number of epidemiologic studies have shown that both ozone and temperature are associated with increased risk for cardio-respiratory mortality and morbidity. However, their joint effects are not characterized as well as their independent effects. Furthermore, the i...

  11. Reformulating Constraints for Compilability and Efficiency

    NASA Technical Reports Server (NTRS)

    Tong, Chris; Braudaway, Wesley; Mohan, Sunil; Voigt, Kerstin

    1992-01-01

    KBSDE is a knowledge compiler that uses a classification-based approach to map solution constraints in a task specification onto particular search algorithm components that will be responsible for satisfying those constraints (e.g., local constraints are incorporated in generators; global constraints are incorporated in either testers or hillclimbing patchers). Associated with each type of search algorithm component is a subcompiler that specializes in mapping constraints into components of that type. Each of these subcompilers in turn uses a classification-based approach, matching a constraint passed to it against one of several schemas, and applying a compilation technique associated with that schema. While much progress has occurred in our research since we first laid out our classification-based approach [Ton91], we focus in this paper on our reformulation research. Two important reformulation issues that arise out of the choice of a schema-based approach are: (1) compilability-- Can a constraint that does not directly match any of a particular subcompiler's schemas be reformulated into one that does? and (2) Efficiency-- If the efficiency of the compiled search algorithm depends on the compiler's performance, and the compiler's performance depends on the form in which the constraint was expressed, can we find forms for constraints which compile better, or reformulate constraints whose forms can be recognized as ones that compile poorly? In this paper, we describe a set of techniques we are developing for partially addressing these issues.

  12. "Miss, How do you Write Hipotesis?" Learning to Teach Science to English Language Learners While Navigating Affordances and Constraints: A Longitudinal Multiple Case Study

    NASA Astrophysics Data System (ADS)

    Ortega, Irasema

    Early career science teachers are often assigned to classrooms with high numbers of English language learners (ELL students). As these teachers learn to become effective practitioners, the circumstances surrounding them merit a thorough examination. This study examines the longitudinal changes in Pedagogical Content Knowledge (PCK) and practices of six early career science teachers who taught in urban schools. The teachers participated in the Alternative Support for Induction Science Teachers (ASIST) program during their initial two years of teaching. Our research team followed the participants over a five-year period. This study focuses on data from Years 1, 3, and 5. The data collected included classroom observations and interviews. In addition, classroom artifacts were collected periodically for the purpose of triangulation. The analysis of the data revealed that with the support of the ASIST program, the teachers implemented inquiry lessons and utilized instructional materials that promoted academic language skills and science competencies among their ELL students. Conversely, standardized testing, teaching assignment, and school culture played a role in constraining the implementation of inquiry-based practices. The results of this study call for collaborative efforts among university science educators and school administrators to provide professional development opportunities and support for the implementation of inquiry and language practices among early career science teachers of ELL students.

  13. Constraints on formation processes of two coarse-grained calcium- aluminum-rich inclusions: a study of mantles, islands and cores

    USGS Publications Warehouse

    Meeker, G.P.

    1995-01-01

    Many coarse-grained calcium- aluminum-rich inclusions (CAIs) contain features that are inconsistent with equilibrium liquid crystallization models of origin. Spinel-free islands (SFIs) in spinel-rich cores of Type B CAIs are examples of such features. One model previously proposed for the origin of Allende 5241, a Type B1 CAI containing SFIs, involves the capture and assimilation of xenoliths by a liquid droplet in the solar nebula (El Goresy et al, 1985; MacPherson et al 1989). This study reports new textural and chemical zoning data from 5241 and identifies previously unrecognized chemical zoning patterns in the melilite mantle and in a SFI. -from Author

  14. Observational constraints on assisted k-inflation

    SciTech Connect

    Ohashi, Junko; Tsujikawa, Shinji

    2011-05-15

    We study observational constraints on the assisted k-inflation models in which multiple scalar fields join an attractor characterized by an effective single field {phi}. This effective single-field system is described by the Lagrangian P=Xg(Y), where X is the kinetic energy of {phi}, {lambda} is a constant, and g is an arbitrary function in terms of Y=Xe{sup {lambda}{phi}}. Our analysis covers a wide variety of k-inflation models such as dilatonic ghost condensate, Dirac-Born-Infeld field, and tachyon, as well as the canonical field with an exponential potential. We place observational bounds on the parameters of each model from the WMAP 7yr data combined with baryon acoustic oscillations and the Hubble constant measurement. Using the observational constraints of the equilateral non-Gaussianity parameter f{sub NL}{sup equil}, we further restrict the allowed parameter space of dilatonic ghost condensate and Dirac-Born-Infeld models. We extend the analysis to more general models with several different choices of g(Y) and show that the models such as g(Y)=c{sub 0}+c{sub p}Y{sup p} (p{>=}3) are excluded by the joint data analysis of the scalar/tensor spectra and primordial non-Gaussianities.

  15. Remarkable selective constraints on exonic dinucleotide repeats.

    PubMed

    Haasl, Ryan J; Payseur, Bret A

    2014-09-01

    Long dinucleotide repeats found in exons present a substantial mutational hazard: mutations at these loci occur often and generate frameshifts. Here, we provide clear and compelling evidence that exonic dinucleotides experience strong selective constraint. In humans, only 18 exonic dinucleotides have repeat lengths greater than six, which contrasts sharply with the genome-wide distribution of dinucleotides. We genotyped each of these dinucleotides in 200 humans from eight 1000 Genomes Project populations and found a near-absence of polymorphism. More remarkably, divergence data demonstrate that repeat lengths have been conserved across the primate phylogeny in spite of what is likely considerable mutational pressure. Coalescent simulations show that even a very low mutation rate at these loci fails to explain the anomalous patterns of polymorphism and divergence. Our data support two related selective constraints on the evolution of exonic dinucleotides: a short-term intolerance for any change to repeat length and a long-term prevention of increases to repeat length. In general, our results implicate purifying selection as the force that eliminates new, deleterious mutants at exonic dinucleotides. We briefly discuss the evolution of the longest exonic dinucleotide in the human genome--a 10 x CA repeat in fibroblast growth factor receptor-like 1 (FGFRL1)--that should possess a considerably greater mutation rate than any other exonic dinucleotide and therefore generate a large number of deleterious variants. © 2014 The Author(s). Evolution © 2014 The Society for the Study of Evolution.

  16. Movement constraints on interpersonal coordination and communication.

    PubMed

    Tolston, Michael T; Shockley, Kevin; Riley, Michael A; Richardson, Michael J

    2014-10-01

    The present study investigated how constraining movement affects interpersonal coordination and joint cognitive performance. Pairs of participants worked cooperatively to solve picture-puzzle tasks in which they conversed to identify differences between pictures in 3 degree-of-constraint conditions: both participants were free to move their hands (free-free; FF); both participants' hands were restrained (restrained-restrained; RR); and the hands of 1 participant were free while the hands of the other participant were restrained (free-restrained; FR). Eye tracking data were collected, and movement was measured at the waist, hand, and head. Data were analyzed using Cross-Recurrence Quantification Analysis (CRQ). Postural sway coordination, gaze coordination, and task performance were predicted to be highest in FF, followed by RR, and then by FR. Results showed the asymmetric FR condition generally exhibited lesser degrees of coordination than the symmetric Conditions FF and RR, and that the patterning of coordination in the symmetric conditions varied across the measured body segments. These results demonstrate that movement restraints affect not only interpersonal postural coordination, but also joint attention. Additionally, significant positive relationships were found between task performance and total amount of anterior-posterior movement measured at the head, hand and waist; number of utterances; and number of differences pairs found in the puzzles. These findings indicate a relationship between movement and task performance consistent with the hypotheses that both interpersonal coordination and cognitive performance are sensitive to local action constraints.

  17. Collective input/output under memory constraints

    SciTech Connect

    Lu, Yin; Chen, Yong; Zhuang, Yu; Liu, Jialin; Thakur, Rajeev

    2015-01-01

    Compared with current high-performance computing (HPC) systems, exascale systems are expected to have much less memory per node, which can significantly reduce necessary collective input/output (I/O) performance. In this study, we introduce a memory-conscious collective I/O strategy that takes into account memory capacity and bandwidth constraints. The new strategy restricts aggregation data traffic within disjointed subgroups, coordinates I/O accesses in intranode and internode layers, and determines I/O aggregators at run time considering memory consumption among processes. We have prototyped the design and evaluated it with commonly used benchmarks to verify its potential. The evaluation results demonstrate that this strategy holds promise in mitigating the memory pressure, alleviating the contention for memory bandwidth, and improving the I/O performance for projected extreme-scale systems. Given the importance of supporting increasingly data-intensive workloads and projected memory constraints on increasingly larger scale HPC systems, this new memory-conscious collective I/O can have a significant positive impact on scientific discovery productivity.

  18. Observational constraints on assisted k-inflation

    NASA Astrophysics Data System (ADS)

    Ohashi, Junko; Tsujikawa, Shinji

    2011-05-01

    We study observational constraints on the assisted k-inflation models in which multiple scalar fields join an attractor characterized by an effective single field ϕ. This effective single-field system is described by the Lagrangian P=Xg(Y), where X is the kinetic energy of ϕ, λ is a constant, and g is an arbitrary function in terms of Y=Xeλϕ. Our analysis covers a wide variety of k-inflation models such as dilatonic ghost condensate, Dirac-Born-Infeld field, and tachyon, as well as the canonical field with an exponential potential. We place observational bounds on the parameters of each model from the WMAP 7yr data combined with baryon acoustic oscillations and the Hubble constant measurement. Using the observational constraints of the equilateral non-Gaussianity parameter fNLequil, we further restrict the allowed parameter space of dilatonic ghost condensate and Dirac-Born-Infeld models. We extend the analysis to more general models with several different choices of g(Y) and show that the models such as g(Y)=c0+cpYp (p≥3) are excluded by the joint data analysis of the scalar/tensor spectra and primordial non-Gaussianities.

  19. Pressure-temperature-fluid constraints for the Emmaville-Torrington emerald deposit, New South Wales, Australia: Fluid inclusion and stable isotope studies

    NASA Astrophysics Data System (ADS)

    Loughrey, Lara; Marshall, Dan; Jones, Peter; Millsteed, Paul; Main, Arthur

    2012-06-01

    The Emmaville-Torrington emeralds were first discovered in 1890 in quartz veins hosted within a Permian metasedimentary sequence, consisting of meta-siltstones, slates and quartzites intruded by pegmatite and aplite veins from the Moule Granite. The emerald deposit genesis is consistent with a typical granite-related emerald vein system. Emeralds from these veins display colour zonation alternating between emerald and clear beryl. Two fluid inclusion types are identified: three-phase (brine+vapour+halite) and two-phase (vapour+liquid) fluid inclusions. Fluid inclusion studies indicate the emeralds were precipitated from saline fluids ranging from approximately 33 mass percent NaCl equivalent. Formational pressures and temperatures of 350 to 400 °C and approximately 150 to 250 bars were derived from fluid inclusion and petrographic studies that also indicate emerald and beryl precipitation respectively from the liquid and vapour portions of a two-phase (boiling) system. The distinct colour zonations observed in the emerald from these deposits is the first recorded emerald locality which shows evidence of colour variation as a function of boiling. The primary three-phase and primary two-phase FITs are consistent with alternating chromium-rich `striped' colour banding. Alternating emerald zones with colourless beryl are due to chromium and vanadium partitioning in the liquid portion of the boiling system. The chemical variations observed at Emmaville-Torrington are similar to other colour zoned emeralds from other localities worldwide likely precipitated from a boiling system as well.

  20. Pressure-temperature-fluid constraints for the Emmaville-Torrington emerald deposit, New South Wales, Australia: Fluid inclusion and stable isotope studies

    NASA Astrophysics Data System (ADS)

    Loughrey, Lara; Marshall, Dan; Jones, Peter; Millsteed, Paul; Main, Arthur

    2012-06-01

    The Emmaville-Torrington emeralds were first discovered in 1890 in quartz veins hosted within a Permian metasedimentary sequence, consisting of meta-siltstones, slates and quartzites intruded by pegmatite and aplite veins from the Moule Granite. The emerald deposit genesis is consistent with a typical granite-related emerald vein system. Emeralds from these veins display colour zonation alternating between emerald and clear beryl. Two fluid inclusion types are identified: three-phase (brine+vapour+halite) and two-phase (vapour+liquid) fluid inclusions. Fluid inclusion studies indicate the emeralds were precipitated from saline fluids ranging from approximately 33 mass percent NaCl equivalent. Formational pressures and temperatures of 350 to 400 °C and approximately 150 to 250 bars were derived from fluid inclusion and petrographic studies that also indicate emerald and beryl precipitation respectively from the liquid and vapour portions of a two-phase (boiling) system. The distinct colour zonations observed in the emerald from these deposits is the first recorded emerald locality which shows evidence of colour variation as a function of boiling. The primary three-phase and primary two-phase FITs are consistent with alternating chromium-rich `striped' colour banding. Alternating emerald zones with colourless beryl are due to chromium and vanadium partitioning in the liquid portion of the boiling system. The chemical variations observed at Emmaville-Torrington are similar to other colour zoned emeralds from other localities worldwide likely precipitated from a boiling system as well.

  1. New kinematic constraints on the Cantabrian orocline: A paleomagnetic study from the Peñalba and Truchas synclines, NW Spain

    NASA Astrophysics Data System (ADS)

    Fernández-Lozano, Javier; Pastor-Galán, Daniel; Gutiérrez-Alonso, Gabriel; Franco, Piedad

    2016-06-01

    The Cantabrian orocline is a large structure that bends the Variscan orogen of Western Europe in NW Iberia. The extensively studied kinematics of its core, the foreland of the orogen, indicates that the structure is secondary, i.e. acquired after the formation of the orogenic edifice. However, the extent of the Cantabrian orocline away from its core is under debate. In this paper we study the kinematics of the Cantabrian orocline beyond the foreland. We collected and analyzed samples from the northern and central parts of the Truchas syncline, which provides new data within the hinterland of the orogen in NW Iberia. The analysis of 320 samples shows a late Carboniferous remagnetization with an E to NE declination and shallow downward inclinations. These results suggest a counter-clockwise rotation of ~ 60° and peri-equatorial but still southern hemisphere latitude for Iberia during the uppermost Carboniferous-Early Permian. This rotation fits with the expected kinematic evolution of the Truchas syncline if it indeed was part of the Cantabrian orocline.

  2. Constraints on the utility of MnO2 cartridge method for the extraction of radionuclides: A case study using 234Th

    USGS Publications Warehouse

    Baskaran, M.; Swarzenski, P.W.; Biddanda, B.A.

    2009-01-01

    [1] Large volume (102-103 L) seawater samples are routinely processed to investigate the partitioning of particle reactive radionuclides and Ra between solution and size-fractionated suspended particulate matter. One of the most frequently used methods to preconcentrate these nuclides from such large volumes involves extraction onto three filter cartridges (a prefilter for particulate species and two MnO2-coated filters for dissolved species) connected in series. This method assumes that the extraction efficiency is uniform for both MnO2-coated cartridges, that no dissolved species are removed by the prefilter, and that any adsorbed radionuclides are not desorbed from the MnO2-coated cartridges during filtration. In this study, we utilized 234Th-spiked coastal seawater and deionized water to address the removal of dissolved Th onto prefilters and MnO2-coated filter cartridges. Experimental results provide the first data that indicate (1) a small fraction of dissolved Th (<6%) can be removed by the prefilter cartridge; (2) a small fraction of dissolved Th (<5%) retained by the MnO2 surface can also be desorbed, which undermines the assumption of uniform extraction efficiency for Th; and (3) the absolute and relative extraction efficiencies can vary widely. These experiments provide insight on the variability of the extraction efficiency of MnO 2-coated filter cartridges by comparing the relative and absolute efficiencies and recommend the use of a constant efficiency on the combined activity from two filter cartridges connected in series for future studies of dissolved 234Th and other radionuclides in natural waters using sequential filtration/extraction methods. ?? 2009 by the American Geophysical Union.

  3. Paleomagnetic studies on the late Ediacaran - Early Cambrian Puncoviscana and the late Cambrian Campanario formations, NW Argentina: New paleogeographic constraints for the Pampia terrane

    NASA Astrophysics Data System (ADS)

    Franceschinis, Pablo R.; Rapalini, Augusto E.; Escayola, Monica P.; Luppo, Tomás

    2016-10-01

    A magnetofabric and paleomagnetic study was carried out in the Late Ediacaran - Early Cambrian Puncoviscana and the early Late Cambrian Campanario formations, exposed in Santa Victoria Oeste, in northwestern Argentina. Ten sites (93 samples) were located in tuffs and volcanic sills interbedded in the Puncoviscana Formation, one of which had been dated at 537 ± 0.9 Ma. On the other hand, 42 samples were collected at three sites from red to purple sandstones of the Campanario Formation. The analysis of anisotropy of magnetic susceptibility (AMS) allowed to recognize a pre-Andean fabric in both formations indicating that it is previous to the Andean cycle. In the paleomagnetic study reliable magnetic components were isolated in only two sites of the Puncoviscana formation whose virtual geomagnetic poles (VGPs) are close to but do not coincide with the apparent polar wander path of Río de la Plata craton - Gondwana for the late Neoproterozoic - Cambrian. A new paleomagnetic pole (18.2°S, 358.8°W, K: 27.9; A95: 3.9) was computed for the Campanario formation which is close to but does not coincide with those obtained in other locations for this unit and were considered anomalous respect to the expected position in the Gondwana path. The pole presented here is closer to the apparent polar wander path of Gondwana for the Late Cambrian-Early Ordovician suggesting two possible interpretations; the presence of different amounts of Andean tectonic rotations between different sampling locations of the Campanario Formation or the recording of a rapid Pampia dextral displacement along the Rio de la Plata craton margin in Cambrian times.

  4. New constraints on the Pan-African Orogeny in Central Zambia: A structural and geochronological study of the Hook Batholith and the Mwembeshi Zone

    NASA Astrophysics Data System (ADS)

    Naydenov, Kalin V.; Lehmann, Jeremie; Saalmann, Kerstin; Milani, Lorenzo; Kinnaird, Judith A.; Charlesworth, Guy; Frei, Dirk; Rankin, William

    2014-12-01

    In Central Zambia, the Mwembeshi Zone (MwZ) separates two branches of the Pan-African Orogen: the Lufilian Arc and the Zambezi Belt. To the north of the MwZ, the Hook Batholith was emplaced within Neoproterozoic Katangan metasedimentary rocks. Field mapping and structural studies, microstructural observations, interpretation of airborne geophysical images and U-Pb zircon geochronology constrain a new model for the tectonic evolution of this poorly studied part of the orogen. Two temporarily separated and highly oblique orogenic contraction events are defined. D1 is characterised by a regional low-metamorphic grade E-W shortening that produced strain partitioning between N-S trending pure-shear-dominated and NW trending sinistral simple-shear dominated domains. The emplacement of the batholith between ca. 550 and 533 Ma (U-Pb zircon ages) is syn-tectonic to D1. The D2 N-S shortening event was active after ca. 530, which is indicated by the age of the newly dated, deformed molasse of the Hook Batholith. During D2, the MwZ developed as an E- to ENE-striking zone of pure-shear dominated deformation that localised to the south and within the already exhumed Hook Batholith. At the scale of the Pan-African Orogen in Southern Africa, the D1 is considered to be a far field expression of the E-W collision event in the Mozambique Belt. The following Early Cambrian D2 event corresponds to the high angle collision between the Congo and Kalahari Cratons and the stitching of the Lufilian and Zambezi belts along the MwZ. Therefore, in the Hook area, the MwZ cannot be regarded as a continental-scale wrench structure as widely discussed in the literature. The tectonic events in Central Zambia suggest that the amalgamation of Gondwana was accompanied by suturing along highly oblique orogenic belts during plate reorganization at around 530 Ma.

