The relevance of external quality assessment for molecular testing for ALK positive non-small cell lung cancer: results from two pilot rounds show room for optimization.

PubMed

Tembuyser, Lien; Tack, Véronique; Zwaenepoel, Karen; Pauwels, Patrick; Miller, Keith; Bubendorf, Lukas; Kerr, Keith; Schuuring, Ed; Thunnissen, Erik; Dequeker, Elisabeth M C

2014-01-01

Molecular profiling should be performed on all advanced non-small cell lung cancer with non-squamous histology to allow treatment selection. Currently, this should include EGFR mutation testing and testing for ALK rearrangements. ROS1 is another emerging target. ALK rearrangement status is a critical biomarker to predict response to tyrosine kinase inhibitors such as crizotinib. To promote high quality testing in non-small cell lung cancer, the European Society of Pathology has introduced an external quality assessment scheme. This article summarizes the results of the first two pilot rounds organized in 2012-2013. Tissue microarray slides consisting of cell-lines and resection specimens were distributed with the request for routine ALK testing using IHC or FISH. Participation in ALK FISH testing included the interpretation of four digital FISH images. Data from 173 different laboratories was obtained. Results demonstrate decreased error rates in the second round for both ALK FISH and ALK IHC, although the error rates were still high and the need for external quality assessment in laboratories performing ALK testing is evident. Error rates obtained by FISH were lower than by IHC. The lowest error rates were observed for the interpretation of digital FISH images. There was a large variety in FISH enumeration practices. Based on the results from this study, recommendations for the methodology, analysis, interpretation and result reporting were issued. External quality assessment is a crucial element to improve the quality of molecular testing.

Discovery of novel cell wall-active compounds using P ywaC, a sensitive reporter of cell wall stress, in the model gram-positive bacterium Bacillus subtilis.

PubMed

Czarny, T L; Perri, A L; French, S; Brown, E D

2014-06-01

The emergence of antibiotic resistance in recent years has radically reduced the clinical efficacy of many antibacterial treatments and now poses a significant threat to public health. One of the earliest studied well-validated targets for antimicrobial discovery is the bacterial cell wall. The essential nature of this pathway, its conservation among bacterial pathogens, and its absence in human biology have made cell wall synthesis an attractive pathway for new antibiotic drug discovery. Herein, we describe a highly sensitive screening methodology for identifying chemical agents that perturb cell wall synthesis, using the model of the Gram-positive bacterium Bacillus subtilis. We report on a cell-based pilot screen of 26,000 small molecules to look for cell wall-active chemicals in real time using an autonomous luminescence gene cluster driven by the promoter of ywaC, which encodes a guanosine tetra(penta)phosphate synthetase that is expressed under cell wall stress. The promoter-reporter system was generally much more sensitive than growth inhibition testing and responded almost exclusively to cell wall-active antibiotics. Follow-up testing of the compounds from the pilot screen with secondary assays to verify the mechanism of action led to the discovery of 9 novel cell wall-active compounds. Copyright © 2014, American Society for Microbiology. All Rights Reserved.

Large area, low cost space solar cells with optional wraparound contacts

NASA Technical Reports Server (NTRS)

Michaels, D.; Mendoza, N.; Williams, R.

1981-01-01

Design parameters for two large area, low cost solar cells are presented, and electron irradiation testing, thermal alpha testing, and cell processing are discussed. The devices are a 2 ohm-cm base resistivity silicon cell with an evaporated aluminum reflector produced in a dielectric wraparound cell, and a 10 ohm-cm silicon cell with the BSF/BSR combination and a conventional contact system. Both cells are 5.9 x 5.9 cm and require 200 micron thick silicon material due to mission weight constraints. Normalized values for open circuit voltage, short circuit current, and maximum power calculations derived from electron radiation testing are given. In addition, thermal alpha testing values of absorptivity and emittance are included. A pilot cell processing run produced cells averaging 14.4% efficiencies at AMO 28 C. Manufacturing for such cells will be on a mechanized process line, and the area of coverslide application technology must be considered in order to achieve cost effective production.

Reconstructing Cell Lineages from Single-Cell Gene Expression Data: A Pilot Study

DTIC Science & Technology

2016-08-30

Reconstructing cell lineages from single- cell gene expression data: a pilot study The goal of this pilot study is to develop novel mathematical...methods, by leveraging tools developed in the bifurcation theory, to infer the underlying cell -state dynamics from single- cell gene expression data. Our...proposed method contains two steps. The first step is to reconstruct the temporal order of the cells from gene expression data, whereas the second

Establishing a cost-per-result of laboratory-based, reflex Cryptococcal antigenaemia screening (CrAg) in HIV+ patients with CD4 counts less than 100 cells/μl using a Lateral Flow Assay (LFA) at a typical busy CD4 laboratory in South Africa.

PubMed

Cassim, Naseem; Schnippel, Kathryn; Coetzee, Lindi Marie; Glencross, Deborah Kim

2017-01-01

Cryptococcal meningitis is a major cause of mortality and morbidity in countries with high HIV prevalence, primarily affecting patients whose CD4 are < = 100 cells/μl. Routine Cryptococcal Antigen (CrAg) screening is thus recommended in the South African HIV treatment guidelines for all patients with CD4 counts < = 100 cells/μl, followed by pre-emptive anti-fungal therapy where CrAg results are positive. A laboratory-based reflexed CrAg screening approach, using a Lateral Flow Assay (LFA) on remnant EDTA CD4 blood samples, was piloted at three CD4 laboratories. This study aimed to assess the cost-per-result of laboratory-based reflexed CrAg screening at one pilot CD4 referral laboratory. CD4 test volumes from 2014 were extracted to estimate percentage of CD4 < = 100 cells/μl. Daily average volumes were derived, assuming 12 months per/year and 21.73 working days per/month. Costing analyses were undertaken using Microsoft Excel and Stata with a provider prospective. The cost-per-result was estimated using a bottom-up method, inclusive of test kits and consumables (reagents), laboratory equipment and technical effort costs. The ZAR/$ exchange of 14.696/$1 was used, where applicable. One-way sensitivity analyses on the cost-per-result were conducted for possible error rates (3%- 8%, reductions or increases in reagent costs as well as test volumes (ranging from -60% to +60%). The pilot CD4 laboratory performed 267000 CD4 tests in 2014; ~ 9.3% (27500) reported CD4< = 100 cells/μl, equivalent to 106 CrAg tests performed daily. A batch of 30-tests could be performed in 1.6 hours, including preparation and analysis time. A cost-per-result of $4.28 was reported, with reagents contributing $3.11 (72.8%), while technical effort and laboratory equipment overheads contributed $1.17 (27.2%) and $0.03 (<1%) respectively. One-way sensitivity analyses including increasing or decreasing test volumes by 60% revealed a cost-per-result range of $3.84 to $6.03. A cost-per-result of $4.28 was established in a typical CD4 service laboratory to enable local budgetary cost projections and programmatic cost-effectiveness modelling. Varying reagent costs linked to currency exchange and varying test volumes in different levels of service can lead to varying cost-per-test and technical effort to manage workload, with an inverse relationship of higher costs expected at lower volumes of tests.

Newborn screening for severe T and B cell immunodeficiency in Israel: a pilot study.

PubMed

Somech, Raz; Lev, Atar; Simon, Amos J; Korn, David; Garty, Ben Zion; Amariglio, Ninette; Rechavi, Gideon; Almashanu, Shlomo; Zlotogora, Joel; Etzioni, Amos

2013-08-01

Enumeration of T cell receptor excision circles (TREC) was recently adopted as a neonatal screening assay for severe combined immunodeficiency (SCID). Enumeration of kappa-deleting recombination excision circle (KREC) copy numbers can be similarly used for early assessment of B cell lymphopenia. To assess the ability of TREC and KREC counts to identify patients with combined T and B cell immunodeficiency in a pilot study in Israel. We studied seven children born in Israel during the years 2010-2011 and later diagnosed with SCID, and an additional patient with pure B cell immunodeficiency. TREC and KREC in peripheral blood upon diagnosis and in their neonatal Guthrie cards were analyzed using real-time quantitative polymerase chain reaction, as were Guthrie cards with dried blood spots from healthy newborns and from normal and SCID-like controls. The first features suggestive of SCID presented at age 3.1 +/- 2.4 months in all patients. Yet, the diagnosis was made 4.1 +/- 2.9 months later. Their TREC were undetectable or significantly low at their clinical diagnosis and in their originally stored Guthrie cards, irrespective of the amount of their circulating T cells. KREC were undetectable in six SCID patients who displayed B cell lymphopenia in addition to T cell lymphopenia. KREC were also undetectable in one patient with pure B cell immunodeficiency. TREC and KREC quantification are useful screening tests for severe T and B cell immunodeficiency. Implementation of these tests is highly important especially in countries such as Israel where a high frequency of consanguinity is known to exist.

77 FR 18793 - Spectrum Sharing Innovation Test-Bed Pilot Program

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-28

.... 120322212-2212-01] Spectrum Sharing Innovation Test-Bed Pilot Program AGENCY: National Telecommunications... Innovation Test-Bed pilot program to assess whether devices employing Dynamic Spectrum Access techniques can... Spectrum Sharing Innovation Test-Bed (Test-Bed) pilot program to examine the feasibility of increased...

14 CFR 61.307 - What tests do I have to take to obtain a sport pilot certificate?

Code of Federal Regulations, 2014 CFR

2014-01-01

... sport pilot certificate? 61.307 Section 61.307 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... INSTRUCTORS Sport Pilots § 61.307 What tests do I have to take to obtain a sport pilot certificate? To obtain a sport pilot certificate, you must pass the following tests: (a) Knowledge test. You must pass a...

14 CFR 61.307 - What tests do I have to take to obtain a sport pilot certificate?

Code of Federal Regulations, 2012 CFR

2012-01-01

... sport pilot certificate? 61.307 Section 61.307 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... INSTRUCTORS Sport Pilots § 61.307 What tests do I have to take to obtain a sport pilot certificate? To obtain a sport pilot certificate, you must pass the following tests: (a) Knowledge test. You must pass a...

14 CFR 61.307 - What tests do I have to take to obtain a sport pilot certificate?

Code of Federal Regulations, 2013 CFR

2013-01-01

... sport pilot certificate? 61.307 Section 61.307 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... INSTRUCTORS Sport Pilots § 61.307 What tests do I have to take to obtain a sport pilot certificate? To obtain a sport pilot certificate, you must pass the following tests: (a) Knowledge test. You must pass a...

14 CFR 91.1065 - Initial and recurrent pilot testing requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Initial and recurrent pilot testing... Ownership Operations Program Management § 91.1065 Initial and recurrent pilot testing requirements. (a) No program manager or owner may use a pilot, nor may any person serve as a pilot, unless, since the beginning...

14 CFR 91.1065 - Initial and recurrent pilot testing requirements.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Initial and recurrent pilot testing... Ownership Operations Program Management § 91.1065 Initial and recurrent pilot testing requirements. (a) No program manager or owner may use a pilot, nor may any person serve as a pilot, unless, since the beginning...

Steps to Enhance Early Recovery After Hematopoietic Stem Cell Transplantation: Lessons Learned From a Physical Activity Feasibility Study.

PubMed

Hacker, Eileen Danaher; Peters, Tara; Patel, Pritesh; Rondelli, Damiano

This pilot study tested and refined a free-living physical activity intervention. The investigators evaluated the acceptability and feasibility of the intervention after hematopoietic stem cell transplantation and determined preliminary effects on physical activity, fatigue, muscle strength, functional ability, and quality of life. This pilot study used a 1-group, pretest-posttest design. The free-living physical activity intervention consisted of an education component and 6 weeks of gradually increasing physical activity after discharge from the hospital. The intervention was designed to increase steps by 10% weekly. Subjects were assessed before transplantation and during the seventh week after discharge from the hospital after completing the intervention. Pretest-posttest scores were analyzed with paired t tests. Subject wore the physical activity tracker for an average of 38 of 42 days and met their physical activity goals 57% of the time. Subjects reported significantly less physical fatigue after the free-living physical activity intervention compared with baseline (P = .05). Improvements in quality of life approached significance (P = .06). The findings demonstrate that the free-living physical activity intervention implemented during the very early recovery period after transplantation is feasible and acceptable. The intervention potentially reduces fatigue and improves quality of life. The positive results must be interpreted cautiously given the pilot nature of the study. The evidence supports continued investigation.

Commercial Pilot Knowledge Test Guide

DOT National Transportation Integrated Search

1995-01-01

The FAA has available hundreds of computer testing centers nationwide. These testing centers offer the full range of airman knowledge tests including military competence, instrument foreign pilot, and pilot examiner predesignated tests. Refer to appe...

Effects of fish oils on ex vivo B-cell responses of obese subjects upon BCR/TLR stimulation: a pilot study.

PubMed

Guesdon, William; Kosaraju, Rasagna; Brophy, Patricia; Clark, Angela; Dillingham, Steve; Aziz, Shahnaz; Moyer, Fiona; Willson, Kate; Dick, James R; Patil, Shivajirao Prakash; Balestrieri, Nicholas; Armstrong, Michael; Reisdroph, Nichole; Shaikh, Saame Raza

2018-03-01

The long-chain n-3 polyunsaturated fatty acids (LC-PUFAs) eicosapentaenoic (EPA) and docosahexaenoic acid (DHA) in fish oil have immunomodulatory properties. B cells are a poorly studied target of EPA/DHA in humans. Therefore, in this pilot study, we tested how n-3 LC-PUFAs influence B-cell responses of obese humans. Obese men and women were assigned to consume four 1-g capsules per day of olive oil (OO, n=12), fish oil (FO, n=12) concentrate or high-DHA-FO concentrate (n=10) for 12 weeks in a parallel design. Relative to baseline, FO (n=9) lowered the percentage of circulating memory and plasma B cells, whereas the other supplements had no effect. There were no postintervention differences between the three supplements. Next, ex vivo B-cell cytokines were assayed after stimulation of Toll-like receptors (TLRs) and/or the B-cell receptor (BCR) to determine if the effects of n-3 LC-PUFAs were pathway-dependent. B-cell IL-10 and TNFα secretion was respectively increased with high DHA-FO (n=10), relative to baseline, with respective TLR9 and TLR9+BCR stimulation. OO (n=12) and FO (n=12) had no influence on B-cell cytokines compared to baseline, and there were no differences in postintervention cytokine levels between treatment groups. Finally, ex vivo antibody levels were assayed with FO (n=7) after TLR9+BCR stimulation. Compared to baseline, FO lowered IgM but not IgG levels accompanied by select modifications to the plasma lipidome. Altogether, the results suggest that n-3 LC-PUFAs could modulate B-cell activity in humans, which will require further testing in a larger cohort. Copyright © 2017 Elsevier Inc. All rights reserved.

14 CFR 21.37 - Flight test pilot.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Flight test pilot. 21.37 Section 21.37... PROCEDURES FOR PRODUCTS AND PARTS Type Certificates § 21.37 Flight test pilot. Each applicant for a normal... holding an appropriate pilot certificate to make the flight tests required by this part. [Doc. No. 5085...

14 CFR 21.37 - Flight test pilot.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Flight test pilot. 21.37 Section 21.37... PROCEDURES FOR PRODUCTS AND PARTS Type Certificates § 21.37 Flight test pilot. Each applicant for a normal... holding an appropriate pilot certificate to make the flight tests required by this part. [Doc. No. 5085...

14 CFR 21.37 - Flight test pilot.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Flight test pilot. 21.37 Section 21.37... PROCEDURES FOR PRODUCTS AND PARTS Type Certificates § 21.37 Flight test pilot. Each applicant for a normal... holding an appropriate pilot certificate to make the flight tests required by this part. [Doc. No. 5085...

Shortcuts for Pilot Testing Instructional Materials.

ERIC Educational Resources Information Center

Howe, R. John; Pearlstein, Gloria

1995-01-01

A mini-pilot test was conducted by the Department of Labor's Employment Standards Administration to develop training on enforcing the Federal Family and Medical Leave Act. The situation that necessitated the test is presented; mini-pilot test examples are explained; and pros and cons of the mini-pilots are examined. A sidebar contains suggestions…

A Pilot Study of the Performance Characteristics of the D-dimer in Presumed Sepsis

DTIC Science & Technology

2010-05-01

20 breaths/min or PaCO2 ថ mm Hg White Blood Cell Count >12,000 cells /mm3, ɜ,000 cells /mm3, or >10% bands Table 2. Sepsis Definitions Sepsis 2 or...Jersey), a quantitative, microlatex agglutination test with a reference cut-off of 0.4 mg/dL as positive. The assay is run on venous blood collected...sensitivity of only ~61- 67% for patients who ultimately were found to have positive blood cultures.12 This study used a semi-quantitative D-dimer

Photochemical bonding of epithelial cell-seeded collagen lattice to rat muscle layer for esophageal tissue engineering: a pilot study

NASA Astrophysics Data System (ADS)

Chan, Barbara P.; Sato, M.; Vacanti, Joseph P.; Kochevar, Irene E.; Redmond, Robert W.

2005-04-01

Bilayered tube structures consist of epithelial cell-seeded collagen lattice and muscle layer have been fabricated for esophageal tissue engineering. Good adhesion between layers in order to facilitate cell infiltration and neovascularization in the collagen lattice is required. Previous efforts include using other bioglues such as fibrin glue and silicone tube as the physical support. However, the former is subjected to chances of transmitting blood-born infectious disease and is time consuming while the latter requires a second surgical procedure. The current project aimed to bond the cell-seeded collagen lattice to muscle layer using photochemical bonding, which has previously been demonstrated a rapid and non-thermal procedure in bonding collagenous tissues. Rat esophageal epithelial cells were seeded on collagen lattice and together with the latissimus dorsi muscle layer, were exposed to a photosensitizer rose Bengal at the bonding surface. An argon laser was used to irradiate the approximated layers. Bonding strength was measured during the peeling test of the collagen layer from the muscle layer. Post-bonding cell viability was assessed using a modified NADH-diaphorase microassay. A pilot in vivo study was conducted by directly bonding the cell-seeded collagen layer onto the muscle flap in rats and the structures were characterized histologically. Photochemical bonding was found to significantly increase the adherence at the bonding interface without compromising the cell viability. This indicates the feasibility of using the technique to fabricate multi-layered structures in the presence of living cells. The pilot animal study demonstrated integration of the collagen lattice with the muscle layer at the bonding interface although the subsequent surgical manipulation disturbed the integration at some region. This means that an additional procedure removing the tube could be avoided if the approximation and thus the bonding are optimized. Cell infiltration and neovascularization were also evident demonstrating that direct bonding of engineered tissue structures in particular those with low processability such as collagen lattice to the host tissue is feasible.

Increased circulating stem cells and better cognitive performance in traumatic brain injury subjects following hyperbaric oxygen therapy.

PubMed

Shandley, Sabrina; Wolf, E George; Schubert-Kappan, Christine M; Baugh, Laura M; Richards, Michael F; Prye, Jennifer; Arizpe, Helen M; Kalns, John

2017-01-01

Traumatic brain injury (TBI) may cause persistent cognitive dysfunction. A pilot clinical study was performed to determine if hyperbaric oxygen (HBO₂) treatment improves cognitive performance. It was hypothesized that stem cells, mobilized by HBO₂ treatment, are recruited to repair damaged neuronal tissue. This hypothesis was tested by measuring the relative abundance of stem cells in peripheral blood and cognitive performance during this clinical trial. The subject population consisted of 28 subjects with persistent cognitive impairment caused by mild to moderate TBI suffered during military deployment to Iraq or Afghanistan. Fluorescence-activated cell sorting (FACS) analysis was performed for stem cell markers in peripheral blood and correlated with variables resulting from standard tests of cognitive performance and post-traumatic stress disorder: ImPACT, BrainCheckers and PCL-M test results. HBO₂ treatment correlated with stem cell mobilization as well as increased cognitive performance. Together these results support the hypothesis that stem cell mobilization may be required for cognitive improvement in this population. Copyright© Undersea and Hyperbaric Medical Society.

Global positioning system supported pilot's display

NASA Technical Reports Server (NTRS)

Scott, Marshall M., Jr.; Erdogan, Temel; Schwalb, Andrew P.; Curley, Charles H.

1991-01-01

The hardware, software, and operation of the Microwave Scanning Beam Landing System (MSBLS) Flight Inspection System Pilot's Display is discussed. The Pilot's Display is used in conjunction with flight inspection tests that certify the Microwave Scanning Beam Landing System used at Space Shuttle landing facilities throughout the world. The Pilot's Display was developed for the pilot of test aircraft to set up and fly a given test flight path determined by the flight inspection test engineers. This display also aids the aircraft pilot when hazy or cloud cover conditions exist that limit the pilot's visibility of the Shuttle runway during the flight inspection. The aircraft position is calculated using the Global Positioning System and displayed in the cockpit on a graphical display.

The effects of pilot stress factors on handling quality assessments during US/German helicopter agility flight tests

NASA Technical Reports Server (NTRS)

Pausder, H. J.; Gerdes, R. M.

1982-01-01

Flight tests were conducted with two helicopters to study and evaluate the effects of helicopter characteristics and pilot and task demands on performance in nap-of-the-Earth flight. Different, low-level slalom courses were set up and were flown by three pilots with different levels of flight experience. A pilot rating questionnaire was used to obtain redundant information and to gain more insight into factors that influence pilot ratings. The flight test setups and procedures are described, and the pilot ratings are summarized and interpreted in close connection with the analyzed test data. Pilot stress is discussed. The influence of demands on the pilot, of the helicopter characteristics, and of other stress factors are outlined with particular emphasis on how these factors affect handling-qualities assessment.

Flight Testing the X-36: The Test Pilots Perspective

NASA Technical Reports Server (NTRS)

Walker, Laurence A.

1997-01-01

The X-36 is a 28% scale, remotely piloted research aircraft, designed to demonstrate tailless fighter agility. Powered by a modified Williams International F-112 jet engine, the X-36 uses thrust vectoring and a fly-by-wire control system. Although too small for an onboard pilot, a full-sized remote cockpit was designed to virtually place the test pilot into the aircraft using a variety of innovative techniques. To date, 22 flights have been flown, successfully completing the second phase of testing. Handling qualities have been matching predictions; the test operation is flown similarly to that for full sized manned aircraft. All takeoffs, test maneuvers and landings are flown by the test pilot, affording a greater degree of flexibility and the ability to handle the inevitable unknowns which may occur during highly experimental test programs. The cockpit environment, cues, and display techniques used in this effort have proven to enhance the 'virtual' test pilot's awareness and have helped ensure a successful RPV test program.

CD20-specific adoptive immunotherapy for lymphoma using a chimeric antigen receptor with both CD28 and 4-1BB domains: pilot clinical trial results.

PubMed

Till, Brian G; Jensen, Michael C; Wang, Jinjuan; Qian, Xiaojun; Gopal, Ajay K; Maloney, David G; Lindgren, Catherine G; Lin, Yukang; Pagel, John M; Budde, Lihua E; Raubitschek, Andrew; Forman, Stephen J; Greenberg, Philip D; Riddell, Stanley R; Press, Oliver W

2012-04-26

Cellular immune responses have the potential to elicit dramatic and sustained clinical remissions in lymphoma patients. Recent clinical trial data demonstrate that modification of T cells with chimeric antigen receptors (CARs) is a promising strategy. T cells containing CARs with costimulatory domains exhibit improved activity against tumors. We conducted a pilot clinical trial testing a "third-generation" CD20-specific CAR with CD28 and 4-1BB costimulatory domains in patients with relapsed indolent B-cell and mantle cell lymphomas. Four patients were enrolled, and 3 received T-cell infusions after cyclophosphamide lymphodepletion. Treatment was well tolerated, although one patient developed transient infusional symptoms. Two patients without evaluable disease remained progression-free for 12 and 24 months. The third patient had an objective partial remission and relapsed at 12 months after infusions. Modified T cells were detected by quantitative PCR at tumor sites and up to 1 year in peripheral blood, albeit at low levels. No evidence of host immune responses against infused cells was detected. In conclusion, adoptive immunotherapy with CD20-specific T cells was well tolerated and was associated with antitumor activity. We will pursue alternative gene transfer technologies and culture conditions in future studies to improve CAR expression and cell production efficiency.

Performance characteristics of qualified cell lines for isolation and propagation of influenza viruses for vaccine manufacturing

PubMed Central

Donis, Ruben O.; Chen, i-Mei; Davis, C Todd; Foust, Angie; Hossain, M. Jaber; Johnson, Adam; Klimov, Alexander; Loughlin, Rosette; Xu, Xiyan; Tsai, Theodore; Blayer, Simone; Trusheim, Heidi; Colegate, Tony; Fox, John; Taylor, Beverly; Hussain, Althaf; Barr, Ian; Baas, Chantal; Louwerens, Jaap; Geuns, Ed; Lee, Min-Shi; Venhuizen, odewijk; Neumeier, Elisabeth; Ziegler, Thedi

2018-01-01

Cell culture is now available as a method for the production of influenza vaccines in addition to eggs. In accordance with currently accepted practice, viruses recommended as candidates for vaccine manufacture are isolated and propagated exclusively in hens' eggs prior to distribution to manufacturers. Candidate vaccine viruses isolated in cell culture are not available to support vaccine manufacturing in mammalian cell bioreactors so egg-derived viruses have to be used. Recently influenza A (H3N2) viruses have been difficult to isolate directly in eggs. As mitigation against this difficulty, and the possibility of no suitable egg-isolated candidate viruses being available, it is proposed to consider using mammalian cell lines for primary isolation of influenza viruses as candidates for vaccine production in egg and cell platforms. To investigate this possibility, we tested the antigenic stability of viruses isolated and propagated in cell lines qualified for influenza vaccine manufacture and subsequently investigated antigen yields of such viruses in these cell lines at pilot-scale. Twenty influenza A and B-positive, original clinical specimens were inoculated in three MDCK cell lines. The antigenicity of recovered viruses was tested by hemagglutination inhibition using ferret sera against contemporary vaccine viruses and the amino acid sequences of the hemagglutinin and neuraminidase were determined. MDCK cell lines proved to be highly sensitive for virus isolation. Compared to the virus sequenced from the original specimen, viruses passaged three times in the MDCK lines showed up to 2 amino acid changes in the hemagglutinin. Antigenic stability was also established by hemagglutination inhibition titers comparable to those of the corresponding reference virus. Viruses isolated in any of the three MDCK lines grew reasonably well but variably in three MDCK cells and in VERO cells at pilot-scale. These results indicate that influenza viruses isolated in vaccine certified cell lines may well qualify for use in vaccine production. PMID:24975811

Performance characteristics of qualified cell lines for isolation and propagation of influenza viruses for vaccine manufacturing.

PubMed

Donis, Ruben O; Davis, C Todd; Foust, Angie; Hossain, M Jaber; Johnson, Adam; Klimov, Alexander; Loughlin, Rosette; Xu, Xiyan; Tsai, Theodore; Blayer, Simone; Trusheim, Heidi; Colegate, Tony; Fox, John; Taylor, Beverly; Hussain, Althaf; Barr, Ian; Baas, Chantal; Louwerens, Jaap; Geuns, Ed; Lee, Min-Shi; Venhuizen, Odewijk; Neumeier, Elisabeth; Ziegler, Thedi

2014-11-12

Cell culture is now available as a method for the production of influenza vaccines in addition to eggs. In accordance with currently accepted practice, viruses recommended as candidates for vaccine manufacture are isolated and propagated exclusively in hens' eggs prior to distribution to manufacturers. Candidate vaccine viruses isolated in cell culture are not available to support vaccine manufacturing in mammalian cell bioreactors so egg-derived viruses have to be used. Recently influenza A (H3N2) viruses have been difficult to isolate directly in eggs. As mitigation against this difficulty, and the possibility of no suitable egg-isolated candidate viruses being available, it is proposed to consider using mammalian cell lines for primary isolation of influenza viruses as candidates for vaccine production in egg and cell platforms. To investigate this possibility, we tested the antigenic stability of viruses isolated and propagated in cell lines qualified for influenza vaccine manufacture and subsequently investigated antigen yields of such viruses in these cell lines at pilot-scale. Twenty influenza A and B-positive, original clinical specimens were inoculated in three MDCK cell lines. The antigenicity of recovered viruses was tested by hemagglutination inhibition using ferret sera against contemporary vaccine viruses and the amino acid sequences of the hemagglutinin and neuraminidase were determined. MDCK cell lines proved to be highly sensitive for virus isolation. Compared to the virus sequenced from the original specimen, viruses passaged three times in the MDCK lines showed up to 2 amino acid changes in the hemagglutinin. Antigenic stability was also established by hemagglutination inhibition titers comparable to those of the corresponding reference virus. Viruses isolated in any of the three MDCK lines grew reasonably well but variably in three MDCK cells and in VERO cells at pilot-scale. These results indicate that influenza viruses isolated in vaccine certified cell lines may well qualify for use in vaccine production. Published by Elsevier Ltd.

Laboratory Study on Macro-Features of Wave Breaking Over Bars and Artificial Reefs

DTIC Science & Technology

1990-07-01

Prototype and Model Conditions of Case CE400 ( Pilot Test ) . 72 7 List of Design Parameters for Base Tests ... ........... . 72 8 List of Design Parameters...bar configurations, and the procedure was repeated. Pilot test 112. A pilot test was performed as a trial of the methodology and vali- dation of the...criterion on bar depth given by Larson and Kraus (1989) prior to actual testing . In this pilot test , the wave conditions and equilibrium bar formed in a

A Compact Energy Harvesting System for Outdoor Wireless Sensor Nodes Based on a Low-Cost In Situ Photovoltaic Panel Characterization-Modelling Unit

PubMed Central

Antolín, Diego; Calvo, Belén; Martínez, Pedro A.

2017-01-01

This paper presents a low-cost high-efficiency solar energy harvesting system to power outdoor wireless sensor nodes. It is based on a Voltage Open Circuit (VOC) algorithm that estimates the open-circuit voltage by means of a multilayer perceptron neural network model trained using local experimental characterization data, which are acquired through a novel low cost characterization system incorporated into the deployed node. Both units—characterization and modelling—are controlled by the same low-cost microcontroller, providing a complete solution which can be understood as a virtual pilot cell, with identical characteristics to those of the specific small solar cell installed on the sensor node, that besides allows an easy adaptation to changes in the actual environmental conditions, panel aging, etc. Experimental comparison to a classical pilot panel based VOC algorithm show better efficiency under the same tested conditions. PMID:28777330

A Compact Energy Harvesting System for Outdoor Wireless Sensor Nodes Based on a Low-Cost In Situ Photovoltaic Panel Characterization-Modelling Unit.

PubMed

Antolín, Diego; Medrano, Nicolás; Calvo, Belén; Martínez, Pedro A

2017-08-04

This paper presents a low-cost high-efficiency solar energy harvesting system to power outdoor wireless sensor nodes. It is based on a Voltage Open Circuit (VOC) algorithm that estimates the open-circuit voltage by means of a multilayer perceptron neural network model trained using local experimental characterization data, which are acquired through a novel low cost characterization system incorporated into the deployed node. Both units-characterization and modelling-are controlled by the same low-cost microcontroller, providing a complete solution which can be understood as a virtual pilot cell, with identical characteristics to those of the specific small solar cell installed on the sensor node, that besides allows an easy adaptation to changes in the actual environmental conditions, panel aging, etc. Experimental comparison to a classical pilot panel based VOC algorithm show better efficiency under the same tested conditions.

Experimental Studies of the Effects of Anode Composition and Process Parameters on Anode Slime Adhesion and Cathode Copper Purity by Performing Copper Electrorefining in a Pilot-Scale Cell

NASA Astrophysics Data System (ADS)

Zeng, Weizhi; Wang, Shijie; Free, Michael L.

2016-10-01

Copper electrorefining tests were conducted in a pilot-scale cell under commercial tankhouse environment to study the effects of anode compositions, current density, cathode blank width, and flow rate on anode slime behavior and cathode copper purity. Three different types of anodes (high, mid, and low impurity levels) were used in the tests and were analyzed under SEM/EDS. The harvested copper cathodes were weighed and analyzed for impurities concentrations using DC Arc. The adhered slimes and released slimes were collected, weighed, and analyzed for compositions using ICP. It was shown that the lead-to-arsenic ratio in the anodes affects the sintering and coalescence of slime particles. High current density condition can improve anode slime adhesion and cathode purity by intensifying slime particles' coalescence and dissolving part of the particles. Wide cathode blanks can raise the anodic current densities significantly and result in massive release of large slime particle aggregates, which are not likely to contaminate the cathode copper. Low flow rate can cause anode passivation and increase local temperatures in front of the anode, which leads to very intense sintering and coalescence of slime particles. The results and analyses of the tests present potential solutions for industrial copper electrorefining process.

The effects of pilot stress factors on handling quality assessments during US/German helicopter agility flight tests

NASA Technical Reports Server (NTRS)

Pausder, H.-J.; Gerdes, R. M.

1982-01-01

Flight tests were conducted with two helicopters to study and evaluate the effects of helicopter characteristics and pilot and task demands on performance in nap-of-the-earth flight. Different, low-level slalom courses were set up and were flown by three pilots with different levels of flight experience. A pilot rating questionnaire was used to obtain redundant information and to gain more insight into factors that influence pilot ratings. The flight test setups and procedures are described, and the pilot ratings are summarized and interpreted in close connection with the analyzed test data. Pilot stress is discussed. The influence of demands on the pilot, of the helicopter characteristics, and of other stress factors are outlined with particular emphasis on how these factors affect handling-qualities assessment. Previously announced in STAR as N83-13114

Private and Commercial Pilot: Free Balloon: Flight Test Guide (Part 61 Revised).

ERIC Educational Resources Information Center

Federal Aviation Administration (DOT), Washington, DC. Flight Standards Service.

The flight test guide has been prepared to assist the applicant and his instructor in preparing for the private pilot or commercial pilot certificate with a lighter-than-air category and free balloon class rating. It contains information and guidance concerning the pilot operations, procedures, and maneuvers relevant to the flight test: layout and…

Approaches to highly parameterized inversion: Pilot-point theory, guidelines, and research directions

USGS Publications Warehouse

Doherty, John E.; Fienen, Michael N.; Hunt, Randall J.

2011-01-01

Pilot points have been used in geophysics and hydrogeology for at least 30 years as a means to bridge the gap between estimating a parameter value in every cell of a model and subdividing models into a small number of homogeneous zones. Pilot points serve as surrogate parameters at which values are estimated in the inverse-modeling process, and their values are interpolated onto the modeling domain in such a way that heterogeneity can be represented at a much lower computational cost than trying to estimate parameters in every cell of a model. Although the use of pilot points is increasingly common, there are few works documenting the mathematical implications of their use and even fewer sources of guidelines for their implementation in hydrogeologic modeling studies. This report describes the mathematics of pilot-point use, provides guidelines for their use in the parameter-estimation software suite (PEST), and outlines several research directions. Two key attributes for pilot-point definitions are highlighted. First, the difference between the information contained in the every-cell parameter field and the surrogate parameter field created using pilot points should be in the realm of parameters which are not informed by the observed data (the null space). Second, the interpolation scheme for projecting pilot-point values onto model cells ideally should be orthogonal. These attributes are informed by the mathematics and have important ramifications for both the guidelines and suggestions for future research.

Commercial Pilot Practical Test Standards for Rotorcraft, Helicopter, Gyroplane

DOT National Transportation Integrated Search

1996-04-01

The Commercial Pilot Rotorcraft (Helicopter and Gyroplane) Practical Test : Standards (PTS) book has been published by the Federal Aviation : Administration (FAA) to establish the standards for commercial pilot certification : practical tests for the...

Private Pilot Practical Test Standards for Rotorcraft - Helicopter, Gyroplane

DOT National Transportation Integrated Search

1996-04-01

The Private Pilot - Rotorcraft (Helicopter and Gyroplane) Practical Test Standards (PTS) book has been published by the Federal Aviation Administration (FAA) to establish the standards for private pilot certification practical tests for the rotorcraf...

Research on computer aided testing of pilot response to critical in-flight events

NASA Technical Reports Server (NTRS)

Giffin, W. C.; Rockwell, T. H.; Smith, P. J.

1984-01-01

Experiments on pilot decision making are described. The development of models of pilot decision making in critical in flight events (CIFE) are emphasized. The following tests are reported on the development of: (1) a frame system representation describing how pilots use their knowledge in a fault diagnosis task; (2) assessment of script norms, distance measures, and Markov models developed from computer aided testing (CAT) data; and (3) performance ranking of subject data. It is demonstrated that interactive computer aided testing either by touch CRT's or personal computers is a useful research and training device for measuring pilot information management in diagnosing system failures in simulated flight situations. Performance is dictated by knowledge of aircraft sybsystems, initial pilot structuring of the failure symptoms and efficient testing of plausible causal hypotheses.

Private Pilot Practical Test Standards for Lighter-Than-Air Balloon, Airship

DOT National Transportation Integrated Search

1996-06-01

The Private Pilot - Lighter-Than-Air (Balloon and Airship) Practical Test Standards (PTS) book has been published by the Federal Aviation Administration (FAA) to establish the standards for private pilot certification practical tests for the lighter-...

Private Pilot Practical Test Standards for Airplane (SEL, MEL, SES, MES)

DOT National Transportation Integrated Search

1995-05-01

The Private Pilot - Airplane Practical Test Standards book has been : published by the Federal Aviation Administration (FAA) to establish the : standards for the private pilot certification practical tests for the airplane : category and the single-e...

Commercial Pilot Practical Test Standards for Lighter-Than-Air Balloon, Airship

DOT National Transportation Integrated Search

1997-05-01

The Commercial Pilot Lighter-Than-Air Practical Test Standards (PTS) book has been published by the Federal Aviation Administration (FAA) to establish the standards for commercial pilot certification practical tests for the lighter-than-air category,...

Field-Scale Evaluation of Monitored Natural Attenuation for Dissolved Chlorinated Solvent Plumes

DTIC Science & Technology

2009-04-01

biological in-situ treatment, an air sparging pilot study, and a phytoremediation study. The innovative technology studies were conducted within the source... phytoremediation (June to September 1997), reductive anaerobic biological in-situ treatment technology (RABITT; 1998), and groundwater recirculation wells...u g / L ) Measured Concentrations in 1381MWS09 Air Sparge Pilot Test (1996/1997) Phytoremediation Pilot Test (1997) RABITT Pilot Test (1998

HIV testing for acute medical admissions: evaluation of a pilot study in Leicester, England.

PubMed

Palfreeman, Adrian; Nyatsanza, Farai; Farn, Helen; McKinnon, Graham; Schober, Paul; McNally, Paul

2013-06-01

The 2008 UK National Guidelines for HIV testing recommended HIV testing should be offered to all general medical admissions aged 16-60 years in high prevalence areas, and that this should be evaluated to ensure this was effective in diagnosing previously undiagnosed HIV. HIV testing was introduced as a routine test for all patients admitted to the acute medical admissions unit, comparisons were made between the testing rates before, during and after this intervention. The pilot was initiated in August 2009. Prior to the pilot the unit was carrying out 15 tests per month. However, when the pilot was introduced 82 tests were being carried out per month with a total of 10 new diagnoses since the start of the pilot. The proportion of patients tested versus those eligible for testing remained low varying between 6% and 22% month by month. 10 patients we found to be HIV positive with a prevalence of approximately 1%, 10 fold higher than the cut off for cost effectiveness used in the guidelines. Overall the pilot showed that HIV testing could be delivered without the use of extra resources and is acceptable to patients.

A randomized controlled pilot study of VO2 max testing: a potential model for measuring relative in vivo efficacy of different red blood cell products.

PubMed

Bennett-Guerrero, Elliott; Lockhart, Evelyn L; Bandarenko, Nicholas; Campbell, Mary L; Natoli, Michael J; Jamnik, Veronika K; Carter, Timothy R; Moon, Richard E

2017-03-01

Randomized trials, for example, RECESS, comparing "young" (median, 7-day) versus "middle-aged" (median, 28-day) red blood cells (RBCs), showed no difference in outcome. These data are important; however, they do not inform us about the safety and effectiveness of the oldest RBCs, which some patients receive. It may not be feasible to conduct a clinical trial randomizing patients to receive the oldest blood. Therefore, we propose strenuous exercise (VO 2 max testing) as a model to study the relative efficacy to increase oxygen delivery to tissue of different RBC products, for example, extremes of storage duration. In this pilot study, eight healthy subjects had 2 units of leukoreduced RBCs collected by apheresis in AS-3 using standard methods. Subjects were randomized to receive both (2) units of their autologous RBCs at either 7 or 42 days after blood collection. VO 2 max testing on a cycle ergometer was performed 2 days before (Monday) and 2 days after (Friday) the transfusion visit (Wednesday). This design avoids confounding effects on intravascular volume from the 2-unit blood transfusion. The primary outcome was the difference in VO 2 max between Friday and Monday (delta VO 2 max). VO 2 max increased more in the 7-day RBC arm (8.7 ± 6.9% vs. 1.9 ± 6.5%, p = 0.202 for comparison between arms). Exercise duration (seconds) increased in the 7-day RBC arm (8.4 ± 1.7%) but actually decreased in the 42-day arm (-2.6 ± 3.6%, p = 0.002). This pilot study suggests that VO 2 max testing has potential as a rigorous and quantitative in vivo functional assay of RBC function. Our preliminary results suggest that 42-day RBCs are inferior to 7-day RBCs at delivering oxygen to tissues. © 2016 AABB.

Study of occupational stress among railway engine pilots

PubMed Central

Kumar, Devesh; Singh, Jai Vir; Kharwar, Poonam S.

2011-01-01

Background: Traffic volume and speed is going to be increased in Indian Railways successively, leading to higher stress in staff connected with train operations. The jobs of railway engine pilots come under the category of high-strain jobs, necessitating a need to conduct multicentric study to unfold the factors associated with occupational stress and organizational strategies. Materials and Methods: Present study covered 185 railway engine pilots and office clerks working in various railway zones by incidental method. Occupational Stress Index (OSI) test developed by Srivastva and Singh, questionnaire of specific stressors constructed by authors and laboratory test battery for psychological screening of high-speed train pilots were used as tools. Results: Means of OSI and all the 12 occupational stressors of railway engine pilots were found significantly higher to that of office clerks. Means of OSI and occupational stressors of goods train pilots were significantly higher in comparison to high-speed train pilots and passenger train pilots. Study revealed positive correlation of speed perception and complex reaction time tests and negative correlation of other constituent tests of laboratory test battery to OSI test. Highest subgroup of stressor observedwas role overload followed by role conflict. Conclusions: These findings provide a prima facie evidence of higher occupational stress among railway engine pilots because of identified specific stressors prevalent in their job and explore the possible intervention strategies for its reduction. Significant correlation is noticed between OSI and laboratory test results, indicating its relevant utility in preliminary psychological screening. PMID:21808497

Staff views of an opportunistic chlamydia testing pilot in a primary health organisation.

PubMed

McKernon, Stephen; Azariah, Sunita

2013-12-01

The Auckland chlamydia pilot was one of three pilots funded by the Ministry of Health to trial implementation of the 2008 Chlamydia Management Guidelines prior to national roll-out. To assess what elements in the testing programme pilot worked best for staff and to determine how an opportunistic testing programme could be better configured to meet staff needs and preferences. A staff survey listed key chlamydia testing tasks in chronological order, and service interventions supporting these tasks. Staff were asked to rate each task on its difficulty prior to the pilot, and then on the difference the pilot had made to each task. They were also asked to rate service interventions on their usefulness during the pilot implementation. The survey had a response rate of 94%. The testing tasks posing the greatest difficulties to staff were those involving patient interactions (41%) and management of follow-up (52%). About 70% of staff felt tasks were improved by the pilot. Staff considered the three most useful service interventions to be a chlamydia-specific template created for the practice management system, provision of printed patient resources, and regular team discussions with other staff. A significant proportion of staff reported difficulties with routine tasks required for opportunistic testing for chlamydia, highlighting the need to involve staff during programme design. Practice nurse-led approaches to future opportunistic testing programmes should be considered as nurses had a more positive response to the pilot and nurse-led approaches have been shown to be successful overseas.

Assessment of Muscular Fitness as a Predictor of Flight Duty Limitation.

PubMed

Honkanen, Tuomas; Mäntysaari, Matti; Avela, Janne; Kyröläinen, Heikki; Leino, Tuomo

2018-05-08

The high acceleration (Gz) exposure among military pilots flying fighter aircraft has been associated with an increased risk for cervical and lumbar disorders. It has been suggested that an adequate level of physical performance could reduce the risk of experiencing these disorders. The Finnish Air Force has for several years used aerobic (bicycle ergometer) and muscular fitness tests (battery of five tests) in the selection process of military pilot candidates in order to evaluate their physical fitness level. The aim of the study was to determine if these selection phase tests and anthropometry measures can predispose those individuals who might be at risk of developing severe spinal disorders leading to permanent flight duty limitations later during their military pilots' career. The study population consisted of 23 pilots flying with Gz limitation (+2 Gz, +4 Gz or +5 Gz) due to spinal disorders and 50 experienced (+1,000 flight hours) symptomless controls flying actively in operative missions. Data obtained retrospectively for all subjects included anthropometry, physical (aerobic and muscular fitness) test results and self-reported physical activity levels at a pilot selection phase. Aerobic fitness was measured with a maximal ergometer test and muscular endurance was evaluated with a test battery (standing long jump, pull-ups, sit-ups, back extensions, and push-up tests). Fighter pilots flying without Gz limitation had significantly better mean (±SE) results in pull-up (14.4 ± 4.2 vs. 11.5 ± 2.0, p < 0.05) and back extension (71.1 ± 14.1 vs. 60.0 ± 12.2, p < 0.05) tests during the pilot selection when compared with the limited pilots. Similarly, the non-limited pilots had a better total muscular fitness test score (13.7 ± 1.7 vs. 12.4 ± 1.6, p < 0.05) during the pilot selection. They had also participated in significantly more competitive sports (54% vs. 22%, p < 0.05) at the time of selection when compared with pilots flying with Gz limitation due to spinal disorders. The aerobic fitness test results and anthropometric measures were not statistically different among the groups. Higher levels of muscular fitness, particularly axial strength in military pilot selection may have a protective role for reducing spinal disorders which if developed, can often lead to limiting the availability of pilots for flight duty. The present findings also do not support the assumption that aerobic fitness above the required minimum level would protect pilots from developing spinal disorders and, therefore, from limiting flight duty.

14 CFR 61.157 - Flight proficiency.

Code of Federal Regulations, 2010 CFR

2010-01-01

... CERTIFICATION: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS Airline Transport Pilots § 61.157 Flight proficiency. (a) General. (1) The practical test for an airline transport pilot certificate is given for— (i...) An aircraft type rating. (2) A person who is applying for an airline transport pilot practical test...

Airline Transport Pilot and/or Type Rating - Practical Test Standards for Airplane, Helicopter

DOT National Transportation Integrated Search

1995-07-01

The Airline Transport Pilot and/or Type Rating Practical Test Standards : (PTS) book has been published by the Federal Aviation Administration : (FAA) to establish the standards for Airline Transport Pilot and Type Rating : practical tests for airpla...

In vitro Antiproliferative Effect of Earthworm Coelomic Fluid of Eudrilus Eugeniae, Eisenia Foetida, and Perionyx Excavatus on Squamous Cell Carcinoma-9 Cell Line: A Pilot Study.

PubMed

Augustine, Dominic; Rao, Roopa S; Anbu, Jayaraman; Chidambara Murthy, K N

2017-12-01

The earthworm coelomic fluid (ECF) has shown proven antiproliferative effect against breast, liver, gastrointestinal, and brain cancer, but it is least explored in oral cancer. The present in vitro study is an attempt to investigate the antiproliferative activity of ECF on oral cancer cell line squamous cell carcinoma (SCC)-9. ECF was collected from the species Eudrilus eugeniae (EE), Eisenia foetida (EF), and Perionyx excavatus (PE) stored at -80°C. Percentage inhibition of ECF on squamous cell carcinoma-9 cells in vitro was recorded at 24 h. Protein estimation was done using Bradford protein assay validated by the biuret method. Cytotoxicity was tested at 2.5, 5, 10, 20, 40, and 80 μg/ml concentrations by 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide assay in SCC-9 cells in vitro . GraphPad Prism 7.0 software was used to calculate the inhibitory concentration (IC 50 ). Chi-square test was used to analyze the difference between samples. The test samples EE, EF, and PE inhibited the growth of SCC-9 cells significantly in a dose-dependent manner, and the IC 50 values were found to be 4.6, 44.69, and 5.27 μg/ml, respectively. The antiproliferative effect was found to be variable among the three earthworm species with EE showing the most promising effect followed by PE and EF. Establishing the antiproliferative effect of ECF on oral cancer cells could be an initial step toward drug development and future anticancer research. The preliminary investigation has shown that ECF has a promising antiproliferative effect on oral cancer cells in vitro . The present pilot study evaluated the in vitro antiproliferative effect of earthworm coelomic fluid (ECF) of Eudrilus eugeniae (EE), Eisenia foetida (EF), and Perionyx excavatus (PE) on squamous cell carcinoma-9 cell line. The ECF inhibitory activity was promising at inhibitory concentration values of 4.6, 44.69, and 5.27 μg/ml, respectively. Further studies pertaining to antiproliferative mechanism of EE, EF, and PE have been planned. Abbreviations Used: ECF: Earthworm coelomic fluid, EE: Eudrilus eugeniae , EF: Eisenia foetida , PE: Perionyx excavatus , MTT: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, SCC: Squamous cell carcinoma, BSA: Bovine serum albumin, PBS: Phosphored buffered saline, ATCC: American Type Culture Collection.

Grade 9 Pilot Test. Mathematics. June 1988 = 9e Annee Test Pilote. Mathematiques. Juin 1988.

ERIC Educational Resources Information Center

Alberta Dept. of Education, Edmonton.

This pilot test for ninth grade mathematics is written in both French and English. The test consists of 75 multiple-choice items. Students are given 90 minutes to complete the examination and the use of a calculator is highly recommended. The test content covers a wide range of mathematical topics including: decimals; exponents; arithmetic word…

Neural Network Modeling of UH-60A Pilot Vibration

NASA Technical Reports Server (NTRS)

Kottapalli, Sesi

2003-01-01

Full-scale flight-test pilot floor vibration is modeled using neural networks and full-scale wind tunnel test data for low speed level flight conditions. Neural network connections between the wind tunnel test data and the tlxee flight test pilot vibration components (vertical, lateral, and longitudinal) are studied. Two full-scale UH-60A Black Hawk databases are used. The first database is the NASMArmy UH-60A Airloads Program flight test database. The second database is the UH-60A rotor-only wind tunnel database that was acquired in the NASA Ames SO- by 120- Foot Wind Tunnel with the Large Rotor Test Apparatus (LRTA). Using neural networks, the flight-test pilot vibration is modeled using the wind tunnel rotating system hub accelerations, and separately, using the hub loads. The results show that the wind tunnel rotating system hub accelerations and the operating parameters can represent the flight test pilot vibration. The six components of the wind tunnel N/rev balance-system hub loads and the operating parameters can also represent the flight test pilot vibration. The present neural network connections can significandy increase the value of wind tunnel testing.

The effects of display and autopilot functions on pilot workload for Single Pilot Instrument Flight Rule (SPIFR) operations

NASA Technical Reports Server (NTRS)

Hoh, Roger H.; Smith, James C.; Hinton, David A.

1987-01-01

An analytical and experimental research program was conducted to develop criteria for pilot interaction with advanced controls and displays in single pilot instrument flight rules (SPIFR) operations. The analytic phase reviewed fundamental considerations for pilot workload taking into account existing data, and using that data to develop a divided attention SPIFR pilot workload model. The pilot model was utilized to interpret the two experimental phases. The first experimental phase was a flight test program that evaluated pilot workload in the presence of current and near-term displays and autopilot functions. The second experiment was conducted on a King Air simulator, investigating the effects of co-pilot functions in the presence of very high SPIFR workload. The results indicate that the simplest displays tested were marginal for SPIFR operations. A moving map display aided the most in mental orientation, but had inherent deficiencies as a stand alone replacement for an HSI. Autopilot functions were highly effective for reducing pilot workload. The simulator tests showed that extremely high workload situations can be adequately handled when co-pilot functions are provided.

Instrument Pilot: Airplane. Flight Test Guide, Part 61 Revised 1973, AC 61-56.

ERIC Educational Resources Information Center

Federal Aviation Administration (DOT), Washington, DC. Flight Standards Service.

This flight test guide is designed to assist the applicant and his instructor in preparing for the flight test for Instrument Pilot Airplane Rating under Part 61 (revised) of Federal Aviation Regulations. It contains information concerning pilot operations, procedures, and maneuvers relevant to the flight test required for the Instrument Rating.…

Large increase in opportunistic testing for chlamydia during a pilot project in a primary health organisation.

PubMed

Azariah, Sunita; McKernon, Stephen; Werder, Suzanne

2013-06-01

The Auckland chlamydia pilot project was one of three funded by the Ministry of Health to trial implementation of the 2008 Chlamydia Management Guidelines. Chlamydia is the most commonly notified sexually transmitted infection in New Zealand. To increase opportunistic testing in under-25-year-olds and to improve documentation of partner notification in primary care. A four-month pilot was initiated in Total Healthcare Otara using a nurse-led approach. Laboratory testing data was analysed to assess whether the pilot had any impact on chlamydia testing volumes in the target age-group. Data entered in the practice management system was used to assess follow-up and management of chlamydia cases. During the pilot there was a 300% increase in the number of chlamydia tests in the target age group from 812 to 2410 and the number of male tests increased by nearly 500%. Twenty-four percent of people tested were positive for chlamydia, with no significant difference in prevalence by ethnicity. The pilot resulted in better documentation of patient follow-up in the patient management system. There was a large increase in chlamydia testing during the pilot with a high prevalence found in the population tested. Chlamydia remains an important health problem in New Zealand. The cost benefit of increased chlamydia screening at a population level has yet to be established.

Contracting and Monitoring Relationships for Adolescents with Type 1 Diabetes: A Pilot Study

PubMed Central

DiMeglio, Linda A.; Stein, Stephanie; Marrero, David G.

