Former WHK Intern Returns to NCI at Frederick as Earl-Stadtman Investigator | Poster

Cancer.gov

The Laboratory of Cell and Developmental Signaling (LCDS) recently welcomed John Brognard, Ph.D., as the new Earl-Stadtman Investigator. While Brognard is new to this role, he is not new to NCI at Frederick. In high school, Brognard was a Werner H. Kirsten Student Intern in what was formerly known as the ABL research program, where he worked under Bob Moschel, Ph.D., senior investigator, and Gary Pauly, Ph.D., currently a staff scientist in the Chemical Biology Laboratory.

Attributes of colleges and schools of pharmacy in the United States.

PubMed

Knapp, David A; Knapp, Deanne E

2009-08-28

To compare the attributes of US colleges and schools of pharmacy and describe the extent of change to the pharmacy education enterprise associated with the addition of new schools. Attributes analyzed included whether the college or school of pharmacy was old or new, public or private, secular or faith-based, and on or not on an academic health center (AHC) campus; had 3- or 4- year programs; and had PhD students enrolled. PharmD student enrollment-to-faculty ratios and junior-to-senior faculty ratios also were examined. Of the new colleges/schools, 76% were private and 79% were not located on a campus with an AHC; 6% had PhD enrollment compared with 80% of old colleges/schools. Faculty ratios were related to several college/school attributes, including the presence or absence of PhD students and whether the college/school was public or private. Attributes of new colleges and schools of pharmacy have changed the overall profile of all colleges and schools of pharmacy. For example, smaller percentages of all colleges and schools of pharmacy are public and have PhD enrollees.

Report on the International PhD School ''Science and Technology with the E-ELT''

NASA Astrophysics Data System (ADS)

Bono, G.; Hook, I.; Ramsay, S.

2015-12-01

This international PhD school in the F. Lucchin cycle was the first to bring together Masters and PhD students with an interest in all aspects of the science and technology of the European Extremely Large Telescope (E-ELT). It was fitting that this school was held within a year of the project formally entering the construction phase. An overview of the topics covered during the school is presented.

Status of PharmD/PhD Programs in Colleges of Pharmacy: The University of Tennessee Dual PharmD/PhD Program

PubMed Central

Gourley, Dick R.; Rowell, Crescent; Wingate, LaMarcus; Yates, Charles R.; Gourley, Greta K.; Miller, Duane D.; Vleet, Van

2006-01-01

Objectives To describe the University of Tennessee PharmD/PhD program and assess the prevalence and characteristics of PharmD/PhD programs in the United States. Methods Survey instruments were mailed in May 2004 to UT dual-degree program participants and deans of US colleges and schools of pharmacy. Results University of Tennessee PharmD/PhD students completed more than 30 hours of graduate credit before obtaining their PharmD and 72.2% agreed or strongly agreed that the program met their professional goals. More than 40% of US pharmacy colleges and schools have or plan to have PharmD/PhD programs. A wide variation exists in the level of integration, PhD concentrations offered, entrance requirements, and student benefits. Most schools with PharmD/PhD programs had few students enrolled in the program, but attrition rates were low (<20%) for 69% of the schools. Conclusions Dual-degree programs attract and retain pharmacy students in research programs and 47.6% of graduates entered academia and industry. PMID:17149422

The Effect of Level of Information as Presented by Different Technologies on Students' Understanding of Acid, Base, and pH Concepts.

ERIC Educational Resources Information Center

Nakhleh, Mary B.; Krajcik, Joseph S.

Within high school chemistry the topic of acids, bases, and pH is particularly challenging because robust understanding of the topic depends heavily on the student possessing deep concepts of atoms, molecules, ions, and chemical reactions. Since knowledge is acquired and stored in a dynamic structure, it was investigated in this study how…

The NASA Climate Change Research Initiative - A Scientist's Perspective

NASA Astrophysics Data System (ADS)

LeGrande, A. N.; Pearce, M. D.; Dulaney, N.; Kelly, S. M.

2017-12-01

For the last four years, I have been a lead mentor in the NASA GISS Climate Change Research Initiative (CCRI) program, a component in the NASA GSFC Office of Education portfolio. It creates a multidisciplinary; vertical research team including a NYC metropolitan teacher, graduate student, undergraduate student, and high school student. While the college and high school members of this research team function like a more traditional internship component, the teacher component provides a powerful, direct way to connect state-of-the art research with students in the classroom. Because the teacher internship lasts a full year, it affords a similar relationship with a teacher that normally only exists between a PhD student and scientist. It also provides an opportunity to train the teacher in using the extensive data archives and other information maintained on NASA's publicly available websites. This time and access provide PhD-level training in the techniques and tools used in my climate research to the high school teacher. The teacher then uses his/her own pedagogical expertise to translate these techniques into age/level appropriate lesson plans for the classroom aligned with current STEM education trends and expectations. Throughout the process, there is an exchange of knowledge between the teacher and scientist that is very similar to the training given to PhD level graduate students. The teacher's understanding of the topic and implementation of the tools is done under a very close collaboration with the scientist supervisor and the NASA Education Program Specialist. This vertical team model encourages collegial communication between teachers and learners from many different educational levels and capitalizes on the efficacy of near peer mentoring strategies. This relationship is important in building trust through the difficult, iterative process that results in the development of highly accurate and quality (continuously discussed and vetted) curriculum composed of science modules on very sophisticated STEM education topics tailored and customized for a high school student audience. This program has thus very meaningful broad impacts with a scientist being able to reach and inspire 150 or more students per year through the expert collaboration of the high school teacher to scientist partnership. PANELIST

Former WHK Intern Returns to NCI at Frederick as Earl-Stadtman Investigator | Poster

Cancer.gov

The Laboratory of Cell and Developmental Signaling (LCDS) recently welcomed John Brognard, Ph.D., as the new Earl-Stadtman Investigator. While Brognard is new to this role, he is not new to NCI at Frederick. In high school, Brognard was a Werner H. Kirsten Student Intern in what was formerly known as the ABL research program, where he worked under Bob Moschel, Ph.D., senior

Middle School and pH?

ERIC Educational Resources Information Center

Herricks, Susan

2007-01-01

A local middle school requested that the Water Center of Advanced Materials for Purification of Water With Systems (WaterCAMPWS), a National Science Foundation Science and Technology Center, provide an introduction to pH for their seventh-grade water-based service learning class. After sorting through a multitude of information about pH, a…

Serious Game Motivation in an EFL Classroom in Chinese Primary School

ERIC Educational Resources Information Center

Anyaegbu, Ruphina; Ting, Wei; Li, Yi

2012-01-01

This paper is a report on the findings of a qualitative PhD pilot research study on the integration of Serious Games specifically Mingoville to motivate the Chinese primary students in an EFL classrooms. It was carried out in two primary schools: the students are both from low and high income families respectively in Jiangsu Province, PR, China.…

Shared responsibility: school nurses' experience of collaborating in school-based interprofessional teams.

PubMed

Reuterswärd, Marina; Hylander, Ingrid

2017-06-01

The Swedish Education Act (2011) mandated a new combination of services to boost students' physical health, their mental health and special education through interprofessional pupil health and well-being (PH) teams. For Swedish school nurses, providing these services presents new challenges. To describe how Swedish school nurses experience their work and collaboration within the interprofessional PH teams. Twenty-five school nurses (SNs) were interviewed in five focus groups. Content analysis was used to examine the data and to explore SNs' workplace characteristics by using the components of the sense of coherence (SOC) framework. SNs' experiences of work and collaboration within PH teams can be described using three domains: the expectations of others regarding SNs' roles, SNs' contributions to pupils' health and well-being, and collaboration among SNs within PH teams. The results indicate a discrepancy between SNs' own experiences of their contribution and their experiences of other professionals' expectations regarding those contributions. Some duties were perceived as expected, comprehensible, manageable and meaningful, while other duties - though expected - were perceived as less meaningful, taking time away from school-related matters. Other duties that were not explicitly expected - promoting general health and creating safety zones for pupils, teachers and parents, for example - were nonetheless perceived as meaningful. Collaboration within PH teams was considered meaningful, comprehensible and manageable only if the objectives of the team meetings were clear, if other professionals were available and if professional roles on the team were clearly communicated. The SNs reported a lack of clarity regarding their role in PH and its implementation in schools, indicating that professionals in PH teams need to discuss collaboration so as to find their niche given the new conditions. SOC theory emerged as a useful framework for discussing concrete work-related factors in the school environment. © 2016 Nordic College of Caring Science.

Performing International Outreach: PhUn Week in an Australian Primary School

ERIC Educational Resources Information Center

Halpin, Patricia A.

2017-01-01

Physiology Understanding (PhUn) Week is an annual science outreach program sponsored by the American Physiological Society in which K-12 students learn about physiology through meeting a physiologist and performing an experiment. Performing PhUn Week at an Australian private primary school during a family vacation in 2014 enabled me to receive a…

Positive affect, negative affect, and physiological hyperarousal among referred and nonreferred youths.

PubMed

Laurent, Jeff; Joiner, Thomas E; Catanzaro, Salvatore J

2011-12-01

The Positive and Negative Affect Scale for Children (PANAS-C) and the Physiological Hyperarousal Scale for Children (PH-C) seem ideal measures for school mental health screenings, because they are theory based, psychometrically sound, and brief. This study provides descriptive information and preliminary cutoff scores in an effort to increase the practical utility of the measures. Scores on the PANAS-C Positive Affect (PA) and Negative Affect (NA) scales and the PH-C were compared for a general sample of schoolchildren (n = 226), a group of students referred for special education services (n = 83), and youths on an inpatient psychiatric unit (n = 37). Expected patterns of scores emerged for the general school and referred school samples, although only scores on the PH-C were statistically significantly different. Differences in scores between the general school and inpatient samples were significant for all 3 scales. Differences in scores between the referred school and inpatient samples were significant for the NA scale and the PH-C but not for the PA scale. In addition, we used traditional self-report measures to form groups of normal, anxious, depressed, and mixed anxious and depressed youths. Again, predicted general patterns of PA, NA and PH scores were supported, although statistical differences were not always evident. In particular, scores on the PH-C for the anxious and depressed groups were inconsistent with predictions. Possible reasons related to sample and scale issues are discussed. Finally, preliminary cutoff scores were proposed for the PANAS-C scales and the PH-C.

Publishing scientific papers based on Master's and Ph.D. theses from a small scientific community: case study of Croatian medical schools.

PubMed

Frković, Vedran; Skender, Tomislav; Dojćinović, Bojan; Bilić-Zulle, Lidija

2003-02-01

To evaluate publishing activity of medical doctors after they have obtained Master's or Ph.D. degree at the Rijeka and Zagreb University Schools of Medicine in Croatia, and establish the number of journal articles based on these theses. Data on Master's and Ph.D. theses defended at the Rijeka and Zagreb University Schools of Medicine in the 1990-1999 period were collected by hand-search of the archive. MEDLINE and Current Contents databases were searched for journal articles resulting from the theses. During the 10-year period, 1,535 Master's and 634 Ph.D. theses were defended at the Rijeka and Zagreb University Schools of Medicine (253 Master's and 138 Ph.D. theses from Rijeka and 1,282 Master's and 496 Ph.D. theses from Zagreb). There were 201 (14%) Master's and 218 (34%) Ph.D. theses that resulted in articles published in journals indexed in MEDLINE (13% of Master's and 11% of Ph.D. theses from Rijeka, and 14% of Master's and 41% of Ph.D. theses from Zagreb). Also, 97 (6%) Master's and 129 (20%) Ph.D. theses that resulted in articles published in Current Contents journals (8% of Master's and 6% of Ph.D. theses from Rijeka, and 6% of Master's and 24% of Ph.D. theses from Zagreb). There was no significant difference between the two Universities with respect to published articles based on Master's theses, but there were significantly more articles from Ph.D. theses in Zagreb (p<0.001). Most of the theses resulted in a single publication (95%), 19 (5%) in 2, and 2 in 3 publications. Out of all 453 journal articles, 31% were published in Croatian and 69% in international journals. Most Croatian Master's and Ph.D. theses are not made available to the scientific community. There should be more institutional effort directed at the stimulation of postgraduate students to publish their scientific work.

Sonic Fatigue Design Guide for Military Aircraft

DTIC Science & Technology

1975-05-01

on Sonic Fatigue Esti- mates," H.Sc. Thesis , School of Engineering, Air Force Institute of Technology, Air University, United States Air Force...ONR) from ZhTF, 15, pp. 63-70, 1945. 2. Krishnamurty, K.; "Sound Radiation from Surface Cutouts in High Speed Flow," Ph.D. Thesis , California Institute...Turbulence," Ph.D. Thesis , University of London, 1962. 10. Gibson, J. S.; ’’Boundary Layer ý’-lse Measurements on a Large Turbofan Aircraft," Paper No

Role of institutional climate in fostering diversity in biomedical research workforce: a case study.

PubMed

Butts, Gary C; Hurd, Yasmin; Palermo, Ann-Gel S; Delbrune, Denise; Saran, Suman; Zony, Chati; Krulwich, Terry A

2012-01-01

This article reviews the barriers to diversity in biomedical research and describes the evolution of efforts to address climate issues to enhance the ability to attract, retain, and develop underrepresented minorities, whose underrepresentation is found both in science and medicine, in the graduate-school biomedical research doctoral programs (PhD and MD/PhD) at Mount Sinai School of Medicine. We also describe the potential beneficial impact of having a climate that supports diversity and inclusion in the biomedical research workforce. The Mount Sinai School of Medicine diversity-climate efforts are discussed as part of a comprehensive plan to increase diversity in all institutional programs: PhD, MD/PhD, and MD, and at the residency, postdoctoral fellow, and faculty levels. Lessons learned from 4 decades of targeted programs and activities at the Mount Sinai School of Medicine may be of value to other institutions interested in improving diversity in the biomedical science and academic medicine workforce. © 2012 Mount Sinai School of Medicine.

Parent weight change predicts child weight change in family-based weight control program for pre-school children (Buffalo healthy tots)

USDA-ARS?s Scientific Manuscript database

Title: PARENT WEIGHT CHANGE PREDICTS CHILD WEIGHT CHANGE IN FAMILY-BASED WEIGHT CONTROL PROGRAM FOR PRE-SCHOOL CHILDREN (BUFFALO HEALTHY TOTS), Teresa Quattrin, MOl, James N Roemmich, PhDI, Rocco Paluch, MAl, Jihnhee Yu, PhD2, Leonard H Epstein, PhDI and Michelle A Ecker, RD, CDEI . lpediatrics, Uni...

Factors Influencing School Closure and Dismissal Decisions: Influenza A (H1N1), Michigan 2009

ERIC Educational Resources Information Center

Dooyema, Carrie A.; Copeland, Daphne; Sinclair, Julie R.; Shi, Jianrong; Wilkins, Melinda; Wells, Eden; Collins, Jim

2014-01-01

Background: In fall 2009, many US communities experienced school closures during the influenza A H1N1 pandemic (pH1N1) and the state of Michigan reported 567 closures. We conducted an investigation in Michigan to describe pH1N1-related school policies, practices, and identify factors related to school closures. Methods: We distributed an online…

Research on the River.

ERIC Educational Resources Information Center

Steckelberg, Marie L.; Hoadley, Michael R.; Thompson, Ray; Martin, Patricia; Bormann, Gene

2000-01-01

Introduces a research project on water quality in which students from two different high schools collaborate with university science methods students. Includes the analyses of air temperature, water temperature, fecal coliform, dissolved oxygen, phosphate level, turbidity, and pH level. Integrates biology, environmental sciences, physical…

Enhancing Postgraduate Learning and Teaching: Postgraduate Summer School in Dairy Science

PubMed Central

Gabai, Gianfranco; Morgante, Massimo; Gallo, Luigi

2014-01-01

Dairy science is a multidisciplinary area of scientific investigation and Ph.D. students aiming to do research in the field of animal and/or veterinary sciences must be aware of this. Ph.D. students often have vast spectra of research interests, and it is quite challenging to satisfy the expectation of all of them. The aim of this study was to establish an international Ph.D. training program based on research collaboration between the University of Sydney and the University of Padova. The core component of this program was a two-week Postgraduate Summer School in Dairy Science, which was held at the University of Padova, for Ph.D. students of both universities. Therefore, we designed a program that encompassed seminars, workshops, laboratory practical sessions, and farm visits. Participants were surveyed using a written questionnaire. Overall, participants have uniformly praised the Summer School calling it a rewarding and valuable learning experience. The Ph.D. Summer School in Dairy Science provided its participants a positive learning experience, provided them the opportunity to establish an international network, and facilitated the development of transferable skills. PMID:24575312

Educational Training and Careers of PH.D. Holders. Academic Training and Occupational Mobility: Ph.D.'s Often Find Other Scientific Fields Greener. Final Report.

ERIC Educational Resources Information Center

Morris, Jeffrey

The occupational transferability of skills learned in school and on the job has been studied very little. This paper reports some estimates of the monetary trade-off between specialization and occupational flexibility in the Ph.D's choice of major at undergraduate and graduate school. These estimates are based for the most part on multiple…

Assisting the High Administrative Court in Restricting Too Broad a Concept of Academic Judgment.

PubMed

Cardao-Pito, Tiago

2016-01-01

I have received substantial monetary compensation and a formal apology from my first doctoral school, and a Ph.D. from another university. This essay describes my personal view on discussing the boundaries of academic judgment and research supervision with the ombudsman agency for higher education, and at the High Administrative Court of England and Wales. The Court's judicial doctrine addresses substantial research accountability matters. It clarifies that although the Court and ombudsman agency must not interfere with academic judgment, not everything done by an academic can be considered as academic judgment. A Ph.D. supervisor can seriously fail to perform his/her duties.

Use of Nonpharmaceutical Interventions to Reduce Transmission of 2009 Pandemic Influenza A (pH1N1) in Pennsylvania Public Schools

ERIC Educational Resources Information Center

Miller, Jeffrey R.; Short, Vanessa L.; Wu, Henry M.; Waller, Kirsten; Mead, Paul; Kahn, Emily; Bahn, Beth A; Dale, Jon W.; Nasrullah, Muazzam; Walton, Sabrina E.; Urdaneta, Veronica; Ostroff, Stephen; Averhoff, Francisco

2013-01-01

Background: School-based recommendations for nonpharmaceutical interventions (NPIs) were issued in response to the threat of 2009 pandemic influenza A (pH1N1). The implementation and effectiveness of these recommendations has not been assessed. Methods: In November 2009, a Web-based survey of all Pennsylvania public schools was conducted to assess…

Physics Trends flyers & high school flyers

NASA Astrophysics Data System (ADS)

White, Susan C.

2016-03-01

Since 2000, we have published a series of flyers highlighting various data of interest to physics faculty members and students. For example, our Fall 2015 Physics Trends flyers display the employment sectors where physics bachelor's degree recipients work, the knowledge used frequently by mid-career PhD physicists working primarily in private sector jobs, and the proportion of women among physics faculty members. We have recently added a new resource for high school physics teachers: flyers focusing on high school physics. PDFs of both the Physics Trends and high school flyers are available for download at: www.aip.org/statistics/physics-trends and www.aip.org/statistics/highschool. We also have a limited number of printed copies of the Physics Trends flyers which we are happy to send to you upon request. We appreciate the responses from each of you who has helped us collect these data. Next month we will look at Hispanic representation among bachelor's degree recipients in physical sciences and engineering.

DNA Microarray Wet Lab Simulation Brings Genomics into the High School Curriculum

PubMed Central

Zanta, Carolyn A.; Heyer, Laurie J.; Kittinger, Ben; Gabric, Kathleen M.; Adler, Leslie

2006-01-01

We have developed a wet lab DNA microarray simulation as part of a complete DNA microarray module for high school students. The wet lab simulation has been field tested with high school students in Illinois and Maryland as well as in workshops with high school teachers from across the nation. Instead of using DNA, our simulation is based on pH indicators, which offer many ideal teaching characteristics. The simulation requires no specialized equipment, is very inexpensive, is very reliable, and takes very little preparation time. Student and teacher assessment data indicate the simulation is popular with both groups, and students show significant learning gains. We include many resources with this publication, including all prelab introductory materials (e.g., a paper microarray activity), the student handouts, teachers notes, and pre- and postassessment tools. We did not test the simulation on other student populations, but based on teacher feedback, the simulation also may fit well in community college and in introductory and nonmajors' college biology curricula. PMID:17146040

DNA microarray wet lab simulation brings genomics into the high school curriculum.

PubMed

Campbell, A Malcolm; Zanta, Carolyn A; Heyer, Laurie J; Kittinger, Ben; Gabric, Kathleen M; Adler, Leslie; Schulz, Barbara

2006-01-01

We have developed a wet lab DNA microarray simulation as part of a complete DNA microarray module for high school students. The wet lab simulation has been field tested with high school students in Illinois and Maryland as well as in workshops with high school teachers from across the nation. Instead of using DNA, our simulation is based on pH indicators, which offer many ideal teaching characteristics. The simulation requires no specialized equipment, is very inexpensive, is very reliable, and takes very little preparation time. Student and teacher assessment data indicate the simulation is popular with both groups, and students show significant learning gains. We include many resources with this publication, including all prelab introductory materials (e.g., a paper microarray activity), the student handouts, teachers notes, and pre- and postassessment tools. We did not test the simulation on other student populations, but based on teacher feedback, the simulation also may fit well in community college and in introductory and nonmajors' college biology curricula.

Columbia's Bridge to the Ph.D. Program: A research-focused initiative facilitating the transition to graduate school

NASA Astrophysics Data System (ADS)

Agüeros, Marcel A.

2015-01-01

Columbia University's Bridge to the Ph.D. in the Natural Sciences Program aims to enhance the participation of students from underrepresented groups in Ph.D. programs. To achieve this, the Bridge Program provides an intensive research, coursework, and mentoring experience to post-baccalaureates seeking to strengthen their graduate school applications and to prepare for the transition into graduate school. To date, 20 Bridge Program alumni --- including four in astronomy --- have gone on to Ph.D. programs at Columbia, the University of Michigan, Johns Hopkins, the University of Washington, Albert Einstein, Yale, and SUNY-Albany, among others. In this talk, I will touch on some of the connections between Pre-MAP and the Bridge Program, and particularly how my involvement in the former prepared me to lead the latter.

The Chemistry of Photographic Color Dye Formation

ERIC Educational Resources Information Center

Kahn, Bruce E.

2004-01-01

A laboratory activity that can be used at a number of levels from high school to college is discussed. This activity can be used to teach chemical concepts such as oxidation and reduction, stoichiometry, acids and bases, pH, nucleophilic reactions, conjugation, leaving groups, complexation, solubility, and reversibility.

Reef Education Evaluation: Environmental Knowledge and Reef Experience

ERIC Educational Resources Information Center

Stepath, Carl M.

2005-01-01

Background: The Reef education evaluation: environmental knowledge and reef experience report concerns PhD research about marine education, and the investigation of learning with high school students and the effect of coral reef monitoring marine experiential education interventions. The effectiveness of classroom learning and reef trips were…

Laboratory Connections: Review of Two Commercial Interfacing Packages.

ERIC Educational Resources Information Center

Powers, Michael H.

1989-01-01

Evaluates two Apple II interfacing packages designed to measure pH: (1) "Experiments in Chemistry" by HRM Software and (2) "Voltage Plotter III" by Vernier Software. Provides characteristics and screen dumps of each package. Reports both systems are suitable for high school or beginning college laboratories. (MVL)

Stronger Disciplinary Identities in Multidisciplinary Research Schools

ERIC Educational Resources Information Center

Geschwind, Lars; Melin, Göran

2016-01-01

In this study, two multidisciplinary Social Sciences and Humanities research schools in Sweden have been investigated regarding disciplinary identity-making. This study investigates the meetings between different disciplines around a common thematic area of study for Ph.D. students. The Ph.D. students navigate through a complex social and…

Educating future nursing scientists: Recommendations for integrating omics content in PhD programs.

PubMed

Conley, Yvette P; Heitkemper, Margaret; McCarthy, Donna; Anderson, Cindy M; Corwin, Elizabeth J; Daack-Hirsch, Sandra; Dorsey, Susan G; Gregory, Katherine E; Groer, Maureen W; Henly, Susan J; Landers, Timothy; Lyon, Debra E; Taylor, Jacquelyn Y; Voss, Joachim

2015-01-01

Preparing the next generation of nursing scientists to conduct high-impact, competitive, sustainable, innovative, and interdisciplinary programs of research requires that the curricula for PhD programs keep pace with emerging areas of knowledge and health care/biomedical science. A field of inquiry that holds great potential to influence our understanding of the underlying biology and mechanisms of health and disease is omics. For the purpose of this article, omics refers to genomics, transcriptomics, proteomics, epigenomics, exposomics, microbiomics, and metabolomics. Traditionally, most PhD programs in schools of nursing do not incorporate this content into their core curricula. As part of the Council for the Advancement of Nursing Science's Idea Festival for Nursing Science Education, a work group charged with addressing omics preparation for the next generation of nursing scientists was convened. The purpose of this article is to describe key findings and recommendations from the work group that unanimously and enthusiastically support the incorporation of omics content into the curricula of PhD programs in nursing. The work group also calls to action faculty in schools of nursing to develop strategies to enable students needing immersion in omics science and methods to execute their research goals. Copyright © 2015 Elsevier Inc. All rights reserved.

Understanding Ocean Acidification

ERIC Educational Resources Information Center

National Oceanic and Atmospheric Administration, 2011

2011-01-01

This curriculum module is designed for students who are taking high school chemistry. Students should already have some experience with the following: (1) Understanding and reading the pH scale; (2) Knowledge of the carbon cycle; (3) Using scientific notation to express large and small values; and (4) Reading chemical equations. This curriculum…

The Source Book of Marine Sciences.

ERIC Educational Resources Information Center

Beakley, John C.; And Others

Included is a teachers resource collection of 42 marine science activities for high school students. Both the biological and the physical factors of the marine environment are investigated, including the study of tides, local currents, microscope measuring, beaches, turbidity, sea water solids, pH, and salinity, marine bacteriology, microbiology,…

The Effects of Parenthood during Graduate School on PhD Recipients' Paths to the Professoriate: A Focus on Motherhood

ERIC Educational Resources Information Center

Kulp, Amanda M.

2016-01-01

This chapter focuses on graduate students who are parents, the career-related resources they gather during graduate school, and the influence of those resources on PhD-earning mothers' attainment of tenure-track faculty jobs at U.S. higher-education institutions.

A workshop on leadership for senior MD–PhD students

PubMed Central

Meador, Catherine B.; Parang, Bobak; Musser, Melissa A.; Haliyur, Rachana; Owens, David A.; Dermody, Terence S.

2016-01-01

Leadership skills are essential for a successful career as a physician-scientist, yet many MD–PhD training programs do not offer formal training in leadership. The Vanderbilt Medical Scientist Training Program (MSTP) previously established a 2-day leadership workshop that has been held biennially since 2006 for students in the first and second years of the graduate school portion of combined MD and PhD training (G1/G2 students). Workshop attendees have consistently rated this workshop as a highly effective experience. However, opportunities for structured training in leadership competencies during the subsequent 3–5 years of MD–PhD training are limited. Given the success of the G1/G2 leadership workshop and the need for continuity in this model of leadership training, we developed a half-day workshop for MSTP students in the clinical years of medical school (M3/M4 students) to foster continued training in leadership. Our workshop curriculum, based in part on original cases drafted by Vanderbilt MSTP students, provides concrete strategies to manage conflict and navigate leadership transitions in the physician-scientist career path. The curriculum emphasizes both short-term competencies, such as effective participation as a member of a clinical team, and long-term competencies, such as leadership of a research team, division, or department. Our inaugural senior leadership workshop, held in August, 2015, was judged by student participants to be well organized and highly relevant to leadership concepts and skills. It will be offered biennially in our training curriculum for M3 and M4 MSTP students. PMID:27499363

A workshop on leadership for senior MD-PhD students.

PubMed

Meador, Catherine B; Parang, Bobak; Musser, Melissa A; Haliyur, Rachana; Owens, David A; Dermody, Terence S

2016-01-01

Leadership skills are essential for a successful career as a physician-scientist, yet many MD-PhD training programs do not offer formal training in leadership. The Vanderbilt Medical Scientist Training Program (MSTP) previously established a 2-day leadership workshop that has been held biennially since 2006 for students in the first and second years of the graduate school portion of combined MD and PhD training (G1/G2 students). Workshop attendees have consistently rated this workshop as a highly effective experience. However, opportunities for structured training in leadership competencies during the subsequent 3-5 years of MD-PhD training are limited. Given the success of the G1/G2 leadership workshop and the need for continuity in this model of leadership training, we developed a half-day workshop for MSTP students in the clinical years of medical school (M3/M4 students) to foster continued training in leadership. Our workshop curriculum, based in part on original cases drafted by Vanderbilt MSTP students, provides concrete strategies to manage conflict and navigate leadership transitions in the physician-scientist career path. The curriculum emphasizes both short-term competencies, such as effective participation as a member of a clinical team, and long-term competencies, such as leadership of a research team, division, or department. Our inaugural senior leadership workshop, held in August, 2015, was judged by student participants to be well organized and highly relevant to leadership concepts and skills. It will be offered biennially in our training curriculum for M3 and M4 MSTP students.

Do They Enter the Workforce? Career Choices after an Undergrad Research Experience

NASA Astrophysics Data System (ADS)

Greco, S.; Wissel, S.; Zwicker, A.; Ortiz, D.; Dominguez, A.

2015-11-01

Students in undergrad research internships go on to grad school at rates of 50-75% (Lopatto, 2007;Russell, 2005). NSF studied its undergrad program and found that 74% of physics interns (67% for engineering) go to grad school. PPPL undergrad interns were tracked for 10 years. Only 3% of physics PhD candidates are studying plasma physics, but 23% of our alumni that entered grad school did so in plasma. AIP reports that 60% of physics majors go to grad school (AIP, 2012), but 95% of PPPL interns have gone on to grad schools. Several programs track enrollment in grad school. AIP compiles statistics of undergrads who enter grad school and PhD students who work in the field. There has been no study of interns that follows the path from undergrad to grad school and then on to employment. Our tracking shows that most not only complete their advanced degrees but also stay in STEM fields following their academic careers. 88% of them become part of the STEM workforce, higher than the 82% of all physics PhDs employed in physics after obtaining their degree (AIP, 2014). PPPL puts more students in grad school in physics, and specifically plasma physics, and a higher percentage of those grad students stay in the STEM workforce.

XIII Modave Summer School in Mathematical Physics

NASA Astrophysics Data System (ADS)

2017-09-01

The Modave Summer School on Mathematical Physics is a yearly summer school in topics of theoretical physics. Various topics ranging from quantum gravity and cosmology to theoretical particle physics and string theory. The school takes place in Modave, a charming village in the Belgian Ardennes close to Huy. Modave School is organised by PhD students for PhD students, and this makes it rather unique. The courses are taught by Post-Docs or late PhD students, and they are all made of pedagogical, basic blackboard lectures about recent topics in theoretical physics. Participants and lecturers eat and sleep in the same place where the lectures are given. The absence of senior members, and the fact of spending day and night together in an isolated, peaceful place contribute to creating an informal atmosphere and facilitating interactions. Lectures of the thirteenth edition are centered around the following subjects: bulk reconstruction in AdS/CFT, twistor theory, AdS_2/CFT_1 and SYK, geometry and topology, and asymptotic charges.

The Gatsby Plant Science Summer School: Inspiring the Next Generation of Plant Science Researchers[OA

PubMed Central

Levesley, Aurora; Jopson, Juliet; Knight, Celia

2012-01-01

We provide evidence from a 5-year study to show that a single concerted effort at the start of undergraduate study can have a clear and lasting effect on the attitudes of students toward plant science. Attendance at a week-long residential plant science summer school in the first year of an undergraduate degree resulted in many students changing courses to include more plant science and increased numbers of graduates selecting plant-based PhDs. The evidence shows that the Gatsby Plant Science Summer School has increased the pool of high-quality plant science related PhD applicants in the UK and has had a positive impact on students’ career aspirations. The results are discussed within the context of enhancing the pipeline of future plant scientists and reversing the decline of this vulnerable and strategically important subject relevant to addressing food security and other major global challenges. We have shown that a single well-designed and timely intervention can influence future student behavior and as such offers a framework of potential use to other vulnerable disciplines. PMID:22534129

The Gatsby Plant Science Summer School: inspiring the next generation of plant science researchers.

PubMed

Levesley, Aurora; Jopson, Juliet; Knight, Celia

2012-04-01

We provide evidence from a 5-year study to show that a single concerted effort at the start of undergraduate study can have a clear and lasting effect on the attitudes of students toward plant science. Attendance at a week-long residential plant science summer school in the first year of an undergraduate degree resulted in many students changing courses to include more plant science and increased numbers of graduates selecting plant-based PhDs. The evidence shows that the Gatsby Plant Science Summer School has increased the pool of high-quality plant science related PhD applicants in the UK and has had a positive impact on students' career aspirations. The results are discussed within the context of enhancing the pipeline of future plant scientists and reversing the decline of this vulnerable and strategically important subject relevant to addressing food security and other major global challenges. We have shown that a single well-designed and timely intervention can influence future student behavior and as such offers a framework of potential use to other vulnerable disciplines.

The Added Value of a PhD in Medicine--PhD Students' Perceptions of Acquired Competences

ERIC Educational Resources Information Center

Anttila, Henrika; Lindblom-Ylänne, Sari; Lonka, Kristi; Pyhältö, Kirsi

2015-01-01

PhD in the field of medicine is more common than in any other domain. Many medical doctors are driven towards PhD, but also students with other backgrounds (usually MSc) are conducting a PhD in medical schools. Higher education has invested a lot in developing generic and research competences. Still little is known about how PhD students…

Katherine Hurst | NREL

Science.gov Websites

, followed by the completion of a M.S. in Chemical Engineering from the Colorado School of Mines. She received her Ph.D. in Chemical Engineering. Her thesis, which was performed at NREL under the direction of 2001-2005 Ph.D. Chemical Engineering, Colorado School of Mines, Golden, CO Research Fellowship at the

Report of the Survey of Howard University: The Graduate School and Selected Ph.D. Programs.

ERIC Educational Resources Information Center

Office of Education (DHEW), Washington, DC.

Results of the Office of Education's Bureau of Higher and Continuing Education's inspection of Howard University's Graduate School and the Ph.D. program are presented. The inspection was performed by conducting a survey of the administrative staff, the faculty, and student body, and by examining relevant facilities, laboratories, equipment,…

Prairie View A&M/Baylor College of Medicine SMART Summer Undergraduate Prostate Cancer Research Project

DTIC Science & Technology

2008-04-01

prepares to take the MCAT and GRE exams and apply for MD/Ph.D. and DO/Ph.D, programs. 2007 Participants Alem Tewoldeberhan was accepted to the...apply to medical school. Mark Williams, II intends to work as a technician while he improves his MCAT score and applies to medical school. Mark

An Impact Analysis of Regional Industry-University Interactions: The Case of Industrial PhD Schools

ERIC Educational Resources Information Center

Gustavsson, Linda; Nuur, Cali; Söderlind, Johan

2016-01-01

The authors discuss Triple Helix collaborations in the context of regional competitiveness. Through an exploratory case study, they identify and analyse the impact of the establishment of industrial PhD schools for participating industry and universities. The study was conducted in Sweden in 2014 and focuses on three industry-university…

An Impact Analysis of Regional Industry--University Interactions: The Case of Industrial PhD Schools

ERIC Educational Resources Information Center

Gustavsson, Linda; Nuur, Cali; Söderlind, Johan

2016-01-01

The authors discuss Triple Helix collaborations in the context of regional competitiveness. Through an exploratory case study, they identify and analyse the impact of the establishment of industrial PhD schools for participating industry and universities. The study was conducted in Sweden in 2014 and focuses on three industry--university…

Integrating Interactive Simulations into the Mathematics Classroom: Supplementing, Enhancing, or Driving?

ERIC Educational Resources Information Center

Findley, Kelly; Whitacre, Ian; Hensberry, Karina

2017-01-01

High-tech tools can be integrated to serve a number of purposes in the mathematics classroom, with different purposes being appropriate for different learning goals. We focus specifically on the various purposes for interactive simulations (sims). This study followed three experienced middle-school mathematics teachers integrating PhET sims into…

Reflections on where the Boys Are

ERIC Educational Resources Information Center

Behrend, Carl

2009-01-01

Young females have "arrived" in regard to graduating from high school and attending and graduating from college. More females are currently earning PhD's than their male counterparts. Female students have been encouraged and nurtured to become a confident, task-oriented, organized group of achievers who are applying to college in record numbers.…

A Guided-Inquiry pH Laboratory Exercise for Introductory Biological Science Laboratories

ERIC Educational Resources Information Center

Snodgrass, Meagan A.; Lux, Nicholas; Metz, Anneke M.

2011-01-01

There is a continuing need for engaging inquiry-based laboratory experiences for advanced high school and undergraduate biology courses. The authors describe a guided-inquiry exercise investigating the pH-dependence of lactase enzyme that uses an inexpensive, wide-range buffering system, lactase dietary supplement, over-the-counter glucose test…

The Notion of Scientific Knowledge in Biology

ERIC Educational Resources Information Center

Morante, Silvia; Rossi, Giancarlo

2016-01-01

The purpose of this work is to reconsider and critically discuss the conceptual foundations of modern biology and bio-sciences in general, and provide an epistemological guideline to help framing the teaching of these disciplines and enhancing the quality of their presentation in High School, Master and Ph.D. courses. After discussing the…

Using Acid-Base Reagent Problems as a High School Science Research Activity.

ERIC Educational Resources Information Center

Schlenker, Richard M.; Cullen, David; Schlenker, Karl R.

1999-01-01

Describes an open-ended activity in which students try to determine the factors that contribute to an unusual chemical reaction. Uses a case study approach to show students how the presence of chlorine in tap water can interfere with a pH indicator. Includes assessment guidelines and extension activities. (WRM)

A Multiattributes Approach for Ranking PhD Programs

ERIC Educational Resources Information Center

Urbancic, Frank R.

2008-01-01

In its plan to combat the PhD shortage crisis, the Association to Advance Collegiate Schools of Business International (AACSB; 2003) has called for the development of PhD program rankings to serve as incentives for academic institutions to invest more in PhD programs, thereby counterbalancing the disproportionate influence of master of business…

Preparing Postbaccalaureates for Entry and Success in Biomedical PhD Programs

PubMed Central

Hall, Joshua D.; Harrell, Jessica R.; Cohen, Kimberley W.; Miller, Virginia L.; Phelps, Patricia V.; Cook, Jeanette G.

2016-01-01

Certain racial and ethnic groups, individuals with disabilities, and those from low socioeconomic backgrounds remain underrepresented (UR) in the biomedical sciences. This underrepresentation becomes more extreme at each higher education stage. To support UR scholars during the critical transition from baccalaureate to PhD, we established an intensive, 1-yr postbaccalaureate training program. We hypothesized that this intervention would strengthen each participant’s competitiveness for leading PhD programs and build a foundation of skills and self-efficacy important for success during and after graduate school. Scholar critical analysis skills, lab technique knowledge, and Graduate Record Examination scores all improved significantly during the program. Scholars reported significant confidence growth in 21 of 24 categories related to success in research careers. In 5 yr, 91% (41/45) of scholars transitioned directly into PhD programs. Importantly, 40% (18/45) of participating postbaccalaureate scholars had previously been declined acceptance into graduate school; however, 17/18 of these scholars directly entered competitive PhD programs following our training program. Alumni reported they were “extremely well” prepared for graduate school, and 95% (39/41) are currently making progress to graduation with a PhD. In conclusion, we report a model for postbaccalaureate training that could be replicated to increase participation and success among UR scholars in the biomedical sciences. PMID:27496358

The Graduate School of Climate Sciences, University of Bern

NASA Astrophysics Data System (ADS)

Martin, L.

2012-04-01

The Graduate School of Climate Sciences, University of Bern, offers a specialised M.Sc. and a Ph.D. study programme in climate sciences. The graduate school has a highly interdisciplinary profile involving not only natural sciences, but also humanities/history, economics and law. The ten participating institutes with a total of 45 academics provide expertise in long-term climate variability, climate modelling, climate reconstruction, predictability of the future climate and extreme events, the impact of climate change on ecosystems and climate risks for society and economy. The graduate school is fully compliant with the Bologna Accords and collaborates closely with the sister institution C2SM at ETH Zurich by, e.g., jointly organised lectures. There are currently 23 master and 37 doctoral students in the programme. These originate from the University of Bern (28 %), from other Swiss universities (30 %) and from foreign universities (42 %). Comprehensive information about the Graduate School of Climate Sciences is available at http://www.climatestudies.unibe.ch . The M.Sc. in Climate Sciences programme (120 ECTS credits) is designed to attract students from all disciplines in natural sciences and offers them a tailor-made curriculum to reach their career aspirations. The students make their own course selection according to their profile envisaged (specialised versus broad education) and ideally already guided by a job perspective. Selecting the courses and the topic of the master thesis they specialise in one of five fields: climate and earth system science; atmospheric science; economics; economic, social and environmental history; statistics. Several courses are organised jointly with public authorities and the private industry, e.g. from experts working in the insurance business, in weather forecasting or in environmental pollution control. This provides the students hands-on experience and contacts to future employers. The master thesis (60 ECTS) involves the students in an ongoing research project and gives them the opportunity to collaborate with experienced scientists in a team. Alternatively, a short thesis (30 ECTS) may be combined with an internship (30 ECTS) at another university, in the private sector or in the administration. A bachelor degree in any field of science at university level (B.A. for specialisation in economics or history) or an equivalent degree is required for admission to the M.Sc. programme. The teaching language is English. The Ph.D. in Climate Sciences is research oriented and consists mainly of 3 to 4 years full time work in a project within one of the institutes involved in the Graduate School of Climate Sciences. The Ph.D. programme is research oriented and has a compulsory module of 12 ECTS credits containing workshops (professional skills), a summer school, an international conference, colloquia, seminars and optionally lectures. The compulsory module gives the Ph.D. students the opportunity to build up their own network in the local and international research community. The Ph.D. thesis is usually written in the form of research articles in international peer reviewed journals. A M.Sc. or an equivalent academic degree is conditional for admission to the Ph.D. programme.

Attrition during graduate medical education: medical school perspective.

PubMed

Andriole, Dorothy A; Jeffe, Donna B; Hageman, Heather L; Klingensmith, Mary E; McAlister, Rebecca P; Whelan, Alison J

2008-12-01

To identify predictors of attrition during graduate medical education (GME) in a single medical school cohort of contemporary US medical school graduates. Retrospective cohort study. Single medical institution. Recent US allopathic medical school graduates. Attrition from initial GME program. Forty-seven of 795 graduates (6%) did not complete the GME in their initial specialty of choice. At bivariate analysis, attrition was associated with election to the Alpha Omega Alpha Honor Medical Society, being an MD-PhD degree holder, and specialty choice (all P < .05). Attrition was not associated with graduation year (P = .91), sex (P = .67), or age (P = .12). In a multivariate logistic regression model, MD-PhD degree holder (odds ratio, 3.43; 95% confidence interval, 1.27-9.26; P = .02), election to Alpha Omega Alpha (2.19; 1.04-4.66; P = .04), choice of general surgery for GME (5.32; 1.98-14.27; P < .001), and choice of 5-year surgical specialty including those surgical specialties with a GME training requirement of 5 years or longer (2.74; 1.16-6.44; P = .02) each independently predicted greater likelihood of attrition. Academically highly qualified graduates and graduates who chose training in general surgery or in a 5-year surgical specialty were at increased risk of attrition during GME.

A Reconsideration of the Ph.D.

ERIC Educational Resources Information Center

Nichols, Roy F.

1967-01-01

One of the major problems in doctoral education, the shortage of Ph.D. holders, is discussed. A brief history of the German influence on graduate schools in the United States is given to suggest the reasons why the traditional Ph.D. is not designed for present needs. Suggestions are given for a more effective Ph.D. curriculum which will meet the…

Use of nonpharmaceutical interventions to reduce transmission of 2009 pandemic influenza A (pH1N1) in Pennsylvania public schools.

PubMed

Miller, Jeffrey R; Short, Vanessa L; Wu, Henry M; Waller, Kirsten; Mead, Paul; Kahn, Emily; Bahn, Beth A; Dale, Jon W; Nasrullah, Muazzam; Walton, Sabrina E; Urdaneta, Veronica; Ostroff, Stephen; Averhoff, Francisco

2013-04-01

School-based recommendations for nonpharmaceutical interventions (NPIs) were issued in response to the threat of 2009 pandemic influenza A (pH1N1). The implementation and effectiveness of these recommendations has not been assessed. In November 2009, a Web-based survey of all Pennsylvania public schools was conducted to assess the use of recommended NPIs. Overall, 1040 (31%) of 3351 schools participated in the survey. By fall 2009, 820 (84%) of 979 respondents reported that their school had an influenza plan in place, a 44% higher proportion than in the spring 2009 (p < .01). Most schools communicated health messages (eg, staying home when sick), implemented return to school requirements, and made hand sanitizer available. Schools with a spring influenza plan (N = 568) were less likely to report substantial influenza-like illness (ILI) during the fall wave of influenza than the 299 schools without a spring influenza plan (63% vs 71%, p = .02). This association persisted after controlling for schools with substantial ILI in the spring. The reported use of NPIs in participating Pennsylvania public schools improved substantially from spring to fall and was generally consistent with issued recommendations. The proactive implementation of a number of NPIs and the early implementation of communication and education initiatives might have cumulatively reduced the impact of pH1N1 in some schools. Published 2013. This article is a U.S. Government work and is in the public domain in the USA.

The Feasibility of Using Hydrogen Peroxide Decomposition Studies for High School Chemistry.

ERIC Educational Resources Information Center

Carter, Gillian E.

1986-01-01

Highlights difficulties that occur when teachers attempt to devise new experiments (use of hydrogen peroxide decomposition) and how seemingly useless results can be turned into productive student projects. Considers effects of ions present in tap water, pH, dust, and nature of vessel's surface. Reaction order and safety precautions are noted. (JN)

Research Productivity of LIS Schools in Pakistan: A Study of MPhil and PhD Theses to 2015

ERIC Educational Resources Information Center

Sheikh, Arslan; Jan, Saeed Ullah

2017-01-01

This article aims to present a comprehensive review of MPhil and PhD research theses produced by library and information science (LIS) schools in Pakistan from their beginning to 2015. It also explores the research trends in LIS, identifies gaps, and presents an agenda for future research by LIS scholars. The origin, development, and current…

The pH Game.

ERIC Educational Resources Information Center

Chemecology, 1996

1996-01-01

Describes a game that can be used to teach students about the acidity of liquids and substances around their school and enable them to understand what pH levels tell us about the environment. Students collect samples and measure the pH of water, soil, plants, and other natural material. (DDR)

Perspective: PhD scientists completing medical school in two years: looking at the Miami PhD-to-MD program alumni twenty years later.

PubMed

Koniaris, Leonidas G; Cheung, Michael C; Garrison, Gwen; Awad, William M; Zimmers, Teresa A

2010-04-01

Producing and retaining physician-scientists remains a major challenge in advancing innovation, knowledge, and patient care across all medical disciplines. Various programs during medical school, including MD-PhD programs, have been instituted to address the need for continued production of physician-scientists. From 1971 through 1989, 508 students with a prior PhD in the sciences, mathematics, or engineering graduated in two years from an accelerated MD program at the University of Miami School of Medicine. The program, designed to address potential clinical physician shortages rather than physician-scientist shortages, quickly attracted many top-notch scientists to medicine. Many program graduates went to top-tier residencies, pursued research careers in academic medicine, and became academic leaders in their respective fields. A retrospective examination of graduates conducted in 2008-2009 demonstrated that approximately 59% took positions in academic university medical departments, 3% worked for governmental agencies, 5% entered industry as researchers or executives, and 33% opted for private practice. Graduates' positions included 85 full professors, 11 university directors or division heads, 14 academic chairs, 2 medical school deans, and 1 astronaut. Overall, 30% of graduates had obtained National Institutes of Health funding after completing the program. These results suggest that accelerated medical training for accomplished scientists can produce a large number of successful physician-scientists and other leaders in medicine. Furthermore, these results suggest that shortening the medical portion of combined MD-PhD programs might also be considered.

A Road Less Traveled: An Editorial Career

NASA Astrophysics Data System (ADS)

Antonoyiannakis, Manolis

2008-03-01

It has been said that no life is completed the way one had planned for it, and mine is no exception to that rule so far. When I was graduating with a BSc I was convinced I'd be doing physics research for the rest of my life -- and when I was getting my PhD I was sure I'd be teaching high school physics and helping others learn for the foreseeable future. Yet, 9 years later, I am not doing either of these as a full time job, and I've changed my mind a couple more times as to what career path (and broader lifestyle) would work best for me. In the intervening years, I've learnt to embrace change as a tool for carving my own path, and to be wary of the certainties that can tie oneself to a ``safe'' but uninspiring future. I studied at the University of Thessaloniki, Greece, and at Royal Holloway University of London (BSc); also at the University of Illinois at Urbana-Champaign (MSc) and at Imperial College London (PhD). After my PhD (and the national military service in Greece), I taught at high-school level for a couple of years in Crete, Greece. At the same time, I was science editor for Crete University Press, Greece's major university press. From there, I jumped onto the APS editorial boat: First to PRB (2003), then to PRL (2007), where I am now an Assistant Editor. I also have an adjunct research position at Columbia University.

Implementation of an Education-Focused PhD Program in Anatomy and Cell Biology at Indiana University: Lessons Learned and Future Challenges

ERIC Educational Resources Information Center

Brokaw, James J.; O'Loughlin, Valerie D.

2015-01-01

In 2008, the Indiana University School of Medicine, in collaboration with the School of Education, admitted its first student to a newly approved PhD program in Anatomy and Cell Biology focusing on educational research rather than biomedical research. The goal of the program is twofold: (1) to provide students with extensive training in all of the…

Black Graduate and Professional School Enrollment: A Struggle for Equality

ERIC Educational Resources Information Center

Brown, Frank; Stent, Madelon D.

1975-01-01

The stated purpose of this paper is to provide a comprehensive picture of blacks enrolled in graduate and professional schools, and to present data on earned degrees; it is noted that a Ford Foundation sponsored study revealed that, by June 1969, 2,280 black men and women were holders of the Ph.D., i.e. less than one per cent of all Ph.D. holders.…

The Importance of Having a Ph.D., Career Advice

USDA-ARS?s Scientific Manuscript database

A presentation on the importance of having a PhD to motivate Initiative to Maximize Student Diversity Program (IMSD) undergrads towards conducting research, pursuing careers in the biomedical field, applying to grad school, and getting a Ph.D., based upon ARS scientist's experiences as a student, a ...

Cummings/Ju - Harvard; Emory | Division of Cancer Prevention

Cancer.gov

Principal Investigator: Richard D Cummings, PhDInstitution: Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA Principal Investigator: Tongzhong Ju, MD, PhDInstitution: Emory University, Atlanta, GA |

Effective School Leaders. Q&A with Eric A. Hanushek, Ph.D. REL Mid-Atlantic Teacher Effectiveness Webinar Series

ERIC Educational Resources Information Center

Regional Educational Laboratory Mid-Atlantic, 2014

2014-01-01

This webinar on effective school leaders discussed the important relationship between a school's socio-economic status, school leadership, and teacher turnover rate. Participants explored the major role of school leaders in fostering teacher effectiveness and discussed strategies they can use at the local level to increase school leader…

An Outbreak of 2009 Pandemic Influenza A (H1N1) Virus Infection in an Elementary School in Pennsylvania

PubMed Central

Bhattarai, Achuyt; Fagan, Ryan P.; Ostroff, Stephen; Sodha, Samir V.; Moll, Mària E.; Lee, Bruce Y.; Chang, Chung-Chou H.; Ennis, Brent; Britz, Phyllis; Fiore, Anthony; Nguyen, Michael; Palekar, Rakhee; Archer, W. Roodly; Gift, Thomas L.; Leap, Rebecca; Nygren, Benjamin L.; Cauchemez, Simon; Angulo, Frederick J.; Swerdlow, David

2011-01-01

In May 2009, one of the earliest outbreaks of 2009 pandemic influenza A virus (pH1N1) infection resulted in the closure of a semi-rural Pennsylvania elementary school. Two sequential telephone surveys were administered to 1345 students (85% of the students enrolled in the school) and household members in 313 households to collect data on influenza-like illness (ILI). A total of 167 persons (12.4%) among those in the surveyed households, including 93 (24.0%) of the School A students, reported ILI. Students were 3.1 times more likely than were other household members to develop ILI (95% confidence interval [CI], 2.3–4.1). Fourth-grade students were more likely to be affected than were students in other grades (relative risk, 2.2; 95% CI, 1.2–3.9). pH1N1 was confirmed in 26 (72.2%) of the individuals tested by real-time reverse-transcriptase polymerase chain reaction. The outbreak did not resume upon the reopening of the school after the 7-day closure. This investigation found that pH1N1 outbreaks at schools can have substantial attack rates; however, grades and classrooms are affected variably. Additioanl study is warranted to determine the effectiveness of school closure during outbreaks. PMID:21342888

A Colorimetric Analysis Experiment Not Requiring a Spectrophotometer: Quantitative Determination of Albumin in Powdered Egg White

ERIC Educational Resources Information Center

Charlton, Amanda K.; Sevcik, Richard S.; Tucker, Dorie A.; Schultz, Linda D.

2007-01-01

A general science experiment for high school chemistry students might serve as an excellent review of the concepts of solution preparation, solubility, pH, and qualitative and quantitative analysis of a common food product. The students could learn to use safe laboratory techniques, collect and analyze data using proper scientific methodology and…

Obituary: Frank Albini, 1936-2005

Treesearch

Pat Andrews

2006-01-01

Frank Albini, fire behavior research scientist from 1973 to 1985, died of cancer at the age of 69 on 3 December 2005. He was born in Madera, California, where he graduated from high school. He attended the California Institute of Technology and earned a BS in Aeronautical Engineering in 1958, and a year later an MS in Mechanical Engineering. He was awarded a PhD in...

2010 NRL Review: Power, Energy, Synergy

DTIC Science & Technology

2010-01-01

scientific, technical, engineering, and mathematics (STEM) fields. To this end, NRL has brought 399 students on board as employees, tutored another...Employees — Recent Ph.D., Faculty Member, and College Graduate Programs, Professional Appointments, and College and High School Student Programs 278...information with higher-level cognitive reasoning; gesture recognition for shoulder-to- shoulder human-robot interaction; and anticipation and learning on a

The Doctorate in Education. Volume IV, Follow-UP Study.

ERIC Educational Resources Information Center

Ludlow, H. Glenn; And Others

A study was conducted (follow-up to SP 004 600) of the 1,186 recipients of the Ed.D. and Ph.D. degrees in education in the United States in 1958. Questionnaire data was collected to investigate 5-year career development and job satisfaction plus ability and achievement (as measured by high school graduating class rank, intelligence test scores,…

Acoustic Studies of New Materials: Quasicrystals, Low-Loss Glasses, and High Tc Superconductors

DTIC Science & Technology

1991-12-18

Progress Report, 1989 2. Tania Slawecki, M.S. Thesis Measuring fourth sound in silica aerogel 3. Chang Yu, Ph.D. Thesis A high Q resonant photoacoustic...Pennsylvania State University The Graduate School Department of Physics Measuring Fourth Sound in Silica Aerogel A Thesis in Physics by Tania Maria...Slawecki Submitted in Partial Fulfillment of the Requirements for the Degree of Master of Science December 1989 Abstract Measuring Fourth Sound in Silica

Implementing a Workforce Development Pipeline

NASA Technical Reports Server (NTRS)

Hix, Billy

2002-01-01

Research shows that the number of highly trained scientists and engineers has continued a steady decline during the 1990's. Furthermore, at the high school level, almost 40% of the total high school graduates are seeking technical skills in preparation of entering the workforce directly. The decrease of students in technology and science programs, along with the lack of viable vocational programs, haunts educators and businesses alike. However, MSFC (Marshall Space Flight Center) has the opportunity to become a leading edge model of workforce development by offering a unified program of apprenticeships, workshops, and educational initiatives. These programs will be designed to encourage young people of all backgrounds to pursue the fields of technology and science, to assist research opportunities, and to support teachers in the systemic changes that they are facing. The emphasis of our program based on grade levels will be: Elementary Level: Exposure to the workforce. Middle School: Examine the workforce. High School and beyond: Instruct the workforce. It is proposed that MSFC create a well-integrated Workforce Development Pipeline Program. The program will act to integrate the many and varied programs offered across MSFC directorates and offices. It will offer a clear path of programs for students throughout middle school, high school, technical training, and college and universities. The end result would consist of technicians, bachelors degrees, masters degrees, and PhDs in science and engineering fields entering the nation's workforce, with a focus on NASA's future personnel needs.

Breath acidification in adolescent runners exposed to atmospheric pollution: A prospective, repeated measures observational study

PubMed Central

Ferdinands, Jill M; Crawford, Carol A Gotway; Greenwald, Roby; Van Sickle, David; Hunter, Eric; Teague, W Gerald

2008-01-01

Background Vigorous outdoors exercise during an episode of air pollution might cause airway inflammation. The purpose of this study was to examine the effects of vigorous outdoor exercise during peak smog season on breath pH, a biomarker of airway inflammation, in adolescent athletes. Methods We measured breath pH both pre- and post-exercise on ten days during peak smog season in 16 high school athletes engaged in daily long-distance running in a downwind suburb of Atlanta. The association of post-exercise breath pH with ambient ozone and particulate matter concentrations was tested with linear regression. Results We collected 144 pre-exercise and 146 post-exercise breath samples from 16 runners (mean age 14.9 years, 56% male). Median pre-exercise breath pH was 7.58 (interquartile range: 6.90 to 7.86) and did not change significantly after exercise. We observed no significant association between ambient ozone or particulate matter and post-exercise breath pH. However both pre- and post-exercise breath pH were strikingly low in these athletes when compared to a control sample of 14 relatively sedentary healthy adults and to published values of breath pH in healthy subjects. Conclusion Although we did not observe an acute effect of air pollution exposure during exercise on breath pH, breath pH was surprisingly low in this sample of otherwise healthy long-distance runners. We speculate that repetitive vigorous exercise may induce airway acidification. PMID:18328105

Good Mental Health

MedlinePlus

... Lumley, Ph.D., Professor and Director of Clinical Psychology Training, Department of Psychology, Wayne State University, and his Stress and Health ... Jennifer J. Thomas, Ph.D., Associate Professors of Psychology, Department of Psychiatry, Harvard Medical School; Co-Directors ...

Body Image

MedlinePlus

... Lumley, Ph.D., Professor and Director of Clinical Psychology Training, Department of Psychology, Wayne State University, and his Stress and Health ... Jennifer J. Thomas, Ph.D., Associate Professors of Psychology, Department of Psychiatry, Harvard Medical School; Co-Directors ...