  5. Static single-arm force generation with kinematic constraints.

    PubMed

    Pan, Peng; Peshkin, Michael A; Colgate, J Edward; Lynch, Kevin M

    2005-05-01

    Smooth, frictionless, kinematic constraints on the motion of a grasped object reduce the motion freedoms at the hand, but add force freedoms, that is, force directions that do not affect the motion of the object. We are studying how subjects make use of these force freedoms in static and dynamic manipulation tasks. In this study, subjects were asked to use their right hand to hold stationary a manipulandum being pulled with constant force along a low-friction linear rail. To accomplish this task, subjects had to apply an equal and opposite force along the rail, but subjects were free to apply a force against the constraint, orthogonal to the pulling force. Although constraint forces increase the magnitude of the total force vector at the hand and have no effect on the task, we found that subjects applied significant constraint forces in a consistent manner dependent on the arm and constraint configurations. We show that these results can be interpreted in terms of an objective function describing how subjects choose a particular hand force from an infinite set of hand forces that accomplish the task. Without assuming any particular form for the objective function, the data show that its level sets are convex and scale invariant (i.e., the level set shapes are independent of the hand-force magnitude). We derive the level sets, or "isocost" contours, of subjects' objective functions directly from the experimental data.

  6. Causality constraints in conformal field theory

    SciTech Connect

    Hartman, Thomas; Jain, Sachin; Kundu, Sandipan

    2016-05-17

    Causality places nontrivial constraints on QFT in Lorentzian signature, for example fixing the signs of certain terms in the low energy Lagrangian. In d dimensional conformal field theory, we show how such constraints are encoded in crossing symmetry of Euclidean correlators, and derive analogous constraints directly from the conformal bootstrap (analytically). The bootstrap setup is a Lorentzian four-point function corresponding to propagation through a shockwave. Crossing symmetry fixes the signs of certain log terms that appear in the conformal block expansion, which constrains the interactions of low-lying operators. As an application, we use the bootstrap to rederive the well known sign constraint on the (Φ)4 coupling in effective field theory, from a dual CFT. We also find constraints on theories with higher spin conserved currents. As a result, our analysis is restricted to scalar correlators, but we argue that similar methods should also impose nontrivial constraints on the interactions of spinning operators

  7. Causality constraints in conformal field theory

    NASA Astrophysics Data System (ADS)

    Hartman, Thomas; Jain, Sachin; Kundu, Sandipan

    2016-05-01

    Causality places nontrivial constraints on QFT in Lorentzian signature, for example fixing the signs of certain terms in the low energy Lagrangian. In d dimensional conformal field theory, we show how such constraints are encoded in crossing symmetry of Euclidean correlators, and derive analogous constraints directly from the conformal bootstrap (analytically). The bootstrap setup is a Lorentzian four-point function corresponding to propagation through a shockwave. Crossing symmetry fixes the signs of certain log terms that appear in the conformal block expansion, which constrains the interactions of low-lying operators. As an application, we use the bootstrap to rederive the well known sign constraint on the (∂ ϕ)4 coupling in effective field theory, from a dual CFT. We also find constraints on theories with higher spin conserved currents. Our analysis is restricted to scalar correlators, but we argue that similar methods should also impose nontrivial constraints on the interactions of spinning operators.

  8. Constraint-based interactive assembly planning

    SciTech Connect

    Jones, R.E.; Wilson, R.H.; Calton, T.L.

    1997-03-01

    The constraints on assembly plans vary depending on the product, assembly facility, assembly volume, and many other factors. This paper describes the principles and implementation of a framework that supports a wide variety of user-specified constraints for interactive assembly planning. Constraints from many sources can be expressed on a sequencing level, specifying orders and conditions on part mating operations in a number of ways. All constraints are implemented as filters that either accept or reject assembly operations proposed by the planner. For efficiency, some constraints are supplemented with special-purpose modifications to the planner`s algorithms. Replanning is fast enough to enable a natural plan-view-constrain-replan cycle that aids in constraint discovery and documentation. We describe an implementation of the framework in a computer-aided assembly planning system and experiments applying the system to several complex assemblies. 12 refs., 2 figs., 3 tabs.

  9. Adaptive laser link reconfiguration using constraint propagation

    NASA Technical Reports Server (NTRS)

    Crone, M. S.; Julich, P. M.; Cook, L. M.

    1993-01-01

    This paper describes Harris AI research performed on the Adaptive Link Reconfiguration (ALR) study for Rome Lab, and focuses on the application of constraint propagation to the problem of link reconfiguration for the proposed space based Strategic Defense System (SDS) Brilliant Pebbles (BP) communications system. According to the concept of operations at the time of the study, laser communications will exist between BP's and to ground entry points. Long-term links typical of RF transmission will not exist. This study addressed an initial implementation of BP's based on the Global Protection Against Limited Strikes (GPALS) SDI mission. The number of satellites and rings studied was representative of this problem. An orbital dynamics program was used to generate line-of-site data for the modeled architecture. This was input into a discrete event simulation implemented in the Harris developed COnstraint Propagation Expert System (COPES) Shell, developed initially on the Rome Lab BM/C3 study. Using a model of the network and several heuristics, the COPES shell was used to develop the Heuristic Adaptive Link Ordering (HALO) Algorithm to rank and order potential laser links according to probability of communication. A reduced set of links based on this ranking would then be used by a routing algorithm to select the next hop. This paper includes an overview of Constraint Propagation as an Artificial Intelligence technique and its embodiment in the COPES shell. It describes the design and implementation of both the simulation of the GPALS BP network and the HALO algorithm in COPES. This is described using a 59 Data Flow Diagram, State Transition Diagrams, and Structured English PDL. It describes a laser communications model and the heuristics involved in rank-ordering the potential communication links. The generation of simulation data is described along with its interface via COPES to the Harris developed View Net graphical tool for visual analysis of communications

  10. The timing of eclogite facies metamorphism and migmatization in the Orlica–Śnieżnik complex, Bohemian Massif: Constraints from a multimethod geochronological study

    USGS Publications Warehouse

    Brocker, M.; Klemd, R.; Cosca, M.; Brock, W.; Larionov, A.N.; Rodionov, N.

    2009-01-01

    The Orlica–Śnieżnik complex (OSC) is a key geological element of the eastern Variscides and mainly consists of amphibolite facies orthogneisses and metasedimentary rocks. Sporadic occurrences of eclogites and granulites record high-pressure (HP) to ultrahigh-pressure (UHP) metamorphic conditions. A multimethod geochronological approach (40Ar–39Ar, Rb–Sr, Sm–Nd, U–Pb) has been used to gain further insights into the polymetamorphic evolution of eclogites and associated country rocks. Special attention was given to the unresolved significance of a 370- to 360 Ma age group that was repeatedly described in previous studies. Efforts to verify the accuracy of c.370 Ma K–Ar phengite and biotite dates reported for an eclogite and associated country-rock gneiss from the location Nowa Wieś suggest that these dates are meaningless, due to contamination with extraneous Ar. Extraneous Ar is also considered to be responsible for a significantly older 40Ar–39Ar phengite date of c. 455 Ma for an eclogite from the location Wojtowka. Attempts to further substantiate the importance of 370–360 Ma zircon dates as an indicator for a melt-forming high-temperature (HT) episode did not provide evidence in support of anatectic processes at this time. Instead, SHRIMP U–Pb zircon dating of leucosomes and leucocratic veins within both orthogneisses and (U)HP granulites revealed two age populations (490–450 and 345–330 Ma respectively) that correspond to protolith ages of the magmatic precursors and late Variscan anatexis. The results of this study further underline the importance of Late Carboniferous metamorphic processes for the evolution of the OSC that comprise the waning stages of HP metamorphism and lower pressure HT overprinting with partial melting. Eclogites and their country rocks provided no chronometric evidence for an UHP and ultrahigh-temperature episode at 387–360 Ma, as recently suggested for granulites from the OSC, based on Lu–Hf garnet

  11. Constraints on the collision and the pre-collision tectonic configuration between India and Asia from detrital geochronology, thermochronology, and geochemistry studies in the lower Indus basin, Pakistan

    NASA Astrophysics Data System (ADS)

    Zhuang, Guangsheng; Najman, Yani; Guillot, Stephane; Roddaz, Martin; Antoine, Pierre-Olivier; Metais, Gregoire; Carter, Andrew; Marivaux, Laurent; Solangi, Sarfraz

    2016-04-01

    The timing of India-Asia suturing in the Western Himalaya is complex, with the relative timings of collision between the Indian plate and Asian plate with the Kohistan Island arc and a proposed Tethyan Himalayan microcontinent, debated. Here we present an integrated provenance study of geochronology, thermochronology, and geochemistry on the late Cretaceous-Pleistocene sediments from the lower Indus basin on the Indian plate. The detrital zircon U-Pb and fission track data show a reversal in sediment source from a pure Indian signature to increasing inputs from the suture zone and the Asian plate between the middle Paleocene and early Oligocene. The Nd and Sr isotopes narrow down this change to 50 Ma by revealing input of Asian detritus and the establishment of a Nd & Sr isotopic pattern similar to that of the present-day Indus Fan by 50 Ma, with no significant variations up section, contrary to what might be expected if later major collisions had occurred. Our isotopic data indicate that since 50 Ma, Greater India was occupied by a fluvial-deltaic system, analogous to the present-day Indus and named as the Paleo-Indus, which has been transporting Asian detritus southward across the suture zone and Kohistan-Ladakh arc. This suggests that no other ocean basins were located between India and Asia after this time in this region. Our data require that in the west, the India-Asia collision was accomplished by ˜50 Ma.

  12. Stratigraphic and tectonic studies in the central Aquitaine Basin, northern Pyrenees: Constraints on the subsidence and deformation history of a retro-foreland basin

    NASA Astrophysics Data System (ADS)

    Rougier, Géraldine; Ford, Mary; Christophoul, Frédéric; Bader, Anne-Gaëlle

    2016-03-01

    The central North-Pyrenean retrowedge developed on a thinned lithosphere, rich in Keuper evaporites. The behavior of this retro-foreland system is studied using subsidence analyses and a sequentially restored cross-section (120 km, Saint-Gaudens to Castelsarrasin) constrained by new chrono- and lithostratigraphy, surface and subsurface data. During the Late Cretaceous, a first episode of foreland subsidence (E1) produced a narrow marine depocenter (Comminges Basin, 30 km wide), supplied from the east. A synchronous early deformation involved inversion of basement faults and gentle shortening (4.5 km) of the Mesozoic strata above a Keuper decoupling layer. A tectonically quiet period (Q, Paleocene), characterized by a condensed succession (marine and continental), was followed by a second episode of subsidence (E2), basin migration and gentle thick- and thin-skinned shortening (8 km). Continental sedimentation, supplied by the uplifting orogen, first filled a narrow flexural basin (E2, M-L Eocene), then expanded across the Aquitaine Platform (E3, Oligocene-Miocene).

  13. Masculine norms about emotionality and social constraints in young and older adult men with cancer.

    PubMed

    Darabos, Katie; Hoyt, Michael A

    2017-04-01

    Beliefs that men should restrict their display of emotions, or restrictive emotionality, might contribute to adjustment to cancer and this might be sensitive to social receptivity to disclosure. The present research examined relationships of restrictive emotionality, social constraints, and psychological distress in young adults with testicular cancer (N = 171; Study 1) and older men with prostate cancer (N = 66; Study 2). Study 1: positive associations were observed for social constraints and restrictive emotionality with depressive symptoms. Social constraints moderated the relationship, such that high restrictive emotionality was associated with higher depressive symptoms in those with high constraints. Study 2: only social constraints (and not restrictive emotionality) was positively associated with depressive symptoms and cancer-related intrusive thoughts. The social constraints × restrictive emotionality interaction approached significance with depressive symptoms, such with high social constraints low restrictive emotionality was associated with higher depressive symptoms compared to those with less constraints. No significant associations were found for intrusive thoughts in either study. Findings demonstrate unique relationships with psychological distress across the lifespan of men with cancer given perception of constraints and adherence to masculine norms about emotionality.

  14. Effects of Social Constraints on Career Maturity: The Mediating Effect of the Time Perspective

    ERIC Educational Resources Information Center

    Kim, Kyung-Nyun; Oh, Se-Hee

    2013-01-01

    Previous studies have provided mixed results for the effects of social constraints on career maturity. However, there has been growing interest in these effects from the time perspective. Few studies have examined the effects of social constraints on the time perspective which in turn influences career maturity. This study examines the mediating…

  15. Constraints of Implementing Free Secondary Education in Mandera West Sub-County, Mandera County, Kenya

    ERIC Educational Resources Information Center

    Adan, Mohammed Abdi; Orodho, John Aluko

    2015-01-01

    This study sought to find out the constraints of implementing free secondary education (FSE) in secondary schools in Mandera West Sub-County, Mandera County, Kenya. The study is based on the theory of constraints as the researcher examines the factors constraining the achievement of FSE objectives. The study used the survey design. The main…

  16. Effects of Social Constraints on Career Maturity: The Mediating Effect of the Time Perspective

    ERIC Educational Resources Information Center

    Kim, Kyung-Nyun; Oh, Se-Hee

    2013-01-01

    Previous studies have provided mixed results for the effects of social constraints on career maturity. However, there has been growing interest in these effects from the time perspective. Few studies have examined the effects of social constraints on the time perspective which in turn influences career maturity. This study examines the mediating…

  17. Thermodynamic constraints on fluctuation phenomena.

    PubMed

    Maroney, O J E

    2009-12-01

    The relationships among reversible Carnot cycles, the absence of perpetual motion machines, and the existence of a nondecreasing globally unique entropy function form the starting point of many textbook presentations of the foundations of thermodynamics. However, the thermal fluctuation phenomena associated with statistical mechanics has been argued to restrict the domain of validity of this basis of the second law of thermodynamics. Here we demonstrate that fluctuation phenomena can be incorporated into the traditional presentation, extending rather than restricting the domain of validity of the phenomenologically motivated second law. Consistency conditions lead to constraints upon the possible spectrum of thermal fluctuations. In a special case this uniquely selects the Gibbs canonical distribution and more generally incorporates the Tsallis distributions. No particular model of microscopic dynamics need be assumed.

  18. Observational constraints on silent quartessence

    NASA Astrophysics Data System (ADS)

    Amendola, L.; Waga, I.; Finelli, F.

    2005-11-01

    We derive new constraints set by SNIa experiments ('gold' data sample of Riess et al), x-ray galaxy cluster data (Allen et al Chandra measurements of the x-ray gas mass fraction in 26 clusters), large scale structure (Sloan Digital Sky Survey spectrum) and cosmic microwave background (WMAP) on the quartessence Chaplygin model. We consider both adiabatic perturbations and intrinsic non-adiabatic perturbations such that the effective sound speed vanishes (silent Chaplygin). We show that for the adiabatic case only models with equation of state parameter |\\alpha |\\lesssim 10^{-2} are allowed: this means that the allowed models are very close to ΛCDM. In the silent case, however, the results are consistent with observations in a much broader range, -0.3<α<0.7.

  19. Physical constraints for pathogen movement.

    PubMed

    Schwarz, Ulrich S

    2015-10-01

    In this pedagogical review, we discuss the physical constraints that pathogens experience when they move in their host environment. Due to their small size, pathogens are living in a low Reynolds number world dominated by viscosity. For swimming pathogens, the so-called scallop theorem determines which kinds of shape changes can lead to productive motility. For crawling or gliding cells, the main resistance to movement comes from protein friction at the cell-environment interface. Viruses and pathogenic bacteria can also exploit intracellular host processes such as actin polymerization and motor-based transport, if they present the appropriate factors on their surfaces. Similar to cancer cells that also tend to cross various barriers, pathogens often combine several of these strategies in order to increase their motility and therefore their chances to replicate and spread. Copyright © 2015 Elsevier Ltd. All rights reserved.

  20. Atom mapping with constraint programming.

    PubMed

    Mann, Martin; Nahar, Feras; Schnorr, Norah; Backofen, Rolf; Stadler, Peter F; Flamm, Christoph

    2014-01-01

    Chemical reactions are rearrangements of chemical bonds. Each atom in an educt molecule thus appears again in a specific position of one of the reaction products. This bijection between educt and product atoms is not reported by chemical reaction databases, however, so that the "Atom Mapping Problem" of finding this bijection is left as an important computational task for many practical applications in computational chemistry and systems biology. Elementary chemical reactions feature a cyclic imaginary transition state (ITS) that imposes additional restrictions on the bijection between educt and product atoms that are not taken into account by previous approaches. We demonstrate that Constraint Programming is well-suited to solving the Atom Mapping Problem in this setting. The performance of our approach is evaluated for a manually curated subset of chemical reactions from the KEGG database featuring various ITS cycle layouts and reaction mechanisms.

  1. Thermodynamic constraints on fluctuation phenomena

    NASA Astrophysics Data System (ADS)

    Maroney, O. J. E.

    2009-12-01

    The relationships among reversible Carnot cycles, the absence of perpetual motion machines, and the existence of a nondecreasing globally unique entropy function form the starting point of many textbook presentations of the foundations of thermodynamics. However, the thermal fluctuation phenomena associated with statistical mechanics has been argued to restrict the domain of validity of this basis of the second law of thermodynamics. Here we demonstrate that fluctuation phenomena can be incorporated into the traditional presentation, extending rather than restricting the domain of validity of the phenomenologically motivated second law. Consistency conditions lead to constraints upon the possible spectrum of thermal fluctuations. In a special case this uniquely selects the Gibbs canonical distribution and more generally incorporates the Tsallis distributions. No particular model of microscopic dynamics need be assumed.

  2. Simpler way of imposing simplicity constraints

    NASA Astrophysics Data System (ADS)

    Banburski, Andrzej; Chen, Lin-Qing

    2016-11-01

    We investigate a way of imposing simplicity constraints in a holomorphic spin foam model that we recently introduced. Rather than imposing the constraints on the boundary spin network, as is usually done, one can impose the constraints directly on the spin foam propagator. We find that the two approaches have the same leading asymptotic behavior, with differences appearing at higher order. This allows us to obtain a model that greatly simplifies calculations, but still has Regge calculus as its semiclassical limit.

  3. Initial value constraints with tensor matter

    NASA Astrophysics Data System (ADS)

    Jacobson, Ted

    2011-12-01

    In generally covariant metric gravity theories with tensor matter fields, the initial value constraint equations, unlike in general relativity, are in general not just the 0μ components of the metric field equation. This happens because higher derivatives can occur in the matter stress tensor. A universal form for these constraints is derived here from a generalized Bianchi identity that includes matter fields. As an application, the constraints for Einstein-aether theory are found.