2011-01-01

Abstract Background Adolescents are developmentally in a period of transition—from children cared for by their parents to young adults capable of self-care, independent judgment, and self-directed problem solving. We wished to develop a behavioral contract for adolescent diabetes management that addresses some negotiable points of conflict within the parent–child relationship regarding self-monitoring and then assess its effectiveness in a pilot study as part of a novel cell phone–based glucose monitoring system. Methods In the first phase of this study we used semistructured interview techniques to determine the major sources of diabetes-related conflict in the adolescent–parent relationship, to identify factors that could facilitate or inhibit control, and to determine reasonable goals and expectations. These data were then used to inform development of a behavioral contract that addressed the negotiable sources of conflict between parents and their adolescent. The second phase of this research was a 3-month pilot study to measure how a novel cell phone glucose monitoring system would support the contract and have an effect on glucose management, family conflict, and quality of life. Results Interviews were conducted with 10 adolescent–caregiver pairs. The major theme of contention was nagging about diabetes management. Two additional themes emerged as points of negotiation for the behavioral contract: glucose testing and contact with the diabetes clinical team. Ten adolescent–parent pairs participated in the pilot test of the system and contract. There was a significant improvement in the Diabetes Self-Management Profile from 55.2 to 61.1 (P < 0.01). A significant reduction in hemoglobin A1c also occurred, from 8.1% at the start of the trial to 7.6% at 3 months (P < 0.04). Conclusions This study confirms previous findings that mobile technologies do offer significant potential in improving the care of adolescents with type 1 diabetes. Moreover, behavioral contracts may be an important adjunct to reduce nagging and improve outcomes with behavioral changes. PMID:21406011

Specifically Designed Constructed Wetlands: A Novel Treatment Approach for Scrubber Wastewater

DOE Office of Scientific and Technical Information (OSTI.GOV)

John H. Rodgers Jr; James W. Castle; Chris Arrington: Derek Eggert

2005-09-01

A pilot-scale wetland treatment system was specifically designed and constructed at Clemson University to evaluate removal of mercury, selenium, and other constituents from flue gas desulfurization (FGD) wastewater. Specific objectives of this research were: (1) to measure performance of a pilot-scale constructed wetland treatment system in terms of decreases in targeted constituents (Hg, Se and As) in the FGD wastewater from inflow to outflow; (2) to determine how the observed performance is achieved (both reactions and rates); and (3) to measure performance in terms of decreased bioavailability of these elements (i.e. toxicity of sediments in constructed wetlands and toxicity ofmore » outflow waters from the treatment system). Performance of the pilot-scale constructed wetland treatment systems was assessed using two criteria: anticipated NPDES permit levels and toxicity evaluations using two sentinel toxicity-testing organisms (Ceriodaphnia dubia and Pimephales promelas). These systems performed efficiently with varied inflow simulations of FGD wastewaters removing As, Hg, and Se concentrations below NPDES permit levels and reducing the toxicity of simulated FGD wastewater after treatment with the constructed wetland treatment systems. Sequential extraction procedures indicated that these elements (As, Hg, and Se) were bound to residual phases within sediments of these systems, which should limit their bioavailability to aquatic biota. Sediments collected from constructed wetland treatment systems were tested to observe toxicity to Hyalella azteca or Chironomus tetans. Complete survival (100%) was observed for H. azteca in all cells of the constructed wetland treatment system and C. tentans had an average of 91% survival over the three treatment cells containing sediments. Survival and growth of H. azteca and C. tentans did not differ significantly between sediments from the constructed wetland treatment system and controls. Since the sediments of the constructed wetland treatment system are repositories for As, Hg, and Se and the bioavailability of these elements decreased after deposition, the pilot-scale constructed wetland treatment system contributed significantly to mitigation of risks to aquatic life from these elements.« less

Ball Powder Production Wastewater Biodegradation Support Studies - With Nitroglycerine

DTIC Science & Technology

1989-02-01

in the wastewater. Characterization of the ball powder wastewater stream showed an actual average NG inlet concentration of 192 mg/L. Pilot test...the first phase of pilot testing, the recommendation was made to conduct an additional pilot test phase to determine the effect of nitroglycerin (NG...NG by aerobic bacteria, a pilot program was undertaken with the following objectives: 1) to determine the concentration of NG in the ball powder

Pilot Study: Foam Wedge Chin Support Static Tolerance Testing

DTIC Science & Technology

2017-10-24

AFRL-SA-WP-SR-2017-0026 Pilot Study : Foam Wedge Chin Support Static Tolerance Testing Austin M. Fischer, BS1; William W...COVERED (From – To) April – October 2017 4. TITLE AND SUBTITLE Pilot Study : Foam Wedge Chin Support Static Tolerance Testing 5a. CONTRACT NUMBER...prototype to mitigate the increase in helmet weight and forward center of gravity. The purpose of this pilot study was to determine the feasibility and

78 FR 34423 - Aviation Rulemaking Advisory Committee (ARAC) Airman Testing Standards and Training Working Group...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-07

... private pilot certificate and the instrument rating. These documents are available for public review... Airman Testing Standards and Training (2) Draft PRIVATE PILOT--AIRPLANE Airman Certification Standards; (3) Draft Change Tracking Matrix referenced to FAA-S-8081-14B, Private Pilot Practical Test Standards...

Flight Test Guide (Part 61 Revised): Instrument Pilot: Helicopter.

ERIC Educational Resources Information Center

Federal Aviation Administration (DOT), Washington, DC. Flight Standards Service.

The guide provides an outline of the skills required to pass the flight test for an Instrument Pilot Helicopter Rating under Part 61 (revised) of Federal Aviation Regulations. General procedures for flight tests are described and the following pilot operations outlined: maneuvering by reference to instruments, IFR navigation, instrument…

Performance of a pilot-scale continuous flow microbial electrolysis cell fed winery wastewater.

PubMed

Cusick, Roland D; Bryan, Bill; Parker, Denny S; Merrill, Matthew D; Mehanna, Maha; Kiely, Patrick D; Liu, Guangli; Logan, Bruce E

2011-03-01

A pilot-scale (1,000 L) continuous flow microbial electrolysis cell was constructed and tested for current generation and COD removal with winery wastewater. The reactor contained 144 electrode pairs in 24 modules. Enrichment of an exoelectrogenic biofilm required ~60 days, which is longer than typically needed for laboratory reactors. Current generation was enhanced by ensuring adequate organic volatile fatty acid content (VFA/SCOD ≥ 0.5) and by raising the wastewater temperature (31 ± 1°C). Once enriched, SCOD removal (62 ± 20%) was consistent at a hydraulic retention time of 1 day (applied voltage of 0.9 V). Current generation reached a maximum of 7.4 A/m(3) by the planned end of the test (after 100 days). Gas production reached a maximum of 0.19 ± 0.04 L/L/day, although most of the product gas was converted to methane (86 ± 6%). In order to increase hydrogen recovery in future tests, better methods will be needed to isolate hydrogen gas produced at the cathode. These results show that inoculation and enrichment procedures are critical to the initial success of larger-scale systems. Acetate amendments, warmer temperatures, and pH control during startup were found to be critical for proper enrichment of exoelectrogenic biofilms and improved reactor performance.

Assessment of simulation fidelity using measurements of piloting technique in flight

NASA Technical Reports Server (NTRS)

Clement, W. F.; Cleveland, W. B.; Key, D. L.

1984-01-01

The U.S. Army and NASA joined together on a project to conduct a systematic investigation and validation of a ground based piloted simulation of the Army/Sikorsky UH-60A helicopter. Flight testing was an integral part of the validation effort. Nap-of-the-Earth (NOE) piloting tasks which were investigated included the bob-up, the hover turn, the dash/quickstop, the sidestep, the dolphin, and the slalom. Results from the simulation indicate that the pilot's NOE task performance in the simulator is noticeably and quantifiably degraded when compared with the task performance results generated in flight test. The results of the flight test and ground based simulation experiments support a unique rationale for the assessment of simulation fidelity: flight simulation fidelity should be judged quantitatively by measuring pilot's control strategy and technique as induced by the simulator. A quantitative comparison is offered between the piloting technique observed in a flight simulator and that observed in flight test for the same tasks performed by the same pilots.

14 CFR 61.307 - What tests do I have to take to obtain a sport pilot certificate?

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false What tests do I have to take to obtain a sport pilot certificate? 61.307 Section 61.307 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... a sport pilot certificate, you must pass the following tests: (a) Knowledge test. You must pass a...

14 CFR 61.307 - What tests do I have to take to obtain a sport pilot certificate?

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false What tests do I have to take to obtain a sport pilot certificate? 61.307 Section 61.307 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... a sport pilot certificate, you must pass the following tests: (a) Knowledge test. You must pass a...

YF-12A #935 with test pilot Donald L. Mallick

NASA Technical Reports Server (NTRS)

1972-01-01

NASA test pilot Don Mallick, in full pressure suit, stands in front of the YF-12A (60-6935). Don is ready for a flight across the Western United States. Donald L. Mallick joined the National Advisory Committee for Aeronautics' Langley Aeronautical Laboratory at Hampton, Virginia, as a research pilot, in June 1957. He transferred to the National Aeronautics and Space Administration's Flight Research Center, Edwards, California, in February 1963. Mallick attended Pennsylvania State University, University Park, Pennsylvania, for the period 1948-1949, studying Mechanical Engineering before entering the U.S. Navy for pilot training. Don served during the Korean War period, 1950-1954, flying F2H-2 Banshee jets from the carriers, USS F.D. Roosevelt and the USS Wasp. Later in 1954 he returned to school at the University of Florida, Gainesville, Florida, graduating with Honors in June 1957 and earning his degree in aeronautical engineering. Don joined the Naval Reserves and served in almost all categories of Reserve operations before retiring in 1970 as a Lieutenant Commander. As a research pilot at NACA-NASA Langley Don flew quantitative stability-&-control and handling-qualities tests on modified helicopters. On the Vertol VZ-2 Vertical Short Take-off and Landing research aircraft, he performed qualitative evaluation flights. Other aircraft flown for flight tests were: F2H-1 Banshee, F-86D, F9F-2 and F8U-3, F11F-1 Tigercat, and F-100C. Don also flew support and photo flights. In his capacity as research pilot at the NASA Flight Research Center Don was assigned to NASA's Lockheed Jetstar General Purpose Airborne Simulator (GPAS). He flew all of the tests, with the majority being as project pilot. Mallick made a flight in the lightweight M2-F1 lifting body on January 30, 1964. In 1964, Don was assigned to and completed the USAF Test pilot school, Class 64A. Later in 1964, he flew as the co-project pilot on the Lunar Landing Research Vehicle (LLRV) making over seventy flights including the first using the three-axis side controller. In 1967, he was assigned to fly as one of two NASA pilots on the joint NASA-USAF XB-70 flight test program. Don flew as one of two NASA test pilots on the NASA YF-12A and YF-12C test programs accumulating 215 hours in 105 flights of test time in the triple-sonic Blackbirds. He was project pilot on both programs. Mallick was appointed Chief Pilot of the Flight Research Center in 1967, a position that he held for fourteen years. He was proud of the fact that during this period he flew himself and also directed six other NASA test pilots without a fatal accident. In 1981, he became Deputy Chief of the Aircraft Operations Division. Don retired April 3, 1987, after logging over 11,000 flight hours in more than 125 different types of aircraft and helicopters. Mallick has written several reports. In 1975, he was selected and honored as a Fellow in the Society of Experimental Test Pilots, of which he is still a member.

Fighter pilots' heart rate, heart rate variation and performance during an instrument flight rules proficiency test.

PubMed

Mansikka, Heikki; Virtanen, Kai; Harris, Don; Simola, Petteri

2016-09-01

Increased task demand will increase the pilot mental workload (PMWL). When PMWL is increased, mental overload may occur resulting in degraded performance. During pilots' instrument flight rules (IFR) proficiency test, PMWL is typically not measured. Therefore, little is known about workload during the proficiency test and pilots' potential to cope with higher task demands than those experienced during the test. In this study, fighter pilots' performance and PMWL was measured during a real IFR proficiency test in an F/A-18 simulator. PMWL was measured using heart rate (HR) and heart rate variation (HRV). Performance was rated using Finnish Air Force's official rating scales. Results indicated that HR and HRV differentiate varying task demands in situations where variations in performance are insignificant. It was concluded that during a proficiency test, PMWL should be measured together with the task performance measurement. Copyright © 2016 Elsevier Ltd. All rights reserved.

Embryo selection using time-lapse analysis (Early Embryo Viability Assessment) in conjunction with standard morphology: a prospective two-center pilot study.

PubMed

Kieslinger, Dorit C; De Gheselle, Stefanie; Lambalk, Cornelis B; De Sutter, Petra; Kostelijk, E Hanna; Twisk, Jos W R; van Rijswijk, Joukje; Van den Abbeel, Etienne; Vergouw, Carlijn G

2016-11-01

Does prospective embryo selection using the results from the Eava Test (Early Embryo Viability Assessment) in combination with standard morphology increase the pregnancy rate of IVF and ICSI patients compared to embryo selection based on morphology only? Embryo selection using the Eeva Test plus standard morphology on Day 3 results in comparable pregnancy rates as conventional morphological embryo selection. Time-lapse monitoring of embryo development may represent a superior way to culture and select embryos in vitro. The Eeva Test records the development of each embryo with a cell-tracking system and predicts the likelihood (High, Medium or Low) that an embryo will form a blastocyst based on an automated analysis of early cell division timings. This trial was designed as a prospective, observational, two-center pilot study with a propensity matched control group. The analysis involved 280 of 302 enrolled patients who were included in the Eeva Test group in 2013 and 560 control patients who were treated in the years 2011-2013. The majority of transfers (98%) were single embryo transfers. Two academic hospitals (VUmc Amsterdam and UZ Gent) enrolled patients <41 years old, with <3 previous attempts and ≥5 normally fertilized eggs. Propensity matching was used to identify a propensity matched control group from a cohort of 1777 patients based on age, cycle number, oocyte number and number of fertilized oocytes. There was no difference in patient baseline characteristics between the two groups. The ongoing pregnancy rate (OPR) of patients enrolled in the Eeva Test group (34.3%; 96/280) did not differ significantly from the OPR in the propensity matched control group (34.6%, 194/560; P = 0.92). However, significantly less top quality embryos (eight-cell embryos with ≤25% fragmentation) were transferred in the Eeva Test group compared to the propensity matched control group (70.4% vs. 82.3%; P < 0.001). The transfer of Eeva High and Medium embryos resulted in a significantly higher OPR of 36.8% (89/242) compared to 18.4% (7/38) for Eeva Low embryos (P = 0.02). This pilot study is limited by its nonrandomized design with a concurrent and historical control. Our pilot data did not reveal significant differences between time-lapse based and conventional embryo selection. Interestingly, the pregnancy rates were comparable in both groups even though the morphological quality of the transferred embryos was significantly lower in the Eeva Test group compared to the propensity matched control group. A sufficiently powered three-armed randomized controlled trial (RCT) with a solid design should be performed to generate decisive evidence in the future. Progyny Inc., formerly Auxogyn provided the Eeva scopes, software and technical support for this study. The funding sources did neither influence data collection, management, analysis and interpretation of the data, nor the preparation of the manuscript. ClinicalTrials.gov: NCT01671644. © The Author 2016. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Private and Commercial Pilot; Heliocoptor. Flight Test Guide, Part 61 Revised, AC 61-59.

ERIC Educational Resources Information Center

Federal Aviation Administration (DOT), Washington, DC. Flight Standards Service.

This flight test guide assists the applicant and his instructor in preparing for the Private or Commercial Pilot Rotocraft Certificate with Helicopter Rating under Part 61 (revised) of Federal Aviation Regulations. It contains information and guidance concerning the pilot operations, procedures, and maneuvers relevant to the flight test required…

Principles of Technology. Units 1-10 Pilot Test Findings.

ERIC Educational Resources Information Center

Center for Occupational Research and Development, Inc., Waco, TX.

This document provides the findings of pilot tests of 10 units for an applied science course for high school vocational students. Each of the reports on the pilot tests of the Principles of Technology units contains information on procedures, methodology limitations, sample, the pretest/posttest instrument and results, student attitude results,…

Treatment of the Cerro Prieto I brines for use in reinjection. 2. Results of the pilot plant tests

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hurtado J, R.; Mercado G, S.; Rocha C, E.

Silica removal experiments have been carried out both in the laboratory and in pilot scale tests. The results obtained to date are presented, with special emphasis on the pilot tests with or without the use of flocculants. Previous studies on brine treatment are described briefly.

Flight Test Guide (Part 61 Revised); Private Pilot Airplane.

ERIC Educational Resources Information Center

Federal Aviation Administration (DOT), Washington, DC. Flight Standards Service.

This guide provides an outline of the skills required to pass the flight test for a Private Pilot Certificate with Airplane Rating under part 61 (revised) of Federal Aviation Regulations. General procedures for flight tests are described and the following pilot operations outlined: preflight operations, airport and traffic pattern operations,…

Recreational Pilot Practical Test Standards for Airplane, Rotorcraft

DOT National Transportation Integrated Search

1989-04-01

The Aviation Standards National Field Office of the FAA has : developed this book to be used as a standard by FAA inspectors : and designated pilot examiners when conducting recreational pilot : airmen practical tests. Flight instructors are expected...

Piloted simulation study of an ILS approach of a twin-pusher business/commuter turboprop aircraft configuration

NASA Technical Reports Server (NTRS)

Riley, Donald R.; Brandon, Jay M.; Glaab, Louis J.

1994-01-01

A six-degree-of-freedom nonlinear simulation of a twin-pusher, turboprop business/commuter aircraft configuration representative of the Cessna ATPTB (Advanced turboprop test bed) was developed for use in piloted studies with the Langley General Aviation Simulator. The math models developed are provided, simulation predictions are compared with with Cessna flight-test data for validation purposes, and results of a handling quality study during simulated ILS (instrument landing system) approaches and missed approaches are presented. Simulated flight trajectories, task performance measures, and pilot evaluations are presented for the ILS approach and missed-approach tasks conducted with the vehicle in the presence of moderate turbulence, varying horizontal winds and engine-out conditions. Six test subjects consisting of two research pilots, a Cessna test pilot, and three general aviation pilots participated in the study. This effort was undertaken in cooperation with the Cessna Aircraft Company.

Instrument Rating Knowledge Test Guide

DOT National Transportation Integrated Search

1995-01-01

The FAA has available hundreds of computer testing centers nationwide. These testing centers offer the full range of airman knowledge tests including military competence, instrument foreign pilot, and pilot examiner predesignated tests. Refer to appe...

Feasibility and usability of a text message-based program for diabetes self-management in an urban African-American population.

PubMed

Dick, Jonathan J; Nundy, Shantanu; Solomon, Marla C; Bishop, Keisha N; Chin, Marshall H; Peek, Monica E

2011-09-01

We pilot-tested a text message-based diabetes care program in an urban African-American population in which automated text messages were sent to participants with personalized medication, foot care, and appointment reminders and text messages were received from participants on adherence. Eighteen patients participated in a 4-week pilot study. Baseline surveys collected data about demographics, historical cell phone usage, and adherence to core diabetes care measures. Exit interview surveys (using close-coded and open-ended questions) were administered to patients at the end of the program. A 1-month follow-up interview was conducted surveying patients on perceived self-efficacy. Wilcoxon signed-rank tests were used to compare baseline survey responses about self-management activities to those at the pilot's end and at 1-month follow-up. Eighteen urban African-American participants completed the pilot study. The average age was 55 and the average number of years with diabetes was 8. Half the participants were initially uncomfortable with text messaging. Example messages include "Did you take your diabetes medications today" and "How many times did you check your feet for wounds this week?" Participants averaged 220 text messages with the system, responded to messages 80% of the time, and on average responded within 6 minutes. Participants strongly agreed that text messaging was easy to perform and helped with diabetes self-care. Missed medication doses decreased from 1.6 per week to 0.6 (p = .003). Patient confidence in diabetes self-management was significantly increased during and 1 month after the pilot (p = .002, p = .008). Text messaging may be a feasible and useful approach to improve diabetes self-management in urban African Americans. © 2011 Diabetes Technology Society.

Aerial pesticide application causes DNA damage in pilots from Sinaloa, Mexico.

PubMed

Martínez-Valenzuela, C; Waliszewski, S M; Amador-Muñoz, O; Meza, E; Calderón-Segura, M E; Zenteno, E; Huichapan-Martínez, J; Caba, M; Félix-Gastélum, R; Longoria-Espinoza, R

2017-01-01

The use of pesticides in agricultural production originates residues in the environment where they are applied. Pesticide aerial application is a frequent source of exposure to pesticides by persons dedicated to agricultural practices and those living in neighboring communities of sprayed fields. The aim of the study was to assess the genotoxic effects of pesticides in workers occupationally exposed to these chemicals during their aerial application to agricultural fields of Sinaloa, Mexico. The study involved 30 pilots of airplanes used to apply pesticides via aerial application and 30 unexposed controls. Damage was evaluated through the micronucleus assay and by other nuclear abnormalities in epithelial cells of oral mucosa. The highest frequency ratios (FR) equal to 269.5 corresponded to binucleated cells followed by 54.2, corresponding to cells with pyknotic nuclei, 45.2 of cells with chromatin condensation, 3.7 of cells with broken-egg, 3.6 of cells with micronucleus, and 2.0 of karyolytic cells. Age, worked time, smoking, and alcohol consumption did not have significant influence on nuclear abnormalities in the pilots studied. Pesticide exposure was the main factor for nuclear abnormality results and DNA damage. Marked genotoxic damage was developed even in younger pilots with 2 years of short working period, caused by their daily occupational exposure to pesticides.

Dietary Effects on Cognition and Pilots' Flight Performance.

PubMed

Lindseth, Glenda N; Lindseth, Paul D; Jensen, Warren C; Petros, Thomas V; Helland, Brian D; Fossum, Debra L

2011-01-01

The purpose of this study was to investigate the effects of diet on cognition and flight performance of 45 pilots. Based on a theory of self-care, this clinical study used a repeated-measure, counterbalanced crossover design. Pilots were randomly rotated through 4-day high-carbohydrate, high-protein, high-fat, and control diets. Cognitive flight performance was evaluated using a GAT-2 full-motion flight simulator. The Sternberg short-term memory test and Vandenberg's mental rotation test were used to validate cognitive flight test results. Pilots consuming a high-protein diet had significantly poorer ( p < .05) overall flight performance scores than pilots consuming high-fat and high-carbohydrate diets.

Flight and Ground Instructor Knowledge Test Guide

DOT National Transportation Integrated Search

1994-01-01

The FAA has available hundreds of computer testing centers nationwide. These testing centers offer the full range of airman knowledge tests including military competence, instrument foreign pilot, and pilot examiner screening tests. Refer to appendix...

78 FR 42057 - National Assessment Governing Board; Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-15

... Tasks (ICTs) at grades 4, 8, and 12 for the 2014 pilot test, in preparation for the 2015 NAEP Science assessment; (2) Science Hands-on Tasks (HOTs) at grades 4, 8, and 12 for the 2014 pilot test, in preparation...) Science Interactive Computer Tasks (ICTs) at grades 4, 8, and 12 for the 2014 pilot test, in preparation...

Private and Commercial Pilot: Ligher-Than-Air Airship. Flight Test Guide. (Part 61 Revised).

ERIC Educational Resources Information Center

Federal Aviation Administration (DOT), Washington, DC. Flight Standards Service.

The flight test guide assists the applicant and his instructor in preparing for the flight test for the Private or Commercial Pilot Certificate with a Lighter-Than-Air Category and Airship Class Rating under Part 61 (revised) of Federal Aviation Regulations. It contains information and guidance concerning pilot operations, procedures, and…

Private and Commercial Pilot: Glider. Flight Test Guide, Part 61 Revised, AC 61-61.

ERIC Educational Resources Information Center

Federal Aviation Administration (DOT), Washington, DC. Flight Standards Service.

This flight test guide assists the applicant and his instructor in preparing for the Private or Commercial Pilot Certificate with Glider Rating under Part 61 (revised) of Federal Aviation Regulations. It contains information and guidance concerning the pilot operations, procedures, and maneuvers relevant to the flight test required for that…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grigg, Reid; McPherson, Brian; Lee, Rober

The Southwest Regional Partnership on Carbon Sequestration (SWP) one of seven regional partnerships sponsored by the U.S. Department of Energy (USDOE) carried out five field pilot tests in its Phase II Carbon Sequestration Demonstration effort, to validate the most promising sequestration technologies and infrastructure concepts, including three geologic pilot tests and two terrestrial pilot programs. This field testing demonstrated the efficacy of proposed sequestration technologies to reduce or offset greenhouse gas emissions in the region. Risk mitigation, optimization of monitoring, verification, and accounting (MVA) protocols, and effective outreach and communication were additional critical goals of these field validation tests. Themore » program included geologic pilot tests located in Utah, New Mexico, Texas, and a region-wide terrestrial analysis. Each geologic sequestration test site was intended to include injection of a minimum of ~75,000 tons/year CO{sub 2}, with minimum injection duration of one year. These pilots represent medium- scale validation tests in sinks that host capacity for possible larger-scale sequestration operations in the future. These validation tests also demonstrated a broad variety of carbon sink targets and multiple value-added benefits, including testing of enhanced oil recovery and sequestration, enhanced coalbed methane production and a geologic sequestration test combined with a local terrestrial sequestration pilot. A regional terrestrial sequestration demonstration was also carried out, with a focus on improved terrestrial MVA methods and reporting approaches specific for the Southwest region.« less

Combining destination diversion decisions and critical in-flight event diagnosis in computer aided testing of pilots

NASA Technical Reports Server (NTRS)

Rockwell, T. H.; Giffin, W. C.; Romer, D. J.

1984-01-01

Rockwell and Giffin (1982) and Giffin and Rockwell (1983) have discussed the use of computer aided testing (CAT) in the study of pilot response to critical in-flight events. The present investigation represents an extension of these earlier studies. In testing pilot responses to critical in-flight events, use is made of a Plato-touch CRT system operating on a menu based format. In connection with the typical diagnostic problem, the pilot was presented with symptoms within a flight scenario. In one problem, the pilot has four minutes for obtaining the information which is needed to make a diagnosis of the problem. In the reported research, the attempt has been made to combine both diagnosis and diversion scenario into a single computer aided test. Tests with nine subjects were conducted. The obtained results and their significance are discussed.

The application of the pilot points in groundwater numerical inversion model

NASA Astrophysics Data System (ADS)

Hu, Bin; Teng, Yanguo; Cheng, Lirong

2015-04-01

Numerical inversion simulation of groundwater has been widely applied in groundwater. Compared to traditional forward modeling, inversion model has more space to study. Zones and inversing modeling cell by cell are conventional methods. Pilot points is a method between them. The traditional inverse modeling method often uses software dividing the model into several zones with a few parameters needed to be inversed. However, distribution is usually too simple for modeler and result of simulation deviation. Inverse cell by cell will get the most actual parameter distribution in theory, but it need computational complexity greatly and quantity of survey data for geological statistical simulation areas. Compared to those methods, pilot points distribute a set of points throughout the different model domains for parameter estimation. Property values are assigned to model cells by Kriging to ensure geological units within the parameters of heterogeneity. It will reduce requirements of simulation area geological statistics and offset the gap between above methods. Pilot points can not only save calculation time, increase fitting degree, but also reduce instability of numerical model caused by numbers of parameters and other advantages. In this paper, we use pilot point in a field which structure formation heterogeneity and hydraulics parameter was unknown. We compare inversion modeling results of zones and pilot point methods. With the method of comparative analysis, we explore the characteristic of pilot point in groundwater inversion model. First, modeler generates an initial spatially correlated field given a geostatistical model by the description of the case site with the software named Groundwater Vistas 6. Defining Kriging to obtain the value of the field functions over the model domain on the basis of their values at measurement and pilot point locations (hydraulic conductivity), then we assign pilot points to the interpolated field which have been divided into 4 zones. And add range of disturbance values to inversion targets to calculate the value of hydraulic conductivity. Third, after inversion calculation (PEST), the interpolated field will minimize an objective function measuring the misfit between calculated and measured data. It's an optimization problem to find the optimum value of parameters. After the inversion modeling, the following major conclusion can be found out: (1) In a field structure formation is heterogeneity, the results of pilot point method is more real: better fitting result of parameters, more stable calculation of numerical simulation (stable residual distribution). Compared to zones, it is better of reflecting the heterogeneity of study field. (2) Pilot point method ensures that each parameter is sensitive and not entirely dependent on other parameters. Thus it guarantees the relative independence and authenticity of parameters evaluation results. However, it costs more time to calculate than zones. Key words: groundwater; pilot point; inverse model; heterogeneity; hydraulic conductivity

Electro-Fenton as a feasible advanced treatment process to produce reclaimed water.

PubMed

Durán Moreno, A; Frontana-Uribe, B A; Ramírez Zamora, R M

2004-01-01

The feasibility of the electro-Fenton process to generate simultaneously both of the Fenton's reagent species (Fe2+/H2O2), was assessed as a potentially more economical alternative to the classical Fenton's reaction to produce reclaimed water. An air-saturated combined wastewater (mixture of municipal and laboratory effluents) was treated in discontinuous and continuous reactors at pH = 3.5. The discontinuous reactor was a 2 L electrochemical laboratory cell fitted with concentric graphite and iron electrodes. The continuous reactor tests used a pilot treatment system comprising the aforementioned electrochemical cell, two clarifiers and one sand filter. Several tests were carried out at different conditions of reaction time (0-60 min) and electrical current values (0.2-1.0 A) in the discontinuous reactor. The best operating conditions were 60 min and 1 A without filtration of effluents. At these conditions, in discontinuous and continuous reactors with filtration, the COD, turbidity and color removal were 65-74.8%, 77-92.3% and 80-100%, respectively. Fecal and total coliforms, Escherichia coli, Shigella and Salmonella sp. were not detected at the end of the pilot treatment system. Electrogeneration of the Fenton's reagent is also economical; its cost is one-fifth the cost reported for Advanced Primary Treatment.

Current practices for screening, consent and care of related donors in France: Haematopoietic stem cell transplantation coordinator nurses' perceptions.

PubMed

Polomeni, A; Bompoint, C; Gomez, A; Brissot, E; Ruggeri, A; Belhocine, R; Mohty, M

2017-11-01

Haematopoietic stem cell transplantation-coordinating nurses (HSCT-CNs) play an important role in informing related donors (RDs) and in organising human leucocyte antigen (HLA) tests, pre-donation workup and stem cells collection. Our pilot study aimed to explore French HSCT-CNs' perceptions of RD care issues. Twenty-nine French HSCT adult units were sent a questionnaire on the subject of donation procedures, HSCT-CNs' data and their professional experience of related donation issues. Twenty-two HSCT-CNs returned a completed questionnaire, and 90% of HSCT units were involved to some degree in both patient and donor care. Responses indicated that the provision of information to potential donors prior to HLA tests was insufficient, while donors were given a medical consultation only during the pre-donation workup. Questions were raised about the consent and voluntary status of RDs. None of the HSCT teams organised a post-donation consultation, while 57% provided follow-up by phone or via a questionnaire. Our results draw attention to the conflict of interest experienced by HSCT-CNs when caring simultaneously for patients and donors. The specific psychosocial difficulties associated with becoming an RD are also highlighted. French HSCT-CNs' perceptions of related donation reveal many ethical and clinical problems that have yet to be fully explored. Data on this topic remain scarce, and our pilot study may contribute to the current debate on the organisation of RD care. © 2016 John Wiley & Sons Ltd.

Pilot-scale verification of maximum tolerable hydrodynamic stress for mammalian cell culture.

PubMed

Neunstoecklin, Benjamin; Villiger, Thomas K; Lucas, Eric; Stettler, Matthieu; Broly, Hervé; Morbidelli, Massimo; Soos, Miroslav

2016-04-01

Although several scaling bioreactor models of mammalian cell cultures are suggested and described in the literature, they mostly lack a significant validation at pilot or manufacturing scale. The aim of this study is to validate an oscillating hydrodynamic stress loop system developed earlier by our group for the evaluation of the maximum operating range for stirring, based on a maximum tolerable hydrodynamic stress. A 300-L pilot-scale bioreactor for cultivation of a Sp2/0 cell line was used for this purpose. Prior to cultivations, a stress-sensitive particulate system was applied to determine the stress values generated by stirring and sparging. Pilot-scale data, collected from 7- to 28-Pa maximum stress conditions, were compared with data from classical 3-L cultivations and cultivations from the oscillating stress loop system. Results for the growth behavior, analyzed metabolites, productivity, and product quality showed a dependency on the different environmental stress conditions but not on reactor size. Pilot-scale conditions were very similar to those generated in the oscillating stress loop model confirming its predictive capability, including conditions at the edge of failure.

14 CFR 61.405 - What tests do I have to take to obtain a flight instructor certificate with a sport pilot rating?

Code of Federal Regulations, 2014 CFR

2014-01-01

... flight instructor certificate with a sport pilot rating? 61.405 Section 61.405 Aeronautics and Space..., FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS Flight Instructors With a Sport Pilot Rating § 61.405 What tests do I have to take to obtain a flight instructor certificate with a sport pilot rating? To obtain a...

14 CFR 61.405 - What tests do I have to take to obtain a flight instructor certificate with a sport pilot rating?

Code of Federal Regulations, 2012 CFR

2012-01-01

... flight instructor certificate with a sport pilot rating? 61.405 Section 61.405 Aeronautics and Space..., FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS Flight Instructors With a Sport Pilot Rating § 61.405 What tests do I have to take to obtain a flight instructor certificate with a sport pilot rating? To obtain a...

14 CFR 61.405 - What tests do I have to take to obtain a flight instructor certificate with a sport pilot rating?

Code of Federal Regulations, 2013 CFR

2013-01-01

... flight instructor certificate with a sport pilot rating? 61.405 Section 61.405 Aeronautics and Space..., FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS Flight Instructors With a Sport Pilot Rating § 61.405 What tests do I have to take to obtain a flight instructor certificate with a sport pilot rating? To obtain a...

Evaluation of pilot-scale pulse-corona-induced plasma device to remove NO{sub x} from combustion exhausts from a subscale combustor and from a hush house at Nellis AFB, Nevada. Final report, August 1994--January 1997

DOE Office of Scientific and Technical Information (OSTI.GOV)

Haythornthwaite, S.M.; Durham, M.D.; Anderson, G.L.

1997-05-01

Jet engine test cells (JETCs) are used to test-fire new, installed, and reworked jet engines. Because JETCs have been classified as stationary sources of pollutant emissions, they are subject to possible regulation under Title 1 of the Clean Air Act (CAA) as amended in 1990. In Phase 1 of the Small Business Innovation Research (SBIR) program, a novel NOx-control approach utilizing pulsed-corona-induced plasma successfully showed 90% removal of NOx in the laboratory. The objective of Phase 2 was to reproduce the laboratory-scale results in a pilot-scale system. The technology was successfully demonstrated at pilot scale in the field, on amore » slipstream of JETC flue gas at Nellis Air Force Base. Based on the field data, cost projections were made for a system to treat the full JETC exhaust. The technology efficiently converted NO into ONO, and a wet scrubber was required to achieve the treatment goal of 50-percent removal and destruction of NOx. The plasma simultaneously removes hydrocarbons from the flue gas stream. This project demonstrated that pulse-corona-induced plasma technology is scalable to practical industrial dimensions.« less

Applying image quality in cell phone cameras: lens distortion

NASA Astrophysics Data System (ADS)

Baxter, Donald; Goma, Sergio R.; Aleksic, Milivoje

2009-01-01

This paper describes the framework used in one of the pilot studies run under the I3A CPIQ initiative to quantify overall image quality in cell-phone cameras. The framework is based on a multivariate formalism which tries to predict overall image quality from individual image quality attributes and was validated in a CPIQ pilot program. The pilot study focuses on image quality distortions introduced in the optical path of a cell-phone camera, which may or may not be corrected in the image processing path. The assumption is that the captured image used is JPEG compressed and the cellphone camera is set to 'auto' mode. As the used framework requires that the individual attributes to be relatively perceptually orthogonal, in the pilot study, the attributes used are lens geometric distortion (LGD) and lateral chromatic aberrations (LCA). The goal of this paper is to present the framework of this pilot project starting with the definition of the individual attributes, up to their quantification in JNDs of quality, a requirement of the multivariate formalism, therefore both objective and subjective evaluations were used. A major distinction in the objective part from the 'DSC imaging world' is that the LCA/LGD distortions found in cell-phone cameras, rarely exhibit radial behavior, therefore a radial mapping/modeling cannot be used in this case.

Flight-test experience in digital control of a remotely piloted vehicle.

NASA Technical Reports Server (NTRS)

Edwards, J. W.

1972-01-01

The development of a remotely piloted vehicle system consisting of a remote pilot cockpit and a ground-based digital computer coupled to the aircraft through telemetry data links is described. The feedback control laws are implemented in a FORTRAN program. Flight-test experience involving high feedback gain limits for attitude and attitude rate feedback variables, filtering of sampled data, and system operation during intermittent telemetry data link loss is discussed. Comparisons of closed-loop flight tests with analytical calculations, and pilot comments on system operation are included.

Pilot production of 4 sq cm ITO/InP photovoltaic solar cells

NASA Technical Reports Server (NTRS)

Gessert, T. A.; Li, X.; Coutts, T. J.; Tzafaras, N.

1991-01-01

Experimental results of a pilot production of 32 4-sq cm indium tin oxide (ITO)InP space solar cells are presented. The discussion includes analysis of the device performance of the best cells produced as well as the performance range of all production cells. The experience gained from the production is discussed, indicating other issues that may be encountered when large-scale productions are initiated. Available data on a 4-sq cm ITO/InP cell that was flown on the UoSAT-5 satellite is reported.

F-18 HARV research pilot Dana Purifoy

NASA Technical Reports Server (NTRS)

1996-01-01

Dana D. Purifoy is an aerospace research pilot at NASA's Dryden Flight Research Center, Edwards, California. He joined NASA in August 1994. Purifoy is a former Air Force test pilot who served as a project pilot in the joint NASA/Air Force X-29 Forward Swept Wing research program conducted at Dryden from 1984 to 1991. His most recent assignment in the Air Force was flying U-2 aircraft as a test pilot at Air Force Plant 42, Palmdale, CA. In addition to flying the X-29 at Dryden as an Air Force pilot, Purifoy also served as project pilot and joint test force director with the AFTI F-16 (Advanced Fighter Technology Integration/F-16) program, also located at Dryden. Before his assignments as project pilot on the X-29 and AFTI/F-16 aircraft, Purifoy was chief of the Academics Systems Branch at the Air Force Test Pilot School at Edwards. Prior to becoming a test pilot, he flew F-111 and F-16 aircraft in Great Britain and Germany. He has accumulated 3800 hours of flying time in his career. The final flight for the F-18 High Alpha Research Vehicle (HARV) took place at NASA Dryden on May 29, 1996. The highly modified F-18 airplane flew 383 flights over a nine year period and demonstrated concepts that greatly increase fighter maneuverability. Among concepts proven in the aircraft is the use of paddles to direct jet engine exhaust in cases of extreme altitudes where conventional control surfaces lose effectiveness. Another concept, developed by NASA Langley Research Center, is a deployable wing-like surface installed on the nose of the aircraft for increased right and left (yaw) control on nose-high flight angles.

Electrokinetically Emplaced Amendments for Enhanced Bioremediation of Chlorinated Solvents in Clay: a Pilot Field Test

NASA Astrophysics Data System (ADS)

O'Carroll, D. M.; Inglis, A.; Head, N.; Chowdhury, A. I.; Garcia, A. N.; Reynolds, D. A.; Hogberg, D.; Edwards, E.; Lomheim, L.; Austrins, L. M.; Hayman, J.; Auger, M.; Sidebottom, A.; Eimers, J.; Gerhard, J.

2017-12-01

Bioremediation is an increasingly popular treatment technology for contaminated sites due to the proven success of biostimulation and bioaugmentation. However, bioremediation, along with other in-situ remediation technologies, faces limitations due to challenges with amendment delivery in low permeability media. Studies have suggested that electrokinetics (EK) can enhance the delivery of amendments in low permeability soils, such as clay. A pilot field trial was conducted to evaluate the potential for electrokinetics to support anaerobic dechlorination in clay by improving the transport of lactate and microorganisms. The study was performed on a former chlorinated solvent production facility in Ontario, Canada. Five transect cells were set up within the contaminated clay test area. Different amendments were injected in three of these cells to test various remediation strategies under the influence of EK. The other two cells were used as controls, one with EK applied and the other with no EK. This study focuses on the cell that applied electrokinetics for lactate emplacement followed by bioremediation (EK-Bio). This cell had an initial single injection of KB-1 bioaugmentation culture (SiREM, Canada) followed by injection of sodium lactate as a biostimulant while direct current was applied for 45 days between two electrodes 3 m apart. EK can enhance lactate migration by electromigration, while microorganisms have the potential to be influenced by electroosmosis of the bulk fluid or by electrophoresis of the charged bacteria themselves. All monitoring well locations in the EK-Bio cell exhibited evidence of successful lactate delivery corresponding to an increase in dissolved organic carbon. Reduction in chlorinated volatile organic compound (cVOC) concentrations, in particular 1,2-dichloroethane (1,2-DCA), were evident in monitoring locations coinciding with significant lactate breakthrough. Further investigation into the influence of EK-Bio on the abundance and distribution of microbial communities is being explored using soil and groundwater samples collected throughout the duration of the field trial. This study provides original insights into the application of electrokinetically-enhanced bioremediation as a treatment strategy for contaminated, low permeability porous media.

Research, development and pilot production of high output thin silicon solar cells

NASA Technical Reports Server (NTRS)

Iles, P. A.

1976-01-01

Work was performed to define and apply processes which could lead to high output from thin (2-8 mils) silicon solar cells. The overall problems are outlined, and two satisfactory process sequences were developed. These sequences led to good output cells in the thickness range to just below 4 mils; although the initial contract scope was reduced, one of these sequences proved capable of operating beyond a pilot line level, to yield good quality 4-6 mil cells of high output.

A flight test method for pilot/aircraft analysis

NASA Technical Reports Server (NTRS)

Koehler, R.; Buchacker, E.

1986-01-01

In high precision flight maneuvres a pilot is a part of a closed loop pilot/aircraft system. The assessment of the flying qualities is highly dependent on the closed loop characteristics related to precision maneuvres like approach, landing, air-to-air tracking, air-to-ground tracking, close formation flying and air-to air refueling of the receiver. The object of a research program at DFVLR is the final flight phase of an air to ground mission. In this flight phase the pilot has to align the aircraft with the target, correct small deviations from the target direction and keep the target in his sights for a specific time period. To investigate the dynamic behavior of the pilot-aircraft system a special ground attack flight test technique with a prolonged tracking maneuvres was developed. By changing the targets during the attack the pilot is forced to react continously on aiming errors in his sights. Thus the closed loop pilot/aircraft system is excited over a wide frequency range of interest, the pilot gets more information about mission oriented aircraft dynamics and suitable flight test data for a pilot/aircraft analysis can be generated.

The Effect of Ownship Information and NexRad Resolution on Pilot Decision Making in the Use of a Cockpit Weather Information Display

NASA Technical Reports Server (NTRS)

Novacek, Paul F.; Burgess, Malcolm A.; Heck, Michael L.; Stokes, Alan F.; Stough, H. Paul, III (Technical Monitor)

2001-01-01

A two-phase experiment was conducted to explore the effects of data-link weather displays upon pilot decision performance. The experiment was conducted with 49 instrument rated pilots who were divided into four groups and placed in a simulator with a realistic flight scenario involving weather containing convective activity. The inflight weather display depicted NEXRAD images, with graphical and textual METARs over a moving map display. The experiment explored the effect of weather information, ownship position symbology and NEXRAD cell size resolution. The phase-two experiment compared two groups using the data-linked weather display with ownship position symbology. These groups were compared to the phase-one group that did not have ownship position symbology. The phase-two pilots were presented with either large NEXRAD cell size (8 km) or small cell size (4 km). Observations noted that the introduction of ownship symbology did not appear to significantly impact the decision making process, however, the introduction of ownship did reduce workload. Additionally, NEXRAD cell size resolution did appear to influence the tactical decision making process.

Milk Enhancements Improve Milk Consumption and Increase Meal Participation in the NSLP: The School Milk Pilot Test

ERIC Educational Resources Information Center

Rafferty, Karen; Zipay, Diane; Patey, Camellia; Meyer, Jennifer

2009-01-01

Purpose/Objectives: The objective of the School Milk Pilot Test and the Westside School Milk Pilot Study was to test the effect of a milk enhancement initiative to make milk more appealing and attractive to elementary and secondary school students and to improve milk consumption. Methods: 146 schools participated in the national School Milk Pilot…

A Preliminary Investigation into Cognitive Aptitudes Predictive of Overall MQ-1 Predator Pilot Qualification Training Performance

DTIC Science & Technology

2015-11-06

Predator pilot vacancies. The purpose of this study was to evaluate computer-based intelligence and neuropsychological testing on training...high-risk, high-demand occupation. 15. SUBJECT TERMS Remotely piloted aircraft, RPA, neuropsychological screening, intelligence testing , computer...based testing , Predator, MQ-1 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT SAR 18. NUMBER OF PAGES 20 19a. NAME OF

Helicopter flight investigation to determine the effects of a closed-circuit TV on performance of a precision sling-load handling task

NASA Technical Reports Server (NTRS)

Dicarlo, D. J.; Kelley, H. L.; Spivey, D. L.

1974-01-01

Helicopter sling-load operations have been limited during hover and low-speed flight by the degree of precision achieved by the pilot/helicopter/sling-load combination. Previous attempts to improve precision have included stabilization of the load and helicopter and the addition of a pilot station directly facing the load. In these tests, use of a closed-circuit TV as a display that would permit sling-load delivery and placement by the forward-facing pilot was evaluated using a CH-54B helicopter. In all, three test cases were documented, which included the following: (1) forward-facing pilot using the TV display, (2) forward-facing pilot using verbal commands from a load-facing observer, and (3) aft-facing pilot using direct visual cues. The results indicate that a comparable level of performance was achieved for each test case; however, an increase in pilot workload was noted when the TV system was used.

The Effects of Longitudinal Control-System Dynamics on Pilot Opinion and Response Characteristics as Determined from Flight Tests and from Ground Simulator Studies

NASA Technical Reports Server (NTRS)

Sadoff, Melvin

1958-01-01

The results of a fixed-base simulator study of the effects of variable longitudinal control-system dynamics on pilot opinion are presented and compared with flight-test data. The control-system variables considered in this investigation included stick force per g, time constant, and dead-band, or stabilizer breakout force. In general, the fairly good correlation between flight and simulator results for two pilots demonstrates the validity of fixed-base simulator studies which are designed to complement and supplement flight studies and serve as a guide in control-system preliminary design. However, in the investigation of certain problem areas (e.g., sensitive control-system configurations associated with pilot- induced oscillations in flight), fixed-base simulator results did not predict the occurrence of an instability, although the pilots noted the system was extremely sensitive and unsatisfactory. If it is desired to predict pilot-induced-oscillation tendencies, tests in moving-base simulators may be required. It was found possible to represent the human pilot by a linear pilot analog for the tracking task assumed in the present study. The criterion used to adjust the pilot analog was the root-mean-square tracking error of one of the human pilots on the fixed-base simulator. Matching the tracking error of the pilot analog to that of the human pilot gave an approximation to the variation of human-pilot behavior over a range of control-system dynamics. Results of the pilot-analog study indicated that both for optimized control-system dynamics (for poor airplane dynamics) and for a region of good airplane dynamics, the pilot response characteristics are approximately the same.

External quality assurance of HER2 fluorescence in situ hybridisation testing: results of a UK NEQAS pilot scheme.

PubMed

Bartlett, John M S; Ibrahim, Merdol; Jasani, Bharat; Morgan, John M; Ellis, Ian; Kay, Elaine; Magee, Hilary; Barnett, Sarah; Miller, Keith

2007-07-01

Trastuzumab provides clinical benefit for advanced and early breast cancer patients whose tumours over-express or have gene amplification of the HER2 oncogene. The UK National External Quality Assessment Scheme (NEQAS) for immunohistochemical testing was established to assess and improve the quality of HER2 immunohistochemical testing. However, until recently, no provision was available for HER2 fluorescence in situ hybridisation (FISH) testing. A pilot scheme was set up to review the performance of FISH testing in clinical diagnostic laboratories. FISH was performed in 6 reference and 31 participating laboratories using a cell line panel with known HER2 status. Using results from reference laboratories as a criterion for acceptable performance, 60% of all results returned by participants were appropriate and 78% either appropriate or acceptable. However, 22.4% of results returned were deemed inappropriate, including 13 cases (4.2%) where a misdiagnosis would have been made had these been clinical specimens. The results of three consecutive runs show that both reference laboratories and a proportion of routine clinical diagnostic (about 25%) centres can consistently achieve acceptable quality control of HER2 testing. Data from a significant proportion of participating laboratories show that further steps are required, including those taken via review of performance under schemes such as NEQAS, to improve quality of HER2 testing by FISH in the "real world".

F-18 chase craft with NASA test pilots Schneider and Fulton

NASA Technical Reports Server (NTRS)

1992-01-01

Ed Schneider, (left), is the project pilot for the F-18 High Angle of Attack program at NASA's Dryden Flight Research Center, Edwards, California. He has been a NASA research pilot at Dryden since 1983. In addition to his assignment with the F-18 High Angle of Attack program, Schneider is a project pilot for the F-15B aeronautical research aircraft, the NASA NB-52B launch aircraft, and the SR-71 'Blackbird' aircraft. He is a Fellow and was the 1994 President of the Society of Experimental Test Pilots. In 1996 he was awarded the NASA Exceptional Service Medal. Schneider is seen here with Fitzhugh L. Fulton Jr., (right), who was a civilian research pilot at Dryden. from August 1, 1966, until July 3, 1986, following 23 years of service as a pilot in the U.S. Air Force. Fulton was the project pilot on all early tests of the 747 Shuttle Carrier Aircraft (SCA) used to air launch the Space Shuttle prototype Enterprise in the Approach and Landing Tests (ALT) at Dryden in l977. For his work in the ALT program, Fulton received NASA's Exceptional Service Medal. He also received the Exceptional Service Medal again in 1983 for flying the 747 SCA during the European tour of the Space Shuttle Enterprise. During his career at Dryden, Fulton was project pilot on NASA's NB-52B launch aircraft used to air launch a variety of piloted and unpiloted research aircraft, including the X-15s and lifting bodies. He flew the XB-70 prototype supersonic bomber on both NASA-USAF tests and NASA research flights during the late 1960s, attaining speeds exceeding Mach 3. He was also a project pilot on the YF-12A and YF-12C research program from April 14, 1969, until September 25, 1978. The F/A-18 Hornet seen behind them is used primarily as a safety chase and support aircraft at NASA's Dryden Flight Research Center, Edwards, Calif. As support aircraft, the F-18's are used for safety chase, pilot proficiency and aerial photography. As a safety chase aircraft, F-18's, flown by research pilots, accompany research missions as another 'set of eyes' to visually observe the research event, experiment or test to help make sure the flights are carried out safely. The 'chase' pilots are in constant communication with the research pilots and mission control to report abnormalities that may be seen from the support aircraft. Pilots must also stay proficient by flying a certain number of missions per month. F-18's are used for this. A two-seat support aircraft is also used when research missions require an engineer or photographer on the flights.

The effectiveness of airline pilot training for abnormal events.

PubMed

Casner, Stephen M; Geven, Richard W; Williams, Kent T

2013-06-01

To evaluate the effectiveness of airline pilot training for abnormal in-flight events. Numerous accident reports describe situations in which pilots responded to abnormal events in ways that were different from what they had practiced many times before. One explanation for these missteps is that training and testing for these skills have become a highly predictable routine for pilots who arrive to the training environment well aware of what to expect. Under these circumstances, pilots get plentiful practice in responding to abnormal events but may get little practice in recognizing them and deciding which responses to offer. We presented 18 airline pilots with three abnormal events that are required during periodic training and testing. Pilots were presented with each event under the familiar circumstances used during training and also under less predictable circumstances as they might occur during flight. When presented in the routine ways seen during training, pilots gave appropriate responses and showed little variability. However, when the abnormal events were presented unexpectedly, pilots' responses were less appropriate and showed great variability from pilot to pilot. The results suggest that the training and testing practices used in airline training may result in rote-memorized skills that are specific to the training situation and that offer modest generalizability to other situations. We recommend a more complete treatment of abnormal events that allows pilots to practice recognizing the event and choosing and recalling the appropriate response. The results will aid the improvement of existing airline training practices.

DEVELOPMENT, TESTING, AND DEMONSTRATION OF AN OPTIMAL FINE COAL CLEANING CIRCUIT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Steven R. Hadley; R. Mike Mishra; Michael Placha

1999-01-27

The objective of this project was to improve the efficiency of the fine coal froth flotation circuit in commercial coal preparation plants. The plant selected for this project, Cyprus Emerald Coal Preparation Plant, cleans 1200-1400 tph of Pittsburgh seam raw coal and uses conventional flotation cells to clean the minus 100-mesh size fraction. The amount of coal in this size fraction is approximately 80 tph with an average ash content of 35%. The project was carried out in two phases. In Phase I, four advanced flotation cells, i.e., a Jameson cell, an Outokumpu HG tank cell, an open column, andmore » a packed column cell, were subjected to bench-scale testing and demonstration. In Phase II, two of these flotation cells, the Jameson cell and the packed column, were subjected to in-plant, proof-of-concept (POC) pilot plant testing both individually and in two-stage combination in order to ascertain whether a two-stage circuit results in lower levelized production costs. The bench-scale results indicated that the Jameson cell and packed column cell would be amenable to the single- and two-stage flotation approach. POC tests using these cells determined that single-stage coal matter recovery (CMR) of 85% was possible with a product ash content of 5.5-7%. Two-stage operation resulted in a coal recovery of 90% with a clean coal ash content of 6-7.5%. This compares favorably with the plant flotation circuit recovery of 80% at a clean coal ash of 11%.« less

Piloted Simulation Tests of Propulsion Control as Backup to Loss of Primary Flight Controls for a B747-400 Jet Transport

DOT National Transportation Integrated Search

1997-04-01

This report describes the concept of a propulsion controlled aircraft (PCA), : discusses pilot controls, displays, and procedures; and presents the results of a : PCA piloted simulation test and evaluation of the B747-400 airplane conducted at : NASA...

77 FR 56866 - Agency Information Collection Activities: Proposed Collection; Comment Request, Generic Clearance...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-14

... Collection Activities: Proposed Collection; Comment Request, Generic Clearance for Cognitive, Pilot and Field... information collection clearance that will allow BJS to conduct a variety of cognitive, pilot, and field test... new or modified data collection, BJS will engage in cognitive, pilot and field test activities to...

77 FR 69658 - Agency Information Collection Activities; Proposed Collection; Comment Request: Generic Clearance...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-20

... Activities; Proposed Collection; Comment Request: Generic Clearance for Cognitive, Pilot and Field Studies...) Title of the Form/Collection: BJS Generic Clearance for Cognitive, Pilot, and Field Test Studies. (3... respondents will be involved in exploratory, field test, pilot, cognitive, and focus group work conducted...

77 FR 56867 - Agency Information Collection Activities: Proposed Collection; Comment Request; Generic Clearance...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-14

... Collection Activities: Proposed Collection; Comment Request; Generic Clearance for Cognitive, Pilot and Field... information collection clearance that will allow BJS to conduct a variety of cognitive, pilot, and field test... new or modified data collection, BJS will engage in cognitive, pilot and field test activities to...

The Effects of System and Environmental Factors Upon Experienced Pilot Performance in the Advanced Simulator for Pilot Training

DTIC Science & Technology

1977-04-01

System by System Variable Interactions Across All Maneuvers ... .......... 23 11 Field of View by Motion Interaction Cell Means for Takeoff...23 12 Motion by Field :f View Interaction Cell Means for GCA ..... ................. 24 13 Motion by FOV Interaction Mc--n Ratings for the...GCA and Takeoff Maneuvers ... ....... 24 14 Motion by G.Seat Interaction Cell Means for Takeoff ...... ................... 25 15 Motion by G.Seat

Manual flying of curved precision approaches to landing with electromechanical instrumentation. A piloted simulation study

NASA Technical Reports Server (NTRS)

Knox, Charles E.

1993-01-01

A piloted simulation study was conducted to examine the requirements for using electromechanical flight instrumentation to provide situation information and flight guidance for manually controlled flight along curved precision approach paths to a landing. Six pilots were used as test subjects. The data from these tests indicated that flight director guidance is required for the manually controlled flight of a jet transport airplane on curved approach paths. Acceptable path tracking performance was attained with each of the three situation information algorithms tested. Approach paths with both multiple sequential turns and short final path segments were evaluated. Pilot comments indicated that all the approach paths tested could be used in normal airline operations.

A pilot study of an autologous tumor-derived autophagosome vaccine with docetaxel in patients with stage IV non-small cell lung cancer.

