TWANG-PIC, a novel gyro-averaged one-dimensional particle-in-cell code for interpretation of gyrotron experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Braunmueller, F., E-mail: falk.braunmueller@epfl.ch; Tran, T. M.; Alberti, S.

A new gyrotron simulation code for simulating the beam-wave interaction using a monomode time-dependent self-consistent model is presented. The new code TWANG-PIC is derived from the trajectory-based code TWANG by describing the electron motion in a gyro-averaged one-dimensional Particle-In-Cell (PIC) approach. In comparison to common PIC-codes, it is distinguished by its computation speed, which makes its use in parameter scans and in experiment interpretation possible. A benchmark of the new code is presented as well as a comparative study between the two codes. This study shows that the inclusion of a time-dependence in the electron equations, as it is themore » case in the PIC-approach, is mandatory for simulating any kind of non-stationary oscillations in gyrotrons. Finally, the new code is compared with experimental results and some implications of the violated model assumptions in the TWANG code are disclosed for a gyrotron experiment in which non-stationary regimes have been observed and for a critical case that is of interest in high power gyrotron development.« less

Coupling MHD and PIC models in 2 dimensions

NASA Astrophysics Data System (ADS)

Daldorff, L.; Toth, G.; Sokolov, I.; Gombosi, T. I.; Lapenta, G.; Brackbill, J. U.; Markidis, S.; Amaya, J.

2013-12-01

Even for extended fluid plasma models, like Hall, anisotropic ion pressure and multi fluid MHD, there are still many plasma phenomena that are not well captured. For this reason, we have coupled the Implicit Particle-In-Cell (iPIC3D) code with the BATSRUS global MHD code. The PIC solver is applied in a part of the computational domain, for example, in the vicinity of reconnection sites, and overwrites the MHD solution. On the other hand, the fluid solver provides the boundary conditions for the PIC code. To demonstrate the use of the coupled codes for magnetospheric applications, we perform a 2D magnetosphere simulation, where BATSRUS solves for Hall MHD in the whole domain except for the tail reconnection region, which is handled by iPIC3D.

Proceedings of the 14th International Conference on the Numerical Simulation of Plasmas

NASA Astrophysics Data System (ADS)

Partial Contents are as follows: Numerical Simulations of the Vlasov-Maxwell Equations by Coupled Particle-Finite Element Methods on Unstructured Meshes; Electromagnetic PIC Simulations Using Finite Elements on Unstructured Grids; Modelling Travelling Wave Output Structures with the Particle-in-Cell Code CONDOR; SST--A Single-Slice Particle Simulation Code; Graphical Display and Animation of Data Produced by Electromagnetic, Particle-in-Cell Codes; A Post-Processor for the PEST Code; Gray Scale Rendering of Beam Profile Data; A 2D Electromagnetic PIC Code for Distributed Memory Parallel Computers; 3-D Electromagnetic PIC Simulation on the NRL Connection Machine; Plasma PIC Simulations on MIMD Computers; Vlasov-Maxwell Algorithm for Electromagnetic Plasma Simulation on Distributed Architectures; MHD Boundary Layer Calculation Using the Vortex Method; and Eulerian Codes for Plasma Simulations.

Testing COBOL Programs by Mutation. Volume I. Introduction to the CMS.1 System.

DTIC Science & Technology

1980-02-01

ALTER-OCCURS><SYMBOL TABLE location><code><x> where code = 0 means "add 1 to occurs", = 1 means "subtract 1 from occurs". 4 Insert a filler ( PIC X) in...REC. 31 01 OLD-REC. 32 03 FILLER PIC X. 33 03 OLD-KEY PIC X(12). 34 03 FILLER PIC X(67). 35S to NEdETF 36 RECORD CONTATS 90 CHARACTERS 37 LABEL RECORDS...ARE STANDARD 3S DATA RECORD IS NEd-REC. 39 01 NEd-REC. AO 03 FILLER PIC 1. Al 03 NEW-(FY PIC X(12). A2 03 FILLER PIC 1(6?). 43 ED PMTHR 44 RECORD

Parallel Higher-order Finite Element Method for Accurate Field Computations in Wakefield and PIC Simulations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Candel, A.; Kabel, A.; Lee, L.

Over the past years, SLAC's Advanced Computations Department (ACD), under SciDAC sponsorship, has developed a suite of 3D (2D) parallel higher-order finite element (FE) codes, T3P (T2P) and Pic3P (Pic2P), aimed at accurate, large-scale simulation of wakefields and particle-field interactions in radio-frequency (RF) cavities of complex shape. The codes are built on the FE infrastructure that supports SLAC's frequency domain codes, Omega3P and S3P, to utilize conformal tetrahedral (triangular)meshes, higher-order basis functions and quadratic geometry approximation. For time integration, they adopt an unconditionally stable implicit scheme. Pic3P (Pic2P) extends T3P (T2P) to treat charged-particle dynamics self-consistently using the PIC (particle-in-cell)more » approach, the first such implementation on a conformal, unstructured grid using Whitney basis functions. Examples from applications to the International Linear Collider (ILC), Positron Electron Project-II (PEP-II), Linac Coherent Light Source (LCLS) and other accelerators will be presented to compare the accuracy and computational efficiency of these codes versus their counterparts using structured grids.« less

Hand washing compliance among retail food establishment workers in Minnesota.

PubMed

Allwood, Paul B; Jenkins, Timothy; Paulus, Colleen; Johnson, Lars; Hedberg, Craig W

2004-12-01

Inadequate hand washing by food workers is an important contributing factor to foodborne disease outbreaks in retail food establishments (RFEs). We conducted a survey of RFEs to investigate the effect of hand washing training, availability of hand washing facilities, and the ability of the person in charge (PIC) to describe hand washing according to the Minnesota Food Code (food code) on workers' ability to demonstrate food code-compliant hand washing. Only 52% of the PICs could describe the hand washing procedure outlined in the food code, and only 48% of workers could demonstrate code-compliant hand washing. The most common problems observed were failure to wash for 20 s and failure to use a fingernail brush. There was a strong positive association between the PIC being a certified food manager and being able to describe the food code hand washing procedure (odds ratio [OR], 5.5; 95% confidence interval [CI], 2.2 to 13.7), and there was an even stronger association between the PIC being able to describe hand washing and workers being able to demonstrate code-compliant hand washing (OR, 15; 95% CI, 6 to 37). Significant associations were detected among correct hand washing demonstration, physical infrastructure for hand washing, and the hand washing training methods used by the establishment. However, the principal determinant of successful hand washing demonstration was the PIC's ability to describe proper hand washing procedure. These results suggest that improving hand washing practices among food workers will require interventions that address PIC knowledge of hand washing requirement and procedure and the development and implementation of effective hand washing training methods.

Lorentz boosted frame simulation technique in Particle-in-cell methods

NASA Astrophysics Data System (ADS)

Yu, Peicheng

In this dissertation, we systematically explore the use of a simulation method for modeling laser wakefield acceleration (LWFA) using the particle-in-cell (PIC) method, called the Lorentz boosted frame technique. In the lab frame the plasma length is typically four orders of magnitude larger than the laser pulse length. Using this technique, simulations are performed in a Lorentz boosted frame in which the plasma length, which is Lorentz contracted, and the laser length, which is Lorentz expanded, are now comparable. This technique has the potential to reduce the computational needs of a LWFA simulation by more than four orders of magnitude, and is useful if there is no or negligible reflection of the laser in the lab frame. To realize the potential of Lorentz boosted frame simulations for LWFA, the first obstacle to overcome is a robust and violent numerical instability, called the Numerical Cerenkov Instability (NCI), that leads to unphysical energy exchange between relativistically drifting particles and their radiation. This leads to unphysical noise that dwarfs the real physical processes. In this dissertation, we first present a theoretical analysis of this instability, and show that the NCI comes from the unphysical coupling of the electromagnetic (EM) modes and Langmuir modes (both main and aliasing) of the relativistically drifting plasma. We then discuss the methods to eliminate them. However, the use of FFTs can lead to parallel scalability issues when there are many more cells along the drifting direction than in the transverse direction(s). We then describe an algorithm that has the potential to address this issue by using a higher order finite difference operator for the derivative in the plasma drifting direction, while using the standard second order operators in the transverse direction(s). The NCI for this algorithm is analyzed, and it is shown that the NCI can be eliminated using the same strategies that were used for the hybrid FFT/Finite Difference solver. This scheme also requires a current correction and filtering which require FFTs. However, we show that in this case the FFTs can be done locally on each parallel partition. We also describe how the use of the hybrid FFT/Finite Difference or the hybrid higher order finite difference/second order finite difference methods permit combining the Lorentz boosted frame simulation technique with another "speed up" technique, called the quasi-3D algorithm, to gain unprecedented speed up for the LWFA simulations. In the quasi-3D algorithm the fields and currents are defined on an r--z PIC grid and expanded in azimuthal harmonics. The expansion is truncated with only a few modes so it has similar computational needs of a 2D r--z PIC code. We show that NCI has similar properties in r--z as in z-x slab geometry and show that the same strategies for eliminating the NCI in Cartesian geometry can be effective for the quasi-3D algorithm leading to the possibility of unprecedented speed up. We also describe a new code called UPIC-EMMA that is based on fully spectral (FFT) solver. The new code includes implementation of a moving antenna that can launch lasers in the boosted frame. We also describe how the new hybrid algorithms were implemented into OSIRIS. Examples of LWFA using the boosted frame using both UPIC-EMMA and OSIRIS are given, including the comparisons against the lab frame results. We also describe how to efficiently obtain the boosted frame simulations data that are needed to generate the transformed lab frame data, as well as how to use a moving window in the boosted frame. The NCI is also a major issue for modeling relativistic shocks with PIC algorithm. In relativistic shock simulations two counter-propagating plasmas drifting at relativistic speeds are colliding against each other. We show that the strategies for eliminating the NCI developed in this dissertation are enabling such simulations being run for much longer simulation times, which should open a path for major advances in relativistic shock research. (Abstract shortened by ProQuest.).

Comparisons of time explicit hybrid kinetic-fluid code Architect for Plasma Wakefield Acceleration with a full PIC code

DOE Office of Scientific and Technical Information (OSTI.GOV)

Massimo, F., E-mail: francesco.massimo@ensta-paristech.fr; Dipartimento SBAI, Università di Roma “La Sapienza“, Via A. Scarpa 14, 00161 Roma; Atzeni, S.

Architect, a time explicit hybrid code designed to perform quick simulations for electron driven plasma wakefield acceleration, is described. In order to obtain beam quality acceptable for applications, control of the beam-plasma-dynamics is necessary. Particle in Cell (PIC) codes represent the state-of-the-art technique to investigate the underlying physics and possible experimental scenarios; however PIC codes demand the necessity of heavy computational resources. Architect code substantially reduces the need for computational resources by using a hybrid approach: relativistic electron bunches are treated kinetically as in a PIC code and the background plasma as a fluid. Cylindrical symmetry is assumed for themore » solution of the electromagnetic fields and fluid equations. In this paper both the underlying algorithms as well as a comparison with a fully three dimensional particle in cell code are reported. The comparison highlights the good agreement between the two models up to the weakly non-linear regimes. In highly non-linear regimes the two models only disagree in a localized region, where the plasma electrons expelled by the bunch close up at the end of the first plasma oscillation.« less

A 2D electrostatic PIC code for the Mark III Hypercube

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ferraro, R.D.; Liewer, P.C.; Decyk, V.K.

We have implemented a 2D electrostastic plasma particle in cell (PIC) simulation code on the Caltech/JPL Mark IIIfp Hypercube. The code simulates plasma effects by evolving in time the trajectories of thousands to millions of charged particles subject to their self-consistent fields. Each particle`s position and velocity is advanced in time using a leap frog method for integrating Newton`s equations of motion in electric and magnetic fields. The electric field due to these moving charged particles is calculated on a spatial grid at each time by solving Poisson`s equation in Fourier space. These two tasks represent the largest part ofmore » the computation. To obtain efficient operation on a distributed memory parallel computer, we are using the General Concurrent PIC (GCPIC) algorithm previously developed for a 1D parallel PIC code.« less

The Utility of the WHO ICD-10-AM Pastoral Intervention Codings Within Religious, Pastoral and Spiritual Care Research.

PubMed

Carey, Lindsay B; Cohen, Jeffrey

2015-10-01

The World Health Organization (WHO) 'Pastoral Intervention Codings' were first released in 2002 as part of the 'International Statistical Classification of Diseases and Related Health Problems' (WHO 2002). The purpose of the WHO pastoral intervention codings (colloquially abbreviated as 'WHO-PICs') was to record and account for the religious, pastoral and/or spiritual interventions of chaplains and volunteers providing care to patients and other clients experiencing religious and/or spiritual health and well-being issues. The intent of such WHO codings was to provide information in five areas: statistical, research, clinical, education and policy. The purpose of this paper predominantly accounts for research although it does intersect and relate to other WHO priorities. Over the past 10 years, research by the current and associated authors to test the efficacy of the WHO-PICs has been implemented in a number of different health and welfare contexts that have engaged chaplaincy personnel. In summary, while the WHO-PICs are yet to be more widely utilized internationally, the codings have largely proven to be valuable indices appropriate to a variety of contexts. Research utilizing the WHO-PICs, however, has also revealed the necessity for a number of changes and inclusions to be implemented. Recommendations concerning the future utilisation of the WHO-PICs are made, as are recommendations for these codings to be further developed and promoted by the WHO, so as to more accurately record religious, pastoral and spiritual interventions.

Electron-beam-ion-source (EBIS) modeling progress at FAR-TECH, Inc

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, J. S., E-mail: kim@far-tech.com; Zhao, L., E-mail: kim@far-tech.com; Spencer, J. A., E-mail: kim@far-tech.com

FAR-TECH, Inc. has been developing a numerical modeling tool for Electron-Beam-Ion-Sources (EBISs). The tool consists of two codes. One is the Particle-Beam-Gun-Simulation (PBGUNS) code to simulate a steady state electron beam and the other is the EBIS-Particle-In-Cell (EBIS-PIC) code to simulate ion charge breeding with the electron beam. PBGUNS, a 2D (r,z) electron gun and ion source simulation code, has been extended for efficient modeling of EBISs and the work was presented previously. EBIS-PIC is a space charge self-consistent PIC code and is written to simulate charge breeding in an axisymmetric 2D (r,z) device allowing for full three-dimensional ion dynamics.more » This 2D code has been successfully benchmarked with Test-EBIS measurements at Brookhaven National Laboratory. For long timescale (< tens of ms) ion charge breeding, the 2D EBIS-PIC simulations take a long computational time making the simulation less practical. Most of the EBIS charge breeding, however, may be modeled in 1D (r) as the axial dependence of the ion dynamics may be ignored in the trap. Where 1D approximations are valid, simulations of charge breeding in an EBIS over long time scales become possible, using EBIS-PIC together with PBGUNS. Initial 1D results are presented. The significance of the magnetic field to ion dynamics, ion cooling effects due to collisions with neutral gas, and the role of Coulomb collisions are presented.« less

Efficient Modeling of Laser-Plasma Accelerators with INF&RNO

NASA Astrophysics Data System (ADS)

Benedetti, C.; Schroeder, C. B.; Esarey, E.; Geddes, C. G. R.; Leemans, W. P.

2010-11-01

The numerical modeling code INF&RNO (INtegrated Fluid & paRticle simulatioN cOde, pronounced "inferno") is presented. INF&RNO is an efficient 2D cylindrical code to model the interaction of a short laser pulse with an underdense plasma. The code is based on an envelope model for the laser while either a PIC or a fluid description can be used for the plasma. The effect of the laser pulse on the plasma is modeled with the time-averaged poderomotive force. These and other features allow for a speedup of 2-4 orders of magnitude compared to standard full PIC simulations while still retaining physical fidelity. The code has been benchmarked against analytical solutions and 3D PIC simulations and here a set of validation tests together with a discussion of the performances are presented.

A portable platform for accelerated PIC codes and its application to GPUs using OpenACC

NASA Astrophysics Data System (ADS)

Hariri, F.; Tran, T. M.; Jocksch, A.; Lanti, E.; Progsch, J.; Messmer, P.; Brunner, S.; Gheller, C.; Villard, L.

2016-10-01

We present a portable platform, called PIC_ENGINE, for accelerating Particle-In-Cell (PIC) codes on heterogeneous many-core architectures such as Graphic Processing Units (GPUs). The aim of this development is efficient simulations on future exascale systems by allowing different parallelization strategies depending on the application problem and the specific architecture. To this end, this platform contains the basic steps of the PIC algorithm and has been designed as a test bed for different algorithmic options and data structures. Among the architectures that this engine can explore, particular attention is given here to systems equipped with GPUs. The study demonstrates that our portable PIC implementation based on the OpenACC programming model can achieve performance closely matching theoretical predictions. Using the Cray XC30 system, Piz Daint, at the Swiss National Supercomputing Centre (CSCS), we show that PIC_ENGINE running on an NVIDIA Kepler K20X GPU can outperform the one on an Intel Sandy bridge 8-core CPU by a factor of 3.4.

Fourier-Bessel Particle-In-Cell (FBPIC) v0.1.0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lehe, Remi; Kirchen, Manuel; Jalas, Soeren

The Fourier-Bessel Particle-In-Cell code is a scientific simulation software for relativistic plasma physics. It is a Particle-In-Cell code whose distinctive feature is to use a spectral decomposition in cylindrical geometry. This decomposition allows to combine the advantages of spectral 3D Cartesian PIC codes (high accuracy and stability) and those of finite-difference cylindrical PIC codes with azimuthal decomposition (orders-of-magnitude speedup when compared to 3D simulations). The code is built on Python and can run both on CPU and GPU (the GPU runs being typically 1 or 2 orders of magnitude faster than the corresponding CPU runs.) The code has the exactmore » same output format as the open-source PIC codes Warp and PIConGPU (openPMD format: openpmd.org) and has a very similar input format as Warp (Python script with many similarities). There is therefore tight interoperability between Warp and FBPIC, and this interoperability will increase even more in the future.« less

Efficient Modeling of Laser-Plasma Accelerators with INF and RNO

DOE Office of Scientific and Technical Information (OSTI.GOV)

Benedetti, C.; Schroeder, C. B.; Esarey, E.

2010-11-04

The numerical modeling code INF and RNO (INtegrated Fluid and paRticle simulatioN cOde, pronounced 'inferno') is presented. INF and RNO is an efficient 2D cylindrical code to model the interaction of a short laser pulse with an underdense plasma. The code is based on an envelope model for the laser while either a PIC or a fluid description can be used for the plasma. The effect of the laser pulse on the plasma is modeled with the time-averaged poderomotive force. These and other features allow for a speedup of 2-4 orders of magnitude compared to standard full PIC simulations whilemore » still retaining physical fidelity. The code has been benchmarked against analytical solutions and 3D PIC simulations and here a set of validation tests together with a discussion of the performances are presented.« less

Review of particle-in-cell modeling for the extraction region of large negative hydrogen ion sources for fusion

NASA Astrophysics Data System (ADS)

Wünderlich, D.; Mochalskyy, S.; Montellano, I. M.; Revel, A.

2018-05-01

Particle-in-cell (PIC) codes are used since the early 1960s for calculating self-consistently the motion of charged particles in plasmas, taking into account external electric and magnetic fields as well as the fields created by the particles itself. Due to the used very small time steps (in the order of the inverse plasma frequency) and mesh size, the computational requirements can be very high and they drastically increase with increasing plasma density and size of the calculation domain. Thus, usually small computational domains and/or reduced dimensionality are used. In the last years, the available central processing unit (CPU) power strongly increased. Together with a massive parallelization of the codes, it is now possible to describe in 3D the extraction of charged particles from a plasma, using calculation domains with an edge length of several centimeters, consisting of one extraction aperture, the plasma in direct vicinity of the aperture, and a part of the extraction system. Large negative hydrogen or deuterium ion sources are essential parts of the neutral beam injection (NBI) system in future fusion devices like the international fusion experiment ITER and the demonstration reactor (DEMO). For ITER NBI RF driven sources with a source area of 0.9 × 1.9 m2 and 1280 extraction apertures will be used. The extraction of negative ions is accompanied by the co-extraction of electrons which are deflected onto an electron dump. Typically, the maximum negative extracted ion current is limited by the amount and the temporal instability of the co-extracted electrons, especially for operation in deuterium. Different PIC codes are available for the extraction region of large driven negative ion sources for fusion. Additionally, some effort is ongoing in developing codes that describe in a simplified manner (coarser mesh or reduced dimensionality) the plasma of the whole ion source. The presentation first gives a brief overview of the current status of the ion source development for ITER NBI and of the PIC method. Different PIC codes for the extraction region are introduced as well as the coupling to codes describing the whole source (PIC codes or fluid codes). Presented and discussed are different physical and numerical aspects of applying PIC codes to negative hydrogen ion sources for fusion as well as selected code results. The main focus of future calculations will be the meniscus formation and identifying measures for reducing the co-extracted electrons, in particular for deuterium operation. The recent results of the 3D PIC code ONIX (calculation domain: one extraction aperture and its vicinity) for the ITER prototype source (1/8 size of the ITER NBI source) are presented.

Pseudospectral Model for Hybrid PIC Hall-effect Thruster Simulation

DTIC Science & Technology

2015-07-01

and Fernandez6 (hybrid- PIC ). This work follows the example of Lam and Fernandez but substitutes a spectral description in the azimuthal direction to...Paper 3. DATES COVERED (From - To) July 2015-July 2015 4. TITLE AND SUBTITLE Pseudospectral model for hybrid PIC Hall-effect thruster simulationect...of a pseudospectral azimuthal-axial hybrid- PIC HET code which is designed to explicitly resolve and filter azimuthal fluctuations in the

Efficient Modeling of Laser-Plasma Accelerators with INF&RNO

DOE Office of Scientific and Technical Information (OSTI.GOV)

Benedetti, C.; Schroeder, C. B.; Esarey, E.

2010-06-01

The numerical modeling code INF&RNO (INtegrated Fluid& paRticle simulatioN cOde, pronounced"inferno") is presented. INF&RNO is an efficient 2D cylindrical code to model the interaction of a short laser pulse with an underdense plasma. The code is based on an envelope model for the laser while either a PIC or a fluid description can be used for the plasma. The effect of the laser pulse on the plasma is modeled with the time-averaged poderomotive force. These and other features allow for a speedup of 2-4 orders of magnitude compared to standard full PIC simulations while still retaining physical fidelity. The codemore » has been benchmarked against analytical solutions and 3D PIC simulations and here a set of validation tests together with a discussion of the performances are presented.« less

Design and Control of Omnidirectional Unmanned Ground Vehicles for Rough Terrain

DTIC Science & Technology

2012-08-29

company, Quantum Signal. This rigid body dynamics simulation, housed within the Autonomous Navigation and Virtual Environment Laboratory (ANVEL) software...72 Figure 22: PIC main code. Page 24 of 72 Figure 23: PIC interrupt code. 3.3 Central Body Embedded Electronics As described above...located on the main body of the vehicle. This section describes how the on-board electronics works. The outline of the code is presented as is how

PIC codes for plasma accelerators on emerging computer architectures (GPUS, Multicore/Manycore CPUS)

NASA Astrophysics Data System (ADS)

Vincenti, Henri

2016-03-01

The advent of exascale computers will enable 3D simulations of a new laser-plasma interaction regimes that were previously out of reach of current Petasale computers. However, the paradigm used to write current PIC codes will have to change in order to fully exploit the potentialities of these new computing architectures. Indeed, achieving Exascale computing facilities in the next decade will be a great challenge in terms of energy consumption and will imply hardware developments directly impacting our way of implementing PIC codes. As data movement (from die to network) is by far the most energy consuming part of an algorithm future computers will tend to increase memory locality at the hardware level and reduce energy consumption related to data movement by using more and more cores on each compute nodes (''fat nodes'') that will have a reduced clock speed to allow for efficient cooling. To compensate for frequency decrease, CPU machine vendors are making use of long SIMD instruction registers that are able to process multiple data with one arithmetic operator in one clock cycle. SIMD register length is expected to double every four years. GPU's also have a reduced clock speed per core and can process Multiple Instructions on Multiple Datas (MIMD). At the software level Particle-In-Cell (PIC) codes will thus have to achieve both good memory locality and vectorization (for Multicore/Manycore CPU) to fully take advantage of these upcoming architectures. In this talk, we present the portable solutions we implemented in our high performance skeleton PIC code PICSAR to both achieve good memory locality and cache reuse as well as good vectorization on SIMD architectures. We also present the portable solutions used to parallelize the Pseudo-sepctral quasi-cylindrical code FBPIC on GPUs using the Numba python compiler.

Injection of externally produced kinetic electrons into a self-guided laser wakefield accelerator

NASA Astrophysics Data System (ADS)

Pollock, Bradley; Ralph, Joseph; Albert, Felicie; Shaw, Jessica; Clayton, Christopher; Marsh, Ken; Joshi, Chan; Mori, Warren; Kesler, Leigh; Mills, Sarah; Severson, Brian; Rigby, Alexandra; Glenzer, Siegfried

2012-10-01

A two-stage laser wakefield accelerator is being developed at the Lawrence Livermore National Laboratory using the Callisto laser system. The first stage is a high density (˜10^19 cm-3), 5 mm He gas jet plasma which is driven by 30 TW of 800 nm laser light focused to an a0˜ 2. The <100 MeV electrons produced in this stage are deflected by a 0.5 T dipole magnet onto the axis of the second stage, which is a low density (˜10^18 cm-3), 15 mm He gas cell driven by 200 TW of 800 nm light also focused to an a0˜ 2; no additional electrons are trapped in this stage. Electrons injected into the second stage can then be further accelerated to higher energy without increasing the energy spread. Measurements of the transmitted laser profile and spectrum from the second stage indicate that the laser pulse is self-guided throughout the gas cell and that a strong wake is driven. These results compare well with particle-in-cell (PIC) simulations performed with the code OSIRIS. This work was performed under the auspices of the United States Department of Energy by the Lawrence Livermore National Laboratory under contract No. DE-AC52-07NA-27344.

Fusion PIC code performance analysis on the Cori KNL system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Koskela, Tuomas S.; Deslippe, Jack; Friesen, Brian

We study the attainable performance of Particle-In-Cell codes on the Cori KNL system by analyzing a miniature particle push application based on the fusion PIC code XGC1. We start from the most basic building blocks of a PIC code and build up the complexity to identify the kernels that cost the most in performance and focus optimization efforts there. Particle push kernels operate at high AI and are not likely to be memory bandwidth or even cache bandwidth bound on KNL. Therefore, we see only minor benefits from the high bandwidth memory available on KNL, and achieving good vectorization ismore » shown to be the most beneficial optimization path with theoretical yield of up to 8x speedup on KNL. In practice we are able to obtain up to a 4x gain from vectorization due to limitations set by the data layout and memory latency.« less

Enhanced quasi-static particle-in-cell simulation of electron cloud instabilities in circular accelerators

NASA Astrophysics Data System (ADS)

Feng, Bing

Electron cloud instabilities have been observed in many circular accelerators around the world and raised concerns of future accelerators and possible upgrades. In this thesis, the electron cloud instabilities are studied with the quasi-static particle-in-cell (PIC) code QuickPIC. Modeling in three-dimensions the long timescale propagation of beam in electron clouds in circular accelerators requires faster and more efficient simulation codes. Thousands of processors are easily available for parallel computations. However, it is not straightforward to increase the effective speed of the simulation by running the same problem size on an increasingly number of processors because there is a limit to domain size in the decomposition of the two-dimensional part of the code. A pipelining algorithm applied on the fully parallelized particle-in-cell code QuickPIC is implemented to overcome this limit. The pipelining algorithm uses multiple groups of processors and optimizes the job allocation on the processors in parallel computing. With this novel algorithm, it is possible to use on the order of 102 processors, and to expand the scale and the speed of the simulation with QuickPIC by a similar factor. In addition to the efficiency improvement with the pipelining algorithm, the fidelity of QuickPIC is enhanced by adding two physics models, the beam space charge effect and the dispersion effect. Simulation of two specific circular machines is performed with the enhanced QuickPIC. First, the proposed upgrade to the Fermilab Main Injector is studied with an eye upon guiding the design of the upgrade and code validation. Moderate emittance growth is observed for the upgrade of increasing the bunch population by 5 times. But the simulation also shows that increasing the beam energy from 8GeV to 20GeV or above can effectively limit the emittance growth. Then the enhanced QuickPIC is used to simulate the electron cloud effect on electron beam in the Cornell Energy Recovery Linac (ERL) due to extremely small emittance and high peak currents anticipated in the machine. A tune shift is discovered from the simulation; however, emittance growth of the electron beam in electron cloud is not observed for ERL parameters.

An electrostatic Particle-In-Cell code on multi-block structured meshes

NASA Astrophysics Data System (ADS)

Meierbachtol, Collin S.; Svyatskiy, Daniil; Delzanno, Gian Luca; Vernon, Louis J.; Moulton, J. David

2017-12-01

We present an electrostatic Particle-In-Cell (PIC) code on multi-block, locally structured, curvilinear meshes called Curvilinear PIC (CPIC). Multi-block meshes are essential to capture complex geometries accurately and with good mesh quality, something that would not be possible with single-block structured meshes that are often used in PIC and for which CPIC was initially developed. Despite the structured nature of the individual blocks, multi-block meshes resemble unstructured meshes in a global sense and introduce several new challenges, such as the presence of discontinuities in the mesh properties and coordinate orientation changes across adjacent blocks, and polyjunction points where an arbitrary number of blocks meet. In CPIC, these challenges have been met by an approach that features: (1) a curvilinear formulation of the PIC method: each mesh block is mapped from the physical space, where the mesh is curvilinear and arbitrarily distorted, to the logical space, where the mesh is uniform and Cartesian on the unit cube; (2) a mimetic discretization of Poisson's equation suitable for multi-block meshes; and (3) a hybrid (logical-space position/physical-space velocity), asynchronous particle mover that mitigates the performance degradation created by the necessity to track particles as they move across blocks. The numerical accuracy of CPIC was verified using two standard plasma-material interaction tests, which demonstrate good agreement with the corresponding analytic solutions. Compared to PIC codes on unstructured meshes, which have also been used for their flexibility in handling complex geometries but whose performance suffers from issues associated with data locality and indirect data access patterns, PIC codes on multi-block structured meshes may offer the best compromise for capturing complex geometries while also maintaining solution accuracy and computational efficiency.

An electrostatic Particle-In-Cell code on multi-block structured meshes

DOE PAGES

Meierbachtol, Collin S.; Svyatskiy, Daniil; Delzanno, Gian Luca; ...

2017-09-14

We present an electrostatic Particle-In-Cell (PIC) code on multi-block, locally structured, curvilinear meshes called Curvilinear PIC (CPIC). Multi-block meshes are essential to capture complex geometries accurately and with good mesh quality, something that would not be possible with single-block structured meshes that are often used in PIC and for which CPIC was initially developed. In spite of the structured nature of the individual blocks, multi-block meshes resemble unstructured meshes in a global sense and introduce several new challenges, such as the presence of discontinuities in the mesh properties and coordinate orientation changes across adjacent blocks, and polyjunction points where anmore » arbitrary number of blocks meet. In CPIC, these challenges have been met by an approach that features: (1) a curvilinear formulation of the PIC method: each mesh block is mapped from the physical space, where the mesh is curvilinear and arbitrarily distorted, to the logical space, where the mesh is uniform and Cartesian on the unit cube; (2) a mimetic discretization of Poisson's equation suitable for multi-block meshes; and (3) a hybrid (logical-space position/physical-space velocity), asynchronous particle mover that mitigates the performance degradation created by the necessity to track particles as they move across blocks. The numerical accuracy of CPIC was verified using two standard plasma–material interaction tests, which demonstrate good agreement with the corresponding analytic solutions. And compared to PIC codes on unstructured meshes, which have also been used for their flexibility in handling complex geometries but whose performance suffers from issues associated with data locality and indirect data access patterns, PIC codes on multi-block structured meshes may offer the best compromise for capturing complex geometries while also maintaining solution accuracy and computational efficiency.« less

An electrostatic Particle-In-Cell code on multi-block structured meshes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meierbachtol, Collin S.; Svyatskiy, Daniil; Delzanno, Gian Luca

We present an electrostatic Particle-In-Cell (PIC) code on multi-block, locally structured, curvilinear meshes called Curvilinear PIC (CPIC). Multi-block meshes are essential to capture complex geometries accurately and with good mesh quality, something that would not be possible with single-block structured meshes that are often used in PIC and for which CPIC was initially developed. In spite of the structured nature of the individual blocks, multi-block meshes resemble unstructured meshes in a global sense and introduce several new challenges, such as the presence of discontinuities in the mesh properties and coordinate orientation changes across adjacent blocks, and polyjunction points where anmore » arbitrary number of blocks meet. In CPIC, these challenges have been met by an approach that features: (1) a curvilinear formulation of the PIC method: each mesh block is mapped from the physical space, where the mesh is curvilinear and arbitrarily distorted, to the logical space, where the mesh is uniform and Cartesian on the unit cube; (2) a mimetic discretization of Poisson's equation suitable for multi-block meshes; and (3) a hybrid (logical-space position/physical-space velocity), asynchronous particle mover that mitigates the performance degradation created by the necessity to track particles as they move across blocks. The numerical accuracy of CPIC was verified using two standard plasma–material interaction tests, which demonstrate good agreement with the corresponding analytic solutions. And compared to PIC codes on unstructured meshes, which have also been used for their flexibility in handling complex geometries but whose performance suffers from issues associated with data locality and indirect data access patterns, PIC codes on multi-block structured meshes may offer the best compromise for capturing complex geometries while also maintaining solution accuracy and computational efficiency.« less

Regolith X-Ray Imaging Spectrometer (REXIS) Aboard the OSIRIS-REx Asteroid Sample Return Mission

NASA Astrophysics Data System (ADS)

Masterson, R. A.; Chodas, M.; Bayley, L.; Allen, B.; Hong, J.; Biswas, P.; McMenamin, C.; Stout, K.; Bokhour, E.; Bralower, H.; Carte, D.; Chen, S.; Jones, M.; Kissel, S.; Schmidt, F.; Smith, M.; Sondecker, G.; Lim, L. F.; Lauretta, D. S.; Grindlay, J. E.; Binzel, R. P.

2018-02-01

The Regolith X-ray Imaging Spectrometer (REXIS) is the student collaboration experiment proposed and built by an MIT-Harvard team, launched aboard NASA's OSIRIS-REx asteroid sample return mission. REXIS complements the scientific investigations of other OSIRIS-REx instruments by determining the relative abundances of key elements present on the asteroid's surface by measuring the X-ray fluorescence spectrum (stimulated by the natural solar X-ray flux) over the range of energies 0.5 to 7 keV. REXIS consists of two components: a main imaging spectrometer with a coded aperture mask and a separate solar X-ray monitor to account for the Sun's variability. In addition to element abundance ratios (relative to Si) pinpointing the asteroid's most likely meteorite association, REXIS also maps elemental abundance variability across the asteroid's surface using the asteroid's rotation as well as the spacecraft's orbital motion. Image reconstruction at the highest resolution is facilitated by the coded aperture mask. Through this operation, REXIS will be the first application of X-ray coded aperture imaging to planetary surface mapping, making this student-built instrument a pathfinder toward future planetary exploration. To date, 60 students at the undergraduate and graduate levels have been involved with the REXIS project, with the hands-on experience translating to a dozen Master's and Ph.D. theses and other student publications.

Particle-in-cell simulations of bounded plasma discharges applied to low pressure high density sources and positive columns

NASA Astrophysics Data System (ADS)

Kawamura, Emi

Particle-in-cell (PIC) simulations of bounded plasma discharges are attractive because the fields and the particle motion can be obtained self-consistently from first principles. Thus, we can accurately model a wide range of nonlocal and kinetic behavior. The only disadvantage is that PIC may be computationally expensive compared to other methods. Fluid codes, for example, may run faster but make assumptions about the bulk plasma velocity distributions and ignore kinetic effects. In Chapter 1, we demonstrate methods of accelerating PIC simulations of bounded plasma discharges. We find that a combination of physical and numerical methods makes run-times for PIC codes much more competitive with other types of codes. In processing plasmas, the ion energy distributions (IEDs) arriving at the wafer target are crucial in determining ion anisotropy and etch rates. The current trend for plasma reactors is towards lower gas pressure and higher plasma density. In Chapter 2, we review and analyze IEDs arriving at the target of low pressure high density rf plasma reactors. In these reactors, the sheath is typically collisionless. We then perform PIC simulations of collisionless rf sheaths and find that the key parameter governing the shape of the TED at the wafer is the ratio of the ion transit time across the sheath over the rf period. Positive columns are the source of illumination in fluorescent mercury-argon lamps. The efficiency of light production increases with decreasing gas pressure and decreasing discharge radius. Most current lamp software is based on the local concept even though low pressure lighting discharges tend to be nonlocal. In Chapter 3, we demonstrate a 1d3v radial PIC model to conduct nonlocal kinetic simulations of low pressure, small radius positive columns. When compared to other available codes, we find that our PIC code makes the least approximations and assumptions and is accurate and stable over a wider parameter range. We analyze the PIC simulation results in detail and find that the radial electron heat flow, which is neglected in local models, plays a major role in maintaining the global power balance. In Chapter 2, we focused on the sheaths of low pressure high density plasma reactors. In Chapter 4, we extend our study to the bulk and presheaths. Typical industrial plasma reactors often use gases with complex chemistries which tend to generate discharges containing negative ions. For high density electronegative plasmas with low gas pressure, we expect Coulomb collisions between positive and negative ions to dominate over collisions between ions and neutrals. We incorporate a Coulomb collision model into our PIC code to study the effect of this ion-ion Coulomb scattering. We find that the Coulomb collisions between the positive and negative ions significantly modify the negative ion flux, density and kinetic energy profiles.

Development of an Implicit, Charge and Energy Conserving 2D Electromagnetic PIC Code on Advanced Architectures

NASA Astrophysics Data System (ADS)

Payne, Joshua; Taitano, William; Knoll, Dana; Liebs, Chris; Murthy, Karthik; Feltman, Nicolas; Wang, Yijie; McCarthy, Colleen; Cieren, Emanuel

2012-10-01

In order to solve problems such as the ion coalescence and slow MHD shocks fully kinetically we developed a fully implicit 2D energy and charge conserving electromagnetic PIC code, PlasmaApp2D. PlasmaApp2D differs from previous implicit PIC implementations in that it will utilize advanced architectures such as GPUs and shared memory CPU systems, with problems too large to fit into cache. PlasmaApp2D will be a hybrid CPU-GPU code developed primarily to run on the DARWIN cluster at LANL utilizing four 12-core AMD Opteron CPUs and two NVIDIA Tesla GPUs per node. MPI will be used for cross-node communication, OpenMP will be used for on-node parallelism, and CUDA will be used for the GPUs. Development progress and initial results will be presented.

Verification of long wavelength electromagnetic modes with a gyrokinetic-fluid hybrid model in the XGC code

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hager, Robert; Lang, Jianying; Chang, C. S.

As an alternative option to kinetic electrons, the gyrokinetic total-f particle-in-cell (PIC) code XGC1 has been extended to the MHD/fluid type electromagnetic regime by combining gyrokinetic PIC ions with massless drift-fluid electrons. Here, two representative long wavelength modes, shear Alfven waves and resistive tearing modes, are verified in cylindrical and toroidal magnetic field geometries.

Verification of long wavelength electromagnetic modes with a gyrokinetic-fluid hybrid model in the XGC code

DOE PAGES

Hager, Robert; Lang, Jianying; Chang, C. S.; ...

2017-05-24

As an alternative option to kinetic electrons, the gyrokinetic total-f particle-in-cell (PIC) code XGC1 has been extended to the MHD/fluid type electromagnetic regime by combining gyrokinetic PIC ions with massless drift-fluid electrons. Here, two representative long wavelength modes, shear Alfven waves and resistive tearing modes, are verified in cylindrical and toroidal magnetic field geometries.

Laser-plasma interactions with a Fourier-Bessel particle-in-cell method

DOE Office of Scientific and Technical Information (OSTI.GOV)

Andriyash, Igor A., E-mail: igor.andriyash@gmail.com; LOA, ENSTA ParisTech, CNRS, Ecole polytechnique, Université Paris-Saclay, 828 bd des Maréchaux, 91762 Palaiseau cedex; Lehe, Remi

A new spectral particle-in-cell (PIC) method for plasma modeling is presented and discussed. In the proposed scheme, the Fourier-Bessel transform is used to translate the Maxwell equations to the quasi-cylindrical spectral domain. In this domain, the equations are solved analytically in time, and the spatial derivatives are approximated with high accuracy. In contrast to the finite-difference time domain (FDTD) methods, that are used commonly in PIC, the developed method does not produce numerical dispersion and does not involve grid staggering for the electric and magnetic fields. These features are especially valuable in modeling the wakefield acceleration of particles in plasmas.more » The proposed algorithm is implemented in the code PLARES-PIC, and the test simulations of laser plasma interactions are compared to the ones done with the quasi-cylindrical FDTD PIC code CALDER-CIRC.« less

Rapid development of image analysis research tools: Bridging the gap between researcher and clinician with pyOsiriX.

PubMed

Blackledge, Matthew D; Collins, David J; Koh, Dow-Mu; Leach, Martin O

2016-02-01

We present pyOsiriX, a plugin built for the already popular dicom viewer OsiriX that provides users the ability to extend the functionality of OsiriX through simple Python scripts. This approach allows users to integrate the many cutting-edge scientific/image-processing libraries created for Python into a powerful DICOM visualisation package that is intuitive to use and already familiar to many clinical researchers. Using pyOsiriX we hope to bridge the apparent gap between basic imaging scientists and clinical practice in a research setting and thus accelerate the development of advanced clinical image processing. We provide arguments for the use of Python as a robust scripting language for incorporation into larger software solutions, outline the structure of pyOsiriX and how it may be used to extend the functionality of OsiriX, and we provide three case studies that exemplify its utility. For our first case study we use pyOsiriX to provide a tool for smooth histogram display of voxel values within a user-defined region of interest (ROI) in OsiriX. We used a kernel density estimation (KDE) method available in Python using the scikit-learn library, where the total number of lines of Python code required to generate this tool was 22. Our second example presents a scheme for segmentation of the skeleton from CT datasets. We have demonstrated that good segmentation can be achieved for two example CT studies by using a combination of Python libraries including scikit-learn, scikit-image, SimpleITK and matplotlib. Furthermore, this segmentation method was incorporated into an automatic analysis of quantitative PET-CT in a patient with bone metastases from primary prostate cancer. This enabled repeatable statistical evaluation of PET uptake values for each lesion, before and after treatment, providing estaimes maximum and median standardised uptake values (SUVmax and SUVmed respectively). Following treatment we observed a reduction in lesion volume, SUVmax and SUVmed for all lesions, in agreement with a reduction in concurrent measures of serum prostate-specific antigen (PSA). Crown Copyright © 2015. Published by Elsevier Ltd. All rights reserved.

Performance and capacity analysis of Poisson photon-counting based Iter-PIC OCDMA systems.

PubMed

Li, Lingbin; Zhou, Xiaolin; Zhang, Rong; Zhang, Dingchen; Hanzo, Lajos

2013-11-04

In this paper, an iterative parallel interference cancellation (Iter-PIC) technique is developed for optical code-division multiple-access (OCDMA) systems relying on shot-noise limited Poisson photon-counting reception. The novel semi-analytical tool of extrinsic information transfer (EXIT) charts is used for analysing both the bit error rate (BER) performance as well as the channel capacity of these systems and the results are verified by Monte Carlo simulations. The proposed Iter-PIC OCDMA system is capable of achieving two orders of magnitude BER improvements and a 0.1 nats of capacity improvement over the conventional chip-level OCDMA systems at a coding rate of 1/10.

Progress on the Development of the hPIC Particle-in-Cell Code

NASA Astrophysics Data System (ADS)

Dart, Cameron; Hayes, Alyssa; Khaziev, Rinat; Marcinko, Stephen; Curreli, Davide; Laboratory of Computational Plasma Physics Team

2017-10-01

Advancements were made in the development of the kinetic-kinetic electrostatic Particle-in-Cell code, hPIC, designed for large-scale simulation of the Plasma-Material Interface. hPIC achieved a weak scaling efficiency of 87% using the Algebraic Multigrid Solver BoomerAMG from the PETSc library on more than 64,000 cores of the Blue Waters supercomputer at the University of Illinois at Urbana-Champaign. The code successfully simulates two-stream instability and a volume of plasma over several square centimeters of surface extending out to the presheath in kinetic-kinetic mode. Results from a parametric study of the plasma sheath in strongly magnetized conditions will be presented, as well as a detailed analysis of the plasma sheath structure at grazing magnetic angles. The distribution function and its moments will be reported for plasma species in the simulation domain and at the material surface for plasma sheath simulations. Membership Pending.

Exploring Ultrahigh-Intensity Laser-Plasma Interaction Physics with QED Particle-in-Cell Simulations

NASA Astrophysics Data System (ADS)

Luedtke, S. V.; Yin, L.; Labun, L. A.; Albright, B. J.; Stark, D. J.; Bird, R. F.; Nystrom, W. D.; Hegelich, B. M.

2017-10-01

Next generation high-intensity lasers are reaching intensity regimes where new physics-quantum electrodynamics (QED) corrections to otherwise classical plasma dynamics-becomes important. Modeling laser-plasma interactions in these extreme settings presents a challenge to traditional particle-in-cell (PIC) codes, which either do not have radiation reaction or include only classical radiation reaction. We discuss a semi-classical approach to adding quantum radiation reaction and photon production to the PIC code VPIC. We explore these intensity regimes with VPIC, compare with results from the PIC code PSC, and report on ongoing work to expand the capability of VPIC in these regimes. This work was supported by the U.S. DOE, Los Alamos National Laboratory Science program, LDRD program, NNSA (DE-NA0002008), and AFOSR (FA9550-14-1-0045). HPC resources provided by TACC, XSEDE, and LANL Institutional Computing.

Boltzmann Transport in Hybrid PIC HET Modeling

DTIC Science & Technology

2015-07-01

Paper 3. DATES COVERED (From - To) July 2015-July 2015 4. TITLE AND SUBTITLE Boltzmann transport in hybrid PIC HET modeling 5a. CONTRACT NUMBER In...reproduce experimentally observed mobility trends derived from HPHall, a workhorse hybrid- PIC HET simulation code. 15. SUBJECT TERMS 16. SECURITY...CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT 18 . NUMBER OF PAGES 19a. NAME OF RESPONSIBLE PERSON Justin Koo a. REPORT Unclassified b. ABSTRACT

OSIRIS-REx Visible And Infrared Spectrometer - OVIRS

NASA Technical Reports Server (NTRS)

Hair, Jason

2016-01-01

Goddard Space Flight Center: Overall Instrument Responsibility; Instrument Scientist and Deputy Instrument Scientist; Management Systems Engineering; Mechanical Hardware; Harness Assemblies; SIDECAR Assembly Code; OVIRS Integration and Environmental Qualification; OVIRS Performance Testing, Calibration and Characterization.

Apar-T: code, validation, and physical interpretation of particle-in-cell results

NASA Astrophysics Data System (ADS)

Melzani, Mickaël; Winisdoerffer, Christophe; Walder, Rolf; Folini, Doris; Favre, Jean M.; Krastanov, Stefan; Messmer, Peter

2013-10-01

We present the parallel particle-in-cell (PIC) code Apar-T and, more importantly, address the fundamental question of the relations between the PIC model, the Vlasov-Maxwell theory, and real plasmas. First, we present four validation tests: spectra from simulations of thermal plasmas, linear growth rates of the relativistic tearing instability and of the filamentation instability, and nonlinear filamentation merging phase. For the filamentation instability we show that the effective growth rates measured on the total energy can differ by more than 50% from the linear cold predictions and from the fastest modes of the simulation. We link these discrepancies to the superparticle number per cell and to the level of field fluctuations. Second, we detail a new method for initial loading of Maxwell-Jüttner particle distributions with relativistic bulk velocity and relativistic temperature, and explain why the traditional method with individual particle boosting fails. The formulation of the relativistic Harris equilibrium is generalized to arbitrary temperature and mass ratios. Both are required for the tearing instability setup. Third, we turn to the key point of this paper and scrutinize the question of what description of (weakly coupled) physical plasmas is obtained by PIC models. These models rely on two building blocks: coarse-graining, i.e., grouping of the order of p ~ 1010 real particles into a single computer superparticle, and field storage on a grid with its subsequent finite superparticle size. We introduce the notion of coarse-graining dependent quantities, i.e., quantities depending on p. They derive from the PIC plasma parameter ΛPIC, which we show to behave as ΛPIC ∝ 1/p. We explore two important implications. One is that PIC collision- and fluctuation-induced thermalization times are expected to scale with the number of superparticles per grid cell, and thus to be a factor p ~ 1010 smaller than in real plasmas, a fact that we confirm with simulations. The other is that the level of electric field fluctuations scales as 1/ΛPIC ∝ p. We provide a corresponding exact expression, taking into account the finite superparticle size. We confirm both expectations with simulations. Fourth, we compare the Vlasov-Maxwell theory, often used for code benchmarking, to the PIC model. The former describes a phase-space fluid with Λ = + ∞ and no correlations, while the PIC plasma features a small Λ and a high level of correlations when compared to a real plasma. These differences have to be kept in mind when interpreting and validating PIC results against the Vlasov-Maxwell theory and when modeling real physical plasmas.

High-Speed Particle-in-Cell Simulation Parallelized with Graphic Processing Units for Low Temperature Plasmas for Material Processing

NASA Astrophysics Data System (ADS)

Hur, Min Young; Verboncoeur, John; Lee, Hae June

2014-10-01

Particle-in-cell (PIC) simulations have high fidelity in the plasma device requiring transient kinetic modeling compared with fluid simulations. It uses less approximation on the plasma kinetics but requires many particles and grids to observe the semantic results. It means that the simulation spends lots of simulation time in proportion to the number of particles. Therefore, PIC simulation needs high performance computing. In this research, a graphic processing unit (GPU) is adopted for high performance computing of PIC simulation for low temperature discharge plasmas. GPUs have many-core processors and high memory bandwidth compared with a central processing unit (CPU). NVIDIA GeForce GPUs were used for the test with hundreds of cores which show cost-effective performance. PIC code algorithm is divided into two modules which are a field solver and a particle mover. The particle mover module is divided into four routines which are named move, boundary, Monte Carlo collision (MCC), and deposit. Overall, the GPU code solves particle motions as well as electrostatic potential in two-dimensional geometry almost 30 times faster than a single CPU code. This work was supported by the Korea Institute of Science Technology Information.

Spacecraft charging analysis with the implicit particle-in-cell code iPic3D

DOE Office of Scientific and Technical Information (OSTI.GOV)

Deca, J.; Lapenta, G.; Marchand, R.

2013-10-15

We present the first results on the analysis of spacecraft charging with the implicit particle-in-cell code iPic3D, designed for running on massively parallel supercomputers. The numerical algorithm is presented, highlighting the implementation of the electrostatic solver and the immersed boundary algorithm; the latter which creates the possibility to handle complex spacecraft geometries. As a first step in the verification process, a comparison is made between the floating potential obtained with iPic3D and with Orbital Motion Limited theory for a spherical particle in a uniform stationary plasma. Second, the numerical model is verified for a CubeSat benchmark by comparing simulation resultsmore » with those of PTetra for space environment conditions with increasing levels of complexity. In particular, we consider spacecraft charging from plasma particle collection, photoelectron and secondary electron emission. The influence of a background magnetic field on the floating potential profile near the spacecraft is also considered. Although the numerical approaches in iPic3D and PTetra are rather different, good agreement is found between the two models, raising the level of confidence in both codes to predict and evaluate the complex plasma environment around spacecraft.« less

Numerical simulation of ion charge breeding in electron beam ion source

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhao, L., E-mail: zhao@far-tech.com; Kim, Jin-Soo

2014-02-15

The Electron Beam Ion Source particle-in-cell code (EBIS-PIC) tracks ions in an EBIS electron beam while updating electric potential self-consistently and atomic processes by the Monte Carlo method. Recent improvements to the code are reported in this paper. The ionization module has been improved by using experimental ionization energies and shell effects. The acceptance of injected ions and the emittance of extracted ion beam are calculated by extending EBIS-PIC to the beam line transport region. An EBIS-PIC simulation is performed for a Cs charge-breeding experiment at BNL. The charge state distribution agrees well with experiments, and additional simulation results ofmore » radial profiles and velocity space distributions of the trapped ions are presented.« less

3D PIC SIMULATIONS OF COLLISIONLESS SHOCKS AT LUNAR MAGNETIC ANOMALIES AND THEIR ROLE IN FORMING LUNAR SWIRLS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bamford, R. A.; Kellett, B. J.; Alves, E. P.

Investigation of the lunar crustal magnetic anomalies offers a comprehensive long-term data set of observations of small-scale magnetic fields and their interaction with the solar wind. In this paper a review of the observations of lunar mini-magnetospheres is compared quantifiably with theoretical kinetic-scale plasma physics and 3D particle-in-cell simulations. The aim of this paper is to provide a complete picture of all the aspects of the phenomena and to show how the observations from all the different and international missions interrelate. The analysis shows that the simulations are consistent with the formation of miniature (smaller than the ion Larmor orbit)more » collisionless shocks and miniature magnetospheric cavities, which has not been demonstrated previously. The simulations reproduce the finesse and form of the differential proton patterns that are believed to be responsible for the creation of both the “lunar swirls” and “dark lanes.” Using a mature plasma physics code like OSIRIS allows us, for the first time, to make a side-by-side comparison between model and space observations. This is shown for all of the key plasma parameters observed to date by spacecraft, including the spectral imaging data of the lunar swirls. The analysis of miniature magnetic structures offers insight into multi-scale mechanisms and kinetic-scale aspects of planetary magnetospheres.« less

Large Scale Earth's Bow Shock with Northern IMF as Simulated by PIC Code in Parallel with MHD Model

NASA Astrophysics Data System (ADS)

Baraka, Suleiman

2016-06-01

In this paper, we propose a 3D kinetic model (particle-in-cell, PIC) for the description of the large scale Earth's bow shock. The proposed version is stable and does not require huge or extensive computer resources. Because PIC simulations work with scaled plasma and field parameters, we also propose to validate our code by comparing its results with the available MHD simulations under same scaled solar wind (SW) and (IMF) conditions. We report new results from the two models. In both codes the Earth's bow shock position is found to be ≈14.8 R E along the Sun-Earth line, and ≈29 R E on the dusk side. Those findings are consistent with past in situ observations. Both simulations reproduce the theoretical jump conditions at the shock. However, the PIC code density and temperature distributions are inflated and slightly shifted sunward when compared to the MHD results. Kinetic electron motions and reflected ions upstream may cause this sunward shift. Species distributions in the foreshock region are depicted within the transition of the shock (measured ≈2 c/ ω pi for Θ Bn = 90° and M MS = 4.7) and in the downstream. The size of the foot jump in the magnetic field at the shock is measured to be (1.7 c/ ω pi ). In the foreshocked region, the thermal velocity is found equal to 213 km s-1 at 15 R E and is equal to 63 km s -1 at 12 R E (magnetosheath region). Despite the large cell size of the current version of the PIC code, it is powerful to retain macrostructure of planets magnetospheres in very short time, thus it can be used for pedagogical test purposes. It is also likely complementary with MHD to deepen our understanding of the large scale magnetosphere.

Particle In Cell Codes on Highly Parallel Architectures

NASA Astrophysics Data System (ADS)

Tableman, Adam

2014-10-01

We describe strategies and examples of Particle-In-Cell Codes running on Nvidia GPU and Intel Phi architectures. This includes basic implementations in skeletons codes and full-scale development versions (encompassing 1D, 2D, and 3D codes) in Osiris. Both the similarities and differences between Intel's and Nvidia's hardware will be examined. Work supported by grants NSF ACI 1339893, DOE DE SC 000849, DOE DE SC 0008316, DOE DE NA 0001833, and DOE DE FC02 04ER 54780.

Verification of long wavelength electromagnetic modes with a gyrokinetic-fluid hybrid model in the XGC code

PubMed Central

Lang, Jianying; Ku, S.; Chen, Y.; Parker, S. E.; Adams, M. F.

2017-01-01

As an alternative option to kinetic electrons, the gyrokinetic total-f particle-in-cell (PIC) code XGC1 has been extended to the MHD/fluid type electromagnetic regime by combining gyrokinetic PIC ions with massless drift-fluid electrons analogous to Chen and Parker [Phys. Plasmas 8, 441 (2001)]. Two representative long wavelength modes, shear Alfvén waves and resistive tearing modes, are verified in cylindrical and toroidal magnetic field geometries. PMID:29104419

Particle-in-cell simulations with charge-conserving current deposition on graphic processing units

NASA Astrophysics Data System (ADS)

Ren, Chuang; Kong, Xianglong; Huang, Michael; Decyk, Viktor; Mori, Warren

2011-10-01

Recently using CUDA, we have developed an electromagnetic Particle-in-Cell (PIC) code with charge-conserving current deposition for Nvidia graphic processing units (GPU's) (Kong et al., Journal of Computational Physics 230, 1676 (2011). On a Tesla M2050 (Fermi) card, the GPU PIC code can achieve a one-particle-step process time of 1.2 - 3.2 ns in 2D and 2.3 - 7.2 ns in 3D, depending on plasma temperatures. In this talk we will discuss novel algorithms for GPU-PIC including charge-conserving current deposition scheme with few branching and parallel particle sorting. These algorithms have made efficient use of the GPU shared memory. We will also discuss how to replace the computation kernels of existing parallel CPU codes while keeping their parallel structures. This work was supported by U.S. Department of Energy under Grant Nos. DE-FG02-06ER54879 and DE-FC02-04ER54789 and by NSF under Grant Nos. PHY-0903797 and CCF-0747324.

A spectral, quasi-cylindrical and dispersion-free Particle-In-Cell algorithm

DOE PAGES

Lehe, Remi; Kirchen, Manuel; Andriyash, Igor A.; ...

2016-02-17

We propose a spectral Particle-In-Cell (PIC) algorithm that is based on the combination of a Hankel transform and a Fourier transform. For physical problems that have close-to-cylindrical symmetry, this algorithm can be much faster than full 3D PIC algorithms. In addition, unlike standard finite-difference PIC codes, the proposed algorithm is free of spurious numerical dispersion, in vacuum. This algorithm is benchmarked in several situations that are of interest for laser-plasma interactions. These benchmarks show that it avoids a number of numerical artifacts, that would otherwise affect the physics in a standard PIC algorithm - including the zero-order numerical Cherenkov effect.

Accidental pharmacological poisonings in young children: population-based study in three settings.

PubMed

Bell, Jane C; Bentley, Jason P; Downie, Catriona; Cairns, Rose; Buckley, Nicholas A; Katelaris, Annette; Pearson, Sallie-Anne; Nassar, Natasha

2018-01-15

Pharmacological poisonings in young children are avoidable. Previous studies report calls to poisons centres, presentations to emergency departments (ED) or hospital admissions. There are limited data assessing concurrent management of poisonings across all three settings. We aimed to describe accidental pharmacological poisonings in young children across our Poisons Information Centre (PIC), EDs and hospitals. A population-based study in New South Wales, Australia, of PIC calls, ED presentations and hospital admissions for accidental pharmacological poisoning in children aged <5 years, 2007-2013. We examined trends, medicines responsible and subsequent management. Medicines were coded using ICD10-AM diagnosis codes (T36-50). Over 2007-2013, pharmacological poisonings accounted for 67,816 PIC calls, 7739 ED presentations and 2082 admissions. Rates (per 10,000 children) of PIC calls declined from 220 to 178; ED presentations were stable (∼22-24), with a decrease in emergency cases offset by an increase in semi- or non-urgent presentations; hospital admissions declined (8-5). Most PIC calls related to "non-opioid analgesics" (25%), and "topical agents" (18%). Nearly every day, one child aged <5 years was admitted to hospital for poisoning. "Benzodiazepines", "other and unspecified antidepressants", "uncategorised antihypertensives", and "4-aminophenol derivatives" accounted for over one-third of all admissions. Most PIC calls (90%) were advised to stay home, 6% referred to hospital. One-quarter of ED presentations resulted in admission. Poisonings reported to PIC and hospitals declined, however, non-urgent ED presentations increased. Strategies to reduce therapeutic errors and access to medicines, and education campaigns to improve Poisons Centre call rates to prevent unnecessary ED presentations are needed.

Optimizing fusion PIC code performance at scale on Cori Phase 2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Koskela, T. S.; Deslippe, J.

In this paper we present the results of optimizing the performance of the gyrokinetic full-f fusion PIC code XGC1 on the Cori Phase Two Knights Landing system. The code has undergone substantial development to enable the use of vector instructions in its most expensive kernels within the NERSC Exascale Science Applications Program. We study the single-node performance of the code on an absolute scale using the roofline methodology to guide optimization efforts. We have obtained 2x speedups in single node performance due to enabling vectorization and performing memory layout optimizations. On multiple nodes, the code is shown to scale wellmore » up to 4000 nodes, near half the size of the machine. We discuss some communication bottlenecks that were identified and resolved during the work.« less

Engineering design of the Regolith X-ray Imaging Spectrometer (REXIS) instrument: an OSIRIS-REx student collaboration

NASA Astrophysics Data System (ADS)

Jones, Michael; Chodas, Mark; Smith, Matthew J.; Masterson, Rebecca A.

2014-07-01

OSIRIS-REx is a NASA New Frontiers mission scheduled for launch in 2016 that will travel to the asteroid Bennu and return a pristine sample of the asteroid to Earth. The REgolith X-ray Imaging Spectrometer (REXIS) is a student collaboration instrument on-board the OSIRIS-REx spacecraft. REXIS is a NASA risk Class D instrument, and its design and development is largely student led. The engineering team consists of MIT graduate and undergraduate students and staff at the MIT Space Systems Laboratory. The primary goal of REXIS is the education of science and engineering students through participation in the development of light hardware. In light, REXIS will contribute to the mission by providing an elemental abundance map of the asteroid and by characterizing Bennu among the known meteorite groups. REXIS is sensitive to X-rays between 0.5 and 7 keV, and uses coded aperture imaging to map the distribution of iron with 50 m spatial resolution. This paper describes the science goals, concept of operations, and overall engineering design of the REXIS instrument. Each subsystem of the instrument is addressed with a high-level description of the design. Critical design elements such as the Thermal Isolation Layer (TIL), radiation cover, coded-aperture mask, and Detector Assembly Mount (DAM) are discussed in further detail.

Quasi-static modeling of beam-plasma and laser-plasma interactions

NASA Astrophysics Data System (ADS)

Huang, Chengkun

Plasma wave wakefields excited by either laser or particle beams can sustain acceleration gradients three orders of magnitude larger than conventional RF accelerators. They are promising for accelerating particles in short distances for applications such as future high-energy colliders, and medical and industrial accelerators. In a Plasma Wakefield Accelerator (PWFA) or a Laser Wakefield Accelerator (LWFA), an intense particle or laser beam drives a plasma wave and generates a strong wakefield which has a phase velocity equal to the velocity of the driver. This wakefield can then be used to accelerate part of the drive beam or a separate trailing beam. The interaction between the plasma and the driver is highly nonlinear and therefore a particle description is required for computer modeling. A highly efficient, fully parallelized, fully relativistic, three-dimensional particle-in-cell code called QuickPIC for simulating plasma and laser wakefield acceleration has been developed. The model is based on the quasi-static or frozen field approximation, which assumes that the drive beam and/or the laser does not evolve during the time it takes for it to pass a plasma particle. The electromagnetic fields of the plasma wake and its associated index of refraction are then used to evolve the driver using very large time steps. This algorithm reduces the computational time by at least 2 to 3 orders of magnitude. Comparison between the new algorithm and a fully explicit model (OSIRIS) are presented. The agreement is excellent for problems of interest. Direction for future work is also discussed. QuickPIC has been used to study the "afterburner" concept. In this concept a fraction of an existing high-energy beam is separated out and used as a trailing beam with the goal that the trailing beam acquires at least twice the energy of the drive beam. Several critical issues such as the efficient transfer of energy and the stable propagation of both the drive and trailing beams in the plasma are investigated. We have simulated a 100 GeV and a 1 TeV plasma "afterburner" stages for electron beams and the results are presented. QuickPIC also has enabled us to develop a new theory for understanding the hosing instability of the drive and trailing beams. The new theory is based on a perturbation to the ion column boundary which includes relativistic effects, axial motion and the full electromagnetic character of the wake. The new theory is verified by comparing it to the simulation results. In the adiabatic long beam limit it recovers the result of previous work from fluid models.

Particle in cell/Monte Carlo collision analysis of the problem of identification of impurities in the gas by the plasma electron spectroscopy method

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kusoglu Sarikaya, C.; Rafatov, I., E-mail: rafatov@metu.edu.tr; Kudryavtsev, A. A.

2016-06-15

The work deals with the Particle in Cell/Monte Carlo Collision (PIC/MCC) analysis of the problem of detection and identification of impurities in the nonlocal plasma of gas discharge using the Plasma Electron Spectroscopy (PLES) method. For this purpose, 1d3v PIC/MCC code for numerical simulation of glow discharge with nonlocal electron energy distribution function is developed. The elastic, excitation, and ionization collisions between electron-neutral pairs and isotropic scattering and charge exchange collisions between ion-neutral pairs and Penning ionizations are taken into account. Applicability of the numerical code is verified under the Radio-Frequency capacitively coupled discharge conditions. The efficiency of the codemore » is increased by its parallelization using Open Message Passing Interface. As a demonstration of the PLES method, parallel PIC/MCC code is applied to the direct current glow discharge in helium doped with a small amount of argon. Numerical results are consistent with the theoretical analysis of formation of nonlocal EEDF and existing experimental data.« less

REgolith X-Ray Imaging Spectrometer (REXIS) Aboard NASA’s OSIRIS-REx Mission

NASA Astrophysics Data System (ADS)

Hong, JaeSub; Allen, Branden; Grindlay, Jonathan E.; Binzel, Richard P.; Masterson, Rebecca; Inamdar, Niraj K; Chodas, Mark; Smith, Matthew W; Bautz, Mark W.; Kissel, Steven E; Villasenor, Jesus Noel; Oprescu, Antonia

2014-06-01

The REgolith X-Ray Imaging Spectrometer (REXIS) is a student-led instrument being designed, built, and operated as a collaborative effort involving MIT and Harvard. It is a part of NASA's OSIRIS-REx mission, which is scheduled for launch in September of 2016 for a rendezvous with, and collection of a sample from the surface of the primitive carbonaceous chondrite-like asteroid 101955 Bennu in 2019. REXIS will determine spatial variations in elemental composition of Bennu's surface through solar-induced X-ray fluorescence. REXIS consists of four X-ray CCDs in the detector plane and an X-ray mask. It is the first coded-aperture X-ray telescope in a planetary mission, which combines the benefit of high X-ray throughput of wide-field collimation with imaging capability of a coded-mask, enabling detection of elemental surface distributions at approximately 50-200 m scales. We present an overview of the REXIS instrument and the expected performance.

Developing Chemistry and Kinetic Modeling Tools for Low-Temperature Plasma Simulations

NASA Astrophysics Data System (ADS)

Jenkins, Thomas; Beckwith, Kris; Davidson, Bradley; Kruger, Scott; Pankin, Alexei; Roark, Christine; Stoltz, Peter

2015-09-01

We discuss the use of proper orthogonal decomposition (POD) methods in VSim, a FDTD plasma simulation code capable of both PIC/MCC and fluid modeling. POD methods efficiently generate smooth representations of noisy self-consistent or test-particle PIC data, and are thus advantageous in computing macroscopic fluid quantities from large PIC datasets (e.g. for particle-based closure computations) and in constructing optimal visual representations of the underlying physics. They may also confer performance advantages for massively parallel simulations, due to the significant reduction in dataset sizes conferred by truncated singular-value decompositions of the PIC data. We also demonstrate how complex LTP chemistry scenarios can be modeled in VSim via an interface with MUNCHKIN, a developing standalone python/C++/SQL code that identifies reaction paths for given input species, solves 1D rate equations for the time-dependent chemical evolution of the system, and generates corresponding VSim input blocks with appropriate cross-sections/reaction rates. MUNCHKIN also computes reaction rates from user-specified distribution functions, and conducts principal path analyses to reduce the number of simulated chemical reactions. Supported by U.S. Department of Energy SBIR program, Award DE-SC0009501.

SHARP: A Spatially Higher-order, Relativistic Particle-in-cell Code

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shalaby, Mohamad; Broderick, Avery E.; Chang, Philip

Numerical heating in particle-in-cell (PIC) codes currently precludes the accurate simulation of cold, relativistic plasma over long periods, severely limiting their applications in astrophysical environments. We present a spatially higher-order accurate relativistic PIC algorithm in one spatial dimension, which conserves charge and momentum exactly. We utilize the smoothness implied by the usage of higher-order interpolation functions to achieve a spatially higher-order accurate algorithm (up to the fifth order). We validate our algorithm against several test problems—thermal stability of stationary plasma, stability of linear plasma waves, and two-stream instability in the relativistic and non-relativistic regimes. Comparing our simulations to exact solutionsmore » of the dispersion relations, we demonstrate that SHARP can quantitatively reproduce important kinetic features of the linear regime. Our simulations have a superior ability to control energy non-conservation and avoid numerical heating in comparison to common second-order schemes. We provide a natural definition for convergence of a general PIC algorithm: the complement of physical modes captured by the simulation, i.e., those that lie above the Poisson noise, must grow commensurately with the resolution. This implies that it is necessary to simultaneously increase the number of particles per cell and decrease the cell size. We demonstrate that traditional ways for testing for convergence fail, leading to plateauing of the energy error. This new PIC code enables us to faithfully study the long-term evolution of plasma problems that require absolute control of the energy and momentum conservation.« less

Efficient modeling of laser-plasma accelerator staging experiments using INF&RNO

NASA Astrophysics Data System (ADS)

Benedetti, C.; Schroeder, C. B.; Geddes, C. G. R.; Esarey, E.; Leemans, W. P.

2017-03-01

The computational framework INF&RNO (INtegrated Fluid & paRticle simulatioN cOde) allows for fast and accurate modeling, in 2D cylindrical geometry, of several aspects of laser-plasma accelerator physics. In this paper, we present some of the new features of the code, including the quasistatic Particle-In-Cell (PIC)/fluid modality, and describe using different computational grids and time steps for the laser envelope and the plasma wake. These and other features allow for a speedup of several orders of magnitude compared to standard full 3D PIC simulations while still retaining physical fidelity. INF&RNO is used to support the experimental activity at the BELLA Center, and we will present an example of the application of the code to the laser-plasma accelerator staging experiment.

Monte Carlo simulation of ion-neutral charge exchange collisions and grid erosion in an ion thruster

NASA Technical Reports Server (NTRS)

Peng, Xiaohang; Ruyten, Wilhelmus M.; Keefer, Dennis

1991-01-01

A combined particle-in-cell (PIC)/Monte Carlo simulation model has been developed in which the PIC method is used to simulate the charge exchange collisions. It is noted that a number of features were reproduced correctly by this code, but that its assumption of two-dimensional axisymmetry for a single set of grid apertures precluded the reproduction of the most characteristic feature of actual test data; namely, the concentrated grid erosion at the geometric center of the hexagonal aperture array. The first results of a three-dimensional code, which takes into account the hexagonal symmetry of the grid, are presented. It is shown that, with this code, the experimentally observed erosion patterns are reproduced correctly, demonstrating explicitly the concentration of sputtering between apertures.

Turbulence dissipation challenge: particle-in-cell simulations

NASA Astrophysics Data System (ADS)

Roytershteyn, V.; Karimabadi, H.; Omelchenko, Y.; Germaschewski, K.

2015-12-01

We discuss application of three particle in cell (PIC) codes to the problems relevant to turbulence dissipation challenge. VPIC is a fully kinetic code extensively used to study a variety of diverse problems ranging from laboratory plasmas to astrophysics. PSC is a flexible fully kinetic code offering a variety of algorithms that can be advantageous to turbulence simulations, including high order particle shapes, dynamic load balancing, and ability to efficiently run on Graphics Processing Units (GPUs). Finally, HYPERS is a novel hybrid (kinetic ions+fluid electrons) code, which utilizes asynchronous time advance and a number of other advanced algorithms. We present examples drawn both from large-scale turbulence simulations and from the test problems outlined by the turbulence dissipation challenge. Special attention is paid to such issues as the small-scale intermittency of inertial range turbulence, mode content of the sub-proton range of scales, the formation of electron-scale current sheets and the role of magnetic reconnection, as well as numerical challenges of applying PIC codes to simulations of astrophysical turbulence.

Secure web-based invocation of large-scale plasma simulation codes

NASA Astrophysics Data System (ADS)

Dimitrov, D. A.; Busby, R.; Exby, J.; Bruhwiler, D. L.; Cary, J. R.

2004-12-01

We present our design and initial implementation of a web-based system for running, both in parallel and serial, Particle-In-Cell (PIC) codes for plasma simulations with automatic post processing and generation of visual diagnostics.

Electromagnetic plasma simulation in realistic geometries

NASA Astrophysics Data System (ADS)

Brandon, S.; Ambrosiano, J. J.; Nielsen, D.

1991-08-01

Particle-in-Cell (PIC) calculations have become an indispensable tool to model the nonlinear collective behavior of charged particle species in electromagnetic fields. Traditional finite difference codes, such as CONDOR (2-D) and ARGUS (3-D), are used extensively to design experiments and develop new concepts. A wide variety of physical processes can be modeled simply and efficiently by these codes. However, experiments have become more complex. Geometrical shapes and length scales are becoming increasingly more difficult to model. Spatial resolution requirements for the electromagnetic calculation force large grids and small time steps. Many hours of CRAY YMP time may be required to complete 2-D calculation -- many more for 3-D calculations. In principle, the number of mesh points and particles need only to be increased until all relevant physical processes are resolved. In practice, the size of a calculation is limited by the computer budget. As a result, experimental design is being limited by the ability to calculate, not by the experimenters ingenuity or understanding of the physical processes involved. Several approaches to meet these computational demands are being pursued. Traditional PIC codes continue to be the major design tools. These codes are being actively maintained, optimized, and extended to handle large and more complex problems. Two new formulations are being explored to relax the geometrical constraints of the finite difference codes. A modified finite volume test code, TALUS, uses a data structure compatible with that of standard finite difference meshes. This allows a basic conformal boundary/variable grid capability to be retrofitted to CONDOR. We are also pursuing an unstructured grid finite element code, MadMax. The unstructured mesh approach provides maximum flexibility in the geometrical model while also allowing local mesh refinement.

