Sample records for phonation threshold flow

  1. Estimating phonation threshold pressure.

    PubMed

    Fisher, K V; Swank, P R

    1997-10-01

    Phonation threshold pressure (PTP) is the minimum subglottal pressure required to initiate vocal fold oscillation. Although potentially useful clinically, PTP is difficult to estimate noninvasively because of limitations to vocal motor control near the threshold of soft phonation. Previous investigators observed, for example, that trained subjects were unable to produce flat, consistent oral pressure peaks during/pae/syllable strings when they attempted to phonate as softly as possible (Verdolini-Marston, Titze, & Druker, 1990). The present study aimed to determine if nasal airflow or vowel context affected phonation threshold pressure as estimated from oral pressure (Smitheran & Hixon, 1981) in 5 untrained female speakers with normal velopharyngeal and voice function. Nasal airflow during /p/occlusion was observed for 3 of 5 participants when they attempted to phonate near threshold pressure. When the nose was occluded, nasal airflow was reduced or eliminated during /p/;however, individuals then evidenced compensatory changes in glottal adduction and/or respiratory effort that may be expected to alter PTP estimates. Results demonstrate the importance of monitoring nasal flow (or the flow zero point in undivided masks) when obtaining PTP measurements noninvasively. Results also highlight the need to pursue improved methods for noninvasive estimation of PTP.

  2. Glottal flow through a two-mass model: comparison of Navier-Stokes solutions with simplified models.

    PubMed

    de Vries, M P; Schutte, H K; Veldman, A E P; Verkerke, G J

    2002-04-01

    A new numerical model of the vocal folds is presented based on the well-known two-mass models of the vocal folds. The two-mass model is coupled to a model of glottal airflow based on the incompressible Navier-Stokes equations. Glottal waves are produced using different initial glottal gaps and different subglottal pressures. Fundamental frequency, glottal peak flow, and closed phase of the glottal waves have been compared with values known from the literature. The phonation threshold pressure was determined for different initial glottal gaps. The phonation threshold pressure obtained using the flow model with Navier-Stokes equations corresponds better to values determined in normal phonation than the phonation threshold pressure obtained using the flow model based on the Bernoulli equation. Using the Navier-Stokes equations, an increase of the subglottal pressure causes the fundamental frequency and the glottal peak flow to increase, whereas the fundamental frequency in the Bernoulli-based model does not change with increasing pressure.

  3. What happens during vocal warm-up?

    PubMed

    Elliot, N; Sundberg, J; Gramming, P

    1995-03-01

    Most singers prefer to warm up their voices before performing. Although the subjective effect is often considerable, the underlying physiological effects are largely unknown. Because warm-up tends to increase blood flow in muscles, it seems likely that vocal warm-up might induce decreased viscosity in the vocal folds. According to the theory of vocal-fold vibration, such a decrease should lead to a lower phonation threshold pressure. In this investigation the effect of vocal warm-up on the phonation threshold pressure was examined in a group of male and female singers. The effect varied considerably between subjects, presumably because the vocal-fold viscosity was not a dominating factor for the phonation-threshold pressure.

  4. Optimal glottal configuration for ease of phonation.

    PubMed

    Lucero, J C

    1998-06-01

    Recent experimental studies have shown the existence of optimal values of the glottal width and convergence angle, at which the phonation threshold pressure is minimum. These results indicate the existence of an optimal glottal configuration for ease of phonation, not predicted by the previous theory. In this paper, the origin of the optimal configuration is investigated using a low dimensional mathematical model of the vocal fold. Two phenomena of glottal aerodynamics are examined: pressure losses due to air viscosity, and air flow separation from a divergent glottis. The optimal glottal configuration seems to be a consequence of the combined effect of both factors. The results agree with the experimental data, showing that the phonation threshold pressure is minimum when the vocal folds are slightly separated in a near rectangular glottis.

  5. Multi-parameter analysis of titanium vocal fold medializing implant in an excised larynx model

    PubMed Central

    Witt, Rachel E.; Hoffman, Matthew R.; Friedrich, Gerhard; Rieves, Adam L.; Schoepke, Benjamin J.; Jiang, Jack J.

    2010-01-01

    Objective Evaluate the efficacy of the titanium vocal fold medializing implant (TVFMI) for the treatment of unilateral vocal fold paralysis (UVFP) based on acoustic, aerodynamic, and mucosal wave measurements in an excised larynx setup. Methods Measurements were recorded on eight excised canine larynges with simulated UVFP before and after medialization with the TVFMI. Results Phonation threshold flow (PTF) and phonation threshold power (PTW) decreased significantly after medialization (p<0.001; p=0.008). Phonation threshold pressure (PTP) also decreased, but this difference was not significant (p=0.081). Percent jitter and percent shimmer decreased significantly after medialization (p=0.005; p=0.034). Signal to noise ratio (SNR) increased significantly (p=0.05). Differences in mucosal wave characteristics were discernable, but not significant. Phase difference between the normal and paralyzed vocal fold and amplitude of the paralyzed vocal fold decreased (p=0.15; p=0.78). Glottal gap decreased significantly (p=0.004). Conclusions The TVFMI was effective in achieving vocal fold medialization, improving vocal aerodynamic and acoustic characteristics of phonation significantly and mucosal wave characteristics discernibly. This study provides objective, quantitative support for the use of the TVFMI in improving vocal function in patients with unilateral vocal fold paralysis. PMID:20336924

  6. Effects on Vocal Fold Collision and Phonation Threshold Pressure of Resonance Tube Phonation with Tube End in Water

    ERIC Educational Resources Information Center

    Enflo, Laura; Sundberg, Johan; Romedahl, Camilla; McAllister, Anita

    2013-01-01

    Purpose: Resonance tube phonation in water (RTPW) or in air is a voice therapy method successfully used for treatment of several voice pathologies. Its effect on the voice has not been thoroughly studied. This investigation analyzes the effects of RTPW on collision and phonation threshold pressures (CTP and PTP), the lowest subglottal pressure…

  7. Characteristics of phonation onset in a two-layer vocal fold model.

    PubMed

    Zhang, Zhaoyan

    2009-02-01

    Characteristics of phonation onset were investigated in a two-layer body-cover continuum model of the vocal folds as a function of the biomechanical and geometric properties of the vocal folds. The analysis showed that an increase in either the body or cover stiffness generally increased the phonation threshold pressure and phonation onset frequency, although the effectiveness of varying body or cover stiffness as a pitch control mechanism varied depending on the body-cover stiffness ratio. Increasing body-cover stiffness ratio reduced the vibration amplitude of the body layer, and the vocal fold motion was gradually restricted to the medial surface, resulting in more effective flow modulation and higher sound production efficiency. The fluid-structure interaction induced synchronization of more than one group of eigenmodes so that two or more eigenmodes may be simultaneously destabilized toward phonation onset. At certain conditions, a slight change in vocal fold stiffness or geometry may cause phonation onset to occur as eigenmode synchronization due to a different pair of eigenmodes, leading to sudden changes in phonation onset frequency, vocal fold vibration pattern, and sound production efficiency. Although observed in a linear stability analysis, a similar mechanism may also play a role in register changes at finite-amplitude oscillations.

  8. Phonation Threshold Pressure Measurement With a Semi-Occluded Vocal Tract

    PubMed Central

    Titze, Ingo R.

    2015-01-01

    Purpose The purpose of this article was to determine if a semi-occluded vocal tract could be used to measure phonation threshold pressure. This is in contrast to the shutter technique, where an alternation between a fully occluded tract and an unoccluded tract is used. Method Five male and 5 female volunteers phonated through a thin straw held between the lips. Oral pressure behind the lips was measured. Mathematical predictions of phonation threshold pressures were compared to the measured ones over a range of frequencies. Results It was shown that, for a 2.5-mm diameter straw, phonation threshold pressures were obtainable over a 2-octave range of fundamental frequency by all volunteers. In magnitude, the pressures agreed with the 0.2–0.5 kPa values obtained in previous investigations. Sensitivity to viscoelastic and geometric properties of the vocal folds was generally not compromised with greater oral impedance, but some differences were predicted theoretically in contrast to an open mouth configuration. Conclusion Because phonation threshold pressure is always dependent on vocal tract interaction, it may be advantageous to choose an exact and fixed oral semi-occlusion for the measurement and interpret the results in light of the known acoustic load. PMID:19641082

  9. Resonance Tube Phonation in Water-the Effect of Tube Diameter and Water Depth on Back Pressure and Bubble Characteristics at Different Airflows.

    PubMed

    Wistbacka, Greta; Andrade, Pedro Amarante; Simberg, Susanna; Hammarberg, Britta; Södersten, Maria; Švec, Jan G; Granqvist, Svante

    2018-01-01

    Resonance tube phonation with tube end in water is a voice therapy method in which the patient phonates through a glass tube, keeping the free end of the tube submerged in water, creating bubbles. The purpose of this experimental study was to determine flow-pressure relationship, flow thresholds between bubble types, and bubble frequency as a function of flow and back volume. A flow-driven vocal tract simulator was used for recording the back pressure produced by resonance tubes with inner diameters of 8 and 9 mm submerged at water depths of 0-7 cm. Visual inspection of bubble types through video recording was also performed. The static back pressure was largely determined by the water depth. The narrower tube provided a slightly higher back pressure for a given flow and depth. The amplitude of the pressure oscillations increased with flow and depth. Depending on flow, the bubbles were emitted from the tube in three distinct types with increasing flow: one by one, pairwise, and in a chaotic manner. The bubble frequency was slightly higher for the narrower tube. An increase in back volume led to a decrease in bubble frequency. This study provides data on the physical properties of resonance tube phonation with the tube end in water. This information will be useful in future research when looking into the possible effects of this type of voice training. Copyright © 2018 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  10. Phonation Threshold Pressure Measurement with a Semi-Occluded Vocal Tract

    ERIC Educational Resources Information Center

    Titze, Ingo R.

    2009-01-01

    Purpose: The purpose of this article was to determine if a semi-occluded vocal tract could be used to measure phonation threshold pressure. This is in contrast to the shutter technique, where an alternation between a fully occluded tract and an unoccluded tract is used. Method: Five male and 5 female volunteers phonated through a thin straw held…

  11. The Effect of Vocal Fold Inferior Surface Hypertrophy on Voice Function in Excised Canine Larynges.

    PubMed

    Wang, Ruiqing; Bao, Huijing; Xu, Xinlin; Piotrowski, David; Zhang, Yu; Zhuang, Peiyun

    2017-08-18

    This study aimed to explore the changes in vocal fold inferior surface hypertrophy (VFISH) on vocal fold vibration by aerodynamic and acoustic analysis. The present study allows us to gain new insights into the subglottal convergence angle (SCA), which will change with VFISH. The study is prospective, and designed for repeated measures with each excised canine larynx serving as own control. Three degrees of VFISH, initial, mild, and severe, were simulated by injecting different doses of fructose injections into the inferior surface of the vocal folds of 10 excised canine larynges. Computed tomographic images of the larynx were gathered, and three-dimensional models of the airway and vocal folds were reconstructed using the Mimics software. The SCA was measured from the reconstructed models. Phonation threshold flow (PTF), phonation threshold pressure (PTP), and mean flow rate (MFR) were recorded directly in the excised canine larynx phonation setup. Glottal resistance (GR), sound pressure level (SPL), fundamental frequency (F0), and formants 1-4 (F1-4) were measured when subglottal pressure (P sub ) was at 1.5 kPa or 2.5 kPa, separately. Using ordinary one-way analysis of variance, we compared the aerodynamic outcomes and voice quality among the three groups of hypertrophy. The SCA, PTP, and PTF increased with the degree of VFISH. When the P sub was controlled at 1.5 kPa or 2.5 kPa, F0 also increased significantly with the degree of VFISH of the excised canine larynges. The MFR, GR, SPL, and F1-4 had little change between the three groups and were not significantly different. The VFISH makes onset phonation more difficult, increases the SCA, and increases the F0 in sustained phonation. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  12. Aeroelastic Model of Vocal-Fold Vibrating Element for Studying the Phonation Threshold

    NASA Astrophysics Data System (ADS)

    Horáček, J.; Švec, J. G.

    2002-10-01

    An original theoretical model for vibration onset of the vocal folds in the air-flow coming from the human subglottal tract is designed, which allows studying the influence of the physical properties of the vocal folds (e.g., geometrical shape, mass, viscosity) on their vibration characteristics (such as the natural frequencies, mode shapes of vibration and the thresholds of instability). The mathematical model of the vocal fold is designed as a simplified dynamic system of two degrees of freedom (rotation and translation) vibrating on an elastic foundation in the wall of a channel conveying air. An approximate unsteady one-dimensional flow theory for the inviscid incompressible fluid is presented for the phonatory air-flow. A generally defined shape of the vocal-fold surface is considered for expressing the unsteady aerodynamic forces in the glottis. The parameters of the mechanical part of the model, i.e., the mass, stiffness and damping matrices, are related to the geometry and material density of the vocal folds as well as to the fundamental natural frequency and damping known from experiments. The coupled numerical solution yields the vibration characteristics (natural frequencies, damping and mode shapes of vibration), including the instability thresholds of the aeroelastic system. The vibration characteristics obtained from the coupled numerical solution of the system appear to be in reasonable qualitative agreement with the physiological data and clinical observations. The model is particularly suitable for studying the phonation threshold, i.e., the onset of vibration of the vocal folds.

  13. Vocal warm-up increases phonation threshold pressure in soprano singers at high pitch.

    PubMed

    Motel, Tamara; Fisher, Kimberly V; Leydon, Ciara

    2003-06-01

    Vocal warm-up is thought to optimize singing performance. We compared effects of short-term, submaximal, vocal warm-up exercise with those of vocal rest on the soprano voice (n = 10, ages 19-21 years). Dependent variables were the minimum subglottic air pressure required for vocal fold oscillation to occur (phonation threshold pressure, Pth), and the maximum and minimum phonation fundamental frequency. Warm-up increased Pth for high pitch phonation (p = 0.033), but not for comfortable (p = 0.297) or low (p = 0.087) pitch phonation. No significant difference in the maximum phonation frequency (p = 0.193) or minimum frequency (p = 0.222) was observed. An elevated Pth at controlled high pitch, but an unchanging maximum and minimum frequency production suggests that short-term vocal exercise may increase the viscosity of the vocal fold and thus serve to stabilize the high voice.

  14. Phonation threshold pressure: Comparison of calculations and measurements taken with physical models of the vocal fold mucosa

    PubMed Central

    Fulcher, Lewis P.; Scherer, Ronald C.

    2011-01-01

    In an important paper on the physics of small amplitude oscillations, Titze showed that the essence of the vertical phase difference, which allows energy to be transferred from the flowing air to the motion of the vocal folds, could be captured in a surface wave model, and he derived a formula for the phonation threshold pressure with an explicit dependence on the geometrical and biomechanical properties of the vocal folds. The formula inspired a series of experiments [e.g., R. Chan and I. Titze, J. Acoust. Soc. Am 119, 2351–2362 (2006)]. Although the experiments support many aspects of Titze’s formula, including a linear dependence on the glottal half-width, the behavior of the experiments at the smallest values of this parameter is not consistent with the formula. It is shown that a key element for removing this discrepancy lies in a careful examination of the properties of the entrance loss coefficient. In particular, measurements of the entrance loss coefficient at small widths done with a physical model of the glottis (M5) show that this coefficient varies inversely with the glottal width. A numerical solution of the time-dependent equations of the surface wave model shows that adding a supraglottal vocal tract lowers the phonation threshold pressure by an amount approximately consistent with Chan and Titze’s experiments. PMID:21895097

  15. Phonation threshold pressure: comparison of calculations and measurements taken with physical models of the vocal fold mucosa.

    PubMed

    Fulcher, Lewis P; Scherer, Ronald C

    2011-09-01

    In an important paper on the physics of small amplitude oscillations, Titze showed that the essence of the vertical phase difference, which allows energy to be transferred from the flowing air to the motion of the vocal folds, could be captured in a surface wave model, and he derived a formula for the phonation threshold pressure with an explicit dependence on the geometrical and biomechanical properties of the vocal folds. The formula inspired a series of experiments [e.g., R. Chan and I. Titze, J. Acoust. Soc. Am 119, 2351-2362 (2006)]. Although the experiments support many aspects of Titze's formula, including a linear dependence on the glottal half-width, the behavior of the experiments at the smallest values of this parameter is not consistent with the formula. It is shown that a key element for removing this discrepancy lies in a careful examination of the properties of the entrance loss coefficient. In particular, measurements of the entrance loss coefficient at small widths done with a physical model of the glottis (M5) show that this coefficient varies inversely with the glottal width. A numerical solution of the time-dependent equations of the surface wave model shows that adding a supraglottal vocal tract lowers the phonation threshold pressure by an amount approximately consistent with Chan and Titze's experiments. © 2011 Acoustical Society of America

  16. Vocal power and pressure–flow relationships in excised tiger larynges

    PubMed Central

    Titze, Ingo R.; Fitch, W. Tecumseh; Hunter, Eric J.; Alipour, Fariborz; Montequin, Douglas; Armstrong, Douglas L.; McGee, JoAnn; Walsh, Edward J.

    2010-01-01

    Despite the functional importance of loud, low-pitched vocalizations in big cats of the genus Panthera, little is known about the physics and physiology of the mechanisms producing such calls. We investigated laryngeal sound production in the laboratory using an excised-larynx setup combined with sound-level measurements and pressure–flow instrumentation. The larynges of five tigers (three Siberian or Amur, one generic non-pedigreed tiger with Bengal ancestry and one Sumatran), which had died of natural causes, were provided by Omaha's Henry Doorly Zoo over a five-year period. Anatomical investigation indicated the presence of both a rigid cartilaginous plate in the arytenoid portion of the glottis, and a vocal fold fused with a ventricular fold. Both of these features have been confusingly termed ‘vocal pads’ in the previous literature. We successfully induced phonation in all of these larynges. Our results showed that aerodynamic power in the glottis was of the order of 1.0 W for all specimens, acoustic power radiated (without a vocal tract) was of the order of 0.1 mW, and fundamental frequency ranged between 20 and 100 Hz when a lung pressure in the range of 0–2.0 kPa was applied. The mean glottal airflow increased to the order of 1.0 l s–1 per 1.0 kPa of pressure, which is predictable from scaling human and canine larynges by glottal length and vibrational amplitude. Phonation threshold pressure was remarkably low, on the order of 0.3 kPa, which is lower than for human and canine larynges phonated without a vocal tract. Our results indicate that a vocal fold length approximately three times greater than that of humans is predictive of the low fundamental frequency, and the extraordinarily flat and broad medial surface of the vocal folds is predictive of the low phonation threshold pressure. PMID:21037066

  17. Vocal power and pressure-flow relationships in excised tiger larynges.

    PubMed

    Titze, Ingo R; Fitch, W Tecumseh; Hunter, Eric J; Alipour, Fariborz; Montequin, Douglas; Armstrong, Douglas L; McGee, Joann; Walsh, Edward J

    2010-11-15

    Despite the functional importance of loud, low-pitched vocalizations in big cats of the genus Panthera, little is known about the physics and physiology of the mechanisms producing such calls. We investigated laryngeal sound production in the laboratory using an excised-larynx setup combined with sound-level measurements and pressure-flow instrumentation. The larynges of five tigers (three Siberian or Amur, one generic non-pedigreed tiger with Bengal ancestry and one Sumatran), which had died of natural causes, were provided by Omaha's Henry Doorly Zoo over a five-year period. Anatomical investigation indicated the presence of both a rigid cartilaginous plate in the arytenoid portion of the glottis, and a vocal fold fused with a ventricular fold. Both of these features have been confusingly termed 'vocal pads' in the previous literature. We successfully induced phonation in all of these larynges. Our results showed that aerodynamic power in the glottis was of the order of 1.0 W for all specimens, acoustic power radiated (without a vocal tract) was of the order of 0.1 mW, and fundamental frequency ranged between 20 and 100 Hz when a lung pressure in the range of 0-2.0 kPa was applied. The mean glottal airflow increased to the order of 1.0 l s(-1) per 1.0 kPa of pressure, which is predictable from scaling human and canine larynges by glottal length and vibrational amplitude. Phonation threshold pressure was remarkably low, on the order of 0.3 kPa, which is lower than for human and canine larynges phonated without a vocal tract. Our results indicate that a vocal fold length approximately three times greater than that of humans is predictive of the low fundamental frequency, and the extraordinarily flat and broad medial surface of the vocal folds is predictive of the low phonation threshold pressure.

  18. Direct numerical simulation of human phonation

    NASA Astrophysics Data System (ADS)

    Saurabh, Shakti; Bodony, Daniel

    2016-11-01

    A direct numerical simulation study of the generation and propagation of the human voice in a full-body domain is conducted. A fully compressible fluid flow model, anatomically representative vocal tract geometry, finite deformation model for vocal fold (VF) motion and a fully coupled fluid-structure interaction model are employed. The dynamics of the multi-layered VF tissue with varying stiffness are solved using a quadratic finite element code. The fluid-solid domains are coupled through a boundary-fitted interface and utilize a Poisson equation-based mesh deformation method. A new inflow boundary condition, based upon a quasi-1D formulation with constant sub-glottal volume velocity, linked to the VF movement, has been adopted. Simulations for both child and adult phonation were performed. Acoustic characteristics obtained from these simulation are consistent with expected values. A sensitivity analysis based on VF stiffness variation is undertaken and sound pressure level/fundamental frequency trends are established. An evaluation of the data against the commonly-used quasi-1D equations suggest that the latter are not sufficient to model phonation. Phonation threshold pressures are measured for several VF stiffness variations and comparisons to clinical data are carried out. Supported by the National Science Foundation (CAREER Award Number 1150439).

  19. An evaluation of the effects of three laryngeal lubricants on phonation threshold pressure (PTP).

    PubMed

    Roy, Nelson; Tanner, Kristine; Gray, Steven D; Blomgren, Michael; Fisher, Kimberly V

    2003-09-01

    Clinicians frequently offer advice to performers and voice-disordered patients aimed ostensibly to manipulate the water content and/or viscosity of the mucus blanket covering the vocal folds. To evaluate the relative effects of three potential laryngeal lubricants on phonatory function (ie, water, Mannitol--an osmotic agent, and Entertainer's Secret Throat Relief (Kli Corp., Carmel, IN)--a glycerin-based product), phonation threshold pressure (PTP) was measured in 18 healthy, vocally normal female participants twice before (baseline) and then four times after 2 ml of each substance were nebulized. PTP is the minimum subglottal pressure required to initiate vocal fold oscillation, and the lowering of PTP is assumed to correspond to physiologically more efficient phonation and reduced phonatory effort. Over a 3-week period, participants were tested on three separate occasions (at 1-week intervals). On each occasion, a different nebulized treatment was administered. PTP for both comfortable and high fundamental frequency productions was measured using an oral pressure-flow system (Perci-Sars, MicroTronics Corp., Chapel Hill, NC). Analysis of the results revealed that Mannitol, an agent that encourages osmotic water flux to the luminal airway surface, lowered PTP immediately after its administration (ie, p = 0.071, for high-pitched productions only). However, the duration of its PTP lowering effect was less than 20 minutes. The other two substances did not demonstrate any significant postadministration effect on PTP.

  20. Multi-parameter comparison of injection laryngoplasty, medialization laryngoplasty, and arytenoid adduction in an excised larynx model

    PubMed Central

    Hoffman, Matthew R.; Witt, Rachel E.; Chapin, William J.; McCulloch, Timothy M.; Jiang, Jack J.

    2010-01-01

    Objective Evaluate the effect of injection laryngoplasty (IL), medialization laryngoplasty (ML), and ML combined with arytenoid adduction (ML-AA) on acoustic, aerodynamic, and mucosal wave measurements in an excised larynx setup. Methods Measurements were recorded for eight excised canine larynges with simulated unilateral vocal fold paralysis (UVFP) before and after vocal fold injection with Cymetra. A second set of eight larynges was used to evaluate medialization laryngoplasty using a Silastic implant without and with arytenoid adduction. Results IL and ML led to comparable decreases in phonation threshold flow (PTF), phonation threshold pressure (PTP), and phonation threshold power (PTW). ML-AA led to significant decreases in PTF (p=0.008), PTP (p=0.008), and PTW (p=0.008). IL and ML led to approximately equal decreases in percent jitter and percent shimmer. ML-AA caused the greatest increase in signal to noise ratio (SNR). ML-AA discernibly decreased frequency (p=0.059); a clear trend was not observed for IL or ML. IL significantly reduced mucosal wave amplitude (p=0.002), while both ML and ML-AA increased it. All procedures significantly decreased glottal gap, with the most dramatic effects observed after ML-AA (p=0.004). Conclusions ML-AA led to the greatest improvements in phonatory parameters. IL was comparable to ML aerodynamically and acoustically, but caused detrimental changes to the mucosal wave. Incremental improvements in parameters recorded from the same larynx were observed after ML and ML-AA. To ensure optimal acoustic outcome, the arytenoid must be correctly rotated. This study provides objective support for the combined ML-AA procedure in tolerant patients. Evidence based medicine level Not applicable – animal study. PMID:20213797

  1. Effects of mucosal loading on vocal fold vibration.

    PubMed

    Tao, Chao; Jiang, Jack J

    2009-06-01

    A chain model was proposed in this study to examine the effects of mucosal loading on vocal fold vibration. Mucosal loading was defined as the loading caused by the interaction between the vocal folds and the surrounding tissue. In the proposed model, the vocal folds and the surrounding tissue were represented by a series of oscillators connected by a coupling spring. The lumped masses, springs, and dampers of the oscillators modeled the tissue properties of mass, stiffness, and viscosity, respectively. The coupling spring exemplified the tissue interactions. By numerically solving this chain model, the effects of mucosal loading on the phonation threshold pressure, phonation instability pressure, and energy distribution in a voice production system were studied. It was found that when mucosal loading is small, phonation threshold pressure increases with the damping constant R(r), the mass constant R(m), and the coupling constant R(mu) of mucosal loading but decreases with the stiffness constant R(k). Phonation instability pressure is also related to mucosal loading. It was found that phonation instability pressure increases with the coupling constant R(mu) but decreases with the stiffness constant R(k) of mucosal loading. Therefore, it was concluded that mucosal loading directly affects voice production.

  2. Effects of mucosal loading on vocal fold vibration

    NASA Astrophysics Data System (ADS)

    Tao, Chao; Jiang, Jack J.

    2009-06-01

    A chain model was proposed in this study to examine the effects of mucosal loading on vocal fold vibration. Mucosal loading was defined as the loading caused by the interaction between the vocal folds and the surrounding tissue. In the proposed model, the vocal folds and the surrounding tissue were represented by a series of oscillators connected by a coupling spring. The lumped masses, springs, and dampers of the oscillators modeled the tissue properties of mass, stiffness, and viscosity, respectively. The coupling spring exemplified the tissue interactions. By numerically solving this chain model, the effects of mucosal loading on the phonation threshold pressure, phonation instability pressure, and energy distribution in a voice production system were studied. It was found that when mucosal loading is small, phonation threshold pressure increases with the damping constant Rr, the mass constant Rm, and the coupling constant Rμ of mucosal loading but decreases with the stiffness constant Rk. Phonation instability pressure is also related to mucosal loading. It was found that phonation instability pressure increases with the coupling constant Rμ but decreases with the stiffness constant Rk of mucosal loading. Therefore, it was concluded that mucosal loading directly affects voice production.

  3. Modulating Phonation Through Alteration of Vocal Fold Medial Surface Contour

    PubMed Central

    Mau, Ted; Muhlestein, Joseph; Callahan, Sean; Chan, Roger W.

    2012-01-01

    Objectives 1. To test whether alteration of the vocal fold medial surface contour can improve phonation. 2. To demonstrate that implant material properties affect vibration even when implant is deep to the vocal fold lamina propria. Study Design Induced phonation of excised human larynges. Methods Thirteen larynges were harvested within 24 hours post-mortem. Phonation threshold pressure (PTP) and flow (PTF) were measured before and after vocal fold injections using either calcium hydroxylapatite (CaHA) or hyaluronic acid (HA). Small-volume injections (median 0.0625 mL) were targeted to the infero-medial aspect of the thyroarytenoid (TA) muscle. Implant locations were assessed histologically. Results The effect of implantation on PTP was material-dependent. CaHA tended to increase PTP, whereas HA tended to decrease PTP (Wilcoxon test P = 0.00013 for onset). In contrast, the effect of implantation on PTF was similar, with both materials tending to decrease PTF (P = 0.16 for onset). Histology confirmed implant presence in the inferior half of the vocal fold vertical thickness. Conclusions Taken together, these data suggested the implants may have altered the vocal fold medial surface contour, potentially resulting in a less convergent or more rectangular glottal geometry as a means to improve phonation. An implant with a closer viscoelastic match to vocal fold cover is desirable for this purpose, as material properties can affect vibration even when the implant is not placed within the lamina propria. This result is consistent with theoretical predictions and implies greater need for surgical precision in implant placement and care in material selection. PMID:22865592

  4. Effect of level difference between left and right vocal folds on phonation: Physical experiment and theoretical study.

    PubMed

    Tokuda, Isao T; Shimamura, Ryo

    2017-08-01

    As an alternative factor to produce asymmetry between left and right vocal folds, the present study focuses on level difference, which is defined as the distance between the upper surfaces of the bilateral vocal folds in the inferior-superior direction. Physical models of the vocal folds were utilized to study the effect of the level difference on the phonation threshold pressure. A vocal tract model was also attached to the vocal fold model. For two types of different models, experiments revealed that the phonation threshold pressure tended to increase as the level difference was extended. Based upon a small amplitude approximation of the vocal fold oscillations, a theoretical formula was derived for the phonation threshold pressure. This theory agrees with the experiments, especially when the phase difference between the left and right vocal folds is not extensive. Furthermore, an asymmetric two-mass model was simulated with a level difference to validate the experiments as well as the theory. The primary conclusion is that the level difference has a potential effect on voice production especially for patients with an extended level of vertical difference in the vocal folds, which might be taken into account for the diagnosis of voice disorders.

  5. Evidence for Adverse Phonatory Change Following an Inhaled Combination Treatment

    ERIC Educational Resources Information Center

    Erickson, Elizabeth; Sivasankar, Mahalakshmi

    2010-01-01

    Purpose: Voice problems are reported as a frequent side effect of inhaled combination (IC) treatments. The purpose of this experimental study was to investigate whether IC treatments are detrimental to phonation. We hypothesized that IC treatment would significantly increase phonation threshold pressure (PTP) and perceived phonatory effort (PPE),…

  6. Experimental and Theoretical Investigations of Phonation Threshold Pressure as a Function of Vocal Fold Elongation

    PubMed Central

    Tao, Chao; Regner, Michael F.; Zhang, Yu; Jiang, Jack J.

    2014-01-01

    Summary The relationship between the vocal fold elongation and the phonation threshold pressure (PTP) was experimentally and theoretically investigated. The PTP values of seventeen excised canine larynges with 0% to 15% bilateral vocal fold elongations in 5% elongation steps were measured using an excised larynx phonation system. It was found that twelve larynges exhibited a monotonic relationship between PTP and elongation; in these larynges, the 0% elongation condition had the lowest PTP. Five larynges exhibited a PTP minimum at 5% elongation. To provide a theoretical explanation of these phenomena, a two-mass model was modified to simulate vibration of the elongated vocal folds. Two pairs of longitudinal springs were used to represent the longitudinal elastin in the vocal folds. This model showed that when the vocal folds were elongated, the increased longitudinal tension would increase the PTP value and the increased vocal fold length would decrease the PTP value. The antagonistic effects contributed by these two factors were found to be able to cause either a monotonic or a non-monotonic relationship between PTP and elongation, which were consistent with experimental observations. Because PTP describes the ease of phonation, this study suggests that there may exist a nonzero optimal vocal fold elongation for the greatest ease for phonation in some larynges. PMID:25530744

  7. Lingering Effects of Straw Phonation Exercises on Aerodynamic, Electroglottographic, and Acoustic Parameters.

    PubMed

    Kang, Jing; Xue, Chao; Piotrowski, David; Gong, Ting; Zhang, Yi; Jiang, Jack J

    2018-06-01

    This study aimed to investigate the duration of straw phonation effects using aerodynamic, electroglottographic, and acoustic metrics. Twenty-four participants were recruited to perform both a 5-minute and a 10-minute straw phonation exercise. Upon completion of the exercises, phonation threshold pressure (PTP), mean airflow, contact quotient, fundamental frequency, jitter, shimmer, and noise-to-harmonics ratio were measured over a 20-minute time frame. Parameters were measured before the intervention (baseline), immediately after the intervention (m0), 5 minutes (m5), 10 minutes (m10), 15 minutes (m15), and 20 minutes (m20) after the intervention. PTP significantly decreased immediately after 5 minutes of straw phonation and returned to initial state within 5 minutes. PTP remained decreased over 5 minutes after 10 minutes of straw phonation. Mean airflow increased immediately after both 5 minutes and 10 minutes of straw phonations and remained improved for 20 minutes. No significant changes were obtained for contact quotient and acoustic parameters over the intervention period. The results extended our knowledge of proper clinical application of straw phonation regarding the duration of exercise. This study confirmed that 10 minutes of straw phonation lead to optimal and relatively continuous effects in PTP and mean airflow. Although straw phonation did show lingering effects in aerodynamics, repeated practices were recommended to obtain optimum and therapeutic effects. Copyright © 2018 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  8. Phonation threshold pressure predictions using viscoelastic properties up to 1,400 Hz of injectables intended for Reinke's space.

    PubMed

    Klemuk, Sarah A; Lu, Xiaoying; Hoffman, Henry T; Titze, Ingo R

    2010-05-01

    Viscoelastic properties of numerous vocal fold injectables have been reported but not at speaking frequencies. For materials intended for Reinke's space, ramifications of property values are of great concern because of their impact on ease of voice onset. Our objectives were: 1) to measure viscoelastic properties of a new nonresorbing carbomer and well-known vocal fold injectables at vocalization frequencies using established and new instrumentation, and 2) to predict phonation threshold pressures using a computer model with intended placement in Reinke's space. Rheology and phonation threshold pressure calculations. Injectables were evaluated with a traditional rotational rheometer and a new piezo-rotary vibrator. Using these data at vocalization frequencies, phonation threshold pressures (PTP) were calculated for each biomaterial, assuming a low dimensional model with supraglottic coupling and adjusted vocal fold length and thickness at each frequency. Results were normalized to a nominal PTP value. Viscoelastic data were acquired at vocalization frequencies as high as 363 to 1,400 Hz for six new carbomer hydrogels, Hylan B, and Extracel intended for vocal fold Reinke's space injection and for Cymetra (lateral injection). Reliability was confirmed with good data overlap when measuring with either rheometer. PTP predictions ranged from 0.001 to 16 times the nominal PTP value of 0.283 kPa. Accurate viscoelastic measurements of vocal fold injectables are now possible at physiologic frequencies. Hylan B, Extracel, and the new carbomer hydrogels should generate easy vocal onset and sustainable vocalization based on their rheologic properties if injected into Reinke's space. Applications may vary depending on desired longevity of implant. Laryngoscope, 2010.

  9. Describing different styles of singing: a comparison of a female singer's voice source in "Classical", "Pop", "Jazz" and "Blues".

    PubMed

    Thalén, M; Sundberg, J

    2001-01-01

    The voice is apparently used in quite different manners in different styles of singing. Some of these differences concern the voice source, which varies considerably with loudness, pitch, and mode of phonation. We attempt to describe voice source differences between Classical, Pop, Jazz and Blues styles of singing as produced in a triad melody pattern by a professional female singer in soft, middle and loud phonation. An expert panel was asked to identify these triads as examples of either Classical, Pop, Jazz or Blues. The voice source was analysed by inverse filtering. Subglottal pressure Ps, closed quotient QClosed, glottal compliance (ratio between the air volume contained in a voice pulse and Ps), and the level difference between the two lowest source spectrum partials were analysed in the styles and in four modes of phonation: breathy, flow, neutral, and pressed. The same expert panel rated the degree of pressedness in the entire material. Averages across pitch were calculated for each mode and style and related to their total range of variation in the subject. The glottogram data showed a high correlation with the ratings of pressedness. Based on these correlations a pressedness factor was computed from the glottogram data. A phonation map was constructed with the axes representing mean adduction factor and mean Ps, respectively. In this map Classical was similar to flow phonation, Pop and Jazz to neutral and flow phonation, and Blues to pressed phonation.

  10. A coupled sharp-interface immersed boundary-finite-element method for flow-structure interaction with application to human phonation.

    PubMed

    Zheng, X; Xue, Q; Mittal, R; Beilamowicz, S

    2010-11-01

    A new flow-structure interaction method is presented, which couples a sharp-interface immersed boundary method flow solver with a finite-element method based solid dynamics solver. The coupled method provides robust and high-fidelity solution for complex flow-structure interaction (FSI) problems such as those involving three-dimensional flow and viscoelastic solids. The FSI solver is used to simulate flow-induced vibrations of the vocal folds during phonation. Both two- and three-dimensional models have been examined and qualitative, as well as quantitative comparisons, have been made with established results in order to validate the solver. The solver is used to study the onset of phonation in a two-dimensional laryngeal model and the dynamics of the glottal jet in a three-dimensional model and results from these studies are also presented.

  11. Fluid Dynamics of Human Phonation and Speech

    NASA Astrophysics Data System (ADS)

    Mittal, Rajat; Erath, Byron D.; Plesniak, Michael W.

    2013-01-01

    This article presents a review of the fluid dynamics, flow-structure interactions, and acoustics associated with human phonation and speech. Our voice is produced through the process of phonation in the larynx, and an improved understanding of the underlying physics of this process is essential to advancing the treatment of voice disorders. Insights into the physics of phonation and speech can also contribute to improved vocal training and the development of new speech compression and synthesis schemes. This article introduces the key biomechanical features of the laryngeal physiology, reviews the basic principles of voice production, and summarizes the progress made over the past half-century in understanding the flow physics of phonation and speech. Laryngeal pathologies, which significantly enhance the complexity of phonatory dynamics, are discussed. After a thorough examination of the state of the art in computational modeling and experimental investigations of phonatory biomechanics, we present a synopsis of the pacing issues in this arena and an outlook for research in this fascinating subject.

  12. Patient-Specific Computational Modeling of Human Phonation

    NASA Astrophysics Data System (ADS)

    Xue, Qian; Zheng, Xudong; University of Maine Team

    2013-11-01

    Phonation is a common biological process resulted from the complex nonlinear coupling between glottal aerodynamics and vocal fold vibrations. In the past, the simplified symmetric straight geometric models were commonly employed for experimental and computational studies. The shape of larynx lumen and vocal folds are highly three-dimensional indeed and the complex realistic geometry produces profound impacts on both glottal flow and vocal fold vibrations. To elucidate the effect of geometric complexity on voice production and improve the fundamental understanding of human phonation, a full flow-structure interaction simulation is carried out on a patient-specific larynx model. To the best of our knowledge, this is the first patient-specific flow-structure interaction study of human phonation. The simulation results are well compared to the established human data. The effects of realistic geometry on glottal flow and vocal fold dynamics are investigated. It is found that both glottal flow and vocal fold dynamics present a high level of difference from the previous simplified model. This study also paved the important step toward the development of computer model for voice disease diagnosis and surgical planning. The project described was supported by Grant Number ROlDC007125 from the National Institute on Deafness and Other Communication Disorders (NIDCD).

  13. A Randomized Controlled Trial of Two Semi-Occluded Vocal Tract Voice Therapy Protocols

    ERIC Educational Resources Information Center

    Kapsner-Smith, Mara R.; Hunter, Eric J.; Kirkham, Kimberly; Cox, Karin; Titze, Ingo R.

    2015-01-01

    Purpose: Although there is a long history of use of semi-occluded vocal tract gestures in voice therapy, including phonation through thin tubes or straws, the efficacy of phonation through tubes has not been established. This study compares results from a therapy program on the basis of phonation through a flow-resistant tube (FRT) with Vocal…

  14. Dynamics of coherent flow structures of a pulsating unsteady glottal jet in human phonation.

    NASA Astrophysics Data System (ADS)

    Neubauer, Juergen; Miraghaie, Reza; Berry, David

    2004-11-01

    The primary sound source for human voice is oscillation of the vocal folds in the larynx. Phonation is the self-sustained oscillation of the viscoelastic vocal fold tissue driven by the air flow from the lung. It is due to the flow-induced Hopf instability of the biomechanical-aerodynamic system of vocal folds coupled to the aeroacoustic driving air flow. The aim of this study is to provide insight to the aero-acoustic part of the primary sound source of human voice. A physical rubber model of vocal folds with air flow conditions typical for human phonation was used. This model exhibits self-sustained oscillations similar to those in human phonation. The oscillating physical model can be regarded as a dynamic slit-like orifice that discharges a pulsating unsteady jet. A left-right flapping of the glottal jet axis was detected using hotwire anemometer measurements of the unsteady glottal jet. Flow visualization experiments revealed the detachment of the glottal jet from the physical model folds during the accelerating and decelerating phase of the jet pulsation. Roll-up of large-scale vortex rings as well as secondary vortex shedding in the form of Von Karman street due to shear layer instability were found downstream of the physical model.

  15. Differential Roles for the Thyroarytenoid and Lateral Cricoarytenoid Muscles in Phonation

    PubMed Central

    Chhetri, Dinesh K.; Neubauer, Juergen

    2015-01-01

    Objective Laryngeal adductor muscle dysfunction is common cause of voice disorders. Reconstitution of adductor muscle function is often the target of therapy, but the effects of these muscles on voice production remain to be fully understood. This study investigated the differential roles of thyroarytenoid (TA) and lateral cricoarytenoid (LCA) muscles on voice production. Study Design Basic science study using an in vivo canine model of phonation. Methods The TA and LCA muscle nerve branches were stimulated to obtain 7 graded levels of muscle activation, from threshold to maximal contraction. The effects of LCA activation alone, TA activation alone, and combined TA and LCA activation on phonation onset parameters were investigated. Phonatory posture, phonation onset type, fundamental frequency (F0), phonation onset pressure, and airflow were evaluated. Results LCA activation closed the posterior glottis but mid-membranous gap remained. TA activation closed the membranous glottis but posterior gap remained. Complete glottal closure was obtained only with combined TA and LCA activation. Phonation onset with LCAs alone was characterized by multiple modes (soft, aperiodic, periodic), while with TAs alone was abrupt and periodic but had significant baseline noise. Combined muscle activation led to elimination of baseline noise with stable abrupt periodic onset of phonation. Combined muscle activation was also necessary for F0 variation. LCA assisted the TA in increasing subglottal pressure while concurrently reducing phonation onset airflow. Conclusion TA is necessary for F0 variation, stable onset phonation, and increased subglottal pressure but needs LCA for optimal effectiveness and to reduce airflow requirements with increased activation. PMID:26198167

  16. Voice Function Differences Following Resting Breathing vs. Submaximal Exercise

    PubMed Central

    Sandage, Mary J.; Connor, Nadine P.; Pascoe, David D.

    2013-01-01

    Objectives/Hypothesis There is little known about how physical exercise may alter physiological parameters of voice production. In this investigation, vocal function and upper airway temperature were examined following a bout of submaximal exercise and compared with a resting breathing condition. It was hypothesized that phonation threshold pressure and perceived phonatory effort would increase, and pharyngeal temperature would decrease following an exercise bout. Study Design Using a within-participant repeated measures design, 18 consented participants (9 men, 9 women) completed the study. Methods A 20-minute equilibration task was immediately followed by 8 minutes of submaximal exercise on a stationary bike in a thermally neutral environment (25°C/40% RH). At the end of the equilibration trial and the exercise trial measures were taken in the following order: pharyngeal temperature, phonation threshold pressure, and perceived phonatory effort. Data were analyzed using paired t-tests with significance set at α<0.05. Results Significantly increased phonation threshold pressure and perceived phonatory effort and significantly decreased pharyngeal temperature (1.9°C) were found, supporting the initial hypotheses. Conclusions Findings from this investigation support the widely held belief that voice use associated with physical activity requires additional laryngeal effort and closure forces. The effect of the temperature reduction in the upper airway on voice function requires further study. PMID:23849683

  17. Glottal Adduction and Subglottal Pressure in Singing.

    PubMed

    Herbst, Christian T; Hess, Markus; Müller, Frank; Švec, Jan G; Sundberg, Johan

    2015-07-01

    Previous research suggests that independent variation of vocal loudness and glottal configuration (type and degree of vocal fold adduction) does not occur in untrained speech production. This study investigated whether these factors can be varied independently in trained singing and how subglottal pressure is related to average glottal airflow, voice source properties, and sound level under these conditions. A classically trained baritone produced sustained phonations on the endoscopic vowel [i:] at pitch D4 (approximately 294 Hz), exclusively varying either (a) vocal register; (b) phonation type (from "breathy" to "pressed" via cartilaginous adduction); or (c) vocal loudness, while keeping the others constant. Phonation was documented by simultaneous recording of videokymographic, electroglottographic, airflow and voice source data, and by percutaneous measurement of relative subglottal pressure. Register shifts were clearly marked in the electroglottographic wavegram display. Compared with chest register, falsetto was produced with greater pulse amplitude of the glottal flow, H1-H2, mean airflow, and with lower maximum flow declination rate (MFDR), subglottal pressure, and sound pressure. Shifts of phonation type (breathy/flow/neutral/pressed) induced comparable systematic changes. Increase of vocal loudness resulted in increased subglottal pressure, average flow, sound pressure, MFDR, glottal flow pulse amplitude, and H1-H2. When changing either vocal register or phonation type, subglottal pressure and mean airflow showed an inverse relationship, that is, variation of glottal flow resistance. The direct relation between subglottal pressure and airflow when varying only vocal loudness demonstrated independent control of vocal loudness and glottal configuration. Achieving such independent control of phonatory control parameters would be an important target in vocal pedagogy and in voice therapy. Copyright © 2015 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  18. Nonlinear Analyses of Elicited Modal, Raised, and Pressed Rabbit Phonation

    PubMed Central

    Awan, Shaheen N.; Novaleski, Carolyn K.; Rousseau, Bernard

    2014-01-01

    Objectives/Hypothesis The purpose of this study was to use nonlinear dynamic analysis methods such as phase space portraits and correlation dimension (D2) as well as descriptive spectrographic analyses to characterize acoustic signals produced during evoked rabbit phonation. Methods Seventeen New Zealand white breeder rabbits were used to perform the study. A Grass S-88 stimulator (SA Instrumentation, Encinitas, CA) and constant current isolation unit (Grass Telefactor, model PSIU6; West Warwick, RI) were used to provide electrical stimulation to laryngeal musculature, and transglottal airflow rate and stimulation current (mA) were manipulated to elicit modal, raised intensity, and pressed phonations. Central 1 second portions of the most stable portion of the acoustic waveform for modal, raised intensity, and pressed phonations were edited, and then analyzed via phase space portraits, Poincaré sections, and the estimation of the correlation dimension (D2). In an attempt to limit the effects of the highly variable and nonstationary characteristics of some of the signals being analyzed, D2 analysis was also performed on the most stable central 200 ms portion of the acoustic waveform. Descriptive analysis of each phonation was also conducted using sound spectrograms. Results Results showed that the complexity of phonation and the subsequent acoustic waveform is increased as transglottal airflow rate and degree of glottal adduction is manipulated in the evoked rabbit phonation model. In particular, phonatory complexity, as quantified via correlation dimension analyses and demonstrated via spectrographic characteristics, increases from “modal” (i.e., phonation elicited at just above the phonation threshold pressure) to raised intensity (phonation elicited by increasing transglottal airflow rate) to pressed (phonation elicited by increasing the stimulation current delivered to the larynx). Variations in a single dynamic dimension (airflow rate or adductory force) resulted in significantly increased productions of nonlinear phenomenon, including bifurcations from periodicity to regions of subharmonic content, F0 and harmonic jumps, and evidence of periodicity within aperiodic regions (“chaos”). Conclusions The evoked rabbit phonation model described in this study allows for the elicitation of various types of phonations under controlled conditions and therefore, has the potential to provide insight regarding important variables that may elicit examples of nonlinear phenomena such as subharmonics and deterministic chaos. PMID:24836360

  19. Regulation of glottal closure and airflow in a three-dimensional phonation model: Implications for vocal intensity control

    PubMed Central

    Zhang, Zhaoyan

    2015-01-01

    Maintaining a small glottal opening across a large range of voice conditions is critical to normal voice production. This study investigated the effectiveness of vocal fold approximation and stiffening in regulating glottal opening and airflow during phonation, using a three-dimensional numerical model of phonation. The results showed that with increasing subglottal pressure the vocal folds were gradually pushed open, leading to increased mean glottal opening and flow rate. A small glottal opening and a mean glottal flow rate typical of human phonation can be maintained against increasing subglottal pressure by proportionally increasing the degree of vocal fold approximation for low to medium subglottal pressures and vocal fold stiffening at high subglottal pressures. Although sound intensity was primarily determined by the subglottal pressure, the results suggest that, to maintain small glottal opening as the sound intensity increases, one has to simultaneously tighten vocal fold approximation and/or stiffen the vocal folds, resulting in increased glottal resistance, vocal efficiency, and fundamental frequency. PMID:25698022

  20. Vocal-fold collision mass as a differentiator between registers in the low-pitch range.

    PubMed

    Vilkman, E; Alku, P; Laukkanen, A M

    1995-03-01

    Register shift between the chest and falsetto register is generally studied in the higher-than-speaking pitch range. However, a similar difference can also be produced at speaking pitch level. The shift from breathy "falsetto" phonation to normal chest voice phonation was studied in normal female (pitch range 170-180 Hz) and male (pitch range 94-110 Hz) subjects. The phonations gliding from falsetto to normal chest voice were analyzed using iterative adaptive inverse filtering and electroglottography. Both trained and untrained, as well as female and male subjects, were able to produce an abrupt register shift from soft falsetto to soft chest register phonation. The differences between male and female speakers in the glottal flow waveforms were smaller than expected. The register shift is interpreted in terms of a "critical mass" concept of chest register phonation.

  1. Shear properties of vocal fold mucosal tissues and their effect on vocal fold oscillation

    NASA Astrophysics Data System (ADS)

    Chan, Roger Wai Kai

    Viscoelastic shear properties of vocal fold mucosal tissues and phonosurgical biomaterials were measured with a parallel-plate rotational rheometer. Elastic, viscous and damping properties were quantified as a function of frequency (0.01 Hz to 15 Hz) for human vocal fold mucosal tissues (N = 15), implantable biomaterials commonly used in the treatment of vocal fold paralysis (Teflon, gelatin, and collagen) (the non-mucosal group), and biomaterials currently or potentially useful in the treatment of vocal fold mucosal defects (adipose tissue or fat, hyaluronic acid, and fibronectin) (the mucosal group). It was found that intersubject differences as large as an order of magnitude were often observed for the shear properties of vocal fold mucosal tissues, part of which may be age- and gender-related. Shear properties of the non-mucosal group biomaterials were often much higher than those of the mucosal group biomaterials, which were relatively close to the shear properties of mucosal tissues. Viscoelastic and rheological modeling showed that shear properties of human vocal fold mucosa may be described by a quasi-linear viscoelastic theory and a statistical network theory, based upon which extrapolations to audio frequencies were possible. A theory of small-amplitude vocal fold oscillation was revisited to describe the effects of tissue shear properties on vocal fold oscillation and phonation threshold pressure, a measure of the 'ease' of phonation and an objective indication of vocal function. It was found that phonation threshold pressure is directly related to the viscous shear modulus or the 'effective damping modulus', a concept proposed to quantify the effective amount of damping in vocal fold oscillation. The mucosal group biomaterials were incorporated into the artificial vocal fold mucosa of a physical model in order to empirically assess their effects on phonation threshold pressure. Results showed that higher threshold pressures were consistently observed for higher concentrations of hyaluronic acid and for hyaluronic acid mixed with fibronectin, in correlation with their differences in viscous shear modulus and effective damping modulus. Implications for phonosurgery were discussed in terms of the choice of optimal biomaterials for the surgical management of vocal fold mucosal defects and lamina propria deficiencies.

  2. Dependence of phonation threshold pressure on vocal tract acoustics and vocal fold tissue mechanics.

    PubMed

    Chan, Roger W; Titze, Ingo R

    2006-04-01

    Analytical and computer simulation studies have shown that the acoustic impedance of the vocal tract as well as the viscoelastic properties of vocal fold tissues are critical for determining the dynamics and the energy transfer mechanism of vocal fold oscillation. In the present study, a linear, small-amplitude oscillation theory was revised by taking into account the propagation of a mucosal wave and the inertive reactance (inertance) of the supraglottal vocal tract as the major energy transfer mechanisms for flow-induced self-oscillation of the vocal fold. Specifically, analytical results predicted that phonation threshold pressure (Pth) increases with the viscous shear properties of the vocal fold, but decreases with vocal tract inertance. This theory was empirically tested using a physical model of the larynx, where biological materials (fat, hyaluronic acid, and fibronectin) were implanted into the vocal fold cover to investigate the effect of vocal fold tissue viscoelasticity on Pth. A uniform-tube supraglottal vocal tract was also introduced to examine the effect of vocal tract inertance on Pth. Results showed that Pth decreased with the inertive impedance of the vocal tract and increased with the viscous shear modulus (G") or dynamic viscosity (eta') of the vocal fold cover, consistent with theoretical predictions. These findings supported the potential biomechanical benefits of hyaluronic acid as a surgical bioimplant for repairing voice disorders involving the superficial layer of the lamina propria, such as scarring, sulcus vocalis, atrophy, and Reinke's edema.

  3. Comparing the Exposure-Response Relationships of Physiological and Traditional Vocal Warm-ups on Aerodynamic and Acoustic Parameters in Untrained Singers.

    PubMed

    Kang, Jing; Xue, Chao; Chou, Adriana; Scholp, Austin; Gong, Ting; Zhang, Yi; Chen, Zhen; Jiang, Jack J

    2018-02-05

    The aim of this study was to quantify the effects of traditional and physiological warm-up exercises and to determine the optimal duration of these methods using acoustic and aerodynamic metrics. Twenty-six subjects were recruited to participate in both straw phonation exercises (physiological vocal warm-up) and traditional singing exercises (traditional vocal warm-up) for 20 minutes each, 24 hours apart. Phonation threshold pressure (PTP), fundamental frequency, jitter, shimmer, and noise-to-harmonics ratio were measured before the intervention (m0), as well as after 5 minutes (m5), 10 minutes (m10), 15 minutes (m15), and 20 minutes (m20) of intervention. PTP decreased significantly after straw phonation and reached a minimum value at 10 minutes (P < 0.001) and remained stable in traditional singing exercises. There were significant differences in fundamental frequency and shimmer from m0 to m15 and m20 in the traditional singing group (P = 0.001, P = 0.001, P = 0.001, and P = 0.002, respectively). No significant changes in acoustic parameters were observed after straw phonation. Both straw phonation exercises and traditional singing exercises are effective for voice warm-up. Straw phonation improves the subjects' fatigue resistance and vocal economy, resulting in a reduced PTP, whereas traditional singing exercises focus on technical singing skills, leading to an improvement of acoustic variables. Copyright © 2018 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  4. Contact Quotient of Female Singers Singing Four Pitches for Five Vowels in Normal and Pressed Phonations.

    PubMed

    Ong Tan, Kendrich Graemer

    2017-09-01

    The present study aimed to investigate the contact quotient (CQ) values of breathy, normal, and pressed phonation types in four different sections of the female singing range. Electroglottography (EGG) and acoustic signals were recorded from 10 female singing teachers. Five vowels were sung for 1-3 seconds each, in three phonation types-normal, breathy, and pressed, in four pitches representing registration change points in the singing range. CQ values were automatically generated from the EGG signal using VoceVista at 35% threshold level. Sound pressure levels were checked in Praat. Unianova and correlations were performed using an SPSS program. CQ values of female participants in the study yielded ranges of 0.25-0.62 in normal and 0.34-0.73 in pressed. Normal and pressed CQ differed significantly from each other at P < 0.00. Breathy samples were not viable for analysis. A concentration of CQ values from 0.5 to 0.6 of both pressed low and pressed break samples was noted, but CQ values across the pitch range showed no significant trend. Normal and pressed phonation CQ values beyond the speaking pitch varied among the subjects. Pressed phonation CQ values were mostly higher, but the values were only relative to the corresponding normal phonation on the same pitch. Other measurements may be more suitable for measuring vocal fold impact stress in higher frequencies, thus, distinguishing normal from pressed singing. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  5. Collision and phonation threshold pressures before and after loud, prolonged vocalization in trained and untrained voices.

    PubMed

    Enflo, Laura; Sundberg, Johan; McAllister, Anita

    2013-09-01

    The phonation threshold pressure (PTP) is defined as the lowest subglottal pressure needed for obtaining and sustaining vocal fold oscillation. It has been found to increase during vocal fatigue. In the present study, PTP is measured together with the threshold pressure needed for vocal fold collision; henceforth, the collision threshold pressure (CTP). PTP and CTP are compared before and after loud, prolonged vocalization in singer and nonsinger voices. Ten subjects repeated the vowel sequence /a, e, i, o, u/ at a Sound Pressure Level of at least 80 dB at 0.3 m for 20 minutes. Audio and electroglottography signals were recorded before and after this exercise. At the same time, oral pressure was registered while the subjects produced a diminuendo repeating the syllable /pa:/, thus acquiring an approximate of the subglottal pressure. CTP and PTP increased significantly after the vocal loading in the nonsinger subjects. On the other hand, singers reported no substantial effect of the exercise, and most singers had a mean after-to-before ratio close to 1 for both CTP and PTP. Copyright © 2013 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  6. [Acoustic and aerodynamic characteristics of the oesophageal voice].

    PubMed

    Vázquez de la Iglesia, F; Fernández González, S

    2005-12-01

    The aim of the study is to determine the physiology and pathophisiology of esophageal voice according to objective aerodynamic and acoustic parameters (quantitative and qualitative parameters). Our subjects were comprised of 33 laryngectomized patients (all male) that underwent aerodynamic, acoustic and perceptual protocol. There is a statistical association between acoustic and aerodynamic qualitative parameters (phonation flow chart type, sound spectrum, perceptual analysis) among quantitative parameters (neoglotic pressure, phonation flow, phonation time, fundamental frequency, maximum intensity sound level, speech rate). Nevertheles, not always such observations bring practical resources to clinical practice. We consider that the facts studied may enable us to add, pragmatically, new resources to the more effective vocal rehabilitation to these patients. The physiology of esophageal voice is well understood by the method we have applied, also seeking for rehabilitation, improving oral communication skills in the laryngectomee population.

  7. Unsteady flow motions in the supraglottal region during phonation

    NASA Astrophysics Data System (ADS)

    Luo, Haoxiang; Dai, Hu

    2008-11-01

    The highly unsteady flow motions in the larynx are not only responsible for producing the fundamental frequency tone in phonation, but also have a significant contribution to the broadband noise in the human voice. In this work, the laryngeal flow is modeled either as an incompressible pulsatile jet confined in a two-dimensional channel, or a pressure-driven flow modulated by a pair of viscoelastic vocal folds through the flow--structure interaction. The flow in the supraglottal region is found to be dominated by large-scale vortices whose unsteady motions significantly deflect the glottal jet. In the flow--structure interaction, a hybrid model based on the immersed-boundary method is developed to simulate the flow-induced vocal fold vibration, which involves a three-dimensional vocal fold prototype and a two-dimensional viscous flow. Both the flow behavior and the vibratory characteristics of the vocal folds will be presented.

  8. Regional cerebral blood flow for singers and nonsingers while speaking, singing, and humming a rote passage

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Formby, C.; Thomas, R.G.; Halsey, J.H. Jr.

    1989-05-01

    Two groups of singers (n = 12,13) and a group of nonsingers (n = 12) each produced the national anthem by (1) speaking and (2) singing the words and by (3) humming the melody. Regional cerebral blood flow (rCBF) was measured at rest and during each phonation task from seven areas in each hemisphere by the {sup 133}Xe-inhalation method. Intrahemisphere, interhemisphere, and global rCBF were generally similar across phonation tasks and did not yield appreciable differences among the nonsingers and the singers.

  9. Regional cerebral blood flow for singers and nonsingers while speaking, singing, and humming a rote passage.

    PubMed

    Formby, C; Thomas, R G; Halsey, J H

    1989-05-01

    Two groups of singers (n = 12,13) and a group of nonsingers (n = 12) each produced the national anthem by (1) speaking and (2) singing the words and by (3) humming the melody. Regional cerebral blood flow (rCBF) was measured at rest and during each phonation task from seven areas in each hemisphere by the 133Xe-inhalation method. Intrahemisphere, interhemisphere, and global rCBF were generally similar across phonation tasks and did not yield appreciable differences among the nonsingers and the singers.

  10. Simulations of acoustic waves in channels and phonation in glottal ducts

    NASA Astrophysics Data System (ADS)

    Yang, Jubiao; Krane, Michael; Zhang, Lucy

    2014-11-01

    Numerical simulations of acoustic wave propagation were performed by solving compressible Navier-Stokes equations using finite element method. To avoid numerical contamination of acoustic field induced by non-physical reflections at computational boundaries, a Perfectly Matched Layer (PML) scheme was implemented to attenuate the acoustic waves and their reflections near these boundaries. The acoustic simulation was further combined with the simulation of interaction of vocal fold vibration and glottal flow, using our fully-coupled Immersed Finite Element Method (IFEM) approach, to study phonation in the glottal channel. In order to decouple the aeroelastic and aeroacoustic aspects of phonation, the airway duct used has a uniform cross section with PML properly applied. The dynamics of phonation were then studied by computing the terms of the equations of motion for a control volume comprised of the fluid in the vicinity of the vocal folds. It is shown that the principal dynamics is comprised of the near cancellation of the pressure force driving the flow through the glottis, and the aerodynamic drag on the vocal folds. Aeroacoustic source strengths are also presented, estimated from integral quantities computed in the source region, as well as from the radiated acoustic field.

  11. The influence of water resistance therapy on vocal fold vibration: a high-speed digital imaging study.

    PubMed

    Guzman, Marco; Laukkanen, Anne-Maria; Traser, Louisa; Geneid, Ahmed; Richter, Bernhard; Muñoz, Daniel; Echternach, Matthias

    2017-10-01

    This study investigated the influence of tube phonation into water on vocal fold vibration. Eight participants were analyzed via high-speed digital imaging while phonating into a silicon tube with the free end submerged into water. Two test sequences were studied: (1) phonation pre, during, and post tube submerged 5 cm into water; and (2) phonation into tube submerged 5 cm, 10 cm, and 18 cm into water. Several glottal area parameters were calculated using phonovibrograms. The results showed individual differences. However, certain trends were possible to identify based on similar results found for the majority of participants. Amplitude-to-length ratio, harmonic-to-noise ratio, and spectral flatness (derived from glottal area) decreased for all tube immersion depths, while glottal closing quotient increased for 10 cm immersion and contact quotient for 18 cm immersion. Closed quotient decreased during phonation into the tube at 5 cm depth, and jitter decreased during and after it. Results suggest that the depth of tube submersion appears to have an effect on phonation. Shallow immersion seems to promote smoother and more stable phonation, while deeper immersion may involve increased respiratory and glottal effort to compensate for the increased supraglottal resistance. This disparity, which is dependent upon the degree of flow resistance, should be considered when choosing treatment exercises for patients with various diagnoses, namely hyperfunctional or hypofunctional dysphonia.

  12. Phonation threshold pressure across the pitch range: preliminary test of a model.

    PubMed

    Solomon, Nancy Pearl; Ramanathan, Pradeep; Makashay, Matthew J

    2007-09-01

    This study sought to examine the specific relationship between phonation threshold pressure (PTP) and voice fundamental frequency (F(0)) across the pitch range. A published theoretical model of this relationship described a quadratic equation, with PTP increasing exponentially with F(0). Prospective data from eight adults with normal, untrained voices were collected. Subjects produced their quietest phonation at 10 randomly ordered pitches from 5% to 95% of their semitone pitch range at 10% intervals. Analysis included curve fitting for individual and group data, as well as comparisons to the previous model. The group data fit a quadratic function similar to that proposed previously, but the specific quadratic coefficient and constant values differed. Four of the individual subjects' data were best fit by quartic functions, two by quadratic functions, and one by a linear function. This preliminary study indicates that PTP may be minimal at a "comfortable" pitch rather than the lowest pitch tested, and that, for some individuals, PTP may be slightly elevated during the passaggio between modal and falsetto vocal registers. These data support the general form of the theoretical PTP-F(0) function for these speakers, and indicate the possibility of potential refinements to the model. Future studies with larger groups of male and female subjects across a wider age range may eventually reveal the specific nature of the function.

  13. The ALE Discontinuous Galerkin Method for the Simulatio of Air Flow Through Pulsating Human Vocal Folds

    NASA Astrophysics Data System (ADS)

    Feistauer, Miloslav; Kučera, Václav; Prokopová, Jaroslav; Horáček, Jaromír

    2010-09-01

    The aim of this work is the simulation of viscous compressible flows in human vocal folds during phonation. The computational domain is a bounded subset of IR2, whose geometry mimics the shape of the human larynx. During phonation, parts of the solid impermeable walls are moving in a prescribed manner, thus simulating the opening and closing of the vocal chords. As the governing equations we take the compressible Navier-Stokes equations in ALE form. Space semidiscretization is carried out by the discontinuous Galerkin method combined with a linearized semi-implicit approach. Numerical experiments are performed with the resulting scheme.

  14. Power flow in normal human voice production

    NASA Astrophysics Data System (ADS)

    Krane, Michael

    2016-11-01

    The principal mechanisms of energy utilization in voicing are quantified using a simplified model, in order to better define voice efficiency. A control volume analysis of energy utilization in phonation is presented to identify the energy transfer mechanisms in terms of their function. Conversion of subglottal airstream potential energy into useful work done (vocal fold vibration, flow work, sound radiation), and into heat (sound radiation absorbed by the lungs, glottal jet dissipation) are described. An approximate numerical model is used to compute the contributions of each of these mechanisms, as a function of subglottal pressure, for normal phonation. Acknowledge support of NIH Grant 2R01DC005642-10A1.

  15. Oral Breathing Challenge in Participants with Vocal Attrition

    ERIC Educational Resources Information Center

    Sivasankar, Mahalakshmi; Fisher, Kimberly V.

    2003-01-01

    Vocal folds undergo osmotic challenge by mouth breathing during singing, exercising, and loud speaking. Just 15 min of obligatory oral breathing, to dry the vocal folds, increases phonation threshold pressure (P[subscript th]) and expiratory vocal effort in healthy speakers (M. Sivasankar & K. Fisher, 2002). We questioned whether oral breathing is…

  16. The Effects of Three Nebulized Osmotic Agents in the Dry Larynx

    ERIC Educational Resources Information Center

    Tanner, Kristine; Roy, Nelson; Merrill, Ray M.; Elstad, Mark

    2007-01-01

    Purpose: This investigation examined the effects of nebulized hypertonic saline, isotonic saline (IS), and sterile (hypotonic) water on phonation threshold pressure (PTP) and self-perceived phonatory effort (PPE) following a surface laryngeal dehydration challenge. Method: In a double-blind, randomized experimental trial, 60 vocally healthy women…

  17. The effect of stretch-and-flow voice therapy on measures of vocal function and handicap.

    PubMed

    Watts, Christopher R; Diviney, Shelby S; Hamilton, Amy; Toles, Laura; Childs, Lesley; Mau, Ted

    2015-03-01

    To investigate the efficacy of stretch-and-flow voice therapy as a primary physiological treatment for patients with hyperfunctional voice disorders. Prospective case series. Participants with a diagnosis of primary muscle tension dysphonia or phonotraumatic lesions due to hyperfunctional vocal behaviors were included. Participants received stretch-and-flow voice therapy structured once weekly for 6 weeks. Outcome variables consisted of two physiologic measures (s/z ratio and maximum phonation time), an acoustic measure (cepstral peak prominence [CPP]), and a measure of vocal handicap (voice handicap index [VHI]). All measures were obtained at baseline before treatment and within 2 weeks posttreatment. The s/z ratio, maximum phonation time, sentence CPP, and VHI showed statistically significant (P < 0.05) improvement through therapy. Effect sizes reflecting the magnitude of change were large for s/z ratio and VHI (d = 1.25 and 1.96 respectively), and moderate for maximum phonation time and sentence CPP (d = 0.79 and 0.74, respectively). This study provides supporting evidence for preliminary efficacy of stretch-and-flow voice therapy in a small sample of patients. The treatment effect was large or moderate for multiple outcome measures. The data provide justification for larger, controlled clinical trials on the application of stretch-and-flow voice therapy in the treatment of hyperfunctional voice disorders. Copyright © 2015 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  18. Involuntary expiratory phonation as a dose-related consequence of L-dopa therapy in a patient with Parkinson's disease.

    PubMed

    Ishii, Kosuke; Kumada, Masanobu; Ueki, Akira; Yamamoto, Masanori; Hirose, Hajime

    2003-12-01

    We report a case of involuntary phonation caused by abnormal vocal cord movements during expiration in a patient with Parkinson's disease. A 60-year-old woman had been treated for parkinsonism at the outpatient clinic of the Department of Neurology since August 1999. She began to groan involuntarily in the daytime in September 2001. She could not eat well while groaning. Stridor was not noted during sleep at night. Endoscopic examination of the larynx revealed insufficient abduction of the bilateral vocal cords, although the glottis was not so small as to cause stridor during inspiration. During expiration, however, the vocal cords adducted, resulting in the involuntary production of voice. Electromyography showed an increase in the activity of the thyroarytenoid and lateral cricoarytenoid muscles. This muscle activity was further enhanced during inspiration. The involuntary phonation disappeared when the patient's dose of L-dopa was decreased, although she had a decrease in her systemic mobility as well. When the dose of L-dopa was increased to the therapeutic level, involuntary phonation recurred, and her voluntary systemic activity improved. In the present case, it was considered that excessive dopaminergic denervation occurred in the nerve innervating the laryngeal adductors. Involuntary voice appeared to be produced by hypertonus of the laryngeal adductors because of a lowering in the threshold level for L-dopa, even though the drug was administered at the usual dose.

  19. Nebulized Isotonic Saline versus Water following a Laryngeal Desiccation Challenge in Classically Trained Sopranos

    ERIC Educational Resources Information Center

    Tanner, Kristine; Roy, Nelson; Merrill, Ray M.; Muntz, Faye; Houtz, Daniel R.; Sauder, Cara; Elstad, Mark; Wright-Costa, Julie

    2010-01-01

    Purpose: To examine the effects of nebulized isotonic saline (IS) versus sterile water (SW) on self-perceived phonatory effort (PPE) and phonation threshold pressure (PTP) following a surface laryngeal dehydration challenge in classically trained sopranos. Method: In a double-blind, within-subject crossover design, 34 sopranos breathed dry air…

  20. Vocal Function and Upper Airway Thermoregulation in Five Different Environmental Conditions

    ERIC Educational Resources Information Center

    Sandage, Mary J.; Connor, Nadine P.; Pascoe, David D.

    2014-01-01

    Purpose: Phonation threshold pressure and perceived phonatory effort were hypothesized to increase and upper airway temperature to decrease following exposure to cold and/or dry air. Greater changes were expected with mouth versus nose breathing. Method: In a within-participant repeated measures design, 15 consented participants (7 men, 8 women)…

  1. A Flow Perfusion Bioreactor System for Vocal Fold Tissue Engineering Applications

    PubMed Central

    Heris, Hossein K.; Thomson, Scott L.; Taher, Rani; Kazemirad, Siavash; Sheibani, Sara; Li-Jessen, Nicole Y.K.; Vali, Hojatollah; Mongeau, Luc

    2016-01-01

    The human vocal folds (VFs) undergo complex biomechanical stimulation during phonation. The aim of the present study was to develop and validate a phono-mimetic VF flow perfusion bioreactor, which mimics the mechanical microenvironment of the human VFs in vitro. The bioreactor uses airflow-induced self-oscillations, which have been shown to produce mechanical loading and contact forces that are representative of human phonation. The bioreactor consisted of two synthetic VF replicas within a silicone body. A cell-scaffold mixture (CSM) consisting of human VF fibroblasts, hyaluronic acid, gelatin, and a polyethylene glycol cross-linker was injected into cavities within the replicas. Cell culture medium (CCM) was perfused through the scaffold by using a customized secondary flow loop. After the injection, the bioreactor was operated with no stimulation over a 3-day period to allow for cell adaptation. Phonation was subsequently induced by using a variable speed centrifugal blower for 2 h each day over a period of 4 days. A similar bioreactor without biomechanical stimulation was used as the nonphonatory control. The CSM was harvested from both VF replicas 7 days after the injection. The results confirmed that the phono-mimetic bioreactor supports cell viability and extracellular matrix proteins synthesis, as expected. Many scaffold materials were found to degrade because of challenges from phonation-induced biomechanical stimulation as well as due to biochemical reactions with the CCM. The bioreactor concept enables future investigations of the effects of different phonatory characteristics, that is, voice regimes, on the behavior of the human VF cells. It will also help study the long-term functional outcomes of the VF-specific biomaterials before animal and clinical studies. PMID:27537192

  2. A Flow Perfusion Bioreactor System for Vocal Fold Tissue Engineering Applications.

    PubMed

    Latifi, Neda; Heris, Hossein K; Thomson, Scott L; Taher, Rani; Kazemirad, Siavash; Sheibani, Sara; Li-Jessen, Nicole Y K; Vali, Hojatollah; Mongeau, Luc

    2016-09-01

    The human vocal folds (VFs) undergo complex biomechanical stimulation during phonation. The aim of the present study was to develop and validate a phono-mimetic VF flow perfusion bioreactor, which mimics the mechanical microenvironment of the human VFs in vitro. The bioreactor uses airflow-induced self-oscillations, which have been shown to produce mechanical loading and contact forces that are representative of human phonation. The bioreactor consisted of two synthetic VF replicas within a silicone body. A cell-scaffold mixture (CSM) consisting of human VF fibroblasts, hyaluronic acid, gelatin, and a polyethylene glycol cross-linker was injected into cavities within the replicas. Cell culture medium (CCM) was perfused through the scaffold by using a customized secondary flow loop. After the injection, the bioreactor was operated with no stimulation over a 3-day period to allow for cell adaptation. Phonation was subsequently induced by using a variable speed centrifugal blower for 2 h each day over a period of 4 days. A similar bioreactor without biomechanical stimulation was used as the nonphonatory control. The CSM was harvested from both VF replicas 7 days after the injection. The results confirmed that the phono-mimetic bioreactor supports cell viability and extracellular matrix proteins synthesis, as expected. Many scaffold materials were found to degrade because of challenges from phonation-induced biomechanical stimulation as well as due to biochemical reactions with the CCM. The bioreactor concept enables future investigations of the effects of different phonatory characteristics, that is, voice regimes, on the behavior of the human VF cells. It will also help study the long-term functional outcomes of the VF-specific biomaterials before animal and clinical studies.

  3. The Effect of Hydration on Voice Quality in Adults: A Systematic Review.

    PubMed

    Alves, Maxine; Krüger, Esedra; Pillay, Bhavani; van Lierde, Kristiane; van der Linde, Jeannie

    2017-11-06

    We aimed to critically appraise scientific, peer-reviewed articles, published in the past 10 years on the effects of hydration on voice quality in adults. This is a systematic review. Five databases were searched using the key words "vocal fold hydration", "voice quality", "vocal fold dehydration", and "hygienic voice therapy". The Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines were followed. The included studies were scored based on American Speech-Language-Hearing Association's levels of evidence and quality indicators, as well as the Cochrane Collaboration's risk of bias tool. Systemic dehydration as a result of fasting and not ingesting fluids significantly negatively affected the parameters of noise-to-harmonics ratio (NHR), shimmer, jitter, frequency, and the s/z ratio. Water ingestion led to significant improvements in shimmer, jitter, frequency, and maximum phonation time values. Caffeine intake does not appear to negatively affect voice production. Laryngeal desiccation challenges by oral breathing led to surface dehydration which negatively affected jitter, shimmer, NHR, phonation threshold pressure, and perceived phonatory effort. Steam inhalation significantly improved NHR, shimmer, and jitter. Only nebulization of isotonic solution decreased phonation threshold pressure and showed some indication of a potential positive effect of nebulization substances. Treatments in high humidity environments prove to be effective and adaptations of low humidity environments should be encouraged. Recent literature regarding vocal hydration is high quality evidence. Systemic hydration is the easiest and most cost-effective solution to improve voice quality. Recent evidence therefore supports the inclusion of hydration in a vocal hygiene program. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  4. Asymmetric vibration in a two-layer vocal fold model with left-right stiffness asymmetry: Experiment and simulation

    PubMed Central

    Zhang, Zhaoyan; Hieu Luu, Trung

    2012-01-01

    Vibration characteristics of a self-oscillating two-layer vocal fold model with left-right asymmetry in body-layer stiffness were experimentally and numerically investigated. Two regimes of distinct vibratory pattern were identified as a function of left-right stiffness mismatch. In the first regime with extremely large left-right stiffness mismatch, phonation onset resulted from an eigenmode synchronization process that involved only eigenmodes of the soft fold. Vocal fold vibration in this regime was dominated by a large-amplitude vibration of the soft fold, and phonation frequency was determined by the properties of the soft fold alone. The stiff fold was only enslaved to vibrate at a much reduced amplitude. In the second regime with small left-right stiffness mismatch, eigenmodes of both folds actively participated in the eigenmode synchronization process. The two folds vibrated with comparable amplitude, but the stiff fold consistently led the soft fold in phase for all conditions. A qualitatively good agreement was obtained between experiment and simulation, although the simulations generally underestimated phonation threshold pressure and onset frequency. The clinical implications of the results of this study are also discussed. PMID:22978891

  5. Asymmetric vibration in a two-layer vocal fold model with left-right stiffness asymmetry: experiment and simulation.

    PubMed

    Zhang, Zhaoyan; Luu, Trung Hieu

    2012-09-01

    Vibration characteristics of a self-oscillating two-layer vocal fold model with left-right asymmetry in body-layer stiffness were experimentally and numerically investigated. Two regimes of distinct vibratory pattern were identified as a function of left-right stiffness mismatch. In the first regime with extremely large left-right stiffness mismatch, phonation onset resulted from an eigenmode synchronization process that involved only eigenmodes of the soft fold. Vocal fold vibration in this regime was dominated by a large-amplitude vibration of the soft fold, and phonation frequency was determined by the properties of the soft fold alone. The stiff fold was only enslaved to vibrate at a much reduced amplitude. In the second regime with small left-right stiffness mismatch, eigenmodes of both folds actively participated in the eigenmode synchronization process. The two folds vibrated with comparable amplitude, but the stiff fold consistently led the soft fold in phase for all conditions. A qualitatively good agreement was obtained between experiment and simulation, although the simulations generally underestimated phonation threshold pressure and onset frequency. The clinical implications of the results of this study are also discussed.

  6. Cause-effect relationship between vocal fold physiology and voice production in a three-dimensional phonation model

    PubMed Central

    Zhang, Zhaoyan

    2016-01-01

    The goal of this study is to better understand the cause-effect relation between vocal fold physiology and the resulting vibration pattern and voice acoustics. Using a three-dimensional continuum model of phonation, the effects of changes in vocal fold stiffness, medial surface thickness in the vertical direction, resting glottal opening, and subglottal pressure on vocal fold vibration and different acoustic measures are investigated. The results show that the medial surface thickness has dominant effects on the vertical phase difference between the upper and lower margins of the medial surface, closed quotient, H1-H2, and higher-order harmonics excitation. The main effects of vocal fold approximation or decreasing resting glottal opening are to lower the phonation threshold pressure, reduce noise production, and increase the fundamental frequency. Increasing subglottal pressure is primarily responsible for vocal intensity increase but also leads to significant increase in noise production and an increased fundamental frequency. Increasing AP stiffness significantly increases the fundamental frequency and slightly reduces noise production. The interaction among vocal fold thickness, stiffness, approximation, and subglottal pressure in the control of F0, vocal intensity, and voice quality is discussed. PMID:27106298

  7. Reducing the negative vocal effects of superficial laryngeal dehydration with humidification.

    PubMed

    Levendoski, Elizabeth Erickson; Sundarrajan, Anusha; Sivasankar, M Preeti

    2014-07-01

    Environmental humidification is a simple, cost-effective method believed to reduce superficial laryngeal drying. This study sought to validate this belief by investigating whether humidification treatment would reduce the negative effects of superficial laryngeal dehydration on phonation threshold pressure (PTP). Phonation threshold pressure data analysis may be vulnerable to bias because of lack of investigator blinding. Consequently, this study investigated the extent of PTP analysis reliability between unblinded and blinded investigators. Healthy male and female adults were assigned to a vocal fatigue (n = 20) or control group (n = 20) based on their responses to a questionnaire. PTP was assessed after 2 hours of mouth breathing in low humidity (dehydration challenge), following a 5-minute break in ambient humidity, and after 2 hours of mouth breathing in high humidity (humidification). PTP significantly increased following the laryngeal dehydration challenge. After humidification, PTP returned toward baseline. These effects were observed in both subject groups. PTP measurements were highly correlated between the unblinded and blinded investigator. Humidification may be an effective approach to decrease the detrimental voice effects of superficial laryngeal dehydration. These data lay the foundation for future investigations aimed at preventing and treating the negative voice changes associated with chronic, surface laryngeal drying.