PubMed

Sanborn, Rachel E; Ross, Helen J; Aung, Sandra; Acheson, Anupama; Moudgil, Tarsem; Puri, Sachin; Hilton, Traci; Fisher, Brenda; Coffey, Todd; Paustian, Christopher; Neuberger, Michael; Walker, Edwin; Hu, Hong-Ming; Urba, Walter J; Fox, Bernard A

2017-12-19

Tumor-derived autophagosome vaccines (DRibbles) have the potential to broaden immune response to poorly immunogenic tumors. Autologous vaccine generated from tumor cells harvested from pleural effusions was administered to patients with advanced NSCLC with the objectives of assessing safety and immune response. Four patients were vaccinated and evaluable for immune response; each received two to four doses of vaccine. Study therapy included two cycles of docetaxel 75 mg/m 2 on days 1 and 29 to treat the tumor, release hidden antigens and produce lymphopenia. DRibbles were to be administered intradermally on days 14, 43, 57, 71, and 85, together with GM-CSF (50 μg/d x 6d, administered via SQ mini pump). Peripheral blood was tested for immune parameters at baseline and at each vaccination. Three of four patients had tumor cells available for testing. Autologous tumor-specific immune response was seen in two of the three, manifested by IL-5 (1 patient after 3 doses), and IFN-γ, TNF-α, IL-5, IL-10 (after 4 doses in one patient). All 4 patients had evidence of specific antibody responses against potential tumor antigens. All patients came off study after 4 or fewer vaccine treatments due to progression of disease. No significant immune toxicities were seen during the course of the study. DRibble vaccine given with GM-CSF appeared safe and capable of inducing an immune response against tumor cells in this small, pilot study. There was no evidence of efficacy in this small poor-prognosis patient population, with treatment not feasible. Trial registration NCT00850785, initial registration date February 23, 2009.

How Well do the Military Services Perform Jointly in Combat? DoD’s Joint Test-and-Evaluation Program Provides Few Credible Answers.

DTIC Science & Technology

1984-02-22

of the test conditions were unrealistic. For example, four better-than-average pilots flew all the test missions in mostly excellent weather, in one...that aircraft pilots need to respond to a request for close air support is likely to influence combat effectiveness. Earl- ier joint testing had made...in the JTF reports. For example, the IIR Maverick report contains the conclusion that, in general, the pilots detected targets easily, but the test

Lumbar spine intervertebral disc gene delivery: a pilot study in lewis rats.

PubMed

Damle, Sheela R; Rawlins, Bernard A; Boachie-Adjei, Oheneba; Crystal, Ronald G; Hidaka, Chisa; Cunningham, Matthew E

2013-02-01

Basic research toward understanding and treating disc pathology in the spine has utilized numerous animal models, with delivery of small molecules, purified factors, and genes of interest. To date, gene delivery to the rat lumbar spine has only been described utilizing genetically programmed cells in a matrix which has required partial disc excision, and expected limitation of treatment diffusion into the disc. This study was designed to develop and describe a surgical technique for lumbar spine exposure and disc space preparation, and use of a matrix-free method for gene delivery. Naïve or genetically programmed isogeneic bone marrow stromal cells were surgically delivered to adolescent male Lewis rat lumbar discs, and utilizing quantitative biochemical and qualitative immunohistological assessments, the implanted cells were detected 3 days post-procedure. Statistically significant differences were noted for recovery of the β-galactosidase marker gene comparing delivery of naïve or labeled cells (10(5) cells per disc) from the site of implantation, and between delivery of 10(5) or 10(6) labeled cells per disc at the site of implantation and the adjacent vertebral body. Immunohistology confirmed that the β-galactosidase marker was detected in the adjacent vertebra bone in the zone of surgical implantation. The model requires further testing in larger cohorts and with biologically active genes of interest, but the observations from the pilot experiments are very encouraging that this will be a useful comparative model for basic spine research involving gene or cell delivery, or other locally delivered therapies to the intervertebral disc or adjacent vertebral bodies in rats.

Computer-aided testing of pilot response to critical in-flight events

NASA Technical Reports Server (NTRS)

Giffin, W. C.; Rockwell, T. H.

1984-01-01

This research on pilot response to critical in-flight events employs a unique methodology including an interactive computer-aided scenario-testing system. Navigation displays, instrument-panel displays, and assorted textual material are presented on a touch-sensitive CRT screen. Problem diagnosis scenarios, destination-diversion scenarios and combined destination/diagnostic tests are available. A complete time history of all data inquiries and responses is maintained. Sample results of diagnosis scenarios obtained from testing 38 licensed pilots are presented and discussed.

Recreational Pilot and Private Pilot Knowledge Test Guide

DOT National Transportation Integrated Search

1995-01-01

The Flight Standards Service of the Federal Aviation Administration (FAA) has developed this guide to help : applicants meet the knowledge requirements for recreational pilot and private pilot certification. : This guide contains information about el...

Pilot Scale Production and Testing of a Recombinant Staphylococcal Enterotoxin (SEB) Triple Mutant

DTIC Science & Technology

2017-09-01

1 PILOT-SCALE PRODUCTION AND TESTING OF A RECOMBINANT STAPHYLOCOCCAL ENTEROTOXIN (SEB) TRIPLE MUTANT ECBC...Disclaimer The findings in this report are not to be construed as an official Department of the Army position unless so designated by other authorizing...TYPE Final 3. DATES COVERED (From - To) Mar 2010 – Dec 2011 4. TITLE AND SUBTITLE Pilot-Scale Production and Testing of a Recombinant

14 CFR 61.405 - What tests do I have to take to obtain a flight instructor certificate with a sport pilot rating?

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false What tests do I have to take to obtain a flight instructor certificate with a sport pilot rating? 61.405 Section 61.405 Aeronautics and Space... flight instructor certificate with a sport pilot rating you must pass the following tests: (a) Knowledge...

14 CFR 61.405 - What tests do I have to take to obtain a flight instructor certificate with a sport pilot rating?

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false What tests do I have to take to obtain a flight instructor certificate with a sport pilot rating? 61.405 Section 61.405 Aeronautics and Space... flight instructor certificate with a sport pilot rating you must pass the following tests: (a) Knowledge...

An Examination of the Perceived Importance of Technical Competence in Acquisition Project Management

DTIC Science & Technology

1991-09-01

Develop (First Draft) Instructions Critique (Revision) Answerability Pilot Test (Second Draft) Analysis Response Mode Revision Useability Preparation...appropriate questionnaire items. Initially, the set of questions developed for the study reflected a few shortcomings. A pilot test of the first draft among...resulted. First, feedback from the pilot test indicated a need to reduce the completion time. Because the multiple choice format required several

Pilot Jerrie Cobb Trains in the Multi-Axis Space Test Inertia Facility

NASA Image and Video Library

1960-04-21

Jerrie Cobb prepares to operate the Multi-Axis Space Test Inertia Facility (MASTIF) inside the Altitude Wind Tunnel at the National Aeronautics and Space Administration (NASA) Lewis Research Center. The MASTIF was a three-axis rig with a pilot’s chair mounted in the center to train Project Mercury pilots to bring a spinning spacecraft under control. An astronaut was secured in a foam couch in the center of the rig. The rig was then spun on three axes from 2 to 50 rotations per minute. The pilots were tested on each of the three axis individually, then all three simultaneously. The two controllers in Cobb’s hands activated the small nitrogen gas thrusters that were used to bring the MASTIF under control. A makeshift spacecraft control panel was set up in front of the trainee’s face. Cobb was one of several female pilots who underwent the skill and endurance testing that paralleled that of the Project Mercury astronauts. In 1961 Jerrie Cobb was the first female to pass all three phases of the Mercury Astronaut Program. NASA rules, however, stipulated that only military test pilots could become astronauts and there were no female military test pilots. The seven Mercury astronauts had taken their turns on the MASTIF in February and March 1960.

Subsonic stability and control derivatives for an unpowered, remotely piloted 3/8-scale F-15 airplane model obtained from flight test

NASA Technical Reports Server (NTRS)

Iliff, K. W.; Maine, R. E.; Shafer, M. F.

1976-01-01

In response to the interest in airplane configuration characteristics at high angles of attack, an unpowered remotely piloted 3/8-scale F-15 airplane model was flight tested. The subsonic stability and control characteristics of this airplane model over an angle of attack range of -20 to 53 deg are documented. The remotely piloted technique for obtaining flight test data was found to provide adequate stability and control derivatives. The remotely piloted technique provided an opportunity to test the aircraft mathematical model in an angle of attack regime not previously examined in flight test. The variation of most of the derivative estimates with angle of attack was found to be consistent, particularly when the data were supplemented by uncertainty levels.

Histomorphometric Analysis of Angiogenesis using CD31 Immunomarker and Mast Cell Density in Oral Premalignant and Malignant Lesions: A Pilot Study.

PubMed

Jyothsna, M; Rammanohar, M; Kumar, Kiran

2017-01-01

Mast cells have been implicated in promoting angiogenesis in malignant tumors of lung, oesophagus and breast, but there are few studies on Oral Squamous Cell Carcinomas (OSCC). Most oral squamous cell carcinomas arise from pre-existing precancerous lesions exhibiting epithelial dysplasia. The present pilot study attempts to compare Mast Cell Density (MCD), Microvessel Density (MVD), Microvessel Area (MVA) histomorphometrically between normal buccal mucosa, severe epithelial dysplasia and OSCC and to correlate the role of mast cells and angiogenesis in tumor progression. The retrospective study was conducted on eight cases of OSCC, eight cases of severe epithelial dysplasia and five cases of normal buccal mucosa. Immunohistochemical staining with anti CD-31, to demonstrate angiogenesis and toluidine blue staining for mast cells were employed. MVA, MVD and MCD were calculated using the measurement tools of the image analysis software and compared between the groups. One way ANOVA (Analysis of Variance) was used for comparing the parameter for multiple groups followed by Games Howell test. To assess the relationship between micro vessel density and mast cell density, Karl Pearson's correlation was used. MCD and MVD increased with disease progression and were statistically higher in OSCC than in severe epithelial dysplasia and normal buccal mucosa (p<0.001). MVA increased from normal to severe dysplasia and decreased from dysplasia to OSCC, may be due to revascularization of tumor tissue. A positive correlation was observed between MCD and MVD in OSCC and dysplasia, though were not statistically significant. These findings suggest that mast cells may up regulate angiogenesis in OSCC. MCD and MVD may be used as indicators for disease progression.

Pilot testing a predoctoral dental public health curriculum: reporting process and outcomes.

PubMed

Bhoopathi, Vinodh; Atchison, Kathryn Ann

2015-01-01

The purpose of this study was to pilot test the predoctoral dental public health (DPH) curriculum developed by the American Association of Public Health Dentistry (AAPHD) in various US dental schools and dental hygiene programs. Following the Lewy's theoretical framework, we used all three curriculum tryout methods (laboratory tryout, pilot tryout, and field tryout) for the pilot testing process. Open-ended questions on the structure, presentation, and content of the curriculum were sent to faculty pilot testing the DPH curriculum to obtain critical feedback and comments. Between Summer 2013 and Spring 2015, the curriculum was pilot tested in nine dental schools and seven dental hygiene programs with over 1,300 students. The majority of the comments from the faculty were favorable. Positive comments about the structure of the curriculum focused on the well-organized nature of the curriculum, the value of the instructor guide and speaker notes, rubrics, and the flow of the presentations. In terms of the content, faculty commented on the wide range of public health issues covered and the clarity of course and lecture objectives. Negative comments dealt with the level of detail, some confusing assignments, and outdated data. Problems identified in pilot testing were corrected in the final DPH curriculum. The curriculum was successfully utilized in varied formats and well received. Through AAPHD, this standardized DPH core curriculum is now available for widespread use at dental schools and dental hygiene programs. © 2015 American Association of Public Health Dentistry.

An investigation into pilot and system response to critical in-flight events, volume 2

NASA Technical Reports Server (NTRS)

Rockwell, T. H.; Giffin, W. C.

1981-01-01

Critical in-flight event is studied using mission simulation and written tests of pilot responses. Materials and procedures used in knowledge tests, written tests, and mission simulations are included

77 FR 56865 - Agency Information Collection Activities: Proposed Collection; Comment Request; Generic Clearance...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-14

... Collection Activities: Proposed Collection; Comment Request; Generic Clearance for Cognitive, Pilot and Field... information collection clearance that will allow BJS to conduct a variety of cognitive, pilot, and field test... each new or modified data collection, BJS will engage in cognitive, pilot and field test activities to...

Engineering sciences area and module performance and failure analysis area

NASA Technical Reports Server (NTRS)

Ross, R. G., Jr.; Runkle, L. D.

1982-01-01

Photovoltaic-array/power-conditioner interface studies are updated. An experiment conducted to evaluate different operating-point strategies, such as constant voltage and pilot cells, and to determine array energy losses when the array is operated off the maximum power points is described. Initial results over a test period of three and a half weeks showed a 2% energy loss when the array is operated at a fixed voltage. Degraded-array studies conducted at NE RES that used a range of simulated common types of degraded I-V curves are reviewed. The instrumentation installed at the JPL field-test site to obtain the irradiance data was described. Experiments using an optical filter to adjust the spectral irradiance of the large-area pulsed solar simulator (LAPSS) to AM1.5 are described. Residential-array research activity is reviewed. Voltage isolation test results are described. Experiments performed on one type of module to determine the relationship between leakage current and temperature are reviewed. An encapsulated-cell testing approach is explained. The test program, data reduction methods, and initial results of long-duration module testing are described.

Evaluation of a pilot-scale sewage biogas powered 2.8 kWe Solid Oxide Fuel Cell: Assessment of heat-to-power ratio and influence of oxygen content

NASA Astrophysics Data System (ADS)

de Arespacochaga, N.; Valderrama, C.; Peregrina, C.; Mesa, C.; Bouchy, L.; Cortina, J. L.

2015-12-01

Biogas from anaerobic digestion of organic matter is a promising renewable energy source and fuel cells appear as a breakthrough technology to improve the performance of the biogas-to-energy valorisation chain. The vast majority of studies addressing biogas energy recovery through Solid Oxide Fuel Cells published in recent years correspond to simulations and lab-scale performance with synthetic biogas. This paper assesses the pilot performance of a 2.8 kWe SOFC unit powered with cleaned sewage biogas for around 700 h in a Wastewater Treatment Plant. The biogas thorough treatment consisting of a biological desulphurisation with a biotrickling filter followed by a deep cleaning step based on adsorption is successful for removing sulphur compounds, siloxanes and hydrocarbons. The influence of the heat-to-power ratio on fuel cell performance is investigated operating the system at O/C ratio of 2, reforming temperature of 550 °C, stack temperature of 800 °C and at a constant voltage of 43 V. At optimized conditions for electrical production satisfying heat demand in the WWTP, system electrical and thermal efficiencies account for 34% and 28%. Cogeneration efficiency remains constant at around 59-62% for all the heat-to-power ratios tested. Furthermore, the impact of the oxygen content in the biogas is also studied.

Field Testing of a Wet FGD Additive for Enhanced Mercury Control - Pilot-Scale Test Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gary M. Blythe

2006-03-01

This Topical Report summarizes progress on Cooperative Agreement DE-FC26-04NT42309, ''Field Testing of a Wet FGD Additive.'' The objective of the project is to demonstrate the use of a flue gas desulfurization (FGD) additive, Degussa Corporation's TMT-15, to prevent the reemissions of elemental mercury (Hg{sup 0}) in flue gas exiting wet FGD systems on coal-fired boilers. Furthermore, the project intends to demonstrate that the additive can be used to precipitate most of the mercury (Hg) removed in the wet FGD system as a fine TMT salt that can be separated from the FGD liquor and bulk solid byproducts for separate disposal.more » The project will conduct pilot and full-scale tests of the TMT-15 additive in wet FGD absorbers. The tests are intended to determine required additive dosage requirements to prevent Hg{sup 0} reemissions and to separate mercury from the normal FGD byproducts for three coal types: Texas lignite/Power River Basin (PRB) coal blend, high-sulfur Eastern bituminous coal, and low-sulfur Eastern bituminous coal. The project team consists of URS Group, Inc., EPRI, TXU Generation Company LP, Southern Company, and Degussa Corporation. TXU Generation has provided the Texas lignite/PRB co-fired test site for pilot FGD tests, Monticello Steam Electric Station Unit 3. Southern Company is providing the low-sulfur Eastern bituminous coal host site for wet scrubbing tests, as well as the pilot and full-scale jet bubbling reactor (JBR) FGD systems to be tested. A third utility, to be named later, will provide the high-sulfur Eastern bituminous coal full-scale FGD test site. Degussa Corporation is providing the TMT-15 additive and technical support to the test program. The project is being conducted in six tasks. Of the six project tasks, Task 1 involves project planning and Task 6 involves management and reporting. The other four tasks involve field testing on FGD systems, either at pilot or full scale. The four tasks include: Task 2 - Pilot Additive Testing in Texas Lignite Flue Gas; Task 3 - Full-scale FGD Additive Testing in High Sulfur Eastern Bituminous Flue Gas; Task 4 - Pilot Wet Scrubber Additive Tests at Yates; and Task 5 - Full-scale Additive Tests at Plant Yates. This topical report presents the results from the Task 2 and Task 4 pilot-scale additive tests. The Task 3 and Task 5 full-scale additive tests will be conducted later in calendar year 2006.« less

Safety and Immunogenicity Testing of a Pilot Polysaccharide Vaccine Preparation to Pseudomonas aeruginosa.

DTIC Science & Technology

1981-09-01

8217-NAL." BUR-._,AL)- ’..O,.-,.S.AN--DA. .-D-S.... . . . .A AD___________ Safety and Immunogenicity Testing of a Pilot Polysaccharide Vaccine Preparation...COVERED Safety and Immunogenicity Testing of a Pilot Annual Report Polysaccharide Vaccine Preparation to (16 Aug. 80 - 1 Aug. 81) Pseudomonas...immunogenic or biologically active component of the vaccine. The vaccine is a high molecu- lar weight polysaccharide (PS) material isolated from the outer

Nicotine deprivation and pilot performance during simulated flight.

PubMed

Mumenthaler, Martin S; Benowitz, Neal L; Taylor, Joy L; Friedman, Leah; Noda, Art; Yesavage, Jerome A

2010-07-01

Most airlines enforce no-smoking policies, potentially causing flight performance decrements in pilots who are smokers. We tested the hypotheses that nicotine withdrawal affects aircraft pilot performance within 12 h of smoking cessation and that chewing nicotine gum leads to significant relief of these withdrawal effects. There were 29 pilots, regular smokers, who were tested in a Frasca 141 flight simulator on two 13-h test days, each including three 75-min flights (0 hr, 6 hr, 12 hr) in a randomized, controlled trial. On the first day (baseline), all pilots smoked one cigarette per hour. On the second day, pilots were randomly assigned to one of four groups: (1) nicotine cigarettes; (2) nicotine gum; (3) placebo gum; (4) no cigarettes/no gum. Flight Summary Scores (FSS) were compared between groups with repeated measures ANOVAs. No statistically significant differences in overall simulator flight performance were revealed between pilots who smoked cigarettes and pilots who were not allowed to smoke cigarettes or chew nicotine gum, but there was a trend for pilots who were not allowed to smoke to perform worse. However, pilots who chewed placebo gum performed significantly worse during the 6-h (FSS = -0.03) as well as during the 12-h flight (FSS = -0.08) than pilots who chewed nicotine gum (FSS = 0.15 / 0.30, respectively). Results suggest that nicotine withdrawal effects can impair aircraft pilot performance within 12 h of smoking cessation and that during smoking abstinence chewing one stick of 4-mg nicotine gum per hour may lead to significantly better overall flight performance compared to chewing placebo gum.

Pilot-scale production of fuel ethanol from concentrated food waste hydrolysates using Saccharomyces cerevisiae H058.

PubMed

Yan, Shoubao; Chen, Xiangsong; Wu, Jingyong; Wang, Pingchao

2013-07-01

The aim of this study was to develop a bioprocess to produce ethanol from food waste at laboratory, semipilot and pilot scales. Laboratory tests demonstrated that ethanol fermentation with reducing sugar concentration of 200 g/L, inoculum size of 2 % (Initial cell number was 2 × 10⁶ CFU/mL) and addition of YEP (3 g/L of yeast extract and 5 g/L of peptone) was the best choice. The maximum ethanol concentration in laboratory scale (93.86 ± 1.15 g/L) was in satisfactory with semipilot scale (93.79 ± 1.11 g/L), but lower than that (96.46 ± 1.12 g/L) of pilot-scale. Similar ethanol yield and volumetric ethanol productivity of 0.47 ± 0.02 g/g, 1.56 ± 0.03 g/L/h and 0.47 ± 0.03 g/g, 1.56 ± 0.03 g/L/h after 60 h of fermentation in laboratory and semipilot fermentors, respectively, however, both were lower than that (0.48 ± 0.02 g/g, 1.79 ± 0.03 g/L/h) of pilot reactor. In addition, simple models were developed to predict the fermentation kinetics during the scale-up process and they were successfully applied to simulate experimental results.

Analysis of responses of cold pressor tests on pilots and executives

NASA Technical Reports Server (NTRS)

Swaroop, R.

1977-01-01

Statistical analyses were performed to study the relationship between cold pressor test responses and certain medical attributes of a group of 81 pilots and a group of 466 executives. The important results of this study were as follows: There was a significant relationship between a subject's cold pressor test response and his profession (that is, pilot or executive). The executives' diastolic cold pressor test responses were significantly related to their medical conditions, and their families' medical conditions. Significant relationships were observed between executives' diastolic and systolic cold pressor test responses and their history of tranquilizer and cardiac drug use.

23 years of toxicology testing fatally injured pilots: Implications for aviation and other modes of transportation.

PubMed

McKay, Mary Pat; Groff, Loren

2016-05-01

Use of over-the-counter, prescription, and illicit drugs is increasing in the United States (US). Many of these drugs are psychoactive and can affect the user's ability to safely operate a vehicle. However, data about drug use by vehicle operators is typically limited to a small proportion of operators and a short list of drugs. For instance, required testing for commercial vehicle operators following most accidents is limited to a urine test for 11 drugs. By comparison, the Federal Aviation Administration (FAA), routinely tests fatally injured pilots' blood and tissues for hundreds of compounds. This study used the results from these tests to assess drug use in aviation. Using matched data from the FAA's Civil Aerospace Medical Institute toxicology database and the National Transportation Safety Board's (NTSB's) aviation accident database, this study examined trends in the prevalence of over-the-counter, prescription, and illicit drugs identified in toxicology tests of fatally injured pilots between 1990 and 2012. Cases that failed to match or where toxicology testing had not been performed were excluded. Pilots identified by the NTSB investigation as being the "flying pilot" at the time of the accident and results from blood or tissues were included. Toxicology results for ethanol and other alcohols were not included. Positive test results were categorized by drug type and potential for causing impairment. Analysis used SPSS Version 19.1 to perform linear by linear chi-squared statistics. The study included 6677 pilots or 87% of the eligible subjects. The large majority were male (98%) and flying general aviation operations (96%) at the time of their fatal accident. There were increasing trends in pilots' use of all drugs, potentially impairing drugs, drugs used to treat potentially impairing conditions, drugs designated as controlled substances, and illicit drugs. The most common potentially impairing drug pilots had used was diphenhydramine, a sedating antihistamine that is an active ingredient in many over-the-counter allergy formulations, cold medicines, and sleep aids in the US. Although evidence of illicit drug use was found only in a small number of cases, the percentage of pilots testing positive for marijuana use increased during the study period, mostly in the last 10 years. Published by Elsevier Ltd.

EVALUATION OF FGD DRY INJECTION SORBENTS AND ADDITIVES - VOLUME 2 - PILOT PLANT EVALUATION OF HIGH REACTIVITY SORBENTS

EPA Science Inventory

The report describes a mini-pilot test program to investigate potential new sorbents and processes for dry SO2 removal. Initial tests showed that the 85 cu m/h pilot plant could be used successfully to evaluate both spray dryer and dry injection processes using traditional calciu...

Carbon Mineralization by Aqueous Precipitation for Beneficial Use of CO2 from Flue Gas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Devenney, Martin; Gilliam, Ryan; Seeker, Randy

2013-08-01

The objective of this project is to demonstrate an innovative process to mineralize CO2 from flue gas directly to reactive carbonates and maximize the value and versatility of its beneficial use products. The program scope includes the design, construction, and testing of a CO2 Conversion to Material Products (CCMP) Pilot Demonstration Plant utilizing CO2 from the flue gas of a power production facility in Moss Landing, CA. This topical report covers Subphase 2a which is the design phase of pilot demonstration subsystems. Materials of construction have been selected and proven in both lab scale and prototype testing to be acceptablemore » for the reagent conditions of interest. The target application for the reactive carbonate material has been selected based upon small-scale feasibility studies and the design of a continuous fiber board production line has been completed. The electrochemical cell architecture and components have been selected based upon both lab scale and prototype testing. The appropriate quality control and diagnostic techniques have been developed and tested along with the required instrumentation and controls. Finally the demonstrate site infrastructure, NEPA categorical exclusion, and permitting is all ready for the construction and installation of the new units and upgrades.« less

Seat cushion to provide realistic acceleration cues to aircraft simulator pilot

NASA Technical Reports Server (NTRS)

Ashworth, B. R. (Inventor)

1979-01-01

Seat cushions, each including an air cell with a non-compressible surface, are disclosed. The apparatus are provided for initially controlling the air pressure in the air cells to allow the two main support areas of the simulator pilot to touch the non-compressible surface and thus begin to compress the flesh near these areas. During a simulated flight the apparatus control the air pressure in the cells to simulate the events that occur in a seat cushion during actual flight.

Flight performance using a hyperstereo helmet-mounted display: aircraft handling

NASA Astrophysics Data System (ADS)

Jennings, Sion A.; Craig, Gregory L.; Stuart, Geoffrey W.; Kalich, Melvyn E.; Rash, Clarence E.; Harding, Thomas H.

2009-05-01

A flight study was conducted to assess the impact of hyperstereopsis on helicopter handling proficiency, workload and pilot acceptance. Three pilots with varying levels of night vision goggle and hyperstereo helmet-mounted display experience participated in the test. The pilots carried out a series of flights consisting of low-level maneuvers over a period of two weeks. Four of the test maneuvers, The turn around the tail, the hard surface landing, the hover height estimation and the tree-line following were analysed in detail. At the end of the testing period, no significant difference was observed in the performance data, between maneuvers performed with the TopOwl helmet and maneuvers performed with the standard night vision goggle. This study addressed only the image intensification display aspects of the TopOwl helmet system. The tests did not assess the added benefits of overlaid symbology or head slaved infrared camera imagery. These capabilities need to be taken into account when assessing the overall usefulness of the TopOwl system. Even so, this test showed that pilots can utilize the image intensification imagery displayed on the TopOwl to perform benign night flying tasks to an equivalent level as pilots using ANVIS. The study should be extended to investigate more dynamic and aggressive low level flying, slope landings and ship deck landings. While there may be concerns regarding the effect of hyperstereopsis on piloting, this initial study suggests that pilots can either adapt or compensate for hyperstereo effects with sufficient exposure and training. Further analysis and testing is required to determine the extent of training required.

Piloted simulation tests of propulsion control as backup to loss of primary flight controls for a mid-size jet transport

NASA Technical Reports Server (NTRS)

Bull, John; Mah, Robert; Davis, Gloria; Conley, Joe; Hardy, Gordon; Gibson, Jim; Blake, Matthew; Bryant, Don; Williams, Diane

1995-01-01

Failures of aircraft primary flight-control systems to aircraft during flight have led to catastrophic accidents with subsequent loss of lives (e.g. , DC-1O crash, B-747 crash, C-5 crash, B-52 crash, and others). Dryden Flight Research Center (DFRC) investigated the use of engine thrust for emergency flight control of several airplanes, including the B-720, Lear 24, F-15, C-402, and B-747. A series of three piloted simulation tests have been conducted at Ames Research Center to investigate propulsion control for safely landing a medium size jet transport which has experienced a total primary flight-control failure. The first series of tests was completed in July 1992 and defined the best interface for the pilot commands to drive the engines. The second series of tests was completed in August 1994 and investigated propulsion controlled aircraft (PCA) display requirements and various command modes. The third series of tests was completed in May 1995 and investigated PCA full-flight envelope capabilities. This report describes the concept of a PCA, discusses pilot controls, displays, and procedures; and presents the results of piloted simulation evaluations of the concept by a cross-section of air transport pilots.

Food, forest wastes = low Btu fuel

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goss, J.R.

1978-01-01

Development of an experimental gasifier at the Univ. of California at Davis is reviewed. The unit produces 6 to 8 million Btu/h by converting mulled walnut shells into a combustible gas. Experience gained in the project can be applied to other gasification projects. Three additional tests are planned for the pilot plant using densified rice hulls to supply heat for rice drying; using screened, densified gin trash to supply heat for a cotton gin; and using sawmill residues, primarily bark, to replace the natural gas fuel used in a dry kiln. After completion of these trials, further trials may includemore » burning cereal straw to power a diesel-electric generator for an irrigation project; burning timber harvesting residues to run a small municipal power plant; and supplying energy to operate a fuel cell pilot plant.« less

Vessel-associated stem cells from skeletal muscle: From biology to future uses in cell therapy.

PubMed

Sancricca, Cristina; Mirabella, Massimiliano; Gliubizzi, Carla; Broccolini, Aldobrando; Gidaro, Teresa; Morosetti, Roberta

2010-06-26

Over the last years, the existence of different stem cells with myogenic potential has been widely investigated. Besides the classical skeletal muscle progenitors represented by satellite cells, numerous multipotent and embryologically unrelated progenitors with a potential role in muscle differentiation and repair have been identified. In order to conceive a therapeutic approach for degenerative muscle disorders, it is of primary importance to identify an ideal stem cell endowed with all the features for a possible use in vivo. Among all emerging populations, vessel-associated stem cells are a novel and promising class of multipotent progenitors of mesodermal origin and with high myogenic potential which seem to best fit all the requirements for a possible cell therapy. In vitro and in vivostudies have already tested the effectiveness and safety of vessel-associated stem cells in animal models. This leads to the concrete possibility in the future to start pilot human clinical trials, hopefully opening the way to a turning point in the treatment of genetic and acquired muscle disorders.

IARC - Illinois Accelerator Research Center | Pilot Program

Science.gov Websites

Toggle navigation Pilot Program Agenda Directions Registration Illinois Accelerator Research Center National Laboratory present Accelerator Stewardship Test Facility Pilot Program Use accelerator technology , energy and environment. With this pilot program, the DOE Office of Science National Laboratories are

Flight test experience and controlled impact of a large, four-engine, remotely piloted airplane

NASA Technical Reports Server (NTRS)

Kempel, R. W.; Horton, T. W.

1985-01-01

A controlled impact demonstration (CID) program using a large, four engine, remotely piloted transport airplane was conducted. Closed loop primary flight control was performed from a ground based cockpit and digital computer in conjunction with an up/down telemetry link. Uplink commands were received aboard the airplane and transferred through uplink interface systems to a highly modified Bendix PB-20D autopilot. Both proportional and discrete commands were generated by the ground pilot. Prior to flight tests, extensive simulation was conducted during the development of ground based digital control laws. The control laws included primary control, secondary control, and racetrack and final approach guidance. Extensive ground checks were performed on all remotely piloted systems. However, manned flight tests were the primary method of verification and validation of control law concepts developed from simulation. The design, development, and flight testing of control laws and the systems required to accomplish the remotely piloted mission are discussed.

Image analysis supported moss cell disruption in photo-bioreactors.

PubMed

Lucumi, A; Posten, C; Pons, M-N

2005-05-01

Diverse methods for the disruption of cell entanglements and pellets of the moss Physcomitrella patens were tested in order to improve the homogeneity of suspension cultures. The morphological characterization of the moss was carried out by means of image analysis. Selected morphological parameters were defined and compared to the reduction of the carbon dioxide fixation, and the released pigments after cell disruption. The size control of the moss entanglements based on the rotor stator principle allowed a focused shear stress, avoiding a severe reduction in the photosynthesis. Batch cultures of P. patens in a 30.0-l pilot tubular photo-bioreactor with cell disruption showed no significant variation in growth rate and a delayed cell differentiation, when compared to undisrupted cultures. A highly controlled photoautotrophic culture of P. patens in a scalable photo-bioreactor was established, contributing to the development required for the future use of mosses as producers of relevant heterologous proteins.

Training General Aviation Pilots for Convective Weather Situations.

PubMed

Blickensderfer, Elizabeth L; Lanicci, John M; Vincent, Michael J; Thomas, Robert L; Smith, MaryJo; Cruit, Jessica K

2015-10-01

Over the past 10-15 yr, considerable research has occurred for the development, testing, and fielding of real-time Datalink weather products for general aviation (GA) pilots to use before and during flight. As is the case with the implementation of most new technologies, work is needed to ensure that the users (in this case, the pilots) understand both the capabilities and limitations of the new technologies as well as how to use the new systems to improve their task performance. The purpose of this study was to replicate and extend a previous study on training pilots how and when to use these new weather technologies. This field study used a quasi-experimental design (pre- vs. post-test with a control group). There were 91 GA pilots from the Midwest, Northeastern, and Southeastern United States who participated in a 2-h short course or a control activity. The lecture-based short course covered radar basics, Next Generation Weather Radar (NEXRAD), NEXRAD specifics/limitations, thunderstorm basics, radar products, and decision making. The pilots who participated in the course earned higher knowledge test scores, improved at applying the concepts in paper-based flight scenarios, had higher self-efficacy in post-training assessments as compared to pre-training assessments, and also performed better than did control subjects on post-test knowledge and skills assessments. GA pilots lack knowledge about real-time Datalink weather technology. This study indicates that a relatively short training program was effective for fostering Datalink weather-related knowledge and skills in GA pilots.

General Aviation Flight Test of Advanced Operations Enabled by Synthetic Vision

NASA Technical Reports Server (NTRS)

Glaab, Louis J.; Hughhes, Monica F.; Parrish, Russell V.; Takallu, Mohammad A.

2014-01-01

A flight test was performed to compare the use of three advanced primary flight and navigation display concepts to a baseline, round-dial concept to assess the potential for advanced operations. The displays were evaluated during visual and instrument approach procedures including an advanced instrument approach resembling a visual airport traffic pattern. Nineteen pilots from three pilot groups, reflecting the diverse piloting skills of the General Aviation pilot population, served as evaluation subjects. The experiment had two thrusts: 1) an examination of the capabilities of low-time (i.e., <400 hours), non-instrument-rated pilots to perform nominal instrument approaches, and 2) an exploration of potential advanced Visual Meteorological Conditions (VMC)-like approaches in Instrument Meteorological Conditions (IMC). Within this context, advanced display concepts are considered to include integrated navigation and primary flight displays with either aircraft attitude flight directors or Highway In The Sky (HITS) guidance with and without a synthetic depiction of the external visuals (i.e., synthetic vision). Relative to the first thrust, the results indicate that using an advanced display concept, as tested herein, low-time, non-instrument-rated pilots can exhibit flight-technical performance, subjective workload and situation awareness ratings as good as or better than high-time Instrument Flight Rules (IFR)-rated pilots using Baseline Round Dials for a nominal IMC approach. For the second thrust, the results indicate advanced VMC-like approaches are feasible in IMC, for all pilot groups tested for only the Synthetic Vision System (SVS) advanced display concept.

Centrifuge-induced neck and back pain in F-16 pilots: a report of four cases.

PubMed

Lange, Britt; Nielsen, René Tyranski; Skejø, Pernille Bro; Toft, Palle

2013-07-01

Early in their careers, as an important part of their training to become fighter pilots, pilots undergo centrifuge training in order to learn effective anti-G straining maneuvers (AGSM) and to test their G tolerance. The exposure of pilots, especially early in their careers, to training that could lead to injuries should be avoided. This is a report of four cases of neck pain experienced during G-tolerance training, some of which may have caused ongoing problems for the pilot. Four cases, describing four different injuries experienced during G-tolerance training, are presented, including the history of the incident, radiographic description, and physical examination. Three main questions were identified in regards to the training of fighter pilots in centrifuges: 1) should the seat be positioned to imitate a specific aircraft's seat? 2) should the pilot wear a helmet and a mask? 3) what is the appropriate amount of head support? Based on the four cases reported it is recommended that pilots should be given the best possible conditions concerning neck support and load on the neck and the back for G-tolerance testing. Training the pilot in an anatomical neutral sitting position, without a helmet, and with maximal neck support minimizes head movements in cases of conscious or unconscious loss of muscle control. To test the stability of the neck in a setup similar to the environment where the pilot is going to operate, the pilot should be given the opportunity to prepare himself or herself accordingly in advance.

Results of a simulator test comparing two display concepts for piloted flight-path-angle control

NASA Technical Reports Server (NTRS)

Kelley, W. W.

1978-01-01

Results of a simulator experiment which was conducted in order to compare pilot gamma-control performance using two display formats are reported. Pilots flew a variable flight path angle tracking task in the landing configuration. Pilot and airplane performance parameters were recorded and pilot comments noted for each case.

Individual Learning Account Pilot Initiative: A Learning Tool for the 21st Century. Report to the OPM Director.

ERIC Educational Resources Information Center

President's Task Force on Federal Training Technology, Washington, DC.

The U.S. Office of Personnel Management (OPM) evaluated the feasibility of individual learning accounts (ILAs) as an approach to workforce development. Thirteen federal agencies volunteered to participate in the initiative. Together, they conducted a total of 17 pilot tests. Some pilot tests included all employees in the agency. Others targeted…

An Evaluation of the Head Start Bilingual Bicultural Curriculum Development Project. Pilot Study Results and Child Assessment Measures.

ERIC Educational Resources Information Center

Chesterfield, Ray; And Others

The purpose of this part of the multimethod Head Start bilingual/bicultural curriculum evaluation (Juarez and Associates, 1979), is to present the results of a pilot test of a battery of instruments to be used in assessing the effectiveness of four early childhood bilingual/bicultural curriculum models. The instruments pilot tested were the…

Space shuttle pilot-induced-oscillation research testing

NASA Technical Reports Server (NTRS)

Powers, B. G.

1984-01-01

The simulation requirements for investigation of pilot-induced-oscillation (PIO) characteristics during the landing phase are discussed. Orbiters simulations and F-8 digital fly-by-wire aircraft tests are addressed.

Dietary Effects on Cognition and Pilots’ Flight Performance

PubMed Central

Lindseth, Glenda N.; Lindseth, Paul D.; Jensen, Warren C.; Petros, Thomas V.; Helland, Brian D.; Fossum, Debra L.

2017-01-01

The purpose of this study was to investigate the effects of diet on cognition and flight performance of 45 pilots. Based on a theory of self-care, this clinical study used a repeated-measure, counterbalanced crossover design. Pilots were randomly rotated through 4-day high-carbohydrate, high-protein, high-fat, and control diets. Cognitive flight performance was evaluated using a GAT-2 full-motion flight simulator. The Sternberg short-term memory test and Vandenberg’s mental rotation test were used to validate cognitive flight test results. Pilots consuming a high-protein diet had significantly poorer (p < .05) overall flight performance scores than pilots consuming high-fat and high-carbohydrate diets. PMID:29353985

External quality assurance of HER2 fluorescence in situ hybridisation testing: results of a UK NEQAS pilot scheme

PubMed Central

Bartlett, John M S; Ibrahim, Merdol; Jasani, Bharat; Morgan, John M; Ellis, Ian; Kay, Elaine; Magee, Hilary; Barnett, Sarah; Miller, Keith

2007-01-01

Background and Aims Trastuzumab provides clinical benefit for advanced and early breast cancer patients whose tumours over‐express or have gene amplification of the HER2 oncogene. The UK National External Quality Assessment Scheme (NEQAS) for immunohistochemical testing was established to assess and improve the quality of HER2 immunohistochemical testing. However, until recently, no provision was available for HER2 fluorescence in situ hybridisation (FISH) testing. A pilot scheme was set up to review the performance of FISH testing in clinical diagnostic laboratories. Methods FISH was performed in 6 reference and 31 participating laboratories using a cell line panel with known HER2 status. Results Using results from reference laboratories as a criterion for acceptable performance, 60% of all results returned by participants were appropriate and 78% either appropriate or acceptable. However, 22.4% of results returned were deemed inappropriate, including 13 cases (4.2%) where a misdiagnosis would have been made had these been clinical specimens. Conclusions The results of three consecutive runs show that both reference laboratories and a proportion of routine clinical diagnostic (about 25%) centres can consistently achieve acceptable quality control of HER2 testing. Data from a significant proportion of participating laboratories show that further steps are required, including those taken via review of performance under schemes such as NEQAS, to improve quality of HER2 testing by FISH in the “real world”. PMID:16963466

Transitioning the GED[R] Mathematics Test to Computer with and without Accommodations: A Pilot Project

ERIC Educational Resources Information Center

Patterson, Margaret Becker; Higgins, Jennifer; Bozman, Martha; Katz, Michael

2011-01-01

We conducted a pilot study to see how the GED Mathematics Test could be administered on computer with embedded accessibility tools. We examined test scores and test-taker experience. Nineteen GED test centers across five states and 216 randomly assigned GED Tests candidates participated in the project. GED candidates completed two GED mathematics…

Effective Training for Flight in Icing Conditions

NASA Technical Reports Server (NTRS)

Barnhart, Billy P.; Ratvasky, Thomas P.

2007-01-01

The development of a piloted flight simulator called the Ice Contamination Effects Flight Training Device (ICEFTD) was recently completed. This device demonstrates the ability to accurately represent an iced airplane s flight characteristics and is utilized to train pilots in recognizing and recovering from aircraft handling anomalies that result from airframe ice formations. The ICEFTD was demonstrated at three recent short courses hosted by the University of Tennessee Space Institute. It was also demonstrated to a group of pilots at the National Test Pilot School. In total, eighty-four pilots and flight test engineers from industry and the regulatory community spent approximately one hour each in the ICEFTD to get a "hands on" lesson of an iced airplane s reduced performance and handling qualities. Additionally, pilot cues of impending upsets and recovery techniques were demonstrated. The purpose of this training was to help pilots understand how ice contamination affects aircraft handling so they may apply that knowledge to the operations of other aircraft undergoing testing and development. Participant feedback on the ICEFTD was very positive. Pilots stated that the simulation was very valuable, applicable to their occupations, and provided a safe way to explore the flight envelope. Feedback collected at each demonstration was also helpful to define additional improvements to the ICEFTD; many of which were then implemented in subsequent demonstrations.

Demonstration of an Ice Contamination Effects Flight Training Device

NASA Technical Reports Server (NTRS)

Ratvasky, Thomas P.; Ranaudo, Richard J.; Blankenship, Kurt S.; Lee, Sam

2006-01-01

The development of a piloted flight simulator called the Ice Contamination Effects Flight Training Device (ICEFTD) was recently completed. This device demonstrates the ability to accurately represent an iced airplane s flight characteristics and is utilized to train pilots in recognizing and recovering from aircraft handling anomalies that result from airframe ice formations. The ICEFTD was demonstrated at three recent short courses hosted by the University of Tennessee Space Institute. It was also demonstrated to a group of pilots at the National Test Pilot School. In total, eighty-four pilots and flight test engineers from industry and the regulatory community spent approximately one hour each in the ICEFTD to get a "hands on" lesson of an iced airplane s reduced performance and handling qualities. Additionally, pilot cues of impending upsets and recovery techniques were demonstrated. The purpose of this training was to help pilots understand how ice contamination affects aircraft handling so they may apply that knowledge to the operations of other aircraft undergoing testing and development. Participant feedback on the ICEFTD was very positive. Pilots stated that the simulation was very valuable, applicable to their occupations, and provided a safe way to explore the flight envelope. Feedback collected at each demonstration was also helpful to define additional improvements to the ICEFTD; many of which were then implemented in subsequent demonstrations

Remotely Piloted Aircraft for Research

NASA Technical Reports Server (NTRS)

Rezek, T. W.

1985-01-01

NASA Technical Memorandum presents overview of remotely-piloted research vehicle (RPRV) activities. Controlled from ground, vehicles allow new concepts tried without subjecting pilots to danger. Critical role of pilot in flight testing with RPRV's demonstrated repeatedly, and many system anomalies uncovered with no risk to human life.

UTILIZATION OF TREATABILITY AND PILOT TESTS TO PREDICT CAH BIOREMEDIATION

EPA Science Inventory

Multiple tools have been suggested to help in the design of enhanced anaerobic bioremediation systems for CAHs:
- Extensive high quality microcosm testing followed by small-scale, thoroughly observed field pilot tests (i.e., RABITT Protocol, Morse 1998)
- More limited ...

78 FR 59706 - Proposed Collection; 30-Day Comment Request; Evaluation of a Kidney Disease Education and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-27

... deliver education to the client and administer the client pre-test/post-test surveys. The pilot study will... pre-test/post-test surveys to assess: (a) Knowledge gains about kidney disease, (b) awareness of NKDEP... respondent burden (hours) hours Pilot study collection: Promotores Promotores training pre-test, post- 12 1 5...

NASA Pilot and Researcher Prepare for a Solar Cell Calibration Flight

NASA Image and Video Library

1964-04-21

Pilot Earle Boyer and researcher Henry Brandhorst prepare for a solar cell calibration flight in a Martin B-57B Canberra at the National Aeronautics and Space Administration (NASA) Lewis Research Center. Lewis was in the early stages of decades-long energy conversion and space power research effort. Brandhorst, a member of the Chemistry and Energy Conversion Division, led a team of Lewis researchers in a quest to develop new power sources to sustain spacecraft in orbit. Solar cells proved to be an important source of energy, but researchers discovered that their behavior varied at different atmospheric levels. Their standardization and calibration were critical. Brandhorst initiated a standardized way to calibrate solar cells in the early 1960s using the B-57B aircraft. The pilots would take the aircraft up into the troposphere and open the solar cell to the sunlight. The aircraft would steadily descend while instruments recorded how much energy was being captured by the solar cell. From this data, Brandhorst could determine the estimated power for a particular solar cell at any altitude. Pilot Earle Boyer joined NASA Lewis in October 1962. He had flown Convair F-102 Delta Dagger fighters in the Air Force and served briefly in the National Guard before joining the Langley Research Center. Boyer was only at Langley a few months before he transferred to Cleveland. He flew the B-57B, a Convair F-106 Delta Dart, Gulfstream G-1 with an experimental turboprop, Learjet and many other aircraft over the next 32 years at Lewis.

Simulation Test Of Descent Advisor

NASA Technical Reports Server (NTRS)

Davis, Thomas J.; Green, Steven M.

1991-01-01

Report describes piloted-simulation test of Descent Advisor (DA), subsystem of larger automation system being developed to assist human air-traffic controllers and pilots. Focuses on results of piloted simulation, in which airline crews executed controller-issued descent advisories along standard curved-path arrival routes. Crews able to achieve arrival-time precision of plus or minus 20 seconds at metering fix. Analysis of errors generated in turns resulted in further enhancements of algorithm to increase accuracies of its predicted trajectories. Evaluations by pilots indicate general support for DA concept and provide specific recommendations for improvement.

Ultra scale-down device to predict dewatering levels of solids recovered in a continuous scroll decanter centrifuge.

PubMed

Lopes, A G; Keshavarz-Moore, E

2013-01-01

During centrifugation operation, the major challenge in the recovery of extracellular proteins is the removal of the maximum liquid entrapped within the spaces between the settled solids-dewatering level. The ability of the scroll decanter centrifuge (SDC) to process continuously large amounts of feed material with high concentration of solids without the need for resuspension of feeds, and also to achieve relatively high dewatering, could be of great benefit for future use in the biopharmaceutical industry. However, for reliable prediction of dewatering in such a centrifuge, tests using the same kind of equipment at pilot-scale are required, which are time consuming and costly. To alleviate the need of pilot-scale trials, a novel USD device, with reduced amounts of feed (2 mL) and to be used in the laboratory, was developed to predict the dewatering levels of a SDC. To verify USD device, dewatering levels achieved were plotted against equivalent compression (Gtcomp ) and decanting (Gtdec ) times, obtained from scroll rates and feed flow rates operated at pilot-scale, respectively. The USD device was able to successfully match dewatering trends of the pilot-scale as a function of both Gtcomp and Gtdec , particularly for high cell density feeds, hence accounting for all key variables that influenced dewatering in a SDC. In addition, it accurately mimicked the maximum dewatering performance of the pilot-scale equipment. Therefore the USD device has the potential to be a useful tool at early stages of process development to gather performance data in the laboratory thus minimizing lengthy and costly runs with pilot-scale SDC. © 2013 American Institute of Chemical Engineers.

Aboveground Injection Sytem Construction and Mecahnical Integrity Test Plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Jun

An In-Situ Bioremediation (ISB) Pilot Test Treatability Study is planned at Sandia National Laboratories, New Mexico (SNL/NM) Technical Area-V (TA-V) Groundwater Area of Concern. The Treatability Study is designed to gravity inject an electron-donor substrate and bioaugmentation bacteria into groundwater using an injection well. The constituents of concern (COCs) are nitrate and trichloroethene (TCE). The Pilot Test Treatability Study will evaluate the effectiveness of bioremediation and COC treatment over a prescribed period of time. Results of the pilot test will provide data that will be used to evaluate the cost and effectiveness of a fullscale system.

Measurement of human pilot dynamic characteristics in flight simulation

NASA Technical Reports Server (NTRS)

Reedy, James T.

1987-01-01

Fast Fourier Transform (FFT) and Least Square Error (LSE) estimation techniques were applied to the problem of identifying pilot-vehicle dynamic characteristics in flight simulation. A brief investigation of the effects of noise, input bandwidth and system delay upon the FFT and LSE techniques was undertaken using synthetic data. Data from a piloted simulation conducted at NASA Ames Research Center was then analyzed. The simulation was performed in the NASA Ames Research Center Variable Stability CH-47B helicopter operating in fixed-basis simulator mode. The piloting task consisted of maintaining the simulated vehicle over a moving hover pad whose motion was described by a random-appearing sum of sinusoids. The two test subjects used a head-down, color cathode ray tube (CRT) display for guidance and control information. Test configurations differed in the number of axes being controlled by the pilot (longitudinal only versus longitudinal and lateral), and in the presence or absence of an important display indicator called an 'acceleration ball'. A number of different pilot-vehicle transfer functions were measured, and where appropriate, qualitatively compared with theoretical pilot- vehicle models. Some indirect evidence suggesting pursuit behavior on the part of the test subjects is discussed.

Adapting the Critical Thinking Assessment Test for Palestinian Universities

ERIC Educational Resources Information Center

Basha, Sami; Drane, Denise; Light, Gregory

2016-01-01

Critical thinking is a key learning outcome for Palestinian students. However, there are no validated critical thinking tests in Arabic. Suitability of the US developed Critical Thinking Assessment Test (CAT) for use in Palestine was assessed. The test was piloted with university students in English (n = 30) and 4 questions were piloted in Arabic…

Mathematics Placement Test: Typical Results with Unexpected Outcomes

ERIC Educational Resources Information Center

Ingalls, Victoria

2011-01-01

Based on the results of a prior case-study analysis of mathematics placement at one university, the mathematics department developed and piloted a mathematics placement test. This article describes the implementation process for a mathematics placement test and further analyzes the test results for the pilot group. As an unexpected result, the…

14 CFR 135.301 - Crewmember: Tests and checks, grace provisions, training to accepted standards.

Code of Federal Regulations, 2014 CFR

2014-01-01

... PERSONS ON BOARD SUCH AIRCRAFT Crewmember Testing Requirements § 135.301 Crewmember: Tests and checks... a flight check under this part, completes the test or flight check in the calendar month before or... pilot serve, as a flight crewmember in operations under this part until the pilot has satisfactorily...

14 CFR 135.301 - Crewmember: Tests and checks, grace provisions, training to accepted standards.

Code of Federal Regulations, 2013 CFR

2013-01-01

... PERSONS ON BOARD SUCH AIRCRAFT Crewmember Testing Requirements § 135.301 Crewmember: Tests and checks... a flight check under this part, completes the test or flight check in the calendar month before or... pilot serve, as a flight crewmember in operations under this part until the pilot has satisfactorily...

14 CFR 135.301 - Crewmember: Tests and checks, grace provisions, training to accepted standards.

Code of Federal Regulations, 2010 CFR

2010-01-01

... PERSONS ON BOARD SUCH AIRCRAFT Crewmember Testing Requirements § 135.301 Crewmember: Tests and checks... a flight check under this part, completes the test or flight check in the calendar month before or... pilot serve, as a flight crewmember in operations under this part until the pilot has satisfactorily...

14 CFR 135.301 - Crewmember: Tests and checks, grace provisions, training to accepted standards.

Code of Federal Regulations, 2012 CFR

2012-01-01

... PERSONS ON BOARD SUCH AIRCRAFT Crewmember Testing Requirements § 135.301 Crewmember: Tests and checks... a flight check under this part, completes the test or flight check in the calendar month before or... pilot serve, as a flight crewmember in operations under this part until the pilot has satisfactorily...

14 CFR 135.301 - Crewmember: Tests and checks, grace provisions, training to accepted standards.

Code of Federal Regulations, 2011 CFR

2011-01-01

... PERSONS ON BOARD SUCH AIRCRAFT Crewmember Testing Requirements § 135.301 Crewmember: Tests and checks... a flight check under this part, completes the test or flight check in the calendar month before or... pilot serve, as a flight crewmember in operations under this part until the pilot has satisfactorily...

14 CFR 135.299 - Pilot in command: Line checks: Routes and airports.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Pilot in command: Line checks: Routes and... Crewmember Testing Requirements § 135.299 Pilot in command: Line checks: Routes and airports. (a) No certificate holder may use a pilot, nor may any person serve, as a pilot in command of a flight unless, since...

14 CFR 135.299 - Pilot in command: Line checks: Routes and airports.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Pilot in command: Line checks: Routes and... Crewmember Testing Requirements § 135.299 Pilot in command: Line checks: Routes and airports. (a) No certificate holder may use a pilot, nor may any person serve, as a pilot in command of a flight unless, since...

14 CFR 135.299 - Pilot in command: Line checks: Routes and airports.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Pilot in command: Line checks: Routes and... Crewmember Testing Requirements § 135.299 Pilot in command: Line checks: Routes and airports. (a) No certificate holder may use a pilot, nor may any person serve, as a pilot in command of a flight unless, since...

14 CFR 135.299 - Pilot in command: Line checks: Routes and airports.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Pilot in command: Line checks: Routes and... Crewmember Testing Requirements § 135.299 Pilot in command: Line checks: Routes and airports. (a) No certificate holder may use a pilot, nor may any person serve, as a pilot in command of a flight unless, since...

14 CFR 135.299 - Pilot in command: Line checks: Routes and airports.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Pilot in command: Line checks: Routes and... Crewmember Testing Requirements § 135.299 Pilot in command: Line checks: Routes and airports. (a) No certificate holder may use a pilot, nor may any person serve, as a pilot in command of a flight unless, since...

HOPE: An On-Line Piloted Handling Qualities Experiment Data Book

NASA Technical Reports Server (NTRS)

Jackson, E. B.; Proffitt, Melissa S.

2010-01-01

A novel on-line database for capturing most of the information obtained during piloted handling qualities experiments (either flight or simulated) is described. The Hyperlinked Overview of Piloted Evaluations (HOPE) web application is based on an open-source object-oriented Web-based front end (Ruby-on-Rails) that can be used with a variety of back-end relational database engines. The hyperlinked, on-line data book approach allows an easily-traversed way of looking at a variety of collected data, including pilot ratings, pilot information, vehicle and configuration characteristics, test maneuvers, and individual flight test cards and repeat runs. It allows for on-line retrieval of pilot comments, both audio and transcribed, as well as time history data retrieval and video playback. Pilot questionnaires are recorded as are pilot biographies. Simple statistics are calculated for each selected group of pilot ratings, allowing multiple ways to aggregate the data set (by pilot, by task, or by vehicle configuration, for example). Any number of per-run or per-task metrics can be captured in the database. The entire run metrics dataset can be downloaded in comma-separated text for further analysis off-line. It is expected that this tool will be made available upon request

UTILIZATION OF TREATABILITY AND PILOT TESTS TO PREDICT CAH BIOREMEDIATION (Battelle)

EPA Science Inventory

Multiple tools have been suggested to help in the design of enhanced anaerobic bioremediation systems for CAHs:
Extensive high quality microcosm testing followed by small-scale, thoroughly observed, induced flow field pilot tests (i.e. RABITT Protocol, Morse 1998)
More...

