Ropponen, Annina; Svedberg, Pia; Koskenvuo, Markku; Silventoinen, Karri; Kaprio, Jaakko
2014-06-01
Physical work loading and psychological stress commonly co-occur in working life, hence potentially having an interrelationship that may affect work incapacity. This prospective cohort study aimed to investigate the effect of stability and change in physical work loading and stress on the risk of disability pension (DP) due to musculoskeletal diagnoses (MSD), while accounting for familial confounding in these associations. Data on 12,455 twins born before 1958 were surveyed of their physical work loading and psychological stress of daily activities in 1975 and 1981. The follow-up data was collected from pension registers until 2004. Cox proportional hazards regression models were used. During the follow up, 893 participants were granted DP due to MSD. Stable high (hazard ratio, HR, 2.21), but also increased physical work loading (HR 2.05) and high psychological stress (HR 2.22) were associated with increased risk for DP, and had significant interaction (p=0.032). The associations were confirmed when accounting for several confounding factors. Stable high but also increased physical work loading and psychological stress of daily activities between two timepoints with 6 years apart confirms their predictive role for an increased risk of DP. Both physical work loading and psychological stress seem to be independent from various confounding factors hence suggesting direct effect on risk for DP providing potential for occupational health care to early identification of persons at risk. © 2014 the Nordic Societies of Public Health.
Josephson, M; Pernold, G; Ahlberg-Hultén, G; Härenstam, A; Theorell, T; Vingård, E; Waldenström, M; Hjelm, E W
1999-01-01
This study investigated whether there is a relationship between high physical work load and adverse psychosocial work factors, and whether this relationship is different for women and men. Separate analyses for female registered nurses and assistant nurses were made because these are common occupations involving high physical and psychological demands. This study was part of the MUSIC-Norrtälje study, a population study with the overall aim of identifying risk factors for musculoskeletal disorders. The respondents, 1423 gainfully employed men and women, were randomly selected from the study population. The exposure assessments referred to a typical workday during the previous 12 months. Physical exposure was investigated by interview, psychosocial work factors by interview and questionnaire. For the women, but not the men, mainly routine work and a job strain situation, according to the model of Karasek and Theorell, increased the probability of having a high physical work load, assessed as a time-weighted average of energy expenditure in multiples of the resting metabolic rate. Results indicated that in female-dominated occupations, high physical work load might also imply adverse psychosocial conditions. A higher frequency of high physical work load and job strain was observed among assistant nurses compared with registered nurses. Covariance between physical and psychosocial demands makes it difficult to determine the relative influence of each in health problems. Results of the present study imply that this is a larger problem in studies of women than men.
Kausto, Johanna; Miranda, Helena; Pehkonen, Irmeli; Heliövaara, Markku; Viikari-Juntura, Eira; Solovieva, Svetlana
2011-10-01
There is growing evidence that physical and psychosocial exposures at work increase the risk of musculoskeletal disorders. The aim of this study was to describe the distribution and co-occurrence of these risk factors in the working population. We used data from the Health 2000 survey carried out in Finland in 2000-2001. The sample of our study consisted of 2,491 men and 2,613 women who had been actively working during the year preceding the survey. Logistic regression and exploratory factor analysis were used to analyze the co-occurrence of the work-related risk factors. Exposure to high physical work load and several co-occurring work load factors was more prevalent among men than women. In women, as opposed to men, the highest exposure to most physical work load factors was found in their later work life. Gender and age showed weak associations with psychosocial work load factors. Low socioeconomic position, in both genders, was related to an increased risk of being exposed to several co-occurring physical or psychosocial factors. Physical exposures most frequently co-occurred with high job demands and low job control in men. Among women, physical exposures were found to co-occur with high job demands, low job control and job insecurity. This study provides novel information on the occupational exposures in general working population. It appears that co-occurrence of physical and psychosocial exposures should be considered in research and prevention of musculoskeletal disorders. In addition, a broader set of occupational factors, e.g., work organization, are suggested to be included in future studies to cover all the relevant determinants.
DOT National Transportation Integrated Search
2013-08-01
The objective of this work, Pilot Project - Demonstration of Capabilities and Benefits of Bridge Load Rating through Physical Testing, was to demonstrate the capabilities for load testing and rating bridges in Iowa, study the economic benefit of perf...
DOT National Transportation Integrated Search
2013-08-01
The objective of this work, Pilot Project - Demonstration of Capabilities and Benefits of Bridge Load Rating through Physical Testing, was to demonstrate the capabilities for load testing and rating bridges in Iowa, study the economic benefit of perf...
DOT National Transportation Integrated Search
2013-08-01
The objective of this work, Pilot Project - Demonstration of Capabilities and Benefits of Bridge Load Rating through Physical Testing, was to demonstrate the capabilities for load testing and rating bridges in Iowa, study the economic benefit of perf...
Appraisal of work ability in relation to job-specific health requirements in ambulance workers.
van Schaaijk, A; Boschman, J S; Frings-Dresen, M H W; Sluiter, J K
2017-01-01
To gain insight into which job-specific health requirements relate to work ability, the following two research questions were formulated: Which job-specific health requirements are associated with the appraisal of work ability in ambulance drivers and paramedics? How are appraisals of physical and mental work ability associated with the appraisal of overall work ability in ambulance drivers and paramedics? Workers Health Surveillance cross-sectional data of 506 ambulance workers (236 drivers and 270 paramedics) were used. The tests for specific job requirements were divided into six categories. Work ability was appraised as overall, physical and mental/emotional. Multiple linear stepwise regression analyses were used to model the associations. Outcomes in 'raised alertness and judgment ability' (R 2 = 0.09), 'job-specific physical abilities' (R 2 = 0.10) and 'emotional peak load' (R 2 = 0.07) significantly explained appraised overall, physical and mental/emotional work ability. Physical and mental/emotional work ability together explained 48.3% of the variance of overall work ability. The explained variance by physical and mental/emotional work ability was almost 4% higher in drivers than in paramedics. Overall work ability was significantly explained by outcomes in 'raised alertness and judgment ability' and 'emotional peak load.' Physical work ability was significantly explained by 'job-specific physical abilities' and 'raised alertness and judgment ability' outcomes, while 'emotional peak load' and 'raised alertness and judgment ability' outcomes significantly explained mental/emotional work ability. Physical and mental/emotional work ability explains the same proportion of variance in overall work ability.
Effects of physical and mental stressors on muscle pain.
Westgaard, R H
1999-01-01
Physical and mental stressors as risk factors for pain development are discussed. These multifaceted stressor terms are narrowed down so that physical stressors are represented by muscle activity recorded by electromyography (EMG), while mental stress is considered synonymous with psychosocial stress in vocational studies; in experimental studies cognitive stress is used as a model. Pain in the shoulder and neck are focused and related to EMG recordings of activity in the trapezius muscle. Major challenges in this field include proper risk assessment at low physical work loads and criteria for evaluating stress as a risk factor. A 3-factor conceptual model is presented in which the independent dimensions physical work load, mental stress, and individual sensitivity determine the risk of shoulder and neck complaints. It is pointed out that a predominant reduction in physical work load for many jobs and an increasing interaction between work conditions and the general life situation of workers pose particular challenges for risk assessment.
Physical workload and thoughts of retirement.
Perkiö-Mäkelä, Merja; Hirvonen, Maria
2012-01-01
The aim of this paper is to present Finnish employees' opinions on continuing work until retirement pension and after the age of 63, and to find out if physical workload is related to these opinions. Altogether 39% of men and 40% of women had never had thoughts of early retirement, and 59% claimed (both men and women) that they would consider working beyond the age of 63. Own health (20%); financial gain such as salary and better pension (19%); meaningful, interesting and challenging work (15%); flexible working hours or part-time work (13%); lighter work load (13%); good work community (8%); and good work environment (6%) were stated as factors affecting the decision to continue working after the age of 63. Employees whose work involved low physical workload had less thoughts of early retirement and had considered continuing work after the age of 63 more often than those whose work involved high physical loads. Own health in particular was stated as a reason to consider continuing work by employees whose work was physically demanding.
Principles for classification of work load for women
NASA Technical Reports Server (NTRS)
Navakatikyan, A. O.; Okhrimenko, A. P.; Karakashyan, A. N.; Buzunov, V. A.
1980-01-01
In an attempt to develop guidelines for classification by degree of intensity of various kinds of physical work performed by women, the effects of different work loads on women as compared to men were studied under industrial and experimental conditions, including response of the cardiovascular and respiratory systems to specified physical exercises of increasing intensity. Physiological criteria for assessing female labor in terms of intensity are proposed.
Compensation for Adolescents' School Mental Load by Physical Activity on Weekend Days.
Kudláček, Michal; Frömel, Karel; Jakubec, Lukáš; Groffik, Dorota
2016-03-09
Increasing mental load and inadequate stress management significantly affect the efficiency, success and safety of the educational/working process in adolescents. The objective of this study is to determine the extent that adolescents compensate for their school mental load by physical activity (PA) on weekend days and, thus, to contribute to the objective measurement of mental load in natural working conditions. A cross-sectional study was conducted between September 2013 and April 2014. A set of different methods was employed-self-administered questionnaire (IPAQ-long questionnaire), objective measurements-pedometers, and accelerometers (ActiTrainers). They was distributed to 548 students from 17 high schools. Participants' mental load was assessed based on the difference between PA intensity and/or physical inactivity and heart rate range. The participants with the highest mental load during school lessons do not compensate for this load by PA on weekend days. Adolescents need to be encouraged to be aware of their subjective mental load and to intentionally compensate for this load by PA on weekend days. It is necessary to support the process of adopting habits by sufficient physical literacy of students, as well as teachers, and by changes in the school program.
The impact of working technique on physical loads - an exposure profile among newspaper editors.
Lindegård, A; Wahlström, J; Hagberg, M; Hansson, G-A; Jonsson, P; Wigaeus Tornqvist, E
2003-05-15
The aim of this study was to investigate the possible associations between working technique, sex, symptoms and level of physical load in VDU-work. A study group of 32 employees in the editing department of a daily newspaper answered a questionnaire, about physical working conditions and symptoms from the neck and the upper extremities. Muscular load, wrist positions and computer mouse forces were measured. Working technique was assessed from an observation protocol for computer work. In addition ratings of perceived exertion and overall comfort were collected. The results showed that subjects classified as having a good working technique worked with less muscular load in the forearm (extensor carpi ulnaris p=0.03) and in the trapezius muscle on the mouse operating side (p=0.02) compared to subjects classified as having a poor working technique. Moreover there were no differences in gap frequency (number of episodes when muscle activity is below 2.5% of a reference contraction) or muscular rest (total duration of gaps) between the two working technique groups. Women in this study used more force (mean force p=0.006, peak force p=0.02) expressed as % MVC than the men when operating the computer mouse. No major differences were shown in muscular load, wrist postures, perceived exertion or perceived comfort between men and women or between cases and symptom free subjects. In conclusion a good working technique was associated with reduced muscular load in the forearm muscles and in the trapezius muscle on the mouse operating side. Moreover women used more force (mean force and peak force) than men when operating the click button (left button) of the computer mouse.
Predicting physiological capacity of human load carriage - a review.
Drain, Jace; Billing, Daniel; Neesham-Smith, Daniel; Aisbett, Brad
2016-01-01
This review article aims to evaluate a proposed maximum acceptable work duration model for load carriage tasks. It is contended that this concept has particular relevance to physically demanding occupations such as military and firefighting. Personnel in these occupations are often required to perform very physically demanding tasks, over varying time periods, often involving load carriage. Previous research has investigated concepts related to physiological workload limits in occupational settings (e.g. industrial). Evidence suggests however, that existing (unloaded) workload guidelines are not appropriate for load carriage tasks. The utility of this model warrants further work to enable prediction of load carriage durations across a range of functional workloads for physically demanding occupations. If the maximum duration for which personnel can physiologically sustain a load carriage task could be accurately predicted, commanders and supervisors could better plan for and manage tasks to ensure operational imperatives were met whilst minimising health risks for their workers. Copyright © 2015 Elsevier Ltd and The Ergonomics Society. All rights reserved.
ERIC Educational Resources Information Center
Saw, Kim Guan
2017-01-01
This article revisits the cognitive load theory to explore the use of worked examples to teach a selected topic in a higher level undergraduate physics course for distance learners at the School of Distance Education, Universiti Sains Malaysia. With a break of several years from receiving formal education and having only minimum science…
29 CFR 1919.76 - Safe working load reduction.
Code of Federal Regulations, 2010 CFR
2010-07-01
... load reduction. (a) If the operation in which equipment is engaged never utilizes more than a fraction... physically capable of operation at the original load rating and the load reduction is not for the purpose of...
Laaksonen, Mikko; Rahkonen, Ossi; Martikainen, Pekka; Lahelma, Eero
2006-03-01
To examine associations of job demands and job control, procedural and relational organizational fairness, and physical work load with self-rated general health and mental health. In addition, the effect of occupational class on these associations is examined. The data were derived from the Helsinki Health Study baseline surveys in 2001-2002. Respondents to cross-sectional postal surveys were middle-aged employees of the City of Helsinki (n=5.829, response rate 67%). Associations of job demands and job control, organizational fairness and physical work load with less than good self-rated health and poor GHQ-12 mental health were examined. Those with the poorest working conditions two to three times more, often reported poor general and mental health than those with the best working conditions. Adjustment for occupational class weakened the associations of low job control and physical work load with general health by one fifth, but even more strengthened that of high job demands. Adjustment for occupational class clearly strengthened the associations of job control and physical work load with mental health in men. Mutual adjustment for all working conditions notably weakened their associations with both health measures, except those of job control in men. All working conditions except relational organizational fairness remained independently associated with general and mental health. All studied working conditions were strongly associated with both general and mental health but the associations weakened after mutual adjustments. Of the two organizational fairness measures, procedural fairness remained independently associated with both health outcomes. Adjustment for occupational class had essentially different effects on the associations of different working conditions and different health outcomes.
Internal consistency and validity of a new physical workload questionnaire
Bot, S; Terwee, C; van der Windt, D A W M; Feleus, A; Bierma-Zeinstra, S; Knol, D; Bouter, L; Dekker, J
2004-01-01
Aims: To examine the dimensionality, internal consistency, and construct validity of a new physical workload questionnaire in employees with musculoskeletal complaints. Methods: Factor analysis was applied to the responses in three study populations with musculoskeletal disorders (n = 406, 300, and 557) on 26 items related to physical workload. The internal consistency of the resulting subscales was examined. It was hypothesised that physical workload would vary among different occupational groups. The occupations of all subjects were classified into four groups on the basis of expected workload (heavy physical load; long lasting postures and repetitive movements; both; no physical load). Construct validity of the subscales created was tested by comparing the subscale scores among these occupational groups. Results: The pattern of the factor loadings of items was almost identical for the three study populations. Two interpretable factors were found: items related to heavy physical workload loaded highly on the first factor, and items related to static postures or repetitive work loaded highly on the second factor. The first constructed subscale "heavy physical work" had a Cronbach's α of 0.92 to 0.93 and the second subscale "long lasting postures and repetitive movements", of 0.86 to 0.87. Six of eight hypotheses regarding the construct validity of the subscales were confirmed. Conclusions: The results support the internal structure, internal consistency, and validity of the new physical workload questionnaire. Testing this questionnaire in non-symptomatic employees and comparing its performance with objective assessments of physical workload are important next steps in the validation process. PMID:15550603
Dutch monitor on stress and physical load: risk factors, consequences, and preventive action.
Houtman, I L; Goudswaard, A; Dhondt, S; van der Grinten, M P; Hildebrandt, V H; van der Poel, E G
1998-02-01
Due to recent changes in legislation on occupational health and safety, a national monitor on stress and physical load was developed in The Netherlands to monitor (a) risks and consequences of stress and physical load at work, (b) preventive actions in companies to reduce these risks, and (c) organisational and environmental variables that facilitate preventive actions. Information was gathered from employers, employees, and employees' representatives. The monitor was used with a nationally representative sample of companies in industry, wholesale trade, and banking and finance, 782 companies in total. The information from the employees, aggregated at the company level, was not found to be correlated with that from the employer from the same companies. Although many employers do recognise risk factors for both physical load and stress as a problem they often seem to underestimate the problem when compared with employees or their representatives. This is particularly the case for psychosocial risk factors. Also, the perception of outcome measures, especially employers who consider emotional exhaustion to be work related, were fewer than the employees' representatives of the same organisation. Preventive measures on physical load are much more popular than measures against stress. It is the responsibility of the employer to take more preventive action of all kinds. They need to recognise risk factors as problems and health outcomes to be related to work. Employees of larger companies should participate with employers to consider effective measures, and more use should be made of support at branch level. For specific preventive measures, specific predictors emerged. Except for measures to prevent work stress, information from employees did not sufficiently contribute to the initiation of preventive measures in the workplace.
Dutke, Stephan; Jaitner, Thomas; Berse, Timo; Barenberg, Jonathan
2014-02-01
Research on effects of acute physical exercise on performance in a concurrent cognitive task has generated equivocal evidence. Processing efficiency theory predicts that concurrent physical exercise can increase resource requirements for sustaining cognitive performance even when the level of performance is unaffected. This hypothesis was tested in a dual-task experiment. Sixty young adults worked on a primary auditory attention task and a secondary interval production task while cycling on a bicycle ergometer. Physical load (cycling) and cognitive load of the primary task were manipulated. Neither physical nor cognitive load affected primary task performance, but both factors interacted on secondary task performance. Sustaining primary task performance under increased physical and/or cognitive load increased resource consumption as indicated by decreased secondary task performance. Results demonstrated that physical exercise effects on cognition might be underestimated when only single task performance is the focus.
[Physical work capacity in coal miners and industrial workers].
Benavides, R
1992-10-01
The aerobic work capacity of 220 coal miners aged 22 to 63 years with a high physical work load and 78 industrial workers aged 19 to 58 years with a relatively light work load was measured to observe if there was a relationship between the work load of these subjects and their aerobic work capacity. All the subjects were subjected to a medical examination, spirometry, chest x Rays and anthropometric measurements. Aerobic work capacity was indirectly estimated extrapolating pulse rates obtained al submaximal work loads in a bicycle ergometer to the calculated maximal cardiac frequency for age. Aerobic work capacity was not different between coal miners and industrial workers, either measured as absolute values (2.43 +/- 0.41 and 2.5 +/- 0.49 l/min respectively) or as relative values (43.2 +/- 6.9 and 43.4 +/- 8.2 ml/kg lean body mass respectively). These values decreased with age in the same proportion in both groups (0.24 l/min per decade). Lean body mass was significantly higher in industrial workers and decreased significantly with age only in coal miners. Considering published energy requirements for mine labors, none of the studied miners should work as digger and a high proportion of the other workers would be exposed to hazardous work loads to their health. The fact that over 50% of these subjects can efficiently fulfill their jobs may indicate that they have a high anaerobic work capacity. This hypothesis needs confirmation with future studies.
Torgén, M; Winkel, J; Alfredsson, L; Kilbom, A
1999-06-01
The principal aim of the present study was to evaluate questionnaire-based information on past physical work loads (6-year recall). Effects of memory difficulties on reproducibility were evaluated for 82 subjects by comparing previously reported results on current work loads (test-retest procedure) with the same items recalled 6 years later. Validity was assessed by comparing self-reports in 1995, regarding work loads in 1989, with worksite measurements performed in 1989. Six-year reproducibility, calculated as weighted kappa coefficients (k(w)), varied between 0.36 and 0.86, with the highest values for proportion of the workday spent sitting and for perceived general exertion and the lowest values for trunk and neck flexion. The six-year reproducibility results were similar to previously reported test-retest results for these items; this finding indicates that memory difficulties was a minor problem. The validity of the questionnaire responses, expressed as rank correlations (r(s)) between the questionnaire responses and workplace measurements, varied between -0.16 and 0.78. The highest values were obtained for the items sitting and repetitive work, and the lowest and "unacceptable" values were for head rotation and neck flexion. Misclassification of exposure did not appear to be differential with regard to musculoskeletal symptom status, as judged by the calculated risk estimates. The validity of some of these self-administered questionnaire items appears sufficient for a crude assessment of physical work loads in the past in epidemiologic studies of the general population with predominantly low levels of exposure.
Kouvonen, Anne; Mänty, Minna; Lallukka, Tea; Pietiläinen, Olli; Lahelma, Eero; Rahkonen, Ossi
2017-07-12
To investigate whether changes in psychosocial and physical working conditions are associated with subsequent psychotropic medication in ageing employees. Data were from the Helsinki Health Study, a cohort study of Finnish municipal employees, aged 40-60 years at phase 1 (2000-2002). Changes in psychosocial and physical working conditions were measured between phase 1 and phase 2 (2007). Survey data were longitudinally linked to data on prescribed, reimbursed psychotropic medication purchases (Anatomical Therapeutic Chemical) obtained from the registers of the Social Insurance Institution of Finland between the phase 2 survey and December 2013 (N=3587; 80% women). Outcomes were any psychotropic medication; antidepressants (N06A); anxiolytics (N05B); and sedatives and hypnotics (N05C). Cox regression analyses were performed. During the follow-up, 28% of the participants were prescribed psychotropic medication. Repeated exposures to low job control, high job demands and high physical work load were associated with an increased risk of subsequent antidepressant and anxiolytic medication. Increased and repeated exposure to high physical work load, increased job control and repeated high job demands were associated with subsequent sedative and hypnotic medication. Age and sex-adjusted HR varied from 1.18 to 1.66. Improvement in job control was associated with a lower risk of anxiolytic, but with a higher risk of sedatives and hypnotic medication. Decreased physical work load was associated with a lower risk of antidepressant and anxiolytic medications. Improvement in working conditions could lower the risk of mental ill-health indicated by psychotropic medication. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
Actoprotective effect of ginseng: improving mental and physical performance
Oliynyk, Sergiy; Oh, Seikwan
2013-01-01
Actoprotectors are preparations that increase the mental performance and enhance body stability against physical loads without increasing oxygen consumption. Actoprotectors are regarded as a subclass of adaptogens that hold a significant capacity to increase physical performance. The focus of this article is studying adaptogen herbs of genus Panax (P. ginseng in particular) and their capabilities as actoprotectors. Some animal experiments and human studies about actoprotective properties of genus Panax attest that P. ginseng (administered as an extract) significantly increased the physical and intellectual work capacities, and the data provided suggests that ginseng is a natural source of actoprotectors. Preparations of ginseng can be regarded as potential actoprotectors which give way to further research of its influence on physical and mental work capacity, endurance and restoration after exhaustive physical loads while compared with reference actoprotectors. PMID:23717168
Visser, Steven; van der Molen, Henk F; Kuijer, P Paul F M; Hoozemans, Marco J M; Frings-Dresen, Monique H W
2014-11-01
The objective of this study was to assess differences in work demands, energetic workload and workers' discomfort and physical effort in two regularly observable workdays in ironwork; one where loads up to 50kg were handled with two persons manually (T50) and one where loads up to 100kg were handled manually with four persons (T100). Differences between these typical workdays were assessed with an observational within-subject field study of 10 ironworkers. No significant differences were found for work demands, energetic workload or discomfort between T50 and T100 workdays. During team lifts, load mass exceeded 25kg per person in 57% (T50 workday) and 68% (T100 workday) of the lifts. Seven ironworkers rated team lifting with two persons as less physically demanding compared with lifting with four persons. When loads heavier than 25kg are lifted manually with a team, regulations of the maximum mass weight are frequently violated. Loads heavier than 25kg are frequently lifted during concrete reinforcement work and should be lifted by a team of persons. However, the field study showed that loads above 25kg are most of the time not lifted with the appropriate number of workers. Therefore, loads heavier than 25kg should be lifted mechanically. Copyright © 2014 Elsevier Ltd and The Ergonomics Society. All rights reserved.
Yassi, Annalee
2015-04-01
Implications for practice and research: Physical, organisational and social aspects of work significantly contribute to musculoskeletal pain in nurses, along with nonoccupational contextual and personal factors. Measures to prevent neck, shoulder and back pain in nurses should be implemented for nurses from the very beginning of their training programmes, while modifications to overtime work and physical loads should be seriously considered. Preventive measures targeting overtime work, physical workload and psychosocial factors need investigating further.
Rozhkova, E A; Ordzhonikidze, Z G; Druzhinin, A E; Seĭfulla, N R; Paniushkin, V V; Kuznetsov, Iu M
2007-01-01
The effects of a submaximum single physical load with a mixed aerobic-anaerobic character (combined rowing test) on the intensity of lipid peroxidation (LPO) processes, antioxidant state of the organism, and rheological properties of blood have been studied in a group of athletes. The administration of natural antioxidants significantly decreased the LPO stress induced by the physical load, reduced the suppression of the antioxidant system of the organism, and normalized the LPO-disturbed hemorheological parameters. Antioxidants such as carnosine, cytamine, and apilac can be used as non-doping means for the accelerated recovery and increase in the physical work capacity in athletes.
Physical Activity as Cause and Cure of Muscular Pain: Evidence of Underlying Mechanisms
Søgaard, Karen; Sjøgaard, Gisela
2017-01-01
Work-related physical activity (PA), in terms of peak loads and sustained and/or repetitive contractions, presents risk factors for the development of muscular pain and disorders. However, PA as a training tailored to the employee’s work exposure, health, and physical capacity offers prevention and rehabilitation. We suggest the concept of “Intelligent Physical Exercise Training” relying on evidence-based sports science training principles. PMID:28418998
Effect of block weight on work demands and physical workload during masonry work.
Van Der Molen, H F; Kuijer, P P F M; Hopmans, P P W; Houweling, A G; Faber, G S; Hoozemans, M J M; Frings-Dresen, M H W
2008-03-01
The effect of block weight on work demands and physical workload was determined for masons who laid sandstone building blocks over the course of a full work day. Three groups of five sandstone block masons participated. Each group worked with a different block weight: 11 kg, 14 kg or 16 kg. Productivity and durations of tasks and activities were assessed through real time observations at the work site. Energetic workload was also assessed through monitoring the heart rate and oxygen consumption at the work site. Spinal load of the low back was estimated by calculating the cumulated elastic energy stored in the lumbar spine using durations of activities and previous data on corresponding compression forces. Block weight had no effect on productivity, duration or frequency of tasks and activities, energetic workload or cumulative spinal load. Working with any of the block weights exceeded exposure guidelines for work demands and physical workload. This implies that, regardless of block weight in the range of 11 to 16 kg, mechanical lifting equipment or devices to adjust work height should be implemented to substantially lower the risk of low back injuries.
Physical load during work and leisure time as risk factors for back pain.
Hoogendoorn, W E; van Poppel, M N; Bongers, P M; Koes, B W; Bouter, L M
1999-10-01
This systematic review assessed aspects of physical load during work and leisure time as risk factors for back pain. Several reviews on this topic are available, but this one is based on a strict systematic approach to identify and summarize the evidence, comparable with that applied in the clinical literature on the efficacy of intervention for back pain. A computerized bibliographical search was made of several data bases for studies with a cohort or case-referent design. Cross-sectional studies were excluded. A rating system was used to assess the strength of the evidence, based on the methodological quality of 28 cohort and 3 case-referent studies and the consistency of the findings. Strong evidence exists for manual materials handling, bending and twisting, and whole-body vibration as risk factors for back pain. The evidence was moderate for patient handling and heavy physical work, and no evidence was found for standing or walking, sitting, sports, and total leisure-time physical activity.
Karlqvist, Lena K; Härenstam, Annika; Leijon, Ola; Schéele, Patrik
2003-10-01
This study attempted to identify work and leisure-time conditions and life-style factors associated with excess metabolic levels (metabolic demands exceeding one-third of a person's aerobic capacity) at work among men and women. The study focused upon psychological, ergonomic, and physically loading factors and chemical and physical environmental conditions. Data were obtained through self-reports, interviews, workplace analyses, technical measurements, and observations. Gender-specific calculations were used in univariate analyses and in stepwise logistic regression models for excess metabolic level. Twenty-seven percent of the men and twenty-two percent of the women worked at an excess metabolic level during their workday. Awkward work postures, heavy manual materials handling, high circulatory strain, chemical exposures, noise levels, much routine work, and many obstacles to job performance characterized their work conditions. The women had low skill discretion and more often atypical workhours, while the men showed high circulatory strain during leisure-time activities. Important negative life-style factors were a high consumption of alcohol for the men and a high body mass index and no or little regular physical exercise for the women. Metabolic demands in worklife today remain high. The women who exceeded the recommended metabolic level at work in this study were characterized by low pay, poor health, and children at home, in addition to high physical load and psychosocial strain at work. These characteristics indicate a group with few possibilities to leave a hazardous job for a less physically demanding one. The men who worked at an excess metabolic level seemed to be characterized more by a life-style common in some male-dominated work cultures with monotonous work.
Impact of work boots and load carriage on the gait of oil rig workers.
Tian, Miao; Park, Huiju; Koo, Heekwang; Xu, Qinwen; Li, Jun
2017-03-01
Effects of work boots and load carriage (6.4 kg and 12.8 kg) on gait pattern were investigated. The protective work boots were examined by comparison with running shoes through human performance tests with 15 male participants. The loads were carried symmetrically and asymmetrically on the shoulder and hand. Statistical data analysis showed a prolonged stance phase and decreased double support for work boots. A significantly increased ground reaction force was found in work boot conditions as the weight of loads increases. This study demonstrates that inflexible and heavy work boots restrict foot movement and require greater torque at the ankle to propel the body forward, which may increase physical strain and the risk of musculoskeletal injuries. Development of improved fixation methods for work boots, increased use of flexible protective layers and further study of anthropometry of human foot morphology for improved safety and work efficiency of industry workers are suggested.
Suspension Bridges: A Merger of Physics, Engineering, and Art
ERIC Educational Resources Information Center
Greenslade, Thomas B., Jr.
1974-01-01
Discusses the physical principles underlying the design of a small scale suspension bridge, including its types and strength calculations. Included are the working equation and two formulas for determining the load per unit length. (CC)
NASA Astrophysics Data System (ADS)
Kudryashov, E. A.; Smirnov, I. M.; Grishin, D. V.; Khizhnyak, N. A.
2018-06-01
The work is aimed at selecting a promising grade of a tool material, whose physical-mechanical characteristics would allow using it for processing the surfaces of discontinuous parts in the presence of shock loads. An analysis of the physical-mechanical characteristics of most common tool materials is performed and the data on a possible provision of the metal-working processes with promising composite grades are presented.
2010-01-01
Background Physical therapists working in the State of Kuwait are at risk of work-related musculoskeletal disorders (WMSDs). However, prevalence rates and risk factors are not well documented. The objective of this study was to determine the prevalence, characteristics, and impacts of WMSDs among physical therapists in the State of Kuwait. Methods A self-administered questionnaire was distributed to 350 physical therapists. The questionnaire gathered demographic data as well as information on occurrence of musculoskeletal complaints in the previous 12 months. Descriptive statistics, frequency, and Chi-square analyses were used. Results The response rate to the questionnaire was 63% (222/350). Of the 212 responders included in the study, the one-year prevalence of WMSDs was 47.6%, with lower back complaints as the most common (32%). This was followed by neck (21%), upper back (19%), shoulder (13%), hand/wrist (11%), knee (11%), ankle/foot (6%), elbow (4%), and hip/thigh (3%) complaints. The frequency of WMSDs was not gender related (except lower back, neck, and shoulder complaints) nor was it related to age (except lower back complaints), working venues (except hand/wrist), working hours, area of specialty, or exercise. WMSDs' impact on work was minor. Conclusions WMSDs among physical therapists in Kuwait were common, with lower back and neck affected most. Lower back and neck WMSDs were related to the participant's demographics. Hand/wrist WMSDs were related to work settings. Further research is needed to investigate the effect of risk factors as physical load, psychosocial load, and general health status on prevalence musculoskeletal disorders. PMID:20540724
Circadian rhythms as a basis for work organization: a study with live line electricians.
Guimarães, Lia Buarque de Macedo; Ribeiro, Jose Luis Duarte; Saurin, Tarcísio Abreu; de Bittencourt Júnior, Paulo Ivo Homem
2013-02-01
With the assumption that circadian rhythms influence human performance, the work of live line electricians was reorganized and evaluated. The hypothesis was that in highly physical and attention-demanding work, the organization of tasks, according to the ideal period of day and day of week, should diminish stress and consequent work risks. There are only a few studies reporting the work of electricians and even fewer approaching work organization. Moreover, these investigations often do not consider human physiological limitations and capabilities as well as task demands. A new work system was proposed with consideration of (a) the circadian cycles and homeostatic processes; (b) the effect of heat, which is a zeitgeber (synchronizer) for the biological clocks; and (c) the degree of physical and mental demands of the different performed tasks, which was assessed on the basis of opinions of the electricians and physiological markers of stress that are controlled by circadian rhythms. The traditional and new systems were compared on the basis of two cognitive indices (the arrangement of matchsticks and the perception of a minute) and three physiological markers of mental-to-physical loads (heart frequency and the level of adrenaline and noradrenaline). Both physical and mental loads were reduced in the new system. Work organization should include consideration of human circadian rhythms, mainly when stressful and high-risk tasks are involved. The findings can be applied in any work design, but they are especially suited for highly demanding work carried out outdoors.
Commercial porters of eastern Nepal: health status, physical work capacity, and energy expenditure.
Malville, N J; Byrnes, W C; Lim, H A; Basnyat, R
2001-01-01
The purpose of the study was to compare full-time hill porters in eastern Nepal with part-time casual porters engaged primarily in subsistence farming. The 50 porters selected for this study in Kenja (elevation 1,664 m) were young adult males of Tibeto-Nepali origin. Following standardized interviews, anthropometry, and routine physical examinations, the porters were tested in a field laboratory for physiological parameters associated with aerobic performance. Exercise testing, using a step test and indirect calorimetry, included a submaximal assessment of economy and a maximal-effort graded exercise test. Energy expenditure was measured in the field during actual tumpline load carriage. No statistically significant differences were found between full-time and part-time porters with respect to age, anthropometric characteristics, health, nutritional status, or aerobic power. Mean VO2 peak was 2.38 +/- 0.27 L/min (47.1 +/- 5.3 ml/kg/min). Load-carrying economy did not differ significantly between porter groups. The relationship between VO2 and load was linear over the range of 10-30 kg with a slope of 9 +/- 4 ml O2/min per kg of load. During the field test of actual work performance, porters expended, on average, 348 +/- 68 kcal/hr in carrying loads on the level and 408 +/- 60 kcal/hr in carrying loads uphill. Most porters stopped every 2 min, on average, to rest their loads briefly on T-headed resting sticks (tokmas). The technique of self-paced, intermittent exercise together with the modest increase in energy demands for carrying increasingly heavier loads allows these individuals to regulate work intensity and carry extremely heavy loads without creating persistent medical problems.
Role of the adrenocortical reaction to physical load in increase in the working capacity of the body
NASA Technical Reports Server (NTRS)
Viru, A. A.
1977-01-01
The maximal duration of swimming by rats with a load of 3% of their body weight increased after 5 weeks of training. This time did not increase in animals receiving dexamethasone in the process of training. The blood corticosterone level of these rats with the maximal load increased less than that of animals trained without administration of dexamethasone.
Ageing, working hours and work ability.
Costa, G; Sartori, S
2007-11-01
The current paper reports the main results of several studies carried out on Italian workers using the work ability index as a complementary tool for workers' periodical health surveillance. The work ability index shows a general decreasing trend over the years, but it changes differently according to working conditions and personal health status. In jobs with higher mental involvement and autonomy, but lower physical constraint, it remains quite constant and high over the years, while it significantly decreases with a steeper trend the higher the physical work load and the lower the job control are. Sex and working hours appear to act concurrently in influencing work ability, particularly in association with more physically demanding jobs. It is therefore necessary to adopt flexible interventions, able to give ageing shift workers a proper support for maintaining a satisfactory work ability, by means of actions addressed both to work organization and psycho-physical conditions.
Kontosic, I; Vukelić, M; Pancić, M; Kunisek, J
1994-12-01
Physical work load was estimated in a female conveyor-belt worker in a bottling plant. Estimation was based on continuous measurement and on calculation of average heart rate values in three-minute and one-hour periods and during the total measuring period. The thermal component of the heart rate was calculated by means of the corrected effective temperature, for the one-hour periods. The average heart rate at rest was also determined. The work component of the heart rate was calculated by subtraction of the resting heart rate and the heart rate measured at 50 W, using a regression equation. The average estimated gross energy expenditure during the work was 9.6 +/- 1.3 kJ/min corresponding to the category of light industrial work. The average estimated oxygen uptake was 0.42 +/- 0.06 L/min. The average performed mechanical work was 12.2 +/- 4.2 W, i.e. the energy expenditure was 8.3 +/- 1.5%.
Physical working conditions as covered in European monitoring questionnaires.
Tynes, Tore; Aagestad, Cecilie; Thorsen, Sannie Vester; Andersen, Lars Louis; Perkio-Makela, Merja; García, Francisco Javier Pinilla; Blanco, Luz Galiana; Vermeylen, Greet; Parent-Thirion, Agnes; Hooftman, Wendela; Houtman, Irene; Liebers, Falk; Burr, Hermann; Formazin, Maren
2017-06-05
The prevalence of workers with demanding physical working conditions in the European work force remains high, and occupational physical exposures are considered important risk factors for musculoskeletal disorders (MSD), a major burden for both workers and society. Exposures to physical workloads are therefore part of the European nationwide surveys to monitor working conditions and health. An interesting question is to what extent the same domains, dimensions and items referring to the physical workloads are covered in the surveys. The purpose of this paper is to determine 1) which domains and dimensions of the physical workloads are monitored in surveys at the national level and the EU level and 2) the degree of European consensus among these surveys regarding coverage of individual domains and dimensions. Items on physical workloads used in one European wide/Spanish and five other European nationwide work environment surveys were classified into the domains and dimensions they cover, using a taxonomy agreed upon among all participating partners. The taxonomy reveals that there is a modest overlap between the domains covered in the surveys, but when considering dimensions, the results indicate a lower agreement. The phrasing of items and answering categories differs between the surveys. Among the domains, the three domains covered by all surveys are "lifting, holding & carrying of loads/pushing & pulling of loads", "awkward body postures" and "vibrations". The three domains covered less well, that is only by three surveys or less, are "physical work effort", "working sitting", and "mixed exposure". This is the fırst thorough overview to evaluate the coverage of domains and dimensions of self-reported physical workloads in a selection of European nationwide surveys. We hope the overview will provide input to the revisions and updates of the individual countries' surveys in order to enhance coverage of relevant domains and dimensions in all surveys and to increase the informational value of the surveys.
Recruitment of Secondary School Physics Teachers--An International Viewpoint.
ERIC Educational Resources Information Center
Mayfield, M. R.
This report of the findings of the working group on "recruitment" of the International Congress on the Education of Secondary School Physics Teachers held in Hungary in September, 1970, includes reasons for the shortage of physics teachers (low salaries, excessive class load, lack of prestige, and inadequate programs of teacher preparation),…
Simulation of Propellant Loading System Senior Design Implement in Computer Algorithm
NASA Technical Reports Server (NTRS)
Bandyopadhyay, Alak
2010-01-01
Propellant loading from the Storage Tank to the External Tank is one of the very important and time consuming pre-launch ground operations for the launch vehicle. The propellant loading system is a complex integrated system involving many physical components such as the storage tank filled with cryogenic fluid at a very low temperature, the long pipe line connecting the storage tank with the external tank, the external tank along with the flare stack, and vent systems for releasing the excess fuel. Some of the very important parameters useful for design purpose are the prediction of pre-chill time, loading time, amount of fuel lost, the maximum pressure rise etc. The physics involved for mathematical modeling is quite complex due to the fact the process is unsteady, there is phase change as some of the fuel changes from liquid to gas state, then conjugate heat transfer in the pipe walls as well as between solid-to-fluid region. The simulation is very tedious and time consuming too. So overall, this is a complex system and the objective of the work is student's involvement and work in the parametric study and optimization of numerical modeling towards the design of such system. The students have to first become familiar and understand the physical process, the related mathematics and the numerical algorithm. The work involves exploring (i) improved algorithm to make the transient simulation computationally effective (reduced CPU time) and (ii) Parametric study to evaluate design parameters by changing the operational conditions
[Evaluation of ergonomic load of clinical nursing procedures].
Yan, P; Zhang, L; Li, F Y; Yang, Y; Wang, Y N; Huang, A M; Dai, Y L; Yao, H
2017-08-20
Objective: To evaluate the ergonomic load of clinical nursing procedures and to provide evidence for the prevention and management of work-related musculoskeletal disorders (WMSDs) in nurses. Methods: Based on the nursing unit characteristics and the common departments involving patient-turning procedures, 552 nurses were selected from 6 clinical departments from July to September, 2016. The ergonomic load of four types of patient-turning procedures, i.e., turning the patient's body, changing the bed linen of in-bed patients, moving patients, and chest physiotherapy, was evaluated by the on-site inspectors and self-evaluated by the operators using the Quick Exposure Check. The exposure value, exposure level, and exposure rate of WMSDs were assessed based on the procedure-related physical loads on the back, shoulders/arms, wrists/hands and neck, as well as the loads from work rhythm and work pressure. Results: All surveyed subjects were females who were aged mostly between 26-30 years (49.46%) , with a mean age of 29.66±5.28 years. These nurses were mainly from the Department of Infection (28.99%) and Spine Surgery (21.56%) . There were significant differences in the back, shoulders/arms, neck, work rhythm, and work pressure scores between different nursing procedures ( F =16.613, 5.884, 3.431, 3.222, and 5.085, respectively; P <0.05) . Patient-turning nursing procedures resulted in high to intermediate physical load in nurses. Procedures with high to low level of WMSDs exposure were patient turning (72.69%) , bed linen changing (67.15%) , patient transfer (65.82%) , and chest physiotherapy (58.34%) . In particular, patient turning was considered as very high-risk procedure, whereas others were considered as high-risk procedures. Conclusion: Patient-turning nursing procedures result in high ergonomic load in the operators. Therefore, more focus should be placed on the ergonomics of the caretakers and nurses.
1983-08-01
procedures and results for this project on the Biomechanics of Load Carrying Behavior. The work was formulated and directed by Drs. Carolyn K. Bensel...The first of these loads had a mass of approximately 26 kg, including all clothing and equipment worn or carried by the subject, and served as a...rifle, which weighed 3.17 kg, and the ALICE load carrying system. The pack, which weighed 1.10 kg, was loaded with Army clothing and equipment items
Work load and individual factors affecting work ability among aging municipal employees.
Tuomi, K; Eskelinen, L; Toikkanen, J; Jarvinen, E; Ilmarinen, J; Klockars, M
1991-01-01
The effects of work stressors, individual characteristics, symptoms, and diseases on work ability were studied among 4255 municipal employees. Work ability was assessed by a work ability index in two cross-sectional inquiries, one in 1981 and the other in 1985. The most impairing for work ability were mental symptoms and musculoskeletal disease. Among the work stressors, high physical demands at work, poor physical work environment, and lack of freedom were associated with impaired work ability. Muscular work, disturbing temperatures at the workplace, and lack of freedom particularly affected employees with disease, whereas poor work postures and role conflicts at work were particularly injurious for healthy employees. The worst situation was observed when a worker with many symptoms and disease was exposed to many different work stressors. Life satisfaction, sitting work posture, a good basic education, and physical exercise during leisure time were associated with good work ability.
Example-Based Learning in Heuristic Domains: A Cognitive Load Theory Account
ERIC Educational Resources Information Center
Renkl, Alexander; Hilbert, Tatjana; Schworm, Silke
2009-01-01
One classical instructional effect of cognitive load theory (CLT) is the worked-example effect. Although the vast majority of studies have focused on well-structured and algorithmic sub-domains of mathematics or physics, more recent studies have also analyzed learning with examples from complex domains in which only heuristic solution strategies…
Physical-chemical processes of diamond grinding
NASA Astrophysics Data System (ADS)
Lobanov, D. V.; Arhipov, P. V.; Yanyushkin, A. S.; Skeeba, V. Yu
2017-10-01
The article focuses on the relevance of the research into the problem of diamond abrasive metal-bonded tool performance loss with a view to enhancing the effectiveness of high-strength materials finishing processing. The article presents the results of theoretical and empirical studies of loading layer formation on the surface of diamond wheels during processing high-strength materials. The theoretical part deals with the physical and chemical processes at the contact area of the diamond wheel and work surface with the viewpoint of the electrochemical potentials equilibrium state. We defined dependencies for calculating the loading layer dimensions. The practical part of work centers on various electron-microscopic, spectral and X-ray diffraction studies of the metal-bonded wheel samples during diamond grinding. The analysis of the research results revealed the composition and structure of the loading layer. The validity of the theoretical data is confirmed by sufficient convergence of the calculated values with the results of empirical research. In order to reduce the intensity of loading and improve the cutting properties of metal-bonded diamond abrasive tools, it is recommended to use combined methods for more efficient processing of high-strength materials.
Factors associated with inadequate work ability among women in the clothing industry.
Augusto, Viviane Gontijo; Sampaio, Rosana Ferreira; Ferreira, Fabiane Ribeiro; Kirkwood, Renata Noce; César, Cibele Comini
2015-01-01
Work ability depends on a balance between individual resources and work demands. This study evaluated factors that are associated with inadequate work ability among workers in the clothing industry. We conducted a cross-sectional observational study of 306 workers in 40 small and medium-sized enterprises. We assessed work ability, individual resources, physical and psychosocial demands, and aspects of life outside work using a binary logistic regression model with hierarchical data entry. The mean work ability was 42.5 (SD=3.5); when adjusted for age, only 11% of the workers showed inadequate work ability. The final model revealed that smoking, high isometric physical load, and poor physical environmental conditions were the most significant predictors of inadequate work ability. Good working conditions and worker education must be implemented to eliminate factors that can be changed and that have a negative impact on work ability. These initiatives include anti-smoking measures, improved postures at work, and better physical environmental conditions.
The farrier's work environment.
Löfqvist, Lotta; Pinzke, Stefan
2012-01-01
The horse industry in Sweden has rapidly expanded in recent years. This increasing number of horses implies a greater need for more farriers. Shoeing a horse is hard physical work, and includes awkward work postures and repetitive movements. It is well known that hard physical work increases the risk of injuries and musculoskeletal problems. The risk is especially high for musculoskeletal disorders when certain movements are constantly repeated. Heavy or repeated unilateral loads lead to considerable stress on the muscles, which can lead to rupture and fatigue that can cause long term problems. A case study showed that farriers worked 75% of their work time with their backs in bent positions (often more than 70 degrees). Farriers are also exposed to risk factors in their physical environment like dust, noise and poor lighting. Risk of kicks and bites, eye injuries and burns are other factors that make their work environment hazardous. There are only a few studies available that have documented the farriers' working environment and these are not of recent date. A US study from 1984 described kicks and bites from horses, metal splinters in the eyes, heat exhaustion and problematic postures to be perceived as the greatest risks in their work. The back, knees and wrists were the most exposed body regions. There is a need for more current and in-depth studies investigating the farriers' working conditions in order to gain more knowledge of their health and work environment. The aim of the present study is to investigate the physical health and work environment of farriers. The investigation will use questionnaires, work load measurements and workplace analysis. The results will serve as a base for improvements concerning the design of the workplace, equipment, tools and aids as well as supplying recommendations about physical exercise and the correct work technique, etc. The results are planned to be incorporated in the education of farriers.
Roskoden, Frederick Charles; Krüger, Janine; Vogt, Lena Johanna; Gärtner, Simone; Hannich, Hans Joachim; Steveling, Antje; Lerch, Markus M; Aghdassi, Ali A
2017-01-01
Among health care personnel working regular hours or rotating shifts can affect parameters of general health and nutrition. We have investigated physical activity, sleep quality, metabolic activity and stress levels in health care workers from both groups. We prospectively recruited 46 volunteer participants from the workforce of a University Medical Department of which 23 worked in rotating shifts (all nursing) and 21 non-shift regular hours (10 nursing, 13 clerical staff). All were investigated over 7 days by multisensory accelerometer (SenseWear Bodymedia® armband) and kept a detailed food diary. Physical activity and resting energy expenditure (REE) were measured in metabolic equivalents of task (METs). Quality of sleep was assessed as Pittsburgh Sleeping Quality Index and stress load using the Trier Inventory for Chronic Stress questionnaire (TICS). No significant differences were found for overall physical activity, steps per minute, time of exceeding the 3 METs level or sleep quality. A significant difference for physical activity during working hours was found between shift-workers vs. non-shift-workers (p<0.01) and for shift-working nurses (median = 2.1 METs SE = 0.1) vs. non-shift-working clerical personnel (median = 1.5 METs SE = 0.07, p<0.05). Non-shift-working nurses had a significantly lower REE than the other groups (p<0.05). The proportion of fat in the diet was significantly higher (p<0.05) in the office worker group (median = 42% SE = 1.2) whereas shift-working nurses consumed significantly more carbohydrates (median = 46% SE = 1.4) than clerical staff (median = 41% SE = 1.7). Stress assessment by TICS confirmed a significantly higher level of social overload in the shift working group (p<0.05). In this prospective cohort study shift-working had no influence on overall physical activity. Lower physical activity during working hours appears to be compensated for during off-hours. Differences in nutritional habits and stress load warrant larger scale trials to determine the effect on implicit health-associated conditions.
Vogt, Lena Johanna; Gärtner, Simone; Hannich, Hans Joachim; Steveling, Antje; Lerch, Markus M.
2017-01-01
Background Among health care personnel working regular hours or rotating shifts can affect parameters of general health and nutrition. We have investigated physical activity, sleep quality, metabolic activity and stress levels in health care workers from both groups. Methods We prospectively recruited 46 volunteer participants from the workforce of a University Medical Department of which 23 worked in rotating shifts (all nursing) and 21 non-shift regular hours (10 nursing, 13 clerical staff). All were investigated over 7 days by multisensory accelerometer (SenseWear Bodymedia® armband) and kept a detailed food diary. Physical activity and resting energy expenditure (REE) were measured in metabolic equivalents of task (METs). Quality of sleep was assessed as Pittsburgh Sleeping Quality Index and stress load using the Trier Inventory for Chronic Stress questionnaire (TICS). Results No significant differences were found for overall physical activity, steps per minute, time of exceeding the 3 METs level or sleep quality. A significant difference for physical activity during working hours was found between shift-workers vs. non-shift-workers (p<0.01) and for shift-working nurses (median = 2.1 METs SE = 0.1) vs. non-shift-working clerical personnel (median = 1.5 METs SE = 0.07, p<0.05). Non-shift-working nurses had a significantly lower REE than the other groups (p<0.05). The proportion of fat in the diet was significantly higher (p<0.05) in the office worker group (median = 42% SE = 1.2) whereas shift-working nurses consumed significantly more carbohydrates (median = 46% SE = 1.4) than clerical staff (median = 41% SE = 1.7). Stress assessment by TICS confirmed a significantly higher level of social overload in the shift working group (p<0.05). Conclusion In this prospective cohort study shift-working had no influence on overall physical activity. Lower physical activity during working hours appears to be compensated for during off-hours. Differences in nutritional habits and stress load warrant larger scale trials to determine the effect on implicit health-associated conditions. PMID:28081231
[Heart rate and energy expenditure during extravehicular activity in different time of day].
Stepanova, S I; Katuntsev, V P; Osipov, Iu Iu; Galichiĭ, V A
2013-01-01
The article discusses the comparative heart rate (HR) characteristics associated with day and night extravehicular activities (EVA). HR was commonly higher in the night but not in the daytime. Presumably, the reason is psychological and physiological challenges of the night work on the background of natural performance decrement. These circumstances could lead to elevation of psychic tension and, consequently, increase of heartbeats to a greater extent as compared with daytime EVA. According to the correlation analysis data, the pattern of HR relation to physical loads evaluated by energy expenditure in the daytime was other than at night, i.e. it was positive unlike the nighttime correlation. We cannot exclude it that in the daytime increase in cardiac output (CO) in response to physical work was largely due to increase in HR, whereas it was stroke volume that dominated during night work; at least, it could support CO fully in the periods of low loading.
Dwivedi, Dipankar; Mohanty, Binayak P.; Lesikar, Bruce J.
2013-01-01
Microbes have been identified as a major contaminant of water resources. Escherichia coli (E. coli) is a commonly used indicator organism. It is well recognized that the fate of E. coli in surface water systems is governed by multiple physical, chemical, and biological factors. The aim of this work is to provide insight into the physical, chemical, and biological factors along with their interactions that are critical in the estimation of E. coli loads in surface streams. There are various models to predict E. coli loads in streams, but they tend to be system or site specific or overly complex without enhancing our understanding of these factors. Hence, based on available data, a Bayesian Neural Network (BNN) is presented for estimating E. coli loads based on physical, chemical, and biological factors in streams. The BNN has the dual advantage of overcoming the absence of quality data (with regards to consistency in data) and determination of mechanistic model parameters by employing a probabilistic framework. This study evaluates whether the BNN model can be an effective alternative tool to mechanistic models for E. coli loads estimation in streams. For this purpose, a comparison with a traditional model (LOADEST, USGS) is conducted. The models are compared for estimated E. coli loads based on available water quality data in Plum Creek, Texas. All the model efficiency measures suggest that overall E. coli loads estimations by the BNN model are better than the E. coli loads estimations by the LOADEST model on all the three occasions (three-fold cross validation). Thirteen factors were used for estimating E. coli loads with the exhaustive feature selection technique, which indicated that six of thirteen factors are important for estimating E. coli loads. Physical factors included temperature and dissolved oxygen; chemical factors include phosphate and ammonia; biological factors include suspended solids and chlorophyll. The results highlight that the LOADEST model estimates E. coli loads better in the smaller ranges, whereas the BNN model estimates E. coli loads better in the higher ranges. Hence, the BNN model can be used to design targeted monitoring programs and implement regulatory standards through TMDL programs. PMID:24511166
Attarchi, Mirsaeed; Ghaffari, Mostafa; Abdi, Alireza; Mirzamohammadi, Elham; Seyedmehdi, Seyed Mohammad; Rahimpour, Farzaneh; Fazlalizadeh, Maryam; Mohammadi, Saber
2014-04-20
Early leaving of workplace by work forces is one of the fundamental problems worldwide. Maintenance and enhancement of employees work ability are important for raising productivity. This study investigated the relationship between work ability index and physical working conditions and was carried out in 2013 on 641 workers at a manufacturing plant in Tehran. Work ability was assessed by the questionnaire of work ability index and the participants were classified into four work ability groups of poor, moderate, good, and excellent. Physical working conditions were evaluated by the MUSIC-Norrtalje questionnaire and the participants were classified into two groups with proper and poor physical working conditions. The mean score of work ability questionnaire was 42.40; and 2.5% (16 persons), 9.2% (59 persons), 38.2% (245 persons), and 50.1% (321 persons) of the participants were in poor, moderate, good, and excellent work ability groups, respectively. The mean score of physical working conditions questionnaire was 20.06. The results of logistic regression analysis showed that even after adjusting the confounding variables, a significant correlation existed between work ability and physical working conditions (p < 0.05). According to the results of this study, there may be a correlation between physical working conditions such as awkward postures, repetitive movements, load lifting, exposure to whole body vibration and so on with work ability. Therefore it seems that enhancement of the quality of physical working conditions may increase work ability.
Attarchi, Mirsaeed; Ghaffari, Mostafa; Abdi, Alireza; Mirzamohammadi, Elham; Seyedmehdi, Seyed Mohammad; Rahimpour, Farzaneh; Fazlalizadeh, Maryam; Mohammadi, Saber
2014-01-01
Early leaving of workplace by work forces is one of the fundamental problems worldwide. Maintenance and enhancement of employees work ability are important for raising productivity. This study investigated the relationship between work ability index and physical working conditions and was carried out in 2013 on 641 workers at a manufacturing plant in Tehran. Work ability was assessed by the questionnaire of work ability index and the participants were classified into four work ability groups of poor, moderate, good, and excellent. Physical working conditions were evaluated by the MUSIC-Norrtalje questionnaire and the participants were classified into two groups with proper and poor physical working conditions. The mean score of work ability questionnaire was 42.40; and 2.5% (16 persons), 9.2% (59 persons), 38.2% (245 persons), and 50.1% (321 persons) of the participants were in poor, moderate, good, and excellent work ability groups, respectively. The mean score of physical working conditions questionnaire was 20.06. The results of logistic regression analysis showed that even after adjusting the confounding variables, a significant correlation existed between work ability and physical working conditions (p<0.05). According to the results of this study, there may be a correlation between physical working conditions such as awkward postures, repetitive movements, load lifting, exposure to whole body vibration and so on with work ability. Therefore it seems that enhancement of the quality of physical working conditions may increase work ability. PMID:24999133
NASA Technical Reports Server (NTRS)
Glezer, G. A.; Charyyev, M.; Zilbert, N. L.
1980-01-01
Age effect on gas exchange was studied in the recumbent and orthostatic positions and under physical load. In the case of the older age group and for normal as compared with hypersthenic persons, oxygen consumption during rest and during moderate physical overload diminishes. When the vertical position is assumed oxygen consumption in persons of various age groups is distinctly increased, particularly in the elderly group. There is a reduction in the amount of oxygen consumption, oxygen pulse, recovery coefficient, and work efficiency under moderate overload. In persons over 50, physical labor induces a large oxygen requirement and a sharp rise in the level of lactic acid and the blood's lactate/pyruvate ratio. No distinct difference was noted in the amount of oxygen consumed during rest and during physical overload in men and women of the same physical development and age.
NASA Astrophysics Data System (ADS)
Haslam, Carolyn Yvonne; Hamilton, Richard Joseph
2010-09-01
This study investigated the effects of integrated illustrations on understanding instructions for practical work in science. Ninety-six secondary school students who were unfamiliar with the target content knowledge and practical equipment took part. The students were divided into two conditions: (1) modified instructions containing integrated text and illustrations, and (2) conventional instructions containing text only. Modified instructions produced significantly higher levels of performance on task, lower time to completion and perceived cognitive load and task difficulty, higher relative efficiency score, and higher post-test scores than the conventional instructions. When learners are inexperienced and the information is complex, the results suggest that physically integrating mutually referring sources of information reduces cognitive load, and therefore makes practical work instructions easier to understand.
The effects of work-related and individual factors on the Work Ability Index: a systematic review.
van den Berg, T I J; Elders, L A M; de Zwart, B C H; Burdorf, A
2009-04-01
This paper systematically reviews the scientific literature on the effects of individual and work-related factors on the Work Ability Index (WAI). Studies on work ability published from 1985 to 2006 were identified through a structured search in PubMed, and Web of Science. Studies were included if the WAI was used as measure of work ability and if quantitative information was presented on determinants of work ability. In total, 20 studies were included with 14 cross-sectional studies and six longitudinal studies. Factors associated with poor work ability, as defined by WAI, were lack of leisure-time vigorous physical activity, poor musculoskeletal capacity, older age, obesity, high mental work demands, lack of autonomy, poor physical work environment, and high physical work load. The WAI is associated with individual characteristics, lifestyle, demands at work, and physical condition. This multifactorial nature of work ability should be taken into account in health promotion programmes aimed at maintaining and promoting the participation of the labour force and improvement of the performance at work.
Prefrontal Hemodynamics of Physical Activity and Environmental Complexity During Cognitive Work.
McKendrick, Ryan; Mehta, Ranjana; Ayaz, Hasan; Scheldrup, Melissa; Parasuraman, Raja
2017-02-01
The aim of this study was to assess performance and cognitive states during cognitive work in the presence of physical work and in natural settings. Authors of previous studies have examined the interaction between cognitive and physical work, finding performance decrements in working memory. Neuroimaging has revealed increases and decreases in prefrontal oxygenated hemoglobin during the interaction of cognitive and physical work. The effect of environment on cognitive-physical dual tasking has not been previously considered. Thirteen participants were monitored with wireless functional near-infrared spectroscopy (fNIRS) as they performed an auditory 1-back task while sitting, walking indoors, and walking outdoors. Relative to sitting and walking indoors, auditory working memory performance declined when participants were walking outdoors. Sitting during the auditory 1-back task increased oxygenated hemoglobin and decreased deoxygenated hemoglobin in bilateral prefrontal cortex. Walking reduced the total hemoglobin available to bilateral prefrontal cortex. An increase in environmental complexity reduced oxygenated hemoglobin and increased deoxygenated hemoglobin in bilateral prefrontal cortex. Wireless fNIRS is capable of monitoring cognitive states in naturalistic environments. Selective attention and physical work compete with executive processing. During executive processing loading of selective attention and physical work results in deactivation of bilateral prefrontal cortex and degraded working memory performance, indicating that physical work and concomitant selective attention may supersede executive processing in the distribution of mental resources. This research informs decision-making procedures in work where working memory, physical activity, and attention interact. Where working memory is paramount, precautions should be taken to eliminate competition from physical work and selective attention.
Nelson, C Beau; Zivin, Kara; Walters, Heather; Ganoczy, Dara; MacDermid Wadsworth, Shelley; Valenstein, Marcia
2015-12-01
Employment is a vital part of the postdeployment return to civilian life. This study investigated factors associated with employment-related outcomes (employment status, self-reported work performance, and self-reported work satisfaction) among National Guard members returning from Operation Enduring Freedom, Operation Iraqi Freedom, or Operation New Dawn deployments. The sample consisted of 1,151 National Guard service members who had returned from overseas deployments approximately six months earlier. Bivariate and multivariable analyses were performed to examine associations between predictors and employment-related outcome variables. Higher-risk alcohol use was associated with reduced odds of being employed as well as with lower ratings of work satisfaction, whereas psychiatric symptom load was associated with lower self-reported work performance and work satisfaction ratings. Perceived social resources were associated with higher self-reported work performance and work satisfaction, whereas better physical functioning was associated with better self-reported work performance. Policy makers and clinicians may need to consider and assess alcohol use among unemployed National Guard members. They may also need to consider psychiatric symptom load and physical functioning among employed service members who perceive poor work performance and have low work satisfaction. Further research is needed on causal links between these predictors and employment outcomes.
Science 101: Q--What Is the Physics behind Simple Machines?
ERIC Educational Resources Information Center
Robertson, Bill
2013-01-01
Bill Robertson thinks that questioning the physics behind simple machines is a great idea because when he encounters the subject of simple machines in textbooks, activities, and classrooms, he seldom encounters, a scientific explanation of how they work. Instead, what one often sees is a discussion of load, effort, fulcrum, actual mechanical…
NASA Technical Reports Server (NTRS)
Gates, Thomas S.; Veazie, David R.; Brinson, L. Catherine
1996-01-01
Experimental and analytical methods were used to investigate the similarities and differences of the effects of physical aging on creep compliance of IM7/K3B composite loaded in tension and compression. Two matrix dominated loading modes, shear and transverse, were investigated for two load cases, tension and compression. The tests, run over a range of sub-glass transition temperatures, provided material constants, material master curves and aging related parameters. Comparing results from the short-term data indicated that although trends in the data with respect to aging time and aging temperature are similar, differences exist due to load direction and mode. The analytical model used for predicting long-term behavior using short-term data as input worked equally as well for the tension or compression loaded cases. Comparison of the loading modes indicated that the predictive model provided more accurate long term predictions for the shear mode as compared to the transverse mode. Parametric studies showed the usefulness of the predictive model as a tool for investigating long-term performance and compliance acceleration due to temperature.
Load carriage, human performance, and employment standards.
Taylor, Nigel A S; Peoples, Gregory E; Petersen, Stewart R
2016-06-01
The focus of this review is on the physiological considerations necessary for developing employment standards within occupations that have a heavy reliance on load carriage. Employees within military, fire fighting, law enforcement, and search and rescue occupations regularly work with heavy loads. For example, soldiers often carry loads >50 kg, whilst structural firefighters wear 20-25 kg of protective clothing and equipment, in addition to carrying external loads. It has long been known that heavy loads modify gait, mobility, metabolic rate, and efficiency, while concurrently elevating the risk of muscle fatigue and injury. In addition, load carriage often occurs within environmentally stressful conditions, with protective ensembles adding to the thermal burden of the workplace. Indeed, physiological strain relates not just to the mass and dimensions of carried objects, but to how those loads are positioned on and around the body. Yet heavy loads must be borne by men and women of varying body size, and with the expectation that operational capability will not be impinged. This presents a recruitment conundrum. How do employers identify capable and injury-resistant individuals while simultaneously avoiding discriminatory selection practices? In this communication, the relevant metabolic, cardiopulmonary, and thermoregulatory consequences of loaded work are reviewed, along with concomitant impediments to physical endurance and mobility. Also emphasised is the importance of including occupation-specific clothing, protective equipment, and loads during work-performance testing. Finally, recommendations are presented for how to address these issues when evaluating readiness for duty.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Weiland, R.H.; Dingman, J.C.; Cronin, D.B.
1997-09-01
New data are reported on the heat capacity of CO{sub 2}-loaded, aqueous solutions of monoethanolamine (MEA), diethanolamine (DEA), N-methyldiethanolamine (MDEA), and aqueous MDEA-based blends with MEA and DEA. The work reported here was motivated by the need to quantify the effect of acid gas loading on the important physical properties of gas-sweetening solvents.
Exoskeletons for industrial application and their potential effects on physical work load.
de Looze, Michiel P; Bosch, Tim; Krause, Frank; Stadler, Konrad S; O'Sullivan, Leonard W
2016-05-01
The aim of this review was to provide an overview of assistive exoskeletons that have specifically been developed for industrial purposes and to assess the potential effect of these exoskeletons on reduction of physical loading on the body. The search resulted in 40 papers describing 26 different industrial exoskeletons, of which 19 were active (actuated) and 7 were passive (non-actuated). For 13 exoskeletons, the effect on physical loading has been evaluated, mainly in terms of muscle activity. All passive exoskeletons retrieved were aimed to support the low back. Ten-forty per cent reductions in back muscle activity during dynamic lifting and static holding have been reported. Both lower body, trunk and upper body regions could benefit from active exoskeletons. Muscle activity reductions up to 80% have been reported as an effect of active exoskeletons. Exoskeletons have the potential to considerably reduce the underlying factors associated with work-related musculoskeletal injury. Practitioner Summary: Worldwide, a significant interest in industrial exoskeletons does exist, but a lack of specific safety standards and several technical issues hinder mainstay practical use of exoskeletons in industry. Specific issues include discomfort (for passive and active exoskeletons), weight of device, alignment with human anatomy and kinematics, and detection of human intention to enable smooth movement (for active exoskeletons).
Load Balancing Scientific Applications
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pearce, Olga Tkachyshyn
2014-12-01
The largest supercomputers have millions of independent processors, and concurrency levels are rapidly increasing. For ideal efficiency, developers of the simulations that run on these machines must ensure that computational work is evenly balanced among processors. Assigning work evenly is challenging because many large modern parallel codes simulate behavior of physical systems that evolve over time, and their workloads change over time. Furthermore, the cost of imbalanced load increases with scale because most large-scale scientific simulations today use a Single Program Multiple Data (SPMD) parallel programming model, and an increasing number of processors will wait for the slowest one atmore » the synchronization points. To address load imbalance, many large-scale parallel applications use dynamic load balance algorithms to redistribute work evenly. The research objective of this dissertation is to develop methods to decide when and how to load balance the application, and to balance it effectively and affordably. We measure and evaluate the computational load of the application, and develop strategies to decide when and how to correct the imbalance. Depending on the simulation, a fast, local load balance algorithm may be suitable, or a more sophisticated and expensive algorithm may be required. We developed a model for comparison of load balance algorithms for a specific state of the simulation that enables the selection of a balancing algorithm that will minimize overall runtime.« less
Kaila-Kangas, Leena; Arokoski, Jari; Impivaara, Olli; Viikari-Juntura, Eira; Leino-Arjas, Päivi; Luukkonen, Ritva; Heliövaara, Markku
2011-10-01
We reviewed work histories of manual handling of loads >20 kg in relation to hip osteoarthritis by age, exposure and work participation. A nationally representative sample of 3110 Finnish men and 3446 women aged 30-97 was recruited. Diagnosis of hip osteoarthritis was based on standardised clinical examination by trained physicians. Previous exposure to physically loading work was evaluated through interviews. Logistic regression was used to estimate associations between work factors and hip osteoarthritis. 1.9% of men and 2.1% of women had hip osteoarthritis. Almost half the men and a quarter of the women had recurrently handled heavy loads at work. Subjects who had manually handled loads >20 kg had a 1.8-fold increased risk of hip osteoarthritis compared to non-exposed references, when age, body mass index, traumatic fractures and smoking were accounted for. Results were similar for men (OR 2.0; 95% CI 1.0 to 4.0) and women (1.8; 1.1 to 2.8). In a sub-analysis of subjects with hip replacement, the OR was 1.7 (1.0 to 2.9). Risk increased first after 12 years' exposure: among men it was 2.2 (0.8 to 5.9) for 13-24 years' exposure, and 2.3 (1.2 to 4.3) for >24 years' exposure. Among women it was 3.8 (1.7 to 8.1) for 13-24 years' exposure. Work participation among men aged <60 years with hip osteoarthritis was 20% lower compared with subjects without osteoarthritis. A work history of manual handling of loads >20 kg showed a strong association with hip osteoarthritis in all age groups except the youngest.
Heavy Physical Work: Cardiovascular Load in Male Construction Workers
Lunde, Lars-Kristian; Koch, Markus; Veiersted, Kaj Bo; Moen, Gunn-Helen; Wærsted, Morten; Knardahl, Stein
2016-01-01
This study aimed to elucidate cardiovascular loads (CVL) in construction workers during work and leisure by relative heart rate (RHR) over several days. Furthermore, we sought to evaluate the level of CVL in relation to individual factors, work ability, musculoskeletal pain and subjective general health. From a group of 255 construction workers responding to the baseline questionnaire, the CVL during work and leisure time was determined by recording RHR in 42 workers over 3–4 days. Almost 60% of the workday was spent below 20% RHR. The mean RHR during work for all participants was 16% RHR, with large differences between professions. On average, the 42 workers spent 14% of the workday at a RHR above 33%, and four subjects (10%) had a mean RHR above 33% during work. Eight (19%) of the participants had a mean length of their workday exceeding calculated maximal acceptable work time. Seven persons (17%) experienced on average one or more episode(s) of 5 min or more continuously above 33% RHR. The cardiovascular load at work was significantly associated with age and V˙O2max, but not with work ability, musculoskeletal pain or subjective general health. PMID:27023574
Electronic Energy Meter Based on a Tunnel Magnetoresistive Effect (TMR) Current Sensor.
Vidal, Enrique García; Muñoz, Diego Ramírez; Arias, Sergio Iván Ravelo; Moreno, Jaime Sánchez; Cardoso, Susana; Ferreira, Ricardo; Freitas, Paulo
2017-09-26
In the present work, the design and microfabrication of a tunneling magnetoresistance (TMR) electrical current sensor is presented. After its physical and electrical characterization, a wattmeter is developed to determine the active power delivered to a load from the AC 50/60 Hz mains line. Experimental results are shown up to 1000 W of power load. A relative uncertainty of less than 1.5% with resistive load and less than 1% with capacitive load was obtained. The described application is an example of how TMR sensing technology can play a relevant role in the management and control of electrical energy.