National Underground Mines Inventory

DTIC Science & Technology

1983-10-01

system is well designed to minimize water accumulation on the drift levels. In many areas, sufficient water has accumulated to make the use of boots a...four characters designate Field office. 17-18 State Code Pic 99 FIPS code for state in which minets located. 19-21 County Code Plc 999 FIPS code for... Designate a general product class based onSIC code. 28-29 Nine Type Plc 99 Natal/Nonmetal mine type code. Based on subunit operations code and canvass code

Issues and opportunities: beam simulations for heavy ion fusion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Friedman, A

1999-07-15

UCRL- JC- 134975 PREPRINT code offering 3- D, axisymmetric, and ''transverse slice'' (steady flow) geometries, with a hierarchy of models for the ''lattice'' of focusing, bending, and accelerating elements. Interactive and script- driven code steering is afforded through an interpreter interface. The code runs with good parallel scaling on the T3E. Detailed simulations of machine segments and of complete small experiments, as well as simplified full- system runs, have been carried out, partially benchmarking the code. A magnetoinductive model, with module impedance and multi- beam effects, is under study. experiments, including an injector scalable to multi- beam arrays, a high-more » current beam transport and acceleration experiment, and a scaled final- focusing experiment. These ''phase I'' projects are laying the groundwork for the next major step in HIF development, the Integrated Research Experiment (IRE). Simulations aimed directly at the IRE must enable us to: design a facility with maximum power on target at minimal cost; set requirements for hardware tolerances, beam steering, etc.; and evaluate proposed chamber propagation modes. Finally, simulations must enable us to study all issues which arise in the context of a fusion driver, and must facilitate the assessment of driver options. In all of this, maximum advantage must be taken of emerging terascale computer architectures, requiring an aggressive code development effort. An organizing principle should be pursuit of the goal of integrated and detailed source- to- target simulation. methods for analysis of the beam dynamics in the various machine concepts, using moment- based methods for purposes of design, waveform synthesis, steering algorithm synthesis, etc. Three classes of discrete- particle models should be coupled: (1) electrostatic/ magnetoinductive PIC simulations should track the beams from the source through the final- focusing optics, passing details of the time- dependent distribution function to (2) electromagnetic or magnetoinductive PIC or hybrid PIG/ fluid simulations in the fusion chamber (which would finally pass their particle trajectory information to the radiation- hydrodynamics codes used for target design); in parallel, (3) detailed PIC, delta- f, core/ test- particle, and perhaps continuum Vlasov codes should be used to study individual sections of the driver and chamber very carefully; consistency may be assured by linking data from the PIC sequence, and knowledge gained may feed back into that sequence.« less

Fully kinetic 3D simulations of the Hermean magnetosphere under realistic conditions: a new approach

NASA Astrophysics Data System (ADS)

Amaya, Jorge; Gonzalez-Herrero, Diego; Lembège, Bertrand; Lapenta, Giovanni

2017-04-01

Simulations of the magnetosphere of planets are usually performed using the MHD and the hybrid approaches. However, these two methods still rely on approximations for the computation of the pressure tensor, and require the neutrality of the plasma at every point of the domain by construction. These approximations undermine the role of electrons on the emergence of plasma features in the magnetosphere of planets. The high mobility of electrons, their characteristic time and space scales, and the lack of perfect neutrality, are the source of many observed phenomena in the magnetospheres, including the turbulence energy cascade, the magnetic reconnection, the particle acceleration in the shock front and the formation of current systems around the magnetosphere. Fully kinetic codes are extremely demanding of computing time, and have been unable to perform simulations of the full magnetosphere at the real scales of a planet with realistic plasma conditions. This is caused by two main reasons: 1) explicit codes must resolve the electron scales limiting the time and space discretisation, and 2) current versions of semi-implicit codes are unstable for cell sizes larger than a few Debye lengths. In this work we present new simulations performed with ECsim, an Energy Conserving semi-implicit method [1], that can overcome these two barriers. We compare the solutions obtained with ECsim with the solutions obtained by the classic semi-implicit code iPic3D [2]. The new simulations with ECsim demand a larger computational effort, but the time and space discretisations are larger than those in iPic3D allowing for a faster simulation time of the full planetary environment. The new code, ECsim, can reach a resolution allowing the capture of significant large scale physics without loosing kinetic electron information, such as wave-electron interaction and non-Maxwellian electron velocity distributions [3]. The code is able to better capture the thickness of the different boundary layers of the magnetosphere of Mercury. Electron kinetics are consistent with the spatial and temporal scale resolutions. Simulations are compared with measurements from the MESSENGER spacecraft showing a better fit when compared against the classic fully kinetic code iPic3D. These results show that the new generation of Energy Conserving semi-implicit codes can be used for an accurate analysis and interpretation of particle data from magnetospheric missions like BepiColombo and MMS, including electron velocity distributions and electron temperature anisotropies. [1] Lapenta, G. (2016). Exactly Energy Conserving Implicit Moment Particle in Cell Formulation. arXiv preprint arXiv:1602.06326. [2] Markidis, S., & Lapenta, G. (2010). Multi-scale simulations of plasma with iPIC3D. Mathematics and Computers in Simulation, 80(7), 1509-1519. [3] Lapenta, G., Gonzalez-Herrero, D., & Boella, E. (2016). Multiple scale kinetic simulations with the energy conserving semi implicit particle in cell (PIC) method. arXiv preprint arXiv:1612.08289.

Web Service Model for Plasma Simulations with Automatic Post Processing and Generation of Visual Diagnostics*

NASA Astrophysics Data System (ADS)

Exby, J.; Busby, R.; Dimitrov, D. A.; Bruhwiler, D.; Cary, J. R.

2003-10-01

We present our design and initial implementation of a web service model for running particle-in-cell (PIC) codes remotely from a web browser interface. PIC codes have grown significantly in complexity and now often require parallel execution on multiprocessor computers, which in turn requires sophisticated post-processing and data analysis. A significant amount of time and effort is required for a physicist to develop all the necessary skills, at the expense of actually doing research. Moreover, parameter studies with a computationally intensive code justify the systematic management of results with an efficient way to communicate them among a group of remotely located collaborators. Our initial implementation uses the OOPIC Pro code [1], Linux, Apache, MySQL, Python, and PHP. The Interactive Data Language is used for visualization. [1] D.L. Bruhwiler et al., Phys. Rev. ST-AB 4, 101302 (2001). * This work is supported by DOE grant # DE-FG02-03ER83857 and by Tech-X Corp. ** Also University of Colorado.

Localization of TFIIB binding regions using serial analysis of chromatin occupancy

PubMed Central

Yochum, Gregory S; Rajaraman, Veena; Cleland, Ryan; McWeeney, Shannon

2007-01-01

Background: RNA Polymerase II (RNAP II) is recruited to core promoters by the pre-initiation complex (PIC) of general transcription factors. Within the PIC, transcription factor for RNA polymerase IIB (TFIIB) determines the start site of transcription. TFIIB binding has not been localized, genome-wide, in metazoans. Serial analysis of chromatin occupancy (SACO) is an unbiased methodology used to empirically identify transcription factor binding regions. In this report, we use TFIIB and SACO to localize TFIIB binding regions across the rat genome. Results: A sample of the TFIIB SACO library was sequenced and 12,968 TFIIB genomic signature tags (GSTs) were assigned to the rat genome. GSTs are 20–22 base pair fragments that are derived from TFIIB bound chromatin. TFIIB localized to both non-protein coding and protein-coding loci. For 21% of the 1783 protein-coding genes in this sample of the SACO library, TFIIB binding mapped near the characterized 5' promoter that is upstream of the transcription start site (TSS). However, internal TFIIB binding positions were identified in 57% of the 1783 protein-coding genes. Internal positions are defined as those within an inclusive region greater than 2.5 kb downstream from the 5' TSS and 2.5 kb upstream from the transcription stop. We demonstrate that both TFIIB and TFIID (an additional component of PICs) bound to internal regions using chromatin immunoprecipitation (ChIP). The 5' cap of transcripts associated with internal TFIIB binding positions were identified using a cap-trapping assay. The 5' TSSs for internal transcripts were confirmed by primer extension. Additionally, an analysis of the functional annotation of mouse 3 (FANTOM3) databases indicates that internally initiated transcripts identified by TFIIB SACO in rat are conserved in mouse. Conclusion: Our findings that TFIIB binding is not restricted to the 5' upstream region indicates that the propensity for PIC to contribute to transcript diversity is far greater than previously appreciated. PMID:17997859

PIC simulations of conical magnetically insulated transmission line with LTD generator: Transition from self-limited to load-limited flow

NASA Astrophysics Data System (ADS)

Liu, Laqun; Wang, Huihui; Guo, Fan; Zou, Wenkang; Liu, Dagang

2017-04-01

Based on the 3-dimensional Particle-In-Cell (PIC) code CHIPIC3D, with a new circuit boundary algorithm we developed, a conical magnetically insulated transmission line (MITL) with a 1.0-MV linear transformer driver (LTD) is explored numerically. The values of switch jitter time of LTD are critical parameters for the system, which are difficult to be measured experimentally. In this paper, these values are obtained by comparing the PIC results with experimental data of large diode-gap MITL. By decreasing the diode gap, we find that all PIC results agree well with experimental data only if MITL works on self-limited flow no matter how large the diode gap is. However, when the diode gap decreases to a threshold, the self-limited flow would transfer to a load-limited flow. In this situation, PIC results no longer agree with experimental data anymore due to the anode plasma expansion in the diode load. This disagreement is used to estimate the plasma expansion speed.

The SAGE II/OSIRIS/OMPS-LP USask 2D Deseasonalized Anomaly Ozone Data Record for Use in Trend Analysis

NASA Astrophysics Data System (ADS)

Degenstein, D. A.; Bourassa, A. E.; Zawada, D.; Roth, C.; McLinden, C. A.

2017-12-01

The SAGE II/OSIRIS/OMPS-LP USask 2D ozone deseasonalized anomaly data record spans over three decades, from 1984 to the present, and has been used extensively for the determination of stratospheric ozone trends in the post Montreal Protocol era. Radiance measurements made by the three instruments have all been used to produce ozone data profiles whose native units are number density as a function of altitude. Therefore, during the merging process required to produce the extended data record it is not necessary to use meteorological data for unit conversion and all trends contained within the data record come directly from the data products themselves. Although the SAGE II occultation data record ended in 2005, both the OMPS-LP and OSIRIS limb scattered sunlight data records continue. OSIRIS has been in operation since 2001 and is well beyond its lifetime but OMPS-LP is scheduled for launch on future spacecraft so the data record should continue for many years, or even decades. It is also anticipated that SAGE III ISS data will be added to the existing record to further enhance its utility for trend analysis. This paper will outline the process used to produce the deseasonalized ozone anomaly data record detailing the issues associated with merging data records that have different biases and sampling characteristics. Issues associated with SAGE II and OSIRIS measurements that are made at different local times will also be discussed. Finally, this paper will present trend results produced using variations of the official LOTUS analysis code. These results cover an altitude range from the tropopause to 55 km and from 60 South to 60 North in ten-degree bins. It will be shown that the new OMPS-LP USask 2D data record is of excellent quality and can be used to extend the ozone data records for the purpose of trend analysis.

Load management strategy for Particle-In-Cell simulations in high energy particle acceleration

NASA Astrophysics Data System (ADS)

Beck, A.; Frederiksen, J. T.; Dérouillat, J.

2016-09-01

In the wake of the intense effort made for the experimental CILEX project, numerical simulation campaigns have been carried out in order to finalize the design of the facility and to identify optimal laser and plasma parameters. These simulations bring, of course, important insight into the fundamental physics at play. As a by-product, they also characterize the quality of our theoretical and numerical models. In this paper, we compare the results given by different codes and point out algorithmic limitations both in terms of physical accuracy and computational performances. These limitations are illustrated in the context of electron laser wakefield acceleration (LWFA). The main limitation we identify in state-of-the-art Particle-In-Cell (PIC) codes is computational load imbalance. We propose an innovative algorithm to deal with this specific issue as well as milestones towards a modern, accurate high-performance PIC code for high energy particle acceleration.

Electron acceleration in the Solar corona - 3D PiC code simulations of guide field reconnection

NASA Astrophysics Data System (ADS)

Alejandro Munoz Sepulveda, Patricio

2017-04-01

The efficient electron acceleration in the solar corona detected by means of hard X-ray emission is still not well understood. Magnetic reconnection through current sheets is one of the proposed production mechanisms of non-thermal electrons in solar flares. Previous works in this direction were based mostly on test particle calculations or 2D fully-kinetic PiC simulations. We have now studied the consequences of self-generated current-aligned instabilities on the electron acceleration mechanisms by 3D magnetic reconnection. For this sake, we carried out 3D Particle-in-Cell (PiC) code numerical simulations of force free reconnecting current sheets, appropriate for the description of the solar coronal plasmas. We find an efficient electron energization, evidenced by the formation of a non-thermal power-law tail with a hard spectral index smaller than -2 in the electron energy distribution function. We discuss and compare the influence of the parallel electric field versus the curvature and gradient drifts in the guiding-center approximation on the overall acceleration, and their dependence on different plasma parameters.

UNIPIC code for simulations of high power microwave devices

NASA Astrophysics Data System (ADS)

Wang, Jianguo; Zhang, Dianhui; Liu, Chunliang; Li, Yongdong; Wang, Yue; Wang, Hongguang; Qiao, Hailiang; Li, Xiaoze

2009-03-01

In this paper, UNIPIC code, a new member in the family of fully electromagnetic particle-in-cell (PIC) codes for simulations of high power microwave (HPM) generation, is introduced. In the UNIPIC code, the electromagnetic fields are updated using the second-order, finite-difference time-domain (FDTD) method, and the particles are moved using the relativistic Newton-Lorentz force equation. The convolutional perfectly matched layer method is used to truncate the open boundaries of HPM devices. To model curved surfaces and avoid the time step reduction in the conformal-path FDTD method, CP weakly conditional-stable FDTD (WCS FDTD) method which combines the WCS FDTD and CP-FDTD methods, is implemented. UNIPIC is two-and-a-half dimensional, is written in the object-oriented C++ language, and can be run on a variety of platforms including WINDOWS, LINUX, and UNIX. Users can use the graphical user's interface to create the geometric structures of the simulated HPM devices, or input the old structures created before. Numerical experiments on some typical HPM devices by using the UNIPIC code are given. The results are compared to those obtained from some well-known PIC codes, which agree well with each other.

Collaborative Research: Simulation of Beam-Electron Cloud Interactions in Circular Accelerators Using Plasma Models

DOE Office of Scientific and Technical Information (OSTI.GOV)

Katsouleas, Thomas; Decyk, Viktor

Final Report for grant DE-FG02-06ER54888, "Simulation of Beam-Electron Cloud Interactions in Circular Accelerators Using Plasma Models" Viktor K. Decyk, University of California, Los Angeles Los Angeles, CA 90095-1547 The primary goal of this collaborative proposal was to modify the code QuickPIC and apply it to study the long-time stability of beam propagation in low density electron clouds present in circular accelerators. The UCLA contribution to this collaborative proposal was in supporting the development of the pipelining scheme for the QuickPIC code, which extended the parallel scaling of this code by two orders of magnitude. The USC work was as describedmore » here the PhD research for Ms. Bing Feng, lead author in reference 2 below, who performed the research at USC under the guidance of the PI Tom Katsouleas and the collaboration of Dr. Decyk The QuickPIC code [1] is a multi-scale Particle-in-Cell (PIC) code. The outer 3D code contains a beam which propagates through a long region of plasma and evolves slowly. The plasma response to this beam is modeled by slices of a 2D plasma code. This plasma response then is fed back to the beam code, and the process repeats. The pipelining is based on the observation that once the beam has passed a 2D slice, its response can be fed back to the beam immediately without waiting for the beam to pass all the other slices. Thus independent blocks of 2D slices from different time steps can be running simultaneously. The major difficulty was when particles at the edges needed to communicate with other blocks. Two versions of the pipelining scheme were developed, for the the full quasi-static code and the other for the basic quasi-static code used by this e-cloud proposal. Details of the pipelining scheme were published in [2]. The new version of QuickPIC was able to run with more than 1,000 processors, and was successfully applied in modeling e-clouds by our collaborators in this proposal [3-8]. Jean-Luc Vay at Lawrence Berkeley National Lab later implemented a similar basic quasistatic scheme including pipelining in the code WARP [9] and found good to very good quantitative agreement between the two codes in modeling e-clouds. References [1] C. Huang, V. K. Decyk, C. Ren, M. Zhou, W. Lu, W. B. Mori, J. H. Cooley, T. M. Antonsen, Jr., and T. Katsouleas, "QUICKPIC: A highly efficient particle-in-cell code for modeling wakefield acceleration in plasmas," J. Computational Phys. 217, 658 (2006). [2] B. Feng, C. Huang, V. K. Decyk, W. B. Mori, P. Muggli, and T. Katsouleas, "Enhancing parallel quasi-static particle-in-cell simulations with a pipelining algorithm," J. Computational Phys, 228, 5430 (2009). [3] C. Huang, V. K. Decyk, M. Zhou, W. Lu, W. B. Mori, J. H. Cooley, T. M. Antonsen, Jr., and B. Feng, T. Katsouleas, J. Vieira, and L. O. Silva, "QUICKPIC: A highly efficient fully parallelized PIC code for plasma-based acceleration," Proc. of the SciDAC 2006 Conf., Denver, Colorado, June, 2006 [Journal of Physics: Conference Series, W. M. Tang, Editor, vol. 46, Institute of Physics, Bristol and Philadelphia, 2006], p. 190. [4] B. Feng, C. Huang, V. Decyk, W. B. Mori, T. Katsouleas, P. Muggli, "Enhancing Plasma Wakefield and E-cloud Simulation Performance Using a Pipelining Algorithm," Proc. 12th Workshop on Advanced Accelerator Concepts, Lake Geneva, WI, July, 2006, p. 201 [AIP Conf. Proceedings, vol. 877, Melville, NY, 2006]. [5] B. Feng, P. Muggli, T. Katsouleas, V. Decyk, C. Huang, and W. Mori, "Long Time Electron Cloud Instability Simulation Using QuickPIC with Pipelining Algorithm," Proc. of the 2007 Particle Accelerator Conference, Albuquerque, NM, June, 2007, p. 3615. [6] B. Feng, C. Huang, V. Decyk, W. B. Mori, G. H. Hoffstaetter, P. Muggli, T. Katsouleas, "Simulation of Electron Cloud Effects on Electron Beam at ERL with Pipelined QuickPIC," Proc. 13th Workshop on Advanced Accelerator Concepts, Santa Cruz, CA, July-August, 2008, p. 340 [AIP Conf. Proceedings, vol. 1086, Melville, NY, 2008]. [7] B. Feng, C. Huang, V. K. Decyk, W. B. Mori, P. Muggli, and T. Katsouleas, "Enhancing parallel quasi-static particle-in-cell simulations with a pipelining algorithm," J. Computational Phys, 228, 5430 (2009). [8] C. Huang, W. An, V. K. Decyk, W. Lu, W. B. Mori, F. S. Tsung, M. Tzoufras, S. Morshed, T. Antonsen, B. Feng, T. Katsouleas, R., A. Fonseca, S. F. Martins, J. Vieira, L. O. Silva, E. Esarey, C. G. R. Geddes, W. P. Leemans, E. Cormier-Michel, J.-L. Vay, D. L. Bruhwiler, B. Cowan, J. R. Cary, and K. Paul, "Recent results and future challenges for large scale particleion- cell simulations of plasma-based accelerator concepts," Proc. of the SciDAC 2009 Conf., San Diego, CA, June, 2009 [Journal of Physics: Conference Series, vol. 180, Institute of Physics, Bristol and Philadelphia, 2009], p. 012005. [9] J.-L. Vay, C. M. Celata, M. A. Furman, G. Penn, M. Venturini, D. P. Grote, and K. G. Sonnad, ?Update on Electron-Cloud Simulations Using the Package WARP-POSINST.? Proc. of the 2009 Particle Accelerator Conference PAC09, Vancouver, Canada, June, 2009, paper FR5RFP078.« less

A Particle Module for the PLUTO Code. I. An Implementation of the MHD–PIC Equations

NASA Astrophysics Data System (ADS)

Mignone, A.; Bodo, G.; Vaidya, B.; Mattia, G.

2018-05-01

We describe an implementation of a particle physics module available for the PLUTO code appropriate for the dynamical evolution of a plasma consisting of a thermal fluid and a nonthermal component represented by relativistic charged particles or cosmic rays (CRs). While the fluid is approached using standard numerical schemes for magnetohydrodynamics, CR particles are treated kinetically using conventional Particle-In-Cell (PIC) techniques. The module can be used either to describe test-particle motion in the fluid electromagnetic field or to solve the fully coupled magnetohydrodynamics (MHD)–PIC system of equations with particle backreaction on the fluid as originally introduced by Bai et al. Particle backreaction on the fluid is included in the form of momentum–energy feedback and by introducing the CR-induced Hall term in Ohm’s law. The hybrid MHD–PIC module can be employed to study CR kinetic effects on scales larger than the (ion) skin depth provided that the Larmor gyration scale is properly resolved. When applicable, this formulation avoids resolving microscopic scales, offering substantial computational savings with respect to PIC simulations. We present a fully conservative formulation that is second-order accurate in time and space, and extends to either the Runge–Kutta (RK) or the corner transport upwind time-stepping schemes (for the fluid), while a standard Boris integrator is employed for the particles. For highly energetic relativistic CRs and in order to overcome the time-step restriction, a novel subcycling strategy that retains second-order accuracy in time is presented. Numerical benchmarks and applications including Bell instability, diffusive shock acceleration, and test-particle acceleration in reconnecting layers are discussed.

Analysis of the beam halo in negative ion sources by using 3D3V PIC code

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miyamoto, K., E-mail: kmiyamot@naruto-u.ac.jp; Nishioka, S.; Goto, I.

The physical mechanism of the formation of the negative ion beam halo and the heat loads of the multi-stage acceleration grids are investigated with the 3D PIC (particle in cell) simulation. The following physical mechanism of the beam halo formation is verified: The beam core and the halo consist of the negative ions extracted from the center and the periphery of the meniscus, respectively. This difference of negative ion extraction location results in a geometrical aberration. Furthermore, it is shown that the heat loads on the first acceleration grid and the second acceleration grid are quantitatively improved compared with thosemore » for the 2D PIC simulation result.« less

Modern gyrokinetic particle-in-cell simulation of fusion plasmas on top supercomputers

DOE PAGES

Wang, Bei; Ethier, Stephane; Tang, William; ...

2017-06-29

The Gyrokinetic Toroidal Code at Princeton (GTC-P) is a highly scalable and portable particle-in-cell (PIC) code. It solves the 5D Vlasov-Poisson equation featuring efficient utilization of modern parallel computer architectures at the petascale and beyond. Motivated by the goal of developing a modern code capable of dealing with the physics challenge of increasing problem size with sufficient resolution, new thread-level optimizations have been introduced as well as a key additional domain decomposition. GTC-P's multiple levels of parallelism, including inter-node 2D domain decomposition and particle decomposition, as well as intra-node shared memory partition and vectorization have enabled pushing the scalability ofmore » the PIC method to extreme computational scales. In this paper, we describe the methods developed to build a highly parallelized PIC code across a broad range of supercomputer designs. This particularly includes implementations on heterogeneous systems using NVIDIA GPU accelerators and Intel Xeon Phi (MIC) co-processors and performance comparisons with state-of-the-art homogeneous HPC systems such as Blue Gene/Q. New discovery science capabilities in the magnetic fusion energy application domain are enabled, including investigations of Ion-Temperature-Gradient (ITG) driven turbulence simulations with unprecedented spatial resolution and long temporal duration. Performance studies with realistic fusion experimental parameters are carried out on multiple supercomputing systems spanning a wide range of cache capacities, cache-sharing configurations, memory bandwidth, interconnects and network topologies. These performance comparisons using a realistic discovery-science-capable domain application code provide valuable insights on optimization techniques across one of the broadest sets of current high-end computing platforms worldwide.« less

Modern gyrokinetic particle-in-cell simulation of fusion plasmas on top supercomputers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Bei; Ethier, Stephane; Tang, William

The Gyrokinetic Toroidal Code at Princeton (GTC-P) is a highly scalable and portable particle-in-cell (PIC) code. It solves the 5D Vlasov-Poisson equation featuring efficient utilization of modern parallel computer architectures at the petascale and beyond. Motivated by the goal of developing a modern code capable of dealing with the physics challenge of increasing problem size with sufficient resolution, new thread-level optimizations have been introduced as well as a key additional domain decomposition. GTC-P's multiple levels of parallelism, including inter-node 2D domain decomposition and particle decomposition, as well as intra-node shared memory partition and vectorization have enabled pushing the scalability ofmore » the PIC method to extreme computational scales. In this paper, we describe the methods developed to build a highly parallelized PIC code across a broad range of supercomputer designs. This particularly includes implementations on heterogeneous systems using NVIDIA GPU accelerators and Intel Xeon Phi (MIC) co-processors and performance comparisons with state-of-the-art homogeneous HPC systems such as Blue Gene/Q. New discovery science capabilities in the magnetic fusion energy application domain are enabled, including investigations of Ion-Temperature-Gradient (ITG) driven turbulence simulations with unprecedented spatial resolution and long temporal duration. Performance studies with realistic fusion experimental parameters are carried out on multiple supercomputing systems spanning a wide range of cache capacities, cache-sharing configurations, memory bandwidth, interconnects and network topologies. These performance comparisons using a realistic discovery-science-capable domain application code provide valuable insights on optimization techniques across one of the broadest sets of current high-end computing platforms worldwide.« less

Program Package for 3d PIC Model of Plasma Fiber

NASA Astrophysics Data System (ADS)

Kulhánek, Petr; Břeň, David

2007-08-01

A fully three dimensional Particle in Cell model of the plasma fiber had been developed. The code is written in FORTRAN 95, implementation CVF (Compaq Visual Fortran) under Microsoft Visual Studio user interface. Five particle solvers and two field solvers are included in the model. The solvers have relativistic and non-relativistic variants. The model can deal both with periodical and non-periodical boundary conditions. The mechanism of the surface turbulences generation in the plasma fiber was successfully simulated with the PIC program package.

Resolving the Kinetic Reconnection Length Scale in Global Magnetospheric Simulations with MHD-EPIC

NASA Astrophysics Data System (ADS)

Toth, G.; Chen, Y.; Cassak, P.; Jordanova, V.; Peng, B.; Markidis, S.; Gombosi, T. I.

2016-12-01

We have recently developed a new modeling capability: the Magnetohydrodynamics with Embedded Particle-in-Cell (MHD-EPIC) algorithm with support from Los Alamos SHIELDS and NSF INSPIRE grants. We have implemented MHD-EPIC into the Space Weather Modeling Framework (SWMF) using the implicit Particle-in-Cell (iPIC3D) and the BATS-R-US extended magnetohydrodynamic codes. The MHD-EPIC model allows two-way coupled simulations in two and three dimensions with multiple embedded PIC regions. Both BATS-R-US and iPIC3D are massively parallel codes. The MHD-EPIC approach allows global magnetosphere simulations with embedded kinetic simulations. For small magnetospheres, like Ganymede or Mercury, we can easily resolve the ion scales around the reconnection sites. Modeling the Earth magnetosphere is very challenging even with our efficient MHD-EPIC model due to the large separation between the global and ion scales. On the other hand the large separation of scales may be exploited: the solution may not be sensitive to the ion inertial length as long as it is small relative to the global scales. The ion inertial length can be varied by changing the ion mass while keeping the MHD mass density, the velocity, and pressure the same for the initial and boundary conditions. Our two-dimensional MHD-EPIC simulations for the dayside reconnection region show in fact, that the overall solution is not sensitive to ion inertial length. The shape, size and frequency of flux transfer events are very similar for a wide range of ion masses. Our results mean that 3D MHD-EPIC simulations for the Earth and other large magnetospheres can be made computationally affordable by artificially increasing the ion mass: the required grid resolution and time step in the PIC model are proportional to the ion inertial length. Changing the ion mass by a factor of 4, for example, speeds up the PIC code by a factor of 256. In fact, this approach allowed us to perform an hour-long 3D MHD-EPIC simulations for the Earth magnetosphere.

Photonic Crystal-Based High-Power Backward Wave Oscillator

DOE PAGES

Poole, Brian R.; Harris, John R.

2017-12-01

An electron beam traversing a slow wave structure can be used to either generate or amplify electromagnetic radiation through the interaction of the slow space charge wave on the beam with the slow wave structure modes. Here, a cylindrical waveguide with a periodic array of conducting loops is used for the slow wave structure. This paper considers operation as a backward wave oscillator. The dispersion properties of the structure are determined using a frequency-domain eigenmode solver. The interaction of the electron beam with the structure modes is investigated using a 2-D particle-in-cell (PIC) code. In conclusion, the operating frequency andmore » growth rate dependence on beam energy and beam current are investigated using the PIC code and compared with analytic and scaling estimates where possible.« less

Simulation of multipactor on the rectangular grooved dielectric surface

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cai, Libing; Wang, Jianguo, E-mail: wanguiuc@mail.xjtu.edu.cn; Northwest Institute of Nuclear Technology, Xi'an, Shaanxi 710024

2015-11-15

Multipactor discharge on the rectangular grooved dielectric surface is simulated self-consistently by using a two-and-a-half dimensional (2.5 D) electrostatic particle-in-cell (PIC) code. Compared with the electromagnetic PIC code, the former can give much more accurate solution for the space charge field caused by the multipactor electrons and the deposited surface charge. According to the rectangular groove width and height, the multipactor can be divided into four models, the spatial distributions of the multipactor electrons and the space charge fields are presented for these models. It shows that the rectangular groove in different models gives very different suppression effect on themore » multipactor, effective and efficient suppression on the multipactor can only be reached with a proper groove size.« less

Photonic Crystal-Based High-Power Backward Wave Oscillator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Poole, Brian R.; Harris, John R.

An electron beam traversing a slow wave structure can be used to either generate or amplify electromagnetic radiation through the interaction of the slow space charge wave on the beam with the slow wave structure modes. Here, a cylindrical waveguide with a periodic array of conducting loops is used for the slow wave structure. This paper considers operation as a backward wave oscillator. The dispersion properties of the structure are determined using a frequency-domain eigenmode solver. The interaction of the electron beam with the structure modes is investigated using a 2-D particle-in-cell (PIC) code. In conclusion, the operating frequency andmore » growth rate dependence on beam energy and beam current are investigated using the PIC code and compared with analytic and scaling estimates where possible.« less

Overcoming Challenges in Kinetic Modeling of Magnetized Plasmas and Vacuum Electronic Devices

NASA Astrophysics Data System (ADS)

Omelchenko, Yuri; Na, Dong-Yeop; Teixeira, Fernando

2017-10-01

We transform the state-of-the art of plasma modeling by taking advantage of novel computational techniques for fast and robust integration of multiscale hybrid (full particle ions, fluid electrons, no displacement current) and full-PIC models. These models are implemented in 3D HYPERS and axisymmetric full-PIC CONPIC codes. HYPERS is a massively parallel, asynchronous code. The HYPERS solver does not step fields and particles synchronously in time but instead executes local variable updates (events) at their self-adaptive rates while preserving fundamental conservation laws. The charge-conserving CONPIC code has a matrix-free explicit finite-element (FE) solver based on a sparse-approximate inverse (SPAI) algorithm. This explicit solver approximates the inverse FE system matrix (``mass'' matrix) using successive sparsity pattern orders of the original matrix. It does not reduce the set of Maxwell's equations to a vector-wave (curl-curl) equation of second order but instead utilizes the standard coupled first-order Maxwell's system. We discuss the ability of our codes to accurately and efficiently account for multiscale physical phenomena in 3D magnetized space and laboratory plasmas and axisymmetric vacuum electronic devices.

Cross-verification of the GENE and XGC codes in preparation for their coupling

NASA Astrophysics Data System (ADS)

Jenko, Frank; Merlo, Gabriele; Bhattacharjee, Amitava; Chang, Cs; Dominski, Julien; Ku, Seunghoe; Parker, Scott; Lanti, Emmanuel

2017-10-01

A high-fidelity Whole Device Model (WDM) of a magnetically confined plasma is a crucial tool for planning and optimizing the design of future fusion reactors, including ITER. Aiming at building such a tool, in the framework of the Exascale Computing Project (ECP) the two existing gyrokinetic codes GENE (Eulerian delta-f) and XGC (PIC full-f) will be coupled, thus enabling to carry out first principle kinetic WDM simulations. In preparation for this ultimate goal, a benchmark between the two codes is carried out looking at ITG modes in the adiabatic electron limit. This verification exercise is also joined by the global Lagrangian PIC code ORB5. Linear and nonlinear comparisons have been carried out, neglecting for simplicity collisions and sources. A very good agreement is recovered on frequency, growth rate and mode structure of linear modes. A similarly excellent agreement is also observed comparing the evolution of the heat flux and of the background temperature profile during nonlinear simulations. Work supported by the US DOE under the Exascale Computing Project (17-SC-20-SC).

Simulations of radiation pressure ion acceleration with the VEGA Petawatt laser

NASA Astrophysics Data System (ADS)

Stockhausen, Luca C.; Torres, Ricardo; Conejero Jarque, Enrique

2016-09-01

The Spanish Pulsed Laser Centre (CLPU) is a new high-power laser facility for users. Its main system, VEGA, is a CPA Ti:Sapphire laser which, in its final phase, will be able to reach Petawatt peak powers in pulses of 30 fs with a pulse contrast of 1 :1010 at 1 ps. The extremely low level of pre-pulse intensity makes this system ideally suited for studying the laser interaction with ultrathin targets. We have used the particle-in-cell (PIC) code OSIRIS to carry out 2D simulations of the acceleration of ions from ultrathin solid targets under the unique conditions provided by VEGA, with laser intensities up to 1022 W cm-2 impinging normally on 20 - 60 nm thick overdense plasmas, with different polarizations and pre-plasma scale lengths. We show how signatures of the radiation pressure-dominated regime, such as layer compression and bunch formation, are only present with circular polarization. By passively shaping the density gradient of the plasma, we demonstrate an enhancement in peak energy up to tens of MeV and monoenergetic features. On the contrary linear polarization at the same intensity level causes the target to blow up, resulting in much lower energies and broader spectra. One limiting factor of Radiation Pressure Acceleration is the development of Rayleigh-Taylor like instabilities at the interface of the plasma and photon fluid. This results in the formation of bubbles in the spatial profile of laser-accelerated proton beams. These structures were previously evidenced both experimentally and theoretically. We have performed 2D simulations to characterize this bubble-like structure and report on the dependency on laser and target parameters.

Simulations of ion acceleration from ultrathin targets with the VEGA petawatt laser

NASA Astrophysics Data System (ADS)

Stockhausen, Luca C.; Torres, Ricardo; Conejero Jarque, Enrique

2015-05-01

The Spanish Pulsed Laser Centre (CLPU) is a new high-power laser facility for users. Its main system, VEGA, is a CPA Ti:Sapphire laser which, in its final phase, will be able to reach petawatt peak powers in pulses of 30 fs with a pulse contrast of 1 : 1010 at 1 ps. The extremely low level of pre-pulse intensity makes this system ideally suited for studying the laser interaction with ultrathin targets. We have used the particle-in-cell (PIC) code OSIRIS to carry out 2D simulations of the acceleration of ions from ultrathin solid targets under the unique conditions provided by VEGA, with laser intensities up to 1022Wcm-2 impinging normally on 5 - 40 nm thick overdense plasmas, with different polarizations and pre-plasma scale lengths. We show how signatures of the radiation pressure dominated regime, such as layer compression and bunch formation, are only present with circular polarization. By passively shaping the density gradient of the plasma, we demonstrate an enhancement in peak energy up to tens of MeV and monoenergetic features. On the contrary linear polarization at the same intensity level causes the target to blow up, resulting in much lower energies and broader spectra. One limiting factor of Radiation Pressure Acceleration is the development of Rayleigh-Taylor like instabilities at the interface of the plasma and photon fluid. This results in the formation of bubbles in the spatial profile of laser-accelerated proton beams. These structures were previously evidenced both experimentally and theoretically. We have performed 2D simulations to characterize this bubble-like structure and report on the dependency on laser and target parameters.

Generation of Rising-tone Chorus in a Two-dimensional Mirror Field by Using the General Curvilinear PIC Code

NASA Astrophysics Data System (ADS)

Ke, Y.; Gao, X.; Lu, Q.; Wang, X.; Wang, S.

2017-12-01

Recently, the generation of rising-tone chorus has been implemented with one-dimensional (1-D) particle-in-cell (PIC) simulations in an inhomogeneous background magnetic field, where both the propagation of waves and motion of electrons are simply forced to be parallel to the background magnetic field. We have developed a two-dimensional(2-D) general curvilinear PIC simulation code, and successfully reproduced rising-tone chorus waves excited from an anisotropic electron distribution in a 2-D mirror field. Our simulation results show that whistler waves are mainly generated around the magnetic equator, and continuously gain growth during their propagation toward higher-latitude regions. The rising-tone chorus waves are formed off the magnetic equator, which propagate quasi-parallel to the background magnetic field with the finite wave normal angle. Due to the propagating effect, the wave normal angle of chorus waves is increasing during their propagation toward higher-latitude regions along an enough curved field line. The chirping rate of chorus waves are found to be larger along a field line more close to the middle field line in the mirror field.

Generation of rising-tone chorus in a two-dimensional mirror field by using the general curvilinear PIC code

NASA Astrophysics Data System (ADS)

Ke, Yangguang; Gao, Xinliang; Lu, Quanming; Wang, Xueyi; Wang, Shui

2017-08-01

Recently, the generation of rising-tone chorus has been implemented with one-dimensional (1-D) particle-in-cell (PIC) simulations in an inhomogeneous background magnetic field, where both the propagation of waves and motion of electrons are simply forced to be parallel to the background magnetic field. In this paper, we have developed a two-dimensional (2-D) general curvilinear PIC simulation code and successfully reproduced rising-tone chorus waves excited from an anisotropic electron distribution in a 2-D mirror field. Our simulation results show that whistler waves are mainly generated around the magnetic equator and continuously gain growth during their propagation toward higher-latitude regions. The rising-tone chorus waves are observed off the magnetic equator, which propagate quasi-parallel to the background magnetic field with the wave normal angle smaller than 25°. Due to the propagating effect, the wave normal angle of chorus waves is increasing during their propagation toward higher-latitude regions along an enough curved field line. The chirping rate of chorus waves is found to be larger along a field line with a smaller curvature.

High fidelity 3-dimensional models of beam-electron cloud interactions in circular accelerators

NASA Astrophysics Data System (ADS)

Feiz Zarrin Ghalam, Ali

Electron cloud is a low-density electron profile created inside the vacuum chamber of circular machines with positively charged beams. Electron cloud limits the peak current of the beam and degrades the beams' quality through luminosity degradation, emittance growth and head to tail or bunch to bunch instability. The adverse effects of electron cloud on long-term beam dynamics becomes more and more important as the beams go to higher and higher energies. This problem has become a major concern in many future circular machines design like the Large Hadron Collider (LHC) under construction at European Center for Nuclear Research (CERN). Due to the importance of the problem several simulation models have been developed to model long-term beam-electron cloud interaction. These models are based on "single kick approximation" where the electron cloud is assumed to be concentrated at one thin slab around the ring. While this model is efficient in terms of computational costs, it does not reflect the real physical situation as the forces from electron cloud to the beam are non-linear contrary to this model's assumption. To address the existing codes limitation, in this thesis a new model is developed to continuously model the beam-electron cloud interaction. The code is derived from a 3-D parallel Particle-In-Cell (PIC) model (QuickPIC) originally used for plasma wakefield acceleration research. To make the original model fit into circular machines environment, betatron and synchrotron equations of motions have been added to the code, also the effect of chromaticity, lattice structure have been included. QuickPIC is then benchmarked against one of the codes developed based on single kick approximation (HEAD-TAIL) for the transverse spot size of the beam in CERN-LHC. The growth predicted by QuickPIC is less than the one predicted by HEAD-TAIL. The code is then used to investigate the effect of electron cloud image charges on the long-term beam dynamics, particularly on the transverse tune shift of the beam at CERN Super Proton Synchrotron (SPS) ring. The force from the electron cloud image charges on the beam cancels the force due to cloud compression formed on the beam axis and therefore the tune shift is mainly due to the uniform electron cloud density. (Abstract shortened by UMI.)

On-Site Inspection RadioIsotopic Spectroscopy (Osiris) System Development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Caffrey, Gus J.; Egger, Ann E.; Krebs, Kenneth M.

2015-09-01

We have designed and tested hardware and software for the acquisition and analysis of high-resolution gamma-ray spectra during on-site inspections under the Comprehensive Nuclear-Test-Ban Treaty (CTBT). The On-Site Inspection RadioIsotopic Spectroscopy—Osiris—software filters the spectral data to display only radioisotopic information relevant to CTBT on-site inspections, e.g.,132I. A set of over 100 fission-product spectra was employed for Osiris testing. These spectra were measured, where possible, or generated by modeling. The synthetic test spectral compositions include non-nuclear-explosion scenarios, e.g., a severe nuclear reactor accident, and nuclear-explosion scenarios such as a vented underground nuclear test. Comparing its computer-based analyses to expert visual analysesmore » of the test spectra, Osiris correctly identifies CTBT-relevant fission product isotopes at the 95% level or better.The Osiris gamma-ray spectrometer is a mechanically-cooled, battery-powered ORTEC Transpec-100, chosen to avoid the need for liquid nitrogen during on-site inspections. The spectrometer was used successfully during the recent 2014 CTBT Integrated Field Exercise in Jordan. The spectrometer is controlled and the spectral data analyzed by a Panasonic Toughbook notebook computer. To date, software development has been the main focus of the Osiris project. In FY2016-17, we plan to modify the Osiris hardware, integrate the Osiris software and hardware, and conduct rigorous field tests to ensure that the Osiris system will function correctly during CTBT on-site inspections. The planned development will raise Osiris to technology readiness level TRL-8; transfer the Osiris technology to a commercial manufacturer, and demonstrate Osiris to potential CTBT on-site inspectors.« less

Simulation of stimulated Brillouin scattering and stimulated Raman scattering in shock ignition

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hao, L.; Li, J.; Liu, W. D.

2016-04-15

We study stimulated Brillouin scattering (SBS) and stimulated Raman scattering (SRS) in shock ignition by comparing fluid and particle-in-cell (PIC) simulations. Under typical parameters for the OMEGA experiments [Theobald et al., Phys. Plasmas 19, 102706 (2012)], a series of 1D fluid simulations with laser intensities ranging between 2 × 10{sup 15} and 2 × 10{sup 16 }W/cm{sup 2} finds that SBS is the dominant instability, which increases significantly with the incident intensity. Strong pump depletion caused by SBS and SRS limits the transmitted intensity at the 0.17n{sub c} to be less than 3.5 × 10{sup 15 }W/cm{sup 2}. The PIC simulations show similar physics but with higher saturationmore » levels for SBS and SRS convective modes and stronger pump depletion due to higher seed levels for the electromagnetic fields in PIC codes. Plasma flow profiles are found to be important in proper modeling of SBS and limiting its reflectivity in both the fluid and PIC simulations.« less

Design and simulation of a gyroklystron amplifier

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chauhan, M. S., E-mail: mschauhan.rs.ece@iitbhu.ac.in; Swati, M. V.; Jain, P. K.

2015-03-15

In the present paper, a design methodology of the gyroklystron amplifier has been described and subsequently used for the design of a typically selected 200 kW, Ka-band, four-cavity gyroklystron amplifier. This conceptual device design has been validated through the 3D particle-in-cell (PIC) simulation and nonlinear analysis. Commercially available PIC simulation code “MAGIC” has been used for the electromagnetic study at the different location of the device RF interaction structure for the beam-absent case, i.e., eigenmode study as well as for the electron beam and RF wave interaction behaviour study in the beam present case of the gyroklystron. In addition, a practicalmore » problem of misalignment of the RF cavities with drift tubes within the tube has been also investigated and its effect on device performance studied. The analytical and simulation results confirmed the validity of the gyroklystron device design. The PIC simulation results of the present gyroklystron produced a stable RF output power of ∼218 kW for 0% velocity spread at 35 GHz, with ∼45 dB gain, 37% efficiency, and a bandwidth of 0.3% for a 70 kV, 8.2 A gyrating electron beam. The simulated values of RF output power have been found in agreement with the nonlinear analysis results within ∼5%. Further, the PIC simulation has been extended to study a practical problem of misalignment of the cavities axis and drift tube axis of the gyroklystron amplifier and found that the RF output power is more sensitive to misalignments in comparison to the device bandwidth. The present paper, gyroklystron device design, nonlinear analysis, and 3D PIC simulation using commercially available code had been systematically described would be of use to the high-power gyro-amplifier tube designers and research scientists.« less

The OTELO Project

NASA Astrophysics Data System (ADS)

Cepa, J.; Alfaro, E. J.; Castañeda, H. O.; Gallego, J.; González-Serrano, J. I.; González, J. J.; Jones, D. H.; Pérez-García, A. M.; Sánchez-Portal, M.

2007-06-01

OSIRIS is the Spanish Day One instrument for the GTC 10.4-m telescope. OSIRIS is a general purpose instrument for imaging, low-resolution long slit and multi-object spectroscopy (MOS). OSIRIS has a field of view of 8.6×8.6 arcminutes, which makes it ideal for deep surveys, and operates in the optical wavelength range from 365 through 1000nm. The main characteristic that makes OSIRIS unique amongst other instruments in 8-10m class telescopes is the use of Tunable Filters (Bland-Hawthorn & Jones 1998). These allow a continuous selection of both the central wavelength and the width, thus providing scanning narrow band imaging within the OSIRIS wavelength range. The combination of the large GTC aperture, large OSIRIS field of view and availability of the TFs makes OTELO a truly unique emission line survey.

Dissemination and support of ARGUS for accelerator applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The ARGUS code is a three-dimensional code system for simulating for interactions between charged particles, electric and magnetic fields, and complex structure. It is a system of modules that share common utilities for grid and structure input, data handling, memory management, diagnostics, and other specialized functions. The code includes the fields due to the space charge and current density of the particles to achieve a self-consistent treatment of the particle dynamics. The physic modules in ARGUS include three-dimensional field solvers for electrostatics and electromagnetics, a three-dimensional electromagnetic frequency-domain module, a full particle-in-cell (PIC) simulation module, and a steady-state PIC model.more » These are described in the Appendix to this report. This project has a primary mission of developing the capabilities of ARGUS in accelerator modeling of release to the accelerator design community. Five major activities are being pursued in parallel during the first year of the project. To improve the code and/or add new modules that provide capabilities needed for accelerator design. To produce a User's Guide that documents the use of the code for all users. To release the code and the User's Guide to accelerator laboratories for their own use, and to obtain feed-back from the. To build an interactive user interface for setting up ARGUS calculations. To explore the use of ARGUS on high-power workstation platforms.« less

NASA's OSIRIS-REx Spacecraft In Thermal Vacuum Testing

NASA Image and Video Library

2017-12-08

The OSIRIS-REx spacecraft being lifted into the thermal vacuum chamber at Lockheed Martin for environmental testing. Credits: Lockheed Martin Read more: www.nasa.gov/feature/goddard/2016/osiris-rex-in-thermal-vac

Pacific Northwest National Laboratory Potential Impact Categories for Radiological Air Emission Monitoring

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ballinger, Marcel Y.; Gervais, Todd L.; Barnett, J. Matthew

2012-06-05

In 2002, the EPA amended 40 CFR 61 Subpart H and 40 CFR 61 Appendix B Method 114 to include requirements from ANSI/HPS N13.1-1999 Sampling and Monitoring Releases of Airborne Radioactive Substances from the Stack and Ducts of Nuclear Facilities for major emission points. Additionally, the WDOH amended the Washington Administrative Code (WAC) 246-247 Radiation protection-air emissions to include ANSI/HPS N13.1-1999 requirements for major and minor emission points when new permitting actions are approved. A result of the amended regulations is the requirement to prepare a written technical basis for the radiological air emission sampling and monitoring program. A keymore » component of the technical basis is the Potential Impact Category (PIC) assigned to an emission point. This paper discusses the PIC assignments for the Pacific Northwest National Laboratory (PNNL) Integrated Laboratory emission units; this revision includes five PIC categories.« less

Anomalous photo-ionization of 4d shell in medium-Z ionized atoms

NASA Astrophysics Data System (ADS)

Klapisch, M.; Busquet, M.

2013-09-01

Photoionization (PI) cross sections (PICS) are necessary for the simulation of astrophysical and ICF plasmas. In order to be used in plasma modeling, the PICS are usually fit to simple analytical formulas. We observed an unusual spectral shape of the PICS of the 4d shell of ionized Xe and other elements, computed with different codes: a local minimum occurs around twice the threshold energy. We explain this phenomenon as interference between the bound 4d wavefunction and the free electron wavefunction, which is similar to the Cooper minima for neutral atoms. Consequently, the usual fitting formulas, which consist of a combination of inverse powers of the frequency beyond threshold, may yield rates for PI and radiative recombination (RR) that are incorrect by orders of magnitude. A new fitting algorithm is proposed and is included in the latest version of HULLAC.v9.5.

Hybrid 3D model for the interaction of plasma thruster plumes with nearby objects

NASA Astrophysics Data System (ADS)

Cichocki, Filippo; Domínguez-Vázquez, Adrián; Merino, Mario; Ahedo, Eduardo

2017-12-01

This paper presents a hybrid particle-in-cell (PIC) fluid approach to model the interaction of a plasma plume with a spacecraft and/or any nearby object. Ions and neutrals are modeled with a PIC approach, while electrons are treated as a fluid. After a first iteration of the code, the domain is split into quasineutral and non-neutral regions, based on non-neutrality criteria, such as the relative charge density and the Debye length-to-cell size ratio. At the material boundaries of the former quasineutral region, a dedicated algorithm ensures that the Bohm condition is met. In the latter non-neutral regions, the electron density and electric potential are obtained by solving the coupled electron momentum balance and Poisson equations. Boundary conditions for both the electric current and potential are finally obtained with a plasma sheath sub-code and an equivalent circuit model. The hybrid code is validated by applying it to a typical plasma plume-spacecraft interaction scenario, and the physics and capabilities of the model are finally discussed.

Exploiting multi-scale parallelism for large scale numerical modelling of laser wakefield accelerators

NASA Astrophysics Data System (ADS)

Fonseca, R. A.; Vieira, J.; Fiuza, F.; Davidson, A.; Tsung, F. S.; Mori, W. B.; Silva, L. O.

2013-12-01

A new generation of laser wakefield accelerators (LWFA), supported by the extreme accelerating fields generated in the interaction of PW-Class lasers and underdense targets, promises the production of high quality electron beams in short distances for multiple applications. Achieving this goal will rely heavily on numerical modelling to further understand the underlying physics and identify optimal regimes, but large scale modelling of these scenarios is computationally heavy and requires the efficient use of state-of-the-art petascale supercomputing systems. We discuss the main difficulties involved in running these simulations and the new developments implemented in the OSIRIS framework to address these issues, ranging from multi-dimensional dynamic load balancing and hybrid distributed/shared memory parallelism to the vectorization of the PIC algorithm. We present the results of the OASCR Joule Metric program on the issue of large scale modelling of LWFA, demonstrating speedups of over 1 order of magnitude on the same hardware. Finally, scalability to over ˜106 cores and sustained performance over ˜2 P Flops is demonstrated, opening the way for large scale modelling of LWFA scenarios.

CPIC: a curvilinear Particle-In-Cell code for plasma-material interaction studies

NASA Astrophysics Data System (ADS)

Delzanno, G.; Camporeale, E.; Moulton, J. D.; Borovsky, J. E.; MacDonald, E.; Thomsen, M. F.

2012-12-01

We present a recently developed Particle-In-Cell (PIC) code in curvilinear geometry called CPIC (Curvilinear PIC) [1], where the standard PIC algorithm is coupled with a grid generation/adaptation strategy. Through the grid generator, which maps the physical domain to a logical domain where the grid is uniform and Cartesian, the code can simulate domains of arbitrary complexity, including the interaction of complex objects with a plasma. At present the code is electrostatic. Poisson's equation (in logical space) can be solved with either an iterative method based on the Conjugate Gradient (CG) or the Generalized Minimal Residual (GMRES) coupled with a multigrid solver used as a preconditioner, or directly with multigrid. The multigrid strategy is critical for the solver to perform optimally or nearly optimally as the dimension of the problem increases. CPIC also features a hybrid particle mover, where the computational particles are characterized by position in logical space and velocity in physical space. The advantage of a hybrid mover, as opposed to more conventional movers that move particles directly in the physical space, is that the interpolation of the particles in logical space is straightforward and computationally inexpensive, since one does not have to track the position of the particle. We will present our latest progress on the development of the code and document the code performance on standard plasma-physics tests. Then we will present the (preliminary) application of the code to a basic dynamic-charging problem, namely the charging and shielding of a spherical spacecraft in a magnetized plasma for various level of magnetization and including the pulsed emission of an electron beam from the spacecraft. The dynamical evolution of the sheath and the time-dependent current collection will be described. This study is in support of the ConnEx mission concept to use an electron beam from a magnetospheric spacecraft to trace magnetic field lines from the magnetosphere to the ionosphere [2]. [1] G.L. Delzanno, E. Camporeale, "CPIC: a new Particle-in-Cell code for plasma-material interaction studies", in preparation (2012). [2] J.E. Borovsky, D.J. McComas, M.F. Thomsen, J.L. Burch, J. Cravens, C.J. Pollock, T.E. Moore, and S.B. Mende, "Magnetosphere-Ionosphere Observatory (MIO): A multisatellite mission designed to solve the problem of what generates auroral arcs," Eos. Trans. Amer. Geophys. Union 79 (45), F744 (2000).

Self-modulated laser wakefield accelerators as x-ray sources

DOE PAGES

Lemos, N.; Martins, J. L.; Tsung, F. S.; ...

2016-02-17

The development of a directional, small-divergence, and short-duration picosecond x-ray probe beam with an energy greater than 50 keV is desirable for high energy density science experiments. We therefore explore through particle-in-cell (PIC) computer simulations the possibility of using x-rays radiated by betatron-like motion of electrons from a self-modulated laser wakefield accelerator as a possible candidate to meet this need. Two OSIRIS 2D PIC simulations with mobile ions are presented, one with a normalized vector potential a 0 = 1.5 and the other with an a 0 = 3. We find that in both cases direct laser acceleration (DLA) ismore » an important additional acceleration mechanism in addition to the longitudinal electric field of the plasma wave. Together these mechanisms produce electrons with a continuous energy spectrum with a maximum energy of 300 MeV for a 0 = 3 case and 180 MeV in the a 0 = 1.5 case. Forward-directed x-ray radiation with a photon energy up to 100 keV was calculated for the a 0 = 3 case and up to 12 keV for the a 0 = 1.5 case. The x-ray spectrum can be fitted with a sum of two synchrotron spectra with critical photon energies of 13 and 45 keV for the a 0 of 3 and critical photon energies of 0.3 and 1.4 keV for a 0 of 1.5 in the plane of polarization of the laser. As a result, the full width at half maximum divergence angle of the x-rays was 62 × 1.9 mrad for a 0 = 3 and 77 × 3.8 mrad for a 0 = 1.5.« less

PerSEUS: Ultra-Low-Power High Performance Computing for Plasma Simulations

NASA Astrophysics Data System (ADS)

Doxas, I.; Andreou, A.; Lyon, J.; Angelopoulos, V.; Lu, S.; Pritchett, P. L.

2017-12-01

Peta-op SupErcomputing Unconventional System (PerSEUS) aims to explore the use for High Performance Scientific Computing (HPC) of ultra-low-power mixed signal unconventional computational elements developed by Johns Hopkins University (JHU), and demonstrate that capability on both fluid and particle Plasma codes. We will describe the JHU Mixed-signal Unconventional Supercomputing Elements (MUSE), and report initial results for the Lyon-Fedder-Mobarry (LFM) global magnetospheric MHD code, and a UCLA general purpose relativistic Particle-In-Cell (PIC) code.

Pedestrian injury causation study (pedestrian accident typing)

DOT National Transportation Integrated Search

1982-08-01

A new computerized pedestrian accident typing procedure was tested on 1,997 cases from the Pedestrian Injury Causation Study (PICS). Two coding procedures were used to determine the effects of quantity and quality of information on accident typing ac...

OSIRIS-REx Prelaunch News Conference

NASA Image and Video Library

2016-09-06

In the Kennedy Space Center’s Press Site auditorium, Scott Messer, program manager for NASA missions at United Launch Alliance in Centennial, Colorado; Michael Donnelly, OSIRIS-REx project manager at NASA’s Goddard Space Flight Center in Greenbelt, Maryland; and Rich Kuhns, OSIRIS-REx program manager for Lockheed Martin Space Systems in Denver; speak to members of the media at a prelaunch news conference for the agency’s Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer, or OSIRIS-REx spacecraft.

Genetic and molecular characterization of the maize rp3 rust resistance locus.

PubMed Central

Webb, Craig A; Richter, Todd E; Collins, Nicholas C; Nicolas, Marie; Trick, Harold N; Pryor, Tony; Hulbert, Scot H

2002-01-01

In maize, the Rp3 gene confers resistance to common rust caused by Puccinia sorghi. Flanking marker analysis of rust-susceptible rp3 variants suggested that most of them arose via unequal crossing over, indicating that rp3 is a complex locus like rp1. The PIC13 probe identifies a nucleotide binding site-leucine-rich repeat (NBS-LRR) gene family that maps to the complex. Rp3 variants show losses of PIC13 family members relative to the resistant parents when probed with PIC13, indicating that the Rp3 gene is a member of this family. Gel blots and sequence analysis suggest that at least 9 family members are at the locus in most Rp3-carrying lines and that at least 5 of these are transcribed in the Rp3-A haplotype. The coding regions of 14 family members, isolated from three different Rp3-carrying haplotypes, had DNA sequence identities from 93 to 99%. Partial sequencing of clones of a BAC contig spanning the rp3 locus in the maize inbred line B73 identified five different PIC13 paralogues in a region of approximately 140 kb. PMID:12242248

Dissemination and support of ARGUS for accelerator applications. Technical progress report, April 24, 1991--January 20, 1992

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The ARGUS code is a three-dimensional code system for simulating for interactions between charged particles, electric and magnetic fields, and complex structure. It is a system of modules that share common utilities for grid and structure input, data handling, memory management, diagnostics, and other specialized functions. The code includes the fields due to the space charge and current density of the particles to achieve a self-consistent treatment of the particle dynamics. The physic modules in ARGUS include three-dimensional field solvers for electrostatics and electromagnetics, a three-dimensional electromagnetic frequency-domain module, a full particle-in-cell (PIC) simulation module, and a steady-state PIC model.more » These are described in the Appendix to this report. This project has a primary mission of developing the capabilities of ARGUS in accelerator modeling of release to the accelerator design community. Five major activities are being pursued in parallel during the first year of the project. To improve the code and/or add new modules that provide capabilities needed for accelerator design. To produce a User`s Guide that documents the use of the code for all users. To release the code and the User`s Guide to accelerator laboratories for their own use, and to obtain feed-back from the. To build an interactive user interface for setting up ARGUS calculations. To explore the use of ARGUS on high-power workstation platforms.« less

Towards robust algorithms for current deposition and dynamic load-balancing in a GPU particle in cell code

NASA Astrophysics Data System (ADS)

Rossi, Francesco; Londrillo, Pasquale; Sgattoni, Andrea; Sinigardi, Stefano; Turchetti, Giorgio

2012-12-01

We present `jasmine', an implementation of a fully relativistic, 3D, electromagnetic Particle-In-Cell (PIC) code, capable of running simulations in various laser plasma acceleration regimes on Graphics-Processing-Units (GPUs) HPC clusters. Standard energy/charge preserving FDTD-based algorithms have been implemented using double precision and quadratic (or arbitrary sized) shape functions for the particle weighting. When porting a PIC scheme to the GPU architecture (or, in general, a shared memory environment), the particle-to-grid operations (e.g. the evaluation of the current density) require special care to avoid memory inconsistencies and conflicts. Here we present a robust implementation of this operation that is efficient for any number of particles per cell and particle shape function order. Our algorithm exploits the exposed GPU memory hierarchy and avoids the use of atomic operations, which can hurt performance especially when many particles lay on the same cell. We show the code multi-GPU scalability results and present a dynamic load-balancing algorithm. The code is written using a python-based C++ meta-programming technique which translates in a high level of modularity and allows for easy performance tuning and simple extension of the core algorithms to various simulation schemes.

Status report on the 'Merging' of the Electron-Cloud Code POSINST with the 3-D Accelerator PIC CODE WARP

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vay, J.-L.; Furman, M.A.; Azevedo, A.W.

2004-04-19

We have integrated the electron-cloud code POSINST [1] with WARP [2]--a 3-D parallel Particle-In-Cell accelerator code developed for Heavy Ion Inertial Fusion--so that the two can interoperate. Both codes are run in the same process, communicate through a Python interpreter (already used in WARP), and share certain key arrays (so far, particle positions and velocities). Currently, POSINST provides primary and secondary sources of electrons, beam bunch kicks, a particle mover, and diagnostics. WARP provides the field solvers and diagnostics. Secondary emission routines are provided by the Tech-X package CMEE.

The OVIRS Visible/IR Spectrometer on the OSIRIS-Rex Mission

NASA Technical Reports Server (NTRS)

Reuter, D. C.; Simon-Miller, A. A.

2012-01-01

The OSIRIS-REx (Origins Spectral Interpretation Resource Identification Security Regolith Explorer) Mission is a planetary science mission to study, and return a sample from, the carbonaceous asteroid 1999 RQ-36. The third mission selected under NASA's New Frontiers Program, it is scheduled to be launched in 2016. It is led by PI Dante Lauretta at the University of Arizona and managed by NASA's Goddard Space Flight Center. The spacecraft and the asteroid sampling mechanism, TAGSAM (Touch-And-Go Sample Acquisition Mechanism) will be provided by Lockheed Martin Space Systems. Instrumentation for studying the asteroid include: OCAMS (the OSIRIS-REx Camera Suite), OLA (the OSIRIS-REx Laser Altimeter, a scanning LIDAR), OTES (The OSIRIS-REx Thermal Emission Spectrometer, a 4-50 micron point spectrometer) and OVIRS (the OSIRIS-REx Visible and IR Spectrometer, a 0.4 to 4.3 micron point spectrometer). The payload also includes REXIS (the Regolith X-ray Imaging Spectrometer) a student provided experiment. This paper presents a description of the OVIRS instrument.

The OSIRIS-REx Laser Altimeter (OLA) Investigation and Instrument

NASA Astrophysics Data System (ADS)

Daly, M. G.; Barnouin, O. S.; Dickinson, C.; Seabrook, J.; Johnson, C. L.; Cunningham, G.; Haltigin, T.; Gaudreau, D.; Brunet, C.; Aslam, I.; Taylor, A.; Bierhaus, E. B.; Boynton, W.; Nolan, M.; Lauretta, D. S.

2017-10-01

The Canadian Space Agency (CSA) has contributed to the Origins Spectral Interpretation Resource Identification Security-Regolith Explorer (OSIRIS-REx) spacecraft the OSIRIS-REx Laser Altimeter (OLA). The OSIRIS-REx mission will sample asteroid 101955 Bennu, the first B-type asteroid to be visited by a spacecraft. Bennu is thought to be primitive, carbonaceous, and spectrally most closely related to CI and/or CM meteorites. As a scanning laser altimeter, the OLA instrument will measure the range between the OSIRIS-REx spacecraft and the surface of Bennu to produce digital terrain maps of unprecedented spatial scales for a planetary mission. The digital terrain maps produced will measure ˜7 cm per pixel globally, and ˜3 cm per pixel at specific sample sites. In addition, OLA data will be used to constrain and refine the spacecraft trajectories. Global maps and highly accurate spacecraft trajectory estimates are critical to infer the internal structure of the asteroid. The global and regional maps also are key to gain new insights into the surface processes acting across Bennu, which inform the selection of the OSIRIS-REx sample site. These, in turn, are essential for understanding the provenance of the regolith sample collected by the OSIRIS-REx spacecraft. The OLA data also are important for quantifying any hazards near the selected OSIRIS-REx sample site and for evaluating the range of tilts at the sampling site for comparison against the capabilities of the sample acquisition device.

On the numerical dispersion of electromagnetic particle-in-cell code: Finite grid instability

NASA Astrophysics Data System (ADS)

Meyers, M. D.; Huang, C.-K.; Zeng, Y.; Yi, S. A.; Albright, B. J.

2015-09-01

The Particle-In-Cell (PIC) method is widely used in relativistic particle beam and laser plasma modeling. However, the PIC method exhibits numerical instabilities that can render unphysical simulation results or even destroy the simulation. For electromagnetic relativistic beam and plasma modeling, the most relevant numerical instabilities are the finite grid instability and the numerical Cherenkov instability. We review the numerical dispersion relation of the Electromagnetic PIC model. We rigorously derive the faithful 3-D numerical dispersion relation of the PIC model, for a simple, direct current deposition scheme, which does not conserve electric charge exactly. We then specialize to the Yee FDTD scheme. In particular, we clarify the presence of alias modes in an eigenmode analysis of the PIC model, which combines both discrete and continuous variables. The manner in which the PIC model updates and samples the fields and distribution function, together with the temporal and spatial phase factors from solving Maxwell's equations on the Yee grid with the leapfrog scheme, is explicitly accounted for. Numerical solutions to the electrostatic-like modes in the 1-D dispersion relation for a cold drifting plasma are obtained for parameters of interest. In the succeeding analysis, we investigate how the finite grid instability arises from the interaction of the numerical modes admitted in the system and their aliases. The most significant interaction is due critically to the correct representation of the operators in the dispersion relation. We obtain a simple analytic expression for the peak growth rate due to this interaction, which is then verified by simulation. We demonstrate that our analysis is readily extendable to charge conserving models.

On the numerical dispersion of electromagnetic particle-in-cell code: Finite grid instability

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meyers, M.D., E-mail: mdmeyers@physics.ucla.edu; Department of Physics and Astronomy, University of California Los Angeles, Los Angeles, CA 90095; Huang, C.-K., E-mail: huangck@lanl.gov

The Particle-In-Cell (PIC) method is widely used in relativistic particle beam and laser plasma modeling. However, the PIC method exhibits numerical instabilities that can render unphysical simulation results or even destroy the simulation. For electromagnetic relativistic beam and plasma modeling, the most relevant numerical instabilities are the finite grid instability and the numerical Cherenkov instability. We review the numerical dispersion relation of the Electromagnetic PIC model. We rigorously derive the faithful 3-D numerical dispersion relation of the PIC model, for a simple, direct current deposition scheme, which does not conserve electric charge exactly. We then specialize to the Yee FDTDmore » scheme. In particular, we clarify the presence of alias modes in an eigenmode analysis of the PIC model, which combines both discrete and continuous variables. The manner in which the PIC model updates and samples the fields and distribution function, together with the temporal and spatial phase factors from solving Maxwell's equations on the Yee grid with the leapfrog scheme, is explicitly accounted for. Numerical solutions to the electrostatic-like modes in the 1-D dispersion relation for a cold drifting plasma are obtained for parameters of interest. In the succeeding analysis, we investigate how the finite grid instability arises from the interaction of the numerical modes admitted in the system and their aliases. The most significant interaction is due critically to the correct representation of the operators in the dispersion relation. We obtain a simple analytic expression for the peak growth rate due to this interaction, which is then verified by simulation. We demonstrate that our analysis is readily extendable to charge conserving models.« less

An efficient and portable SIMD algorithm for charge/current deposition in Particle-In-Cell codes

NASA Astrophysics Data System (ADS)

Vincenti, H.; Lobet, M.; Lehe, R.; Sasanka, R.; Vay, J.-L.

2017-01-01

In current computer architectures, data movement (from die to network) is by far the most energy consuming part of an algorithm (≈ 20 pJ/word on-die to ≈10,000 pJ/word on the network). To increase memory locality at the hardware level and reduce energy consumption related to data movement, future exascale computers tend to use many-core processors on each compute nodes that will have a reduced clock speed to allow for efficient cooling. To compensate for frequency decrease, machine vendors are making use of long SIMD instruction registers that are able to process multiple data with one arithmetic operator in one clock cycle. SIMD register length is expected to double every four years. As a consequence, Particle-In-Cell (PIC) codes will have to achieve good vectorization to fully take advantage of these upcoming architectures. In this paper, we present a new algorithm that allows for efficient and portable SIMD vectorization of current/charge deposition routines that are, along with the field gathering routines, among the most time consuming parts of the PIC algorithm. Our new algorithm uses a particular data structure that takes into account memory alignment constraints and avoids gather/scatter instructions that can significantly affect vectorization performances on current CPUs. The new algorithm was successfully implemented in the 3D skeleton PIC code PICSAR and tested on Haswell Xeon processors (AVX2-256 bits wide data registers). Results show a factor of × 2 to × 2.5 speed-up in double precision for particle shape factor of orders 1- 3. The new algorithm can be applied as is on future KNL (Knights Landing) architectures that will include AVX-512 instruction sets with 512 bits register lengths (8 doubles/16 singles).

OSIRIS-REx NASA Social

NASA Image and Video Library

2016-09-07

Social media followers were briefed by NASA scientists on asteroids, how they relate to the origins of our solar system and the search for life beyond Earth, during a NASA Social presentation in the Operations Support Building II at the agency’s Kennedy Space Center in Florida. The presentation took place before launch of the agency’s Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer, or OSIRIS-REx spacecraft. From the left, are Dante Lauretta, OSIRIS-REx principal investigator from the University of Arizona at Tucson, and Christina Richey, OSIRIS-REx deputy program scientists at NASA Headquarters in Washington.

Global linear gyrokinetic simulations for LHD including collisions

NASA Astrophysics Data System (ADS)

Kauffmann, K.; Kleiber, R.; Hatzky, R.; Borchardt, M.

2010-11-01

The code EUTERPE uses a Particle-In-Cell (PIC) method to solve the gyrokinetic equation globally (full radius, full flux surface) for three-dimensional equilibria calculated with VMEC. Recently this code has been extended to include multiple kinetic species and electromagnetic effects. Additionally, a pitch-angle scattering operator has been implemented in order to include collisional effects in the simulation of instabilities and to be able to simulate neoclassical transport. As a first application of this extended code we study the effects of collisions on electrostatic ion-temperature-gradient (ITG) instabilities in LHD.

Simulations of the plasma dynamics in high-current ion diodes

NASA Astrophysics Data System (ADS)

Boine-Frankenheim, O.; Pointon, T. D.; Mehlhorn, T. A.

Our time-implicit fluid/Particle-In-Cell (PIC) code DYNAID [1]is applied to problems relevant for applied- B ion diode operation. We present simulations of the laser ion source, which will soon be employed on the SABRE accelerator at SNL, and of the dynamics of the anode source plasma in the applied electric and magnetic fields. DYNAID is still a test-bed for a higher-dimensional simulation code. Nevertheless, the code can already give new theoretical insight into the dynamics of plasmas in pulsed power devices.

Hybrid-PIC Computer Simulation of the Plasma and Erosion Processes in Hall Thrusters

NASA Technical Reports Server (NTRS)

Hofer, Richard R.; Katz, Ira; Mikellides, Ioannis G.; Gamero-Castano, Manuel

2010-01-01

HPHall software simulates and tracks the time-dependent evolution of the plasma and erosion processes in the discharge chamber and near-field plume of Hall thrusters. HPHall is an axisymmetric solver that employs a hybrid fluid/particle-in-cell (Hybrid-PIC) numerical approach. HPHall, originally developed by MIT in 1998, was upgraded to HPHall-2 by the Polytechnic University of Madrid in 2006. The Jet Propulsion Laboratory has continued the development of HPHall-2 through upgrades to the physical models employed in the code, and the addition of entirely new ones. Primary among these are the inclusion of a three-region electron mobility model that more accurately depicts the cross-field electron transport, and the development of an erosion sub-model that allows for the tracking of the erosion of the discharge chamber wall. The code is being developed to provide NASA science missions with a predictive tool of Hall thruster performance and lifetime that can be used to validate Hall thrusters for missions.

First PIC simulations modeling the interaction of ultra-intense lasers with sub-micron, liquid crystal targets

NASA Astrophysics Data System (ADS)

McMahon, Matthew; Poole, Patrick; Willis, Christopher; Andereck, David; Schumacher, Douglass

2014-10-01

We recently introduced liquid crystal films as on-demand, variable thickness (50-5000 nanometers), low cost targets for intense laser experiments. Here we present the first particle-in-cell (PIC) simulations of short pulse laser excitation of liquid crystal targets treating Scarlet (OSU) class lasers using the PIC code LSP. In order to accurately model the target evolution, a low starting temperature and field ionization model are employed. This is essential as large starting temperatures, often used to achieve large Debye lengths, lead to expansion of the target causing significant reduction of the target density before the laser pulse can interact. We also present an investigation of the modification of laser pulses by very thin targets. This work was supported by the DARPA PULSE program through a grant from ARMDEC, by the US Department of Energy under Contract No. DE-NA0001976, and allocations of computing time from the Ohio Supercomputing Center.

Plasmoid statistics in relativistic magnetic reconnection

NASA Astrophysics Data System (ADS)

Petropoulou, M.; Christie, I. M.; Sironi, L.; Giannios, D.

2018-04-01

Plasmoids, overdense blobs of plasma containing magnetic fields and high-energy particles, are a self-consistent outcome of the reconnection process in the relativistic regime. Recent two-dimensional particle-in-cell (PIC) simulations have shown that plasmoids can undergo a variety of processes (e.g. mergers, bulk acceleration, growth, and advection) within the reconnection layer. We developed a Monte Carlo code, benchmarked with the recent PIC simulations, to examine the effects of these processes on the steady-state size and momentum distributions of the plasmoid chain. The differential plasmoid size distribution is shown to be a power law, ranging from a few plasma skin depths to ˜0.1 of the reconnection layer's length. The power-law slope is shown to be linearly dependent upon the ratio of the plasmoid acceleration and growth rates, which slightly decreases with increasing plasma magnetization. We perform a detailed comparison of our results with those of recent PIC simulations and briefly discuss the astrophysical implications of our findings through the representative case of flaring events from blazar jets.

OSIRIS-REx A NASA Mission to a Near Earth Asteroid!...and Other Recent Happenings in the Solar System

NASA Technical Reports Server (NTRS)

Moreau, Michael C.

2015-01-01

The OSIRIS-REx Mission launches in 2016 Arrives at Asteroid Bennu-2018 Returns a sample to Earth -2023 The mission, OSIRIS-REx, will visit an asteroid and return a sample from the early Solar System to help us understand how our Solar System formed.

Low-temperature plasma simulations with the LSP PIC code

NASA Astrophysics Data System (ADS)

Carlsson, Johan; Khrabrov, Alex; Kaganovich, Igor; Keating, David; Selezneva, Svetlana; Sommerer, Timothy

2014-10-01

The LSP (Large-Scale Plasma) PIC-MCC code has been used to simulate several low-temperature plasma configurations, including a gas switch for high-power AC/DC conversion, a glow discharge and a Hall thruster. Simulation results will be presented with an emphasis on code comparison and validation against experiment. High-voltage, direct-current (HVDC) power transmission is becoming more common as it can reduce construction costs and power losses. Solid-state power-electronics devices are presently used, but it has been proposed that gas switches could become a compact, less costly, alternative. A gas-switch conversion device would be based on a glow discharge, with a magnetically insulated cold cathode. Its operation is similar to that of a sputtering magnetron, but with much higher pressure (0.1 to 0.3 Torr) in order to achieve high current density. We have performed 1D (axial) and 2D (axial/radial) simulations of such a gas switch using LSP. The 1D results were compared with results from the EDIPIC code. To test and compare the collision models used by the LSP and EDIPIC codes in more detail, a validation exercise was performed for the cathode fall of a glow discharge. We will also present some 2D (radial/azimuthal) LSP simulations of a Hall thruster. The information, data, or work presented herein was funded in part by the Advanced Research Projects Agency-Energy (ARPA-E), U.S. Department of Energy, under Award Number DE-AR0000298.

ASC Weekly News Notes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Womble, David E.

Unified collision operator demonstrated for both radiation transport and PIC-DSMC. A side-by-side comparison between the DSMC method and the radiation transport method was conducted for photon attenuation in the atmosphere over 2 kilometers in physical distance with a reduction of photon density of six orders of magnitude. Both DSMC and traditional radiation transport agreed with theory to two digits. This indicates that PIC-DSMC operators can be unified with the radiation transport collision operators into a single code base and that physics kernels can remain unique to the actual collision pairs. This simulation example provides an initial validation of the unifiedmore » collision theory approach that will later be implemented into EMPIRE.« less

OSIRIS-REx NASA Social

NASA Image and Video Library

2016-09-07

Daniel Glavin, OSIRIS-REx co-investigator at NASA’s Goddard Space Flight Center in Greenbelt, Maryland, talks to social media followers during a NASA Social in the Operations Support Building II at the agency’s Kennedy Space Center in Florida. The presentation took place before launch of the agency’s Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer, or OSIRIS-REx spacecraft.

OSIRIS-REx NASA Social

NASA Image and Video Library

2016-09-07

Tim Linn, chief system engineer with Lockheed Martin, discusses the unique design of the OSIRIS-REx spacecraft during a NASA Social with social media followers in the Operations Support Building II at NASA’s Kennedy Space Center in Florida. The presentation took place before launch of the agency’s Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer, or OSIRIS-REx spacecraft.

An efficient and portable SIMD algorithm for charge/current deposition in Particle-In-Cell codes

DOE PAGES

Vincenti, H.; Lobet, M.; Lehe, R.; ...

2016-09-19

In current computer architectures, data movement (from die to network) is by far the most energy consuming part of an algorithm (≈20pJ/word on-die to ≈10,000 pJ/word on the network). To increase memory locality at the hardware level and reduce energy consumption related to data movement, future exascale computers tend to use many-core processors on each compute nodes that will have a reduced clock speed to allow for efficient cooling. To compensate for frequency decrease, machine vendors are making use of long SIMD instruction registers that are able to process multiple data with one arithmetic operator in one clock cycle. SIMD registermore » length is expected to double every four years. As a consequence, Particle-In-Cell (PIC) codes will have to achieve good vectorization to fully take advantage of these upcoming architectures. In this paper, we present a new algorithm that allows for efficient and portable SIMD vectorization of current/charge deposition routines that are, along with the field gathering routines, among the most time consuming parts of the PIC algorithm. Our new algorithm uses a particular data structure that takes into account memory alignment constraints and avoids gather/scat;ter instructions that can significantly affect vectorization performances on current CPUs. The new algorithm was successfully implemented in the 3D skeleton PIC code PICSAR and tested on Haswell Xeon processors (AVX2-256 bits wide data registers). Results show a factor of ×2 to ×2.5 speed-up in double precision for particle shape factor of orders 1–3. The new algorithm can be applied as is on future KNL (Knights Landing) architectures that will include AVX-512 instruction sets with 512 bits register lengths (8 doubles/16 singles). Program summary Program Title: vec_deposition Program Files doi:http://dx.doi.org/10.17632/nh77fv9k8c.1 Licensing provisions: BSD 3-Clause Programming language: Fortran 90 External routines/libraries:  OpenMP > 4.0 Nature of problem: Exascale architectures will have many-core processors per node with long vector data registers capable of performing one single instruction on multiple data during one clock cycle. Data register lengths are expected to double every four years and this pushes for new portable solutions for efficiently vectorizing Particle-In-Cell codes on these future many-core architectures. One of the main hotspot routines of the PIC algorithm is the current/charge deposition for which there is no efficient and portable vector algorithm. Solution method: Here we provide an efficient and portable vector algorithm of current/charge deposition routines that uses a new data structure, which significantly reduces gather/scatter operations. Vectorization is controlled using OpenMP 4.0 compiler directives for vectorization which ensures portability across different architectures. Restrictions: Here we do not provide the full PIC algorithm with an executable but only vector routines for current/charge deposition. These scalar/vector routines can be used as library routines in your 3D Particle-In-Cell code. However, to get the best performances out of vector routines you have to satisfy the two following requirements: (1) Your code should implement particle tiling (as explained in the manuscript) to allow for maximized cache reuse and reduce memory accesses that can hinder vector performances. The routines can be used directly on each particle tile. (2) You should compile your code with a Fortran 90 compiler (e.g Intel, gnu or cray) and provide proper alignment flags and compiler alignment directives (more details in README file).« less

An efficient and portable SIMD algorithm for charge/current deposition in Particle-In-Cell codes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vincenti, H.; Lobet, M.; Lehe, R.