  4. Geomagnetic main field modeling using magnetohydrodynamic constraints

    NASA Technical Reports Server (NTRS)

    Estes, R. H.

    1985-01-01

    The influence of physical constraints are investigated which may be approximately satisfied by the Earth's liquid core on models of the geomagnetic main field and its secular variation. A previous report describes the methodology used to incorporate nonlinear equations of constraint into the main field model. The application of that methodology to the GSFC 12/83 field model to test the frozen-flux hypothesis and the usefulness of incorporating magnetohydrodynamic constraints for obtaining improved geomagnetic field models is described.

  5. Cosmological constraints on pseudo-Nambu-Goldstone bosons

    NASA Technical Reports Server (NTRS)

    Frieman, Joshua A.; Jaffe, Andrew H.

    1991-01-01

    Particle physics models with pseudo-Nambu-Goldstone bosons (PNGBs) are characterized by two mass scales: a global spontaneous symmetry breaking scale, f, and a soft (explicit) symmetry breaking scale, Lambda. General model insensitive constraints were studied on this 2-D parameter space arising from the cosmological and astrophysical effects of PNGBs. In particular, constraints were studied arising from vacuum misalignment and thermal production of PNGBs, topological defects, and the cosmological effects of PNGB decay products, as well as astrophysical constraints from stellar PNGB emission. Bounds on the Peccei-Quinn axion scale, 10(exp 10) GeV approx. = or less than f sub pq approx. = or less than 10(exp 10) to 10(exp 12) GeV, emerge as a special case, where the soft breaking scale is fixed at Lambda sub QCD approx. = 100 MeV.

  6. Constraints on the oxidation state of the mantle: An electrochemical and sup 57 Fe Moessbauer study of mantle-derived ilmenites

    SciTech Connect

    Virgo, D.; Luth, R.W. ); Moats, M.A.; Ulmer, G.C. )

    1988-07-01

    Ilmenite samples from four kimberlite localities were studied using electrochemical, Moessbauer spectroscopic, and microprobe analytical techniques in order to infer the oxidation state of their source regions in the mantle. The values of Fe{sup 3+}/{Sigma}Fe calculated from analyses, using three different electron microanalytical instruments assuming ilmenite stoichiometry, are consistently higher than those derived from the Moessbauer data, by as much as 100%. Furthermore, the range in Fe{sup 3+}/{Sigma}Fe calculated using the analyses from different instruments and/or different correction schemes is nearly as large. Thus Fe{sup 3+}/{Sigma}Fe calculated from microprobe analyses should be taken with caution, even if the precision appears high. {sup 57}Fe Moessbauer spectroscopy on the electrochemical experiment run products demonstrates that Fe{sup 3+}/{Sigma}Fe is significantly lower than it is for the natural C-bearing ilmenites. In contrast, the ilmenite that lacked C did not change Fe{sup 3+}/{Sigma}Fe during the electrochemical experiment. Examination of the reduced samples with SEM established that the natural, single-phase ilmenites exsolved during the electrochemical experiment to form ilmenite{sub ss} + spinel{sub ss}. The initial, reduced trends in the electrochemical experiments for the C-bearing ilmenites are attributed to disequilibrium interactions between the decomposing sample and the evolved gas in the electrochemical cell and do not represent the quenched mantle memory nor the intrinsic f{sub O{sub 2}} of the sample prior to reduction. Furthermore, the oxidized f{sub O{sub 2}} trend is interpreted, for the carbon-bearing samples, are representing the f{sub O{sub 2}} of the ilmenite{sub ss} + spinel{sub ss} assemblage and not the intrinsic f{sub o{sub 2}} of the mantle-derived ilemnite{sub ss}.

  7. The genesis of the Hashitu porphyry molybdenum deposit, Inner Mongolia, NE China: constraints from mineralogical, fluid inclusion, and multiple isotope (H, O, S, Mo, Pb) studies

    NASA Astrophysics Data System (ADS)

    Zhai, Degao; Liu, Jiajun; Tombros, Stylianos; Williams-Jones, Anthony E.

    2017-06-01

    The Hashitu porphyry molybdenum deposit is located in the Great Hinggan Range Cu-Mo-Pb-Zn-Ag polymetallic metallogenic province of NE China, in which the Mo-bearing quartz veins are hosted in approximately coeval granites and porphyries. The deposit contains more than 100 Mt of ore with an average grade of 0.13 wt.% Mo. This well-preserved magmatic-hydrothermal system provides an excellent opportunity to determine the source of the molybdenum, the evolution of the hydrothermal fluids and the controls on molybdenite precipitation in a potentially important but poorly understood metallogenic province. Studies of fluid inclusions hosted in quartz veins demonstrate that the Hashitu hydrothermal system evolved to progressively lower pressure and temperature. Mineralogical and fluid inclusion analyses and physicochemical calculations suggest that molybdenite deposition occurred at a temperature of 285 to 325 °C, a pressure from 80 to 230 bars, a pH from 3.5 to 5.6, and a ∆log fO2 (HM) of -3.0, respectively. Results of multiple isotope (O, H, S, Mo, and Pb) analyses are consistent in indicating a genetic relationship between the ore-forming fluids, metals, and the Mesozoic granitic magmatism (i.e., δ 18OH2O from +1.9 to +9.7‰, δDH2O from -106 to -87‰, δ 34SH2S from +0.3 to +3.9‰, δ 98/95Mo from 0 to +0.37‰, 206Pb/204Pb from 18.2579 to 18.8958, 207Pb/204Pb from 15.5384 to 15.5783, and 208Pb/204Pb from 38.0984 to 42.9744). Molybdenite deposition is interpreted to have occurred from a low-density magmatic-hydrothermal fluid in response to decreases in temperature, pressure, and fO2.

  8. Contamination of MORB by anatexis of magma chamber roof rocks: Constraints from a geochemical study of experimental melts and associated residues

    NASA Astrophysics Data System (ADS)

    France, Lydéric; Koepke, Juergen; MacLeod, Christopher J.; Ildefonse, Benoit; Godard, Marguerite; Deloule, Etienne

    2014-08-01

    Mid-ocean ridge basalts (MORBs) are the most abundant magmas produced on Earth. They are widely studied to infer mantle compositions and melting processes. However, MORB liquids are also the complex end-product of a variety of intra-crustal processes such as partial or fractional crystallization, melt-rock interaction, and contamination. Deciphering the relative contribution of these different processes is of first-order importance. Contamination at ocean crustal levels is likely, and may occur at magma chamber margins where fresh magmas can interact with previously hydrothermally altered rocks. Characterizing the composition of this crustal contaminant component is critical if we are to understand the relative importance of each component in the resulting MORB liquid. Here we present the results of experiments designed to reproduce the processes occurring at oceanic magma chamber roofs, where crustal contamination should be most extensive, by melting a representative sample of the sheeted dike complex. Anatectic melts thus produced are likely to represent the principal crustal contaminant in MORB. These melts were characterized for major and trace elements, showing B, Zr, Hf, and U enrichment, and Sr, Ti, and V depletion relative to original MORB liquids. In comparison to the starting material, relative element fractionations are observed in the anatectic melts, with enrichments of: U relative to Ba, Nb, and Th; LREE and MREE relative to Sr; and Zr-Hf relative to LREE. Bulk partition coefficients for element partitioning during magma chamber roof anatexis are derived and proposed as valuable tools for tracking MORB contamination. Comparison with natural samples from the East Pacific Rise and the Oman ophiolite shows that anatectic melts can crystallize in situ to form oceanic plagiogranite intrusions, and that residual assemblages associated with the hydrous partial melting stage are represented by hornfelsic dikes and enclaves (also named granoblastic basalts

  9. An integrated analysis of micro- and macro-habitat features as a tool to detect weather-driven constraints: A case study with cavity nesters.

    PubMed

    Campobello, D; Lindström, J; Di Maggio, R; Sarà, M

    2017-01-01

    The effects of climate change on animal populations may be shaped by habitat characteristics at both micro- and macro-habitat level, however, empirical studies integrating these two scales of observation are lacking. As analyses of the effects of climate change commonly rely on data from a much larger scale than the microhabitat level organisms are affected at, this mismatch risks hampering progress in developing understanding of the details of the ecological and evolutionary responses of organisms and, ultimately, effective actions to preserve their populations. Cavity nesters, often with a conservation status of concern, are an ideal model because the cavity is a microenvironment potentially different from the macroenvironment but nonetheless inevitably interacting with it. The lesser kestrel (Falco naumanni) is a cavity nester which was until recently classified by as Vulnerable species. Since 2004, for nine years, we collected detailed biotic and abiotic data at both micro- and macro-scales of observation in a kestrel population breeding in the Gela Plain (Italy), a Mediterranean area where high temperatures may reach lethal values for the nest content. We show that macroclimatic features needed to be integrated with both abiotic and biotic factors recorded at a microscale before reliably predicting nest temperatures. Among the nest types used by lesser kestrels, we detected a preferential occupation of the cooler nest types, roof tiles, by early breeders whereas, paradoxically, late breeders nesting with hotter temperatures occupied the overheated nest holes. Not consistent with such a suggested nest selection, the coolest nest type did not host a higher reproductive success than the overheated nests. We discussed our findings in the light of cavity temperatures and nest types deployed within conservation actions assessed by integrating selected factors at different observation scales.

  10. An integrated analysis of micro- and macro-habitat features as a tool to detect weather-driven constraints: A case study with cavity nesters

    PubMed Central

    Campobello, D.; Lindström, J.; Di Maggio, R.; Sarà, M.

    2017-01-01

    The effects of climate change on animal populations may be shaped by habitat characteristics at both micro- and macro-habitat level, however, empirical studies integrating these two scales of observation are lacking. As analyses of the effects of climate change commonly rely on data from a much larger scale than the microhabitat level organisms are affected at, this mismatch risks hampering progress in developing understanding of the details of the ecological and evolutionary responses of organisms and, ultimately, effective actions to preserve their populations. Cavity nesters, often with a conservation status of concern, are an ideal model because the cavity is a microenvironment potentially different from the macroenvironment but nonetheless inevitably interacting with it. The lesser kestrel (Falco naumanni) is a cavity nester which was until recently classified by as Vulnerable species. Since 2004, for nine years, we collected detailed biotic and abiotic data at both micro- and macro-scales of observation in a kestrel population breeding in the Gela Plain (Italy), a Mediterranean area where high temperatures may reach lethal values for the nest content. We show that macroclimatic features needed to be integrated with both abiotic and biotic factors recorded at a microscale before reliably predicting nest temperatures. Among the nest types used by lesser kestrels, we detected a preferential occupation of the cooler nest types, roof tiles, by early breeders whereas, paradoxically, late breeders nesting with hotter temperatures occupied the overheated nest holes. Not consistent with such a suggested nest selection, the coolest nest type did not host a higher reproductive success than the overheated nests. We discussed our findings in the light of cavity temperatures and nest types deployed within conservation actions assessed by integrating selected factors at different observation scales. PMID:28319183

  11. The Impact of Resource Constraints on the Psychological Well-Being of Survivors of Intimate Partner Violence over Time

    ERIC Educational Resources Information Center

    Beeble, Marisa L.; Bybee, Deborah; Sullivan, Cris M.

    2010-01-01

    This study examined the impact of resource constraints on the psychological well-being of survivors of intimate partner violence (IPV), testing whether resource constraints is one mechanism that partially mediates the relationship between IPV and women's well-being. Although within-woman changes in resource constraints did not mediate the…

  12. The Impact of Resource Constraints on the Psychological Well-Being of Survivors of Intimate Partner Violence over Time

    ERIC Educational Resources Information Center

    Beeble, Marisa L.; Bybee, Deborah; Sullivan, Cris M.

    2010-01-01

    This study examined the impact of resource constraints on the psychological well-being of survivors of intimate partner violence (IPV), testing whether resource constraints is one mechanism that partially mediates the relationship between IPV and women's well-being. Although within-woman changes in resource constraints did not mediate the…

  13. Constraints on the collision and the pre-collision tectonic configuration between India and Asia from detrital geochronology, thermochronology, and geochemistry studies in the lower Indus basin, Pakistan

    NASA Astrophysics Data System (ADS)

    Zhuang, Guangsheng; Najman, Yani; Guillot, Stéphane; Roddaz, Martin; Antoine, Pierre-Olivier; Métais, Grégoire; Carter, Andrew; Marivaux, Laurent; Solangi, Sarfraz H.

    2015-12-01

    Knowledge of the timing of India-Asia collision is a fundamental prerequisite for understanding the evolution of the Himalayan-Tibetan orogen and its role in global climate, oceanic chemistry, and ecological evolution. Despite much active research, the basic pre-collision tectonic configuration and the timing of terminal India-Asia suturing remain debated. For example, debates regarding when and how the intervening Kohistan-Ladakh arc was sutured with India and Asia still remain elusive; some models propose the arc collided with Asia at about 100 Ma, with India-Asia collision at ca. 55 Ma, whilst a newer model proposed the arc's collision with India at 50 Ma and subsequently with Asia at 40 Ma. Another example is the recent proposition that an oceanic Greater India Basin separated the Tethyan Himalaya microcontinent from the remaining Indian plate until 20- 25 Ma with the consumption of this oceanic basin marking the final collision at this time. These controversies relate to whether the commonly documented 50 Ma contact represents the terminal India-Asia suturing or the amalgamation between various arcs or microcontinents with India or Asia. Here we present an integrated provenance study of geochronology, thermochronology, and geochemistry on the late Cretaceous-Pleistocene sediments from the lower Indus basin on the Indian plate. The detrital zircon U-Pb and fission track data show a reversal in sediment source from a pure Indian signature to increasing inputs from the suture zone and the Asian plate between the middle Paleocene and early Oligocene. The Nd and Sr isotopes narrow down this change to 50 Ma by revealing input of Asian detritus and the establishment of a Nd & Sr isotopic pattern similar to the present-day Indus Fan by 50 Ma, with no significant variations up section, contrary to what might be expected if later major collisions had occurred. Our isotopic data indicate that Greater India was occupied by a fluvial-deltaic system, analogous to the

  14. HIGH-RESOLUTION STUDY OF THE CLUSTER COMPLEXES IN A LENSED SPIRAL AT REDSHIFT 1.5: CONSTRAINTS ON THE BULGE FORMATION AND DISK EVOLUTION

    SciTech Connect

    Adamo, Angela; Oestlin, G.; Zackrisson, E.; Guaita, L.; Bastian, N.; Livermore, R. C.

    2013-04-01

    We analyze the clump population of the spiral galaxy Sp 1149 at redshift 1.5. Located behind the galaxy cluster MACS J1149.5+2223, Sp 1149 has been significantly magnified allowing us to study the galaxy on physical scales down to {approx}100 pc. The galaxy cluster frame is among the targets of the Cluster Lensing And Supernova survey with Hubble (CLASH), an ongoing Hubble Space Telescope (HST) Multi-Cycle Treasury program. We have used the publicly available multi-band imaging data set to reconstruct the spectral energy distributions of the clumps in Sp 1149, and derive, by means of stellar evolutionary models, their physical properties. We found that 40% of the clumps observed in Sp 1149 are older than 30 Myr and can be as old as 300 Myr. These are also the more massive (luminous) clumps in the galaxy. Among the complexes in the local reference sample, the star-forming knots in luminous blue compact galaxies could be considered progenitor analogs of these long-lived clumps. The remaining 60% of clumps have colors comparable to local cluster complexes, suggesting a similar young age. We observe that the Sp 1149 clumps follow the M{proportional_to}R {sup 2} relation similar to local cluster complexes, suggesting similar formation mechanisms although they may have different initial conditions (e.g., higher gas surface densities). We suggest that the galaxy is experiencing a slow decline in star formation rate and a likely transitional phase toward a more quiescent star formation mode. The older clumps have survived between 6 and 20 dynamical times and are all located at projected distances smaller than 4 kpc from the center. Their current location suggests migration toward the center and the possibility of being the building blocks of the bulge. On the other hand, the dynamical timescale of the younger clumps is significantly shorter, meaning that they are quite close to their birthplace. We show that the clumps of Sp 1149 may account for the expected metal

  15. High-resolution Study of the Cluster Complexes in a Lensed Spiral at Redshift 1.5: Constraints on the Bulge Formation and Disk Evolution

    NASA Astrophysics Data System (ADS)

    Adamo, Angela; Östlin, G.; Bastian, N.; Zackrisson, E.; Livermore, R. C.; Guaita, L.

    2013-04-01

    We analyze the clump population of the spiral galaxy Sp 1149 at redshift 1.5. Located behind the galaxy cluster MACS J1149.5+2223, Sp 1149 has been significantly magnified allowing us to study the galaxy on physical scales down to ~100 pc. The galaxy cluster frame is among the targets of the Cluster Lensing And Supernova survey with Hubble (CLASH), an ongoing Hubble Space Telescope (HST) Multi-Cycle Treasury program. We have used the publicly available multi-band imaging data set to reconstruct the spectral energy distributions of the clumps in Sp 1149, and derive, by means of stellar evolutionary models, their physical properties. We found that 40% of the clumps observed in Sp 1149 are older than 30 Myr and can be as old as 300 Myr. These are also the more massive (luminous) clumps in the galaxy. Among the complexes in the local reference sample, the star-forming knots in luminous blue compact galaxies could be considered progenitor analogs of these long-lived clumps. The remaining 60% of clumps have colors comparable to local cluster complexes, suggesting a similar young age. We observe that the Sp 1149 clumps follow the MvpropR 2 relation similar to local cluster complexes, suggesting similar formation mechanisms although they may have different initial conditions (e.g., higher gas surface densities). We suggest that the galaxy is experiencing a slow decline in star formation rate and a likely transitional phase toward a more quiescent star formation mode. The older clumps have survived between 6 and 20 dynamical times and are all located at projected distances smaller than 4 kpc from the center. Their current location suggests migration toward the center and the possibility of being the building blocks of the bulge. On the other hand, the dynamical timescale of the younger clumps is significantly shorter, meaning that they are quite close to their birthplace. We show that the clumps of Sp 1149 may account for the expected metal-rich globular cluster population

  16. Carbonate cement stratigraphy and timing of diagenesis in a Miocene mixed carbonate-clastic sequence, offshore Sabah, Malaysia: constraints from cathodoluminescence, geochemistry, and isotope studies

    NASA Astrophysics Data System (ADS)

    Yamin Ali, Mohammad

    1995-11-01

    A mixed carbonate-clastic sequence is one of several Miocene hydrocarbon-bearing reservoirs in the northwestern Sabah Basin. This sequence consists of bioclast-rich sandstones interpreted as prograding storm shoal deposits. The sequence contains a complex variety of carbonate nodules. The sequence has undergone nine stages of cementation that completely occluded pores. Each stage represents a distinctive cement texture, precipitating at specific temperatures and burial conditions. The diagenetic evolution began with a syndepositional iron-free marine calcite (Ca1), followed by an early methane-derived dolomite (Do1), bladed calcite (Ca2), blocky, vein-filling Fe-calcites ({Ca3}/{Ca4}, clay mineral-associated dolomite (Do2), Fe-dolomite and ankerite ({Do3}/{Do4}, and late iron-rich calcite (Ca5). Each stage of cement has distinctive Sr2+, Mn2+, Mg2+, Fe2+, Ca2+, and Na+ contents, reflecting changes in the palaeo-porefluid systems with time. The cements are correlatable over the whole study area. Precipitation occurred from very early to late stages of diagenesis at near surface to 2.0 km depths. With progressive burial and temperature increase, oxygen isotope values become strongly negative (stage Ca4: δ13C = -0.5%. PDB, δ18O = -5.7%. PDB). The cements were precipitated at 20-75°C. The source of carbon varies from marine dissolved carbonates to fermentation of organic matter, methane, meteoric waters, and possibly hydrothermal fluids. Strontium isotope dating of Do1 (with δ13C = -32.5%. PDB, δ18O = +2.60%. PDB) and Do2 (δ13C = 3.0%. PDB; δ18O = -2.5%. PDB) dolomites indicates that these dolomitization events took place at 10.5 Ma and 8.9 Ma, respectively, assuming precipitation within a completely open seawater system. The Do1 dolomite was precipitated from a methane-derived brine at the boundary between the Serravallian and Tortonian stages after major uplift, and induced faulting, at a sea-level lowstand. The Do2 dolomite was precipitated during

  17. Fossilization of nanobes studied by transmission electron microscopy and constraints related to their population - recent and late quaternary reefbanks (San Salvador Island, the Bahamas; Heron Island, Australia)

    NASA Astrophysics Data System (ADS)

    Hladil, J.; Gemperle, A.; Carew, J. L.; Bosak, P.; Slavik, L.; Pruner, P.; Charvatova, K.; Mylroie, J. E.; Jell, J. S.