Specific Phobias

MedlinePlus

... Lumley, Ph.D., Professor and Director of Clinical Psychology Training, Department of Psychology, Wayne State University, and his Stress and Health ... Jennifer J. Thomas, Ph.D., Associate Professors of Psychology, Department of Psychiatry, Harvard Medical School; Co-Directors ...

Cosmetic Surgery

MedlinePlus

... Lumley, Ph.D., Professor and Director of Clinical Psychology Training, Department of Psychology, Wayne State University, and his Stress and Health ... Jennifer J. Thomas, Ph.D., Associate Professors of Psychology, Department of Psychiatry, Harvard Medical School; Co-Directors ...

Science, Engineering, and Mathematics (SEM) at the Timbuktu Academy

DTIC Science & Technology

2005-07-31

School @ CalTech (PhD Chemistry Program) Millican , Jasmine F Su02 ONR 20 Fall `02- Grad . School @ LSU for Ph .D. in Chemistry, Baton Rouge, LA Thomas...n 22 . Joshua McKinsey Stennis Space Center - Stennis Space Center, M S 23 . Jasmine Millican Louisiana State University (LAMP Program) - Baton Rouge...OH 26. Rachel Mckinsey Fr ./Physics MIT- Boston, M A 27. Jasmine Millican Jr ./Chemistry University of Illinois - Chicago, I L 28. Symoane Mizell So

76 FR 6405 - Marine Mammals; File No. 15654

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-04

... Church, PhD, Professor of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115...-02 issued to John Wise, PhD) and maintained at Harvard University for the proposed study. Cell lines...

75 FR 31788 - Appointments to the Medicare Payment Advisory Commission (MedPAC)

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-04

..., Group Health Cooperative; Katherine Baicker, PhD, Professor of Health Economics, Department of Health Policy and Management, Harvard School of Public Health; Mary Naylor, PhD, RN, FAAN, Professor of...

Panic Disorder and Women

MedlinePlus

... Lumley, Ph.D., Professor and Director of Clinical Psychology Training, Department of Psychology, Wayne State University, and his Stress and Health ... Jennifer J. Thomas, Ph.D., Associate Professors of Psychology, Department of Psychiatry, Harvard Medical School; Co-Directors ...

75 FR 55738 - Marine Mammals; File No. 15654

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-14

... George Church, Ph.D. (Applicant), Professor of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur... (Permit No. 1008-1637-02 issued to John Wise, Ph.D.) and maintained at Harvard University for the proposed...

Engaging Students in the Pacific and beyond Using an Inquiry-Based Lesson in Ocean Acidification

ERIC Educational Resources Information Center

Gorospe, Kelvin D.; Fox, Bradley K.; Haverkort-Yeh, Roxanne D.; Tamaru, Clyde S.; Rivera, Malia Ana J.

2013-01-01

We present a hands-on, inquiry-based activity exploring how CO[subscript 2] input to seawater affects the skeletons of several species of reef-building corals and other marine organisms by testing for changes in pH and calcium ion concentrations. Originally developed to inspire and recruit high school students in the state of Hawai'i into the…

pH [Measure of Acidity].

ERIC Educational Resources Information Center

Henderson, Paula

This autoinstructional program deals with the study of the pH of given substances by using litmus and hydrion papers. It is a learning activity directed toward low achievers involved in the study of biology at the secondary school level. The time suggested for the unit is 25-30 minutes (plus additional time for further pH testing). The equipment…

What if We Made Fewer Ph.D.'s?

ERIC Educational Resources Information Center

Cassuto, Leonard

2012-01-01

Whenever a discussion opens about nonacademic employment for Ph.D.s, it is not long before someone suggests reducing graduate-school admissions. "The market for full-time scholars has fallen off a cliff lately," this argument goes, "so why not just train fewer of them?" The strategy to reduce the number of Ph.D. students recurs in those…

Women in Physics in Canada

NASA Astrophysics Data System (ADS)

McKenna, Janis

2012-10-01

Here we are in the 21st century in Canada, where most of us would say that young girls and boys have equal access to education, opportunities, and careers of their own choice. In Canada, women currently outnumber men in full-time university enrollment, in Medical Schools and in Law Schools. 48% of the Canadian work force is female, yet women make up only 21% of working professionals in science, engineering and technology. Canada-wide in Physics, the situation is such that only 20% of our BSc graduates are women, and 19% of our PhD graduates are women. It is evident that the ``leaky pipeline'' in Physics leaks most at a young age, before BSc graduation. High school physics statistics in BC indicate that while most of the grade 12 science and math disciplines have roughly equal numbers of young men and women enrolled, this is not the case for high school physics, where province-wide, only 30% of Physics 12 students are women. (Biology is also skewed, but in the other direction: 62% of Biology 12 students are women) This poster will present current statistics and will hopefully be a wake-up call for us all to consider participating in more outreach in science, and especially physics, in our high schools.

Acoustic Rapid COTS Insertion: A Case Study in Spiral Development

DTIC Science & Technology

2006-10-30

Provost The Acquisition Chair, Graduate School of Business & Public Policy, Naval Postgraduate School supported the funding of the research...Senior Lecturer Graduate School of Business & Public Policy Reviewed by: ________________________________ Robert N. Beck Dean, Graduate...School of Business & Public Policy Released by: ________________________________ Dan C. Boger, Ph.D. Acting Dean of Research

ROLE OF INSTITUTIONAL CLIMATE IN FOSTERING DIVERSITY IN BIOMEDICAL RESEARCH WORKFORCE: A CASE STUDY

PubMed Central

Butts, Gary C.; Hurd, Yasmin; Palermo, Ann-Gel S.; Delbrune, Denise; Saran, Suman; Zony, Chati; Krulwich, Terry A.

2012-01-01

This article reviews the barriers to diversity in biomedical research, describes the evolution and efforts to address climate issues to enhance the ability to attract, retain and develop underrepresented minorities (URM) - underrepresented minorities whose underrepresentation is found both in science and medicine, in the graduate school biomedical research doctoral programs (PhD and MD/PhD) at Mount Sinai School of Medicine (MSSM). We also describe the potential beneficial impact of having a climate that supports diversity and inclusion in the biomedical research workforce. MSSM diversity climate efforts are discussed as part of a comprehensive plan to increase diversity in all institutional programs PhD, MD/PhD, MD, and at the residency, post doctoral fellow, and faculty levels. Lessons learned from four decades of targeted programs and activities at MSSM may be of value to other institutions interested in improving diversity in the biomedical science and academic medicine workforce. PMID:22786740

Biomedical PhD education--an international perspective.

PubMed

Mulvany, Michael J

2013-05-01

The PhD, otherwise known as the doctor of philosophy or Dr. Phil., is an internationally recognized degree, indicating that the PhD graduate has received training in research under supervision. Traditionally, the PhD was the route to an academic career, with most successful PhD graduates receiving tenured university positions. However, over the past 20-30 years, and particularly the past 10 years, the situation has changed dramatically. Governments in many countries have invested massively in PhD education, believing that trained researchers will contribute to the 'knowledge society', and thus increase the competitiveness of their countries in the future economies of the world. Thus, only a small fraction of PhD graduates now end up in academic research. Yet, the PhD remains a research degree, and indeed, institutions have become heavily dependent on PhD students for their research output. The situation has thus created a paradox. On the one hand, it has become essential for institutions to have many PhD students and for the research performed to be of the highest level. On the other hand, the careers of PhD students are not necessarily going to be directly related to the research performed during their PhD studies. The purpose of this article is to explore how this seeming paradox is being addressed in biomedicine and to show that far from being inconsistent that the two aspects are in fact complementary. The article is based on the author's experience as Head of Aarhus Graduate School of Health Sciences 2002-2011 and his work with graduate schools across Europe and internationally through the organization ORPHEUS. © 2013 Nordic Pharmacological Society. Published by Blackwell Publishing Ltd.

Validity of the Medical College Admission Test for predicting MD-PhD student outcomes.

PubMed

Bills, James L; VanHouten, Jacob; Grundy, Michelle M; Chalkley, Roger; Dermody, Terence S

2016-03-01

The Medical College Admission Test (MCAT) is a quantitative metric used by MD and MD-PhD programs to evaluate applicants for admission. This study assessed the validity of the MCAT in predicting training performance measures and career outcomes for MD-PhD students at a single institution. The study population consisted of 153 graduates of the Vanderbilt Medical Scientist Training Program (combined MD-PhD program) who matriculated between 1963 and 2003 and completed dual-degree training. This population was divided into three cohorts corresponding to the version of the MCAT taken at the time of application. Multivariable regression (logistic for binary outcomes and linear for continuous outcomes) was used to analyze factors associated with outcome measures. The MCAT score and undergraduate GPA (uGPA) were treated as independent variables; medical and graduate school grades, time-to-PhD defense, USMLE scores, publication number, and career outcome were dependent variables. For cohort 1 (1963-1977), MCAT score was not associated with any assessed outcome, although uGPA was associated with medical school preclinical GPA and graduate school GPA (gsGPA). For cohort 2 (1978-1991), MCAT score was associated with USMLE Step II score and inversely correlated with publication number, and uGPA was associated with preclinical GPA (mspGPA) and clinical GPA (mscGPA). For cohort 3 (1992-2003), the MCAT score was associated with mscGPA, and uGPA was associated with gsGPA. Overall, MCAT score and uGPA were inconsistent or weak predictors of training metrics and career outcomes for this population of MD-PhD students.

TEACHER TRAINING: How to Produce Better Math and Science Teachers.

PubMed

Mervis, J

2000-09-01

Two National Research Council panels have released new reports on improving science and math education in the United States. One panel says that the best way to improve teacher education is to make it a continuum, with school districts taking more responsibility for the initial preparation of new teachers and university faculty playing a bigger role in ongoing professional development. The other panel says that more recent science Ph.D.s would be willing to teach high school science and math if the government helped with the transition, if the certification process were compressed, and if they could retain ties to research.

Teaching Ph.D.'s How to Reach Out

ERIC Educational Resources Information Center

Cassuto, Leonard

2012-01-01

Marc Aronson, a lecturer in the School of Communication and Information at Rutgers University at New Brunswick and a historian who writes books for young adults, recently suggested that all Ph.D. candidates be required to take a course he calls "Communications." The goal would be to teach Ph.D.'s--both would-be academics and those who will pursue…

Challenges of PhD Graduated Nurses for Role Acceptance as a Clinical Educator: A Qualitative Study.

PubMed

Haghighi Moghadam, Yousef; Atashzadeh-Shoorideh, Foroozan; Abbaszadeh, Abbas; Feizi, Aram

2017-06-01

Introduction: Clinical education is the core component of nursing education. PhD graduated nurses who are faculty members can play a main role in clinical instruction. However, there is not clear understanding about the challenges which they may encounter for accepting their role as clinical educator. The aim of this study was to explore the challenges of role acceptance by PhD aduated nurses who are faculty members. Methods: In this qualitative exploratory study a total of 13 participants (8 PhD graduated in nursing, 3 head of departments of nursing, one educational vice chancellor of nursing school, and one nurse) were selected by purposive sampling method. Data were collected by semi-structured, face to face interview and analyzed by conventional content analysis approach developed by Graneheim and Lundman. Results: The main theme emerged from data analysis was "identity threat". This theme had five categories including expectations beyond ability, lack of staff's rely on the performance of PhD graduated nurses, poor clinical competencies, doubtfulness, and obligation. Conclusion: PhD graduated nurses experienced some worries about their role as clinical educators and argued that they have not been prepared for their role. Therefore, policy makers and authorities of nursing schools should support PhD graduated nurses for accepting their new roles as clinical educators. Moreover, some changes in nursing PhD curriculum is needed to improve the clinical competencies of PhD graduated and prepare them for their role as a clinical educator.

Challenges of PhD Graduated Nurses for Role Acceptance as a Clinical Educator: A Qualitative Study

PubMed Central

Haghighi Moghadam, Yousef; Atashzadeh-Shoorideh, Foroozan; Abbaszadeh, Abbas; Feizi, Aram

2017-01-01

Introduction: Clinical education is the core component of nursing education. PhD graduated nurses who are faculty members can play a main role in clinical instruction. However, there is not clear understanding about the challenges which they may encounter for accepting their role as clinical educator. The aim of this study was to explore the challenges of role acceptance by PhD aduated nurses who are faculty members. Methods: In this qualitative exploratory study a total of 13 participants (8 PhD graduated in nursing, 3 head of departments of nursing, one educational vice chancellor of nursing school, and one nurse) were selected by purposive sampling method. Data were collected by semi-structured, face to face interview and analyzed by conventional content analysis approach developed by Graneheim and Lundman. Results: The main theme emerged from data analysis was "identity threat". This theme had five categories including expectations beyond ability, lack of staff’s rely on the performance of PhD graduated nurses, poor clinical competencies, doubtfulness, and obligation. Conclusion: PhD graduated nurses experienced some worries about their role as clinical educators and argued that they have not been prepared for their role. Therefore, policy makers and authorities of nursing schools should support PhD graduated nurses for accepting their new roles as clinical educators. Moreover, some changes in nursing PhD curriculum is needed to improve the clinical competencies of PhD graduated and prepare them for their role as a clinical educator. PMID:28680869

75 FR 6184 - Endangered Species; File No. 14754

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-08

... Isaac Wirgin, PhD, New York University School of Medicine, Department of Environmental Medicine, Tuxedo... Dr. Isaac Wirgin of the New York University School of Medicine, Department of Environmental Medicine...

Where Are They Now: Janine Bahsali’s Journey from Researcher to Counselor and Beyond | Poster

Cancer.gov

Former Werner H. Kirsten (WHK) intern Janine Bahsali, who will be attending Adler University this fall to pursue a doctorate in clinical psychology, credits her internships at NCI at Frederick with starting her down the path toward a Ph.D. Bahsali joined the WHK Student Intern Program during her senior year of high school, working in Occupational Health Services with mentor

A proposal to establish master's in biomedical sciences degree programs in medical school environments.

PubMed

Ingoglia, Nicholas A

2009-04-01

Most graduate schools associated with medical schools offer programs leading to the PhD degree but pay little attention to master's programs. This is unfortunate because many university graduates who are interested specifically in biomedical rather than pure science fields need further education before making decisions on whether to enter clinical, research, education, or business careers. Training for these students is done best in a medical school, rather than a graduate university, environment and by faculty who are engaged in research in the biomedical sciences. Students benefit from these programs by exploring career options they might not have previously considered while learning about disease-related subjects at the graduate level. Graduate faculty can also benefit by being compensated for their teaching with a portion of the tuition revenue, funds that can help run their laboratories and support other academic expenses. Faculty also may attract talented students to their labs and to their PhD programs by exposing them to a passion for research. The graduate school also benefits by collecting masters tuition revenue that can be used toward supporting PhD stipends. Six-year outcome data from the program at Newark show that, on completion of the program, most students enter educational, clinical, or research careers and that the graduate school has established a new and significant stream of revenue. Thus, the establishment of a master's program in biomedical sciences that helps students match their academic abilities with their career goals significantly benefits students as well as the graduate school and its faculty.

David Hurlbut | NREL

Science.gov Websites

Education Ph.D. in public policy, Lyndon B. Johnson School of Public Affairs, the University of Texas at Austin, 1999 Master of public affairs, Lyndon B. Johnson School of Public Affairs, the University of

Relationship Between Time of First Publication and Subsequent Publication Success Among Non-PhD Physician-Scientists.

PubMed

Riggs, Kevin R; Reitman, Zachary J; Mielenz, Thelma J; Goodman, Philip C

2012-06-01

Studies have shown that publication of work during medical school and residency is associated with higher numbers of later publications and citations of published research. However, it is unknown whether this association exists for non-PhD physician-scientists and whether the association persists later into their careers. We extracted publication records from the curricula vitae (CVs) of 102 corresponding authors of articles published in 2008 in the New England Journal of Medicine and JAMA, and obtained those authors' citation records from Web of Science. We used regression models to examine the association between time of first publication and later publication and citation rates for the entire postgraduate career and a recent 2-year period. After adjusting for time since medical school graduation, sex, location of medical school (United States or not United States), and additional non-PhD degrees, we found that authors who first published before graduating from medical school had a greater mean number of publications after medical school and during the period from 2006 to 2007 (164 and 28, respectively) than those who first published during the 5 years afterward (111 and 19, respectively) and those who first published more than 5 years after graduation (59 and 13, respectively). Similarly, authors who first published before graduating from medical school had a greater mean number of citations of their published work since graduation and of publications from 2006 to 2007 (4634 and 333, respectively) than those who first published during the 5 years afterward (2936 and 183, respectively) and those who first published more than 5 years after graduation (1512 and 143, respectively). Early publication is associated with higher numbers of publications and more citations of published research among non-PhD physician-scientists. This association persists well into a researcher's career.

Educator Effectiveness Series: Assessing School Climate. Q&A with Jonathan Cohen, Ph.D. REL Mid-Atlantic Webinar

ERIC Educational Resources Information Center

Cohen, Jonathan

2015-01-01

The REL Mid-Atlantic Webinar discussed the elements in a positive school climate and shared different methods for assessing school data, including the Comprehensive School Climate Inventory. The Q&A presented in this document address the questions participants had for Dr. Cohen following the webinar. The webinar recording and PowerPoint…

A validation study of public health knowledge, skills, social responsibility and applied learning.

PubMed

Vackova, Dana; Chen, Coco K; Lui, Juliana N M; Johnston, Janice M

2018-06-22

To design and validate a questionnaire to measure medical students' Public Health (PH) knowledge, skills, social responsibility and applied learning as indicated in the four domains recommended by the Association of Schools & Programmes of Public Health (ASPPH). A cross-sectional study was conducted to develop an evaluation tool for PH undergraduate education through item generation, reduction, refinement and validation. The 74 preliminary items derived from the existing literature were reduced to 55 items based on expert panel review which included those with expertise in PH, psychometrics and medical education, as well as medical students. Psychometric properties of the preliminary questionnaire were assessed as follows: frequency of endorsement for item variance; principal component analysis (PCA) with varimax rotation for item reduction and factor estimation; Cronbach's Alpha, item-total correlation and test-retest validity for internal consistency and reliability. PCA yielded five factors: PH Learning Experience (6 items); PH Risk Assessment and Communication (5 items); Future Use of Evidence in Practice (6 items); Recognition of PH as a Scientific Discipline (4 items); and PH Skills Development (3 items), explaining 72.05% variance. Internal consistency and reliability tests were satisfactory (Cronbach's Alpha ranged from 0.87 to 0.90; item-total correlation > 0.59). Lower paired test-retest correlations reflected instability in a social science environment. An evaluation tool for community-centred PH education has been developed and validated. The tool measures PH knowledge, skills, social responsibilities and applied learning as recommended by the internationally recognised Association of Schools & Programmes of Public Health (ASPPH).

A Profile of Chemistry Degree Holders in Academic Jobs

ERIC Educational Resources Information Center

Robinson, G. W.

1973-01-01

Presents statistical data on the distribution of institutions' Bachelor and Ph.D. chemistry graduates in faculty positions at research oriented schools with a comparison between the institutions' Ph.D. degree rankings and the rankings given by the American Council on Education included. (CC)

Optimal Semi-Adaptive Search With False Targets

DTIC Science & Technology

2017-12-01

we do not execute a full experimental design to attempt to build a response surface for the performance of these model under various combinations of...the degree of MASTER OF SCIENCE IN OPERATIONS RESEARCH from the NAVAL POSTGRADUATE SCHOOL December 2017 Approved by: Johannes O. Royset, Ph.D. Thesis...Advisor Dashi I. Singham, Ph.D. Second Reader Patricia A. Jacobs, Ph.D. Chair, Department of Operations Research iii THIS PAGE INTENTIONALLY LEFT

A stepwise procedure for science communication in the field

NASA Astrophysics Data System (ADS)

Nisancioglu, Kerim; Paasche, Øyvind

2017-04-01

Communicating and disseminating earth science to laypersons, high-school students and their teachers are becoming increasingly important considering the overwhelming impact human civilization have on the planet. One of the main challenges with this type of dissemination arises from the cross-disciplinary nature of the Earth system as it encompasses anything from cloud physics to the geological evidence of ice ages being played out on millennial time scales. During the last four years we have tested and developed an approach referred to as «Turspor» which can be translated to 'Trail Tracks'. The ambition with "Turspor" is to inspire participants to seek in-depth knowledge relating to observations of features made in the field (glacial moraines, active permafrost, clouds, winds and so forth) as we have come to learn that observations made in the field enhances students capability to grasp the bare essentials related to the phenomena in question. By engaging master and PhD students in the process we create a platform where students can improve their teaching and communicative skills through a stepwise procedure. The initial concept was tested on 35 high school students during the summer of 2012 in the mountainous area of Snøheim on Dovre, Southern Norway. Before the arrival of the high school students, the university students prepared one page written summaries describing relevant geological or meteorological features and trained on how to best disseminate a basic scientific understanding of these. Specific examples were patterned ground caused by permafrost, glacier flour, katabatic winds, and equilibrium line altitude of glaciers. Based on the success of the program over the past 4 years with field trips together with local schools, we are in the process of developing the concept to be offered as a course at the master and PhD level, including a week of training in didactics applied to topics in the geosciences as well as practical training in the field. The university students who complete the course will be in charge of guiding local high school students in the field (mostly at university field stations in the mountains of Norway), as well as follow up on the topics discussed in collaboration with the high-school teachers during a subsequent visit to the classroom. By participating in the program, high-school students will experience inquiry-based learning, adding to their understanding of the scientific process. Sites developed through this program so far have been documented with a GPS tag, detailed description, background and pictures and hosted by the Norwegian Trekking Association website: ut.no as well as an associated app. The stepwise procedure of this concept has been developed through continous interaction with teachers, students and the general public. As a consequence, our capability to address and explain many earth science features of large societal relevance such as glacier retreat, thawing permafrost, flooding, snow avalanches, vegetation dynamics and climate change in general has been greatly improved. For examples see https://www.ut.no/gruppe/8.1819/

'The Right Time and the Right Place': An Interview with Jacques Miller.

PubMed

Anderson, Warwick

2016-01-01

Professor Jacques F.P. Miller spoke about his career in immunology with Warwick Anderson on 3 February 2014. Born in Nice, France, Miller attended high school and medical school in Sydney, Australia. As a Ph.D. student and postgraduate researcher in London, Miller discovered the immunological function of the thymus gland. Spending the rest of his career at the Walter and Eliza Hall Institute for Medical Research in Melbourne, Miller conducted pioneering research in lymphocyte population dynamics and the mechanisms of the human immune response. With Graham Mitchell, he demonstrated that mammalian lymphocytes can be divided into what became known as T cells and B cells, which interact to produce antibodies.

The Way to Win in Graduate School.

ERIC Educational Resources Information Center

Cortada, James W.; Winkler, Vera C.

Designed to help students who either want to go to American graduate schools or who are already in advanced degree programs, this book was written from the student's point of view. Chapter One on becoming a graduate student discusses motivation, choice of school, preparation for graduate work, graduate programs (the M.A. and PhD.), differences…

Performing international outreach: PhUn Week in an Australian primary school.

PubMed

Halpin, Patricia A

2017-03-01

Physiology Understanding (PhUn) Week is an annual science outreach program sponsored by the American Physiological Society in which K-12 students learn about physiology through meeting a physiologist and performing an experiment. Performing PhUn Week at an Australian private primary school during a family vacation in 2014 enabled me to receive a fellowship to return the following year for further implementation. To set up the outreach, I contacted the assistant principal of a public primary school, and she connected me with the physical education (PE) teacher. Together, the PE teacher and I planned the event. Over the course of 2 days, I taught eight classes, a total of 176 K-12 students. I started each lesson by explaining the role of a physiologist. The scientific method was described and explained. A hypothesis, "Exercise increases heart rate," was designed and tested. The students measured their heart rates, exercised, and measured their heart rates again. After data collection, results were reported, and the students all agreed that their hypothesis was supported. We then discussed heart function and why heart rate increases with exercise. The students then performed a pedometer challenge, where they estimated the number of steps during walking, running, and kangaroo hopping. They enjoyed testing their predictions and repeated these experiments several times. The students then made suggestions of ways they could continue this lesson outside of school. This first report of an international PhUn week confirmed that these events form partnerships among educators and inspire K-12 students to think about becoming scientists. Copyright © 2017 the American Physiological Society.

Pharmacological MRI (phMRI) of the Human Central Nervous System.

PubMed

Lanfermann, H; Schindler, C; Jordan, J; Krug, N; Raab, P

2015-10-01

Pharmacological magnetic resonance imaging (phMRI) of the central nervous system (CNS) addresses the increasing demands in the biopharma industry for new methods that can accurately predict, as early as possible, whether novel CNS agents will be effective and safe. Imaging of physiological and molecular-level function can provide a more direct measure of a drug mechanism of action, enabling more predictive measures of drug activity. The availability of phMRI of the nervous system within the professional infrastructure of the Clinical Research Center (CRC) Hannover as proof of concept center ensures that advances in basic science progress swiftly into benefits for patients. Advanced standardized MRI techniques including quantitative MRI, kurtosis determination, functional MRI, and spectroscopic imaging of the entire brain are necessary for phMRI. As a result, MR scanners will evolve into high-precision measuring instruments for assessment of desirable and undesirable effects of drugs as the basic precondition for individually tailored therapy. The CRC's Imaging Unit with high-end large-scale equipment will allow the following unique opportunities: for example, identification of MR-based biomarkers to assess the effect of drugs (surrogate parameters), establishment of normal levels and reference ranges for MRI-based biomarkers, evaluation of the most relevant MRI sequences for drug monitoring in outpatient care. Another very important prerequisite for phMRI is the MHH Core Facility as the scientific and operational study unit of the CRC partner Hannover Medical School. This unit is responsible for the study coordination, conduction, complete study logistics, administration, and application of the quality assurance system based on required industry standards.

pH modulation and salivary sugar clearance of different chocolates in children: A randomized clinical trial.

PubMed

Nirmala, Svsg; Quadar, Mohammed Akhil; Veluru, Sindhuri

2016-01-01

Sugars that occur naturally in foods and those added in processed foods may act as the source for fermentable carbohydrates and may initiate caries process. Among all the foods consumed by children, chocolates form an important constituent. A wide variety of chocolates are available in the Indian market and very few studies have compared their acidogenicity and salivary sugar clearance. To compare the acidogenicity and salivary sugar clearance of 6 different commercially available chocolates in the Indian market. Thirty subjects aged 10-15 years were selected randomly from one of the available public schools in Nellore city. Six commercially available chocolates in the Indian market were divided into three groups, unfilled (dark and milk chocolate), filled (wafer and fruit and nuts chocolate), and candy (hard milk and mango-flavored candy) groups. Plaque pH values and salivary sugar clearance rates are assessed at baseline, 5, 10, 15, 20, and 30 min after consumption. All the data obtained were statistically evaluated using independent sample t-test and one-way ANOVA for multiple group comparisons. Mango-flavored candy had maximum fall in plaque pH and least fall in plaque pH was recorded with milk chocolate. Fruit and nuts chocolate had a maximum clearance of salivary sugar and least fall in the salivary sugar clearance was recorded with dark chocolate. When the plaque pH and salivary sugar clearance of all the chocolates were assessed, it was seen that the values were statistically significant at all the time intervals (P < 0.05). Dark chocolate had a high fall in pH and milk chocolate had low salivary sugar clearance which signifies that unfilled chocolates are more cariogenic than other chocolates. Even though mango-flavored candy had maximum fall in plaque pH, its salivary sugar clearance was high.

Teresa Barnes, Ph.D. | NREL

Science.gov Websites

Engineering, Colorado School of Mines B.S. Chemical Engineering, University of Maryland Featured Publications studied plasma-assisted chemical vapor deposition chemistry and transparent conducting oxide growth as a exploring the fundamental limits of CdTe performance using molecular beam epitaxy. Education Ph.D. Chemical

77 FR 62245 - National Institute of General Medical Sciences Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-12

... Slice, Ph.D., Scientific Review Officer, David Geffen School of Medicine, University of California, Los... North, 6130 Executive Boulevard, Room H, Rockville, MD 20892. Contact Person: Arthur L. Zachary, Ph.D..., Cell Biology and Biophysics Research; 93.859, Pharmacology, Physiology, and Biological Chemistry...

Comparative evaluation of the effects of xylitol and sugar-free chewing gums on salivary and dental plaque pH in children.

PubMed

Kumar, Shikhar; Sogi, Suma H P; Indushekar, K R

2013-01-01

This research paper primarily focuses on the importance of use of xylitol among school children. The purpose of this paper is to evaluate the salivary and dental plaque pH changes after consumption of sugared and sugar-free (xylitol) chewing gums in children. A total of 30 school children were selected for this study and were divided into two equal groups and given both chewing gums for the experiment. Children consuming the sugar-free (xylitol) chewing gum showed a marked increase in the pH of saliva and plaque when compared to their counterpart. All these values had a significant difference of P ≤ 0.0001. Xylitol is a safe all-natural sweetener which helps to reduce tooth decay. It plays a unique role in preventive strategies for better health.

Effectiveness of Mouthrinse formulated from Aqueous Extract of Terminalia chebula on Salivary Streptococcus mutans Count and pH among 8- to 12-year-old School Children of Karnataka: A Randomized Clinical Trial.

PubMed

Palit, Madhuchanda; Hegde, Sundeep K; Bhat, Sham S

2016-01-01

The aim of the present study was to evaluate the anticar-iogenic efficacy of hot and cold aqueous extracts of Terminalia chebula against Streptococcus mutans as an oral rinse and also to discover the acceptability of the mouthwash in children. Sixty children between 8 and 12 years with high caries risk were selected. 10% concentration of hot and cold aqueous extracts were prepared. Children were randomly divided into extract and control group. Baseline salivary samples were taken, and the samples were re-collected at 10, 60, and 90 minutes interval after rinsing. Microbial and pH analysis were done. An acceptability questionnaire was filled. Tukey's multiple comparison test. The results show statistically significant difference in S. mutans counts at 10, 60, and 90 minutes interval when compared with negative control. However, when the hot and cold extracts were compared, there was no significant difference. Acceptability questionnaire showed 65 to 75% overall acceptability for both types of extract. Results of this study showed that both types of aqueous extract of T. chebula may be used as potential anticariogenic mouthwash with acceptable taste in children. Palit MC, Hegde SK, Bhat SS. Effectiveness of Mouthrinse formulated from Aqueous Extract of Terminalia chebula on Salivary Streptococcus mutans Count and pH among 8- to 12-year-old School Children of Karnataka: A Randomized Clinical Trial. Int J Clin Pediatr Dent 2016;9(4):349-354.

How One School Librarian Became an Author

ERIC Educational Resources Information Center

Kerby, Mona

2010-01-01

Back when the author was the school librarian at Little Elementary School in Arlington, Texas, she started writing and publishing books for children. She had completed her master's and PhD in Library Science from Texas Woman's University while working full time, and when she finally finished, she had such well-honed time management skills that she…

Negotiating a Research Protocol for Studying School-Based Gay and Lesbian Issues

ERIC Educational Resources Information Center

Donelson, Randal; Rogers, Theresa

2004-01-01

The nature of public schooling, particularly at the early and middle childhood levels, makes designing critical qualitative studies around gay and lesbian issues in the school context problematic at best. This article provides a retrospective dialogue between an associate professor and her then Ph.D. candidate advisee that reflects on the tension…

United States Air Force Summer Research Program -- 1993. Volume 1. Program Management Report

DTIC Science & Technology

1993-12-01

IEEE Spectrum and Physics Today. High school applicants can participate only in laboratories located no more than 20 miles from their residence. Tailored...faculty and $37/day for graduate students whose homes were more than 50 miles from the laboratory. Transportation to the laboratory at the beginning of...TX 78212- 7200 Branting, Luther Field: Dept of Computer Science Assistant Professor, PhD Laboratory: AL/HR PC Box 3682 University of Wyoming Vol-Page

Implementation of an education-focused PhD program in anatomy and cell biology at Indiana University: lessons learned and future challenges.

PubMed

Brokaw, James J; O'Loughlin, Valerie D

2015-01-01

In 2008, the Indiana University School of Medicine, in collaboration with the School of Education, admitted its first student to a newly approved PhD program in Anatomy and Cell Biology focusing on educational research rather than biomedical research. The goal of the program is twofold: (1) to provide students with extensive training in all of the anatomical disciplines coupled with sufficient teaching experience to assume major educational responsibilities upon graduation and (2) to train students to conduct rigorous medical education research and other scholarly work necessary for promotion and tenure. The 90 credit hour curriculum consists of biomedical courses taught within the School of Medicine and education courses taught within the School of Education, including courses in health sciences pedagogy, curriculum development, learning theory, quantitative, and qualitative research methods, statistics, and electives. To date, 16 students have entered the program, seven have passed their qualifying examinations, and five have earned their PhD degrees. Four students have received national recognition for their educational research and four graduates have obtained faculty appointments. Going forward, we must adapt the program's biomedical course requirements to incorporate the new integrated curriculum of the medical school, and we must secure additional funding to support more students. Overcoming these challenges will enable us to continue producing a small but stable supply of doctoral-level anatomy educators for a growing academic market. © 2014 American Association of Anatomists.

Methods for Analyzing the Attainment of Graduate School Milestones: A Case Study. GRE Board Professional Report No. 86-3P.

ERIC Educational Resources Information Center

Zwick, Rebecca; Braun, Henry I.

Using a data base compiled by the Graduate School of Northwestern University, a longitudinal study of the graduate school careers of 2,211 students in 14 programs was conducted. Among the most prominent findings was the increase in the enrollment of foreign students. The patterns of attainment of graduate school milestones, such as Ph. D.…

Student understanding of pH: "i don't know what the log actually is, i only know where the button is on my calculator".

PubMed

Watters, Dianne J; Watters, James J

2006-07-01

In foundation biochemistry and biological chemistry courses, a major problem area that has been identified is students' lack of understanding of pH, acids, bases, and buffers and their inability to apply their knowledge in solving acid/base problems. The aim of this study was to explore students' conceptions of pH and their ability to solve problems associated with the behavior of biological acids to understand the source of student difficulties. The responses given by most students are characteristic of an atomistic approach in which they pay no attention to the structure of the problem and concentrate only on juggling the elements together until they get a solution. Many students reported difficulty in understanding what the question was asking and were unable to interpret a simple graph showing the pH activity profile of an enzyme. The most startling finding was the lack of basic understanding of logarithms and the inability of all except one student to perform a simple calculation on logs without a calculator. This deficiency in high school mathematical skills severely hampered their understanding of pH. This study has highlighted a widespread deficiency in basic mathematical skills among first year undergraduates and a fragmented understanding of acids and bases. Implications for the way in which the concepts of pH and buffers are taught are discussed. Copyright © 2006 International Union of Biochemistry and Molecular Biology, Inc.

Eyeballs in the Fridge: Sources of early interest in science

NASA Astrophysics Data System (ADS)

Maltese, Adam V.; Tai, Robert H.

2010-03-01

This paper examines the experiences reported by scientists and graduate students regarding the experiences that first engaged them in science. The interviews analysed for this paper come from Project Crossover, a mixed-methods study of the transition from graduate student to PhD scientist in the fields of chemistry and physics. This analysis involved review of 116 interviews collected from graduate students and scientists and focused on the timing, source, and nature of their earliest interest in science. The majority (65%) of participants reported that their interest in science began before middle school. Females were more likely to report that their interest was sparked by school-related activities, while most males recounted self-initiated activities. Our findings indicate that current policy efforts (which focus on high school science reform) to increase the numbers of students studying in the science fields, may be misguided.

The First NEON School in La Silla

NASA Astrophysics Data System (ADS)

Dennefeld, M.; Melo, C.; Selman, F.

2016-06-01

The NEON Observing Schools have long provided PhD students with practical experience in the preparation, execution and reduction of astronomical observations, primarily at northern observatories. The NEON School was held in Chile for the first time, with observations being conducted at La Silla. The school was attended by 20 students, all from South America, and observations were performed with two telescopes, including the New Technology Telescope. A brief description of the school is presented and the observing projects and their results are described.

Assessment of oral health parameters among students attending special schools of Mangalore city.

PubMed

Peter, Tom; Cherian, Deepthi Anna; Peter, Tim

2017-01-01

The aim of the study was to assess the oral health status and treatment needs and correlation between dental caries susceptibility and salivary pH, buffering capacity and total antioxidant capacity among students attending special schools of Mangalore city. In this study 361 subjects in the age range of 12-18 years were divided into normal ( n = 84), physically challenged ( n = 68), and mentally challenged ( n = 209) groups. Their oral health status and treatment needs were recorded using the modified WHO oral health assessment proforma. Saliva was collected to estimate the salivary parameters. Statistical analysis was done using Statistical Package for Social Sciences version 17. Chicago. On examining, the dentition status of the study subjects, the mean number of decayed teeth was 1.57 for the normal, 2.54 for the physically challenged and 4.41 for the mentally challenged study subjects. These results were highly statistically significant ( P < 0.001). The treatment needs of the study subjects revealed that the mean number of teeth requiring pulp care and restoration were 1 for the normal, 0.12 for the physically challenged, and 1.21 for the mentally challenged study subjects. These results were highly statistically significant ( P < 0.001). The mean salivary pH and buffering capacity were found to be lowest among the mentally challenged subjects. Physically challenged group had the lowest mean total antioxidant capacity among the study subjects. Among the study subjects, normal students had the highest mean salivary pH, buffering capacity, and total antioxidant capacity. These results were highly statistically significant ( P < 0.001). This better dentition status of the normal compared to the physically and mentally challenged study subjects could be due to their improved quality of oral health practices. The difference in the treatment needs could be due to the higher prevalence of untreated dental caries and also due to the neglected oral health care among the mentally challenged study subjects. The salivary pH and buffering capacity were comparatively lower among the physically and mentally challenged study subjects which could contribute to their increased caries experience compared to the normal study subjects. However, further studies are needed to establish a more conclusive result on the total anti-oxidant capacity of the saliva and dental caries.

The Ph.D. Process - A Student's Guide to Graduate School in the Sciences

NASA Astrophysics Data System (ADS)

Bloom, Dale F.; Karp, Jonathan D.; Cohen, Nicholas

1999-02-01

The Ph.D. Process offers the essential guidance that students in the biological and physical sciences need to get the most out of their years in graduate school. Drawing upon the insights of numerous current and former graduate students, this book presents a rich portrayal of the intellectual and emotional challenges inherent in becoming a scientist, and offers the informed, practical advice a "best friend" would give about each stage of the graduate school experience. What are the best strategies for applying to a graduate program? How are classes conducted? How should I choose an advisor and a research project? What steps can I take now to make myself more "employable" when I get my degree? What goes on at the oral defense? Through a balanced, thorough examination of issues ranging from lab etiquette to stress management, the authors--each a Ph.D. in the sciences--provide the vital information that will allow students to make informed decisions all along the way to the degree. Headlined sections within each chapter make it fast and easy to look up any subject, while dozens of quotes describing personal experiences in graduate programs from people in diverse scientific fields contribute invaluable real-life expertise. Special attention is also given to the needs of international students.Read in advance, this book prepares students for each step of the graduate school experience that awaits them. Read during the course of a graduate education, it serves as a handy reference covering virtually all major issues and decisions a doctoral candidate is likely to face. The Ph.D. Process is the one book every graduate student in the biological and physical sciences can use to stay a step ahead, from application all the way through graduation.

Aflatoxin: An Old Carcinogen Teaches Us New Tricks | Division of Cancer Prevention

Cancer.gov

Speaker John D. Groopman, PhD Anna M. Baetjer Professor of Environmental Health Sciences Johns Hopkins Bloomberg School of Public Health Associate Director for Population Sciences Sidney Kimmel Comprehensive Cancer Center Johns Hopkins School of Medicine Baltimore, MD |

Summer Institute for High School Teachers

NASA Astrophysics Data System (ADS)

Maheswaranathan, Ponn; Calloway, Cliff

2008-04-01

We have conducted again a summer institute for high-school teachers in South Carolina at Winthrop University. The target audience were 9th grade physical science teachers in schools within a 50-mile radius from Winthrop. We developed a graduate level physics professional development course covering selected topics from the physics and chemistry content areas of the South Carolina Science Standards. Delivery of the material included the traditional lectures and the following innovative approaches in science teaching: hands-on experiments, group activities, computer based data collection, group discussions, and presentations. Two master teachers assisted us during the delivery of the course which took place in June 20-29, 2007 using Winthrop facilities. Requested funds were used for the following: salary for us and master teachers, contract course fee, some of the participants' room and board, startup equipment for all the teachers, and indirect costs to Winthrop University. Startup equipment included Pasco's stand-alone and portable Xplorer GLX interface and sensors (temperature, voltage, pH, pressure, motion, and sound). What we learned and ideas for continued K-12 teacher preparation initiatives will be presented.

Karl Krueger, PhD | Division of Cancer Prevention

Cancer.gov

Dr. Karl Krueger received a PhD in biochemistry from Vanderbilt University and continued his research training at NIH as a postdoctoral fellow before joining the faculty at Georgetown University School of Medicine. His research throughout this period focused on different aspects of drug receptors and their role in the nervous system. |

The PhD Project: How Successful Is It?

ERIC Educational Resources Information Center

Schwartz, Bill N.; Williams, Satina V.; Walden, W. Darrell

2011-01-01

The PhD Project's mission to diversify the work force by increasing the diversity of business school faculty is quite admirable, but is the Project successful? To gather insights toward responding to that question and to offer suggestions, we reviewed three of the Project's objectives that relate most closely to minority doctoral students and…

Titration of Serum Lipoproteins with Lipoprotein Precipitants.

DTIC Science & Technology

1981-12-01

Lipid Res 11:583 (1970). 6. Grove, T. H. Effect of reagent pH on determination of high-density lipo- protein cholesterol by precipitation with sodium ...of choles- terol in the supernate plateaued at 43 mg/dl after the beta and prebeta lipo- proteins had been precipitated . The intensities of the two...AD-A113 370 SCHOOL OF AEROSPACE MEDICINE BROOKS AFS TX F/S 6/1 TITRATION OF SERU’LIPOPROTEINS WITH LIPOPROTEIN PRECIPITANTS .(Ul DEC 81 0 A CLARK. J A

The thermal power of aluminum nitride at temperatures between 1350 and 1650 deg C in argon and nitrogen atmospheres. Ph.D. Thesis - Rhine-Westphalia High School at Aachen

NASA Technical Reports Server (NTRS)

Fischer, W. A.; Schuh, B.

1978-01-01

The test apparatus for measuring the thermal voltage of aluminum nitride for temperature differences of up to + or - 60 C between 1350 and 1650 C is described. The thermal power and its homogeneous proportion are determined and the heat transfer of the migration ions resulting from the homogeneous thermal power is calculated. The conduction mechanism in aluminum nitride is discussed.

Improving completion rates of students in biomedical PhD programs: an interventional study.

PubMed

Viđak, Marin; Tokalić, Ružica; Marušić, Matko; Puljak, Livia; Sapunar, Damir

2017-08-25

Analysis of graduation success at the University of Split School of Medicine PhD programs conducted in 2011 revealed that only 11% of students who enrolled and completed their graduate coursework between 1999 and 2011 earned a doctoral degree. In this prospective cohort study we evaluated and compared three PhD programs within the same medical school, where the newest program, called Translational Research in Biomedicine (TRIBE), established in the academic year 2010/11, aimed to increase the graduation rate through an innovative approach. The intervention in the new program was related to three domains: redefined recruitment strategy, strict study regulations, and changes to the curriculum. We compared performance of PhD students between the new and existing programs and analyzed their current status, time to obtain a degree (from enrolment to doctorate), age at doctorate, number of publications on which the thesis was based and the impact factor of journals in which these were published. These improvement strategies were associated with higher thesis completion rate and reduced time to degree for students enrolled in the TRIBE program. There was no change in the impact factor or number of publications that were the basis for the doctoral theses. Our study describes good practices which proved useful in the design or reform of the PhD training program.

IN MEMORIUM: Second International Workshop & Summer School on Plasma Physics 2006

NASA Astrophysics Data System (ADS)

2007-04-01

Zdravko Neichev, a PhD student at University of Sofia and a member of the Local Organising Committee of the International Workshop and Summer School on Plasma Physics, died September 22, 2006 at the age of 27 in a tragic car accident. He was close to finishing his PhD thesis working thoroughly in the field of Plasma Physics. Being also an excellent programmer he produced a number of perfect programs for numerical modelling of the coaxial discharge properties. He was a smart, friendly person, always ready to help. His colleagues and friends will never forget his radiant smile. Zdravko Neichev

Using social network analysis to examine collaborative relationships among PhD and DNP students and faculty in a research-intensive university school of nursing.

PubMed

Merrill, Jacqueline A; Yoon, Sunmoo; Larson, Elaine; Honig, Judy; Reame, Nancy

2013-01-01

The nursing profession has seen a dramatic rise in the number of schools offering both DNP and PhD nursing programs. Information is limited on the impact of this parallel approach in doctoral education on the quality and scope of scholarly interactions or institutional culture.The authors studied collaboration characteristics across the DNP and PhD programs of a research-intensive university school of nursing, before and after programmatic enhancements. An IRB-approved online survey was delivered to faculty and students of both programs at baseline and one year after curricular changes. Response rates were 70% and 74%, respectively. The responses were analyzed by using social network analysis and descriptive statistics to characterize the number and strength of connections between and within student groups, and between students and faculty. At baseline, the flow of communication was centralized primarily through faculty. At Time 2, density of links between students increased and network centralization decreased, suggesting more distributed communication. This nonlinear quantitative approach may be a useful addition to the evaluation strategies for doctoral education initiatives. Copyright © 2013 Elsevier Inc. All rights reserved.

The Bremen International Graduate School for Marine Sciences (GLOMAR) - Postgraduate education with an interdisciplinary focus

NASA Astrophysics Data System (ADS)

Klose, Christina

2013-04-01

The Bremen International Graduate School for Marine Sciences (GLOMAR) provides a dedicated research training programme for PhD students in all fields related the marine realm combined with an exceptional supervision and support programme in a stimulating research environment. The graduate school is part of MARUM - Center for Marine Environmental Sciences which is funded by the Deutsche Forschungsgemeinschaft (DFG) within the frame of the Excellence Initiative by the German federal and state governments to promote top-level research at German universities. GLOMAR hosts approx. 75 PhD students from different research institutions in Bremen and Bremerhaven. 50% of them are German, 50% have an international background. All students are a member of one of the four GLOMAR research areas: (A) Ocean & Climate, (B) Ocean & Seafloor, (C) Ocean & Life and (D) Ocean & Society. Their academic background ranges from the classical natural sciences to law, social and political sciences. The research areas are supervised by research associates who share their experience and offer advice for their younger colleagues. GLOMAR students work in an interdisciplinary and international context. They spend several months at a foreign research institution and are encouraged to actively participate in international conferences and publish their research results in international scientific journals. The services GLOMAR offers for its PhD students include team supervision by a thesis committee, a comprehensive course programme, research seminars and retreats, a family support programme, a mentoring programme for women in science, an ombudsperson and a funding system for conference trips, research residencies and publication costs. The graduate school offers different formats for interdisciplinary exchange within the PhD student community. Monthly research seminars, which are conducted by the GLOMAR research associates, provide an opportunity to discuss research results, practice oral and poster presentations and learn about methods in research fields other than their own. In the framework of two annual young scientist conferences, PhD students can learn how to organize a conference and practice their skills in presenting, discussing, chairing sessions and building their own network within the community of young scientists. Introductory and expert training courses cover a wide range of topics from different disciplines. More information about the graduate school and its programme can be found on the GLOMAR web page: http://www.marum.de/en/GLOMAR.html

What Took Them So Long? Explaining PhD Delays among Doctoral Candidates

PubMed Central

van de Schoot, Rens; Yerkes, Mara A.; Mouw, Jolien M.; Sonneveld, Hans

2013-01-01

A delay in PhD completion, while likely undesirable for PhD candidates, can also be detrimental to universities if and when PhD delay leads to attrition/termination. Termination of the PhD trajectory can lead to individual stress, a loss of valuable time and resources invested in the candidate and can also mean a loss of competitive advantage. Using data from two studies of doctoral candidates in the Netherlands, we take a closer look at PhD duration and delay in doctoral completion. Specifically, we address the question: Is it possible to predict which PhD candidates will experience delays in the completion of their doctorate degree? If so, it might be possible to take steps to shorten or even prevent delay, thereby helping to enhance university competitiveness. Moreover, we discuss practical do's and don'ts for universities and graduate schools to minimize delays. PMID:23935895

Medical education in Ecuador.

PubMed

Joffre, Carrillo P; Delgado, Belgica; Kosik, Russell Olive; Huang, Lei; Zhao, Xudong; Su, Tung-Ping; Wang, Shuu-Jiun; Chen, Qi; Fan, Angela Pei-Chen

2013-12-01

Ecuador, the smallest of the Andean countries, is located in the northwest portion of South America. The nation's 14.5 million people have a tremendous need for high quality primary care. To describe the profound advances as well as the persistent needs in medical education in Ecuador that have occurred with globalization and with the modernization of the country. Through an extensive search of the literature; medical school data; reports from the Ecuador Ministry of Public Health and Ministry of Education; and information from the National Secretary of Higher Education, Science, and Innovation (SENESCYT), the medical education system in Ecuador has been thoroughly examined. The National System of Higher Education in Ecuador has experienced significant growth over the last 20 years. As of 2009 the system boasts 19 medical schools, all of which offer the required education needed to obtain the title of Physician, but only 12 of which offer postgraduate clinical training. Of these 19 universities, nine are public, five are private and self-financed, and five are private and co-financed. Post-graduate options for medical students include: (1) Clinical specialization, (2) Higher diploma, (3) Course specialization, (4) Master's degree, and (5) PhD degree. The rapid growth of Ecuador's system of medical education has led to inevitable gaps that threaten its ability to sustain itself. Chief among these is the lack of well-trained faculty to supply its medical schools. To ensure an adequate supply of faculty exists, the creation of sufficient postgraduate, sub-specialization, and PhD training positions must be created and maintained.

Nicholas Brunhart-Lupo | NREL

Science.gov Websites

. Education Ph.D., Computer Science, Colorado School of Mines M.S., Computer Science, University of Queensland B.S., Computer Science, Colorado School of Mines Brunhart-Lupo Nicholas Brunhart-Lupo Computational Science Nicholas.Brunhart-Lupo@nrel.gov

Equality and Illusion: Gender and Tenure in Art History Careers

ERIC Educational Resources Information Center

Rudd, Elizabeth; Morrison, Emory; Sadrozinski, Renate; Nerad, Maresi; Cerny, Joseph

2008-01-01

Using a national survey of 508 art history Ph.D.s including data on graduate school performance and careers 10-15 years post-Ph.D., this study investigates gender, family, and academic tenure in art history, the humanities field with the highest proportion of women. Alternative hypotheses derived from three perspectives--termed here "clockwork,"…

Doctoral Education as Social Practice for Knowledge Development: Conditions and Demands Encountered by Industry PhD Students

ERIC Educational Resources Information Center

Wallgren, Lillemor; Dahlgren, Lars Owe

2005-01-01

This article reports on an empirical study of industry PhD students in the Swedish Graduate School for Applied IT and Software Engineering. The students were questioned in semi-structured interviews about their experiences of sharing their postgraduate studies between industrial and academic environments. The results from the first analysis…

A Model for Modern Nonlinear Noncontiguous Operations: The War in Burma, 1943 to 1945

DTIC Science & Technology

2003-05-01

Approved by: _________________________________________ Monograph Director Robert M. Epstein, Ph.D...Professor and Director Robert H. Berlin, Ph.D. Academic Affairs, School of Advanced Military Studies _________________________________________ Director...I would like to thank Dr Robert Epstein for his guidance during the production of this monograph. My thanks also go to my Wife, Aly, for her patience

The Two-Year College and the Ph.D. Surplus.

ERIC Educational Resources Information Center

Smith, Milton L.

1979-01-01

Describes a research study to determine if the recent increase and growth of two-year colleges will help to correct the imbalance of Ph.D.'s by increasing the number of available faculty and administrative positions. The results indicate that these schools will cause only a slight increase in the employment of doctoral-degree holders. (SF)

Time and the Paradigm of Operational Art - Authority and Responsibility of the Operational Artist in the Political Military Discourse

DTIC Science & Technology

2017-02-15

by LTC (GS) Thomas Kopsch German Army School of Advanced Military Studies United States Army Command and General Staff College Fort Leavenworth...NUMBER 9. SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) School of Advanced Military Studies 10. SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR...PhD __________________________________, Seminar Leader Eric Laforest, COL ___________________________________, Director, School of Advanced

Terrestrial soil pH and MAAT records based on the MBT/CBT in the southern South China Sea: implications for the atmospheric CO2 evolution in Southeast Asia

NASA Astrophysics Data System (ADS)

Dong, L.; Li, L.; Li, Q.; Zhang, C.

2013-12-01

Liang Dong1, Li Li1, Qianyu Li1,2, Chuanlun L. Zhang1,3 1State Key Laboratory of Marine Geology, Tongji University, Shanghai 200092, China 2School of Earth and Environment Sciences, University of Adelaide, SA 5005, Australia 3Department of Marine Sciences, University of Georgia, Athens, GA 30602, USA The methylation index of branched tetraethers (MBT) and/or the cyclization ratio of branched tetraethers (CBT) are derived from the branched glycerol dialkyl Glycerol tetraethers (GDGTs) of bacterial origin and are widely used to reconstruct the terrestrial soil pH and mean annual air temperature (MAAT); however, these proxies are less frequently used in the oceanic settings. Here we provide the first high resolution records of soil pH and MAAT since the last glacial maximum based on the sedimentary core of MD05-2896 in the southern South China Sea. The MAAT record exhibited typical glacial and interglacial cycles and was consistent with the winter insolation variation. The pH values were lower (6.4-7) in the glacial time and higher (7-8.4) in the interglacial time. Changes in soil pH allowed the evaluation of changes in soil CO2 based on the atmosphere-soil CO2 balance. The results imply that the lower winter MAAT variation with a lower winter atmospheric CO2 concentration might have resulted in a higher pH in the interglacial period. Our records provide a new insight into the evolution of atmospheric CO2 between glacial and interglacial cycles in East Asia. Key words: South China Sea, MBT/CBT, b-GDGTs, MAAT, pH

Sucessful Strategies for Empowering Students to Get High Paying and Rewarding Employment in Industry (and elsewhere)

NASA Astrophysics Data System (ADS)

Schwartz, Brian

2002-03-01

Physics students entering graduate school rarely think about (and more importantly take actions) concerning developing employment options and wider marketable skills while studying towards their Ph.D. degree. It is only as they are about to graduate that they begin thinking about the job market and start preparing a resume and take some initial steps in their job search. I call this the “series process” towards obtaining employment; that is, first go to graduate school, finish the Ph.D. program and then initiate a serious job search. A far better approach with a much higher success and satisfaction rate is the “parallel process” in which the graduate student takes proactive career steps throughout graduate studies. In this approach, the students treat their future career seriously and as a research and development project in parallel to (and as important as) thesis research. The proactive student sharpens such career management skills as resume and vita preparation, assesses and develops transferable skills, strengthens communication skills (especially oral), practices interviewing skills and most importantly continually and purposefully expands a network to colleagues and potential employers. Through a grant from National Science Foundation the author has operated a program at The Graduate Center to assists Ph.D. students in developing and enhancing their career management skills. We describe proven techniques that, if developed throughout the students’ graduate studies, greatly enhance their employment opportunities. We will focus on strategies that can (and should be used) to identify, qualify for and obtain employment in the industrial sector.

Assessment for Learning: Shifting Our Focus

ERIC Educational Resources Information Center

Rosemartin, Dennis S.

2013-01-01

The use of assessments in public schools in the United States to link student test scores to school performance has arguably transformed assessments into accountability tools. Dennis S. Rosemartin, a former elementary classroom teacher, is currently a PhD candidate at the University of Arizona. His area of specialization is teacher preparation and…

Diet and Cancer: The Fourth Paradigm

Cancer.gov

Walter C. Willett, MD, DrPH, an international expert in diet and nutrition, with posts as a Professor of Epidemiology and Nutrition and Chairman of the Department of Nutrition at Harvard School of Public Health and as Professor of Medicine at Harvard Medical School, presented "Diet and Cancer: The Fourth Paradigm".

Primary Events in vision - Investigation of Basic Eye Responses.

DTIC Science & Technology

1983-06-30

Lewis School of Applied & Engineering Physics CORNELL UNIVERSITY Ithaca, NY 30 JUNE 1983 SEF 2 PHASE REPORT Contract No. N62269.62-M-3270 APPROVED FOR...Ph.D. N62269-82-M-3270 9. PERFORMING ORGANIZATION NAME AND ADDRESS 10. PROGRAM ELEMENT. PROJECT. TASK School of Applied & Engineering Physics AREA

The Role of Veterans Affairs in Support of DOD in Biodefense

DTIC Science & Technology

2015-05-22

Director Anthony E. Carlson, PhD , Seminar Leader Yan Poirier, LCOL, Canadian Army , Director, School of Advanced Military Studies...like them, who wield great influencing, soft power. I am also thankful to Mr. Dixon, Ms. Joranko, and all the staff of the School of Advanced Military

Management PhD Candidates' Job Search: The Initial Interview.

ERIC Educational Resources Information Center

Hunt, Steven C.; Sawhney, Rajeev

2003-01-01

A survey of 200 doctoral students who interviewed with business schools at the Academy of Management conference received 74 responses. On average, they interviewed with 15.74 schools and did considerable preconference information gathering. Many complained of the physical conditions and lack of interviewer preparation. (Contains 20 references.)…

Who wants to enroll in health care PhD programs? An analysis of a nationwide graduate destination survey.

PubMed

Pan, Ying-Ju; Lee, Lung-Sheng

2012-06-01

PhD training is important for national human resource development in the era of the "knowledge economy". However, it is not clear what factors are associated with the decision of a master's degree graduate to pursue a PhD degree in health care, including medicine, public health, and nursing. It is postulated that the intention to pursue a PhD degree in health care is associated with a graduate's attributes, academic publication, socioeconomic status, and extent of financial support. A cross-sectional investigation was conducted to analyze data from the 2007 nationwide graduate destination survey in Taiwan. Logistic regression with a forward stepwise model selection strategy was applied to identify those significant factors related to the intention of master's degree graduates to pursue a PhD degree in health care. The predictive validity of the selected model was evaluated using the receiver operating characteristics curve analysis. Of the 1668 master's degree graduates who responded to the survey, only 240 (14.4%) indicated a desire to pursue a PhD degree. Seven factors are identified to be independently associated with the intention to pursue a PhD degree in health care, including female gender [odds ratio (OR)=0.18, 95% confidence interval: 0.13-0.26], more than 2 years in graduate school (OR=0.46), working during graduate school (OR=0.47), submission of conference and journal articles (OR=1.61 and 1.48, respectively), tuition source, and parents' educational level. The predictive validity of the selected model was 0.77. These findings provide an overview of potential PhD students in the field of health care. Based on this assessment, effective strategies need to be developed to attract and retain qualified candidates, as well as other types of PhD students who are in demand in this field. Copyright © 2012. Published by Elsevier B.V.