  8. Adapted to Roar: Functional Morphology of Tiger and Lion Vocal Folds

    PubMed Central

    Klemuk, Sarah A.; Riede, Tobias; Walsh, Edward J.; Titze, Ingo R.

    2011-01-01

    Vocal production requires active control of the respiratory system, larynx and vocal tract. Vocal sounds in mammals are produced by flow-induced vocal fold oscillation, which requires vocal fold tissue that can sustain the mechanical stress during phonation. Our understanding of the relationship between morphology and vocal function of vocal folds is very limited. Here we tested the hypothesis that vocal fold morphology and viscoelastic properties allow a prediction of fundamental frequency range of sounds that can be produced, and minimal lung pressure necessary to initiate phonation. We tested the hypothesis in lions and tigers who are well-known for producing low frequency and very loud roaring sounds that expose vocal folds to large stresses. In histological sections, we found that the Panthera vocal fold lamina propria consists of a lateral region with adipocytes embedded in a network of collagen and elastin fibers and hyaluronan. There is also a medial region that contains only fibrous proteins and hyaluronan but no fat cells. Young's moduli range between 10 and 2000 kPa for strains up to 60%. Shear moduli ranged between 0.1 and 2 kPa and differed between layers. Biomechanical and morphological data were used to make predictions of fundamental frequency and subglottal pressure ranges. Such predictions agreed well with measurements from natural phonation and phonation of excised larynges, respectively. We assume that fat shapes Panthera vocal folds into an advantageous geometry for phonation and it protects vocal folds. Its primary function is probably not to increase vocal fold mass as suggested previously. The large square-shaped Panthera vocal fold eases phonation onset and thereby extends the dynamic range of the voice. PMID:22073246

  9. Power Flow in Phonation

    NASA Astrophysics Data System (ADS)

    Zhang, Lucy; Yu, Feimi; Krane, Michael

    2017-11-01

    The control volume analysis of power flow during sustained phonation is performed using results of a fully-coupled aeroelastic-aeroacoustic simulation. The control volumes consist of the laryngeal region, and the larynx and the vocal tract. Two cases are considered: an effectively infinite length vocal tract, where sound produced in the larynx radiates away and is not reflected back, and a constant-area vocal tract of normal adult human dimensions, in which phonatory sound resonates before radiating from the mouth opening. In both cases the lungs are modeled to absorb all incident sound, while providing a constant volume flow toward the larynx. Control of the acoustic boundary conditions is accomplished using perfectly matched- layers, and flow from the lungs is provided by a source distribution near the entrance to the trachea region. For both cases the power flow for the larynx and larynx plus vocal tract control volumes are computed using the integral form of the mechanical energy equation, expanded to consider power exchanges between slightly compressible flow in the larynx and the acoustic fields in the vocal tract and trachea. The funding from NIH 2R01DC005642-10A1 is greatly acknowledged.

  10. Aeroacoustic analysis of the human phonation process based on a hybrid acoustic PIV approach

    NASA Astrophysics Data System (ADS)

    Lodermeyer, Alexander; Tautz, Matthias; Becker, Stefan; Döllinger, Michael; Birk, Veronika; Kniesburges, Stefan

    2018-01-01

    The detailed analysis of sound generation in human phonation is severely limited as the accessibility to the laryngeal flow region is highly restricted. Consequently, the physical basis of the underlying fluid-structure-acoustic interaction that describes the primary mechanism of sound production is not yet fully understood. Therefore, we propose the implementation of a hybrid acoustic PIV procedure to evaluate aeroacoustic sound generation during voice production within a synthetic larynx model. Focusing on the flow field downstream of synthetic, aerodynamically driven vocal folds, we calculated acoustic source terms based on the velocity fields obtained by time-resolved high-speed PIV applied to the mid-coronal plane. The radiation of these sources into the acoustic far field was numerically simulated and the resulting acoustic pressure was finally compared with experimental microphone measurements. We identified the tonal sound to be generated downstream in a small region close to the vocal folds. The simulation of the sound propagation underestimated the tonal components, whereas the broadband sound was well reproduced. Our results demonstrate the feasibility to locate aeroacoustic sound sources inside a synthetic larynx using a hybrid acoustic PIV approach. Although the technique employs a 2D-limited flow field, it accurately reproduces the basic characteristics of the aeroacoustic field in our larynx model. In future studies, not only the aeroacoustic mechanisms of normal phonation will be assessable, but also the sound generation of voice disorders can be investigated more profoundly.

  11. Effects of exposure to sulfur mustard on speech aerodynamics.

    PubMed

    Heydari, Fatemeh; Ghanei, Mostafa

    2011-01-01

    Sulfur mustard is an alkylating agent with highly cytotoxic properties even at low exposure. It was used widely against both military and civilian population by Iraqi forces in the Iraq-Iran war (1983-1988). Although various aspects of mustard gas effects on patients with chemical injury have been relatively well characterized, its effects on speech are still evolving. We evaluated aerodynamics of speech in male patients following sulfur mustard inhalation. In a case-control study patients with chemical injuries (n=19) along with age and sex-matched healthy control group (n=20) were selected. Aerodynamic analyses were performed by using the Glasgow Airflow Measurement System (known as ST1 dysphonia). Results indicated that except mean flow rate, there were statistically significant differences in vital capacity, phonation time, phonation volume, vocal velocity index, total expired volume and phonation quotient of patients between experimental and control groups (P<0.05). This study demonstrated mustard gas can impair different parameters of speech aerodynamics. As a result of this activity, the reader will be able to describe: (1) the evaluation of air flow in relation to speech system dysfunction and efficiency; (2) the effect of sulfur mustard known as mustard gas on respiratory physiology. Copyright © 2011 Elsevier Inc. All rights reserved.

  12. Study of non-linear deformation of vocal folds in simulations of human phonation

    NASA Astrophysics Data System (ADS)

    Saurabh, Shakti; Bodony, Daniel

    2014-11-01

    Direct numerical simulation is performed on a two-dimensional compressible, viscous fluid interacting with a non-linear, viscoelastic solid as a model for the generation of the human voice. The vocal fold (VF) tissues are modeled as multi-layered with varying stiffness in each layer and using a finite-strain Standard Linear Solid (SLS) constitutive model implemented in a quadratic finite element code and coupled to a high-order compressible Navier-Stokes solver through a boundary-fitted fluid-solid interface. The large non-linear mesh deformation is handled using an elliptic/poisson smoothening technique. Supra-glottal flow shows asymmetry in the flow, which in turn has a coupling effect on the motion of the VF. The fully compressible simulations gives direct insight into the sound produced as pressure distributions and the vocal fold deformation helps study the unsteady vortical flow resulting from the fluid-structure interaction along the full phonation cycle. Supported by the National Science Foundation (CAREER Award Number 1150439).

  13. Modeling coupled aerodynamics and vocal fold dynamics using immersed boundary methods.

    PubMed

    Duncan, Comer; Zhai, Guangnian; Scherer, Ronald

    2006-11-01

    The penalty immersed boundary (PIB) method, originally introduced by Peskin (1972) to model the function of the mammalian heart, is tested as a fluid-structure interaction model of the closely coupled dynamics of the vocal folds and aerodynamics in phonation. Two-dimensional vocal folds are simulated with material properties chosen to result in self-oscillation and volume flows in physiological frequency ranges. Properties of the glottal flow field, including vorticity, are studied in conjunction with the dynamic vocal fold motion. The results of using the PIB method to model self-oscillating vocal folds for the case of 8 cm H20 as the transglottal pressure gradient are described. The volume flow at 8 cm H20, the transglottal pressure, and vortex dynamics associated with the self-oscillating model are shown. Volume flow is also given for 2, 4, and 12 cm H2O, illustrating the robustness of the model to a range of transglottal pressures. The results indicate that the PIB method applied to modeling phonation has good potential for the study of the interdependence of aerodynamics and vocal fold motion.

  14. Estimating perceived phonatory pressedness in singing from flow glottograms.

    PubMed

    Sundberg, Johan; Thalén, Margareta; Alku, Paavo; Vilkman, Erkki

    2004-03-01

    The normalized amplitude quotient (NAQ), defined as the ratio between the peak-to-peak amplitude of the flow pulse and the negative peak amplitude of the differentiated flow glottogram and normalized with respect to period time, has been shown to be related to glottal adduction. Glottal adduction, in turn, affects mode of phonation and hence perceived phonatory pressedness. The relationship between NAQ and perceived phonatory pressedness was analyzed in a material collected from a professional female singer and singing teacher who sang a triad pattern in breathy, flow, neutral, and pressed phonation in three different loudness conditions (soft, middle, loud). In addition, she also sang the same triad pattern in four different styles of singing, classical, pop, jazz, and blues, in the same three loudness conditions. A panel of experts rated the degree of perceived phonatory press along visual analogue scales. Comparing the obtained mean rated pressedness ratings with the mean NAQ values for the various triads showed that about 73% of the variation in perceived pressedness could be accounted for by variations of NAQ.

  15. Dependence of phonatory effort on hydration level.

    PubMed

    Verdolini, K; Titze, I R; Fennell, A

    1994-10-01

    In this study, a double-blind placebo-controlled approach was used to assess the relation between hydration level and phonatory effort. Twelve adult, untrained voice users with normal voices participated as subjects. Each subject received a 4-hour hydration treatment, a 4-hour dehydration treatment, and a 4-hour placebo (control) treatment. Following each treatment, phonatory effort was measured with a physiological measure, phonation threshold pressure (PTP), and with a psychological measure, direct magnitude estimation of perceived phonatory effort (DMEPPE). Summarizing the results across these measures, the findings indicated an inverse relation between phonatory effort and hydration level, but primarily for high-pitched phonation tasks. The findings for PTPs replicated those from an earlier study conducted without double-blind experimental manipulations (Verdolini-Marston, Titze, & Druker, 1990). Theoretical discussion focuses on the possible role of vocal fold tissue viscosity for hydration and dehydration effects, although direct measures of tissue viscosity are lacking.

  16. Vocal function and upper airway thermoregulation in five different environmental conditions.

    PubMed

    Sandage, Mary J; Connor, Nadine P; Pascoe, David D

    2014-02-01

    Phonation threshold pressure and perceived phonatory effort were hypothesized to increase and upper airway temperature to decrease following exposure to cold and/or dry air. Greater changes were expected with mouth versus nose breathing. In a within-participant repeated measures design, 15 consented participants (7 men, 8 women) completed 20-min duration trials to allow for adequate thermal equilibration for both nose and mouth breathing in 5 different environments: 3 temperatures (°C) matched for relative humidity (% RH), cold (15 °C, 40% RH), thermally neutral (25 °C, 40% RH), and hot (35 °C, 40% RH); and 2 temperatures with variable relative humidity to match vapor pressure for the neutral environment (25 °C, 40% RH), cold (15 °C, 74% RH) and hot (35 °C, 23% RH). Following each equilibration trial, measures were taken in this order: upper airway temperature (transnasal thermistor probe), phonation threshold pressure, and perceived phonatory effort. Data were analyzed using repeated measures analysis of variance, and no significant differences were established. The study hypotheses were not supported. Findings suggest that the upper airway is tightly regulated for temperature when challenged by a realistic range of temperature and relative humidity environments. This is the first study of its kind to include measurement of upper airway temperature in conjunction with measures of vocal function.

  17. Reducing the Negative Vocal Effects of Superficial Laryngeal Dehydration With Humidification

    PubMed Central

    Levendoski, Elizabeth Erickson; Sundarrajan, Anusha; Sivasankar, M. Preeti

    2017-01-01

    Objectives Environmental humidification is a simple, cost-effective method believed to reduce superficial laryngeal drying. This study sought to validate this belief by investigating whether humidification treatment would reduce the negative effects of superficial laryngeal dehydration on phonation threshold pressure (PTP). Phonation threshold pressure data analysis may be vulnerable to bias because of lack of investigator blinding. Consequently, this study investigated the extent of PTP analysis reliability between unblinded and blinded investigators. Methods Healthy male and female adults were assigned to a vocal fatigue (n = 20) or control group (n = 20) based on their responses to a questionnaire. PTP was assessed after 2 hours of mouth breathing in low humidity (dehydration challenge), following a 5-minute break in ambient humidity, and after 2 hours of mouth breathing in high humidity (humidification). Results PTP significantly increased following the laryngeal dehydration challenge. After humidification, PTP returned toward baseline. These effects were observed in both subject groups. PTP measurements were highly correlated between the unblinded and blinded investigator. Conclusions Humidification may be an effective approach to decrease the detrimental voice effects of superficial laryngeal dehydration. These data lay the foundation for future investigations aimed at preventing and treating the negative voice changes associated with chronic, surface laryngeal drying. PMID:24690983

  18. Flow fields and acoustics in a unilateral scarred vocal fold model.

    PubMed

    Murugappan, Shanmugam; Khosla, Sid; Casper, Keith; Oren, Liran; Gutmark, Ephraim

    2009-01-01

    From prior work in an excised canine larynx model, it has been shown that intraglottal vortices form between the vocal folds during the latter part of closing. It has also been shown that the vortices generate a negative pressure between the folds, producing a suction force that causes sudden, rapid closing of the folds. This rapid closing will produce increased loudness and increased higher harmonics. We used a unilateral scarred excised canine larynx model to determine whether the intraglottal vortices and resulting acoustics were changed, compared to those of normal larynges. Acoustic, flow field, and high-speed imaging measurements from 5 normal and 5 unilaterally scarred canine larynges are presented in this report. Scarring was produced by complete resection of the vocal fold mucosa and superficial layer of the lamina propria on the right vocal fold only. Two months later, these dogs were painlessly sacrificed, and testing was done on the excised larynges during phonation. High-speed video imaging was then used to measure vocal fold displacement during different phases. Particle image velocimetry and acoustic measurements were used to describe possible acoustic effects of the vortices. A higher phonation threshold was required to excite the motion of the vocal fold in scarred larynges. As the subglottal pressure increased, the strength of the vortices and the higher harmonics both consistently increased. However, it was seen that increasing the maximum displacement of the scarred fold did not consistently increase the higher harmonics. The improvements that result from increasing subglottal pressure may be due to a combination of increasing the strength of the intraglottal vortices and increasing the maximum displacement of the vocal fold; however, the data in this study suggest that the vortices play a much more important role. The current study indicates that higher subglottal pressures may excite higher harmonics and improve loudness for patients with unilateral vocal fold scarring. This finding implies that therapies that raise the subglottal pressure may be helpful in improving voice quality.

  19. Effects of a Straw Phonation Protocol on Acoustic Measures of an SATB Chorus Singing Two Contrasting Renaissance Works.

    PubMed

    Manternach, Jeremy N; Clark, Chad; Daugherty, James F

    2017-07-01

    Researchers have found that semi-occluded vocal tract (SOVT) exercises may increase vocal economy by reducing phonation threshold pressure and effort while increasing or maintaining consistent acoustic output. This research has focused solely on individual singers. Much singing instruction, however, takes place in choral settings. Choral singers may use different resonance strategies or unconsciously adjust their singing based on the ability to hear their own sound in relation to others. Results of studies with individual singers, then, may not be directly applicable to choral settings. The purpose of this investigation was to measure the effect of an SOVT protocol (ie, straw phonation) on acoustic changes of conglomerate, choral sound. This is a quasi-experimental, one-group, pretest-posttest design. Participants in this study constituted an intact SATB choir (soprano, alto, tenor, and bass) (N = 15 singers) who performed from memory two unaccompanied pieces of varied tempos from memory, participated in a 4-minute straw phonation protocol with a small stirring straw, and then sang each piece a second time. The long-term average spectrum results indicated small, statistically significant increases in spectral energy for both pieces in the 0-10 kHz (.32 and .20 dB Sound Pressure Level) and 2-4 kHz regions (.46 and .25 dB SPL). These results, although not likely audible to average hearing humans, seem consistent with the assertion that singers enjoy vocal benefits with consistent or increased vocal output. SOVT exercises, therefore, may be useful as a time-efficient way to evoke more efficient and economical singing during choral warm-up and voice building procedures. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  20. Theoretical Analysis of Maximum Flow Declination Rate versus Maximum Area Declination Rate in Phonation

    ERIC Educational Resources Information Center

    Titze, Ingo R.

    2006-01-01

    Purpose: Maximum flow declination rate (MFDR) in the glottis is known to correlate strongly with vocal intensity in voicing. This declination, or negative slope on the glottal airflow waveform, is in part attributable to the maximum area declination rate (MADR) and in part to the overall inertia of the air column of the vocal tract (lungs to…

  1. An immersed-boundary method for flow–structure interaction in biological systems with application to phonation

    PubMed Central

    Luo, Haoxiang; Mittal, Rajat; Zheng, Xudong; Bielamowicz, Steven A.; Walsh, Raymond J.; Hahn, James K.

    2008-01-01

    A new numerical approach for modeling a class of flow–structure interaction problems typically encountered in biological systems is presented. In this approach, a previously developed, sharp-interface, immersed-boundary method for incompressible flows is used to model the fluid flow and a new, sharp-interface Cartesian grid, immersed boundary method is devised to solve the equations of linear viscoelasticity that governs the solid. The two solvers are coupled to model flow–structure interaction. This coupled solver has the advantage of simple grid generation and efficient computation on simple, single-block structured grids. The accuracy of the solid-mechanics solver is examined by applying it to a canonical problem. The solution methodology is then applied to the problem of laryngeal aerodynamics and vocal fold vibration during human phonation. This includes a three-dimensional eigen analysis for a multi-layered vocal fold prototype as well as two-dimensional, flow-induced vocal fold vibration in a modeled larynx. Several salient features of the aerodynamics as well as vocal-fold dynamics are presented. PMID:19936017

  2. Duration of sustained phonation in kindergarten children.

    PubMed

    Harden, J R; Looney, N A

    1984-03-01

    Maximum sustained phonations of the vowels [a], [u] and [i] were obtained from 160 kindergarten children with a mean age of approximately 6.2 years. Subjects were grouped by sex and by the presence or absence of a voice disorder. Stop watch measurements of each subject's maximum phonations were compared with graphic level recorder measurements of those phonations . The results indicated that (1) the factor of sex had no significant effect on maximum phonation times; (2) the factor of voice group (non-voice-disordered/voice-disordered) did result in a significant effect (P less than 0.01) with the voice-disordered group achieving shorter phonations than the non-voice-disordered group; (3) the phonation times obtained from the two measurement procedures correlate significantly (P less than 0.05). Results also suggest that the vowel effect on maximum phonation time was significant (P less than 0.05) for both groups. The vowel [i] was phonated significantly longer than either [a] or [u] for males and females in both groups.

  3. Glottal volume velocity waveform characteristics in subjects with and without vocal training, related to gender, sound intensity, fundamental frequency, and age.

    PubMed

    Sulter, A M; Wit, H P

    1996-11-01

    Glottal volume velocity waveform characteristics of 224 subjects, categorized in four groups according to gender and vocal training, were determined, and their relations to sound-pressure level, fundamental frequency, intra-oral pressure, and age were analyzed. Subjects phonated at three intensity conditions. The glottal volume velocity waveforms were obtained by inverse filtering the oral flow. Glottal volume velocity waveforms were parameterized with flow-based (minimum flow, ac flow, average flow, maximum flow declination rate) and time-based parameters (closed quotient, closing quotient, speed quotient), as well as with derived parameters (vocal efficiency and glottal resistance). Higher sound-pressure levels, intra-oral pressures, and flow-parameter values (ac flow, maximum flow declination rate) were observed, when compared with previous investigations. These higher values might be the result of the specific phonation tasks (stressed /ae/ vowel in a word and a sentence) or filtering processes. Few statistically significant (p < 0.01) differences in parameters were found between untrained and trained subjects [the maximum flow declination rate and the closing quotient were higher in trained women (p < 0.001), and the speed quotient was higher in trained men (p < 0.005)]. Several statistically significant parameter differences were found between men and women [minimum flow, ac flow, average flow, maximum flow declination rate, closing quotient, glottal resistance (p < 0.001), and closed quotient (p < 0.005)]. Significant effects of intensity condition were observed on ac flow, maximum flow declination rate, closing quotient, and vocal efficiency in women (p < 0.005), and on minimum flow, ac flow, average flow, maximum flow declination rate, closed quotient, and vocal efficiency in men (p < 0.01).

  4. Altered vocal fold kinematics in synthetic self-oscillating models that employ adipose tissue as a lateral boundary condition.

    NASA Astrophysics Data System (ADS)

    Saidi, Hiba; Erath, Byron D.

    2015-11-01

    The vocal folds play a major role in human communication by initiating voiced sound production. During voiced speech, the vocal folds are set into sustained vibrations. Synthetic self-oscillating vocal fold models are regularly employed to gain insight into flow-structure interactions governing the phonation process. Commonly, a fixed boundary condition is applied to the lateral, anterior, and posterior sides of the synthetic vocal fold models. However, physiological observations reveal the presence of adipose tissue on the lateral surface between the thyroid cartilage and the vocal folds. The goal of this study is to investigate the influence of including this substrate layer of adipose tissue on the dynamics of phonation. For a more realistic representation of the human vocal folds, synthetic multi-layer vocal fold models have been fabricated and tested while including a soft lateral layer representative of adipose tissue. Phonation parameters have been collected and are compared to those of the standard vocal fold models. Results show that vocal fold kinematics are affected by adding the adipose tissue layer as a new boundary condition.

  5. Correlation of phonatory behavior with vocal fold structure, observed in a physical model

    NASA Astrophysics Data System (ADS)

    Krane, Michael; Walters, Gage; McPhail, Michael

    2017-11-01

    The effect of vocal fold shape and internal structure on phonation was studied experimentally using a physical model of the human airway. Model folds used a ``M5'' or a swept ellipse coronal cross-section shape. Models were molded in either 2 or three layers. Two-layer models included a more stiff ``body'' layer and a much softer ``cover'' layer, while the 3-layer models also incorporated an additional, thin, ``ligament/conus'' layer stiffer than the body layer. The elliptical section models were all molded in 3 such layers. Measurements of transglottal pressure, volume flow, mouth sound pressure, and high-speed imaging of vocal fold vibration were performed. These show that models with the ``ligament'' layer experienced much attenuated vertical deformation, that glottal closure was more likely, and that phonation was much easier to initiate. These findings suggest that the combination of the vocal ligament and the conus elasticus stabilize the vocal fold for efficient phonation by limiting vertical deformation, while allowing transverse deformations to occur. Acknowledge support from NIH DC R01005642-11.

  6. Vocal Function and Upper Airway Thermoregulation in Five Different Environmental Conditions

    PubMed Central

    Sandage, Mary J.; Connor, Nadine P.; Pascoe, David D.

    2013-01-01

    Purpose Phonation threshold pressure and perceived phonatory effort were hypothesized to increase and upper airway temperature decrease following exposure to cold and/or dry air. Greater changes were expected with mouth versus nose breathing. Method Using a within-participant repeated measures design, 15 consented participants (7 men, 8 women) completed 20-minute duration trials to allow for adequate thermal equilibration for both nose and mouth breathing in five different environments: three temperatures (°C) matched for relative humidity (%RH): cold (15°C/40% RH), thermally neutral (25°C/40% RH), and hot (35°C/40% RH); and two temperatures with variable relative humidity to match vapor pressure for the neutral environment (25°C/40% RH): cold (15°C/74% RH) and hot (35°C; 23% RH). Following each equilibration trial, measures were taken in this order: upper airway temperature (transnasal thermistor probe), phonation threshold pressure, and perceived phonatory effort. Results Data were analyzed using repeated measures analysis of variance and no significant differences were established. Conclusions The study hypotheses were not supported. Findings suggest that the upper airway is tightly regulated for temperature when challenged by a realistic range of temperature/relative humidity environments. This is the first study of its kind to include measurement of upper airway temperature in conjunction with measures of vocal function. PMID:23900031

  7. A lumped mucosal wave model of the vocal folds revisited: Recent extensions and oscillation hysteresis

    PubMed Central

    Lucero, Jorge C.; Koenig, Laura L.; Lourenço, Kelem G.; Ruty, Nicolas; Pelorson, Xavier

    2011-01-01

    This paper examines an updated version of a lumped mucosal wave model of the vocal fold oscillation during phonation. Threshold values of the subglottal pressure and the mean (DC) glottal airflow for the oscillation onset are determined. Depending on the nonlinear characteristics of the model, an oscillation hysteresis phenomenon may occur, with different values for the oscillation onset and offset threshold. The threshold values depend on the oscillation frequency, but the occurrence of the hysteresis is independent of it. The results are tested against pressure data collected from a mechanical replica of the vocal folds, and oral airflow data collected from speakers producing intervocalic ∕h∕. In the human speech data, observed differences between voice onset and offset may be attributed to variations in voice pitch, with a very small or inexistent hysteresis phenomenon. PMID:21428520

  8. CHARACTERIZATION OF FLOW-RESISTANT TUBES USED FOR SEMI-OCCLUDED VOCAL TRACT VOICE TRAINING AND THERAPY

    PubMed Central

    Smith, Simeon L.; Titze, Ingo R.

    2016-01-01

    Objectives To characterize the pressure-flow relationship of tubes used for semi-occluded vocal tract voice training/therapy, as well as to answer these major questions: (1) What is the relative importance of tube length to tube diameter? (2) What is the range of oral pressures achieved with tubes at phonation flow rates? (3) Does mouth configuration behind the tubes matter? Methods Plastic tubes of various diameters and lengths were mounted in line with an upstream pipe, and the pressure drop across each tube was measured at stepwise increments in flow rate. Basic flow theory and modified flow theory equations were used to describe the pressure-flow relationship of the tubes based on diameter and length. Additionally, the upstream pipe diameter was varied to explore how mouth shape affects tube resistance. Results The modified equation provided an excellent prediction of the pressure-flow relationship across all tube sizes (6% error compared to the experimental data). Variation in upstream pipe diameter yielded up to 10% deviation in pressure for tube sizes typically used in voice training/therapy. Conclusions Using the presented equations, resistance can be characterized for any tube based on diameter, length, and flow rate. With regard to the original questions, we found that: (1) For commonly used tubes, diameter is the critical variable for governing flow resistance; (2) For phonation flow rates, a range of tube dimensions produced pressures between 0 and 7.0 kPa; (3) The mouth pressure behind the lips will vary slightly with different mouth shapes, but this effect can be considered relatively insignificant. PMID:27133001

  9. Experimental analysis of the characteristics of artificial vocal folds.

    PubMed

    Misun, Vojtech; Svancara, Pavel; Vasek, Martin

    2011-05-01

    Specialized literature presents a number of models describing the function of the vocal folds. In most of those models, an emphasis is placed on the air flowing through the glottis and, further, on the effect of the parameters of the air alone (its mass, speed, and so forth). The article focuses on the constructional definition of artificial vocal folds and their experimental analysis. The analysis is conducted for voiced source voice phonation and for the changing mean value of the subglottal pressure. The article further deals with the analysis of the pressure of the airflow through the vocal folds, which is cut (separated) into individual pulses by the vibrating vocal folds. The analysis results show that air pulse characteristics are relevant to voice generation, as they are produced by the flowing air and vibrating vocal folds. A number of artificial vocal folds have been constructed to date, and the aforementioned view of their phonation is confirmed by their analysis. The experiments have confirmed that man is able to consciously affect only two parameters of the source voice, that is, its fundamental frequency and voice intensity. The main forces acting on the vocal folds during phonation are as follows: subglottal air pressure and elastic and inertia forces of the vocal folds' structure. The correctness of the function of the artificial vocal folds is documented by the experimental verification of the spectra of several types of artificial vocal folds. Copyright © 2011 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  10. Simultaneous temporally resolved DPIV and pressure measurements of symmetric oscillations in a scaled-up vocal fold model

    NASA Astrophysics Data System (ADS)

    Ringenberg, Hunter; Rogers, Dylan; Wei, Nathaniel; Krane, Michael; Wei, Timothy

    2017-11-01

    The objective of this study is to apply experimental data to theoretical framework of Krane (2013) in which the principal aeroacoustic source is expressed in terms of vocal fold drag, glottal jet dynamic head, and glottal exit volume flow, reconciling formal theoretical aeroacoustic descriptions of phonation with more traditional lumped-element descriptions. These quantities appear in the integral equations of motion for phonatory flow. In this way time resolved velocity field measurements can be used to compute time-resolved estimates of the relevant terms in the integral equations of motion, including phonation aeroacoustic source strength. A simplified 10x scale vocal fold model from Krane, et al. (2007) was used to examine symmetric, i.e. `healthy', oscillatory motion of the vocal folds. By using water as the working fluid, very high spatial and temporal resolution was achieved. Temporal variation of transglottal pressure was simultaneously measured with flow on the vocal fold model mid-height. Experiments were dynamically scaled to examine a range of frequencies corresponding to male and female voice. The simultaneity of the pressure and flow provides new insights into the aeroacoustics associated with vocal fold oscillations. Supported by NIH Grant No. 2R01 DC005642-11.

  11. Investigation of prescribed movement in fluid–structure interaction simulation for the human phonation process☆

    PubMed Central

    Zörner, S.; Kaltenbacher, M.; Döllinger, M.

    2013-01-01

    In a partitioned approach for computational fluid–structure interaction (FSI) the coupling between fluid and structure causes substantial computational resources. Therefore, a convenient alternative is to reduce the problem to a pure flow simulation with preset movement and applying appropriate boundary conditions. This work investigates the impact of replacing the fully-coupled interface condition with a one-way coupling. To continue to capture structural movement and its effect onto the flow field, prescribed wall movements from separate simulations and/or measurements are used. As an appropriate test case, we apply the different coupling strategies to the human phonation process, which is a highly complex interaction of airflow through the larynx and structural vibration of the vocal folds (VF). We obtain vocal fold vibrations from a fully-coupled simulation and use them as input data for the simplified simulation, i.e. just solving the fluid flow. All computations are performed with our research code CFS++, which is based on the finite element (FE) method. The presented results show that a pure fluid simulation with prescribed structural movement can substitute the fully-coupled approach. However, caution must be used to ensure accurate boundary conditions on the interface, and we found that only a pressure driven flow correctly responds to the physical effects when using specified motion. PMID:24204083

  12. Oral breathing challenge in participants with vocal attrition.

    PubMed

    Sivasankar, Mahalakshmi; Fisher, Kimberly V

    2003-12-01

    Vocal folds undergo osmotic challenge by mouth breathing during singing, exercising, and loud speaking. Just 15 min of obligatory oral breathing, to dry the vocal folds, increases phonation threshold pressure (Pth) and expiratory vocal effort in healthy speakers (M. Sivasankar & K. Fisher, 2002). We questioned whether oral breathing is more detrimental to phonation in healthy participants with a history of temporary vocal attrition. The effects of a 15-min oral or nasal breathing challenge on Pth and perceived expiratory vocal effort were compared for participants reporting symptoms of vocal attrition (N = 18, ages 19-38 years) and normal controls (N = 20, ages 19-33 years). Post-challenge-prechallenge differences in Pth (deltaPth) and effort (deltaEffort) revealed that oral breathing, but not nasal breathing, increased Pth (p < .001 ) and effort (p < .001) at low, comfortable, and high pitch. deltaPth was significantly greater in participants with vocal attrition than in normal controls (p < .001). Nasal breathing reduced Pth for all controls but not for all participants reporting vocal attrition. deltaPth was significantly and linearly correlated with deltaEffort (rvocal attrition = .81, p < .001; rcontrol = .84, p < .001). We speculate that the greater increases in Pth in participants reporting vocal attrition may result from delayed or inadequate compensatory response to superficial laryngeal dehydration. Obligatory oral breathing may place voice users at risk for exacerbating vocal attrition. That sol layer depletion by obligatory oral breathing increased Pth and vocal effort provides support for the role of superficial hydration in maintaining ease of phonation.

  13. Determination of Phonation Instability Pressure and Phonation Pressure Range in Excised Larynges

    ERIC Educational Resources Information Center

    Zhang, Yu; Reynders, William J.; Jiang, Jack J.; Tateya, Ichiro

    2007-01-01

    Purpose: The present study was a methodological study designed to reveal the dynamic mechanisms of phonation instability pressure (PIP) using bifurcation analysis. Phonation pressure range (PPR) was also proposed for assessing the pressure range of normal vocal fold vibrations. Method: The authors first introduced the concept of bifurcation on the…

  14. A lumped mucosal wave model of the vocal folds revisited: recent extensions and oscillation hysteresis.

    PubMed

    Lucero, Jorge C; Koenig, Laura L; Lourenço, Kelem G; Ruty, Nicolas; Pelorson, Xavier

    2011-03-01

    This paper examines an updated version of a lumped mucosal wave model of the vocal fold oscillation during phonation. Threshold values of the subglottal pressure and the mean (DC) glottal airflow for the oscillation onset are determined. Depending on the nonlinear characteristics of the model, an oscillation hysteresis phenomenon may occur, with different values for the oscillation onset and offset threshold. The threshold values depend on the oscillation frequency, but the occurrence of the hysteresis is independent of it. The results are tested against pressure data collected from a mechanical replica of the vocal folds, and oral airflow data collected from speakers producing intervocalic /h/. In the human speech data, observed differences between voice onset and offset may be attributed to variations in voice pitch, with a very small or inexistent hysteresis phenomenon. © 2011 Acoustical Society of America

  15. Relationship of Various Open Quotients With Acoustic Property, Phonation Types, Fundamental Frequency, and Intensity.

    PubMed

    Yokonishi, Hisayuki; Imagawa, Hiroshi; Sakakibara, Ken-Ichi; Yamauchi, Akihito; Nito, Takaharu; Yamasoba, Tatsuya; Tayama, Niro

    2016-03-01

    In the present study, we examined the relationship between various open quotients (Oqs) and phonation types, fundamental frequency (F0), and intensity by multivariate linear regression analysis (MVA) to determine which Oq best reflects vocal fold vibratory characteristics. Using high-speed digital imaging (HSDI), a sustained vowel /e/ at different phonation types, F0s, and intensities was recorded from six vocally healthy male volunteers: the types of phonation included modal, falsetto, modal breathy, and modal pressed phonations; and each phonation was performed at different F0s and intensities. Electroglottography (EGG) and sound signals were simultaneously recorded with HSDI. From the obtained data, 10 conventional Oqs (four Oqs from the glottal area function, four kymographic Oqs, and two EGG-derived Oqs) and two newly introduced Oqs (Oq(edge)+ and Oq(edge)) were evaluated. And, relationships between various Oqs and phonation types, F0, and intensity were evaluated by MVA. Among the various Oqs, Oq(edge)+ and Oq(edge) revealed the strongest correlations with an acoustic property and could best describe changes in phonation types: Oq(edge) was found to be better than Oq(edge)¯. Oq(MLK), the average of five Oqs from five-line multiline kymography was a very good alternative to Oq(edge)¯. EGG-derived Oqs were able to differentiate between modal phonation and falsetto phonation, but it was necessary to consider the change of F0 simultaneously. MVA showed the changes in Oq values between modal and other phonation types, the degree of involvement of intensity, and no relationship between F0 and Oqs. Among Oqs evaluated in this study, Oq(edge)+ and Oq(edge) were considered to best reflect the vocal fold vibratory characteristics. Copyright © 2016 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  16. Acoustic and Linguistic Interdependencies of Irregular Phonation

    DTIC Science & Technology

    2010-05-01

    duration in the word ’year’ for a specific TIMIT case. ’ axl " refers to the phonated portion of the ’ I" in ’year’ and ’q’ refers to the inegularly phonated...and trans glottal pressure. Different configurations of the 19 system can lead not only to modal voiced speech and 1I11~oiced speech (the "regular...irregular phonation, despite the fact that they have much more divergent ranges during modal phonation. Males Females Group Range ofIrregular Region 7 -78

  17. Do obesity and weight loss affect vocal function?

    PubMed

    Solomon, Nancy Pearl; Helou, Leah B; Dietrich-Burns, Katie; Stojadinovic, Alexander

    2011-02-01

    Obesity may be associated with increased tissue bulk in the laryngeal airway, neck, and chest wall, and as such may affect vocal function. Eight obese and eight nonobese adults participated in this study; the obese participants underwent bariatric surgical procedures. This mixed-design study included cross-sectional analysis for group differences and longitudinal analysis for multidimensional changes in vocal function from four assessments collected over 6 months. No significant differences were detected between groups from the preoperative assessment. Further, no changes were detected over time for acoustic parameters, maximum phonation time, laryngeal airway resistance, and airflow during a sustained vowel for either group. Only minor differences were detected for strain, pitch, and loudness perceptions of voice over time, but not between groups. Phonation threshold pressure (PTP), at comfortable and high pitches (30% and 80% of the F0 range) changed significantly over time, but not between groups. Examination of individual data revealed a trend for PTP at 30% F0 to decrease as body mass index decreased. PTP may be informative for assessing vocal function in clients who present with obesity and voice symptoms. © Thieme Medical Publishers.

  18. Phonatory Effects of Type I Thyroplasty Implant Shape and Depth of Medialization in Unilateral Vocal Fold Paralysis

    PubMed Central

    Orestes, Michael I.; Neubauer, Juergen; Sofer, Elazar; Salinas, Jonathon; Chhetri, Dinesh K.

    2015-01-01

    Objectives/Hypothesis Medialization thyroplasty (MT) is commonly used to treat glottic insufficiency. In this study, we investigated the phonatory effects of MT implant medialization depth and medial surface shape. Methods Recurrent laryngeal nerve (RLN) and vagal paralysis were simulated in an in vivo canine. A type 1 MT was performed using a silicone elastomer implant with variable medialization depths and medial surface shapes: rectangular, V-shaped, divergent, and convergent. The effects on phonation onset flow/pressure relationships and acoustics were measured. Results Increasing depth of medialization led to improvements in fundamental frequency (F0) range and normalization of the slope of pressure/flow relationship toward baseline activation conditions. The effects of implant medial shape also depended on depth of medialization. Outcome measures were similar among the implants at smaller medialization depths. With large medialization depths and vagal paralysis conditions, the divergent implant maintained pressure/flow relationship closer to baseline. The vagal paralysis conditions also demonstrated decreased fundamental frequency range and worse flow/pressure relationship compared to RLN paralysis. Conclusions The depth and medial shape of a medialization laryngoplasty (ML) implant significantly affect both the F0 range and aerodynamic power required for phonation. These effects become more notable with increasing depth of medialization. The study also illustrates that ML is less effective in vagal paralysis compared to RLN paralysis. PMID:25046146

  19. Development of myoelectric control type speaking valve with low flow resistance

    NASA Astrophysics Data System (ADS)

    Ooe, Katsutoshi; Sakurai, Kohei; Mimaki, Shinya

    2015-12-01

    We aimed to develop welfare devices for patients with phonation disorder. One of these devices is the electrical controltype speaking valve system. The conventional speaking valves have one-way valve architecture, they open when the user breathes in, and they close when user breathes out and produce voices. This type is very simple and tough, but some users feel closeness in case of exhalation without phonation. This problem is caused by its mechanism what can not be controlled by user's will. Therefore, we proposed an electrical control-type speaking valve system to resolve this problem. This valve is controlled by neck myoelectric signal of sternohyoid muscle. From our previous report, it was clarified that this valve had better performance about easy-to-breath. Furthermore, we proposed the compact myoelectric control-type speaking valve system. The new-type speaking valve was enough small to attach the human body, and its opening area is larger than that of conventional one. Additionally, we described the improvement of flow channel shape by using of FEM analysis. According to the result of the analysis, it was clarified that the shape-improved speaking valve gets the low flow resistance channel in case of inspiration. In this report, we tried to make the flow resistance lower by the shape of current plates, in case of both inspiration and exhalation. From the result of FEM analysis, our speaking valve could get better flow channel than older one.

  20. Some phonatory and resonatory characteristics of the rock, pop, soul, and Swedish dance band styles of singing.

    PubMed

    Borch, D Zangger; Sundberg, Johan

    2011-09-01

    This investigation aims at describing voice function of four nonclassical styles of singing, Rock, Pop, Soul, and Swedish Dance Band. A male singer, professionally experienced in performing in these genres, sang representative tunes, both with their original lyrics and on the syllable /pae/. In addition, he sang tones in a triad pattern ranging from the pitch Bb2 to the pitch C4 on the syllable /pae/ in pressed and neutral phonation. An expert panel was successful in classifying the samples, thus suggesting that the samples were representative of the various styles. Subglottal pressure was estimated from oral pressure during the occlusion for the consonant [p]. Flow glottograms were obtained from inverse filtering. The four lowest formant frequencies differed between the styles. The mean of the subglottal pressure and the mean of the normalized amplitude quotient (NAQ), that is, the ratio between the flow pulse amplitude and the product of period and maximum flow declination rate, were plotted against the mean of fundamental frequency. In these graphs, Rock and Swedish Dance Band assumed opposite extreme positions with respect to subglottal pressure and mean phonation frequency, whereas the mean NAQ values differed less between the styles. Copyright © 2011 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  1. Vocal Tract Adjustments of Dysphonic and Non-Dysphonic Women Pre- and Post-Flexible Resonance Tube in Water Exercise: A Quantitative MRI Study.

    PubMed

    Yamasaki, Rosiane; Murano, Emi Z; Gebrim, Eloisa; Hachiya, Adriana; Montagnoli, Arlindo; Behlau, Mara; Tsuji, Domingos

    2017-07-01

    To compare vocal tract (VT) adjustments of dysphonic and non-dysphonic women before and after flexible resonance tube in water exercise (FRTWE) at rest and during phonation using magnetic resonance imaging. Prospective study. Twenty women, aged 20-40 years, 10 dysphonic with vocal nodules (VNG) and 10 controls (CG), underwent four sets of sagittal VT MRI: two pre-FRTWE, at rest and during phonation, and two post-FRTWE, during phonation and at rest. The subjects performed 3 minutes of exercise. Nine parameters at rest and 21 during phonation were performed. Pre-FRTWE, eight significant differences were found, three at rest and five during phonation: at rest - laryngeal vestibule area, distance from epiglottis to pharyngeal posterior wall (PPW) and interarytenoid complex length were smaller in the VNG; during phonation - laryngeal vestibule area, angle between PPW and vocal fold (VF), epiglottis to PPW, and anterior commissure of the larynx to laryngeal posterior wall were smaller in the VNG; tongue area was larger in the VNG. Post-FRTWE, only three significant differences were found, two during phonation and one at rest: during phonation - angle between PPW and VF and the membranous portion of the VF length were smaller in the VNG; at rest - distance from epiglottis to PPW was smaller in the VNG. Results suggest that the habitual VT adjustments of dysphonic and non-dysphonic women are different at rest and during phonation. The FRTWE promoted positive VT changes in the VNG, reducing the intergroup differences. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  2. Vibratory regime classification of infant phonation.

    PubMed

    Buder, Eugene H; Chorna, Lesya B; Oller, D Kimbrough; Robinson, Rebecca B

    2008-09-01

    Infant phonation is highly variable in many respects, including the basic vibratory patterns by which the vocal tissues create acoustic signals. Previous studies have identified the regular occurrence of nonmodal phonation types in normal infant phonation. The glottis is like many oscillating systems that, because of nonlinear relationships among the elements, may vibrate in ways representing the deterministic patterns classified theoretically within the mathematical framework of nonlinear dynamics. The infant's preverbal vocal explorations present such a variety of phonations that it may be possible to find effectively all the classes of vibration predicted by nonlinear dynamic theory. The current report defines acoustic criteria for an important subset of such vibratory regimes, and demonstrates that analysts can be trained to reliably use these criteria for a classification that includes all instances of infant phonation in the recorded corpora. The method is thus internally comprehensive in the sense that all phonations are classified, but it is not exhaustive in the sense that all vocal qualities are thereby represented. Using the methods thus developed, this study also demonstrates that the distributions of these phonation types vary significantly across sessions of recording in the first year of life, suggesting developmental changes. The method of regime classification is thus capable of tracking changes that may be indicative of maturation of the mechanism, the learning of categories of phonatory control, and the possibly varying use of vocalizations across social contexts.

  3. The effect of resonance tubes on glottal contact quotient with and without task instruction: a comparison of trained and untrained voices.

    PubMed

    Gaskill, Christopher S; Quinney, Dana M

    2012-05-01

    Phonation into narrow tubes or straws has been used as a voice training and voice therapy technique and belongs to a group of techniques known as semi-occluded vocal tract exercises. The use of what are called resonance tubes has received renewed attention in the voice research literature, in both theoretical and empirical studies. The assumption is that the partially occluded and lengthened vocal tract alters supraglottal acoustics in such a way as to allow phonation near a lowered first vocal tract formant, which has been suggested as a way to bring about a more efficient glottal closure pattern for sustained oscillation. In this study, two groups of male participants, 10 with no vocal training and 10 with classical vocal training, phonated into a resonance tube for approximately 1 minute. Electroglottography was used to estimate glottal contact quotient (CQ) during spoken /a/ vowels before tube phonation, during tube phonation, and again during spoken /a/ vowels after tube phonation. Half of each group of participants was made to keep pitch and loudness consistent for all phases of the experiment, replicating the method of a previous study by this author. The other half was instructed to practice phonating into the resonance tube before collecting data and was encouraged to find a pitch and loudness combination that maximized ease of phonation and a sense of forward oral resonance. Glottal CQ altered considerably from baseline for almost all participants during tube phonation, with a larger variability than that during vowel production. Small differences in glottal CQ were found as a function of training and instruction, with most participants' CQ increasing during tube phonation. A small post-tube phonation effect was found primarily for the trained and instructed group. Secondary single-subject analyses revealed large intersubject variation, highlighting the highly individualized response to the resonance tube task. Continued study of resonance tubes is recommended, comparing both male and female as well as vocally trained and untrained participants. Future studies should continue to examine systematic variations in task instruction, length of practice, and resonance tube dimensions. Copyright © 2012 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  4. Assessment of canine vocal fold function after injection of a new biomaterial designed to treat phonatory mucosal scarring.

    PubMed

    Karajanagi, Sandeep S; Lopez-Guerra, Gerardo; Park, Hyoungshin; Kobler, James B; Galindo, Marilyn; Aanestad, Jon; Mehta, Daryush D; Kumai, Yoshihiko; Giordano, Nicholas; d'Almeida, Anthony; Heaton, James T; Langer, Robert; Herrera, Victoria L M; Faquin, William; Hillman, Robert E; Zeitels, Steven M

    2011-03-01

    Most cases of irresolvable hoarseness are due to deficiencies in the pliability and volume of the superficial lamina propria of the phonatory mucosa. By using a US Food and Drug Administration-approved polymer, polyethylene glycol (PEG), we created a novel hydrogel (PEG30) and investigated its effects on multiple vocal fold structural and functional parameters. We injected PEG30 unilaterally into 16 normal canine vocal folds with survival times of 1 to 4 months. High-speed videos of vocal fold vibration, induced by intratracheal airflow, and phonation threshold pressures were recorded at 4 time points per subject. Three-dimensional reconstruction analysis of 11.7 T magnetic resonance images and histologic analysis identified 3 cases wherein PEG30 injections were the most superficial, so as to maximally impact vibratory function. These cases were subjected to in-depth analyses. High-speed video analysis of the 3 selected cases showed minimal to no reduction in the maximum vibratory amplitudes of vocal folds injected with PEG30 compared to the non-injected, contralateral vocal fold. All PEG30-injected vocal folds displayed mucosal wave activity with low average phonation threshold pressures. No significant inflammation was observed on microlaryngoscopic examination. Magnetic resonance imaging and histologic analyses revealed time-dependent resorption of the PEG30 hydrogel by phagocytosis with minimal tissue reaction or fibrosis. The PEG30 hydrogel is a promising biocompatible candidate biomaterial to restore form and function to deficient phonatory mucosa, while not mechanically impeding residual endogenous superficial lamina propria.

  5. A meta-analysis of outcomes of hydration intervention on phonation threshold pressure.

    PubMed

    Leydon, Ciara; Wroblewski, Marcin; Eichorn, Naomi; Sivasankar, Mahalakshmi

    2010-11-01

    Vocal fold hydration is purported to promote optimal biomechanical characteristics of vocal fold mucosa, increase efficiency of vocal fold oscillation, and enhance voice quality. The purpose of this work was to determine the magnitude and consistency of the effect of vocal fold hydration on vocal fold function across published clinical studies. We completed a comprehensive meta-analysis of the effects of superficial and systemic vocal fold hydration on phonation threshold pressure (PTP), a measure of efficiency of voice production. We identified 34 studies that examined the effects of hydration on vocal function. Of these studies, 14 examined the effects of hydration on PTP. Nine of these articles met the criteria for inclusion in this analysis. We observed an average effect size of 0.33, indicating that, overall, hydration treatment demonstrated a tendency to reduce PTP. However, this decrease in phonatory effort did not reach significance at the 95% confidence level. The effects of hydration intervention varied considerably across studies (-0.19 to 3.96). We considered that two factors, pitch level of the task and vocal health of participants, may have contributed to this variability in findings. However, our analysis found that these factors could not account for differences in effect size. To understand the variability in outcomes across studies, the role of factors that may impact the effects of hydration, such as the amount, type, and duration of intervention, must be determined. Only then can we obtain data to guide best clinical practice for protecting and rehabilitating vocal function. Copyright © 2010 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  6. Singers' phonation threshold pressure and ratings of self-perceived effort on vocal tasks.

    PubMed

    McHenry, Monica; Evans, Joseph; Powitzky, Eric

    2013-05-01

    This study was designed to determine if singers' self-ratings of vocal effort could predict phonation threshold pressure (PTP). It was hypothesized that effort ratings on the more complex task of singing "Happy Birthday" would best predict PTP. A multiple regression analysis was performed with PTP as the predicted variable and self-ratings on four phonatory tasks as the predictor variables. Participants were 48 undergraduate and graduate students majoring in vocal performance. They produced /pi/ syllable trains as softly as possible for the measurement of PTP. They then rated their self-perceived vocal effort while softly producing the following: (1) sustained "ah" (comfortable, midrange pitch); (2) "ah" glide (chest to head voice); (3) Staccato "ah" in head voice (not falsetto); and (4) Happy Birthday in head voice (not falsetto). No ratings of vocal effort predicted PTP. The lack of correlation between PTP and ratings of Happy Birthday remained when separately evaluating graduate versus undergraduate students or males versus females. Informal evaluation of repeated ratings over time suggested the potential for effective self-monitoring. Students' ratings of self-perceived vocal effort were poor predictors of PTP. This may be because of the use of "effortless" imagery during singing instruction or consistent positive feedback regarding vocal performance. It is possible that self-rating could become an effective tool to predict vocal health if task elicitation instructions were more precise, and the student and voice teacher worked collaboratively to improve self-evaluation. Copyright © 2013 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  7. Effects of Phonation Time and Magnitude Dose on Vocal Fold Epithelial Genes, Barrier Integrity, and Function

    PubMed Central

    Kojima, Tsuyoshi; Valenzuela, Carla V.; Novaleski, Carolyn K.; Van Deusen, Mark; Mitchell, Joshua R.; Garrett, C. Gaelyn; Sivasankar, M. Preeti; Rousseau, Bernard

    2014-01-01

    Objective To investigate the effects of increasing time and magnitude doses of vibration exposure on transcription of the vocal fold's junctional proteins, structural alterations, and functional tissue outcomes. Study Design Animal study. Methods 100 New Zealand White breeder rabbits were studied. Dependent variables were measured in response to increasing time doses (30, 60, or 120 minutes) and magnitude doses (control, modal intensity, and raised intensity) of vibration exposure. Messenger RNA expression of occludin, zonula occluden-1 (ZO-1), E-cadherin, β-catenin, interleukin 1β (IL-1β), cyclooxygenase-2 (COX-2), transforming growth factor β-1 (TGFβ1), and fibronectin were measured. Tissue structural alterations were assessed using transmission electron microscopy (TEM). Transepithelial resistance was used to measure functional tissue outcomes. Results Occludin gene expression was downregulated in vocal folds exposed to 120 minute time doses of raised intensity phonation, relative to control, and modal intensity phonation. ZO-1 gene expression was upregulated following a 120 minute time dose of modal intensity phonation, compared to control, and downregulated after a 120 minute time dose of raised intensity phonation, compared to modal intensity phonation. E-cadherin gene expression was downregulated after a120 minute time dose of raised intensity phonation, compared to control and modal intensity phonation. TEM revealed extensive desquamation of the stratified squamous epithelial cells with increasing time and magnitude doses of vibration exposure. A general observation of lower transepithelial resistance measures was made in tissues exposed to raised intensity phonation, compared to all other groups. Conclusions This study provides evidence of vocal fold tissue responses to varying time and magnitude doses of vibration exposure. Level of Evidence N/A PMID:25073715

  8. Phonation Types in Marathi: An Acoustic Investigation

    ERIC Educational Resources Information Center

    Berkson, Kelly Harper

    2013-01-01

    This dissertation presents a comprehensive instrumental acoustic analysis of phonation type distinctions in Marathi, an Indic language with numerous breathy voiced sonorants and obstruents. Important new facts about breathy voiced sonorants, which are crosslinguistically rare, are established: male and female speakers cue breathy phonation in…

  9. Vibratory Regime Classification of Infant Phonation

    PubMed Central

    Buder, Eugene H.; Chorna, Lesya B.; Oller, D. Kimbrough; Robinson, Rebecca B.

    2008-01-01

    Infant phonation is highly variable in many respects, including the basic vibratory patterns by which the vocal tissues create acoustic signals. Previous studies have identified the regular occurrence of non-modal phonation types in normal infant phonation. The glottis is like many oscillating systems that, because of non-linear relationships among the elements, may vibrate in ways representing the deterministic patterns classified theoretically within the mathematical framework of non-linear dynamics. The infant’s pre-verbal vocal explorations present such a variety of phonations that it may be possible to find effectively all the classes of vibration predicted by non-linear dynamic theory. The current report defines acoustic criteria for an important subset of such vibratory regimes, and demonstrates that analysts can be trained to reliably use these criteria for a classification that includes all instances of infant phonation in the recorded corpora. The method is thus internally comprehensive in the sense that all phonations are classified, but it is not exhaustive in the sense that all vocal qualities are thereby represented. Using the methods thus developed, this study also demonstrates that the distributions of these phonation types vary significantly across sessions of recording in the first year of life, suggesting developmental changes. The method of regime classification is thus capable of tracking changes that may be indicative of maturation of the mechanism, the learning of categories of phonatory control, and the possibly varying use of vocalizations across social contexts. PMID:17509829

  10. In vitro experimental investigation of voice production

    PubMed Central

    Horáčcek, Jaromír; Brücker, Christoph; Becker, Stefan

    2012-01-01

    The process of human phonation involves a complex interaction between the physical domains of structural dynamics, fluid flow, and acoustic sound production and radiation. Given the high degree of nonlinearity of these processes, even small anatomical or physiological disturbances can significantly affect the voice signal. In the worst cases, patients can lose their voice and hence the normal mode of speech communication. To improve medical therapies and surgical techniques it is very important to understand better the physics of the human phonation process. Due to the limited experimental access to the human larynx, alternative strategies, including artificial vocal folds, have been developed. The following review gives an overview of experimental investigations of artificial vocal folds within the last 30 years. The models are sorted into three groups: static models, externally driven models, and self-oscillating models. The focus is on the different models of the human vocal folds and on the ways in which they have been applied. PMID:23181007

  11. Pregnancy and the singing voice: reports from a case study.

    PubMed

    Lã, Filipa Martins Baptista; Sundberg, Johan

    2012-07-01

    Significant changes in body tissues occur during pregnancy; however, literature concerning the effects of pregnancy on the voice is sparse, especially concerning the professional classically trained voice. Hormonal variations and associated bodily changes during pregnancy affect phonatory conditions, such as vocal fold motility and glottal adduction. Longitudinal case study with a semiprofessional classically trained singer. Audio, electrolaryngograph, oral pressure, and air flow signals were recorded once a week during the last 12 weeks of pregnancy, 48 hours after birth and during the following consecutive 11 weeks. Vocal tasks included diminuendo sequences of the syllable /pae/ sung at various pitches, and performing a Lied. Phonation threshold pressures (PTPs) and collision threshold pressures (CTPs), normalized amplitude quotient (NAQ), alpha ratio, and the dominance of the voice source fundamental were determined. Concentrations of sex female steroid hormones were measured on three occasions. A listening test of timbral brightness and vocal fatigue was carried out. Results demonstrated significantly elevated concentrations of estrogen and progesterone during pregnancy, which were considerably reduced after birth. During pregnancy, CTPs and PTPs were high; and NAQ, alpha ratio, and dominance of the voice source fundamental suggested elevated glottal adduction. In addition, a perceptible decrease of vocal brightness was noted. The elevated CTPs and PTPs during pregnancy suggest reduced vocal fold motility and increased glottal adduction. These changes are compatible with expected effects of elevated concentrations of estrogen and progesterone on tissue viscosity and water retention. Copyright © 2012 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  12. Numerical Simulation of the Self-Oscillations of the Vocal Folds and of the Resulting Acoustic Phenomena in the Vocal Tract

    NASA Astrophysics Data System (ADS)

    Švancara, P.; Horáček, J.; Švec, J. G.

    The study presents a three-dimensional (3D) finite element (FE) model of the flow-induced self-oscillation of the human vocal folds in interaction with acoustics of simplified vocal tract models. The 3D vocal tract models of the acoustic spaces shaped for simulation of phonation of Czech vowels [a:], [i:] and [u:] were created by converting the data from the magnetic resonance images (MRI). For modelling of the fluid-structure interaction, explicit coupling scheme with separated solvers for fluid and structure domain was utilized. The FE model comprises vocal folds pretension before starting phonation, large deformations of the vocal fold tissue, vocal-fold collisions, fluid-structure interaction, morphing the fluid mesh according to the vocal-fold motion (Arbitrary Lagrangian-Eulerian approach), unsteady viscous compressible airflow described by the Navier-Stokes equations and airflow separation. The developed FE model enables to study the relationship between flow-induced vibrations of the vocal folds and acoustic wave propagation in the vocal tract and can also be used to simulate for example pathological changes in the vocal fold tissue and their influence on the voice production.

  13. Direct numerical simulation of human phonation

    NASA Astrophysics Data System (ADS)

    Bodony, Daniel; Saurabh, Shakti

    2017-11-01

    The generation and propagation of the human voice in three-dimensions is studied using direct numerical simulation. A full body domain is employed for the purpose of directly computing the sound in the region past the speaker's mouth. The air in the vocal tract is modeled as a compressible and viscous fluid interacting with the elastic vocal folds. The vocal fold tissue material properties are multi-layered, with varying stiffness, and a linear elastic transversely isotropic model is utilized and implemented in a quadratic finite element code. The fluid-solid domains are coupled through a boundary-fitted interface and utilize a Poisson equation-based mesh deformation method. A kinematic constraint based on a specified minimum gap between the vocal folds is applied to prevent collision during glottal closure. Both near VF flow dynamics and far-field acoustics have been studied. A comparison is drawn to current two-dimensional simulations as well as to data from the literature. Near field vocal fold dynamics and glottal flow results are studied and in good agreement with previous three-dimensional phonation studies. Far-field acoustic characteristics, when compared to their two-dimensional counterpart, are shown to be sensitive to the dimensionality. Supported by the National Science Foundation (CAREER Award Number 1150439).

  14. Laryngeal Aerodynamics in Children with Hearing Impairment versus Age and Height Matched Normal Hearing Peers.

    PubMed

    Das, Barshapriya; Chatterjee, Indranil; Kumar, Suman

    2013-01-01

    Lack of proper auditory feedback in hearing-impaired subjects results in functional voice disorder. It is directly related to discoordination of intrinsic and extrinsic laryngeal muscles and disturbed contraction and relaxation of antagonistic muscles. A total of twenty children in the age range of 5-10 years were considered for the study. They were divided into two groups: normal hearing children and hearing aid user children. Results showed a significant difference in the vital capacity, maximum sustained phonation, and fast adduction abduction rate having equal variance for normal and hearing aid user children, respectively, but no significant difference was found in the peak flow value with being statistically significant. A reduced vital capacity in hearing aid user children suggests a limited use of the lung volume for speech production. It may be inferred from the study that the hearing aid user children have poor vocal proficiency which is reflected in their voice. The use of voicing component in hearing impaired subjects is seen due to improper auditory feedback. It was found that there was a significant difference in the vital capacity, maximum sustained phonation (MSP), and fast adduction abduction rate and no significant difference in the peak flow.

  15. Viscosities of implantable biomaterials in vocal fold augmentation surgery.

    PubMed

    Chan, R W; Titze, I R

    1998-05-01

    Vocal fold vibration depends critically on the viscoelasticity of vocal fold tissues. For instance, phonation threshold pressure, a measure of the "ease" of phonation, has been shown to be directly related to the viscosity of the vibrating mucosa. Various implantable biomaterials have been used in vocal fold augmentation surgery, with implantation sites sometimes close to or inside the mucosa. Yet their viscosities or other mechanical properties are seldom known. This study attempts to provide data on viscosities of commonly used phonosurgical biomaterials. Using a parallel-plate rotational rheometer, oscillatory shear experiments were performed on implantable polytetrafluoroethylene (Teflon or Polytef; Mentor Inc., Hingham, MA), collagen (Zyderm; Collagen Corp., Palo Alto, CA), glutaraldehyde crosslinked (GAX) collagen (Phonagel or Zyplast; Collagen Corp.), absorbable gelatin (Gelfoam; Upjohn Co., Kalamazoo, MI), and human abdominal subcutaneous fat. Samples of human vocal fold mucosal tissues were also tested. Under sinusoidal oscillatory shear at 10 Hz and at 37 degrees C, the dynamic viscosity was 116 Pascal-seconds (Pa-s) for polytetrafluoroethylene, 21 Pa-s for gelatin, 8-13 Pa-s for the two types of collagen, 3 Pa-s for fat, and 1 to 3 Pa-s for vocal fold mucosa. Results extrapolated to 100 Hz also show similar differences among the biomaterials, but all values are an order of magnitude lower because of the typical inverse frequency relation (shear thinning effect) for polymeric and biologic materials. The data suggest that the use of fat for vocal fold augmentation may be more conducive to the "ease" of phonation because of its relatively low viscosity, which is closest to physiologic levels. This implication is probably the most relevant in predicting initial outcome of the postoperative voice before there is any significant assimilation (e.g., resorption and fibrosis) of the implanted biomaterial.

  16. Analysis of Voice Impairment in Aphasia after Stroke-Underlying Neuroanatomical Substrates

    ERIC Educational Resources Information Center

    Vukovic, Mile; Sujic, Radmila; Petrovic-Lazic, Mirjana; Miller, Nick; Milutinovic, Dejan; Babac, Snezana; Vukovic, Irena

    2012-01-01

    Phonation is a fundamental feature of human communication. Control of phonation in the context of speech-language disturbances has traditionally been considered a characteristic of lesions to subcortical structures and pathways. Evidence suggests however, that cortical lesions may also implicate phonation. We carried out acoustic and perceptual…

  17. Modifying Electroglottograph-Identified Intervals of Phonation: The Effect on Stuttering.

    ERIC Educational Resources Information Center

    Gow, Merrilyn L.; Ingham, Roger J.

    1992-01-01

    This study, involving an adolescent and adult male with stuttering problems, evaluated modification of the frequency of electroglottograph-measured phonation intervals on stuttering and speech naturalness. Both subjects demonstrated that stuttering could be controlled by modifying the frequency of phonation intervals within short duration ranges,…

  18. Analysis of high-pitched phonation using three-dimensional computed tomography.

    PubMed

    Hiramatsu, Hiroyuki; Tokashiki, Ryoji; Nakamura, Hirokazu; Motohashi, Ray; Sakurai, Eriko; Nomoto, Masaki; Toyomura, Fumimasa; Suzuki, Mamoru

    2012-09-01

    Our aim was to use three-dimensional computed tomography (3DCT) to examine arytenoid cartilage movement during a high-pitched tone task. This was a prospective study. This study included 14 patients with male-to-female gender identity disorder who had undergone 3DCT imaging for surgical simulation between January 2007 and May 2008. First, to prove that the phonation condition was indeed one of the high-pitched phonation, we confirmed the rotational movement of the thyroid cartilage, horizontal gliding movement of the inferior horn, and vocal fold elongation on a high-pitched tone task. Next, we detected the arytenoid cartilage positions of the joint during a comparison of comfortable and high-pitched phonations. We measured the movement direction and movement distance of the arytenoid cartilage. In all cases, the cricothyroid space became narrower (rotation movement), and we observed anterior gliding movement of the inferior horn. In all cases, elongation of the vocal folds by the high-pitched phonation was confirmed and the arytenoid cartilages were displaced both anteriorly and caudally from the position during comfortable phonation by the high-pitched tone task. The arytenoid cartilages did not move posteriorly to elongate the vocal folds during high-pitched phonation. The arytenoid cartilages were pulled anteriorly and moved caudally because of tension associated with vocal fold elongation because of the task of high-pitched phonation. These results suggest that there are no movements at the cricoarytenoid joint that directly control the length of the vocal folds in accordance with pitch. Copyright © 2012 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  19. A Randomized Controlled Trial of Two Semi-Occluded Vocal Tract Voice Therapy Protocols

    PubMed Central

    Hunter, Eric J.; Kirkham, Kimberly; Cox, Karin; Titze, Ingo R.

    2015-01-01

    Purpose Although there is a long history of use of semi-occluded vocal tract gestures in voice therapy, including phonation through thin tubes or straws, the efficacy of phonation through tubes has not been established. This study compares results from a therapy program on the basis of phonation through a flow-resistant tube (FRT) with Vocal Function Exercises (VFE), an established set of exercises that utilize oral semi-occlusions. Method Twenty subjects (16 women, 4 men) with dysphonia and/or vocal fatigue were randomly assigned to 1 of 4 treatment conditions: (a) immediate FRT therapy, (b) immediate VFE therapy, (c) delayed FRT therapy, or (d) delayed VFE therapy. Subjects receiving delayed therapy served as a no-treatment control group. Results Voice Handicap Index (Jacobson et al., 1997) scores showed significant improvement for both treatment groups relative to the no-treatment group. Comparison of the effect sizes suggests FRT therapy is noninferior to VFE in terms of reduction in Voice Handicap Index scores. Significant reductions in Roughness on the Consensus Auditory-Perceptual Evaluation of Voice (Kempster, Gerratt, Verdolini Abbott, Barkmeier-Kraemer, & Hillman, 2009) were found for the FRT subjects, with no other significant voice quality findings. Conclusions VFE and FRT therapy may improve voice quality of life in some individuals with dysphonia. FRT therapy was noninferior to VFE in improving voice quality of life in this study. PMID:25675335

  20. Vertical laryngeal position and oral pressure variations during resonance tube phonation in water and in air. A pilot study.

    PubMed

    Wistbacka, Greta; Sundberg, Johan; Simberg, Susanna

    2016-10-01

    Resonance tube phonation in water (RTPW) is commonly used in voice therapy, particularly in Finland and Sweden. The method is believed to induce a lowering of the vertical laryngeal position (VLP) in phonation as well as variations of the oral pressure, possibly inducing a massage effect. This pilot study presents an attempt to measure VLP and oral pressure in two subjects during RTPW and during phonation with the free tube end in air. VLP is recorded by means of a dual-channel electroglottograph. RTPW was found to lower VLP in the subjects, while it increased during phonation with the tube end in air. RTPW caused an oral pressure modulation with a bubble frequency of 14-22 Hz, depending mainly on the depth of the tube end under the water surface. The results indicate that RTPW lowers the VLP instantly and creates oral pressure variations.

  1. Expiratory and phonation times as measures of disease severity in patients with Multiple Sclerosis. A case-control study.

    PubMed

    Nordio, Sara; Bernitsas, Evanthia; Meneghello, Francesca; Palmer, Katie; Stabile, Maria Rosaria; Dipietro, Laura; Di Stadio, Arianna

    2018-04-21

    Speech disorders are common in patients with Multiple Sclerosis (MS). They can be assessed with several methods, which are however expensive, complex, and not easily accessible to physicians during routine clinic visits. This study aimed at measuring maximum phonation times, maximum expiratory times, and articulation abilities scores in patients with MS compared to healthy subjects and at investigating if any of these parameters could be used as a measure of MS progression. 50 MS patients and 50 gender- and age-matched healthy controls were enrolled in the study. Maximum expiratory times and maximum phonation times were collected from both groups. Articulation abilities were evaluated using the articulation subtest from the Fussi assessment (dysarthria scores). MS patients were evaluated with the Expanded Disability Status Scale (EDSS). Correlations between EDSS scores and maximum expiratory times, maximum phonation times, and dysarthria scores were calculated. EDSS scores of MS patients ranged from 4.5 to 7.5. In MS patients, maximum expiratory times, maximum phonation times, and dysarthria scores were significantly altered compared to healthy controls. Moreover, the EDSS scores were correlated with the maximum expiratory times; the maximum expiratory times were correlated with the maximum phonation times, and the maximum phonation times were correlated with the dysarthria scores. As the expiratory times were significantly correlated with the EDSS scores, they could be used to measure the severity of MS and to monitor its progression. Copyright © 2018 Elsevier B.V. All rights reserved.

  2. Evaluation of palatal plate thickness of maxillary prosthesis on phonation- a comparative clinical study.

    PubMed

    Zakkula, Srujana; B, Sreedevi; Anne, Gopinadh; Manne, Prakash; Bindu O, Swetha Hima; Atla, Jyothi; Deepthi, Sneha; Chaitanya A, Krishna

    2014-04-01

    Prosthodontic treatment involves clinical procedures which influence speech performance directly or indirectly. Prosthetic rehabilitation of missing teeth with partial or complete maxillary removable dentures influences the individual voice characteristics like Phonation, resonance etc. To evaluate the effect of Acrylic palatal plate thickness (1mm-3mm) of maxillary prosthesis on phonation. Twelve subjects were selected randomly between the age group of 20-25 years who have full complement of teeth and have no speech problems. Speech evaluation was done under four experimental conditions i.e. Without any experimental acrylic palatal plate (control), with experimental acrylic palatal plates of thickness 1 mm, 2 mm and 3 mm respectively. The speech material for phonation test consisted of Vowels sounds /a/, /i/, and /o/. Speech analysis to assess phonation was done using digital acoustic analysis (PRAAT software). The obtained results were statistically analyzed by One-way ANOVA and Tukey's multiple post-hoc for comparison of four experimental conditions with respect to different vowel sounds. Mean harmonics to noise ratio (HNR) values obtained for all the Experimental conditions did not show significant difference (p>0.05). In conclusion, an increase in the thickness of the acrylic palatal plate of maxillary prosthesis for about 1 mm - 3mm in complete or partial maxillary removable dentures resulted in no significant effect on phonation of vowel sounds /a/, /i/ and /o/. Increasing the thickness of the palatal plate from 1 mm to 3 mm has not shown any significant effect on the phonation.

  3. Effects of a Semioccluded Vocal Tract on Laryngeal Muscle Activity and Glottal Adduction in a Single Female Subject

    PubMed Central

    Laukkanen, Anne-Maria; Titze, Ingo R.; Hoffman, Henry; Finnegan, Eileen

    2015-01-01

    Voice training exploits semiocclusives, which increase vocal tract interaction with the source. Modeling results suggest that vocal economy (maximum flow declination rate divided by maximum area declination rate, MADR) is improved by matching the glottal and vocal tract impedances. Changes in MADR may be correlated with thyroarytenoid (TA) muscle activity. Here the effects of impedance matching are studied for laryngeal muscle activity and glottal resistance. One female repeated [pa:p:a] before and immediately after (a) phonation into different-sized tubes and (b) voiced bilabial fricative [β:]. To allow estimation of subglottic pressure from the oral pressure, [p] was inserted also in the repetitions of the semiocclusions. Airflow was registered using a flow mask. EMG was registered from TA, cricothyroid (CT) and lateral cricoarytenoid (LCA) muscles. Phonation was simulated using a 7 × 5 × 5 point-mass model of the vocal folds, allowing inputs of simulated laryngeal muscle activation. The variables were TA, CT and LCA activities. Increased vocal tract impedance caused the subject to raise TA activity compared to CT and LCA activities. Computer simulation showed that higher glottal economy and efficiency (oral radiated power divided by aerodynamic power) were obtained with a higher TA/CT ratio when LCA activity was tuned for ideal adduction. PMID:19011306

  4. Hyaluronic acid (with fibronectin) as a bioimplant for the vocal fold mucosa.

    PubMed

    Chan, R W; Titze, I R

    1999-07-01

    To measure the viscoelastic shear properties of hyaluronic acid, with and without fibronectin, and to compare them with those of the human vocal fold mucosa and other phonosurgical biomaterials. Viscoelastic shear properties of various implantable biomaterials (Teflon, gelatin, collagen, fat, hyaluronic acid, and hyaluronic acid with fibronectin) were measured with a parallel-plate rotational rheometer. Elastic and viscous shear properties were quantified as a function of oscillation frequency (0.01-15 Hz) at 37 degrees C. The shear properties of hyaluronic acid were relatively close to those of human vocal fold mucosal tissues reported previously. Hyaluronic acid at specific concentrations (0.5%-1%), with or without fibronectin, was found to exhibit viscous shear properties (viscous shear modulus and dynamic viscosity) similar to those of the average male and female vocal fold mucosa. According to a theory that establishes the effects of tissue shear properties on vocal fold oscillation, phonation threshold pressure (a measure of the ease of phonation) is directly related to the viscous shear modulus of the vibrating vocal fold mucosa. Therefore, our findings suggest that hyaluronic acid, either by itself or mixed with fibronectin, may be a potentially optimal bioimplant for the surgical management of vocal fold mucosal defects and lamina propria deficiencies (e.g., scarring) from a biomechanical standpoint.

  5. Phonation takes precedence over articulation in development as well as evolution of language.

    PubMed

    Oller, D Kimbrough

    2014-12-01

    Early human vocal development is characterized first by emerging control of phonation and later by prosodic and supraglottal articulation. The target article has missed the opportunity to use these facts in the characterization of evolution in language-specific brain mechanisms. Phonation appears to be the initial human-specific brain change for language, and it was presumably a key target of selection in early hominin evolution.

  6. Phonation offset in tracheoesophageal speech.

    PubMed

    Searl, Jeff; Ousley, Teri

    2004-01-01

    Tracheoesophageal (TE) speakers often have difficulty producing the voiced-voiceless distinction. Phonation offset (POff) as a TE speaker transitions from a vowel to a stop consonant may be altered, possibly contributing to listener misperceptions. The purposes of this study were to: (1) compare the duration of POff in TE versus laryngeal speakers, and (2) compare POff between TE productions that were accurately versus inaccurately perceived. Phonation offset and offset duration as a proportion of the stop gap (%POff) were greater for the TE versus the laryngeal samples. There was no difference in POff or %POff when comparing accurately to inaccurately perceived TE samples. Tracheoesophageal speakers may have less ability to halt neoglottal vibration compared to laryngeal speakers' ability to stop glottal vibration. Comparable POff for accurately and inaccurately perceived TE samples suggests that POff may not be a particularly salient acoustic feature to the voicing distinction, at least for stop consonants. (1) As a result of this activity, participants will be able to describe what phonation offset is relative to the voicing distinction. (2) As a result of this activity, participants will be able to describe phonation offset in tracheoesophageal speakers relative to laryngeal speakers. (3) As a result of this activity, participants will be able to describe whether phonation offset in tracheoesophageal speech has perceptual saliency for listeners.

  7. Acoustic characteristics of different target vowels during the laryngeal telescopy.

    PubMed

    Shu, Min-Tsan; Lee, Kuo-Shen; Chang, Chin-Wen; Hsieh, Li-Chun; Yang, Cheng-Chien

    2014-10-01

    The aim of this study was to investigate the acoustic characteristics of target vowels phonated in normal voice persons while performing laryngeal telescopy. The acoustic characteristics are compared to show the extent of possible difference to speculate their impact on phonation function. Thirty-four male subjects aged 20-39 years with normal voice were included in this study. The target vowels were /i/ and /ɛ/. Recording of voice samples was done under natural phonation and during laryngeal telescopy. The acoustic analysis included the parameters of fundamental frequency, jitter, shimmer and noise-to-harmonic ratio. The sound of a target vowel /ɛ/ was perceived identical in more than 90% of the subjects by the examiner and speech language pathologist during the telescopy. Both /i/ and /ɛ/ sounds showed significant difference when compared with the results under natural phonation. There was no significant difference between /i/ and /ɛ/ during the telescopy. The present study showed that change in target vowels during laryngeal telescopy makes no significant difference in the acoustic characteristics. The results may lead to the speculation that the phonation mechanism was not affected significantly by different vowels during the telescopy. This study may suggest that in the principle of comfortable phonation, introduction of the target vowels /i/ and /ɛ/ is practical. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  8. Laryngeal muscle activity in unilateral vocal fold paralysis patients using electromyography and coronal reconstructed images.

    PubMed

    Sanuki, Tetsuji; Yumoto, Eiji; Nishimoto, Kohei; Minoda, Ryosei

    2014-04-01

    To assess laryngeal muscle activity in unilateral vocal fold paralysis (UVFP) patients using laryngeal electromyography (LEMG) and coronal images. Case series with chart review. University hospital. Twenty-one patients diagnosed with UVFP of at least 6 months in duration with paralytic dysphonia, underwent LEMG, phonatory function tests, and coronal imaging. A 4-point scale was used to grade motor unit (MU) recruitment: absent = 4+, greatly decreased = 3+, moderately decreased = 2+, and mildly decreased = 1+. Maximum phonation time (MPT) and mean flow rate (MFR) were employed. Coronal images were assessed for differences in thickness and vertical position of the vocal folds during phonation and inhalation. MU recruitment in thyroarytenoid/lateral cricoarytenoid (TA/LCA) muscle complex results were 1+ for 4 patients, 2+ for 5, 3+ for 6, and 4+ for 6. MPT was positively correlated with MU recruitment. Thinning of the affected fold was evident during phonation in 19 of the 21 subjects. The affected fold was at an equal level with the healthy fold in all 9 subjects with MU recruitment of 1+ and 2+. Eleven of 12 subjects with MU recruitments of 3+ and 4+ showed the affected fold at a higher level than the healthy fold. There was a significant difference between MU recruitment and the vertical position of the affected fold. Synkinetic reinnervation may occur in some cases with UVFP. MU recruitments of TA/LCA muscle complex in UVFP patients may be related to phonatory function and the vertical position of the affected fold.

  9. Aerodynamic and acoustic effects of ventricular gap.

    PubMed

    Alipour, Fariborz; Karnell, Michael

    2014-03-01

    Supraglottic compression is frequently observed in individuals with dysphonia. It is commonly interpreted as an indication of excessive circumlaryngeal muscular tension and ventricular medialization. The purpose of this study was to describe the aerodynamic and acoustic impact of varying ventricular medialization in a canine model. Subglottal air pressure, glottal airflow, electroglottograph, acoustic signals, and high-speed video images were recorded in seven excised canine larynges mounted in vitro for laryngeal vibratory experimentation. The degree of gap between the ventricular folds was adjusted and measured using sutures and weights. Data were recorded during phonation when the ventricular gap was narrow, neutral, and large. Glottal resistance was estimated by measures of subglottal pressure and glottal flow. Glottal resistance increased systematically as ventricular gap became smaller. Wide ventricular gaps were associated with increases in fundamental frequency and decreases in glottal resistance. Sound pressure level did not appear to be impacted by the adjustments in ventricular gap used in this research. Increases in supraglottic compression and associated reduced ventricular width may be observed in a variety of disorders that affect voice quality. Ventricular compression may interact with true vocal fold posture and vibration resulting in predictable changes in aerodynamic, physiological, acoustic, and perceptual measures of phonation. The data from this report supports the theory that narrow ventricular gaps may be associated with disordered phonation. In vitro and in vivo human data are needed to further test this association. Copyright © 2014 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  10. The Effects of Phonation Into Glass, Plastic, and LaxVox Tubes in Singers: A Systematic Review.