    2003-04-01

    SEM analyses of rocks from Blow Hole Cave and The Gulf sections (San Salvador Island, Bahamas) found that ca 90-95% of peloids (and minor parts of other particles and cements) are substantially rebuilt into tiny corpuscles of ovoid, rotund cylindrical or slightly bent shapes (50-80 × 60-120 nm). About 20-30% of them form short and branched chains. These fabrics resemble `accumulations of ant eggs', have 40-60% fine porosity, correspond to better morpho-definitions of nanobes (cons. by R.L. Folk, 2002), and put a new light on micritization processes. The rocks strongly rebuilt by nanobes negatively correlate with magnetic susceptibility, but slightly contribute to NGR (uranium, gamma-ray spectrometry). In spite of strongly negative correlation to magnetic horizons, the nanobes are also present there, but to a lesser extent. The suspensions with nanobes (extracted by pump from the pores of rocks preserved in glutaraldehyde) exhibit a variety of preservation stages - from amorphous organics to completely fossilized corpuscles (studied by TEM). Early stages of fossilization are characterized by a gradually increasing amount of very fine crystalline inclusions, which are triangular to tetragonal in shape, and 3-15 nm long (mean size ˜ 6 nm). The TEM diffractograms provided data about face-centered cubic structures of B1 type (NaCl-like), with strongest 2nd and 3rd reflections on 0.240 and 0.170 nm and mean lattice parameter of 0.4813 nm. The substance was clearly identified as CaO. The difference to 0.4802 nm (ICDD data for pure CaO) is explained by effects of impurities Sr (+) > Fe, Mn (-). The number of CaO inclusions fluctuates from a few to 5 × 104 / μ {m3}. The CaO nucleation is possible in natural necrotic high-pH low-Eh organic coagulates; but presence of glutaraldehyde can facilitate the process. Other fossilization stages show unstable amorphous to crystalline calcium carbonate, homogeneous aragonite and calcite, and calcite replacing aragonite along sharp

  18. High-Temperature Fractionation of Ni Stable Isotopes Between Metal and Silicates: Constraints from Experimental Study at 800°C and 10 kbar

    NASA Astrophysics Data System (ADS)

    Huh, M. C.; Lazar, C.; Young, E. D.; Manning, C. E.

    2009-12-01

    Shahar et al (2008) demonstrated that the three stable isotope method of Matsuhisa et al (1978) could be applied to measuring Fe isotope fractionation between magnetite and fayalite at upper mantle temperatures. Since Ni has a mass similar to Fe and likewise exists naturally in diverse coordination and bonding environments, it should also show measurable fractionation at high temperatures. We present preliminary measurements of equilibrium nickel isotope fractionation between metal and silicate phases at 800°C and 10 kbar, via MC-ICP-MS analysis of piston cylinder experiments. The chemistry of our experiments was designed using the results of a companion phase equilbria study in the system NiO-SiO2-H2O-O2 (Huh et al 2009). A particularly useful feature of this system is the fO2 of the metal saturation surface, which decreases as silica activity increases (holding other intensive variables constant). At quartz saturation--the maximum silica activity--an invariant point between quartz, metal, and willemseite (Ni-talc) occurs at roughly 5 log fO2 units below the Ni-NiO equilibrium value. Considering this topology, we combined NiO with natural quartz, terrestrial Ni metal and H2O in sealed in Au capsules, and held the experiments at P and T for the desired time. This produced a final assemblage of Ni metal, willemseite (Ni talc), quartz and H2O. The modal abundance of metal increased during the experiment, consistent with the significant drop in oxygen fugacity. Thus, both metal and silicate ingrowth occurred, qualifying our experiments for analysis using the three isotope method. Since quartz is nickel-free, magnetic separation of metal from willemseite+quartz was sufficient to separate both nickel phases for isotopic analysis. Our starting NiO was isotopically shifted off terrestrial mass fractionation (δ61Ni & δ62Ni ≈˜ -28‰) and prepared by oxidizing a mix of commercial and doped metal in nitric acid, followed by precipitation and subsequent dehydration of

  19. Large-Scale Constraint-Based Pattern Mining

    ERIC Educational Resources Information Center

    Zhu, Feida

    2009-01-01

    We studied the problem of constraint-based pattern mining for three different data formats, item-set, sequence and graph, and focused on mining patterns of large sizes. Colossal patterns in each data formats are studied to discover pruning properties that are useful for direct mining of these patterns. For item-set data, we observed robustness of…

  20. Photogeological constraints on lunar and planetary vulcanism, part 1

    NASA Technical Reports Server (NTRS)

    1979-01-01

    Central volcanic constructs were studied as constraints on the thermal evolution and regional tectonics of the Moon and terrestrial planets. The origins of sub-kilometer lunar craters were examined with regards to implications for mare basalt petrogenesis. The morphology, distribution, age, and tectonic setting of the volcanic constructs were studied using Viking Orbiter data.

  1. Computerized Classification Testing under Practical Constraints with a Polytomous Model.

    ERIC Educational Resources Information Center

    Lau, C. Allen; Wang, Tianyou

    A study was conducted to extend the sequential probability ratio testing (SPRT) procedure with the polytomous model under some practical constraints in computerized classification testing (CCT), such as methods to control item exposure rate, and to study the effects of other variables, including item information algorithms, test difficulties, item…

  2. Large-Scale Constraint-Based Pattern Mining

    ERIC Educational Resources Information Center

    Zhu, Feida

    2009-01-01

    We studied the problem of constraint-based pattern mining for three different data formats, item-set, sequence and graph, and focused on mining patterns of large sizes. Colossal patterns in each data formats are studied to discover pruning properties that are useful for direct mining of these patterns. For item-set data, we observed robustness of…

  3. Controlling neural network responsiveness: tradeoffs and constraints

    PubMed Central

    Keren, Hanna; Marom, Shimon

    2014-01-01

    In recent years much effort is invested in means to control neural population responses at the whole brain level, within the context of developing advanced medical applications. The tradeoffs and constraints involved, however, remain elusive due to obvious complications entailed by studying whole brain dynamics. Here, we present effective control of response features (probability and latency) of cortical networks in vitro over many hours, and offer this approach as an experimental toy for studying controllability of neural networks in the wider context. Exercising this approach we show that enforcement of stable high activity rates by means of closed loop control may enhance alteration of underlying global input–output relations and activity dependent dispersion of neuronal pair-wise correlations across the network. PMID:24808860

  4. Experimental Studies of the P-T-H2O Near-Liquidus Phase Relations of Basaltic Andesite From North Sister Volcano, High Oregon Cascades: Constraints on Lower-Crustal Mineral Assemblages

    NASA Astrophysics Data System (ADS)

    Mercer, C. N.; Johnston, A. D.

    2007-05-01

    North Sister Volcano, in the central Oregon High Cascades, is a large, mafic stratovolcano that has erupted a remarkably compositionally limited range of basaltic andesite (53-55 wt.% SiO2) for over 300 ka. Other workers have suggested that these "monotonous" lavas are generated by mantle melts that undergo deep crustal magmatic processes within "deep crustal hot zones" (DCHZ), where the parental melt composition is modified and buffered by reaction with lower-crustal rocks. However, the nature of the lower-arc crust is not well known and a better understanding of the pressure, temperature, composition, and water content of the lower-arc crust is necessary to help constrain these processes. The goal of our study is to elucidate the deep crustal lithology that is involved in the production of mafic arc magmas. We have used hydrous, high pressure experiments to provide P-T-H2O and compositional constraints on the possible lower-crustal mineral assemblages beneath North Sister Volcano. Inverse approach high pressure experiments were conducted using a basaltic andesite from North Sister Volcano, in order to map the water-undersaturated liquidus surface from 5-20 kbar, 1000-1350°C, and 0-15 wt.% H2O. These experiments identify permissible crustal mineral assemblages and compositions with which the North Sister basaltic andesites may have equilibrated in the deep crust before ascent as homogeneous magmas. The liquidus is saturated with plagioclase from 5-15 kbar and 0-5 wt.% H2O, augite from 10-20 kbar at all water contents, garnet above 18 kbar at all water contents, spinel from 5-10 kbar with 10-15 wt.% H2O, and amphibole from 10-20 kbar with 10-15 wt.% H2O. Combining our experimental results with examples of tectonically exposed lower arc crust, trace element geochemistry, geophysical constraints, and melt inclusion volatile contents, we have determined that a mafic granulite at ~12 kbar (~40 km) and 1175°C is the most probable lithology involved in deep crustal

  5. Excitability constraints on voltage-gated sodium channels.

    PubMed

    Angelino, Elaine; Brenner, Michael P

    2007-09-01

    We study how functional constraints bound and shape evolution through an analysis of mammalian voltage-gated sodium channels. The primary function of sodium channels is to allow the propagation of action potentials. Since Hodgkin and Huxley, mathematical models have suggested that sodium channel properties need to be tightly constrained for an action potential to propagate. There are nine mammalian genes encoding voltage-gated sodium channels, many of which are more than approximately 90% identical by sequence. This sequence similarity presumably corresponds to similarity of function, consistent with the idea that these properties must be tightly constrained. However, the multiplicity of genes encoding sodium channels raises the question: why are there so many? We demonstrate that the simplest theoretical constraints bounding sodium channel diversity--the requirements of membrane excitability and the uniqueness of the resting potential--act directly on constraining sodium channel properties. We compare the predicted constraints with functional data on mammalian sodium channel properties collected from the literature, including 172 different sets of measurements from 40 publications, wild-type and mutant, under a variety of conditions. The data from all channel types, including mutants, obeys the excitability constraint; on the other hand, channels expressed in muscle tend to obey the constraint of a unique resting potential, while channels expressed in neuronal tissue do not. The excitability properties alone distinguish the nine sodium channels into four different groups that are consistent with phylogenetic analysis. Our calculations suggest interpretations for the functional differences between these groups.

  6. Linear patterning of mesenchymal condensations is modulated by geometric constraints.

    PubMed

    Klumpers, Darinka D; Mao, Angelo S; Smit, Theo H; Mooney, David J

    2014-06-06

    The development of the vertebral column starts with the formation of a linear array of mesenchymal condensations, forming the blueprint for the eventual alternating pattern of bone and cartilage. Despite growing insight into the molecular mechanisms of morphogenesis, the impact of the physical aspects of the environment is not well understood. We hypothesized that geometric boundary conditions may play a pivotal role in the linear patterning of condensations, as neighbouring tissues provide physical constraints to the cell population. To study the process of condensation and the patterning thereof under tightly controlled geometric constraints, we developed a novel in vitro model that combines micropatterning with the established micromass assay. The spacing and alignment of condensations changed with the width of the cell adhesive patterns, a phenomenon that could not be explained by cell availability alone. Moreover, the extent of chondrogenic commitment was increased on substrates with tighter geometric constraints. When the in vivo pattern of condensations was investigated in the developing vertebral column of chicken embryos, the measurements closely fit into the quantitative relation between geometric constraints and inter-condensation distance found in vitro. Together, these findings suggest a potential role of geometric constraints in skeletal patterning in a cellular process of self-organization.

  7. Airborne Management of Traffic Conflicts in Descent With Arrival Constraints

    NASA Technical Reports Server (NTRS)

    Doble, Nathan A.; Barhydt, Richard; Krishnamurthy, Karthik

    2005-01-01

    NASA is studying far-term air traffic management concepts that may increase operational efficiency through a redistribution of decisionmaking authority among airborne and ground-based elements of the air transportation system. One component of this research, En Route Free Maneuvering, allows trained pilots of equipped autonomous aircraft to assume responsibility for traffic separation. Ground-based air traffic controllers would continue to separate traffic unequipped for autonomous operations and would issue flow management constraints to all aircraft. To evaluate En Route Free Maneuvering operations, a human-in-the-loop experiment was jointly conducted by the NASA Ames and Langley Research Centers. In this experiment, test subject pilots used desktop flight simulators to resolve conflicts in cruise and descent, and to adhere to air traffic flow constraints issued by test subject controllers. Simulators at NASA Langley were equipped with a prototype Autonomous Operations Planner (AOP) flight deck toolset to assist pilots with conflict management and constraint compliance tasks. Results from the experiment are presented, focusing specifically on operations during the initial descent into the terminal area. Airborne conflict resolution performance in descent, conformance to traffic flow management constraints, and the effects of conflicting traffic on constraint conformance are all presented. Subjective data from subject pilots are also presented, showing perceived levels of workload, safety, and acceptability of autonomous arrival operations. Finally, potential AOP functionality enhancements are discussed along with suggestions to improve arrival procedures.

  8. Brain evolution and development: adaptation, allometry and constraint

    PubMed Central

    Barton, Robert A.

    2016-01-01

    Phenotypic traits are products of two processes: evolution and development. But how do these processes combine to produce integrated phenotypes? Comparative studies identify consistent patterns of covariation, or allometries, between brain and body size, and between brain components, indicating the presence of significant constraints limiting independent evolution of separate parts. These constraints are poorly understood, but in principle could be either developmental or functional. The developmental constraints hypothesis suggests that individual components (brain and body size, or individual brain components) tend to evolve together because natural selection operates on relatively simple developmental mechanisms that affect the growth of all parts in a concerted manner. The functional constraints hypothesis suggests that correlated change reflects the action of selection on distributed functional systems connecting the different sub-components, predicting more complex patterns of mosaic change at the level of the functional systems and more complex genetic and developmental mechanisms. These hypotheses are not mutually exclusive but make different predictions. We review recent genetic and neurodevelopmental evidence, concluding that functional rather than developmental constraints are the main cause of the observed patterns. PMID:27629025

  9. Functional constraints on adaptive evolution of protein ubiquitination sites

    PubMed Central

    Lu, Liang; Li, Yang; Liu, Zhongyang; Liang, Fengji; Guo, Feifei; Yang, Shuai; Wang, Dan; He, Yangzhige; Xiong, Jianghui; Li, Dong; He, Fuchu

    2017-01-01

    It is still unclear whether there exist functional constraints on the evolution of protein ubiquitination sites, because most previous studies regarded all protein ubiquitination sites as a whole or only focused on limited structural properties. We tried to clarify the relation between functional constraints and ubiquitination sites evolution. We investigated the evolutionary conservation of human ubiquitination sites in a broad evolutionary scale from G. gorilla to S. pombe, and we found that in organisms originated after the divergence of vertebrate, ubiquitination sites are more conserved than their flanking regions, while the opposite tendency is observed before this divergence time. By grouping the ubiquitination proteins into different functional categories, we confirm that many functional constraints like certain molecular functions, protein tissue expression specificity and protein connectivity in protein-protein interaction network enhance the evolutionary conservation of ubiquitination sites. Furthermore, by analyzing the gains of ubiquitination sites at different divergence time and their functional characters, we validate that the emergences of ubiquitination sites at different evolutionary time were also affected by the uncovered functional constraints. The above results suggest that functional constraints on the adaptive evolution of ubiquitination sites increase the opportunity for ubiquitination to synthetically regulate various cellular and developmental processes during evolution. PMID:28054638

  10. Airborne Management of Traffic Conflicts in Descent With Arrival Constraints

    NASA Technical Reports Server (NTRS)

    Doble, Nathan A.; Barhydt, Richard; Krishnamurthy, Karthik

    2005-01-01

    NASA is studying far-term air traffic management concepts that may increase operational efficiency through a redistribution of decisionmaking authority among airborne and ground-based elements of the air transportation system. One component of this research, En Route Free Maneuvering, allows trained pilots of equipped autonomous aircraft to assume responsibility for traffic separation. Ground-based air traffic controllers would continue to separate traffic unequipped for autonomous operations and would issue flow management constraints to all aircraft. To evaluate En Route Free Maneuvering operations, a human-in-the-loop experiment was jointly conducted by the NASA Ames and Langley Research Centers. In this experiment, test subject pilots used desktop flight simulators to resolve conflicts in cruise and descent, and to adhere to air traffic flow constraints issued by test subject controllers. Simulators at NASA Langley were equipped with a prototype Autonomous Operations Planner (AOP) flight deck toolset to assist pilots with conflict management and constraint compliance tasks. Results from the experiment are presented, focusing specifically on operations during the initial descent into the terminal area. Airborne conflict resolution performance in descent, conformance to traffic flow management constraints, and the effects of conflicting traffic on constraint conformance are all presented. Subjective data from subject pilots are also presented, showing perceived levels of workload, safety, and acceptability of autonomous arrival operations. Finally, potential AOP functionality enhancements are discussed along with suggestions to improve arrival procedures.