In current computer architectures, data movement (from die to network) is by far the most energy consuming part of an algorithm (≈20pJ/word on-die to ≈10,000 pJ/word on the network). To increase memory locality at the hardware level and reduce energy consumption related to data movement, future exascale computers tend to use many-core processors on each compute nodes that will have a reduced clock speed to allow for efficient cooling. To compensate for frequency decrease, machine vendors are making use of long SIMD instruction registers that are able to process multiple data with one arithmetic operator in one clock cycle. SIMD registermore » length is expected to double every four years. As a consequence, Particle-In-Cell (PIC) codes will have to achieve good vectorization to fully take advantage of these upcoming architectures. In this paper, we present a new algorithm that allows for efficient and portable SIMD vectorization of current/charge deposition routines that are, along with the field gathering routines, among the most time consuming parts of the PIC algorithm. Our new algorithm uses a particular data structure that takes into account memory alignment constraints and avoids gather/scat;ter instructions that can significantly affect vectorization performances on current CPUs. The new algorithm was successfully implemented in the 3D skeleton PIC code PICSAR and tested on Haswell Xeon processors (AVX2-256 bits wide data registers). Results show a factor of ×2 to ×2.5 speed-up in double precision for particle shape factor of orders 1–3. The new algorithm can be applied as is on future KNL (Knights Landing) architectures that will include AVX-512 instruction sets with 512 bits register lengths (8 doubles/16 singles). Program summary Program Title: vec_deposition Program Files doi:http://dx.doi.org/10.17632/nh77fv9k8c.1 Licensing provisions: BSD 3-Clause Programming language: Fortran 90 External routines/libraries:  OpenMP > 4.0 Nature of problem: Exascale architectures will have many-core processors per node with long vector data registers capable of performing one single instruction on multiple data during one clock cycle. Data register lengths are expected to double every four years and this pushes for new portable solutions for efficiently vectorizing Particle-In-Cell codes on these future many-core architectures. One of the main hotspot routines of the PIC algorithm is the current/charge deposition for which there is no efficient and portable vector algorithm. Solution method: Here we provide an efficient and portable vector algorithm of current/charge deposition routines that uses a new data structure, which significantly reduces gather/scatter operations. Vectorization is controlled using OpenMP 4.0 compiler directives for vectorization which ensures portability across different architectures. Restrictions: Here we do not provide the full PIC algorithm with an executable but only vector routines for current/charge deposition. These scalar/vector routines can be used as library routines in your 3D Particle-In-Cell code. However, to get the best performances out of vector routines you have to satisfy the two following requirements: (1) Your code should implement particle tiling (as explained in the manuscript) to allow for maximized cache reuse and reduce memory accesses that can hinder vector performances. The routines can be used directly on each particle tile. (2) You should compile your code with a Fortran 90 compiler (e.g Intel, gnu or cray) and provide proper alignment flags and compiler alignment directives (more details in README file).« less

Benchmarking gyrokinetic simulations in a toroidal flux-tube

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Y.; Parker, S. E.; Wan, W.

2013-09-15

A flux-tube model is implemented in the global turbulence code GEM [Y. Chen and S. E. Parker, J. Comput. Phys. 220, 839 (2007)] in order to facilitate benchmarking with Eulerian codes. The global GEM assumes the magnetic equilibrium to be completely given. The initial flux-tube implementation simply selects a radial location as the center of the flux-tube and a radial size of the flux-tube, sets all equilibrium quantities (B, ∇B, etc.) to be equal to the values at the center of the flux-tube, and retains only a linear radial profile of the safety factor needed for boundary conditions. This implementationmore » shows disagreement with Eulerian codes in linear simulations. An alternative flux-tube model based on a complete local equilibrium solution of the Grad-Shafranov equation [J. Candy, Plasma Phys. Controlled Fusion 51, 105009 (2009)] is then implemented. This results in better agreement between Eulerian codes and the particle-in-cell (PIC) method. The PIC algorithm based on the v{sub ||}-formalism [J. Reynders, Ph.D. dissertation, Princeton University, 1992] and the gyrokinetic ion/fluid electron hybrid model with kinetic electron closure [Y. Chan and S. E. Parker, Phys. Plasmas 18, 055703 (2011)] are also implemented in the flux-tube geometry and compared with the direct method for both the ion temperature gradient driven modes and the kinetic ballooning modes.« less

Design Considerations of a Virtual Laboratory for Advanced X-ray Sources

NASA Astrophysics Data System (ADS)

Luginsland, J. W.; Frese, M. H.; Frese, S. D.; Watrous, J. J.; Heileman, G. L.

2004-11-01

The field of scientific computation has greatly advanced in the last few years, resulting in the ability to perform complex computer simulations that can predict the performance of real-world experiments in a number of fields of study. Among the forces driving this new computational capability is the advent of parallel algorithms, allowing calculations in three-dimensional space with realistic time scales. Electromagnetic radiation sources driven by high-voltage, high-current electron beams offer an area to further push the state-of-the-art in high fidelity, first-principles simulation tools. The physics of these x-ray sources combine kinetic plasma physics (electron beams) with dense fluid-like plasma physics (anode plasmas) and x-ray generation (bremsstrahlung). There are a number of mature techniques and software packages for dealing with the individual aspects of these sources, such as Particle-In-Cell (PIC), Magneto-Hydrodynamics (MHD), and radiation transport codes. The current effort is focused on developing an object-oriented software environment using the Rational© Unified Process and the Unified Modeling Language (UML) to provide a framework where multiple 3D parallel physics packages, such as a PIC code (ICEPIC), a MHD code (MACH), and a x-ray transport code (ITS) can co-exist in a system-of-systems approach to modeling advanced x-ray sources. Initial software design and assessments of the various physics algorithms' fidelity will be presented.

Magnetohydrodynamics with Embedded Particle-in-Cell Simulation of Mercury's Magnetosphere

NASA Astrophysics Data System (ADS)

Chen, Y.; Toth, G.; Jia, X.; Gombosi, T. I.; Markidis, S.

2015-12-01

Mercury's magnetosphere is much more dynamic than other planetary magnetospheres because of Mercury's weak intrinsic magnetic field and its proximity to the Sun. Magnetic reconnection and Kelvin-Helmholtz phenomena occur in Mercury's magnetopause and magnetotail at higher frequencies than in other planetary magnetosphere. For instance, chains of flux transfer events (FTEs) on the magnetopause, have been frequentlyobserved by the the MErcury Surface, Space ENvironment, GEochemistry and Ranging (MESSENGER) spacecraft (Slavin et al., 2012). Because ion Larmor radius is comparable to typical spatial scales in Mercury's magnetosphere, finite Larmor radius effects need to be accounted for. In addition, it is important to take in account non-ideal dissipation mechanisms to accurately describe magnetic reconnection. A kinetic approach allows us to model these phenomena accurately. However, kinetic global simulations, even for small-size magnetospheres like Mercury's, are currently unfeasible because of the high computational cost. In this work, we carry out global simulations of Mercury's magnetosphere with the recently developed MHD-EPIC model, which is a two-way coupling of the extended magnetohydrodynamic (XMHD) code BATS-R-US with the implicit Particle-in-Cell (PIC) model iPIC3D. The PIC model can cover the regions where kinetic effects are most important, such as reconnection sites. The BATS-R-US code, on the other hand, can efficiently handle the rest of the computational domain where the MHD or Hall MHD description is sufficient. We will present our preliminary results and comparison with MESSENGER observations.

Sensor Authentication: Embedded Processor Code

DOE Office of Scientific and Technical Information (OSTI.GOV)

Svoboda, John

2012-09-25

Described is the c code running on the embedded Microchip 32bit PIC32MX575F256H located on the INL developed noise analysis circuit board. The code performs the following functions: Controls the noise analysis circuit board preamplifier voltage gains of 1, 10, 100, 000 Initializes the analog to digital conversion hardware, input channel selection, Fast Fourier Transform (FFT) function, USB communications interface, and internal memory allocations Initiates high resolution 4096 point 200 kHz data acquisition Computes complex 2048 point FFT and FFT magnitude. Services Host command set Transfers raw data to Host Transfers FFT result to host Communication error checking

ONIX results: Comparison of grid geometry (BATMAN - ELISE - flat grid)

NASA Astrophysics Data System (ADS)

Revel, Adrien; Mochalskyy, Serhiy; Wünderlich, Dirk; Fantz, Ursel; Minea, Tiberiu

2017-08-01

The 3D PIC-MCC code ONIX is dedicated to the modelling of negative hydrogen or deuterium ion extraction and the co-extracted electrons from the plasma in radio-frequency driven sources. The extraction process highly depends on the plasma characteristics close to the plasma grid where it is difficult to obtain experimental data. ONIX brings valuable insights on the plasma behavior in this area. In the code, the numerical treatment of the boundaries have been improved in order to describe with more accuracy the potential and the electric field in this vicinity. The computation time has been reduced by a factor of 2 and the parallelization efficiency has been highly improved. The influence of the magnetic field in BATMAN on the plasma behaviour has been investigated by comparing two different configurations of the magnet bars producing the filter field (internal magnets: x = 3 cm; external magnets: x = 9 cm). A flat grid geometry for the PG instead of the usual conical grid geometry has been studied to evaluate its impact on the extracted current, especially for the negative ions emitted from the surface of the PG. Finally, the ONIX code has been used for the first 3D PIC calculations ever performed for the ELISE experiment.

Combining electromagnetic gyro-kinetic particle-in-cell simulations with collisions

NASA Astrophysics Data System (ADS)

Slaby, Christoph; Kleiber, Ralf; Könies, Axel

2017-09-01

It has been an open question whether for electromagnetic gyro-kinetic particle-in-cell (PIC) simulations pitch-angle collisions and the recently introduced pullback transformation scheme (Mishchenko et al., 2014; Kleiber et al., 2016) are consistent. This question is positively answered by comparing the PIC code EUTERPE with an approach based on an expansion of the perturbed distribution function in eigenfunctions of the pitch-angle collision operator (Legendre polynomials) to solve the electromagnetic drift-kinetic equation with collisions in slab geometry. It is shown how both approaches yield the same results for the frequency and damping rate of a kinetic Alfvén wave and how the perturbed distribution function is substantially changed by the presence of pitch-angle collisions.

TRANSITION FROM KINETIC TO MHD BEHAVIOR IN A COLLISIONLESS PLASMA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Parashar, Tulasi N.; Matthaeus, William H.; Shay, Michael A.

The study of kinetic effects in heliospheric plasmas requires representation of dynamics at sub-proton scales, but in most cases the system is driven by magnetohydrodynamic (MHD) activity at larger scales. The latter requirement challenges available computational resources, which raises the question of how large such a system must be to exhibit MHD traits at large scales while kinetic behavior is accurately represented at small scales. Here we study this implied transition from kinetic to MHD-like behavior using particle-in-cell (PIC) simulations, initialized using an Orszag–Tang Vortex. The PIC code treats protons, as well as electrons, kinetically, and we address the questionmore » of interest by examining several different indicators of MHD-like behavior.« less

OSIRIS-REx NASA Social

NASA Image and Video Library

2016-09-07

Social media followers were briefed by NASA scientists on asteroids, how they relate to the origins of our solar system and the search for life beyond Earth, during a NASA Social presentation in the Operations Support Building II at the agency’s Kennedy Space Center in Florida. The presentation took place before launch of the agency’s Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer, or OSIRIS-REx spacecraft. From the left, are Jarmaine Ollivierre, OSIRIS-REx lead flight designs with NASA’s Launch Services Program; and Gordon McLemore, with United Launch Alliance (ULA). OSIRIS-REx will launch aboard a ULA Atlas V rocket from Space Launch Complex 41 at NASA’s Kennedy Space Center.

Observation of 1-D time dependent non-propagating laser plasma structures using fluid and PIC codes

NASA Astrophysics Data System (ADS)

Verma, Deepa; Bera, Ratan Kumar; Kumar, Atul; Patel, Bhavesh; Das, Amita

2017-12-01

The manuscript reports the observation of time dependent localized and non-propagating structures in the coupled laser plasma system through 1-D fluid and Particle-In-Cell (PIC) simulations. It is reported that such structures form spontaneously as a result of collision amongst certain exact solitonic solutions. They are seen to survive as coherent entities for a long time up to several hundreds of plasma periods. Furthermore, it is shown that such time dependence can also be artificially recreated by significantly disturbing the delicate balance between the radiation and the density fields required for the exact non-propagating solution obtained by Esirkepov et al., JETP 68(1), 36-41 (1998). The ensuing time evolution is an interesting interplay between kinetic and field energies of the system. The electrostatic plasma oscillations are coupled with oscillations in the electromagnetic field. The inhomogeneity of the background and the relativistic nature, however, invariably produces large amplitude density perturbations leading to its wave breaking. In the fluid simulations, the signature of wave breaking can be discerned by a drop in the total energy which evidently gets lost to the grid. The PIC simulations are observed to closely follow the fluid simulations till the point of wave breaking. However, the total energy in the case of PIC simulations is seen to remain conserved throughout the simulations. At the wave breaking, the particles are observed to acquire thermal kinetic energy in the case of PIC. Interestingly, even after wave breaking, compact coherent structures with trapped radiation inside high-density peaks continue to exist both in PIC and fluid simulations. Although the time evolution does not exactly match in the two simulations as it does prior to the process of wave breaking, the time-dependent features exhibited by the remnant structures are characteristically similar.

Edge Simulation Laboratory Progress and Plans

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cohen, R

The Edge Simulation Laboratory (ESL) is a project to develop a gyrokinetic code for MFE edge plasmas based on continuum (Eulerian) techniques. ESL is a base-program activity of OFES, with an allied algorithm research activity funded by the OASCR base math program. ESL OFES funds directly support about 0.8 FTE of career staff at LLNL, a postdoc and a small fraction of an FTE at GA, and a graduate student at UCSD. In addition the allied OASCR program funds about 1/2 FTE each in the computations directorates at LBNL and LLNL. OFES ESL funding for LLNL and UCSD began inmore » fall 2005, while funding for GA and the math team began about a year ago. ESL's continuum approach is a complement to the PIC-based methods of the CPES Project, and was selected (1) because of concerns about noise issues associated with PIC in the high-density-contrast environment of the edge pedestal, (2) to be able to exploit advanced numerical methods developed for fluid codes, and (3) to build upon the successes of core continuum gyrokinetic codes such as GYRO, GS2 and GENE. The ESL project presently has three components: TEMPEST, a full-f, full-geometry (single-null divertor, or arbitrary-shape closed flux surfaces) code in E, {mu} (energy, magnetic-moment) coordinates; EGK, a simple-geometry rapid-prototype code, presently of; and the math component, which is developing and implementing algorithms for a next-generation code. Progress would be accelerated if we could find funding for a fourth, computer science, component, which would develop software infrastructure, provide user support, and address needs for data handing and analysis. We summarize the status and plans for the three funded activities.« less

Theoretical and computational studies of the sheath of a planar wall

NASA Astrophysics Data System (ADS)

Giraudo, Martina; Camporeale, Enrico; Delzanno, Gian Luca; Lapenta, Giovanni

2012-03-01

We present an investigation of the stability and nonlinear evolution of the sheath of a planar wall. We focus on the electrostatic limit. The stability analysis is conducted with a fluid model where continuity and momentum equations for the electrons and ions are coupled through Poisson's equation. The effect of electron emission from the wall is studied parametrically. Our results show that a sheath instability associated with the emitted electrons can exist. Following Ref. [1], it is interpreted as a Rayleigh-Taylor instability driven by the favorable combination of the sheath electron density gradient and electric field. Fully kinetic Particle-In-Cell (PIC) simulations will also be presented to investigate whether this instability indeed exists and to study the nonlinear effect of electron emission on the sheath profiles. The simulations will be conducted with CPIC, a new electrostatic PIC code that couples the standard PIC algorithm with strategies for generation and adaptation of the computational grid. [4pt] [1] G.L. Delzanno, ``A paradigm for the stability of the plasma sheath against fluid perturbations,'' Phys. Plasmas 18, 103508 (2011).

Multi-scale simulations of space problems with iPIC3D

NASA Astrophysics Data System (ADS)

Lapenta, Giovanni; Bettarini, Lapo; Markidis, Stefano

The implicit Particle-in-Cell method for the computer simulation of space plasma, and its im-plementation in a three-dimensional parallel code, called iPIC3D, are presented. The implicit integration in time of the Vlasov-Maxwell system removes the numerical stability constraints and enables kinetic plasma simulations at magnetohydrodynamics scales. Simulations of mag-netic reconnection in plasma are presented to show the effectiveness of the algorithm. In particular we will show a number of simulations done for large scale 3D systems using the physical mass ratio for Hydrogen. Most notably one simulation treats kinetically a box of tens of Earth radii in each direction and was conducted using about 16000 processors of the Pleiades NASA computer. The work is conducted in collaboration with the MMS-IDS theory team from University of Colorado (M. Goldman, D. Newman and L. Andersson). Reference: Stefano Markidis, Giovanni Lapenta, Rizwan-uddin Multi-scale simulations of plasma with iPIC3D Mathematics and Computers in Simulation, Available online 17 October 2009, http://dx.doi.org/10.1016/j.matcom.2009.08.038

Computational Modeling of Ultrafast Pulse Propagation in Nonlinear Optical Materials

NASA Technical Reports Server (NTRS)

Goorjian, Peter M.; Agrawal, Govind P.; Kwak, Dochan (Technical Monitor)

1996-01-01

There is an emerging technology of photonic (or optoelectronic) integrated circuits (PICs or OEICs). In PICs, optical and electronic components are grown together on the same chip. rib build such devices and subsystems, one needs to model the entire chip. Accurate computer modeling of electromagnetic wave propagation in semiconductors is necessary for the successful development of PICs. More specifically, these computer codes would enable the modeling of such devices, including their subsystems, such as semiconductor lasers and semiconductor amplifiers in which there is femtosecond pulse propagation. Here, the computer simulations are made by solving the full vector, nonlinear, Maxwell's equations, coupled with the semiconductor Bloch equations, without any approximations. The carrier is retained in the description of the optical pulse, (i.e. the envelope approximation is not made in the Maxwell's equations), and the rotating wave approximation is not made in the Bloch equations. These coupled equations are solved to simulate the propagation of femtosecond optical pulses in semiconductor materials. The simulations describe the dynamics of the optical pulses, as well as the interband and intraband.

Alfvénic wave packets collision in a kinetic plasma

NASA Astrophysics Data System (ADS)

Pezzi, Oreste; Parashar, Tulasi N.; Servidio, Sergio; Valentini, Francesco; Malara, Francesco; Matthaeus, William H.; Veltri, Pierluigi

2016-04-01

The problem of two colliding and counter-propagating Alfvénic wave packets has been investigated in detail since the late Seventies. In particular Moffatt [1] and Parker [2] showed that, in the framework of the incompressible magnetohydrodynamics (MHD), nonlinear interactions can develop only during the overlapping of the two packets. Here we describe a similar problem in the framework of the kinetic physics. The collision of two quasi-Alfvénic packets has been analyzed by means of MHD, Hall-MHD and kinetic simulations performed with two different hybrid codes: a PIC code [3] and a Vlasov-Maxwell code [4]. Due to the huge computational cost, only a 2D-3V phase space is allowed (two dimensions in the physical space, three dimensions in the velocity space). Preliminary results suggest that, as well as in the MHD case, the most relevant nonlinear effects occur during the overlapping of the two packets. For both the PIC and Vlasov cases, strong temperature anisotropies are present during the evolution of the wave packets. Moreover, due to the absence of numerical noise, Vlasov simulations show that the collision of the counter-propagating solitary waves produces a significant beam in the velocity distribution functions [5], which, instead, cannot be appreciated in PIC simulations. We remark that, beyond the interest of studying a well-known MHD problem in the realm of the kinetic physics, our results allows also to compare different numerical codes. [1] H.K. Moffatt, Field generation in electrically conducting fluids (Cambridge University Press, 1978). [2] E.N. Parker, Cosmical magnetic fields: their origin and their activity (Oxford University Press, 1979). [3] T.N. Parashar, M.A. Shay, P.A. Cassak and W.H. Matthaeus, Physics of Plasmas 16, 032310 (2009). [4] F. Valentini, P. Trávníček, F. Califano, P. Hellinger & A. Mangeney, Journal of Computational Physics 225, 753-770 (2007). [5] J. He, C. Tu, E. Marsch, C.H. Chen, L. Wang, Z. Pei, L. Zhang, C.S. Salem and S.D. Bale, The Astrophysical Journal Letters 813, L30 (2015).

Collisions of two Alfvénic wave packets in a kinetic plasma

NASA Astrophysics Data System (ADS)

Pezzi, O.; Servidio, S.; Valentini, F.; Parashar, T.; Malara, F.; Matthaeus, W. H.; Veltri, P.

2016-12-01

The problem of two colliding and counter-propagating Alfvénic wave packets has been investigated in detail since the late Seventies. In particular Moffatt [1] and Parker [2] showed that, in the framework of the incompressible magnetohydrodynamics (MHD), nonlinear interactions can develop only during the overlapping of the two packets. Here we describe a similar problem in the framework of the kinetic physics. The collision of two quasi-Alfvénic packets has been analyzed by means of MHD, Hall-MHD and kinetic simulations performed with two different hybrid codes: a PIC code [3] and a Vlasov-Maxwell code [4]. Due to the huge computational cost, only a 2D-3V phase space is allowed (two dimensions in the physical space, three dimensions in the velocity space). Preliminary results suggest that, as well as in the MHD case, the most relevant nonlinear effects occur during the overlapping of the two packets. For both the PIC and Vlasov cases, strong temperature anisotropies are present during the evolution of the wave packets. Moreover, due to the absence of numerical noise, Vlasov simulations show that the collision of the counter-propagating solitary waves produces a significant beam in the velocity distribution functions [5], which, instead, cannot be appreciated in PIC simulations. We remark that, beyond the interest of studying a well-known MHD problem in the realm of the kinetic physics, our results allows also to compare different numerical codes. [1] H.K. Moffatt, Field generation in electrically conducting fluids (Cambridge University Press, 1978). [2] E.N. Parker, Cosmical magnetic fields: their origin and their activity (Oxford University Press, 1979). [3] T.N. Parashar, M.A. Shay, P.A. Cassak and W.H. Matthaeus, Physics of Plasmas 16, 032310 (2009). [4] F. Valentini, P. Trávníček, F. Califano, P. Hellinger & A. Mangeney, Journal of Computational Physics 225, 753-770 (2007). [5] J. He, C. Tu, E. Marsch, C.H. Chen, L. Wang, Z. Pei, L. Zhang, C.S. Salem and S.D. Bale, The Astrophysical Journal Letters 813, L30 (2015).

DOE Office of Scientific and Technical Information (OSTI.GOV)

Madduri, Kamesh; Im, Eun-Jin; Ibrahim, Khaled Z.

The next decade of high-performance computing (HPC) systems will see a rapid evolution and divergence of multi- and manycore architectures as power and cooling constraints limit increases in microprocessor clock speeds. Understanding efficient optimization methodologies on diverse multicore designs in the context of demanding numerical methods is one of the greatest challenges faced today by the HPC community. In this paper, we examine the efficient multicore optimization of GTC, a petascale gyrokinetic toroidal fusion code for studying plasma microturbulence in tokamak devices. For GTC’s key computational components (charge deposition and particle push), we explore efficient parallelization strategies across a broadmore » range of emerging multicore designs, including the recently-released Intel Nehalem-EX, the AMD Opteron Istanbul, and the highly multithreaded Sun UltraSparc T2+. We also present the first study on tuning gyrokinetic particle-in-cell (PIC) algorithms for graphics processors, using the NVIDIA C2050 (Fermi). Our work discusses several novel optimization approaches for gyrokinetic PIC, including mixed-precision computation, particle binning and decomposition strategies, grid replication, SIMDized atomic floating-point operations, and effective GPU texture memory utilization. Overall, we achieve significant performance improvements of 1.3–4.7× on these complex PIC kernels, despite the inherent challenges of data dependency and locality. Finally, our work also points to several architectural and programming features that could significantly enhance PIC performance and productivity on next-generation architectures.« less

Computation of an ESD-induced E-field Envirnoment and Definition of a Current Injector Test set-up at Equipment Level

NASA Astrophysics Data System (ADS)

Marque, J. P.; Issac, F.; Parmantier, J. P.; Bertuol, S.

1998-11-01

The ESD-induced electromagnetic field on a S/C is computed using the 3D PIC code GEODE. Typical E-field waveforms are deduced and a new susceptibility test at equipment level is proposed as an alternative to the plane wave approach.

Optical Navigation Simulation and Performance Analysis for Osiris-Rex Proximity Operations

NASA Technical Reports Server (NTRS)

Jackman, Coralie D.; Nelson, Derek S.; Mccarthy, Leilah K.; Liounis, Andrew J.; Leonard, Jason M.; Antreasian, Peter G.; Getzandanner, Kenneth M.; Moreau, Michael C.

2017-01-01

The OSIRIS-REx mission timeline with OpNav milestones is presented in Figure 1. The first three proximity operations (ProxOps) mission phases focus on Navigation. During these phases, OSIRIS-REx approaches Bennu, conducts equatorial and polar flybys in Preliminary Survey, and inserts into the first mission orbit: Orbit A. During these phases, the OpNav techniques evolve from point-source to resolved-body centroiding to landmark tracking.

Retrieval of stratospheric ozone and nitrogen dioxide profiles from Odin Optical Spectrograph and Infrared Imager System (OSIRIS) limb-scattered sunlight measurements

NASA Astrophysics Data System (ADS)

Haley, Craig Stuart

2009-12-01

Key to understanding and predicting the effects of global environmental problems such as ozone depletion and global warming is a detailed understanding of the atmospheric processes, both dynamical and chemical. Essential to this understanding are accurate global data sets of atmospheric constituents with adequate temporal and spatial (vertical and horizontal) resolutions. For this purpose the Canadian satellite instrument OSIRIS (Optical Spectrograph and Infrared Imager System) was launched on the Odin satellite in 2001. OSIRIS is primarily designed to measure minor stratospheric constituents, including ozone (O3) and nitrogen dioxide (NO2), employing the novel limb-scattered sunlight technique, which can provide both good vertical resolution and near global coverage. This dissertation presents a method to retrieve stratospheric O 3 and NO2 from the OSIRIS limb-scatter observations. The retrieval method incorporates an a posteriori optimal estimator combined with an intermediate spectral analysis, specifically differential optical absorption spectroscopy (DOAS). A detailed description of the retrieval method is presented along with the results of a thorough error analysis and a geophysical validation exercise. It is shown that OSIRIS limb-scatter observations successfully produce accurate stratospheric O3 and NO2 number density profiles throughout the stratosphere, clearly demonstrating the strength of the limb-scatter technique. The OSIRIS observations provide an extremely useful data set that is of particular importance for studies of the chemistry of the middle atmosphere. The long OSIRIS record of stratospheric ozone and nitrogen dioxide may also prove useful for investigating variability and trends.

SPECT3D - A multi-dimensional collisional-radiative code for generating diagnostic signatures based on hydrodynamics and PIC simulation output

NASA Astrophysics Data System (ADS)

MacFarlane, J. J.; Golovkin, I. E.; Wang, P.; Woodruff, P. R.; Pereyra, N. A.

2007-05-01

SPECT3D is a multi-dimensional collisional-radiative code used to post-process the output from radiation-hydrodynamics (RH) and particle-in-cell (PIC) codes to generate diagnostic signatures (e.g. images, spectra) that can be compared directly with experimental measurements. This ability to post-process simulation code output plays a pivotal role in assessing the reliability of RH and PIC simulation codes and their physics models. SPECT3D has the capability to operate on plasmas in 1D, 2D, and 3D geometries. It computes a variety of diagnostic signatures that can be compared with experimental measurements, including: time-resolved and time-integrated spectra, space-resolved spectra and streaked spectra; filtered and monochromatic images; and X-ray diode signals. Simulated images and spectra can include the effects of backlighters, as well as the effects of instrumental broadening and time-gating. SPECT3D also includes a drilldown capability that shows where frequency-dependent radiation is emitted and absorbed as it propagates through the plasma towards the detector, thereby providing insights on where the radiation seen by a detector originates within the plasma. SPECT3D has the capability to model a variety of complex atomic and radiative processes that affect the radiation seen by imaging and spectral detectors in high energy density physics (HEDP) experiments. LTE (local thermodynamic equilibrium) or non-LTE atomic level populations can be computed for plasmas. Photoabsorption rates can be computed using either escape probability models or, for selected 1D and 2D geometries, multi-angle radiative transfer models. The effects of non-thermal (i.e. non-Maxwellian) electron distributions can also be included. To study the influence of energetic particles on spectra and images recorded in intense short-pulse laser experiments, the effects of both relativistic electrons and energetic proton beams can be simulated. SPECT3D is a user-friendly software package that runs on Windows, Linux, and Mac platforms. A parallel version of SPECT3D is supported for Linux clusters for large-scale calculations. We will discuss the major features of SPECT3D, and present example results from simulations and comparisons with experimental data.

The OSIRIS-REx Asteroid Sample Return Mission Operations Design

NASA Technical Reports Server (NTRS)

Gal-Edd, Jonathan S.; Cheuvront, Allan

2015-01-01

OSIRIS-REx is an acronym that captures the scientific objectives: Origins, Spectral Interpretation, Resource Identification, and Security-Regolith Explorer. OSIRIS-REx will thoroughly characterize near-Earth asteroid Bennu (Previously known as 1019551999 RQ36). The OSIRIS-REx Asteroid Sample Return Mission delivers its science using five instruments and radio science along with the Touch-And-Go Sample Acquisition Mechanism (TAGSAM). All of the instruments and data analysis techniques have direct heritage from flown planetary missions. The OSIRIS-REx mission employs a methodical, phased approach to ensure success in meeting the mission's science requirements. OSIRIS-REx launches in September 2016, with a backup launch period occurring one year later. Sampling occurs in 2019. The departure burn from Bennu occurs in March 2021. On September 24, 2023, the Sample Return Capsule (SRC) lands at the Utah Test and Training Range (UTTR). Stardust heritage procedures are followed to transport the SRC to Johnson Space Center, where the samples are removed and delivered to the OSIRIS-REx curation facility. After a six-month preliminary examination period the mission will produce a catalog of the returned sample, allowing the worldwide community to request samples for detailed analysis. Traveling and returning a sample from an Asteroid that has not been explored before requires unique operations consideration. The Design Reference Mission (DRM) ties together spacecraft, instrument and operations scenarios. Asteroid Touch and Go (TAG) has various options varying from ground only to fully automated (natural feature tracking). Spacecraft constraints such as thermo and high gain antenna pointing impact the timeline. The mission is sensitive to navigation errors, so a late command update has been implemented. The project implemented lessons learned from other "small body" missions. The key lesson learned was 'expect the unexpected' and implement planning tools early in the lifecycle. This paper summarizes the ground and spacecraft design as presented at OSIRIS-REx Critical Design Review(CDR) held April 2014.

Rise time of proton cut-off energy in 2D and 3D PIC simulations

NASA Astrophysics Data System (ADS)

Babaei, J.; Gizzi, L. A.; Londrillo, P.; Mirzanejad, S.; Rovelli, T.; Sinigardi, S.; Turchetti, G.

2017-04-01

The Target Normal Sheath Acceleration regime for proton acceleration by laser pulses is experimentally consolidated and fairly well understood. However, uncertainties remain in the analysis of particle-in-cell simulation results. The energy spectrum is exponential with a cut-off, but the maximum energy depends on the simulation time, following different laws in two and three dimensional (2D, 3D) PIC simulations so that the determination of an asymptotic value has some arbitrariness. We propose two empirical laws for the rise time of the cut-off energy in 2D and 3D PIC simulations, suggested by a model in which the proton acceleration is due to a surface charge distribution on the target rear side. The kinetic energy of the protons that we obtain follows two distinct laws, which appear to be nicely satisfied by PIC simulations, for a model target given by a uniform foil plus a contaminant layer that is hydrogen-rich. The laws depend on two parameters: the scaling time, at which the energy starts to rise, and the asymptotic cut-off energy. The values of the cut-off energy, obtained by fitting 2D and 3D simulations for the same target and laser pulse configuration, are comparable. This suggests that parametric scans can be performed with 2D simulations since 3D ones are computationally very expensive, delegating their role only to a correspondence check. In this paper, the simulations are carried out with the PIC code ALaDyn by changing the target thickness L and the incidence angle α, with a fixed a0 = 3. A monotonic dependence, on L for normal incidence and on α for fixed L, is found, as in the experimental results for high temporal contrast pulses.

The REgolith X-Ray Imaging Spectrometer (REXIS) for OSIRIS-REx: identifying regional elemental enrichment on asteroids

NASA Astrophysics Data System (ADS)

Allen, Branden; Grindlay, Jonathan; Hong, Jaesub; Binzel, Richard P.; Masterson, Rebecca; Inamdar, Niraj K.; Chodas, Mark; Smith, Matthew W.; Bautz, Marshall W.; Kissel, Steven E.; Villasenor, Joel; Oprescu, Miruna; Induni, Nicholas

2013-09-01

The OSIRIS-REx Mission was selected under the NASA New Frontiers program and is scheduled for launch in September of 2016 for a rendezvous with, and collection of a sample from the surface of asteroid Bennu in 2019. 101955 Bennu (previously 1999 RQ36) is an Apollo (near-Earth) asteroid originally discovered by the LINEAR project in 1999 which has since been classified as a potentially hazardous near-Earth object. The REgolith X-Ray Imaging Spectrometer (REXIS) was proposed jointly by MIT and Harvard and was subsequently accepted as a student led instrument for the determination of the elemental composition of the asteroid's surface as well as the surface distribution of select elements through solar induced X-ray fluorescence. REXIS consists of a detector plane that contains 4 X-ray CCDs integrated into a wide field coded aperture telescope with a focal length of 20 em for the detection of regions with enhanced abundance in key elements at 50 m scales. Elemental surface distributions of approximately 50-200 m scales can be detected using the instrument as a simple collimator. An overview of the observation strategy of the REXIS instrument and expected performance are presented here.

Development of CCDs for REXIS on OSIRIS-REx

NASA Astrophysics Data System (ADS)

Ryu, Kevin K.; Burke, Barry E.; Clark, Harry R.; Lambert, Renee D.; O'Brien, Peter; Suntharalingam, Vyshnavi; Ward, Christopher M.; Warner, Keith; Bautz, Mark W.; Binzel, Richard P.; Kissel, Steven E.; Masterson, Rebecca A.

2014-07-01

The Regolith x-ray Imaging Spectrometer (REXIS) is a coded-aperture soft x-ray imaging instrument on the OSIRIS-REx spacecraft to be launched in 2016. The spacecraft will fly to and orbit the near-Earth asteroid Bennu, while REXIS maps the elemental distribution on the asteroid using x-ray fluorescence. The detector consists of a 2×2 array of backilluminated 1k×1k frame transfer CCDs with a flight heritage to Suzaku and Chandra. The back surface has a thin p+-doped layer deposited by molecular-beam epitaxy (MBE) for maximum quantum efficiency and energy resolution at low x-ray energies. The CCDs also feature an integrated optical-blocking filter (OBF) to suppress visible and near-infrared light. The OBF is an aluminum film deposited directly on the CCD back surface and is mechanically more robust and less absorptive of x-rays than the conventional free-standing aluminum-coated polymer films. The CCDs have charge transfer inefficiencies of less than 10-6, and dark current of 1e-/pixel/second at the REXIS operating temperature of -60 °C. The resulting spectral resolution is 115 eV at 2 KeV. The extinction ratio of the filter is ~1012 at 625 nm.

The OSIRIS-REx Mission Sample Site Selection Process

NASA Astrophysics Data System (ADS)

Beshore, Edward C.; Lauretta, Dante

2014-11-01

In September of 2016, the OSIRIS-REx (Origins, Spectral Interpretation, Resource Identification, Security, REgolith eXplorer) spacecraft will depart for asteroid (101955) Bennu, and in doing so, will turn an important corner in the exploration of the solar system. After arriving at Bennu in the fall of 2018, OSIRIS-REx will undertake a program of observations designed to select a site suitable for retrieving a sample that will be returned to the Earth in 2023. The third mission in NASA’s New Frontiers program, OSIRIS-REx will return over 60 grams from Bennu’s surface.OSIRIS-REx is unique because the science team will have an operational role to play in preparing data products needed to select a sample site. These include products used to ensure flight system safety — topographic maps and shape models, temperature measurements, maps of hazards — as well as assessments of sampleability and science value. The timing and production of these will be presented, as will the high-level decision-making tools and processes for the interim and final site selection processes.

BENNU’S JOURNEY Poster

NASA Image and Video Library

2017-12-08

The Origins Spectral Interpretation Resource Identification Security -- Regolith Explorer spacecraft (OSIRIS-REx) will travel to a near-Earth asteroid, called Bennu, and bring a sample back to Earth for study. The mission will help scientists investigate how planets formed and how life began, as well as improve our understanding of asteroids that could impact Earth. OSIRIS-REx is scheduled for launch in late 2016. As planned, the spacecraft will reach its asteroid target in 2018 and return a sample to Earth in 2023. Watch the full video: youtu.be/gtUgarROs08 Learn more about NASA’s OSIRIS-REx mission and the making of Bennu’s Journey: www.nasa.gov/content/goddard/bennus-journey/ More information on the OSIRIS-REx mission is available at: www.nasa.gov/mission_pages/osiris-rex/index.html www.asteroidmission.org NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

Thermal assessment of sunlight impinging on OSIRIS-REx OCAMS PolyCam, OTES, and IMU-sunshade MLI blankets in flight

NASA Astrophysics Data System (ADS)

Choi, Michael K.

2017-09-01

The NASA Origins, Spectral Interpretation, Resource Identification, Security, Regolith Explorer (OSIRIS-REx) spacecraft was successfully launched into orbit on September 8, 2016. It is traveling to a near-Earth asteroid (101955) Bennu, study it in detail, and bring back a pristine sample to Earth for scientific analyses. At the Outbound Cruise nominal spacecraft attitude, with Sun on +X, sunlight impinges on the OSIRIS-REx camera suite (OCAMS) PolyCam sunshade multilayer insulation (MLI) with microporous black polytetrafluoroethylene (PTFE), a portion of the PolyCam optics support tube (MLI with germanium black Kapton (GBK)), a portion of the OSIRIS-REx Thermal Emission Spectrometer (OTES) sunshade (MLI with GBK), the Inertia Measurement Unit (IMU) sunshade (MLI with GBK), and the OSIRIS-REx Laser Altimeter (OLA) sunshade (MLI with GBK). Sunlight is reflected or scattered by the above MLIs to the other components on the forward (+Z) deck. It illuminates the forward deck. A detailed thermal assessment on the solar impingement has been performed for the Proximity Ops at the asteroid, Touch-and-Go sample acquisition, and Return Cruise mission phases.

Drift-corrected Odin-OSIRIS ozone product: algorithm and updated stratospheric ozone trends

NASA Astrophysics Data System (ADS)

Bourassa, Adam E.; Roth, Chris Z.; Zawada, Daniel J.; Rieger, Landon A.; McLinden, Chris A.; Degenstein, Douglas A.

2018-01-01

A small long-term drift in the Optical Spectrograph and Infrared Imager System (OSIRIS) stratospheric ozone product, manifested mostly since 2012, is quantified and attributed to a changing bias in the limb pointing knowledge of the instrument. A correction to this pointing drift using a predictable shape in the measured limb radiance profile is implemented and applied within the OSIRIS retrieval algorithm. This new data product, version 5.10, displays substantially better both long- and short-term agreement with Microwave Limb Sounder (MLS) ozone throughout the stratosphere due to the pointing correction. Previously reported stratospheric ozone trends over the time period 1984-2013, which were derived by merging the altitude-number density ozone profile measurements from the Stratospheric Aerosol and Gas Experiment (SAGE) II satellite instrument (1984-2005) and from OSIRIS (2002-2013), are recalculated using the new OSIRIS version 5.10 product and extended to 2017. These results still show statistically significant positive trends throughout the upper stratosphere since 1997, but at weaker levels that are more closely in line with estimates from other data records.

The Activity of Comet 67P/Churyumov-Gerasimenko as Seen by Rosetta/OSIRIS

NASA Astrophysics Data System (ADS)

Sierks, H.; Barbieri, C.; Lamy, P. L.; Rodrigo, R.; Rickman, H.; Koschny, D.

2015-12-01

The Rosetta mission of the European Space Agency arrived on August 6, 2014, at the target comet 67P/Churyumov-Gerasimenko. OSIRIS (Optical, Spectroscopic, and Infrared Remote Imaging System) is the scientific imaging system onboard Rosetta. OSIRIS consists of a Narrow Angle Camera (NAC) for the nucleus surface and dust studies and a Wide Angle Camera (WAC) for the wide field gas and dust coma investigations. OSIRIS observed the coma and the nucleus of comet 67P/C-G during approach, arrival, and landing of PHILAE. OSIRIS continued comet monitoring and mapping of surface and activity in 2015 with close fly-bys with high resolution and remote, wide angle observations. The scientific results reveal a nucleus with two lobes and varied morphology. Active regions are located at steep cliffs and collapsed pits which form collimated gas jets. Dust is accelerated by the gas, forming bright jet filaments and the large scale, diffuse coma of the comet. We will present activity and surface changes observed in the Northern and Southern hemisphere and around perihelion passage.

Modeling of neutral entrainment in an FRC thruster

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brackbill, Jeremiah; Gimelshein, Natalia; Gimelshein, Sergey

2012-11-27

Neutral entrainment in a field reversed configuration thruster is modeled numerically with an implicit PIC code extended to include thermal and chemical interactions between plasma and neutral particles. The contribution of charge exchange and electron impact ionization reactions is analyzed, and the sensitivity of the entrainment efficiency to the plasmoid translation velocity and neutral density is evaluated.

Improvements of the particle-in-cell code EUTERPE for petascaling machines

NASA Astrophysics Data System (ADS)

Sáez, Xavier; Soba, Alejandro; Sánchez, Edilberto; Kleiber, Ralf; Castejón, Francisco; Cela, José M.

2011-09-01

In the present work we report some performance measures and computational improvements recently carried out using the gyrokinetic code EUTERPE (Jost, 2000 [1] and Jost et al., 1999 [2]), which is based on the general particle-in-cell (PIC) method. The scalability of the code has been studied for up to sixty thousand processing elements and some steps towards a complete hybridization of the code were made. As a numerical example, non-linear simulations of Ion Temperature Gradient (ITG) instabilities have been carried out in screw-pinch geometry and the results are compared with earlier works. A parametric study of the influence of variables (step size of the time integrator, number of markers, grid size) on the quality of the simulation is presented.

The Mediator complex and transcription regulation

PubMed Central

Poss, Zachary C.; Ebmeier, Christopher C.

2013-01-01

The Mediator complex is a multi-subunit assembly that appears to be required for regulating expression of most RNA polymerase II (pol II) transcripts, which include protein-coding and most non-coding RNA genes. Mediator and pol II function within the pre-initiation complex (PIC), which consists of Mediator, pol II, TFIIA, TFIIB, TFIID, TFIIE, TFIIF and TFIIH and is approximately 4.0 MDa in size. Mediator serves as a central scaffold within the PIC and helps regulate pol II activity in ways that remain poorly understood. Mediator is also generally targeted by sequence-specific, DNA-binding transcription factors (TFs) that work to control gene expression programs in response to developmental or environmental cues. At a basic level, Mediator functions by relaying signals from TFs directly to the pol II enzyme, thereby facilitating TF-dependent regulation of gene expression. Thus, Mediator is essential for converting biological inputs (communicated by TFs) to physiological responses (via changes in gene expression). In this review, we summarize an expansive body of research on the Mediator complex, with an emphasis on yeast and mammalian complexes. We focus on the basics that underlie Mediator function, such as its structure and subunit composition, and describe its broad regulatory influence on gene expression, ranging from chromatin architecture to transcription initiation and elongation, to mRNA processing. We also describe factors that influence Mediator structure and activity, including TFs, non-coding RNAs and the CDK8 module. PMID:24088064

Gyrokinetic particle-in-cell optimization on emerging multi- and manycore platforms

DOE PAGES

Madduri, Kamesh; Im, Eun-Jin; Ibrahim, Khaled Z.; ...

2011-03-02

The next decade of high-performance computing (HPC) systems will see a rapid evolution and divergence of multi- and manycore architectures as power and cooling constraints limit increases in microprocessor clock speeds. Understanding efficient optimization methodologies on diverse multicore designs in the context of demanding numerical methods is one of the greatest challenges faced today by the HPC community. In this paper, we examine the efficient multicore optimization of GTC, a petascale gyrokinetic toroidal fusion code for studying plasma microturbulence in tokamak devices. For GTC’s key computational components (charge deposition and particle push), we explore efficient parallelization strategies across a broadmore » range of emerging multicore designs, including the recently-released Intel Nehalem-EX, the AMD Opteron Istanbul, and the highly multithreaded Sun UltraSparc T2+. We also present the first study on tuning gyrokinetic particle-in-cell (PIC) algorithms for graphics processors, using the NVIDIA C2050 (Fermi). Our work discusses several novel optimization approaches for gyrokinetic PIC, including mixed-precision computation, particle binning and decomposition strategies, grid replication, SIMDized atomic floating-point operations, and effective GPU texture memory utilization. Overall, we achieve significant performance improvements of 1.3–4.7× on these complex PIC kernels, despite the inherent challenges of data dependency and locality. Finally, our work also points to several architectural and programming features that could significantly enhance PIC performance and productivity on next-generation architectures.« less

Global Particle-in-Cell Simulations of Mercury's Magnetosphere

NASA Astrophysics Data System (ADS)

Schriver, D.; Travnicek, P. M.; Lapenta, G.; Amaya, J.; Gonzalez, D.; Richard, R. L.; Berchem, J.; Hellinger, P.

2017-12-01

Spacecraft observations of Mercury's magnetosphere have shown that kinetic ion and electron particle effects play a major role in the transport, acceleration, and loss of plasma within the magnetospheric system. Kinetic processes include reconnection, the breakdown of particle adiabaticity and wave-particle interactions. Because of the vast range in spatial scales involved in magnetospheric dynamics, from local electron Debye length scales ( meters) to solar wind/planetary magnetic scale lengths (tens to hundreds of planetary radii), fully self-consistent kinetic simulations of a global planetary magnetosphere remain challenging. Most global simulations of Earth's and other planet's magnetosphere are carried out using MHD, enhanced MHD (e.g., Hall MHD), hybrid, or a combination of MHD and particle in cell (PIC) simulations. Here, 3D kinetic self-consistent hybrid (ion particle, electron fluid) and full PIC (ion and electron particle) simulations of the solar wind interaction with Mercury's magnetosphere are carried out. Using the implicit PIC and hybrid simulations, Mercury's relatively small, but highly kinetic magnetosphere will be examined to determine how the self-consistent inclusion of electrons affects magnetic reconnection, particle transport and acceleration of plasma at Mercury. Also the spatial and energy profiles of precipitating magnetospheric ions and electrons onto Mercury's surface, which can strongly affect the regolith in terms of space weathering and particle outflow, will be examined with the PIC and hybrid codes. MESSENGER spacecraft observations are used both to initiate and validate the global kinetic simulations to achieve a deeper understanding of the role kinetic physics play in magnetospheric dynamics.

Fast 2D Fluid-Analytical Simulation of IEDs and Plasma Uniformity in Multi-frequency CCPs

NASA Astrophysics Data System (ADS)

Kawamura, E.; Lieberman, M. A.; Graves, D. B.

2014-10-01

A fast 2D axisymmetric fluid-analytical model using the finite elements tool COMSOL is interfaced with a 1D particle-in-cell (PIC) code to study ion energy distributions (IEDs) in multi-frequency argon capacitively coupled plasmas (CCPs). A bulk fluid plasma model which solves the time-dependent plasma fluid equations is coupled with an analytical sheath model which solves for the sheath parameters. The fluid-analytical results are used as input to a PIC simulation of the sheath region of the discharge to obtain the IEDs at the wafer electrode. Each fluid-analytical-PIC simulation on a moderate 2.2 GHz CPU workstation with 8 GB of memory took about 15-20 minutes. The 2D multi-frequency fluid-analytical model was compared to 1D PIC simulations of a symmetric parallel plate discharge, showing good agreement. Fluid-analytical simulations of a 2/60/162 MHz argon CCP with a typical asymmetric reactor geometry were also conducted. The low 2 MHz frequency controlled the sheath width and voltage while the higher frequencies controlled the plasma production. A standing wave was observable at the highest frequency of 162 MHz. Adding 2 MHz power to a 60 MHz discharge or 162 MHz to a dual frequency 2 MHz/60 MHz discharge enhanced the plasma uniformity. This work was supported by the Department of Energy Office of Fusion Energy Science Contract DE-SC000193, and in part by gifts from Lam Research Corporation and Micron Corporation.

OSiRIS: a distributed Ceph deployment using software defined networking for multi-institutional research

NASA Astrophysics Data System (ADS)

McKee, Shawn; Kissel, Ezra; Meekhof, Benjeman; Swany, Martin; Miller, Charles; Gregorowicz, Michael

2017-10-01

We report on the first year of the OSiRIS project (NSF Award #1541335, UM, IU, MSU and WSU) which is targeting the creation of a distributed Ceph storage infrastructure coupled together with software-defined networking to provide high-performance access for well-connected locations on any participating campus. The projects goal is to provide a single scalable, distributed storage infrastructure that allows researchers at each campus to read, write, manage and share data directly from their own computing locations. The NSF CC*DNI DIBBS program which funded OSiRIS is seeking solutions to the challenges of multi-institutional collaborations involving large amounts of data and we are exploring the creative use of Ceph and networking to address those challenges. While OSiRIS will eventually be serving a broad range of science domains, its first adopter will be the LHC ATLAS detector project via the ATLAS Great Lakes Tier-2 (AGLT2) jointly located at the University of Michigan and Michigan State University. Part of our presentation will cover how ATLAS is using the OSiRIS infrastructure and our experiences integrating our first user community. The presentation will also review the motivations for and goals of the project, the technical details of the OSiRIS infrastructure, the challenges in providing such an infrastructure, and the technical choices made to address those challenges. We will conclude with our plans for the remaining 4 years of the project and our vision for what we hope to deliver by the projects end.

Development of a fully implicit particle-in-cell scheme for gyrokinetic electromagnetic turbulence simulation in XGC1

NASA Astrophysics Data System (ADS)

Ku, Seung-Hoe; Hager, R.; Chang, C. S.; Chacon, L.; Chen, G.; EPSI Team

2016-10-01

The cancelation problem has been a long-standing issue for long wavelengths modes in electromagnetic gyrokinetic PIC simulations in toroidal geometry. As an attempt of resolving this issue, we implemented a fully implicit time integration scheme in the full-f, gyrokinetic PIC code XGC1. The new scheme - based on the implicit Vlasov-Darwin PIC algorithm by G. Chen and L. Chacon - can potentially resolve cancelation problem. The time advance for the field and the particle equations is space-time-centered, with particle sub-cycling. The resulting system of equations is solved by a Picard iteration solver with fixed-point accelerator. The algorithm is implemented in the parallel velocity formalism instead of the canonical parallel momentum formalism. XGC1 specializes in simulating the tokamak edge plasma with magnetic separatrix geometry. A fully implicit scheme could be a way to accurate and efficient gyrokinetic simulations. We will test if this numerical scheme overcomes the cancelation problem, and reproduces the dispersion relation of Alfven waves and tearing modes in cylindrical geometry. Funded by US DOE FES and ASCR, and computing resources provided by OLCF through ALCC.

The UPSF code: a metaprogramming-based high-performance automatically parallelized plasma simulation framework

NASA Astrophysics Data System (ADS)

Gao, Xiatian; Wang, Xiaogang; Jiang, Binhao

2017-10-01

UPSF (Universal Plasma Simulation Framework) is a new plasma simulation code designed for maximum flexibility by using edge-cutting techniques supported by C++17 standard. Through use of metaprogramming technique, UPSF provides arbitrary dimensional data structures and methods to support various kinds of plasma simulation models, like, Vlasov, particle in cell (PIC), fluid, Fokker-Planck, and their variants and hybrid methods. Through C++ metaprogramming technique, a single code can be used to arbitrary dimensional systems with no loss of performance. UPSF can also automatically parallelize the distributed data structure and accelerate matrix and tensor operations by BLAS. A three-dimensional particle in cell code is developed based on UPSF. Two test cases, Landau damping and Weibel instability for electrostatic and electromagnetic situation respectively, are presented to show the validation and performance of the UPSF code.

Optical property retrievals of subvisual cirrus clouds from OSIRIS limb-scatter measurements

NASA Astrophysics Data System (ADS)

Wiensz, J. T.; Degenstein, D. A.; Lloyd, N. D.; Bourassa, A. E.

2012-08-01

We present a technique for retrieving the optical properties of subvisual cirrus clouds detected by OSIRIS, a limb-viewing satellite instrument that measures scattered radiances from the UV to the near-IR. The measurement set is composed of a ratio of limb radiance profiles at two wavelengths that indicates the presence of cloud-scattering regions. Optical properties from an in-situ database are used to simulate scattering by cloud-particles. With appropriate configurations discussed in this paper, the SASKTRAN successive-orders of scatter radiative transfer model is able to simulate accurately the in-cloud radiances from OSIRIS. Configured in this way, the model is used with a multiplicative algebraic reconstruction technique (MART) to retrieve the cloud extinction profile for an assumed effective cloud particle size. The sensitivity of these retrievals to key auxiliary model parameters is shown, and it is demonstrated that the retrieved extinction profile models accurately the measured in-cloud radiances from OSIRIS. Since OSIRIS has an 11-yr record of subvisual cirrus cloud detections, the work described in this manuscript provides a very useful method for providing a long-term global record of the properties of these clouds.

OSIRIS-REx Asteroid Sample-Return Mission

NASA Astrophysics Data System (ADS)

DellaGiustina, D. N.; Lauretta, D. S.

2016-12-01

Launching in September 2016, the primary objective of the Origins, Spectral Interpretation, Resource Identification, and Security-Regolith Explorer (OSIRIS-REx) mission is to return a pristine sample of asteroid (101955) Bennu to Earth for sample analysis. Bennu is a carbonaceous primitive near-Earth object, and is expected to be rich in volatile and organic material leftover from the formation of the Solar System. OSIRIS-REx will return a minimum of 60 g of bulk surface material from this body using a novel "touch-and-go" sample acquisition mechanism. Analyses of these samples will provide unprecedented knowledge about presolar history, from the initial stages of planet formation to the origin of life. Before sample acquisition, OSIRIS-REx will perform global mapping of Bennu, detailing the asteroid's composition and texture, resolving surface features, revealing its geologic and dynamic history, and providing context for the returned samples. The mission will also document the sampling site in situ at sub-centimeter scales, as well as the asteroid sampling event. In addition, OSIRIS-REx will measure the Yarkovsky effect, a non-Keplerian force affecting the orbit of this potentially hazardous asteroid, and provide a ground truth data for the interpretation of telescopic observations of carbonaceous asteroids.

Electron cyclotron thruster new modeling results preparation for initial experiments

NASA Technical Reports Server (NTRS)

Hooper, E. Bickford

1993-01-01

The following topics are discussed: a whistler-based electron cyclotron resonance heating (ECRH) thruster; cross-field coupling in the helicon approximation; wave propagation; wave structure; plasma density; wave absorption; the electron distribution function; isothermal and adiabatic plasma flow; ECRH thruster modeling; a PIC code model; electron temperature; electron energy; and initial experimental tests. The discussion is presented in vugraph form.

OSIRIS-REx Solar Array Illumination Test

NASA Image and Video Library

2016-08-05

Inside the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center in Florida, illumination testing is underway on the power-producing solar arrays for the agency’s Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer, or OSIRIS-REx spacecraft. Targeted for liftoff Sept. 8, 2016, OSIRIS-Rex will be the first U.S. mission to sample an asteroid, retrieve at least two ounces of surface material and return it to Earth for study. The asteroid, Bennu, may hold clues to the origin of the solar system and the source of water and organic molecules found on Earth.

OSIRIS-REx Solar Array Illumination Test

NASA Image and Video Library

2016-08-05

Inside the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center in Florida, illumination testing is underway on the power -producing solar arrays for the agency’s Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer, or OSIRIS-REx spacecraft. Targeted for liftoff Sept. 8, 2016, OSIRIS-Rex will be the first U.S. mission to sample an asteroid, retrieve at least two ounces of surface material and return it to Earth for study. The asteroid, Bennu, may hold clues to the origin of the solar system and the source of water and organic molecules found on Earth.

Comparison between layers stacks of 67P/CG comet and spectrophotometric variability obtained from OSIRIS data

NASA Astrophysics Data System (ADS)

Ferrari, S.; Penasa, L.; La Forgia, F.; Massironi, M.; Naletto, G.; Lazzarin, M.; Fornasier, S.; Barucci, M. A.; Lucchetti, A.; Pajola, M.; Frattin, E.; Bertini, I.; Ferri, F.; Cremonese, G.

2017-09-01

The Rosetta/OSIRIS cameras unveiled the layered nature of comet 67P/Churyumov-Gerasimenko, suggesting that the comet bilobate shape results from the low-velocity merging of two independent onion-like objects. Several physiographical regions of the southern-hemisphere big lobe show stacks of layers forming high scarps, terraces and mesas. A spectrophotometric analysis of OSIRIS images based on multispectral data classifications was conducted in order to identify possible morphological, textural and/or compositional characters that allow to distinguish regional stacks of layers.

Study of negative hydrogen ion beam optics using the 3D3V PIC model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miyamoto, K., E-mail: kmiyamot@naruto-u.ac.jp; Nishioka, S.; Goto, I.

The mechanism of negative ion extraction under real conditions with the complex magnetic field is studied by using the 3D PIC simulation code. The extraction region of the negative ion source for the negative ion based neutral beam injection system in fusion reactors is modelled. It is shown that the E x B drift of electrons is caused by the magnetic filter and the electron suppression magnetic field, and the resultant asymmetry of the plasma meniscus. Furthermore, it is indicated that that the asymmetry of the plasma meniscus results in the asymmetry of negative ion beam profile including the beammore » halo. It could be demonstrated theoretically that the E x B drift is not significantly weakened by the elastic collisions of the electrons with neutral particles.« less

Osiris9a is a major component of silk fiber in lepidopteran insects.

PubMed

Liu, Chun; Hu, Wenbo; Cheng, Tingcai; Peng, Zhangchuan; Mita, Kazuei; Xia, Qingyou

2017-10-01

In a previous high-throughput proteomics study, it was found that the silkworm cocoon contains hundreds of complex proteins, many of which have unknown functions, in addition to fibroins, sericins, and some protease inhibitors. Osiris was one of the proteins with no known function. In this study, we identified the Osiris gene family members and constructed a phylogenetic tree based on the sequences from different species. Our results indicate that the Osiris9 gene subfamily contains six members; it is specifically expressed in lepidopteran insects and has evolved by gene duplication. An Osiris gene family member from Bombyx mori was designated as BmOsiris9a (BmOsi9a) on the basis of its homology to Drosophila melanogaster Osiris9. The expression pattern of BmOsi9a showed that it was highly expressed only in the middle silk gland of silkworm larvae, similar to Sericin1 (Ser1). BmOsi9a was visualized as two bands in western blot analysis, implying that it probably undergoes post-translational modifications. Immunohistochemistry analysis revealed that BmOsi9a was synthesized and secreted into the lumen of the middle silk gland, and was localized in the sericin layer in the silk fiber. BmOsi9a was found in the silk fibers of not only three Bombycidae species, viz. B. mori, B. mandarina, and B. huttoni, but also in the fibers collected from Saturniidae species, including Antheraea assama, Antheraea mylitta, and Samia cynthia. Although the exact biological function of Osi9a in the silk fibers is unknown, our results are important because they demonstrate that Osi9a is a common structural component of silk fiber and is expressed widely among the silk-producing Bombycidae and Saturniidae insects. Our results should help in understanding the role of Osi9a in silk fibers. Copyright © 2017 Elsevier Ltd. All rights reserved.

Communicating Science on YouTube and Beyond: OSIRIS-REx Presents 321Science!

NASA Astrophysics Data System (ADS)

Spitz, Anna H.; Dykhuis, Melissa; Platts, Symeon; Keane, James T.; Tanquary, Hannah E.; Zellem, Robert; Hawley, Tiffany; Lauretta, Dante; Beshore, Ed; Bottke, Bill; Hergenrother, Carl; Dworkin, Jason P.; Patchell, Rose; Spitz, Sarah E.; Bentley, Zoe

2014-11-01

NASA’s OSIRIS-REx asteroid sample return mission launched OSIRIS-REx Presents 321Science!, a series of short videos, in December 2013 at youtube.com/osirisrex. A multi-disciplinary team of communicators, film and graphic arts students, teens, scientists, and engineers produces one video per month on a science and engineering topic related to the OSIRIS-REx mission. The format is designed to engage all members of the public, but especially younger audiences with the science and engineering of the mission. The videos serve as a resource for team members and others, complementing more traditional formats such as formal video interviews, mission animations, and hands-on activities. In creating this new form of OSIRIS-REx engagement, we developed 321Science! as an umbrella program to encourage expansion of the concept and topics beyond the OSIRIS-REx mission through partnerships. Such an expansion strengthens and magnifies the reach of the OSIRIS-REx efforts.321Science! has a detailed proposed schedule of video production through launch in 2016. Production plans are categorized to coincide with the course of the mission beginning with Learning the basics - about asteroids and the mission - and proceeding to Building the spacecraft, Run up to launch, Cruising to Bennu, Run up to rendezvous, Mapping Bennu, Sampling, Analyzing data, Cruising home and Returning and analyzing the sample. The video library will host a combination of videos on broad science topics and short specialized concepts with an average length of 2-3 minutes. Video production also takes into account external events, such as other missions’ milestones, to draw attention to our videos. Production will remain flexible and responsive to audience interests and needs and to developments in the mission, science, and external events. As of August 2014, 321Science! videos have over 22,000 views. We use YouTube analytics to evaluate our success and we are investigating additional and more rigorous evaluation methods for future analysis.

OSIRIS-REx Contamination Control Strategy and Implementation

NASA Technical Reports Server (NTRS)

Dworkin, J. P.; Adelman, L. A.; Ajluni, T.; Andronikov, A. V.; Aponte, J. C.; Bartels, A. E.; Beshore, E.; Bierhaus, E. B.; Brucato, J. R.; Bryan, B. H.;

OSIRIS-REx Contamination Control Strategy and Implementation

NASA Astrophysics Data System (ADS)

Dworkin, J. P.; Adelman, L. A.; Ajluni, T.; Andronikov, A. V.; Aponte, J. C.; Bartels, A. E.; Beshore, E.; Bierhaus, E. B.; Brucato, J. R.; Bryan, B. H.; Burton, A. S.; Callahan, M. P.; Castro-Wallace, S. L.; Clark, B. C.; Clemett, S. J.; Connolly, H. C.; Cutlip, W. E.; Daly, S. M.; Elliott, V. E.; Elsila, J. E.; Enos, H. L.; Everett, D. F.; Franchi, I. A.; Glavin, D. P.; Graham, H. V.; Hendershot, J. E.; Harris, J. W.; Hill, S. L.; Hildebrand, A. R.; Jayne, G. O.; Jenkens, R. W.; Johnson, K. S.; Kirsch, J. S.; Lauretta, D. S.; Lewis, A. S.; Loiacono, J. J.; Lorentson, C. C.; Marshall, J. R.; Martin, M. G.; Matthias, L. L.; McLain, H. L.; Messenger, S. R.; Mink, R. G.; Moore, J. L.; Nakamura-Messenger, K.; Nuth, J. A.; Owens, C. V.; Parish, C. L.; Perkins, B. D.; Pryzby, M. S.; Reigle, C. A.; Righter, K.; Rizk, B.; Russell, J. F.; Sandford, S. A.; Schepis, J. P.; Songer, J.; Sovinski, M. F.; Stahl, S. E.; Thomas-Keprta, K.; Vellinga, J. M.; Walker, M. S.

2018-02-01

OSIRIS-REx will return pristine samples of carbonaceous asteroid Bennu. This article describes how pristine was defined based on expectations of Bennu and on a realistic understanding of what is achievable with a constrained schedule and budget, and how that definition flowed to requirements and implementation. To return a pristine sample, the OSIRIS-REx spacecraft sampling hardware was maintained at level 100 A/2 and <180 ng/cm2 of amino acids and hydrazine on the sampler head through precision cleaning, control of materials, and vigilance. Contamination is further characterized via witness material exposed to the spacecraft assembly and testing environment as well as in space. This characterization provided knowledge of the expected background and will be used in conjunction with archived spacecraft components for comparison with the samples when they are delivered to Earth for analysis. Most of all, the cleanliness of the OSIRIS-REx spacecraft was achieved through communication among scientists, engineers, managers, and technicians.

OSIRIS-REx Contamination Control Strategy and Implementation

NASA Technical Reports Server (NTRS)

Dworkin, J. P.; Adelman, L. A.; Ajluni, T. M.; Andronikov, A. V.; Aponte, J. S.; Bartels, A. E.; Beshore, E.; Bierhaus, E. B.; Brucato, J. R.; Bryan, B. H.;

Spectral Characterization of Analog Samples in Anticipation of OSIRIS-REx's Arrival at Bennu

NASA Technical Reports Server (NTRS)

Donaldson Hanna, K. L.; Schrader, D. L.; Bowles, N. E.; Clark, B. E.; Cloutis, E. A.; Connolly, H. C., Jr.; Hamilton, V. E.; Keller, L. P.; Lauretta, D. S.; Lim, L. F.;

Making limb and nadir measurements comparable: A common volume study of PMC brightness observed by Odin OSIRIS and AIM CIPS

NASA Astrophysics Data System (ADS)

Benze, Susanne; Gumbel, Jörg; Randall, Cora E.; Karlsson, Bodil; Hultgren, Kristoffer; Lumpe, Jerry D.; Baumgarten, Gerd

2018-01-01

Combining limb and nadir satellite observations of Polar Mesospheric Clouds (PMCs) has long been recognized as problematic due to differences in observation geometry, scattering conditions, and retrieval approaches. This study offers a method of comparing PMC brightness observations from the nadir-viewing Aeronomy of Ice in the Mesosphere (AIM) Cloud Imaging and Particle Size (CIPS) instrument and the limb-viewing Odin Optical Spectrograph and InfraRed Imaging System (OSIRIS). OSIRIS and CIPS measurements are made comparable by defining a common volume for overlapping OSIRIS and CIPS observations for two northern hemisphere (NH) PMC seasons: NH08 and NH09. We define a scattering intensity quantity that is suitable for either nadir or limb observations and for different scattering conditions. A known CIPS bias is applied, differences in instrument sensitivity are analyzed and taken into account, and effects of cloud inhomogeneity and common volume definition on the comparison are discussed. Not accounting for instrument sensitivity differences or inhomogeneities in the PMC field, the mean relative difference in cloud brightness (CIPS - OSIRIS) is -102 ± 55%. The differences are largest for coincidences with very inhomogeneous clouds that are dominated by pixels that CIPS reports as non-cloud points. Removing these coincidences, the mean relative difference in cloud brightness reduces to -6 ± 14%. The correlation coefficient between the CIPS and OSIRIS measurements of PMC brightness variations in space and time is remarkably high, at 0.94. Overall, the comparison shows excellent agreement despite different retrieval approaches and observation geometries.

Investigations into the behaviour of Plasma surrounding Pulsars: DYMPHNA3D

NASA Astrophysics Data System (ADS)

Rochford, Ronan; Mc Donald, John; Shearer, Andy

2011-08-01

We report on a new 3D fully relativistic, modular, parallel and scalable Particle-In-Cell (PIC) code currently being developed at the Computational Astrophysics Laboratory in the National University of Ireland, Galway and its initial test applications to the plasma distribution in the vicinity of a rapidly rotating neutron star. We find that Plasma remains confined by trapping surfaces close to the star as opposed to propagating to a significant portion of the light-cylinder distance as predicted in this early work. We discuss planned future modifications and applications of the developed code.

Molecular architecture of the human Mediator-RNA polymerase II-TFIIF assembly.

PubMed

Bernecky, Carrie; Grob, Patricia; Ebmeier, Christopher C; Nogales, Eva; Taatjes, Dylan J

2011-03-01

The macromolecular assembly required to initiate transcription of protein-coding genes, known as the Pre-Initiation Complex (PIC), consists of multiple protein complexes and is approximately 3.5 MDa in size. At the heart of this assembly is the Mediator complex, which helps regulate PIC activity and interacts with the RNA polymerase II (pol II) enzyme. The structure of the human Mediator-pol II interface is not well-characterized, whereas attempts to structurally define the Mediator-pol II interaction in yeast have relied on incomplete assemblies of Mediator and/or pol II and have yielded inconsistent interpretations. We have assembled the complete, 1.9 MDa human Mediator-pol II-TFIIF complex from purified components and have characterized its structural organization using cryo-electron microscopy and single-particle reconstruction techniques. The orientation of pol II within this assembly was determined by crystal structure docking and further validated with projection matching experiments, allowing the structural organization of the entire human PIC to be envisioned. Significantly, pol II orientation within the Mediator-pol II-TFIIF assembly can be reconciled with past studies that determined the location of other PIC components relative to pol II itself. Pol II surfaces required for interacting with TFIIB, TFIIE, and promoter DNA (i.e., the pol II cleft) are exposed within the Mediator-pol II-TFIIF structure; RNA exit is unhindered along the RPB4/7 subunits; upstream and downstream DNA is accessible for binding additional factors; and no major structural re-organization is necessary to accommodate the large, multi-subunit TFIIH or TFIID complexes. The data also reveal how pol II binding excludes Mediator-CDK8 subcomplex interactions and provide a structural basis for Mediator-dependent control of PIC assembly and function. Finally, parallel structural analysis of Mediator-pol II complexes lacking TFIIF reveal that TFIIF plays a key role in stabilizing pol II orientation within the assembly.

Molecular Architecture of the Human Mediator–RNA Polymerase II–TFIIF Assembly

PubMed Central

Bernecky, Carrie; Grob, Patricia; Ebmeier, Christopher C.; Nogales, Eva; Taatjes, Dylan J.

2011-01-01

The macromolecular assembly required to initiate transcription of protein-coding genes, known as the Pre-Initiation Complex (PIC), consists of multiple protein complexes and is approximately 3.5 MDa in size. At the heart of this assembly is the Mediator complex, which helps regulate PIC activity and interacts with the RNA polymerase II (pol II) enzyme. The structure of the human Mediator–pol II interface is not well-characterized, whereas attempts to structurally define the Mediator–pol II interaction in yeast have relied on incomplete assemblies of Mediator and/or pol II and have yielded inconsistent interpretations. We have assembled the complete, 1.9 MDa human Mediator–pol II–TFIIF complex from purified components and have characterized its structural organization using cryo-electron microscopy and single-particle reconstruction techniques. The orientation of pol II within this assembly was determined by crystal structure docking and further validated with projection matching experiments, allowing the structural organization of the entire human PIC to be envisioned. Significantly, pol II orientation within the Mediator–pol II–TFIIF assembly can be reconciled with past studies that determined the location of other PIC components relative to pol II itself. Pol II surfaces required for interacting with TFIIB, TFIIE, and promoter DNA (i.e., the pol II cleft) are exposed within the Mediator–pol II–TFIIF structure; RNA exit is unhindered along the RPB4/7 subunits; upstream and downstream DNA is accessible for binding additional factors; and no major structural re-organization is necessary to accommodate the large, multi-subunit TFIIH or TFIID complexes. The data also reveal how pol II binding excludes Mediator–CDK8 subcomplex interactions and provide a structural basis for Mediator-dependent control of PIC assembly and function. Finally, parallel structural analysis of Mediator–pol II complexes lacking TFIIF reveal that TFIIF plays a key role in stabilizing pol II orientation within the assembly. PMID:21468301

Study on the After Cavity Interaction in a 140 GHz Gyrotron Using 3D CFDTD PIC Simulations

NASA Astrophysics Data System (ADS)

Lin, M. C.; Illy, S.; Avramidis, K.; Thumm, M.; Jelonnek, J.

2016-10-01

A computational study on after cavity interaction (ACI) in a 140 GHz gryotron for fusion research has been performed using a 3-D conformal finite-difference time-domain (CFDTD) particle-in-cell (PIC) method. The ACI, i.e. beam wave interaction in the non-linear uptaper after the cavity has attracted a lot of attention and been widely investigated in recent years. In a dynamic ACI, a TE mode is excited by the electron beam at the same frequency as in the cavity, and the same mode is also interacting with the spent electron beam at a different frequency in the non-linear uptaper after the cavity while in a static ACI, a mode interacts with the beam both at the cavity and at the uptaper, but at the same frequency. A previous study on the dynamic ACI on a 140 GHz gyrotron has concluded that more advanced numerical simulations such as particle-in-cell (PIC) modeling should be employed to study or confirm the dynamic ACI in addition to using trajectory codes. In this work, we use a 3-D full wave time domain simulation based on the CFDTD PIC method to include the rippled-wall launcher of the quasi-optical output coupler into the simulations which breaks the axial symmetry of the original model employing a symmetric one. A preliminary simulation result has confirmed the dynamic ACI effect in this 140 GHz gyrotron in good agreement with the former study. A realistic launcher will be included in the model for studying the dynamic ACI and compared with the homogenous one.

Analysis and optimization of chlorocarbon incineration through use of a detailed reaction mechanism

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ho, W.; Booty, M.R.; Magee, R.S.

1995-12-01

Chemical species profiles are calculated by using a detailed reaction mechanism and a reactor code that simulates a well-mixed, three-zone incineration process. The chemical systems include CH{sub 3}Cl/CH{sub 4} and CH{sub 2}Cl{sub 2}/CH{sub 4} oxidation in air at fuel equivalence ratios {phi} from 0.8 to 1.1, with additives injected at downstream positions. Combustion is characterized for temperature, principal organic hazardous constituent (POHC), and product of incomplete combustion (PIC) levels. Major PICs comprise Cl, CL{sub 2}, CO, HOCl, and COCl{sub 2} and are calculated versus time, temperature, fuel equivalence ratio, and feed conditions. Steam, H{sub 2}O{sub 2}, O{sub 2}, air, andmore » other species are injected as additives in the burnout region to discern changes i the combustion chemistry. Steam addition improves or decreases the CO/CO{sub 2} ratio at an additive mole fraction of 0.1. Atomic Cl is the active radical species of highest concentration in the initial high-temperature reaction zone when CH{sub 3}Cl is the POHC at a feed concentration above 1,200 ppm and {phi} {le} 1. Cl{sub 2} is found to be a major PIC under fuel-lean and stoichiometric conditions, while CO is a major PIC under fuel-rich conditions. Reduction of combined CO and Cl{sub 2} levels in the incinerator stack effluent is achieved by operation at stoichiometric conditions or slightly fuel-lean with the controlled addition of high-temperature steam.« less

Spectral Characterization of Analog Samples in Anticipation of OSIRIS-REx's Arrival at Bennu

NASA Technical Reports Server (NTRS)

Donaldson Hanna, K. L.; Schrader, D. L.; Bowles, N. E.; Clark, B. E.; Cloutis, E. A.; Connolly, H. C., Jr.; Hamilton, V. E.; Keller, L. P.; Lauretta, D. S.; Lim, L. F.;

KSC-20160908-RV-ANG01_0001-OSIRIS_REx_Launch_Broadcast_UCS_3_ISO-3126827

NASA Image and Video Library

2016-09-08

Liftoff of OSIRIS-A United Launch Alliance Atlas V rocket lifts off from Space Launch Complex 41 at Cape Canaveral Air Force Station carrying NASA’s Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer, or OSIRIS-REx spacecraft on the first U.S. mission to sample an asteroid, retrieve at least two ounces of surface material and return it to Earth for study. Liftoff was at 7:05 p.m. EDT. The asteroid, Bennu, may hold clues to the origin of the solar system and the source of water and organic molecules found on Earth.