    PubMed

    Mendes, Amanda Louize Félix; Dornelas do Carmo, Rodrigo; Dias de Araújo, Aline Menezes Guedes; Paranhos, Luiz Renato; da Mota, Camila Silva Oliveira; Dias, Sheila Schneiberg Valença; Reis, Francisco Prado; Aragão, José Aderval

    2018-05-03

    The present study aimed to perform a systematic literature review to assess the effects of phonation therapy on voice quality and function in singers. The systematic search was performed in February and updated in October 2017. No restriction of year, language, or publication status was applied. The primary electronic databases searched were LILACS, SciELO, PubMed, and Cochrane. Kappa coefficient was used to assess the agreement between examiners in judging article eligibility. The eligible articles were analyzed based on their risk of bias using the tools proposed by the Joanna Briggs Institute. Mendeley Desktop 1.13.3 software package (Mendeley Ltd, London, UK) was used to standardize the references of identified articles. The general sample consisted of 1965 articles screened out of the electronic databases. Two examiners analyzed the sample in the search for eligible articles. The agreement between examiners reached excellent outcomes (kappa coefficient = 0.88). After the selection, phase 6 articles remained eligible. Together, the eligible studies accounted 141 subjects (65 men and 76 women) aged between 18 and 72 years old. Electroglottography was considered as the most common method (83.33%) of assessment of the effects of phonation therapy in singers. The most prevalent exercises within the therapies were phonation into straws and phonation into glass tubes. The phonation into glass tubes immersed in water, straws, and LaxVox tubes promoted positive effects on the voice quality in singers, such as more comfortable phonation, better voice projection, and economy in voice emission. Copyright © 2018 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  11. Evaluation of Palatal Plate Thickness of Maxillary Prosthesis on Phonation- A Comparative Clinical Study

    PubMed Central

    B, Sreedevi; Anne, Gopinadh; Manne, Prakash; Bindu O, Swetha Hima; Atla, Jyothi; Deepthi, Sneha; Chaitanya A, Krishna

    2014-01-01

    Background: Prosthodontic treatment involves clinical procedures which influence speech performance directly or indirectly. Prosthetic rehabilitation of missing teeth with partial or complete maxillary removable dentures influences the individual voice characteristics like Phonation, resonance etc. Aim: To evaluate the effect of Acrylic palatal plate thickness (1mm-3mm) of maxillary prosthesis on phonation. Materials and Methods: Twelve subjects were selected randomly between the age group of 20-25 years who have full complement of teeth and have no speech problems. Speech evaluation was done under four experimental conditions i.e. Without any experimental acrylic palatal plate (control), with experimental acrylic palatal plates of thickness 1 mm, 2 mm and 3 mm respectively. The speech material for phonation test consisted of Vowels sounds /a/, /i/, and /o/. Speech analysis to assess phonation was done using digital acoustic analysis (PRAAT software). The obtained results were statistically analyzed by One-way ANOVA and Tukey’s multiple post-hoc for comparison of four experimental conditions with respect to different vowel sounds. Results: Mean harmonics to noise ratio (HNR) values obtained for all the Experimental conditions did not show significant difference (p>0.05). In conclusion, an increase in the thickness of the acrylic palatal plate of maxillary prosthesis for about 1 mm - 3mm in complete or partial maxillary removable dentures resulted in no significant effect on phonation of vowel sounds /a/, /i/ and /o/. Conclusion: Increasing the thickness of the palatal plate from 1 mm to 3 mm has not shown any significant effect on the phonation. PMID:24959508

  12. PHONATION TAKES PRECEDENCE IN DEVELOPMENT AS WELL AS EVOLUTION OF LANGUAGE

    PubMed Central

    Oller, D. Kimbrough

    2014-01-01

    Early development of vocalization in humans is characterized by emerging control of phonation, rather than of prosody or supraglottal articulation. This fact offers an opportunity to the authors of the target article to enrich their characterization of the evolution of differential brain mechanisms in human and non-human primates. Phonation, I suggest, is the initial target of human-specific brain changes in sound-making capability upon which language is founded. PMID:25514957

  13. Airway Hypersensitivity, Reflux, and Phonation Contribute to Chronic Cough

    PubMed Central

    Francis, David O.; Slaughter, James C.; Ates, Fehmi; Higginbotham, Tina; Stevens, Kristin L.; Garrett, C. Gaelyn; Vaezi, Michael F.

    2015-01-01

    Background & Aims Although chronic cough is a common, its etiology is often elusive, making patient management a challenge. Gastroesophageal reflux and airway hypersensitivity can cause chronic cough. We explored the relationship between reflux, phonation, and cough in patients with idiopathic chronic cough. Methods We performed a blinded, cross-sectional study of non-smoking patients with chronic cough (duration > 8 weeks) refractory to reflux treatment referred to the Digestive Disease Center at Vanderbilt University. All underwent 24-hour acoustic recording concurrently and temporally synchronized with ambulatory pH-impedance monitoring. Cough, phonation, and pH-impedance events were recorded. We evaluated the temporal relationship between cough and phonation or reflux events using Poisson and logistic regression. Results Seventeen patients met the inclusion criteria (88% female; 100% Caucasian; median age, 63 years and interquartile age range, 52–66 years; mean body mass index, 30.6 and interquartile range 27.9–34.0); there were 2048 analyzable coughing events. The probability of subsequent coughing increased with higher burdens of preceding cough, reflux, or phonation. Within the first 15 min after a cough event, the cough event itself was the main trigger of subsequent cough events. After this period, de novo coughing occurred with increases of 1.46-fold in association with reflux alone (95% confidence interval, 1.17–1.82; P<.001) and 1.71-fold in association with the combination of phonation and reflux events. Conclusion Antecedent phonation and reflux increased the rate of cough events in patients with idiopathic chronic cough. Reflux events were more strongly associated with increased rate of coughing. Our findings support the concept that airway hypersensitivity is a cause of chronic cough, and that the vocal folds may be an effector in chronic cough. ClinicalTrials.gov number, NCT01263626. PMID:26492842

  14. Speaking fundamental frequency and phonation time during work and leisure time in vocally healthy preschool teachers measured with a voice accumulator.

    PubMed

    Szabo Portela, Annika; Hammarberg, Britta; Södersten, Maria

    2013-01-01

    More knowledge is needed about preschool teachers' voice use to identify voice behaviours related to work demands that increase the risk for vocal dysfunction. The purpose of this study was to: (1) determine if speaking fundamental frequency (F0) and phonation time differ between work and leisure time and (2) describe variation in F0 and phonation time across the workday in preschool teachers with healthy voices. A portable voice accumulator was used to collect data on F0 and phonation time. Twelve vocally healthy female preschool teachers participated in recordings during both work and leisure time for 2 successive days. Their mean age was 35 years (range 21-53 years). Mean F0 was high during the working day (266 Hz) and decreased significantly after work (p < 0.0001). F0 was high also during leisure time (246 Hz) as compared to reference F0 values for Swedish females based on laboratory recordings. Phonation time at work varied widely among the participants, with an average of 12.0%, and decreased significantly to 5.5% during leisure time (p < 0.0001). Most participants had few opportunities for voice rest during work. Swedish preschool teachers use high levels of F0 and phonation time during work compared to leisure time indicating high vocal load caused by work. To clarify the role of daily voice use in the causation of vocal dysfunction in this profession, recordings over several days are needed. In addition to F0 and phonation time, recordings of voice sound pressure level and background noise level seem important. © 2013 S. Karger AG, Basel.

  15. Quantification of Acute Vocal Fold Epithelial Surface Damage with Increasing Time and Magnitude Doses of Vibration Exposure

    PubMed Central

    Kojima, Tsuyoshi; Van Deusen, Mark; Jerome, W. Gray; Garrett, C. Gaelyn; Sivasankar, M. Preeti; Novaleski, Carolyn K.; Rousseau, Bernard

    2014-01-01

    Because the vocal folds undergo repeated trauma during continuous cycles of vibration, the epithelium is routinely susceptible to damage during phonation. Excessive and prolonged vibration exposure is considered a significant predisposing factor in the development of vocal fold pathology. The purpose of the present study was to quantify the extent of epithelial surface damage following increased time and magnitude doses of vibration exposure using an in vivo rabbit phonation model. Forty-five New Zealand white breeder rabbits were randomized to nine groups and received varying phonation time-doses (30, 60, or 120 minutes) and magnitude-doses (control, modal intensity phonation, or raised intensity phonation) of vibration exposure. Scanning electron microscopy and transmission electron microscopy was used to quantify the degree of epithelial surface damage. Results revealed a significant reduction in microprojection density, microprojection height, and depth of the epithelial surface with increasing time and phonation magnitudes doses, signifying increased epithelial surface damage risk with excessive and prolonged vibration exposure. Destruction to the epithelial cell surface may provide significant insight into the disruption of cell function following prolonged vibration exposure. One important goal achieved in the present study was the quantification of epithelial surface damage using objective imaging criteria. These data provide an important foundation for future studies of long-term tissue recovery from excessive and prolonged vibration exposure. PMID:24626217

  16. Prespeech motor learning in a neural network using reinforcement☆

    PubMed Central

    Warlaumont, Anne S.; Westermann, Gert; Buder, Eugene H.; Oller, D. Kimbrough

    2012-01-01

    Vocal motor development in infancy provides a crucial foundation for language development. Some significant early accomplishments include learning to control the process of phonation (the production of sound at the larynx) and learning to produce the sounds of one’s language. Previous work has shown that social reinforcement shapes the kinds of vocalizations infants produce. We present a neural network model that provides an account of how vocal learning may be guided by reinforcement. The model consists of a self-organizing map that outputs to muscles of a realistic vocalization synthesizer. Vocalizations are spontaneously produced by the network. If a vocalization meets certain acoustic criteria, it is reinforced, and the weights are updated to make similar muscle activations increasingly likely to recur. We ran simulations of the model under various reinforcement criteria and tested the types of vocalizations it produced after learning in the differ-ent conditions. When reinforcement was contingent on the production of phonated (i.e. voiced) sounds, the network’s post learning productions were almost always phonated, whereas when reinforcement was not contingent on phonation, the network’s post-learning productions were almost always not phonated. When reinforcement was contingent on both phonation and proximity to English vowels as opposed to Korean vowels, the model’s post-learning productions were more likely to resemble the English vowels and vice versa. PMID:23275137

  17. Prespeech motor learning in a neural network using reinforcement.

    PubMed

    Warlaumont, Anne S; Westermann, Gert; Buder, Eugene H; Oller, D Kimbrough

    2013-02-01

    Vocal motor development in infancy provides a crucial foundation for language development. Some significant early accomplishments include learning to control the process of phonation (the production of sound at the larynx) and learning to produce the sounds of one's language. Previous work has shown that social reinforcement shapes the kinds of vocalizations infants produce. We present a neural network model that provides an account of how vocal learning may be guided by reinforcement. The model consists of a self-organizing map that outputs to muscles of a realistic vocalization synthesizer. Vocalizations are spontaneously produced by the network. If a vocalization meets certain acoustic criteria, it is reinforced, and the weights are updated to make similar muscle activations increasingly likely to recur. We ran simulations of the model under various reinforcement criteria and tested the types of vocalizations it produced after learning in the different conditions. When reinforcement was contingent on the production of phonated (i.e. voiced) sounds, the network's post-learning productions were almost always phonated, whereas when reinforcement was not contingent on phonation, the network's post-learning productions were almost always not phonated. When reinforcement was contingent on both phonation and proximity to English vowels as opposed to Korean vowels, the model's post-learning productions were more likely to resemble the English vowels and vice versa. Copyright © 2012 Elsevier Ltd. All rights reserved.

  18. Shortening of the front vibrating part of the vocal folds in phonation.

    PubMed

    Pesák, J; Jindra, P

    2005-01-01

    We have tried to make use of the opportunity of repeated observations through the analysis of the recorded movements of the phonating vocal folds by means of the phonating vocal folds through indirect videolaryngostroboscopic technique. The results of our investigation correspond, among others, with Hála and Sovák's diagrammatic description of continual and gradual changes in the vibration of the vocal folds in an uninterrupted sequence of tones of the human voice. In the initial chapter mention has been made of Hála and Honty's works and of Pressmann's work dealing with the described behaviour of the glottis when phonating high-pitched tones. The conclusions analogous to our findings have also been described by means of stereoscopically measuring the length of the phonating vocal folds. In conclusion, by measuring the distances between the anterior commissure and the junction between the membranous part of the vocal fold and vocal process of the arytenoid and the anterior commissure to the posterior nodal point of the vibrating part of the vocal folds we have verified the correctness of the findings published by Czermak, Hála and Honty, Pressmann, and Sovák, who pointed out the phenomenon of the shortening of the front vibrating part of the vocal folds in phonating high-pitched tones of the human voice. Copyright 2005 S. Karger AG, Basel.

  19. Emotions in freely varying and mono-pitched vowels, acoustic and EGG analyses.

    PubMed

    Waaramaa, Teija; Palo, Pertti; Kankare, Elina

    2015-12-01

    Vocal emotions are expressed either by speech or singing. The difference is that in singing the pitch is predetermined while in speech it may vary freely. It was of interest to study whether there were voice quality differences between freely varying and mono-pitched vowels expressed by professional actors. Given their profession, actors have to be able to express emotions both by speech and singing. Electroglottogram and acoustic analyses of emotional utterances embedded in expressions of freely varying vowels [a:], [i:], [u:] (96 samples) and mono-pitched protracted vowels (96 samples) were studied. Contact quotient (CQEGG) was calculated using 35%, 55%, and 80% threshold levels. Three different threshold levels were used in order to evaluate their effects on emotions. Genders were studied separately. The results suggested significant gender differences for CQEGG 80% threshold level. SPL, CQEGG, and F4 were used to convey emotions, but to a lesser degree, when F0 was predetermined. Moreover, females showed fewer significant variations than males. Both genders used more hypofunctional phonation type in mono-pitched utterances than in the expressions with freely varying pitch. The present material warrants further study of the interplay between CQEGG threshold levels and formant frequencies, and listening tests to investigate the perceptual value of the mono-pitched vowels in the communication of emotions.

  20. A comparison of self-oscillating phonation models

    NASA Astrophysics Data System (ADS)

    McPhail, Michael; Campo, Elizabeth; Walters, Gage; Krane, Michael

    2017-11-01

    This talk presents a comparison of self-oscillating models of phonation. The goal is to assess how well synthetic rubber vocal folds reproduce the gross behavior of phonation. Data from molded rubber folds and a variety of excised mammalian larynges were collected from the literature and from the authors' physical model. Gross trends are discussed and a simple scaling is presented that appears to collapse these data. Finally, comparisons between molded rubber folds and excised larynges are highlighted. Acknowledge support from NIH DC R01005642-11.

  1. Computational study of effects of tension imbalance on phonation in a three-dimensional tubular larynx model.

    PubMed

    Xue, Qian; Zheng, Xudong; Mittal, Rajat; Bielamowicz, Steven

    2014-07-01

    The present study explores the use of a continuum-based computational model to investigate the effect of left-right tension imbalance on vocal fold (VF) vibrations and glottal aerodynamics, as well as its implication on phonation. The study allows us to gain new insights into the underlying physical mechanism of irregularities induced by VF tension imbalance associated with unilateral cricothyroid muscle paralysis. A three-dimensional simulation of glottal flow and VF dynamics in a tubular laryngeal model with tension imbalance was conducted by using a coupled flow-structure interaction computational model. Tension imbalance was modeled by reducing by 20% the Young's modulus of one of the VFs, while holding VF length constant. Effects of tension imbalance on vibratory characteristic of the VFs and on the time-varying properties of glottal airflow as well as the aerodynamic energy transfer are comprehensively analyzed. The analysis demonstrates that the continuum-based biomechanical model can provide a good description of phonatory dynamics in tension imbalance conditions. It is found that although 20% tension imbalance does not have noticeable effects on the fundamental frequency, it does lead to a larger glottal flow leakage and asymmetric vibrations of the two VFs. A detailed analysis of the energy transfer suggests that the majority of the energy is consumed by the lateral motion of the VFs and the net energy transferred to the softer fold is less than the one transferred to the normal fold. Copyright © 2014 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  2. [Study of the supra-glottic pressure during partial constriction of the vocal tract].

    PubMed

    Suares, M; Cayrayre, F; Ouaknine, M; de la Brèteque, B Amy; Giovanni, A

    2004-01-01

    Phonation in a small plastic tube 22 cm length and 5 mms diameter (basic exercise of the method of Dr Amy de la Brèteque), is current practice in vocal rehabilitation in France. This work aims to show the effects of this method on the glottic vibration. The hypothesis was that at the time of phonation in the tube with a strong flow as recommended in the method, the vocal cords vibrate without contact. This limits the mechanical trauma at this level. We have analyzed the sound production in a tube in 11 trained and not trained subjects. We simultaneously collected the intra-oral air pressure and the vocal signal which was subjected to a spectral analysis. Spectral analysis confirmed that the signal was produced correctly i.e. with a strong flow and without interruption of the sound less rich in harmonics. We interpreted these results in the light of our preceding works on the glottic vibration and we show that this vocal production was of the sinusoidal type; this implies the absence of physical contact between the vocal cords, which validates our hypothesis. Further works are necessary to better understand the physical relations between the supra-glottic aerodynamic phenomena and the vibratory functioning of the vocal cords and also to analyze the therapeutic potential ofthe method within speech therapy rehabilitation.

  3. Effects of type II thyroplasty on adductor spasmodic dysphonia.

    PubMed

    Sanuki, Tetsuji; Yumoto, Eiji; Minoda, Ryosei; Kodama, Narihiro

    2010-04-01

    Type II thyroplasty, or laryngeal framework surgery, is based on the hypothesis that the effect of adductor spasmodic dysphonia (AdSD) on the voice is due to excessively tight closure of the glottis, hampering phonation. Most of the previous, partially effective treatments have aimed to relieve this tight closure, including recurrent laryngeal nerve section or avulsion, extirpation of the adductor muscle, and botulinum toxin injection, which is currently the most popular. The aim of this study was to assess the effects of type II thyroplasty on aerodynamic and acoustic findings in patients with AdSD. Case series. University hospital. Ten patients with AdSD underwent type II thyroplasty between August 2006 and December 2008. Aerodynamic and acoustic analyses were performed prior to and six months after surgery. Mean flow rates (MFRs) and voice efficiency were evaluated with a phonation analyzer. Jitter, shimmer, the harmonics-to-noise ratio (HNR), standard deviation of the fundamental frequency (SDF0), and degree of voice breaks (DVB) were measured from each subject's longest sustained phonation sample of the vowel /a/. Voice efficiency improved significantly after surgery. No significant difference was found in the MFRs between before and after surgery. Jitter, shimmer, HNR, SDF0, and DVB improved significantly after surgery. Treatment of AdSD with type II thyroplasty significantly improved aerodynamic and acoustic findings. The results of this study suggest that type II thyroplasty provides relief from voice strangulation in patients with AdSD. Copyright 2010 American Academy of Otolaryngology-Head and Neck Surgery Foundation. Published by Mosby, Inc. All rights reserved.

  4. Acoustic characteristics of phonation in "wet voice" conditions.

    PubMed

    Murugappan, Shanmugam; Boyce, Suzanne; Khosla, Sid; Kelchner, Lisa; Gutmark, Ephraim

    2010-04-01

    A perceptible change in phonation characteristics after a swallow has long been considered evidence that food and/or drink material has entered the laryngeal vestibule and is on the surface of the vocal folds as they vibrate. The current paper investigates the acoustic characteristics of phonation when liquid material is present on the vocal folds, using ex vivo porcine larynges as a model. Consistent with instrumental examinations of swallowing disorders or dysphagia in humans, three liquids of different Varibar viscosity ("thin liquid," "nectar," and "honey") were studied at constant volume. The presence of materials on the folds during phonation was generally found to suppress the higher frequency harmonics and generate intermittent additional frequencies in the low and high end of the acoustic spectrum. Perturbation measures showed a higher percentage of jitter and shimmer when liquid material was present on the folds during phonation, but they were unable to differentiate statistically between the three fluid conditions. The finite correlation dimension and positive Lyapunov exponent measures indicated that the presence of materials on the vocal folds excited a chaotic system. Further, these measures were able to reliably differentiate between the baseline and different types of liquid on the vocal folds.

  5. Acoustic characteristics of phonation in “wet voice” conditions

    PubMed Central

    Murugappan, Shanmugam; Boyce, Suzanne; Khosla, Sid; Kelchner, Lisa; Gutmark, Ephraim

    2010-01-01

    A perceptible change in phonation characteristics after a swallow has long been considered evidence that food and∕or drink material has entered the laryngeal vestibule and is on the surface of the vocal folds as they vibrate. The current paper investigates the acoustic characteristics of phonation when liquid material is present on the vocal folds, using ex vivo porcine larynges as a model. Consistent with instrumental examinations of swallowing disorders or dysphagia in humans, three liquids of different Varibar viscosity (“thin liquid,” “nectar,” and “honey”) were studied at constant volume. The presence of materials on the folds during phonation was generally found to suppress the higher frequency harmonics and generate intermittent additional frequencies in the low and high end of the acoustic spectrum. Perturbation measures showed a higher percentage of jitter and shimmer when liquid material was present on the folds during phonation, but they were unable to differentiate statistically between the three fluid conditions. The finite correlation dimension and positive Lyapunov exponent measures indicated that the presence of materials on the vocal folds excited a chaotic system. Further, these measures were able to reliably differentiate between the baseline and different types of liquid on the vocal folds. PMID:20370039

  6. Analysis of the Auditory Feedback and Phonation in Normal Voices.

    PubMed

    Arbeiter, Mareike; Petermann, Simon; Hoppe, Ulrich; Bohr, Christopher; Doellinger, Michael; Ziethe, Anke

    2018-02-01

    The aim of this study was to investigate the auditory feedback mechanisms and voice quality during phonation in response to a spontaneous pitch change in the auditory feedback. Does the pitch shift reflex (PSR) change voice pitch and voice quality? Quantitative and qualitative voice characteristics were analyzed during the PSR. Twenty-eight healthy subjects underwent transnasal high-speed video endoscopy (HSV) at 8000 fps during sustained phonation [a]. While phonating, the subjects heard their sound pitched up for 700 cents (interval of a fifth), lasting 300 milliseconds in their auditory feedback. The electroencephalography (EEG), acoustic voice signal, electroglottography (EGG), and high-speed-videoendoscopy (HSV) were analyzed to compare feedback mechanisms for the pitched and unpitched condition of the phonation paradigm statistically. Furthermore, quantitative and qualitative voice characteristics were analyzed. The PSR was successfully detected within all signals of the experimental tools (EEG, EGG, acoustic voice signal, HSV). A significant increase of the perturbation measures and an increase of the values of the acoustic parameters during the PSR were observed, especially for the audio signal. The auditory feedback mechanism seems not only to control for voice pitch but also for voice quality aspects.

  7. Acoustic and phonatory characterization of the Fado voice.

    PubMed

    Mendes, Ana P; Rodrigues, Aira F; Guerreiro, David Michael

    2013-09-01

    Fado is a Portuguese musical genre, instrumentally accompanied by a Portuguese and an acoustic guitar. Fado singers' voice is perceptually characterized by a low pitch, hoarse, and strained voice. The present research study sketches the acoustic and phonatory profile of the Fado singers' voice. Fifteen Fado singers produced spoken and sung phonatory tasks. For the spoken voice measures, the maximum phonation time and s/z ratio of Fado singers were near the inefficient physiological threshold. Fundamental frequency was higher than that found in nonsingers and lower than that found in Western Classical singers. Jitter and shimmer mean values were higher compared with nonsingers. Harmonic-to-noise ratio (HNR) was similar to the mean values for nonsingers. For the sung voice, jitter was higher compared with Country, Musical Theater, Soul, Jazz, and Western Classical singers and lower than Pop singers. Shimmer mean values were lower than Country, Musical Theater, Pop, Soul, and Jazz singers and higher than Western Classical singers. HNR was similar for Western Classical singers. Maximum phonational frequency range of Fado singers indicated that male and female subjects had a lower range compared with Western Classical singers. Additionally, Fado singers produced vibrato, but singer's formant was rarely produced. These sung voice characteristics could be related with life habits, less/lack of singing training, or could be just a Fado voice characteristic. Copyright © 2013 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  8. Short-Term Effect of Two Semi-Occluded Vocal Tract Training Programs on the Vocal Quality of Future Occupational Voice Users: "Resonant Voice Training Using Nasal Consonants" Versus "Straw Phonation".

    PubMed

    Meerschman, Iris; Van Lierde, Kristiane; Peeters, Karen; Meersman, Eline; Claeys, Sofie; D'haeseleer, Evelien

    2017-09-18

    The purpose of this study was to determine the short-term effect of 2 semi-occluded vocal tract training programs, "resonant voice training using nasal consonants" versus "straw phonation," on the vocal quality of vocally healthy future occupational voice users. A multigroup pretest-posttest randomized control group design was used. Thirty healthy speech-language pathology students with a mean age of 19 years (range: 17-22 years) were randomly assigned into a resonant voice training group (practicing resonant exercises across 6 weeks, n = 10), a straw phonation group (practicing straw phonation across 6 weeks, n = 10), or a control group (receiving no voice training, n = 10). A voice assessment protocol consisting of both subjective (questionnaire, participant's self-report, auditory-perceptual evaluation) and objective (maximum performance task, aerodynamic assessment, voice range profile, acoustic analysis, acoustic voice quality index, dysphonia severity index) measurements and determinations was used to evaluate the participants' voice pre- and posttraining. Groups were compared over time using linear mixed models and generalized linear mixed models. Within-group effects of time were determined using post hoc pairwise comparisons. No significant time × group interactions were found for any of the outcome measures, indicating no differences in evolution over time among the 3 groups. Within-group effects of time showed a significant improvement in dysphonia severity index in the resonant voice training group, and a significant improvement in the intensity range in the straw phonation group. Results suggest that the semi-occluded vocal tract training programs using resonant voice training and straw phonation may have a positive impact on the vocal quality and vocal capacities of future occupational voice users. The resonant voice training caused an improved dysphonia severity index, and the straw phonation training caused an expansion of the intensity range in this population.

  9. Laryngostrobovideography using a flexible laryngofiberscope performed in conjunction with the phonatory examination.

    PubMed

    Fukuda, H; Kawaida, M; Oki, K; Kano, S; Kawasaki, Y; Tsuji, H; Kohno, N

    1990-06-01

    The phonatory examination was performed while monitoring vocal fold vibration by laryngostrobovideography. Vocal fold vibration was video-taped by a laryngostroboscope and flexible laryngofiberscope inserted through the nasal cavity. Simultaneously, the phonatory examination was conducted with a phonation analyzer. The data were entered into a personal microcomputer via an A/D converter and analyzed to obtain the parameters of sound pitch, sound intensity and mean expiratory air flow volume, which were superimposed on the color video monitor screen.

  10. Quantifying the influence of flow asymmetries on glottal sound sources in speech

    NASA Astrophysics Data System (ADS)

    Erath, Byron; Plesniak, Michael

    2008-11-01

    Human speech is made possible by the air flow interaction with the vocal folds. During phonation, asymmetries in the glottal flow field may arise from flow phenomena (e.g. the Coanda effect) as well as from pathological vocal fold motion (e.g. unilateral paralysis). In this study, the effects of flow asymmetries on glottal sound sources were investigated. Dynamically-programmable 7.5 times life-size vocal fold models with 2 degrees-of-freedom (linear and rotational) were constructed to provide a first-order approximation of vocal fold motion. Important parameters (Reynolds, Strouhal, and Euler numbers) were scaled to physiological values. Normal and abnormal vocal fold motions were synthesized, and the velocity field and instantaneous transglottal pressure drop were measured. Variability in the glottal jet trajectory necessitated sorting of the data according to the resulting flow configuration. The dipole sound source is related to the transglottal pressure drop via acoustic analogies. Variations in the transglottal pressure drop (and subsequently the dipole sound source) arising from flow asymmetries are discussed.

  11. FonaDyn - A system for real-time analysis of the electroglottogram, over the voice range

    NASA Astrophysics Data System (ADS)

    Ternström, Sten; Johansson, Dennis; Selamtzis, Andreas

    2018-01-01

    From soft to loud and low to high, the mechanisms of human voice have many degrees of freedom, making it difficult to assess phonation from the acoustic signal alone. FonaDyn is a research tool that combines acoustics with electroglottography (EGG). It characterizes and visualizes in real time the dynamics of EGG waveforms, using statistical clustering of the cycle-synchronous EGG Fourier components, and their sample entropy. The prevalence and stability of different EGG waveshapes are mapped as colored regions into a so-called voice range profile, without needing pre-defined thresholds or categories. With appropriately 'trained' clusters, FonaDyn can classify and map voice regimes. This is of potential scientific, clinical and pedagogical interest.

  12. Preliminary experiments to quantify liquid movement under mimetic vocal fold vibrational forces.

    PubMed

    Titze, Ingo R; Klemuk, Sarah; Lu, Xiaoying

    2014-07-01

    Hydration of vocal fold tissues is essential for self-sustained oscillation. Normal regulatory processes of liquid transport to and from the vocal folds would be expected through the autonomic systems, but the possibility exists that liquid movement may occur locally due to vibrational pressures. Such movement may cause regions of lower or higher concentrations of liquid viscosity and therewith changes in phonation threshold pressure. Hyaluronic acid, a glycosaminoglycan that attracts large quantities of free water, may be a key molecule for transporting or localizing liquids. Some preliminary experiments are reported in which attempts were made to move low-concentration HA liquids with vibration. None of the experiments was conclusive, but collectively they lay some groundwork for future explorations.

  13. Relationship Between the Electroglottographic Signal and Vocal Fold Contact Area.

    PubMed

    Hampala, Vít; Garcia, Maxime; Švec, Jan G; Scherer, Ronald C; Herbst, Christian T

    2016-03-01

    Electroglottography (EGG) is a widely used noninvasive method that purports to measure changes in relative vocal fold contact area (VFCA) during phonation. Despite its broad application, the putative direct relation between the EGG waveform and VFCA has to date only been formally tested in a single study, suggesting an approximately linear relationship. However, in that study, flow-induced vocal fold (VF) vibration was not investigated. A rigorous empirical evaluation of EGG as a measure of VFCA under proper physiological conditions is therefore still needed. Three red deer larynges were phonated in an excised hemilarynx preparation using a conducting glass plate. The time-varying contact between the VF and the glass plate was assessed by high-speed video recordings at 6000 fps, synchronized to the EGG signal. The average differences between the normalized [0, 1] VFCA and EGG waveforms for the three larynges were 0.180 (±0.156), 0.075 (±0.115), and 0.168 (±0.184) in the contacting phase and 0.159 (±0.112), -0.003 (±0.029), and 0.004 (±0.032) in the decontacting phase. Overall, there was a better agreement between VFCA and the EGG waveform in the decontacting phase than in the contacting phase. Disagreements may be caused by nonuniform tissue conductance properties, electrode placement, and electroglottograph hardware circuitry. Pending further research, the EGG waveform may be a reasonable first approximation to change in medial contact area between the VFs during phonation. However, any quantitative and statistical data derived from EGG should be interpreted cautiously, allowing for potential deviations from true VFCA. Copyright © 2016 The Auhors. Published by Elsevier Inc. All rights reserved.

  14. Phonation Quotient in Women: A Measure of Vocal Efficiency Using Three Aerodynamic Instruments.

    PubMed

    Joshi, Ashwini; Watts, Christopher R

    2017-03-01

    The purpose of this study was to examine measures of vital capacity and phonation quotient across three age groups in women using three different aerodynamic instruments representing low-tech and high-tech options. This study has a prospective, repeated measures design. Fifteen women in each age group of 25-39 years, 40-59 years, and 60-79 years were assessed using maximum phonation time and vital capacity obtained from three aerodynamic instruments: a handheld analog windmill type spirometer, a handheld digital spirometer, and the Phonatory Aerodynamic System (PAS), Model 6600. Phonation quotient was calculated using vital capacity from each instrument. Analyses of variance were performed to test for main effects of the instruments and age on vital capacity and derived phonation quotient. Pearson product moment correlation was performed to assess measurement reliability (parallel forms) between the instruments. Regression equations, scatterplots, and coefficients of determination were also calculated. Statistically significant differences were found in vital capacity measures for the digital spirometer compared with the windmill-type spirometer and PAS across age groups. Strong positive correlations were present between all three instruments for both vital capacity and derived phonation quotient measurements. Measurement precision for the digital spirometer was lower than the windmill spirometer compared with the PAS. However, all three instruments had strong measurement reliability. Additionally, age did not have an effect on the measurement across instruments. These results are consistent with previous literature reporting data from male speakers and support the use of low-tech options for measurement of basic aerodynamic variables associated with voice production. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  15. The somatotopy of speech: Phonation and articulation in the human motor cortex

    PubMed Central

    Brown, Steven; Laird, Angela R.; Pfordresher, Peter Q.; Thelen, Sarah M.; Turkeltaub, Peter; Liotti, Mario

    2010-01-01

    A sizable literature on the neuroimaging of speech production has reliably shown activations in the orofacial region of the primary motor cortex. These activations have invariably been interpreted as reflecting “mouth” functioning and thus articulation. We used functional magnetic resonance imaging to compare an overt speech task with tongue movement, lip movement, and vowel phonation. The results showed that the strongest motor activation for speech was the somatotopic larynx area of the motor cortex, thus reflecting the significant contribution of phonation to speech production. In order to analyze further the phonatory component of speech, we performed a voxel-based meta-analysis of neuroimaging studies of syllable-singing (11 studies) and compared the results with a previously-published meta-analysis of oral reading (11 studies), showing again a strong overlap in the larynx motor area. Overall, these findings highlight the under-recognized presence of phonation in imaging studies of speech production, and support the role of the larynx motor cortex in mediating the “melodicity” of speech. PMID:19162389

  16. Numerical analysis of effects of transglottal pressure change on fundamental frequency of phonation.

    PubMed

    Deguchi, Shinji; Matsuzaki, Yuji; Ikeda, Tadashige

    2007-02-01

    In humans, a decrease in transglottal pressure (Pt) causes an increase in the fundamental frequency of phonation (F0) only at a specific voice pitch within the modal register, the mechanism of which remains unclear. In the present study, numerical analyses were performed to investigate the mechanism of the voice pitch-dependent positive change of F0 due to Pt decrease. The airflow and the airway, including the vocal folds, were modeled in terms of mechanics of fluid and structure. Simulations of phonation using the numerical model indicated that Pt affects both the average position and the average amplitude magnitude of vocal fold self-excited oscillation in a non-monotonous manner. This effect results in voice pitch-dependent responses of F0 to Pt decreases, including the positive response of F0 as actually observed in humans. The findings of the present study highlight the importance of considering self-excited oscillation of the vocal folds in elucidation of the phonation mechanism.

  17. The proprioceptive reflex control of the intercostal muscles during their voluntary activation

    PubMed Central

    Davis, J. Newsom; Sears, T. A.

    1970-01-01

    1. A quantitative study has been made of the reflex effects of sudden changes in mechanical load on contracting human intercostal muscles during willed breathing movements involving the chest wall. Averaging techniques were applied to recordings of electromyogram (EMG) and lung volume, and to other parameters of breathing. 2. Load changes were effected for brief periods (10-150 msec) at any predetermined lung volume by sudden connexion of the airway to a pressure source variable between ± 80 cm H2O so that respiratory movement could be either assisted or opposed. In some experiments airway resistance was suddenly reduced by porting from a high to a low resistance external airway. 3. Contracting inspiratory and expiratory intercostal muscles showed a `silent period' with unloading which is attributed to the sudden withdrawal from intercostal motoneurones of monosynaptic excitation of muscle spindle origin. 4. For both inspiratory and expiratory intercostal muscles the typical immediate effect of an increase in load was an inhibitory response (IR) with a latency of about 22 msec followed by an excitatory response (ER) with a latency of 50-60 msec. 5. It was established using brief duration stimuli (< 40 msec) that the IR depended on mechanical events associated with the onset of stimulation, whereas stimuli greater than 40 msec in duration were required to evoke the ER. 6. For constant expiratory flow rate and a constant load, the ER of expiratory intercostal muscles increased as lung volume decreased within the limits set by maximal activation of the motoneurone pool as residual volume was approached. 7. The ER to a constant load increased directly with the expiratory flow rate at which the load applied, also within limits set by maximal activation of the motoneurone pool. 8. For a given load, the ER during phonation was greater than that occurring at a similar expiratory flow rate without phonation when the resistance of the phonating larynx was mimicked by an external airway resistance. 9. It is argued that the IR is due to autogenetic inhibition arising from tendon organs and that the ER is due to autogenetic excitation arising from intercostal muscle spindles. 10. The initial dominance of inhibition in this dual proprioceptive reflex control was not predicted by the servo theory. It is proposed that the reflex pathways subserving autogenetic inhibition are under a centrifugal control which determines in relation to previous experience (learning) the conditions under which autogenetic facilitation is allowed. PMID:5499805

  18. Effect of deep brain stimulation on different speech subsystems in patients with multiple sclerosis.

    PubMed

    Pützer, Manfred; Barry, William John; Moringlane, Jean Richard

    2007-11-01

    The effect of deep brain stimulation on articulation and phonation subsystems in seven patients with multiple sclerosis (MS) was examined. Production parameters in fast syllable-repetitions were defined and measured, and the phonation quality during vowel productions was analyzed. Speech material was recorded for patients (with and without stimulation) and for a group of healthy control speakers. With stimulation, the precision of glottal and supraglottal articulatory gestures is reduced, whereas phonation has a greater tendency to be hyperfunctional in comparison with the healthy control data. Different effects on the two speech subsystems are induced by electrical stimulation of the thalamus in patients with MS.

  19. Biological mechanisms underlying voice changes due to dehydration.

    PubMed

    Verdolini, Katherine; Min, Young; Titze, Ingo R; Lemke, Jon; Brown, Kice; van Mersbergen, Miriam; Jiang, Jack; Fisher, Kim

    2002-04-01

    Four vocally untrained healthy adults, 2 men and 2 women, completed the study. A double-blind placebo-controlled approach was used to administer three treatments to each participant on separate days. Drugs treatments involved a single 60-mg dose of a diuretic, Lasix (LA), on one day, and a single 50-mg dose of an oral antihistamine, diphenhydramine hydrochloride (DH), on another day. A third day involved the administration of a placebo, sugar pills (SP). Critical posttreatment measures were weight (kg), which estimated systemic dehydration, saliva viscosity (centipoise), which estimated secretion dehydration, and phonation threshold pressure (PTP, in cm H2O), at high pitches, which indicated pulmonary drive for phonation. The central experimental question was: Does systemic dehydration, or secretory dehydration, or both, mediate increases in PTP that are known to occur following dehydration treatments? The results showed that LA induced systemic dehydration, as shown by a decrease in total body mass of about 1%. Weight losses were seen during a 1- to 4-hour block following drug administration and persisted for at least 8 hours thereafter. PTPs also increased in that condition, about 23% relative to baseline, but only several hours after whole-body dehydration was initially seen (5-12 hours after drug administration). In contrast, no evidence was seen that DH accomplished either secretory dehydration or PTP shifts. The results indicate that systemic dehydration can mediate PTP increases. The influence of secretory dehydration on PTP is unclear.

  20. On pressure-frequency relations in the excised larynx.

    PubMed

    Alipour, Fariborz; Scherer, Ronald C

    2007-10-01

    The purpose of this study was to find relationships between subglottal pressure (P(s)) and fundamental frequency (F(0)) of phonation in excised larynx models. This included also the relation between F(0) and its rate of change with pressure (dFdP). Canine larynges were prepared and mounted over a tapered tube that supplied pressurized, heated, and humidified air. Glottal adduction was accomplished either by using two-pronged probes to press the arytenoids together or by passing a suture to simulate lateral cricoarytenoid muscle activation. The pressure-frequency relation was obtained through a series of pressure-flow sweep experiments that were conducted for eight excised canine larynges. It was found that, at set adduction and elongation levels, the pressure-frequency relation is nonlinear, and is highly influenced by the adduction and elongation. The results indicated that for the lower phonation mode, the average rate of change of frequency with pressure was 2.9+/-0.7 Hzcm H(2)O, and for the higher mode was 5.3+/-0.5 Hzcm H(2)O for adduction changes and 8.2+/-4.4 Hzcm H(2)O for elongation changes. The results suggest that during speech and singing, the dFdP relationships are taken into account.

  1. Phonation Offset in Tracheoesophageal Speech

    ERIC Educational Resources Information Center

    Searl, Jeff; Ousley, Teri

    2004-01-01

    Tracheoesophageal (TE) speakers often have difficulty producing the voiced-voiceless distinction. Phonation offset (POff) as a TE speaker transitions from a vowel to a stop consonant may be altered, possibly contributing to listener misperceptions. The purposes of this study were to: (1) compare the duration of POff in TE versus laryngeal…

  2. Velocity field measurements in oblique static divergent vocal fold models

    NASA Astrophysics Data System (ADS)

    Erath, Byron

    2005-11-01

    During normal phonation, the vocal fold cycle is characterized by the glottal opening transitioning from a convergent to a divergent passage and then closing before the cycle is repeated. Under ordinary phonatory conditions, both vocal folds, which form the glottal passage, move in phase with each other, creating a time-varying symmetric opening. However, abnormal pathological conditions, such as unilateral paralysis, and polyps, can result in geometrical asymmetries between the vocal folds throughout the phonatory cycle. This study investigates pulsatile flow fields through 7.5 times life-size vocal fold models with included divergence angles of 5 to 30 degrees, and obliquities between the vocal folds of up to 15 degrees. Flow conditions were scaled to match physiological parameters. Data were taken at the anterior posterior mid-plane using phase-averaged Particle Image Velocimetry (PIV). Viscous flow phenomena including the Coanda effect, flow separation points, and jet "flapping" were investigated. The results are compared to previously reported work of flow through symmetric divergent vocal fold models.

  3. Preliminary Results on the Influence of Engineered Artificial Mucus Layer on Phonation

    ERIC Educational Resources Information Center

    Döllinger, Michael; Gröhn, Franziska; Berry, David A.; Eysholdt, Ulrich; Luegmair, Georg

    2014-01-01

    Purpose: Previous studies have confirmed the influence of dehydration and an altered mucus (e.g., due to pathologies) on phonation. However, the underlying reasons for these influences are not fully understood. This study was a preliminary inquiry into the influences of mucus architecture and concentration on vocal fold oscillation. Method: Two…

  4. Comparing Measures of Voice Quality from Sustained Phonation and Continuous Speech

    ERIC Educational Resources Information Center

    Gerratt, Bruce R.; Kreiman, Jody; Garellek, Marc

    2016-01-01

    Purpose: The question of what type of utterance--a sustained vowel or continuous speech--is best for voice quality analysis has been extensively studied but with equivocal results. This study examines whether previously reported differences derive from the articulatory and prosodic factors occurring in continuous speech versus sustained phonation.…

  5. Measurement of Phonated Intervals during Four Fluency-Inducing Conditions

    ERIC Educational Resources Information Center

    Davidow, Jason H.; Bothe, Anne K.; Andreatta, Richard D.; Ye, Jun

    2009-01-01

    Purpose: Previous investigations of persons who stutter have demonstrated changes in vocalization variables during fluency-inducing conditions (FICs). A series of studies has also shown that a reduction in short intervals of phonation, those from 30 to 200 ms, is associated with decreased stuttering. The purpose of this study, therefore, was to…

  6. Aerodynamically and acoustically driven modes of vibration in a physical model of the vocal folds.

    PubMed

    Zhang, Zhaoyan; Neubauer, Juergen; Berry, David A

    2006-11-01

    In a single-layered, isotropic, physical model of the vocal folds, distinct phonation types were identified based on the medial surface dynamics of the vocal fold. For acoustically driven phonation, a single, in-phase, x-10 like eigenmode captured the essential dynamics, and coupled with one of the acoustic resonances of the subglottal tract. Thus, the fundamental frequency appeared to be determined primarily by a subglottal acoustic resonance. In contrast, aerodynamically driven phonation did not naturally appear in the single-layered model, but was facilitated by the introduction of a vertical constraint. For this phonation type, fundamental frequency was relatively independent of the acoustic resonances, and two eigenmodes were required to capture the essential dynamics of the vocal fold, including an out-of-phase x-11 like eigenmode and an in-phase x-10 like eigenmode, as described in earlier theoretical work. The two eigenmodes entrained to the same frequency, and were decoupled from subglottal acoustic resonances. With this independence from the acoustic resonances, vocal fold dynamics appeared to be determined primarily by near-field, fluid-structure interactions.

  7. Weight-Bearing MR Imaging as an Option in the Study of Gravitational Effects on the Vocal Tract of Untrained Subjects in Singing Phonation

    PubMed Central

    Traser, Louisa; Burdumy, Michael; Richter, Bernhard; Vicari, Marco; Echternach, Matthias

    2014-01-01

    Magnetic Resonance Imaging (MRI) of subjects in a supine position can be used to evaluate the configuration of the vocal tract during phonation. However, studies of speech phonation have shown that gravity can affect vocal tract shape and bias measurements. This is one of the reasons that MRI studies of singing phonation have used professionally trained singers as subjects, because they are generally considered to be less affected by the supine body position and environmental distractions. A study of untrained singers might not only contribute to the understanding of intuitive singing function and aid the evaluation of potential hazards for vocal health, but also provide insights into the effect of the supine position on singers in general. In the present study, an open configuration 0.25 T MRI system with a rotatable examination bed was used to study the effect of body position in 20 vocally untrained subjects. The subjects were asked to sing sustained tones in both supine and upright body positions on different pitches and in different register conditions. Morphometric measurements were taken from the acquired images of a sagittal slice depicting the vocal tract. The analysis concerning the vocal tract configuration in the two body positions revealed differences in 5 out of 10 measured articulatory parameters. In the upright position the jaw was less protruded, the uvula was elongated, the larynx more tilted and the tongue was positioned more to the front of the mouth than in the supine position. The findings presented are in agreement with several studies on gravitational effects in speech phonation, but contrast with the results of a previous study on professional singers of our group where only minor differences between upright and supine body posture were observed. The present study demonstrates that imaging of the vocal tract using weight-bearing MR imaging is a feasible tool for the study of sustained phonation in singing for vocally untrained subjects. PMID:25379885

  8. [Mechanism of neoglottic adjustment for voice variation in tracheoesophageal speech].

    PubMed

    Fujimoto, T; Kinishi, M; Mohri, M; Amatsu, M

    1994-06-01

    Over the past 17 years, we have been performing tracheoesophageal (TE) fistulization for voice restoration following total laryngectomy. The purpose of this technique is to divert the exhaled air through the TE fistula into the hypopharynx where the inferior constrictor muscle forms the retropharyngeal prominence on which the neoglottis is located. It is generally accepted that both pulmonary power and laryngeal adjustment control voice frequency and intensity change in laryngeal phonation. Regularity at various pitches and voice intensities was seen in TE phonation, despite laryngeal adjustment being lost. Regular voice production with various pitches and intensities requires a regulatory mechanism for both pulmonary power and the neoglottis. This study was designed to clarify the mechanism of neoglottic adjustment in TE phonation. Ten speakers with TE fistula were subjected to aerodynamic and electrophysiological investigations. Tracheal pressure, fundamental frequency, intensity, and airflow rate were measured for easy phonation, a high-pitched voice, and a loud voice. Resistance and efficiency of the neoglottis were calculated from the data obtained. Electromyograms of the inferior constrictor muscle and tracheal pressure were simultaneously recorded when the pitch or intensity of the voice increased. Six of the ten subjects examined were able to produce a high-pitched voice. Tracheal pressure increased in all six, the airflow rate in four, and neoglottal resistance in five, as compared with the data obtained during easy phonation. Nine of the ten subjects examined were able to produce a loud voice. In all nine, both tracheal pressure and the airflow rate increased as compared with the values measured during easy phonation. Neoglottal resistance had no definite pattern in relation to voice intensity changes. Electrophysiological study demonstrated that the activity of the inferior constrictor muscle increased as tracheal pressure increased so as to raise the pitch or increase the intensity of the voice. These results indicate that the adjustment of neoglottic closure and stiffness produced by the inferior constrictor muscle has the role of varying the frequency or intensity of the voice.

  9. Weight-bearing MR imaging as an option in the study of gravitational effects on the vocal tract of untrained subjects in singing phonation.

    PubMed

    Traser, Louisa; Burdumy, Michael; Richter, Bernhard; Vicari, Marco; Echternach, Matthias

    2014-01-01

    Magnetic Resonance Imaging (MRI) of subjects in a supine position can be used to evaluate the configuration of the vocal tract during phonation. However, studies of speech phonation have shown that gravity can affect vocal tract shape and bias measurements. This is one of the reasons that MRI studies of singing phonation have used professionally trained singers as subjects, because they are generally considered to be less affected by the supine body position and environmental distractions. A study of untrained singers might not only contribute to the understanding of intuitive singing function and aid the evaluation of potential hazards for vocal health, but also provide insights into the effect of the supine position on singers in general. In the present study, an open configuration 0.25 T MRI system with a rotatable examination bed was used to study the effect of body position in 20 vocally untrained subjects. The subjects were asked to sing sustained tones in both supine and upright body positions on different pitches and in different register conditions. Morphometric measurements were taken from the acquired images of a sagittal slice depicting the vocal tract. The analysis concerning the vocal tract configuration in the two body positions revealed differences in 5 out of 10 measured articulatory parameters. In the upright position the jaw was less protruded, the uvula was elongated, the larynx more tilted and the tongue was positioned more to the front of the mouth than in the supine position. The findings presented are in agreement with several studies on gravitational effects in speech phonation, but contrast with the results of a previous study on professional singers of our group where only minor differences between upright and supine body posture were observed. The present study demonstrates that imaging of the vocal tract using weight-bearing MR imaging is a feasible tool for the study of sustained phonation in singing for vocally untrained subjects.

  10. A generalized procedure for analyzing sustained and dynamic vocal fold vibrations from laryngeal high-speed videos using phonovibrograms.

    PubMed

    Unger, Jakob; Schuster, Maria; Hecker, Dietmar J; Schick, Bernhard; Lohscheller, Jörg

    2016-01-01

    This work presents a computer-based approach to analyze the two-dimensional vocal fold dynamics of endoscopic high-speed videos, and constitutes an extension and generalization of a previously proposed wavelet-based procedure. While most approaches aim for analyzing sustained phonation conditions, the proposed method allows for a clinically adequate analysis of both dynamic as well as sustained phonation paradigms. The analysis procedure is based on a spatio-temporal visualization technique, the phonovibrogram, that facilitates the documentation of the visible laryngeal dynamics. From the phonovibrogram, a low-dimensional set of features is computed using a principle component analysis strategy that quantifies the type of vibration patterns, irregularity, lateral symmetry and synchronicity, as a function of time. Two different test bench data sets are used to validate the approach: (I) 150 healthy and pathologic subjects examined during sustained phonation. (II) 20 healthy and pathologic subjects that were examined twice: during sustained phonation and a glissando from a low to a higher fundamental frequency. In order to assess the discriminative power of the extracted features, a Support Vector Machine is trained to distinguish between physiologic and pathologic vibrations. The results for sustained phonation sequences are compared to the previous approach. Finally, the classification performance of the stationary analyzing procedure is compared to the transient analysis of the glissando maneuver. For the first test bench the proposed procedure outperformed the previous approach (proposed feature set: accuracy: 91.3%, sensitivity: 80%, specificity: 97%, previous approach: accuracy: 89.3%, sensitivity: 76%, specificity: 96%). Comparing the classification performance of the second test bench further corroborates that analyzing transient paradigms provides clear additional diagnostic value (glissando maneuver: accuracy: 90%, sensitivity: 100%, specificity: 80%, sustained phonation: accuracy: 75%, sensitivity: 80%, specificity: 70%). The incorporation of parameters describing the temporal evolvement of vocal fold vibration clearly improves the automatic identification of pathologic vibration patterns. Furthermore, incorporating a dynamic phonation paradigm provides additional valuable information about the underlying laryngeal dynamics that cannot be derived from sustained conditions. The proposed generalized approach provides a better overall classification performance than the previous approach, and hence constitutes a new advantageous tool for an improved clinical diagnosis of voice disorders. Copyright © 2015 Elsevier B.V. All rights reserved.

  11. Fluid flow through the larynx channel

    NASA Astrophysics Data System (ADS)

    Miller, J. A.; Pereira, J. C.; Thomas, D. W.

    1988-03-01

    The classic two-mass model of the larynx channel is extended by including the false vocal folds and the laryngeal ventricle. Several glottis profiles are postulated to exist which are the result of the forces applied to the mucus membrane due to intraglottal pressure variation. These profiles constrain the air flow which allows the formation of one or two "venae contractae". The location of these influences the pressure in the glottis and layrngeal ventricle and also gives rise to additional viscous losses as well as losses due to flow enlargement. Sampled waveforms are calculated from the model for volume velocity, glottal area, Reynolds number and fluid forces over the vocal folds for various profiles. Results show that the computed waveforms agree with physiological data [1,2] and that it is not necessary to use any empirical constants to match the simulation results. Also, the onset of phonation is shown to be possible either with abduction or adduction of the vocal folds.

  12. Perturbation and Nonlinear Dynamic Analysis of Acoustic Phonatory Signal in Parkinsonian Patients Receiving Deep Brain Stimulation

    ERIC Educational Resources Information Center

    Lee, Victoria S.; Zhou, Xiao Ping; Rahn, Douglas A., III; Wang, Emily Q.; Jiang, Jack J.

    2008-01-01

    Nineteen PD patients who received deep brain stimulation (DBS), 10 non-surgical (control) PD patients, and 11 non-pathologic age- and gender-matched subjects performed sustained vowel phonations. The following acoustic measures were obtained on the sustained vowel phonations: correlation dimension (D[subscript 2]), percent jitter, percent shimmer,…

  13. Objective definition of rainfall intensity-duration thresholds for the initiation of post-fire debris flows in southern California

    USGS Publications Warehouse

    Staley, Dennis; Kean, Jason W.; Cannon, Susan H.; Schmidt, Kevin M.; Laber, Jayme L.

    2012-01-01

    Rainfall intensity–duration (ID) thresholds are commonly used to predict the temporal occurrence of debris flows and shallow landslides. Typically, thresholds are subjectively defined as the upper limit of peak rainstorm intensities that do not produce debris flows and landslides, or as the lower limit of peak rainstorm intensities that initiate debris flows and landslides. In addition, peak rainstorm intensities are often used to define thresholds, as data regarding the precise timing of debris flows and associated rainfall intensities are usually not available, and rainfall characteristics are often estimated from distant gauging locations. Here, we attempt to improve the performance of existing threshold-based predictions of post-fire debris-flow occurrence by utilizing data on the precise timing of debris flows relative to rainfall intensity, and develop an objective method to define the threshold intensities. We objectively defined the thresholds by maximizing the number of correct predictions of debris flow occurrence while minimizing the rate of both Type I (false positive) and Type II (false negative) errors. We identified that (1) there were statistically significant differences between peak storm and triggering intensities, (2) the objectively defined threshold model presents a better balance between predictive success, false alarms and failed alarms than previous subjectively defined thresholds, (3) thresholds based on measurements of rainfall intensity over shorter duration (≤60 min) are better predictors of post-fire debris-flow initiation than longer duration thresholds, and (4) the objectively defined thresholds were exceeded prior to the recorded time of debris flow at frequencies similar to or better than subjective thresholds. Our findings highlight the need to better constrain the timing and processes of initiation of landslides and debris flows for future threshold studies. In addition, the methods used to define rainfall thresholds in this study represent a computationally simple means of deriving critical values for other studies of nonlinear phenomena characterized by thresholds.

  14. Large-Eddy Simulation of Internal Flow through Human Vocal Folds

    NASA Astrophysics Data System (ADS)

    Lasota, Martin; Šidlof, Petr

    2018-06-01

    The phonatory process occurs when air is expelled from the lungs through the glottis and the pressure drop causes flow-induced oscillations of the vocal folds. The flow fields created in phonation are highly unsteady and the coherent vortex structures are also generated. For accuracy it is essential to compute on humanlike computational domain and appropriate mathematical model. The work deals with numerical simulation of air flow within the space between plicae vocales and plicae vestibulares. In addition to the dynamic width of the rima glottidis, where the sound is generated, there are lateral ventriculus laryngis and sacculus laryngis included in the computational domain as well. The paper presents the results from OpenFOAM which are obtained with a large-eddy simulation using second-order finite volume discretization of incompressible Navier-Stokes equations. Large-eddy simulations with different subgrid scale models are executed on structured mesh. In these cases are used only the subgrid scale models which model turbulence via turbulent viscosity and Boussinesq approximation in subglottal and supraglottal area in larynx.

  15. Control volume analyses of glottal flow using a fully-coupled numerical fluid-structure interaction model

    NASA Astrophysics Data System (ADS)

    Yang, Jubiao; Krane, Michael; Zhang, Lucy

    2013-11-01

    Vocal fold vibrations and the glottal jet are successfully simulated using the modified Immersed Finite Element method (mIFEM), a fully coupled dynamics approach to model fluid-structure interactions. A self-sustained and steady vocal fold vibration is captured given a constant pressure input at the glottal entrance. The flow rates at different axial locations in the glottis are calculated, showing small variations among them due to the vocal fold motion and deformation. To further facilitate the understanding of the phonation process, two control volume analyses, specifically with Bernoulli's equation and Newton's 2nd law, are carried out for the glottal flow based on the simulation results. A generalized Bernoulli's equation is derived to interpret the correlations between the velocity and pressure temporally and spatially along the center line which is a streamline using a half-space model with symmetry boundary condition. A specialized Newton's 2nd law equation is developed and divided into terms to help understand the driving mechanism of the glottal flow.

  16. A Computational Study of Vocal Fold Dehydration During Phonation.

    PubMed

    Wu, Liang; Zhang, Zhaoyan

    2017-12-01

    While vocal fold dehydration is often considered an important factor contributing to vocal fatigue, it still remains unclear whether vocal fold vibration alone is able to induce severe dehydration that has a noticeable effect on phonation and perceived vocal effort. A three-dimensional model was developed to investigate vocal fold systemic dehydration and surface dehydration during phonation. Based on the linear poroelastic theory, the model considered water resupply from blood vessels through the lateral boundary, water movement within the vocal folds, water exchange between the vocal folds and the surface liquid layer through the epithelium, and surface fluid accumulation and discharge to the glottal airway. Parametric studies were conducted to investigate water loss within the vocal folds and from the surface after a 5-min sustained phonation under different permeability and vibration conditions. The results showed that the dehydration generally increased with increasing vibration amplitude, increasing epithelial permeability, and reduced water resupply. With adequate water resupply, a large-amplitude vibration can induce an overall systemic dehydration as high as 3%. The distribution of water loss within the vocal folds was non-uniform, and a local dehydration higher than 5% was observed even under conditions of a low overall systemic dehydration (<1%). Such high level of water loss may severely affect tissue properties, muscular functions, and phonations characteristics. In contrast, water loss of the surface liquid layer was generally an order of magnitude higher than water loss inside the vocal folds, indicating that the surface dehydration level is likely not a good indicator of the systemic dehydration.

  17. Vocal tract and glottal function during and after vocal exercising with resonance tube and straw.

    PubMed

    Guzman, Marco; Laukkanen, Anne-Maria; Krupa, Petr; Horáček, Jaromir; Švec, Jan G; Geneid, Ahmed

    2013-07-01

    The present study aimed to investigate the vocal tract and glottal function during and after phonation into a tube and a stirring straw. A male classically trained singer was assessed. Computerized tomography (CT) was performed when the subject produced [a:] at comfortable speaking pitch, phonated into the resonance tube and when repeating [a:] after the exercise. Similar procedure was performed with a narrow straw after 15 minutes silence. Anatomic distances and area measures were obtained from CT midsagittal and transversal images. Acoustic, perceptual, electroglottographic (EGG), and subglottic pressure measures were also obtained. During and after phonation into the tube or straw, the velum closed the nasal passage better, the larynx position lowered, and hypopharynx area widened. Moreover, the ratio between the inlet of the lower pharynx and the outlet of the epilaryngeal tube became larger during and after tube/straw phonation. Acoustic results revealed a stronger spectral prominence in the singer/speaker's formant cluster region after exercising. Listening test demonstrated better voice quality after straw/tube than before. Contact quotient derived from EGG decreased during both tube and straw and remained lower after exercising. Subglottic pressure increased during straw and remained somewhat higher after it. CT and acoustic results indicated that vocal exercises with increased vocal tract impedance lead to increased vocal efficiency and economy. One of the major changes was the more prominent singer's/speaker's formant cluster. Vocal tract and glottal modifications were more prominent during and after straw exercising compared with tube phonation. Copyright © 2013 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  18. Nonstimulated rabbit phonation model: Cricothyroid approximation.

    PubMed

    Novaleski, Carolyn K; Kojima, Tsuyoshi; Chang, Siyuan; Luo, Haoxiang; Valenzuela, Carla V; Rousseau, Bernard

    2016-07-01

    To describe a nonstimulated in vivo rabbit phonation model using an Isshiki type IV thyroplasty and uninterrupted humidified glottal airflow to produce sustained audible phonation. Prospective animal study. Six New Zealand white breeder rabbits underwent a surgical procedure involving an Isshiki type IV thyroplasty and continuous airflow delivered to the glottis. Phonatory parameters were examined using high-speed laryngeal imaging and acoustic and aerodynamic analysis. Following the procedure, airflow was discontinued, and sutures remained in place to maintain the phonatory glottal configuration for microimaging using a 9.4 Tesla imaging system. High-speed laryngeal imaging revealed sustained vocal fold oscillation throughout the experimental procedure. Analysis of acoustic signals revealed a mean vocal intensity of 61 dB and fundamental frequency of 590 Hz. Aerodynamic analysis revealed a mean airflow rate of 85.91 mL/s and subglottal pressure of 9 cm H2 O. Following the procedure, microimaging revealed that the in vivo phonatory glottal configuration was maintained, providing consistency between the experimental and postexperimental laryngeal geometry. The latter provides a significant milestone that is necessary for geometric reconstruction and to allow for validation of computational simulations against the in vivo rabbit preparation. We demonstrate a nonstimulated in vivo phonation preparation using an Isshiki type IV thyroplasty and continuous humidified glottal airflow in a rabbit animal model. This preparation elicits sustained vocal fold vibration and phonatory measures that are consistent with our laboratory's prior work using direct neuromuscular stimulation for evoked phonation. N/A. Laryngoscope, 126:1589-1594, 2016. © 2016 The American Laryngological, Rhinological and Otological Society, Inc.

  19. Resonance tube phonation in water: High-speed imaging, electroglottographic and oral pressure observations of vocal fold vibrations--a pilot study.

    PubMed

    Granqvist, Svante; Simberg, Susanna; Hertegård, Stellan; Holmqvist, Sofia; Larsson, Hans; Lindestad, Per-Åke; Södersten, Maria; Hammarberg, Britta

    2015-10-01

    Phonation into glass tubes ('resonance tubes'), keeping the free end of the tube in water, has been a frequently used voice therapy method in Finland and more recently also in other countries. The purpose of this exploratory study was to investigate what effects tube phonation with and without water has on the larynx. Two participants were included in the study. The methods used were high-speed imaging, electroglottographic observations of vocal fold vibrations, and measurements of oral pressure during tube phonation. Results showed that the fluctuation in the back pressure during tube phonation in water altered the vocal fold vibrations. In the high-speed imaging, effects were found in the open quotient and amplitude variation of the glottal opening. The open quotient increased with increasing water depth (from 2 cm to 6 cm). A modulation effect by the water bubbles on the vocal fold vibrations was seen both in the high-speed glottal area tracings and in the electroglottography signal. A second experiment revealed that the increased average oral pressure was largely determined by the water depth. The increased open quotient can possibly be explained by an increased abduction of the vocal folds and/or a reduced transglottal pressure. The back pressure of the bubbles also modulates glottal vibrations with a possible 'massage' effect on the vocal folds. This effect and the well-defined average pressure increase due to the known water depth are different from those of other methods using a semi-occluded vocal tract.

  20. Spatiotemporal Quantification of Vocal Fold Vibration After Exposure to Superficial Laryngeal Dehydration: A Preliminary Study.

    PubMed

    Patel, Rita R; Walker, Reuben; Sivasankar, Preeti M

    2016-07-01

    The aim of the study was to evaluate the effects of a superficial laryngeal dehydration challenge on vocal fold vibration in young healthy adults using high-speed video imaging. In this prospective study, the effects of a 60-minute superficial laryngeal dehydration challenge on spatial (speed quotient, amplitude quotient) and temporal measures (jitter percentage, vibratory onset time) of vocal fold vibration and phonation threshold pressure (PTP) were evaluated in 10 (male = 4, female = 6) vocally normal adults (21-29 years). All measures except the vibratory onset time were measured at the 10 (low) and 80 (high) percent level of their pitch range. The vibratory onset time was obtained at habitual pitch and loudness level. Superficial laryngeal dehydration was induced by oral breathing in low ambient humidity. Prechallenge and postchallenge differences were statistically investigated using t tests with Bonferroni correction. The speed quotient at low-pitch phonation significantly decreased after oral breathing of low ambient humidity. Other spatiotemporal measures and PTP at low and high pitch were not significant after challenge. Results from this initial study have implications for the use of high-speed video imaging to detect and quantify the subtle changes in vocal fold vibrations after superficial dehydration in healthy individuals. Preliminary findings indicate that superficial dehydration in healthy individuals results in spatial deviations at low pitch. However, further studies are warranted to identify additional spatiotemporal changes in vocal fold vibration after superficial dehydration in normal and disordered populations. Published by Elsevier Inc.

  1. The Effect of Speech Rate on Stuttering Frequency, Phonated Intervals, Speech Effort, and Speech Naturalness during Chorus Reading

    ERIC Educational Resources Information Center

    Davidow, Jason H.; Ingham, Roger J.

    2013-01-01

    Purpose: This study examined the effect of speech rate on phonated intervals (PIs), in order to test whether a reduction in the frequency of short PIs is an important part of the fluency-inducing mechanism of chorus reading. The influence of speech rate on stuttering frequency, speaker-judged speech effort, and listener-judged naturalness was also…

  2. Biochemical basis of vocal fold mobilization after microflap surgery in a rabbit model.

    PubMed

    Mitchell, Joshua R; Kojima, Tsuyoshi; Wu, Hongmei; Garrett, C Gaelyn; Rousseau, Bernard

    2014-02-01

    To investigate phonation-related extracellular matrix (ECM) changes in the vocal fold lamina propria after microflap surgery using an in vivo rabbit phonation model. Prospective animal study. Twenty-four New Zealand White rabbits were used in this study. Quantitative polymerase chain reaction and immunohistochemistry were used to investigate alterations in vocal fold ECM proinflammatory and profibrotic gene, and protein expression from a control group of animals receiving a microflap without phonation and a separate group of animals receiving experimentally induced phonation on postmicroflap days 0, 3, and 7. IHC demonstrated the highest concentration of CD45 in vocal folds on postoperative day 0. Staining for CD45 was absent by postoperative day 7, with no differences in CD45 staining between groups. Fibronectin gene expression increased significantly on postoperative day 3 in the control and experimentally induced phonation groups, with maximal staining of fibronectin around the microflap incision on postoperative day 7. No alterations in cyclooxygenase-2, interleukin-1β, and transforming growth factor-β1 gene expression were observed between groups. Results of the present study revealed an acute inflammatory response in the vocal fold at the time of microflap (day 0) and up to 3 days post-microflap. By post-operative day 3, staining of CD45 positive cells decreased, with essentially no evidence of inflammation by post-operative day 7. With the end of the acute inflammatory response occurring around day 3, these data may provide support for mobilizing tissue after inflammation has subsided and the process of active tissue remodeling has ensued (days 3-7). N/A. © 2013 The American Laryngological, Rhinological and Otological Society, Inc.

  3. Effects of an artificially lengthened vocal tract on the glottal closed quotient in untrained male voices

    NASA Astrophysics Data System (ADS)

    Gaskill, Christopher Somers

    The use of hard-walled narrow tubes, often called resonance tubes, for the purpose of voice therapy and voice training has a historical precedent and some theoretical support, but the mechanism of any potential benefit from the application of this technique has remained poorly understood. Fifteen vocally untrained male participants produced a series of spoken /a / vowels at a modal pitch and constant loudness, followed by a minute of repeated phonation into a hard-walled glass tube at the same pitch and loudness targets. The tube parameters and tube phonation task criteria were selected according to theoretical calculations predicting an increase in the acoustic load such that phonation would occur under conditions of near-maximum inertive reactance. Following tube phonation, each participant repeated a similar series of spoken /a/ vowels. Electroglottography (EGG) was used to measure the glottal closed quotient (CQ) during each phase of the experiment. A single-subject, multiple-baseline design with direct replication across subjects was used to identify any changes in CQ across the phases of the experiment. Single-subject analysis using the method of Statistical Process Control (SPC) revealed statistically significant changes in CQ during tube phonation, but with no discernable pattern across the 15 participants. These results indicate that the use of resonance tubes can have a distinct effect on glottal closure, but the mechanism behind this change remains unclear. The implication is that vocal loading techniques such as this need to be studied further with specific attention paid to the underlying mechanism of any measured changes in glottal behavior, and especially to the role of instruction and feedback in the therapeutic and pedagogical application of these techniques.

  4. How Stressful Is "Deep Bubbling"?

    PubMed

    Tyrmi, Jaana; Laukkanen, Anne-Maria

    2017-03-01

    Water resistance therapy by phonating through a tube into the water is used to treat dysphonia. Deep submersion (≥10 cm in water, "deep bubbling") is used for hypofunctional voice disorders. Using it with caution is recommended to avoid vocal overloading. This experimental study aimed to investigate how strenuous "deep bubbling" is. Fourteen subjects, half of them with voice training, repeated the syllable [pa:] in comfortable speaking pitch and loudness, loudly, and in strained voice. Thereafter, they phonated a vowel-like sound both in comfortable loudness and loudly into a glass resonance tube immersed 10 cm into the water. Oral pressure, contact quotient (CQ, calculated from electroglottographic signal), and sound pressure level were studied. The peak oral pressure P(oral) during [p] and shuttering of the outer end of the tube was measured to estimate the subglottic pressure P(sub) and the mean P(oral) during vowel portions to enable calculation of transglottic pressure P(trans). Sensations during phonation were reported with an open-ended interview. P(sub) and P(oral) were higher in "deep bubbling" and P(trans) lower than in loud syllable phonation, but the CQ did not differ significantly. Similar results were obtained for the comparison between loud "deep bubbling" and strained phonation, although P(sub) did not differ significantly. Most of the subjects reported "deep bubbling" to be stressful only for respiratory and lip muscles. No big differences were found between trained and untrained subjects. The CQ values suggest that "deep bubbling" may increase vocal fold loading. Further studies should address impact stress during water resistance exercises. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  5. A Detailed Motion Analysis of the Angular Velocity Between the Vocal Folds During Throat Clearing Using High-speed Digital Imaging.

    PubMed

    Iwahashi, Toshihiko; Ogawa, Makoto; Hosokawa, Kiyohito; Kato, Chieri; Inohara, Hidenori

    2016-11-01

    To assess the angular velocity between the vocal folds just before the compression phase of throat clearing (TC) using high-speed digital imaging (HSDI) of the larynx. Twenty normal healthy adults (13 males and seven females) were enrolled in the study. Each participant underwent transnasal laryngo-fiberscopy, and was asked to perform weak/strong TC followed by a comfortable, sustained vowel phonation while recording an HSDI movie (4000 frames/s) of the larynx. Using a motion analysis, the changes in the vocal fold angle and angular velocity during vocal fold adduction were assessed. Subsequently, we calculated the average angular velocities in the ranges of 100-80%, 80-20%, and 20-0% from all of the angular changes. The motion analysis demonstrated that the changes in the angular velocity resulted in polynomial-like and sigmoid curves during TC and vowel phonation, respectively. The angular velocities during weak TC were significantly higher in the 20-0%, 80-20%, and 100-80% regions (in order); the 80-20% angular velocity in vocal fold adduction during phonation was highest. The 20-0% angular velocity during strong TC was more than twofold higher than 20-0% angular velocity during phonation. The present results confirmed that the closing motions of the vocal folds accelerate throughout the precompression closing phase of a TC episode, and decelerate just before the impact between the vocal folds at the onset of phonation, suggesting that the vocal fold velocity generated by TC is sufficient to damage the laryngeal tissues. Copyright © 2016 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  6. Pulse register phonation in Diana monkey alarm calls

    NASA Astrophysics Data System (ADS)

    Riede, Tobias; Zuberbühler, Klaus

    2003-05-01

    The adult male Diana monkeys (Cercopithecus diana) produce predator-specific alarm calls in response to two of their predators, the crowned eagles and the leopards. The acoustic structure of these alarm calls is remarkable for a number of theoretical and empirical reasons. First, although pulsed phonation has been described in a variety of mammalian vocalizations, very little is known about the underlying production mechanism. Second, Diana monkey alarm calls are based almost exclusively on this vocal production mechanism to an extent that has never been documented in mammalian vocal behavior. Finally, the Diana monkeys' pulsed phonation strongly resembles the pulse register in human speech, where fundamental frequency is mainly controlled by subglottal pressure. Here, we report the results of a detailed acoustic analysis to investigate the production mechanism of Diana monkey alarm calls. Within calls, we found a positive correlation between the fundamental frequency and the pulse amplitude, suggesting that both humans and monkeys control fundamental frequency by subglottal pressure. While in humans pulsed phonation is usually considered pathological or artificial, male Diana monkeys rely exclusively on pulsed phonation, suggesting a functional adaptation. Moreover, we were unable to document any nonlinear phenomena, despite the fact that they occur frequently in the vocal repertoire of humans and nonhumans, further suggesting that the very robust Diana monkey pulse production mechanism has evolved for a particular functional purpose. We discuss the implications of these findings for the structural evolution of Diana monkey alarm calls and suggest that the restricted variability in fundamental frequency and robustness of the source signal gave rise to the formant patterns observed in Diana monkey alarm calls, used to convey predator information.

  7. Comparing Chalk With Cheese-The EGG Contact Quotient Is Only a Limited Surrogate of the Closed Quotient.

    PubMed

    Herbst, Christian T; Schutte, Harm K; Bowling, Daniel L; Svec, Jan G

    2017-07-01

    The electroglottographic (EGG) contact quotient (CQegg), an estimate of the relative duration of vocal fold contact per vibratory cycle, is the most commonly used quantitative analysis parameter in EGG. The purpose of this study is to quantify the CQegg's relation to the closed quotient, a measure more directly related to glottal width changes during vocal fold vibration and the respective sound generation events. Thirteen singers (six females) phonated in four extreme phonation types while independently varying the degree of breathiness and vocal register. EGG recordings were complemented by simultaneous videokymographic (VKG) endoscopy, which allows for calculation of the VKG closed quotient (CQvkg). The CQegg was computed with five different algorithms, all used in previous research. All CQegg algorithms produced CQegg values that clearly differed from the respective CQvkg, with standard deviations around 20% of cycle duration. The difference between CQvkg and CQegg was generally greater for phonations with lower CQvkg. The largest differences were found for low-quality EGG signals with a signal-to-noise ratio below 10 dB, typically stemming from phonations with incomplete glottal closure. Disregarding those low-quality signals, we found the best match between CQegg and CQvkg for a CQegg algorithm operating on the first derivative of the EGG signal. These results show that the terms "closed quotient" and "contact quotient" should not be used interchangeably. They relate to different physiological phenomena. Phonations with incomplete glottal closure having an EGG signal-to-noise ratio below 10 dB are not suited for CQegg analysis. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  8. Do Listeners Store in Memory a Speaker's Habitual Utterance-Final Phonation Type?

    PubMed Central

    Bőhm, Tamás; Shattuck-Hufnagel, Stefanie

    2009-01-01

    Earlier studies report systematic differences across speakers in the occurrence of utterance-final irregular phonation; the work reported here investigated whether human listeners remember this speaker-specific information and can access it when necessary (a prerequisite for using this cue in speaker recognition). Listeners personally familiar with the voices of the speakers were presented with pairs of speech samples: one with the original and the other with transformed final phonation type. Asked to select the member of the pair that was closer to the talker's voice, most listeners tended to choose the unmanipulated token (even though they judged them to sound essentially equally natural). This suggests that utterance-final pitch period irregularity is part of the mental representation of individual speaker voices, although this may depend on the individual speaker and listener to some extent. PMID:19776665

  9. Short-Term Effect of Two Semi-Occluded Vocal Tract Training Programs on the Vocal Quality of Future Occupational Voice Users: "Resonant Voice Training Using Nasal Consonants" versus "Straw Phonation"

    ERIC Educational Resources Information Center

    Meerschman, Iris; Van Lierde, Kristiane; Peeters, Karen; Meersman, Eline; Claeys, Sofie; D'haeseleer, Evelien

    2017-01-01

    Purpose: The purpose of this study was to determine the short-term effect of 2 semi-occluded vocal tract training programs, "resonant voice training using nasal consonants" versus "straw phonation," on the vocal quality of vocally healthy future occupational voice users. Method: A multigroup pretest--posttest randomized control…

  10. Mucosal wave characteristics in three voice modes (fry, hiss & overpressure) produced by a female speaker: a preliminary study using stroboscopy, HSDI and analyzed by kymography, P-FFT & Nyquist plots

    NASA Astrophysics Data System (ADS)

    Izdebski, Krzysztof; Ward, Ronald R.; Yan, Yuling

    2012-02-01

    HSDI provides a whole new way to investigate visually intra-laryngeal behavior and posturing during phonation by providing detailed real-time information about laryngeal biomechanics that include observations about mucosal wave, wave motion directionality, glottic area wave form, asymmetry of vibrations within and across vocal folds and contact area of the glottis including posterior commissure closure. These observations are fundamental to our understanding and modeling of both normal and disordered phonation. In this preliminary report we focus on direct HSDI in vivo observations of not only the glottic region, but also on the entire supraglottic laryngeal posturing during fry, breathy/hiss and over-pressured phonation modes produced in a non-pathological settings. Analysis included spatio-temporal vibration patterns of vocal folds, multi-line kymograms, spectral PFFT analysis, and Nyquist spatio-temporal plots. The presented examples reveal that supraglottic contraction assists in prolonged closed phase of the vibratory cycle, and that prolonged closed phase is longest in fry and overpressure and shortest albeit complex in hiss. Hiss also allows for vocal fold vibration despite glottis separation. These findings need to be compared to pathologic phonation representing the three voice modes to derive at better differential diagnosis.

  11. Pitch matching accuracy of trained singers, untrained subjects with talented singing voices, and untrained subjects with nontalented singing voices in conditions of varying feedback.

    PubMed

    Watts, Christopher; Murphy, Jessica; Barnes-Burroughs, Kathryn

    2003-06-01

    At a physiological level, the act of singing involves control and coordination of several systems involved in the production of sound, including respiration, phonation, resonance, and afferent systems used to monitor production. The ability to produce a melodious singing voice (eg, in tune with accurate pitch) is dependent on control over these motor and sensory systems. To test this position, trained singers and untrained subjects with and without expressed singing talent were asked to match pitches of target pure tones. The ability to match pitch reflected the ability to accurately integrate sensory perception with motor planning and execution. Pitch-matching accuracy was measured at the onset of phonation (prephonatory set) before external feedback could be utilized to adjust the voiced source, during phonation when external auditory feedback could be utilized, and during phonation when external auditory feedback was masked. Results revealed trained singers and untrained subjects with singing talent were no different in their pitch-matching abilities when measured before or after external feedback could be utilized. The untrained subjects with singing talent were also significantly more accurate than the trained singers when external auditory feedback was masked. Both groups were significantly more accurate than the untrained subjects without singing talent.

  12. Use of surface electromyography in phonation studies: an integrative review

    PubMed Central

    Balata, Patricia Maria Mendes; Silva, Hilton Justino da; Moraes, Kyvia Juliana Rocha de; Pernambuco, Leandro de Araújo; Moraes, Sílvia Regina Arruda de

    2013-01-01

    Summary Introduction: Surface electromyography has been used to assess the extrinsic laryngeal muscles during chewing and swallowing, but there have been few studies assessing these muscles during phonation. Objective: To investigate the current state of knowledge regarding the use of surface electromyography for evaluation of the electrical activity of the extrinsic muscles of the larynx during phonation by means of an integrative review. Method: We searched for articles and other papers in the PubMed, Medline/Bireme, and Scielo databases that were published between 1980 and 2012, by using the following descriptors: surface electromyography and voice, surface electromyography and phonation, and surface electromyography and dysphonia. The articles were selectedon the basis ofinclusion and exclusion criteria. Data Synthesis: This was carried out with a cross critical matrix. We selected 27 papers,i.e., 24 articles and 3 theses. The studies differed methodologically with regards to sample size and investigation techniques, making it difficult to compare them, but showed differences in electrical activity between the studied groups (dysphonicsubjects, non-dysphonicsubjects, singers, and others). Conclusion: Electromyography has clinical applicability when technical precautions with respect to application and analysis are obeyed. However, it is necessary to adopt a universal system of assessment tasks and related measurement techniques to allow comparisons between studies. PMID:25992030

  13. Spectral identification of sperm whales from Littoral Acoustic Demonstration Center passive acoustic recordings

    NASA Astrophysics Data System (ADS)

    Sidorovskaia, Natalia A.; Richard, Blake; Ioup, George E.; Ioup, Juliette W.