  11. Chance-Constrained Guidance With Non-Convex Constraints

    NASA Technical Reports Server (NTRS)

    Ono, Masahiro

    2011-01-01

    Missions to small bodies, such as comets or asteroids, require autonomous guidance for descent to these small bodies. Such guidance is made challenging by uncertainty in the position and velocity of the spacecraft, as well as the uncertainty in the gravitational field around the small body. In addition, the requirement to avoid collision with the asteroid represents a non-convex constraint that means finding the optimal guidance trajectory, in general, is intractable. In this innovation, a new approach is proposed for chance-constrained optimal guidance with non-convex constraints. Chance-constrained guidance takes into account uncertainty so that the probability of collision is below a specified threshold. In this approach, a new bounding method has been developed to obtain a set of decomposed chance constraints that is a sufficient condition of the original chance constraint. The decomposition of the chance constraint enables its efficient evaluation, as well as the application of the branch and bound method. Branch and bound enables non-convex problems to be solved efficiently to global optimality. Considering the problem of finite-horizon robust optimal control of dynamic systems under Gaussian-distributed stochastic uncertainty, with state and control constraints, a discrete-time, continuous-state linear dynamics model is assumed. Gaussian-distributed stochastic uncertainty is a more natural model for exogenous disturbances such as wind gusts and turbulence than the previously studied set-bounded models. However, with stochastic uncertainty, it is often impossible to guarantee that state constraints are satisfied, because there is typically a non-zero probability of having a disturbance that is large enough to push the state out of the feasible region. An effective framework to address robustness with stochastic uncertainty is optimization with chance constraints. These require that the probability of violating the state constraints (i.e., the probability of

  12. Normal gait characteristics under temporal and distance constraints.

    PubMed

    Hirokawa, S

    1989-11-01

    Walking patterns of 53 males and 39 females, all in good health, were studied at slow, free, and fast speeds using a walkway system developed by the author. Three males and three females, also in good health, were then studied under constrained walking conditions such as rhythm constraint, speed coupled with constraint, walking up or down a slope, line stepping constraint, stepping onto a marked square, and starting/stopping of walking. In the first set of experiments, the following results were obtained. When increasing speed, the male had a tendency to increase step length and the female had a tendency to increase cadence. The relationships between the speed and the statistics of gait parameters, i.e. the coefficient of variation and the symmetry were examined. The data in this experiment were also applied to Grieve's gait equations which formulated the relationships between step frequency and speed, or between swing time and cycle time. In the second set of experiments the following results were obtained. Although rhythm constraint (induced by a metronome) resulted in no difference of gait between males and females, a difference did appear in the case of speed coupled with constraint. When walking up and down a slope, the ascent case showed a longer step length and a lower cadence compared with the descent. The idea of functional asymmetry, a supporting function of the left leg and a moving function of the right leg, is well accepted. However, in this study of the effect of line stepping constraints predominant right-left functional differences were found.(ABSTRACT TRUNCATED AT 250 WORDS)

  13. Conformational studies of d-(AAAAATTTTT) sub 2 using constraints from nuclear Overhauser effects and from quantitative analysis of the cross-peak fine structures in two-dimensional H nuclear magnetic resonance spectra

    SciTech Connect

    Celda, B.; Widmer, H.; Leupin, W.; Chazin, W.J.; Denny, W.A.; Wuethrich, K. )

    1989-02-21

    The conformation at the dA-dT junction in k-(AAAAATTTTT){sub 2} was investigated by using a variety of phase-sensitive two-dimensional nuclear magnetic resonance experiments at 500 MHz for detailed studies of the deoxyribose ring puckers. Conformational constraints were collected from two-dimensional nuclear Overhauser enhancement spectra recorded with short mixing times and from quantitative simulations of the cross-peaks in two-dimensional correlated spectra. Overall, the decamer duplex adopts a conformation of the B-DNA type, and for dA{sub 4} and dA{sub 5} the pseudorotation phase angle P is in the standard range 150-180{degree}. The deoxyribose puckers for the other nucleotides deviate significantly from the standard B-DNA structure. Spectrum simulations assuming either static deviations from standard B-DNA or a simple two-state dynamic equilibrium between the C2'-endo and C3'-endo forms of the deoxyribose were used to analyze the experimental data. In agreement with recent papers on related duplexes containing (dA){sub n} tracts, the authors observed prominent nuclear Overhauser effects between adenine-2H and deoxyribose-1'H, which could be largely due to pronounced propeller twisting as observed in the crystal structures of (dA){sub n}-containing compounds.

  14. Study of design constraints on helicopter noise

    NASA Technical Reports Server (NTRS)

    Sternfeld, H., Jr.; Wiedersum, C. W.

    1979-01-01

    A means of estimating the noise generated by a helicopter main rotor using information which is generally available during the preliminary design phase of aircraft development is presented. The method utilizes design charts and tables which do not require an understanding of acoustical theory or computational procedures in order to predict the perceived noise level, a weighted sound pressure level, or C weighted sound pressure level of a single hovering rotor. A method for estimating the effective perceived noise level in forward flight is also included. In order to give the designer an assessment of the relative rotor performance, which may be traded off against noise, an additional chart for estimating the percent of available rotor thrust which must be expended in lifting the rotor and drive system, is included as well as approach for comparing the subjective acceptability of various rotors once the absolute sound pressure levels are predicted.

  15. Application of penalty function method to computation of reachable sets for control systems with state constraints

    NASA Astrophysics Data System (ADS)

    Gusev, M. I.

    2016-10-01

    We study the penalty function type methods for computing the reachable sets of nonlinear control systems with state constraints. The state constraints are given by a finite system of smooth inequalities. The proposed methods are based on removing the state constraints by replacing the original system with an auxiliary system without constraints. This auxiliary system is obtained by modifying the set of velocities of the original system around the boundary of constraints. The right-hand side of the system depends on a penalty parameter. We prove that the reachable sets of the auxiliary system approximate in the Hausdorff metric the reachable set of the original system with state constraints as the penalty parameter tends to zero (infinity) and give the estimates of the rate of convergence. The numerical algorithms for computing the reachable sets, based on Pontryagin's maximum principle, are also considered.

  16. Stakeholders' influence on the importance of users' and clients' information and constraints during website design.

    PubMed

    Chevalier, Aline

    2007-12-01

    The present study aims at determining the role of the stakeholder (via a user vs a client spokesperson) on the importance allocated to information and constraints considered by novice and professional web designers. Analysis showed all designers focused mainly on clients' constraints and information even when they dealt with a user spokesperson: they considered clients' constraints as more important than users' constraints. These results are new with regard to those previously obtained in web design, which showed designers considered prescribed constraints (regardless of the stakeholder to which they are related) as unavaoidable, and the vast majority of others as avoidable if required. Research is required to help web designers to ponder users' and clients' constraints and to assess whether the same patterns of results occur in other design domains.

  17. Registering aerial video images using the projective constraint.

    PubMed

    Jackson, Brian P; Goshtasby, A Ardeshir

    2010-03-01

    To separate object motion from camera motion in an aerial video, consecutive frames are registered at their planar background. Feature points are selected in consecutive frames and those that belong to the background are identified using the projective constraint. Corresponding background feature points are then used to register and align the frames. By aligning video frames at the background and knowing that objects move against the background, a means to detect and track moving objects is provided. Only scenes with planar background are considered in this study. Experimental results show improvement in registration accuracy when using the projective constraint to determine the registration parameters as opposed to finding the registration parameters without the projective constraint.

  18. Combining experimental and cosmological constraints on heavy neutrinos

    NASA Astrophysics Data System (ADS)

    Drewes, Marco; Garbrecht, Björn

    2017-08-01

    We study experimental and cosmological constraints on the extension of the Standard Model by three right handed neutrinos with masses between those of the pion and W boson. We combine for the first time direct, indirect and cosmological constraints in this mass range. This includes experimental constraints from neutrino oscillation data, neutrinoless double β decay, electroweak precision data, lepton universality, searches for rare lepton decays, tests of CKM unitarity and past direct searches at colliders or fixed target experiments. On the cosmological side, big bang nucleosynthesis has the most pronounced impact. Our results can be used to evaluate the discovery potential of searches for heavy neutrinos at LHCb, BELLE II, SHiP, ATLAS, CMS or a future lepton collider.

  19. 'Constraint consistency' at all orders in cosmological perturbation theory

    SciTech Connect

    Nandi, Debottam; Shankaranarayanan, S. E-mail: shanki@iisertvm.ac.in

    2015-08-01

    We study the equivalence of two—order-by-order Einstein's equation and Reduced action—approaches to cosmological perturbation theory at all orders for different models of inflation. We point out a crucial consistency check which we refer to as 'Constraint consistency' condition that needs to be satisfied in order for the two approaches to lead to identical single variable equation of motion. The method we propose here is quick and efficient to check the consistency for any model including modified gravity models. Our analysis points out an important feature which is crucial for inflationary model building i.e., all 'constraint' inconsistent models have higher order Ostrogradsky's instabilities but the reverse is not true. In other words, one can have models with constraint Lapse function and Shift vector, though it may have Ostrogradsky's instabilities. We also obtain single variable equation for non-canonical scalar field in the limit of power-law inflation for the second-order perturbed variables.

  20. Effect of kinematic constraints on multitension string network evolution

    SciTech Connect

    Avgoustidis, Anastasios; Copeland, Edmund J.

    2010-03-15

    We consider the evolution of a network of strings in an expanding Universe, allowing for the formation of junctions between strings of different tensions. By explicitly including, in the velocity-dependent evolution equations for the network, kinematic constraints associated with the formation of Y-shaped string junctions, we show how they lead to scaling solutions in regimes where they would not otherwise be found, thereby extending the range of parameters which lead to scaling. By incorporating these constraints we are able to study their general behavior for networks with cosmic superstring interaction rules, and predict the scaling densities expected by these networks.

  1. Thermodynamics of systems with different geometric constraints and intermolecular correlations.

    PubMed

    Chen, Y; Kilburg, R R; Donohue, M D

    2009-09-17

    Four types of systems with different degrees of geometric constraint and intermolecular correlations were studied to determine the differences in their thermodynamics. The average configurational internal energies of these systems were calculated using Monte Carlo simulations, and the results are compared at the same temperatures and constant average bulk density. From the energy profiles for the four systems, the effects of geometry and intermolecular correlations on the systems' phase behavior are discussed. It was observed that indirect intermolecular correlations, rather than geometric constraints, are the key to achieving a first-order phase transition.

  2. Learning Artificial Phonotactic Constraints: Time Course, Durability, and Relationship to Natural Constraints

    ERIC Educational Resources Information Center

    Taylor, Conrad F.; Houghton, George

    2005-01-01

    G. S. Dell, K. D. Reed, D. R. Adams, and A. S. Meyer (2000) proposed a "breadth-of-constraint" continuum on phoneme errors, using artificial experiment-wide constraints to investigate a putative middle ground between local and language-wide constraints. The authors report 5 experiments that test the idea of the continuum and the location of the…

  3. Learning Artificial Phonotactic Constraints: Time Course, Durability, and Relationship to Natural Constraints

    ERIC Educational Resources Information Center

    Taylor, Conrad F.; Houghton, George

    2005-01-01

    G. S. Dell, K. D. Reed, D. R. Adams, and A. S. Meyer (2000) proposed a "breadth-of-constraint" continuum on phoneme errors, using artificial experiment-wide constraints to investigate a putative middle ground between local and language-wide constraints. The authors report 5 experiments that test the idea of the continuum and the location of the…

  4. Phonological Constraint Induction in a Connectionist Network: Learning OCP-Place Constraints from Data

    ERIC Educational Resources Information Center

    Alderete, John; Tupper, Paul; Frisch, Stefan A.

    2013-01-01

    A significant problem in computational language learning is that of inferring the content of well-formedness constraints from input data. In this article, we approach the constraint induction problem as the gradual adjustment of subsymbolic constraints in a connectionist network. In particular, we develop a multi-layer feed-forward network that…

  5. Phonological Constraint Induction in a Connectionist Network: Learning OCP-Place Constraints from Data

    ERIC Educational Resources Information Center

    Alderete, John; Tupper, Paul; Frisch, Stefan A.

    2013-01-01

    A significant problem in computational language learning is that of inferring the content of well-formedness constraints from input data. In this article, we approach the constraint induction problem as the gradual adjustment of subsymbolic constraints in a connectionist network. In particular, we develop a multi-layer feed-forward network that…

  6. Power System Operations With Water Constraints

    NASA Astrophysics Data System (ADS)

    Qiu, F.; Wang, J.

    2015-12-01

    The interdependency between water and energy, although known for many decades, has not received enough attention until recent events under extreme weather conditions (especially droughts). On one hand, water and several types of energy supplies have become increasingly scarce; the demand on water and energy continues to grow. On the other hand, the climate change has become more and more disruptive (i.e., intensity and frequency of extreme events), causing severe challenges to both systems simultaneously. Water and energy systems have become deeply coupled and challenges from extreme weather events must be addressed in a coordinated way across the two systems.In this work, we will build quantitative models to capture the interactions between water and energy systems. We will incorporate water constraints in power system operations and study the impact of water scarcity on power system resilience.

  7. Particle-physics constraints on multifractal spacetimes

    NASA Astrophysics Data System (ADS)

    Calcagni, Gianluca; Nardelli, Giuseppe; Rodríguez-Fernández, David

    2016-01-01

    We study electroweak interactions in the multiscale theory with q -derivatives, a framework where spacetime has the typical features of a multifractal. In the simplest case with only one characteristic time, length, and energy scale t* , ℓ* , and E* , we consider (i) the muon decay rate and (ii) the Lamb shift in the hydrogen atom, and constrain the corrections to the ordinary results. We obtain the independent absolute upper bounds (i) t*<1 0-13 s and (ii) E*>35 MeV . Under some mild theoretical assumptions, the Lamb shift alone yields the even tighter ranges t*<1 0-27 s , ℓ*<1 0-19 m , and E*>450 GeV . To date, these are the first robust constraints on the scales at which the multifractal features of the geometry can become important in a physical process.

  8. Universal constraints on conformal operator dimensions

    SciTech Connect

    Rychkov, Vyacheslav S.; Vichi, Alessandro

    2009-08-15

    We continue the study of model-independent constraints on the unitary conformal field theories (CFTs) in four dimensions, initiated in [R. Rattazzi, V. S. Rychkov, E. Tonni, and A. Vichi, J. High Energy Phys. 12 (2008) 031]. Our main result is an improved upper bound on the dimension {delta} of the leading scalar operator appearing in the operator product expansion (OPE) of two identical scalars of dimension d: {phi}{sub d}x{phi}{sub d}=1+O{sub {delta}}+.... In the interval 1

  9. Regional magnetic anomaly constraints on continental rifting

    NASA Technical Reports Server (NTRS)

    Vonfrese, R. R. B.; Hinze, W. J.; Olivier, R.; Bentley, C. R.

    1985-01-01

    Radially polarized MAGSAT anomalies of North and South America, Europe, Africa, India, Australia and Antarctica demonstrate remarkably detailed correlation of regional magnetic lithospheric sources across rifted margins when plotted on a reconstruction of Pangea. These major magnetic features apparently preserve their integrity until a superimposed metamorphoric event alters the magnitude and pattern of the anomalies. The longevity of continental scale magnetic anomalies contrasts markedly with that of regional gravity anomalies which tend to reflect predominantly isostatic adjustments associated with neo-tectonism. First observed as a result of NASA's magnetic satellite programs, these anomalies provide new and fundamental constraints on the geologic evolution and dynamics of the continents and oceans. Accordingly, satellite magnetic observations provide a further tool for investigating continental drift to compliment other lines of evidence in paleoclimatology, paleontology, paleomagnetism, and studies of the radiometric ages and geometric fit of the continents.

  10. Geographic Constraints on Social Network Groups

    PubMed Central

    González, Marta C.; Barabási, Albert-László; Christakis, Nicholas A.

    2011-01-01

    Social groups are fundamental building blocks of human societies. While our social interactions have always been constrained by geography, it has been impossible, due to practical difficulties, to evaluate the nature of this restriction on social group structure. We construct a social network of individuals whose most frequent geographical locations are also known. We also classify the individuals into groups according to a community detection algorithm. We study the variation of geographical span for social groups of varying sizes, and explore the relationship between topological positions and geographic positions of their members. We find that small social groups are geographically very tight, but become much more clumped when the group size exceeds about 30 members. Also, we find no correlation between the topological positions and geographic positions of individuals within network communities. These results suggest that spreading processes face distinct structural and spatial constraints. PMID:21483665

  11. f( R) gravity constraints from gravitational waves

    NASA Astrophysics Data System (ADS)

    Vainio, Jaakko; Vilja, Iiro

    2017-08-01

    The recent LIGO observation sparked interest in the field of gravitational wave signals. Besides the gravitational wave observation the LIGO collaboration used the inspiraling black hole pair to constrain the graviton mass. Unlike general relativity, f( R) theories have a characteristic non-zero mass graviton. We apply this constraint on the graviton mass to viable f( R) models in order to find the effects on model parameters. We find it possible to constrain the parameter space with these gravity wave based observations. We consider the popular Hu-Sawicki model as a case study and find an appropriate parameter bracket. The result generalizes to other f( R) theories and can be used to constrain the parameter space.

  12. Participatory evaluation of chicken health and production constraints in Ethiopia

    PubMed Central

    Sambo, Emmanuel; Bettridge, Judy; Dessie, Tadelle; Amare, Alemayehu; Habte, Tadiose; Wigley, Paul; Christley, Robert M.

    2015-01-01

    Chicken production has a major role in the economy of developing countries and backyard production is particularly important to women. Several programmes, in Ethiopia and elsewhere, have attempted to improve chicken production as a means to reduce poverty. A key constraint to chicken production identified by farmers is disease. This study used participatory rural appraisal methods to work with chicken-keepers in order to prioritise chicken diseases, place these within the context of other production constraints, and to explore perceptions of disease risk factors and biosecurity measures. The study, focused on Debre Zeit, Ethiopia, included 71 poultry keepers (41 backyard and 30 semi-intensive chicken producers). Although women played an important role in backyard production systems, semi-intensive farms were more likely to be controlled by men. Participants identified 9 constraints to production: 7 of 8 groups of backyard producers and 15/31 semi-intensive producers ranked diseases as the most important constraint to chicken production. In contrast to previous reports, farmers in both groups had considerable knowledge of diseases and of factors affecting disease risk. Both groups, but particularly semi-intensive producers, highlighted access to feed as a constraint. Many of the challenges faced by both groups were associated with difficulty accessing agricultural and veterinary inputs and expertise. Whilst many of the constraints identified by farmers could be viewed as simply technical issues to be overcome, we believe it is important to recognise the social factors underpinning what are, in reality, relatively modest technical challenges. The low involvement of women in semi-intensive production needs to be recognised by poultry development schemes. Provision needs to be made to allow access to inputs for a wide range of business models, particularly for those, such as women, who have limited access to the capital to allow them to make the jump from backyard to

  13. How Do Severe Constraints Affect the Search Ability of Multiobjective Evolutionary Algorithms in Water Resources?

    NASA Astrophysics Data System (ADS)

    Clarkin, T. J.; Kasprzyk, J. R.; Raseman, W. J.; Herman, J. D.