Pharmacoepidemiology at Nordic School of Public Health NHV: Examples from 1999 to 2014.

PubMed

Stålsby Lundborg, Cecilia; Gyllensten, Hanna; Hedna, Khedidja; Hakkarainen, Katja M; Lesén, Eva; Andersson Sundell, Karolina; Gyllensten, H; Hedna, K; Hakkarainen, K M; Lesén, E; Sundell, K Andersson

2015-08-01

Pharmacoepidemiology is a branch of public health and had a place at the Nordic School of Public Health. Courses, Master's theses and Doctorates of Public Health (DrPH) in Pharmacoepidemiology were a relatively minor, but still important part of the school's activities. This paper gives a short background, followed by some snapshots of the activities at NHV, and then some illustrative case-studies. These case-studies list their own responsible co-authors and have separate reference lists. In the Nordic context, NHV was a unique provider of training and research in pharmacoepidemiology, with single courses to complete DrPH training, as well as implementation of externally-funded research projects. With the closure of NHV at the end of 2014, it is unclear if such a comprehensive approach towards pharmacoepidemiology will be found elsewhere in the Nordic countries. © 2015 the Nordic Societies of Public Health.

The Management of Independent Secondary School Libraries in England and Wales: The Skills and Perceptions of Library Managers

ERIC Educational Resources Information Center

Turner, Richard; Matthews, Graham; Ashcroft, Linda; Farrow, Janet

2007-01-01

This paper investigates aspects of the management of independent secondary school libraries in England and Wales. It is based on a survey of 150 independent school library managers, with a response rate of 68.7 percent, which was carried out as part of an ongoing PhD research project. The paper considers a range of issues important to school…

Muddling Through: An Analysis of Security Force Assistance in Iraq

DTIC Science & Technology

2017-05-25

General David Petraeus who recommended that I write about this topic while at the US Army School of Advanced Military Studies. His request was in...Muddling Through: An Analysis of Security Force Assistance in Iraq A Monograph by MAJ William J. Denn III US Army School of Advanced Military...Leader James S. Powell, COL, PhD _________________________________, Director, School of Advanced Military Studies James C. Markert, COL

Is Graduate School Really for You? The Whos, Whats, Hows, and Whys of Pursuing a Master's or Ph.D.

ERIC Educational Resources Information Center

Seligman, Amanda I.

2012-01-01

Landing a job in today's academic job market is no easy feat. Is graduate school the answer? This informed and candid book provides anyone thinking about pursuing an advanced degree--and those who support them--with the inside scoop on what to expect in graduate school. Amanda I. Seligman helps potential students navigate graduate study--not just…

Can You Earn a Ph.D. in Economics in Five Years?

ERIC Educational Resources Information Center

Stock, Wendy A.; Finegan, T. Aldrich; Siegfried, John J.

2009-01-01

We investigate graduate school outcomes for students who entered economics Ph.D. programs in Fall 2002. Students in Top-15 ranked programs and those with higher verbal and quantitative GRE scores are less likely to have dropped out, but no more likely to have graduated. Those with undergraduate degrees from Top-60 U.S. liberal arts colleges and…

Achieving Adaptability through Inquiry Based Learning

DTIC Science & Technology

2010-06-01

BLACK, Ph.D. MICHELLE SAMS, Ph.D. Research Program Manager Director Training and Leader Development Division Technical review by Marisa...Learning 5a. CONTRACT OR GRANT NUMBER 5b. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) Thomas M. Duffy (Indiana University) and Pamela...ORGANIZATION NAME( S ) AND ADDRESS(ES) School of Education Army Management Staff College Indiana University 5500 21st Street 201

Prairie View A&M/Baylor College of Medicine SMART Summer Undergraduate Prostate Cancer Research Project

DTIC Science & Technology

2009-04-01

August, 2007 and is working as a technician while he prepares to take the MCAT and GRE exams and apply for MD/Ph.D. and DO/Ph.D. programs. 2007...degree and is working as a technician while he improves his MCAT score and applies to medical school. Mark was selected for significant PVAMU leadership

Robert Shoemaker, PhD | Division of Cancer Prevention

Cancer.gov

Dr. Robert Shoemaker obtained his PhD in human genetics from the Graduate School of Public Health of the University of Pittsburgh in 1975. Following postdoctoral experience at the Armed Forces Institute of Pathology he moved to the Children's Hospital Medical Center of Akron. His research on pediatric tumors led to an interest in the genetics of drug resistance and new drug

Cyber Flag: A Realistic Cyberspace Training Construct

DTIC Science & Technology

2008-03-27

sincere appreciation to my research committee, Dr Mark Kanko, Dr Bob Bills , and Dr Rick Raines, as well as my faculty advisor, Major Paul Williams ...Graduate School of Engineering and Management Air Force Institute of Technology Air University Air Education and Training Command In Partial... Williams , Ph.D. (Chairman) date ___________//SIGNED//________________ 22 Jan 08 Mark A. Kanko, Ph.D. (Member) date

Forensic odontology education:from undergraduate to PhD - a Brazilian experience.

PubMed

Dietrichkeit Pereira, J G; Frontanilla Recalde, T S; Barreto Costa, P; Jacometti, V; Vigorito Magalhães, L; Alves Da Silva, R H

2017-12-01

Forensic Odontology is a topic present in the majority of Dental Schools in Brazil, and due to this reality, some universities develop activities related to undergraduate and graduate students, from the Dentistry course until the Ph.D. degree. To present the education experience related to Forensic Odontology at School of Dentistry of Ribeirão Preto (USP - University of São Paulo), showing the strategies and activities in the different degrees (Dental course, Forensic Odontology Specialization Program, Specific Professional Training, Master, and Ph.D.). To the undergraduate students, many activities are developed in order to demonstrate all the possibilities that Forensic Dentistry allow, including theoretical and practical activities; in the Forensic Odontology Specialization Program, the dentists are trained to act as Forensic Odontologists in all its amplitude; in the Specific Professional Training, some courses are available, related to specific topics as DVI, Forensic Facial Reconstruction, Auditor in Dental Care Insurance and others; and in the Master and Ph.D. Programs, the professionals receive training in skills like teaching, research, student's guidance and others. In Brazil, Forensic Odontology is a well-known field in Dentistry and universities develop an important role in training a qualified workforce.

PER PhDs & bachelor's degrees

NASA Astrophysics Data System (ADS)

White, Susan C.

2017-02-01

Recently, the editor remarked to me that physics departments that offered a PhD with a specialization in Physics Education Research (PER) seemed to graduate more bachelor's degree recipients than those physics PhD departments that did not have the specialization. I was not convinced. That led to quite a bit of discussion between us. He compiled a list of PhD departments that advertised a PhD specialization in PER in the 2004, 2005, 2009, and 2010 editions of GradSchoolShopper, a publication of the American Institute of Physics. Since not every department responded reliably every year, I combined the 2004 and 2005 data and the 2009 and 2010 data. I then compared the departments that advertised a PER specialization during both timeframes (2004 and/or 2005 and 2009 and/or 2010) with physics PhD-granting departments that did not indicate the specialization at all.

[Publications in the Croatian medical journals by doctoral candidates at University of Zagreb School of Medicine].

PubMed

Sember, Marijan; Petrak, Jelka

2014-01-01

By searching Medline/PubMed bibliographic database we collected data on publications of two groups of PhD candidates who earned their PhD degrees at University of Zagreb Medical School in 2000 and 2010. We identifed their publications in the Croatian medical journals and separately in the Croatian language. First group of PhD candidates (y 2000) published in the Croatian journals 34% of all published papers, with a share of 29% in the Croatian language. Another group (y 2010) published in the Croatian journals 44% of all published papers in which the number of papers published in the Croatian journals in English language grow significantly (5% vs. 31%). The number of papers published in the Croatian language decreased to 13%. Our results agreed with the global decreasing trend of the number of medical papers in non-English languages. The importance of mother-tongue in the medical education and health care may have influence on preserving scientific communication in non-English medical journals.

Say the Word Islam: School Counselors and Muslim Children

ERIC Educational Resources Information Center

Saleem, Daa'iyah; Rasheed, Sakinah

2010-01-01

Two Muslim women who hold Ph.D.'s, a clinical and developmental psychologist and a teacher educator speak personally and professionally about important information school counselors need to know about Islam and providing services to Muslim children. First, the authors draw from personal experiences in parenting Muslim children who have come of age…

The Physically Handicapped and Health Impaired Children: Do They Prosper in Regular Toronto Elementary Schools?

ERIC Educational Resources Information Center

Larter, Sylvia E.

The experience of 88 physically handicapped and health impaired (PH/HI) children attending Toronto, Canada, regular elementary schools in either regular classes or "integrated" special education classes was assessed with regard to their academic, social, emotional, medical, and physical needs. The integrated classification meant they…

Molecular cell biology and advanced microscopy: an interview with Joshua Z. Rappoport.

PubMed

Rappoport, Joshua Z

2018-05-01

Dr Joshua Z Rappoport, PhD, speaks to Nawsheen Boodhun, Managing Editor. Rappoport completed his bachelor's degree in Biology at Brown University (RI, USA). He then went on to earn a PhD from the Program in Mechanisms of Disease and Therapeutics at the Mount Sinai School of Medicine Graduate School of Biological Sciences of New York University (USA). Rappoport spent the early parts of his career working as a postdoctoral researcher at the Laboratory of Cellular Biophysics based in The Rockefeller University (NY, USA). He was subsequently recruited as a tenured faculty member to work as part of the School of Biosciences at the University of Birmingham (UK). 2014 marked the return of Rappoport to the USA, where he is currently a Research Professor in Molecular Cell Biology at the Northwestern University Feinberg School of Medicine (IL, USA). He is also the Director of the Center for Advanced Microscopy (CAM) and Nikon Imaging Center (NIC), a large core facility consisting of eight members of staff that support around 200 different laboratories.

Government stewardship of the for-profit private health sector in Afghanistan.

PubMed

Cross, Harry E; Sayedi, Omarzaman; Irani, Laili; Archer, Lauren C; Sears, Kathleen; Sharma, Suneeta

2017-04-01

Since 2003, Afghanistan's largely unregulated for-profit private health sector has grown at a rapid pace. In 2008, the Ministry of Public Health (MoPH) launched a long-term stewardship initiative to oversee and regulate private providers and align the sector with national health goals. We examine the progress the MoPH has made towards more effective stewardship, consider the challenges and assess the early impacts on for-profit performance. We reviewed publicly available documents, publications and the grey literature to analyse the development, adoption and implementation of strategies, policies and regulations. We carried out a series of key informant/participant interviews, organizational capacity assessments and analyses of hospital standards checklists. Using a literature review of health systems strengthening, we proposed an Afghan-specific definition of six key stewardship functions to assess progress towards MoPH stewardship objectives. The MoPH and its partners have achieved positive results in strengthening its private sector stewardship functions especially in generating actionable intelligence and establishing strategic policy directions, administrative structures and a legal and regulatory framework. Progress has also been made on improving accountability and transparency, building partnerships and applying minimum required standards to private hospitals. Procedural and operational issues still need resolution and the MoPH is establishing mechanisms for resolving them. The MoPH stewardship initiative is notable for its achievements to date under challenging circumstances. Its success is due to the focus on developing a solid policy framework and building institutions and systems aimed at ensuring higher quality private services, and a rational long-term and sustainable role for the private sector. Although the MoPH stewardship initiative is still at an early stage, the evidence suggests that enhanced stewardship functions in the MoPH are leading to a more efficient and effective for-profit private sector. These successful early efforts offer high-leverage potential to rapidly scale up going forward. © VC The Author 2016. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine.

Stellar Works: Searching for the Lives of Women in Science

NASA Astrophysics Data System (ADS)

Woodman, Jennifer Elizabeth

While women have had a profound impact in the world of science, they struggle to gain an equal foothold in many science, technology, engineering, and mathematics (STEM) fields today. This has led to considerable public and private sector efforts to recruit women into these arenas. In order to understand how schools and nonprofits engage today's young women in STEM studies, this account includes time spent both in high school science classrooms and with ChickTech--a Portland-based organization that works to provide a pathway into tech careers for high school-aged girls. A historical perspective reveals that modern women aren't treading into completely uncharted territory, in spite of the current disparity of representation in today's STEM arenas. This perspective is offered via an examination of the lives of a group of extraordinary women who worked in astronomy at Harvard College Observatory from the late 1800s into the 1960s. While several noteworthy women are discussed, the focus here is on Cecilia Payne, the first person to earn a Ph.D. in astronomy at Harvard, and one of the 20th century's greatest astronomers. A great many people have never heard of her...yet.

Creating a pipeline of talent for informatics: STEM initiative for high school students in computer science, biology, and biomedical informatics

PubMed Central

Dutta-Moscato, Joyeeta; Gopalakrishnan, Vanathi; Lotze, Michael T.; Becich, Michael J.

2014-01-01

This editorial provides insights into how informatics can attract highly trained students by involving them in science, technology, engineering, and math (STEM) training at the high school level and continuing to provide mentorship and research opportunities through the formative years of their education. Our central premise is that the trajectory necessary to be expert in the emergent fields in front of them requires acceleration at an early time point. Both pathology (and biomedical) informatics are new disciplines which would benefit from involvement by students at an early stage of their education. In 2009, Michael T Lotze MD, Kirsten Livesey (then a medical student, now a medical resident at University of Pittsburgh Medical Center (UPMC)), Richard Hersheberger, PhD (Currently, Dean at Roswell Park), and Megan Seippel, MS (the administrator) launched the University of Pittsburgh Cancer Institute (UPCI) Summer Academy to bring high school students for an 8 week summer academy focused on Cancer Biology. Initially, pathology and biomedical informatics were involved only in the classroom component of the UPCI Summer Academy. In 2011, due to popular interest, an informatics track called Computer Science, Biology and Biomedical Informatics (CoSBBI) was launched. CoSBBI currently acts as a feeder program for the undergraduate degree program in bioinformatics at the University of Pittsburgh, which is a joint degree offered by the Departments of Biology and Computer Science. We believe training in bioinformatics is the best foundation for students interested in future careers in pathology informatics or biomedical informatics. We describe our approach to the recruitment, training and research mentoring of high school students to create a pipeline of exceptionally well-trained applicants for both the disciplines of pathology informatics and biomedical informatics. We emphasize here how mentoring of high school students in pathology informatics and biomedical informatics will be critical to assuring their success as leaders in the era of big data and personalized medicine. PMID:24860688

Creating a pipeline of talent for informatics: STEM initiative for high school students in computer science, biology, and biomedical informatics.

PubMed

Dutta-Moscato, Joyeeta; Gopalakrishnan, Vanathi; Lotze, Michael T; Becich, Michael J

2014-01-01

This editorial provides insights into how informatics can attract highly trained students by involving them in science, technology, engineering, and math (STEM) training at the high school level and continuing to provide mentorship and research opportunities through the formative years of their education. Our central premise is that the trajectory necessary to be expert in the emergent fields in front of them requires acceleration at an early time point. Both pathology (and biomedical) informatics are new disciplines which would benefit from involvement by students at an early stage of their education. In 2009, Michael T Lotze MD, Kirsten Livesey (then a medical student, now a medical resident at University of Pittsburgh Medical Center (UPMC)), Richard Hersheberger, PhD (Currently, Dean at Roswell Park), and Megan Seippel, MS (the administrator) launched the University of Pittsburgh Cancer Institute (UPCI) Summer Academy to bring high school students for an 8 week summer academy focused on Cancer Biology. Initially, pathology and biomedical informatics were involved only in the classroom component of the UPCI Summer Academy. In 2011, due to popular interest, an informatics track called Computer Science, Biology and Biomedical Informatics (CoSBBI) was launched. CoSBBI currently acts as a feeder program for the undergraduate degree program in bioinformatics at the University of Pittsburgh, which is a joint degree offered by the Departments of Biology and Computer Science. We believe training in bioinformatics is the best foundation for students interested in future careers in pathology informatics or biomedical informatics. We describe our approach to the recruitment, training and research mentoring of high school students to create a pipeline of exceptionally well-trained applicants for both the disciplines of pathology informatics and biomedical informatics. We emphasize here how mentoring of high school students in pathology informatics and biomedical informatics will be critical to assuring their success as leaders in the era of big data and personalized medicine.

Adventures in STEM: Lessons in Water Chemistry From Elementary School to Graduate School

NASA Astrophysics Data System (ADS)

Dittrich, T. M.

2014-12-01

I will present the accumulation of over 10 years of experience teaching STEM subjects to students ranging from 1st grade to graduate school. I was fortunate to gain a lot of valuable teaching experience while in graduate school in Boulder, CO and so many of my experiences center on opportunities for connecting with students in the field in CO. 3rd-5th grade field hikes - While helping at Jamestown Elementary School, I led hikes with a 3-5th grade class to an abandoned flourospar mine where the students were able to pick up beautiful purple fluorite crystals from the ground while discussing how mining works. During the hike back, we used field meters to measure the pH and conductivity of the stream and discussed the need to balance society's need for metals with the harmful effects of acid mine drainage. 9th, 10th grade STEM Academy at Skyline High School - During an NSF-sponsored fellowship, I had the opportunity to teach a STEM class to 9th and 10th graders where we used the engineering design process to a) design a tool to help a handicapped 3rd grader use the drinking fountain by herself and b) design a treatment system for cleaning up acid mine drainage. Undergraduate and Graduate Environmental Water Chemistry Field Trip - Students had the opportunity to tour two local mine sites to collect contaminated water that would be used in class for alkalinity titrations and pH, sulfate, and hardness measurements. They also collected water samples upstream and at multiple points downstream of a wastewater treatment plan and measured and graphed the dissolved oxygen "sag" in the river. My main teaching philosophy has two parts: 1) assume the students know nothing and 2) assume the students are even smarter than you think you are. This informs my approach to field trips by always starting from the beginning, but also not oversimplifying the topic. 1st graders on their best day can be very similar to graduate students on their worst.

"Know Your Well" A Groundwater Quality Project to Inform Students and Well-Owners

NASA Astrophysics Data System (ADS)

Olson, C.; Snow, D.; Samal, A.; Ray, C.; Kreifels, M.

2017-12-01

Over 15 million U.S. households rely on private, household wells for drinking water, and these sources are not protected under the Safe Drinking Water Act. Data on private well water quality is slowly being collected and evaluated from a number of different agencies, sources and projects. A new project is designed both for training high school students and to help assess the quality of water from rural domestic wells in Nebraska. This "crowd sourced" program engaging high school agricultural education programs, FFA chapters, and science classes with students sampling and testing water sampling from rural domestic wells from 12 districts across the state. Students and teachers from selected school were trained through multiple school visits, both in the classroom and in the field. Classroom visits were used to introduce topics such as water quality and groundwater, and testing methods for specific analytes. During the field visit, students were exposed to field techniques, the importance of accuracy in data collection, and what factors might influence the water in sampled wells. High school students learn to sample and test water independently. Leadership and initiative is developed through the program, and many experience the enlightenment that comes with citizen science. A customized mobile app was developed for ease of data entry and visualization, and data uploaded to a secure website where information was stored and compared to laboratory tests of the same measurements. General water quality parameters, including pH, electrical conductivity, major anions are tested in the field and laboratory, as well as environmental contaminants such as arsenic, uranium, pesticides, bacteria. Test kits provided to each class were used by the students to measure selected parameters, and then duplicate water samples were analyzed at a university laboratory. Five high schools are involved in the project during its first year. Nitrate, bacteria and pesticides represent major concerns for private well owners across the U.S. and preliminary results indicate that nitrate concentrations can range up to 70 mg/L, while detections of bacteria and traces of pesticide residues are consistent with other studies. This project will help both high school students and private well owner become better-informed about water quality in Nebraska.

Delaware GK-12: Improvement of Science Education in Vocational Technical High Schools Through Collaborative Learning and Coteaching

NASA Astrophysics Data System (ADS)

Madsen, J.; Skalak, K.; Watson, G.; Scantlebury, K.; Allen, D.; Quillen, A.

2006-12-01

With funding from the National Science Foundation, the University of Delaware (UD) in partnership with the New Castle County Vocational Technical School District (NCCoVoTech) in Delaware has initiated a GK-12 Program. In each of year this program, nine full time UD graduate students in the sciences, who have completed all or most of their coursework, will be selected to serve as fellows. Participation in the GK-12 program benefits the graduate fellows in many ways. In addition to gaining general insight into current issues of science education, the fellows enhance their experience as scientific researchers by directly improving their ability to effectively communicate complex quantitative and technical knowledge to an audience with multiple and diverse learning needs. In the first year of this project, fellows have been paired with high school science teachers from NCCoVoTech. These pairs, along with the principal investigators (PIs) of this program have formed a learning community that is taking this opportunity to examine and to reflect on current issues in science education while specifically addressing critical needs in teaching science in vocational technical high schools. By participating in summer workshops and follow-up meetings facilitated by the PIs, the fellows have been introduced to a number of innovative teaching strategies including problem-based learning (PBL). Fellow/teacher pairs have begun to develop and teach PBL activities that are in agreement with State of Delaware science standards and that support student learning through inquiry. Fellows also have the opportunity to engage in coteaching with their teacher partner. In this "teaching at the elbow of another", fellows will gain a better understanding of and appreciation for the complexities and nuances of teaching science in vocational technical high schools. While not taught as a stand-alone course in NCCoVoTech high schools, earth science topics are integrated into the science curriculum at nearly all levels from the freshman through the senior year. Three of the current group of nine fellows are engaged in Ph.D.-level research within the disciplines of astronomy and hydrology. They will bring this expertise into their collaboration with their practicing teachers with the goal of improving the understanding of earth science topics by high school students within a vocational technical school setting.

It's Tough out There for New Ph.D.'s, but Some Colleges Give Graduates a Leg up

ERIC Educational Resources Information Center

Roberts, Lee

2009-01-01

Todd Wolfson just finished graduate school at the University of Pennsylvania, and already he's landed a tenure-track teaching job in journalism and media studies at Rutgers University. One might think he's the embodiment of the academic dream, in which the struggle to earn a Ph.D. has long provided an entree to a fulfilling academic career. But…

Unmanned Tactical Autonomous Control and Collaboration Coactive Design

DTIC Science & Technology

2016-06-01

AUTONOMOUS CONTROL AND COLLABORATION COACTIVE DESIGN by Matthew S. Zach June 2016 Thesis Advisor: Dan Boger Second Reader: Scot Miller...POSTGRADUATE SCHOOL June 2016 Approved by: Dan Boger, Ph.D. Thesis Advisor Scot Miller Second Reader Dan Boger, Ph.D...assistance, and mentoring, I remain most grateful. I begin by thanking Dr. Dan Boger and Scot Miller for taking me on as a thesis student. You

Integrated School of Ocean Sciences: Doctoral Education in Marine Sciences in Kiel

NASA Astrophysics Data System (ADS)

Bergmann, Nina; Basse, Wiebke; Prigge, Enno; Schelten, Christiane; Antia, Avan

2016-04-01

Marine research is a dynamic thematic focus in Kiel, Germany, uniting natural scientists, economists, lawyers, philosophers, artists and computing and medical scientists in frontier research on the scientific, economic and legal aspects of the seas. The contributing institutions are Kiel University, GEOMAR Helmholtz Centre for Ocean Research Kiel, Kiel Institute for the World Economy and Muthesius University in Kiel. Marine science education in Kiel trains young scientists to investigate the role of the oceans in global change, risks arising from ocean usage and sustainable management of living and non-living marine resources. Basic fundamental research is supplemented with applied science in an international framework including partners from industry and public life. The Integrated School of Ocean Sciences (ISOS) established through the Cluster of Excellence "The Future Ocean", funded within the German Excellence Initiative, provides PhD candidates in marine sciences with interdisciplinary education outside of curricular courses. It supports the doctoral candidates through supplementary training, a framework of supervision, mentoring and mobility, the advisors through transparency and support of doctoral training in their research proposals and the contributing institutions by ensuring quality, innovation and excellence in marine doctoral education. All PhD candidates financed by the Helmholtz Research School for Ocean System Science and Technology (HOSST) and the Collaborative Research Centre 754 "Climate-biogeochemical interactions in the tropical ocean" (SFB 754) are enrolled at the ISOS and are integrated into the larger peer community. Over 150 PhD candidate members from 6 faculties form a large interdisciplinary network. At the ISOS, they sharpen their scientific profile, are challenged to think beyond their discipline and equip themselves for life after a PhD through early exposure to topics beyond research (e.g. social responsibility, public communication, global sustainability etc.). The primary advisor and at least one co-advisor form an advisory committee, committing to support the candidate in two mandatory meetings per year. Contrasting to other PhD programmes, ISOS emphasises on an open policy with voluntary participation for all other aspects of the programme, creating a unique environment that lives upon personal involvement and maximises tangible benefits for individual PhD candidates.

A High School-Collegiate Outreach Program in Chemistry and Biology Delivering Modern Technology in a Mobile Van

NASA Astrophysics Data System (ADS)

Craney, Chris; Mazzeo, April; Lord, Kaye

1996-07-01

During the past five years the nation's concern for science education has expanded from a discussion about the future supply of Ph.D. scientists and its impact on the nation's scientific competitiveness to the broader consideration of the science education available to all students. Efforts to improve science education have led many authors to suggest greater collaboration between high school science teachers and their college/university colleagues. This article reviews the experience and outcomes of the Teachers + Occidental = Partnership in Science (TOPS) van program operating in the Los Angeles Metropolitan area. The program emphasizes an extensive ongoing staff development, responsiveness to teachers' concerns, technical and on-site support, and sustained interaction between participants and program staff. Access to modern technology, including computer-driven instruments and commercial data analysis software, coupled with increased teacher content knowledge has led to empowerment of teachers and changes in student interest in science. Results of student and teacher questionnaires are reviewed.

Outreach and education in urban Los Angeles Schools: integration of research into middle and high school science curriculum through the NSF GK-12 SEE-LA program

NASA Astrophysics Data System (ADS)

Daniel, J. C.; Hogue, T. S.; Moldwin, M. B.; Nonacs, P.

2012-12-01

A National Science Foundation Graduate Teaching Fellows in K- 12 Education program at UCLA (SEE-LA; http://measure.igpp.ucla.edu/GK12-SEE-LA/ ) partners UCLA faculty and graduate students (fellows) with urban middle and high school science teachers and their students to foster programs of science and engineering exploration that bring the environment of Los Angeles into the classroom. UCLA science and engineering graduate fellows serve as scientists-in-residence at four partner schools to integrate inquiry-based science lessons, facilitate advancements in science content teaching, and ultimately, to improve their own science communication skills. As part of their fellowship, graduate students are required to develop three "major" lessons, including one based on their PhD research at UCLA. During the first four years of the project, the SEE-LA fellows have developed a range of research-based activities, including lessons on sustainable fisheries, ecosystems and remote sensing, earthquakes, urban water quality including invertebrate observations, and post-fire soil chemistry, among others. This presentation will provide an overview of the SEE-LA GK-12 program and development of research lessons that also address California State Science Standards. We also discuss potential sustainability of GK-12 type outreach and education programs. The SEE-LA program has provided development of graduate student communication and teaching skills while also contributing significantly to the integration of science education into K-12 curriculum in Los Angeles schools.

Differences between US Women’s and Men’s Careers in Astronomy: Results from the Longitudinal Study of Astronomy Graduate Students

NASA Astrophysics Data System (ADS)

Ivie, Rachel; White, Susan; Chu, Raymond Y.

2015-08-01

The Longitudinal Study of Astronomy Graduate Students (LSAGS), a joint project of the American Astronomical Society (AAS) and the American Institute of Physics (AIP), emerged from the Women in Astronomy II conference held in Pasadena, CA, USA in 2003. At the conference, concern about possible differential attrition for women arose from the relatively high percentage of female junior (student) AAS members compared to the lower representation of women among astronomy faculty members.The Committee for the Status of Women in Astronomy (CSWA) and the AAS Council concluded that a longitudinal study was needed to collect data about which variables affect career choices in astronomy and to determine whether any of these variables exert a disproportionate force on either sex. In 2007-08, the project team, under the direction of Rachel Ivie, Associate Director of AIP’s Statistical Research Center (SRC), asked all graduate students in astronomy and astrophysics in the US (~1500) to complete the first survey. The LSAGS follows this same group of students as they leave graduate school and enter their careers. In 2012-13, more than 800 responded to the second survey, and most had completed PhDs. We plan a third round of data collection in 2015.Results from the study show that there are statistically significant differences between women and men in dissertation research methods, PhD subfield, and ratings of graduate school advisors. We found that after graduate school, women were more likely than men to take a break from work of six months or longer and to have made accommodations for a partner’s career opportunities (the “two-body problem”). In turn, women were more likely to work outside the field of astronomy because they were more likely to have experienced the “two-body problem.” In addition, we found women were more likely than men to have experienced harassment or discrimination at school or work. Finally, even while controlling for employment sector and years since PhD, we found that on average, women have lower salaries than men. These findings have implications for programs seeking to increase the representation of women in astronomy and physics. Funded by National Science Foundation AST-1347723.

Laboratory outreach: student assessment of flow cytometer fluidics in zero gravity.

PubMed

Crucian, B; Norman, J; Brentz, J; Pietrzyk, R; Sams, C

2000-10-01

Due to the the clinical utility of the flow cytometer, the National Aeronautics and Space Administration (NASA) is interested in the design of a space flight-compatible cytometer for use on long-duration space missions. Because fluid behavior is altered dramatically during space flight, it was deemed necessary to validate the principles of hydrodynamic focusing and laminar flow (cytometer fluidics) in a true microgravity environment. An experiment to validate these properties was conducted by 12 students from Sweetwater High School (Sweetwater, TX) participating in the NASA Reduced Gravity Student Flight Opportunity, Class of 2000. This program allows high school students to gain scientific experience by conducting an experiment on the NASA KC-135 zero gravity laboratory aircraft. The KC-135 creates actual zero-gravity conditions in 30-second intervals by flying a highly inclined parabolic flight path. The experiment was designed by their mentor in the program, the Johnson Space Center's flow cytometrist Brian Crucian, PhD, MT(ASCP). The students performed the experiment, with the mentor, onboard the NASA zero-gravity research aircraft in April 2000.

Every Student Counts: Broadening Participation in the Geosciences through a Multiyear Internship Program

NASA Astrophysics Data System (ADS)

Sloan, V.

2010-12-01

The number of Ph.D.s from underrepresented populations graduating each year in the geosciences lags behind all other sciences including physics. This results in a dearth of minorities acting as role models in higher education. Overall, African Americans, Native Americans, and Hispanics comprised a total of 6% of the Ph.D. graduates in 2005 compared to about 27% of the general population. African Americans were the most poorly represented relative to their proportion in the U.S. population, comprising only 1% of Ph.D.s in the geosciences compared to 12% of the population. Only one African American woman Ph.D. graduated in the geosciences in the U.S. in each of 2004 and 2005, while proportionally one would expect 28 to obtain a Ph.D. each year. Our multiyear internship program, RESESS helps to carry students from underrepresented minority populations through to graduate programs by preparing them for graduate school. Our interns experience an authentic summer research experience at a university, the USGS, or UNAVCO, while doing an intensive writing course and working closely with a science and writing mentor. We continue mentoring during the academic year, as students apply for graduate school and scholarships, and present their research results at professional conferences. RESESS focuses on the Earth sciences and partners with SOARS, which focuses on atmospheric and related sciences. Our future goals include developing more RESESS pods elsewhere in the country, making it possible for students to do community-driven research, and increasing the diversity of support for the program through new and stronger partnerships with organizations such as the U.S.G.S., the National Parks Service, and other universities. In this paper, we will present current statistics on diversity in higher education in the geoscience, details of our program, and conclusions about effective means of supporting minority students in the bridge to graduate school. When the numbers are this low, every student counts. Diana Prado Garzon at work in summer of 2010.

Three Spokane Moms Save Their School Libraries

ERIC Educational Resources Information Center

Whelan, Debra Lau

2008-01-01

In this article, the author reports on how three women saved their school libraries and created an advocacy model for all. The dynamic trio: Lisa Layera Brunkan, the great researcher with exceptional people skills, Susan McBurney, the master organizer with a Ph.D. in linguistics, and Denette Hill, the numbers lady with fantastic business acumen,…

Is Man Free to Make Choices for Health?

ERIC Educational Resources Information Center

Douglass, Joseph H.

2010-01-01

This paper is reformatted and reprinted as part of the 40th Anniversary of the American Journal of Health Education. (originally School Health Review) Health Education--Our Heritage series. The original article appeared in the inaugural issue of School Health Review (Volume 1, September 1969, pp. 4-8). At the time, Joseph H. Douglass, Ph.D., was…

Integrated but Not Included: Exploring Quiet Disaffection in Mainstream Schools in China and India

ERIC Educational Resources Information Center

Yan, Feng; Jament, Johnson

2008-01-01

This paper quotes the qualitative data from one author's recent research (Feng, 2006, 2007) in China and the other author's ongoing PhD research in India. Both studies used multi-methods of data collection in mainstream school settings. This paper discusses the relatively under-researched topic of "quiet disaffection" of pupils with…

Degrees Conferred by Schools and Colleges of Pharmacy for the Academic Year 1980-81.

ERIC Educational Resources Information Center

Chasin, Steven H.

1982-01-01

Degrees conferred in 72 pharmacy schools (B.S., B.Pharm., Pharm.D., M.S., Ph.D., and honorary) are tabulated by college, state, and region and ethnic/minority group. Overall, the number of degrees declined five percent, following a downward trend begun in 1977-78, with variation by specific degree. (MSE)

Teacher Training for PhD Students and New Faculty in Economics

ERIC Educational Resources Information Center

Allgood, Sam; Hoyt, Gail; McGoldrick, KimMarie

2018-01-01

Past studies suggest that a majority of economics graduate students engage in teaching-related activities during graduate school and many go on to academic positions afterwards. However, not all graduate students are formally prepared to teach while in graduate school nor are they fully prepared to teach in their first academic position. The…

Advanced myopia, prevalence and incidence analysis.

PubMed

Greene, Peter R; Greene, Judith M

2018-04-01

Various high-percentage high-incidence medical conditions, acute or chronic, start at a particular age of onset t1 (years), accumulate or progress rapidly, with a system time constant t0 (years), typically from 1 week to 5 years, and then level off at a plateau level [Formula: see text], ultimately affecting 10-95% of the population. This report investigates the prevalence and incidence functions for myopia and high myopia as a function of age. Fundamental prevalence versus time and incidence versus time results allow continuous prediction of myopia and high myopia population fractions as a function of age. This is a retrospective study. Nine reports are calculated with N = 444,600 subjects. There were no interventions other than usual regular eye examinations and subsequent indicated refraction change. The main result is continuous prediction of myopia prevalence-time data along with incidence rate data (%/year), age of onset (years), system plateau level, and system time constant (years). These parameters apply to progressive myopia and high myopia (R < -6 D), useful over several decades. The primary finding of this research is that the prevalence ratio of high myopes (R < -6.0 D) to common myopes is expected to increase from 15% entering college to 45% or more after college and graduate school. These statistics are particularly relevant to the many years of study required by M.D., Ph.D., and M.D./Ph.D. programs.

Teaching biophysics. Strategies for recruiting and retaining minorities in physics and biophysics.

PubMed Central

Tanaka, J C; Gladney, L D

1993-01-01

Several strategies directed toward increasing the participation of minority students in physics and biophysics are presented. Since the number of minority students entering college with an interest in science and mathematics must be increased if we expect to see more students graduating in science, several programs aimed at increasing the level of instruction of physics and biology in urban middle schools and high schools are outlined. We also describe approaches designed to increase the retention of science major during the freshman core physics course where many potential science majors are lost. Increasing the number of minority students at the PhD level will rely increasingly on partnerships between research universities and historically black colleges and universities (HBCUs) and several programs already in effect are given as examples of such linkages. PMID:8369460

Transformation of TNT by Aquatic Plants,

DTIC Science & Technology

1996-01-01

ES) 8. PERFORMING ORGANIZATION REPORT NUMBER Department of Environmental Science and Engineering N/A George R. Brown School of Engineering Rice...Department of Environmental Science and Engineering at Rice University, Dr. Hughes teaches courses in Water and Wastewater Treatment, Biological Process...8:55 Chairperson’s Opening Remarks 1:40 Chairperson’s Remarks Alan J. M. Baker Ph.D., Reader in Environmental Science & Alan J. M. Baker, Ph.D

Decoupling of the minority PhD talent pool and assistant professor hiring in medical school basic science departments in the US.

PubMed

Gibbs, Kenneth D; Basson, Jacob; Xierali, Imam M; Broniatowski, David A

2016-11-17

Faculty diversity is a longstanding challenge in the US. However, we lack a quantitative and systemic understanding of how the career transitions into assistant professor positions of PhD scientists from underrepresented minority (URM) and well-represented (WR) racial/ethnic backgrounds compare. Between 1980 and 2013, the number of PhD graduates from URM backgrounds increased by a factor of 9.3, compared with a 2.6-fold increase in the number of PhD graduates from WR groups. However, the number of scientists from URM backgrounds hired as assistant professors in medical school basic science departments was not related to the number of potential candidates (R 2 =0.12, p>0.07), whereas there was a strong correlation between these two numbers for scientists from WR backgrounds (R 2 =0.48, p<0.0001). We built and validated a conceptual system dynamics model based on these data that explained 79% of the variance in the hiring of assistant professors and posited no hiring discrimination. Simulations show that, given current transition rates of scientists from URM backgrounds to faculty positions, faculty diversity would not increase significantly through the year 2080 even in the context of an exponential growth in the population of PhD graduates from URM backgrounds, or significant increases in the number of faculty positions. Instead, the simulations showed that diversity increased as more postdoctoral candidates from URM backgrounds transitioned onto the market and were hired.

Impact of nutrition and health education on rural pre-school children.

PubMed

Puri, R; Mehta, S

1994-01-01

Pre-school children (n = 155) belonging to low socio-economic group from eight creches in villages around Chandigarh, were imparted nutrition and health education (NHE) for one year. Appropriate teaching material in the form of songs, rhymes and roleplays were scientifically developed for the purpose. For impact evaluation, objective tools in the form of checklists were formulated and used. NHE on three aspects, i.e., personal hygiene (PH), food hygiene (FH) and recognition of foods (RF) was imparted by Balsevikas (BSs) incharge of the creches, daily in a non-formal manner, for one year and evaluated periodically. On PH only, children of the lowest income group improved significantly. On FH and RF, all children registered significant improvement as these two aspects, were under the direct control of BSs who enthused and involved the children by providing an interacting and stimulating environment. The results are encouraging and indicate the pre-school children are educable in NHE provided participatory and appropriate material and methods are used.

Bridges to the Doctorate: mentored transition to successful completion of doctoral study for underrepresented minorities in nursing science.

PubMed

Kim, Mi Ja; Holm, Karyn; Gerard, Peggy; McElmurry, Beverly; Foreman, Mark; Poslusny, Susan; Dallas, Constance

2009-01-01

Nursing has a shortage of doctorally-prepared underrepresented minority (URM) scientists/faculty. We describe a five-year University of Illinois at Chicago (UIC) Bridges program for URM master's students' transition to doctoral study and factors in retention/graduation from the PhD program. Four master' students from two partner schools were recruited/appointed per year and assigned UIC faculty advisors. They completed 10 UIC credits during master's study and were mentored by Bridges faculty. Administrative and financial support was provided during transition and doctoral study. Partner schools' faculty formed research dyads with UIC faculty. Seventeen Bridges students were appointed to the Bridges program: 12 were admitted to the UIC PhD program since 2004 and one graduated in 2007. Eight Bridges faculty research dyads published 5 articles and submitted 1 NIH R03 application. Mentored transition from master's through doctoral program completion and administrative/financial support for students were key factors in program success. Faculty research dyads enhanced the research climate in partner schools.

Effects of root medium pH on root water transport and apoplastic pH in red-osier dogwood (Cornus sericea) and paper birch (Betula papyrifera) seedlings.

PubMed

Zhang, W; Zwiazek, J J

2016-11-01

Soil pH is a major factor affecting plant growth. Plant responses to pH conditions widely vary between different species of plants. However, the exact mechanisms of high pH tolerance of plants are largely unknown. In the present study, we compared the pH responses of paper birch (Betula papyrifera) seedlings, a relatively sensitive species to high soil pH, with red-osier dogwood (Cornus sericea), reported to be relatively tolerant of high pH conditions. We examined the hypotheses that tolerance of plants to high root zone pH is linked to effective control of root apoplastic pH to facilitate nutrient and water transport processes In the study, we exposed paper birch and red-osier dogwood seedlings for six weeks to pH 5, 7 and 9 under controlled-environment conditions in hydroponic culture. Then, we measured biomass, gas exchange, root hydraulic conductivity, ferric chelate reductase (FCR) activity, xylem sap pH and the relative abundance of major elements in leaf protoplasts and apoplasts. The study sheds new light on the rarely studied high pH tolerance mechanisms in plants. We found that compared with paper birch, red-osier dogwood showed greater growth, higher gas exchange, and maintained higher root hydraulic conductivity as well as lower xylem sap pH under high pH conditions. The results suggest that the relatively high pH tolerance of dogwood is associated with greater water uptake ability and maintenance of low apoplastic pH. These traits may have a significant impact on the uptake of Fe and Mn by leaf cells. © 2016 German Botanical Society and The Royal Botanical Society of the Netherlands.

Field of Gifted Dreams: An Interview with Susan Assouline

ERIC Educational Resources Information Center

Henshon, Suzanna E.

2016-01-01

Susan G. Assouline is the director of the Belin-Blank Center, holds the Myron and Jacqueline N. Blank Endowed Chair in Gifted Education, and is a professor of school psychology. She received her BS in general science with a teaching endorsement, her EdS in school psychology, and her PhD in psychological and quantitative foundations, all from the…

Journalism Abstracts: M.A., M.S., Ph.D. Theses in Journalism and Mass Communication. Vol. 14.

ERIC Educational Resources Information Center

Popovich, Mark N., Ed.

This book is an annual compilation of master's theses and doctoral dissertations written in schools and departments of journalism and communication in the United States. The aim of the book is to improve the flow of information about current research to students and teachers in journalism schools, to scholars in related disciplines, and to…

Postgraduate Educational Research on Violence, Gender, and HIV/AIDS in and around Schools (1995-2004)

ERIC Educational Resources Information Center

Moletsane, R.; Madiya, N.

2011-01-01

Social issues such as HIV/AIDS, bullying, and violence have recently come to the fore in schooling and related research in South Africa. This article describes and critically analyses Masters and Ph.D. research done in education in the period 1995-2004, with particular reference to the voice given to social issues, namely: gender, violence, and…

"Communicating Quietly: Supporting Personal Growth with Meditation and Listening in Schools"

ERIC Educational Resources Information Center

Leoni, Julie

2006-01-01

This article argues that meditation and therapeutic listening have a place in school. The article starts by summarising the findings of PhD research into exclusion which gave rise to this argument and then goes on to explain exactly what is meant by the words: "meditation" and "therapeutic listening". In defining the words, details of how the…

Primary Headteachers: New Leadership Roles inside and outside the School

ERIC Educational Resources Information Center

Robinson, Susan

2011-01-01

This article considers some of the findings of research undertaken for a PhD into the changing educational agenda and its impact on the role of primary headteachers in England. During the course of the study from 2005-2009, as a result of government policy new roles for headteachers both inside and outside their school increasingly emerged. The…

Increasing the Department of the Navy’s Opportunities for Small Businesses and Non-Traditional Suppliers through Simplified Acquisitions Contracting and NAICS Targeting

DTIC Science & Technology

2013-08-01

Procurement Law & Policy Reviewed by: Released by: William R. Gates, Ph.D., Dean Jeffrey D. Paduan, Ph.D. Graduate School of Business...10 II. REVIEW AND ANALYSIS OF APPLICABLE LAW AND SCHOLARSHIP ..12 A. INTRODUCTION...Indefinite-Delivery task or delivery orders. Section 4004 of the Federal Acquisition Streamlining Act (FASA) of 1994, Public Law 103-355 (1994

Chancroid

MedlinePlus

... one half of infected men have only a single ulcer. Women often have 4 or more ulcers. ... MD, PhD, Assistant Professor in Medicine, Harvard Medical School; Assistant in Medicine, Division of Infectious Disease, Department ...

Hymenolepiasis

MedlinePlus

... also called hymenolepiasis. Causes Hymenolepis live in warm climates and are common in the southern United States. ... MD, PhD, Assistant Professor in Medicine, Harvard Medical School; Assistant in Medicine, Division of Infectious Disease, Department ...

Leprosy

MedlinePlus

... countries worldwide, and in temperate, tropical, and subtropical climates. About 100 cases per year are diagnosed in ... MD, PhD, Assistant Professor in Medicine, Harvard Medical School; Assistant in Medicine, Division of Infectious Disease, Department ...

Aspergillosis

MedlinePlus

... airway blockage Respiratory failure When to Contact a Medical Professional Call your provider if you develop symptoms ... Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School; Assistant in Medicine, Division of Infectious Disease, ...

Functional and rheological properties of proteins in frozen turkey breast meat with different ultimate pH.

PubMed

Chan, J T Y; Omana, D A; Betti, M

2011-05-01

Functional and rheological properties of proteins from frozen turkey breast meat with different ultimate pH at 24 h postmortem (pH(24)) have been studied. Sixteen breast fillets from Hybrid Tom turkeys were initially selected based on lightness (L*) values for each color group (pale, normal, and dark), with a total of 48 breast fillets. Further selection of 8 breast samples was made within each class of meat according to the pH(24). The average L* and pH values of the samples were within the following range: pale (L* >52; pH ≤5.7), normal (46 < L* < 52; 5.9 < pH <6.1), and dark (L* <46; pH ≥6.3), referred to as low, normal, and high pH meat, respectively. Ultimate pH did not cause major changes in the emulsifying and foaming properties of the extracted sarcoplasmic and myofibrillar proteins. An SDS-PAGE profile of proteins from low and normal pH meat was similar, which revealed that the extent of protein denaturation was the same. Low pH meat had the lowest water-holding capacity compared with normal and high pH meat as shown by the increase in cooking loss, which can be explained by factors other than protein denaturation. Gel strength analysis and folding test revealed that gel-forming ability was better for high pH meat compared with low and normal pH meat.Dynamic viscoelastic behavior showed that myosin denaturation temperature was independent of pH(24). Normal and high pH meat had similar hardness, springiness, and chewiness values as revealed by texture profile analysis. The results from this study indicate that high pH meat had similar or better functional properties than normal pH meat. Therefore, high pH meat is suitable for further processed products, whereas low pH meat may need additional treatment or ingredient formulations to improve its functionality.

Core Competencies for Doctoral Education in Public Health

PubMed Central

Calhoun, Judith G.; Weist, Elizabeth M.; Raczynski, James M.

2012-01-01

The Association of Schools of Public Health (ASPH) released the Doctor of Public Health (DrPH) Core Competency Model in 2009. Between 2007 and 2009, a national expert panel with members of the academic and practice communities guided by the ASPH Education Committee developed its 7 performance domains, including 54 competencies. We provide an overview and analysis of the challenges and issues associated with the variability in DrPH degree offerings, reflect on the model development process and related outcomes, and discuss the significance of the model, future applications, and challenges for integration across educational settings. With the model, ASPH aims to stimulate national discussion on the competencies needed by DrPH graduates with the new challenges of 21st-century public health practice and to better define the DrPH degree. PMID:22095342

The Changing Pattern of Doctoral Education in Public Health From 1985 to 2006 and the Challenge of Doctoral Training for Practice and Leadership

PubMed Central

Declercq, Eugene; Caldwell, Karen; Hobbs, Suzanne Havala; Guyer, Bernard

2008-01-01

We examined trends in doctoral education in public health and the challenges facing practice-oriented doctor of public health (DrPH) programs. We found a rapid rise in the numbers of doctoral programs and students. Most of the increase was in PhD students who in 2006 composed 73% of the total 5247 current public health doctoral students, compared with 53% in 1985. There has also been a substantial increase (40%) in students in DrPH programs since 2002. Challenges raised by the increased demand for DrPH practice-oriented education relate to admissions, curriculum, assessment processes, and faculty hiring and promotion. We describe approaches to practice-based doctoral education taken by three schools of public health. PMID:18633094

Researcher Interview: Elaine Mardis

Cancer.gov

Elaine Mardis Ph.D., Professor of Medicine at Washington University School of Medicine, discusses her translational research applying genomics techniques to clinical trials, and forecasts the future of team science and cancer genomics.

Creeping eruption

MedlinePlus

... eruption is more common in countries with warm climates. In the United States, the Southeast has the ... MD, PhD, Assistant Professor in Medicine, Harvard Medical School; Assistant in Medicine, Division of Infectious Disease, Department ...

Whipworm infection

MedlinePlus

... the world, especially in countries with warm, humid climates. Some outbreaks have been traced to contaminated vegetables ( ... MD, PhD, Assistant Professor in Medicine, Harvard Medical School; Assistant in Medicine, Division of Infectious Disease, Department ...

Experimental Evolution of Escherichia coli K-12 at High pH and RpoS Induction.

PubMed

Hamdallah, Issam; Torok, Nadia; Bischof, Katarina M; Majdalani, Nadim; Chadalavada, Sriya; Mdluli, Nonto; Creamer, Kaitlin E; Clark, Michelle; Holdener, Chase; Basting, Preston J; Gottesman, Susan; Slonczewski, Joan L

2018-05-25

Experimental evolution of Escherichia coli K-12 W3110 by serial dilutions for 2,200 generations at high pH extended the range of sustained growth from pH 9.0 to pH 9.3. pH 9.3-adapted isolates showed mutations in DNA-binding regulators and envelope proteins. One population showed an IS1 knockout of phoB (positive regulator of the phosphate regulon). A phoB :: kanR knockout increased growth at high pH. phoB mutants are known to increase production of fermentation acids, which could enhance fitness at high pH. Mutations in pcnB (poly(A) polymerase) also increased growth at high pH. Three out of four populations showed deletions of torI, an inhibitor of TorR, which activates expression of torCAD (trimethylamine N-oxide respiration) at high pH. All populations showed point mutations affecting the stationary-phase sigma RpoS, either in the coding gene or in regulators of RpoS expression. RpoS is required for survival in extreme base. In our microplate assay, rpoS deletion slightly decreased growth at pH 9.1. RpoS protein accumulated faster at pH 9 than at pH 7. The RpoS accumulation at high pH required the presence of one or more antiadapters that block degradation (IraM, IraD, and IraP). Other genes with mutations after high pH evolution encode regulators such as yobG ( mgrB ) (PhoPQ regulator), rpoN (nitrogen starvation sigma), malI , and purR ; as well as envelope proteins ompT and yahO Overall, E. coli evolution at high pH selects for mutations in key transcriptional regulators, including phoB and the stationary-phase sigma RpoS. IMPORTANCE Escherichia coli in its native habitat encounters high pH stress such as that of pancreatic secretions. Experimental evolution over 2,000 generations showed selection for mutations in regulatory factors, such as deletion of the phosphate regulator PhoB and mutations that alter function of the global stress regulator RpoS. RpoS is induced at high pH via multiple mechanisms. Copyright © 2018 American Society for Microbiology.

Stress and burnout in postgraduate dental education.

PubMed

Divaris, K; Polychronopoulou, A; Taoufik, K; Katsaros, C; Eliades, T

2012-02-01

High levels of stress and burnout have been documented among dental students and practicing dentists, but evidence among dental residents and postgraduate students is lacking. Ninety-nine postgraduate students enrolled in clinical, non-clinical and PhD programmes in the Athens University School of Dentistry completed the Graduate Dental Environment Stress (GDES) questionnaire and the Maslach Burnout Inventory. Perceived stress was measured in two domains, academic (GDES-A) and clinical (GDES-C) and burnout was measured using the scales of emotional exhaustion (EE), depersonalisation (DP) and personal accomplishment (PA). Analyses relied on descriptive, univariate and multivariate methods based on ANOVA and generalised linear models. Participants' mean age was 30 years; two-thirds were women and practised dentistry independently of their graduate studies. Residents in clinical programmes reported significantly higher levels of perceived stress compared to non-clinical and PhD students (P<0.05). There were no gender differences in perceived stress. Forty per cent of respondents were burnout 'cases' on the EE scale, while this proportion was 38% for reduced PA and smaller, 13% for DP. Perceived stress was positively correlated with all burnout dimensions, whereas independent dental practice and higher age had a protective effect. High rates of burnout manifestations were detected among this sample of Greek postgraduate dental students. Perceived stress correlated with burnout and was more pronounced among those enrolled in clinical residency compared to non-clinical and PhD programmes. © 2011 John Wiley & Sons A/S.

Arsenic and iron removal from groundwater by oxidation-coagulation at optimized pH: laboratory and field studies.

PubMed

Bordoloi, Shreemoyee; Nath, Suresh K; Gogoi, Sweety; Dutta, Robin K

2013-09-15

A three-step treatment process involving (i) mild alkaline pH-conditioning by NaHCO₃; (ii) oxidation of arsenite and ferrous ions by KMnO₄, itself precipitating as insoluble MnO₂ under the pH condition; and (iii) coagulation by FeCl₃ has been used for simultaneous removal of arsenic and iron ions from water. The treated water is filtered after a residence time of 1-2 h. Laboratory batch experiments were performed to optimize the doses. A field trial was performed with an optimized recipe at 30 households and 5 schools at some highly arsenic affected villages in Assam, India. Simultaneous removals of arsenic from initial 0.1-0.5 mg/L to about 5 μg/L and iron from initial 0.3-5.0 mg/L to less than 0.1 mg/L have been achieved along with final pH between 7.0 and 7.5 after residence time of 1h. The process also removes other heavy elements, if present, without leaving any additional toxic residue. The small quantity of solid sludge containing mainly ferrihydrite with adsorbed arsenate passes the toxicity characteristic leaching procedure (TCLP) test. The estimated recurring cost is approximately USD 0.16 per/m(3) of purified water. A high efficiency, an extremely low cost, safety, non-requirement of power and simplicity of operation make the technique potential for rural application. Copyright © 2013 Elsevier B.V. All rights reserved.

Predictors of Student Productivity in Biomedical Graduate School Applications.

PubMed

Hall, Joshua D; O'Connell, Anna B; Cook, Jeanette G

2017-01-01

Many US biomedical PhD programs receive more applications for admissions than they can accept each year, necessitating a selective admissions process. Typical selection criteria include standardized test scores, undergraduate grade point average, letters of recommendation, a resume and/or personal statement highlighting relevant research or professional experience, and feedback from interviews with training faculty. Admissions decisions are often founded on assumptions that these application components correlate with research success in graduate school, but these assumptions have not been rigorously tested. We sought to determine if any application components were predictive of student productivity measured by first-author student publications and time to degree completion. We collected productivity metrics for graduate students who entered the umbrella first-year biomedical PhD program at the University of North Carolina at Chapel Hill from 2008-2010 and analyzed components of their admissions applications. We found no correlations of test scores, grades, amount of previous research experience, or faculty interview ratings with high or low productivity among those applicants who were admitted and chose to matriculate at UNC. In contrast, ratings from recommendation letter writers were significantly stronger for students who published multiple first-author papers in graduate school than for those who published no first-author papers during the same timeframe. We conclude that the most commonly used standardized test (the general GRE) is a particularly ineffective predictive tool, but that qualitative assessments by previous mentors are more likely to identify students who will succeed in biomedical graduate research. Based on these results, we conclude that admissions committees should avoid over-reliance on any single component of the application and de-emphasize metrics that are minimally predictive of student productivity. We recommend continual tracking of desired training outcomes combined with retrospective analysis of admissions practices to guide both application requirements and holistic application review.

Unionville, Pennsylvania School's Stream Restoration Project

NASA Astrophysics Data System (ADS)

Madsen, S. M.

2004-12-01

For the past three years, students and Earth Club members of C.F. Patton Middle School and Unionville High School have been involved in a stream restoration and monitoring project along a tributary to the East Branch of the Red Clay Creek in Pennsylvania. The Red Clay is within the larger Christina River Basin watershed which drains to Delaware Bay. Total funding of \\$962.00 was awarded by the Unionville-Chadds Ford Education Foundation to purchase both stream monitoring equipment and native plant species for stream restoration. Nine science teachers in the school district received certification in stream monitoring by the Pennsylvania State Parks Division. Certification enables the science faculty and their students to enter monitoring data in a statewide stream database. The stream data includes: temperature, levels of dissolved oxygen and nutrients, pH, alkalinity, conductivity, and a complete biosurvey of invertebrates. In addition to ongoing monitoring, the Earth Club sponsored a name-the-stream contest. Quartz Creek was chosen for this previously unnamed tributary. Its' name was approved by the East Marlborough Township Supervisor in May, 2004 and was then submitted to the USGS' Board on Geographic Names. The Earth Club has also sponsored a stream restoration contest. Students in the middle school were encouraged to design a habitat along the stream banks that would keep sediment in-place, while encouraging wildlife. The stream was originally crowded with invasive multi-flora rose but this was removed with the help of parents and students over a two year period. The winning student poster was outstanding and native species were purchased and planted following the poster's design. The planting took place in May, 2004 with over 40 persons involved including 25 middle school and 8 high school students, teachers from the schools, administrators and employees of the Brandywine Conservancy, and Red Clay Valley and Brandywine Valley Associations, and graduate students from the University of Delaware.

Processed dairy beverages pH evaluation: consequences of temperature variation.

PubMed

Ferreira, Fabiana Vargas; Pozzobon, Roselaine Terezinha

2009-01-01

This study assessed the pH from processed dairy beverages as well as eventual consequences deriving from different ingestion temperatures. 50 adults who accompanied children attended to at the Dentistry School were randomly selected and they answered a questionnaire on beverages. The beverages were divided into 4 groups: yogurt (GI) fermented milk (GII), chocolate-based products (GIII) and fermented dairy beverages (GIV). They were asked which type, flavor and temperature. The most popular beverages were selected, and these made up the sample. A pH meter Quimis 400A device was used to verify pH. The average pH from each beverage was calculated and submitted to statistical analysis (Variance and Tukey test with a 5% significance level). for groups I, II and III beverages, type x temperature interaction was significant, showing the pH averages were influenced by temperature variation. At iced temperatures, they presented lower pH values, which were considered statistically significant when compared to the values found for the same beverages at room temperature. All dairy beverages, with the exception of the chocolate-based type presented pH below critical level for enamel and present corrosive potential; as to ingestion temperature, iced temperature influenced pH reducing its values, in vitro.

Imperforate hymen

MedlinePlus

... 149. Sucato GS, Murray PJ. Pediatric and adolescent gynecology. In: Zitelli, BJ, McIntire SC, Norwalk AJ, eds. ... by: Irina Burd, MD, PhD, Associate Professor of Gynecology and Obstetrics at Johns Hopkins University School of ...