Electronic Energy Meter Based on a Tunnel Magnetoresistive Effect (TMR) Current Sensor
García Vidal, Enrique; Ravelo Arias, Sergio Iván; Sánchez Moreno, Jaime; Ferreira, Ricardo; Freitas, Paulo
2017-01-01
In the present work, the design and microfabrication of a tunneling magnetoresistance (TMR) electrical current sensor is presented. After its physical and electrical characterization, a wattmeter is developed to determine the active power delivered to a load from the AC 50/60 Hz mains line. Experimental results are shown up to 1000 W of power load. A relative uncertainty of less than 1.5% with resistive load and less than 1% with capacitive load was obtained. The described application is an example of how TMR sensing technology can play a relevant role in the management and control of electrical energy. PMID:28954425
[Multifactorial method for assessing the physical work capacity of mice].
Dubovik, B V; Bogomazov, S D
1987-01-01
Based on the swimming test according to Kiplinger, in experiments on (CBA X C57BL)F1 mice there were elaborated criteria for animal performance evaluation in the process of repeated swimming of a standard distance thus measuring power, volume of work and rate of the fatigue development in relative units. From the study of effects of sydnocarb, bemethyl and phenazepam on various parameters of physical performance of mice a conclusion was made that the proposed method provides a more informative evaluation of the pharmacological effect on physical performance of animals as compared to the methods based on the record of time of performing the load.
Work organization and health among immigrant women: Latina manual workers in North Carolina.
Arcury, Thomas A; Grzywacz, Joseph G; Chen, Haiying; Mora, Dana C; Quandt, Sara A
2014-12-01
We sought to describe work organization attributes for employed immigrant Latinas and determine associations of work organization with physical health, mental health, and health-related quality of life. We conducted a cross-sectional survey with 319 employed Latinas in western North Carolina (2009-2011). Measures included job demands (heavy load, awkward posture, psychological demand), decision latitude (skill variety, job control), support (supervisor control, safety climate), musculoskeletal symptoms, mental health (depressive symptoms), and mental (MCS) and physical component score (PCS) health-related quality of life. Three fifths reported musculoskeletal symptoms. Mean scores for depression, MCS, and PCS were 6.2 (SE = 0.2), 38.3 (SE = 0.5), and 42.8 (SE = 0.3), respectively. Greater job demands (heavy load, awkward posture, greater psychological demand) were associated with more musculoskeletal and depressive symptoms and worse MCS. Less decision latitude (lower skill variety, job control) was associated with more musculoskeletal and depressive symptoms. Greater support (supervisor's power and safety climate) was associated with fewer depressive symptoms and better MCS. Work organization should be considered to improve occupational health of vulnerable women workers. Additional research should delineate the links between work organization and health among vulnerable workers.
Minimizing masses in explosively driven two-shockwave physics applications
NASA Astrophysics Data System (ADS)
Buttler, William; Cherne, Frank; Furlanetto, Michael; Payton, Jeremy; Stone, Joseph; Tabaka, Leonard; Vincent, Samuel
2015-06-01
We have experimentally investigated different two-shockwave high-explosives (HE) physics package designs to maximize the variability of the second shockwave peak stress, while minimizing the total HE load of the physics tool. A critical requirement is to also have a large radial diameter of the second shockwave to maintain its value as an HE driven two-shockwave drive. We have previously shown that we could vary the peak-stress of the second-shockwave with a 76 mm diameter HE lens driving different composite boosters of PBX 9501 and TNT. Here we report on our results with a 56- and 50-mm diameter HE lens driving Baritol. The results indicate that the 56-mm diameter HE lens works well, as does the Baritol, giving total HE loads of about 250 mg TNT equivalent explosives.
Is the working capacity of Liberian industrial workers increased by regular malaria prophylaxis?
Pehrson, P O; Björkman, A; Brohult, J; Jorfeldt, L; Lundbergh, P; Rombo, L; Willcox, M; Bengtsson, E
1984-10-01
In a study of the impact of malaria prophylaxis upon the physical working capacity of Liberian industrial workers, two groups of men, one with and the other without malaria prophylaxis, were compared over a period of one year. At the beginning and at the end of the study, the haemoglobin concentration, haematocrit, blood volume and physical performance--measured by bicycle ergometry and expressed as work load at heart rate 170--were compared. No significant differences were found, either within or between the two groups. Routinely distributed malaria prophylaxis thus seems to be of little importance with respect to working capacity in this type of community, where malaria is meso-endemic.
Neutron assay in mixed radiation fields with a 6Li-loaded plastic scintillator
NASA Astrophysics Data System (ADS)
Balmer, M. J. I.; Gamage, K. A. A.; Taylor, G. C.
2015-08-01
A novel technique for assay of thermal and fast neutrons in a 6Li-loaded plastic scintillator is presented. Existing capture-gated thermal neutron detection techniques were evaluated with the 6Li-loaded plastic scintillator studied in this work. Using simulations and experimental work, shortcomings in its performance were highlighted. As a result, it was proposed that by separating the combined fast and thermal neutron events from gamma events, using established pulse shape discrimination techniques, the thermal neutron events could then be assayed. Experiments were conducted at the National Physical Laboratory, Teddington, performing neutron assays with seven different neutron fields using the proposed technique. For each field, thermal and fast neutron content was estimated and were shown to corroborate with the seven synthesised fields.
Mette, Janika; Mache, Stefanie; Harth, Volker; Preisser, Alexandra M
2018-01-01
Objectives To assess the physical strains of employees in the German offshore wind industry, according to job type and phase of the wind farm (under construction or operation). Design Web-based cross-sectional survey. Setting Offshore wind farm companies operating within the German exclusive economic zone. Participants Male workers with regular offshore commitments and at least 28 days spent offshore in the past year (n=268). Outcome measures Physical strains (eg, climbing, noise, working overhead, with twisted upper body or in confined spaces, vibration, heavy lifting, humidity, odours). Results The most frequently mentioned physical strain was ’climbing’ with 63.8% of the respondents reporting to be always or frequently confronted with climbing and ascending stairs during offshore work. Work as a technician was associated with a greater exposition to noise, vibrations, humidity, cold, heat, chemical substances, lifting/carrying heavy loads, transport of equipment, working in non-ergonomic positions and in cramped spaces, as well as climbing. Indeed, statistical analyses showed that, after adjusting for phase of the wind farm, age, nationality, offshore experience, work schedule and type of shift, compared with non-technicians, working as a technician was associated with more frequently lifting/carrying of heavy loads (OR 2.58, 95% CI 1.58 to 4.23), transport of equipment (OR 2.06 95% CI 1.27 to 3.33), working with a twisted upper body (OR 2.85 95% CI 1.74 to 4.69), working overhead (OR 2.77 95% CI 1.67 to 4.58) and climbing (OR 2.30 95% CI 1.40 to 3.77). Working in wind farms under construction was strongly associated with increased and decreased exposure to humidity (OR 2.32 95% CI 1.38 to 3.92) and poor air quality (OR 0.58 95% CI 0.35 to 0.95), respectively. Conclusions Workers on offshore wind farms constitute a heterogeneous group, including a wide variety of occupations. The degree of exposure to detrimental physical strains varies depending on the type of job. Technicians are more exposed to ergonomic challenges than other offshore workers. PMID:29602849
El-Salamouni, Noha S; Farid, Ragwa M; El-Kamel, Amal H; El-Gamal, Safaa S
2015-12-30
Nanoparticulate delivery systems have recently been under consideration for topical ophthalmic drug delivery. Brimonidine base-loaded solid lipid nanoparticles and nanostructured lipid carrier formulations were prepared using glyceryl monostearate as solid lipid and were evaluated for their physical stability following sterilization by autoclaving at 121°C for 15min. The objective of this work was to evaluate the effect of autoclaving on the physical appearance, particle size, polydispersity index, zeta potential, entrapment efficiency and particle morphology of the prepared formulations, compared to non-autoclaved ones. Results showed that, autoclaving at 121°C for 15min allowed the production of physically stable formulations in nanometric range, below 500nm suitable for ophthalmic application. Moreover, the autoclaved samples appeared to be superior to non-autoclaved ones, due to their increased zeta potential values, indicating a better physical stability. As well as, increased amount of brimonidine base entrapped in the tested formulations. Copyright © 2015 Elsevier B.V. All rights reserved.
Psychosocial Factors and Musculoskeletal Pain Among Rural Hand-woven Carpet Weavers in Iran
Chaman, Reza; Aliyari, Roqayeh; Sadeghian, Farideh; Vatani Shoaa, Javad; Masoudi, Mahmood; Zahedi, Shiva; Bakhshi, Mohammad A.
2015-01-01
Background Musculoskeletal pain (MSP) is a common and disabling problem among carpet weavers and is linked to physical and psychosocial factors of work. This study aimed to determine the prevalence of MSP, its psychosocial risk factors, and association of pain in each pair of anatomical sites among carpet weavers. Methods A cross-sectional study was performed among 546 hand-woven carpet weavers in rural small-scale workshops of Iran. Data were collected by using parts of a standardized CUPID (Cultural and Psychosocial Influences on Disability) questionnaire focused on MSP in 10 body sites, including the low-back, neck, both right and left shoulders, elbows, wrists/hands, individual, physical and psychosocial risk factors. Statistical analysis was performed applying logistic regression models. Results Prevalence of MSP in at least one body site was 51.7% over the past month. The most common sites were low back and right shoulder pain 27.4% and 20.1%, respectively. A significant difference was found between the mean number of painful anatomical sites and the level of education, age, physical loading at work, time pressure, lack of support, and job dissatisfaction. In pairwise comparisons, strongest association was found between pain in each bilateral anatomical site (odds ratio = 11.6–35.3; p < 0.001). Conclusion In home-based workshops of carpet weaving, psychosocial factors and physical loading were associated with MSP. This finding is consistent with studies conducted among other jobs. Considering the preventive programs, the same amount of attention should be paid to psychosocial risk factors and physical loading. Also, further longitudinal studies are needed to investigate the relationship of psychological factors. PMID:26106511
Faber, Anne; Strøyer, Jesper; Hjortskov, Nis; Schibye, Bente
2010-01-01
To investigate changes of physical performance during long working hours and extended workweeks among construction workers with temporary accommodation in camps. Nineteen construction workers with 12-h workdays and extended workweeks participated. Physical performance in the morning and evening of the second and eleventh workdays was tested by endurance, ability to react to a sudden load, flexibility of the back, handgrip strength and sub-maximal HR during a bicycle test. HR was registered throughout two separate workdays. HR during each of the two separate workdays corresponded to a relative workload of 25%. Sub-maximal HR was lower, reaction time faster and handgrip strength higher in the end of each test day. In the end of the work period, sub-maximal HR was lower, reaction time faster and sitting balance was better. No trends of decreased physical performance were found after a workday or a work period.
Jakobsen, Markus Due; Sundstrup, Emil; Persson, Roger; Andersen, Christoffer H; Andersen, Lars L
2014-02-01
To investigate associations between perceived exertion and objectively assessed muscular and cardiovascular load during a full working day among workers with manual lifting tasks. A total of 159 men and 41 women from 14 workplaces with manual lifting tasks participated. Participants reported perceived exertion (BORG-CR10) at midday and after work. Surface electromyography of the thigh, lower back and neck muscles were normalized to isometric voluntary contractions (MVC) to express relative muscle load during the day. Cardiovascular load was measured with electrocardiography and calculated as the average percentage of the heart rate reserve capacity (((heart rate during work - resting heart rate) / (maximum heart rate - resting heart rate)) * 100) during the day. Using linear regression, significant but weak associations (β < 0.23) were observed between perceived exertion and (1) high muscle activity (>60% of MVC) of the neck muscles and (2) inactivity (<1% of MVC) of the thigh muscles and (3) cardiovascular load, respectively. Using logistic regression, perceived exertion ≥4 (high exertion), referencing <4 (low-to-moderate exertion), was related to high activity of the trapezius muscle [OR 18 (95% CI 2-143)], i.e., the odds for experiencing high exertion during work increased 18-fold for each percentage increase in time above 60% MVC. During a full working day among blue-collar workers with lifting tasks, high neck muscle activity increases the odds for experiencing high perceived physical exertion. Perceived exertion of at least 4 on the BORG CR10 scale appears to be a good indicator that high muscular loading occurs.
Direct measurements of anode/cathode gap plasma in cylindrically imploding loads on the Z machine
NASA Astrophysics Data System (ADS)
Porwitzky, A.; Dolan, D. H.; Martin, M. R.; Laity, G.; Lemke, R. W.; Mattsson, T. R.
2018-06-01
By deploying a photon Doppler velocimetry based plasma diagnostic, we have directly observed low density plasma in the load anode/cathode gap of cylindrically converging pulsed power targets. The arrival of this plasma is temporally correlated with gross current loss and subtle power flow differences between the anode and the cathode. The density is in the range where Hall terms in the electromagnetic equations are relevant, but this physics is lacking in the magnetohydrodynamics codes commonly used to design, analyze, and optimize pulsed power experiments. The present work presents evidence of the importance of physics beyond traditional resistive magnetohydrodynamics for the design of pulsed power targets and drivers.
Relationships of cognitive load on eating and weight-related behaviors of young adults.
Byrd-Bredbenner, Carol; Quick, Virginia; Koenings, Mallory; Martin-Biggers, Jennifer; Kattelmann, Kendra K
2016-04-01
Little is known about the relationship between weight-related behaviors and cognitive load (working memory available to complete mental activities like those required for planning meals, selecting foods, and other health-related decisions). Thus, the purpose of this study was to explore associations between cognitive load and eating behaviors, physical activity, body mass index (BMI), and waist circumference of college students. College students (n=1018) from 13 institutions completed an online survey assessing eating behaviors (e.g., routine and compensatory restraint, emotional eating, and fruit/vegetable intake), stress level, and physical activity level. BMI and waist circumference were measured by trained researchers. A cognitive load score was derived from stress level, time pressure/income needs, race and nationality. High cognitive load participants (n=425) were significantly (P<0.05) more likely to be female, older, and further along in school than those with low cognitive loads (n=593). Compared to low cognitive load participants, high cognitive load participants were significantly more likely to eat <5 cups of fruits/vegetables/day, have greater routine and compensatory restraint, and greater susceptibility to eating in response to external cues and emotional eating. Both males and females with high cognitive load scores had a non-significant trend toward higher BMIs, waist circumferences, and drinking more alcohol than low cognitive load counterparts. In conclusion, cognitive load may be an important contributor to health behaviors. Understanding how cognitive load may affect eating and other weight-related behaviors could potentially lead to improvements in the effectiveness of obesity prevention and intervention programs. Copyright © 2015 Elsevier Ltd. All rights reserved.
Dynamic water exercise in individuals with late poliomyelitis.
Willén, C; Sunnerhagen, K S; Grimby, G
2001-01-01
To evaluate the specific effects of general dynamic water exercise in individuals with late effects of poliomyelitis. Before-after tests. A university hospital department. Twenty-eight individuals with late effects of polio, 15 assigned to the training group (TG) and 13 to the control group (CG). The TG completed a 40-minute general fitness training session in warm water twice weekly. Assessment instruments included the bicycle ergometer test, isokinetic muscle strength, a 30-meter walk indoors, Berg balance scale, a pain drawing, a visual analog scale, the Physical Activity Scale for the Elderly, and the Nottingham Health Profile (NHP). Peak load, peak work load, peak oxygen uptake, peak heart rate (HR), muscle function in knee extensors and flexors, and pain dimension of the NHP. The average training period was 5 months; compliance was 75% (range, 55-98). No negative effects were seen. The exercise did not influence the peak work load, peak oxygen uptake, or muscle function in knee extensors compared with the controls. However, a decreased HR at the same individual work load was seen, as well as a significantly lower distress in the dimension pain of the NHP. Qualitative aspects such as increased well-being, pain relief, and increased physical fitness were reported. A program of nonswimming dynamic exercises in heated water has a positive impact on individuals with late effects of polio, with a decreased HR at exercise, less pain, and a subjective positive experience. The program was well tolerated (no adverse effects were reported) and can be recommended for this group of individuals.
Miranda, Helena; Gore, Rebecca J; Boyer, Jon; Nobrega, Suzanne; Punnett, Laura
2015-01-01
Many worksite health promotion programs ignore the potential influence of working conditions on unhealthy behaviors. A study of nursing home employees (56% nursing aides) utilized a standardized questionnaire. We analyzed the cross-sectional associations between workplace stressors and obesity, cigarette smoking, and physical inactivity. Of 1506 respondents, 20% reported exposure to three or more workplace stressors (physical or organizational), such as lifting heavy loads, low decision latitude, low coworker support, regular night work, and physical assault. For each outcome, the prevalence ratio was between 1.5 and 2 for respondents with four or five job stressors. Individuals under age 40 had stronger associations between workplace stressors and smoking and obesity. Workplace stressors were strongly associated with smoking, obesity, and physical inactivity, even among the lowest-status workers. Current working conditions affected younger workers more than older workers. Although this study is cross-sectional, it has other strengths, including the broad range of work stressors studied. Strenuous physical work and psychosocial strain are common among low-wage workers such as nursing home aides. Workplace health promotion programs may be more effective if they include measures to reduce stressful work environment features, so that working conditions support rather than interfere with employee health.
Miranda, Helena; Gore, Rebecca J.; Boyer, Jon; Nobrega, Suzanne; Punnett, Laura
2015-01-01
Background. Many worksite health promotion programs ignore the potential influence of working conditions on unhealthy behaviors. Methods. A study of nursing home employees (56% nursing aides) utilized a standardized questionnaire. We analyzed the cross-sectional associations between workplace stressors and obesity, cigarette smoking, and physical inactivity. Results. Of 1506 respondents, 20% reported exposure to three or more workplace stressors (physical or organizational), such as lifting heavy loads, low decision latitude, low coworker support, regular night work, and physical assault. For each outcome, the prevalence ratio was between 1.5 and 2 for respondents with four or five job stressors. Individuals under age 40 had stronger associations between workplace stressors and smoking and obesity. Conclusions. Workplace stressors were strongly associated with smoking, obesity, and physical inactivity, even among the lowest-status workers. Current working conditions affected younger workers more than older workers. Although this study is cross-sectional, it has other strengths, including the broad range of work stressors studied. Strenuous physical work and psychosocial strain are common among low-wage workers such as nursing home aides. Workplace health promotion programs may be more effective if they include measures to reduce stressful work environment features, so that working conditions support rather than interfere with employee health. PMID:26380373
Fischer, Steven L; Sinden, Kathryn E; MacPhee, Renee S
2017-11-01
Public safety related occupations including police, fire and military commonly apply physical employment standard (PES) to facilitate job matching, an approach to evaluate if candidates demonstrate acceptable physical capabilities as required to perform the job safely and effectively. In Canada, paramedics remain as one of the few public safety occupations without an evidence-based, validated PES. The purpose of this study was to document and describe the physical demands of paramedic work and to identify the most physically demanding tasks. These outcomes are essential to inform the design and development of an evidence-based PES for the paramedic sector. Physical demands of paramedic work were documented and described using a direct observation-based task analysis technique. Five paramedic's were trained to document the physical demands of their work, then applied their training to observe more than 90 calls over the course of 20 full 12-h work shifts. Physical demands data were then listed in a survey, administered service-wide, where 155 frontline paramedics identified critically demanding tasks and rank-ordered physical demands from not physically demanding to very strongly demanding. Critically important and physically demanding tasks were identified such as: transferring a patient; loading or unloading a stretcher in to or out of the ambulance; performing CPR; and, raising and lowering a stretcher. It is important that a paramedic-based PES evaluate a candidate's physical capabilities to perform the critical and physically demanding tasks identified in this study. Copyright © 2017 Elsevier Ltd. All rights reserved.
1994-06-03
transport , the effects of technology, terrain and weather, and physical conditioning. Load, Soidier’s Load, Rucksack, Physical Conditioning, Combat Load...Fighting Load, Sustainment Load, Approach March Load, Fear, Fatigue, Risk, Training, Transport , Techn-logy UNCLASSIFIED UNCLASSIFIED UNCLASSIFIED I .1 THE...standards, myths of peacetime training, the nature of the soldier, lack of transport , the effects of technology, terrain and weather, and physical
NASA Technical Reports Server (NTRS)
Pandolf, Kent B.; Stroschein, Leander A.; Gonzalez, Richard R.; Sawka, Michael N.
1994-01-01
This institute has developed a comprehensive USARIEM heat strain model for predicting physiological responses and soldier performance in the heat which has been programmed for use by hand-held calculators, personal computers, and incorporated into the development of a heat strain decision aid. This model deals directly with five major inputs: the clothing worn, the physical work intensity, the state of heat acclimation, the ambient environment (air temperature, relative humidity, wind speed, and solar load), and the accepted heat casualty level. In addition to predicting rectal temperature, heart rate, and sweat loss given the above inputs, our model predicts the expected physical work/rest cycle, the maximum safe physical work time, the estimated recovery time from maximal physical work, and the drinking water requirements associated with each of these situations. This model provides heat injury risk management guidance based on thermal strain predictions from the user specified environmental conditions, soldier characteristics, clothing worn, and the physical work intensity. If heat transfer values for space operations' clothing are known, NASA can use this prediction model to help avoid undue heat strain in astronauts during space flight.
A physical workload index to evaluate a safe resident handling program for nursing home personnel.
Kurowski, Alicia; Buchholz, Bryan; Punnett, Laura
2014-06-01
The aim of this study was to obtain a comprehensive analysis of the physical workload of clinical staff in long-term care facilities, before and after a safe resident handling program (SRHP). Ergonomic exposures of health care workers include manual handling of patients and many non-neutral postures. A comprehensive assessment requires the integration of loads from these varied exposures into a single metric. The Postures, Activities, Tools, and Handling observational protocol, customized for health care, was used for direct observations of ergonomic exposures in clinical jobs at 12 nursing homes before the SRHP and 3, 12, 24, and 36 months afterward. Average compressive forces on the spine were estimated for observed combinations of body postures and manual handling and then weighted by frequencies of observed time for the combination. These values were summed to obtain a biomechanical index for nursing assistants and nurses across observation periods. The physical workload index (PWI) was much higher for nursing assistants than for nurses and decreased more after 3 years (-24% versus -2.5%). Specifically during resident handling, the PWI for nursing assistants decreased by 41% of baseline value. Spinal loading was higher for nursing assistants than for nurses in long-term care centers. Both job groups experienced reductions in physical loading from the SRHP, especially the nursing assistants and especially while resident handling. The PWI facilitates a comprehensive investigation of physical loading from both manual handling and non-neutral postures. It can be used in any work setting to identify high-risk tasks and determine whether reductions in one exposure are offset by increases in another.
Dutch Musculoskeletal Questionnaire: description and basic qualities.
Hildebrandt, V H; Bongers, P M; van Dijk, F J; Kemper, H C; Dul, J
2001-10-10
A questionnaire ('Dutch Musculoskeletal Questionnaire', DMQ) for the analysis of musculoskeletal workload and associated potential hazardous working conditions as well as musculoskeletal symptoms in worker populations is described and its qualities are explored using a database of 1575 workers in various occupations who completed the questionnaire. The 63 questions on musculoskeletal workload and associated potentially hazardous working conditions can be categorized into seven indices (force, dynamic and static load, repetitive load, climatic factors, vibration and ergonomic environmental factors). Together with four separate questions on standing, sitting, walking and uncomfortable postures, the indices constitute a brief overview of the main findings on musculoskeletal workload and associated potentially hazardous working conditions. Homogeneity of the indices is satisfactory. The divergent validity of the indices is fair when compared with an index of psychosocial working conditions and discomfort during exposure to physical loads. Worker groups with contrasting musculoskeletal loads can be differentiated on the basis of the indices and other factors. With respect to the concurrent validity, it appears that most indices and factors show significant associations with low back and/or neck-shoulder symptoms. This questionnaire can be used as a simple and quick inventory for occupational health services to identify worker groups in which a more thorough ergonomic analysis is indicated.
Work production of quantum rotor engines
NASA Astrophysics Data System (ADS)
Seah, Stella; Nimmrichter, Stefan; Scarani, Valerio
2018-04-01
We study the mechanical performance of quantum rotor heat engines in terms of common notions of work using two prototypical models: a mill driven by the heat flow from a hot to a cold mode, and a piston driven by the alternate heating and cooling of a single working mode. We evaluate the extractable work in terms of ergotropy, the kinetic energy associated to net directed rotation, as well as the intrinsic work based on the exerted torque under autonomous operation, and we compare them to the energy output for the case of an external dissipative load and for externally driven engine cycles. Our results connect work definitions from both physical and information-theoretical perspectives. In particular, we find that apart from signatures of angular momentum quantization, the ergotropy is consistent with the intuitive notion of work in the form of net directed motion. It also agrees with the energy output to an external load or agent under optimal conditions. This sets forth a consistent thermodynamical description of rotating quantum motors, flywheels, and clocks.
Subjective evaluation of physical and mental workload interactions across different muscle groups.
Mehta, Ranjana K; Agnew, Michael J
2015-01-01
Both physical and mental demands, and their interactions, have been shown to increase biomechanical loading and physiological reactivity as well as impair task performance. Because these interactions have shown to be muscle-dependent, the aim of this study was to determine the sensitivity of the NASA Task Load Index (NASA TLX) and Ratings of Perceived Exertion (RPE) to evaluate physical and mental workload during muscle-specific tasks. Twenty-four participants performed upper extremity and low back exertions at three physical workload levels in the absence and presence of a mental stressor. Outcome measures included RPE and NASA TLX (six sub-scales) ratings. The findings indicate that while both RPEs and NASA TLX ratings were sensitive to muscle-specific changes in physical demand, only an additional mental stressor and its interaction with either physical demand or muscle groups influenced the effort sub-scale and overall workload scores of the NASA TLX. While additional investigations in actual work settings are warranted, the NASA TLX shows promise in evaluating perceived workload that is sensitive not only to physical and mental demands but also sensitive in determining workload for tasks that employ different muscle groups.
Merchaoui, Irtyah; Bouzgarrou, Lamia; Mnasri, Ahlem; Mghanem, Mounir; Akrout, Mohamed; Malchaire, Jacques; Chaari, Neila
2017-01-01
This study has been performed to determine the influence of rotating shift work on physical working capacity of Tunisian nurses and to design recommendations to managers so that they implement effective preventive measures. It is a cross-sectional design using a standardized questionnaire and many physical capacity tests on a representative sample of 1181 nurses and nursing assistants from two university hospital centers of the school of Medicine of Monastir located in the Tunisian Sahel. 293 participants have been recruited by stratified random sampling according to gender and departments. Maximum Grip strength, 30s sit-to-stand test, one leg test, Fingertip-to-Floor test, Saltsa test and peak expiratory flow were used to assess physical capacity. Work ability was assessed through the workability index. Mental and physical loads were heavily perceived in shift healthcare workers (p=0.01; p=0.02). The maximum grip force was stronger in rotating shift work nurses (p=0.0001). Regarding to the seniority subgroups in each kind of work schedule, the Body Mass Index was increasing with seniority in both schedules. All the physical tests, were better in less-than-ten-year groups. Peak Flow and grip strength were significantly better in less-than-ten-year seniority in shift work group. There is a need to improve the design of the existing shift systems and to reduce as much as possible shift schedule as well as to avoid shift schedule for over-10-year-seniority nurses.
Multi-physics optimization of three-dimensional microvascular polymeric components
NASA Astrophysics Data System (ADS)
Aragón, Alejandro M.; Saksena, Rajat; Kozola, Brian D.; Geubelle, Philippe H.; Christensen, Kenneth T.; White, Scott R.
2013-01-01
This work discusses the computational design of microvascular polymeric materials, which aim at mimicking the behavior found in some living organisms that contain a vascular system. The optimization of the topology of the embedded three-dimensional microvascular network is carried out by coupling a multi-objective constrained genetic algorithm with a finite-element based physics solver, the latter validated through experiments. The optimization is carried out on multiple conflicting objective functions, namely the void volume fraction left by the network, the energy required to drive the fluid through the network and the maximum temperature when the material is subjected to thermal loads. The methodology presented in this work results in a viable alternative for the multi-physics optimization of these materials for active-cooling applications.
The use of subjective rating of exertion in Ergonomics.
Capodaglio, P
2002-01-01
In Ergonomics, the use of psychophysical methods for subjectively evaluating work tasks and determining acceptable loads has become more common. Daily activities at the work site are studied not only with physiological methods but also with perceptual estimation and production methods. The psychophysical methods are of special interest in field studies of short-term work tasks for which valid physiological measurements are difficult to obtain. The perceived exertion, difficulty and fatigue that a person experiences in a certain work situation is an important sign of a real or objective load. Measurement of the physical load with physiological parameters is not sufficient since it does not take into consideration the particular difficulty of the performance or the capacity of the individual. It is often difficult from technical and biomechanical analyses to understand the seriousness of a difficulty that a person experiences. Physiological determinations give important information, but they may be insufficient due to the technical problems in obtaining relevant but simple measurements for short-term activities or activities involving special movement patterns. Perceptual estimations using Borg's scales give important information because the severity of a task's difficulty depends on the individual doing the work. Observation is the most simple and used means to assess job demands. Other evaluations integrating observation are the followings: indirect estimation of energy expenditure based on prediction equations or direct measurement of oxygen consumption; measurements of forces, angles and biomechanical parameters; measurements of physiological and neurophysiological parameters during tasks. It is recommended that determinations of performances of occupational activities assess rating of perceived exertion and integrate these measurements of intensity levels with those of activity's type, duration and frequency. A better estimate of the degree of physical activity of individuals thus can be obtained.
Factors contributing to work related low back pain among personal care workers in old age.
Yeung, Simon S
2012-01-01
This study aims to preliminary explore the work related and individual factors that contributed to the occurrence of low back pain (LBP) that affected work activities of Personal Care Workers (PCWs). A cross-sectional study was conducted to 36 PCWs in an old age home of Hong Kong. The study is divided into three parts: 1) a questionnaire to document the workload exposure factors and the musculoskeletal symptoms survey of the PCWs, 2) work posture evaluation; and 3) an evaluation of the physical fitness and lifting capacity of the PCWs. Univariate analyses were used to explore the risk factors associated with LBP that affected work activities. The results indicated that individual physical profile and lifting capacities did not contribute to occurrence of low back pain at work. For the work demand factors, the perceived physical demands in lifting and lowering heavy objects, awkward sustain neck and back postures, loading on the back, and perceived effort of cleaning task contributed to the occurrence of LBP. For the physical environment factors, thermal stress and improper ventilation were associated with the occurrence of LBP cases. For the individual factor, LBP cases were associated with workers' self perceived muscular effort, and perceived risk of mental illness in response to work requirements.
Velasco Garrido, Marcial; Mette, Janika; Mache, Stefanie; Harth, Volker; Preisser, Alexandra M
2018-03-30
To assess the physical strains of employees in the German offshore wind industry, according to job type and phase of the wind farm (under construction or operation). Web-based cross-sectional survey. Offshore wind farm companies operating within the German exclusive economic zone. Male workers with regular offshore commitments and at least 28 days spent offshore in the past year (n=268). Physical strains (eg, climbing, noise, working overhead, with twisted upper body or in confined spaces, vibration, heavy lifting, humidity, odours). The most frequently mentioned physical strain was 'climbing' with 63.8% of the respondents reporting to be always or frequently confronted with climbing and ascending stairs during offshore work. Work as a technician was associated with a greater exposition to noise, vibrations, humidity, cold, heat, chemical substances, lifting/carrying heavy loads, transport of equipment, working in non-ergonomic positions and in cramped spaces, as well as climbing.Indeed, statistical analyses showed that, after adjusting for phase of the wind farm, age, nationality, offshore experience, work schedule and type of shift, compared with non-technicians, working as a technician was associated with more frequently lifting/carrying of heavy loads (OR 2.58, 95% CI 1.58 to 4.23), transport of equipment (OR 2.06 95% CI 1.27 to 3.33), working with a twisted upper body (OR 2.85 95% CI 1.74 to 4.69), working overhead (OR 2.77 95% CI 1.67 to 4.58) and climbing (OR 2.30 95% CI 1.40 to 3.77). Working in wind farms under construction was strongly associated with increased and decreased exposure to humidity (OR 2.32 95% CI 1.38 to 3.92) and poor air quality (OR 0.58 95% CI 0.35 to 0.95), respectively. Workers on offshore wind farms constitute a heterogeneous group, including a wide variety of occupations. The degree of exposure to detrimental physical strains varies depending on the type of job. Technicians are more exposed to ergonomic challenges than other offshore workers. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
Prediction of physical workload in reduced gravity environments
NASA Technical Reports Server (NTRS)
Goldberg, Joseph H.
1987-01-01
The background, development, and application of a methodology to predict human energy expenditure and physical workload in low gravity environments, such as a Lunar or Martian base, is described. Based on a validated model to predict energy expenditures in Earth-based industrial jobs, the model relies on an elemental analysis of the proposed job. Because the job itself need not physically exist, many alternative job designs may be compared in their physical workload. The feasibility of using the model for prediction of low gravity work was evaluated by lowering body and load weights, while maintaining basal energy expenditure. Comparison of model results was made both with simulated low gravity energy expenditure studies and with reported Apollo 14 Lunar EVA expenditure. Prediction accuracy was very good for walking and for cart pulling on slopes less than 15 deg, but the model underpredicted the most difficult work conditions. This model was applied to example core sampling and facility construction jobs, as presently conceptualized for a Lunar or Martian base. Resultant energy expenditures and suggested work-rest cycles were well within the range of moderate work difficulty. Future model development requirements were also discussed.
Associations of work-family conflicts with food habits and physical activity.
Roos, Eva; Sarlio-Lähteenkorva, Sirpa; Lallukka, Tea; Lahelma, Eero
2007-03-01
This study examines the relationship between family-work conflicts with food habits and physical activity, and whether the relationship is dependent on family structure and work-related factors. Cross-sectional postal surveys were carried out in 2001 and 2002 among employees of the City of Helsinki, Finland, aged 40-60 years (n = 5346, response rate 66%; for women 70% and for men 60%). Dependent variables in logistic regression analyses were nationally recommended food habits and physical activity. Independent variables were work-family conflicts and family-work conflicts. Covariates included age, marital status, number of children, occupational class, working hours, time travelling to work, and physical and mental work load. Women reporting strong work-family conflicts were more likely to follow recommended food habits (odds ratio (OR) and 95% confidence intervals 1.49 (1.19-1.86)), but this relationship weakened when adjusting for work-related factors (OR 1.20 (0.93-1.55)). Women and men with strong family-work conflicts were less likely to report recommended food habits after adjusting for family structure and work-related factors (women OR 0.75 (0.61-0.92), men OR 0.57 (0.34-0.96)). Women and men with strong work-family conflicts were less likely to follow the recommended amount of physical activity (women OR 0.76 (0.60-0.96), men OR 0.54 (0.34-0.87)). Additionally, women with strong family-work conflicts were less likely to follow the recommended amount of physical activity (OR 0.77 (0.63-0.94)). Adjusting for family and work-related factors did not affect these associations. Conflicts between paid work and family life are likely to constitute barriers for a physically active lifestyle and possibly also for healthy food habits. Improving the balance between work and family may provide a route for promoting health-related behaviours.
Rostamabadi, Akbar; Mazloumi, Adel; Rahimi Foroushani, Abbas
2014-01-01
This study aimed to determine the Work Ability Index (WAI) and examine the influence of health dimensions and demographic variables on the work ability of Iranian farmers working in small farm enterprises. A cross-sectional study was conducted among 294 male farmers. The WAI and SF-36 questionnaires were used to determine work ability and health status. The effect of demographics variables on the work ability index was investigated with the independent samples t-test and one-way ANOVA. Also, multiple linear regression analysis was used to test the association between the mean WAI score and the SF-36 scales. The mean WAI score was 35.1 (SD=10.6). One-way ANOVA revealed a significant relationship between the mean WAI and age. Multiple linear regression analysis showed that work ability was more influenced by physical scales of the health dimensions, such as physical function, role-physical, and general health, whereas a lower association was found for mental scales such as mental health. The average WAI was at a moderate work ability level for the sample population of farmers in this study. Based on the WAI guidelines, improvement of work ability and identification of factors affecting it should be considered a priority in interventional programs. Given the influence of health dimensions on WAI, any intervention program for preservation and promotion of work ability among the studied farmers should be based on balancing and optimizing the physical and psychosocial work environments, with a special focus on reducing physical work load.(J Occup Health 2014; 56: 478-484).
[Child labor in a marketplace in Bogotá].
Briceño, Leonardo; Pinzón, Angela María
2005-01-01
Child labor in marketplaces has not been sufficiently studied. It is present even in developed countries and it has been associated with problems in the physical, psychological, emotional and social development of children. This paper aims at determining the number of children working in the largest marketplace in the country and the risk factors to which they are exposed. Children working in the marketplace were counted and classified by gender and occupation. Working places were analyzed under Fine's professional risk plan. 376 children were found, 318 boys and 58 girls. 30% were carrying loads, 42% were selling merchandise, and 28% were doing minor jobs or accompanying relatives. The risk factors related with their personal security have the greatest danger level. They are followed by the ergonomic, psychosocial and biological factors. The risk factors affecting children's health the most in the short term are those related to personal security. They include vehicle traffic, inadequate materials storage that can be dangerous, and the physical burden that they have to suffer. According to the professional risk factors plan, this is a dangerous job for children. Child labor in marketplaces shall be regulated and the carrying of heavy loads prohibited.
Energy expenditure and activity among Hadza hunter-gatherers.
Pontzer, Herman; Raichlen, David A; Wood, Brian M; Emery Thompson, Melissa; Racette, Susan B; Mabulla, Audax Z P; Marlowe, Frank W
2015-01-01
Studies of total energy expenditure, (TEE; kcal/day) among traditional populations have challenged current models relating habitual physical activity to daily energy requirements. Here, we examine the relationship between physical activity and TEE among traditional Hadza hunter-gatherers living in northern Tanzania. Hadza adults were studied at two camps, with minimal intervention so as to monitor energy expenditure and activity during normal daily life. We measured daily walking distance and walking speed using wearable GPS units for 41 adults. For a subset of 30 adults, we measured TEE using doubly labeled water, three indices of work load (foraging return rate, maternal status, and number of dependent children), and urinary biomarkers of metabolic activity and stress (8-hydroxydeoxyguanosine, cortisol, and testosterone). Fat-free mass was the single strongest predictor of TEE among Hadza adults (r(2) = 0.66, P < 0.001). Hadza men used greater daily walking distances and faster walking speeds compared with that of Hadza women, but neither sex nor any measure of physical activity or work load were correlated with TEE in analyses controlling for fat-free mass. Compared with developed, industrial populations, Hadza adults had similar TEE but elevated levels of metabolic stress as measured by 8-hydroxydeoxyguanosine. Our results indicate that daily physical activity may not predict TEE within traditional hunter-gatherer populations like the Hadza. Instead, adults with high levels of habitual physical activity may adapt by reducing energy allocation to other physiological activity. © 2015 Wiley Periodicals, Inc.
Activation energy of the low-load NaCl transition from nanoindentation loading curves.
Kaupp, Gerd
2014-01-01
Access to activation energies E(a) of phase transitions is opened by unprecedented analyses of temperature dependent nanoindentation loading curves. It is based on kinks in linearized loading curves, with additional support by coincidence of kink and electrical conductivity of silicon loading curves. Physical properties of B1, B2, NaCl and further phases are discussed. The normalized low-load transition energy of NaCl (Wtrans/µN) increases with temperature and slightly decreases with load. Its semi-logarithmic plot versus T obtains activation energy E(a)/µN for calculation of the transition work for all interesting temperatures and pressures. Arrhenius-type activation energy (kJ/mol) is unavailable for indentation phase transitions. The E(a) per load normalization proves insensitive to creep-on-load, which excludes normalization to depth or volume for large temperature ranges. Such phase transition E(a)/µN is unprecedented material's property and will be of practical importance for the compatibility of composite materials under impact and further shearing interactions at elevated temperatures. © 2014 Wiley Periodicals, Inc.
Development of Vehicle Model Test for Road Loading Analysis of Sedan Model
NASA Astrophysics Data System (ADS)
Mohd Nor, M. K.; Noordin, A.; Ruzali, M. F. S.; Hussen, M. H.
2016-11-01
Simple Structural Surfaces (SSS) method is offered as a means of organizing the process for rationalizing the basic vehicle body structure load paths. The application of this simplified approach is highly beneficial in the design development of modern passenger car structure especially during the conceptual stage. In Malaysia, however, there is no real physical model of SSS available to gain considerable insight and understanding into the function of each major subassembly in the whole vehicle structures. Based on this motivation, a physical model of SSS for sedan model with the corresponding model vehicle tests of bending and torsion is proposed in this work. The proposed approach is relatively easy to understand as compared to Finite Element Method (FEM). The results show that the proposed vehicle model test is capable to show that satisfactory load paths can give a sufficient structural stiffness within the vehicle structure. It is clearly observed that the global bending stiffness reduce significantly when more panels are removed from a complete SSS model. It is identified that parcel shelf is an important subassembly to sustain bending load. The results also match with the theoretical hypothesis, as the stiffness of the structure in an open section condition is shown weak when subjected to torsion load compared to bending load. The proposed approach can potentially be integrated with FEM to speed up the design process of automotive vehicle.
Shoulder joint loading and posture during medicine cart pushing task.
Xu, Xu; Lin, Jia-Hua; Boyer, Jon
2013-01-01
Excessive physical loads and awkward shoulder postures during pushing and pulling are risk factors for shoulder pain. Pushing a medicine cart is a major component of a work shift for nurses and medical assistants in hospitals and other health care facilities. A laboratory experiment was conducted to examine the effects of common factors (e.g., lane congestion, cart load stability, floor surface friction) on shoulder joint moment and shoulder elevation angle of participants during cart pushing. Participants pushed a medicine cart on straight tracks and turning around right-angle corners. Peak shoulder joint moments reached 25.1 Nm, 20.3 Nm, and 26.8 Nm for initial, transition, and turning phases of the pushing tasks, indicating that shoulder joint loading while pushing a medical cart is comparable to levels previously reported from heavy manual activities encountered in industry (e.g., garbage collection). Also, except for user experience, all other main study factors, including congestion level, cart load stability, location of transition strip, shoulder tendency, surface friction, and handedness, significantly influenced shoulder joint moment and shoulder elevation angle. The findings provide a better understanding of shoulder exposures associated with medicine cart operations and may be helpful in designing and optimizing the physical environment where medicine carts are used.
Constitutive modeling of the dynamic-tensile-extrusion test of PTFE
NASA Astrophysics Data System (ADS)
Resnyansky, A. D.; Brown, E. N.; Trujillo, C. P.; Gray, G. T.
2017-01-01
Use of polymers in defense, aerospace and industrial applications under extreme loading conditions makes prediction of the behavior of these materials very important. Crucial to this is knowledge of the physical damage response in association with phase transformations during loading and the ability to predict this via multi-phase simulation accounting for thermodynamical non-equilibrium and strain rate sensitivity. The current work analyzes Dynamic-Tensile-Extrusion (Dyn-Ten-Ext) experiments on polytetrafluoroethylene (PTFE). In particular, the phase transition during loading and subsequent tension are analyzed using a two-phase rate sensitive material model implemented in the CTH hydrocode. The calculations are compared with experimental high-speed photography. Deformation patterns and their link with changing loading modes are analyzed numerically and correlated to the test observations. It is concluded that the phase transformation is not as critical to the response of PTFE under Dyn-Ten-Ext loading as it is during the Taylor rod impact testing.
Dale, Ann Marie; Miller, Kim; Gardner, Bethany T.; Hwang, Ching-Ting; Evanoff, Bradley; Welch, Laura
2015-01-01
Introduction Little is known about the transfer into the workplace of interventions designed to reduce the physical demands of sheet metal workers. Methods We reviewed videos from a case series of 15 sheet metal worksite assessments performed in 2007–2009 to score postures and physical loads, and to observe the use of recommended interventions to reduce physical exposures in sheet metal activities made by a NIOSH stakeholder meeting in 2002. Results Workers showed consistent use of material handling devices, but we observed few uses of recommended interventions to reduce exposures during overhead work. Workers spent large proportions of time in awkward shoulder elevation and low back rotation postures. Conclusions In addition to the development of new technologies and system designs, increased adoption of existing tools and practices could reduce time spent in awkward postures and other risks for musculoskeletal disorders in sheet metal work. PMID:26360196
Continuous Ultra-Thin MOS2 Films Grown by Low-Temperature Physical Vapor Deposition (Postprint)
2014-07-01
MoS2 target of 99.95% purity. The SiO2 and highly oriented pyrolitic graphite (HOPG) substrates were intro- duced via a vacuum load- lock and mounted on...im- mediately prior insertion into a sample vacuum load- lock . In this work, the samples were heated to 350 C and allowed to rotate at approximately...136805 (2010). 6H. Terrones, F. Lopez-Urias, and M. Terrones, Sci. Rep. 3(203), 1549 (2013). 7H. Li, Q. Zhang, C. C. R. Yap, B. K. Tay, T. H. T. Edwin
Work Physiology Evaluation of Laundry Workers
NASA Astrophysics Data System (ADS)
Sari, A. D.; Suryoputro, M. R.; Pramaningtyas, M. D.; Putra, P. S.; Maulidyawati, S. B.
2016-01-01
This study aimed to assess cardiovascular strain during laundry operations in terms of physical workload, based on heart rate changes and level of pain complaints. Researchers measured resting and working heart rates and calculated cardiovascular load (%CVL), cardiovascular strain (%CVS), reserve heart rate (%RHR), energy expenditure, oxygen consumption, and measure level of pain complain in 6 laundry workers using Nordic Body Map questionnaire (NBM). Based on the result of %CVL and %CVS, the work in laundry was classified as acceptable level. Similarly, a high-level category was recorded for %RHR in moderate of energy expenditure. However, there are very pain level complain for hand using NBM questionnaire. Thus, there is a need to redesign the work content of equipment used and keep the physical workload in acceptable level, as this will increase their productivity and reduce their health risk.
ERIC Educational Resources Information Center
Choi, Hwan-Hee; van Merriënboer, Jeroen J. G.; Paas, Fred
2014-01-01
Although the theoretical framework of cognitive load theory has acknowledged a role for the learning environment, the specific characteristics of the physical learning environment that could affect cognitive load have never been considered, neither theoretically nor empirically. In this article, we argue that the physical learning environment, and…
A physical interpretation of softening of pressure-sensitive and anisotropic materials
NASA Astrophysics Data System (ADS)
Hu, W.; Wang, Z. R.
2010-07-01
Several new dynamic models are proposed to explain the mechanical behaviour of softening of pressure-sensitive and anisotropic materials at a macroscopic level. If a pressure-sensitive material is loaded by a force and a variable pressure or an anisotropic material is subjected to a load with a changeable loading direction relative to the material frame, their stress-strain relationships become more complicated. Mechanical behaviours of these stress-strain relationships have to cover the feature concerning the change of pressure or loading direction, i.e. mechanical properties of pressure-sensitive material corresponding to different pressure state or anisotropic material relating to different loading direction will play an important role in deciding their stress-strain relationships. Such shift of material properties due to the variable pressure or loading history may significantly expand the traditional concept of the stability of material deformation, and the second order of plastic work being negative may be a response of stable plastic deformation, which is commonly called softening.
MICRO-U 70.1: Training Model of an Instructional Institution, Users Manual.
ERIC Educational Resources Information Center
Springer, Colby H.
MICRO-U is a student demand driven deterministic model. Student enrollment, by degree program, is used to develop an Instructional Work Load Matrix. Linear equations using Weekly Student Contact Hours (WSCH), Full Time Equivalent (FTE) students, FTE faculty, and number of disciplines determine library, central administration, and physical plant…
A Void Growth Failure Criterion Applied to Dynamically and Statically Loaded Thin Rings.
1980-06-01
the physical evidences, several other investigators (Berg, 1969, Nagpal , et al., 1972) working on the continuum aspect of failure, considered plastic...by the Growth of Holes", J. of Applied Mechanics, Vol. 35, 1968, p. 363. 23.) Nagpal , V., Mcclintock, F. A., Berg, C. A., and Subudhi, M., "Traction
The relationship between physical load and musculoskeletal complaints among Brazilian dentists.
Oliveira Dantas, Filipe Fernandes; de Lima, Kenio Costa
2015-03-01
The aim of the present study was to assess the relationship between physical load and musculoskeletal complaints in dentistry and to analyze the prevalence and severity of such complaints in nine anatomical regions using a cross-sectional study of 387 dentists from Natal, Brazil. The highest prevalence of complaints was related to the lower back (58.4%) and the lowest prevalence was found in the elbow (10.3%). In general, symptoms were classified as mild because they did not cause absence due to illness. Pain complaints were associated with the following characteristics: awkward posture at work; prolonged standing or sitting; strenuous position of the upper limbs; excessive tightening of the hands during clinical treatment; and the use of vibrating tools. The results of the present study suggest a high prevalence of musculoskeletal complaints in dentists that are significantly associated with variables related to their physical workload. Copyright © 2014 Elsevier Ltd and The Ergonomics Society. All rights reserved.
Simoneau, Guy G
2016-04-01
During the American Physical Therapy Association's Combined Sections Meeting in Anaheim, California in February 2016, JOSPT recognized the authors of the most outstanding research and clinical practice manuscripts published in JOSPT during the 2015 calendar year. The 2015 JOSPT Excellence in Research Award was presented to Björn Aasa, Lars Berglund, Peter Michaelson, and Ulrika Aasa for their paper titled "Individualized Low-Load Motor Control Exercises and Education Versus a High-Load Lifting Exercise and Education to Improve Activity, Pain Intensity, and Physical Performance in Patients With Low Back Pain: A Randomized Controlled Trial." The 2015 George J. Davies-James A. Gould Excellence in Clinical Inquiry Award was presented to Anne Benjaminse, Alli Gokeler, Bert Otten, Ariel V. Dowling, Avery Faigenbaum, Kevin R. Ford, Timothy E. Hewett, James A. Onate, and Gregory D. Myer for their work titled "Optimization of the Anterior Cruciate Ligament Injury Prevention Paradigm: Novel Feedback Techniques to Enhance Motor Learning and Reduce Injury Risk."
Review of ship slamming loads and responses
NASA Astrophysics Data System (ADS)
Wang, Shan; Guedes Soares, C.
2017-12-01
The paper presents an overview of studies of slamming on ship structures. This work focuses on the hull slamming, which is one of the most important types of slamming problems to be considered in the ship design process and the assessment of the ship safety. There are three main research aspects related to the hull slamming phenomenon, a) where and how often a slamming event occurs, b) slamming load prediction and c) structural response due to slamming loads. The approaches used in each aspect are reviewed and commented, together with the presentation of some typical results. The methodology, which combines the seakeeping analysis and slamming load prediction, is discussed for the global analysis of the hull slamming of a ship in waves. Some physical phenomena during the slamming event are discussed also. Recommendations for the future research and developments are made.
Working with horses: an OWAS work task analysis.
Löfqvist, L; Pinzke, S
2011-01-01
Most work in horse stables is performed manually in much the same way as a century ago. It is the least mechanized sector dealing with large animals. People working with horses are exposed to several types of risk for developing musculoskeletal problems, but the work tasks and workload have not been investigated in detail. The aim of this study was to estimate the postural load of the work tasks performed around horses to find those that were harmful and required measures to be taken to reduce physical strain. Altogether, 20 subjects (stable attendants and riding instructors) were video recorded while carrying out their work in the stable, and preparing and conducting riding lessons. The work was analyzed with the Ovako Working posture Analysis System (OWAS) to determine the postural load and to categorize the potential harmfulness of the work postures. Three work tasks involved about 50% of the work positions in the three OWAS categories (AC2 to AC4) where measures for improvement are needed: "mucking out" (50%), "bedding preparation" (48%), and "sweeping" (48%). These work tasks involved over 60% work postures where the back was bent, twisted, or both bent and twisted. Therefore, it is important to find preventive measures to reduce the workload, which could include improved tools, equipment, and work technique.
Physical Examination of the Wrist: Useful Provocative Maneuvers.
Kleinman, William B
2015-07-01
Chronic wrist pain resulting from partial interosseous ligament injury remains a diagnostic dilemma for many hand and orthopedic surgeons. Overuse of costly diagnostic studies including magnetic resonance imaging, computed tomography scans, and bone scans can be further frustrating to the clinician because of their inconsistent specificity and reliability in these cases. Physical diagnosis is an effective (and underused) means of establishing a working diagnosis of partial ligament injury to the wrist. Carefully performed provocative maneuvers can be used by the clinician to reproduce the precise character of a patient's problem, reliably establish a working diagnosis, and initiate a plan of treatment. Using precise physical examination techniques, the examiner introduces energy into the wrist in a manner that puts load on specific support ligaments of the carpus, leading to an accurate diagnosis. This article provides a broad spectrum of physical diagnostic tools to help the surgeon develop a working diagnosis of partial wrist ligament injuries in the face of chronic wrist pain and normal x-rays. Copyright © 2015 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.
PD-PK evaluation of freeze-dried atorvastatin calcium-loaded poly-ε-caprolactone nanoparticles.
Ahmed, Iman S; El-Hosary, Rania; Shalaby, Samia; Abd-Rabo, Marwa M; Elkhateeb, Dalia G; Nour, Samia
2016-05-17
In this work lyophilized poly-ε-caprolactone nanoparticles (NPs) loaded with atorvastatin calcium (AC) were developed in an attempt to improve the in-vivo performance of AC following oral administration. The individual and combined effects of several formulation variables were previously investigated using step-wise full factorial designs in order to produce optimized AC-NPs with predetermined characteristics including particle size, drug loading capacity, drug release profile and physical stability. Four optimized formulations were further subjected in this work to lyophilization to promote their long-term physical stability and were fully characterized. The pharmacodynamics (PD)/pharmacokinetics (PK) properties of two optimized freeze-dried AC-NPs formulations showing acceptable long-term stability were determined and compared to a marketed AC immediate release tablet (Lipitor(®)) in albino rats. PD results revealed that the two tested formulations were equally effective in reducing low density lipoproteins (LDL) and triglycerides (TG) levels when given in reduced doses compared to Lipitor(®) and showed no adverse effects. PK results, on the other hand, revealed that the two freeze-dried AC-NPs formulations were of significantly lower bioavailability compared to Lipitor(®). Taken together the PD and PK results demonstrate that the improved efficacy obtained at reduced doses from the freeze-dried AC-NPs could be due to increased concentration of AC in the liver rather than in the plasma. Copyright © 2016 Elsevier B.V. All rights reserved.
de M Guimarães, L B; Pessa, S L R; Biguelini, C
2012-01-01
This article presents a study on the evaluation of the workload imposed to workers of two sectors of a flexible packaging manufacturer that operates in three shifts. The workers are allocated in one of the shifts (morning, evening and night shifts) without evaluation of their chronotype and/or social needs. The Imprint sector has a more dynamic work, which is done only by man due to the effort demanded by handling loads. The work in the Cutting/Welding sector is static, done mainly by women. The results showed that the overall workload was the same in the Imprint and Cutting/Welding sectors, because physical effort for load handling is higher in the former but the latter involves high static load. The levels of urinary catecholamines and salivary cortisol were consistent with the workers biological clock showing that none of the workers changed his/her biological cycle to accommodate to the time of the shift schedule.
NASA Astrophysics Data System (ADS)
Moser, R. D.; Allison, P. G.; Chandler, M. Q.
2013-12-01
Little work has been done to study the fundamental material behaviors and failure mechanisms of cement-based materials including ordinary Portland cement concrete and ultra-high performance concretes (UHPCs) under high strain impact and penetration loads at lower length scales. These high strain rate loadings have many possible effects on UHPCs at the microscale and nanoscale, including alterations in the hydration state and bonding present in phases such as calcium silicate hydrate, in addition to fracture and debonding. In this work, the possible chemical and physical changes in UHPCs subjected to high strain rate impact and penetration loads were investigated using a novel technique wherein nanoindentation measurements were spatially correlated with images using scanning electron microscopy and chemical composition using energy dispersive x-ray microanalysis. Results indicate that impact degrades both the elastic modulus and indentation hardness of UHPCs, and in particular hydrated phases, with damage likely occurring due to microfracturing and debonding.
NASA Astrophysics Data System (ADS)
Sliva, Yekaterina
The purpose of this study was to introduce an instructional technique for teaching complex tasks in physics, test its effectiveness and efficiency, and understand cognitive processes taking place in learners' minds while they are exposed to this technique. The study was based primarily on cognitive load theory (CLT). CLT determines the amount of total cognitive load imposed on a learner by a learning task as combined intrinsic (invested in comprehending task complexity) and extraneous (wasteful) cognitive load. Working memory resources associated with intrinsic cognitive load are defined as germane resources caused by element interactivity that lead to learning, in contrast to extraneous working memory resources that are devoted to dealing with extraneous cognitive load. However, the amount of learner's working memory resources actually devoted to a task depends on how well the learner is engaged in the learning environment. Since total cognitive load has to stay within limits of working memory capacity, both extraneous and intrinsic cognitive load need to be reduced. In order for effective learning to occur, the use of germane cognitive resources should be maximized. In this study, the use of germane resources was maximized for two experimental groups by providing a learning environment that combined problem-solving procedure with prompts to self-explain with and without completion problems. The study tested three hypotheses and answered two research questions. The first hypothesis predicting that experimental treatments would reduce total cognitive load was not supported. The second hypothesis predicting that experimental treatments would increase performance was supported for the self-explanation group only. The third hypothesis that tested efficiency measure as adopted from Paas and van Merrienboer (1993) was not supported. As for the research question of whether the quality of self-explanations would change with time for the two experimental conditions, it was determined that time had a positive effect on such quality. The research question that investigated learners' attitudes towards the instructions revealed that experimental groups understood the main idea behind the suggested technique and positively reacted to it. The results of the study support the conclusions that (a) prompting learners to self-explain while independently solving problems can increase performance, especially on far transfer questions; (b) better performance is achieved in combination with increased mental effort; (c) self-explanations do not increase time on task; and (d) quality of self-explanations can be improved with time. Results based on the analyses of learners' attitudes further support that learners in the experimental groups understood the main idea behind the suggested techniques and positively reacted to them. The study also raised concern about application of efficiency formula for instructional conditions that increase both performance and mental effort in CLT. As a result, an alternative model was suggested to explain the relationship between performance and mental effort based on Yerkes-Dodson law (1908). Keywords: instructional design, cognitive load, complex tasks, problem-solving, self-explanation.
Biomechanical and psychosocial risk factors for low back pain at work.
Kerr, M S; Frank, J W; Shannon, H S; Norman, R W; Wells, R P; Neumann, W P; Bombardier, C
2001-01-01
OBJECTIVES: This study determined whether the physical and psychosocial demands of work are associated with low back pain. METHODS: A case-control approach was used. Case subjects (n = 137) reported a new episode of low back pain to their employer, a large automobile manufacturing complex. Control subjects were randomly selected from the study base as cases accrued (n = 179) or were matched to cases by exact job (n = 65). Individual, clinical, and psychosocial variables were assessed by interview. Physical demands were assessed with direct workplace measurements of subjects at their usual jobs. The analysis used multiple logistic regression adjusted for individual characteristics. RESULTS: Self-reported risk factors included a physically demanding job, a poor workplace social environment, inconsistency between job and education level, better job satisfaction, and better coworker support. Low job control showed a borderline association. Physical-measure risk factors included peak lumbar shear force, peak load handled, and cumulative lumbar disc compression. Low body mass index and prior low back pain compensation claims were the only significant individual characteristics. CONCLUSIONS: This study identified specific physical and psychosocial demands of work as independent risk factors for low back pain. PMID:11441733
Player Load, Acceleration, and Deceleration During Forty-Five Competitive Matches of Elite Soccer.
Dalen, Terje; Ingebrigtsen, Jørgen; Ettema, Gertjan; Hjelde, Geir Havard; Wisløff, Ulrik
2016-02-01
The use of time-motion analysis has advanced our understanding of position-specific work rate profiles and the physical requirements of soccer players. Still, many of the typical soccer activities can be neglected, as these systems only examine activities measured by distance and speed variables. This study used triaxial accelerometer and time-motion analysis to obtain new knowledge about elite soccer players' match load. Furthermore, we determined acceleration/deceleration profiles of elite soccer players and their contribution to the players' match load. The data set includes every domestic home game (n = 45) covering 3 full seasons (2009, 2010, and 2011) for the participating team (Rosenborg FC), and includes 8 central defenders (n = 68), 9 fullbacks (n = 83), 9 central midfielders (n = 70), 7 wide midfielders (n = 39), and 5 attackers (A, n = 50). A novel finding was that accelerations contributed to 7-10% of the total player load for all player positions, whereas decelerations contributed to 5-7%. Furthermore, the results indicate that other activities besides the high-intensity movements contribute significantly to the players' total match workload. Therefore, motion analysis alone may underestimate player load because many high-intensity actions are without a change in location at the pitch or they are classified as low-speed activity according to current standards. This new knowledge may help coaches to better understand the different ways players achieve match load and could be used in developing individualized programs that better meet the "positional physical demands" in elite soccer.
NASA Astrophysics Data System (ADS)
Nor, M. K. Mohd; Noordin, A.; Ruzali, M. F. S.; Hussen, M. H.; Mustapa@Othman, N.
2017-04-01
Simple Structural Surfaces (SSS) method is offered as a means of organizing the process for rationalizing the basic vehicle body structure load paths. The application of this simplified approach is highly beneficial in the development of modern passenger car structure design. In Malaysia, the SSS topic has been widely adopted and seems compulsory in various automotive programs related to automotive vehicle structures in many higher education institutions. However, there is no real physical model of SSS available to gain considerable insight and understanding into the function of each major subassembly in the whole vehicle structures. Based on this motivation, a real physical SSS of sedan model and the corresponding model vehicle tests of bending is proposed in this work. The proposed approach is relatively easy to understand as compared to Finite Element Method (FEM). The results prove that the proposed vehicle model test is useful to physically demonstrate the importance of providing continuous load path using the necessary structural components within the vehicle structures. It is clearly observed that the global bending stiffness reduce significantly when more panels are removed from the complete SSS model. The analysis shows the front parcel shelf is an important subassembly to sustain bending load.
Interactions Between Modality of Working Memory Load and Perceptual Load in Distractor Processing.
Koshino, Hideya; Olid, Pilar
2015-01-01
The present study investigated interactions between working memory load and perceptual load. The load theory (Lavie, Hirst, de Fockert, & Viding, 2004 ) claims that perceptual load decreases distractor interference, whereas working memory load increases interference. However, recent studies showed that effects of working memory might depend on the relationship between modalities of working memory and task stimuli. Here, we examined whether the relationship between working memory load and perceptual load would remain the same across modalities. The results of Experiment 1 showed that verbal working memory load did not affect a compatibility effect for low perceptual load, whereas it increased the compatibility effect for high perceptual load. In Experiment 2, the compatibility effect remained the same regardless of visual working memory load. These results suggest that the effects of working memory load and perceptual load depend on the relationship between the modalities of working memory and stimuli.
[Study on relationship between fatigue and work ability in chemistry workers].
Wu, Si-Ying; Wang, Mian-Zhen; Wang, Zhi-Ming; Lan, Ya-Jia
2005-01-01
Explore the relationship between fatigue and work ability in 976 chemistry workers. A test of fatigue and work ability was carried out with fatigue scale and work ability index (WAI) for 976 workers, other influence factors of the work ability (such as work environment, labor load, job factors) were investigated with questionnaire. (1) The frequency of fatigue of the unmarried workers was significantly lower than that of the married workers and other marital status workers, while the score of WAI of the unmarried was significantly higher than that of those( P < 0.05); (2) the frequency of fatigue of the mental workers was significantly lower than that of the mixed physical and mental workers, while the score of WAI of the mental workers was significantly higher than that of physical workers and mixed physical and mental workers ( P < 0.05); (3) compared with the workers free of fatigue, the other workers had lower WAI scores; (4) the fatigue score correlated negatively to the WAI score (r = -0.499, P < 0.01); (5) Cumulative odds model analysis showed that after controlling the other risk factors, fatigue was an important risk factor of work ability (OR = 4.005). Fatigue has affected work ability in chemistry workers, the frequency of fatigue is higher, the score of WAI is lower.
Kannan, Vinayagam; Balabathula, Pavan; Divi, Murali K; Thoma, Laura A; Wood, George C
2015-01-01
The effect of formulation and process parameters on drug loading and physical stability of paclitaxel-loaded long-circulating liposomes was evaluated. The liposomes were prepared by hydration-extrusion method. The formulation parameters such as total lipid content, cholesterol content, saturated-unsaturated lipid ratio, drug-lipid ratio and process parameters such as extrusion pressure and number of extrusion cycles were studied and their impact on drug loading and physical stability was evaluated. A proportionate increase in drug loading was observed with increase in the total phospholipid content. Cholesterol content and saturated lipid content in the bilayer showed a negative influence on drug loading. The short-term stability evaluation of liposomes prepared with different drug-lipid ratios demonstrated that 1:60 as the optimum drug-lipid ratio to achieve a loading of 1-1.3 mg/mL without the risk of physical instability. The vesicle size decreased with an increase in the extrusion pressure and number of extrusion cycles, but no significant trends were observed for drug loading with changes in process pressure or number of cycles. The optimization of formulation and process parameters led to a physically stable formulation of paclitaxel-loaded long-circulating liposomes that maintain size, charge and integrity during storage.
Measurement of fatigue in industries.
Saito, K
1999-04-01
Fatigue of workers is a complex phenomenon resulting from various factors in technically innovated modern industries, and it appears as a feeling of exhaustion, lowering of physiological functions, breakdown of autonomic nervous balance, and decrease in work efficiency. On the other hand industrial fatigue is caused by excessive workload, remarkable alteration in working posture and diurnal and nocturnal rhythms in daily life. Working modes in modern industries have changed from work with the whole body into that with the hands, arms, legs and/or eyes which are parts of the body, and from physical work to mental work. Visual display terminal (VDT) work is one of the most characteristic jobs in the various kinds of workplaces. A large number of fatigue tests have already been adopted, but it is still hard to draw a generalized conclusion as to the method of selecting the most appropriate test battery for a given work load. As apparatus for fatigue measurement of VDT work we have developed VRT (Visual Reaction Test) and the Portable Fatigue Meter. Furthermore, we have presented immune parameters of peripheral blood and splenic T cells for physical fatigue.
Liebers, Falk; Brandstädt, Felix; Schust, Marianne; Serafin, Patrick; Schäfer, Andreas; Gebhardt, Hansjürgen; Hartmann, Bernd; Steinberg, Ulf
2017-01-01
Introduction The impact of work-related musculoskeletal disorders is considerable. The assessment of work tasks with physical workloads is crucial to estimate the work-related health risks of exposed employees. Three key indicator methods are available for risk assessment regarding manual lifting, holding and carrying of loads; manual pulling and pushing of loads; and manual handling operations. Three further KIMs for risk assessment regarding whole-body forces, awkward body postures and body movement have been developed de novo. In addition, the development of a newly drafted combined method for mixed exposures is planned. All methods will be validated regarding face validity, reliability, convergent validity, criterion validity and further aspects of utility under practical conditions. Methods and analysis As part of the joint project MEGAPHYS (multilevel risk assessment of physical workloads), a mixed-methods study is being designed for the validation of KIMs and conducted in companies of different sizes and branches in Germany. Workplaces are documented and analysed by observations, applying KIMs, interviews and assessment of environmental conditions. Furthermore, a survey among the employees at the respective workplaces takes place with standardised questionnaires, interviews and physical examinations. It is intended to include 1200 employees at 120 different workplaces. For analysis of the quality criteria, recommendations of the COSMIN checklist (COnsensus-based Standards for the selection of health Measurement INstruments) will be taken into account. Ethics and dissemination The study was planned and conducted in accordance with the German Medical Professional Code and the Declaration of Helsinki as well as the German Federal Data Protection Act. The design of the study was approved by ethics committees. We intend to publish the validated KIMs in 2018. Results will be published in peer-reviewed journals, presented at international meetings and disseminated to actual users for practical application. PMID:28827239
Klussmann, Andre; Liebers, Falk; Brandstädt, Felix; Schust, Marianne; Serafin, Patrick; Schäfer, Andreas; Gebhardt, Hansjürgen; Hartmann, Bernd; Steinberg, Ulf
2017-08-21
The impact of work-related musculoskeletal disorders is considerable. The assessment of work tasks with physical workloads is crucial to estimate the work-related health risks of exposed employees. Three key indicator methods are available for risk assessment regarding manual lifting, holding and carrying of loads; manual pulling and pushing of loads; and manual handling operations. Three further KIMs for risk assessment regarding whole-body forces, awkward body postures and body movement have been developed de novo. In addition, the development of a newly drafted combined method for mixed exposures is planned. All methods will be validated regarding face validity, reliability, convergent validity, criterion validity and further aspects of utility under practical conditions. As part of the joint project MEGAPHYS (multilevel risk assessment of physical workloads), a mixed-methods study is being designed for the validation of KIMs and conducted in companies of different sizes and branches in Germany. Workplaces are documented and analysed by observations, applying KIMs, interviews and assessment of environmental conditions. Furthermore, a survey among the employees at the respective workplaces takes place with standardised questionnaires, interviews and physical examinations. It is intended to include 1200 employees at 120 different workplaces. For analysis of the quality criteria, recommendations of the COSMIN checklist (COnsensus-based Standards for the selection of health Measurement INstruments) will be taken into account. The study was planned and conducted in accordance with the German Medical Professional Code and the Declaration of Helsinki as well as the German Federal Data Protection Act. The design of the study was approved by ethics committees. We intend to publish the validated KIMs in 2018. Results will be published in peer-reviewed journals, presented at international meetings and disseminated to actual users for practical application. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
Development of serratiopeptidase and metronidazole based alginate microspheres for wound healing.
Rath, G; Johal, E S; Goyal, Amit K
2011-02-01
The objective of this study was to establish an effective therapy system for wound management. The present work describes preparation of metronidazole/serratiopeptidase loaded alginate microspheres by emulsification method. In vitro characterizations like particle size analysis, % yield, % encapsulation, and in vitro release were carried out. Wound healing assessment was determined by physical, histological, and biochemical methods. Wound healing performance of experimental formulations was compared with marketed product in rabbits. Result obtained for alginate microspheres showed good loading efficiency with spherical in shape. Experimentation suggests wound healing is improved by using serratiopeptidase and metronidazole in full thickness wounds in rabbits.
Loading rate effect on nanohardness of human enamel
NASA Astrophysics Data System (ADS)
Biswas, Nilormi; Dey, Arjun; Mukhopadhyay, Anoop K.
2012-07-01
In the present work, nanoindentation technique has been utilised to study the physics of deformation at the scale of micro/nano-structure of tooth enamel which is basically the hardest natural biomaterial in the human body comprising of a hybrid combination of hydroxypatite ceramic nano-crystal and organic-protein matrix. We have observed about 8 % increase in the nanohardness of human enamel with the increase in loading rate from 1 × 103 μN s-1 to 3 × 105 μN s-1. The results have been explained in terms of the maximum shear stress generated underneath the nanoindenter.