    2015-12-01

    This study contributes a diagnostic assessment of multiobjective evolutionary algorithm (MOEA) search on a set of water resources problem formulations with different configurations of constraints. Unlike constraints in classical optimization modeling, constraints within MOEA simulation-optimization represent limits on acceptable performance that delineate whether solutions within the search problem are feasible. Constraints are relevant because of the emergent pressures on water resources systems: increasing public awareness of their sustainability, coupled with regulatory pressures on water management agencies. In this study, we test several state-of-the-art MOEAs that utilize restricted tournament selection for constraint handling on varying configurations of water resources planning problems. For example, a problem that has no constraints on performance levels will be compared with a problem with several severe constraints, and a problem with constraints that have less severe values on the constraint thresholds. One such problem, Lower Rio Grande Valley (LRGV) portfolio planning, has been solved with a suite of constraints that ensure high reliability, low cost variability, and acceptable performance in a single year severe drought. But to date, it is unclear whether or not the constraints are negatively affecting MOEAs' ability to solve the problem effectively. Two categories of results are explored. The first category uses control maps of algorithm performance to determine if the algorithm's performance is sensitive to user-defined parameters. The second category uses run-time performance metrics to determine the time required for the algorithm to reach sufficient levels of convergence and diversity on the solution sets. Our work exploring the effect of constraints will better enable practitioners to define MOEA problem formulations for real-world systems, especially when stakeholders are concerned with achieving fixed levels of performance according to one or

  14. Trimodal interpretation of constraints for planning

    NASA Technical Reports Server (NTRS)

    Krieger, David; Brown, Richard

    1987-01-01

    Constraints are used in the CAMPS knowledge based planning system to represent those propositions that must be true for a plan to be acceptable. CAMPS introduces the make-mode for interpreting a constraint. Given an unsatisfied constraint, make evaluation mode suggests planning actions which, if taken, would result in a modified plan in which the constraint in question may be satisfied. These suggested planning actions, termed delta-tuples, are the raw material of intelligent plan repair. They are used both in debugging an almost-right plan and in replanning due to changing situations. Given a defective plan in which some set of constraints are violated, a problem solving strategy selects one or more constraints as a focus of attention. These selected constraints are evaluated in the make-mode to produce delta-tuples. The problem solving strategy then reviews the delta-tuples according to its application and problem-specific criteria to find the most acceptable change in terms of success likelihood and plan disruption. Finally, the problem solving strategy makes the suggested alteration to the plan and then rechecks constraints to find any unexpected consequences.

  15. Linear determining equations for differential constraints

    SciTech Connect

    Kaptsov, O V

    1998-12-31

    A construction of differential constraints compatible with partial differential equations is considered. Certain linear determining equations with parameters are used to find such differential constraints. They generalize the classical determining equations used in the search for admissible Lie operators. As applications of this approach equations of an ideal incompressible fluid and non-linear heat equations are discussed.

  16. CUTTING PLANE METHODS WITHOUT NESTED CONSTRAINT SETS

    DTIC Science & Technology

    General conditions are given for the convergence of a class of cutting -plane algorithms without requiring that the constraint sets for the... cutting -planes include that of Kelley and a generalization of that used by Zoutendisk and Veinott. For algorithms with nested constraint sets, these

  17. The "No Crossing Constraint" in Autosegmental Phonology.

    ERIC Educational Resources Information Center

    Coleman, John; Local, John

    A discussion of autosegmental phonology (AP), a theory of phonological representation that uses graphs rather than strings as the central data structure, considers its principal constraint, the "No Crossing Constraint" (NCC). The NCC is the statement that in a well-formed autosegmental diagram, lines of association may not cross. After…

  18. Domain General Constraints on Statistical Learning

    ERIC Educational Resources Information Center

    Thiessen, Erik D.

    2011-01-01

    All theories of language development suggest that learning is constrained. However, theories differ on whether these constraints arise from language-specific processes or have domain-general origins such as the characteristics of human perception and information processing. The current experiments explored constraints on statistical learning of…

  19. Training Neural Networks with Weight Constraints

    DTIC Science & Technology

    1993-03-01

    Hardware implementation of artificial neural networks imposes a variety of constraints. Finite weight magnitudes exist in both digital and analog...optimizing a network with weight constraints. Comparisons are made to the backpropagation training algorithm for networks with both unconstrained and hard-limited weight magnitudes. Neural networks , Analog, Digital, Stochastic

  20. Constraints, histones, and the 30-nm spiral

    NASA Astrophysics Data System (ADS)

    Zandi, Roya; Rudnick, Joseph

    2001-11-01

    We investigate the mechanical stability of a segment of DNA wrapped around a histone in the nucleosome configuration, under the assumption that the proper model for this packaging arrangement is that of an elastic rod that is free to twist and that writhes subject to mechanical constraints. We find that the number of constraints required to stabilize the nuclesome configuration is determined by the length of the segment, the number of times the DNA wraps around the histone spool, and the specific constraints utilized. While it can be shown that four constraints suffice, in principle, to insure stability of the nucleosome, a proper choice must be made to guarantee the effectiveness of this minimal number. The optimal choice of constraints appears to bear a relation to the existence of a spiral ridge on the surface of the histone octamer. The particular configuration that we investigate is related to the 30-nm spiral, a higher-order organization of DNA in chromatin.

  1. Solar system constraints on disformal gravity theories

    SciTech Connect

    Ip, Hiu Yan; Schmidt, Fabian; Sakstein, Jeremy E-mail: jeremy.sakstein@port.ac.uk

    2015-10-01

    Disformal theories of gravity are scalar-tensor theories where the scalar couples derivatively to matter via the Jordan frame metric. These models have recently attracted interest in the cosmological context since they admit accelerating solutions. We derive the solution for a static isolated mass in generic disformal gravity theories and transform it into the parameterised post-Newtonian form. This allows us to investigate constraints placed on such theories by local tests of gravity. The tightest constraints come from preferred-frame effects due to the motion of the Solar System with respect to the evolving cosmological background field. The constraints we obtain improve upon the previous solar system constraints by two orders of magnitude, and constrain the scale of the disformal coupling for generic models to ℳ ∼> 100 eV. These constraints render all disformal effects irrelevant for cosmology.

  2. Linear predictive control with state variable constraints

    NASA Astrophysics Data System (ADS)

    Bdirina, K.; Djoudi, D.; Lagoun, M.

    2012-11-01

    While linear model predictive control is popular since the 70s of the past century, the 90s have witnessed a steadily increasing attention from control theoretists as well as control practitioners in the area of model predictive control (MPC). The practical interest is driven by the fact that today's processes need to be operated under tighter performance specifications. At the same time more and more constraints, stemming for example from environmental and safety considerations, need to besatisfied. Often these demands can only be met when process constraints are explicitly considered in the controller. Predictive control with constraints appears to be a well suited approach for this kind of problems. In this paper the basic principle of MPC with constraints is reviewed and some of the theoretical, computational, and implementation aspects of MPC are discussed. Furthermore the MPC with constraints was applied to linear example.

  3. Volcanological constraints of Archaean tectonics

    NASA Technical Reports Server (NTRS)

    Thurston, P. C.; Ayres, L. D.

    1986-01-01

    Volcanological and trace element geochemical data can be integrated to place some constraints upon the size, character and evolutionary history of Archean volcanic plumbing, and hence indirectly, Archean tectonics. The earliest volcanism in any greenhouse belt is almost universally tholeitic basalt. Archean mafic magma chambers were usually the site of low pressure fractionation of olivine, plagioclase and later Cpx + or - an oxide phase during evolution of tholeitic liquids. Several models suggest basalt becoming more contaminated by sial with time. Data in the Uchi Subprovince shows early felsic volcanics to have fractionated REE patterns followed by flat REE pattern rhyolites. This is interpreted as initial felsic liquids produced by melting of a garnetiferous mafic source followed by large scale melting of LIL-rich sial. Rare andesites in the Uchi Subprovince are produced by basalt fractionation, direct mantle melts and mixing of basaltic and tonalitic liquids. Composite dikes in the Abitibi Subprovince have a basaltic edge with a chill margin, a rhyolitic interior with no basalt-rhyolite chill margin and partially melted sialic inclusions. Ignimbrites in the Uchi and Abitibi Subprovinces have mafic pumice toward the top. Integration of these data suggest initial mantle-derived basaltic liquids pond in a sialic crust, fractionate and melt sial. The inirial melts low in heavy REE are melts of mafic material, subsequently melting of adjacent sial produces a chamber with a felsic upper part underlain by mafic magma.

  4. Developmental constraints in cave beetles.

    PubMed

    Cieslak, Alexandra; Fresneda, Javier; Ribera, Ignacio

    2014-10-01

    In insects, whilst variations in life cycles are common, the basic patterns typical for particular groups remain generally conserved. One of the more extreme modifications is found in some subterranean beetles of the tribe Leptodirini, in which the number of larval instars is reduced from the ancestral three to two and ultimately one, which is not active and does not feed. We analysed all available data on the duration and size of the different developmental stages and compared them in a phylogenetic context. The total duration of development was found to be strongly conserved, irrespective of geographical location, habitat type, number of instars and feeding behaviour of the larvae, with a single alteration of the developmental pattern in a clade of cave species in southeast France. We also found a strong correlation of the size of the first instar larva with adult size, again regardless of geographical location, ecology and type of life cycle. Both results suggest the presence of deeply conserved constraints in the timing and energy requirements of larval development. Past focus on more apparent changes, such as the number of larval instars, may mask more deeply conserved ontogenetic patterns in developmental timing. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

  5. Developmental constraints in cave beetles

    PubMed Central

    Cieslak, Alexandra; Fresneda, Javier; Ribera, Ignacio

    2014-01-01

    In insects, whilst variations in life cycles are common, the basic patterns typical for particular groups remain generally conserved. One of the more extreme modifications is found in some subterranean beetles of the tribe Leptodirini, in which the number of larval instars is reduced from the ancestral three to two and ultimately one, which is not active and does not feed. We analysed all available data on the duration and size of the different developmental stages and compared them in a phylogenetic context. The total duration of development was found to be strongly conserved, irrespective of geographical location, habitat type, number of instars and feeding behaviour of the larvae, with a single alteration of the developmental pattern in a clade of cave species in southeast France. We also found a strong correlation of the size of the first instar larva with adult size, again regardless of geographical location, ecology and type of life cycle. Both results suggest the presence of deeply conserved constraints in the timing and energy requirements of larval development. Past focus on more apparent changes, such as the number of larval instars, may mask more deeply conserved ontogenetic patterns in developmental timing. PMID:25354919

  6. Hamiltonian constraint in polymer parametrized field theory

    NASA Astrophysics Data System (ADS)

    Laddha, Alok; Varadarajan, Madhavan

    2011-01-01

    Recently, a generally covariant reformulation of two-dimensional flat spacetime free scalar field theory known as parametrized field theory was quantized using loop quantum gravity (LQG) type “polymer” representations. Physical states were constructed, without intermediate regularization structures, by averaging over the group of gauge transformations generated by the constraints, the constraint algebra being a Lie algebra. We consider classically equivalent combinations of these constraints corresponding to a diffeomorphism and a Hamiltonian constraint, which, as in gravity, define a Dirac algebra. Our treatment of the quantum constraints parallels that of LQG and obtains the following results, expected to be of use in the construction of the quantum dynamics of LQG: (i) the (triangulated) Hamiltonian constraint acts only on vertices, its construction involves some of the same ambiguities as in LQG and its action on diffeomorphism invariant states admits a continuum limit, (ii) if the regulating holonomies are in representations tailored to the edge labels of the state, all previously obtained physical states lie in the kernel of the Hamiltonian constraint, (iii) the commutator of two (density weight 1) Hamiltonian constraints as well as the operator correspondent of their classical Poisson bracket converge to zero in the continuum limit defined by diffeomorphism invariant states, and vanish on the Lewandowski-Marolf habitat, (iv) the rescaled density 2 Hamiltonian constraints and their commutator are ill-defined on the Lewandowski-Marolf habitat despite the well-definedness of the operator correspondent of their classical Poisson bracket there, (v) there is a new habitat which supports a nontrivial representation of the Poisson-Lie algebra of density 2 constraints.

  7. Hamiltonian constraint in polymer parametrized field theory

    SciTech Connect

    Laddha, Alok; Varadarajan, Madhavan

    2011-01-15

    Recently, a generally covariant reformulation of two-dimensional flat spacetime free scalar field theory known as parametrized field theory was quantized using loop quantum gravity (LQG) type ''polymer'' representations. Physical states were constructed, without intermediate regularization structures, by averaging over the group of gauge transformations generated by the constraints, the constraint algebra being a Lie algebra. We consider classically equivalent combinations of these constraints corresponding to a diffeomorphism and a Hamiltonian constraint, which, as in gravity, define a Dirac algebra. Our treatment of the quantum constraints parallels that of LQG and obtains the following results, expected to be of use in the construction of the quantum dynamics of LQG: (i) the (triangulated) Hamiltonian constraint acts only on vertices, its construction involves some of the same ambiguities as in LQG and its action on diffeomorphism invariant states admits a continuum limit, (ii) if the regulating holonomies are in representations tailored to the edge labels of the state, all previously obtained physical states lie in the kernel of the Hamiltonian constraint, (iii) the commutator of two (density weight 1) Hamiltonian constraints as well as the operator correspondent of their classical Poisson bracket converge to zero in the continuum limit defined by diffeomorphism invariant states, and vanish on the Lewandowski-Marolf habitat, (iv) the rescaled density 2 Hamiltonian constraints and their commutator are ill-defined on the Lewandowski-Marolf habitat despite the well-definedness of the operator correspondent of their classical Poisson bracket there, (v) there is a new habitat which supports a nontrivial representation of the Poisson-Lie algebra of density 2 constraints.

  8. Stories and Scripts as "Cultural Constraints" on Change in Organisations

    ERIC Educational Resources Information Center

    Amundsen, Oscar

    2014-01-01

    This paper explores narratives and scripts as possible "cultural constraints" on change in an organisation. The empirical basis is a study of employee's perceptions of change processes in a Norwegian finance group. "Narrative" and "script" are key theoretical concepts in the paper, including their potential to grasp…

  9. Constraint-Induced Movement Therapy (CIMT): Pediatric Applications

    ERIC Educational Resources Information Center

    Brady, Kathleen; Garcia, Teressa

    2009-01-01

    The purpose of this article is to describe theoretical and research bases for constraint-induced movement therapy (CIMT), to discuss key features and variations in protocols currently in use with children, and to review the results of studies of efficacy. CIMT has been found to be an effective intervention for increasing functional use of the…

  10. An Examination of Perceived Constraints to Outdoor Recreation

    Treesearch

    G.T. Green; J.M. Bowker; X. Wang; H.K. Cordell; Cassandra Y. Johnson

    2009-01-01

    This study examines whether different social and marginalized groups in American society (minorities, women, rural dwellers, immigrants, low income, less educated) perceive more constraints or barriers to outdoor recreation participation than White middle-class males. Logistic regressions were applied to data from the National Survey on Recreation and the Environment...

  11. Constraint-Induced Movement Therapy (CIMT): Pediatric Applications

    ERIC Educational Resources Information Center

    Brady, Kathleen; Garcia, Teressa

    2009-01-01

    The purpose of this article is to describe theoretical and research bases for constraint-induced movement therapy (CIMT), to discuss key features and variations in protocols currently in use with children, and to review the results of studies of efficacy. CIMT has been found to be an effective intervention for increasing functional use of the…

  12. The Role of Island Constraints in Second Language Sentence Processing

    ERIC Educational Resources Information Center

    Kim, Eunah; Baek, Soondo; Tremblay, Annie

    2015-01-01

    This study investigates whether adult second language learners' online processing of "wh"-dependencies is constrained by island constraints on movement. Proficiency-matched Spanish and Korean learners of English completed a grammaticality judgment task and a stop-making-sense task designed to examine their knowledge of the relative…

  13. The Role of Island Constraints in Second Language Sentence Processing

    ERIC Educational Resources Information Center

    Kim, Eunah; Baek, Soondo; Tremblay, Annie

    2015-01-01

    This study investigates whether adult second language learners' online processing of "wh"-dependencies is constrained by island constraints on movement. Proficiency-matched Spanish and Korean learners of English completed a grammaticality judgment task and a stop-making-sense task designed to examine their knowledge of the relative…

  14. Constraints on nonmetricity from bounds on Lorentz violation

    NASA Astrophysics Data System (ADS)

    Foster, Joshua; Kostelecký, V. Alan; Xu, Rui

    2017-04-01

    Spacetime nonmetricity can be studied experimentally through its couplings to fermions and photons. We use recent high-precision searches for Lorentz violation to deduce first constraints involving the 40 independent nonmetricity components down to levels of order 10-43 GeV .

  15. Acquiring Constraints on Morphosyntactic Variation: Children's Spanish Subject Pronoun Expression

    ERIC Educational Resources Information Center

    Shin, Naomi Lapidus

    2016-01-01

    Constraints on linguistic variation are consistent across adult speakers, yielding probabilistic and systematic patterns. Yet, little is known about the development of such patterns during childhood. This study investigates Spanish subject pronoun expression in naturalistic data from 154 monolingual children in Mexico, divided into four age…

  16. Acquiring Constraints on Morphosyntactic Variation: Children's Spanish Subject Pronoun Expression

    ERIC Educational Resources Information Center

    Shin, Naomi Lapidus

    2016-01-01

    Constraints on linguistic variation are consistent across adult speakers, yielding probabilistic and systematic patterns. Yet, little is known about the development of such patterns during childhood. This study investigates Spanish subject pronoun expression in naturalistic data from 154 monolingual children in Mexico, divided into four age…

  17. Mapping the Developmental Constraints on Working Memory Span Performance

    ERIC Educational Resources Information Center

    Bayliss, Donna M.; Jarrold, Christopher; Baddeley, Alan D.; Gunn, Deborah M.; Leigh, Eleanor

    2004-01-01

    This study investigated the constraints underlying developmental improvements in complex working memory span performance among 120 children of between 6 and 10 years of age. Independent measures of processing efficiency, storage capacity, rehearsal speed, and basic speed of processing were assessed to determine their contribution to age-related…

  18. Constraints and Facilitators for Physical Activity in Family Day Care

    ERIC Educational Resources Information Center

    O'Connor, Justen P.; Temple, Viviene A.

    2005-01-01

    Movement-seeking behaviours should be fostered in young children to maximise their potential to adopt and maintain a physically active lifestyle. This study examined the constraints and facilitators to meaningful movement for children in family day care. The views of key stakeholders (caregivers, parents, and coordination unit staff) were examined…

  19. Tidal constraints on the interior of Venus

    NASA Astrophysics Data System (ADS)

    Dumoulin, Caroline; Tobie, Gabriel; Verhoeven, Olivier; Rosenblatt, Pascal; Rambaux, Nicolas

    2016-10-01

    As a prospective study for a future exploration of Venus, we propose to systematically investigate the signature of the internal structure in the gravity field and the rotation state of Venus, through the determination of the moment of inertia and the tidal Love number.We test various mantle compositions, core size and density as well as temperature profiles representative of different scenarios for formation and evolution of Venus. The mantle density ρ and seismic vP and vS wavespeeds are computed in a consistent manner from given temperature and composition using the Perple X program. This method computes phase equilibria and uses the thermodynamics of mantle minerals developped by Stixrude and Lithgow-Bertelloni (2011).The viscoelastic deformation of the planet interior under the action of periodic tidal forces are computed following the method of Tobie et al. (2005).For a variety of interior models of Venus, the Love number, k2, and the moment of inertia factor are computed following the method described above. The objective is to determine the sensitivity of these synthetic results to the internal structure. These synthetic data are then used to infer the measurement accuracies required on the time-varying gravitational field and the rotation state (precession rate, nutation and length of day variations) to provide useful constraints on the internal structure.We show that a better determination of k2, together with an estimation of the moment of inertia, the radial displacement, and of the time lag, if possible, will refine our knowledge on the present-day interior of Venus (size of the core, mantle temperature, composition and viscosity). Inferring these quantities from a future ex- ploration mission will provide essential constraints on the formation and evolution scenarios of Venus.