Preterm labor

MedlinePlus

... SG, Niebyl JR, Simpson JL, et al, eds. Obstetrics: Normal and Problem Pregnancies . 7th ed. Philadelphia, PA: ... Burd, MD, PhD, Associate Professor of Gynecology and Obstetrics at Johns Hopkins University School of Medicine, Baltimore, ...

Decoupling of the minority PhD talent pool and assistant professor hiring in medical school basic science departments in the US

PubMed Central

Gibbs, Kenneth D; Basson, Jacob; Xierali, Imam M; Broniatowski, David A

2016-01-01

Faculty diversity is a longstanding challenge in the US. However, we lack a quantitative and systemic understanding of how the career transitions into assistant professor positions of PhD scientists from underrepresented minority (URM) and well-represented (WR) racial/ethnic backgrounds compare. Between 1980 and 2013, the number of PhD graduates from URM backgrounds increased by a factor of 9.3, compared with a 2.6-fold increase in the number of PhD graduates from WR groups. However, the number of scientists from URM backgrounds hired as assistant professors in medical school basic science departments was not related to the number of potential candidates (R2=0.12, p>0.07), whereas there was a strong correlation between these two numbers for scientists from WR backgrounds (R2=0.48, p<0.0001). We built and validated a conceptual system dynamics model based on these data that explained 79% of the variance in the hiring of assistant professors and posited no hiring discrimination. Simulations show that, given current transition rates of scientists from URM backgrounds to faculty positions, faculty diversity would not increase significantly through the year 2080 even in the context of an exponential growth in the population of PhD graduates from URM backgrounds, or significant increases in the number of faculty positions. Instead, the simulations showed that diversity increased as more postdoctoral candidates from URM backgrounds transitioned onto the market and were hired. DOI: http://dx.doi.org/10.7554/eLife.21393.001 PMID:27852433

Graduate Pharmacoeconomic and Outcomes Research Educational Programs in Colleges and Schools of Pharmacy: A Five-Year Update.

ERIC Educational Resources Information Center

Jackson, Terrence R.; Draugalis, JoLaine R.

2000-01-01

A survey of all 41 U.S. schools and colleges of pharmacy offering social/administrative sciences graduate programs found a substantial increase in the number of programs and participants, and expected completions. Fellows were most apt to secure an industry post upon program completion; PhD graduates were most apt to accept a position with the…

Examining the Practice of Information Literacy Teaching and Learning in Vietnamese Upper Secondary Schools

ERIC Educational Resources Information Center

Ngo, Huyen; Walton, Geoff

2016-01-01

Information literacy (IL) research has been hitherto dominated by the USA, Australia and the UK [22]. Vietnam, however, remains under-represented and there is no IL work in upper secondary schools in the country to date. This paper, which is part of an ongoing PhD research, presents preliminary findings of the study to understand IL level of…

Learning from Successful School-based Vaccination Clinics during 2009 pH1N1

ERIC Educational Resources Information Center

Klaiman, Tamar; O'Connell, Katherine; Stoto, Michael A.

2014-01-01

Background: The 2009 H1N1 vaccination campaign was the largest in US history. State health departments received vaccines from the federal government and sent them to local health departments (LHDs) who were responsible for getting vaccines to the public. Many LHD's used school-based clinics to ensure children were the first to receive limited…

Aspirations and Tensions in Developing International Mindedness: Case Study of Two Students in an IB School in an Indian Ocean Island Nation

ERIC Educational Resources Information Center

Poonoosamy, Mico

2016-01-01

International mindedness is considered by many educational researchers and organizations as a determining feature in international education. This article used data as part of a PhD case study inquiry to explore how international mindedness is developed by two students in an IB school in an Indian Ocean Island Nation. Through a qualitative…

Understanding Roles of Social Media in Academic Engagement and Satisfaction for Graduate Students

DOE Office of Scientific and Technical Information (OSTI.GOV)

Han, Kyungsik; Volkova, Svitlana; Corley, Courtney D.

Research indicates positive effects of social media in academia and education. However its main populations have been faculty, teachers, high school or college students, and its primary contexts have been course or classroom settings. We realized there exists a lack of studies on how Ph.D. (broadly graduate) students use social media for academic purposes and how its use is associated with academic motivation, engagement, and satisfaction, which are salient factors for the success of their graduate degrees and life. Based on the survey responses from 91 current Ph.D. students, our study results highlight that (1) students mainly use social mediamore » for broadcasting and keeping up with up-to-date academic and research information; yet, making connections and developing professional networks is one of the primary reasons, and (2) social media use is positively associated with their academic engagement and satisfaction. We discuss implications and future work of our study.« less

Determination of Prevalence of Dental Erosion in 12 - 14 Years School Children and Its Relationship with Dietary Habits.

PubMed

Shahbaz, Uzma; Quadir, Fauzia; Hosein, Tasleem

2016-07-01

To determine the frequency of dental erosion in 12-14 years school children and its association with dietary habits. Observational cross-sectional analytical study. Fatima Jinnah Dental College, Karachi, from January to June 2010. School children aged between 12 - 14 years were included in this study. Dental erosion was detected by visual examination. Aself-developed questionnaire was used to assess the dietary habits of children. Acidic diet was considered a diet that has an acidic pH. The amount of consumption of acidic drinks and food per week was categorized into low consumption (1 - 7 times / week) and medium consumption (8 - 21 times / week). Chi-square test was applied to see any statistical difference between diet and tooth erosion at 95% CI. The results showed a high frequency of (46%) dental erosion in children, which was significantly higher (p < 0.001) in children with more acidic diet. This study highlights the impact of dietary habits on the prevalence of dental erosion in children. Acidic diets need to be controlled in frequency to prevent dental erosion.

David Farrar Mitchell: dental researcher & educator.

PubMed

Christen, Arden G; Christen, Joan A

2008-01-01

David Farrar Mitchell, DDS, PhD (1918-1975), was a pioneer in aviation dentistry and a leader in dental education, service and research. In the mid-1940's, he was the first dental officer assigned to the School of Aviation Medicine (SAM) in San Antonio, Texas, a unique, Army Air Corps organization for research and teaching. From 1942-1946, as a trained dental researcher and oral pathologist, he published works on dental problems afflicting military aviators, especially those associated with high altitude flying. His work greatly influenced ongoing dental treatment of military flyers. He served as faculty chairman of two dental schools: The University of Minnesota (1948-1955) and Indiana University (1955-1975). Of his 33 graduate students in oral pathology/medicine, 28 became department chairs at dental schools throughout the world. He was president of the American Academy of Oral Pathology (1962) and of the American Association for Dental Research (1975). From 1969 to 1975, he was editor of the prestigious Journal of Dental Research. During his professional career, Dr. Mitchell published 120 scientific articles on diverse topics relating to oral diagnosis and oral medicine.

A profile of U.S. nursing faculty in research- and practice-focused doctoral education.

PubMed

Smeltzer, Suzanne C; Sharts-Hopko, Nancy C; Cantrell, Mary Ann; Heverly, Mary Ann; Nthenge, Serah; Jenkinson, Amanda

2015-03-01

This study, which is part of a larger project, was conducted to profile the nursing faculty in the United States teaching in PhD and DNP programs. This is a descriptive study. A sample of 554 nursing faculty who teach in PhD and DNP programs was recruited by email solicitation to represent all geographic regions of the United States. Data were collected from November 2013 through January 2014 using an online survey instrument. The instrument was developed based on results of review of the literature and of focus groups of doctoral faculty (faculty teaching in doctoral programs) to ascertain characteristics of faculty teaching in doctoral programs and of the schools in which they teach. Frequencies and descriptive statistics are reported. Growth in DNP programs has outpaced growth in PhD programs, and DNP graduates have moved into doctoral education in greater numbers than PhD graduates. DNP faculty report less prior experience and current productivity scholarship than faculty in PhD programs only or both types of programs. Strategies are needed to ensure that doctoral programs are staffed by faculty who are prepared for doctoral education and the development of nursing science. The Institute of Medicine has recommended doubling the number of doctorally prepared nurses in the United States by 2020 to ensure that sufficient numbers of faculty are available to prepare the nursing labor force that is needed for delivery of healthcare services. Nurse scientists are needed to contribute to improvement in patient care quality and safety, and practice leaders are needed to facilitate the translation of research into safe, high-quality, and cost-effective care. The landscape of doctoral education in nursing is rapidly changing. © 2015 Sigma Theta Tau International.

Sanitary Survey of the Schools of Orange County, Virginia. Report of an Investigation by the Virginia State Board of Health, the Department of Education of the University of Virginia, and the Virginia State Department of Education. Bulletin, 1914, No. 17. Whole Number 590

ERIC Educational Resources Information Center

Flannagan, Roy K.

1914-01-01

In January, 1913, Ennion U. William, M. D., commissioner of health of Virginia; Hon. Joseph D. Eggleston, retiring superintendent of public instruction; R. C. Stearns, his successor; and W. H. Heck, Ph. D., professor of education in the University of Virginia, projected an intensive survey of the white and colored schools and school children of…

77 FR 39999 - Marine Mammals; File No. 17278

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-06

... James Shine, Ph.D., Harvard University School of Public Health, 401 Park Drive, 404H West, Boston... scientific research. DATES: Written, telefaxed, or email comments must be received on or before August 6...

Hemangioma

MedlinePlus

... 38. Review Date 10/24/2016 Updated by: David L. Swanson, MD, Vice Chair of Medical Dermatology, Associate Professor of Dermatology, Mayo Medical School, Scottsdale, AZ. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the ...

Spider angioma

MedlinePlus

... 650. Review Date 10/24/2016 Updated by: David L. Swanson, MD, Vice Chair of Medical Dermatology, Associate Professor of Dermatology, Mayo Medical School, Scottsdale, AZ. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the ...

Rhinophyma

MedlinePlus

... 7. Review Date 10/24/2016 Updated by: David L. Swanson, MD, Vice Chair of Medical Dermatology, Associate Professor of Dermatology, Mayo Medical School, Scottsdale, AZ. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the ...

Planck focal plane instruments: advanced modelization and combined analysis

NASA Astrophysics Data System (ADS)

Zonca, Andrea; Mennella, Aniello

2012-08-01

This thesis is the result of my work as research fellow at IASF-MI, Milan section of the Istituto di Astrofisica Spaziale e Fisica Cosmica, part of INAF, Istituto Nazionale di Astrofisica. This work started in January 2006 in the context of the PhD school program in Astrophysics held at the Physics Department of Universita' degli Studi di Milano under the supervision of Aniello Mennella. The main topic of my work is the software modelling of the Low Frequency Instrument (LFI) radiometers. The LFI is one of the two instruments on-board the European Space Agency Planck Mission for high precision measurements of the anisotropies of the Cosmic Microwave Background (CMB). I was also selected to participate at the International Doctorate in Antiparticles Physics, IDAPP. IDAPP is funded by the Italian Ministry of University and Research (MIUR) and coordinated by Giovanni Fiorentini (Universita' di Ferrara) with the objective of supporting the growing collaboration between the Astrophysics and Particles Physics communities. It is an international program in collaboration with the Paris PhD school, involving Paris VI, VII and XI Universities, leading to a double French-Italian doctoral degree title. My work was performed with the co-tutoring of Jean-Michel Lamarre, Instrument Scientist of the High Frequency Instrument (HFI), the bolometric instrument on-board Planck. Thanks to this collaboration I had the opportunity to work with the HFI team for four months at the Paris Observatory, so that the focus of my activity was broadened and included the study of cross-correlation between HFI and LFI data. Planck is the first CMB mission to have on-board the same satellite very different detection technologies, which is a key element for controlling systematic effects and improve measurements quality.

Biology, literacy, and the African American voice: A case study of meaningful learning in the biology classroom

NASA Astrophysics Data System (ADS)

Reese, Keturah

Under the direction of Sharon Murphy Augustine, Ph.D./Ph.D Curriculum and Instruction There was a substantial performance gap among African Americans and other ethnic groups. Additionally, African American students in a Title I school were at a significantly high risk of not meeting or exceeding on performance tests in science. Past reports have shown average gains in some subject areas, and declines in others (NCES, 2011; GADOE, 2012). Current instructional strategies and the lack of literacy within the biology classroom created a problem for African American high school students on national and state assessments. The purpose of this study was to examine the perceptions of African American students and teachers in the context of literacy and biology through the incorporation of an interactive notebook and other literacy strategies. The data was collected three ways: field notes for a two week observation period within the biology classroom, student and teacher interviews, and student work samples. During the observations, student work collection, and interviews, I looked for the following codes: active learning, constructive learning, collaborative learning, authentic learning, and intentional learning. In the process of coding for the pre-determined codes, three more codes emerged. The three codes that emerged were organization, studying/student ownership, and student teacher relationships. Students and teachers both solidified the notion that literacy and biology worked well together. The implemented literacy strategies were something that both teachers and students appreciated in their learning of biology. Overall students and teachers perceived that the interactive notebook along Cornell notes, Thinking maps, close reads, writing, lab experiments, and group work created meaningful learning experiences within the biology classroom.

BSA-coated nanoparticles for improved SERS-based intracellular pH sensing.

PubMed

Zheng, Xiao-Shan; Hu, Pei; Cui, Yan; Zong, Cheng; Feng, Jia-Min; Wang, Xin; Ren, Bin

2014-12-16

Local microenvironment pH sensing is one of the key parameters for the understanding of many biological processes. As a noninvasive and high sensitive technique, surface-enhanced Raman spectroscopy (SERS) has attracted considerable interest in the detection of the local pH of live cells. We herein develop a facile way to prepare Au-(4-MPy)-BSA (AMB) pH nanosensor. The 4-MPy (4-mercaptopyridine) was used as the pH sensing molecule. The modification of the nanoparticles with BSA not only provides a high sensitive response to pH changes ranging from pH 4.0 to 9.0 but also exhibits a high sensitivity and good biocompatibility, stability, and reliability in various solutions (including the solutions of high ionic strength or with complex composition such as the cell culture medium), both in the aggregation state or after long-term storage. The AMB pH nanosensor shows great advantages for reliable intracellular pH analysis and has been successfully used to monitor the pH distribution of live cells and can address the grand challenges in SERS-based pH sensing for practical biological applications.

Partnership for development: A peer mentorship model for PhD students.

PubMed

Lewinski, Allison A; Mann, Tara; Flores, Dalmacio; Vance, Ashlee; Bettger, Janet Prvu; Hirschey, Rachel

Formal mentoring relationships socialize Doctor of Philosophy (PhD) students to their current and future roles as nursing scholars. Despite formal mentoring, some students may desire or benefit from additional mentoring in an informal setting. Informal mentoring complements the one-to-one relationship students develop with a primary faculty mentor or dissertation chair. This manuscript describes the development, implementation, and evaluation of a student-driven, peer mentorship model, titled Partnership for Development. This small group, peer mentorship model was implemented in a PhD program at a School of Nursing during an academic year. Five student peer facilitators organized a total of 32 PhD students, 2 post-doctoral associates, and invited 5 faculty to participate. Data includes pre- and post-implementation surveys completed by the students and peer facilitator field notes. Student reported post-participation benefits included: getting to know faculty in an informal setting (n=6), socializing with students from other cohorts (n=6), and obtaining a sense of camaraderie with other PhD students (n=5). We recommend peer mentorship for other PhD programs as a way to socialize PhD students into the role of nurse scientist and assist students during their tenure as a PhD student. Copyright © 2017 Elsevier Inc. All rights reserved.

The Roles of the Bone Marrow Microenvironment in Controlling Tumor Dormancy

DTIC Science & Technology

2015-10-01

Shiozawa, M.D., Ph.D. CONTRACTING ORGANIZATION: Wake Forest School of Medicine Ann Arbor, MI 48109 REPORT DATE: October 2015 TYPE OF REPORT...PERFORMING ORGANIZATION REPORT NUMBER Wake Forest University Health Sciences Medical Center Blvd. Winston-Salem NC 27157 9. SPONSORING... Wake Forest School of Medicine as of 03/01/15. The PI obtained the necessary institutional approvals (IACUC, IRB, IBC) and submitted the grant

Dental Caries Status, Socio-Economic, Behavioral and Biological Variables among 12-Year-Old Palestinian School Children.

PubMed

Sgan-Cohen, H D; Bajali, M; Eskander, L; Steinberg, D; Zini, A

2015-01-01

There are currently inadequate data regarding the prevalence of dental caries and its associated variables, among Palestinian children. To determine the current prevalence of dental caries and related variables, among Palestinian children in East Jerusalem. A stratified sample of 286 East Jerusalem Palestinian children was selected, employing randomly chosen sixth grade clusters from three pre-selected socio-economic school groups. Dental caries was recorded according to WHO recommendations. Salivary flow, pH, buffer capacity and microbial parameters, were recorded according to previously employed methodologies. The mean level of caries experience, by DMFT, was 1.98 ± 2.05. This level was higher than those found among Israeli children, but lower than several other Middle Eastern countries. In uni-variate analysis, significant associations were revealed between caries and school categories, which indicated lower, middle and higher socio-economic position(SEP), mothers' employment, home densities, dental visits, tooth brushing, Streptococci mutans (SM), Lactobacilli (LB), and saliva pH. According to a linear logistic regression model, children learning in lower SEP schools, with higher SM levels and more acidic saliva, had a higher chance of experiencing dental caries. These findings should be considered in the planning of services and dental health care programs for Palestinian children.

Non-Linear Metamodeling Extensions to the Robust Parameter Design of Computer Simulations

DTIC Science & Technology

2016-09-15

design By principal component analysis," Total Quality Management, vol. 8, no. 6, pp. 409-416, 1997. [25] A. Salmasnia, R. B . Kazemzadeh and S. T . A...and D. T . Sturrock, Simulation with Arena (3rd ed.), New York, NY: McGraw-Hill, 2004. [85] A. M. Mathai and S. B . Provost, Quadratic Forms in Random...PhD Member ADEDEJI B . BADIRU, PhD Dean, Graduate School of Engineering and Management iv AFIT-ENS-DS-16-S-026 Abstract Robust

Pathogenesis of Dengue Vaccine Viruses in Mosquitoes.

DTIC Science & Technology

1982-07-01

r AD Af29 019 PA I4OGENESIS OF DENGUE VACCINE VIRUSES IN MOSQITOES U) YALE UNIV NEW YIAVEN CONN SCHOOL OF MEDICINE B JBEAT ET AL 01 JUL 82 DAMD1779...1963-A ’UNCLASS IFIET) .AD.- PATHOGENESIS OF DENGUE VACCINE VIRUSES IN MOSQUITOES FINAL REPORT Barry J. Beaty, Ph.D. Thomas H. G. Aitken, Ph.D. July 1...NUMBER 4. TITLE (mid Subdl.) S. KVPE OF REPORT & PERIOD COVERED PATHOGENESIS OF DENGUE VACCINE VIRUSES Final Scientific Report IN MOSQUITOES 6/1/79 to 6

Impaired drug absorption due to high stomach pH: a review of strategies for mitigation of such effect to enable pharmaceutical product development.

PubMed

Mitra, Amitava; Kesisoglou, Filippos

2013-11-04

Published reports have clearly shown that weakly basic drugs which have low solubility at high pH could have impaired absorption in patients with high gastric pH thus leading to reduced and variable bioavailability. Since such reduction in exposure can lead to significant loss of efficacy, it is imperative to (1) understand the behavior of the compound as a function of stomach pH to inform of any risk of bioavailability loss in clinical studies and (2) develop a robust formulation which can provide adequate exposure in achlorhydric patients. In this review paper, we provide an overview of the factors that can cause high gastric pH in human, discuss clinical and preclinical pharmacokinetic data for weak bases under conditions of normal and high gastric pH, and give examples of formulation strategies to minimize or mitigate the reduced absorption of weakly basic drugs under high gastric pH conditions. It should be noted that the ability to overcome pH sensitivity issues is highly compound dependent and there are no obvious and general solutions to overcome such effect. Further, we discuss, along with several examples, the use of biopharmaceutical tools such as in vitro dissolution, absorption modeling, and gastric pH modified animal models to assess absorption risk of weak bases in high gastric pH and also the use of these tools to enable development of formulations to mitigate such effects.

Cancer Prevention: Opportunities for Action

Cancer.gov

Leslie Bernstein, PhD, AFLAC, Inc., Chair in Cancer Research; Professor, Preventive Medicine; and Senior Associate Dean, Faculty Affairs at Keck School of Medicine, University of Southern California, Los Angeles, CA, presented "Cancer Prevention: Opportunities for Action".

Environmental Measurement in Schools: Electronics in Field Studies.

ERIC Educational Resources Information Center

Crellin, J. R.

1978-01-01

The use of environmental meters designed to measure conductivity, light level, oxygen, pH, sound, and temperature are discussed. Criteria for choosing suitable equipment are suggested and, where possible, cheaper alternatives are mentioned. (Author/BB)

Tracheitis

MedlinePlus

... Otolaryngology – Head and Neck Surgery, The University of Texas Medical School at Houston, Houston, TX. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team. team. Staphylococcal Infections Read more Tracheal ...

Fungal nail infection

MedlinePlus

... 268. Review Date 10/24/2016 Updated by: David L. Swanson, MD, Vice Chair of Medical Dermatology, Associate Professor of Dermatology, Mayo Medical School, Scottsdale, AZ. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the ...

Electrochemical behavior and pH stability of artificial salivas for corrosion tests.

PubMed

Queiroz, Gláucia Maria Oliveira de; Silva, Leandro Freitas; Ferreira, José Tarcísio Lima; Gomes, José Antônio da Cunha P; Sathler, Lúcio

2007-01-01

It is assumed that the compositions of artificial salivas are similar to that of human saliva. However, the use of solutions with different compositions in in vitro corrosion studies can lead dissimilar electrolytes to exhibit dissimilar corrosivity and electrochemical stability. This study evaluated four artificial salivas as regards pH stability with time, redox potentials and the polarization response of an inert platinum electrode. The tested solutions were: SAGF medium, Mondelli artificial saliva, UFRJ artificial saliva (prepared at the School of Pharmacy, Federal University of Rio de Janeiro, RJ, Brazil) and USP-RP artificial saliva (prepared at the School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, SP, Brazil). It was observed that pH variations were less than 1 unit during a 50-hour test. The SAGF medium, and the UFRJ and USP-RP solutions exhibited more oxidizing characteristics, whereas the Mondelli solution presented reducing properties. Anodic polarization revealed oxidation of the evaluated electrolytes at potentials below +600 mV SCE. It was observed that the UFRJ and USP-RP solutions presented more intense oxidation and reduction processes as compared to the Mondelli and SAGF solutions.

Are race, ethnicity, and medical school affiliation associated with NIH R01 type 1 award probability for physician investigators?

PubMed

Ginther, Donna K; Haak, Laurel L; Schaffer, Walter T; Kington, Raynard

2012-11-01

To analyze the relationship among National Institutes of Health (NIH) R01 Type 1 applicant degree, institution type, and race/ethnicity, and application award probability. The authors used 2000-2006 data from the NIH IMPAC II grants database and other sources to determine which individual and institutional characteristics of applicants may affect the probability of applications being awarded funding. They used descriptive statistics and probit models to estimate correlations between race/ethnicity, degree (MD or PhD), and institution type (medical school or other institution), and application award probability, controlling for a large set of observable characteristics. Applications from medical schools were significantly more likely than those from other institutions to receive funding, as were applications from MDs versus PhDs. Overall, applications from blacks and Asians were less likely than those from whites to be awarded funding; however, among applications from MDs at medical schools, there was no difference in funding probability between whites and Asians, and the difference between blacks and whites decreased to 7.8%. The inclusion of human subjects significantly decreased the likelihood of receiving funding. Compared with applications from whites, applications from blacks have a lower probability of being awarded R01 Type 1 funding, regardless of the investigator's degree. However, funding probability is increased for applications with MD investigators and for those from medical schools. To some degree, these advantages combine so that applications from black MDs at medical schools have the smallest difference in funding probability compared with those from whites.

Are Race, Ethnicity, and Medical School Affiliation Associated With NIH R01 Type Award Probability for Physician Investigators?

PubMed Central

Ginther, Donna K.; Haak, Laurel L.; Schaffer, Walter T.; Kington, Raynard

2012-01-01

Purpose To analyze the relationship among NIH R01 Type 1 applicant degree, institution type, and race/ethnicity, and application award probability. Method The authors used 2000–2006 data from the NIH IMPAC II grants database and other sources to determine which individual and institutional characteristics of applicants may affect the probability of applications being awarded funding. They used descriptive statistics and probit models to estimate correlations between race/ethnicity, degree (MD or PhD), and institution type (medical school or other institution), and application award probability, controlling for a large set of observable characteristics. Results Applications from medical schools were significantly more likely than those from other institutions to receive funding, as were applications from MDs versus PhDs. Overall, applications from blacks and Asians were less likely than those from whites to be awarded funding; however, among applications from MDs at medical schools, there was no difference in funding probability between whites and Asians and the difference between blacks and whites decreased to 7.8 percentage points. The inclusion of human subjects significantly decreased the likelihood of receiving funding. Conclusions Compared with applications from whites, applications from blacks have a lower probability of being awarded R01 Type 1 funding, regardless of the investigator’s degree. However, funding probability is increased for applications with MD investigators and for those from medical schools. To some degree, these advantages combine so that applications from black MDs at medical schools have the smallest difference in funding probability compared with those from whites. PMID:23018334

Evidence of an association between sign language phonological awareness and word reading in deaf and hard-of-hearing children.

PubMed

Holmer, Emil; Heimann, Mikael; Rudner, Mary

2016-01-01

Children with good phonological awareness (PA) are often good word readers. Here, we asked whether Swedish deaf and hard-of-hearing (DHH) children who are more aware of the phonology of Swedish Sign Language, a language with no orthography, are better at reading words in Swedish. We developed the Cross-modal Phonological Awareness Test (C-PhAT) that can be used to assess PA in both Swedish Sign Language (C-PhAT-SSL) and Swedish (C-PhAT-Swed), and investigated how C-PhAT performance was related to word reading as well as linguistic and cognitive skills. We validated C-PhAT-Swed and administered C-PhAT-Swed and C-PhAT-SSL to DHH children who attended Swedish deaf schools with a bilingual curriculum and were at an early stage of reading. C-PhAT-SSL correlated significantly with word reading for DHH children. They performed poorly on C-PhAT-Swed and their scores did not correlate significantly either with C-PhAT-SSL or word reading, although they did correlate significantly with cognitive measures. These results provide preliminary evidence that DHH children with good sign language PA are better at reading words and show that measures of spoken language PA in DHH children may be confounded by individual differences in cognitive skills. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

The Production of Black Ph.D.’s in Economics at Harvard University, 1905–19551

PubMed Central

Myers, Samuel L.

2018-01-01

Harvard University’s Economics Department produced some of the leading African American economists between World War I and the Korean War. This essay explores the factors that contributed to this accomplishment and documents the career trajectories of the six blacks who obtained the Doctorate in Economics from Harvard University during the period 1905–1955. The analysis reveals the pivotal roles of the Rosenwald Fund, Classical High Schools, Black Fraternal Organizations and former University of Minnesota Applied Economics Professor, John D. Black. A common outcome of the careers of these six pioneers was a commitment to black economic empowerment. PMID:29937590

ESSReS-PEP-POLMAR, an international and interdisciplinary postgraduate education concept on Earth and Environmental Sciences

NASA Astrophysics Data System (ADS)

Meggers, Helge; Hanfland, Claudia; Sprengel, Claudia; Grosfeld, Klaus; Lohmann, Gerrit; Bijma, Jelle; Ladstätter-Weißenmayer, Annette; Burrows, John

2014-05-01

Postgraduate education is gaining increasing importance and has been identified as one instrument to foster quality and promote networking, both in research and in education. Exchange and co-operation between graduate programmes that have related topics produce added value for all. Students have access to a range of research facilities, course offers, and a broad scientific community from which they can start building their individual scientific network. Larger events like PhD conferences, career symposia or cost-intensive trainings are more easily tackled by joining forces of various players. The postgraduate programmes ESSReS-PEP-POLMAR are part of a larger network of marine and climate science programmes in the north-western region of Germany and together host up 180 (23 ESSReS, 130 POLMAR, 30 PEP) PhD/Master students in their respective programmes. Here, we will present a number of joint activities from this collaboration. Today, the PhD education is completely different to that from 15 years ago due to a variety of different scientific offerings including e.g. excursions, soft skill courses and special seminars. In the framework of the ESSReS-PEP-POLMAR concept the Postgraduate Programme Environmental Physics (PEP) at the University of Bremen educates the participants on the complex relationship between atmosphere, hydrosphere (ocean), cryosphere (ice region) and solid earth (land). Here, the learning of experimental methods in environmental physics at the most advanced level, numerical data analysis using supercomputers, and data interpretation via sophisticated methods prepare students for a scientific career. Within cooperation with the Ocean University of China (OUC) students are participating one year in the PEP programme during their master studies since 2006, to get finally a double degree of both universities. Two different ways to further graduation are currently possible at the Alfred Wegener Institute. The Helmholtz Graduate School for Polar and Marine Research (POLMAR) provides a coherent framework for a structured postgraduate programme. POLMAR is a trans disciplinary umbrella organization for currently 130 PhD students and combines high-level science qualification in the various disciplines of polar and marine research with other key qualifications through joint seminars, lectures and practical training. Doctoral education within POLMAR is structured systematically and adapted to the individual needs of the PhD students. The Earth System Science Research School (ESSReS) covers 23 PhD students working at the Alfred Wegener Institute, Helmholtz Center for Polar and Marine Research, the Jacobs University and the University of Bremen. The ESSReS aims at the integration of research at the interface of Biology, Physics, Geophysics, Mathematics and Informatics. It is therefore multi- and interdisciplinary in every aspect. The training, curriculum, and PhD research subjects are closely located at the interfaces between the participating disciplines. This is guaranteed by interdisciplinary supervision of the PhD project, documented by the members of the "PhD committee". The long-term goal is not only to enhance exchange and interaction between these disciplines, but to enforce a new integrated concept, where separation between disciplines becomes obsolete. Consequently, ESSReS-PEP-POLMAR provides a solid base for a new generation of excellent scientists in Earth and Environmental Sciences.

Effects of xylitol chewing gum on salivary flow rate, pH, buffering capacity and presence of Streptococcus mutans in saliva.

PubMed

Ribelles Llop, M; Guinot Jimeno, F; Mayné Acién, R; Bellet Dalmau, L J

2010-03-01

The first studies on the use of chewing gum in dentistry were done in the 1970s. The Turku Sugar Studies, carried out between 1970 and 1973, showed the excellent anticaries properties of xylitol chewing gums. Since then, many dentists, particularly in Scandinavian countries, have studied the role of chewing xylitol-sweetened chewing gums as another preventive strategy in the control of dental caries. To compare variations in salivary flow rate, pH, buffering capacity, and levels of Streptococcus mutans in baseline conditions and after chewing paraffin pellets or xylitol chewing gum in children between the ages of 6 and 12 years who eat lunch in a school canteen. The study sample consisted of 90 children divided into 2 study groups, and a control group. The children ate lunch at the canteen of the Escultor Ortells state school in the town of Vila-real (Castellón, Spain). The baseline data recorded in the first phase of the study were compared with the data recorded in the second phase, after 15 minutes of chewing xylitol- sweetened chewing gums or paraffin pellets, depending on the study group. Salivary flow rate was measured by collecting the stimulated saliva in a graduated beaker. Levels of pH were measured using a Cyberscan pH 110 pH meter (Eutech Instruments). CRT buffer strips and the CRT bacteria test (Ivoclar-Vivadent) were used to measure buffering capacity and levels of S. mutans, respectively. The data obtained after sample collection were compared by means of a 1-way analysis of variance using the StatGraphics Plus statistical software package, version 5.0. Statistically significant differences were found (p<.05) when pH, buffering capacity and levels of S. mutans were compared between the 3 groups. Comparison of salivary flow rates revealed no statistically significant differences (p>.05), though salivary flow rates were higher in the groups where gum was chewed. The effect of chewing is essential to the stimulation of salivary flow and the resulting recovery of pH levels and reduction of levels of S. mutans in saliva.

Upper airway biopsy

MedlinePlus

... Otolaryngology – Head and Neck Surgery, The University of Texas Medical School at Houston, Houston, TX. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team. Biopsy Read more Cancer Read more ...

pH regulates genes for flagellar motility, catabolism, and oxidative stress in Escherichia coli K-12.

PubMed

Maurer, Lisa M; Yohannes, Elizabeth; Bondurant, Sandra S; Radmacher, Michael; Slonczewski, Joan L

2005-01-01

Gene expression profiles of Escherichia coli K-12 W3110 were compared as a function of steady-state external pH. Cultures were grown to an optical density at 600 nm of 0.3 in potassium-modified Luria-Bertani medium buffered at pH 5.0, 7.0, and 8.7. For each of the three pH conditions, cDNA from RNA of five independent cultures was hybridized to Affymetrix E. coli arrays. Analysis of variance with an alpha level of 0.001 resulted in 98% power to detect genes showing a twofold difference in expression. Normalized expression indices were calculated for each gene and intergenic region (IG). Differential expression among the three pH classes was observed for 763 genes and 353 IGs. Hierarchical clustering yielded six well-defined clusters of pH profiles, designated Acid High (highest expression at pH 5.0), Acid Low (lowest expression at pH 5.0), Base High (highest at pH 8.7), Base Low (lowest at pH 8.7), Neutral High (highest at pH 7.0, lower in acid or base), and Neutral Low (lowest at pH 7.0, higher at both pH extremes). Flagellar and chemotaxis genes were repressed at pH 8.7 (Base Low cluster), where the cell's transmembrane proton potential is diminished by the maintenance of an inverted pH gradient. High pH also repressed the proton pumps cytochrome o (cyo) and NADH dehydrogenases I and II. By contrast, the proton-importing ATP synthase F1Fo and the microaerophilic cytochrome d (cyd), which minimizes proton export, were induced at pH 8.7. These observations are consistent with a model in which high pH represses synthesis of flagella, which expend proton motive force, while stepping up electron transport and ATPase components that keep protons inside the cell. Acid-induced genes, on the other hand, were coinduced by conditions associated with increased metabolic rate, such as oxidative stress. All six pH-dependent clusters included envelope and periplasmic proteins, which directly experience external pH. Overall, this study showed that (i) low pH accelerates acid consumption and proton export, while coinducing oxidative stress and heat shock regulons; (ii) high pH accelerates proton import, while repressing the energy-expensive flagellar and chemotaxis regulons; and (iii) pH differentially regulates a large number of periplasmic and envelope proteins.

Effect of Porcelain Surface Pretreatments on Composite Resin-Porcelain Shear Bond Strength

DTIC Science & Technology

1991-05-01

Presented to the Faculty of The University of Texas Graduate School of Biomedical Sciences at San Antonio in Partial Fulfillment of the Requirements...Breckner III The University of Texas Graduate School of Biomedical Sciences at San Antonio Supervising Professor: Barry K. Norling, Ph.D. The bond between...necessary to pretreat the porcelain prior to luting. The samples were not, however, hydrated or thermally stressed . Sheth et al. (1988) supported the

Responding to the Challenge of Providing Stronger Research Base for Teacher Education: Research Discourses in the Norwegian National Research School for Teacher Education

ERIC Educational Resources Information Center

Østern, Anna-Lena

2016-01-01

Background and purpose: The purpose of this article is to shed light on how the research projects of 140 PhD candidates in the National Research School for Teacher Education in Norway (NAFOL) respond to the challenges faced by Norwegian teacher education regarding the demand for higher competence and a stronger research base. The concept of NAFOL…

The International Max Planck Research Schools for Molecular Biology and Neurosciences in Gttingen (Germany) as Examples for Joint Doctoral Training by a German University and Its Non-University Partners

ERIC Educational Resources Information Center

Burkhardt, Steffen; Neher, Erwin

2008-01-01

New concepts of higher education have recently been implemented through the MSc/PhD programmes in Molecular Biology and Neurosciences in the International Max Planck Research Schools, due to close cooperation between the University of Gttingen, three Max Planck Institutes and the German Primate Centre. The novel measures include a three stage…

Glycolytic potential and activity of adenosine monophosphate kinase (AMPK), glycogen phosphorylase (GP) and glycogen debranching enzyme (GDE) in steer carcasses with normal (<5.8) or high (>5.9) 24h pH determined in M. longissimus dorsi.

PubMed

Apaoblaza, A; Galaz, A; Strobel, P; Ramírez-Reveco, A; Jeréz-Timaure, N; Gallo, C

2015-03-01

Muscle glycogen concentration (MGC) and lactate (LA), activity of glycogen debranching enzyme (GDE), glycogen phosphorylase (GP) and adenosine monophosphate kinase (AMPK) were determined at 0.5h (T0) and 24h (T24) post-mortem in Longissimus dorsi samples from 38 steers that produced high pH (>5.9) and normal pH (<5.8) carcasses at 24h postmortem. MGC, LA and glycolytic potential were higher (P<0.05) in normal pH carcasses. GDE activity was similar (P>0.05) in both pH categories. GP activity increased between T0 and T24 only in normal pH carcasses. AMPK activity was four times higher in normal pH v/s high pH carcasses, without changing its activity over time. Results reinforce the idea that differences in postmortem glycogenolytic/glycolytic flow in L. dorsi of steers showing normal v/s high muscle pH at 24h, could be explained not only by the higher initial MGC in normal pH carcasses, but also by a high and sustained activity of AMPK and an increased GP activity at 24h postmortem. Copyright © 2014 Elsevier Ltd. All rights reserved.

Determination of the Complex Elastic Moduli of Materials Using A Free- Free Bar Technique

DTIC Science & Technology

1994-03-01

LCDR, Dr. D. L alner 1 Dept. of Physics (Code PH) Naval Postgrdumt School Monterey, CA 93943 10 . Cgimd Ofric. Naval Reserh Labrary ATI’N: Dr. N...Postgraduate School ( fAp~hicbl) Naval Postgraduate School 6c. ADDRESS MclY- $Mae, 02t c7;w 3 7b. ADDRESS (city, MUk and ii? code) Mogntere CA 93943-5=0...Monery CA 93943-5000 Sa. NAME OF FUNDDOISIONS0R]NG G. OFMiCE SYMBOL 9. FUU1ENIICMN IDTFCTONNUMBER ORGANUAT1ON j (If Appkiabie) NSWC. CRANE. NPS

The status of PhD education in economic, social, and administrative sciences between 2005 and 2008.

PubMed

Farley, Joel F; Wang, Chi-Chuan; Blalock, Susan J

2010-09-10

To describe the funding, education, enrollment, and graduation patterns from economic, social, and administrative sciences PhD programs in colleges and schools of pharmacy in the United States. Economic, social, and administrative sciences PhD programs were identified from the American Association of Colleges of Pharmacy (AACP) Web site. A 41-item online survey instrument was sent to the director of graduate studies of each identified program. Only programs offering a PhD degree were included in the study. Of the 26 programs surveyed, 20 (77%) provided useable responses to the survey instrument. Approximately 91% of PhD programs guarantee funding to incoming students with an average commitment of 2.9 years. On average, students were paid a stipend of $18,000 per year for commitments to research and teaching assistantships, each averaging approximately 2 years in length. Programs admitted an average of 3.5 students per year and graduated approximately 85% of entering students. The majority of students are non-US citizens and accept positions in either academic or industrial positions after graduation. Most economic, social, and administrative sciences PhD programs guarantee funding to incoming PhD candidates. Programs offering funding packages significantly below the average may be at a competitive disadvantage. It is unclear whether the number of students graduating from PhD programs is adequate to fulfill academic and industrial needs.

Stereotypic movement disorder

MedlinePlus

... Clinical Assistant Professor of Pediatrics, University of Washington School of Medicine, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team. Child Mental Health Read more NIH MedlinePlus Magazine Read more Health ...

Dr. Rudolph Binion: professor, mentor, psychohistorian.

PubMed

Szaluta, Jacques

2015-01-01

As the title of my paper indicates, Dr. Rudolph Binion was my professor, mentor, and a leading psychohistorian. My paper in memoriam to Rudolph Binion is intended as both a retrospective and an introspective account of my relationship with him, as he had a pivotal influence on me when he was my professor at Columbia University. His help and influence continued after I left graduate school. In my paper I also deal with the enormous stresses of navigating through graduate school, for those students whose goal was to earn the Ph.D. degree. Some examinations were dreaded, For Example The "Examination in Subjects," popularly called the "Oral Exam." The "incubation" period was long indeed, frequently averaging nearly ten years, and it was an ordeal, as the rate of attrition was very high. There is then also the question of "ego strength" and that of "transference" toward the professor. Graduate school is indeed a long and strenuous challenge. I took a seminar in modern French history, a requirement for the Master's degree with Professor Binion, which was consequential for me, as he taught me to be objective in writing history. Professor Binion was a demanding and outstanding teacher.

Use of Combination Thermal Therapy and Radiation in Breast Conserving Treatment of Extensive Intraductal Breast Cancer

DTIC Science & Technology

1994-07-11

Hospital (NEDH); a Harvard Medical School (HMS) affiliated hospital in Boston, Massachusetts. The program director, Goran K. Svensson, Ph.D. is an...Recipes, The Art of Scientific Computing. Cambridge University Press, 1985. 17. Recht, A., Come, S.E., Gelman, R.S., Goldstein, M., Tishler, S., Gore...of Radiation oncology, Harvard Medical School , Boston, Mh 02115 *E.C. Burdette, Dornier Medical System Inc. Champaign, IL 61820 ARTBC at the base of

An Evaluation of the Effectiveness of the Crew Resource Management Programme in Naval Aviation

DTIC Science & Technology

2012-01-01

O’Connor* Centre for Innovation and Structural Change, J.E. Cairnes School of Business and Economics, National University of Ireland, Galway , Ireland E...of Ireland, Galway , as a Research Methodologist in July 2010. He received his PhD in Psychology from the University of Aberdeen, Scotland, in 2002...the US Navy, the Naval Postgraduate School, Naval Air Warfare Center, or the National University of Ireland, Galway . References Alkov, R.A. and

External versus Intuitive Reasoning: The Conjunction Fallacy in Probability Judgment.

DTIC Science & Technology

1983-06-01

tions. Linda is a teacher in elementary school . Linda works in a bookstore and takes Yoga classes. Linda is active in the feminist movement. (F) Linda...sophisticated group consisted of PhD students in the decision science program of the Stanford Busi- ness School , all with several advanced courses in... mind by seemingly incon- sequential cues. There is a contrast worthy of note between the effectiveness of exten- sional cues in the health-survey

Evaluation of the medical student research programme in Norwegian medical schools. A survey of students and supervisors

PubMed Central

Hunskaar, Steinar; Breivik, Jarle; Siebke, Maje; Tømmerås, Karin; Figenschau, Kristian; Hansen, John-Bjarne

2009-01-01

Background The Medical Student Research Programme is a national education and grant scheme for medical students who wish to carry out research in parallel with their studies. The purpose of the programme is to increase recruitment of people with a standard medical degree to medical research. The Research Programme was established in 2002 and underwent a thorough evaluation during the spring of 2007. The evaluation should investigate if the programme had fulfilled its objectives of increased recruitment to medical research, in addition to the students' and supervisors' satisfaction of the programme, and unwanted differences between the universities. Methods Data was collected from students, supervisors and administrative staff via web-based questionnaires. Information about admission, implementation, results achieved and satisfaction was analysed and compared between the four Norwegian medical schools. In addition, the position of the scheme in relation to the national Quality Reform of Higher Education was analysed. Results At the end of 2006, the Medical Student Research Programme had recruited 265 medical students to research. These consisted of 214 active students, 35 who had completed their studies and only 17 who had dropped out. Both students and supervisors were generally very satisfied with the scheme, including the curriculum, the results achieved and the administrative service. The majority of students wanted to continue their research towards a PhD and, of those who had completed the Medical Student Research Programme, practically all had published one or several scientific papers. The survey showed only small differences between the four medical schools, despite their choice of somewhat different solutions in terms of administration and organisation. The Medical Student Research Programme satisfies the majority of the demands of the Quality Reform, however as an integrated research programme aimed at a PhD it presupposes access to PhD courses before the completion of medical studies, as well as the ability to include undergraduate scientific work in a PhD thesis. Conclusion The Medical Student Research Programme has led to an increase in the recruitment of graduated physicians to medical research in Norway. It will only be possible to evaluate whether this in turn will result in a larger number of PhDs in 3–5 years; this will also depend on the access to grants and fellowships. PMID:19602226

Student experimenter stands near middeck lockers in JSC Bldg 9A mockup

NASA Image and Video Library

1991-09-18

S91-47323 (18 Sept 1991) --- Constantine Costes, left, a student experimenter sponsored by United Space Boosters Inc, in Huntsville, Alabama, discusses his student experiment, "Zero-G Rise of Liquid Through Porous Media" with astronauts Ronald J. Grabe (right), STS 42 mission commander; and William Readdy, mission specialist. The student experimenter and crew members are in the Full Fuselage Trainer (FFT) in the Shuttle Mockup and Integration Laboratory. While attending Randolph School, a high school in Huntsville, Alabama, Costes was chosen in the national competition to participate in the Shuttle Student Involvement Program (SSIP). The experiment, contained in a middeck locker, involves the investigation of the effects of gravity on the flow characteristics of a fluid. Both pure capillary and forced flow behavior will be investigated. A ground based experiment was conducted so that gravity influenced data can be compared to that gathered in weightlessness. Costes is now a candidate for a Ph.D in mathematics at Harvard University.

A Conversation with James J. Morgan

NASA Astrophysics Data System (ADS)

Morgan, James J.; Newman, Dianne K.

2015-05-01

In conversation with professor Dianne Newman, Caltech geobiologist, James "Jim" J. Morgan recalls his early days in Ireland and New York City, education in parochial and public schools, and introduction to science in Cardinal Hayes High School, Bronx. In 1950, Jim entered Manhattan College, where he elected study of civil engineering, in particular water quality. Donald O'Connor motivated Jim's future study of O2 in rivers at Michigan, where in his MS work he learned to model O2 dynamics of rivers. As an engineering instructor at Illinois, Jim worked on rivers polluted by synthetic detergents. He chose to focus on chemical studies, seeing it as crucial for the environment. Jim enrolled for PhD studies with Werner Stumm at Harvard, who mentored his research in chemistry of particle coagulation and oxidation processes of Mn(II) and (IV). In succeeding decades, until retirement in 2000, Jim's teaching and research centered on aquatic chemistry; major themes comprised rates of abiotic manganese oxidation on particle surfaces and flocculation of natural water particles, and chemical speciation proved the key.

Effects of medical school selection on student motivation: a PhD thesis report.

PubMed

Wouters, Anouk

2018-02-01

High stakes are involved in student selection, for both medical schools and applicants. This thesis investigated the effects of selection on the medical student population and applicant pool in the Dutch setting. This thesis consists of six papers: two quantitative studies, one qualitative study, two mixed methods studies and one perspective paper based on a review of the literature. (1) Compared with a lottery, selection does not result in a student population with better motivation, engagement and performance, both in the clinical and pre-clinical phases of the study. (2) Selection seems to have a temporary stimulating effect on student motivation through enhancing perceived autonomy, competence and relatedness. (3) Applicants adopt a strategic approach, based on the selection procedure, in their choice of medical school. (4) The description of an applicant's motivation is not a reliable and valid tool to assess motivation during selection. (5) Gaining healthcare experience is crucial for applicants' motivation, but inequalities in access to such experiences can demotivate certain student groups from applying to medical school. (6) The gains yielded from selection compared with a lottery seem to be small. Unintentionally induced self-selection among certain groups of students and biased selection procedures may compromise student diversity. The added value of selection procedures compared with a weighted lottery for admitting students to medical school is questionable. Students are generally motivated and perform well, irrespective of how they enrolled in medical school. Selection yields only small gains, while student diversity may be hampered.

32 CFR 242.9 - Academic, intellectual, and personal requirements for admission to advanced standing.

Code of Federal Regulations, 2011 CFR

2011-07-01

... schools will be eligible for transfer. (c) Individuals who have received the D.D.S., D.M.D., Ph.D., D.O.... Advanced standing applicants are required to have taken the Medical College Admission Test. ...

32 CFR 242.9 - Academic, intellectual, and personal requirements for admission to advanced standing.

Code of Federal Regulations, 2013 CFR

2013-07-01

... schools will be eligible for transfer. (c) Individuals who have received the D.D.S., D.M.D., Ph.D., D.O.... Advanced standing applicants are required to have taken the Medical College Admission Test. ...

32 CFR 242.9 - Academic, intellectual, and personal requirements for admission to advanced standing.

Code of Federal Regulations, 2014 CFR

2014-07-01

... schools will be eligible for transfer. (c) Individuals who have received the D.D.S., D.M.D., Ph.D., D.O.... Advanced standing applicants are required to have taken the Medical College Admission Test. ...

32 CFR 242.9 - Academic, intellectual, and personal requirements for admission to advanced standing.

Code of Federal Regulations, 2012 CFR

2012-07-01

... schools will be eligible for transfer. (c) Individuals who have received the D.D.S., D.M.D., Ph.D., D.O.... Advanced standing applicants are required to have taken the Medical College Admission Test. ...

A Broader View of Immunotherapies | Center for Cancer Research

Cancer.gov

Fresh out of graduate school at Wayne State University in Michigan in 1985, Bernard Fox, Ph.D., landed a coveted fellowship with Steven Rosenberg, M.D., just as the first patients were being treated with cell-based immunotherapies at NCI.

Monitoring the Environment: The Use of Electronic Meters and Chemical or Bacteriological Tests.

ERIC Educational Resources Information Center

Crellin, J. R.; Tranter, J.

1978-01-01

A review is given of electronic environmental meters available for use in schools. Included are conductivity, oxygen, pH, and temperature meters. Chemical test papers and kits for use in environmental studies are included. (BB)

Reflection-mode micro-spherical fiber-optic probes for in vitro real-time and single-cell level pH sensing.

PubMed

Yang, Qingbo; Wang, Hanzheng; Lan, Xinwei; Cheng, Baokai; Chen, Sisi; Shi, Honglan; Xiao, Hai; Ma, Yinfa

2015-02-01

pH sensing at the single-cell level without negatively affecting living cells is very important but still a remaining issue in the biomedical studies. A 70 μm reflection-mode fiber-optic micro-pH sensor was designed and fabricated by dip-coating thin layer of organically modified aerogel onto a tapered spherical probe head. A pH sensitive fluorescent dye 2', 7'-Bis (2-carbonylethyl)-5(6)-carboxyfluorescein (BCECF) was employed and covalently bonded within the aerogel networks. By tuning the alkoxide mixing ratio and adjusting hexamethyldisilazane (HMDS) priming procedure, the sensor can be optimized to have high stability and pH sensing ability. The in vitro real-time sensing capability was then demonstrated in a simple spectroscopic way, and showed linear measurement responses with a pH resolution up to an average of 0.049 pH unit within a narrow, but biological meaningful pH range of 6.12-7.81. Its novel characterizations of high spatial resolution, reflection mode operation, fast response and high stability, great linear response within biological meaningful pH range and high pH resolutions, make this novel pH probe a very cost-effective tool for chemical/biological sensing, especially within the single cell level research field.

Reflection-mode micro-spherical fiber-optic probes for in vitro real-time and single-cell level pH sensing

PubMed Central

Yang, Qingbo; Wang, Hanzheng; Lan, Xinwei; Cheng, Baokai; Chen, Sisi; Shi, Honglan; Xiao, Hai; Ma, Yinfa

2014-01-01

pH sensing at the single-cell level without negatively affecting living cells is very important but still a remaining issue in the biomedical studies. A 70 μm reflection-mode fiber-optic micro-pH sensor was designed and fabricated by dip-coating thin layer of organically modified aerogel onto a tapered spherical probe head. A pH sensitive fluorescent dye 2′, 7′-Bis (2-carbonylethyl)-5(6)-carboxyfluorescein (BCECF) was employed and covalently bonded within the aerogel networks. By tuning the alkoxide mixing ratio and adjusting hexamethyldisilazane (HMDS) priming procedure, the sensor can be optimized to have high stability and pH sensing ability. The in vitro real-time sensing capability was then demonstrated in a simple spectroscopic way, and showed linear measurement responses with a pH resolution up to an average of 0.049 pH unit within a narrow, but biological meaningful pH range of 6.12–7.81. Its novel characterizations of high spatial resolution, reflection mode operation, fast response and high stability, great linear response within biological meaningful pH range and high pH resolutions, make this novel pH probe a very cost-effective tool for chemical/biological sensing, especially within the single cell level research field. PMID:25530670

Nicotine Absorption from Smokeless Tobacco Modified to Adjust pH

PubMed Central

Pickworth, Wallace B.; Rosenberry, Zachary R.; Gold, Wyatt; Koszowski, Bartosz

2014-01-01

Introduction Nicotine delivery from smokeless tobacco (ST) products leads to addiction and the use of ST causes pathology that is associated with increased initiation of cigarette smoking. The rapid delivery of nicotine from ST seems to be associated with the pH of the aqueous suspension of the products - high pH is associated with high nicotine absorption. However, early studies compared nicotine absorption from different commercial products that not only differed in pH but in flavoring, nicotine content, and in format-pouches and loose tobacco. Methods The present study compared nicotine absorption from a single unflavored referent ST product (pH 7.7) that was flavored with a low level of wintergreen (2 mg/g) and the pH was amended to either high (8.3) or low (5.4) pH with sodium carbonate or citric acid, respectively. Results In a within-subject clinical study, the higher pH products delivered more nicotine. No significant differences were seen between perceived product strengths and product experience in all conditions. Heart rate increased by 4 to 6 beats per minute after the high pH flavored and the un-amended product but did not change after the low pH flavored product. Conclusions These results indicate that pH is a primary determinant of buccal nicotine absorption. The role of flavoring and other components of ST products in nicotine absorption remain to be determined. PMID:25530912

Investigation of pH and Temperature Profiles in the GI Tract of Fasted Human Subjects Using the Intellicap(®) System.

PubMed

Koziolek, Mirko; Grimm, Michael; Becker, Dieter; Iordanov, Ventzeslav; Zou, Hans; Shimizu, Jeff; Wanke, Christoph; Garbacz, Grzegorz; Weitschies, Werner

2015-09-01

Gastrointestinal (GI) pH and temperature profiles under fasted-state conditions were investigated in two studies with each 10 healthy human subjects using the IntelliCap(®) system. This telemetric drug delivery device enabled the determination of gastric emptying time, small bowel transit time, and colon arrival time by significant pH and temperature changes. The study results revealed high variability of GI pH and transit times. The gastric transit of IntelliCap(®) was characterized by high fluctuations of the pH with mean values ranging from pH 1.7 to pH 4.7. Gastric emptying was observed after 7-202 min (median: 30 min). During small bowel transit, which had a duration of 67-532 min (median: 247 min), pH values increased slightly from pH 5.9-6.3 in proximal parts to pH 7.4-7.8 in distal parts. Colonic pH conditions were characterized by values fluctuating mainly between pH 5 and pH 8. The pH profiles and transit times described in this work are highly relevant for the comprehension of drug delivery of solid oral dosage forms comprising ionizable drugs and excipients with pH-dependent solubility. © 2014 Wiley Periodicals, Inc. and the American Pharmacists Association.

The NURSING-Positive Recruitment Arabic Model (NURS-P.R.A.M.): A Mixed Methods Study.

PubMed

Tawash, Eman; Cowman, Seamus

2018-06-12

To identify factors influencing high school students' choice of nursing and explore strategic interventions to promote nursing as a career in the Arab region. This study forms part of a PhD thesis, conducted in Bahrain, in a healthcare environment with a high dependence on expatriate nurses to maintain nursing services. However, in attracting local candidates to study nursing, the public image of nursing in the Middle East must be improved by implementing strategies that are sensitive to the Arabic culture. A mixed methods approach incorporating quantitative and qualitative dimensions. Data were collected between 2012-2015 using self-administered questionnaires, semi-structured interviews, focus groups and written narratives. The study sample included high school students, parents, career guidance counsellors and nursing students. A one-group pre-test post-test design was used to introduce a nursing recruitment intervention to high school students. SPSS was used to analyse quantitative data. Colaizzi's (1978) and Krueger's (1994) frameworks were applied to analyse the qualitative data. It is proposed that the public perceptions of Arab people about nursing may be grounded in strong cultural influences and any efforts to improve the enrolment and retention of local nurses should consider enhancing the social values of the nursing profession. The NURSING-Positive Recruitment Arabic Model incorporates essential elements which will guide nursing recruitment in the Arabic cultures. The study findings reflect certain issues similar to the core international literature on nursing recruitment, however there are fundamental issues particular to the Arab region, which must be included in the development of a nursing recruitment strategy for Arabic nursing. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

DISTRIBUTION OF DERMATOPHYTES FROM SOILS OF URBAN AND RURAL AREAS OF CITIES OF PARAIBA STATE, BRAZIL

PubMed Central

Pontes, Zélia Braz Vieira da Silva; de Oliveira, Aurylene Carlos; Guerra, Felipe Queiroga Sarmento; Pontes, Luiz Renato de Araújo; dos Santos, Jozemar Pereira

2013-01-01

SUMMARY The dermatophytes, keratinophilic fungi, represent important microorganisms of the soil microbiota, where there are cosmopolitan species and others with restricted geographic distribution. The aim of this study was to broaden the knowledge about the presence of dermatophytes in soils of urban (empty lots, schools, slums, squares, beaches and homes) and rural areas and about the evolution of their prevalence in soils of varying pH in cities of the four mesoregions of Paraiba State, Brazil. Soil samples were collected from 31 cities of Paraiba State. Of 212 samples, 62% showed fungal growth, particularly those from the Mata Paraibana mesoregion (43.5%), which has a tropical climate, hot and humid. Soil pH varied from 4.65 to 9.06, with 71% of the growth of dermatophytes occurring at alkaline pH (7.02 - 9.06) (ρ = 0.000). Of 131 strains isolated, 57.3% were geophilic species, particularly Trichophyton terrestre (31.3%) and Mycrosporum gypseum (21.4%). M. nanum and T. ajelloi were isolated for the first time in Paraiba State. The zoophilic species identified were T. mentagrophytes var. mentagrophytes (31.3 %) and T. verrucosum (7.6 %), and T. tonsurans was isolated as an anthropophilic species. The soils of urban areas including empty lots, schools, slums and squares of cities in the mesoregions of Paraiba State were found to be the most suitable reservoirs for almost all dermatophytes; their growth may have been influenced by environmental factors, soils with residues of human and/or animal keratin and alkaline pH. PMID:24213189

Distribution of dermatophytes from soils of urban and rural areas of cities of Paraiba State, Brazil.