Chan, Cliffton; Ackermann, Bronwen
2014-01-01
Playing a musical instrument at an elite level is a highly complex motor skill. The regular daily training loads resulting from practice, rehearsals and performances place great demands on the neuromusculoskeletal systems of the body. As a consequence, performance-related musculoskeletal disorders (PRMDs) are globally recognized as common phenomena amongst professional orchestral musicians. These disorders create a significant financial burden to individuals and orchestras as well as lead to serious consequences to the musicians’ performance and ultimately their career. Physical therapists are experts in treating musculoskeletal injuries and are ideally placed to apply their skills to manage PRMDs in this hyper-functioning population, but there is little available evidence to guide specific injury management approaches. An Australia-wide survey of professional orchestral musicians revealed that the musicians attributed excessively high or sudden increase in playing-load as major contributors to their PRMDs. Therefore, facilitating musicians to better manage these loads should be a cornerstone of physical therapy management. The Sound Practice orchestral musicians work health and safety project used formative and process evaluation approaches to develop evidence-informed and clinically applicable physical therapy interventions, ultimately resulting in favorable outcomes. After these methodologies were employed, the intervention studies were conducted with a national cohort of professional musicians including: health education, onsite injury management, cross-training exercise regimes, performance postural analysis, and music performance biomechanics feedback. The outcomes of all these interventions will be discussed alongside a focussed review on the existing literature of these management strategies. Finally, a framework for best-practice physical therapy management of PRMDs in musicians will be provided. PMID:25071671
El-Hadidy, Gladious Naguib; Ibrahim, Howida Kamal; Mohamed, Magdi Ibrahim; El-Milligi, Mohamed Farid
2012-01-01
This work was undertaken to investigate microemulsion (ME) as a topical delivery system for the poorly water-soluble voriconazole. Different ME components were selected for the preparation of plain ME systems with suitable rheological properties for topical use. Two permeation enhancers were incorporated, namely sodium deoxycholate or oleic acid. Drug-loaded MEs were evaluated for their physical appearance, pH, rheological properties and in vitro permeation studies using guinea pig skin. MEs based on polyoxyethylene(10)oleyl ether (Brij 97) as the surfactant showed pseudoplastic flow with thixotropic behavior and were loaded with voriconazole. Jojoba oil-based MEs successfully prolonged voriconazole release up to 4 h. No significant changes in physical or rheological properties were recorded on storage for 12 months at ambient conditions. The presence of permeation enhancers favored transdermal rather than dermal delivery. Sodium deoxycholate was more effective than oleic acid for enhancing the voriconazole permeation. Voriconazole-loaded MEs, with and without enhancers, showed significantly better antifungal activity against Candida albicans than voriconazole supersaturated solution. In conclusion, the studied ME formulae could be promising vehicles for topical delivery of voriconazole.
The impact of physical and mental tasks on pilot mental workoad
NASA Technical Reports Server (NTRS)
Berg, S. L.; Sheridan, T. B.
1986-01-01
Seven instrument-rated pilots with a wide range of backgrounds and experience levels flew four different scenarios on a fixed-base simulator. The Baseline scenario was the simplest of the four and had few mental and physical tasks. An activity scenario had many physical but few mental tasks. The Planning scenario had few physical and many mental taks. A Combined scenario had high mental and physical task loads. The magnitude of each pilot's altitude and airspeed deviations was measured, subjective workload ratings were recorded, and the degree of pilot compliance with assigned memory/planning tasks was noted. Mental and physical performance was a strong function of the manual activity level, but not influenced by the mental task load. High manual task loads resulted in a large percentage of mental errors even under low mental task loads. Although all the pilots gave similar subjective ratings when the manual task load was high, subjective ratings showed greater individual differences with high mental task loads. Altitude or airspeed deviations and subjective ratings were most correlated when the total task load was very high. Although airspeed deviations, altitude deviations, and subjective workload ratings were similar for both low experience and high experience pilots, at very high total task loads, mental performance was much lower for the low experience pilots.
[Working conditions of community nurses].
Kułagowska, Ewa; Kosińska, Maria
2010-01-01
To ensure the most efficient workplace health promotion it is essential to identify and monitor health conditions of employees and all components of the work process, as well as to recognize their cause-effect relationships. Community nurses form an occupational group with a specific type of workplace that is usually located in the patient's place of residence and thus not inspected in terms of safety and hygiene. The aim of the study was to identify working conditions of community nurses with special reference to occupational hazards. An anonymous questionnaire was used as a major tool of this survey. It contained 33 questions, concerning the work process, working conditions, work loads and arduousness, hazards and work-related complaints. The questionnaire was completed by 86 community nurses working in the Upper Silesia region. Community nurses generally assessed their work as hard. A more thorough analysis revealed that nursing and curative care, nursing and hygienic care and rehabilitation were regarded by community nurses as hard, whereas social diagnostics and curative diagnostics were assessed as much easier tasks. Excessive physical load, forced position at work, aggressive patients, patients' aggressive family members, dangerous domestic animals, low quality of technical devices in patients' homes were reported as the greatest hazards. The obtained results reveal that working conditions of community nurses do not ensure their safety at work.
Physical load handling and listening comprehension effects on balance control.
Qu, Xingda
2010-12-01
The purpose of this study was to determine the physical load handling and listening comprehension effects on balance control. A total of 16 young and 16 elderly participants were recruited in this study. The physical load handling task required holding a 5-kg load in each hand with arms at sides. The listening comprehension task involved attentive listening to a short conversation. Three short questions were asked regarding the conversation right after the testing trial to test the participants' attentiveness during the experiment. Balance control was assessed by centre of pressure-based measures, which were calculated from the force platform data when the participants were quietly standing upright on a force platform. Results from this study showed that both physical load handling and listening comprehension adversely affected balance control. Physical load handling had a more deleterious effect on balance control under the listening comprehension condition vs. no-listening comprehension condition. Based on the findings from this study, interventions for the improvement of balance could be focused on avoiding exposures to physically demanding tasks and cognitively demanding tasks simultaneously. STATEMENT OF RELEVANCE: Findings from this study can aid in better understanding how humans maintain balance, especially when physical and cognitive loads are applied. Such information is useful for developing interventions to prevent fall incidents and injuries in occupational settings and daily activities.
Sensing power transfer between the human body and the environment.
Veltink, Peter H; Kortier, Henk; Schepers, H Martin
2009-06-01
The power transferred between the human body and the environment at any time and the work performed are important quantities to be estimated when evaluating and optimizing the physical interaction between the human body and the environment in sports, physical labor, and rehabilitation. It is the objective of the current paper to present a concept for estimating power transfer between the human body and the environment during free motions and using sensors at the interface, not requiring measurement systems in the environment, and to experimentally demonstrate this principle. Mass and spring loads were moved by hand over a fixed height difference via varying free movement trajectories. Kinematic and kinetic quantities were measured in the handle between the hand and the load. 3-D force and moments were measured using a 6 DOF force/moment sensor module, 3-D movement was measured using 3-D accelerometers and angular velocity sensors. The orientation was estimated from the angular velocity, using the initial orientation as a begin condition. The accelerometer signals were expressed in global coordinates using this orientation information. Velocity was estimated by integrating acceleration in global coordinates, obtained by adding gravitational acceleration to the accelerometer signals. Zero start and end velocities were used as begin and end conditions. Power was calculated as the sum of the inner products of velocity and force and of angular velocity and moment, and work was estimated by integrating power over time. The estimated performed work was compared to the potential energy difference corresponding to the change in height of the loads and appeared to be accurate within 4% for varying movements with net displacements and varying loads (mass and spring). The principle of estimating power transfer demonstrated in this paper can be used in future interfaces between the human body and the environment instrumented with body-mounted miniature 3-D force and acceleration sensors.
Gyemi, Danielle L; van Wyk, Paula M; Statham, Melissa; Casey, Jeff; Andrews, David M
2016-01-01
In agricultural field work many tasks have been cited as high priority risk factors for the development of work-related musculoskeletal disorders (WRMDs). Although video-based biomechanical approaches have been effective in documenting the physical demands and risks associated with various occupational and non-occupational tasks, to date, this method has yet to be used to document jobs such as crop harvesting in a greenhouse environment. To document and assess the postural characteristics and 3D peak and cumulative low back and shoulder loads associated with greenhouse pepper harvesting using a video-based posture sampling approach. Nine male (28.2 (4.1) years) pepper harvesters from a greenhouse in Southwestern Ontario, Canada were videotaped during a normal shift. 3DMatch was used to document working trunk and shoulder postures, from which 3D peak and cumulative forces and moments were quantified. On average, workers spent the majority of their time in neutral trunk postures (lateral bend: 99.1%; axial twist: 59.9%; flexion: 89.8%). Consistent results were found for the left and right shoulder, with the arms held in a neutral flexion posture 50% of the time or more. Four participants experienced peak L4/L5 compression forces (between 4116.3 N and 5937.0 N) which exceeded the NIOSH Action Limit (3400 N) during the cart pushing/pulling task, but remained below the threshold during picking. Mean cumulative L4/L5 extension and shoulder flexion moments ranged in magnitude from 18.5 Nm to 28.2 Nm, and between 19.4 Nm and 23.2 Nm, respectively, across all tasks. The postural characteristics and biomechanical loads associated with greenhouse pepper harvesting were quantified with a video-based biomechanical approach. Further investigations of the physical risk factors for low back and shoulder musculoskeletal disorders is warranted in pepper harvesting, given the postures and loads documented in this study.
ERIC Educational Resources Information Center
Adeniyi, S. O.; Fakolade, Olufemi Aremum; Tella, Adeyinka
2010-01-01
Background: Efficient and effective performance on any job depend largely on good psychological well being of the workers as well as other factors such as conducive environment, good interpersonal relationship, adequate communication among staff and between staff and management, work load, remuneration and other physical and psychological boosting…
A Force Transducer from a Junk Electronic Balance
ERIC Educational Resources Information Center
Aguilar, Horacio Munguia; Aguilar, Francisco Armenta
2009-01-01
It is shown how the load cell from a junk electronic balance can be used as a force transducer for physics experiments. Recovering this device is not only an inexpensive way of getting a valuable laboratory tool but also very useful didactic work on electronic instrumentation. Some experiments on mechanics with this transducer are possible after a…
The Main Reciprocal for Teaching Load: Faculty Use of Research Time.
ERIC Educational Resources Information Center
Colbeck, Carol L.
This study examined the allocation of time college faculty give to various research tasks. Case studies were conducted of 12 faculty members in four departments selected for variation by university type (research and comprehensive) and discipline (Physics and English). The work of each faculty member was observed on five non-consecutive days for a…
Condition of cardiovascular systems of astronauts during flight of Soyuz orbital station
NASA Technical Reports Server (NTRS)
Degtyarev, V. A.; Popov, I. I.; Batenchuk-Tusko, T. V.; Kolmykova, N. D.; Lapshina, N. A.; Kirillova, Z. A.; Doroshev, V. G.; Kukushkin, Y. A.
1975-01-01
Extensive studies of blood circulation functions during manned space flight demonstrated a pronounced tendency toward an increase in minute volume of the blood and a decrease in pulse wave propagation rate. Individual blood circulation indices had large amplitude fluctuations. Physical work loads caused slow recovery of heart rate, arterial pressure and minute blood volume.
Evaluation of working conditions of workers engaged in tending horses.
Nowakowicz-Dębek, Bożena; Pawlak, Halina; Wlazło, Łukasz; Kuna-Broniowska, Izabela; Bis-Wencel, Hanna; Buczaj, Agnieszka; Maksym, Piotr
2014-01-01
A growing interest in the horse business has resulted in the increased engagement of many people in this area, and the health problems occurring among workers create the need to search for prophylactic measures. The objective of the study was evaluation of the level of exposure to air pollution in a stable, and estimation of the degree of work load among workers engaged in tending horses. The study was conducted twice, during the winter season, in a stable maintaining race horses, and in a social room. In order to evaluate workers' exposure, air samples were collected by the aspiration method. After the incubation of material, the total number of bacteria and fungi in the air was determined, as well as the number of aerobic mesophilic and thermophilic bacteria, expressed as the number of colony forming units per cubic meter of air (CFU/m3). The measurement of total dust concentration in the air was also performed, simultaneously with the measurement of microclimatic parameters. The study of work load also covered the measurement of energy expenditure, evaluation of static physical load, and monotony of movements performed. The stable may be considered as a workplace with considerable risk of the occurrence of unfavourable health effects.
Ratings of perceived exertion by women with internal or external locus of control.
Hassmén, P; Koivula, N
1996-10-01
Ratings of perceived exertion are frequently used to estimate the strain and effort experienced subjectively by individuals during various forms of physical activity. A number of factors, both physiological and psychological in origin, have been suggested to work as modifiers of the exertion perceived by the individual. It has been reported in nonsport-related research that individuals with an internal locus of control seem to pay more attention to relevant information and use the available information more adequately than individuals with an external locus of control. The reputed inferior information-processing abilities of externals compared with internals could possibly also influence the ratings of perceived exertion, with externals being less accurate in their ratings. Whether locus of control might be such a factor was investigated. Fifty women worked on an ergometer cycle at four different work loads. The results showed statistically significant differences in subjective ratings of perceived exertion between externals and internals, especially at heavier work loads. Such differences might be because of unequal information-processing abilities, as the observed discrepancies occurred at higher work intensities, when more cues are available for processing.
Work injuries among drivers in the goods-transport branch in Denmark.
Shibuya, Hitomi; Cleal, Bryan; Mikkelsen, Kim Lyngby
2008-05-01
Goods-transport drivers in Denmark had an elevated rate of hospital contact due to injury compared with the skilled/semiskilled workforce in general in recent years. There is a need to elucidate the causes of their work injuries. We analyzed the Danish National Work Injury Register for the 10-year period 1993-2002. The vast majority (92.6%) of the work injuries among goods-transport were sustained under non-traffic activities, that is, collecting, loading, unloading, and delivering goods. They fell from height (22.3%), suffered from overexertion (14.2%), got caught between/under objects (12.6%), collided with objects (12.0%), slipped/tripped (10.6%), or got struck by falling objects (9.0%). There is a clear need for efforts to prevent work injuries under non-traffic activities among goods-transport drivers in Denmark. For this end, it is necessary to involve not only the drivers' employers for reinforcement of safety procedures, but also the employers' customers for improvement of the physical environment, in which drivers collect, load, unload, and deliver goods. (c) 2008 Wiley-Liss, Inc.
Managing player load in professional rugby union: a review of current knowledge and practices.
Quarrie, Kenneth L; Raftery, Martin; Blackie, Josh; Cook, Christian J; Fuller, Colin W; Gabbett, Tim J; Gray, Andrew J; Gill, Nicholas; Hennessy, Liam; Kemp, Simon; Lambert, Mike; Nichol, Rob; Mellalieu, Stephen D; Piscione, Julien; Stadelmann, Jörg; Tucker, Ross
2017-03-01
The loads to which professional rugby players are subjected has been identified as a concern by coaches, players and administrators. In November 2014, World Rugby commissioned an expert group to identify the physical demands and non-physical load issues associated with participation in professional rugby. To describe the current state of knowledge about the loads encountered by professional rugby players and the implications for their physical and mental health. The group defined 'load' as it relates to professional rugby players as the total stressors and demands applied to the players. In the 2013-2014 seasons, 40% of professional players appeared in 20 matches or more, and 5% of players appeared in 30 matches or more. Matches account for ∼5-11% of exposure to rugby-related activities (matches, team and individual training sessions) during professional competitions. The match injury rate is about 27 times higher than that in training. The working group surmised that players entering a new level of play, players with unresolved previous injuries, players who are relatively older and players who are subjected to rapid increases in load are probably at increased risk of injury. A mix of 'objective' and 'subjective' measures in conjunction with effective communication among team staff and between staff and players was held to be the best approach to monitoring and managing player loads. While comprehensive monitoring holds promise for individually addressing player loads, it brings with it ethical and legal responsibilities that rugby organisations need to address to ensure that players' personal information is adequately protected. Administrators, broadcasters, team owners, team staff and the players themselves have important roles in balancing the desire to have the 'best players' on the field with the ongoing health of players. In contrast, the coaching, fitness and medical staff exert significant control over the activities, duration and intensity of training sessions. If load is a major risk factor for injury, then managing training loads should be an important element in enabling players to perform in a fit state as often as possible. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.
[Framework of work stress for the evaluation and management of risk].
Costa, G
2009-01-01
Occupational stress is the negative consequence of a distorted relation between the worker and the work environment (mental/physical load, work organisation, social relationships), where both components, that is work demands and human resources, are strictly interacting in causing more or less severe mal-adjustment and health impairment. This is mediated by several intervening factors, related not only to high cognitive and emotional stress, but also to scarce coping strategies, that are strongly influenced by personal characteristics, lack of control on working conditions, and social support. Hence high costs for the individual, the company and the whole society, not only in terms of workers' health and well-being, but also as regards work ability and performance efficiency, as well as social consequences and compensative interventions. The Occupational Health Physician has to deal with these multidimensional and multifaceted aspects of work stress by different and concurrent approaches, at both group and individual levels, with epidemiological and clinical perspectives, enacting preventive and therapeutic strategies. Both "external" work load and individual "responses" have to be properly considered and addressed not only for the evaluation of at fitness to work, but also to plan corrective actions. Hence, the OHP has to act in closer collaboration with work psychologists, sociologists, human resources managers and work organisation experts.
Doan, Jon B; Copeland, Jennifer L; Brown, Lesley A; Newman, Jeff T; Hudson, D Shane
2014-01-01
Bridge employment (scheduled paid work after retirement age) may promote successful aging and continued health, as work can be an important component of daily physical activity. Appropriate work demands for older adults are neither well-established nor well-applied, however, and excessive loading or increased perceptions of discomfort may negate the health benefits of work activity. This study examined work status and musculoskeletal discomfort (MSD) amongst older Albertans. 1044 Albertans aged 55 years and older participating in an organized 'Games' received a research package. Enclosed in the package were an introductory letter, a return envelope, and modified versions of validated questionnaires examining leisure and work activities, activity frequency, and perceptions of musculoskeletal health. 228 respondents were classified into one of three employment trajectory groups: fully retired, fully employed, or bridge employed. Groups differed in age, and both employed groups more frequently reported MSDs in all body areas. Bridge employed reported increased 'occasional' frequency of musculoskeletal injury risk factors, while both groups reported similar overall ratings of work-related exertion. The increased MSDs reported by bridge employed adults may be the result of irregularity of work activity and soft tissue loading. Detailed examination of work demands and musculoskeletal injuries amongst bridge employed adults could help define safer levels for less regular work activity.
2003-10-01
of NSAIDs and the management of NSAID -related gastropathy in medical practice.Ann Intern Med. 1997 Sep 15;127(6):429-38. USACHPPM Report No. 21-KK...anti-inflammatory drug ( NSAID ) and injury, prevention, exercise, pre-exercise, loading, anti-inflammatory. b. Total number of hits resulting...damage beyond that originally sustained by the muscle. It is hypothesized that administration of a NSAID prior to an exercise would control that
NASA Astrophysics Data System (ADS)
Yakovlev, A. A.; Sorokin, V. S.; Mishustina, S. N.; Proidakova, N. V.; Postupaeva, S. G.
2017-01-01
The article describes a new method of search design of refrigerating systems, the basis of which is represented by a graph model of the physical operating principle based on thermodynamical description of physical processes. The mathematical model of the physical operating principle has been substantiated, and the basic abstract theorems relatively semantic load applied to nodes and edges of the graph have been represented. The necessity and the physical operating principle, sufficient for the given model and intended for the considered device class, were demonstrated by the example of a vapour-compression refrigerating plant. The example of obtaining a multitude of engineering solutions of a vapour-compression refrigerating plant has been considered.
Working spectacles for sorting mail.
Hemphälä, Hillevi; Dahlqvist, Camilla; Nordander, Catarina; Gao, Chuansi; Kuklane, Kalev; Nylén, Per; Hansson, Gert-Åke
2014-01-01
Sorting mail into racks for postmen is visually demanding work. This can result in backward inclination of their heads, especially more pronounced for those who use progressive addition lenses. To evaluate the effects of customized working spectacles on the physical workload of postmen. Twelve male postmen sorted mail on two occasions: once using their private progressive spectacles and once using customized sorting spectacles with inverted progressive lenses. Postures and movements of the head, upper back, neck, and upper arms were measured by inclinometry. The muscular load of the trapezius was measured by surface electromyography. With the customized sorting spectacles, both the backward inclination of the head and backward flexion of the neck were reduced (3°), as well as the muscular load of the right upper trapezius, compared to sorting with private spectacles. However, with the sorting spectacles, there was a tendency for increased neck forward flexion, and increased sorting time. The reduction in work load may reduce the risk for developing work-related musculoskeletal disorders due to the positive reduction of the backward inclination of the head. But the tendency for increased neck forward flexion may reduce the positive effects. However, the magnitude of the possible reduction is difficult to predict, especially since quantitative data on exposure-response relationships are unknown. Alternative working spectacles with inverted near progressive lenses ought to be evaluated. They should still result in a positive reduced backward inclination of the head and may not cause any increased forward flexion.
Gooyers, Chad E; Frost, David M; McGill, Stuart M; Callaghan, Jack P
2013-04-01
In this case report an incumbent firefighter partially ruptured his right Achilles tendon during a study of the physical demands of firefighting. Kinematics and kinetics of the lower limbs and trunk were collected while the firefighter performed two simulated fire ground tasks. From this unexpected event, two insights were obtained that should be considered in all future injury prevention and reporting efforts. (i) Consider the full anatomical linkage--the right ankle and knee kinematics leading up to the onset of injury trial were comparable to all preceding repetitions. However, there was a notable difference in the left knee starting position before the initiation of movement of the 37th hose-advance trial. (ii) Consider the cumulative load--the task in question comprised forward and backward phases. A marked difference was observed in the frontal-plane ankle moment during the return phase of the trial preceding the injury. Additionally, the magnitude of the left side vertical ground reaction force was comparable across all trials, suggesting that loads experienced by the right limb were also similar. This would indicate that the tolerance of the Achilles tendon and not the magnitude of the loading was altered. The unfortunate injury captured in this work provides insight into the complexity of characterizing the pathways of injury. It is recommended that future injury prevention and reporting efforts consider individuals' physical demands (at work and in life) and document the nature of loading (i.e., frequency, duration, magnitude, type) when considering the mechanism for injury. Crown Copyright © 2013. Published by Elsevier Ltd. All rights reserved.
15. BUILDING NO. 445, PHYSICS LAB (FORMERLY GUN BAG LOADING), ...
15. BUILDING NO. 445, PHYSICS LAB (FORMERLY GUN BAG LOADING), INTERIOR, FOURTH LEVEL. POWDER HOPPER AT TOP OF ELEVATOR SHAFT. POWDER DISTRIBUTED FROM HERE TO LOADING ROOMS BY TUBES. - Picatinny Arsenal, 400 Area, Gun Bag Loading District, State Route 15 near I-80, Dover, Morris County, NJ
Constitutive Modeling of the Dynamic-Tensile-Extrusion Test of PTFE
NASA Astrophysics Data System (ADS)
Resnyansky, Anatoly; Brown, Eric; Trujillo, Carl; Gray, George
2015-06-01
Use of polymers in the defence, aerospace and industrial application at extreme conditions makes prediction of behaviour of these materials very important. Crucial to this is knowledge of the physical damage response in association with the phase transformations during the loading and the ability to predict this via multi-phase simulation taking the thermodynamical non-equilibrium and strain rate sensitivity into account. The current work analyses Dynamic-Tensile-Extrusion (DTE) experiments on polytetrafluoroethylene (PTFE). In particular, the phase transition during the loading with subsequent tension are analysed using a two-phase rate sensitive material model implemented in the CTH hydrocode and the calculations are compared with experimental high-speed photography. The damage patterns and their link with the change of loading modes are analysed numerically and are correlated to the test observations.
Computer use, symptoms, and quality of life.
Hayes, John R; Sheedy, James E; Stelmack, Joan A; Heaney, Catherine A
2007-08-01
To model the effects of computer use on reported visual and physical symptoms and to measure the effects upon quality of life measures. A survey of 1000 university employees (70.5% adjusted response rate) assessed visual and physical symptoms, job, physical and mental demands, ability to control/influence work, amount of work at a computer, computer work environment, relations with others at work, life and job satisfaction, and quality of life. Data were analyzed to determine whether self-reported eye symptoms are associated with perceived quality of life. The study also explored the factors that are associated with eye symptoms. Structural equation modeling and multiple regression analyses were used to assess the hypotheses. Seventy percent of the employees used some form of vision correction during computer use, 2.9% used glasses specifically prescribed for computer use, and 8% had had refractive surgery. Employees spent an average of 6 h per day at the computer. In a multiple regression framework, the latent variable eye symptoms was significantly associated with a composite quality of life variable (p = 0.02) after adjusting for job quality, job satisfaction, supervisor relations, co-worker relations, mental and physical load of the job, and job demand. Age and gender were not significantly associated with symptoms. After adjusting for age, gender, ergonomics, hours at the computer, and exercise, eye symptoms were significantly associated with physical symptoms (p < 0.001) accounting for 48% of the variance. Environmental variability at work was associated with eye symptoms and eye symptoms demonstrated a significant impact on quality of life and physical symptoms.
[Physical workload and maximum acceptable work time among supermarket workers in Cali, Colombia].
Ariza, Luz Elena; Idrovo, Alvaro Javier
2005-01-01
In order to guarantee safety and health conditions in labor the maximum physical workload that can be supported by a worker during a labor day, without causing fatigue, must be determined. The objective of this study was to determine the relationship between the physical load, expressed as relative heart rate (RHR), and the maximum acceptable work time (MAWT) in a Colombian working population (n = 30) from a tropical environment. An observational study was carried out during a typical labor day in the warehouses of a supermarket. Physiological, demographic, health and labor conditions data were collected. The resting heart rate level and the average heart rate during work were measured, and the RHR was estimated according to with the model described by Wu & Wang. Significant correlations between MAWT and RHR and other physiological variables were observed. 43% of workers didn't fulfill the MAWT. The only single variable that was associated with fulfillment was a body mass index under 18.5 Kg/m2; the other associated variables were some specific conditions of the occupational environment. Results showed a negative correlation between physiological variables and MAWT. The RHR showed its potential usefulness in the enterprise's occupational health practice. It is important for companies to diminish extended schedules and implement physical conditioning programs.
Using Multiple Ways to Investigate Cognitive Load Theory in the Context of Physics Instruction
NASA Astrophysics Data System (ADS)
Zu, Tianlong
Cognitive load theory (CLT) (Sweller 1988, 1998, 2010) provides us a guiding framework for designing instructional materials. CLT differentiates three subtypes of cognitive load: intrinsic, extraneous, and germane cognitive load. The three cognitive loads are theorized based on the number of simultaneously processed elements in working memory. Intrinsic cognitive load depends upon the number of interacting elements in the instructional material that are related to the learning objective. Extraneous cognitive load is the mental resources allocated to processing unnecessary information which does not contribute to learning as caused by non- optimal instructional procedure. It is determined by the number of interacting elements which are not related to learning goal. Both intrinsic and extraneous load vary according to prior knowledge of learners. Germane cognitive load is indirectly related to interacting elements. It represents the cognitive resources deployed for processing intrinsic load, chunking information and constructing and automating schema. Germane cognitive load is related to level of motivation of the learner. Given this triarchic model of cognitive load and their different roles in learning activities, different learning outcomes can be expected depending upon the characteristics of the educational materials, learner characteristics, and instructional setting. In three experiments, we investigated cognitive load theory following different approaches. Given the triarchic nature of cognitive load construct, it is critical to find non- intrusive ways to measure cognitive load. In study one, we replicated and extended a previous landmark study to investigate the use of eye movements related metrics to measure the three kinds of cognitive load independently. We also collected working memory capacity of students using a cognitive operation-span task. Two of the three types of cognitive load (intrinsic and extraneous) were directly manipulated, and the third type of cognitive load (germane) was indirectly ascertained. We found that different eye-movement based parameters were most sensitive to different types of cognitive load. These results indicate that it is possible to monitor the three kinds of cognitive load separately using eye movement parameters. We also compared the up-to-date cognitive load theory model with an alternative model using a multi-level model analysis and we found that Sweller's (2010) up-to-date model is supported by our data. In educational settings, active learning based methodologies such as peer instruction have been shown to be effective in facilitating students' conceptual understanding. In study two, we discussed the effect of peer interaction on conceptual test performance of students from a cognitive load perspective. Based on the literature, a self-reported cognitive load survey was developed to measure each type of cognitive load. We found that a certain level of prior knowledge is necessary for peer interaction to work and that peer interaction is effective mainly through significantly decreasing the intrinsic load experienced by students, even though it may increase the extraneous load. In study three, we compared the effect of guided instruction in the form of worked examples using narrated-animated video solutions and semi-guided instruction using visual cues on students' performance, shift of visual attention during transfer, and extraneous cognitive load during learning. We found that multimedia video solutions can be more effective in promoting transfer performance of learners than visual cues. We also found evidence that guided instruction in the form of multimedia video solutions can decrease extraneous cognitive load of students during learning, more so than semi-guided instruction using visual cues.
13. BUILDING NO. 445, PHYSICS LAB (FORMERLY GUN BAG LOADING), ...
13. BUILDING NO. 445, PHYSICS LAB (FORMERLY GUN BAG LOADING), VIEW NORTH AT SOUTH END OF BUILDING. - Picatinny Arsenal, 400 Area, Gun Bag Loading District, State Route 15 near I-80, Dover, Morris County, NJ
Work, work-life conflict and health in an industrial work environment.
Hämmig, O; Bauer, G F
2014-01-01
Work-life conflict has been poorly studied as a cause of ill-health in occupational medicine. To study associations between physical and psychosocial working conditions, including work-life conflict on the one hand and general, physical and mental health outcomes on the other. Cross-sectional data were used from an employee survey among the workforces of four medium-sized and large companies in Switzerland. Physical work factors included five demands and exposures such as heavy loads, repetitive work and poor posture. Psychosocial factors included 14 demands and limited resources such as time pressure, overtime, monotonous work, job insecurity, low job autonomy, low social support and work-life conflict. Health outcomes studied were self-rated health, sickness absence, musculoskeletal disorders, sleep disorders, stress and burnout. There was a response rate of 49%; 2014 employees participated. All adverse working conditions were positively associated with several poor health outcomes in both men and women. After mutual adjustment for all work factors and additional covariates, only a few, mainly psychosocial work factors remained significant as risk factors for health. Work-life conflict, a largely neglected work-related psychosocial factor in occupational medicine, turned out to be the only factor that was significantly and strongly associated with all studied health outcomes and was consistently found to be the strongest or second strongest of all the studied risk factors. Even in an industrial work environment, psychosocial work factors, and particularly work-life conflict, play a key role and need to be taken into consideration in research and workplace health promotion.
Design and develop speed/pressure regulator
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hasanul Basher, A.M.
1993-09-01
The Physics Division at Oak Ridge National Laboratory has several recirculating water cooling systems. One of them supplies deionized water at 150 psi, which is mainly used for cooling magnet windings at the Oak Ridge Isochronous Cyclotron (ORIC). The system has three 125-hp water pumps, each of which is capable of supplying water at the rate of 1000 gpm. One of the major requirements of this water supply system is that the supply pressure must be kept constant. An adjustable-frequency speed controller was recently installed to control the speed of one of the pump motors. A servo-system was provided withmore » the adjustable-frequency controller for regulating motor speed and, subsequently, the water pressure. After unsuccessful attempts to operate the servo, it was concluded that the regulator may not work for the existing system. Prior to installation of the variable-frequency controller, pressure regulation was accomplished with a pneumatically controlled load by-pass valve. To maintain constant pressure in the system, it is necessary to run always at full load, even if full load is not on the system. Hence, there is a waste of energy when full load is not connected to the system. So, designing and implementing one regulator that works at any load condition has become necessary. This report discusses the design of such a pressure regulator.« less
Seidler, Andreas; Bolm-Audorff, Ulrich; Abolmaali, Nasreddin; Elsner, Gine
2008-01-01
Objectives To examine the dose-response relationship between cumulative exposure to kneeling and squatting as well as to lifting and carrying of loads and symptomatic knee osteoarthritis (OA) in a population-based case-control study. Methods In five orthopedic clinics and five practices we recruited 295 male patients aged 25 to 70 with radiographically confirmed knee osteoarthritis associated with chronic complaints. A total of 327 male control subjects were recruited. Data were gathered in a structured personal interview. To calculate cumulative exposure, the self-reported duration of kneeling and squatting as well as the duration of lifting and carrying of loads were summed up over the entire working life. Results The results of our study support a dose-response relationship between kneeling/squatting and symptomatic knee osteoarthritis. For a cumulative exposure to kneeling and squatting > 10.800 hours, the risk of having radiographically confirmed knee osteoarthritis as measured by the odds ratio (adjusted for age, region, weight, jogging/athletics, and lifting or carrying of loads) is 2.4 (95% CI 1.1–5.0) compared to unexposed subjects. Lifting and carrying of loads is significantly associated with knee osteoarthritis independent of kneeling or similar activities. Conclusion As the knee osteoarthritis risk is strongly elevated in occupations that involve both kneeling/squatting and heavy lifting/carrying, preventive efforts should particularly focus on these "high-risk occupations". PMID:18625053
Mathematical modeling of a four-stroke resonant engine for micro and mesoscale applications
NASA Astrophysics Data System (ADS)
Preetham, B. S.; Anderson, M.; Richards, C.
2014-12-01
In order to mitigate frictional and leakage losses in small scale engines, a compliant engine design is proposed in which the piston in cylinder arrangement is replaced by a flexible cavity. A physics-based nonlinear lumped-parameter model is derived to predict the performance of a prototype engine. The model showed that the engine performance depends on input parameters, such as heat input, heat loss, and load on the engine. A sample simulation for a reference engine with octane fuel/air ratio of 0.043 resulted in an indicated thermal efficiency of 41.2%. For a fixed fuel/air ratio, higher output power is obtained for smaller loads and vice-versa. The heat loss from the engine and the work done on the engine during the intake stroke are found to decrease the indicated thermal efficiency. The ratio of friction work to indicated work in the prototype engine is about 8%, which is smaller in comparison to the traditional reciprocating engines.
The complex spine: the multidimensional system of causal pathways for low-back disorders.
Marras, William S
2012-12-01
The aim of this study was to examine the logic behind the knowledge of low-back problem causal pathways. Low-back pain and low-back disorders (LBDs) continue to represent the major musculoskeletal risk problem in the workplace,with the prevalence and costs of such disorders increasing over time. In recent years, there has been much criticism of the ability of ergonomics methods to control the risk of LBDs. Logical assessment of the systems logic associated with our understanding and prevention of LBDs. Current spine loading as well as spine tolerance research efforts are bringing the field to the point where there is a better systems understanding of the inextricable link between the musculoskeletal system and the cognitive system. Loading is influenced by both the physical environment factors as well as mental demands, whereas tolerances are defined by both physical tissue tolerance and biochemically based tissue sensitivities to pain. However, the logic used in many low-back risk assessment tools may be overly simplistic, given what is understood about causal pathways. Current tools typically assess only load or position in a very cursory manner. Efforts must work toward satisfying both the physical environment and the cognitive environment for the worker if one is to reliably lower the risk of low-back problems. This systems representation of LBD development may serve as a guide to identify gaps in our understanding of LBDs.
Transient Two-Dimensional Analysis of Side Load in Liquid Rocket Engine Nozzles
NASA Technical Reports Server (NTRS)
Wang, Ten-See
2004-01-01
Two-dimensional planar and axisymmetric numerical investigations on the nozzle start-up side load physics were performed. The objective of this study is to develop a computational methodology to identify nozzle side load physics using simplified two-dimensional geometries, in order to come up with a computational strategy to eventually predict the three-dimensional side loads. The computational methodology is based on a multidimensional, finite-volume, viscous, chemically reacting, unstructured-grid, and pressure-based computational fluid dynamics formulation, and a transient inlet condition based on an engine system modeling. The side load physics captured in the low aspect-ratio, two-dimensional planar nozzle include the Coanda effect, afterburning wave, and the associated lip free-shock oscillation. Results of parametric studies indicate that equivalence ratio, combustion and ramp rate affect the side load physics. The side load physics inferred in the high aspect-ratio, axisymmetric nozzle study include the afterburning wave; transition from free-shock to restricted-shock separation, reverting back to free-shock separation, and transforming to restricted-shock separation again; and lip restricted-shock oscillation. The Mach disk loci and wall pressure history studies reconfirm that combustion and the associated thermodynamic properties affect the formation and duration of the asymmetric flow.
Large-Eddy Simulation of Propeller Crashback
NASA Astrophysics Data System (ADS)
Kumar, Praveen; Mahesh, Krishnan
2013-11-01
Crashback is an operating condition to quickly stop a propelled vehicle, where the propeller is rotated in the reverse direction to yield negative thrust. The crashback condition is dominated by the interaction of free stream flow with strong reverse flow. Crashback causes highly unsteady loads and flow separation on blade surface. This study uses Large-Eddy Simulation to predict the highly unsteady flow field in propeller crashback. Results are shown for a stand-alone open propeller, hull-attached open propeller and a ducted propeller. The simulations are compared to experiment, and used to discuss the essential physics behind the unsteady loads. This work is supported by the Office of Naval Research.
Prognostic factors for duration of sickness absence due to musculoskeletal disorders.
Lötters, Freek; Burdorf, Alex
2006-02-01
The purpose of this prospective cohort study with 1-year follow-up was to determine prognostic factors for duration of sickness absence due to musculoskeletal disorders. Workers were included when on sickness absence of 2 to 6 weeks due to musculoskeletal disorders. A self-administered questionnaire was used to collect personal and work-related factors, pain, functional disability, and general health perceptions. Statistical analysis was done with Cox proportional hazard regression with an interaction variable with time for every risk factor of interest. Univariate and multivariate analyses were performed on musculoskeletal disorders and, separately, for low back pain. The main factors that were associated with longer sickness absence were older age, gender, perceived physical workload, and poorer general health for neck, shoulder and upper extremity disorders, and functional disability, sciatica, worker's own perception of the ability of return to work, and chronic complaints for low back pain. Workers with a high perceived physical work load returned to work increasingly slower over time than expected, whereas workers with a high functional disability returned to work increasingly faster over time. High pain intensity is a major prognostic factor for duration of sickness absence, especially in low back pain. The different disease-specific risk profiles for prolonged sickness absence indicate that low back pain and upper extremity disorders need different approaches when applying intervention strategies with the aim of early return to work. The interaction of perceived physical workload with time suggests that perceived physical workload would increasingly hamper return to work and, hence, supports the need for workplace interventions among workers off work for prolonged periods.
Upchurch, Dawn M; Rainisch, Bethany Wexler; Chyu, Laura
2015-01-01
Allostatic load is a useful construct to understand how social and environmental conditions get under the skin to affect health. To date, few studies have examined health-enhancing lifestyle behaviors and their potential benefits in reducing allostatic load. The purpose of this study was to investigate the contributions of leisure time physical activity on level of allostatic load among White, Black, and Mexican American midlife women. Data were from the National Health and Nutrition Examination Survey, 1999 through 2004 (n = 1,680, women ages 40-59). All analyses were weighted. Negative binomial regression was used to model a summative count measure of allostatic load (M = 2.30). Models were also computed to estimate adjusted predicted allostatic load for given levels of physical activity, and by race/ethnicity for each age category (40-44, 45-49, 50-54, 55-59), controlling for other demographics and medication use. Higher levels of physical activity were associated significantly with lower levels of allostatic load, independent of demographics. Compared with White women ages 40 to 44, all other racial/ethnic-by-age groups had significantly higher allostatic load. Higher socioeconomic status was associated with a lower allostatic load. Adjusted prediction models demonstrated associations between greater levels of physical activity and lower allostatic load for all ages and racial/ethnic groups. Our findings suggest physical activity may ameliorate some of the effects of cumulative physiological dysregulation and subsequent disease burden in midlife women. Programs and policies that encourage and promote healthy aging and provide opportunities for a diversity of women to engage in health-enhancing lifestyle practices such as physical activity are recommended. Copyright © 2015 Jacobs Institute of Women's Health. Published by Elsevier Inc. All rights reserved.
Load reduction test method of similarity theory and BP neural networks of large cranes
NASA Astrophysics Data System (ADS)
Yang, Ruigang; Duan, Zhibin; Lu, Yi; Wang, Lei; Xu, Gening
2016-01-01
Static load tests are an important means of supervising and detecting a crane's lift capacity. Due to space restrictions, however, there are difficulties and potential danger when testing large bridge cranes. To solve the loading problems of large-tonnage cranes during testing, an equivalency test is proposed based on the similarity theory and BP neural networks. The maximum stress and displacement of a large bridge crane is tested in small loads, combined with the training neural network of a similar structure crane through stress and displacement data which is collected by a physics simulation progressively loaded to a static load test load within the material scope of work. The maximum stress and displacement of a crane under a static load test load can be predicted through the relationship of stress, displacement, and load. By measuring the stress and displacement of small tonnage weights, the stress and displacement of large loads can be predicted, such as the maximum load capacity, which is 1.25 times the rated capacity. Experimental study shows that the load reduction test method can reflect the lift capacity of large bridge cranes. The load shedding predictive analysis for Sanxia 1200 t bridge crane test data indicates that when the load is 1.25 times the rated lifting capacity, the predicted displacement and actual displacement error is zero. The method solves the problem that lifting capacities are difficult to obtain and testing accidents are easily possible when 1.25 times related weight loads are tested for large tonnage cranes.
Multipactor Physics, Acceleration, and Breakdown in Dielectric-Loaded Accelerating Structures
DOE Office of Scientific and Technical Information (OSTI.GOV)
Fischer, Richard P.; Gold, Steven H.
2016-07-01
The objective of this 3-year program is to study the physics issues associated with rf acceleration in dielectric-loaded accelerating (DLA) structures, with a focus on the key issue of multipactor loading, which has been found to cause very significant rf power loss in DLA structures whenever the rf pulsewidth exceeds the multipactor risetime (~10 ns). The experiments are carried out in the X-band magnicon laboratory at the Naval Research Laboratory (NRL) in collaboration with Argonne National Laboratory (ANL) and Euclid Techlabs LLC, who develop the test structures with support from the DoE SBIR program. There are two main elements inmore » the research program: (1) high-power tests of DLA structures using the magnicon output (20 MW @11.4 GHz), and (2) tests of electron acceleration in DLA structures using relativistic electrons from a compact X-band accelerator. The work during this period has focused on a study of the use of an axial magnetic field to suppress multipactor in DLA structures, with several new high power tests carried out at NRL, and on preparation of the accelerator for the electron acceleration experiments.« less
[Perimenstrual complaints--is this a problem to be handled by occupational medicine physicians].
Makowiec-Dabrowska, Teresa; Sprusińska, Elzbieta; Hanke, Wojciech; Radwan-Włodarczyk, Zyta; Koszada-Włodarczyk, Wiesława
2003-01-01
The aim of the study was to define associations between intensity of perimenstrual complaints, the type of job performed and working conditions, taking also account of non-occupational factors. The study preceding the development of a preventive program was carried out in a group of women employed in work settings different in the character and burden of adverse agents. The group was composed of 142 women, aged 21-45 years, employed in a cosmetics manufacture plant (27%) and a bank (27%), as well as of hospital and ambulatory nurses and auxiliary personnel (50%). A questionnaire on premenstrual and menstrual complaints, working conditions, characteristics of the women and their household duties load was the main tool of the study. The study revealed that about 80% of women experienced premenstrual and about 75% menstrual symptoms, which were strongly intensified in 40% of women. After applying logistic regression, it was found that physical workload and occupational stress were the major occupational risk factors, whereas chronic diseases, age, household duties load and alcohol consumption were the major non-occupational risk factors. The evidenced relationship between complaints and adverse agents typical of the job performed should prompt occupational medicine physicians to more comprehensive analysis of individual jobs in view of reducing occupational load.
NASA Technical Reports Server (NTRS)
Nikityuk, B. A.; Kogan, B. I.; Yermolyev, V. A.; Tindare, L. V.
1980-01-01
Tests were conducted on 100 sexually immature inbred August and Wistar male rats in order to determine the effects hypokinesia, physical load and phenamine on the liver. Weight and linear dimension fell in hypokinesia; total serum protein lowered and aldolase and cholesterol and beta-lipoprotein levels rose. Blood sugar content rose and liver glycogen fell. Interlinear differences of these indices are found. Rehabilitated physical loading against hypokinesia background diminished and at times completely prevented its negative effect. Extent of correction depended on animal species. Evidence of genotypical conditionality of organism adaptation to physical load in hypokinesia was found.
Realization of station for testing asynchronous three-phase motors
NASA Astrophysics Data System (ADS)
Wróbel, A.; Surma, W.
2016-08-01
Nowadays, you cannot imagine the construction and operation of machines without the use of electric motors [13-15]. The proposed position is designed to allow testing of asynchronous three-phase motors. The position consists of a tested engine and the engine running as a load, both engines combined with a mechanical clutch [2]. The value of the load is recorded by measuring shaft created with Strain Gauge Bridge. This concept will allow to study the basic parameters of the engines, visualization motor parameters both vector and scalar controlled, during varying load drive system. In addition, registration during the variable physical parameters of the working electric motor, controlled by a frequency converter or controlled by a contactor will be possible. Position is designed as a teaching and research position to characterize the engines. It will be also possible selection of inverter parameters.
Optical Absorption and Raman Spectroscopy of Multiple Shocked Liquid Benzene to 10 GPa
NASA Astrophysics Data System (ADS)
Root, S.
2005-07-01
Liquid benzene samples were multiply shocked to peak pressures ranging from 3 GPa to 10 GPa to examine physical and chemical changes in benzene. A xenon flashlamp was used to probe the visible spectrum of benzene for loses in transmitted light intensity caused by changes in the electronic structure (absorption) or a possible liquid to solid phase transition (scattering). Raman spectroscopy was used to corroborate transmission measurements by examining changes in the benzene vibrational modes. The C-C symmetric ring breathing mode (992 cm-1), C-H symmetric stretch (3061 cm-1), along with several weaker modes at 607 cm-1, 1178 cm-1, 1586 cm-1, and 1606 cm-1 were monitored during shock loading. An EOS was developed to calculate the temperature of the shock compressed benzene. The present work has demonstrated that liquid benzene remains unchanged during multiple shock loading up to 10 GPa. Work supported by ONR and DOE.
Evaluation of a participatory ergonomic intervention process in kitchen work.
Pehkonen, Irmeli; Takala, Esa-Pekka; Ketola, Ritva; Viikari-Juntura, Eira; Leino-Arjas, Päivi; Hopsu, Leila; Virtanen, Tuija; Haukka, Eija; Holtari-Leino, Merja; Nykyri, Elina; Riihimäki, Hilkka
2009-01-01
We evaluated a participatory ergonomic intervention process applied in 59 municipal kitchens. In groups of three to five kitchens, the workers participated in eight workshops, and generated and evaluated solutions to optimize musculoskeletal load in their work. An ergonomist initiated and supported the process. By the end, 402 changes were implemented. Evaluative data were collected using research diaries, questionnaires, and focus group interviews. The intervention model proved feasible and the participatory approach was mostly experienced as motivating. The workers' knowledge and awareness of ergonomics increased, which improved their ability to tackle ergonomic problems by themselves. The changes in ergonomics were perceived to decrease physical load and improve musculoskeletal health. As hindering factors for implementation, lack of time and motivation, and insufficient financial resources were mentioned. In addition, the workers expressed a wish for more support from the management, technical staff, and ergonomists.
Transient Three-Dimensional Analysis of Side Load in Liquid Rocket Engine Nozzles
NASA Technical Reports Server (NTRS)
Wang, Ten-See
2004-01-01
Three-dimensional numerical investigations on the nozzle start-up side load physics were performed. The objective of this study is to identify the three-dimensional side load physics and to compute the associated aerodynamic side load using an anchored computational methodology. The computational methodology is based on an unstructured-grid, and pressure-based computational fluid dynamics formulation, and a simulated inlet condition based on a system calculation. Finite-rate chemistry was used throughout the study so that combustion effect is always included, and the effect of wall cooling on side load physics is studied. The side load physics captured include the afterburning wave, transition from free- shock to restricted-shock separation, and lip Lambda shock oscillation. With the adiabatic nozzle, free-shock separation reappears after the transition from free-shock separation to restricted-shock separation, and the subsequent flow pattern of the simultaneous free-shock and restricted-shock separations creates a very asymmetric Mach disk flow. With the cooled nozzle, the more symmetric restricted-shock separation persisted throughout the start-up transient after the transition, leading to an overall lower side load than that of the adiabatic nozzle. The tepee structures corresponding to the maximum side load were addressed.
Roja, Zenija; Kalkis, Valdis; Vain, Arved; Kalkis, Henrijs; Eglite, Maija
2006-01-01
Objective This research work is dedicated to occupational health problems caused by ergonomic risks. The research object was road building industry, where workers have to work very intensively, have long work hours, are working in forced/constrained work postures and overstrain during the work specific parts of their bodies. The aim of this study was to evaluate the work heaviness degree and to estimate the muscle fatigue of workers after one week work cycle. The study group consisted of 10 road construction and maintenance workers and 10 pavers aged between 20 and 60 years. Methods Physical load were analyzed by measuring heart rate (HR), work postures (OWAS) and perceived exertion (RPE). Assessments of the muscles strain and functional state (tone) were carried out using myotonometric (MYO) measurements. The reliability of the statistical processing of heart rate monitoring and myotonometry data was determined using correlating analysis. Results This study showed that that road construction and repairing works should be considered as a hard work according to average metabolic energy consumption 8.1 ± 1.5 kcal/min; paving, in its turn, was a moderately hard work according to 7.2 ± 1.1 kcal/min. Several muscle tone levels were identified allowing subdivision of workers into three conditional categories basing on muscle tone and fatigue: I – absolute muscle relaxation and ability to relax; II – a state of equilibrium, when muscles are able to adapt to the work load and are partly able to relax; and III – muscle fatigue and increased tone. It was also found out that the increase of muscle tone and fatigue mainly depend on workers physical preparedness and length of service, and less – on their age. Conclusion We have concluded that a complex ergonomic analysis consisting of heart rate monitoring, assessment of compulsive working postures and myotonometry is appropriate to assess the work heaviness degree and can provide prognosis of occupational pathology or work-related musculoskeletal disorders for the workers under different workload conditions. These results can also be used when deciding on necessary rest time and its periodicity. PMID:16872518
Integral Full Core Multi-Physics PWR Benchmark with Measured Data
DOE Office of Scientific and Technical Information (OSTI.GOV)
Forget, Benoit; Smith, Kord; Kumar, Shikhar
In recent years, the importance of modeling and simulation has been highlighted extensively in the DOE research portfolio with concrete examples in nuclear engineering with the CASL and NEAMS programs. These research efforts and similar efforts worldwide aim at the development of high-fidelity multi-physics analysis tools for the simulation of current and next-generation nuclear power reactors. Like all analysis tools, verification and validation is essential to guarantee proper functioning of the software and methods employed. The current approach relies mainly on the validation of single physic phenomena (e.g. critical experiment, flow loops, etc.) and there is a lack of relevantmore » multiphysics benchmark measurements that are necessary to validate high-fidelity methods being developed today. This work introduces a new multi-cycle full-core Pressurized Water Reactor (PWR) depletion benchmark based on two operational cycles of a commercial nuclear power plant that provides a detailed description of fuel assemblies, burnable absorbers, in-core fission detectors, core loading and re-loading patterns. This benchmark enables analysts to develop extremely detailed reactor core models that can be used for testing and validation of coupled neutron transport, thermal-hydraulics, and fuel isotopic depletion. The benchmark also provides measured reactor data for Hot Zero Power (HZP) physics tests, boron letdown curves, and three-dimensional in-core flux maps from 58 instrumented assemblies. The benchmark description is now available online and has been used by many groups. However, much work remains to be done on the quantification of uncertainties and modeling sensitivities. This work aims to address these deficiencies and make this benchmark a true non-proprietary international benchmark for the validation of high-fidelity tools. This report details the BEAVRS uncertainty quantification for the first two cycle of operations and serves as the final report of the project.« less
Analysis of situation of rural women in the Lublin Region from the aspect of loading with work.
Pawlak, Halina; Maniak, Barbara; Petkowicz, Beata; Kuna-Broniowska, Izabela; Petkowicz, Jacek; Buczaj, Agnieszka
2013-01-01
The objective of the study was recognition of rural women's opinions concerning the degree of heaviness of work activities performed and obtaining the answer to the question: What is the actual level of loading rural women with work? The basic research instrument was a questionnaire form. A representative group of women aged 40-50 were selected for the study because this group had the most complete family structure. The study was conducted among rural women living in the commune of Zwierzyniec. Family size and multi-generationality were analyzed, as well as family members' assistance in household and field activities. The type of work performed was analyzed with consideration of the duration of work and body position while performing this work. Self-reported degree of loading with work on a farm was analyzed, and effective energy expenditure calculated for individual work activities performed by women, based on which the actual degree of loading with work was determined. The respondents generally perceived their loading with work as low. They considered household jobs as not loading with or not exerting any effect on their fatigue and state of health. A very weak statistical relationship was observed between the duration of loading with household jobs and the perceived degree of loading with this work. The Kołmogorov-Smirnov test showed that the evaluations expressed by women concerning the degree of loading with household chores did not depend on time devoted to these work activities. The majority of women similarly evaluated work load, irrespective of the actual degree of loading. Work activities performed in a household were classified according to work load as heavy, medium-heavy and mediocre. Subjective evaluations of work load by rural women considerably differed from the assessment performed using the work time schedule method.
16. BUILDING NO. 445, PHYSICS LAB (FORMERLY GUN BAG LOADING), ...
16. BUILDING NO. 445, PHYSICS LAB (FORMERLY GUN BAG LOADING), INTERIOR, SECOND LEVEL. LOOKING UP AT POWDER AND DISTRIBUTION TUBES. ELEVATOR SHAFT ON LEFT. - Picatinny Arsenal, 400 Area, Gun Bag Loading District, State Route 15 near I-80, Dover, Morris County, NJ
Concurrent working memory load can facilitate selective attention: evidence for specialized load.
Park, Soojin; Kim, Min-Shik; Chun, Marvin M
2007-10-01
Load theory predicts that concurrent working memory load impairs selective attention and increases distractor interference (N. Lavie, A. Hirst, J. W. de Fockert, & E. Viding). Here, the authors present new evidence that the type of concurrent working memory load determines whether load impairs selective attention or not. Working memory load was paired with a same/different matching task that required focusing on targets while ignoring distractors. When working memory items shared the same limited-capacity processing mechanisms with targets in the matching task, distractor interference increased. However, when working memory items shared processing with distractors in the matching task, distractor interference decreased, facilitating target selection. A specialized load account is proposed to describe the dissociable effects of working memory load on selective processing depending on whether the load overlaps with targets or with distractors. (c) 2007 APA
Pramod, P S; Shah, Ruchira; Jayakannan, Manickam
2015-04-21
The present work reports the development of pH and enzyme dual responsive polysaccharide vesicular nano-scaffolds for the administration of doxorubicin via physical loading and polymer-drug conjugation to breast cancer cells. Dextran was suitably modified with a renewable resource 3-pentadecyl phenol unit through imine and aliphatic ester chemical linkages that acted as pH and esterase enzyme stimuli, respectively. These dual responsive polysaccharide derivatives self-organized into 200 ± 10 nm diameter nano-vesicles in water. The water soluble anticancer drug doxorubicin (DOX·HCl) was encapsulated in the hydrophilic pocket to produce core-loaded polysaccharide vesicles whereas chemical conjugation produced DOX anchored at the hydrophobic layer of the dextran nano-vesicles. In vitro studies revealed that about 70-80% of the drug was retained under circulatory conditions at pH = 7.4 and 37 °C. At a low pH of 6.0 to 5.0 and in the presence of esterase; both imine and ester linkages were cleaved instantaneously to release 100% of the loaded drugs. Cytotoxicity assays on Wild Type Mouse Embryonic Fibroblasts (WTMEFs) confirmed the non-toxicity of the newly developed dextran derivatives at up to 500 μg mL(-1) in PBS. MTT assays on fibroblast cells revealed that DOX·HCl loaded nano-vesicles exhibited better killing abilities than DOX conjugated polymer nano-vesicles. Both DOX loaded and DOX conjugated nano-vesicles were found to show significant killing in breast cancer cells (MCF 7). Confocal microscopy images confirmed the uptake of DOX loaded (or conjugated) nano-vesicles by cells compared to free DOX. Thus, the newly developed pH and enzyme dual responsive polysaccharide vesicular assemblies are potential drug vectors for the administration of DOX in both loaded and chemically conjugated forms for the efficient killing of breast cancer cells.
Chhablani, Jay; Nieto, Alejandra; Hou, Huiyuan; Wu, Elizabeth C.; Freeman, William R.; Sailor, Michael J.; Cheng, Lingyun
2013-01-01
Purpose. To test the feasibility of covalent loading of daunorubicin into oxidized porous silicon (OPS) and to evaluate the ocular properties of sustained delivery of daunorubicin in this system. Methods. Porous silicon was heat oxidized and chemically functionalized so that the functional linker on the surface was covalently bonded with daunorubicin. The drug loading rate was determined by thermogravimetric analysis. Release of daunorubicin was confirmed in PBS and excised rabbit vitreous by mass spectrometry. Daunorubicin-loaded OPS particles (3 mg) were intravitreally injected into six rabbits, and ocular properties were evaluated through ophthalmic examinations and histology during a 3-month study. The same OPS was loaded with daunorubicin using physical adsorption and was evaluated similarly as a control for the covalent loading. Results. In the case of covalent loading, 67 ± 10 μg daunorubicin was loaded into each milligram of the particles while 27 ± 10 μg/mg particles were loaded by physical adsorption. Rapid release of daunorubicin was observed in both PBS and excised vitreous (∼75% and ∼18%) from the physical adsorption loading, while less than 1% was released from the covalently loaded particles. Following intravitreal injection, the covalently loaded particles demonstrated a sustained degradation of OPS with drug release for 3 months without evidence of toxicity; physical adsorption loading revealed a complete release within 2 weeks and localized retinal toxicity due to high daunorubicin concentration. Conclusions. OPS with covalently loaded daunorubicin demonstrated sustained intravitreal drug release without ocular toxicity, which may be useful to inhibit unwanted intraocular proliferation. PMID:23322571
Optimising technical skills and physical loading in small-sided basketball games.
Klusemann, Markus J; Pyne, David B; Foster, Carl; Drinkwater, Eric J
2012-01-01
Differences in physiological, physical, and technical demands of small-sided basketball games related to the number of players, court size, and work-to-rest ratios are not well characterised. A controlled trial was conducted to compare the influence of number of players (2v2/4v4), court size (half/full court) and work-to-rest ratios (4x2.5 min/2x5 min) on the demands of small-sided games. Sixteen elite male and female junior players (aged 15-19 years) completed eight variations of a small-sided game in randomised order over a six-week period. Heart rate responses and rating of perceived exertion (RPE) were measured to assess the physiological load. Movement patterns and technical elements were assessed by video analysis. There were ∼60% more technical elements in 2v2 and ∼20% more in half court games. Heart rate (86 ± 4% & 83 ± 5% of maximum; mean ± SD) and RPE (8 ± 2 & 6 ± 2; scale 1-10) were moderately higher in 2v2 than 4v4 small-sided games, respectively. The 2v2 format elicited substantially more sprints (36 ±12%; mean ±90% confidence limits) and high intensity shuffling (75 ±17%) than 4v4. Full court games required substantially more jogging (9 ±6%) compared to half court games. Fewer players in small-sided basketball games substantially increases the technical, physiological and physical demands.
NASA Astrophysics Data System (ADS)
Javernick, Luke; Redolfi, Marco; Bertoldi, Walter
2018-05-01
New data collection techniques offer numerical modelers the ability to gather and utilize high quality data sets with high spatial and temporal resolution. Such data sets are currently needed for calibration, verification, and to fuel future model development, particularly morphological simulations. This study explores the use of high quality spatial and temporal data sets of observed bed load transport in braided river flume experiments to evaluate the ability of a two-dimensional model, Delft3D, to predict bed load transport. This study uses a fixed bed model configuration and examines the model's shear stress calculations, which are the foundation to predict the sediment fluxes necessary for morphological simulations. The evaluation is conducted for three flow rates, and model setup used highly accurate Structure-from-Motion (SfM) topography and discharge boundary conditions. The model was hydraulically calibrated using bed roughness, and performance was evaluated based on depth and inundation agreement. Model bed load performance was evaluated in terms of critical shear stress exceedance area compared to maps of observed bed mobility in a flume. Following the standard hydraulic calibration, bed load performance was tested for sensitivity to horizontal eddy viscosity parameterization and bed morphology updating. Simulations produced depth errors equal to the SfM inherent errors, inundation agreement of 77-85%, and critical shear stress exceedance in agreement with 49-68% of the observed active area. This study provides insight into the ability of physically based, two-dimensional simulations to accurately predict bed load as well as the effects of horizontal eddy viscosity and bed updating. Further, this study highlights how using high spatial and temporal data to capture the physical processes at work during flume experiments can help to improve morphological modeling.
Impacting load control of floating supported friction plate and its experimental verification
NASA Astrophysics Data System (ADS)
Ning, Keyan; Wang, Yu; Huang, Dingchuan; Yin, Lei
2017-05-01
Friction plates are key components in automobile transmission system. Unfortunately, due to the tough working condition i.e. high impact, high temperature, fracture and plastic deformation are easily observed in friction plates. In order to reduce the impact load and increase the impact resistance and life span of the friction plate. This paper presents a variable damping design method and structure, by punching holes in the key position of the friction plate and filling it with damping materials, the impact load of the floating support friction plate can be controlled. Simulation is applied to study the effect of the position and number of damping holes on tooth root stress. Furthermore, physic test was designed and conducted to validate the correctness and effectiveness of the proposed method. Test result shows that the impact load of the new structure is reduced by 40% and its fatigue life is 4.7 times larger. The new structure provides a new way for floating supported friction plates design.
Autonomous Cryogenics Loading Operations Simulation Software: Knowledgebase Autonomous Test Engineer
NASA Technical Reports Server (NTRS)
Wehner, Walter S.
2012-01-01
The Simulation Software, KATE (Knowledgebase Autonomous Test Engineer), is used to demonstrate the automatic identification of faults in a system. The ACLO (Autonomous Cryogenics Loading Operation) project uses KATE to monitor and find faults in the loading of the cryogenics int o a vehicle fuel tank. The KATE software interfaces with the IHM (Integrated Health Management) systems bus to communicate with other systems that are part of ACLO. One system that KATE uses the IHM bus to communicate with is AIS (Advanced Inspection System). KATE will send messages to AIS when there is a detected anomaly. These messages include visual inspection of specific valves, pressure gauges and control messages to have AIS open or close manual valves. My goals include implementing the connection to the IHM bus within KATE and for the AIS project. I will also be working on implementing changes to KATE's Ul and implementing the physics objects in KATE that will model portions of the cryogenics loading operation.
Vincent, Julie; Forquet, Nicolas; Molle, Pascal; Wisniewski, Christelle
2012-07-01
This work was designed to study the hydraulic properties of sludge deposit, focusing on the impact of operating conditions (i.e. loads and feeding frequencies) on air entrance (aerobic mineralization optimization) into the sludge deposit. The studied sludge deposits came from six 2m(2) pilot-scale SDRBs that had been in operation for 50 months with three different loads of 30, 50, and 70 kg of SSm(-2) y(-1). Two influents were assessed (i.e. activated sludge and septage) presenting different characteristics (i.e. pollutant contents, physical properties...). Two experimental approaches were employed based on establishing the water retention curve (capillary pressure versus volumetric water content) and the hydrotextural diagram to determine the hydraulic properties of sludge deposit. The study obtained valuable information for optimizing operating conditions, specifically for efficient management of loading frequency to optimize aerobic conditions within the sludge deposit. Copyright © 2012 Elsevier Ltd. All rights reserved.
Schapschröer, M; Baker, J; Schorer, J
2016-06-01
Studies examining experts' superiority within domain-specific structured pattern recall tasks have typically had athletes perform them at rest, which is far different from how they are executed in their sport. The aim of this study was to investigate whether performing these tasks under different physical exercise intensities influenced pattern recall results of experts, advanced and novices. In two experiments, 68 participants (experiment 1: n = 33; experiment 2: n = 35) were tested using a handball-specific pattern recall task both at rest and during physical exercise. Physical exercises of 60 % heart rate reserve (constant workload: experiment 1) and of 86.5-90 % HRmax (handball-specific interval load: experiment 2) were induced. Results of both experiments revealed significant group differences with experts recalling patterns more accurately than novices but no significant within-subject differences for the two conditions and no interaction between both factors. Our findings replicate prior research concerning perceptual-cognitive expertise in structured specific pattern recall tasks. However, the lack of intergroup differences between the two conditions or interactions was surprising, suggesting sport-specific pattern recall skill is robust to changes in exercise stimuli. Future work is needed to further examine the impact of "physiological specificity" on perceptual-cognitive expertise.
Physical, anthropometrical, and body composition characteristics of workers at Kennedy Space Center
NASA Technical Reports Server (NTRS)
Lasley, M. L.
1985-01-01
At the Kennedy Space Center, workers are often exposed to cardiovascular and muscular stress in job-related activities which may require a high level of physical fitness in order to safely complete the work task. Similar tasks will be performed at other launch and landing facilities and in space for the Space Station. One such category includes workers who handle toxic propellants and must wear Self-Contained Atmospheric Protective Ensembles (SCAPE) that can weigh 56 lbs. with the air pack. These suits provide a significant physical challenge to many of the workers in terms of carrying this load while moving about and performing work. Furthermore, under some conditions, there is a significant thermal stress. The physical characteristics of these workers are, therefore, of consequence. The purpose of this study was to analyze the anthropometry, body composition, strength, power, endurance, flexibility, aerobic fitness, and blood variables of a representative sample of male KSC SCAPE workers and to compare them with characteristics of other male workers at KSC (total population N=110). Three separate comparisons were made.
Predictors of back disorder among Almeda textile factory workers, North Ethiopia.
Abraha, Teklehaymanot Huluf; Demoz, Asmelash Tekie; Moges, Haimanot Gebrehiwot; Ahmmed, Ansha Nega
2018-05-16
To guide the development of targeted interventions for the prevention of work-related back pain, this manuscript estimates the prevalence of back pain and its association with a variety of risk factors among Almeda textile factory production works from March to April 2015. An institutional-based cross-sectional study was carried out in Almeda textile factory, North Ethiopia. Randomly selected workers were administered a structured questionnaire about their socio-economic status, lifestyle, working conditions, back pain and selected risk factors. The data was entered to Epi Info 3.5.4 version and analyzed using SPSS version 16. Descriptive statistics were done to characterize the study participants. Bivariate and multiple logistic regressions were fitted to control confounding variables. Adjusted odds ratio with 95% confidence intervals was computed. The prevalence of work-related musculoskeletal disorders was 53.1%. Gender, age, years of service, lack of physical activity, unavailability of adjustable chair, work-load and poor light were significantly associated with increased risk of back pain. The high prevalence of work-related back pain disorder implies that; habit of doing physical exercise, availing adjustable chair and light at the working place, are key issues which require specific interventions.
Childhood abuse and depression in adulthood: The mediating role of allostatic load.
Scheuer, Sandra; Wiggert, Nicole; Brückl, Tanja Maria; Awaloff, Yvonne; Uhr, Manfred; Lucae, Susanne; Kloiber, Stefan; Holsboer, Florian; Ising, Marcus; Wilhelm, Frank H
2018-04-22
Traumatic experiences during childhood are considered a major risk factor for depression in adulthood. Childhood trauma may induce physiological dysregulation with long-term effects of increased allostatic load until adulthood, which may lead to depression. Thus, our aim was to investigate whether allostatic load - which represents a multi-system measure of physiological dysregulation - mediates the association between childhood trauma and adult depression. The study sample consisted of 324 depressed inpatients participating in the Munich Antidepressant Response Signature (MARS) project and 261 mentally healthy control participants. The mediation analysis using a case-control approach included childhood trauma, i.e., physical and sexual abuse, as predictor variables and an allostatic load index comprised of 12 stress-related biomarkers as mediator. Age and sex were included as covariates. Mediation analyses revealed that the influence of physical abuse, but not sexual abuse, during childhood on depression in adulthood was mediated by allostatic load. This effect was moderated by age: particularly young (18-42 years) and middle-aged (43-54 years) adults with a history of physical abuse during childhood exhibited high allostatic load, which in turn was associated with increased rates of depression, but this was not the case for older participants (55-81 years). Results support the theoretical assumption of allostatic load mediating the effect of physical abuse during childhood on depression in adulthood. This predominantly holds for younger participants, while depression in older participants was independent of physical abuse and allostatic load. The effect of sexual abuse on depression, however, was not mediated by allostatic load. Identifying allostatic load biomarkers prospectively in the developmental course of depression is an important target for future research. Copyright © 2018 Elsevier Ltd. All rights reserved.
Job satisfaction among academic coordinators of clinical education in physical therapy.
Harris, M J; Fogel, M; Blacconiere, M
1987-06-01
The Academic Coordinator of Clinical Education is the physical therapy faculty member who is responsible for the clinical component of the curriculum. The responsibilities involved in the ACCE's job are such that ACCEs seem to be at risk for job dissatisfaction and burnout. The purpose of this descriptive study was to investigate the levels and patterns of job satisfaction among ACCEs in physical therapy. A questionnaire, including a 32-item job satisfaction inventory, was sent to the ACCE at each accredited entry-level education program for physical therapists and physical therapist assistants (N = 169). One hundred twelve (66.3%) responses were received and analyzed. Demographic characteristics of the respondents are reported. The results of the study showed that ACCEs, in general, expressed low levels of occupational dissatisfaction and burnout. Satisfaction with the aspects of the job involving self-esteem, achievement, and creativity seems to outweight dissatisfaction with the time available, the work load, and organizational efficiency. Those ACCEs with doctoral degrees expressed the highest levels of dissatisfaction and burnout. Those ACCEs working in entry-level master's degree programs expressed the lowest level of dissatisfaction; those in tenure-track positions expressed the lowest level of burnout. Factors contributing to job satisfaction and dissatisfaction are discussed.
Fitness Load and Exercise Time in Secondary Physical Education Classes.
ERIC Educational Resources Information Center
Li, Xiao Jun; Dunham, Paul, Jr.
1993-01-01
Investigates the effect of secondary school physical education on fitness load: the product of the mean heart rate above threshold (144 bpm) and the time duration of heart rate above that threshold. Highly and moderately skilled students achieved fitness load more frequently than their lower skilled colleagues. (GLR)
10. BUILDING NO. 445, PHYSICS LAB (FORMERLY GUN BAG LOADING), ...
10. BUILDING NO. 445, PHYSICS LAB (FORMERLY GUN BAG LOADING), LOOKING AT SOUTHEAST CORNER. BUILDING NO. 332, CHANGE HOUSE, IN RIGHT BACKGROUND; BUILDING NO. 445-F, MAGAZINE, IN LEFT BACKGROUND. - Picatinny Arsenal, 400 Area, Gun Bag Loading District, State Route 15 near I-80, Dover, Morris County, NJ
El-Sayed, Marwa M; Hussein, Amal K; Sarhan, Hatem A; Mansour, Heba F
2017-06-01
The present work aimed to prolong the contact time of flurbiprofen (FBP) in the ocular tissue to improve the drug anti-inflammatory activity. Different niosome systems were fabricated adopting thin-film hydration technique and using the nonionic surfactant Span 60. The morphology of the prepared niosomes was characterized by scanning electron microscopy (SEM). Physical characterization by differential scanning calorimetry, X-ray powder diffraction and Fourier transform infrared spectroscopy were conducted for the optimized formula (F5) that was selected on the basis of percent entrapment efficiency, vesicular size and total lipid content. F5 was formulated as 1% w/w Carpobol 934 gel. Pharmacokinetic parameters of FBP were investigated following ocular administration of F5-loaded gel system, F5 niosome dispersion or the corresponding FBP ocular drops to albino rabbits dispersion. Anti-inflamatory effect of F5-loaded carbopol gel was investigated by histopathological examination of the corneal tissue before and after the treatment of inflamed rabbit eye with the system. Results showed that cholesterol content, surfactant type. and total lipid contents had an apparent impact on the vesicle size of the formulated niosomes. Physical characterization revealed reduced drug crystallinity and incidence of interaction with other niosome contents. F5-loaded gel showed higher C max , area under the curve (AUC 0-12 ), and thus higher ocular bioavailability than those of the corresponding FBP ocular solution. F5-loaded gel showed a promising rapid anti-inflammatory effect in the inflamed rabbit eye. These findings will eradicate the necessity for frequent ocular drug instillation and thus, improve patient compliance.