  20. Rate-Gyro-Integral Constraint for Ambiguity Resolution in GNSS Attitude Determination Applications

    PubMed Central

    Zhu, Jiancheng; Li, Tao; Wang, Jinling; Hu, Xiaoping; Wu, Meiping

    2013-01-01

    In the field of Global Navigation Satellite System (GNSS) attitude determination, the constraints usually play a critical role in resolving the unknown ambiguities quickly and correctly. Many constraints such as the baseline length, the geometry of multi-baselines and the horizontal attitude angles have been used extensively to improve the performance of ambiguity resolution. In the GNSS/Inertial Navigation System (INS) integrated attitude determination systems using low grade Inertial Measurement Unit (IMU), the initial heading parameters of the vehicle are usually worked out by the GNSS subsystem instead of by the IMU sensors independently. However, when a rotation occurs, the angle at which vehicle has turned within a short time span can be measured accurately by the IMU. This measurement will be treated as a constraint, namely the rate-gyro-integral constraint, which can aid the GNSS ambiguity resolution. We will use this constraint to filter the candidates in the ambiguity search stage. The ambiguity search space shrinks significantly with this constraint imposed during the rotation, thus it is helpful to speeding up the initialization of attitude parameters under dynamic circumstances. This paper will only study the applications of this new constraint to land vehicles. The impacts of measurement errors on the effect of this new constraint will be assessed for different grades of IMU and current average precision level of GNSS receivers. Simulations and experiments in urban areas have demonstrated the validity and efficacy of the new constraint in aiding GNSS attitude determinations. PMID:23793044

  1. Rate-gyro-integral constraint for ambiguity resolution in GNSS attitude determination applications.

    PubMed

    Zhu, Jiancheng; Li, Tao; Wang, Jinling; Hu, Xiaoping; Wu, Meiping

    2013-06-21

    In the field of Global Navigation Satellite System (GNSS) attitude determination, the constraints usually play a critical role in resolving the unknown ambiguities quickly and correctly. Many constraints such as the baseline length, the geometry of multi-baselines and the horizontal attitude angles have been used extensively to improve the performance of ambiguity resolution. In the GNSS/Inertial Navigation System (INS) integrated attitude determination systems using low grade Inertial Measurement Unit (IMU), the initial heading parameters of the vehicle are usually worked out by the GNSS subsystem instead of by the IMU sensors independently. However, when a rotation occurs, the angle at which vehicle has turned within a short time span can be measured accurately by the IMU. This measurement will be treated as a constraint, namely the rate-gyro-integral constraint, which can aid the GNSS ambiguity resolution. We will use this constraint to filter the candidates in the ambiguity search stage. The ambiguity search space shrinks significantly with this constraint imposed during the rotation, thus it is helpful to speeding up the initialization of attitude parameters under dynamic circumstances. This paper will only study the applications of this new constraint to land vehicles. The impacts of measurement errors on the effect of this new constraint will be assessed for different grades of IMU and current average precision level of GNSS receivers. Simulations and experiments in urban areas have demonstrated the validity and efficacy of the new constraint in aiding GNSS attitude determinations.

  2. Natural Constraints to Species Diversification

    PubMed Central

    Lewitus, Eric; Morlon, Hélène

    2016-01-01

    Identifying modes of species diversification is fundamental to our understanding of how biodiversity changes over evolutionary time. Diversification modes are captured in species phylogenies, but characterizing the landscape of diversification has been limited by the analytical tools available for directly comparing phylogenetic trees of groups of organisms. Here, we use a novel, non-parametric approach and 214 family-level phylogenies of vertebrates representing over 500 million years of evolution to identify major diversification modes, to characterize phylogenetic space, and to evaluate the bounds and central tendencies of species diversification. We identify five principal patterns of diversification to which all vertebrate families hold. These patterns, mapped onto multidimensional space, constitute a phylogenetic space with distinct properties. Firstly, phylogenetic space occupies only a portion of all possible tree space, showing family-level phylogenies to be constrained to a limited range of diversification patterns. Secondly, the geometry of phylogenetic space is delimited by quantifiable trade-offs in tree size and the heterogeneity and stem-to-tip distribution of branching events. These trade-offs are indicative of the instability of certain diversification patterns and effectively bound speciation rates (for successful clades) within upper and lower limits. Finally, both the constrained range and geometry of phylogenetic space are established by the differential effects of macroevolutionary processes on patterns of diversification. Given these properties, we show that the average path through phylogenetic space over evolutionary time traverses several diversification stages, each of which is defined by a different principal pattern of diversification and directed by a different macroevolutionary process. The identification of universal patterns and natural constraints to diversification provides a foundation for understanding the deep-time evolution of

  3. Natural Constraints to Species Diversification.

    PubMed

    Lewitus, Eric; Morlon, Hélène

    2016-08-01

    Identifying modes of species diversification is fundamental to our understanding of how biodiversity changes over evolutionary time. Diversification modes are captured in species phylogenies, but characterizing the landscape of diversification has been limited by the analytical tools available for directly comparing phylogenetic trees of groups of organisms. Here, we use a novel, non-parametric approach and 214 family-level phylogenies of vertebrates representing over 500 million years of evolution to identify major diversification modes, to characterize phylogenetic space, and to evaluate the bounds and central tendencies of species diversification. We identify five principal patterns of diversification to which all vertebrate families hold. These patterns, mapped onto multidimensional space, constitute a phylogenetic space with distinct properties. Firstly, phylogenetic space occupies only a portion of all possible tree space, showing family-level phylogenies to be constrained to a limited range of diversification patterns. Secondly, the geometry of phylogenetic space is delimited by quantifiable trade-offs in tree size and the heterogeneity and stem-to-tip distribution of branching events. These trade-offs are indicative of the instability of certain diversification patterns and effectively bound speciation rates (for successful clades) within upper and lower limits. Finally, both the constrained range and geometry of phylogenetic space are established by the differential effects of macroevolutionary processes on patterns of diversification. Given these properties, we show that the average path through phylogenetic space over evolutionary time traverses several diversification stages, each of which is defined by a different principal pattern of diversification and directed by a different macroevolutionary process. The identification of universal patterns and natural constraints to diversification provides a foundation for understanding the deep-time evolution of

  4. Influences of Social Expectations of Gender, Gender Stereotypes, and Situational Constraints on Children's Toy Choices.

    ERIC Educational Resources Information Center

    Raag, Tarja

    1999-01-01

    Two studies calculated the amount of time boys and girls spent playing with toy dishes and tools, examining whether this varied as a function of children's perceptions of social expectations of gender, awareness of gender stereotypes, and situational constraints. Results indicated that situational and perceived social constraints influenced…

  5. Constraints and Challenges on Learning and Construction of Identities at Work

    ERIC Educational Resources Information Center

    Collin, Kaija; Paloniemi, Susanna; Virtanen, Anne; Eteläpelto, Anneli

    2008-01-01

    This paper analyses and discusses different constraints on workplace learning, vocational development and formation of identity. We ask how the learning and development of vocational identities are related to the various learning constraints and restrictions present in the socio-cultural contexts of the workplace. The study utilizes 20 interviews…

  6. Software-Enabled Project Management Techniques and Their Relationship to the Triple Constraints

    ERIC Educational Resources Information Center

    Elleh, Festus U.

    2013-01-01

    This study investigated the relationship between software-enabled project management techniques and the triple constraints (time, cost, and scope). There was the dearth of academic literature that focused on the relationship between software-enabled project management techniques and the triple constraints (time, cost, and scope). Based on the gap…

  7. The Impact of Spatio-Temporal Constraints on Cursive Letter Handwriting in Children

    ERIC Educational Resources Information Center

    Chartrel, Estelle; Vinter, Annie

    2008-01-01

    The study assessed the impact of spatial and temporal constraints on handwriting movements in young children. One hundred children of 5-7 years of age of both genders were given the task of copying isolated cursive letters under four conditions: normal, with temporal, spatial, or spatio-temporal constraints. The results showed that imposing…

  8. Star tracker axis-to-sunlit earth horizon angle constraint evaluations for rendezvous operations

    NASA Technical Reports Server (NTRS)

    Hutchison, W. L.

    1975-01-01

    The results are presented of a study initiated to evaluate the star tracker axis-to-sunlit earth horizon angle constraint with respect to limitations imposed on the passive target rendezvous capability. The data presented include considerations for dispersions and sensor pointing capabilities and generalizations with respect to the uncertainties associated with the angle constraint available in practice.

  9. Software-Enabled Project Management Techniques and Their Relationship to the Triple Constraints

    ERIC Educational Resources Information Center

    Elleh, Festus U.

    2013-01-01

    This study investigated the relationship between software-enabled project management techniques and the triple constraints (time, cost, and scope). There was the dearth of academic literature that focused on the relationship between software-enabled project management techniques and the triple constraints (time, cost, and scope). Based on the gap…

  10. Religious Identity and Cultural Refashioning: Educational Constraints for Migrant Muslim Hui University Students in China

    ERIC Educational Resources Information Center

    Zhao, Dong

    2014-01-01

    This study discusses the educational constraints facing Muslim Hui students and the measures that should be pondered by the Chinese government to address these constraints. Three key research questions are addressed: (1) How does the mainstream Han, Confucian, or the state ideology interact with Hui students' culture? (2) In what ways do ethnic…

  11. Event-Related Potentials Reflecting the Processing of Phonological Constraint Violations

    ERIC Educational Resources Information Center

    Domahs, Ulrike; Kehrein, Wolfgang; Knaus, Johannes; Wiese, Richard; Schlesewsky, Matthias

    2009-01-01

    How are violations of phonological constraints processed in word comprehension? The present article reports the results of an event-related potentials (ERP) study on a phonological constraint of German that disallows identical segments within a syllable or word (CC[subscript i]VC[subscript i]). We examined three types of monosyllabic CCVC words:…

  12. Knowledge of Constraints on Compounding in Children and Adolescents with Williams Syndrome

    ERIC Educational Resources Information Center

    Zukowski, Andrea

    2005-01-01

    This study examines knowledge of a constraint on the form of synthetic noun-noun compounds in a group of 12 children and adolescents with Williams syndrome (WS; age 8-16 years). The constraint blocks regular plurals from appearing inside compounds (e.g., ferrets breeder) while allowing irregular plurals in the same environment (e.g., mice…

  13. Perceived constraints by non-traditional users on the Mt. Baker-Snoqualmie National Forest

    Treesearch

    Elizabeth A. Covelli; Robert C. Burns; Alan Graefe

    2007-01-01

    The purpose of this study was to investigate the constraints that non-traditional users face, along with the negotiation strategies that are employed in order to start, continue, or increase participation in recreation on a national forest. Non-traditional users were defined as respondents who were not Caucasian. Additionally, both constraints and negotiation...

  14. Socioeconomic constraints on the technological choices in rural sewage treatment.

    PubMed

    Gu, Baojing; Fan, Liangcong; Ying, Zechun; Xu, Qingshan; Luo, Weidong; Ge, Ying; Scott, Steffanie; Chang, Jie

    2016-10-01

    Technological innovation is one of the potential engines to mitigate environmental pollution. However, the implementation of new technologies sometimes fails owing to socioeconomic constraints from different stakeholders. Thus, it is essential to analyze constraints of environmental technologies in order to build a pathway for their implementation. In this study, taking three technologies on rural sewage treatment in Hangzhou, China as a case study, i.e., wastewater treatment plant (WTP), constructed wetland (CW), and biogas system, we analyzed how socioeconomic constraints affect the technological choices. Results showed that socioeconomic constraints play a key role through changing the relative opportunity cost of inputs from government as compared to that of residents to deliver the public good-sewage treatment-under different economic levels. Economic level determines the technological choice, and the preferred sewage treatment technologies change from biogas system to CW and further to WTP along with the increase of economic level. Mismatch of technological choice and economic level results in failures of rural sewage treatment, e.g., the CW only work well in moderately developed regions in Hangzhou. This finding expands the environmental Kuznets law by introducing the coproduction theory into analysis (i.e., inputs from both government and residents are essential for the delivery of public goods and services such as good environmental quality). A match between technology and socioeconomic conditions is essential to the environmental governance.

  15. Multiple effects of sentential constraint on word processing

    PubMed Central

    Federmeier, Kara D.; Wlotko, Edward W.; De Ochoa-Dewald, Esmeralda; Kutas, Marta

    2009-01-01

    Behavioral and electrophysiological studies have uncovered different patterns of constraint effects on the processing of words in sentences. Whereas response time measures have indicated a reduced scope of facilitation from strongly constraining contexts, event-related brain potential (ERP) measures have instead revealed enhanced facilitation for semantically related endings in such sentences. Given this disparity, and the concomitant possibility of functionally separable stages of context effects, the current study jointly examined expectancy (cloze probability) and constraint effects on the ERP response to words. Expected and unexpected (but plausible) words completed strongly and weakly constraining sentences; unexpected items were matched for contextual fit across the two levels of constraint and were semantically unrelated to the most expected endings. N400 amplitudes were graded by expectancy but unaffected by constraint and seemed to index the benefit of contextual information. However, a later effect, in the form of increased frontal positivity from 500 to 900 ms post-stimulus-onset, indicated a possible cost associated with the processing of unexpected words in strongly constraining contexts. PMID:16901469

  16. [Environmental efficiency evaluation under carbon emission constraint in Western China].

    PubMed

    Rong, Jian-bo; Yan, Li-jiao; Huang, Shao-rong; Zhang, Ge

    2015-06-01

    This research used the SBM model based on undesirable outputs to measure the static environmental efficiency of Western China under carbon emission constraint from 2000 to 2012. The researchers also utilized the Malmquist index to further analyze the change tendency of environmental efficiency. Additionally, Tobit regression analysis was used to study the factors relevant to environmental efficiency. Practical solutions to improve environmental quality in Western China were put forward. The study showed that in Western China, environmental efficiency with carbon emission constraint was significantly lower than that without carbon emission constraint, and the difference could be described as an inverse U-shaped curve which increased at first and then decreased. Guang-xi and Inner Mongolia, the two provinces met the effective environmental efficiency levels all the time under carbon emission constraint. However, the five provinces of Guizhou, Gansu, Qinghai, Ningxia and Xinjiang did not. Furthermore, Ningxia had the lowest level of environmental efficiency, with a score between 0.281-0.386. Although the environmental efficiency of most provinces was currently at an ineffective level, the environmental efficiency quality was gradually improving at an average speed of 6.6%. Excessive CO2 emission and a large amount of energy consumption were the primary factors causing environmental inefficiency in Western China, and energy intensity had the most negative impact on the environmental efficiency. The increase of import and export trade reduced the environmental efficiency significantly in Western China, while the increase of foreign direct investment had a positive effect on its environmental efficiency.

  17. CONSTRAINT EFFECT IN FRACTURE WHAT IS IT

    SciTech Connect

    Lam, P; Prof. Yuh J. Chao, P

    2008-10-29

    The meaning of the phrase 'constraint effect in fracture' has changed in the past two decades from 'contained plasticity' to a broader description of 'dependence of fracture toughness value on geometry of test specimen or structure'. This paper will first elucidate the fundamental mechanics reasons for the apparent 'constraint effects in fracture', followed by outlining a straightforward approach to overcoming this problem in both brittle (elastic) and ductile (elastic-plastic) fracture. It is concluded by discussing the major difference in constraint effect on fracture event in elastic and elastic-plastic materials.

  18. Astrophysical and cosmological constraints to neutrino properties

    NASA Technical Reports Server (NTRS)

    Kolb, Edward W.; Schramm, David N.; Turner, Michael S.

    1989-01-01

    The astrophysical and cosmological constraints on neutrino properties (masses, lifetimes, numbers of flavors, etc.) are reviewed. The freeze out of neutrinos in the early Universe are discussed and then the cosmological limits on masses for stable neutrinos are derived. The freeze out argument coupled with observational limits is then used to constrain decaying neutrinos as well. The limits to neutrino properties which follow from SN1987A are then reviewed. The constraint from the big bang nucleosynthesis on the number of neutrino flavors is also considered. Astrophysical constraints on neutrino-mixing as well as future observations of relevance to neutrino physics are briefly discussed.

  19. Institutional constraints on alternative water for energy: a guidebook for regional assessments

    SciTech Connect

    Not Available

    1980-11-01

    Basic information is presented about the legal, political, and social constraints faced by energy developers in the acquisition of water from underground, irrigation return flow, municipal waste, and saline sources. It is a guide to those institutional constraints which are general and pronounced enough to be important for regional assessments. First, attention was focused on the acquisition phase of the water use cycle. Second, constraints were analyzed primarily from a regional, rather than state-by-state, perspective. Emphasis was placed generally on the West - particularly the synfuel-rich Rocky Mountain states, the East, and Mid-West, in that order. Alaska and Hawaii were not surveyed. Third, the study focuses on the constraints associated with groundwater, municipal waste, irrigation return flow, and sea water, in that order. The phrase, institutional constraints, as used in the study, means legal, social, economic, and political restrictions, requirements, circumstances, or conditions that must be anticipated or responded to in order to acquire water for energy development. The study focuses primarily on legal constraints and secondarily on political constraints, because they tend to encompass or reflect other forms of institutional constraints.

  20. Planning for environmental constraints on the PJM system

    SciTech Connect

    Not Available

    1994-07-15

    This chapter provides a snapshot of the existing PJM system and identifies the environmental constraints that form the parameters for the regional approaches analyzed in this study. The chapter begins with a description of the PJM system and the costs and emissions levels of the pollutants under study associated with the reference case (the PJM system configured to meet only Clean Air Act Amendment Phase I SO{sub 2} requirements and the March 1994 NO{sub x} requirements affecting Phase I units){sup 3}. Next, the pollution-reduction scenario assumed for the purpose of the study, which covers the period 1995--2010, is described. Finally, the impacts of this pollution reduction scenario -- emissions that would need to be avoided on the reference case PJM system -- are identified. Modeling methods are described alongside the study`s results. Other chapters discuss: environmental constraints, alternate plans to achieve environmental goals, and comparison of alternate plans.

  1. Depinning process of magnetic domain walls in cylindrical nanowires with a chemical constraint

    NASA Astrophysics Data System (ADS)

    Castilla, D.; Maicas, M.; Prieto, J. L.; Proenca, M. P.

    2017-03-01

    In this work we have studied with micromagnetic simulations the pinning process of a magnetic domain wall (DW) travelling in a cylindrical magnetic nanowire with a section where the composition has been altered with respect to the rest of the nanowire (chemical constraint). We have studied the depinning process for a non-magnetic, a paramagnetic and a ferromagnetic constraint and we show that the pinning strength in this type of defect can be tailored by a change of composition. The ferromagnetic chemical constraint is the strongest pinning site but it can stop the DW only when there is a significant reduction of the exchange energy and the saturation magnetization with respect to the rest of the wire. Chemical constraints may constitute a promising alternative to geometrical constraints in some devices such as the race-track memory.