Healthy Efficient New Gas Homes (HENGH) Pilot Test Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chan, Wanyu R.; Maddalena, Randy L; Stratton, Chris

The Healthy Efficient New Gas Homes (HENGH) is a field study that will collect data on ventilation systems and indoor air quality (IAQ) in new California homes that were built to 2008 Title 24 standards. A pilot test was performed to help inform the most time and cost effective approaches to measuring IAQ in the 100 test homes that will be recruited for this study. Two occupied, single-family detached homes built to 2008 Title 24 participated in the pilot test. One of the test homes uses exhaust-only ventilation provided by a continuous exhaust fan in the laundry room. The othermore » home uses supply air for ventilation. Measurements of IAQ were collected for two weeks. Time-resolved concentrations of particulate matter (PM), nitrogen dioxide (NO2), carbon dioxide (CO2), carbon monoxide (CO), and formaldehyde were measured. Measurements of IAQ also included time-integrated concentrations of volatile organic compounds (VOCs), volatile aldehydes, and NO2. Three perfluorocarbon tracers (PFTs) were used to estimate the dilution rate of an indoor emitted air contaminant in the two pilot test homes. Diagnostic tests were performed to measure envelope air leakage, duct leakage, and airflow of range hood, exhaust fans, and clothes dryer vent when accessible. Occupant activities, such as cooking, use of range hood and exhaust fans, were monitored using various data loggers. This document describes results of the pilot test.« less

HANFORD MEDIUM-LOW CURIE WASTE PRETREATMENT ALTERNATIVES PROJECT FRACTIONAL CRYSTALLIZATION PILOT SCALE TESTING FINAL REPORT

DOE Office of Scientific and Technical Information (OSTI.GOV)

HERTING DL

2008-09-16

The Fractional Crystallization Pilot Plant was designed and constructed to demonstrate that fractional crystallization is a viable way to separate the high-level and low-activity radioactive waste streams from retrieved Hanford single-shell tank saltcake. The focus of this report is to review the design, construction, and testing details of the fractional crystallization pilot plant not previously disseminated.

The Constraints of Ghanaian Polytechnics in Adopting Competency Based Training (CBT): The Case of a Pilot-Tested Programme

ERIC Educational Resources Information Center

Alhassan, Munkaila; Habib, Abdallah Mohammed

2016-01-01

Polytechnics in Ghana view Competency Based Training (CBT) as a major intervention to the perennial constraints confronting its education and training. On the basis of this, and by government policy, a pilot programme of CBT was instituted in all the 10 polytechnics of Ghana, and was pilot tested in, at least, one department. Agricultural…

Pilot Field Test of Electrokinetically-Delivered and Thermally Activated Persulfate (EKTAP) for Remediation of Chlorinated Solvents in Clay

NASA Astrophysics Data System (ADS)

O'Carrol, D. M.; Head, N.; Chowdhury, A. I.; Inglis, A.; Garcia, A. N.; Reynolds, D. A.; Hayman, J.; Hogberg, D.; Austrins, L. M.; Sidebottom, A.; Auger, M.; Eimers, J.; Gerhard, J.

2017-12-01

Remediation of low-permeability soils that are contaminated with chlorinated solvents is challenging. In-situ chemical oxidation (ISCO) with persulfate is promising, however, the delivery of the oxidant by hydraulic gradient is limited in low-permeability soils. Electrokinetic (EK) enhanced transport of amendments has shown the potential to overcome these limitations. In particular, the combined technology of EK-delivered and thermally activated persulfate (EKTAP) has been recently demonstrated in the laboratory as promising in these challenging environments (Chowdhury A. I. (2016) Hydraulic and Electrokinetic Delivery of Remediants for In-situ Remediation. Electronic Thesis and Dissertation Repository, Paper 4135). This study presents the first pilot field test to evaluate EKTAP to enhance the distribution and effectiveness of persulfate in clayey soil. The pilot field test was conducted at a contaminated site formerly occupied by a chlorinated solvent production facility. In the EK transport phase, 925 L of 40 g/L persulfate was injected over 57 days, during which 9A of direct current (DC) was applied between two electrodes spaced 3 m apart. In the subsequent heating phase, 10A of alternate current (AC) was applied across the same electrodes for an additional 70 days. Extensive sampling of soil and groundwater in this EKTAP cell were compared to those from two parallel control cells, one with EK only and one with no electrodes. Results indicated that EK can significantly increase transport rates of persulfate in clayey soil. Persulfate activation primarily occurred in the period of DC application, indicating that the natural reduction capacity of the clay soil had a significant impact on persulfate decomposition. Temperature mapping indicated that AC current was able to increase soil temperatures, validating the EKTAP concept. Degradation of chlorinated compounds, in particular, 1-2, dichloroethane (1,2- DCA), was observed to be substantial in areas of persulfate delivery. Studies are ongoing to evaluate the mineral oxidation of the persulfate and how to optimize the system for both EK and ERH applications. This study nevertheless demonstrates for the first time at the field scale that EKTAP can result in enhanced amendment transport and remediation of low permeability strata.

7 CFR 1955.132 - Pilot projects.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 14 2011-01-01 2011-01-01 false Pilot projects. 1955.132 Section 1955.132 Agriculture... REGULATIONS (CONTINUED) PROPERTY MANAGEMENT Disposal of Inventory Property General § 1955.132 Pilot projects. FmHA or its successor agency under Public Law 103-354 may conduct pilot projects to test policies and...

7 CFR 1955.132 - Pilot projects.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 14 2010-01-01 2009-01-01 true Pilot projects. 1955.132 Section 1955.132 Agriculture... REGULATIONS (CONTINUED) PROPERTY MANAGEMENT Disposal of Inventory Property General § 1955.132 Pilot projects. FmHA or its successor agency under Public Law 103-354 may conduct pilot projects to test policies and...

7 CFR 1955.132 - Pilot projects.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 14 2014-01-01 2014-01-01 false Pilot projects. 1955.132 Section 1955.132 Agriculture... REGULATIONS (CONTINUED) PROPERTY MANAGEMENT Disposal of Inventory Property General § 1955.132 Pilot projects. FmHA or its successor agency under Public Law 103-354 may conduct pilot projects to test policies and...

A cell transportation solution that preserves live circulating tumor cells in patient blood samples.

PubMed

Stefansson, Steingrimur; Adams, Daniel L; Ershler, William B; Le, Huyen; Ho, David H

2016-05-06

Circulating tumor cells (CTCs) are typically collected into CellSave fixative tubes, which kills the cells, but preserves their morphology. Currently, the clinical utility of CTCs is mostly limited to their enumeration. More detailed investigation of CTC biology can be performed on live cells, but obtaining live CTCs is technically challenging, requiring blood collection into biocompatible solutions and rapid isolation which limits transportation options. To overcome the instability of CTCs, we formulated a sugar based cell transportation solution (SBTS) that stabilizes cell viability at ambient temperature. In this study we examined the long term viability of human cancer cell lines, primary cells and CTCs in human blood samples in the SBTS for transportation purposes. Four cell lines, 5 primary human cells and purified human PBMCs were tested to determine the viability of cells stored in the transportation solution at ambient temperature for up to 7 days. We then demonstrated viability of MCF-7 cells spiked into normal blood with SBTS and stored for up to 7 days. A pilot study was then run on blood samples from 3 patients with metastatic malignancies stored with or without SBTS for 6 days. CTCs were then purified by Ficoll separation/microfilter isolation and identified using CTC markers. Cell viability was assessed using trypan blue or CellTracker™ live cell stain. Our results suggest that primary/immortalized cell lines stored in SBTS remain ~90% viable for > 72 h. Further, MCF-7 cells spiked into whole blood remain viable when stored with SBTS for up to 7 days. Finally, live CTCs were isolated from cancer patient blood samples kept in SBTS at ambient temperature for 6 days. No CTCs were isolated from blood samples stored without SBTS. In this proof of principle pilot study we show that viability of cell lines is preserved for days using SBTS. Further, this solution can be used to store patient derived blood samples for eventual isolation of viable CTCs after days of storage. Therefore, we suggest an effective and economical transportation of cancer patient blood samples containing live CTCs can be achieved.

LAM Pilot Study with Imatinib Mesylate (LAMP-1)

DTIC Science & Technology

2017-10-01

AWARD NUMBER: W81XWH-14-1-0132 TITLE: LAM Pilot Study with Imatinib Mesylate (LAMP-1) PRINCIPAL INVESTIGATOR: Charlie Strange, MD...completion dates or the percentage of completion. The LAMP-1 study is designed to generate short-term safety and efficacy data...block the growth of LAM cells through initiation of targeted cell death. This study employs a small clinical trial design using 20 participants at two

CONSTRUCTION PROGRESS PHOTO OF HOT PILOT PLANT (CP640) LOOKING NORTHWEST ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

CONSTRUCTION PROGRESS PHOTO OF HOT PILOT PLANT (CP-640) LOOKING NORTHWEST SHOWING FORMING AND PLACEMENT OF REINFORCING STEEL FOR SOUTH WALLS OF CELLS 1, 3, 4 AND 5 AND WEST WALL FOR CELLS 1 AND 2; CONSTRUCTION 13 PERCENT COMPLETE. INL PHOTO NUMBER NRTS 59-6436. J. Anderson, Photographer, 12/18/1959 - Idaho National Engineering Laboratory, Idaho Chemical Processing Plant, Fuel Reprocessing Complex, Scoville, Butte County, ID

Solar-powered Gossamer Penguin in flight

NASA Technical Reports Server (NTRS)

1979-01-01

Gossamer Penguin in flight above Rogers Dry Lakebed at Edwards, California, showing the solar panel perpendicular to the wing and facing the sun. Background The first flight of a solar-powered aircraft took place on November 4, 1974, when the remotely controlled Sunrise II, designed by Robert J. Boucher of AstroFlight, Inc., flew following a launch from a catapult. Following this event, AeroVironment, Inc. (founded in 1971 by the ultra-light airplane innovator--Dr. Paul MacCready) took on a more ambitious project to design a human-piloted, solar-powered aircraft. The firm initially took the human-powered Gossamer Albatross II and scaled it down to three-quarters of its previous size for solar-powered flight with a human pilot controlling it. This was more easily done because in early 1980 the Gossamer Albatross had participated in a flight research program at NASA Dryden in a program conducted jointly by the Langley and Dryden research centers. Some of the flights were conducted using a small electric motor for power. Gossamer Penguin The scaled-down aircraft was designated the Gossamer Penguin. It had a 71-foot wingspan compared with the 96-foot span of the Gossamer Albatross. Weighing only 68 pounds without a pilot, it had a low power requirement and thus was an excellent test bed for solar power. AstroFlight, Inc., of Venice, Calif., provided the power plant for the Gossamer Penguin, an Astro-40 electric motor. Robert Boucher, designer of the Sunrise II, served as a key consultant for both this aircraft and the Solar Challenger. The power source for the initial flights of the Gossamer Penguin consisted of 28 nickel-cadmium batteries, replaced for the solar-powered flights by a panel of 3,920 solar cells capable of producing 541 Watts of power. The battery-powered flights took place at Shafter Airport near Bakersfield, Calif. Dr. Paul MacCready's son Marshall, who was 13 years old and weighed roughly 80 pounds, served as the initial pilot for these flights to determine the power required to fly the airplane, optimize the airframe/propulsion system, and train the pilot. He made the first flights on April 7, 1980, and made a brief solar-powered flight on May 18. The official project pilot was Janice Brown, a Bakersfield school teacher who weighed in at slightly under 100 pounds and was a charter pilot with commercial, instrument, and glider ratings. She checked out in the plane at Shafter and made about 40 flights under battery and solar power there. Wind direction, turbulence, convection, temperature and radiation at Shafter in mid-summer proved to be less than ideal for Gossamer Penguin because takeoffs required no crosswind and increases in temperature reduced the power output from the solar cells. Consequently, the project moved to Dryden in late July, although conditions there also were not ideal. Nevertheless, Janice finished the testing, and on August 7, 1980, she flew a public demonstration of the aircraft at Dryden in which it went roughly 1.95 miles in 14 minutes and 21 seconds. This was significant as the first sustained flight of an aircraft relying solely on direct solar power rather than batteries. It provided the designers with practical experience for developing a more advanced, solar-powered aircraft, since the Gossamer Penguin was fragile and had limited controllability. This necessitated its flying early in the day when there were minimal wind and turbulence levels, but the angle of the sun was also low, requiring a panel for the solar cells that could be tilted toward the sun. Using the specific conclusions derived from their experience with Gossamer Penguin, the AeroVironment engineers designed Solar Challenger, a piloted, solar-powered aircraft strong enough to handle both long and high flights when encountering normal turbulence.

A mixed method pilot study: the researchers' experiences.

PubMed

Secomb, Jacinta M; Smith, Colleen

2011-08-01

This paper reports on the outcomes of a small well designed pilot study. Pilot studies often disseminate limited or statistically meaningless results without adding to the body knowledge on the comparative research benefits. The design a pre-test post-test group parallel randomised control trial and inductive content analysis of focus group transcripts was tested specifically to increase outcomes in a proposed larger study. Strategies are now in place to overcome operational barriers and recruitment difficulties. Links between the qualitative and quantitative arms of the proposed larger study have been made; it is anticipated that this will add depth to the final report. More extensive reporting on the outcomes of pilot studies would assist researchers and increase the body of knowledge in this area.

Effects of foveal information processing

NASA Technical Reports Server (NTRS)

Harris, R. L., Sr.

1984-01-01

The scanning behavior of pilots must be understood so that cockpit displays can be assembled which will provide the most information accurately and quickly to the pilot. The results of seven years of collecting and analyzing pilot scanning data are summarized. The data indicate that pilot scanning behavior is: (1) subsconscious; (2) situation dependent; and (3) can be disrupted if pilots are forced to make conscious decisions. Testing techniques and scanning analysis techniques have been developed that are sensitive to pilot workload.

Application of Titration-Based Screening for the Rapid Pilot Testing of High-Throughput Assays.

PubMed

Zhang, Ji-Hu; Kang, Zhao B; Ardayfio, Ophelia; Ho, Pei-i; Smith, Thomas; Wallace, Iain; Bowes, Scott; Hill, W Adam; Auld, Douglas S

2014-06-01

Pilot testing of an assay intended for high-throughput screening (HTS) with small compound sets is a necessary but often time-consuming step in the validation of an assay protocol. When the initial testing concentration is less than optimal, this can involve iterative testing at different concentrations to further evaluate the pilot outcome, which can be even more time-consuming. Quantitative HTS (qHTS) enables flexible and rapid collection of assay performance statistics, hits at different concentrations, and concentration-response curves in a single experiment. Here we describe the qHTS process for pilot testing in which eight-point concentration-response curves are produced using an interplate asymmetric dilution protocol in which the first four concentrations are used to represent the range of typical HTS screening concentrations and the last four concentrations are added for robust curve fitting to determine potency/efficacy values. We also describe how these data can be analyzed to predict the frequency of false-positives, false-negatives, hit rates, and confirmation rates for the HTS process as a function of screening concentration. By taking into account the compound pharmacology, this pilot-testing paradigm enables rapid assessment of the assay performance and choosing the optimal concentration for the large-scale HTS in one experiment. © 2013 Society for Laboratory Automation and Screening.

Interrogating the Construct of Aviation English: Feedback from Test Takers in Korea

ERIC Educational Resources Information Center

Kim, Hyejeong; Elder, Catherine

2015-01-01

This paper explores the underlying construct of both the English proficiency test for pilot and air traffic controller radiotelephony communication developed and administered in Korea and the ICAO language proficiency testing policy on which the test in Korea is based. It does so by canvassing the opinions of Korean airline pilots and air traffic…

46 CFR 163.002-21 - Approval tests.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 6 2014-10-01 2014-10-01 false Approval tests. 163.002-21 Section 163.002-21 Shipping...: SPECIFICATIONS AND APPROVAL CONSTRUCTION Pilot Hoist § 163.002-21 Approval tests. (a) General. If a pilot hoist fails one of the tests in this section the cause of the failure must be identified and any needed design...

Officer Career Development: Longitudinal Sample--Fiscal Years 1986-1987

DTIC Science & Technology

1991-10-01

XO-Fleet Replacement Squadron (RAG) 4. CO-Fleet Replacement Squadron (RAG) 5. Test Pilot School 6. Washington Tour 7. Wing Staff 8. Naval Aviation...2535 4. CO -RAG E9E6 - - - - - - - 1 2536 5. Test Pilot E9E7 - - - - - - - 1 2537 6. Wash. Tour E9E9 - - - - - - - 1 2538 1. Wing Staff E9E1O - 2539...for department head (VP community only) 12. Screening for Test Pilot school (omit if not applicable) RESPONSE SCALE: 1. Little Or No Change 2. 3. A

Flight test experience and controlled impact of a remotely piloted jet transport aircraft

NASA Technical Reports Server (NTRS)

Horton, Timothy W.; Kempel, Robert W.

1988-01-01

The Dryden Flight Research Center Facility of NASA Ames Research Center (Ames-Dryden) and the FAA conducted the controlled impact demonstration (CID) program using a large, four-engine, remotely piloted jet transport airplane. Closed-loop primary flight was controlled through the existing onboard PB-20D autopilot which had been modified for the CID program. Uplink commands were sent from a ground-based cockpit and digital computer in conjunction with an up-down telemetry link. These uplink commands were received aboard the airplane and transferred through uplink interface systems to the modified PB-20D autopilot. Both proportional and discrete commands were produced by the ground system. Prior to flight tests, extensive simulation was conducted during the development of ground-based digital control laws. The control laws included primary control, secondary control, and racetrack and final approach guidance. Extensive ground checks were performed on all remotely piloted systems; however, piloted flight tests were the primary method and validation of control law concepts developed from simulation. The design, development, and flight testing of control laws and systems required to accomplish the remotely piloted mission are discussed.

Advanced Weather Awareness and Reporting Enhancements

NASA Technical Reports Server (NTRS)

Busquets, Anthony M. (Technical Monitor); Ruokangas, Corinne Clinton; Kelly, Wallace E., III

2005-01-01

AWARE (Aviation Weather Awareness and Reporting Enhancements) was a NASA Cooperative Research and Development program conducted jointly by Rockwell Scientific, Rockwell Collins, and NASA. The effort culminated in an enhanced weather briefing and reporting tool prototype designed to integrate graphical and text-based aviation weather data to provide clear situational awareness in the context of a specific pilot, flight and equipment profile. The initial implementation of AWARE was as a web-based preflight planning tool, specifically for general aviation pilots, who do not have access to support such as the dispatchers available for commercial airlines. Initial usability tests showed that for VFR (Visual Flight Rules) pilots, AWARE provided faster and more effective weather evaluation. In a subsequent formal usability test for IFR (Instrument Flight Rules) pilots, all users finished the AWARE tests faster than the parallel DUAT tests, and all subjects graded AWARE higher for effectiveness, efficiency, and usability. The decision analysis basis of AWARE differentiates it from other aviation safety programs, providing analysis of context-sensitive data in a personalized graphical format to aid pilots/dispatchers in their complex flight requirements.

Airline Transport Pilot-Airplane (Air Carrier) Written Test Guide.

ERIC Educational Resources Information Center

Federal Aviation Administration (DOT), Washington, DC. Flight Standards Service.

Presented is information useful to applicants who are preparing for the Airline Transport Pilot-Airplane (Air Carrier) Written Test. The guide describes the basic aeronautical knowledge and associated requirements for certification, as well as information on source material, instructions for taking the official test, and questions that are…

STS-99 Pilot Gorie arrives for launch

NASA Technical Reports Server (NTRS)

2000-01-01

STS-99 Pilot Dominic Gorie arrives at KSC aboard a T-38 jet aircraft to prepare for launch of Endeavour Jan. 31 at 12:47 p.m. EST. Over the next few days, the crew will review mission procedures, conduct test flights in the Shuttle Training Aircraft and undergo routine preflight medical exams. STS-99 is the Shuttle Radar Topography Mission, which will chart a new course, using two antennae and a 200-foot-long section of space station- derived mast protruding from the payload bay to produce unrivaled 3-D images of the Earth's surface. The result of the Shuttle Radar Topography Mission could be close to 1 trillion measurements of the Earth's topography. Besides contributing to the production of better maps, these measurements could lead to improved water drainage modeling, more realistic flight simulators, better locations for cell phone towers, and enhanced navigation safety.

STS-88 Day 11 Highlights

NASA Technical Reports Server (NTRS)

1998-01-01

On this eleventh day of the STS-88 mission, the flight crew, Commander Robert D. Cabana, Pilot Frederick W. Sturckow, and Mission Specialists Nancy J. Currie, James H. Newman, Jerry L. Ross, and Sergei Krikalev are awakened with the song "Goodnight, Sweetheart, Goodnight". Pilot Rick Sturckow undocks Endeavour from the station and backs the shuttle away to a distance of 450 feet above the station before beginning a nose-forward fly-around. Later Cabana, Sturckow and Ross deploy the SAC-A satellite from Endeavour's payload bay. SAC-A is a small, self-contained, non-recoverable satellite built by the Argentinean National Commission of Space Activities. The cube-shaped, 590-pound satellite will test and characterize the performance of new equipment and technologies that may be used in future scientific or operational missions. The payload includes a differential global positioning system, a magnetometer, silicon solar cells, a charge-coupled device Earth camera and a whale tracker experiment.

46 CFR 163.003-1 - Scope.

Code of Federal Regulations, 2010 CFR

2010-10-01

... production tests for a pilot ladder used on a merchant vessel to embark and disembark pilots and other persons when away from the dock. (b) The requirements in this subpart apply to a pilot ladder designed for...

Stakeholder Engagement/Capacity Building Pilot Opportunity FAQ

EPA Pesticide Factsheets

Frequently Asked Questions (FAQs) about the pilot opportunity for stakeholder engagement/capacity building. EPA is offering an opportunity for community stakeholders and ports to participate in a pilot project to test and refine capacity building tools.

CONCEPTUAL DESIGN ASSESSMENT FOR THE CO-FIRING OF BIO-REFINERY SUPPLIED LIGNIN PROJECT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ted Berglund; Jeffrey T. Ranney; Carol L. Babb

2001-01-01

The major aspects of this project are proceeding toward completion. Prior to this quarter, design criteria, tentative site selection, facility layout, and preliminary facility cost estimates have been completed and issued for review. Processing of bio-solids was completed, providing material for the pilot operations. Pilot facility design, equipment selection, and modification were completed during the fourth quarter. Initial pilot facility shakedown was completed during the fourth quarter. During pilot plant shakedown operations, several production batch test runs were performed. These pilot tests were coupled with laboratory testing to confirm pilot results. In initial batches of operations, cellulose to glucose conversionsmore » of 62.5% and 64.8% were observed in laboratory hydrolysis. As part of this testing, lignin dewatering was tested using laboratory and vendor-supplied filtration equipment. Dewatering tests reported moisture contents in the lignin of between 50% and 60%. Dewatering parameters and options will continue to be investigated during lignin production. After some unavoidable delays, a suitable representative supply of MSW feed material was procured. Shredding of the feed material was completed and final drying of the feed is expected to be completed by late January. Once feed drying is completed, pilot facility production will begin to produce lignin for co-fire testing. Facility modifications are expected to continue to improve facility operations and performance during the first quarter of 2001. The TVA-Colbert facility continues to make progress in evaluating the co-location of the Masada facility on the operation of the power generation facility. The TVA-Colbert fossil plant is fully capable of providing a reliable steam supply. The preferred steam supply connection points and steam pipeline routing have been identified. The environmental review of the pipeline routing has been completed and no major impacts have been identified. Detailed assessment of steam export impacts on the Colbert boiler system continues.« less

Manned Systems Utilization Analysis. Study 2.1: Space Servicing Pilot Program Study. [for automated payloads

NASA Technical Reports Server (NTRS)

Wolfe, R. R.

1975-01-01

Space servicing automated payloads was studied for potential cost benefits for future payload operations. Background information is provided on space servicing in general, and on a pilot flight test program in particular. An fight test is recommended to demonstrate space servicing. An overall program plan is provided which builds upon the pilot program through an interim servicing capability. A multipayload servicing concept for the time when the full capability tug becomes operational is presented. The space test program is specifically designed to provide low-cost booster vehicles and a flight test platform for several experiments on a single flight.

Enhanced Weather Radar (EWxR) System

NASA Technical Reports Server (NTRS)

Kronfeld, Kevin M. (Technical Monitor)

2003-01-01

An airborne weather radar system, the Enhanced Weather Radar (EWxR), with enhanced on-board weather radar data processing was developed and tested. The system features additional weather data that is uplinked from ground-based sources, specialized data processing, and limited automatic radar control to search for hazardous weather. National Weather Service (NWS) ground-based Next Generation Radar (NEXRAD) information is used by the EWxR system to augment the on-board weather radar information. The system will simultaneously display NEXRAD and on-board weather radar information in a split-view format. The on-board weather radar includes an automated or hands-free storm-finding feature that optimizes the radar returns by automatically adjusting the tilt and range settings for the current altitude above the terrain and searches for storm cells near the atmospheric 0-degree isotherm. A rule-based decision aid was developed to automatically characterize cells as hazardous, possibly-hazardous, or non-hazardous based upon attributes of that cell. Cell attributes are determined based on data from the on-board radar and from ground-based radars. A flight path impact prediction algorithm was developed to help pilots to avoid hazardous weather along their flight plan and their mission. During development the system was tested on the NASA B757 aircraft and final tests were conducted on the Rockwell Collins Sabreliner.

14 CFR 135.297 - Pilot in command: Instrument proficiency check requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Pilot in command: Instrument proficiency... ON BOARD SUCH AIRCRAFT Crewmember Testing Requirements § 135.297 Pilot in command: Instrument... pilot in command of an aircraft under IFR unless, since the beginning of the 6th calendar month before...

14 CFR 135.297 - Pilot in command: Instrument proficiency check requirements.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Pilot in command: Instrument proficiency... ON BOARD SUCH AIRCRAFT Crewmember Testing Requirements § 135.297 Pilot in command: Instrument... pilot in command of an aircraft under IFR unless, since the beginning of the 6th calendar month before...

14 CFR 135.297 - Pilot in command: Instrument proficiency check requirements.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Pilot in command: Instrument proficiency... ON BOARD SUCH AIRCRAFT Crewmember Testing Requirements § 135.297 Pilot in command: Instrument... pilot in command of an aircraft under IFR unless, since the beginning of the 6th calendar month before...

14 CFR 135.297 - Pilot in command: Instrument proficiency check requirements.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Pilot in command: Instrument proficiency... ON BOARD SUCH AIRCRAFT Crewmember Testing Requirements § 135.297 Pilot in command: Instrument... pilot in command of an aircraft under IFR unless, since the beginning of the 6th calendar month before...

14 CFR 135.297 - Pilot in command: Instrument proficiency check requirements.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Pilot in command: Instrument proficiency... ON BOARD SUCH AIRCRAFT Crewmember Testing Requirements § 135.297 Pilot in command: Instrument... pilot in command of an aircraft under IFR unless, since the beginning of the 6th calendar month before...

Mandibular position influence on pilots' postural balance analyzed under dynamic conditions.

PubMed

Baldini, Alberto; Nota, Alessandro; Cioffi, Clementina; Ballanti, Fabiana; Tecco, Simona

2017-11-01

The aim of this study is to evaluate the influence of the mandibular position on the postural stability in a sample of civilian and military pilots. Twenty military pilots (males, mean age 35.15 ± 3.14 years) and 17 civilian pilots (males, mean 34.91 ± 2.15 years) were enrolled in this study and underwent a Sensory Organization Test (SOT) using the EquiTest® (NeuroCom International Inc., Clackamas, OR, USA) computerized dynamic posturography. The composite parameter was recorded and analyzed. The equilibrium score (ES) recorded in centric occlusion is slightly higher than the ES recorded in mandibular rest position; civilian pilots showed ESs slightly higher than military pilots. The two-way ANOVA analysis shows these differences are not statistically significant. The findings of this study seem to suggest that the composite parameter of the SOT is not sensitive in analyzing the influence of the stomatognathic system on the postural balance of civilian and military pilots.

Frank Batteas

NASA Image and Video Library

1999-01-04

Frank Batteas is a research test pilot in the Flight Crew Branch of NASA's Dryden Flight Research Center, Edwards, California. He is currently a project pilot for the F/A-18 and C-17 flight research projects. In addition, his flying duties include operation of the DC-8 Flying Laboratory in the Airborne Science program, and piloting the B-52B launch aircraft, the King Air, and the T-34C support aircraft. Batteas has accumulated more than 4,700 hours of military and civilian flight experience in more than 40 different aircraft types. Batteas came to NASA Dryden in April 1998, following a career in the U.S. Air Force. His last assignment was at Wright-Patterson Air Force Base, Dayton, Ohio, where Lieutenant Colonel Batteas led the B-2 Systems Test and Evaluation efforts for a two-year period. Batteas graduated from Class 88A of the Air Force Test Pilot School, Edwards Air Force Base, California, in December 1988. He served more than five years as a test pilot for the Air Force's newest airlifter, the C-17, involved in nearly every phase of testing from flutter and high angle-of-attack tests to airdrop and air refueling envelope expansion. In the process, he achieved several C-17 firsts including the first day and night aerial refuelings, the first flight over the North Pole, and a payload-to-altitude world aviation record. As a KC-135 test pilot, he also was involved in aerial refueling certification tests on a number of other Air Force aircraft. Batteas received his commission as a second lieutenant in the U. S. Air Force through the Reserve Officer Training Corps and served initially as an engineer working on the Peacekeeper and Minuteman missile programs at the Ballistic Missile Office, Norton Air Force Base, Calif. After attending pilot training at Williams Air Force Base, Phoenix, Ariz., he flew operational flights in the KC-135 tanker aircraft and then was assigned to research flying at the 4950th Test Wing, Wright-Patterson. He flew extensively modified C-135

Lack of international uniformity in assessing color vision deficiency in professional pilots.

PubMed

Watson, Dougal B

2014-02-01

Color is an important characteristic of the aviation environment. Pilots must rapidly and accurately differentiate and identify colors. The medical standards published by the International Civil Aviation Organization (ICAO) require that pilots have "the ability to perceive readily those colors the perception of which is necessary for the safe performance of duties." The general wording of that color vision (CV) standard, coupled with the associated flexibility provisions, allows for different approaches to the assessment of color vision deficient (CVD) pilots. Data was gathered and analyzed regarding medical assessment practices applied by different countries to CVD pilots. Data was obtained from 78 countries, representing 78% of the population and 92% of the aviation activity of the world. That data indicates wide variation in the medical assessment of CVD pilots. Countries use different tools and procedures for the testing of pilots, and also apply different result criteria to those tests. At one extreme an applicant making one error upon Ishihara 24-plate pseudoisochromatic plate (PIP) testing is declined a class 1 medical assessment, while at another extreme an applicant failing every color vision test required by the regulatory authority may be issued a medical assessment allowing commercial and airline copilot privileges. The medical assessment of CVD applicants is not performed consistently across the world. Factors that favor uniformity have been inadequate to encourage countries toward consistent medical assessment outcomes. This data is not consistent with the highest practicable degree of uniformity in medical assessment outcomes, and encourages aeromedical tourism.

Cockpit weather information needs

NASA Technical Reports Server (NTRS)

Scanlon, Charles H.

1992-01-01

The primary objective is to develop an advanced pilot weather interface for the flight deck and to measure its utilization and effectiveness in pilot reroute decision processes, weather situation awareness, and weather monitoring. Identical graphical weather displays for the dispatcher, air traffic control (ATC), and pilot crew should also enhance the dialogue capabilities for reroute decisions. By utilizing a broadcast data link for surface observations, forecasts, radar summaries, lightning strikes, and weather alerts, onboard weather computing facilities construct graphical displays, historical weather displays, color textual displays, and other tools to assist the pilot crew. Since the weather data is continually being received and stored by the airborne system, the pilot crew has instantaneous access to the latest information. This information is color coded to distinguish degrees of category for surface observations, ceiling and visibilities, and ground radar summaries. Automatic weather monitoring and pilot crew alerting is accomplished by the airborne computing facilities. When a new weather information is received, the displays are instantaneously changed to reflect the new information. Also, when a new surface or special observation for the intended destination is received, the pilot crew is informed so that information can be studied at the pilot's discretion. The pilot crew is also immediately alerted when a severe weather notice, AIRMET or SIGMET, is received. The cockpit weather display shares a multicolor eight inch cathode ray tube and overlaid touch panel with a pilot crew data link interface. Touch sensitive buttons and areas are used for pilot selection of graphical and data link displays. Time critical ATC messages are presented in a small window that overlays other displays so that immediate pilot alerting and action can be taken. Predeparture and reroute clearances are displayed on the graphical weather system so pilot review of weather along the route can be accomplished prior to pilot acceptance of the clearance. An ongoing multiphase test series is planned for testing and modifying the graphical weather system. Preliminary data shows that the nine test subjects considered the graphical presentation to be much better than their current weather information source for situation awareness, flight safety, and reroute decision making.

Development of systems and techniques for landing an aircraft using onboard television

NASA Technical Reports Server (NTRS)

Gee, S. W.; Carr, P. C.; Winter, W. R.; Manke, J. A.

1978-01-01

A flight program was conducted to develop a landing technique with which a pilot could consistently and safely land a remotely piloted research vehicle (RPRV) without outside visual reference except through television. Otherwise, instrumentation was standard. Such factors as the selection of video parameters, the pilot's understanding of the television presentation, the pilot's ground cockpit environment, and the operational procedures for landing were considered. About 30 landings were necessary for a pilot to become sufficiently familiar and competent with the test aircraft to make powered approaches and landings with outside visual references only through television. When steep approaches and landings were made by remote control, the pilot's workload was extremely high. The test aircraft was used as a simulator for the F-15 RPRV, and as such was considered to be essential to the success of landing the F-15 RPRV.

High-Alpha Research Vehicle (HARV) longitudinal controller: Design, analyses, and simulation resultss

NASA Technical Reports Server (NTRS)

Ostroff, Aaron J.; Hoffler, Keith D.; Proffitt, Melissa S.; Brown, Philip W.; Phillips, Michael R.; Rivers, Robert A.; Messina, Michael D.; Carzoo, Susan W.; Bacon, Barton J.; Foster, John F.

1994-01-01

This paper describes the design, analysis, and nonlinear simulation results (batch and piloted) for a longitudinal controller which is scheduled to be flight-tested on the High-Alpha Research Vehicle (HARV). The HARV is an F-18 airplane modified for and equipped with multi-axis thrust vectoring. The paper includes a description of the facilities, a detailed review of the feedback controller design, linear analysis results of the feedback controller, a description of the feed-forward controller design, nonlinear batch simulation results, and piloted simulation results. Batch simulation results include maximum pitch stick agility responses, angle of attack alpha captures, and alpha regulation for full lateral stick rolls at several alpha's. Piloted simulation results include task descriptions for several types of maneuvers, task guidelines, the corresponding Cooper-Harper ratings from three test pilots, and some pilot comments. The ratings show that desirable criteria are achieved for almost all of the piloted simulation tasks.

Pilot Study of Umbilical Cord Blood Transplantation in Adult Patient With Advanced Hematopoietic Malignancies

ClinicalTrials.gov

2013-08-13

Acute Myeloid Leukemia; Myelodysplasia; Acute Lymphoblastic Leukemia; Chronic Myelogenous Leukemia; Multiple Myeloma; Lymphoma, Large-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, T-Cell, Peripheral; T-NK Cell Lymphoma; Hodgkin Disease

Neck proprioception, strength, flexibility, and posture in pilots with and without neck pain history.

PubMed

Nagai, Takashi; Abt, John P; Sell, Timothy C; Clark, Nicholas C; Smalley, Brian W; Wirt, Michael D; Lephart, Scott M

2014-05-01

Neck pain (NP) is common among military helicopter pilots. Older age and more flight-hours have been associated with pilots with a history of NP. However, modifiable neuromuscular and musculoskeletal characteristics such as neck proprioception, strength, flexibility, and posture have rarely been investigated in military helicopter pilots with a history of NP. The purpose of the study was to compare demographics, flight characteristics, physical fitness information, neck proprioception, strength, flexibility, and posture between helicopter pilots with and without a history of NP. A total of 27 Army helicopter pilots with NP in the past 12 mo (pain group) were matched based on age with pilots without a history of NP (nonpain group). All pilots had flown at least 100 h in the past 12 mo and were cleared for flight and physical training. All pilots completed a battery of laboratory testing: neck proprioception, neck and scapular muscular strength, neck active range-of-motion (ROM), forward head and shoulder posture, and pectoralis minor length. Paired t-tests or Wilcoxon tests were used to compare differences between groups. The pain group had significantly less cervical extension (63.7 +/- 8.5 degrees) and rotation ROM (R rotation: 67.7 +/- 8.8 degrees; L rotation: 67.4 +/- 9.0 degrees) when compared to the nonpain group (extension: 68.3 +/- 7.4 degrees; R rotation: 73.4 +/- 7.4 degrees; L rotation: 72.9 +/- 6.8 degrees). No significant differences were found for other variables. The results demonstrate less neck active ROM in pilots with a history of NP. Operating a helicopter with limited neck ROM or NP may negatively impact flight safety and force readiness. Continued research is warranted.

Work zone performance measures pilot test.

DOT National Transportation Integrated Search

2011-04-01

Currently, a well-defined and validated set of metrics to use in monitoring work zone performance do not : exist. This pilot test was conducted to assist state DOTs in identifying what work zone performance : measures can and should be targeted, what...

Sickle Cell Screening: Emphasis on Education

ERIC Educational Resources Information Center

Valente, Carmine; Frank, William

1972-01-01

This article relates the sickle cell education program, the personnel training and the screening procedures of a pilot sickle cell screening program by the Prince George's County Health Department. (JA)

Evaluating the Pilot Narnian Virtues Character Education English Curriculum Project: A Study among 11- to 13-Year-Old Students

ERIC Educational Resources Information Center

Francis, Leslie J.; Pike, Mark A.; Lickona, Thomas; Lankshear, David W.; Nesfield, Victoria

2018-01-01

In order to evaluate the impact of the pilot Narnian Virtues Character Education English Curriculum Project, a pilot sample of 86 year 7 and year 8 students (11 to 13 years of age) completed a battery of tests both before and after participating for six weeks in the programme. The battery of tests comprised 12 Narnian Character Virtue Scales…

Pasadena City College SIGI Project Research Design. Pilot Study.

ERIC Educational Resources Information Center

Risser, John J.; Tulley, John E.

A pilot study evaluation of SIGI (System of Interactive Guidance and Information) at Pasadena City College in 1974-75 tested the effectiveness of an experimental research design for an expanded field test of the system the following year. (SIGI is a computer based career guidance program designed by Educational Testing Service to assist community…

AeroVironment's Jim Daley, Rik Meininger, Derek Lisoski and Wyatt Sadler (clockwise from bottom left) closely monitor systems testing of the Pathfinder-Plus.

NASA Image and Video Library

2004-09-17

AeroVironment's test director Jim Daley, backup pilot Rik Meininger, stability and controls engineer Derek Lisoski and pilot Wyatt Sadler (clockwise from bottom left) closely monitor systems testing of the Pathfinder-Plus solar aircraft from the control station.

FAA Pilot Knowledge Tests: Learning or Rote Memorization?

NASA Technical Reports Server (NTRS)

Casner, Stephen M.; Jones, Karen M.; Puentes, Antonio; Irani, Homi

2004-01-01

The FAA pilot knowledge test is a multiple-choice assessment tool designed to measure the extent to which applicants for FAA pilot certificates and ratings have mastered a corpus of required aeronautical knowledge. All questions that appear on the test are drawn from a database of questions that is made available to the public. The FAA and others are concerned that releasing test questions may encourage students to focus their study on memorizing test questions. To investigate this concern, we created our own database of questions that differed from FAA questions in four different ways. Our first three question types were derived by modifying existing FAA questions: (1) rewording questions and answers; (2) shuffling answers; and (3) substituting different figures for problems that used figures. Our last question type posed a question about required knowledge for which no FAA question currently exists. Forty-eight student pilots completed one of two paper-and-pencil knowledge tests that contained a mix of these experimental questions. The results indicate significantly lower scores for some question types when compared to unaltered FAA questions to which participants had prior access.

Development of the Military Women's Attitudes Toward Menstrual Suppression Scale: from construct definition to pilot testing.

PubMed

Trego, Lori L

2009-01-01

The Military Women's Attitudes Toward Menstrual Suppression scale (MWATMS) was created to measure attitudes toward menstrual suppression during deployment. The human health and social ecology theories were integrated to conceptualize an instrument that accounts for military-unique aspects of the environment on attitudes toward suppression. A three-step instrument development process was followed to develop the MWATMS. The instrument was pilot tested on a convenience sample of 206 military women with deployment experience. Reliability was tested with measures of internal consistency (alpha = .97); validity was tested with principal components analysis with varimax rotation. Four components accounted for 65% of variance: Benefits/Interest, Hygiene, Convenience, and Soldier/Stress. The pilot test of the MWATMS supported its reliability and validity. Further testing is warranted for validation of this instrument.

Acceleration effects on neck muscle strength: pilots vs. non-pilots.

PubMed

Seng, Kok-Yong; Lam, Pin-Min; Lee, Vee-Sin

2003-02-01

Conditioning of neck muscles, if any, due to repeated exposures to +Gz forces has received little research attention. This study was conducted to evaluate and compare the neck muscle strength of test volunteers representative of the general populations of fighter aircraft pilots and non-pilots. The tests were performed using a special attachment device on a computerized dynamometer. Ten pilots and ten non-pilots volunteered as test subjects. Each individual's maximal isometric neck muscle strength was evaluated in the extension, flexion, and left and right lateral bending directions in a single day. Peak values from the measurements were used for data analysis. Overall neck strength was calculated as the mean values for the four directions in each group. The overall muscular strength of the necks of pilots did not differ significantly from that of non-pilots, nor did exposure to +Gz forces lead to specific changes in isometric muscle strength across any of the four principal directions. Neck muscle strength in the four measured directions pooled across the two subgroups were statistically significant. The widespread practice of adopting protective head-positioning strategies to minimize neck strains, coupled with results from this research study, suggest that the neck muscles are subjected to reduced in-flight strengthening workouts during exposures to +Gz forces. To maximize in-flight performance and minimize +Gz-induced neck injuries, fighter pilots should be encouraged to perform on-land neck muscle strengthening exercise and in-flight head-positioning techniques. More research is needed to fine-tune this countermeasure strategy against cervical spine injury.

Direct quantitative detection for cell-free miR-155 in urine: a potential role in diagnosis and prognosis for non-muscle invasive bladder cancer.

PubMed

Zhang, Xin; Zhang, Yanli; Liu, Xinfeng; Fang, Aiju; Wang, Jinfeng; Yang, Yongmei; Wang, Lili; Du, Lutao; Wang, Chuanxin

2016-01-19

High recurrence rates of non-muscle invasive bladder cancer (NMIBC) in patients require lifelong testing and monitoring. The aim of this study is to develop a simplified RT-qPCR method (RT-qPCR-D) which directly quantifies cell-free miR-155 in urine without RNA extraction, and assess it as a potential tool in NMIBC detection. A pilot study including 60 urine samples was used to investigate the feasibility of RT-qPCR-D in detecting cell-free miR-155. Then, miR-155 levels were quantified in a large independent cohort of urine from 162 NIMBC patients, 76 cystitis patients, and 86 healthy donors using the RT-qPCR-D method. Changes of cell-free miR-155 before and after operation were also analyzed in 32 NIMBC patients. In pilot study, we found a significant linear association between RT-qPCR and RT-qPCR-D in urinary miR-155 detection. Both methods showed cell-free miR-155 were significantly increased in NMIBC patients, and could reflect their expression in tissues. Then, the increased expression of cell-free miR-155 was successfully validated in 162 NIMBC patients when compared with cystitis patients and healthy donors. Moreover, it distinguished NMIBC patients from others with 80.2% sensitivity and 84.6% specificity, which was superior to urine cytology. Cell-free miR-155 correlated with NMIBC stage and grade, and was an independent factor for predicting recurrence and progression to muscle invasion. In addition, cell-free miR-155 was significantly decreased after NMIBC patients underwent transurethral bladder resection. In conclusion, detection of cell-free miR-155 in urine using RT-qPCR-D is a simple and noninvasive approach which may be used for NMIBC diagnosis and prognosis prediction.

A CBPR Partnership Increases HIV Testing among Men Who Have Sex with Men (MSM): Outcome Findings from a Pilot Test of the "CyBER/Testing" Internet Intervention

ERIC Educational Resources Information Center

Rhodes, Scott D.; Vissman, Aaron T.; Stowers, Jason; Miller, Cindy; McCoy, Thomas P.; Hergenrather, Kenneth C.; Wilkin, Aimee M.; Reece, Michael; Bachmann, Laura H.; Ore, Addison; Ross, Michael W.; Hendrix, Ellen; Eng, Eugenia

2011-01-01

The Internet has emerged as an important tool for the delivery of health promotion and disease prevention interventions. Our community-based participatory research (CBPR) partnership developed and piloted "CyBER/testing", a culturally congruent intervention designed to promote HIV testing among men who have sex with men (MSM) within existing…

Field Testing of a Wet FGD Additive for Enhanced Mercury Control - Task 5 Full-Scale Test Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gary Blythe; MariJon Owens

2007-12-01

This Topical Report summarizes progress on Cooperative Agreement DE-FC26-04NT42309, 'Field Testing of a Wet FGD Additive'. The objective of the project is to demonstrate the use of two flue gas desulfurization (FGD) additives, Evonik Degussa Corporation's TMT-15 and Nalco Company's Nalco 8034, to prevent the re-emission of elemental mercury (Hg{sup 0}) in flue gas exiting wet FGD systems on coal-fired boilers. Furthermore, the project intends to demonstrate whether the additive can be used to precipitate most of the mercury (Hg) removed in the wet FGD system as a fine salt that can be separated from the FGD liquor and bulkmore » solid byproducts for separate disposal. The project is conducting pilot- and full-scale tests of the additives in wet FGD absorbers. The tests are intended to determine required additive dosages to prevent Hg{sup 0} re-emissions and to separate mercury from the normal FGD byproducts for three coal types: Texas lignite/Powder River Basin (PRB) coal blend, high-sulfur Eastern bituminous coal, and low-sulfur Eastern bituminous coal. The project team consists of URS Group, Inc., EPRI, Luminant Power (was TXU Generation Company LP), Southern Company, IPL (an AES company), Evonik Degussa Corporation and the Nalco Company. Luminant Power has provided the Texas lignite/PRB co-fired test site for pilot FGD tests and cost sharing. Southern Company has provided the low-sulfur Eastern bituminous coal host site for wet scrubbing tests, as well as the pilot- and full-scale jet bubbling reactor (JBR) FGD systems tested. IPL provided the high-sulfur Eastern bituminous coal full-scale FGD test site and cost sharing. Evonik Degussa Corporation is providing the TMT-15 additive, and the Nalco Company is providing the Nalco 8034 additive. Both companies are also supplying technical support to the test program as in-kind cost sharing. The project is being conducted in six tasks. Of the six project tasks, Task 1 involves project planning and Task 6 involves management and reporting. The other four tasks involve field testing on FGD systems, either at pilot or full scale. The four tasks include: Task 2 - Pilot Additive Testing in Texas Lignite Flue Gas; Task 3 - Full-scale FGD Additive Testing in High-sulfur Eastern Bituminous Flue Gas; Task 4 - Pilot Wet Scrubber Additive Tests at Plant Yates; and Task 5 - Full-scale Additive Tests at Plant Yates. The pilot-scale tests and the full-scale test using high-sulfur coal were completed in 2005 and 2006 and have been previously reported. This topical report presents the results from the Task 5 full-scale additive tests, conducted at Southern Company's Plant Yates Unit 1. Both additives were tested there.« less

Integrated vehicle-based safety systems (IVBSS) : heavy truck extended pilot test summary report.

DOT National Transportation Integrated Search

2009-05-01

This report describes the findings and recommendations from the heavy-truck (HT) extended pilot test (EPT) conducted by University of Michigan Transportation Research Institute (UMTRI) and its partners under the Integrated Vehicle-Based Safety System...

Functional test measures as risk indicators for low back pain among fixed-wing military pilots.

PubMed

Honkanen, Tuomas; Kyröläinen, H; Avela, J; Mäntysaari, M

2017-02-01

The purpose of this study was to find out the risk value of functional fitness test (FFT) results for low back pain (LBP) among fixed-wing military pilots. A total of 104 male military pilots were recruited for this study. The study was conducted with a self-administered questionnaire and FFT. The functional tests were performed in the beginning of study (baseline). The questionnaire was carried out at the baseline and 5 years later. The isometric low back endurance test result was associated with physical activity-related LBP experienced 5 years later. Demographic information was not associated with LBP. The prevalence of overall LBP was 71% and the flight-related LBP prevalence was 31% at the baseline. Our findings show that LBP among military pilots is a common problem but it is also associated with tasks other than flying. The functional test results were not associated with flight-related LBP but adequate isometric back endurance may have protective role in LBP caused in physical activities. When trying to find the pilots with increased risk of flight-related LBP, a more sensitive set of tests should be considered. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

Comprehension of confidence intervals - development and piloting of patient information materials for people with multiple sclerosis: qualitative study and pilot randomised controlled trial.

PubMed

Rahn, Anne C; Backhus, Imke; Fuest, Franz; Riemann-Lorenz, Karin; Köpke, Sascha; van de Roemer, Adrianus; Mühlhauser, Ingrid; Heesen, Christoph

2016-09-20

Presentation of confidence intervals alongside information about treatment effects can support informed treatment choices in people with multiple sclerosis. We aimed to develop and pilot-test different written patient information materials explaining confidence intervals in people with relapsing-remitting multiple sclerosis. Further, a questionnaire on comprehension of confidence intervals was developed and piloted. We developed different patient information versions aiming to explain confidence intervals. We used an illustrative example to test three different approaches: (1) short version, (2) "average weight" version and (3) "worm prophylaxis" version. Interviews were conducted using think-aloud and teach-back approaches to test feasibility and analysed using qualitative content analysis. To assess comprehension of confidence intervals, a six-item multiple choice questionnaire was developed and tested in a pilot randomised controlled trial using the online survey software UNIPARK. Here, the average weight version (intervention group) was tested against a standard patient information version on confidence intervals (control group). People with multiple sclerosis were invited to take part using existing mailing-lists of people with multiple sclerosis in Germany and were randomised using the UNIPARK algorithm. Participants were blinded towards group allocation. Primary endpoint was comprehension of confidence intervals, assessed with the six-item multiple choice questionnaire with six points representing perfect knowledge. Feasibility of the patient information versions was tested with 16 people with multiple sclerosis. For the pilot randomised controlled trial, 64 people with multiple sclerosis were randomised (intervention group: n = 36; control group: n = 28). More questions were answered correctly in the intervention group compared to the control group (mean 4.8 vs 3.8, mean difference 1.1 (95 % CI 0.42-1.69), p = 0.002). The questionnaire's internal consistency was moderate (Cronbach's alpha = 0.56). The pilot-phase shows promising results concerning acceptability and feasibility. Pilot randomised controlled trial results indicate that the patient information is well understood and that knowledge gain on confidence intervals can be assessed with a set of six questions. German Clinical Trials Register: DRKS00008561 . Registered 8th of June 2015.

Kelly Latimer

NASA Image and Video Library

2007-03-09

Kelly Latimer is a research pilot in the Flight Crew Branch of NASA's Dryden Flight Research Center, Edwards, Calif. Latimer joined NASA in March 2007 and will fly the T38, T-34, G-III, C-17 and the "Ikhana" Predator B. Latimer is Dryden's first female research test pilot. Prior to joining NASA, Latimer was on active duty with the U.S. Air Force. She has accumulated more than 5,000 hours of military and civilian flight experience in 30 aircraft. Latimer's first association with NASA was while attending graduate school at George Washington University, Washington, D.C. Her studies included work with the Joint Institute for the Advancement of Flight Sciences at NASA's Langley Research Center, Hampton, Va. She flew an Air Force C-17 during a 2005 NASA study to reduce aircraft noise. A team of California Polytechnic State University students and Northrop Grumman personnel were stationed on Rogers Dry Lake located at Edwards Air Force Base, Calif., to record the noise footprint of the aircraft as it made various landing approaches to Edwards' runway. Latimer completed undergraduate pilot training at Reese Air Force Base, Texas, in 1990. She remained at Reese as a T-38 instructor pilot until 1993. She was assigned as a C-141 aircraft commander at McCord Air Force Base, Tacoma, Wash., until 1996. Latimer graduated from the U.S. Air Force Test Pilot School at Edwards in Class 96B. She served as a C-17 and C-141 experimental test pilot at Edwards until 2000. She then became the chief of the Performance Branch and a T-38 instructor pilot at The Air Force Test Pilot School. She returned to McCord in 2002, where she was a C-17 aircraft commander and the operations officer for the 62nd Operations Support Squadron. In 2004, Latimer became the commander of Edwards' 418th Flight Test Squadron and director of the Global Reach Combined Test Force. Following that assignment, she deployed to Iraq as an advisor to the Iraqi Air Force. Her last active duty tour was as an instructor a

Field Testing of a Wet FGD Additive for Enhanced Mercury Control - Task 3 Full-scale Test Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gary Blythe

2007-05-01

This Topical Report summarizes progress on Cooperative Agreement DE-FC26-04NT42309, 'Field Testing of a Wet FGD Additive'. The objective of the project is to demonstrate the use of a flue gas desulfurization (FGD) additive, Degussa Corporation's TMT-15, to prevent the reemission of elemental mercury (Hg{sup 0}) in flue gas exiting wet FGD systems on coal-fired boilers. Furthermore, the project intends to demonstrate whether the additive can be used to precipitate most of the mercury (Hg) removed in the wet FGD system as a fine TMT salt that can be separated from the FGD liquor and bulk solid byproducts for separate disposal.more » The project is conducting pilot- and full-scale tests of the TMT-15 additive in wet FGD absorbers. The tests are intended to determine required additive dosages to prevent Hg{sup 0} reemissions and to separate mercury from the normal FGD byproducts for three coal types: Texas lignite/Power River Basin (PRB) coal blend, high-sulfur Eastern bituminous coal, and low-sulfur Eastern bituminous coal. The project team consists of URS Group, Inc., EPRI, TXU Generation Company LP, Southern Company, and Degussa Corporation. TXU Generation has provided the Texas lignite/PRB cofired test site for pilot FGD tests, Monticello Steam Electric Station Unit 3. Southern Company is providing the low-sulfur Eastern bituminous coal host site for wet scrubbing tests, as well as the pilot- and full-scale jet bubbling reactor (JBR) FGD systems to be tested. IPL, an AES company, provided the high-sulfur Eastern bituminous coal full-scale FGD test site and cost sharing. Degussa Corporation is providing the TMT-15 additive and technical support to the test program as cost sharing. The project is being conducted in six tasks. Of the six project tasks, Task 1 involves project planning and Task 6 involves management and reporting. The other four tasks involve field testing on FGD systems, either at pilot or full scale. The four tasks include: Task 2 - Pilot Additive Testing in Texas Lignite Flue Gas; Task 3 - Full-scale FGD Additive Testing in High-sulfur Eastern Bituminous Flue Gas; Task 4 - Pilot Wet Scrubber Additive Tests at Plant Yates; and Task 5 - Full-scale Additive Tests at Plant Yates. The pilot-scale tests were completed in 2005 and have been previously reported. This topical report presents the results from the Task 3 full-scale additive tests, conducted at IPL's Petersburg Station Unit 2. The Task 5 full-scale additive tests will be conducted later in calendar year 2007.« less

Development of a Web-based question database for students' self-assessment.