    2005-09-01

    The Littoral Acoustic Demonstration Center (LADC) made a series of passive broadband acoustic recordings in the Gulf of Mexico and Ligurian Sea to study noise and marine mammal phonations. The collected data contain a large amount of various types of sperm whale phonations, such as isolated clicks and communication codas. It was previously reported that the spectrograms of the extracted clicks and codas contain well-defined null patterns that seem to be unique for individuals. The null pattern is formed due to individual features of the sound production organs of an animal. These observations motivated the present studies of adapting human speech identification techniques for deep-diving marine mammal phonations. A three-state trained hidden Markov model (HMM) was used with the phonation spectra of sperm whales. The HHM-algorithm gave 75% accuracy in identifying individuals when it had been initially tested for the acoustic data set correlated with visual observations of sperm whales. A comparison of the identification accuracy based on null-pattern similarity analysis and the HMM-algorithm is presented. The results can establish the foundation for developing an acoustic identification database for sperm whales and possibly other deep-diving marine mammals that would be difficult to observe visually. [Research supported by ONR.

  14. Intensity-duration threshold of rainfall-triggered debris flows in the Wenchuan Earthquake affected area, China

    NASA Astrophysics Data System (ADS)

    Guo, Xiaojun; Cui, Peng; Li, Yong; Ma, Li; Ge, Yonggang; Mahoney, William B.

    2016-01-01

    The Ms 8.0 Wenchuan Earthquake has greatly altered the rainfall threshold for debris flows in the affected areas. This study explores the local intensity-duration (I-D) relationship based on 252 post-earthquake debris flows. It was found that I = 5.25 D-0.76 accounts for more than 98% of the debris flow occurrences with rainfall duration between 1 and 135 h; therefore the curve defines the threshold for debris flows in the study area. This gives much lower thresholds than those proposed by the previous studies, suggesting that the earthquake has greatly decreased the thresholds in the past years. Moreover, the rainfall thresholds appear to increase annually in the period of 2008-2013, and present a logarithmic increasing tendency, indicating that the thresholds will recover in the future decades.

  15. Vocal fold proteoglycans and their influence on biomechanics.

    PubMed

    Gray, S D; Titze, I R; Chan, R; Hammond, T H

    1999-06-01

    To examine the interstitial proteins of the vocal fold and their influence on the biomechanical properties of that tissue. Anatomic study of the lamina propria of human cadaveric vocal folds combined with some viscosity testing. Identification of proteoglycans is performed with histochemical staining. Quantitative analysis is performed using an image analysis system. A rheometer is used for viscosity testing. Three-dimensional rendering program is used for the computer images. Proteoglycans play an important role in tissue biomechanics. Hyaluronic acid is a key molecule that affects viscosity. The proteoglycans of the lamina propria have important biological and biomechanical effects. The role of hyaluronic acid in determining tissue viscosity is emphasized. Viscosity, its effect on phonatory threshold pressure and energy expended due to phonation is discussed. Proteoglycans, particularly hyaluronic acid, play important roles in determining biomechanical properties of tissue oscillation. Future research will likely make these proteins of important therapeutic interest.

  16. Targeted Acoustic Data Processing for Ocean Ecological Studies

    NASA Astrophysics Data System (ADS)

    Sidorovskaia, N.; Li, K.; Tiemann, C.; Ackleh, A. S.; Tang, T.; Ioup, G. E.; Ioup, J. W.

    2015-12-01

    The Gulf of Mexico is home to many species of deep diving marine mammals. In recent years several ecological studies have collected large volumes of Passive Acoustic Monitoring (PAM) data to investigate the effects of anthropogenic activities on protected and endangered marine mammal species. To utilize these data to their fullest potential for abundance estimates and habitat preference studies, automated detection and classification algorithms are needed to extract species acoustic encounters from a continuous stream of data. The species which phonate in overlapping frequency bands represent a particular challenge. This paper analyzes the performance of a newly developed automated detector for the classification of beaked whale clicks in the Northern Gulf of Mexico. Current used beaked whale classification algorithms rely heavily on experienced human operator involvement in manually associating potential events with a particular species of beaked whales. Our detection algorithm is two-stage: the detector is triggered when the species-representative phonation band energy exceeds the baseline detection threshold. Then multiple event attributes (temporal click duration, central frequency, frequency band, frequency sweep rate, Choi-Williams distribution shape indices) are measured. An attribute vector is then used to discriminate among different species of beaked whales present in the Gulf of Mexico and Risso's dolphins which were recognized to mask the detections of beaked whales in the case of widely used energy-band detectors. The detector is applied to the PAM data collected by the Littoral Acoustic Demonstration Center to estimate abundance trends of beaked whales in the vicinity of the 2010 oil spill before and after the disaster. This algorithm will allow automated processing with minimal operator involvement for new and archival PAM data. [The research is supported by a BP/GOMRI 2015-2017 consortium grant.

  17. Reliable jitter and shimmer measurements in voice clinics: the relevance of vowel, gender, vocal intensity, and fundamental frequency effects in a typical clinical task.

    PubMed

    Brockmann, Meike; Drinnan, Michael J; Storck, Claudio; Carding, Paul N

    2011-01-01

    The aims of this study were to examine vowel and gender effects on jitter and shimmer in a typical clinical voice task while correcting for the confounding effects of voice sound pressure level (SPL) and fundamental frequency (F(0)). Furthermore the relative effect sizes of vowel, gender, voice SPL, and F(0) were assessed, and recommendations for clinical measurements were derived. With this cross-sectional single cohort study, 57 healthy adults (28 women, 29 men) aged 20-40 years were investigated. Three phonations of /a/, /o/, and /i/ at "normal" voice loudness were analyzed using Praat (software). The effects of vowel, gender, voice SPL, and F(0) on jitter and shimmer were assessed using descriptive and inferential (analysis of covariance) statistics. The effect sizes were determined with the eta-squared statistic. Vowels, gender, voice SPL, and F(0), each had significant effects either on jitter or on shimmer, or both. Voice SPL was the most important factor, whereas vowel, gender, and F(0) effects were comparatively small. Because men had systematically higher voice SPL, the gender effects on jitter and shimmer were smaller when correcting for SPL and F(0). Surprisingly, in clinical assessments, voice SPL has the single biggest impact on jitter and shimmer. Vowel and gender effects were clinically important, whereas fundamental frequency had a relatively small influence. Phonations at a predefined voice SPL (80 dB minimum) and vowel (/a/) would enhance measurement reliability. Furthermore, gender-specific thresholds applying these guidelines should be established. However, the efficiency of these measures should be verified and tested with patients. Copyright © 2011 The Voice Foundation. All rights reserved.

  18. [Parameters of phoniatric examination of solo vocalists].

    PubMed

    Mitrović, Slobodan; Jović, Rajko; Aleksić, Vesna; Cvejić, Biserka

    2002-01-01

    A phoniatrist analyzes the professional's voice at the beginning of his vocal studies or career but also later, in cases of voice disorder. Phoniatric examination of professional singers must be done according to "all inclusive" protocols of examination. Such protocols must establish the status of basic elements of phonatory system: activator, generator and resonator of voice and articulatory space. All patients requiring phoniatric examination no matter if they are candidates for professional singers, need to provide anamnestic data about their previous problems regarding voice or singing. This examination is necessary and it must include: examination of nose, cavum oris, pharynx, ears and larynx. This analysis is based on evaluation of physiological and pathophysiological manifestations of voice. Determination of musical voice range during phoniatric examination does not intend to make any classification of voice, nor to suggest to vocal teacher what he should count upon from future singers. Musical range can be determined only by a phoniatrist skilled in music or with musical training, but first of all vocal teacher. These methods are used for examination of phonatory function, or laryngeal pathology. They are not invasive and give objective and quantitative information. They include: laryngostroboscopy, spectral analysis of voice (sonography) and fundamental parameters of voice signal (computer program). Articulation is very important for solo singers, because good articulation contributes to qualitative emission of sound and expression of emotions. Tonal-threshold audiometry is performed as a hearing test. They include rhinomanometry, vital capacity measurements, maximal phonation time and phonation quotient. Phoniatric examination is a necessary proceeding which must be performed before admission to the academy of solo singing, and then during singers' education and career. The phoniatric protocol must include a minimal number of parameters, which can be increased if required. All parameters of phoniatric examination must be adequately evaluated by experts.

  19. Rainfall threshold calculation for debris flow early warning in areas with scarcity of data

    NASA Astrophysics Data System (ADS)

    Pan, Hua-Li; Jiang, Yuan-Jun; Wang, Jun; Ou, Guo-Qiang

    2018-05-01

    Debris flows are natural disasters that frequently occur in mountainous areas, usually accompanied by serious loss of lives and properties. One of the most commonly used approaches to mitigate the risk associated with debris flows is the implementation of early warning systems based on well-calibrated rainfall thresholds. However, many mountainous areas have little data regarding rainfall and hazards, especially in debris-flow-forming regions. Therefore, the traditional statistical analysis method that determines the empirical relationship between rainstorms and debris flow events cannot be effectively used to calculate reliable rainfall thresholds in these areas. After the severe Wenchuan earthquake, there were plenty of deposits deposited in the gullies, which resulted in several debris flow events. The triggering rainfall threshold has decreased obviously. To get a reliable and accurate rainfall threshold and improve the accuracy of debris flow early warning, this paper developed a quantitative method, which is suitable for debris flow triggering mechanisms in meizoseismal areas, to identify rainfall threshold for debris flow early warning in areas with a scarcity of data based on the initiation mechanism of hydraulic-driven debris flow. First, we studied the characteristics of the study area, including meteorology, hydrology, topography and physical characteristics of the loose solid materials. Then, the rainfall threshold was calculated by the initiation mechanism of the hydraulic debris flow. The comparison with other models and with alternate configurations demonstrates that the proposed rainfall threshold curve is a function of the antecedent precipitation index (API) and 1 h rainfall. To test the proposed method, we selected the Guojuanyan gully, a typical debris flow valley that during the 2008-2013 period experienced several debris flow events, located in the meizoseismal areas of the Wenchuan earthquake, as a case study. The comparison with other threshold models and configurations shows that the selected approach is the most promising starting point for further studies on debris flow early warning systems in areas with a scarcity of data.

  20. Brain activity related to phonation in young patients with adductor spasmodic dysphonia.

    PubMed

    Kiyuna, Asanori; Maeda, Hiroyuki; Higa, Asano; Shingaki, Kouta; Uehara, Takayuki; Suzuki, Mikio

    2014-06-01

    This study investigated the brain activities during phonation of young patients with adductor spasmodic dysphonia (ADSD) of relatively short disease duration (<10 years). Six subjects with ADSD of short duration (mean age: 24. 3 years; mean disease duration: 41 months) and six healthy controls (mean age: 30.8 years) underwent functional magnetic resonance imaging (fMRI) using a sparse sampling method to identify brain activity during vowel phonation (/i:/). Intragroup and intergroup analyses were performed using statistical parametric mapping software. Areas of activation in the ADSD and control groups were similar to those reported previously for vowel phonation. All of the activated areas were observed bilaterally and symmetrically. Intergroup analysis revealed higher brain activities in the SD group in the auditory-related areas (Brodmann's areas [BA] 40, 41), motor speech areas (BA44, 45), bilateral insula (BA13), bilateral cerebellum, and middle frontal gyrus (BA46). Areas with lower activation were in the left primary sensory area (BA1-3) and bilateral subcortical nucleus (putamen and globus pallidus). The auditory cortical responses observed may reflect that young ADSD patients control their voice by use of the motor speech area, insula, inferior parietal cortex, and cerebellum. Neural activity in the primary sensory area and basal ganglia may affect the voice symptoms of young ADSD patients with short disease duration. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  1. Phonation interval modification and speech performance quality during fluency-inducing conditions by adults who stutter

    PubMed Central

    Ingham, Roger J.; Bothe, Anne K.; Wang, Yuedong; Purkhiser, Krystal; New, Anneliese

    2012-01-01

    Purpose To relate changes in four variables previously defined as characteristic of normally fluent speech to changes in phonatory behavior during oral reading by persons who stutter (PWS) and normally fluent controls under multiple fluency-inducing (FI) conditions. Method Twelve PWS and 12 controls each completed 4 ABA experiments. During A phases, participants read normally. B phases were 4 different FI conditions: auditory masking, chorus reading, whispering, and rhythmic stimulation. Dependent variables were the durations of accelerometer-recorded phonated intervals; self-judged speech effort; and observer-judged stuttering frequency, speech rate, and speech naturalness. The method enabled a systematic replication of Ingham et al. (2009). Results All FI conditions resulted in decreased stuttering and decreases in the number of short phonated intervals, as compared with baseline conditions, but the only FI condition that satisfied all four characteristics of normally fluent speech was chorus reading. Increases in longer phonated intervals were associated with decreased stuttering but also with poorer naturalness and/or increased speech effort. Previous findings concerning the effects of FI conditions on speech naturalness and effort were replicated. Conclusions Measuring all relevant characteristics of normally fluent speech, in the context of treatments that aim to reduce the occurrence of short-duration PIs, may aid the search for an explanation of the nature of stuttering and may also maximize treatment outcomes for adults who stutter. PMID:22365886

  2. Dynamics of temporal variations in phonatory flow.

    PubMed

    Krane, Michael H; Barry, Michael; Wei, Timothy

    2010-07-01

    This paper addresses the dynamic relevance of time variations of phonatory airflow, commonly neglected under the quasisteady phonatory flow assumption. In contrast to previous efforts, which relied on direct measurement of glottal impedance, this work uses spatially and temporally resolved measurements of the velocity field to estimate the unsteady and convective acceleration terms in the unsteady Bernoulli equation. Theoretical considerations suggest that phonatory flow is inherently unsteady when two related conditions apply: (1) that the unsteady and convective accelerations are commensurate, and (2) that the inertia of the glottal jet is non-negligible. Acceleration waveforms, computed from experimental data, show that unsteady and convective accelerations to be the same order of magnitude, throughout the cycle, and that the jet flow contributes significantly to the unsteady acceleration. In the middle of the cycle, however, jet inertia is negligible because the convective and unsteady accelerations nearly offset one another in the jet region. These results, consistent with previous findings treating quasisteady phonatory flow, emphasize that unsteady acceleration cannot be neglected during the final stages of the phonation cycle, during which voice sound power and spectral content are largely determined. Furthermore, glottal jet dynamics must be included in any model of phonatory airflow.

  3. Dynamics of temporal variations in phonatory flow1

    PubMed Central

    Krane, Michael H.; Barry, Michael; Wei, Timothy

    2010-01-01

    This paper addresses the dynamic relevance of time variations of phonatory airflow, commonly neglected under the quasisteady phonatory flow assumption. In contrast to previous efforts, which relied on direct measurement of glottal impedance, this work uses spatially and temporally resolved measurements of the velocity field to estimate the unsteady and convective acceleration terms in the unsteady Bernoulli equation. Theoretical considerations suggest that phonatory flow is inherently unsteady when two related conditions apply: (1) that the unsteady and convective accelerations are commensurate, and (2) that the inertia of the glottal jet is non-negligible. Acceleration waveforms, computed from experimental data, show that unsteady and convective accelerations to be the same order of magnitude, throughout the cycle, and that the jet flow contributes significantly to the unsteady acceleration. In the middle of the cycle, however, jet inertia is negligible because the convective and unsteady accelerations nearly offset one another in the jet region. These results, consistent with previous findings treating quasisteady phonatory flow, emphasize that unsteady acceleration cannot be neglected during the final stages of the phonation cycle, during which voice sound power and spectral content are largely determined. Furthermore, glottal jet dynamics must be included in any model of phonatory airflow. PMID:20649231

  4. Muscular patterns and activation levels of auxiliary breathing muscles and thorax movement in classical singing.

    PubMed

    Pettersen, Viggo

    2005-01-01

    The aim of this paper is to present an overview of the findings in seven studies exploring muscular patterns and muscle activation levels in selected muscles by classical singers. In addition, the relationship of these muscles to thorax (TX) movement was investigated. Loading levels and respiratory phasing of upper trapezius (TR), sternocleidomastoideus (STM) and the scalenes (SC) were investigated in vocalization tasks with variation in vocal loudness and pitch. Further, muscle activity in the posterior neck (PN) was investigated in inhalation and phonation and, finally, TR, intercostal (INT), lateral abdominal (OBL) and anterior abdominal (RC) muscle loading in student and professional singers was examined. Muscle activity was recorded by use of an ambulatory four-channel monitoring system (Physiometer PHY 400, Premed, Norway). TX movement was traced with two strain gauge sensors (RES-117) placed around the upper TX and lower TX. A phasing of upper TR activity to INT and OBL activity was discovered, all muscles supporting the expiration phase. During phonation, TR contributes in the compression of the upper TX, thus serving as an accessory muscle of expiration. TR activity is reduced with short breathing cycles and is mostly inactive in simplified speaking tasks. During phonation, professional opera singers activate the expiratory-phased TR, INT, OBL and RC muscles to higher levels than student singers do. STM and SC show correlated activity patterns during inhalation and phonation by classical singers. During demanding singing, expiratory-phased STM and SC activity peaks produce a counterforce to the compression of upper TX at high pitches. As breathing demands are lowered, STM and SC activity are reduced and attain inspiratory phasing. Substantial muscle activity is observed in PN during inhalation and phonation. EMG biofeedback performed on TR and STM have a secondary effect of lowering EMG activity in PN. (c) 2005 S. Karger AG, Basel

  5. A comparative analysis of whispered and normally phonated speech using an LPC-10 vocoder

    NASA Astrophysics Data System (ADS)

    Wilson, J. B.; Mosko, J. D.

    1985-12-01

    The determination of the performance of an LPC-10 vocoder in the processing of adult male and female whispered and normally phonated connected speech was the focus of this study. The LPC-10 vocoder's analysis of whispered speech compared quite favorably with similar studies which used sound spectrographic processing techniques. Shifting from phonated speech to whispered speech caused a substantial increase in the phonomic formant frequencies and formant bandwidths for both male and female speakers. The data from this study showed no evidence that the LPC-10 vocoder's ability to process voices with pitch extremes and quality extremes was limited in any significant manner. A comparison of the unprocessed natural vowel waveforms and qualities with the synthesized vowel waveforms and qualities revealed almost imperceptible differences. An LPC-10 vocoder's ability to process linguistic and dialectical suprasegmental features such as intonation, rate and stress at low bit rates should be a critical issue of concern for future research.

  6. Modeling measured glottal volume velocity waveforms.

    PubMed

    Verneuil, Andrew; Berry, David A; Kreiman, Jody; Gerratt, Bruce R; Ye, Ming; Berke, Gerald S

    2003-02-01

    The source-filter theory of speech production describes a glottal energy source (volume velocity waveform) that is filtered by the vocal tract and radiates from the mouth as phonation. The characteristics of the volume velocity waveform, the source that drives phonation, have been estimated, but never directly measured at the glottis. To accomplish this measurement, constant temperature anemometer probes were used in an in vivo canine constant pressure model of phonation. A 3-probe array was positioned supraglottically, and an endoscopic camera was positioned subglottically. Simultaneous recordings of airflow velocity (using anemometry) and glottal area (using stroboscopy) were made in 3 animals. Glottal airflow velocities and areas were combined to produce direct measurements of glottal volume velocity waveforms. The anterior and middle parts of the glottis contributed significantly to the volume velocity waveform, with less contribution from the posterior part of the glottis. The measured volume velocity waveforms were successfully fitted to a well-known laryngeal airflow model. A noninvasive measured volume velocity waveform holds promise for future clinical use.

  7. Prediction of spatially explicit rainfall intensity–duration thresholds for post-fire debris-flow generation in the western United States

    USGS Publications Warehouse

    Staley, Dennis M.; Negri, Jacquelyn; Kean, Jason W.; Laber, Jayme L.; Tillery, Anne C.; Youberg, Ann M.

    2017-01-01

    Early warning of post-fire debris-flow occurrence during intense rainfall has traditionally relied upon a library of regionally specific empirical rainfall intensity–duration thresholds. Development of this library and the calculation of rainfall intensity-duration thresholds often require several years of monitoring local rainfall and hydrologic response to rainstorms, a time-consuming approach where results are often only applicable to the specific region where data were collected. Here, we present a new, fully predictive approach that utilizes rainfall, hydrologic response, and readily available geospatial data to predict rainfall intensity–duration thresholds for debris-flow generation in recently burned locations in the western United States. Unlike the traditional approach to defining regional thresholds from historical data, the proposed methodology permits the direct calculation of rainfall intensity–duration thresholds for areas where no such data exist. The thresholds calculated by this method are demonstrated to provide predictions that are of similar accuracy, and in some cases outperform, previously published regional intensity–duration thresholds. The method also provides improved predictions of debris-flow likelihood, which can be incorporated into existing approaches for post-fire debris-flow hazard assessment. Our results also provide guidance for the operational expansion of post-fire debris-flow early warning systems in areas where empirically defined regional rainfall intensity–duration thresholds do not currently exist.

  8. Prediction of spatially explicit rainfall intensity-duration thresholds for post-fire debris-flow generation in the western United States

    NASA Astrophysics Data System (ADS)

    Staley, Dennis M.; Negri, Jacquelyn A.; Kean, Jason W.; Laber, Jayme L.; Tillery, Anne C.; Youberg, Ann M.

    2017-02-01

    Early warning of post-fire debris-flow occurrence during intense rainfall has traditionally relied upon a library of regionally specific empirical rainfall intensity-duration thresholds. Development of this library and the calculation of rainfall intensity-duration thresholds often require several years of monitoring local rainfall and hydrologic response to rainstorms, a time-consuming approach where results are often only applicable to the specific region where data were collected. Here, we present a new, fully predictive approach that utilizes rainfall, hydrologic response, and readily available geospatial data to predict rainfall intensity-duration thresholds for debris-flow generation in recently burned locations in the western United States. Unlike the traditional approach to defining regional thresholds from historical data, the proposed methodology permits the direct calculation of rainfall intensity-duration thresholds for areas where no such data exist. The thresholds calculated by this method are demonstrated to provide predictions that are of similar accuracy, and in some cases outperform, previously published regional intensity-duration thresholds. The method also provides improved predictions of debris-flow likelihood, which can be incorporated into existing approaches for post-fire debris-flow hazard assessment. Our results also provide guidance for the operational expansion of post-fire debris-flow early warning systems in areas where empirically defined regional rainfall intensity-duration thresholds do not currently exist.

  9. Spatio-temporal analysis of irregular vocal fold oscillations: Biphonation due to desynchronization of spatial modes

    NASA Astrophysics Data System (ADS)

    Neubauer, Jürgen; Mergell, Patrick; Eysholdt, Ulrich; Herzel, Hanspeter

    2001-12-01

    This report is on direct observation and modal analysis of irregular spatio-temporal vibration patterns of vocal fold pathologies in vivo. The observed oscillation patterns are described quantitatively with multiline kymograms, spectral analysis, and spatio-temporal plots. The complex spatio-temporal vibration patterns are decomposed by empirical orthogonal functions into independent vibratory modes. It is shown quantitatively that biphonation can be induced either by left-right asymmetry or by desynchronized anterior-posterior vibratory modes, and the term ``AP (anterior-posterior) biphonation'' is introduced. The presented phonation examples show that for normal phonation the first two modes sufficiently explain the glottal dynamics. The spatio-temporal oscillation pattern associated with biphonation due to left-right asymmetry can be explained by the first three modes. Higher-order modes are required to describe the pattern for biphonation induced by anterior-posterior vibrations. Spatial irregularity is quantified by an entropy measure, which is significantly higher for irregular phonation than for normal phonation. Two asymmetry measures are introduced: the left-right asymmetry and the anterior-posterior asymmetry, as the ratios of the fundamental frequencies of left and right vocal fold and of anterior-posterior modes, respectively. These quantities clearly differentiate between left-right biphonation and anterior-posterior biphonation. This paper proposes methods to analyze quantitatively irregular vocal fold contour patterns in vivo and complements previous findings of desynchronization of vibration modes in computer modes and in in vitro experiments.

  10. Lower Vocal Tract Morphologic Adjustments Are Relevant for Voice Timbre in Singing.

    PubMed

    Mainka, Alexander; Poznyakovskiy, Anton; Platzek, Ivan; Fleischer, Mario; Sundberg, Johan; Mürbe, Dirk

    2015-01-01

    The vocal tract shape is crucial to voice production. Its lower part seems particularly relevant for voice timbre. This study analyzes the detailed morphology of parts of the epilaryngeal tube and the hypopharynx for the sustained German vowels /a/, /e/, /i/, /o/, and /u/ by thirteen male singer subjects who were at the beginning of their academic singing studies. Analysis was based on two different phonatory conditions: a natural, speech-like phonation and a singing phonation, like in classical singing. 3D models of the vocal tract were derived from magnetic resonance imaging and compared with long-term average spectrum analysis of audio recordings from the same subjects. Comparison of singing to the speech-like phonation, which served as reference, showed significant adjustments of the lower vocal tract: an average lowering of the larynx by 8 mm and an increase of the hypopharyngeal cross-sectional area (+ 21:9%) and volume (+ 16:8%). Changes in the analyzed epilaryngeal portion of the vocal tract were not significant. Consequently, lower larynx-to-hypopharynx area and volume ratios were found in singing compared to the speech-like phonation. All evaluated measures of the lower vocal tract varied significantly with vowel quality. Acoustically, an increase of high frequency energy in singing correlated with a wider hypopharyngeal area. The findings offer an explanation how classical male singers might succeed in producing a voice timbre with increased high frequency energy, creating a singer`s formant cluster.

  11. Lower Vocal Tract Morphologic Adjustments Are Relevant for Voice Timbre in Singing

    PubMed Central

    Mainka, Alexander; Poznyakovskiy, Anton; Platzek, Ivan; Fleischer, Mario; Sundberg, Johan; Mürbe, Dirk

    2015-01-01

    The vocal tract shape is crucial to voice production. Its lower part seems particularly relevant for voice timbre. This study analyzes the detailed morphology of parts of the epilaryngeal tube and the hypopharynx for the sustained German vowels /a/, /e/, /i/, /o/, and /u/ by thirteen male singer subjects who were at the beginning of their academic singing studies. Analysis was based on two different phonatory conditions: a natural, speech-like phonation and a singing phonation, like in classical singing. 3D models of the vocal tract were derived from magnetic resonance imaging and compared with long-term average spectrum analysis of audio recordings from the same subjects. Comparison of singing to the speech-like phonation, which served as reference, showed significant adjustments of the lower vocal tract: an average lowering of the larynx by 8 mm and an increase of the hypopharyngeal cross-sectional area (+ 21.9%) and volume (+ 16.8%). Changes in the analyzed epilaryngeal portion of the vocal tract were not significant. Consequently, lower larynx-to-hypopharynx area and volume ratios were found in singing compared to the speech-like phonation. All evaluated measures of the lower vocal tract varied significantly with vowel quality. Acoustically, an increase of high frequency energy in singing correlated with a wider hypopharyngeal area. The findings offer an explanation how classical male singers might succeed in producing a voice timbre with increased high frequency energy, creating a singer‘s formant cluster. PMID:26186691

  12. The effects of self-controlled feedback on learning of a "relaxed phonation task".

    PubMed

    Ma, Estella P-M; Yiu, Gigi K-Y; Yiu, Edwin M-L

    2013-11-01

    This study examined the effects of self-controlled feedback paradigm on motor learning of a relaxed phonation task. It investigated whether providing the learner with more control over practice condition has positive influences on the performance and learning of "relaxed phonation" skill. Vocally healthy individuals were randomly assigned into either self-controlled feedback group (SELF) or clinician-controlled feedback group (YOKED). All participants were engaged in a reading aloud task. Throughout the task, their perilaryngeal muscle activities were measured at thyrohyoid (TH) and orofacial (OF) sites using surface electromyography (EMG). The EMG values measured at the TH site were provided to participants as terminal biofeedback. Participants were required to minimize the EMG values. The SELF group received EMG biofeedback whenever they requested it, whereas the YOKED group received the same feedback schedule as chosen by their self-controlled counterparts. The pooled data for all participants revealed that there was a significant reduction of muscle tension across baseline, training, and retention phases. Generalization was shown to reading of untrained passage. Interestingly, significant reduction of muscle tension across training and retention tests was found in the control OF site but not in the target TH site. The results failed to demonstrate significant differences between SELF and YOKED groups. It provided no clear evidence to conclude that self-controlled feedback paradigm was beneficial to learning of relaxed phonation. Copyright © 2013 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  13. Approximating a retarded-advanced differential equation that models human phonation

    NASA Astrophysics Data System (ADS)

    Teodoro, M. Filomena

    2017-11-01

    In [1, 2, 3] we have got the numerical solution of a linear mixed type functional differential equation (MTFDE) introduced initially in [4], considering the autonomous and non-autonomous case by collocation, least squares and finite element methods considering B-splines basis set. The present work introduces a numerical scheme using least squares method (LSM) and Gaussian basis functions to solve numerically a nonlinear mixed type equation with symmetric delay and advance which models human phonation. The preliminary results are promising. We obtain an accuracy comparable with the previous results.

  14. Flow Glottogram and Subglottal Pressure Relationship in Singers and Untrained Voices.

    PubMed

    Sundberg, Johan

    2018-01-01

    This article combines results from three earlier investigations of the glottal voice source during phonation at varying degrees of vocal loudness (1) in five classically trained baritone singers (Sundberg et al., 1999), (2) in 15 female and 14 male untrained voices (Sundberg et al., 2005), and (3) in voices rated as hyperfunctional by an expert panel (Millgård et al., 2015). Voice source data were obtained by inverse filtering. Associated subglottal pressures were estimated from oral pressure during the occlusion for the consonant /p/. Five flow glottogram parameters, (1) maximum flow declination rate (MFDR), (2) peak-to-peak pulse amplitude, (3) level difference between the first and the second harmonics of the voice source, (4) closed quotient, and (5) normalized amplitude quotient, were averaged across the singer subjects and related to associated MFDR values. Strong, quantitative relations, expressed as equations, are found between subglottal pressure and MFDR and between MFDR and each of the other flow glottogram parameters. The values for the untrained voices, as well as those for the voices rated as hyperfunctional, deviate systematically from the values derived from the equations. Copyright © 2018 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  15. Evaluation of Synthetic Self-Oscillating Models of the Vocal Folds

    NASA Astrophysics Data System (ADS)

    Hubler, Elizabeth P.; Weiland, Kelley S.; Hancock, Adrienne B.; Plesniak, Michael W.

    2013-11-01

    Approximately 30% of people will suffer from a voice disorder at some point in their lives. The probability doubles for those who rely heavily on their voice, such as teachers and singers. Synthetic vocal fold (VF) models are fabricated and evaluated experimentally in a vocal tract simulator to replicate physiological conditions. Pressure measurements are acquired along the vocal tract and high-speed images are captured at varying flow rates during VF oscillation to facilitate understanding of the characteristics of healthy and damaged VFs. The images are analyzed using a videokymography line-scan technique that has been used to examine VF motion and mucosal wave dynamics in vivo. Clinically relevant parameters calculated from the volume-velocity output of a circumferentially-vented mask (Rothenberg mask) are compared to patient data. This study integrates speech science with engineering and flow physics to overcome current limitations of synthetic VF models to properly replicate normal phonation in order to advance the understanding of resulting flow features, progression of pathological conditions, and medical techniques. Supported by the GW Institute for Biomedical Engineering (GWIBE) and GW Center for Biomimetics and Bioinspired Engineering (COBRE).

  16. Neck Circumference and Vocal Parameters in Women Before and After Bariatric Surgery.

    PubMed

    de Souza, Lourdes Bernadete Rocha; Pernambuco, Leandro de Araújo; dos Santos, Marquiony Marques; Pereira, Rayane Medeiros

    2016-03-01

    Morbidly obese patients may suffer from vocal disorders, as vocal production is directly related to the volume of the vocal tract, and the large-scale accumulation of fat in this region may interfere with voice production. The aim of this study was to analyze the neck circumference, fundamental frequency, and maximum phonation time of a group of morbidly obese women before and after bariatric surgery. An observational, longitudinal, and descriptive study was performed with patients of the Obesity and Related Diseases Surgery Unit of a university hospital. A total of 21 morbidly obese women aged 28-68 years, with a mean age of 41.33 years, participated in the study. Neck circumference was measured using a tape measure. To obtain fundamental frequency values, the patient was asked to produce the vowel [a] at normal intensity and pitch for an average period of 3 s. After recording, the participants were asked to produce the sustained vowels [a], [i], and [u] at normal intensity and pitch, with a stopwatch used to measure maximum phonation time. Eight months after surgery, patients were reassessed using the same data collecting procedures as were carried out prior to surgery. After surgery, there was an increase in the average value of fundamental frequency and maximum phonation time for all the vowels and a reduction in neck circumference. The differences were statistically significant. Weight reduction and a consequent decrease in neck circumference affected the changes in maximum phonation time and fundamental frequency values in the voices of these patients, after weight loss.

  17. Computerized Tomography Measures During and After Artificial Lengthening of the Vocal Tract in Subjects With Voice Disorders.

    PubMed

    Guzman, Marco; Miranda, Gonzalo; Olavarria, Christian; Madrid, Sofia; Muñoz, Daniel; Leiva, Miguel; Lopez, Lorena; Bortnem, Cori

    2017-01-01

    The present study aimed to observe the effect of two types of tubes on vocal tract bidimensional and tridimensional images. Ten participants with hyperfunctional dysphonia were included. Computerized tomography was performed during production of sustained [a:], followed by sustained phonation into a drinking straw, and then repetition of sustained [a:]. A similar procedure was performed with a stirring straw after 15 minutes of vocal rest. Anatomic distances and area measures were obtained from computerized tomography midsagittal and transversal images. Vocal tract total volume was also calculated. During tube phonation, increases were measured in the vertical length of the vocal tract, oropharyngeal area, hypopharyngeal area, outlet of the epilaryngeal tube, and inlet to the lower pharynx. Also, the larynx was lower, and more closure was noted between the velum and the nasal passage. Tube phonation causes an increased total vocal tract volume, mostly because of the increased cross-sectional areas in the pharyngeal region. This change is more prominent when the tube offers more airflow resistance (stirring straw) compared with less airflow resistance (drinking straw). Based on our data and previous studies, it seems that vocal tract changes are not dependent on the voice condition (vocally trained, untrained, or disordered voices), but on the exercise itself and the type of instructions given to subjects. Tube phonation is a good option to reach therapeutic goals (eg, wide pharynx and low larynx) without giving biomechanical instructions, but only asking patients to feel easy voice and vibratory sensations. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  18. Superimposition of speaking voice characteristics and phonetograms in untrained and trained vocal groups.

    PubMed

    Awan, S N

    1993-03-01

    This study details a comparison of the speaking F0 and intensity values of young male and female adults with and without vocal training, as well as the superimposition of the speaking F0 and intensity data upon phonetograms. Results indicated that (a) trained vocalists have similar mean speaking F0's than do untrained vocalists, but exhibit significantly greater speaking F0 ranges than do untrained vocalists; (b) trained vocalists are significantly greater mean intensity levels in speech, as well as significantly greater speaking intensity ranges than do untrained vocalists; (c) the mean speaking F0 for both trained and untrained vocalists was found in the vicinity of the 5-7% frequency level of the entire phonational F0 range (in Hz), equivalent to 12-16% of the phonational F0 range in semitones; (d) the overall speech area (mean speaking F0 and minimum and maximum speaking F0 peaks) was found in the lower 23-31% of the entire phonational F0 range (in semitones), with the untrained subjects utilizing the lower 25% of the phonational range (in semitones) and the trained subjects extending this area to the lower 28-31%; and (e) significant correlations were observed between the total intensity range and intensity range used in speech in trained female vocalists and between total F0 range and speaking F0 range in the combined trained male and female group. These results have important implications for the use of the phonetogram, as well as the clinical applicability of vocal training exercises in various speech and voice therapy cases.

  19. Teachers' voice use in teaching environments: a field study using ambulatory phonation monitor.

    PubMed

    Lyberg Åhlander, Viveka; Pelegrín García, David; Whitling, Susanna; Rydell, Roland; Löfqvist, Anders

    2014-11-01

    This case-control designed field study examines the vocal behavior in teachers with self-estimated voice problems (VP) and their age- and school-matched voice healthy (VH) colleagues. It was hypothesized that teachers with and teachers without VP use their voices differently regarding fundamental frequency, sound pressure level (SPL), and in relation to the background noise. Teachers with self-estimated VP (n = 14; two males and 12 females) were age and gender matched to VH school colleagues (n = 14; two males and 12 females). The subjects, recruited from an earlier study, had been examined in laryngeal, vocal, hearing, and psychosocial aspects. The fundamental frequency, SPL, and phonation time were recorded with an Ambulatory Phonation Monitor during one representative workday. The teachers reported their activities in a structured diary. The SPL (including teachers' and students' activity and ambient noise) was recorded with a sound level meter; the room temperature and air quality were measured simultaneously. The acoustic properties of the empty classrooms were measured. Teachers with VP behaved vocally different from their VH peers, in particular during teaching sessions. The phonation time was significantly higher in the group with VP, and the number of vibratory cycles differed between the female teachers. The F0 pattern, related to the vocal SPL and room acoustics, differed between the groups. The results suggest a different vocal behavior in subjects with subjective VP and a higher vocal load with fewer possibilities for vocal recovery. Copyright © 2014 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  20. High-speed registration of phonation-related glottal area variation during artificial lengthening of the vocal tract.

    PubMed

    Laukkanen, Anne-Maria; Pulakka, Hannu; Alku, Paavo; Vilkman, Erkki; Hertegård, Stellan; Lindestad, Per-Ake; Larsson, Hans; Granqvist, Svante

    2007-01-01

    Vocal exercises that increase the vocal tract impedance are widely used in voice training and therapy. The present study applies a versatile methodology to investigate phonation during varying artificial extension of the vocal tract. Two males and one female phonated into a hard-walled plastic tube (phi 2 cm), whose physical length was randomly pair-wise changed between 30 cm, 60 cm and 100 cm. High-speed image (1900 f/sec) sequences of the vocal folds were obtained via a rigid endoscope. Acoustic and electroglottographic signals (EGG) were recorded. Oral pressure during shuttering of the tube was used to give an estimate of subglottic pressure (Psub). The only trend observed was that with the two longer tubes compared to the shortest one, fundamental frequency was lower, open time of the glottis shorter, and Psub higher. The results may partly reflect increased vocal tract impedance as such and partly the increased vocal effort to compensate for it. In other parameters there were individual differences in tube length-related changes, suggesting complexity of the coupling between supraglottic space and the glottis.

  1. Generalised form of a power law threshold function for rainfall-induced landslides

    NASA Astrophysics Data System (ADS)

    Cepeda, Jose; Díaz, Manuel Roberto; Nadim, Farrokh; Høeg, Kaare; Elverhøi, Anders

    2010-05-01

    The following new function is proposed for estimating thresholds for rainfall-triggered landslides: I = α1Anα2Dβ, where I is rainfall intensity in mm/h, D is rainfall duration in h, An is the n-hours or n-days antecedent precipitation, and α1, α2, β and n are threshold parameters. A threshold model that combines two functions with different durations of antecedent precipitation is also introduced. A storm observation exceeds the threshold when the storm parameters are located at or above the two functions simultaneously. A novel optimisation procedure for estimating the threshold parameters is proposed using Receiver Operating Characteristics (ROC) analysis. The new threshold function and optimisation procedure are applied for estimating thresholds for triggering of debris flows in the Western Metropolitan Area of San Salvador (AMSS), El Salvador, where up to 500 casualties were produced by a single event. The resulting thresholds are I = 2322 A7d-1D-0.43 and I = 28534 A150d-1D-0.43 for debris flows having volumes greater than 3000 m3. Thresholds are also derived for debris flows greater than 200 000 m3 and for hyperconcentrated flows initiating in burned areas caused by forest fires. The new thresholds show an improved performance compared to the traditional formulations, indicated by a reduction in false alarms from 51 to 5 for the 3000 m3 thresholds and from 6 to 0 false alarms for the 200 000 m3 thresholds.

  2. Prediction of spatially explicit rainfall intensity-duration thresholds for post-fire debris-flow generation in the western United States

    NASA Astrophysics Data System (ADS)

    Staley, Dennis; Negri, Jacquelyn; Kean, Jason

    2016-04-01

    Population expansion into fire-prone steeplands has resulted in an increase in post-fire debris-flow risk in the western United States. Logistic regression methods for determining debris-flow likelihood and the calculation of empirical rainfall intensity-duration thresholds for debris-flow initiation represent two common approaches for characterizing hazard and reducing risk. Logistic regression models are currently being used to rapidly assess debris-flow hazard in response to design storms of known intensities (e.g. a 10-year recurrence interval rainstorm). Empirical rainfall intensity-duration thresholds comprise a major component of the United States Geological Survey (USGS) and the National Weather Service (NWS) debris-flow early warning system at a regional scale in southern California. However, these two modeling approaches remain independent, with each approach having limitations that do not allow for synergistic local-scale (e.g. drainage-basin scale) characterization of debris-flow hazard during intense rainfall. The current logistic regression equations consider rainfall a unique independent variable, which prevents the direct calculation of the relation between rainfall intensity and debris-flow likelihood. Regional (e.g. mountain range or physiographic province scale) rainfall intensity-duration thresholds fail to provide insight into the basin-scale variability of post-fire debris-flow hazard and require an extensive database of historical debris-flow occurrence and rainfall characteristics. Here, we present a new approach that combines traditional logistic regression and intensity-duration threshold methodologies. This method allows for local characterization of both the likelihood that a debris-flow will occur at a given rainfall intensity, the direct calculation of the rainfall rates that will result in a given likelihood, and the ability to calculate spatially explicit rainfall intensity-duration thresholds for debris-flow generation in recently burned areas. Our approach synthesizes the two methods by incorporating measured rainfall intensity into each model variable (based on measures of topographic steepness, burn severity and surface properties) within the logistic regression equation. This approach provides a more realistic representation of the relation between rainfall intensity and debris-flow likelihood, as likelihood values asymptotically approach zero when rainfall intensity approaches 0 mm/h, and increase with more intense rainfall. Model performance was evaluated by comparing predictions to several existing regional thresholds. The model, based upon training data collected in southern California, USA, has proven to accurately predict rainfall intensity-duration thresholds for other areas in the western United States not included in the original training dataset. In addition, the improved logistic regression model shows promise for emergency planning purposes and real-time, site-specific early warning. With further validation, this model may permit the prediction of spatially-explicit intensity-duration thresholds for debris-flow generation in areas where empirically derived regional thresholds do not exist. This improvement would permit the expansion of the early-warning system into other regions susceptible to post-fire debris flow.

  3. AERODYNAMIC SOUND OF A BODY IN ARBITRARY, DEFORMABLE MOTION, WITH APPLICATION TO PHONATION

    PubMed Central

    Howe, M. S.; McGowan, R. S.

    2012-01-01

    The method of tailored Green’s functions advocated by Doak (Proceedings of the Royal Society A254 (1960) 129 – 145.) for the solution of aeroacoustic problems is used to analyse the contribution of the mucosal wave to self-sustained modulation of air flow through the glottis during the production of voiced speech. The amplitude and phase of the aerodynamic surface force that maintains vocal fold vibration are governed by flow separation from the region of minimum cross-sectional area of the glottis, which moves back and forth along its effective length accompanying the mucosal wave peak. The correct phasing is achieved by asymmetric motion of this peak during the opening and closing phases of the glottis. Limit cycle calculations using experimental data of Berry et al. (Journal of the Acoustical Society of America 110 (2001) 2539 – 2547.) obtained using an excised canine hemilarynx indicate that the mechanism is robust enough to sustain oscillations over a wide range of voicing conditions. PMID:24031098

  4. Effects of a Straw Phonation Protocol on Acoustic and Perceptual Measures of an SATB Chorus.

    PubMed

    Manternach, Jeremy N; Daugherty, James F

    2017-12-29

    Recent scholarship has suggested that semi-occluded vocal tract (SOVT) exercises may increase vocal economy of individuals by reducing vocal effort while maintaining or increasing acoustic output. Choral singers, however, may use different resonance techniques or change voicing behaviors in an effort to hear their own sound in relation to others. One investigation revealed significant increases in a choir's mean spectral energy after participating in a straw phonation protocol. However, that study reported only acoustic measures and did not include choristers' perceptions of the choral sound and their own voicing efficiency. The purpose of this study was to measure the effect of a straw phonation protocol on acoustic (long-term average spectrum) and perceptual (self-report) measures of the choral sound of an intact soprano, alto, tenor, and bass (SATB) choir. This is a quasi-experimental, one-group, pretest-posttest design. An SATB choir (N = 48 singers) performed a Renaissance motet, participated in a 4-minute voicing protocol with a small straw, and then sang the motet a second time. They completed the same procedure later in the rehearsal. Long-term average spectrum results indicated no statistically significant mean changes in spectral energy after the SOVT protocols. Most participants, however, perceived that the choir sounded better (78.26%) and that their own vocal production was more efficient or comfortable (73.91%) following the protocol. Choristers perceived less vocal effort while maintaining vocal output after straw phonation, which may feasibly align with extant solo research. More research may determine whether this result is due specifically to SOVTs. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  5. Materials of acoustic analysis: sustained vowel versus sentence.

    PubMed

    Moon, Kyung Ray; Chung, Sung Min; Park, Hae Sang; Kim, Han Su

    2012-09-01

    Sustained vowel is a widely used material of acoustic analysis. However, vowel phonation does not sufficiently demonstrate sentence-based real-life phonation, and biases may occur depending on the test subjects intent during pronunciation. The purpose of this study was to investigate the differences between the results of acoustic analysis using each material. An individual prospective study. Two hundred two individuals (87 men and 115 women) with normal findings in videostroboscopy were enrolled. Acoustic analysis was done using the speech pattern element acquisition and display program. Fundamental frequency (Fx), amplitude (Ax), contact quotient (Qx), jitter, and shimmer were measured with sustained vowel-based acoustic analysis. Average fundamental frequency (FxM), average amplitude (AxM), average contact quotient (QxM), Fx perturbation (CFx), and amplitude perturbation (CAx) were measured with sentence-based acoustic analysis. Corresponding data of the two methods were compared with each other. SPSS (Statistical Package for the Social Sciences, Version 12.0; SPSS, Inc., Chicago, IL) software was used for statistical analysis. FxM was higher than Fx in men (Fx, 124.45 Hz; FxM, 133.09 Hz; P=0.000). In women, FxM seemed to be lower than Fx, but the results were not statistically significant (Fx, 210.58 Hz; FxM, 208.34 Hz; P=0.065). There was no statistical significance between Ax and AxM in both the groups. QxM was higher than Qx in men and women. Jitter was lower in men, but CFx was lower in women. Both Shimmer and CAx were higher in men. Sustained vowel phonation could not be a complete substitute for real-time phonation in acoustic analysis. Characteristics of acoustic materials should be considered when choosing the material for acoustic analysis and interpreting the results. Copyright © 2012 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  6. Does Cervical Muscular Contraction Affect the Measurement for Electroglottographic Perturbation Parameters?

    PubMed

    Hosokawa, Kiyohito; Ogawa, Makoto; Iwahashi, Toshihiko; Hashimoto, Michiko; Inohara, Hidenori

    2015-11-01

    The purpose was to assess whether cervical muscular contraction during phonation influences the period and amplitude perturbation quotients (PPQ and APQ, respectively) of electroglottographic (EGG) signals, and whether high-pass filtering can attenuate these effects. Prospective. We included 19 nondysphonic speakers and 21 patients with muscle tension dysphonia. During the recording of acoustic and EGG signals, each participant was instructed to naturally phonate sustained vowels /i:/ and /a:/ (NP tasks), and additionally, each nondysphonic participant was asked to phonate the same vowels in a nondysphonic voice quality while contracting the cervical muscles (muscular contracted phonation [MCP] tasks). To confirm the contraction, surface and needle electromyography (EMG) was performed. The EGG signals were high-pass filtered at different cutoff frequencies from 0 to 90 Hz and were subsequently analyzed for the PPQ and APQ. Compared with the NP tasks, the MCP tasks enhanced the cervical EMG activities ranging from 0 to more than 1000 Hz, but conferred only low-frequency noise to the EGG signals under 50 Hz and increased the values for EGG-APQ, but not EGG-PPQ. These EGG-APQ values exhibited gradual decreases after high-pass filtering with an increase in the cutoff frequency ranging from 0 to 50 Hz in both groups, followed by plateaus during the MCP tasks in the nondysphonic group. The present results demonstrate that cervical muscular contraction seriously affects the EGG-APQ values for unfiltered EGG signals independent of the EMG activities and that appropriate high-pass filtering over 50 Hz can attenuate these effects. Copyright © 2015 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  7. Aerobic Exercise as a Warm-up for Singing: Acoustic Impacts.

    PubMed

    McHenry, Monica A; Evans, Joseph

    2017-07-01

    In a previous work, it was found that a 30-minute aerobic workout significantly increased singers' sound pressure level and airflow during voicing, suggesting a shift to flow phonation. This companion study was designed to assess the impact of the same workout on pitch accuracy, vibrato rate, extent and regularity, and the singing power ratio. This study is a cohort experimental study. Twenty-two students in an academic vocal performance program participated. They performed an aerobic workout for 30 minutes. Before and after the workout, they sang the first seven notes of the "Star-Spangled Banner" on /pa/, producing seven /pa/s on the last note. The students then sang an ascending and descending scale to the ninth on "ah." The following measures were obtained from the "Star-Spangled Banner": pitch accuracy calculated on the seventh note ("by"); and vibrato rate, regularity, and extent, calculated on the most sustained sixth note ("see"). For the scale, the following measures were calculated from each note: pitch accuracy; vibrato rate, regularity, and extent; and the singing power ratio. There were no significant differences from pre- to postworkout across any measures. It appears that an aerobic workout positively impacts the respiratory driving force for voice production but does little for phonation. Critical for performance is the fine tuning and balancing across the respiratory, laryngeal, and resonance systems. It appears that this can only be achieved with vocalization exercises, facilitating coordination within and across the physiological systems involved in the complex art of bel canto. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  8. Evaluation of Analytical Modeling Functions for the Phonation Onset Process.

    PubMed

    Petermann, Simon; Kniesburges, Stefan; Ziethe, Anke; Schützenberger, Anne; Döllinger, Michael

    2016-01-01

    The human voice originates from oscillations of the vocal folds in the larynx. The duration of the voice onset (VO), called the voice onset time (VOT), is currently under investigation as a clinical indicator for correct laryngeal functionality. Different analytical approaches for computing the VOT based on endoscopic imaging were compared to determine the most reliable method to quantify automatically the transient vocal fold oscillations during VO. Transnasal endoscopic imaging in combination with a high-speed camera (8000 fps) was applied to visualize the phonation onset process. Two different definitions of VO interval were investigated. Six analytical functions were tested that approximate the envelope of the filtered or unfiltered glottal area waveform (GAW) during phonation onset. A total of 126 recordings from nine healthy males and 210 recordings from 15 healthy females were evaluated. Three criteria were analyzed to determine the most appropriate computation approach: (1) reliability of the fit function for a correct approximation of VO; (2) consistency represented by the standard deviation of VOT; and (3) accuracy of the approximation of VO. The results suggest the computation of VOT by a fourth-order polynomial approximation in the interval between 32.2 and 67.8% of the saturation amplitude of the filtered GAW.

  9. Use of loud phonation as a voice therapy technique for children with vocal nodules

    NASA Astrophysics Data System (ADS)

    Kobayashi, Noriko; Hirose, Hajime; Nishiyama, Koichiro

    2003-10-01

    For the treatment of vocal nodules, educational programs for vocal hygiene and voice training for acquisition of correct phonation are essential. In the case of children, special considerations are necessary as some of their vocal behaviors and reaction to voice disorders are different from those of adults. In this study, a voice therapy program for child vocal nodules were developed and good results were obtained for six children. They were four boys and two girls (Age: 4-11 yr) and bilateral nodules were found for all of them. In addition to a conventional vocal hygiene program for children, correct production of loud voice (so-called gBeltingh) was the major focus of the voice therapy as the visual inspection of the larynges and perceptual evaluations of the voice revealed inappropriate loud voice production with laryngeal constriction in all children. After 5-24 voice therapy sessions, disappearance of the nodules was found in five children and the reduction of the nodule sizes was found in one child. Improvement of the GRBAS scores, longer maximum phonation time, and extension of vocal ranges were found after the completion of the therapy programs.

  10. Analysis of high-speed digital phonoscopy pediatric images

    NASA Astrophysics Data System (ADS)

    Unnikrishnan, Harikrishnan; Donohue, Kevin D.; Patel, Rita R.

    2012-02-01

    The quantitative characterization of vocal fold (VF) motion can greatly enhance the diagnosis and treatment of speech pathologies. The recent availability of high-speed systems has created new opportunities to understand VF dynamics. This paper presents quantitative methods for analyzing VF dynamics with high-speed digital phonoscopy, with a focus on expected VF changes during childhood. A robust method for automatic VF edge tracking during phonation is introduced and evaluated against 4 expert human observers. Results from 100 test frames show a subpixel difference between the VF edges selected by algorithm and expert observers. Waveforms created from the VF edge displacement are used to created motion features with limited sensitivity to variations of camera resolution on the imaging plane. New features are introduced based on acceleration ratios of critical points over each phonation cycle, which have the potential for studying issues related to impact stress. A novel denoising and hybrid interpolation/extrapolation scheme is also introduced to reduce the impact of quantization errors and large sampling intervals relative to the phonation cycle. Features extracted from groups of 4 adults and 5 children show large differences for features related to asymmetry between the right and left fold and consistent differences for impact acceleration ratio.

  11. Detecting Parkinson's disease from sustained phonation and speech signals.

    PubMed

    Vaiciukynas, Evaldas; Verikas, Antanas; Gelzinis, Adas; Bacauskiene, Marija

    2017-01-01

    This study investigates signals from sustained phonation and text-dependent speech modalities for Parkinson's disease screening. Phonation corresponds to the vowel /a/ voicing task and speech to the pronunciation of a short sentence in Lithuanian language. Signals were recorded through two channels simultaneously, namely, acoustic cardioid (AC) and smart phone (SP) microphones. Additional modalities were obtained by splitting speech recording into voiced and unvoiced parts. Information in each modality is summarized by 18 well-known audio feature sets. Random forest (RF) is used as a machine learning algorithm, both for individual feature sets and for decision-level fusion. Detection performance is measured by the out-of-bag equal error rate (EER) and the cost of log-likelihood-ratio. Essentia audio feature set was the best using the AC speech modality and YAAFE audio feature set was the best using the SP unvoiced modality, achieving EER of 20.30% and 25.57%, respectively. Fusion of all feature sets and modalities resulted in EER of 19.27% for the AC and 23.00% for the SP channel. Non-linear projection of a RF-based proximity matrix into the 2D space enriched medical decision support by visualization.

  12. Adductor spasmodic dysphonia: Relationships between acoustic indices and perceptual judgments

    NASA Astrophysics Data System (ADS)

    Cannito, Michael P.; Sapienza, Christine M.; Woodson, Gayle; Murry, Thomas

    2003-04-01

    This study investigated relationships between acoustical indices of spasmodic dysphonia and perceptual scaling judgments of voice attributes made by expert listeners. Audio-recordings of The Rainbow Passage were obtained from thirty one speakers with spasmodic dysphonia before and after a BOTOX injection of the vocal folds. Six temporal acoustic measures were obtained across 15 words excerpted from each reading sample, including both frequency of occurrence and percent time for (1) aperiodic phonation, (2) phonation breaks, and (3) fundamental frequency shifts. Visual analog scaling judgments were also obtained from six voice experts using an interactive computer interface to quantify four voice attributes (i.e., overall quality, roughness, brokenness, breathiness) in a carefully psychoacoustically controlled environment, using the same reading passages as stimuli. Number and percent aperiodicity and phonation breaks correlated significanly with perceived overall voice quality, roughness, and brokenness before and after the BOTOX injection. Breathiness was correlated with aperidocity only prior to injection, while roughness also correlated with frequency shifts following injection. Factor analysis reduced perceived attributes to two principal components: glottal squeezing and breathiness. The acoustic measures demonstrated a strong regression relationship with perceived glottal squeezing, but no regression relationship with breathiness was observed. Implications for an analysis of pathologic voices will be discussed.

  13. Acoustic Propagation Studies For Sperm Whale Phonation Analysis During LADC Experiments

    NASA Astrophysics Data System (ADS)

    Sidorovskaia, Natalia A.; Ioup, George E.; Ioup, Juliette W.; Caruthers, Jerald W.

    2004-11-01

    The Littoral Acoustic Demonstration Center (LADC) conducted a series of passive acoustic experiments in the Northern Gulf of Mexico and the Ligurian Sea in 2001 and 2002. Environmental and acoustic moorings were deployed in areas of large concentrations of marine mammals (mainly, sperm whales). Recordings and analysis of whale phonations are among the objectives of the project. Each mooring had a single autonomously recording hydrophone (Environmental Acoustic Recording System (EARS)) obtained from the U.S. Naval Oceanographic Office after modification to record signals up to 5,859 Hz in the Gulf of Mexico and up to 12,500 Hz in the Ligurian Sea. Self-recording environmental sensors, attached to the moorings, and concurrent environmental ship surveys provided the environmental data for the experiments. The results of acoustic simulations of long-range propagation of the broad-band (500-6,000 Hz) phonation pulses from a hypothetical whale location to the recording hydrophone in the experimental environments are presented. The utilization of the simulation results for an interpretation of the spectral features observed in whale clicks and for the development of tracking algorithms from single hydrophone recordings based on the identification of direct and surface and bottom reflected arrivals are discussed. [Research supported by ONR.

  14. Bedside screen for oral cavity structure, salivary flow, and vocal production over the 14days following endotracheal extubation.

    PubMed

    Chen, Cheryl Chia-Hui; Wu, Kuo-Hsiang; Ku, Shih-Chi; Chan, Ding-Cheng; Lee, Jang-Jaer; Wang, Tyng-Guey; Hsiao, Tzu-Yu

    2018-06-01

    To describe the sequelae of oral endotracheal intubation by evaluating prevalence rates of structural injury, hyposalivation, and impaired vocal production over 14days following extubation. Consecutive adults (≥20years, N=114) with prolonged (≥48h) endotracheal intubation were enrolled from medical intensive care units at a university hospital. Participants were assessed by trained nurses at 2, 7, and 14days after extubation, using a standardized bedside screening protocol. Within 48-hour postextubation, structural injuries were common, with 51% having restricted mouth opening. Unstimulated salivary flow was reduced in 43%. For vocal production, 51% had inadequate breathing support for phonation, dysphonia was common (94% had hoarseness and 36% showed reduced efficiency of vocal fold closure), and >40% had impaired articulatory precision. By 14days postextubation, recovery was noted in most conditions, but reduced efficiency of vocal fold closure persisted. Restricted mouth opening (39%) and reduced salivary flow (34%) remained highly prevalent. After extubation, restricted mouth opening, reduced salivary flow, and dysphonia were common and prolonged in recovery. Reduced efficiency of vocal cord closure persisted at 14days postextubation. The extent and duration of these sequelae remind clinicians to screen for them up to 2weeks after extubation. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. Surface Runoff Threshold Responses to Rainfall Intensity, Scale, and Land Use Type, Change and Disturbance

    NASA Astrophysics Data System (ADS)

    Bhaskar, A.; Kampf, S. K.; Green, T. R.; Wilson, C.; Wagenbrenner, J.; Erksine, R. H.

    2017-12-01

    The dominance of infiltration-excess (Hortonian) overland flow can be determined by how well a rainfall intensity threshold predicts streamflow response. Areas in which we would expect infiltration-excess overland flow to dominate include urban, bedrock, desert pavement, and lands disturbed by vegetation removal (e.g., after a fire burn or fallow agricultural lands). Using a transferable method of identifying the existence of thresholds, we compare the following sites to investigate their hydrologic responses to 60-minute rainfall intensities: desert pavement sites in Arizona (Walnut Gulch and Yuma Proving Ground), post-fire sites in a forested, mountainous burn area in north-central Colorado (High Park Fire), an area of northeastern Colorado Plains that has transitioned from dryland agriculture to conservation reserve (Drake Farm), and watersheds in suburban Baltimore, Maryland which range from less than 5% to over 50% impervious surface cover. We observed that at desert sites, the necessary threshold of rainfall intensity to produce flow increased with watershed size. In burned watersheds, watershed size did not have a clear effect on rainfall thresholds, but thresholds increased with time after burning, with streamflow no longer exhibiting clear threshold responses after the third year post-fire. At the agricultural site, the frequency of runoff events decreased during the transition from cultivated crops to mixed perennial native grasses. In an area where the natural land cover (forested) would be not dominated by infiltration-excess overland flow, urbanization greatly lowered the rainfall thresholds needed for hydrologic response. This work contributes to building a predictive framework for identifying what naturally-occurring landscapes are dominated by infiltration-excess overland flow, and how land use change could shift the dominance of infiltration-excess overland flow. Characterizing the driving mechanism for streamflow generation will allow better prediction of hydrologic response to rainfall events.

  16. Normalizing rainfall/debris-flow thresholds along the U.S. Pacific coast for long-term variations in precipitation climate

    USGS Publications Warehouse

    Wilson, Raymond C.

    1997-01-01

    Broad-scale variations in long-term precipitation climate may influence rainfall/debris-flow threshold values along the U.S. Pacific coast, where both the mean annual precipitation (MAP) and the number of rainfall days (#RDs) are controlled by topography, distance from the coastline, and geographic latitude. Previous authors have proposed that rainfall thresholds are directly proportional to MAP, but this appears to hold only within limited areas (< 1?? latitude), where rainfall frequency (#RDs) is nearly constant. MAP-normalized thresholds underestimate the critical rainfall when applied to areas to the south, where the #RDs decrease, and overestimate threshold rainfall when applied to areas to the north, where the #RDs increase. For normalization between climates where both MAP and #RDs vary significantly, thresholds may best be described as multiples of the rainy-day normal, RDN = MAP/#RDs. Using data from several storms that triggered significant debris-flow activity in southern California, the San Francisco Bay region, and the Pacific Northwest, peak 24-hour rainfalls were plotted against RDN values, displaying a linear relationship with a lower bound at about 14 RDN. RDN ratios in this range may provide a threshold for broad-scale regional forecasting of debris-flow activity.

  17. The effect of vocal fold vertical stiffness gradient on sound production

    NASA Astrophysics Data System (ADS)

    Geng, Biao; Xue, Qian; Zheng, Xudong

    2015-11-01

    It is observed in some experimental studies on canine vocal folds (VFs) that the inferior aspect of the vocal fold (VF) is much stiffer than the superior aspect under relatively large strain. Such vertical difference is supposed to promote the convergent-divergent shape during VF vibration and consequently facilitate the production of sound. In this study, we investigate the effect of vertical variation of VF stiffness on sound production using a numerical model. The vertical variation of stiffness is produced by linearly increasing the Young's modulus and shear modulus from the superior to inferior aspects in the cover layer, and its effect on phonation is examined in terms of aerodynamic and acoustic quantities such as flow rate, open quotient, skewness of flow wave form, sound intensity and vocal efficiency. The flow-induced vibration of the VF is solved with a finite element solver coupled with 1D Bernoulli equation, which is further coupled with a digital waveguide model. This study is designed to find out whether it's beneficial to artificially induce the vertical stiffness gradient by certain implanting material in VF restoring surgery, and if it is beneficial, what gradient is the most favorable.

  18. Rainfall control of debris-flow triggering in the Réal Torrent, Southern French Prealps

    NASA Astrophysics Data System (ADS)

    Bel, Coraline; Liébault, Frédéric; Navratil, Oldrich; Eckert, Nicolas; Bellot, Hervé; Fontaine, Firmin; Laigle, Dominique

    2017-08-01

    This paper investigates the occurrence of debris flow due to rainfall forcing in the Réal Torrent, a very active debris flow-prone catchment in the Southern French Prealps. The study is supported by a 4-year record of flow responses and rainfall events, from three high-frequency monitoring stations equipped with geophones, flow stage sensors, digital cameras, and rain gauges measuring rainfall at 5-min intervals. The classic method of rainfall intensity-duration (ID) threshold was used, and a specific emphasis was placed on the objective identification of rainfall events, as well as on the discrimination of flow responses observed above the ID threshold. The results show that parameters used to identify rainfall events significantly affect the ID threshold and are likely to explain part of the threshold variability reported in the literature. This is especially the case regarding the minimum duration of rain interruption (MDRI) between two distinct rainfall events. In the Réal Torrent, a 3-h MDRI appears to be representative of the local rainfall regime. A systematic increase in the ID threshold with drainage area was also observed from the comparison of the three stations, as well as from the compilation of data from experimental debris-flow catchments. A logistic regression used to separate flow responses above the ID threshold, revealed that the best predictors are the 5-min maximum rainfall intensity, the 48-h antecedent rainfall, the rainfall amount and the number of days elapsed since the end of winter (used as a proxy of sediment supply). This emphasizes the critical role played by short intense rainfall sequences that are only detectable using high time-resolution rainfall records. It also highlights the significant influence of antecedent conditions and the seasonal fluctuations of sediment supply.

  19. Lubrication mechanism of the larynx during phonation: an experiment in excised canine larynges.

    PubMed

    Nakagawa, H; Fukuda, H; Kawaida, M; Shiotani, A; Kanzaki, J

    1998-01-01

    To evaluate how the viscosity of the laryngeal mucus influences vocal fold vibration, two fluids of differing viscosity were applied separately to excised canine larynges and experimental phonation was induced. Vibration of the vocal folds was measured by use of a laryngostroboscope and an X-ray stroboscope. With the high viscosity fluid, the amplitude of vibration of the free edge and the peak glottal area was decreased while the open quotient was increased. Because the viscosity of this fluid affected the wave motion of the vocal fold mucosa, changes in viscosity of the mucus may be involved in causing such disorders as hoarseness, in the absence of apparent changes in the vocal folds themselves.

  20. Critical, sustainable and threshold fluxes for membrane filtration with water industry applications.

    PubMed

    Field, Robert W; Pearce, Graeme K

    2011-05-11

    Critical flux theory evolved as a description of the upper bound in the operating envelope for controlled steady state environments such as cross-flow systems. However, in the application of UF membranes in the water industry, dead-end (direct-flow) designs are used. Direct-flow is a pseudo steady state operation with different fouling characteristics to cross-flow, and thus the critical flux concept has limited applicability. After a review of recent usage of the critical flux theory, an alternative concept for providing design guidelines for direct-flow systems namely that of the threshold flux is introduced. The concept of threshold flux can also be applicable to cross-flow systems. In more general terms the threshold flux can be taken to be the flux that divides a low fouling region from a high fouling region. This may be linked both to the critical flux concept and to the concept of a sustainable flux. The sustainable flux is the one at which a modest degree of fouling occurs, providing a compromise between capital expenditure (which is reduced by using high flux) and operating costs (which are reduced by restricting the fouling rate). Whilst the threshold flux can potentially be linked to physical phenomena alone, the sustainable flux also depends upon economic factors and is thus of a different nature to the critical and threshold fluxes. This distinction will be illustrated using some MBR data. Additionally the utility of the concept of a threshold flux will be illustrated using pilot plant data obtained for UF treatment of four sources of water. Copyright © 2011 Elsevier B.V. All rights reserved.

  1. Turbulent structure in low-concentration drag-reducing channel flows

    NASA Technical Reports Server (NTRS)

    Luchik, T. S.; Tiederman, W. G.

    1988-01-01

    A two-component laser-Doppler velocimeter was used to obtain simultaneous measurements of the velocity components parallel and normal to the wall in two fully developed well-mixed low-concentration drag-reducing channel flows and one turbulent channel flow. For the drag-reducing flows, the average time between bursts was found to increase. Although the basic structure of the fundamental momentum transport event is shown to be the same in these drag-reducing flows, the lower-threshold Reynolds-stress-producing motions were found to be damped, while the higher-threshold motions were not. It is suggested that some strong turbulent motions are needed to maintain extended polymer molecules, which produce a solution with properties that can damp lower threshold turbulence and thereby reduce viscous drag.

  2. Rainfall thresholds for the initiation of debris flows at La Honda, California

    USGS Publications Warehouse

    Wilson, R.C.; Wieczorek, G.F.

    1995-01-01

    A simple numerical model, based on the physical analogy of a leaky barrel, can simulate significant features of the interaction between rainfall and shallow-hillslope pore pressures. The leaky-barrel-model threshold is consistent with, but slightly higher than, an earlier, purely empirical, threshold. The number of debris flows triggered by a storm can be related to the time and amount by which the leaky-barrel-model response exceeded the threshold during the storm. -from Authors

  3. On the thresholds in modeling of high flows via artificial neural networks - A bootstrapping analysis

    NASA Astrophysics Data System (ADS)

    Panagoulia, D.; Trichakis, I.

    2012-04-01

    Considering the growing interest in simulating hydrological phenomena with artificial neural networks (ANNs), it is useful to figure out the potential and limits of these models. In this study, the main objective is to examine how to improve the ability of an ANN model to simulate extreme values of flow utilizing a priori knowledge of threshold values. A three-layer feedforward ANN was trained by using the back propagation algorithm and the logistic function as activation function. By using the thresholds, the flow was partitioned in low (x < μ), medium (μ ≤ x ≤ μ + 2σ) and high (x > μ + 2σ) values. The employed ANN model was trained for high flow partition and all flow data too. The developed methodology was implemented over a mountainous river catchment (the Mesochora catchment in northwestern Greece). The ANN model received as inputs pseudo-precipitation (rain plus melt) and previous observed flow data. After the training was completed the bootstrapping methodology was applied to calculate the ANN confidence intervals (CIs) for a 95% nominal coverage. The calculated CIs included only the uncertainty, which comes from the calibration procedure. The results showed that an ANN model trained specifically for high flows, with a priori knowledge of the thresholds, can simulate these extreme values much better (RMSE is 31.4% less) than an ANN model trained with all data of the available time series and using a posteriori threshold values. On the other hand the width of CIs increases by 54.9% with a simultaneous increase by 64.4% of the actual coverage for the high flows (a priori partition). The narrower CIs of the high flows trained with all data may be attributed to the smoothing effect produced from the use of the full data sets. Overall, the results suggest that an ANN model trained with a priori knowledge of the threshold values has an increased ability in simulating extreme values compared with an ANN model trained with all the data and a posteriori knowledge of the thresholds.

  4. Reductions in finger blood flow induced by 125-Hz vibration: effect of location of contact with vibration.

    PubMed

    Ye, Ying; Griffin, Michael J

    2016-04-01

    This study investigated whether the reductions in finger blood flow induced by 125-Hz vibration applied to different locations on the hand depend on thresholds for perceiving vibration at these locations. Subjects attended three sessions during which vibration was applied to the right index finger, the right thenar eminence, or the left thenar eminence. Absolute thresholds for perceiving vibration at these locations were determined. Finger blood flow in the middle finger of both hands was then measured at 30-s intervals during five successive 5-min periods: (i) pre-exposure, (ii) pre-exposure with 2-N force, (iii) 2-N force with vibration, (iv) post-exposure with 2-N force, (v) recovery. During period (iii), vibration was applied at 15 dB above the absolute threshold for perceiving vibration at the right thenar eminence. Vibration at all three locations reduced finger blood flow on the exposed and unexposed hand, with greater reductions when vibrating the finger. Vibration-induced vasoconstriction was greatest for individuals with low thresholds and locations of excitation with low thresholds. Differences in vasoconstriction between subjects and between locations are consistent with the Pacinian channel mediating both absolute thresholds and vibration-induced vasoconstriction.

  5. The Hagen-Poiseuille, Plane Couette and Poiseuille Flows Linear Instability and Rogue Waves Excitation Mechanism

    NASA Astrophysics Data System (ADS)

    Chefranov, Sergey; Chefranov, Alexander

    2016-04-01

    Linear hydrodynamic stability theory for the Hagen-Poiseuille (HP) flow yields a conclusion of infinitely large threshold Reynolds number, Re, value. This contradiction to the observation data is bypassed using assumption of the HP flow instability having hard type and possible for sufficiently high-amplitude disturbances. HP flow disturbance evolution is considered by nonlinear hydrodynamic stability theory. Similar is the case of the plane Couette (PC) flow. For the plane Poiseuille (PP) flow, linear theory just quantitatively does not agree with experimental data defining the threshold Reynolds number Re= 5772 ( S. A. Orszag, 1971), more than five-fold exceeding however the value observed, Re=1080 (S. J. Davies, C. M. White, 1928). In the present work, we show that the linear stability theory conclusions for the HP and PC on stability for any Reynolds number and evidently too high threshold Reynolds number estimate for the PP flow are related with the traditional use of the disturbance representation assuming the possibility of separation of the longitudinal (along the flow direction) variable from the other spatial variables. We show that if to refuse from this traditional form, conclusions on the linear instability for the HP and PC flows may be obtained for finite Reynolds numbers (for the HP flow, for Re>704, and for the PC flow, for Re>139). Also, we fit the linear stability theory conclusion on the PP flow to the experimental data by getting an estimate of the minimal threshold Reynolds number as Re=1040. We also get agreement of the minimal threshold Reynolds number estimate for PC with the experimental data of S. Bottin, et.al., 1997, where the laminar PC flow stability threshold is Re = 150. Rogue waves excitation mechanism in oppositely directed currents due to the PC flow linear instability is discussed. Results of the new linear hydrodynamic stability theory for the HP, PP, and PC flows are published in the following papers: 1. S.G. Chefranov, A.G. Chefranov, JETP, v.119, No.2, 331, 2014 2. S.G. Chefranov, A.G. Chefranov, Doklady Physics, vol.60, No.7, 327-332, 2015 3. S.G. Chefranov, A. G. Chefranov, arXiv: 1509.08910v1 [physics.flu-dyn] 29 Sep 2015 (accepted to JETP)

  6. Functional outcome of vocal fold medialization thyroplasty with a hydroxyapatite implant.

    PubMed

    Storck, Claudio; Brockmann, Meike; Schnellmann, Elvira; Stoeckli, Sandro J; Schmid, Stephan

    2007-06-01

    Unilateral vocal fold paralysis can cause a persistent incomplete glottal closure during phonation, resulting in impaired voice function. The aim of this study was to evaluate functional results of medialization thyroplasty using a hydroxyapatite implant (VoCoM). Prospective observational cohort study. Between 1999 and 2003, a total of 26 patients (19 men, 7 women) undergoing medialization thyroplasty using a hydroxyapatite implant because of unilateral vocal fold paralysis were enrolled in the study. To evaluate voice function, the following parameters were measured preoperatively and postoperatively: mean fundamental frequency, mean sound pressure level, frequency and amplitude range (voice range profile), and maximum phonation time. A perceptual assessment of hoarseness was conducted using the Roughness, Breathiness, Hoarseness scale. Furthermore, the magnitude of voice related impairment of the patient's communication skills was rated on a 7-point scale. A combined parameter called the Voice Dysfunction Index (VDI) was used to rate vocal performance. All patients showed a statistically significant improvement in the VDI, in perceptual voice analysis, in maximum phonation time, and in the dynamic range of voice. One patient experienced a postoperative wound hemorrhage as a minor complication. No further complications or implant extrusions were observed. Medialization thyroplasty using a hydroxyapatite implant is a secure and efficient phonosurgical procedure. Voice quality and patient satisfaction improve significantly after treatment.

  7. Influence of Asymmetric Recurrent Laryngeal Nerve Stimulation on Vibration, Acoustics, and Aerodynamics

    PubMed Central

    Chhetri, Dinesh K.; Neubauer, Juergen; Sofer, Elazar

    2015-01-01

    Objectives/Hypothesis Evaluate the influence of asymmetric recurrent laryngeal nerve (RLN) stimulation on the vibratory phase, acoustics and aerodynamics of phonation. Study Design Basic science study using an in vivo canine model. Methods The RLNs were symmetrically and asymmetrically stimulated over eight graded levels to test a range of vocal fold activation conditions from subtle paresis to paralysis. Vibratory phase, fundamental frequency (F0), subglottal pressure, and airflow were noted at phonation onset. The evaluations were repeated for three levels of symmetric superior laryngeal nerve (SLN) stimulation. Results Asymmetric laryngeal adductor activation from asymmetric left-right RLN stimulation led to a consistent pattern of vibratory phase asymmetry, with the more activated vocal fold leading in the opening phase of the glottal cycle and in mucosal wave amplitude. Vibratory amplitude asymmetry was also observed, with more lateral excursion of the glottis of the less activated side. Onset fundamental frequency was higher with asymmetric activation because the two RLNs were synergistic in decreasing F0, glottal width, and strain. Phonation onset pressure increased and airflow decreased with symmetric RLN activation. Conclusion Asymmetric laryngeal activation from RLN paresis and paralysis has consistent effects on vocal fold vibration, acoustics, and aerodynamics. This information may be useful in diagnosis and management of vocal fold paresis. PMID:24913182

  8. Influence of asymmetric recurrent laryngeal nerve stimulation on vibration, acoustics, and aerodynamics.

    PubMed

    Chhetri, Dinesh K; Neubauer, Juergen; Sofer, Elazar

    2014-11-01

    Evaluate the influence of asymmetric recurrent laryngeal nerve (RLN) stimulation on the vibratory phase, acoustics and aerodynamics of phonation. Basic science study using an in vivo canine model. The RLNs were symmetrically and asymmetrically stimulated over eight graded levels to test a range of vocal fold activation conditions from subtle paresis to paralysis. Vibratory phase, fundamental frequency (F0 ), subglottal pressure, and airflow were noted at phonation onset. The evaluations were repeated for three levels of symmetric superior laryngeal nerve (SLN) stimulation. Asymmetric laryngeal adductor activation from asymmetric left-right RLN stimulation led to a consistent pattern of vibratory phase asymmetry, with the more activated vocal fold leading in the opening phase of the glottal cycle and in mucosal wave amplitude. Vibratory amplitude asymmetry was also observed, with more lateral excursion of the glottis of the less activated side. Onset fundamental frequency was higher with asymmetric activation because the two RLNs were synergistic in decreasing F0 , glottal width, and strain. Phonation onset pressure increased and airflow decreased with symmetric RLN activation. Asymmetric laryngeal activation from RLN paresis and paralysis has consistent effects on vocal fold vibration, acoustics, and aerodynamics. This information may be useful in diagnosis and management of vocal fold paresis. N/A. © 2014 The American Laryngological, Rhinological and Otological Society, Inc.

  9. Stability of plasma cylinder with current in a helical plasma flow

    NASA Astrophysics Data System (ADS)

    Leonovich, Anatoly S.; Kozlov, Daniil A.; Zong, Qiugang

    2018-04-01

    Stability of a plasma cylinder with a current wrapped by a helical plasma flow is studied. Unstable surface modes of magnetohydrodynamic (MHD) oscillations develop at the boundary of the cylinder enwrapped by the plasma flow. Unstable eigenmodes can also develop for which the plasma cylinder is a waveguide. The growth rate of the surface modes is much higher than that for the eigenmodes. It is shown that the asymmetric MHD modes in the plasma cylinder are stable if the velocity of the plasma flow is below a certain threshold. Such a plasma flow velocity threshold is absent for the symmetric modes. They are unstable in any arbitrarily slow plasma flows. For all surface modes there is an upper threshold for the flow velocity above which they are stable. The helicity index of the flow around the plasma cylinder significantly affects both the Mach number dependence of the surface wave growth rate and the velocity threshold values. The higher the index, the lower the upper threshold of the velocity jump above which the surface waves become stable. Calculations have been carried out for the growth rates of unstable oscillations in an equilibrium plasma cylinder with current serving as a model of the low-latitude boundary layer (LLBL) of the Earth's magnetic tail. A tangential discontinuity model is used to simulate the geomagnetic tail boundary. It is shown that the magnetopause in the geotail LLBL is unstable to a surface wave (having the highest growth rate) in low- and medium-speed solar wind flows, but becomes stable to this wave in high-speed flows. However, it can remain weakly unstable to the radiative modes of MHD oscillations.

  10. Low volume flow meter

    DOEpatents

    Meixler, Lewis D.

    1993-01-01

    The low flow monitor provides a means for determining if a fluid flow meets a minimum threshold level of flow. The low flow monitor operates with a minimum of intrusion by the flow detection device into the flow. The electrical portion of the monitor is externally located with respect to the fluid stream which allows for repairs to the monitor without disrupting the flow. The electronics provide for the adjustment of the threshold level to meet the required conditions. The apparatus can be modified to provide an upper limit to the flow monitor by providing for a parallel electronic circuit which provides for a bracketing of the desired flow rate.