2010-01-01
Background The two primary objectives of this study were to the assess consultation load of occupational health physicians (OHPs), and their difficulties and needs with regard to their sickness certification tasks in sick-listed employees with severe medical unexplained physical symptoms (MUPS). Third objective was to determine which disease-, patient-, doctor- and practice-related factors are associated with the difficulties and needs of the OHPs. Methods In this cross-sectional study, 43 participating OHPs from 5 group practices assessed 489 sick-listed employees with and without severe MUPS. The OHPs filled in a questionnaire about difficulties concerning sickness certification tasks, consultation time, their needs with regard to consultation with or referral to a psychiatrist or psychologist, and communication with GPs. The OHPs also completed a questionnaire about their personal characteristics. Results OHPs only experienced task difficulties in employees with severe MUPS in relation to their communication with the treating physician. This only occured in cases in which the OHP attributed the physical symptoms to somatoform causes. If they attributed the physical symptoms to mental causes, the OHPs reported a need to consultate a psychiatrist about the diagnosis and treatment. Conclusions OHPs experience few difficulties with their sickness certification tasks and consultation load concerning employees with severe MUPS. However, they encounter problems if the diagnostic uncertainties of the treating physician interfere with the return to work process. OHPs have a need for psychiatric expertise whenever they are uncertain about the psychiatric causes of a delayed return to work process. We recommend further training programs for OHPs. They should also have more opportunity for consultation and referral to a psychiatrist, and their communication with treating physicians should be improved. PMID:21059232
NASA Astrophysics Data System (ADS)
Farooq, Umar; Myler, Peter
This work is concerned with physical testing of carbon fibrous laminated composite panels with low velocity drop-weight impacts from flat and round nose impactors. Eight, sixteen, and twenty-four ply panels were considered. Non-destructive damage inspections of tested specimens were conducted to approximate impact-induced damage. Recorded data were correlated to load-time, load-deflection, and energy-time history plots to interpret impact induced damage. Data filtering techniques were also applied to the noisy data that unavoidably generate due to limitations of testing and logging systems. Built-in, statistical, and numerical filters effectively predicted load thresholds for eight and sixteen ply laminates. However, flat nose impact of twenty-four ply laminates produced clipped data that can only be de-noised involving oscillatory algorithms. Data filtering and extrapolation of such data have received rare attention in the literature that needs to be investigated. The present work demonstrated filtering and extrapolation of the clipped data using Fast Fourier Convolution algorithm to predict load thresholds. Selected results were compared to the damage zones identified with C-scan and acceptable agreements have been observed. Based on the results it is proposed that use of advanced data filtering and analysis methods to data collected by the available resources has effectively enhanced data interpretations without resorting to additional resources. The methodology could be useful for efficient and reliable data analysis and impact-induced damage prediction of similar cases' data.
Transient Three-Dimensional Analysis of Nozzle Side Load in Regeneratively Cooled Engines
NASA Technical Reports Server (NTRS)
Wang, Ten-See
2005-01-01
Three-dimensional numerical investigations on the start-up side load physics for a regeneratively cooled, high-aspect-ratio nozzle were performed. The objectives of this study are to identify the three-dimensional side load physics and to compute the associated aerodynamic side load using an anchored computational methodology. The computational methodology is based on an unstructured-grid, pressure-based computational fluid dynamics formulation, and a transient inlet condition based on an engine system simulation. Computations were performed for both the adiabatic and cooled walls in order to understand the effect of boundary conditions. Finite-rate chemistry was used throughout the study so that combustion effect is always included. The results show that three types of shock evolution are responsible for side loads: generation of combustion wave; transitions among free-shock separation, restricted-shock separation, and simultaneous free-shock and restricted shock separations; along with oscillation of shocks across the lip. Wall boundary conditions drastically affect the computed side load physics: the adiabatic nozzle prefers free-shock separation while the cooled nozzle favors restricted-shock separation, resulting in higher peak side load for the cooled nozzle than that of the adiabatic nozzle. By comparing the computed physics with those of test observations, it is concluded that cooled wall is a more realistic boundary condition, and the oscillation of the restricted-shock separation flow pattern across the lip along with its associated tangential shock motion are the dominant side load physics for a regeneratively cooled, high aspect-ratio rocket engine.
Pedersen, D M; Clark, J A; Johns, R E; White, G L; Hoffman, S
1989-01-01
In this study the authors investigate the percentage of mismatch between job demands and worker physical capacity in Utah National Guard mechanics. This population had demonstrated a higher incidence of low back trouble than other job descriptions reviewed. The authors utilized onsite still and videotape photography and a computerized biomechanical strength prediction model to assess loads on the lumbosacral spine due to various job tasks. Job demands were then compared to the actual physical capacity of the individual workers based on static strength testing in job-related positions. A load cell on the testing apparatus entered the force generated into a computer which averaged the force of the last three seconds of a five-second lift. It was determined that as much as a 38% mismatch existed within this population for some job tasks which these workers were exposed to. Suggestions for preventing job-related low back cumulative trauma disorders are presented, including: engineering redesign, worker selection programs, work hardening, and others.
Work-Load Planning for Navy Stock Points
1990-12-01
capacity. 2. The level of utilization of a non -bottleneck is not determined by its own potential, but by some other constraint in the system. 3...the amounts to carry based on customer demands and non -demand based requirements II. Basic Operations A. Determines which items to carry in inventory...storage, physical inventory, issue, transportation, and 8 control of material. The focus was to be primarily on the relationships among functions in
Activity-rest schedules in physically demanding work and the variation of responses with age.
Kakarot, Nadine; Mueller, Friedrich; Bassarak, Claudia
2012-01-01
Workers in physically demanding occupations require work breaks to recover from exertion. In a laboratory setting, we investigated the impact of ergometer cycling for 7 h in two conditions with an identical total break time but with two different activity-rest schedules. We hypothesised that more frequent but shorter breaks lead to less psychophysical strain and its effects than do less frequent but longer breaks, particularly for older workers. Twenty-nine participants representing three different age groups were tested in both conditions. Heart rate, perceived exertion/tension and feelings of fatigue were assessed and used as dependent variables. Results indicate no general activity-rest differences as well as no age-related differences of break effects under the condition of subjectively equal straining load. However, heart rate was found to be lower at some measurement points in the frequent-short-break condition and perceived exertion was lower in the infrequent-long-break condition. Design of activity-rest schedules in physically demanding occupations is a key issue in the prevention of strain and hence of interest to ergonomists. Our study suggests that breaks during physically demanding work have the same effect if they are frequent and short or infrequent and long, regardless of age.
Fussell, Andrew L; Mah, Pei Ting; Offerhaus, Herman; Niemi, Sanna-Mari; Salonen, Jarno; Santos, Hélder A; Strachan, Clare
2014-11-01
This study reports the use of variants of coherent anti-Stokes Raman scattering (CARS) microscopy as a novel method for improved physicochemical characterization of drug-loaded silica particles. Ordered mesoporous silica is a biomaterial that can be loaded to carry a number of biochemicals, including poorly water-soluble drugs, by allowing the incorporation of drug into nanometer-sized pores. In this work, the loading of two poorly water-soluble model drugs, itraconazole and griseofulvin, in MCM-41 silica microparticles is characterized qualitatively, using the novel approach of CARS microscopy, which has advantages over other analytical approaches used to date and is non-destructive, rapid, label free, confocal and has chemical and physical specificity. The study investigated the effect of two solvent-based loading methods, namely immersion and rotary evaporation, and microparticle size on the three-dimensional (3-D) distribution of the two loaded drugs. Additionally, hyperspectral CARS microscopy was used to confirm the amorphous nature of the loaded drugs. Z-stacked CARS microscopy suggested that the drug, but not the loading method or particle size range, affected 3-D drug distribution. Hyperspectral CARS confirmed that the drug loaded in the MCM-41 silica microparticles was in an amorphous form. The results show that CARS microscopy and hyperspectral CARS microscopy can be used to provide further insights into the structural nature of loaded mesoporous silica microparticles as biomaterials. Copyright © 2014 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
Components of working memory and visual selective attention.
Burnham, Bryan R; Sabia, Matthew; Langan, Catherine
2014-02-01
Load theory (Lavie, N., Hirst, A., De Fockert, J. W., & Viding, E. [2004]. Load theory of selective attention and cognitive control. Journal of Experimental Psychology: General, 133, 339-354.) proposes that control of attention depends on the amount and type of load that is imposed by current processing. Specifically, perceptual load should lead to efficient distractor rejection, whereas working memory load (dual-task coordination) should hinder distractor rejection. Studies support load theory's prediction that working memory load will lead to larger distractor effects; however, these studies used secondary tasks that required only verbal working memory and the central executive. The present study examined which other working memory components (visual, spatial, and phonological) influence visual selective attention. Subjects completed an attentional capture task alone (single-task) or while engaged in a working memory task (dual-task). Results showed that along with the central executive, visual and spatial working memory influenced selective attention, but phonological working memory did not. Specifically, attentional capture was larger when visual or spatial working memory was loaded, but phonological working memory load did not affect attentional capture. The results are consistent with load theory and suggest specific components of working memory influence visual selective attention. PsycINFO Database Record (c) 2014 APA, all rights reserved.
Ghunmi, Lina Abu; Zeeman, Grietje; van Lier, Jules; Fayyed, Manar
2008-01-01
The objective of this work is to assess the potentials and requirements for grey water reuse in Jordan. The results revealed that urban, rural and dormitory grey water production rate and concentration of TS, BOD(5), COD and pathogens varied between 18-66 L cap(-1)d(-1), 848-1,919, 200-1,056, and 560-2,568 mg L(-1) and 6.9E2-2.7E5 CFU mL(-1), respectively. The grey water compromises 64 to 85% of the total water flow in the rural and urban areas. Storing grey water is inevitable to meet reuse requirements in terms of volume and timing. All the studied grey waters need treatment, in terms of solids, BOD(5), COD and pathogens, before storage and reuse. Storage and physical treatment, as a pretreatment step should be avoided, since it produces unstable effluents and non-stabilized sludge. However, extensive biological treatment can combine storage and physical treatments. Furthermore, a batch-fed biological treatment system combining anaerobic and aerobic processes copes with the fluctuations in the hydrographs and pollutographs as well as the present nutrients. The inorganic content of grey water in Jordan is about drinking water quality and does not need treatment. Moreover, the grey water SAR values were 3-7, revealing that the concentrations of monovalent and divalent cations comply with agricultural demand in Jordan. The observed patterns in the hydrographs and pollutographs showed that the hydraulic load could be used for the design of both physical and biological treatment units for dormitories and hotels. For family houses the hydraulic load was identified as the key design parameter for physical treatment units and the organic load is the key design parameter for biological treatment units. Copyright IWA Publishing 2008.
Il'chemko, I N; Tubol, I B; Shal'nova, S A; Zinenko, G M; Likov, A F
1983-01-01
In a cross-sectional epidemiologic study of schoolchildren aged 11-17 years, the cardiac work index at exercise was found to be higher in schoolchildren with arterial hypertension (AH) and excess body weight than in the control group. The duration of an exercise test was similar in the two groups. The higher cardiac work index at exercise may be explained by considerably higher systolic blood pressure in schoolchildren with AH and by higher heart rates in those with excess body weight.
Nittayacharn, Pinunta; Nasongkla, Norased
2017-07-01
The objective of this work was to develop self-forming doxorubicin-loaded polymeric depots as an injectable drug delivery system for liver cancer chemotherapy and studied the release profiles of doxorubicin (Dox) from different depot formulations. Tri-block copolymers of poly(ε-caprolactone), poly(D,L-lactide) and poly(ethylene glycol) named PLECs were successfully used as a biodegradable material to encapsulate Dox as the injectable local drug delivery system. Depot formation and encapsulation efficiency of these depots were evaluated. Results show that depots could be formed and encapsulate Dox with high drug loading content. For the release study, drug loading content (10, 15 and 20% w/w) and polymer concentration (25, 30, and 35% w/v) were varied. It could be observed that the burst release occurred within 1-2 days and this burst release could be reduced by physical mixing of hydroxypropyl-beta-cyclodextrin (HP-β-CD) into the depot system. The degradation at the surface and cross-section of the depots were examined by Scanning Electron Microscope (SEM). In addition, cytotoxicity of Dox-loaded depots and blank depots were tested against human liver cancer cell lines (HepG2). Dox released from depots significantly exhibited potent cytotoxic effect against HepG2 cell line compared to that of blank depots. Results from this study reveals an important insight in the development of injectable drug delivery system for liver cancer chemotherapy. Schematic diagram of self-forming doxorubicin-loaded polymeric depots as an injectable drug delivery system and in vitro characterizations. (a) Dox-loaded PLEC depots could be formed with more than 90% of sustained-release Dox at 25% polymer concentration and 20% Dox-loading content. The burst release occurred within 1-2 days and could be reduced by physical mixing of hydroxypropyl-beta-cyclodextrin (HP-β-CD) into the depot system. (b) Dox released from depots significantly exhibited potent cytotoxic effect against human liver cancer cell lines (HepG2 cell line) compared to that of blank depots. (c) Dox-loaded depots showed bulk erosion with hollow core at day 60.
Factors related to successful job reintegration of people with a lower limb amputation.
Schoppen, T; Boonstra, A; Groothoff, J W; van Sonderen, E; Göeken, L N; Eisma, W H
2001-10-01
To study demographically, amputation-, and employment-related factors that show a relationship to successful job reintegration of patients after lower limb amputation. Cross-sectional study. University hospital. Subjects had an acquired unilateral major amputation of the lower limb at least 2 years before, were aged 18 to 60 years (mean, 46yr), and were living in the Netherlands. All 322 patients were working at the time of amputation and were recruited from orthopedic workshops. Questionnaires sent to subjects to self-report (1) demographic and amputation information and (2) job characteristics and readjustment postamputation. Questionnaire sent to rehabilitation specialists to assess physical work load. Demographically related (age, gender); amputation-related (comorbidity; reason and level; problems with stump, pain, prosthesis use and problems, mobility, rehabilitation); and employment-related (education, physical workload) information about the success of job reintegration. Job reintegration was successful in 79% and unsuccessful in 21% of the amputees. Age at the time of amputation, wearing comfort of the prosthesis, and education level were significant indicators of successful job reintegration. Subjects with physically demanding jobs who changed type of job before and after the amputation more often successfully returned to work than subjects who tried to stay at the same type of job. Older patients with a low education level and problems with the wearing comfort of the prosthesis are a population at risk who require special attention during the rehabilitation process in order to return to work. Lowering the physical workload by changing to another type of work enhances the chance of successful reintegration. Copyright 2001 by the American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation
The effects of load carriage on joint work at different running velocities.
Liew, Bernard X W; Morris, Susan; Netto, Kevin
2016-10-03
Running with load carriage has become increasingly prevalent in sport, as well as many field-based occupations. However, the "sources" of mechanical work during load carriage running are not yet completely understood. The purpose of this study was to determine the influence of load magnitudes on the mechanical joint work during running, across different velocities. Thirty-one participants performed overground running at three load magnitudes (0%, 10%, 20% body weight), and at three velocities (3, 4, 5m/s). Three dimensional motion capture was performed, with synchronised force plate data captured. Inverse dynamics was used to quantify joint work in the stance phase of running. Joint work was normalized to a unit proportion of body weight and leg length (one dimensionless work unit=532.45J). Load significantly increased total joint work and total positive work and this effect was greater at faster velocities. Load carriage increased ankle positive work (β coefficient=rate of 6.95×10 -4 unit work per 1% BW carried), and knee positive (β=1.12×10 -3 unit) and negative work (β=-2.47×10 -4 unit), and hip negative work (β=-7.79×10 -4 unit). Load carriage reduced hip positive work and this effect was smaller at faster velocities. Inter-joint redistribution did not contribute significantly to altered mechanical work within the spectrum of load and velocity investigated. Hence, the ankle joint contributed to the greatest extent in work production, whilst that of the knee contributed to the greatest extent to work absorption when running with load. Copyright © 2016 Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Wang, Guiji; Chen, Xuemiao; Cai, Jintao; Zhang, Xuping; Chong, Tao; Luo, Binqiang; Zhao, Jianheng; Sun, Chengwei; Tan, Fuli; Liu, Cangli; Wu, Gang
2016-06-01
A high current pulsed power generator CQ-3-MMAF (Multi-Modules Assembly Facility, MMAF) was developed for material dynamics experiments under ramp wave and shock loadings at the Institute of Fluid Physics (IFP), which can deliver 3 MA peak current to a strip-line load. The rise time of the current is 470 ns (10%-90%). Different from the previous CQ-4 at IFP, the CQ-3-MMAF energy is transmitted by hundreds of co-axial high voltage cables with a low impedance of 18.6 mΩ and low loss, and then hundreds of cables are reduced and converted to tens of cables into a vacuum chamber by a cable connector, and connected with a pair of parallel metallic plates insulated by Kapton films. It is composed of 32 capacitor and switch modules in parallel. The electrical parameters in short circuit are with a capacitance of 19.2 μF, an inductance of 11.7 nH, a resistance of 4.3 mΩ, and working charging voltage of 60 kV-90 kV. It can be run safely and stable when charged from 60 kV to 90 kV. The vacuum of loading chamber can be up to 10-2 Pa, and the current waveforms can be shaped by discharging in time sequences of four groups of capacitor and switch modules. CQ-3-MMAF is an adaptive machine with lower maintenance because of its modularization design. The COMSOL Multi-physics® code is used to optimize the structure of some key components and calculate their structural inductance for designs, such as gas switches and cable connectors. Some ramp wave loading experiments were conducted to check and examine the performances of CQ-3-MMAF. Two copper flyer plates were accelerated to about 3.5 km/s in one shot when the working voltage was charged to 70 kV. The velocity histories agree very well. The dynamic experiments of some polymer bonded explosives and phase transition of tin under ramp wave loadings were also conducted. The experimental data show that CQ-3-MMAF can be used to do material dynamics experiments in high rate and low cost shots. Based on this design concept, the peak current of new generators can be increased to 5-6 MA and about 100 GPa ramp stress can be produced on the metallic samples for high pressure physics, and a conceptual design of CQ-5-MMAF was given.
Wang, Guiji; Chen, Xuemiao; Cai, Jintao; Zhang, Xuping; Chong, Tao; Luo, Binqiang; Zhao, Jianheng; Sun, Chengwei; Tan, Fuli; Liu, Cangli; Wu, Gang
2016-06-01
A high current pulsed power generator CQ-3-MMAF (Multi-Modules Assembly Facility, MMAF) was developed for material dynamics experiments under ramp wave and shock loadings at the Institute of Fluid Physics (IFP), which can deliver 3 MA peak current to a strip-line load. The rise time of the current is 470 ns (10%-90%). Different from the previous CQ-4 at IFP, the CQ-3-MMAF energy is transmitted by hundreds of co-axial high voltage cables with a low impedance of 18.6 mΩ and low loss, and then hundreds of cables are reduced and converted to tens of cables into a vacuum chamber by a cable connector, and connected with a pair of parallel metallic plates insulated by Kapton films. It is composed of 32 capacitor and switch modules in parallel. The electrical parameters in short circuit are with a capacitance of 19.2 μF, an inductance of 11.7 nH, a resistance of 4.3 mΩ, and working charging voltage of 60 kV-90 kV. It can be run safely and stable when charged from 60 kV to 90 kV. The vacuum of loading chamber can be up to 10(-2) Pa, and the current waveforms can be shaped by discharging in time sequences of four groups of capacitor and switch modules. CQ-3-MMAF is an adaptive machine with lower maintenance because of its modularization design. The COMSOL Multi-physics® code is used to optimize the structure of some key components and calculate their structural inductance for designs, such as gas switches and cable connectors. Some ramp wave loading experiments were conducted to check and examine the performances of CQ-3-MMAF. Two copper flyer plates were accelerated to about 3.5 km/s in one shot when the working voltage was charged to 70 kV. The velocity histories agree very well. The dynamic experiments of some polymer bonded explosives and phase transition of tin under ramp wave loadings were also conducted. The experimental data show that CQ-3-MMAF can be used to do material dynamics experiments in high rate and low cost shots. Based on this design concept, the peak current of new generators can be increased to 5-6 MA and about 100 GPa ramp stress can be produced on the metallic samples for high pressure physics, and a conceptual design of CQ-5-MMAF was given.
[New methods for determining the relative load due to physical effort of the human body].
Szubert, Józef; Szubert, Sławomir; Koszada-Włodarczyk, Wiesława; Bortkiewicz, Alicja
2014-01-01
The relative physical load (% VO2max) is the quotient of oxygen uptake (Vo2) during physical effort and maximum oxygen uptake (VO2max) by the human body. For this purpose the stress test must be performed. The relative load shows a high correlation with minute ventilation, cardiac output, heart rate, stroke volume, increased concentrations of catecholamines in the blood, inner temperature, weight, height and human body surface area. The relative load is a criterion for the maximum workloads admissible for healthy and sick workers. Besides, the classification of effort can be more precise when based on the relative load than on the energy output. Based on our own and international empirical evidence and the laws of heat transfer and fluid mechanics, a model of temperature control system has been developed, involving the elements of human cardiovascular and respiratory systems. Using this model, we have been able to develop our own methods of determining the relative load, applying only the body core temperature (Tw) or heart rate within one minute (HR), body mass (m), height (H), and body surface area (AD) instead of VO,max. The values of the relative physical load (% VO2max) obtained by using our own methods do not differ significantly from those obtained by other methods and by other researchers. The developed methods for determining the relative physical load (% VO2max) do not require the exercise test to be performed, therefore, they may be considered (after verification in an experimental study) a feasible alternative to current methods.
Perry, E; Gulson, N; Liu Cross, T-W; Swanson, K S
2017-01-01
Working canines are deployed by the Federal Emergency Management Agency (FEMA), as part of a National Disaster Response Plan. Stress associated with helicopter flight and the resulting physical effects on the dog are unknown. Our objective was to test the hypotheses that (1) helicopter travel affects the physiology and faecal microbiota of working canines, but that (2) physiological consequences of helicopter travel will not negatively affect their work performance. A total of nine FEMA canines were loaded onto helicopters and flown for 30 min in July 2015. Rectal temperature, behavioural stress indicators and saliva swabs (for cortisol) were collected at baseline, loading, mid-flight and post-flight. After flight, canines completed a standardised search exercise to monitor work performance. Faecal samples were collected for microbial DNA extraction and Illumina sequencing. All canines were on a standardised diet (CANIDAE ® Grain Free PURE Land ® ) for 3 weeks prior to the study. Visible indicators of stress were observed at loading and at mid-flight and corresponded with an increase ( P < 0·05) in salivary cortisol from 5·4 µg/l (baseline) to 6·4 µg/l (loading). Additionally, rectal temperature increased ( P < 0·05) from 38·61°C (baseline) to 39·33°C (mid-flight) and 39·72°C (post-flight). Helicopter travel did not affect search performance ( P > 0·05). We found that α- and β-diversity measures of faecal microbiota were not affected ( P > 0·05). Our data suggest that although helicopter travel may cause physiological changes that have been associated with stress in working dogs, it does not make an impact on their search performance or the stability of faecal microbiota.
Eichler, Sarah; Salzwedel, Annett; Reibis, Rona; Nothroff, Jörg; Harnath, Axel; Schikora, Martin; Butter, Christian; Wegscheider, Karl; Völler, Heinz
2017-02-01
Background In the last decade, transcatheter aortic valve implantation has become a promising treatment modality for patients with aortic stenosis and a high surgical risk. Little is known about influencing factors of function and quality of life during multicomponent cardiac rehabilitation. Methods From October 2013 to July 2015, patients with elective transcatheter aortic valve implantation and a subsequent inpatient cardiac rehabilitation were enrolled in the prospective cohort multicentre study. Frailty-Index (including cognition, nutrition, autonomy and mobility), Short Form-12 (SF-12), six-minute walk distance (6MWD) and maximum work load in bicycle ergometry were performed at admission and discharge of cardiac rehabilitation. The relation between patient characteristics and improvements in 6MWD, maximum work load or SF-12 scales were studied univariately and multivariately using regression models. Results One hundred and thirty-six patients (80.6 ± 5.0 years, 47.8% male) were enrolled. 6MWD and maximum work load increased by 56.3 ± 65.3 m ( p < 0.001) and 8.0 ± 14.9 watts ( p < 0.001), respectively. An improvement in SF-12 (physical 2.5 ± 8.7, p = 0.001, mental 3.4 ± 10.2, p = 0.003) could be observed. In multivariate analysis, age and higher education were significantly associated with a reduced 6MWD, whereas cognition and obesity showed a positive predictive value. Higher cognition, nutrition and autonomy positively influenced the physical scale of SF-12. Additionally, the baseline values of SF-12 had an inverse impact on the change during cardiac rehabilitation. Conclusions Cardiac rehabilitation can improve functional capacity as well as quality of life and reduce frailty in patients after transcatheter aortic valve implantation. An individually tailored therapy with special consideration of cognition and nutrition is needed to maintain autonomy and empower octogenarians in coping with challenges of everyday life.
NASA Astrophysics Data System (ADS)
Hubacz, Frank, Jr.
The chemistry laboratory is an integral component of the learning experience for students enrolled in college-level general chemistry courses. Science education research has shown that guided inquiry investigations provide students with an optimum learning environment within the laboratory. These investigations reflect the basic tenets of constructivism by engaging students in a learning environment that allows them to experience what they learn and to then construct, in their own minds, a meaningful understanding of the ideas and concepts investigated. However, educational research also indicates that the physical plant of the laboratory environment combined with the procedural requirements of the investigation itself often produces a great demand upon a student's working memory. This demand, which is often superfluous to the chemical concept under investigation, creates a sensory overload or extraneous cognitive load within the working memory and becomes a significant obstacle to student learning. Extraneous cognitive load inhibits necessary schema formation within the learner's working memory thereby impeding the transfer of ideas to the learner's long-term memory. Cognitive Load Theory suggests that instructional material developed to reduce extraneous cognitive load leads to an improved learning environment for the student which better allows for schema formation. This study first compared the cognitive load demand, as measured by mental effort, experienced by 33 participants enrolled in a first-year general chemistry course in which the treatment group, using technology based investigations, and the non-treatment group, using traditional labware, investigated identical chemical concepts on five different exercises. Mental effort was measured via a mental effort survey, a statistical comparison of individual survey results to a procedural step count, and an analysis of fourteen post-treatment interviews. Next, a statistical analysis of achievement was completed by comparing lab grade averages, final exam averages, and final course grade averages between the two groups. Participant mental effort survey results showed significant positive effects of technology in reducing cognitive load for two laboratory investigations. One investigation revealed a significant difference in achievement measured by lab grade average comparisons. Although results of this study are inconclusive as to the usefulness of technology-driven investigations to affect learning, recommendations for further study are discussed.
NASA Astrophysics Data System (ADS)
Liu, Changyi; Zhao, Hongwei; Ma, Zhichao; Qiao, Yuansen; Hong, Kun; Ren, Zhuang; Zhang, Jianhai; Pei, Yongmao; Ren, Luquan
2018-02-01
Functional materials represented by ferromagnetics and ferroelectrics are widely used in advanced sensor and precision actuation due to their special characterization under coupling interactions of complex loads and external physical fields. However, the conventional devices for material characterization can only provide a limited type of loads and physical fields and cannot simulate the actual service conditions of materials. A multi-field coupling instrument for characterization has been designed and implemented to overcome this barrier and measure the comprehensive physical properties under complex service conditions. The testing forms include tension, compression, bending, torsion, and fatigue in mechanical loads, as well as different external physical fields, including electric, magnetic, and thermal fields. In order to offer a variety of information to reveal mechanical damage or deformation forms, a series of measurement methods at the microscale are integrated with the instrument including an indentation unit and in situ microimaging module. Finally, several coupling experiments which cover all the loading and measurement functions of the instrument have been implemented. The results illustrate the functions and characteristics of the instrument and then reveal the variety in mechanical and electromagnetic properties of the piezoelectric transducer ceramic, TbDyFe alloy, and carbon fiber reinforced polymer under coupling conditions.
2012-01-12
fabrication of the composite indicate physical deformities and defects, including entanglement of carbon nanotubes and fused contacts, that are understood...working distance, and spot size, 2.5) of MWCNT array batch of which the composite was made and tested: (a) Entanglements of Individual Nanotubes...electron, photon and phonon) in these materials is critical to their reliable and robust performance, thus accommodating denser circuits 2 and higher
Data-Driven Residential Load Modeling and Validation in GridLAB-D
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gotseff, Peter; Lundstrom, Blake
Accurately characterizing the impacts of high penetrations of distributed energy resources (DER) on the electric distribution system has driven modeling methods from traditional static snap shots, often representing a critical point in time (e.g., summer peak load), to quasi-static time series (QSTS) simulations capturing all the effects of variable DER, associated controls and hence, impacts on the distribution system over a given time period. Unfortunately, the high time resolution DER source and load data required for model inputs is often scarce or non-existent. This paper presents work performed within the GridLAB-D model environment to synthesize, calibrate, and validate 1-second residentialmore » load models based on measured transformer loads and physics-based models suitable for QSTS electric distribution system modeling. The modeling and validation approach taken was to create a typical GridLAB-D model home that, when replicated to represent multiple diverse houses on a single transformer, creates a statistically similar load to a measured load for a given weather input. The model homes are constructed to represent the range of actual homes on an instrumented transformer: square footage, thermal integrity, heating and cooling system definition as well as realistic occupancy schedules. House model calibration and validation was performed using the distribution transformer load data and corresponding weather. The modeled loads were found to be similar to the measured loads for four evaluation metrics: 1) daily average energy, 2) daily average and standard deviation of power, 3) power spectral density, and 4) load shape.« less
Concurrent Working Memory Load Can Facilitate Selective Attention: Evidence for Specialized Load
ERIC Educational Resources Information Center
Park, Soojin; Kim, Min-Shik; Chun, Marvin M.
2007-01-01
Load theory predicts that concurrent working memory load impairs selective attention and increases distractor interference (N. Lavie, A. Hirst, J. W. de Fockert, & E. Viding, see record 2004-17825-003). Here, the authors present new evidence that the type of concurrent working memory load determines whether load impairs selective attention or not.…
Role of differential physical properties in the collective mechanics and dynamics of tissues
NASA Astrophysics Data System (ADS)
Das, Moumita
Living cells and tissues are highly mechanically sensitive and active. Mechanical stimuli influence the shape, motility, and functions of cells, modulate the behavior of tissues, and play a key role in several diseases. In this talk I will discuss how collective biophysical properties of tissues emerge from the interplay between differential mechanical properties and statistical physics of underlying components, focusing on two complementary tissue types whose properties are primarily determined by (1) the extracellular matrix (ECM), and (2) individual and collective cell properties. I will start with the structure-mechanics-function relationships in articular cartilage (AC), a soft tissue that has very few cells, and its mechanical response is primarily due to its ECM. AC is a remarkable tissue: it can support loads exceeding ten times our body weight and bear 60+ years of daily mechanical loading despite having minimal regenerative capacity. I will discuss the biophysical principles underlying this exceptional mechanical response using the framework of rigidity percolation theory, and compare our predictions with experiments done by our collaborators. Next I will discuss ongoing theoretical work on how the differences in cell mechanics, motility, adhesion, and proliferation in a co-culture of breast cancer cells and healthy breast epithelial cells may modulate experimentally observed differential migration and segregation. Our results may provide insights into the mechanobiology of tissues with cell populations with different physical properties present together such as during the formation of embryos or the initiation of tumors. This work was partially supported by a Cottrell College Science Award.
Hemostatic kaolin-polyurethane foam composites for multifunctional wound dressing applications.
Lundin, Jeffrey G; McGann, Christopher L; Daniels, Grant C; Streifel, Benjamin C; Wynne, James H
2017-10-01
There are numerous challenges associated with the acute care of traumatic limb injuries in forward military settings. A lack of immediate medical facilities necessitates that the wound dressing perform multiple tasks including exudate control, infection prevention, and physical protection of the wound for extended periods of time. Here, kaolin was incorporated into recently developed robust polyurethane (PU) hydrogel foams at 1-10wt% in an effort to impart hemostatic character. ATR-IR and gel fraction analysis demonstrated that the facile, one-pot synthesis of the PU hydrogel was unaffected by kaolin loading, as well as the use of a non-toxic catalyst, which significantly improved cytocompatibility of the materials. Kaolin was generally well dispersed throughout the PU matrix, though higher loadings exhibited minor evidence of aggregation. Kaolin-PU composites exhibited burst release of ciprofloxacin over 2h, the initial release rates of which increased with kaolin loading. Kaolin loading imparted excellent hemostatic character to the PU foams at relatively low loading levels (5wt%). This work demonstrates the simple and inexpensive synthesis of robust, hemostatic, and absorptive kaolin-PU foams that have promising potential as multifunctional wound dressing materials. Published by Elsevier B.V.
Prokopenko, L V; Afanas'eva, R F; Bessonova, N A; Burmistrova, O V; Losik, T K; Konstantinov, E I
2013-01-01
Studies of heat state of human involved into physical work in heating environment and having various protective clothing on demonstrated value of the protective clothing in modifying thermal load on the body and possible decrease of this load through air temperature and humidity correction, shorter stay at workplace. The authors presented hygienic requirements to air temperatures range in accordance with allowable body heating degree, suggested mathematic model to forecast integral parameter of human functional state in accordance with type of protective clothing applied. The article also covers necessity of upper air temperature limit during hot season, for applying protective clothing made of materials with low air permeability and hydraulic conductivity.
Glass, Stephen M; Ross, Scott E
2015-10-01
Failure to meet minimum performance standards is a leading cause of attrition from basic combat training. A standardized assessment such as the Functional Movement Screen™ (FMS™) could help identify movement behaviors relevant to physical performance in tactical occupations. Previous work has demonstrated only marginal association between FMS™ tests and performance outcomes, but adding a load challenge to this movement assessment may help highlight performance-limiting behaviors. The purposes of this investigation were to quantify the effect of load on FMS™ tests and determine the extent to which performance outcomes could be predicted using scores from both loaded and unloaded FMS™ conditions. Crossover Trial. Thirteen female and six male recreationally active college students (21 ± 1.37 years, 168 ± 9.8 cm, 66 ± 12.25 kg) completed the FMS™ under (1) a control condition (FMS™C), and (2) an 18.10kg weight vest condition (FMS™W). Balance was assessed using a force plate in double-legged stance and tactical physical performance was evaluated via completion times in a battery of field tests. For each condition, penalized regression was used to select models from the seven FMS™ component tests to predict balance and performance outcomes. Data were collected during a single session lasting approximately three hours per participant. For balance, significant predictors were identified from both conditions but primarily predicted poorer balance with increasing FMS™ scores. For tactical performance, models were retained almost exclusively from FMS™W and generally predicted better performance with higher item scores. The current results suggest that FMS™ screening with an external load could help predict performance relevant to tactical occupations. Sports medicine and fitness professionals interested in performance outcomes may consider assessing movement behaviors under a load. 3.
Supplemental Reactor Physics Calculations and Analysis of ELF Mk 1A Fuel
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pope, Michael A.
2014-10-01
These calculations supplement previous the reactor physics work evaluating the Enhanced Low Enriched Uranium (LEU) Fuel (ELF) Mk 1A element. This includes various additional comparisons between the current Highly Enriched Uranium (HEU) and LEU along with further characterization of the performance of the ELF fuel. The excess reactivity to be held down at BOC for ELF Mk 1A fuel is estimated to be approximately $2.75 greater than with HEU for a typical cycle. This is a combined effect of the absence of burnable poison in the ELF fuel and the reduced neck shim worth in LEU fuel compared to HEU.more » Burnable poison rods were conceptualized for use in the small B positions containing Gd2O3 absorber. These were shown to provide $2.37 of negative reactivity at BOC and to burn out in less than half of a cycle. The worth of OSCCs is approximately the same between HEU and ELF Mk 1A (LEU) fuels in the representative loading evaluated. This was evaluated by rotating all banks simultaneously. The safety rod worth is relatively unchanged between HEU and ELF Mk 1A (LEU) fuels in the representative loading evaluated. However, this should be reevaluated with different loadings. Neutron flux, both total and fast (>1 MeV), is either the same or reduced upon changing from HEU to ELF Mk 1A (LEU) fuels in the representative loading evaluated. This is consistent with the well-established trend of lower neutron fluxes for a given power in LEU than HEU.The IPT loop void reactivity is approximately the same or less positive with ELF Mk 1A (LEU) fuel than HEU in the representative loading evaluated.« less
14. BUILDING NO. 445, PHYSICS LAB (FORMERLY GUN BAG LOADING), ...
14. BUILDING NO. 445, PHYSICS LAB (FORMERLY GUN BAG LOADING), LOOKING EAST AT SOUTHWEST END OF BUILDING. HVAC EQUIPMENT LOCATED OUTDOORS IN FOREGROUND. DUCTS CONDUCT HOT OR COLD AIR INDOORS. ROUND PIPES ARE INSULATED STEAM LINES. BUILDING NO. 448, ORDNANCE FACILITY, IN BACKGROUND. - Picatinny Arsenal, 400 Area, Gun Bag Loading District, State Route 15 near I-80, Dover, Morris County, NJ
Opposite effects of capacity load and resolution load on distractor processing.
Zhang, Weiwei; Luck, Steven J
2015-02-01
According to the load theory of attention, an increased perceptual load reduces distractor processing whereas an increased working memory load facilitates distractor processing. Here we raise the possibility that the critical distinction may instead be between an emphasis on resolution and an emphasis on capacity. That is, perceptual load manipulations typically emphasize resolution (fine-grained discriminations), whereas working memory load manipulations typically emphasize capacity (simultaneous processing of multiple relevant stimuli). To test the plausibility of this hypothesis, we used a visual working memory task that emphasized either the number of items to be stored (capacity load, retaining 2 vs. 4 colors) or the precision of the representations (resolution load, detecting small vs. large color changes). We found that an increased capacity load led to increased flanker interference (a measure of distractor processing), whereas an increased resolution load led to reduced flanker interference. These opposite effects of capacity load and resolution load on distractor processing mirror the previously described opposite effects of perceptual load and working memory load.
Opposite Effects of Capacity Load and Resolution Load on Distractor Processing
Zhang, Weiwei; Luck, Steven J.
2014-01-01
According to the load theory of attention, an increased perceptual load reduces distractor processing whereas an increased working memory load facilitates distractor processing. Here we raise the possibility that the critical distinction may instead be between an emphasis on resolution and an emphasis on capacity. That is, perceptual load manipulations typically emphasize resolution (fine-grained discriminations), whereas working memory load manipulations typically emphasize capacity (simultaneous processing of multiple relevant stimuli). To test the plausibility of this hypothesis, we used a visual working memory task that emphasized either the number of items to be stored (capacity load, retaining two versus four colors) or the precision of the representations (resolution load, detecting small versus large color changes). We found that an increased capacity load led to increased flanker interference (a measure of distractor processing), whereas an increased resolution load led to reduced flanker interference. These opposite effects of capacity load and resolution load on distractor processing mirror the previously described opposite effects of perceptual load and working memory load. PMID:25365573
7 CFR 1710.209 - Approval requirements for load forecast work plans.
Code of Federal Regulations, 2010 CFR
2010-01-01
... cooperate in the preparation of and submittal of the load forecast work plan of their power supply borrower. (b) An approved load forecast work plan establishes the process for the preparation and maintenance... approved load forecast work plan must outline the coordination and preparation requirements for both the...
Wilson, W.M.; Dufour, D.L.; Staten, L.K.; Barac-Nieto, M.; Reina, J.C.; Spurr, G.B.
1999-11-01
This article tests the hypothesis that the presence of gastrointestinal parasites in Colombian boys is negatively associated with anthropometric characteristics, physical work capacity, blood hemoglobin (Hb) levels, and nutritional status. Anthropometric, Hb, &Vdot;O(2) max, and parasite load data were collected on 1,016 boys in Cali, Colombia. The boys were classified as lower socioeconomic class (SEC) from either urban or rural environments, and upper SEC from an urban environment. Sixty-three percent of the boys were infected with gastrointestinal parasites and, of the infected boys, 80-95% had light parasite loads. Parasites found included Necator americanus, Ascaris lumbricoides, Entamoeba histolytica, Trichuris trichiura, Giardia spp., and Enterobius vermicularis. Infected boys had significantly lower weight, stature, weight-for-height (among 6-9-year-old boys), Hb levels, and &Vdot;O(2) max (ANCOVA, controlling for age and SEC). In terms of nutritional status, infected boys were 1.47 times more likely to be classified as iron deficient than noninfected boys (chi-square, P < 0.001), and 1.61 times more likely to be classified as stunted (P < 0.001). Infection was not associated with wasting in any SEC group. In conclusion, light to moderate gastrointestinal parasite loads were associated with significantly lower weight, stature, weight-for-height (in 6-9-year-old boys), Hb levels, and &Vdot;O(2) max, and a significantly higher frequency of IDA and stunting. These data suggest that comprehensive analyses of the nutritional status of populations in regions endemic for parasitic infection should include testing for the presence of infection. Am. J. Hum. Biol. 11:763-771, 1999. Copyright 1999 Wiley-Liss, Inc.
Suarez-Arrones, L; Torreño, N; Requena, B; Sáez De Villarreal, E; Casamichana, D; Barbero-Alvarez, J C; Munguía-Izquierdo, D
2015-12-01
The aim was to quantify for the first time the physical and physiological profile of professional soccer players in official games using GPS and heart rate (HR) response. Thirty professional soccer players were investigated during a half in competitive club level matches (N.=348) using GPS devices. The relative total distance was 118.9±10.7 m∙min(-1) and player's Work-To-Rest Ratio was 2.1:1. Defenders covered the lowest total distance, while Second-Strikers (2(nd)S) and Wide-Midfielders (W-MD) traveled the greatest total distance. Defenders presented the lowest Work-To-Rest Ratio values. Playing position also impacted on all sprinting performance results, except in average sprint distance and time of sprint. The number of sprints and repeated-sprint sequences recorded by the W-MD and Strikers (S) were significantly greater than any other group. The average HR recorded was 87.1%HRmax and the relationship between the external and internal load value (Effindex) was 1.4 with significant differences in both between playing positions. W-MD recorded a significantly smaller average HR than any other group and Centre-Backs showed a significantly smaller Effindex value than any other group. Conversely, W-MD showed a significantly greater Effindex value than any other group, except the 2(nd)S. This study has verified a number of statistically significant differences between the different playing positions. Coaches should be focused on the specific physical and physiological requirements of the playing positions to optimize the training prescription in soccer. The relationships between external and internal load measures among position-specific indicates that players with less overall running performance during match-play were the worst in Effindex.
NASA Technical Reports Server (NTRS)
Vasilyeva, V. V.; Korableva, Y. N.; Trunin, V. V.
1980-01-01
A program of exercises was developed and tested, consisting of a 12 minute session on a variable load bicycle ergometer and a 10-11 min. run with brief stretching and resting sessions between. Physical performance capacity was measured before, during, and after the period of the experiment and physical exams conducted. After a 4 month test period involving 30 men, aged 25-35, the program was found to be successful in increasing physical performance capacity. The PWC170 increased an average of 22 percent and maximum oxygen consumption 14 percent. Arterial pressure dropped (120/75 to 114/68), vital capacity of lungs increased by 6 percent, strength of respiratory muscles by 8.8 percent, duration of respiratory delay by 18 percent. Duration of cardiac cycles increased, stress index decreased. Cardiac contraction rate 2 minutes after work on the ergometer decreased from 118 to 102 bt/min.
Continuum modeling of neuronal cell under blast loading
Jérusalem, Antoine; Dao, Ming
2012-01-01
Traumatic brain injuries have recently been put under the spotlight as one of the most important causes of accidental brain dysfunctions. Significant experimental and modeling efforts are thus ongoing to study the associated biological, mechanical and physical mechanisms. In the field of cell mechanics, progresses are also being made at the experimental and modeling levels to better characterize many of the cell functions such as differentiation, growth, migration and death, among others. The work presented here aims at bridging both efforts by proposing a continuum model of neuronal cell submitted to blast loading. In this approach, cytoplasm, nucleus and membrane (plus cortex) are differentiated in a representative cell geometry, and different material constitutive models are adequately chosen for each one. The material parameters are calibrated against published experimental work of cell nanoindentation at multiple rates. The final cell model is ultimately subjected to blast loading within a complete fluid-structure interaction computational framework. The results are compared to the nanoindentation simulation and the specific effects of the blast wave on the pressure and shear levels at the interfaces are identified. As a conclusion, the presented model successfully captures some of the intrinsic intracellular phenomena occurring during its deformation under blast loading and potentially leading to cell damage. It suggests more particularly the localization of damage at the nucleus membrane similarly to what has already been observed at the overall cell membrane. This degree of damage is additionally predicted to be worsened by a longer blast positive phase duration. As a conclusion, the proposed model ultimately provides a new three dimensional computational tool to evaluate intracellular damage during blast loading. PMID:22562014
A high-speed, eight-wavelength visible light-infrared pyrometer for shock physics experiments
NASA Astrophysics Data System (ADS)
Wang, Rongbo; Li, Shengfu; Zhou, Weijun; Luo, Zhen-Xiong; Meng, Jianhua; Tian, Jianhua; He, Lihua; Cheng, Xianchao
2017-09-01
An eight-channel, high speed pyrometer for precise temperature measurement is designed and realized in this work. The addition of longer-wavelength channels sensitive at lower temperatures highly expands the measured temperature range, which covers the temperature of interest in shock physics from 1500K-10000K. The working wavelength range is 400-1700nm from visible light to near-infrared (NIR). Semiconductor detectors of Si and InGaAs are used as photoelectric devices, whose bandwidths are 50MHz and 150MHz respectively. Benefitting from the high responsivity and high speed of detectors, the time resolution of the pyrometer can be smaller than 10ns. By combining the high-transmittance beam-splitters and narrow-bandwidth filters, the peak spectrum transmissivity of each channel can be higher than 60%. The gray-body temperatures of NaI crystal under shock-loading are successfully measured by this pyrometer.
Posturedontics: How does dentistry fit you?
Jodalli, Praveen S; Kurana, Suchi; Shameema; Ragher, Mallikarjuna; Khed, Jaishree; Prabhu, Vishnu
2015-08-01
Dentists are at high risk for musculoskeletal disorders (MSD's) due to their work. MSD's is an umbrella term for number of injuries affecting different parts of the body, including joints, muscles, tendons, nerves that can arise from sudden exertion or making the same motions repeatedly. These injuries can develop over time and can lead to long-term disability. Dental professional often develop musculoskeletal problems due to bad working habits, uncomfortable physical posture causing unnecessary musculoskeletal loading, discomfort and fatigue. Ergonomic principles when it is applied, it will help to reduce stress and eliminate many potential injuries and disorders associated with the overuse of muscles, bad posture, and repeated tasks. This can be accomplished by using a proper dental chair, lighting and the selection of ergonomically-friendly equipment to fit the dental professionals physical capabilities and limitations. This review addresses about the basics of ergonomics, positioning, viewing, handling, and prevention of MSD's.
Posturedontics: How does dentistry fit you?
Jodalli, Praveen S.; Kurana, Suchi; Shameema; Ragher, Mallikarjuna; Khed, Jaishree; Prabhu, Vishnu
2015-01-01
Dentists are at high risk for musculoskeletal disorders (MSD's) due to their work. MSD's is an umbrella term for number of injuries affecting different parts of the body, including joints, muscles, tendons, nerves that can arise from sudden exertion or making the same motions repeatedly. These injuries can develop over time and can lead to long-term disability. Dental professional often develop musculoskeletal problems due to bad working habits, uncomfortable physical posture causing unnecessary musculoskeletal loading, discomfort and fatigue. Ergonomic principles when it is applied, it will help to reduce stress and eliminate many potential injuries and disorders associated with the overuse of muscles, bad posture, and repeated tasks. This can be accomplished by using a proper dental chair, lighting and the selection of ergonomically-friendly equipment to fit the dental professionals physical capabilities and limitations. This review addresses about the basics of ergonomics, positioning, viewing, handling, and prevention of MSD's. PMID:26538885
Work-related musculoskeletal disorders among physical therapists: A comprehensive narrative review.
Milhem, Mohammad; Kalichman, Leonid; Ezra, David; Alperovitch-Najenson, Deborah
2016-01-01
Healthcare workers, especially those with direct patient contact are amongst professions with the highest rate of workrelated musculoskeletal disorders (WMSDs), physical therapists (PTs) being one of them. Our objective was to review current knowledge relating to the prevalence, risk factors and prevention of WMSDs among PTs. Pubmed, Google Scholar and PEDro databases were searched for terms relating to WMSDs in PTs from inception to 2015. The prevalence of WMSDs among PTs was high, with lifetime prevalence reported as 55-91%, and 12-month prevalence ranges 40-91.3%, and the lower back as the most frequently affected, with estimates of a lifetime prevalence ranging 26-79.6%, and a 12-month prevalence ranging 22-73.1%, followed most often by the neck, upper back and shoulders. The major risk factors for workrelated low back pain (LBP) were: lifting, transferring, repetitive movements, awkward and static postures, physical load, treating a large number of patients in a single day and working while injured. Low back pain seems to be age- and genderrelated with a higher prevalence in females, younger PTs and PTs working in rehabilitation settings. Physical therapists, as a consequence of work-related LBP, may seek treatment, modify their daily living and leisure (lifestyle) activities, use aids and equipment or change their specialty area either within the profession or by leaving it. Skills and knowledge as to correct body mechanics do not prevent work-related injuries. Mechanical aids used for a patient transfer should be adopted by PTs and new strategies should be developed to reduce their WMSDs without compromising the quality of treatment. Int J Occup Med Environ Health 2016;29(5):735-747. This work is available in Open Access model and licensed under a CC BY-NC 3.0 PL license.
Morphological effects on sensitivity of heterogeneous energetic materials
NASA Astrophysics Data System (ADS)
Roy, Sidhartha; Rai, Nirmal; Sen, Oishik; Udaykumar, H. S.
2017-06-01
The mesoscale physical response under shock loading in heterogeneous energetics is inherently linked to the microstructural characteristics. The current work demonstrates the connection between the microstructural features of porous energetic material and its sensitivity. A unified levelset based framework is developed to characterize the microstructures of a given sample. Several morphological metrics describing the mesoscale geometry of the materials are extracted using the current tool including anisotropy, tortuosity, surface to volume, nearest neighbors, size and curvature distributions. The relevant metrics among the ones extracted are identified and correlated to the mesoscale response of the energetic materials under shock loading. Two classes of problems are considered here: (a) field of idealized voids embedded in the HMX material and (b) real samples of pressed HMX. The effects of stochasticity associated with void arrangements on the sensitivity of the energetic material samples are shown. In summary, this work demonstrates the relationship between the mesoscale morphology and shock response of heterogeneous energetic materials using a levelset based framework.
Transient loads identification for a standoff metallic thermal protection system panel.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hundhausen, R. J.; Adams, Douglas E.; Derriso, Mark
2004-01-01
Standoff thermal protection system (TPS) panels are critical structural components in future aerospace vehicles because they protect the vehicle from the hostile environment encountered during space launch and reentry. Consequently, the panels are exposed to a variety of loads including high temperature thermal stresses, thermal shock, acoustic pressure, and foreign object impacts. Transient impacts are especially detrimental because they can cause immediate and severe degradation of the panel in the form of, for example, debonding and buckling of the face sheet, cracking of the fasteners, or deformation of the standoffs. Loads identification methods for determining the magnitude and location ofmore » impact loads provide an indication of TPS components that may be more susceptible to failure. Furthermore, a historical database of impact loads encountered can be retained for use in the development of statistical models that relate impact loading to panel life. In this work, simulated inservice transient loads are identified experimentally using two methods: a physics-based approach and an inverse Frequency Response Function (FRF) approach. It is shown that by applying the inverse FRF method, the location and magnitude of these simulated impacts can be identified with a high degree of accuracy. The identified force levels vary significantly with impact location due to the differences in panel deformation at the impact site indicating that resultant damage due to impacts would vary with location as well.« less
Computer Based Collaborative Problem Solving for Introductory Courses in Physics
NASA Astrophysics Data System (ADS)
Ilie, Carolina; Lee, Kevin
2010-03-01
We discuss collaborative problem solving computer-based recitation style. The course is designed by Lee [1], and the idea was proposed before by Christian, Belloni and Titus [2,3]. The students find the problems on a web-page containing simulations (physlets) and they write the solutions on an accompanying worksheet after discussing it with a classmate. Physlets have the advantage of being much more like real-world problems than textbook problems. We also compare two protocols for web-based instruction using simulations in an introductory physics class [1]. The inquiry protocol allowed students to control input parameters while the worked example protocol did not. We will discuss which of the two methods is more efficient in relation to Scientific Discovery Learning and Cognitive Load Theory. 1. Lee, Kevin M., Nicoll, Gayle and Brooks, Dave W. (2004). ``A Comparison of Inquiry and Worked Example Web-Based Instruction Using Physlets'', Journal of Science Education and Technology 13, No. 1: 81-88. 2. Christian, W., and Belloni, M. (2001). Physlets: Teaching Physics With Interactive Curricular Material, Prentice Hall, Englewood Cliffs, NJ. 3. Christian,W., and Titus,A. (1998). ``Developing web-based curricula using Java Physlets.'' Computers in Physics 12: 227--232.
Water and coffee: a systems approach to improving coffee harvesting work in Nicaragua.
Silverstein, Barbara A; Bao, Stephen S; Russell, Steven; Stewart, Kate
2012-12-01
The aim of this study was to reduce the physical load on coffee-harvesting workers while maintaining productivity. Coffee is second to oil in commodity trading. Water is becoming scarce worldwide. The global virtual water footprint for one cup of coffee is 140 liters. Shade-grown coffee is one approach to reducing the water footprint. A participatory ergonomics approach was used during two Nicaraguan shade-grown coffee harvesting seasons to reduce the physical load on harvesters with the use of a newly designed bag instead of a basket strapped around the waist. Productivity in the mountainous, shade-grown coffee farms was maintained while physical load on the worker was improved somewhat.Among basket users, 84.2% reported pain in at least one body area compared with 78.9% of bag users (ns). Nonetheless, 74% of participants liked the bag "much better" than the basket. Workers identified ways the bag could be improved further with the use of local materials.These suggestions included (a) reducing the horizontal distance of the bag to reduce reach and (b) having waterproof material on the bag between the worker and the bag to reduce moisture and damage to the berries.There was no difference in productivity between using the bag and using the small basket. Workers are extending this participatory approach to how to get the harvested coffee cherries down the mountain other than carrying 40-kg bags on their backs. The ultimate goal is to make the coffee-harvesting bag design available to harvesters around the world.
Schapschröer, M; Baker, J; Schorer, J
2016-08-01
In the context of perceptual-cognitive expertise it is important to know whether physiological loads influence perceptual-cognitive performance. This study examined whether a handball specific physical exercise load influenced participants' speed and accuracy in a flicker task. At rest and during a specific interval exercise of 86.5-90% HRmax, 35 participants (experts: n=8, advanced: n=13, novices, n=14) performed a handball specific flicker task with two types of patterns (structured and unstructured). For reaction time, results revealed moderate effect sizes for group, with experts reacting faster than advanced and advanced reacting faster than novices, and for structure, with structured videos being performed faster than unstructured ones. A significant interaction for structure×group was also found, with experts and advanced players faster for structured videos, and novices faster for unstructured videos. For accuracy, significant main effects were found for structure with structured videos solved more accurately. A significant interaction for structure×group was revealed, with experts and advanced more accurate for structured scenes and novices more accurate for unstructured scenes. A significant interaction was also found for condition×structure; at rest, unstructured and structured scenes were performed with the same accuracy while under physical exercise, structured scenes were solved more accurately. No other interactions were found. These results were somewhat surprising given previous work in this area, although the impact of a specific physical exercise on a specific perceptual-cognitive task may be different from those tested generally. Copyright © 2016 Elsevier B.V. All rights reserved.
Effect of Physical Load on Aerobic Exercise Performance during Heat Stress.
Kenefick, Robert W; Heavens, Kristen R; Luippold, Adam J; Charkoudian, Nisha; Schwartz, Steven A; Cheuvront, Samuel N
2017-12-01
This study aimed to investigate the effect of increasing external loads on 5-km treadmill time trial (TT) performance in 20°C and 40°C environmental conditions and to construct an ecologically relevant performance prediction decision aid. Twenty-six male and four female volunteers (age, 23.5 ± 6.9 yr; weight, 76.0 ± 8.9 kg; height, 1.75 ± 0.07 m; V˙O2peak, 50.7 ± 4.5 mL·kg·min) participated in a counterbalanced, mixed-model design, with each subject assigned to a load group (20%, 30%, or 50% body mass (BM); n = 10 per group). Volunteers performed three, self-paced 5-km familiarization TT (treadmill) without external load. Each volunteer then performed a 5-km TT in each environment with loads of either 20% (n = 10), 30% (n = 10), or 50% (n = 10) of BM. 1) Loads of (20%, 30%, and 50% of BM) impaired 5-km TT performance compared with that when unloaded (P < 0.05); 2) the time penalties of the 20% and 30% load were <50% load (P < 0.05); 3) in all trials, the addition of heat exposure reduced 5-km TT performance beyond the penalty of load itself (P < 0.05); and 4) the combination of heat and 50% load resulted in a substantial penalty such that continuous work was not sustainable for all of the volunteers. Relative to prediction models using fixed or constant workload exercise trials, an ecologically valid decision aid was developed from self-paced data, in which pace (km·h) can be predicted for individual levels of heat, load, or heat + load in combination.
Physical and JIT Model Based Hybrid Modeling Approach for Building Thermal Load Prediction
NASA Astrophysics Data System (ADS)
Iino, Yutaka; Murai, Masahiko; Murayama, Dai; Motoyama, Ichiro
Energy conservation in building fields is one of the key issues in environmental point of view as well as that of industrial, transportation and residential fields. The half of the total energy consumption in a building is occupied by HVAC (Heating, Ventilating and Air Conditioning) systems. In order to realize energy conservation of HVAC system, a thermal load prediction model for building is required. This paper propose a hybrid modeling approach with physical and Just-in-Time (JIT) model for building thermal load prediction. The proposed method has features and benefits such as, (1) it is applicable to the case in which past operation data for load prediction model learning is poor, (2) it has a self checking function, which always supervises if the data driven load prediction and the physical based one are consistent or not, so it can find if something is wrong in load prediction procedure, (3) it has ability to adjust load prediction in real-time against sudden change of model parameters and environmental conditions. The proposed method is evaluated with real operation data of an existing building, and the improvement of load prediction performance is illustrated.
Koshino, Hideya
2017-01-01
Working memory and attention are closely related. Recent research has shown that working memory can be viewed as internally directed attention. Working memory can affect attention in at least two ways. One is the effect of working memory load on attention, and the other is the effect of working memory contents on attention. In the present study, an interaction between working memory contents and perceptual load in distractor processing was investigated. Participants performed a perceptual load task in a standard form in one condition (Single task). In the other condition, a response-related distractor was maintained in working memory, rather than presented in the same stimulus display as a target (Dual task). For the Dual task condition, a significant compatibility effect was found under high perceptual load; however, there was no compatibility effect under low perceptual load. These results suggest that the way the contents of working memory affect visual search depends on perceptual load. Copyright © 2016 Elsevier B.V. All rights reserved.
ERIC Educational Resources Information Center
Jamniczky, Heather A.; McLaughlin, Kevin; Kaminska, Malgorzata E.; Raman, Maitreyi; Somayaji, Ranjani; Wright, Bruce; Ma, Irene W. Y.
2015-01-01
Ultrasonography is increasingly used for teaching anatomy and physical examination skills but its effect on cognitive load is unknown. This study aimed to determine ultrasound's perceived utility for learning, and to investigate the effect of cognitive load on its perceived utility. Consenting first-year medical students (n?=?137) completed…
A new physical performance classification system for elite handball players: cluster analysis
Chirosa, Ignacio J.; Robinson, Joseph E.; van der Tillaar, Roland; Chirosa, Luis J.; Martín, Isidoro Martínez
2016-01-01
Abstract The aim of the present study was to identify different cluster groups of handball players according to their physical performance level assessed in a series of physical assessments, which could then be used to design a training program based on individual strengths and weaknesses, and to determine which of these variables best identified elite performance in a group of under-19 [U19] national level handball players. Players of the U19 National Handball team (n=16) performed a set of tests to determine: 10 m (ST10) and 20 m (ST20) sprint time, ball release velocity (BRv), countermovement jump (CMJ) height and squat jump (SJ) height. All players also performed an incremental-load bench press test to determine the 1 repetition maximum (1RMest), the load corresponding to maximum mean power (LoadMP), the mean propulsive phase power at LoadMP (PMPPMP) and the peak power at LoadMP (PPEAKMP). Cluster analyses of the test results generated four groupings of players. The variables best able to discriminate physical performance were BRv, ST20, 1RMest, PPEAKMP and PMPPMP. These variables could help coaches identify talent or monitor the physical performance of athletes in their team. Each cluster of players has a particular weakness related to physical performance and therefore, the cluster results can be applied to a specific training programmed based on individual needs. PMID:28149376
Bennett, Ilana J.; Rivera, Hannah G.; Rypma, Bart
2013-01-01
Previous studies examining age-group differences in working memory load-related neural activity have yielded mixed results. When present, age-group differences in working memory capacity are frequently proposed to underlie these neural effects. However, direct relationships between working memory capacity and working memory load-related activity have only been observed in younger adults. These relationships remain untested in healthy aging. Therefore, the present study examined patterns of working memory load-related activity in 22 younger and 20 older adults and assessed the contribution of working memory capacity to these load-related effects. Participants performed a partial-trial delayed response item recognition task during functional magnetic resonance imaging. In this task, participants encoded either 2 or 6 letters, maintained them during a delay, and then indicated whether a probe was present in the memory set. Behavioral results revealed faster and more accurate responses to load 2 versus 6, with age-group differences in this load condition effect for the accuracy measure. Neuroimaging results revealed one region (medial superior frontal gyrus) that showed age-group differences in load-related activity during the retrieval period, with less (greater) neural activity for the low versus high load condition in younger (older) adults. Furthermore, for older adults, load-related activity did not vary as a function of working memory capacity. Thus, working memory-related activity varies with healthy aging, but these patterns are not due solely to working memory capacity. Neurocognitive aging theories that feature capacity will need to account for these results. PMID:23357076
Physical Properties of an Ag-Doped Bioactive Flowable Composite Resin
Kattan, Hiba; Chatzistavrou, Xanthippi; Boynton, James; Dennison, Joseph; Yaman, Peter; Papagerakis, Petros
2015-01-01
The aim of this work was to study the physical and antibacterial properties of a flowable resin composite incorporating a sol-gel derived silver doped bioactive glass (Ag-BGCOMP). The depth of the cure was calculated by measuring the surface micro-hardness for the top and bottom surfaces. The volumetric polymerization shrinkage was measured by recording the linear shrinkage as change in length, while the biaxial flexural strength was studied measuring the load at failure. The antibacterial properties of the samples were tested against Streptococcus mutans (S. mutans) and Lactobacillus casei (L. casei). The measured values were slightly decreased for all tested physical properties compared to those of control group (flowable resin composite without Ag-BG), however enhanced bacteria inhibition was observed for Ag-BGCOMP. Ag-BGCOMP could find an application in low stress-bearing areas as well as in small cavity preparations to decrease secondary caries. This work provides a good foundation for future studies on evaluating the effects of Ag-BG addition into packable composites for applications in larger cavity preparations where enhanced mechanical properties are needed. PMID:28793463
Muscle activity pattern dependent pain development and alleviation.
Sjøgaard, Gisela; Søgaard, Karen
2014-12-01
Muscle activity is for decades considered to provide health benefits irrespectively of the muscle activity pattern performed and whether it is during e.g. sports, transportation, or occupational work tasks. Accordingly, the international recommendations for public health-promoting physical activity do not distinguish between occupational and leisure time physical activity. However, in this body of literature, attention has not been paid to the extensive documentation on occupational physical activity imposing a risk of impairment of health - in particular musculoskeletal health in terms of muscle pain. Focusing on muscle activity patterns and musculoskeletal health it is pertinent to elucidate the more specific aspects regarding exposure profiles and body regional pain. Static sustained muscle contraction for prolonged periods often occurs in the neck/shoulder area during occupational tasks and may underlie muscle pain development in spite of rather low relative muscle load. Causal mechanisms include a stereotype recruitment of low threshold motor units (activating type 1 muscle fibers) characterized by a lack of temporal as well as spatial variation in recruitment. In contrast during physical activities at leisure and sport the motor recruitment patterns are more dynamic including regularly relatively high muscle forces - also activating type 2 muscles fibers - as well as periods of full relaxation even of the type 1 muscle fibers. Such activity is unrelated to muscle pain development if adequate recovery is granted. However, delayed muscle soreness may develop following intensive eccentric muscle activity (e.g. down-hill skiing) with peak pain levels in thigh muscles 1-2 days after the exercise bout and a total recovery within 1 week. This acute pain profile is in contrast to the chronic muscle pain profile related to repetitive monotonous work tasks. The painful muscles show adverse functional, morphological, hormonal, as well as metabolic characteristics. Of note is that intensive muscle strength training actually may rehabilitate painful muscles, which has recently been repeatedly proven in randomized controlled trials. With training the maximal muscle activation and strength can be shown to recover, and consequently allow for decreased relative muscle load during occupational repetitive work tasks. Exercise training induces adaptation of metabolic and stress-related mRNA and protein responses in the painful muscles, which is in contrast to the responses evoked during repetitive work tasks per se. Copyright © 2014 Elsevier Ltd. All rights reserved.
Cognitive Assessment of Movement-Based Computer Games
NASA Technical Reports Server (NTRS)
Kearney, Paul
2008-01-01
This paper examines the possibility that dance games such as Dance Dance Revolution or StepMania enhance the cognitive abilities that are critical to academic achievement. These games appear to place a high cognitive load on working memory requiring the player to convert a visual signal to a physical movement up to 7 times per second. Players see a pattern of directions displayed on the screen and they memorise these as a dance sequence. Other researchers have found that attention span and memory ability, both cognitive abilities required for academic achievement, are improved through the use of physical movement and exercise. This paper reviews these claims and documents tool development for on-going research by the author.
The Employer Perspective on Sustainable Employability in the Construction Industry.
Tonnon, Susanne C; van der Veen, Rozan; Westerman, Marjan J; Robroek, Suzan J W; van der Ploeg, Hidde P; van der Beek, Allard J; Proper, Karin I
2017-01-01
To determine the measures employers in the construction industry take to promote sustainable employability, the barriers and facilitators that influence implementation and employer needs. Questionnaire among 499 employers and interviews with 17 employers. Employers expressed a need for alternative jobs for workers who can no longer perform physically demanding tasks, as well as means to stimulate proactive employee behavior. Measures frequently targeted the work environment (95%) and employee health (79%), less frequently personal development (63%) and organization (65%). Implementation was influenced by economic factors, rules and regulations, client demands, employee demands, company vision, company culture, and time/manpower/expertise. Implementation of measures aimed at reducing physical load and the promotion of personal development are needed.
NASA Astrophysics Data System (ADS)
Tripathy, Satchidananda; Dehury, Janaki; Mishra, Debasmita
2016-02-01
Natural fiber reinforced polymer composites are being used frequently for variety of engineering applications due to many of their advantages like ease of availability, low density, low production cost and good mechanical properties but natural fibers are more or less hydrophilic in nature. Therefore, an investigation has been carried out to make better utilization of a class of natural fiber that is date palm stem fiber, for making a wide range of products. Attempts have been made in this research work to study the effect of fiber loading on the physical, mechanical and water absorption behaviour of treated and untreated short fiber based epoxy composites. Composites of various compositions of different amounts of fiber loading are fabricated by simple hand lay-up technique. It has been observed that there is a significant effect of surface treatment of fibers on the overall properties of composites. Further enhancement of properties with lower water absorption rate was attained with glass fiber-epoxy based hybrid composites.
Haukka, E; Leino-Arjas, P; Viikari-Juntura, E; Takala, E-P; Malmivaara, A; Hopsu, L; Mutanen, P; Ketola, R; Virtanen, T; Pehkonen, I; Holtari-Leino, M; Nykänen, J; Stenholm, S; Nykyri, E; Riihimäki, H
2008-12-01
To examine the efficacy of a participatory ergonomics intervention in preventing musculoskeletal disorders among kitchen workers. Participatory ergonomics is commonly recommended to reduce musculoskeletal disorders, but evidence for its effectiveness is sparse. A cluster randomised controlled trial among the 504 workers of 119 kitchens in Finland was conducted during 2002-2005. Kitchens were randomised to an intervention (n = 59) and control (n = 60) group. The duration of the intervention that guided the workers to identify strenuous work tasks and to seek solutions for decreasing physical and mental workload, was 11 to 14 months. In total, 402 ergonomic changes were implemented. The main outcome measures were the occurrence of and trouble caused by musculoskeletal pain in seven anatomical sites, local fatigue after work, and sick leave due to musculoskeletal disorders. Individual level data were collected by a questionnaire at baseline and every 3 months during the intervention and 1-year follow-up period. All response rates exceeded 92%. No systematic differences in any outcome variable were found between the intervention and control groups during the intervention or during the 1-year follow-up. The intervention did not reduce perceived physical work load and no evidence was found for the efficacy of the intervention in preventing musculoskeletal disorders among kitchen workers. It may be that a more comprehensive redesign of work organisation and processes is needed, taking more account of workers' physical and mental resources.
Wanke, E M; Schmitter, J; Groneberg, D A
2012-03-01
A dance teacher teaches in various professional and amateur genres. The physical load depends on the target group and is partly submaximal or even higher. The only tool of dance teachers is their own body. There are only few other tools to facilitate such work. Therefore, keeping the body in a good health status is of great significance. Up to the present, there have been little or no data on the health status of persons teaching dance. The aim of this study is to examine the health status of persons who teach dance in order to initiate a data base for the development of further projects with a preventive medical focus. A total of 165 (f: 154, m: 11) average aged (46.1 years) dance teachers in Germany responded to a cross-section questionnaire survey. Teaching dance is for 96.6 % "the job of their dreams". Of all dance teachers 89.4 % continue to work while in pain and 85.5 % cannot afford a "longer down-time". 78.2 % state that they have paused due to a work-related disease, although 56.9 % of the respondents consider their occupation to be the cause for a disease with the answer only, seldom (44.4 %) or never (12.5 %). 4.5 % consult a medical doctor only after the self-treatment has failed. The lower extremity is the most common anatomic region in acute injuries (57.6 %) as well as in chronic complaints (58.3 %). The causes are multiple and comprise physical as well as psychic factors such as a high pressure of expectation (64.8 %) or a tight schedule/time table (43 %). 29 % of all dance teachers suffer from internal and 58 % from orthopaedic complaints. 43.1 % of them state that these complaints result from their occupation. 80.5 % make an acute injury responsible for compulsary breaks. The discrepancies between the self-perception and the findings of this investigation clearly show that the psychic and physical load in this occupation should not be underestimated. Here, further research on the social, psychic and physical health status of dance teachers is required. The results of this investigation warrant further research in the field of activity of the variable and up to now unprotected dance teacher profession in Germany. © Georg Thieme Verlag KG Stuttgart · New York.