KSC-20160908-RV-GEB01_0001-OSIRIS_REx_Launch_Broadcast_Van_1_People_Cutaways_ISO-3126827

NASA Image and Video Library

2016-09-08

Liftoff of OSIRIS-A United Launch Alliance Atlas V rocket lifts off from Space Launch Complex 41 at Cape Canaveral Air Force Station carrying NASA’s Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer, or OSIRIS-REx spacecraft on the first U.S. mission to sample an asteroid, retrieve at least two ounces of surface material and return it to Earth for study. Liftoff was at 7:05 p.m. EDT. The asteroid, Bennu, may hold clues to the origin of the solar system and the source of water and organic molecules found on Earth.

KSC-20160908-RV-CSH01_0001-OSIRIS_REx_Launch_Broadcast_Van_2_NASA_Causeway_ISO-3126827

NASA Image and Video Library

2016-09-08

Liftoff of OSIRIS-A United Launch Alliance Atlas V rocket lifts off from Space Launch Complex 41 at Cape Canaveral Air Force Station carrying NASA’s Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer, or OSIRIS-REx spacecraft on the first U.S. mission to sample an asteroid, retrieve at least two ounces of surface material and return it to Earth for study. Liftoff was at 7:05 p.m. EDT. The asteroid, Bennu, may hold clues to the origin of the solar system and the source of water and organic molecules found on Earth.

KSC-20160908-RV-GMM01_0003-OSIRIS_REx_Launch_Broadcast_Ground_ISO-3126827

NASA Image and Video Library

2016-09-08

Liftoff of OSIRIS-A United Launch Alliance Atlas V rocket lifts off from Space Launch Complex 41 at Cape Canaveral Air Force Station carrying NASA’s Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer, or OSIRIS-REx spacecraft on the first U.S. mission to sample an asteroid, retrieve at least two ounces of surface material and return it to Earth for study. Liftoff was at 7:05 p.m. EDT. The asteroid, Bennu, may hold clues to the origin of the solar system and the source of water and organic molecules found on Earth.

KSC-20160908-RV-GMM01_0002-OSIRIS_REx_Launch_Broadcast_VIF_ISO-3126827

NASA Image and Video Library

2016-09-08

Liftoff of OSIRIS-A United Launch Alliance Atlas V rocket lifts off from Space Launch Complex 41 at Cape Canaveral Air Force Station carrying NASA’s Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer, or OSIRIS-REx spacecraft on the first U.S. mission to sample an asteroid, retrieve at least two ounces of surface material and return it to Earth for study. Liftoff was at 7:05 p.m. EDT. The asteroid, Bennu, may hold clues to the origin of the solar system and the source of water and organic molecules found on Earth.

KSC-20160908-RV-GMM01_0001-OSIRIS_REx_Launch_Broadcast_VAB_Roof_ISO-3126827

NASA Image and Video Library

2016-09-08

Liftoff of OSIRIS-A United Launch Alliance Atlas V rocket lifts off from Space Launch Complex 41 at Cape Canaveral Air Force Station carrying NASA’s Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer, or OSIRIS-REx spacecraft on the first U.S. mission to sample an asteroid, retrieve at least two ounces of surface material and return it to Earth for study. Liftoff was at 7:05 p.m. EDT. The asteroid, Bennu, may hold clues to the origin of the solar system and the source of water and organic molecules found on Earth.

KSC-20160908-RV-ULA01_0001-OSIRIS_REx_Launch_Broadcast_Rocket_Cam_Ascent_ISO-3126827

NASA Image and Video Library

2016-09-08

Liftoff of OSIRIS-A United Launch Alliance Atlas V rocket lifts off from Space Launch Complex 41 at Cape Canaveral Air Force Station carrying NASA’s Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer, or OSIRIS-REx spacecraft on the first U.S. mission to sample an asteroid, retrieve at least two ounces of surface material and return it to Earth for study. Liftoff was at 7:05 p.m. EDT. The asteroid, Bennu, may hold clues to the origin of the solar system and the source of water and organic molecules found on Earth.

Numerical Design of Megawatt Gyrotron with 120 GHz Frequency and 50% Efficiency for Plasma Fusion Application

NASA Astrophysics Data System (ADS)

Kumar, Nitin; Singh, Udaybir; Kumar, Anil; Bhattacharya, Ranajoy; Singh, T. P.; Sinha, A. K.

2013-02-01

The design of 120 GHz, 1 MW gyrotron for plasma fusion application is presented in this paper. The mode selection is carried out considering the aim of minimum mode competition, minimum cavity wall heating, etc. On the basis of the selected operating mode, the interaction cavity design and beam-wave interaction computation are carried out by using the PIC code. The design of triode type Magnetron Injection Gun (MIG) is also presented. Trajectory code EGUN, synthesis code MIGSYN and data analysis code MIGANS are used in the MIG designing. Further, the design of MIG is also validated by using the another trajectory code TRAK. The design results of beam dumping system (collector) and RF window are also presented. Depressed collector is designed to enhance the overall tube efficiency. The design study confirms >1 MW output power with tube efficiency around 50% (with collector efficiency).

Scientific assessment of the quality of OSIRIS images

NASA Astrophysics Data System (ADS)

Tubiana, C.; Güttler, C.; Kovacs, G.; Bertini, I.; Bodewits, D.; Fornasier, S.; Lara, L.; La Forgia, F.; Magrin, S.; Pajola, M.; Sierks, H.; Barbieri, C.; Lamy, P. L.; Rodrigo, R.; Koschny, D.; Rickman, H.; Keller, H. U.; Agarwal, J.; A'Hearn, M. F.; Barucci, M. A.; Bertaux, J.-L.; Besse, S.; Boudreault, S.; Cremonese, G.; Da Deppo, V.; Davidsson, B.; Debei, S.; De Cecco, M.; El-Maarry, M. R.; Fulle, M.; Groussin, O.; Gutiérrez-Marques, P.; Gutiérrez, P. J.; Hoekzema, N.; Hofmann, M.; Hviid, S. F.; Ip, W.-H.; Jorda, L.; Knollenberg, J.; Kramm, J.-R.; Kührt, E.; Küppers, M.; Lazzarin, M.; Lopez Moreno, J. J.; Marzari, F.; Massironi, M.; Michalik, H.; Moissl, R.; Naletto, G.; Oklay, N.; Scholten, F.; Shi, X.; Thomas, N.; Vincent, J.-B.

2015-11-01

Context. OSIRIS, the scientific imaging system onboard the ESA Rosetta spacecraft, has been imaging the nucleus of comet 67P/Churyumov-Gerasimenko and its dust and gas environment since March 2014. The images serve different scientific goals, from morphology and composition studies of the nucleus surface, to the motion and trajectories of dust grains, the general structure of the dust coma, the morphology and intensity of jets, gas distribution, mass loss, and dust and gas production rates. Aims: We present the calibration of the raw images taken by OSIRIS and address the accuracy that we can expect in our scientific results based on the accuracy of the calibration steps that we have performed. Methods: We describe the pipeline that has been developed to automatically calibrate the OSIRIS images. Through a series of steps, radiometrically calibrated and distortion corrected images are produced and can be used for scientific studies. Calibration campaigns were run on the ground before launch and throughout the years in flight to determine the parameters that are used to calibrate the images and to verify their evolution with time. We describe how these parameters were determined and we address their accuracy. Results: We provide a guideline to the level of trust that can be put into the various studies performed with OSIRIS images, based on the accuracy of the image calibration.

OsiriX software as a preoperative planning tool in cranial neurosurgery: A step-by-step guide for neurosurgical residents

PubMed Central

Spiriev, Toma; Nakov, Vladimir; Laleva, Lili; Tzekov, Christo

2017-01-01

Background: OsiriX (Pixmeo, Switzerland) is an open-source Digital Imaging and Communications in Medicine (DICOM) viewer that is gaining more and more attention in the neurosurgical community because of its user-friendly interface, powerful three-dimensional (3D) volumetric rendering capabilities, and various options for data integration. This paper presents in detail the use of OsiriX software as a preoperative planning tool in cranial neurosurgery. Methods: In January 2013, OsiriX software was introduced into our clinical practice as a preoperative planning tool. Its capabilities are being evaluated on an ongoing basis in routine elective cranial cases. Results: The program has proven to be highly effective at volumetrically representing data from radiological examinations in 3D. Among its benefits in preoperative planning are simulating the position and exact location of the lesion in 3D, tailoring the skin incision and craniotomy bone flap, enhancing the representation of normal and pathological anatomy, and aiding in planning the reconstruction of the affected area. Conclusion: OsiriX is a useful tool for preoperative planning and visualization in neurosurgery. The software greatly facilitates the surgeon's understanding of the relationship between normal and pathological anatomy and can be used as a teaching tool. PMID:29119039

Massive collisions in debris disks: possible application to the beta Pic disc

NASA Astrophysics Data System (ADS)

Kral, Q.; Thébault, P.; Augereau, J.-C.; Boccaletti, A.; Charnoz, S.

2014-09-01

The new LIDT-DD code has been used to study massive collisions in debris discs. This new hybrid model is a fully self-consistent code coupling dynamics and collisions to study debris discs (Kral et al. 2013). It models the full complexity of debris discs' physics such as high velocity collisions, radiation-pressure affected orbits, wide range of grains' dynamical behaviour, etc. LIDT-DD can be used on many possible applications. Our first test case concerns the violent breakup of a massive planetesimal such as the ones happening during the late stages of planetary formation or with the biggest bodies in debris belts. We investigate the duration, magnitude and spatial structure of the signature left by such a violent event, as well as its observational detectability. We find that the breakup of a Ceres-sized body creates an asymmetric dust disc that is homogenized, by the coupled action of collisions and dynamics. The luminosity excess in the breakup's aftermath should be detectable by mid-IR photometry, from a 30 pc distance. As for the asymmetric structures, we derive synthetic images for the SPHERE/VLT and MIRI/JWST instruments, showing that they should be clearly visible and resolved from a 10 pc distance. We explain the observational signature of such impacts and give scaling laws to extrapolate our results to different configurations. These first results confirm that our code can be used to study the massive collision scenario to explain some asymmetries in the Beta-Pic disc.

An Architecture for Real-Time Processing of OSIRIS-REx Engineering and Science Data, from Raw Telemetry to PDS

NASA Astrophysics Data System (ADS)

Selznick, S. H.

2017-06-01

Herein we describe an architecture developed for processing engineering and science data for the OSIRIS-REx mission. The architecture is soup-to-nuts, starting with raw telemetry and ending with submission to PDS.

Correction: Spectroscopic characteristics of the OSIRIS near-backscattering crystal analyser spectrometer on the ISIS pulsed neutron source.

PubMed

Telling, Mark T F; Campbell, Stuart I; Engberg, Dennis; Martín Y Marero, David; Andersen, Ken H

2016-03-21

Correction for 'Spectroscopic characteristics of the OSIRIS near-backscattering crystal analyser spectrometer on the ISIS pulsed neutron source' by Mark T. F. Telling et al., Phys. Chem. Chem. Phys., 2005, 7, 1255-1261.

Controlling Laser Plasma Instabilities Using Temporal Bandwidth

NASA Astrophysics Data System (ADS)

Tsung, Frank; Weaver, J.; Lehmberg, R.

2016-10-01

We are performing particle-in-cell simulations using the code OSIRIS to study the effects of laser plasma interactions in the presence of temporal bandwidth under conditions relevant to current and future experiments on the NIKE laser. Our simulations show that, for sufficiently large bandwidth (where the inverse bandwidth is comparable with the linear growth time), the saturation level, and the distribution of hot electrons, can be effected by the addition of temporal bandwidths (which can be accomplished in experiments using beam smoothing techniques such as ISI). We will quantify these effects and investigate higher dimensional effects such as laser speckles. This work is supported by DOE and NRL.

OSIRIS-REx Asteroid Sample Return Mission Image Analysis

NASA Astrophysics Data System (ADS)

Chevres Fernandez, Lee Roger; Bos, Brent

2018-01-01

NASA’s Origins Spectral Interpretation Resource Identification Security-Regolith Explorer (OSIRIS-REx) mission constitutes the “first-of-its-kind” project to thoroughly characterize a near-Earth asteroid. The selected asteroid is (101955) 1999 RQ36 (a.k.a. Bennu). The mission launched in September 2016, and the spacecraft will reach its asteroid target in 2018 and return a sample to Earth in 2023. The spacecraft that will travel to, and collect a sample from, Bennu has five integrated instruments from national and international partners. NASA's OSIRIS-REx asteroid sample return mission spacecraft includes the Touch-And-Go Camera System (TAGCAMS) three camera-head instrument. The purpose of TAGCAMS is to provide imagery during the mission to facilitate navigation to the target asteroid, confirm acquisition of the asteroid sample and document asteroid sample stowage. Two of the TAGCAMS cameras, NavCam 1 and NavCam 2, serve as fully redundant navigation cameras to support optical navigation and natural feature tracking. The third TAGCAMS camera, StowCam, provides imagery to assist with and confirm proper stowage of the asteroid sample. Analysis of spacecraft imagery acquired by the TAGCAMS during cruise to the target asteroid Bennu was performed using custom codes developed in MATLAB. Assessment of the TAGCAMS in-flight performance using flight imagery was done to characterize camera performance. One specific area of investigation that was targeted was bad pixel mapping. A recent phase of the mission, known as the Earth Gravity Assist (EGA) maneuver, provided images that were used for the detection and confirmation of “questionable” pixels, possibly under responsive, using image segmentation analysis. Ongoing work on point spread function morphology and camera linearity and responsivity will also be used for calibration purposes and further analysis in preparation for proximity operations around Bennu. Said analyses will provide a broader understanding regarding the functionality of the camera system, which will in turn aid in the fly-down to the asteroid, as it will allow the pick of a suitable landing and sample location.

Effects of Radiation Damping in Extreme Ultra-intense Laser-Plasma Interaction

NASA Astrophysics Data System (ADS)

Pandit, Rishi R.

Recent advances in the development of intense short pulse lasers are significant. Now it is available to access a laser with intensity 1021W/cm2 by focusing a petawatt class laser. In a few years, the intensity will exceed 1022W/cm2 , at which intensity electrons accelerated by the laser get energy more than 100 MeV and start to emit radiation strongly. Resultingly, the damping of electron motion can become large. In order to study this problem, we developed a code to solve a set of equations describing the evolution of a strong electromagnetic wave interacting with a single electron. Usually the equation of motion of an electron including radiation damping under the influence of electromagnetic fields is derived from the Lorentz-Dirac equation treating the damping as a perturbation. So far people had used the first order damping equation. This is because the second order term seems to be small and actually it is negligible under 1022W/cm2 intensity. The derivation of 2nd order equation is also complicated and challenging. We derived the second order damping equations for the first time and implemented in the code. The code was then tested via single particle motion in the extreme intensity laser. It was found that the 1st order damping term is reasonable up to the intensity 1022W/cm2, but the 2nd oder term becomes not negligible and comparable in magnitude to the first order term beyond 1023W/cm2. The radiation damping model was introduced using a one-dimensional particle-in-cell code (PIC), and tested in the laser-plasma interaction at extreme intensity. The strong damping of hot electrons in high energy tail was demonstrated in PIC simulations.

Automating OSIRIS Data Reduction for the Keck Observatory Archive

NASA Astrophysics Data System (ADS)

Holt, J.; Tran, H. D.; Goodrich, R.; Berriman, G. B.; Gelino, C. R.; KOA Team

2014-05-01

By the end of 2013, the Keck Observatory Archive (KOA) will serve data from all active instruments on the Keck Telescopes. OSIRIS (OH-Suppressing Infra-Red Imaging Spectrograph), the last active instrument to be archived in KOA, has been in use behind the (AO) system at Keck since February 2005. It uses an array of tiny lenslets to simultaneously produce spectra at up to 4096 locations. Due to the complicated nature of the OSIRIS raw data, the OSIRIS team developed a comprehensive data reduction program. This data reduction system has an online mode for quick real-time reductions, which are used primarily for basic data visualization and quality assessment done at the telescope while observing. The offline version of the data reduction system includes an expanded reduction method list, does more iterations for a better construction of the data cubes, and is used to produce publication-quality products. It can also use reconstruction matrices that are developed after the observations were taken, and are more refined. The KOA team is currently utilizing the standard offline reduction mode to produce quick-look browse products for the raw data. Users of the offline data reduction system generally use a graphical user interface to manually setup the reduction parameters. However, in order to reduce and serve the 200,000 science files on disk, all of the reduction parameters and steps need to be fully automated. This pipeline will also be used to automatically produce quick-look browse products for future OSIRIS data after each night's observations. Here we discuss the complexities of OSIRIS data, the reduction system in place, methods for automating the system, performance using virtualization, and progress made to date in generating the KOA products.

Automating OSIRIS Data Reduction for the Keck Observatory Archive

NASA Astrophysics Data System (ADS)

Tran, Hien D.; Holt, J.; Goodrich, R. W.; Lyke, J. E.; Gelino, C. R.; Berriman, G. B.; KOA Team

2014-01-01

Since the end of 2013, the Keck Observatory Archive (KOA) has served data from all active instruments on the Keck Telescopes. OSIRIS (OH-Suppressing Infra-Red Imaging Spectrograph), the last active instrument to be archived in KOA, has been in use behind the adaptive optics (AO) system at Keck since February 2005. It uses an array of tiny lenslets to simultaneously produce spectra at up to 4096 locations. Due to the complicated nature of the OSIRIS raw data, the OSIRIS team developed a comprehensive data reduction program. This data reduction system has an online mode for quick real-time reductions which are used primarily for basic data visualization and quality assessment done at the telescope while observing. The offline version of the data reduction system includes an expanded reduction method list, does more iterations for a better construction of the data cubes, and is used to produce publication-quality products. It can also use reconstruction matrices that are developed after the observations were taken, and are more refined. The KOA team is currently utilizing the standard offline reduction mode to produce quick-look browse products for the raw data. Users of the offline data reduction system generally use a graphical user interface to manually setup the reduction parameters. However, in order to reduce and serve the ~200,000 science files on disk, all of the reduction parameters and steps need to be fully automated. This pipeline will also be used to automatically produce quick-look browse products for future OSIRIS data after each night's observations. Here we discuss the complexities of OSIRIS data, the reduction system in place, methods for automating the system, performance using virtualization, and progress made to date in generating the KOA products.

Comparative assessment of a real-time particle monitor against the reference gravimetric method for PM10 and PM2.5 in indoor air

NASA Astrophysics Data System (ADS)

Tasić, Viša; Jovašević-Stojanović, Milena; Vardoulakis, Sotiris; Milošević, Novica; Kovačević, Renata; Petrović, Jelena

2012-07-01

Accurate monitoring of indoor mass concentrations of particulate matter is very important for health risk assessment as people in developed countries spend approximately 90% of their time indoors. The direct reading, aerosol monitoring device, Turnkey, OSIRIS Particle Monitor (Model 2315) and the European reference low volume sampler, LVS3 (Sven/Leckel LVS3) with size-selective inlets for PM10 and PM2.5 fractions were used to assess the comparability of available optical and gravimetric methods for particulate matter characterization in indoor air. Simultaneous 24-hour samples were collected in an indoor environment for 60 sampling periods in the town of Bor, Serbia. The 24-hour mean PM10 levels from the OSIRIS monitor were well correlated with the LVS3 levels (R2 = 0.87) and did not show statistically significant bias. The 24-hour mean PM2.5 levels from the OSIRIS monitor were moderately correlated with the LVS3 levels (R2 = 0.71), but show statistically significant bias. The results suggest that the OSIRIS monitor provides sufficiently accurate measurements for PM10. The OSIRIS monitor underestimated the indoor PM10 concentrations by approximately 12%, relative to the reference LVS3 sampler. The accuracy of PM10 measurements could be further improved through empirical adjustment. For the fine fraction of particulate matter, PM2.5, it was found that the OSIRIS monitor underestimated indoor concentrations by approximately 63%, relative to the reference LVS3 sampler. This could lead to exposure misclassification in health effects studies relying on PM2.5 measurements collected with this instrument in indoor environments.

Electrostatic plasma simulation by Particle-In-Cell method using ANACONDA package

NASA Astrophysics Data System (ADS)

Blandón, J. S.; Grisales, J. P.; Riascos, H.

2017-06-01

Electrostatic plasma is the most representative and basic case in plasma physics field. One of its main characteristics is its ideal behavior, since it is assumed be in thermal equilibrium state. Through this assumption, it is possible to study various complex phenomena such as plasma oscillations, waves, instabilities or damping. Likewise, computational simulation of this specific plasma is the first step to analyze physics mechanisms on plasmas, which are not at equilibrium state, and hence plasma is not ideal. Particle-In-Cell (PIC) method is widely used because of its precision for this kind of cases. This work, presents PIC method implementation to simulate electrostatic plasma by Python, using ANACONDA packages. The code has been corroborated comparing previous theoretical results for three specific phenomena in cold plasmas: oscillations, Two-Stream instability (TSI) and Landau Damping(LD). Finally, parameters and results are discussed.

Paradigms and strategies for scientific computing on distributed memory concurrent computers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Foster, I.T.; Walker, D.W.

1994-06-01

In this work we examine recent advances in parallel languages and abstractions that have the potential for improving the programmability and maintainability of large-scale, parallel, scientific applications running on high performance architectures and networks. This paper focuses on Fortran M, a set of extensions to Fortran 77 that supports the modular design of message-passing programs. We describe the Fortran M implementation of a particle-in-cell (PIC) plasma simulation application, and discuss issues in the optimization of the code. The use of two other methodologies for parallelizing the PIC application are considered. The first is based on the shared object abstraction asmore » embodied in the Orca language. The second approach is the Split-C language. In Fortran M, Orca, and Split-C the ability of the programmer to control the granularity of communication is important is designing an efficient implementation.« less

Theoretical analysis and Vsim simulation of a low-voltage high-efficiency 250 GHz gyrotron

NASA Astrophysics Data System (ADS)

An, Chenxiang; Zhang, Dian; Zhang, Jun; Zhong, Huihuang

2018-02-01

Low-voltage, high-frequency gyrotrons with hundreds of watts of power are useful in radar, magnetic resonance spectroscopy and plasma diagnostic applications. In this paper, a 10 kV, 478 W, 250 GHz gyrotron with an efficiency of nearly 40% and a pitch ratio of 1.5 was designed through linear and nonlinear numerical analyses and Vsim particle-in-cell (PIC) simulation. Vsim is a highly efficient parallel PIC code, but it has seldom been used to carry out electron beam wave interaction simulations of gyro-devices. The setting up of the parameters required for the Vsim simulations of the gyrotron is presented. The results of Vsim simulations agree well with that of nonlinear numerical calculation. The commercial software Vsim7.2 completed the 3D gyrotron simulation in 80 h using a 20 core, 2.2 GHz personal computer with 256 GBytes of memory.

Three dimensional particle-in-cell simulations of electron beams created via reflection of intense laser light from a water target

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ngirmang, Gregory K., E-mail: ngirmang.1@osu.edu; Orban, Chris; Feister, Scott

We present 3D Particle-in-Cell (PIC) modeling of an ultra-intense laser experiment by the Extreme Light group at the Air Force Research Laboratory using the Large Scale Plasma (LSP) PIC code. This is the first time PIC simulations have been performed in 3D for this experiment which involves an ultra-intense, short-pulse (30 fs) laser interacting with a water jet target at normal incidence. The laser-energy-to-ejected-electron-energy conversion efficiency observed in 2D(3v) simulations were comparable to the conversion efficiencies seen in the 3D simulations, but the angular distribution of ejected electrons in the 2D(3v) simulations displayed interesting differences with the 3D simulations' angular distribution;more » the observed differences between the 2D(3v) and 3D simulations were more noticeable for the simulations with higher intensity laser pulses. An analytic plane-wave model is discussed which provides some explanation for the angular distribution and energies of ejected electrons in the 2D(3v) simulations. We also performed a 3D simulation with circularly polarized light and found a significantly higher conversion efficiency and peak electron energy, which is promising for future experiments.« less

Introducing a distributed unstructured mesh into gyrokinetic particle-in-cell code, XGC

NASA Astrophysics Data System (ADS)

Yoon, Eisung; Shephard, Mark; Seol, E. Seegyoung; Kalyanaraman, Kaushik

2017-10-01

XGC has shown good scalability for large leadership supercomputers. The current production version uses a copy of the entire unstructured finite element mesh on every MPI rank. Although an obvious scalability issue if the mesh sizes are to be dramatically increased, the current approach is also not optimal with respect to data locality of particles and mesh information. To address these issues we have initiated the development of a distributed mesh PIC method. This approach directly addresses the base scalability issue with respect to mesh size and, through the use of a mesh entity centric view of the particle mesh relationship, provides opportunities to address data locality needs of many core and GPU supported heterogeneous systems. The parallel mesh PIC capabilities are being built on the Parallel Unstructured Mesh Infrastructure (PUMI). The presentation will first overview the form of mesh distribution used and indicate the structures and functions used to support the mesh, the particles and their interaction. Attention will then focus on the node-level optimizations being carried out to ensure performant operation of all PIC operations on the distributed mesh. Partnership for Edge Physics Simulation (EPSI) Grant No. DE-SC0008449 and Center for Extended Magnetohydrodynamic Modeling (CEMM) Grant No. DE-SC0006618.

The OSIRIS-REx Visible and InfraRed Spectrometer (OVIRS): Spectral Maps of the Asteroid Bennu

NASA Astrophysics Data System (ADS)

Reuter, D. C.; Simon, A. A.; Hair, J.; Lunsford, A.; Manthripragada, S.; Bly, V.; Bos, B.; Brambora, C.; Caldwell, E.; Casto, G.; Dolch, Z.; Finneran, P.; Jennings, D.; Jhabvala, M.; Matson, E.; McLelland, M.; Roher, W.; Sullivan, T.; Weigle, E.; Wen, Y.; Wilson, D.; Lauretta, D. S.

2018-03-01

The OSIRIS-REx Visible and Infrared Spectrometer (OVIRS) is a point spectrometer covering the spectral range of 0.4 to 4.3 microns (25,000-2300 cm-1). Its primary purpose is to map the surface composition of the asteroid Bennu, the target asteroid of the OSIRIS-REx asteroid sample return mission. The information it returns will help guide the selection of the sample site. It will also provide global context for the sample and high spatial resolution spectra that can be related to spatially unresolved terrestrial observations of asteroids. It is a compact, low-mass (17.8 kg), power efficient (8.8 W average), and robust instrument with the sensitivity needed to detect a 5% spectral absorption feature on a very dark surface (3% reflectance) in the inner solar system (0.89-1.35 AU). It, in combination with the other instruments on the OSIRIS-REx Mission, will provide an unprecedented view of an asteroid's surface.

OSIRIS-REx Atlas V Wet Dress Rehearsal

NASA Image and Video Library

2016-08-25

The booster and Centaur upper stage of a United Launch Alliance Atlas V vent gaseous propellant during a “wet dress rehearsal” test at Space Launch Complex 41 on Florida’s Cape Canaveral Air Force Station. The rocket will boost NASA’s Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer, or OSIRIS-REx spacecraft. Targeted for liftoff Sept. 8, 2016, OSIRIS-REx will be the first U.S. mission to sample an asteroid, retrieve at least two ounces of surface material and return it to Earth for study. The asteroid, Bennu, may hold clues to the origin of the solar system and the source of water and organic molecules found on Earth.

OSIRIS-REx Launch Event at Goddard Visitor Center. NASA's first

NASA Image and Video Library

2016-09-08

OSIRIS-REx Launch Event at Goddard Visitor Center. NASA's first asteroid sampling mission launched into space at 7:05 p.m. EDT Thursday from Cape Canaveral Air Force Station in Florida, beginning a journey that could revolutionize our understanding of the early solar system.

Modelling short pulse, high intensity laser plasma interactions

NASA Astrophysics Data System (ADS)

Evans, R. G.

2006-06-01

Modelling the interaction of ultra-intense laser pulses with solid targets is made difficult through the large range of length and time scales involved in the transport of relativistic electrons. An implicit hybrid PIC-fluid model using the commercial code LSP (LSP is marketed by MRC (Albuquerque), New Mexico, USA) reveals a variety of complex phenomena which seem to be borne out in experiments and some existing theories.

Implementation of non-axisymmetric mesh system in the gyrokinetic PIC code (XGC) for Stellarators

NASA Astrophysics Data System (ADS)

Moritaka, Toseo; Hager, Robert; Cole, Micheal; Chang, Choong-Seock; Lazerson, Samuel; Ku, Seung-Hoe; Ishiguro, Seiji

2017-10-01

Gyrokinetic simulation is a powerful tool to investigate turbulent and neoclassical transports based on the first-principles of plasma kinetics. The gyrokinetic PIC code XGC has been developed for integrated simulations that cover the entire region of Tokamaks. Complicated field line and boundary structures should be taken into account to demonstrate edge plasma dynamics under the influence of X-point and vessel components. XGC employs gyrokinetic Poisson solver on unstructured triangle mesh to deal with this difficulty. We introduce numerical schemes newly developed for XGC simulation in non-axisymmetric Stellarator geometry. Triangle meshes in each poloidal plane are defined by PEST poloidal angle in the VMEC equilibrium so that they have the same regular structure in the straight field line coordinate. Electric charge of marker particle is distributed to the triangles specified by the field-following projection to the neighbor poloidal planes. 3D spline interpolation in a cylindrical mesh is also used to obtain equilibrium magnetic field at the particle position. These schemes capture the anisotropic plasma dynamics and resulting potential structure with high accuracy. The triangle meshes can smoothly connect to unstructured meshes in the edge region. We will present the validation test in the core region of Large Helical Device and discuss about future challenges toward edge simulations.

PIC simulations of the trapped electron filamentation instability in finite-width electron plasma waves

NASA Astrophysics Data System (ADS)

Winjum, B. J.; Banks, J. W.; Berger, R. L.; Cohen, B. I.; Chapman, T.; Hittinger, J. A. F.; Rozmus, W.; Strozzi, D. J.; Brunner, S.

2012-10-01

We present results on the kinetic filamentation of finite-width nonlinear electron plasma waves (EPW). Using 2D simulations with the PIC code BEPS, we excite a traveling EPW with a Gaussian transverse profile and a wavenumber k0λDe= 1/3. The transverse wavenumber spectrum broadens during transverse EPW localization for small width (but sufficiently large amplitude) waves, while the spectrum narrows to a dominant k as the initial EPW width increases to the plane-wave limit. For large EPW widths, filaments can grow and destroy the wave coherence before transverse localization destroys the wave; the filaments in turn evolve individually as self-focusing EPWs. Additionally, a transverse electric field develops that affects trapped electrons, and a beam-like distribution of untrapped electrons develops between filaments and on the sides of a localizing EPW. This work was performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344 and funded by the Laboratory Research and Development Program at LLNL under project tracking code 12-ERD-061. Supported also under Grants DE-FG52-09NA29552 and NSF-Phy-0904039. Simulations were performed on UCLA's Hoffman2 and NERSC's Hopper.

Computationally efficient description of relativistic electron beam transport in dense plasma

NASA Astrophysics Data System (ADS)

Polomarov, Oleg; Sefkov, Adam; Kaganovich, Igor; Shvets, Gennady

2006-10-01

A reduced model of the Weibel instability and electron beam transport in dense plasma is developed. Beam electrons are modeled by macro-particles and the background plasma is represented by electron fluid. Conservation of generalized vorticity and quasineutrality of the plasma-beam system are used to simplify the governing equations. Our approach is motivated by the conditions of the FI scenario, where the beam density is likely to be much smaller than the plasma density and the beam energy is likely to be very high. For this case the growth rate of the Weibel instability is small, making the modeling of it by conventional PICs exceedingly time consuming. The present approach does not require resolving the plasma period and only resolves a plasma collisionless skin depth and is suitable for modeling a long-time behavior of beam-plasma interaction. An efficient code based on this reduced description is developed and benchmarked against the LSP PIC code. The dynamics of low and high current electron beams in dense plasma is simulated. Special emphasis is on peculiarities of its non-linear stages, such as filament formation and merger, saturation and post-saturation field and energy oscillations. *Supported by DOE Fusion Science through grant DE-FG02-05ER54840.

BENNU’S JOURNEY - Early Earth

NASA Image and Video Library

2017-12-08

This is an artist's concept of the young Earth being bombarded by asteroids. Scientists think these impacts could have delivered significant amounts of organic matter and water to Earth. Image Credit: NASA's Goddard Space Flight Center Conceptual Image Lab The Origins Spectral Interpretation Resource Identification Security -- Regolith Explorer spacecraft (OSIRIS-REx) will travel to a near-Earth asteroid, called Bennu, and bring a sample back to Earth for study. The mission will help scientists investigate how planets formed and how life began, as well as improve our understanding of asteroids that could impact Earth. OSIRIS-REx is scheduled for launch in late 2016. As planned, the spacecraft will reach its asteroid target in 2018 and return a sample to Earth in 2023. Watch the full video: youtu.be/gtUgarROs08 Learn more about NASA’s OSIRIS-REx mission and the making of Bennu’s Journey: www.nasa.gov/content/goddard/bennus-journey/ More information on the OSIRIS-REx mission is available at: www.nasa.gov/mission_pages/osiris-rex/index.html www.asteroidmission.org NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

Spacecraft-environment interaction model cross comparison applied to Solar Probe Plus

NASA Astrophysics Data System (ADS)

Lapenta, G.; Deca, J.; Markidis, S.; Marchand, R.; Guillemant, S.; Matéo Vélez, J.; Miyake, Y.; Usui, H.; Ergun, R.; Sturner, A. P.

2013-12-01

Given that our society becomes increasingly dependent on space technology, it is imperative to develop a good understanding of spacecraft-plasma interactions. Two main issues are important. First, one needs to be able to design a reliable spacecraft that can survive in the harsh solar wind conditions, and second a very good knowledge of the behaviour and plasma structure around the spacecraft is required to be able to interpret and correct measurements from onboard instruments and science experiments. In this work we present the results of a cross-comparison study between five spacecraft-plasma models (EMSES, iPic3D, LASP, PTetra, SPIS) used to simulate the interaction of the Solar Probe Plus (SPP) satellite with the space environment under representative solar wind conditions near perihelion. The purpose of this cross-comparison is to assess the consistency and validity of the different numerical approaches from the similarities and differences of their predictions under well defined conditions, with attention to the implicit PIC code iPic3D, which has never been used for spacecraft-environment interaction studies before. The physical effects considered are spacecraft charging, photoelectron and secondary electron emission, the presence of a background magnetic field and density variations. The latter of which can cause the floating potential of SPP to go from negative to positive or visa versa, depending on the solar wind conditions, and spacecraft material properties. Simulation results are presented and compared with increasing levels of complexity in the physics to evaluate the sensitivity of the model predictions to certain physical effects. The comparisons focus particularly on spacecraft floating potential, detailed contributions to the currents collected and emitted by the spacecraft, and on the potential and density spatial profiles near the satellite. Model predictions obtained with our different computational approaches are found to be in good agreement when the physical processes are treated similarly. The comparisons considered here indicate that, with the correct parameterization of important physical effects such as photoemission and secondary electron emission, our simulation models should have the required skill to predict details of satellite-plasma interaction physics with a high level of confidence. This work was supported by the International Space Science Institute in Bern Switzerland. The potential profile around the Solar Probe Plus spacecraft in orbital flow, from the iPic3D code. The physical model includes photo- and secondary electrons and a static magnetic field.

OSIRIS-REx Launch Event at Goddard Visitor Center. NASA's first

NASA Image and Video Library

2016-09-08

OSIRIS-REx Launch Event at Goddard Visitor Center. NASA's first asteroid sampling mission launched into space at 7:05 p.m. EDT Thursday from Cape Canaveral Air Force Station in Florida beginning a journey that could revolutionize our understanding of the early solar system. Lucy McFadden

Fast 2D fluid-analytical simulation of ion energy distributions and electromagnetic effects in multi-frequency capacitive discharges

NASA Astrophysics Data System (ADS)

Kawamura, E.; Lieberman, M. A.; Graves, D. B.

2014-12-01

A fast 2D axisymmetric fluid-analytical plasma reactor model using the finite elements simulation tool COMSOL is interfaced with a 1D particle-in-cell (PIC) code to study ion energy distributions (IEDs) in multi-frequency capacitive argon discharges. A bulk fluid plasma model, which solves the time-dependent plasma fluid equations for the ion continuity and electron energy balance, is coupled with an analytical sheath model, which solves for the sheath parameters. The time-independent Helmholtz equation is used to solve for the fields and a gas flow model solves for the steady-state pressure, temperature and velocity of the neutrals. The results of the fluid-analytical model are used as inputs to a PIC simulation of the sheath region of the discharge to obtain the IEDs at the target electrode. Each 2D fluid-analytical-PIC simulation on a moderate 2.2 GHz CPU workstation with 8 GB of memory took about 15-20 min. The multi-frequency 2D fluid-analytical model was compared to 1D PIC simulations of a symmetric parallel-plate discharge, showing good agreement. We also conducted fluid-analytical simulations of a multi-frequency argon capacitively coupled plasma (CCP) with a typical asymmetric reactor geometry at 2/60/162 MHz. The low frequency 2 MHz power controlled the sheath width and sheath voltage while the high frequencies controlled the plasma production. A standing wave was observable at the highest frequency of 162 MHz. We noticed that adding 2 MHz power to a 60 MHz discharge or 162 MHz to a dual frequency 2 MHz/60 MHz discharge can enhance the plasma uniformity. We found that multiple frequencies were not only useful for controlling IEDs but also plasma uniformity in CCP reactors.

Recruitment and rate coding organisation for soleus motor units across entire range of voluntary isometric plantar flexions.

PubMed

Oya, Tomomichi; Riek, Stephan; Cresswell, Andrew G

2009-10-01

Unlike upper limb muscles, it remains undocumented as to how motor units in the soleus muscle are organised in terms of recruitment range and discharge rates with respect to their recruitment and de-recruitment thresholds. The possible influence of neuromodulation, such as persistent inward currents (PICs) on lower limb motor unit recruitment and discharge rates has also yet to be reported. To address these issues, electromyographic (EMG) activities from the soleus muscle were recorded using selective branched-wire intramuscular electrodes during ramp-and-hold contractions with intensities up to maximal voluntary contraction (MVC). The multiple single motor unit activities were then derived using a decomposition technique. The onset-offset hysteresis of motor unit discharge, i.e. a difference between recruitment and de-recruitment thresholds, as well as PIC magnitude calculated by a paired motor unit analysis were used to examine the neuromodulatory effects on discharge behaviours, such as minimum firing rate, peak firing rate and degree of increase in firing rate. Forty-two clearly identified motor units from five subjects revealed that soleus motor units are recruited progressively from rest to contraction strengths close to 95% of MVC, with low-threshold motor units discharging action potentials slower at their recruitment and with a lower peak rate than later recruited high-threshold units. This observation is in contrast to the 'onion skin phenomenon' often reported for the upper limb muscles. Based on positive correlations of the peak discharge rates, initial rates and recruitment order of the units with the magnitude of the onset-offset hysteresis and not PIC contribution, we conclude that discharge behaviours among motor units appear to be related to a variation in an intrinsic property other than PICs.

[Accession to the PIC/S and pharmaceutical quality system in Japan].

PubMed

Katori, Noriko

2014-01-01

In March, 2012, Japan made the application for membership of the Pharmaceutical Inspection convention and Pharmaceutical Inspection Co-operation scheme (PIC/S) which is an international body of a GMP inspection. The globalization of pharmaceutical manufacturing and sales has been a driving force behind the decision to become a PIC/S member. For the application for membership, Japan's GMP inspectorate needs to fulfill PIC/S requirements, for example, the inspection organization has to have a quality system as a global standard. One of the other requirements is that the GMP inspectorate can access Official Medicines Control Laboratories (OMCL) having high analytical skills and also have a quality system based on ISO 17025. I would like to describe the process to make up a quality system in the National Institute of Health Sciences and also the circumstances around the PIC/S application in Japan.

Hybrid model for simulation of plasma jet injection in tokamak

NASA Astrophysics Data System (ADS)

Galkin, Sergei A.; Bogatu, I. N.

2016-10-01

Hybrid kinetic model of plasma treats the ions as kinetic particles and the electrons as charge neutralizing massless fluid. The model is essentially applicable when most of the energy is concentrated in the ions rather than in the electrons, i.e. it is well suited for the high-density hyper-velocity C60 plasma jet. The hybrid model separates the slower ion time scale from the faster electron time scale, which becomes disregardable. That is why hybrid codes consistently outperform the traditional PIC codes in computational efficiency, still resolving kinetic ions effects. We discuss 2D hybrid model and code with exact energy conservation numerical algorithm and present some results of its application to simulation of C60 plasma jet penetration through tokamak-like magnetic barrier. We also examine the 3D model/code extension and its possible applications to tokamak and ionospheric plasmas. The work is supported in part by US DOE DE-SC0015776 Grant.

Object-oriented design of medical imaging software.

PubMed

Ligier, Y; Ratib, O; Logean, M; Girard, C; Perrier, R; Scherrer, J R

1994-01-01

A special software package for interactive display and manipulation of medical images was developed at the University Hospital of Geneva, as part of a hospital wide Picture Archiving and Communication System (PACS). This software package, called Osiris, was especially designed to be easily usable and adaptable to the needs of noncomputer-oriented physicians. The Osiris software has been developed to allow the visualization of medical images obtained from any imaging modality. It provides generic manipulation tools, processing tools, and analysis tools more specific to clinical applications. This software, based on an object-oriented paradigm, is portable and extensible. Osiris is available on two different operating systems: the Unix X-11/OSF-Motif based workstations, and the Macintosh family.

The Osiris-Rex Mission - Sample Acquisitions Strategy and Evidence for the Nature of Regolith on Asteroid (101955) 1999 RQ36

NASA Technical Reports Server (NTRS)

Lauretta, D. S.; Barucci, M. A.; Bierhaus, E. B.; Brucato, J. R.; Campins, H.; Christensen, P. R.; Clark, B. C.; Connolly, H. C.; Dotto, E.; Dworkin, J. P.;

A portable approach for PIC on emerging architectures

NASA Astrophysics Data System (ADS)

Decyk, Viktor

2016-03-01

A portable approach for designing Particle-in-Cell (PIC) algorithms on emerging exascale computers, is based on the recognition that 3 distinct programming paradigms are needed. They are: low level vector (SIMD) processing, middle level shared memory parallel programing, and high level distributed memory programming. In addition, there is a memory hierarchy associated with each level. Such algorithms can be initially developed using vectorizing compilers, OpenMP, and MPI. This is the approach recommended by Intel for the Phi processor. These algorithms can then be translated and possibly specialized to other programming models and languages, as needed. For example, the vector processing and shared memory programming might be done with CUDA instead of vectorizing compilers and OpenMP, but generally the algorithm itself is not greatly changed. The UCLA PICKSC web site at http://www.idre.ucla.edu/ contains example open source skeleton codes (mini-apps) illustrating each of these three programming models, individually and in combination. Fortran2003 now supports abstract data types, and design patterns can be used to support a variety of implementations within the same code base. Fortran2003 also supports interoperability with C so that implementations in C languages are also easy to use. Finally, main codes can be translated into dynamic environments such as Python, while still taking advantage of high performing compiled languages. Parallel languages are still evolving with interesting developments in co-Array Fortran, UPC, and OpenACC, among others, and these can also be supported within the same software architecture. Work supported by NSF and DOE Grants.

South Carolina Student Accountability System OSIRIS Instruction Manual.

ERIC Educational Resources Information Center

South Carolina State Dept. of Education, Columbia.

This manual expresses the South Carolina State Department of Education's understanding of the new, computerized school administration system called OSIRIS and the policy regarding its use with the Student Accountability System (SAS). The SAS is a method used to obtain a cumulative headcount of students served in certain programs specified in the…

OSIRIS-REx Launch Event at Goddard Visitor Center. NASA's first

NASA Image and Video Library

2016-09-08

OSIRIS-REx Launch Event at Goddard Visitor Center. NASA's first asteroid sampling mission launched into space at 7:05 p.m. EDT Thursday from Cape Canaveral Air Force Station in Florida beginning a journey that could revolutionize our understanding of the early solar system. Dr. Jim Glavin.Lucy McFadden.Dr. Jose Aponte

Precision estimate for Odin-OSIRIS limb scatter retrievals

NASA Astrophysics Data System (ADS)

Bourassa, A. E.; McLinden, C. A.; Bathgate, A. F.; Elash, B. J.; Degenstein, D. A.

2012-02-01

The limb scatter measurements made by the Optical Spectrograph and Infrared Imaging System (OSIRIS) instrument on the Odin spacecraft are used to routinely produce vertically resolved trace gas and aerosol extinction profiles. Version 5 of the ozone and stratospheric aerosol extinction retrievals, which are available for download, are performed using a multiplicative algebraic reconstruction technique (MART). The MART inversion is a type of relaxation method, and as such the covariance of the retrieved state is estimated numerically, which, if done directly, is a computationally heavy task. Here we provide a methodology for the derivation of a numerical estimate of the covariance matrix for the retrieved state using the MART inversion that is sufficiently efficient to perform for each OSIRIS measurement. The resulting precision is compared with the variability in a large set of pairs of OSIRIS measurements that are close in time and space in the tropical stratosphere where the natural atmospheric variability is weak. These results are found to be highly consistent and thus provide confidence in the numerical estimate of the precision in the retrieved profiles.

BENNU’S JOURNEY

NASA Image and Video Library

2017-12-08

Asteroid Bennu is a time capsule, containing the raw ingredients of the solar system. Bennu has settled in a near-Earth orbit. Today, a NASA spacecraft OSIRIS-REx is going to retrieve a sample to learn more about our Solar System’s history. OSIRIRS-REx is a NASA sample return mission to visit Asteroid Bennu. We plan to grab a piece of Bennu, because it’s a time capsule that can tell us about the origins of our planet and our entire solar system. Watch the full video: youtu.be/gtUgarROs08 Learn more about NASA’s OSIRIS-REx mission and the making of Bennu’s Journey: www.nasa.gov/content/goddard/bennus-journey/ More information on the OSIRIS-REx mission is available at: www.nasa.gov/mission_pages/osiris-rex/index.html www.asteroidmission.org NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

Modelling of the outburst on July 29th , 2015 observed with OSIRIS in the southern hemisphere of comet 67P/Churyumov-Gerasimenko

NASA Astrophysics Data System (ADS)

Gicquel, Adeline; Vincent, Jean-Baptiste; Sierks, Holger; Rose, Martin; Agarwal, Jessica; Deller, Jakob; Guettler, Carsten; Hoefner, Sebastian; Hofmann, Marc; Hu, Xuanyu; Kovacs, Gabor; Oklay Vincent, Nilda; Shi, Xian; Tubiana, Cecilia; Barbieri, Cesare; Lamy, Phylippe; Rodrigo, Rafael; Koschny, Detlef; Rickman, Hans; OSIRIS Team

2016-10-01

Images of the nucleus and the coma (gas and dust) of comet 67P/Churyumov- Gerasimenko have been acquired by the OSIRIS (Optical, Spectroscopic, and Infrared Remote Imaging System) cameras system since March 2014 using both the wide angle camera (WAC) and the narrow angle camera (NAC). We are using the NAC camera to study the bright outburst observed on July 29th, 2015 in the southern hemisphere. The NAC camera's wavelength ranges between 250-1000 nm with a combination of 12 filters. The high spatial resolution is needed to localize the source point of the outburst on the surface of the nucleus. At the time of the observations, the heliocentric distance was 1.25AU and the distance between the spacecraft and the comet was 126 km. We aim to understand the physics leading to such outgassing: Is the jet associated to the outbursts controlled by the micro-topography? Or by ice suddenly exposed? We are using the Direct Simulation Monte Carlo (DSMC) method to study the gas flow close to the nucleus. The goal of the DSMC code is to reproduce the opening angle of the jet, and constrain the outgassing ratio between outburst source and local region. The results of this model will be compared to the images obtained with the NAC camera.

Development of 1D Particle-in-Cell Code and Simulation of Plasma-Wall Interactions

NASA Astrophysics Data System (ADS)

Rose, Laura P.

This thesis discusses the development of a 1D particle-in-cell (PIC) code and the analysis of plasma-wall interactions. The 1D code (Plasma and Wall Simulation -- PAWS) is a kinetic simulation of plasma done by treating both electrons and ions as particles. The goal of this thesis is to study near wall plasma interaction to better understand the mechanism that occurs in this region. The main focus of this investigation is the effects that secondary electrons have on the sheath profile. The 1D code is modeled using the PIC method. Treating both the electrons and ions as macroparticles the field is solved on each node and weighted to each macro particle. A pre-ionized plasma was loaded into the domain and the velocities of particles were sampled from the Maxwellian distribution. An important part of this code is the boundary conditions at the wall. If a particle hits the wall a secondary electron may be produced based on the incident energy. To study the sheath profile the simulations were run for various cases. Varying background neutral gas densities were run with the 2D code and compared to experimental values. Different wall materials were simulated to show their effects of SEE. In addition different SEE yields were run, including one study with very high SEE yields to show the presence of a space charge limited sheath. Wall roughness was also studied with the 1D code using random angles of incidence. In addition to the 1D code, an external 2D code was also used to investigate wall roughness without secondary electrons. The roughness profiles where created upon investigation of wall roughness inside Hall Thrusters based off of studies done on lifetime erosion of the inner and outer walls of these devices. The 2D code, Starfish[33], is a general 2D axisymmetric/Cartesian code for modeling a wide a range of plasma and rarefied gas problems. These results show that higher SEE yield produces a smaller sheath profile and that wall roughness produces a lower SEE yield. Modeling near wall interactions is not a simple or perfected task. Due to the lack of a second dimension and a sputtering model it is not possible with this study to show the positive effects wall roughness could have on Hall thruster performance since roughness occurs from the negative affect of sputtering.

The implementation of multi-task geophysical survey to locate Cleopatra Tomb at Tap-Osiris Magna, Borg El-Arab, Alexandria, Egypt “Phase II”

NASA Astrophysics Data System (ADS)

Abbas, Abbas M.; Khalil, Mohamed A.; Massoud, Usama; Santos, Fernando M.; Mesbah, Hany A.; Lethy, Ahmed; Soliman, Mamdouh; Ragab, El Said A.

2012-06-01

According to some new discoveries at Tap-Osiris Magna temple (West of Alexandria), there is potentiality to uncover a remarkable archeological finding at this site. Three years ago many significant archeological evidences have been discovered sustaining the idea that the tomb of Cleopatra and Anthony may be found in the Osiris temple inside Tap-Osiris Magna temple at a depth from 20 to 30 m. To confirm this idea, PHASE I was conducted in by joint application of Ground Penetrating Radar “GPR”, Electrical Resistivity Tomography “ERT” and Magnetometry. The results obtained from PHASE I could not confirm the existence of major tombs at this site. However, small possible cavities were strongly indicated which encouraged us to proceed in investigation of this site by using another geophysical approach including Very Low Frequency Electro Magnetic (VLF-EM) technique. VLF-EM data were collected along parallel lines covering the investigated site with a line-to-line spacing of 1 m. The point-to-point distance of 1 m along the same line was employed. The data were qualitatively interpreted by Fraser filtering process and quantitatively by 2-D VLF inversion of tipper data and forward modeling. Results obtained from VLF-EM interpretation are correlated with 2-D resistivity imaging and drilling information. Findings showed a highly resistive zone at a depth extended from about 25-45 m buried beneath Osiris temple, which could be indicated as the tomb of Cleopatra and Anthony. This result is supported by Fraser filtering and forward modeling results. The depth of archeological findings as indicated from the geophysical survey is correlated well with the depth expected by archeologists, as well as, the depth of discovered tombs outside Tap-Osiris Magna temple. This depth level has not been reached by drilling in this site. We hope that the site can be excavated in the future based on these geophysical results.

OSIRIS-REx Asterod Sample Return Mission

NASA Technical Reports Server (NTRS)

Nakamura-Messinger, Keiki; Connolly, Harold C. Jr.; Messenger, Scott; Lauretta, Dante S.

2017-01-01

OSIRIS-REx is NASA's third New Frontiers Program mission, following New Horizons that completed a flyby of Pluto in 2015 and the Juno mission to Jupiter that has just begun science operations. The OSIRIS-REx mission's primary objective is to collect pristine surface samples of a carbonaceous asteroid and return to Earth for analysis. Carbonaceous asteroids and comets are 'primitive' bodies that preserved remnants of the Solar System starting materials and through their study scientists can learn about the origin and the earliest evolution of the Solar System. The OSIRIS-REx spacecraft was successfully launched on September 8, 2016, beginning its seven year journey to asteroid 101955 Bennu. The robotic arm will collect 60-2000 grams of material from the surface of Bennu and will return to Earth in 2023 for worldwide distribution by the Astromaterials Curation Facility at NASA Johnson Space Center. The name OSIRIS-REx embodies the mission objectives (1) Origins: Return and analyze a sample of a carbonaceous asteroid, (2) Spectral Interpretation: Provide ground-truth for remote observation of asteroids, (3) Resource Identification: Determine the mineral and chemical makeup of a near-Earth asteroid (4) Security: Measure the non-gravitational that changes asteroidal orbits and (5) Regolith Explorer: Determine the properties of the material covering an asteroid surface. Asteroid Bennu may preserve remnants of stardust, interstellar materials and the first solids to form in the Solar System and the molecular precursors to the origin of life and the Earth's oceans. Bennu is a potentially hazardous asteroid, with an approximately 1 in 2700 chance of impacting the Earth late in the 22nd century. OSIRIS-REx collects from Bennu will help formulate the types of operations and identify mission activities that astronauts will perform during their expeditions. Such information is crucial in preparing for humanity's next steps beyond low Earthy orbit and on to deep space destinations.

Constructing a short form of the hierarchical personality inventory for children (HiPIC): the HiPIC-30.

PubMed

Vollrath, Margarete E; Hampson, Sarah E; Torgersen, Svenn

2016-05-01

Children's personality traits are invaluable predictors of concurrent and later mental and physical health. Several validated longer inventories for assessing the widely recognized Five-Factor Model of personality in children are available, but short forms are scarce. This study aimed at constructing a 30-item form of the 144-item Hierarchical Personality Inventory for Children (HiPIC) (Mervielde & De Fruyt, ). Participants were 1543 children aged 6-12 years (sample 1) and 3895 children aged 8 years (sample 2). Sample 1 completed the full HiPIC, from which we constructed the HiPIC-30, and the Child Behaviour Checklist (Achenbach, ). Sample 2 completed the HiPIC-30. The HiPIC-30 personality domains correlated over r = .90 with the full HiPIC domains, had good Cronbach's alphas and correlated similarly with CBCL behaviour problems and gender as the full HiPIC. The factor structures of the HiPIC-30 were convergent across samples, but the imagination factor was not clear-cut. We conclude that the HiPIC-30 is a reliable and valid questionnaire for the Five-Factor personality traits in children. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

Particle-in-cell simulations of collisionless shock formation via head-on merging of two laboratory supersonic plasma jets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thoma, C.; Welch, D. R.; Hsu, S. C.

2013-08-15

We describe numerical simulations, using the particle-in-cell (PIC) and hybrid-PIC code lsp[T. P. Hughes et al., Phys. Rev. ST Accel. Beams 2, 110401 (1999)], of the head-on merging of two laboratory supersonic plasma jets. The goals of these experiments are to form and study astrophysically relevant collisionless shocks in the laboratory. Using the plasma jet initial conditions (density ∼10{sup 14}–10{sup 16} cm{sup −3}, temperature ∼ few eV, and propagation speed ∼20–150 km/s), large-scale simulations of jet propagation demonstrate that interactions between the two jets are essentially collisionless at the merge region. In highly resolved one- and two-dimensional simulations, we showmore » that collisionless shocks are generated by the merging jets when immersed in applied magnetic fields (B∼0.1–1 T). At expected plasma jet speeds of up to 150 km/s, our simulations do not give rise to unmagnetized collisionless shocks, which require much higher velocities. The orientation of the magnetic field and the axial and transverse density gradients of the jets have a strong effect on the nature of the interaction. We compare some of our simulation results with those of previously published PIC simulation studies of collisionless shock formation.« less

VizieR Online Data Catalog: QSO eHAQ0111+0641 spectra (Fynbo+, 2017)

NASA Astrophysics Data System (ADS)

Fynbo, J. P. U.; Krogager, J.-K.; Heintz, K. E.; Geier, S.; Moller, P.; Noterdaeme, P.; Christensen, L.; Ledoux, C.; Jakobsson, P.

2017-09-01

eHAQ0111+0641 was observed with the OSIRIS instrument at the Gran Telescopio Canarias (GTC) as part of a larger sample of candidate red quasars. We secured spectroscopy with OSIRIS and a range of grisms to better constrain the spectral energy distribution, metal lines, and hydrogen Lyα line. (2 data files).

OSIRIS-REx Touch-And-Go (TAG) Mission Design and Analysis

NASA Technical Reports Server (NTRS)

Berry, Kevin; Sutter, Brian; May, Alex; Williams, Ken; Barbee, Brent W.; Beckman, Mark; Williams, Bobby

2013-01-01

The Origins Spectral Interpretation Resource Identification Security Regolith Explorer (OSIRIS-REx) mission is a NASA New Frontiers mission launching in 2016 to rendezvous with the near-Earth asteroid (101955) 1999 RQ36 in late 2018. After several months in formation with and orbit about the asteroid, OSIRIS-REx will fly a Touch-And-Go (TAG) trajectory to the asteroid s surface to obtain a regolith sample. This paper describes the mission design of the TAG sequence and the propulsive maneuvers required to achieve the trajectory. This paper also shows preliminary results of orbit covariance analysis and Monte-Carlo analysis that demonstrate the ability to arrive at a targeted location on the surface of RQ36 within a 25 meter radius with 98.3% confidence.

Rosetta/OSIRIS - Nucleus morphology and activity of comet 67P/Churyumov-Gerasimenko

NASA Astrophysics Data System (ADS)

Sierks, Holger; Barbieri, Cesare; Lamy, Philippe; Rickman, Hans; Rodrigo, Rafael; Koschny, Detlef

2015-04-01

ESA's Rosetta mission arrived on August 6, 2014, at target comet 67P/Churyumov-Gerasimenko after 10 years of cruise. OSIRIS (Optical, Spectroscopic, and Infrared Remote Imaging System) is the scientific imaging system onboard Rosetta. It comprises a Narrow Angle Camera (NAC) for nucleus surface and dust studies and a Wide Angle Camera (WAC) for the wide field coma investigations. OSIRIS imaged the nucleus and coma of the comet from the arrival throughout the mapping phase, PHILAE landing, early escort phase and close fly-by. The overview paper will discuss the surface morpholo-gy and activity of the nucleus as seen in gas, dust, and local jets as well as small scale structures in the local topography.

General Mission Analysis Tool (GMAT)

NASA Technical Reports Server (NTRS)

Hughes, Steven P. (Compiler)

2016-01-01

This is a software tutorial and presentation demonstrating the application of the General Mission Analysis Tool (GMAT) to the critical design phase of NASA missions. The demonstration discusses GMAT basics, then presents a detailed example of GMAT application to the Transiting Exoplanet Survey Satellite (TESS) mission. Other examples include OSIRIS-Rex. This talk is a combination of existing presentations; a GMAT basics and overview, and technical presentations from the TESS and OSIRIS-REx projects on their application of GMAT to critical mission design. The GMAT basics slides are taken from the open source training material. The OSIRIS-REx slides are from a previous conference presentation. The TESS slides are a streamlined version of the CDR package provided by the project with SBU and ITAR data removed by the TESS project.

Chromium picolinate modulates serotonergic properties and carbohydrate metabolism in a rat model of diabetes.

PubMed

Komorowski, James R; Tuzcu, Mehmet; Sahin, Nurhan; Juturu, Vijaya; Orhan, Cemal; Ulas, Mustafa; Sahin, Kazim

2012-10-01

Chromium picolinate (CrPic) has shown both antidepressant and antidiabetic properties. In this study, the effects of CrPic on serotonergic properties and carbohydrate metabolism in diabetic rats were evaluated. Sixty male Sprague-Dawley rats were divided into four groups. (1) The control group received only standard diet (8 % fat). (2) The CrPic group was fed standard diet and CrPic (80 μg CrPic per kilogram body mass (b.m.)/day), for 10 weeks (microgram/kilogram b.m./day). (3) The HFD/STZ group fed a high-fat diet (HFD, 40 % fat) for 2 weeks and then received streptozotocin (STZ, 40 mg/kg, i.p.) (i.v.) HFD-STZ-CrPic group treated as the previous group and then were administered CrPic. CrPic administration to HFD/STZ-treated rats increased brain chromium levels and improved all measurements of carbohydrate metabolism and serotonergic properties (P<0.001). CrPic also significantly increased levels of insulin, tryptophan, and serotonin (P<0.001) in the serum and brain, and decreased cortisol levels in the serum (P<0.01). Except chromium levels, no significant effect of CrPic supplementation was detected on the overall measured parameters in the control group. CrPic administration was well tolerated without any adverse events. The results support the use of CrPic supplementation which improves serotonergic properties of brain in diabetes.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Romanov, Gennady

Typically the RFQs are designed using the Parmteq, DesRFQ and other similar specialized codes, which produces the files containing the field and geometrical parameters for every cell. The beam dynamic simulations with these analytical fields a re, of course, ideal realizations of the designed RFQs. The new advanced computing capabilities made it possible to simulate beam and even dark current in the realistic 3D electromagnetic fields in the RFQs that may reflect cavity tuning, presence of tune rs and couplers, RFQ segmentation etc. The paper describes the utilization of full 3D field distribution obtained with CST Studio Suite for beammore » dynamic simulations using both PIC solver of CST Particle Studio and the beam dynamic code TRACK.« less

A two-dimensional particle-in-cell model of a dusty plasma

NASA Technical Reports Server (NTRS)

Young, B.; Cravens, T. E.; Armstrong, T. P.; Friauf, R. J.

1994-01-01

Dusty plasmas are present in comets, in the ring systems of the outer planets, and in the interstellar medium. A two-dimensional particle-in-cell (PIC) model of a dusty plasma is presented in this paper. The PIC code is best suited for modeling the plasma-dust interaction for large grains, with diameters of the order of a centimeter. We have modeled the charging process for an individual dust grain and the associated potential pattern in the surrounding plasma. We have also considered the case of a large number of grains in a plasma, with intergrain separations of the order of the Debye length, and have shown that the plasma becomes depleted and the charge on a dust grain is reduced, as other workers in this field have predicted (cf. C. K. Goertz, 1989). We examine the electron and ion distribution functions in the vicinity of a charged grain and demonstrate that the ions near a grain have clearly been accelerated by the electrostatic potential.

Particle distributions in collisionless magnetic reconnection: An implicit Particle-In-Cell (PIC) description

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hewett, D.W.; Francis, G.E.; Max, C.E.

1990-06-29

Evidence from magnetospheric and solar flare research supports the belief that collisionless magnetic reconnection can proceed on the Alfven-wave crossing timescale. Reconnection behavior that occurs this rapidly in collisionless plasmas is not well understood because underlying mechanisms depend on the details of the ion and electron distributions in the vicinity of the emerging X-points. We use the direct implicit Particle-In-Cell (PIC) code AVANTI to study the details of these distributions as they evolve in the self-consistent E and B fields of magnetic reconnection. We first consider a simple neutral sheet model. We observe rapid movement of the current-carrying electrons awaymore » from the emerging X-point. Later in time an oscillation of the trapped magnetic flux is found, superimposed upon continued linear growth due to plasma inflow at the ion sound speed. The addition of a current-aligned and a normal B field widen the scope of our studies.« less

Genome-wide uniformity of human ‘open’ pre-initiation complexes

PubMed Central

Lai, William K.M.; Pugh, B. Franklin

2017-01-01

Transcription of protein-coding and noncoding DNA occurs pervasively throughout the mammalian genome. Their sites of initiation are generally inferred from transcript 5′ ends and are thought to be either locally dispersed or focused. How these two modes of initiation relate is unclear. Here, we apply permanganate treatment and chromatin immunoprecipitation (PIP-seq) of initiation factors to identify the precise location of melted DNA separately associated with the preinitiation complex (PIC) and the adjacent paused complex (PC). This approach revealed the two known modes of transcription initiation. However, in contrast to prevailing views, they co-occurred within the same promoter region: initiation originating from a focused PIC, and broad nucleosome-linked initiation. PIP-seq allowed transcriptional orientation of Pol II to be determined, which may be useful near promoters where sufficient sense/anti-sense transcript mapping information is lacking. PIP-seq detected divergently oriented Pol II at both coding and noncoding promoters, as well as at enhancers. Their occupancy levels were not necessarily coupled in the two orientations. DNA sequence and shape analysis of initiation complex sites suggest that both sequence and shape contribute to specificity, but in a context-restricted manner. That is, initiation sites have the locally “best” initiator (INR) sequence and/or shape. These findings reveal a common core to pervasive Pol II initiation throughout the human genome. PMID:27927716

Influence of the normal modes on the plasma uniformity in large scale CCP reactors

NASA Astrophysics Data System (ADS)

Eremin, Denis; Brinkmann, Ralf Peter; Mussenbrock, Thomas; Lane, Barton; Matsukuma, Masaaki; Ventzek, Peter

2016-09-01

Large scale capacitively coupled plasmas (CCP) driven by sources with high frequency components often exhibit phenomena which are absent in relatively well understood small scale CCPs driven at low frequencies. Of particular interest are such phenomena which affect discharge parameters of direct relevance to the plasma processing applications. One of such parameters is plasma uniformity. By using a self-consistent 2d3v Particle-in-cell/Monte-Carlo (PIC/MCC) code parallelized on GPU we have been able to show that uniformity of the plasma generated is influenced predominantly by two factors, the ionization pattern caused by high-energy electrons and the average temperature of low-energy plasma electrons. The heating mechanisms for these two groups of electrons appear to be different leading to different transversal (radial) profiles of the corresponding factors, which is well captured by the kinetic PIC/MCC code. We find that the heating mechanisms are intrinsically connected with excitation of normal modes inherent to a plasma-filled CCP reactor. In this work we study the wave nature of these phenomena, such as their excitation, propagation, and interaction with electrons. Supported by SFB-TR 87 project of the German Research Foundation and by the ``Experimental and numerical analysis of very high frequency capacitively coupled plasma discharges'' mutual research project between RUB and Tokyo Electron Ltd.

Comparisons of 'Identical' Simulations by the Eulerian Gyrokinetic Codes GS2 and GYRO

NASA Astrophysics Data System (ADS)

Bravenec, R. V.; Ross, D. W.; Candy, J.; Dorland, W.; McKee, G. R.

2003-10-01

A major goal of the fusion program is to be able to predict tokamak transport from first-principles theory. To this end, the Eulerian gyrokinetic code GS2 was developed years ago and continues to be improved [1]. Recently, the Eulerian code GYRO was developed [2]. These codes are not subject to the statistical noise inherent to particle-in-cell (PIC) codes, and have been very successful in treating electromagnetic fluctuations. GS2 is fully spectral in the radial coordinate while GYRO uses finite-differences and ``banded" spectral schemes. To gain confidence in nonlinear simulations of experiment with these codes, ``apples-to-apples" comparisons (identical profile inputs, flux-tube geometry, two species, etc.) are first performed. We report on a series of linear and nonlinear comparisons (with overall agreement) including kinetic electrons, collisions, and shaped flux surfaces. We also compare nonlinear simulations of a DIII-D discharge to measurements of not only the fluxes but also the turbulence parameters. [1] F. Jenko, et al., Phys. Plasmas 7, 1904 (2000) and refs. therein. [2] J. Candy, J. Comput. Phys. 186, 545 (2003).

Molecular analysis of hprt mutations induced by chromium picolinate in CHO AA8 cells.

PubMed

Coryell, Virginia H; Stearns, Diane M

2006-11-07

Chromium picolinate (CrPic) is a popular dietary supplement, marketed to the public for weight loss, bodybuilding, and control of blood sugar. Recommendations for long-term use at high dosages have led to questions regarding its safety. Previous studies have reported that CrPic can cause chromosomal aberrations and mutations. The purpose of the current work was to compare the mutagenicity of CrPic as a suspension in acetone versus a solution in DMSO, and to characterize the hprt mutations induced by CrPic in CHO AA8 cells. Treatments of 2% acetone or 2% DMSO alone produced no significant increase in 6-thioguanine (6-TG)-resistant mutants after 48 h exposures. Mutants resistant to 6-TG were generated by exposing cells for 48 h to 80 microg/cm(2) CrPic in acetone or to 1.0mM CrPic in DMSO. CrPic in acetone produced an average induced mutation frequency (MF) of 56 per 10(6) surviving cells relative to acetone solvent. CrPic in acetone was 3.5-fold more mutagenic than CrPic in DMSO, which produced an MF of 16.2. Characterization of 61 total mutations in 48 mutants generated from exposure to CrPic in acetone showed that base substitutions comprised 33% of the mutations, with transversions being predominant; deletions made up 62% of the mutations, with one-exon deletions predominating; and 1-4 bp insertions made up 5% of the characterized mutations. CrPic induced a statistically greater number of deletions and a statistically smaller number of base substitutions than have been measured in spontaneously generated mutants. These data confirm previous studies showing that CrPic is mutagenic, and support the contention that further study is needed to verify the safety of CrPic for human consumption.

Osiris-Rex and Hayabusa2 Sample Cleanroom Design and Construction Planning at NASA-JSC

NASA Technical Reports Server (NTRS)

Righter, Kevin; Pace, Lisa F.; Messenger, Keiko

2018-01-01

Final Paper and not the abstract is attached. The OSIRIS-REx asteroid sample return mission launched to asteroid Bennu September 8, 2016. The spacecraft will arrive at Bennu in late 2019, orbit and map the asteroid, and perform a touch and go (TAG) sampling maneuver in July 2020. After confirma-tion of successful sample stowage, the spacecraft will return to Earth, and the sample return capsule (SRC) will land in Utah in September 2023. Samples will be recovered from Utah and then transported and stored in a new sample cleanroom at NASA Johnson Space Center in Houston. All curation-specific ex-amination and documentation activities related to Ben-nu samples will be conducted in the dedicated OSIRIS-REx sample cleanroom to be built at NASA-JSC.

The ISIS Mission Concept: An Impactor for Surface and Interior Science

NASA Technical Reports Server (NTRS)

Chesley, Steven R.; Elliot, John O.; Abell, Paul A.; Asphaug, Erik; Bhaskaran, Shyam; Lam, Try; Lauretta, Dante S.

2013-01-01

The Impactor for Surface and Interior Science (ISIS) mission concept is a kinetic asteroid impactor mission to the target of NASA's OSIRIS-REx (Origins-Spectral Interpretation-Resource Identification-Security-Regolith Explorer) asteroid sample return mission. The ISIS mission concept calls for the ISIS spacecraft, an independent and autonomous smart impactor, to guide itself to a hyper-velocity impact with 1999 RQ36 while the OSIRIS-REx spacecraft observes the collision. Later the OSIRIS-REx spacecraft descends to reconnoiter the impact site and measure the momentum imparted to the asteroid through the impact before departing on its journey back to Earth. In this paper we discuss the planetary science, human exploration and impact mitigation drivers for mission, and we describe the current mission concept and flight system design.

Emission-line maps with OSIRIS-TF: The case of M101

NASA Astrophysics Data System (ADS)

Méndez-Abreu, J.

2013-05-01

We investigate the suitability of GTC/OSIRIS Tunable Filters (TFs) for obtaining emission-line maps of extended objects. We developed a technique to reconstruct an emission-line image from a set of images taken at consecutive central wavelengths. We demonstrate the feasibility of the reconstruction method by generating a flux calibrated Hα image of the well-known spiral galaxy M101. We tested our emission-line fluxes and ratios by using data present in the literature. We found that the differences in both Hα fluxes and N II/Hα line ratios are ~15% and ~50%, respectively. These results are fully in agreement with the expected values for our observational setup. The proposed methodology will allow us to use OSIRIS/GTC to perform accurate spectrophotometric studies of extended galaxies in the local Universe.

OSIRIS-REx, Returning the Asteroid Sample

NASA Technical Reports Server (NTRS)

Ajluni, Thomas, M.; Everett, David F.; Linn, Timothy; Mink, Ronald; Willcockson, William; Wood, Joshua

2015-01-01

This paper addresses the technical aspects of the sample return system for the upcoming Origins, Spectral Interpretation, Resource Identification, and Security-Regolith Explorer (OSIRIS-REx) asteroid sample return mission. The overall mission design and current implementation are presented as an overview to establish a context for the technical description of the reentry and landing segment of the mission.The prime objective of the OSIRIS-REx mission is to sample a primitive, carbonaceous asteroid and to return that sample to Earth in pristine condition for detailed laboratory analysis. Targeting the near-Earth asteroid Bennu, the mission launches in September 2016 with an Earth reentry date of September 24, 2023.OSIRIS-REx will thoroughly characterize asteroid Bennu providing knowledge of the nature of near-Earth asteroids that is fundamental to understanding planet formation and the origin of life. The return to Earth of pristine samples with known geologic context will enable precise analyses that cannot be duplicated by spacecraft-based instruments, revolutionizing our understanding of the early Solar System. Bennu is both the most accessible carbonaceous asteroid and one of the most potentially Earth-hazardous asteroids known. Study of Bennu addresses multiple NASA objectives to understand the origin of the Solar System and the origin of life and will provide a greater understanding of both the hazards and resources in near-Earth space, serving as a precursor to future human missions to asteroids.This paper focuses on the technical aspects of the Sample Return Capsule (SRC) design and concept of operations, including trajectory design and reentry retrieval. Highlights of the mission are included below.The OSIRIS-REx spacecraft provides the essential functions for an asteroid characterization and sample return mission: attitude control propulsion power thermal control telecommunications command and data handling structural support to ensure successful rendezvous with Bennu characterization of Bennus properties delivery of the sampler to the surface, and return of the spacecraft to the vicinity of the Earth sample collection, performed by the Touch-and-Go Sample Acquisition Mechanism (TAGSAM), to acquire a regolith sample from the surface Earth re-entry and SRC recovery. Following sample collection, OSIRIS-REx drifts away from Bennu until the Asteroid Departure Maneuver is commanded on March 4, 2021, sending OSIRIS-REx on a ballistic return cruise to Earth. No additional large deterministic maneuvers are required to return the SRC to Earth. During the cruise, tracking and trajectory correction maneuvers (TCMs) are performed as necessary to precisely target the entry corridor. As OSIRIS-REx approaches Earth, the reentry plans are reviewed starting about a year before arrival, and preparations begin. The spacecraft is targeted away from the Earth until 7 days before entry. The final two trajectory correction maneuvers bring the spacecraft on target toward the Utah Test and Training Range (UTTR), with sufficient time for contingency resolution. The SRC releases 4 hours prior to atmospheric entry interface and, using the Stardust capsule heritage design, employs a traditional drogue and main parachute descent system for a soft touchdown.

Speed-limited particle-in-cell (SLPIC) simulation

NASA Astrophysics Data System (ADS)

Werner, Gregory; Cary, John; Jenkins, Thomas

2016-10-01

Speed-limited particle-in-cell (SLPIC) simulation is a new method for particle-based plasma simulation that allows increased timesteps in cases where the timestep is determined (e.g., in standard PIC) not by the smallest timescale of interest, but rather by an even smaller physical timescale that affects numerical stability. For example, SLPIC need not resolve the plasma frequency if plasma oscillations do not play a significant role in the simulation; in contrast, standard PIC must usually resolve the plasma frequency to avoid instability. Unlike fluid approaches, SLPIC retains a fully-kinetic description of plasma particles and includes all the same physical phenomena as PIC; in fact, if SLPIC is run with a PIC-compatible timestep, it is identical to PIC. However, unlike PIC, SLPIC can run stably with larger timesteps. SLPIC has been shown to be effective for finding steady-state solutions for 1D collisionless sheath problems, greatly speeding up computation despite a large ion/electron mass ratio. SLPIC is a relatively small modification of standard PIC, with no complexities that might degrade parallel efficiency (compared to PIC), and is similarly compatible with PIC field solvers and boundary conditions.