PubMed

Pontes, Zélia Braz Vieira da Silva; Oliveira, Aurylene Carlos de; Guerra, Felipe Queiroga Sarmento; Pontes, Luiz Renato de Araújo; Santos, Jozemar Pereira dos

2013-01-01

The dermatophytes, keratinophilic fungi, represent important microorganisms of the soil microbiota, where there are cosmopolitan species and others with restricted geographic distribution. The aim of this study was to broaden the knowledge about the presence of dermatophytes in soils of urban (empty lots, schools, slums, squares, beaches and homes) and rural areas and about the evolution of their prevalence in soils of varying pH in cities of the four mesoregions of Paraiba State, Brazil. Soil samples were collected from 31 cities of Paraiba State. Of 212 samples, 62% showed fungal growth, particularly those from the Mata Paraibana mesoregion (43.5%), which has a tropical climate, hot and humid. Soil pH varied from 4.65 to 9.06, with 71% of the growth of dermatophytes occurring at alkaline pH (7.02 - 9.06) (ρ = 0.000). Of 131 strains isolated, 57.3% were geophilic species, particularly Trichophyton terrestre (31.3%) and Mycrosporum gypseum (21.4%). M. nanum and T. ajelloi were isolated for the first time in Paraiba State. The zoophilic species identified were T. mentagrophytes var. mentagrophytes (31.3 %) and T. verrucosum (7.6 %), and T. tonsurans was isolated as an anthropophilic species. The soils of urban areas including empty lots, schools, slums and squares of cities in the mesoregions of Paraiba State were found to be the most suitable reservoirs for almost all dermatophytes; their growth may have been influenced by environmental factors, soils with residues of human and/or animal keratin and alkaline pH.

Superlattice photonic crystal as broadband solar absorber for high temperature operation.

PubMed

Rinnerbauer, Veronika; Shen, Yichen; Joannopoulos, John D; Soljačić, Marin; Schäffler, Friedrich; Celanovic, Ivan

2014-12-15

A high performance solar absorber using a 2D tantalum superlattice photonic crystal (PhC) is proposed and its design is optimized for high-temperature energy conversion. In contrast to the simple lattice PhC, which is limited by diffraction in the short wavelength range, the superlattice PhC achieves solar absorption over broadband spectral range due to the contribution from two superposed lattices with different cavity radii. The superlattice PhC geometry is tailored to achieve maximum thermal transfer efficiency for a low concentration system of 250 suns at 1500 K reaching 85.0% solar absorptivity. In the high concentration case of 1000 suns, the superlattice PhC absorber achieves a solar absorptivity of 96.2% and a thermal transfer efficiency of 82.9% at 1500 K, amounting to an improvement of 10% and 5%, respectively, versus the simple square lattice PhC absorber. In addition, the performance of the superlattice PhC absorber is studied in a solar thermophotovoltaic system which is optimized to minimize absorber re-emission by reducing the absorber-to-emitter area ratio and using a highly reflective silver aperture.

Predictors of Student Productivity in Biomedical Graduate School Applications

PubMed Central

O’Connell, Anna B.; Cook, Jeanette G.

2017-01-01

Many US biomedical PhD programs receive more applications for admissions than they can accept each year, necessitating a selective admissions process. Typical selection criteria include standardized test scores, undergraduate grade point average, letters of recommendation, a resume and/or personal statement highlighting relevant research or professional experience, and feedback from interviews with training faculty. Admissions decisions are often founded on assumptions that these application components correlate with research success in graduate school, but these assumptions have not been rigorously tested. We sought to determine if any application components were predictive of student productivity measured by first-author student publications and time to degree completion. We collected productivity metrics for graduate students who entered the umbrella first-year biomedical PhD program at the University of North Carolina at Chapel Hill from 2008–2010 and analyzed components of their admissions applications. We found no correlations of test scores, grades, amount of previous research experience, or faculty interview ratings with high or low productivity among those applicants who were admitted and chose to matriculate at UNC. In contrast, ratings from recommendation letter writers were significantly stronger for students who published multiple first-author papers in graduate school than for those who published no first-author papers during the same timeframe. We conclude that the most commonly used standardized test (the general GRE) is a particularly ineffective predictive tool, but that qualitative assessments by previous mentors are more likely to identify students who will succeed in biomedical graduate research. Based on these results, we conclude that admissions committees should avoid over-reliance on any single component of the application and de-emphasize metrics that are minimally predictive of student productivity. We recommend continual tracking of desired training outcomes combined with retrospective analysis of admissions practices to guide both application requirements and holistic application review. PMID:28076439

Children and grief

MedlinePlus

... Clinical Assistant Professor of Pediatrics, University of Washington School of Medicine, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team. Related MedlinePlus Health Topics Bereavement Child Mental Health Browse the Encyclopedia A.D.A.M., ...

Senior Leadership: Succession Effects on Organizational Performance

DTIC Science & Technology

2013-12-10

Ricardo A. Herrera , Ph.D. , Seminar Leader John Paganini, COL , Director, School of Advanced Military Studies Hank Arnold, COL...periods. Team Number of Successions Average Team Standing (16 teams) 1921-41 1951-58 Both 1921-41 1951-58 Both Phillies Giants Cardinals Braves

Tested Demonstrations.

ERIC Educational Resources Information Center

Gilbert, George L., Ed.

1983-01-01

Presents background information and procedures for producing sequential color reactions. With proper selection of pH indicator dyes, most school colors can be produced after mixing colorless solutions. Procedures for producing white/purple and red/white/blue colors are outlined. Also outlines preparation of 2, 4, 2', 4',…

High-Pressure-High-Temperature Processing Reduces Maillard Reaction and Viscosity in Whey Protein-Sugar Solutions.

PubMed

Avila Ruiz, Geraldine; Xi, Bingyan; Minor, Marcel; Sala, Guido; van Boekel, Martinus; Fogliano, Vincenzo; Stieger, Markus

2016-09-28

The aim of the study was to determine the influence of pressure in high-pressure-high-temperature (HPHT) processing on Maillard reactions and protein aggregation of whey protein-sugar solutions. Solutions of whey protein isolate containing either glucose or trehalose at pH 6, 7, and 9 were treated by HPHT processing or conventional high-temperature (HT) treatments. Browning was reduced, and early and advanced Maillard reactions were retarded under HPHT processing at all pH values compared to HT treatment. HPHT induced a larger pH drop than HT treatments, especially at pH 9, which was not associated with Maillard reactions. After HPHT processing at pH 7, protein aggregation and viscosity of whey protein isolate-glucose/trehalose solutions remained unchanged. It was concluded that HPHT processing can potentially improve the quality of protein-sugar-containing foods, for which browning and high viscosities are undesired, such as high-protein beverages.

Reduction on the anaerobic biological activity inhibition caused by heavy metals and sulphates in effluents through chemical precipitation with soda and lime.

PubMed

Alves, L de Carvalho; Cammarota, M C; De França, F P

2006-12-01

The School of Chemistry Environmental Technology Laboratory generates 43.4 1 of effluent with low pH (0.7) and high contents of COD (1908 mgO2 l(-1)), phenol (132.1 mg l(-1)), sulfate (36700 mg l(-1)) and heavy metals (28.2 mg Hg l(-1); 82.1 mg Cr(total) l(-1); 30.8 mg Cu l(-1); 57.4 mg Fe(total) l(-1); 16.2 mg Al l(-1)) weekly. These data show that this effluent presents high toxicity for biological treatment, with a physical-chemical step being necessary before a biological step. Preliminary studies showed that the most toxic constituents of the effluent were sulfate, phenol and total chromium. In this work, a chemical precipitation step with sodium hydroxide or lime was evaluated for the toxicity reduction on anaerobic microbial consortium. These experiments were carried out with increasing concentrations of alkalis in the effluent in order to obtain pH initial values of 8-12. Similar results were obtained for COD (15-28%), turbidity (95-98%), phenol (13-24%) and total chromium (99.8-99.9%) removals in each condition studied with soda or lime. Sulfate was only removed by precipitation with lime, obtaining reductions from 84 to 88%. The toxicity on the anaerobic sludge was studied employing specific methanogenic activity (SMA) analysis of raw and treated effluent (after chemical precipitation step). The SMA experiments showed that chemical precipitation at pH 8 reduces the toxic effect of the effluent on anaerobic microbial consortium three times (with soda) and thirteen times (with lime). These results indicate that precipitation with lime is more efficient at toxicity removal, however the produced sludge volume is around two times higher than that produced with soda.

Doctoral programs to train future leaders in clinical and translational science.

PubMed

Switzer, Galen E; Robinson, Georgeanna F W B; Rubio, Doris M; Fowler, Nicole R; Kapoor, Wishwa N

2013-09-01

Although the National Institutes of Health (NIH) has made extensive investments in educational programs related to clinical and translational science (CTS), there has been no systematic investigation of the number and characteristics of PhD programs providing training to future leaders in CTS. The authors undertook to determine the number of institutions that, having had received NIH-funded Clinical and Translational Science Awards (CTSAs), currently had or were developing PhD programs in CTS; to examine differences between programs developed before and after CTSA funding; and to provide detailed characteristics of new programs. In 2012, CTS program leaders at the 60 CTSA-funded institutions completed a cross-sectional survey focusing on four key domains related to PhD programs in CTS: program development and oversight; students; curriculum and research; and milestones. Twenty-two institutions had fully developed PhD programs in CTS, and 268 students were earning PhDs in this new field; 13 institutions were planning PhD programs. New programs were more likely to have fully developed PhD competencies and more likely to include students in medical school, students working only on their PhD, students working on a first doctoral degree, and students working in T1 translational research. They were less likely to include physicians and students working in clinical or T2 research. Although CTS PhD programs have similarities, they also vary in their characteristics and management of students. This may be due to diversity in translational science itself or to the relative infancy of CTS as a discipline.

Doctoral Programs to Train Future Leaders in Clinical and Translational Science

PubMed Central

Switzer, Galen E.; Robinson, Georgeanna F.W.B.; Rubio, Doris M.; Fowler, Nicole R.; Kapoor, Wishwa N.

2013-01-01

Purpose Although the National Institutes of Health (NIH) has made extensive investments in educational programs related to clinical and translational science (CTS), there has been no systematic investigation of the number and characteristics of PhD programs providing training to future leaders in CTS. The authors undertook to determine the number of institutions that, having had received NIH-funded Clinical and Translational Science Awards (CTSAs), currently had or were developing PhD programs in CTS; to examine differences between programs developed before and after CTSA funding; and to provide detailed characteristics of new programs. Method In 2012, CTS program leaders at the 60 CTSA-funded institutions completed a cross-sectional survey focusing on four key domains related to PhD programs in CTS: program development and oversight; students; curriculum and research; and milestones. Results Twenty-two institutions had fully developed PhD programs in CTS, and 268 students were earning a PhD in this new field; 13 institutions were planning a PhD program. New programs were more likely to have fully developed PhD competencies and more likely to include students in medical school, students working only on their PhD, students working on a first doctoral degree, and students working in T1 translational research. They were less likely to include physicians and students working in clinical or T2 research. Conclusions Although CTS PhD programs have similarities, they also vary in their characteristics and management of students. This may be due to diversity in translational science itself or to the relative infancy of CTS as a discipline. PMID:23899901

Acid and Base Stress and Transcriptomic Responses in Bacillus subtilis▿†

PubMed Central

Wilks, Jessica C.; Kitko, Ryan D.; Cleeton, Sarah H.; Lee, Grace E.; Ugwu, Chinagozi S.; Jones, Brian D.; BonDurant, Sandra S.; Slonczewski, Joan L.

2009-01-01

Acid and base environmental stress responses were investigated in Bacillus subtilis. B. subtilis AG174 cultures in buffered potassium-modified Luria broth were switched from pH 8.5 to pH 6.0 and recovered growth rapidly, whereas cultures switched from pH 6.0 to pH 8.5 showed a long lag time. Log-phase cultures at pH 6.0 survived 60 to 100% at pH 4.5, whereas cells grown at pH 7.0 survived <15%. Cells grown at pH 9.0 survived 40 to 100% at pH 10, whereas cells grown at pH 7.0 survived <5%. Thus, growth in a moderate acid or base induced adaptation to a more extreme acid or base, respectively. Expression indices from Affymetrix chip hybridization were obtained for 4,095 protein-encoding open reading frames of B. subtilis grown at external pH 6, pH 7, and pH 9. Growth at pH 6 upregulated acetoin production (alsDS), dehydrogenases (adhA, ald, fdhD, and gabD), and decarboxylases (psd and speA). Acid upregulated malate metabolism (maeN), metal export (czcDO and cadA), oxidative stress (catalase katA; OYE family namA), and the SigX extracytoplasmic stress regulon. Growth at pH 9 upregulated arginine catabolism (roc), which generates organic acids, glutamate synthase (gltAB), polyamine acetylation and transport (blt), the K+/H+ antiporter (yhaTU), and cytochrome oxidoreductases (cyd, ctaACE, and qcrC). The SigH, SigL, and SigW regulons were upregulated at high pH. Overall, greater genetic adaptation was seen at pH 9 than at pH 6, which may explain the lag time required for growth shift to high pH. Low external pH favored dehydrogenases and decarboxylases that may consume acids and generate basic amines, whereas high external pH favored catabolism-generating acids. PMID:19114526

Acid and base stress and transcriptomic responses in Bacillus subtilis.

PubMed

Wilks, Jessica C; Kitko, Ryan D; Cleeton, Sarah H; Lee, Grace E; Ugwu, Chinagozi S; Jones, Brian D; BonDurant, Sandra S; Slonczewski, Joan L

2009-02-01

Acid and base environmental stress responses were investigated in Bacillus subtilis. B. subtilis AG174 cultures in buffered potassium-modified Luria broth were switched from pH 8.5 to pH 6.0 and recovered growth rapidly, whereas cultures switched from pH 6.0 to pH 8.5 showed a long lag time. Log-phase cultures at pH 6.0 survived 60 to 100% at pH 4.5, whereas cells grown at pH 7.0 survived <15%. Cells grown at pH 9.0 survived 40 to 100% at pH 10, whereas cells grown at pH 7.0 survived <5%. Thus, growth in a moderate acid or base induced adaptation to a more extreme acid or base, respectively. Expression indices from Affymetrix chip hybridization were obtained for 4,095 protein-encoding open reading frames of B. subtilis grown at external pH 6, pH 7, and pH 9. Growth at pH 6 upregulated acetoin production (alsDS), dehydrogenases (adhA, ald, fdhD, and gabD), and decarboxylases (psd and speA). Acid upregulated malate metabolism (maeN), metal export (czcDO and cadA), oxidative stress (catalase katA; OYE family namA), and the SigX extracytoplasmic stress regulon. Growth at pH 9 upregulated arginine catabolism (roc), which generates organic acids, glutamate synthase (gltAB), polyamine acetylation and transport (blt), the K(+)/H(+) antiporter (yhaTU), and cytochrome oxidoreductases (cyd, ctaACE, and qcrC). The SigH, SigL, and SigW regulons were upregulated at high pH. Overall, greater genetic adaptation was seen at pH 9 than at pH 6, which may explain the lag time required for growth shift to high pH. Low external pH favored dehydrogenases and decarboxylases that may consume acids and generate basic amines, whereas high external pH favored catabolism-generating acids.

A comparative study on oxidative stress response in the hepatopancreas and midgut of the white shrimp Litopenaeus vannamei under gradual changes to low or high pH environment.

PubMed

Han, Si-Yin; Wang, Meng-Qiang; Wang, Bao-Jie; Liu, Mei; Jiang, Ke-Yong; Wang, Lei

2018-05-01

White shrimp Litopenaeus vannamei were reared under conditions of gradual changes to a low pH (gradual-low pH, 6.65-8.20) or a high pH (gradual-high pH, 8.20-9.81) versus a normal pH environment (8.14-8.31) during a 28-day period. Survival of shrimp, and ROS production, antioxidant responses and oxidative damage in the hepatopancreas and midgut were investigated. Consequently, shrimp enhanced MnSOD, GPx, and Hsp70 transcripts as early defense mechanism in the hepatopancreas and midgut to scavenge excessive ROS during short-term (≤ 7 days) gradual-low and high pH stress. Meanwhile, the hepatopancreas was more sensitive to ROS than midgut because of earlier ROS production increase, antioxidant response and oxidative damage. Then, suppressed antioxidant response in the hepatopancreas and midgut of shrimp suggested a loss of antioxidant regulatory capacity caused by aggravated oxidative damage after long-term (≥ 14 days) gradual-high pH stress, leading to continuous death. However, enhanced GPx, GST, and Hsp70 transcripts in the hepatopancreas and midgut might be long-term(≥ 14 days) antioxidant adaptation mechanism of shrimp to gradual-low pH stress, which could prevent further ROS perturbation and weaken oxidative damage to achieve a new immune homeostasis, contributing to stable survival rate. Therefore, we have a few insights that it is necessary to protect hepatopancreas for controlling shrimp death under gradual-high pH stress. Copyright © 2018 Elsevier Ltd. All rights reserved.

Rhodamine-based fluorescent probe for direct bio-imaging of lysosomal pH changes.

PubMed

Shi, Xue-Lin; Mao, Guo-Jiang; Zhang, Xiao-Bing; Liu, Hong-Wen; Gong, Yi-Jun; Wu, Yong-Xiang; Zhou, Li-Yi; Zhang, Jing; Tan, Weihong

2014-12-01

Intracellular pH plays a pivotal role in various biological processes. In eukaryotic cells, lysosomes contain numerous enzymes and proteins exhibiting a variety of activities and functions at acidic pH (4.5-5.5), and abnormal variation in the lysosomal pH causes defects in lysosomal function. Thus, it is important to investigate lysosomal pH in living cells to understand its physiological and pathological processes. In this work, we designed a one-step synthesized rhodamine derivative (RM) with morpholine as a lysosomes tracker, to detect lysosomal pH changes with high sensitivity, high selectivity, high photostability and low cytotoxicity. The probe RM shows a 140-fold fluorescence enhancement over a pH range from 7.4 to 4.5 with a pKa value of 5.23. Importantly, RM can detect the chloroquine-induced lysosomal pH increase and monitor the dexamethasone-induced lysosomal pH changes during apoptosis in live cells. All these features demonstrate its value of practical application in biological systems. Copyright © 2014 Elsevier B.V. All rights reserved.

Validity of HydraTrend reagent strips for the assessment of hydration status.

PubMed

Abbey, Bryce M; Heelan, Kate A; Brown, Gregory A; Bartee, Rodrick T

2014-09-01

Hydration is used by athletic governing organizations for weight class eligibility. The measurement of urine specific gravity (USG) as a measure of hydration by reagent strips is a controversial issue. The purpose of this study was to determine the validity of HydraTrend reagent strips that facilitate the correction of USG for alkaline urine samples against refractometry for the assessment of USG. Fifty-one participants (33 males, age = 22.3 ± 1.3 years; 18 females, age = 22.4 ± 1.2 years) provided 84 urine samples. The samples were tested for USG using refractometry and reagent strips and for pH using reagent strips and a digital pH meter. Strong correlation coefficients were found between refractometry and reagent strips for USG (rs(82) = 0.812, p < 0.01) and between reagent strips and pH meter for pH (rs(82) = 0.939, p < 0.01). It was observed that false negative results for National Collegiate Athletic Association (NCAA) requirements (fail refractometry with USG >1.020, pass reagent strips with USG ≤1.020) occurred 39% (33/84) of the time and false negative results for National Federation of State High School Association (NFHS) requirements (fail refractometry with USG >1.025, pass reagent strips with USG ≤1.025) occurred 14% (12/84) of the time. There were no false positives (pass refractometry and fail reagent strips) for NCAA or NFHS requirements. These data show that refractometry and reagent strips have strong positive correlations. However, the risk of a false negative result leading to incorrect certification of euhydration status outweighs the benefits of the HydraTrend reagent strips for the measurement of USG.

Low Medium pH Value Enhances Anthocyanin Accumulation in Malus Crabapple Leaves

PubMed Central

Tian, Ji; Jin, Kaina; Yao, Yuncong

2014-01-01

Anthocyanin is a critical factor involved in coloration of plant tissues, but the mechanism how medium pH values affect anthocyanin accumulation in woody plants is unknown. We analyzed anthocyanin composition and the expression of elements encoding anthocyanin and flavonols biosynthesis underlying different medium pH values by using three different leave color type cultivars. HPLC analysis demonstrated that high medium pH values treatment induced a dramatic decrease in the concentration of cyaniding in crabapple leaves. Conversely, the high medium pH values induced up-regulation of the content of flavones and flavonols, suggesting that low pH treatment-induced anthocyanin accumulation. Quantitative real time PCR experiment showed the expression level of anthocyanidin synthase (McANS) and uridine diphosphate glucose flavonoid 3-O-glucosyltransferase (McUFGT) was up-regulated by low pH values treatment, and high medium pH value treatment up-regulate the transcription level of flavonol synthase (McFLS). Meanwhile, several MYB TFs have been suggested in the regulation of pH responses. These results strongly indicate that the low pH treatment-induced anthocyanin accumulation is mediated by the variation of mRNA transcription of the anthocyanin biosynthetic genes. PMID:24914811

Building on the Success of Increasing Diversity in the Geosciences: A Bridging Program From Middle School to College

NASA Astrophysics Data System (ADS)

Kovacs, T.; Robinson, D.; Suleiman, A.; Maggi, B.

2004-12-01

A bridging program to increase the diversity in the geosciences was created at Hampton University (HU) to inspire underrepresented minorities to pursue an educational path that advances them towards careers in the geosciences. Three objectives were met to achieve this goal. First, we inspired a diverse population of middle and high school students outside of the classroom by providing an after school geoscience club, a middle school geoscience summer enrichment camp, and a research/mentorship program for high school students. Second, we helped fill the need for geoscience curriculum content requested of science teachers who work primarily with underrepresented middle school populations by providing a professional development workshop at HU led by geoscience professors, teachers, and science educators. Third, we built on the successful atmospheric sciences research and active Ph.D. program by developing our geoscience curriculum including the formation of a new space, earth, and atmospheric sciences minor. All workshops, camps, and clubs have been full or nearly full each year despite restrictions on participants repeating any of the programs. The new minor has 11 registered undergraduates and the total number of students in these classes has been increasing. Participants of all programs gave the quality of the program good ratings and participant perceptions and knowledge improved throughout the programs based on pre-, formative, and summative assessments. The ultimate goal is to increase the number of degrees granted to underrepresented minorities in the geosciences. We have built a solid foundation with our minor that prepares students for graduate degrees in the geosciences and offer a graduate degree in physics with a concentration in the atmospheric sciences. However, it's from the geoscience pipeline that students will come into our academic programs. We expect to continue to develop these formal and informal education programs to increase our reputation and utilize the network of schools with which we have built relationships to recruit underrepresented minority students into our academic programs. We also plan to continue to enhance our undergraduate minor and graduate degree programs to build a self-sustaining graduate degree-granting program in the geosciences.

Molecular gated-AlGaN/GaN high electron mobility transistor for pH detection.

PubMed

Ding, Xiangzhen; Yang, Shuai; Miao, Bin; Gu, Le; Gu, Zhiqi; Zhang, Jian; Wu, Baojun; Wang, Hong; Wu, Dongmin; Li, Jiadong

2018-04-18

A molecular gated-AlGaN/GaN high electron mobility transistor has been developed for pH detection. The sensing surface of the sensor was modified with 3-aminopropyltriethoxysilane to provide amphoteric amine groups, which would play the role of receptors for pH detection. On modification with 3-aminopropyltriethoxysilane, the transistor exhibits good chemical stability in hydrochloric acid solution and is sensitive for pH detection. Thus, our molecular gated-AlGaN/GaN high electron mobility transistor acheived good electrical performances such as chemical stability (remained stable in hydrochloric acid solution), good sensitivity (37.17 μA/pH) and low hysteresis. The results indicate a promising future for high-quality sensors for pH detection.

Online PH measurement technique in seawater desalination

NASA Astrophysics Data System (ADS)

Wang, Haibo; Wu, Kaihua; Hu, Shaopeng

2009-11-01

The measurement technology of pH is essential in seawater desalination. Glass electrode is the main pH sensor in seawater desalination. Because the internal impedance of glass electrode is high and the signal of pH sensor is easy to be disturbed, a signal processing circuit with high input impedance was designed. Because of high salinity of seawater and the characteristic of glass electrode, ultrasonic cleaning technology was used to online clean pH sensor. Temperature compensation was also designed to reduce the measurement error caused by variety of environment temperature. Additionally, the potential drift of pH sensor was analyzed and an automatic calibration method was proposed. In order to online monitor the variety of pH in seawater desalination, three operating modes were designed. The three modes are online monitoring mode, ultrasonic cleaning mode and auto-calibration mode. The current pH in seawater desalination was measured and displayed in online monitoring mode. The cleaning process of pH sensor was done in ultrasonic cleaning mode. The calibration of pH sensor was finished in auto-calibration mode. The result of experiments showed that the measurement technology of pH could meet the technical requirements for desalination. The glass electrode could be promptly and online cleaned and its service life was lengthened greatly.

The sensitivity of particle pH to NH3: Can high NH3 cause London Fog conditions?

NASA Astrophysics Data System (ADS)

Weber, R. J.; Guo, H.; Nenes, A.

2017-12-01

High ammonia emissions from agriculture or other sources have been suggested to elevate ambient particle pH levels to near neutral acidity (pH=7), a condition that promotes rapid SO2 oxidation by NO2 to form aerosol sulfate concentration consistent with "London fog" levels. This mechanism has been used to explain pollution haze events in China. Predicted pH for locations in the US and Europe show fine particles are highly acidic with pH typically less than 2. The results are consistent with measured ammonia and nitric acid gas-particle partitioning, validating predicted pH levels. Using these data sets from representative sites around the world we conduct a thermodynamic analysis of aerosol pH and its sensitivity to ammonia levels. We find that particle pH, regardless of ammonia levels, is always acidic even for the unusually high ammonia levels found in highly polluted Asian cities, Beijing (pH=4.5) and Xi'an (pH=5), locations where sulfate production from NOx is proposed. These results indicate that sulfur dioxide oxidation through a NO2-mediated pathway is not likely in China, nor any other region of the world (e.g., US, Mediterranean) since the fine aerosol is consistently acidic. The mildly acidic conditions would, however, permit rapid oxidation of sulfur dioxide through transition metal chemistry. The limited alkalinity from the carbonate buffer in dust and seasalt can provide the only likely set of conditions where NO2-mediated oxidation of SO2 outcompetes with other well-established pathways.

76 FR 23599 - Findings of Research Misconduct

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-27

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary Findings of Research Misconduct... Research Integrity (ORI) has taken final action in the following case: Vipul Bhrigu, PhD, University of... School (UMMS) and additional analysis conducted by the Office of Research Integrity (ORI) during its...

76 FR 47589 - Findings of Research Misconduct

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-05

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary Findings of Research Misconduct... Research Integrity (ORI) has taken final action in the following case: Sheng Wang, PhD, Boston University School of Medicine Cancer Research Center: Based on the Respondent's acceptance of ORI's research...

Chem I Supplement: Emphasis on Acids and Bases

ERIC Educational Resources Information Center

Journal of Chemical Education Staff

1977-01-01

Provides supplementary notes on acids and bases suitable for secondary school chemistry instruction, including acidity in solid and natural waters, acidity balance in body chemistry, acid and basic foods, pH values of common fluids, examples of drugs, and commercial preparation of nitric acid. (SL)

Cancer Bulletin Profile: In Their Own Words: Raju Kucherlapati, Ph.D. - TCGA

Cancer.gov

Dr. Raju Kucherlapati, the Paul C. Cabot Professor of Genetics at Harvard Medical School, speaks about cancer genetics and genomics, specifically the Cancer Genome Atlas project and the tools that personalized medicine may provide to detect, treat, and prevent cancer.

Female condoms

MedlinePlus

... of Gynecology and Obstetrics at Johns Hopkins University School of Medicine, Baltimore, MD. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team. Birth Control Read more NIH MedlinePlus Magazine Read more Health ...

A Doctorate--Necessary but Not Sufficient.

ERIC Educational Resources Information Center

Perry, Shannon E.

1982-01-01

The author argues that nursing faculty need more than a Ph.D. to be considered scholars in the field. A discussion of technical versus professional education in nursing is presented along with an examination of faculty rules for promotion and tenure in schools of nursing. (CT)

PH-sensitive dispersion of carbon nanotubes by myoglobin

NASA Astrophysics Data System (ADS)

Nie, Haiyu; Shen, Ganni; Sun, Junlin; Zhang, Tao

2017-03-01

A facile and effective method of dispersion of double-walled carbon nanotubes (DWNTs) was developed. At appropriate pH value and sonication, myoglobin helps the solubilization of DWNTs. The product is a pH-sensitive dispersion, which remains in a highly dispersed state at pH<3.0 and pH>10.0. This approach can be used to disperse DWNTs in scale. A reversible conversion of the highly dispersed state to the aggregated state could be observed by changing the pH value. This feature holds great promise for the development of pH sensors.

Natural Fatigue Crack Initiation and Detection in High Quality Spur Gears

DTIC Science & Technology

2012-06-01

Natural Fatigue Crack Initiation and Detection in High Quality Spur Gears by David “Blake” Stringer, Ph.D., Kelsen E. LaBerge, Ph.D., Cory...0383 June 2012 Natural Fatigue Crack Initiation and Detection in High Quality Spur Gears David “Blake” Stringer and Ph.D., Kelsen E. LaBerge...Quality Spur Gears 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) David “Blake” Stringer, Ph.D., Kelsen E

Controlling self-assembly of diphenylalanine peptides at high pH using heterocyclic capping groups.

PubMed

Martin, Adam D; Wojciechowski, Jonathan P; Robinson, Andrew B; Heu, Celine; Garvey, Christopher J; Ratcliffe, Julian; Waddington, Lynne J; Gardiner, James; Thordarson, Pall

2017-03-08

Using small angle neutron scattering (SANS), it is shown that the existence of pre-assembled structures at high pH for a capped diphenylalanine hydrogel is controlled by the selection of N-terminal heterocyclic capping group, namely indole or carbazole. At high pH, changing from a somewhat hydrophilic indole capping group to a more hydrophobic carbazole capping group results in a shift from a high proportion of monomers to self-assembled fibers or wormlike micelles. The presence of these different self-assembled structures at high pH is confirmed through NMR and circular dichroism spectroscopy, scanning probe microscopy and cryogenic transmission electron microscopy.

Self-collimating photonic crystal polarization beam splitter.

PubMed

Zabelin, V; Dunbar, L A; Le Thomas, N; Houdré, R; Kotlyar, M V; O'Faolain, L; Krauss, T F

2007-03-01

We present theoretical and experimental results of a polarization splitter device that consists of a photonic crystal (PhC) slab, which exhibits a large reflection coefficient for TE and a high transmission coefficient for TM polarization. The slab is embedded in a PhC tile operating in the self-collimation mode. Embedding the polarization-discriminating slab in a PhC with identical lattice symmetry suppresses the in-plane diffraction losses at the PhC-non-PhC interface. The optimization of the PhC-non-PhC interface is thereby decoupled from the optimization of the polarizing function. Transmissions as high as 35% for TM- and 30% for TE-polarized light are reported.

pH measurement and a rational and practical pH control strategy for high throughput cell culture system.

PubMed

Zhou, Haiying; Purdie, Jennifer; Wang, Tongtong; Ouyang, Anli

2010-01-01

The number of therapeutic proteins produced by cell culture in the pharmaceutical industry continues to increase. During the early stages of manufacturing process development, hundreds of clones and various cell culture conditions are evaluated to develop a robust process to identify and select cell lines with high productivity. It is highly desirable to establish a high throughput system to accelerate process development and reduce cost. Multiwell plates and shake flasks are widely used in the industry as the scale down model for large-scale bioreactors. However, one of the limitations of these two systems is the inability to measure and control pH in a high throughput manner. As pH is an important process parameter for cell culture, this could limit the applications of these scale down model vessels. An economical, rapid, and robust pH measurement method was developed at Eli Lilly and Company by employing SNARF-4F 5-(-and 6)-carboxylic acid. The method demonstrated the ability to measure the pH values of cell culture samples in a high throughput manner. Based upon the chemical equilibrium of CO(2), HCO(3)(-), and the buffer system, i.e., HEPES, we established a mathematical model to regulate pH in multiwell plates and shake flasks. The model calculates the required %CO(2) from the incubator and the amount of sodium bicarbonate to be added to adjust pH to a preset value. The model was validated by experimental data, and pH was accurately regulated by this method. The feasibility of studying the pH effect on cell culture in 96-well plates and shake flasks was also demonstrated in this study. This work shed light on mini-bioreactor scale down model construction and paved the way for cell culture process development to improve productivity or product quality using high throughput systems. Copyright 2009 American Institute of Chemical Engineers

Importance of water quality in container plant production

Treesearch

John M. Ruter

2013-01-01

High substrate pH is a major problem for producers of container-grown plants and seedlings. The primary cause of high substrate pH is irrigation water with high alkalinity. Alkalinity is defined as the capacity of water to neutralize acids. Some alkalinity in irrigation water is beneficial as it serves as a buffer to large swings in pH levels, but high alkalinity in...

Community-Based Soil Quality Assessment As a Tool for Designing an Urban Green Infrastructure Network to Manage Runoff.

NASA Astrophysics Data System (ADS)

Klimas, C.; Montgomery, J.

2014-12-01

Green infrastructure (GI) may be the most practical approach for reducing contaminated runoff, providing ecosystem services, mitigating food deserts and creating community open spaces in urban areas. This project was funded by the USEPA's People-Prosperity-Planet (P3) program and was a partnership between a team of DePaul University undergraduates (the P3 team) and high school interns (Green Teens) and staff from the Gary Comer Youth Center (GCYC). GCYC is located in a low-income African-American community on Chicago's south side characterized by high crime, abandoned buildings, lack of green space and a food desert. The overaching project goal was to develop a network of Green Teens qualified to conduct soil quality assessment using USDA-NRCS protocols in order to let them develop GI plans to minimize storm water runoff and contaminant loadings, improve community and environmental health, and provide more equitable access to green space. Working with a USDA-ARS soil scientist from Washington State University, the P3 team conducted soil quality assessment on 116 soil samples collected among four abandoned residential lots owned by GCYC. Analytes included infiltration, bulk density, texture, pH, conductivity, aggregate stability, available nutrients, and total and bioavailable (PBET) lead. Soil pH on all lots is greater than 8.0, are low in organic matter, have little microbial respiration activity, are enriched in available phosphorus, and have average total lead values ranging from 24-2,700 mg/kg. PBET lead was less than 40% on most lots. Regardless, these soils will need to be remediated by adding carbon-rich materials such as biosolids prior to GI installation. Students enrolled in a landscape design course at DePaul developed 3-D models representing potential GI designs for one of the vacant lots that include strategies for immobilizing heavy metals, reducing runoff, and which are tied into an educational module for neighborhood school children.

Assessment of the suitability of Durafet-based sensors for pH measurement in dynamic estuarine environments

NASA Astrophysics Data System (ADS)

Gonski, Stephen F.; Cai, Wei-Jun; Ullman, William J.; Joesoef, Andrew; Main, Christopher R.; Pettay, D. Tye; Martz, Todd R.

2018-01-01

The suitability of the Honeywell Durafet to the measurement of pH in productive, high-fouling, and highly-turbid estuarine environments was investigated at the confluence of the Murderkill Estuary and Delaware Bay (Delaware, USA). Three different flow configurations of the SeapHOx sensor equipped with a Honeywell Durafet and its integrated internal (Ag/AgCl reference electrode containing a 4.5 M KCl gel liquid junction) and external (solid-state chloride ion selective electrode, Cl-ISE) reference electrodes were deployed for four periods between April 2015 and September 2016. In this environment, the Honeywell Durafet proved capable of making high-resolution and high-frequency pH measurements on the total scale between pH 6.8 and 8.4. Natural pH fluctuations of >1 pH unit were routinely captured over a range of timescales. The sensor pH collected between May and August 2016 using the most refined SeapHOx configuration exhibited good agreement with multiple sets of independently measured reference pH values. When deployed in conjunction with rigorous discrete sampling and calibration schemes, the sensor pH had a root-mean squared error ranging between 0.011 and 0.036 pH units across a wide range of salinity relative to both pHT calculated from measured dissolved inorganic carbon and total alkalinity and pHNBS measured with a glass electrode corrected to pHT at in situ conditions. The present work demonstrates the viability of the Honeywell Durafet to the measurement of pH to within the weather-level precision defined by the Global Ocean Acidification Observing Network (GOA-ON, ≤ 0.02 pH units) as a part of future estuarine CO2 chemistry studies undertaken in dynamic environments.

Discovering and Developing Successful Cardiovascular Therapeutics: A Conversation With James N. Topper, MD, PhD.

PubMed

Topper, James N; Rutherford, John D

2016-11-15

Dr James (also known as Jamie) N. Topper, MD, PhD, serves as Managing General Partner at Frazier Healthcare Partners, where he leads the Life Science Venture practice. In 2011, and 2016, he was named to the Midas List of leading venture capitalists, and, in 2013, he was recognized by Forbes as one of the top 10 healthcare investors. He has >25 years of experience working with entrepreneurs to found and build successful therapeutics-focused companies. Dr Topper holds a BS from the University of Michigan. He received an MD and PhD (in biophysics) from Stanford University School of Medicine. He completed postgraduate training in internal medicine and cardiovascular disease at the Brigham and Women's Hospital in Boston and is board certified in both disciplines. © 2016 American Heart Association, Inc.

Economic Analysis of Earning a PhD Degree After Completion of a PharmD Degree

PubMed Central

Murawski, Matthew M.

2011-01-01

Objective To determine the net present value (NPV) and internal rate of return (IRR) for earning a doctor of philosophy (PhD) degree and pursuing careers commonly associated with that degree after completion of a doctor of pharmacy (PharmD) degree compared to entering pharmacy practice directly upon completion of the PharmD degree. Methods Income profiles were constructed based on 2008 annual salary data. NPV and IRR were calculated for careers resulting from the PhD degree and compared to those of the practicing community pharmacist. Trends in IRR also were examined across career paths from 1982 to 2008. A priori assumptions were developed and sensitivity analyses were conducted. Results The NPVs for all careers associated with the PhD degree were negative compared to that of the practicing community pharmacist. IRRs ranged from -1.4% to 1.3% for PhD careers. Longitudinal examination of IRRs indicated a negative trend from 1982 to 2008. Conclusions Economic financial incentives for PharmD graduates to pursue graduate school are lacking. The study illustrates the need to consider financial incentives when developing recruitment methods for PharmD graduates to pharmacy graduate programs. PMID:21451769

Effect of pH and glucose on cultured human peritoneal mesothelial cells.

PubMed

Shao, J C; Yorioka, N; Nishida, Y; Yamakido, M

1999-08-01

We investigated the effects of various pH and glucose concentrations on the growth of human peritoneal mesothelial cells and on coagulation and fibrinolytic factors. Cells were cultured at various pH values in Ham's F-12 medium containing 1.0% foetal calf serum and supplemented with D-glucose or D-mannitol at various concentrations. After 4-48 h, cell proliferation and 3H-thymidine incorporation were determined. Coagulation and fibrinolytic factors were measured after 48 h. Glucose caused concentration-dependent inhibition of cell growth at all pH values, but the deleterious effect of low pH on cell proliferation was faster and stronger than that of high glucose. At a similar osmolality, mannitol caused less inhibition of cell proliferation than glucose. There was a glucose concentration-dependent increase of thrombin-antithrombin III complex production at all pH values. At pH 5.2, tissue-type plasminogen activator production was far lower than at higher pH values, and production of the plasminogen activator inhibitor showed a glucose concentration-dependent increase. At pH 6.5 or 7.3, however, the plasminogen activator inhibitor production decreased and tissue-type plasminogen activator production increased in a glucose concentration-dependent manner. Low pH and/or high glucose culture medium had an inhibitory effect on peritoneal mesothelial cells, with the effect of high glucose being partially related to hyperosmolality. These cells may modulate peritoneal coagulant and fibrinolytic activity, with the balance between coagulation and fibrinolysis being disturbed by low pH and/or high glucose.

Dental plaque pH variation with regular soft drink, diet soft drink and high energy drink: an in vivo study.

PubMed

Jawale, Bhushan Arun; Bendgude, Vikas; Mahuli, Amit V; Dave, Bhavana; Kulkarni, Harshal; Mittal, Simpy

2012-03-01

A high incidence of dental caries and dental erosion associated with frequent consumption of soft drinks has been reported. The purpose of this study was to evaluate the pH response of dental plaque to a regular, diet and high energy drink. Twenty subjects were recruited for this study. All subjects were between the ages of 20 and 25 and had at least four restored tooth surfaces present. The subjects were asked to refrain from brushing for 48 hours prior to the study. At baseline, plaque pH was measured from four separate locations using harvesting method. Subjects were asked to swish with 15 ml of the respective soft drink for 1 minute. Plaque pH was measured at the four designated tooth sites at 5, 10 and 20 minutes intervals. Subjects then repeated the experiment using the other two soft drinks. pH was minimum for regular soft drink (2.65 ± 0.026) followed by high energy drink (3.39 ± 0.026) and diet soft drink (3.78 ± 0.006). The maximum drop in plaque pH was seen with regular soft drink followed by high energy drink and diet soft drink. Regular soft drink possesses a greater acid challenge potential on enamel than diet and high energy soft drinks. However, in this clinical trial, the pH associated with either soft drink did not reach the critical pH which is expected for enamel demineralization and dissolution.

Global and public health core competencies for nursing education: A systematic review of essential competencies.

PubMed

Clark, Megan; Raffray, Marie; Hendricks, Kristin; Gagnon, Anita J

2016-05-01

Nurses are learning and practicing in an increasingly global world. Both nursing schools and nursing students are seeking guidance as they integrate global health into their learning and teaching. This systematic review is intended to identify the most common global and public health core competencies found in the literature and better inform schools of nursing wishing to include global health content in their curricula. Systematic review. An online search of CINAHL and Medline databases, as well as, inclusion of pertinent gray literature was conducted for articles published before 2013. Relevant literature for global health (GH) and public and community health (PH/CH) competencies was reviewed to determine recommendations of both competencies using a combination of search terms. Studies must have addressed competencies as defined in the literature and must have been pertinent to GH or PH/CH. The databases were systematically searched and after reading the full content of the included studies, key concepts were extracted and synthesized. Twenty-five studies were identified and resulted in a list of 14 global health core competencies. These competencies are applicable to a variety of health disciplines, but particularly can inform the efforts of nursing schools to integrate global health concepts into their curricula. Copyright © 2016 Elsevier Ltd. All rights reserved.

Innovations in the En Route Care of Combat Casualties

DTIC Science & Technology

2014-01-01

Beekley, A. C., Martin , M. J., Nelson, T., Grathwohl, K. W., Griffi th, M., Beilman, G., & Holcomb, J. B. (2010). Continuous noninvasive tissue...Medicine Occupational Health Program University of Maryland School of Medicine Baltimore, MD Petra Goodman, PhD, WHNP-BC COL (Ret), U.S. Army

75 FR 77641 - Findings of Research Misconduct

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-13

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary Findings of Research Misconduct... Research Integrity (ORI) has taken final action in the following case: Sagar S. Mungekar, PhD, New York... University School of Medicine (NYUSOM) and the Office of Research Integrity (ORI) found that Sagar S...

78 FR 2956 - Marine Mammals; File No. 17005

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-15

... Peter Rogers, Ph.D., Georgia Institute of Technology, Woodruff School of Mechanical Engineering, Atlanta...-invasively determining the low frequency elastic properties of cetacean head tissues. The ultrasound system... researchers to: (1) Determine any short term changes in soft tissue elasticity if an animal dies during the...

Jeffery G. Linger | NREL

Science.gov Websites

development Metabolic engineering Fundamental molecular biology and genetics Education Ph.D., Biochemistry and Molecular Genetics, University of Colorado School of Medicine, 2006 B.S., Environmental, Population, and . Specifically, Linger uses molecular biology techniques to assess the feasibility of converting the

Birth control pills - overview

MedlinePlus

... of Gynecology and Obstetrics at Johns Hopkins University School of Medicine, Baltimore, MD. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team. Birth Control Read more NIH MedlinePlus Magazine Read more Health ...

Hardness does not affect the physiological responses of wild and domestic strains of diploid and triploid rainbow trout Oncorhynchus mykiss to short-term exposure to pH 9.5.

PubMed

Thompson, W A; Rodela, T M; Richards, J G

2016-08-01

This study examined the effects of water hardness on the physiological responses associated with high pH exposure in multiple strains of diploid and triploid rainbow trout Oncorhynchus mykiss. To accomplish this, three wild strains and one domesticated strain of diploid and triploid O. mykiss were abruptly transferred from control soft water (City of Vancouver dechlorinated tap water; pH 6·7; [CaCO3 ] < 17·9 mg l(-1) ) to control soft water (handling control), high pH soft water (pH 9·5; [CaCO3 ] < 17·9 mg l(-1) ), or high pH hard water (pH 9·5; [CaCO3 ] = 320 mg l(-1) ) followed by sampling at 24 h for physiological measurements. There was a significant effect of ploidy on loss of equilibrium (LOE) over the 24 h exposure, with only triploid O. mykiss losing equilibrium at high pH in both soft and hard water. Furthermore, exposure to pH 9·5 resulted in significant decreases in plasma sodium and chloride, and increases in plasma and brain ammonia with no differences between soft and hard water. There was no significant effect of strain on LOE, but there were significant differences between strains in brain ammonia and plasma cortisol. Overall, there were no clear protective effects of hardness on high pH exposure in these strains of O. mykiss. © 2016 The Fisheries Society of the British Isles.

[Primary hyperaldosteronism: problems of diagnostic approaches].

PubMed

Widimský, Jiří

2015-05-01

Primary hyperaldosteronism (PH) is common cause of endocrine/secondary hypertension with autonomous aldosterone overproduction by adrenal cortex. PH is typically characterized by hypertension, hypokalemia, high plasma aldosterone/renin ratio, high aldosterone, suppressed renin and nonsupressibilty of aldosterone during confirmatory tests. Diagnosis of PH can be difficult since hypokalemia is found only in 50 % of cases and measurement of the parameters of renin-angiotensin-aldosterone system can be influenced by several factors. Morphological dia-gnosis requires in majority of cases adrenal venous sampling. Early diagnostic and therapeutic measures are very important due to high prevalence of PH and potential cure. Patients with suspicion to PH should be investigated in experienced hypertensive centers due to relatively difficult laboratory and morphological diagnostic approaches.

The New Aphrodite school on Disasters Food and Poverty organized by CIMA Research Foundation and University of Genova

NASA Astrophysics Data System (ADS)

Boni, G.

2009-04-01

CIMA is a Research Foundation which aim is to advance science and engineering in environmentally related fields, focusing on public health and safety, civil protection and the preservation of terrestrial and water-related ecosystems. This aim is accomplished through scientific research, technology transfer and high level training services. Here we present the "New Aphrodite school on Disasters Food and Poverty" jointly managed by CIMA Foundation, and the University of Genova. The school is organized to provide to international students, professionals and government officials, mainly from poor or developing countries, formation for the management, prediction and prevention of natural and man made disasters. The expertise of the teachers, mainly CIMA's researchers, comes from a long term support of CIMA Foundation to the Italian Civil Protection in developing the advanced national system for risk prediction, prevention and management. The school is organized in two levels. The first level includes an international master of science degree in "Environmental Engineering: Sustainable Development and Risk Management", which classes are given in English, and a master for professional and government officials in "Disasters, food and poverty". The second level includes an international Ph.D. programme in "Information sciences and technologies for system monitoring and environmental risk management". Short training courses for international government official are periodically organized. At present the school is organizing short courses for officials of Civil Protections of Venezuela, Barbados and Mozambique. The philosophy underlying the teaching activities is to promote a multi-disciplinary approach to disaster mitigation, prevention and prediction. Special focus is on the potential of high-tech low-cost technologies for rapid communication and disaster monitoring, such as satellite based technologies. Such technologies are seen as the best way to support the development of autonomous capacities in developing countries, with affordable investment costs, and to improve globally the understanding of the phenomena leading to disasters.

Outdoor cultures of Chlorella pyrenoidosa in the effluent of anaerobically digested activated sludge: The effects of pH and free ammonia.

PubMed

Tan, Xiao-Bo; Zhang, Ya-Lei; Yang, Li-Bin; Chu, Hua-Qiang; Guo, Jun

2016-01-01

A freshwater algae Chlorella pyrenoidosa was cultured outdoors using anaerobically digested activated sludge effluent. The effects of pH variations were evaluated. The coupled pH variations and free ammonia toxicity significantly affected the algal growth, lipids accumulation and contamination control during every season. The free ammonia toxicity at high pH levels actually inhibited the algal growth. Compared to an optimal algal growth at a pH of 5.7-6.5, biomass productivity at a high pH of 8.3-8.8 was reduced by 67.15±6.98%, 54.39±6.42% and 83.63±5.71% in the spring, fall and summer, respectively. When the pH rose above 9.1-9.6, algae were unable to grow in the wastewater. However, high pH levels reduced contamination (e.g., bacteria and microalgae grazers) and triggered lipids accumulation in algal cells. These findings suggest that pH control strategies are essential for this type of algal wastewater system, where ammonia is the dominant nitrogen source. Copyright © 2015 Elsevier Ltd. All rights reserved.

High-Resolution pH Imaging of Living Bacterial Cells To Detect Local pH Differences

PubMed Central

Morimoto, Yusuke V.; Kami-ike, Nobunori; Miyata, Tomoko; Kawamoto, Akihiro; Kato, Takayuki

2016-01-01

ABSTRACT Protons are utilized for various biological activities such as energy transduction and cell signaling. For construction of the bacterial flagellum, a type III export apparatus utilizes ATP and proton motive force to drive flagellar protein export, but the energy transduction mechanism remains unclear. Here, we have developed a high-resolution pH imaging system to measure local pH differences within living Salmonella enterica cells, especially in close proximity to the cytoplasmic membrane and the export apparatus. The local pH near the membrane was ca. 0.2 pH unit higher than the bulk cytoplasmic pH. However, the local pH near the export apparatus was ca. 0.1 pH unit lower than that near the membrane. This drop of local pH depended on the activities of both transmembrane export components and FliI ATPase. We propose that the export apparatus acts as an H+/protein antiporter to couple ATP hydrolysis with H+ flow to drive protein export. PMID:27923921

The Shampoo pH can Affect the Hair: Myth or Reality?

PubMed Central

Gavazzoni Dias, Maria Fernanda Reis; de Almeida, Andréia Munck; Cecato, Patricia Makino Rezende; Adriano, Andre Ricardo; Pichler, Janine

2014-01-01

Aim: Dermatologists most frequently prescribe shampoos for the treatment of hair shed and scalp disorders. Prescription of hair care products is often focused on improving scalp hair density, whereas the over-the-counter products focus on hair damage prevention. Little is taught in medical schools about the hair cosmetics, so that the prescriptions are based only on the treatment of the scalp and usually disregards the hair fiber health. Materials and Methods: In this work, we review the current literature about the mode of action of a low-pH shampoo regarding the hair shaft's health and analyze the pH of 123 shampoos of international brands. Results: All shampoo pH values ranged from 3.5 to 9.0. 38.21% of all 123 shampoos presented a pH ≤ 5.5 (IC: 29.9–47%) and 61.78% presented a pH > 5.5. 26 anti-dandruff shampoos were analyzed. About 19.23% presented pH ≤ 5.5.(IC: 7.4–37.6%). 80.77% of all anti-dandruffs shampoos presented a pH > 5.5. The dermatological shampoo group (n = 19) presented 42.10% with pH ≤ 5.5 (IC: 21.8–64.6%), and 57.90% with pH > 5.5. Among the commercial (popular) products (n = 96), 34.37% presented pH ≤ 5.5 (IC: 25.4–44.3%) and 65.62% presented pH > 5.5. 15 professional products (used in hair salons) were analyzed, of which 75% had a pH ≤ 5.5 (IC: 18–65, 4%), and 25% had a pH > 5.5. 100% of the children's shampoos presented a pH > 5.5. Conclusions: Alkaline pH may increase the negative electrical charge of the hair fiber surface and, therefore, increase friction between the fibers. This may lead to cuticle damage and fiber breakage. It is a reality and not a myth that lower pH of shampoos may cause less frizzing for generating less negative static electricity on the fiber surface. Interestingly, only 38% of the popular brand shampoos against 75% of the salons shampoos presented a pH ≤ 5.0. Pediatric shampoos had the pH of 7.0 because of the “no-tear” concept. There is no standardized value for the final pH. The authors believe that it is important to reveal the pH value on the shampoo label, but studies are needed to establish the best pH range for both the scalp and the hair fiber's health. PMID:25210332

The Shampoo pH can Affect the Hair: Myth or Reality?

PubMed

Gavazzoni Dias, Maria Fernanda Reis; de Almeida, Andréia Munck; Cecato, Patricia Makino Rezende; Adriano, Andre Ricardo; Pichler, Janine

2014-07-01

Dermatologists most frequently prescribe shampoos for the treatment of hair shed and scalp disorders. Prescription of hair care products is often focused on improving scalp hair density, whereas the over-the-counter products focus on hair damage prevention. Little is taught in medical schools about the hair cosmetics, so that the prescriptions are based only on the treatment of the scalp and usually disregards the hair fiber health. In this work, we review the current literature about the mode of action of a low-pH shampoo regarding the hair shaft's health and analyze the pH of 123 shampoos of international brands. All shampoo pH values ranged from 3.5 to 9.0. 38.21% of all 123 shampoos presented a pH ≤ 5.5 (IC: 29.9-47%) and 61.78% presented a pH > 5.5. 26 anti-dandruff shampoos were analyzed. About 19.23% presented pH ≤ 5.5.(IC: 7.4-37.6%). 80.77% of all anti-dandruffs shampoos presented a pH > 5.5. The dermatological shampoo group (n = 19) presented 42.10% with pH ≤ 5.5 (IC: 21.8-64.6%), and 57.90% with pH > 5.5. Among the commercial (popular) products (n = 96), 34.37% presented pH ≤ 5.5 (IC: 25.4-44.3%) and 65.62% presented pH > 5.5. 15 professional products (used in hair salons) were analyzed, of which 75% had a pH ≤ 5.5 (IC: 18-65, 4%), and 25% had a pH > 5.5. 100% of the children's shampoos presented a pH > 5.5. Alkaline pH may increase the negative electrical charge of the hair fiber surface and, therefore, increase friction between the fibers. This may lead to cuticle damage and fiber breakage. It is a reality and not a myth that lower pH of shampoos may cause less frizzing for generating less negative static electricity on the fiber surface. Interestingly, only 38% of the popular brand shampoos against 75% of the salons shampoos presented a pH ≤ 5.0. Pediatric shampoos had the pH of 7.0 because of the "no-tear" concept. There is no standardized value for the final pH. The authors believe that it is important to reveal the pH value on the shampoo label, but studies are needed to establish the best pH range for both the scalp and the hair fiber's health.

PROMISE: Maryland's Alliance for Graduate Education and the Professoriate enhances recruitment and retention of underrepresented minority graduate students.

PubMed

Tull, Renetta G; Rutledge, Janet C; Carter, Frances D; Warnick, Jordan E

2012-11-01

PROMISE: Maryland's Alliance for Graduate Education and the Professoriate (AGEP), sponsored by the National Science Foundation, is a consortium that is designed to increase the numbers of underrepresented minority (URM) PhDs in science, technology, engineering, and mathematics fields who will pursue academic careers. A strength of PROMISE is its alliance infrastructure that connects URM graduate students on different campuses through centralized programming for the three research universities in Maryland: the University of Maryland Baltimore County (the lead institution in the alliance), the University of Maryland College Park, and the University of Maryland Baltimore (UMB). PROMISE initiatives cover graduate student recruitment, retention, community building, PhD completion, and transition to careers.Although it is not a fellowship, PROMISE offers professional development and skill-building programs that provide academic and personal support for URM students on all three campuses. PROMISE on UMB's campus includes the School of Medicine, which sponsors tricampus programs that promote health and wellness to accompany traditional professional development programs. PROMISE uniquely and atypically includes a medical school within its alliance. The PROMISE programs serve as interventions that reduce isolation and facilitate degree completion among diverse students on each campus. This article describes details of the PROMISE AGEP and presents suggestions for replicating professional development programs for URMs in biomedical, MD/master's, and MD/PhD programs on other campuses.

Earth and Space Science Ph.D. Class of 2003 Report released

NASA Astrophysics Data System (ADS)

Keelor, Brad

AGU and the American Geological Institute (AGI) released on 26 July an employment study of 180 Earth and space science Ph.D. recipients who received degrees from U.S. universities in 2003. The AGU/AGI survey asked graduates about their education and employment, efforts to find their first job after graduation, and experiences in graduate school. Key results from the study include: The vast majority (87%) of 2003 graduates found work in the Earth and space sciences, earning salaries commensurate with or slightly higher than 2001 and 2002 salary averages. Most (64%) graduates were employed within academia (including postdoctoral appointments), with the remainder in government (19%), industry (10%), and other (7%) sectors. Most graduates were positive about their employment situation and found that their work was challenging, relevant, and appropriate for someone with a Ph.D. The percentage of Ph.D. recipients accepting postdoctoral positions (58%) increased slightly from 2002. In contrast, the fields of physics and chemistry showed significant increases in postdoctoral appointments for Ph.D.s during the same time period. As in previous years, recipients of Ph.D.s in the Earth, atmospheric, and ocean sciences (median age of 32.7 years) are slightly older than Ph.D. recipients in most other natural sciences (except computer sciences), which is attributed to time taken off between undergraduate and graduate studies. Women in the Earth, atmospheric,and ocean sciences earned 33% of Ph.D.s in the class of 2003, surpassing the percentage of Ph.D.s earned by women in chemistry (32%) and well ahead of the percentage in computer sciences (20%), physics (19%), and engineering (17%). Participation of other underrepresented groups in the Earth, atmospheric, and ocean sciences remained extremely low.

Net Income of Pharmacy Faculty Compared to Community and Hospital Pharmacists

PubMed Central

Gatwood, Justin; Spivey, Christina A.; Dickey, Susan E.

2016-01-01

Objective. To compare the net cumulative income of community pharmacists, hospital pharmacists, and full-time pharmacy faculty members (residency-trained or with a PhD after obtaining a PharmD) in pharmacy practice, medicinal chemistry, pharmaceutics, pharmacology, and social and administrative sciences. Methods. Markov modeling was conducted to calculate net projected cumulative earnings of career paths by estimating the costs of education, including the costs of obtaining degrees and student loans. Results. The economic model spanned 49 years, from ages 18 to 67 years. Earning a PharmD and pursuing an academic career resulted in projected net cumulative lifetime earnings ranging from approximately $4.7 million to $6.3 million. A pharmacy practice faculty position following public pharmacy school and one year of residency resulted in higher net cumulative income than community pharmacy. Faculty members with postgraduate year 1 (PGY1) training also had higher net income than other faculty and hospital pharmacy career paths, given similar years of prepharmacy education and type of pharmacy school attended. Faculty members with either a PharmD or PhD in the pharmacology discipline may net as much as $5.9 million and outpace all other PhD graduates by at least $75 000 in lifetime earnings. Projected career earnings of postgraduate year 2 (PGY2) trained faculty and PharmD/PhD faculty members were lower than those of community pharmacists. Findings were more variable when comparing pharmacy faculty members and hospital pharmacists. Conclusion. With the exception of PGY1 trained academic pharmacists, faculty projected net cumulative incomes generally lagged behind community pharmacists, likely because of delayed entry into the job market as a result of advanced training/education. However, nonsalary benefits such as greater flexibility and autonomy may enhance the desirability of academic pharmacy as a career path. PMID:27756925

Net Income of Pharmacy Faculty Compared to Community and Hospital Pharmacists.