MacNamara, Annmarie; Schmidt, Joseph; Zelinsky, Gregory J; Hajcak, Greg
2012-12-01
Working memory load reduces the late positive potential (LPP), consistent with the notion that functional activation of the DLPFC attenuates neural indices of sustained attention. Visual attention also modulates the LPP. In the present study, we sought to determine whether working memory load might exert its influence on ERPs by reducing fixations to arousing picture regions. We simultaneously recorded eye-tracking and EEG while participants performed a working memory task interspersed with the presentation of task-irrelevant fearful and neutral faces. As expected, fearful compared to neutral faces elicited larger N170 and LPP amplitudes; in addition, working memory load reduced the N170 and the LPP. Participants made more fixations to arousing regions of neutral faces and faces presented under high working memory load. Therefore, working memory load did not induce avoidance of arousing picture regions and visual attention cannot explain load effects on the N170 and LPP. Copyright © 2012 Elsevier B.V. All rights reserved.
Bennett, Ilana J; Rivera, Hannah G; Rypma, Bart
2013-05-15
Previous studies examining age-group differences in working memory load-related neural activity have yielded mixed results. When present, age-group differences in working memory capacity are frequently proposed to underlie these neural effects. However, direct relationships between working memory capacity and working memory load-related activity have only been observed in younger adults. These relationships remain untested in healthy aging. Therefore, the present study examined patterns of working memory load-related activity in 22 younger and 20 older adults and assessed the contribution of working memory capacity to these load-related effects. Participants performed a partial-trial delayed response item recognition task during functional magnetic resonance imaging. In this task, participants encoded either 2 or 6 letters, maintained them during a delay, and then indicated whether a probe was present in the memory set. Behavioral results revealed faster and more accurate responses to load 2 versus 6, with age-group differences in this load condition effect for the accuracy measure. Neuroimaging results revealed one region (medial superior frontal gyrus) that showed age-group differences in load-related activity during the retrieval period, with less (greater) neural activity for the low versus high load condition in younger (older) adults. Furthermore, for older adults, load-related activity did not vary as a function of working memory capacity. Thus, working memory-related activity varies with healthy aging, but these patterns are not due solely to working memory capacity. Neurocognitive aging theories that feature capacity will need to account for these results. Copyright © 2013 Elsevier Inc. All rights reserved.
Advanced thermal energy management: A thermal test bed and heat pipe simulation
NASA Technical Reports Server (NTRS)
Barile, Ronald G.
1986-01-01
Work initiated on a common-module thermal test simulation was continued, and a second project on heat pipe simulation was begun. The test bed, constructed from surplus Skylab equipment, was modeled and solved for various thermal load and flow conditions. Low thermal load caused the radiator fluid, Coolanol 25, to thicken due to its temperature avoided by using a regenerator-heat-exchanger. Other possible solutions modeled include a radiator heater and shunting heat from the central thermal bus to the radiator. Also, module air temperature can become excessive with high avionics load. A second preoject concerning advanced heat pipe concepts was initiated. A program was written which calculates fluid physical properties, liquid and vapor pressure in the evaporator and condenser, fluid flow rates, and thermal flux. The program is directed to evaluating newer heat pipe wicks and geometries, especially water in an artery surrounded by six vapor channels. Effects of temperature, groove and slot dimensions, and wick properties are reported.
Softened Mechanical Properties of Graphene Induced by Electric Field.
Huang, Peng; Guo, Dan; Xie, Guoxin; Li, Jian
2017-10-11
The understanding on the mechanical properties of graphene under the applications of physical fields is highly relevant to the reliability and lifetime of graphene-based nanodevices. In this work, we demonstrate that the application of electric field could soften the mechanical properties of graphene dramatically on the basis of the conductive AFM nanoindentation method. It has been found that the Young's modulus and fracture strength of graphene nanosheets suspended on the holes almost stay the same initially and then exhibit a sharp drop when the normalized electric field strength increases to be 0.18 ± 0.03 V/nm. The threshold voltage of graphene nanosheets before the onset of fracture under the fixed applied load increases with the thickness. Supported graphene nanosheets can sustain larger electric field under the same applied load than the suspended ones. The excessively regional Joule heating caused by the high electric current under the applied load is responsible for the electromechanical failure of graphene. These findings can provide a beneficial guideline for the electromechanical applications of graphene-based nanodevices.
Structural Dynamics of Electronic Systems
NASA Astrophysics Data System (ADS)
Suhir, E.
2013-03-01
The published work on analytical ("mathematical") and computer-aided, primarily finite-element-analysis (FEA) based, predictive modeling of the dynamic response of electronic systems to shocks and vibrations is reviewed. While understanding the physics of and the ability to predict the response of an electronic structure to dynamic loading has been always of significant importance in military, avionic, aeronautic, automotive and maritime electronics, during the last decade this problem has become especially important also in commercial, and, particularly, in portable electronics in connection with accelerated testing of various surface mount technology (SMT) systems on the board level. The emphasis of the review is on the nonlinear shock-excited vibrations of flexible printed circuit boards (PCBs) experiencing shock loading applied to their support contours during drop tests. At the end of the review we provide, as a suitable and useful illustration, the exact solution to a highly nonlinear problem of the dynamic response of a "flexible-and-heavy" PCB to an impact load applied to its support contour during drop testing.
Physical Weight Loading Induces Expression of Tryptophan Hydroxylase 2 in the Brain Stem
Shim, Joon W.; Dodge, Todd R.; Hammond, Max A.; Wallace, Joseph M.; Zhou, Feng C.; Yokota, Hiroki
2014-01-01
Sustaining brain serotonin is essential in mental health. Physical activities can attenuate mental problems by enhancing serotonin signaling. However, such activity is not always possible in disabled individuals or patients with dementia. Knee loading, a form of physical activity, has been found to mimic effects of voluntary exercise. Focusing on serotonergic signaling, we addressed a question: Does local mechanical loading to the skeleton elevate expression of tryptophan hydroxylase 2 (tph2) that is a rate-limiting enzyme for brain serotonin? A 5 min knee loading was applied to mice using 1 N force at 5 Hz for 1,500 cycles. A 5-min treadmill running was used as an exercise (positive) control, and a 90-min tail suspension was used as a stress (negative) control. Expression of tph2 was determined 30 min – 2 h in three brain regions ––frontal cortex (FC), ventromedial hypothalamus (VMH), and brain stem (BS). We demonstrated for the first time that knee loading and treadmill exercise upregulated the mRNA level of tph2 in the BS, while tail suspension downregulated it. The protein level of tph2 in the BS was also upregulated by knee loading and downregulated by tail suspension. Furthermore, the downregulation of tph2 mRNA by tail suspension can be partially suppressed by pre-application of knee loading. The expression of tph2 in the FC and VMH was not significantly altered with knee loading. In this study we provided evidence that peripheral mechanical loading can activate central tph2 expression, suggesting that physical cues may mediate tph2-cathalyzed serotonergic signaling in the brain. PMID:24416346
Jamniczky, Heather A; McLaughlin, Kevin; Kaminska, Malgorzata E; Raman, Maitreyi; Somayaji, Ranjani; Wright, Bruce; Ma, Irene W Y
2015-01-01
Ultrasonography is increasingly used for teaching anatomy and physical examination skills but its effect on cognitive load is unknown. This study aimed to determine ultrasound's perceived utility for learning, and to investigate the effect of cognitive load on its perceived utility. Consenting first-year medical students (n = 137) completed ultrasound training that includes a didactic component and four ultrasound-guided anatomy and physical examination teaching sessions. Learners then completed a survey on comfort with physical examination techniques (three items; alpha = 0.77), perceived utility of ultrasound in learning (two items; alpha = 0.89), and cognitive load on ultrasound use [measured with a validated nine-point scale (10 items; alpha = 0.88)]. Learners found ultrasound useful for learning for both anatomy and physical examination (mean 4.2 ± 0.9 and 4.4 ± 0.8, respectively; where 1 = very useless and 5 = very useful). Principal components analysis on the cognitive load survey revealed two factors, "image interpretation" and "basic knobology," which accounted for 60.3% of total variance. Weighted factor scores were not associated with perceived utility in learning anatomy (beta = 0.01, P = 0.62 for "image interpretation" and beta = -0.04, P = 0.33 for "basic knobology"). However, factor score on "knobology" was inversely associated with perceived utility for learning physical examination (beta = -0.06; P = 0.03). While a basic introduction to ultrasound may suffice for teaching anatomy, more training may be required for teaching physical examination. Prior to teaching physical examination skills with ultrasonography, we recommend ensuring that learners have sufficient knobology skills. © 2014 American Association of Anatomists.
Factors associated with work-related fatigue and recovery in hospital nurses working 12-hour shifts.
Han, Kihye; Trinkoff, Alison M; Geiger-Brown, Jeanne
2014-10-01
Nurse fatigue threatens both nurse and patient safety; fatigue affects nurses' neurocognitive functioning and hinders their work performance. The authors assessed the association of work and non-work factors with acute and chronic fatigue and intershift recovery among hospital nurses working 12-hour shifts. This study used survey data from 80 nurses who provided full-time direct patient care on medical-surgical and critical care units in a large teaching hospital. Psychological job demands (e.g., work load and social support from supervisor or coworker) were significantly associated with acute and chronic fatigue and intershift recovery. Rotating shifts were significantly related to acute fatigue. Findings suggest the need for a comprehensive approach to fatigue management, including organizational support to provide healthful work schedules and favorable nursing work environments, fewer psychological and physical demands, and assistance to improve nurses' sleep quality and quantity. [Workplace Health Saf 2014;62(10):409-414.]. Copyright 2014, SLACK Incorporated.
Ion current as a precise measure of the loading rate of a magneto-optical trap
DOE Office of Scientific and Technical Information (OSTI.GOV)
Jiang, W.; Bailey, K.; Lu, Z. -T.
2014-01-01
We have demonstrated that the ion current resulting from collisions between metastable krypton atoms in a magneto-optical trap can be used to precisely measure the trap loading rate. We measured both the ion current of the abundant isotope Kr-83 (isotopic abundance = 11%) and the single-atom counting rate of the rare isotope Kr-85 (isotopic abundance similar to 1 x 10(-11)), and found the two quantities to be proportional at a precision level of 0.9%. This work results in a significant improvement in using the magneto-optical trap as an analytical tool for noble-gas isotope ratio measurements, and will benefit both atomicmore » physics studies and applications in the earth sciences. (C) 2014 Optical Society of America« less
Is burnout related to allostatic load?
Langelaan, Saar; Bakker, Arnold B; Schaufeli, Wilmar B; van Rhenen, Willem; van Doornen, Lorenz J P
2007-01-01
Burnout has a negative impact on physical health, but the mechanisms underlying this relation remain unclear. To elucidate these mechanisms, possible mediating physiological systems or risk factors for adverse health in burned-out employees should be investigated. The aim of the present study among 290 Dutch managers was to explore whether allostatic load mediates the relationship between burnout and physical health. Burned-out managers, as identified with the Maslach Burnout Inventory General Survey (MBI-GS), were compared with a healthy control group with regard to their allostatic load. The allostatic load index included eight parameters: Body-mass index (BMI), systolic and diastolic blood pressure (SBP and DBP), C-reactive protein (CRP), high-density lipoprotein (HDL), cholesterol, glycosylated hemoglobin (HbA1C) and glucose. Contrary to expectations, burned-out managers did not differ from healthy managers with regard to their scores on the allostatic load index. An additional analysis, using groups of managers in the extreme deciles of exhaustion (the core symptom of burnout), did also not reveal differences in allostatic load. Burnout seems not to be associated with this proxy measure of allostatic load. The mediating physiological mechanisms between burnout and objective physical health remain to be elucidated.
Gender and ergonomics: a case study on the 'non-formal' work of women nurses.
Salerno, Silvana; Livigni, Lucilla; Magrini, Andrea; Talamanca, Irene Figà
2012-01-01
Women's work activities are often characterised by 'non-formal actions' (such as giving support). Gender differences in ergonomics may be due to this peculiarity. We applied the method of organisational congruencies (MOC) to ascertain the 'non-formal' work portion of nurses employed in three hospital units (haematology, emergency room and general medicine) during the three work shifts in a major University Hospital in Rome, Italy. We recorded a total of 802 technical actions performed by nine nurses in 72 h of work. Twenty-six percent of the actions in direct patient's care were communicative actions (mainly giving psychological support) while providing physical care. These 'double actions' are often not considered to be a formal part of the job by hospital management. In our case study, the 'non-formal' work of nurses (psychological support) is mainly represented by double actions while taking physical care of the patients. The dual task paradigm in gender oriented research is discussed in terms of its implications in prevention in occupational health. The main purpose of the study was to assess all the formal and non-formal activities of women in the nursing work setting. Offering psychological support to patients is often not considered to be a formal part of the job. Our case study found that nurses receive no explicit guidelines on this activity and no time is assigned to perform it. In measuring the burden of providing psychological support to patients, we found that this is often done while nurses are performing tasks of physical care for the patients (double actions). The article discusses the significance of non-formal psychological work load of women nurses through double actions from the ergonomic point view.
Rinne, Marjo; Garam, Sanna; Häkkinen, Arja; Ylinen, Jari; Kukkonen-Harjula, Katriina; Nikander, Riku
2016-05-01
Cervicogenic headache and migraine are common causes of visits to physicians and physical therapists. Few randomized trials utilizing active physical therapy and progressive therapeutic exercise have been previously published. The existing evidence on active treatment methods supports a moderate effect on cervicogenic headache. The aim of this study is to investigate whether a progressive, group-based therapeutic exercise program decreases the intensity and frequency of chronic headache among women compared with a control group receiving a sham dose of transcutaneous electrical nerve stimulation (TENS) and stretching exercises. A randomized controlled trial with 6-month intervention and follow-up was developed. The participants were randomly assigned to either a treatment group or a control group. The study is being conducted at 2 study centers. The participants are women aged 18 to 60 years with chronic cervicogenic headache or migraine. The treatment group's exercise program consisted of 6 progressive therapeutic exercise modules, including proprioceptive low-load progressive craniocervical and cervical exercises and high-load exercises for the neck muscles. The participants in the control group received 6 individually performed sham TENS treatment sessions. The primary outcome is the intensity of headache. The secondary outcomes are changes in frequency and duration of headache, neck muscle strength, neck and shoulder flexibility, impact of headache on daily life, neck disability, fear-avoidance beliefs, work ability, and quality of life. Between-group differences will be analyzed separately at 6, 12, and 24 months with generalized linear mixed models. In the case of count data (eg, frequency of headache), Poisson or negative binomial regression will be used. The therapists are not blinded. The effects of specific therapeutic exercises on frequency, intensity, and duration of chronic headache and migraine will be reported. © 2016 American Physical Therapy Association.
Prevalence of burnout syndrome in clinical nurses at a hospital of excellence.
Ribeiro, Vivian F; Filho, Celso Ferreira; Valenti, Vitor E; Ferreira, Marcelo; de Abreu, Luiz Carlos; de Carvalho, Tatiana Dias; Xavier, Valdelias; de Oliveira Filho, JapyAngeli; Gregory, Pedro; Leão, Eliseth Ribeiro; Francisco, Natascha G; Ferreira, Celso
2014-01-01
Burnout syndrome can be defined as long-term work stress resulting from the interaction between constant emotional pressure associated with intense interpersonal involvement for long periods of time and personal characteristics. We investigated the prevalence/propensity of Burnout syndrome in clinical nurses, and the factors related to Burnout syndrome-associated such as socio-demographic characteristics, work load, social and family life, leisure activities, extra work activities, physical activities, and work-related health problems. We conducted a cross-sectional, quantitative, prospective epidemiological study with 188 surgical clinic nurses. We used the Maslach Burnout Inventory (MBI), which is a socio-demographic questionnaire and the most widely used instrument to assess Burnout syndrome (three basic dimensions: emotional exhaustion, despersonalization and professional underachievement). The socio-demographic profile questionnaire wascomposed of questions regarding identification, training, time at work, work characteristics and personal circumstances. The prevalence of Burnout syndrome was higher (10.1%) and 55, 4% of subjects had a propensity to develop this syndrome. The analysis of the socio-demographic profile of the nurse sample studied showed that most nurses were childless married women, over 35 years of age, working the day shift for 36 hours weekly on average, with 2-6 years of post-graduation experience, and without extra employments. Factors such as marital status, work load, emotion and work related stress aggravated the onset of the syndrome. The prevalence and propensity of Burnout syndrome were high. Some factors identified can be useful for the adoption of preventive actions in order to decrease the prevalence of the clinical nurses Burnout syndrome.
Prevalence of burnout syndrome in clinical nurses at a hospital of excellence
2014-01-01
Background Burnout syndrome can be defined as long-term work stress resulting from the interaction between constant emotional pressure associated with intense interpersonal involvement for long periods of time and personal characteristics. We investigated the prevalence/propensity of Burnout syndrome in clinical nurses, and the factors related to Burnout syndrome-associated such as socio-demographic characteristics, work load, social and family life, leisure activities, extra work activities, physical activities, and work-related health problems. Method We conducted a cross-sectional, quantitative, prospective epidemiological study with 188 surgical clinic nurses. We used the Maslach Burnout Inventory (MBI), which is a socio-demographic questionnaire and the most widely used instrument to assess Burnout syndrome (three basic dimensions: emotional exhaustion, despersonalization and professional underachievement). The socio-demographic profile questionnaire wascomposed of questions regarding identification, training, time at work, work characteristics and personal circumstances. Results The prevalence of Burnout syndrome was higher (10.1%) and 55, 4% of subjects had a propensity to develop this syndrome. The analysis of the socio-demographic profile of the nurse sample studied showed that most nurses were childless married women, over 35 years of age, working the day shift for 36 hours weekly on average, with 2-6 years of post-graduation experience, and without extra employments. Factors such as marital status, work load, emotion and work related stress aggravated the onset of the syndrome. Conclusion The prevalence and propensity of Burnout syndrome were high. Some factors identified can be useful for the adoption of preventive actions in order to decrease the prevalence of the clinical nurses Burnout syndrome. PMID:24860618
1989-12-27
is important to note also that as interdisciplinary studies have gained in -kj ’- popularity, theories incorporating physical and behavi6ral hypothesis...have gained strength due to approaches which focus multiple measures on single factors. Th( study of military sustained performance/operations...related fields of study . These environmental and interdisciplinary areas of study are typically sleep deprivation, work load, exercise physiology
The Effect of Physical Load and Environment on Soldier Performance
2014-02-01
when walking over obstacles compared with standing still with and without a load. Knapik et al. (1990) found significant decrements in military...load carriage (34–61 kg carried 20 km) led to decrements in subsequent physical performance but not in cognitive ability. Crowell et al. (1999) found...with a simultaneous visual navigation task was thought to be advantageous; Wickens’s (1984) multiple resource theory stated that different tasks can
Work-Related Upper Limb Disorders: A Case Report
Stoyneva, Zlatka Borisova; Dermendjiev, Svetlan; Dermendjiev, Tihomir; Dobrev, Hristo
2015-01-01
In this study the complex interrelationship between physical factors, job stress, lifestyle and genetic factors on symptoms of work-related musculoskeletal disorders of the upper limbs is demonstrated by a case report and discussion of the literature. A 58 year old woman with long lasting complaints of the upper limbs with increasing intensity and duration, generalisation, combined with skin thickness, Raynaud’s phenomenon, joint disorders, arterial and pulmonary hypertension, metabolic lipid dysfunctions is presented. Occupational history proves continuous duration of service at a job with occupational physical static load with numerous repetitive monotonous systematic motions of fingers and hands as a weaver of Persian rugs followed by work at an automated loom and variable labour activities. Though the complaints dated since the time she was a manual weaver, the manifestations of generalized joint degenerative changes, system sclerosis with Raynaud’s phenomenon with similar upper extremities signs and symptoms discount upper limbs musculoskeletal disorder as caused only or mainly by occupational risk factors. The main principles and criteria for occupational diagnosis of musculoskeletal upper limb disorders and legislative requirements for their reglamentation are discussed. PMID:27275213
Functional connectivity among multi-channel EEGs when working memory load reaches the capacity.
Zhang, Dan; Zhao, Huipo; Bai, Wenwen; Tian, Xin
2016-01-15
Evidence from behavioral studies has suggested a capacity existed in working memory. As the concept of functional connectivity has been introduced into neuroscience research in the recent years, the aim of this study is to investigate the functional connectivity in the brain when working memory load reaches the capacity. 32-channel electroencephalographs (EEGs) were recorded for 16 healthy subjects, while they performed a visual working memory task with load 1-6. Individual working memory capacity was calculated according to behavioral results. Short-time Fourier transform was used to determine the principal frequency band (theta band) related to working memory. The functional connectivity among EEGs was measured by the directed transform function (DTF) via spectral Granger causal analysis. The capacity was 4 calculated from the behavioral results. The power was focused in the frontal midline region. The strongest connectivity strengths of EEG theta components from load 1 to 6 distributed in the frontal midline region. The curve of DTF values vs load numbers showed that DTF increased from load 1 to 4, peaked at load 4, then decreased after load 4. This study finds that the functional connectivity between EEGs, described quantitatively by DTF, became less strong when working memory load exceeded the capacity. Copyright © 2015 Elsevier B.V. All rights reserved.
A process for providing positive primary control power by wind turbines
NASA Astrophysics Data System (ADS)
Marschner, V.; Michael, J.; Liersch, J.
2014-12-01
Due to the increasing share of wind energy in electricity generation, wind turbines have to fulfil additional requirements in the context of grid integration. The paper examines to which extent wind turbines can provide positive control power following the related grid code. The additional power has to be obtained from the rotating flywheel mass of the wind turbine's rotor. A simple physical model is developed that allows to draw conclusions about appropriate concepts by means of a dynamic simulation of the variables rotational speed, torque, power output and rotor power. The paper discusses scenarios to provide control power. The supply of control power at partial load is examined in detail using simulations. Under partial load conditions control power can be fed into the grid for a short time. Thereby the rotational speed drops so that aerodynamic efficiency decreases and feed-in power is below the initial value after the control process. In this way an unfavourable situation for the grid control is produced, therefore the paper proposes a modified partial load condition with a higher rotational speed. By providing primary control power the rotor is delayed to the optimum rotational speed so that more rotational energy can be fed in and fed-in power can be increased persistently. However, as the rotor does not operate at optimum speed, a small amount of the energy yield is lost. Finally, the paper shows that a wind farm can combine these two concepts: A part of the wind turbines work under modified partial load conditions can compensate the decrease of power of the wind turbines working under partial load conditions. Therefore the requested control power is provided and afterwards the original value of power is maintained.
Dasgupta, Queeny; Movva, Sahitya; Chatterjee, Kaushik; Madras, Giridhar
2017-08-07
This work reports the synthesis of a novel, aspirin-loaded, linear poly (anhydride ester) and provides mechanistic insights into the release of aspirin from this polymer for anti-inflammatory activity. As compared to conventional drug delivery systems that rely on diffusion based release, incorporation of bioactives in the polymer backbone is challenging and high loading is difficult to achieve. In the present study, we exploit the pentafunctional sugar alcohol (xylitol) to provide sites for drug (aspirin) attachment at its non-terminal OH groups. The terminal OH groups are polymerized with a diacid anhydride. The hydrolysis of the anhydride and ester bonds under physiological conditions release aspirin from the matrix. The resulting poly(anhydride ester) has high drug loading (53%) and displays controlled release kinetics of aspirin. The polymer releases 8.5 % and 20%, of the loaded drug in one and four weeks, respectively and has a release rate constant of 0.0035h -0.61 . The release rate is suitable for its use as an anti-inflammatory agent without being cytotoxic. The polymer exhibits good cytocompatibility and anti-inflammatory properties and may find applications as injectable or as an implantable bioactive material. The physical insights into the release mechanism can provide development of other drug loaded polymers. Copyright © 2017 Elsevier B.V. All rights reserved.
González-Galarzo, M Carmen; García, Ana M; Estarlich, Marisa; García García, Francisco; Esplugues, Ana; Rodríguez, Paz; Rebagliato, Marisa; Ballester, Ferran
2009-01-01
To describe the prevalence of exposure to occupational risks among pregnant women and analyze its relationship with personal and occupational characteristics using information collected in the Childhood and Environment (Infancia y Medio Ambiente [INMA])-Valencia cohort study. The INMA-Valencia cohort study started in 2004 with 855 pregnant women living in Valencia, Spain. Data on sociodemographic variables (age, education and country of birth) and occupational conditions (activity, occupation, type of contract, working hours and self-reported occupational exposure to physical load and psychosocial, physical, chemical and biological risks) in women with paid employment during pregnancy (n=649) were collected through face-to-face interviews with a structured questionnaire in week 32 of pregnancy. The prevalences of reported exposure to physical and psychosocial load and to physical pollutants (including non-ionizing radiations) were 56%, 63% and 62%, respectively. The prevalence of reported exposure to chemicals (including cleaning products) and biological pollutants was 22% and 6%, respectively. In general, the characteristics most closely associated with exposure to occupational risks were younger age, non-Spanish nationality, lower education, having a temporary contract or being self-employed. This study is the first to quantify the prevalence of exposure to occupational risks during pregnancy in a Spanish population-based sample. According to the data observed, surveillance and control actions should be intensified in pregnant workers, as some of the observed occupational exposures have been consistently associated with detrimental reproductive and developmental effects.
NASA Astrophysics Data System (ADS)
Nemec, Patrik; Malcho, Milan
2018-06-01
This work deal with experimental measurement and calculation cooling efficiency of the cooling device working with a heat pipe technology. The referred device in the article is cooling device capable transfer high heat fluxes from electric elements to the surrounding. The work contain description, working principle and construction of cooling device. The main factor affected the dissipation of high heat flux from electronic elements through the cooling device to the surrounding is condenser construction, its capacity and option of heat removal. Experimental part describe the measuring method cooling efficiency of the cooling device depending on ambient temperature in range -20 to 40°C and at heat load of electronic components 750 W. Measured results are compared with results calculation based on physical phenomena of boiling, condensation and natural convection heat transfer.
Factors associated with dysmenorrhea among workers in French poultry slaughterhouses and canneries.
Messing, K; Saurel-Cubizolles, M J; Bourgine, M; Kaminski, M
1993-05-01
The food and agriculture industry employs 15% of the female industrial work force in France. Workers in this industry are exposed to a variety of environmental and organizational constraints: cold, uncomfortable postures, assembly-line work, irregular schedules. In 1987 to 1988, a medical examination and questionnaire were administered to 726 menstruating women who had not been pregnant during the 2 previous years, as part of a study of French workers in 17 poultry slaughterhouses and 6 canning factories. Dysmenorrhea during the previous year was more prevalent among younger women and smokers, and less prevalent among users of oral contraceptives. After adjustment for nonoccupational variables, dysmenorrhea was significantly related to several parameters expressing cold exposure and physical work load. Other parameters such as job satisfaction and hours of domestic work were not associated with dysmenorrhea.
Thomas, Shindu C; Sharma, Harshita; Rawat, Purnima; Verma, Anita K; Leekha, Ankita; Kumar, Vijay; Tyagi, Aakriti; Gurjar, Bahadur S; Iqbal, Zeenat; Talegaonkar, Sushama
2016-10-01
The present work evaluates the synergistic anticancer efficacy of bioactive Hydroxyapatite (HA) nanoparticles (HA NPs) loaded with Bendamustine HCl. Hydroxyapatite is a material with an excellent biological compatibility, a well-known fact which was also supported by the results of the Hemolytic studies and a high IC50 value observed in the MTT assay. HA NPs were prepared by the chemical precipitation method and loaded with the drug via physical adsorption. In-vitro release study was performed, which confirmed the sustained release of the drug from the drug loaded HA NPs. MTT assay, Cell Uptake and FACS studies on JURKAT E6.1 cell line and in-vivo pharmacokinetic studies in Wistar rats revealed that the drug loaded HA NPs could be easily internalized by the cells and release drug in a sustained manner. The drug loaded HA NPs showed cytotoxicity similar to the drug solution at 1/10th of the drug content, which indicates a possible synergism between the activity of the anticancer drug and calcium ions derived from the carrier. An increase in intracellular Ca(2+) ions is reported to induce apoptosis in cells. Tumor regression study in Balb/c mice Ehrlich's ascites model presented a similar synergistic efficacy. The drug solution was able to decrease the tumor volume by half, while the drug loaded HA NPs reduced the tumor size by 6 times. Copyright © 2016 Elsevier B.V. All rights reserved.
NASA Technical Reports Server (NTRS)
Genc, K. O.; Gopalakrishnan, R.; Kuklis, M. M.; Maender, C. C.; Rice, A. J.; Cavanagh, P. R.
2009-01-01
Despite the use of exercise countermeasures during long-duration space missions, bone mineral density (BMD) and predicted bone strength of astronauts continue to show decreases in the lower extremities and spine. This site-specific bone adaptation is most likely caused by the effects of microgravity on the mechanical loading environment of the crew member. There is, therefore, a need to quantify the mechanical loading experienced on Earth and on-orbit to define the effect of a given "dose" of loading on bone homeostasis. Gene et al. recently proposed an enhanced DLS (EDLS) model that, when used with entire days of in-shoe forces, takes into account recently developed theories on the importance of factors such as saturation, recovery, and standing and their effects on the osteogenic response of bone to daily physical activity. This algorithm can also quantify the tinting and type of activity (sit/unload, stand, walk, run or other loaded activity) performed throughout the day. The purpose of the current study was to use in-shoe force measurements from entire typical work days on Earth and on-orbit in order to quantify the type and amount of loading experienced by crew members. The specific aim was to use these measurements as inputs into the EDLS model to determine activity timing/type and the mechanical "dose" imparted on the musculoskeletal system of crew members and relate this dose to changes in bone homeostasis.
NASA Technical Reports Server (NTRS)
Machablishvili, O. G.
1980-01-01
The thermal state of women during the effect of high air temperature and relative humidity with a varying degree of physical loads was studied. Parameters for air temperature, relative humidity, and air movement were established. It was established that in women the thermo-regulatory stress occurs at lower air temperatures and with lower physical loads than in men. The accumulation of heat in women was revealed with lower air temperature than in men. It is concluded that to preserve the normal physiological state of the female organism it is necessary to create more favorable microclimate conditions and decrease the physical loads.
Huang, Kuo-Yuan; Lin, Ruey-Mo; Lee, Yung-Ling; Li, Jenq-Daw
2009-12-01
Few studies have investigated the factors related to the disability and physical function in degenerative lumbar spondylolisthesis using axially loaded magnetic resonance imaging (MRI). Therefore, we aimed to investigate the effect of axial loading on the morphology of the spine and the spinal canal in patients with degenerative spondylolisthesis of L4-5 and to correlate morphologic changes to their disability and physical functions. From March 2003 to January 2004, 32 consecutive cases (26 females, 6 males) with degenerative L4-5 spondylolisthesis, grade 1-2, intermittent claudication, and low back pain without sciatica were included in this study. All patients underwent unloaded and axially loaded MRI of the lumbo-sacral spine in supine position to elucidate the morphological findings and to measure the parameters of MRI, including disc height (DH), sagittal translation (ST), segmental angulation (SA), dural sac cross-sectional area (DCSA) at L4-5, and lumbar lordotic angles (LLA) at L1-5 between the unloaded and axially loaded condition. Each patient's disability was evaluated by the Oswestry Disability Index (ODI) questionnaire, and physical functioning (PF) was evaluated by the Physical Function scale proposed by Stucki et al. (Spine 21:796-803, 1996). Three patients were excluded due to the presence of neurologic symptoms found with the axially loaded MRI. Finally, a total of 29 (5 males, 24 females) consecutive patients were included in this study. Comparisons and correlations were done to determine which parameters were critical to the patient's disability and PF. The morphologies of the lumbar spine changed after axially loaded MRI. In six of our patients, we observed adjacent segment degeneration (4 L3-L4 and 2 L5-S1) coexisting with degenerative spondylolisthesis of L4-L5 under axially loaded MRI. The mean values of the SA under pre-load and post-load were 7.14 degrees and 5.90 degrees at L4-L5 (listhetic level), respectively. The mean values of the LLA under pre-load and post-load were 37.03 degrees and 39.28 degrees , respectively. There were significant correlations only between the ODI, PF, and the difference of SA, and between PF and the post-loaded LLA. The changes in SA (L4-L5) during axial loading were well correlated to the ODI and PF scores. In addition, the LLA (L1-L5) under axial loading was well correlated to the PF of patients with degenerative L4-L5 spondylolisthesis. We suggest that the angular instability of the intervertebral disc may play a more important role than neurological compression in the pathogenesis of disability in degenerative lumbar spondylolisthesis.
Choi, Jong Seo; Kim, Dong Wuk; Kim, Dong Shik; Kim, Jong Oh; Yong, Chul Soon; Cho, Kwan Hyung; Youn, Yu Seok; Jin, Sung Giu; Choi, Han-Gon
2016-10-01
To develop a novel neomycin sulfate-loaded hydrogel dressing (HD), numerous neomycin sulfate-loaded HDs were prepared with various amounts of polyvinyl alcohol (PVA), polyvinyl pyrrolidone (PVP) and sodium alginate (SA) using freeze-thawing technique, and their physical dressing properties, drug release, in vivo wound curing and histopathology in diabetic-induced rats were assessed. SA had a positive effect on a swelling capacity, but a negative effect on the physical dressing properties and drug release of HD. However, PVP did the opposite. In particular, the neomycin sulfate-loaded HD composed of drug, PVA, PVP and SA at the weight ratio of 1/10/0.8/0.8 had excellent swelling and bioadhesive capacity, good elasticity and fast drug release. Moreover, this HD gave more improved wound curing effect compared to the commercial product, ensured the disappearance of granulation tissue and recovered the wound tissue to normal. Therefore, this novel neomycin sulfate-loaded HD could be an effective pharmaceutical product for the treatment of wounds.
Operational load estimation of a smart wind turbine rotor blade
NASA Astrophysics Data System (ADS)
White, Jonathan R.; Adams, Douglas E.; Rumsey, Mark A.
2009-03-01
Rising energy prices and carbon emission standards are driving a fundamental shift from fossil fuels to alternative sources of energy such as biofuel, solar, wind, clean coal and nuclear. In 2008, the U.S. installed 8,358 MW of new wind capacity increasing the total installed wind power by 50% to 25,170 MW. A key technology to improve the efficiency of wind turbines is smart rotor blades that can monitor the physical loads being applied by the wind and then adapt the airfoil for increased energy capture. For extreme wind and gust events, the airfoil could be changed to reduce the loads to prevent excessive fatigue or catastrophic failure. Knowledge of the actual loading to the turbine is also useful for maintenance planning and design improvements. In this work, an array of uniaxial and triaxial accelerometers was integrally manufactured into a 9m smart rotor blade. DC type accelerometers were utilized in order to estimate the loading and deflection from both quasi-steady-state and dynamic events. A method is presented that designs an estimator of the rotor blade static deflection and loading and then optimizes the placement of the sensor(s). Example results show that the method can identify the optimal location for the sensor for both simple example cases and realistic complex loading. The optimal location of a single sensor shifts towards the tip as the curvature of the blade deflection increases with increasingly complex wind loading. The framework developed is practical for the expansion of sensor optimization in more complex blade models and for higher numbers of sensors.
Cognitive task demands, self-control demands and the mental well-being of office workers.
Bridger, Robert S; Brasher, Kate
2011-09-01
The cognitive task demands of office workers and the self-control demands of their work roles were measured in a sample of 196 employees in two different office layouts using a self-report questionnaire, which was circulated electronically. Multiple linear regression analysis revealed that both factors were associated with mental well-being, but not with physical well-being, while controlling for exposure to psychosocial stressors. The interaction between cognitive task demands and self-control demands had the strongest association with mental well-being, suggesting that the deleterious effect of one was greater when the other was present. An exploratory analysis revealed that the association was stronger for employees working in a large open-plan office than for those working in smaller offices with more privacy. Frustration of work goals was the cognitive task demand having the strongest negative impact on mental well-being. Methodological limitations and scale psychometrics (particularly the use of the NASA Task Load Index) are discussed. STATEMENT OF RELEVANCE: Modern office work has high mental demands and low physical demands and there is a need to design offices to prevent adverse psychological reactions. It is shown that cognitive task demands interact with self-control demands to degrade mental well-being. The association was stronger in an open-plan office.
Mélan, Claudine; Cascino, Nadine
2014-01-01
The present contribution presents two field studies combining tools and methods from cognitive psychology and from occupational psychology in order to perform a thorough investigation of workload in employees. Cognitive load theory proposes to distinguish different load categories of working memory, in a context of instruction. Intrinsic load is inherent to the task, extraneous load refers to components of a learning environment that may be modified to reduce total load, and germane load enables schemas construction and thus efficient learning. We showed previously that this theoretical framework may be successfully extended to working memory tasks in non-instructional designs. Other theoretical models, issued from the field of occupational psychology, account for an individual's perception of work demands or requirements in the context of different psychosocial features of the (work) environment. Combining these approaches is difficult as workload assessment by job-perception questionnaires explore an individual's overall job-perception over a large time-period, whereas cognitive load investigations in working memory tasks are typically performed within short time-periods. We proposed an original methodology enabling investigation of workload and load factors in a comparable time-frame. We report two field studies investigating workload on different shift-phases and between work-shifts, with two custom-made tools. The first one enabled workload assessment by manipulating intrinsic load (task difficulty) and extraneous load (time pressure) in a working-memory task. The second tool was a questionnaire based on the theoretical concepts of work-demands, control, and psychosocial support. Two additional dimensions suspected to contribute to job-perception, i.e., work-family conflicts and availability of human and technical resources were also explored. Results of workload assessments were discussed in light of operators' alertness and job-performance.
NASA Astrophysics Data System (ADS)
Triantis, Dimos; Stavrakas, Ilias; Hloupis, George; Ninos, Konstantinos; Vallianatos, Filippos
2013-04-01
The detection of Acoustic Emissions (AE) and Electrical Signals (ES) has been proved as a valuable experimental method to characterize the mechanical status of marble specimens when subjected to mechanical stress. In this work, marble specimens with dimensions 10cm x 4cm x 4cm where subjected to sequential loading cycles. The maximum stress of each loading was near the vicinity of fracture and was maintained for a relatively long time (th=200s). Concurrently to the mechanical tests, AE and ES were recorded. Specifically, two AE sensors and five ES sensors were installed on the surface of the specimens and the detected emissions were stored on a PC. The recordings show that AE and ES provide information regarding the damage spreading and location in the bulk of the specimen. Specifically, when the mechanical stress was maintained constant at the high stress value during each loading cycle the cumulative number of the AE hits become gradually less reaching a minimum after the first three loading cycles, indicating the existence of the Kaiser effect. During the eighth loading cycle the AE hits show a significant increase that became maximum at the ninth cycle before where failure occured. A similar behavior was observed for the cumulative energy. A b-value analysis was conducted following both Aki's and Gutenberg-Richter relations on the amplitudes of the AE hits. The b-values were found to increase during the three first loading cycles while consequently they were practically constant until reaching the two final loading cycles where they became gradually lower. The ES significantly increases during the stress increase of each cycle and gradually restores at a background level when the applied stress is maintained constant near the vicinity of fracture. It was observed that the background restoration level becomes gradually higher during the first four loading cycles. Consequently, during the next three loading cycles the background level is maintained practically constant. During the two final loading cycles the background restoration level significantly increases indicating the upcoming fracture. Acknowledgments. This work was supported by the THALES Program of the Ministry of Education of Greece and the European Union in the framework of the project entitled "Integrated understanding of Seismicity, using innovative Methodologies of Fracture mechanics along with Earthquake and non extensive statistical physics - Application to the geodynamic system of the Hellenic Arc. SEISMO FEAR HELLARC".
Finne-Soveri, H; Sørbye, L W; Jonsson, P V; Carpenter, G I; Bernabei, R
2008-06-01
The plurality of definition of faecal incontinence (FI) complicates the cross-national comparisons between studies conducted in the area. The aim of the study was to investigate work-load and subjective care-giver burden associated with FI, among home-care patients, in Europe. In this cross-sectional retrospective study, a random sample of 4010 RAI-HC assessments were collected during 2001-02 from home care patients aged 65 years and over (74% females; age 82.8 +/- 7.2 years) in Czech Republic, Denmark, Finland, France, Germany, Iceland, Italy, The Netherlands, Norway, Sweden and United Kingdom. Of the 4010 individuals, 411 (10.3%) suffered from FI (range 1.1-30.8% from site to site). The factors significantly associated with faecal incontinence were diarrhoea [odds ratio (OR) 10.3, 95% confidence interval (CI) 6.590-15.96], urinary incontinence (OR 3.99, 95% CI 2.991-5.309) and pressure ulcers (OR 3.15, 95% CI 2.196-4.512) together with severe impairments in physical (OR 4.25, 95% CI 2.872-6.295) and cognitive (OR 3.76, 95% CI 2.663-5.304) functions. High use of working hours of the visiting nurses (OR 2.04, 95% CI 1.221-3.414) and home health carers (OR 2.40, 95% CI 1.289-4.470) were additionally associated with faecal incontinence. Use of five or more medications was an inversely associated with FI (OR 0.62, 95% CI 0.473-0.820). The additional work load associated with faecal incontinence comprises considerable numbers of formal health care hours and should be taken into account when planning home health services for the older in home care patients.
Ensemble coding remains accurate under object and spatial visual working memory load.
Epstein, Michael L; Emmanouil, Tatiana A
2017-10-01
A number of studies have provided evidence that the visual system statistically summarizes large amounts of information that would exceed the limitations of attention and working memory (ensemble coding). However the necessity of working memory resources for ensemble coding has not yet been tested directly. In the current study, we used a dual task design to test the effect of object and spatial visual working memory load on size averaging accuracy. In Experiment 1, we tested participants' accuracy in comparing the mean size of two sets under various levels of object visual working memory load. Although the accuracy of average size judgments depended on the difference in mean size between the two sets, we found no effect of working memory load. In Experiment 2, we tested the same average size judgment while participants were under spatial visual working memory load, again finding no effect of load on averaging accuracy. Overall our results reveal that ensemble coding can proceed unimpeded and highly accurately under both object and spatial visual working memory load, providing further evidence that ensemble coding reflects a basic perceptual process distinct from that of individual object processing.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sparn, Bethany F; Ruth, Mark F; Krishnamurthy, Dheepak
Many have proposed that responsive load provided by distributed energy resources (DERs) and demand response (DR) are an option to provide flexibility to the grid and especially to distribution feeders. However, because responsive load involves a complex interplay between tariffs and DER and DR technologies, it is challenging to test and evaluate options without negatively impacting customers. This paper describes a hardware-in-the-loop (HIL) simulation system that has been developed to reduce the cost of evaluating the impact of advanced controllers (e.g., model predictive controllers) and technologies (e.g., responsive appliances). The HIL simulation system combines large-scale software simulation with a smallmore » set of representative building equipment hardware. It is used to perform HIL simulation of a distribution feeder and the loads on it under various tariff structures. In the reported HIL simulation, loads include many simulated air conditioners and one physical air conditioner. Independent model predictive controllers manage operations of all air conditioners under a time-of-use tariff. Results from this HIL simulation and a discussion of future development work of the system are presented.« less
Physical Insights, Steady Aerodynamic Effects, and a Design Tool for Low-Pressure Turbine Flutter
NASA Astrophysics Data System (ADS)
Waite, Joshua Joseph
The successful, efficient, and safe turbine design requires a thorough understanding of the underlying physical phenomena. This research investigates the physical understanding and parameters highly correlated to flutter, an aeroelastic instability prevalent among low pressure turbine (LPT) blades in both aircraft engines and power turbines. The modern way of determining whether a certain cascade of LPT blades is susceptible to flutter is through time-expensive computational fluid dynamics (CFD) codes. These codes converge to solution satisfying the Eulerian conservation equations subject to the boundary conditions of a nodal domain consisting fluid and solid wall particles. Most detailed CFD codes are accompanied by cryptic turbulence models, meticulous grid constructions, and elegant boundary condition enforcements all with one goal in mind: determine the sign (and therefore stability) of the aerodynamic damping. The main question being asked by the aeroelastician, "is it positive or negative?'' This type of thought-process eventually gives rise to a black-box effect, leaving physical understanding behind. Therefore, the first part of this research aims to understand and reveal the physics behind LPT flutter in addition to several related topics including acoustic resonance effects. A percentage of this initial numerical investigation is completed using an influence coefficient approach to study the variation the work-per-cycle contributions of neighboring cascade blades to a reference airfoil. The second part of this research introduces new discoveries regarding the relationship between steady aerodynamic loading and negative aerodynamic damping. Using validated CFD codes as computational wind tunnels, a multitude of low-pressure turbine flutter parameters, such as reduced frequency, mode shape, and interblade phase angle, will be scrutinized across various airfoil geometries and steady operating conditions to reach new design guidelines regarding the influence of steady aerodynamic loading and LPT flutter. Many pressing topics influencing LPT flutter including shocks, their nonlinearity, and three-dimensionality are also addressed along the way. The work is concluded by introducing a useful preliminary design tool that can estimate within seconds the entire aerodynamic damping versus nodal diameter curve for a given three-dimensional cascade.
Working conditions and health of the employees of public bus and trolleybus transport in Lithuania.
Obelenis, Vytautas; Gedgaudiene, Daiva; Vasilavicius, Paulius
2003-01-01
A questionnaire was used for investigation of 788 workers from three transport enterprises. The questionnaire was used for evaluation of occupational environment, lifestyle, psychosocial factors and self-evaluation of health. The most harmful occupational factors are unsatisfactory microclimatic conditions, diesel fuel, cooling oil, vibration, musculoskeletal load, and mental tension. Worker's lifestyle isn't healthy: 46% of them are smoking, 83% are drinking alcohol, 53% are physically inactive, 82% have bad nutrition regimen, 27% are everyday suffering from stressful situations. Main health impairments are musculoskeletal (46.2%), respiratory tract (22.2%), gastrointestinal (17.3%) and central nervous system (32.2%) diseases. Musculoskeletal disorders are statistically related to bad ergonomic work conditions, long workday hours, aged employees and long work experience of workers (p<0.05-0.002).
Study on power grid characteristics in summer based on Linear regression analysis
NASA Astrophysics Data System (ADS)
Tang, Jin-hui; Liu, You-fei; Liu, Juan; Liu, Qiang; Liu, Zhuan; Xu, Xi
2018-05-01
The correlation analysis of power load and temperature is the precondition and foundation for accurate load prediction, and a great deal of research has been made. This paper constructed the linear correlation model between temperature and power load, then the correlation of fault maintenance work orders with the power load is researched. Data details of Jiangxi province in 2017 summer such as temperature, power load, fault maintenance work orders were adopted in this paper to develop data analysis and mining. Linear regression models established in this paper will promote electricity load growth forecast, fault repair work order review, distribution network operation weakness analysis and other work to further deepen the refinement.
NASA Astrophysics Data System (ADS)
Pramod, P. S.; Shah, Ruchira; Jayakannan, Manickam
2015-04-01
The present work reports the development of pH and enzyme dual responsive polysaccharide vesicular nano-scaffolds for the administration of doxorubicin via physical loading and polymer-drug conjugation to breast cancer cells. Dextran was suitably modified with a renewable resource 3-pentadecyl phenol unit through imine and aliphatic ester chemical linkages that acted as pH and esterase enzyme stimuli, respectively. These dual responsive polysaccharide derivatives self-organized into 200 +/- 10 nm diameter nano-vesicles in water. The water soluble anticancer drug doxorubicin (DOX.HCl) was encapsulated in the hydrophilic pocket to produce core-loaded polysaccharide vesicles whereas chemical conjugation produced DOX anchored at the hydrophobic layer of the dextran nano-vesicles. In vitro studies revealed that about 70-80% of the drug was retained under circulatory conditions at pH = 7.4 and 37 °C. At a low pH of 6.0 to 5.0 and in the presence of esterase; both imine and ester linkages were cleaved instantaneously to release 100% of the loaded drugs. Cytotoxicity assays on Wild Type Mouse Embryonic Fibroblasts (WTMEFs) confirmed the non-toxicity of the newly developed dextran derivatives at up to 500 μg mL-1 in PBS. MTT assays on fibroblast cells revealed that DOX.HCl loaded nano-vesicles exhibited better killing abilities than DOX conjugated polymer nano-vesicles. Both DOX loaded and DOX conjugated nano-vesicles were found to show significant killing in breast cancer cells (MCF 7). Confocal microscopy images confirmed the uptake of DOX loaded (or conjugated) nano-vesicles by cells compared to free DOX. Thus, the newly developed pH and enzyme dual responsive polysaccharide vesicular assemblies are potential drug vectors for the administration of DOX in both loaded and chemically conjugated forms for the efficient killing of breast cancer cells.The present work reports the development of pH and enzyme dual responsive polysaccharide vesicular nano-scaffolds for the administration of doxorubicin via physical loading and polymer-drug conjugation to breast cancer cells. Dextran was suitably modified with a renewable resource 3-pentadecyl phenol unit through imine and aliphatic ester chemical linkages that acted as pH and esterase enzyme stimuli, respectively. These dual responsive polysaccharide derivatives self-organized into 200 +/- 10 nm diameter nano-vesicles in water. The water soluble anticancer drug doxorubicin (DOX.HCl) was encapsulated in the hydrophilic pocket to produce core-loaded polysaccharide vesicles whereas chemical conjugation produced DOX anchored at the hydrophobic layer of the dextran nano-vesicles. In vitro studies revealed that about 70-80% of the drug was retained under circulatory conditions at pH = 7.4 and 37 °C. At a low pH of 6.0 to 5.0 and in the presence of esterase; both imine and ester linkages were cleaved instantaneously to release 100% of the loaded drugs. Cytotoxicity assays on Wild Type Mouse Embryonic Fibroblasts (WTMEFs) confirmed the non-toxicity of the newly developed dextran derivatives at up to 500 μg mL-1 in PBS. MTT assays on fibroblast cells revealed that DOX.HCl loaded nano-vesicles exhibited better killing abilities than DOX conjugated polymer nano-vesicles. Both DOX loaded and DOX conjugated nano-vesicles were found to show significant killing in breast cancer cells (MCF 7). Confocal microscopy images confirmed the uptake of DOX loaded (or conjugated) nano-vesicles by cells compared to free DOX. Thus, the newly developed pH and enzyme dual responsive polysaccharide vesicular assemblies are potential drug vectors for the administration of DOX in both loaded and chemically conjugated forms for the efficient killing of breast cancer cells. Electronic supplementary information (ESI) available: 13C NMR of DEX-CHO, 2D NMR spectra of DEX-CHO, 1H NMR of DEX-IM, 1H NMR of DEX-IM-DOX conjugated, absorbance spectra of DEX-IM-DOX conjugated, DLS, FE-SEM and TEM image of DEX-CHO-5, emission spectra of pyrene and Nile red with DEX-IM-10, FE-SEM image of DEX-IM-DOX loaded, FE-SEM image of acid treated DEX-IM-5, absorbance spectra of DOX released, in vitro DOX release from drug loaded and conjugated vesicles in the presence of serum (FBS), DLS data depicting stability of DEX-IM vesicles in serum (FBS), 1HNMR, 13C NMR and HR-MS spectra of all intermediates are provided. See DOI: 10.1039/c5nr00799b
Ross, Jennifer A; Shipp, Eva M; Trueblood, Amber B; Bhattacharya, Amit
2016-08-01
To honor Tom Waters's work on emerging occupational health issues, we review the literature on physical along with chemical exposures and their impact on functional outcomes. Many occupations present the opportunity for exposure to multiple hazardous exposures, including both physical and chemical factors. However, little is known about how these different factors affect functional ability and injury. The goal of this review is to examine the relationships between these exposures, impairment of the neuromuscular and musculoskeletal systems, functional outcomes, and health problems with a focus on acute injury. Literature was identified using online databases, including PubMed, Ovid Medline, and Google Scholar. References from included articles were searched for additional relevant articles. This review documented the limited existing literature that discussed cognitive impairment and functional disorders via neurotoxicity for physical exposures (heat and repetitive loading) and chemical exposures (pesticides, volatile organic compounds [VOCs], and heavy metals). This review supports that workers are exposed to physical and chemical exposures that are associated with negative health effects, including functional impairment and injury. Innovation in exposure assessment with respect to quantifying the joint exposure to these different exposures is especially needed for developing risk assessment models and, ultimately, preventive measures. Along with physical exposures, chemical exposures need to be considered, alone and in combination, in assessing functional ability and occupationally related injuries. © 2016, Human Factors and Ergonomics Society.
Balogh, I; Ohlsson, K; Nordander, C; Björk, J; Hansson, G-Å
2016-03-01
We have evaluated the consequences of work organization on musculoskeletal health. Using a postal questionnaire, answered by 1600 female grocery store workers, their main work tasks were identified and four work groups were defined (cashier, picking, and delicatessen work, and a mixed group, who performed a mix of these tasks). The crude odds ratios (ORs) for neck/shoulder complaints were 1.5 (95% CI 1.0-2.2), 1.1 (0.7-1.5) and 1.6 (1.1-2.3), respectively, compared to mixed work. Adjusting for individual and psychosocial factors had no effect on these ORs. For elbows/hands, no significant differences were found. Technical measurements of the workload showed large differences between the work groups. Picking work was the most strenuous, while cashier work showed low loads. Quantitative measures of variation revealed for mixed work high between minutes variation and the highest between/within minutes variation. Combining work tasks with different physical exposure levels increases the variation and may reduce the risk of musculoskeletal complaints. Copyright © 2015 Elsevier Ltd and The Ergonomics Society. All rights reserved.
de Wind, Astrid; Scharn, Micky; Geuskens, Goedele A; van der Beek, Allard J; Boot, Cécile R L
2018-02-17
An increasing number of retirees continue to work beyond retirement despite being eligible to retire. As the prevalence of chronic disease increases with age, working beyond retirement may go along with having a chronic disease. Working beyond retirement may be different for retirees with and without chronic disease. We aim to investigate whether demographic, socioeconomic and work characteristics, health and social factors predict working beyond retirement, in workers with and without a chronic disease. Employees aged 56-64 years were selected from the Study on Transitions in Employment, Ability and Motivation (N = 1125). Questionnaire data on demographic and work characteristics, health, social factors, and working beyond retirement were linked to registry data from Statistics Netherlands on socioeconomic characteristics. Separate prediction models were built for retirees with and without chronic disease using multivariate logistic regression analyses. Workers without chronic disease were more likely to work beyond retirement compared to workers with chronic disease (27% vs 23%). In retirees with chronic disease, work and health factors predicted working beyond retirement, while in retirees without a chronic disease, work, health and social factors predicted working beyond retirement. In the final model for workers with chronic disease, healthcare work, better physical health, higher body height, lower physical load and no permanent contract were positively predictive of working beyond retirement. In the final model for workers without chronic disease, feeling full of life and being intensively physically active for > = 2 days per week were positively predictive of working beyond retirement; while manual labor, better recovery, and a partner who did not support working until the statutory retirement age, were negatively predictive of working beyond retirement. Work and health factors independently predicted working beyond retirement in workers with and without chronic disease, whereas social factors only did so among workers without chronic disease. Demographic and socioeconomic characteristics did not independently contribute to prediction of working beyond retirement in any group. As prediction of working beyond retirement was more difficult among workers with a chronic disease, future research is needed in this group.
Regular dog-walking improves physical capacity in elderly patients after myocardial infarction.
Ruzić, Alen; Miletić, Bojan; Ruzić, Tatjana; Persić, Viktor; Laskarin, Gordana
2011-09-01
Various positive effects of pet ownership on cardiovascular health are well known. The aim of this prospective and controlled longitudinal study was to determine the effects of everyday dog-walking on physical capacity in elderly patients during the first year after myocardial infarction. Regularly dog-walking for at least 15 minutes three times a day is related to significantly higher work load on the bicycle exercise test (72.5 +/- 10.75 versus 67.6 +/- 11.6 W p < 0.05) in the "dog-walking" group (N = 29, mean age 72.5 years) at 12 months compared to the control group (N = 30, mean age 71.7 years). Our results suggest that dogs may help to maintain continuous physical activity in elderly cardiovascular patients promoting their physical capacity. Further researches are needed to confirm this association as well to identify other possible influences of dog ownership on the cardiovascular health and on the outcome in patients after myocardial infarction.
Spatial working memory load affects counting but not subitizing in enumeration.
Shimomura, Tomonari; Kumada, Takatsune
2011-08-01
The present study investigated whether subitizing reflects capacity limitations associated with two types of working memory tasks. Under a dual-task situation, participants performed an enumeration task in conjunction with either a spatial (Experiment 1) or a nonspatial visual (Experiment 2) working memory task. Experiment 1 showed that spatial working memory load affected the slope of a counting function but did not affect subitizing performance or subitizing range. Experiment 2 showed that nonspatial visual working memory load affected neither enumeration efficiency nor subitizing range. Furthermore, in both spatial and nonspatial memory tasks, neither subitizing efficiency nor subitizing range was affected by amount of imposed memory load. In all the experiments, working memory load failed to influence slope, subitizing range, or overall reaction time. These findings suggest that subitizing is performed without either spatial or nonspatial working memory. A possible mechanism of subitizing with independent capacity of working memory is discussed.
Efficacy of a workplace osteoporosis prevention intervention: a cluster randomized trial.
Tan, Ai May; LaMontagne, Anthony D; English, Dallas R; Howard, Peter
2016-08-24
Osteoporosis is a debilitating disease. Adequate calcium consumption and physical activity are the two major modifiable risk factors. This paper describes the major outcomes and efficacy of a workplace-based targeted behaviour change intervention to improve the dietary and physical activity behaviours of working women in sedentary occupations in Singapore. A cluster-randomized design was used, comparing the efficacy of a tailored intervention to standard care. Workplaces were the units of randomization and intervention. Sixteen workplaces were recruited from a pool of 97, and randomly assigned to intervention and control arms (eight workplaces in each). Women meeting specified inclusion criteria were then recruited to participate. Workplaces in the intervention arm received three participatory workshops and organization-wide educational activities. Workplaces in the control/standard care arm received print resources. Outcome measures were calcium intake (milligrams/day) and physical activity level (duration: minutes/week), measured at baseline, 4 weeks and 6 months post intervention. Adjusted cluster-level analyses were conducted comparing changes in intervention versus control groups, following intention-to-treat principles and CONSORT guidelines. Workplaces in the intervention group reported a significantly greater increase in calcium intake and duration of load-bearing moderate to vigorous physical activity (MVPA) compared with the standard care control group. Four weeks after intervention, the difference in adjusted mean calcium intake was 343.2 mg/day (95 % CI = 337.4 to 349.0, p < .0005) and the difference in adjusted mean load-bearing MVPA was 55.6 min/week (95 % CI = 54.5 to 56.6, p < .0005). Six months post intervention, the mean differences attenuated slightly to 290.5 mg/day (95 % CI = 285.3 to 295.7, p < .0005) and 50.9 min/week (95 % CI =49.3 to 52.6, p < .0005) respectively. This workplace-based intervention substantially improved calcium intake and load-bearing moderate to vigorous physical activity 6 months after the intervention began. Australia New Zealand Clinical Trial Registry ACTRN12616000079448 . Registered 25 January 2016 (retrospectively registered).
Metal-loaded organic scintillators for neutrino physics
Buck, Christian; Yeh, Minfang
2016-08-03
Organic liquid scintillators are used in many neutrino physics experiments of the past and present. In particular for low energy neutrinos when realtime and energy information are required, liquid scintillators have several advantages compared to other technologies. In many cases the organic liquid needs to be loaded with metal to enhance the neutrino signal over background events. Several metal loaded scintillators of the past suffered from chemical and optical instabilities, limiting the performance of these neutrino detectors. Different ways of metal loading are described in the article with a focus on recent techniques providing metal loaded scintillators that can bemore » used under stable conditions for many years even in ton scale experiments. Lastly, we review applications of metal loaded scintillators in neutrino experiments and compare the performance as well as the prospects of different scintillator types.« less
Working memory load modulation of parieto-frontal connections: evidence from dynamic causal modeling
Ma, Liangsuo; Steinberg, Joel L.; Hasan, Khader M.; Narayana, Ponnada A.; Kramer, Larry A.; Moeller, F. Gerard
2011-01-01
Previous neuroimaging studies have shown that working memory load has marked effects on regional neural activation. However, the mechanism through which working memory load modulates brain connectivity is still unclear. In this study, this issue was addressed using dynamic causal modeling (DCM) based on functional magnetic resonance imaging (fMRI) data. Eighteen normal healthy subjects were scanned while they performed a working memory task with variable memory load, as parameterized by two levels of memory delay and three levels of digit load (number of digits presented in each visual stimulus). Eight regions of interest, i.e., bilateral middle frontal gyrus (MFG), anterior cingulate cortex (ACC), inferior frontal cortex (IFC), and posterior parietal cortex (PPC), were chosen for DCM analyses. Analysis of the behavioral data during the fMRI scan revealed that accuracy decreased as digit load increased. Bayesian inference on model structure indicated that a bilinear DCM in which memory delay was the driving input to bilateral PPC and in which digit load modulated several parieto-frontal connections was the optimal model. Analysis of model parameters showed that higher digit load enhanced connection from L PPC to L IFC, and lower digit load inhibited connection from R PPC to L ACC. These findings suggest that working memory load modulates brain connectivity in a parieto-frontal network, and may reflect altered neuronal processes, e.g., information processing or error monitoring, with the change in working memory load. PMID:21692148
Rotenberg, Lúcia; Portela, Luciana Fernandes; Banks, Bahby; Griep, Rosane Harter; Fischer, Frida Marina; Landsbergis, Paul
2008-09-01
The association between working hours and work ability was examined in a cross-sectional study of male (N=156) and female (N=1092) nurses in three public hospitals. Working hours were considered in terms of their professional and domestic hours per week and their combined impact; total work load. Logistic regression analysis showed a significant association between total work load and inadequate work ability index (WAI) for females only. Females reported a higher proportion of inadequate WAI, fewer professional work hours but longer domestic work hours. There were no significant differences in total work load by gender. The combination of professional and domestic work hours in females seemed to best explain their lower work ability. The findings suggest that investigations into female well-being need to consider their total work load. Our male sample may have lacked sufficient power to detect a relationship between working hours and work ability.
Field assessment of alternative bed-load transport estimators
Gaeuman, G.; Jacobson, R.B.
2007-01-01
Measurement of near-bed sediment velocities with acoustic Doppler current profilers (ADCPs) is an emerging approach for quantifying bed-load sediment fluxes in rivers. Previous investigations of the technique have relied on conventional physical bed-load sampling to provide reference transport information with which to validate the ADCP measurements. However, physical samples are subject to substantial errors, especially under field conditions in which surrogate methods are most needed. Comparisons between ADCP bed velocity measurements with bed-load transport rates estimated from bed-form migration rates in the lower Missouri River show a strong correlation between the two surrogate measures over a wide range of mild to moderately intense sediment transporting conditions. The correlation between the ADCP measurements and physical bed-load samples is comparatively poor, suggesting that physical bed-load sampling is ineffective for ground-truthing alternative techniques in large sand-bed rivers. Bed velocities measured in this study became more variable with increasing bed-form wavelength at higher shear stresses. Under these conditions, bed-form dimensions greatly exceed the region of the bed ensonified by the ADCP, and the magnitude of the acoustic measurements depends on instrument location with respect to bed-form crests and troughs. Alternative algorithms for estimating bed-load transport from paired longitudinal profiles of bed topography were evaluated. An algorithm based on the routing of local erosion and deposition volumes that eliminates the need to identify individual bed forms was found to give results similar to those of more conventional dune-tracking methods. This method is particularly useful in cases where complex bed-form morphology makes delineation of individual bed forms difficult. ?? 2007 ASCE.
Williams, Jessica A R; Arcaya, Mariana; Subramanian, S V
2017-11-01
The aim of this study was to evaluate relationships between work context and two health behaviors, healthy eating and leisure-time physical activity (LTPA), in U.S. adults. Using data from the 2010 National Health Interview Survey (NHIS) and Occupational Information Network (N = 14,863), we estimated a regression model to predict the marginal and joint probabilities of healthy eating and adhering to recommended exercise guidelines. Decision-making freedom was positively related to healthy eating and both behaviors jointly. Higher physical load was associated with a lower marginal probability of LTPA, healthy eating, and both behaviors jointly. Smoke and vapor exposures were negatively related to healthy eating and both behaviors. Chemical exposure was positively related to LTPA and both behaviors. Characteristics associated with marginal probabilities were not always predictive of joint outcomes. On the basis of nationwide occupation-specific evidence, workplace characteristics are important for healthy eating and LTPA.
Field quantification of physical exposures of police officers in vehicle operation.
McKinnon, Colin D; Callaghan, Jack P; Dickerson, Clark R
2011-01-01
Mobile police officers perform many of their daily duties in their vehicles. Combined workspace inflexibility and prolonged driving create potential musculoskeletal injury risks. Limited research exists that quantitatively describes postural and load exposures associated with mobile police work. The purpose of this study was to characterize officer activity during a typical workday and identify opportunities for ergonomic intervention. Digital video of traffic officers (N = 10) was used to classify postures according to work activity. Cumulative time in 10 activities was calculated, and a time-history of driver activity documented. Most (55.5 ± 13.4%) time was out of the vehicle, and 22.3 ± 10.5% was spent in single-arm driving. On paper documentation and mobile data terminal use were identified as in-car activities that may benefit from targeted interventions. The primary contribution of this study is characterization of daily mobile police activity and the identification of possible intervention strategies to mitigate physical exposure levels.
Factors Associated With Work Ability in Patients Undergoing Surgery for Cervical Radiculopathy.
Ng, Eunice; Johnston, Venerina; Wibault, Johanna; Löfgren, Håkan; Dedering, Åsa; Öberg, Birgitta; Zsigmond, Peter; Peolsson, Anneli
2015-08-15
Cross-sectional study. To investigate the factors associated with work ability in patients undergoing surgery for cervical radiculopathy. Surgery is a common treatment of cervical radiculopathy in people of working age. However, few studies have investigated the impact on the work ability of these patients. Patients undergoing surgery for cervical radiculopathy (n = 201) were recruited from spine centers in Sweden to complete a battery of questionnaires and physical measures the day before surgery. The associations between various individual, psychological, and work-related factors and self-reported work ability were investigated by Spearman rank correlation coefficient, multivariate linear regression, and forward stepwise regression analyses. Factors that were significant (P < 0.05) in each statistical analysis were entered into the successive analysis to reveal the factors most related to work ability. Work ability was assessed using the Work Ability Index. The mean Work Ability Index score was 28 (SD, 9.0). The forward stepwise regression analysis revealed 6 factors significantly associated with work ability, which explained 62% of the variance in the Work Ability Index. Factors highly correlated with greater work ability included greater self-efficacy in performing self-cares, lower physical load on the neck at work, greater self-reported chance of being able to work in 6 months' time, greater use of active coping strategies, lower frequency of hand weakness, and higher health-related quality of life. Psychological, work-related and individual factors were significantly associated with work ability in patients undergoing surgery for cervical radiculopathy. High self-efficacy was most associated with greater work ability. Consideration of these factors by surgeons preoperatively may provide optimal return to work outcomes after surgery. 3.
Evaluation of Mid-Size Male Hybrid III Models for use in Spaceflight Occupant Protection Analysis
NASA Technical Reports Server (NTRS)
Putnam, J.; Somers, J.; Wells, J.; Newby, N.; Currie-Gregg, N.; Lawrence, C.
2016-01-01
Introduction: In an effort to improve occupant safety during dynamic phases of spaceflight, the National Aeronautics and Space Administration (NASA) has worked to develop occupant protection standards for future crewed spacecraft. One key aspect of these standards is the identification of injury mechanisms through anthropometric test devices (ATDs). Within this analysis, both physical and computational ATD evaluations are required to reasonably encompass the vast range of loading conditions any spaceflight crew may encounter. In this study the accuracy of publically available mid-size male HIII ATD finite element (FE) models are evaluated within applicable loading conditions against extensive sled testing performed on their physical counterparts. Methods: A series of sled tests were performed at the Wright Patterson Air force Base (WPAFB) employing variations of magnitude, duration, and impact direction to encompass the dynamic loading range for expected spaceflight. FE simulations were developed to the specifications of the test setup and driven using measured acceleration profiles. Both fast and detailed FE models of the mid-size male HIII were ran to quantify differences in their accuracy and thus assess the applicability of each within this field. Results: Preliminary results identify the dependence of model accuracy on loading direction, magnitude, and rate. Additionally the accuracy of individual response metrics are shown to vary across each model within evaluated test conditions. Causes for model inaccuracy are identified based on the observed relationships. Discussion: Computational modeling provides an essential component to ATD injury metric evaluation used to ensure the safety of future spaceflight occupants. The assessment of current ATD models lays the groundwork for how these models can be used appropriately in the future. Identification of limitations and possible paths for improvement aid in the development of these effective analysis tools.
Evaluation of Mid-Size Male Hybrid III Models for use in Spaceflight Occupant Protection Analysis
NASA Technical Reports Server (NTRS)
Putnam, Jacob B.; Sommers, Jeffrey T.; Wells, Jessica A.; Newby, Nathaniel J.; Currie-Gregg, Nancy J.; Lawrence, Chuck
2016-01-01
In an effort to improve occupant safety during dynamic phases of spaceflight, the National Aeronautics and Space Administration (NASA) has worked to develop occupant protection standards for future crewed spacecraft. One key aspect of these standards is the identification of injury mechanisms through anthropometric test devices (ATDs). Within this analysis, both physical and computational ATD evaluations are required to reasonably encompass the vast range of loading conditions any spaceflight crew may encounter. In this study the accuracy of publically available mid-size male HIII ATD finite element (FE) models are evaluated within applicable loading conditions against extensive sled testing performed on their physical counterparts. Methods: A series of sled tests were performed at the Wright Patterson Air force Base (WPAFB) employing variations of magnitude, duration, and impact direction to encompass the dynamic loading range for expected spaceflight. FE simulations were developed to the specifications of the test setup and driven using measured acceleration profiles. Both fast and detailed FE models of the mid-size male HIII were ran to quantify differences in their accuracy and thus assess the applicability of each within this field. Results: Preliminary results identify the dependence of model accuracy on loading direction, magnitude, and rate. Additionally the accuracy of individual response metrics are shown to vary across each model within evaluated test conditions. Causes for model inaccuracy are identified based on the observed relationships. Discussion: Computational modeling provides an essential component to ATD injury metric evaluation used to ensure the safety of future spaceflight occupants. The assessment of current ATD models lays the groundwork for how these models can be used appropriately in the future. Identification of limitations and possible paths for improvement aid in the development of these effective analysis tools.