Rosetta/OSIRIS: Nucleus morphology and activity of comet 67P/Churyumov-Gerasimenko

NASA Astrophysics Data System (ADS)

Sierks, Holger

2015-08-01

Introduction: The Rosetta mission of the European Space Agency arrived on August 6, 2014, at the target comet 67P/Churyumov-Gerasimenko after 10 years of cruise. OSIRIS (Optical, Spectroscopic, and Infrared Remote Imaging System) is the scientific imaging system onboard Rosetta. It comprises a Narrow Angle Camera (NAC) for broad-band nucleus surface and dust studies and a Wide Angle Camera (WAC) for the wide field coma investigations.OSIRIS images the nucleus and the coma of comet 67P/C-G from the arrival throughout early mapping phase, PHILAE landing, and escort phase with close fly-by beginning of the year 2015.The team paper presents the surface morphology and activity of the nucleus as seen in gas, dust, and local jets and the larger scale coma studied by OSIRIS.Acknowledgements: OSIRIS was built by a consortium led by the Max-Planck-Institut für Sonnensystemforschung, Göttingen, Germany, in collaboration with CISAS, University of Padova, Italy, the Laboratoire d'Astrophysique de Marseille, France, the Instituto de Astrofísica de Andalucia, CSIC, Granada, Spain, the Scientific Support Office of the European Space Agency, Noordwijk, The Netherlands, the Instituto Nacional de Técnica Aeroespacial, Madrid, Spain, the Universidad Politéchnica de Madrid, Spain, the Department of Physics and Astronomy of Uppsala University, Sweden, and the Institut für Datentechnik und Kommunikationsnetze der Technischen Universität Braunschweig, Germany.Additional Information: The OSIRIS team is H. Sierks, C. Barbieri, P. Lamy, R. Rodrigo, D. Koschny, H. Rickman, J. Agarwal, M. A'Hearn, I. Bertini, F. Angrilli, M. A. Barucci, J. L. Bertaux, G. Cremonese, V. Da Deppo, B. Davidsson, S. Debei, M. De Cecco, S. Fornasier, M. Fulle, O. Groussin, C. Güttler, P. Gutierrez, S. Hviid, W. Ip, L. Jorda, H. U. Keller, J. Knollenberg, R. Kramm, E. Kührt, M. Küppers, L. Lara, M. Lazzarin, J. J. Lopez, S. Lowry, S. Marchi, F. Marzari, H. Michalik, S. Mottola, G. Naletto, N. Oklay, L. Sabau, N. Thomas, C. Tubiana, J-B. Vincent, P. Wenzel, Associate Scientists & Assistants.

The planetary spatial data infrastructure for the OSIRIS-REx mission

NASA Astrophysics Data System (ADS)

DellaGiustina, D. N.; Selznick, S.; Nolan, M. C.; Enos, H. L.; Lauretta, D. S.

2017-12-01

The primary objective of the Origins, Spectral Interpretation, Resource Identification, and Security-Regolith Explorer (OSIRIS-REx) mission is to return a pristine sample of carbonaceous material from primitive asteroid (101955) Bennu. Understanding the geospatial context of Bennu is critical to choosing a sample-site and also linking the nature of the sample to the global properties of Bennu and the broader asteroid population. We established a planetary spatial data infrastructure (PSDI) support the primary objective of OSIRIS-REx. OSIRIS-REx is unique among planetary missions in that all remote sensing is performed to support the sample return objective. Prior to sampling, OSIRIS-REx will survey Bennu for nearly two years to select and document the most valuable primary and backup sample sites. During this period, the mission will combine coordinated observations from five science instruments into four thematic maps: deliverability, safety, sampleability, and scientific value. The deliverability map assesses the probability that the flight dynamics team can deliver the spacecraft to the desired location. The safety map indicates the probability that physical hazards are present at the sample-site. The sampleability map quantifies the probability that a sample can be successfully collected from the surface. Finally, the scientific value map shows the probability that the collected sample contains organics and volatiles and also places the sample site in a definitive geological context relative to Bennu's history. The OSIRIS-REx Science Processing and Operations Center (SPOC) serves as the operational PSDI for the mission. The SPOC is tasked with intake of all data from the spacecraft and other ground sources and assimilating these data into a single comprehensive system for processing and presentation. The SPOC centralizes all geographic data of Bennu in a relational database and ensures that standardization and provenance are maintained throughout proximity operations.The SPOC is a live system that handles inputs from spacecraft and science instrument telemetry, and science data producers. It includes multiple levels of validation, both automated and manual to process all data in a robust and reliable manner and eventually deliver it to the NASA Planetary Data System for archive.

BRIEF COMMUNICATION: The negative ion flux across a double sheath at the formation of a virtual cathode

NASA Astrophysics Data System (ADS)

McAdams, R.; Bacal, M.

2010-08-01

For the case of negative ions from a cathode entering a plasma, the maximum negative ion flux and the positive ion flux before the formation of a virtual cathode have been calculated for particular plasma conditions. The calculation is based on a simple modification of an analysis of electron emission into a plasma containing negative ions. The results are in good agreement with a 1d3v PIC code model.

Design studies of the Ku-band, wide-band Gyro-TWT amplifier

NASA Astrophysics Data System (ADS)

Jung, Sang Wook; Lee, Han Seul; Jang, Kwong Ho; Choi, Jin Joo; Hong, Yong Jun; Shin, Jin Woo; So, Jun Ho; Won, Jong Hyo

2014-02-01

This paper reports a Ku-band, wide band Gyrotron-Traveling-wave-tube(Gyro-TWT) that is currently being developed at Kwangwoon University. The Gyro-TWT has a two stage linear tapered interaction circuit to obtain a wide operating bandwidth. The linearly-tapered interaction circuit and nonlinearly-tapered magnetic field gives the Gyro-TWT a wide operating bandwidth. The Gyro-TWT bandwidth is 23%. The 2d-Particle-in-cell(PIC) and MAGIC2d code simulation results are 17.3 dB and 24.34 kW, respectively for the maximum saturated output power. A double anode MIG was simulated with E-Gun code. The results were 0.7 for the transvers to the axial beam velocity ratio (=alpha) and a 2.3% axial velocity spread at 50 kV and 4 A. A magnetic field profile simulation was performed by using the Poisson code to obtain the grazing magnetic field of the entire interaction circuit with Poisson code.

The dust environment of 67P/Churyumov-Gerasimenko as seen through Rosetta/OSIRIS

NASA Astrophysics Data System (ADS)

Tubiana, Cecilia; Bertini, Ivano; Deller, Jakob; Drolshagen, Esther; Frattin, Elisa; Güttler, Carsten; Hofmann, Marc; Koschny, Detlef; Oklay, Nilda; Ott, Theresa; Shi, Xian; Sierks, Holger; Vincent, Jean-Baptiste; OSIRIS Team

2016-10-01

The ESA's Rosetta spacecraft had the unique opportunity to stay in the vicinity of the comet for two years, observing how the comet evolved while approaching the Sun, passing through perihelion and then moving outwards. OSIRIS, the Optical, Spectroscopic, and Infrared Remote Imaging System onboard Rosetta, imaged the nucleus and the dust environment of 67/Churyumov-Gerasimenko since the beginning of post-hibernation operations in March 2014. We focus here on dust studies carried on with OSIRIS.Images obtained in different filters in the visible wavelength range have been used to study the unresolved dust coma, investigating its diurnal and seasonal variations and providing insights into the dust composition. A correlation has been found between the level of diurnal activity and the region of the nucleus surface in sunlight, suggesting that the topography and/or composition of the surface play an important role. The overall activity increases while the comet is approaching the Sun, peaking about a month after perihelion. Comparison with ground-based observations will allow to understand if the dust coma behaves in similar ways at small scales - as observed by Rosetta/OSIRIS - and at large scales - as observed from ground. Several times during the mission, we acquired images spanning the phase angle range 0-165 degrees. They are used to determine the dust phase function in different wavelengths, its evolution with heliocentric distance and to investigate the intimate nature of cometary dust aggregates by solving the inverse scattering problem. A large amount of individual aggregates is present in the vicinity of 67P/Churyumov-Gerasimenko. We used OSIRIS NAC and WAC images to determine the aggregate properties: size and distance distributions, colors and rotation. Thanks to observations performed at different heliocentric distances, we address how those properties are changing with heliocentric distance.

Plasmon-induced charge separation: chemistry and wide applications.

PubMed

Tatsuma, Tetsu; Nishi, Hiroyasu; Ishida, Takuya

2017-05-01

Recent development of nanoplasmonics has stimulated chemists to utilize plasmonic nanomaterials for efficient and distinctive photochemical applications, and physicists to boldly go inside the "wet" chemistry world. The discovery of plasmon-induced charge separation (PICS) has even accelerated these trends. On the other hand, some confusion is found in discussions about PICS. In this perspective, we focus on differences between PICS and some other phenomena such as co-catalysis effect and plasmonic nanoantenna effect. In addition, materials and nanostructures suitable for PICS are shown, and characteristics and features unique to PICS are documented. Although it is well known that PICS has been applied to photovoltaics and photocatalysis, here light is shed on other applications that take better advantage of PICS, such as chemical sensing and biosensing, various photochromisms, photoswitchable functionalities and nanoscale photofabrication.

The use of polyion complex micelles to enhance the oral delivery of salmon calcitonin and transport mechanism across the intestinal epithelial barrier.

PubMed

Li, Na; Li, Xin-Ru; Zhou, Yan-Xia; Li, Wen-Jing; Zhao, Yong; Ma, Shu-Jin; Li, Jin-Wen; Gao, Ya-Jie; Liu, Yan; Wang, Xing-Lin; Yin, Dong-Dong

2012-12-01

The objective of the present study was to demonstrate the effect of polyanionic copolymer mPEG-grafted-alginic acid (mPEG-g-AA)-based polyion complex (PIC) micelles on enhancing the oral absorption of salmon calcitonin (sCT) in vivo and in vitro and identify the transepithelial transport mechanism of PIC micelles across the intestinal barrier. mPEG-g-AA was first successfully synthesized and characterized in cytotoxicity. The PIC micelles were approximately of 72 nm in diameter with a narrow distribution. The extremely significant enhancement of hypocalcemia efficacy of sCT-loaded PIC micelles in rats was evidenced by intraduodenal administration in comparison with sCT solution. The presence of mPEG-grafted-chitosan in PIC micelles had no favorable effect on this action in the referred content. In the Caco-2 transport studies, PIC micelles could significantly increase the permeability of sCT across Caco-2 monolayers without significantly affecting transepithelial electrical resistance values during the transport study. No evident alterations in the F-actin cytoskeleton were detected by confocal microscope observation following treatment of the cell monolayers with PIC micelles, which further certified the incapacity of PIC micelles to open the intercellular tight junctions. In addition, TEM observations showed that the intact PIC micelles were transported across the everted gut sac. These suggested that the transport of PIC micelles across Caco-2 cell monolayers involve a predominant transcytosis mechanism via endocytosis rather than paracellular pathway. Furthermore, PIC micelles were localized in both the cytoplasm and the nuclei observed by CLSM. Therefore, PIC micelles might be a potentially applicable tool for enhancing the oral absorption of cationic peptide and protein drugs. Copyright © 2012 Elsevier Ltd. All rights reserved.

The ePLAS code for Ignition Studies

NASA Astrophysics Data System (ADS)

Faehl, R. J.; Mason, R. J.; Kirkpatrick, R. C.

2012-10-01

The ePLAS code is a multi-fluid/PIC hybrid developing self-consistent E & B-fields by the Implicit Moment Method for stable calculations of high density plasma problems with voids on the electron Courant time scale. See: http://www.researchapplicationscorp.com. Here, we outline typical applications to: 1) short pulse driven electron transport along void (or high Z) insulated wires, and 2) the 2D development of shock ignition pressure peaks with B-fields. We outline the code's recent inclusion of SESAME EOS data, a DT/DD burn capability, a new option for K-alpha imaging of modeling output, and demonstrate a foil expansion tracked with either fluid or particle ions. Also, we describe a new super-hybrid extension of our implicit solver that permits full target dynamics studies on the ion Courant scale. Finally, we will touch on the very recent application of ePLAS to possible non-local/kinetic hydro effects NIF capsules.

ESCAP/POPIN Expert Working Group on Development of Population Information Centres and Networks, 20-23 June 1984, Bangkok, Thailand.

PubMed

1984-07-01

An overview of current population information programs at the regional, national, and global level was presented at a meeting of the Expert Working Group on Development of Population Information Centres and Networks. On the global level, the decentralized Population Information Network (POPIN) was established, consisting of population libraries, clearinghouses, information systems, and documentation centers. The Economic and Social Commission for Asia and the Pacific (ESCAP) Regional Population Information Centre (PIC) has actively promoted the standardization of methodologies for the collection and processing of data, the use of compatible terminology, adoption of classification systems, computer-assisted data and information handling, and improved programs of publication and infomration dissemination, within and among national centers. Among the national PICs, 83% are attached to the primary national family planning/fertility control unit and 17% are attached to demographic data, research, and analysis units. Lack of access to specialized information handling equipment such as microcomputers, word processors, and computer terminals remains a problem for PICs. Recommendations were made by the Expert Working Group to improve the functions of PICs: 1) the mandate and resoponsibilities of the PIC should be explicilty stated; 2) PICs should collect, process, and disseminate population information in the most effective format to workers in the population feild; 3) PICs should be given flexibility in the performance of activitites by their governing bodies; 4) short-term training should be provided in computerization and dissemination of information; 5) research and evaluation mechanisms for PIC activities should be developed; 6) PIC staff should prepare policy briefs for decision makers; 7) access to parent organizations should be given to nongovernment PICs; 8) study tours to foreign PICs should be organized for PIC staff; and 9) on-the-job training in indexing and abstracting should be provided. Networking among PICs can be further facilitated by written acquisition policies, automation of bibliographic information, common classification systems, and exchange of ideas and experience between various systems.

Feasibility study for using an extended three-wave model to simulate plasma-based backward Raman amplification in one spatial dimension

NASA Astrophysics Data System (ADS)

Wang, T.-L.; Michta, D.; Lindberg, R. R.; Charman, A. E.; Martins, S. F.; Wurtele, J. S.

2009-12-01

Results are reported of a one-dimensional simulation study comparing the modeling capability of a recently formulated extended three-wave model [R. R. Lindberg, A. E. Charman, and J. S. Wurtele, Phys. Plasmas 14, 122103 (2007); Phys. Plasmas 15, 055911 (2008)] to that of a particle-in-cell (PIC) code, as well as to a more conventional three-wave model, in the context of the plasma-based backward Raman amplification (PBRA) [G. Shvets, N. J. Fisch, A. Pukhov et al., Phys. Rev. Lett. 81, 4879 (1998); V. M. Malkin, G. Shvets, and N. J. Fisch, Phys. Rev. Lett. 82, 4448 (1999); Phys. Rev. Lett. 84, 1208 (2000)]. The extended three-wave model performs essentially as well as or better than a conventional three-wave description in all temperature regimes tested, and significantly better at the higher temperatures studied, while the computational savings afforded by the extended three-wave model make it a potentially attractive tool that can be used prior to or in conjunction with PIC simulations to model the kinetic effects of PBRA for nonrelativistic laser pulses interacting with underdense thermal plasmas. Very fast but reasonably accurate at moderate plasma temperatures, this model may be used to perform wide-ranging parameter scans or other exploratory analyses quickly and efficiently, in order to guide subsequent simulation via more accurate if intensive PIC techniques or other algorithms approximating the full Vlasov-Maxwell equations.

Particle-In-Cell Modeling For MJ Dense Plasma Focus with Varied Anode Shape

NASA Astrophysics Data System (ADS)

Link, A.; Halvorson, C.; Schmidt, A.; Hagen, E. C.; Rose, D.; Welch, D.

2014-10-01

Megajoule scale dense plasma focus (DPF) Z-pinches with deuterium gas fill are compact devices capable of producing 1012 neutrons per shot but past predictive models of large-scale DPF have not included kinetic effects such as ion beam formation or anomalous resistivity. We report on progress of developing a predictive DPF model by extending our 2D axisymmetric collisional kinetic particle-in-cell (PIC) simulations to the 1 MJ, 2 MA Gemini DPF using the PIC code LSP. These new simulations incorporate electrodes, an external pulsed-power driver circuit, and model the plasma from insulator lift-off through the pinch phase. The simulations were performed using a new hybrid fluid-to-kinetic model transitioning from a fluid description to a fully kinetic PIC description during the run-in phase. Simulations are advanced through the final pinch phase using an adaptive variable time-step to capture the fs and sub-mm scales of the kinetic instabilities involved in the ion beam formation and neutron production. Results will be present on the predicted effects of different anode configurations. This work performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory (LLNL) under Contract DE-AC52-07NA27344 and supported by the Laboratory Directed Research and Development Program (11-ERD-063) and the Computing Grand Challenge program at LLNL. This work supported by Office of Defense Nuclear Nonproliferation Research and Development within U.S. Department of Energy's National Nuclear Security Administration.

The HIBEAM Manual

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fawley, William M.

2000-02-01

HIBEAM is a 2 1/2D particle-in-cell (PIC) simulation code developed in the late 1990's in the Heavy-Ion Fusion research program at Lawrence Berkeley National Laboratory. The major purpose of HIBEAM is to simulate the transverse (i.e., X-Y) dynamics of a space-charge-dominated, non-relativistic heavy-ion beam being transported in a static accelerator focusing lattice. HIBEAM has been used to study beam combining systems, effective dynamic apertures in electrostatic quadrupole lattices, and emittance growth due to transverse misalignments. At present, HIBEAM runs on the CRAY vector machines (C90 and J90's) at NERSC, although it would be relatively simple to port the code tomore » UNIX workstations so long as IMSL math routines were available.« less

Comparison of Children With and Without ADHD on a New Pictorial Self-Assessment of Executive Functions.

PubMed

Bar-Ilan, Ruthie Traub; Cohen, Noa; Maeir, Adina

We examined the Pictorial Interview of Children's Metacognition and Executive Functions' (PIC-ME's) reliability and validity, targeting children's appraisal of their executive function (EF) in daily life. One hundred children with attention deficit hyperactivity disorder (ADHD) and 44 typically developing children (ages 5-10 yr) completed the PIC-ME. Parents completed the PIC-ME and Behavior Rating Inventory of Executive Function (BRIEF). Cronbach's α for the child PIC-ME was .914. A high correlation was found between the parent PIC-ME total and the BRIEF (r = .724). Comparisons between groups revealed significant differences on the parent PIC-ME (p < .0001) but none on the child PIC-ME. Children with ADHD identified a median of eight EF challenges they wanted to set as treatment goals. Results support the PIC-ME's initial reliability and validity among children with ADHD. Children were able to identify several EF challenges and engage in goal setting. Copyright © 2018 by the American Occupational Therapy Association, Inc.

Precise engineering of siRNA delivery vehicles to tumors using polyion complexes and gold nanoparticles.

PubMed

Kim, Hyun Jin; Takemoto, Hiroyasu; Yi, Yu; Zheng, Meng; Maeda, Yoshinori; Chaya, Hiroyuki; Hayashi, Kotaro; Mi, Peng; Pittella, Frederico; Christie, R James; Toh, Kazuko; Matsumoto, Yu; Nishiyama, Nobuhiro; Miyata, Kanjiro; Kataoka, Kazunori

2014-09-23

For systemic delivery of siRNA to solid tumors, a size-regulated and reversibly stabilized nanoarchitecture was constructed by using a 20 kDa siRNA-loaded unimer polyion complex (uPIC) and 20 nm gold nanoparticle (AuNP). The uPIC was selectively prepared by charge-matched polyionic complexation of a poly(ethylene glycol)-b-poly(L-lysine) (PEG-PLL) copolymer bearing ∼40 positive charges (and thiol group at the ω-end) with a single siRNA bearing 40 negative charges. The thiol group at the ω-end of PEG-PLL further enabled successful conjugation of the uPICs onto the single AuNP through coordinate bonding, generating a nanoarchitecture (uPIC-AuNP) with a size of 38 nm and a narrow size distribution. In contrast, mixing thiolated PEG-PLLs and AuNPs produced a large aggregate in the absence of siRNA, suggesting the essential role of the preformed uPIC in the formation of nanoarchitecture. The smart uPIC-AuNPs were stable in serum-containing media and more resistant against heparin-induced counter polyanion exchange, compared to uPICs alone. On the other hand, the treatment of uPIC-AuNPs with an intracellular concentration of glutathione substantially compromised their stability and triggered the release of siRNA, demonstrating the reversible stability of these nanoarchitectures relative to thiol exchange and negatively charged AuNP surface. The uPIC-AuNPs efficiently delivered siRNA into cultured cancer cells, facilitating significant sequence-specific gene silencing without cytotoxicity. Systemically administered uPIC-AuNPs showed appreciably longer blood circulation time compared to controls, i.e., bare AuNPs and uPICs, indicating that the conjugation of uPICs onto AuNP was crucial for enhancing blood circulation time. Finally, the uPIC-AuNPs efficiently accumulated in a subcutaneously inoculated luciferase-expressing cervical cancer (HeLa-Luc) model and achieved significant luciferase gene silencing in the tumor tissue. These results demonstrate the strong potential of uPIC-AuNP nanoarchitectures for systemic siRNA delivery to solid tumors.

Improved OSIRIS NO2 retrieval algorithm: description and validation

NASA Astrophysics Data System (ADS)

Sioris, Christopher E.; Rieger, Landon A.; Lloyd, Nicholas D.; Bourassa, Adam E.; Roth, Chris Z.; Degenstein, Douglas A.; Camy-Peyret, Claude; Pfeilsticker, Klaus; Berthet, Gwenaël; Catoire, Valéry; Goutail, Florence; Pommereau, Jean-Pierre; McLinden, Chris A.

2017-03-01

A new retrieval algorithm for OSIRIS (Optical Spectrograph and Infrared Imager System) nitrogen dioxide (NO2) profiles is described and validated. The algorithm relies on spectral fitting to obtain slant column densities of NO2, followed by inversion using an algebraic reconstruction technique and the SaskTran spherical radiative transfer model (RTM) to obtain vertical profiles of local number density. The validation covers different latitudes (tropical to polar), years (2002-2012), all seasons (winter, spring, summer, and autumn), different concentrations of nitrogen dioxide (from denoxified polar vortex to polar summer), a range of solar zenith angles (68.6-90.5°), and altitudes between 10.5 and 39 km, thereby covering the full retrieval range of a typical OSIRIS NO2 profile. The use of a larger spectral fitting window than used in previous retrievals reduces retrieval uncertainties and the scatter in the retrieved profiles due to noisy radiances. Improvements are also demonstrated through the validation in terms of bias reduction at 15-17 km relative to the OSIRIS operational v3.0 algorithm. The diurnal variation of NO2 along the line of sight is included in a fully spherical multiple scattering RTM for the first time. Using this forward model with built-in photochemistry, the scatter of the differences relative to the correlative balloon NO2 profile data is reduced.

A historical hypothesis of the first recorded neurosurgical operation: Isis, Osiris, Thoth, and the origin of the djed cross.

PubMed

Filler, Aaron G

2007-01-01

A new textual analysis of the central religious aspect of the ancient Egyptian creation myth reveals what appears to be a description of the oldest recorded neurosurgical operation, occurring circa 3000 BC. The analysis results in a hypothesis suggesting that traction reduction was used successfully to reverse a paralyzing cervical spine injury of an early Egyptian leader (Osiris), which inspired the story of his resurrection. The Egyptian mother god Isis, working with the god Thoth (the inventor of medicine), resurrects Osiris by treating his damaged cervical spine. Numerous references in the Papyrus of Ani (Book of the Dead) to Osiris regaining the strength and control of his legs are linked textually to the treatment of his spine. The connection between the intact spine and the ability to rise and stand is used as a distinct metaphor for life and death by the spinal representation of the "djed column" painted on the back of the numerous Egyptian sarcophagi for thousands of years. Controversy over the translation of the vertebral references in Egyptian texts is clarified by considering the specific neurosurgical meanings of hieroglyphs appearing in both the Edwin Smith medical papyrus and in the Papyrus of Ani, and in light of recent scholarly reassessments of those hieroglyphs in the Egyptological literature.

Designing to Sample the Unknown: Lessons from OSIRIS-REx Project Systems Engineering

NASA Technical Reports Server (NTRS)

Everett, David; Mink, Ronald; Linn, Timothy; Wood, Joshua

2017-01-01

On September 8, 2016, the third NASA New Frontiers mission launched on an Atlas V 411. The Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer (OSIRIS-REx) will rendezvous with asteroid Bennu in 2018, collect a sample in 2020, and return that sample to Earth in September 2023. The development team has overcome a number of challenges in order to design and build a system that will make contact with an unexplored, airless, low-gravity body. This paper will provide an overview of the mission, then focus in on the system-level challenges and some of the key system-level processes. Some of the lessons here are unique to the type of mission, like discussion of operating at a largely-unknown, low-gravity object. Other lessons, particularly from the build phase, have broad implications. The OSIRIS-REx risk management process was particularly effective in achieving an on-time and under-budget development effort. The systematic requirements management and verification and the system validation also helped identify numerous potential problems. The final assessment of the OSIRIS-REx performance will need to wait until the sample is returned in 2023, but this post-launch assessment will capture some of the key systems-engineering lessons from the development team.

The OSIRIS-Rex Asteroid Sample Return: Mission Operations Design

NASA Technical Reports Server (NTRS)

Gal-Edd, Jonathan; Cheuvront, Allan

2014-01-01

The OSIRIS-REx mission employs a methodical, phased approach to ensure success in meeting the missions science requirements. OSIRIS-REx launches in September 2016, with a backup launch period occurring one year later. Sampling occurs in 2019. The departure burn from Bennu occurs in March 2021. On September 24, 2023, the SRC lands at the Utah Test and Training Range (UTTR). Stardust heritage procedures are followed to transport the SRC to Johnson Space Center, where the samples are removed and delivered to the OSIRIS-REx curation facility. After a six-month preliminary examination period the mission will produce a catalog of the returned sample, allowing the worldwide community to request samples for detailed analysis.Traveling and returning a sample from an Asteroid that has not been explored before requires unique operations consideration. The Design Reference Mission (DRM) ties together space craft, instrument and operations scenarios. The project implemented lessons learned from other small body missions: APLNEAR, JPLDAWN and ESARosetta. The key lesson learned was expected the unexpected and implement planning tools early in the lifecycle. In preparation to PDR, the project changed the asteroid arrival date, to arrive one year earlier and provided additional time margin. STK is used for Mission Design and STKScheduler for instrument coverage analysis.

Effects of chromium(III) picolinate on cortisol and DHEAs secretion in H295R human adrenocortical cells.

PubMed

Kim, Beob G; Adams, Julye M; Jackson, Brian A; Lindemann, Merlin D

2010-02-01

Dietary chromium(III) picolinate (CrPic) effects on circulating steroid hormones have been reported in various experimental animals. However, direct effects of CrPic on adrenocortical steroidogenesis are uncertain. Therefore, the objective was to determine the effects of CrPic on cortisol and dehydroepiandrosterone sulfate (DHEAs) secretion from H295R cells. In experiment 1, a 24-h exposure to CrPic (0 to 200 microM) had both linear (p < 0.001) and quadratic (p < 0.001) effects on cortisol secretion from forskolin-stimulated cells with the highest cortisol secretion at 0.1 microM of CrPic and the lowest at 200 microM of CrPic. In experiment 2, a 48-h exposure to CrPic (200 microM) decreased cortisol (p < 0.07) release from forskolin-stimulated cells during a 24-h collection period. In experiment 3, a 48-h exposure to CrPic (100 microM) decreased cortisol (p < 0.05) and DHEAs (p < 0.01) from forskolin-stimulated cells during a 24-h sampling period. In experiment 4, a 24-h exposure to forskolin followed by a 24-h exposure to both forskolin and CrPic (100 and 200 microM) decreased both cortisol and DHEAs secretion (p < 0.01). This study suggests that at high concentrations, CrPic inhibits aspects of steroidogenesis in agonist-stimulated adrenocortical cells.

PIC Activation through Functional Interplay between Mediator and TFIIH.

PubMed

Malik, Sohail; Molina, Henrik; Xue, Zhu

2017-01-06

The multiprotein Mediator coactivator complex functions in large part by controlling the formation and function of the promoter-bound preinitiation complex (PIC), which consists of RNA polymerase II and general transcription factors. However, precisely how Mediator impacts the PIC, especially post-recruitment, has remained unclear. Here, we have studied Mediator effects on basal transcription in an in vitro transcription system reconstituted from purified components. Our results reveal a close functional interplay between Mediator and TFIIH in the early stages of PIC development. We find that under conditions when TFIIH is not normally required for transcription, Mediator actually represses transcription. TFIIH, whose recruitment to the PIC is known to be facilitated by the Mediator, then acts to relieve Mediator-induced repression to generate an active form of the PIC. Gel mobility shift analyses of PICs and characterization of TFIIH preparations carrying mutant XPB translocase subunit further indicate that this relief of repression is achieved through expending energy via ATP hydrolysis, suggesting that it is coupled to TFIIH's established promoter melting activity. Our interpretation of these results is that Mediator functions as an assembly factor that facilitates PIC maturation through its various stages. Whereas the overall effect of the Mediator is to stimulate basal transcription, its initial engagement with the PIC generates a transcriptionally inert PIC intermediate, which necessitates energy expenditure to complete the process. Copyright © 2016 Elsevier Ltd. All rights reserved.

Prevalence and characteristics of plateau iris configuration among American Caucasian, American Chinese and mainland Chinese subjects.

PubMed

Li, Yingjie; Wang, Ye Elaine; Huang, Guofu; Wang, Dandan; He, Mingguang; Qiu, Mary; Lin, Shan

2014-04-01

To investigate the prevalence, risk factors and characteristics of plateau iris configuration (PIC) among American Caucasian, American Chinese and mainland Chinese. This multicentre, cross-sectional study of non-glaucomatous subjects (40-80 years) included 111 American Caucasian, 116 American Chinese and 110 mainland Chinese. Prevalence of PIC based on ultrasound biomicroscopy imaging was compared among the different ethnic groups. Risk factors and anterior segment optical coherence tomography-measured iris and angle parameters in eyes with PIC were compared. The prevalence of PIC was 25.2% in American Caucasian, 24.1% in American Chinese and 20.9% in mainland Chinese (p=0.73). The presence of PIC was associated with more positive spherical equivalence (OR=1.31, p=0.002) and shorter axial length (OR=0.75, p=0.04). There were significant differences in angle recess area (ARA) (p=0.04), IT750 (p=0.007) and IT2000 (p<0.001) between Chinese and Caucasians who have PIC. The prevalence of PIC did not differ among American Caucasian, American Chinese and mainland Chinese. PIC was associated with non-myopia and shorter axial length. Chinese eyes with PIC had smaller ARA and thicker irides than Caucasian ones. PIC might be a physiological variation of the iris and ciliary body that exists in normal eyes, both in Chinese and Caucasians.

Plasmon-induced charge separation: chemistry and wide applications

PubMed Central

Nishi, Hiroyasu; Ishida, Takuya

2017-01-01

Recent development of nanoplasmonics has stimulated chemists to utilize plasmonic nanomaterials for efficient and distinctive photochemical applications, and physicists to boldly go inside the “wet” chemistry world. The discovery of plasmon-induced charge separation (PICS) has even accelerated these trends. On the other hand, some confusion is found in discussions about PICS. In this perspective, we focus on differences between PICS and some other phenomena such as co-catalysis effect and plasmonic nanoantenna effect. In addition, materials and nanostructures suitable for PICS are shown, and characteristics and features unique to PICS are documented. Although it is well known that PICS has been applied to photovoltaics and photocatalysis, here light is shed on other applications that take better advantage of PICS, such as chemical sensing and biosensing, various photochromisms, photoswitchable functionalities and nanoscale photofabrication. PMID:28507702

Bright ice spots on the nucleus of comet 67P/Churyumov-Gerasimenko as observed by Rosetta OSIRIS and VIRTIS instruments

NASA Astrophysics Data System (ADS)

Barucci, Maria Antonietta; Fulchignoni, Marcello; Pommerol, Antoine; Erard, Stéphane; Oklay, Nilda; Tosi, Federico; Capaccioni, Fabrizio; Sierks, Holger; Filacchione, Gianrico; Bockelee-Morvan, Dominique; Guettler, Carsten; Fornasier, Sonia; Raponi, Andrea; Deshapriya, J. D. P.; Feller, Clement; Ciarniello, Mauro; Leyrat, Cedric

2016-07-01

Since the Rosetta mission arrived at the comet 67P/Churyumov-Gerasimenko (67/P C-G) on August 2014, the comet nucleus has been mapped by both OSIRIS (Optical, Spectroscopic, and Infrared Remote Imaging System), and VIRTIS (Visible Infrared Thermal Imaging Spectrometer) acquiring a huge quantity of surface's images and spectra, producing the most detailed maps at the highest spatial resolution of a cometary nucleus. The OSIRIS imaging system (NAC & WAC) has a set of filters at different wavelengths from the ultraviolet (269 nm) to the near-infrared (989 nm). The OSIRIS imaging system has been the first instrument with the capability to map a comet surface at a high resolution reaching a maximum resolution of 11cm/px during the closest fly-by on February 14, 2015 at a distance of about 6 km from the nucleus surface while the VIRTIS spectro-imager (with two channels M and H) operates from 0.25 to 5m with medium and high spectral resolution. The spectral analysis on global scale from the VIRTIS data indicates that the nucleus presents different terrains covered by a very dark and dehydrated organic-rich material [1]. OSIRIS images indicate a morphologically complex and dark surface with a variety of terrain types and several intricate features [2]. The surface shows albedo variation and from the spectrophotometric analysis a large heterogeneity on the surface properties [3, 4, 5]. Limited evidences of exposed H2O ice have been found on the surface of 67/P C-G up to now [6, 7, 8], even though ices are considered to be a major constituent of cometary nuclei. The aim of this work is, taking advantage of the high resolution of the OSIRIS images, i) to detect the bright spots at all dimensions by albedo and spectral slope analyses, ii) to select those spots which could be resolved by VIRTIS and iii ) to deeply analyse the corresponding spectra. The OSIRIS analysis has been carried out on the colours and spectrophotometry of the whole 67/P C-G nucleus from images acquired since the first Rosetta bound orbits in August 2014 up to the end of 2015. The bright spots are spread everywhere on the surface. The analysis of the VIRTIS spectra on the selected positions by OSIRIS allowed us to detect eight spots with positive H2O ice signatures detection. The obtained results with the computed models will be presented and discussed. References : [1] Capaccioni et al. 2015. Science 347, DOI: 10.1126/science.aaa0628 [2] Sierks et al. 2015. Science 347, DOI: 10.1126/science.aaa1044 [3] Fornasier et al. 2015. A&A, 583, A30 [4] Ciarniello et al., 2015, A&A, 583, A31 [5] Oklay et al. 2016. A&A 586, A80 [6] Pommerol et al. 2015. A&A, 583, A25 [7] De Sanctis et al. 2015. Nature 525, 500 [8] Filacchione et al. 2016. Nature 529, 368.

``Illuminating'' electron diffusion regions of collisionless magnetic reconnection using electron agyrotropy

NASA Astrophysics Data System (ADS)

Scudder, Jack; Daughton, William

2008-06-01

Agyrotropy is a scalar measure of the departure of the pressure tensor from cylindrical symmetry about the local magnetic field direction. Ordinarily electrons are well modeled as gyrotropic with very small agyrotropy. Intensified layers of electron agyrotropy are demonstrated to highlight the thin electron gyroradius scale boundary regions adjoining separatrices, X and O lines of full particle simulations of collisionless magnetic reconnection. Examples are presented to show these effects in antiparallel and guide field geometries, pair plasmas, and simulations at a variety of mass ratios, including a hydrogen plasma. Agyrotropy has been determined from the PIC pressure tensor using a new, fast algorithm developed to correct discreteness contributions to the apparent agyrotropy. As a local scalar diagnostic, agyrotropy is shown to be potentially useful with single spacecraft data to identify the crossing or proximity of electron scale current layers, thus providing a kinetic level diagnosis of a given layer's ability to be a possible site of the collisionless reconnection process. Such kinetic tools are certainly complimentary to the other macroscopic signatures of reconnection. Because of the extreme circumstances required for electron agyrotropy, detection of these signatures with framing macroscopic signatures might prove useful for the discovery of new reconnection sites in nature and 3-D codes of collisionless reconnection. The agyrotropy in the 2-D PIC codes reflect long-lived bulges on the distribution function that appear to be organized by the direction and size of slowly evolving perpendicular electric fields in these layers and are not consistent with gyrophase bunching.

Tuning the Size of Nanoassembles: A Hierarchical Transfer of Information from Dendrimers to Polyion Complexes.

PubMed

Amaral, Sandra P; Tawara, Maun H; Fernandez-Villamarin, Marcos; Borrajo, Erea; Martínez-Costas, José; Vidal, Anxo; Riguera, Ricardo; Fernandez-Megia, Eduardo

2018-05-04

The generation of dendrimers is a powerful tool in the control of the size and biodistribution of polyion complexes (PIC). Using a combinatorial screening of six dendrimers (18-243 terminal groups) and five oppositely charged PEGylated copolymers, a dendrimer-to-PIC hierarchical transfer of structural information was revealed with PIC diameters that increased from 80 to 500 nm on decreasing the dendrimer generation. This rise in size, which was also accompanied by a micelle-to-vesicle transition, is interpreted according to a cone- to rod-shaped progression in the architecture of the unit PIC (uPIC). This precise size tuning enabled dendritic PICs to act as nanorulers for controlled biodistribution. Overall, a domino-like control of the size and biological properties of PIC that is not attainable with linear polymers is feasible through dendrimer generation. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Inter-annual Variability in Global Suspended Particulate Inorganic Carbon Inventory Using Space-based Measurements

NASA Astrophysics Data System (ADS)

Hopkins, J.; Balch, W. M.; Henson, S.; Poulton, A. J.; Drapeau, D.; Bowler, B.; Lubelczyk, L.

2016-02-01

Coccolithophores, the single celled phytoplankton that produce an outer covering of calcium carbonate coccoliths, are considered to be the greatest contributors to the global oceanic particulate inorganic carbon (PIC) pool. The reflective coccoliths scatter light back out from the ocean surface, enabling PIC concentration to be quantitatively estimated from ocean color satellites. Here we use datasets of AQUA MODIS PIC concentration from 2003-2014 (using the recently-revised PIC algorithm), as well as statistics on coccolithophore vertical distribution derived from cruises throughout the world ocean, to estimate the average global (surface and integrated) PIC standing stock and its associated inter-annual variability. In addition, we divide the global ocean into Longhurst biogeochemical provinces, update the PIC biomass statistics and identify those regions that have the greatest inter-annual variability and thus may exert the greatest influence on global PIC standing stock and the alkalinity pump.

46 CFR 13.301 - Original application for “Tankerman-PIC (Barge)” endorsement.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 1 2010-10-01 2010-10-01 false Original application for âTankerman-PIC (Barge)â endorsement. 13.301 Section 13.301 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY MERCHANT MARINE....301 Original application for “Tankerman-PIC (Barge)” endorsement. Each applicant for a “Tankerman-PIC...

Peroxydisulfate activation by [RuII(tpy)(pic)(H2O)]+. Kinetic, mechanistic and anti-microbial activity studies.

PubMed

Chatterjee, Debabrata; Banerjee, Priyabrata; Bose, Jagadeesh C K; Mukhopadhyay, Sudit

2012-03-07

The oxidation of [Ru(II)(tpy)(pic)H(2)O](+) (tpy = 2,2',6',2''-terpyridine; pic(-) = picolinate) by peroxidisulfate (S(2)O(8)(2-)) as precursor oxidant has been investigated kinetically by UV-VIS, IR and EPR spectroscopy. The overall oxidation of Ru(II)- to Ru(IV)-species takes place in a consecutive manner involving oxidation of [Ru(II)(tpy)(pic)H(2)O](+) to [Ru(III)(tpy)(pic)(OH)](+), and its further oxidation of to the ultimate product [Ru(IV)(tpy)(pic)(O)](+) complex. The time course of the reaction was followed as a function of [S(2)O(8)(2-)], ionic strength (I) and temperature. Kinetic data and activation parameters are interpreted in terms of an outer-sphere electron transfer mechanism. Anti-microbial activity of Ru(II)(tpy)(pic)H(2)O](+) complex by inhibiting the growth of Escherichia coli DH5α in presence of peroxydisulfate has been explored, and the results of the biological studies have been discussed in terms of the [Ru(IV)(tpy)(pic)(O)](+) mediated cleavage of chromosomal DNA of the bacteria.

Development of the micro pixel chamber based on MEMS technology

NASA Astrophysics Data System (ADS)

Takemura, T.; Takada, A.; Kishimoto, T.; Komura, S.; Kubo, H.; Matsuoka, Y.; Miuchi, K.; Miyamoto, S.; Mizumoto, T.; Mizumura, Y.; Motomura, T.; Nakamasu, Y.; Nakamura, K.; Oda, M.; Ohta, K.; Parker, J. D.; Sawano, T.; Sonoda, S.; Tanimori, T.; Tomono, D.; Yoshikawa, K.

2018-02-01

Micro pixel chambers (μ-PIC) are gaseous two-dimensional imaging detectors originally manufactured using printed circuit board (PCB) technology. They are used in MeV gamma-ray astronomy, medicalimaging, neutron imaging, the search for dark matter, and dose monitoring. The position resolution of the present μ-PIC is approximately 120 μm (RMS), however some applications require a fine position resolution of less than 100 μm. To this end, we have started to develop a μ-PIC based on micro electro mechanical system (MEMS) technology, which provides better manufacturing accuracy than PCB technology. Our simulation predicted the gains of MEMS μ-PICs to be twice those of PCB μ-PICs at the same anode voltage. We manufactured two MEMS μ-PICs and tested them to study their behavior. In these experiments, we successfully operated the fabricatedMEMS μ-PICs and we achieved a maximum gain of approximately 7×103 and collected their energy spectra under irradiation of X-rays from 55Fe. However, the measured gains of the MEMS μ-PICs were less than half of the values predicted in the simulations. We postulated that the gains of the MEMS μ-PICs are diminished by the effect of the silicon used as a semiconducting substrate.

Recent Progress and Future Plans for Fusion Plasma Synthetic Diagnostics Platform

NASA Astrophysics Data System (ADS)

Shi, Lei; Kramer, Gerrit; Tang, William; Tobias, Benjamin; Valeo, Ernest; Churchill, Randy; Hausammann, Loic

2015-11-01

The Fusion Plasma Synthetic Diagnostics Platform (FPSDP) is a Python package developed at the Princeton Plasma Physics Laboratory. It is dedicated to providing an integrated programmable environment for applying a modern ensemble of synthetic diagnostics to the experimental validation of fusion plasma simulation codes. The FPSDP will allow physicists to directly compare key laboratory measurements to simulation results. This enables deeper understanding of experimental data, more realistic validation of simulation codes, quantitative assessment of existing diagnostics, and new capabilities for the design and optimization of future diagnostics. The Fusion Plasma Synthetic Diagnostics Platform now has data interfaces for the GTS and XGC-1 global particle-in-cell simulation codes with synthetic diagnostic modules including: (i) 2D and 3D Reflectometry; (ii) Beam Emission Spectroscopy; and (iii) 1D Electron Cyclotron Emission. Results will be reported on the delivery of interfaces for the global electromagnetic PIC code GTC, the extended MHD M3D-C1 code, and the electromagnetic hybrid NOVAK eigenmode code. Progress toward development of a more comprehensive 2D Electron Cyclotron Emission module will also be discussed. This work is supported by DOE contract #DEAC02-09CH11466.

Storage of Maize in Purdue Improved Crop Storage (PICS) Bags

PubMed Central

2017-01-01

Interest in using hermetic technologies as a pest management solution for stored grain has risen in recent years. One hermetic approach, Purdue Improved Crop Storage (PICS) bags, has proven successful in controlling the postharvest pests of cowpea. This success encouraged farmers to use of PICS bags for storing other crops including maize. To assess whether maize can be safely stored in PICS bags without loss of quality, we carried out laboratory studies of maize grain infested with Sitophilus zeamais (Motshulsky) and stored in PICS triple bags or in woven polypropylene bags. Over an eight month observation period, temperatures in the bags correlated with ambient temperature for all treatments. Relative humidity inside PICS bags remained constant over this period despite the large changes that occurred in the surrounding environment. Relative humidity in the woven bags followed ambient humidity closely. PICS bags containing S. zeamais-infested grain saw a significant decline in oxygen compared to the other treatments. Grain moisture content declined in woven bags, but remained high in PICS bags. Seed germination was not significantly affected over the first six months in all treatments, but declined after eight months of storage when infested grain was held in woven bags. Relative damage was low across treatments and not significantly different between treatments. Overall, maize showed no signs of deterioration in PICS bags versus the woven bags and PICS bags were superior to woven bags in terms of specific metrics of grain quality. PMID:28072835

Use of OsiriX in developing a digital radiology teaching library.

PubMed

Shamshuddin, S; Matthews, H R

2014-10-01

Widespread adoption of digital imaging in clinical practice and for the image-based examinations of the Royal College of Radiologists has created a desire to provide a digital radiology teaching library in many hospital departments around the UK. This article describes our experience of using OsiriX software in developing digital radiology teaching libraries. Copyright © 2014 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

Smart Power: New power integrated circuit technologies and their applications

NASA Astrophysics Data System (ADS)

Kuivalainen, Pekka; Pohjonen, Helena; Yli-Pietilae, Timo; Lenkkeri, Jaakko

1992-05-01

Power Integrated Circuits (PIC) is one of the most rapidly growing branches of the semiconductor technology. The PIC markets has been forecast to grow from 660 million dollars in 1990 to 1658 million dollars in 1994. It has even been forecast that at the end of the 1990's the PIC markets would correspond to the value of the whole semiconductor production in 1990. Automotive electronics will play the leading role in the development of the standard PIC's. Integrated motor drivers (36 V/4 A), smart integrated switches (60 V/30 A), solenoid drivers, integrated switch-mode power supplies and regulators are the latest standard devices of the PIC manufactures. ASIC (Application Specific Integrated Circuits) PIC solutions are needed for the same reasons as other ASIC devices: there are no proper standard devices, a company has a lot of application knowhow, which should be kept inside the company, the size of the product must be reduced, and assembly costs are wished to be reduced by decreasing the number of discrete devices. During the next few years the most probable ASIC PIC applications in Finland will be integrated solenoid and motor drivers, an integrated electronic lamp ballast circuit and various sensor interface circuits. Application of the PIC technologies to machines and actuators will strongly be increased all over the world. This means that various PIC's, either standard PIC's or full custom ASIC circuits, will appear in many products which compete with the corresponding Finnish products. Therefore the development of the PIC technologies must be followed carefully in order to immediately be able to apply the latest development in the smart power technologies and their design methods.

E-type asteroid (2867) Steins as imaged by OSIRIS on board Rosetta.

PubMed

Keller, H U; Barbieri, C; Koschny, D; Lamy, P; Rickman, H; Rodrigo, R; Sierks, H; A'Hearn, M F; Angrilli, F; Barucci, M A; Bertaux, J-L; Cremonese, G; Da Deppo, V; Davidsson, B; De Cecco, M; Debei, S; Fornasier, S; Fulle, M; Groussin, O; Gutierrez, P J; Hviid, S F; Ip, W-H; Jorda, L; Knollenberg, J; Kramm, J R; Kührt, E; Küppers, M; Lara, L-M; Lazzarin, M; Lopez Moreno, J; Marzari, F; Michalik, H; Naletto, G; Sabau, L; Thomas, N; Wenzel, K-P; Bertini, I; Besse, S; Ferri, F; Kaasalainen, M; Lowry, S; Marchi, S; Mottola, S; Sabolo, W; Schröder, S E; Spjuth, S; Vernazza, P

2010-01-08

The European Space Agency's Rosetta mission encountered the main-belt asteroid (2867) Steins while on its way to rendezvous with comet 67P/Churyumov-Gerasimenko. Images taken with the OSIRIS (optical, spectroscopic, and infrared remote( )imaging system) cameras on board Rosetta show that Steins is an oblate body with an effective spherical diameter of 5.3 kilometers. Its surface does not show color variations. The morphology of Steins is dominated by linear faults and a large 2.1-kilometer-diameter crater near its south pole. Crater counts reveal a distinct lack of small craters. Steins is not solid rock but a rubble pile and has a conical appearance that is probably the result of reshaping due to Yarkovsky-O'Keefe-Radzievskii-Paddack (YORP) spin-up. The OSIRIS images constitute direct evidence for the YORP effect on a main-belt asteroid.

The Keck OSIRIS Nearby AGN (KONA) Survey: AGN Fueling and Feedback

NASA Astrophysics Data System (ADS)

Hicks, Erin K. S.; Müller-Sánchez, Francisco; Malkan, Matthew A.; Yu, Po-Chieh

In an effort to better constrain the relevant physical processes dictating the co-evolution of supermassive black holes and the galaxies in which they reside we turn to local Seyfert AGN. It is only with these local AGN that we can reach the spatial resolution needed to adequately characterize the inflow and outflow mechanisms thought to be the driving forces in establishing the relationship between black holes and their host galaxies at higher redshift. We present the first results from the KONA (Keck OSIRIS Nearby AGN) survey, which takes advantage of the integral field unit OSIRIS plus laser and natural guide star adaptive optics to probe down to scales of 5-30 parsecs in a sample of 40 local Seyfert galaxies. With these K-band data we measure the two-dimensional distribution and kinematics of the nuclear stars, molecular gas, and ionized gas within the central few hundred parsecs.

Thermophysical Characteristics of OSIRIS-REx Target Asteroid (101955) Bennu

NASA Astrophysics Data System (ADS)

Yu, Liangliang; Ji, Jianghui

2016-01-01

In this work, we investigate the thermophysical properties, including thermal inertia, roughness fraction and surface grain size of OSIRIS-REx target asteroid (101955) Bennu by using a thermophysical model with the recently updated 3D radar-derived shape model (Nolan et al., 2013) and mid-infrared observations (Müller et al. 2012, Emery et al., 2014). We find that the asteroid bears an effective diameter of 510+6 -40 m, a geometric albedo of 0.047+0.0083 -0.0011, a roughness fraction of 0.04+0.26 -0.04, and thermal inertia of 240+440 -60 Jm-2s-0.5K-1 for our best-fit solution. The best-estimate thermal inertia suggests that fine-grained regolith may cover a large portion of Bennu's surface, where a grain size may vary from 1.3 to 31 mm. Our outcome suggests that Bennu is suitable for the OSIRIS-REx mission to return samples to Earth.

E-Type Asteroid (2867) Steins as Imaged by OSIRIS on Board Rosetta

NASA Astrophysics Data System (ADS)

Keller, H. U.; Barbieri, C.; Koschny, D.; Lamy, P.; Rickman, H.; Rodrigo, R.; Sierks, H.; A'Hearn, M. F.; Angrilli, F.; Barucci, M. A.; Bertaux, J.-L.; Cremonese, G.; Da Deppo, V.; Davidsson, B.; De Cecco, M.; Debei, S.; Fornasier, S.; Fulle, M.; Groussin, O.; Gutierrez, P. J.; Hviid, S. F.; Ip, W.-H.; Jorda, L.; Knollenberg, J.; Kramm, J. R.; Kührt, E.; Küppers, M.; Lara, L.-M.; Lazzarin, M.; Moreno, J. Lopez; Marzari, F.; Michalik, H.; Naletto, G.; Sabau, L.; Thomas, N.; Wenzel, K.-P.; Bertini, I.; Besse, S.; Ferri, F.; Kaasalainen, M.; Lowry, S.; Marchi, S.; Mottola, S.; Sabolo, W.; Schröder, S. E.; Spjuth, S.; Vernazza, P.

2010-01-01

The European Space Agency’s Rosetta mission encountered the main-belt asteroid (2867) Steins while on its way to rendezvous with comet 67P/Churyumov-Gerasimenko. Images taken with the OSIRIS (optical, spectroscopic, and infrared remote imaging system) cameras on board Rosetta show that Steins is an oblate body with an effective spherical diameter of 5.3 kilometers. Its surface does not show color variations. The morphology of Steins is dominated by linear faults and a large 2.1-kilometer-diameter crater near its south pole. Crater counts reveal a distinct lack of small craters. Steins is not solid rock but a rubble pile and has a conical appearance that is probably the result of reshaping due to Yarkovsky-O’Keefe-Radzievskii-Paddack (YORP) spin-up. The OSIRIS images constitute direct evidence for the YORP effect on a main-belt asteroid.

An Independent Orbit Determination Simulation for the OSIRIS-REx Asteroid Sample Return Mission

NASA Technical Reports Server (NTRS)

Getzandanner, Kenneth; Rowlands, David; Mazarico, Erwan; Antreasian, Peter; Jackman, Coralie; Moreau, Michael

2016-01-01

After arriving at the near-Earth asteroid (101955) Bennu in late 2018, the OSIRIS-REx spacecraft will execute a series of observation campaigns and orbit phases to accurately characterize Bennu and ultimately collect a sample of pristine regolith from its surface. While in the vicinity of Bennu, the OSIRIS-REx navigation team will rely on a combination of ground-based radiometric tracking data and optical navigation (OpNav) images to generate and deliver precision orbit determination products. Long before arrival at Bennu, the navigation team is performing multiple orbit determination simulations and thread tests to verify navigation performance and ensure interfaces between multiple software suites function properly. In this paper, we will summarize the results of an independent orbit determination simulation of the Orbit B phase of the mission performed to test the interface between the OpNav image processing and orbit determination software packages.

Seagrass meadows as a globally significant carbonate reservoir

NASA Astrophysics Data System (ADS)

Mazarrasa, I.; Marbà, N.; Lovelock, C. E.; Serrano, O.; Lavery, P. S.; Fourqurean, J. W.; Kennedy, H.; Mateo, M. A.; Krause-Jensen, D.; Steven, A. D. L.; Duarte, C. M.

2015-03-01

There has been a growing interest in quantifying the capacity of seagrass ecosystems to act as carbon sinks as a natural way of offsetting anthropogenic carbon emissions to the atmosphere. However, most of the efforts have focused on the organic carbon (POC) stocks and accumulation rates and ignored the inorganic carbon (PIC) fraction, despite important carbonate pools associated with calcifying organisms inhabiting the meadows, such as epiphytes and benthic invertebrates, and despite the relevance that carbonate precipitation and dissolution processes have in the global carbon cycle. This study offers the first assessment of the global PIC stocks in seagrass sediments using a synthesis of published and unpublished data on sediment carbonate concentration from 402 vegetated and 34 adjacent un-vegetated sites. PIC stocks in the top 1 m sediments ranged between 3 and 1660 Mg PIC ha-1, with an average of 654 ± 24 Mg PIC ha-1, exceeding about 5 fold those of POC reported in previous studies. Sedimentary carbonate stocks varied across seagrass communities, with meadows dominated by Halodule, Thalassia or Cymodocea supporting the highest PIC stocks, and tended to decrease polewards at a rate of -8 ± 2 Mg PIC ha-1 degree-1 of latitude (GLM, p < 0.0003). Using PIC concentration and estimates of sediment accretion in seagrass meadows, mean PIC accumulation rates in seagrass sediments is 126.3 ± 0.7 g PIC m-2 y-1. Based on the global extent of seagrass meadows (177 000 to 600 000 km2), these ecosystems globally store between 11 and 39 Pg of PIC in the top meter of sediment and accumulate between 22 and 76 Tg PIC y-1, representing a significant contribution to the carbonate dynamics of coastal areas. Despite that these high rates of carbonate accumulation imply CO2 emissions from precipitation, seagrass meadows are still strong CO2 sinks as demonstrates the comparison of carbon (POC and POC) stocks between vegetated and adjacent un-vegetated sediments.

Seagrass meadows as a globally significant carbonate reservoir

NASA Astrophysics Data System (ADS)

Mazarrasa, I.; Marbà, N.; Lovelock, C. E.; Serrano, O.; Lavery, P. S.; Fourqurean, J. W.; Kennedy, H.; Mateo, M. A.; Krause-Jensen, D.; Steven, A. D. L.; Duarte, C. M.

2015-08-01

There has been growing interest in quantifying the capacity of seagrass ecosystems to act as carbon sinks as a natural way of offsetting anthropogenic carbon emissions to the atmosphere. However, most of the efforts have focused on the particulate organic carbon (POC) stocks and accumulation rates and ignored the particulate inorganic carbon (PIC) fraction, despite important carbonate pools associated with calcifying organisms inhabiting the meadows, such as epiphytes and benthic invertebrates, and despite the relevance that carbonate precipitation and dissolution processes have in the global carbon cycle. This study offers the first assessment of the global PIC stocks in seagrass sediments using a synthesis of published and unpublished data on sediment carbonate concentration from 403 vegetated and 34 adjacent un-vegetated sites. PIC stocks in the top 1 m of sediment ranged between 3 and 1660 Mg PIC ha-1, with an average of 654 ± 24 Mg PIC ha-1, exceeding those of POC reported in previous studies by about a factor of 5. Sedimentary carbonate stocks varied across seagrass communities, with meadows dominated by Halodule, Thalassia or Cymodocea supporting the highest PIC stocks, and tended to decrease polewards at a rate of -8 ± 2 Mg PIC ha-1 per degree of latitude (general linear model, GLM; p < 0.0003). Using PIC concentrations and estimates of sediment accretion in seagrass meadows, the mean PIC accumulation rate in seagrass sediments is found to be 126.3 ± 31.05 g PIC m-2 yr-1. Based on the global extent of seagrass meadows (177 000 to 600 000 km2), these ecosystems globally store between 11 and 39 Pg of PIC in the top metre of sediment and accumulate between 22 and 75 Tg PIC yr-1, representing a significant contribution to the carbonate dynamics of coastal areas. Despite the fact that these high rates of carbonate accumulation imply CO2 emissions from precipitation, seagrass meadows are still strong CO2 sinks as demonstrated by the comparison of carbon (PIC and POC) stocks between vegetated and adjacent un-vegetated sediments.

Transport Simulations for Fast Ignition on NIF

NASA Astrophysics Data System (ADS)

Strozzi, D. J.; Tabak, M.; Grote, D. P.; Town, R. P. J.; Kemp, A. J.

2009-11-01

Calculations of the transport and deposition of a relativistic electron beam into fast-ignition fuel configurations are presented. The hybrid PIC code LSP is used, run in implicit mode and with fluid background particles. The electron beam distribution is chosen based on explicit PIC simulations of the short-pulse LPI. These generally display two hot-electron temperatures, one close to the ponderomotive scaling and one that is much lower. Fast-electron collisions utilize the formulae of J. R. Davies [S. Atzeni et al., Plasma Phys. Controlled Fusion 51 (2009)], and are done with a conservative, relativistic grid-based method similar to Lemons et al., J. Comput. Phys. 228 (2009). We include energy loss off both bound and free electrons in partially-ionized media (such as a gold cone), and have started to use realistic ionization and non-ideal EOS models. We have found the fractional energy coupling into the dense fuel is higher for CD than DT targets, due to the enhanced resistivity and resulting magnetic fields. The coupling enhancement due to magnetic fields and beam characteristics (such as angular spectrum) will be quantified.

Laser Cooling for Heavy-Ion Fusion (HIF)

NASA Astrophysics Data System (ADS)

Ho, D. D.-M.; Brandon, S.; Lee, Y.

1997-05-01

A critical requirement for HIF is the ability to focus space-charge dominated beams onto a millimeter-size spot. However, chromatic aberration can result in a substantial fraction of the beam ions falling outside the spot radius. Because of the space-charge force, correcting the chromatic aberration using sextupoles is impractical. Success in laser cooling of low-current ion beams in storage rings leads us to explore the application of laser cooling to HIF. Basic scheme: After the beams have been accelerated to the desired energy by the recirculating induction linac, we let the beams coast around at constant energy. For efficient interaction between the laser and the beam ions, we use Ba+ beams. We use two lasers to pump the transitions in the Ba+ for generating the laser force FL. There is also an auxiliary force Fa, which is in the opposition direction of FL, provided by the induction cores. The momentum spread along the beam can be compressed by FL and Fa. We will present preliminary PIC simulations using the PIC code CONDOR. Potential difficulties caused by velocity space instabilities will be discussed.

3D PIC-MCC simulations of discharge inception around a sharp anode in nitrogen/oxygen mixtures

NASA Astrophysics Data System (ADS)

Teunissen, Jannis; Ebert, Ute

2016-08-01

We investigate how photoionization, electron avalanches and space charge affect the inception of nanosecond pulsed discharges. Simulations are performed with a 3D PIC-MCC (particle-in-cell, Monte Carlo collision) model with adaptive mesh refinement for the field solver. This model, whose source code is available online, is described in the first part of the paper. Then we present simulation results in a needle-to-plane geometry, using different nitrogen/oxygen mixtures at atmospheric pressure. In these mixtures non-local photoionization is important for the discharge growth. The typical length scale for this process depends on the oxygen concentration. With 0.2% oxygen the discharges grow quite irregularly, due to the limited supply of free electrons around them. With 2% or more oxygen the development is much smoother. An almost spherical ionized region can form around the electrode tip, which increases in size with the electrode voltage. Eventually this inception cloud destabilizes into streamer channels. In our simulations, discharge velocities are almost independent of the oxygen concentration. We discuss the physical mechanisms behind these phenomena and compare our simulations with experimental observations.

NIMROD Modeling of Sawtooth Modes Using Hot-Particle Closures

NASA Astrophysics Data System (ADS)

Kruger, Scott; Jenkins, T. G.; Held, E. D.; King, J. R.

2015-11-01

In DIII-D shot 96043, RF heating gives rise to an energetic ion population that alters the sawtooth stability boundary, replacing conventional sawtooth cycles by longer-period, larger-amplitude `giant sawtooth' oscillations. We explore the use of particle-in-cell closures within the NIMROD code to numerically represent the RF-induced hot-particle distribution, and investigate the role of this distribution in determining the altered mode onset threshold and subsequent nonlinear evolution. Equilibrium reconstructions from the experimental data are used to enable these detailed validation studies. Effects of other parameters on the sawtooth behavior, such as the plasma Lundquist number and hot-particle beta-fraction, are also considered. The fast energetic particles present many challenges for the PIC closure. We review new algorithm and performance improvements to address these challenges, and provide a preliminary assessment of the efficacy of the PIC closure versus a continuum model for energetic particle modeling. We also compare our results with those of, and discuss plans for a more complete validation campaign for this discharge. Supported by US Department of Energy via the SciDAC Center for Extended MHD Modeling (CEMM).

DOE Office of Scientific and Technical Information (OSTI.GOV)

Friedman, A.; Barnard, J. J.; Cohen, R. H.

The Heavy Ion Fusion Science Virtual National Laboratory(a collaboration of LBNL, LLNL, and PPPL) is using intense ion beams to heat thin foils to the"warm dense matter" regime at<~;; 1 eV, and is developing capabilities for studying target physics relevant to ion-driven inertial fusion energy. The need for rapid target heating led to the development of plasma-neutralized pulse compression, with current amplification factors exceeding 50 now routine on the Neutralized Drift Compression Experiment (NDCX). Construction of an improved platform, NDCX-II, has begun at LBNL with planned completion in 2012. Using refurbished induction cells from the Advanced Test Accelerator at LLNL,more » NDCX-II will compress a ~;;500 ns pulse of Li+ ions to ~;;1 ns while accelerating it to 3-4 MeV over ~;;15 m. Strong space charge forces are incorporated into the machine design at a fundamental level. We are using analysis, an interactive 1D PIC code (ASP) with optimizing capabilities and centroid tracking, and multi-dimensional Warpcode PIC simulations, to develop the NDCX-II accelerator. This paper describes the computational models employed, and the resulting physics design for the accelerator.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Friedman, A; Barnard, J J; Cohen, R H

The Heavy Ion Fusion Science Virtual National Laboratory (a collaboration of LBNL, LLNL, and PPPL) is using intense ion beams to heat thin foils to the 'warm dense matter' regime at {approx}< 1 eV, and is developing capabilities for studying target physics relevant to ion-driven inertial fusion energy. The need for rapid target heating led to the development of plasma-neutralized pulse compression, with current amplification factors exceeding 50 now routine on the Neutralized Drift Compression Experiment (NDCX). Construction of an improved platform, NDCX-II, has begun at LBNL with planned completion in 2012. Using refurbished induction cells from the Advanced Testmore » Accelerator at LLNL, NDCX-II will compress a {approx}500 ns pulse of Li{sup +} ions to {approx} 1 ns while accelerating it to 3-4 MeV over {approx} 15 m. Strong space charge forces are incorporated into the machine design at a fundamental level. We are using analysis, an interactive 1D PIC code (ASP) with optimizing capabilities and centroid tracking, and multi-dimensional Warpcode PIC simulations, to develop the NDCX-II accelerator. This paper describes the computational models employed, and the resulting physics design for the accelerator.« less

Australian Validation of the Hierarchical Personality Inventory for Children (HiPIC)

ERIC Educational Resources Information Center

Hopkinson, Laura; Watt, Dianne; Roodenburg, John

2014-01-01

The Hierarchical Personality Inventory for Children (HiPIC) is a developmentally appropriate parent-report measure of the Five Factor Model (FFM) that has been validated in several European languages but only recently in English. The English translation of the HiPIC was evaluated in an Australian context. Parent-rated HiPIC scores were obtained…

Neuromodulation impact on nonlinear firing behavior of a reduced model motoneuron with the active dendrite

PubMed Central

Kim, Hojeong; Heckman, C. J.

2014-01-01

Neuromodulatory inputs from brainstem systems modulate the normal function of spinal motoneurons by altering the activation properties of persistent inward currents (PICs) in their dendrites. However, the effect of the PIC on firing outputs also depends on its location in the dendritic tree. To investigate the interaction between PIC neuromodulation and PIC location dependence, we used a two-compartment model that was biologically realistic in that it retains directional and frequency-dependent electrical coupling between the soma and the dendrites, as seen in multi-compartment models based on full anatomical reconstructions of motoneurons. Our two-compartment approach allowed us to systematically vary the coupling parameters between the soma and the dendrite to accurately reproduce the effect of location of the dendritic PIC on the generation of nonlinear (hysteretic) motoneuron firing patterns. Our results show that as a single parameter value for PIC activation was either increased or decreased by 20% from its default value, the solution space of the coupling parameter values for nonlinear firing outputs was drastically reduced by approximately 80%. As a result, the model tended to fire only in a linear mode at the majority of dendritic PIC sites. The same results were obtained when all parameters for the PIC activation simultaneously changed only by approximately ±10%. Our results suggest the democratization effect of neuromodulation: the neuromodulation by the brainstem systems may play a role in switching the motoneurons with PICs at different dendritic locations to a similar mode of firing by reducing the effect of the dendritic location of PICs on the firing behavior. PMID:25309410

The long-term quality of life in patients with persistent inflammation-immunosuppression and catabolism syndrome after severe acute pancreatitis: A retrospective cohort study.

PubMed

Yang, Na; Li, Baiqiang; Ye, Bo; Ke, Lu; Chen, Faxi; Lu, Guotao; Jiang, Fangfang; Tong, Zhihui; Li, Jieshou; Li, Weiqin

2017-12-01

To explore clinical characteristics and long-term quality of life (QOL) in severe acute pancreatitis (SAP) patients with persistent inflammation-immunosuppression and catabolism syndrome (PICS). SAP patients admitted to ICU were eligible for the retrospective cohort study if they needed prolonged intensive care (>14days). Post-ICU QOL was assessed by a questionnaire, including 36-item Short Form Health Survey (SF-36) and record of re-work in a long-term follow-up. 214 SAP patients were enrolled, in which 149 (69.6%) patients met the criteria of PICS. PICS patients had more complications and ICU days compared to non-PICS patients (P<0.001), and their post-ICU mortality was higher (P=0.046). When adjusted for confounders, PICS was independently associated with higher post-ICU mortality (hazard ratio 4.5; 95% CI, 1.2 to 16.3; P=0.024). The 36-item Short Form Health Survey (SF-36) score was lower for PICS group in six subscales (P<0.001). Only 28.8% patients in the PICS group returned to work compared to 60% patients in the non-PICS group (P=0.001) CONCLUSIONS: SAP patients with prolonged ICU stay had a high morbidity of PICS, which was a risk factor for the post-ICU mortality and poor long-term QOL. Copyright © 2017 Elsevier Inc. All rights reserved.

Diamond fly cutting of aluminum thermal infrared flat mirrors for the OSIRIS-REx Thermal Emission Spectrometer (OTES) instrument

NASA Astrophysics Data System (ADS)

Groppi, Christopher E.; Underhill, Matthew; Farkas, Zoltan; Pelham, Daniel

2016-07-01

We present the fabrication and measurement of monolithic aluminum flat mirrors designed to operate in the thermal infrared for the OSIRIS-Rex Thermal Emission Spectrometer (OTES) space instrument. The mirrors were cut using a conventional fly cutter with a large radius diamond cutting tool on a high precision Kern Evo 3-axis CNC milling machine. The mirrors were measured to have less than 150 angstroms RMS surface error.

Retrieval of subvisual cirrus cloud optical thickness from limb-scatter measurements

NASA Astrophysics Data System (ADS)

Wiensz, J. T.; Degenstein, D. A.; Lloyd, N. D.; Bourassa, A. E.

2013-01-01

We present a technique for estimating the optical thickness of subvisual cirrus clouds detected by OSIRIS (Optical Spectrograph and Infrared Imaging System), a limb-viewing satellite instrument that measures scattered radiances from the UV to the near-IR. The measurement set is composed of a ratio of limb radiance profiles at two wavelengths that indicates the presence of cloud-scattering regions. Cross-sections and phase functions from an in situ database are used to simulate scattering by cloud-particles. With appropriate configurations discussed in this paper, the SASKTRAN successive-orders of scatter radiative transfer model is able to simulate accurately the in-cloud radiances from OSIRIS. Configured in this way, the model is used with a multiplicative algebraic reconstruction technique (MART) to retrieve the cloud extinction profile for an assumed effective cloud particle size. The sensitivity of these retrievals to key auxiliary model parameters is shown, and it is shown that the retrieved extinction profile, for an assumed effective cloud particle size, models well the measured in-cloud radiances from OSIRIS. The greatest sensitivity of the retrieved optical thickness is to the effective cloud particle size. Since OSIRIS has an 11-yr record of subvisual cirrus cloud detections, the work described in this manuscript provides a very useful method for providing a long-term global record of the properties of these clouds.

Stellar Occultations in the Coma of Comet 67/P Chuyumov-Gerasimenko Observed by the OSIRIS Camera System

NASA Astrophysics Data System (ADS)

Moissl, Richard; Kueppers, Michael

2016-10-01

In this paper we present the results of an analysis on a large part of the existing Image data from the OSIRIS camera system onboard the Rosetta Spacecraft, in which stars of sufficient brightness (down to a limiting magnitude of 6) have been observed through the coma of Comet 67/P Churyumov-Gerasimenko ("C-G"). Over the course of the Rosetta main mission the Coma of the comet underwent large changes in density and structure, owed to the changing insolation along the orbit of C-G. We report on the changes of the stellar signals in the wavelength ranges, covered by the filters of the OSIRIS Narrow-Angle (NAC) and Wide-Angle (WAC) cameras.Acknowledgements: OSIRIS was built by a consortium led by the Max-Planck-Institut für Sonnensystemforschung, Göttingen, Germany, in collaboration with CISAS, University of Padova, Italy, the Laboratoire d'Astrophysique de Marseille, France, the Instituto de Astrofísica de Andalucia, CSIC, Granada, Spain, the Scientific Support Office of the European Space Agency, Noordwijk, The Netherlands, the Instituto Nacional de Técnica Aeroespacial, Madrid, Spain, the Universidad Politéchnica de Madrid, Spain, the Department of Physics and Astronomy of Uppsala University, Sweden, and the Institut für Datentechnik und Kommunikationsnetze der Technischen Universität Braunschweig, Germany.

Kinetic electron model for plasma thruster plumes

NASA Astrophysics Data System (ADS)

Merino, Mario; Mauriño, Javier; Ahedo, Eduardo

2018-03-01

A paraxial model of an unmagnetized, collisionless plasma plume expanding into vacuum is presented. Electrons are treated kinetically, relying on the adiabatic invariance of their radial action integral for the integration of Vlasov's equation, whereas ions are treated as a cold species. The quasi-2D plasma density, self-consistent electric potential, and electron pressure, temperature, and heat fluxes are analyzed. In particular, the model yields the collisionless cooling of electrons, which differs from the Boltzmann relation and the simple polytropic laws usually employed in fluid and hybrid PIC/fluid plume codes.

OSA Proceedings of the Topical Meeting (5th) on Short-Wave Length Coherent Radiation: Generation and Applications Held in Monterey, California on 8-10 April 1991. Volume 11

DTIC Science & Technology

1992-05-22

PIC simulation code to study several of the constraints imposed by plasma phenomena on the propagation of ultrashort high intensity laser pulses in...and radiation spectrum of free electrons in the focus of an ultrashort high intensity laser pulse is solved. Motion and radiation of electrons in a...higher harmonics. These studies are intended as a prelude to experiments with high intensity ultrashort laser pulses . To investigate the motion of

Nail-like targets for laser plasma interaction experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pasley, J; Wei, M; Shipton, E

2007-12-18

The interaction of ultra-high power picosecond laser pulses with solid targets is of interest both for benchmarking the results of hybrid particle in cell (PIC) codes and also for applications to re-entrant cone guided fast ignition. We describe the construction of novel targets in which copper/titanium wires are formed into 'nail-like' objects by a process of melting and micromachining, so that energy can be reliably coupled to a 24 {micro}m diameter wire. An extreme-ultraviolet image of the interaction of the Titan laser with such a target is shown.

Polygonal Impact Craters on selected Minor Bodies: Rhea, Dione, Tethys, Ceres, and Vesta

NASA Astrophysics Data System (ADS)

Neidhart, Tanja; Leitner, Johannes; Firneis, Maria

2017-04-01

A polygonal impact crater (PIC) is a crater that does not have a full circular shape in plane view but consists of straight crater rim segments. PICs are common on all objects in our solar system that show a cratered surface. Previous studies showed that PICs make up about 10-25% of craters on Mercury, Venus, Mars, and the Moon [1, 2, 3, 4]. Although there have been several studies on PICs on the terrestrial planets, and the Moon there are only very few investigations on PICs on minor bodies, even though there exist surface maps of Rhea, Tethys, Dione, Ceres, and Vesta that have an appropriate resolution. The aim of this study is to get more information about the abundance and characteristics of PICs on these objects. We analysed all approved craters on Rhea, Dione, Tethys, Ceres, and Vesta using images provided by the IAU/NASA/USGS Planetary Database [5]. For the classification of PICs the definition by [2] was used which states that a crater is polygonal if it consists of at least two straight crater rim segments having a discernable angle. In total 417 impact craters were examined and 227 of them were classified as polygonal. On Rhea about 48% of the approved craters are PICs, on Dione 59%, on Tethys 34%, on Ceres 74%, and on Vesta 56%. The comparison with studies on PICs on terrestrial planets, and the Moon conducted by [1, 2, 3, 4] showed that the percentage of PICs found in this study is much higher. Most of the PICs have two or three straight rim segments and only few PICs are hexagonal or pentagonal. The mean angle between the straight rims yields 121° for Rhea, 124° for Dione, 123° for Tethys, 133° for Ceres, and 134° for Vesta. These angles are well in accordance to an average angle of 112° on Mercury [1]. Also the size distribution of PICs is in accordance to results by [4] who proved that PICs seem to favor small to middle size diameters. The largest diameters of non-polygonal craters on Vesta range from 0.6 km to 450 km while the diameters of PICs only range from 3.1 km to 53.2 km [5]. The study proves that a large number of polygonal impact craters on Rhea, Dione, Tethys, Ceres, and Vesta exist but it is still unclear why the fraction of PICs on these bodies is much higher than for terrestrial planets and the Moon. One possible solution could be the different composition of the surfaces of these bodies in comparison to the terrestrial planets but for definite answers to this question further understanding of the formation process of PICs, which is still unclear, is necessary. References: [1] Weihs G. T. et al. (2015) Planet. Space Sci., 111, 77-82. [2] Aittola M. et al. (2010) Icarus, 205, 356-363. [3] Öhman et al. (2008) Meteoritics & Planet. Sci., 43, 1605-1628. [4] Öhman et al. (2010) Geol. Soc. Spec. Pap., 465, 51-65. [5] IAU/NASA/USGS Planetary Database. (2016), http://planetarynames.wr.usgs.gov/.

A Database Design for the Brazilian Air Force Military Personnel Control System.

DTIC Science & Technology

1987-06-01

GIVEN A RECNum GET MOVING HISTORICAL". 77 SEL4 PlC X(70) VALUE ". 4. GIVEN A RECNUM GET NOMINATION HISTORICAL". 77 SEL5 PIC X(70) VALUE it 5. GIVEN A...WHERE - "°RECNUM = :RECNUM". 77 SQL-SEL3-LENGTH PIC S9999 VALUE 150 COMP. 77 SQL- SEL4 PIC X(150) VALUE "SELECT ABBREV,DTNOM,DTEXO,SITN FROM...NOMINATION WHERE RECNUM 77 SQL- SEL4 -LENGTH PIC S9999 VALUE 150 COMP. 77 SQL-SEL5 PIC X(150) VALUE "SELECT ABBREVDTDES,DTWAIVER,SITD FROM DESIG WHERE RECNUM It

p-( sup 125 I)iodoclonidine is a partial agonist at the alpha 2-adrenergic receptor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gerhardt, M.A.; Wade, S.M.; Neubig, R.R.