PubMed

Chisholm-Burns, Marie A; Gatwood, Justin; Spivey, Christina A; Dickey, Susan E

2016-09-25

Objective. To compare the net cumulative income of community pharmacists, hospital pharmacists, and full-time pharmacy faculty members (residency-trained or with a PhD after obtaining a PharmD) in pharmacy practice, medicinal chemistry, pharmaceutics, pharmacology, and social and administrative sciences. Methods. Markov modeling was conducted to calculate net projected cumulative earnings of career paths by estimating the costs of education, including the costs of obtaining degrees and student loans. Results. The economic model spanned 49 years, from ages 18 to 67 years. Earning a PharmD and pursuing an academic career resulted in projected net cumulative lifetime earnings ranging from approximately $4.7 million to $6.3 million. A pharmacy practice faculty position following public pharmacy school and one year of residency resulted in higher net cumulative income than community pharmacy. Faculty members with postgraduate year 1 (PGY1) training also had higher net income than other faculty and hospital pharmacy career paths, given similar years of prepharmacy education and type of pharmacy school attended. Faculty members with either a PharmD or PhD in the pharmacology discipline may net as much as $5.9 million and outpace all other PhD graduates by at least $75 000 in lifetime earnings. Projected career earnings of postgraduate year 2 (PGY2) trained faculty and PharmD/PhD faculty members were lower than those of community pharmacists. Findings were more variable when comparing pharmacy faculty members and hospital pharmacists. Conclusion. With the exception of PGY1 trained academic pharmacists, faculty projected net cumulative incomes generally lagged behind community pharmacists, likely because of delayed entry into the job market as a result of advanced training/education. However, nonsalary benefits such as greater flexibility and autonomy may enhance the desirability of academic pharmacy as a career path.

Controlling self-assembly of diphenylalanine peptides at high pH using heterocyclic capping groups

PubMed Central

Martin, Adam D.; Wojciechowski, Jonathan P.; Robinson, Andrew B.; Heu, Celine; Garvey, Christopher J.; Ratcliffe, Julian; Waddington, Lynne J.; Gardiner, James; Thordarson, Pall

2017-01-01

Using small angle neutron scattering (SANS), it is shown that the existence of pre-assembled structures at high pH for a capped diphenylalanine hydrogel is controlled by the selection of N-terminal heterocyclic capping group, namely indole or carbazole. At high pH, changing from a somewhat hydrophilic indole capping group to a more hydrophobic carbazole capping group results in a shift from a high proportion of monomers to self-assembled fibers or wormlike micelles. The presence of these different self-assembled structures at high pH is confirmed through NMR and circular dichroism spectroscopy, scanning probe microscopy and cryogenic transmission electron microscopy. PMID:28272523

Production of volatile fatty acids from sewage organic matter by combined bioflocculation and alkaline fermentation.

PubMed

Khiewwijit, Rungnapha; Temmink, Hardy; Labanda, Alvaro; Rijnaarts, Huub; Keesman, Karel J

2015-12-01

This study explored the potential of volatile fatty acids (VFA) production from sewage by a combined high-loaded membrane bioreactor and sequencing batch fermenter. VFA production was optimized with respect to SRT and alkaline pH (pH 8-10). Application of pH shock to a value of 9 at the start of a sequencing batch cycle, followed by a pH uncontrolled phase for 7days, gave the highest VFA yield of 440mgVFA-COD/g VSS. This yield was much higher than at fermentation without pH control or at a constant pH between 8 and 10. The high yield in the pH 9 shocked system could be explained by (1) a reduction of methanogenic activity, or (2) a high degree of solids degradation or (3) an enhanced protein hydrolysis and fermentation. VFA production can be further optimized by fine-tuning pH level and longer operation, possibly allowing enrichment of alkalophilic and alkali-tolerant fermenting microorganisms. Copyright © 2015 Elsevier Ltd. All rights reserved.

High Power, Millimeter-Wavelength, Coherent Radiation Sources.

DTIC Science & Technology

1986-09-25

J . Murphy, Ph.D. (1982). 5. M. Abdelkarim , Ph.D. (1984). 6. T. Buller, Ph.D. (1985). a 7. B. Johnson, Ph.D. (1985). 8. E. Garate, Ph.D. (1985). 9. R...AD-A174 521 HIGH POWER KILL IMETER-WAVELENGTH COHERENTRAITO 1/ SOURCES(U) DARTMOUTH COLL HANOVER N H DEPT OF PHYSICS AND ASTRONOMY J E WALSH 25 SEP...82 - 1/31/86 -.: AIR F , 2 ..... . . T . ... ...... , 7 Approved for public release;"":" " ’n2. j ;’L’-’ ,- -"!d ,-d 12 l . 7. ... - ’ " + d. Chief

Consumer acceptability of low-sugar watermelon sweetened with non-calorie sweetener by a Native American community.

PubMed

Collins, Julie K; Davis, Angela R; Adams, Arin; Manness, Niels; Perkins-Veazie, Penelope M

2006-01-01

Watermelons are a good source of lycopene, a carotenoid that exhibits antioxidant activity and may protect against some cancers. However, intake of watermelon may be restricted for individuals who have diabetes or those who limit carbohydrate intake. A low-sugar watermelon was developed at Lane, Oklahoma using traditional plant breeding techniques. The objective of this study was to determine whether the artificially sweetened low-sugar watermelon was acceptable with Native Americans, a group with a high incidence of diabetes. The red flesh from a low-sugar watermelon and a commercial variety of watermelon was removed and cut into cubes. Low and high levels of artificial sweetener were added to the low-sugar watermelon. Students at a Native American school (Grades 1-12) and adults at a Native American Feeding Center were asked to rate how much they liked or disliked the watermelon using a seven-point hedonic scale. Sugar composition, pH, lycopene and other carotenoids were analyzed from samples using established methods. The pH, lycopene, beta-carotene and total carotenoid levels were similar among fruit. Artificially sweetened fruit were rated slightly more acceptable in taste than the commercial control watermelons by both age groups. The low-sugar watermelons were lower in sugar composition but were comparable with conventional melons in all other quality factors and were found acceptable in taste by a broad age group of Native American consumers.

The initial freezing point temperature of beef rises with the rise in pH: a short communication.

PubMed

Farouk, M M; Kemp, R M; Cartwright, S; North, M

2013-05-01

This study tested the hypothesis that the initial freezing point temperature of meat is affected by pH. Sixty four bovine M. longissimus thoracis et lumborum were classified into two ultimate pH groups: low (<5.8) and high pH (>6.2) and their cooling and freezing point temperatures were determined. The initial freezing temperatures for beef ranged from -0.9 to -1.5°C (∆=0.6°C) with the higher and lower temperatures associated with high and low ultimate pH respectively. There was a significant correlation (r=+0.73, P<0.01) between beef pH and freezing point temperature in the present study. The outcome of this study has implications for the meat industry where evidence of freezing (ice formation) in a shipment as a result of high pH meat could result in a container load of valuable chilled product being downgraded to a lower value frozen product. Copyright © 2013 Elsevier Ltd. All rights reserved.

Functional photoacoustic microscopy of pH

NASA Astrophysics Data System (ADS)

Chatni, M. Rameez; Yao, Junjie; Danielli, Amos; Favazza, Christopher P.; Maslov, Konstantin I.; Wang, Lihong V.

2012-02-01

pH is a tightly regulated indicator of metabolic activity. In mammalian systems, imbalance of pH regulation may result from or result in serious illness. Even though the regulation system of pH is very robust, tissue pH can be altered in many diseases such as cancer, osteoporosis and diabetes mellitus. Traditional high-resolution optical imaging techniques, such as confocal microscopy, routinely image pH in cells and tissues using pH sensitive fluorescent dyes, which change their fluorescence properties with the surrounding pH. Since strong optical scattering in biological tissue blurs images at greater depths, high-resolution pH imaging is limited to penetration depths of 1mm. Here, we report photoacoustic microscopy (PAM) of commercially available pH-sensitive fluorescent dye in tissue phantoms. Using both opticalresolution photoacoustic microscopy (OR-PAM), and acoustic resolution photoacoustic microscopy (AR-PAM), we explored the possibility of recovering the pH values in tissue phantoms. In this paper, we demonstrate that PAM was capable of recovering pH values up to a depth of 2 mm, greater than possible with other forms of optical microscopy.

SUPPORT FOR HU CFRT SUMMER HIGH SCHOOL FUSION WORKSHOP

DOE Office of Scientific and Technical Information (OSTI.GOV)

Punjabi, Alkesh

Nine summer fusion science research workshops for minority and female high school students were conducted at the Hampton University Center for Fusion Research and Training from 1996 to 2005. Each workshop was of the duration of eight weeks. In all 35 high school students were mentored. The students presented 28 contributed papers at the annual meetings of the American Physical Society Division of Plasma Physics. These contributed papers were very well received by the plasma physics and fusion science research community. The students won a number of prestigious local, state, and national honors, awards, prizes, and scholarships. The notable amongmore » these are the two regional finalist positions in the 1999 Siemens-Westinghouse Science and Technology Competitions; 1st Place U.S. Army Award, 2006; 1st Place U.S. Naval Science Award, 2006; Yale Science and Engineering Association Best 11th Grade Project, 2006; Society of Physics Students Book Award, 2006; APS Corporate Minority Scholarship and others. This workshop program conducted by the HU CFRT has been an exemplary success, and served the minority and female students exceptionally fruitfully. The Summer High School Fusion Science Workshop is an immensely successful outreach activity conducted by the HU CFRT. In this workshop, we train, motivate, and provide high quality research experiences to young and talented high school scholars with emphasis on under-represented minorities and female students in fusion science and related areas. The purpose of this workshop is to expose minority and female students to the excitement of research in science at an early stage in their academic lives. It is our hope that this may lead the high school students to pursue higher education and careers in physical sciences, mathematics, and perhaps in fusion science. To our knowledge, this workshop is the first and only one to date, of fusion science for under-represented minorities and female high school students at an HBCU. The faculty researchers in the HU CFRT mentor the students during summers. Mentors spend a considerable amount of time and efforts in training, teaching, guiding and supervising research projects. The HU CFRT has so far conducted nine workshops during the summers of 1996-2000 and 2002-2005. The first workshop was conducted in summer 1996. Students for the workshop are chosen from a national pool of exceptionally talented high school rising seniors/juniors. To our knowledge, most of these students have gone on to prestigious universities such as Duke University, John Hopkins University, CalTech, UCLA, Hampton University, etc. after completing their high school. For instance, Tiffany Fisher, participant of the 1996 summer workshop completed her BS in Mathematics at Hampton University in May 2001. She then went on to Wake Forest University at Winston-Salem, North Carolina to pursue graduate studies. Anshul Haldipur, participant of the 1999 summer workshop, began his undergraduate studies at Duke University in 2000. Christina Nguyen and Ilissa Martinez, participants of the 2000 summer workshop, are pursuing their undergraduate degrees at the UCLA and Florida State University respectively. The organizing committee of the APS DPP annual meeting invited Dr. Punjabi to deliver an invited talk on training the next generation of fusion scientists and engineers at the 2005 APS DPP meeting in Denver, CO. The organizing committee distributed a special flier with the Bulletin to highlight this invited talk and another talk on education as well the expo. This has given wide publicity and recognition to our workshops and Hampton University. Prof. Punjabi's talk: 'LI2 2: Training the next generation of fusion scientists and engineers: summer high school fusion science workshop, Bull. Amer. Phys. Soc. 50, 221 (2005)' was very well-received. He talked about HU education and outreach initiative and the HU CFRT Summer High School Workshop. The audience had a considerable number of questions about our workshops and the High School to PhD Pipeline in fusion science. Professor William Mathews of University of Delaware offered to give the HU Team MHD codes to use, and Professor Birdsall of University of California, Berkeley, plasma theory and simulation group, offered to give the team simple simulation codes to use. We are very happy and proud and very gratified by this, and we thank the US DOE OFES, Dr. Sam Barish and Dr. Michael Crisp for their support and encouragement.« less

Something going on in Milan: a review of the 4th International PhD Student Cancer Conference.

PubMed

Segré, C

2010-01-01

The 4th International PhD Student Cancer Conference was held at the IFOM-IEO-Campus in Milan from 19-21 May 2010 http://www.semm.it/events_researchPast.phpThe Conference covered many topics related to cancer, from basic biology to clinical aspects of the disease. All attendees presented their research, by either giving a talk or presenting a poster. This conference is an opportunity to introduce PhD students to top cancer research institutes across Europe.THE CORE PARTICIPANTING INSTITUTES INCLUDED: European School of Molecular Medicine (SEMM)-IFOM-IEO Campus, MilanBeatson Institute for Cancer Research (BICR), GlasgowCambridge Research Institute (CRI), Cambridge, UKMRC Gray Institute of Radiation Biology (GIROB), OxfordLondon Research Institute (LRI), LondonPaterson Institute for Cancer Research (PICR), ManchesterThe Netherlands Cancer Institute (NKI), Amsterdam'You organizers have crushed all my prejudices towards Italians. Congratulations, I enjoyed the conference immensely!' Even if it might have sounded like rudeness for sure this was supposed to be a genuine compliment (at least, that's how we took it), also considering that it was told by a guy who himself was the fusion of two usually antithetical concepts: fashion style and English nationality.The year 2010 has marked an important event for Italian research in the international scientific panorama: the European School of Molecular Medicine (SEMM) had the honour to host the 4th International PhD Student Cancer Conference, which was held from 19-21 May 2010 at the IFOM-IEO-Campus (http://www.semm.it/events_researchPast.php) in Milan.The conference was attended by more than one hundred students, coming from a selection of cutting edge European institutes devoted to cancer research. The rationale behind it is the promotion of cooperation among young scientists across Europe to debate about science and to exchange ideas and experiences. But that is not all, it is also designed for PhD students to get in touch with other prestigious research centres and to create connections for future post docs or job experiences. And last but not least, it is a golden chance for penniless PhD students to spend a couple of extra days visiting a foreign country (this motivation will of course never be voiced to supervisors).The network of participating institutes has a three-nation core, made up of the Netherlands Cancer Institute, the Italian European School of Molecular Medicine (SEMM) and five UK Cancer Research Institutes (The London Research Institute, The Cambridge Research Institute, The Beatson Institute for Cancer Research in Glasgow, The Patterson Institute for Cancer Research in Manchester and the MRC Gray Institute for Radiation Oncology and Biology in Oxford).The conference is hosted and organised every year by one of the core institutes; the first was in Cambridge in 2007, Amsterdam in 2008 and London in 2009, this year was the turn of Milan.In addition to the core institutes, PhD students from several other high-profile institutes are invited to attend the conference. This year participants applied from the Spanish National Cancer Centre (CNIO, Madrid), the German Cancer Research Centre (DKFZ, Heidelberg), the European Molecular Biology Labs (EMBL, Heidelberg) and the San Raffaele Institute (HSR, Milan). Moreover four 'special guests' from the National Centre for Biological Sciences of Bangalore (India) attended the conference in Milan. This represents a first step in widening the horizons beyond Europe into a global worldwide network of talented PhD students in life sciences.The conference spread over two and a half days (Wednesday 19th to Friday 21st May) and touched on a broad spectrum of topics: from basic biology to development, from cancer therapies to modelling and top-down new generation global approaches. The final selection of presentations has been a tough task for us organisers (Chiara Segré, Federica Castellucci, Francesca Milanesi, Gianluca Varetti and Gian Maria Sarra Ferraris), due to the high scientific level of the abstracts submitted. In the end, 26 top students were chosen to give a 15-min oral presentation in one of eight sessions: Development & Differentiation, Cell Migration, Immunology & Cancer, Modelling & Large Scale approaches, Genome Instability, Signal Transduction, Cancer Genetics & Drug Resistance, Stem Cells in Biology and Cancer.The scientific programme was further enriched by two scientific special sessions, held by Professor Pier Paolo di Fiore and Dr Giuseppe Testa, Principal Investigators at the IFOM-IEO-Campus and by a bioethical round table on human embryonic stem cell research moderated by Silvia Camporesi, a senior PhD student in the SEMM PhD Programme 'Foundation of Life Science and their Bioethical Consequences'.ON TOP OF EVERYTHING, WE HAD THE PLEASURE OF INVITING, AS KEYNOTE SPEAKERS, TWO LEADING EUROPEAN SCIENTISTS IN THE FIELDS OF CANCER INVASION AND BIOLOGY OF STEM CELLS, RESPECTIVELY: Dr Peter Friedl from The Nijmegen Centre for Molecular Life (The Netherlands) and Professor Andreas Trumpp from The Heidelberg Institute for Stem Cell Technology and Experimental Medicine (Heidelberg).All the student talks have distinguished themselves for the impressive quality of the science; an encouraging evidence of the high profile level of research carried out in Europe. It would be beyond the purposes of this report to summarise all 26 talks, which touched many different and specific topics. For further information, the Conference Abstract book with all the scientific content is available on the conference Web site (http://www.semm.it/events_researchPast.php). In what follows, the special sessions and the keynote lectures will be discussed in detail.

Physician Payment Reform—An Idea Whose Time Has Come

PubMed Central

Lee, Philip R.

1990-01-01

These discussions are selected from the weekly staff conferences in the Department of Medicine, University of California, San Francisco. Taken from transcriptions, they are prepared by Homer A. Boushey, MD, Professor of Medicine, and Nathan M. Bass, MD, PhD, Associate Professor of Medicine, under the direction of Lloyd H. Smith, Jr, MD, Professor of Medicine and Associate Dean in the School of Medicine. Requests for reprints should be sent to the Department of Medicine, University of California, San Francisco, School of Medicine, San Francisco, CA 94143. PMID:2185598

Fermentation pH influences the physiological-state dynamics of Lactobacillus bulgaricus CFL1 during pH-controlled culture.

PubMed

Rault, Aline; Bouix, Marielle; Béal, Catherine

2009-07-01

This study aims at better understanding the effects of fermentation pH and harvesting time on Lactobacillus bulgaricus CFL1 cellular state in order to improve knowledge of the dynamics of the physiological state and to better manage starter production. The Cinac system and multiparametric flow cytometry were used to characterize and compare the progress of the physiological events that occurred during pH 6 and pH 5 controlled cultures. Acidification activity, membrane damage, enzymatic activity, cellular depolarization, intracellular pH, and pH gradient were determined and compared during growing conditions. Strong differences in the time course of viability, membrane integrity, and acidification activity were displayed between pH 6 and pH 5 cultures. As a main result, the pH 5 control during fermentation allowed the cells to maintain a more robust physiological state, with high viability and stable acidification activity throughout growth, in opposition to a viability decrease and fluctuation of activity at pH 6. This result was mainly explained by differences in lactate concentration in the culture medium and in pH gradient value. The elevated content of the ionic lactate form at high pH values damaged membrane integrity that led to a viability decrease. In contrast, the high pH gradient observed throughout pH 5 cultures was associated with an increased energetic level that helped the cells maintain their physiological state. Such results may benefit industrial starter producers and fermented-product manufacturers by allowing them to better control the quality of their starters, before freezing or before using them for food fermentation.

The MAYFIELD Project

ERIC Educational Resources Information Center

Mackintosh, Lara

2011-01-01

Dr John Mayfield, PhD (Harvard) was a leader in education as a teacher, inspector, administrator, author and instigator of ideas. He was recognised as being visionary and yet realistically practical. He was involved in the planning and governance of public and private schools and in the design, financing and management of education buildings for…

The Influence of Emerging Leadership in Nursing: An Interview With Dr Casey Shillam.

PubMed

Adams, Jeffrey M

2016-11-01

This department highlights emerging nursing leaders who have demonstrated leadership in advancing innovation and patient care in practice, policy, research, education, and theory. This interview profiles Casey Shillam, PhD, RN, associate dean for baccalaureate education, University of Portland School of Nursing, Oregon.

Serum Antibody Biomarkers for ASD

DTIC Science & Technology

2014-10-01

INVESTIGATOR: Dwight German, Ph.D. CONTRACTING ORGANIZATION: Univ. of Texas Southwestern Medical Center Dallas TX 75390 REPORT DATE: October...2014 TYPE OF REPORT: Annual PREPARED FOR: U.S. Army Medical Research and Materiel Command Fort Detrick...ADDRESS(ES) University of Texas Southwestern Medical School 8. PERFORMING ORGANIZATION REPORT NUMBER Dallas TX 75390 9

Continuing the Conversation: A Response to Apple, Johnston, and Sergiovanni.

ERIC Educational Resources Information Center

Quantz, Richard A.; Cambron-McCabe, Nelda

1991-01-01

Responds to three reviews of "Preparing School Administrators for Democratic Authority" by Richard A. Quantz et al. Discusses issues relating to the Ph.D. program in educational administration at Miami University (Ohio), including relating theory to practice and encouraging graduates to continue to reflect and reconstruct after leaving.…

Alkaliphilic Bacteria with Impact on Industrial Applications, Concepts of Early Life Forms, and Bioenergetics of ATP Synthesis

PubMed Central

Preiss, Laura; Hicks, David B.; Suzuki, Shino; Meier, Thomas; Krulwich, Terry Ann

2015-01-01

Alkaliphilic bacteria typically grow well at pH 9, with the most extremophilic strains growing up to pH values as high as pH 12–13. Interest in extreme alkaliphiles arises because they are sources of useful, stable enzymes, and the cells themselves can be used for biotechnological and other applications at high pH. In addition, alkaline hydrothermal vents represent an early evolutionary niche for alkaliphiles and novel extreme alkaliphiles have also recently been found in alkaline serpentinizing sites. A third focus of interest in alkaliphiles is the challenge raised by the use of proton-coupled ATP synthases for oxidative phosphorylation by non-fermentative alkaliphiles. This creates a problem with respect to tenets of the chemiosmotic model that remains the core model for the bioenergetics of oxidative phosphorylation. Each of these facets of alkaliphilic bacteria will be discussed with a focus on extremely alkaliphilic Bacillus strains. These alkaliphilic bacteria have provided a cogent experimental system to probe adaptations that enable their growth and oxidative phosphorylation at high pH. Adaptations are clearly needed to enable secreted or partially exposed enzymes or protein complexes to function at the high external pH. Also, alkaliphiles must maintain a cytoplasmic pH that is significantly lower than the pH of the outside medium. This protects cytoplasmic components from an external pH that is alkaline enough to impair their stability or function. However, the pH gradient across the cytoplasmic membrane, with its orientation of more acidic inside than outside, is in the reverse of the productive orientation for bioenergetic work. The reversed gradient reduces the trans-membrane proton-motive force available to energize ATP synthesis. Multiple strategies are hypothesized to be involved in enabling alkaliphiles to circumvent the challenge of a low bulk proton-motive force energizing proton-coupled ATP synthesis at high pH. PMID:26090360

Adaptation of the white shrimp Litopenaeus vannamei to gradual changes to a low-pH environment.

PubMed

Han, Si-Yin; Wang, Bao-Jie; Liu, Mei; Wang, Meng-Qiang; Jiang, Ke-Yong; Liu, Xin-Wei; Wang, Lei

2018-03-01

pH variation could cause a stress response in euryhaline penaeids, we evaluated the mortality, growth performance, osmoregulation gene expression, digestive enzyme activity, histology, and resistance against Vibrio parahemolyticus of white shrimp Litopenaeus vannamei reared under conditions of gradual changes to a low-pH environment (gradual-low pH, 6.65-8.20) or a high-pH environment (gradual-high pH, 8.20-9.81) versus a normal pH environment (8.14-8.31) during a 28-d experiment. Consequently, under gradual-high pH, the cumulative mortality rate (CMR) rose with time until 39.9% on days 28; the weight gain percentage (WGP) and length gain percentage (LGP) decreased continuously. However, under gradual-low pH, the CMR of shrimp stabilized at 6.67% during 7-28 d; the WGP and LGP decreased first and then returned to normal. These results indicated that L. vannamei displayed a moderate tolerance to gradual-low pH, compared with gradual-high pH. Under gradual-low pH, the Na + /K + -ATPase, cytoplasmic carbonic anydrase (CAc), and glycosyl-phosphatidylinositol-linked carbonic anhydrase (CAg) transcripts of shrimp increased continuously or then back to normal; the amylase, lipase, and trypsin activities decreased first and then returned to normal or increased; the hepatopancreases and midguts showed histopathological lesions first and then got remission. Thus, the major adaptation mechanism of shrimp to gradual-low pH might be its high osmoregulation ability, which made shrimp achieve a new, balanced steady-state, then promoted longer intestinal villi and recuperative hepatopancreases of shrimp with enhanced digestive enzyme activities to increase nutrient absorption after long-term exposure. Meanwhile, the enhanced resistance against V. parahemolyticus under gradual-low pH would probably inhibit disease outbreak in the shrimp farming. Copyright © 2017 Elsevier Inc. All rights reserved.

Alkaliphilic Bacteria with Impact on Industrial Applications, Concepts of Early Life Forms, and Bioenergetics of ATP Synthesis.

PubMed

Preiss, Laura; Hicks, David B; Suzuki, Shino; Meier, Thomas; Krulwich, Terry Ann

2015-01-01

Alkaliphilic bacteria typically grow well at pH 9, with the most extremophilic strains growing up to pH values as high as pH 12-13. Interest in extreme alkaliphiles arises because they are sources of useful, stable enzymes, and the cells themselves can be used for biotechnological and other applications at high pH. In addition, alkaline hydrothermal vents represent an early evolutionary niche for alkaliphiles and novel extreme alkaliphiles have also recently been found in alkaline serpentinizing sites. A third focus of interest in alkaliphiles is the challenge raised by the use of proton-coupled ATP synthases for oxidative phosphorylation by non-fermentative alkaliphiles. This creates a problem with respect to tenets of the chemiosmotic model that remains the core model for the bioenergetics of oxidative phosphorylation. Each of these facets of alkaliphilic bacteria will be discussed with a focus on extremely alkaliphilic Bacillus strains. These alkaliphilic bacteria have provided a cogent experimental system to probe adaptations that enable their growth and oxidative phosphorylation at high pH. Adaptations are clearly needed to enable secreted or partially exposed enzymes or protein complexes to function at the high external pH. Also, alkaliphiles must maintain a cytoplasmic pH that is significantly lower than the pH of the outside medium. This protects cytoplasmic components from an external pH that is alkaline enough to impair their stability or function. However, the pH gradient across the cytoplasmic membrane, with its orientation of more acidic inside than outside, is in the reverse of the productive orientation for bioenergetic work. The reversed gradient reduces the trans-membrane proton-motive force available to energize ATP synthesis. Multiple strategies are hypothesized to be involved in enabling alkaliphiles to circumvent the challenge of a low bulk proton-motive force energizing proton-coupled ATP synthesis at high pH.

Phenolic contents, antioxidant and anticholinesterase potentials of crude extract, subsequent fractions and crude saponins from Polygonum hydropiper L

PubMed Central

2014-01-01

Background We investigated Polygonum hydropiper L. (P. hydropiper) for phenolic contents, antioxidant, anticholinesterase activities, in an attempt to rationalize its use in neurological disorders. Methods Plant crude extract (Ph.Cr), its subsequent fractions: n-hexane (Ph.Hex), chloroform (Ph.Chf), ethyl acetate (Ph.EtAc), n-Butanol (Ph.Bt), aqueous (Ph.Aq) and saponins (Ph.Sp) were evaluated for 1,1-diphenyl,2-picrylhydrazyl (DPPH), 2,2-azinobis[3-ethylbenzthiazoline]-6-sulfonic acid (ABTS) free radical scavenging potential. Further, acetylcholinesterase (AChE) & butyrylcholinesterase (BChE) inhibitory activities were performed using Ellman's assay. Moreover, total phenolic contents of plant extracts were determined and expressed in mg of gallic acid equivalent per gram of dry sample (mg GAE/g dry weight). Results Among different fractions, Ph.Cr (90.82), Ph.Chf (178.16), Ph.EtAc (203.44) and Ph.Bt (153.61) exhibited high phenolic contents. All fractions showed concentration dependent DPPH scavenging activity, with Ph.EtAc 71.33% (IC50 15 μg/ml), Ph.Bt 71.40% (IC50 3 μg/ml) and Ph.Sp 71.40% (IC50 35 μg/ml) were most potent. The plant extracts exhibited high ABTS scavenging ability i.e. Ph.Bt (91.03%), Ph.EtAc (90.56%), Ph.Sp (90.84%), Ph.Aq (90.56%) with IC50 < 0.01 μg/ml. All fractions showed moderate to high AChE inhibitory activity as; Ph.Cr, 86.87% (IC50 330 μg/ml), Ph.Hex, 87.49% (IC50 35 μg/ml), Ph.Chf, 84.76% (IC50 55 μg/ml), Ph.Sp, 87.58% (IC50 108 μg/ml) and Ph.EtAc 79.95% (IC50 310 μg/ml) at 1 mg/ml). Furthermore the BChE inhibitory activity was most prominent in Ph.Hex 90.30% (IC50 40 μg/ml), Ph.Chf 85.94% (IC50 215 μg/ml), Ph.Aq 87.62% (IC50 3 μg/ml) and Ph.EtAc 81.01% (IC50 395 μg/ml) fractions. Conclusions In this study, for the first time, we determined phenolic contents, isolated crude saponins, investigated antioxidant and anticholinestrase potential of P. hydropiper extracts. The results indicate that P. hydropiper is enriched with potent bioactive compounds and warrant further investigation by isolation and structural elucidation to find novel and affordable compounds for the treatment of various neurological disorders. PMID:24884823

Phenolic contents, antioxidant and anticholinesterase potentials of crude extract, subsequent fractions and crude saponins from Polygonum hydropiper L.

PubMed

Ayaz, Muhammad; Junaid, Muhammad; Ahmed, Jawad; Ullah, Farhat; Sadiq, Abdul; Ahmad, Sajjad; Imran, Muhammad

2014-05-03

We investigated Polygonum hydropiper L. (P. hydropiper) for phenolic contents, antioxidant, anticholinesterase activities, in an attempt to rationalize its use in neurological disorders. Plant crude extract (Ph.Cr), its subsequent fractions: n-hexane (Ph.Hex), chloroform (Ph.Chf), ethyl acetate (Ph.EtAc), n-Butanol (Ph.Bt), aqueous (Ph.Aq) and saponins (Ph.Sp) were evaluated for 1,1-diphenyl,2-picrylhydrazyl (DPPH), 2,2-azinobis[3-ethylbenzthiazoline]-6-sulfonic acid (ABTS) free radical scavenging potential. Further, acetylcholinesterase (AChE) & butyrylcholinesterase (BChE) inhibitory activities were performed using Ellman's assay. Moreover, total phenolic contents of plant extracts were determined and expressed in mg of gallic acid equivalent per gram of dry sample (mg GAE/g dry weight). Among different fractions, Ph.Cr (90.82), Ph.Chf (178.16), Ph.EtAc (203.44) and Ph.Bt (153.61) exhibited high phenolic contents. All fractions showed concentration dependent DPPH scavenging activity, with Ph.EtAc 71.33% (IC50 15 μg/ml), Ph.Bt 71.40% (IC50 3 μg/ml) and Ph.Sp 71.40% (IC50 35 μg/ml) were most potent. The plant extracts exhibited high ABTS scavenging ability i.e. Ph.Bt (91.03%), Ph.EtAc (90.56%), Ph.Sp (90.84%), Ph.Aq (90.56%) with IC50<0.01 μg/ml. All fractions showed moderate to high AChE inhibitory activity as; Ph.Cr, 86.87% (IC50 330 μg/ml), Ph.Hex, 87.49% (IC50 35 μg/ml), Ph.Chf, 84.76% (IC50 55 μg/ml), Ph.Sp, 87.58% (IC50 108 μg/ml) and Ph.EtAc 79.95% (IC50 310 μg/ml) at 1 mg/ml). Furthermore the BChE inhibitory activity was most prominent in Ph.Hex 90.30% (IC50 40 μg/ml), Ph.Chf 85.94% (IC50 215 μg/ml), Ph.Aq 87.62% (IC50 3 μg/ml) and Ph.EtAc 81.01% (IC50 395 μg/ml) fractions. In this study, for the first time, we determined phenolic contents, isolated crude saponins, investigated antioxidant and anticholinestrase potential of P. hydropiper extracts. The results indicate that P. hydropiper is enriched with potent bioactive compounds and warrant further investigation by isolation and structural elucidation to find novel and affordable compounds for the treatment of various neurological disorders.

STS-99 Crew Interviews: Janet L. Kavandi

NASA Technical Reports Server (NTRS)

1999-01-01

This NASA JSC video release is one in a series of space shuttle astronaut interviews and was recorded Aug. 9, 1999. Mission Specialist, Janet L. Kavandi, Ph.D. provides answers to questions regarding her role in the Shuttle Radar Topography Mission (SRTM), mission objectives, which center on the three-dimensional mapping of the entire Earth's surface, shuttle imaging radar, payload mast deploy and retraction, data recording vs. downlinking, the fly cast maneuver, applications of recorded data, international participation (DLR), the National Imaging and Mapping Agency (NIMA), and EarthCam (educational middle school project). The interview is summed up by Dr. Kavandi explaining that the mission's objective, if successful, will result in the the most complete high-resolution digital topographic database of the Earth.

Increased vaginal pH in Ugandan women: what does it indicate?

PubMed

Donders, G G G; Gonzaga, A; Marconi, C; Donders, F; Michiels, T; Eggermont, N; Bellen, G; Lule, J; Byamughisa, J

2016-08-01

Abnormal vaginal flora (AVF), indicative of bacterial vaginosis (BV) and/or aerobic vaginitis (AV), amongst other abnormalities, is a risk factor for multiple complications in pregnant as well as non-pregnant women. Screening for such conditions could help prevent these complications. Can self-testing for increased vaginal pH reliably detect BV and other high-risk microflora types, and is this more accurate than performing Gram stain-based Nugent score when screening for high-risk microflora? A total of 344 women presenting at different outpatient clinics in Mulago Hospital and Mbuikwe Outpatient clinics in Kampala, Uganda, were asked to test themselves by introducing a gloved finger into the vagina and smearing it on a microscopy slide, on which a pH strip was attached. Self-assessed categories of normal (pH 3.6-4.4), intermediate (4.5-4.7) or high pH (>4.7) were compared with demographic and with centralised microscopic data, both in air-dried rehydrated wet mounts (Femicare), as well as in Gram-stained specimens (Nugent). AVF was present in 38 %, BV in 25 % and AV in 11 % of patients. High pH and AVF is correlated with human immunodeficiency virus (HIV), infertility, frequent sex, but not vaginal douching. Screening for raised pH detects 90 % of AVF cases, but would require testing over half of the population. As AV and non-infectious conditions are frequent in women with AVF and high pH, Nugent score alone is an insufficient technique to screen women for a high-risk vaginal microflora, especially in infertile and HIV-infected women.

pH Tolerance in Freshwater Bacterioplankton: Trait Variation of the Community as Measured by Leucine Incorporation

PubMed Central

Kritzberg, Emma

2015-01-01

pH is an important factor determining bacterial community composition in soil and water. We have directly determined the community tolerance (trait variation) to pH in communities from 22 lakes and streams ranging in pH from 4 to 9 using a growth-based method not relying on distinguishing between individual populations. The pH in the water samples was altered to up to 16 pH values, covering in situ pH ± 2.5 U, and the tolerance was assessed by measuring bacterial growth (Leu incorporation) instantaneously after pH adjustment. The resulting unimodal response curves, reflecting community tolerance to pH, were well modeled with a double logistic equation (mean R2 = 0.97). The optimal pH for growth (pHopt) among the bacterial communities was closely correlated with in situ pH, with a slope (0.89 ± 0.099) close to unity. The pH interval, in which growth was ≥90% of that at pHopt, was 1.1 to 3 pH units wide (mean 2.0 pH units). Tolerance response curves of communities originating from circum-neutral pH were symmetrical, whereas in high-pH (8.9) and especially in low-pH (<5.5) waters, asymmetric tolerance curves were found. In low-pH waters, decreasing pH was more detrimental for bacterial growth than increasing pH, with a tendency for the opposite for high-pH waters. A pH tolerance index, using the ratio of growth at only two pH values (pH 4 and 8), was closely related to pHopt (R2 = 0.83), allowing for easy determination of pH tolerance during rapid changes in pH. PMID:26276108

High performance flexible pH sensor based on carboxyl-functionalized and DEP aligned SWNTs

NASA Astrophysics Data System (ADS)

Liu, Lu; Shao, Jinyou; Li, Xiangming; Zhao, Qiang; Nie, Bangbang; Xu, Chuan; Ding, Haitao

2016-11-01

The detection and control of the pH is very important in many biomedical and chemical reaction processes. A miniaturized flexible pH sensor that is light weight, robust, and conformable is very important in many applications, such as multifunctional lab-on-a-chip systems or wearable biomedical devices. In this work, we demonstrate a flexible chemiresistive pH sensor based on dielectrophoresis (DEP) aligned carboxyl-functionalized single-walled carbon nanotubes (SWNTs). Decorated carboxyl groups can react with hydrogen (H+) and hydroxide (OH-) ions, enabling the sensor to be capable of sensing the pH. DEP is used to deposit well-organized and highly aligned SWNTs in desired locations, which improves the metal-nanotube interface and highly rapid detection of the pH, resulting in better overall device performance. When pH buffer solutions are dropped onto such SWNTs, the H+ and OH- ions caninteract with the carboxyl groups and affect the generation of holes and electrons in the SWNTs, leading to resistance variations in the SWNTs. The results shows that the relative resistance variations of the sensor increases linearly with increasing the pH values in the range from 5 to 9 and the response time ranges from 0.2 s to 22.6 s. The pH sensor also shows high performance in mechanical bendability, which benefited from the combination of flexible PET substrates and SWNTs. The SWNT-based flexible pH sensor demonstrates great potential in a wide range of areas due to its simple structure, excellent performance, low power consumption, and compatibility with integrated circuits.

Analyzing the factors that influencing the success of post graduates in achieving graduate on time (GOT) using analytic hierarchy process (AHP)

NASA Astrophysics Data System (ADS)

Chin, Wan Yung; Ch'ng, Chee Keong; Jamil, Jastini Mohd.; Shaharanee, Izwan Nizal Mohd.

2017-11-01

In the globalization era, education plays an important role in educating and preparing individuals to face the demands and challenges of 21st century. Thus, this contributes to the increase of the number of individuals pursuing their studies in Doctor of Philosophy (Ph.D) program. However, the ability of Ph.D students in heading to the four years Graduate on Time (GOT) mission that is stipulated by University has become a major concern of students, institution and government. Therefore, the main objective of this study is to investigate the factors that influence the Ph.D students in Universiti Utara Malaysia (UUM) to achieve GOT. Through the reviewing of previous research, six factors which are student factor, financial factor, supervisor factor, skills factor, project factors and institution factor had been identified as the domain factors that influence the Ph.D students in achieving GOT. The level of importance for each factor will be ranked by the experts from three graduate schools using Analytic Hierarchy Process (AHP) technique. This study will bring a significant contribution to the understanding of factors that affecting the Ph.D students in UUM to achieve GOT. In Addition, this study can also succor the university in planning and assisting the Ph.D students to accomplish the GOT in future.

Strategic innovation between PhD and DNP programs: Collaboration, collegiality, and shared resources.

PubMed

Edwards, Joellen; Rayman, Kathleen; Diffenderfer, Sandra; Stidham, April

2016-01-01

At least 111 schools and colleges of nursing across the nation provide both PhD and DNP programs (AACN, 2014a). Collaboration between nurses with doctoral preparation as researchers (PhD) and practitioners (DNP) has been recommended as essential to further the profession; that collaboration can begin during the educational process. The purpose of this paper is to describe the development and implementation of successful DNP and PhD program collaboration, and to share the results of that collaboration in an educational setting. Faculty set strategic goals to maximize the effectiveness and efficiency of both new DNP and existing PhD programs. The goals were to promote collaboration and complementarity between the programs through careful capstone and dissertation differentiation, complementary residency activities, joint courses and inter-professional experiences; promote collegiality in a blended on-line learning environment through shared orientation and intensive on-campus sessions; and maximize resources in program delivery through a supportive organizational structure, equal access to technology support, and shared faculty responsibilities as appropriate to terminal degrees. Successes such as student and faculty accomplishments, and challenges such as managing class size and workload, are described. Collaboration, collegiality and the sharing of resources have strengthened and enriched both programs and contributed to the success of students, faculty. These innovative program strategies can provide a solid foundation for DNP and PhD collaboration. Copyright © 2016 Elsevier Inc. All rights reserved.

Light-Immune pH Sensor with SiC-Based Electrolyte-Insulator-Semiconductor Structure

NASA Astrophysics Data System (ADS)

Lin, Yi-Ting; Huang, Chien-Shiang; Chow, Lee; Lan, Jyun-Ming; Yang, Chia-Ming; Chang, Liann-Be; Lai, Chao-Sung

2013-12-01

An electrolyte-insulator-semiconductor (EIS) structure with high-band-gap semiconductor of silicon carbide is demonstrated as a pH sensor in this report. Two different sensing membranes, i.e., gadolinium oxide (Gd2O3) and hafnium oxide (HfO2), were investigated. The HfO2 film deposited by atomic layer deposition (ALD) at low temperature shows high pH sensing properties with a sensitivity of 52.35 mV/pH and a low signal of 4.95 mV due to light interference. The EIS structures with silicon carbide can provide better visible light immunity due to its high band gap that allows pH detection in an outdoor environment without degradation of pH sensitivity.

Report on the Third Advanced Chilean School of Astrophysics

NASA Astrophysics Data System (ADS)

Gieren, W.; Zoccali, M.; Saviane, I.; Méndez, R.; Pietrzynski, G.

2007-03-01

During the second week of January 2007, the third Chilean Advanced School of As-trophysics was held at the Universidad de Concepción, the third-largest university in Chile, on “Insights into Galaxy Evolution from Resolved Stellar Populations”. This school, targeted at Ph.D. students main- ly from Chile and South America, but also open to students from other countries, was organised in the framework of the Chilean FONDAP Center of Astrophysics which includes astronomers of the two largest universities in Santiago and the Universidad de Concepción. The school focused on a field of research which is very well represented in the Center. Addi-tional support was kindly offered by the ALMA Committee, ESO Chile, the Católi-ca and Concepción universities, and the Sociedad Chilena de Astronomía.

Children's understandings and motivations surrounding novelty sweets: a qualitative study.

PubMed

Stewart, Kate F; Fairchild, Ruth M; Jones, Rhiannon J; Hunter, Lindsay; Harris, Carole; Morgan, Maria Z

2013-11-01

Novelty sweets resemble or can be used as toys, are brightly coloured, with striking imagery, and sold at pocket money prices. They encourage regular consumption as packaging can be resealed, leading to prolonged exposure of these high-sugar and low pH products to the oral tissues, risk factors for dental caries and erosion, respectively. To determine how children conceptualise novelty sweets and their motivations for buying and consuming them. Focus groups conducted using a brief schedule of open-ended questions, supported by novelty sweets used as prompts in the latter stages. Participants were school children (aged 9-10) from purposively selected state primary schools in Cardiff, UK. Key findings related to the routine nature of sweet eating; familiarity with and availability of novelty sweets; parental awareness and control; lack of awareness of health consequences; and the overall appeal of novelty sweets. Parents reported vagueness regarding consumption habits and permissiveness about any limits they set may have diluted the concept of treats. Flexible permissiveness to sweet buying applied to sweets of all kinds. Parents' reported lack of familiarity with novelty sweets combined with their low cost, easy availability, high sugar content, and acidity give cause for concern. © 2012 John Wiley & Sons Ltd, BSPD and IAPD.

Shumard Oaks Successfully Planted on High pH Soils

Treesearch

Harvey E. Kennedy; Roger M. Krinard

1985-01-01

Shumard oak was successfully planted on high pH (7.8-8.0) Mississippi River alluvium soils where some other planted red oaks had failed. Survival and growth have been good through ages 10, 11, and 25 years in three separate plantings. Shumard oak on high pH soils, in addition to producing timber, would allow a consistent mast-producing tree on sites normally void of...

AWG Scholarships

NASA Astrophysics Data System (ADS)

The Association for Women Geoscientists will give two Chrysalis Scholarships in 1990. The awards are for women who returned to school after an interruption in education of at least a year and who are finishing a thesis for a Masters or Ph.D. degree in geoscience.1989 was the first year for the Chrysalis. The recipient, Diane Bellis, was a doctoral candidate in geochemistry at New Mexico Institute of Mining and Technology in Socorro and the mother of four. She received her Ph.D. in May and is currently an AAAS Fellow in the Department of State in Washington, D.C., working on U.S. science policy in Africa and Latin America.

Diurnal variation in ruminal pH on the digestibility of highly digestible perennial ryegrass during continuous culture fermentation.

PubMed

Wales, W J; Kolver, E S; Thorne, P L; Egan, A R

2004-06-01

Dairy cows grazing high-digestibility pastures exhibit pronounced diurnal variation in ruminal pH, with pH being below values considered optimal for digestion. Using a dual-flow continuous culture system, the hypothesis that minimizing diurnal variation in pH would improve digestion of pasture when pH was low, but not at a higher pH, was tested. Four treatments were imposed, with pH either allowed to exhibit normal diurnal variation around an average pH of 6.1 or 5.6, or maintained at constant pH. Digesta samples were collected during the last 3 d of each of four, 9-d experimental periods. A constant pH at 5.6 compared with a constant pH of 6.1 reduced the digestibility of organic matter (OM), neutral detergent (NDF), and acid detergent fiber (ADF) by 7, 14, and 21%, respectively. When pH was allowed to vary (averaging 5.6), digestion of OM, NDF, and ADF were reduced by 15,30, and 36%, respectively, compared with pH varying at 6.1. There was little difference in digestion parameters when pH was either constant or varied with an average pH of 6.1. However, when average pH was 5.6, maintaining a constant pH significantly increased digestion of OM, NDF, and ADF by 5, 25, and 24% compared with a pH that exhibited normal diurnal variation. These in vitro results show that gains in digestibility and potential milk production can be made by minimizing diurnal variation in ruminal pH, but only when ruminal pH is low (5.6). However, larger gains in productivity can be achieved by increasing average daily ruminal pH from 5.6 to 6.1.

Engineering a highly active thermophilic β-glucosidase to enhance its pH stability and saccharification performance.

PubMed

Xia, Wei; Xu, Xinxin; Qian, Lichun; Shi, Pengjun; Bai, Yingguo; Luo, Huiying; Ma, Rui; Yao, Bin

2016-01-01

β-Glucosidase is an important member of the biomass-degrading enzyme system, and plays vital roles in enzymatic saccharification for biofuels production. Candidates with high activity and great stability over high temperature and varied pHs are always preferred in industrial practice. To achieve cost-effective biomass conversion, exploring natural enzymes, developing high level expression systems and engineering superior mutants are effective approaches commonly used. A newly identified β-glucosidase of GH3, Bgl3A, from Talaromyces leycettanus JCM12802, was overexpressed in yeast strain Pichia pastoris GS115, yielding a crude enzyme activity of 6000 U/ml in a 3 L fermentation tank. The purified enzyme exhibited outstanding enzymatic properties, including favorable temperature and pH optima (75 °C and pH 4.5), good thermostability (maintaining stable at 60 °C), and high catalytic performance (with a specific activity and catalytic efficiency of 905 U/mg and 9096/s/mM on pNPG, respectively). However, the narrow stability of Bgl3A at pH 4.0-5.0 would limit its industrial applications. Further site-directed mutagenesis indicated the role of excessive O-glycosylation in pH liability. By removing the potential O-glycosylation sites, two mutants showed improved pH stability over a broader pH range (3.0-10.0). Besides, with better stability under pH 5.0 and 50 °C compared with wild type Bgl3A, saccharification efficiency of mutant M1 was improved substantially cooperating with cellulase Celluclast 1.5L. And mutant M1 reached approximately equivalent saccharification performance to commercial β-glucosidase Novozyme 188 with identical β-glucosidase activity, suggesting its great prospect in biofuels production. In this study, we overexpressed a novel β-glucosidase Bgl3A with high specific activity and high catalytic efficiency in P. pastoris. We further proved the negative effect of excessive O-glycosylation on the pH stability of Bgl3A, and enhanced the pH stability by reducing the O-glycosylation. And the enhanced mutants showed much better application prospect with substantially improved saccharification efficiency on cellulosic materials.

Fe{sub 2}O{sub 3}-Bi{sub 2}O{sub 3}-B{sub 2}O{sub 3} glasses as lithium-free nonsilicate pH responsive glasses – Compatibility between pH responsivity and hydrophobicity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hashimoto, Tadanori, E-mail: hasimoto@chem.mie-u.ac.jp; Hamajima, Mitsuaki; Ohta, Honami

Highlights: • Fe{sub 2}O{sub 3}-rich FeBiB glasses show high pH sensitivity and short pH response time. • Bi{sub 2}O{sub 3}-rich FeBiB glasses show relatively high contact angle for water. • FeBiB glasses are lithium-free nonsilicate pH responsive ones. • pH responsivity and hydrophobicity are obtained for optimum glass compositions. - Abstract: Lithium silicate-based glasses have widely been used as commercially available pH glass electrodes. It was revealed that Ti{sup 3+}-containing titanophosphate (TiO{sub 2}-P{sub 2}O{sub 5}, TP) glasses are pH responsive as lithium-free nonsilicate glasses for the first time. TP glasses with the compatibility between pH responsivity and self-cleaning property weremore » obtained by the sequential post-annealing (oxidation and reduction) of as-prepared glasses. Bi{sub 2}O{sub 3}-B{sub 2}O{sub 3} (BiB) glasses are relatively hydrophobic and are expected to show anti-fouling effect. They are unsuitable for pH responsive glasses, because they have high electrical resistivity. In the present study, xFe{sub 2}O{sub 3}·yBi{sub 2}O{sub 3}·(100 − x − y)B{sub 2}O{sub 3} glasses (xFeyBiB, x = 0–20 mol%, y = 20–80 mol%) glasses were selected as new pH responsive glasses with hydrophobicity, because Fe{sub 2}O{sub 3} is a representative component for causing hopping conduction to the glasses. BiB glass did not show pH responsivity, whereas xFeyBiB glasses showed good pH responsivity. xFeyBiB glasses are lithium-free nonsilicate pH responsive ones as well as TP glasses. The electrical resistivity and pH response time decreased with increasing Fe{sub 2}O{sub 3} content. The pH repeatability for standard solutions increased with increasing Bi{sub 2}O{sub 3} content. Silicate glass (20Fe70BiSi) showed better pH responsivity but lower contact angle than those of borate glass (20Fe70BiB). pH sensitivity increased in order of TP glasses (about 80%), xFeyBiB glasses (about 90%) and commercial pH responsive glass (about 100%). xFeyBiB glasses showed short pH response time compared to commercial pH responsive glass. The contact angle for water of xFeyBiB glasses was relatively high (about 90°) as well as BiB glasses, and increased slightly with increasing Bi{sub 2}O{sub 3} content regardless Fe{sub 2}O{sub 3} content. The high contact angle was related to low OH content determined by FT-IR measurement. Thus, 20Fe{sub 2}O{sub 3}·70Bi{sub 2}O{sub 3}·10B{sub 2}O{sub 3} glass was the most suitable one as pH responsive glasses with hydrophobicity. TP glasses are pH responsive ones with self-cleaning property, whereas xFeyBiB glasses are expected as pH responsive ones with anti-fouling property based on hydrophobicity.« less

Highly Sensitive and Wide-Dynamic-Range Multichannel Optical-Fiber pH Sensor Based on PWM Technique.

PubMed

Khan, Md Rajibur Rahaman; Kang, Shin-Won

2016-11-09

In this study, we propose a highly sensitive multichannel pH sensor that is based on an optical-fiber pulse width modulation (PWM) technique. According to the optical-fiber PWM method, the received sensing signal's pulse width changes when the optical-fiber pH sensing-element of the array comes into contact with pH buffer solutions. The proposed optical-fiber PWM pH-sensing system offers a linear sensing response over a wide range of pH values from 2 to 12, with a high pH-sensing ability. The sensitivity of the proposed pH sensor is 0.46 µs/pH, and the correlation coefficient R² is approximately 0.997. Additional advantages of the proposed optical-fiber PWM pH sensor include a short/fast response-time of about 8 s, good reproducibility properties with a relative standard deviation (RSD) of about 0.019, easy fabrication, low cost, small size, reusability of the optical-fiber sensing-element, and the capability of remote sensing. Finally, the performance of the proposed PWM pH sensor was compared with that of potentiometric, optical-fiber modal interferometer, and optical-fiber Fabry-Perot interferometer pH sensors with respect to dynamic range width, linearity as well as response and recovery times. We observed that the proposed sensing systems have better sensing abilities than the above-mentioned pH sensors.

Highly Sensitive and Wide-Dynamic-Range Multichannel Optical-Fiber pH Sensor Based on PWM Technique

PubMed Central

Khan, Md. Rajibur Rahaman; Kang, Shin-Won

2016-01-01

In this study, we propose a highly sensitive multichannel pH sensor that is based on an optical-fiber pulse width modulation (PWM) technique. According to the optical-fiber PWM method, the received sensing signal’s pulse width changes when the optical-fiber pH sensing-element of the array comes into contact with pH buffer solutions. The proposed optical-fiber PWM pH-sensing system offers a linear sensing response over a wide range of pH values from 2 to 12, with a high pH-sensing ability. The sensitivity of the proposed pH sensor is 0.46 µs/pH, and the correlation coefficient R2 is approximately 0.997. Additional advantages of the proposed optical-fiber PWM pH sensor include a short/fast response-time of about 8 s, good reproducibility properties with a relative standard deviation (RSD) of about 0.019, easy fabrication, low cost, small size, reusability of the optical-fiber sensing-element, and the capability of remote sensing. Finally, the performance of the proposed PWM pH sensor was compared with that of potentiometric, optical-fiber modal interferometer, and optical-fiber Fabry–Perot interferometer pH sensors with respect to dynamic range width, linearity as well as response and recovery times. We observed that the proposed sensing systems have better sensing abilities than the above-mentioned pH sensors. PMID:27834865

An alkaline active xylanase: insights into mechanisms of high pH catalytic adaptation.

PubMed

Mamo, Gashaw; Thunnissen, Marjolein; Hatti-Kaul, Rajni; Mattiasson, Bo

2009-09-01

The alkaliphilic bacterium, Bacillus halodurans S7, produces an alkaline active xylanase (EC 3.2.1.8), which differs from many other xylanases in being operationally stable under alkaline conditions as well as at elevated temperature. Compared to non-alkaline active xylanases, this enzyme has a high percent composition of acidic amino acids which results in high ratio of negatively to positively charged residues. A positive correlation was observed between the charge ratio and the pH optima of xylanases. The recombinant xylanase was crystallized using a hanging drop diffusion method. The crystals belong to the space group P2(1)2(1)2(1) and the structure was determined at a resolution of 2.1 A. The enzyme has the common eight-fold TIM-barrel structure of family 10 xylanases; however, unlike non-alkaline active xylanases, it has a highly negatively charged surface and a deeper active site cleft. Mutational analysis of non-conserved amino acids which are close to the acid/base residue has shown that Val169, Ile170 and Asp171 are important to hydrolyze xylan at high pH. Unlike the wild type xylanase which has optimum pH at 9-9.5, the triple mutant xylanase (V169A, I170F and D171N), which was constructed using sequence information of alkaline sensitive xylanses was optimally active around pH 7. Compared to non-alkaline active xylanases, the alkaline active xylanases have highly acidic surfaces and fewer solvent exposed alkali labile residues. Based on these results obtained from sequence, structural and mutational analysis, the possible mechanisms of high pH stability and catalysis are discussed. This will provide useful information to understand the mechanism of high pH adaptation and engineering of enzymes that can be operationally stable at high pH.

The training, careers, and work of Ph.D. physical scientists: Not simply academic

NASA Astrophysics Data System (ADS)

Smith, Steven J.; Pedersen-Gallegos, Liane; Riegle-Crumb, Catherine

2002-11-01

We present an in-depth portrait of the training, careers, and work of recent Ph.D. physical scientists. Use of specialized training varies widely, with about half often using knowledge of their Ph.D. specialty area in their jobs. The use of specialized training does not, however, correlate with job satisfaction. In this and other important measures, there are relatively few differences between "academics" and "nonacademics." Important job skills for all employment sectors include writing, oral presentation, management, data analysis, designing projects, critical thinking, and working in an interdisciplinary context. Rankings given by respondents of graduate training in some of these skill areas were significantly lower than the importance of these skills in the workplace. We also found that the rated quality of graduate training varies relatively little by department or advisor. Finally, although nonacademic aspirations among graduate students are fairly common, these do not appear to be well supported while in graduate school.

Lessons Learned from 25 Years of Health Communication Research to Eliminate Health Disparities

Cancer.gov

Matthew Kreuter is the Kahn Family Professor and Associate Dean for Public Health at the Brown School of Washington University in St. Louis.  He is founder of the Health Communication Research Laboratory (HCRL), a leading center nationally that is now in its 22nd year of continuous funding. Dr. Kreuter’s research seeks to identify and apply communication-based strategies to eliminate health disparities.  In particular, his work focused on finding ways to increase the reach and effectiveness of health information to low-income and minority populations, and using information and technology to connect them to needed health services. Kreuter served for six years on the Institute of Medicine’s Board on Population Health and Public Health Practice, and in 2014 was named by Thompson Reuters as one of the most influential scientists in the world, ranking in the top 1 percent in his field based on the number of highly cited papers. He received his PhD and MPH in Health Behavior and Health Education from the School of Public Health at the University of North Carolina – Chapel Hill.  

Physics and Novel Schemes of Laser Radiation Pressure Acceleration for Quasi-monoenergetic Proton Generation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Chuan S.; Shao, Xi

2016-06-14

The main objective of our work is to provide theoretical basis and modeling support for the design and experimental setup of compact laser proton accelerator to produce high quality proton beams tunable with energy from 50 to 250 MeV using short pulse sub-petawatt laser. We performed theoretical and computational studies of energy scaling and Raleigh--Taylor instability development in laser radiation pressure acceleration (RPA) and developed novel RPA-based schemes to remedy/suppress instabilities for high-quality quasimonoenergetic proton beam generation as we proposed. During the project period, we published nine peer-reviewed journal papers and made twenty conference presentations including six invited talks onmore » our work. The project supported one graduate student who received his PhD degree in physics in 2013 and supported two post-doctoral associates. We also mentored three high school students and one undergraduate student of physics major by inspiring their interests and having them involved in the project.« less

Influence of extraction pH on the foaming, emulsification, oil-binding and visco-elastic properties of marama protein.