PubMed

Hammoud, Maya M; Barclay, Mel L

2002-09-01

Computer-based testing (CBT) for the purpose of the national licensure examination has increased interest among medical students in this modality of testing. The advent of Web-based question-delivery systems for self-assessment and learning has made it possible for students to practice this technology and participate in self-directed learning. Test Pilot(TM) is a Web-based program that provides a fast and easy tool for the development and deployment of online testing. Our objectives for introducing the program were to (1) develop a large database of questions for students' practice and self-assessment; (2) include multimedia tools such as illustrations and short videos to enhance learning; (3) provide a feedback tool for clerkship and site directors regarding student performance; and (4) evaluate this tool in terms of students' frequency of use, students' satisfaction, and its potential effectiveness in enhancing learning. The Obstetrics and Gynecology clerkship at the University of Michigan is held at four different sites. In the past, students have been provided with access to floppy disks that contain about 500 self-assessment questions. These questions have been reformatted, updated, and transferred to Test Pilot. Visual illustrations have been added to the questions along with more varied formats, including extended matching, fill-in, and essay questions. The questions are divided into ten-question quizzes. The students get immediate feedback after answering each question and a summary of performance at the end of each quiz. Security, access, and analysis are facilitated because the questions and responses are stored centrally. In addition, Test Pilot captures information regarding individual and collective students' performances. At the end of the rotation, students fill out a form evaluating the Test Pilot program and comparing it with the quiz disks. In addition, we are collecting data regarding the actual use of Test Pilot, which will be compared with the students' surveys and final exam scores. Test Pilot has many benefits, including access control, immediate feedback, automated scoring, interactive learning, and data analysis. The enhancement of material permitted by a Web-based system increases the depth and variety of the learning experience by adding perceptual dimensions. Test Pilot also provides the clerkship director with the capability to obtain improved measurements of student performance and captures the student's self-learning and testing process. It can potentially identify weaknesses or inconsistencies across the different sites and recognize students who may need additional help early in the rotation. Over a one-year period, most students have switched from the quiz disks to Test Pilot. The students reported satisfaction with the Web-based format and found it user friendly. They especially liked the immediate feedback. The students have requested more questions and multimedia options be added. We plan to continue the development and assessment of this learning tool.

Vessel-associated stem cells from skeletal muscle: From biology to future uses in cell therapy

PubMed Central

Sancricca, Cristina; Mirabella, Massimiliano; Gliubizzi, Carla; Broccolini, Aldobrando; Gidaro, Teresa; Morosetti, Roberta

2010-01-01

Over the last years, the existence of different stem cells with myogenic potential has been widely investigated. Besides the classical skeletal muscle progenitors represented by satellite cells, numerous multipotent and embryologically unrelated progenitors with a potential role in muscle differentiation and repair have been identified. In order to conceive a therapeutic approach for degenerative muscle disorders, it is of primary importance to identify an ideal stem cell endowed with all the features for a possible use in vivo. Among all emerging populations, vessel-associated stem cells are a novel and promising class of multipotent progenitors of mesodermal origin and with high myogenic potential which seem to best fit all the requirements for a possible cell therapy. In vitro and in vivo studies have already tested the effectiveness and safety of vessel-associated stem cells in animal models. This leads to the concrete possibility in the future to start pilot human clinical trials, hopefully opening the way to a turning point in the treatment of genetic and acquired muscle disorders. PMID:21607121

Assessment of simulation fidelity using measurements of piloting technique in flight. II

NASA Technical Reports Server (NTRS)

Ferguson, S. W.; Clement, W. F.; Hoh, R. H.; Cleveland, W. B.

1985-01-01

Two components of the Vertical Motion Simulator (presently being used to assess the fidelity of UH-60A simulation) are evaluated: (1) the dash/quickstop Nap-of-the-earth (NOE) piloting task, and (2) the bop-up task. Data from these two flight test experiments are presented which provide information on the effect of reduced visual field of view, variation in scene content and texture, and the affect of pure time delay in the closed-loop pilot response. In comparison with task performance results obtained in flight tests, the results from the simulation indicate that the pilot's NOE task performance in the simulator is significantly degraded.

Navigation experience and mental representations of the environment: do pilots build better cognitive maps?

PubMed

Sutton, Jennifer E; Buset, Melanie; Keller, Mikayla

2014-01-01

A number of careers involve tasks that place demands on spatial cognition, but it is still unclear how and whether skills acquired in such applied experiences transfer to other spatial tasks. The current study investigated the association between pilot training and the ability to form a mental survey representation, or cognitive map, of a novel, ground-based, virtual environment. Undergraduate students who were engaged in general aviation pilot training and controls matched to the pilots on gender and video game usage freely explored a virtual town. Subsequently, participants performed a direction estimation task that tested the accuracy of their cognitive map representation of the town. In addition, participants completed the Object Perspective Test and rated their spatial abilities. Pilots were significantly more accurate than controls at estimating directions but did not differ from controls on the Object Perspective Test. Locations in the town were visited at a similar rate by the two groups, indicating that controls' relatively lower accuracy was not due to failure to fully explore the town. Pilots' superior performance is likely due to better online cognitive processing during exploration, suggesting the spatial updating they engage in during flight transfers to a non-aviation context.

Navigation Experience and Mental Representations of the Environment: Do Pilots Build Better Cognitive Maps?

PubMed Central

Sutton, Jennifer E.; Buset, Melanie; Keller, Mikayla

2014-01-01

A number of careers involve tasks that place demands on spatial cognition, but it is still unclear how and whether skills acquired in such applied experiences transfer to other spatial tasks. The current study investigated the association between pilot training and the ability to form a mental survey representation, or cognitive map, of a novel, ground-based, virtual environment. Undergraduate students who were engaged in general aviation pilot training and controls matched to the pilots on gender and video game usage freely explored a virtual town. Subsequently, participants performed a direction estimation task that tested the accuracy of their cognitive map representation of the town. In addition, participants completed the Object Perspective Test and rated their spatial abilities. Pilots were significantly more accurate than controls at estimating directions but did not differ from controls on the Object Perspective Test. Locations in the town were visited at a similar rate by the two groups, indicating that controls' relatively lower accuracy was not due to failure to fully explore the town. Pilots' superior performance is likely due to better online cognitive processing during exploration, suggesting the spatial updating they engage in during flight transfers to a non-aviation context. PMID:24603608

The DAST-1 remotely piloted research vehicle development and initial flight testing

NASA Technical Reports Server (NTRS)

Kotsabasis, A.

1981-01-01

The development and initial flight testing of the DAST (drones for aerodynamic and structural testing) remotely piloted research vehicle, fitted with the first aeroelastic research wing ARW-I are presented. The ARW-I is a swept supercritical wing, designed to exhibit flutter within the vehicle's flight envelope. An active flutter suppression system (FSS) designed to increase the ARW-I flutter boundary speed by 20 percent is described. The development of the FSS was based on prediction techniques of structural and unsteady aerodynamic characteristics. A description of the supporting ground facilities and aircraft systems involved in the remotely piloted research vehicle (RPRV) flight test technique is given. The design, specification, and testing of the remotely augmented vehicle system are presented. A summary of the preflight and flight test procedures associated with the RPRV operation is given. An evaluation of the blue streak test flight and the first and second ARW-I test flights is presented.

Operating experiences with electrolytes containing lithium fluoride

NASA Astrophysics Data System (ADS)

Wendt, Günther

1971-12-01

Additions of lithium salts to the cryolite bath of horizontal stud Soederberg cells have been tested for the last 10 years, at first with some pilot cells and then with full potlines of 35 and 40 kamp cells. Under special conditions, economic benefits result. Voltage, power, anode paste, and fluorine electrolyte consumptions are lower; current efficiency is increased. On the other hand, more attention is necessary in pot operations because the alumina solubility is reduced. The addition of a readily soluble alumina is advantageous. The LiF-content in the electrolyte seems to be limited according to type of pot to 2 to 5 pct. Type and method of adding the lithium salts affect the consumption of lithium salts. The influence of supplementary additions, as CaF2, KF, MgF2, and NaCl, will be discussed.

Suggestions for Job and Curriculum Ladders in Health Center Ambulatory Care: A Pilot Test of the Health Services Mobility Study Methodology.

ERIC Educational Resources Information Center

Gilpatrick, Eleanor

This report contains the results of a pilot test which represents the first complete field test of methodological work begun in October 1967 under a Federal grant for the purpose of job analysis in the health services. This 4-year Health Services Mobility Study permitted basic research, field testing, practical application, and policy involvement…

Development and Validation of a Web-Based Survey on the Use of Personal Communication Devices by Hospital Registered Nurses: Pilot Study

PubMed Central

LeVasseur, Sandra A; Li, Dongmei

2013-01-01

Background The use of personal communication devices (such as basic cell phones, enhanced cell phones or smartphones, and tablet computers) in hospital units has risen dramatically in recent years. The use of these devices for personal and professional activities can be beneficial, but also has the potential to negatively affect patient care, as clinicians may become distracted by these devices. Objective No validated questionnaire examining the impact of the use of these devices on patient care exists; thus, we aim to develop and validate an online questionnaire for surveying the views of registered nurses with experience of working in hospitals regarding the impact of the use of personal communication devices on hospital units. Methods A 50-item, four-domain questionnaire on the views of registered nursing staff regarding the impact of personal communication devices on hospital units was developed based on a literature review and interviews with such nurses. A repeated measures pilot study was conducted to examine the psychometrics of a survey questionnaire and the feasibility of conducting a larger study. Psychometric testing of the questionnaire included examining internal consistency reliability and test-retest reliability in a sample of 50 registered nurses. Results The response rate for the repeated measures was 30%. Cronbach coefficient alpha was used to examine the internal consistency and reliability, and in three of the four question groups (utilization, impact, and opinions), the correlation was observed to be very high. This suggests that the questions were measuring a single underlying theme. The Cronbach alpha value for the questions in the performance group, describing the use of personal communication devices while working, was lower than those for the other question groups. These values may be an indication that the assumptions underlying the Cronbach alpha calculation may have been violated for this group of questions. A Spearman rho correlation was used to determine the test-retest reliability. There was a strong test-retest reliability between the two tests for the majority of the questions. The average test-retest percent of agreement for the Likert scale responses was 74% (range 43-100%). Accounting for responses within the 1 SD range on the Likert scale increased the agreement to 96% (range 87-100%). Missing data were in the range of 0 to 7%. Conclusions The psychometrics of the questionnaire showed good to fair levels of internal consistency and test-retest reliability. The pilot study demonstrated that our questionnaire may be useful in exploring registered nurses’ perceptions of the impact of personal electronic devices on hospital units in a larger study. PMID:24280660

A Pilot Intervention to Increase Women’s Coping Skills in Family Reintegration after Deployment in Combat Areas

DTIC Science & Technology

2013-01-01

Document specific challenges and facilitators involved in family reintegration for women and 2) Develop and pilot test a telephone- delivered coping...for women in the National Guard and Reserves who have recently returned from deployment, and 2) Develop and pilot test a telephone-delivered coping...as a framework for the development of an economical and viable coping intervention to facilitate family relationships during reintegration? 4. How

Communicating Instantaneous Air Quality Data: Pilot Project

EPA Pesticide Factsheets

Communicating Instantaneous Air Quality Data: Pilot ProjectEPA is launching a pilot project to test a new tool for making instantaneous outdoor air quality data useful for the public. The new “sensor scale” is designed to be used with sensors

Predicting General Aviation Accident Frequency From Pilot Total Flight Hours

DOT National Transportation Integrated Search

2012-10-01

Craig (2001) hypothesized a killing zonea range of pilot total flight hours (TFH) from about 50-350, over : which general aviation (GA) pilots are at greatest risk. The current work tested a number of candidate modeling : functions on eight ...

X-15 test pilots - in a lighter mood

NASA Technical Reports Server (NTRS)

1966-01-01

The X-15 pilots clown around in front of the #2 aircraft.From left to right: USAF Capt. Joseph Engle, USAF Maj. Robert Rushworth, NASA test pilot John 'Jack' McKay, USAF Maj. William 'Pete' Knight, NASA test pilot Milton Thompson, and NASA test pilot William Dana. First flown in 1959 from the NASA High Speed Flight Station (later renamed the Dryden Flight Research Center), the rocket powered X-15 was developed to provide data on aerodynamics, structures, flight controls and the physiological aspects of high speed, high altitude flight. Three were built by North American Aviation for NASA and the U.S. Air Force. They made a total of 199 flights during a highly successful research program lasting almost ten years, following which its speed and altitude records for winged aircraft remained unbroken until the Space Shuttle first returned from earth orbit in 1981. The X-15's main rocket engine provided thrust for the first 80 to 120 seconds of a 10 to 11 minute flight; the aircraft then glided to a 200 mph landing. The X-15 reached altitudes of 354,200 feet (67.08 miles) and a speed of 4,520 mph (Mach 6.7).

Frank Batteas

NASA Technical Reports Server (NTRS)

1999-01-01

Frank Batteas is a research test pilot in the Flight Crew Branch of NASA's Dryden Flight Research Center, Edwards, California. He is currently a project pilot for the F/A-18 and C-17 flight research projects. In addition, his flying duties include operation of the DC-8 Flying Laboratory in the Airborne Science program, and piloting the B-52B launch aircraft, the King Air, and the T-34C support aircraft. Batteas has accumulated more than 4,700 hours of military and civilian flight experience in more than 40 different aircraft types. Batteas came to NASA Dryden in April 1998, following a career in the U.S. Air Force. His last assignment was at Wright-Patterson Air Force Base, Dayton, Ohio, where Lieutenant Colonel Batteas led the B-2 Systems Test and Evaluation efforts for a two-year period. Batteas graduated from Class 88A of the Air Force Test Pilot School, Edwards Air Force Base, California, in December 1988. He served more than five years as a test pilot for the Air Force's newest airlifter, the C-17, involved in nearly every phase of testing from flutter and high angle-of-attack tests to airdrop and air refueling envelope expansion. In the process, he achieved several C-17 firsts including the first day and night aerial refuelings, the first flight over the North Pole, and a payload-to-altitude world aviation record. As a KC-135 test pilot, he also was involved in aerial refueling certification tests on a number of other Air Force aircraft. Batteas received his commission as a second lieutenant in the U. S. Air Force through the Reserve Officer Training Corps and served initially as an engineer working on the Peacekeeper and Minuteman missile programs at the Ballistic Missile Office, Norton Air Force Base, Calif. After attending pilot training at Williams Air Force Base, Phoenix, Ariz., he flew operational flights in the KC-135 tanker aircraft and then was assigned to research flying at the 4950th Test Wing, Wright-Patterson. He flew extensively modified C-135 and C-18 aircraft. In addition, he was project manager and research pilot for aurora borealis studies on the Airborne Ionospheric Observatory. Batteas earned a bachelor of science degree in nuclear engineering from Rensselaer Polytechnic Institute, Troy, N.Y., in 1977 and was awarded master of science degrees in systems management from the University of Southern California in 1980 and in mechanical engineering from California State University Fresno in 1991.

Glider Pilot Written Test Guide: Private and Commercial.

ERIC Educational Resources Information Center

Federal Aviation Administration (DOT), Washington, DC. Flight Standards Service.

The intent of this guide is to define the scope and narrow the field of study as far as possible to the aeronautical knowledge required for qualifying for the private or commercial pilot (glider) certificate. Briefly summarized are type of test items used, hints for taking the test, and certificate requirements. The study outline is the basic…

Pilot testing of SHRP 2 reliability data and analytical products: Minnesota.

DOT National Transportation Integrated Search

2015-01-01

The Minnesota pilot site has undertaken an effort to test data and analytical tools developed through the Strategic Highway Research Program (SHRP) 2 Reliability focus area. The purpose of these tools is to facilitate the improvement of travel time r...

Online pre-race education improves test scores for volunteers at a marathon.

PubMed

Maxwell, Shane; Renier, Colleen; Sikka, Robby; Widstrom, Luke; Paulson, William; Christensen, Trent; Olson, David; Nelson, Benjamin

2017-09-01

This study examined whether an online course would lead to increased knowledge about the medical issues volunteers encounter during a marathon. Health care professionals who volunteered to provide medical coverage for an annual marathon were eligible for the study. Demographic information about medical volunteers including profession, specialty, education level and number of marathons they had volunteered for was collected. A 15-question test about the most commonly encountered medical issues was created by the authors and administered before and after the volunteers took the online educational course and compared to a pilot study the previous year. Seventy-four subjects completed the pre-test. Those who participated in the pilot study last year (N = 15) had pre-test scores that were an average of 2.4 points higher than those who did not (mean ranks: pilot study = 51.6 vs. non-pilot = 33.9, p = 0.004). Of the 74 subjects who completed the pre-test, 54 also completed the post-test. The overall post-pre mean score difference was 3.8 ± 2.7 (t = 10.5 df = 53 p < 0.001). While subjects with all levels of volunteer experience demonstrated improvement, only change among first time marathon volunteers was significantly different from the others. Subjects reporting all degree/certification levels demonstrated improvement, but no difference in improvement was found between degree/certification levels. In this follow-up to the previous year's pilot study, online education demonstrated a long-term (one-year) increase in test scores. Testing also continued to show short-term improvement in post-course test scores, compared to pre-course test scores. In general, marathon medical volunteers who had no volunteer experience demonstrated greater improvement than those who had prior volunteer experience.

14 CFR 61.413 - What are the privileges of my flight instructor certificate with a sport pilot rating?

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false What are the privileges of my flight instructor certificate with a sport pilot rating? 61.413 Section 61.413 Aeronautics and Space FEDERAL... flight instructor certificate with a sport pilot rating; (h) A knowledge test for a sport pilot...

Safety pilot model deployment : lessons learned and recommendations for future connected vehicle activities.

DOT National Transportation Integrated Search

2015-09-01

The Connected Vehicle Safety Pilot was a research program that demonstrated the readiness of DSRC-based connected vehicle safety applications for nationwide deployment. The vision of the Connected Vehicle Safety Pilot Program was to test connected ve...

Oregon department of transportation small business group twice-monthly payments pilot project : summary report.

DOT National Transportation Integrated Search

2008-07-01

Oregon Department of Transportation (ODOT) recently completed a pilot study on small business payment practices. In the study, three pilot projects were tested where payments to small business contractors were changed from a monthly payment to twice-...

Development and pilot testing of daily Interactive Voice Response (IVR) calls to support antiretroviral adherence in India: A mixed-methods pilot study

PubMed Central

Swendeman, Dallas; Jana, Smarajit; Ray, Protim; Mindry, Deborah; Das, Madhushree; Bhakta, Bhumi

2015-01-01

This two-phase pilot study aimed to design, pilot, and refine an automated Interactive Voice Response (IVR) intervention to support antiretroviral adherence for people living with HIV (PLH), in Kolkata, India. Mixed-methods formative research included a community advisory board (CAB) for IVR message development, one-month pre-post pilot, post-pilot focus groups, and further message development. Two IVR calls are made daily, timed to patients’ dosing schedules, with brief messages (<1-minute) on strategies for self-management of three domains: medical (adherence, symptoms, co-infections), mental health (social support, stress, positive cognitions), and nutrition and hygiene (per PLH preferences). Three ART appointment reminders are also sent each month. One-month pilot results (n=46, 80% women, 60% sex workers) found significant increases in self-reported ART adherence, both within past three days (p=0.05) and time since missed last dose (p=0.015). Depression was common. Messaging content and assessment domains were expanded for testing in a randomized trial is currently underway. PMID:25638037

Development and Pilot Testing of Daily Interactive Voice Response (IVR) Calls to Support Antiretroviral Adherence in India: A Mixed-Methods Pilot Study.

PubMed

Swendeman, Dallas; Jana, Smarajit; Ray, Protim; Mindry, Deborah; Das, Madhushree; Bhakta, Bhumi

2015-06-01

This two-phase pilot study aimed to design, pilot, and refine an automated interactive voice response (IVR) intervention to support antiretroviral adherence for people living with HIV (PLH), in Kolkata, India. Mixed-methods formative research included a community advisory board for IVR message development, 1-month pre-post pilot, post-pilot focus groups, and further message development. Two IVR calls are made daily, timed to patients' dosing schedules, with brief messages (<1-min) on strategies for self-management of three domains: medical (adherence, symptoms, co-infections), mental health (social support, stress, positive cognitions), and nutrition and hygiene (per PLH preferences). Three ART appointment reminders are also sent each month. One-month pilot results (n = 46, 80 % women, 60 % sex workers) found significant increases in self-reported ART adherence, both within past three days (p = 0.05) and time since missed last dose (p = 0.015). Depression was common. Messaging content and assessment domains were expanded for testing in a randomized trial currently underway.

The Use of Novel Therapies to Reconstitute Blood Cell Production Production and Promote Organ Performance, Using Bone Marrow Failure as Modela Model

DTIC Science & Technology

2015-10-01

reported to be on Zenpep for gastro intestinal absorption issues and there are no data on the absorption of Leucine in this setting) . There was one...gastrointestinal absorption issues. As there are no data on the absorption of Leucine in this setting , the subject was withdrawn. 19DEC2014 Subject 12-002... Leucine is one of the branched chain amino acids and has been shown to upregulate protein translation . This is a pilot study to test the feasibility of

14 CFR 135.293 - Initial and recurrent pilot testing requirements.

Code of Federal Regulations, 2011 CFR

2011-01-01

..., high altitude weather; (7) Procedures for— (i) Recognizing and avoiding severe weather situations; (ii) Escaping from severe weather situations, in case of inadvertent encounters, including low-altitude windshear (except that rotorcraft pilots are not required to be tested on escaping from low-altitude...

14 CFR 135.293 - Initial and recurrent pilot testing requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., high altitude weather; (7) Procedures for— (i) Recognizing and avoiding severe weather situations; (ii) Escaping from severe weather situations, in case of inadvertent encounters, including low-altitude windshear (except that rotorcraft pilots are not required to be tested on escaping from low-altitude...

Pilot testing of SHRP 2 reliability data and analytical products: Florida. [supporting datasets

DOT National Transportation Integrated Search

2014-01-01

SHRP 2 initiated the L38 project to pilot test products from five of the programs completed projects. The products support reliability estimation and use based on data analyses, analytical techniques, and decision-making framework. The L38 project...

Skylab 4 crew at start of high altitude chamber test at KSC

NASA Technical Reports Server (NTRS)

1973-01-01

Astronaut William R. Pogue, left, and Scientist-Astronaut Edward G. Gibson prepare to take part in the High altitude chamber test at the Kennedy Space Center (KSC). Gibson is science pilot and Pogue, pilot, for the third manned Skylab mission.

78 FR 70399 - Paperless Hazard Communications Pilot Program

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-25

..., and airplanes) and during inspection and emergency response simulations. (Note: For purposes of the pilot tests conducted under this project, ``simulation'' refers to planned exercises designed solely to... participants. The scope of the simulations will be defined by project data collection needs for testing...

NOX REMOVAL WITH COMBINED SELECTIVE CATALYTIC REDUCTION AND SELECTIVE NONCATALYTIC REDUCTION: PILOT- SCALE TEST RESULTS

EPA Science Inventory

Pilot-scale tests were conducted to develop a combined nitrogen oxide (NOx) reduction technology using both selective catalytic reduction (SCR) and selective noncatalytic reduction (SNCR). A commercially available vanadium-and titatnium-based composite honeycomb catalyst and enh...

Development and test of motivational approaches for increasing use of restraints

DOT National Transportation Integrated Search

1982-02-01

A pilot program to persuade automobile dealers and salespeople to promote safety belts at the point-of-sale was developed and tested. The pilot program included key messages: encouraging the use of safety belts shows concern for the customer's well-b...

Development of a Field-Deployable Psychomotor Vigilance Test to Monitor Helicopter Pilot Performance.

PubMed

McMahon, Terry W; Newman, David G

2016-04-01

Flying a helicopter is a complex psychomotor skill. Fatigue is a serious threat to operational safety, particularly for sustained helicopter operations involving high levels of cognitive information processing and sustained time on task. As part of ongoing research into this issue, the object of this study was to develop a field-deployable helicopter-specific psychomotor vigilance test (PVT) for the purpose of daily performance monitoring of pilots. The PVT consists of a laptop computer, a hand-operated joystick, and a set of rudder pedals. Screen-based compensatory tracking task software includes a tracking ball (operated by the joystick) which moves randomly in all directions, and a second tracking ball which moves horizontally (operated by the rudder pedals). The 5-min test requires the pilot to keep both tracking balls centered. This helicopter-specific PVT's portability and integrated data acquisition and storage system enables daily field monitoring of the performance of individual helicopter pilots. The inclusion of a simultaneous foot-operated tracking task ensures divided attention for helicopter pilots as the movement of both tracking balls requires simultaneous inputs. This PVT is quick, economical, easy to use, and specific to the operational flying task. It can be used for performance monitoring purposes, and as a general research tool for investigating the psychomotor demands of helicopter operations. While reliability and validity testing is warranted, data acquired from this test could help further our understanding of the effect of various factors (such as fatigue) on helicopter pilot performance, with the potential of contributing to helicopter operational safety.

Removal of adenovirus, calicivirus, and bacteriophages by conventional drinking water treatment.

PubMed

Abbaszadegan, Morteza; Monteiro, Patricia; Nwachuku, Nena; Alum, Absar; Ryu, Hodon

2008-02-01

This study was conducted to evaluate the removal of adenovirus, feline calicivirus (FCV), and bacteriophages MS-2, fr, PRD-1, and Phi X-174 during conventional drinking water treatment using ferric chloride as a coagulant. Adenovirus and FCV were removed to a greater extent than PRD-1 and Phi X-174, indicating that these bacteriophages may be appropriate surrogates for both adenovirus and FCV. Of the four bacteriophages studied in the pilot plant, MS-2 was removed to the greatest extent (5.1 log), followed by fr (4.9 log), PRD-1 (3.5 log), and Phi X-174 (1.3 log). The virus removal trend in the pilot-scale testing was similar to the bench-scale testing; however, the bench-scale testing seemed to provide a conservative estimate of the pilot plant performance. In the pilot-scale testing, MS-2 and fr were removed with the greatest efficiency during filtration, whereas PRD-1 and Phi X-174 showed the greatest removal during sedimentation.

[Resistivity and hemodynamic reactions of essentially healthy pilots to the passive orthostatic test].

PubMed

Bondareva, S V; Vartbaronov, R A; Ponomarenko, K V; Bagaudinov, K G; Khomenko, M N

2009-01-01

The paper analyzes the data of expert tilt testing (-80 degrees, 20 min.) of 66 essentially healthy pilots. Hemodynamic reactions were characterized based on the standard concept of functional classes (FC). Good test tolerance was recorded in 86.4% of cases among which 36.4% were referred to FC-I and 50%--to FC-II. Adequate test tolerance (FC-II) was recorded in 10.6%; reduced and poor test tolerance (FC-IV and FC-V)--in 3%. According to ECG and computerized tachooscillography, the adaptive hemodynamic reactions were optimum in pilots of group FC-I as compared with group FC-II and all the more so when compared with FC-III. The last two groups showed some objective symptoms that had not been looked for in the past (a distinct lability of blood pressure, and incomplete hypertensive and hypotensive reactions) that differentiated these groups from FC-I. Results of the analysis made it possible to put forward additional clinical functional criteria to assess tilt tolerance of pilots with different levels of functional tolerance.

Treatment of Cr(VI)-containing wastewaters with exopolysaccharide-producing cyanobacteria in pilot flow through and batch systems.

PubMed

Colica, Giovanni; Mecarozzi, Pier Cesare; De Philippis, Roberto

2010-08-01

Seven exopolysaccharide-producing cyanobacteria were tested with regard to their capability to remove Cr(VI) from the wastewater of a plating industry. The cyanobacterium which showed, under lab conditions, the most promising features with regard to both Cr(VI) removal (about 12 mg of Cr(VI) removed per gram of dry biomass) and growth characteristics (highest growth rate and simplest culture medium) was Nostoc PCC7936. Furthermore, in lab experiments, it was also found that a HCl pretreatment is essential to abate the concentration of Cr(VI) in solution and that the viability of the biomass is not necessary. Subsequently, three pilot devices were tested, one batch (a dialysis cell) and two flow-through systems (a filter press and a column filled with quartz grain). The best performances were obtained with the filter press, where it was observed a sharp decrease in the concentration of Cr(VI), partly due to the adsorption of the metal by the biomass (about 50%) and partly due to its reduction to Cr(III). The results are discussed in terms of the role played by the different components (biomass and polysaccharide) of the cyanobacterial cultures in the removal of Cr(VI).

Safety of Immunogenicity Testing of a Pilot Polysaccharide Vaccine Preparation to Pseudomonas aeruginosa.

DTIC Science & Technology

1980-09-01

Pilot Polysaccharide Vaccine Preparation to Pseudomonas Aeruginosa .°’. SafGetad uoenct Testin ofaPio.PDsa.ard e(For p ri d 16 August 1979 to 15 August...Immunogenicity Testing of a Pilot Annual Report Polysaccharide Vaccine Preparation to (16 Aug. 79 - 15 Auj. 80) Pseudomonas Aeruginosa 6. PERFORMING ORG. REPORT...qiit polysaccharide (PS) maLerial isolated from Lhe ouit e _l Aace or, cultural supernates of P. ae ruginosa (i) . in it tyl , ; I m W" "des have

Scaled Composites' Doug Shane examines the screen of his ground control station during tests in New Mexico. Shane used this configuration as the ground control station to remotely pilot the Proteus aircraft during a NASA sponsored series of tests.

NASA Image and Video Library

2002-03-13

Scaled Composites' Doug Shane examines the screen of his ground control station during tests in New Mexico. Shane used this configuration as the ground control station to remotely pilot the Proteus aircraft during a NASA sponsored series of tests.

Ion Implantation with in-situ Patterning for IBC Solar Cells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Graff, John W.

2014-10-24

Interdigitated back-side Contact (IBC) solar cells are the highest efficiency silicon solar cells currently on the market. Unfortunately the cost to produce these solar cells is also very high, due to the large number of processing steps required. Varian believes that only the combination of high efficiency and low cost can meet the stated goal of $1/Wp. The core of this program has been to develop an in-situ patterning capability for an ion implantation system capable of producing patterned doped regions for IBC solar cells. Such a patterning capable ion implanter can reduce the number of process steps required tomore » manufacture IBC cells, and therefore significantly reduce the cost. The present program was organized into three phases. Phase I was to select a patterning approach and determine the patterning requirements for IBC cells. Phase II consists of construction of a Beta ion implantation system containing in-situ patterning capability. Phase III consists of shipping and installation of the ion implant system in a customer factory where it will be tested and proven in a pilot production line.« less

Clinical outcomes of a novel therapeutic vaccine with Tax peptide-pulsed dendritic cells for adult T cell leukaemia/lymphoma in a pilot study.

PubMed

Suehiro, Youko; Hasegawa, Atsuhiko; Iino, Tadafumi; Sasada, Amane; Watanabe, Nobukazu; Matsuoka, Masao; Takamori, Ayako; Tanosaki, Ryuji; Utsunomiya, Atae; Choi, Ilseung; Fukuda, Tetsuya; Miura, Osamu; Takaishi, Shigeo; Teshima, Takanori; Akashi, Koichi; Kannagi, Mari; Uike, Naokuni; Okamura, Jun

2015-05-01

Adult T cell leukaemia/lymphoma (ATL) is a human T cell leukaemia virus type-I (HTLV-I)-infected T cell malignancy with poor prognosis. We herein developed a novel therapeutic vaccine designed to augment an HTLV-I Tax-specific cytotoxic T lymphocyte (CTL) response that has been implicated in anti-ATL effects, and conducted a pilot study to investigate its safety and efficacy. Three previously treated ATL patients, classified as intermediate- to high-risk, were subcutaneously administered with the vaccine, consisting of autologous dendritic cells (DCs) pulsed with Tax peptides corresponding to the CTL epitopes. In all patients, the performance status improved after vaccination without severe adverse events, and Tax-specific CTL responses were observed with peaks at 16-20 weeks. Two patients achieved partial remission in the first 8 weeks, one of whom later achieved complete remission, maintaining their remission status without any additional chemotherapy 24 and 19 months after vaccination, respectively. The third patient, whose tumour cells lacked the ability to express Tax at biopsy, obtained stable disease in the first 8 weeks and later developed slowly progressive disease although additional therapy was not required for 14 months. The clinical outcomes of this pilot study indicate that the Tax peptide-pulsed DC vaccine is a safe and promising immunotherapy for ATL. © 2015 John Wiley & Sons Ltd.

RP101 improves the efficacy of chemotherapy in pancreas carcinoma cell lines and pancreatic cancer patients.

PubMed

Fahrig, Rudolf; Quietzsch, Detlef; Heinrich, Jörg-Christian; Heinemann, Volker; Boeck, Stefan; Schmid, Roland M; Praha, Christian; Liebert, Andreas; Sonntag, Denise; Krupitza, Georg; Hänel, Mathias

2006-10-01

RP101 [(E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU)], which supports apoptosis and prevents the acquisition of chemoresistance, was tested in cultured human pancreatic tumor cells. RP101 downregulated uridine phosphorylase, a marker of poor prognosis, and APEX1, which is involved in DNA repair, and repressed Stat3 and its target vascular endothelial growth factor. Furthermore, RP101 activated antitumor immunity as demonstrated by enhanced cytolytic activity of NK-92 natural killer cells. This was concomitant with an enhanced expression of lymphotoxins alpha and beta, natural killer cell transcript 4, tumor necrosis factor LIGHT/TNFSF-14, and intercellular adhesion molecule-1 in pancreas carcinoma cells. These results encouraged us to investigate the effect of RP101 in pancreas cancer patients. Here, we present data from two RP101 combination therapy schemes. In a first pilot study, 13 patients in stage III and VI of the disease were treated with gemcitabine +cisplatin+RP101. RP101 co-treatment enhanced remissions, survival and time to progression. Seventy-seven percent of the patients lived or have lived longer than 1 year, and 23% have lived more than 2 years. Median survival was 447 days, time to progression 280 days and the response rate 33%. A second study with 21 patients in similar stages of disease, treated with RP101+gemcitabine alone, confirmed the results of the pilot study. Eighty-three percent of the presently evaluable patients live or lived 0.5 years or longer and 33% 1 year or longer. Considering both studies, the tumor control was 94%. The data indicate that acquisition of chemoresistance was prevented and the antitumor efficacy of standard chemotherapy was improved. To our knowledge, RP101 co-treatment is more efficient than any other regimen published.

A randomized controlled pilot study feasibility of a tablet-based guided audio-visual relaxation intervention for reducing stress and pain in adults with sickle cell disease.

PubMed

Ezenwa, Miriam O; Yao, Yingwei; Engeland, Christopher G; Molokie, Robert E; Wang, Zaijie Jim; Suarez, Marie L; Wilkie, Diana J

2016-06-01

To test feasibility of a guided audio-visual relaxation intervention protocol for reducing stress and pain in adults with sickle cell disease. Sickle cell pain is inadequately controlled using opioids, necessitating further intervention such as guided relaxation to reduce stress and pain. Attention-control, randomized clinical feasibility pilot study with repeated measures. Randomized to guided relaxation or control groups, all patients recruited between 2013-2014 during clinical visits, completed stress and pain measures via a Galaxy Internet-enabled Android tablet at the Baseline visit (pre/post intervention), 2-week posttest visit and also daily at home between the two visits. Experimental group patients were asked to use a guided relaxation intervention at the Baseline visit and at least once daily for 2 weeks. Control group patients engaged in a recorded sickle cell discussion at the Baseline visit. Data were analysed using linear regression with bootstrapping. At baseline, 27/28 of consented patients completed the study protocol. Group comparison showed that guided relaxation significantly reduced current stress and pain. At the 2-week posttest, 24/27 of patients completed the study, all of whom reported liking the study. Patients completed tablet-based measures on 71% of study days (69% in control group, 72% in experiment group). At the 2-week posttest, the experimental group had significantly lower composite pain index scores, but the two groups did not differ significantly on stress intensity. This study protocol appears feasible. The tablet-based guided relaxation intervention shows promise for reducing sickle cell pain and warrants a larger efficacy trial. The ClinicalTrials.gov Identifier is: NCT02501447. © 2016 John Wiley & Sons Ltd.

Optimization of Fit for Mass Customized Apparel Ordering Using Fit Preference and Self Measurement.

DTIC Science & Technology

2000-01-01

shorts had the highest satisfaction of fit and which short provided the optimum fit. Finally a discrepancy question form and a manual order form were...used during fit test sessions. In pilot testing manual order forms were used exclusively to record self-measurements and fit preference responses for...test participants. The website requirements were completed on site in the pilot test and manual order forms were returned to test evaluators once

Connected Vehicle Pilot Deployment Program phase I : comprehensive Pilot Deployment Plan : Tampa Hillsborough Expressway Authority (THEA) : final report.

DOT National Transportation Integrated Search

2016-07-01

The Tampa Hillsborough Expressway Authority (THEA) Connected Vehicle (CV) Pilot Deployment Program is part of a national effort to advance CV technologies by deploying, demonstrating, testing and offering lessons learned for future deployers. The THE...

The effects of enhanced hexapod motion on airline pilot recurrent training and evaluation

DOT National Transportation Integrated Search

2003-08-13

A quasi-transfer experiment tested the effect of : simulator motion on recurrent evaluation and training : of airline pilots. Two groups of twenty B747-400 pilots : were randomly assigned to a flight simulator with or : without platform motion. In th...

An investigation into pilot and system response to critical in-flight events, volume 1

NASA Technical Reports Server (NTRS)

Rockwell, T. H.; Giffin, W. C.

1981-01-01

The scope of a critical in-flight event (CIFE) with emphasis on pilot management of available resources is described. Detailed scenarios for both full mission simulation and written testing of pilot responses to CIFE's, and statistical relationships among pilot characteristics and observed responses are developed. A model developed to described pilot response to CIFE and an analysis of professional fight crews compliance with specified operating procedures and the relationships with in-flight errors are included.

Automatic Generation of Test Oracles - From Pilot Studies to Application

NASA Technical Reports Server (NTRS)

Feather, Martin S.; Smith, Ben

1998-01-01

There is a trend towards the increased use of automation in V&V. Automation can yield savings in time and effort. For critical systems, where thorough V&V is required, these savings can be substantial. We describe a progression from pilot studies to development and use of V&V automation. We used pilot studies to ascertain opportunities for, and suitability of, automating various analyses whose results would contribute to V&V. These studies culminated in the development of an automatic generator of automated test oracles. This was then applied and extended in the course of testing an Al planning system that is a key component of an autonomous spacecraft.

Personality Test Scores that Distinguish U.S. Air Force Remotely Piloted Aircraft Drone Pilot Training Candidates

DTIC Science & Technology

2014-02-18

advancement of aviation drone technology has led to significant developments and improvements in the capabilities of military remotely piloted aircraft...stress; less excitement seeking and action oriented; less assertive; more socially introverted and withdrawn; more socially compliant and...to age and educational differences. Fifth, evaluations that involve selection and assessment of pilot applicants should include collateral sources of

Remotely piloted vehicles. Citations from the International Aerospace abstracts data base

NASA Technical Reports Server (NTRS)

Mauk, S. C.

1980-01-01

These citations from the international literature cover various aspects of remotely piloted vehicles. Included are articles concerning aircraft design, flight tests, aircraft control, cost effectiveness, automatic flight control, automatic pilots, and data links. Civil aviation applications are included, although military uses of remotely piloted vehicles are stressed. This updated bibliography contains 224 citations, 43 of which are new additions to the previous edition.

ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT, REMOVAL OF ARSENIC IN DRINKING WATER: PHASE 1-ADI PILOT TEST UNIT NO. 2002-09 WITH MEDIA G2®

EPA Science Inventory

Integrity verification testing of the ADI International Inc. Pilot Test Unit No. 2002-09 with MEDIA G2® arsenic adsorption media filter system was conducted at the Hilltown Township Water and Sewer Authority (HTWSA) Well Station No. 1 in Sellersville, Pennsylvania from October 8...

Child Passenger Safety: A Pilot Test of a K-6 Curriculum.

ERIC Educational Resources Information Center

Li, Livia K.; And Others

A Car Passenger Safety Curriculum was developed for Grades K-6 and pilot tested in 10 elementary schools. Five schools served as treatment schools, five as comparison schools. The curriculum included materials at K-1, 2-3, and 4-6 grade levels. Observations were made of belt usage by students, and knowledge tests were administered to students…

A Pilot Study of a Test for Visual Recognition Memory in Adults with Moderate to Severe Intellectual Disability

ERIC Educational Resources Information Center

Pyo, Geunyeong; Ala, Tom; Kyrouac, Gregory A.; Verhulst, Steven J.

2010-01-01

Objective assessment of memory functioning is an important part of evaluation for Dementia of Alzheimer Type (DAT). The revised Picture Recognition Memory Test (r-PRMT) is a test for visual recognition memory to assess memory functioning of persons with intellectual disabilities (ID), specifically targeting moderate to severe ID. A pilot study was…

Final Report of the Panel on the Department of Defense Human Capital Strategy

DTIC Science & Technology

2008-01-01

has served as a member of the Board on Testing and Assessment of the National Research Council. Dr. Pearlman is a Fellow of the American Psychological ...22 Pilot- Test Selected Options...approaches to system operation. The aim of developing options would be to obtain evaluative feedback, such as from later pilot- testing , on the relative

Superfund Technology Evaluation Report: SITE Program Demonstration Test Shirco Pilot-Scale Infrared Incineration System at the Rose Township Demode Road Superfund Site Volume I

EPA Science Inventory

The Shirco Pilot-Scale Infrared Incineration System was evaluated during a series of seventeen test runs under varied operating conditions at the Demode Road Superfund Site located in Rose Township, Michigan. The tests sought to demonstrate the effectiveness of the unit and the t...

Resource Conservation and Recovery Act, Part B permit application [of the Waste Isolation Pilot Plant (WIPP)]. Volume 11, Chapter D, Appendix D4--Chapter D, Appendix D17: Revision 3

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-03-01

This volume contains appendices D4 through D17 which cover the following: Waste Isolation Pilot Plant site environmental report; ecological monitoring program at the Waste Isolation Pilot Plant; site characterization; regional and site geology and hydrology; general geology; dissolution features; ground water hydrology; typical carbon sorption bed efficiency; VOC monitoring plan for bin-room tests; chemical compatibility analysis of waste forms and container materials; probable maximum precipitation; WHIP supplementary roof support system room 1, panel 1; and corrosion risk assessment of the Waste Isolation Pilot Plant ``humid`` test bins.

Assessment of simulation fidelity using measurements of piloting technique in flight

NASA Technical Reports Server (NTRS)

Ferguson, S. W.; Clement, W. F.; Cleveland, W. B.; Key, D. L.

1984-01-01

The U.S. Army and NASA have undertaken the systematic validation of a ground-based piloted simulator for the UH-60A helicopter. The results of previous handling quality and task performance flight tests for this helicopter have been used as a data base for evaluating the fidelity of the present simulation, which is being conducted at the NASA Ames Research Center's Vertical Motion Simulator. Such nap-of-the-earth piloting tasks as pop-up, hover turn, dash/quick stop, sidestep, dolphin, and slalom, have been investigated. It is noted that pilot simulator performance is significantly and quantifiable degraded by comparison with flight test results for the same tasks.

Real-Time Onboard Global Nonlinear Aerodynamic Modeling from Flight Data

NASA Technical Reports Server (NTRS)

Brandon, Jay M.; Morelli, Eugene A.

2014-01-01

Flight test and modeling techniques were developed to accurately identify global nonlinear aerodynamic models onboard an aircraft. The techniques were developed and demonstrated during piloted flight testing of an Aermacchi MB-326M Impala jet aircraft. Advanced piloting techniques and nonlinear modeling techniques based on fuzzy logic and multivariate orthogonal function methods were implemented with efficient onboard calculations and flight operations to achieve real-time maneuver monitoring and analysis, and near-real-time global nonlinear aerodynamic modeling and prediction validation testing in flight. Results demonstrated that global nonlinear aerodynamic models for a large portion of the flight envelope were identified rapidly and accurately using piloted flight test maneuvers during a single flight, with the final identified and validated models available before the aircraft landed.

14 CFR 61.45 - Practical tests: Required aircraft and equipment.

Code of Federal Regulations, 2010 CFR

2010-01-01

... TRANSPORTATION (CONTINUED) AIRMEN CERTIFICATION: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS General § 61... in paragraphs (e) and (f) of this section, at least two pilot stations with adequate visibility for... applicant from performing all of the tasks required for the practical test. However, the applicant's...

PILOT PLANT TESTING OF ELEMENTAL MERCURY RE-EMISSION FROM WET SCRUBBERS

EPA Science Inventory

A pilot-scale wet lime/limestone flue gas desulfurization scrubber system was designed to conduct mercury emission control research. The first tests focused on investigating the phenomenon of Hgo re-emission from wet scrubbers with a specific objective of developing a Hgo re-emis...

UNIVERSITY OF WASHINGTON ELECTROSTATIC SCRUBBER TESTS AT A COAL-FIRED POWER PLANT

EPA Science Inventory

The report gives results of tests of a 1700 cu m/hr University of Washington Electrostatic Spray Scrubber pilot plant on a coal-fired boiler to demonstrate its effectiveness for controlling fine particle emissions. The multiple-pass, portable pilot plant combines oppositely charg...

14 CFR 135.291 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AND ON DEMAND OPERATIONS AND RULES GOVERNING PERSONS ON BOARD SUCH AIRCRAFT Crewmember Testing... checks required for pilot and flight attendant crewmembers and for the approval of check pilots in... chapter who meet the requirements of §§ 135.337 and 135.339 to conduct training, testing, and checking...

14 CFR 135.291 - Applicability.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AND ON DEMAND OPERATIONS AND RULES GOVERNING PERSONS ON BOARD SUCH AIRCRAFT Crewmember Testing... checks required for pilot and flight attendant crewmembers and for the approval of check pilots in... chapter who meet the requirements of §§ 135.337 and 135.339 to conduct training, testing, and checking...

14 CFR 135.291 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AND ON DEMAND OPERATIONS AND RULES GOVERNING PERSONS ON BOARD SUCH AIRCRAFT Crewmember Testing... checks required for pilot and flight attendant crewmembers and for the approval of check pilots in... chapter who meet the requirements of §§ 135.337 and 135.339 to conduct training, testing, and checking...

14 CFR 135.291 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AND ON DEMAND OPERATIONS AND RULES GOVERNING PERSONS ON BOARD SUCH AIRCRAFT Crewmember Testing... checks required for pilot and flight attendant crewmembers and for the approval of check pilots in... chapter who meet the requirements of §§ 135.337 and 135.339 to conduct training, testing, and checking...

14 CFR 135.291 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AND ON DEMAND OPERATIONS AND RULES GOVERNING PERSONS ON BOARD SUCH AIRCRAFT Crewmember Testing... checks required for pilot and flight attendant crewmembers and for the approval of check pilots in... chapter who meet the requirements of §§ 135.337 and 135.339 to conduct training, testing, and checking...

Field Testing of a Wet FGD Additive for Enhanced Mercury Control

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gary Blythe; MariJon Owens

2007-12-31

This document is the final report for DOE-NETL Cooperative Agreement DE-FC26-04NT42309, 'Field Testing of a Wet FGD Additive'. The objective of the project has been to demonstrate the use of two flue gas desulfurization (FGD) additives, Evonik Degussa Corporation's TMT-15 and Nalco Company's Nalco 8034, to prevent the re-emission of elemental mercury (Hg{sup 0}) in flue gas exiting wet FGD systems on coal-fired boilers. Furthermore, the project was intended to demonstrate whether such additives can be used to precipitate most of the mercury (Hg) removed in the wet FGD system as a fine salt that can be separated from themore » FGD liquor and bulk solid byproducts for separate disposal. The project involved pilot- and full-scale tests of the additives in wet FGD absorbers. The tests were intended to determine required additive dosages to prevent Hg{sup 0} re-emissions and to separate mercury from the normal FGD byproducts for three coal types: Texas lignite/Powder River Basin (PRB) coal blend, high-sulfur Eastern bituminous coal, and low-sulfur Eastern bituminous coal. The project team consists of URS Group, Inc., EPRI, Luminant Power (was TXU Generation Company LP), Southern Company, IPL (an AES company), Evonik Degussa Corporation and the Nalco Company. Luminant Power provided the Texas lignite/PRB co-fired test site for pilot FGD tests and project cost sharing. Southern Company provided the low-sulfur Eastern bituminous coal host site for wet scrubbing tests, the pilot- and full-scale jet bubbling reactor (JBR) FGD systems tested, and project cost sharing. IPL provided the high-sulfur Eastern bituminous coal full-scale FGD test site and cost sharing. Evonik Degussa Corporation provided the TMT-15 additive, and the Nalco Company provided the Nalco 8034 additive. Both companies also supplied technical support to the test program as in-kind cost sharing. The project was conducted in six tasks. Of the six tasks, Task 1 involved project planning and Task 6 involved management and reporting. The other four tasks involved field testing on FGD systems, either at pilot or full scale. These four tasks included: Task 2 - Pilot Additive Testing in Texas Lignite Flue Gas; Task 3 - Full-scale FGD Additive Testing in High-sulfur Eastern Bituminous Flue Gas; Task 4 - Pilot Wet Scrubber Additive Tests at Plant Yates; and Task 5 - Full-scale Additive Tests at Plant Yates. The pilot-scale tests were completed in 2005 and the full-scale test using high-sulfur coal was completed in 2006; only the TMT-15 additive was tested in these efforts. The Task 5 full-scale additive tests conducted at Southern Company's Plant Yates Unit 1 were completed in 2007, and both the TMT-15 and Nalco 8034 additives were tested.« less

Simulator study of conventional general aviation instrument displays in path-following tasks with emphasis on pilot-induced oscillations

NASA Technical Reports Server (NTRS)

Adams, J. J.

1980-01-01

A study of the use of conventional general aviation instruments by general aviation pilots in a six degree of freedom, fixed base simulator was conducted. The tasks performed were tracking a VOR radial and making an ILS approach to landing. A special feature of the tests was that the sensitivity of the displacement indicating instruments (the RMI, CDI, and HSI) was kept constant at values corresponding to 5 n. mi. and 1.25 n. mi. from the station. Both statistical and pilot model analyses of the data were made. The results show that performance in path following improved with increases in display sensitivity up to the highest sensitivity tested. At this maximum test sensitivity, which corresponds to the sensitivity existing at 1.25 n. mi. for the ILS glide slope transmitter, tracking accuracy was no better than it was at 5 n. mi. from the station and the pilot aircraft system exhibited a marked reduction in damping. In some cases, a pilot induced, long period unstable oscillation occurred.

Utility of an airframe referenced spatial auditory display for general aviation operations

NASA Astrophysics Data System (ADS)

Naqvi, M. Hassan; Wigdahl, Alan J.; Ranaudo, Richard J.

2009-05-01

The University of Tennessee Space Institute (UTSI) completed flight testing with an airframe-referenced localized audio cueing display. The purpose was to assess its affect on pilot performance, workload, and situational awareness in two scenarios simulating single-pilot general aviation operations under instrument meteorological conditions. Each scenario consisted of 12 test procedures conducted under simulated instrument meteorological conditions, half with the cue off, and half with the cue on. Simulated aircraft malfunctions were strategically inserted at critical times during each test procedure. Ten pilots participated in the study; half flew a moderate workload scenario consisting of point to point navigation and holding pattern operations and half flew a high workload scenario consisting of non precision approaches and missed approach procedures. Flight data consisted of aircraft and navigation state parameters, NASA Task Load Index (TLX) assessments, and post-flight questionnaires. With localized cues there was slightly better pilot technical performance, a reduction in workload, and a perceived improvement in situational awareness. Results indicate that an airframe-referenced auditory display has utility and pilot acceptance in general aviation operations.

Experimental investigation of piloted flameholders

NASA Technical Reports Server (NTRS)

Guo, C. F.; Zhang, Y. H.; Xie, Q. M.

1986-01-01

Four configurations of piloted flameholders were tested. The range of flame stabilization, flame propagation, pressure oscillation during ignition, and pressure drop of the configurations were determined. Some tests showed a very strong effect of inlet flow velocity profile and flameholder geometry on flame stabilization. These tests led to the following conclusions. (1) The use of a piloted flameholder in the turbofan augmentor may minimize the peak pressure rise during ignition. At the present experimental conditions, delta P/P asterisk over 2 is less than 10 percent; therefore, the use of a piloted flameholder is a good method to realize soft ignition. (2) The geometry of the piloted flameholder and the amount of fuel injected into the flameholder have a strong effect on the pressure oscillation during ignition of the fuel-air mixture in the secondary zone. (3) Compared with the V-gutter flameholder with holes in its wall, the V-gutter flameholder without holes not only has advantages such as simple structure and good rigidity but offers a wide combustion stability limit and a high capability of igniting the fuel-air mixture of the secondary zone.

An investigation into pilot and system response to critical in-flight events. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

Rockwell, T. H.; Griffin, W. C.

1981-01-01

Critical in-flight events (CIFE) that threaten the aircraft were studied. The scope of the CIFE was described and defined with emphasis on characterizing event development, detection and assessment; pilot information requirements, sources, acquisition, and interpretation, pilot response options, decision processed, and decision implementation and event outcome. Detailed scenarios were developed for use in simulators and paper and pencil testing for developing relationships between pilot performance and background information as well as for an analysis of pilot reaction decision and feedback processes. Statistical relationships among pilot characteristics and observed responses to CIFE's were developed.

Closed-loop, pilot/vehicle analysis of the approach and landing task

NASA Technical Reports Server (NTRS)

Schmidt, D. K.; Anderson, M. R.

1985-01-01

Optimal-control-theoretic modeling and frequency-domain analysis is the methodology proposed to evaluate analytically the handling qualities of higher-order manually controlled dynamic systems. Fundamental to the methodology is evaluating the interplay between pilot workload and closed-loop pilot/vehicle performance and stability robustness. The model-based metric for pilot workload is the required pilot phase compensation. Pilot/vehicle performance and loop stability is then evaluated using frequency-domain techniques. When these techniques were applied to the flight-test data for thirty-two highly-augmented fighter configurations, strong correlation was obtained between the analytical and experimental results.

Drugs and alcohol in civil aviation accident pilot fatalities from 2004-2008.

DOT National Transportation Integrated Search

2011-09-01

The FAA Office of Aerospace Medicine sets medical standards needed to protect the public and pilots from death : or injury due to incapacitation of the pilot. As a part of this process, toxicology testing is performed by the FAA : on almost every pil...

E-21539

NASA Image and Video Library

1970-06-18

The four principal HL-10 pilots are seen here with the lifting body aircraft. They are, left to right; Air Force Major Jerauld R. Gentry, Air Force test pilot Peter Hoag, and NASA pilots John A. Manke and Bill Dana. All are wearing the pressure suits needed for flying above 50,000 feet.

An ultra scale-down approach to study the interaction of fermentation, homogenization, and centrifugation for antibody fragment recovery from rec E. coli.

PubMed

Li, Qiang; Mannall, Gareth J; Ali, Shaukat; Hoare, Mike

2013-08-01

Escherichia coli is frequently used as a microbial host to express recombinant proteins but it lacks the ability to secrete proteins into medium. One option for protein release is to use high-pressure homogenization followed by a centrifugation step to remove cell debris. While this does not give selective release of proteins in the periplasmic space, it does provide a robust process. An ultra scale-down (USD) approach based on focused acoustics is described to study rec E. coli cell disruption by high-pressure homogenization for recovery of an antibody fragment (Fab') and the impact of fermentation harvest time. This approach is followed by microwell-based USD centrifugation to study the removal of the resultant cell debris. Successful verification of this USD approach is achieved using pilot scale high-pressure homogenization and pilot scale, continuous flow, disc stack centrifugation comparing performance parameters such as the fraction of Fab' release, cell debris size distribution and the carryover of cell debris fine particles in the supernatant. The integration of fermentation and primary recovery stages is examined using USD monitoring of different phases of cell growth. Increasing susceptibility of the cells to disruption is observed with time following induction. For a given recovery process this results in a higher fraction of product release and a greater proportion of fine cell debris particles that are difficult to remove by centrifugation. Such observations are confirmed at pilot scale. Copyright © 2013 Wiley Periodicals, Inc.