1990-08-01

The binding properties of p-(125I)iodoclonidine (( 125I)PIC) to human platelet membranes and the functional characteristics of PIC are reported. (125I)PIC bound rapidly and reversibly to platelet membranes, with a first-order association rate constant (kon) at room temperature of 8.0 +/- 2.7 x 10(6) M-1 sec-1 and a dissociation rate constant (koff) of 2.0 +/- 0.8 x 10(-3) sec-1. Scatchard plots of specific (125I)PIC binding (0.1-5 nM) were linear, with a Kd of 1.2 +/- 0.1 nM. (125I)PIC bound to the same number of high affinity sites as the alpha 2-adrenergic receptor (alpha 2-AR) full agonist (3H) bromoxidine (UK14,304), which representedmore » approximately 40% of the sites bound by the antagonist (3H)yohimbine. Guanosine 5'-(beta, gamma-imido)triphosphate greatly reduced the amount of (125I)PIC bound (greater than 80%), without changing the Kd of the residual binding. In competition experiments, the alpha 2-AR-selective ligands yohimbine, bromoxidine, oxymetazoline, clonidine, p-aminoclonidine, (-)-epinephrine, and idazoxan all had Ki values in the low nanomolar range, whereas prazosin, propranolol, and serotonin yielded Ki values in the micromolar range. Epinephrine competition for (125I)PIC binding was stereoselective. Competition for (3H)bromoxidine binding by PIC gave a Ki of 1.0 nM (nH = 1.0), whereas competition for (3H)yohimbine could be resolved into high and low affinity components, with Ki values of 3.7 and 84 nM, respectively. PIC had minimal agonist activity in inhibiting adenylate cyclase in platelet membranes, but it potentiated platelet aggregation induced by ADP with an EC50 of 1.5 microM. PIC also inhibited epinephrine-induced aggregation, with an IC50 of 5.1 microM. Thus, PIC behaves as a partial agonist in a human platelet aggregation assay. (125I)PIC binds to the alpha 2B-AR in NG-10815 cell membranes with a Kd of 0.5 +/- 0.1 nM.« less

Modelling observations of the inner gas and dust coma of comet 67P/Churyumov-Gerasimenko using ROSINA/COPS and OSIRIS data: First results

NASA Astrophysics Data System (ADS)

Marschall, R.; Su, C. C.; Liao, Y.; Thomas, N.; Altwegg, K.; Sierks, H.; Ip, W.-H.; Keller, H. U.; Knollenberg, J.; Kührt, E.; Lai, I. L.; Rubin, M.; Skorov, Y.; Wu, J. S.; Jorda, L.; Preusker, F.; Scholten, F.; Gracia-Berná, A.; Gicquel, A.; Naletto, G.; Shi, X.; Vincent, J.-B.

2016-05-01

Context. This paper describes the initial modelling of gas and dust data acquired in August and September 2014 from the European Space Agency's Rosetta spacecraft when it was in close proximity to the nucleus of comet 67P/Churyumov-Gerasimenko. Aims: This work is an attempt to provide a self-consistent model of the innermost gas and dust coma of the comet, as constrained by the Rosetta Orbiter Spectrometer for Ion and Neutral Analysis (ROSINA) data set for the gas and by the Optical, Spectroscopic, and Infrared Remote Imaging System (OSIRIS) data set for the dust. Methods: The model uses a previously developed shape model for the nucleus, and from this the water sublimation rate and gas temperatures at the surface are computed with a simple thermal model. The gas expansion is modelled with a 3D parallel implementation of a Direct Simulation Monte Carlo algorithm. A dust drag algorithm is then used to produce dust densities in the coma, which are then converted to brightnesses using Mie theory and a line-of-sight integration. Results: We show that a purely insolation-driven model for surface outgassing does not produce a reasonable fit to ROSINA/COPS data. A stronger source in the "neck" region of the nucleus (region Hapi) is needed to match the observed modulation of the gas density in detail. This agrees with OSIRIS data, which shows that the dust emission from the "neck" was dominant in the August-September 2014 time frame. The current model matches this observation reasonably if a power index of 2-3 for the dust size distribution is used. A better match to the OSIRIS data is seen by using a single large particle size for the coma. Conclusions: We have shown possible solutions to the gas and dust distributions in the inner coma, which are consistent with ROSINA and OSIRIS data.

Thermal History of Near-Earth Asteroids: Implications for OSIRIS-REx Asteroid Sample Return

NASA Astrophysics Data System (ADS)

Springmann, Alessondra; Lauretta, Dante S.

2016-10-01

The connection between orbital and temperature history of small Solar System bodies has only been studied through modeling. The upcoming OSIRIS-REx asteroid sample return mission provides an opportunity to connect thermal modeling predictions with laboratory studies of meteorites to predict past heating and thus dynamical histories of bodies such as OSIRIS-REx mission target asteroid (101955) Bennu. Bennu is a desirable target for asteroid sample return due to its inferred primitive nature, likely 4.5 Gyr old, with chemistry and mineralogy established in the first 10 Myr of solar system history (Lauretta et al. 2015). Delbo & Michel (2011) studied connections between the temperature and orbital history of Bennu. Their results suggest that the surface of Bennu (assuming no regolith turnover) has a 50% probability of being heated to 500 K in the past. Further, the Delbo & Michel simulations show that the temperature within the asteroid below the top layer of regolith could remain at temperatures ~100 K below that of the surface. The Touch-And-Go Sample Acquisition Mechanism on OSIRIS-REx could access both the surface and near surface regolith, collecting primitive asteroid material for study in Earth-based laboratories in 2023. To quantify the effects of thermal metamorphism on the Bennu regolith, laboratory heating experiments on carbonaceous chondrite meteorites with compositions likely similar to that of Bennu were conducted from 300-1200 K. These experiments show mobilization and volatilization of a suite of labile elements (sulfur, mercury, arsenic, tellurium, selenium, antimony, and cadmium) at temperatures that could be reached by asteroids that cross Mercury's orbit. We are able to quantify element loss with temperature for several carbonaceous chondrites and use these results to constrain past orbital histories of Bennu. When OSIRIS-REx samples arrive for analysis we will be able to measure labile element loss in the material, determine maximum past temperature of the samples, and predict the past orbital and thermal history of Bennu.

Limb-Nadir Matching Using Non-Coincident NO2 Observations: Proof of Concept and the OMI-minus-OSIRIS Prototype Product

NASA Technical Reports Server (NTRS)

Adams, Cristen; Normand, Elise N.; Mclinden, Chris A.; Bourassa, Adam E.; Lloyd, Nicholas D.; Degenstein, Douglas A.; Krotkov, Nickolay A.; Rivas, Maria Belmonte; Boersma, K. Folkert; Eskes, Henk

2016-01-01

A variant of the limb-nadir matching technique for deriving tropospheric NO2 columns is presented in which the stratospheric component of the NO2 slant column density (SCD) measured by the Ozone Monitoring Instrument (OMI) is removed using non-coincident profiles from the Optical Spectrograph and InfraRed Imaging System (OSIRIS). In order to correct their mismatch in local time and the diurnal variation of stratospheric NO2, OSIRIS profiles, which were measured just after sunrise, were mapped to the local time of OMI observations using a photochemical boxmodel. Following the profile time adjustment, OSIRIS NO2 stratospheric vertical column densities (VCDs) were calculated. For profiles that did not reach down to the tropopause, VCDs were adjusted using the photochemical model. Using air mass factors from the OMI Standard Product (SP), a new tropospheric NO2 VCD product - referred to as OMI-minus-OSIRIS (OmO) - was generated through limb-nadir matching. To accomplish this, the OMI total SCDs were scaled using correction factors derived from the next-generation SCDs that improve upon the spectral fitting used for the current operational products. One year, 2008, of OmO was generated for 60 deg S to 60 deg N and a cursory evaluation was performed. The OmO product was found to capture the main features of tropospheric NO2, including a background value of about 0.3 x 10(exp 15) molecules per sq cm over the tropical Pacific and values comparable to the OMI operational products over anthropogenic source areas. While additional study is required, these results suggest that a limb-nadir matching approach is feasible for the removal of stratospheric NO2 measured by a polar orbiter from a nadir-viewing instrument in a geostationary orbit such as Tropospheric Emissions: Monitoring of Pollution (TEMPO) or Sentinel-4.

PaDe - The particle detection program

NASA Astrophysics Data System (ADS)

Ott, T.; Drolshagen, E.; Koschny, D.; Poppe, B.

2016-01-01

This paper introduces the Particle Detection program PaDe. Its aim is to analyze dust particles in the coma of the Jupiter-family comet 67P/Churyumov-Gerasimenko which were recorded by the two OSIRIS (Optical, Spectroscopic, and Infrared Remote Imaging System) cameras onboard the ESA spacecraft Rosetta, see e.g. Keller et al. (2007). In addition to working with the Rosetta data, the code was modified to work with images from meteors. It was tested with data recorded by the ICCs (Intensified CCD Cameras) of the CILBO-System (Canary Island Long-Baseline Observatory) on the Canary Islands; compare Koschny et al. (2013). This paper presents a new method for the position determination of the observed meteors. The PaDe program was written in Python 3.4. Its original intent is to find the trails of dust particles in space from the OSIRIS images. For that it determines the positions where the trail starts and ends. They were found using a fit following the so-called error function (Andrews, 1998) for the two edges of the profiles. The positions where the intensities fall to the half maximum were found to be the beginning and end of the particle. In the case of meteors, this method can be applied to find the leading edge of the meteor. The proposed method has the potential to increase the accuracy of the position determination of meteors dramatically. Other than the standard method of finding the photometric center, our method is not influenced by any trails or wakes behind the meteor. This paper presents first results of this ongoing work.

Effects of supplemental nanoparticle trivalent chromium on the nutrient utilization, growth performance and serum traits of broilers.

PubMed

Lin, Y C; Huang, J T; Li, M Z; Cheng, C Y; Lien, T F

2015-02-01

The aim of this study was to investigate the effect of dietary supplementation of nanoparticle trivalent chromium on nutrient utilization, growth performance and serum traits of broilers. This study included two trials. In trial 1, 32 three-week-old broilers were divided into four groups: the control, chromium chloride (CrCl3), chromium picolinate (CrPic) and nanoparticle chromium picolinate (NanoCrPic). Chromium was added at a 1200 μg/kg level to evaluate the nutrient and chromium utilization. In trial 2, 160 one-day-old broilers were randomly divided into four groups as in trial 1, with four replicates. The results of trial 1 indicated that the chromium utilization is as follows: NanoCrPic > CrPic > CrCl3 and control groups, with significant differences between groups (p < 0.05). Crude fat utilization in CrCl3 group was lower than in that the control group (p < 0.05). The results of trial 2 indicated that feed intake of 4-5 weeks showed better result in the CrCl3 group than that in the CrPic group (p < 0.05). The results of serum traits indicated that the LDL-cholesterol in the NanoCrPic groups was lower than that in the CrPic group (p < 0.05). The NanoCrpic and CrPic groups showed significantly increased serum chromium concentration when compared with the control and CrCl3 groups; the triglyceride level in the CrCl3 group was lower than that in the CrPic group (p < 0.05). This study concluded that compared with CrPic, NanoCrpic supplementation could increase chromium utilization and lower the serum LDL-cholesterol of broilers. Journal of Animal Physiology and Animal Nutrition © 2014 Blackwell Verlag GmbH.

Positioning irrigation of contrast cystography for diagnosis of occult vesicoureteric reflux: association with technetium-99m dimercaptosuccinic acid scans.

PubMed

Berger, Christoph; Becker, Tanja; Koen, Mark; Zeino, Mazen; Fitz, Friedrich; Beheshti, Mohsen; Wolf-Kohlmeier, Iris; Haim, Silke; Riccabona, Marcus

2013-12-01

Positioning irrigation of contrast (PIC) cystography identifies occult or PIC vesicoureteral reflux (PIC-VUR) in children with recurrent febrile urinary tract infections (UTI) but no vesicoureteric reflux (VUR) on standard voiding cystourethrogram (VCUG). We sought to identify the relationship between PIC-VUR and renal scarring in technetium-99m dimercaptosuccinic acid (DMSA) scans. We retrospectively analysed PIC cystograms and DMSA scans for 154 kidneys in 81 children (65 girls; 16 boys; median age, 4.7 years; range, 0.9-15.2). Renal scarring was graded on a scale of 0-3. DMSA scans were pathologic in 66 patients (81%). Children had experienced mean 3.8 febrile UTI (range 1-25). Forty-seven (58%) children had a history of reflux, including 15 (19%) with previous anti-reflux operations. Indications for PIC cystography were recurrence of febrile UTI after either bilateral negative VCUG (66 children) or unilateral VUR (15 children) with contralateral/bilateral scarring or reflux that had changed sides in subsequent VCUGs. PIC-VUR was bilateral in 63, unilateral in 12, and absent in 6 children. Statistically significant associations between PIC-VUR grade and severity of renal scarring were identified in inter-individual (n = 77, p = 0.017) and intra-individual (refluxing vs. nonrefluxing kidney; n = 12, p = 0.008) analyses. After excluding patients with history of VUR, statistical significance was maintained in inter-individual analysis (n = 49; p = 0.018). The data suggest an association between PIC-VUR and severity of renal scarring, and legitimise the use of PIC cystography in children with renal scarring due to recurrent febrile UTI but negative findings on VCUG. Copyright © 2012 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved.

Quantification of Poly(I:C)-Mediated Protection against Genital Herpes Simplex Virus Type 2 Infection

PubMed Central

Herbst-Kralovetz, Melissa M.; Pyles, Richard B.

2006-01-01

Alternative strategies for controlling the growing herpes simplex virus type 2 (HSV-2) epidemic are needed. A novel class of immunomodulatory microbicides has shown promise as antiherpetics, including intravaginally applied CpG-containing oligodeoxynucleotides that stimulate toll-like receptor 9 (TLR9). In the current study, we quantified protection against experimental genital HSV-2 infection provided by an alternative nucleic acid-based TLR agonist, polyinosine-poly(C) (PIC) (TLR3 agonist). Using a protection quantification paradigm, groups of mice were PIC treated and then subdivided into groups challenged with escalating doses of HSV-2. Using this paradigm, a temporal window of PIC efficacy for single applications was defined as 1 day prior to (prophylactic) through 4 h after (therapeutic) viral challenge. PIC treatment within this window protected against 10-fold-higher HSV-2 challenges, as indicated by increased 50% infectious dose values relative to those for vehicle-treated controls. Disease resolution and survival were significantly enhanced by repetitive PIC doses. Using optimal PIC regimens, cytokine induction was evaluated in murine vaginal lavages and in human vaginal epithelial cells. Similar induction patterns were observed, with kinetics that explained the limited durability of PIC-afforded protection. Daily PIC delivery courses did not generate sustained cytokine levels in murine vaginal fluids that would be indicative of local immunotoxicity. No evidence of immunotoxicity was observed in selected organs that were analyzed following repetitive vaginal PIC doses. Animal and in vitro data indicate that PIC may prove to be a valuable preventative microbicide and/or therapeutic agent against genital herpes by increasing resistance to HSV-2 and enhancing disease resolution following a failure of prevention. PMID:17005677

Particle model of a cylindrical inductively coupled ion source

NASA Astrophysics Data System (ADS)

Ippolito, N. D.; Taccogna, F.; Minelli, P.; Cavenago, M.; Veltri, P.

2017-08-01

In spite of the wide use of RF sources, a complete understanding of the mechanisms regulating the RF-coupling of the plasma is still lacking so self-consistent simulations of the involved physics are highly desirable. For this reason we are developing a 2.5D fully kinetic Particle-In-Cell Monte-Carlo-Collision (PIC-MCC) model of a cylindrical ICP-RF source, keeping the time step of the simulation small enough to resolve the plasma frequency scale. The grid cell dimension is now about seven times larger than the average Debye length, because of the large computational demand of the code. It will be scaled down in the next phase of the development of the code. The filling gas is Xenon, in order to minimize the time lost by the MCC collision module in the first stage of development of the code. The results presented here are preliminary, with the code already showing a good robustness. The final goal will be the modeling of the NIO1 (Negative Ion Optimization phase 1) source, operating in Padua at Consorzio RFX.

The Danish version of the questionnaire on pain communication: preliminary validation in cancer patients.

PubMed

Jacobsen, R; Møldrup, C; Christrup, L; Sjøgren, P; Hansen, O B

2009-07-01

The modified version of the patients' Perceived Involvement in Care Scale (M-PICS) is a tool designed to assess cancer patients' perceptions of patient-health care provider pain communication process. The objective of this study was to examine the psychometric properties of the shortened Danish version of the M-PICS (SDM-PICS). The validated English version of the M-PICS was translated into Danish following the repeated back-translation procedure. Cancer patients were recruited for the study from specialized pain management facilities. Thirty-three patients responded to the SDM-PICS, Danish Barriers Questionnaire II, Hospital Anxiety and Depression Scale, and Brief Pain Inventory Pain Severity Scale. A factor analysis of the SDM-PICS resulted in two factors: Factor one, patient information, consisted of four items assessing the extent to which the patient shared information with his/her health care provider, and Factor two, health care provider information, consisted of four items measuring the degree to which a health care provider was perceived as the one who shares information. Two separate items addressed the perceived level of information exchange between the patient and the health care provider. The SDM-PICS total had an internal consistency of 0.88. The SDM-PICS scores were positively related to pain relief and inversely related to the measures of cognitive pain management barriers, anxiety, and reported pain levels. The SDM-PICS seems to be a reliable and valid measure of perceived patient-health care provider communication in the context of cancer pain.

Influence of RNA Strand Rigidity on Polyion Complex Formation with Block Catiomers.

PubMed

Hayashi, Kotaro; Chaya, Hiroyuki; Fukushima, Shigeto; Watanabe, Sumiyo; Takemoto, Hiroyasu; Osada, Kensuke; Nishiyama, Nobuhiro; Miyata, Kanjiro; Kataoka, Kazunori

2016-03-01

Polyion complexes (b-PICs) are prepared by mixing single- or double-stranded oligo RNA (aniomer) with poly(ethylene glycol)-b-poly(L-lysine) (PEG-PLL) (block catiomer) to clarify the effect of aniomer chain rigidity on association behaviors at varying concentrations. Here, a 21-mer single-stranded RNA (ssRNA) (persistence length: 1.0 nm) and a 21-mer double-stranded RNA (small interfering RNA, siRNA) (persistence length: 62 nm) are compared. Both oligo RNAs form a minimal charge-neutralized ionomer pair with a single PEG-PLL chain, termed unit b-PIC (uPIC), at low concentrations (<≈ 0.01 mg mL(-1)). Above the critical association concentration (≈ 0.01 mg mL(-1)), ssRNA b-PICs form secondary associates, PIC micelles, with sizes up to 30-70 nm, while no such multimolecular assembly is observed for siRNA b-PICs. The entropy gain associated with the formation of a segregated PIC phase in the multimolecular PIC micelles may not be large enough for rigid siRNA strands to compensate with appreciably high steric repulsion derived from PEG chains. Chain rigidity appears to be a critical parameter in polyion complex association. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Response of plasma facing components in Tokamaks due to intense energy deposition using Particle-In-Cell (PIC) methods

NASA Astrophysics Data System (ADS)

Genco, Filippo

Damage to plasma-facing components (PFC) due to various plasma instabilities is still a major concern for the successful development of fusion energy and represents a significant research obstacle in the community. It is of great importance to fully understand the behavior and lifetime expectancy of PFC under both low energy cycles during normal events and highly energetic events as disruptions, Edge-Localized Modes (ELM), Vertical Displacement Events (VDE), and Run-away electron (RE). The consequences of these high energetic dumps with energy fluxes ranging from 10 MJ/m2 up to 200 MJ/m 2 applied in very short periods (0.1 to 5 ms) can be catastrophic both for safety and economic reasons. Those phenomena can cause a) large temperature increase in the target material b) consequent melting, evaporation and erosion losses due to the extremely high heat fluxes c) possible structural damage and permanent degradation of the entire bulk material with probable burnout of the coolant tubes; d) plasma contamination, transport of target material into the chamber far from where it was originally picked. The modeling of off-normal events such as Disruptions and ELMs requires the simultaneous solution of three main problems along time: a) the heat transfer in the plasma facing component b) the interaction of the produced vapor from the surface with the incoming plasma particles c) the transport of the radiation produced in the vapor-plasma cloud. In addition the moving boundaries problem has to be considered and solved at the material surface. Considering the carbon divertor as target, the moving boundaries are two since for the given conditions, carbon doesn't melt: the plasma front and the moving eroded material surface. The current solution methods for this problem use finite differences and moving coordinates system based on the Crank-Nicholson method and Alternating Directions Implicit Method (ADI). Currently Particle-In-Cell (PIC) methods are widely used for solving complex dynamics problems involving distorted plasma hydrodynamic problems and plasma physics. The PIC method solves the hydrodynamic equations solving all field equations tracking at the same time "sample particles" or pseudo-particles (representative of the much more numerous real ones) as the move under the influence of diffusion or magnetic force. The superior behavior of the PIC techniques over the more classical Lagrangian finite difference methods stands in the fact that detailed information about the particles are available at all times as well as mass and momentum transport values are constantly provided. This allows with a relative small number of particles to well describe the behavior of plasma even in presence of highly distorted flows without losing accuracy. The radiation transport equation is solved at each time step calculating for each cell the opacity and emissivity coefficients. Photon radiation continuum and line fluxes are also calculated per the entire domain and provide useful information for the entire energetic calculation of the system which in the end provides the total values of erosion and lifetime of the target material. In this thesis, a new code named HEIGHTS-PIC code has been created and modified using a new approach of the PIC technique to solve the three physics problems involved integrating each of them as a continuum providing insight on the plasma behavior, evolution along time and physical understanding of the very complex phenomena taking place. The results produced with the models are compared with the well-known and benchmarked HEIGHTS package and also with existing experimental results especially produced in Russia at the TRINITI facility. Comparisons with LASER experiments are also discussed.

On newly and recently recorded species of the genus Lema Fabricius (Coleoptera, Chrysomelidae, Criocerinae) from Taiwan

PubMed Central

Lee, Chi-Feng; Matsumura, Yoko

2013-01-01

Abstract New records of four species (Lema lacertosa Lacordaire, 1845, Lema diversipes Pic, 1921, Lema cyanella (Linnaeus, 1758), Lema trivittata trivittata Say, 1824 and additional information on one recently recorded species (Lema solani Fabricius, 1798) are reported for Taiwan. Lema diversipes Pic, 1921 is removed from synonymy with Lema lacertosa Lacordaire, 1845; both species are redescribed. A lectotype is designated for Lema phungi Pic, 1924. The synonymies of Lema phungi Pic, 1924 and Lema jeanvoinei Pic, 1932 with Lema lacertosa Lacordaire, 1845 are supported. A revised key to the known species in Taiwan is provided. PMID:23653513

Fully implicit Particle-in-cell algorithms for multiscale plasma simulation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chacon, Luis

The outline of the paper is as follows: Particle-in-cell (PIC) methods for fully ionized collisionless plasmas, explicit vs. implicit PIC, 1D ES implicit PIC (charge and energy conservation, moment-based acceleration), and generalization to Multi-D EM PIC: Vlasov-Darwin model (review and motivation for Darwin model, conservation properties (energy, charge, and canonical momenta), and numerical benchmarks). The author demonstrates a fully implicit, fully nonlinear, multidimensional PIC formulation that features exact local charge conservation (via a novel particle mover strategy), exact global energy conservation (no particle self-heating or self-cooling), adaptive particle orbit integrator to control errors in momentum conservation, and canonical momenta (EM-PICmore » only, reduced dimensionality). The approach is free of numerical instabilities: ω peΔt >> 1, and Δx >> λ D. It requires many fewer dofs (vs. explicit PIC) for comparable accuracy in challenging problems. Significant CPU gains (vs explicit PIC) have been demonstrated. The method has much potential for efficiency gains vs. explicit in long-time-scale applications. Moment-based acceleration is effective in minimizing N FE, leading to an optimal algorithm.« less

OSIRIS-REx Touch-And-Go (TAG) Navigation Performance

NASA Technical Reports Server (NTRS)

Berry, Kevin; Antreasian, Peter; Moreau, Michael C.; May, Alex; Sutter, Brian

2015-01-01

The Origins Spectral Interpretation Resource identification Security Regolith Explorer (OSIRIS-REx) mission is a NASA New Frontiers mission launching in 2016 to rendezvous with the near-Earth asteroid (101955) Bennu in late 2018. Following an extensive campaign of proximity operations activities to characterize the properties of Bennu and select a suitable sample site, OSIRIES-REx will fly a Touch-And-Go (TAG) trajectory to the asteroid's surface to obtain a regolith sample. The paper summarizes the mission design of the TAG sequence, the propulsive required to achieve the trajectory, and the sequence of events leading up to the TAG event. The paper will summarize the Monte-Carlo simulation of the TAG sequence and present analysis results that demonstrate the ability to conduct the TAG within 25 meters of the selected sample site and +-2 cms of the targeted contact velocity. The paper will describe some of the challenges associated with conducting precision navigation operations and ultimately contacting a very small asteroid.

OSIRI-REx Touch and Go (TAG) Navigation Performance

NASA Technical Reports Server (NTRS)

Berry, Kevin; Antreasian, Peter; Moreau, Michael C.; May, Alex; Sutter, Brian

2015-01-01

The Origins Spectral Interpretation Resource Identification Security Regolith Explorer (OSIRIS-REx) mission is a NASA New Frontiers mission launching in 2016 to rendezvous with the near-Earth asteroid (101955) Bennu in late 2018. Following an extensive campaign of proximity operations activities to characterize the properties of Bennu and select a suitable sample site, OSIRIS-REx will fly a Touch-And-Go (TAG) trajectory to the asteroid's surface to obtain a regolith sample. The paper summarizes the mission design of the TAG sequence, the propulsive maneuvers required to achieve the trajectory, and the sequence of events leading up to the TAG event. The paper also summarizes the Monte-Carlo simulation of the TAG sequence and presents analysis results that demonstrate the ability to conduct the TAG within 25 meters of the selected sample site and 2 cm/s of the targeted contact velocity. The paper describes some of the challenges associated with conducting precision navigation operations and ultimately contacting a very small asteroid.

Lessons Learned from Preparing OSIRIS-REx Spectral Analog Samples for Bennu

NASA Technical Reports Server (NTRS)

Schrader, D. L.; McCoy, T. J.; Cody, G. D.; King, A. J.; Schofield, P. F.; Russell, S. S.; Connolly, H. C., Jr.; Keller, L. P.; Donaldson Hanna, K.; Bowles, N.;

Extreme Scale Plasma Turbulence Simulations on Top Supercomputers Worldwide

DOE PAGES

Tang, William; Wang, Bei; Ethier, Stephane; ...

2016-11-01

The goal of the extreme scale plasma turbulence studies described in this paper is to expedite the delivery of reliable predictions on confinement physics in large magnetic fusion systems by using world-class supercomputers to carry out simulations with unprecedented resolution and temporal duration. This has involved architecture-dependent optimizations of performance scaling and addressing code portability and energy issues, with the metrics for multi-platform comparisons being 'time-to-solution' and 'energy-to-solution'. Realistic results addressing how confinement losses caused by plasma turbulence scale from present-day devices to the much larger $25 billion international ITER fusion facility have been enabled by innovative advances in themore » GTC-P code including (i) implementation of one-sided communication from MPI 3.0 standard; (ii) creative optimization techniques on Xeon Phi processors; and (iii) development of a novel performance model for the key kernels of the PIC code. Our results show that modeling data movement is sufficient to predict performance on modern supercomputer platforms.« less

Simulations of the interaction of intense petawatt laser pulses with dense Z-pinch plasmas : final report LDRD 39670.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Welch, Dale Robert; MacFarlane, Joseph John; Mehlhorn, Thomas Alan

We have studied the feasibility of using the 3D fully electromagnetic implicit hybrid particle code LSP (Large Scale Plasma) to study laser plasma interactions with dense, compressed plasmas like those created with Z, and which might be created with the planned ZR. We have determined that with the proper additional physics and numerical algorithms developed during the LDRD period, LSP was transformed into a unique platform for studying such interactions. Its uniqueness stems from its ability to consider realistic compressed densities and low initial target temperatures (if required), an ability that conventional PIC codes do not possess. Through several testmore » cases, validations, and applications to next generation machines described in this report, we have established the suitability of the code to look at fast ignition issues for ZR, as well as other high-density laser plasma interaction problems relevant to the HEDP program at Sandia (e.g. backlighting).« less

AMBER: a PIC slice code for DARHT

NASA Astrophysics Data System (ADS)

Vay, Jean-Luc; Fawley, William

1999-11-01

The accelerator for the second axis of the Dual Axis Radiographic Hydrodynamic Test (DARHT) facility will produce a 4-kA, 20-MeV, 2-μ s output electron beam with a design goal of less than 1000 π mm-mrad normalized transverse emittance and less than 0.5-mm beam centroid motion. In order to study the beam dynamics throughout the accelerator, we have developed a slice Particle-In-Cell code named AMBER, in which the beam is modeled as a time-steady flow, subject to self, as well as external, electrostatic and magnetostatic fields. The code follows the evolution of a slice of the beam as it propagates through the DARHT accelerator lattice, modeled as an assembly of pipes, solenoids and gaps. In particular, we have paid careful attention to non-paraxial phenomena that can contribute to nonlinear forces and possible emittance growth. We will present the model and the numerical techniques implemented, as well as some test cases and some preliminary results obtained when studying emittance growth during the beam propagation.

Measuring Stability and Security in Iraq

DTIC Science & Technology

2008-12-01

majority of the country. On September 1, 2008, Anbar Province, once an AQI stronghold, transferred to Provincial Iraqi Control ( PIC ). With the...transfer of Babil and Wasit Provinces to PIC in October 2008, the ISF is now in charge of security operations in the majority of Iraq’s 18 provinces... PIC ). Security responsibility for Babil Province was handed over to the GoI on October 23, 2008, and Wasit Province transitioned to PIC on October

Intracellular pressure is a motive force for cell motion in Amoeba proteus.

PubMed

Yanai, M; Kenyon, C M; Butler, J P; Macklem, P T; Kelly, S M

1996-01-01

The cortical filament layer of free-living amoebae contains concentrated actomyosin, suggesting that it can contract and produce an internal hydrostatic pressure. We report here on direct and dynamic intracellular pressure (P(ic)) measurements in Amoeba proteus made using the servo-null technique. In resting apolar A. proteus, P(ic) increased while the cells remained immobile and at apparently constant volume. P(ic) then decreased approximately coincident with pseudopod formation. There was a positive correlation between P(ic) at the onset of movement and the rate of pseudopod formation. These results are the first direct evidence that hydrostatic pressure may be a motive force for cell motion. We postulate that contractile elements in the amoeba's cortical layer contract and increase P(ic) and that this P(ic) is utilized to overcome the viscous flow resistance of the intracellular contents during pseudopod formation.

Particle-in-cell simulations of Earth-like magnetosphere during a magnetic field reversal

NASA Astrophysics Data System (ADS)

Barbosa, M. V. G.; Alves, M. V.; Vieira, L. E. A.; Schmitz, R. G.

2017-12-01

The geologic record shows that hundreds of pole reversals have occurred throughout Earth's history. The mean interval between the poles reversals is roughly 200 to 300 thousand years and the last reversal occurred around 780 thousand years ago. Pole reversal is a slow process, during which the strength of the magnetic field decreases, become more complex, with the appearance of more than two poles for some time and then the field strength increases, changing polarity. Along the process, the magnetic field configuration changes, leaving the Earth-like planet vulnerable to the harmful effects of the Sun. Understanding what happens with the magnetosphere during these pole reversals is an open topic of investigation. Only recently PIC codes are used to modeling magnetospheres. Here we use the particle code iPIC3D [Markidis et al, Mathematics and Computers in Simulation, 2010] to simulate an Earth-like magnetosphere at three different times along the pole reversal process. The code was modified, so the Earth-like magnetic field is generated using an expansion in spherical harmonics with the Gauss coefficients given by a MHD simulation of the Earth's core [Glatzmaier et al, Nature, 1995; 1999; private communication to L.E.A.V.]. Simulations show the qualitative behavior of the magnetosphere, such as the current structures. Only the planet magnetic field was changed in the runs. The solar wind is the same for all runs. Preliminary results show the formation of the Chapman-Ferraro current in the front of the magnetosphere in all the cases. Run for the middle of the reversal process, the low intensity magnetic field and its asymmetrical configuration the current structure changes and the presence of multiple poles can be observed. In all simulations, a structure similar to the radiation belts was found. Simulations of more severe solar wind conditions are necessary to determine the real impact of the reversal in the magnetosphere.

NASA Curation Preparation for Ryugu Sample Returned by JAXA's Hayabusa2 Mission

NASA Technical Reports Server (NTRS)

Nakamura-Messenger, Keiko; Righter, Kevin; Snead, Christopher J.; McCubbin, Francis M.; Pace, Lisa F.; Zeigler, Ryan A.; Evans, Cindy

2017-01-01

The NASA OSIRIS-REx and JAXA Hayabusa2 missions to near-Earth asteroids Bennu and Ryugu share similar mission goals of understanding the origins of primitive, organic-rich asteroids. Under an agreement between JAXA and NASA, there is an on-going and productive collaboration between science teams of Hayabusa2 and OSIRIS-REx missions. Under this agreement, a portion of each of the returned sample masses will be exchanged between the agencies and the scientific results of their study will be shared. NASA’s portion of the returned Hayabusa2 sample, consisting of 10% of the returned mass, will be jointly separated by NASA and JAXA. The sample will be legally and physically transferred to NASA’s dedicated Hayabusa2 curation facility at Johnson Space Center (JSC) no later than one year after the return of the Hayabusa2 sample to Earth (December 2020). The JSC Hayabusa2 curation cleanroom facility design has now been completed. In the same manner, JAXA will receive 0.5% of the total returned OSIRIS-REx sample (minimum required sample to return 60 g, maximum sample return capacity of 2 kg) from the rest of the specimen. No later than one year after the return of the OSIRIS-REx sample to Earth (September 2023), legal, physical, and permanent custody of this sample subset will be transferred to JAXA, and the sample subset will be brought to JAXA’s Extraterrestrial Sample Curation Center (ESCuC) at Institute of Space and Astronautical Science, Sagamihara City Japan.

Influence of picolinic acid on seizure susceptibility in mice.

PubMed

Cioczek-Czuczwar, Anna; Czuczwar, Piotr; Turski, Waldemar Andrzej; Parada-Turska, Jolanta

2017-02-01

The mechanism of drug resistance in epilepsy remains unknown. Picolinic acid (PIC) is an endogenous metabolite of the kynurenine pathway and a chelating agent added to dietary supplements. Both inhibitory and excitatory properties of PIC were reported. The aim of this study was to determine the influence of exogenously applied PIC upon the electroconvulsive threshold and the activity of chemical convulsants in eight models of epilepsy in mice. All experiments were performed on adult male Swiss albino mice. Electroconvulsions were induced through ear clip electrodes. The electroconvulsive threshold (current strength necessary to induce tonic seizures in 50% of the tested group - CS 50 ) was estimated for control animals and animals pretreated with PIC. To determine the possible convulsant activity of PIC, it was administered subcutaneously or intracerebroventricularly in increasing doses to calculate the CD 50 values (doses of convulsants necessary to produce seizures in 50% of the animals). Chemical convulsions were induced by challenging the animals with increasing doses of convulsant to calculate the CD 50 values. The following convulsants were used: 4-aminopyridine, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid, bicuculline, N-methyl-d-aspartate, nicotine, pentylenetrazole, pilocarpine hydrochloride and strychnine nitrate. PIC significantly decreased the electroconvulsive threshold and, after intracerebroventricular injection, but not subcutaneous, produced convulsions. Of the studied convulsants, only the activity of pilocarpine hydrochloride was significantly enhanced by PIC. PIC enhances seizure activity and potentially may play a role in the pathogenesis of drug resistant epilepsy. Future studies should focus on the interactions between PIC and antiepileptic drugs. Copyright © 2016. Published by Elsevier Urban & Partner Sp. z o.o.

Betatron x-ray radiation in the self-modulated wakefield acceleration regime (Conference Presentation)

NASA Astrophysics Data System (ADS)

Albert, Felicie

2017-05-01

Betatron x-ray radiation, driven by electrons from laser-wakefield acceleration, has unique properties to probe high energy density (HED) plasmas and warm dense matter. Betatron radiation is produced when relativistic electrons oscillate in the plasma wake of a laser pulse. Its properties are similar to those of synchrotron radiation, with a 1000 fold shorter pulse. This presentation will focus on the experimental challenges and results related to the development of betatron radiation in the self modulated regime of laser wakefield acceleration. We observed multi keV Betatron x-rays from a self-modulated laser wakefield accelerator. The experiment was performed at the Jupiter Laser Facility, LLNL, by focusing the Titan short pulse beam (4-150 J, 1 ps) onto the edge of a Helium gas jet at electronic densities around 1019 cm-3. For the first time on this laser system, we used a long focal length optic, which produced a laser normalized potential a0 in the range 1-3. Under these conditions, electrons are accelerated by the plasma wave created in the wake of the light pulse. As a result, intense Raman satellites, which measured shifts depend on the electron plasma density, were observed on the laser spectrum transmitted through the target. Electrons with energies up to 200 MeV, as well as Betatron x-rays with critical energies around 20 keV, were measured. OSIRIS 2D PIC simulations confirm that the electrons gain energy both from the plasma wave and from their interaction with the laser field.

Integrated Work Management: PIC, Course 31884

DOE Office of Scientific and Technical Information (OSTI.GOV)

Simpson, Lewis Edward

The person-in-charge (PIC) plays a key role in the integrated work management (IWM) process at Los Alamos National Laboratory (LANL, or the Laboratory) because the PIC is assigned responsibility and authority by the responsible line manager (RLM) for the overall validation, coordination, release, execution, and closeout of a work activity in accordance with IWM. This course, Integrated Work Management: PIC (Course 31884), describes the PIC’s IWM roles and responsibilities. This course also discusses IWM requirements that the PIC must meet. For a general overview of the IWM process, see self-study Course 31881, Integrated Work Management: Overview. For instruction on themore » preparer’s role, see self-study Course 31883, Integrated Work Management: Preparer.« less

PIC code modeling of spacecraft charging potential during electron beam injection into a background of neutral gas and plasma, part 1

NASA Technical Reports Server (NTRS)

Koga, J. K.; Lin, C. S.; Winglee, R. M.

1989-01-01

Injections of nonrelativistic electron beams from an isolated equipotential conductor into a uniform background of plasma and neutral gas were simulated using a 2-D electrostatic particle code. The ionization effects on spacecraft charging are examined by including interactions of electrons with neutral gas. The simulations show that the conductor charging potential decreases with increasing neutral background density due to the production of secondary electrons near the conductor surface. In the spacecraft wake, the background electrons accelerated towards the charged spacecraft produce an enhancement of secondary electrons and ions. Simulations run for longer times indicate that the spacecraft potential is further reduced and short wavelength beam-plasma oscillations appear. The results are applied to explain the spacecraft charging potential measured during the SEPAC experiments from Spacelab 1.

Molecular Dynamic Studies of Particle Wake Potentials in Plasmas

NASA Astrophysics Data System (ADS)

Ellis, Ian; Graziani, Frank; Glosli, James; Strozzi, David; Surh, Michael; Richards, David; Decyk, Viktor; Mori, Warren

2010-11-01

Fast Ignition studies require a detailed understanding of electron scattering, stopping, and energy deposition in plasmas with variable values for the number of particles within a Debye sphere. Presently there is disagreement in the literature concerning the proper description of these processes. Developing and validating proper descriptions requires studying the processes using first-principle electrostatic simulations and possibly including magnetic fields. We are using the particle-particle particle-mesh (P^3M) code ddcMD to perform these simulations. As a starting point in our study, we examined the wake of a particle passing through a plasma. In this poster, we compare the wake observed in 3D ddcMD simulations with that predicted by Vlasov theory and those observed in the electrostatic PIC code BEPS where the cell size was reduced to .03λD.

Bunch modulation in LWFA blowout regime

NASA Astrophysics Data System (ADS)

Vyskočil, Jiří; Klimo, Ondřej; Vieira, Jorge; Korn, Georg

2015-05-01

Laser wakefield acceleration (LWFA) is able to produce high quality electron bunches interesting for many applications ranging from coherent light sources to high energy physics. The blow-out regime of LWFA provides excellent accelerating structure able to maintain small transverse emittance and energy spread of the accelerating electron beam if combined with localised injection. A modulation of the back of a self-injected electron bunch in the blowout regime of Laser Wakefield Acceleration appears 3D Particle-in-Cell simulations with the code OSIRIS. The shape of the modulation is connected to the polarization of the driving laser pulse, although the wavelength of the modulation is longer than that of the pulse. Nevertheless a circularly polarized laser pulse leads to a corkscrew-like modulation, while in the case of linear polarization, the modulation lies in the polarization plane.

Effects of chromium picolinate on glucose uptake in insulin-resistant 3T3-L1 adipocytes involve activation of p38 MAPK.

PubMed

Wang, Yi-qun; Yao, Ming-hui

2009-12-01

Chromium picolinate (CrPic) has been discovered as a supplemental or alternative medication for type 2 diabetes, but its mechanism of action is not well understood. The purpose of this study was to explore the possible anti-diabetic mechanisms of CrPic in insulin-resistant 3T3-L1 adipocytes; the insulin resistance was induced by treatment with high glucose and insulin for 24 h. The effects of CrPic on glucose metabolism and the glucose uptake-inducing activity of CrPic were investigated. Meanwhile, the effects of CrPic on glucose transporter 4 (GLUT4) translocation were visualized by immonofluorescence microscopy. In addition, its effects on insulin signaling pathways and mitogen-activated protein kinase (MAPK) signaling cascades were assessed by immunoblotting analysis and real-time PCR. The results showed that CrPic induced glucose metabolism and uptake, as well as GLUT4 translocation to plasma membrane (PM) in both control and insulin-resistant 3T3-L1 adipocytes without any changes in insulin receptor beta (IR-beta), protein kinase B (AKt), c-Cbl, extracellular signal-regulated kinase (ERK), c-Jun phosphorylation and c-Cbl-associated protein (CAP) mRNA levels. Interestingly, CrPic was able to increase the basal and insulin-stimulated levels of p38 MAPK activation in the control and insulin-resistant cells. Pretreatment with the specific p38 MAPK inhibitor SB203580 partially inhibited the CrPic-induced glucose transport, but CrPic-activated translocation of GLUT4 was not inhibited by SB203580. This study provides an experimental evidence of the effects of CrPic on glucose uptake through the activation of p38 MAPK and it is independent of the effect on GLUT4 translocation. The findings also suggest exciting new insights into the role of p38 MAPK in glucose uptake and GLUT4 translocation.

Assessment of the anticonvulsant potency of various benzylamide derivatives in the mouse maximal electroshock-induced seizure threshold model.

PubMed

Świąder, Mariusz J; Paruszewski, Ryszard; Łuszczki, Jarogniew J

2016-04-01

The aim of this study was to assess the anticonvulsant potency of 6 various benzylamide derivatives [i.e., nicotinic acid benzylamide (Nic-BZA), picolinic acid 2-fluoro-benzylamide (2F-Pic-BZA), picolinic acid benzylamide (Pic-BZA), (RS)-methyl-alanine-benzylamide (Me-Ala-BZA), isonicotinic acid benzylamide (Iso-Nic-BZA), and (R)-N-methyl-proline-benzylamide (Me-Pro-BZA)] in the threshold for maximal electroshock (MEST)-induced seizures in mice. Electroconvulsions (seizure activity) were produced in mice by means of a current (sine-wave, 50Hz, 500V, strength from 4 to 18mA, ear-clip electrodes, 0.2-s stimulus duration, tonic hindlimb extension taken as the endpoint). Nic-BZA, 2F-Pic-BZA, Pic-BZA, Me-Ala-BZA, Iso-Nic-BZA, and Me-Pro-BZA administered systemically (ip) in a dose-dependent manner increase the threshold for maximal electroconvulsions in mice. Linear regression analysis of Nic-BZA, 2F-Pic-BZA, Pic-BZA, MeAla-BZA, IsoNic-BZA, and Me-Pro-BZA doses and their corresponding threshold increases allowed determining threshold increasing doses by 20% (TID20 values) that elevate the threshold in drug-treated animals over the threshold in control animals. The experimentally derived TID20 values in the MEST test for Nic-BZA, 2F-Pic-BZA, Pic-BZA, Me-Ala-BZA, Iso-Nic-BZA, and Me-Pro-BZA were 7.45mg/kg, 7.72mg/kg, 8.74mg/kg, 15.11mg/kg, 21.95mg/kg and 28.06mg/kg, respectively. The studied benzylamide derivatives can be arranged with respect to their anticonvulsant potency in the MEST test as follows: Nic-BZA>2F-Pic-BZA>Pic-BZA>Me-Ala-BZA>Iso-Nic-BZA>Me-Pro-BZA. Copyright © 2015 Institute of Pharmacology, Polish Academy of Sciences. Published by Elsevier Urban & Partner Sp. z o.o. All rights reserved.

Clinical studies on chromium picolinate supplementation in diabetes mellitus--a review.

PubMed

Broadhurst, C Leigh; Domenico, Philip

2006-12-01

Chromium (Cr) picolinate (CrPic) is a widely used nutritional supplement for optimal insulin function. A relationship among Cr status, diabetes, and associated pathologies has been established. Virtually all trials using CrPic supplementation for subjects with diabetes have demonstrated beneficial effects. Thirteen of 15 clinical studies (including 11 randomized, controlled studies) involving a total of 1,690 subjects (1,505 in CrPic group) reported significant improvement in at least one outcome of glycemic control. All 15 studies showed salutary effects in at least one parameter of diabetes management, including dyslipidemia. Positive outcomes from CrPic supplementation included reduced blood glucose, insulin, cholesterol, and triglyceride levels and reduced requirements for hypoglycemic medication. The greater bioavailability of CrPic compared with other forms of Cr (e.g., niacin-bound Cr or CrCl(3)) may explain its comparatively superior efficacy in glycemic and lipidemic control. The pooled data from studies using CrPic supplementation for type 2 diabetes mellitus subjects show substantial reductions in hyperglycemia and hyperinsulinemia, which equate to a reduced risk for disease complications. Collectively, the data support the safety and therapeutic value of CrPic for the management of cholesterolemia and hyperglycemia in subjects with diabetes.

The Nature of C Asteroid Regolith from Meteorite Observations

NASA Technical Reports Server (NTRS)

Zolensky, M.; Mikouchi, T.; Hagiya, K.; Ohsumi, K.; Komatsu, M.; Jenniskens, P.; Le, L.; Yin, Q.-Z; Kebukawa, Y.; Fries, M.

2013-01-01

Regolith from C (and related) asteroid bodies are a focus of the current missions Dawn at Ceres, Hayabusa 2 and OSIRIS REx. An asteroid as large as Ceres is expected to be covered by a mature regolith, and as Hayabusa demonstrated, flat and therefore engineeringly-safe ponded deposits will probably be the sampling sites for both Hayabusa 2 and OSIRIS REx. Here we examine what we have learned about the mineralogy of fine-grained asteroid regolith from recent meteorite studies and the examination of the samples harvested from asteroid Itokawa by Hayabusa.

OSIRIS-REx Rollout for Launch

NASA Image and Video Library

2016-09-07

The United Launch Alliance Atlas V rocket arrives at Space Launch Complex 41 at Cape Canaveral Air Force Station in Florida. The launch vehicle will boost NASA’s Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer, or OSIRIS-REx spacecraft. This will be the first U.S. mission to sample an asteroid, retrieve at least two ounces of surface material and return it to Earth for study. The asteroid, Bennu, may hold clues to the origin of the solar system and the source of water and organic molecules found on Earth.

OSIRIS-REx Rollout for Launch

NASA Image and Video Library

2016-09-07

After leaving the Vertical Integration Facility, a United Launch Alliance Atlas V rocket arrives at Space Launch Complex 41 at Cape Canaveral Air Force Station in Florida. The launch vehicle will boost NASA’s Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer, or OSIRIS-REx spacecraft. This will be the first U.S. mission to sample an asteroid, retrieve at least two ounces of surface material and return it to Earth for study. The asteroid, Bennu, may hold clues to the origin of the solar system and the source of water and organic molecules found on Earth.

OSIRIS-REx Rollout for Launch

NASA Image and Video Library

2016-09-07

The United Launch Alliance Atlas V rocket arrives at Space Launch Complex 41 at Cape Canaveral Air Force Station in Florida. The launch vehicle will boost NASA’s Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer, or OSIRIS-REx spacecraft. This will be the first U.S. mission to sample an asteroid, retrieve at least two ounces of surface material and return it to Earth for study. The asteroid, Bennu, may hold clues to the origin of the solar system and the source of water and organic molecules found on Earth. Photo credit: NASA/Kim Shiflett

Effects of dietary chromium picolinate and peppermint essential oil on growth performance and blood biochemical parameters of broiler chicks reared under heat stress conditions

NASA Astrophysics Data System (ADS)

Akbari, Mohsen; Torki, Mehran

2014-08-01

A study was conducted using 240 female day-old broiler chicks to evaluate the effects of dietary chromium picolinate (CrPic), peppermint essential oil (P.mint), or their combination on growth performance and blood biochemical parameters of female broiler chicks raised under heat stress conditions (HS, 23.9 to 38 °C cycling). Average daily gain (ADG), average daily feed intake (ADFI), and feed conversion ratio (FCR) were obtained from 1 to 42 days of age. Furthermore, at the end of the experiment (day 42), birds were bled to determine some blood biochemical parameters and weighed for final body weight (BW). ADFI, ADG, and BW were not influenced significantly by dietary CrPic and P.mint ( P > 0.05). A significant interaction between dietary CrPic and P.mint on FCR ( P = 0.012) was detected. FCR significantly decreased in chicks fed the diet including both CrPic and P.mint compared with the CrPic group. Significant interaction between dietary P.mint and CrPic on serum concentrations of triglycerides, glucose, and albumin were observed ( P < 0.05), but the other measured blood biochemical parameters were not statistically affected by dietary treatments ( P > 0.05). The serum concentrations of glucose, triglycerides were decreased ( P < 0.05) in broilers fed the diet including both CrPic and P.mint. Plasma chromium (Cr) content increased significantly ( P < 0.05) in birds fed the CrPic-included diet compared with the control group ( P < 0.05). From the results of the present experiment it can be concluded that dietary supplementation with combined P.mint and CrPic could have beneficial effects on some blood biochemical parameters of female chicks reared under heat stress conditions.

Effects of dietary chromium picolinate and peppermint essential oil on growth performance and blood biochemical parameters of broiler chicks reared under heat stress conditions.

PubMed

Akbari, Mohsen; Torki, Mehran

2014-08-01

A study was conducted using 240 female day-old broiler chicks to evaluate the effects of dietary chromium picolinate (CrPic), peppermint essential oil (P.mint), or their combination on growth performance and blood biochemical parameters of female broiler chicks raised under heat stress conditions (HS, 23.9 to 38 °C cycling). Average daily gain (ADG), average daily feed intake (ADFI), and feed conversion ratio (FCR) were obtained from 1 to 42 days of age. Furthermore, at the end of the experiment (day 42), birds were bled to determine some blood biochemical parameters and weighed for final body weight (BW). ADFI, ADG, and BW were not influenced significantly by dietary CrPic and P.mint (P>0.05). A significant interaction between dietary CrPic and P.mint on FCR (P=0.012) was detected. FCR significantly decreased in chicks fed the diet including both CrPic and P.mint compared with the CrPic group. Significant interaction between dietary P.mint and CrPic on serum concentrations of triglycerides, glucose, and albumin were observed (P<0.05), but the other measured blood biochemical parameters were not statistically affected by dietary treatments (P>0.05). The serum concentrations of glucose, triglycerides were decreased (P<0.05) in broilers fed the diet including both CrPic and P.mint. Plasma chromium (Cr) content increased significantly (P<0.05) in birds fed the CrPic-included diet compared with the control group (P<0.05). From the results of the present experiment it can be concluded that dietary supplementation with combined P.mint and CrPic could have beneficial effects on some blood biochemical parameters of female chicks reared under heat stress conditions.

Neolinoptes gen. n., a replacement name for the net-winged beetle genus Linoptes Gorham, 1884 and a new species of Lycomorphon from Guyana (Coleoptera: Lycidae).

PubMed

Nascimento, Elynton Alves DO; Bocakova, Milada

2017-01-09

Neolinoptes gen. n. is erected to replace Linoptes Gorham, 1884, preoccupied by Linoptes Menge, 1854 (Arachnida: Araneae). Consequently, Neolinoptes imbrex (Gorham, 1884) comb. n., N. amazonicus (Pic, 1923) comb. n., N. atronotatus (Pic, 1922) comb. n., N. atripennis (Pic, 1932) comb. n. are proposed. Calocladon rubidum Gorham, 1884 is transferred to Neolinoptes. Lycomorphon iwokrama sp. n. is proposed as new to science and the genus is recorded from Guyana for the first time. Additionally, Falsocaenia irregularis var. germaini Pic, 1931 is elevated to species rank and past confusion on F. irregularis discussed. New data on geographical distribution of Falsocaenia paranana (Pic, 1922) are presented.

Massive parallel 3D PIC simulation of negative ion extraction

NASA Astrophysics Data System (ADS)

Revel, Adrien; Mochalskyy, Serhiy; Montellano, Ivar Mauricio; Wünderlich, Dirk; Fantz, Ursel; Minea, Tiberiu

2017-09-01

The 3D PIC-MCC code ONIX is dedicated to modeling Negative hydrogen/deuterium Ion (NI) extraction and co-extraction of electrons from radio-frequency driven, low pressure plasma sources. It provides valuable insight on the complex phenomena involved in the extraction process. In previous calculations, a mesh size larger than the Debye length was used, implying numerical electron heating. Important steps have been achieved in terms of computation performance and parallelization efficiency allowing successful massive parallel calculations (4096 cores), imperative to resolve the Debye length. In addition, the numerical algorithms have been improved in terms of grid treatment, i.e., the electric field near the complex geometry boundaries (plasma grid) is calculated more accurately. The revised model preserves the full 3D treatment, but can take advantage of a highly refined mesh. ONIX was used to investigate the role of the mesh size, the re-injection scheme for lost particles (extracted or wall absorbed), and the electron thermalization process on the calculated extracted current and plasma characteristics. It is demonstrated that all numerical schemes give the same NI current distribution for extracted ions. Concerning the electrons, the pair-injection technique is found well-adapted to simulate the sheath in front of the plasma grid.

Design and 3D simulation of a two-cavity wide-gap relativistic klystron amplifier with high power injection

NASA Astrophysics Data System (ADS)

Bai, Xianchen; Yang, Jianhua; Zhang, Jiande

2012-08-01

By using an electromagnetic particle-in-cell (PIC) code, an S-band two-cavity wide-gap klystron amplifier (WKA) loaded with washers/rods structure is designed and investigated for high power injection application. Influences of the washers/rods structure on the high frequency characteristics and the basic operation of the amplifier are presented. Generally, the rod structure has great impacts on the space-charge potential depression and the resonant frequency of the cavities. Nevertheless, if only the resonant frequency is tuned to the desired operation frequency, effects of the rod size on the basic operation of the amplifier are expected to be very weak. The 3-dimension (3-D) PIC simulation results show an output power of 0.98 GW corresponding to an efficiency of 33% for the WKA, with a 594 keV, 5 kA electron beam guided by an external magnetic field of 1.5 Tesla. Moreover, if a conductive plane is placed near the output gap, such as the electron collector, the beam potential energy can be further released, and the RF power can be increased to about 1.07 GW with the conversion efficiency of about 36%.

Direct Laser Acceleration in Laser Wakefield Accelerators

NASA Astrophysics Data System (ADS)

Shaw, J. L.; Froula, D. H.; Marsh, K. A.; Joshi, C.; Lemos, N.

2017-10-01

The direct laser acceleration (DLA) of electrons in a laser wakefield accelerator (LWFA) has been investigated. We show that when there is a significant overlap between the drive laser and the trapped electrons in a LWFA cavity, the accelerating electrons can gain energy from the DLA mechanism in addition to LWFA. The properties of the electron beams produced in a LWFA, where the electrons are injected by ionization injection, have been investigated using particle-in-cell (PIC) code simulations. Particle tracking was used to demonstrate the presence of DLA in LWFA. Further PIC simulations comparing LWFA with and without DLA show that the presence of DLA can lead to electron beams that have maximum energies that exceed the estimates given by the theory for the ideal blowout regime. The magnitude of the contribution of DLA to the energy gained by the electron was found to be on the order of the LWFA contribution. The presence of DLA in a LWFA can also lead to enhanced betatron oscillation amplitudes and increased divergence in the direction of the laser polarization. This material is based upon work supported by the Department of Energy National Nuclear Security Administration under Award Number DE-NA0001944.

Kinetic Approaches to Shear-Driven Magnetic Reconnection for Multi-Scale Modeling of CME Initiation

NASA Astrophysics Data System (ADS)

Black, C.; Antiochos, S. K.; DeVore, C.; Germaschewski, K.; Karpen, J. T.

2013-12-01

In the standard model for coronal mass ejections (CME) and/or solar flares, the free energy for the event resides in the strongly sheared magnetic field of a filament channel. The pre-eruption force balance, consisting of an upward force due to the magnetic pressure of the sheared field balanced by a downward tension due to overlying un-sheared field, is widely believed to be disrupted by magnetic reconnection. Therefore, understanding initiation of solar explosive phenomena requires a true multi-scale model of reconnection onset driven by the buildup of magnetic shear. While the application of magnetic-field shear is a trivial matter in MHD simulations, it is a significant challenge in a PIC code. The driver must be implemented in a self-consistent manner and with boundary conditions that avoid the generation of waves that destroy the applied shear. In this work, we describe drivers for 2.5D, aperiodic, PIC systems and discuss the implementation of driver-consistent boundary conditions that allow a net electric current to flow through the walls. Preliminary tests of these boundaries with a MHD equilibrium are shown. This work was supported, in part, by the NASA Living With a Star TR&T Program.

Electromagnetic particle-in-cell simulations of the solar wind interaction with lunar magnetic anomalies.

PubMed

Deca, J; Divin, A; Lapenta, G; Lembège, B; Markidis, S; Horányi, M

2014-04-18

We present the first three-dimensional fully kinetic and electromagnetic simulations of the solar wind interaction with lunar crustal magnetic anomalies (LMAs). Using the implicit particle-in-cell code iPic3D, we confirm that LMAs may indeed be strong enough to stand off the solar wind from directly impacting the lunar surface forming a mini-magnetosphere, as suggested by spacecraft observations and theory. In contrast to earlier magnetohydrodynamics and hybrid simulations, the fully kinetic nature of iPic3D allows us to investigate the space charge effects and in particular the electron dynamics dominating the near-surface lunar plasma environment. We describe for the first time the interaction of a dipole model centered just below the lunar surface under plasma conditions such that only the electron population is magnetized. The fully kinetic treatment identifies electromagnetic modes that alter the magnetic field at scales determined by the electron physics. Driven by strong pressure anisotropies, the mini-magnetosphere is unstable over time, leading to only temporal shielding of the surface underneath. Future human exploration as well as lunar science in general therefore hinges on a better understanding of LMAs.

MITHRA 1.0: A full-wave simulation tool for free electron lasers

NASA Astrophysics Data System (ADS)

Fallahi, Arya; Yahaghi, Alireza; Kärtner, Franz X.

2018-07-01

Free Electron Lasers (FELs) are a solution for providing intense, coherent and bright radiation in the hard X-ray regime. Due to the low wall-plug efficiency of FEL facilities, it is crucial and additionally very useful to develop complete and accurate simulation tools for better optimizing a FEL interaction. The highly sophisticated dynamics involved in a FEL process was the main obstacle hindering the development of general simulation tools for this problem. We present a numerical algorithm based on finite difference time domain/Particle in cell (FDTD/PIC) in a Lorentz boosted coordinate system which is able to fulfill a full-wave simulation of a FEL process. The developed software offers a suitable tool for the analysis of FEL interactions without considering any of the usual approximations. A coordinate transformation to bunch rest frame makes the very different length scales of bunch size, optical wavelengths and the undulator period transform to values with the same order. Consequently, FDTD/PIC simulations in conjunction with efficient parallelization techniques make the full-wave simulation feasible using the available computational resources. Several examples of free electron lasers are analyzed using the developed software, the results are benchmarked based on standard FEL codes and discussed in detail.

Dissipation and particle energization in moderate to low beta turbulent plasma via PIC simulations

NASA Astrophysics Data System (ADS)

Makwana, Kirit; Li, Hui; Guo, Fan; Li, Xiaocan

2017-05-01

We simulate decaying turbulence in electron-positron pair plasmas using a fully-kinetic particle-in-cell (PIC) code. We run two simulations with moderate-to-low plasma β (the ratio of thermal pressure to magnetic pressure). The energy decay rate is found to be similar in both cases. The perpendicular wave-number spectrum of magnetic energy shows a slope between {k}\\perp -1.3 and {k}\\perp -1.1, where the perpendicular (⊥) and parallel (∥) directions are defined with respect to the magnetic field. The particle kinetic energy distribution function shows the formation of a non-thermal feature in the case of lower plasma β, with a slope close to E-1. The correlation between thin turbulent current sheets and Ohmic heating by the dot product of electric field (E) and current density (J) is investigated. Heating by the parallel E∥ · J∥ term dominates the perpendicular E⊥ · J⊥ term. Regions of strong E∥ · J∥ are spatially well-correlated with regions of intense current sheets, which also appear correlated with regions of strong E∥ in the low β simulation, suggesting an important role of magnetic reconnection in the dissipation of low β plasma turbulence.

Particle-in-cell modeling for MJ scale dense plasma focus with varied anode shape

DOE Office of Scientific and Technical Information (OSTI.GOV)

Link, A., E-mail: link6@llnl.gov; Halvorson, C., E-mail: link6@llnl.gov; Schmidt, A.

2014-12-15

Megajoule scale dense plasma focus (DPF) Z-pinches with deuterium gas fill are compact devices capable of producing 10{sup 12} neutrons per shot but past predictive models of large-scale DPF have not included kinetic effects such as ion beam formation or anomalous resistivity. We report on progress of developing a predictive DPF model by extending our 2D axisymmetric collisional kinetic particle-in-cell (PIC) simulations from the 4 kJ, 200 kA LLNL DPF to 1 MJ, 2 MA Gemini DPF using the PIC code LSP. These new simulations incorporate electrodes, an external pulsed-power driver circuit, and model the plasma from insulator lift-off throughmore » the pinch phase. To accommodate the vast range of relevant spatial and temporal scales involved in the Gemini DPF within the available computational resources, the simulations were performed using a new hybrid fluid-to-kinetic model. This new approach allows single simulations to begin in an electron/ion fluid mode from insulator lift-off through the 5-6 μs run-down of the 50+ cm anode, then transition to a fully kinetic PIC description during the run-in phase, when the current sheath is 2-3 mm from the central axis of the anode. Simulations are advanced through the final pinch phase using an adaptive variable time-step to capture the fs and sub-mm scales of the kinetic instabilities involved in the ion beam formation and neutron production. Validation assessments are being performed using a variety of different anode shapes, comparing against experimental measurements of neutron yield, neutron anisotropy and ion beam production.« less

Assessment of Different Discrete Particle Methods Ability To Predict Gas-Particle Flow in a Small-Scale Fluidized Bed

DOE PAGES

Lu, Liqiang; Gopalan, Balaji; Benyahia, Sofiane

2017-06-21

Several discrete particle methods exist in the open literature to simulate fluidized bed systems, such as discrete element method (DEM), time driven hard sphere (TDHS), coarse-grained particle method (CGPM), coarse grained hard sphere (CGHS), and multi-phase particle-in-cell (MP-PIC). These different approaches usually solve the fluid phase in a Eulerian fixed frame of reference and the particle phase using the Lagrangian method. The first difference between these models lies in tracking either real particles or lumped parcels. The second difference is in the treatment of particle-particle interactions: by calculating collision forces (DEM and CGPM), using momentum conservation laws (TDHS and CGHS),more » or based on particle stress model (MP-PIC). These major model differences lead to a wide range of results accuracy and computation speed. However, these models have never been compared directly using the same experimental dataset. In this research, a small-scale fluidized bed is simulated with these methods using the same open-source code MFIX. The results indicate that modeling the particle-particle collision by TDHS increases the computation speed while maintaining good accuracy. Also, lumping few particles in a parcel increases the computation speed with little loss in accuracy. However, modeling particle-particle interactions with solids stress leads to a big loss in accuracy with a little increase in computation speed. The MP-PIC method predicts an unphysical particle-particle overlap, which results in incorrect voidage distribution and incorrect overall bed hydrodynamics. Based on this study, we recommend using the CGHS method for fluidized bed simulations due to its computational speed that rivals that of MPPIC while maintaining a much better accuracy.« less

Quality Management, Certification and Rating of Health Information on the Net with MedCERTAIN: Using a medPICS/RDF/XML metadata structure for implementing eHealth ethics and creating trust globally

PubMed Central

Eysenbach, Gunther; Yihune, Gabriel; Lampe, Kristian; Cross, Phil; Brickley, Dan

2000-01-01

MedCERTAIN (MedPICS Certification and Rating of Trustworthy Health Information on the Net, http://www.medcertain.org/) is a recently launched international project funded under the European Union's (EU) "Action Plan for safer use of the Internet". It provides a technical infrastructure and a conceptual basis for an international system of "quality seals", ratings and self-labelling of Internet health information, with the final aim to establish a global "trustmark" for networked health information. Digital "quality seals" are evaluative metadata (using standards such as PICS=Platform for Internet Content Selection, now being replaced by RDF/XML) assigned by trusted third-party raters. The project also enables and encourages self-labelling with descriptive metainformation by web authors. Together these measures will help consumers as well as professionals to identify high-quality information on the Internet. MedCERTAIN establishes a fully functional demonstrator for a self- and third-party rating system enabling consumers and professionals to filter harmful health information and to positively identify and select high quality information. We aim to provide a trustmark system which allows citizens to place greater confidence in networked information, to encourage health information providers to follow best practices guidelines such as the Washington eHealth Code of Ethics, to provide effective feedback and law enforcement channels to handle user complaints, and to stimulate medical societies to develop standard for patient information. The project further proposes and identifies standards for interoperability of rating and description services (such as libraries or national health portals) and fosters a worldwide collaboration to guide consumers to high-quality information on the web.

Assessment of Different Discrete Particle Methods Ability To Predict Gas-Particle Flow in a Small-Scale Fluidized Bed

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lu, Liqiang; Gopalan, Balaji; Benyahia, Sofiane

Several discrete particle methods exist in the open literature to simulate fluidized bed systems, such as discrete element method (DEM), time driven hard sphere (TDHS), coarse-grained particle method (CGPM), coarse grained hard sphere (CGHS), and multi-phase particle-in-cell (MP-PIC). These different approaches usually solve the fluid phase in a Eulerian fixed frame of reference and the particle phase using the Lagrangian method. The first difference between these models lies in tracking either real particles or lumped parcels. The second difference is in the treatment of particle-particle interactions: by calculating collision forces (DEM and CGPM), using momentum conservation laws (TDHS and CGHS),more » or based on particle stress model (MP-PIC). These major model differences lead to a wide range of results accuracy and computation speed. However, these models have never been compared directly using the same experimental dataset. In this research, a small-scale fluidized bed is simulated with these methods using the same open-source code MFIX. The results indicate that modeling the particle-particle collision by TDHS increases the computation speed while maintaining good accuracy. Also, lumping few particles in a parcel increases the computation speed with little loss in accuracy. However, modeling particle-particle interactions with solids stress leads to a big loss in accuracy with a little increase in computation speed. The MP-PIC method predicts an unphysical particle-particle overlap, which results in incorrect voidage distribution and incorrect overall bed hydrodynamics. Based on this study, we recommend using the CGHS method for fluidized bed simulations due to its computational speed that rivals that of MPPIC while maintaining a much better accuracy.« less

Simulation of transient effects in the heavy ion fusion injectors

NASA Astrophysics Data System (ADS)

Chen, Yu-Jiuan; Hewett, D. W.

1993-05-01

We have used the 2-D PIC code, GYMNOS, to study the transient behaviors in the Heavy Ion Fusion (HIF) injectors. GYMNOS simulations accurately provide the steady state Child-Langmuir current and the beam transient behavior within a planar diode. The simulations of the LBL HIF ESAC injector experiments agree well with the experimental data and EGUN steady state results. Simulations of the nominal HIF injectors have revealed the need to design the accelerating electrodes carefully to control the ion beam current, particularly the ion loss at the end of the bunch as the extraction voltage is reduced.

LLE review. Quarterly report, January 1994--March 1994, Volume 58

DOE Office of Scientific and Technical Information (OSTI.GOV)

Simon, A.

1994-07-01

This volume of the LLE Review, covering the period Jan - Mar 1994, contains articles on backlighting diagnostics; the effect of electron collisions on ion-acoustic waves and heat flow; using PIC code simulations for analysis of ultrashort laser pulses interacting with solid targets; creating a new instrument for characterizing thick cryogenic layers; and a description of a large-aperture ring amplifier for laser-fusion drivers. Three of these articles - backlighting diagnostics; characterizing thick cryogenic layers; and large-aperture ring amplifier - are directly related to the OMEGA Upgrade, now under construction. Separate abstracts have been prepared for articles from this report.

End-to-end plasma bubble PIC simulations on GPUs

NASA Astrophysics Data System (ADS)

Germaschewski, Kai; Fox, William; Matteucci, Jackson; Bhattacharjee, Amitava

2017-10-01

Accelerator technologies play a crucial role in eventually achieving exascale computing capabilities. The current and upcoming leadership machines at ORNL (Titan and Summit) employ Nvidia GPUs, which provide vast computational power but also need specifically adapted computational kernels to fully exploit them. In this work, we will show end-to-end particle-in-cell simulations of the formation, evolution and coalescence of laser-generated plasma bubbles. This work showcases the GPU capabilities of the PSC particle-in-cell code, which has been adapted for this problem to support particle injection, a heating operator and a collision operator on GPUs.

Two-way coupling of magnetohydrodynamic simulations with embedded particle-in-cell simulations

NASA Astrophysics Data System (ADS)

Makwana, K. D.; Keppens, R.; Lapenta, G.

2017-12-01

We describe a method for coupling an embedded domain in a magnetohydrodynamic (MHD) simulation with a particle-in-cell (PIC) method. In this two-way coupling we follow the work of Daldorff et al. (2014) [19] in which the PIC domain receives its initial and boundary conditions from MHD variables (MHD to PIC coupling) while the MHD simulation is updated based on the PIC variables (PIC to MHD coupling). This method can be useful for simulating large plasma systems, where kinetic effects captured by particle-in-cell simulations are localized but affect global dynamics. We describe the numerical implementation of this coupling, its time-stepping algorithm, and its parallelization strategy, emphasizing the novel aspects of it. We test the stability and energy/momentum conservation of this method by simulating a steady-state plasma. We test the dynamics of this coupling by propagating plasma waves through the embedded PIC domain. Coupling with MHD shows satisfactory results for the fast magnetosonic wave, but significant distortion for the circularly polarized Alfvén wave. Coupling with Hall-MHD shows excellent coupling for the whistler wave. We also apply this methodology to simulate a Geospace Environmental Modeling (GEM) challenge type of reconnection with the diffusion region simulated by PIC coupled to larger scales with MHD and Hall-MHD. In both these cases we see the expected signatures of kinetic reconnection in the PIC domain, implying that this method can be used for reconnection studies.

Searching for Short GRBs in Soft Gamma Rays with INTEGRAL/PICsIT

NASA Astrophysics Data System (ADS)

Rodi, James; Bazzano, Angela; Ubertini, Pietro; Natalucci, Lorenzo; Savchenko, V.; Kuulkers, E.; Ferrigno, Carlo; Bozzo, Enrico; Brandt, Soren; Chenevez, Jerome; Courvoisier, T. J.-L.; Diehl, R.; Domingo, A.; Hanlon, L.; Jourdain, E.; von Kienlin, A.; Laurent, P.; Lebrun, F.; Lutovinov, A.; Martin-Carrillo, A.; Mereghetti, S.; Roques, J.-P.; Sunyaev, R.

2018-01-01

With gravitational wave (GW) detections by the LIGO/Virgo collaboration over the past several years, there is heightened interest in gamma-ray bursts (GRBs), especially “short” GRBs (T90 <2s). The high-energy PICsIT detector (~0.2 – 10 MeV) on-board the INTErnational Gamma-Ray Astrophysics Laboratory (INTEGRAL) is able to observe sources out to approximately 70° off-axis, making it essentially a soft gamma-ray, all-sky monitor for impulsive events, such as SGRBs. Because SGRBs typically have hard spectra with peak energies of a few hundred keV, PICsIT with its ~ 3000 cm2 collecting area is able to provide spectral information about these sources at soft gamma-ray energies.We have begun a study of PICsIT data for faint SGRBs similar to the one associated with the binary neutron star (BNS) merger GW 170817, and also are preparing for future GW triggers by developing a real-time burst analysis for PICsIT. Searching the PICsIT data for significant excesses during ~30 min-long pointings containing times of SGRBs, we have been able to differentiate between SGRBs and spurious events. Also, this work allows us to assess what fraction of reported SGRBs have been detected by PICsIT, which can be used to provide an estimate of the number of GW BNS events seen by PICsIT during the next LIGO/Virgo observing run starting in Fall 2018.

Thermal Assessment of Sunlight Impinging on OSIRIS-REx OCAMS PolyCam, OTES, and IMU-Sunshade MLI Blankets in Flight

NASA Technical Reports Server (NTRS)

Choi, Michael K.

2017-01-01

The NASA Origins, Spectral Interpretation, Resource Identification, Security, Regolith Explorer (OSIRIS-REx) spacecraft was successfully launched into orbit on September 8, 2016. It is traveling to a near-Earth asteroid (101955) Bennu, study it in detail, and bring back a pristine sample to Earth for scientific analyses. At the Outbound Cruise nominal spacecraft attitude, with Sun on +X, sunlight impinges on the OSIRIS-REx camera suite (OCAMS) PolyCam sunshade multilayer insulation (MLI) with microporous black polytetrafluoroethylene (PTFE), a portion of the PolyCam optics support tube (MLI with germanium black Kapton (GBK)), a portion of the OSIRIS-REx Thermal Emission Spectrometer (OTES) sunshade (MLI with GBK), the Inertia Measurement Unit (IMU) sunshade (MLI with GBK), and the OSIRIS-REx Laser Altimeter (OLA) sunshade (MLI with GBK). Sunlight is reflected or scattered by the above MLIs to the other components on the forward (+Z) deck. It illuminates the forward deck. A detailed thermal assessment on the solar impingement has been performed for the Proximity Ops at the asteroid, Touch-and-Go (TAG) sample acquisition, and Return Cruise mission phases.The OSIRIS-REx Outbound Cruise flight temperature telemetry and USM_3_DPC_0_CURRENT flight currenttelemetry data have been analyzed. It is evident that at the nominal Outbound Cruise spacecraft Sun-pointing attitude(i.e., Sun on +X), sunlight impinging on the PolyCam, OTES, IMU-sunshade and OLA-sunshade MLIs is reflected orscattered to the forward deck and components on the forward deck. It illuminates the forward deck. The StowCam imageof Day 265 2016 also provided an evidence. The reflected or scattered sunlight cause warming to the forward deck andcomponents on its +Z side. It may also contribute to degradation of thermal coatings over the mission life. It is a factorthat the OVIRS detector operating temperature exceeds the 105K maximum AFT limit. The OVIRS PrincipalInvestigator indicated that it is not optimum but acceptable for science. With exception of the OVIRS detector, thecorrelated flight system thermal model predictions for the components on the forward deck have adequate margins in theProximity Ops, TAG and Return Cruise phases. The margins are expected to cover the warming caused by the solarimpingement and the contribution to degradation of thermal coatings. The solar impingement is not expected to be athermal risk to the OSIRIS-REx mission. The second SRC Optical Properties characterization will be repeated in theReturn Cruise to provide a good characterization of any changes in optical properties that might have occurred duringthe TAG, or during several years in space. If the SRC battery runs much warmer than that of the first characterization inthe Outbound Cruise, it will be necessary to make some changes to the SRC Release timeline to assure the SRC batterytemperature are within limits. If GBK, instead of microporous black PTFE, were used on the PolyCam sunshade MLI,much more sunlight would have been reflected or scattered to the forward deck and components on its +Z side.Microporous black PTFE should be considered to mitigate the optical and thermal issues of sunlight reflected/scatteredby MLI blankets in future missions.