PubMed

Gulzar, Muhammad; Taylor, John Rn; Minnaar, Amanda

2017-11-01

Marama bean protein, as extracted previously at pH 8, forms a viscous, adhesive and extensible dough. To obtain a protein isolate with optimum functional properties, protein extraction under slightly acidic conditions (pH 6) was investigated. Two-dimensional electrophoresis showed that pH 6 extracted marama protein lacked some basic 11S legumin polypeptides, present in pH 8 extracted protein. However, it additionally contained acidic high molecular weight polypeptides (∼180 kDa), which were disulfide crosslinked into larger proteins. pH 6 extracted marama proteins had similar emulsification properties to soy protein isolate and several times higher foaming capacity than pH 8 extracted protein, egg white and soy protein isolate. pH 6 extracted protein dough was more elastic than pH 8 extracted protein, approaching the elasticity of wheat gluten. Marama protein extracted at pH 6 has excellent food-type functional properties, probably because it lacks some 11S polypeptides but has additional high molecular weight proteins. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

Mode of de-esterification of alkaline and acidic pectin methyl esterases at different pH conditions.

PubMed

Duvetter, Thomas; Fraeye, Ilse; Sila, Daniel N; Verlent, Isabel; Smout, Chantal; Hendrickx, Marc; Van Loey, Ann

2006-10-04

Highly esterified citrus pectin was de-esterified at pH 4.5 and 8.0 by a fungal pectin methyl esterase (PME) that was shown to have an acidic isoelectric pH (pI) and an acidic pH optimum and by a plant PME that was characterized by an alkaline pI and an alkaline pH optimum. Interchain and intrachain de-esterification patterns were studied by digestion of the pectin products with endo-polygalacturonase and subsequent analysis using size exclusion and anion-exchange chromatography. No effect of pH was observed on the de-esterification mode of either of the two enzymes. Acidic, fungal PME converted pectin according to a multiple-chain mechanism, with a limited degree of multiple attack at the intrachain level, both at pH 4.5 and at pH 8.0. A multiple-attack mechanism, with a high degree of multiple attack, was more appropriate to describe the action mode of alkaline, plant PME, both at pH 4.5 and at pH 8.0.

Oxidation of bisphenol F (BPF) by manganese dioxide.

PubMed

Lu, Zhijiang; Lin, Kunde; Gan, Jay

2011-10-01

Bisphenol F (BPF), an environmental estrogen, is used as a monomer in plastic industry and its environmental fate and decontamination are emerging concern. This study focused on the kinetics, influencing factors and pathways of its oxidation by MnO(2). At pH 5.5, about 90% of BPF was oxidized in 20 min in a solution containing 100 μM MnO(2) and 4.4 μM BPF. The reaction was pH-dependent, following an order of pH 4.5 > pH 5.5 > pH 8.6 > pH 7.5 > pH 6.5 > pH 9.6. Humic acids inhibited the reaction at low (≤ pH 5.5) and high pH (≥ pH 8.6) at high concentrations. In addition, metal ions and anions also suppressed the reaction, following the order Mn(2+) > Ca(2+) > Mg(2+) > Na(+) and HPO(4)(2-) > Cl(-) > NO(3)(-) ≈ SO(4)(2-), respectively. A total of 5 products were identified, from which a tentative pathway was proposed. Copyright © 2011 Elsevier Ltd. All rights reserved.

The influence of normal and high ultimate muscle pH on the microbiology and colour stability of previously frozen black wildebeest (Connochaetes gnou) meat.

PubMed

Shange, Nompumelelo; Makasi, Thandeka N; Gouws, Pieter A; Hoffman, Louwrens C

2018-01-01

Changes in pH, colour and microbiological counts were investigated in previously frozen Biceps femoris (BF) muscles from black wildebeest. Samples were stored under vacuum at refrigerated conditions (4.2±0.8°C) for 12days. Seven BF muscles had a high pH (DFD) (pH≥6) and five had a normal pH (pH<6). Overtime the pH of DFD did not significantly change whilst that of normal pH meat decreased. Browning under anaerobic storage conditions was seen, more for normal meat than DFD meat. Initial total viable counts, lactic acid bacteria and coliform counts from samples with normal pH, were significantly higher than counts from the DFD samples. However, overtime DFD meat showed a faster increase for all microorganisms tested compared to normal pH meat. Overall, this study revealed that DFD meat can have a shorter shelf-life than normal pH meat stored at 4.2±0.8°C. Copyright © 2017 Elsevier Ltd. All rights reserved.

Knowledge base and functionality of concepts of some Filipino biology teachers in five biology topics

NASA Astrophysics Data System (ADS)

Barquilla, Manuel B.

2018-01-01

This mixed research, is a snapshot of some Filipino Biology teachers' knowledge structure and how their concepts of the five topics in Biology (Photosynthesis, Cellular Respiration, human reproductive system, Mendelian genetics and NonMendelian genetics) functions and develops inside a biology classroom. The study focuses on the six biology teachers and a total of 222 students in their respective classes. Of the Six (6) teachers, three (3) are under the Science curriculum and the other three (3) are under regular curriculum in both public and private schools in Iligan city and Lanao del Norte, Philippines. The study utilized classroom discourses, concept maps, interpretative case-study method, bracketing method, and concept analysis for qualitative part; the quantitative part uses a nonparametric statistical tool, Kendall's tau Coefficient for determining relationship and congruency while measures of central tendencies and dispersion (mean, and standard deviation) for concept maps scores interpretation. Knowledge Base of Biology teachers were evaluated by experts in field of specialization having a doctorate program (e.g. PhD in Genetics) and PhD Biology candidates. The data collection entailed seven (7) months immersion: one (1) month for preliminary phase for the researcher to gain teachers' and students' confidence and the succeeding six (6) months for main observation and data collection. The evaluation of teachers' knowledge base by experts indicated that teachers' knowledge of (65%) is lower than the minimum (75%) recommended by ABD-el-Khalick and Boujaoude (1997). Thus, the experts believe that content knowledge of the teachers is hardly adequate for their teaching assignment. Moreover, the teachers in this study do not systematically use reallife situation to apply the concepts they teach. They can identify concepts too abstract for their student; however, they seldom use innovative ways to bring the discussion to their students' level of readiness and capacity to learn. Kendall's Tau Coefficient of agreement indicated that there is an agreement of the rating by experts and PhD (Biology) candidates. As for recommended level for teaching based on the respondent content knowledge structure, the experts and the PhD (Biology) candidates agree that the content knowledge of the teachers is at the borderline (rating of 6) between elementary and high school. These results imply that biology teachers need in-service training to upgrade their content knowledge in the subject. At the same time, the pre-service curriculum for biology teachers needs upgrading.

Active-learning versus teacher-centered instruction for learning acids and bases

NASA Astrophysics Data System (ADS)

Acar Sesen, Burcin; Tarhan, Leman

2011-07-01

Background and purpose: Active-learning as a student-centered learning process has begun to take more interest in constructing scientific knowledge. For this reason, this study aimed to investigate the effectiveness of active-learning implementation on high-school students' understanding of 'acids and bases'. Sample The sample of this study was 45 high-school students (average age 17 years) from two different classes, which were randomly assigned to the experimental (n = 21) and control groups (n = 25), in a high school in Turkey. Design and methods A pre-test consisting of 25 items was applied to both experimental and control groups before the treatment in order to identify student prerequisite knowledge about their proficiency for learning 'acids and bases'. A one-way analysis of variance (ANOVA) was conducted to compare the pre-test scores for groups and no significant difference was found between experimental (ME = 40.14) and control groups (MC = 41.92) in terms of mean scores (F 1,43 = 2.66, p > 0.05). The experimental group was taught using an active-learning curriculum developed by the authors and the control group was taught using traditional course content based on teacher-centered instruction. After the implementation, 'Acids and Bases Achievement Test' scores were collected for both groups. Results ANOVA results showed that students' 'Acids and Bases Achievement Test' post-test scores differed significantly in terms of groups (F 1,43 = 102.53; p < 0.05). Additionally, in this study 54 misconceptions, 14 of them not reported in the literature before, were observed in the following terms: 'acid and base theories'; 'metal and non-metal oxides'; 'acid and base strengths'; 'neutralization'; 'pH and pOH'; 'hydrolysis'; 'acid-base equilibrium'; 'buffers'; 'indicators'; and 'titration'. Based on the achievement test and individual interview results, it was found that high-school students in the experimental group had fewer misconceptions and understood the concepts more meaningfully than students in control group. Conclusion The study revealed that active-learning implementation is more effective at improving students' learning achievement and preventing misconceptions.

The Teach for America RockCorps, Year 2: Using Authentic Research Experiences in Geophysics for STEM Teachers to Inspire Earth Science-Themed Lessons in High School Classrooms

NASA Astrophysics Data System (ADS)

Parsons, B.; Kassimu, R.; Borjas, C. N.; Griffith, W. A.

2016-12-01

Brooke Parsons1, Rahmatu Kassimu2, Christopher Borjas3, and W. Ashley Griffith31Uplift Hampton Preparatory High School, Dallas, TX, 75232 2H. Grady Spruce High School, Dallas, TX, 75217 3Department of Earth and Environmental Sciences, University of Texas Arlington, Arlington, TX, 76019 As Earth Science courses appear in fewer high school curricula, we seek to find creative ways to integrate Earth Science themes as contextual examples into other K-12 STEM courses in order to develop (A) Earth Science literacy, and (B) a pipeline of young talent into our field. This presentation details the efforts of the 2nd year Teach for America (TFA) Rock Corps, a five year NSF-sponsored partnership between TFA and the University of Texas at Arlington designed to provide STEM teachers with genuine research opportunities using components that can be extrapolated to develop dynamic Geophysics-themed lesson plans and materials for their classrooms. Two teachers were selected from the Dallas-Fort Worth region of TFA to participate in original research modeling off-fault damage that occurs during earthquakes in a lab setting using a Split-Hopkinson-Pressure Bar (SHPB). In particular, we simulate a coseismic transient stress perturbation in a fault damage zone by combining traditional SHPB with a traveling harmonic oscillator: Two striker bars attached by an elastic spring are launched with a gas gun allowing us to create the double stress pulse expected during an earthquake rupture. This research affords teachers inspiration to implement Geophysics-themed lesson plans for their courses, Physics/Pre-AP Physics and Chemistry. The physics course will adopt principles of seismic wave propagation to teach concepts of impulse, momentum, conservation of energy, harmonic motion, wave velocity, wave propagation, and real world applications of waves. The chemistry course will implement geochemistry themed techniques into applying the scientific method, density, isotopic composition, pH calculations, and conservation of mass/energy. These course adaptations will address different learning objectives specified by the Texas Essential Knowledge and Skills (TEKS), and provide students with concrete labs, examples, and demonstrations of concepts through a geoscience lens.

Effect of repeated injection and continuous infusion of omeprazole and ranitidine on intragastric pH over 72 hours.

PubMed

Netzer, P; Gaia, C; Sandoz, M; Huluk, T; Gut, A; Halter, F; Hüsler, J; Inauen, W

1999-02-01

In healthy subjects and patients with bleeding peptic ulcers, ranitidine and omeprazole, given parenterally, achieve high intragastric pH values on the first day of therapy. However, data on the antisecretory effect beyond the first 24 h is scanty. In addition, the superiority of either infusion or injection of omeprazole remains unproven. Thus, we have compared the antisecretory effect of high dose omeprazole and ranitidine infusion and injection over the critical first 72 h. A total of 34 healthy volunteers were randomized into a double-blind crossover 72 h intragastric pH-metry study (data compared: median pH, percentage of time with pH >4 and pH >6). Omeprazole-infusion: initial bolus of 80 mg + 8 mg/h; omeprazole-injection: initial bolus of 80 mg + 40 mg/6 h; Ranitidine-infusion: initial bolus of 50 mg + 0.25 mg/kg/h; ranitidine-injection: 100 mg/6 h. Omeprazole-infusion versus ranitidine-infusion: on day 1: median pH 6.1 vs 5.1 (p = 0.01) and 95% vs 70% was pH >4 (p < 0.01); on day 2: median pH 6.2 vs 3.2 (p < 0.01); and 100% vs 38% was pH >4 (p < 0.01); on day 3: median pH 6.3 vs 2.7 (p < 0.01); 100% vs 26% was pH >4 (p < 0.01). Injections of both drugs were significantly less effective than the infusions on day 1. Thereafter, omeprazole injection was almost as effective as omeprazole infusion, whereas ranitidine injection and infusion were equally effective. Our study shows, for the first time, that omeprazole infusion was significantly superior to all other regimens by having a high median pH >6 on each day. The tolerance effect of ranitidine, however, led to a rapid loss of antisecretory activity on days 2 and 3, rendering it inappropriate for situations in which high intragastric pH-levels appear to be essential.

Surface laser alloying of 17-4PH stainless steel steam turbine blades

NASA Astrophysics Data System (ADS)

Yao, Jianhua; Wang, Liang; Zhang, Qunli; Kong, Fanzhi; Lou, Chenghua; Chen, Zhijun

2008-09-01

As a known high-quality precipitation hardening stainless steel with high strength, high antifatigue, excellent corrosion resistance and good weldability, 17-4PH has been widely used to produce steam turbine blades. However, under the impact of high-speed steam and water droplets, the blades are prone to cavitation, which could lead to lower efficiency, shorter life time, and even accidents. In this article, the 17-4PH blade's surface was alloyed using a high power CO 2 laser. The microstructure and microhardness of hardened 17-4PH were tested by scanning electronic microscope (SEM), X-ray diffraction (XRD), energy disperse spectroscopy (EDS) and a microhardness tester. After laser alloying, the surface layer was denser and the grain refined, while the microhardness of the surface (average 610HV 0.2) was about one times higher than that of the substrate material (330HV 0.2). The friction coefficient of the laser-alloyed 17-4PH layer was much lower than that of the substrate.

Publication Rates of Social and Administrative Sciences Pharmacy Faculty in Non-Research Intensive Pharmacy Schools.

PubMed

Weathers, Trenna; Unni, Elizabeth

2018-04-01

Objective. To assess the level of publication rates from 2011 through 2015 by Social and Administrative Sciences (SAS) faculty at non-research intensive pharmacy schools. Methods. The Web of Science database was searched using faculty names identified from the American Association of Colleges of Pharmacy (AACP) faculty and professional staff roster. Publication rates of SAS faculty were calculated and compared using several demographic subcategories such as public/private school, part of an academic health center, schools with PhD program, funding status, etc. Results. The 208 SAS faculty members from 59 colleges contributed to 478 publications with a mean of 95.6 publications per year and 1.62 publications per institution per year. The number of publications increased 45% over the five years from 67 publications in 2011 to 122 in 2015.The average number of publications was 0.92 per year per SAS faculty compared to 0.82 publications per year per faculty from other basic pharmaceutical sciences divisions. The most commonly published research was research articles in the area of scholarship of teaching and learning. The significant predictors of publications were being part of an academic health center, having a PhD program, and higher percent of faculty members who are SAS faculty. Conclusion. Despite being affiliated with institutions with missions less targeted on research, this study showed SAS faculty members at non-research intensive institutions consistently contribute to published literature. Further studies are needed to examine reasons for the lack of publishing by almost half of the SAS faculty and ways to increase research and publication in the field of SAS.

Self-reported needs for improving the supervision competence of PhD supervisors from the medical sciences in Denmark.

PubMed

Raffing, Rie; Jensen, Thor Bern; Tønnesen, Hanne

2017-10-23

Quality of supervision is a major predictor for successful PhD projects. A survey showed that almost all PhD students in the Health Sciences in Denmark indicated that good supervision was important for the completion of their PhD study. Interestingly, approximately half of the students who withdrew from their program had experienced insufficient supervision. This led the Research Education Committee at the University of Copenhagen to recommend that supervisors further develop their supervision competence. The aim of this study was to explore PhD supervisors' self-reported needs and wishes regarding the content of a new program in supervision, with a special focus on the supervision of PhD students in medical fields. A semi-structured interview guide was developed, and 20 PhD supervisors from the Graduate School of Health and Medical Sciences at the Faculty of Health and Medical Sciences at the University of Copenhagen were interviewed. Empirical data were analysed using qualitative methods of analysis. Overall, the results indicated a general interest in improved competence and development of a new supervision programme. Those who were not interested argued that, due to their extensive experience with supervision, they had no need to participate in such a programme. The analysis revealed seven overall themes to be included in the course. The clinical context offers PhD supervisors additional challenges that include the following sub-themes: patient recruitment, writing the first article, agreements and scheduled appointments and two main groups of students, in addition to the main themes. The PhD supervisors reported the clear need and desire for a competence enhancement programme targeting the supervision of PhD students at the Faculty of Health and Medical Sciences. Supervision in the clinical context appeared to require additional competence. The Scientific Ethical Committee for the Capital Region of Denmark. Number: H-3-2010-101, date: 2010.09.29.

Efficacy of primed infusions with high dose ranitidine and omeprazole to maintain high intragastric pH in patients with peptic ulcer bleeding: a prospective randomised controlled study.

PubMed Central

Labenz, J; Peitz, U; Leusing, C; Tillenburg, B; Blum, A L; Börsch, G

1997-01-01

BACKGROUND: In healthy subjects, continuous infusions of high dose ranitidine and omeprazole produce high intragastric pH values. AIM: To test the hypothesis that both drugs also maintain high intragastric pH values in patients with bleeding ulcers. PATIENTS AND METHODS: In two parallel studies, 20 patients with bleeding duodenal ulcers and 20 patients with bleeding gastric ulcers were randomly assigned to receive either ranitidine (0.25 mg/kg/hour after a bolus of 50 mg) or omeprazole (8 mg/hour after a bolus of 80 mg) for 24 hours. Intragastric pH was continuously recorded with a glass electrode placed 5 cm below the cardia. RESULTS: Both drugs rapidly raised the intragastric pH above 6. During the second 12 hour period, however, the percentage of time spent below a pH of 6 was 0.15% with omeprazole and 20.1% with ranitidine (p = 0.0015) in patients with duodenal ulcer; in patients with gastric ulcer it was 0.1% with omeprazole and 46.1% with ranitidine (p = 0.002). CONCLUSIONS: Primed infusions of omeprazole after a bolus produced consistently high intragastric pH values in patients with bleeding peptic ulcers, whereas primed infusions with ranitidine were less effective during the second half of a 24 hour treatment course. This loss of effectiveness may be due to tolerance. PMID:9155573

The Geologic and Geochemical Setting of Lago Fagnano, Tierra del Fuego, Argentina

NASA Astrophysics Data System (ADS)

Tingle, D.; Odle, K.; Knettel, P.; Redding, S.; Perry, E.; Ellins, K.; Ormiston, C.; Dovzak, N.; Anderson, S.

2005-12-01

Lago Fagnano, Tierra del Fuego, Argentina is the largest and southernmost ice-free lake on Earth. The isolated lake is unique because the geographic and geologic context provides information relating to the westerly wind patterns, interaction of multiple water sources (hot springs, glacial meltwater, precipitation, groundwater), and tectonic dynamics along a major transform fault. In March, 2005, four students and three teachers from Boerne High School, south-central Texas joined scientists from the United States, Argentina and Switzerland engaged in a geophysical survey of this lake. Lago Fagnano potentially contains within its sediments an undisturbed record of the geotectonic and global climate variability of past 20,000 years. The science team imaged the lake floor with a boat specially equipped to collect both high resolution data (high frequency), imaging the upper 10-15 meters of the sediment, and long range data (low frequency), penetrating 100 or more meters into the sediment. The group conducted field research of existing tectonic features at the eastern end of Tierra del Fuego, an activity directly tied to the research objectives of the science team. They also collected water and soil samples to assess chemical and isotopic trends in the Lago Fagnano region. The research performed can help to characterize the modern geochemical setting of the lake. Analyses of dissolved oxygen, NH4+, PO42-, pH (water) and N, P, and pH (soils) demonstrate a link between low nutrient levels and low biodiversity (which was confirmed by observation) in Tierra del Fuego. Water and soil data are incorporated into a database to facilitate comparisons to North American samples collected and analyzed during the Boerne High School summer field courses. Twenty-three ^18O and ^D analyses yielded a south-north isotopic trend across the Lago Fagnano region. ^18O and ^D transition from -11.92 to -3.53% and -87.81 to -40.26%, respectively, moving south to the Beagle Channel. These isotopic data, in addition to the soil and water physical and chemical data, provide a snapshot of the geochemical dynamics of the Lago Fagnano watershed. They are valuable because interpretations of paleoclimate will be based on the geochemical history preserved within the lake sediment record. Identification of modern isotopic trends in the Lago Fagnano watershed is helpful for accurate interpretations of the sediment record.

Launching a Geoscience Career: Insights Gained from MS PHD'S Beyond the PhD

NASA Astrophysics Data System (ADS)

Guzman, W. I.; Johnson, A.; Williamson Whitney, V.; Jansma, P. E.; Huggans, M. J.; Ricciardi, L.

2013-05-01

The Beyond the PhD (B-PhD) Professional Development Program is the newest addition to the Minorities Striving and Pursuing Higher Degrees of Success (MS PHD'S®) Professional Development Program in Earth System Science. This exciting new program is designed to facilitate the development of a new community of underrepresented minority (URM) doctoral candidates and recent doctorate degree recipients in Earth system science (ESS)-related fields. Building upon MS PHD'S extensive professional development activities provided to URM undergraduate and graduate students, B-PhD's vision is to encourage and support URM doctoral students and early career PhD's in becoming part of the global workforce. (Since its inception in 2003, MSPHD'S supports 213 participants of which 42 have achieved the doctoral degree and another 71 are enrolled in doctoral programs.) By providing customized support and advocacy for participants, B-PhD facilitates smoother and informed transitions from graduate school to postdoctoral and tenure-track positions, as well as other "first" jobs in academia, government, industry, and non-profit organizations. In 2011, the first conference for 18 doctoral candidate and recent graduates was hosted at the University of Texas at Arlington's (UTA) College of Science. Using a format of guest speakers, brown bag discussions, and interactive breakout sessions, participants engaged in sessions entitled "Toolkits for Success in Academia, Business and Industry, Federal Government and Non-Profits", "Defining Short, Mid and Long Term Career Goals", "Accessing and Refining Skill Sets and Other Door Openers", "International Preparation and Opportunities", "Paying it Forward/Lifting as You Climb", and "Customized Strategies for Next Steps". This presentation will discuss outcomes from this pilot project, the use of social media to track and support ongoing B-PhD activities, and objectives for future B-PhD workshops.

A quantum chemical study for the multichannel reaction PH 2 + PH 2

NASA Astrophysics Data System (ADS)

Pimentel, André S.; Viana, Rommel B.

2007-04-01

The PH 2 + PH 2 multichannel reaction path was proposed in this study. The transition state that connects the reactants to cis-P 2H 2 isomer was found for the first time ever. This process is not allowed to occur at ordinary conditions because of its high energy barrier, 70 kcal mol -1. The PH 2 + PH 2 disproportionation to form the triplet PH 3 radical is an exothermic and spontaneous reaction. The PH 2 + PH 2 reaction may also form the P 2H 4 molecule in the absence of surfaces.

Effects of high medium pH on growth, metabolism and transport in Saccharomyces cerevisiae.

PubMed

Peña, Antonio; Sánchez, Norma Silvia; Álvarez, Helber; Calahorra, Martha; Ramírez, Jorge

2015-03-01

Growth of Saccharomyces cerevisiae stopped by maintaining the pH of the medium in a pH-stat at pH 8.0 or 9.0. Studying its main physiological capacities and comparing cells after incubation at pH 6.0 vs. 8.0 or 9.0, we found that (a) fermentation was moderately decreased by high pH and respiration was similar and sensitive to the addition of an uncoupler, (b) ATP and glucose-6-phosphate levels upon glucose addition increased to similar levels and (c) proton pumping and K(+) transport were also not affected; all this indicating that energy mechanisms were preserved. Growth inhibition at high pH was also not due to a significant lower amino acid transport by the cells or incorporation into proteins. The cell cycle stopped at pH 9.0, probably due to an arrest as a result of adjustments needed by the cells to contend with the changes under these conditions, and microarray experiments showed some relevant changes to this response. © FEMS 2015. All rights reserved. For permissions, please e-mail: journals.permission@oup.com.

Pork Quality Traits According to Postmortem pH and Temperature in Berkshire

PubMed Central

Kim, Tae Wan; Kim, Chul Wook; Yang, Mi Ra; No, Gun Ryoung; Kim, Il-Suk

2016-01-01

This study was performed to investigate the role of pH and temperature postmortem, and to demonstrate the importance of these factors in determining meat quality. Postmortem pH45min (pH at 45 min postmortem or initial pH) via analysis of Pearson’s correlation showed high positive correlation with pH change pHc24 (pH change from pH45min to pH24h postmortem). However, postmortem pH after 24 h (pH24h or ultimate pH) had a high negative correlation with pH change, pHc24, CIE L*, and protein content. Initial temperature postmortem (T1h ) was positively associated with a change in temperature from 45 min to 24 h postmortem (Tc24) and cooking loss, but negatively correlated with water holding capacity. Temperature at 24 h postmortem (T24h) was negatively associated with Tc24. Collectively, these results indicate that higher initial pH was associated with higher pHc24, T1h, and Tc24. However, higher initial pH was associated with a reduction in carcass weight, backfat thickness, CIE a* and b*, water holding capacity, collagen and fat content, drip loss, and cooking loss as well as decreased shear force. In contrast, CIE a* and b*, drip loss, cooking loss, and shear force in higher ultimate pH was showed by a similar pattern to higher initial pH, whereas pHc24, carcass weight, backfat thickness, water holding capacity, fat content, moisture content, protein content, T1h, T24h, and Tc24 were exhibited by completely differential patterns (p<0.05). Therefore, we suggest that initial pH, ultimate pH, and temperatures postmortem are important factors in determining the meat quality of pork. PMID:27499661

Pulmonary hypertension and ventilation during exercise: Role of the pre-capillary component.

PubMed

Caravita, Sergio; Faini, Andrea; Deboeck, Gael; Bondue, Antoine; Naeije, Robert; Parati, Gianfranco; Vachiéry, Jean-Luc

2017-07-01

Excessive exercise-induced hyperventilation and high prevalence of exercise oscillatory breathing (EOB) are present in patients with post-capillary pulmonary hypertension (PH) complicating left heart disease (LHD). Patients with pre-capillary PH have even higher hyperventilation but no EOB. We sought to determine the impact of a pre-capillary component of PH on ventilatory response to exercise in patients with PH and left heart disease. We retrospectively compared patients with idiopathic or heritable pulmonary arterial hypertension (PAH, n = 29), isolated post-capillary PH (IpcPH, n = 29), and combined post- and pre-capillary PH (CpcPH, n = 12). Diastolic pressure gradient (DPG = diastolic pulmonary artery pressure - pulmonary wedge pressure) was used to distinguish IpcPH (DPG <7 mm Hg) from CpcPH (DPG ≥7 mm Hg). Pulmonary vascular resistance (PVR) was higher in PAH, intermediate in CpcPH, and low in IpcPH. All patients with CpcPH but 1 had PVR >3 Wood unit. Exercise-induced hyperventilation (high minute ventilation over carbon dioxide production, low end-tidal carbon dioxide) was marked in PAH, intermediate in CpcPH, and low in IpcPH (p < 0.001) and correlated with DPG and PVR. Prevalence of EOB decreased from IpcPH to CpcPH to PAH (p < 0.001). Patients with CpcPH may have worse hemodynamics than patients with IpcPH and distinct alterations of ventilatory control, consistent with more exercise-induced hyperventilation and less EOB. This might be explained at least in part by the presence and extent of pulmonary vascular disease. Copyright © 2017 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.

Zr/ZrO2 sensors for in situ measurement of pH in high-temperature and -pressure aqueous solutions.

PubMed

Zhang, R H; Zhang, X T; Hu, S M

2008-04-15

The aim of this study is to develop new pH sensors that can be used to test and monitor hydrogen ion activity in hydrothermal conditions. A Zr/ZrO2 oxidation electrode is fabricated for in situ pH measurement of high-temperature aqueous solutions. This sensor responds rapidly and precisely to pH over a wide range of temperature and pressure. The Zr/ZrO2 electrode was made by oxidizing zirconium metal wire with Na2CO3 melt, which produced a thin film of ZrO2 on its surface. Thus, an oxidation-reduction electrode was produced. The Zr/ZrO2 electrode has a good electrochemical stability over a wide range of pH in high-temperature aqueous solutions when used with a Ag/AgCl reference electrode. Measurements of the Zr/ZrO2 sensor potential against a Ag/AgCl reference electrode is shown to vary linearly with pH between temperatures 20 and 200 degrees C. The slope of the potential versus pH at high temperature is slightly below the theoretical value indicated by the Nernst equation; such deviation is attributed to the fact that the sensor is not strictly at equilibrium with the solution to be tested in a short period of time. The Zr/ZrO2 sensor can be calibrated over the conditions that exist in the natural deep-seawater. Our studies showed that the Zr/ZrO2 electrode is a suitable pH sensor for the hydrothermal systems at midocean ridge or other geothermal systems with the high-temperature environment. Yttria-stabilized zirconia sensors have also been used to investigate the pH of hydrothermal fluids in hot springs vents at midocean ridge. These sensors, however, are not sensitive below 200 degrees C. Zr/ZrO2 sensors have wider temperature range and can be severed as good alternative sensors for measuring the pH of hydrothermal fluids.

Salivary pH levels and caries among siblings and parents within families.

PubMed

Basch, Yaffa; Peretz, Benjamin

2013-01-01

High level of caries activity is related to organisms in the dental plaque with high acidogenesis capacity. To test salivary pH in children of the same family and compare it with their caries status. To compare pH levels between children and their parents. To examine the relationship between pH and caries status among children of the same family and their parents. We examined 123 children and adolescents aged 3-18, (73 boys and 50 girls) and 33 adults, (12 men and 21 women), parents of these children. Caries status was examined clinically, using DMF index. Salivary pH measurements were made by a digital pH meter. Among adults, increase in patient age led to increased DMF (p = 0.005). The higher the pH, the lower the DMF (p = 0.037). Among men, DMF was lower by 3 compared to women (p = 0.049). Children's pH correlated with the parents' (p = 0.004). Children's DMF correlated to their pH (p = 0.001). Children's pH was the best predictor of their DMF (R2 = 0.309, p = 0.001). Among children, the higher the pH, the lower the DMFT. Children's pH was the best predictor of their DMF.

McCormick to Aid Frederick National Laboratory in Developing RAS Cancer Genetics Initiative | Frederick National Laboratory for Cancer Research

Cancer.gov

Frank McCormick, Ph.D., director of the Helen Diller Family Comprehensive Cancer Center at the University of California, San Francisco, and associate dean of the UCSF School of Medicine, has signed a consulting agreement with SAIC-Frederick Inc. to w

NATO’s Preparedness for Cyberwar

DTIC Science & Technology

2016-09-01

ARTS IN SECURITY STUDIES EUROPE AND EURASIA from the NAVAL POSTGRADUATE SCHOOL September 2016 Approved by: David Yost, Ph.D...CYBER CASE STUDIES : CYBER ATTACKS AGAINST NATO ALLIES AND PARTNERS .................................................................................33...to thank Dr. Wade Huntley for first stimulating my interest in the academic study of NATO’s cyberwarfare capabilities and readiness. In addition, I

[Environmental Education Units.] Soil Sampling. Stream Profiles. Tree Watching. Plant Puzzles.

ERIC Educational Resources Information Center

Minneapolis Independent School District 275, Minn.

Five of these eleven units describe methods elementary school students can use when studying soil characteristics. Soil nitrogen and water holding capacity tests are included with two techniques for measuring soil pH. Survey methods for soil organisms are suggested. The remaining pamphlets describe diverse activities associated with field…

76 FR 37147 - Notice of Public Meetings for the Eugene District Resource Advisory Committee

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-24

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [ORE000.L58820000 PH0000 LXRSEE990000 HAG11... Land Management, Interior. ACTION: Notice of public meetings. SUMMARY: In accordance with the Emergency Economic Stabilization Act of 2008, Title VI, Secure Schools and Community Self-Determination Program (H.R...

75 FR 22622 - Notice of Public Meetings for the Eugene District, Resource Advisory Committee

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-29

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [L58820000 PH0000 LXRSEE990000 HAG10-0235... Management, Interior. ACTION: Notice of public meetings. SUMMARY: In accordance with the Emergency Economic Stabilization Act of 2008, Title VI, Secure Schools and Community Self-Determination Program (H.R. 1424), the...

Women's studies

NASA Astrophysics Data System (ADS)

Carlowicz, Michael

On March 31, 1997, the Association for Women Geoscientists will award two Chrysalis Scholarships to women who have returned to school after an interruption in their education for a year or longer. The $750 awards will be given to geoscience master's or Ph.D. candidates to cover expenses in finishing their theses.The application deadline is February 28, 1997.

A Hermeneutic Phenomenological Study of Non-Completers in Online Doctor of Education Programs

ERIC Educational Resources Information Center

Wyman, Bernadette Marie

2012-01-01

The chance of an individual completing a traditional doctorate program is 50% (Bowen & Rudenstine, 1992; Council of Graduate Schools Ph.D. Completion Project, 2008; Ivankova & Stick, 2007). Student attrition in online programs is 10% to 20% greater than that of traditional, residential programs (Allen & Seaman, 2010; Carr, 2000; Diaz,…

Integrating Science in Applied Psychology Programs: A Student-Operated Journal

ERIC Educational Resources Information Center

Antonius, Daniel; Brown, Adam D.; Todman, McWelling; Safran, Jeremy D.

2007-01-01

As a requirement of APA accreditation, many PhD programs in applied psychology subscribe to some variant of the scientist-practitioner model. However, critics have argued that integrating science into an applied psychology curriculum may be too challenging a task. This article describes the development of The New School Psychology Bulletin, a…

The Carnegie Project on the Education Doctorate

ERIC Educational Resources Information Center

Perry, Jill Alexa

2015-01-01

Beginning with 21 US schools of education, the Carnegie Project on the Education Doctorate (CPED) has created a network of education faculty who are differentiating the EdD from the PhD in order to better meet the needs of their practitioner-scholar students. Their discussions center on two questions: "What are the knowledge, skills, and…

How Do We Communicate Environmental Ethics? Reflections on Environmental Education from a Kuwaiti Perspective

ERIC Educational Resources Information Center

al-Naki, Khadija

2004-01-01

This paper arises from a PhD research project originally designed to search for innovative ways to stimulate environmental education (EE) in Kuwaiti middle schools. The research has shown that Islam shares similar fundamental principles to those underpinning "ecocentric" perspectives emerging in the West and increasingly thought…

Factors Associated with Success in Doctoral Social Work Education

ERIC Educational Resources Information Center

Johnson-Motoyama, Michelle; Petr, Christopher G.; Mitchell, Felicia M.

2014-01-01

Although admission criteria such as GRE scores and undergraduate GPAs (UGPAs) have been shown to moderately predict success in graduate school for students in other academic disciplines and in MSW programs, no published research has examined factors associated with success in social work PhD programs. This article reports the findings of a pilot…

77 FR 61452 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Designation of Longer...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-09

...; Letter from Daniel G. Weaver, Ph.D., Professor of Finance, Rutgers Business School, dated April 26, 2012; Letter from Amber Anand, Associate Professor of Finance, Syracuse University, dated April 29, 2012; Letter from Albert J. Menkveld, Associate Professor of Finance, VU University Amsterdam, dated May 2...

The Acid Rain Reader.

ERIC Educational Resources Information Center

Stubbs, Harriett S.; And Others

A topic which is often not sufficiently dealt with in elementary school textbooks is acid rain. This student text is designed to supplement classroom materials on the topic. Discussed are: (1) "Rain"; (2) "Water Cycle"; (3) "Fossil Fuels"; (4) "Air Pollution"; (5) "Superstacks"; (6) "Acid/Neutral/Bases"; (7) "pH Scale"; (8) "Acid Rain"; (9)…

Career Opportunities in Physiology: Careers for Physiologists in Departments of Biological and Animal Sciences.

ERIC Educational Resources Information Center

Gregg, Christine M.

1985-01-01

Analyzes data from an American Physiological Society survey on 88 physiology programs not associated with medical schools. Included are enrollment data and data on faculty characteristics, areas of specialization, and doctorates awarded. Indicates that the majority of physiology PhD programs are located within departments of biological sciences.…

Development of a Charged-particle Accumulator Using an RF Confinement Method II

DTIC Science & Technology

2006-08-24

Ryugo Hayano, Ph.D., Professor Department of Physics, Graduate School of Science University of Tokyo 7-3-1 Hongo , Bunkyo-ku...NAME(S) AND ADDRESS(ES) University of Tokyo,7-3-1 Hongo , Bunkyo-ku,Tokyo 113-0033,Japan,JP,113-0033 8. PERFORMING ORGANIZATION REPORT NUMBER AOARD

Reflections on the Current Status of Women in American Higher Education

ERIC Educational Resources Information Center

Robbins, Lillian; Robbins, Edwin

2006-01-01

Since World War II, American women have gained much greater access to higher education, with women now 56% of undergraduates, and approximately half of medical and law school students, as well as attaining 49% of PhD's. Despite their greater representation, women pursuing professional careers still experience considerable stress. At the…

1492--the medical consequences.

PubMed

Camargo, C A

1994-06-01

This discussion was selected from the weekly staff conferences in the Department of Medicine, University of California, San Francisco. Taken from a transcription, it has been edited by Nathan M. Bass, MD, PhD, Associate Professor of Medicine, under the direction of Lloyd H. Smith Jr, MD, Professor of Medicine and Associate Dean in the School of Medicine.

Structural MRI and Cognitive Correlates in Pest-Control Personnel from Gulf War I

DTIC Science & Technology

2010-04-01

Figure (ROCFT; Corwin & Blysma, 1993) Copying a complex geometric design; assess ability to organize and construct Raw Score...workstations at Boston University School of Medicine where they were reconstructed for morphometric analyses by the study imaging expert, Dr. Killiany...conventional structural MRI and morphometric analysis of K. Sullivan, Ph.D

Serum Antibody Biomarkers for ASD

DTIC Science & Technology

2013-10-01

PRINCIPAL INVESTIGATOR: Dwight German, Ph.D. CONTRACTING ORGANIZATION: Univ of Texas Southwestern Medical Center, Dallas TX 75390...REPORT DATE: TYPE OF REPORT: Annual Report PREPARED FOR: U.S. Army Medical Research and Materiel Command...7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Univ. of Texas Southwestern Medical School, Dallas TX 75390 8. PERFORMING ORGANIZATION REPORT

Deans' Perceptions of AACSB-Endorsed Post-Doctoral Bridge Programs

ERIC Educational Resources Information Center

Mauldin, Shawn; McManis, Bruce; Breaux, Kevin

2011-01-01

The Association to Advance Collegiate Schools of Business (AACSB) International has endorsed 5 Post-Doctoral Bridge (PDB) to Business Programs. The objective of these programs is to prepare PhDs from other academic programs for teaching and research careers in business. The authors solicited feedback from deans of AACSB-accredited business schools…

William Russell on Schools in Bulgaria

ERIC Educational Resources Information Center

Popov, Nikolay; Sabic-El-Rayess, Amra

2013-01-01

William Russell became one of the most influential educators in the field of international and comparative education in the first half of the 20th century. In 1914, William Russell obtained his PhD from Teachers College and, within few years, became a prominent figure internationally. He traveled through Europe and taught in Japan and Siberia, as…

Personnel Serving the Severely/Profoundly Handicapped: Professional Preparation and Priorities.

ERIC Educational Resources Information Center

Gisler, Jan; And Others

A survey was designed to collect descriptive information from teachers of severely/profoundly handicapped (S/PH) students in the public schools of Nevada and Utah. Analysis of 59 responses provided information on teacher demographics (including that the majority of teachers were female, held a special education credential and were relatively…

Positive Affect, Negative Affect, and Physiological Hyperarousal among Referred and Nonreferred Youths

ERIC Educational Resources Information Center

Laurent, Jeff; Joiner, Thomas E., Jr.; Catanzaro, Salvatore J.

2011-01-01

The Positive and Negative Affect Scale for Children (PANAS-C) and the Physiological Hyperarousal Scale for Children (PH-C) seem ideal measures for school mental health screenings, because they are theory based, psychometrically sound, and brief. This study provides descriptive information and preliminary cutoff scores in an effort to increase the…

The Limitations of the GRE in Predicting Success in Biomedical Graduate School

PubMed Central

Moneta-Koehler, Liane; Brown, Abigail M.; Petrie, Kimberly A.; Evans, Brent J.; Chalkley, Roger

2017-01-01

Historically, admissions committees for biomedical Ph.D. programs have heavily weighed GRE scores when considering applications for admission. The predictive validity of GRE scores on graduate student success is unclear, and there have been no recent investigations specifically on the relationship between general GRE scores and graduate student success in biomedical research. Data from Vanderbilt University Medical School’s biomedical umbrella program were used to test to what extent GRE scores can predict outcomes in graduate school training when controlling for other admissions information. Overall, the GRE did not prove useful in predicating who will graduate with a Ph.D., pass the qualifying exam, have a shorter time to defense, deliver more conference presentations, publish more first author papers, or obtain an individual grant or fellowship. GRE scores were found to be moderate predictors of first semester grades, and weak to moderate predictors of graduate GPA and some elements of a faculty evaluation. These findings suggest admissions committees of biomedical doctoral programs should consider minimizing their reliance on GRE scores to predict the important measures of progress in the program and student productivity. PMID:28076356

Development of an Integrated ISFET pH Sensor for High Pressure Applications in the Deep-Sea

DTIC Science & Technology

2012-09-30

Measurements in the upper ocean suggest that sensor precision is comparable to the annual pH change due to ocean acidification (Fig. 2). An array of...profiling floats equipped with pH sensors would be capable of directly monitoring the process of ocean acidification . Further refinement of the sensor...Quality of Life The high pressure pH sensor will have direct applications to our understanding of ocean acidification and the impacts on ecosystem

Pharmacoeconomic Education in Egyptian Schools of Pharmacy

PubMed Central

Soliman, Ahmed M.; Hussein, Mustafa; Abdulhalim, Abdulla M.

2013-01-01

Objective. To investigate the status of pharmacoeconomics education in Egyptian schools of pharmacy and compile and construct recommendations on how Egypt and similar countries could improve their educational infrastructure in pharmacoeconomics. Methods. A modified version of a published survey instrument was sent to all schools of pharmacy in Egypt (n= 24). The data were assessed to identify associations between offering pharmacoeconomics education and school characteristics. Results. Usable responses were obtained from 20 schools (response rate: 83%). Only 7 schools offered pharmacoeconomics education, with a median of 20 teaching hours per semester. Among respondents, 4 schools had instructors with some training in pharmacoeconomics and only 1 school had a faculty member with PhD-level training. Only 4 schools offered graduate-level courses in pharmacoeconomics. Eight additional schools expressed interest in teaching pharmacoeconomics in the near future. Having 1 or more faculty members with training in pharmacoeconomics was significantly associated with offering pharmacoeconomics education (p = 0.03). Conclusions. Pharmacoeconomics education in Egypt is still in its infancy and there exists a unique opportunity for well-trained instructors and researchers to fill this gap. Providing structured pharmacoeconomics education to student pharmacists, researchers, and stakeholders can help countries establish an integrated scientific community that can start applying pharmacoeconomic evidence to healthcare decision-making. PMID:23610475

Phosphofructokinase and mitochondria partially explain the high ultimate pH of broiler pectoralis major muscle.

PubMed

Matarneh, Sulaiman K; Yen, Con-Ning; Elgin, Jennifer M; Beline, Mariane; da Luz E Silva, Saulo; Wicks, Jordan C; England, Eric M; Dalloul, Rami A; Persia, Michael E; Omara, Islam I; Shi, Hao; Gerrard, David E

2018-05-01

During postmortem metabolism, muscle pH gradually declines to reach an ultimate pH near 5.6 across most meat species. Yet, broiler pectoralis major (P. major) muscle generates meat with high ultimate pH (pH ∼ 5.9). For better understanding of the underlying mechanism responsible for this phenomenon, we evaluated the involvement of breast muscle chilling on the extent of postmortem metabolism. Broiler breast muscles were either subjected to chilling treatment (control) or left at room temperature (RT) for 120 min. P. major muscle from the RT treatment had lower ultimate pH, greater glycogen degradation and lactate accumulation. While these findings suggest that carcass chilling can contribute to the premature termination of postmortem metabolism, chilling did not fully explain the high ultimate pH of P. major muscle. Our results also revealed that glucose-6-phosphate (G6P) was very low at 24 h, and therefore we hypothesized that G6P was limiting. To test this hypothesis, muscle samples from P. major and porcine longissimus lumborum (LL) muscle were homogenized into a reaction buffer that mimics postmortem glycolysis with or without 0.5 mg/mL isolated mitochondria. While samples containing porcine LL muscle reached the normal level of ultimate pH, P. major muscle samples reached a value similar to that observed in vivo even in the presence of excess G6P, indicating that G6P was not limiting. Mitochondria enhanced the glycolytic flux and pH decline in systems containing muscle from both species. More importantly, however, was that in vitro system containing chicken with mitochondria reached pH value similar to that of samples containing LL muscle without mitochondria. To investigate further, phosphofructokinase (PFK) activity was compared in broiler P. major and porcine LL muscle at different pH values. PFK activity was lower in P. major muscle at pH 7, 6.5, and 6.2 than LL muscle. In conclusion, carcass chilling can partially contribute to the high ultimate pH of broiler P. major muscle, while low PFK activity and mitochondria content limit the flux through glycolysis.

Heterogeneity of T Cell Responses to Pandemic pH1N1 Monovalent Vaccine in HIV-Infected Pregnant Women.

PubMed

Weinberg, Adriana; Muresan, Petronella; Richardson, Kelly; Fenton, Terence; Dominguez, Teresa; Bloom, Anthony; Watts, D Heather; Abzug, Mark J; Nachman, Sharon A; Levin, Myron J

2015-11-01

We investigated the Th1 protective and regulatory T and B cell (Treg and Breg) responses to pH1N1 monovalent influenza vaccine (IIV1) in HIV-infected pregnant women on combination antiretroviral therapy (cART). Peripheral blood mononuclear cells (PBMCs) from 52 study participants were cryopreserved before and after vaccination and analyzed by flow cytometry. pH1N1-specific Th1, Treg, and Breg responses were measured in PBMCs after in vitro stimulation with pH1N1 and control antigen. The cohort analysis did not detect changes in pH1N1-Th1, Treg, or Breg subsets postvaccination. However, individual analyses distinguished subjects who mounted vigorous Th1 responses postvaccination from others who did not. Postvaccination, high pH1N1-Th1 correlated with high pH1N1-Treg and Breg responses, suggesting that low influenza effector responses did not result from excessive vaccine-induced immune regulation. High postvaccination pH1N1-Th1 responses correlated with baseline high PHA- and pH1N1-IFN-γ ELISpot and circulating CD4(+)CD39(+)% and CD8(+)CD39(+)% Treg, with low CD8(+) cell numbers and CD19(+)FOXP3(+)% Breg, but not with CD4(+) cell numbers or HIV viral load. These data highlight the heterogeneity of T cell responses to vaccines in HIV-infected individuals on cART. Predictors of robust Th1 responses to IIV include CD8(+) cell numbers, T cell functionality, and circulating Breg and Treg.

Enhanced volatile fatty acids (VFAs) production in a thermophilic fermenter with stepwise pH increase - Investigation on dissolved organic matter transformation and microbial community shift.

PubMed

Chen, Yun; Jiang, Xie; Xiao, Keke; Shen, Nan; Zeng, Raymond J; Zhou, Yan

2017-04-01

In this study, a mixture of primary and wasted activated sludge was fermented in a semi-continuous reactor aiming for enhanced volatile fatty acids (VFAs) production. The reactor was subjected to a stepwise pH increase from 7 to 10 during approximately 130 days of operation. The result revealed that the maximum acidification was obtained at pH 8.9 (21%) resulting in the maximum production of VFAs (423.22 ± 25.49 mg COD/g VSS), while the maximum hydrolysis efficiency was observed at pH 9.9 (42%). The high pH was effective in releasing dissolved organic matter (DOM) including protein, carbohydrate, building blocks and low molecular weight (LMW) neutrals. More LMW DOMs were released than high molecular weight (HMW) DOMs fractions at higher pH. pH 9.9 favored hydrolysis of HMW DOMs while it did not enhance the acidogenesis of LMW DOMs. The microbial community analysis showed that the relative abundance of phyla Actinobacteria and Proteobacteria increased with the increased pH, which may lead to the maximum hydrolysis at pH 9.9. At pH 8.9, class Clostridia (59.16%) was the most dominant population where the maximum acidification (21%) was obtained. This suggested that the dominance of Clostridia was highly related to acidification extent. The relative abundance of Euryarchaeota decreased significantly from 58% to 2% with increased pH. Copyright © 2017 Elsevier Ltd. All rights reserved.

Control of Molecular Weight Distribution of the Biopolymer Pullulan Produced by the Fungus Aureobasidium Pullulans

DTIC Science & Technology

1987-10-01

Source ( 1 0%) [!H QH (%) (k) Fructose 5.44 3.76 27.0 1122 2.5 Sucrose 5.44 3.69 34.4 895 2.4 Maltose 5. 44 4.08 25.4 881 2. l Corn Syrup 5. 44 3.85...pullulan and found that the uptake of glucose at more acid pH was diverted to the synthesis of extra- cellular pullulan, and that high extracellular...at pH 5.5, pH 6.0, and pH 6.5, Phosphate concentrations of 0.2%-0,4% yielded high MW pullulan at the lower pH level. They reported that using

Excess glycogen does not resolve high ultimate pH of oxidative muscle.

PubMed

England, Eric M; Matarneh, Sulaiman K; Oliver, Emily M; Apaoblaza, Ariel; Scheffler, Tracy L; Shi, Hao; Gerrard, David E

2016-04-01

Skeletal muscle glycogen content can impact the extent of postmortem pH decline. Compared to glycolytic muscles, oxidative muscles contain lower glycogen levels antemortem which may contribute to the higher ultimate pH. In an effort to explore further the participation of glycogen in postmortem metabolism, we postulated that increasing the availability of glycogen would drive additional pH decline in oxidative muscles to equivalent pH values similar to the ultimate pH of glycolytic muscles. Glycolysis and pH declines were compared in porcine longissimus lumborum (glycolytic) and masseter (oxidative) muscles using an in vitro system in the presence of excess glycogen. The ultimate pH of the system containing longissimus lumborum reached a value similar to that observed in intact muscle. The pH decline of the system containing masseter samples stopped prematurely resulting in a higher ultimate pH which was similar to that of intact masseter muscle. To investigate further, we titrated powdered longissimus lumborum and masseter samples in the reaction buffer. As the percentage of glycolytic sample increased, the ultimate pH decreased. These data show that oxidative muscle produces meat with a high ultimate pH regardless of glycogen content and suggest that inherent muscle factors associated with glycolytic muscle control the extent of pH decline in pig muscles. Copyright © 2015 Elsevier Ltd. All rights reserved.

pH tolerance in freshwater bacterioplankton: trait variation of the community as measured by leucine incorporation.

PubMed

Bååth, Erland; Kritzberg, Emma

2015-11-01

pH is an important factor determining bacterial community composition in soil and water. We have directly determined the community tolerance (trait variation) to pH in communities from 22 lakes and streams ranging in pH from 4 to 9 using a growth-based method not relying on distinguishing between individual populations. The pH in the water samples was altered to up to 16 pH values, covering in situ pH ± 2.5 U, and the tolerance was assessed by measuring bacterial growth (Leu incorporation) instantaneously after pH adjustment. The resulting unimodal response curves, reflecting community tolerance to pH, were well modeled with a double logistic equation (mean R(2) = 0.97). The optimal pH for growth (pHopt) among the bacterial communities was closely correlated with in situ pH, with a slope (0.89 ± 0.099) close to unity. The pH interval, in which growth was ≥90% of that at pHopt, was 1.1 to 3 pH units wide (mean 2.0 pH units). Tolerance response curves of communities originating from circum-neutral pH were symmetrical, whereas in high-pH (8.9) and especially in low-pH (<5.5) waters, asymmetric tolerance curves were found. In low-pH waters, decreasing pH was more detrimental for bacterial growth than increasing pH, with a tendency for the opposite for high-pH waters. A pH tolerance index, using the ratio of growth at only two pH values (pH 4 and 8), was closely related to pHopt (R(2) = 0.83), allowing for easy determination of pH tolerance during rapid changes in pH. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

Proton Transport and pH Control in Fungi.

PubMed

Kane, Patricia M

2016-01-01

Despite diverse and changing extracellular environments, fungi maintain a relatively constant cytosolic pH and numerous organelles of distinct lumenal pH. Key players in fungal pH control are V-ATPases and the P-type proton pump Pma1. These two proton pumps act in concert with a large array of other transporters and are highly regulated. The activities of Pma1 and the V-ATPase are coordinated under some conditions, suggesting that pH in the cytosol and organelles is not controlled independently. Genomic studies, particularly in the highly tractable S. cerevisiae, are beginning to provide a systems-level view of pH control, including transcriptional responses to acid or alkaline ambient pH and definition of the full set of regulators required to maintain pH homeostasis. Genetically encoded pH sensors have provided new insights into localized mechanisms of pH control, as well as highlighting the dynamic nature of pH responses to the extracellular environment. Recent studies indicate that cellular pH plays a genuine signaling role that connects nutrient availability and growth rate through a number of mechanisms. Many of the pH control mechanisms found in S. cerevisiae are shared with other fungi, with adaptations for their individual physiological contexts. Fungi deploy certain proton transport and pH control mechanisms not shared with other eukaryotes; these regulators of cellular pH are potential antifungal targets. This review describes current and emerging knowledge proton transport and pH control mechanisms in S. cerevisiae and briefly discusses how these mechanisms vary among fungi.

Proton Transport and pH Control in Fungi

PubMed Central

Kane, Patricia M.

2018-01-01

Despite diverse and changing extracellular environments, fungi maintain a relatively constant cytosolic pH and numerous organelles of distinct lumenal pH. Key players in fungal pH control are V-ATPases and the P-type proton pump Pma1. These two proton pumps act in concert with a large array of other transporters and are highly regulated. The activities of Pma1 and the V-ATPaseare coordinated under some conditions, suggesting that pH in the cytosol and organelles is not controlled independently. Genomic studies, particularly in the highly tractable S. cerevisiae, are beginning to provide a systems-level view of pH control, including transcriptional responses to acid or alkaline ambient pH and definition of the full set of regulators required to maintain pH homeostasis. Genetically encoded pH sensors have provided new insights into localized mechanisms of pH control, as well as highlighting the dynamic nature of pH responses to the extracellular environment. Recent studies indicate that cellular pH plays a genuine signaling role that connects nutrient availability and growth rate through a number of mechanisms. Many of the pH control mechanisms found in S. cerevisiae are shared with other fungi, with adaptations for their individual physiological contexts. Fungi deploy certain proton transport and pH control mechanisms not shared with other eukaryotes; these regulators of cellular pH are potential antifungal targets. This re view describes current and emerging knowledge proton transport and pH control mechanisms in S. cerevisiae and briefly discusses how these mechanisms vary among fungi. PMID:26721270

A novel acidic pH fluorescent probe based on a benzothiazole derivative

NASA Astrophysics Data System (ADS)

Ma, Qiujuan; Li, Xian; Feng, Suxiang; Liang, Beibei; Zhou, Tiqiang; Xu, Min; Ma, Zhuoyi

2017-04-01

A novel acidic pH fluorescent probe 1 based on a benzothiazole derivative has been designed, synthesized and developed. The linear response range covers the acidic pH range from 3.44 to 6.46, which is valuable for pH researches in acidic environment. The evaluated pKa value of the probe 1 is 4.23. The fluorescence enhancement of the studied probe 1 with an increase in hydrogen ions concentration is based on the hindering of enhanced photo-induced electron transfer (PET) process. Moreover, the pH sensor possesses a highly selective response to H+ in the presence of metal ions, anions and other bioactive small molecules which would be interfere with its fluorescent pH response. Furthermore, the probe 1 responds to acidic pH with short response time that was less than 1 min. The probe 1 has been successfully applied to confocal fluorescence imaging in live HeLa cells and can selectively stain lysosomes. All of such good properties prove it can be used to monitoring pH fluctuations in acidic environment with high sensitivity, pH dependence and short response time.

Immobilization of chromate in hyperalkaline waste streams by green rusts and zero-valent iron.

PubMed

Rogers, Christine M; Burke, Ian T; Ahmed, Imad A M; Shaw, Samuel

2014-01-01

Zero-valent iron (ZVI) and green rusts can be used as reductants to convert chromium from soluble, highly toxic Cr(VI) to insoluble Cr(III). This study compared the reduction rates of Cr(VI) by ZVI and two carbonate green rust phases in alkaline/hyperalkaline solutions. Batch experiments were carried out with synthetic chromate solutions at pH 7.7-12.3 and a chromite ore processing residue (COPR) leachate (pH approximately 12.2). Green rust removes chromate from high pH solutions (pH 10-12.5) very rapidly (<400 s). Chromate reduction rates for both green rust phases were consistently higher than for ZVI throughout the pH range studied; the surface area normalized rate constants were two orders of magnitude higher in the COPR leachate solution at pH 12.2. The performances of both green rusts were unaffected by changes in pH. In contrast, ZVI exhibited a marked decline in reduction rate with increasing pH to become almost ineffective above pH12.

Computer simulation of immobilized pH gradients at acidic and alkaline extremes - A quest for extended pH intervals

NASA Technical Reports Server (NTRS)

Mosher, Richard A.; Bier, Milan; Righetti, Pier Giorgio

1986-01-01

Computer simulations of the concentration profiles of simple biprotic ampholytes with Delta pKs 1, 2, and 3, on immobilized pH gradients (IPG) at extreme pH values (pH 3-4 and pH 10-11) show markedly skewed steady-state profiles with increasing kurtosis at higher Delta pK values. Across neutrality, all the peaks are symmetric irrespective of their Delta pK values, but they show very high contribution to the conductivity of the background gel and significant alteration of the local buffering capacity. The problems of skewness, due to the exponential conductivity profiles at low and high pHs, and of gel burning due to a strong electroosmotic flow generated by the net charges in the gel matrix, also at low and high pHs, are solved by incorporating in the IPG gel a strong viscosity gradient. This is generated by a gradient of linear polyacrylamide which is trapped in the gel by the polymerization process.