Cellular Components, Including Stem-Like Cells, of Preterm Mother's Mature Milk as Compared with Those in Her Colostrum: A Pilot Study.

PubMed

Kaingade, Pankaj; Somasundaram, Indumathi; Sharma, Akshita; Patel, Darshan; Marappagounder, Dhanasekaran

2017-09-01

Whether the preterm mothers' mature milk retains the same cellular components as those in colostrum including stem-like cell, cell adhesion molecules, and immune cells. A total of five preterm mothers were recruited for the study having an average age of 30.2 years and gestational age of 29.8 weeks from the Pristine Women's Hospital, Kolhapur. Colostrum milk was collected within 2-5 days and matured milk was collected 20-30 days after delivery from the same mothers. Integral cellular components of 22 markers including stem cells, immune cells, and cell adhesion molecules were measured using flowcytometry. Preterm mature milk was found to possess higher expressions of hematopoietic stem cells, mesenchymal stem-like cells, immune cells, few cell adhesion molecules, and side population cells than colostrum. The increased level of these different cell components in mature milk may be important in the long-term preterm baby's health growth. Further similar research in a larger population of various gestational ages and lactation stages of preterm mothers is warranted to support these pilot findings.

The Differential Effect of Sustained Operations on Psychomotor Skills of Helicopter Pilots.

PubMed

McMahon, Terry W; Newman, David G

2018-06-01

Flying a helicopter is a complex psychomotor skill requiring constant control inputs from pilots. A deterioration in psychomotor performance of a helicopter pilot may be detrimental to operational safety. The aim of this study was to test the hypothesis that psychomotor performance deteriorates over time during sustained operations and that the effect is more pronounced in the feet than the hands. The subjects were helicopter pilots conducting sustained multicrew offshore flight operations in a demanding environment. The remote flight operations involved constant workload in hot environmental conditions with complex operational tasking. Over a period of 6 d 10 helicopter pilots were tested. At the completion of daily flying duties, a helicopter-specific screen-based compensatory tracking task measuring tracking accuracy (over a 5-min period) tested both hands and feet. Data were compared over time and tested for statistical significance for both deterioration and differential effect. A statistically significant deterioration of psychomotor performance was evident in the pilots over time for both hands and feet. There was also a statistically significant differential effect between the hands and the feet in terms of tracking accuracy. The hands recorded a 22.6% decrease in tracking accuracy, while the feet recorded a 39.9% decrease in tracking accuracy. The differential effect may be due to prioritization of limb movement by the motor cortex due to factors such as workload-induced cognitive fatigue. This may result in a greater reduction in performance in the feet than the hands, posing a significant risk to operational safety.McMahon TW, Newman DG. The differential effect of sustained operations on psychomotor skills of helicopter pilots. Aerosp Med Hum Perform. 2018; 89(6):496-502.

Autoantibodies to nervous system-specific proteins are elevated in sera of flight crew members: biomarkers for nervous system injury.

PubMed

Abou-Donia, Mohamed B; Abou-Donia, Martha M; ElMasry, Eman M; Monro, Jean A; Mulder, Michel F A

2013-01-01

This descriptive study reports the results of assays performed to detect circulating autoantibodies in a panel of 7 proteins associated with the nervous system (NS) in sera of 12 healthy controls and a group of 34 flight crew members including both pilots and attendants who experienced adverse effects after exposure to air emissions sourced to the ventilation system in their aircrafts and subsequently sought medical attention. The proteins selected represent various types of proteins present in nerve cells that are affected by neuronal degeneration. In the sera samples from flight crew members and healthy controls, immunoglobin (IgG) was measured using Western blotting against neurofilament triplet proteins (NFP), tubulin, microtubule-associated tau proteins (tau), microtubule-associated protein-2 (MAP-2), myelin basic protein (MBP), glial fibrillary acidic protein (GFAP), and glial S100B protein. Significant elevation in levels of circulating IgG-class autoantibodies in flight crew members was found. A symptom-free pilot was sampled before symptoms and then again afterward. This pilot developed clinical problems after flying for 45 h in 10 d. Significant increases in autoantibodies were noted to most of the tested proteins in the serum of this pilot after exposure to air emissions. The levels of autoantibodies rose with worsening of his condition compared to the serum sample collected prior to exposure. After cessation of flying for a year, this pilot's clinical condition improved, and eventually he recovered and his serum autoantibodies against nervous system proteins decreased. The case study with this pilot demonstrates a temporal relationship between exposure to air emissions, clinical condition, and level of serum autoantibodies to nervous system-specific proteins. Overall, these results suggest the possible development of neuronal injury and gliosis in flight crew members anecdotally exposed to cabin air emissions containing organophosphates. Thus, increased circulating serum autoantibodies resulting from neuronal damage may be used as biomarkers for chemical-induced CNS injury.

14 CFR 141.5 - Requirements for a pilot school certificate.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Requirements for a pilot school certificate. 141.5 Section 141.5 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... and recommended at least 10 different people for a knowledge test or a practical test, or any...

SHIRCO PILOT-SCALE INFRARED INCINERATION SYSTEM AT THE ROSE TOWNSHIP DEMODE ROAD SUPERFUND SITE

EPA Science Inventory

Under the Superfund Innovative Technology Evaluation or SITE Program, an evaluation was made of the Shirco Pilot-Scale Infrared Incineration System during 17 separate test runs under varying operating conditions. The tests were conducted at the Demode Road Superfund site in Ros...

Minorities and Women in Educational Research: Progress Toward Equality. Final Report.

ERIC Educational Resources Information Center

American Educational Research Association, Washington, DC.

This report evaluates a project to pilot-test workshop materials designed to facilitate increased participation of women and minorities in educational research and development. The pilot test involved three NIE/AERA sponsored workshops organized in conjunction with the 1980 annual meeting of the American Educational Research Association. The…

78 FR 30899 - Agency Information Collection Activities; Comment Request; NCES Cognitive, Pilot, and Field Test...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-23

...; Comment Request; NCES Cognitive, Pilot, and Field Test Studies System AGENCY: Institute of Education... in response to this notice will be considered public records. Title of Collection: NCES Cognitive... with levels of incentives for various types of survey operations, focus groups, cognitive laboratory...

Evaluation Report for the Occupational Exploration Program. Pilot Test 1975.

ERIC Educational Resources Information Center

Lave, Janice; And Others

Pilot testing was conducted on parts of the Occupational Exploration Program (OEP), a classroom program designed to enhance the career awareness and career understandings of seventh and eighth grade students through simulations, games, and small group and individualized activities. The Introduction to Occupational Exploration unit and three…

Design and Testing of CPAS Main Deployment Bag Energy Modulator

NASA Technical Reports Server (NTRS)

Mollmann, Catherine

2017-01-01

During the developmental testing program for CPAS (Capsule Parachute Assembly System), the parachute system for the NASA Orion Crew Module, simulation revealed that high loads may be experienced by the pilot risers during the most devere deployment conditions. As the role of the pilot parachutes is to deploy the main parachutes, these high loads introduced the possibility of main deployment failure. In order to mitigate these high loads, a set of energy modulators was incorporated between the pilot riser and the main deployment bag. An extensive developmental program was implemented to ensure the adequacy of these energy modulators. After initial design comparisons, the energy modulator design was validated through slow-speed joint tests as well as through high-speed bungee tests. This paper documents the design, development, and results of multiple tests completed on the final design.

Fighter agility metrics, research, and test

NASA Technical Reports Server (NTRS)

Liefer, Randall K.; Valasek, John; Eggold, David P.

1990-01-01

Proposed new metrics to assess fighter aircraft agility are collected and analyzed. A framework for classification of these new agility metrics is developed and applied. A completed set of transient agility metrics is evaluated with a high fidelity, nonlinear F-18 simulation provided by the NASA Dryden Flight Research Center. Test techniques and data reduction methods are proposed. A method of providing cuing information to the pilot during flight test is discussed. The sensitivity of longitudinal and lateral agility metrics to deviations from the pilot cues is studied in detail. The metrics are shown to be largely insensitive to reasonable deviations from the nominal test pilot commands. Instrumentation required to quantify agility via flight test is also considered. With one exception, each of the proposed new metrics may be measured with instrumentation currently available. Simulation documentation and user instructions are provided in an appendix.

TASK 2: QUENCH ZONE SIMULATION

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fusselman, Steve

Aerojet Rocketdyne (AR) has developed an innovative gasifier concept incorporating advanced technologies in ultra-dense phase dry feed system, rapid mix injector, and advanced component cooling to significantly improve gasifier performance, life, and cost compared to commercially available state-of-the-art systems. A key feature of the AR gasifier design is the transition from the gasifier outlet into the quench zone, where the raw syngas is cooled to ~ 400°C by injection and vaporization of atomized water. Earlier pilot plant testing revealed a propensity for the original gasifier outlet design to accumulate slag in the outlet, leading to erratic syngas flow from themore » outlet. Subsequent design modifications successfully resolved this issue in the pilot plant gasifier. In order to gain greater insight into the physical phenomena occurring within this zone, AR developed a cold flow simulation apparatus with Coanda Research & Development with a high degree of similitude to hot fire conditions with the pilot scale gasifier design, and capable of accommodating a scaled-down quench zone for a demonstration-scale gasifier. The objective of this task was to validate similitude of the cold flow simulation model by comparison of pilot-scale outlet design performance, and to assess demonstration scale gasifier design feasibility from testing of a scaled-down outlet design. Test results did exhibit a strong correspondence with the two pilot scale outlet designs, indicating credible similitude for the cold flow simulation device. Testing of the scaled-down outlet revealed important considerations in the design and operation of the demonstration scale gasifier, in particular pertaining to the relative momentum between the downcoming raw syngas and the sprayed quench water and associated impacts on flow patterns within the quench zone. This report describes key findings from the test program, including assessment of pilot plant configuration simulations relative to actual results on the pilot plant gasifier and demonstration plant design recommendations, based on cold flow simulation results.« less

Virus removal retention challenge tests performed at lab scale and pilot scale during operation of membrane units.

PubMed

Humbert, H; Machinal, C; Labaye, Ivan; Schrotter, J C

2011-01-01

The determination of the virus retention capabilities of UF units during operation is essential for the operators of drinking water treatment facilities in order to guarantee an efficient and stable removal of viruses through time. In previous studies, an effective method (MS2-phage challenge tests) was developed by the Water Research Center of Veolia Environnement for the measurement of the virus retention rates (Log Removal Rate, LRV) of commercially available hollow fiber membranes at lab scale. In the present work, the protocol for monitoring membrane performance was transferred from lab scale to pilot scale. Membrane performances were evaluated during pilot trial and compared to the results obtained at lab scale with fibers taken from the pilot plant modules. PFU culture method was compared to RT-PCR method for the calculation of LRV in both cases. Preliminary tests at lab scale showed that both methods can be used interchangeably. For tests conducted on virgin membrane, a good consistency was observed between lab and pilot scale results with the two analytical methods used. This work intends to show that a reliable determination of the membranes performances based on RT-PCR analytical method can be achieved during the operation of the UF units.

Comparison of cyclic fatigue resistance and bending properties of two reciprocating nickel-titanium glide path files.

PubMed

Özyürek, T; Uslu, G; Gündoğar, M; Yılmaz, K; Grande, N M; Plotino, G

2018-02-25

To compare the cyclic fatigue resistance and bending properties of R-Pilot and WaveOne Gold (WOG) Glider files, at intracanal temperature (35°C). Forty R-Pilot and 40 WOG Glider files were subjected to a cyclic fatigue resistance test (n = 20), calculating the time to fracture (TTF) in an artificial stainless steel canal. The length of the fractured file tips (FL) was also measured. The fracture surface of fragments was examined with a scanning electron microscope, and the cross-sectional area of the fractured surfaces was measured. Flexibility of the tested files (n = 20) was determined using 45° bending test. Data were analysed statistically using the Mann-Whitney U-test at 5% significance level. Time to fracture was significantly higher in the R-Pilot group compared to the WOG Glider (P < 0.05). There was no significant difference between groups for fracture length. The bending resistance of R-Pilot files was significantly greater than WOG Glider files (P < 0.05). A significant greater cyclic fatigue resistance was observed for R-Pilot files compared to WOG Glider instruments, although the bending resistance of WOG Glider files was lower. © 2018 International Endodontic Journal. Published by John Wiley & Sons Ltd.

The Development of a Cell-Assembly for the Treatment of Irradiated Fuels on a Semi-Industrial Scale; ETUDE CONCERNANT LA REALISATION D'UN ENSEMBLE DE CELLULES DESTINEES A DES TRAITEMENTS DE COMBUSTIBLES IRRADIES A L'ECHELLE SEMI-INDUSTRIELLE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Faugeras, P.; Couture, J.; Lefort, G.

1961-01-01

The main studies and experiments involved in the development of a cell- assembly for the treatment of irradiated fuels on a semi-industrial scale are described. It must be possible to modify or transform each of these cells without interrupting the rest of the pilot. A full-scale prototype cell ( 3 x 4 x 6 m) was built with an alpha k-protection independent of the gamma - protection. It features all the main characteristics: tightness to gamma losses, dense glass lighting, and ventilation. This cell has made possible trials on transfer, remote-controls and teledismantling, as well as the development of newmore » methods of rapidly connecting hydraulic circuits. The final form is given of the cells selected for the pilot. (auth)« less

Feasibility of Turing-Style Tests for Autonomous Aerial Vehicle "Intelligence"

NASA Technical Reports Server (NTRS)

Young, Larry A.

2007-01-01

A new approach is suggested to define and evaluate key metrics as to autonomous aerial vehicle performance. This approach entails the conceptual definition of a "Turing Test" for UAVs. Such a "UAV Turing test" would be conducted by means of mission simulations and/or tailored flight demonstrations of vehicles under the guidance of their autonomous system software. These autonomous vehicle mission simulations and flight demonstrations would also have to be benchmarked against missions "flown" with pilots/human-operators in the loop. In turn, scoring criteria for such testing could be based upon both quantitative mission success metrics (unique to each mission) and by turning to analog "handling quality" metrics similar to the well-known Cooper-Harper pilot ratings used for manned aircraft. Autonomous aerial vehicles would be considered to have successfully passed this "UAV Turing Test" if the aggregate mission success metrics and handling qualities for the autonomous aerial vehicle matched or exceeded the equivalent metrics for missions conducted with pilots/human-operators in the loop. Alternatively, an independent, knowledgeable observer could provide the "UAV Turing Test" ratings of whether a vehicle is autonomous or "piloted." This observer ideally would, in the more sophisticated mission simulations, also have the enhanced capability of being able to override the scripted mission scenario and instigate failure modes and change of flight profile/plans. If a majority of mission tasks are rated as "piloted" by the observer, when in reality the vehicle/simulation is fully- or semi- autonomously controlled, then the vehicle/simulation "passes" the "UAV Turing Test." In this regards, this second "UAV Turing Test" approach is more consistent with Turing s original "imitation game" proposal. The overall feasibility, and important considerations and limitations, of such an approach for judging/evaluating autonomous aerial vehicle "intelligence" will be discussed from a theoretical perspective.

Methodological approaches to conducting pilot and proof tests on reverse-osmosis systems: Results of comparative studies

NASA Astrophysics Data System (ADS)

Panteleev, A. A.; Bobinkin, V. V.; Larionov, S. Yu.; Ryabchikov, B. E.; Smirnov, V. B.; Shapovalov, D. A.

2017-10-01

When designing large-scale water-treatment plants based on reverse-osmosis systems, it is proposed to conduct experimental-industrial or pilot tests for validated simulation of the operation of the equipment. It is shown that such tests allow establishing efficient operating conditions and characteristics of the plant under design. It is proposed to conduct pilot tests of the reverse-osmosis systems on pilot membrane plants (PMPs) and test membrane plants (TMPs). The results of a comparative experimental study of pilot and test membrane plants are exemplified by simulating the operating parameters of the membrane elements of an industrial plant. It is concluded that the reliability of the data obtained on the TMP may not be sufficient to design industrial water-treatment plants, while the PMPs are capable of providing reliable data that can be used for full-scale simulation of the operation of industrial reverse-osmosis systems. The test membrane plants allow simulation of the operating conditions of individual industrial plant systems; therefore, potential areas of their application are shown. A method for numerical calculation and experimental determination of the true selectivity and the salt passage are proposed. An expression has been derived that describes the functional dependence between the observed and true salt passage. The results of the experiments conducted on a test membrane plant to determine the true value of the salt passage of a reverse-osmosis membrane are exemplified by magnesium sulfate solution at different initial operating parameters. It is shown that the initial content of a particular solution component has a significant effect on the change in the true salt passage of the membrane.

Objective Versus Subjective Military Pilot Selection Methods in the United States of America

DTIC Science & Technology

2015-12-14

a computerized test designed to assess pilot skills by measuring spatial orientation and psychomotor skills and multitasking . The second is the...AFRL-SA-WP-SR-2015-0028 Objective Versus Subjective Military Pilot Selection Methods in the United States of America Joe...September 2014 4. TITLE AND SUBTITLE Objective Versus Subjective Military Pilot Selection Methods in the United States of America 5a. CONTRACT

Quality of reporting of pilot and feasibility cluster randomised trials: a systematic review

PubMed Central

Chan, Claire L; Leyrat, Clémence; Eldridge, Sandra M

2017-01-01

Objectives To systematically review the quality of reporting of pilot and feasibility of cluster randomised trials (CRTs). In particular, to assess (1) the number of pilot CRTs conducted between 1 January 2011 and 31 December 2014, (2) whether objectives and methods are appropriate and (3) reporting quality. Methods We searched PubMed (2011–2014) for CRTs with ‘pilot’ or ‘feasibility’ in the title or abstract; that were assessing some element of feasibility and showing evidence the study was in preparation for a main effectiveness/efficacy trial. Quality assessment criteria were based on the Consolidated Standards of Reporting Trials (CONSORT) extensions for pilot trials and CRTs. Results Eighteen pilot CRTs were identified. Forty-four per cent did not have feasibility as their primary objective, and many (50%) performed formal hypothesis testing for effectiveness/efficacy despite being underpowered. Most (83%) included ‘pilot’ or ‘feasibility’ in the title, and discussed implications for progression from the pilot to the future definitive trial (89%), but fewer reported reasons for the randomised pilot trial (39%), sample size rationale (44%) or progression criteria (17%). Most defined the cluster (100%), and number of clusters randomised (94%), but few reported how the cluster design affected sample size (17%), whether consent was sought from clusters (11%), or who enrolled clusters (17%). Conclusions That only 18 pilot CRTs were identified necessitates increased awareness of the importance of conducting and publishing pilot CRTs and improved reporting. Pilot CRTs should primarily be assessing feasibility, avoiding formal hypothesis testing for effectiveness/efficacy and reporting reasons for the pilot, sample size rationale and progression criteria, as well as enrolment of clusters, and how the cluster design affects design aspects. We recommend adherence to the CONSORT extensions for pilot trials and CRTs. PMID:29122791

ECN-2409

NASA Image and Video Library

1970-06-17

Not every moment of a test pilot's day is serious business. In a moment of levity, NASA pilots Bill Dana (left) and John A. Manke try to drag Air Force test pilot Peter Hoag away from the HL-10 lifting body while Air Force Major Jerauld R. Gentry helps from the cockpit. These four men were the principal pilots for the HL-10 program. This was not the only prank involving the HL-10 and its pilots. Once "Captain Midnight" (Gentry) and the "Midnight Skulkers" sneaked into the NASA hangar and put "U.S. Air Force" on the aircraft using stick-on letters. Later, while Gentry was making a lifting-body flight, his 1954 Ford was "borrowed" from the parking lot, painted with yellow-green zinc-chromate primer, and decorated with large stick-on flowers about one foot in diameter. After Gentry returned from the flight, he was surprised to see what had happened to his car.

EFFECT OF PILOT HOLE TAPPING ON PULLOUT STRENGTH AND INSERTION TORQUE OF DUAL CORE PEDICLE SCREWS.

PubMed

Rosa, Rodrigo César; Silva, Patrícia; Falcai, Maurício José; Shimano, Antônio Carlos; Defino, Helton Luiz Aparecido

2010-01-01

To evaluate the influence of pilot hole tapping on pullout resistance and insertion torque of pedicle screws with a conical core. Mechanical tests using a universal testing machine were performed on pedicle screws with a conical core that were inserted into pedicles in the fifth lumbar vertebra of calves. The insertion torque was measured using a torque meter with a capacity of 10 Nm, which was considered to be the highest torque value. The pilot holes were prepared using a probe of external diameter 3.8 mm and tapping of the same dimensions and thread characteristics as the screw. Decreased insertion torque and pullout resistance were observed in the group with prior tapping of the pilot hole. Pilot hole tapping reduced the insertion torque and pullout resistance of pedicle screws with a conical core that had been inserted into the pedicle of the fifth lumbar vertebra of calves.

[Personnel with poor vision at fighter pilot school].

PubMed

Corbé, C; Menu, J P

1997-10-01

The piloting of fighting aircraft, the navigation of space-shuttle, the piloting of an helicopter in tactical flight at an altitude of 50 metres require the use of all sensorial, ocular, vestibular, proprioceptive ... sensors. So, the selection and the follow-up of these aerial engines' pilots need a very complete study of medical parameters, in particular sensorial and notably visual system. The doctors and the expert researchers in Aeronautical and spatial Medicine of the Army Health Department, which have in charge the medical supervision of flight crew, should study, create, and improve tests of visual sensorial exploration developed from fundamental and applied research. These authenticated tests with military pilots were applied in ophthalmology for the estimation of normal and deficient vision. A proposition to change norms of World Health Organisation applied to the vision has been following these to low visual persons was equally introduced.

A Study of Longitudinal Control Problems at Low and Negative Damping and Stability with Emphasis on Effects of Motion Cues

NASA Technical Reports Server (NTRS)

Sadoff, Melvin; McFadden, Norman M.; Heinle, Donovan R.

1961-01-01

As part of a general investigation to determine the effects of simulator motions on pilot opinion and task performance over a wide range of vehicle longitudinal dynamics, a cooperative NASA-AMAL program was conducted on the centrifuge at Johnsville, Pennsylvania. The test parameters and measurements for this program duplicated those of earlier studies made at Ames Research Center with a variable-stability airplane and with a pitch-roll chair flight simulator. Particular emphasis was placed on the minimum basic damping and stability the pilots would accept and on the minimum dynamics they considered controllable in the event of stability-augmentation system failure. Results of the centrifuge-simulator program indicated that small positive damping was required by the pilots over most of the frequency range covered for configurations rated acceptable for emergency conditions only (e.g., failure of a pitch damper). It was shown that the pilot's tolerance for unstable dynamics was dependent primarily on the value of damping. For configurations rated acceptable for emergency operation only, the allowable instability and damping corresponded to a divergence time to double amplitude of about 1 second. Comparisons were made of centrifuge, pitch-chair and fixed-cockpit simulator tests with flight tests. Pilot ratings indicated that the effects of incomplete or spurious motion cues provided by these three modes of simulation were important only for high-frequency, lightly damped dynamics or unstable, moderately damped dynamics. The pitch- chair simulation, which provided accurate angular-acceleration cues to the pilot, compared most favorably with flight. For the centrifuge simulation, which furnished accurate normal accelerations but spurious pitching and longitudinal accelerations, there was a deterioration of pilots' opinion relative to flight results. Results of simulator studies with an analog pilot replacing the human pilot illustrated the adaptive capability of human pilots in coping with the wide range of vehicle dynamics and the control problems covered in this study. It was shown that pilot-response characteristics, deduced by the analog-pilot method, could be related to pilot opinion. Possible application of these results for predicting flight-control problems was illustrated by means of an example control-problem analysis. The results of a brief evaluation of a pencil-type side-arm controller in the centrifuge showed a considerable improvement in the pilots' ability to cope with high-frequency, low-damping dynamics, compared to results obtained with the center stick. This improvement with the pencil controller was attributed primarily to a marked reduction in the adverse effects of large and exaggerated pitching and longitudinal accelerations on pilot control precision.

76 FR 12367 - Proposed Information Collection; Visibility Valuation Survey Pilot Study

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-07

... Survey Pilot Study AGENCY: National Park Service, U.S. Department of the Interior. ACTION: Notice... Code of Federal Regulations). Updated estimates of visibility benefits are required because the studies... a pilot study to test the survey instrument and implementation procedures prior to the full survey...

Identification of pilot-vehicle dynamics from simulation and flight test

NASA Technical Reports Server (NTRS)

Hess, Ronald A.

1990-01-01

The paper discusses an identification problem in which a basic feedback control structure, or pilot control strategy, is hypothesized. Identification algorithms are employed to determine the particular form of pilot equalization in each feedback loop. It was found that both frequency- and time-domain identification techniques provide useful information.

78 FR 6074 - Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-29

... pilot and perform the training; (2) the training practices and programs that are designed to enhance the..., before pilot trainers for initial the field test. training is held. (2) Evaluation Surveys from... reactions to the manager training toolkit trainings held after they have used by pilot it to train case...

76 FR 63988 - Pilot Project on NAFTA Trucking Provisions; Pre-Authorization Safety Audits

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-14

...-0097] Pilot Project on NAFTA Trucking Provisions; Pre-Authorization Safety Audits AGENCY: Federal Motor... public comment on data and information concerning the Pre-Authorization Safety Audits (PASAs) for two motor carriers that applied to participate in the Agency's long-haul pilot program to test and...

Physiologic and anti-G suit performance data from YF-16 flight tests

NASA Technical Reports Server (NTRS)

Gillingham, K. K.; Winter, W. R.

1976-01-01

Biomedical data were collected during high-G portions of 11 YF-16 test flights. Test pilots monitored revealed increased respiratory rate and volume, decreased tidal volume, and increased heart rate at higher G levels, with one pilot exhibiting various cardiac arrhythmias. Anti-G suit inflation and pressurization lags varied inversely with G-onset rate, and suit pressurization slope was near the design value.

Forecasting Demand for Civilian Pilots: A Cost Savings Approach to Managing Air Force Pilot Resources

DTIC Science & Technology

2007-03-01

terror attacks led people to believe that flying was unsafe. The Breusch - Pagan /Cook-Weisberg test for heteroskedasticity was performed to find...would yield an increase of 13.8 million revenue passenger miles. As with the previous model, the Breusch - Pagan /Cook-Weisberg test for...Appendix A. Data Set of Variables Studied ............................................................ 31 Appendix B. Stationarity Tests

Test Market Media Relations as a Pilot Test Component in a Nationwide Class Action Settlement Distribution.

ERIC Educational Resources Information Center

Pellecchia, Michael

Results of a pilot test for a public relations campaign to assist in the distribution of funds from the settlement of a nationwide class action suit brought by tenants against the Department of Housing and Urban Development (HUD) are presented in this report. The first chapter presents the background of the case, noting that tenants of Section 236…

Prediction of pilot opinion ratings using an optimal pilot model. [of aircraft handling qualities in multiaxis tasks

NASA Technical Reports Server (NTRS)

Hess, R. A.

1977-01-01

A brief review of some of the more pertinent applications of analytical pilot models to the prediction of aircraft handling qualities is undertaken. The relative ease with which multiloop piloting tasks can be modeled via the optimal control formulation makes the use of optimal pilot models particularly attractive for handling qualities research. To this end, a rating hypothesis is introduced which relates the numerical pilot opinion rating assigned to a particular vehicle and task to the numerical value of the index of performance resulting from an optimal pilot modeling procedure as applied to that vehicle and task. This hypothesis is tested using data from piloted simulations and is shown to be reasonable. An example concerning a helicopter landing approach is introduced to outline the predictive capability of the rating hypothesis in multiaxis piloting tasks.

Enhancing HIV Testing and Treatment among Men Who Have Sex with Men in China: A Pilot Model with Two-Rapid Tests, Single Blood Draw Session, and Intensified Case Management in Six Cities in 2013.

PubMed

Zhang, Dapeng; Lu, Hongyan; Zhuang, Minghua; Wu, Guohui; Yan, Hongjing; Xu, Jun; Wei, Xiaoli; Li, Chengmei; Meng, Sining; Fu, Xiaojing; Qi, Jinlei; Wang, Peng; Luo, Mei; Dai, Min; Yip, Ray; Sun, Jiangping; Wu, Zunyou

2016-01-01

To explore models to improve HIV testing, linkage to care and treatment among men who have sex with men (MSM) in cooperation with community-based organizations (CBOs) in China. We introduced a new model for HIV testing services targeting MSM in six cities in 2013.These models introduced provision of rapid HIV testing by CBO staff and streamlined processes for HIV screening, confirmation of initial reactive screening results, and linkage to care among diagnosed people. We monitored attrition along each step of the continuum of care from screening to treatment and compared program performance between 2012 and 2013. According to the providers of two rapid tests (HIV screening), four different services delivery models were examined in 2013: Model A = first screen at CDC, second at CDC (Model A = CDC+CDC), Model B = first and second screens at CBOs (Model B = CBO+CBO), Model C = first screen at CBO, second at Hospital (Model C = CBO+Hosp), and Model D = first screen at CBO, second at CDC (Model D = CBO+CDC). Logistic regressions were performed to assess advantages of different screening models of case finding and case management. Compared to 2012, the number of HIV screening tests performed for MSM increased 35.8% in 2013 (72,577 in 2013 vs. 53,455 in 2012). We observed a 5.6% increase in proportion of cases screened reactive receiving HIV confirmatory tests (93.9% in 2013 vs. 89.2% in 2012, χ2 = 48.52, p<0.001) and 65% reduction in loss to CD4 cell count tests (15% in 2013 vs. 43% in 2012, χ2 = 628.85, p<0.001). Regarding linkage to care and treatment, the 2013 pilot showed that the Model D had the highest rate of loss between screening reactive and confirmatory test among the four models, with 18.1% fewer receiving a second screening test and a further 5.9% loss among those receiving HIV confirmatory tests. The Model B and the Model C showed lower losses (0.8% and 1.3%) for newly diagnosed HIV positives receiving CD4 cell count tests, and higher rates of HIV positives referred to designated ART hospitals (88.0% and 93.3%) than the Model A and Model D (4.6% and 5.7% for CD4 cell count test, and 68.9% and 64.4% for referring to designated ART hospitals). The proportion of cases where the screening test was reactive that were commenced on ART was highest in Model C; 52.8% of cases commenced on ART compared to 38.9%, 34.2% and 21.1% in Models A, B and D respectively. Using Model A as a reference group, the multivariate logistic regression results also showed the advantages of Models B, C and D, which increased CD4 cell count test, referral to designated ART hospitals and initiation of ART, when controlling for program city and other factors. This study has demonstrated that involvement of CBOs in HIV rapid testing provision, streamlining testing and care procedures and early hospital case management can improve testing, linkage to, and retention in care and treatment among MSM in China.

Gene Expression Profile Analysis as a Prognostic Indicator of Normal Tissue Response to Simulated Space Radiations

NASA Technical Reports Server (NTRS)

Story, Michael; Stivers, David N.

2004-01-01

This project was funded as a pilot project to determine the feasibility of using gene expression profiles to characterize the response of human cells to exposure to particulate radiations such as those encountered in the spaceflight environment. We proposed to use microarray technology to examine the gene expression patterns of a bank of well-characterized human fibroblast cell cultures. These fibroblast cultures were derived from breast or head and neck cancer patients who exhibited normal, minimal, or severe normal tissue reactions following low LET radiation exposure via radiotherapy. Furthermore, determination of SF2 values from fibroblasts cultured from these individuals were predictive of risk for severe late reactions. We hypothesized that by determining the expression of thousands of genes we could identify gene expression patterns that reflect how normal tissues respond to high Z and energy (HZE) particles, that is, that there are molecular signatures for HZE exposures. We also hypothesized that individuals who are intrinsically radiosensitive may elicit a unique response. Because this was funded as a pilot project we focused our initial studies on logistics and appropriate experimental design, and then to test our hypothesis that there is a unique molecular response to specific particles, in this case C and Fe, for primary human skin fibroblasts.

Hematopoietic Cell Transplant and Use of Massage for Improved Symptom Management: Results from a Pilot Randomized Control Trial

PubMed Central

Mehling, Wolf E.; Lown, E. Anne; Dvorak, Christopher C.; Cowan, Morton J.; Horn, Biljana N.; Dunn, Elizabeth A.; Acree, Michael; Abrams, Donald I.; Hecht, Frederick M.

2012-01-01

Background. Pediatric hematopoietic cell transplant (HCT) is a lifesaving treatment that often results in physical and psychological discomfort. An acupressure-massage intervention may improve symptom management in this setting. Methods. This randomized controlled pilot trial compared a combined massage-acupressure intervention to usual care. Children were offered three practitioner-provided sessions per week throughout hospitalization. Parents were trained to provide additional acupressure as needed. Symptoms were assessed using nurses' reports and two questionnaires, the behavioral affective and somatic experiences scale and the Peds quality of life cancer module. Results. We enrolled 23 children, ages 5 to 18. Children receiving the intervention reported fewer days of mucositis (Hedges' g effect size ES = 0.63), lower overall symptom burden (ES = 0.26), feeling less tired and run-down (ES = 0.86), having fewer moderate/severe symptoms of pain, nausea, and fatigue (ES = 0.62), and less pain (ES = 0.42). The intervention group showed trends toward increasing contentness/serenity (ES = +0.50) and decreasing depression (ES = −0.45), but not decreased anxiety (ES = +0.42). Differences were not statistically significant. Discussion. Feasibility of studying massage-acupressure was established in children undergoing HCT. Larger studies are needed to test the efficacy of such interventions in reducing HCT-associated symptoms in children. PMID:22454665

Portable Weather Applications for General Aviation Pilots.

PubMed

Ahlstrom, Ulf; Ohneiser, Oliver; Caddigan, Eamon

2016-09-01

The objective of this study was to examine the potential benefits and impact on pilot behavior from the use of portable weather applications. Seventy general aviation (GA) pilots participated in the study. Each pilot was randomly assigned to an experimental or a control group and flew a simulated single-engine GA aircraft, initially under visual meteorological conditions (VMC). The experimental group was equipped with a portable weather application during flight. We recorded measures for weather situation awareness (WSA), decision making, cognitive engagement, and distance from the aircraft to hazardous weather. We found positive effects from the use of the portable weather application, with an increased WSA for the experimental group, which resulted in credibly larger route deviations and credibly greater distances to hazardous weather (≥30 dBZ cells) compared with the control group. Nevertheless, both groups flew less than 20 statute miles from hazardous weather cells, thus failing to follow current weather-avoidance guidelines. We also found a credibly higher cognitive engagement (prefrontal oxygenation levels) for the experimental group, possibly reflecting increased flight planning and decision making on the part of the pilots. Overall, the study outcome supports our hypothesis that portable weather displays can be used without degrading pilot performance on safety-related flight tasks, actions, and decisions as measured within the constraints of the present study. However, it also shows that an increased WSA does not automatically translate to enhanced flight behavior. The study outcome contributes to our knowledge of the effect of portable weather applications on pilot behavior and decision making. © 2016, Human Factors and Ergonomics Society.

Individual differences and subjective workload assessment - Comparing pilots to nonpilots

NASA Technical Reports Server (NTRS)

Vidulich, Michael A.; Pandit, Parimal

1987-01-01

Results by two groups of subjects, pilots and nonpilots, for two subjective workload assessment techniques (the SWAT and NASA-TLX tests) intended to evaluate individual differences in the perception and reporting of subjective workload are compared with results obtained for several traditional personality tests. The personality tests were found to discriminate between the groups while the workload tests did not. It is concluded that although the workload tests may provide useful information with respect to the interaction between tasks and personality, they are not effective as pure tests of individual differences.

Is red cell distribution width a novel biomarker of breast cancer activity? Data from a pilot study.

PubMed

Seretis, Charalampos; Seretis, Fotios; Lagoudianakis, Emmanouil; Gemenetzis, George; Salemis, Nikolaos S

2013-04-01

Red cell distribution width (RDW) is a parameter of the standard full blood count tests, measuring the size variability of erythrocytes. Recently, its elevation has been proven to reliably reflect the extent systematic inflammation, mainly in cardiometabolic diseases. Up to date, its association with solid malignancies has been scarcely investigated. We performed a retrospective study, in order to examine if RDW values comparing elevation is correlated with the histopathological parameters of breast cancer (tumor size, grade, lymphatic spread, overexpression of hormonal receptors and HER2 protein), as well as to assess the existence of any differences in RDW comparing two age-matched groups of patients with benign and malignant breast lesions respectively. RDW was significantly higher in patients with breast cancer, when compared to the enrolled patients with fibroadenomas. Moreover, in the breast cancer group, RDW elevation was significantly correlated with larger primary tumors, higher number of infiltrated axillary lymph nodes and HER2 overexpression, while it was inversely associated with the tumor grade. Our pilot study demonstrated tha Red cell distribution width may be a novel biomarker of the activity of breast cancer. Although our preliminary findings need to be evaluated by studies with larger samples of patients, based on commonly accepted pathophysiological principles, we presume that they will be applicable not only in breast cancer, but also in other types of solid cancers, providing a simple and cost-effective biomarker of cancer surveillance.

Is Red Cell Distribution Width a Novel Biomarker of Breast Cancer Activity? Data From a Pilot Study

PubMed Central

Seretis, Charalampos; Seretis, Fotios; Lagoudianakis, Emmanouil; Gemenetzis, George; Salemis, Nikolaos S.

2013-01-01

Background Red cell distribution width (RDW) is a parameter of the standard full blood count tests, measuring the size variability of erythrocytes. Recently, its elevation has been proven to reliably reflect the extent systematic inflammation, mainly in cardiometabolic diseases. Up to date, its association with solid malignancies has been scarcely investigated. Methods We performed a retrospective study, in order to examine if RDW values comparing elevation is correlated with the histopathological parameters of breast cancer (tumor size, grade, lymphatic spread, overexpression of hormonal receptors and HER2 protein), as well as to assess the existence of any differences in RDW comparing two age-matched groups of patients with benign and malignant breast lesions respectively. Results RDW was significantly higher in patients with breast cancer, when compared to the enrolled patients with fibroadenomas. Moreover, in the breast cancer group, RDW elevation was significantly correlated with larger primary tumors, higher number of infiltrated axillary lymph nodes and HER2 overexpression, while it was inversely associated with the tumor grade. Conclusions Our pilot study demonstrated tha Red cell distribution width may be a novel biomarker of the activity of breast cancer. Although our preliminary findings need to be evaluated by studies with larger samples of patients, based on commonly accepted pathophysiological principles, we presume that they will be applicable not only in breast cancer, but also in other types of solid cancers, providing a simple and cost-effective biomarker of cancer surveillance. PMID:23518817

Early diagnosis of severe combined immunodeficiency (SCID) in Turkey: a pilot study.

PubMed

Can, Ceren; Hamilçıkan, Şahin; Can, Emrah

2017-08-29

Severe combined immunodeficiency (SCID) is a neonatal emergency. As the T-cell receptor excision circles (TREC) test is not cost effective for neonatal screening of SCID in developing countries, this pilot study's objective aimed at identifying preliminary data to enable SCID identification in the general population. This observational study was performed in Bagcılar Training and Research Hospital, Istanbul, Turkey. Cord-blood complete blood count (CBC) was recorded in all neonates included in the study. Absolute lymphopenia was considered in cord-blood samples if the absolute lymphocyte count was less than 2500/mm 3 . A control blood count was performed 1-month later for cases with detected lymphopenia. A total of 2945 term neonates were included in the study. Absolute lymphopenia was found in nine (0.3%) neonates, while 2936 (99.7%) had an absolute lymphocytic count above 2.5 × 10 3 /mm 3 . The mean counts of red blood cells (RBC), hemoglobin (HGB), hematocrit (HCT), platelets (PLT), and monocytes in the lymphopenia group were not found to significantly differ from the non-lymphopenia group. However, there were significantly lower mean white blood cell (WBC), lymphocyte, and neutrophil counts between the groups (p < .05). Absolute lymphopenia detected using CBC analysis is a simple, easier, more non-invasive, and cheaper method than the TREC method for detection of SCID neonates, and this method may prove to be a useful alternative, especially in developing countries.

An automated laboratory-scale methodology for the generation of sheared mammalian cell culture samples.

PubMed

Joseph, Adrian; Goldrick, Stephen; Mollet, Michael; Turner, Richard; Bender, Jean; Gruber, David; Farid, Suzanne S; Titchener-Hooker, Nigel

2017-05-01

Continuous disk-stack centrifugation is typically used for the removal of cells and cellular debris from mammalian cell culture broths at manufacturing-scale. The use of scale-down methods to characterise disk-stack centrifugation performance enables substantial reductions in material requirements and allows a much wider design space to be tested than is currently possible at pilot-scale. The process of scaling down centrifugation has historically been challenging due to the difficulties in mimicking the Energy Dissipation Rates (EDRs) in typical machines. This paper describes an alternative and easy-to-assemble automated capillary-based methodology to generate levels of EDRs consistent with those found in a continuous disk-stack centrifuge. Variations in EDR were achieved through changes in capillary internal diameter and the flow rate of operation through the capillary. The EDRs found to match the levels of shear in the feed zone of a pilot-scale centrifuge using the experimental method developed in this paper (2.4×10 5 W/Kg) are consistent with those obtained through previously published computational fluid dynamic (CFD) studies (2.0×10 5 W/Kg). Furthermore, this methodology can be incorporated into existing scale-down methods to model the process performance of continuous disk-stack centrifuges. This was demonstrated through the characterisation of culture hold time, culture temperature and EDRs on centrate quality. © 2017 The Authors. Biotechnology Journal published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Relationship between Recent Flight Experience and Pilot Error General Aviation Accidents

NASA Astrophysics Data System (ADS)

Nilsson, Sarah J.

Aviation insurance agents and fixed-base operation (FBO) owners use recent flight experience, as implied by the 90-day rule, to measure pilot proficiency in physical airplane skills, and to assess the likelihood of a pilot error accident. The generally accepted premise is that more experience in a recent timeframe predicts less of a propensity for an accident, all other factors excluded. Some of these aviation industry stakeholders measure pilot proficiency solely by using time flown within the past 90, 60, or even 30 days, not accounting for extensive research showing aeronautical decision-making and situational awareness training decrease the likelihood of a pilot error accident. In an effort to reduce the pilot error accident rate, the Federal Aviation Administration (FAA) has seen the need to shift pilot training emphasis from proficiency in physical airplane skills to aeronautical decision-making and situational awareness skills. However, current pilot training standards still focus more on the former than on the latter. The relationship between pilot error accidents and recent flight experience implied by the FAA's 90-day rule has not been rigorously assessed using empirical data. The intent of this research was to relate recent flight experience, in terms of time flown in the past 90 days, to pilot error accidents. A quantitative ex post facto approach, focusing on private pilots of single-engine general aviation (GA) fixed-wing aircraft, was used to analyze National Transportation Safety Board (NTSB) accident investigation archival data. The data were analyzed using t-tests and binary logistic regression. T-tests between the mean number of hours of recent flight experience of tricycle gear pilots involved in pilot error accidents (TPE) and non-pilot error accidents (TNPE), t(202) = -.200, p = .842, and conventional gear pilots involved in pilot error accidents (CPE) and non-pilot error accidents (CNPE), t(111) = -.271, p = .787, indicate there is no statistically significant relationship between groups. Binary logistic regression indicate that recent flight experience does not reliably distinguish between pilot error and non-pilot error accidents for TPE/TNPE, chi2 = 0.040 (df=1, p = .841) and CPE/CNPE, chi2= 0.074 (df =1, p = .786). Future research could focus on different pilot populations, and to broaden the scope, analyze several years of data.

Teaching Cockpit Automation in the Classroom

NASA Technical Reports Server (NTRS)

Casner, Stephen M.

2003-01-01

This study explores the idea of teaching fundamental cockpit automation concepts and skills to aspiring professional pilots in a classroom setting, without the use of sophisticated aircraft or equipment simulators. Pilot participants from a local professional pilot academy completed eighteen hours of classroom instruction that placed a strong emphasis on understanding the underlying principles of cockpit automation systems and their use in a multi-crew cockpit. The instructional materials consisted solely of a single textbook. Pilots received no hands-on instruction or practice during their training. At the conclusion of the classroom instruction, pilots completed a written examination testing their mastery of what had been taught during the classroom meetings. Following the written exam, each pilot was given a check flight in a full-mission Level D simulator of a Boeing 747-400 aircraft. Pilots were given the opportunity to fly one practice leg, and were then tested on all concepts and skills covered in the class during a second leg. The results of the written exam and simulator checks strongly suggest that instruction delivered in a traditional classroom setting can lead to high levels of preparation without the need for expensive airplane or equipment simulators.

Integration of visual and motion cues for simulator requirements and ride quality investigation. [computerized simulation of aircraft landing, visual perception of aircraft pilots

NASA Technical Reports Server (NTRS)

Young, L. R.

1975-01-01

Preliminary tests and evaluation are presented of pilot performance during landing (flight paths) using computer generated images (video tapes). Psychophysiological factors affecting pilot visual perception were measured. A turning flight maneuver (pitch and roll) was specifically studied using a training device, and the scaling laws involved were determined. Also presented are medical studies (abstracts) on human response to gravity variations without visual cues, acceleration stimuli effects on the semicircular canals, and neurons affecting eye movements, and vestibular tests.

Utility of quantitative sensory testing and screening tools in identifying HIV-associated peripheral neuropathy in Western Kenya: pilot testing.

PubMed

Cettomai, Deanna; Kwasa, Judith; Kendi, Caroline; Birbeck, Gretchen L; Price, Richard W; Bukusi, Elizabeth A; Cohen, Craig R; Meyer, Ana-Claire

2010-12-08

Neuropathy is the most common neurologic complication of HIV but is widely under-diagnosed in resource-constrained settings. We aimed to identify tools that accurately distinguish individuals with moderate/severe peripheral neuropathy and can be administered by non-physician healthcare workers (HCW) in resource-constrained settings. We enrolled a convenience sample of 30 HIV-infected outpatients from a Kenyan HIV-care clinic. A HCW administered the Neuropathy Severity Score (NSS), Single Question Neuropathy Screen (Single-QNS), Subjective Peripheral Neuropathy Screen (Subjective-PNS), and Brief Peripheral Neuropathy Screen (Brief-PNS). Monofilament, graduated tuning fork, and two-point discrimination examinations were performed. Tools were validated against a neurologist's clinical assessment of moderate/severe neuropathy. The sample was 57% male, mean age 38.6 years, and mean CD4 count 324 cells/µL. Neurologist's assessment identified 20% (6/30) with moderate/severe neuropathy. Diagnostic utilities for moderate/severe neuropathy were: Single-QNS--83% sensitivity, 71% specificity; Subjective-PNS-total--83% sensitivity, 83% specificity; Subjective-PNS-max and NSS--67% sensitivity, 92% specificity; Brief-PNS--0% sensitivity, 92% specificity; monofilament--100% sensitivity, 88% specificity; graduated tuning fork--83% sensitivity, 88% specificity; two-point discrimination--75% sensitivity, 58% specificity. Pilot testing suggests Single-QNS, Subjective-PNS, and monofilament examination accurately identify HIV-infected patients with moderate/severe neuropathy and may be useful diagnostic tools in resource-constrained settings.

Pilot social feasibility study for the establishment of a public human umbilical cord blood stem cell bank in South Africa.

PubMed

Meissner-Roloff, Madelein; Young, Wendy; Rangaka, Isabella; Lombaard, Hennie; Dhai, Ames; Tsotsi, Norma; Pepper, Michael S

2012-12-01

There is a large unmet need in South Africa for bone marrow transplantation. Umbilical cord blood (UCB) is an important source of stem cells for the treatment of haematological and non-haematological diseases. Access to the two existing private umbilical cord blood stem cell banks (UCB SCBs) in South Africa is limited to individuals that can afford it, which further aggravates the ever increasing divide between families from different socio-economic classes. The problem is compounded by a severe global shortage of genetically compatible samples, representative of the South African demographics. Establishing a public human UCB SCB in South Africa would provide more South Africans with access to previously unavailable treatment in the form of affordable, genetically compatible stem cells for bone marrow transplantation. A public UCB SCB has many facets to consider, one of which is public preparedness and support for the bank. This was assessed in a social feasibility pilot study which is reported here. In addition to the findings of this social feasibility study, other important considerations for establishing a public human UCB SCB in SA include; (a) testing the samples for HIV and other infectious diseases (required for compliance with international regulatory standards); (b) flow cytometric analysis for enumeration of CD34+ UCB stem cells; (c) mapping of HLA genotypes/alleles; and (d) a study of the economic feasibility of this endeavour.The social feasibility study was conducted to gauge public preparedness and support for a public SCB through patient interviews and questionnaires. The process was dynamic due to its novel nature for interviewers and interviewees alike. Many obstacles were met and dealt with which lead to the compilation of results discussed here in the form of a pilot social feasibility study.In the South African context, we are faced with unique and rich challenges relating to cultural and religious differences that are further augmented by linguistic constraints, educational insufficiencies and logistical and administrative limitations. Complicating factors encountered during the informed consent process included cultural differences, religious practices, traditions and superstitions together with language constraints and an educational disparity.Despite many initial obstacles, preliminary results from the informed consent questionnaire were favourable with regard to the establishment of a public UCB SCB. These initial results prompted the revision of the questionnaire and interview process and the compilation of a more succinct and coherent definitive social feasibility study which will form a separate study and which we hope will ultimately assist in the decision of whether or not to establish a public UCB SCB in South Africa. Nevertheless, results from this pilot study appear to be favourable and highlight particular areas which could influence community support for a public SCB. Educating the general public with regard to the workings and benefits of public stem cell banking is the first step in determining the viability of such an undertaking-a unique and rich challenge in the South African context.

Smouldering Remediation (STAR) Technology: Field Pilot Tests and First Full Scale Application

NASA Astrophysics Data System (ADS)

Gerhard, J.; Kinsman, L.; Torero, J. L.

2015-12-01

STAR (Self-sustaining Treatment for Active Remediation) is an innovative remediation technology based on the principles of smoldering combustion where the contaminants are the fuel. The self-sustaining aspect means that a single, local ignition event can result in many days of contaminant destruction in situ. Presented research to date has focused on bench scale experiments, numerical modelling and process understanding. Presented here is the maturation of the in situ technology, including three field pilot tests and a full-scale implementation to treat coal tar-impacted soils. The first pilot determined a Radius of Influence (ROI) for a single ignition of approximately eight feet with an average propagation rate of the reaction of approximately one foot per day. TPH concentrations in soils were reduced from 10,000 milligrams per kilogram to a few hundred milligrams per kilogram. The second pilot was conducted in an area of significant void spaces created through the anthropogenic deposition of clay bricks and tiles. The void spaces led to pre-mature termination of the combustion reaction, limiting ROI and the effectiveness of the technology in this setting. The third case study involved the pilot testing, design, and full-scale implementation of STAR at a 37-acre former chemical manufacturing facility. Three phases of pilot testing were conducted within two hydrogeologic units at the site (i.e., surficial fill and deep alluvial sand units). Pilot testing within the fill demonstrated self-sustained coal tar destruction rates in excess of 800 kg/day supported through air injection at a single well. Deep sand unit testing (twenty-five feet below the water table) resulted in the treatment of a targeted six-foot layer of impacted fine sands to a radial distance of approximately twelve feet. These results (and additional parameters) were used to develop a full-scale STAR design consisting of approximately 1500 surficial fill ignition points and 500 deep sand ignition points and two treatment (air distribution and vapor collection / treatment) systems to remediate an approximately 14-acre footprint of contaminated soils within the project timelines (i.e., by mid-2016). Field activities began in 2014 and progress is currently on-schedule.

APOLLO-SOYUZ TEST PROJECT (ASTP) - CREWMEN - JSC

NASA Image and Video Library

1975-07-09

S75-28361 (9 July 1975) --- These ten American astronauts compose the U.S. prime crew, the backup crew and the crew support team for the joint U.S.-USSR Apollo-Soyuz Test Project docking mission in Earth orbit. They are, left to right, Robert L. Crippen, support team; Robert F. Overmyer, support team; Richard H. Truly, support team; Karol J. Bobko, support team; Donald K. Slayton, prime crew docking module pilot; Thomas P. Stafford, prime crew commander; Vance D. Brand, prime crew command module pilot; Jack R. Lousma, backup crew docking module pilot; Ronald E. Evans, backup crew command module pilot; and Alan L. Bean, backup crew commander. They are photographed by the Apollo Mission Simulator console in Building 5 at NASA's Johnson Space Center.

Effect of vertical active vibration isolation on tracking performance and on ride qualities

NASA Technical Reports Server (NTRS)

Dimasi, F. P.; Allen, R. E.; Calcaterra, P. C.

1972-01-01

An investigation to determine the effect on pilot performance and comfort of an active vibration isolation system for a commercial transport pilot seat is reported. The test setup consisted of: a hydraulic shaker which produced random vertical vibration inputs; the active vibration isolation system; the pilot seat; the pilot control wheel and column; the side-arm controller; and a two-axis compensatory tracking task. The effects of various degrees of pilot isolation on short-term (two-minute) tracking performance and comfort were determined.

A Piloted Simulation Investigating Handling Qualities and Performance Requirements of a Single-Pilot Helicopter in Air Combat Employing a Helmet-Driven Turreted Gun.

DTIC Science & Technology

1987-09-01

Jeffrey N. Williams September 1987 Thesis Advisor Donald M. Layton Approved for public release; distribution is unlimited. 7 14 44 r uaKjjW...I . - TBLE 9 PARTICIPATING EVALUATION PILOTS CW 2 John Burt, US. Army MAI Eric L Mitchell, U.S. Army ACM Instructor Pilot, Utah ANG Test Pilot...M. Layton , Code 67Ln I Department of Aeronautics Naval Postgraduate School Monterey, CA 93943 5. Dr. J. Victor Lebacqz 6 Chief, Flight Dynamics and

Effect of flame-tube head structure on combustion chamber performance

NASA Technical Reports Server (NTRS)

Gu, Minqqi

1986-01-01

The experimental combustion performance of a premixed, pilot-type flame tube with various head structures is discussed. The test study covers an extensive area: efficiency of the combustion chamber, quality of the outlet temperature field, limit of the fuel-lean blowout, ignition performance at ground starting, and carbon deposition. As a result of these tests, a nozzle was found which fits the premixed pilot flame tube well. The use of this nozzle optimized the performance of the combustion chamber. The tested models had premixed pilot chambers with two types of air-film-cooling structures, six types of venturi-tube structures, and secondary fuel nozzles with two small spray-cone angles.

USAF Test Pilot School. Flying Qualities Textbook, Volume 2, Part 1

DTIC Science & Technology

1986-04-01

Qualities Flight Testing, Performance and Flying Qaulities Branch, Flight Test Engneerd ision, 6510th Test Wing, Air Force Flight Mayst Ce1ter, Edwards...For these aircraft, the program manager may re*uire a mil spec written specifically for the aircraft and control system involwd. 5.20.2 _EL k,Tt...OR MANAGED IN CONTEXT OF MISSION, WITH AVAILABLE PILOT ATTENTION. S UNCONTROLLABLE CONTROL WILL BE LOST DURING SOME PORTION OF MISSION. ACCEPTABLE

Program Manager: Journal of the Defense Systems Management College. Volume 16, Number 3, May-June 1987

DTIC Science & Technology

1987-06-01

redress a growingstrategic imbalance and provide an en- test pilots conducted a rigorous flight test during capability to penetrate Soviet program...ment career path for rated officers vidual rotates through assignments in ( pilots and navigators) is different from engineering, test and evaluation...pain. Acquiring the B-1B, or any other weapon system for that matter, entails developing, testing ard producing new technology. In any high-tech en

Standardization and assessment of cell culture media quantities in roller poly ethylene terephthalate bottles employed in the industrial rabies viral vaccine production.