Mélan, Claudine; Cascino, Nadine
2014-01-01
The present contribution presents two field studies combining tools and methods from cognitive psychology and from occupational psychology in order to perform a thorough investigation of workload in employees. Cognitive load theory proposes to distinguish different load categories of working memory, in a context of instruction. Intrinsic load is inherent to the task, extraneous load refers to components of a learning environment that may be modified to reduce total load, and germane load enables schemas construction and thus efficient learning. We showed previously that this theoretical framework may be successfully extended to working memory tasks in non-instructional designs. Other theoretical models, issued from the field of occupational psychology, account for an individual’s perception of work demands or requirements in the context of different psychosocial features of the (work) environment. Combining these approaches is difficult as workload assessment by job-perception questionnaires explore an individual’s overall job-perception over a large time-period, whereas cognitive load investigations in working memory tasks are typically performed within short time-periods. We proposed an original methodology enabling investigation of workload and load factors in a comparable time-frame. We report two field studies investigating workload on different shift-phases and between work-shifts, with two custom-made tools. The first one enabled workload assessment by manipulating intrinsic load (task difficulty) and extraneous load (time pressure) in a working-memory task. The second tool was a questionnaire based on the theoretical concepts of work-demands, control, and psychosocial support. Two additional dimensions suspected to contribute to job-perception, i.e., work–family conflicts and availability of human and technical resources were also explored. Results of workload assessments were discussed in light of operators’ alertness and job-performance. PMID:25232346
Sarnyai, Zoltán; Berger, Maximus; Jawan, Isabella
2016-02-01
A considerable gap exists in health and social emotional well-being between Indigenous people and non-Indigenous Australians. Recent research in stress neurobiology highlights biological pathways that link early adversity and traumas as well as life stresses to ill health. We argue that the neurobiological stress response and its maladaptive changes, termed allostatic load, provide a useful framework to understand how adversity leads to physical and mental illness in Indigenous people. In this paper we review the biology of allostatic load and make links between stress-induced systemic hormonal, metabolic and immunological changes and physical and mental illnesses. Exposure to chronic stress throughout life results in an increased allostatic load that may contribute to a number of metabolic, cardiovascular and mental disorders that shorten life expectancy in Indigenous Australians. © The Royal Australian and New Zealand College of Psychiatrists 2015.
VO2 kinetics of constant-load exercise following bed-rest-induced deconditioning
NASA Technical Reports Server (NTRS)
Convertino, V. A.; Goldwater, D. J.; Sandler, H.
1984-01-01
Previous studies have shown that the oxygen uptake kinetics during exercise and recovery may be changed by alterations in work intensity, prior exercise, muscle group involvement, ambient conditions, posture, disease state, and level of physical conditioning. However, the effects of detraining on oxygen uptake kinetics have not been determined. The present investigation has the objective to determine the effects of deconditioning following seven days of continuous head-down bed rest on changes in steady-state oxygen uptake, O2 deficit, and recovery oxygen uptake during the performance of constant-load exercise. The obtained results may provide support for previous proposals that submaximal oxygen uptake was significantly reduced following bed rest. The major finding was that bed-rest deconditioning resulted in a reduction of total O2 transport/utilization capacity during the transient phase of upright but not supine exercise.
Comparisons Between Stability Prediction and Measurements for the Reusable Solid Rocket Motor
NASA Technical Reports Server (NTRS)
Fischbach, Sean R.; Kenny, R. Jeremy
2010-01-01
The Space Transportation System has used the solid rocket boosters for lift-off and ascent propulsion over the history of the program. Part of the structural loads assessment of the assembled vehicle is the contribution due to solid rocket booster thrust oscillations. These thrust oscillations are a consequence of internal motor pressure oscillations active during operation. Understanding of these pressure oscillations is key to predicting the subsequent thrust oscillations and vehicle loading. The pressure oscillation characteristics of the Reusable Solid Rocket Motor (RSRM) design are reviewed in this work. Dynamic pressure data from the static test and flight history are shown, with emphasis on amplitude, frequency, and timing of the oscillations. Physical mechanisms that cause these oscillations are described by comparing data observations to predictions made by the Solid Stability Prediction (SSP) code.
NASA Technical Reports Server (NTRS)
Grimes, C. A.; Kouzoudis, D.
2000-01-01
Free-standing magnetoelastic thick-film sensors have a characteristic resonant frequency that can be determined by monitoring the magnetic flux emitted from the sensor in response to a time varying magnetic field. This property allows the sensors to be monitored remotely without the use of direct physical connections, such as wires, enabling measurement of environmental parameters from within sealed, opaque containers. In this work, we report on application of magnetoelastic sensors to measurement of atmospheric pressure, fluid-flow velocity, temperature, and mass load. Mass loading effects are demonstrated by fabrication of a remote query humidity sensor, made by coating the magnetoelastic thick film with a thin layer of solgel deposited Al2O3 that reversibly changes mass in response to humidity. c2000 Elsevier Science S.A. All rights reserved.
Autonomous Cryogenics Loading Operations Simulation Software: Knowledgebase Autonomous Test Engineer
NASA Technical Reports Server (NTRS)
Wehner, Walter S., Jr.
2013-01-01
Working on the ACLO (Autonomous Cryogenics Loading Operations) project I have had the opportunity to add functionality to the physics simulation software known as KATE (Knowledgebase Autonomous Test Engineer), create a new application allowing WYSIWYG (what-you-see-is-what-you-get) creation of KATE schematic files and begin a preliminary design and implementation of a new subsystem that will provide vision services on the IHM (Integrated Health Management) bus. The functionality I added to KATE over the past few months includes a dynamic visual representation of the fluid height in a pipe based on number of gallons of fluid in the pipe and implementing the IHM bus connection within KATE. I also fixed a broken feature in the system called the Browser Display, implemented many bug fixes and made changes to the GUI (Graphical User Interface).
Dimensional stability of pineapple leaf fibre reinforced phenolic composites
NASA Astrophysics Data System (ADS)
Asim, M.; Jawaid, M.; Abdan, K.; Ishak, M. R.
2017-12-01
In this research, pineapple leaves fibre (PALF)/phenolic resin (PF) composites were fabricated by hand lay-up method. The aim of this work is to investigate the physical properties (water absorption and thickness swelling) of PALF reinforced phenolic resin composites. Long-term water absorption (WA) and thickness swelling (TS) behaviours of the PALF/PF composites were investigated at several water immersion times. The effects of different fibre loading on WA and TS of PALF/PF composites were also analyzed. Obtained results indicated that the WA and TS of PALF/PF composites vary with fibres content and water immersion time before reaching to equilibrium. WA and TS of PALF/PF composites were increased by increasing fibre loading. Results obtained in this study will be used for further study on hybridization of PALF and Kenaf fibre based phenolic composites.
Effect of local void morphology on the reaction initiation mechanism in the case of pressed HMX
NASA Astrophysics Data System (ADS)
Roy, Sidhartha; Rai, Nirmal; Udaykumar, H. S.
2017-06-01
The microstructural characteristics of pressed HMX has a significant effect on its sensitivity under shock loading. The microstructure of pressed HMX contains voids of various orientation and aspect ratio. Subject to shock loading, these voids can collapse forming hotspots and initiate chemical reaction. This work shows how the ignition and growth of chemical reaction is dependent on the local microstructural features of the voids. Morphological quantities like size, aspect ratio and orientations are extracted from the real microstructural images of Class III and Class V pressed HMX. These morphological quantities are correlated with the ignition and growth rates of the chemical reaction. The dependency of the sensitivity of a given HMX sample on the local morphological features shows that these local features can create a mocroscale physical response.
Comparison of point-source pollutant loadings to soil and groundwater for 72 chemical substances.
Yu, Soonyoung; Hwang, Sang-Il; Yun, Seong-Taek; Chae, Gitak; Lee, Dongsu; Kim, Ki-Eun
2017-11-01
Fate and transport of 72 chemicals in soil and groundwater were assessed by using a multiphase compositional model (CompFlow Bio) because some of the chemicals are non-aqueous phase liquids or solids in the original form. One metric ton of chemicals were assumed to leak in a stylized facility. Scenarios of both surface spills and subsurface leaks were considered. Simulation results showed that the fate and transport of chemicals above the water table affected the fate and transport of chemicals below the water table, and vice versa. Surface spill scenarios caused much less concentrations than subsurface leak scenarios because leaching amounts into the subsurface environment were small (at most 6% of the 1 t spill for methylamine). Then, simulation results were applied to assess point-source pollutant loadings to soil and groundwater above and below the water table, respectively, by multiplying concentrations, impact areas, and durations. These three components correspond to the intensity of contamination, mobility, and persistency in the assessment of pollutant loading, respectively. Assessment results showed that the pollutant loadings in soil and groundwater were linearly related (r 2 = 0.64). The pollutant loadings were negatively related with zero-order and first-order decay rates in both soil (r = - 0.5 and - 0.6, respectively) and groundwater (- 1.0 and - 0.8, respectively). In addition, this study scientifically defended that the soil partitioning coefficient (K d ) significantly affected the pollutant loadings in soil (r = 0.6) and the maximum masses in groundwater (r = - 0.9). However, K d was not a representative factor for chemical transportability unlike the expectation in chemical ranking systems of soil and groundwater pollutants. The pollutant loadings estimated using a physics-based hydrogeological model provided a more rational ranking for exposure assessment, compared to the summation of persistency and transportability scores in the chemical ranking systems. In the surface spill scenario, the pollutant loadings were zeros for all chemicals, except methylamine to soil whose pollutant loading was smaller than that in the subsurface leak scenario by 4 orders of magnitude. The maximum mass and the average mass multiplied by duration in soil greatly depended on leaching fluxes (r = 1.0 and 0.9, respectively), while the effect of leaching fluxes diminished below the water table. The contribution of this work is that a physics-based numerical model was used to quantitatively compare the subsurface pollutant loading in a chemical accident for 72 chemical substances, which can scientifically defend a simpler and more qualitative assessment of pollutant loadings. Besides, this study assessed pollutant loadings to soil (unsaturated zone) and groundwater (saturated zone) all together and discussed their interactions.
Weight and See: Loading Working Memory Improves Incidental Identification of Irrelevant Faces
Carmel, David; Fairnie, Jake; Lavie, Nilli
2012-01-01
Are task-irrelevant stimuli processed to a level enabling individual identification? This question is central both for perceptual processing models and for applied settings (e.g., eye-witness testimony). Lavie’s load theory proposes that working memory actively maintains attentional prioritization of relevant over irrelevant information. Loading working memory thus impairs attentional prioritization, leading to increased processing of task-irrelevant stimuli. Previous research has shown that increased working memory load leads to greater interference effects from response-competing distractors. Here we test the novel prediction that increased processing of irrelevant stimuli under high working memory load should lead to a greater likelihood of incidental identification of entirely irrelevant stimuli. To test this, we asked participants to perform a word-categorization task while ignoring task-irrelevant images. The categorization task was performed during the retention interval of a working memory task with either low or high load (defined by memory set size). Following the final experimental trial, a surprise question assessed incidental identification of the irrelevant image. Loading working memory was found to improve identification of task-irrelevant faces, but not of building stimuli (shown in a separate experiment to be less distracting). These findings suggest that working memory plays a critical role in determining whether distracting stimuli will be subsequently identified. PMID:22912623
Wakaskar, Rajesh R; Bathena, Sai Praneeth R; Tallapaka, Shailendra B; Ambardekar, Vishakha V; Gautam, Nagsen; Thakare, Rhishikesh; Simet, Samantha M; Curran, Stephen M; Singh, Rakesh K; Dong, Yuxiang; Vetro, Joseph A
2015-03-01
Determine the feasibility and potential benefit of peripherally cross-linking the shell of core-shell polymer micelles on the premature release of physically loaded hydrophobic drug in whole blood and subsequent potency against solid tumors. Individual Pluronic F127 polymer micelles (F127 PM) peripherally cross-linked with ethylenediamine at 76% of total PEO blocks (X-F127 PM) were physically loaded with combretastatin A4 (CA4) by the solid dispersion method and compared to CA4 physically loaded in uncross-linked F127 PM, CA4 in DMSO in vitro, or water-soluble CA4 phosphate (CA4P) in vivo. X-F127 PM had similar CA4 loading and aqueous solubility as F127 PM up to 10 mg CA4 / mL at 22.9 wt% and did not aggregate in PBS or 90% (v/v) human serum at 37°C for at least 24 h. In contrast, X-F127 PM decreased the unbound fraction of CA4 in whole blood (fu) and increased the mean plasma residence time and subsequent potency of CA4 against the vascular function and growth of primary murine 4T1 breast tumors over CA4 in F127 PM and water-soluble CA4P after IV administration. Given that decreasing the fu is an indication of decreased drug release, peripherally cross-linking the shell of core-shell polymer micelles may be a simple approach to decrease premature release of physically loaded hydrophobic drug in the blood and increase subsequent potency in solid tumors.
Curvilinear relationship between phonological working memory load and social-emotional modulation
Mano, Quintino R.; Brown, Gregory G.; Bolden, Khalima; Aupperle, Robin; Sullivan, Sarah; Paulus, Martin P.; Stein, Murray B.
2015-01-01
Accumulating evidence suggests that working memory load is an important factor for the interplay between cognitive and facial-affective processing. However, it is unclear how distraction caused by perception of faces interacts with load-related performance. We developed a modified version of the delayed match-to-sample task wherein task-irrelevant facial distracters were presented early in the rehearsal of pseudoword memoranda that varied incrementally in load size (1-syllable, 2-syllables, or 3-syllables). Facial distracters displayed happy, sad, or neutral expressions in Experiment 1 (N=60) and happy, fearful, or neutral expressions in Experiment 2 (N=29). Facial distracters significantly disrupted task performance in the intermediate load condition (2-syllable) but not in the low or high load conditions (1- and 3-syllables, respectively), an interaction replicated and generalised in Experiment 2. All facial distracters disrupted working memory in the intermediate load condition irrespective of valence, suggesting a primary and general effect of distraction caused by faces. However, sad and fearful faces tended to be less disruptive than happy faces, suggesting a secondary and specific valence effect. Working memory appears to be most vulnerable to social-emotional information at intermediate loads. At low loads, spare capacity is capable of accommodating the combinatorial load (1-syllable plus facial distracter), whereas high loads maximised capacity and deprived facial stimuli from occupying working memory slots to cause disruption. PMID:22928750
Mechanical Model for Dynamic Behavior of Concrete Under Impact Loading
NASA Astrophysics Data System (ADS)
Sun, Yuanxiang
Concrete is a geo-material which is used substantively in the civil building and military safeguard. One coupled model of damage and plasticity to describe the complex behavior of concrete subjected to impact loading is proposed in this research work. The concrete is assumed as homogeneous continuum with pre-existing micro-cracks and micro-voids. Damage to concrete is caused due to micro-crack nucleation, growth and coalescence, and defined as the probability of fracture at a given crack density. It induces a decrease of strength and stiffness of concrete. Compaction of concrete is physically a collapse of the material voids. It produces the plastic strain in the concrete and, at the same time, an increase of the bulk modulus. In terms of crack growth model, micro-cracks are activated, and begin to propagate gradually. When crack density reaches a critical value, concrete takes place the smashing destroy. The model parameters for mortar are determined using plate impact experiment with uni-axial strain state. Comparison with the test results shows that the proposed model can give consistent prediction of the impact behavior of concrete. The proposed model may be used to design and analysis of concrete structures under impact and shock loading. This work is supported by State Key Laboratory of Explosion science and Technology, Beijing Institute of Technology (YBKT14-02).
Marital satisfaction, recovery from work, and diurnal cortisol among men and women.
Saxbe, Darby E; Repetti, Rena L; Nishina, Adrienne
2008-01-01
Multilevel modeling was used to model relationships between salivary cortisol, daily diary ratings of work experiences, and Marital Adjustment Test scores (Locke & Wallace, 1959), in a sample of 60 adults who sampled saliva 4 times per day over 3 days. Among women but not men, marital satisfaction was significantly associated with a stronger basal cortisol cycle, with higher morning values and a steeper decline across the day. For women but not men, marital satisfaction moderated the within-subjects association between afternoon and evening cortisol level, such that marital quality appeared to bolster women's physiological recovery from work. For both men and women, evening cortisol was lower than usual on higher-workload days, and marital satisfaction augmented this association among women. Men showed higher evening cortisol after more distressing social experiences at work, an association that was strongest among men with higher marital satisfaction. This work has implications for the study of physiological recovery from work, and also suggests a pathway by which marital satisfaction influences allostatic load and physical health.
Choudhari, Shyamal P.; Chen, Xiaotong; Kim, Jae Hyun; van Roosmalen, Maarten L.; Greenwood, Jamie C.; Joshi, Sangeeta B.; Picking, William D.; Leenhouts, Kees; Middaugh, C. Russell; Picking, Wendy L.
2014-01-01
Bacterium-like particles (BLPs), derived from Lactococcus lactis, offer a self-adjuvanting delivery vehicle for subunit protein vaccines. Proteins can be specifically loaded onto the BLPs via a peptidoglycan anchoring domain (PA). In this study, the tip proteins IpaD, SipD and LcrV belonging to type three secretion systems of Shigella flexneri, Salmonella enterica and Yersinia enterocolitica, respectively, were fused to the PA and loaded onto the BLPs. Herein, we biophysically characterized these nine samples and condensed the spectroscopic results into three-index empirical phase diagrams (EPDs). The EPDs show distinctions between the IpaD/SipD and LcrV subfamilies of tip proteins, based on their physical stability, even upon addition of the PA. Upon attachment to the BLPs, the BLPs become defining moiety in the spectroscopic measurements, leaving the tip proteins to have a subtle yet modulating effect on the structural integrity of the tip proteins-BLPs binding. In summary, this work provides a comprehensive view of physical stability of the tip proteins and tip protein-BLPs and serves as a baseline for screening of excipients to increase the stability of the tip protein-BLPs for future vaccine formulation. PMID:24916512
Measuring spatial variability in soil characteristics
Hoskinson, Reed L.; Svoboda, John M.; Sawyer, J. Wayne; Hess, John R.; Hess, J. Richard
2002-01-01
The present invention provides systems and methods for measuring a load force associated with pulling a farm implement through soil that is used to generate a spatially variable map that represents the spatial variability of the physical characteristics of the soil. An instrumented hitch pin configured to measure a load force is provided that measures the load force generated by a farm implement when the farm implement is connected with a tractor and pulled through or across soil. Each time a load force is measured, a global positioning system identifies the location of the measurement. This data is stored and analyzed to generate a spatially variable map of the soil. This map is representative of the physical characteristics of the soil, which are inferred from the magnitude of the load force.
DOE Office of Scientific and Technical Information (OSTI.GOV)
J. S. Schroeder; R. W. Youngblood
The Risk-Informed Safety Margin Characterization (RISMC) pathway of the Light Water Reactor Sustainability Program is developing simulation-based methods and tools for analyzing safety margin from a modern perspective. [1] There are multiple definitions of 'margin.' One class of definitions defines margin in terms of the distance between a point estimate of a given performance parameter (such as peak clad temperature), and a point-value acceptance criterion defined for that parameter (such as 2200 F). The present perspective on margin is that it relates to the probability of failure, and not just the distance between a nominal operating point and a criterion.more » In this work, margin is characterized through a probabilistic analysis of the 'loads' imposed on systems, structures, and components, and their 'capacity' to resist those loads without failing. Given the probabilistic load and capacity spectra, one can assess the probability that load exceeds capacity, leading to component failure. Within the project, we refer to a plot of these probabilistic spectra as 'the logo.' Refer to Figure 1 for a notional illustration. The implications of referring to 'the logo' are (1) RISMC is focused on being able to analyze loads and spectra probabilistically, and (2) calling it 'the logo' tacitly acknowledges that it is a highly simplified picture: meaningful analysis of a given component failure mode may require development of probabilistic spectra for multiple physical parameters, and in many practical cases, 'load' and 'capacity' will not vary independently.« less
Fouad, H
2011-05-01
In previous work by Fouad (Medical Engineering and Physics 2010 [23]), 3D finite element (FE) models for fractured bones with function-graded (FG) bone-plates and traditional bone-plates made of stainless steel (SS) and titanium (Ti) alloy were examined under compressive loading conditions using the ABAQUS Code. In this study, the effects of the presence of the torsional load in addition to the compressive load on the predicted stresses of the fracture fixation bone-plate system are examined at different healing stages. The effects on the stress on the fracture site when using contacted and non-contacted bone-plate systems are also studied. The FE modelling results indicate that the torsional load has significant effects on the resultant stress on the fracture fixation bone-plate system, which should be taken into consideration during the design and the analysis. The results also show that the stress shielding at the fracture site decreases significantly when using FG bone-plates compared to Ti alloy or SS bone-plates. The presence of a gap between the bone and the plate results in a remarkable reduction in bone stress shielding at the fracture site. Therefore, the significant effects of using an FG bone-plate with a gap and the presence of torsional load on the resultant stress on the fracture fixation bone-plate system should be taken into consideration. Copyright © 2010 IPEM. Published by Elsevier Ltd. All rights reserved.
Attar, Nada; Schneps, Matthew H; Pomplun, Marc
2016-10-01
An observer's pupil dilates and constricts in response to variables such as ambient and focal luminance, cognitive effort, the emotional stimulus content, and working memory load. The pupil's memory load response is of particular interest, as it might be used for estimating observers' memory load while they are performing a complex task, without adding an interruptive and confounding memory test to the protocol. One important task in which working memory's involvement is still being debated is visual search, and indeed a previous experiment by Porter, Troscianko, and Gilchrist (Quarterly Journal of Experimental Psychology, 60, 211-229, 2007) analyzed observers' pupil sizes during search to study this issue. These authors found that pupil size increased over the course of the search, and they attributed this finding to accumulating working memory load. However, since the pupil response is slow and does not depend on memory load alone, this conclusion is rather speculative. In the present study, we estimated working memory load in visual search during the presentation of intermittent fixation screens, thought to induce a low, stable level of arousal and cognitive effort. Using standard visual search and control tasks, we showed that this paradigm reduces the influence of non-memory-related factors on pupil size. Furthermore, we found an early increase in working memory load to be associated with more efficient search, indicating a significant role of working memory in the search process.
NASA Astrophysics Data System (ADS)
Zhu, Na
This thesis presents an overview of the previous research work on dynamic characteristics and energy performance of buildings due to the integration of PCMs. The research work on dynamic characteristics and energy performance of buildings using PCMs both with and without air-conditioning is reviewed. Since the particular interest in using PCMs for free cooling and peak load shifting, specific research efforts on both subjects are reviewed separately. A simplified physical dynamic model of building structures integrated with SSPCM (shaped-stabilized phase change material) is developed and validated in this study. The simplified physical model represents the wall by 3 resistances and 2 capacitances and the PCM layer by 4 resistances and 2 capacitances respectively while the key issue is the parameter identification of the model. This thesis also presents the studies on the thermodynamic characteristics of buildings enhanced by PCM and on the investigation of the impacts of PCM on the building cooling load and peak cooling demand at different climates and seasons as well as the optimal operation and control strategies to reduce the energy consumption and energy cost by reducing the air-conditioning energy consumption and peak load. An office building floor with typical variable air volume (VAV) air-conditioning system is used and simulated as the reference building in the comparison study. The envelopes of the studied building are further enhanced by integrating the PCM layers. The building system is tested in two selected cities of typical climates in China including Hong Kong and Beijing. The cold charge and discharge processes, the operation and control strategies of night ventilation and the air temperature set-point reset strategy for minimizing the energy consumption and electricity cost are studied. This thesis presents the simulation test platform, the test results on the cold storage and discharge processes, the air-conditioning energy consumption and demand reduction potentials in typical air-conditioning seasons in typical China cites as well as the impacts of operation and control strategies.
Quality of life in Essential Tremor Questionnaire (QUEST): development and initial validation.
Tröster, Alexander I; Pahwa, Rajesh; Fields, Julie A; Tanner, Caroline M; Lyons, Kelly E
2005-09-01
Essential tremor (ET) can diminish functioning and quality of life (QOL) but generic QOL measures may be relatively insensitive to ET and its therapies. We sought to develop an ET-specific measure that might be more sensitive, acceptable to patients, relatively brief, and easily used. A sample of 200 patients (average age 70 years, range 30-91; average disease duration 15 years) rated the extent to which tremor impacts a function or state, tremor severity in various body parts, perceived health, and overall QOL. Responses to this initial questionnaire were subjected to principal components analysis (PCA). Inspection of factor coordinates, Eigenvalues, variance accounted for, and correlation matrices were used to select items for confirmatory PCA. Final scale reliability was assessed using Cronbach's alpha. Validity was evaluated by correlations between QOL scales and self-rated tremor severity. PCA of 65 initial items yielded 11 factors accounting for 71% of variance. Six factors were discarded. Two items were eliminated for not loading on a factor and 33 for perceived redundancy. Confirmatory PCA of the retained 30 items yielded an almost identical factor structure (six factors, 70% of variance accounted for, and similar item loadings). Because two factors had very few items loading on them, these two factors were combined into one scale. The final measure has five scales: Physical, Psychosocial, Communication, Hobbies/Leisure, and Work/Finance. Reliability was excellent for the whole instrument and four scales (> or =0.89), and good for the Work/Finance scale (0.79). Severity of voice and head tremor were the best correlates of Communication (0.70 and 0.35), while the Physical scale was related to right and left upper extremity tremor (0.59 and 0.56). Scales correlated more highly with patients' rating of their overall QOL than their health perception. A brief, 30-item, ET-specific QOL scale with excellent reliability was developed. Preliminary validity data are encouraging. The Quality of Life in Essential Tremor Questionnaire (QUEST) promises to facilitate QOL measurement in ET.
Ergonomics/Human factors needs of an ageing workforce in the manufacturing sector.
W Stedmon, Alex; Howells, Hannah; R Wilson, John; Dianat, Iman
2012-01-01
As the effects of demographic transition are realised around the world, many in-dustrial societies are facing the effects of a baby boom generation, increased life expectancies, decreased birth rates and recent changes to retirement legislation with the result that older work¬ers are set to comprise a greater proportion of the labour force. This paper reviews the evidence for the physical and cognitive factors that characterise an ageing workforce in manufacturing. From an ergonomics and human factors (E/HF) pers¬pective, characteristics of manufacturing tasks and the effects of ageing provide an insight into how the industry will have to adapt to support the user needs of the older worker in the future. The approach taken is drawn from Ilmarinen's framework of age, experience, and work performance, from which specific E/HF issues are explored. There would appear to potential to support physical decline in older workers within manufacturing jobs through increased mechanisation and automation; however, those factors associated with cognitive human factors are less clear. Increased mechanisation and automation can place greater loads and demands on the older worker where cognitive decline is more subtle and varied between workers. Using historical and contemporary findings and the relationship between age, experience, and work performance is redrawn to include both cognitive skills and physical attributes to provide recommendations for future job design and worker needs.
Ergonomics/Human Factors Needs of an Ageing Workforce in the Manufacturing Sector
W. Stedmon, Alex; Howells, Hannah; R. Wilson, John; Dianat, Iman
2012-01-01
Background: As the effects of demographic transition are realised around the world, many in-dustrial societies are facing the effects of a baby boom generation, increased life expectancies, decreased birth rates and recent changes to retirement legislation with the result that older work¬ers are set to comprise a greater proportion of the labour force. Methods: This paper reviews the evidence for the physical and cognitive factors that characterise an ageing workforce in manufacturing. From an ergonomics and human factors (E/HF) pers¬pective, characteristics of manufacturing tasks and the effects of ageing provide an insight into how the industry will have to adapt to support the user needs of the older worker in the future. The approach taken is drawn from Ilmarinen’s framework of age, experience, and work performance, from which specific E/HF issues are explored. Results: There would appear to potential to support physical decline in older workers within manufacturing jobs through increased mechanisation and automation; however, those factors associated with cognitive human factors are less clear. Increased mechanisation and automation can place greater loads and demands on the older worker where cognitive decline is more subtle and varied between workers. Conclusion: Using historical and contemporary findings and the relationship between age, experience, and work performance is redrawn to include both cognitive skills and physical attributes to provide recommendations for future job design and worker needs. PMID:24688925
Load Composition Model Workflow (BPA TIP-371 Deliverable 1A)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chassin, David P.; Cezar, Gustavo V.
This project is funded under Bonneville Power Administration (BPA) Strategic Partnership Project (SPP) 17-005 between BPA and SLAC National Accelerator Laboratory. The project in a BPA Technology Improvement Project (TIP) that builds on and validates the Composite Load Model developed by the Western Electric Coordinating Council's (WECC) Load Modeling Task Force (LMTF). The composite load model is used by the WECC Modeling and Validation Work Group to study the stability and security of the western electricity interconnection. The work includes development of load composition data sets, collection of load disturbance data, and model development and validation. This work supports reliablemore » and economic operation of the power system. This report was produced for Deliverable 1A of the BPA TIP-371 Project entitled \\TIP 371: Advancing the Load Composition Model". The deliverable documents the proposed work ow for the Composite Load Model, which provides the basis for the instrumentation, data acquisition, analysis and data dissemination activities addressed by later phases of the project.« less
Response of the Alliance 1 Proof-of-Concept Airplane Under Gust Loads
NASA Technical Reports Server (NTRS)
Naser, A. S.; Pototzky, A. S.; Spain, C. V.
2001-01-01
This report presents the work performed by Lockheed Martin's Langley Program Office in support of NASA's Environmental Research Aircraft and Sensor Technology (ERAST) program. The primary purpose of this work was to develop and demonstrate a gust analysis method which accounts for the span-wise variation of gust velocity. This is important because these unmanned aircraft having high aspect ratios and low wing loading are very flexible, and fly at low speeds. The main focus of the work was therefore to perform a two-dimensional Power Spectrum Density (PSD) analysis of the Alliance 1 Proof-of-Concept Unmanned Aircraft, As of this writing, none of the aircraft described in this report have been constructed. They are concepts represented by analytical models. The process first involved the development of suitable structural and aeroelastic Finite Element Models (FEM). This was followed by development of a one-dimensional PSD gust analysis, and then the two-dimensional (PSD) analysis of the Alliance 1. For further validation and comparison, two additional analyses were performed. A two-dimensional PSD gust analysis was performed on a simplet MSC/NASTRAN example problem. Finally a one-dimensional discrete gust analysis was performed on Alliance 1. This report describes this process, shows the relevant comparisons between analytical methods, and discusses the physical meanings of the results.
[The role of psychosocial work factors in the development of musculoskeletal disorders in workers].
Bugajska, Joanna; Zołnierczyk-Zreda, Dorota; Jedryka-Góral, Anna
2011-01-01
The aim of the study was to determine the role of psychosocial work factors in the development of musculoskeletal disorders in workers. It should be stressed that over a decade these disorders have been the subject of studies because of complaints reported not only by workers performing heavy physical work or working in awkward, forced body posture. It has also been acknowledged that stress at work caused by various psychosocial work factors can significantly influence their development. One of the models, most popular nowadays, was used in the study. It takes into account various risk factors in the etiology of cervical spine disorders. Based on this model it was shown that certain psychosocial and cultural variables (e.g., work demands and control, individual variables, individual values, work group's culture) may constitute occupational stressors and, when combined with physical load factors, may lead to stress and musculoskeletal disorders. It was also indicated that such psychosocial work factors as excessive work demands (quantitative or qualitative), inadequate control at work or lack of social support are the most frequent sources of work-related stress. The article presents the results of some prospective studies in which the role of these factors in the development of musculoskeletal disorders has been considered. Apart from work properties (factors), the role of other psychological variables was shown; these include: work involvement, perfectionism, negative affectivity or work style, which in numerous studies turned out to be important risk factors in the development of musculoskeletal disorders. Finally, potential mechanisms underlying the relationships between psychosocial factors and musculoskeletal disorders were indicated. However, it was stressed that the majority of them still require to be confirmed in future descriptive or experimental studies.
Buford, Thomas W; Fillingim, Roger B; Manini, Todd M; Sibille, Kimberly T; Vincent, Kevin R; Wu, Samuel S
2015-07-01
As the U.S. population ages, efficacious interventions are needed to manage pain and maintain physical function among older adults with osteoarthritis (OA). Skeletal muscle weakness is a primary contributory factor to pain and functional decline among persons with OA, thus interventions are needed that improve muscle strength. High-load resistance exercise is the best-known method of improving muscle strength; however high-compressive loads commonly induce significant joint pain among persons with OA. Thus interventions with low-compressive loads are needed which improve muscle strength while limiting joint stress. This study is investigating the potential of an innovative training paradigm, known as Kaatsu, for this purpose. Kaatsu involves performing low-load exercise while externally-applied compression partially restricts blood flow to the active skeletal muscle. The objective of this randomized, single-masked pilot trial is to evaluate the efficacy and feasibility of chronic Kaatsu training for improving skeletal muscle strength and physical function among older adults. Participants aged ≥ 60 years with physical limitations and symptomatic knee OA will be randomly assigned to engage in a 3-month intervention of either (1) center-based, moderate-load resistance training, or (2) Kaatsu training matched for overall workload. Study dependent outcomes include the change in 1) knee extensor strength, 2) objective measures of physical function, and 3) subjective measures of physical function and pain. This study will provide novel information regarding the therapeutic potential of Kaatsu training while also informing about the long-term clinical viability of the paradigm by evaluating participant safety, discomfort, and willingness to continually engage in the intervention. Copyright © 2015 Elsevier Inc. All rights reserved.
NASA Technical Reports Server (NTRS)
Combi, M. R.; Kabin, K.; Gombosi, T. I.; DeZeeuw, D. L.; Powell, K. G.
1998-01-01
The first results for applying a three-dimensional multimedia ideal MHD model for the mass-loaded flow of Jupiter's corotating magnetospheric plasma past Io are presented. The model is able to consider simultaneously physically realistic conditions for ion mass loading, ion-neutral drag, and intrinsic magnetic field in a full global calculation without imposing artificial dissipation. Io is modeled with an extended neutral atmosphere which loads the corotating plasma torus flow with mass, momentum, and energy. The governing equations are solved using adaptive mesh refinement on an unstructured Cartesian grid using an upwind scheme for AHMED. For the work described in this paper we explored a range of models without an intrinsic magnetic field for Io. We compare our results with particle and field measurements made during the December 7, 1995, flyby of to, as published by the Galileo Orbiter experiment teams. For two extreme cases of lower boundary conditions at Io, our model can quantitatively explain the variation of density along the spacecraft trajectory and can reproduce the general appearance of the variations of magnetic field and ion pressure and temperature. The net fresh ion mass-loading rates are in the range of approximately 300-650 kg/s, and equivalent charge exchange mass-loading rates are in the range approximately 540-1150 kg/s in the vicinity of Io.
A predictive model of human performance.
NASA Technical Reports Server (NTRS)
Walters, R. F.; Carlson, L. D.
1971-01-01
An attempt is made to develop a model describing the overall responses of humans to exercise and environmental stresses for prediction of exhaustion vs an individual's physical characteristics. The principal components of the model are a steady state description of circulation and a dynamic description of thermal regulation. The circulatory portion of the system accepts changes in work load and oxygen pressure, while the thermal portion is influenced by external factors of ambient temperature, humidity and air movement, affecting skin blood flow. The operation of the model is discussed and its structural details are given.
General Nonlinear Ferroelectric Model v. Beta
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dong, Wen; Robbins, Josh
2017-03-14
The purpose of this software is to function as a generalized ferroelectric material model. The material model is designed to work with existing finite element packages by providing updated information on material properties that are nonlinear and dependent on loading history. The two major nonlinear phenomena this model captures are domain-switching and phase transformation. The software itself does not contain potentially sensitive material information and instead provides a framework for different physical phenomena observed within ferroelectric materials. The model is calibrated to a specific ferroelectric material through input parameters provided by the user.
NASA Astrophysics Data System (ADS)
Wang, Zi-Qing; Wang, Guo-Dong; Shen, Wei-Bo
2010-10-01
Multimotor transport is studied by Monte-Carlo simulation with consideration of motor detachment from the filament. Our work shows, in the case of low load, the velocity of multi-motor system can decrease or increase with increasing motor numbers depending on the single motor force-velocity curve. The stall force and run-length reduced greatly compared to other models. Especially in the case of low ATP concentrations, the stall force of multi motor transport even smaller than the single motor's stall force.
A Class of Broad-Band Dissipative Matching Networks Designed on an Insertion-Loss Basis
1952-01-25
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From canteen to lunch box: ergonomic demands in distribution of portion-packed hot food.
Dahlberg, Raymond; Bildt, Carina; Karlqvist, Lena
2003-01-01
The present case-study, which is rather small in number of subjects but has a broad perspective, is part of a larger investigation designed to initiate development processes in working life in one specific region in Sweden. This study may serve as an example of ergonomic fieldwork with a gender perspective. The overall aim was to examine the physical and psychosocial working conditions among a group of female hot food distributors, and to relate these conditions to other traditionally heavy work within the same working unit, as well as to suggest improvements. The study group consisted of ten female municipal employees in a provincial town. Structured interviews about the psychosocial working conditions, measurements of heart rate, ratings of self-reported perceived exertion and observations of one working day were performed. The overall impression from the study was that the food distributors in several aspects had a very difficult working situation that ought to be improved. The food distributors reported high psychological demands and low decision latitude, time pressure and dissatisfaction with not being able to live up to the pensioners' and the employer's expectations. They also had a high heart rate increase during work, which may be a risk factor for impaired health. Several short-term and long-term solutions were suggested to reduce and redistribute the total workload. The employer has attended to some suggested short-term solutions and the follow-up study showed that the working conditions had been improved. A reduction of cardiovascular load, as well as self-rated physical exertion, was noted and the work was perceived as substantially less stressful.
46 CFR 109.525 - Cranes: Working loads.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 46 Shipping 4 2011-10-01 2011-10-01 false Cranes: Working loads. 109.525 Section 109.525 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS OPERATIONS Cranes § 109.525 Cranes: Working loads. The master or person in charge shall ensure that tables...
46 CFR 109.525 - Cranes: Working loads.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 46 Shipping 4 2014-10-01 2014-10-01 false Cranes: Working loads. 109.525 Section 109.525 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS OPERATIONS Cranes § 109.525 Cranes: Working loads. The master or person in charge shall ensure that tables...
46 CFR 109.525 - Cranes: Working loads.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 46 Shipping 4 2013-10-01 2013-10-01 false Cranes: Working loads. 109.525 Section 109.525 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS OPERATIONS Cranes § 109.525 Cranes: Working loads. The master or person in charge shall ensure that tables...
46 CFR 109.525 - Cranes: Working loads.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 4 2010-10-01 2010-10-01 false Cranes: Working loads. 109.525 Section 109.525 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS OPERATIONS Cranes § 109.525 Cranes: Working loads. The master or person in charge shall ensure that tables...
46 CFR 109.525 - Cranes: Working loads.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 46 Shipping 4 2012-10-01 2012-10-01 false Cranes: Working loads. 109.525 Section 109.525 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS OPERATIONS Cranes § 109.525 Cranes: Working loads. The master or person in charge shall ensure that tables...
[Information value of "additional tasks" method to evaluate pilot's work load].
Gorbunov, V V
2005-01-01
"Additional task" method was used to evaluate pilot's work load in prolonged flight. Calculated through durations of latent periods of motor responses, quantitative criterion of work load is more informative for objective evaluation of pilot's involvement in his piloting functions rather than of other registered parameters.
Stress and Performance: Effects of Subjective Work Load and Time Urgency.
ERIC Educational Resources Information Center
Friend, Kenneth E.
1982-01-01
Measured subjective work load, time urgency, and other stress/motivation variables for management personnel taking a demanding problem-solving exam. Data suggest increases in psychological stresses like subjectively high work load and time urgency uniformly impair performance across the whole range of these variables. (Author)
Svedmark, Åsa; Björklund, Martin; Häger, Charlotte K; Sommar, Johan Nilsson; Wahlström, Jens
2018-05-28
The aim was to evaluate if pain, disability, and work productivity are influenced by physical and psychosocial work exposures as well as by stress, up to 1 year after a randomized controlled trial treatment intervention, and to determine whether any such association differed between treatment and control groups. Ninety-seven working women suffering non-specific neck pain (n = 67 treatment group, n = 30 control group) were followed from end of treatment intervention and at 9- and 15-month follow-ups, respectively. Physical and psychosocial exposures, as well as perceived stress, were assessed after the treatment intervention. Pain, neck disability, and work productivity were assessed at baseline, after intervention 3 months later and at 9- and 15-month follow-ups. Longitudinal assessment was conducted using the exposure level at 3 months as predictor of pain, disability, and work productivity at 3, 9, and 15 months, respectively. Mixed models were used to estimate longitudinal associations, accounting for within-individual correlation of repeated outcome measures by incorporation of a random intercept. Age and duration of neck pain were adjusted for in all models. To evaluate group differences, interactions between exposures and treatment groups were estimated. High perceived stress was associated with more neck pain, more neck disability, and decreased work productivity in both cross-sectional and longitudinal analyses. High 'control of decision' was associated with less neck pain, less neck disability, and higher work productivity in cross-sectional analyses but only to less disability and higher productivity in longitudinal analyses. Shoulder/arm load was the only physical exposure variable that was significantly associated with work productivity in the univariate analyses. Only small differences were observed between treatment and control groups. High perceived stress and low 'control of decision' were associated with more neck pain, increased neck disability, and decreased work productivity. Treatment interventions for individuals with neck pain should take into account psychosocial workplace exposures and stress to improve intermediate and long-term results.
de Fockert, Jan W; Bremner, Andrew J
2011-12-01
An unexpected stimulus often remains unnoticed if attention is focused elsewhere. This inattentional blindness has been shown to be increased under conditions of high memory load. Here we show that increasing working memory load can also have the opposite effect of reducing inattentional blindness (i.e., improving stimulus detection) if stimulus detection is competing for attention with a concurrent visual task. Participants were required to judge which of two lines was the longer while holding in working memory either one digit (low load) or six digits (high load). An unexpected visual stimulus was presented once alongside the line judgment task. Detection of the unexpected stimulus was significantly improved under conditions of higher working memory load. This improvement in performance prompts the striking conclusion that an effect of cognitive load is to increase attentional spread, thereby enhancing our ability to detect perceptual stimuli to which we would normally be inattentionally blind under less taxing cognitive conditions. We discuss the implications of these findings for our understanding of the relationship between working memory and selective attention. Copyright © 2011 Elsevier B.V. All rights reserved.
The evaluation of team lifting on physical work demands and workload in ironworkers.
van der Molen, Henk F; Visser, Steven; Kuijer, P Paul F M; Faber, Gert; Hoozemans, Marco J M; van Dieën, Jaap H; Frings-Dresen, Monique H W
2012-01-01
Lifting and carrying heavy loads occur frequently among ironworkers and result in high prevalence and incidence rates of low back complaints, injuries and work-disability. From a health perspective, little information is available on the effect of team lifting on work demands and workload. Therefore, the objective of this study was to compare the effects of team lifting of maximally 50 kg by two ironworkers (T50) with team lifting of maximally 100 kg by four ironworkers (T100). This study combined a field and laboratory study with the following outcome measures: duration and frequency of tasks and activities, energetic workload, perceived discomfort and maximal compression forces (Fc peak) on the low back. The physical work demands and workload of an individual iron worker during manual handling of rebar materials of 100 kg with four workers did not differ from the manual handling of rebar materials of 50 kg with two workers, with the exception of low back discomfort and Fc peak. The biomechanical workload of the low back exceeded for both T50 and T100 the NIOSH threshold limit of 3400N. Therefore, mechanical transport or other effective design solutions should be considered to reduce the biomechanical workload of the low back and the accompanying health risks among iron workers.
[Evaluation of the capacity of work using upper limbs after radical latero-cervical surgery].
Capodaglio, P; Strada, M R; Grilli, C; Lodola, E; Panigazzi, M; Bernardo, G; Bazzini, G
1998-01-01
Evaluation of arm work capacity after radical neck surgery. The aim of this paper is to describe an approach for the assessment of work capacity in patients who underwent radical neck surgery, including those treated with radiation therapy. Nine male patients, who underwent radical neck surgery 2 months before being referred to our Unit, participated in the study. In addition to manual muscle strength test, we performed the following functional evaluations: 0-100 Constant scale for shoulder function; maximal shoulder strength in adduction/abduction and intrarotation/extrarotation; instrumental. We measured maximal isokinetic strength (10 repetitions) with a computerized dynamometer (Lido WorkSET) set at 100 degrees/sec. During the rehabilitation phase, the patients' mechanical parameters, the perception of effort, pain or discomfort, and the range of movement were monitored while performing daily/occupational task individually chosen on the simulator (Lido WorkSET) under isotonic conditions. On this basis, patients were encouraged to return to levels of daily physical activities compatible with the individual tolerable work load. The second evaluation at 2 month confirmed that the integrated rehabilitation protocol successfully increased patients' capacities and "trust" in their physical capacity. According to the literature, the use of isokinetic and isotonic exercise programs appears to decrease shoulder rehabilitation time. In our experience an excellent compliance has been noted. One of the advantages of the method proposed is to provide quantitative reports of the functional capacity and therefore to facilitate return-to-work of patients who underwent radical neck surgery.
Effects of load on the guidance of visual attention from working memory.
Zhang, Bao; Zhang, John X; Huang, Sai; Kong, Lingyue; Wang, Suiping
2011-12-08
An active recent line of research on working memory and attention has shown that the visual attention can be top-down guided by working memory contents. The present study examined whether the guidance effect is modulated by memory load, i.e., the amount of information maintained in working memory. In a set of three experiments, participants were asked to perform a visual search task while maintaining several objects in working memory. The memory-driven attentional guidance effect was observed in all experiments when there were spare working memory resources. When memory load was increased from one item to two items, there was no sign that the guidance effect was attenuated. When load was further increased to four items, the guidance effect disappeared completely, indicating a clear impact of memory load on attentional guidance. Copyright © 2011 Elsevier Ltd. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Qian, Mr. Suxin; Gluesenkamp, Kyle R; Hwang, Dr. Yunho
Adsorption chillers are capable of utilizing inexpensive or free low grade thermal energy such as waste heat and concentrated solar thermal energy. Recently developed low regeneration temperature working pairs allow adsorption chillers to be driven by even lower temperature sources such as engine coolant and flat plate solar collectors. In this work, synthetic zeolite/water was implemented into a 3kW adsorption chiller test facility driven by hot water at 70 C. The zeolite was coated onto two fin-and-tube heat exchangers, with heat recovery employed between the two. Cyclic steady state parametric studies were experimentally conducted to evaluate the chiller's performance, resultingmore » in a cooling coefficient of performance (COP) ranging from 0.1 to 0.6 at different operating conditions. Its performance was compared with published values for other low regeneration temperature working pairs. The physical limitations of the synthetic zeolite revealed by parametric study results were then discussed. A novel operating control strategy was proposed based on the unique characteristics of synthetic zeolite. In addition, a physics-based COP prediction model was derived to predict the performance of the chiller under equilibrium loading, and was validated by the experiment results. This analytical expression can be used to estimate the cyclic steady state performance for future studies.« less
NASA Astrophysics Data System (ADS)
Papantonakis, Michael R.; Nguyen, Viet K.; Furstenberg, Robert; White, Caitlyn; Shuey, Melissa; Kendziora, Christopher A.; McGill, R. Andrew
2017-05-01
Knowledge of the persistence of trace explosives materials is critical to aid the security community in designing detection methods and equipment. The physical and environmental factors affecting the lifetimes of particles include temperature, airflow, interparticle distance, adlayers, humidity, particle field size and vapor pressure. We are working towards a complete particle persistence model that captures the relative importance of these effects to allow the user, with known environmental conditions, to predict particle lifetimes for explosives or other chemicals. In this work, particles of explosives are sieved onto smooth glass substrates using particle sizes and loadings relevant to those deposited by fingerprint deposition. The coupon is introduced into a custom flow cell and monitored under controlled airflow, humidity and temperature. Photomicroscopy images of the sample taken at fixed time intervals are analyzed to monitor particle sublimation and characterized as a size-independent radial sublimation velocity for each particle in the ensemble. In this paper we build on previous work by comparing the relationship between sublimation of different materials and their vapor pressures. We also describe the influence of a sebum adlayer on particle sublimation, allowing us to better model `real world' samples.
Weikert, Madeline; Motl, Robert W; Suh, Yoojin; McAuley, Edward; Wynn, Daniel
2010-03-15
Motion sensors such as accelerometers have been recognized as an ideal measure of physical activity in persons with MS. This study examined the hypothesis that accelerometer movement counts represent a measure of both physical activity and walking mobility in individuals with MS. The sample included 269 individuals with a definite diagnosis of relapsing-remitting MS who completed the Godin Leisure-Time Exercise Questionnaire (GLTEQ), International Physical Activity Questionnaire (IPAQ), Multiple Sclerosis Walking Scale-12 (MSWS-12), Patient Determined Disease Steps (PDDS), and then wore an ActiGraph accelerometer for 7days. The data were analyzed using bivariate correlation and confirmatory factor analysis. The results indicated that (a) the GLTEQ and IPAQ scores were strongly correlated and loaded significantly on a physical activity latent variable, (b) the MSWS-12 and PDDS scores strongly correlated and loaded significantly on a walking mobility latent variable, and (c) the accelerometer movement counts correlated similarly with the scores from the four self-report questionnaires and cross-loaded on both physical activity and walking mobility latent variables. Our data suggest that accelerometers are measuring both physical activity and walking mobility in persons with MS, whereas self-report instruments are measuring either physical activity or walking mobility in this population.
Compilation of load spectrum of loader drive axle
NASA Astrophysics Data System (ADS)
Wei, Yongxiang; Zhu, Haoyue; Tang, Heng; Yuan, Qunwei
2018-03-01
In order to study the preparation method of gear fatigue load spectrum for loaders, the load signal of four typical working conditions of loader is collected. The signal that reflects the law of load change is obtained by preprocessing the original signal. The torque of the drive axle is calculated by using the rain flow counting method. According to the operating time ratio of each working condition, the two dimensional load spectrum based on the real working conditions of the drive axle of loader is established by the cycle extrapolation and synthesis method. The two-dimensional load spectrum is converted into one-dimensional load spectrum by means of the mean of torque equal damage method. Torque amplification includes the maximum load torque of the main reduction gear. Based on the theory of equal damage, the accelerated cycles are calculated. In this way, the load spectrum of the loading condition of the drive axle is prepared to reflect loading condition of the loader. The load spectrum can provide reference for fatigue life test and life prediction of loader drive axle.
Nutrition and muscle loss in humans during spaceflight
NASA Technical Reports Server (NTRS)
Stein, T. P.
1999-01-01
The protein loss in humans during spaceflight is partly due to a normal adaptive response to a decreased work load on the muscles involved in weight bearing. The process is mediated by changes in prostaglandin release, secondary to the decrease in tension on the affected muscles. On missions, where there is a high level of physical demands on the astronauts, there tends to be an energy deficit, which adds to the muscle protein loss and depletes the body fat reserves. While the adaptive response is a normal part of homeostasis, the additional protein loss from an energy deficit can, in the long run, have a negative effect on health and capability of humans to live and work in space and afterward return to Earth.
Experiments with bosonic atoms for quantum gas assembly
NASA Astrophysics Data System (ADS)
Brown, Mark; Lin, Yiheng; Lester, Brian; Kaufman, Adam; Ball, Randall; Brossard, Ludovic; Isaev, Leonid; Thiele, Tobias; Lewis-Swan, Robert; Schymik, Kai-Niklas; Rey, Ana Maria; Regal, Cindy
2017-04-01
Quantum gas assembly is a promising platform for preparing and observing neutral atom systems on the single-atom level. We have developed a toolbox that includes ground-state laser cooling, high-fidelity loading techniques, addressable spin control, and dynamic spatial control and coupling of atoms. Already, this platform has enabled us to pursue a number of experiments studying entanglement and interference of pairs of bosonic atoms. We discuss our recent work in probabilistically entangling neutral atoms via interference, measurement, and post-selection as well as our future pursuits of interesting spin-motion dynamics of larger arrays of atoms. This work was supported by the David and Lucile Packard Foundation, National Science Foundation Physics Frontier Centers, and the National Defense Science and Engineering Graduate Fellowships program.
NASA Astrophysics Data System (ADS)
Kumar, Praveen; Mahesh, Krishnan
2014-11-01
Crashback is an operating condition to quickly stop a propelled vehicle, where the propeller is rotated in the reverse direction to yield a negative thrust. In crashback, the freestream interacts with the strong reverse flow from the propeller leading to massive flow separation and highly unsteady loads. We have used Large-Eddy Simulation (LES) in recent years to accurately simulate the flowfield in crashback around a stand-alone open propeller, hull-attached (posterior alone) open propeller and a ducted propeller with stator blades. This talk will discuss our work towards LES of crashback inclusive of the entire hull. The results will be compared to available experimental data, and the flow physics will be discussed. This work is supported by the Office of Naval Research.
Ergonomics and the physiotherapist: a report on a research project on working postures.
Bullock, M I; Lanchester, J J
1969-09-01
In a series of lectures on biomechanical principles, Professor E. R. Tichauer, an authority on man-machine-task systems, stated: "Only a few years ago, the physical work load imposed on the individual employee was much heavier than is the case today, but it was, in many occupations, fairly evenly distributed over the entire musculo skeletal system. Today, the total energy demanded from man in the performance of an industrial task has often been reduced, but stress is concentrated on individual and small components of the worker's anatomy," The techniques for combating these new stresses are found in the science of ergonomics (Hopkins 1966). Copyright © 1969 Australian Physiotherapy Association. Published by . All rights reserved.
The Role of Cognitive Load in Intentional Forgetting Using the Think/No-Think Task.
Noreen, Saima; de Fockert, Jan W
2017-01-01
We investigated the role of cognitive control in intentional forgetting by manipulating working memory load during the think/no-think task. In two experiments, participants learned a series of cue-target word pairs and were asked to recall the target words associated with some cues or to avoid thinking about the target associated with other cues. In addition to this, participants also performed a modified version of the n-back task which required them to respond to the identity of a single target letter present in the currently presented cue word (n = 0 condition, low working memory load), and in either the previous cue word (n = 1 condition, high working memory load, Experiment 1) or the cue word presented two trials previously (n = 2 condition, high working memory load, Experiment 2). Participants' memory for the target words was subsequently tested using same and novel independent probes. In both experiments it was found that although participants were successful at forgetting on both the same and independent-probe tests in the low working memory load condition, they were only successful at forgetting on the same-probe test in the high working memory load condition. We argue that our findings suggest that the high load working memory task diverted attention from direct suppression and acted as an interference-based strategy. Thus, when cognitive resources are limited participants can switch between the strategies they use to prevent unwanted memories from coming to mind.
Physics Based Model for Cryogenic Chilldown and Loading. Part I: Algorithm
NASA Technical Reports Server (NTRS)
Luchinsky, Dmitry G.; Smelyanskiy, Vadim N.; Brown, Barbara
2014-01-01
We report the progress in the development of the physics based model for cryogenic chilldown and loading. The chilldown and loading is model as fully separated non-equilibrium two-phase flow of cryogenic fluid thermally coupled to the pipe walls. The solution follow closely nearly-implicit and semi-implicit algorithms developed for autonomous control of thermal-hydraulic systems developed by Idaho National Laboratory. A special attention is paid to the treatment of instabilities. The model is applied to the analysis of chilldown in rapid loading system developed at NASA-Kennedy Space Center. The nontrivial characteristic feature of the analyzed chilldown regime is its active control by dump valves. The numerical predictions are in reasonable agreement with the experimental time traces. The obtained results pave the way to the development of autonomous loading operation on the ground and space.
Faber, G S; Kingma, I; Kuijer, P P F M; van der Molen, H F; Hoozemans, M J M; Frings-Dresen, M H W; van Dieën, J H
2009-09-01
The goal of this study was to compare the effects of the task variables block mass, working height and one- vs. two-handed block handling on low back and shoulder loading during masonry work. In a mock-up of a masonry work site, nine masonry workers performed one- and two-handed block-lifting and block-placing tasks at varying heights (ranging from floor to shoulder level) with blocks of varying mass (ranging from 6 to 16 kg). Kinematics and ground reaction forces were measured and used in a 3-D linked segment model to calculate low back and shoulder loading. Increasing lifting height appeared to be the most effective way to reduce low back loading. However, working at shoulder level resulted in relatively high shoulder loading. Therefore, it was recommended to organise masonry work in such a way that blocks are handled with the hands at about iliac crest height as much as possible.
Briggs, Andrew M; Bragge, Peter; Smith, Anne J; Govil, Dhruv; Straker, Leon M
2009-01-01
Spinal pain is a significant occupational health issue. Whilst neck pain and low back pain have received considerable attention, thoracic spinal pain (TSP) has not. The objective of this study was to systematically identify and report the evidence describing the prevalence and correlates of TSP within occupational groups. This literature review systematically searched for reports of TSP prevalence and associated factors for TSP in working adult cohorts using nine electronic databases. Studies were evaluated for level of evidence and epidemiologic data were narratively synthesised. 52 studies were identified describing 65 cohorts covering manual labourers, office workers, health professionals, manufacturing and industrial workers, drivers, military personnel and performing artists. Prevalence varied with occupational group and time period. One year prevalence of TSP ranged from 3.0-55.0%, with most occupational groups having medians around 30%. Significant odds ratios for individual (concurrent musculoskeletal disorders, exercising, pre-menstrual tension and female gender), general work-related (high work load, high work intensity, perceiving ergonomic problems in the workplace, working in some specialised areas, performing boring/tedious work tasks, certain year levels of study, employment duration, driving specialised vehicles, and a high number of flying hours), physical work-related (manual physiotherapy tasks, climbing stairs and high physical stress) and psychosocial work-related (perceived risk of injury and high mental pressure) factors were reported. The high median prevalence rates suggest TSP may be a significant occupational health problem. The multiple domains of associated factors point to the need for prospective research encompassing these domains to inform targeted occupational interventions.
Career Implications of Doctoral Social Work Student Debt Load
ERIC Educational Resources Information Center
Begun, Audrey L.; Carter, James R.
2017-01-01
Although research has been conducted in other professional disciplines, social work has yet to explore how doctoral student debt load influences career development. This exploratory study surveyed 281 social work doctoral students and recent graduates, 75 BSW and MSW program leaders, and 24 doctoral program leaders about debt load, career choices,…
Nindl, Bradley C; Jones, Bruce H; Van Arsdale, Stephanie J; Kelly, Karen; Kraemer, William J
2016-01-01
This article summarizes presentations from a 2014 United States Department of Defense (DoD) Health Affairs Women in Combat symposium addressing physiological, musculoskeletal injury, and optimized physical training considerations from the operational physical performance section. The symposium was held to provide a state-of-the-science meeting on the U.S. DoD's rescinding of the ground combat exclusion policy opening up combat-centric occupations to women. Physiological, metabolic, body composition, bone density, cardiorespiratory fitness, and thermoregulation differences between men and women were briefly reviewed. Injury epidemiological data are presented within military training and operational environments demonstrating women to be at a higher risk for musculoskeletal injuries than men. Physical training considerations for improved muscle strength and power, occupational task performance, load carriage were also reviewed. Particular focus of this article was given to translating physiological and epidemiological findings from the literature on these topics toward actionable guidance and policy recommendations for military leaders responsible for military physical training doctrine: (1) inclusion of resistance training with special emphasis on strength and power development (i.e., activation of high-threshold motor units and recruitment of type II high-force muscle fibers), upper-body strength development, and heavy load carriage, (2) moving away from "field expediency" as the major criteria for determining military physical training policy and training implementation, (3) improvement of load carriage ability with emphasis placed on specific load carriage task performance, combined with both resistance and endurance training, and (4) providing greater equipment resources, coaching assets, and increased training time dedicated to physical readiness training. Reprint & Copyright © 2016 Association of Military Surgeons of the U.S.
NASA Astrophysics Data System (ADS)
Pan, Edward A.
Science, technology, engineering, and mathematics (STEM) education is a national focus. Engineering education, as part of STEM education, needs to adapt to meet the needs of the nation in a rapidly changing world. Using computer-based visualization tools and corresponding 3D printed physical objects may help nontraditional students succeed in engineering classes. This dissertation investigated how adding physical or virtual learning objects (called manipulatives) to courses that require mental visualization of mechanical systems can aid student performance. Dynamics is one such course, and tends to be taught using lecture and textbooks with static diagrams of moving systems. Students often fail to solve the problems correctly and an inability to mentally visualize the system can contribute to student difficulties. This study found no differences between treatment groups on quantitative measures of spatial ability and conceptual knowledge. There were differences between treatments on measures of mechanical reasoning ability, in favor of the use of physical and virtual manipulatives over static diagrams alone. There were no major differences in student performance between the use of physical and virtual manipulatives. Students used the physical and virtual manipulatives to test their theories about how the machines worked, however their actual time handling the manipulatives was extremely limited relative to the amount of time they spent working on the problems. Students used the physical and virtual manipulatives as visual aids when communicating about the problem with their partners, and this behavior was also seen with Traditional group students who had to use the static diagrams and gesture instead. The explanations students gave for how the machines worked provided evidence of mental simulation; however, their causal chain analyses were often flawed, probably due to attempts to decrease cognitive load. Student opinions about the static diagrams and dynamic models varied by type of model (static, physical, virtual), but were generally favorable. The Traditional group students, however, indicated that the lack of adequate representation of motion in the static diagrams was a problem, and wished they had access to the physical and virtual models.
Working Memory Load Affects Processing Time in Spoken Word Recognition: Evidence from Eye-Movements
Hadar, Britt; Skrzypek, Joshua E.; Wingfield, Arthur; Ben-David, Boaz M.
2016-01-01
In daily life, speech perception is usually accompanied by other tasks that tap into working memory capacity. However, the role of working memory on speech processing is not clear. The goal of this study was to examine how working memory load affects the timeline for spoken word recognition in ideal listening conditions. We used the “visual world” eye-tracking paradigm. The task consisted of spoken instructions referring to one of four objects depicted on a computer monitor (e.g., “point at the candle”). Half of the trials presented a phonological competitor to the target word that either overlapped in the initial syllable (onset) or at the last syllable (offset). Eye movements captured listeners' ability to differentiate the target noun from its depicted phonological competitor (e.g., candy or sandal). We manipulated working memory load by using a digit pre-load task, where participants had to retain either one (low-load) or four (high-load) spoken digits for the duration of a spoken word recognition trial. The data show that the high-load condition delayed real-time target discrimination. Specifically, a four-digit load was sufficient to delay the point of discrimination between the spoken target word and its phonological competitor. Our results emphasize the important role working memory plays in speech perception, even when performed by young adults in ideal listening conditions. PMID:27242424
Morikawa, Yuko; Kitaoka-Higashiguchi, Kazuyo; Tanimoto, Chie; Hayashi, Midori; Oketani, Reiko; Miura, Katsuyuki; Nishijo, Muneko; Nakagawa, Hideaki
2005-09-01
The present study investigated the effects of job stress on cellular immune function, such as NK cell activity and NK cell subsets. The participants were 61 female nurses aged 23-59, who worked in a public psychiatric hospital in Ishikawa, Japan. Each subject completed the Nursing Job Stressor Scale (NJSS) and their NK cell activity and lymphocyte surface antigens (CD16+56+) were evaluated as immune system parameters. The NJSS has seven subscales: conflict with other nursing staff, nursing role conflict, conflict with physicians or autonomy, conflict with death or dying, quantitative work load, qualitative work load and conflict with patients. Factors influencing NK cell activity, and the proportion and cell counts of CD16+56+ lymphocytes were evaluated. Increase in quantitative work load significantly decreased NK cell activity. Conversely, no linear relationship was observed between qualitative work load and immunological variables, with the highest percentage of CD16+56+ lymphocytes observed among participants in the medium work load group. The other five NJSS subscales did not relate to immune parameters. In conclusion, the results suggest that perceived job strains, particularly quantitative work load, decreased NK cell function.
NASA Technical Reports Server (NTRS)
Sokolova, Z. A.
1980-01-01
The influence of sinusoidal modulated currents was studied and physical loads on the nucleic acid content and the nucleotide composition of the total RNA in muscles of rats of various ages under conditions of hypodynamia were measured. Methodology utilized is described and conclusions are presented.
Understanding of self-terminating pulse generation using silicon controlled rectifier and RC load
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chang, Chris, E-mail: chrischang81@gmail.com; Karunasiri, Gamani, E-mail: karunasiri@nps.edu; Alves, Fabio, E-mail: falves@alionscience.com
2016-01-15
Recently a silicon controlled rectifier (SCR)-based circuit that generates self-terminating voltage pulses was employed for the detection of light and ionizing radiation in pulse mode. The circuit consisted of a SCR connected in series with a RC load and DC bias. In this paper, we report the investigation of the physics underlying the pulsing mechanism of the SCR-based. It was found that during the switching of SCR, the voltage across the capacitor increased beyond that of the DC bias, thus generating a reverse current in the circuit, which helped to turn the SCR off. The pulsing was found to bemore » sustainable only for a specific range of RC values depending on the SCR’s intrinsic turn-on/off times. The findings of this work will help to design optimum SCR based circuits for pulse mode detection of light and ionizing radiation without external amplification circuitry.« less
Pushing, pulling and manoeuvring an industrial cart: a psychophysiological study.
Giagloglou, Evanthia; Radenkovic, Milan; Brankovic, Sasa; Antoniou, Panagiotis; Zivanovic-Macuzic, Ivana
2017-09-18
One of the most frequent manual occupational tasks involves the pushing and pulling of a cart. Although several studies have associated health risks with pushing and pulling, the effects are not clear since occupational tasks have social, cognitive and physical components. The present work investigates a real case of a pushing and pulling occupational task from a manufacturing company. The study initially characterizes the case in accordance with Standard No. ISO 11228-2:2007 as low risk. An experiment with 14 individuals during three modalities of pushing and pulling was performed in order to further investigate the task with the application of electrophysiology. At the end, a simple questionnaire was given. The results show electrophysiological differences among the three modalities of pushing and pulling, with a major difference between action with no load and fully loaded with a full range of motions on the cart to handle.
Atomistic Origin of Deformation Twinning in Biomineral Aragonite.
Liu, Jialin; Huang, Zaiwang; Pan, Zhiliang; Wei, Qiuming; Li, Xiaodong; Qi, Yue
2017-03-10
Deformation twinning rarely occurs in mineral materials which typically show brittle fracture. Surprisingly, it has recently been observed in the biomineral aragonite phase in nacre under high rate impact loading. In this Letter, the twinning tendency and the competition between fracture and deformation twinning were revealed by first principles calculations. The ratio of the unstable stacking fault energy and the stacking fault energy in orthorhombic aragonite is hitherto the highest in a broad range of metallic and oxide materials. The underlining physics for this high ratio is the multineighbor shared ionic bonds and the unique relaxation process during sliding in the aragonite structure. Overall, the unique deformation twining along with other highly coordinated deformation mechanisms synergistically work in the hierarchical structure of nacre, leading to the remarkable strengthening and toughening of nacre upon dynamic loading, and thus protecting the mother-of-pearl from predatory attacks.
NASA Astrophysics Data System (ADS)
Naz, M.; Nasiri, N.; Ikram, M.; Nafees, M.; Qureshi, M. Z.; Ali, S.; Tricoli, A.
2017-11-01
The work aimed to prepare silver nanoparticles (Ag-NPs) from silver nitrate and various concentrations of the seed extract ( Setaria verticillata) by a green synthetic route. The chemical and physical properties of the resulting Ag-NPs were investigated by X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared (FTIR) spectrometry and ultraviolet-visible (UV-Vis) spectrophotometry. Anticancer activity of Ag-NPs (5-20 nm) had dose-dependent cytotoxic effect against breast cancer (MCF7-FLV) cells. The in vitro toxicity was studied on adult earthworms (Lumbricina) resulting in statistically significant ( P < 0.05) inhibition. The prepared NPs were loaded with hydrophilic anticancer drugs (ACD), doxorubicin (DOX) and daunorubicin (DNR), for developing a novel drug delivery carrier having significant adsorption capacity and efficiency to remove the side effects of the medicines effective for leukemia chemotherapy.
Wells, Gary G.; Ledesma-Aguilar, Rodrigo; McHale, Glen; Sefiane, Khellil
2015-01-01
Heat engines are based on the physical realization of a thermodynamic cycle, most famously the liquid–vapour Rankine cycle used for steam engines. Here we present a sublimation heat engine, which can convert temperature differences into mechanical work via the Leidenfrost effect. Through controlled experiments, quantified by a hydrodynamic model, we show that levitating dry-ice blocks rotate on hot turbine-like surfaces at a rate controlled by the turbine geometry, temperature difference and solid material properties. The rotational motion of the dry-ice loads is converted into electric power by coupling to a magnetic coil system. We extend our concept to liquid loads, generalizing the realization of the new engine to both sublimation and the instantaneous vapourization of liquids. Our results support the feasibility of low-friction in situ energy harvesting from both liquids and ices. Our concept is potentially relevant in challenging situations such as deep drilling, outer space exploration or micro-mechanical manipulation. PMID:25731669
Wells, Gary G; Ledesma-Aguilar, Rodrigo; McHale, Glen; Sefiane, Khellil
2015-03-03
Heat engines are based on the physical realization of a thermodynamic cycle, most famously the liquid-vapour Rankine cycle used for steam engines. Here we present a sublimation heat engine, which can convert temperature differences into mechanical work via the Leidenfrost effect. Through controlled experiments, quantified by a hydrodynamic model, we show that levitating dry-ice blocks rotate on hot turbine-like surfaces at a rate controlled by the turbine geometry, temperature difference and solid material properties. The rotational motion of the dry-ice loads is converted into electric power by coupling to a magnetic coil system. We extend our concept to liquid loads, generalizing the realization of the new engine to both sublimation and the instantaneous vapourization of liquids. Our results support the feasibility of low-friction in situ energy harvesting from both liquids and ices. Our concept is potentially relevant in challenging situations such as deep drilling, outer space exploration or micro-mechanical manipulation.
Samani, Afshin; Holtermann, Andreas; Søgaard, Karen; Holtermann, Andreas; Madeleine, Pascal
2012-01-01
The aim was to investigate the effect of ergonomics guidelines on muscular activity, postural and cardiovascular load during cleaning. Eighteen cleaners performed 10 min of cleaning tasks in two locations; three min in a laboratory and seven min in a lecture room. All participants performed the task with or without focusing on ergonomics guidelines (ergonomics/non-ergonomics session). Bipolar surface electromyography was recorded bilaterally from upper trapezius and erector spinae muscles. A tri-axial accelerometer package was mounted on the low back (L5-S1) to measure postural changes, and the cardiovascular load was estimated by electrocardiogram. Ergonomics sessions resulted in lower muscular load, a more complex pattern of muscular activity, lower range of motion and angular velocity of the trunk as well as lower cardiovascular load compared with non-ergonomics sessions (p < 0.05). The study highlighted the multiple musculoskeletal and cardiovascular benefits of following ergonomics guidelines during cleaning tasks. This study investigated the effects of following instructive ergonomics guidelines during cleaning tasks (daily curriculum of cleaning including mopping, sweeping, changing trash bins and cleaning of desks and blackboards). Following the ergonomics guidelines reduces the general workload and induces a more complex pattern of muscular activity. The study contributes with novel knowledge concerning ergonomics guidelines and work techniques.
Zhang, Yuanhao; Pan, Xiuwei; Shi, Zhen; Cai, Haibo; Gao, Yun; Zhang, Weian
2018-04-01
Stem cell factor (SCF) is considered as a commonly indispensable cytokine for proliferation of haematopoietic stem cells (HSCs), which is used in large dosages during ex vivo culture. The work presented here aimed to reduce the consumption of SCF by sustained release but still support cells proliferation and maintain the multipotency of HSCs. Stem cell factor was physically encapsulated within a hyaluronic acid/gelatin double network (HGDN) hydrogel to achieve a slow release rate. CD34 + cells were cultured within the SCF-loaded HGDN hydrogel for 14 days. The cell number, phenotype and functional capacity were investigated after culture. The HGDN hydrogels had desirable properties and encapsulated SCF kept being released for more than 6 days. SCF remained the native bioactivity, and the proliferation of HSCs within the SCF-loaded HGDN hydrogel was not affected, although the consumption of SCF was only a quarter in comparison with the conventional culture. Moreover, CD34 + cells harvested from the SCF-loaded HGDN hydrogels generated more multipotent colony-forming units (CFU-GEMM). The data suggested that the SCF-loaded HGDN hydrogel could support ex vivo culture of HSCs, thus providing a cost-effective culture protocol for HSCs. © 2017 John Wiley & Sons Ltd.