  11. Modulation of Inflammatory and Profibrotic Signaling in a Rabbit Model of Acute Phonotrauma Using Triamcinolone

    PubMed Central

    Hall, Joseph E.; Suehiro, Atsushi; Branski, Ryan C.; Garrett, C. Gaelyn; Rousseau, Bernard

    2015-01-01

    Objective To investigate the hypothesis that prophylactic triamcinolone modulates acute vocal fold inflammatory and profibrotic signaling during acute phonotrauma. Study Design In vivo rabbit phonation model. Setting Academic medical center. Subjects and Methods Forty New Zealand white breeder rabbits were randomly assigned to 1 of 4 groups: control (no intervention), no treatment (30 minutes of raised intensity phonation), sham treatment (bilateral intralaryngeal triamcinolone acetonide injection at 0 μg/25 μL followed by 30 minutes of raised intensity phonation), or steroid treatment (bilateral intralaryngeal triamcinolone acetonide injection at 400 μg/25 μL followed by 30 minutes of raised intensity phonation). Quantitative polymerase chain reaction (qPCR) was used to investigate gene expression levels of cyclooxygenase-2 (COX-2), interleukin (IL)–1β, and transforming growth factor (TGF)–β1. Results Results revealed a significant main effect for COX-2 (P = .002). Post hoc testing revealed that rabbits receiving no treatment (15.10) had higher COX-2 gene expression than control (5.90; P <.001). There were no significant differences in COX-2 expression between treatment groups. Results revealed a significant main effect for IL-1β (P < .001). Post hoc testing revealed that rabbits receiving no treatment (14.70) had higher IL-1β gene expression than control (6.30) (P = .001). There were no significant differences in IL-1β gene expression between treatment groups. There were no significant differences in TGF-β1 gene expression (P = .525) between treatment and control groups. Conclusion Given conflicting evidence, further studies are necessary to investigate vocal fold steroid injections prior to and following the induction of phonotrauma. Prophylactic administration of triamcinolone immediately prior to acute phonotrauma resulted in no significant changes in COX-2, IL-1β, and TGF-β1 gene transcript levels. PMID:22399283

  12. [Immediate recurrent laryngeal nerve reconstruction in the treatment of thyroid cancer invading the recurrent laryngeal nerve].

    PubMed

    Feng, Yun; Yang, Dazhang; Liu, Dandan; Chen, Jian; Bi, Qingling; Luo, Keqiang

    2014-08-01

    To explore the application of immediate recurrent laryngeal nerve reconstruction in the treatment of thyroid cancer invading the recurrent laryngeal nerve. Ten patients with thyroid cancer invading unilateral recurrent laryngeal nerve underwent radical surgery and immediate recurrent laryngeal nerve reconstruction. The reconstructive surgical approach included recurrent laryngeal nerve decompression surgery, end-to-end anastomosis of the recurrent laryngeal nerve, anastomosis of ansa cervicalis nerve to the recurrent laryngeal nerve, and nerve-muscle pedicle (NMP) technique. Among the ten patients, one underwent nerve decompression, one underwent end-to-end anastomosis of the recurrent laryngeal nerve, seven had anastomosis of ansa cervicalis to recurrent laryngeal nerve, and one case had anastomosis of ansa cervicalis to recurrent laryngeal nerve combined with nerve-muscle pedicle (NMP) technique. The effect of surgery was evaluated by videolaryngoscopy, maximum phonation time (MPT), phonation efficiency index (PEI) and voice assessment. T-test was used in the statistical analysis. All of the 10 patients had no complications including tumor recurrence and hypoparathyroidism after the surgery. Their hoarseness symptoms were improved, and the patients returned to normal or near-normal voice. Postoperative videolaryngoscopy showed that paralyzed vocal cord returned to normal muscle tone and volume, and the vocal cord vibration and mucosal wave were symmetric and the patients got good glottal closure. The pre- and post-operative maximum phone times of the patients were (4.52 ± 0.89) s and (11.91 ± 1.87) s, respectively (P < 0.01). The pre- and post-operative phonation efficiency indices were (1.37 ± 0.43) s/L and (4.02 ± 1.33) s/L, respectively (P < 0.05). In patients with thyroid cancer invading unilateral recurrent laryngeal nerve, immediate recurrent laryngeal nerve reconstruction following radical surgery of thyroid cancer can effectively achieve recovery in phonation function and improve the quality of life of the patients.

  13. Systematic Studies of Modified Vocalization: Speech Production Changes During a Variation of Metronomic Speech in Persons Who Do and Do Not Stutter

    PubMed Central

    Davidow, Jason H.; Bothe, Anne K.; Ye, Jun

    2011-01-01

    The most common way to induce fluency using rhythm requires persons who stutter to speak one syllable or one word to each beat of a metronome, but stuttering can also be eliminated when the stimulus is of a particular duration (e.g., 1 s). The present study examined stuttering frequency, speech production changes, and speech naturalness during rhythmic speech that alternated 1 s of reading with 1 s of silence. A repeated-measures design was used to compare data obtained during a control reading condition and during rhythmic reading in 10 persons who stutter (PWS) and 10 normally fluent controls. Ratings for speech naturalness were also gathered from naïve listeners. Results showed that mean vowel duration increased significantly, and the percentage of short phonated intervals decreased significantly, for both groups from the control to the experimental condition. Mean phonated interval length increased significantly for the fluent controls. Mean speech naturalness ratings during the experimental condition were approximately 7 on a 1–9 scale (1 = highly natural; 9 = highly unnatural), and these ratings were significantly correlated with vowel duration and phonated intervals for PWS. The findings indicate that PWS may be altering vocal fold vibration duration to obtain fluency during this rhythmic speech style, and that vocal fold vibration duration may have an impact on speech naturalness during rhythmic speech. Future investigations should examine speech production changes and speech naturalness during variations of this rhythmic condition. Educational Objectives The reader will be able to: (1) describe changes (from a control reading condition) in speech production variables when alternating between 1 s of reading and 1 s of silence, (2) describe which rhythmic conditions have been found to sound and feel the most natural, (3) describe methodological issues for studies about alterations in speech production variables during fluency-inducing conditions, and (4) describe which fluency-inducing conditions have been shown to involve a reduction in short phonated intervals. PMID:21664528

  14. Detection of dilute sperm samples using photoacoustic flowmetry

    NASA Astrophysics Data System (ADS)

    Viator, J. A.; Sutovsky, P.; Weight, R. M.

    2008-02-01

    Detection of sperm cells in dilute samples may have application in forensic testing and diagnosis of male reproductive health. Due to the optically dense subcellular structures in sperm cells, irradiation by nanosecond laser pulses induces a photoacoustic response detectable using a custom flow cytometer. We determined the detection threshold of bull sperm using various concentrations, from 200 to 1,000,000 sperm cells per milliliter. Using a tunable laser system set to 450nm with a 5 ns pulse duration and 11-12 mJ/pulse, we obtained a detection threshold of 3 sperm cells. The flow rate was 4 ml/minute through the flow chamber. The acoustic sensor was a 100 μm PVDF film attached to the glass flow chamber. The acoustic signal was preamplified and sent to an oscilloscope. The threshold signal indicated a signal to noise ratio of approximately 6 to 1. Improved system design may decrease the threshold to single sperm cells.

  15. Aerodynamic sound of a body in arbitrary, deformable motion, with application to phonation

    NASA Astrophysics Data System (ADS)

    Howe, M. S.; McGowan, R. S.

    2013-08-01

    The method of tailored Green's functions advocated by Doak [Acoustic radiation from a turbulent fluid containing foreign bodies, Proceedings of the Royal Society A 254 (1960) 129-145] for the solution of aeroacoustic problems is used to analyse the contribution of the mucosal wave to self-sustained modulation of air flow through the glottis during the production of voiced speech. The amplitude and phase of the aerodynamic surface force that maintains vocal fold vibration are governed by flow separation from the region of minimum cross-sectional area of the glottis, which moves back and forth along its effective length accompanying the mucosal wave peak. The correct phasing is achieved by asymmetric motion of this peak during the opening and closing phases of the glottis. Limit cycle calculations using experimental data of Berry et al. [High-speed digital imaging of the medial surface of the vocal folds, Journal of the Acoustical Society of America110 (2001) 2539-2547] obtained using an excised canine hemilarynx indicate that the mechanism is robust enough to sustain oscillations over a wide range of voicing conditions.

  16. Entrance loss coefficients and exit coefficients for a physical model of the glottis with convergent angles

    PubMed Central

    Fulcher, Lewis P.; Scherer, Ronald C.; Anderson, Nicholas V.

    2014-01-01

    Pressure distributions were obtained for 5°, 10°, and 20° convergent angles with a static physical model (M5) of the glottis. Measurements were made for minimal glottal diameters from d = 0.005–0.32 cm with a range of transglottal pressures of interest for phonation. Entrance loss coefficients were calculated at the glottal entrance for each minimal diameter and transglottal pressure to measure how far the flows in this region deviate from Bernoulli flow. Exit coefficients were also calculated to determine the presence and magnitude of pressure recovery near the glottal exit. The entrance loss coefficients for the three convergent angles vary from values near 2.3–3.4 for d = 0.005 cm to values near 0.6 for d = 0.32 cm. These coefficients extend the tables of entrance loss and exit coefficients obtained for the uniform glottis according to Fulcher, Scherer, and Powell [J. Acoust. Soc. Am. 129, 1548–1553 (2011)]. PMID:25190404

  17. Effect of pneumotach on measurement of vocal function

    NASA Astrophysics Data System (ADS)

    Walters, Gage; McPhail, Michael; Krane, Michael

    2017-11-01

    Aerodynamic and acoustic measurements of vocal function were performed in a physical model of the human airway with and without a pneumotach (Rothenberg mask), used by clinicians to measure vocal volume flow. The purpose of these experiments was to assess whether the device alters acoustic and aerodynamic conditions sufficiently to change phonation behavior. The airway model, which mimics acoustic behavior of an adult human airway from trachea to mouth, consists of a 31.5cm long straight duct with a 2.54cm square cross section. Model vocal folds comprised of molded silicone rubber were set into vibration by introducing airflow from a compressed air source. Measurements included transglottal pressure difference, mean volume flow, vocal fold vibratory motion, and sound pressure measured at the mouth. The experiments show that while the pneumotach imparted measurable aerodynamic and acoustic loads on the system, measurement of mean glottal resistance was not affected. Acoustic pressure levels were attenuated, however, suggesting clinical acoustic measurements of vocal function need correction when performed in conjunction with a pneumotach Acknowledge support from NIH DC R01005642-11.

  18. Photocoagulation of microvascular and hemorrhagic lesions of the vocal fold with the KTP laser.

    PubMed

    Hirano, Shigeru; Yamashita, Masaru; Kitamura, Morimasa; Takagita, Shin-ichi

    2006-04-01

    Ectasias and varices of the vocal fold are microvascular lesions that are often due to chronic abuse of the voice, and are occasionally encountered in association with other disorders such as polyps, Reinke's edema, and hematoma. The KTP laser can be used for photocoagulation of small vascular lesions, because the laser beam is well absorbed by hemoglobin, and damage to the epithelium is minimal. The present pilot study examined how the KTP laser could be used for microvascular lesions and their associated lesions. Twelve patients who had undergone phonomicrosurgery were enrolled in the present study. The microvascular lesions were treated by photocoagulation with the laser set at a low power of 1.5 W in the continuous mode, while preserving the epithelium, and associated lesions were then treated by microdissection with cold instruments. The postoperative phonatory function was assessed by maximum phonation time, a perceptual test rating (GRBAS scale), and stroboscopy. The procedures were completed successfully in all cases. An exceptional case of a small hemorrhagic polyp allowed treatment with the laser only. The postoperative stroboscopic findings, maximum phonation time, and perceptual test rating all showed significant improvement compared with the preoperative state. No adverse effects, such as scarring or reduction of the mucosal wave, were observed in the current series. KTP laser photocoagulation is a relatively simple and safe procedure for treating microvascular lesions of the vocal fold. It is not recommended for photocoagulation of hemorrhagic polyps or hematomas, because such lesions have little blood flow inside and thus photocoagulation is usually impossible or requires too much laser energy. However, photocoagulation of perimeter or feeding vessels of such disorders may facilitate the following procedure by avoiding unnecessary bleeding, as well as preventing recurrence of hemorrhagic lesions.

  19. Experiments on Analysing Voice Production: Excised (Human, Animal) and In Vivo (Animal) Approaches

    PubMed Central

    Döllinger, Michael; Kobler, James; Berry, David A.; Mehta, Daryush D.; Luegmair, Georg; Bohr, Christopher

    2015-01-01

    Experiments on human and on animal excised specimens as well as in vivo animal preparations are so far the most realistic approaches to simulate the in vivo process of human phonation. These experiments do not have the disadvantage of limited space within the neck and enable studies of the actual organ necessary for phonation, i.e., the larynx. The studies additionally allow the analysis of flow, vocal fold dynamics, and resulting acoustics in relation to well-defined laryngeal alterations. Purpose of Review This paper provides an overview of the applications and usefulness of excised (human/animal) specimen and in vivo animal experiments in voice research. These experiments have enabled visualization and analysis of dehydration effects, vocal fold scarring, bifurcation and chaotic vibrations, three-dimensional vibrations, aerodynamic effects, and mucosal wave propagation along the medial surface. Quantitative data will be shown to give an overview of measured laryngeal parameter values. As yet, a full understanding of all existing interactions in voice production has not been achieved, and thus, where possible, we try to indicate areas needing further study. Recent Findings A further motivation behind this review is to highlight recent findings and technologies related to the study of vocal fold dynamics and its applications. For example, studies of interactions between vocal tract airflow and generation of acoustics have recently shown that airflow superior to the glottis is governed by not only vocal fold dynamics but also by subglottal and supraglottal structures. In addition, promising new methods to investigate kinematics and dynamics have been reported recently, including dynamic optical coherence tomography, X-ray stroboscopy and three-dimensional reconstruction with laser projection systems. Finally, we touch on the relevance of vocal fold dynamics to clinical laryngology and to clinically-oriented research. PMID:26581597

  20. Optic flow detection is not influenced by visual-vestibular congruency.

    PubMed

    Holten, Vivian; MacNeilage, Paul R

    2018-01-01

    Optic flow patterns generated by self-motion relative to the stationary environment result in congruent visual-vestibular self-motion signals. Incongruent signals can arise due to object motion, vestibular dysfunction, or artificial stimulation, which are less common. Hence, we are predominantly exposed to congruent rather than incongruent visual-vestibular stimulation. If the brain takes advantage of this probabilistic association, we expect observers to be more sensitive to visual optic flow that is congruent with ongoing vestibular stimulation. We tested this expectation by measuring the motion coherence threshold, which is the percentage of signal versus noise dots, necessary to detect an optic flow pattern. Observers seated on a hexapod motion platform in front of a screen experienced two sequential intervals. One interval contained optic flow with a given motion coherence and the other contained noise dots only. Observers had to indicate which interval contained the optic flow pattern. The motion coherence threshold was measured for detection of laminar and radial optic flow during leftward/rightward and fore/aft linear self-motion, respectively. We observed no dependence of coherence thresholds on vestibular congruency for either radial or laminar optic flow. Prior studies using similar methods reported both decreases and increases in coherence thresholds in response to congruent vestibular stimulation; our results do not confirm either of these prior reports. While methodological differences may explain the diversity of results, another possibility is that motion coherence thresholds are mediated by neural populations that are either not modulated by vestibular stimulation or that are modulated in a manner that does not depend on congruency.

  1. Investigating the effect of freeway congestion thresholds on decision-making inputs.

    DOT National Transportation Integrated Search

    2010-05-01

    Congestion threshold is embedded in the congestion definition. Two basic approaches exist in : current practice for setting the congestion threshold. One common approach uses the free-flow or : unimpeded conditions as the congestion threshold. ...

  2. Influence of vortical flow structures on the glottal jet location in the supraglottal region.

    PubMed

    Kniesburges, Stefan; Hesselmann, Christina; Becker, Stefan; Schlücker, Eberhard; Döllinger, Michael

    2013-09-01

    Within the fully coupled multiphysics phonation process, the fluid flow plays an important role for sound production. This study addresses phenomena in the flow downstream of synthetic self-oscillating vocal folds. An experimental setup consisting of devices for producing and conditioning the flow including the main test channel was applied. The supraglottal channel was designed to prevent an acoustic coupling to the vocal folds. Hence, the oscillations were aerodynamically driven. The cross-section of the supraglottal channel was systematically varied by increasing the distance between the lateral channel walls. The vocal folds consisted of silicone rubber of homogenous material distribution generating self-sustained oscillations. The airflow was visualized in the immediate supraglottal region using a laser-sheet technique and a digital high-speed camera. Furthermore, the flow was studied by measuring the static pressure distributions on both lateral supraglottal channel walls. The results clearly showed different flow characteristics depending on the supraglottal configuration. In all cases with supraglottal channel, the jet was located asymmetrical and bent in medial-lateral direction. Furthermore, the side to which the jet was deflected changed in between the consecutive cycles showing a bifurcational behavior. Previously, this phenomenon was explained by the Coanda effect. However, the present data suggest that the deflection of the jet was mainly caused by large air vortices in the supraglottal channel produced by the flow field of previous oscillations. In contrast, for the case without supraglottal channel, the air jet was found totally symmetrical stabilized by the constant pressure in the ambient region. The emitted sound signal showed additional subharmonic tonal peaks for the asymmetric flow cases, which are characteristics for diplophonia. Copyright © 2013 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  3. THRESH—Software for tracking rainfall thresholds for landslide and debris-flow occurrence, user manual

    USGS Publications Warehouse

    Baum, Rex L.; Fischer, Sarah J.; Vigil, Jacob C.

    2018-02-28

    Precipitation thresholds are used in many areas to provide early warning of precipitation-induced landslides and debris flows, and the software distribution THRESH is designed for automated tracking of precipitation, including precipitation forecasts, relative to thresholds for landslide occurrence. This software is also useful for analyzing multiyear precipitation records to compare timing of threshold exceedance with dates and times of historical landslides. This distribution includes the main program THRESH for comparing precipitation to several kinds of thresholds, two utility programs, and a small collection of Python and shell scripts to aid the automated collection and formatting of input data and the graphing and further analysis of output results. The software programs can be deployed on computing platforms that support Fortran 95, Python 2, and certain Unix commands. The software handles rainfall intensity-duration thresholds, cumulative recent-antecedent precipitation thresholds, and peak intensity thresholds as well as various measures of antecedent precipitation. Users should have predefined rainfall thresholds before running THRESH.

  4. The influence of pitch and loudness changes on the acoustics of vocal tremor.

    PubMed

    Dromey, Christopher; Warrick, Paul; Irish, Jonathan

    2002-10-01

    The effect of tremor on phonation is to modulate an otherwise steady sound source in its amplitude, fundamental frequency, or both. The severity of untreated vocal tremor has been reported to change under certain conditions that may be related to muscle tension. In order to better understand the phenomenon of vocal tremor, its acoustic properties were examined as individuals volitionally altered their pitch and loudness. These voice conditions were anticipated to alter the tension of the intrinsic laryngeal muscles. The voices of 10 individuals with a diagnosis of vocal tremor were recorded before participating in a longitudinal treatment study. They produced vowels at low and high pitch and loudness levels as well as in a comfortable voice condition. Acoustic analyses quantified the amplitude and frequency modulations of the speakers' voices across the various conditions. Individual speakers varied in the way the pitch and loudness changes affected their tremor, but the following statistically significant effects for the speakers as a group were observed: Higher pitch phonation was associated with a more rapid rate for both amplitude and frequency modulations. Amplitude modulation become faster for louder phonation. Low-pitched phonotion led to decreases in the extent of amplitude tremor. Varying pitch led to dramatic changes in the phase relationship between amplitude and frequency modulation in some of the speakers, whereas this effect was not apparent in other speakers.

  5. Effect of Performance Time of the Semi-Occluded Vocal Tract Exercises in Dysphonic Children.

    PubMed

    Ramos, Lorena de Almeida; Gama, Ana Cristina Côrtes

    2017-05-01

    This study aimed to verify the effects of execution time on auditory-perceptual and acoustic responses in children with dysphonia completing straw phonation exercises. A randomized, prospective, comparative intra-subject study design was used. Twenty-seven children, ranging from 5 to 10 years of age, diagnosed with vocal cord nodules or cysts, were enrolled in the study. All subjects included in the Experimental Group were also included in the Control Group which involved complete voice rest. Sustained vowels (/a/e/ε/e/) counting from 1 to 10 were recorded before the exercises (m0) and then again after the first (m1), third (m3), fifth (m5), and seventh (m7) minutes of straw phonation exercises. The recordings were randomized and presented to five speech therapists, who evaluated vocal quality based on the Grade Roughness Breathiness Asthenia/Strain Instability scale. For acoustic analysis, fundamental frequency, jitter, shimmer, glottal to noise excitation ratio, and noise parameters were analyzed. Reduced roughness, breathiness, and noise measurements as well as increased glottal to noise excitation ratio were observed in the Experimental Group after 3 minutes of exercise. Reduced grade of dysphonia and breathiness were noted after 5 minutes. The ideal duration of straw phonation in children with dysphonia is from 3 to 5 minutes. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  6. Phonatory vocal tract stability in stuttering children before and after fluency--enhancing therapy.

    PubMed

    Dehqan, A; Ali Dashti, G; Mirzadeh, M

    2010-01-01

    Stuttering is a complex disorder. Essentially, it is a neuromuscular disorder whose core consists of tiny lags and disruptions in the timing of the complicated movements required for speech. The purpose of the current study was to collec and comparg jitters and shimmer values in children who stutter before and after fluency--enhancing therapy. Subjects consisted of 15 Iranian preschool girls with stutterg, and 15 Iranial preschool girls without afflictions, matched according to age. Vocal jittering and shimmer measurements of thesphonation of the children were compared before and after therapy. Each subject phonated vowels nine times in a random order. Each phonation was sustained for at least five seconds and was recorded. The middle three-second portion of each recorded vowel phonation was subjected to jitter and shimmer analysis. On shimmer measures between pre-treatment and post treatment, significant differences were found in all sustained vowels of persons who stutter group and means of shimmer in post therapy were significantly lower than pre-treatment. Differences in jitter measurements were not significant between pre-treatment and post-treatment statuses and this parameter did not change after therapy. The findings showed that therapy resulted in decreaseg irregularity in the amplitude of vibrations (shimmer). In other words, the therapy increases the steady-state of the laryngeal system. Moreover, this parameter may be used as an index for the effectiveness of therapy.

  7. Towards a debris-flow warning system based on hydrological measurements of the triggering conditions. A study of El Rebaixader catchment (Central Pyrenees, Spain)

    NASA Astrophysics Data System (ADS)

    Abancó, Clàudia; Hürlimann, Marcel; Moya, José

    2014-05-01

    Debris flows represent a risk to the society due to their high destructive power. Rainfall is the main debris-flow triggering factor. Rainfall thresholds are generally used for warning of debris flow occurrence in susceptible catchments. However, the efficiency of such thresholds for real time hazard assessment is often conditioned by many factors, such as: the location and number of the rain gauges used (both to define the thresholds, and for setting off warnings); the temporal and spatial evolution of rainfall's convective cells or the effect of snow cover melting. These factors affect the length of the warning time, which is of crucial importance for issuing alert messages or alarms to the people and infrastructures at risk. The Rebaixader catchment (Central Pyrenees, Spain) is being monitored since 2009 by six stations recording information on initiation (4 stations) and flow detection and cinematic behaviour (2 stations). Until December 2013, 7 debris flows, 17 debris floods and 4 rockfalls have been recorded. The objectives of this work were: a) the definition of rainfall thresholds at two different rain gauges; b) the analysis of the infiltration patterns in order to define their potential use for warning systems and c) preliminary testing of rainfall thresholds' efficiency in terms of warning time, in this catchment. This last goal consisted in the comparison of the time elapsed between the rainfall threshold was exceeded and the event occurrence was detected by the stations at the channel area. The results suggest that the intensity-duration rainfall thresholds sometimes provide warning times which would be too short for an adequate reaction in the Rebaixader catchment (less than 10 minutes). The combination of such rainfall thresholds with infiltration measurements is useful to increase the warning time. This occurs especially in the events triggered in spring, when the snowmelt plays an important role in the event's triggering conditions. However, the effects of infiltration associated to the summer convective rainfalls are almost imperceptible; therefore their importance in warning systems decreases.

  8. Study of dynamic fluid-structure coupling with application to human phonation

    NASA Astrophysics Data System (ADS)

    Saurabh, Shakti; Faber, Justin; Bodony, Daniel

    2013-11-01

    Two-dimensional direct numerical simulations of a compressible, viscous fluid interacting with a non-linear, viscoelastic solid are used to study the generation of the human voice. The vocal fold (VF) tissues are modeled using a finite-strain fractional derivative constitutive model implemented in a quadratic finite element code and coupled to a high-order compressible Navier-Stokes solver through a boundary-fitted fluid-solid interface. The viscoelastic solver is validated through in-house experiments using Agarose Gel, a human tissue simulant, undergoing static and harmonic deformation measured with load cell and optical diagnostics. The phonation simulations highlight the role tissue nonlinearity and viscosity play in the glottal jet dynamics and in the radiated sound. Supported by the National Science Foundation (CAREER award number 1150439).

  9. Gradient-driven flux-tube simulations of ion temperature gradient turbulence close to the non-linear threshold

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Peeters, A. G.; Rath, F.; Buchholz, R.

    2016-08-15

    It is shown that Ion Temperature Gradient turbulence close to the threshold exhibits a long time behaviour, with smaller heat fluxes at later times. This reduction is connected with the slow growth of long wave length zonal flows, and consequently, the numerical dissipation on these flows must be sufficiently small. Close to the nonlinear threshold for turbulence generation, a relatively small dissipation can maintain a turbulent state with a sizeable heat flux, through the damping of the zonal flow. Lowering the dissipation causes the turbulence, for temperature gradients close to the threshold, to be subdued. The heat flux then doesmore » not go smoothly to zero when the threshold is approached from above. Rather, a finite minimum heat flux is obtained below which no fully developed turbulent state exists. The threshold value of the temperature gradient length at which this finite heat flux is obtained is up to 30% larger compared with the threshold value obtained by extrapolating the heat flux to zero, and the cyclone base case is found to be nonlinearly stable. Transport is subdued when a fully developed staircase structure in the E × B shearing rate forms. Just above the threshold, an incomplete staircase develops, and transport is mediated by avalanche structures which propagate through the marginally stable regions.« less

  10. Deriving flow directions for coarse-resolution (1-4 km) gridded hydrologic modeling

    NASA Astrophysics Data System (ADS)

    Reed, Seann M.

    2003-09-01

    The National Weather Service Hydrology Laboratory (NWS-HL) is currently testing a grid-based distributed hydrologic model at a resolution (4 km) commensurate with operational, radar-based precipitation products. To implement distributed routing algorithms in this framework, a flow direction must be assigned to each model cell. A new algorithm, referred to as cell outlet tracing with an area threshold (COTAT) has been developed to automatically, accurately, and efficiently assign flow directions to any coarse-resolution grid cells using information from any higher-resolution digital elevation model. Although similar to previously published algorithms, this approach offers some advantages. Use of an area threshold allows more control over the tendency for producing diagonal flow directions. Analyses of results at different output resolutions ranging from 300 m to 4000 m indicate that it is possible to choose an area threshold that will produce minimal differences in average network flow lengths across this range of scales. Flow direction grids at a 4 km resolution have been produced for the conterminous United States.

  11. FE Modelling of the Fluid-Structure-Acoustic Interaction for the Vocal Folds Self-Oscillation

    NASA Astrophysics Data System (ADS)

    Švancara, Pavel; Horáček, J.; Hrůza, V.

    The flow induced self-oscillation of the human vocal folds in interaction with acoustic processes in the simplified vocal tract model was explored by three-dimensional (3D) finite element (FE) model. Developed FE model includes vocal folds pretension before phonation, large deformations of the vocal fold tissue, vocal folds contact, fluid-structure interaction, morphing the fluid mesh according the vocal folds motion (Arbitrary Lagrangian-Eulerian approach), unsteady viscous compressible airflow described by the Navier-Stokes equations and airflow separation during the glottis closure. Iterative partitioned approach is used for modelling the fluid-structure interaction. Computed results prove that the developed model can be used for simulation of the vocal folds self-oscillation and resulting acoustic waves. The developed model enables to numerically simulate an influence of some pathological changes in the vocal fold tissue on the voice production.

  12. 3D SAPIV particle field reconstruction method based on adaptive threshold.

    PubMed

    Qu, Xiangju; Song, Yang; Jin, Ying; Li, Zhenhua; Wang, Xuezhen; Guo, ZhenYan; Ji, Yunjing; He, Anzhi

    2018-03-01

    Particle image velocimetry (PIV) is a necessary flow field diagnostic technique that provides instantaneous velocimetry information non-intrusively. Three-dimensional (3D) PIV methods can supply the full understanding of a 3D structure, the complete stress tensor, and the vorticity vector in the complex flows. In synthetic aperture particle image velocimetry (SAPIV), the flow field can be measured with large particle intensities from the same direction by different cameras. During SAPIV particle reconstruction, particles are commonly reconstructed by manually setting a threshold to filter out unfocused particles in the refocused images. In this paper, the particle intensity distribution in refocused images is analyzed, and a SAPIV particle field reconstruction method based on an adaptive threshold is presented. By using the adaptive threshold to filter the 3D measurement volume integrally, the three-dimensional location information of the focused particles can be reconstructed. The cross correlations between images captured from cameras and images projected by the reconstructed particle field are calculated for different threshold values. The optimal threshold is determined by cubic curve fitting and is defined as the threshold value that causes the correlation coefficient to reach its maximum. The numerical simulation of a 16-camera array and a particle field at two adjacent time events quantitatively evaluates the performance of the proposed method. An experimental system consisting of a camera array of 16 cameras was used to reconstruct the four adjacent frames in a vortex flow field. The results show that the proposed reconstruction method can effectively reconstruct the 3D particle fields.

  13. Systematic studies of modified vocalization: speech production changes during a variation of metronomic speech in persons who do and do not stutter.

    PubMed

    Davidow, Jason H; Bothe, Anne K; Ye, Jun

    2011-06-01

    The most common way to induce fluency using rhythm requires persons who stutter to speak one syllable or one word to each beat of a metronome, but stuttering can also be eliminated when the stimulus is of a particular duration (e.g., 1 second [s]). The present study examined stuttering frequency, speech production changes, and speech naturalness during rhythmic speech that alternated 1s of reading with 1s of silence. A repeated-measures design was used to compare data obtained during a control reading condition and during rhythmic reading in 10 persons who stutter (PWS) and 10 normally fluent controls. Ratings for speech naturalness were also gathered from naïve listeners. Results showed that mean vowel duration increased significantly, and the percentage of short phonated intervals decreased significantly, for both groups from the control to the experimental condition. Mean phonated interval length increased significantly for the fluent controls. Mean speech naturalness ratings during the experimental condition were approximately "7" on a 1-9 scale (1=highly natural; 9=highly unnatural), and these ratings were significantly correlated with vowel duration and phonated intervals for PWS. The findings indicate that PWS may be altering vocal fold vibration duration to obtain fluency during this rhythmic speech style, and that vocal fold vibration duration may have an impact on speech naturalness during rhythmic speech. Future investigations should examine speech production changes and speech naturalness during variations of this rhythmic condition. The reader will be able to: (1) describe changes (from a control reading condition) in speech production variables when alternating between 1s of reading and 1s of silence, (2) describe which rhythmic conditions have been found to sound and feel the most natural, (3) describe methodological issues for studies about alterations in speech production variables during fluency-inducing conditions, and (4) describe which fluency-inducing conditions have been shown to involve a reduction in short phonated intervals. Copyright © 2011 Elsevier Inc. All rights reserved.

  14. The threshold algorithm: Description of the methodology and new developments

    NASA Astrophysics Data System (ADS)

    Neelamraju, Sridhar; Oligschleger, Christina; Schön, J. Christian

    2017-10-01

    Understanding the dynamics of complex systems requires the investigation of their energy landscape. In particular, the flow of probability on such landscapes is a central feature in visualizing the time evolution of complex systems. To obtain such flows, and the concomitant stable states of the systems and the generalized barriers among them, the threshold algorithm has been developed. Here, we describe the methodology of this approach starting from the fundamental concepts in complex energy landscapes and present recent new developments, the threshold-minimization algorithm and the molecular dynamics threshold algorithm. For applications of these new algorithms, we draw on landscape studies of three disaccharide molecules: lactose, maltose, and sucrose.

  15. Computational Models of Laryngeal Aerodynamics: Potentials and Numerical Costs.

    PubMed

    Sadeghi, Hossein; Kniesburges, Stefan; Kaltenbacher, Manfred; Schützenberger, Anne; Döllinger, Michael

    2018-02-07

    Human phonation is based on the interaction between tracheal airflow and laryngeal dynamics. This fluid-structure interaction is based on the energy exchange between airflow and vocal folds. Major challenges in analyzing the phonatory process in-vivo are the small dimensions and the poor accessibility of the region of interest. For improved analysis of the phonatory process, numerical simulations of the airflow and the vocal fold dynamics have been suggested. Even though most of the models reproduced the phonatory process fairly well, development of comprehensive larynx models is still a subject of research. In the context of clinical application, physiological accuracy and computational model efficiency are of great interest. In this study, a simple numerical larynx model is introduced that incorporates the laryngeal fluid flow. It is based on a synthetic experimental model with silicone vocal folds. The degree of realism was successively increased in separate computational models and each model was simulated for 10 oscillation cycles. Results show that relevant features of the laryngeal flow field, such as glottal jet deflection, develop even when applying rather simple static models with oscillating flow rates. Including further phonatory components such as vocal fold motion, mucosal wave propagation, and ventricular folds, the simulations show phonatory key features like intraglottal flow separation and increased flow rate in presence of ventricular folds. The simulation time on 100 CPU cores ranged between 25 and 290 hours, currently restricting clinical application of these models. Nevertheless, results show high potential of numerical simulations for better understanding of phonatory process. Copyright © 2018 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  16. An Immersed-Boundary Method for Fluid-Structure Interaction in the Human Larynx

    NASA Astrophysics Data System (ADS)

    Luo, Haoxiang; Zheng, Xudong; Mittal, Rajat; Bielamowicz, Steven

    2006-11-01

    We describe a novel and accurate computational methodology for modeling the airflow and vocal fold dynamics in human larynx. The model is useful in helping us gain deeper insight into the complicated bio-physics of phonation, and may have potential clinical application in design and placement of synthetic implant in vocal fold surgery. The numerical solution of the airflow employs a previously developed immersed-boundary solver. However, in order to incorporate the vocal fold into the model, we have developed a new immersed-boundary method that can simulate the dynamics of the multi-layered, viscoelastic solids. In this method, a finite-difference scheme is used to approximate the derivatives and ghost cells are defined near the boundary. To impose the traction boundary condition, a third-order polynomial is obtained using the weighted least squares fitting to approximate the function locally. Like its analogue for the flow solver, this immersed-boundary method for the solids has the advantage of simple grid generation, and may be easily implemented on parallel computers. In the talk, we will present the simulation results on both the specified vocal fold motion and the flow-induced vocal fold vibration. Supported by NIDCD Grant R01 DC007125-01A1.

  17. The role of finite displacements in vocal fold modeling.

    PubMed

    Chang, Siyuan; Tian, Fang-Bao; Luo, Haoxiang; Doyle, James F; Rousseau, Bernard

    2013-11-01

    Human vocal folds experience flow-induced vibrations during phonation. In previous computational models, the vocal fold dynamics has been treated with linear elasticity theory in which both the strain and the displacement of the tissue are assumed to be infinitesimal (referred to as model I). The effect of the nonlinear strain, or geometric nonlinearity, caused by finite displacements is yet not clear. In this work, a two-dimensional model is used to study the effect of geometric nonlinearity (referred to as model II) on the vocal fold and the airflow. The result shows that even though the deformation is under 1 mm, i.e., less than 10% of the size of the vocal fold, the geometric nonlinear effect is still significant. Specifically, model I underpredicts the gap width, the flow rate, and the impact stress on the medial surfaces as compared to model II. The study further shows that the differences are caused by the contact mechanics and, more importantly, the fluid-structure interaction that magnifies the error from the small-displacement assumption. The results suggest that using the large-displacement formulation in a computational model would be more appropriate for accurate simulations of the vocal fold dynamics.

  18. Dependencies and Ill-designed Parameters Within High-speed Videoendoscopy and Acoustic Signal Analysis.

    PubMed

    Schlegel, Patrick; Stingl, Michael; Kunduk, Melda; Kniesburges, Stefan; Bohr, Christopher; Döllinger, Michael

    2018-05-31

    The phonatory process is often judged during sustained phonation by analyzing the acoustic voice signal and the vocal fold vibrations. Many formulas and parameters have been suggested for qualifying the characteristics of the acoustic signal and the vocal fold vibrations during sustained phonation. These parameters are directly computed from the acoustic signal and the endoscopic glottal area waveform (GAW). The GAW is calculated from laryngeal high-speed videoendoscopy (HSV) recordings and describes the increase and decrease of the glottal area during the phonation process, that is, the opening and closing of the two oscillating vocal folds over time. However, some of the parameters have strong mathematical dependencies with one another and some are ill-defined. The purpose of this study is to identify mathematical dependencies between parameters with the aim of reducing their numbers and suggesting which parameters may best describe the properties of the GAW and the acoustical signal. In this preliminary investigation, 20 frequently used parameters are examined: 10 GAW only and 10 both GAW and acoustic parameters. In total 13 parameters can be neglected because of mathematical dependencies. In addition, nine of these parameters show problematic features that range from unexpected behavior to ill definition. Reducing the number of parameters appears to be necessary to standardize vocal fold function analysis. This may lead to better comparability of research results from different studies. Copyright © 2018 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  19. Fundamental frequency, phonation maximum time and vocal complaints in morbidly obese women

    PubMed Central

    de SOUZA, Lourdes Bernadete Rocha; PEREIRA, Rayane Medeiros; dos SANTOS, Marquiony Marques; GODOY, Cynthia Meida de Almeida

    2014-01-01

    Background Obese people have abnormal deposition of fat in the vocal tract that can interfere with the acoustic voice. Aim To relate the fundamental frequency, the maximum phonation time and voice complaints from a group of morbidly obese women. Methods Observational, cross-sectional and descriptive study that included 44 morbidly obese women, mean age of 42.45 (±10.31) years old, observational group and 30 women without obesity, control group, with 33.79 (±4.51)years old. The voice recording was done in a quiet environment, on a laptop using the program ANAGRAF acoustic analysis of speech sounds. To extract the values ​​of fundamental frequency the subjects were asked to produce vowel [a] at usual intensity for a period in average of three seconds. After the voice recording, participants were prompted to produce sustained vowel [ a] , [ i] and [ u] at usual intensity and height, using a stopwatch to measure the time that each participant could hold each vowel. Results The majority, 31(70.5%), had vocal complaints, with a higher percentage for complaints of vocal fatigue 20(64.51%) and voice failures 19(61.29%) followed by dryness of the throat in 15 (48.38%) and effort to speak 13(41.93%). There was no statistically significant difference regarding the mean fundamental frequency of the voice in both groups, but there was significance between the two groups regarding maximum phonation. Conclusion Increased adipose tissue in the vocal tract interfered in the vocal parameters. PMID:24676298

  20. Gender differences in children's voice use in a day care environment.

    PubMed

    Nygren, Mariana; Tyboni, Mikaela; Lindström, Fredric; McAllister, Anita; van Doorn, Jan

    2012-11-01

    The prevalence of dysphonia is higher in boys than in girls before puberty. This could be because of the differences in boys' and girls' voice use. Previous research on gender differences in prepubescent children's voice parameters has been contradictory. Most studies have focused on examining fundamental frequency. The purpose of this study was to investigate voice use in boys and girls in a day care environment based on the voice parameters fundamental frequency (Hz), vocal intensity (dB SPL), and phonation time (%) and to ascertain whether there were any significant gender differences. Prospective comparative design. The study was conducted in a day care environment where 30 children (17 boys and 13 girls aged 4-5 years) participated. The participants' voices were measured continuously for 4 hours with a voice accumulator that registered fundamental frequency, vocal intensity level, phonation time, and background noise. Mean (standard deviation) fundamental frequency was 310 (22) and 321 (16) Hz, vocal intensity was 93 (4) and 91 (3) dB SPL, and phonation time was 7.7 (2.0)% and 7.6 (2.5)% for boys and girls, respectively. No differences between genders were statistically significant. The finding of no statistically significant gender differences for measurements of voice parameters in a group of children aged 4-5 years in a day care environment is an important finding that contributes to increased knowledge about young boys' and girls' voice use. Copyright © 2012 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  1. A Mechanism for Frequency Modulation in Songbirds Shared with Humans

    PubMed Central

    Margoliash, Daniel

    2013-01-01

    In most animals that vocalize, control of fundamental frequency is a key element for effective communication. In humans, subglottal pressure controls vocal intensity but also influences fundamental frequency during phonation. Given the underlying similarities in the biomechanical mechanisms of vocalization in humans and songbirds, songbirds offer an attractive opportunity to study frequency modulation by pressure. Here, we present a novel technique for dynamic control of subsyringeal pressure in zebra finches. By regulating the opening of a custom-built fast valve connected to the air sac system, we achieved partial or total silencing of specific syllables, and could modify syllabic acoustics through more complex manipulations of air sac pressure. We also observed that more nuanced pressure variations over a limited interval during production of a syllable concomitantly affected the frequency of that syllable segment. These results can be explained in terms of a mathematical model for phonation that incorporates a nonlinear description for the vocal source capable of generating the observed frequency modulations induced by pressure variations. We conclude that the observed interaction between pressure and frequency was a feature of the source, not a result of feedback control. Our results indicate that, beyond regulating phonation or its absence, regulation of pressure is important for control of fundamental frequencies of vocalizations. Thus, although there are separate brainstem pathways for syringeal and respiratory control of song production, both can affect airflow and frequency. We hypothesize that the control of pressure and frequency is combined holistically at higher levels of the vocalization pathways. PMID:23825417

  2. Body mass index and acoustic voice parameters: is there a relationship.

    PubMed

    Souza, Lourdes Bernadete Rocha de; Santos, Marquiony Marques Dos

    2017-05-06

    Specific elements such as weight and body volume can interfere in voice production and consequently in its acoustic parameters, which is why it is important for the clinician to be aware of these relationships. To investigate the relationship between body mass index and the average acoustic voice parameters. Observational, cross-sectional descriptive study. The sample consisted of 84 women, aged between 18 and 40years, an average of 26.83 (±6.88). The subjects were grouped according to body mass index: 19 underweight; 23 normal ranges, 20 overweight and 22 obese and evaluated the fundamental frequency of the sustained vowel [a] and the maximum phonation time of the vowels [a], [i], [u], using PRAAT software. The data were submitted to the Kruskal-Wallis test to verify if there were differences between the groups regarding the study variables. All variables showed statistically significant results and were subjected to non-parametric test Mann-Whitney. Regarding to the average of the fundamental frequency, there was statistically significant difference between groups with underweight and overweight and obese; normal range and overweight and obese. The average maximum phonation time revealed statistically significant difference between underweight and obese individuals; normal range and obese; overweight and obese. Body mass index influenced the average fundamental frequency of overweight and obese individuals evaluated in this study. Obesity influenced in reducing maximum phonation time average. Copyright © 2017 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved.

  3. A mechanism for frequency modulation in songbirds shared with humans.

    PubMed

    Amador, Ana; Margoliash, Daniel

    2013-07-03

    In most animals that vocalize, control of fundamental frequency is a key element for effective communication. In humans, subglottal pressure controls vocal intensity but also influences fundamental frequency during phonation. Given the underlying similarities in the biomechanical mechanisms of vocalization in humans and songbirds, songbirds offer an attractive opportunity to study frequency modulation by pressure. Here, we present a novel technique for dynamic control of subsyringeal pressure in zebra finches. By regulating the opening of a custom-built fast valve connected to the air sac system, we achieved partial or total silencing of specific syllables, and could modify syllabic acoustics through more complex manipulations of air sac pressure. We also observed that more nuanced pressure variations over a limited interval during production of a syllable concomitantly affected the frequency of that syllable segment. These results can be explained in terms of a mathematical model for phonation that incorporates a nonlinear description for the vocal source capable of generating the observed frequency modulations induced by pressure variations. We conclude that the observed interaction between pressure and frequency was a feature of the source, not a result of feedback control. Our results indicate that, beyond regulating phonation or its absence, regulation of pressure is important for control of fundamental frequencies of vocalizations. Thus, although there are separate brainstem pathways for syringeal and respiratory control of song production, both can affect airflow and frequency. We hypothesize that the control of pressure and frequency is combined holistically at higher levels of the vocalization pathways.

  4. Comparison of voice-use profiles between elementary classroom and music teachers.

    PubMed

    Morrow, Sharon L; Connor, Nadine P

    2011-05-01

    Among teachers, music teachers are roughly four times more likely than classroom teachers to develop voice-related problems. Although it has been established that music teachers use their voices at high intensities and durations in the course of their workday, voice-use profiles concerning the amount and intensity of vocal use and vocal load have neither been quantified nor has vocal load for music teachers been compared with classroom teachers using these same voice-use parameters. In this study, total phonation time, fundamental frequency (F₀), and vocal intensity (dB SPL [sound pressure level]) were measured or estimated directly using a KayPENTAX Ambulatory Phonation Monitor (KayPENTAX, Lincoln Park, NJ). Vocal load was calculated as cycle and distance dose, as defined by Švec et al (2003), which integrates total phonation time, F₀, and vocal intensity. Twelve participants (n = 7 elementary music teachers and n = 5 elementary classroom teachers) were monitored during five full teaching days of one workweek to determine average vocal load for these two groups of teachers. Statistically significant differences in all measures were found between the two groups (P < 0.05) with large effect sizes for all parameters. These results suggest that typical vocal loads for music teachers are substantially higher than those experienced by classroom teachers (P < 0.01). This study suggests that reducing vocal load may have immediate clinical and educational benefits in vocal health in music teachers. Copyright © 2011 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  5. The softest sound levels of the human voice in normal subjects.

    PubMed

    Šrámková, Hana; Granqvist, Svante; Herbst, Christian T; Švec, Jan G

    2015-01-01

    Accurate measurement of the softest sound levels of phonation presents technical and methodological challenges. This study aimed at (1) reliably obtaining normative data on sustained softest sound levels for the vowel [a:] at comfortable pitch; (2) comparing the results for different frequency and time weighting methods; and (3) refining the Union of European Phoniatricians' recommendation on allowed background noise levels for scientific and equipment manufacturers' purposes. Eighty healthy untrained participants (40 females, 40 males) were investigated in quiet rooms using a head-mounted microphone and a sound level meter at 30 cm distance. The one-second-equivalent sound levels were more stable and more representative for evaluating the softest sustained phonations than the fast-time-weighted levels. At 30 cm, these levels were in the range of 48-61 dB(C)/41-53 dB(A) for females and 49 - 64 dB(C)/35-53 dB(A) for males (5% to 95% quantile range). These ranges may serve as reference data in evaluating vocal normality. In order to reach a signal-to-noise ratio of at least 10 dB for more than 95% of the normal population, the background noise should be below 25 dB(A) and 38 dB(C), respectively, for the softest phonation measurements at 30 cm distance. For the A-weighting, this is 15 dB lower than the previously recommended value.

  6. An experimental investigation on the subcritical instability in plane Poieseuille flow

    NASA Technical Reports Server (NTRS)

    Nishioka, T.; Honda, S.; Kamibayashi, S.

    1981-01-01

    The relationship between the three dimensional properties of the fundamental flow of a plane Poieseuille flow and subcritical stability was studied. An S-T wave was introduced into the flow and the three dimensional development of the wave observed. Results indicate that: (1) the T-S wave has three dimensional properties which are synchronous with the fundamental flow, but there is damping at microamplitude; (2) when the amplitude reaches a certain threshold, subcritical instability and peak valley bifurcation occur simultaneously and a peak valley structure is formed; (3) this threshold depends to a great extent on the frequency; and (4) after the peak valley bifurcation there is a transition to a turbulent flow by the process of laminar flow collapse identical to that in Blasius flow.

  7. Linking the micro and macro: L-H transition dynamics and threshold physics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Malkov, M. A., E-mail: mmalkov@ucsd.edu; Diamond, P. H.; Miki, K.

    2015-03-15

    The links between the microscopic dynamics and macroscopic threshold physics of the L → H transition are elucidated. Emphasis is placed on understanding the physics of power threshold scalings, and especially on understanding the minimum in the power threshold as a function of density P{sub thr} (n). By extending a numerical 1D model to evolve both electron and ion temperatures, including collisional coupling, we find that the decrease in P{sub thr} (n) along the low-density branch is due to the combination of an increase in collisional electron-to-ion energy transfer and an increase in the heating fraction coupled to the ions.more » Both processes strengthen the edge diamagnetic electric field needed to lock in the mean electric field shear for the L→H transition. The increase in P{sub thr} (n) along the high-density branch is due to the increase with ion collisionality of damping of turbulence-driven shear flows. Turbulence driven shear flows are needed to trigger the transition by extracting energy from the turbulence. Thus, we identify the critical transition physics components of the separatrix ion heat flux and the zonal flow excitation. The model reveals a power threshold minimum in density scans as a crossover between the threshold decrease supported by an increase in heat fraction received by ions (directly or indirectly, from electrons) and a threshold increase, supported by the rise in shear flow damping. The electron/ion heating mix emerges as important to the transition, in that it, together with electron-ion coupling, regulates the edge diamagnetic electric field shear. The importance of possible collisionless electron-ion heat transfer processes is explained.« less

  8. Objective definition of rainfall intensity-duration thresholds for post-fire flash floods and debris flows in the area burned by the Waldo Canyon fire, Colorado, USA

    USGS Publications Warehouse

    Staley, Dennis M.; Gartner, Joseph E.; Kean, Jason W.

    2015-01-01

    We present an objectively defined rainfall intensity-duration (I-D) threshold for the initiation of flash floods and debris flows for basins recently burned in the 2012 Waldo Canyon fire near Colorado Springs, Colorado, USA. Our results are based on 453 rainfall records which include 8 instances of hazardous flooding and debris flow from 10 July 2012 to 14 August 2013. We objectively defined the thresholds by maximizing the number of correct predictions of debris flow or flood occurrence while minimizing the rate of both Type I (false positive) and Type II (false negative) errors. The equation I = 11.6D−0.7 represents the I-D threshold (I, in mm/h) for durations (D, in hours) ranging from 0.083 h (5 min) to 1 h for basins burned by the 2012 Waldo Canyon fire. As periods of high-intensity rainfall over short durations (less than 1 h) produced all of the debris flow and flood events, real-time monitoring of rainfall conditions will result in very short lead times for early-warning. Our results highlight the need for improved forecasting of the rainfall rates during short-duration, high-intensity convective rainfall events.

  9. Hillslope threshold response to rainfall: (1) a field based forensic approach

    Treesearch

    Chris B. Graham; Ross A. Woods; Jeffrey J. McDonnell

    2010-01-01

    Hillslope threshold response to storm rainfall is poorly understood. Basic questions regarding the type, location, and flow dynamics of lateral, subsurface flow remain unanswered, even at our most intensively studied field sites. Here we apply a forensic approach where we combined irrigation and excavation experiments at the well studied Maimai hillslope to determine...

  10. Flow Glottogram Characteristics and Perceived Degree of Phonatory Pressedness.

    PubMed

    Millgård, Moa; Fors, Tobias; Sundberg, Johan

    2016-05-01

    Phonatory pressedness is a clinically relevant aspect of voice, which generally is analyzed by auditory perception. The present investigation aimed at identifying voice source and formant characteristics related to experts' ratings of phonatory pressedness. Experimental study of the relations between visual analog scale ratings of phonatory pressedness and voice source parameters in healthy voices. Audio, electroglottogram, and subglottal pressure, estimated from oral pressure during /p/ occlusion, were recorded from five female and six male subjects, each of whom deliberately varied phonation type between neutral, flow, and pressed in the syllable /pae/, produced at three loudness levels and three pitches. Speech-language pathologists rated, along a visual analog scale, the degree of perceived phonatory pressedness in these samples. The samples were analyzed by means of inverse filtering with regard to closed quotient, dominance of the voice source fundamental, normalized amplitude quotient, peak-to-peak flow amplitude, as well as formant frequencies and the alpha ratio of spectrum energy above and below 1000 Hz. The results were compared with the rating data, which showed that the ratings were closely related to voice source parameters. Approximately, 70% of the variance of the ratings could be explained by the voice source parameters. A multiple linear regression analysis suggested that perceived phonatory pressedness is related most closely to subglottal pressure, closed quotient, and the two lowest formants. Copyright © 2016 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  11. Benefits and limitations of using the weather radar for the definition of rainfall thresholds for debris flows. Case study from Catalonia (Spain).

    NASA Astrophysics Data System (ADS)

    Abancó, C.; Hürlimann, M.; Sempere, D.; Berenguer, M.

    2012-04-01

    Torrential processes such as debris flows or hyperconcentrated flows are fast movements formed by a mix of water and different amounts of unsorted solid material. They occur in steep torrents and suppose a high risk for the human settlements. Rainfall is the most common triggering factor for debris flows. The rainfall threshold defines the rainfall conditions that, when reached or exceeded, are likely to provoke one or more events. Many different types of empirical rainfall thresholds for landslide triggering have been defined. Direct measurements of rainfall data are normally not available from a point next to or in the surroundings of the initiation area of the landslide. For this reason, most of the thresholds published for debris flows have been established by data measured at the nearest rain gauges (often located several km far from the landslide). Only in very few cases, the rainfall data to analyse the triggering conditions of the debris flows have been obtained by weather (Doppler) radar. Radar devices present certain limitations in mountainous regions due to undesired reboots, but their main advantage is that radar data can be obtained for any point of the territory. The objective of this work was to test the use of the weather radar data for the definition of rainfall thresholds for debris-flow triggering. Thus, rainfall data obtained from 3 to 5 rain gauges and from radar were compared for a dataset of events occurred in Catalonia (Spain). The goal was to determine in which cases the description of the rainfall episode (in particular the maximum intensity) had been more accurate. The analysed dataset consists of: 1) three events occurred in the Rebaixader debris-flow monitoring station (Axial Pyrenees) including two hyperconcentrated flows and one debris flow; 2) one debris-flow event occurred in the Port Ainé ski resort (Axial Pyrenees); 3) one debris-flow event in Montserrat (Mediterranean Coastal range). The comparison of the hyetographs from the different devices showed that the reliability of the radar is higher for short, high intensity storms more than for long lasting, medium intensity ones. Additionally, the best fit corresponds to the situations where the storm nucleus is located near the source area of the debris flow. The results of the comparison between different rain gauges show similar trends. The ones located in the same valley as the debris flow usually show good results, but if there are orographic elements in-between the debris-flow torrent and the rain gauge or the distance is large, the results can imply a great error in the definition of rainfall intensity. Therefore, we can state that the reliability of the use of the weather radar to define rainfall thresholds is strongly depending on the type of the storm and the distance between the source area and the nucleus of the storm.

  12. Coupled prediction of flash flood response and debris flow occurrence: Application on an alpine extreme flood event

    NASA Astrophysics Data System (ADS)

    Destro, Elisa; Amponsah, William; Nikolopoulos, Efthymios I.; Marchi, Lorenzo; Marra, Francesco; Zoccatelli, Davide; Borga, Marco

    2018-03-01

    The concurrence of flash floods and debris flows is of particular concern, because it may amplify the hazard corresponding to the individual generative processes. This paper presents a coupled modelling framework for the predictions of flash flood response and of the occurrence of debris flows initiated by channel bed mobilization. The framework combines a spatially distributed flash flood response model and a debris flow initiation model to define a threshold value for the peak flow which permits identification of channelized debris flow initiation. The threshold is defined over the channel network as a function of the upslope area and of the local channel bed slope, and it is based on assumptions concerning the properties of the channel bed material and of the morphology of the channel network. The model is validated using data from an extreme rainstorm that impacted the 140 km2 Vizze basin in the Eastern Italian Alps on August 4-5, 2012. The results show that the proposed methodology has improved skill in identifying the catchments where debris-flows are triggered, compared to the use of simpler thresholds based on rainfall properties.

  13. Identifying Turbulent Structures through Topological Segmentation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bremer, Peer-Timo; Gruber, Andrea; Bennett, Janine C.

    2016-01-01

    A new method of extracting vortical structures from a turbulent flow is proposed whereby topological segmentation of an indicator function scalar field is used to identify the regions of influence of the individual vortices. This addresses a long-standing challenge in vector field topological analysis: indicator functions commonly used produce a scalar field based on the local velocity vector field; reconstructing regions of influence for a particular structure requires selecting a threshold to define vortex extent. In practice, the same threshold is rarely meaningful throughout a given flow. By also considering the topology of the indicator field function, the characteristics ofmore » vortex strength and extent can be separated and the ambiguity in the choice of the threshold reduced. The proposed approach is able to identify several types of vortices observed in a jet in cross-flow configuration simultaneously where no single threshold value for a selection of common indicator functions appears able to identify all of these vortex types.« less

  14. The putative involvement of the transabdominal muscles in dysphonia: a preliminary study and thoughts.

    PubMed

    Rubin, J S; Macdonald, I; Blake, E

    2011-03-01

    Real-time ultrasound was used as an adjunct to assess patterns of periabdominal musculature in 14 individual with dysphonia and muscle tension dysphonia. Fourteen individuals with muscle tension dysphonia were evaluated with real-time ultrasound as a part of their initial evaluation and management. In 13 of 14 individuals, there was an imbalance found during phonation between the transversus abdominis muscles (TAs) and internal oblique muscles (IOs), whereby the IOs were found to be overactive and the TAs underactive. After physiotherapy, this pattern was reversed. The abdominal muscle pattern of overactivity of the internal oblique and underactivity of the TA during phonation was found to be present in the large majority of patients in this pilot sample who had presented with muscle tension dysphonia. The significance of this is unclear but deserves further review. Copyright © 2011 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  15. Electroglottogram waveform types.

    PubMed

    Painter, C

    1988-01-01

    Electroglottography is a useful, non-invasive technique that can assist in the assessment of vocal fold dysfunction. However, if it is to become a useful clinical tool, there is a need for normative studies of the electroglottogram waveform types that characterize trained professional voice users, untrained non-professional speakers and patients with voice disorders and for a way of quantifying and objectively comparing similarities and differences. This report describes our methodology and an investigation into the waveform types characterizing one trained professional voice user phonating in 15 experimental sessions under various fundamental frequency, intensity and voice quality conditions. A number of strong tendencies were noted. In normal voice the lower frequencies and intensities represent one pole of a scale of a mode of phonation, while the higher frequencies and intensities depict the other pole. In these studies breathy voice data overlapped the lower end of the scale and tense voice data overlapped the upper end.

  16. [Fundamental frequency analysis - a contribution to the objective examination of the speaking and singing voice (author's transl)].

    PubMed

    Schultz-Coulon, H J

    1975-07-01

    The applicability of a newly developed fundamental frequency analyzer to diagnosis in phoniatrics is reviewed. During routine voice examination, the analyzer allows a quick and accurate measurement of fundamental frequency and sound level of the speaking voice, and of vocal range and maximum phonation time. By computing fundamental frequency histograms, the median fundamental frequency and the total pitch range can be better determined and compared. Objective studies of certain technical faculties of the singing voice, which usually are estimated subjectively by the speech therapist, may now be done by means of this analyzer. Several examples demonstrate the differences between correct and incorrect phonation. These studies compare the pitch perturbations during the crescendo and decrescendo of a swell-tone, and show typical traces of staccato, thrill and yodel. Conclusions of the study indicate that fundamental frequency analysis is a valuable supplemental method for objective voice examination.

  17. Effects of voice training and voice hygiene education on acoustic and perceptual speech parameters and self-reported vocal well-being in female teachers.

    PubMed

    Ilomaki, Irma; Laukkanen, Anne-Maria; Leppanen, Kirsti; Vilkman, Erkki

    2008-01-01

    Voice education programs may help in optimizing teachers' voice use. This study compared effects of voice training (VT) and voice hygiene lecture (VHL) in 60 randomly assigned female teachers. All 60 attended the lecture, and 30 completed a short training course in addition. Text reading was recorded in working environments and analyzed for fundamental frequency (F0), equivalent sound level (Leq), alpha ratio, jitter, shimmer, and perceptual quality. Self-reports of vocal well-being were registered. In the VHL group, increased F0 and difficulty of phonation and in the VT group decreased perturbation, increased alpha ratio, easier phonation, and improved perceptual and self-reported voice quality were found. Both groups equally self-reported increase of voice care knowledge. Results seem to indicate improved vocal well-being after training.

  18. Holes in the Bathtub: Water Table Dependent Services and Threshold Behavior in an Economic Model of Groundwater Extraction

    NASA Astrophysics Data System (ADS)

    Kirk-lawlor, N. E.; Edwards, E. C.

    2012-12-01

    In many groundwater systems, the height of the water table must be above certain thresholds for some types of surface flow to exist. Examples of flows that depend on water table elevation include groundwater baseflow to river systems, groundwater flow to wetland systems, and flow to springs. Meeting many of the goals of sustainable water resource management requires maintaining these flows at certain rates. Water resource management decisions invariably involve weighing tradeoffs between different possible usage regimes and the economic consequences of potential management choices are an important factor in these tradeoffs. Policies based on sustainability may have a social cost from forgoing present income. This loss of income may be worth bearing, but should be well understood and carefully considered. Traditionally, the economic theory of groundwater exploitation has relied on the assumption of a single-cell or "bathtub" aquifer model, which offers a simple means to examine complex interactions between water user and hydrologic system behavior. However, such a model assumes a closed system and does not allow for the simulation of groundwater outflows that depend on water table elevation (e.g. baseflow, springs, wetlands), even though those outflows have value. We modify the traditional single-cell aquifer model by allowing for outflows when the water table is above certain threshold elevations. These thresholds behave similarly to holes in a bathtub, where the outflow is a positive function of the height of the water table above the threshold and the outflow is lost when the water table drops below the threshold. We find important economic consequences to this representation of the groundwater system. The economic value of services provided by threshold-dependent outflows (including non-market value), such as ecosystem services, can be incorporated. The value of services provided by these flows may warrant maintaining the water table at higher levels than would be the case if only the benefits and costs of groundwater extraction were considered. This hole-in-the-bathtub model can motivate managers to consider the costs of the loss of such flows, which may be very costly (in terms of loss of environmental services, loss of access to surface water, etc.). Alternatively, the decision to maintain the water table at an elevation that sustains a threshold-dependent outflow may cause income loss from the imposition of lower groundwater extraction rates. Weighing the benefits of maintaining threshold-dependent flows (including non-market benefits) with the net benefits of increased extraction is an important step in a prudent water management framework. To illustrate the usefulness of the modified model in a joint economic-hydrologic context, we provide a short case study of the Ojos de San Pedro area of the Rio Loa Basin in northern Chile. Evidence indicates that a wetland and lacustrine environment and a village dependent on that environment disappeared due to water extraction for industrial use. We demonstrate how the key features of the model provide important insight in understanding the tradeoffs that were made in this case.

  19. Physical context for theoretical approaches to sediment transport magnitude-frequency analysis in alluvial channels

    NASA Astrophysics Data System (ADS)

    Sholtes, Joel; Werbylo, Kevin; Bledsoe, Brian

    2014-10-01

    Theoretical approaches to magnitude-frequency analysis (MFA) of sediment transport in channels couple continuous flow probability density functions (PDFs) with power law flow-sediment transport relations (rating curves) to produce closed-form equations relating MFA metrics such as the effective discharge, Qeff, and fraction of sediment transported by discharges greater than Qeff, f+, to statistical moments of the flow PDF and rating curve parameters. These approaches have proven useful in understanding the theoretical drivers behind the magnitude and frequency of sediment transport. However, some of their basic assumptions and findings may not apply to natural rivers and streams with more complex flow-sediment transport relationships or management and design scenarios, which have finite time horizons. We use simple numerical experiments to test the validity of theoretical MFA approaches in predicting the magnitude and frequency of sediment transport. Median values of Qeff and f+ generated from repeated, synthetic, finite flow series diverge from those produced with theoretical approaches using the same underlying flow PDF. The closed-form relation for f+ is a monotonically increasing function of flow variance. However, using finite flow series, we find that f+ increases with flow variance to a threshold that increases with flow record length. By introducing a sediment entrainment threshold, we present a physical mechanism for the observed diverging relationship between Qeff and flow variance in fine and coarse-bed channels. Our work shows that through complex and threshold-driven relationships sediment transport mode, channel morphology, flow variance, and flow record length all interact to influence estimates of what flow frequencies are most responsible for transporting sediment in alluvial channels.

  20. The Effect of Anchors and Training on the Reliability of Voice Quality Ratings for Different Types of Speech Stimuli.

    PubMed

    Brinca, Lilia; Batista, Ana Paula; Tavares, Ana Inês; Pinto, Patrícia N; Araújo, Lara

    2015-11-01

    The main objective of the present study was to investigate if the type of voice stimuli-sustained vowel, oral reading, and connected speech-results in good intrarater and interrater agreement/reliability. A short-term panel study was performed. Voice samples from 30 native European Portuguese speakers were used in the present study. The speech materials used were (1) the sustained vowel /a/, (2) oral reading of the European Portuguese version of "The Story of Arthur the Rat," and (3) connected speech. After an extensive training with textual and auditory anchors, the judges were asked to rate the severity of dysphonic voice stimuli using the phonation dimensions G, R, and B from the GRBAS scale. The voice samples were judged 6 months and 1 year after the training. Intrarater agreement and reliability were generally very good for all the phonation dimensions and voice stimuli. The highest interrater reliability was obtained using the oral reading stimulus, particularly for phonation dimensions grade (G) and breathiness (B). Roughness (R) was the voice quality that was the most difficult to evaluate, leading to interrater unreliability in all voice quality ratings. Extensive training using textual and auditory anchors and the use of anchors during the voice evaluations appear to be good methods for auditory-perceptual evaluation of dysphonic voices. The best results of interrater reliability were obtained when the oral reading stimulus was used. Breathiness appears to be a voice quality that is easier to evaluate than roughness. Copyright © 2015 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  1. Esophageal Dysmotility in Patients following Total Laryngectomy.

    PubMed

    Zhang, Teng; Maclean, Julia; Szczesniak, Michal; Bertrand, Paul P; Quon, Harry; Tsang, Raymond K; Wu, Peter I; Graham, Peter; Cook, Ian J

    2018-02-01

    Objectives Dysphagia is common in total laryngectomees, with some symptoms suggesting esophageal dysmotility. Tracheoesophageal (TE) phonation requires effective esophagopharyngeal air passage. Hence, esophageal dysmotility may affect deglutition or TE phonation. This study aimed to determine (1) the characteristics of esophageal dysmotility in laryngectomees, (2) whether clinical history is sensitive in detecting esophageal dysmotility, and (3) the relationship between esophageal dysmotility and TE prosthesis dysfunction. Study Design Multidisciplinary cross-sectional study. Setting Tertiary academic hospital. Subjects and Methods For 31 participants undergone total laryngectomy 1 to 12 years prior, clinical histories were taken by a gastroenterologist and a speech pathologist experienced in managing dysphagia. Esophageal high-resolution manometry was performed and analyzed using Chicago Classification v3.0. Results Interpretable manometric studies were obtained in 23 (1 normal manometry). Esophageal dysmotility patterns included achalasia, esophagogastric junction outflow obstruction, diffuse esophageal spasm, and other major (30%) and minor (50%) peristaltic disorders. The sensitivity of predicting any esophageal dysmotility was 28%, but it is noteworthy that patients with achalasia and diffuse esophageal spasm (DES) were predicted. Two of 4 participants with TE puncture leakage had poor esophageal clearance. Of 20 TE speakers, 12 had voice problems, no correlation between poor voice, and any dysmotility pattern. Conclusions Peristaltic and lower esophageal sphincter dysfunction are common in laryngectomees. Clinical history, while not predictive of minor motor abnormalities, predicted correctly cases with treatable spastic motor disorders. Dysmotility was not associated with poor phonation, although TE puncture leakage might be linked to poor esophageal clearance. Esophageal dysmotility should be considered in the laryngectomees with persisting dysphagia or leaking TE puncture.

  2. Voice Use Among Music Theory Teachers: A Voice Dosimetry and Self-Assessment Study.

    PubMed

    Schiller, Isabel S; Morsomme, Dominique; Remacle, Angélique

    2017-07-25

    This study aimed (1) to investigate music theory teachers' professional and extra-professional vocal loading and background noise exposure, (2) to determine the correlation between vocal loading and background noise, and (3) to determine the correlation between vocal loading and self-evaluation data. Using voice dosimetry, 13 music theory teachers were monitored for one workweek. The parameters analyzed were voice sound pressure level (SPL), fundamental frequency (F0), phonation time, vocal loading index (VLI), and noise SPL. Spearman correlation was used to correlate vocal loading parameters (voice SPL, F0, and phonation time) and noise SPL. Each day, the subjects self-assessed their voice using visual analog scales. VLI and self-evaluation data were correlated using Spearman correlation. Vocal loading parameters and noise SPL were significantly higher in the professional than in the extra-professional environment. Voice SPL, phonation time, and female subjects' F0 correlated positively with noise SPL. VLI correlated with self-assessed voice quality, vocal fatigue, and amount of singing and speaking voice produced. Teaching music theory is a profession with high vocal demands. More background noise is associated with increased vocal loading and may indirectly increase the risk for voice disorders. Correlations between VLI and self-assessments suggest that these teachers are well aware of their vocal demands and feel their effect on voice quality and vocal fatigue. Visual analog scales seem to represent a useful tool for subjective vocal loading assessment and associated symptoms in these professional voice users. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  3. Impact of auditory training for perceptual assessment of voice executed by undergraduate students in Speech-Language Pathology.

    PubMed

    Silva, Regiane Serafim Abreu; Simões-Zenari, Marcia; Nemr, Nair Kátia

    2012-01-01

    To analyze the impact of auditory training for auditory-perceptual assessment carried out by Speech-Language Pathology undergraduate students. During two semesters, 17 undergraduate students enrolled in theoretical subjects regarding phonation (Phonation/Phonation Disorders) analyzed samples of altered and unaltered voices (selected for this purpose), using the GRBAS scale. All subjects received auditory training during nine 15-minute meetings. In each meeting, a different parameter was presented using the different voices sample, with predominance of the trained aspect in each session. Sample assessment using the scale was carried out before and after training, and in other four opportunities throughout the meetings. Students' assessments were compared to an assessment carried out by three voice-experts speech-language pathologists who were the judges. To verify training effectiveness, the Friedman's test and the Kappa index were used. The rate of correct answers in the pre-training was considered between regular and good. It was observed maintenance of the number of correct answers throughout assessments, for most of the scale parameters. In the post-training moment, the students showed improvements in the analysis of asthenia, a parameter that was emphasized during training after the students reported difficulties analyzing it. There was a decrease in the number of correct answers for the roughness parameter after it was approached segmented into hoarseness and harshness, and observed in association with different diagnoses and acoustic parameters. Auditory training enhances students' initial abilities to perform the evaluation, aside from guiding adjustments in the dynamics of the university subject.

  4. Objective Identification of Prepubertal Female Singers and Non-singers by Singing Power Ratio Using Matlab.

    PubMed

    Usha, M; Geetha, Y V; Darshan, Y S

    2017-03-01

    The field of music is increasingly gaining scope and attracting researchers from varied fields in terms of improvising the art of voice modulation in singing. There has been a lot of competition, and young budding singers are emerging with more talent. This study is aimed to develop software to differentiate a prepubertal voice as that of a singer or a non-singer using an objective tool-singing power ratio (SPR)-as an objective measure to quantify the resonant voice quality. Recordings of singing and phonation were obtained from 30 singers and 30 non-singer girls (8-10 years). Three professional singers perceptually evaluated all samples using a rating scale and categorized them as singers or non-singers. Using Matlab, a program was developed to automatically calculate the SPR of a particular sample and classify it into either of two groups based on the normative values of SPR developed manually. Positive correlation for SPR of phonation or singing was found between perceptual and manual ratings, and objective values of SPR. Software could automatically give the SPR values for samples that are fed and could further differentiate them as singer or non-singer. Researchers need not depend on professional singers or musicians for the judgment of voice for research purposes. This software uses an objective tool, which serves as an instrument to judge singing talent using singing and phonation samples of children. Also, it can be used as a first line of judgment in any singing audition process, which could ease the work of professionals. Copyright © 2017 The Voice Foundation. All rights reserved.

  5. The Effect of Fin Pitch on Fluid Elastic Instability of Tube Arrays Subjected to Cross Flow of Water

    NASA Astrophysics Data System (ADS)

    Desai, Sandeep Rangrao; Pavitran, Sampat

    2018-02-01

    Failure of tubes in shell and tube exchangers is attributed to flow induced vibrations of such tubes. There are different excitations mechanisms due to which flow induced vibration occurs and among such mechanisms, fluid elastic instability is the most prominent one as it causes the most violent vibrations and may lead to rapid tube failures within short time. Fluid elastic instability is the fluid-structure interaction phenomenon which occurs when energy input by the fluid force exceeds energy expended in damping. This point is referred as instability threshold and corresponding velocity is referred as critical velocity. Once flow velocity exceeds critical flow velocity, the vibration amplitude increases very rapidly with flow velocity. An experimental program is carried out to determine the critical velocity at instability for plain and finned tube arrays subjected to cross flow of water. The tube array geometry is parallel triangular with cantilever end condition and pitch ratios considered are 2.6 and 2.1. The objective of research is to determine the effect of increase in pitch ratio on instability threshold for plain tube arrays and to assess the effect of addition of fins as well as increase in fin density on instability threshold for finned tube arrays. Plain tube array with two different pitch ratios; 2.1 and 2.6 and finned tube arrays with same pitch ratio; 2.6 but with two different fin pitches; such as fine (10 fpi) and coarse (4 fpi) are considered for the experimentation. Connors' equation that relates critical velocity at instability to different parameters, on which instability depends, has been used as the basis for analysis and the concept of effective diameter is used for the present investigation. The modal parameters are first suitably modified using natural frequency reduction setup that is already designed and developed to reduce natural frequency and hence to achieve experimental simulation of fluid elastic instability within the limited flow capacity of the pump. The tests are carried out first on plain tube arrays to establish the same as the datum case and results are compared to known results of plain tube arrays and hence the quality of the test rig is also assessed. The fluid elastic vibration tests are then carried out on finned tube arrays with coarse and fine fin pitches and effects of fins and fin pitch on instability threshold are shown. The vibration response of the tube is recorded for each gradually increasing flow rates of water till instability point is reached. The parameters at the instability are then presented in terms of dimensionless parameters to compare them with published results. It is concluded that, arrays with higher pitch ratios are unstable at comparatively higher flow velocities and instability threshold for finned tube arrays is delayed due to addition of the fins. Further, it is concluded that, instability threshold for finned tube arrays with fine fin pitch is delayed compared to coarse fin pitch and hence for increased fin density, instability threshold is delayed. The experimental results in terms of critical velocities obtained for different tube arrays subjected to water cross flow will serve as the base flow rates for air-water cross flow experiments to be conducted in the next phase.

  6. Streamflow losses in the Black Hills of western South Dakota

    USGS Publications Warehouse

    Hortness, Jon E.; Driscoll, Daniel G.

    1998-01-01

    Losses occur in numerous streams that cross outcrops of various sedimentary rocks that are exposed around the periphery of the Black Hills of South Dakota. These streamflow losses are recognized as an important source of local recharge to regional bedrock aquifers. Most streams lose all of their flow up to some threshold rate. Streamflow is maintained through a loss zone when the threshold is exceeded. Streamflow records for 86 measurement sites are used to determine bedrock loss thresholds for 24 area streams, which have individual loss thresholds that range from negligible (no loss) to as much as 50 cubic feet per second. In addition, insights are provided regarding springflow that occurs in the immediate vicinity of selected loss zones. Most losses occur to outcrops of the Madison Limestone and Minnelusa Formation. Losses to the Deadwood Formation probably are minimal. Losses to the Minnekahta Limestone generally are small; however, they are difficult to quantify because of potential losses to extensive alluvial deposits that commonly are located near Minnekahta outcrops. Loss thresholds for each stream are shown to be relatively constant, without measurable effects from streamflow rates or duration of flow through the loss zones. Calculated losses for measurements made during high-flow conditions generally have larger variability than calculated losses for low-flow conditions; however, consistent relations between losses and streamflow have not been identified. Some of this variability results from the inability to account for tributary inflows and changes in storage. Calculated losses are shown to decrease, in some cases, during periods of extended flow through loss zones. Decreased 'net' losses, however, generally can be attributed to springflow (ground-water discharge) within a loss zone, which may occur during prolonged periods of wet climatic conditions. Losses to unsaturated alluvial deposits located adjacent to the stream channels are found to have significant effects on determination of bedrock losses. Large losses occur in filling initial storage in unsaturated alluvial deposits downstream from loss zones, when bedrock loss thresholds are first exceeded. Losses to alluvial deposits in the range of tens of cubic feet per second and alluvial storage capacities in the range of hundreds of acre-feet are documented. Significant changes in loss thresholds for Grace Coolidge Creek, Spring Creek, and Whitewood Creek are documented. Introduction of large quantities of fine-grained sediments into these stream channels may have affected loss thresholds for various periods of time.

  7. Flood disturbance and regrowth of vegetation in ephemeral channels: conditions and interactions

    NASA Astrophysics Data System (ADS)

    Hooke, J.

    2012-04-01

    Flood flows disturb vegetation growing in ephemeral channels but more information is needed on the thresholds for damage and removal and on the regrowth processes and timescales after floods. Once vegetation is re-established then it has feedback effects on processes and may raise thresholds. Several sites in SE Spain have been monitored for the effects of flows and for the growth and responses of plants over a period of >15 years. Two major floods and many minor flows have occurred. Measurements on quadrats and in different zones of the valley floor have allowed quantification of the thresholds for damage of different species of plant. Position of the plants in the channel also has a marked influence on effect of flows; velocities and flow forces for different parts have been calculated. The threshold for removal or mortality of certain plants in these Mediterranean valleys is very high. Types and species of plants regrowing in different zones have been identified and rates of growth measured. The relationship to climatic and weather conditions between channel flows is analysed. Growth rates between floods are closely related to moisture availability, mainly influenced by inter-annual variability of rainfall but also varying with location in the channel. One site in which hydrological regime was altered by human actions has shown marked change in vegetation cover and in channel response. Feedback effects reduce erosion and increase sedimentation and these effects have been measured directly and by calculation of roughness and resistance effects. The results demonstrate the different degrees of adaptation of plants to disturbance, natural vegetation such as phreatophytes showing high resilience but crop trees such as olives and almonds on floodplains being vulnerable to high flows.

  8. Transition to subcritical turbulence in a tokamak plasma

    NASA Astrophysics Data System (ADS)

    van Wyk, F.; Highcock, E. G.; Schekochihin, A. A.; Roach, C. M.; Field, A. R.; Dorland, W.

    2016-12-01

    Tokamak turbulence, driven by the ion-temperature gradient and occurring in the presence of flow shear, is investigated by means of local, ion-scale, electrostatic gyrokinetic simulations (with both kinetic ions and electrons) of the conditions in the outer core of the Mega-Ampere Spherical Tokamak (MAST). A parameter scan in the local values of the ion-temperature gradient and flow shear is performed. It is demonstrated that the experimentally observed state is near the stability threshold and that this stability threshold is nonlinear: sheared turbulence is subcritical, i.e. the system is formally stable to small perturbations, but, given a large enough initial perturbation, it transitions to a turbulent state. A scenario for such a transition is proposed and supported by numerical results: close to threshold, the nonlinear saturated state and the associated anomalous heat transport are dominated by long-lived coherent structures, which drift across the domain, have finite amplitudes, but are not volume filling; as the system is taken away from the threshold into the more unstable regime, the number of these structures increases until they overlap and a more conventional chaotic state emerges. Whereas this appears to represent a new scenario for transition to turbulence in tokamak plasmas, it is reminiscent of the behaviour of other subcritically turbulent systems, e.g. pipe flows and Keplerian magnetorotational accretion flows.

  9. Model for Predicting Passage of Invasive Fish Species Through Culverts

    NASA Astrophysics Data System (ADS)

    Neary, V.