PHOBOS AS A D-TYPE CAPTURED ASTEROID, SPECTRAL MODELING FROM 0.25 TO 4.0 μm

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pajola, M.; Magrin, S.; Bertini, I.

This paper describes the spectral modeling of the surface of Phobos in the wavelength range between 0.25 and 4.0 μm. We use complementary data to cover this spectral range: the OSIRIS (Optical, Spectroscopic, and Infrared Remote Imaging System on board the ESA Rosetta spacecraft) reflectance spectrum that Pajola et al. merged with the VSK-KRFM-ISM (Videospectrometric Camera (VSK)-Combined Radiometer and Photometer for Mars (KRFM)-Imaging Spectrometer for Mars (ISM) on board the USSR Phobos 2 spacecraft) spectra by Murchie and Erard and the IRTF (NASA Infrared Telescope Facility, Hawaii, USA) spectra published by Rivkin et al. The OSIRIS data allow the characterizationmore » of an area of Phobos covering from 86.°8 N to 90° S in latitude and from 126° W to 286° W in longitude. This corresponds chiefly to the trailing hemisphere, but with a small sampling of the leading hemisphere as well. We compared the OSIRIS results with the Trojan D-type asteroid 624 Hektor and show that the overall slope and curvature of the two bodies over the common wavelength range are very similar. This favors Phobos being a captured D-type asteroid as previously suggested. We modeled the OSIRIS data using two models, the first one with a composition that includes organic carbonaceous material, serpentine, olivine, and basalt glass, and the second one consisting of Tagish Lake meteorite and magnesium-rich pyroxene glass. The results of these models were extended to longer wavelengths to compare the VSK-KRFM-ISM and IRTF data. The overall shape of the second model spectrum between 0.25 and 4.0 μm shows curvature and an albedo level that match both the OSIRIS and Murchie and Erard data and the Rivkin et al. data much better than the first model. The large interval fit is encouraging and adds weight to this model, making it our most promising fit for Phobos. Since Tagish Lake is commonly used as a spectral analog for D-type asteroids, this provides additional support for compositional similarities between Phobos and D-type asteroids.« less

[Neurosurgical planning using osirix software].

PubMed

Jaimovich, Sebastián Gastón; Guevara, Martin; Pampin, Sergio; Jaimovich, Roberto; Gardella, Javier Luis

2014-01-01

Anatomical individuality is key to reduce surgical trauma and obtain a better outcome. Nowadays, the advances in neuroimaging has allowed us to analyze this anatomical individuality and to plan the surgery. With this objective, we present our experience with the OsiriX software. We present three different applications as example of forty procedures performed. Case 1: Patient with a premotor cortex convexity parasagittal meningioma; Case 2: Patient with a nonfunctioning pituitary macroadenoma operated on 2 years ago in another institution, achieving a partial resection by a transsphenoidal approach; Case 3: Patient with bilateral middle cerebellar peduncles lesions. OsiriX Software was used for surgical planning. Volumetric CT and MRI images were fused and 3D reconstruction images obtained, to analyze anatomical relationships, measure distances, coordinates and trajectories, among other features. OsiriX software is a useful, open-source and free software tool that provides the surgeon with valuable information. It allows to study individual patient's anatomy and plan a surgical approach in a fast, simple, inexpensive and safety way. In Case 1 the software let us analyze the relationship of the tumor with the surrounding structures in order to minimize the approach's morbidity. In Case 2, to understand the unique anatomic characteristics of an already operated patient giving us important information regarding pathways and need for extra bone removal, achieving a complete tumor resection by an endoscopic transnasal approach. In Case 3, allowed us to obtain the stereotactic coordinates and trajectory for a not visualizable CT scan lesion. When expensive neuronavigation systems are not available, OsiriX is an alternative for neurosurgical planning, with the aim of reducing trauma and surgical morbidity.

You can't touch this: touch-free navigation through radiological images.

PubMed

Ebert, Lars C; Hatch, Gary; Ampanozi, Garyfalia; Thali, Michael J; Ross, Steffen

2012-09-01

Keyboards, mice, and touch screens are a potential source of infection or contamination in operating rooms, intensive care units, and autopsy suites. The authors present a low-cost prototype of a system, which allows for touch-free control of a medical image viewer. This touch-free navigation system consists of a computer system (IMac, OS X 10.6 Apple, USA) with a medical image viewer (OsiriX, OsiriX foundation, Switzerland) and a depth camera (Kinect, Microsoft, USA). They implemented software that translates the data delivered by the camera and a voice recognition software into keyboard and mouse commands, which are then passed to OsiriX. In this feasibility study, the authors introduced 10 medical professionals to the system and asked them to re-create 12 images from a CT data set. They evaluated response times and usability of the system compared with standard mouse/keyboard control. Users felt comfortable with the system after approximately 10 minutes. Response time was 120 ms. Users required 1.4 times more time to re-create an image with gesture control. Users with OsiriX experience were significantly faster using the mouse/keyboard and faster than users without prior experience. They rated the system 3.4 out of 5 for ease of use in comparison to the mouse/keyboard. The touch-free, gesture-controlled system performs favorably and removes a potential vector for infection, protecting both patients and staff. Because the camera can be quickly and easily integrated into existing systems, requires no calibration, and is low cost, the barriers to using this technology are low.

Leveraging social media in the stem cell sector: exploring Twitter's potential as a vehicle for public information campaigns.

PubMed

McNutt, Kathleen; Zarzeczny, Amy

2017-10-01

Our aim in this project was to explore Twitter's potential as a vehicle for an online public information campaign (PIC) focused on providing evidence-based information about stem cell therapies and the market for unproven stem cell-based interventions. We designed an online, Twitter-based PIC using classic design principles and identified a set of target intermediaries (organizations with online influence) using a network governance approach. We tracked the PIC's dissemination over a 2-month period, and evaluated it using metrics from the #SMMStandards Conclave. Participation was limited but the PIC achieved some reach and engagement. Social media based online PICs appear to have potential but also face challenges. Future research is required to better understand how to most effectively maximize their strengths.

J0815+4729: A Chemically Primitive Dwarf Star in the Galactic Halo Observed with Gran Telescopio Canarias

NASA Astrophysics Data System (ADS)

Aguado, David S.; González Hernández, Jonay I.; Allende Prieto, Carlos; Rebolo, Rafael

2018-01-01

We report the discovery of the carbon-rich hyper metal-poor unevolved star J0815+4729. This dwarf star was selected from SDSS/BOSS as a metal-poor candidate and follow-up spectroscopic observations at medium resolution were obtained with the Intermediate dispersion Spectrograph and Imaging System (ISIS) at William Herschel Telescope and the Optical System for Imaging and low-intermediate-Resolution Integrated Spectroscopy (OSIRIS) at Gran Telescopio de Canarias. We use the FERRE code to derive the main stellar parameters, {T}{eff}=6215+/- 82 K, and {log}g=4.7+/- 0.5, an upper limit to the metallicity of [Fe/H] ≤ ‑5.8, and a carbon abundance of [C/Fe] ≥ +5.0, while [α /{Fe}]=0.4 is assumed. The metallicity upper limit is based on the Ca II K line, which at the resolving power of the OSIRIS spectrograph cannot be resolved from possible interstellar calcium. The star could be the most iron-poor unevolved star known and also be among the ones with the largest overabundances of carbon. High-resolution spectroscopy of J0815+4729 will certainly help to derive other important elemental abundances, possibly providing new fundamental constraints on the early stages of the universe, the formation of the first stars, and the properties of the first supernovae. Based on observations made with the Gran Telescopio Canarias (GTC), installed in the Spanish Observatorio del Roque de los Muchachos of the Instituto de Astrofísica de Canarias, on the island of La Palma. Program ID GTC90-15B and the Discretionary Director Time GTC03-16ADDT and also based on observations made with the William Herschel Telescope (WHT).

New ultra metal-poor stars from SDSS: follow-up GTC medium-resolution spectroscopy

NASA Astrophysics Data System (ADS)

Aguado, D. S.; Allende Prieto, C.; González Hernández, J. I.; Rebolo, R.; Caffau, E.

2017-07-01

Context. The first generation of stars formed in the Galaxy left behind the chemical signatures of their nucleosynthesis in the interstellar medium, visible today in the atmospheres of low-mass stars that formed afterwards. Sampling the chemistry of those low-mass provides insight into the first stars. Aims: We aim to increase the samples of stars with extremely low metal abundances, identifying ultra metal-poor stars from spectra with modest spectral resolution and signal-to-noise ratio (S/N). Achieving this goal involves deriving reliable metallicities and carbon abundances from such spectra. Methods: We carry out follow-up observations of faint, V > 19, metal-poor candidates selected from SDSS spectroscopy and observed with the Optical System for Imaging and low-Intermediate-Resolution Integrated Spectroscopy (OSIRIS) at GTC. The SDSS and follow-up OSIRIS spectra were analyzed using the FERRE code to derive effective temperatures, surface gravities, metallicities and carbon abundances. In addition, a well-known extremely metal-poor star has been included in our sample to calibrate the analysis methodology. Results: We observed and analyzed five metal-poor candidates from modest-quality SDSS spectra. All stars in our sample have been confirmed as extremely metal-poor stars, in the [Fe/H] < -3.3 regime. We report the recognition of J173403+644632, a carbon-enhanced ultra metal-poor dwarf star with [Fe/H] = -4.3 and [C/Fe] = + 3.1. Based on observations made with the Gran Telescopio Canarias (GTC), installed in the Spanish Observatorio del Roque de los Muchachos of the Instituto de Astrofísica de Canarias, on the island of La Palma. Programme ID GTC2E-16A and ID GTC65-16B.

Development of a robust pH-sensitive polyelectrolyte ionomer complex for anticancer nanocarriers

PubMed Central

Lim, Chaemin; Youn, Yu Seok; Lee, Kyung Soo; Hoang, Ngoc Ha; Sim, Taehoon; Lee, Eun Seong; Oh, Kyung Taek

2016-01-01

A polyelectrolyte ionomer complex (PIC) composed of cationic and anionic polymers was developed for nanomedical applications. Here, a poly(ethylene glycol)–poly(lactic acid)–poly(ethylene imine) triblock copolymer (PEG–PLA–PEI) and a poly(aspartic acid) (P[Asp]) homopolymer were synthesized. These polyelectrolytes formed stable aggregates through electrostatic interactions between the cationic PEI and the anionic P(Asp) blocks. In particular, the addition of a hydrophobic PLA and a hydrophilic PEG to triblock copolyelectrolytes provided colloidal aggregation stability by forming a tight hydrophobic core and steric hindrance on the surface of PIC, respectively. The PIC showed different particle sizes and zeta potentials depending on the ratio of cationic PEI and anionic P(Asp) blocks (C/A ratio). The doxorubicin (dox)-loaded PIC, prepared with a C/A ratio of 8, demonstrated pH-dependent behavior by the deprotonation/protonation of polyelectrolyte blocks. The drug release and the cytotoxicity of the dox-loaded PIC (C/A ratio: 8) increased under acidic conditions compared with physiological pH, due to the destabilization of the formation of the electrostatic core. In vivo animal imaging revealed that the prepared PIC accumulated at the targeted tumor site for 24 hours. Therefore, the prepared pH-sensitive PIC could have considerable potential as a nanomedicinal platform for anticancer therapy. PMID:26955270

Modelling of the inner gas and dust coma of comet 67P/Churyumov-Gerasimenko using ROSINA/COPS and OSIRIS data - First results

NASA Astrophysics Data System (ADS)

Marschall, R.; Su, C. C.; Liao, Y.; Thomas, N.; Wu, J. S.; Altwegg, K.; Sierks, H.; Ip, W.-H.; Keller, H. U.; Knollenberg, J.; Kührt, E.; Lai, I. L.; Rubin, M.; Skorov, Y.; Jorda, L.; Preusker, F.; Scholten, F.; Gicquel, A.; Gracia-Berná, A.; Naletto, G.

2015-10-01

The physics of the outflow above the surface of comets is somewhat complex. Ice sublimating into vacuum forms a non-equilibrium boundary layer, the "Knudsen layer" (Kn-layer), with a scale height of #20 mean free paths. If the production rate is low, the Kn-layer becomes infinitely thick and the velocity distribution function (VDF) remains strongly non-Maxwellian. Thus our preferred method for gas dynamics simulations of the coma is Direct Simulation Monte Carlo DSMC. Here we report on the first results of models of the outflow from the Rosetta target, comet67P/Churyumov-Gerasimenko (C-G). Our aims are to (1) determine the gas flow-field of H2O and CO2 in the innermost coma and compare the results to the in-situ measurements of the ROSINA/COPS instrument (2) produce artificial images of the dust brightnesses that can be compared to the OSIRIS cameras. The comparison with ROSINA/COPS and OSIRIS data help to constrain the initial conditions of the simulations and thus yield information on the surface processes.

BENNU’S JOURNEY

NASA Image and Video Library

2017-12-08

This large asteroid, a proto-star undergoes fusion and our sun is born. This is the parent of Asteroid Bennu. Today, a NASA Spacecraft has the chance to retrieve a sample from Bennu to reveal the history of our solar system. OSIRIRS-REx is a NASA sample return mission to visit Asteroid Bennu. We plan to grab a piece of Bennu, because it’s a time capsule that can tell us about the origins of our planet and our entire solar system. Watch the full video: youtu.be/gtUgarROs08 Learn more about NASA’s OSIRIS-REx mission and the making of Bennu’s Journey: www.nasa.gov/content/goddard/bennus-journey/ More information on the OSIRIS-REx mission is available at: www.nasa.gov/mission_pages/osiris-rex/index.html www.asteroidmission.org NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

Distance determination method of dust particles using Rosetta OSIRIS NAC and WAC data

NASA Astrophysics Data System (ADS)

Drolshagen, E.; Ott, T.; Koschny, D.; Güttler, C.; Tubiana, C.; Agarwal, J.; Sierks, H.; Barbieri, C.; Lamy, P. I.; Rodrigo, R.; Rickman, H.; A'Hearn, M. F.; Barucci, M. A.; Bertaux, J.-L.; Bertini, I.; Cremonese, G.; da Deppo, V.; Davidsson, B.; Debei, S.; de Cecco, M.; Deller, J.; Feller, C.; Fornasier, S.; Fulle, M.; Gicquel, A.; Groussin, O.; Gutiérrez, P. J.; Hofmann, M.; Hviid, S. F.; Ip, W.-H.; Jorda, L.; Keller, H. U.; Knollenberg, J.; Kramm, J. R.; Kührt, E.; Küppers, M.; Lara, L. M.; Lazzarin, M.; Lopez Moreno, J. J.; Marzari, F.; Naletto, G.; Oklay, N.; Shi, X.; Thomas, N.; Poppe, B.

2017-09-01

The ESA Rosetta spacecraft has been tracking its target, the Jupiter-family comet 67P/Churyumov-Gerasimenko, in close vicinity for over two years. It hosts the OSIRIS instruments: the Optical, Spectroscopic, and Infrared Remote Imaging System composed of two cameras, see e.g. Keller et al. (2007). In some imaging sequences dedicated to observe dust particles in the comet's coma, the two cameras took images at the same time. The aim of this work is to use these simultaneous double camera observations to calculate the dust particles' distance to the spacecraft. As the two cameras are mounted on the spacecraft with an offset of 70 cm, the distance of particles observed by both cameras can be determined by a shift of the particles' apparent trails on the images. This paper presents first results of the ongoing work, introducing the distance determination method for the OSIRIS instrument and the analysis of an example particle. We note that this method works for particles in the range of about 500-6000 m from the spacecraft.

Hot DA white dwarf model atmosphere calculations: including improved Ni PI cross-sections

NASA Astrophysics Data System (ADS)

Preval, S. P.; Barstow, M. A.; Badnell, N. R.; Hubeny, I.; Holberg, J. B.

2017-02-01

To calculate realistic models of objects with Ni in their atmospheres, accurate atomic data for the relevant ionization stages need to be included in model atmosphere calculations. In the context of white dwarf stars, we investigate the effect of changing the Ni IV-VI bound-bound and bound-free atomic data on model atmosphere calculations. Models including photoionization cross-section (PICS) calculated with AUTOSTRUCTURE show significant flux attenuation of up to ˜80 per cent shortward of 180 Å in the extreme ultraviolet (EUV) region compared to a model using hydrogenic PICS. Comparatively, models including a larger set of Ni transitions left the EUV, UV, and optical continua unaffected. We use models calculated with permutations of these atomic data to test for potential changes to measured metal abundances of the hot DA white dwarf G191-B2B. Models including AUTOSTRUCTURE PICS were found to change the abundances of N and O by as much as ˜22 per cent compared to models using hydrogenic PICS, but heavier species were relatively unaffected. Models including AUTOSTRUCTURE PICS caused the abundances of N/O IV and V to diverge. This is because the increased opacity in the AUTOSTRUCTURE PICS model causes these charge states to form higher in the atmosphere, more so for N/O V. Models using an extended line list caused significant changes to the Ni IV-V abundances. While both PICS and an extended line list cause changes in both synthetic spectra and measured abundances, the biggest changes are caused by using AUTOSTRUCTURE PICS for Ni.

Estimating Particulate Inorganic Carbon Concentrations of the Global Ocean From Ocean Color Measurements Using a Reflectance Difference Approach

NASA Astrophysics Data System (ADS)

Mitchell, C.; Hu, C.; Bowler, B.; Drapeau, D.; Balch, W. M.

2017-11-01

A new algorithm for estimating particulate inorganic carbon (PIC) concentrations from ocean color measurements is presented. PIC plays an important role in the global carbon cycle through the oceanic carbonate pump, therefore accurate estimations of PIC concentrations from satellite remote sensing are crucial for observing changes on a global scale. An extensive global data set was created from field and satellite observations for investigating the relationship between PIC concentrations and differences in the remote sensing reflectance (Rrs) at green, red, and near-infrared (NIR) wavebands. Three color indices were defined: two as the relative height of Rrs(667) above a baseline running between Rrs(547) and an Rrs in the NIR (either 748 or 869 nm), and one as the difference between Rrs(547) and Rrs(667). All three color indices were found to explain over 90% of the variance in field-measured PIC. But, due to the lack of availability of Rrs(NIR) in the standard ocean color data products, most of the further analysis presented here was done using the color index determined from only two bands. The new two-band color index algorithm was found to retrieve PIC concentrations more accurately than the current standard algorithm used in generating global PIC data products. Application of the new algorithm to satellite imagery showed patterns on the global scale as revealed from field measurements. The new algorithm was more resistant to atmospheric correction errors and residual errors in sun glint corrections, as seen by a reduction in the speckling and patchiness in the satellite-derived PIC images.

Effects of Chromium Picolinate on Food Intake and Satiety

PubMed Central

Morrison, Christopher D.; Cefalu, William T.; Martin, Corby K.; Coulon, Sandra; Geiselman, Paula; Han, Hongmei; White, Christy L.; Williamson, Donald A.

2008-01-01

Abstract Background Chromium picolinate (CrPic) has been shown to attenuate weight gain, but the mechanism underlying this effect is unknown. Methods We assessed the effect of CrPic in modulating food intake in healthy, overweight, adult women who reported craving carbohydrates (Study 1) and performed confirmatory studies in Sprague-Dawley rats (Study 2). Study 1 utilized a double-blind placebo-controlled design and randomly assigned 42 overweight adult women with carbohydrate cravings to receive 1,000 μg of chromium as CrPic or placebo for 8 weeks. Food intake at breakfast, lunch, and dinner was directly measured at baseline, week 1, and week 8. For Study 2, Sprague-Dawley rats were fasted for 24 h and subsequently injected intraperitoneally with 0, 1, 10, or 50 μg/kg CrPic. Subsequently, rats were implanted with an indwelling third ventricular cannula. Following recovery, 0, 0.4, 4, or 40 ng of CrPic was injected directly into the brain via the intracerebroventricular cannula, and spontaneous 24-h food intake was measured. Results Study 1 demonstrated that CrPic, as compared to placebo, reduced food intake (P < 0.0001), hunger levels (P < 0.05), and fat cravings (P < 0.0001) and tended to decrease body weight (P = 0.08). In study 2, intraperitoneal administration resulted in a subtle decrease in food intake at only the highest dose (P = 0.03). However, when administered centrally, CrPic dose-dependently decreased food intake (P < 0.05). Conclusions These data suggest CrPic has a role in food intake regulation, which may be mediated by a direct effect on the brain. PMID:18715218

46 CFR 13.309 - Eligibility: Cargo course.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 1 2013-10-01 2013-10-01 false Eligibility: Cargo course. 13.309 Section 13.309... TANKERMEN Requirements for âTankerman-PIC (Barge)â Endorsement § 13.309 Eligibility: Cargo course. Each... a course in DL or LG appropriate for tank barges and for Tankerman-PIC or Tankerman-PIC (Barge), and...

46 CFR 13.309 - Eligibility: Cargo course.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 1 2012-10-01 2012-10-01 false Eligibility: Cargo course. 13.309 Section 13.309... TANKERMEN Requirements for âTankerman-PIC (Barge)â Endorsement § 13.309 Eligibility: Cargo course. Each... a course in DL or LG appropriate for tank barges and for Tankerman-PIC or Tankerman-PIC (Barge), and...

46 CFR 13.309 - Eligibility: Cargo course.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 1 2010-10-01 2010-10-01 false Eligibility: Cargo course. 13.309 Section 13.309... TANKERMEN Requirements for âTankerman-PIC (Barge)â Endorsement § 13.309 Eligibility: Cargo course. Each... a course in DL or LG appropriate for tank barges and for Tankerman-PIC or Tankerman-PIC (Barge), and...

46 CFR 13.309 - Eligibility: Cargo course.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 1 2011-10-01 2011-10-01 false Eligibility: Cargo course. 13.309 Section 13.309... TANKERMEN Requirements for âTankerman-PIC (Barge)â Endorsement § 13.309 Eligibility: Cargo course. Each... a course in DL or LG appropriate for tank barges and for Tankerman-PIC or Tankerman-PIC (Barge), and...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shoup, R.W.; Long, F.; Martin, T.H.

Sandia is developing PBFA-Z, a 20-MA driver for z-pinch experiments by replacing the water lines, insulator stack, and MITLs on PBFA II with new hardware. The design of the vacuum insulator stack was dictated by the drive voltage, the electric field stress and grading requirements, the water line and MITL interface requirements, and the machine operations and maintenance requirements. The insulator stack will consist of four separate modules, each of a different design because of different voltage drive and hardware interface requirements. The shape of the components in each module, i.e., grading rings, insulator rings, flux excluders, anode and cathodemore » conductors, and the design of the water line and MITL interfaces, were optimized by using the electrostatic analysis codes, ELECTRO and JASON. The time dependent performance of the insulator stack was evaluated using IVORY, a 2-D PIC code. This paper will describe the insulator stack design and present the results of the ELECTRO and IVORY analyses.« less

Self-consistent simulation of radio frequency multipactor on micro-grooved dielectric surface

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cai, Libing; Wang, Jianguo, E-mail: wanguiuc@mail.xjtu.edu.cn; Northwest Institute of Nuclear Technology, Xi'an, Shaanxi 710024

2015-02-07

The multipactor plays a key role in the surface breakdown on the feed dielectric window irradiated by high power microwave. To study the suppression of multipactor, a 2D electrostatic PIC-MCC simulation code was developed. The space charge field, including surface deposited charge and multipactor electron charge field, is obtained by solving 2D Poisson's equation in time. Therefore, the simulation is self-consistent and does not require presetting a fixed space charge field. By using this code, the self-consistent simulation of the RF multipactor on the periodic micro-grooved dielectric surface is realized. The 2D space distributions of the multipactor electrons and spacemore » charge field are presented. From the simulation results, it can be found that only half slopes have multipactor discharge when the slope angle exceeds a certain value, and the groove presents a pronounced suppression effect on the multipactor.« less

Studies of particle wake potentials in plasmas

NASA Astrophysics Data System (ADS)

Ellis, Ian N.; Graziani, Frank R.; Glosli, James N.; Strozzi, David J.; Surh, Michael P.; Richards, David F.; Decyk, Viktor K.; Mori, Warren B.

2011-09-01

A detailed understanding of electron stopping and scattering in plasmas with variable values for the number of particles within a Debye sphere is still not at hand. Presently, there is some disagreement in the literature concerning the proper description of these processes. Theoretical models assume electrostatic (Coulomb force) interactions between particles and neglect magnetic effects. Developing and validating proper descriptions requires studying the processes using first-principle plasma simulations. We are using the particle-particle particle-mesh (PPPM) code ddcMD and the particle-in-cell (PIC) code BEPS to perform these simulations. As a starting point in our study, we examine the wake of a particle passing through a plasma in 3D electrostatic simulations performed with ddcMD and BEPS. In this paper, we compare the wakes observed in these simulations with each other and predictions from collisionless kinetic theory. The relevance of the work to Fast Ignition is discussed.

Modeling multi-GeV class laser-plasma accelerators with INF&RNO

NASA Astrophysics Data System (ADS)

Benedetti, Carlo; Schroeder, Carl; Bulanov, Stepan; Geddes, Cameron; Esarey, Eric; Leemans, Wim

2016-10-01

Laser plasma accelerators (LPAs) can produce accelerating gradients on the order of tens to hundreds of GV/m, making them attractive as compact particle accelerators for radiation production or as drivers for future high-energy colliders. Understanding and optimizing the performance of LPAs requires detailed numerical modeling of the nonlinear laser-plasma interaction. We present simulation results, obtained with the computationally efficient, PIC/fluid code INF&RNO (INtegrated Fluid & paRticle simulatioN cOde), concerning present (multi-GeV stages) and future (10 GeV stages) LPA experiments performed with the BELLA PW laser system at LBNL. In particular, we will illustrate the issues related to the guiding of a high-intensity, short-pulse, laser when a realistic description for both the laser driver and the background plasma is adopted. Work Supported by the U.S. Department of Energy under contract No. DE-AC02-05CH11231.

Two-dimensional simulation research of secondary electron emission avalanche discharge on vacuum insulator surface

NASA Astrophysics Data System (ADS)

Cai, Libing; Wang, Jianguo; Zhu, Xiangqin; Wang, Yue; Zhang, Dianhui

2015-01-01

Based on the secondary electron emission avalanche (SEEA) model, the SEEA discharge on the vacuum insulator surface is simulated by using a 2D PIC-MCC code developed by ourselves. The evolutions of the number of discharge electrons, insulator surface charge, current, and 2D particle distribution are obtained. The effects of the strength of the applied electric field, secondary electron yield coefficient, rise time of the pulse, length of the insulator on the discharge are investigated. The results show that the number of the SEEA electrons presents a quadratic dependence upon the applied field strength. The SEEA current, which is on the order of Ampere, is directly proportional to the field strength and secondary electron yield coefficient. Finally, the electron-stimulated outgassing is included in the simulation code, and a three-phase discharge curve is presented by the simulation, which agrees with the experimental data.

A treecode to simulate dust-plasma interactions

NASA Astrophysics Data System (ADS)

Thomas, D. M.; Holgate, J. T.

2017-02-01

The interaction of a small object with surrounding plasma is an area of plasma-physics research with a multitude of applications. This paper introduces the plasma octree code pot, a microscopic simulator of a spheroidal dust grain in a plasma. pot uses the Barnes-Hut treecode algorithm to perform N-body simulations of electrons and ions in the vicinity of a chargeable spheroid, employing also the Boris particle-motion integrator and Hutchinson’s reinjection algorithm from SCEPTIC; a description of the implementation of all three algorithms is provided. We present results from pot simulations of the charging of spheres in magnetised plasmas, and of spheroids in unmagnetized plasmas. The results call into question the validity of using the Boltzmann relation in hybrid PIC codes. Substantial portions of this paper are adapted from chapters 4 and 5 of the first author’s recent PhD dissertation.

ICPP: Relativistic Plasma Physics with Ultra-Short High-Intensity Laser Pulses

NASA Astrophysics Data System (ADS)

Meyer-Ter-Vehn, Juergen

2000-10-01

Recent progress in generating ultra-short high-intensity laser pulses has opened a new branch of relativistic plasma physics, which is discussed in this talk in terms of particle-in-cell (PIC) simulations. These pulses create small plasma volumes of high-density plasma with plasma fields above 10^12 V/m and 10^8 Gauss. At intensities beyond 10^18 W/cm^2, now available from table-top systems, they drive relativistic electron currents in self-focussing plasma channels. These currents are close to the Alfven limit and allow to study relativistic current filamentation. A most remarkable feature is the generation of well collimated relativistic electron beams emerging from the channels with energies up to GeV. In dense matter they trigger cascades of gamma-rays, e^+e^- pairs, and a host of nuclear and particle processes. One of the applications may be fast ignition of compressed inertial fusion targets. Above 10^23 W/cm^2, expected to be achieved in the future, solid-density matter becomes relativistically transparent for optical light, and the acceleration of protons to multi-GeV energies is predicted in plasma layers less than 1 mm thick. These results open completely new perspectives for plasma-based accelerator schemes. Three-dimensional PIC simulations turn out to be the superior tool to explore the relativistic plasma kinetics at such intensities. Results obtained with the VLPL code [1] are presented. Different mechanisms of particle acceleration are discussed. Both laser wakefield and direct laser acceleration in plasma channels (by a mechanism similar to inverse free electron lasers) have been identified. The latter describes recent MPQ experimental results. [1] A. Pukhov, J. Plasma Physics 61, 425 - 433 (1999): Three-dimensional electromagnetic relativistic particle-in-cell code VLPL (Virtual Laser Plasma Laboratory).

Steady-State Ion Beam Modeling with MICHELLE

NASA Astrophysics Data System (ADS)

Petillo, John

2003-10-01

There is a need to efficiently model ion beam physics for ion implantation, chemical vapor deposition, and ion thrusters. Common to all is the need for three-dimensional (3D) simulation of volumetric ion sources, ion acceleration, and optics, with the ability to model charge exchange of the ion beam with a background neutral gas. The two pieces of physics stand out as significant are the modeling of the volumetric source and charge exchange. In the MICHELLE code, the method for modeling the plasma sheath in ion sources assumes that the electron distribution function is a Maxwellian function of electrostatic potential over electron temperature. Charge exchange is the process by which a neutral background gas with a "fast" charged particle streaming through exchanges its electron with the charged particle. An efficient method for capturing this is essential, and the model presented is based on semi-empirical collision cross section functions. This appears to be the first steady-state 3D algorithm of its type to contain multiple generations of charge exchange, work with multiple species and multiple charge state beam/source particles simultaneously, take into account the self-consistent space charge effects, and track the subsequent fast neutral particles. The solution used by MICHELLE is to combine finite element analysis with particle-in-cell (PIC) methods. The basic physics model is based on the equilibrium steady-state application of the electrostatic particle-in-cell (PIC) approximation employing a conformal computational mesh. The foundation stems from the same basic model introduced in codes such as EGUN. Here, Poisson's equation is used to self-consistently include the effects of space charge on the fields, and the relativistic Lorentz equation is used to integrate the particle trajectories through those fields. The presentation will consider the complexity of modeling ion thrusters.

Improved Membership Probability for Moving Groups: Bayesian and Machine Learning Approaches

NASA Astrophysics Data System (ADS)

Lee, Jinhee; Song, Inseok

2018-01-01

Gravitationally unbound loose stellar associations (i.e., young nearby moving groups: moving groups hereafter) have been intensively explored because they are important in planet and disk formation studies, exoplanet imaging, and age calibration. Among the many efforts devoted to the search for moving group members, a Bayesian approach (e.g.,using the code BANYAN) has become popular recently because of the many advantages it offers. However, the resultant membership probability needs to be carefully adopted because of its sensitive dependence on input models. In this study, we have developed an improved membership calculation tool focusing on the beta-Pic moving group. We made three improvements for building models used in BANYAN II: (1) updating a list of accepted members by re-assessing memberships in terms of position, motion, and age, (2) investigating member distribution functions in XYZ, and (3) exploring field star distribution functions in XYZUVW. Our improved tool can change membership probability up to 70%. Membership probability is critical and must be better defined. For example, our code identifies only one third of the candidate members in SIMBAD that are believed to be kinematically associated with beta-Pic moving group.Additionally, we performed cluster analysis of young nearby stars using an unsupervised machine learning approach. As more moving groups and their members are identified, the complexity and ambiguity in moving group configuration has been increased. To clarify this issue, we analyzed ~4,000 X-ray bright young stellar candidates. Here, we present the preliminary results. By re-identifying moving groups with the least human intervention, we expect to understand the composition of the solar neighborhood. Moreover better defined moving group membership will help us understand star formation and evolution in relatively low density environments; especially for the low-mass stars which will be identified in the coming Gaia release.

Chemical properties and biotoxicity of several chromium picolinate derivatives.

PubMed

Liu, Bin; Liu, Yanfei; Chai, Jie; Hu, Xiangquan; Wu, Duoming; Yang, Binsheng

2016-11-01

As a man-made additive, chromium picolinate Cr(pic) 3 has become a popular dietary supplement worldwide. In this paper Cr(pic) 3 and its new derivatives Cr(6-CH 3 -pic) 3 (1), [Cr(6-NH 2 -pic) 2 (H 2 O) 2 ]NO 3 (2) and Cr(3-NH 2 -pic) 3 (3) were synthesized, and complexes 1 and 2 were characterized by X-ray crystal structure (where pic=2-carboxypyridine). The relationship between the chemical properties and biotoxicity of these complexes was fully discussed: (1) The dynamics stability of chromium picolinate complexes mainly depends on the CrN bonds length. (2) There is a positive correlation between the dynamics stability, electrochemical potentials and generation of reactive oxygen species through Fenton-like reaction. (3) However, no biological toxicity was observed through MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) and sub-chronic oral toxicity study for these chromium picolinate compounds. Together, our findings establish a framework for understanding the structure-property-toxicity relationships of the chromium picolinate complexes. Copyright © 2016 Elsevier Inc. All rights reserved.

Effects of chromium picolinate on the viability of chick embryo fibroblast.

PubMed

Bai, Y; Zhao, X; Qi, C; Wang, L; Cheng, Z; Liu, M; Liu, J; Yang, D; Wang, S; Chai, T

2014-04-01

Chromium picolinate (CrPic), which is used as a nutritional supplement and to treat type 2 diabetes, has gained much attention because of its cytotoxicity. This study evaluated the effects of CrPic on the viability of the chick embryo fibroblast (CEF) using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay, morphological detection, and flow cytometry. The results show that lower concentrations of CrPic (8 and 16 μM) did not damage CEF viability (p > 0.05). However, higher CrPic concentrations (400 and 600 μM) indicated a highly significant effect on the production of intracellular reactive oxygen species, alteration of mitochondrial membrane potential, intracellular calcium ion concentration, and the apoptosis rate (p < 0.01), contrary to lower CrPic concentrations (8 and 16 μM) and control group. Moreover, apoptotic morphological changes induced by these processes in CEF were confirmed using Hoechst 33258 staining. Cell death induced by higher concentrations of CrPic was caused by an apoptotic and a necrotic mechanism, whereas the main mechanism of oxidative stress-induced mitochondrial dysfunction was apoptotic death.

Orbit Stability of OSIRIS-REx in the Vicinity of Bennu Using a High-Fidelity Solar Radiation Model

NASA Technical Reports Server (NTRS)

Williams, Trevor; Hughes, Kyle; Mashiku, Alinda; Longuski, James

2015-01-01

The OSIRIS-REx mission (Origins Spectral Interpretation Resource Identification Security Regolith EXPlorer) is an asteroid sample return mission to Bennu (RQ36) that is scheduled to launch in 2016. The planned science operations precluding the small retrieval involve operations in terminator orbits (orbit plane is perpendicular to the sun). Over longer durations the solar radiation pressure (SRP) perturbs the orbit causing it to precess. Our work involves: modeling high fidelity SRP model to capture the perturbations during attitude changes; design a stable orbit from the high fidelity models to analyze the stability over time.

OSIRIS-REx Rollout for Launch

NASA Image and Video Library

2016-09-07

A United Launch Alliance Atlas V rocket begins to roll out of the Vertical Integration Facility to Space Launch Complex 41 at Cape Canaveral Air Force Station in Florida. The launch vehicle will boost NASA’s Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer, or OSIRIS-REx spacecraft. This will be the first U.S. mission to sample an asteroid, retrieve at least two ounces of surface material and return it to Earth for study. The asteroid, Bennu, may hold clues to the origin of the solar system and the source of water and organic molecules found on Earth.

OSIRIS-REx Rollout for Launch

NASA Image and Video Library

2016-09-07

After leaving the Vertical Integration Facility, a United Launch Alliance Atlas V rocket is on its way to Space Launch Complex 41 at Cape Canaveral Air Force Station in Florida. The launch vehicle will boost NASA’s Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer, or OSIRIS-REx spacecraft. This will be the first U.S. mission to sample an asteroid, retrieve at least two ounces of surface material and return it to Earth for study. The asteroid, Bennu, may hold clues to the origin of the solar system and the source of water and organic molecules found on Earth.

OSIRIS-REx Rollout for Launch

NASA Image and Video Library

2016-09-07

In a view from above, a United Launch Alliance Atlas V rocket begins to roll out of the Vertical Integration Facility to Space Launch Complex 41 at Cape Canaveral Air Force Station in Florida. The launch vehicle will boost NASA’s Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer, or OSIRIS-REx spacecraft. This will be the first U.S. mission to sample an asteroid, retrieve at least two ounces of surface material and return it to Earth for study. The asteroid, Bennu, may hold clues to the origin of the solar system and the source of water and organic molecules found on Earth.

OSIRIS-REx Rollout for Launch

NASA Image and Video Library

2016-09-07

A United Launch Alliance Atlas V rocket rolls out of the Vertical Integration Facility on its way to Space Launch Complex 41 at Cape Canaveral Air Force Station in Florida. The launch vehicle will boost NASA’s Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer, or OSIRIS-REx spacecraft. This will be the first U.S. mission to sample an asteroid, retrieve at least two ounces of surface material and return it to Earth for study. The asteroid, Bennu, may hold clues to the origin of the solar system and the source of water and organic molecules found on Earth.

OSIRIS-REx Rollout for Launch

NASA Image and Video Library

2016-09-07

A United Launch Alliance Atlas V rocket has left the Vertical Integration Facility and is on its way to Space Launch Complex 41 at Cape Canaveral Air Force Station in Florida. The launch vehicle will boost NASA’s Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer, or OSIRIS-REx spacecraft. This will be the first U.S. mission to sample an asteroid, retrieve at least two ounces of surface material and return it to Earth for study. The asteroid, Bennu, may hold clues to the origin of the solar system and the source of water and organic molecules found on Earth.

OSIRIS-REx Rollout for Launch

NASA Image and Video Library

2016-09-07

The United Launch Alliance Atlas V rocket has made the trek from the Vertical Integration Facility to Space Launch Complex 41 at Cape Canaveral Air Force Station in Florida. The launch vehicle will boost NASA’s Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer, or OSIRIS-REx spacecraft. This will be the first U.S. mission to sample an asteroid, retrieve at least two ounces of surface material and return it to Earth for study. The asteroid, Bennu, may hold clues to the origin of the solar system and the source of water and organic molecules found on Earth.

OSIRIS-REx Rollout for Launch

NASA Image and Video Library

2016-09-07

A United Launch Alliance Atlas V rocket rolled out of the Vertical Integration Facility and is on its way to Space Launch Complex 41 at Cape Canaveral Air Force Station in Florida. The launch vehicle will boost NASA’s Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer, or OSIRIS-REx spacecraft. This will be the first U.S. mission to sample an asteroid, retrieve at least two ounces of surface material and return it to Earth for study. The asteroid, Bennu, may hold clues to the origin of the solar system and the source of water and organic molecules found on Earth.

A Collision Avoidance Strategy for a Potential Natural Satellite around the Asteroid Bennu for the OSIRIS-REx Mission

NASA Technical Reports Server (NTRS)

Mashiku, Alinda K.; Carpenter, J. Russell

2016-01-01

The cadence of proximity operations for the OSIRIS-REx mission may have an extra induced challenge given the potential of the detection of a natural satellite orbiting the asteroid Bennu. Current ground radar observations for object detection orbiting Bennu show no found objects within bounds of specific size and rotation rates. If a natural satellite is detected during approach, a different proximity operation cadence will need to be implemented as well as a collision avoidance strategy for mission success. A collision avoidance strategy will be analyzed using the Wald Sequential Probability Ratio Test.

Origins, Spectral Interpretation, Resource Identification, Security, Regolith Explorer Planning (OSIRIS-REx)

NASA Technical Reports Server (NTRS)

Nakamura-Messenger, Keiko; Messenger, Scott; Keller, Lindsay; Righter, Kevin

2014-01-01

Scientists at ARES are preparing to curate and analyze samples from the first U.S. mission to return samples from an asteroid. The Origins-Spectral Interpretation- Resource Identification-Security-Regolith Explorer, or OSIRIS-REx, was selected by NASA as the third mission in its New Frontiers Program. The robotic spacecraft will launch in 2016 and rendezvous with the near-Earth asteroid Bennu, in 2020. A robotic arm will collect at least 60 grams of material from the surface of the asteroid to be returned to Earth in 2023 for worldwide distribution by the NASA Astromaterials Curation Facility at ARES.

A Collision Avoidance Strategy for a Potential Natural Satellite Around the Asteroid Bennu for the OSIRIS-REx Mission

NASA Technical Reports Server (NTRS)

Mashiku, Alinda; Carpenter, Russell

2016-01-01

The cadence of proximity operations for the OSIRIS-REx mission may have an extra induced challenge given the potential of the detection of a natural satellite orbiting the asteroid Bennu. Current ground radar observations for object detection orbiting Bennu show no found objects within bounds of specific size and rotation rates. If a natural satellite is detected during approach, a different proximity operation cadence will need to be implemented as well as a collision avoidance strategy for mission success. A collision avoidance strategy will be analyzed using the Wald Sequential Probability Ratio Test.

Material strength on 67P/Churyumov-Gerasimenko and its influence on cliff stability

NASA Astrophysics Data System (ADS)

Hofmann, Marc; Güttler, Carsten; Vincent, Jean-Baptiste; Prasanna Deshapriya, J. D.; Pajola, Maurizio; Tubiana, Cecilia; Feller, Clément; Barucci, Maria A.; Sierks, Holger

2017-04-01

The OSIRIS scientific camera system [1] on board ESA's Rosetta spacecraft has been observing comet 67P/Churyumov-Gerasimenko since its arrival in August 2014. Visible on the OSIRIS images are cliff structures with associated taluses at their bottom. It is likely that these taluses were created during a (partial) collapse of the neighboring cliff. Several of these taluses display individual boulders with different brightness and spectral slope than the rest of the boulders, indicating a varying content of volatiles. A possible cause for the collapse of cliffs is thermal stresses and heat that intensify the fracturing of possibly pre-fractured walls or form new fractures. This results in sublimation with a progressively eroding cliff. The direct consequence is the occurrence of gravitational events and formation of boulder fields at the foot of the cliffs [2,3]. Both of these processes serve to weaken the structural integrity of the cliff but it is unclear how large the relative contribution of these processes is. In this study we investigate how the depletion of volatiles and damage to the cliff structure introduced by cracks will change the integrity and stability of the cliff. We aim to derive limits to the material strength to be compared to those found from observed cliffs and cliff collapses [4,5] using the DEM software ESyS Particle [6]. Acknowledgements: OSIRIS was built by a consortium led by the Max-Planck-Institut für Sonnensystemforschung, Göttingen, Germany, in collaboration with CISAS, University of Padova, Italy, the Laboratoire d'Astrophysique de Marseille, France, the Instituto de Astrofísica de Andalucia, CSIC, Granada, Spain, the Scientific Support Office of the European Space Agency, Noordwijk, The Netherlands, the Instituto Nacional de Técnica Aeroespacial, Madrid, Spain, the Universidad Politécnica de Madrid, Spain, the Department of Physics and Astronomy of Uppsala University, Sweden, and the Institut für Datentechnik und Kommunikationsnetze der Technischen Universität Braunschweig, Germany. References: [1] Keller, H. U. et al.: OSIRIS The Scientific Camera System Onboard Rosetta, Space Sci. Rev., 128, pp. 433-506, 2007; [2] Vincent, J.-B. et al.: Are fractured cliffs the source of cometary dust jets? Insights from OSIRIS/Rosetta at 67P/Churyumov-Gerasimenko, A&A, 587:A14, 2016; [3] Pajola, M. et al.: Aswan site on comet 67P/Churyumov-Gerasimenko: Morphology, boulder evolution, and spectrophotometry, A&A, 592:A69, 2016; [4] Sierks, H. et al.: On the nucleus structure and activity of comet 67P/Churyumov-Gerasimenko, Science, 347, 2015; [5] Groussin, O. et al.: Gravitational slopes, geomorphology, and material strengths of the nucleus of comet 67P/Churyumov-Gerasimenko from OSIRIS observations, A&A, 583:A32, 2015; [6] https://launchpad.net/esys-particle

Controlling Laser Plasma Instabilities Using Temporal Bandwidths Under Shock Ignition Relevant Conditions

NASA Astrophysics Data System (ADS)

Tsung, Frank; Weaver, J.; Lehmberg, R.

2017-10-01

We are performing particle-in-cell simulations using the code OSIRIS to study the effects of laser plasma interactions in the presence of temporal bandwidth under plasma conditions relevant to experiments on the Nike laser with induced spatial incoherence (ISI). With ISI, the instantaneous laser intensity can be 3-4 times larger than the average intensity, leading to the excitation of additional TPD modes and producing electrons with larger angular spread. In our simulations, we observe that although ISI can increase the interaction regions for short bursts of time, time-averaged (over many pico-seconds) laser plasma interactions can be reduced by a factor of 2 in systems with sufficiently large bandwidths (where the inverse bandwidth is comparable with the linear growth time). We will quantify these effects and investigate higher dimensional effects such as laser speckles and the effects of Coulomb collisions. Work supported by NRL, NNSA, and NSF.

Role of liver fatty acid binding protein in hepatocellular injury: effect of CrPic treatment.

PubMed

Fan, Weijiang; Chen, Kun; Zheng, Guoqiang; Wang, Wenhang; Teng, Anguo; Liu, Anjun; Ming, Dongfeng; Yan, Peng

2013-07-01

This study was designed to investigate the molecular mechanisms of chromium picolinate (CrPic, Fig. 1) hepatoprotective activity from alloxan-induced hepatic injury. Diabetes is induced by alloxan-treatment concurrently with the hepatic injury in mice. In this study, we investigate the protective effect of CrPic treatment in hepatic injury and the signal role of liver fatty acid binding protein in early hepatocellular injury diagnostics. In this study, alanine aminotransferase (ALT; EC 2.6.1.2) and aspartate aminotransferase (AST; EC 2.6.1.1) levels in the alloxan group were higher 71% and 50%, respectively, than those of the control group (ALT: 14.51±0.74; AST: 22.60±0.69). The AST and ALT levels in CrPic group were of minimal difference compared to the control groups. Here, CrPic exhibited amelioration alloxan induced oxidative stress in mouse livers. A significant increase in liver fatty acid-binding protein (L-FABP) was observed, which indicates increased fatty acid utilization in liver tissue [1]. In this study, the mRNA levels of L-FABP increased in both the control (1.1 fold) and CrPic (0.78 fold) groups compared the alloxan group. These findings suggest that hepatic injury may be prevented by CrPic, and is a potential target for use in the treatment of early hepatic injury. Copyright © 2013 Elsevier Inc. All rights reserved.

Development of Spectral and Atomic Models for Diagnosing Energetic Particle Characteristics in Fast Ignition Experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

MacFarlane, Joseph J.; Golovkin, I. E.; Woodruff, P. R.

2009-08-07

This Final Report summarizes work performed under DOE STTR Phase II Grant No. DE-FG02-05ER86258 during the project period from August 2006 to August 2009. The project, “Development of Spectral and Atomic Models for Diagnosing Energetic Particle Characteristics in Fast Ignition Experiments,” was led by Prism Computational Sciences (Madison, WI), and involved collaboration with subcontractors University of Nevada-Reno and Voss Scientific (Albuquerque, NM). In this project, we have: Developed and implemented a multi-dimensional, multi-frequency radiation transport model in the LSP hybrid fluid-PIC (particle-in-cell) code [1,2]. Updated the LSP code to support the use of accurate equation-of-state (EOS) tables generated by Prism’smore » PROPACEOS [3] code to compute more accurate temperatures in high energy density physics (HEDP) plasmas. Updated LSP to support the use of Prism’s multi-frequency opacity tables. Generated equation of state and opacity data for LSP simulations for several materials being used in plasma jet experimental studies. Developed and implemented parallel processing techniques for the radiation physics algorithms in LSP. Benchmarked the new radiation transport and radiation physics algorithms in LSP and compared simulation results with analytic solutions and results from numerical radiation-hydrodynamics calculations. Performed simulations using Prism radiation physics codes to address issues related to radiative cooling and ionization dynamics in plasma jet experiments. Performed simulations to study the effects of radiation transport and radiation losses due to electrode contaminants in plasma jet experiments. Updated the LSP code to generate output using NetCDF to provide a better, more flexible interface to SPECT3D [4] in order to post-process LSP output. Updated the SPECT3D code to better support the post-processing of large-scale 2-D and 3-D datasets generated by simulation codes such as LSP. Updated atomic physics modeling to provide for more comprehensive and accurate atomic databases that feed into the radiation physics modeling (spectral simulations and opacity tables). Developed polarization spectroscopy modeling techniques suitable for diagnosing energetic particle characteristics in HEDP experiments. A description of these items is provided in this report. The above efforts lay the groundwork for utilizing the LSP and SPECT3D codes in providing simulation support for DOE-sponsored HEDP experiments, such as plasma jet and fast ignition physics experiments. We believe that taken together, the LSP and SPECT3D codes have unique capabilities for advancing our understanding of the physics of these HEDP plasmas. Based on conversations early in this project with our DOE program manager, Dr. Francis Thio, our efforts emphasized developing radiation physics and atomic modeling capabilities that can be utilized in the LSP PIC code, and performing radiation physics studies for plasma jets. A relatively minor component focused on the development of methods to diagnose energetic particle characteristics in short-pulse laser experiments related to fast ignition physics. The period of performance for the grant was extended by one year to August 2009 with a one-year no-cost extension, at the request of subcontractor University of Nevada-Reno.« less

Evaluation of the Parent-Implemented Communication Strategies (PiCS) Project Using the Multiattribute Utility (MAU) Approach

ERIC Educational Resources Information Center

Stoner, Julia B.; Meadan, Hedda; Angell, Maureen E.; Daczewitz, Marcus

2012-01-01

We conducted a multiattribute utility (MAU) evaluation to assess the Parent-Implemented Communication Strategies (PiCS) project which was funded by the Institute of Education Sciences (IES). In the PiCS project parents of young children with developmental disabilities are trained and coached in their homes on naturalistic and visual teaching…

Beam dynamics simulation of HEBT for the SSC-linac injector

NASA Astrophysics Data System (ADS)

Li, Xiao-Ni; Yuan, You-Jin; Xiao, Chen; He, Yuan; Wang, Zhi-Jun; Sheng, Li-Na

2012-11-01

The SSC-linac (a new injector for the Separated Sector Cyclotron) is being designed in the HIRFL (Heavy Ion Research Facility in Lanzhou) system to accelerate 238U34+ from 3.72 keV/u to 1.008 MeV/u. As a part of the SSC-linac injector, the HEBT (high energy beam transport) has been designed by using the TRACE-3D code and simulated by the 3D PIC (particle-in-cell) Track code. The total length of the HEBT is about 12 meters and a beam line of about 6 meters are shared with the exiting beam line of the HIRFL system. The simulation results show that the particles can be delivered efficiently in the HEBT and the particles at the exit of the HEBT well match the acceptance of the SSC for further acceleration. The dispersion is eliminated absolutely in the HEBT. The space-charge effect calculated by the Track code is inconspicuous. According to the simulation, more than 60 percent of the particles from the ion source can be transported into the acceptance of the SSC.

Water column profiles of particulate inorganic carbon in the northeast subarctic Pacific Ocean

NASA Astrophysics Data System (ADS)

Sutton, J. N.; Bishop, J. K.; Martinez, E. J.; Weiss, G. A.; Weiss, A.; Derr, A.; Strubhar, W.; Robert, M.; Wood, T.

2013-12-01

High resolution and real-time measurement of particulate inorganic carbon (PIC) content in seawater is necessary to improve our spatial and temporal understanding of marine carbon flux and the possible effects of ocean acidification on the biological pump. On four occasions since August 2012, we have mapped PIC distribution from surface to bottom at 26 stations along the IOS-Canada Line P transect from western Vancouver Island, BC, Canada to Ocean Station PAPA, 50N 145W using a prototype (PIC001) and a near-commercial quality (PIC008) optical birefringence sensor. The sensors are highly modified 6000m-rated WETLabs C-star transmissometers, which use a polarized laser beam and a cross-polarized receiver to measure photons emitted after passing through birefringent solids. At major stations along Line P (P2, P4, P8, P12, P16, P20, P26), one-liter rosette-collected calibration water samples were filtered through 0.45 μm Supor filters using a small-volume direct filtration system. These samples were analysed for acid-leachable particulate elements (with emphasis on Ca, Na, and Mg) by inductively coupled plasma mass spectrometry (ICPMS). ICPMS PIC was calculated as residual Ca after correction for seawater Ca using Na data. Here we report results for late summer (Aug. 2012) and winter (Feb. 2013). As expected, high levels of PIC (> 100 nmol L-1 to > 2000 nmol L-1) were found in surface waters but rapidly declined at depths greater than 200m and increased again in the nepheloid layer (>50 nmol L-1). Striking seasonal differences in PIC content and PIC profile shape were observed particularly at near shore stations P2, P4, P8 and P12. The results from this research, including sensor evolution and calibration performance, will be presented.

Effects of Chromium Picolinate on Vascular Reactivity and Cardiac Ischemia Reperfusion Injury in Spontaneously Hypertensive Rats

PubMed Central

Abebe, Worku; Liu, Jun Yao; Wimborne, Hereward; Mozaffari, Mahmood S.

2013-01-01

Chromium picolinate [Cr(pic)3] is a nutritional supplement widely promoted to exert beneficial metabolic effects in patients with type 2 diabetes/impaired glucose tolerance. Frequent comorbidities in these individuals include systemic hypertension, abnormal vascular function and ischemic heart disease but information on effects of the supplement on these aspects is sparse. Utilizing male spontaneously hypertensive rats (SHR), we examined potential impact of Cr(pic)3 on blood pressure, vascular reactivity and myocardial ischemia reperfusion injury (IRI). Dietary Cr(pic)3 supplementation (as 10 mg chromium/kg diet for 6 weeks) did not affect blood pressure of the SHR. Also, neither norepinephrine (NE) and potassium chloride (KCl)-induced contractility nor sodium nitroprusside (SNP)-induced relaxation of aortic smooth muscle from the SHR was altered by Cr(pic)3 treatment. However, Cr(pic)3 augmented endothelium-dependent relaxation of aortas, produced by acetylcholine (ACh), and this effect was abolished by N-nitro-L-arginine methyl ester (L-NAME) suggesting induction of nitric oxide (NO) production/release. Treatment with Cr(pic)3 did not affect baseline coronary flow rate and rate-pressure-product (RPP) or infarct size following regional IRI. Nonetheless, Cr(pic)3 treatment was associated with improved coronary flow and recovery of myocardial contractility and relaxation following ischemia reperfusion insult. In conclusion, dietary Cr(pic)3 treatment of SHR neither alters blood pressure nor vascular smooth muscle reactivity, but causes enhancement of endothelium-dependent vasorelaxation associated with NO production/release. Additionally, while the treatment does not affect infarct size, it improves functional recovery of the viable portion of the myocardium following IRI. PMID:20885007

Effects of chromium picolinate on vascular reactivity and cardiac ischemia-reperfusion injury in spontaneously hypertensive rats.

PubMed

Abebe, Worku; Liu, Jun Yao; Wimborne, Hereward; Mozaffari, Mahmood S

2010-01-01

Chromium picolinate [Cr(pic)(3)] is a nutritional supplement widely promoted to exert beneficial metabolic effects in patients with type 2 diabetes/impaired glucose tolerance. Frequent comorbidities in these individuals include systemic hypertension, abnormal vascular function and ischemic heart disease, but information on the effects of the supplement on these aspects is sparse. Utilizing male spontaneously hypertensive rats (SHR), we examined the potential impact of Cr(pic)(3) on blood pressure, vascular reactivity and myocardial ischemia-reperfusion injury (IRI). Dietary Cr(pic)(3) supplementation (as 10 mg chromium/kg diet for six weeks) did not affect blood pressure of the SHR. Also, neither norepinephrine (NE) and potassium chloride (KCl)-induced contractility nor sodium nitroprusside (SNP)-induced relaxation of aortic smooth muscle from the SHR was altered by Cr(pic)(3) treatment. However, Cr(pic)(3) augmented endothelium-dependent relaxation of aortas, produced by acetylcholine (ACh), and this effect was abolished by N-nitro-L-arginine methyl ester (L-NAME), suggesting induction of nitric oxide (NO) production/release. Treatment with Cr(pic)(3) did not affect baseline coronary flow rate and rate-pressure-product (RPP) or infarct size following regional IRI. Nonetheless, Cr(pic)(3) treatment was associated with improved coronary flow and recovery of myocardial contractility and relaxation following ischemia-reperfusion insult. In conclusion, dietary Cr(pic)(3) treatment of SHR alters neither blood pressure nor vascular smooth muscle reactivity but causes enhancement of endothelium-dependent vasorelaxation associated with NO production/release. Additionally, while the treatment does not affect infarct size, it improves functional recovery of the viable portion of the myocardium following IRI.

Freeing data through The Polar Information Commons

NASA Astrophysics Data System (ADS)

de Bruin, T.; Chen, R. S.; Parsons, M. A.; Carlson, D. J.; Cass, K.; Finney, K.; Wilbanks, J.; Jochum, K.

2010-12-01

The polar regions are changing rapidly with dramatic global effect. Wise management of resources, improved decision support, and effective international cooperation on resource and geopolitical issues require deeper understanding and better prediction of these changes. Unfortunately, polar data and information remain scattered, scarce, and sporadic. Inspired by the Antarctic Treaty of 1959 that established the Antarctic as a global commons to be used only for peaceful purposes and scientific research, we assert that data and information about the polar regions are themselves “public goods” that should be shared ethically and with minimal constraint. ICSU’s Committee on Data (CODATA) therefore started the Polar Information Commons (PIC) as an open, virtual repository for vital scientific data and information. The PIC provides a shared, community-based cyber-infrastructure fostering innovation, improving scientific efficiency, and encouraging participation in polar research, education, planning, and management. The PIC builds on the legacy of the International Polar Year (IPY), providing a long-term framework for access to and preservation of both existing and future data and information about the polar regions. Rapid change demands rapid data access. The PIC system enables scientists to quickly expose their data to the world and share them through open protocols on the Internet. A PIC digital label will alert users and data centers to new polar data and ensure that usage rights are clear. The PIC utilizes the Science Commons Protocol for Implementing Open Access Data, which promotes open data access through the public domain coupled with community norms of practice to ensure use of data in a fair and equitable manner. A set of PIC norms has been developed in consultation with key polar data organizations and other stakeholders. We welcome inputs from the broad science community as we further develop and refine the PIC approach and move ahead with implementation.

Stable carbon isotope signals in particulate organic and inorganic carbon of coccolithophores - A numerical model study for Emiliania huxleyi.

PubMed

Holtz, Lena-Maria; Wolf-Gladrow, Dieter; Thoms, Silke

2017-05-07

A recent numerical cell model, which explains observed light and carbonate system effects on particulate organic and inorganic carbon (POC and PIC) production rates under the assumption of internal pH homeostasis, is extended for stable carbon isotopes ( 12 C, 13 C). Aim of the present study is to mechanistically understand the stable carbon isotopic fractionation signal (ε) in POC and PIC and furthermore the vital effect(s) included in measured ε PIC values. The virtual cell is divided into four compartments, for each of which the 12 C as well as the 13 C carbonate system kinetics are implemented. The compartments are connected to each other via trans-membrane fluxes. In contrast to existing carbon fractionation models, the presented model calculates the disequilibrium state for both carbonate systems and for each compartment. It furthermore calculates POC and PIC production rates as well as ε POC and ε PIC as a function of given light conditions and the compositions of the external carbonate system. Measured POC and PIC production rates as well as ε PIC values are reproduced well by the model (comparison with literature data). The observed light effect on ε POC (increase of ε POC with increasing light intensities), however, is not reproduced by the basic model set-up, which is solely based on RubisCO fractionation. When extending the latter set-up by assuming that biological fractionation includes further carbon fractionation steps besides the one of RubisCO, the observed light effect on ε POC is also reproduced. By means of the extended model version, four different vital effects that superimpose each other in a real cell can be detected. Finally, we discuss potential limitations of the ε PIC proxy. Copyright © 2017 Elsevier Ltd. All rights reserved.

The OSIRIS-REx laser altimeter (OLA): Development progress

NASA Astrophysics Data System (ADS)

Daly, M.; Barnouin, O.; Johnson, C.; Bierhaus, E.; Seabrook, J.; Dickinson, C.; Haltigin, T.; Gaudreau, D.; Brunet, C.; Cunningham, G.; Lauretta, D.; Boynton, W.; Beshore, E.

2014-07-01

Introduction: The NASA New Frontiers Origins Spectral Interpretation Resource Identification Security Regolith Explorer (OSIRIS-REx) mission will be the first to sample the B-type asteroid (101955) Bennu [1]. This asteroid is thought to be primitive and carbonaceous, and is probably closely related to CI and/or CM meteorites [2]. The OSIRIS-REx mission hopes to better understand both the physical and geochemical origin and evolution of carbonaceous asteroids through its investigation of Bennu. The OSIRIS-REx spacecraft will launch in September 2016, and arrive at Bennu two years later. The Canadian Space Agency is contributing a scanning lidar system known as the OSIRIS-REx Laser Altimeter (OLA), to the OSIRIS-REx Mission. The OLA instrument is part of suite of onboard instruments [3] including cameras (OCAMS) [4], a visible and near- infrared spectrometer (OVIRS) [5], a thermal emission spectrometer (OTES), and an X-ray imaging spectrometer (REXIS) [6]. OLA Objectives: The OLA instrument has a suite of scientific and mission operations purposes. At a global scale, it will update the shape and mass of Bennu to provide insights on the geological origin and evolution of Bennu, by, for example, further refining constraints on its bulk density. With a carefully undertaken geodesy campaign, OLA-based precision ranges, constraints from radio science (2-way tracking) data and stereo OCAMS images, it will yield broad-scale, quantitative constraints on any internal heterogeneity of Bennu and hence provide further clues to Bennu's origin and subsequent collisional evolution. OLA-derived global asteroid maps of slopes, elevation relative to the asteroid geoid, and vertical roughness will provide quantitative insights on how local-regional surfaces on Bennu evolved subsequent to the formation of the asteroid. In addition, OLA data and derived products support the assessment of the safety and sampleability of potential sample sites. At the sample-site scale, the OLA instrument will provide detailed information on the geological and geophysical processes which influence the surface regolith at scales relevant to the samples that will be collected. High resolution (meter-scale) spatial measurements of surface topographic slopes, center-of-mass referenced elevation, and vertical roughness within the sample ellipse will provide quantitative data on regolith processes such as surface granular flows that could have displaced the regolith sampled by OSIRIS-REx spacecraft. The OLA system will also be responsible for assessing hazards at any proposed sample site. Specifically, the OLA system will measure the slope distribution within the sample ellipse and characterize backscatter roughness at or below the scale of the OLA spot size. Technical Specifications: The completed OLA instrument is expected to achieve all these objectives through its specifications that are based on the characteristics of Bennu and operational considerations: Maximum Operational Range, 7.5 km; Minimum Operational Range, 0.150 km; Range Accuracy, 5--20 cm (range dependent); Range Resolution, <4 cm; Scanner Field of Regard, ±10 deg. (each axis); Laser Spot Size (on surface), 0.015--2 m (range dependent). Progress To-date: A prototype of the OLA system has been developed and successfully tested. Results from this testing will be presented and compared with the instrument requirements. Simulated OLA datasets will be presented along with the first engineering model hardware and test results.

Copper Import into the Mitochondrial Matrix in Saccharomyces cerevisiae Is Mediated by Pic2, a Mitochondrial Carrier Family Protein*

PubMed Central

Vest, Katherine E.; Leary, Scot C.; Winge, Dennis R.; Cobine, Paul A.

2013-01-01

Saccharomyces cerevisiae must import copper into the mitochondrial matrix for eventual assembly of cytochrome c oxidase. This copper is bound to an anionic fluorescent molecule known as the copper ligand (CuL). Here, we identify for the first time a mitochondrial carrier family protein capable of importing copper into the matrix. In vitro transport of the CuL into the mitochondrial matrix was saturable and temperature-dependent. Strains with a deletion of PIC2 grew poorly on copper-deficient non-fermentable medium supplemented with silver and under respiratory conditions when challenged with a matrix-targeted copper competitor. Mitochondria from pic2Δ cells had lower total mitochondrial copper and exhibited a decreased capacity for copper uptake. Heterologous expression of Pic2 in Lactococcus lactis significantly enhanced CuL transport into these cells. Therefore, we propose a novel role for Pic2 in copper import into mitochondria. PMID:23846699

Copper import into the mitochondrial matrix in Saccharomyces cerevisiae is mediated by Pic2, a mitochondrial carrier family protein.

PubMed

Vest, Katherine E; Leary, Scot C; Winge, Dennis R; Cobine, Paul A

2013-08-16

Saccharomyces cerevisiae must import copper into the mitochondrial matrix for eventual assembly of cytochrome c oxidase. This copper is bound to an anionic fluorescent molecule known as the copper ligand (CuL). Here, we identify for the first time a mitochondrial carrier family protein capable of importing copper into the matrix. In vitro transport of the CuL into the mitochondrial matrix was saturable and temperature-dependent. Strains with a deletion of PIC2 grew poorly on copper-deficient non-fermentable medium supplemented with silver and under respiratory conditions when challenged with a matrix-targeted copper competitor. Mitochondria from pic2Δ cells had lower total mitochondrial copper and exhibited a decreased capacity for copper uptake. Heterologous expression of Pic2 in Lactococcus lactis significantly enhanced CuL transport into these cells. Therefore, we propose a novel role for Pic2 in copper import into mitochondria.

Multirate Particle-in-Cell Time Integration Techniques of Vlasov-Maxwell Equations for Collisionless Kinetic Plasma Simulations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Guangye; Chacon, Luis; Knoll, Dana Alan

2015-07-31

A multi-rate PIC formulation was developed that employs large timesteps for slow field evolution, and small (adaptive) timesteps for particle orbit integrations. Implementation is based on a JFNK solver with nonlinear elimination and moment preconditioning. The approach is free of numerical instabilities (ω peΔt >>1, and Δx >> λ D), and requires many fewer dofs (vs. explicit PIC) for comparable accuracy in challenging problems. Significant gains (vs. conventional explicit PIC) may be possible for large scale simulations. The paper is organized as follows: Vlasov-Maxwell Particle-in-cell (PIC) methods for plasmas; Explicit, semi-implicit, and implicit time integrations; Implicit PIC formulation (Jacobian-Free Newton-Krylovmore » (JFNK) with nonlinear elimination allows different treatments of disparate scales, discrete conservation properties (energy, charge, canonical momentum, etc.)); Some numerical examples; and Summary.« less

Interferometric imaging using Si3N4 photonic integrated circuits for a SPIDER imager.

PubMed

Su, Tiehui; Liu, Guangyao; Badham, Katherine E; Thurman, Samuel T; Kendrick, Richard L; Duncan, Alan; Wuchenich, Danielle; Ogden, Chad; Chriqui, Guy; Feng, Shaoqi; Chun, Jaeyi; Lai, Weicheng; Yoo, S J B

2018-05-14

This paper reports design, fabrication, and experimental demonstration of a silicon nitride photonic integrated circuit (PIC). The PIC is capable of conducting one-dimensional interferometric imaging with twelve baselines near λ = 1100-1600 nm. The PIC consists of twelve waveguide pairs, each leading to a multi-mode interferometer (MMI) that forms broadband interference fringes or each corresponding pair of the waveguides. Then an 18 channel arrayed waveguide grating (AWG) separates the combined signal into 18 signals of different wavelengths. A total of 103 sets of fringes are collected by the detector array at the output of the PIC. We keep the optical path difference (OPD) of each interferometer baseline to within 1 µm to maximize the visibility of the interference measurement. We also constructed a testbed to utilize the PIC for two-dimension complex visibility measurement with various targets. The experiment shows reconstructed images in good agreement with theoretical predictions.

Functional interplay between Mediator and TFIIB in preinitiation complex assembly in relation to promoter architecture

PubMed Central

Eychenne, Thomas; Novikova, Elizaveta; Barrault, Marie-Bénédicte; Alibert, Olivier; Boschiero, Claire; Peixeiro, Nuno; Cornu, David; Redeker, Virginie; Kuras, Laurent; Nicolas, Pierre; Werner, Michel; Soutourina, Julie

2016-01-01

Mediator is a large coregulator complex conserved from yeast to humans and involved in many human diseases, including cancers. Together with general transcription factors, it stimulates preinitiation complex (PIC) formation and activates RNA polymerase II (Pol II) transcription. In this study, we analyzed how Mediator acts in PIC assembly using in vivo, in vitro, and in silico approaches. We revealed an essential function of the Mediator middle module exerted through its Med10 subunit, implicating a key interaction between Mediator and TFIIB. We showed that this Mediator–TFIIB link has a global role on PIC assembly genome-wide. Moreover, the amplitude of Mediator's effect on PIC formation is gene-dependent and is related to the promoter architecture in terms of TATA elements, nucleosome occupancy, and dynamics. This study thus provides mechanistic insights into the coordinated function of Mediator and TFIIB in PIC assembly in different chromatin contexts. PMID:27688401

PIC Simulations of Hypersonic Plasma Instabilities

NASA Astrophysics Data System (ADS)

Niehoff, D.; Ashour-Abdalla, M.; Niemann, C.; Decyk, V.; Schriver, D.; Clark, E.

2013-12-01

The plasma sheaths formed around hypersonic aircraft (Mach number, M > 10) are relatively unexplored and of interest today to both further the development of new technologies and solve long-standing engineering problems. Both laboratory experiments and analytical/numerical modeling are required to advance the understanding of these systems; it is advantageous to perform these tasks in tandem. There has already been some work done to study these plasmas by experiments that create a rapidly expanding plasma through ablation of a target with a laser. In combination with a preformed magnetic field, this configuration leads to a magnetic "bubble" formed behind the front as particles travel at about Mach 30 away from the target. Furthermore, the experiment was able to show the generation of fast electrons which could be due to instabilities on electron scales. To explore this, future experiments will have more accurate diagnostics capable of observing time- and length-scales below typical ion scales, but simulations are a useful tool to explore these plasma conditions theoretically. Particle in Cell (PIC) simulations are necessary when phenomena are expected to be observed at these scales, and also have the advantage of being fully kinetic with no fluid approximations. However, if the scales of the problem are not significantly below the ion scales, then the initialization of the PIC simulation must be very carefully engineered to avoid unnecessary computation and to select the minimum window where structures of interest can be studied. One method of doing this is to seed the simulation with either experiment or ion-scale simulation results. Previous experiments suggest that a useful configuration for studying hypersonic plasma configurations is a ring of particles rapidly expanding transverse to an external magnetic field, which has been simulated on the ion scale with an ion-hybrid code. This suggests that the PIC simulation should have an equivalent configuration; however, modeling a plasma expanding radially in every direction is computationally expensive. In order to reduce the computational expense, we use a radial density profile from the hybrid simulation results to seed a self-consistent PIC simulation in one direction (x), while creating a current in the direction (y) transverse to both the drift velocity and the magnetic field (z) to create the magnetic bubble observed in experiment. The simulation will be run in two spatial dimensions but retain three velocity dimensions, and the results will be used to explore the growth of micro-instabilities present in hypersonic plasmas in the high-density region as it moves through the simulation box. This will still require a significantly large box in order to compare with experiment, as the experiments are being performed over distances of 104 λDe and durations of 105 ωpe-1.

Touch And Go Camera System (TAGCAMS) for the OSIRIS-REx Asteroid Sample Return Mission

NASA Astrophysics Data System (ADS)

Bos, B. J.; Ravine, M. A.; Caplinger, M.; Schaffner, J. A.; Ladewig, J. V.; Olds, R. D.; Norman, C. D.; Huish, D.; Hughes, M.; Anderson, S. K.; Lorenz, D. A.; May, A.; Jackman, C. D.; Nelson, D.; Moreau, M.; Kubitschek, D.; Getzandanner, K.; Gordon, K. E.; Eberhardt, A.; Lauretta, D. S.

2018-02-01

NASA's OSIRIS-REx asteroid sample return mission spacecraft includes the Touch And Go Camera System (TAGCAMS) three camera-head instrument. The purpose of TAGCAMS is to provide imagery during the mission to facilitate navigation to the target asteroid, confirm acquisition of the asteroid sample, and document asteroid sample stowage. The cameras were designed and constructed by Malin Space Science Systems (MSSS) based on requirements developed by Lockheed Martin and NASA. All three of the cameras are mounted to the spacecraft nadir deck and provide images in the visible part of the spectrum, 400-700 nm. Two of the TAGCAMS cameras, NavCam 1 and NavCam 2, serve as fully redundant navigation cameras to support optical navigation and natural feature tracking. Their boresights are aligned in the nadir direction with small angular offsets for operational convenience. The third TAGCAMS camera, StowCam, provides imagery to assist with and confirm proper stowage of the asteroid sample. Its boresight is pointed at the OSIRIS-REx sample return capsule located on the spacecraft deck. All three cameras have at their heart a 2592 × 1944 pixel complementary metal oxide semiconductor (CMOS) detector array that provides up to 12-bit pixel depth. All cameras also share the same lens design and a camera field of view of roughly 44° × 32° with a pixel scale of 0.28 mrad/pixel. The StowCam lens is focused to image features on the spacecraft deck, while both NavCam lens focus positions are optimized for imaging at infinity. A brief description of the TAGCAMS instrument and how it is used to support critical OSIRIS-REx operations is provided.

Revised Correlation between Odin/OSIRIS PMC Properties and Coincident TIMED/SABER Mesospheric Temperatures

NASA Technical Reports Server (NTRS)

Feofilov, A. G.; Petelina, S V.; Kutepov, A. A.; Pesnell, W. D.; Goldberg, R. A.; Llewellyn, E. J.; Russell, J. M.

2006-01-01

The Optical Spectrograph and Infrared Imaging System (OSIRIS) instrument on board the Odin satellite detects Polar Mesospheric Clouds (PMCs) through the enhancement in the limb scattered solar radiance. The Sounding of the Atmosphere using the Broadband Emission Radiometry (SABER) instrument on board the TIMED satellite is a limb scanning infrared radiometer that measures temperature and vertical profiles and energetic parameters for minor constituents in the mesosphere and lower thermosphere. The combination of OSIRIS and SABER data has been previously used to statistically derive thermal conditions for PMC existence [Petelina et al., 2005]. In this work, we employ the simultaneous common volume measurements of PMCs by OSIRIS and temperature profiles measured by SABER for the Northern Hemisphere summers of 2002-2005 and corrected in the polar region by accounting for the vibrational-vibrational energy exchange among the CO2 isotopes [Kutepov et al., 2006]. For each of 20 coincidences identified within plus or minus 1 degree latitude, plus or minus 2 degrees longitude and less than 1 hour time the frost point temperatures were calculated using the corresponding SABER temperature profile and water vapor densities of 1,3, and 10 ppmv. We found that the PMC presence and brightness correlated only with the temperature threshold that corresponds to the frost point. The absolute value of the temperature below the frost point, however, didn't play a significant role in the intensity of PMC signal for the majority of selected coincidences. The presence of several bright clouds at temperatures above the frost point is obviously related to the limitation of the limb geometry when some near- or far-field PMCs located at higher (and warmer) altitudes appear to be at lower altitudes.

Revised Correlation between Odin/OSIRIS PMC Properties and Coincident TIMED/SABER Mesospheric Temperatures

NASA Technical Reports Server (NTRS)

Feofilov, A. G.; Petelina, S. V.; Kutepov, A. A.; Pesnell, W. D.; Goldberg, R. A.; Llewellyn, E. J.; Russell, J. M.