Comparison of Gingival Health and Salivary Parameters among Autistic and Non-Autistic School Children in Riyadh.

PubMed

Diab, Hafez M; Motlaq, Suha Saeed; Alsharare, Amal; Alshammery, Ashwaq; Alshammery, Nadia; Khawja, Shabnam Gulzar; Shah, Altaf H

2016-10-01

Autism is a neuro-developmental disorder which is manifested as impairment of social interaction, communication and a repetitive behaviour. Autism can obscure dental treatment for the affected patients; furthermore, children with autism commonly have destructive oral habits. The aims of this study were to evaluate the Modified Gingival Index (MGI), Plaque Index (PI), salivary pH and buffering capacity of the saliva among autistic children compared to normal children in Riyadh City that may provide baseline data to enable comparison and future planning of dental services for autistic children. A total of 50 children diagnosed with autism (mean age 8.5 years) were selected from Azzam Autism School, Riyadh City. The control group consisted of 50 non-autistic school children (mean age 8.7 years), gender matched, selected from Outpatient Clinic, Riyadh Colleges of Dentistry and Pharmacy. MGI, PI, salivary pH and salivary buffer capacity tests were done for all participants. The buffering capacity of the stimulated saliva was grouped under 'very low', 'low' and 'normal'. Pearson's Chi square and one way ANOVA were used to find statistical significance if any among the autistic and the normal control group. The results of the study showed that the mean ± standard deviation of MGI, PI and pH of unstimulated resting saliva for autistic group were 1.82 ± 0.65, 1.92 ± 0.35 and 6.8 ± 0.5 respectively. Normal control group had values 1.35 ± 0.85, 1.44 ± 0.43 and 7 ± 0.4 respectively. A statistically significant difference between both groups for all parameters was found. Salivary buffering capacity was found to be normal for the majority among both groups. However, 60% children among the autistic group presented with normal buffering capacity of the stimulated saliva as compared to 70% among the normal control group. However, this difference was not statistically significant (p = 0.544). Children with autism appear to have higher gingival inflammation, poor oral hygiene and a slightly lower salivary pH as compared to healthy control group. Special oral health programmes regarding treatment and maintenance of good oral health should be taken in consideration for autistic children.

Comparison of Gingival Health and Salivary Parameters among Autistic and Non-Autistic School Children in Riyadh

PubMed Central

Diab, Hafez M; Motlaq, Suha Saeed; Alsharare, Amal; Alshammery, Ashwaq; Alshammery, Nadia; Khawja, Shabnam Gulzar

2016-01-01

Introduction Autism is a neuro-developmental disorder which is manifested as impairment of social interaction, communication and a repetitive behaviour. Autism can obscure dental treatment for the affected patients; furthermore, children with autism commonly have destructive oral habits. Aim The aims of this study were to evaluate the Modified Gingival Index (MGI), Plaque Index (PI), salivary pH and buffering capacity of the saliva among autistic children compared to normal children in Riyadh City that may provide baseline data to enable comparison and future planning of dental services for autistic children. Materials and Methods A total of 50 children diagnosed with autism (mean age 8.5 years) were selected from Azzam Autism School, Riyadh City. The control group consisted of 50 non-autistic school children (mean age 8.7 years), gender matched, selected from Outpatient Clinic, Riyadh Colleges of Dentistry and Pharmacy. MGI, PI, salivary pH and salivary buffer capacity tests were done for all participants. The buffering capacity of the stimulated saliva was grouped under ‘very low’, ‘low’ and ‘normal’. Pearson’s Chi square and one way ANOVA were used to find statistical significance if any among the autistic and the normal control group. Results The results of the study showed that the mean ± standard deviation of MGI, PI and pH of unstimulated resting saliva for autistic group were 1.82 ± 0.65, 1.92 ± 0.35 and 6.8 ± 0.5 respectively. Normal control group had values 1.35 ± 0.85, 1.44 ± 0.43 and 7 ± 0.4 respectively. A statistically significant difference between both groups for all parameters was found. Salivary buffering capacity was found to be normal for the majority among both groups. However, 60% children among the autistic group presented with normal buffering capacity of the stimulated saliva as compared to 70% among the normal control group. However, this difference was not statistically significant (p = 0.544). Conclusion Children with autism appear to have higher gingival inflammation, poor oral hygiene and a slightly lower salivary pH as compared to healthy control group. Special oral health programmes regarding treatment and maintenance of good oral health should be taken in consideration for autistic children. PMID:27891471

Introduction to Cosmology, Proceedings of the Polish Astronomical Society volume 4

NASA Astrophysics Data System (ADS)

Biernacka, Monika; Bajan, Katarzyna; Stachowski, Grzegorz; Pollo, Agnieszka

2016-07-01

On 11-23 July 2016, Jan Kochanowski University in Kielce was the host of the Second Cosmological School "Introduction to Cosmology". The main purpose of the School was to provide an introduction to a selection of the most interesting topics in modern cosmology, both in theory and observations. The program included a series of mini-workshops on cosmological simulations, Virtual Observatory database and tools and Spectral Energy Distribution tting. The School was intended for undergraduate, MSc and PhD students, as well as young postdoctoral researchers. The School was co-organized by the Polish Astronomical Society, the Jan Kochanowski University in Kielce, the Jagiellonian University in Cracow, the Nuclear Centre for Nuclear Research and the N. Copernicus Astronomical Center in Warsaw. The Interdisciplinary Centre for Mathematical and Computational Modeling kindly provided us with the possibility to remotely use their computing facilities.

Introduction to Cosmology, Proceedings of the Polish Astronomical Society volume 4

NASA Astrophysics Data System (ADS)

Biernacka, Monika; Bajan, Katarzyna; Stachowski, Grzegorz; Pollo, Agnieszka

2017-08-01

On 11-23 July 2016, Jan Kochanowski University in Kielce was the host of the Second Cosmological School "Introduction to Cosmology". The main purpose of the School was to provide an introduction to a selection of the most interesting topics in modern cosmology, both in theory and observations. The program included a series of mini-workshops on cosmological simulations, Virtual Observatory database and tools and Spectral Energy Distribution tting. The School was intended for undergraduate, MSc and PhD students, as well as young postdoctoral researchers. The School was co-organized by the Polish Astronomical Society, the Jan Kochanowski University in Kielce, the Jagiellonian University in Cracow, the Nuclear Centre for Nuclear Research and the N. Copernicus Astronomical Center in Warsaw. The Interdisciplinary Centre for Mathematical and Computational Modeling kindly provided us with the possibility to remotely use their computing facilities.

Knowledge, Attitudes, and Practices of Nonpharmaceutical Interventions following School Dismissals during the 2009 Influenza A H1N1 Pandemic in Michigan, United States

PubMed Central

Shi, Jianrong; Njai, Rashid; Wells, Eden; Collins, Jim; Wilkins, Melinda; Dooyema, Carrie; Sinclair, Julie; Gao, Hongjiang; Rainey, Jeanette J.

2014-01-01

Background Many schools throughout the United States reported an increase in dismissals due to the 2009 influenza A H1N1 pandemic (pH1N1). During the fall months of 2009, more than 567 school dismissals were reported from the state of Michigan. In December 2009, the Michigan Department of Community Health, in collaboration with the United States Centers for Disease Control and Prevention, conducted a survey to describe the knowledge, attitudes, and practices (KAPs) of households with school-aged children and classroom teachers regarding the recommended use of nonpharmaceutical interventions (NPIs) to slow the spread of influenza. Methods A random sample of eight elementary schools (kindergarten through 5th grade) was selected from each of the eight public health preparedness regions in the state. Within each selected school, a single classroom was randomly identified from each grade (K-5), and household caregivers of the classroom students and their respective teachers were asked to participate in the survey. Results In total, 26% (2,188/8,280) of household caregivers and 45% (163/360) of teachers from 48 schools (of the 64 sampled) responded to the survey. Of the 48 participating schools, 27% (13) experienced a school dismissal during the 2009 fall term. Eighty-seven percent (1,806/2,082) of caregivers and 80% (122/152) of teachers thought that the 2009 influenza A H1N1 pandemic was severe, and >90% of both groups indicated that they told their children/students to use NPIs, such as washing hands more often and covering coughs with tissues, to prevent infection with influenza. Conclusions Knowledge and instruction on the use of NPIs appeared to be high among household caregivers and teachers responding to the survey. Nevertheless, public health officials should continue to explain the public health rationale for NPIs to reduce pandemic influenza. Ensuring this information is communicated to household caregivers and teachers through trusted sources is essential. PMID:24747300

Measurement of the Extracellular pH of Adherently Growing Mammalian Cells with High Spatial Resolution Using a Voltammetric pH Microsensor.

PubMed

Munteanu, Raluca-Elena; Stǎnicǎ, Luciana; Gheorghiu, Mihaela; Gáspár, Szilveszter

2018-05-15

There are only a few tools suitable for measuring the extracellular pH of adherently growing mammalian cells with high spatial resolution, and none of them is widely used in laboratories around the world. Cell biologists very often limit themselves to measuring the intracellular pH with commercially available fluorescent probes. Therefore, we built a voltammetric pH microsensor and investigated its suitability for monitoring the extracellular pH of adherently growing mammalian cells. The voltammetric pH microsensor consisted of a 37 μm diameter carbon fiber microelectrode modified with reduced graphene oxide and syringaldazine. While graphene oxide was used to increase the electrochemically active surface area of our sensor, syringaldazine facilitated pH sensing through its pH-dependent electrochemical oxidation and reduction. The good sensitivity (60 ± 2.5 mV/pH unit), reproducibility (coefficient of variation ≤3% for the same pH measured with 5 different microsensors), and stability (pH drift around 0.05 units in 3 h) of the built voltammetric pH sensors were successfully used to investigate the acidification of the extracellular space of both cancer cells and normal cells. The results indicate that the developed pH microsensor and the perfected experimental protocol based on scanning electrochemical microscopy can reveal details of the pH regulation of cells not attainable with pH sensors lacking spatial resolution or which cannot be reproducibly positioned in the extracellular space.

A Triple-Fluorophore-Labeled Nucleic Acid pH Nanosensor to Investigate Non-viral Gene Delivery.

PubMed

Wilson, David R; Routkevitch, Denis; Rui, Yuan; Mosenia, Arman; Wahlin, Karl J; Quinones-Hinojosa, Alfredo; Zack, Donald J; Green, Jordan J

2017-07-05

There is a need for new tools to better quantify intracellular delivery barriers in high-throughput and high-content ways. Here, we synthesized a triple-fluorophore-labeled nucleic acid pH nanosensor for measuring intracellular pH of exogenous DNA at specific time points in a high-throughput manner by flow cytometry following non-viral transfection. By including two pH-sensitive fluorophores and one pH-insensitive fluorophore in the nanosensor, detection of pH was possible over the full physiological range. We further assessed possible correlation between intracellular pH of delivered DNA, cellular uptake of DNA, and DNA reporter gene expression at 24 hr post-transfection for poly-L-lysine and branched polyethylenimine polyplex nanoparticles. While successful transfection was shown to clearly depend on median cellular pH of delivered DNA at the cell population level, surprisingly, on an individual cell basis, there was no significant correlation between intracellular pH and transfection efficacy. To our knowledge, this is the first reported instance of high-throughput single-cell analysis between cellular uptake of DNA, intracellular pH of delivered DNA, and gene expression of the delivered DNA. Using the nanosensor, we demonstrate that the ability of polymeric nanoparticles to avoid an acidic environment is necessary, but not sufficient, for successful transfection. Copyright © 2017 The American Society of Gene and Cell Therapy. Published by Elsevier Inc. All rights reserved.

pH-adjustment strategy for volatile fatty acid production from high-strength wastewater for biological nutrient removal.

PubMed

Xie, Li; Liu, Hui; Chen, Yin-Guang; Zhou, Qi

2014-01-01

Volatile fatty acid (VFA) production from three types of high-strength organic wastewater (cassava thin stillage, starch wastewater and yellow-wine processing wastewater) were compared. The results showed that cassava thin stillage was the most suitable substrate, based on its high specific VFA production (0.68 g chemical oxygen demand (COD)/g initial soluble chemical oxygen demand (SCOD)) and yield (0.72 g COD/g SCOD) as well as low nutrient content in the substrate and fermented liquid. The acid fermented cassava thin stillage was evaluated and compared with sodium acetate in a sequencing batch reactor system. Total nitrogen removal efficiency was higher with fermented cassava thin stillage than with the sodium acetate. The effects of pH and a pH-adjustment strategy on VFA production and composition were determined using cassava thin stillage. At an initial pH range of 7-11, a relatively high VFA concentration of about 9 g COD/L was obtained. The specific VFA production (g COD/g initial SCOD) increased from 0.27 to 0.47 to 0.67 at pH 8 and from 0.26 to 0.68 to 0.81 at pH 9 (initial pH, interval pH, and constant pH adjustment, respectively). The dominant VFA species changed significantly with the increasing frequency of the pH adjustment. Further studies will examine the metabolic pathways responsible for VFA composition.

Growth strategies to control tapering in Ge nanowires

NASA Astrophysics Data System (ADS)

Periwal, P.; Baron, T.; Gentile, P.; Salem, B.; Bassani, F.

2014-04-01

We report the effect of PH3 on the morphology of Au catalyzed Ge nanowires (NWs). Ge NWs were grown on Si (111) substrate at 400 °C in the presence of PH3, using vapor-liquid-solid method by chemical vapor deposition. We show that high PH3/GeH4 ratio causes passivation at NW surface. At high PH3 concentration phosphorous atoms attach itself on NW surface and form a self-protection coating that prevents conformal growth and leads to taper free nanostructures. However, in case of low PH3 flux the combination of axial and radial growth mechanism occurs resulting in conical structure. We have also investigated axial PH3-intrinsic junctions in Ge NWs. The unusual NW shape is attributed to a combination of catalyzed, uncatalyzed and diffusion induced growth.

Highly Sensitive and Reproducible SERS Sensor for Biological pH Detection Based on a Uniform Gold Nanorod Array Platform.

PubMed

Bi, Liyan; Wang, Yunqing; Yang, Ying; Li, Yuling; Mo, Shanshan; Zheng, Qingyin; Chen, Lingxin

2018-05-09

Conventional research on surface-enhanced Raman scattering (SERS)-based pH sensors often depends on nanoparticle aggregation, whereas the variability in nanoparticle aggregation gives rise to poor repeatability in the SERS signal. Herein, we fabricated a gold nanorod array platform via an efficient evaporative self-assembly method. The platform exhibits great SERS sensitivity with an enhancement factor of 5.6 × 10 7 and maintains excellent recyclability and reproducibility with relative standard deviation (RSD) values of less than 8%. On the basis of the platform, we developed a highly sensitive bovine serum albumin (BSA)-coated 4-mercaptopyridine (4-MPy)-linked (BMP) SERS-based pH sensor to report pH ranging from pH 3.0 to pH 8.0. The intensity ratio variation of 1004 and 1096 cm -1 in 4-MPy showed excellent pH sensitivity, which decreased as the surrounding pH increased. Furthermore, this BMP SERS-based pH sensor was employed to measure the pH value in C57BL/6 mouse blood. We have demonstrated that the pH sensor has great advantages such as good stability, reliability, and accuracy, which could be extended for the design of point-of-care devices.

The influence of pH on the leaching behaviour of inorganic components from municipal solid waste APC residues

DOE Office of Scientific and Technical Information (OSTI.GOV)

Quina, Margarida J.; Bordado, Joao C.M.; Quinta-Ferreira, Rosa M.

2009-09-15

The influence of pH on the leaching behaviour of air pollution control (APC) residues produced in municipal solid waste incineration (MSWI) is addressed in this study. The residue is considered hazardous waste, and in accordance with their chemical properties, the leaching of contaminants into the environment is the main concern. Several leaching tests can be used for research studies or regulatory purposes, where a wide variety of conditions may be tested. Our work deals mainly with the leaching behaviour of toxic heavy metals (Pb, Cd, Zn, Cr, Ni, Cu) and inorganics associated with soluble salts (Na, K, Ca, Cl). Themore » main goal is to obtain an overview of the leachability of APC residues produced in a Portuguese MSWI process. Among the different variables that may have influence on the leaching behaviour, pH of the leachant solution is the most important one, and was evaluated through pH static tests. The acid neutralization capacity (ANC) of the residue was also determined, which is in the range of 6.2-6.8 meq g{sup -1} (for pH = 7) and 10.1-11.6 meq g{sup -1} (for pH = 4). The analysis of the leaching behaviour is particularly important when the leaching is solubility controlled. The amphoteric behaviour of some elements was observed, namely for Pb and Zn, which is characterized through high solubilization at low and high pH and moderate or low solubility at neutral or moderate high pH. The solubility curves for Pb, Cd, Zn, Cr, Ni and Cu as a function of pH were obtained, which are very useful for predicting the leaching behaviour in different scenarios. The solubility of K and Na reveals to be nearly independent of the solution pH and the released amount is mainly availability-controlled. Moreover, the pH static test showed that Cl{sup -} is the most pH-independent species. The APC residue turns out to be a hazardous waste because of the high leaching of lead and chloride. On the other hand, leaching of elements like cadmium, nickel and copper is limited by the high pH of the residue, and as long as the waste keeps its ANC, the risk of mobilization of these elements is low.« less

High pH solubilization and chromatography-based renaturation and purification of recombinant human granulocyte colony-stimulating factor from inclusion bodies.

PubMed

Li, Ming; Fan, Hua; Liu, Jiahua; Wang, Minhong; Wang, Lili; Wang, Chaozhan

2012-03-01

Recombinant human granulocyte colony-stimulating factor (rhG-CSF) is a very efficient therapeutic protein drug which has been widely used in human clinics to treat cancer patients suffering from chemotherapy-induced neutropenia. In this study, rhG-CSF was solubilized from inclusion bodies by using a high-pH solution containing low concentration of urea. It was found that solubilization of the rhG-CSF inclusion bodies greatly depended on the buffer pH employed; alkalic pH significantly favored the solubilization. In addition, when small amount of urea was added to the solution at high pH, the solubilization was further enhanced. After solubilization, the rhG-CSF was renatured with simultaneous purification by using weak anion exchange, strong anion exchange, and hydrophobic interaction chromatography, separately. The results indicated that the rhG-CSF solubilized by the high-pH solution containing low concentration of urea had much higher mass recovery than the one solubilized by 8 M urea when using anyone of the three refolding methods employed in this work. In the case of weak anion exchange chromatography, the high pH solubilized rhG-CSF could get a mass recovery of 73%. The strategy of combining solubilization of inclusion bodies at high pH with refolding of protein using liquid chromatography may become a routine method for protein production from inclusion bodies.

Effect of pH on polyethylene glycol (PEG)-induced silk microsphere formation for drug delivery.

PubMed

Wu, Jianbing; Xie, Xusheng; Zheng, Zhaozhu; Li, Gang; Wang, Xiaoqin; Wang, Yansong

2017-11-01

The effects of changing solution pH in the range of 3.6-10.0 during a one-step silk microsphere preparation process, by mixing silk and polyethylene glycol (PEG), was assessed. The microspheres prepared at low pH (3.6) showed a more homogeneous size (1-3μm) and less porous texture than those prepared at neutral pH. High pH (10.0) inhibited microsphere formation, yielding small and inhomogeneous microspheres. Compared to neutral pH, low pH also increased the content of silk crystalline β-sheet structure from approx. 30% to above 40%. As a result, the microspheres produced at low pH were more thermally stable as well as resistant to chemical (8M urea) and enzymatic (protease XIV) degradation when compared to microspheres prepared at neutral pH. Doxorubicin hydrochloride (DOX) and curcumin (CUR) were successfully loaded in silk microspheres via control of solution pH. The loading efficiency of DOX was approx. 95% at pH7.0 and approx. 60% for CUR at pH3.6, attributed to charge-charge interactions and hydrophobic interactions between the silk and drug molecules, respectively. When PBS, pH7.4, was used as a medium for release studies, the pH3.6 microspheres released both drugs more slowly than the pH7.0 microspheres, likely due to the high content of crystalline β-sheet structure that enhanced drug-silk interactions as well as restricted drug molecule diffusion. Copyright © 2017. Published by Elsevier B.V.

Diurnal and seasonal variations of pH for a year in the western subarctic North Pacific observed by using a hybrid pH sensor

NASA Astrophysics Data System (ADS)

Nakano, Yoshiyuki; Fujiki, Tetsuichi; Kimoto, Katsunori; Miwa, Tetsuya

2017-04-01

Ocean acidification has many far reaching impacts on plankton community in the ocean. There is great need of quality instrumentation to assess and monitor the changing seawater pH. To meet the need, we have developed the in situ high accurate pH sensor (Hybrid pH sensor: HpHS) for the long-term seawater pH monitoring to participate the Wendy Schmidt Ocean health XPRIZE. The HpHS has two types of pH sensors (i.e. potentiometric pH sensor and spectrophotometric pH sensor). The spectrophotometric pH sensor can measure pH correctly and stably, however it needs large power consumption and a lot of reagents in a long period of observation. The pH sensor used m-cresol purple (mCP) as an indicator of pH. On the other hand, although the potentiometric pH sensor is low power consumption and high-speed response (within 10 seconds), drifts in the pH of the potentiometric measurements may possibly occur for a long-term observation. The HpHS can measure in situ pH correctly and stably combining advantage of both pH sensors. The HpHS is correcting the value of the potentiometric pH (measuring frequently) by the value of the spectrophotometric pH (measuring less frequently). It is possible to calibrate in situ with Tris buffer or CRM on the spectrophotometric pH sensor. Therefore, the drifts in the value of potentiometric pH measurements can be compensated using the pH value obtained from the spectrophotometric pH measurements. Thereby, the HpHS can measure accurately the value of pH over a long period of time with low power consumption. In order to understand the seasonal and inter-annual variabilities of biogeochemical cycles and ecosystems, ship-based studies have been carried out since 1997 at time-series station K2 (47oN, 160oE) in the subarctic western North Pacific, which is a region with progression of ocean acidification. However, the ship-based studies of the open ocean have been limited in their ability to conduct high-frequency observations for understanding the biogeochemical cycles and ecosystems. To overcome the problem, we developed a hybrid profiling buoy system. The HpHS was attached to a remote automatic water sampler (200m) in the buoy system in July 2015. We recovered the buoy system in June 2016 and succeeded in observing seawater pH every four hours for a year. Here, we show an overview of the diurnal and seasonal variations of pH for a year at station K2. In addition, we examine a relationship between the pH variations and marine calcifiers recovered by the sediment trap during the same period.

Astrobites: The Astro-ph Reader's Digest For Undergraduates

NASA Astrophysics Data System (ADS)

Kohler, Susanna; Weiss, L. M.; Faesi, C. M.; Astrobites Team

2012-05-01

Astrobites (http://astrobites.com) is a daily blog aimed primarily at undergraduates interested in astrophysical research and written by a team of graduate students located at diverse institutes around the country and Europe. Every day we present a journal article recently posted to astro-ph in a brief format that is accessible to anyone with a general background in the physical sciences. In addition to summarizing new work, Astrobites provides valuable context for readers not yet familiar with the astrophysical literature. Special posts offer career guidance for undergraduates (e.g. applying for an NSF graduate fellowship) and describe personal experiences (e.g. attending an astronomy summer school). We will discuss the Astrobites format and recent readership statistics.

Students’ misconceptions on solubility equilibrium

NASA Astrophysics Data System (ADS)

Setiowati, H.; Utomo, S. B.; Ashadi

2018-05-01

This study investigated the students’ misconceptions of the solubility equilibrium. The participants of the study consisted of 164 students who were in the science class of second year high school. Instrument used is two-tier diagnostic test consisting of 15 items. Responses were marked and coded into four categories: understanding, misconception, understand little without misconception, and not understanding. Semi-structured interviews were carried out with 45 students according to their written responses which reflected different perspectives, to obtain a more elaborated source of data. Data collected from multiple methods were analyzed qualitatively and quantitatively. Based on the data analysis showed that the students misconceptions in all areas in solubility equilibrium. They had more misconceptions such as in the relation of solubility and solubility product, common-ion effect and pH in solubility, and precipitation concept.

Polymer excipients enable sustained drug release in low pH from mechanically strong inorganic geopolymers.

PubMed

Jämstorp, Erik; Yarra, Tejaswi; Cai, Bing; Engqvist, Håkan; Bredenberg, Susanne; Strømme, Maria

2012-01-01

Improving acid resistance, while maintaining the excellent mechanical stability is crucial in the development of a sustained and safe oral geopolymer dosage form for highly potent opioids. In the present work, commercially available Methacrylic acid-ethyl acrylate copolymer, Polyethylene-glycol (PEG) and Alginate polymer excipients were included in dissolved or powder form in geopolymer pellets to improve the release properties of Zolpidem, herein acting as a model drug for the highly potent opioid Fentanyl. Scanning electron microscopy, compression strength tests and drug release experiments, in gastric pH 1 and intestinal pH 6.8 conditions, were performed. The polymer excipients, with an exception for PEG, reduced the drug release rate in pH 1 due to their ability to keep the pellets in shape, in combination with the introduction of an insoluble excipient, and thereby maintain a barrier towards drug diffusion and release. Neither geopolymer compression strength nor the release in pH 6.8 was considerably impaired by the incorporation of the polymer excipients. The geopolymer/polymer composites combine high mechanical strength and good release properties under both gastric and intestinal pH conditions, and are therefore promising oral dosage forms for sustained release of highly potent opioids.

Electrochemical Induced Calcium Phosphate Precipitation: Importance of Local pH

PubMed Central

2017-01-01

Phosphorus (P) is an essential nutrient for living organisms and cannot be replaced or substituted. In this paper, we present a simple yet efficient membrane free electrochemical system for P removal and recovery as calcium phosphate (CaP). This method relies on in situ formation of hydroxide ions by electro mediated water reduction at a titanium cathode surface. The in situ raised pH at the cathode provides a local environment where CaP will become highly supersaturated. Therefore, homogeneous and heterogeneous nucleation of CaP occurs near and at the cathode surface. Because of the local high pH, the P removal behavior is not sensitive to bulk solution pH and therefore, efficient P removal was observed in three studied bulk solutions with pH of 4.0 (56.1%), 8.2 (57.4%), and 10.0 (48.4%) after 24 h of reaction time. While P removal efficiencies are not generally affected by bulk solution pH, the chemical-physical properties of CaP solids collected on the cathode are still related to bulk solution pH, as confirmed by structure characterizations. High initial solution pH promotes the formation of more crystalline products with relatively high Ca/P molar ratio. The Ca/P molar ratio increases from 1.30 (pH 4.0) to 1.38 (pH 8.2) and further increases to 1.55 (pH 10.0). The formation of CaP precipitates was a typical crystallization process, with an amorphous phase formed at the initial stage which then transforms to the most stable crystal phase, hydroxyapatite, which is inferred from the increased Ca/P molar ratio from 1.38 (day 1) to the theoretical 1.76 (day 11) and by the formation of needle-like crystals. Finally, we demonstrated the efficiency of this system for real wastewater. This, together with the fact that the electrochemical method can work at low bulk pH, without dosing chemicals and a need for a separation process, highlights the potential application of the electrochemical method for P removal and recovery. PMID:28872838

Live imaging of intra- and extracellular pH in plants using pHusion, a novel genetically encoded biosensor

PubMed Central

Gjetting, Kisten Sisse Krag; Ytting, Cecilie Karkov; Schulz, Alexander; Fuglsang, Anja Thoe

2012-01-01

Changes in pH are now widely accepted as a signalling mechanism in cells. In plants, proton pumps in the plasma membrane and tonoplast play a key role in regulation of intracellular pH homeostasis and maintenance of transmembrane proton gradients. Proton transport in response to external stimuli can be expected to be finely regulated spatially and temporally. With the ambition to follow such changes live, a new genetically encoded sensor, pHusion, has been developed. pHusion is especially designed for apoplastic pH measurements. It was constitutively expressed in Arabidopsis and targeted for expression in either the cytosol or the apoplast including intracellular compartments. pHusion consists of the tandem concatenation of enhanced green fluorescent protein (EGFP) and monomeric red fluorescent protein (mRFP1), and works as a ratiometric pH sensor. Live microscopy at high spatial and temporal resolution is highly dependent on appropriate immobilization of the specimen for microscopy. Medical adhesive often used in such experiments destroys cell viability in roots. Here a novel system for immobilizing Arabidopsis seedling roots for perfusion experiments is presented which does not impair cell viability. With appropriate immobilization, it was possible to follow changes of the apoplastic and cytosolic pH in mesophyll and root tissue. Rapid pH homeostasis upon external pH changes was reflected by negligible cytosolic pH fluctuations, while the apoplastic pH changed drastically. The great potential for analysing pH regulation in a whole-tissue, physiological context is demonstrated by the immediate alkalinization of the subepidermal apoplast upon external indole-3-acetic acid administration. This change is highly significant in the elongation zone compared with the root hair zone and control roots. PMID:22407646

Live imaging of intra- and extracellular pH in plants using pHusion, a novel genetically encoded biosensor.

PubMed

Gjetting, Kisten Sisse Krag; Ytting, Cecilie Karkov; Schulz, Alexander; Fuglsang, Anja Thoe

2012-05-01

Changes in pH are now widely accepted as a signalling mechanism in cells. In plants, proton pumps in the plasma membrane and tonoplast play a key role in regulation of intracellular pH homeostasis and maintenance of transmembrane proton gradients. Proton transport in response to external stimuli can be expected to be finely regulated spatially and temporally. With the ambition to follow such changes live, a new genetically encoded sensor, pHusion, has been developed. pHusion is especially designed for apoplastic pH measurements. It was constitutively expressed in Arabidopsis and targeted for expression in either the cytosol or the apoplast including intracellular compartments. pHusion consists of the tandem concatenation of enhanced green fluorescent protein (EGFP) and monomeric red fluorescent protein (mRFP1), and works as a ratiometric pH sensor. Live microscopy at high spatial and temporal resolution is highly dependent on appropriate immobilization of the specimen for microscopy. Medical adhesive often used in such experiments destroys cell viability in roots. Here a novel system for immobilizing Arabidopsis seedling roots for perfusion experiments is presented which does not impair cell viability. With appropriate immobilization, it was possible to follow changes of the apoplastic and cytosolic pH in mesophyll and root tissue. Rapid pH homeostasis upon external pH changes was reflected by negligible cytosolic pH fluctuations, while the apoplastic pH changed drastically. The great potential for analysing pH regulation in a whole-tissue, physiological context is demonstrated by the immediate alkalinization of the subepidermal apoplast upon external indole-3-acetic acid administration. This change is highly significant in the elongation zone compared with the root hair zone and control roots.

Regulation of arsenic mobility on basaltic glass surfaces by speciation and pH.

PubMed

Sigfusson, Bergur; Meharg, Andrew A; Gislason, Sigurdur R

2008-12-01

The importance of geothermal energy as a source for electricity generation and district heating has increased over recent decades. Arsenic can be a significant constituent of the geothermal fluids pumped to the surface during power generation. Dissolved As exists in different oxidation states, mainly as As(III) and As(V), and the charge of individual species varies with pH. Basaltic glass is one of the most important rock types in many high-temperature geothermal fields. Static batch and dynamic column experiments were combined to generate and validate sorption coefficients for As(III) and As(V) in contact with basaltic glass at pH 3-10. Validation was carried out by two empirical kinetic models and a surface complexation model (SCM). The SCM provided a better fit to the experimental column data than kinetic models at high pH values. However, in certain circumstances, an adequate estimation of As transport in the column could not be attained without incorporation of kinetic reactions. The varying mobility with pH was due to the combined effects of the variable charge of the basaltic glass with the pH point of zero charge at 6.8 and the individual As species as pH shifted, respectively. The mobility of As(III) decreased with increasing pH. The opposite was true for As(V), being nearly immobile at pH 3 to being highly mobile at pH 10. Incorporation of appropriate sorption constants, based on the measured pH and Eh of geothermal fluids, into regional groundwater-flow models should allow prediction of the As(III) and As(V) transport from geothermal systems to adjacent drinking water sources and ecosystems.

A Dual-Mode Large-Arrayed CMOS ISFET Sensor for Accurate and High-Throughput pH Sensing in Biomedical Diagnosis.

PubMed

Huang, Xiwei; Yu, Hao; Liu, Xu; Jiang, Yu; Yan, Mei; Wu, Dongping

2015-09-01

The existing ISFET-based DNA sequencing detects hydrogen ions released during the polymerization of DNA strands on microbeads, which are scattered into microwell array above the ISFET sensor with unknown distribution. However, false pH detection happens at empty microwells due to crosstalk from neighboring microbeads. In this paper, a dual-mode CMOS ISFET sensor is proposed to have accurate pH detection toward DNA sequencing. Dual-mode sensing, optical and chemical modes, is realized by integrating a CMOS image sensor (CIS) with ISFET pH sensor, and is fabricated in a standard 0.18-μm CIS process. With accurate determination of microbead physical locations with CIS pixel by contact imaging, the dual-mode sensor can correlate local pH for one DNA slice at one location-determined microbead, which can result in improved pH detection accuracy. Moreover, toward a high-throughput DNA sequencing, a correlated-double-sampling readout that supports large array for both modes is deployed to reduce pixel-to-pixel nonuniformity such as threshold voltage mismatch. The proposed CMOS dual-mode sensor is experimentally examined to show a well correlated pH map and optical image for microbeads with a pH sensitivity of 26.2 mV/pH, a fixed pattern noise (FPN) reduction from 4% to 0.3%, and a readout speed of 1200 frames/s. A dual-mode CMOS ISFET sensor with suppressed FPN for accurate large-arrayed pH sensing is proposed and demonstrated with state-of-the-art measured results toward accurate and high-throughput DNA sequencing. The developed dual-mode CMOS ISFET sensor has great potential for future personal genome diagnostics with high accuracy and low cost.

Interactions of calcium and fulvic acid at the goethite-water interface

NASA Astrophysics Data System (ADS)

Weng, Li Ping; Koopal, Luuk K.; Hiemstra, Tjisse; Meeussen, Johannes C. L.; Van Riemsdijk, Willem H.

2005-01-01

Interactions of calcium and fulvic acid (Strichen ) with the surface of goethite were studied with batch and titration experiments. The mutual influence of the interactions on the adsorption of fulvic acid, calcium ions and protons were examined. Adsorption of the fulvic acid to goethite decreased with increase in pH (pH range 3-11). Addition of Ca (1.0 mM) at intermediate and high pH significantly enhanced the adsorption of fulvic acid. Compared to the adsorption to pure goethite, the presence of fulvic acid enhanced the adsorption of Ca significantly. In comparison to the simple linear sum of Ca bound to fulvic acid and goethite, the interactions between goethite and fulvic acid led to a reduced adsorption of Ca at low pH and an enhanced adsorption at high pH. With the adsorption of fulvic acid, protons were released at low pH and coadsorbed at high pH. When Ca was added, fewer protons were released at low pH and fewer coadsorbed at high pH. The experimental results can be adequately described using a surface complexation model, the Ligand and Charge Distribution (LCD) model, in which the CD-MUSIC model for ion adsorption to mineral oxides and the NICA model for ion binding to humics are integrated. In the model calculations, adequate descriptions of the ternary system data (Ca-fulvic acid-goethite) were obtained with parameters derived from three binary systems (fulvic acid-goethite, Ca-goethite and Ca-fulvic acid) without further adjustment. The model calculations suggest that the interactions between Ca and fulvic acid at the surface of goethite are mainly due to the electrostatic effects.

[The construction of cell-penetrating peptide R8 and pH sensitive cleavable polyethylene glycols co-modified liposomes].

PubMed

Zhang, Li; Wang, Yang; Gao, Hui-le; He, Qin

2015-06-01

The purpose of the study is to construct R8 peptide (RRRRRRRR) and pH sensitive polyethylene glycols (PEG) co-modified liposomes (Cl-Lip) and utilize them in breast cancer treatment. The co-modified liposomes were prepared with soybean phospholipid, cholesterol, DSPE-PEG2K-R8 and PEG5K-Hz-PE (pH sensitive PEG). The size and zeta potential of Cl-Lip were also characterized. The in vitro experiment demonstrated that the Cl-Lip had high serum stability in 50% fetal bovine serum. The cellular uptake of Cl-Lip under different pre-incubated conditions was evaluated on 4T1 cells. And the endocytosis pathway, lysosome escape ability and tumor spheroid penetration ability were also evaluated. The results showed the particle size of the Cl-Lip was (110.4 ± 5.2) nm, PDI of the Cl-Lip was 0.207 ± 0.039 and zeta potential of the Cl-Lip was (-3.46 ± 0.05) mV. The cellular uptake of Cl-Lip on 4T1 cells was pH sensitive, as the cellular uptake of Cl-Lip pre-incubated in pH 6.0 was higher than that of pH 7.4 under each time point. The main endocytosis pathways of Cl-Lip under pH 6.0 were micropinocytosis and energy-dependent pathway. At the same time, the Cl-Lip with pre-incubation in pH 6.0 had high lysosome escape ability and high tumor spheroid penetration ability. All the above results demonstrated that the Cl-Lip we constructed had high pH sensitivity and is a promising drug delivery system.

Preliminary study on optimization of pH, oxidant and catalyst dose for high COD content: solar parabolic trough collector

PubMed Central

2013-01-01

In the present study, solar photocatalytic oxidation has been investigated through laboratory experiments as an alternative to conventional secondary treatment for the organic content reduction of high COD wastewater. Experiments have been performed on synthetic high COD wastewater for solar photocatalytic oxidation using a parabolic trough reactor. Parameters affecting the oxidation of organics have been investigated. The experimental design followed the sequence of dark adsorption studies of organics, followed by photolytic studies (in absence of catalyst) and finally photocatalytic studies in presence and absence of additional oxidant (H2O2). All the experimental studies have been performed at pH values of 2, 4, 6,8,10 and the initial pH value of the wastewater (normal pH). For photocatalytic studies, TiO2 has been used as a photocatalyst. Optimization of catalyst dose, pH and H2O2 concentration has been done. Maximum reduction of organic content was observed at the normal pH value of the wastewater (pH = 6.8). The reaction rate was significantly enhanced in presence of hydrogen peroxide. The optimum pH other than the Normal was in the alkaline range. Acidic pH was not found to be favourable for organic content reduction. pH was found to be a dominant factor affecting reaction rate even in presence of H2O2 as an additional oxidant. Also, the solar detoxification process was effective in treating a waste with a COD level of more than 7500 mg/L, which is a otherwise a difficult waste to treat. It can therefore be used as a treatment step in the high organic wastewater treatment during the primary stage also as it effectively reduces the COD content by 86%. PMID:23369352

Campylobacter, Salmonella, and Escherichia coli on broiler carcasses subjected to a high pH scald and low pH postpick chlorine dip.

PubMed

Berrang, M E; Windham, W R; Meinersmann, R J

2011-04-01

The objective of this study was to determine the individual and combined effects of a high pH scald and a postpick chlorine dip on bacteria present on broiler carcasses. In each of 3 replications, a flock was sampled at several sites within a commercial broiler processing plant. Carcasses were sampled by whole carcass rinse before and after treated scalding at mean pH 9.89 or control scalding at mean pH 6.88. Other carcasses from the same flock run on both the treated and control scald lines were collected and sampled before and after a chlorine dip tank operated at mean total chlorine level of 83.3 mg/kg and pH 6.04. Rinses were cultured for numbers of Campylobacter and Escherichia coli and presence or absence of Salmonella. High pH scald was more effective than standard scald to lessen the prevalence and numbers of Campylobacter on broiler carcasses; a lower prevalence was maintained through the postpick chlorine dip tank. The pH of the scald tank made no difference in numbers of E. coli recovered from broiler carcasses at any tested point on the processing line. High pH scald was not more effective than standard scald to lessen Salmonella prevalence. Furthermore, it is unclear why the postpick chlorine dip effectively lessened Salmonella prevalence on only the control scald line. Although no evidence exists that these treatments have an additive effect when used in series, each treatment shows some promise individually. Further optimization may result in more effective decontamination of broiler carcasses.

Wigner in Hungary

NASA Astrophysics Data System (ADS)

Marx, George

2002-04-01

Eugene P. Wigner was born into a well-to-do family in Budapest 100 years ago. .He attended the Fasori Lutheran Gymnasium, which educated - among others - John von Neumann, and John Harsanyi,Nobel-laureate in economics. Wigner was influenced by his math teacher, László Rátz who taught calculus in high school. World War I, revolutions and counter/revolutions, kingdom, republic, soviet type council republic followed each other in dizzying sequence, so Wigner decided to continue his university studies in Berlin, where quantum mechanics was discussed and developed in the 1920s. After his Ph.D. Wigner worked in Budapest and in Berlin, and he elaborated the foundations of quantum mechanics based on symmetry principles. He wrote his book on symmetries during a summer holiday in Hungary, and this later brought him the Nobel Prize. Wigner moved to the U.S. in 1930, where he enjoyed the excellent working conditions and recognition. He revisited his homeland only in the 1970s, where his ideas about the future attracted huge audiences at the Academy of Sciences, at universities, and in the Physical Society. He received high honors from his home country - a bit belatedly. The principal focus of his attention was the quantum-mechanical concept of measurement, the role of human consciousness. But even in his last years, in the 1980s, he most enjoyed his visits to high schools - attending physics classes, discussing the future of science in human society with teachers and students.

Effects of anatomy and diet on gastrointestinal pH in rodents.

PubMed

Kohl, Kevin D; Stengel, Ashley; Samuni-Blank, Michal; Dearing, M Denise

2013-04-01

The pH of the gastrointestinal tract can have profound influences on digestive processes. Rodents exhibit wide variation in both stomach morphology and dietary strategies, both of which may influence gut pH. Various rodent species have evolved bilocular (or semi-segmented) stomachs that may allow for more microbial growth compared to unilocular (single-chambered) stomachs. Additionally, herbivory has evolved multiple times in rodents. The high dietary fiber typical of an herbivorous diet is known to induce secretion of bicarbonate in the gut. We predicted that stomach segmentation might facilitate the separation of contents in the proximal chamber from that of the gastric stomach, facilitating a chemical environment suitable to microbial growth. To investigate the effect of stomach anatomy and diet on gut pH, several species of rodent with varying stomach morphology were fed either a high or low-fiber diet for 7 days, and pH of the proximal stomach, gastric stomach, small intestine, and cecum were measured. We discovered that rodents with bilocular stomach anatomy maintained a larger pH gradient between the proximal and gastric stomach compartments, and were able to achieve a lower absolute gastric pH compared to those with unilocular stomachs. Dietary fiber increased the pH of the small intestine, but not in any other gut regions. The stomach pH data supports the century old hypothesis that bilocular stomach anatomy creates an environment in the proximal stomach that is suitable for microbial growth. Additionally, the alkaline small intestinal pH on a high fiber diet may enhance digestion. Copyright © 2013 Wiley Periodicals, Inc.

High serum uric acid level and low urine pH as predictors of metabolic syndrome: a retrospective cohort study in a Japanese urban population.

PubMed

Hara, Shigeko; Tsuji, Hiroshi; Ohmoto, Yuki; Amakawa, Kazuhisa; Hsieh, Shiun Dong; Arase, Yasuji; Nakajima, Hiromu

2012-02-01

The objective of this study was to evaluate whether hyperuricemia, acidic urine, or their combination predicts metabolic syndrome (MetS). In study 1, 69,094 subjects who received a general health checkup between 1985 and 2005 were included in a cross-sectional study of serum uric acid (SUA) and urine pH in relation to MetS. In study 2, the association of SUA and urine pH with MetS development over a 5-year period was evaluated in 5617 subjects with body mass index less than 25 kg/m(2) at the first examination. In study 1, higher SUA and lower urine pH were both positively correlated to MetS status (P < .001). The combination of high SUA and low urine pH was significantly associated with higher MetS prevalence compared with the combination of low SUA and high urine pH (odds ratio, 3.383; 95% confidence interval [CI], 3.034-3.784 in men; odds ratio, 4.000; 95% CI, 2.992-5.452 in women). In study 2, the top quartile of SUA levels was associated with higher MetS development compared with the bottom quartile during the 5-year period in men (hazard ratio [HR], 1.793; 95% CI, 1.084-2.966; P = .023). In women, the HR was 3.732 (95% CI, 0.391-35.62; P = .252) for the upper vs the lower half of SUA levels. For urine pH, the HR was 1.955 (95% CI, 1.089-3.509; P = .025) for the bottom vs the top quartile in men. A likelihood ratio test confirmed that high SUA and low urine pH act synergistically in the development of MetS. High SUA, low urine pH, and their combination are predictive risk factors for MetS development. Copyright © 2012 Elsevier Inc. All rights reserved.

Conditions of Mytilus edulis extracellular body fluids and shell composition in a pH-treatment experiment: Acid-base status, trace elements and δ11B

NASA Astrophysics Data System (ADS)

Heinemann, Agnes; Fietzke, Jan; Melzner, Frank; BöHm, Florian; Thomsen, JöRn; Garbe-SchöNberg, Dieter; Eisenhauer, Anton

2012-01-01

Mytilus edulis were cultured for 3 months under six different seawater pCO2 levels ranging from 380 to 4000 μatm. Specimen were taken from Kiel Fjord (Western Baltic Sea, Germany) which is a habitat with high and variable seawater pCO2 and related shifts in carbonate system speciation (e.g., low pH and low CaCO3 saturation state). Hemolymph (HL) and extrapallial fluid (EPF) samples were analyzed for pH and total dissolved inorganic carbon (CT) to calculate pCO2 and [HCO3-]. A second experiment was conducted for 2 months with three different pCO2 levels (380, 1400 and 4000 μatm). Boron isotopes (δ11B) were investigated by LA-MC-ICP-MS (Laser Ablation-Multicollector-Inductively Coupled Plasma-Mass Spectrometry) in shell portions precipitated during experimental treatment time. Additionally, elemental ratios (B/Ca, Mg/Ca and Sr/Ca) in the EPF of specimen from the second experiment were measured via ICP-OES (Inductively Coupled Plasma-Optical Emission Spectrometry). Extracellular pH was not significantly different in HL and EPF but systematically lower than ambient water pH. This is due to high extracellular pCO2 values, a prerequisite for metabolic CO2 excretion. No accumulation of extracellular [HCO3-] was measured. Elemental ratios (B/Ca, Mg/Ca and Sr/Ca) in the EPF increased slightly with pH which is in accordance with increasing growth and calcification rates at higher seawater pH values. Boron isotope ratios were highly variable between different individuals but also within single shells. This corresponds to a high individual variability in fluid B/Ca ratios and may be due to high boron concentrations in the organic parts of the shell. The mean δ11B value shows no trend with pH but appears to represent internal pH (EPF) rather than ambient water pH.

A newly high alkaline lipase: an ideal choice for application in detergent formulations

PubMed Central

2011-01-01

Background Bacterial lipases received much attention for their substrate specificity and their ability to function in extreme environments (pH, temperature...). Many staphylococci produced lipases which were released into the culture medium. Reports of thermostable lipases from Staphylococcus sp. and active in alkaline conditions are not previously described. Results A newly soil-isolated Staphylococcus sp. strain ESW secretes an induced lipase in the culture medium. The effects of temperature, pH and various components in a detergent on the activity and stability of Staphylococcus sp. lipase (SL1) were studied in a preliminary evaluation for use in detergent formulation solutions. The enzyme was highly active over a wide range of pH from 9.0 to 13.0, with an optimum at pH 12.0. The relative activity at pH 13.0 was about 60% of that obtained at pH 12.0. It exhibited maximal activity at 60°C. This novel lipase, showed extreme stability towards non-ionic and anionic surfactants after pre-incubation for 1 h at 40°C, and relative stability towards oxidizing agents. Additionally, the crude enzyme showed excellent stability and compatibility with various commercial solid and liquid detergents. Conclusions These properties added to the high activity in high alkaline pH make this novel lipase an ideal choice for application in detergent formulations. PMID:22123072

They Throw Spears: Reconciliation through Music

ERIC Educational Resources Information Center

Moore, Jane

2013-01-01

"They throw Spears" was written as part of the research for my PhD at the University of Sydney. The study was conducted in two primary schools: one in a remote area in the Northern Territory (NT) and one in an urban setting in Tasmania. It was conducted in 2009 and investigated Indigenous and non-Indigenous student, non-Indigenous…

Critical Thinking and ICT Integration in a Western Australian Secondary School

ERIC Educational Resources Information Center

McMahon, Graham

2009-01-01

This study examined the relationship between students working in a technology-rich environment and their development of higher order thinking skills. Based on a PhD thesis, which examined a greater range of relationships than can be reported here, this article focuses on developing critical thinking skills within a technology-rich environment.…

The Oral History of Evaluation: The Professional Development of Joseph Wholey

ERIC Educational Resources Information Center

Miller, Robin Lin; Caracelli, Valerie

2013-01-01

Joseph S. Wholey is Professor Emeritus in the University of Southern California's (USC) School of Public Policy, Planning, and Development. He received his BA from Catholic University, Phi Beta Kappa and his MA in mathematics and PhD in philosophy from Harvard University. His work focuses on the use of strategic planning, performance measurement,…

Higher Inductive Types as Homotopy-Initial Algebras

DTIC Science & Technology

2016-08-01

Higher Inductive Types as Homotopy-Initial Algebras Kristina Sojakova CMU-CS-16-125 August 2016 School of Computer Science Carnegie Mellon University...talk at the Workshop on Logic, Language, Information and Computation (WoLLIC 2011). 1, 2.1 [38] M. Warren. Homotopy-Theoretic Aspects of Constructive Type Theory. PhD thesis, Carnegie Mellon University, 2008. 1 143

William Wolfgang Brickman, 1913-86.

ERIC Educational Resources Information Center

Parker, Franklin

William Wolfgang Brickman, founding member and President, 1956-59, of the Comparative and International Education Society, died June 22, 1986, in a Philadelphia hospital leukemia unit. Born June 30, 1913, in New York City, he attended city schools and earned B.A. and M.S. degrees at City College, a New York University Ph.D. and an honorary M.A.…

Contracting Out Government Procurement Functions: An Analysis

DTIC Science & Technology

2008-01-15

Services Council and the Logistics Management Institute (LMI); papers presented at the NPS Annual Acquisition Research Symposium; and student and...supported the funding of the research presented herein. Reproduction of all or part of this report is authorized. The report was prepared by...School of Business & Public Policy Released by: ________________________________ Dan C. Boger, Ph.D. Acting Dean of Research

Back to the Future

ERIC Educational Resources Information Center

D'Eon, Marcel

2004-01-01

I attended all 42 hours of classes in the Cardiovascular System Course in order to help the course coordinator set the examination. What makes this unusual is that I am not a physician. As a PhD educator supporting faculty and the educational programs at our medical school I became a learner as well as a co-course co-coordinator. Attending all the…

Professional Development for Transformational Technology Integration: An Experimental Study of In-Service Teachers' Self-Perceptions of Technological Pedagogical and Content Knowledge

ERIC Educational Resources Information Center

Tachau, Elena M.

2017-01-01

Professional Development for Transformational Technology Integration: An Experimental Study of In-Service Teachers' Self-Perceptions of Technological Pedagogical and Content Knowledge Elena M. Tachau Drexel University Chairperson: Brian K. Smith, Ph.D. The rapid advancement of technology tasks K-12 schools with providing professional development…

ChemDuino: Adapting Arduino for Low-Cost Chemical Measurements in Lecture and Laboratory

ERIC Educational Resources Information Center

Kubínova´, S?te?pa´nka; S?le´gr, Jan

2015-01-01

In everyday praxis, we often need demonstration measuring devices (thermometers, pH meters, etc.), with large enough displays to be easily readable from every point in the classroom. Here, we present some of the capabilities of the Arduino platform for the school environment. This microprocessor board can be used for inexpensive construction of…

What's Slithering around on Your School Grounds? Transforming Student Awareness of Reptile & Amphibian Diversity

ERIC Educational Resources Information Center

Tomasek, Terry M.; Matthews, Catherine E.; Hall, Jeff

2005-01-01

The protocols used in a research project on amphibian and reptile diversity at Cool Springs Environmental Education Center near New Bern, North Carolina is described. An increasing or stable number of amphibians and reptiles would indicate that the forest has a balance of invertebrates, leaf litter, moisture, pH, debris, burrows and habitat…

Taking Advantage of External Funding for Air Force Officer PH.D. Candidates at Civilian Universities

DTIC Science & Technology

2009-12-01

5_01738_table_4.pdf . 32 John M. Braxton and Robert C. Nordvall , “Selective Liberal Arts Colleges: Higher Quality as well as Higher Prestige?” The Journal...Requirements and Utilizing Assets.‖ Master‘s thesis, Naval Postgraduate School, 1986. Braxton, John M. and Robert C. Nordvall . ―Selective Liberal Arts

Taking Advantage of External Funding for Air Force Officer Ph.D. Candidates at Civilian Universities

DTIC Science & Technology

2009-12-01

5_01738_table_4.pdf . 32 John M. Braxton and Robert C. Nordvall , “Selective Liberal Arts Colleges: Higher Quality as well as Higher Prestige?” The Journal...Requirements and Utilizing Assets.‖ Master‘s thesis, Naval Postgraduate School, 1986. Braxton, John M. and Robert C. Nordvall . ―Selective Liberal Arts

1492—The Medical Consequences

PubMed Central

Camargo, Carlos A.

1994-01-01

This discussion was selected from the weekly staff conferences in the Department of Medicine, University of California, San Francisco. Taken from a transcription, it has been edited by Nathan M. Bass, MD, PhD, Associate Professor of Medicine, under the direction of Lloyd H. Smith Jr, MD, Professor of Medicine and Associate Dean in the School of Medicine. Images PMID:7519808

Postdoctorals vs. Non-Postdoctorals: Career Performance Differentials Within Academic Medicine.

ERIC Educational Resources Information Center

Fribush, Stuart L.; Larson, Thomas A.

The research methodology developed in this paper was intended to shed some light on the question of career performance differentials within academic medicine between persons who have undergone postdoctoral training and those who have not. Compared were two groups of medical school faculty members (including M. D.'s and Ph.D.'s). One group included…

Structural Evaluation of Riveted Spillway Gates

DTIC Science & Technology

1994-06-01

EngineerWaewyExemntstaio) RE8-C-p .•i1 8c.- Tcnclrpr ERC-3 TA7~o W34noREM-C-4 1. Hda ulcgte.2 Silays --~mm Dttm esloing-n adontubcation -if Evlain...A7 steel also was restricted to open- hearth or electric furnace production, and excluded the older acid -besse- mer production. These compositional...alternately wet and dry cycles. d. pH of the river water. Corrosion usually occurs at low pH (highly acidic conditions) and at high pH (highly alkaline

Parastomal hernias after radical cystectomy and ileal conduit diversion

PubMed Central

Donahue, Timothy F.

2016-01-01

Parastomal hernia, defined as an "incisional hernia related to an abdominal wall stoma", is a frequent complication after conduit urinary diversion that can negatively impact quality of life and present a clinically significant problem for many patients. Parastomal hernia (PH) rates may be as high as 65% and while many patients are asymptomatic, in some series up to 30% of patients require surgical intervention due to pain, leakage, ostomy appliance problems, urinary obstruction, and rarely bowel obstruction or strangulation. Local tissue repair, stoma relocation, and mesh repairs have been performed to correct PH, however, long-term results have been disappointing with recurrence rates of 30%–76% reported after these techniques. Due to high recurrence rates and the potential morbidity of PH repair, efforts have been made to prevent PH development at the time of the initial surgery. Randomized trials of circumstomal prophylactic mesh placement at the time of colostomy and ileostomy stoma formation have shown significant reductions in PH rates with acceptably low complication profiles. We have placed prophylactic mesh at the time of ileal conduit creation in patients at high risk for PH development and found it to be safe and effective in reducing the PH rates over the short-term. In this review, we describe the clinical and radiographic definitions of PH, the clinical impact and risk factors associated with its development, and the use of prophylactic mesh placement for patients undergoing ileal conduit urinary diversion with the intent of reducing PH rates. PMID:27437533

Professor Eugen Cerkovnikov (1904-1985): the founder of the Chemical and Biochemical Institute of the Rijeka University School of Medicine.

PubMed

Milin, Cedomila

2008-01-01

Professor Eugen Cerkovnikov, PhD (Kamenska, Russia, 1904- Rijeka, Croatia 1985) graduated in chemical technology from the Faculty of Engineering in Zagreb in 1929. His first job was at the School of Medicine in Paris in 1930, and then he moved to Zagreb to the Department of Organic Chemistry of the Faculty of Engineering run by our Nobel Prize winner Vladimir Prelog (1935-1938). There he took his PhD degree with a dissertation on piperidine gamma derivatives. From 1938 to 1947 he was a research associate at an institute established by the pharmaceutical company Kastel (later Pliva). This is when he became a lecturer at the Faculty of Pharmacy in Zagreb and the first director of the Institute of Organic Chemistry, established in 1946/47. In 1948 he became reader, and in 1956 (full) professor. In 1957 he moved to the newly established School of Medicine in Rijeka, and set up the Institute of Chemistry and Biochemistry. He ran the Institute until retirement in 1975. He was the second dean of the Rijeka University School of Medicine and a pioneer of quantum chemistry and medical cybernetics in undergraduate and (post)graduate courses. His scientific work consists of over 200 papers published at home and abroad, 60 professional papers, 20 book reviews, three works of translation, and 27 volumes of lecture notes. In 1958, professor Cerkovnikov established the Croatian Chemical Society and the Rijeka and Istria branches of the nation's Association of Chemists and Chemical Engineers, chairing them until 1974. In addition, he was one of the founding fathers, and the first chair of the Health Culture Studies Association in Rijeka (that preceded today's Croatian Scientific Society for the History of Health Culture), established in 1965.

Profile of Public Health Leadership.

PubMed

Little, Ruth Gaskins; Greer, Annette; Clay, Maria; McFadden, Cheryl

2016-01-01

Public health leaders play pivotal roles in ensuring the population health for our nation. Since 2000, the number of schools of public health has almost doubled. The scholarly credentials for leaders of public health in academic and practice are important, as they make decisions that shape the future public health workforce and important public health policies. This research brief describes the educational degrees of deans of schools of public health and state health directors, as well as their demographic profiles, providing important information for future public health leadership planning. Data were extracted from a database containing information obtained from multiple Web sites including academic institution Web sites and state government Web sites. Variables describe 2 sets of public health leaders: academic deans of schools of public health and state health directors. Deans of schools of public health were 73% males and 27% females; the PhD degree was held by 40% deans, and the MD degree by 33% deans. Seventy percent of deans obtained their terminal degree more than 35 years ago. State health directors were 60% males and 40% females. Sixty percent of state health directors had an MD degree, 4% a PhD degree, and 26% no terminal degree at all. Sixty-four percent of state health directors received their terminal degree more than 25 years ago. In addition to terminal degrees, 56% of deans and 40% of state health directors held MPH degrees. The findings call into question competencies needed by future public health professionals and leadership and the need to clarify further the level of public health training and degree type that should be required for leadership qualifications in public health.