    2010-12-01

    Conservation efforts to promote or inhibit fish passage include the application of simple fish passage models to determine whether an open channel flow allows passage of a given fish species. Derivations of simple fish passage models for uniform and nonuniform flow conditions are presented. For uniform flow conditions, a model equation is developed that predicts the mean-current velocity threshold in a fishway, or velocity barrier, which causes exhaustion at a given maximum distance of ascent. The derivation of a simple expression for this exhaustion-threshold (ET) passage model is presented using kinematic principles coupled with fatigue curves for threatened and endangered fish species. Mean current velocities at or above the threshold predict failure to pass. Mean current velocities below the threshold predict successful passage. The model is therefore intuitive and easily applied to predict passage or exclusion. The ET model’s simplicity comes with limitations, however, including its application only to uniform flow, which is rarely found in the field. This limitation is addressed by deriving a model that accounts for nonuniform conditions, including backwater profiles and drawdown curves. Comparison of these models with experimental data from volitional swimming studies of fish indicates reasonable performance, but limitations are still present due to the difficulty in predicting fish behavior and passage strategies that can vary among individuals and different fish species.

  10. Critical rainfall conditions for the initiation of torrential flows. Results from the Rebaixader catchment (Central Pyrenees)

    NASA Astrophysics Data System (ADS)

    Abancó, Clàudia; Hürlimann, Marcel; Moya, José; Berenguer, Marc

    2016-10-01

    Torrential flows like debris flows or debris floods are fast movements formed by a mix of water and different amounts of unsorted solid material. They generally occur in steep torrents and pose high risk in mountainous areas. Rainfall is their most common triggering factor and the analysis of the critical rainfall conditions is a fundamental research task. Due to their wide use in warning systems, rainfall thresholds for the triggering of torrential flows are an important outcome of such analysis and are empirically derived using data from past events. In 2009, a monitoring system was installed in the Rebaixader catchment, Central Pyrenees (Spain). Since then, rainfall data of 25 torrential flows (;TRIG rainfalls;) were recorded, with a 5-min sampling frequency. Other 142 rainfalls that did not trigger torrential flows (;NonTRIG rainfalls;) were also collected and analyzed. The goal of this work was threefold: (i) characterize rainfall episodes in the Rebaixader catchment and compare rainfall data that triggered torrential flows and others that did not; (ii) define and test Intensity-Duration (ID) thresholds using rainfall data measured inside the catchment by with different techniques; (iii) analyze how the criterion used for defining the rainfall duration and the spatial variability of rainfall influences the value obtained for the thresholds. The statistical analysis of the rainfall characteristics showed that the parameters that discriminate better the TRIG and NonTRIG rainfalls are the rainfall intensities, the mean rainfall and the total rainfall amount. The antecedent rainfall was not significantly different between TRIG and NonTRIG rainfalls, as it can be expected when the source material is very pervious (a sandy glacial soil in the study site). Thresholds were derived from data collected at one rain gauge located inside the catchment. Two different methods were applied to calculate the duration and intensity of rainfall: (i) using total duration, Dtot, and mean intensity, Imean, of the rainfall event, and (ii) using floating durations, D, and intensities, Ifl, based on the maximum values over floating periods of different duration. The resulting thresholds are considerably different (Imean = 6.20 Dtot-0.36 and Ifl_90% = 5.49 D-0.75, respectively) showing a strong dependence on the applied methodology. On the other hand, the definition of the thresholds is affected by several types of uncertainties. Data from both rain gauges and weather radar were used to analyze the uncertainty associated with the spatial variability of the triggering rainfalls. The analysis indicates that the precipitation recorded by the nearby rain gauges can introduce major uncertainties, especially for convective summer storms. Thus, incorporating radar rainfall can significantly improve the accuracy of the measured triggering rainfall. Finally, thresholds were also derived according to three different criteria for the definition of the duration of the triggering rainfall: (i) the duration until the peak intensity, (ii) the duration until the end of the rainfall; and, (iii) the duration until the trigger of the torrential flow. An important contribution of this work is the assessment of the threshold relationships obtained using the third definition of duration. Moreover, important differences are observed in the obtained thresholds, showing that ID relationships are significantly dependent on the applied methodology.

  11. Change in Pulmonary Function after Incentive Spirometer Exercise in Children with Spastic Cerebral Palsy: A Randomized Controlled Study.

    PubMed

    Choi, Ja Young; Rha, Dong-wook; Park, Eun Sook

    2016-05-01

    The aim of this study was to investigate the effect of incentive spirometer exercise (ISE) on pulmonary function and maximal phonation time (MPT) in children with spastic cerebral palsy (CP). Fifty children with CP were randomly assigned to two groups: the experimental group and the control group. Both groups underwent comprehensive rehabilitation therapy. The experimental group underwent additional ISE. The forced vital capacity (FVC), forced expiratory volume at one second (FEV₁), FEV₁/FVC ratio, peak expiratory flow (PEF), and MPT were assessed as outcome measures before and after 4 weeks of training. There were significant improvements in FVC, FEV₁, PEF, and MPT in the experimental group, but not in the control group. In addition, the improvements in FVC, FEV₁, and MPT were significantly greater in the experimental group than in the control group. The results of this randomized controlled study support the use of ISE for enhancing pulmonary function and breath control for speech production in children with CP.

  12. Negative Coulomb damping, limit cycles, and self-oscillation of the vocal folds

    NASA Astrophysics Data System (ADS)

    Fulcher, Lewis P.; Scherer, Ronald C.; Melnykov, Artem; Gateva, Vesela; Limes, Mark E.

    2006-05-01

    An effective one-mass model of phonation is developed. It borrows the salient features of the classic two-mass model of human speech developed by Ishizaka, Matsudaira, and Flanagan. Their model is based on the idea that the oscillating vocal folds maintain their motion by deriving energy from the flow of air through the glottis. We argue that the essence of the action of the aerodynamic forces on the vocal folds is captured by negative Coulomb damping, which acts on the oscillator to energize it. A viscous force is added to include the effects of tissue damping. The solutions to this single oscillator model show that when it is excited by negative Coulomb damping, it will reach a limit cycle. Displacements, phase portraits, and energy histories are presented for two underdamped linear oscillators. A nonlinear force is added so that the variations of the fundamental frequency and the open quotient with lung pressure are comparable to the behavior of the two-mass model.

  13. Anatomic Optical Coherence Tomography of Upper Airways

    NASA Astrophysics Data System (ADS)

    Chin Loy, Anthony; Jing, Joseph; Zhang, Jun; Wang, Yong; Elghobashi, Said; Chen, Zhongping; Wong, Brian J. F.

    The upper airway is a complex and intricate system responsible for respiration, phonation, and deglutition. Obstruction of the upper airways afflicts an estimated 12-18 million Americans. Pharyngeal size and shape are important factors in the pathogenesis of airway obstructions. In addition, nocturnal loss in pharyngeal muscular tone combined with high pharyngeal resistance can lead to collapse of the airway and periodic partial or complete upper airway obstruction. Anatomical optical coherence tomography (OCT) has the potential to provide high-speed three-dimensional tomographic images of the airway lumen without the use of ionizing radiation. In this chapter we describe the methods behind endoscopic OCT imaging and processing to generate full three dimensional anatomical models of the human airway which can be used in conjunction with numerical simulation methods to assess areas of airway obstruction. Combining this structural information with flow dynamic simulations, we can better estimate the site and causes of airway obstruction and better select and design surgery for patients with obstructive sleep apnea.

  14. Behavioural and neurobiological implications of linear and non-linear features in larynx phonations of horseshoe bats

    PubMed Central

    Kobayasi, Kohta I.; Hage, Steffen R.; Berquist, Sean; Feng, Jiang; Zhang, Shuyi; Metzner, Walter

    2012-01-01

    Mammalian vocalizations exhibit large variations in their spectrotemporal features, although it is still largely unknown which result from intrinsic biomechanical properties of the larynx and which are under direct neuromuscular control. Here we show that mere changes in laryngeal air flow yield several non-linear effects on sound production, in an isolated larynx preparation from horseshoe bats. Most notably, there are sudden jumps between two frequency bands used for either echolocation or communication in natural vocalizations. These jumps resemble changes in “registers” as in yodelling. In contrast, simulated contractions of the main larynx muscle produce linear frequency changes, but are limited to echolocation or communication frequencies. Only by combining non-linear and linear properties can this larynx therefore produce sounds covering the entire frequency range of natural calls. This may give behavioural meaning to yodelling-like vocal behaviour and reshape our thinking about how the brain controls the multitude of spectral vocal features in mammals. PMID:23149729

  15. Dynamic shear-stress-enhanced rates of nutrient consumption in gas-liquid semi-continuous-flow suspensions

    NASA Astrophysics Data System (ADS)

    Belfiore, Laurence A.; Volpato, Fabio Z.; Paulino, Alexandre T.; Belfiore, Carol J.

    2011-12-01

    The primary objective of this investigation is to establish guidelines for generating significant mammalian cell density in suspension bioreactors when stress-sensitive kinetics enhance the rate of nutrient consumption. Ultra-low-frequency dynamic modulations of the impeller (i.e., 35104 Hz) introduce time-dependent oscillatory shear into this transient analysis of cell proliferation under semi-continuous creeping flow conditions. Greater nutrient consumption is predicted when the amplitude A of modulated impeller rotation increases, and stress-kinetic contributions to nutrient consumption rates increase linearly at higher modulation frequency via an application of fluctuation-dissipation response. Interphase mass transfer is required to replace dissolved oxygen as it is consumed by aerobic nutrient consumption in the liquid phase. The theory and predictions described herein could be important at small length scales in the creeping flow regime where viscous shear is significant at the interface between the nutrient medium and isolated cells in suspension. Two-dimensional flow around spherically shaped mammalian cells, suspended in a Newtonian culture medium, is analyzed to calculate the surface-averaged magnitude of the velocity gradient tensor and modify homogeneous rates of nutrient consumption that are stimulated by viscous shear, via the formalism of stress-kinetic reciprocal relations that obey Curie's theorem in non-equilibrium thermodynamics. Time constants for stress-free free and stress-sensitive stress nutrient consumption are defined and quantified to identify the threshold (i.e., stress,threshold) below which the effect of stress cannot be neglected in accurate predictions of bioreactor performance. Parametric studies reveal that the threshold time constant for stress-sensitive nutrient consumption stress,threshold decreases when the time constant for stress-free nutrient consumption free is shorter. Hence, stress,threshold depends directly on free. In other words, the threshold rate of stress-sensitive nutrient consumption is higher when the stress-free rate of nutrient consumption increases. Modulated rotation of the impeller, superimposed on steady shear, increases stress,threshold when free is constant, and stress,threshold depends directly on the amplitude A of these angular velocity modulations.

  16. Self-oscillating Vocal Fold Model Mechanics: Healthy, Diseased, and Aging

    NASA Astrophysics Data System (ADS)

    Hiubler, Elizabeth P.; Pollok, Lucas F. E.; Apostoli, Adam G.; Hancock, Adrienne B.; Plesniak, Michael W.

    2014-11-01

    Voice disorders have been estimated to have a substantial economic impact of 2.5 billion annually. Approximately 30% of people will suffer from a voice disorder at some point in their lives. Life-sized, self-oscillating, synthetic vocal fold (VF) models are fabricated to exhibit material properties representative of human VFs. These models are created both with and without a polyp-like structure, a pathology that has been shown to produce rich viscous flow structures not normally observed for healthy VFs during normal phonation. Pressure measurements are acquired upstream of the VFs and high-speed images are captured at varying flow rates during VF oscillation to facilitate an understanding of the characteristics of healthy and diseased VFs. The images are analyzed using a videokymography line-scan technique. Clinically-relevant parameters calculated from the volume-velocity output of a circumferentially-vented mask (Rothenberg mask) are compared to human data collected from two groups of males aged 18-30 and 60-80. This study extends the use of synthetic VF models by assessing their ability to replicate behaviors observed in human subject data to advance a means of investigating changes associated with normal, pathological, and the aging voice. Supported by the GWU Institute for Biomedical Engineering (GWIBE) and GWU Center for Biomimetics and Bioinspired Engineering (COBRE).

  17. Formant and voice source properties in two male Kunqu Opera roles: a pilot study.

    PubMed

    Dong, Li; Sundberg, Johan; Kong, Jiangping

    2013-01-01

    This investigation analyzes flow glottogram and electroglottogram (EGG) parameters as well as the relationship between formant frequencies and partials in two male Kunqu Opera roles, Colorful face (CF) and Old man (OM). Four male professional Kunqu Opera singers volunteered as participants, 2 singers for each role. Using inverse filtering of the audio signal flow glottogram parameters and formant frequencies were measured in each note of scales. Two EGG parameters, contact quotient (CoQ) and speed quotient, were measured. Formant tuning was observed only in 1 of the OM singers and appeared in a pitch range lower than the passaggio range of Western male opera singers. Both the CF and the OM role singers showed high CoQ values and low values of the normalized amplitude quotient in singing. For 3 of the 4 singers CoQ and the level difference between the first and second partials showed a positive and a negative correlation with fundamental frequency (F0), respectively. Formant tuning may be applied by a singer of the OM role, and both CF and OM role singers may use a rather pressed type of phonation, CF singers more than OM singers in the lower part of the pitch range. Most singers increased glottal adduction with rising F0.

  18. Physical Linguistics.

    ERIC Educational Resources Information Center

    Tice, Bradley S.

    Physical linguistics is defined as the use of treatments from the field of speech pathology to enhance first and second language production in healthy individuals, resulting in increased quality and strength of phonation and articulation. A series of exercises for treating dysarthria (weakness, paralysis, discoordination, primary and secondary…

  19. Time-Dependent Computed Tomographic Perfusion Thresholds for Patients With Acute Ischemic Stroke.

    PubMed

    d'Esterre, Christopher D; Boesen, Mari E; Ahn, Seong Hwan; Pordeli, Pooneh; Najm, Mohamed; Minhas, Priyanka; Davari, Paniz; Fainardi, Enrico; Rubiera, Marta; Khaw, Alexander V; Zini, Andrea; Frayne, Richard; Hill, Michael D; Demchuk, Andrew M; Sajobi, Tolulope T; Forkert, Nils D; Goyal, Mayank; Lee, Ting Y; Menon, Bijoy K

    2015-12-01

    Among patients with acute ischemic stroke, we determine computed tomographic perfusion (CTP) thresholds associated with follow-up infarction at different stroke onset-to-CTP and CTP-to-reperfusion times. Acute ischemic stroke patients with occlusion on computed tomographic angiography were acutely imaged with CTP. Noncontrast computed tomography and magnectic resonance diffusion-weighted imaging between 24 and 48 hours were used to delineate follow-up infarction. Reperfusion was assessed on conventional angiogram or 4-hour repeat computed tomographic angiography. Tmax, cerebral blood flow, and cerebral blood volume derived from delay-insensitive CTP postprocessing were analyzed using receiver-operator characteristic curves to derive optimal thresholds for combined patient data (pooled analysis) and individual patients (patient-level analysis) based on time from stroke onset-to-CTP and CTP-to-reperfusion. One-way ANOVA and locally weighted scatterplot smoothing regression was used to test whether the derived optimal CTP thresholds were different by time. One hundred and thirty-two patients were included. Tmax thresholds of >16.2 and >15.8 s and absolute cerebral blood flow thresholds of <8.9 and <7.4 mL·min(-1)·100 g(-1) were associated with infarct if reperfused <90 min from CTP with onset <180 min. The discriminative ability of cerebral blood volume was modest. No statistically significant relationship was noted between stroke onset-to-CTP time and the optimal CTP thresholds for all parameters based on discrete or continuous time analysis (P>0.05). A statistically significant relationship existed between CTP-to-reperfusion time and the optimal thresholds for cerebral blood flow (P<0.001; r=0.59 and 0.77 for gray and white matter, respectively) and Tmax (P<0.001; r=-0.68 and -0.60 for gray and white matter, respectively) parameters. Optimal CTP thresholds associated with follow-up infarction depend on time from imaging to reperfusion. © 2015 American Heart Association, Inc.

  20. Multiple runoff processes and multiple thresholds control agricultural runoff generation

    NASA Astrophysics Data System (ADS)

    Saffarpour, Shabnam; Western, Andrew W.; Adams, Russell; McDonnell, Jeffrey J.

    2016-11-01

    Thresholds and hydrologic connectivity associated with runoff processes are a critical concept for understanding catchment hydrologic response at the event timescale. To date, most attention has focused on single runoff response types, and the role of multiple thresholds and flow path connectivities has not been made explicit. Here we first summarise existing knowledge on the interplay between thresholds, connectivity and runoff processes at the hillslope-small catchment scale into a single figure and use it in examining how runoff response and the catchment threshold response to rainfall affect a suite of runoff generation mechanisms in a small agricultural catchment. A 1.37 ha catchment in the Lang Lang River catchment, Victoria, Australia, was instrumented and hourly data of rainfall, runoff, shallow groundwater level and isotope water samples were collected. The rainfall, runoff and antecedent soil moisture data together with water levels at several shallow piezometers are used to identify runoff processes in the study site. We use isotope and major ion results to further support the findings of the hydrometric data. We analyse 60 rainfall events that produced 38 runoff events over two runoff seasons. Our results show that the catchment hydrologic response was typically controlled by the Antecedent Soil Moisture Index and rainfall characteristics. There was a strong seasonal effect in the antecedent moisture conditions that led to marked seasonal-scale changes in runoff response. Analysis of shallow well data revealed that streamflows early in the runoff season were dominated primarily by saturation excess overland flow from the riparian area. As the runoff season progressed, the catchment soil water storage increased and the hillslopes connected to the riparian area. The hillslopes transferred a significant amount of water to the riparian zone during and following events. Then, during a particularly wet period, this connectivity to the riparian zone, and ultimately to the stream, persisted between events for a period of 1 month. These findings are supported by isotope results which showed the dominance of pre-event water, together with significant contributions of event water early (rising limb and peak) in the event hydrograph. Based on a combination of various hydrometric analyses and some isotope and major ion data, we conclude that event runoff at this site is typically a combination of subsurface event flow and saturation excess overland flow. However, during high intensity rainfall events, flashy catchment flow was observed even though the soil moisture threshold for activation of subsurface flow was not exceeded. We hypothesise that this was due to the activation of infiltration excess overland flow and/or fast lateral flow through preferential pathways on the hillslope and saturation overland flow from the riparian zone.

  1. Characterization of turbulent coherent structures in square duct flow

    NASA Astrophysics Data System (ADS)

    Atzori, Marco; Vinuesa, Ricardo; Lozano-Durán, Adrián; Schlatter, Philipp

    2018-04-01

    This work is aimed at a first characterization of coherent structures in turbulent square duct flows. Coherent structures are defined as connected components in the domain identified as places where a quantity of interest (such as Reynolds stress or vorticity) is larger than a prescribed non-uniform threshold. Firstly, we qualitatively discuss how a percolation analysis can be used to assess the effectiveness of the threshold function, and how it can be affected by statistical uncertainty. Secondly, various physical quantities that are expected to play an important role in the dynamics of the secondary flow of Prandtl’s second kind are studied. Furthermore, a characterization of intense Reynolds-stress events in square duct flow, together with a comparison of their shape for analogous events in channel flow at the same Reynolds number, is presented.

  2. Effects of Weight Loss on Acoustic Parameters After Bariatric Surgery.

    PubMed

    de Souza, Lourdes Bernadete Rocha; Dos Santos, Marquiony Marques; Pernambuco, Leandro Araújo; de Almeida Godoy, Cynthia Meira; da Silva Lima, Deysianne Meire

    2018-05-01

    Patients with morbid obesity may present vocal alterations, since large accumulation of fat in the vocal tract may interfere with voice production of these individuals. Verify the neck circumference and the acoustic parameters of voice in obese women, before and after the bariatric surgery, and compare the results with a control group, with normal weight. Observational, longitudinal, descriptive study with patients referred to the SCODE (Obesity Surgery and Related Disorders Center) in a university hospital. The sample consisted of 25 morbidly obese women, age range 28-43 years and 23 non-obese women, aged 21-41 years control group. To measure the neck circumference, a tape measure was used and all participants were seated upright with the head positioned in the Frankfort horizontal plane. The fundamental frequency was calculated through the sustained emission of vowel [a] at usual intensity and pitch, to measure the fundamental frequency of the voice, that is, how much the vocal fold vibrates per second. After the recording, participants were prompted to produce vowels [a], [i], and [u] sustained at usual intensity and pitch, and a stopwatch was used to measure the maximum phonation time, to verify the balance between myoelastic and dynamic forces of the larynx. After 8 months post-surgery, the patients were recruited to be re-evaluated using the same pre-surgical data collection procedures. There was an increase in the mean value of f0. The maximum phonation time of all vowels increased after surgery. Obese individuals with post-surgery weight loss may present neck circumference, fundamental frequency, and maximum phonation time values closer to the mean values of normal weight individuals. In this study, weight loss was sufficient to adjust the acoustic parameter measurements.

  3. Influence of glottal closure configuration on vocal efficacy in young normal-speaking women.

    PubMed

    Schneider, Berit; Bigenzahn, Wolfgang

    2003-12-01

    Posterior closure insufficiency of the glottis is often mentioned in connection with permanent voice disorders. Recently published studies have revealed that an incomplete closure of the glottis can be found also in normal-speaking voices, especially in women. However, the effect of glottal closure configuration on vocal efficacy is not sufficiently clarified. The purpose of this study was to determine the effect of glottal closure configuration on singing and speaking voice characteristics. Overall, 520 young female normal-speaking subjects were examined by videostroboscopy for different phonation conditions in the combination of soft, loud, low, and/or high phonation and by voice range profile measurements. According to the videostroboscopic analysis, the subjects were subdivided into four groups: complete closure of the vocal folds already in soft phonation (group 1), closure of the vocal fold with increasing intensity (group 2), persistent closure insufficiencies despite increasing intensity (group 3), and hourglass-shaped closure in subjects with vocal nodules (group 4). Subjects in which the glottal closure could not be evaluated sufficiently were subclassified into group 5 (missing values). Selected criteria of the singing and speaking voice were evaluated and statistically processed according to the mentioned subclassification. Group 1 reached significantly the highest sound pressure levels (SPLmax) for the singing voice as well as for the shouting voice. Group 3 showed a limited capacity to increase the intensity of the singing and speaking voice. The results gathered in this study objectify the relationship of insufficient glottal closure and reduced vocal capabilities. As long as no conclusive data on long-term consequences of insufficient glottal closure are available, a prophylactic improvement of the laryngeal situation especially in female professional voice users by voice therapy should be recommended.

  4. Pediatric normative data for the KayPENTAX phonatory aerodynamic system model 6600.

    PubMed

    Weinrich, Barbara; Brehm, Susan Baker; Knudsen, Courtney; McBride, Stephanie; Hughes, Michael

    2013-01-01

    The objectives of this study were to (1) establish a preliminary pediatric normative database for the KayPENTAX Phonatory Aerodynamic System (PAS) Model 6600 (KayPENTAX Corp, Montvale, NJ) and (2) identify whether the data obtained were age- and/or gender-dependent. Prospective data collection across groups. A sample of 60 children (30 females and 30 males) with normal voices was divided into three age groups (6.0-9.11, 10.0-13.11, 14.0-17.11 years) with equal distribution of males and females within each group. Five PAS protocols (vital capacity, maximum sustained phonation, comfortable sustained phonation, variation in sound pressure level, voicing efficiency) were used to collect 45 phonatory aerodynamic measures. Measurements for the 45 PAS parameters examined revealed 13 parameters to have a difference that was statistically significant by age and/or gender. There was a significant age×gender interaction for mean pitch in the four protocols that reported this measure. Males in the oldest group had significantly lower mean pitch values than the middle and young groups. Statistically significant main effect differences were noted for seven parameters across three age groups (expiratory volume, expiratory airflow duration, phonation time, pitch range (in 2 protocols), aerodynamic resistance, acoustic ohms). Significant main effect differences for genders (males > females) were found for expiratory volume and peak expiratory airflow. The age- and gender-related differences found for some parameters within each of the five protocols are important for the interpretation of data obtained from PAS. These results could be explained by developmental changes that occur in the male and female respiratory and laryngeal systems. Copyright © 2013 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  5. Frequency Characteristics in Animal Species Typically Used in Laryngeal Research: An Exploratory Investigation.

    PubMed

    Riley, Jennifer L; Riley, William D; Carroll, Linda M

    2016-11-01

    Laryngeal research is typically conducted on animal species that have similar features to the human larynx, yet little is known of the frequency characteristics of those animals. This study examines frequency characteristics of dog, cat, pig, and sheep across emotional communication events. Prospective study. Acoustic data were gathered in domestic environment, with fundamental frequency (f o ) computation of vocalization during happy, distress, and food request activities. Dogs demonstrated reduced f o range and reduced vocalization as a factor of age (18 semitones for adult male dog, three semitones for aged male dog). When two barks were present, the second bark was typically shorter in length and had a higher f o . Male cat was observed to be more talkative and exhibited a much higher purr f o than his female housemate. Cat purr was varied by sex between the typical 25 Hz and a significantly higher f o , consistent with literature on use of cry-purr by some cats. Lambs exhibited phonation breaks, and an overall frequency range of 28 semitones in lambs compared with 49 semitones for mature sheep. Piglets exhibited f o range of 44 semitones with higher f o with distress and lowest f o for grunting. Aged animals followed similar phonatory patterns of humans, with change of f o for communication need. The male cat was found to purr differently from female cats. Pigs and cats may have nonlaryngeal source signal coupling. Animal phonation changes with emotion. Observed f o patterns may improve interpretation of phonation among laboratory animals in laryngeal research. Copyright © 2016 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  6. Acoustic Studies of the Effects of Environmental Stresses on Marine Mammals in Large Ocean Basins

    NASA Astrophysics Data System (ADS)

    Sidorovskaia, N.; Ma, B.; Ackleh, A. S.; Tiemann, C.; Ioup, G. E.; Ioup, J. W.

    2014-12-01

    Effects of environmental stresses on deep-diving marine mammal populations have not been studied systematically. Long-term regional passive acoustic monitoring of phonating marine mammals opens opportunities for such studies. This paper presents a unique multi-year study conducted by the Littoral Acoustic Demonstration Center (LADC) in the Northern Gulf of Mexico to understand short-term and long-term effects of anthropogenic stresses on resident populations of endangered sperm and elusive beaked whales. Both species spend many hours each day in deep dives which last about one hour each, so any visual observations for population estimates and behavioral responses are very limited. However, much more cost-efficient acoustic recordings of the phonations during dives on bottom-mounted hydrophones are not skewed by weather conditions or daylight requirements. Broadband passive acoustic data were collected by LADC in 2007 and 2010 at three ranges, 15, 40, and 80 km away from the 2010 Deep Water Horizon oil spill site. Pre-spill and post-spill data processing and comparison allow observing responses of both species to local short-term environmental condition changes and long-term responses to the spill. The short-term effects are studied by correlating daily activity cycles with anthropogenic noise curve daily and weekly cycles at different sites. The strong correlation between the decrease in overall daily activity and the increase in anthropogenic noise level associated with seismic exploration signals can be seen. After streaming raw acoustic data through detection algorithms and detailed assessment of false detection rates, the temporal densities of acoustic phonations are passed into statistical algorithms for resident population estimations. The statistically significant results have shown different regional abundance trends, associated with long-term responses to environmental stresses, for these two species.

  7. Voice amplification as a means of reducing vocal load for elementary music teachers.

    PubMed

    Morrow, Sharon L; Connor, Nadine P

    2011-07-01

    Music teachers are over four times more likely than classroom teachers to develop voice disorders and greater than eight times more likely to have voice-related problems than the general public. Research has shown that individual voice-use parameters of phonation time, fundamental frequency and vocal intensity, as well as vocal load as calculated by cycle dose and distance dose are significantly higher for music teachers than their classroom teacher counterparts. Finding effective and inexpensive prophylactic measures to decrease vocal load for music teachers is an important aspect for voice preservation for this group of professional voice users. The purpose of this study was to determine the effects of voice amplification on vocal intensity and vocal load in the workplace as measured using a KayPENTAX Ambulatory Phonation Monitor (APM) (KayPENTAX, Lincoln Park, NJ). Seven music teachers were monitored for 1 workweek using an APM to determine average vocal intensity (dB sound pressure level [SPL]) and vocal load as calculated by cycle dose and distance dose. Participants were monitored a second week while using a voice amplification unit (Asyst ChatterVox; Asyst Communications Company, Inc., Indian Creek, IL). Significant decreases in mean vocal intensity of 7.00-dB SPL (P<0.001) were found using amplification, along with significant decreases (P=0.001) in cycle dose and distance dose. In addition, mean phonation time was found to decrease using amplification (P=0.023). These data suggest that voice amplification may be an effective intervention to decrease the potentially damaging vocal loads experienced by elementary music teachers in the classroom. Copyright © 2011 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  8. Systematic studies of modified vocalization: the effect of speech rate on speech production measures during metronome-paced speech in persons who stutter.

    PubMed

    Davidow, Jason H

    2014-01-01

    Metronome-paced speech results in the elimination, or substantial reduction, of stuttering moments. The cause of fluency during this fluency-inducing condition is unknown. Several investigations have reported changes in speech pattern characteristics from a control condition to a metronome-paced speech condition, but failure to control speech rate between conditions limits our ability to determine if the changes were necessary for fluency. This study examined the effect of speech rate on several speech production variables during one-syllable-per-beat metronomic speech in order to determine changes that may be important for fluency during this fluency-inducing condition. Thirteen persons who stutter (PWS), aged 18-62 years, completed a series of speaking tasks. Several speech production variables were compared between conditions produced at different metronome beat rates, and between a control condition and a metronome-paced speech condition produced at a rate equal to the control condition. Vowel duration, voice onset time, pressure rise time and phonated intervals were significantly impacted by metronome beat rate. Voice onset time and the percentage of short (30-100 ms) phonated intervals significantly decreased from the control condition to the equivalent rate metronome-paced speech condition. A reduction in the percentage of short phonated intervals may be important for fluency during syllable-based metronome-paced speech for PWS. Future studies should continue examining the necessity of this reduction. In addition, speech rate must be controlled in future fluency-inducing condition studies, including neuroimaging investigations, in order for this research to make a substantial contribution to finding the fluency-inducing mechanism of fluency-inducing conditions. © 2013 Royal College of Speech and Language Therapists.

  9. The Distribution and Severity of Tremor in Speech Structures of Persons with Vocal Tremor.

    PubMed

    Hemmerich, Abby L; Finnegan, Eileen M; Hoffman, Henry T

    2017-05-01

    Vocal tremor may be associated with cyclic oscillations in the pulmonary, laryngeal, velopharyngeal, or oral regions. This study aimed to correlate the overall severity of vocal tremor with the distribution and severity of tremor in structures involved. Endoscopic and clinical examinations were completed on 20 adults with vocal tremor and two age-matched controls during sustained phonation. Two judges rated the severity of vocal tremor and the severity of tremor affecting each of 13 structures. Participants with mild vocal tremor typically presented with tremor in three laryngeal structures, moderate vocal tremor in five structures (laryngeal and another region), and severe vocal tremor in eight structures affecting all regions. The severity of tremor was lowest (mean = 1.2 out of 3) in persons with mild vocal tremor and greater in persons with moderate (mean = 1.5) and severe vocal tremor (mean = 1.4). Laryngeal structures were most frequently (95%) and severely (1.7 out of 3) affected, followed by velopharynx (40% occurrence, 1.3 severity), pulmonary (40% occurrence, 1.1 severity), and oral (40% occurrence, 1.0 severity) regions. Regression analyses indicated tremor severity of the supraglottic structures, and vertical laryngeal movement contributed most to vocal tremor severity during sustained phonation (r = 0.77, F = 16.17, P < 0.0001). A strong positive correlation (r = 0.72) was found between the Tremor Index and the severity of the vocal tremor during sustained phonation. It is useful to obtain a wide endoscopic view of the larynx to visualize tremor, which is rarely isolated to the true vocal folds alone. Published by Elsevier Inc.

  10. Systematic Studies of Modified Vocalization: The Effect of Speech Rate on Speech Production Measures During Metronome-Paced Speech in Persons who Stutter

    PubMed Central

    Davidow, Jason H.

    2013-01-01

    Background Metronome-paced speech results in the elimination, or substantial reduction, of stuttering moments. The cause of fluency during this fluency-inducing condition is unknown. Several investigations have reported changes in speech pattern characteristics from a control condition to a metronome-paced speech condition, but failure to control speech rate between conditions limits our ability to determine if the changes were necessary for fluency. Aims This study examined the effect of speech rate on several speech production variables during one-syllable-per-beat metronomic speech, in order to determine changes that may be important for fluency during this fluency-inducing condition. Methods and Procedures Thirteen persons who stutter (PWS), aged 18–62 years, completed a series of speaking tasks. Several speech production variables were compared between conditions produced at different metronome beat rates, and between a control condition and a metronome-paced speech condition produced at a rate equal to the control condition. Outcomes & Results Vowel duration, voice onset time, pressure rise time, and phonated intervals were significantly impacted by metronome beat rate. Voice onset time and the percentage of short (30–100 ms) phonated intervals significantly decreased from the control condition to the equivalent rate metronome-paced speech condition. Conclusions & Implications A reduction in the percentage of short phonated intervals may be important for fluency during syllable-based metronome-paced speech for PWS. Future studies should continue examining the necessity of this reduction. In addition, speech rate must be controlled in future fluency-inducing condition studies, including neuroimaging investigations, in order for this research to make a substantial contribution to finding the fluency-inducing mechanism of fluency-inducing conditions. PMID:24372888

  11. Rainfall characteristics and thresholds for periglacial debris flows in the Parlung Zangbo Basin, southeast Tibetan Plateau

    NASA Astrophysics Data System (ADS)

    Deng, Mingfeng; Chen, Ningsheng; Ding, Haitao

    2018-02-01

    The Parlung Zangbo Basin in the southeastern Tibet Plateau is affected by the summer monsoon from the Indian Ocean, which produces large rainfall gradients in the basin. Rainfall data during 2012-2015 from five new meteorological stations are used to analyse the rainfall characteristics. The daily rainfall, rainfall duration, mean rainfall intensity, and peak rainfall intensity are consistent, but sometimes contrasting. For example, these values decrease with increasing altitude, and the gradient is large downstream and small upstream, respectively. Moreover, the rainfall intensity peaks between 01:00 and 06:00 and increases during the afternoon. Based on the analysis of 14 debris flow cases in the basin, differences in the rainfall threshold differ depending on the location as sediment varieties. The sediment in the middle portions of the basin is wet and well structured; thus, long-duration, high-intensity rainfall is required to generate debris flows. Ravels in the upstream area are arid and not well structured, and short-duration rainfall is required to trigger debris flows. Between the above two locations, either long-duration, low-intensity rainfall or short-duration, high-intensity rainfall could provoke debris flows. Clearly, differences in rainfall characteristics and rainfall thresholds that are associated with the location must be considered in debris flow monitoring and warnings.

  12. Hydrodynamic Capture and Release of Passively Driven Particles by Active Particles Under Hele-Shaw Flows

    NASA Astrophysics Data System (ADS)

    Mishler, Grant; Tsang, Alan Cheng Hou; Pak, On Shun

    2018-03-01

    The transport of active and passive particles plays central roles in diverse biological phenomena and engineering applications. In this paper, we present a theoretical investigation of a system consisting of an active particle and a passive particle in a confined micro-fluidic flow. The introduction of an external flow is found to induce the capture of the passive particle by the active particle via long-range hydrodynamic interactions among the particles. This hydrodynamic capture mechanism relies on an attracting stable equilibrium configuration formed by the particles, which occurs when the external flow intensity exceeds a certain threshold. We evaluate this threshold by studying the stability of the equilibrium configurations analytically and numerically. Furthermore, we study the dynamics of typical capture and non-capture events and characterize the basins of attraction of the equilibrium configurations. Our findings reveal a critical dependence of the hydrodynamic capture mechanism on the external flow intensity. Through adjusting the external flow intensity across the stability threshold, we demonstrate that the active particle can capture and release the passive particle in a controllable manner. Such a capture-and-release mechanism is desirable for biomedical applications such as the capture and release of therapeutic payloads by synthetic micro-swimmers in targeted drug delivery.

  13. External Validation of the Acoustic Voice Quality Index Version 03.01 With Extended Representativity.

    PubMed

    Barsties, Ben; Maryn, Youri

    2016-07-01

    The Acoustic Voice Quality Index (AVQI) is an objective method to quantify the severity of overall voice quality in concatenated continuous speech and sustained phonation segments. Recently, AVQI was successfully modified to be more representative and ecologically valid because the internal consistency of AVQI was balanced out through equal proportion of the 2 speech types. The present investigation aims to explore its external validation in a large data set. An expert panel of 12 speech-language therapists rated the voice quality of 1058 concatenated voice samples varying from normophonia to severe dysphonia. The Spearman rank-order correlation coefficients (r) were used to measure concurrent validity. The AVQI's diagnostic accuracy was evaluated with several estimates of its receiver operating characteristics (ROC). Finally, 8 of the 12 experts were chosen because of reliability criteria. A strong correlation was identified between AVQI and auditoryperceptual rating (r = 0.815, P = .000). It indicated that 66.4% of the auditory-perceptual rating's variation was explained by AVQI. Additionally, the ROC results showed again the best diagnostic outcome at a threshold of AVQI = 2.43. This study highlights external validation and diagnostic precision of the AVQI version 03.01 as a robust and ecologically valid measurement to objectify voice quality. © The Author(s) 2016.

  14. Influence and interactions of laryngeal adductors and cricothyroid muscles on fundamental frequency and glottal posture control

    PubMed Central

    Chhetri, Dinesh K.; Neubauer, Juergen; Sofer, Elazar; Berry, David A.

    2014-01-01

    The interactions of the intrinsic laryngeal muscles (ILMs) in controlling fundamental frequency (F0) and glottal posture remain unclear. In an in vivo canine model, three sets of intrinsic laryngeal muscles—the thyroarytenoid (TA), cricothyroid (CT), and lateral cricoarytenoid plus interarytenoid (LCA/IA) muscle complex—were independently and accurately stimulated in a graded manner using distal laryngeal nerve stimulation. Graded neuromuscular stimulation was used to independently activate these paired intrinsic laryngeal muscles over a range from threshold to maximal activation, to produce 320 distinct laryngeal phonatory postures. At phonation onset these activation conditions were evaluated in terms of their vocal fold strain, glottal width at the vocal processes, fundamental frequency (F0), subglottic pressure, and airflow. F0 ranged from 69 to 772 Hz and clustered into chest-like and falsetto-like groups. CT activation was always required to raise F0, but could also lower F0 at low TA and LCA/IA activation levels. Increasing TA activation first increased then decreased F0 in all CT and LCA/IA activation conditions. Increasing TA activation also facilitated production of high F0 at a lower onset pressure. Independent control of membranous (TA) and cartilaginous (LCA/IA) glottal closure enabled multiple pathways for F0 control via changes in glottal posture. PMID:25235003

  15. Bi-stable vocal fold adduction: a mechanism of modal-falsetto register shifts and mixed registration.

    PubMed

    Titze, Ingo R

    2014-04-01

    The origin of vocal registers has generally been attributed to differential activation of cricothyroid and thyroarytenoid muscles in the larynx. Register shifts, however, have also been shown to be affected by glottal pressures exerted on vocal fold surfaces, which can change with loudness, pitch, and vowel. Here it is shown computationally and with empirical data that intraglottal pressures can change abruptly when glottal adductory geometry is changed relatively smoothly from convergent to divergent. An intermediate shape between large convergence and large divergence, namely, a nearly rectangular glottal shape with almost parallel vocal fold surfaces, is associated with mixed registration. It can be less stable than either of the highly angular shapes unless transglottal pressure is reduced and upper stiffness of vocal fold tissues is balanced with lower stiffness. This intermediate state of adduction is desirable because it leads to a low phonation threshold pressure with moderate vocal fold collision. Achieving mixed registration consistently across wide ranges of F0, lung pressure, and vocal tract shapes appears to be a balancing act of coordinating laryngeal muscle activation with vocal tract pressures. Surprisingly, a large transglottal pressure is not facilitative in this process, exacerbating the bi-stable condition and the associated register contrast.

  16. Nebulized isotonic saline versus water following a laryngeal desiccation challenge in classically trained sopranos.

    PubMed

    Tanner, Kristine; Roy, Nelson; Merrill, Ray M; Muntz, Faye; Houtz, Daniel R; Sauder, Cara; Elstad, Mark; Wright-Costa, Julie

    2010-12-01

    To examine the effects of nebulized isotonic saline (IS) versus sterile water (SW) on self-perceived phonatory effort (PPE) and phonation threshold pressure (PTP) following a surface laryngeal dehydration challenge in classically trained sopranos. In a double-blind, within-subject crossover design, 34 sopranos breathed dry air (relative humidity < 1%) transorally for 15 min and then nebulized 3 mL of IS or SW, or experienced a no-treatment control condition over 3 consecutive weeks. PPE and PTP were measured every 15 min from baseline through 2 hr postdesiccation. PPE increased significantly following the laryngeal desiccation challenge in all 3 treatment conditions (p < .01). After nebulization, PPE returned to baseline for the IS condition only. For the SW and control conditions, PPE remained above baseline during the 2 hr after desiccation. No statistically significant changes in PTP following laryngeal desiccation were observed, although values for the IS condition remained below baseline for nearly 2 hr after nebulization. PPE and PTP were not significantly correlated. Following a laryngeal surface dehydration challenge, classically trained sopranos reported increased vocal effort that persisted for at least 2 hr. Compared with SW, nebulized IS showed promise as an effective way to remediate the adverse, self-perceived effects of laryngeal desiccation.

  17. Bi-stable vocal fold adduction: A mechanism of modal-falsetto register shifts and mixed registration

    PubMed Central

    Titze, Ingo R.

    2014-01-01

    The origin of vocal registers has generally been attributed to differential activation of cricothyroid and thyroarytenoid muscles in the larynx. Register shifts, however, have also been shown to be affected by glottal pressures exerted on vocal fold surfaces, which can change with loudness, pitch, and vowel. Here it is shown computationally and with empirical data that intraglottal pressures can change abruptly when glottal adductory geometry is changed relatively smoothly from convergent to divergent. An intermediate shape between large convergence and large divergence, namely, a nearly rectangular glottal shape with almost parallel vocal fold surfaces, is associated with mixed registration. It can be less stable than either of the highly angular shapes unless transglottal pressure is reduced and upper stiffness of vocal fold tissues is balanced with lower stiffness. This intermediate state of adduction is desirable because it leads to a low phonation threshold pressure with moderate vocal fold collision. Achieving mixed registration consistently across wide ranges of F0, lung pressure, and vocal tract shapes appears to be a balancing act of coordinating laryngeal muscle activation with vocal tract pressures. Surprisingly, a large transglottal pressure is not facilitative in this process, exacerbating the bi-stable condition and the associated register contrast. PMID:25235006

  18. Erosive Burning Study Utilizing Ultrasonic Measurement Techniques

    NASA Technical Reports Server (NTRS)

    Furfaro, James A.

    2003-01-01

    A 6-segment subscale motor was developed to generate a range of internal environments from which multiple propellants could be characterized for erosive burning. The motor test bed was designed to provide a high Mach number, high mass flux environment. Propellant regression rates were monitored for each segment utilizing ultrasonic measurement techniques. These data were obtained for three propellants RSRM, ETM- 03, and Castor@ IVA, which span two propellant types, PBAN (polybutadiene acrylonitrile) and HTPB (hydroxyl terminated polybutadiene). The characterization of these propellants indicates a remarkably similar erosive burning response to the induced flow environment. Propellant burnrates for each type had a conventional response with respect to pressure up to a bulk flow velocity threshold. Each propellant, however, had a unique threshold at which it would experience an increase in observed propellant burn rate. Above the observed threshold each propellant again demonstrated a similar enhanced burn rate response corresponding to the local flow environment.

  19. Setting objective thresholds for rare event detection in flow cytometry

    PubMed Central

    Richards, Adam J.; Staats, Janet; Enzor, Jennifer; McKinnon, Katherine; Frelinger, Jacob; Denny, Thomas N.; Weinhold, Kent J.; Chan, Cliburn

    2014-01-01

    The accurate identification of rare antigen-specific cytokine positive cells from peripheral blood mononuclear cells (PBMC) after antigenic stimulation in an intracellular staining (ICS) flow cytometry assay is challenging, as cytokine positive events may be fairly diffusely distributed and lack an obvious separation from the negative population. Traditionally, the approach by flow operators has been to manually set a positivity threshold to partition events into cytokine-positive and cytokine-negative. This approach suffers from subjectivity and inconsistency across different flow operators. The use of statistical clustering methods does not remove the need to find an objective threshold between between positive and negative events since consistent identification of rare event subsets is highly challenging for automated algorithms, especially when there is distributional overlap between the positive and negative events (“smear”). We present a new approach, based on the Fβ measure, that is similar to manual thresholding in providing a hard cutoff, but has the advantage of being determined objectively. The performance of this algorithm is compared with results obtained by expert visual gating. Several ICS data sets from the External Quality Assurance Program Oversight Laboratory (EQAPOL) proficiency program were used to make the comparisons. We first show that visually determined thresholds are difficult to reproduce and pose a problem when comparing results across operators or laboratories, as well as problems that occur with the use of commonly employed clustering algorithms. In contrast, a single parameterization for the Fβ method performs consistently across different centers, samples, and instruments because it optimizes the precision/recall tradeoff by using both negative and positive controls. PMID:24727143

  20. Is insufficient pulmonary air support the cause of dysphonia in chronic obstructive pulmonary disease?

    PubMed

    Hassan, Megahed M; Hussein, Mona T; Emam, Ahmed Mamdouh; Rashad, Usama M; Rezk, Ibrahim; Awad, Al Hussein

    2018-08-01

    Optimal pulmonary air support is essential pre-requisite for efficient phonation. The objective is to correlate pulmonary and vocal functions in chronic obstructive pulmonary disease (COPD) to find out whether the reduced pulmonary function per se could induce dysphonia. In this prospective case-control study, sixty subjects with stable COPD underwent evaluation of pulmonary and vocal functions. The pulmonary functions measured include {Forced vital capacity (FVC), forced expiratory volume in the first second (FEV1), FEV1/FVC ratio, peak expiratory flow (PEF), maximum mid-expiratory flow (MMEF)}. The vocal functions were {jitter, shimmer, noise-to-harmonic ratio, pitch perturbation quotient, amplitude perturbation quotient, maximum phonation time (MPT), sound pressure level, phonatory efficiency, resistance and power. A control group (n=35) underwent the same measurements. These functions were compared between subjects and controls. Also, correlation of the vocal and pulmonary functions was conducted. Thirty five (58.3%) of COPD subjects have dysphonia. The pulmonary functions were lower in all COPD group than in the control group (P<0.001 for all parameters). Also, the FVC, FEV1, PEF and MMEF % of predicted values were significantly lower in subjects with dysphonia (n=35) than those without dysphonia (n=25) with P values 0.0018, <0.001, 0.0011 and 0.0026 respectively. In addition, the MPT in all subjects showed positive correlations to the 5 pulmonary functions (P=0.004 for FEV1/FVC ratio and P<0.001 for the rest). Also, the phonatory efficiency showed significant positive correlations with the pulmonary functions FVC, FEV1, PEF and MMEF (P=0.001, 0.001, 0.002 and 0.001 respectively). Unlike efficiency, the phonatory resistance revealed significant negative correlations with these pulmonary functions in the same order (P=0.001, 0.003, 0.002, 0.001 respectively). Dysphonia is a common comorbidity with COPD which attributed to multifactorial etiologies. The lower the pulmonary function in COPD patients is the more likely to have dysphonia. Decreased pulmonary function was associated with reduced MPT and phonatory efficiency but with increased phonatory resistance. The reduced pulmonary functions in COPD can be the underlying cause of the altered vocal function and dysphonia. Great part of this dysphonia is functional, and hence, can be corrected by voice therapy in compensated subjects. Further researches are needed to evaluate the efficacy of voice therapy in these patients. Copyright © 2017 Elsevier B.V. All rights reserved.

  1. A Model for Evaluating Tactually Assistive Devices.

    ERIC Educational Resources Information Center

    Terrio, Lee; Haas, William

    1986-01-01

    Audiometric instruments and techniques adopted to measure tactual cueing characteristics of the Radioear B70A and the Siemens Fonator electromechanical vibrators were used by young adults. The Siemens Phonator demonstrated a wider suprathreshold operating range than did the Radioear B70A. (Author/CL)

  2. High-speed imaging of vocal fold vibrations and larynx movements within vocalizations of different vowels.

    PubMed

    Maurer, D; Hess, M; Gross, M

    1996-12-01

    Theoretic investigations of the "source-filter" model have indicated a pronounced acoustic interaction of glottal source and vocal tract. Empirical investigations of formant pattern variations apart from changes in vowel identity have demonstrated a direct relationship between the fundamental frequency and the patterns. As a consequence of both findings, independence of phonation and articulation may be limited in the speech process. Within the present study, possible interdependence of phonation and phoneme was investigated: vocal fold vibrations and larynx position for vocalizations of different vowels in a healthy man and woman were examined by high-speed light-intensified digital imaging. We found 1) different movements of the vocal folds for vocalizations of different vowel identities within one speaker and at similar fundamental frequency, and 2) constant larynx position within vocalization of one vowel identity, but different positions for vocalizations of different vowel identities. A possible relationship between the vocal fold vibrations and the phoneme is discussed.

  3. Neuromuscular control of fundamental frequency and glottal posture at phonation onset

    PubMed Central

    Chhetri, Dinesh K.; Neubauer, Juergen; Berry, David A.

    2012-01-01

    The laryngeal neuromuscular mechanisms for modulating glottal posture and fundamental frequency are of interest in understanding normal laryngeal physiology and treating vocal pathology. The intrinsic laryngeal muscles in an in vivo canine model were electrically activated in a graded fashion to investigate their effects on onset frequency, phonation onset pressure, vocal fold strain, and glottal distance at the vocal processes. Muscle activation plots for these laryngeal parameters were evaluated for the interaction of following pairs of muscle activation conditions: (1) cricothyroid (CT) versus all laryngeal adductors (TA/LCA/IA), (2) CT versus LCA/IA, (3) CT versus thyroarytenoid (TA) and, (4) TA versus LCA/IA (LCA: lateral cricoarytenoid muscle, IA: interarytenoid). Increases in onset frequency and strain were primarily affected by CT activation. Onset pressure correlated with activation of all adductors in activation condition 1, but primarily with CT activation in conditions 2 and 3. TA and CT were antagonistic for strain. LCA/IA activation primarily closed the cartilaginous glottis while TA activation closed the mid-membranous glottis. PMID:22352513

  4. Propagation modeling for sperm whale acoustic clicks in the northern Gulf of Mexico

    NASA Astrophysics Data System (ADS)

    Sidorovskaia, Natalia A.; Udovydchenkov, Ilya A.; Rypina, Irina I.; Ioup, George E.; Ioup, Juliette W.; Caruthers, Jerald W.; Newcomb, Joal; Fisher, Robert

    2004-05-01

    Simulations of acoustic broadband (500-6000 Hz) pulse propagation in the northern Gulf of Mexico, based on environmental data collected as a part of the Littoral Acoustic Demonstration Center (LADC) experiments in the summers of 2001 and 2002, are presented. The results of the modeling support the hypothesis that consistent spectrogram interference patterns observed in the LADC marine mammal phonation data cannot be explained by the propagation effects for temporal analysis windows corresponding to the duration of an animal click, and may be due to a uniqueness of an individual animal phonation apparatus. The utilization of simulation data for the development of an animal tracking algorithm based on the acoustic recordings of a single bottom-moored hydrophone is discussed. The identification of the bottom and surface reflected clicks from the same animal is attempted. The critical ranges for listening to a deep-water forging animal by a surface receiving system are estimated. [Research supported by ONR.

  5. Fo-perturbation and Fo/loudness dynamics in voices of normal children, with and without education in singing.

    PubMed

    Dejonckere, P H; Wieneke, G H; Bloemenkamp, D; Lebacq, J

    1996-04-01

    Sustained phonations were compared in two groups of children (aged 7-12), one with special artistic voice education and one from a normal school, without voice complaints or problems. The hypothesis of specific (better) biomechanical vocal fold properties in the first group is confronted with the hypothesis of differences solely related to training of voice control. In both groups, Fo-aperiodicity was measured in a sustained phonation at 3 different SPL levels. As a general rule, aperiodicity clearly decreases when the voice becomes louder. Aperiodicity is highly significantly lower, at all SPL-levels, in children with trained singing voices: this implies better mechanical properties of the vocal oscillator. The Fo/SPL relation on a sustained /a:/ does not differ in trained and untrained children's voices: out of singing context, trained children do not spontaneously control the Fo/SPL dynamics differently from untrained children. The higher regularity of vocal fold pulses is not related to the duration of training.

  6. In vivo cross-sectional imaging of the phonating larynx using long-range Doppler optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Coughlan, Carolyn A.; Chou, Li-Dek; Jing, Joseph C.; Chen, Jason J.; Rangarajan, Swathi; Chang, Theodore H.; Sharma, Giriraj K.; Cho, Kyoungrai; Lee, Donghoon; Goddard, Julie A.; Chen, Zhongping; Wong, Brian J. F.

    2016-03-01

    Diagnosis and treatment of vocal fold lesions has been a long-evolving science for the otolaryngologist. Contemporary practice requires biopsy of a glottal lesion in the operating room under general anesthesia for diagnosis. Current in-office technology is limited to visualizing the surface of the vocal folds with fiber-optic or rigid endoscopy and using stroboscopic or high-speed video to infer information about submucosal processes. Previous efforts using optical coherence tomography (OCT) have been limited by small working distances and imaging ranges. Here we report the first full field, high-speed, and long-range OCT images of awake patients’ vocal folds as well as cross-sectional video and Doppler analysis of their vocal fold motions during phonation. These vertical-cavity surface-emitting laser source (VCSEL) OCT images offer depth resolved, high-resolution, high-speed, and panoramic images of both the true and false vocal folds. This technology has the potential to revolutionize in-office imaging of the larynx.

  7. Price of anarchy is maximized at the percolation threshold.

    PubMed

    Skinner, Brian

    2015-05-01

    When many independent users try to route traffic through a network, the flow can easily become suboptimal as a consequence of congestion of the most efficient paths. The degree of this suboptimality is quantified by the so-called price of anarchy (POA), but so far there are no general rules for when to expect a large POA in a random network. Here I address this question by introducing a simple model of flow through a network with randomly placed congestible and incongestible links. I show that the POA is maximized precisely when the fraction of congestible links matches the percolation threshold of the lattice. Both the POA and the total cost demonstrate critical scaling near the percolation threshold.

  8. Passively actuated valve

    DOEpatents

    Modro, S. Michael; Ougouag, Abderrafi M.

    2005-09-20

    A passively actuated valve for isolating a high pressure zone from a low pressure zone and discontinuing the isolation when the pressure in the high pressure zone drops below a preset threshold. If the pressure in the high pressure zone drops below the preset threshold, the valve opens and allows flow from the high pressure zone to the low pressure zone. The valve remains open allowing pressure equalization and back-flow should a pressure inversion between the two pressure zone occur.

  9. Storm rainfall conditions for floods and debris flows from recently burned areas in southwestern Colorado and southern California

    USGS Publications Warehouse

    Cannon, S.H.; Gartner, J.E.; Wilson, R.C.; Bowers, J.C.; Laber, J.L.

    2008-01-01

    Debris flows generated during rain storms on recently burned areas have destroyed lives and property throughout the Western U.S. Field evidence indicate that unlike landslide-triggered debris flows, these events have no identifiable initiation source and can occur with little or no antecedent moisture. Using rain gage and response data from five fires in Colorado and southern California, we document the rainfall conditions that have triggered post-fire debris flows and develop empirical rainfall intensity-duration thresholds for the occurrence of debris flows and floods following wildfires in these settings. This information can provide guidance for warning systems and planning for emergency response in similar settings. Debris flows were produced from 25 recently burned basins in Colorado in response to 13 short-duration, high-intensity convective storms. Debris flows were triggered after as little as six to 10??min of storm rainfall. About 80% of the storms that generated debris flows lasted less than 3??h, with most of the rain falling in less than 1??h. The storms triggering debris flows ranged in average intensity between 1.0 and 32.0??mm/h, and had recurrence intervals of two years or less. Threshold rainfall conditions for floods and debris flows sufficiently large to pose threats to life and property from recently burned areas in south-central, and southwestern, Colorado are defined by: I = 6.5D-??0.7 and I = 9.5D-??0.7, respectively, where I = rainfall intensity (in mm/h) and D = duration (in hours). Debris flows were generated from 68 recently burned areas in southern California in response to long-duration frontal storms. The flows occurred after as little as two hours, and up to 16??h, of low-intensity (2-10??mm/h) rainfall. The storms lasted between 5.5 and 33??h, with average intensities between 1.3 and 20.4??mm/h, and had recurrence intervals of two years or less. Threshold rainfall conditions for life- and property-threatening floods and debris flows during the first winter season following fires in Ventura County, and in the San Bernardino, San Gabriel and San Jacinto Mountains of southern California are defined by I = 12.5D-0.4, and I = 7.2D-0.4, respectively. A threshold defined for flood and debris-flow conditions following a year of vegetative recovery and sediment removal for the San Bernardino, San Gabriel and San Jacinto Mountains of I = 14.0D-0.5 is approximately 25??mm/h higher than that developed for the first year following fires. The thresholds defined here are significantly lower than most identified for unburned settings, perhaps because of the difference between extremely rapid, runoff-dominated processes acting in burned areas and longer-term, infiltration-dominated processes on unburned hillslopes. Crown Copyright ?? 2007.

  10. Stochastic transitions and jamming in granular pipe flow

    NASA Astrophysics Data System (ADS)

    Brand, Samuel; Ball, Robin C.; Nicodemi, Mario

    2011-03-01

    We study a model granular suspension driven down a channel by an embedding fluid via computer simulations. We characterize the different system flow regimes and the stochastic nature of the transitions between them. For packing fractions below a threshold ϕm, granular flow is disordered and exhibits an Ostwald-de Waele-type power-law shear-stress constitutive relation. Above ϕm, two asymptotic states exist; disordered flow can persist indefinitely, yet, in a fraction of samples, the system self-organizes in an ordered form of flow where grains move in parallel ordered layers. In the latter regime, the Ostwald-de Waele relationship breaks down and a nearly solid plug appears in the center, with linear shear regions at the boundaries. Above a higher threshold ϕg, an abrupt jamming transition is observed if ordering is avoided.

  11. Illustrated Speech Anatomy.

    ERIC Educational Resources Information Center

    Shearer, William M.

    Written for students in the fields of speech correction and audiology, the text deals with the following: structures involved in respiration; the skeleton and the processes of inhalation and exhalation; phonation and pitch, the larynx, and esophageal speech; muscles involved in articulation; muscles involved in resonance; and the anatomy of the…

  12. Vocal Tremor Analysis with the Vocal Demodulator.

    ERIC Educational Resources Information Center

    Winholtz, William S.; Ramig, Lorraine Olson

    1992-01-01

    This paper describes the Vocal Demodulator as a new device for analysis of vocal tremor. The Vocal Demodulator produces amplitude-demodulated and frequency-demodulated outputs and measures the frequency and level of low-frequency tremor components in sustained phonation. The paper describes quantification of the demodulation process, validation…

  13. Audiovocal Integration in Adults Who Stutter

    ERIC Educational Resources Information Center

    Loucks, Torrey; Chon, HeeCheong; Han, Woojae

    2012-01-01

    Background: Altered auditory feedback can facilitate speech fluency in adults who stutter. However, other findings suggest that adults who stutter show anomalies in "audiovocal integration", such as longer phonation reaction times to auditory stimuli and less effective pitch tracking. Aims: To study audiovocal integration in adults who stutter…

  14. Outlier detection for particle image velocimetry data using a locally estimated noise variance

    NASA Astrophysics Data System (ADS)

    Lee, Yong; Yang, Hua; Yin, ZhouPing

    2017-03-01

    This work describes an adaptive spatial variable threshold outlier detection algorithm for raw gridded particle image velocimetry data using a locally estimated noise variance. This method is an iterative procedure, and each iteration is composed of a reference vector field reconstruction step and an outlier detection step. We construct the reference vector field using a weighted adaptive smoothing method (Garcia 2010 Comput. Stat. Data Anal. 54 1167-78), and the weights are determined in the outlier detection step using a modified outlier detector (Ma et al 2014 IEEE Trans. Image Process. 23 1706-21). A hard decision on the final weights of the iteration can produce outlier labels of the field. The technical contribution is that the spatial variable threshold motivation is embedded in the modified outlier detector with a locally estimated noise variance in an iterative framework for the first time. It turns out that a spatial variable threshold is preferable to a single spatial constant threshold in complicated flows such as vortex flows or turbulent flows. Synthetic cellular vortical flows with simulated scattered or clustered outliers are adopted to evaluate the performance of our proposed method in comparison with popular validation approaches. This method also turns out to be beneficial in a real PIV measurement of turbulent flow. The experimental results demonstrated that the proposed method yields the competitive performance in terms of outlier under-detection count and over-detection count. In addition, the outlier detection method is computational efficient and adaptive, requires no user-defined parameters, and corresponding implementations are also provided in supplementary materials.

  15. Separation of ice crystals from interstitial aerosol particles using virtual impaction at the Fifth International Ice Nucleation Workshop FIN-3

    NASA Astrophysics Data System (ADS)

    Roesch, M.; Garimella, S.; Roesch, C.; Zawadowicz, M. A.; Katich, J. M.; Froyd, K. D.; Cziczo, D. J.

    2016-12-01

    In this study, a parallel-plate ice chamber, the SPectrometer for Ice Nuclei (SPIN, DMT Inc.) was combined with a pumped counterflow virtual impactor (PCVI, BMI Inc.) to separate ice crystals from interstitial aerosol particles by their aerodynamic size. These measurements were part of the FIN-3 workshop, which took place in fall 2015 at Storm Peak Laboratory (SPL), a high altitude mountain top facility (3220 m m.s.l.) in the Rocky Mountains. The investigated particles were sampled from ambient air and were exposed to cirrus-like conditions inside SPIN (-40°C, 130% RHice). Previous SPIN experiments under these conditions showed that ice crystals were found to be in the super-micron range. Connected to the outlet of the ice chamber, the PCVI was adjusted to separate all particulates aerodynamically larger than 3.5 micrometer to the sample flow while smaller ones were rejected and removed by a pump flow. Using this technique reduces the number of interstitial aerosol particles, which could bias subsequent ice nucleating particle (INP) analysis. Downstream of the PCVI, the separated ice crystals were evaporated and the flow with the remaining INPs was split up to a particle analysis by laser mass spectrometry (PALMS) instrument a laser aerosol spectrometer (LAS, TSI Inc.) and a single particle soot photometer (SP2, DMT Inc.). Based on the sample flow and the resolution of the measured particle data, the lowest concentration threshold for the SP2 instrument was 294 INP L-1 and for the LAS instrument 60 INP L-1. Applying these thresholds as filters to the measured PALMS time series 944 valid INP spectra using the SP2 threshold and 445 valid INP spectra using the LAS threshold were identified. A sensitivity study determining the number of good INP spectra as a function of the filter threshold concentration showed a two-phase linear growth when increasing the threshold concentration showing a breakpoint around 100 INP L-1.

  16. Continuous flow nanoparticle concentration using alternating current-electroosmotic flow.

    PubMed

    Hoettges, Kai F; McDonnell, Martin B; Hughes, Michael P

    2014-02-01

    Achieving real-time detection of environmental pathogens such as viruses and bacterial spores requires detectors with both rapid action and a suitable detection threshold. However, most biosensors have detection limits of an order of magnitude or more above the potential infection threshold, limiting their usefulness. This can be improved through the use of automated sample preparation techniques such as preconcentration. In this paper, we describe the use of AC electroosmosis to concentrate nanoparticles from a continuous flow. Electrodes at an optimized angle across a flow cell, and energized by a 1 kHz signal, were used to push nanoparticles to one side of a flow cell, and to extract the resulting stream with a high particle concentration from that side of the flow cell. A simple model of the behavior of particles in the flow cell has been developed, which shows good agreement with experimental results. The method indicates potential for higher concentration factors through cascading devices. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. Nonlinear evolution of the Kelvin-Helmholtz instability in the double current sheet configuration

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mao, Aohua; Li, Jiquan, E-mail: lijq@energy.kyoto-u.ac.jp; Kishimoto, Yasuaki

    2016-03-15

    The nonlinear evolution of the Kelvin-Helmholtz (KH) instability driven by a radially antisymmetric shear flow in the double current sheet configuration is numerically investigated based on a reduced magnetohydrodynamic model. Simulations reveal different nonlinear fate of the KH instability depending on the amplitude of the shear flow, which restricts the strength of the KH instability. For strong shear flows far above the KH instability threshold, the linear electrostatic-type KH instability saturates and achieves a vortex flow dominated quasi-steady state of the electromagnetic (EM) KH turbulence with large-amplitude zonal flows as well as zonal fields. The magnetic surfaces are twisted significantlymore » due to strong vortices but without the formation of magnetic islands. However, for the shear flow just over the KH instability threshold, a weak EM-type KH instability is saturated and remarkably damped by zonal flows through modifying the equilibrium shear flow. Interestingly, a secondary double tearing mode (DTM) is excited subsequently in highly damped KH turbulence, behaving as a pure DTM in a flowing plasma as described in Mao et al. [Phys. Plasmas 21, 052304 (2014)]. However, the explosive growth phenomenon is replaced by a gradually growing oscillation due to the extremely twisted islands. As a result, the release of the magnetic energy becomes slow and the global magnetic reconnection tends to be gentle. A complex nonlinear interaction between the EM KH turbulence and the DTMs occurs for the medium shear flows above the KH instability threshold, turbulent EM fluctuations experience oscillatory nonlinear growth of the DTMs, finally achieves a quasi-steady state with the interplay of the fluctuations between the DTMs and the EM KH instability.« less

  18. Acoustic Analysis of Voice in Dysarthria following Stroke

    ERIC Educational Resources Information Center

    Wang, Yu-Tsai; Kent, Ray D.; Kent, Jane Finley; Duffy, Joseph R.; Thomas, Jack E.

    2009-01-01

    Although perceptual studies indicate the likelihood of voice disorders in persons with stroke, there have been few objective instrumental studies of voice dysfunction in dysarthria following stroke. This study reports automatic analysis of sustained vowel phonation for 61 speakers with stroke. The results show: (1) men with stroke and healthy…

  19. Phase Asymmetries in Normophonic Speakers: Visual Judgments and Objective Findings

    ERIC Educational Resources Information Center

    Bonilha, Heather Shaw; Deliyski, Dimitar D.; Gerlach, Terri Treman

    2008-01-01

    Purpose: To ascertain the amount of phase asymmetry of the vocal fold vibration in normophonic speakers via visualization techniques and compare findings for habitual and pressed phonations. Method: Fifty-two normophonic speakers underwent stroboscopy and high-speed videoendoscopy (HSV). The HSV images were further processed into 4 visual…

  20. DIAGNOSIS AND APPRAISAL OF COMMUNICATION DISORDERS. PRENTICE-HALL FOUNDATIONS OF SPEECH PATHOLOGY SERIES.

    ERIC Educational Resources Information Center

    DARLEY, FREDERIC L.

    THIS TEXT GIVES THE STUDENT AN OUTLINE OF THE BASIC PRINCIPLES OF SCIENTIFIC METHODOLOGY WHICH UNDERLIE EVALUATIVE WORK IN SPEECH DISORDERS. RATIONALE AND ASSESSMENT TECHNIQUES ARE GIVEN FOR EXAMINATION OF THE BASIC COMMUNICATION PROCESSES OF SYMBOLIZATION, RESPIRATION, PHONATION, ARTICULATION-RESONANCE, PROSODY, ASSOCIATED SENSORY AND PERCEPTUAL…

  1. Contemporary Issues in Phoneme Production by Hearing-Impaired Persons: Physiological and Acoustic Aspects.

    ERIC Educational Resources Information Center

    McGarr, Nancy S.; Whitehead, Robert

    1992-01-01

    This paper on physiologic correlates of speech production in children and youth with hearing impairments focuses specifically on the production of phonemes and includes data on respiration for speech production, phonation, speech aerodynamics, articulation, and acoustic analyses of speech by hearing-impaired persons. (Author/DB)

  2. Vocal Pitch Discrimination in the Motor System

    ERIC Educational Resources Information Center

    D'Ausilio, Alessandro; Bufalari, Ilaria; Salmas, Paola; Busan, Pierpaolo; Fadiga, Luciano

    2011-01-01

    Speech production can be broadly separated into two distinct components: Phonation and Articulation. These two aspects require the efficient control of several phono-articulatory effectors. Speech is indeed generated by the vibration of the vocal-folds in the larynx (F0) followed by "filtering" by articulators, to select certain resonant…

  3. Time-of-Travel Methods for Measuring Optical Flow on Board a Micro Flying Robot

    PubMed Central

    Vanhoutte, Erik; Mafrica, Stefano; Ruffier, Franck; Bootsma, Reinoud J.; Serres, Julien

    2017-01-01

    For use in autonomous micro air vehicles, visual sensors must not only be small, lightweight and insensitive to light variations; on-board autopilots also require fast and accurate optical flow measurements over a wide range of speeds. Using an auto-adaptive bio-inspired Michaelis–Menten Auto-adaptive Pixel (M2APix) analog silicon retina, in this article, we present comparative tests of two optical flow calculation algorithms operating under lighting conditions from 6×10−7 to 1.6×10−2 W·cm−2 (i.e., from 0.2 to 12,000 lux for human vision). Contrast “time of travel” between two adjacent light-sensitive pixels was determined by thresholding and by cross-correlating the two pixels’ signals, with measurement frequency up to 5 kHz for the 10 local motion sensors of the M2APix sensor. While both algorithms adequately measured optical flow between 25 ∘/s and 1000 ∘/s, thresholding gave rise to a lower precision, especially due to a larger number of outliers at higher speeds. Compared to thresholding, cross-correlation also allowed for a higher rate of optical flow output (99 Hz and 1195 Hz, respectively) but required substantially more computational resources. PMID:28287484

  4. Robust boundary treatment for open-channel flows in divergence-free incompressible SPH

    NASA Astrophysics Data System (ADS)

    Pahar, Gourabananda; Dhar, Anirban

    2017-03-01

    A robust Incompressible Smoothed Particle Hydrodynamics (ISPH) framework is developed to simulate specified inflow and outflow boundary conditions for open-channel flow. Being purely divergence-free, the framework offers smoothed and structured pressure distribution. An implicit treatment of Pressure Poison Equation and Dirichlet boundary condition is applied on free-surface to minimize error in velocity-divergence. Beyond inflow and outflow threshold, multiple layers of dummy particles are created according to specified boundary condition. Inflow boundary acts as a soluble wave-maker. Fluid particles beyond outflow threshold are removed and replaced with dummy particles with specified boundary velocity. The framework is validated against different cases of open channel flow with different boundary conditions. The model can efficiently capture flow evolution and vortex generation for random geometry and variable boundary conditions.

  5. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pak, S.; Sites, J.R.

    A Kaufman-type broad beam ion source, used for sputtering and etching purposes, has been operated with Ar, Kr,O/sub 2/ and N/sub 2/ gas inputs over a wide range of beam energies (200-1200 eV) and gas flow rates (1-10 sccm). The maximum ion beam current density for each gas saturates at about 2.5 mA/sq. cm. as gas flow is increased. The discharge threshold voltage necessary to produce a beam and the beam efficiency (beam current/molecular current), however, varied considerably. Kr had the lowest threshold and highest efficiency, Ar next, then N/sub 2/ and O/sub 2/. The ion beam current varied onlymore » weakly with beam energy for low gas flow rates, but showed a factor of two increase when the gas flow was higher.« less

  6. Secondary flow structures in the presence of Type-IV stent fractures through a bent tube model for curved arteries: Effect of circulation thresholding

    NASA Astrophysics Data System (ADS)

    Hussain, Shadman; Bulusu, Kartik V.; Plesniak, Michael W.

    2013-11-01

    A common treatment for atherosclerosis is the opening of narrowed arteries resulting from obstructive lesions by angioplasty and stent implantation to restore unrestricted blood flow. ``Type-IV'' stent fractures involve complete transverse, linear fracture of stent struts, along with displacement of the stent fragments. Experimental data pertaining to secondary flows in the presence of stents that underwent ``Type-IV'' fractures in a bent artery model under physiological inflow conditions were obtained through a two-component, two-dimensional (2C-2D) PIV technique. Concomitant stent-induced flow perturbations result in secondary flow structures with complex, multi-scale morphologies and varying size-strength characteristics. Ultimately, these flow structures may have a role to play in restenosis and progression of atherosclerotic plaque. Vortex circulation thresholds were established with the goal of resolving and tracking iso-circulation secondary flow vortical structures and their morphological changes. This allowed for a parametric evaluation and quantitative representation of secondary flow structures undergoing deformation and spatial reorganization. Supported by NSF Grant No. CBET- 0828903 and GW Center for Biomimetics and Bioinspired Engineering.

  7. Rainfall thresholds and susceptibility mapping for shallow landslides and debris flows in Scotland

    NASA Astrophysics Data System (ADS)

    Postance, Benjamin; Hillier, John; Dijkstra, Tom; Dixon, Neil

    2017-04-01

    Shallow translational slides and debris flows (hereafter 'landslides') pose a significant threat to life and cause significant annual economic impacts (e.g. by damage and disruption of infrastructure). The focus of this research is on the definition of objective rainfall thresholds using a weather radar system and landslide susceptibility mapping. In the study area Scotland, an inventory of 75 known landslides was used for the period 2003 to 2016. First, the effect of using different rain records (i.e. time series length) on two threshold selection techniques in receiver operating characteristic (ROC) analysis was evaluated. The results show that thresholds selected by 'Threat Score' (minimising false alarms) are sensitive to rain record length and which is not routinely considered, whereas thresholds selected using 'Optimal Point' (minimising failed alarms) are not; therefore these may be suited to establishing lower limit thresholds and be of interest to those developing early warning systems. Robust thresholds are found for combinations of normalised rain duration and accumulation at 1 and 12 day's antecedence respectively; these are normalised using the rainy-day normal and an equivalent measure for rain intensity. This research indicates that, in Scotland, rain accumulation provides a better indicator than rain intensity and that landslides may be generated by threshold conditions lower than previously thought. Second, a landslide susceptibility map is constructed using a cross-validated logistic regression model. A novel element of the approach is that landslide susceptibility is calculated for individual hillslope sections. The developed thresholds and susceptibility map are combined to assess potential hazards and impacts posed to the national highway network in Scotland.

  8. Acute hyperfibrinogenemia impairs cochlear blood flow and hearing function in guinea pigs in vivo.

    PubMed

    Ihler, Fritz; Strieth, Sebastian; Pieri, Nicos; Göhring, Peter; Canis, Martin

    2012-03-01

    Impairment of microcirculation is a possible cause of sudden sensorineural hearing loss (SSNHL). Fibrinogen is known as a risk factor for both microvascular dysfunction and SSNHL. Therefore, the aim of this study was to investigate the effect of elevated serum levels of fibrinogen on cochlear blood flow and hearing function in vivo. One group of guinea pigs received two consecutive injections of 100 mg fibrinogen while a control group received equimolar doses of albumin. Measurements of cochlear microcirculation by intravital microscopy and of hearing thresholds by auditory brainstem response (ABR) recordings were carried out before, after first and after second injection. Ten healthy guinea pigs were randomly assigned to a treatment group or a control group of five animals each. Serum fibrinogen levels were elevated after the first and second injections of fibrinogen compared to basal values and control group respectively. Increasing levels of fibrinogen were paralleled by decreasing cochlear blood flow as well as increasing hearing thresholds. Hearing threshold correlated negatively with cochlear blood flow. The effect of microcirculatory impairment on hearing function could be explained by a malfunction of the cochlear amplifier. Further investigation is needed to quantify cochlear potentials under elevated serum fibrinogen levels.

  9. Saddle-node bifurcation to jammed state for quasi-one-dimensional counter-chemotactic flow.

    PubMed

    Fujii, Masashi; Awazu, Akinori; Nishimori, Hiraku

    2010-07-01

    The transition of a counter-chemotactic particle flow from a free-flow state to a jammed state in a quasi-one-dimensional path is investigated. One of the characteristic features of such a flow is that the constituent particles spontaneously form a cluster that blocks the path, called a path-blocking cluster (PBC), and causes a jammed state when the particle density is greater than a threshold value. Near the threshold value, the PBC occasionally collapses on itself to recover the free flow. In other words, the time evolution of the size of the PBC governs the flux of a counter-chemotactic flow. In this Rapid Communication, on the basis of numerical results of a stochastic cellular automata (SCA) model, we introduce a Langevin equation model for the size evolution of the PBC that reproduces the qualitative characteristics of the SCA model. The results suggest that the emergence of the jammed state in a quasi-one-dimensional counterflow is caused by a saddle-node bifurcation.

  10. Radar-based quantitative precipitation estimation for the identification of debris flow occurrence over earthquake-affected regions in Sichuan, China

    NASA Astrophysics Data System (ADS)

    Shi, Zhao; Wei, Fangqiang; Chandrasekar, Venkatachalam

    2018-03-01

    Both Ms 8.0 Wenchuan earthquake on 12 May 2008 and Ms 7.0 Lushan earthquake on 20 April 2013 occurred in the province of Sichuan, China. In the earthquake-affected mountainous area, a large amount of loose material caused a high occurrence of debris flow during the rainy season. In order to evaluate the rainfall intensity-duration (I-D) threshold of the debris flow in the earthquake-affected area, and to fill up the observational gaps caused by the relatively scarce and low-altitude deployment of rain gauges in this area, raw data from two S-band China New Generation Doppler Weather Radar (CINRAD) were captured for six rainfall events that triggered 519 debris flows between 2012 and 2014. Due to the challenges of radar quantitative precipitation estimation (QPE) over mountainous areas, a series of improvement measures are considered: a hybrid scan mode, a vertical reflectivity profile (VPR) correction, a mosaic of reflectivity, a merged rainfall-reflectivity (R - Z) relationship for convective and stratiform rainfall, and rainfall bias adjustment with Kalman filter (KF). For validating rainfall accumulation over complex terrains, the study areas are divided into two kinds of regions by the height threshold of 1.5 km from the ground. Three kinds of radar rainfall estimates are compared with rain gauge measurements. It is observed that the normalized mean bias (NMB) is decreased by 39 % and the fitted linear ratio between radar and rain gauge observation reaches at 0.98. Furthermore, the radar-based I-D threshold derived by the frequentist method is I = 10.1D-0.52 and is underestimated by uncorrected raw radar data. In order to verify the impacts on observations due to spatial variation, I-D thresholds are identified from the nearest rain gauge observations and radar observations at the rain gauge locations. It is found that both kinds of observations have similar I-D thresholds and likewise underestimate I-D thresholds due to undershooting at the core of convective rainfall. It is indicated that improvement of spatial resolution and measuring accuracy of radar observation will lead to the improvement of identifying debris flow occurrence, especially for events triggered by the strong small-scale rainfall process in the study area.

  11. Intensive Speech and Language Therapy for Older Children with Cerebral Palsy: A Systems Approach

    ERIC Educational Resources Information Center

    Pennington, Lindsay; Miller, Nick; Robson, Sheila; Steen, Nick

    2010-01-01

    Aim: To investigate whether speech therapy using a speech systems approach to controlling breath support, phonation, and speech rate can increase the speech intelligibility of children with dysarthria and cerebral palsy (CP). Method: Sixteen children with dysarthria and CP participated in a modified time series design. Group characteristics were…

  12. The Perception of Pathologically-Disordered Phonation by Gujarati, English, and Spanish Listeners

    ERIC Educational Resources Information Center

    Esposito, Christina M.

    2011-01-01

    This study investigates the influence of linguistic experience on the perception of pathologically-disordered voices using 18 listeners of American English, which has allophonic breathiness, 12 listeners of Gujarati, which contrasts breathy and modal vowels, and 18 listeners of Spanish, which has neither allophonic nor phonemic breathiness.…

  13. Modification of Poly(vinyl butyral) Coatings Using Bis-silanes (Postprint)

    DTIC Science & Technology

    2010-04-01

    parent coating to 2-chloroethyl ethyl sulfide (2-CEES), dimethyl methylphosphonate (DMMP), diisopropyl methylphosphonate, and methyl salicylate ; the...methylphosphonate (DMMP), diisopropyl methylphos- phonate, and methyl salicylate ; the most significant reduction was observed for 2-CEES and DMMP at...dimethyl methylphosphonate (DMMP), diisopropyl methylphosphonate (DIMP), dibutyltin dilaurate (DBTDL), and methyl salicylate (MS)wereobtained

  14. Spectral Analysis of the Voice in Down Syndrome

    ERIC Educational Resources Information Center

    Albertini, G.; Bonassi, S.; Dall'Armi, V.; Giachetti, I.; Giaquinto, S.; Mignano, M.