2006-01-01

The Optical Spectrograph and Infrared Imaging System (OSIRIS) instrument on board the Odin satellite detects Polar Mesospheric Clouds (PMCs) through the enhancement in the limb-scattered solar radiance. The Sounding of the Atmosphere using the Broadband Emission Radiometry (SABER) instrument on board the TIMED satellite is a limb scanning infrared radiometer that measures temperature and vertical profiles and energetic parameters for minor constituents in the mesosphere and lower thermosphere. The combination of OSIRIS and SABER data has been previously used to statistically derive thermal conditions for PMC existence [Petelina et al., 2005]. a, A.A. Kutepov, W.D. Pesnell, In this work, we employ the simultaneous common volume measurements of PMCs by OSIRIS and temperature profiles measured by SABER for the Northern Hemisphere summers of 2002-2005 and corrected in the polar region by accounting for the vibrational-vibrational energy exchange among the CO2 isotopes [Kutepov et al., 2006]. For each of 20 coincidences identified within plus or minus 1 degree latitude, plus or minus 2 degrees longitude and less than 1 hour time the frost point temperatures were calculated using the corresponding SABER temperature profile and water vapor densities of 1,3, and 10 ppmv. We found that the PMC presence and brightness correlated only with the temperature threshold that corresponds to the frost point. The absolute value of the temperature below the frost point, however, didn't play a significant role in the intensity of PMC signal for the majority of selected coincidences. The presence of several bright clouds at temperatures above the frost point is obviously related to the limitation of the limb geometry when some near- or far-field PMCs located at higher (and warmer) altitudes appear to be at lower altitudes.

A new hybrid code (CHIEF) implementing the inertial electron fluid equation without approximation

NASA Astrophysics Data System (ADS)

Muñoz, P. A.; Jain, N.; Kilian, P.; Büchner, J.

2018-03-01

We present a new hybrid algorithm implemented in the code CHIEF (Code Hybrid with Inertial Electron Fluid) for simulations of electron-ion plasmas. The algorithm treats the ions kinetically, modeled by the Particle-in-Cell (PiC) method, and electrons as an inertial fluid, modeled by electron fluid equations without any of the approximations used in most of the other hybrid codes with an inertial electron fluid. This kind of code is appropriate to model a large variety of quasineutral plasma phenomena where the electron inertia and/or ion kinetic effects are relevant. We present here the governing equations of the model, how these are discretized and implemented numerically, as well as six test problems to validate our numerical approach. Our chosen test problems, where the electron inertia and ion kinetic effects play the essential role, are: 0) Excitation of parallel eigenmodes to check numerical convergence and stability, 1) parallel (to a background magnetic field) propagating electromagnetic waves, 2) perpendicular propagating electrostatic waves (ion Bernstein modes), 3) ion beam right-hand instability (resonant and non-resonant), 4) ion Landau damping, 5) ion firehose instability, and 6) 2D oblique ion firehose instability. Our results reproduce successfully the predictions of linear and non-linear theory for all these problems, validating our code. All properties of this hybrid code make it ideal to study multi-scale phenomena between electron and ion scales such as collisionless shocks, magnetic reconnection and kinetic plasma turbulence in the dissipation range above the electron scales.

Electromagnetic PIC modeling with a background gas

NASA Astrophysics Data System (ADS)

Verboncoeur, J. P.; Cooperberg, D.

1997-02-01

Modeling the interaction of relativistic electromagnetic plasmas with a background gas is described. The timescales range over many orders of magnitude, from the electromagnetic Courant condition (˜10-12 sec) to electron-neutral collision times (˜10-7 sec) to ion transit times (˜10-5 sec). For this work, the traditional Monte Carlo algorithm [1] is described for relativistic electrons. Subcycling is employed to improve efficiency, and smoothing is employed to reduce particle noise. Applications include plasma-focused electron guns, gas-filled microwave tubes, surface wave discharges driven at microwave frequencies, and electron-cyclotron resonance discharges. The method is implemented in the OOPIC code [2].

Emittance Growth in the DARHT-II Linear Induction Accelerator

NASA Astrophysics Data System (ADS)

Ekdahl, Carl; Carlson, Carl A.; Frayer, Daniel K.; McCuistian, B. Trent; Mostrom, Christopher B.; Schulze, Martin E.; Thoma, Carsten H.

2017-11-01

The Dual-Axis Radiographic Hydrotest (DARHT) facility uses bremsstrahlung radiation source spots produced by the focused electron beams from two linear induction accelerators (LIAs) to radiograph large hydrodynamic experiments driven by high explosives. Radiographic resolution is determined by the size of the source spot, and beam emittance is the ultimate limitation to spot size. Some of the possible causes for the emittance growth in the DARHT LIA have been investigated using particle-in-cell (PIC) codes, and are discussed in this article. The results suggest that the most likely source of emittance growth is a mismatch of the beam to the magnetic transport, which can cause beam halo.

Characterization of plasma wake excitation and particle trapping in the nonlinear bubble regime

NASA Astrophysics Data System (ADS)

Benedetti, Carlo; Schroeder, Carl; Esarey, Eric; Leemans, Wim

2010-11-01

We investigate the excitation of nonlinear wake (bubble) formation by an ultra-short (kpL ˜2), intense (e Alaser/mc^2 > 2) laser pulse interacting with an underdense plasma. A detailed analysis of particle orbits in the wakefield is performed by using reduced analytical models and numerical simulations performed with the 2D cylindrical, envelope, ponderomotive, hybrid PIC/fluid code INF&RNO, recently developed at LBNL. In particular we study the requirements for injection and/or trapping of background plasma electrons in the nonlinear wake. Characterization of the phase-space properties of the injected particle bunch will also be discussed.

Planning, Management and Evaluation: Realizing PIC Potential. Private Industry Council Guide. Working Draft.

ERIC Educational Resources Information Center

National Alliance of Business, Inc., Washington, DC.

This Planning, Management, and Evaluation (PME) guide was developed by the National Alliance of Business as part of its program of management assistance for Private Industry Councils (PICs). The guide is a tool which PICs can use to improve their capability to plan, manage, and evaluate the programs which they administer, and to establish locally…

PICs, TECs and LECs: Lessons to Be Learnt from the Differences between the USA Private Industry Councils and Britain's Training and Enterprise Councils.

ERIC Educational Resources Information Center

Bennett, Robert J.

1994-01-01

Comparison of Britain's Training and Enterprise Councils/Local Enterprise Companies with the United States' Private Industry Councils (PICs) shows common problems: inadequate financing, labor market fragmentation, staff turnover, and lack of national strategy. PICs have a clearer mission and greater success in developing partnerships with local…

Private Industry Councils: Examining Their Mission under the Job Training Partnership Act. Special Report Number 35.

ERIC Educational Resources Information Center

National Commission for Employment Policy (DOL), Washington, DC.

A number of findings and recommendations regarding the mission of Private Industry Councils (PICs) under the Job Training Partnership ACT (JTPA) were developed based on information collected in several ways: a focus group of PICs, roundtable discussions held nationwide with staff from nearly 100 PICs in 45 states, and canvasses of more than 200…

Accelerating a Particle-in-Cell Simulation Using a Hybrid Counting Sort

NASA Astrophysics Data System (ADS)

Bowers, K. J.

2001-11-01

In this article, performance limitations of the particle advance in a particle-in-cell (PIC) simulation are discussed. It is shown that the memory subsystem and cache-thrashing severely limit the speed of such simulations. Methods to implement a PIC simulation under such conditions are explored. An algorithm based on a counting sort is developed which effectively eliminates PIC simulation cache thrashing. Sustained performance gains of 40 to 70 percent are measured on commodity workstations for a minimal 2d2v electrostatic PIC simulation. More complete simulations are expected to have even better results as larger simulations are usually even more memory subsystem limited.

Library services and user satisfaction in developing countries: a case study.

PubMed

Mairaj, Muhammad Ijaz; Naseer, Mirza Muhammad

2013-12-01

Punjab Institute of Cardiology (PIC) is a recognised teaching hospital for cardiac care in the Punjab province of Pakistan. PIC has established a library to fulfil the research and information needs of health care professionals. This study aims to evaluate the satisfaction of users with the services of PIC library. A purposive sample of 15 health care professionals was selected. A semistructured interview technique based on an interview guide was used for collection of data. The data were qualitatively analysed using a thematic approach. Users of PIC library were satisfied with the library collection, organisation, reference and circulation services, staff attitudes, cooling and heating. They were concerned about library space, hours, furniture and environment, and suggested more availability of electronic library services, newer collections, better Internet access and comfortable furniture. The study proved useful to investigate users' satisfaction with the services of PIC library. It concludes that the PIC library should maintain and strengthen the services with which users are satisfied, and improve those about which they are concerned. The study will be useful to libraries in other developing countries for improvement in their services. © 2013 The authors. Health Information and Libraries Journal © 2013 Health Libraries Group.

Chromium picolinate supplementation in women: effects on body weight, composition, and iron status.

PubMed

Lukaski, Henry C; Siders, William A; Penland, James G

2007-03-01

This study tested the hypothesis that supplementation of chromium picolinate (CrPic), 200 microg Cr/d, compared with an equivalent amount of picolinic acid (1720 microg) in CrPic and placebo, decreases body weight, alters body composition, and reduces iron status of women fed diets of constant energy and nutrients. We fed 83 women nutritionally balanced diets, used anthropometry and dual x-ray absorptiometry to assess body composition, and measured serum and urinary Cr and biochemical indicators of iron status before and serially every 4 wk for 12 wk in a double-blind, randomized trial. CrPic supplementation increased (P < 0.0001) serum Cr concentration and urinary Cr excretion compared with picolinic acid and placebo. CrPic did not affect body weight or fat, although all groups lost (P < 0.05) weight and fat; it did not affect fat-free, mineral-free mass or measurements of iron status. Under conditions of controlled energy intake, CrPic supplementation of women did not independently influence body weight or composition or iron status. Thus, claims that supplementation of 200 microg of Cr as CrPic promotes weight loss and body composition changes are not supported.

Chromium picolinate induced apoptosis of lymphocytes and the signaling mechanisms thereof

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jana, Mahadevan; Rajaram, Anantanarayanan; Rajaram, Rama

2009-06-15

Cr(III)(picolinate){sub 3} [Cr(III)(pic){sub 3}] is currently used as a nutritional supplement and for treating Type-2 diabetes. The effect of Cr(III)(pic){sub 3} uptake in peripheral blood lymphocytes is investigated in this study. From the cytotoxicity data, DNA fragmentation pattern, Annexin V staining, TUNEL positivity and the ultrastructural characteristics such as chromatin condensation and formation of apoptotic bodies, it is clear that Cr(III)(pic){sub 3} induces a concentration dependent apoptosis. It is shown that reactive oxygen species (ROS) produced by treatment with Cr(III)(pic){sub 3} leads to apoptosis, since we find that pretreatment with N-acetyl cysteine inhibits the process. Using Western blotting technique andmore » fluorescence measurements, the downstream signaling molecules have also been identified. Cr(III)(pic){sub 3} treatment leads to collapse of the mitochondrial membrane potential, Bax expression, increase in cytosolic cytochrome c content and active caspase-3 and DNA fragmentation and all these manifestations are reduced by pretreating the lymphocytes with N-acetyl cysteine. Thus, it is shown that Cr(III)(pic){sub 3} is cytotoxic to lymphocytes with ROS and mitochondrial events playing a role in bringing about apoptosis.« less

Characterization of punctate inner choroidopathy using enhanced depth imaging optical coherence tomography.

PubMed

Zarranz-Ventura, Javier; Sim, Dawn A; Keane, Pearse A; Patel, Praveen J; Westcott, Mark C; Lee, Richard W; Tufail, Adnan; Pavesio, Carlos E

2014-09-01

To perform qualitative and quantitative analyses of retinal and choroidal morphology in patients with punctate inner choroidopathy (PIC) using enhanced depth imaging optical coherence tomography (EDI-OCT). Cross-sectional, consecutive series. A total of 2242 patients attending 2 tertiary referral uveitis clinics at Moorfields Eye Hospital were screened; 46 patients with PIC diagnosis were identified, and 35 eyes (35 patients) had clinically inactive PIC had EDI-OCT images that met the inclusion criteria. Punctate inner choroidopathy lesions were qualitatively assessed for retinal features, such as (1) focal elevation of the retinal pigment epithelium (RPE), (2) focal atrophy of the outer retina/RPE, and (3) presence of sub-RPE hyperreflective deposits and choroidal features: (a) presence of focal hyperreflective dots in the inner choroid and (b) focal thinning of the choroid adjacent to PIC lesions. Quantitative analyses of the retina, choroid, and choroidal sublayers were performed, and associations with clinical and demographic data were examined. Prevalence of each lesion pattern and thickness of retinal and choroidal layers. A total of 90 discrete PIC lesions were captured; 46.6% of PIC lesions consisted of focal atrophy of the outer retina and RPE; 34.4% consisted of sub-RPE hyperreflective deposits; and 18.8% consisted of localized RPE elevation with underlying hyporeflective space. Focal hyperreflective dots were seen in the inner choroid of 68.5% of patients, with 17.1% of eyes presenting focal choroidal thinning underlying PIC lesions. By excluding high myopes, patients with "atypical" PIC had reduced retinal thickness compared with patients with "typical" PIC (246.65±30.2 vs. 270.05±24.6 μm; P = 0.04), and greater disease duration was associated with decreases in retinal thickness (r = -0.53; P = 0.01). A significant correlation was observed between best-corrected visual acuity and foveal retinal thickness (r = -0.40; P = 0.03). In a large series of patients with clinically inactive PIC, one fifth of the lesions analyzed revealed RPE elevation with underlying hyporeflective space, described before as a sign of activity and suggesting subclinical inflammation. Retinal thickness seems to be associated with disease type and duration of disease in non-highly myopic eyes. Improved visualization of the inner choroid using EDI-OCT may allow noninvasive assessment of inflammatory status. Copyright © 2014 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

Body mass index is a practical preoperative nutritional index for postoperative infectious complications after intestinal resection in patients with Crohn's disease

PubMed Central

Zhu, Yibin; Zhou, Wei; Qi, Weilin; Liu, Wei; Chen, Mingyu; Zhu, Hepan; Xiang, Jianjian; Xie, Qingwen; Chen, Pengpeng

2017-01-01

Abstract The patients with Crohn's disease (CD) are often accompanied with nutritional deficiencies. Compared with other intestinal benign disease, patients with CD have the higher risk of developing postoperative complications following intestinal resection. The aim of this study was to investigate the risk factors for postoperative infectious complications (PICs) after intestinal resection for CD, as well as search a practical preoperative nutritional index for PICs in patients with CD. A total of 122 patients who underwent intestinal resection for CD during 2011 to 2015 were retrospectively analyzed. After operation, 28 (22.95%) patients experienced PICs. Compared with the non-PICs group, the patients with PICs have the lower preoperative body mass index (BMI) (16.96 ± 2.33 vs 19.53 ± 2.49 kg/m2, P < .001), lower albumin (ALB) (33.64 ± 5.58 vs 36.55 ± 5.69 g/L, P = .013), higher C-reactive protein (CRP) level (30.44 ± 37.06 vs 15.99 ± 33.30 mg/L, P = .052), and longer hospital stay (22.64 ± 9.93 vs 8.90 ± 4.32 days, P < .001). By analyzing the receiver-operating characteristic (ROC) curve, BMI have better value in predicting the occurrence of PICs than ALB. The areas under the ROC curves of BMI for PICs was 0.784 (95% confidence interval 0.690–0.878, P < .001) with an optimal diagnostic cut-off value of 17.5 kg/m2. In the univariate and multivariate analysis, BMI < 17.5 kg/m2 (P = .001), ALB < 33.6 g/L (P = .024), CRP ≥ 10 mg/L (P = .026) were risk factors for PICs. Patients with a lower preoperative BMI (BMI < 17.5 kg/m2) had a 7.35 times greater risk of PICs. Therefore, preoperative BMI could be regarded as a practical preoperative nutritional index for evaluating the nutritional preparation sufficiency before CD operations. Preoperative treatment with the aim of reducing CRP level and improving the patient's nutritional status may be helpful to reduce the rate of PICs. PMID:28591060

Impact of the Quality of Bowel Cleansing on the Efficacy of Colonic Cancer Screening: A Prospective, Randomized, Blinded Study

PubMed Central

2015-01-01

Objectives Efficacy of two low volume bowel cleansing preparations, polyethylene glycol plus ascorbate (PEG+Asc) and sodium picosulfate/magnesium citrate (NaPic/MgCit), were compared for polyp and adenoma detection rate (PDR and ADR) and overall cleansing ability. Primary endpoint was PDR (the number of patients with ≥1 polypoid or flat lesion recorded by the colonoscopist). Methods Diagnostic, surveillance or screening colonoscopy patients were enrolled into this investigator-blinded, multi-center Phase IV study and randomized 1:1 to receive PEG+Asc (administered the evening before and the morning of colonoscopy, per label) or NaPic/MgCit (administered in the morning and afternoon the day before colonoscopy, per label). The blinded colonoscopist documented any lesion and assessed cleansing quality (Harefield Cleansing Scale). Results Of 394 patients who completed the study, 393 (PEG+Asc, N=200; NaPic/MgCit, N=193) had a colonoscopy. Overall PDR for PEG+Asc versus NaPic/MgCit was 51.5% versus 44.0%, p=0.139. PDR and ADR on the right side of the bowel were significantly higher with PEG+Asc versus NaPic/MgCit (PDR: 56[28.0%] versus 32[16.6%], p=0.007; ADR: 42[21.0%] versus 23[11.9%], p=0.015), as was detection of flat lesions (43[21.5%] versus 25[13.0%], p=0.025). Cleansing quality was better with PEG+Asc than NaPic/MgCit (98.5% versus 57.5% considered successful cleansing). Overall, there were 132 treatment-emergent adverse events (93 versus 39 for PEG+Asc and NaPic/MgCit, respectively). These were mainly mild abdominal symptoms, all of which were reported for higher proportions of patients in the PEG+Asc than NaPic/MgCit group. Twice as many patients in the NaPic/MgCit versus the PEG+Asc group reported tolerance of cleansing solution as ‘very good’. Conclusions Compared with NaPic/MgCit, PEG+Asc may be more efficacious for overall cleansing ability, and subsequent detection of right-sided and flat lesions. This is likely attributable to the different administration schedules of the two bowel cleansing preparations, which may positively impact the detection and prevention of colorectal cancer, thereby improving mortality rates. Trial Registration ClinicalTrials.gov NCT01689792. PMID:25950434

NASA Numerical and Experimental Evaluation of UTRC Low Emissions Injector

NASA Technical Reports Server (NTRS)

Hicks, Yolanda R.; Tedder, Sarah A.; Anderson, Robert C.; Iannetti, Anthony C.; Smith, Lance L.; Dai, Zhongtao

2014-01-01

Computational and experimental analyses of a PICS-Pilot-In-Can-Swirler technology injector, developed by United Technologies Research Center (UTRC) are presented. NASA has defined technology targets for near term (called "N+1", circa 2015), midterm ("N+2", circa 2020) and far term ("N+3", circa 2030) that specify realistic emissions and fuel efficiency goals for commercial aircraft. This injector has potential for application in an engine to meet the Pratt & Whitney N+3 supersonic cycle goals, or the subsonic N+2 engine cycle goals. Experimental methods were employed to investigate supersonic cruise points as well as select points of the subsonic cycle engine; cruise, approach, and idle with a slightly elevated inlet pressure. Experiments at NASA employed gas analysis and a suite of laser-based measurement techniques to characterize the combustor flow downstream from the PICS dump plane. Optical diagnostics employed for this work included Planar Laser-Induced Fluorescence of fuel for injector spray pattern and Spontaneous Raman Spectroscopy for relative species concentration of fuel and CO2. The work reported here used unheated (liquid) Jet-A fuel for all fuel circuits and cycle conditions. The initial tests performed by UTRC used vaporized Jet-A to simulate the expected supersonic cruise condition, which anticipated using fuel as a heat sink. Using the National Combustion Code a PICS-based combustor was modeled with liquid fuel at the supersonic cruise condition. All CFD models used a cubic non-linear k-epsilon turbulence wall functions model, and a semi-detailed Jet-A kinetic mechanism based on a surrogate fuel mixture. Two initial spray droplet size distribution and spray cone conditions were used: 1) an initial condition (Lefebvre) with an assumed Rosin-Rammler distribution, and 7 degree Solid Spray Cone; and 2) the Boundary Layer Stripping (BLS) primary atomization model giving the spray size distribution and directional properties. Contour and line plots are shown in comparison with experimental data (where this data is available) for flow velocities, fuel, and temperature distribution. The CFD results are consistent with experimental observations for fuel distribution and vaporization. Analysis of gas sample results, using a previously-developed NASA NOx correlation, indicates that for sea-level takeoff, the PICS configuration is predicted to deliver an EINOx value of about 3 for the targeted supersonic aircraft. Emissions results at supersonic cruise conditions show potential for meeting the NASA goals with liquid fuel.

NASA Numerical and Experimental Evaluation of UTRC Low Emissions Injector

NASA Technical Reports Server (NTRS)

Hicks, Yolanda R.; Tedder, Sarah A.; Anderson, Robert C.; Iannetti, Anthony C.; Smith, Lance L.; Dai, Zhongtao

2014-01-01

Computational and experimental analyses of a PICS-Pilot-In-Can-Swirler technology injector, developed by United Technologies Research Center (UTRC) are presented. NASA has defined technology targets for near term (called "N+1", circa 2015), midterm ("N+2", circa 2020) and far term ("N+3", circa 2030) that specify realistic emissions and fuel efficiency goals for commercial aircraft. This injector has potential for application in an engine to meet the Pratt & Whitney N+3 supersonic cycle goals, or the subsonic N+2 engine cycle goals. Experimental methods were employed to investigate supersonic cruise points as well as select points of the subsonic cycle engine; cruise, approach, and idle with a slightly elevated inlet pressure. Experiments at NASA employed gas analysis and a suite of laser-based measurement techniques to characterize the combustor flow downstream from the PICS dump plane. Optical diagnostics employed for this work included Planar Laser-Induced Fluorescence of fuel for injector spray pattern and Spontaneous Raman Spectroscopy for relative species concentration of fuel and CO2. The work reported here used unheated (liquid) Jet-A fuel for all fuel circuits and cycle conditions. The initial tests performed by UTRC used vaporized Jet-A to simulate the expected supersonic cruise condition, which anticipated using fuel as a heat sink. Using the National Combustion Code a PICS-based combustor was modeled with liquid fuel at the supersonic cruise condition. All CFD models used a cubic non-linear k-epsilon turbulence wall functions model, and a semi-detailed Jet-A kinetic mechanism based on a surrogate fuel mixture. Two initial spray droplet size distribution and spray cone conditions were used: (1) an initial condition (Lefebvre) with an assumed Rosin-Rammler distribution, and 7 degree Solid Spray Cone; and (2) the Boundary Layer Stripping (BLS) primary atomization model giving the spray size distribution and directional properties. Contour and line plots are shown in comparison with experimental data (where this data is available) for flow velocities, fuel, and temperature distribution. The CFD results are consistent with experimental observations for fuel distribution and vaporization. Analysis of gas sample results, using a previously-developed NASA NOx correlation, indicates that for sea-level takeoff, the PICS configuration is predicted to deliver an EINOx value of about three for the targeted supersonic aircraft. Emissions results at supersonic cruise conditions show potential for meeting the NASA goals with liquid fuel.

Biodistribution of charged F(ab')2 photoimmunoconjugates in a xenograft model of ovarian cancer.

PubMed

Duska, L R; Hamblin, M R; Bamberg, M P; Hasan, T

1997-01-01

The effect of charge modification of photoimmunoconjugates (PICs) on their biodistribution in a xenograft model of ovarian cancer was investigated. Chlorin(e6)c(e6) was attached site specifically to the F(ab')2 fragment of the murine monoclonal antibody OC125, directed against human ovarian cancer cells, via poly-1-lysine linkers carrying cationic or anionic charges. Preservation of immunoreactivity was checked by enzyme-linked immunosorbent assay (ELISA). PICs were radiolabelled with 125I and compared with non-specific rabbit IgG PICs after intraperitoneal (i.p.) injection into nude mice. Samples were taken from normal organs and tumour at 3 h and 24 h. Tumour to normal 125I ratios showed that the cationic OC125F(ab')2 PIC had the highest tumour selectivity. Ratios for c(e6) were uniformly higher than for 125I, indicating that c(e6) became separated from 125I. OC125F(ab')2 gave highest tissue values of 125I, followed by cationic OC125F(ab')2 PIC; other species were much lower. The amounts of c(e6) delivered per gram of tumour were much higher for cationic OC125F(ab')2 PIC than for other species. The results indicate that cationic charge stimulates the endocytosis and lysosomal degradation of the OC125F(ab')2-pl-c(e6) that has bound to the i.p. tumour. Positively charged PICs may have applications in the i.p. photoimmunotherapy of minimal residual ovarian cancer.

Insulin receptors and downstream substrates associate with membrane microdomains after treatment with insulin or chromium(III) picolinate.

PubMed

Al-Qatati, Abeer; Winter, Peter W; Wolf-Ringwall, Amber L; Chatterjee, Pabitra B; Van Orden, Alan K; Crans, Debbie C; Roess, Deborah A; Barisas, B George

2012-04-01

We have examined the association of insulin receptors (IR) and downstream signaling molecules with membrane microdomains in rat basophilic leukemia (RBL-2H3) cells following treatment with insulin or tris(2-pyridinecarbxylato)chromium(III) (Cr(pic)(3)). Single-particle tracking demonstrated that individual IR on these cells exhibited reduced lateral diffusion and increased confinement within 100 nm-scale membrane compartments after treatment with either 200 nM insulin or 10 μM Cr(pic)(3). These treatments also increased the association of native IR, phosphorylated insulin receptor substrate 1 and phosphorylated AKT with detergent-resistant membrane microdomains of characteristically high buoyancy. Confocal fluorescence microscopic imaging of Di-4-ANEPPDHQ labeled RBL-2H3 cells also showed that plasma membrane lipid order decreased following treatment with Cr(pic)(3) but was not altered by insulin treatment. Fluorescence correlation spectroscopy demonstrated that Cr(pic)(3) did not affect IR cell-surface density or compete with insulin for available binding sites. Finally, Fourier transform infrared spectroscopy indicated that Cr(pic)(3) likely associates with the lipid interface in reverse-micelle model membranes. Taken together, these results suggest that activation of IR signaling in a cellular model system by both insulin and Cr(pic)(3) involves retention of IR in specialized nanometer-scale membrane microdomains but that the insulin-like effects of Cr(pic)(3) are due to changes in membrane lipid order rather than to direct interactions with IR. © Springer Science+Business Media, LLC 2011

Chromium picolinate inhibits resistin secretion in insulin-resistant 3T3-L1 adipocytes via activation of amp-activated protein kinase.

PubMed

Wang, Yi-Qun; Dong, Yi; Yao, Ming-Hui

2009-08-01

1. Chromium picolinate (CrPic) has been recommended as an alternative therapeutic regimen for Type 2 diabetes mellitus (T2DM). However, the molecular mechanism underlying the action of CrPic is poorly understood. 2. Using normal and insulin-resistant 3T3-L1 adipocytes, we examined the effects of CrPic on the gene transcription and secretion of adiponectin and resistin. In addition, using immunoblotting, ELISA and real-time reverse transcription-polymerase chain reaction (RT-PCR), we investigated the effects of 10 nmol/L CrPic for 24 h on AMP-activated protein kinase (AMPK) to determine whether this pathway contributed to the regulation of adiponectin and resistin expression and secretion. 3. Chromium picolinate did not modulate the expression of adiponectin and resistin; however, it did significantly inhibit the secretion of resistin, but not adiponectin, by normal and insulin-resistant 3T3-L1 adipocytes in vitro. Furthermore, although CrPic markedly elevated levels of phosphorylated AMPK and acetyl CoA carboxylase in 3T3-L1 adipocytes, it had no effect on the levels of AMPK alpha-1 and alpha-2 mRNA transcripts. Importantly, inhibition of AMPK by 2 h pretreatment of cells with 20 micromol/L compound C completely abolished the CrPic-induced suppression of resistin secretion. 4. In conclusion, the data suggest that CrPic inhibits resistin secretion via activation of AMPK in normal and insulin-resistant 3T3-L1 adipocytes.

Skeletal muscle-derived interstitial progenitor cells (PICs) display stem cell properties, being clonogenic, self-renewing, and multi-potent in vitro and in vivo.

PubMed

Cottle, Beverley J; Lewis, Fiona C; Shone, Victoria; Ellison-Hughes, Georgina M

2017-07-04

The development of cellular therapies to treat muscle wastage with disease or age is paramount. Resident muscle satellite cells are not currently regarded as a viable cell source due to their limited migration and growth capability ex vivo. This study investigated the potential of muscle-derived PW1 + /Pax7 - interstitial progenitor cells (PICs) as a source of tissue-specific stem/progenitor cells with stem cell properties and multipotency. Sca-1 + /PW1 + PICs were identified on tissue sections from hind limb muscle of 21-day-old mice, isolated by magnetic-activated cell sorting (MACS) technology and their phenotype and characteristics assessed over time in culture. Green fluorescent protein (GFP)-labelled PICs were used to determine multipotency in vivo in a tumour formation assay. Isolated PICs expressed markers of pluripotency (Oct3/4, Sox2, and Nanog), were clonogenic, and self-renewing with >60 population doublings, and a population doubling time of 15.8 ± 2.9 h. PICs demonstrated an ability to generate both striated and smooth muscle, whilst also displaying the potential to differentiate into cell types of the three germ layers both in vitro and in vivo. Moreover, PICs did not form tumours in vivo. These findings open new avenues for a variety of solid tissue engineering and regeneration approaches, utilising a single multipotent stem cell type isolated from an easily accessible source such as skeletal muscle.

Measurement of In Vitro Integration Activity of HIV-1 Preintegration Complexes.

PubMed

Balasubramaniam, Muthukumar; Davids, Benem; Addai, Amma B; Pandhare, Jui; Dash, Chandravanu

2017-02-22

HIV-1 envelope proteins engage cognate receptors on the target cell surface, which leads to viral-cell membrane fusion followed by the release of the viral capsid (CA) core into the cytoplasm. Subsequently, the viral Reverse Transcriptase (RT), as part of a namesake nucleoprotein complex termed the Reverse Transcription Complex (RTC), converts the viral single-stranded RNA genome into a double-stranded DNA copy (vDNA). This leads to the biogenesis of another nucleoprotein complex, termed the pre-integration complex (PIC), composed of the vDNA and associated virus proteins and host factors. The PIC-associated viral integrase (IN) orchestrates the integration of the vDNA into the host chromosomal DNA in a temporally and spatially regulated two-step process. First, the IN processes the 3' ends of the vDNA in the cytoplasm and, second, after the PIC traffics to the nucleus, it mediates integration of the processed vDNA into the chromosomal DNA. The PICs isolated from target cells acutely infected with HIV-1 are functional in vitro, as they are competent to integrate the associated vDNA into an exogenously added heterologous target DNA. Such PIC-based in vitro integration assays have significantly contributed to delineating the mechanistic details of retroviral integration and to discovering IN inhibitors. In this report, we elaborate upon an updated HIV-1 PIC assay that employs a nested real-time quantitative Polymerase Chain Reaction (qPCR)-based strategy for measuring the in vitro integration activity of isolated native PICs.

Asteroid Bennu Temperature Maps for OSIRIS-REx Spacecraft and Instrument Thermal Analyses

NASA Technical Reports Server (NTRS)

Choi, Michael K.; Emery, Josh; Delbo, Marco

2014-01-01

A thermophysical model has been developed to generate asteroid Bennu surface temperature maps for OSIRIS-REx spacecraft and instrument thermal design and analyses at the Critical Design Review (CDR). Two-dimensional temperature maps for worst hot and worst cold cases are used in Thermal Desktop to assure adequate thermal design margins. To minimize the complexity of the Bennu geometry in Thermal Desktop, it is modeled as a sphere instead of the radar shape. The post-CDR updated thermal inertia and a modified approach show that the new surface temperature predictions are more benign. Therefore the CDR Bennu surface temperature predictions are conservative.

OSIRIS-REx Rollout for Launch

NASA Image and Video Library

2016-09-07

In a view from ground level looking up, a United Launch Alliance Atlas V rocket begins to roll out of the Vertical Integration Facility to Space Launch Complex 41 at Cape Canaveral Air Force Station in Florida. The launch vehicle will boost NASA’s Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer, or OSIRIS-REx spacecraft. This will be the first U.S. mission to sample an asteroid, retrieve at least two ounces of surface material and return it to Earth for study. The asteroid, Bennu, may hold clues to the origin of the solar system and the source of water and organic molecules found on Earth.

OSIRIS and SOMBRERO Inertial Fusion Power Plant Designs, Volume 2: Designs, Assessments, and Comparisons

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meier, W. R.; Bieri, R. L.; Monsler, M. J.

1992-03-01

This is a comprehensive design study of two Inertial Fusion Energy (IFE) electric power plants. Conceptual designs are presented for a fusion reactor (called Osiris) using an induction-linac heavy-ion beam driver, and another (called SOMBRERO) using a KrF laser driver. The designs covered all aspects of IFE power plants, including the chambers, heat transport and power conversion systems, balance-of-plant facilities, target fabrication, target injection and tracking, as well as the heavy-ion and KrF drivers. The point designs were assessed and compared in terms of their environmental & safety aspects, reliability and availability, economics, and technology development needs.

OSIRIS-REx Rollout for Launch

NASA Image and Video Library

2016-09-07

A United Launch Alliance Atlas V rocket is reflected in the water as it rolls out of the Vertical Integration Facility on its way to Space Launch Complex 41 at Cape Canaveral Air Force Station in Florida. The launch vehicle will boost NASA’s Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer, or OSIRIS-REx spacecraft. This will be the first U.S. mission to sample an asteroid, retrieve at least two ounces of surface material and return it to Earth for study. The asteroid, Bennu, may hold clues to the origin of the solar system and the source of water and organic molecules found on Earth.

Strategy for Ranking the Science Value of the Surface of Asteroid 101955 Bennu for Sample Site Selection for Osiris-REx

NASA Technical Reports Server (NTRS)

Nakamura-Messenger, K.; Connolly, H. C., Jr.; Lauretta, D. S.

2014-01-01

OSRIS-REx is NASA's New Frontiers 3 sample return mission that will return at least 60 g of pristine surface material from near-Earth asteroid 101955 Bennu in September 2023. The scientific value of the sample increases enormously with the amount of knowledge captured about the geological context from which the sample is collected. The OSIRIS-REx spacecraft is highly maneuverable and capable of investigating the surface of Bennu at scales down to the sub-cm. The OSIRIS-REx instruments will characterize the overall surface geology including spectral properties, microtexture, and geochemistry of the regolith at the sampling site in exquisite detail for up to 505 days after encountering Bennu in August 2018. The mission requires at the very minimum one acceptable location on the asteroid where a touch-and-go (TAG) sample collection maneuver can be successfully per-formed. Sample site selection requires that the follow-ing maps be produced: Safety, Deliverability, Sampleability, and finally Science Value. If areas on the surface are designated as safe, navigation can fly to them, and they have ingestible regolith, then the scientific value of one site over another will guide site selection.

The big lobe of 67P/Churyumov-Gerasimenko comet: morphological and spectrophotometric evidences of layering as from OSIRIS data

NASA Astrophysics Data System (ADS)

Ferrari, Sabrina; Penasa, L.; La Forgia, F.; Massironi, M.; Naletto, G.; Lazzarin, M.; Fornasier, S.; Hasselmann, P. H.; Lucchetti, A.; Pajola, M.; Ferri, F.; Cambianica, P.; Oklay, N.; Tubiana, C.; Sierks, H.; Lamy, P. L.; Rodrigo, R.; Koschny, D.; Davidsson, B.; Barucci, M. A.; Bertaux, J.-L.; Bertini, I.; Bodewits, D.; Cremonese, G.; Da Deppo, V.; Debei, S.; De Cecco, M.; Deller, J.; Franceschi, M.; Frattin, E.; Fulle, M.; Groussin, O.; Gutiérrez, P. J.; Güttler, C.; Hviid, S. F.; Ip, W.-H.; Jorda, L.; Keller, H. U.; Knollenberg, J.; Kührt, E.; Küppers, M.; Lara, L. M.; López-Moreno, J. J.; Marzari, F.; Shi, X.; Simioni, E.; Thomas, N.; Vincent, J.-B.

2018-06-01

Between 2014 and 2016, ESA's Rosetta OSIRIS cameras acquired multiple-filters images of the layered nucleus of comet 67P/Churyumov-Gerasimenko, ranging from ultraviolet to near-infrared wavelengths. No correlation between layers disposition and surface spectral variegation has been observed so far. This paper investigates possible spectral differences among decametre-thickness outcropping layers of the biggest lobe of the comet by means of OSIRIS image dataset. A two-classes Maximum Likelihood classification was applied on consolidated outcrops and relative deposits identified on post-perihelion multispectral images of the big lobe. We distinguished multispectral data on the basis of the structural elevation of the onion-shell Ellipsoidal Model of 67P. The spatial distribution of the two classes displays a clear dependence on the structural elevation, with the innermost class resulting over 50% brighter that the outermost one. Consolidated cometary materials located at different structural levels are characterized by different brightness and revealed due to the selective removal of large volumes. This variegation can be attributed to a different texture of the outcrop surface and/or to a different content of refractory materials.

Quantifying emissions of CO and NOx using observations from MOPITT, OMI, TES, and OSIRIS

NASA Astrophysics Data System (ADS)

Zhang, X.; Jones, D. B. A.; Keller, M.; Walker, T. W.; Jiang, Z.; Henze, D. K.; Bourassa, A. E.; Degenstein, D. A.; Rochon, Y. J.

2016-12-01

We use the GEOS-Chem four-dimensional variational (4D-var) data assimilation with satellite observations of multiple chemical species to estimate emissions of CO and NOx, as well as the tropospheric concentrations of O3. In doing so, we utilize CO retrievals from The Measurements of Pollution In The Troposphere (MOPITT), O3 retrievals from the Tropospheric Emission Spectrometer (TES), O3 retrievals from the Optical Spectrograph and InfraRed Imager System (OSIRIS), and NO2 columns from the Ozone Monitoring Instrument (OMI). By integrating these data in the 4D-Var scheme, we obtain a chemical state in the model that is consistent with all of the data over the assimilation period. In this context, for example, we find that combining TES and OSIRIS improves O3, particularly in the tropical upper troposphere (by 10-20%), which leads to a reduction in the uncertainty of the NOx emission estimates. However, although assimilating multiple chemical species provides a stronger constraint on the chemical, state, there are still large uncertainties on the CO and NOx emission estimates, due to the dependence of the results on the selection of the assimilation window and how the datasets are weighted in the cost function.

A structured approach to Exposure Based Waiving of human health endpoints under REACH developed in the OSIRIS project.

PubMed

Marquart, Hans; Meijster, Tim; Van de Bovenkamp, Marja; Ter Burg, Wouter; Spaan, Suzanne; Van Engelen, Jacqueline

2012-03-01

Exposure Based Waiving (EBW) is one of the options in REACH when there is insufficient hazard data on a specific endpoint. Rules for adaptation of test requirements are specified and a general option for EBW is given via Appendix XI of REACH, allowing waiving of repeated dose toxicity studies, reproductive toxicity studies and carcinogenicity studies under a number of conditions if exposure is very low. A decision tree is described that was developed in the European project OSIRIS (Optimised Strategies for Risk Assessment of Industrial Chemicals through Integration of Non-Test and Test Information) to help decide in what cases EBW can be justified. The decision tree uses specific criteria as well as more general questions. For the latter, guidance on interpretation and resulting conclusions is provided. Criteria and guidance are partly based on an expert elicitation process. Among the specific criteria a number of proposed Thresholds of Toxicological Concern are used. The decision tree, expanded with specific parts on absorption, distribution, metabolism and excretion that are not described in this paper, is implemented in the OSIRIS webtool on integrated testing strategies. Copyright © 2011 Elsevier Inc. All rights reserved.

Cliffs versus plains: Can ROSINA/COPS and OSIRIS data of comet 67P/Churyumov-Gerasimenko in autumn 2014 constrain inhomogeneous outgassing?

NASA Astrophysics Data System (ADS)

Marschall, R.; Mottola, S.; Su, C. C.; Liao, Y.; Rubin, M.; Wu, J. S.; Thomas, N.; Altwegg, K.; Sierks, H.; Ip, W.-H.; Keller, H. U.; Knollenberg, J.; Kührt, E.; Lai, I. L.; Skorov, Y.; Jorda, L.; Preusker, F.; Scholten, F.; Vincent, J.-B.; Osiris Team; Rosina Team

2017-09-01

Context. This paper describes the modelling of gas and dust data acquired in the period August to October 2014 from the European Space Agency's Rosetta spacecraft when it was in close proximity to the nucleus of comet 67P/Churyumov-Gerasimenko. Aims: With our 3D gas and dust comae models this work attempts to test the hypothesis that cliff activity on comet 67P/Churyumov-Gerasimenko can solely account for the local gas density data observed by the Rosetta Orbiter Spectrometer for Ion and Neutral Analysis (ROSINA) and the dust brightnesses seen by the Optical, Spectroscopic, and Infrared Remote Imaging System (OSIRIS) in the considered time span. Methods: The model uses a previously developed shape model of the nucleus. From this, the water sublimation rates and gas temperatures at the surface are computed. The gas expansion is modelled with a 3D Direct Simulation Monte Carlo algorithm. A dust drag algorithm is then used to compute dust volume number densities in the coma, which are then converted to brightnesses using Mie theory and a line-of-sight integration. Furthermore we have studied the impact of topographic re-radiation on the models. Results: We show that gas activity from only cliff areas produces a fit to the ROSINA/COPS data that is as statistically good as a purely insolation-driven model. In contrast, pure cliff activity does not reproduce the dust brightness observed by OSIRIS and can thus be ruled out. On the other hand, gas activity from the Hapi region in addition to cliff activity produces a statistically better fit to the ROSINA/COPS data than purely insolation-driven outgassing and also fits the OSIRIS observations rather well. We found that topographic re-radiation does not contribute significantly to the sublimation behaviour of H2O but plays an important role in how the gas flux interacts with the irregular shape of the nucleus. Conclusions: We demonstrate that fits to the observations are non-unique. We can conclude however that gas and dust activity from cliffs and the Hapi region are consistent with the ROSINA/COPS and OSIRIS data sets for the considered time span and are thus a plausible solution. Models with activity from low gravitational slopes alone provide a statistically inferior solution.

Vocal individuality cues in the African penguin (Spheniscus demersus): a source-filter theory approach.

PubMed

Favaro, Livio; Gamba, Marco; Alfieri, Chiara; Pessani, Daniela; McElligott, Alan G

2015-11-25

The African penguin is a nesting seabird endemic to southern Africa. In penguins of the genus Spheniscus vocalisations are important for social recognition. However, it is not clear which acoustic features of calls can encode individual identity information. We recorded contact calls and ecstatic display songs of 12 adult birds from a captive colony. For each vocalisation, we measured 31 spectral and temporal acoustic parameters related to both source and filter components of calls. For each parameter, we calculated the Potential of Individual Coding (PIC). The acoustic parameters showing PIC ≥ 1.1 were used to perform a stepwise cross-validated discriminant function analysis (DFA). The DFA correctly classified 66.1% of the contact calls and 62.5% of display songs to the correct individual. The DFA also resulted in the further selection of 10 acoustic features for contact calls and 9 for display songs that were important for vocal individuality. Our results suggest that studying the anatomical constraints that influence nesting penguin vocalisations from a source-filter perspective, can lead to a much better understanding of the acoustic cues of individuality contained in their calls. This approach could be further extended to study and understand vocal communication in other bird species.

Vocal individuality cues in the African penguin (Spheniscus demersus): a source-filter theory approach

PubMed Central

Favaro, Livio; Gamba, Marco; Alfieri, Chiara; Pessani, Daniela; McElligott, Alan G.

2015-01-01

The African penguin is a nesting seabird endemic to southern Africa. In penguins of the genus Spheniscus vocalisations are important for social recognition. However, it is not clear which acoustic features of calls can encode individual identity information. We recorded contact calls and ecstatic display songs of 12 adult birds from a captive colony. For each vocalisation, we measured 31 spectral and temporal acoustic parameters related to both source and filter components of calls. For each parameter, we calculated the Potential of Individual Coding (PIC). The acoustic parameters showing PIC ≥ 1.1 were used to perform a stepwise cross-validated discriminant function analysis (DFA). The DFA correctly classified 66.1% of the contact calls and 62.5% of display songs to the correct individual. The DFA also resulted in the further selection of 10 acoustic features for contact calls and 9 for display songs that were important for vocal individuality. Our results suggest that studying the anatomical constraints that influence nesting penguin vocalisations from a source-filter perspective, can lead to a much better understanding of the acoustic cues of individuality contained in their calls. This approach could be further extended to study and understand vocal communication in other bird species. PMID:26602001

Dissipation and particle energization in moderate to low beta turbulent plasma via PIC simulations

DOE PAGES

Makwana, Kirit; Li, Hui; Guo, Fan; ...

2017-05-30

Here, we simulate decaying turbulence in electron-positron pair plasmas using a fully-kinetic particle-in-cell (PIC) code. We run two simulations with moderate-to-low plasma β (the ratio of thermal pressure to magnetic pressure). The energy decay rate is found to be similar in both cases. The perpendicular wave-number spectrum of magnetic energy shows a slope betweenmore » $${k}_{\\perp }^{-1.3}$$ and $${k}_{\\perp }^{-1.1}$$, where the perpendicular (⊥) and parallel (∥) directions are defined with respect to the magnetic field. The particle kinetic energy distribution function shows the formation of a non-thermal feature in the case of lower plasma β, with a slope close to E-1. The correlation between thin turbulent current sheets and Ohmic heating by the dot product of electric field (E) and current density (J) is investigated. By heating the parallel E∥ centerdot J∥ term dominates the perpendicular E⊥ centerdot J⊥ term. Regions of strong E∥ centerdot J∥ are spatially well-correlated with regions of intense current sheets, which also appear correlated with regions of strong E∥ in the low β simulation, suggesting an important role of magnetic reconnection in the dissipation of low β plasma turbulence.« less

A numerical analysis of plasma non-uniformity in the parallel plate VHF-CCP and the comparison among various model

NASA Astrophysics Data System (ADS)

Sawada, Ikuo

2012-10-01

We measured the radial distribution of electron density in a 200 mm parallel plate CCP and compared it with results from numerical simulations. The experiments were conducted with pure Ar gas with pressures ranging from 15 to 100 mTorr and 60 MHz applied at the top electrode with powers from 500 to 2000W. The measured electron profile is peaked in the center, and the relative non-uniformity is higher at 100 mTorr than at 15 mTorr. We compare the experimental results with simulations with both HPEM and Monte-Carlo/PIC codes. In HPEM simulations, we used either fluid or electron Monte-Carlo module, and the Poisson or the Electromagnetic solver. None of the models were able to duplicate the experimental results quantitatively. However, HPEM with the electron Monte-Carlo module and PIC qualitatively matched the experimental results. We will discuss the results from these models and how they illuminate the mechanism of enhanced electron central peak.[4pt] [1] T. Oshita, M. Matsukuma, S.Y. Kang, I. Sawada: The effect of non-uniform RF voltage in a CCP discharge, The 57^th JSAP Spring Meeting 2010[4pt] [2] I. Sawada, K. Matsuzaki, S.Y. Kang, T. Ohshita, M. Kawakami, S. Segawa: 1-st IC-PLANTS, 2008

Dissipation and particle energization in moderate to low beta turbulent plasma via PIC simulations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Makwana, Kirit; Li, Hui; Guo, Fan

Here, we simulate decaying turbulence in electron-positron pair plasmas using a fully-kinetic particle-in-cell (PIC) code. We run two simulations with moderate-to-low plasma β (the ratio of thermal pressure to magnetic pressure). The energy decay rate is found to be similar in both cases. The perpendicular wave-number spectrum of magnetic energy shows a slope betweenmore » $${k}_{\\perp }^{-1.3}$$ and $${k}_{\\perp }^{-1.1}$$, where the perpendicular (⊥) and parallel (∥) directions are defined with respect to the magnetic field. The particle kinetic energy distribution function shows the formation of a non-thermal feature in the case of lower plasma β, with a slope close to E-1. The correlation between thin turbulent current sheets and Ohmic heating by the dot product of electric field (E) and current density (J) is investigated. By heating the parallel E∥ centerdot J∥ term dominates the perpendicular E⊥ centerdot J⊥ term. Regions of strong E∥ centerdot J∥ are spatially well-correlated with regions of intense current sheets, which also appear correlated with regions of strong E∥ in the low β simulation, suggesting an important role of magnetic reconnection in the dissipation of low β plasma turbulence.« less

Evaluating CoLiDeS + Pic: The Role of Relevance of Pictures in User Navigation Behaviour

ERIC Educational Resources Information Center

Karanam, Saraschandra; van Oostendorp, Herre; Indurkhya, Bipin

2012-01-01

CoLiDeS + Pic is a cognitive model of web-navigation that incorporates semantic information from pictures into CoLiDeS. In our earlier research, we have demonstrated that by incorporating semantic information from pictures, CoLiDeS + Pic can predict the hyperlinks on the shortest path more frequently, and also with greater information scent,…

Chromium nanoparticle exhibits higher absorption efficiency than chromium picolinate and chromium chloride in Caco-2 cell monolayers.

PubMed

Zha, L-Y; Xu, Z-R; Wang, M-Q; Gu, L-Y

2008-04-01

This study was conducted to determine whether chromium nanoparticle (CrNano) exhibited higher absorption efficiency and possessed unique absorption mechanism in comparison to chromium picolinate (CrPic) and chromium chloride (CrCl(3)), as was postulated by previous reports. Twenty-one-day-old Caco-2 cell monolayers grown on semipermeable membranes in Snapwell tissue culture bichambers were incubated with CrNano, CrPic or CrCl(3) to examine their transport and uptake respectively. In the concentration range of 0.2-20 micromol/l, transport of CrNano, CrPic and CrCl(3) across Caco-2 monolayers both in apical-to-basolateral and basolateral-to-apical direction was concentration-, and time-dependent, and temperature independent. The apparent permeability coefficient (P(app)) of CrNano was between 5.89 and 7.92 x 10(-6) cm/s and that of CrPic and CrCl(3) was between 3.52 and 5.31 x 10(-6) cm/s and between 0.97 and 1.37 x 10(-6) cm/s respectively. Uptake of CrNano, CrPic and CrCl(3) by both apical and basolateral membranes was concentration- and time-dependent. Uptake of CrNano by apical membrane was significantly (p < 0.05) decreased when the incubation temperature was reduced from 37 degrees C to 4 degrees C. The transport efficiency of CrNano, CrPic and CrCl(3) after incubation for 120 min at 37 degrees C was 15.83% +/- 0.76%, 9.08% +/- 0.25% and 2.11% +/- 0.53% respectively. The uptake efficiency of CrNano, CrPic and CrCl(3) was 10.08% +/- 0.76%, 4.73% +/- 0.60% and 0.88% +/- 0.08% respectively. It was concluded that the epithelial transport of CrNano, CrPic and CrCl(3) across the Caco-2 cell monolayers was mainly via passive transport pathways. In addition, CrNano exhibited considerably higher absorption efficiency than both CrPic and CrCl(3) in Caco-2 cell monolayers.

Temperature affects the morphology and calcification of Emiliania huxleyi strains

NASA Astrophysics Data System (ADS)

Rosas-Navarro, Anaid; Langer, Gerald; Ziveri, Patrizia

2016-05-01

The global warming debate has sparked an unprecedented interest in temperature effects on coccolithophores. The calcification response to temperature changes reported in the literature, however, is ambiguous. The two main sources of this ambiguity are putatively differences in experimental setup and strain specificity. In this study we therefore compare three strains isolated in the North Pacific under identical experimental conditions. Three strains of Emiliania huxleyi type A were grown under non-limiting nutrient and light conditions, at 10, 15, 20 and 25 °C. All three strains displayed similar growth rate versus temperature relationships, with an optimum at 20-25 °C. Elemental production (particulate inorganic carbon (PIC), particulate organic carbon (POC), total particulate nitrogen (TPN)), coccolith mass, coccolith size, and width of the tube element cycle were positively correlated with temperature over the sub-optimum to optimum temperature range. The correlation between PIC production and coccolith mass/size supports the notion that coccolith mass can be used as a proxy for PIC production in sediment samples. Increasing PIC production was significantly positively correlated with the percentage of incomplete coccoliths in one strain only. Generally, coccoliths were heavier when PIC production was higher. This shows that incompleteness of coccoliths is not due to time shortage at high PIC production. Sub-optimal growth temperatures lead to an increase in the percentage of malformed coccoliths in a strain-specific fashion. Since in total only six strains have been tested thus far, it is presently difficult to say whether sub-optimal temperature is an important factor causing malformations in the field. The most important parameter in biogeochemical terms, the PIC : POC ratio, shows a minimum at optimum growth temperature in all investigated strains. This clarifies the ambiguous picture featuring in the literature, i.e. discrepancies between PIC : POC-temperature relationships reported in different studies using different strains and different experimental setups. In summary, global warming might cause a decline in coccolithophore's PIC contribution to the rain ratio, as well as improved fitness in some genotypes due to fewer coccolith malformations.

Alternative modeling methods for plasma-based Rf ion sources

DOE Office of Scientific and Technical Information (OSTI.GOV)

Veitzer, Seth A., E-mail: veitzer@txcorp.com; Kundrapu, Madhusudhan, E-mail: madhusnk@txcorp.com; Stoltz, Peter H., E-mail: phstoltz@txcorp.com

Rf-driven ion sources for accelerators and many industrial applications benefit from detailed numerical modeling and simulation of plasma characteristics. For instance, modeling of the Spallation Neutron Source (SNS) internal antenna H{sup −} source has indicated that a large plasma velocity is induced near bends in the antenna where structural failures are often observed. This could lead to improved designs and ion source performance based on simulation and modeling. However, there are significant separations of time and spatial scales inherent to Rf-driven plasma ion sources, which makes it difficult to model ion sources with explicit, kinetic Particle-In-Cell (PIC) simulation codes. Inmore » particular, if both electron and ion motions are to be explicitly modeled, then the simulation time step must be very small, and total simulation times must be large enough to capture the evolution of the plasma ions, as well as extending over many Rf periods. Additional physics processes such as plasma chemistry and surface effects such as secondary electron emission increase the computational requirements in such a way that even fully parallel explicit PIC models cannot be used. One alternative method is to develop fluid-based codes coupled with electromagnetics in order to model ion sources. Time-domain fluid models can simulate plasma evolution, plasma chemistry, and surface physics models with reasonable computational resources by not explicitly resolving electron motions, which thereby leads to an increase in the time step. This is achieved by solving fluid motions coupled with electromagnetics using reduced-physics models, such as single-temperature magnetohydrodynamics (MHD), extended, gas dynamic, and Hall MHD, and two-fluid MHD models. We show recent results on modeling the internal antenna H{sup −} ion source for the SNS at Oak Ridge National Laboratory using the fluid plasma modeling code USim. We compare demonstrate plasma temperature equilibration in two-temperature MHD models for the SNS source and present simulation results demonstrating plasma evolution over many Rf periods for different plasma temperatures. We perform the calculations in parallel, on unstructured meshes, using finite-volume solvers in order to obtain results in reasonable time.« less

Alternative modeling methods for plasma-based Rf ion sources.

PubMed

Veitzer, Seth A; Kundrapu, Madhusudhan; Stoltz, Peter H; Beckwith, Kristian R C

2016-02-01

Rf-driven ion sources for accelerators and many industrial applications benefit from detailed numerical modeling and simulation of plasma characteristics. For instance, modeling of the Spallation Neutron Source (SNS) internal antenna H(-) source has indicated that a large plasma velocity is induced near bends in the antenna where structural failures are often observed. This could lead to improved designs and ion source performance based on simulation and modeling. However, there are significant separations of time and spatial scales inherent to Rf-driven plasma ion sources, which makes it difficult to model ion sources with explicit, kinetic Particle-In-Cell (PIC) simulation codes. In particular, if both electron and ion motions are to be explicitly modeled, then the simulation time step must be very small, and total simulation times must be large enough to capture the evolution of the plasma ions, as well as extending over many Rf periods. Additional physics processes such as plasma chemistry and surface effects such as secondary electron emission increase the computational requirements in such a way that even fully parallel explicit PIC models cannot be used. One alternative method is to develop fluid-based codes coupled with electromagnetics in order to model ion sources. Time-domain fluid models can simulate plasma evolution, plasma chemistry, and surface physics models with reasonable computational resources by not explicitly resolving electron motions, which thereby leads to an increase in the time step. This is achieved by solving fluid motions coupled with electromagnetics using reduced-physics models, such as single-temperature magnetohydrodynamics (MHD), extended, gas dynamic, and Hall MHD, and two-fluid MHD models. We show recent results on modeling the internal antenna H(-) ion source for the SNS at Oak Ridge National Laboratory using the fluid plasma modeling code USim. We compare demonstrate plasma temperature equilibration in two-temperature MHD models for the SNS source and present simulation results demonstrating plasma evolution over many Rf periods for different plasma temperatures. We perform the calculations in parallel, on unstructured meshes, using finite-volume solvers in order to obtain results in reasonable time.

An Efficient Randomized Algorithm for Real-Time Process Scheduling in PicOS Operating System

NASA Astrophysics Data System (ADS)

Helmy*, Tarek; Fatai, Anifowose; Sallam, El-Sayed

PicOS is an event-driven operating environment designed for use with embedded networked sensors. More specifically, it is designed to support the concurrency in intensive operations required by networked sensors with minimal hardware requirements. Existing process scheduling algorithms of PicOS; a commercial tiny, low-footprint, real-time operating system; have their associated drawbacks. An efficient, alternative algorithm, based on a randomized selection policy, has been proposed, demonstrated, confirmed for efficiency and fairness, on the average, and has been recommended for implementation in PicOS. Simulations were carried out and performance measures such as Average Waiting Time (AWT) and Average Turn-around Time (ATT) were used to assess the efficiency of the proposed randomized version over the existing ones. The results prove that Randomized algorithm is the best and most attractive for implementation in PicOS, since it is most fair and has the least AWT and ATT on average over the other non-preemptive scheduling algorithms implemented in this paper.

Metabolic stability of new anticonvulsants in body fluids and organ homogenates.

PubMed

Marszałek, Dorota; Goldnik, Anna; Pluciński, Franciszek; Mazurek, Aleksander P; Jakubiak, Anna; Lis, Ewa; Tazbir, Piotr; Koziorowska, Agnieszka

2012-01-01

The stability as a function of time of compounds with established anticonvulsant activity: picolinic acid benzylamide (Pic-BZA), picolinic acid 2-fluorobenzylamide (Pic-2-F-BZA), picolinic acid 3-fluorobenzylamide (Pic-3-F-BZA), picolinic acid 4-fluorobenzylamide (Pic-4-F-BZA) and picolinic acid 2-methylbenzylamide (Pic-2-Me-BZA) in body fluids and homogenates of body organs were determined after incubation. It was found that they decompose relatively rapidly in liver and kidney and are stable against enzymes present in body fluids and some organs. These results are consistent with the bond strength expressed as total energy of amide bonds (calculated by quantum chemical methods) in the studied anticonvulsants. The calculated values of the amide bond energy are: 199.4 kcal/mol, 200.2 kcal/mol, 207.5 kcal/mol, 208.4 kcal/mol and 198.2 kcal/mol, respectively. The strength of the amide bonds in the studied anticonvulsants correctly reflects their stability in liver or kidney.

Functional interplay between Mediator and TFIIB in preinitiation complex assembly in relation to promoter architecture.

PubMed

Eychenne, Thomas; Novikova, Elizaveta; Barrault, Marie-Bénédicte; Alibert, Olivier; Boschiero, Claire; Peixeiro, Nuno; Cornu, David; Redeker, Virginie; Kuras, Laurent; Nicolas, Pierre; Werner, Michel; Soutourina, Julie

2016-09-15

Mediator is a large coregulator complex conserved from yeast to humans and involved in many human diseases, including cancers. Together with general transcription factors, it stimulates preinitiation complex (PIC) formation and activates RNA polymerase II (Pol II) transcription. In this study, we analyzed how Mediator acts in PIC assembly using in vivo, in vitro, and in silico approaches. We revealed an essential function of the Mediator middle module exerted through its Med10 subunit, implicating a key interaction between Mediator and TFIIB. We showed that this Mediator-TFIIB link has a global role on PIC assembly genome-wide. Moreover, the amplitude of Mediator's effect on PIC formation is gene-dependent and is related to the promoter architecture in terms of TATA elements, nucleosome occupancy, and dynamics. This study thus provides mechanistic insights into the coordinated function of Mediator and TFIIB in PIC assembly in different chromatin contexts. © 2016 Eychenne et al.; Published by Cold Spring Harbor Laboratory Press.

DoD Personnel Security Program

DTIC Science & Technology

1987-01-01

Baltimore, Maryland 21203 Message Address: DIS PIC BALTIMORE MD/ /D0640 The request will include subject’s name, grade, social security number, date and...requests for initial investigations will be submitted to PIC regardless of their urgency. If, however, there is an urgent need for a postadjudication...investigation, or the mailing of a request to PIC for initia- tion of a postadjudication case would prejudice timely pursuit of investigative action, the

iVPIC: A low-­dispersion, energy-­conserving relativistic PIC solver for LPI simulations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chacon, Luis

We have developed a novel low-­dispersion, exactly energy-­conserving PIC algorithm for the relativistic Vlasov-­Maxwell system. The approach features an exact energy conservation theorem while preserving the favorable performance and numerical dispersion properties of explicit PIC. The new algorithm has the potential to enable much longer laser-­plasma-­interaction (LPI) simulations than are currently possible.

Measurement of greenhouse gas emissions from agricultural sites using open-path optical remote sensing method.

PubMed

Ro, Kyoung S; Johnson, Melvin H; Varma, Ravi M; Hashmonay, Ram A; Hunt, Patrick

2009-08-01

Improved characterization of distributed emission sources of greenhouse gases such as methane from concentrated animal feeding operations require more accurate methods. One promising method is recently used by the USEPA. It employs a vertical radial plume mapping (VRPM) algorithm using optical remote sensing techniques. We evaluated this method to estimate emission rates from simulated distributed methane sources. A scanning open-path tunable diode laser was used to collect path-integrated concentrations (PICs) along different optical paths on a vertical plane downwind of controlled methane releases. Each cycle consists of 3 ground-level PICs and 2 above ground PICs. Three- to 10-cycle moving averages were used to reconstruct mass equivalent concentration plum maps on the vertical plane. The VRPM algorithm estimated emission rates of methane along with meteorological and PIC data collected concomitantly under different atmospheric stability conditions. The derived emission rates compared well with actual released rates irrespective of atmospheric stability conditions. The maximum error was 22 percent when 3-cycle moving average PICs were used; however, it decreased to 11% when 10-cycle moving average PICs were used. Our validation results suggest that this new VRPM method may be used for improved estimations of greenhouse gas emission from a variety of agricultural sources.

Simultaneous analysis of Cr(III), Cr(VI), and chromium picolinate in foods using capillary electrophoresis-inductively coupled plasma mass spectrometry.

PubMed

Chen, YiQuan; Chen, JinFa; Xi, Zhiming; Yang, Guidi; Wu, Zujian; Li, JianRong; Fu, FengFu

2015-05-01

We herein reported a method for the simultaneous detection of trace Cr(VI), Cr(III), and chromium(III) picolinate (CrPic) in foods using CE-ICP-MS together with ultrasonic-assisted extraction. The Cr(III) (Cr(3+) ) was chelated with trans-1,2-diaminocyclohexane-N,N,N´,N´-tetraacetic acid (DCTA) to form a single charged Cr-DCTA(-) complex. Then, Cr(VI) (CrO4 (2-) ), Cr-DCTA(-) , and CrPic were separated by CE within 8 min under a separation voltage of -13 KV followed by their monitoring with ICP mass spectrometer (ICP-MS). The proposed method is simple, effective, and sensitive. It has an instrument detection limit of 0.10, 0.18, and 0.20 ngCr/mL for Cr(VI), Cr(III), and CrPic, respectively. With the help of the methods, we have successfully determined Cr(VI), Cr(III), and CrPic in nutritional supplement (CrPic yeast tablet) with an RSD (n = 5) <6% and a recovery of 93-103%. The experimental results showed that CrPic was the main speciation of chromium in the nutritional supplement, with a concentration of 1514.6 μg Cr/g. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

PIC1, an Ancient Permease in Arabidopsis Chloroplasts, Mediates Iron Transport[W

PubMed Central

Duy, Daniela; Wanner, Gerhard; Meda, Anderson R.; von Wirén, Nicolaus; Soll, Jürgen; Philippar, Katrin

2007-01-01

In chloroplasts, the transition metals iron and copper play an essential role in photosynthetic electron transport and act as cofactors for superoxide dismutases. Iron is essential for chlorophyll biosynthesis, and ferritin clusters in plastids store iron during germination, development, and iron stress. Thus, plastidic homeostasis of transition metals, in particular of iron, is crucial for chloroplast as well as plant development. However, very little is known about iron uptake by chloroplasts. Arabidopsis thaliana PERMEASE IN CHLOROPLASTS1 (PIC1), identified in a screen for metal transporters in plastids, contains four predicted α-helices, is targeted to the inner envelope, and displays homology with cyanobacterial permease-like proteins. Knockout mutants of PIC1 grew only heterotrophically and were characterized by a chlorotic and dwarfish phenotype reminiscent of iron-deficient plants. Ultrastructural analysis of plastids revealed severely impaired chloroplast development and a striking increase in ferritin clusters. Besides upregulation of ferritin, pic1 mutants showed differential regulation of genes and proteins related to iron stress or transport, photosynthesis, and Fe-S cluster biogenesis. Furthermore, PIC1 and its cyanobacterial homolog mediated iron accumulation in an iron uptake–defective yeast mutant. These observations suggest that PIC1 functions in iron transport across the inner envelope of chloroplasts and hence in cellular metal homeostasis. PMID:17337631

Independent contrasts and PGLS regression estimators are equivalent.

PubMed

Blomberg, Simon P; Lefevre, James G; Wells, Jessie A; Waterhouse, Mary

2012-05-01

We prove that the slope parameter of the ordinary least squares regression of phylogenetically independent contrasts (PICs) conducted through the origin is identical to the slope parameter of the method of generalized least squares (GLSs) regression under a Brownian motion model of evolution. This equivalence has several implications: 1. Understanding the structure of the linear model for GLS regression provides insight into when and why phylogeny is important in comparative studies. 2. The limitations of the PIC regression analysis are the same as the limitations of the GLS model. In particular, phylogenetic covariance applies only to the response variable in the regression and the explanatory variable should be regarded as fixed. Calculation of PICs for explanatory variables should be treated as a mathematical idiosyncrasy of the PIC regression algorithm. 3. Since the GLS estimator is the best linear unbiased estimator (BLUE), the slope parameter estimated using PICs is also BLUE. 4. If the slope is estimated using different branch lengths for the explanatory and response variables in the PIC algorithm, the estimator is no longer the BLUE, so this is not recommended. Finally, we discuss whether or not and how to accommodate phylogenetic covariance in regression analyses, particularly in relation to the problem of phylogenetic uncertainty. This discussion is from both frequentist and Bayesian perspectives.

Biodistribution of charged F(ab')2 photoimmunoconjugates in a xenograft model of ovarian cancer.

PubMed Central

Duska, L. R.; Hamblin, M. R.; Bamberg, M. P.; Hasan, T.

1997-01-01

The effect of charge modification of photoimmunoconjugates (PICs) on their biodistribution in a xenograft model of ovarian cancer was investigated. Chlorin(e6)c(e6) was attached site specifically to the F(ab')2 fragment of the murine monoclonal antibody OC125, directed against human ovarian cancer cells, via poly-1-lysine linkers carrying cationic or anionic charges. Preservation of immunoreactivity was checked by enzyme-linked immunosorbent assay (ELISA). PICs were radiolabelled with 125I and compared with non-specific rabbit IgG PICs after intraperitoneal (i.p.) injection into nude mice. Samples were taken from normal organs and tumour at 3 h and 24 h. Tumour to normal 125I ratios showed that the cationic OC125F(ab')2 PIC had the highest tumour selectivity. Ratios for c(e6) were uniformly higher than for 125I, indicating that c(e6) became separated from 125I. OC125F(ab')2 gave highest tissue values of 125I, followed by cationic OC125F(ab')2 PIC; other species were much lower. The amounts of c(e6) delivered per gram of tumour were much higher for cationic OC125F(ab')2 PIC than for other species. The results indicate that cationic charge stimulates the endocytosis and lysosomal degradation of the OC125F(ab')2-pl-c(e6) that has bound to the i.p. tumour. Positively charged PICs may have applications in the i.p. photoimmunotherapy of minimal residual ovarian cancer. PMID:9062404

Exposure of pregnant mice to chromium picolinate results in skeletal defects in their offspring.

PubMed

Bailey, M M; Boohaker, J G; Sawyer, R D; Behling, J E; Rasco, J F; Jernigan, J J; Hood, R D; Vincent, J B

2006-06-01

Chromium(III) picolinate, [Cr(pic)(3)], is a widely marketed dietary supplement. However, Cr(pic)(3) has been associated with oxidative damage to DNA in rats and mutations and DNA fragmentation in cell cultures. In isolated case reports, Cr(pic)(3) supplementation has been said to cause adverse effects, such as anemia, renal failure, liver dysfunction, and neuronal impairment. To date, no studies have been published regarding the safety of chromium picolinate supplementation to a developing fetus, although Cr(pic)(3) has been recommended for pregnant women who are diagnosed with gestational diabetes. From gestation days (GD) 6-17, pregnant CD-1 mice were fed diets containing either 200 mg/kg Cr(pic)(3), 200 mg/kg CrCl(3), 174 mg/kg picolinic acid, or the diet only to determine if Cr(pic)(3), CrCl(3), or picolinic acid could cause developmental toxicity. Dams were sacrificed on GD 17, and their litters were examined for adverse effects. The incidence of bifurcated cervical arches was significantly increased in fetuses from the Cr(pic)(3) group as compared to the diet-only group. Fetuses in the picolinic acid-treated group had an incidence double that of the control group; however, this increase was not statistically significant. Fetuses in the CrCl(3) group did not differ from the controls in any variable examined. No maternal toxicity was observed in any of the treatment groups. High maternal oral exposures to chromium picolinate can cause morphological defects in developing offspring of mice.

Effect of dental cements on peri-implant microbial community: comparison of the microbial communities inhabiting the peri-implant tissue when using different luting cements.

PubMed

Korsch, Michael; Marten, Silke-Mareike; Dötsch, Andreas; Jáuregui, Ruy; Pieper, Dietmar H; Obst, Ursula

2016-12-01

Cementing dental restorations on implants poses the risk of undetected excess cement. Such cement remnants may favor the development of inflammation in the peri-implant tissue. The effect of excess cement on the bacterial community is not yet known. The aim of this study was to analyze the effect of two different dental cements on the composition of the microbial peri-implant community. In a cohort of 38 patients, samples of the peri-implant tissue were taken with paper points from one implant per patient. In 15 patients, the suprastructure had been cemented with a zinc oxide-eugenol cement (Temp Bond, TB) and in 23 patients with a methacrylate cement (Premier Implant Cement, PIC). The excess cement found as well as suppuration was documented. Subgingival samples of all patients were analyzed for taxonomic composition by means of 16S amplicon sequencing. None of the TB-cemented implants had excess cement or suppuration. In 14 (61%) of the PIC, excess cement was found. Suppuration was detected in 33% of the PIC implants without excess cement and in 100% of the PIC implants with excess cement. The taxonomic analysis of the microbial samples revealed an accumulation of oral pathogens in the PIC patients independent of the presence of excess cement. Significantly fewer oral pathogens occurred in patients with TB compared to patients with PIC. Compared with TB, PIC favors the development of suppuration and the growth of periodontal pathogens. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Absolute radiometric calibration of Landsat using a pseudo invariant calibration site

USGS Publications Warehouse

Helder, D.; Thome, K.J.; Mishra, N.; Chander, G.; Xiong, Xiaoxiong; Angal, A.; Choi, Tae-young

2013-01-01

Pseudo invariant calibration sites (PICS) have been used for on-orbit radiometric trending of optical satellite systems for more than 15 years. This approach to vicarious calibration has demonstrated a high degree of reliability and repeatability at the level of 1-3% depending on the site, spectral channel, and imaging geometries. A variety of sensors have used this approach for trending because it is broadly applicable and easy to implement. Models to describe the surface reflectance properties, as well as the intervening atmosphere have also been developed to improve the precision of the method. However, one limiting factor of using PICS is that an absolute calibration capability has not yet been fully developed. Because of this, PICS are primarily limited to providing only long term trending information for individual sensors or cross-calibration opportunities between two sensors. This paper builds an argument that PICS can be used more extensively for absolute calibration. To illustrate this, a simple empirical model is developed for the well-known Libya 4 PICS based on observations by Terra MODIS and EO-1 Hyperion. The model is validated by comparing model predicted top-of-atmosphere reflectance values to actual measurements made by the Landsat ETM+ sensor reflective bands. Following this, an outline is presented to develop a more comprehensive and accurate PICS absolute calibration model that can be Système international d'unités (SI) traceable. These initial concepts suggest that absolute calibration using PICS is possible on a broad scale and can lead to improved on-orbit calibration capabilities for optical satellite sensors.

Double-Stranded RNA-Dependent Protein Kinase Regulates the Motility of Breast Cancer Cells

PubMed Central

Xu, Mei; Chen, Gang; Wang, Siying; Liao, Mingjun; Frank, Jacqueline A.; Bower, Kimberly A.; Zhang, Zhuo; Shi, Xianglin; Luo, Jia

2012-01-01

Double-stranded RNA (dsRNA)-dependent protein kinase (PKR) is an interferon-induced protein kinase that plays a central role in the anti-viral process. Due to its pro-apoptotic and anti-proliferative action, there is an increased interest in PKR modulation as an anti-tumor strategy. PKR is overexpressed in breast cancer cells; however, the role of PKR in breast cancer cells is unclear. The expression/activity of PKR appears inversely related to the aggressiveness of breast cancer cells. The current study investigated the role of PKR in the motility/migration of breast cancer cells. The activation of PKR by a synthesized dsRNA (PIC) significantly decreased the motility of several breast cancer cell lines (BT474, MDA-MB231 and SKBR3). PIC inhibited cell migration and blocked cell membrane ruffling without affecting cell viability. PIC also induced the reorganization of the actin cytoskeleton and impaired the formation of lamellipodia. These effects of PIC were reversed by the pretreatment of a selective PKR inhibitor. PIC also activated p38 mitogen-activated protein kinase (MAPK) and its downstream MAPK-activated protein kinase 2 (MK2). PIC-induced activation of p38 MAPK and MK2 was attenuated by the PKR inhibitor and the PKR siRNA, but a selective p38 MAPK inhibitor (SB203580) or other MAPK inhibitors did not affect PKR activity, indicating that PKR is upstream of p38 MAPK/MK2. Cofilin is an actin severing protein and regulates membrane ruffling, lamellipodia formation and cell migration. PIC inhibited cofilin activity by enhancing its phosphorylation at Ser3. PIC activated LIM kinase 1 (LIMK1), an upstream kinase of cofilin in a p38 MAPK-dependent manner. We concluded that the activation of PKR suppressed cell motility by regulating the p38 MAPK/MK2/LIMK/cofilin pathway. PMID:23112838

Identification of amino acid residues of mammalian mitochondrial phosphate carrier important for its functional expression in yeast cells, as achieved by PCR-mediated random mutation and gap-repair cloning.

PubMed

Yamagoshi, Ryohei; Yamamoto, Takenori; Hashimoto, Mitsuru; Sugahara, Ryohei; Shiotsuki, Takahiro; Miyoshi, Hideto; Terada, Hiroshi; Shinohara, Yasuo

2017-01-01

The mitochondrial phosphate carrier (PiC) of mammals, but not the yeast one, is synthesized with a presequence. The deletion of this presequence of the mammalian PiC was reported to facilitate the import of the carrier into yeast mitochondria, but the question as to whether or not mammalian PiC could be functionally expressed in yeast mitochondria was not addressed. In the present study, we first examined whether the defective growth on a glycerol plate of yeast cells lacking the yeast PiC gene could be reversed by the introduction of expression vectors of rat PiCs. The introduction of expression vectors encoding full-length rat PiC (rPiC) or rPiC lacking the presequence (ΔNrPiC) was ineffective in restoring growth on the glycerol plates. When we examined the expression levels of individual rPiCs in yeast mitochondria, ΔNrPiC was expressed at a level similar to that of yeast PiC, but that of rPiC was very low. These results indicated that ΔNrPiC expressed in yeast mitochondria is inert. Next, we sought to isolate "revertants" viable on the glycerol plate by expressing randomly mutated ΔNrPiC, and obtained two clones. These clones carried either of two mutations, F267S or F282S; and these mutations restored the transport function of ΔNrPiC in yeast mitochondria. These two Phe residues were conserved in human carrier (hPiC), and the transport function of ΔNhPiC expressed in yeast mitochondria was also markedly improved by their substitutions. Thus, substitution of F267S or F282S was concluded to be important for functional expression of mammalian PiCs in yeast mitochondria. Copyright © 2016 Elsevier B.V. and Mitochondria Research Society. All rights reserved.