  2. A vowel is a vowel: Generalizing newly-learned phonotactic constraints to new contexts

    PubMed Central

    Chambers, Kyle E.; Onishi, Kristine H.; Fisher, Cynthia

    2010-01-01

    Adults can learn novel phonotactic constraints from brief listening experience. We investigated the representations underlying phonotactic learning by testing generalization to syllables containing new vowels. Adults heard consonant-vowel-consonant (CVC) study syllables in which particular consonants were artificially restricted to onset or coda position (e.g., /f/ is an onset, /s/ is a coda). Subjects were quicker to repeat novel constraint-following (legal) than constraint-violating (illegal) test syllables whether they contained a vowel used in the study syllables (training vowel) or a new (transfer) vowel. This effect emerged regardless of the acoustic similarity between training and transfer vowels. Listeners thus learned and generalized phonotactic constraints that can be characterized as simple first-order constraints on consonant position. Rapid generalization independent of vowel context provides evidence that vowels and consonants are represented independently by processes underlying phonotactic learning. PMID:20438279

  3. Biological constraints do not entail cognitive closure.

    PubMed

    Vlerick, Michael

    2014-12-01

    From the premise that our biology imposes cognitive constraints on our epistemic activities, a series of prominent authors--most notably Fodor, Chomsky and McGinn--have argued that we are cognitively closed to certain aspects and properties of the world. Cognitive constraints, they argue, entail cognitive closure. I argue that this is not the case. More precisely, I detect two unwarranted conflations at the core of arguments deriving closure from constraints. The first is a conflation of what I will refer to as 'representation' and 'object of representation'. The second confuses the cognitive scope of the assisted mind for that of the unassisted mind. Cognitive closure, I conclude, cannot be established from pointing out the (uncontroversial) existence of cognitive constraints. Copyright © 2014 Elsevier Ltd. All rights reserved.

  4. Constraint reasoning in deep biomedical models.

    PubMed

    Cruz, Jorge; Barahona, Pedro

    2005-05-01

    Deep biomedical models are often expressed by means of differential equations. Despite their expressive power, they are difficult to reason about and make decisions, given their non-linearity and the important effects that the uncertainty on data may cause. The objective of this work is to propose a constraint reasoning framework to support safe decisions based on deep biomedical models. The methods used in our approach include the generic constraint propagation techniques for reducing the bounds of uncertainty of the numerical variables complemented with new constraint reasoning techniques that we developed to handle differential equations. The results of our approach are illustrated in biomedical models for the diagnosis of diabetes, tuning of drug design and epidemiology where it was a valuable decision-supporting tool notwithstanding the uncertainty on data. The main conclusion that follows from the results is that, in biomedical decision support, constraint reasoning may be a worthwhile alternative to traditional simulation methods, especially when safe decisions are required.

  5. Constraint-based Attribute and Interval Planning

    NASA Technical Reports Server (NTRS)

    Jonsson, Ari; Frank, Jeremy

    2013-01-01

    In this paper we describe Constraint-based Attribute and Interval Planning (CAIP), a paradigm for representing and reasoning about plans. The paradigm enables the description of planning domains with time, resources, concurrent activities, mutual exclusions among sets of activities, disjunctive preconditions and conditional effects. We provide a theoretical foundation for the paradigm, based on temporal intervals and attributes. We then show how the plans are naturally expressed by networks of constraints, and show that the process of planning maps directly to dynamic constraint reasoning. In addition, we de ne compatibilities, a compact mechanism for describing planning domains. We describe how this framework can incorporate the use of constraint reasoning technology to improve planning. Finally, we describe EUROPA, an implementation of the CAIP framework.

  6. Constraint-based Attribute and Interval Planning

    NASA Technical Reports Server (NTRS)

    Jonsson, Ari; Frank, Jeremy

    2013-01-01

    In this paper we describe Constraint-based Attribute and Interval Planning (CAIP), a paradigm for representing and reasoning about plans. The paradigm enables the description of planning domains with time, resources, concurrent activities, mutual exclusions among sets of activities, disjunctive preconditions and conditional effects. We provide a theoretical foundation for the paradigm, based on temporal intervals and attributes. We then show how the plans are naturally expressed by networks of constraints, and show that the process of planning maps directly to dynamic constraint reasoning. In addition, we de ne compatibilities, a compact mechanism for describing planning domains. We describe how this framework can incorporate the use of constraint reasoning technology to improve planning. Finally, we describe EUROPA, an implementation of the CAIP framework.

  7. Generalized constraint structure for gravitation theory

    SciTech Connect

    Komar, A.

    1983-05-15

    By exploiting the conformal symmetry inherent in the Einstein theory we construct a more general form for the Dirac constraints involving an arbitrary function. This more general form is required if a canonically quantized theory is to accommodate renormalization.

  8. Statistical learning of novel graphotactic constraints in children and adults.

    PubMed

    Samara, Anna; Caravolas, Markéta

    2014-05-01

    The current study explored statistical learning processes in the acquisition of orthographic knowledge in school-aged children and skilled adults. Learning of novel graphotactic constraints on the position and context of letter distributions was induced by means of a two-phase learning task adapted from Onishi, Chambers, and Fisher (Cognition, 83 (2002) B13-B23). Following incidental exposure to pattern-embedding stimuli in Phase 1, participants' learning generalization was tested in Phase 2 with legality judgments about novel conforming/nonconforming word-like strings. Test phase performance was above chance, suggesting that both types of constraints were reliably learned even after relatively brief exposure. As hypothesized, signal detection theory d' analyses confirmed that learning permissible letter positions (d'=0.97) was easier than permissible neighboring letter contexts (d'=0.19). Adults were more accurate than children in all but a strict analysis of the contextual constraints condition. Consistent with the statistical learning perspective in literacy, our results suggest that statistical learning mechanisms contribute to children's and adults' acquisition of knowledge about graphotactic constraints similar to those existing in their orthography. Copyright © 2013 Elsevier Inc. All rights reserved.

  9. Constraints on the density perturbation spectrum from primordial black holes

    NASA Astrophysics Data System (ADS)

    Green, Anne M.; Liddle, Andrew R.

    1997-11-01

    We reexamine the constraints on the density perturbation spectrum, including its spectral index n, from the production of primordial black holes. The standard cosmology, where the Universe is radiation dominated from the end of inflation up until the recent past, was studied by Carr, Gilbert, and Lidsey; we correct two errors in their derivation and find a significantly stronger constraint than they did: n<~1.25 rather than their 1.5. We then consider an alternative cosmology in which a second period of inflation, known as thermal inflation and designed to solve additional relic overdensity problems, occurs at a lower-energy scale than the main inflationary period. In that case, the constraint weakens to n<~1.3, and thermal inflation also leads to a ``missing mass'' range 1018 g<~M<~1026 g in which primordial black holes cannot form. Finally, we discuss the effect of allowing for the expected non-Gaussianity in the density perturbations predicted by Bullock and Primack, which can weaken the constraints further by up to 0.05.

  10. Environmental constraints and call evolution in torrent-dwelling frogs.

    PubMed

    Goutte, Sandra; Dubois, Alain; Howard, Samuel D; Marquez, Rafael; Rowley, Jodi J L; Dehling, J Maximilian; Grandcolas, Philippe; Rongchuan, Xiong; Legendre, Frédéric

    2016-04-01

    Although acoustic signals are important for communication in many taxa, signal propagation is affected by environmental properties. Strong environmental constraints should drive call evolution, favoring signals with greater transmission distance and content integrity in a given calling habitat. Yet, few empirical studies have verified this prediction, possibly due to a shortcoming in habitat characterization, which is often too broad. Here we assess the potential impact of environmental constraints on the evolution of advertisement call in four groups of torrent-dwelling frogs in the family Ranidae. We reconstruct the evolution of calling site preferences, both broadly categorized and at a finer scale, onto a phylogenetic tree for 148 species with five markers (∼3600 bp). We test models of evolution for six call traits for 79 species with regard to the reconstructed history of calling site preferences and estimate their ancestral states. We find that in spite of existing morphological constraints, vocalizations of torrent-dwelling species are most probably constrained by the acoustic specificities of torrent habitats and particularly their high level of ambient noise. We also show that a fine-scale characterization of calling sites allows a better perception of the impact of environmental constraints on call evolution.

  11. Sequential phenotypic constraints on social information use in wild baboons

    PubMed Central

    Carter, Alecia J; Torrents Ticó, Miquel; Cowlishaw, Guy

    2016-01-01

    Social information allows the rapid dissemination of novel information among individuals. However, an individual’s ability to use information is likely to be dependent on phenotypic constraints operating at three successive steps: acquisition, application, and exploitation. We tested this novel framework by quantifying the sequential process of social information use with experimental food patches in wild baboons (Papio ursinus). We identified phenotypic constraints at each step of the information use sequence: peripheral individuals in the proximity network were less likely to acquire and apply social information, while subordinate females were less likely to exploit it successfully. Social bonds and personality also played a limiting role along the sequence. As a result of these constraints, the average individual only acquired and exploited social information on <25% and <5% of occasions. Our study highlights the sequential nature of information use and the fundamental importance of phenotypic constraints on this sequence. DOI: http://dx.doi.org/10.7554/eLife.13125.001 PMID:27067236

  12. Constraints on cosmological parameters in power-law cosmology

    NASA Astrophysics Data System (ADS)

    Rani, Sarita; Altaibayeva, A.; Shahalam, M.; Singh, J. K.; Myrzakulov, R.

    2015-03-01

    In this paper, we examine observational constraints on the power law cosmology; essentially dependent on two parameters H0 (Hubble constant) and q (deceleration parameter). We investigate the constraints on these parameters using the latest 28 points of H(z) data and 580 points of Union2.1 compilation data and, compare the results with the results of ΛCDM . We also forecast constraints using a simulated data set for the future JDEM, supernovae survey. Our studies give better insight into power law cosmology than the earlier done analysis by Kumar [arXiv:1109.6924] indicating it tuning well with Union2.1 compilation data but not with H(z) data. However, the constraints obtained on and i.e. H0 average and q average using the simulated data set for the future JDEM, supernovae survey are found to be inconsistent with the values obtained from the H(z) and Union2.1 compilation data. We also perform the statefinder analysis and find that the power-law cosmological models approach the standard ΛCDM model as q → -1. Finally, we observe that although the power law cosmology explains several prominent features of evolution of the Universe, it fails in details.

  13. Cosmological Constraints from the SDSS maxBCG Cluster Catalog

    SciTech Connect

    Rozo, Eduardo; Wechsler, Risa H.; Rykoff, Eli S.; Annis, James T.; Becker, Matthew R.; Evrard, August E.; Frieman, Joshua A.; Hansen, Sarah M.; Hao, Jia; Johnston, David E.; Koester, Benjamin P.; McKay, Timothy A.; Sheldon, Erin S.; Weinberg, David H.; /CCAPP /Ohio State U.

    2009-08-03

    We use the abundance and weak lensing mass measurements of the SDSS maxBCG cluster catalog to simultaneously constrain cosmology and the richness-mass relation of the clusters. Assuming a flat {Lambda}CDM cosmology, we find {sigma}{sub 8}({Omega}{sub m}/0.25){sup 0.41} = 0.832 {+-} 0.033 after marginalization over all systematics. In common with previous studies, our error budget is dominated by systematic uncertainties, the primary two being the absolute mass scale of the weak lensing masses of the maxBCG clusters, and uncertainty in the scatter of the richness-mass relation. Our constraints are fully consistent with the WMAP five-year data, and in a joint analysis we find {sigma}{sub 8} = 0.807 {+-} 0.020 and {Omega}{sub m} = 0.265 {+-} 0.016, an improvement of nearly a factor of two relative to WMAP5 alone. Our results are also in excellent agreement with and comparable in precision to the latest cosmological constraints from X-ray cluster abundances. The remarkable consistency among these results demonstrates that cluster abundance constraints are not only tight but also robust, and highlight the power of optically-selected cluster samples to produce precision constraints on cosmological parameters.

  14. Constraints on cosmological parameters in power-law cosmology

    SciTech Connect

    Rani, Sarita; Singh, J.K.; Altaibayeva, A.; Myrzakulov, R.; Shahalam, M. E-mail: aziza.bibol@mail.ru E-mail: jainendrrakumar@rediffmail.com

    2015-03-01

    In this paper, we examine observational constraints on the power law cosmology; essentially dependent on two parameters H{sub 0} (Hubble constant) and q (deceleration parameter). We investigate the constraints on these parameters using the latest 28 points of H(z) data and 580 points of Union2.1 compilation data and, compare the results with the results of ΛCDM . We also forecast constraints using a simulated data set for the future JDEM, supernovae survey. Our studies give better insight into power law cosmology than the earlier done analysis by Kumar [arXiv:1109.6924] indicating it tuning well with Union2.1 compilation data but not with H(z) data. However, the constraints obtained on and i.e. H{sub 0} average and q average using the simulated data set for the future JDEM, supernovae survey are found to be inconsistent with the values obtained from the H(z) and Union2.1 compilation data. We also perform the statefinder analysis and find that the power-law cosmological models approach the standard ΛCDM model as q → −1. Finally, we observe that although the power law cosmology explains several prominent features of evolution of the Universe, it fails in details.

  15. Fast Deconvolution with Color Constraints on Gradients

    DTIC Science & Technology

    2013-01-01

    deconvolution approach for color images that combines a sparse regularization cost on the magnitudes of gradients with constraints on their direction in color...Research Office P.O. Box 12211 Research Triangle Park, NC 27709-2211 15. SUBJECT TERMS computer vision, deblurring, spatio-spectral image model Ayan...approach for color images that combines a sparse regularization cost on the magnitudes of gradients with constraints on their direction in color space. We

  16. Program/System Constraints Analysis Report.

    DTIC Science & Technology

    1981-03-01

    Tactical Air Command to comply with the requirements of CDRL no. 8021. The project entailed the design and development of an instru- ctional system for...constraints identified such as weather, range availa- bility, and air space are "hard" and must be accomodated by the training system. Other constraints such... Air Training Command (ATC) d. Fighter Lead-in Training (FLIT) e. General Dynamics, Fort Worth Concurrent with the documentation review and the

  17. Constraints on the morphological evolution of marsupial shoulder girdles.

    PubMed

    Sears, Karen E

    2004-10-01

    Throughout their evolutionary histories, marsupial mammals have been taxonomically and morphologically less diverse than their sister taxa the placentals. Because of this, it has been proposed that the evolution of marsupials has been constrained by the functional requirements of their mode of reproduction. Marsupials give birth after short gestation times to immature neonates that immediately crawl, under the power of their precociously developed shoulder girdles, to the teat where they attach and complete their early development. Using a novel approach incorporating adult and embryological morphological data, this study is the first to both: (1) statistically support adult patterns of morphological divergence consistent with the constraint hypothesis, and (2) identify ontogenetic patterns of morphological change that demonstrate that the constraint was responsible, at least in part, for their formation. As predicted by the marsupial constraint, the shoulder girdles of adult marsupials are less diverse than those of adult placentals, and adult marsupial scapulae are less morphologically diverse than adult marsupial pelves. Furthermore, marsupials that complete an extensive crawl to the teat are restricted to a common pattern of ontogenetic scapular shape change, strongly supporting the hypothesis that the morphological development of the marsupial scapula has been limited evolutionarily by its obligate role in the crawl to the teat. Because this study establishes that ontogenetic and evolutionary morphological change is correlated within mammalian scapulae, it is probable that the marsupial constraint also restricted the morphological divergence of the scapula over evolutionary time by limiting ontogenetic change in the scapula. These findings, coupled with the importance of the shoulder girdle in mammalian locomotor specialization, support the conclusion that the low morphological diversity of marsupial forms over evolutionary time could be directly due to the

  18. Constraints to Implementing the Essential Health Package in Malawi

    PubMed Central

    Mueller, Dirk H.; Lungu, Douglas; Acharya, Arnab; Palmer, Natasha

    2011-01-01

    Increasingly seen as a useful tool of health policy, Essential or Minimal Health Packages direct resources to interventions that aim to address the local burden of disease and be cost-effective. Less attention has been paid to the delivery mechanisms for such interventions. This study aimed to assess the degree to which the Essential Health Package (EHP) in Malawi was available to its population and what health system constraints impeded its full implementation. The first phase of this study comprised a survey of all facilities in three districts including interviews with all managers and clinical staff. In the second and third phase, results were discussed with District Health Management Teams and national level stakeholders, respectively, including representatives of the Ministry of Health, Central Medical Stores, donors and NGOs. The EHP in Malawi is focussing on the local burden of disease; however, key constraints to its successful implementation included a widespread shortage of staff due to vacancies but also caused by frequent trainings and meetings (only 48% of expected man days of clinical staff were available; training and meetings represented 57% of all absences in health centres). Despite the training, the percentage of health workers aware of vital diagnostic and therapeutic approaches to EHP conditions was weak. Another major constraint was shortages of vital drugs at all levels of facilities (e.g. Cotrimoxazole was sufficiently available to treat the average number of patients in only 27% of health centres). Although a few health workers noted some improvement in infrastructure and working conditions, they still considered them to be widely inadequate. In Malawi, as in similar resource poor countries, greater attention needs to be given to the health system constraints to delivering health care. Removal of these constraints should receive priority over the considerable focus on the development and implementation of essential packages of

  19. Physical activity participation and constraints among athletic training students.

    PubMed

    Stanek, Justin; Rogers, Katherine; Anderson, Jordan

    2015-02-01

    Researchers have examined the physical activity (PA) habits of certified athletic trainers; however, none have looked specifically at athletic training students. To assess PA participation and constraints to participation among athletic training students. Cross-sectional study. Entry-level athletic training education programs (undergraduate and graduate) across the United States. Participants were 1125 entry-level athletic training students. Self-reported PA participation, including a calculated PA index based on a typical week. Leisure constraints and demographic data were also collected. Only 22.8% (252/1105) of athletic training students were meeting the American College of Sports Medicine recommendations for PA through moderate-intensity cardiorespiratory exercise. Although 52.3% (580/1105) were meeting the recommendations through vigorous-intensity cardiorespiratory exercise, 60.5% (681/1125) were meeting the recommendations based on the combined total of moderate or vigorous cardiorespiratory exercise. In addition, 57.2% (643/1125) of respondents met the recommendations for resistance exercise. Exercise habits of athletic training students appear to be better than the national average and similar to those of practicing athletic trainers. Students reported structural constraints such as lack of time due to work or studies as the most significant barrier to exercise participation. Athletic training students experienced similar constraints to PA participation as practicing athletic trainers, and these constraints appeared to influence their exercise participation during their entry-level education. Athletic training students may benefit from a greater emphasis on work-life balance during their entry-level education to promote better health and fitness habits.

  20. Causality constraints in conformal field theory

    DOE PAGES

    Hartman, Thomas; Jain, Sachin; Kundu, Sandipan

    2016-05-17

    Causality places nontrivial constraints on QFT in Lorentzian signature, for example fixing the signs of certain terms in the low energy Lagrangian. In d dimensional conformal field theory, we show how such constraints are encoded in crossing symmetry of Euclidean correlators, and derive analogous constraints directly from the conformal bootstrap (analytically). The bootstrap setup is a Lorentzian four-point function corresponding to propagation through a shockwave. Crossing symmetry fixes the signs of certain log terms that appear in the conformal block expansion, which constrains the interactions of low-lying operators. As an application, we use the bootstrap to rederive the well knownmore » sign constraint on the (Φ)4 coupling in effective field theory, from a dual CFT. We also find constraints on theories with higher spin conserved currents. As a result, our analysis is restricted to scalar correlators, but we argue that similar methods should also impose nontrivial constraints on the interactions of spinning operators« less