    2010-01-01

    The voice quality of individuals with Down Syndrome (DS) is generally described as husky, monotonous and raucous. On the other hand, the voice of DS children is characterized by breathiness, roughness, and nasality and is typically low pitched. However, research on phonation and intonation in these participants is limited. The present study was…

  15. Breathing-Impaired Speech after Brain Haemorrhage: A Case Study

    ERIC Educational Resources Information Center

    Heselwood, Barry

    2007-01-01

    Results are presented from an auditory and acoustic analysis of the speech of an adult male with impaired prosody and articulation due to brain haemorrhage. They show marked effects on phonation, speech rate and articulator velocity, and a speech rhythm disrupted by "intrusive" stresses. These effects are discussed in relation to the speaker's…

  16. Ventricular-Fold Dynamics in Human Phonation

    ERIC Educational Resources Information Center

    Bailly, Lucie; Bernardoni, Nathalie Henrich; Müller, Frank; Rohlfs, Anna-Katharina; Hess, Markus

    2014-01-01

    Purpose: In this study, the authors aimed (a) to provide a classification of the ventricular-fold dynamics during voicing, (b) to study the aerodynamic impact of these motions on vocal-fold vibrations, and (c) to assess whether ventricular-fold oscillations could be sustained by aerodynamic coupling with the vocal folds. Method: A 72-sample…

  17. Vocalization Subsystem Responses to a Temporarily Induced Unilateral Vocal Fold Paralysis

    ERIC Educational Resources Information Center

    Croake, Daniel J.; Andreatta, Richard D.; Stemple, Joseph C.

    2018-01-01

    Purpose: The purpose of this study is to quantify the interactions of the 3 vocalization subsystems of respiration, phonation, and resonance before, during, and after a perturbation to the larynx (temporarily induced unilateral vocal fold paralysis) in 10 vocally healthy participants. Using dynamic systems theory as a guide, we hypothesized that…

  18. Effects of Smoking on Respiratory Capacity and Control

    ERIC Educational Resources Information Center

    Awan, Shaheen N.; Alphonso, Vania A.

    2007-01-01

    The purpose of this study was to provide information concerning the possible early effects of smoking on measures of respiratory capacity and control in young adult female smokers vs. nonsmokers. In particular, maximum performance test results (vital capacity and maximum phonation time) and measures of air pressures and airflows during voiceless,…

  19. Jaw-Phonatory Coordination in Chronic Developmental Stuttering

    ERIC Educational Resources Information Center

    Loucks, Torrey M. J.; De Nil, Luc F.; Sasisekaran, Jayanthi

    2007-01-01

    A deficiency in sensorimotor integration in a person who stutters may be a factor in the pathophysiology of developmental stuttering. To test oral sensorimotor function in adults who stutter, we used a task that requires the coordination of a jaw-opening movement with phonation onset. The task was adapted from previous limb coordination studies,…

  20. The morphometry of the laryngeal phonatory system - base of the anatomical study of the voice aptitudes.

    PubMed

    Hînganu, Marius Valeriu; Cozma, Romică Sebastian; Ciochină, Paula; Scutariu, Irina Andreea; Asimionoaiei-Simionescu, Cristina; Hînganu, Delia

    2017-01-01

    Speaking is one of the characteristics of the human race and the main factor that has marked our progress over time. The singing voice is the crowning of the speech act and the main component of the lyrical manifestation of personality. Doctors in various fields, but especially anatomists have been concerned about discovering how the voice and the substrate of its variability are formed, but these aspects have not yet been fully deciphered. This study is the starting point in our research on the phonation system, organized on three levels: laryngeal, oral, palatinal, pharyngeal, epiglottal and nasal. We performed the dissection of seven embalmed anatomical parts, on which, we made measurements of the anatomical elements involved in the phonation. We performed the same measurements on a batch of seven adults investigated by magnetic resonance imaging (MRI). The results were entered into the statistical calculation formulas and compared with each other and with the literature. The results of the study show that certain values resulting from the calculation formulas remain constant and others vary greatly from each individuals and gender.

  1. Origin of the double- and multi-pulse structure of echolocation signals in Yangtze finless porpoise (Neophocaena phocaenoides asiaeorientialis)

    NASA Astrophysics Data System (ADS)

    Li, Songhai; Wang, Kexiong; Wang, Ding; Akamatsu, Tomonari

    2005-12-01

    The signals of dolphins and porpoises often exhibit a multi-pulse structure. Here, echolocation signal recordings were made from four geometrically distinct positions of seven Yangtze finless porpoises temporarily housed in a relatively small, enclosed area. Some clicks demonstrated double-pulse, and others multi-pulse, structure. The interpulse intervals between the first and second pulse of the double- and multi-pulse clicks were significantly different among data from the four different positions (p<0.01, one-way ANOVA). These results indicate that the interpulse interval and structure of the double- and multi-pulse echolocation signals depend on the hydrophone geometry of the animal, and that the double- and multi-pulse structure of echolocation signals in Yangtze finless porpoise is not caused by the phonating porpoise itself, but by the multipath propagation of the signal. Time delays in the 180° phase-shifted surface reflection pulse and the nonphase-shifted bottom reflection pulse of the multi-pulse structures, relative to the direct signal, can be used to calculate the distance to a phonating animal.

  2. Effect of Levodopa + Carbidopa on the Laryngeal Electromyographic Pattern in Parkinson Disease.

    PubMed

    Noffs, Gustavo; de Campos Duprat, André; Zarzur, Ana Paula; Cury, Rubens Gisbert; Cataldo, Berenice Oliveira; Fonoff, Erich

    2017-05-01

    Vocal impairment is one of the main debilitating symptoms of Parkinson disease (PD). The effect of levodopa on vocal function remains unclear. This study aimed to determine the effect of levodopa on electromyographic patterns of the laryngeal muscle in patients with PD. This is a prospective interventional trial. Nineteen patients with PD-diagnosed by laryngeal electromyography-were enrolled. Cricothyroid and thyroarytenoid (TA) muscle activities were measured at rest and during muscle contraction (phonation), when participants were on and off medication (12 hours after the last levodopa dose). Prevalence of resting hypertonia in the cricothyroid muscle was similar in the off and on states (7 of 19, P = 1.00). Eight patients off medication and four patients on medication had hypertonic TA muscle at rest (P = 0.289). No electromyographic alterations were observed during phonation for either medication states. Despite a tendency for increased rest tracings in the TA muscle when participants were on medication, no association was found between laryngeal electromyography findings and levodopa + carbidopa administration. Copyright © 2017. Published by Elsevier Inc.

  3. A modeling approach to establish environmental flow threshold in ungauged semidiurnal tidal river

    NASA Astrophysics Data System (ADS)

    Akter, A.; Tanim, A. H.

    2018-03-01

    Due to shortage of flow monitoring data in ungauged semidiurnal river, 'environmental flow' (EF) determination based on its key component 'minimum low flow' is always difficult. For EF assessment this study selected a reach immediately after the Halda-Karnafuli confluence, a unique breeding ground for Indian Carp fishes of Bangladesh. As part of an ungauged tidal river, EF threshold establishment faces challenges in changing ecological paradigms with periodic change of tides and hydrologic alterations. This study describes a novel approach through modeling framework comprising hydrological, hydrodynamic and habitat simulation model. The EF establishment was conceptualized according to the hydrologic process of an ungauged semi-diurnal tidal regime in four steps. Initially, a hydrologic model coupled with a hydrodynamic model to simulate flow considering land use changes effect on streamflow, seepage loss of channel, friction dominated tidal decay as well as lack of long term flow characteristics. Secondly, to define hydraulic habitat feature, a statistical analysis on derived flow data was performed to identify 'habitat suitability'. Thirdly, to observe the ecological habitat behavior based on the identified hydrologic alteration, hydraulic habitat features were investigated. Finally, based on the combined habitat suitability index flow alteration and ecological response relationship was established. Then, the obtained EF provides a set of low flow indices of desired regime and thus the obtained discharge against maximum Weighted Usable Area (WUA) was defined as EF threshold for the selected reach. A suitable EF regime condition was obtained within flow range 25-30.1 m3/s i.e., around 10-12% of the mean annual runoff of 245 m3/s and these findings are within researchers' recommendation of minimum flow requirement. Additionally it was observed that tidal characteristics are dominant process in semi-diurnal regime. However, during the study period (2010-2015) the validated model with those reported observations can provide guidance for the decision support system (DSS) to maintain EF range in an ungauged tidal river.

  4. Modeling subsurface stormflow initiation in low-relief landscapes

    NASA Astrophysics Data System (ADS)

    Hopp, Luisa; Vaché, Kellie B.; Rhett Jackson, C.; McDonnell, Jeffrey J.

    2015-04-01

    Shallow lateral subsurface flow as a runoff generating mechanism at the hillslope scale has mostly been studied in steeper terrain with typical hillside angles of 10 - 45 degrees. These studies have shown that subsurface stormflow is often initiated at the interface between a permeable upper soil layer and a lower conductivity impeding layer, e.g. a B horizon or bedrock. Many studies have identified thresholds of event size and soil moisture states that need to be exceeded before subsurface stormflow is initiated. However, subsurface stormflow generation on low-relief hillslopes has been much less studied. Here we present a modeling study that investigates the initiation of subsurface stormflow on low-relief hillslopes in the Upper Coastal Plain of South Carolina, USA. Hillslopes in this region typically have slope angles of 2-5 degrees. Topsoils are sandy, underlain by a low-conductivity sandy clay loam Bt horizon. Subsurface stormflow has only been intercepted occasionally in a 120 m long trench, and often subsurface flow was not well correlated with stream signals, suggesting a disconnect between subsurface flow on the hillslopes and stream flow. We therefore used a hydrologic model to better understand which conditions promote the initiation of subsurface flow in this landscape, addressing following questions: Is there a threshold event size and soil moisture state for producing lateral subsurface flow? What role does the spatial pattern of depth to the impeding clay layer play for subsurface stormflow dynamics? We reproduced a section of a hillslope, for which high-resolution topographic data and depth to clay measurements were available, in the hydrologic model HYDRUS-3D. Soil hydraulic parameters were based on experimentally-derived data. The threshold analysis was first performed using hourly climate data records for 2009-2010 from the study site to drive the simulation. For this period also trench measurements of subsurface flow were available. In addition, we also ran a longer-term simulation, using daily climate data for a nine year period to include more variable climate conditions in the threshold analysis. The model captured the observed subsurface flow instances very well. The threshold analysis indicated that the occurrence of subsurface stormflow uncommon, with a large proportion of the water perching above the clay layer percolating vertically into the clay layer. Event sizes of approximately 70-80 mm were required for initiating subsurface stormflow. The hourly data from 2009-2010 was subsequently used to test if the actual spatial distribution of depth to clay is a major control for the occurrence and magnitude of lateral subsurface flow. Results suggest that in this low-relief landscape also a spatially uniform mean depth to clay reproduces well the hydrologic behavior.

  5. Voice and respiratory outcomes after permanent transoral surgery of bilateral vocal fold paralysis.

    PubMed

    Nawka, Tadeus; Sittel, Christian; Arens, Christoph; Lang-Roth, Ruth; Wittekindt, Claus; Hagen, Rudolf; Mueller, Andreas H; Nasr, Ahmed I; Guntinas-Lichius, Orlando; Friedrich, Gerhard; Gugatschka, Markus

    2015-12-01

    Bilateral vocal fold paralysis (BVFP) is a rare but life-threatening condition mostly caused by iatrogenic damage to the peripheral recurrent laryngeal nerve. Endoscopic enlargement techniques have been the standard treatment for decades. However, prospective studies using internationally accepted phoniatric and respiratory evaluation guidelines are rare. Prospective observational multicenter study. Twelve clinical centers screened 61 patients, of whom 36 were eligible according to the study protocol. Subjects were assessed with specific phoniatric and respiratory tests preoperatively and at 1 and 6 months postoperatively. Important respiratory parameters improved significantly 6 months postoperatively (peak expiratory and expiratory flow), confirming that a glottal enlargement effectively reduced the obstruction. Objective parameters dealing with voice quality worsened significantly (maximum phonation time, voice range profile, hoarseness), whereas subjective voice assessment (VHI-12) did not change significantly. Endoscopic glottal enlargement is an effective method for relieving symptoms of dyspnea due to BVFP. Postoperatively, voice quality objectively worsened; however, this was not perceived by the patients themselves. Laryngostroboscopic findings did not correlate strongly with voice and respiratory outcomes. 2b. © 2015 The American Laryngological, Rhinological and Otological Society, Inc.

  6. Change in Pulmonary Function after Incentive Spirometer Exercise in Children with Spastic Cerebral Palsy: A Randomized Controlled Study

    PubMed Central

    Choi, Ja Young; Rha, Dong-wook

    2016-01-01

    Purpose The aim of this study was to investigate the effect of incentive spirometer exercise (ISE) on pulmonary function and maximal phonation time (MPT) in children with spastic cerebral palsy (CP). Materials and Methods Fifty children with CP were randomly assigned to two groups: the experimental group and the control group. Both groups underwent comprehensive rehabilitation therapy. The experimental group underwent additional ISE. The forced vital capacity (FVC), forced expiratory volume at one second (FEV1), FEV1/FVC ratio, peak expiratory flow (PEF), and MPT were assessed as outcome measures before and after 4 weeks of training. Results There were significant improvements in FVC, FEV1, PEF, and MPT in the experimental group, but not in the control group. In addition, the improvements in FVC, FEV1, and MPT were significantly greater in the experimental group than in the control group. Conclusion The results of this randomized controlled study support the use of ISE for enhancing pulmonary function and breath control for speech production in children with CP. PMID:26996580

  7. The singer's voice range profile: female professional opera soloists.

    PubMed

    Lamarche, Anick; Ternström, Sten; Pabon, Peter

    2010-07-01

    This work concerns the collection of 30 voice range profiles (VRPs) of female operatic voice. We address the questions: Is there a need for a singer's protocol in VRP acquisition? Are physiological measurements sufficient or should the measurement of performance capabilities also be included? Can we address the female singing voice in general or is there a case for categorizing voices when studying phonetographic data? Subjects performed a series of structured tasks involving both standard speech voice protocols and additional singing tasks. Singers also completed an extensive questionnaire. Physiological VRPs differ from performance VRPs. Two new VRP metrics, the voice area above a defined level threshold and the dynamic range independent from the fundamental frequency (F(0)), were found to be useful in the analysis of singer VRPs. Task design had no effect on performance VRP outcomes. Voice category differences were mainly attributable to phonation frequency-based information. Results support the clinical importance of addressing the vocal instrument as it is used in performance. Equally important is the elaboration of a protocol suitable for the singing voice. The given context and instructions can be more important than task design for performance VRPs. Yet, for physiological VRP recordings, task design remains critical. Both types of VRPs are suggested for a singer's voice evaluation. Copyright (c) 2010 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  8. Electroglottographic parameterization of the effects of gender, vowel and phonatory registers on vocal fold vibratory patterns: an Indian perspective.

    PubMed

    Paul, Nilanjan; Kumar, Suman; Chatterjee, Indranil; Mukherjee, Biswarup

    2011-01-01

    In-depth study on laryngeal biomechanics and vocal fold vibratory patterns reveal that a single vibratory cycle can be divided into two major phases, the closed and open phase, which is subdivided into opening and closing phases. Studies reveal that the relative time course of abduction and adduction, which in turn is dependent on the relative relaxing and tensing of the vocal fold cover and body, to be the determining factor in production of a particular vocal register like the modal (or chest), falsetto, glottal fry registers. Studies further point out Electroglottography to be particularly suitable for the study of vocal vibratory patterns during register changes. However, to date, there has been limited study on quantitative parameterization of EGG wave form in vocal fry register. Moreover, contradictory findings abound in literature regarding effects of gender and vowel types on vocal vibratory patterns, especially during phonation at different registers. The present study endeavors to find out the effects of vowel and gender differences on the vocal fold vibratory patterns in different registers and how these would be reflected in standard EGG parameters of Contact Quotient (CQ) and Contact Index (CI), taking into consideration the Indian sociolinguistic context. Electroglottographic recordings of 10 young adults (5 males and 5 females) were taken while the subjects phonated the three vowels /a/,/i/,/u/ each in two vocal registers, modal and vocal fry. Obtained raw EGG were further normalized using the Derived EGG algorithm and theCQ and CI values were derived. Obtained data were subject to statistical analysis using the 3-way ANOVA with gender, vowel and vocal register as the three variables. Post-hoc Dunnett C multiple comparison analysis were also performed. Results reveal that CQ values are significantly higher in vocal fry than modal phonation for both males and females, indicating a relatively hyperconstricted vocal system during vocal fry. The males have significantly greater CQ values than females both at modal and vocal fry phonations which indicate that the males are predisposed to greater vocal fold constriction. Females demonstrated no significant increase in CI values in vocal fry state; and in some cases actually decrease in the CI values which suggest an inherently distinct vocal fold physiological adjustment from that in males. No vowel effects were found in any conditions. Perturbation values (CQP and CIP) are significantly more in vocal fry register than in modal register, and the increase was more in case of females than males. The findings give strong evidence to certain hypotheses in literature regarding effects of vowel, gender and phonatory register on vocal fold vibratory patterns.

  9. An animal model for the analysis of cochlear blood flow [corrected] disturbance and hearing threshold in vivo.

    PubMed

    Canis, Martin; Arpornchayanon, Warangkana; Messmer, Catalina; Suckfuell, Markus; Olzowy, Bernhard; Strieth, Sebastian

    2010-02-01

    Impairment of cochlear blood flow (CBF) is considered to be important in inner ear pathology. However, direct measurement of CBF is difficult and has not been investigated in combination with hearing function. Six guinea pigs were used to show feasibility of an animal model for the analysis of cochlear microcirculation by intravital microscopy in combination with investigation of the hearing threshold by brainstem response audiometry (ABR). By the application of sodium nitroprusside (SNP), CBF was increased over 30 min. Reproducibility of measurements was shown by retest measurements. Mean baseline velocity of CBF was 109 +/- 19 mum/s. Vessel diameters had a mean value of 9.4 +/- 2.7 mum. Mean hearing threshold was 19 +/- 6 dB. In response to SNP, CBF velocity increased significantly to 161 +/- 26 mum/s. Mean arterial pressure decreased significantly to 36 +/- 11 mmHg. After the end of the application, CBF velocity recovered to a minimum of 123 +/- 17 microm/s. Within the retest, CBF velocity significantly increased to a maximum of 160 +/- 31 microm/s. Second recovery of CBF velocity was 125 +/- 14 mum/s. Within the second retest, CBF increased significantly to 157 +/- 25 microm/s. ABR thresholds did not change significantly. The increase in blood flow velocity occurred in spite of substantial hypotension as induced by a vasodilator. This may explain the fact that ABR threshold remained unchanged reflecting a maintained blood supply in this part of the brain. This technique can be used to evaluate effects of treatments aimed at cochlear microcirculation in inner ear pathologies.

  10. Identifying hydrological regime and eco-flow threshold of small and medium flood of the Xiaoqing River in Jinan city

    NASA Astrophysics Data System (ADS)

    Liu, Yang; Cao, Sheng-Le

    2017-06-01

    It was known that hydrological regime was the main influencing factor of river ecosystem, but the regime of different flow rates of urban rivers was poorly understood. We collected daily inflows at the Huangtai station of the Xiaoqing River from 1960 to 2014 and divided the data into three periods. Then we calculated hydrological parameters by the method of EFCs (Environmental Flow Components) and analyzed the tendency and change rates of each component respectively in the three periods. Combined with the ecological significance of environmental flow components, we identified the small and medium flood had the greatest impact on the river regime and ecosystem. And then we used the hydraulic parameters in the good ecosystem period as control conditions, to calculate the ecological threshold of the flow component under the current situation. This study could provide technical support for restoring and improving hydrological regime and ecological environment of the Xiaoqing River in Jinan city.

  11. Catch bonds govern adhesion through L-selectin at threshold shear.

    PubMed

    Yago, Tadayuki; Wu, Jianhua; Wey, C Diana; Klopocki, Arkadiusz G; Zhu, Cheng; McEver, Rodger P

    2004-09-13

    Flow-enhanced cell adhesion is an unexplained phenomenon that might result from a transport-dependent increase in on-rates or a force-dependent decrease in off-rates of adhesive bonds. L-selectin requires a threshold shear to support leukocyte rolling on P-selectin glycoprotein ligand-1 (PSGL-1) and other vascular ligands. Low forces decrease L-selectin-PSGL-1 off-rates (catch bonds), whereas higher forces increase off-rates (slip bonds). We determined that a force-dependent decrease in off-rates dictated flow-enhanced rolling of L-selectin-bearing microspheres or neutrophils on PSGL-1. Catch bonds enabled increasing force to convert short-lived tethers into longer-lived tethers, which decreased rolling velocities and increased the regularity of rolling steps as shear rose from the threshold to an optimal value. As shear increased above the optimum, transitions to slip bonds shortened tether lifetimes, which increased rolling velocities and decreased rolling regularity. Thus, force-dependent alterations of bond lifetimes govern L-selectin-dependent cell adhesion below and above the shear optimum. These findings establish the first biological function for catch bonds as a mechanism for flow-enhanced cell adhesion.

  12. Device for monitoring cell voltage

    DOEpatents

    Doepke, Matthias [Garbsen, DE; Eisermann, Henning [Edermissen, DE

    2012-08-21

    A device for monitoring a rechargeable battery having a number of electrically connected cells includes at least one current interruption switch for interrupting current flowing through at least one associated cell and a plurality of monitoring units for detecting cell voltage. Each monitoring unit is associated with a single cell and includes a reference voltage unit for producing a defined reference threshold voltage and a voltage comparison unit for comparing the reference threshold voltage with a partial cell voltage of the associated cell. The reference voltage unit is electrically supplied from the cell voltage of the associated cell. The voltage comparison unit is coupled to the at least one current interruption switch for interrupting the current of at least the current flowing through the associated cell, with a defined minimum difference between the reference threshold voltage and the partial cell voltage.

  13. Gas ultrasonic flow rate measurement through genetic-ant colony optimization based on the ultrasonic pulse received signal model

    NASA Astrophysics Data System (ADS)

    Hou, Huirang; Zheng, Dandan; Nie, Laixiao

    2015-04-01

    For gas ultrasonic flowmeters, the signals received by ultrasonic sensors are susceptible to noise interference. If signals are mingled with noise, a large error in flow measurement can be caused by triggering mistakenly using the traditional double-threshold method. To solve this problem, genetic-ant colony optimization (GACO) based on the ultrasonic pulse received signal model is proposed. Furthermore, in consideration of the real-time performance of the flow measurement system, the improvement of processing only the first three cycles of the received signals rather than the whole signal is proposed. Simulation results show that the GACO algorithm has the best estimation accuracy and ant-noise ability compared with the genetic algorithm, ant colony optimization, double-threshold and enveloped zero-crossing. Local convergence doesn’t appear with the GACO algorithm until -10 dB. For the GACO algorithm, the converging accuracy and converging speed and the amount of computation are further improved when using the first three cycles (called GACO-3cycles). Experimental results involving actual received signals show that the accuracy of single-gas ultrasonic flow rate measurement can reach 0.5% with GACO-3 cycles, which is better than with the double-threshold method.

  14. Perception of Wet Vocal Quality in Identifying Penetration/Aspiration during Swallowing

    ERIC Educational Resources Information Center

    Groves-Wright, Kathy Jean; Boyce, Suzanne; Kelchner, Lisa

    2010-01-01

    Purpose: In the present study, the authors investigated the association between wet vocal quality (WVQ) and prandial material in the larynx during phonation. The presence of such material is indicative of oropharyngeal dysphagia and results from entry of material into the laryngeal vestibule during swallowing. The primary aim of the study was to…

  15. Magnetic Resonance Imaging Assessment of the Velopharyngeal Mechanism at Rest and during Speech in Chinese Adults and Children

    ERIC Educational Resources Information Center

    Tian, Wei; Yin, Heng; Redett, Richard J.; Shi, Bing; Shi, Jin; Zhang, Rui; Zheng, Qian

    2010-01-01

    Purpose: Recent applications of the magnetic resonance imaging (MRI) technique introduced accurate 3-dimensional measurements of the velopharyngeal mechanism. Further standardization of the data acquisition and analysis protocol was successfully applied to imaging adults at rest and during phonation. This study was designed to test and modify a…

  16. Relational Speech Timing in Dysarthria Associated with Cerebellar Lesions in Different Loci: Word Context

    ERIC Educational Resources Information Center

    Vandana, V. P.; Manjula, R.

    2006-01-01

    Cerebellum plays an important role in speech motor control. Various tasks like sustained phonation, diadochokinesis and conversation have been used to tap the speech timing abilities of dysarthric clients with cerebellar lesion. It has recently been proposed that not all areas of the cerebellum may be involved in speech motor control; especially…

  17. Effect of Bilateral Stimulation of the Subthalamic Nucleus on Different Speech Subsystems in Patients with Parkinson's Disease

    ERIC Educational Resources Information Center

    Putzer, Manfred; Barry, William J.; Moringlane, Jean Richard

    2008-01-01

    The effect of deep brain stimulation on the two speech-production subsystems, articulation and phonation, of nine Parkinsonian patients is examined. Production parameters (stop closure voicing; stop closure, VOT, vowel) in fast syllable-repetitions were defined and measured and quantitative, objective metrics of vocal fold function were obtained…

  18. Acoustic Changes in the Speech of Children with Cerebral Palsy Following an Intensive Program of Dysarthria Therapy

    ERIC Educational Resources Information Center

    Pennington, Lindsay; Lombardo, Eftychia; Steen, Nick; Miller, Nick

    2018-01-01

    Background: The speech intelligibility of children with dysarthria and cerebral palsy has been observed to increase following therapy focusing on respiration and phonation. Aims: To determine if speech intelligibility change following intervention is associated with change in acoustic measures of voice. Methods & Procedures: We recorded 16…

  19. Peripheral Mechanisms for Vocal Production in Birds--Differences and Similarities to Human Speech and Singing

    ERIC Educational Resources Information Center

    Riede, Tobias; Goller, Franz

    2010-01-01

    Song production in songbirds is a model system for studying learned vocal behavior. As in humans, bird phonation involves three main motor systems (respiration, vocal organ and vocal tract). The avian respiratory mechanism uses pressure regulation in air sacs to ventilate a rigid lung. In songbirds sound is generated with two independently…

  20. Voice Training and Therapy with a Semi-Occluded Vocal Tract: Rationale and Scientific Underpinnings

    ERIC Educational Resources Information Center

    Titze, Ingo R.

    2006-01-01

    Purpose: Voice therapy with a semi-occluded vocal tract has a long history. The use of lip trills, tongue trills, bilabial fricatives, humming, and phonation into tubes or straws has been hailed by clinicians, singing teachers, and voice coaches as efficacious for training and rehabilitation. Little has been done, however, to provide the…

  1. The Effects of Swim Training on Respiratory Aspects of Speech Production in Adolescents with Down Syndrome

    ERIC Educational Resources Information Center

    Casey, Amanda Faith; Emes, Claudia

    2011-01-01

    Reduced respiratory muscle strength in individuals with Down syndrome (DS) may affect speech respiratory variables such as maximum phonation duration (MPD), initiation volume, and expired mean airflow. Researchers randomly assigned adolescents with DS (N = 28) to either 12 weeks of swim training (DS-ST) or a control group (DS-NT). Repeated…

  2. Student Voice Use and Vocal Health during an All-State Chorus Event

    ERIC Educational Resources Information Center

    Daugherty, James F.; Manternach, Jeremy N.; Price, Kathy K.

    2011-01-01

    This field-based case study documented students' (N = 256) voice use and voice health perceptions during a 3-day all-state high school chorus event through daily surveys, phonation duration data, analysis of rehearsal voice use behaviors, and field notes. Among the primary results are the following: (a) First and final day survey comparisons…

  3. Phonation Interval Modification and Speech Performance Quality during Fluency-Inducing Conditions by Adults Who Stutter

    ERIC Educational Resources Information Center

    Ingham, Roger J.; Bothe, Anne K.; Wang, Yuedong; Purkhiser, Krystal; New, Anneliese

    2012-01-01

    Purpose: To relate changes in four variables previously defined as characteristic of normally fluent speech to changes in phonatory behavior during oral reading by persons who stutter (PWS) and normally fluent controls under multiple fluency-inducing (FI) conditions. Method: Twelve PWS and 12 controls each completed 4 ABA experiments. During A…

  4. Low-threshold high-T/0/ constricted double heterojunction AlGaAs diode lasers

    NASA Technical Reports Server (NTRS)

    Botez, D.; Connolly, J. C.

    1980-01-01

    Constricted double heterojunction diode lasers of relatively low CW thresholds (28-40 mA) are obtained by growing structures that maximize the amount of current flow into the lasing spot. These values are obtained while still using standard 10 microns wide oxide-defined stripe contacts. Over the 20-70 C temperature interval, threshold current temperature coefficients as high as 320 C and a virtually constant external differential quantum efficiency, are found.

  5. Thresholds of flow-induced bed disturbances and their effects on stream metabolism in an agricultural river

    USGS Publications Warehouse

    O'Connor, Ben L.; Harvey, Judson W.; McPhillips, Lauren E.

    2012-01-01

    Storm-driven flow pulses in rivers destroy and restructure sediment habitats that affect stream metabolism. This study examined thresholds of bed disturbances that affected patch- and reach-scale sediment conditions and metabolism rates. A 4 year record of discharge and diel changes in dissolved oxygen concentrations (ΔDO) was analyzed for disturbances and recovery periods of the ΔDO signal. Disturbances to the ΔDO signal were associated with flow pulses, and the recovery times for the ΔDO signal were found to be in two categories: less than 5 days (30% of the disturbances) or greater than 15 days (70% of the disturbances). A field study was performed during the fall of 2007, which included a storm event that increased discharge from 3.1 to 6.9 m3/s over a 7 h period. During stable flow conditions before the storm, variability in patch-scale stream metabolism values were associated with sediment texture classes with values ranging from −16.4 to 2.3 g O22/d (negative sign indicates net respiration) that bounded the reach-averaged rate of −5.6 g O22/d. Hydraulic modeling of bed shear stresses demonstrated a storm-induced flow pulse mobilized approximately 25% of the bed and reach-scale metabolism rates shifted from −5 to −40 g O22/d. These results suggest that storm-induced bed disturbances led to threshold behavior with respect to stream metabolism. Small flow pulses resulted in partial-bed mobilization that disrupted stream metabolism by increased turbidity with short recovery times. Large flow pulses resulted in full-bed mobilization that disrupted stream metabolism by destroying periphyton habitats with long recovery times.

  6. The Definition, Rationale, and Effects of Thresholding in OCT Angiography.

    PubMed

    Cole, Emily D; Moult, Eric M; Dang, Sabin; Choi, WooJhon; Ploner, Stefan B; Lee, ByungKun; Louzada, Ricardo; Novais, Eduardo; Schottenhamml, Julia; Husvogt, Lennart; Maier, Andreas; Fujimoto, James G; Waheed, Nadia K; Duker, Jay S

    2017-01-01

    To examine the definition, rationale, and effects of thresholding in OCT angiography (OCTA). A theoretical description of OCTA thresholding in combination with qualitative and quantitative analysis of the effects of OCTA thresholding in eyes from a retrospective case series. Four eyes were qualitatively examined: 1 from a 27-year-old control, 1 from a 78-year-old exudative age-related macular degeneration (AMD) patient, 1 from a 58-year-old myopic patient, and 1 from a 77-year-old nonexudative AMD patient with geographic atrophy (GA). One eye from a 75-year-old nonexudative AMD patient with GA was quantitatively analyzed. A theoretical thresholding model and a qualitative and quantitative description of the dependency of OCTA on thresholding level. Due to the presence of system noise, OCTA thresholding is a necessary step in forming OCTA images; however, thresholding can complicate the relationship between blood flow and OCTA signal. Thresholding in OCTA can cause significant artifacts, which should be considered when interpreting and quantifying OCTA images.

  7. Ion-scale turbulence in MAST: anomalous transport, subcritical transitions, and comparison to BES measurements

    NASA Astrophysics Data System (ADS)

    van Wyk, F.; Highcock, E. G.; Field, A. R.; Roach, C. M.; Schekochihin, A. A.; Parra, F. I.; Dorland, W.

    2017-11-01

    We investigate the effect of varying the ion temperature gradient (ITG) and toroidal equilibrium scale sheared flow on ion-scale turbulence in the outer core of MAST by means of local gyrokinetic simulations. We show that nonlinear simulations reproduce the experimental ion heat flux and that the experimentally measured values of the ITG and the flow shear lie close to the turbulence threshold. We demonstrate that the system is subcritical in the presence of flow shear, i.e., the system is formally stable to small perturbations, but transitions to a turbulent state given a large enough initial perturbation. We propose that the transition to subcritical turbulence occurs via an intermediate state dominated by low number of coherent long-lived structures, close to threshold, which increase in number as the system is taken away from the threshold into the more strongly turbulent regime, until they fill the domain and a more conventional turbulence emerges. We show that the properties of turbulence are effectively functions of the distance to threshold, as quantified by the ion heat flux. We make quantitative comparisons of correlation lengths, times, and amplitudes between our simulations and experimental measurements using the MAST BES diagnostic. We find reasonable agreement of the correlation properties, most notably of the correlation time, for which significant discrepancies were found in previous numerical studies of MAST turbulence.

  8. Coolant and ambient temperature control for chillerless liquid cooled data centers

    DOEpatents

    Chainer, Timothy J.; David, Milnes P.; Iyengar, Madhusudan K.; Parida, Pritish R.; Simons, Robert E.

    2016-02-02

    Cooling control methods include measuring a temperature of air provided to a plurality of nodes by an air-to-liquid heat exchanger, measuring a temperature of at least one component of the plurality of nodes and finding a maximum component temperature across all such nodes, comparing the maximum component temperature to a first and second component threshold and comparing the air temperature to a first and second air threshold, and controlling a proportion of coolant flow and a coolant flow rate to the air-to-liquid heat exchanger and the plurality of nodes based on the comparisons.

  9. Avalanches of Singing Sand in the Laboratory

    NASA Astrophysics Data System (ADS)

    Dagois-Bohy, Simon; Courrech Du Pont, Sylvain; Douady, Stéphane

    2011-03-01

    The song of dunes is a natural phenomenon that has arisen travellers' curiosity for a long time, from Marco Polo to R.A. Bagnold. Scientific observations in the XXth century have shown that the sound is emitted during a shear flow of these particular grains, the free surface of the flow having coherent vibrations like a loud speaker. The sound emission is also submitted to a threshold effect with many parameters like humidity, flow speed, surface of the grains. The sound has been reproduced in laboratory avalanche experiments close to the natural phenomenon on field, but set in a channel with a hard bottom and a few centimeters of sand flowing, which contradicts explanations of the sound that involve a sand dune under the avalanche flow. Flow rates measurements also show the presence of a plug region in the flow above the sheared band, with the same characteristic length as the coherence zones of the sound. Finally we show experimentally that the Froude number, once modified to take into account the height of this plug band, is the parameter that sets the amplitude of the sound, and produces a threshold that depends on the grain type.

  10. Operation of a real-time warning system for debris flows in the San Francisco bay area, California

    USGS Publications Warehouse

    Wilson, Raymond C.; Mark, Robert K.; Barbato, Gary; ,

    1993-01-01

    The United States Geological Survey (USGS) and the National Weather Service (NWS) have developed an operational warning system for debris flows during severe rainstorms in the San Francisco Bay region. The NWS makes quantitative forecasts of precipitation from storm systems approaching the Bay area and coordinates a regional network of radio-telemetered rain gages. The USGS has formulated thresholds for the intensity and duration of rainfall required to initiate debris flows. The first successful public warnings were issued during a severe storm sequence in February 1986. Continued operation of the warning system since 1986 has provided valuable working experience in rainfall forecasting and monitoring, refined rainfall thresholds, and streamlined procedures for issuing public warnings. Advisory statements issued since 1986 are summarized.

  11. Soil water storage, rainfall and runoff relationships in a tropical dry forest catchment

    NASA Astrophysics Data System (ADS)

    Farrick, Kegan K.; Branfireun, Brian A.

    2014-12-01

    In forested catchments, the exceedance of rainfall and antecedent water storage thresholds is often required for runoff generation, yet to our knowledge these threshold relationships remain undescribed in tropical dry forest catchments. We, therefore, identified the controls of streamflow activation and the timing and magnitude of runoff in a tropical dry forest catchment near the Pacific coast of central Mexico. During a 52 day transition phase from the dry to wet season, soil water movement was dominated by vertical flow which continued until a threshold soil moisture content of 26% was reached at 100 cm below the surface. This satisfied a 162 mm storage deficit and activated streamflow, likely through lateral subsurface flow pathways. High antecedent soil water conditions were maintained during the wet phase but had a weak influence on stormflow. We identified a threshold value of 289 mm of summed rainfall and antecedent soil water needed to generate >4 mm of stormflow per event. Above this threshold, stormflow response and magnitude was almost entirely governed by rainfall event characteristics and not antecedent soil moisture conditions. Our results show that over the course of the wet season in tropical dry forests the dominant controls on runoff generation changed from antecedent soil water and storage to the depth of rainfall.

  12. Discharge variability and bedrock river incision on the Hawaiian island of Kaua'i

    NASA Astrophysics Data System (ADS)

    Huppert, K.; Deal, E.; Perron, J. T.; Ferrier, K.; Braun, J.

    2017-12-01

    Bedrock river incision occurs during floods that generate sufficient shear stress to strip riverbeds of sediment cover and erode underlying bedrock. Thresholds for incision can prevent erosion at low flows and slow down erosion at higher flows that do generate excess shear stress. Because discharge distributions typically display power-law tails, with non-negligible frequencies of floods much greater than the mean, models incorporating stochastic discharge and incision thresholds predict that discharge variability can sometimes have greater effects on long-term incision rates than mean discharge. This occurs when the commonly observed inverse scalings between mean discharge and discharge variability are weak or when incision thresholds are high. Because the effects of thresholds and discharge variability have only been documented in a few locations, their influence on long-term river incision rates remains uncertain. The Hawaiian island of Kaua'i provides an ideal natural laboratory to evaluate the effects of discharge variability and thresholds on bedrock river incision because it has one of Earth's steepest spatial gradients in mean annual rainfall and it also experiences dramatic spatial variations in rainfall and discharge variability, spanning a wide range of the conditions reported on Earth. Kaua'i otherwise has minimal variations in lithology, vertical motion, and other factors that can influence erosion. River incision rates averaged over 1.5 - 4.5 Myr timescales can be estimated along the lengths of Kauaian channels from the depths of river canyons and lava flow ages. We characterize rainfall and discharge variability on Kaua'i using records from an extensive network of rain and stream gauges spanning the past century. We use these characterizations to model long-term bedrock river incision along Kauaian channels with a threshold-dependent incision law, modulated by site-specific discharge-channel width scalings. Our comparisons between modeled and observed erosion rates suggest that variations in river incision rates on Kaua'i are dominated by variations in mean rainfall and discharge, rather than by differences in storminess across the island. We explore the implications of this result for the threshold dependence of river incision across Earth's varied climates.

  13. Coupled prediction of flash flood response and debris flow occurrence in an alpine basin

    NASA Astrophysics Data System (ADS)

    Amponsah, William

    2015-04-01

    Coupled prediction of flash flood response and debris flow occurrence in an alpine basin Author(s): William Amponsah1, E.I. Nikolopoulos2, Lorenzo Marchi1, Roberto Dinale4, Francesco Marra3,Davide Zoccatelli2 , Marco Borga2 Affiliation(s): 1CNR - IRPI, Corso Stati Uniti 4, 35127, Padova, ITALY, 2Department of Land, Environment, Agriculture and Forestry, University of Padova,VialeDell'Università 16, 35020, Legnaro PD, ITALY 3Department of Geography, Hebrew University of Jerusalem, ISRAEL 4Ufficio Idrografico, Provincia Autonoma di Bolzano, Bolzano, Italy This contribution examines the main hydrologic and morphologic metrics responsible for widespread triggering of debris-flows associated with flash flood occurrences in headwater alpine catchments.To achieve this objective, we investigate the precipitation forcing, hydrologic responses and landslides and debris-flow occurrences that prevailed during the August 4-5, 2012 extreme flash flood on the 140 km2 Vizze basin in the Eastern Alps of Italy. An intensive post-event survey was carried out a few days after the flood. This included the surveys of cross-sectional geometry and flood marks for the estimation of the peak discharges at multiple river sections and of the initiation and deposition areas of several debris flows. Rainfall estimates are based on careful analysis of weather radar observations and raingauge data. These data and observations permitted the implementation and calibration of a spatially distributed hydrological model, which was used to derive simulated flood hydrographs in 58 tributaries of the Vizze basin. Of these, 33 generated debris-flows, with area ranging from 0.02 km2 to 10 km2, with an average of 1.5 km2. With 130 mm peak event rainfall and a duration of 4 hours (with a max intensity of 90 mm h-1 for 10 min), model-simulated unit peak discharges range from 4 m3 s-1 km-2for elementary catchments up to 10 km2 to 2 m3 s-1 km-2 for catchments in the range of 50 - 100 km2. These are very high values when considering the local runoff regime. We used a threshold criterion based on past works (Tognaccaet al., 2000; Berti and Simoni, 2005; Gregoretti and Dalla Fontana, 2008) to identify tributaries associated to debris flow events. The threshold is defined for each channel grid as a function of the simulated unit width peak flow, of the local channel bed slope and of the mean grain size. Based on assumptions concerning the mean grain size and given the distribution of the threshold values over the river network, we derive a catchment scale threshold index for the tributaries. The results show that the index has considerable skill in identifying the catchments where the studied rainstorm caused debris-flows. Berti, M. andA.Simoni, 2005: Experimental evidences and numerical modelling of debris flow initiated by channel runoff. Landslides, 2 (3), 171-182. Gregoretti, C. and G. Dalla Fontana, 2008:The triggering of debris flow due to channel-bed failure in some alpine headwater basins of the Dolomites: analyses of critical runoff. Hydrol. Process. 22, 2248-2263. Tognacca C., G.R. Bezzola andH.E.Minor, 2000: Threshold criterion fodebrisflow initiation due to channel bed failure. In Proceedings of the Second International Conference on Debris Flow Hazards Mitigation Taipei,August, Wiezczorek, Naeser (eds): 89-97.

  14. High levels of endocrine pollutants in US streams during low flow due to insufficient wastewater dilution

    NASA Astrophysics Data System (ADS)

    Rice, Jacelyn; Westerhoff, Paul

    2017-08-01

    Wastewater discharges from publicly owned treatment works are a significant source of endocrine disruptors and other contaminants to the aquatic environment in the US. Although remaining pollutants in wastewater pose environmental risks, treated wastewater is also a primary source of stream flow, which in turn is critical in maintaining many aquatic and riparian wildlife habitats. Here we calculate the dilution factor--the ratio of flow in the stream receiving discharge to the flow of wastewater discharge--for over 14,000 receiving streams in the continental US using streamflow observations and a spatially explicit watershed-scale hydraulic model. We found that wastewater discharges make up more than 50% of in-stream flow for over 900 streams. However, in 1,049 streams that experienced exceptional low-flow conditions, the dilution factors in 635 of those streams fell so low during those conditions that the safety threshold for concentrations of one endocrine disrupting compound was exceeded, and in roughly a third of those streams, the threshold was exceeded for two compounds. We suggest that streams are vulnerable to public wastewater discharge of contaminants under low-flow conditions, at a time when wastewater discharges are likely to be most important for maintaining stream flow for smaller sized river systems.

  15. Phonatory Effects of Airway Dehydration: Preliminary Evidence for Impaired Compensation to Oral Breathing in Individuals with a History of Vocal Fatigue

    ERIC Educational Resources Information Center

    Sivasankar, Mahalakshmi; Erickson, Elizabeth; Schneider, Sara; Hawes, Ashleigh

    2008-01-01

    Purpose: Airway drying is detrimental to phonation and is posited to exacerbate vocal fatigue. However, limited research has demonstrated the adverse phonatory effects of dehydration in speakers reporting vocal fatigue. We compared the negative phonatory consequences of short-term oral breathing at low, moderate, and high humidity in individuals…

  16. Voice Loudness and Gender Effects on Jitter and Shimmer in Healthy Adults

    ERIC Educational Resources Information Center

    Brockmann, Meike; Storck, Claudio; Carding, Paul N.; Drinnan, Michael J.

    2008-01-01

    Purpose: The aim of this study was to investigate voice loudness and gender effects on jitter and shimmer in healthy young adults because previous descriptions have been inconsistent. Method: Fifty-seven healthy adults (28 women, 29 men) aged 20-40 years were included in this cross-sectional single-cohort study. Three phonations of /a/ at soft,…

  17. Comparing Measures of Voice Quality From Sustained Phonation and Continuous Speech.

    PubMed

    Gerratt, Bruce R; Kreiman, Jody; Garellek, Marc

    2016-10-01

    The question of what type of utterance-a sustained vowel or continuous speech-is best for voice quality analysis has been extensively studied but with equivocal results. This study examines whether previously reported differences derive from the articulatory and prosodic factors occurring in continuous speech versus sustained phonation. Speakers with voice disorders sustained vowels and read sentences. Vowel samples were excerpted from the steadiest portion of each vowel in the sentences. In addition to sustained and excerpted vowels, a 3rd set of stimuli was created by shortening sustained vowel productions to match the duration of vowels excerpted from continuous speech. Acoustic measures were made on the stimuli, and listeners judged the severity of vocal quality deviation. Sustained vowels and those extracted from continuous speech contain essentially the same acoustic and perceptual information about vocal quality deviation. Perceived and/or measured differences between continuous speech and sustained vowels derive largely from voice source variability across segmental and prosodic contexts and not from variations in vocal fold vibration in the quasisteady portion of the vowels. Approaches to voice quality assessment by using continuous speech samples average across utterances and may not adequately quantify the variability they are intended to assess.

  18. Vocal fold tissue failure: preliminary data and constitutive modeling.

    PubMed

    Chan, Roger W; Siegmund, Thomas

    2004-08-01

    In human voice production (phonation), linear small-amplitude vocal fold oscillation occurs only under restricted conditions. Physiologically, phonation more often involves large-amplitude oscillation associated with tissue stresses and strains beyond their linear viscoelastic limits, particularly in the lamina propria extracellular matrix (ECM). This study reports some preliminary measurements of tissue deformation and failure response of the vocal fold ECM under large-strain shear The primary goal was to formulate and test a novel constitutive model for vocal fold tissue failure, based on a standard-linear cohesive-zone (SL-CZ) approach. Tissue specimens of the sheep vocal fold mucosa were subjected to torsional deformation in vitro, at constant strain rates corresponding to twist rates of 0.01, 0.1, and 1.0 rad/s. The vocal fold ECM demonstrated nonlinear stress-strain and rate-dependent failure response with a failure strain as low as 0.40 rad. A finite-element implementation of the SL-CZ model was capable of capturing the rate dependence in these preliminary data, demonstrating the model's potential for describing tissue failure. Further studies with additional tissue specimens and model improvements are needed to better understand vocal fold tissue failure.

  19. Effect of singing training on total laryngectomees wearing a tracheoesophageal voice prosthesis.

    PubMed

    Onofre, Fernanda; Ricz, Hilton Marcos Alves; Takeshita-Monaretti, Telma Kioko; Prado, Maria Yuka de Almeida; Aguiar-Ricz, Lílian Neto

    2013-02-01

    To assess the effect of a program of singing training on the voice of total laryngectomees wearing tracheoesophageal voice prosthesis, considering the quality of alaryngeal phonation, vocal extension and the musical elements of tunning and legato. Five laryngectomees wearing tracheoesophageal voice prosthesis completed the singing training program over a period of three months, with exploration of the strengthening of the respiratory muscles and vocalization and with evaluation of perceptive-auditory and singing voice being performed before and after 12 sessions of singing therapy. After the program of singing voice training, the quality of tracheoesophageal voice showed improvement or the persistence of the general degree of dysphonia for the emitted vowels and for the parameters of roughness and breathiness. For the vowel "a", the pitch was displaced to grave in two participants and to acute in one, and remained adequate in the others. A similar situation was observed also for the vowel "i". After the singing program, all participants presented tunning and most of them showed a greater presence of legato. The vocal extension improved in all participants. Singing training seems to have a favorable effect on the quality of tracheoesophageal phonation and on singing voice.

  20. A Synthetic Self-Oscillating Vocal Fold Model Platform for Studying Augmentation Injection

    PubMed Central

    Murray, Preston R.; Thomson, Scott L.; Smith, Marshall E.

    2013-01-01

    Objective Design and evaluate a platform for studying the mechanical effects of augmentation injections using synthetic self-oscillating vocal fold models. Study Design Basic science. Methods Life-sized, synthetic, multi-layer, self-oscillating vocal fold models were created that simulated bowing via volumetric reduction of the body layer relative to that of a normal, unbowed model. Material properties of the layers were unchanged. Models with varying degrees of bowing were created and paired with normal models. Following initial acquisition of data (onset pressure, vibration frequency, flow rate, and high-speed image sequences), bowed models were injected with silicone that had material properties similar to those used in augmentation procedures. Three different silicone injection quantities were tested: sufficient to close the glottal gap, insufficient to close the glottal gap, and excess silicone to create convex bowing of the bowed model. The above-mentioned metrics were again taken and compared. Pre- and post-injection high-speed image sequences were acquired using a hemilarynx setup, from which medial surface dynamics were quantified. Results The models vibrated with mucosal wave-like motion and at onset pressures and frequencies typical of human phonation. The models successfully exhibited various degrees of bowing which were then mitigated by injecting filler material. The models showed general pre- to post-injection decreases in onset pressure, flow rate, and open quotient, and a corresponding increase in vibration frequency. Conclusion The model may be useful in further explorations of the mechanical consequences of augmentation injections. PMID:24476985

  1. Exploring the role of flood transience in coarse bed load sediment transport

    NASA Astrophysics Data System (ADS)

    Phillips, C. B.; Singer, M. B.; Hill, K. M.; Paola, C.

    2015-12-01

    The rate of bed load transport under steady flow is known to vary both spatially and temporally due to various hydrologic and granular phenomena. Grain size distributions and riverbed properties (packing, imbrication, etc.) are known to affect flux for a particular value of applied flow stress, while hydrology is mainly assumed to control the magnitude of the applied bed stress above the threshold for bed material entrainment. The prediction of bed load sediment transport in field settings is further complicated by the inherent transience in flood hydrology, but little is known about how such flood transience influences bed load flux over a range of applied bed stress. Here we investigate the role of flood transience for gravel bed load transport through controlled laboratory experiments in a 28 m long 0.5 meter wide flume. We explore transient flow as the combination of unsteady and intermittent flow, where unsteady flow varies in magnitude over a given duration, and intermittent flow is characterized by turning the flow on and off. We systematically vary these details of flood hydrographs from one experiment to the next, and monitor the bed load as it varies with water discharge in real time by measuring sediment flux and tracking particles. We find that even with a narrow unimodal grain size distribution and constant sediment supply we observe hysteresis in bed load flux, different thresholds for entrainment and distrainment for the rising and falling limbs of a flood, and a threshold of entrainment that can vary one flood hydrograph to the next. Despite these complex phenomena we find that the total bed load transported for each flood plots along a linear trend with the integrated excess stress, consistent with prior field results. These results suggest that while the effects of transient flow and the shape of the hydrograph are measurable, they are second-order compared to the integrated excess stress.

  2. Fuel cell flooding detection and correction

    DOEpatents

    DiPierno Bosco, Andrew; Fronk, Matthew Howard

    2000-08-15

    Method and apparatus for monitoring an H.sub.2 -O.sub.2 PEM fuel cells to detect and correct flooding. The pressure drop across a given H.sub.2 or O.sub.2 flow field is monitored and compared to predetermined thresholds of unacceptability. If the pressure drop exists a threshold of unacceptability corrective measures are automatically initiated.

  3. Granular motions near the threshold of entrainment

    NASA Astrophysics Data System (ADS)

    Valyrakis, Manousos; Alexakis, athanasios-Theodosios

    2016-04-01

    Our society is continuously impacted by significant weather events many times resulting in catastrophes that interrupt our normal way of life. In the context of climate change and increasing urbanisation these "extreme" hydrologic events are intensified both in magnitude and frequency, inducing costs of the order of billions of pounds. The vast majority of such costs and impacts (even more to developed societies) are due to water related catastrophes such as the geomorphic action of flowing water (including scouring of critical infrastructure, bed and bank destabilisation) and flooding. New tools and radically novel concepts are in need, to enable our society becoming more resilient. This presentation, emphasises the utility of inertial sensors in gaining new insights on the interaction of flow hydrodynamics with the granular surface at the particle scale and for near threshold flow conditions. In particular, new designs of the "smart-sphere" device are discussed with focus on the purpose specific sets of flume experiments, designed to identify the exact response of the particle resting at the bed surface for various below, near and above threshold flow conditions. New sets of measurements are presented for particle entrainment from a Lagrangian viewpoint. Further to finding direct application in addressing real world challenges in the water sector, it is shown that such novel sensor systems can also help the research community (both experimentalists and computational modellers) gain a better insight on the underlying processes governing granular dynamics.

  4. Stress-strain analysis of jejunal contractility in response to flow and ramp distension in type 2 diabetic GK rats: effect of carbachol stimulation.

    PubMed

    Zhao, Jingbo; Chen, Pengmin; Gregersen, Hans

    2013-09-27

    Investigation of intestinal motility in a genetic model of GK rats abandons the possible neurotoxic effect of streptozotocin in streptozotocin-induced diabetic model. Seven GK male rats (GK group) and nine normal Wistar rats (Normal group) were used in the study. The motility experiments were carried out in an organ bath containing physiological Krebs solution. Before and after 10(-5)M carbachol application, the pressure and diameter changes of jejunum were obtained in relation to (1) basic contraction, (2) flow-induced contraction with different outlet resistance pressures and (3) contractions induced by ramp distension. The frequency and amplitude of contractions were analyzed from pressure-diameter curves. Distension-induced contraction thresholds and maximum contraction amplitude of basic and flow-induced contractions were calculated in terms of stress and strain. (1) The contraction amplitude increased to the peak value in less than 10s after adding carbachol. More than two peaks were observed in the GK group. (2) Carbachol decreased the pressure and stress threshold and Young's modulus in the GK group (P<0.01). (3) Carbachol increased the maximum pressure and stress of flow-induced contractions at most outlet pressure levels in both two groups (P<0.001). Furthermore, the flow-induced contractions were significantly bigger at low outlet pressure levels in GK group (P<0.05 and P<0.01). (4) The contraction frequency, the strain threshold and the maximum contraction strain did not differ between the two groups (P>0.05) and between before and after carbachol application (P>0.05). In GK diabetic rats, the jejunal contractility was hypersensitive to flow and distension stimulation after carbachol application. Copyright © 2013 Elsevier Ltd. All rights reserved.

  5. Efficacy of the ejector flow-meter. A scavenging device for anaesthetic gases.

    PubMed

    Obel, D; Jørgensen, S; Ferguson, A; Frandsen, K

    1985-01-01

    Measurements of air concentrations of nitrous oxide and halothane in the breathing zone of the anaesthetist and the operating-room nurse were carried out during inhalation anaesthesia with a Mapleson D system. Gas removal was performed from inside the breathing system at the same rate as that of the fresh gas inflow by means of an ejector flow-meter. The concentrations of nitrous oxide and halothane were maintained below the Danish Threshold Limit Values of 100 and 5 parts per million, respectively, by using this type of scavenging. When these anaesthetics were used simultaneously, the reduced Threshold Limit Values were not exceeded during endotracheal anaesthesia.

  6. Coolant and ambient temperature control for chillerless liquid cooled data centers

    DOEpatents

    Chainer, Timothy J.; David, Milnes P.; Iyengar, Madhusudan K.; Parida, Pritish R.; Simons, Robert E.

    2017-08-29

    Cooling control methods and systems include measuring a temperature of air provided to one or more nodes by an air-to-liquid heat exchanger; measuring a temperature of at least one component of the one or more nodes and finding a maximum component temperature across all such nodes; comparing the maximum component temperature to a first and second component threshold and comparing the air temperature to a first and second air threshold; and controlling a proportion of coolant flow and a coolant flow rate to the air-to-liquid heat exchanger and the one or more nodes based on the comparisons.

  7. A renewal jump-diffusion process with threshold dividend strategy

    NASA Astrophysics Data System (ADS)

    Li, Bo; Wu, Rong; Song, Min

    2009-06-01

    In this paper, we consider a jump-diffusion risk process with the threshold dividend strategy. Both the distributions of the inter-arrival times and the claims are assumed to be in the class of phase-type distributions. The expected discounted dividend function and the Laplace transform of the ruin time are discussed. Motivated by Asmussen [S. Asmussen, Stationary distributions for fluid flow models with or without Brownian noise, Stochastic Models 11 (1) (1995) 21-49], instead of studying the original process, we study the constructed fluid flow process and their closed-form formulas are obtained in terms of matrix expression. Finally, numerical results are provided to illustrate the computation.

  8. System and method for quench and over-current protection of superconductor

    DOEpatents

    Huang, Xianrui; Laskaris, Evangelos Trifon; Sivasubramaniam, Kiruba Haran; Bray, James William; Ryan, David Thomas; Fogarty, James Michael; Steinbach, Albert Eugene

    2005-05-31

    A system and method for protecting a superconductor. The system may comprise a current sensor operable to detect a current flowing through the superconductor. The system may comprise a coolant temperature sensor operable to detect the temperature of a cryogenic coolant used to cool the superconductor to a superconductive state. The control circuit is operable to estimate the superconductor temperature based on the current flow and the coolant temperature. The system may also be operable to compare the estimated superconductor temperature to at least one threshold temperature and to initiate a corrective action when the superconductor temperature exceeds the at least one threshold temperature.

  9. Modification of turbulence and turbulent transport associated with a confinement transition in LAPD

    NASA Astrophysics Data System (ADS)

    Carter, Troy

    2009-11-01

    Azimuthal flow is driven in the edge of the Large Plasma Device (LAPD) through biasing a section of the vacuum vessel relative to the plasma source cathode. As the applied bias exceeds a threshold, a transition in radial particle confinement is observed, evidenced by a dramatic steepening in the density profile, similar to the L- to H-mode transition in toroidal confinement devices. The threshold behavior and dynamic behavior of radial transport is related to flow penetration and the degree of spatial overlap between the flow shear and density gradient profiles. An investigation of the changes in turbulence and turbulent particle transport associated with the confinement transition is presented. Two-dimensional cross-correlation measurements show that the spatial coherence of edge turbulence in LAPD changes significantly with biasing. The azimuthal correlation in the turbulence increases dramatically, while the radial correlation length is little altered. Turbulent amplitude is reduced at the transition, particularly in electric field fluctuations, but the dominant change observed is in the cross-phase between density and electric field fluctuations. The changes in cross-phase lead to a suppression and then apparent reversal of turbulent particle flux as the threshold is exceeded.

  10. Flow noise of an underwater vector sensor embedded in a flexible towed array.

    PubMed

    Korenbaum, Vladimir I; Tagiltsev, Alexander A

    2012-05-01

    The objective of this work is to simulate the flow noise of a vector sensor embedded in a flexible towed array. The mathematical model developed, based on long-wavelength analysis of the inner space of a cylindrical multipole source, predicts the reduction of the flow noise of a vector sensor embedded in an underwater flexible towed array by means of intensimetric processing (cross-spectral density calculation of oscillatory velocity and sound-pressure-sensor responses). It is found experimentally that intensimetric processing results in flow noise reduction by 12-25 dB at mean levels and by 10-30 dB in fluctuations compared to a squared oscillatory velocity channel. The effect of flow noise suppression in the intensimetry channel relative to a squared sound pressure channel is observed, but only for frequencies above the threshold. These suppression values are 10-15 dB at mean noise levels and 3-6 dB in fluctuations. At towing velocities of 1.5-3 ms(-1) and an accumulation time of 98.3 s, the threshold frequency in fluctuations is between 30 and 45 Hz.

  11. Calibration of optical coherence tomography angiography with a microfluidic chip

    NASA Astrophysics Data System (ADS)

    Su, Johnny P.; Chandwani, Rahul; Gao, Simon S.; Pechauer, Alex D.; Zhang, Miao; Wang, Jie; Jia, Yali; Huang, David; Liu, Gangjun

    2016-08-01

    A microfluidic chip with microchannels ranging from 8 to 96 μm was used to mimic blood vessels down to the capillary level. Blood flow within the microfluidic channels was analyzed with split-spectrum amplitude-decorrelation angiography (SSADA)-based optical coherence tomography (OCT) angiography. It was found that the SSADA decorrelation value was related to both blood flow speed and channel width. SSADA could differentiate nonflowing blood inside the microfluidic channels from static paper. The SSADA decorrelation value was approximately linear with blood flow velocity up to a threshold Vsat of 5.83±1.33 mm/s (mean±standard deviation over the range of channel widths). Beyond this threshold, it approached a saturation value Dsat. Dsat was higher for wider channels, and approached a maximum value Dsm as the channel width became much larger than the beam focal spot diameter. These results indicate that decorrelation values (flow signal) in capillary networks would be proportional to both flow velocity and vessel caliber but would be capped at a saturation value in larger blood vessels. These findings are useful for interpretation and quantification of clinical OCT angiography results.

  12. Self similarities in desalination dynamics and performance using capacitive deionization.

    PubMed

    Ramachandran, Ashwin; Hemmatifar, Ali; Hawks, Steven A; Stadermann, Michael; Santiago, Juan G

    2018-09-01

    Charge transfer and mass transport are two underlying mechanisms which are coupled in desalination dynamics using capacitive deionization (CDI). We developed simple reduced-order models based on a mixed reactor volume principle which capture the coupled dynamics of CDI operation using closed-form semi-analytical and analytical solutions. We use the models to identify and explore self-similarities in the dynamics among flow rate, current, and voltage for CDI cell operation including both charging and discharging cycles. The similarity approach identifies the specific combination of cell (e.g. capacitance, resistance) and operational parameters (e.g. flow rate, current) which determine a unique effluent dynamic response. We here demonstrate self-similarity using a conventional flow between CDI (fbCDI) architecture, and we hypothesize that our similarity approach has potential application to a wide range of designs. We performed an experimental study of these dynamics and used well-controlled experiments of CDI cell operation to validate and explore limits of the model. For experiments, we used a CDI cell with five electrode pairs and a standard flow between (electrodes) architecture. Guided by the model, we performed a series of experiments that demonstrate natural response of the CDI system. We also identify cell parameters and operation conditions which lead to self-similar dynamics under a constant current forcing function and perform a series of experiments by varying flowrate, currents, and voltage thresholds to demonstrate self-similarity. Based on this study, we hypothesize that the average differential electric double layer (EDL) efficiency (a measure of ion adsorption rate to EDL charging rate) is mainly dependent on user-defined voltage thresholds, whereas flow efficiency (measure of how well desalinated water is recovered from inside the cell) depends on cell volumes flowed during charging, which is determined by flowrate, current and voltage thresholds. Results of experiments strongly support this hypothesis. Results show that cycle efficiency and salt removal for a given flowrate and current are maximum when average EDL and flow efficiencies are approximately equal. We further explored a range of CC operations with varying flowrates, currents, and voltage thresholds using our similarity variables to highlight trade-offs among salt removal, energy, and throughput performance. Copyright © 2018 Elsevier Ltd. All rights reserved.

  13. On flows of viscoelastic fluids under threshold-slip boundary conditions

    NASA Astrophysics Data System (ADS)

    Baranovskii, E. S.

    2018-03-01

    We investigate a boundary-value problem for the steady isothermal flow of an incompressible viscoelastic fluid of Oldroyd type in a 3D bounded domain with impermeable walls. We use the Fujita threshold-slip boundary condition. This condition states that the fluid can slip along a solid surface when the shear stresses reach a certain critical value; otherwise the slipping velocity is zero. Assuming that the flow domain is not rotationally symmetric, we prove an existence theorem for the corresponding slip problem in the framework of weak solutions. The proof uses methods for solving variational inequalities with pseudo-monotone operators and convex functionals, the method of introduction of auxiliary viscosity, as well as a passage-to-limit procedure based on energy estimates of approximate solutions, Korn’s inequality, and compactness arguments. Also, some properties and estimates of weak solutions are established.

  14. Mechanism behind Erosive Bursts In Porous Media.

    PubMed

    Jäger, R; Mendoza, M; Herrmann, H J

    2017-09-22

    Erosion and deposition during flow through porous media can lead to large erosive bursts that manifest as jumps in permeability and pressure loss. Here we reveal that the cause of these bursts is the reopening of clogged pores when the pressure difference between two opposite sites of the pore surpasses a certain threshold. We perform numerical simulations of flow through porous media and compare our predictions to experimental results, recovering with excellent agreement shape and power-law distribution of pressure loss jumps, and the behavior of the permeability jumps as a function of particle concentration. Furthermore, we find that erosive bursts only occur for pressure gradient thresholds within the range of two critical values, independent of how the flow is driven. Our findings provide a better understanding of sudden sand production in oil wells and breakthrough in filtration.

  15. Probability modeling of high flow extremes in Yingluoxia watershed, the upper reaches of Heihe River basin

    NASA Astrophysics Data System (ADS)

    Li, Zhanling; Li, Zhanjie; Li, Chengcheng

    2014-05-01

    Probability modeling of hydrological extremes is one of the major research areas in hydrological science. Most basins in humid and semi-humid south and east of China are concerned for probability modeling analysis of high flow extremes. While, for the inland river basin which occupies about 35% of the country area, there is a limited presence of such studies partly due to the limited data availability and a relatively low mean annual flow. The objective of this study is to carry out probability modeling of high flow extremes in the upper reach of Heihe River basin, the second largest inland river basin in China, by using the peak over threshold (POT) method and Generalized Pareto Distribution (GPD), in which the selection of threshold and inherent assumptions for POT series are elaborated in details. For comparison, other widely used probability distributions including generalized extreme value (GEV), Lognormal, Log-logistic and Gamma are employed as well. Maximum likelihood estimate is used for parameter estimations. Daily flow data at Yingluoxia station from 1978 to 2008 are used. Results show that, synthesizing the approaches of mean excess plot, stability features of model parameters, return level plot and the inherent independence assumption of POT series, an optimum threshold of 340m3/s is finally determined for high flow extremes in Yingluoxia watershed. The resulting POT series is proved to be stationary and independent based on Mann-Kendall test, Pettitt test and autocorrelation test. In terms of Kolmogorov-Smirnov test, Anderson-Darling test and several graphical diagnostics such as quantile and cumulative density function plots, GPD provides the best fit to high flow extremes in the study area. The estimated high flows for long return periods demonstrate that, as the return period increasing, the return level estimates are probably more uncertain. The frequency of high flow extremes exhibits a very slight but not significant decreasing trend from 1978 to 2008, while the intensity of such flow extremes is comparatively increasing especially for the higher return levels.

  16. Recherche d'une politique de gestion des stocks d'eau de barrages-réservoirs en vue de soutenir les étiages. 1. Élaboration d'un modèle alterné annuel apports-déficits

    NASA Astrophysics Data System (ADS)

    Bocquillon, C.; Masson, J. M.

    1983-01-01

    Lack of water supply during periods of deficient flow affects the economic potentiality of the great river valleys which are the most developed areas in the country. Reservoir dams built in the upper stream catchments store excess flow and provide controlled release in the dry season. Capital costs of construction and the consequences of failures justify a thorough study of operating rules. The low flows and conditional variability of availability of water call for carry-over procedures (reservoir capacity is sometimes greater than the mean available water). It is not possible to predict future sequence of flows, thus the carry-over rule is a statistical decision-making tool. The flow data are only one of the very many possible sources of information. But the analysis of flow data provides us with statistical measures to generate long series of synthetic inflows associated with summer deficits. A simplification has been introduced by choosing only the values which are absolutely necessary for optimal management research: available water volumes and reserve volumes for a flow threshold. Yearly alternate periods of excess and deficiency of water are defined by the values above and below a threshold of flow discharge at a location gage named "objective point", where the reservoir effects are to be estimated. Yearly periods are described by water volumes, either inflows into reservoirs, or deficits below various thresholds of summer flow discharges. Marginal and conditional probability distributions of these volumes and the physical laws which mark their bounds and relationships were estimated on the basis of 31 years of daily flow records. The synthetic simulated series for 1000 years was compared to records of historical levels (since 1863). Extreme events such as sequences of dry years, have return periods of comparable magnitude. This synthetic series has a similar statistical character of short historical series and makes the analysis of operating rules possible.

  17. Finite Element Modeling of Magnetically-Damped Convection during Solidification

    NASA Technical Reports Server (NTRS)

    deGroh, H. C.; Li, B. Q.; Lu, X.

    1998-01-01

    A fully 3-D, transient finite element model is developed to represent the magnetic damping effects on complex fluid flow, heat transfer and electromagnetic field distributions in a Sn- 35.5%Pb melt undergoing unidirectional solidification. The model is developed based on our in- house finite element code for the fluid flow, heat transfer and electromagnetic field calculations. The numerical model is tested against numerical and experimental results for water as reported in literature. Various numerical simulations are carried out for the melt convection and temperature distribution with and without the presence of a transverse magnetic field. Numerical results show that magnetic damping can be effectively applied to stabilize melt flow, reduce turbulence and flow levels in the melt and over a certain threshold value a higher magnetic field resulted in a greater reduction in velocity. Also, for the study of melt flow instability, a long enough running time is needed to ensure the final fluid flow recirculation pattern. Moreover, numerical results suggest that there seems to exist a threshold value of applied magnetic field, above which magnetic damping becomes possible and below which the 0 convection in the melt is actually enhanced.

  18. Electrokinetic instability in microchannel ferrofluid/water co-flows

    PubMed Central

    Song, Le; Yu, Liandong; Zhou, Yilong; Antao, Asher Reginald; Prabhakaran, Rama Aravind; Xuan, Xiangchun

    2017-01-01

    Electrokinetic instability refers to unstable electric field-driven disturbance to fluid flows, which can be harnessed to promote mixing for various electrokinetic microfluidic applications. This work presents a combined numerical and experimental study of electrokinetic ferrofluid/water co-flows in microchannels of various depths. Instability waves are observed at the ferrofluid and water interface when the applied DC electric field is beyond a threshold value. They are generated by the electric body force that acts on the free charge induced by the mismatch of ferrofluid and water electric conductivities. A nonlinear depth-averaged numerical model is developed to understand and simulate the interfacial electrokinetic behaviors. It considers the top and bottom channel walls’ stabilizing effects on electrokinetic flow through the depth averaging of three-dimensional transport equations in a second-order asymptotic analysis. This model is found accurate to predict both the observed electrokinetic instability patterns and the measured threshold electric fields for ferrofluids of different concentrations in shallow microchannels. PMID:28406228

  19. Derivation of debris flow critical rainfall thresholds from land stability modeling

    NASA Astrophysics Data System (ADS)

    Papa, M. N.; Medina, V.; Bateman, A.; Ciervo, F.

    2012-04-01

    The aim of the work is to develop a system capable of providing debris flow warnings in areas where historical events data are not available as well as in the case of changing environments and climate. For these reasons, critical rainfall threshold curves are derived from mathematical and numerical simulations rather than the classical derivation from empirical rainfall data. The operational use of distributed model, based on the stability analysis for each grid cell of the basin, is not feasible in the case of warnings due to the long running time required for this kind of model as well as the lack of detailed information on the spatial distribution of the properties of the material in many practical cases. Moreover, with the aim of giving debris flow warnings, it is not necessary to know the distribution of instable elements along the basin but only if a debris flow may affect the vulnerable areas in the valley. The capability of a debris flow of reaching the downstream areas depends on many factors linked with the topography, the solid concentration, the rheological properties of the debris mixture and the flow discharge as well as the occurrence of liquefaction of the sliding mass. In relation to a specific basin, many of these factors may be considered as not time dependent. The most rainfall dependent factors are flow discharge and correlated total debris volume. In the present study, the total volume that is instable, and therefore available for the flow, is considered as the governing factor from which it is possible to assess whether a debris flow will affect the downstream areas or not. The possible triggering debris flow is simulated, in a generic element of the basin, by an infinite slope stability analysis. The groundwater pressure is calculated by the superposition of the effect of an "antecedent" rainfall and an "event" rainfall. The groundwater pressure response to antecedent rainfall is used as the initial condition for the time-dependent computation of the groundwater pressure response to the event rainfall. Antecedent rainfall response is estimated in the hypotheses of low intensity and long duration, thus assuming steady state conditions and slope parallel groundwater flux. The short term response to rainfall is assessed in the hypothesis of vertical infiltration. The simulations are performed in a virtual basin, representative of the one studied, taking into account the uncertainties linked with the definition of the characteristics of the soil. The approach presented is based on the simulation of a large number of cases covering the entire range of the governing input dynamic variables. For any possible combination of rainfall intensity, duration and antecedent rain, the total debris volume, available for the flow, is estimated. The resulting database is elaborated in order to obtain rainfall threshold curves. When operating in real time, if the observed and forecasted rainfall exceeds a given threshold, the corresponding probability of debris flow occurrence may be estimated.

  20. Fractal Approach to Erosion Threshold of Bentonites

    NASA Astrophysics Data System (ADS)

    Xu, Y. F.; Li, X. Y.

    Bentonite has been considered as a candidate buffer material for the disposal of high-level radioactive waste (HLW) because of its low permeability, high sorption capacity, self-sealing characteristics and durability in a natural environment. Bentonite erosion caused by groundwater flow may take place at the interface of the compacted bentonite and fractured granite. Surface erosion of bentonite flocs is represented typically as an erosion threshold. Predicting the erosion threshold of bentonite flocs requires taking into account cohesion, which results from interactions between clay particles. Beyond the usual dependence on grain size, a significant correlation between erosion threshold and porosity measurements is confirmed for bentonite flocs. A fractal model for erosion threshold of bentonite flocs is proposed. Cohesion forces, the long-range van der Waals interaction between two clay particles are taken as the resource of the erosion threshold. The model verification is conducted by the comparison with experiments published in the literature. The results show that the proposed model for erosion threshold is in good agreement with the experimental data.

  1. Approximating a nonlinear advanced-delayed equation from acoustics

    NASA Astrophysics Data System (ADS)

    Teodoro, M. Filomena

    2016-10-01

    We approximate the solution of a particular non-linear mixed type functional differential equation from physiology, the mucosal wave model of the vocal oscillation during phonation. The mathematical equation models a superficial wave propagating through the tissues. The numerical scheme is adapted from the work presented in [1, 2, 3], using homotopy analysis method (HAM) to solve the non linear mixed type equation under study.

  2. An investigation of abdominal muscle recruitment for sustained phonation in 25 healthy singers.

    PubMed

    Macdonald, Ian; Rubin, John S; Blake, Ed; Hirani, Shashi; Epstein, Ruth

    2012-11-01

    The purpose of this study was to investigate the baseline muscle thickness and recruitment patterns of the transversus abdominis muscle (TAM) and the internal oblique muscle (IOM) during semisupine phonation in a group of healthy performers. This was a 2 × 3×2 within-group, repeated-measure study in which 25 professional vocalists--12 male and 13 female performed a series of sustained pitches in differing vocal qualities. Measurements were taken with ultrasound (Sonosite Micromaxx Ultrasound System) of the baseline thickness and % recruitment during voicing, of two deep abdominal muscles--TAM and the IOM. Correlations between TAM and IOM absolute change scores, TAM and IOM percentage change scores, and changes in muscle thickness (absolute and percentage) and age were examined using Spearman's correlations. Gender differences in the four types of change scores within each combination of pitch and quality were conducted with one-way analysis of variances. Differences in muscle thickness change 1) absolute scores and 2) percentage change in TAM and IOM, by pitch and quality (and their interactions) were analyzed using linear mixed models, using restricted maximum likelihood estimations, employing a Toeplitz variance-covariance matrix structure in SPSS (IBM, 2011). Post hoc analyses for independent variable group differences used Sidak's correction for multiple comparisons. Alpha level was set to 0.05. In terms of absolute contractions (changes in the actual millimeter thickness of the muscle), the IOM was greater than the TAM. However in terms of percentage changes in muscles during phonation, the TAM was always greater than the IOM. The TAM as a percentage change was recruited preferentially and significantly in most vocal qualities tested. Although there were differences in muscle mass and recruitment patterns between genders, and males had thicker muscle mass at rest, differences due to muscle mass were not conclusive. Overall this study supports the argument that the peri-abdominal muscles do indeed play a role in supporting the "performing" or athletic voice in healthy subjects, and will hopefully act as a database for further research in individuals with healthy and injured voices. Copyright © 2012 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  3. Influence of glottal closure on the phonatory process in ex vivo porcine larynges.

    PubMed

    Birk, Veronika; Kniesburges, Stefan; Semmler, Marion; Berry, David A; Bohr, Christopher; Döllinger, Michael; Schützenberger, Anne

    2017-10-01

    Many cases of disturbed voice signals can be attributed to incomplete glottal closure, vocal fold oscillation asymmetries, and aperiodicity. Often these phenomena occur simultaneously and interact with each other, making a systematic, isolated investigation challenging. Therefore, ex vivo porcine experiments were performed which enable direct control of glottal configurations. Different pre-phonatory glottal gap sizes, adduction levels, and flow rates were adjusted. The resulting glottal closure types were identified in a post-processing step. Finally, the acoustic quality, aerodynamic parameters, and the characteristics of vocal fold oscillation were analyzed in reference to the glottal closure types. Results show that complete glottal closure stabilizes the phonation process indicated through a reduced left-right phase asymmetry, increased amplitude and time periodicity, and an increase in the acoustic quality. Although asymmetry and periodicity parameter variation covers only a small range of absolute values, these small variations have a remarkable influence on the acoustic quality. Due to the fact that these parameters cannot be influenced directly, the authors suggest that the (surgical) reduction of the glottal gap seems to be a promising method to stabilize the phonatory process, which has to be confirmed in future studies.

  4. Predicting the onset of high-frequency self-excited oscillations in a channel with an elastic wall

    NASA Astrophysics Data System (ADS)

    Ward, Thomas; Whittaker, Robert

    2016-11-01

    Flow-induced oscillations of fluid-conveying elastic-walled channels arise in many industrial and biological systems including the oscillation of the vocal cords during phonation. We derive a system of equations that describes the wall displacement in response to the steady and oscillatory components of the fluid pressure derived by Whittaker et al. (2010). We show that the steady pressure component results in a base state deformation assumed to be small in magnitude relative to the length of the channel. The oscillation frequency of the elastic wall is determined by an eigenvalue problem paramterised by the shape of the base state deformation, the strength of axial tension relative to azimuthal bending, F , and the size of non-linear stretching effects from the wall's initial deformation, K . We determine the slow growth or decay of the normal modes in each by considering the energy budget of the system. The amplitude of the oscillations grow or decay exponentially with a growth rate Λ, which may be expressed in terms of a critical Reynolds number Rec . We use numerical simulations to identify three distinct regions in parameter regimes space and determine the stability of oscillations in each.

  5. The Acoustic Correlates of Breathy Voice: a Study of Source-Vowel INTERACTION{00}{00}{00}{00}{00}{00}{00} {00}{00}{00}{00}{00}{00}{00}{00}{00}{00}{00}{00}{00}{00} {00}{00}{00}{00}{00}{00}{00}{00}{00}{00}{00}{00}{00}{00} {00}{00}{00}{00}{00}{00}{00}{00}{00}{00}{00}{00}{00}{00}.

    NASA Astrophysics Data System (ADS)

    Lin, Yeong-Fen Emily

    This thesis is the result of an investigation of the source-vowel interaction from the point of view of perception. Major objectives include the identification of the acoustic correlates of breathy voice and the disclosure of the interdependent relationship between the perception of vowel identity and breathiness. Two experiments were conducted to achieve these objectives. In the first experiment, voice samples from one control group and seven patient groups were compared. The control group consisted of five female and five male adults. The ten normals were recruited to perform a sustained vowel phonation task with constant pitch and loudness. The voice samples of seventy patients were retrieved from a hospital data base, with vowels extracted from sentences repeated by patients at their habitual pitch and loudness. The seven patient groups were divided, based on a unique combination of patients' measures on mean flow rate and glottal resistance. Eighteen acoustic variables were treated with a three-way (Gender x Group x Vowel) ANOVA. Parameters showing a significant female-male difference as well as group differences, especially those between the presumed breathy group and the other groups, were identified as relevant to the distinction of breathy voice. As a result, F1-F3 amplitude difference and slope were found to be most effective in distinguishing breathy voice. Other acoustic correlates of breathy voice included F1 bandwidth, RMS-H1 amplitude difference, and F1-F2 amplitude difference and slope. In the second experiment, a formant synthesizer was used to generate vowel stimuli with varying spectral tilt and F1 bandwidth. Thirteen native American English speakers made dissimilarity judgements on paired stimuli in terms of vowel identity and breathiness. Listeners' perceptual vowel spaces were found to be affected by changes in the acoustic correlates of breathy voice. The threshold of detecting a change of vocal quality in the breathiness domain was also found to be vowel-dependent.