An Apparatus to Demonstrate Linear and Nonlinear Oscillations of a Pendulum
ERIC Educational Resources Information Center
Mayer, V. V.; Varaksina, E. I.
2016-01-01
A physical pendulum with a magnetic load is proposed for comparison of linear and nonlinear oscillations. The magnetic load is repelled by permanent magnets which are disposed symmetrically relative to the load. It is established that positions of the pendulum and the magnets determine the dependence of restoring force on displacement of the load.…
Work Status, Work Satisfaction, and Blood Pressure Among Married Black and White Women
ERIC Educational Resources Information Center
Hauenstein, Louise S.; And Others
1977-01-01
This study examined blood pressure levels of married women in relation to such work-related variables as work load, satisfaction with work, reported strain, and evaluated performance. Differences in work load were unrelated to blood pressure levels. However, currently unemployed working women had lower levels. (Author)
Cognitive Load Theory: An Empirical Study of Anxiety and Task Performance in Language Learning
ERIC Educational Resources Information Center
Chen, I-Jung; Chang, Chi-Cheng
2009-01-01
Introduction: This study explores the relationship among three variables--cognitive load, foreign language anxiety, and task performance. Cognitive load refers to the load imposed on working memory while performing a particular task. The authors hypothesized that anxiety consumes the resources of working memory, leaving less capacity for cognitive…
Ihne, Jessica L; Gallagher, Natalie M; Sullivan, Marie; Callicott, Joseph H; Green, Adam E
2016-01-01
Perhaps the most widely studied effect to emerge from the combination of neuroimaging and human genetics is the association of the COMT-Val(108/158)Met polymorphism with prefrontal activity during working memory. COMT-Val is a putative risk factor in schizophrenia, which is characterized by disordered prefrontal function. Work in healthy populations has sought to characterize mechanisms by which the valine (Val) allele may lead to disadvantaged prefrontal cognition. Lower activity in methionine (Met) carriers has been interpreted as advantageous neural efficiency. Notably, however, studies reporting COMT effects on neural efficiency have generally not reported working memory performance effects. Those studies have employed relatively low/easy working memory loads. Higher loads are known to elicit individual differences in working memory performance that are not visible at lower loads. If COMT-Met confers greater neural efficiency when working memory is easy, a reasonable prediction is that Met carriers will be better able to cope with increasing demand for neural resources when working memory becomes difficult. To our knowledge, this prediction has thus far gone untested. Here, we tested performance on three working memory tasks. Performance on each task was measured at multiple levels of load/difficulty, including loads more demanding than those used in prior studies. We found no genotype-by-load interactions or main effects of COMT genotype on accuracy or reaction time. Indeed, even testing for performance differences at each load of each task failed to find a single significant effect of COMT genotype. Thus, even if COMT genotype has the effects on prefrontal efficiency that prior work has suggested, such effects may not directly impact high-load working memory ability. The present findings accord with previous evidence that behavioral effects of COMT are small or nonexistent and, more broadly, with a growing consensus that substantial effects on phenotype will not emerge from candidate gene studies. Copyright © 2015 Elsevier Ltd. All rights reserved.
Beckwée, David; Vaes, Peter; Shahabpour, Maryam; Muyldermans, Ronald; Rommers, Nikki; Bautmans, Ivan
2015-12-01
Bone marrow lesions (BMLs) are considered as predictors of pain, disability, and structural progression of knee osteoarthritis. The relationship between knee loading and BMLs is not yet completely understood. To summarize the available evidence regarding the relationship between joint loading and the prevalence and progression of BMLs in the tibiofemoral joint. Meta-analysis. Three databases (PubMed, Web of Science, and The Cochrane Library) were systematically screened for studies encompassing BMLs and changes in knee loading. A methodological quality assessment was conducted, and a meta-analysis computing overall odds ratios (ORs) was performed where possible. A total of 29 studies involving 7641 participants were included. Mechanical loading was categorized as body weight and composition, compartmental load, structural lesion, and physical activity. High compartmental loads and structural lesions increased the risk for BMLs (overall ORs ranging from 1.56 [95% CI, 1.13-2.15] to 8.2 [95% CI, 4.4-15.1]; P = .006). Body weight increased the risk for BMLs to a lesser extent (overall OR, 1.03; 95% CI, 1.01-1.05; P = .007). Contradictory results for the effect of physical activity on BMLs were found. Augmented compartmental loads and structural lesions increased the risk of the presence or progression of BMLs. Body weight increased the risk for BMLs to a lesser extent. Contradictory results for the effect of physical activity on BMLs may be explained by a dose-response relationship, knee alignment, and structural lesions. It has been shown that unloading the knee temporarily may induce beneficial effects on osteoarthritis-related structural changes. Therefore, an early recognition of BMLs in the aging athlete's knee may provide information to counter the onset and aggravation of symptomatic knee osteoarthritis by reducing the knee load. © 2015 The Author(s).
Choi, Seong Wook; Nam, Kyoung Won; Lim, Ki Moo; Shim, Eun Bo; Won, Yong Soon; Woo, Heung Myong; Kwak, Ho Hyun; Noh, Mi Ryoung; Kim, In Young; Park, Sung Min
2014-04-03
When using a pulsatile left ventricular assist device (LVAD), it is important to reduce the cardiac load variations of the native heart because severe cardiac load variations can induce ventricular arrhythmia. In this study, we investigated the effect of counter-pulsation control of the LVAD on the reduction of cardiac load variation. A ventricular electrocardiogram-based counter-pulsation control algorithm for a LVAD was implemented, and the effects of counter-pulsation control of the LVAD on the reduction of the working load variations of the left ventricle were determined in three animal experiments. Deviations of the working load of the left ventricle were reduced by 51.3%, 67.9%, and 71.5% in each case, and the beat-to-beat variation rates in the working load were reduced by 84.8%, 82.7%, and 88.2% in each ease after counter-pulsation control. There were 3 to 12 premature ventricle contractions (PVCs) before counter-pulsation control, but no PVCs were observed during counter-pulsation control. Counter-pulsation control of the pulsatile LVAD can reduce severe cardiac load variations, but the average working load is not markedly affected by application of counter-pulsation control because it is also influenced by temporary cardiac outflow variations. We believe that counter-pulsation control of the LVAD can improve the long-term safety of heart failure patients equipped with LVADs.
Nath, Shekhar; Bodhak, Subhadip; Basu, Bikramjit
2007-10-01
Among various biocompatible polymers, polyethylene based materials have received wider attention because of its excellent stability in body fluid, inertness, and easy formability. Attempts have been made to improve their physical properties (modulus/strength) to enable them to be used as load bearing hard tissue replacement applications. Among such attempts, high density polyethylene (HDPE)-hydroxyapatite (HAp) composite (HAPEX), has already been developed for total hip replacement (THR) acetabular cup and low load bearing bone tissue replacement. In the present work, alumina has been added as a partial replacement of HAp phase to improve the mechanical and tribological properties of the HAPEX composite. In an attempt to assess the suitability of the developed composite in THR application, the tribological properties against steel counterbody under both in air and simulated body fluid (SBF), have been investigated and efforts have been made to understand the wear mechanisms. The fretting wear study indicates the possibility of achieving extremely low COF (Coefficient of Friction approximately 0.09) as well as higher wear resistance (order of 10(-6) mm(3)/N m) with the newly developed composites in SBF. A low wear depth of approximately 4.6-5.3 microm is recorded, irrespective of fretting environment. The implication of the work is that optimal and combined addition of bioactive and bioinert ceramic filler to HDPE can provide a good opportunity to obtain hybrid biocomposites with better combination of physical properties (modulus, hardness) as well as low friction and high wear resistance.
NASA Astrophysics Data System (ADS)
Fanelli, Pierluigi; Biscarini, Chiara; Jannelli, Elio; Ubertini, Filippo; Ubertini, Stefano
2017-02-01
Various mechanical, ocean, aerospace and civil engineering problems involve solid bodies impacting the water surface and often result in complex coupled dynamics, characterized by impulsive loading conditions, high amplitude vibrations and large local deformations. Monitoring in such problems for purposes such as remaining fatigue life estimation and real time damage detection is a technical and scientific challenge of primary concern in this context. Open issues include the need for developing distributed sensing systems able to operate at very high acquisition frequencies, to be utilized to study rapidly varying strain fields, with high resolution and very low noise, while scientific challenges mostly relate to the definition of appropriate signal processing and modeling tools enabling the extraction of useful information from distributed sensing signals. Building on previous work by some of the authors, we propose an enhanced method for real time deformed shape reconstruction using distributed FBG strain measurements in curved bodies subjected to impulsive loading and we establish a new framework for applying this method for structural health monitoring purposes, as the main focus of the work. Experiments are carried out on a cylinder impacting the water at various speeds, proving improved performance in displacement reconstruction of the enhanced method compared to its previous version. A numerical study is then carried out considering the same physical problem with different delamination damages affecting the body. The potential for detecting, localizing and quantifying this damage using the reconstruction algorithm is thoroughly investigated. Overall, the results presented in the paper show the potential of distributed FBG strain measurements for real time structural health monitoring of curved bodies under impulsive hydrodynamic loading, defining damage sensitive features in terms of strain or displacement reconstruction errors at selected locations along the structure.
Kharitonova, Maria; Winter, Warren; Sheridan, Margaret A
2015-09-01
Working memory develops slowly: Even by age 8, children are able to maintain only half the number of items that adults can remember. Neural substrates that support performance on working memory tasks also have a slow developmental trajectory and typically activate to a lesser extent in children, relative to adults. Little is known about why younger participants elicit less neural activation. This may be due to maturational differences, differences in behavioral performance, or both. Here we investigate the neural correlates of working memory capacity in children (ages 5-8) and adults using a visual working memory task with parametrically increasing loads (from one to four items) using fMRI. This task allowed us to estimate working memory capacity limit for each group. We found that both age groups increased the activation of frontoparietal networks with increasing working memory loads, until working memory capacity was reached. Because children's working memory capacity limit was half of that for adults, the plateau occurred at lower loads for children. Had a parametric increase in load not been used, this would have given an impression of less activation overall and less load-dependent activation for children relative to adults. Our findings suggest that young children and adults recruit similar frontoparietal networks at working memory loads that do not exceed capacity and highlight the need to consider behavioral performance differences when interpreting developmental differences in neural activation.
Can physical activity improve peak bone mass?
Specker, Bonny; Minett, Maggie
2013-09-01
The pediatric origin of osteoporosis has led many investigators to focus on determining factors that influence bone gain during growth and methods for optimizing this gain. Bone responds to bone loading activities by increasing mass or size. Overall, pediatric studies have found a positive effect of bone loading on bone size and accrual, but the types of loads necessary for a bone response have only recently been investigated in human studies. Findings indicate that responses vary by sex, maturational status, and are site-specific. Estrogen status, body composition, and nutritional status also may influence the bone response to loading. Despite the complex interrelationships among these various factors, it is prudent to conclude that increased physical activity throughout life is likely to optimize bone health.
Zhang, Fei-ruo; Wang, Sheng; He, Li-hua; Zhang, Ying; Wu, Shan-shan; Li, Jing-yun; Hu, Guang-yi; Ye, Kang-ping
2011-03-01
To study neck and shoulder work-related muscle fatigue of female sewing machine operators. 18 health female sewing machine operators without musculoskeletal disorders work in Beijing garment industry factory as volunteers in participate of this study. The maximal voluntary contraction (MVC) and 20% MVC of bilateral upper trapezium and cervical erectors spinae was tested before sewing operations, then the whole 20 time windows (1 time window = 10 min) sewing machine operations was monitored and the surface electromyography (sEMG) signals simultaneously was recorded after monitoring the 20%MVC was tested. Use amplitude analysis method to reduction recorded EMG signals. During work, the median load for the left cervical erector spinae (LCES), right cervical erector spinae (RCES), left upper trapezium (LUT) and right upper trapezium (RUT) respectively was 6.78 ± 1.05, 6.94 ± 1.12, 5.68 ± 2.56 and 6.47 ± 3.22, work load of right is higher than the left; static load analysis indicated the value of RMS(20%MVC) before work was higher than that value after work, the increase of right CES and UT RMS(20%MVC) was more; the largest 20%MVE of bilateral CES occurred at 20th time window, and that of bilateral UT happened at 16th. The work load of female sewing machine operators is sustained "static" load, and work load of right neck-shoulder is higher than left, right neck-shoulder muscle is more fatigable and much serious once fatigued.
Castellano, Julen; Puente, Asier; Echeazarra, Ibon; Usabiaga, Oidui; Casamichana, David
2016-01-01
The aim of the present study is to analyse the influence of different large-sided games (LSGs) on the physical and physiological variables in under-12s (U12) and -13s (U13) soccer players. The effects of the combination of different number of players per team, 7, 9, and 11 (P7, P9, and P11, respectively) with three relative pitch areas, 100, 200, and 300 m(2) (A100, A200, and A300, respectively), were analysed in this study. The variables analysed were: 1) global indicator such as total distance (TD); work:rest ratio (W:R); player-load (PL) and maximal speed (Vmax); 2) heart rate (HR) mean and time spent in different intensity zones of HR (<75%, 75-84%, 84-90% and >90%), and; 3) five absolute (<8, 8-13, 13-16 and >16 Km h(-1)) and three relative speed categories (<40%, 40-60% and >60% Vmax). The results support the theory that a change in format (player number and pitch dimensions) affects no similarly in the two players categories. Although it can seem that U13 players are more demanded in this kind of LSG, when the work load is assessed from a relative point of view, great pitch dimensions and/or high number of player per team are involved in the training task to the U12 players. The results of this study could alert to the coaches to avoid some types of LSGs for the U12 players such as: P11 played in A100, A200 or A300, P9 played in A200 or A300 and P7 played in A300 due to that U13>U12 in several physical and physiological variables (W:R, time spent in 84-90%HRmax, distance in 8-13 and 13-16 Km h(-1) and time spent in 40-60%Vmax). These results may help youth soccer coaches to plan the progressive introduction of LSGs so that task demands are adapted to the physiological and physical development of participants.
NASA Astrophysics Data System (ADS)
Kang, Hongpu; Li, Jianzhong; Yang, Jinghe; Gao, Fuqiang
2017-02-01
In underground coal mining, high abutment loads caused by the extraction of coal can be a major contributor to many rock mechanic issues. In this paper, a large-scale physical modeling of a 2.6 × 2.0 × 1.0 m entry roof has been conducted to investigate the fundamentals of the fracture mechanics of entry roof strata subjected to high abutment loads. Two different types of roof, massive roof and laminated roof, are considered. Rock bolt system has been taken into consideration. A distinct element analyses based on the physical modeling conditions have been performed, and the results are compared with the physical results. The physical and numerical models suggest that under the condition of high abutment loads, the massive roof and the laminated roof fail in a similar pattern which is characterized as vertical tensile fracturing in the middle of the roof and inclined shear fracturing initiated at the roof and rib intersections and propagated deeper into the roof. Both the massive roof and the laminated roof collapse in a shear sliding mode shortly after shear fractures are observed from the roof surface. It is found that shear sliding is a combination of tensile cracking of intact rock and sliding on bedding planes and cross joints. Shear sliding occurs when the abutment load is much less than the compressive strength of roof.
Romaratezabala, Estibaliz; Nakamura, Fábio Yuzo; Castillo, Daniel; Gorostegi-Anduaga, Ilargi; Yanci, Javier
2018-01-01
The purpose of the study was to analyse the effect of two warm-up protocols of different duration on physical performance, perceived load and perception of being ready for a match in handball players. Eighteen handball players were randomly divided into two groups (Wup 34min , warm-up protocol of 34 min, Wup 17min , warm-up protocol of 17 min). Before and after the warm-up protocols, they performed a battery of physical tests and recorded their perception of feeling ready for a match. At the end of the warm-up protocols, all the players evaluated their differentiated perceived effort (dRPE). The results showed that neither of the protocols significantly modified (p > 0.05) the players' physical performance. However, the Wup 34min group showed higher values in the differentiated warm-up perceived load (dRPE-WL) (p < 0.01, TE = 0.97-1.27, high) than the Wup 17min group. The players with a greater perceived muscular load (RPE MUSC ) experienced a greater decrease in their acceleration capacity (r = 0.48-0.49, p < 0.05). In spite of the fact that neither of the warm-up protocols significantly modified the players' physical performance, a greater perceived muscular load may cause a greater decrease in acceleration capacity.
Characterization of Inductive loop coupling in a Cyclotron Dee Structure
NASA Astrophysics Data System (ADS)
Carroll, Lewis
Many of today's low to medium-energy cyclotrons apply RF power to the resonator structure (the dees) by inductive loop coupling through a feed-line driven by an RF transmitter employing a triode or tetrode power tube. The transmitter's output network transforms the tube's optimum load line (typically a few thousand ohms) down to Z0, typically 50 ohms. But the load-line is not a physical resistance, so one would not expect to see 50 ohms when looking back toward the transmitter. Moreover, if both the resonator's input and the transmitter's output are matched to Z0, then the coupled or working Q of the resonator is reduced to half that of the uncoupled Q, implying that half the power is being dissipated in the transmitter's output resistance- an inefficient and expensive solution for a high power RF application. More power is available if the transmitter's reverse-impedance is not matched to Z0, but this may result in misalignment between the frequency for correct forward match at the loop, versus the frequency for maximum power in the resonator. The misalignment can be eliminated, and the working Q maximized, by choosing the appropriate length of feed-line between the non-matched transmitter output and the matched resonator's input. In addition, the transmitter's output impedance may be complex, comprising resistance plus reactance, requiring a further process and means of measuring the output impedance so that an additional compensating length of feed-line can be incorporated. But a wrong choice of overall feed-line length- even though correctly load-matched at the resonator's operating frequency- can result in a curious degenerate condition, where the resonator's working Q appears to collapse, and the potential for transmitter overload increases substantially: a condition to be avoided!
Grissmann, Sebastian; Faller, Josef; Scharinger, Christian; Spüler, Martin; Gerjets, Peter
2017-01-01
Most brain-based measures of the electroencephalogram (EEG) are used in highly controlled lab environments and only focus on narrow mental states (e.g., working memory load). However, we assume that outside the lab complex multidimensional mental states are evoked. This could potentially create interference between EEG signatures used for identification of specific mental states. In this study, we aimed to investigate more realistic conditions and therefore induced a combination of working memory load and affective valence to reveal potential interferences in EEG measures. To induce changes in working memory load and affective valence, we used a paradigm which combines an N-back task (for working memory load manipulation) with a standard method to induce affect (affective pictures taken from the International Affective Picture System (IAPS) database). Subjective ratings showed that the experimental task was successful in inducing working memory load as well as affective valence. Additionally, performance measures were analyzed and it was found that behavioral performance decreased with increasing workload as well as negative valence, showing that affective valence can have an effect on cognitive processing. These findings are supported by changes in frontal theta and parietal alpha power, parameters used for measuring of working memory load in the EEG. However, these EEG measures are influenced by the negative valence condition as well and thereby show that detection of working memory load is sensitive to affective contexts. Unexpectedly, we did not find any effects for EEG measures typically used for affective valence detection (Frontal Alpha Asymmetry (FAA)). Therefore we assume that the FAA measure might not be usable if cognitive workload is induced simultaneously. We conclude that future studies should account for potential context-specifity of EEG measures. PMID:29311875
Grissmann, Sebastian; Faller, Josef; Scharinger, Christian; Spüler, Martin; Gerjets, Peter
2017-01-01
Most brain-based measures of the electroencephalogram (EEG) are used in highly controlled lab environments and only focus on narrow mental states (e.g., working memory load). However, we assume that outside the lab complex multidimensional mental states are evoked. This could potentially create interference between EEG signatures used for identification of specific mental states. In this study, we aimed to investigate more realistic conditions and therefore induced a combination of working memory load and affective valence to reveal potential interferences in EEG measures. To induce changes in working memory load and affective valence, we used a paradigm which combines an N-back task (for working memory load manipulation) with a standard method to induce affect (affective pictures taken from the International Affective Picture System (IAPS) database). Subjective ratings showed that the experimental task was successful in inducing working memory load as well as affective valence. Additionally, performance measures were analyzed and it was found that behavioral performance decreased with increasing workload as well as negative valence, showing that affective valence can have an effect on cognitive processing. These findings are supported by changes in frontal theta and parietal alpha power, parameters used for measuring of working memory load in the EEG. However, these EEG measures are influenced by the negative valence condition as well and thereby show that detection of working memory load is sensitive to affective contexts. Unexpectedly, we did not find any effects for EEG measures typically used for affective valence detection (Frontal Alpha Asymmetry (FAA)). Therefore we assume that the FAA measure might not be usable if cognitive workload is induced simultaneously. We conclude that future studies should account for potential context-specifity of EEG measures.
Quantification of Daily Physical Activity
NASA Technical Reports Server (NTRS)
Whalen, Robert; Breit, Greg; Quintana, Jason
1994-01-01
The influence of physical activity on the maintenance and adaptation of musculoskeletal tissue is difficult to assess. Cumulative musculoskeletal loading is hard to quantify and the attributes of the daily tissue loading history affecting bone metabolism have not been completely identified. By monitoring the vertical component of the daily ground reaction force (GRFz), we have an indirect measure of cumulative daily lower limb musculoskeletal loading to correlate with bone density and structure. The objective of this research is to develop instrumentation and methods of analysis to quantify activity level in terms of the daily history of ground reaction forces.
[Attention, repetitive works, fatigue and stress].
Tomei, G; Cinti, M E; Cerratti, D; Fioravanti, M
2006-01-01
Repetitive work in occupational settings often requires a combination of mental and physical demands, but few studies were conducted concerning the relationship between attention and repetitive work. In attentive and cognitive tasks, it is common to observe effort and fatigue without the presence of those neuromuscular modifications that would justify the use of these terms. Therefore, we can talk about mental fatigue in those cases in which it is observed the exhaustion of the necessary resources for the execution of a job that doesn't demand the employment of neuromuscular apparatus. Scientific literature about this argument consists of experimental studies which aim to estimate at what extent attentive demands exspecially cognitive demands can interact with physical ones which are peculiarities of repetitive tasks. Work characterized by the maintenance of high levels of performance for a long time, produce cognitive effort with high level of vigilance, selective attention, decisional ability, automated control mechanisms, such as "eye-hand", and may contribute to the fatigue. Indeed, fatigue plays a important role in a working context since, it may interfere with the work itself by reducing the worker's efficiency and performance and if excessive and extended, it may alter the subject's psycho-physical condition and induce different pathologies. Repetitive work can contribute to the increasing of muscular fatigue by inducing mental fatigue: for example tasks which require high vigilance but low neuromuscular work, may induce a sense of effort and fatigue and cognitive factors and mental stress may cause muscular fatigue. Several intrinsic job factors, including repetitive works, may act as stressors and they can cause mental and physical symptoms such as anxiety, depression and somatic diseases. The European Community has often emphasized the pathogenic value of stress and fatigue with their high social and individual costs. For this purpose, it is opportune to consider the norm UNI EN ISO 10075, which points out the necessity to consider the human component, in term of mental load which implies not only the cognitive component but also the whole psychical sphere of the subject. Training intended like a sort of learning of specific modalities, supplies workers with the necessary instruments for a correct and more aware management of the peculiarities of working activity, contributing to the reduction of fatigue and stress deriving from the job.
Time- & Load-Dependence of Triboelectric Effect.
Pan, Shuaihang; Yin, Nian; Zhang, Zhinan
2018-02-06
Time- and load-dependent friction behavior is considered as important for a long time, due to its time-evolution and force-driving characteristics. However, its electronic behavior, mainly considered in triboelectric effect, has almost never been given the full attention and analyses from the above point of view. In this paper, by experimenting with fcc-latticed aluminum and copper friction pairs, the mechanical and electronic behaviors of friction contacts are correlated by time and load analyses, and the behind physical understanding is provided. Most importantly, the difference of "response lag" in force and electricity is discussed, the extreme points of coefficient of friction with the increasing normal loads are observed and explained with the surface properties and dynamical behaviors (i.e. wear), and the micro and macro theories linking tribo-electricity to normal load and wear (i.e. the physical explanation between coupled electrical and mechanical phenomena) are successfully developed and tested.
NASA Astrophysics Data System (ADS)
Li, Yuting; Wang, Tianyi; Wang, Jing; Jiang, Tongying; Cheng, Gang; Wang, Siling
2011-04-01
The purpose of this study was to develop carboxyl multi-wall carbon nanotubes (MWNTs) and unmodified MWNTs loaded with a poorly water-soluble drug, intended to improve the drug loading capacity, dissolubility and study the drug-loading mechanism. MWNTs were modified with a carboxyl group through the acid treatment. MWNTs as well as the resulting functionalized MWNTs were investigated as scaffold for loading the model drug, Carvedilol (CAR), using three different methods (the fusion method, the incipient wetness impregnation method, and the solvent method). The effects of different pore size, specific surface area and physical state were systematically studied using scanning electron microscopy (SEM), thermogravimetric analysis (TGA), Fourier transformation infrared spectroscopy (FT-IR), differential scanning calorimetry (DSC), nitrogen adsorption, X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS). The functional MWNTs allowed a higher drug loading than the unmodified preparations. The methods used to load the drug had a marked effect on the drug-loading, dissolution, and physical state of the drug as well as its distribution. In addition, the solubility of the drug was increased when carried by both MWNTs and functional MWNTs, and this might help to improve the bioavailability.
Encapsulation of Polymethoxyflavones in Citrus Oil Emulsion-Based Delivery Systems.
Yang, Ying; Zhao, Chengying; Chen, Jingjing; Tian, Guifang; McClements, David Julian; Xiao, Hang; Zheng, Jinkai
2017-03-01
The purpose of this work was to elucidate the effects of citrus oil type on polymethoxyflavone (PMF) solubility and on the physicochemical properties of PMF-loaded emulsion-based delivery systems. Citrus oils were extracted from mandarin, orange, sweet orange, and bergamot. The major constituents were determined by GC/MS: sweet orange oil (97.4% d-limonene); mandarin oil (72.4% d-limonene); orange oil (67.2% d-limonene); and bergamot oil (34.6% linalyl acetate and 25.3% d-limonene). PMF-loaded emulsions were fabricated using 10% oil phase (containing 0.1% w/v nobiletin or tangeretin) and 90% aqueous phase (containing 1% w/v Tween 80) using high-pressure homogenization. Delivery systems prepared using mandarin oil had the largest mean droplet diameters (386 or 400 nm), followed by orange oil (338 or 390 nm), bergamot oil (129 or 133 nm), and sweet orange oil (122 or 126 nm) for nobiletin- or tangeretin-loaded emulsions, respectively. The optical clarity of the emulsions increased with decreasing droplet size due to reduced light scattering. The viscosities of the emulsions (with or without PMFs) were similar (1.3 to 1.4 mPa·s), despite appreciable differences in oil phase viscosity. The loading capacity and encapsulation efficiency of the emulsions depended on carrier oil type, with bergamot oil giving the highest loading capacity. In summary, differences in the composition and physical characteristics of citrus oils led to PMF-loaded emulsions with different encapsulation and physicochemical characteristics. These results will facilitate the rational design of emulsion-based delivery systems for encapsulation of PMFs and other nutraceuticals in functional foods and beverages.
NASA Astrophysics Data System (ADS)
Chen, Mingdong; Zhao, Dingxuan
2017-01-01
Considering the disadvantage of higher throttling loss for the open-circuit hydrostatic transmission at present, a novel gravitational potential energy regeneration system (GPERS) of the boom of hydraulic excavator, namely the closed-circuit GPERS, is proposed in this paper. The closed-circuit GPERS is based on a closed-circuit hydrostatic transmission and adopts a hydraulic accumulator as main energy storage element fabricated in novel configuration to recover the entire gravitational potential energy of the boom of hydraulic excavator. The matching parameter and control system design are carried out for the proposed system, and the system is modeled based on its physical attributes. Simulation and experiments are performed to validate the employed mathematical models, and then, the velocity and the pressure performance of system are analyzed. It is observed that the closed-circuit GPERS shows better velocity control of the boom and response characteristics. After that, the average working efficiency of the closed-circuit GPERS of boom is estimated under different load conditions. The results indicate that the proposed system is highly effective and that the average working efficiency in different load conditions varied from 60% to 68.2% for the experiment platform.
The influence of package size and flute type of corrugated boxes on load bridging in unit loads
Jonghun Park; Laszlo Horvath; Marshall S. White; Samantha Phanthanousy; Philip Araman; Robert J. Bush
2017-01-01
Shipping pallets often are designed with the assumption that the payload carried is flexible and uniformly distributed on the pallet surface. However, packages on the pallet can act as a series of discrete loads, and the physical interactions among the packages can add stiffness to the pallet/load combination. The term âload bridgingâ has been used to describe this...
Can 'loss and damage' carry the load?
Verchick, Robert R M
2018-05-13
Even assuming a heroic rush towards carbon reduction and adaptation, some regions of the world will be hammered hard by climate impacts. Thus, a global consensus now sees the need for a supplemental plan to deal with the kind of harms that cannot be avoided-what Parties call 'loss and damage'. For a loss-and-damage plan to work, it must be capable of carrying the load, the load being whatever minimal standards that morality and political consensus require. But if residual risk climbs too high, it will fall short of even the most basic expectations. The Paris Agreement calls for holding the rise in global average temperature to 'well below 2°C above pre-industrial levels', while working to limit the increase to 1.5°C. How much difference is in that half-degree? From the point of view of residual risk, quite a lot. According to a 2016 study published by the European Geosciences Union, a jump from 1.5°C to 2°C could produce outsize impacts, particularly in tropical latitudes. That difference could mark the line between a plan that is politically and morally defensible and one that is not. At the very least, the difference is enough to inform the design and expectations of any future plan.This article is part of the theme issue 'The Paris Agreement: understanding the physical and social challenges for a warming world of 1.5°C above pre-industrial levels'. © 2018 The Author(s).
Can `loss and damage' carry the load?
NASA Astrophysics Data System (ADS)
Verchick, Robert R. M.
2018-05-01
Even assuming a heroic rush towards carbon reduction and adaptation, some regions of the world will be hammered hard by climate impacts. Thus, a global consensus now sees the need for a supplemental plan to deal with the kind of harms that cannot be avoided-what Parties call `loss and damage'. For a loss-and-damage plan to work, it must be capable of carrying the load, the load being whatever minimal standards that morality and political consensus require. But if residual risk climbs too high, it will fall short of even the most basic expectations. The Paris Agreement calls for holding the rise in global average temperature to `well below 2°C above pre-industrial levels', while working to limit the increase to 1.5°C. How much difference is in that half-degree? From the point of view of residual risk, quite a lot. According to a 2016 study published by the European Geosciences Union, a jump from 1.5°C to 2°C could produce outsize impacts, particularly in tropical latitudes. That difference could mark the line between a plan that is politically and morally defensible and one that is not. At the very least, the difference is enough to inform the design and expectations of any future plan. This article is part of the theme issue `The Paris Agreement: understanding the physical and social challenges for a warming world of 1.5°C above pre-industrial levels'.
ERIC Educational Resources Information Center
de Fockert, Jan W.; Bremner, Andrew J.
2011-01-01
An unexpected stimulus often remains unnoticed if attention is focused elsewhere. This inattentional blindness has been shown to be increased under conditions of high memory load. Here we show that increasing working memory load can also have the opposite effect of reducing inattentional blindness (i.e., improving stimulus detection) if stimulus…
Allostatic Load and Effort-Reward Imbalance: Associations over the Working-Career
Coronado, José Ignacio Cuitún; Chandola, Tarani; Steptoe, Andrew
2018-01-01
Although associations between work stressors and stress-related biomarkers have been reported in cross-sectional studies, the use of single time measurements of work stressors could be one of the reasons for inconsistent associations. This study examines whether repeated reports of work stress towards the end of the working career predicts allostatic load, a measure of chronic stress related physiological processes. Data from waves 2 to 6 of the English Longitudinal Study of Ageing (ELSA) were analysed, with a main analytical sample of 2663 older adults (aged 50+) who had at least one measurement of effort-reward imbalance between waves 2–6 and a measurement of allostatic load at wave 6. Cumulative work stress over waves 2–6 were measured by the effort-reward imbalance model. ELSA respondents who had reported two or more occasions of imbalance had a higher (0.3) estimate of the allostatic load index than those who did not report any imbalance, controlling for a range of health and socio-demographic factors, as well as allostatic load at baseline. More recent reports of imbalance were significantly associated with a higher allostatic load index, whereas reports of imbalance from earlier waves of ELSA were not. The accumulation of work related stressors could have adverse effects on chronic stress biological processes. PMID:29364177
Allostatic Load and Effort-Reward Imbalance: Associations over the Working-Career.
Coronado, José Ignacio Cuitún; Chandola, Tarani; Steptoe, Andrew
2018-01-24
Although associations between work stressors and stress-related biomarkers have been reported in cross-sectional studies, the use of single time measurements of work stressors could be one of the reasons for inconsistent associations. This study examines whether repeated reports of work stress towards the end of the working career predicts allostatic load, a measure of chronic stress related physiological processes. Data from waves 2 to 6 of the English Longitudinal Study of Ageing (ELSA) were analysed, with a main analytical sample of 2663 older adults (aged 50+) who had at least one measurement of effort-reward imbalance between waves 2-6 and a measurement of allostatic load at wave 6. Cumulative work stress over waves 2-6 were measured by the effort-reward imbalance model. ELSA respondents who had reported two or more occasions of imbalance had a higher (0.3) estimate of the allostatic load index than those who did not report any imbalance, controlling for a range of health and socio-demographic factors, as well as allostatic load at baseline. More recent reports of imbalance were significantly associated with a higher allostatic load index, whereas reports of imbalance from earlier waves of ELSA were not. The accumulation of work related stressors could have adverse effects on chronic stress biological processes.
[Job stress and well-being of care providers: development of a standardized survey instrument].
Kivimäki, M; Lindström, K
1992-01-01
The main aim was to develop a standardized survey instrument for measuring job stress and well-being in hospital settings. The actual study group consisted of 349 workers from medical bed wards, first aid unit wards and bed wards for gynecology and obstetrics in a middle-sized hospital in the Helsinki region. Based on the factor analysis of separate questions, the following content areas were chosen for the job stressor scales: haste at work, problems in interpersonal relations at work, problems in occupational collaboration with others, too much responsibility, safety and health risks, lack of appreciation, troublesome patients, and lack of equipment and resources. Content areas for well-being scales and items were general job satisfaction, strain symptoms, perceived mental and physical work load. The reference values of the questionnaire and reliabilities for the scales were calculated. The application and further development of the questionnaire was discussed.
Ergonomics analyses of five joineries located in Florianópolis-SC, using the LEST Method.
Vergara, Lizandra Lupi Garcia; Garcia, Carolina Schwinden; Miranda, Felipe Vergara
2012-01-01
Considering the goal of Ergonomic Work Analysis to establish, from the point of view of workers, safe, healthy, comfortable and efficient environments, this study propose to analyze the work situation of machine operators at five joineries from Florianópolis-SC. For this, it was applied the LEST Method to evaluate the task made by the operators, considering the physical, cognitive and organizational work environment. As results, it was identified the main ergonomics problems of these workstations, presenting an ergonomic diagnosis and their implications on health and safety of workers. As result, it was concluded that the main ergonomics problems at joineries are related with noise, with constant load of weight and with the postures taken. Besides these problems, others were diagnosed, for example, the pressure for workers to comply strictly the task stipulated and also the poor training and capacity of workers.
Amin, N A; Quek, K F; Oxley, J A; Noah, R M; Nordin, R
2015-10-01
The Job Content Questionnaire (M-JCQ) is an established self-reported instrument used across the world to measure the work dimensions based on the Karasek's demand-control-support model. To evaluate the psychometrics properties of the Malay version of M-JCQ among nurses in Malaysia. This cross-sectional study was carried out on nurses working in 4 public hospitals in Klang Valley area, Malaysia. M-JCQ was used to assess the perceived psychosocial stressors and physical demands of nurses at their workplaces. Construct validity of the questionnaire was examined using exploratory factor analysis (EFA). Cronbach's α values were used to estimate the reliability (internal consistency) of the M-JCQ. EFA showed that 34 selected items were loaded in 4 factors. Except for psychological job demand (Cronbach's α 0.51), the remaining 3 α values for 3 subscales (job control, social support, and physical demand) were greater than 0.70, indicating acceptable internal consistency. However, an item was excluded due to poor item-total correlation (r<0.3). The final M-JCQ was consisted of 33 items. The M-JCQ is a reliable and valid instrument to measure psychosocial and physical stressors in the workplace of public hospital nurses in Malaysia.
Essential oil-loaded lipid nanoparticles for wound healing.
Saporito, Francesca; Sandri, Giuseppina; Bonferoni, Maria Cristina; Rossi, Silvia; Boselli, Cinzia; Icaro Cornaglia, Antonia; Mannucci, Barbara; Grisoli, Pietro; Vigani, Barbara; Ferrari, Franca
2018-01-01
Chronic wounds and severe burns are diseases responsible for severe morbidity and even death. Wound repair is a crucial process and tissue regeneration enhancement and infection prevention are key factors to minimize pain, discomfort, and scar formation. The aim of this work was the development of lipid nanoparticles (solid lipid nanoparticles and nanostructured lipid carriers [NLC]), to be loaded with eucalyptus or rosemary essential oils and to be used, as medical devices, to enhance healing of skin wounds. Lipid nanoparticles were based on natural lipids: cocoa butter, as solid lipid, and olive oil or sesame oil, as liquid lipids. Lecithin was chosen as surfactant to stabilize nanoparticles and to prevent their aggregation. The systems were prepared by high shear homogenization followed by ultrasound application. Nanoparticles were characterized for physical-chemical properties, bioadhesion, cytocompatibility, in vitro proliferation enhancement, and wound healing properties toward normal human dermal fibroblasts. Antimicrobial activity of nanoparticles was evaluated against two reference microbial strains, one of Staphylococcus aureus , the other of Streptococcus pyogenes . Finally, the capability of nanoparticles to promote wound healing in vivo was evaluated on a rat burn model. NLC based on olive oil and loaded with eucalyptus oil showed appropriate physical-chemical properties, good bioadhesion, cytocompatibility, in vitro proliferation enhancement, and wound healing properties toward fibroblasts, associated to antimicrobial properties. Moreover, the in vivo results evidenced the capability of these NLC to enhance the healing process. Olive oil, which is characterized by a high content of oleic acid, proved to exert a synergic effect with eucalyptus oil with respect to antimicrobial activity and wound repair promotion.
Interaction of laser radiation with plasma under the MG external magnetic field
NASA Astrophysics Data System (ADS)
Ivanov, V. V.; Maximov, A. V.; Betti, R.; Sawada, H.; Sentoku, Y.
2016-10-01
Strong magnetic fields play an important role in many physical processes relevant to astrophysical events and fusion research. Laser produced plasma in the MG external magnetic field was studied at the 1 MA pulsed power generator coupled with the laser operated in ns and ps regimes. Rod loads and coils under 1 MA current were used to produce a magnetic field of 2-3 MG. In one type of experiments, a 0.8 ns laser pulse was focused on the load surface with intensity of 3x1015 W/cm2. Laser diagnostics showed that the laser produced plasma expands in the transversal magnetic field and forms a thin plasma disc with a typical diameter of 3-7 mm and thickness of 0.2-0.4 mm. A magnetosonic-type wave was observed in the plasma disc and on the surface of the rod load. The plasma disc expands radially across the magnetic field with a velocity of the order of the magnetosonic velocity. Physical mechanisms involved in the formation of the plasma disc may be relevant to the generation of plasma loops in sun flares. Other experiments, with a 0.4 ps laser pulse were carried for investigation of the isochoric heating of plasma with fast electrons confined by the strong magnetic field. The laser beam was focused by the parabola mirror on a solid target in the magnetic field of the coil. Work was supported by the DOE Grant DE-SC0008824 and DOE/NNSA UNR Grant DE-FC52-06NA27616.
Cyber-physical experiments on the efficiency of swimming protocols
NASA Astrophysics Data System (ADS)
Wei, Nathaniel; Floryan, Daniel; van Buren, Tyler; Smits, Alexander
2016-11-01
We present results from experiments on a biologically inspired cyber-physical system, composed of a two-dimensional heaving and pitching rigid airfoil attached to a six component load cell, mounted to a traverse that can move along a water channel. A feedback controller, influenced by the apparatus of Mackowski and Williamson, introduces the effects of a fictional drag force specified by a virtual body profile and drives the traverse accordingly. Free-swimming protocols using the force-feedback system are compared with similar motions on a motionless traverse. The propulsive efficiency of burst-and-coast kinematics is also considered. Of particular interest are (1) the implementation of the cyber-physical control system with respect to the accessible experimental parameter space, (2) the impact of force-based streamwise actuation on experimental data, and (3) the effects of burst-and-coast motions on propulsive efficiency. The work was supported by the Office of Naval Research (ONR) under MURI Grant N00014-14-1-0533.
Zhang, Tan; Chen, Ang
2017-01-01
Based on the job demands-resources model, the study developed and validated an instrument that measures physical education teachers' job demands-resources perception. Expert review established content validity with the average item rating of 3.6/5.0. Construct validity and reliability were determined with a teacher sample ( n = 397). Exploratory factor analysis established a five-dimension construct structure matching the theoretical construct deliberated in the literature. The composite reliability scores for the five dimensions range from .68 to .83. Validity coefficients (intraclass correlational coefficients) are .69 for job resources items and .82 for job demands items. Inter-scale correlational coefficients range from -.32 to .47. Confirmatory factor analysis confirmed the construct validity with high dimensional factor loadings (ranging from .47 to .84 for job resources scale and from .50 to .85 for job demands scale) and adequate model fit indexes (root mean square error of approximation = .06). The instrument provides a tool to measure physical education teachers' perception of their working environment.
Zhang, Tan; Chen, Ang
2017-01-01
Based on the job demands–resources model, the study developed and validated an instrument that measures physical education teachers’ job demands–resources perception. Expert review established content validity with the average item rating of 3.6/5.0. Construct validity and reliability were determined with a teacher sample (n = 397). Exploratory factor analysis established a five-dimension construct structure matching the theoretical construct deliberated in the literature. The composite reliability scores for the five dimensions range from .68 to .83. Validity coefficients (intraclass correlational coefficients) are .69 for job resources items and .82 for job demands items. Inter-scale correlational coefficients range from −.32 to .47. Confirmatory factor analysis confirmed the construct validity with high dimensional factor loadings (ranging from .47 to .84 for job resources scale and from .50 to .85 for job demands scale) and adequate model fit indexes (root mean square error of approximation = .06). The instrument provides a tool to measure physical education teachers’ perception of their working environment. PMID:29200808
[Occupational microclimate. Results and prospects of research].
Afanas'eva, R F; Bessonova, N A; Burmistrova, O V; Burmistrov, V M; Losik, T K
2013-01-01
The article covers results of studies conducted over last 15 years and aimed to elaboration of requirements to integral parameters of microclimate at workplace, its evaluation and regulation, prophylactic measures against body overcooling and overheating. The authors present methods to evaluate combined effects of physical factors (noise, vibration, microclimate) and to assess microclimate with consideration of factors determining body thermal load (energy expenditure, duration of stay at workplace, heat insulation of clothes and thermo-physical parameters of its materials). Mathematic models of forecasting cold and heat stress are presented, as well as requirements to heat insulation for individual protective means against cold and methods to calculate it. Regimens of work in heating and cooling conditions are specified. The authors set directions for further studies to define regulation requirements to microclimate on basis of studied patterns of body heat state formation, its evaluation criteria, epidemiologic studies results, specified prophylactic measures against overheating and overcooling with consideration of adaptation, sex, thermo-physical characteristics of individual protective means (special clothes, footwear, gauntlets, headwear).
Jurewicz, Joanna; Hanke, Wojciech; Makowiec-Dabrowska, Teresa
2008-01-01
There are two major potential hazards typical of work in greenhouses: hard physical work or exposure to pesticides. The aim of the study was to investigate whether the work in greenhouse during pregnancy have an adverse effect on its outcome (preterm delivery, spontaneous abortion and birth defects). The study was performed in a group of 460 women employed in 14 greenhouses involved in growing vegetables and flowers. The rate of spontaneous abortions was much elbeit insignificantly higher in the women working in greenhouses during pregnancy than in those employed out of them; that applied mostly to the women performing light jobs in greenhouses. An increased risk of preterm delivery and spontaneous abortion was also observed in women performing greenhouse light jobs. No significantly increased risk of birth defects was observed in children born to women working in greenhouses. Neither was there any relationship between exposure to RD or ED pesticides exposure--and the occurrence of preterm delivery, spontaneous abortion and birth defects. No higher risk of pathological pregnancy that could be associated with hard physical work and pesticide exposure was observed. This may result from the fact that women themselves select an appropriate kind of job during pregnancy and a possible removal of women with pathological pregnancy from jobs involving pesticide exposure, as well as from the promotion of biological protection. The greenhouse workers should be aware of the two typical hazards found in greenhouses (hard work and exposure to pesticides) and their potential negative effects on the reproduction. The results of this study warrant the need for further study of the effect of pesticide exposure and work load on the pregnancy outcome.
Meerding, W J; IJzelenberg, W; Koopmanschap, M A; Severens, J L; Burdorf, A
2005-05-01
To assess the feasibility and validity of two instruments for the measurement of health-related productivity loss at work. A cross-sectional study was conducted in two occupational populations with a high prevalence of health problems: industrial workers (n=388) and construction workers (n=182). We collected information on self-reported productivity during the previous 2 weeks and during the last work day with the Health and Labor Questionnaire (HLQ) and the Quantity and Quality instrument (QQ), with added data on job characteristics, general health, presence of musculoskeletal complaints, sick leave, and health-care consumption. For construction workers, we validated self-reported productivity with objective information on daily work output from 19 work site observations. About half the workers with health problems on the last working day reported reduced work productivity (QQ), or 10.7% of all industrial workers and 11.8% of all construction workers, resulting in a mean loss of 2.0 hr/day per worker with reduced work productivity. The proportion of workers with reduced productivity was significantly lower on the HLQ: 5.3% of industrial workers and 6.5% of construction workers. Reduced work productivity on the HLQ and the QQ was significantly associated with musculoskeletal complaints, worse physical, mental and general health, and recent absenteeism. The QQ and HLQ questionnaires demonstrated poor agreement on the reporting of reduced productivity. Self-reported productivity on the QQ correlated significantly with objective work output (r=.48). Health problems may lead to considerable sickness presenteeism. The QQ measurement instrument is better understandable, and more feasible for jobs with low opportunities for catching up on backlogs.
[Occupational stress effects on work ability in chemistry workers].
Yang, Huifang; Wang, Mianzhen; Wang, Zhiming; Lan, Yajia
2004-03-01
Investigating the status of work ability and occupational stress in 1030 chemistry workers at levels of chemical materials and explore their relationship and influence factors (481 workers of study group, 549 workers of control group). Work ability and occupational stress were measured with the work ability index (WAI) and occupational stress questionnaire (OSQ). The risk factors of work ability decline were evaluated. WAI and OSQ scores scores are significantly different between study group and control group (P < 0.01), and work ability correlated inversely with occupational stress (P < 0.01). The WAI scores are reducing with a higher of the OSQ. The work ability of chemistry-workers became lower with the increasing of age. Variables that influence work ability included the factors of disorder of musculoskeletal function (OR = 2.884), assessment of the current health (OR = 2.651), the diseases (OR = 2.498), emotion status (OR = 2.407), physical load (OR = 1.254) and lack of exercise (OR = 1.956). The stress levels and stress factors had affected work ability in chemistry-workers, and it was suggested that the findings could be helpful for the measures protecting and promoting of work ability on the health of workers.
Working memory regulates trait anxiety-related threat processing biases.
Booth, Robert W; Mackintosh, Bundy; Sharma, Dinkar
2017-06-01
High trait anxious individuals tend to show biased processing of threat. Correlational evidence suggests that executive control could be used to regulate such threat-processing. On this basis, we hypothesized that trait anxiety-related cognitive biases regarding threat should be exaggerated when executive control is experimentally impaired by loading working memory. In Study 1, 68 undergraduates read ambiguous vignettes under high and low working memory load; later, their interpretations of these vignettes were assessed via a recognition test. Trait anxiety predicted biased interpretation of social threat vignettes under high working memory load, but not under low working memory load. In Study 2, 53 undergraduates completed a dot probe task with fear-conditioned Japanese characters serving as threat stimuli. Trait anxiety predicted attentional bias to the threat stimuli but, again, this only occurred under high working memory load. Interestingly however, actual eye movements toward the threat stimuli were only associated with state anxiety, and this was not moderated by working memory load, suggesting that executive control regulates biased threat-processing downstream of initial input processes such as orienting. These results suggest that cognitive loads can exacerbate trait anxiety-related cognitive biases, and therefore represent a useful tool for assessing cognitive biases in future research. More importantly, since biased threat-processing has been implicated in the etiology and maintenance of anxiety, poor executive control may be a risk factor for anxiety disorders. (PsycINFO Database Record (c) 2017 APA, all rights reserved).
ERIC Educational Resources Information Center
Cranford, Kristen N.; Tiettmeyer, Jessica M.; Chuprinko, Bryan C.; Jordan, Sophia; Grove, Nathaniel P.
2014-01-01
Information processing provides a powerful model for understanding how learning occurs and highlights the important role that cognitive load plays in this process. In instances in which the cognitive load of a problem exceeds the available working memory, learning can be seriously hindered. Previously reported methods for measuring cognitive load…
Neural effects of cognitive control load on auditory selective attention
Sabri, Merav; Humphries, Colin; Verber, Matthew; Liebenthal, Einat; Binder, Jeffrey R.; Mangalathu, Jain; Desai, Anjali
2014-01-01
Whether and how working memory disrupts or alters auditory selective attention is unclear. We compared simultaneous event-related potentials (ERP) and functional magnetic resonance imaging (fMRI) responses associated with task-irrelevant sounds across high and low working memory load in a dichotic-listening paradigm. Participants performed n-back tasks (1-back, 2-back) in one ear (Attend ear) while ignoring task-irrelevant speech sounds in the other ear (Ignore ear). The effects of working memory load on selective attention were observed at 130-210 msec, with higher load resulting in greater irrelevant syllable-related activation in localizer-defined regions in auditory cortex. The interaction between memory load and presence of irrelevant information revealed stronger activations primarily in frontal and parietal areas due to presence of irrelevant information in the higher memory load. Joint independent component analysis of ERP and fMRI data revealed that the ERP component in the N1 time-range is associated with activity in superior temporal gyrus and medial prefrontal cortex. These results demonstrate a dynamic relationship between working memory load and auditory selective attention, in agreement with the load model of attention and the idea of common neural resources for memory and attention. PMID:24946314
Relationships between training load, injury, and fitness in sub-elite collision sport athletes.
Gabbett, Tim J; Domrow, Nathan
2007-11-01
The purpose of this study was to develop statistical models that estimate the influence of training load on training injury and physical fitness in collision sport athletes. The incidence of training injuries was studied in 183 rugby league players over two competitive seasons. Participants were assessed for height, body mass, skinfold thickness, vertical jump, 10-m, 20-m and 40-m sprint time, agility, and estimated maximal aerobic power in the off-season, pre-season, mid-season, and end-season. Training load and injury data were summarised into pre-season, early-competition, and late-competition training phases. Individual training load, fitness, and injury data were modelled using a logistic regression model with a binomial distribution and logit link function, while team training load and injury data were modelled using a linear regression model. While physical fitness improved with training, there was no association (P=0.16-0.99) between training load and changes in physical fitness during any of the training phases. However, increases in training load during the early-competition training phase decreased (P= 0.04) agility performance. A relationship (P= 0.01-0.04) was observed between the log of training load and odds of injury during each training phase, resulting in a 1.50 - 2.85 increase in the odds of injury for each arbitrary unit increase in training load. Furthermore, during the pre-season training phase there was a relationship (P= 0.01) between training load and injury incidence within the training load range of 155 and 590 arbitrary units. During the early and late-competition training phases, increases in training load of 175-620 arbitrary units and 145-410 arbitrary units, respectively, resulted in no further increase in injury incidence. These findings demonstrate that increases in training load, particularly during the pre-season training phase, increase the odds of injury in collision sport athletes. However, while increases in training load from 175 to 620 arbitrary units during the early-competition training phase result in no further increase in injury incidence, marked reductions in agility performances can occur. These findings suggest that reductions in training load during the early-competition training phase can reduce the odds of injury without compromising agility performances in collision sport athletes.
Increasing precision of turbidity-based suspended sediment concentration and load estimates.
Jastram, John D; Zipper, Carl E; Zelazny, Lucian W; Hyer, Kenneth E
2010-01-01
Turbidity is an effective tool for estimating and monitoring suspended sediments in aquatic systems. Turbidity can be measured in situ remotely and at fine temporal scales as a surrogate for suspended sediment concentration (SSC), providing opportunity for a more complete record of SSC than is possible with physical sampling approaches. However, there is variability in turbidity-based SSC estimates and in sediment loadings calculated from those estimates. This study investigated the potential to improve turbidity-based SSC, and by extension the resulting sediment loading estimates, by incorporating hydrologic variables that can be monitored remotely and continuously (typically 15-min intervals) into the SSC estimation procedure. On the Roanoke River in southwestern Virginia, hydrologic stage, turbidity, and other water-quality parameters were monitored with in situ instrumentation; suspended sediments were sampled manually during elevated turbidity events; samples were analyzed for SSC and physical properties including particle-size distribution and organic C content; and rainfall was quantified by geologic source area. The study identified physical properties of the suspended-sediment samples that contribute to SSC estimation variance and hydrologic variables that explained variability of those physical properties. Results indicated that the inclusion of any of the measured physical properties in turbidity-based SSC estimation models reduces unexplained variance. Further, the use of hydrologic variables to represent these physical properties, along with turbidity, resulted in a model, relying solely on data collected remotely and continuously, that estimated SSC with less variance than a conventional turbidity-based univariate model, allowing a more precise estimate of sediment loading, Modeling results are consistent with known mechanisms governing sediment transport in hydrologic systems.
Load Variation Influences on Joint Work During Squat Exercise in Reduced Gravity
NASA Technical Reports Server (NTRS)
DeWitt, John K.; Fincke, Renita S.; Logan, Rachel L.; Guilliams, Mark E.; Ploutz-Snyder, Lori L.
2011-01-01
Resistance exercises that load the axial skeleton, such as the parallel squat, are incorporated as a critical component of a space exercise program designed to maximize the stimuli for bone remodeling and muscle loading. Astronauts on the International Space Station perform regular resistance exercise using the Advanced Resistive Exercise Device (ARED). Squat exercises on Earth entail moving a portion of the body weight plus the added bar load, whereas in microgravity the body weight is 0, so all load must be applied via the bar. Crewmembers exercising in microgravity currently add approx.70% of their body weight to the bar load as compensation for the absence of the body weight. This level of body weight replacement (BWR) was determined by crewmember feedback and personal experience without any quantitative data. The purpose of this evaluation was to utilize computational simulation to determine the appropriate level of BWR in microgravity necessary to replicate lower extremity joint work during squat exercise in normal gravity based on joint work. We hypothesized that joint work would be positively related to BWR load.
Wen, Wei; Capolungo, Laurent; Patra, Anirban; ...
2017-02-23
In this work, a physics-based thermal creep model is developed based on the understanding of the microstructure in Fe-Cr alloys. This model is associated with a transition state theory based framework that considers the distribution of internal stresses at sub-material point level. The thermally activated dislocation glide and climb mechanisms are coupled in the obstacle-bypass processes for both dislocation and precipitate-type barriers. A kinetic law is proposed to track the dislocation densities evolution in the subgrain interior and in the cell wall. The predicted results show that this model, embedded in the visco-plastic self-consistent (VPSC) framework, captures well the creepmore » behaviors for primary and steady-state stages under various loading conditions. We also discuss the roles of the mechanisms involved.« less
[The risk of neoplastic processes transformation in cervix uteri].
Kiseleva, V I; Krikunova, L I; Mkrtchian, L S; Liubina, L V; Beziaeva, G P; Panarina, L V; Zamuliaeva, I A
2014-01-01
There was performed a comparative analysis of quantitative load and physical status of human papillomavirus (HPV) type 16 in groups of patients with cervical intraepithelial neoplasia (CIN)--25 people and cervical cancer (CC)--85 people. According to the analysis there were selected criteria appropriate to a combination of adverse factors that characterized HPV- infection and at the same time estimated both quantitative load and physical status of the virus: high viral load (> 6,5 lg copies of HPV DNA per 100000 cells) in episomal form or low load (< 6,5 lg copies of HPV DNA per 100000 cells) in integrated form of the virus. According to calculations a relative chance of appearing of CC in CIN patients with unfavorable combination of factors was 7,5 times higher than in other patients.
Stability of a Cosmetic Multiple Emulsion Loaded with Green Tea Extract
Mahmood, Tariq; Akhtar, Naveed
2013-01-01
Multiple emulsions are excellent and exciting potential systems for the delivery of useful cosmetic agents. The work describes stability of a multiple emulsion for cosmetic purpose, loaded with extract of Camellia sinensis L. (Theaceae) in concentration of 5%. The formulation constitutes of cetyl dimethicone copolyol and polyoxyethylene (20) cetyl ether as emulsifiers and was characterised and monitored for various physicochemical aspects. Centrifugation has no devastating effect on physical destabilization/phase separation observed for 30 days. Mean globule sizes of multiple droplets were found in the range of 10.29 ± 4.4 μm to 12.77 ± 5.1 μm and of inner droplets were in the range of 0.8 ± 0.4 μm to 1.6 ± 0.8 μm. All samples exhibited shear thinning behavior with increase in shear stress. The results of the present study indicate that multiple emulsions can be used as carrier of 5% Camellia sinensis L. extract to enhance desired effects. The developed physically and chemically stable system is an effective system for targeting skin layers; however, long-term stability at elevated temperatures may be needed with suitable modifications, if required. PMID:24058284
NASA Astrophysics Data System (ADS)
Shukla, Mayoorika; Pramila; Dixit, Tejendra; Prakash, Rajiv; Palani, I. A.; Singh, Vipul
2017-11-01
In this work, hydrothermally grown ZnO Nanorods Array (ZNA) has been synthesized over Platinum (Pt) coated glass substrate, for biosensing applications. In-situ addition of strong oxidizing agent viz KMnO4 during hydrothermal growth was found to have profound effect on the physical properties of ZNA. Glucose oxidase (GOx) was later immobilized over ZNA by means of physical adsorption process. Further influence of varying aspect ratio, enzyme loading and surface defects on amperometric glucose biosensor has been analyzed. Significant variation in biosensor performance was observed by varying the amount of KMnO4 addition during the growth. Moreover, investigations revealed that the suppression of surface defects and aspect ratio variation of the ZNA played key role towards the observed improvement in the biosensor performance, thereby significantly affecting the sensitivity and response time of the fabricated biosensor. Among different biosensors fabricated having varied aspect ratio and surface defect density of ZNA, the best electrode resulted into sensitivity and response time to be 18.7 mA cm-2 M-1 and <5 s respectively. The observed results revealed that apart from high aspect ratio nanostructures and the extent of enzyme loading, surface defect density also hold a key towards ZnO nanostructures based bio-sensing applications.
NASA Technical Reports Server (NTRS)
Palosh, L.; Agadzhanyan, N. A.; Davydov, G. A.; Rybakov, B. K.; Sergiyenko, A. S.
1974-01-01
Maximum permissible concentrations of oxygen and carbon dioxide in a controlled atmosphere were determined by evaluating their effects on human gas exchange, blood coagulation, and tolerances to acute hypoxia, acceleration, and physical loads. It was found that functional disturbances depend on the concentration of respiratory gases and the length of stay in an altered atmosphere. By changing the atmospheric composition and by bringing the gaseous environment into accordance with the work and rest regimen and energy expenditures, the general reactivity of the body changes favorably.
2015-12-01
43 1.9 Images of Move Under Direct Fire (Task 10) 44 1.10 Engage Targets with a .50 Caliber M2 Machine Gun (Task 12) 45 1.11 Image of Lay a...Caliber M2 Machine Gun While wearing a fighting load (approximately 83 lb) and working as a member of a two-person team, Soldiers lifted and carried the... M2 HB Machine Gun with tripod (153 lb) a distance of 10 m. Army Standard: Successful completion of the task 13. Emplace Base Plate (11C
2015-12-01
25mm barrel install (Task 5) and engage targets with an M2 machine gun (Task 12). During these tasks, the performance of one individual will affect...TOW Missile Launcher on BFV (Task 8) 43 1.9 Images of Move Under Direct Fire (Task 10) 44 1.10 Engage Targets with a .50 Caliber M2 Machine Gun ...Engage Targets with a .50 Caliber M2 Machine Gun While wearing a fighting load (approximately 83 lb) and working as a member of a two-person team
Zatsiorsky, Vladimir M; Gao, Fan; Latash, Mark L
2005-04-01
According to basic physics, the local effects induced by gravity and acceleration are identical and cannot be separated by any physical experiment. In contrast-as this study shows-people adjust the grip forces associated with gravitational and inertial forces differently. In the experiment, subjects oscillated a vertically-oriented handle loaded with five different weights (from 3.8 N to 13.8 N) at three different frequencies in the vertical plane: 1 Hz, 1.5 Hz and 2.0 Hz. Three contributions to the grip force-static, dynamic, and stato-dynamic fractions-were quantified. The static fraction reflects grip force related to holding a load statically. The stato-dynamic fraction reflects a steady change in the grip force when the same load is moved cyclically. The dynamic fraction is due to acceleration-related adjustments of the grip force during oscillation cycles. The slope of the relation between the grip force and the load force was steeper for the static fraction than for the dynamic fraction. The stato-dynamic fraction increased with the frequency and load. The slope of the dynamic grip force-load force relation decreased with frequency, and as a rule, increased with the load. Hence, when adjusting grip force to task requirements, the central controller takes into account not only the expected magnitude of the load force but also such factors as whether the force is gravitational or inertial and the contributions of the object mass and acceleration to the inertial force. As an auxiliary finding, a complex finger coordination pattern aimed at preserving the rotational equilibrium of the object during shaking movements was reported.
Analysis of load monitoring system in hydraulic mobile cranes
NASA Astrophysics Data System (ADS)
Kalairassan, G.; Boopathi, M.; Mohan, Rijo Mathew
2017-11-01
Load moment limiters or safe load control systems or are very important in crane safety. The system detects the moment of lifting load and compares this actual moment with the rated moment. The system uses multiple sensors such as boom angle sensor, boom length sensor for telescopic booms, pressure transducers for measuring the load, anti-two block switch and roller switches. The system works both on rubber and on outriggers. The sensors measure the boom extension, boom angle and load to give as inputs to the central processing, which calculate the safe working load range for that particular configuration of the crane and compare it with the predetermined safe load. If the load exceeds the safe load, actions will be taken which will reduce the load moment, which is boom telescopic retraction and boom lifting. Anti-two block switch is used to prevent the two blocking condition. The system is calibrated and load tested for at most precision.
A SPECT system simulator built on the SolidWorksTM 3D design package
NASA Astrophysics Data System (ADS)
Li, Xin; Furenlid, Lars R.
2014-09-01
We have developed a GPU-accelerated SPECT system simulator that integrates into instrument-design work flow [1]. This simulator includes a gamma-ray tracing module that can rapidly propagate gamma-ray photons through arbitrary apertures modeled by SolidWorksTM-created stereolithography (.STL) representations with a full com- plement of physics cross sections [2, 3]. This software also contains a scintillation detector simulation module that can model a scintillation detector with arbitrary scintillation crystal shape and light-sensor arrangement. The gamma-ray tracing module enables us to efficiently model aperture and detector crystals in SolidWorksTM and save them as STL file format, then load the STL-format model into this module to generate list-mode results of interacted gamma-ray photon information (interaction positions and energies) inside the detector crystals. The Monte-Carlo scintillation detector simulation module enables us to simulate how scintillation photons get reflected, refracted and absorbed inside a scintillation detector, which contributes to more accurate simulation of a SPECT system.
MacNamara, Annmarie; Ferri, Jamie; Hajcak, Greg
2011-09-01
Emotion regulation decreases the processing of arousing stimuli, as indexed by the late positive potential (LPP), an electrocortical component that varies in amplitude with emotional arousal. Emotion regulation increases activity in the prefrontal areas associated with cognitive control, including the dosolateral prefrontal cortex (DLPFC). The present study manipulated working memory load, known to activate the DLPFC, and recorded the LPP elicited by aversive and neutral IAPS pictures presented during the retention interval. The LPP was larger on low-load compared to high-load trials, and on trials with aversive compared to neutral pictures. These LPP data suggest that emotional content and working memory load have opposing effects on attention to distracting stimuli. State anxiety was associated with reduced modulation of the LPP by working memory load. Results are discussed in terms of competition for attention between emotion and cognition and suggest a relationship between DLPFC activation and the allocation of attentional resources to distracting visual stimuli-a relationship that may be disrupted with increasing anxiety.
Dilly, Marc; Tipold, Andrea; Geuenich, Katja
2016-01-01
Veterinary studies in Germany are regulated by the Veterinary Certification Act (TAppV). The practical part of the education consists of 1,170 hours, whereby up to 850 hours can be spent on the curative work placement. A curative work placement can result in physical and psychological stress in the sense of a professional overload. It is the aim of this study to find out in what areas and to what extent competence is acquired and psychological stress exists in students during their work placement. Veterinary students (n=142) from all German education institutes participated in a voluntary online-study based on Burnout Screening Scales (BOSS) as well as a questionnaire regarding the acquisition of competence and excessive stress during the work placement (FKÜP). The distribution of values for work placement related stress show that such work placement related stress is generally slightly increased (T=60) and lies above that of occupational stresses within the normal population. Work placement related physical complaints also show a significant slight increase (T=61). A value (T=42) within the normal range was determined for the resource values. Few of the students questioned considered themselves to be excessively stressed in favour of a high subjective acquisition of competences. The largest increase regarding the acquisition of competence was noted for the areas of animal handling/restraint and application and injection techniques. In the sense of a perceived excessive demand regarding practical capabilities the areas of emergency management, surgery and medication dispensation were mentioned. With regard to the load structure and the acquisition of competence by veterinary students during their work placement, more support of the individual and a balancing of teaching/learning goals would be desirable and represents a promising approach. PMID:26958657
Bollmann, Steffen; Ghisleni, Carmen; Poil, Simon-Shlomo; Martin, Ernst; Ball, Juliane; Eich-Höchli, Dominique; Klaver, Peter; O'Gorman, Ruth L; Michels, Lars; Brandeis, Daniel
2017-06-01
Attention-deficit/hyperactivity disorder (ADHD) has been associated with spatial working memory as well as frontostriatal core deficits. However, it is still unclear how the link between these frontostriatal deficits and working memory function in ADHD differs in children and adults. This study examined spatial working memory in adults and children with ADHD, focussing on identifying regions demonstrating age-invariant or age-dependent abnormalities. We used functional magnetic resonance imaging to examine a group of 26 children and 35 adults to study load manipulated spatial working memory in patients and controls. In comparison to healthy controls, patients demonstrated reduced positive parietal and frontostriatal load effects, i.e., less increase in brain activity from low to high load, despite similar task performance. In addition, younger patients showed negative load effects, i.e., a decrease in brain activity from low to high load, in medial prefrontal regions. Load effect differences between ADHD and controls that differed between age groups were found predominantly in prefrontal regions. Age-invariant load effect differences occurred predominantly in frontostriatal regions. The age-dependent deviations support the role of prefrontal maturation and compensation in ADHD, while the age-invariant alterations observed in frontostriatal regions provide further evidence that these regions reflect a core pathophysiology in ADHD.
Multi-agent grid system Agent-GRID with dynamic load balancing of cluster nodes
NASA Astrophysics Data System (ADS)
Satymbekov, M. N.; Pak, I. T.; Naizabayeva, L.; Nurzhanov, Ch. A.
2017-12-01
In this study the work presents the system designed for automated load balancing of the contributor by analysing the load of compute nodes and the subsequent migration of virtual machines from loaded nodes to less loaded ones. This system increases the performance of cluster nodes and helps in the timely processing of data. A grid system balances the work of cluster nodes the relevance of the system is the award of multi-agent balancing for the solution of such problems.
Lee, Laura J; Symanski, Elaine; Lupo, Philip J; Tinker, Sarah C; Razzaghi, Hilda; Chan, Wenyaw; Hoyt, Adrienne T; Canfield, Mark A
2017-03-01
We examined the association of an array of estimated maternal occupational physical activities and psychosocial stressors during pregnancy with odds for preterm birth (PTB) and small-for-gestational age (SGA). Data for infants born without major birth defects delivered from 1997 to 2009 whose mothers reported working at least 1 month during pregnancy were obtained from the National Birth Defects Prevention Study. We linked occupational codes to the US Department of Labor's Occupational Information Network, which provides estimates of exposure for multiple domains of physical activity and psychosocial stressors by occupational categories. We conducted factor analysis using principal components extraction with 17 occupational activities and calculated factor scores. ORs for PTB and SGA across quartiles of factor scores in each trimester were computed using logistic regression. Factor analysis grouped occupational domains into 4 groups based on factor loadings. These groups were 'occupational physical activity', 'interpersonal stressor', 'automated work' and 'job responsibility'. High levels of 'occupational physical activity' were significantly associated with SGA (adjusted OR (AOR) for highest quartile compared with lowest quartile of factor score: 1.36; 95% CIs 1.02 to 1.82; p for trend=0.001) and were also positively associated with PTB (AOR: 1.24; 95% CI 0.93 to 1.64; p for trend=0.01). No clear results were observed across domains of psychosocial stressors. Our findings expand understanding of associations between occupational physical activity and psychosocial stressors and PTB and SGA and suggest that additional research is needed to further examine these relationships. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.
Novel percolation phenomena and mechanism of strengthening elastomers by nanofillers.