PubMed

Jagannathan, S; Chaansha, S; Rajesh, K; Santhiya, T; Charles, C; Venkataramana, K N

2009-09-15

Vero cells are utilized for production of rabies vaccine. This study deals with the optimize quantity media require for the rabies vaccine production in the smooth roller surface. The rabies virus (Pasteur vaccine strain) is infected to monolayer of the various experimented bottles. To analyze the optimal quantity of media for the production of rabies viral harvest during the process of Vero cell derived rabies vaccine. The trials are started from 200 to 400 mL (PTARV-1, PTARV-2, PTARV-3, PTARV-4 and PTARV-5). The samples are taken in an appropriate time intervals for analysis of In Process Quality Control (IPQC) tests. The collected viral harvests are further processed to rabies vaccine in a pilot level and in addition to scale up an industrial level. Based on the evaluation the PTARV-2 (250 mL) show highly encouraging results for the Vero cell derived rabies vaccine production.

An In vivo Model for Short-Term Evaluation of the Implantation Effects of Biomolecules or Stem Cells in the Dental Pulp

PubMed Central

Lacerda-Pinheiro, Sally; Marchadier, Arnaud; Donãs, Patricio; Septier, Dominique; Benhamou, Laurent; Kellermann, Odile; Goldberg, Michel; Poliard, Anne

2008-01-01

The continuously growing rodent incisor is a widely used model to investigate odontogenesis and mineralized tissue formation. This study focused on evaluating the mouse mandibular incisor as an experimental biological tool for analyzing in vivo the capacity of odontoblast-like progenitors or bioactive molecules to contribute to reparative dentinogenesis. We describe here a surgical procedure allowing direct access to the forming part of the incisor dental pulp Amelogenin peptide A+4 adsorbed on agarose beads, or dental pulp progenitor cells were implanted in the pulp following this procedure. After 10 days A+4 induced the formation of an osteodentin occluding almost the totality of the pulp compartment. Implantation of progenitor cells leads to formation of islets of osteodentin-like structures located centrally in the pulp. These pilot studies validate the incisor as an experimental model to test the capacity of progenitor cells or bioactive molecules to induce the formation of reparative dentin. PMID:19088885

STS-44 Pilot Henricks uses Visual Function Tester (VFT) on OV-104's middeck

NASA Image and Video Library

1991-12-01

STS044-14-013 (24 Nov-1 Dec 1991) --- Terence T. (Tom) Henricks, STS-44 pilot, tests his visual acuity with the Visual Function Test (VFT) apparatus. This photograph was among the first released by NASA following the eight day mission, dedicated to the Department of Defense.

The Right Administrative Stuff

ERIC Educational Resources Information Center

Dustin, Dan; McDonald, Cary; Harper, Jack; Lamke, Gene; Murphy, James

2014-01-01

This article is intended to provoke thought and discussion about what it takes to be a department chair and what it feels like to be a department chair. To accomplish our purpose, we draw an analogy between test pilots and department chairs based on Tom Wolfe's "The Right Stuff" (1979). We reason that test pilots and department…

Measuring Literary Reading Motivation: Questionnaires Design and Pilot Testing

ERIC Educational Resources Information Center

Chrysos, Michail

2017-01-01

This study aims to present the design and pilot testing procedures of the two specific self-report questionnaires were used to measure the two key aspects of reading motivation, self-efficacy and intrinsic motivation in the field of literary (narrative) reading, and the partial factors that jointly shape them. These instruments were outlined in…

REVIEW OF BENCH-, PILOT-, AND FULL-SCALE ORIMULSION (R) COMBUSTION TESTS

EPA Science Inventory

The paper gives results of a review of bench-, pilot-, and full-scale Orimulsion combustion tests. A fossil fuel marketed by its producer, Petroleos de Venezuela, S.A. (PdVSA), since the late 1980s as an alternative to coal and heavy fuel oil, Orimulsion is a bitumen-in-water em...

Gemini-Titan (GT)-9 Test - Training - KSC

NASA Image and Video Library

1966-06-10

S66-33406 (10 May 1966) --- Astronaut Thomas P. Stafford (on left), command pilot, and Eugene A. Cernan, pilot, in Gemini-9 spacecraft in the white room at Pad 19 during a Gemini-9/Agena simultaneous launch demonstration. This test is a coordinated dountdown of the Atlas-Agena and the Gemini-Titan vehicles. Photo credit: NASA

Guidelines on Pilot and Field Testing of Curriculum Products.

ERIC Educational Resources Information Center

Contract Research Corp., Belmont, MA.

This booklet is intended to aid curriculum developers in designing and conducting pilot or field tests that yield useful information and sound evidence about the effectiveness of new curricula. Although it was prepared specifically for use by projects funded by the Curriculum Development Branch of the federal Bureau of Occupational and Adult…

Electronic Thesis Initiative: Pilot Project of McGill University, Montreal

ERIC Educational Resources Information Center

Park, Eun G.; Zou, Qing; McKnight, David

2007-01-01

Purpose: To set up a protocol for electronic thesis and dissertation (ETD) submission for the electronic thesis initiative pilot project at McGill University in Montreal, Canada. Design/methodology/approach: An electronic thesis and dissertation submission protocol was implemented and tested. To test authoring tools, we had 50 students submit…

PILOT-SCALE PARAMETRIC TESTING OF SPRAY DRYER SO2 SCRUBBER FOR LOW-TO-MODERATE SULFUR COAL UTILITY APPLICATIONS

EPA Science Inventory

The report gives results of a comprehensive, pilot, dry, SO2 scrubbing test program to determine the effects of process variables on SO2 removal. In the spray dryer, stoichiometric ratio, flue gas temperature approach to adiabatic saturation, and temperature drop across the spray...

Measuring the Immeasurable: A Pilot Study of Museum Effectiveness.

ERIC Educational Resources Information Center

Borun, Minda

The report describes a one-year pilot study of museum effectiveness conducted at the Franklin Institute Science Museum and Planetarium in Philadelphia. The study was intended to develop models for testing visitor response, provide useable information to museum staff, and test the feasibility of a large-scale investigation of science museums.…

Solar photocatalytic degradation of some hazardous water-soluble pesticides at pilot-plant scale.

PubMed

Oller, I; Gernjak, W; Maldonado, M I; Pérez-Estrada, L A; Sánchez-Pérez, J A; Malato, S

2006-12-01

The technical feasibility and performance of photocatalytic degradation of six water-soluble pesticides (cymoxanil, methomyl, oxamyl, dimethoate, pyrimethanil and telone) have been studied at pilot-plant scale in two well-defined systems which are of special interest because natural solar UV light can be used: heterogeneous photocatalysis with titanium dioxide and homogeneous photocatalysis by photo-Fenton. TiO(2) photocatalysis tests were performed in a 35L solar pilot plant with three Compound Parabolic Collectors (CPCs) under natural illumination and a 75L solar pilot plant with four CPC units was used for homogeneous photocatalysis tests. The initial pesticide concentration studied was 50 mg L(-1) and the catalyst concentrations employed were 200 mg L(-1) of TiO(2) and 20 mg L(-1) of iron. Both toxicity (Vibrio fischeri, Biofix) and biodegradability (Zahn-Wellens test) of the initial pesticide solutions were also measured. Total disappearance of the parent compounds and nearly complete mineralization were attained with all pesticides tested. Treatment time, hydrogen peroxide consumption and release of heteroatoms are discussed.

T Cells

MedlinePlus

... cells — have proven successful in treating animals with experimental allergic encephalomyelitis (EAE), an animal model of MS. Pilot clinical trials are in progress. Future experimental therapies may involve antibodies directed against the cytokines ...

The development of a science process assessment for fourth-grade students

NASA Astrophysics Data System (ADS)

Smith, Kathleen A.; Welliver, Paul W.

In this study, a multiple-choice test entitled the Science Process Assessment was developed to measure the science process skills of students in grade four. Based on the Recommended Science Competency Continuum for Grades K to 6 for Pennsylvania Schools, this instrument measured the skills of (1) observing, (2) classifying, (3) inferring, (4) predicting, (5) measuring, (6) communicating, (7) using space/time relations, (8) defining operationally, (9) formulating hypotheses, (10) experimenting, (11) recognizing variables, (12) interpreting data, and (13) formulating models. To prepare the instrument, classroom teachers and science educators were invited to participate in two science education workshops designed to develop an item bank of test questions applicable to measuring process skill learning. Participants formed writing teams and generated 65 test items representing the 13 process skills. After a comprehensive group critique of each item, 61 items were identified for inclusion into the Science Process Assessment item bank. To establish content validity, the item bank was submitted to a select panel of science educators for the purpose of judging item acceptability. This analysis yielded 55 acceptable test items and produced the Science Process Assessment, Pilot 1. Pilot 1 was administered to 184 fourth-grade students. Students were given a copy of the test booklet; teachers read each test aloud to the students. Upon completion of this first administration, data from the item analysis yielded a reliability coefficient of 0.73. Subsequently, 40 test items were identified for the Science Process Assessment, Pilot 2. Using the test-retest method, the Science Process Assessment, Pilot 2 (Test 1 and Test 2) was administered to 113 fourth-grade students. Reliability coefficients of 0.80 and 0.82, respectively, were ascertained. The correlation between Test 1 and Test 2 was 0.77. The results of this study indicate that (1) the Science Process Assessment, Pilot 2, is a valid and reliable instrument applicable to measuring the science process skills of students in grade four, (2) using educational workshops as a means of developing item banks of test questions is viable and productive in the test development process, and (3) involving classroom teachers and science educators in the test development process is educationally efficient and effective.

SELECTIVE DISSEMINATION OF INFORMATION (SDI). VOLUME I, PILOT TEST AT U.S. ARMY NATICK LABORATORIES. FINAL REPORT. ARMY TECHNICAL LIBRARY IMPROVEMENT STUDIES (ATLIS), REPORT NO. 15.

ERIC Educational Resources Information Center

BIVONA, WILLIAM A.

THIS VOLUME PRESENTS THE RESULTS OF A NINE-MONTH TEST OF A PROTOTYPE SELECTIVE DISSEMINATION OF INFORMATION (SDI) SYSTEM DEVELOPED FOR THE ARMY TECHNICAL LIBRARIES. DURING THE PILOT TEST ONE THOUSAND DOCUMENTS WERE CATALOGED, INDEXED, AND DISSEMINATED TO TWENTY-FIVE SCIENTIFIC AND TECHNICAL PERSONNEL. MATCHING OF THE INTEREST PROFILES OF THESE…

Pilot-in-the-Loop CFD Method Development

DTIC Science & Technology

2017-04-20

the methods on the NAVAIR Manned Flight Simulator. Activities this period During this report period, we implemented the CRAFT CFD code on the...Penn State VLRCROE Flight simulator and performed the first Pilot-in-the-Loop PILCFD tests at Penn State using the COCOA5 clusters. The initial tests...integration of the flight simulator and Penn State computing infrastructure. Initial tests showed slower performance than real-time (3x slower than real

Step 1: Human System Integration Simulation and Flight Test Progress Report

NASA Technical Reports Server (NTRS)

2005-01-01

The Access 5 Human Systems Integration Work Package produced simulation and flight demonstration planning products for use throughout the program. These included: Test Objectives for Command, Control, Communications; Pilot Questionnaire for Command, Control, Communications; Air Traffic Controller Questionnaire for Command, Control, Communications; Test Objectives for Collision Avoidance; Pilot Questionnaire for Collision Avoidance; Plans for Unmanned Aircraft Systems Control Station Simulations Flight Requirements for the Airspace Operations Demonstration

The Development, Test, and Evaluation of Three Pilot Performance Reference Scales.

ERIC Educational Resources Information Center

Horner, Walter R.; And Others

A set of pilot performance reference scales was developed based upon airborne Audio-Video Recording (AVR) of student performance in T-37 undergraduate Pilot Training. After selection of the training maneuvers to be studied, video tape recordings of the maneuvers were selected from video tape recordings already available from a previous research…

ON-SITE ENGINEERING REPORT OF THE SLURRY-PHASE BIOLOGICAL REACTOR FOR PILOT-SCALE TESTING ON CONTAMINATED SOIL

EPA Science Inventory

The performance of pilot-scale bioslurry treatment on creosote-contaminated soil was evaluated. Five reactors containing 66 L of slurry (30% soil by weight), were operated in parallel. The soil was a sandy soil with minor gravel content. The pilot-scale phase utilized an inoculum...

The use of vestibular tests in civil aviation medical examinations : survey of practices and proposals by aviation medical examiners.

DOT National Transportation Integrated Search

1975-01-01

The medical records of airmen involved in midair collisions from 1970 through 1973 were reviewed and compared with two other groups of pilots: (1) pilots involved in other types of accidents and (2) pilots without any accident records. There is nothi...

Could situational judgement tests be used for selection into dental foundation training?

PubMed

Patterson, F; Ashworth, V; Mehra, S; Falcon, H

2012-07-13

To pilot and evaluate a machine-markable situational judgement test (SJT) designed to select candidates into UK dental foundation training. Single centre pilot study. UK postgraduate deanery in 2010. Seventy-four candidates attending interview for dental foundation training in Oxford and Wessex Deaneries volunteered to complete the situational judgement test. The situational judgement test was developed to assess relevant professional attributes for dentistry (for example, empathy and integrity) in a machine-markable format. Test content was developed by subject matter experts working with experienced psychometricians. Evaluation of psychometric properties of the pilot situational judgement test (for example, reliability, validity and fairness). Scores in the dental foundation training selection process (short-listing and interviews) were used to examine criterion-related validity. Candidates completed an evaluation questionnaire to examine candidate reactions and face validity of the new test. Forty-six candidates were female and 28 male; mean age was 23.5-years-old (range 22-32). Situational judgement test scores were normally distributed and the test showed good internal reliability when corrected for test length (α = 0.74). Situational judgement test scores positively correlated with the management, leadership and professionalism interview (N = 50; r = 0.43, p <0.01) but not with the clinical skills interview, providing initial evidence of criterion-related validity as the situational judgement test is designed to test non-cognitive professional attributes beyond clinical knowledge. Most candidates perceived the situational judgement test as relevant to dentistry, appropriate for their training level, and fair. This initial pilot study suggests that a situational judgement test is an appropriate and innovative method to measure professional attributes (eg empathy and integrity) for selection into foundation training. Further research will explore the long-term predictive validity of the situational judgement test once candidates have entered training.

Pilot Joseph Algranti entering a McDonnell F2H-2B Banshee

NASA Image and Video Library

1958-02-21

Pilot Joe Algranti climbs into the cockpit of a McDonnell F2H-2B Banshee on the tarmac at the National Advisory Committee for Aeronautics (NACA) Lewis Flight Propulsion Laboratory. Nine months later the laboratory became part of the new National Aeronautics and Space Administration, and the NACA logo was permanently removed from the hangar. Algranti served as a Navy fighter pilot from 1946 to 1947 and earned a Physics degree from the University of North Carolina. He joined the NACA Lewis staff in 1951 witnessed the technological transformation from high speed flight to space. At Lewis Algranti piloted icing research flights, operated the liquid-hydrogen pump system for Project Bee, and served as the primary test subject for the Multi-Axis Space Test Inertia Facility (MASTIF). The MASTIF was a device used to train the Mercury astronauts how to control a spinning capsule. In 1960, Algranti and fellow Lewis pilots Warren North and Harold Ream transferred to NASA’s Space Task Group at Langley to actively participate in the space program. Two years later, Algranti became the Chief of Aircraft Operations and Chief Test Pilot at NASA’s new Manned Space Center in Houston. Algranti earned notoriety in 1968 when he test flew the first Lunar Landing Training Vehicle. He operated the vehicle four minutes before being forced to eject moments before it impacted the ground. Algranti also flew the NASA’s modified Boeing 747 Shuttle Carrier Aircraft, the Super Guppy, and the KC-135 "Vomit Comet" training aircraft. He retired in 1992 with over 40 years of NASA service.

Development and Feasibility of a Structured Goals of Care Communication Guide.

PubMed

Bekelman, David B; Johnson-Koenke, Rachel; Ahluwalia, Sangeeta C; Walling, Anne M; Peterson, Jamie; Sudore, Rebecca L

2017-09-01

Discussing goals of care and advance care planning is beneficial, yet how to best integrate goals of care communication into clinical care remains unclear. To develop and determine the feasibility of a structured goals of care communication guide for nurses and social workers. Developmental study with providers in an academic and Veterans Affairs (VA) health system (n = 42) and subsequent pilot testing with patients with chronic obstructive pulmonary disease or heart failure (n = 15) and informal caregivers (n = 4) in a VA health system. During pilot testing, the communication guide was administered, followed by semistructured, open-ended questions about the content and process of communication. Changes to the guide were made iteratively, and subsequent piloting occurred until no additional changes emerged. Provider and patient feedback to the communication guide. Iterative input resulted in the goals of care communication guide. The guide included questions to elicit patient understanding of and attitudes toward the future of illness, clarify values and goals, identify end-of-life preferences, and agree on a follow-up plan. Revisions to guide content and phrasing continued during development and pilot testing. In pilot testing, patients validated the importance of the topic; none said the goals of care discussion should not be conducted. Patients and informal caregivers liked the final guide length (∼30 minutes), felt it flowed well, and was clear. In this developmental and pilot study, a structured goals of care communication guide was iteratively designed, implemented by nurses and social workers, and was feasible based on administration time and acceptability by patients and providers.

The effect of aircraft control forces on pilot performance during instrument landings in a flight simulator.

PubMed

Hewson, D J; McNair, P J; Marshall, R N

2001-07-01

Pilots may have difficulty controlling aircraft at both high and low force levels due to larger variability in force production at these force levels. The aim of this study was to measure the force variability and landing performance of pilots during an instrument landing in a flight simulator. There were 12 pilots who were tested while performing 5 instrument landings in a flight simulator, each of which required different control force inputs. Pilots can produce the least force when pushing the control column to the right, therefore the force levels for the landings were set relative to each pilot's maximum aileron-right force. The force levels for the landings were 90%, 60%, and 30% of maximal aileron-right force, normal force, and 25% of normal force. Variables recorded included electromyographic activity (EMG), aircraft control forces, aircraft attitude, perceived exertion and deviation from glide slope and heading. Multivariate analysis of variance was used to test for differences between landings. Pilots were least accurate in landing performance during the landing at 90% of maximal force (p < 0.05). There was also a trend toward decreased landing performance during the landing at 25% of normal force. Pilots were more variable in force production during the landings at 60% and 90% of maximal force (p < 0.05). Pilots are less accurate at performing instrument landings when control forces are high due to the increased variability of force production. The increase in variability at high force levels is most likely associated with motor unit recruitment, rather than rate coding. Aircraft designers need to consider the reduction in pilot performance at high force levels, as well as pilot strength limits when specifying new standards.

Introduction of Syphilis Point-of-Care Tests, from Pilot Study to National Programme Implementation in Zambia: A Qualitative Study of Healthcare Workers' Perspectives on Testing, Training and Quality Assurance.

PubMed

Ansbro, Éimhín M; Gill, Michelle M; Reynolds, Joanna; Shelley, Katharine D; Strasser, Susan; Sripipatana, Tabitha; Tshaka Ncube, Alexander; Tembo Mumba, Grace; Terris-Prestholt, Fern; Peeling, Rosanna W; Mabey, David

2015-01-01

Syphilis affects 1.4 million pregnant women globally each year. Maternal syphilis causes congenital syphilis in over half of affected pregnancies, leading to early foetal loss, pregnancy complications, stillbirth and neonatal death. Syphilis is under-diagnosed in pregnant women. Point-of-care rapid syphilis tests (RST) allow for same-day treatment and address logistical barriers to testing encountered with standard Rapid Plasma Reagin testing. Recent literature emphasises successful introduction of new health technologies requires healthcare worker (HCW) acceptance, effective training, quality monitoring and robust health systems. Following a successful pilot, the Zambian Ministry of Health (MoH) adopted RST into policy, integrating them into prevention of mother-to-child transmission of HIV clinics in four underserved Zambian districts. We compare HCW experiences, including challenges encountered in scaling up from a highly supported NGO-led pilot to a large-scale MoH-led national programme. Questionnaires were administered through structured interviews of 16 HCWs in two pilot districts and 24 HCWs in two different rollout districts. Supplementary data were gathered via stakeholder interviews, clinic registers and supervisory visits. Using a conceptual framework adapted from health technology literature, we explored RST acceptance and usability. Quantitative data were analysed using descriptive statistics. Key themes in qualitative data were explored using template analysis. Overall, HCWs accepted RST as learnable, suitable, effective tools to improve antenatal services, which were usable in diverse clinical settings. Changes in training, supervision and quality monitoring models between pilot and rollout may have influenced rollout HCW acceptance and compromised testing quality. While quality monitoring was integrated into national policy and training, implementation was limited during rollout despite financial support and mentorship. We illustrate that new health technology pilot research can rapidly translate into policy change and scale-up. However, training, supervision and quality assurance models should be reviewed and strengthened as rollout of the Zambian RST programme continues.

Introduction of Syphilis Point-of-Care Tests, from Pilot Study to National Programme Implementation in Zambia: A Qualitative Study of Healthcare Workers’ Perspectives on Testing, Training and Quality Assurance

PubMed Central

Ansbro, Éimhín M.; Gill, Michelle M.; Reynolds, Joanna; Shelley, Katharine D.; Strasser, Susan; Sripipatana, Tabitha; Ncube, Alexander Tshaka; Tembo Mumba, Grace; Terris-Prestholt, Fern; Peeling, Rosanna W.; Mabey, David

2015-01-01

Syphilis affects 1.4 million pregnant women globally each year. Maternal syphilis causes congenital syphilis in over half of affected pregnancies, leading to early foetal loss, pregnancy complications, stillbirth and neonatal death. Syphilis is under-diagnosed in pregnant women. Point-of-care rapid syphilis tests (RST) allow for same-day treatment and address logistical barriers to testing encountered with standard Rapid Plasma Reagin testing. Recent literature emphasises successful introduction of new health technologies requires healthcare worker (HCW) acceptance, effective training, quality monitoring and robust health systems. Following a successful pilot, the Zambian Ministry of Health (MoH) adopted RST into policy, integrating them into prevention of mother-to-child transmission of HIV clinics in four underserved Zambian districts. We compare HCW experiences, including challenges encountered in scaling up from a highly supported NGO-led pilot to a large-scale MoH-led national programme. Questionnaires were administered through structured interviews of 16 HCWs in two pilot districts and 24 HCWs in two different rollout districts. Supplementary data were gathered via stakeholder interviews, clinic registers and supervisory visits. Using a conceptual framework adapted from health technology literature, we explored RST acceptance and usability. Quantitative data were analysed using descriptive statistics. Key themes in qualitative data were explored using template analysis. Overall, HCWs accepted RST as learnable, suitable, effective tools to improve antenatal services, which were usable in diverse clinical settings. Changes in training, supervision and quality monitoring models between pilot and rollout may have influenced rollout HCW acceptance and compromised testing quality. While quality monitoring was integrated into national policy and training, implementation was limited during rollout despite financial support and mentorship. We illustrate that new health technology pilot research can rapidly translate into policy change and scale-up. However, training, supervision and quality assurance models should be reviewed and strengthened as rollout of the Zambian RST programme continues. PMID:26030741

FBIS report. Science and technology: Japan, December 10, 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-12-10

Contents (partial): Japan: Fabrication of Diamond Single Crystal Thin Film by Ion Beam Deposition; Japan: Hitachi Metal Develops New Semi Solid Metal Processing Technology; Japan: NTT Develops Fuel Cell System That Uses Both City Gas, LPG; Japan: Daihatsu Motor Completes Prototype EV; Japan: NIRIM Announces Success With Synthetic Bone Development; Japan: Sandoz Pharmaceuticals Plans Clinical Trials of Gene Therapy to Cerebral Tumor in Japan; Japan: MITI To Provide Aid for Residential Solar Power Generation Systems; Japan: MELCO To Provide Satellite Solar Cell Panel for SSL, USA; Japan: Japan Atomic Energy Research Institute Leads Nuclear Research; Japan: Kobe Steel`s Superconducting Magnetmore » Ready to Go Fast; Japan: MPT To Begin Validation Test for Electric Money Implementation; and Japan: Defense Agency to Send ASDF`s Pilots to Russia for Training.« less

M2-F3 with test pilot John A. Manke

NASA Image and Video Library

1972-12-20

NASA research pilot John A. Manke is seen here in front of the M2-F3 Lifting Body. Manke was hired by NASA on May 25, 1962, as a flight research engineer. He was later assigned to the pilot's office and flew various support aircraft including the F-104, F5D, F-111 and C-47. After leaving the Marine Corps in 1960, Manke worked for Honeywell Corporation as a test engineer for two years before coming to NASA. He was project pilot on the X-24B and also flew the HL-10, M2-F3, and X-24A lifting bodies. John made the first supersonic flight of a lifting body and the first landing of a lifting body on a hard surface runway. Manke served as Director of the Flight Operations and Support Directorate at the Dryden Flight Research Center prior to its integration with Ames Research Center in October 1981. After this date John was named to head the joint Ames-Dryden Directorate of Flight Operations. He also served as site manager of the NASA Ames-Dryden Flight Research Facility. John is a member of the Society of Experimental Test Pilots. He retired on April 27, 1984.

Advanced Transport Delay Compensation Algorithms: Results of Delay Measurement and Piloted Performance Tests

NASA Technical Reports Server (NTRS)

Guo, Liwen; Cardullo, Frank M.; Kelly, Lon C.

2007-01-01

This report summarizes the results of delay measurement and piloted performance tests that were conducted to assess the effectiveness of the adaptive compensator and the state space compensator for alleviating the phase distortion of transport delay in the visual system in the VMS at the NASA Langley Research Center. Piloted simulation tests were conducted to assess the effectiveness of two novel compensators in comparison to the McFarland predictor and the baseline system with no compensation. Thirteen pilots with heterogeneous flight experience executed straight-in and offset approaches, at various delay configurations, on a flight simulator where different predictors were applied to compensate for transport delay. The glideslope and touchdown errors, power spectral density of the pilot control inputs, NASA Task Load Index, and Cooper-Harper rating of the handling qualities were employed for the analyses. The overall analyses show that the adaptive predictor results in slightly poorer compensation for short added delay (up to 48 ms) and better compensation for long added delay (up to 192 ms) than the McFarland compensator. The analyses also show that the state space predictor is fairly superior for short delay and significantly superior for long delay than the McFarland compensator.

Pilot plant test of the advanced flash stripper for CO2 capture.

PubMed

Lin, Yu-Jeng; Chen, Eric; Rochelle, Gary T

2016-10-20

Alternative stripping processes have been proposed to reduce energy use for CO 2 capture, but only a few have been applied to pilot-scale experiments. This paper presents the first pilot plant test results of one of the most promising stripper configurations, the advanced flash stripper with cold and warm rich solvent bypass. The campaign using aqueous piperazine was carried out at UT Austin in 2015. The advanced flash stripper improves the heat duty by over 25% compared to previous campaigns using the two-stage flash, achieving 2.1 GJ per tonne CO 2 of heat duty and 32 kJ mol -1 CO 2 of total equivalent work. The bypass control strategy proposed minimized the heat duty. The test successfully demonstrated the remarkable energy performance and the operability of this advanced system. An Aspen Plus® model was validated using the pilot plant data and used to explore optimum operating and design conditions. The irreversibility analysis showed that the pilot plant performance has attained 50% thermodynamic efficiency and further energy improvement should focus on the absorber and the cross exchanger by increasing absorption rate and solvent capacity.

UTM Technical Capabilities Level 2 (TLC2) Test at Reno-Stead Airport.

NASA Image and Video Library

2016-10-06

Test of Unmanned Aircraft Systems Traffic Management (UTM) technical capability Level 2 (TCL2) at Reno-Stead Airport, Nevada. During the test, five drones simultaneously crossed paths, separated by altitude. Two drones flew beyond visual line-of-sight and three flew within line-of-sight of their operators. Precision Hawk pilot launches UAS Lancaster Mark 3, one of 11 vehicles in the UTM TCL2 demonstration that will fly beyond line of sight of the pilot in command in Nevada test.

Development of a pilot-scale kinetic extruder feeder system and test program. Phase II. Verification testing. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1984-01-12

This report describes the work done under Phase II, the verification testing of the Kinetic Extruder. The main objective of the test program was to determine failure modes and wear rates. Only minor auxiliary equipment malfunctions were encountered. Wear rates indicate useful life expectancy of from 1 to 5 years for wear-exposed components. Recommendations are made for adapting the equipment for pilot plant and commercial applications. 3 references, 20 figures, 12 tables.

CONSTRUCTION PROGRESS PHOTO OF HOT PILOT PLANT (CPP640) LOOKING NORTHWEST, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

CONSTRUCTION PROGRESS PHOTO OF HOT PILOT PLANT (CPP-640) LOOKING NORTHWEST, SHOWING FORMING FOR NORTH WALLS OF CELLS 1, 4 AND 5; CONSTRUCTION 21 PERCENT COMPLETE. INL PHOTO NUMBER NRTS-60-1874. Holmes, Photographer, 4/21/1960 - Idaho National Engineering Laboratory, Idaho Chemical Processing Plant, Fuel Reprocessing Complex, Scoville, Butte County, ID

Scaling Down to Scale Up: A Health Economic Analysis of Integrating Point-of-Care Syphilis Testing into Antenatal Care in Zambia during Pilot and National Rollout Implementation

PubMed Central

Ncube, Alexander Tshaka; Sweeney, Sedona; Fleischer, Colette; Mumba, Grace Tembo; Gill, Michelle M.; Strasser, Susan; Peeling, Rosanna W.; Terris-Prestholt, Fern

2015-01-01

Maternal syphilis results in an estimated 500,000 stillbirths and neonatal deaths annually in Sub-Saharan Africa. Despite the existence of national guidelines for antenatal syphilis screening, syphilis testing is often limited by inadequate laboratory and staff services. Recent availability of inexpensive rapid point-of-care syphilis tests (RST) can improve access to antenatal syphilis screening. A 2010 pilot in Zambia explored the feasibility of integrating RST within prevention of mother-to-child-transmission of HIV services. Following successful demonstration, the Zambian Ministry of Health adopted RSTs into national policy in 2011. Cost data from the pilot and 2012 preliminary national rollout were extracted from project records, antenatal registers, clinic staff interviews, and facility observations, with the aim of assessing the cost and quality implications of scaling up a successful pilot into a national rollout. Start-up, capital, and recurrent cost inputs were collected, including costs of extensive supervision and quality monitoring during the pilot. Costs were analysed from a provider’s perspective, incremental to existing antenatal services. Total and unit costs were calculated and a multivariate sensitivity analysis was performed. Our accompanying qualitative study by Ansbro et al. (2015) elucidated quality assurance and supervisory system challenges experienced during rollout, which helped explain key cost drivers. The average unit cost per woman screened during rollout ($11.16) was more than triple the pilot unit cost ($3.19). While quality assurance costs were much lower during rollout, the increased unit costs can be attributed to several factors, including higher RST prices and lower RST coverage during rollout, which reduced economies of scale. Pilot and rollout cost drivers differed due to implementation decisions related to training, supervision, and quality assurance. This study explored the cost of integrating RST into antenatal care in pilot and national rollout settings, and highlighted important differences in costs that may be observed when moving from pilot to scale-up. PMID:25970443

Scaling Down to Scale Up: A Health Economic Analysis of Integrating Point-of-Care Syphilis Testing into Antenatal Care in Zambia during Pilot and National Rollout Implementation.

PubMed

Shelley, Katharine D; Ansbro, Éimhín M; Ncube, Alexander Tshaka; Sweeney, Sedona; Fleischer, Colette; Tembo Mumba, Grace; Gill, Michelle M; Strasser, Susan; Peeling, Rosanna W; Terris-Prestholt, Fern

2015-01-01

Maternal syphilis results in an estimated 500,000 stillbirths and neonatal deaths annually in Sub-Saharan Africa. Despite the existence of national guidelines for antenatal syphilis screening, syphilis testing is often limited by inadequate laboratory and staff services. Recent availability of inexpensive rapid point-of-care syphilis tests (RST) can improve access to antenatal syphilis screening. A 2010 pilot in Zambia explored the feasibility of integrating RST within prevention of mother-to-child-transmission of HIV services. Following successful demonstration, the Zambian Ministry of Health adopted RSTs into national policy in 2011. Cost data from the pilot and 2012 preliminary national rollout were extracted from project records, antenatal registers, clinic staff interviews, and facility observations, with the aim of assessing the cost and quality implications of scaling up a successful pilot into a national rollout. Start-up, capital, and recurrent cost inputs were collected, including costs of extensive supervision and quality monitoring during the pilot. Costs were analysed from a provider's perspective, incremental to existing antenatal services. Total and unit costs were calculated and a multivariate sensitivity analysis was performed. Our accompanying qualitative study by Ansbro et al. (2015) elucidated quality assurance and supervisory system challenges experienced during rollout, which helped explain key cost drivers. The average unit cost per woman screened during rollout ($11.16) was more than triple the pilot unit cost ($3.19). While quality assurance costs were much lower during rollout, the increased unit costs can be attributed to several factors, including higher RST prices and lower RST coverage during rollout, which reduced economies of scale. Pilot and rollout cost drivers differed due to implementation decisions related to training, supervision, and quality assurance. This study explored the cost of integrating RST into antenatal care in pilot and national rollout settings, and highlighted important differences in costs that may be observed when moving from pilot to scale-up.

Test pilots 1952 - Walker, Butchart, and Jones

NASA Technical Reports Server (NTRS)

1952-01-01

This photo shows test pilots, (Left-Right) Joseph A. Walker, Stanley P. Butchart and Walter P. Jones, standing in front of the Douglas D-558-II Skystreak, in 1952. These three test pilots at the National Advisory Committee for Aeronautics' High-Speed Flight Research Station probably were discussing their flights in the aircraft. Joe flew research flights on the D-558-I #3 (14 flights, first on June 29, 1951) investigating buffeting, tail loads, and longitudinal stability. He flew the D-558-II #2 (3 flights, first on April 29, 1955) and recorded data on lateral stability and control. He also made pilot check-out flights in the D-558-II #3 (2 flights, first on May 7, 1954). For fifteen years Walker served as a pilot at the Edwards flight research facility (today known as the National Aeronautics and Space Administration's Dryden Flight Research Center) on research flights as well as chase missions for other pilots on NASA and Air Force research programs. On June 8, 1966, he was flying chase in NASA's F-104N for the Air Force's experimental bomber, North American XB-70A, when he was fatally injured in a mid-air collision between the planes. Stan flew the D-558-I #3 (12 flights, first on October 19, 1951) to determine the dynamic longitudinal stability characteristics and investigations of the lateral stability and control. He made one flight in the D-558-II #3 on June 26, 1953, as a pilot check-out flight. Butchart retired from the NASA Dryden Flight Research Center at Edwards, California, on February 27, 1976, after a 25-year career in research aviation. Stan served as a research pilot, chief pilot, and director of flight operations. Walter P. Jones was a research pilot for NACA from the fall of 1950 to July 1952. He had been in the U.S. Air Force as a pilot before joining the Station. Jones flew the D-558-I #3 (5 flights, first on February 13, 1951) to study buffeting, tail loads and longitudinal stability. Jones made research flights on the D-558-II #3 ( 7 flights, first on July 20, 1951). These flights investigated pitch-up and evaluated outboard wing fences. Walt also made research flights in the Northrop X-4 (14 flights, first on March 26, 1952) and the Bell X-5 (8 flights, first on June 20, 1952). In July 1952, Walt left NACA's High-Speed Flight Research Station to join Northrop Corporation as a pilot. Returning from a test mission in a Northrop YF-89D Scorpion he was fatally injured on October 20, 1953, near Edwards Air Force Base.

Unmanned Aircraft Systems (UAS) Integration in the National Airspace System (NAS) Project: Terminal Operations HITL 1: Primary Results

NASA Technical Reports Server (NTRS)

Rorie, Conrad; Fern, Lisa; Monk, Kevin; Roberts, Zach; Brandt, Summer

2017-01-01

This presentation covers the primary results of the Unmanned Aircraft Systems (UAS) Integration in the National Airspace System (NAS) Project Terminal Operations Foundational Human-in-the-Loop (HITL) simulation. The study tasked 16 pilots (half with manned piloting experience, and the other half with unmanned piloting experience) with maintaining "well clear" from other traffic while performing three different types of approaches into the Santa Rosa airport. A detect and avoid (DAA) system was provided to pilots to assist their ability to manage separation. The DAA system used in this test conformed to the criteria defined by RTCA Special Committee 228 (SC-228) in their Phase 1 Minimum Operational Performance Standards (MOPS) for UAS intending to operate in the NAS. The Phase 1 system was not designed to account for terminal operations, focusing instead on en route operations. To account for this, three different alerting and guidance configurations were presently tested in order to determine their effect on pilots operating the system in the terminal area. Results indicated that pilots with the alerting and guidance condition that provided the least amount of assistance (fewer alert levels and guidance types) experienced slightly increased pilot response times and rates of losses of separation. Additional data is presented on the effects of approach type and descriptive data on pilot maneuver preferences and ATC interoperability.

F-8 SCW on ramp with test pilot Tom McMurtry

NASA Image and Video Library

1972-12-20

A Vought F-8A Crusader was selected by NASA as the testbed aircraft (designated TF-8A) to install an experimental Supercritical Wing (SCW) in place of the conventional wing. The unique design of the Supercritical Wing reduces the effect of shock waves on the upper surface near Mach 1, which in turn reduces drag. In this photograph the TF-8A Crusader with Supercritical Wing is shown on the ramp with project pilot Tom McMurtry standing beside it. McMurtry received NASA's Exceptional Service Medal for his work on the F-8 SCW aircraft. He also flew the AD-1, F-15 Digital Electronic Engine Control, the KC-130 winglets, the F-8 Digital Fly-By-Wire and other flight research aircraft including the remotely piloted 720 Controlled Impact Demonstration and sub-scale F-15 research projects. In addition, McMurtry was the 747 co-pilot for the Shuttle Approach and Landing Tests and made the last glide flight in the X-24B. McMurtry was Dryden’s Director for Flight Operations from 1986 to 1998, when he became Associate Director for Operations at NASA Dryden. In 1982, McMurtry received the Iven C. Kincheloe Award from the Society of Experimental Test Pilots for his contributions as project pilot on the AD-1 Oblique Wing program. In 1998 he was named as one of the honorees at the Lancaster, Calif., ninth Aerospace Walk of Honor ceremonies. In 1999 he was awarded the NASA Distinguished Service Medal. He retired in 1999 after a distinguished career as pilot and manager at Dryden that began in 1967.

Prospects for spinel-stabilized, high-capacity lithium-ion battery cathodes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Croy, Jason R.; Park, Joong Sun; Shin, Youngho

Herein we report early results on efforts to optimize the electrochemical performance of a cathode composed of a lithium- and manganese-rich “layered-layered-spinel” material for lithium-ion battery applications. Pre-pilot scale synthesis leads to improved particle properties compared with lab-scale efforts, resulting in high capacities (≳200 mAh/g) and good energy densities (>700 Wh/kg) in tests with lithium-ion cells. Subsequent surface modifications give further improvements in rate capabilities and high-voltage stability. These results bode well for advances in the performance of this class of lithium- and manganese-rich cathode materials.

Prospects for spinel-stabilized, high-capacity lithium-ion battery cathodes

DOE PAGES

Croy, Jason R.; Park, Joong Sun; Shin, Youngho; ...

2016-10-13

Herein we report early results on efforts to optimize the electrochemical performance of a cathode composed of a lithium- and manganese-rich “layered-layered-spinel” material for lithium-ion battery applications. Pre-pilot scale synthesis leads to improved particle properties compared with lab-scale efforts, resulting in high capacities (≳200 mAh/g) and good energy densities (>700 Wh/kg) in tests with lithium-ion cells. Subsequent surface modifications give further improvements in rate capabilities and high-voltage stability. These results bode well for advances in the performance of this class of lithium- and manganese-rich cathode materials.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Menon, R.; Grames, L.M.

Pilot Carrousel testing was conducted for about three months on wastewaters generated at a major potato processing facility in 1993. The testing focused toward removal of BOD, NH{sub 3} and NO{sub 3}, and Total-P. After five-six weeks that it took for the system to reach steady state operation, the pilot plant was able to treat the wastewaters quite well. Effluent BOD{sub 5} and TKN values were less than 8 and 4 mg/L, respectively, during the second half of testing. Total-P in the effluent was less than 10 mg/L, although this step was not optimized. Based on the pilot testing, amore » full-scale Carrousel activated sludge plant was designed and commissioned in 1994. This plant is currently treating all the wastewaters from the facility and performing contaminant removals at a very high level.« less

Simulation development and evaluation of an improved longitudinal velocity vector control wheel steering mode and electronic display format

NASA Technical Reports Server (NTRS)

Steinmetz, G. G.

1980-01-01

Using simulation, an improved longitudinal velocity vector control wheel steering mode and an improved electronic display format for an advanced flight system were developed and tested. Guidelines for the development phase were provided by test pilot critique summaries of the previous system. The results include performances from computer generated step column inputs across the full airplane speed and configuration envelope, as well as piloted performance results taken from a reference line tracking task and an approach to landing task conducted under various environmental conditions. The analysis of the results for the reference line tracking and approach to landing tasks indicates clearly detectable improvement in pilot tracking accuracy with a reduction in physical workload. The original objectives of upgrading the longitudinal axis of the velocity vector control wheel steering mode were successfully met when measured against the test pilot critique summaries and the original purpose outlined for this type of augment control mode.

TECHNOLOGY EVALUATION REPORT, SITE PROGRAM DEMONSTRATION TEST: SHIRCO PILOT-SCALE INFRARED INCINERATION SYSTEM ROSE TOWNSHIP DEMODE ROAD SUPERFUND SITE - VOLUME II

EPA Science Inventory

The performance of the Shirco pilot-scale infrared thermal destruction system has been evaluated at the Rose Township, Demode Road Superfund Site and is presented in the report. The waste tested consisted of solvents, organics and heavy metals in an illegal dump site. Volume I gi...

40 CFR 88.204-94 - Sales requirements for the California Pilot Test Program.

Code of Federal Regulations, 2011 CFR

2011-07-01

... equation rounded to the nearest whole number: ER03JA96.003 Where: RMS = a manufacturer's required sales in... 40 Protection of Environment 20 2011-07-01 2011-07-01 false Sales requirements for the California... Sales requirements for the California Pilot Test Program. (a) The total annual required minimum sales...

40 CFR 88.204-94 - Sales requirements for the California Pilot Test Program.

Code of Federal Regulations, 2010 CFR

2010-07-01

... equation rounded to the nearest whole number: ER03JA96.003 Where: RMS = a manufacturer's required sales in... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Sales requirements for the California... Sales requirements for the California Pilot Test Program. (a) The total annual required minimum sales...

40 CFR 88.204-94 - Sales requirements for the California Pilot Test Program.

Code of Federal Regulations, 2013 CFR

2013-07-01

... equation rounded to the nearest whole number: ER03JA96.003 Where: RMS = a manufacturer's required sales in... 40 Protection of Environment 21 2013-07-01 2013-07-01 false Sales requirements for the California... Sales requirements for the California Pilot Test Program. (a) The total annual required minimum sales...

40 CFR 88.204-94 - Sales requirements for the California Pilot Test Program.

Code of Federal Regulations, 2012 CFR

2012-07-01

... equation rounded to the nearest whole number: ER03JA96.003 Where: RMS = a manufacturer's required sales in... 40 Protection of Environment 21 2012-07-01 2012-07-01 false Sales requirements for the California... Sales requirements for the California Pilot Test Program. (a) The total annual required minimum sales...

40 CFR 88.204-94 - Sales requirements for the California Pilot Test Program.

Code of Federal Regulations, 2014 CFR

2014-07-01

... equation rounded to the nearest whole number: ER03JA96.003 Where: RMS = a manufacturer's required sales in... 40 Protection of Environment 20 2014-07-01 2013-07-01 true Sales requirements for the California... Sales requirements for the California Pilot Test Program. (a) The total annual required minimum sales...

40 CFR Appendix - Tables to Subpart B of Part 88

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 21 2012-07-01 2012-07-01 false Tables to Subpart B of Part 88 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CLEAN-FUEL VEHICLES California Pilot Test Program State opt-in for the California Pilot Test Program. Pt. 88, Subpt. B, Tables Tables to Subpart B of Part 88...

40 CFR Appendix - Tables to Subpart B of Part 88

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 21 2013-07-01 2013-07-01 false Tables to Subpart B of Part 88 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CLEAN-FUEL VEHICLES California Pilot Test Program State opt-in for the California Pilot Test Program. Pt. 88, Subpt. B, Tables Tables to Subpart B of Part 88...

40 CFR Appendix - Tables to Subpart B of Part 88

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Tables to Subpart B of Part 88 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CLEAN-FUEL VEHICLES California Pilot Test Program State opt-in for the California Pilot Test Program. Pt. 88, Subpart B, Tables Tables to Subpart B of Part 88...

40 CFR Appendix - Tables to Subpart B of Part 88

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 20 2011-07-01 2011-07-01 false Tables to Subpart B of Part 88 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CLEAN-FUEL VEHICLES California Pilot Test Program State opt-in for the California Pilot Test Program. Pt. 88, Subpart B, Tables Tables to Subpart B of Part 88...

Contextual Emotion-Regulation Therapy for Childhood Depression: Description and Pilot Testing of a New Intervention

ERIC Educational Resources Information Center

Kovacs, Maria; Sherrill, Joel; George, Charles J.; Pollock, Myrna; Tumuluru, Rameshwari V.; Ho, Vincent

2006-01-01

Objective: To pilot test the acceptability and efficacy of contextual emotion-regulation therapy (CERT), a new, developmentally appropriate intervention for childhood depression, which focuses on the self-regulation of dysphoria. Method: Two samples of convenience (n = 29, n = 2) served to verify some CERT constructs; it was then operationalized…

Proofreading as an Index of Crystallised Intelligence

ERIC Educational Resources Information Center

Furnham, Adrian

2010-01-01

This paper reports on four studies that were all concerned with cognitive and non-cognitive correlates of proofreading (PR) ability. A new, five-minute PR test was devised and piloted. In the first pilot study (N = 191) it was correlated with a verbal reasoning test. In the second study (N = 103) PR scores were regressed onto measures of…

Preschool Social-Emotional Skills Training: A Controlled Pilot Test of the Making Choices and Strong Families Programs

ERIC Educational Resources Information Center

Conner, Natalie W.; Fraser, Mark W.

2011-01-01

Objective: The purpose of this study was to pilot test a multicomponent program designed to prevent aggressive behavior in preschool children. The first program component was comprised of social-emotional skills training. It focused on improving the social information processing and emotional-regulation skills of children. The second component was…

Pilot-Testing CATCH Early Childhood: A Preschool-Based Healthy Nutrition and Physical Activity Program

ERIC Educational Resources Information Center

Sharma, Shreela; Chuang, Ru-Jye; Hedberg, Ann Marie

2011-01-01

Background: The literature on theoretically-based programs targeting healthy nutrition and physical activity in preschools is scarce. Purpose: To pilot test CATCH Early Childhood (CEC), a preschool-based nutrition and physical activity program among children ages three to five in Head Start. Methods: The study was conducted in two Head Start…

Pilot Testing for Feasibility in a Study of Student Retention and Attrition in Online Undergraduate Programs

ERIC Educational Resources Information Center

Fraser, Joy; Fahlman, Dorothy; Arscott, Jane; Guillot, Isabelle

2018-01-01

Prior to undertaking a descriptive study on attrition and retention of students in two online undergraduate health administration and human service programs, a pilot test was conducted to assess the procedures for participant recruitment, usability of the survey questionnaire, and data collection processes. A retention model provided the…

Biocarriers Improve Bioaugmentation Efficiency of a Rapid Sand Filter for the Treatment of 2,6-Dichlorobenzamide-Contaminated Drinking Water.

PubMed

Horemans, Benjamin; Raes, Bart; Vandermaesen, Johanna; Simanjuntak, Yanti; Brocatus, Hannelore; T'Syen, Jeroen; Degryse, Julie; Boonen, Jos; Wittebol, Janneke; Lapanje, Ales; Sørensen, Sebastian R; Springael, Dirk

2017-02-07

Aminobacter sp. MSH1 immobilized in an alginate matrix in porous stones was tested in a pilot system as an alternative inoculation strategy to the use of free suspended cells for biological removal of micropollutant concentrations of 2,6-dichlorobenzamide (BAM) in drinking water treatment plants (DWTPs). BAM removal rates and MSH1 cell numbers were recorded during operation and assessed with specific BAM degradation rates obtained in lab conditions using either freshly grown cells or starved cells to explain reactor performance. Both reactors inoculated with either suspended or immobilized cells showed immediate BAM removal under the threshold of 0.1 μg/L, but the duration of sufficient BAM removal was 2-fold (44 days) longer for immobilized cells. The longer sufficient BAM removal in case of immobilized cells compared to suspended cells was mainly explained by a lower initial loss of MSH1 cells at operational start due to volume replacement and shear. Overall loss of activity in the reactors though was due to starvation, and final removal rates did not differ between reactors inoculated with immobilized and suspended cells. Management of assimilable organic carbon, in addition to cell immobilization, appears crucial for guaranteeing long-term BAM degradation activity of MSH1 in DWTP units.

Evaluation of Piloted Inputs for Onboard Frequency Response Estimation

NASA Technical Reports Server (NTRS)

Grauer, Jared A.; Martos, Borja

2013-01-01

Frequency response estimation results are presented using piloted inputs and a real-time estimation method recently developed for multisine inputs. A nonlinear simulation of the F-16 and a Piper Saratoga research aircraft were subjected to different piloted test inputs while the short period stabilator/elevator to pitch rate frequency response was estimated. Results show that the method can produce accurate results using wide-band piloted inputs instead of multisines. A new metric is introduced for evaluating which data points to include in the analysis and recommendations are provided for applying this method with piloted inputs.

Family Caregivers for Veterans with Spinal Cord Injury: Exploring the Stresses and Benefits

DTIC Science & Technology

2017-12-01

testing of the newly developed instrument was conducted, however, the sample size was smaller than needed for full pilot testing. A future study with a...larger sample will be needed to verify the pilot testing results. 15. SUBJECT TERMS spinal cord injury, veterans, caregivers 16. SECURITY...A qualitative approach takes advantage of the rich information provided by those living the experience of caregiving and SCI, enabling us to learn

The Shock and Vibration Bulletin. Part 3. Aerospace Vehicles, Vibro-acoustics

DTIC Science & Technology

1975-06-01

Corporation, San Diego, California .ANALYSIS AND FLIGHIT TEST CORRELATION OF VIBROACOUS’IIC ENVIRONMENTS ON A REMOTELY PILOTED VEHIICLE... piloted aircraft shown in tic set of specifications calls for extensive flight Figure 1. It is powered by a single, fuselage- test data encompassing the...Company, Hamptnn Virginia c1 DETERMINAf ION OF PROPELLATNT EFFECTIVE MASS PROPERTIES USING MODAL TEST DATAj 15 J. C. Chen and J,. A Garba, Jet Propulsion

Early language screening in city and Hackney: the concurrent validity of a measure designed for use with 2 1/2-year-olds.

PubMed

Law, J

1994-01-01

This paper reports data relating to the development of a screening test for language impairment in 2 1/2-year-old children. The screening test itself has previously been described. The results of a pilot study and a larger community study are reported. In all, 34 children were included in the pilot study and 1015 in the community study. The reference test selected was the Reynell Developmental Language Scales and the cut-off adopted 1.5 standard deviations below the mean for either the expressive or the receptive scale of the test concerned. The pass mark on the screening test was ascertained using receiver operating characteristics (ROC). The validity is reported given the cut-off identified. The specificity, sensitivity and both positive and negative predictive abilities are reported for both the pilot and the subsequent study. The application of the test is discussed in the context of the current debate about early identification.

Multi-Axis Test Facility

NASA Image and Video Library

1959-11-01

Multi-Axis Test Facility, Space Progress Report, November 1, 1959: The Multi Axis Space Test Inertia Facility [MASTIF], informally referred to as the Gimbal Rig, was installed inside the Altitude Wind Tunnel. The rig, which spun on three axis simultaneously, was used to train the Mercury astronauts on how to bring a spinning spacecraft under control and to determine the effects of rapid spinning on the astronaut's eyesight and psyche. Small gaseous nitrogen jets were operated by the pilot to gain control of the rig after it had been set in motion. Part 1 shows pilot Joe Algranti in the rig as it rotates over one, two, and three axis. It also has overall views of the test set-up with researchers and technicians on the test platform. Part 2 shows Algranti being secured in the rig prior to the test. The rig is set in motion and the pilot slowly brings it under control. The Mercury astronauts trained on the MASTIF in early spring of 1960.

Ride qualities criteria validation/pilot performance study: Flight test results

NASA Technical Reports Server (NTRS)

Nardi, L. U.; Kawana, H. Y.; Greek, D. C.

1979-01-01

Pilot performance during a terrain following flight was studied for ride quality criteria validation. Data from manual and automatic terrain following operations conducted during low level penetrations were analyzed to determine the effect of ride qualities on crew performance. The conditions analyzed included varying levels of turbulence, terrain roughness, and mission duration with a ride smoothing system on and off. Limited validation of the B-1 ride quality criteria and some of the first order interactions between ride qualities and pilot/vehicle performance are highlighted. An earlier B-1 flight simulation program correlated well with the flight test results.

Piloted Parameter Identification Flight Test Maneuvers for Closed Loop Modeling of the F-18 High Alpha Research Vehicle (HARV)

NASA Technical Reports Server (NTRS)

Morelli, Eugene A.

1996-01-01

Flight test maneuvers are specified for the F-18 High Alpha Research Vehicle (HARV). The maneuvers were designed for closed loop parameter identification purposes, specifically for longitudinal and lateral linear model parameter estimation at 5, 20, 30, 45, and 60 degrees angle of attack, using the NASA 1A control law. Each maneuver is to be realized by the pilot applying square wave inputs to specific pilot station controls. Maneuver descriptions and complete specifications of the time/amplitude points defining each input are included, along with plots of the input time histories.

Proteus DSA control room in Mojave, CA

NASA Image and Video Library

2003-04-03

Proteus DSA control room in Mojave, CA (L to R) Jean-Pierre Soucy; Amphitech International Software engineer Craig Bomben; NASA Dryden Test Pilot Pete Siebold; (with headset, at computer controls) Scaled Composites pilot Bob Roehm; New Mexico State University (NMSU) UAV Technical Analysis Application Center (TAAC) Chuck Coleman; Scaled Composites Pilot Kari Sortland; NMSU TAAC Russell Wolfe; Modern Technology Solutions, Inc. Scaled Composites' unique tandem-wing Proteus was the testbed for a series of UAV collision-avoidance flight demonstrations. An Amphitech 35GHz radar unit installed below Proteus' nose was the primary sensor for the Detect, See and Avoid tests.

Performance evaluation of intermediate cover soil barrier for removal of heavy metals in landfill leachate.

PubMed

Suzuki, Kazuyuki; Anegawa, Aya; Endo, Kazuto; Yamada, Masato; Ono, Yusaku; Ono, Yoshiro

2008-11-01

This pilot-scale study evaluated the use of intermediate cover soil barriers for removing heavy metals in leachate generated from test cells for co-disposed fly ash from municipal solid waste incinerators, ash melting plants, and shredder residue. Cover soil barriers were mixtures of Andisol (volcanic ash soil), waste iron powder, (grinder dust waste from iron foundries), and slag fragments. The cover soil barriers were installed in the test cells' bottom layer. Sorption/desorption is an important process in cover soil bottom barrier for removal of heavy metals in landfill leachate. Salt concentrations such as those of Na, K, and Ca in leachate were extremely high (often greater than 30 gL(-1)) because of high salt content in fly ash from ash melting plants. Concentrations of all heavy metals (nickel, manganese, copper, zinc, lead, and cadmium) in test cell leachates with a cover soil barrier were lower than those of the test cell without a cover soil barrier and were mostly below the discharge limit, probably because of dilution caused by the amount of leachate and heavy metal removal by the cover soil barrier. The cover soil barriers' heavy metal removal efficiency was calculated. About 50% of copper, nickel, and manganese were removed. About 20% of the zinc and boron were removed, but lead and cadmium were removed only slightly. Based on results of calculation of the Langelier saturation index and analyses of core samples, the reactivity of the cover soil barrier apparently decreases because of calcium carbonate precipitation on the cover soil barriers' surfaces.