  6. A ram-pressure threshold for star formation

    NASA Astrophysics Data System (ADS)

    Whitworth, A. P.

    2016-05-01

    In turbulent fragmentation, star formation occurs in condensations created by converging flows. The condensations must be sufficiently massive, dense and cool to be gravitationally unstable, so that they start to contract; and they must then radiate away thermal energy fast enough for self-gravity to remain dominant, so that they continue to contract. For the metallicities and temperatures in local star-forming clouds, this second requirement is only met robustly when the gas couples thermally to the dust, because this delivers the capacity to radiate across the full bandwidth of the continuum, rather than just in a few discrete spectral lines. This translates into a threshold for vigorous star formation, which can be written as a minimum ram pressure PCRIT ˜ 4 × 10-11 dyne. PCRIT is independent of temperature, and corresponds to flows with molecular hydrogen number density n_{{H_2.FLOW}} and velocity vFLOW satisfying n_{{H_2.FLOW}} v_{FLOW}^2≳ 800 cm^{-3} (km s^{-1})^2. This in turn corresponds to a minimum molecular hydrogen column density for vigorous star formation, N_{{H_2.CRIT}} ˜ 4 × 10^{21} cm^{-2} (ΣCRIT ˜ 100 M⊙ pc-2), and a minimum visual extinction AV, CRIT ˜ 9 mag. The characteristic diameter and line density for a star-forming filament when this threshold is just exceeded - a sweet spot for local star formation regions - are 2RFIL ˜ 0.1 pc and μFIL ˜ 13 M⊙ pc-2. The characteristic diameter and mass for a prestellar core condensing out of such a filament are 2RCORE ˜ 0.1 pc and MCORE ˜ 1 M⊙. We also show that fragmentation of a shock-compressed layer is likely to commence while the convergent flows creating the layer are still ongoing, and we stress that, under this circumstance, the phenomenology and characteristic scales for fragmentation of the layer are fundamentally different from those derived traditionally for pre-existing layers.

  7. Peaks Over Threshold (POT): A methodology for automatic threshold estimation using goodness of fit p-value

    NASA Astrophysics Data System (ADS)

    Solari, Sebastián.; Egüen, Marta; Polo, María. José; Losada, Miguel A.

    2017-04-01

    Threshold estimation in the Peaks Over Threshold (POT) method and the impact of the estimation method on the calculation of high return period quantiles and their uncertainty (or confidence intervals) are issues that are still unresolved. In the past, methods based on goodness of fit tests and EDF-statistics have yielded satisfactory results, but their use has not yet been systematized. This paper proposes a methodology for automatic threshold estimation, based on the Anderson-Darling EDF-statistic and goodness of fit test. When combined with bootstrapping techniques, this methodology can be used to quantify both the uncertainty of threshold estimation and its impact on the uncertainty of high return period quantiles. This methodology was applied to several simulated series and to four precipitation/river flow data series. The results obtained confirmed its robustness. For the measured series, the estimated thresholds corresponded to those obtained by nonautomatic methods. Moreover, even though the uncertainty of the threshold estimation was high, this did not have a significant effect on the width of the confidence intervals of high return period quantiles.

  8. Dielectrophoretic systems without embedded electrodes

    DOEpatents

    Cummings, Eric B [Livermore, CA; Singh, Anup K [San Francisco, CA

    2006-03-21

    Method and apparatus for dielectrophoretic separation of particles in a fluid based using array of insulating structures arranged in a fluid flow channel. By utilizing an array of insulating structures, a spatially inhomogeneous electric field is created without the use of the embedded electrodes conventionally employed for dielectrophoretic separations. Moreover, by using these insulating structures a steady applied electric field has been shown to provide for dielectrophoresis in contrast to the conventional use of an alternating electric field. In a uniform array of posts, dielectrophoretic effects have been produced flows having significant pressure-driven and electrokinetic transport. Above a threshold applied electric field, filaments of concentrated and rarefied particles appear in the flow as a result of dielectrophoresis. Above a higher threshold applied voltage, dielectrophoresis produces zones of highly concentrated and immobilized particles. These patterns are strongly influenced by the angle of the array of insulating structures with respect to the mean applied electric field and the shape of the insulating structures.

  9. Decay rates of magnetic modes below the threshold of a turbulent dynamo.

    PubMed

    Herault, J; Pétrélis, F; Fauve, S

    2014-04-01

    We measure the decay rates of magnetic field modes in a turbulent flow of liquid sodium below the dynamo threshold. We observe that turbulent fluctuations induce energy transfers between modes with different symmetries (dipolar and quadrupolar). Using symmetry properties, we show how to measure the decay rate of each mode without being restricted to the one with the smallest damping rate. We observe that the respective values of the decay rates of these modes depend on the shape of the propellers driving the flow. Dynamical regimes, including field reversals, are observed only when the modes are both nearly marginal. This is in line with a recently proposed model.

  10. Absolute versus convective helical magnetorotational instability in a Taylor-Couette flow.

    PubMed

    Priede, Jānis; Gerbeth, Gunter

    2009-04-01

    We analyze numerically the magnetorotational instability of a Taylor-Couette flow in a helical magnetic field [helical magnetorotational instability (HMRI)] using the inductionless approximation defined by a zero magnetic Prandtl number (Pr_{m}=0) . The Chebyshev collocation method is used to calculate the eigenvalue spectrum for small-amplitude perturbations. First, we carry out a detailed conventional linear stability analysis with respect to perturbations in the form of Fourier modes that corresponds to the convective instability which is not in general self-sustained. The helical magnetic field is found to extend the instability to a relatively narrow range beyond its purely hydrodynamic limit defined by the Rayleigh line. There is not only a lower critical threshold at which HMRI appears but also an upper one at which it disappears again. The latter distinguishes the HMRI from a magnetically modified Taylor vortex flow. Second, we find an absolute instability threshold as well. In the hydrodynamically unstable regime before the Rayleigh line, the threshold of absolute instability is just slightly above the convective one although the critical wavelength of the former is noticeably shorter than that of the latter. Beyond the Rayleigh line the lower threshold of absolute instability rises significantly above the corresponding convective one while the upper one descends significantly below its convective counterpart. As a result, the extension of the absolute HMRI beyond the Rayleigh line is considerably shorter than that of the convective instability. The absolute HMRI is supposed to be self-sustained and, thus, experimentally observable without any external excitation in a system of sufficiently large axial extension.

  11. A Physically Based Distributed Hydrologic Model with a no-conventional terrain analysis

    NASA Astrophysics Data System (ADS)

    Rulli, M.; Menduni, G.; Rosso, R.

    2003-12-01

    A physically based distributed hydrological model is presented. Starting from a contour-based terrain analysis, the model makes a no-conventional discretization of the terrain. From the maximum slope lines, obtained using the principles of minimum distance and orthogonality, the models obtains a stream tubes structure. The implemented model automatically can find the terrain morphological characteristics, e.g. peaks and saddles, and deal with them respecting the stream flow. Using this type of discretization, the model divides the elements in which the water flows in two classes; the cells, that are mixtilinear polygons where the overland flow is modelled as a sheet flow and channels, obtained by the interception of two or more stream tubes and whenever surface runoff occurs, the surface runoff is channelised. The permanent drainage paths can are calculated using one of the most common methods: threshold area, variable threshold area or curvature. The subsurface flow is modelled using the Simplified Bucket Model. The model considers three type of overland flow, depending on how it is produced:infiltration excess;saturation of superficial layer of the soil and exfiltration of sub-surface flow from upstream. The surface flow and the subsurface flow across a element are routed according with the mono-dimensional equation of the kinematic wave. The also model considers the spatial variability of the channels geometry with the flow. The channels have a rectangular section with length of the base decreasing with the distance from the outlet and depending on a power of the flow. The model was tested on the Rio Gallina and Missiaga catchments and the results showed model good performances.

  12. Effect of particle stiffness on contact dynamics and rheology in a dense granular flow

    NASA Astrophysics Data System (ADS)

    Bharathraj, S.; Kumaran, V.

    2018-01-01

    Dense granular flows have been well described by the Bagnold rheology, even when the particles are in the multibody contact regime and the coordination number is greater than 1. This is surprising, because the Bagnold law should be applicable only in the instantaneous collision regime, where the time between collisions is much larger than the period of a collision. Here, the effect of particle stiffness on rheology is examined. It is found that there is a rheological threshold between a particle stiffness of 104-105 for the linear contact model and 105-106 for the Hertzian contact model above which Bagnold rheology (stress proportional to square of the strain rate) is valid and below which there is a power-law rheology, where all components of the stress and the granular temperature are proportional to a power of the strain rate that is less then 2. The system is in the multibody contact regime at the rheological threshold. However, the contact energy per particle is less than the kinetic energy per particle above the rheological threshold, and it becomes larger than the kinetic energy per particle below the rheological threshold. The distribution functions for the interparticle forces and contact energies are also analyzed. The distribution functions are invariant with height, but they do depend on the contact model. The contact energy distribution functions are well fitted by Gamma distributions. There is a transition in the shape of the distribution function as the particle stiffness is decreased from 107 to 106 for the linear model and 108 to 107 for the Hertzian model, when the contact number exceeds 1. Thus, the transition in the distribution function correlates to the contact regime threshold from the binary to multibody contact regime, and is clearly different from the rheological threshold. An order-disorder transition has recently been reported in dense granular flows. The Bagnold rheology applies for both the ordered and disordered states, even though the rheological constants differ by orders of magnitude. The effect of particle stiffness on the order-disorder transition is examined here. It is found that when the particle stiffness is above the rheological threshold, there is an order-disorder transition as the base roughness is increased. The order-disorder transition disappears after the crossover to the soft-particle regime when the particle stiffness is decreased below the rheological threshold, indicating that the transition is a hard-particle phenomenon.

  13. Effect of particle stiffness on contact dynamics and rheology in a dense granular flow.

    PubMed

    Bharathraj, S; Kumaran, V

    2018-01-01

    Dense granular flows have been well described by the Bagnold rheology, even when the particles are in the multibody contact regime and the coordination number is greater than 1. This is surprising, because the Bagnold law should be applicable only in the instantaneous collision regime, where the time between collisions is much larger than the period of a collision. Here, the effect of particle stiffness on rheology is examined. It is found that there is a rheological threshold between a particle stiffness of 10^{4}-10^{5} for the linear contact model and 10^{5}-10^{6} for the Hertzian contact model above which Bagnold rheology (stress proportional to square of the strain rate) is valid and below which there is a power-law rheology, where all components of the stress and the granular temperature are proportional to a power of the strain rate that is less then 2. The system is in the multibody contact regime at the rheological threshold. However, the contact energy per particle is less than the kinetic energy per particle above the rheological threshold, and it becomes larger than the kinetic energy per particle below the rheological threshold. The distribution functions for the interparticle forces and contact energies are also analyzed. The distribution functions are invariant with height, but they do depend on the contact model. The contact energy distribution functions are well fitted by Gamma distributions. There is a transition in the shape of the distribution function as the particle stiffness is decreased from 10^{7} to 10^{6} for the linear model and 10^{8} to 10^{7} for the Hertzian model, when the contact number exceeds 1. Thus, the transition in the distribution function correlates to the contact regime threshold from the binary to multibody contact regime, and is clearly different from the rheological threshold. An order-disorder transition has recently been reported in dense granular flows. The Bagnold rheology applies for both the ordered and disordered states, even though the rheological constants differ by orders of magnitude. The effect of particle stiffness on the order-disorder transition is examined here. It is found that when the particle stiffness is above the rheological threshold, there is an order-disorder transition as the base roughness is increased. The order-disorder transition disappears after the crossover to the soft-particle regime when the particle stiffness is decreased below the rheological threshold, indicating that the transition is a hard-particle phenomenon.

  14. Unifying Suspension and Granular flows near Jamming

    NASA Astrophysics Data System (ADS)

    DeGiuli, Eric; Wyart, Matthieu

    2017-06-01

    Rheological properties of dense flows of hard particles are singular as one approaches the jamming threshold where flow ceases, both for granular flows dominated by inertia, and for over-damped suspensions. Concomitantly, the lengthscale characterizing velocity correlations appears to diverge at jamming. Here we review a theoretical framework that gives a scaling description of stationary flows of frictionless particles. Our analysis applies both to suspensions and inertial flows of hard particles. We report numerical results in support of the theory, and show the phase diagram that results when friction is added, delineating the regime of validity of the frictionless theory.

  15. Effects of carbogen on cochlear blood flow and hearing function following acute acoustic trauma in guinea pigs.

    PubMed

    Zhao, Jing; Sun, Jianjun; Liu, Yang

    2012-10-01

    Disturbances of microcirculation and hemorheological changes in the inner ear are the results of noise-induced hearing loss (NIHL). Both the disturbances of microcirculation and hemorheological changes are the etiologies of NIHL development, but they are also the results. Although previous reports that inhalation of high concentration of CO(2) may increase cochlear blood flow (CoBF), the effects of carbogen on the cochlear microcirculation and NIHL remain unclear. Changes induced by noise, carbogen and pure oxygen within the cochlear lateral wall microvasculature and in hearing thresholds were observed in guinea pigs using intravital microscopy and the auditory brainstem response. At the same time, arterial oxygen saturation and morphologic changes of cochlear hair cells were observed. Carbogen inhalation increased vessel diameters and blood flow velocities. Hearing thresholds elevation in the carbogen group was smaller than those in the control and oxygen group (p <0.05). Carbogen inhalation produced a trend toward less threshold shift after noise exposure, which reached statistical significance after day 3 (p <0.01). Respiratory acidosis was not found in our study. The segmented basal membranes of Corti in three groups indicated that no losses or discorders of hair cells were found. Carbogen inhalation can preserve hearing in animal models after acute acoustic trauma. Copyright © 2012 IMSS. All rights reserved.

  16. Measurement of xenon plasma properties in an ion thruster using laser Thomson scattering technique

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yamamoto, N.; Tomita, K.; Sugita, K.

    2012-07-15

    This paper reports on the development of a method for measuring xenon plasma properties using the laser Thomson scattering technique, for application to ion engine system design. The thresholds of photo-ionization of xenon plasma were investigated and the number density of metastable atoms, which are photo-ionized by a probe laser, was measured using laser absorption spectroscopy, for several conditions. The measured threshold energy of the probe laser using a plano-convex lens with a focal length of 200 mm was 150 mJ for a xenon mass flow rate of 20 {mu}g/s and incident microwave power of 6 W; the probe lasermore » energy was therefore set as 80 mJ. Electron number density was found to be (6.2 {+-} 0.4) Multiplication-Sign 10{sup 17} m{sup -3} and electron temperature was found to be 2.2 {+-} 0.4 eV at a xenon mass flow rate of 20 {mu}g/s and incident microwave power of 6 W. The threshold of the probe laser intensity against photo-ionization in a miniature xenon ion thruster is almost constant for various mass flow rates, since the ratio of population of the metastable atoms to the electron number density is little changed.« less

  17. Channel Bank Cohesion and the Maintenance of Suspension Rivers

    NASA Astrophysics Data System (ADS)

    Dunne, K. B. J.; Jerolmack, D. J.

    2017-12-01

    Gravel-bedded rivers organize their channel geometry and grain size such that transport is close to the threshold of motion at bankfull. Sand-bedded rivers, however, typically maintain bankfull fluid shear (or Shields) stresses far in excess of threshold; there is no widely accepted explanation for these "suspension rivers". We propose that all alluvial rivers are at the threshold of motion for their erosion-limiting material, i.e., the structural component of the river cross-section that is most difficult to mobilize. The entrainment threshold of gravel is large enough that bank cohesion has little influence on gravel-bed rivers. Sand, however, is the most easily entrained material; silt and clay can raise the entrainment threshold of sand by orders of magnitude. We examine a global dataset of river channel geometry and show that the shear stress range for sand-bedded channels is entirely within the range of entrainment thresholds for sand-mud mixtures - suggesting that rivers that suspend their sandy bed material are still threshold rivers in terms of bank material. We then present new findings from a New Jersey coastal-plain river examining if and how river-bank toe composition controls hydraulic geometry. We consider the toe because it is the foundation of the river bank, and its erosion leads to channel widening. Along a 20-km profile of the river we measure cross-section geometry, bed slope, and bed and bank composition, and we explore multiple methods of measuring the threshold shear stress of the the river-bank toe in-situ. As the composition of the river bed transitions from gravel to sand, we see preliminary evidence of a shift from bed-threshold to bank-threshold control on hydraulic geometry. We also observe that sub-bankfull flows are insufficient to erode (cohesive) bank materials, even though transport of sand is active at nearly all flows. Our findings highlight the importance of focusing on river-bank toe material, which in the studied stream is always submerged. The toe is more compacted and more resistant to erosion than the subaerially-exposed upper bank. We find mounting evidence that sand-bedded rivers are much like gravel-bedded river; they are near-threshold channels in which the suspended load does not play a controlling role in the determination of equilibrium hydraulic geometry.

  18. Environmental controls on sap flow in black locust forest in Loess Plateau, China.

    PubMed

    Ma, Changkun; Luo, Yi; Shao, Mingan; Li, Xiangdong; Sun, Lin; Jia, Xiaoxu

    2017-10-13

    Black locust accounts for over 90% of artificial forests in China's Loess Plateau region. However, water use of black locust is an uphill challenge for this semi-arid region. To accurately quantify tree water use and to explain the related hydrological processes, it is important to collect reliable data for application in the estimation of sap flow and its response to environmental factors. This study measured sap flow in black locust in the 2015 and 2016 growth seasons using the thermal dissipation probes technique and laboratory-calibrated Granier's equation. The study showed that the laboratory calibrated coefficient α was much larger than the original value presented by Granier, while the coefficient β was similar to the original one. The average daily transpiration was 2.1 mm day -1 for 2015 and 1.6 mm day -1 for 2016. Net solar radiation (Rn) was the key meteorological factor controlling sap flow, followed by vapor pressure deficit (VPD) and then temperature (T). VPD had a threshold control on sap flow at threshold values of 1.9 kPa for 2015 and 1.6 kPa for 2016. The effects of diurnal hysteresis of Rn, VPD and T on sap flow were evident, indicating that black locust water use was conservative.

  19. Numerical study on the impact of ground heating and ambient wind speed on flow fields in street canyons

    NASA Astrophysics Data System (ADS)

    Li, Lei; Yang, Lin; Zhang, Li-Jie; Jiang, Yin

    2012-11-01

    The impact of ground heating on flow fields in street canyons under different ambient wind speed conditions was studied based on numerical methods. A series of numerical tests were performed, and three factors including height-to-width (H/W) ratio, ambient wind speed and ground heating intensity were taken into account. Three types of street canyon with H/W ratios of 0.5, 1.0 and 2.0, respectively, were used in the simulation and seven speed values ranging from 0.0 to 3.0 m s-1 were set for the ambient wind speed. The ground heating intensity, which was defined as the difference between the ground temperature and air temperature, ranged from 10 to 40 K with an increase of 10 K in the tests. The results showed that under calm conditions, ground heating could induce circulation with a wind speed of around 1.0 m s-1, which is enough to disperse pollutants in a street canyon. It was also found that an ambient wind speed threshold may exist for street canyons with a fixed H/W ratio. When ambient wind speed was lower than the threshold identified in this study, the impact of the thermal effect on the flow field was obvious, and there existed a multi-vortex flow pattern in the street canyon. When the ambient wind speed was higher than the threshold, the circulation pattern was basically determined by dynamic effects. The tests on the impact of heating intensity showed that a higher ground heating intensity could strengthen the vortical flow within the street canyon, which would help improve pollutant diffusion capability in street canyons.

  20. Augmentation surgery on the cartilaginous portion of the vocal fold in a patient with cricoarytenoid joint ankylosis.

    PubMed

    Fukahori, Mioko; Chitose, Shun-Ichi; Sato, Kiminori; Kamimura, Hiroyuki; Sato, Kiminobu; On, Ririko; Umeno, Hirohito

    2018-08-01

    Surgical management of cricoarytenoid joint (CAJ) ankylosis is challenging and has the risk of worsening voice quality. In the present case, augmentation surgery was performed on the cartilaginous portion of the vocal fold in a patient with CAJ ankylosis. A 24-year-old man sustained blunt trauma to the anterior neck three years prior to developing severe breathiness. Posterior glottal insufficiency resulting from lateral fixation of the right vocal fold was observed during phonation under laryngoscopy. In addition, electromyography and CT scan revealed severe ankylosis of the right CAJ. Type I thyroplasty performed on the right vocal fold did not improve postoperative vocal function. Therefore, augmentation surgery on the cartilaginous portion of the right vocal fold was performed via endolaryngeal microsurgery under general anesthesia with jet ventilation. A piece of temporalis fascia was autotransplanted into the submucosal space created at the posterior cartilaginous portion of the right vocal fold. This resulted in the narrowing of the posterior glottal gap during phonation, leading to improvement in hoarseness. Microsurgical management with autologous fascia augmentation of the cartilaginous portion of the vocal fold can be effective in patients with lateral vocal fold fixation due to CAJ ankylosis. Copyright © 2017 Elsevier B.V. All rights reserved.

  1. Freddie Mercury-acoustic analysis of speaking fundamental frequency, vibrato, and subharmonics.

    PubMed

    Herbst, Christian T; Hertegard, Stellan; Zangger-Borch, Daniel; Lindestad, Per-Åke

    2017-04-01

    Freddie Mercury was one of the twentieth century's best-known singers of commercial contemporary music. This study presents an acoustical analysis of his voice production and singing style, based on perceptual and quantitative analysis of publicly available sound recordings. Analysis of six interviews revealed a median speaking fundamental frequency of 117.3 Hz, which is typically found for a baritone voice. Analysis of voice tracks isolated from full band recordings suggested that the singing voice range was 37 semitones within the pitch range of F#2 (about 92.2 Hz) to G5 (about 784 Hz). Evidence for higher phonations up to a fundamental frequency of 1,347 Hz was not deemed reliable. Analysis of 240 sustained notes from 21 a-cappella recordings revealed a surprisingly high mean fundamental frequency modulation rate (vibrato) of 7.0 Hz, reaching the range of vocal tremor. Quantitative analysis utilizing a newly introduced parameter to assess the regularity of vocal vibrato corroborated its perceptually irregular nature, suggesting that vibrato (ir)regularity is a distinctive feature of the singing voice. Imitation of subharmonic phonation samples by a professional rock singer, documented by endoscopic high-speed video at 4,132 frames per second, revealed a 3:1 frequency locked vibratory pattern of vocal folds and ventricular folds.

  2. Andreas Vesalius' 500th Anniversary: Initial Integral Understanding of Voice Production.

    PubMed

    Brinkman, Romy J; Hage, J Joris

    2017-01-01

    Voice production relies on the integrated functioning of a three-part system: respiration, phonation and resonance, and articulation. To commemorate the 500th anniversary of the great anatomist Andreas Vesalius (1515-1564), we report on his understanding of this integral system. The text of Vesalius' masterpiece De Humani Corporis Fabrica Libri Septum and an eyewitness report of the public dissection of three corpses by Vesalius in Bologna, Italy, in 1540, were searched for references to the voice-producing anatomical structures and their function. We clustered the traced, separate parts for the first time. We found that Vesalius recognized the importance for voice production of many details of the respiratory system, the voice box, and various structures of resonance and articulation. He stressed that voice production was a cerebral function and extensively recorded the innervation of the voice-producing organs by the cranial nerves. Vesalius was the first to publicly record the concept of voice production as an integrated and cerebrally directed function of respiration, phonation and resonance, and articulation. In doing so nearly 500 years ago, he laid a firm basis for the understanding of the physiology of voice production and speech and its management as we know it today. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  3. Jaw-phonatory coordination in chronic developmental stuttering.

    PubMed

    Loucks, Torrey M J; De Nil, Luc F; Sasisekaran, Jayanthi

    2007-01-01

    A deficiency in sensorimotor integration in a person who stutters may be a factor in the pathophysiology of developmental stuttering. To test oral sensorimotor function in adults who stutter, we used a task that requires the coordination of a jaw-opening movement with phonation onset. The task was adapted from previous limb coordination studies, which show that movement coordination depends on intact proprioception. We hypothesized that adult stutterers would show deficient jaw-phonatory coordination relative to control participants. The task required initiation of phonation as a jaw-opening movement passed through a narrow spatial target. Target amplitude and jaw movement speed were varied. The stuttering group showed significantly higher movement error and spatial variability in jaw-phonatory coordination compared to the control group, but group differences in movement velocity or duration were not found. The aberrant jaw-phonatory coordination of the stuttering participants suggests that stuttering is associated with an oral proprioceptive limitation, although, the findings are also consistent with a motor control deficit. As a result of this activity, reader will (1) learn about a hypothesis and evidence supporting the view that a sensorimotor deficit contributes to chronic developmental stuttering and (2) will obtain information about the role of proprioception in multi-articulatory coordination and how it can be tested using an oral-phonatory coordination task.

  4. Non-contact measurement of facial surface vibration patterns during singing by scanning laser Doppler vibrometer.

    PubMed

    Kitamura, Tatsuya; Ohtani, Keisuke

    2015-01-01

    This paper presents a method of measuring the vibration patterns on facial surfaces by using a scanning laser Doppler vibrometer (LDV). The surfaces of the face, neck, and body vibrate during phonation and, according to Titze (2001), these vibrations occur when aerodynamic energy is efficiently converted into acoustic energy at the glottis. A vocalist's vibration velocity patterns may therefore indicate his or her phonatory status or singing skills. LDVs enable laser-based non-contact measurement of the vibration velocity and displacement of a certain point on a vibrating object, and scanning LDVs permit multipoint measurements. The benefits of scanning LDVs originate from the facts that they do not affect the vibrations of measured objects and that they can rapidly measure the vibration patterns across planes. A case study is presented herein to demonstrate the method of measuring vibration velocity patterns with a scanning LDV. The objective of the experiment was to measure the vibration velocity differences between the modal and falsetto registers while three professional soprano singers sang sustained vowels at four pitch frequencies. The results suggest that there is a possibility that pitch frequency are correlated with vibration velocity. However, further investigations are necessary to clarify the relationships between vibration velocity patterns and phonation status and singing skills.

  5. Non-contact measurement of facial surface vibration patterns during singing by scanning laser Doppler vibrometer

    PubMed Central

    Kitamura, Tatsuya; Ohtani, Keisuke

    2015-01-01

    This paper presents a method of measuring the vibration patterns on facial surfaces by using a scanning laser Doppler vibrometer (LDV). The surfaces of the face, neck, and body vibrate during phonation and, according to Titze (2001), these vibrations occur when aerodynamic energy is efficiently converted into acoustic energy at the glottis. A vocalist's vibration velocity patterns may therefore indicate his or her phonatory status or singing skills. LDVs enable laser-based non-contact measurement of the vibration velocity and displacement of a certain point on a vibrating object, and scanning LDVs permit multipoint measurements. The benefits of scanning LDVs originate from the facts that they do not affect the vibrations of measured objects and that they can rapidly measure the vibration patterns across planes. A case study is presented herein to demonstrate the method of measuring vibration velocity patterns with a scanning LDV. The objective of the experiment was to measure the vibration velocity differences between the modal and falsetto registers while three professional soprano singers sang sustained vowels at four pitch frequencies. The results suggest that there is a possibility that pitch frequency are correlated with vibration velocity. However, further investigations are necessary to clarify the relationships between vibration velocity patterns and phonation status and singing skills. PMID:26579054

  6. The effect of an artificially lengthened vocal tract on estimated glottal contact quotient in untrained male voices.

    PubMed

    Gaskill, Christopher S; Erickson, Molly L

    2010-01-01

    The use of hard-walled narrow tubes, often called resonance tubes, for the purpose of voice therapy and voice training has a historical precedent and some theoretical support, but the mechanism of any potential benefit from the application of this technique is not well understood. Fifteen vocally untrained male participants produced a series of spoken /a/ vowels at a modal pitch and constant loudness, before and after a minute of repeated phonation into a 50-cm hard-walled glass tube at the same pitch and loudness targets. Electroglottography was used to measure the glottal contact quotient (CQ) during each phase of the experiment. Single-subject analysis revealed statistically significant changes in CQ during tube phonation, but with no discernable pattern across the 15 participants. These results indicate that the use of resonance tubes can have a distinct effect on glottal closure, but the mechanism behind this change remains unclear. The implication is that vocal loading techniques such as this need to be studied further with specific attention paid to the underlying mechanism of any measured changes in glottal behavior, and especially to the role of instruction and feedback in the therapeutic and pedagogical application of these techniques. Copyright 2010 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  7. Whispering - The hidden side of auditory communication.

    PubMed

    Frühholz, Sascha; Trost, Wiebke; Grandjean, Didier

    2016-11-15

    Whispering is a unique expression mode that is specific to auditory communication. Individuals switch their vocalization mode to whispering especially when affected by inner emotions in certain social contexts, such as in intimate relationships or intimidating social interactions. Although this context-dependent whispering is adaptive, whispered voices are acoustically far less rich than phonated voices and thus impose higher hearing and neural auditory decoding demands for recognizing their socio-affective value by listeners. The neural dynamics underlying this recognition especially from whispered voices are largely unknown. Here we show that whispered voices in humans are considerably impoverished as quantified by an entropy measure of spectral acoustic information, and this missing information needs large-scale neural compensation in terms of auditory and cognitive processing. Notably, recognizing the socio-affective information from voices was slightly more difficult from whispered voices, probably based on missing tonal information. While phonated voices elicited extended activity in auditory regions for decoding of relevant tonal and time information and the valence of voices, whispered voices elicited activity in a complex auditory-frontal brain network. Our data suggest that a large-scale multidirectional brain network compensates for the impoverished sound quality of socially meaningful environmental signals to support their accurate recognition and valence attribution. Copyright © 2016 Elsevier Inc. All rights reserved.

  8. Automated measurement of vocal fold vibratory asymmetry from high-speed videoendoscopy recordings.

    PubMed

    Mehta, Daryush D; Deliyski, Dimitar D; Quatieri, Thomas F; Hillman, Robert E

    2011-02-01

    In prior work, a manually derived measure of vocal fold vibratory phase asymmetry correlated to varying degrees with visual judgments made from laryngeal high-speed videoendoscopy (HSV) recordings. This investigation extended this work by establishing an automated HSV-based framework to quantify 3 categories of vocal fold vibratory asymmetry. HSV-based analysis provided for cycle-to-cycle estimates of left-right phase asymmetry, left-right amplitude asymmetry, and axis shift during glottal closure for 52 speakers with no vocal pathology producing comfortable and pressed phonation. An initial cross-validation of the automated left-right phase asymmetry measure was performed by correlating the measure with other objective and subjective assessments of phase asymmetry. Vocal fold vibratory asymmetry was exhibited to a similar extent in both comfortable and pressed phonations. The automated measure of left-right phase asymmetry strongly correlated with manually derived measures and moderately correlated with visual-perceptual ratings. Correlations with the visual-perceptual ratings remained relatively consistent as the automated measure was derived from kymograms taken at different glottal locations. An automated HSV-based framework for the quantification of vocal fold vibratory asymmetry was developed and initially validated. This framework serves as a platform for investigating relationships between vocal fold tissue motion and acoustic measures of voice function.

  9. Detection of passive movement of the arytenoid cartilage in unilateral vocal-fold paralysis by laryngoscopic observation: useful diagnostic findings.

    PubMed

    Okamoto, Isaku; Tokashiki, Ryoji; Hiramatsu, Hiroyuki; Motohashi, Ray; Suzuki, Mamoru

    2012-02-01

    In a previous study of patients with unilateral vocal-fold paralysis (UVFP), three-dimensional computed tomography (3DCT) revealed passive movement during phonation, with the arytenoid cartilage on the paralyzed side pushed to the unaffected side and deviated upwards. The present work compares the 3DCT findings with those obtained by 2-dimensional endoscopy to visualize the vertical passive movement of the arytenoid cartilage. The study population consisted of 23 patients with UVFP and two with laryngeal deviation but normal movement of the vocal folds. Two endoscopic findings represented cranial deviation during phonation: posterior deviation of the arytenoid hump and lateral deviation of the muscular process. These two findings were classified into four grades, ranging from 0 (normal) to 3 (severe). Cranial displacement detected by 3DCT was also classified into four grades. Significant correlations were found between the 3DCT-determined grade of cranial displacement of the arytenoid cartilage and the grade assigned based on the two endoscopic findings. Moreover, lateral deviation of the muscular process was more significantly correlated with 3DCT grade than with endoscopic grade. Thus, endoscopic findings may be useful in the diagnosis of vocal-fold paralysis, and passive lateral deviation of the muscular process as an indicator of UVFP.

  10. Robust fundamental frequency estimation in sustained vowels: Detailed algorithmic comparisons and information fusion with adaptive Kalman filtering

    PubMed Central

    Tsanas, Athanasios; Zañartu, Matías; Little, Max A.; Fox, Cynthia; Ramig, Lorraine O.; Clifford, Gari D.

    2014-01-01

    There has been consistent interest among speech signal processing researchers in the accurate estimation of the fundamental frequency (F0) of speech signals. This study examines ten F0 estimation algorithms (some well-established and some proposed more recently) to determine which of these algorithms is, on average, better able to estimate F0 in the sustained vowel /a/. Moreover, a robust method for adaptively weighting the estimates of individual F0 estimation algorithms based on quality and performance measures is proposed, using an adaptive Kalman filter (KF) framework. The accuracy of the algorithms is validated using (a) a database of 117 synthetic realistic phonations obtained using a sophisticated physiological model of speech production and (b) a database of 65 recordings of human phonations where the glottal cycles are calculated from electroglottograph signals. On average, the sawtooth waveform inspired pitch estimator and the nearly defect-free algorithms provided the best individual F0 estimates, and the proposed KF approach resulted in a ∼16% improvement in accuracy over the best single F0 estimation algorithm. These findings may be useful in speech signal processing applications where sustained vowels are used to assess vocal quality, when very accurate F0 estimation is required. PMID:24815269

  11. Acoustic changes in student actors' voices after 12 months of training.

    PubMed

    Walzak, Peta; McCabe, Patricia; Madill, Cate; Sheard, Christine

    2008-05-01

    This study was to evaluate acoustic changes in student actors' voices after 12 months of actor training. The design used was a longitudinal study. Eighteen students enrolled in an Australian tertiary 3-year acting program (nine male and nine female) were assessed at the beginning of their acting course and again 12 months later using a questionnaire, interview, maximum phonation time (MPT), reading, spontaneous speaking, sustained phonation tasks, and a pitch range task. Samples were analyzed for MPT, fundamental frequency across tasks, pitch range for speaking and reading, singing pitch range, noise-to-harmonic ratio, shimmer, and jitter. After training, measures of shimmer significantly increased for both male and female participants. Female participants' pitch range significantly increased after training, with a significantly lower mean frequency for their lowest pitch. The finding of limited or negative changes for some measures indicate that further investigation is required into the long-term effects of actor voice training and which parameters of voicing are most targeted and valued in training. Particular investigation into the relationship between training targets and outcomes could more reliably inform acting programs about changes in teaching methodologies. Further research into the relationship between specific training techniques, physiological changes, and vocal changes may also provide information on implementing more evidence-based training methods.

  12. An investigation of the effects of a speech-restructuring treatment for stuttering on the distribution of intervals of phonation.

    PubMed

    Brown, Lisa; Wilson, Linda; Packman, Ann; Halaki, Mark; Onslow, Mark; Menzies, Ross

    2016-12-01

    The purpose of this study was to investigate whether stuttering reductions following the instatement phase of a speech-restructuring treatment for adults were accompanied by reductions in the frequency of short intervals of phonation (PIs). The study was prompted by the possibility that reductions in the frequency of short PIs is the mechanism underlying such reductions in stuttering. The distribution of PIs was determined for seven adults who stutter, before and immediately after the intensive phase of a speech-restructuring treatment program. Audiovisual recordings of conversational speech were made on both assessment occasions, with PIs recorded with an accelerometer. All seven participants had much lower levels of stuttering after treatment but these were associated with reductions in the frequency of short PIs for only four of them. For the other three participants, two showed no change in frequency of short PIs, while for the other participant the frequency of short PIs actually increased. Stuttering reduction with speech-restructuring treatment can co-occur with reduction in the frequency of short PIs. However, the latter does not appear necessary for this reduction in stuttering to occur. Thus, speech-restructuring treatment must have other, or additional, treatment agents for stuttering to reduce. Copyright © 2016 Elsevier Inc. All rights reserved.

  13. Evaluation of Phonatory Behavior and Voice Quality in Patients with Multiple Sclerosis Treated with Deep Brain Stimulation.

    PubMed

    Pützer, Manfred; Wokurek, Wolfgang; Moringlane, Jean Richard

    2017-07-01

    The effect of deep brain stimulation (DBS) on phonatory behavior and voice quality in eight patients with multiple sclerosis (MS) was examined instrumentally and perceptually. The acoustic signals of vowel productions obtained from patients (produced with and without stimulation) and from a group of 16 healthy control speakers were analyzed to prove statistically the changes of phonatory behavior and voice quality. This is a randomized study. Firstly, a new parametrization was used to determine phonatory behavior. Secondly, a perceptual evaluation of voice quality of the same speech material was performed. With stimulation, phonation has a greater tendency to be strained. The results of perceptual evaluation support this strained phonation behavior under stimulation, resulting in a smaller degree of breathiness ratings of all raters. Without stimulation, an impaired and partly disturbed adduction of the vocal folds can be shown. These findings are also supported in the perceptual experiment providing a higher degree of hoarseness ratings of all raters for these signals. High-frequency electrical impulses to the thalamus in patients with MS influence the phonatory behavior of their vocal folds. The results suggest the need for long-term monitoring of phonatory behavior during DBS to initiate adequate treatments without delay. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  14. Age-Related Differences of Maximum Phonation Time in Patients after Cardiac Surgery

    PubMed Central

    Kasahara, Yusuke; Hiraki, Koji; Hirano, Yasuyuki; Watanabe, Satoshi

    2017-01-01

    Background and aims: Maximum phonation time (MPT), which is related to respiratory function, is widely used to evaluate maximum vocal capabilities, because its use is non-invasive, quick, and inexpensive. We aimed to examine differences in MPT by age, following recovery phase II cardiac rehabilitation (CR). Methods: This longitudinal observational study assessed 50 consecutive cardiac patients who were divided into the middle-aged group (<65 years, n = 29) and older-aged group (≥65 years, n = 21). MPTs were measured at 1 and 3 months after cardiac surgery, and were compared. Results: The duration of MPT increased more significantly from month 1 to month 3 in the middle-aged group (19.2 ± 7.8 to 27.1 ± 11.6 s, p < 0.001) than in the older-aged group (12.6 ± 3.5 to 17.9 ± 6.0 s, p < 0.001). However, no statistically significant difference occurred in the % change of MPT from 1 month to 3 months after cardiac surgery between the middle-aged group and older-aged group, respectively (41.1% vs. 42.1%). In addition, there were no significant interactions of MPT in the two groups for 1 versus 3 months (F = 1.65, p = 0.20). Conclusion: Following phase II, CR improved MPT for all cardiac surgery patients. PMID:29267218

  15. Age-Related Differences of Maximum Phonation Time in Patients after Cardiac Surgery.

    PubMed

    Izawa, Kazuhiro P; Kasahara, Yusuke; Hiraki, Koji; Hirano, Yasuyuki; Watanabe, Satoshi

    2017-12-21

    Background and aims: Maximum phonation time (MPT), which is related to respiratory function, is widely used to evaluate maximum vocal capabilities, because its use is non-invasive, quick, and inexpensive. We aimed to examine differences in MPT by age, following recovery phase II cardiac rehabilitation (CR). Methods: This longitudinal observational study assessed 50 consecutive cardiac patients who were divided into the middle-aged group (<65 years, n = 29) and older-aged group (≥65 years, n = 21). MPTs were measured at 1 and 3 months after cardiac surgery, and were compared. Results: The duration of MPT increased more significantly from month 1 to month 3 in the middle-aged group (19.2 ± 7.8 to 27.1 ± 11.6 s, p < 0.001) than in the older-aged group (12.6 ± 3.5 to 17.9 ± 6.0 s, p < 0.001). However, no statistically significant difference occurred in the % change of MPT from 1 month to 3 months after cardiac surgery between the middle-aged group and older-aged group, respectively (41.1% vs. 42.1%). In addition, there were no significant interactions of MPT in the two groups for 1 versus 3 months (F = 1.65, p = 0.20). Conclusion: Following phase II, CR improved MPT for all cardiac surgery patients.

  16. Expression and distribution of hyaluronic acid and CD44 in unphonated human vocal fold mucosa.

    PubMed

    Sato, Kiminori; Umeno, Hirohito; Nakashima, Tadashi; Nonaka, Satoshi; Harabuchi, Yasuaki

    2009-11-01

    The tension caused by phonation (vocal fold vibration) is hypothesized to stimulate vocal fold stellate cells (VFSCs) in the maculae flavae (MFe) to accelerate production of extracellular matrices. The distribution of hyaluronic acid (HA) and expression of CD44 (a cell surface receptor for HA) were examined in human vocal fold mucosae (VFMe) that had remained unphonated since birth. Five specimens of VFMe (3 adults, 2 children) that had remained unphonated since birth were investigated with Alcian blue staining, hyaluronidase digestion, and immunohistochemistry for CD44. The VFMe containing MFe were hypoplastic and rudimentary. The VFMe did not have a vocal ligament, Reinke's space, or a layered structure, and the lamina propria appeared as a uniform structure. In the children, HA was distributed in the VFMe containing MFe. In the adults, HA had decreased in the VFMe containing MFe. In both groups, the VFSCs in the MFe and the fibroblasts in the lamina propria expressed little CD44. This study supports the hypothesis that the tensions caused by vocal fold vibration stimulate the VFSCs in the MFe to accelerate production of extracellular matrices and form the layered structure. Phonation after birth is one of the important factors in the growth and development of the human VFMe.

  17. Histopathologic investigations of the unphonated human child vocal fold mucosa.

    PubMed

    Sato, Kiminori; Umeno, Hirohito; Nakashima, Tadashi; Nonaka, Satoshi; Harabuchi, Yasuaki

    2012-01-01

    Vocal fold stellate cells (VFSCs) in the maculae flavae (MFe) located at both ends of the vocal fold mucosa are inferred to be involved in the metabolism of extracellular matrices. MFe are also considered to be an important structure in the growth and development of the human vocal fold mucosa. Tension caused by phonation (vocal fold vibration) is hypothesized to stimulate VFSCs to accelerate production of extracellular matrices. Human child vocal fold mucosae unphonated since birth were investigated histologically. Histologic analysis of human child vocal fold mucosa. Vocal fold mucosae, which have remained unphonated since birth, of two children (7 and 12 years old) with cerebral palsy were investigated by light and electron microscopy and compared with normal subjects. Vocal fold mucosae and MFe were hypoplastic and rudimentary and did not have a vocal ligament, Reinke's space, or the layered structure. The lamina propria appeared as a uniform structure. Some VFSCs in the MFe showed degeneration and not many vesicles were present at the periphery of the cytoplasm. The VFSCs synthesized fewer extracellular matrices, such as fibrous protein and glycosaminoglycan. The VFSCs appeared to have decreased activity. Vocal fold vibration (phonation) after birth is an important factor in the growth and development of the human vocal fold mucosa. Copyright © 2012 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  18. Value of Laryngeal Electromyography in Spasmodic Dysphonia Diagnosis and Therapy.

    PubMed

    Yang, Qingwen; Xu, Wen; Li, Yun; Cheng, Liyu

    2015-07-01

    To investigate the role of laryngeal electromyography (LEMG) in the diagnosis and treatment of spasmodic dysphonia (SD). The clinical manifestations, characteristics of motor unit potentials (MUPs), recruitment potentials, and laryngeal nerve evoked potentials (EPs) in LEMG, as well as the changes after botulinum toxin (BTX) treatment, were analyzed in 39 patients with adductor SD. The main clinical manifestations were a strained voice and phonation interruptions; in addition, the patients displayed hyper-adducted vocal folds during phonation. LEMG revealed significantly increased amplitudes of the thyroarytenoid muscle MUPs. The recruitment potentials were in a dense bunch, discharging full interference patterns with significantly increased amplitudes; the mean and maximum amplitude of recruitment potentials were 3090 μV and 5000 μV, respectively. The amplitude of EPs of thyroarytenoid muscle increased significantly; the mean and maximum amplitudes were 10.3 mV and 26.3 mV, respectively. After BTX was injected, the LEMG revealed denervation changes, and the EPs weakened or disappeared in the injected muscle. SD could be diagnosed, and the therapeutic efficacy of SD treatments could be evaluated based on clinical characteristics combined with LEMG characteristics. The increased amplitudes of the recruitment potentials and EPs of the thyroarytenoid muscle were the characteristic indexes. After BTX was injected, denervated potential characteristics appeared in the muscles. © The Author(s) 2015.

  19. Adhesion of a monolayer of fibroblast cells to fibronectin under sonic vibrations in a bioreactor.

    PubMed

    Titze, Ingo R; Klemuk, Sarah A; Lu, Xiaoying

    2012-06-01

    We examined cell adhesion to a surface under vibrational forces approximating those of phonation. A monolayer of human fibroblast cells was seeded on a fibronectin-coated glass coverslip, which was attached to either the rotating part or the stationary part of a rheometer-bioreactor. The temperature, humidity, carbon dioxide level, nutrients, and cell seeding density were controlled. The cell density was on the order of 1,000 to 5,000 cells per square millimeter. Target stresses above 1 kPa at an oscillatory frequency of 100 Hz were chosen to reflect conditions of vocal fold tissue vibration. Fibronectin coating provided enough adhesion to support at least 2 kPa of oscillating stress, but only about 0.1 kPa of steady rotational shear. For stresses exceeding those limits, the cells were not able to adhere to the thin film of fibronectin. Cells will adhere to a planar surface under stresses typical of phonation, which provide a more stringent test than adherence in a 3-dimensional matrix. The density of cell seeding on the coverslip played a role in cell-extracellular matrix adhesion, in that the cells adhered to each other more than to the fibronectin coating when the cells were nearly confluent.

  20. Uncertainties on the definition of critical rainfall patterns for debris-flows triggering. Results from the Rebaixader monitoring site (Central Pyrenees)

    NASA Astrophysics Data System (ADS)

    Hürlimann, Marcel; Abancó, Clàudia; Moya, Jose; Berenguer, Marc

    2015-04-01

    Empirical rainfall thresholds are a widespread technique in debris-flow hazard assessment and can be established by statistical analysis of historic data. Typically, data from one or several rain gauges located nearby the affected catchment is used to define the triggering conditions. However, this procedure has been demonstrated not to be accurate enough due to the spatial variability of convective rainstorms. In 2009, a monitoring system was installed in the Rebaixader catchment, Central Pyrenees (Spain). Since then, 28 torrential flows (debris flows and debris floods) have occurred and rainfall data of 25 of them are available with a 5-minutes frequency of recording ("event rainfalls"). Other 142 rainfalls that did not trigger events ("no event rainfalls) were also collected and analysed. The goal of this work was threefold: a) characterize rainfall episodes in the Rebaixader catchment and compare rainfall data that triggered torrential events and others that did not; b) define and test Intensity-Duration (ID) thresholds using rainfall data measured inside the catchment; c) estimate the uncertainty derived from the use of rain gauges located outside the catchment based on the spatial correlation depicted by radar rainfall maps. The results of the statistical analysis showed that the parameters that more distinguish between the two populations of rainfalls are the rainfall intensities, the mean rainfall and the total precipitation. On the other side, the storm duration and the antecedent rainfall are not significantly different between "event rainfalls" and "no event rainfalls". Four different ID rainfall thresholds were derived based on the dataset of the first 5 years and tested using the 2014 dataset. The results of the test indicated that the threshold corresponding to the 90% percentile showed the best performance. Weather radar data was used to analyse the spatial variability of the triggering rainfalls. The analysis indicates that rain gauges outside the catchment may be considered useful or not to describe the rainfall depending on the type of rainfall. For widespread rainfalls, further rain gauges can give a reliable measurement, because the spatial correlation decreases slowly with the distance between the rain gauge and the debris-flow initiation area. Contrarily, local storm cells show higher space-time variability and, therefore, representative rainfall measurements are obtained only by the closest rain gauges. In conclusion, the definition of rainfall thresholds is a delicate task. When the rainfall records are coming from gauges that are outside the catchment under consideration, the data should be carefully analysed and crosschecked with radar data (especially for small convective cells).

  1. Significance of flow clustering and sequencing on sediment transport: 1D sediment transport modelling

    NASA Astrophysics Data System (ADS)

    Hassan, Kazi; Allen, Deonie; Haynes, Heather

    2016-04-01

    This paper considers 1D hydraulic model data on the effect of high flow clusters and sequencing on sediment transport. Using observed flow gauge data from the River Caldew, England, a novel stochastic modelling approach was developed in order to create alternative 50 year flow sequences. Whilst the observed probability density of gauge data was preserved in all sequences, the order in which those flows occurred was varied using the output from a Hidden Markov Model (HMM) with generalised Pareto distribution (GP). In total, one hundred 50 year synthetic flow series were generated and used as the inflow boundary conditions for individual flow series model runs using the 1D sediment transport model HEC-RAS. The model routed graded sediment through the case study river reach to define the long-term morphological changes. Comparison of individual simulations provided a detailed understanding of the sensitivity of channel capacity to flow sequence. Specifically, each 50 year synthetic flow sequence was analysed using a 3-month, 6-month or 12-month rolling window approach and classified for clusters in peak discharge. As a cluster is described as a temporal grouping of flow events above a specified threshold, the threshold condition used herein is considered as a morphologically active channel forming discharge event. Thus, clusters were identified for peak discharges in excess of 10%, 20%, 50%, 100% and 150% of the 1 year Return Period (RP) event. The window of above-peak flows also required cluster definition and was tested for timeframes 1, 2, 10 and 30 days. Subsequently, clusters could be described in terms of the number of events, maximum peak flow discharge, cumulative flow discharge and skewness (i.e. a description of the flow sequence). The model output for each cluster was analysed for the cumulative flow volume and cumulative sediment transport (mass). This was then compared to the total sediment transport of a single flow event of equivalent flow volume. Results illustrate that clustered flood events generated sediment loads up to an order of magnitude greater than that of individual events of the same flood volume. Correlations were significant for sediment volume compared to both maximum flow discharge (R2<0.8) and number of events (R2 -0.5 to -0.7) within the cluster. The strongest correlations occurred for clusters with a greater number of flow events only slightly above-threshold. This illustrates that the numerical model can capture a degree of the non-linear morphological response to flow magnitude. Analysis of the relationship between morphological change and the skewness of flow events within each cluster was also determined, illustrating only minor sensitivity to cluster peak distribution skewness. This is surprising and discussion is presented on model limitations, including the capability of sediment transport formulae to effectively account for temporal processes of antecedent flow, hysteresis, local supply etc.

  2. Invited perspectives: Hydrological perspectives on precipitation intensity-duration thresholds for landslide initiation: proposing hydro-meteorological thresholds

    NASA Astrophysics Data System (ADS)

    Bogaard, Thom; Greco, Roberto

    2018-01-01

    Many shallow landslides and debris flows are precipitation initiated. Therefore, regional landslide hazard assessment is often based on empirically derived precipitation intensity-duration (ID) thresholds and landslide inventories. Generally, two features of precipitation events are plotted and labeled with (shallow) landslide occurrence or non-occurrence. Hereafter, a separation line or zone is drawn, mostly in logarithmic space. The practical background of ID is that often only meteorological information is available when analyzing (non-)occurrence of shallow landslides and, at the same time, it could be that precipitation information is a good proxy for both meteorological trigger and hydrological cause. Although applied in many case studies, this approach suffers from many false positives as well as limited physical process understanding. Some first steps towards a more hydrologically based approach have been proposed in the past, but these efforts received limited follow-up.Therefore, the objective of our paper is to (a) critically analyze the concept of precipitation ID thresholds for shallow landslides and debris flows from a hydro-meteorological point of view and (b) propose a trigger-cause conceptual framework for lumped regional hydro-meteorological hazard assessment based on published examples and associated discussion. We discuss the ID thresholds in relation to return periods of precipitation, soil physics, and slope and catchment water balance. With this paper, we aim to contribute to the development of a stronger conceptual model for regional landslide hazard assessment based on physical process understanding and empirical data.

  3. Synthetic Jets in Cross-flow. Part 1; Round Jet

    NASA Technical Reports Server (NTRS)

    Zaman, K. B. M. Q.; Milanovic, Ivana M.

    2003-01-01

    Results of an experimental investigation on synthetic jets from round orifices with and without cross-flow are presented. Jet Reynolds number up to 46,000 with a fully turbulent approach boundary layer, and Stokes number up to 400. are covered. The threshold of stroke length for synthetic jet formation. in the absence of the cross-flow, is found to be Lo /D approximately 0.5. Above Lo /D is approximately 10, the profiles of normalized centerline mean velocity appear to become invariant. It is reasoned that the latter threshold may be related to the phenomenon of saturation of impulsively generated vortices. In the presence of the cross-flow, the penetration height of a synthetic jet is found to depend on the momentum- flux ratio . When this ratio is defined in terms of the maximum jet velocity and the cross-flow velocity. not only all data collapse but also the jet trajectory is predicted well by correlation equation available for steady jets-in-cross-flow. Distributions of mean velocity, streamwise vorticity as well as turbulence intensity for a synthetic jet in cross-flow are found to be similar to those of a steady jet-in-cross-flow. A pair of counter-rotating streamwise vortices, corresponding to the bound vortex pair of the steady case, is clearly observed. Mean velocity distribution exhibits a dome of low momentum fluid pulled up from the boundary layer, and the entire domain is characterized by high turbulence.

  4. Value of a dual-polarized gap-filling radar in support of southern California post-fire debris-flow warnings

    USGS Publications Warehouse

    Jorgensen, David P.; Hanshaw, Maiana N.; Schmidt, Kevin M.; Laber, Jayme L; Staley, Dennis M.; Kean, Jason W.; Restrepo, Pedro J.

    2011-01-01

    A portable truck-mounted C-band Doppler weather radar was deployed to observe rainfall over the Station Fire burn area near Los Angeles, California, during the winter of 2009/10 to assist with debris-flow warning decisions. The deployments were a component of a joint NOAA–U.S. Geological Survey (USGS) research effort to improve definition of the rainfall conditions that trigger debris flows from steep topography within recent wildfire burn areas. A procedure was implemented to blend various dual-polarized estimators of precipitation (for radar observations taken below the freezing level) using threshold values for differential reflectivity and specific differential phase shift that improves the accuracy of the rainfall estimates over a specific burn area sited with terrestrial tipping-bucket rain gauges. The portable radar outperformed local Weather Surveillance Radar-1988 Doppler (WSR-88D) National Weather Service network radars in detecting rainfall capable of initiating post-fire runoff-generated debris flows. The network radars underestimated hourly precipitation totals by about 50%. Consistent with intensity–duration threshold curves determined from past debris-flow events in burned areas in Southern California, the portable radar-derived rainfall rates exceeded the empirical thresholds over a wider range of storm durations with a higher spatial resolution than local National Weather Service operational radars. Moreover, the truck-mounted C-band radar dual-polarimetric-derived estimates of rainfall intensity provided a better guide to the expected severity of debris-flow events, based on criteria derived from previous events using rain gauge data, than traditional radar-derived rainfall approaches using reflectivity–rainfall relationships for either the portable or operational network WSR-88D radars. Part of the reason for the improvement was due to siting the radar closer to the burn zone than the WSR-88Ds, but use of the dual-polarimetric variables improved the rainfall estimation by ~12% over the use of traditional Z–R relationships.

  5. The effect of hypnosis on pain and peripheral blood flow in sickle-cell disease: a pilot study

    PubMed Central

    Bhatt, Ravi R; Martin, Sarah R; Evans, Subhadra; Lung, Kirsten; Coates, Thomas D; Zeltzer, Lonnie K; Tsao, Jennie C

    2017-01-01

    Background Vaso-occlusive pain crises (VOCs) are the “hallmark” of sickle-cell disease (SCD) and can lead to sympathetic nervous system dysfunction. Increased sympathetic nervous system activation during VOCs and/or pain can result in vasoconstriction, which may increase the risk for subsequent VOCs and pain. Hypnosis is a neuromodulatory intervention that may attenuate vascular and pain responsiveness. Due to the lack of laboratory-controlled pain studies in patients with SCD and healthy controls, the specific effects of hypnosis on acute pain-associated vascular responses are unknown. The current study assessed the effects of hypnosis on peripheral blood flow, pain threshold, tolerance, and intensity in adults with and without SCD. Subjects and methods Fourteen patients with SCD and 14 healthy controls were included. Participants underwent three laboratory pain tasks before and during a 30-minute hypnosis session. Peripheral blood flow, pain threshold, tolerance, and intensity before and during hypnosis were examined. Results A single 30-minute hypnosis session decreased pain intensity by a moderate amount in patients with SCD. Pain threshold and tolerance increased following hypnosis in the control group, but not in patients with SCD. Patients with SCD exhibited lower baseline peripheral blood flow and a greater increase in blood flow following hypnosis than controls. Conclusion Given that peripheral vasoconstriction plays a role in the development of VOC, current findings provide support for further laboratory and clinical investigations of the effects of cognitive–behavioral neuromodulatory interventions on pain responses and peripheral vascular flow in patients with SCD. Current results suggest that hypnosis may increase peripheral vasodilation during both the anticipation and experience of pain in patients with SCD. These findings indicate a need for further examination of the effects of hypnosis on pain and vascular responses utilizing a randomized controlled trial design. Further evidence may help determine unique effects of hypnosis and potential benefits of integrating cognitive–behavioral neuromodulatory interventions into SCD treatment. PMID:28769584

  6. Quivering on the brink: Common observations of turbidity current frequency and triggering in disparate settings

    NASA Astrophysics Data System (ADS)

    Clare, M. A.; Rosenberger, K. J.; Parsons, D. R.; Gales, J. A.; Gwiazda, R.; Paull, C. K.; Talling, P.; Cartigny, M.; Azpiroz, M.; Pope, E.; Hizzett, J. L.; Hughes Clarke, J. E.

    2017-12-01

    Turbidity currents pose a hazard to seafloor infrastructure, convey sediment to the deep sea, and provide nutrients to benthic communities. Despite their importance, we still know little about specifically how and when such powerful long run-out flows are triggered, and how strongly different trigger mechanisms control flow behaviour. New advances in direct monitoring now allow us to precisely constrain turbidity current frequency and test the efficiency of previously hypothesised triggering mechanisms. Here, we document the timing of sub-annual turbidity currents based on direct measurements using Acoustic Doppler Current Profilers at four different sites. Two sites are located at offshore fjord-head deltas in British Columbia (Squamish delta & Bute Inlet), which are fed by meltwater in spring and summer. The third is the deep-water Congo Canyon, which is located offshore Angola, and is fed by the second largest river in the world. Fourth is the Monterey Canyon, offshore California, which does not have a direct link to a river and is instead fed by littoral drift. Despite the differences in scale and setting, all of the sites show similar trends in turbidity current frequency. The first commonality is that flow timing is typically delayed (hours to weeks) following periods of rapid sediment discharge, rather than immediately coincident with them. The second commonality is that flows are rare (typically they do not occur at all) for at least half of the year in each of the sites. Instead, flows are clustered within a specific time window. We underline the importance of preconditioning prior to, and during that time window and propose that an environmental threshold must be exceeded in order to "switch on" these systems. This threshold primarily relates to magnitude of sediment delivery at the head of the channel or canyon. Once that threshold is surpassed, then systems are primed for action, quivering on the brink, allowing even small external perturbations to trigger flows.

  7. The cerebrovascular response to carbon dioxide in humans

    PubMed Central

    Battisti-Charbonney, A; Fisher, J; Duffin, J

    2011-01-01

    Abstract Carbon dioxide (CO2) increases cerebral blood flow and arterial blood pressure. Cerebral blood flow increases not only due to the vasodilating effect of CO2 but also because of the increased perfusion pressure after autoregulation is exhausted. Our objective was to measure the responses of both middle cerebral artery velocity (MCAv) and mean arterial blood pressure (MAP) to CO2 in human subjects using Duffin-type isoxic rebreathing tests. Comparisons of isoxic hyperoxic with isoxic hypoxic tests enabled the effect of oxygen tension to be determined. During rebreathing the MCAv response to CO2 was sigmoidal below a discernible threshold CO2 tension, increasing from a hypocapnic minimum to a hypercapnic maximum. In most subjects this threshold corresponded with the CO2 tension at which MAP began to increase. Above this threshold both MCAv and MAP increased linearly with CO2 tension. The sigmoidal MCAv response was centred at a CO2 tension close to normal resting values (overall mean 36 mmHg). While hypoxia increased the hypercapnic maximum percentage increase in MCAv with CO2 (overall means from 76.5 to 108%) it did not affect other sigmoid parameters. Hypoxia also did not alter the supra-threshold MCAv and MAP responses to CO2 (overall mean slopes 5.5% mmHg-1 and 2.1 mmHg mmHg−1, respectively), but did reduce the threshold (overall means from 51.5 to 46.8 mmHg). We concluded that in the MCAv response range below the threshold for the increase of MAP with CO2, the MCAv measurement reflects vascular reactivity to CO2 alone at a constant MAP. PMID:21521758

  8. Mechanisms of breathing instability in patients with obstructive sleep apnea.

    PubMed

    Younes, Magdy; Ostrowski, Michele; Atkar, Raj; Laprairie, John; Siemens, Andrea; Hanly, Patrick

    2007-12-01

    The response to chemical stimuli (chemical responsiveness) and the increases in respiratory drive required for arousal (arousal threshold) and for opening the airway without arousal (effective recruitment threshold) are important determinants of ventilatory instability and, hence, severity of obstructive apnea. We measured these variables in 21 obstructive apnea patients (apnea-hypopnea index 91 +/- 24 h(-1)) while on continuous-positive-airway pressure. During sleep, pressure was intermittently reduced (dial down) to induce severe hypopneas. Dial downs were done on room air and following approximately 30 s of breathing hypercapneic and/or hypoxic mixtures, which induced a range of ventilatory stimulation before dial down. Ventilation just before dial down and flow during dial down were measured. Chemical responsiveness, estimated as the percent increase in ventilation during the 5(th) breath following administration of 6% CO(2) combined with approximately 4% desaturation, was large (187 +/- 117%). Arousal threshold, estimated as the percent increase in ventilation associated with a 50% probability of arousal, ranged from 40% to >268% and was <120% in 12/21 patients, indicating that in many patients arousal occurs with modest changes in chemical drive. Effective recruitment threshold, estimated as percent increase in pre-dial-down ventilation associated with a significant increase in dial-down flow, ranged from zero to >174% and was <110% in 12/21 patients, indicating that in many patients reflex dilatation occurs with modest increases in drive. The two thresholds were not correlated. In most OSA patients, airway patency may be maintained with only modest increases in chemical drive, but instability results because of a low arousal threshold and a brisk increase in drive following brief reduction in alveolar ventilation.

  9. The singing/acting mature adult--singing instruction perspective.

    PubMed

    Westerman Gregg, J

    1997-06-01

    Complete knowledge of anatomy and physiology of the vocal mechanism and tract is essential for the voice teacher to be maximally effective. Possible contributing factors to vocal attrition in the mature singer/actor are outlined: poor posture, inadequate respiratory function, lack of adequate hydration, phonatory hyperfunction, habitual speaking pitch at too low a frequency, lack of resonance, tongue tension affecting phonation, resonation, and articulation. Techniques for rehabilitation of the damaged voice are recommended.

  10. Effect of Load Carriage on Upper Limb Performance.

    PubMed

    Hadid, Amir; Katz, Inbar; Haker, Tal; Zeilig, Gabi; Defrin, Ruth; Epstein, Yoram; Gefen, Amit

    2017-05-01

    Carrying heavy backpacks are often associated with shoulder discomfort or pain, loss of sensorimotor functions, and brachial plexus injuries that might hamper performance. On the basis of previous research, the cause of these symptoms could be tissue deformations of the brachial plexus and the subclavian artery caused by the shoulder straps. This study aimed to evaluate the changes in the upper extremity hemodynamic and neural function and to assess how they are associated with brachial plexus tissue deformation during heavy load carriage. Ten young healthy adults carried for 45 min a backpack load (40% of their body weight) while standing freely, followed by 15 min of recovery (unloaded). Index-finger microvascular flow and sensorimotor function were measured before and after carrying the load, and after recovery. The following sensorimotor functions were measured: light touch thresholds by the index finger and little finger, forearm thermal sensation thresholds, and gross motor function. In addition, marksmanship accuracy, as an indication for fine motor function, was tested. Load carriage resulted in an average decrease of ~40% in microvascular flow and a significant decrement in light touch sensation (P < 0.05), but not in thermal sensation and gross motor functions. An increase in the light touch threshold was highly correlated with a reduced index-finger microvascular blood flow (r = 0.79, P = 0.007). These physiological effects were associated with a functional 34% decrement in the accuracy of target acquisition. Heavy load carriage resulted in impaired light touch sensitivity and fine motor function, which were associated with reduced finger microvascular blood flow.

  11. Stress-strain analysis of contractility in the ileum in response to flow and ramp distension in streptozotocin-induced diabetic rats--association with advanced glycation end product formation.

    PubMed

    Zhao, Jingbo; Chen, Pengmin; Gregersen, Hans

    2015-04-13

    This study compared the ileal contractility and analyzed the association between contractility with advanced glycation end product (AGE) formation in normal and streptozotocin (STZ)-induced diabetic rats. Nine STZ-induced diabetic rats (Diabetes group) and 9 normal rats (Normal group) were used. The motility experiments were carried out on ileums in organ baths containing physiological Krebs solution. Ileal pressure and diameter changes were obtained from basic, flow-induced and ramp distension-induced contractions. The frequency and amplitude of contractions were analyzed from pressure-diameter curves. Distension-induced contraction thresholds and maximum contraction amplitude of basic and flow-induced contractions were calculated in terms of stress and strain. AGE and its receptor (RAGE) in the layers were detected by immunohistochemistry staining. The maximum stress of flow-induced contractions was lowest in the Diabetes Group (P<0.05). During ramp distension, the pressure and stress thresholds and Young's modulus to induce phasic contraction were lowest in the Diabetes Group (P<0.05 and P<0.01). AGE and RAGE expressions in the different ileum layers were highest in the Diabetes group. The contraction pressure and stress thresholds were significantly associated with AGE expression in the muscle layer and RAGE expression in mucosa epithelium and neurons. The diabetic intestine was hypersensitive to distension for contraction induction. However, the contraction force produced by smooth muscle was lowest in diabetic rats. Increased AGE/RAGE expression was associated with the contractility changes in diabetic rats. Copyright © 2015 Elsevier Ltd. All rights reserved.

  12. A probabilistic approach to quantifying hydrologic thresholds regulating migration of adult Atlantic salmon into spawning streams

    NASA Astrophysics Data System (ADS)

    Lazzaro, G.; Soulsby, C.; Tetzlaff, D.; Botter, G.

    2017-03-01

    Atlantic salmon is an economically and ecologically important fish species, whose survival is dependent on successful spawning in headwater rivers. Streamflow dynamics often have a strong control on spawning because fish require sufficiently high discharges to move upriver and enter spawning streams. However, these streamflow effects are modulated by biological factors such as the number and the timing of returning fish in relation to the annual spawning window in the fall/winter. In this paper, we develop and apply a novel probabilistic approach to quantify these interactions using a parsimonious outflux-influx model linking the number of female salmon emigrating (i.e., outflux) and returning (i.e., influx) to a spawning stream in Scotland. The model explicitly accounts for the interannual variability of the hydrologic regime and the hydrological connectivity of spawning streams to main rivers. Model results are evaluated against a detailed long-term (40 years) hydroecological data set that includes annual fluxes of salmon, allowing us to explicitly assess the role of discharge variability. The satisfactory model results show quantitatively that hydrologic variability contributes to the observed dynamics of salmon returns, with a good correlation between the positive (negative) peaks in the immigration data set and the exceedance (nonexceedance) probability of a threshold flow (0.3 m3/s). Importantly, model performance deteriorates when the interannual variability of flow regime is disregarded. The analysis suggests that flow thresholds and hydrological connectivity for spawning return represent a quantifiable and predictable feature of salmon rivers, which may be helpful in decision making where flow regimes are altered by water abstractions.

  13. Determination of base-flow characteristics at selected streamflow-gaging stations on the Mad River, Ohio

    USGS Publications Warehouse

    Koltun, G.F.

    1995-01-01

    This report describes the results of a study to estimate characteristics of base flow and sustained ground-water discharge at five streamflow-gaging stations on the Mad River in Ohio. The five streamflow-gaging stations are located at Zanesfield, near Urbana, at St. Paris Pike (at Eagle City), near Springfield, and near Dayton. The median of the annual-mean base flows, determined by means of hydrograph separation, ranged from 0.64 (ft3/s)/mi2 (cubic feet per second per square mile) at Zanesfield to 0.74 (ft3/s)/mi2 at St. Paris Pike. The median percentage of annual total streamflow attributed to base flow ranged from 61.8 percent at Zanesfield to 76.1 percent near Urbana. Estimates of an upper limit (or threshold) at which base flows can be considered to be composed predominately of sustained ground-water discharge were made by constructing and analyzing base- flow-duration curves. The sustained ground-water discharges (base flows less than or equal to the estimated sustained ground-water-discharge thresholds) are assumed to originate from ground-water- flow systems that are minimally affected by seasonal climatic changes. The median sustained ground- water discharge ranged from 0.11 (ft3/s)/mi2 at Zanesfield to 0.26 (ft3/s)/mi2 at St. Paris Pike (at Eagle City) and near Springfield. The median sustained ground-water discharge, expressed as a percentage of the median annual-mean base flow, ranged from 17.2 percent at Zanesfield to 38.6 percent near Springfield.

  14. Noninvasive Thermal Evaluation of Ventriculoperitoneal Shunt Patency and Cerebrospinal Fluid Flow Using a Flow Enhancing Device.

    PubMed

    Hameed, Mustafa Q; Zurakowski, David; Proctor, Mark R; Stone, Scellig S D; Warf, Benjamin C; Smith, Edward R; Goumnerova, Liliana C; Swoboda, Marek; Anor, Tomer; Madsen, Joseph R

    2018-06-16

    While a noninvasive flow determination would be desirable in the diagnosis of cerebrospinal fluid shunt malfunction, existing studies have not yet defined a role for thermal flow detection. To evaluate a revised test protocol using a micropumper designed to transiently enhance flow during thermal testing to determine whether thermal detection of flow is associated with progression to shunt revision surgery. Eighty-two unique tests were performed in 71 shunts. The primary outcome, need for revision within 7 d of testing, was compared with results of micropumper-augmented thermal flow detection. Statistical analysis was based on blind interpretation of test results and raw temperature data recorded during testing. The test was sensitive (73%) and specific (68%) in predicting need for revision, with 5.6-fold higher probability of revision when flow was not detected. Negative predictive value in our sample was 94.2%. The probability of not requiring revision increased with increasing total temperature drop. Analysis of various possible thresholds showed that the optimal temperature cutoff may be lower than suggested by the manufacturer (0.125°C vs 0.2°C). This is the first study to report a strong association between thermal flow evaluation and a clinical impression that a shunt is not malfunctioning. The current recommended threshold may increase the false positive rate unnecessarily, and as clinicians gain experience with the method, they may find value in examining the temperature curves themselves. Multicenter studies are suggested to further define a role for this diagnostic test.

  15. Relationship between cavitation and loss of echogenicity from ultrasound contrast agents

    NASA Astrophysics Data System (ADS)

    Radhakrishnan, Kirthi; Bader, Kenneth B.; Haworth, Kevin J.; Kopechek, Jonathan A.; Raymond, Jason L.; Huang, Shao-Ling; McPherson, David D.; Holland, Christy K.

    2013-09-01

    Ultrasound contrast agents (UCAs) have the potential to nucleate cavitation and promote both beneficial and deleterious bioeffects in vivo. Previous studies have elucidated the pulse-duration-dependent pressure amplitude threshold for rapid loss of echogenicity due to UCA fragmentation. Previous studies have demonstrated that UCA fragmentation was concomitant with inertial cavitation. The purpose of this study was to evaluate the relationship between stable and inertial cavitation thresholds and loss of echogenicity of UCAs as a function of pulse duration. Determining the relationship between cavitation thresholds and loss of echogenicity of UCAs would enable monitoring of cavitation based upon the onscreen echogenicity in clinical applications. Two lipid-shelled UCAs, echogenic liposomes (ELIP) and Definity®, were insonified by a clinical ultrasound scanner in duplex spectral Doppler mode at four pulse durations (‘sample volumes’) in both a static system and a flow system. Cavitation emissions from the UCAs insonified by Doppler pulses were recorded using a passive cavitation detection system and stable and inertial cavitation thresholds ascertained. Loss of echogenicity from ELIP and Definity® was assessed within regions of interest on B-mode images. A numerical model based on UCA rupture predicted the functional form of the loss of echogenicity from ELIP and Definity®. Stable and inertial cavitation thresholds were found to have a weak dependence on pulse duration. Stable cavitation thresholds were lower than inertial cavitation thresholds. The power of cavitation emissions was an exponential function of the loss of echogenicity over the investigated range of acoustic pressures. Both ELIP and Definity® lost more than 80% echogenicity before the onset of stable or inertial cavitation. Once this level of echogenicity loss occurred, both stable and inertial cavitation were detected in the physiologic flow phantom. These results imply that stable and inertial cavitation are necessary in order to trigger complete loss of echogenicity acoustically from UCAs and this finding can be used when planning diagnostic and therapeutic applications.

  16. Relationship between cavitation and loss of echogenicity from ultrasound contrast agents

    PubMed Central

    Radhakrishnan, Kirthi; Bader, Kenneth B; Haworth, Kevin J; Kopechek, Jonathan A; Raymond, Jason L; Huang, Shao-Ling; McPherson, David D; Holland, Christy K

    2014-01-01

    Ultrasound contrast agents (UCAs) have the potential to nucleate cavitation and promote both beneficial and deleterious bioeffects in vivo. Previous studies have elucidated the pulse-duration dependent pressure amplitude threshold for rapid loss of echogenicity due to UCA fragmentation. Previous studies have demonstrated that UCA fragmentation was concomitant with inertial cavitation. The purpose of this study was to evaluate the relationship between stable and inertial cavitation thresholds and loss of echogenicity of UCAs as a function of pulse duration. Determining the relationship between cavitation thresholds and loss of echogenicity of UCAs would enable monitoring of cavitation based upon the on-screen echogenicity in clinical applications. Two lipid-shelled UCAs, echogenic liposomes (ELIP) and Definity®, were insonified by a clinical ultrasound scanner in duplex spectral Doppler mode at four pulse durations (“sample volumes”) in both a static system and a flow system. Cavitation emissions from the UCAs insonified by Doppler pulses were recorded using a passive cavitation detection system and stable and inertial cavitation thresholds ascertained. Loss of echogenicity from ELIP and Definity® was assessed within regions of interest on B-mode images. A numerical model based on UCA rupture predicted the functional form of the loss of echogenicity from ELIP and Definity®. Stable and inertial cavitation thresholds were found to have a weak dependence on pulse duration. Stable cavitation thresholds were lower than inertial cavitation thresholds. The power of cavitation emissions was an exponential function of the loss of echogenicity over the investigated range of acoustic pressures. Both ELIP and Definity® lost more than 80% echogenicity before the onset of stable or inertial cavitation. Once this level of echogenicity loss occurred, both stable and inertial cavitation were detected in the physiologic flow phantom. These results imply that stable and inertial cavitation are necessary in order to trigger complete loss of echogenicity acoustically from UCAs and this finding can be used when planning diagnostic and therapeutic applications. PMID:24002637

  17. Relationship between cavitation and loss of echogenicity from ultrasound contrast agents.

    PubMed

    Radhakrishnan, Kirthi; Bader, Kenneth B; Haworth, Kevin J; Kopechek, Jonathan A; Raymond, Jason L; Huang, Shao-Ling; McPherson, David D; Holland, Christy K

    2013-09-21

    Ultrasound contrast agents (UCAs) have the potential to nucleate cavitation and promote both beneficial and deleterious bioeffects in vivo. Previous studies have elucidated the pulse-duration-dependent pressure amplitude threshold for rapid loss of echogenicity due to UCA fragmentation. Previous studies have demonstrated that UCA fragmentation was concomitant with inertial cavitation. The purpose of this study was to evaluate the relationship between stable and inertial cavitation thresholds and loss of echogenicity of UCAs as a function of pulse duration. Determining the relationship between cavitation thresholds and loss of echogenicity of UCAs would enable monitoring of cavitation based upon the onscreen echogenicity in clinical applications. Two lipid-shelled UCAs, echogenic liposomes (ELIP) and Definity®, were insonified by a clinical ultrasound scanner in duplex spectral Doppler mode at four pulse durations ('sample volumes') in both a static system and a flow system. Cavitation emissions from the UCAs insonified by Doppler pulses were recorded using a passive cavitation detection system and stable and inertial cavitation thresholds ascertained. Loss of echogenicity from ELIP and Definity® was assessed within regions of interest on B-mode images. A numerical model based on UCA rupture predicted the functional form of the loss of echogenicity from ELIP and Definity®. Stable and inertial cavitation thresholds were found to have a weak dependence on pulse duration. Stable cavitation thresholds were lower than inertial cavitation thresholds. The power of cavitation emissions was an exponential function of the loss of echogenicity over the investigated range of acoustic pressures. Both ELIP and Definity® lost more than 80% echogenicity before the onset of stable or inertial cavitation. Once this level of echogenicity loss occurred, both stable and inertial cavitation were detected in the physiologic flow phantom. These results imply that stable and inertial cavitation are necessary in order to trigger complete loss of echogenicity acoustically from UCAs and this finding can be used when planning diagnostic and therapeutic applications.

  18. Comparison of swirling strengths derived from two- and three-dimensional velocity fields in channel flow

    NASA Astrophysics Data System (ADS)

    Chen, Huai; Li, Danxun; Bai, Ruonan; Wang, Xingkui

    2018-05-01

    Swirling strength is an effective vortex indicator in wall turbulence, and it can be determined based on either two-dimensional (2D) or three-dimensional (3D) velocity fields, written as λci2D and λci3D, respectively. A comparison between λci2D and λci3D has been made in this paper in sliced XY, YZ, and XZ planes by using 3D DNS data of channel flow. The magnitude of λci2D in three orthogonal planes differs in the inner region, but the difference tends to diminish in the outer flow. The magnitude of λci3D exceeds each λci2D, and the square of λci3D is greater than the summation of squares of three λci2D. Extraction with λci2D in XY, YZ, and XZ planes yields different population densities and vortex sizes, i.e., in XZ plane, the vortices display the largest population density and the smallest size, and in XY and YZ planes the vortices are similar in size but fewer vortices are extracted in the XY plane in the inner layer. Vortex size increases inversely with the threshold used for growing the vortex region from background turbulence. When identical thresholds are used, the λci3D approach leads to a slightly smaller population density and a greater vortex radius than the λci2D approach. A threshold of 0.8 for the λci3D approach is approximately equivalent to a threshold of 1.5 for the λci2D approach.

  19. Data center cooling method

    DOEpatents

    Chainer, Timothy J.; Dang, Hien P.; Parida, Pritish R.; Schultz, Mark D.; Sharma, Arun

    2015-08-11

    A method aspect for removing heat from a data center may use liquid coolant cooled without vapor compression refrigeration on a liquid cooled information technology equipment rack. The method may also include regulating liquid coolant flow to the data center through a range of liquid coolant flow values with a controller-apparatus based upon information technology equipment temperature threshold of the data center.

  20. Analysis of the threshold switching mechanism of a Te-SbO selector device for crosspoint nonvolatile memory applications

    NASA Astrophysics Data System (ADS)

    Kim, Young Seok; Park, Ji Woon; Lee, Jong Ho; Choi, In Ah; Heo, Jaeyeong; Kim, Hyeong Joon

    2017-10-01

    The threshold switching mechanism of Te-SbO thin films with a unique microstructure in which a Te nanocluster is present in the SbO matrix is analyzed. During the electro-forming process, amorphous Te filaments are formed in the Te nanocluster. However, unlike conventional Ovonic threshold switching (TS) selector devices, it has been demonstrated that the off-current flows along the filament. Numerical calculations show that the off-current is due to the trap present in the filament. We also observed changes in TS parameters through controls in the strength or volume of the filaments.

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