Wang, Zhenhua; Liu, Jun; Wu, Sizhu; Wang, Wenchuan; Zhang, Liqun
2010-03-28
Nano-strengthening by employing nanoparticles is necessary for high-efficiency strengthening of elastomers, which has already been validated by numerous researches and industrial applications, but the underlying mechanism is still an open challenge. In this work, we mainly focus our attention on studying the variation of the tensile strength of nanofilled elastomers by gradually increasing the filler content, within a low loading range. Interestingly, the percolation phenomenon is observed in the relationship between the tensile strength and the filler loading, which shares some similarities with the percolation phenomenon occurring in rubber toughened plastics. That is, as the loading of nanofillers (carbon black, zinc oxide) increases, the tensile strength of rubber nanocomposites (SBR, EPDM) increases slowly at first, then increases abruptly and finally levels off. Meanwhile, the bigger the particle size, the higher the filler content at the percolation point, and the lower the corresponding tensile strength of rubber nanocomposites. The concept of a critical particle-particle distance (CPD) is proposed to explain the observed percolation phenomenon. It is suggested that rubber strengthening through nanoparticles is attributed to the formation of stretched straight polymer chains between neighbor particles, induced by the slippage of adsorbed polymer chains on the filler surface during tension. Meanwhile, the factors to govern this CPD and the critical minimum particle size (CMPS) figured out in this work are both discussed and analyzed in detail. Within the framework of this percolation phenomenon, this paper also clearly answers two important and intriguing issues: (1) why is it necessary and essential to strengthen elastomers through nanofillers; (2) why does it need enough loading of nanofillers to effectively strengthen elastomers. Moreover, on the basis of the percolation phenomenon, we give out some guidance for reinforcement design of rubbery materials: the interfacial interactions between rubber and fillers cannot be complete chemical bonding, and partial physical absorption of macromolecular chains on the filler surface is necessary, otherwise the formation of stretched straight chains would be seriously hindered. There should exist such an optimum crosslinking density for a certain filler reinforced rubber system, and as well an optimum filler loading for rubber strengthening. Additionally, the different percolation behaviors of Young's modulus, the tensile strength and the electrical conductivity are compared and analyzed in our work. Lastly, molecular simulation indicates that it is not possible to strengthen glassy or hard polymer matrices by incorporating spherical nanoparticles. In general, by providing substantial experimental data and detailed analyses, this work is believed to promote the fundamental understanding of rubber reinforcement, as well provide better guidance for the design of high-performance and multi-functional rubber nanocomposites.
NASA Astrophysics Data System (ADS)
Kinnell, P. I. A.
2015-09-01
Trenouth and Gharabaghi (2015) present two models which replace the EI30 index used as the event erosivity index in the USLE/RUSLE with ones that include runoff and values of EI30 to powers that differ for 1.0 as the event erosivity factor in modelling soil loss for construction sites. Their analysis on the application of these models focused on data from 5 locations as a whole but did not show how the models worked at each location. Practically, the ability to predict sediment yields at a specific location is more relevant than the capacity of a model to predict sediment yields globally. Also, the mathematical structure of their proposed models shows little regard to the physical processes involved in causing erosion and sediment yield. There is still the need to develop event-based empirical models for construction sites that are robust because they give proper consideration to the erosion process involved, and take account of the fact that sediment yield is usually determined from measurements of suspended load whereas soil loss at the scale for which the USLE/RUSLE model was developed includes both suspended load and bed load.
Liu, Shichao; Liu, Xiaoping P; El Saddik, Abdulmotaleb
2014-03-01
In this paper, we investigate the modeling and distributed control problems for the load frequency control (LFC) in a smart grid. In contrast with existing works, we consider more practical and real scenarios, where the communication topology of the smart grid changes because of either link failures or packet losses. These topology changes are modeled as a time-varying communication topology matrix. By using this matrix, a new closed-loop power system model is proposed to integrate the communication topology changes into the dynamics of a physical power system. The globally asymptotical stability of this closed-loop power system is analyzed. A distributed gain scheduling LFC strategy is proposed to compensate for the potential degradation of dynamic performance (mean square errors of state vectors) of the power system under communication topology changes. In comparison to conventional centralized control approaches, the proposed method can improve the robustness of the smart grid to the variation of the communication network as well as to reduce computation load. Simulation results show that the proposed distributed gain scheduling approach is capable to improve the robustness of the smart grid to communication topology changes. © 2013 ISA. Published by ISA. All rights reserved.
The effects of exercise on human articular cartilage
Eckstein, F; Hudelmaier, M; Putz, R
2006-01-01
The effects of exercise on articular hyaline articular cartilage have traditionally been examined in animal models, but until recently little information has been available on human cartilage. Magnetic resonance imaging now permits cartilage morphology and composition to be analysed quantitatively in vivo. This review briefly describes the methodological background of quantitative cartilage imaging and summarizes work on short-term (deformational behaviour) and long-term (functional adaptation) effects of exercise on human articular cartilage. Current findings suggest that human cartilage deforms very little in vivo during physiological activities and recovers from deformation within 90 min after loading. Whereas cartilage deformation appears to become less with increasing age, sex and physical training status do not seem to affect in vivo deformational behaviour. There is now good evidence that cartilage undergoes some type of atrophy (thinning) under reduced loading conditions, such as with postoperative immobilization and paraplegia. However, increased loading (as encountered by elite athletes) does not appear to be associated with increased average cartilage thickness. Findings in twins, however, suggest a strong genetic contribution to cartilage morphology. Potential reasons for the inability of cartilage to adapt to mechanical stimuli include a lack of evolutionary pressure and a decoupling of mechanical competence and tissue mass. PMID:16637874
The effects of exercise on human articular cartilage.
Eckstein, F; Hudelmaier, M; Putz, R
2006-04-01
The effects of exercise on articular hyaline articular cartilage have traditionally been examined in animal models, but until recently little information has been available on human cartilage. Magnetic resonance imaging now permits cartilage morphology and composition to be analysed quantitatively in vivo. This review briefly describes the methodological background of quantitative cartilage imaging and summarizes work on short-term (deformational behaviour) and long-term (functional adaptation) effects of exercise on human articular cartilage. Current findings suggest that human cartilage deforms very little in vivo during physiological activities and recovers from deformation within 90 min after loading. Whereas cartilage deformation appears to become less with increasing age, sex and physical training status do not seem to affect in vivo deformational behaviour. There is now good evidence that cartilage undergoes some type of atrophy (thinning) under reduced loading conditions, such as with postoperative immobilization and paraplegia. However, increased loading (as encountered by elite athletes) does not appear to be associated with increased average cartilage thickness. Findings in twins, however, suggest a strong genetic contribution to cartilage morphology. Potential reasons for the inability of cartilage to adapt to mechanical stimuli include a lack of evolutionary pressure and a decoupling of mechanical competence and tissue mass.
Working memory load modulates microsaccadic rate.
Dalmaso, Mario; Castelli, Luigi; Scatturin, Pietro; Galfano, Giovanni
2017-03-01
Microsaccades are tiny eye movements that individuals perform unconsciously during fixation. Despite that the nature and the functions of microsaccades are still lively debated, recent evidence has shown an association between these micro eye movements and higher order cognitive processes. Here, in two experiments, we specifically focused on working memory and addressed whether differential memory load could be reflected in a modulation of microsaccade dynamics. In Experiment 1, participants memorized a numerical sequence composed of either two (low-load condition) or five digits (high-load condition), appearing at fixation. The results showed a reduction in the microsaccadic rate in the high-load compared to the low-load condition. In Experiment 2, five red or green digits were always presented at fixation. Participants either memorized the color (low-load condition) or the five digits (high-load condition). Hence, visual stimuli were exactly the same in both conditions. Consistent with Experiment 1, microsaccadic rate was lower in the high-load than in the low-load condition. Overall, these findings reveal that an engagement of working memory can have an impact on microsaccadic rate, consistent with the view that microsaccade generation is pervious to top-down processes.
Rolander, Bo; Wåhlin, Charlotte; Johnston, Venerina; Wagman, Petra; Lindmark, Ulrika
2016-08-01
By 2023, fewer dentists are expected in Sweden, at the same time as the demand for dental care is expected to increase. Older people, in particular, are expected to require more dental health than previous generations. To meet this demand, the public sector dentistry in Sweden is moving towards changes in division of labour among dental professionals, including dentists, dental hygienists and dental nurses. However, the impact of this reallocation on the physical and psychosocial wellbeing of employees is unknown. The aim of this study was to compare workplaces with an equal or larger proportion of dental hygienists than dentists (HDH) with workplaces with a larger proportion of dentists than dental hygienists (HD) on the physical and psychosocial work load, musculoskeletal and psychosomatic disorders and sickness presence. A total of 298 persons employed in the Public Dental Service in a Swedish County Council participated in this study. The medium large clinics HDH reported 85% of employee's with considerably more high psychosocial demands compared to employees in medium HD (53%) and large HD (57%). Employees in medium large clinics HDH also reported sleep problems due to work (25%) compared with employees in medium large clinics HD (6%), large clinics HD (11%) and small clinics HDH (3%). Clinic size does not seem to influence the outcome of the HD and HD clinics to any great extent. Of all employees, about 94-100% reported high precision demands and 78-91% poor work postures.
[Influence of sports on development of 10 and 11-year-old boys. II. Spiroergometry].
Popow, C; Haschke, F; Haber, P; Schuster, E; Salzer, H R
1984-01-01
We performed ergometric tests on a bicycle ergometer at the beginning and at the end of a nine month training period of track-and field athletics at school in 21 10 to 11 year old boys (8 hours training per week) and in 12 control subjects (3 1/2 hours training per week). With the exception of total work both groups had similar results at the first test. After nine months most test parameters were significantly improved in both groups. Total working time, total and maximal work, systolic blood pressure at maximal work and relative VO2max. were significantly different in the boys with 8 hours training from values obtained in the control subjects. VO2max. per kg body weight increased from a mean of 48.03 to 57.43 ml x min-1 x kg-2 (19.6%) in the boys with 8 hours training and from 44.70 tp 49.20 ml x min-1 x kg-1 (10.1%) in the control subjects. VO2-max. per kg lean body mass increased only in the boys with 8 hours training. VO2max. related to heart rate increased by 33% in the boys with 8 hours training and by 12% in the controls. The maximal minute ventilation and the minute ventilation at different submaximal working loads decreased in both groups. We conclude that the higher physical activity significantly improved the physical performance and the performance of the cardiovascular and respiratory system in preadolescent boys.
Psychosocial factors and mental work load: a reality perceived by nurses in intensive care units1
Ceballos-Vásquez, Paula; Rolo-González, Gladys; Hérnandez-Fernaud, Estefanía; Díaz-Cabrera, Dolores; Paravic-Klijn, Tatiana; Burgos-Moreno, Mónica
2015-01-01
OBJECTIVE: To analyse the perception of psychosocial factors and mental workload of nurses who work in intensive care units. It is hypothesised that nurses in these units could perceive psychosocial risks, manifesting in a high mental work load. The psychosocial dimension related to the position's cognitive demands is hypothesised to mostly explain mental work load. METHOD: Quantitative study, with a descriptive, cross-sectional, and comparative design. A total of 91% of the intensive care unit populations of three Chilean hospitals was surveyed, corresponding to 111 nurses. The instruments utilised included (A) a biosociodemographic history questionnaire; (b) the SUSESO-ISTAS 21 questionnaire; and (c) the Mental Work Load Subjective Scale (ESCAM, in Spanish). RESULTS: In total, 64% and 57% of participants perceived high levels of exposure to the psychosocial risks Psychosocial demands and Double shift, respectively. In addition, a medium-high level of overall mental load was observed. Positive and significant correlations between some of the SUSESO-ISTAS 21 and ESCAM dimensions were obtained. Using a regression analysis, it was determined that three dimensions of the psychosocial risk questionnaire helped to explain 38% of the overall mental load. CONCLUSION: Intensive care unit nurses felt that inadequate psychosocial factors and mental work overload existed in several of the tested dimensions. PMID:26039303
Psychosocial factors and mental work load: a reality perceived by nurses in intensive care units.
Ceballos-Vásquez, Paula; Rolo-González, Gladys; Hérnandez-Fernaud, Estefanía; Díaz-Cabrera, Dolores; Paravic-Klijn, Tatiana; Burgos-Moreno, Mónica
2015-01-01
To analyse the perception of psychosocial factors and mental workload of nurses who work in intensive care units. It is hypothesised that nurses in these units could perceive psychosocial risks, manifesting in a high mental work load. The psychosocial dimension related to the position's cognitive demands is hypothesised to mostly explain mental work load. Quantitative study, with a descriptive, cross-sectional, and comparative design. A total of 91% of the intensive care unit populations of three Chilean hospitals was surveyed, corresponding to 111 nurses. The instruments utilised included (A) a biosociodemographic history questionnaire; (b) the SUSESO-ISTAS 21 questionnaire; and (c) the Mental Work Load Subjective Scale (ESCAM, in Spanish). In total, 64% and 57% of participants perceived high levels of exposure to the psychosocial risks Psychosocial demands and Double shift, respectively. In addition, a medium-high level of overall mental load was observed. Positive and significant correlations between some of the SUSESO-ISTAS 21 and ESCAM dimensions were obtained. Using a regression analysis, it was determined that three dimensions of the psychosocial risk questionnaire helped to explain 38% of the overall mental load. Intensive care unit nurses felt that inadequate psychosocial factors and mental work overload existed in several of the tested dimensions.
Interaction of threat and verbal working memory in adolescents.
Patel, Nilam; Vytal, Katherine; Pavletic, Nevia; Stoodley, Catherine; Pine, Daniel S; Grillon, Christian; Ernst, Monique
2016-04-01
Threat induces a state of sustained anxiety that can disrupt cognitive processing, and, reciprocally, cognitive processing can modulate an anxiety response to threat. These effects depend on the level of cognitive engagement, which itself varies as a function of task difficulty. In adults, we recently showed that induced anxiety impaired working memory accuracy at low and medium but not high load. Conversely, increasing the task load reduced the physiological correlates of anxiety (anxiety-potentiated startle). The present work examines such threat-cognition interactions as a function of age. We expected threat to more strongly impact working memory in younger individuals by virtue of putatively restricted cognitive resources and weaker emotion regulation. This was tested by examining the influence of age on the interaction of anxiety and working memory in 25 adolescents (10 to 17 years) and 25 adults (22 to 46 years). Working memory load was manipulated using a verbal n-back task. Anxiety was induced using the threat of an aversive loud scream and measured via eyeblink startle. Findings revealed that, in both age groups, accuracy was lower during threat than safe conditions at low and medium but not high load, and reaction times were faster during threat than safe conditions at high load but did not differ at other loads. Additionally, anxiety-potentiated startle was greater during low and medium than high load. Thus, the interactions of anxiety with working memory appear similar in adolescents and adults. Whether these similarities reflect common neural mechanisms would need to be assessed using functional neuroimaging. Published 2015. This article is a U.S. Government work and is in the public domain in the USA.
Vermeij, Anouk; van Beek, Arenda H E A; Reijs, Babette L R; Claassen, Jurgen A H R; Kessels, Roy P C
2014-01-01
Older adults show more bilateral prefrontal activation during cognitive performance than younger adults, who typically show unilateral activation. This over-recruitment has been interpreted as compensation for declining structure and function of the brain. Here we examined how the relationship between behavioral performance and prefrontal activation is modulated by different levels of working-memory load. Eighteen healthy older adults (70.8 ± 5.0 years; MMSE 29.3 ± 0.9) performed a spatial working-memory task (n-back). Oxygenated ([O2Hb]) and deoxygenated ([HHb]) hemoglobin concentration changes were registered by two functional Near-Infrared Spectroscopy (fNIRS) channels located over the left and right prefrontal cortex. Increased working-memory load resulted in worse performance compared to the control condition. [O2Hb] increased with rising working-memory load in both fNIRS channels. Based on the performance in the high working-memory load condition, the group was divided into low and high performers. A significant interaction effect of performance level and hemisphere on [O2Hb] increase was found, indicating that high performers were better able to keep the right prefrontal cortex engaged under high cognitive demand. Furthermore, in the low performers group, individuals with a larger decline in task performance from the control to the high working-memory load condition had a larger bilateral increase of [O2Hb]. The high performers did not show a correlation between performance decline and working-memory load related prefrontal activation changes. Thus, additional bilateral prefrontal activation in low performers did not necessarily result in better cognitive performance. Our study showed that bilateral prefrontal activation may not always be successfully compensatory. Individual behavioral performance should be taken into account to be able to distinguish successful and unsuccessful compensation or declined neural efficiency.
Estryn-Behar, Madeleine; Amar, Emile; Choudat, Dominique
2013-06-01
sick-leave in the course of pregnancy play a role under estimated according to several studies.They bring to light the existence of risk factors concerning the physical load for contractions, sick-leave, hospitalizations and prematurity.The data obtained on the totality of the wage earners of the AP-HP allow to avoid all the possible bias and to determine the potential impact of a policy of reduction of the physical load The data of four years could be analyzed.The used database is PILOT RH, intranet application restoring information extracted from GIPSIE who was until 2008 the institutional software of management of the careers of all the workers of the AP-HP. In 2008,3 937 women having had a maternity leave (ML) accumulated 132 360 days of ordinary sick-leave (OL) (that is 33,6 days on average) without inclusion of the 15 days accepted for "pathological pregnancy" (PP) and "post pregnancy leave". Ordinary sick-leave of all the 53 132 women amounts to 11.5 days by agent. But, the set apart of the women having had a ML reduces the number of days of sick-leave to 9,7 days This difference weighs for 15.6 % of the total of the absenteeism OL. The results are similar on the four years. The analysis by occupational catégory, for 2008, shows that the average number of days of sick-leave, after exclusion of women having had a ML, decreases with the physical load of the posts estimated by the study PRESST-NEXT :ancillary staff 19.9 days, nursing aids 13.7 days, registered nurses 8.2 days, specialized nurses 7.7 days, medico - technical workers 5.7 days and head nurses 5.1 days. For the women having had a ML, the average number of days of ordinary sick-leave, is the most raised for nursing aids (41.9 days) followed by the ancillary staff (36 days) and the registered nurses (36 days) and slightly less for the specialized nurses (28.3 days). On the other hand, in the professions having least physical load the women have less than 25 days of ordinary sick-leave the year of their pregnancy :medico-technical workers 21.3 days, head nurses 23.1 days and administration staff 23.7 days.The results are similar on the four years. For the nurses, it is 25.5% of total ordinary sick-leave that are attributable to the women having had a pregnancy, and 34.4 % if we add OL and 15 days of official "pathological pregnancy". An intervention to reduce the physical load in test hospitals could be led.The reduction of sick-leave in the course of pregnancy can be a fast indicator of evaluation of the efficiency of the investments. The improvements will benefit to all the agents, in the medium term, with a reduction of the risks of musculoskeletal disorders. Such an action also allows to maintain the employability of the older employees and to integrate) persons into situation of handicap in a work which has for them a strong sense and which they do not want to give up.
Wallace, Maeve; Harville, Emily; Theall, Katherine; Webber, Larry; Chen, Wei; Berenson, Gerald
2014-01-01
As a biologically-mediated pathway between adversity and declines in physical health, allostatic load has been frequently hypothesized as a potential contributor to racial disparities in birth outcomes, but empirical evidence is lacking. The purpose of this study was to examine the relationships between maternal preconception allostatic load, race, and adverse birth outcomes within the context of neighborhood-level poverty using data from the Bogalusa Heart Study. Allostatic load was quantified as a count of regulatory biomarkers falling in the highest risk quartile of the sample distribution as measured from a physical examination that took place prior to conception. Consistent with previous findings, African American women resided in more impoverished neighborhoods and had higher allostatic load scores compared to whites; however, allostatic load was not associated with preterm birth or low birthweight in fully adjusted models. These results underscore a need for further refinement of both biologic and contextual measures that capture holistically the way in which stressful conditions and experiences encountered across the life-course influence health potentials and engender inequities in reproductive health outcomes. PMID:24184350
The RFad Method--a new fatigue recovery time assessment for industrial activities.
Silva e Santos, Marcello; Vidal, Mario Cesar Rodriguez; Moreira, Sergio Bastos
2012-01-01
This paper presents a study about fatigue recovery time assessment processes in work activities. It came about due to a demand presented by an automotive industry giant, in need of updating existing cycle time sheets and TAKT time parameters. The company decided to hire an Ergonomics Laboratory with ties to a major Brazilian University in order to evaluate current conditions and establish a new method to either calculate recovery times or validate existing assessment criteria, based in the ergonomics evaluation of the work activities. It is clear that there has been evident evolution in the industrial sector in the past two decades. It brought up fast modernization of industrial processes, not only in production but also in terms of management systems. Due to improved computer and robotics systems, combined with overall operational advancements - like the use of lighter hand tools and more effective hoist systems - most work activities have had its physical effort requirements reduced in the past decades. Thus, compensation factors built into production times need to be reviewed in order to avoid unnecessary costs associated to them. By using ergonomics considerations, we prevent simply removing the physical variables built in rest time calculations without taking on account, for example, additional cognitive load represented by the use of more sophisticated pieces of equipment.
Unni, Anirudh; Ihme, Klas; Jipp, Meike; Rieger, Jochem W.
2017-01-01
Cognitive overload or underload results in a decrease in human performance which may result in fatal incidents while driving. We envision that driver assistive systems which adapt their functionality to the driver’s cognitive state could be a promising approach to reduce road accidents due to human errors. This research attempts to predict variations of cognitive working memory load levels in a natural driving scenario with multiple parallel tasks and to reveal predictive brain areas. We used a modified version of the n-back task to induce five different working memory load levels (from 0-back up to 4-back) forcing the participants to continuously update, memorize, and recall the previous ‘n’ speed sequences and adjust their speed accordingly while they drove for approximately 60 min on a highway with concurrent traffic in a virtual reality driving simulator. We measured brain activation using multichannel whole head, high density functional near-infrared spectroscopy (fNIRS) and predicted working memory load level from the fNIRS data by combining multivariate lasso regression and cross-validation. This allowed us to predict variations in working memory load in a continuous time-resolved manner with mean Pearson correlations between induced and predicted working memory load over 15 participants of 0.61 [standard error (SE) 0.04] and a maximum of 0.8. Restricting the analysis to prefrontal sensors placed over the forehead reduced the mean correlation to 0.38 (SE 0.04), indicating additional information gained through whole head coverage. Moreover, working memory load predictions derived from peripheral heart rate parameters achieved much lower correlations (mean 0.21, SE 0.1). Importantly, whole head fNIRS sampling revealed increasing brain activation in bilateral inferior frontal and bilateral temporo-occipital brain areas with increasing working memory load levels suggesting that these areas are specifically involved in workload-related processing. PMID:28424602
Unni, Anirudh; Ihme, Klas; Jipp, Meike; Rieger, Jochem W
2017-01-01
Cognitive overload or underload results in a decrease in human performance which may result in fatal incidents while driving. We envision that driver assistive systems which adapt their functionality to the driver's cognitive state could be a promising approach to reduce road accidents due to human errors. This research attempts to predict variations of cognitive working memory load levels in a natural driving scenario with multiple parallel tasks and to reveal predictive brain areas. We used a modified version of the n-back task to induce five different working memory load levels (from 0-back up to 4-back) forcing the participants to continuously update, memorize, and recall the previous 'n' speed sequences and adjust their speed accordingly while they drove for approximately 60 min on a highway with concurrent traffic in a virtual reality driving simulator. We measured brain activation using multichannel whole head, high density functional near-infrared spectroscopy (fNIRS) and predicted working memory load level from the fNIRS data by combining multivariate lasso regression and cross-validation. This allowed us to predict variations in working memory load in a continuous time-resolved manner with mean Pearson correlations between induced and predicted working memory load over 15 participants of 0.61 [standard error (SE) 0.04] and a maximum of 0.8. Restricting the analysis to prefrontal sensors placed over the forehead reduced the mean correlation to 0.38 (SE 0.04), indicating additional information gained through whole head coverage. Moreover, working memory load predictions derived from peripheral heart rate parameters achieved much lower correlations (mean 0.21, SE 0.1). Importantly, whole head fNIRS sampling revealed increasing brain activation in bilateral inferior frontal and bilateral temporo-occipital brain areas with increasing working memory load levels suggesting that these areas are specifically involved in workload-related processing.
NASA Technical Reports Server (NTRS)
Fedorov, I. V.; Chernyy, A. V.; Fedorov, A. I.
1978-01-01
During hypokinesia and physical loading (swimming) of rats, the radioactivity of skeletal muscle, liver, kidney, heart, and blood proteins was determined after administration of radioactive amino acids. Tissue protein synthesis decreased during hypokinesia, and decomposition increased. Both synthesis and decomposition increased during physical loading, but anabolic processes predominated in the total tissue balance. The weights of the animals decreased in hypokinesia and increased during increased muscle activity.
[Comparison of the effect of continuous and intermittent physical loading in type I diabetics].
Rusavý, Z; Lacigová, S; Holecek, T; Srámek, V; Novák, I; Tĕsínský, P
1994-07-01
In order to evaluate the optimal mode of physical loads the authors examined 19 diabetics type I without secondary complications. On the second day of an educational-rehabilitation camp the authors subjected the patients to a continuous load-a 40-minute endurance run at a heart rate equal to 60% of the maximal oxygen requirement. On the fifth day an intermittent load with a maximal intensity--training of 4 x 10 minutes with 5-minute intervals was administered. At the onset, during the 20th and 40th minute of the load the titrable acidity, lactate and blood sugar level were assessed. The intermittent load led already after 20 minutes to marked acidosis (titrable acidity = 12) which did not increase after 40 minutes of the load. The authors recorded a statistically significant rise of the lactate level (4.57 mmol/l) which after 40 minutes of the load rose further to 12.3 mmol/l, as compared with values of titrable acidity during the 20th and 40th minute (0.44 and 1.14) and lactate during the 20th and 40th minute (4.57 and 3.86 mmol/l) during a continuous load. After evaluation by the test of linear correlation it appears with regard to the stability of the blood sugar level during a load that an intermittent load is more favourable. The drop of the blood sugar level in time during a continuous load was at the 1 level of significance, in intermittent loads at the 5% of significance. Both types of loads did not lead to hypoglycaemia or other complications and thus both can be used in diabetics type I.
Neural effects of cognitive control load on auditory selective attention.
Sabri, Merav; Humphries, Colin; Verber, Matthew; Liebenthal, Einat; Binder, Jeffrey R; Mangalathu, Jain; Desai, Anjali
2014-08-01
Whether and how working memory disrupts or alters auditory selective attention is unclear. We compared simultaneous event-related potentials (ERP) and functional magnetic resonance imaging (fMRI) responses associated with task-irrelevant sounds across high and low working memory load in a dichotic-listening paradigm. Participants performed n-back tasks (1-back, 2-back) in one ear (Attend ear) while ignoring task-irrelevant speech sounds in the other ear (Ignore ear). The effects of working memory load on selective attention were observed at 130-210ms, with higher load resulting in greater irrelevant syllable-related activation in localizer-defined regions in auditory cortex. The interaction between memory load and presence of irrelevant information revealed stronger activations primarily in frontal and parietal areas due to presence of irrelevant information in the higher memory load. Joint independent component analysis of ERP and fMRI data revealed that the ERP component in the N1 time-range is associated with activity in superior temporal gyrus and medial prefrontal cortex. These results demonstrate a dynamic relationship between working memory load and auditory selective attention, in agreement with the load model of attention and the idea of common neural resources for memory and attention. Copyright © 2014 Elsevier Ltd. All rights reserved.
Ameer, Fatima; Munir, Rimsha; Usman, Hina; Rashid, Rida; Shahjahan, Muhammad; Hasnain, Shahida; Zaidi, Nousheen
2017-04-01
Lipid-load in peripheral blood mononuclear cells (PBMCs) has recently gained attention of the researchers working on nutritional regulation of metabolic health. Previous works have indicated that the metabolic circuitries in the circulating PBMCs are influenced by dietary-intake and macronutrient composition of diet. In the present work, we analyzed the impact of diet and dietary macronutrients on PBMCs' lipid-load. The overall analyses revealed that dietary carbohydrates and fats combinatorially induce triglyceride accumulation in PBMCs. On the other hand, dietary fats were shown to induce significant decrease in PBMCs' cholesterol-load. The effects of various demographic factors -including age, gender and body-weight- on PBMCs' lipid-load were also examined. Body-weight and age were both shown to affect PBMC's lipid-load. Our study fails to provide any direct association between extracellular lipid availability and cholesterol-load in both, freshly isolated and cultured PBMCs. The presented work significantly contributes to the current understanding of the impact of food-consumption, dietary macronutrients, extracellular lipid availability and demographic factors on lipid-load in PBMCs. Copyright © 2017 Elsevier B.V. and Société Française de Biochimie et Biologie Moléculaire (SFBBM). All rights reserved.
NASA Astrophysics Data System (ADS)
Gellerich, Frank N.; Mueller, Tobias; Nioka, Shoko; Hertel, Katrin; Schulte-Mattler, Wilhelm J.; Zierz, Stephan; Chance, Britton
1998-01-01
Noninvasive measurement of changes in oxygenation of human skeletal muscle can be done with a dual-wavelength near infrared (NIR) spectrophotometer. This allows a noninvasive investigation of muscle mitochondria. An exercise protocol was developed to study the load dependent changes in oxygenation of m. vastus lateralis of myopathic patients. On a bicycle ergometer exercise was done periodically. One period consisted of 1.5 min exercise followed by 3 min rest. Work load in the first period was 20 W, and was increased by 10 W for each subsequent period until maximal work load was reached. In 12 healthy volunteers we observed oxygenation of muscle during periods of low work load (warm-up effect). During periods of high work load the muscle deoxygenated. The work load at transition from oxygenation to deoxygenation (deoxygenation threshold) in controls was 75 W. In 3 patients with myopathies, in addition to NIR- spectroscopy, function of mitochondria of specimen of m. vastus lateralis was investigated biochemically. Muscle fibers were skinned with saponin and investigated with high resolution respirometry and multiple substrate-inhibitor- titration. Mitochondrial function was impaired in patients who had abnormal findings in NIR spectroscopy.
NASA Astrophysics Data System (ADS)
Gellerich, Frank N.; Mueller, Tobias; Nioka, Shoko; Hertel, Katrin; Schulte-Mattler, Wilhelm J.; Zierz, Stephan; Chance, Britton
1997-12-01
Noninvasive measurement of changes in oxygenation of human skeletal muscle can be done with a dual-wavelength near infrared (NIR) spectrophotometer. This allows a noninvasive investigation of muscle mitochondria. An exercise protocol was developed to study the load dependent changes in oxygenation of m. vastus lateralis of myopathic patients. On a bicycle ergometer exercise was done periodically. One period consisted of 1.5 min exercise followed by 3 min rest. Work load in the first period was 20 W, and was increased by 10 W for each subsequent period until maximal work load was reached. In 12 healthy volunteers we observed oxygenation of muscle during periods of low work load (warm-up effect). During periods of high work load the muscle deoxygenated. The work load at transition from oxygenation to deoxygenation (deoxygenation threshold) in controls was 75 W. In 3 patients with myopathies, in addition to NIR- spectroscopy, function of mitochondria of specimen of m. vastus lateralis was investigated biochemically. Muscle fibers were skinned with saponin and investigated with high resolution respirometry and multiple substrate-inhibitor- titration. Mitochondrial function was impaired in patients who had abnormal findings in NIR spectroscopy.
Gheldof, Els L M; Vinck, Jan; Vlaeyen, Johan W S; Hidding, Alita; Crombez, Geert
2005-01-01
This cross-sectional questionnaire study investigated the role of pain (pain severity, radiating pain), work characteristics (physical workload, job stressors, job satisfaction), negative affect and pain-related fear in accounting for low back pain (LBP) and sick leave (SL) in 1294 employees from 10 companies in Belgium and the Netherlands. An increased risk for short-term LBP (1-30 days during the last year) was observed for workers reporting high physical workload (OR=2.39), high task exertion (OR=1.63) and high negative affect (OR=1.03). For prolonged LBP (>30 days during the last year) severe pain (OR=13.03), radiating pain (OR=2.37) and fear of work-related activities (OR=3.17) were significant risk factors. A lack of decision latitude decreased the risk of long-term LBP (OR=0.39). Short-term SL (1-30 days during the last year) was associated with severe pain (OR=2.83), high physical workload (OR=2.99) and high fear of movement/(re)injury (OR=1.88). A lack of decision latitude increased the risk of short-term SL (OR=1.92). Long-term SL (>30 days during the last year) was associated with radiating pain (OR=3.80) and high fear of movement/(re)injury (OR=6.35). A lack of co-worker support reduced the risk of long-term SL (OR=0.27). These results suggest that physical load factors are relatively more important in the process leading to short-term LBP and short-term SL, whereas job stressors, severe pain, radiation, and pain-related fear are more important in determining the further course and maintenance of the inability to work. The potential implications of these findings for primary and secondary prevention, and occupational rehabilitation are discussed.
Preparation and application of in-fibre internal standardization solid-phase microextraction.
Zhao, Wennan; Ouyang, Gangfeng; Pawliszyn, Janusz
2007-03-01
The in-fibre standardization method is a novel approach that has been developed for field sampling/sample preparation, in which an internal standard is pre-loaded onto a solid-phase microextraction (SPME) fibre for calibration of the extraction of target analytes in field samples. The same method can also be used for in-vial sample analysis. In this study, different techniques to load the standard to a non-porous SPME fibre were investigated. It was found that the appropriateness of the technique depends on the physical properties of the standards that are used for the analysis. Headspace extraction of the standard dissolved in pumping oil works well for volatile compounds. Conversely, headspace extraction of the pure standard is an effective approach for semi-volatile compounds. For compounds with low volatility, a syringe-fibre transfer method and direct extraction of the standard dissolved in a solvent exhibited a good reproducibility (<5% RSD). The main advantage of the approaches investigated in this study is that the standard generation vials can be reused for hundreds of analyses without exhibiting significant loss. Moreover, most of the standard loading processes studied can be performed automatically, which is efficient and precise. Finally, the standard loading technique and in-fibre standardization method were applied to a complex matrix (milk) and the results illustrated that the matrix effect can be effectively compensated for with this approach.
Daylighting performance and thermal implications of skylights vs. south-facing roof monitors
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rosenbaum, M.; Coldham, B.
1997-12-31
This paper reports the results of a comparison of skylights vs. south-facing roof monitors for daylighting the north wall zone of a 10,000 ft{sup 2} office building near Manchester, NH. A physical model was constructed and tested. Simultaneously, the building`s annual thermal performance was modeled with Energy-10 hourly simulation software, and its peak heating and cooling load performance was modeled with the Carrier Corp. Hourly Analysis Program (HAP). Apertures were built into the roof of the model, and several skylight and south-facing roof monitor configurations were tested in both clear and overcast conditions. A design goal was to have themore » building be daylit on overcast as well as clear days. This goal was based more on enhancement of the working environment than it was on electrical energy savings. Monitors with overhangs performed poorly in the overcast conditions--it was determined that 2.4 times as much monitor aperture was needed to yield equivalent light levels in overcast conditions. The thermal models showed that the annual heating and cooling energy cost for the building was the same for either strategy, but that peak cooling loads and peak heating loads were lower with the skylit version. The authors concluded that skylights were preferred over monitors in this application, due to similar annual energy costs, lower peak loads, and lower construction cost.« less
Occupational Physical Loading Tasks and Knee Osteoarthritis: A Review of the Evidence
Ezzat, Allison M.
2014-01-01
ABSTRACT Purpose: To perform a systematic review with best evidence synthesis examining the literature on the relationship between occupational loading tasks and knee osteoarthritis (OA). Methods: Two databases were searched to identify articles published between 1946 and April, 2011. Eligible studies were those that (1) included adults reporting on their employment history; (2) measured individuals' exposure to work-related activities with heavy loading in the knee joint; and (3) identified presence of knee OA (determined by X-ray), cartilage defects associated with knee OA (identified by magnetic resonance imaging), or joint replacement surgery. Results: A total of 32 articles from 31 studies met the inclusion criteria. We found moderate evidence that combined heavy lifting and kneeling is a risk factor for knee OA, with odds ratios (OR) varying from 1.8 to 7.9, and limited evidence for heavy lifting (OR=1.4–7.3), kneeling (OR=1.5–6.9), stair climbing (OR=1.6–5.1), and occupational groups (OR=1.4–4.7) as risk factors. When examined by sex, moderate level evidence of knee OA was found in men; however, the evidence in women was limited. Conclusions: Further high-quality prospective studies are warranted to provide further evidence on the role of occupational loading tasks in knee OA, particularly in women. PMID:24719516
Neuromuscular control of lumbar instability following static work of various loads.
Le, Brook; Davidson, Bradley; Solomonow, Deborah; Zhou, Bing He; Lu, Yun; Patel, Vikas; Solomonow, Moshe
2009-01-01
Neuromuscular control of lumbar stability following exposure to prolonged static work, under low and high loads, was assessed in the in vivo feline model. Six sessions of 10 min work at 20N with 10 min between rest was compared to a group subjected to the same protocol but carrying high loads of 60N. Displacement and tension developed in the spine at the instant the multifidus muscles applied stabilizing contractions, and their amplitudes were obtained from their electromyogram (EMG). Significant (P < 0.001) laxity developed in the various viscoelastic tissues of the lumbar spine that did not recover during and up to 7 h of rest postwork. Simultaneously, there was a significant (P < 0.001) decrease in muscular activity in the 3-4 h immediately postwork under low load but only during the first hour in the high load group. After that period the musculature compensated for the laxity of the viscoelastic tissues by a significant (P < 0.001) increase in activity in the high-load group and a nonsignificant increase in the low group. It was concluded that during 1-3 h immediately poststatic work a significant decrease in the stabilizing function of viscoelastic tissues together with a significant decrease in muscular activity is present, and they render the spine unstable and exposed to high risk of injury. Performance of prolonged static work under low loads, while not harmful during the work, cannot be designated as a "no-risk" condition, as it may result in injury postwork.
McKendrick, Ryan; Shaw, Tyler; de Visser, Ewart; Saqer, Haneen; Kidwell, Brian; Parasuraman, Raja
2014-05-01
Assess team performance within a net-worked supervisory control setting while manipulating automated decision aids and monitoring team communication and working memory ability. Networked systems such as multi-unmanned air vehicle (UAV) supervision have complex properties that make prediction of human-system performance difficult. Automated decision aid can provide valuable information to operators, individual abilities can limit or facilitate team performance, and team communication patterns can alter how effectively individuals work together. We hypothesized that reliable automation, higher working memory capacity, and increased communication rates of task-relevant information would offset performance decrements attributed to high task load. Two-person teams performed a simulated air defense task with two levels of task load and three levels of automated aid reliability. Teams communicated and received decision aid messages via chat window text messages. Task Load x Automation effects were significant across all performance measures. Reliable automation limited the decline in team performance with increasing task load. Average team spatial working memory was a stronger predictor than other measures of team working memory. Frequency of team rapport and enemy location communications positively related to team performance, and word count was negatively related to team performance. Reliable decision aiding mitigated team performance decline during increased task load during multi-UAV supervisory control. Team spatial working memory, communication of spatial information, and team rapport predicted team success. An automated decision aid can improve team performance under high task load. Assessment of spatial working memory and the communication of task-relevant information can help in operator and team selection in supervisory control systems.
Radiopure Metal-Loaded Liquid Scintillator
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rosero, Richard; Yeh, Minfang
2015-03-18
Metal-loaded liquid scintillator plays a key role in particle and nuclear physics experiments. The applications of metal ions in various neutrino experiments and the purification methods for different scintillator components are discussed in this paper.
Radiopure metal-loaded liquid scintillator
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rosero, Richard; Yeh, Minfang, E-mail: yeh@bnl.gov
2015-08-17
Metal-loaded liquid scintillator plays a key role in particle and nuclear physics experiments. The applications of metal ions in various neutrino experiments and the purification methods for different scintillator components are discussed in this paper.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tomar, Vikas; Haque, Aman; Hattar, Khalid
In-core nuclear materials including fuel pins and cladding materials fail due to issues including corrosion, mechanical wear, and pellet cladding interaction. In most such scenario microstructure dependent and corrosioninduced chemistry dependent property changes significantly affect performance of cladding, pellet, and housing. Emphasis of this work was on replace conventional pellet-cladding material models with a new straingradient viscoplasticity model that is informed by transmission electron microscopy (TEM) based measurements and by nanomechanical Raman spectroscopy (NMRS) based measurements. The TEM measurements are quantitative in nature and therefore reveal stress-strain relations with simultaneous insights into mechanisms of deformation at nanoscale. The NMRS measurementsmore » reveal the similar information at mesoscale along with additional information on relating local microstructural stresses with applied stresses. The resulting information is used to fit constants in the strain gradient viscoplasticity model as well as to validate one. During TEM measurements, a micro-electro-mechanical system based setup was developed with mechanical actuation, sensing, heating, and electrical loading. Contrary to post-mortem analysis or qualitative visualization, this setup combines direct visualization of the mechanisms behind deformation with measurement of stress, strain, thermal and electrical properties. The unique research philosophy of visualizing the microstructure at high resolution while measuring the properties led to fundamental understanding in grain size and temperature effects on measured mechanical properties such as fracture toughness. A key contribution is the role of mechanical loading boundary conditions to deconvolute the insitu TEM based nanoscale and NMRS based mesoscale data to bulk behavior. First the literature based pellet cladding mechanical interaction model based on the work of Retel’s and Williamson’s in literature work to predict tempurature and stress distribution in cladding and pellet at normal operating condition was analyzed. Later the data was fitted to find constants for a viscoplastic strain gradient model. The developed model still needs to be refined and calibrated using various experimental results. That remains the focus of future work. Overall, a major thrust of the work was therefore on active control of the microstructure (grain size, defect density and types) exploiting the multi-physics coupling in materials. In particular, using experiments the synergy of current density, mechanical stress and temperature were studied to annihilate defects and recrystallize grains. The developed model is being examined for implementation in BISON. Multiple invited talks, international journal publications, and conference publications were performed by students supported on this work. Another output is support multiple PhD and masters thesis students who will be an important asset for future basic nuclear research. Future Work Recommendations: A nuclear reactor operates under significant variations of thermal loads due to energy cycling and mechanical loads due to constraint effects. Significant thermal and chemical diffusion takes place at the pallet-cladding level. While the proposed work established new experimental approach and new dataset for Zircaloy-4, the irradiation level was in the range of 1-2 dpa. Samples with higher dpa need to be examined. Therefore, a continual of support of the performed work is essential. Currently, these are the only experiments that can measure the produced data. The work also needs to be extended to different fuel types and cladding types such as SiC and FeCrAl based claddings. A combination of datasets for these materials can then be used to analyze accurately predict behavior of critical pellet cladding systems in accident scenario with high heat flux and high thermal loads. This is a BIG unknown as if now.« less
Allostatic Load and Health in the Older Population of England: A Crossed-Lagged Analysis
Read, Sanna; Grundy, Emily
2014-01-01
Objective Allostatic load, a composite measure of accumulated physical wear and tear, has been proposed as an early sign of physiological dysregulation predictive of health problems, functional limitation, and disability. However, much previous research has been cross sectional and few studies consider repeated measures. We investigate the directionality of associations between allostatic load, self-rated health, and a measure of physical function (walking speed). Methods The sample included men and women 60 and older who participated in Wave 2 (2004) and Wave 4 (2008) of the English Longitudinal Study of Ageing (n = 6132 in Wave 2). Allostatic load was measured with nine biomarkers using a multisystem summary approach. Self-rated health was measured using a global 5 point summary indicator. Time to walk 8 ft was used as a measure of function. We fitted and tested autoregressive cross-lagged models between the allostatic load measure, self-rated health, and walking speed in Waves 2 and 4. Models were adjusted for age, sex, educational level, and smoking status at Wave 2 and for time-varying indicators of marital status, wealth, physical activity, and social support. Results Allostatic load predicted slower walking speed (standardized estimate = −0.08, 95% confidence interval [CI] = −0.10 to −0.05). Better self-rated health predicted faster walking speed (standardized estimate = 0.11, 95% CI = 0.08-0.13) as well as lower allostatic load (standardized estimate = −0.15, 95% CI = −0.22 to −0.09), whereas paths from allostatic load and walking speed to self-rated health were weaker (standardized estimates = −0.05 [95% CI = −0.07 to −0.02] and 0.06 [95% CI = 0.04–0.08]). Conclusions Allostatic load can be a useful risk indicator of subsequent poor health or function. PMID:25153937
Transient Three-Dimensional Side Load Analysis of a Film Cooled Nozzle
NASA Technical Reports Server (NTRS)
Wang, Ten-See; Guidos, Mike
2008-01-01
Transient three-dimensional numerical investigations on the side load physics for an engine encompassing a film cooled nozzle extension and a regeneratively cooled thrust chamber, were performed. The objectives of this study are to identify the three-dimensional side load physics and to compute the associated aerodynamic side load using an anchored computational methodology. The computational methodology is based on an unstructured-grid, pressure-based computational fluid dynamics formulation, and a transient inlet history based on an engine system simulation. Ultimately, the computational results will be provided to the nozzle designers for estimating of effect of the peak side load on the nozzle structure. Computations simulating engine startup at ambient pressures corresponding to sea level and three high altitudes were performed. In addition, computations for both engine startup and shutdown transients were also performed for a stub nozzle, operating at sea level. For engine with the full nozzle extension, computational result shows starting up at sea level, the peak side load occurs when the lambda shock steps into the turbine exhaust flow, while the side load caused by the transition from free-shock separation to restricted-shock separation comes at second; and the side loads decreasing rapidly and progressively as the ambient pressure decreases. For the stub nozzle operating at sea level, the computed side loads during both startup and shutdown becomes very small due to the much reduced flow area.
Dynamic Multiple Work Stealing Strategy for Flexible Load Balancing
NASA Astrophysics Data System (ADS)
Adnan; Sato, Mitsuhisa
Lazy-task creation is an efficient method of overcoming the overhead of the grain-size problem in parallel computing. Work stealing is an effective load balancing strategy for parallel computing. In this paper, we present dynamic work stealing strategies in a lazy-task creation technique for efficient fine-grain task scheduling. The basic idea is to control load balancing granularity depending on the number of task parents in a stack. The dynamic-length strategy of work stealing uses run-time information, which is information on the load of the victim, to determine the number of tasks that a thief is allowed to steal. We compare it with the bottommost first work stealing strategy used in StackThread/MP, and the fixed-length strategy of work stealing, where a thief requests to steal a fixed number of tasks, as well as other multithreaded frameworks such as Cilk and OpenMP task implementations. The experiments show that the dynamic-length strategy of work stealing performs well in irregular workloads such as in UTS benchmarks, as well as in regular workloads such as Fibonacci, Strassen's matrix multiplication, FFT, and Sparse-LU factorization. The dynamic-length strategy works better than the fixed-length strategy because it is more flexible than the latter; this strategy can avoid load imbalance due to overstealing.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Renlund, Anita Mariana; Tappan, Alexander Smith; Miller, Jill C.
The HMX {beta}-{delta} solid-solid phase transition, which occurs as HMX is heated near 170 C, is linked to increased reactivity and sensitivity to initiation. Thermally damaged energetic materials (EMs) containing HMX therefore may present a safety concern. Information about the phase transition is vital to predictive safety models for HMX and HMX-containing EMs. We report work on monitoring the phase transition with real-time Raman spectroscopy aimed towards obtaining a better understanding of physical properties of HMX through the phase transition. HMX samples were confined in a cell of minimal free volume in a displacement-controlled or load-controlled arrangement. The cell wasmore » heated and then cooled at controlled rates while real-time Raman spectroscopic measurements were performed. Raman spectroscopy provides a clear distinction between the phases of HMX because the vibrational transitions of the molecule change with conformational changes associated with the phase transition. Temperature of phase transition versus load data are presented for both the heating and cooling cycles in the load-controlled apparatus, and general trends are discussed. A weak dependence of the temperature of phase transition on load was discovered during the heating cycle, with higher loads causing the phase transition to occur at a higher temperature. This was especially true in the temperature of completion of phase transition data as opposed to the temperature of onset of phase transition data. A stronger dependence on load was observed in the cooling cycle, with higher loads causing the reverse phase transitions to occur at a higher cooling temperature. Also, higher loads tended to cause the phase transition to occur over a longer period of time in the heating cycle and over a shorter period of time in the cooling cycle. All three of the pure HMX phases ({alpha}, {beta} and {delta}) were detected on cooling of the heated samples, either in pure form or as a mixture.« less
Work and health, a blind spot in curative healthcare? A pilot study.
Lötters, Freek J B; Foets, Marleen; Burdorf, Alex
2011-09-01
Most workers with musculoskeletal disorders on sick leave often consult with regular health care before entering a specific work rehabilitation program. However, it remains unclear to what extent regular healthcare contributes to the timely return to work (RTW). Moreover, several studies have indicated that it might postpone RTW. There is a need to establish the influence of regular healthcare on RTW as outcome; "Does visiting a regular healthcare provider influence the duration of sickness absence and recurrent sick leave due to musculoskeletal disorders?". A cohort of workers on sick leave for 2-6 weeks due to a-specific musculoskeletal disorders was followed for 12 months. The main outcomes for the present analysis were: duration of sickness absence till 100% return to work and recurrent sick leave after initial RTW. Cox regression analyses were conducted with visiting a general health practitioner, physical therapist, or medical specialist during the sick leave period as independent variables. Each regression model was adjusted for variables known to influence health care utilization like age, sex, diagnostic group, pain intensity, functional disability, general health perception, severity of complaints, job control, and physical load at work. Patients visiting a medical specialist reported higher pain intensity and more functional limitations and also had a worse health perception at start of the sick leave period compared with those not visiting a specialist. Visiting a medical specialist delayed return to work significantly (HR = 2.10; 95%CI 1.43-3.07). After approximately 8 weeks on sick leave workers visiting a physical therapist returned to work faster than other workers. A recurrent episode of sick leave during the follow up quick was initiated by higher pain intensity and more functional limitations at the moment of fully return to work. Visiting a primary healthcare provider during the sickness absence period did not influence the occurrence of a new sick leave period. Despite the adjustment for severity of the musculoskeletal disorder, visiting a medical specialist was associated with a delayed full return to work. More attention to the factor 'labor' in the regular healthcare is warranted, especially for those patients experiencing substantial functional limitations due to musculoskeletal disorders.
NASA Technical Reports Server (NTRS)
Mulhall, B. D. L.
1980-01-01
The results of the analysis of the external environment of the FBI Fingerprint Identification Division are presented. Possible trends in the future environment of the Division that may have an effect on the work load were projected to determine if future work load will lie within the capability range of the proposed new system, AIDS 3. Two working models of the environment were developed, the internal and external model, and from these scenarios the projection of possible future work load volume and mixture was developed. Possible drivers of work load change were identified and assessed for upper and lower bounds of effects. Data used for the study were derived from historical information, analysis of the current situation and from interviews with various agencies who are users of or stakeholders in the present system.
Design of a decision tool for hydromorphological restoration of water bodies in Walloon Region
NASA Astrophysics Data System (ADS)
Lambot, Francis; de Le Court, Bernard; Petit, François; Hallot, Eric; Peeters, Alexandre; Descy, Jean-Pierre; Verniers, Gisèle; Latli, Adrien
2010-05-01
The pilot project WALPHY (LIFE + Environment LIFE07 ENV/B/000038, UE-funded) develops a structured approach aiming at improving hydromorphological quality of the upstream Meuse basin in order to achieve the "good ecological status" required by the Water Framework Directive (WFD 2000/60). It began in January 2009 for a period of 5 years. River's biological recovery needs the recovery of river's structure and physical dynamics. Returning to "good ecological status" inevitably involves physical restoration of affected rivers. Physical component of aquatic environment acts as a limiting factor for their functioning. Three types of modification are key obstacles for river good ecological status: (i) fluxes alteration (discharge, sedimentation…), (ii) forms alteration (uniform facies…) and (iii) biotopes access alteration (lateral connections breaks, modification of the continuity upstream/downstream…). Therefore hydromorphology is needed to implement the WFD. To respond to this legal necessity, we develop a unique, useful and suitable methodology in Walloon Region to determine and schedule river physical quality restoration works. This methodology has been applied on 3 "risk water bodies". The works are based on two axes : longitudinal continuity and transversal continuity. The two first selected water bodies (Bocq river, eastern tributary of the Meuse) seem to be convenient for the restoration works which concern the longitudinal continuity due to the presence of dams and other obstacles usually between 1 and 3 m high. These works consist in dam management (weir removal or fish passage) taking into account hydromorphological (bedload transport) and biological (invertebrate or fish species free movement) impacts. The third water bodies (Eau Blanche river, western tributary of the Meuse) presents straightened rivers with artificial banks, witch consequently own bad connections between the stream and its floodplain. This water bodies should therefore be appropriated for the works based on the transversal continuity recovery. They consist in enhancing straightened river channels, restoring meanders or bank restoration. The first river restoration works will take place from summer 2010. A monitoring has already been undertaken to draw up the situation before the restoration works, witch will be able to compare to the situations during and after works. In addition, a natural site has been chosen to enable any comparison with the intervention sites. The geomorphological monitoring is based on physical and sedimentological parameters (substrate cartography, velocity measures, stream channel DEM, topography and sedimentological index). The ecological monitoring consists in analysing the physical and chemical parameters (turbidity, suspended sediment load). It also analyses the biological quality through 3 indicators: macrophytes, macroinvertebrates and fishes. Among other, a microhabitats method has been improved and applied on 3 intervention sites and 1 natural site. The microhabitats cartography results from both the flow velocity cartography and the substrate cartography. With this method, the physical quality of each intervention site could be compared with the natural site and above all with the future situation. Our method is also useful to inventory precisely invertebrates and to characterise fish habitats.
Development of an aeroelastic methodology for surface morphing rotors
NASA Astrophysics Data System (ADS)
Cook, James R.
Helicopter performance capabilities are limited by maximum lift characteristics and vibratory loading. In high speed forward flight, dynamic stall and transonic flow greatly increase the amplitude of vibratory loads. Experiments and computational simulations alike have indicated that a variety of active rotor control devices are capable of reducing vibratory loads. For example, periodic blade twist and flap excitation have been optimized to reduce vibratory loads in various rotors. Airfoil geometry can also be modified in order to increase lift coefficient, delay stall, or weaken transonic effects. To explore the potential benefits of active controls, computational methods are being developed for aeroelastic rotor evaluation, including coupling between computational fluid dynamics (CFD) and computational structural dynamics (CSD) solvers. In many contemporary CFD/CSD coupling methods it is assumed that the airfoil is rigid to reduce the interface by single dimension. Some methods retain the conventional one-dimensional beam model while prescribing an airfoil shape to simulate active chord deformation. However, to simulate the actual response of a compliant airfoil it is necessary to include deformations that originate not only from control devices (such as piezoelectric actuators), but also inertial forces, elastic stresses, and aerodynamic pressures. An accurate representation of the physics requires an interaction with a more complete representation of loads and geometry. A CFD/CSD coupling methodology capable of communicating three-dimensional structural deformations and a distribution of aerodynamic forces over the wetted blade surface has not yet been developed. In this research an interface is created within the Fully Unstructured Navier-Stokes (FUN3D) solver that communicates aerodynamic forces on the blade surface to University of Michigan's Nonlinear Active Beam Solver (UM/NLABS -- referred to as NLABS in this thesis). Interface routines are developed for transmission of force and deflection information to achieve an aeroelastic coupling updated at each time step. The method is validated first by comparing the integrated aerodynamic work at CFD and CSD nodes to verify work conservation across the interface. Second, the method is verified by comparing the sectional blade loads and deflections of a rotor in hover and in forward flight with experimental data. Finally, stability analyses for pitch/plunge flutter and camber flutter are performed with comprehensive CSD/low-order-aerodynamics and tightly coupled CFD/CSD simulations and compared to analytical solutions of Peters' thin airfoil theory to verify proper aeroelastic behavior. The effects of simple harmonic camber actuation are examined and compared to the response predicted by Peters' finite-state (F-S) theory. In anticipation of active rotor experiments inside enclosed facilities, computational simulations are performed to evaluate the capability of CFD for accurately simulating flow inside enclosed volumes. A computational methodology for accurately simulating a rotor inside a test chamber is developed to determine the influence of test facility components and turbulence modeling and performance predictions. A number of factors that influence the physical accuracy of the simulation, such as temporal resolution, grid resolution, and aeroelasticity are also evaluated.
Kamalinia, Mojtaba; Nasl Saraji, Gebreal; Kee, Dohyung; Hosseini, Mostafa; Choobineh, Alireza
2013-01-01
Changes in industries and work practices have coincided with work-related musculoskeletal disorders (MSDs). This study was conducted to determine the prevalence of MSDs and to assess postural loading in assembly workers of an Iranian telecommunication manufacturing company. Data were collected from 193 randomly selected workers in 4 units of the company. The Nordic musculoskeletal disorders questionnaire and the UBC ergonomic checklist were used as data collection tools. Loading on the upper body assessment (LUBA) was used to assess postural loading. Lower back symptoms were the most prevalent problems among the workers (67.9%). LUBA showed that most assembly workers (94.3%) had experienced considerable and high postural loading (postural load index, PLI > 5). Regression analyses revealed that lighting, rotation, contact stress, repetition, gender and age were factors associated with symptoms. Work-related MSDs occurred at a high rate among workers. Postural loading requires consideration. Any ergonomic intervention should focus on eliminating ergonomic factors associated with symptoms.
Coughlan, Garrett F; Green, Brian S; Pook, Paul T; Toolan, Eoin; O'Connor, Sean P
2011-08-01
Descriptive. To evaluate the physical demands of an international Rugby Union-level game using a global positioning system (GPS). Elite Rugby Union teams currently employ the latest technology to monitor and evaluate physical demands of training and games on their players. GPS data from 2 players, a back and a forward, were collected during an international Rugby Union game. Locomotion speed, total body load, and body load sustained in tackles and scrums were analyzed. Players completed an average distance of 6715 m and spent the major portion of the game standing or walking, interspersed with medium- and high-intensity running activities. The back performed a higher number of high-intensity sprints and reached a greater maximal speed. Body load data revealed that high levels of gravitational force are sustained in tackling and scrum tasks. The current study provides a detailed GPS analysis of the physical demands of international Rugby Union players. These data, when combined with game video footage, may assist sports medicine professionals in understanding the demands of the game and mechanism of injury, as well as improving injury rehabilitation.
Using bench press load to predict upper body exercise loads in physically active individuals.
Wong, Del P; Ngo, Kwan-Lung; Tse, Michael A; Smith, Andrew W
2013-01-01
This study investigated whether loads for assistance exercises of the upper body can be predicted from the loads of the bench press exercise. Twenty-nine physically active collegiate students (age: 22.6 ± 2.5; weight training experience: 2.9 ± 2.1 years; estimated 1RM bench press: 54.31 ± 14.60 kg; 1RM: body weight ratio: 0.80 ± 0.22; BMI: 22.7 ± 2.1 kg·m(-2)) were recruited. The 6RM loads for bench press, barbell bicep curl, overhead dumbbell triceps extension, hammer curl and dumbbell shoulder press were measured. Test-retest reliability for the 5 exercises as determined by Pearson product moment correlation coefficient was very high to nearly perfect (0.82-0.98, p < 0.01). The bench press load was significantly correlated with the loads of the 4 assistance exercises (r ranged from 0.80 to 0.93, p < 0.01). Linear regression revealed that the bench press load was a significant (R(2) range from 0.64 to 0.86, p < 0.01) predictor for the loads of the 4 assistance exercises. The following 6RM prediction equations were determined: (a) Hammer curl = Bench press load (0.28) + 6.30 kg, (b) Barbell biceps curl = Bench press load (0.33) + 6.20 kg, (c) Overhead triceps extension = Bench press load (0.33) - 0.60 kg, and (d) Dumbbell shoulder press = Bench press load (0.42) + 5.84 kg. The difference between the actual load and the predicted load using the four equations ranged between 6.52% and 8.54%, such difference was not significant. Fitness professionals can use the 6RM bench press load as a time effective and accurate method to predict training loads for upper body assistance exercises. Key pointsThe bench press load was significantly correlated with the loads of the 4 assistance exercises.No significant differences were found between the actual load and the predicted load in the four equations.6RM bench press load can be a time effective and accurate method to predict training loads for upper body assistance exercises.
Using Bench Press Load to Predict Upper Body Exercise Loads in Physically Active Individuals
Wong, Del P.; Ngo, Kwan-Lung; Tse, Michael A.; Smith, Andrew W.
2013-01-01
This study investigated whether loads for assistance exercises of the upper body can be predicted from the loads of the bench press exercise. Twenty-nine physically active collegiate students (age: 22.6 ± 2.5; weight training experience: 2.9 ± 2.1 years; estimated 1RM bench press: 54.31 ± 14.60 kg; 1RM: body weight ratio: 0.80 ± 0.22; BMI: 22.7 ± 2.1 kg·m-2) were recruited. The 6RM loads for bench press, barbell bicep curl, overhead dumbbell triceps extension, hammer curl and dumbbell shoulder press were measured. Test-retest reliability for the 5 exercises as determined by Pearson product moment correlation coefficient was very high to nearly perfect (0.82-0.98, p < 0.01). The bench press load was significantly correlated with the loads of the 4 assistance exercises (r ranged from 0.80 to 0.93, p < 0.01). Linear regression revealed that the bench press load was a significant (R2 range from 0.64 to 0.86, p < 0.01) predictor for the loads of the 4 assistance exercises. The following 6RM prediction equations were determined: (a) Hammer curl = Bench press load (0.28) + 6.30 kg, (b) Barbell biceps curl = Bench press load (0.33) + 6.20 kg, (c) Overhead triceps extension = Bench press load (0.33) - 0.60 kg, and (d) Dumbbell shoulder press = Bench press load (0.42) + 5.84 kg. The difference between the actual load and the predicted load using the four equations ranged between 6.52% and 8.54%, such difference was not significant. Fitness professionals can use the 6RM bench press load as a time effective and accurate method to predict training loads for upper body assistance exercises. Key points The bench press load was significantly correlated with the loads of the 4 assistance exercises. No significant differences were found between the actual load and the predicted load in the four equations. 6RM bench press load can be a time effective and accurate method to predict training loads for upper body assistance exercises. PMID:24149723
To hear or not to hear: Voice processing under visual load.
Zäske, Romi; Perlich, Marie-Christin; Schweinberger, Stefan R
2016-07-01
Adaptation to female voices causes subsequent voices to be perceived as more male, and vice versa. This contrastive aftereffect disappears under spatial inattention to adaptors, suggesting that voices are not encoded automatically. According to Lavie, Hirst, de Fockert, and Viding (2004), the processing of task-irrelevant stimuli during selective attention depends on perceptual resources and working memory. Possibly due to their social significance, faces may be an exceptional domain: That is, task-irrelevant faces can escape perceptual load effects. Here we tested voice processing, to study whether voice gender aftereffects (VGAEs) depend on low or high perceptual (Exp. 1) or working memory (Exp. 2) load in a relevant visual task. Participants adapted to irrelevant voices while either searching digit displays for a target (Exp. 1) or recognizing studied digits (Exp. 2). We found that the VGAE was unaffected by perceptual load, indicating that task-irrelevant voices, like faces, can also escape perceptual-load effects. Intriguingly, the VGAE was increased under high memory load. Therefore, visual working memory load, but not general perceptual load, determines the processing of task-irrelevant voices.
Biomechanical evaluation of an innovative spring-loaded axillary crutch design.
Zhang, Yanxin; Liu, Guangyu; Xie, Shengquan; Liger, Aurélien
2011-01-01
We evaluated an innovative spring-loaded crutch design by comparing its performance with standard crutches through a biomechanical approach. Gait analysis was conducted for 7 male subjects under two conditions: walking with standard crutches and with spring-loaded crutches. Three-dimensional kinematic data and ground reaction force were recorded. Spatiotemporal variables, external mechanical work, and elastic energy (for spring crutches) were calculated based on recorded data. The trajectories of vertical ground reaction forces with standard crutches had two main peaks before and after mid-stance, and those with optimized spring-loaded crutches had only one main peak. The magnitude of external mechanical work was significantly higher with spring-loaded crutches than with standard crutches for all subjects, and the transferred elastic energy made an important contribution to the total external work for spring-loaded crutches. No significant differences in the spatiotemporal parameters were observed. Optimized spring-loaded crutches can efficiently propel crutch walkers and could reduce the total energy expenditure in crutch walking. Further research using optimized spring-loaded crutches with respect to energy efficiency is recommended.
Code of Federal Regulations, 2013 CFR
2013-10-01
... that for polypropylene fiber rope. (d) Welded steel chain which is not marked or labeled to enable... load limit shall be considered to have a working load limit equal to one-fourth of the nominal strength... Grade 43 high test Grade 70 transport Grade 80 alloy Grade 100 alloy 1. 7 (1/4) 580 (1,300) 1,180 (2,600...
Code of Federal Regulations, 2014 CFR
2014-10-01
... that for polypropylene fiber rope. (d) Welded steel chain which is not marked or labeled to enable... load limit shall be considered to have a working load limit equal to one-fourth of the nominal strength... Grade 43 high test Grade 70 transport Grade 80 alloy Grade 100 alloy 1. 7 (1/4) 580 (1,300) 1,180 (2,600...
Code of Federal Regulations, 2012 CFR
2012-10-01
... that for polypropylene fiber rope. (d) Welded steel chain which is not marked or labeled to enable... load limit shall be considered to have a working load limit equal to one-fourth of the nominal strength... Grade 43 high test Grade 70 transport Grade 80 alloy Grade 100 alloy 1. 7 (1/4) 580 (1,300) 1,180 (2,600...
Jiang, Tongying; Wu, Chao; Gao, Yikun; Zhu, Wenquan; Wan, Long; Wang, Zhanyou; Wang, Siling
2014-02-01
Organic porous material is a promising carrier for enhancing the dissolution of poorly water soluble drug. The aim of the present study was to enhance dissolution and oral bioavailability of lovastatin (LV) by preparing a porous starch microsphere foam (PSM) using a novel method, meanwhile, looking into the mechanism of improving dissolution of LV. PSM was prepared by the W/O emulsion-freeze thawing method. The porous structure of PSM was characterized by scanning electron microscopy (SEM) and nitrogen adsorption/desorption analysis. The adsorption role of nanopores on the drug dissolution and physical state of LV was systematically studied by instrumental analysis, and in vitro and in vivo drug dissolution studies. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was used to evaluate carrier cytotoxicity. The SEM images of PSM showed nanometer-sized pores. Physical state characterization indicated that porous structure effectively limited the degree of crystallinity of LV. The results of in vitro and in vivo tests testified that PSM accelerated the release of LV and enhanced its oral bioavailability in comparison with crude LV and commercial capsules. The loaded PSM powder indicated a good physical stability under storage for 12 months. MTT assay shows PSM has no toxicity for Caco-2 cell. The preparation was a promising method to produce small and uniform PSM with markedly enhanced dissolution rate and oral bioavailability due to the spatial confinement effect of porous structure. The present work demonstrates the significant potential for the use of PSM as a novel delivery system for poorly water soluble drugs.
Asymmetric Spatial Processing Under Cognitive Load.
Naert, Lien; Bonato, Mario; Fias, Wim
2018-01-01
Spatial attention allows us to selectively process information within a certain location in space. Despite the vast literature on spatial attention, the effect of cognitive load on spatial processing is still not fully understood. In this study we added cognitive load to a spatial processing task, so as to see whether it would differentially impact upon the processing of visual information in the left versus the right hemispace. The main paradigm consisted of a detection task that was performed during the maintenance interval of a verbal working memory task. We found that increasing cognitive working memory load had a more negative impact on detecting targets presented on the left side compared to those on the right side. The strength of the load effect correlated with the strength of the interaction on an individual level. The implications of an asymmetric attentional bias with a relative disadvantage for the left (vs the right) hemispace under high verbal working memory (WM) load are discussed.
ERIC Educational Resources Information Center
Bevilacqua, Andy
2017-01-01
Recent upgrades to cognitive load theory suggest that evolutionary processes have shaped the way that working memory processes cultural and social information. According to evolutionarily educational psychologists, some forms of information are processed with lower working memory loads than other forms. The former are evolutionarily salient and…
Bed load transport in gravel-bed rivers
Jeffrey J. Barry
2007-01-01
Bed load transport is a fundamental physical process in alluvial rivers, building and maintaining a channel geometry that reflects both the quantity and timing of water and the volume and caliber of sediment delivered from the watershed. A variety of formulae have been developed to predict bed load transport in gravel-bed rivers, but testing of the equations in natural...
Fridberg, Daniel J; Gerst, Kyle R; Finn, Peter R
2013-12-01
Substance dependence and antisocial psychopathology, such as a history of childhood conduct disorder (HCCD), are associated with impulsive or disadvantageous decision making and reduced working memory capacity (WMC). Reducing WMC via a working memory load increases disadvantageous decision making in healthy adults, but no previous studies have examined this effect in young adults with substance dependence and HCCD. Young adults with substance dependence (SubDep; n=158, 71 female), substance dependence and HCCD (SubDep+HCCD; n=72, 24 female), and control participants (n=152, 84 female) completed a test of decision making (the Iowa Gambling Task; IGT) with or without a concurrent working memory load intended to tax WMC. Outcomes were (i) net advantageous decisions on the IGT, and (ii) preferences for infrequent- versus frequent-punishment decks. SubDep+HCCD men made fewer advantageous decisions on the IGT than control men without a load, but there were no group differences among women in that condition. Load was associated with fewer advantageous decisions for SubDep+HCCD women and control men, but not for men or women in the other groups. Participants showed greater preference for infrequent-punishment, advantageous decks under load as well. There are gender differences in the effects of substance dependence, HCCD, and working memory load on decision making on the IGT. Decision making by control men and SubDep+HCCD women suffered the most under load. Load increases preferences for less-frequent punishments, similar to a delay discounting effect. Future research should clarify the cognitive and neural mechanisms underlying these effects. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.
Reducing physical size limits for low-frequency horn loudspeaker systems
NASA Astrophysics Data System (ADS)
Honeycutt, Richard Allison
From 1881 until the present day, many excellent scholars have studied acoustic horns. This dissertation begins by discussing over eighty results of such study. Next, the methods of modeling horn behavior are examined with an emphasis on the prediction of throat impedance. Because of the time constraints in a product-design environment, in which the results of this study may be used, boundary-element and cascaded-section types of analysis were not considered due to their time intensiveness. Of the methods studied, an analytical process based upon Olson's adaptation of Webster's analysis is selected as the most accurate of the rapid methods, although other good methods exist. Reasons and extent of inaccuracy are discussed. The concept of interleaved horn loading is introduced: it involves using two horns of different parameters, fed by a single driver, with a view toward interleaving and thus smoothing the impedance peaks of the separate horns to produce a smoother response. The validity of the technique is demonstrated both theoretically and practically. Then the reactance annulling technique is explained and tested experimentally. It is found to work well, but the exact parameter values involved are not found to be critical. Finally, the considerations involved in building a practical working system are discussed, and a preliminary working model reviewed. Future work could be directed toward finding the optimum parameter values for the two "parallel horns" whose impedances are to be interleaved, as well as the system parameters that determine these optimum values. Also, further experimental investigation or ported loading of the back air chamber would be useful.
40 CFR 1065.110 - Work inputs and outputs, accessory work, and operator demand.
Code of Federal Regulations, 2013 CFR
2013-07-01
...-current and water-brake dynamometers for any testing that does not involve engine motoring, which is... resistor load bank to simulate electrical loads. (3) Pump, compressor, and turbine work. Use pumps, compressors, and turbines that are of the type and capacity installed in use. Use working fluids that are of...
40 CFR 1065.110 - Work inputs and outputs, accessory work, and operator demand.
Code of Federal Regulations, 2014 CFR
2014-07-01
...-current and water-brake dynamometers for any testing that does not involve engine motoring, which is... resistor load bank to simulate electrical loads. (3) Pump, compressor, and turbine work. Use pumps, compressors, and turbines that are of the type and capacity installed in use. Use working fluids that are of...
40 CFR 1065.110 - Work inputs and outputs, accessory work, and operator demand.
Code of Federal Regulations, 2012 CFR
2012-07-01
...-current and water-brake dynamometers for any testing that does not involve engine motoring, which is... resistor load bank to simulate electrical loads. (3) Pump, compressor, and turbine work. Use pumps, compressors, and turbines that are of the type and capacity installed in use. Use working fluids that are of...