Testing Telephone and Web Surveys for Studying Men's Sexual Assault Perpetration Behaviors

ERIC Educational Resources Information Center

DiNitto, Diana M.; Busch-Armendariz, Noel Bridget; Bender, Kimberly; Woo, Hyeyoung; Tackett-Gibson, Melissa; Dyer, James

2008-01-01

Three pilot studies were conducted to obtain information about sexual assault perpetration from adult men in the United States. Each used the same random digit-dial sampling and recruitment strategy. One pilot was administered by telephone and two via the Web. Response rates in all pilots were low. Although results cannot be generalized beyond the…

Preparing Pilots for Takeoff

ERIC Educational Resources Information Center

Ravage, Barbara

2012-01-01

Why would schools consider partnering with a vendor to operate a pilot? Why not just wait until the final product is released? For starters, pilots provide schools with a golden opportunity to get an early look at the software, take it for a test flight, and ask for changes tailored to their operating environment and business needs. In some cases,…

78 FR 57786 - Airworthiness Directives; AgustaWestland S.p.A. Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-20

... to ensure that the windows are properly bonded within the doors. If the windows are not properly bonded, the AD requires applying bonding to the windows, the seals, and the window frames of the pilot and co-pilot doors. This AD was prompted by the loss of a pilot-door window during a test flight. The...

Flight Instructor-Student Pilot Perceptive Similarity and Its Effect on Flight Training Time.

ERIC Educational Resources Information Center

Kreienkamp, Ronald A.

This study attempts to identify factors that may contribute to the learning process of the student pilot in order to lower flight costs while maintaining or increasing safety factors. Specifically, it tests the hypothesis that a significant relationship exists between the similarity of flight instructor and student pilot perceptive styles and the…

The effects of workload on respiratory variables in simulated flight: a preliminary study.

PubMed

Karavidas, Maria Katsamanis; Lehrer, Paul M; Lu, Shou-En; Vaschillo, Evgeny; Vaschillo, Bronya; Cheng, Andrew

2010-04-01

In this pilot study, we investigated respiratory activity and end-tidal carbon dioxide (P(et)CO(2)) during exposure to varying levels of work load in a simulated flight environment. Seven pilots (age: 34-60) participated in a one-session test on the Boeing 737-800 simulator. Physiological data were collected while pilots wore an ambulatory multi-channel recording device. Respiratory variables, including inductance plethysmography (respiratory pattern) and pressure of end-tidal carbon dioxide (P(et)CO(2)), were collected demonstrating change in CO(2) levels proportional to changes in flight task workload. Pilots performed a set of simulation flight tasks. Pilot performance was rated for each task by a test pilot; and self-report of workload was taken using the NASA-TLX scale. Mixed model analysis revealed that respiration rate and minute ventilation are significantly associated with workload levels and evaluator scores controlling for "vanilla baseline" condition. Hypocapnia exclusively occurred in tasks where pilots performed more poorly. This study was designed as a preliminary investigation in order to develop a psychophysiological assessment methodology, rather than to offer conclusive findings. The results show that the respiratory system is very reactive to high workload conditions in aviation and suggest that hypocapnia may pose a flight safety risk under some circumstances. Copyright © 2010 Elsevier B.V. All rights reserved.

Cell-Mediated Immunity to Target the Persistent Human Immunodeficiency Virus Reservoir

PubMed Central

Montaner, Luis J.

2017-01-01

Abstract Effective clearance of virally infected cells requires the sequential activity of innate and adaptive immunity effectors. In human immunodeficiency virus (HIV) infection, naturally induced cell-mediated immune responses rarely eradicate infection. However, optimized immune responses could potentially be leveraged in HIV cure efforts if epitope escape and lack of sustained effector memory responses were to be addressed. Here we review leading HIV cure strategies that harness cell-mediated control against HIV in stably suppressed antiretroviral-treated subjects. We focus on strategies that may maximize target recognition and eradication by the sequential activation of a reconstituted immune system, together with delivery of optimal T-cell responses that can eliminate the reservoir and serve as means to maintain control of HIV spread in the absence of antiretroviral therapy (ART). As evidenced by the evolution of ART, we argue that a combination of immune-based strategies will be a superior path to cell-mediated HIV control and eradication. Available data from several human pilot trials already identify target strategies that may maximize antiviral pressure by joining innate and engineered T cell responses toward testing for sustained HIV remission and/or cure. PMID:28520969

Validation and cross-cultural pilot testing of compliance with standard precautions scale: self-administered instrument for clinical nurses.

PubMed

Lam, Simon C

2014-05-01

To perform detailed psychometric testing of the compliance with standard precautions scale (CSPS) in measuring compliance with standard precautions of clinical nurses and to conduct cross-cultural pilot testing and assess the relevance of the CSPS on an international platform. A cross-sectional and correlational design with repeated measures. Nursing students from a local registered nurse training university, nurses from different hospitals in Hong Kong, and experts in an international conference. The psychometric properties of the CSPS were evaluated via internal consistency, 2-week and 3-month test-retest reliability, concurrent validation, and construct validation. The cross-cultural pilot testing and relevance check was examined by experts on infection control from various developed and developing regions. Among 453 participants, 193 were nursing students, 165 were enrolled nurses, and 95 were registered nurses. The results showed that the CSPS had satisfactory reliability (Cronbach α = 0.73; intraclass correlation coefficient, 0.79 for 2-week test-retest and 0.74 for 3-month test-retest) and validity (optimum correlation with criterion measure; r = 0.76, P < .001; satisfactory results on known-group method and hypothesis testing). A total of 19 experts from 16 countries assured that most of the CSPS findings were relevant and globally applicable. The CSPS demonstrated satisfactory results on the basis of the standard international criteria on psychometric testing, which ascertained the reliability and validity of this instrument in measuring the compliance of clinical nurses with standard precautions. The cross-cultural pilot testing further reinforced the instrument's relevance and applicability in most developed and developing regions.

Influence of Cultural, Organizational, and Automation Capability on Human Automation Trust: A Case Study of Auto-GCAS Experimental Test Pilots

NASA Technical Reports Server (NTRS)

Koltai, Kolina; Ho, Nhut; Masequesmay, Gina; Niedober, David; Skoog, Mark; Cacanindin, Artemio; Johnson, Walter; Lyons, Joseph

2014-01-01

This paper discusses a case study that examined the influence of cultural, organizational and automation capability upon human trust in, and reliance on, automation. In particular, this paper focuses on the design and application of an extended case study methodology, and on the foundational lessons revealed by it. Experimental test pilots involved in the research and development of the US Air Force's newly developed Automatic Ground Collision Avoidance System served as the context for this examination. An eclectic, multi-pronged approach was designed to conduct this case study, and proved effective in addressing the challenges associated with the case's politically sensitive and military environment. Key results indicate that the system design was in alignment with pilot culture and organizational mission, indicating the potential for appropriate trust development in operational pilots. These include the low-vulnerability/ high risk nature of the pilot profession, automation transparency and suspicion, system reputation, and the setup of and communications among organizations involved in the system development.

Enabling CSPA Operations Through Pilot Involvement in Longitudinal Approach Spacing

NASA Technical Reports Server (NTRS)

Battiste, Vernol (Technical Monitor); Pritchett, Amy

2003-01-01

Several major airports around the United States have, or plan to have, closely-spaced parallel runways. This project complemented current and previous research by examining the pilots ability to control their position longitudinally within their approach stream.This project s results considered spacing for separation from potential positions of wake vortices from the parallel approach. This preventive function could enable CSPA operations to very closely spaced runways. This work also considered how pilot involvement in longitudinal spacing could allow for more efficient traffic flow, by allowing pilots to keep their aircraft within tighter arrival slots then air traffic control (ATC) might be able to establish, and by maintaining space within the arrival stream for corresponding departure slots. To this end, this project conducted several research studies providing an analytic and computational basis for calculating appropriate aircraft spacings, experimental results from a piloted flight simulator test, and an experimental testbed for future simulator tests. The following sections summarize the results of these three efforts.

A pilot's subjective analysis of a Cockpit Display of Traffic Information (CDTI). [terminal configured vehicle

NASA Technical Reports Server (NTRS)

Keyser, G. L., Jr.

1981-01-01

Both the advent of electronic displays for cockpit applications and the availability of high-capacity data transmission systems, linking aicraft with ATC ground computers, offer the opportunity of expanding the pilots' role in the distributive management process. A critical element in this process is believed to be the presentation to the pilot of his traffic situation. A representative cockpit display of traffic information (CDTI) system is presented as viewed from the pilot in the cockpit, and the research results from flight tests presented. The use of advanced controls and displays allows for presentation to the pilot, large quantities of information that he has not had before. The real challenge in the design of an operational CDTI system will be the satisfaction of needs for information and the presentation of all necessary information, only in a useable format in order to avoid clutter. Even though a reasonably large display was utilized in these tests, display clutter was the primary problem from the standpoint of information assimilation.

Safety, humoral and cell-mediated immune responses to herpes zoster vaccine in subjects with diabetes mellitus.

PubMed

Hata, Atsuko; Inoue, Fukue; Yamasaki, Midori; Fujikawa, Jun; Kawasaki, Yukiko; Hamamoto, Yoshiyuki; Honjo, Sachiko; Moriishi, Eiko; Mori, Yasuko; Koshiyama, Hiroyuki

2013-09-01

To evaluate varicella zoster virus-specific cell-mediated immunity and humoral immunogenicity against the herpes zoster vaccine, which is licensed as the Live Varicella Vaccine (Oka Strain) in Japan, in elderly people with or without diabetes mellitus. A pilot study was conducted between May 2010 and November 2010 at Kitano Hospital, a general hospital in the city of Osaka in Japan. A varicella skin test, interferon-gamma enzyme-linked immunospot assay and immunoadherence hemagglutination tests were performed 0, 3, and 6 months after vaccination. Vaccine safety was also assessed using questionnaires for 42 days and development of zoster during the one-year observational period. We enrolled 10 healthy volunteers and 10 patients with diabetes mellitus aged 60-70 years. The live herpes zoster vaccine boosted virus-specific, cell-mediated and humoral immunity between elderly people, with or without diabetes. Moreover, no systemic adverse reaction was found. None of the study participants developed herpes zoster. The live herpes zoster vaccine was used safely. It effectively enhanced specific immunity to varicella zoster virus in older people with or without diabetes mellitus. Copyright © 2013 The British Infection Association. Published by Elsevier Ltd. All rights reserved.

Pilot-scale cultivation of wall-deficient transgenic Chlamydomonas reinhardtii strains expressing recombinant proteins in the chloroplast.

PubMed

Zedler, Julie A Z; Gangl, Doris; Guerra, Tiago; Santos, Edgar; Verdelho, Vitor V; Robinson, Colin

2016-08-01

Microalgae have emerged as potentially powerful platforms for the production of recombinant proteins and high-value products. Chlamydomonas reinhardtii is a potentially important host species due to the range of genetic tools that have been developed for this unicellular green alga. Transformation of the chloroplast genome offers important advantages over nuclear transformation, and a wide range of recombinant proteins have now been expressed in the chloroplasts of C. reinhardtii strains. This is often done in cell wall-deficient mutants that are easier to transform. However, only a single study has reported growth data for C. reinhardtii grown at pilot scale, and the growth of cell wall-deficient strains has not been reported at all. Here, we report the first pilot-scale growth study for transgenic, cell wall-deficient C. reinhardtii strains. Strains expressing a cytochrome P450 (CYP79A1) or bifunctional diterpene synthase (cis-abienol synthase, TPS4) were grown for 7 days under mixotrophic conditions in a Tris-acetate-phosphate medium. The strains reached dry cell weights of 0.3 g/L within 3-4 days with stable expression levels of the recombinant proteins during the whole upscaling process. The strains proved to be generally robust, despite the cell wall-deficient phenotype, but grew poorly under phototrophic conditions. The data indicate that cell wall-deficient strains may be highly amenable for transformation and suitable for commercial-scale operations under mixotrophic growth regimes.

Nils Larson

NASA Image and Video Library

2007-03-16

Nils Larson is a research pilot in the Flight Crew Branch of NASA's Dryden Flight Research Center, Edwards, Calif. Larson joined NASA in February 2007 and will fly the F-15, F-18, T-38 and ER-2. Prior to joining NASA, Larson was on active duty with the U.S. Air Force. He has accumulated more that 4,900 hours of military and civilian flight experience in more than 70 fixed and rotary winged aircraft. Larson completed undergraduate pilot training at Williams Air Force Base, Chandler, Ariz., in 1987. He remained at Williams as a T-37 instructor pilot. In 1991, Larson was assigned to Beale Air Force Base, Calif., as a U-2 pilot. He flew 88 operational missions from Korea, Saudi Arabia, the United Kingdom, Panama and other locations. Larson graduated from the U.S. Air Force Test Pilot School at Edwards Air Force Base, Calif., in Class 95A. He became a flight commander and assistant operations officer for the 445th squadron at Edwards. He flew the radar, avionics integration and engine tests in F-15 A-D, the early flights of the glass cockpit T-38C and airworthiness flights of the Coast Guard RU-38. He was selected to serve as an Air Force exchange instructor at the U.S. Naval Test Pilot School, Patuxent River, Md. He taught systems and fixed-wing flight test and flew as an instructor pilot in the F-18, T-2, U-6A Beaver and X-26 Schweizer sailplane. Larson commanded U-2 operations for Warner Robins Air Logistics Center's Detachment 2 located in Palmdale, Calif. In addition to flying the U-2, Larson supervised the aircraft's depot maintenance and flight test. He was the deputy group commander for the 412th Operations Group at Edwards before retiring from active duty in 2007 with the rank of lieutenant colonel. His first experience with NASA was at the Glenn Research Center, Cleveland, where he served a college summer internship working on arcjet engines. Larson is a native of Bethany, W.Va,, and received his commission from the U.S. Air Force Academy in 1986 with a

Pre-Study Walkthrough with a Commercial Pilot for a Preliminary Single Pilot Operations Experiment

NASA Technical Reports Server (NTRS)

O'Connor-Dreher, Ryan; Roberts, Z.; Ziccardi, J.; Vu, K-P. L.; Strybel, T.; Koteskey, Robert William; Lachter, Joel B.; Vi Dao, Quang; Johnson, Walter W.; Battiste, V.

2013-01-01

The number of crew members in commercial flights has decreased to two members, down from the five-member crew required 50 years ago. One question of interest is whether the crew should be reduced to one pilot. In order to determine the critical factors involved in safely transitioning to a single pilot, research must examine whether any performance deficits arise with the loss of a crew member. With a concrete understanding of the cognitive and behavioral role of a co-pilot, aeronautical technologies and procedures can be developed that make up for the removal of the second aircrew member. The current project describes a pre-study walkthrough process that can be used to help in the development of scenarios for testing future concepts and technologies for single pilot operations. Qualitative information regarding the tasks performed by the pilots can be extracted with this technique and adapted for future investigations of single pilot operations.

Coherence-controlled holographic microscopy enabled recognition of necrosis as the mechanism of cancer cells death after exposure to cytopathic turbid emulsion

NASA Astrophysics Data System (ADS)

Collakova, Jana; Krizova, Aneta; Kollarova, Vera; Dostal, Zbynek; Slaba, Michala; Vesely, Pavel; Chmelik, Radim

2015-11-01

Coherence-controlled holographic microscopy (CCHM) in low-coherence mode possesses a pronounced coherence gate effect. This offers an option to investigate the details of cellular events leading to cell death caused by cytopathic turbid emulsions. CCHM capacity was first assessed in model situations that showed clear images obtained with low coherence of illumination but not with high coherence of illumination. Then, the form of death of human cancer cells induced by treatment with biologically active phospholipids (BAPs) preparation was investigated. The observed overall retraction of cell colony was apparently caused by the release of cell-to-substratum contacts. This was followed by the accumulation of granules decorating the nuclear membrane. Then, the occurrence of nuclear membrane indentations signaled the start of damage to the integrity of the cell nucleus. In the final stage, cells shrunk and disintegrated. This indicated that BAPs cause cell death by necrosis and not apoptosis. An intriguing option of checking the fate of cancer cells caused by the anticipated cooperative effect after adding another tested substance sodium dichloroacetate to turbid emulsion is discussed on grounds of pilot experiments. Such observations should reveal the impact and mechanism of action of the interacting drugs on cell behavior and fate that would otherwise remain hidden in turbid milieu.

STS-93 Pilot Ashby works with the STL-B experiment on the middeck

NASA Image and Video Library

2013-11-18

STS093-319-029 (23-27 July 1999) --- Astronaut Jeffrey S. Ashby, pilot, works with the Space Tissue Loss-B experiment on Columbia's middeck. The experiment is set up to observe cells in culture with a video microscope imaging system to record near-real-time interactions of detecting and inducing cellular responses (macromorphological changes).

Cellular Phone Use in Class: Implications for Teaching and Learning a Pilot Study

ERIC Educational Resources Information Center

Burns, Shari M.; Lohenry, Kevin

2010-01-01

Students equipped with the cell phones enter college classrooms daily. Realizing the impact of technology on fellow learners and faculty represents an area of concern. A pilot study was conducted to determine student and faculty perception regarding cellular phone use in the classroom. A quantitative descriptive study examined the perception of…

40 CFR 63.9075 - What definitions apply to this subpart?

Code of Federal Regulations, 2011 CFR

2011-07-01

... using either mercury cells, diaphragm cells, or membrane cells. Continuous monitoring system, for... is discarded from an HCl production facility. Plant site means all contiguous or adjoining property... and pilot plant operations whose primary purpose is to conduct research and development into new...

NACA Pilots at the Aircraft Engine Research Laboratory

NASA Image and Video Library

1945-07-21

The Aircraft Engine Research Laboratory’s pilot corps during the final days of World War II: from left to right, Joseph Vensel, Howard Lilly, William Swann, and Joseph Walker. William “Eb” Gough joined the group months after this photograph. These men were responsible for flying the various National Advisory Committee for Aeronautics (NACA) aircraft to test new engine modifications, study ice buildup, and determine fuel performance. Vensel, a veteran pilot from Langley, was the Chief of Flight Operations and a voice of reason at the laboratory. In April 1947 Vensel was transferred to lead the new Muroc Flight Tests Unit in California until 1966. Lilly was a young pilot with recent Navy experience. Lilly also flew in the 1946 National Air Races. He followed Vensel to Muroc in July 1947 where he became the first NACA pilot to penetrate the sound barrier. On May 3, 1948, Lilly became the first NACA pilot to die in the line of duty. Swann was a young civilian pilot when he joined the NACA. He spent his entire career at the Cleveland laboratory, and led the flight operations group from the early 1960s until 1979. Two World War II veterans joined the crew after the war. Walker was a 24-year-old P–38 reconnaissance pilot. He joined the NACA as a physicist in early 1945 but soon worked his way into the cadre of pilots. Walker later gained fame as an X-plane pilot at Muroc and was killed in a June 1966 fatal crash. Gough survived being shot down twice during the war and was decorated for flying rescue missions in occupied areas.

Multi-Axis Test Facility Orientation

NASA Image and Video Library

1960-03-01

Seven Astronauts and William North undergo Multi Axis Space Test Inertia Facility (MASTIF) orientation: This film contains footage Gus Grissom leaving "Astro-Penthouse" and beginning tests, pilot Joe Algranti explaining the MASTIF to Scott Carpenter, Walter Schirra testing the controls and being strapped in, Deke Slayton climbing into the rig, and John Glenn preparing for test and being briefed by Algranti. Also seen are Alan Shepherd talking with Algranti and James Useller prior to climbing into rig and beginning test, Gordon Cooper being strapped in and beginning his test, Cooper and Algranti briefing to William North prior to his test. North was a test pilot on the NASA committee which selected the Mercury 7 astronauts.

Possible influence of infrasound on glioma cell response to chemotherapy: a pilot study.

PubMed

Yount, Garret; Taft, Ryan; West, Jeremy; Moore, Dan

2004-04-01

To assess the response of cultured human tumor cells to infrasound in combination with conventional anticancer agents using an infrasound-emitting apparatus marketed as a therapeutic device. Two pilot experiments measured proliferation of cultured brain tumor cells exposed to three treatment conditions: infrasound emission alone, infrasound in combination with the chemotherapy 5-fluorouracil (5-FU), and infrasound in combination with ionizing radiation. Results from each experimental condition were compared to those from appropriate control conditions. A standard colony-forming efficiency assay was used to assess tumor cell proliferation. Tumor cell proliferation was not significantly altered by treatment with infrasound alone, nor did infrasound appear to influence cellular response to x-rays. There was a significant interaction between 5-FU and infrasound (P < 0.0001), however, evident in decreased colony formation. Further research is warranted to assess potential synergism between infrasound and 5-FU against tumor cell proliferation, and to investigate the possible therapeutic use of infrasound.

Development of an improved high efficiency thin silicon solar cell

NASA Technical Reports Server (NTRS)

Lindmayer, J.

1978-01-01

Efforts were concerned with optimizing techniques for thinning silicon slices in NaOH etches, initial investigations of surface texturing, variation of furnace treatments to improve cell efficiency, initial efforts on optimization of gridline and cell sizes and Pilot Line fabrication of quantities of 2 cm x 2 cm 50 micron thick cells.

Dietary Interventions in Multiple Sclerosis: Development and Pilot-Testing of an Evidence Based Patient Education Program

PubMed Central

Riemann-Lorenz, Karin; Eilers, Marlene; von Geldern, Gloria; Schulz, Karl-Heinz; Köpke, Sascha; Heesen, Christoph

2016-01-01

Background Dietary factors have been discussed to influence risk or disease course of multiple sclerosis (MS). Specific diets are widely used among patients with MS. Objective To design and pilot-test an evidence based patient education program on dietary factors in MS. Methods We performed a systematic literature search on the effectiveness of dietary interventions in MS. A web-based survey among 337 patients with MS and 136 healthy controls assessed knowledge, dietary habits and information needs. An interactive group education program was developed and pilot-tested. Results Fifteen randomised-controlled trials (RCTs) were included in the systematic review. Quality of evidence was low and no clear benefit could be seen. Patients with MS significantly more often adhered to a `Mediterranean Diet`(29.7% versus 14.0%, p<0.001) compared to controls. 143 (42%) of the patients with MS had tried special MS diets. Important information needs addressed effectiveness of MS diets (44%) and relation between nutrition and MS (43%). A pilot test of our newly developed patient education program with 13 participants showed excellent comprehensibility and the MS-specific content was judged as very important. However, the poor evidence base for dietary approaches in MS was perceived disappointing. Conclusions Development and pilot-testing of an evidence-based patient education program on nutrition and MS is feasible. Patient satisfaction with the program suffers from the lack of evidence. Further research should focus on generating evidence for the potential influence of lifestyle habits (diet, physical activity) on MS disease course thus meeting the needs of patients with MS. PMID:27764237

Development and Pilot-Testing of a Cognitive Behavioral Coping Skills Group Intervention for Patients with Chronic Hepatitis C.

PubMed

Evon, Donna M; Golin, Carol E; Ruffin, Rachel; Fried, Michael W

2017-06-01

Psychosocial interventions for patients with chronic hepatitis C viral (HCV) infection are needed to attenuate the impact of extrahepatic symptoms, comorbid conditions, and treatment side effects on HCV health outcomes. We adapted empirically-supported interventions for similar patient populations to develop a Cognitive Behavioral Coping Skills group intervention for HCV patients (CBCS-HCV) undergoing treatment. The objectives of this paper are to describe the research activities associated with CBCS-HCV development and pilot testing, including: (1) formative work leading to intervention development; (2) preliminary study protocol; and (3) pilot feasibility testing of the intervention and study design. Formative work included a literature review, qualitative interviews, and adaption, development, and review of study materials. A preliminary study protocol is described. We evaluate the feasibility of conducting a randomized controlled trial (RCT) of the CBCS-HCV with 12 study participants in Wave 1 testing to examine: (a) feasibility of intervention delivery; (b) patient acceptability; (c) recruitment, enrollment, retention; (d) feasibility of conducting a RCT; (d) therapist protocol fidelity; and (e) feasibility of data collection. Numerous lessons were learned. We found very high rates of data collection, participant attendance, engagement, retention and acceptability, and therapist protocol fidelity. We conclude that many aspects of the CBCS-HCV intervention and study protocol were highly feasible. The greatest challenge during this Wave 1 pilot study was efficiency of participant enrollment due to changes in standard of care treatment. These findings informed two additional waves of pilot testing to examine effect sizes and potential improvements in clinical outcomes, with results forthcoming.

Dietary Interventions in Multiple Sclerosis: Development and Pilot-Testing of an Evidence Based Patient Education Program.

PubMed

Riemann-Lorenz, Karin; Eilers, Marlene; von Geldern, Gloria; Schulz, Karl-Heinz; Köpke, Sascha; Heesen, Christoph

2016-01-01

Dietary factors have been discussed to influence risk or disease course of multiple sclerosis (MS). Specific diets are widely used among patients with MS. To design and pilot-test an evidence based patient education program on dietary factors in MS. We performed a systematic literature search on the effectiveness of dietary interventions in MS. A web-based survey among 337 patients with MS and 136 healthy controls assessed knowledge, dietary habits and information needs. An interactive group education program was developed and pilot-tested. Fifteen randomised-controlled trials (RCTs) were included in the systematic review. Quality of evidence was low and no clear benefit could be seen. Patients with MS significantly more often adhered to a `Mediterranean Diet`(29.7% versus 14.0%, p<0.001) compared to controls. 143 (42%) of the patients with MS had tried special MS diets. Important information needs addressed effectiveness of MS diets (44%) and relation between nutrition and MS (43%). A pilot test of our newly developed patient education program with 13 participants showed excellent comprehensibility and the MS-specific content was judged as very important. However, the poor evidence base for dietary approaches in MS was perceived disappointing. Development and pilot-testing of an evidence-based patient education program on nutrition and MS is feasible. Patient satisfaction with the program suffers from the lack of evidence. Further research should focus on generating evidence for the potential influence of lifestyle habits (diet, physical activity) on MS disease course thus meeting the needs of patients with MS.

Mechanisms and kinetics of cellulose fermentation for protein production

NASA Technical Reports Server (NTRS)

Dunlap, C. A.

1971-01-01

The development of a process (and ancillary processing and analytical techniques) to produce bacterial single-cell protein of good nutritional quality from waste cellulose is discussed. A fermentation pilot plant and laboratory were developed and have been in operation for about two years. Single-cell protein (SCP) can be produced from sugarcane bagasse--a typical agricultural cellulosic waste. The optimization and understanding of this process and its controlling variables are examined. Both batch and continuous fermentation runs have been made under controlled conditions in the 535 liter pilot plant vessel and in the laboratory 14-liter fermenters.

Terrain Portrayal for Head-Down Displays Experiment

NASA Technical Reports Server (NTRS)

Hughes, Monica F.; Takallu, M. A.

2002-01-01

The General Aviation Element of the Aviation Safety Program's Synthetic Vision Systems (SVS) Project is developing technology to eliminate low visibility induced General Aviation (GA) accidents. SVS displays present computer generated 3-dimensional imagery of the surrounding terrain on the Primary Flight Display (PFD) to greatly enhance pilot's situation awareness (SA), reducing or eliminating Controlled Flight into Terrain, as well as Low-Visibility Loss of Control accidents. SVS-conducted research is facilitating development of display concepts that provide the pilot with an unobstructed view of the outside terrain, regardless of weather conditions and time of day. A critical component of SVS displays is the appropriate presentation of terrain to the pilot. An experimental study has been conducted at NASA Langley Research Center (LaRC) to explore and quantify the relationship between the realism of the terrain presentation and resulting enhancements of pilot SA and pilot performance. Composed of complementary simulation and flight test efforts, Terrain Portrayal for Head-Down Displays (TP-HDD) experiments will help researchers evaluate critical terrain portrayal concepts. The experimental effort is to provide data to enable design trades that optimize SVS applications, as well as develop requirements and recommendations to facilitate the certification process. This paper focuses on the experimental set-up and preliminary qualitative results of the TP-HDD simulation experiment. In this experiment a fixed based flight simulator was equipped with various types of Head Down flight displays, ranging from conventional round dials (typical of most GA aircraft) to glass cockpit style PFD's. The variations of the PFD included an assortment of texturing and Digital Elevation Model (DEM) resolution combinations. A test matrix of 10 terrain display configurations (in addition to the baseline displays) were evaluated by 27 pilots of various backgrounds and experience levels. Qualitative (questionnaires) and quantitative (pilot performance and physiological) data were collected during the experimental runs. Preliminary results indicate that all of the evaluation pilots favored SVS displays over standard gauges, in terms of terrain awareness, SA, and perceived pilot performance. Among the terrain portrayal concepts tested, most pilots preferred the higher-resolution DEM. In addition, with minimal training, low-hour VFR evaluation pilots were able to negotiate a precision approach using SVS displays with a tunnel in the sky guidance concept.

Occupational Stress and Hypertension among Railway Loco Pilots and Section Controllers.

PubMed

Jayakumar, Devasigamoney

2017-01-01

A cross-sectional study on occupational stress was conducted on loco pilots in 2008, in view of loco pilots being one of the high strain jobs in Indian Railways. Subsequently, a comparative cross-sectional study on occupational stress was conducted among section controllers in 2011, which is another high strain job of Indian Railways. The studies were conducted to analyze and compare occupational stress and hypertension. A cross-sectional study on occupational stress and hypertension was conducted among 230 loco pilots in 2008, and subsequently, a comparative cross-sectional study was conducted among 82 section controllers in 2011. A closed end 24 item questionnaire on occupational stress was administered. Systolic blood pressure above 140 mmHg and diastolic blood pressure above 90 mmHg were considered as hypertension as per the VII Joint National Committee. Chi-square test and t -test were used for testing significance at P < 0.05. The mean stress score was 8.56 in loco pilots and 7.32 in section controllers. The number of loco pilots with more than 12 stress factors was 49 (21.3%) and the number of section controllers with more than 12 stress factors was 7 (8.5%). The number employees with more than 12 stress factors in different categories of loco pilots were 30 (32%) in the goods category, 12 (12%) in the mail/passenger category, and 7 (19%) in the shunter category, and 3 (11%) in the supervisory category and 4 (7%) in the on-board category of section controllers. The prevalence of hypertension in loco pilots was 36.52% (84) and in the section controllers was 53.66% (44). The prevalence of hypertension in the category with more than 12 stress factors was 30.61% (15) in the loco pilots and 28.57% (2) in the section controllers. The prevalence of hypertension in the both the study groups were higher in the older age, with a family history of hypertension, and with a body mass index of more than 25 kg/m 2 . The mean occupational stress and employees with more than 12 stress factors were higher in the loco pilots group. The goods category of loco pilots had highest stress factors. The prevalence of hypertension was high in the category with risk factors such as older age, family history of hypertension and BMI above 25 kg/m 2 .

Flying Qualities Evaluation of a Commuter Aircraft With an Ice Contaminated Tailplane

NASA Technical Reports Server (NTRS)

Ranaudo, Richard J.; Ratvasky, Thomas P.; FossVanZante, Judith

2000-01-01

During the NASA/FAA (Federal Aviation Administration) Tailplane Icing Program, pilot evaluations of aircraft flying qualities were conducted with various ice shapes attached to the horizontal tailplane of the NASA Twin Otter Icing Research Aircraft. Initially, only NASA pilots conducted these evaluations, assessing the differences in longitudinal flight characteristics between the baseline or clean aircraft, and the aircraft configured with an Ice Contaminated Tailplane (ICT). Longitudinal tests included Constant Airspeed Flap Transitions, Constant Airspeed Thrust Transitions, zero-G Pushovers, Repeat Elevator Doublets, and Simulated Approach and Go-Around tasks. Later in the program, guest pilots from government and industry were invited to fly the NASA Twin Otter configured with a single full-span artificial ice shape attached to the leading edge of the horizontal tailplane. This shape represented ice formed due to a 'Failed Boot' condition, and was generated from tests in the Glenn Icing Research Tunnel on a full-scale tailplane model. Guest pilots performed longitudinal handling tests, similar to those conducted by the NASA pilots, to evaluate the ICT condition. In general, all pilots agreed that longitudinal flying qualities were degraded as flaps were lowered, and further degraded at high thrust settings. Repeat elevator doublets demonstrated reduced pitch damping effects due to ICT, which is a characteristic that results in degraded flying qualities. Pilots identified elevator control force reversals (CFR) in zero-G pushovers at a 20 deg flap setting, a characteristic that fails the FAR 25 no CFR certification requirement. However, when the same pilots used the Cooper-Harper rating scale to perform a simulated approach and go-around task at the 20 deg flap setting, they rated the airplane as having Level I and Level II flying qualities respectively. By comparison, the same task conducted at the 30 deg flap setting, resulted in Level II flying qualities for the approach portion, and Level III for the go-around portion.The results of this program indicate that safe and acceptable flying qualities with an ICT condition, can be effectively assessed by task-oriented pilot maneuvers. In addition, other maneuvers such as repeat elevator doublets provide good qualitative and quantitative assessments of pitch damping and elevator effectiveness, which are characteristics that correlate well with pilot task ratings. The results of this testing indicate that the FAR 25 zero-G pushover maneuver, which requires no CFR during its execution, may be an overly conservative pass/fail criteria for aircraft certification.

Simulation and Study of High Workload Operations

DTIC Science & Technology

1974-04-25

way to proceed. Inviting a test pilot to confess he cannot meet a challenge, or a line pilot to admit he is overpaid, is asking for more than verbal...part of the aaalyais looked for differences hstaaea the subjects. Using buskal Msllis one-way analysis of variance tests these ware found to be present...however, recog- nised that the three flights were intentionally designed to be markedly different from one another, and it remains to test the

DOE Office of Scientific and Technical Information (OSTI.GOV)

Franzese, Oscar; Lascurain, Mary Beth; Capps, Gary J

The Federal Motor Carrier Safety Administration (FMCSA) Wireless Roadside Inspection (WRI) Program is researching the feasibility and value of electronically assessing truck and bus driver and vehicle safety at least 25 times more often than is possible using only roadside physical inspections. The WRI program is evaluating the potential benefits to both the motor carrier industry and to government. These potential benefits include reduction in accidents, fatalities and injuries on our highways and keeping safe and legal drivers and vehicles moving on the highways. WRI Pilot tests were conducted to prototype, test and demonstrate the feasibility and benefits of electronicallymore » collecting safety data message sets from in-service commercial vehicles and performing wireless roadside inspections using three different communication methods. This report summarizes the design, conduct and results of the Tennessee CMRS WRI Pilot Test. The purpose of this Pilot test was to demonstrate the implementation of commercial mobile radio services to electronically request and collect safety data message sets from a limited number of commercial vehicles operating in Tennessee. The results of this test have been used in conjunction with the results of the complimentary pilot tests to support an overall assessment of the feasibility and benefits of WRI in enhancing motor carrier safety (reduction in accidents) due to increased compliance (change in motor carrier and driver behavior) caused by conducting frequent safety inspections electronically, at highway speeds, without delay or need to divert into a weigh station« less

Sequential Design of Experiments to Maximize Learning from Carbon Capture Pilot Plant Testing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Soepyan, Frits B.; Morgan, Joshua C.; Omell, Benjamin P.

Pilot plant test campaigns can be expensive and time-consuming. Therefore, it is of interest to maximize the amount of learning and the efficiency of the test campaign given the limited number of experiments that can be conducted. This work investigates the use of sequential design of experiments (SDOE) to overcome these challenges by demonstrating its usefulness for a recent solvent-based CO2 capture plant test campaign. Unlike traditional design of experiments methods, SDOE regularly uses information from ongoing experiments to determine the optimum locations in the design space for subsequent runs within the same experiment. However, there are challenges that needmore » to be addressed, including reducing the high computational burden to efficiently update the model, and the need to incorporate the methodology into a computational tool. We address these challenges by applying SDOE in combination with a software tool, the Framework for Optimization, Quantification of Uncertainty and Surrogates (FOQUS) (Miller et al., 2014a, 2016, 2017). The results of applying SDOE on a pilot plant test campaign for CO2 capture suggests that relative to traditional design of experiments methods, SDOE can more effectively reduce the uncertainty of the model, thus decreasing technical risk. Future work includes integrating SDOE into FOQUS and using SDOE to support additional large-scale pilot plant test campaigns.« less

Innovative Water Management Technology to Reduce Environmental Impacts of Produced Water

DOE Office of Scientific and Technical Information (OSTI.GOV)

Castle, James; Rodgers, John; Alley, Bethany

2013-05-15

Clemson University with Chevron as an industry partner developed and applied treatment technology using constructed wetland systems to decrease targeted constituents in simulated and actual produced waters to achieve reuse criteria and discharge limits. Pilot-scale and demonstration constructed wetland treatment system (CWTS) experiments led to design strategies for treating a variety of constituents of concern (COCs) in produced waters including divalent metals, metalloids, oil and grease, and ammonia. Targeted biogeochemical pathways for treatment of COCs in pilot-scale CWTS experiments included divalent metal sulfide precipitation through dissimilatory sulfate reduction, metal precipitation through oxidation, reduction of selenite to insoluble elemental selenium, aerobicmore » biodegradation of oil, nitrification of ammonia to nitrate, denitrification of nitrate to nitrogen gas, separation of oil using an oilwater separator, and sorption of ammonia to zeolite. Treatment performance results indicated that CWTSs can be designed and built to promote specific environmental and geochemical conditions in order for targeted biogeochemical pathways to operate. The demonstration system successfully achieved consistent removal extents even while inflow concentrations of COCs in the produced water differed by orders of magnitude. Design strategies used in the pilot-scale and demonstration CWTSs to promote specific conditions that can be applied to designing full-scale CWTSs include plant and soil selection, water-depth selection, addition of amendments, and hydraulic retention time (HRT). These strategies allow conditions within a CWTS to be modified to achieve ranges necessary for the preferred biogeochemical treatment pathways. In the case of renovating a produced water containing COCs that require different biogeochemical pathways for treatment, a CWTS can be designed with sequential cells that promote different conditions. For example, the pilot-scale CWTS for post-reverse osmosis produced water was designed to promote oxidizing conditions within the first wetland cell for nitrification of ammonia, and the subsequent three cells were designed to promote reducing conditions for denitrification of nitrate. By incorporating multiple wetland cells in a CWTS, the conditions within each cell can be modified for removal of specific COCs. In addition, a CWTS designed with multiple cells allows for convenient sample collection points so that biogeochemical conditions of individual cells can be monitored and performance evaluated. Removal rate coefficients determined from the pilot-scale CWTS experiments and confirmed by the demonstration system can be used to calculate HRTs required to treat COCs in full-scale CWTSs. The calculated HRTs can then be used to determine the surface area or ?footprint? of a full-size CWTS for a given inflow rate of produced water.« less

Innovative Water Management Technology to Reduce Environment Impacts of Produced Water

DOE Office of Scientific and Technical Information (OSTI.GOV)

Castle, James W.; Rodgers, John H.; Alley, Bethany

2013-08-08

Clemson University with Chevron as an industry partner developed and applied treatment technology using constructed wetland systems to decrease targeted constituents in simulated and actual produced waters to achieve reuse criteria and discharge limits. Pilot-scale and demonstration constructed wetland treatment system (CWTS) experiments led to design strategies for treating a variety of constituents of concern (COCs) in produced waters including divalent metals, metalloids, oil and grease, and ammonia. Targeted biogeochemical pathways for treatment of COCs in pilot-scale CWTS experiments included divalent metal sulfide precipitation through dissimilatory sulfate reduction, metal precipitation through oxidation, reduction of selenite to insoluble elemental selenium, aerobicmore » biodegradation of oil, nitrification of ammonia to nitrate, denitrification of nitrate to nitrogen gas, separation of oil using an oilwater separator, and sorption of ammonia to zeolite. Treatment performance results indicated that CWTSs can be designed and built to promote specific environmental and geochemical conditions in order for targeted biogeochemical pathways to operate. The demonstration system successfully achieved consistent removal extents even while inflow concentrations of COCs in the produced water differed by orders of magnitude. Design strategies used in the pilot-scale and demonstration CWTSs to promote specific conditions that can be applied to designing full-scale CWTSs include plant and soil selection, water-depth selection, addition of amendments, and hydraulic retention time (HRT). These strategies allow conditions within a CWTS to be modified to achieve ranges necessary for the preferred biogeochemical treatment pathways. In the case of renovating a produced water containing COCs that require different biogeochemical pathways for treatment, a CWTS can be designed with sequential cells that promote different conditions. For example, the pilot-scale CWTS for post-reverse osmosis produced water was designed to promote oxidizing conditions within the first wetland cell for nitrification of ammonia, and the subsequent three cells were designed to promote reducing conditions for denitrification of nitrate. By incorporating multiple wetland cells in a CWTS, the conditions within each cell can be modified for removal of specific COCs. In addition, a CWTS designed with multiple cells allows for convenient sample collection points so that biogeochemical conditions of individual cells can be monitored and performance evaluated. Removal rate coefficients determined from the pilot-scale CWTS experiments and confirmed by the demonstration system can be used to calculate HRTs required to treat COCs in full-scale CWTSs. The calculated HRTs can then be used to determine the surface area or footprint of a full-size CWTS for a given inflow rate of produced water.« less

Innovative Water Management Technology to Reduce Environment Impacts of Produced Water

DOE Office of Scientific and Technical Information (OSTI.GOV)

Castle, James; Rodgers, John; Alley, Bethany

2013-05-15

Clemson University with Chevron as an industry partner developed and applied treatment technology using constructed wetland systems to decrease targeted constituents in simulated and actual produced waters to achieve reuse criteria and discharge limits. Pilot-scale and demonstration constructed wetland treatment system (CWTS) experiments led to design strategies for treating a variety of constituents of concern (COCs) in produced waters including divalent metals, metalloids, oil and grease, and ammonia. Targeted biogeochemical pathways for treatment of COCs in pilot-scale CWTS experiments included divalent metal sulfide precipitation through dissimilatory sulfate reduction, metal precipitation through oxidation, reduction of selenite to insoluble elemental selenium, aerobicmore » biodegradation of oil, nitrification of ammonia to nitrate, denitrification of nitrate to nitrogen gas, separation of oil using an oilwater separator, and sorption of ammonia to zeolite. Treatment performance results indicated that CWTSs can be designed and built to promote specific environmental and geochemical conditions in order for targeted biogeochemical pathways to operate. The demonstration system successfully achieved consistent removal extents even while inflow concentrations of COCs in the produced water differed by orders of magnitude. Design strategies used in the pilot-scale and demonstration CWTSs to promote specific conditions that can be applied to designing full-scale CWTSs include plant and soil selection, water-depth selection, addition of amendments, and hydraulic retention time (HRT). These strategies allow conditions within a CWTS to be modified to achieve ranges necessary for the preferred biogeochemical treatment pathways. In the case of renovating a produced water containing COCs that require different biogeochemical pathways for treatment, a CWTS can be designed with sequential cells that promote different conditions. For example, the pilot-scale CWTS for post-reverse osmosis produced water was designed to promote oxidizing conditions within the first wetland cell for nitrification of ammonia, and the subsequent three cells were designed to promote reducing conditions for denitrification of nitrate. By incorporating multiple wetland cells in a CWTS, the conditions within each cell can be modified for removal of specific COCs. In addition, a CWTS designed with multiple cells allows for convenient sample collection points so that biogeochemical conditions of individual cells can be monitored and performance evaluated. Removal rate coefficients determined from the pilot-scale CWTS experiments and confirmed by the demonstration system can be used to calculate HRTs required to treat COCs in full-scale CWTSs. The calculated HRTs can then be used to determine the surface area or footprint of a full-size CWTS for a given inflow rate of produced water.« less

Results of a Pilot-Scale Disinfection Test using Peracetic Acid (PAA) at the Oak Ridge National Laboratory (ORNL) Sewage Treatment Plant (STP)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Taylor, Paul Allen

The purpose of this report is to present the results of a small pilot-scale test using PAA to disinfect a side stream of the effluent from the ORNL STP. These results provide the basis for requesting approval for full-scale use of PAA at the ORNL STP.

Pilot Testing "Okay with Asthma"[TM]: An Online Asthma Intervention for School-Age Children

ERIC Educational Resources Information Center

Wyatt, Tami H.; Hauenstein, Emily J.

2008-01-01

Asthma is the leading cause of missed school days despite advancements in asthma treatment. This may be, in part, due to a lack of understanding about asthma. "Okay With Asthma"[TM], an online story with psychosocial management strategies for school-age children, was pilot tested to measure its effect on asthma knowledge and attitude. The online…

"We the People" Curriculum: Results of Pilot Test. A Report to the Center for Civic Education

ERIC Educational Resources Information Center

Hartry, Ardice; Porter, Kristie

2004-01-01

In the United States, civic educators are debating the need to mandate the inclusion of civic education in high school curriculum. This report describes the result of a pilot test for one curriculum, "We the People: the Citizen and the Constitution." In January 2003, the Center for Civic Education contracted with MPR Associates, Inc. to…

Changing Parent's Mindfulness, Child Management Skills and Relationship Quality with Their Youth: Results from a Randomized Pilot Intervention Trial

ERIC Educational Resources Information Center

Coatsworth, J. Douglas; Duncan, Larissa G.; Greenberg, Mark T.; Nix, Robert L.

2010-01-01

We evaluated the efficacy of a mindful parenting program for changing parents' mindfulness, child management practices, and relationships with their early adolescent youth and tested whether changes in parents' mindfulness mediated changes in other domains. We conducted a pilot randomized trial with 65 families and tested an adapted version of the…

Report on Pilot Test Of Impact and In-Depth Measures. Child and Family Mental Health Project.

ERIC Educational Resources Information Center

Condry, Sandra; Hayes, William A.

This document reports the pilot test of the two components of the Child and Family Mental Health (CFMH) Evaluation Project -- the impact evaluation component and the in-depth evaluation component. (The impact evaluation is designed to determine the effects of the two primary prevention models of service and activities on the CFMH Head Start…

40 CFR Appendix - Tables to Subpart B of Part 88

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 20 2014-07-01 2013-07-01 true Tables to Subpart B of Part 88 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CLEAN-FUEL VEHICLES California Pilot Test Program State opt-in for the California Pilot Test Program. Pt. 88, Subpt. B, Tables Tables to Subpart B of Part 88 Tabl...

View of White Room atop Pad A during Apollo 9 Countdown Demonstration Test

NASA Technical Reports Server (NTRS)

1969-01-01

Interior view of the White Room atop Pad A, Launch Complex 39, Kenndy Space Center, during Apollo 9 Countdown Demonstration Test activity. Standing next to spacecraft hatch is Astronaut James A. McDivitt, commander. Also taking part in the training exercise were Astronauts David R. Scott, command module pilot; and Russell L. Schweickart, lunar module pilot.

Iowa CASAS Pilot Project Reports: An Initial Evaluation of CASAS Effectiveness in Iowa's Adult Basic Education Programs.

ERIC Educational Resources Information Center

Strom, Mary L.

In fall 1992, the Iowa Department of Education began pilot tests of the Comprehensive Adult Student Assessment System (CASAS), an assessment system evaluating reading, math, and problem solving in a life skills context for adult remedial programs. This document provides reports from the nine community colleges that served as test sites, describing…

Validation of an Instrument to Measure High School Students' Attitudes toward Fitness Testing

ERIC Educational Resources Information Center

Mercier, Kevin; Silverman, Stephen

2014-01-01

Purpose: The purpose of this investigation was to develop an instrument that has scores that are valid and reliable for measuring students' attitudes toward fitness testing. Method: The method involved the following steps: (a) an elicitation study, (b) item development, (c) a pilot study, and (d) a validation study. The pilot study included 427…

Building Academic Skills in Context: Testing the Value of Enhanced Math Learning in CTE. Pilot Study

ERIC Educational Resources Information Center

Stone, James R., III; Alfeld, Corinne; Pearson, Donna; Lewis, Morgan V.; Jensen, Susan

2005-01-01

This report describes the conduct and outcomes of an experimental pilot study conducted in Spring 2004 to develop and test a model that aimed to enhance career and technical education (CTE) instruction with the mathematics already embedded in the curricula of six occupational areas. Although present in the CTE curriculum, math is largely implicit…

Analytical methodology for determination of helicopter IFR precision approach requirements. [pilot workload and acceptance level

NASA Technical Reports Server (NTRS)

Phatak, A. V.

1980-01-01

A systematic analytical approach to the determination of helicopter IFR precision approach requirements is formulated. The approach is based upon the hypothesis that pilot acceptance level or opinion rating of a given system is inversely related to the degree of pilot involvement in the control task. A nonlinear simulation of the helicopter approach to landing task incorporating appropriate models for UH-1H aircraft, the environmental disturbances and the human pilot was developed as a tool for evaluating the pilot acceptance hypothesis. The simulated pilot model is generic in nature and includes analytical representation of the human information acquisition, processing, and control strategies. Simulation analyses in the flight director mode indicate that the pilot model used is reasonable. Results of the simulation are used to identify candidate pilot workload metrics and to test the well known performance-work-load relationship. A pilot acceptance analytical methodology is formulated as a basis for further investigation, development and validation.

Cocurrent scrubber evaluation TVA's Colbert Lime--Limestone Wet-Scrubbing Pilot Plant. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robards, R.F.; Moore, N.D.; Kelso, T.M.

1979-01-01

The Tennessee Valley Authority (TVA) is actively engaged in a pilot plant program to develop and/or evaluate wet-scrubbing processes for removing sulfur dioxide (SO/sub 2/) from boiler flue gas. The physical size and general arrangement of flue gas scrubbing systems have a major impact on capital investment and operating cost, as do potential operating and maintenance advantages inherent to some systems. The equipment configuration for a cocurrent scrubber reflects some of these advantages. EPRI funded TVA to perform preliminary screening tests of TVA's 1 MW pilot plant (Colbert Steam Plant) to develop operating data on the cocurrent design for usemore » in designing and operating a 10 MW prototype cocurrent scrubber at TVA's Shawnee Scrubber Test Facility. Results of the Colbert tests showed excellent sulfur dioxide removal efficiencies, generally greater than 85%, low pressure drop, and high particulate removal efficiencies. This report covers these screening tests.« less

Refining and end use study of coal liquids II - linear programming analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lowe, C.; Tam, S.

1995-12-31

A DOE-funded study is underway to determine the optimum refinery processing schemes for producing transportation fuels that will meet CAAA regulations from direct and indirect coal liquids. The study consists of three major parts: pilot plant testing of critical upgrading processes, linear programming analysis of different processing schemes, and engine emission testing of final products. Currently, fractions of a direct coal liquid produced form bituminous coal are being tested in sequence of pilot plant upgrading processes. This work is discussed in a separate paper. The linear programming model, which is the subject of this paper, has been completed for themore » petroleum refinery and is being modified to handle coal liquids based on the pilot plant test results. Preliminary coal liquid evaluation studies indicate that, if a refinery expansion scenario is adopted, then the marginal value of the coal liquid (over the base petroleum crude) is $3-4/bbl.« less

Desktop document delivery using portable document format (PDF) files and the Web.

PubMed Central

Shipman, J P; Gembala, W L; Reeder, J M; Zick, B A; Rainwater, M J

1998-01-01

Desktop access to electronic full-text literature was rated one of the most desirable services in a client survey conducted by the University of Washington Libraries. The University of Washington Health Sciences Libraries (UW HSL) conducted a ten-month pilot test from August 1996 to May 1997 to determine the feasibility of delivering electronic journal articles via the Internet to remote faculty. Articles were scanned into Adobe Acrobat Portable Document Format (PDF) files and delivered to individuals using Multipurpose Internet Mail Extensions (MIME) standard e-mail attachments and the Web. Participants retrieved scanned articles and used the Adobe Acrobat Reader software to view and print files. The pilot test required a special programming effort to automate the client notification and file deletion processes. Test participants were satisfied with the pilot test despite some technical difficulties. Desktop delivery is now offered as a routine delivery method from the UW HSL. PMID:9681165

Desktop document delivery using portable document format (PDF) files and the Web.

PubMed

Shipman, J P; Gembala, W L; Reeder, J M; Zick, B A; Rainwater, M J

1998-07-01

Desktop access to electronic full-text literature was rated one of the most desirable services in a client survey conducted by the University of Washington Libraries. The University of Washington Health Sciences Libraries (UW HSL) conducted a ten-month pilot test from August 1996 to May 1997 to determine the feasibility of delivering electronic journal articles via the Internet to remote faculty. Articles were scanned into Adobe Acrobat Portable Document Format (PDF) files and delivered to individuals using Multipurpose Internet Mail Extensions (MIME) standard e-mail attachments and the Web. Participants retrieved scanned articles and used the Adobe Acrobat Reader software to view and print files. The pilot test required a special programming effort to automate the client notification and file deletion processes. Test participants were satisfied with the pilot test despite some technical difficulties. Desktop delivery is now offered as a routine delivery method from the UW HSL.

VSTOL Systems Research Aircraft (VSRA) Harrier

NASA Technical Reports Server (NTRS)

1994-01-01

NASA's Ames Research Center has developed and is testing a new integrated flight and propulsion control system that will help pilots land aircraft in adverse weather conditions and in small confined ares (such as, on a small ship or flight deck). The system is being tested in the V/STOL (Vertical/Short Takeoff and Landing) Systems research Aircraft (VSRA), which is a modified version of the U.S. Marine Corps's AV-8B Harrier jet fighter, which can take off and land vertically. The new automated flight control system features both head-up and panel-mounted computer displays and also automatically integrates control of the aircraft's thrust and thrust vector control, thereby reducing the pilot's workload and help stabilize the aircraft for landing. Visiting pilots will be encouraged to test the new system and provide formal evaluation flights data and feedback. An actual flight test and the display panel of control system are shown in this video.

ATD Occupant Responses from Three Full-Scale General Aviation Crash Tests

NASA Technical Reports Server (NTRS)

Littell, Justin D.; Annett, Martin S.

2016-01-01

During the summer of 2015, three Cessna 172 General Aviation (GA) aircraft were crash tested at the Landing and Impact Research (LandIR) Facility at NASA Langley Research Center (LaRC). Three different crash scenarios were represented. The first test simulated a flare-to-stall emergency or hard landing onto a rigid surface such as a road or runway. The second test simulated a controlled flight into terrain with a nose down pitch of the aircraft, and the third test simulated a controlled flight into terrain with an attempt to unsuccessfully recover the aircraft immediately prior to impact, resulting in a tail strike condition. An on-board data acquisition system (DAS) captured 64 channels of airframe acceleration, along with accelerations and loads in two onboard Hybrid II 50th percentile Anthropomorphic Test Devices (ATDs) representing the pilot and copilot. Each of the three tests contained different airframe loading conditions and different types of restraints for both the pilot and co-pilot ATDs. The results show large differences in occupant response and restraint performance with varying likelihoods of occupant injury.

Automated Pilot Advisory System

NASA Technical Reports Server (NTRS)

Parks, J. L., Jr.; Haidt, J. G.

1981-01-01

An Automated Pilot Advisory System (APAS) was developed and operationally tested to demonstrate the concept that low cost automated systems can provide air traffic and aviation weather advisory information at high density uncontrolled airports. The system was designed to enhance the see and be seen rule of flight, and pilots who used the system preferred it over the self announcement system presently used at uncontrolled airports.