Virus removal retention challenge tests performed at lab scale and pilot scale during operation of membrane units.

PubMed

Humbert, H; Machinal, C; Labaye, Ivan; Schrotter, J C

2011-01-01

The determination of the virus retention capabilities of UF units during operation is essential for the operators of drinking water treatment facilities in order to guarantee an efficient and stable removal of viruses through time. In previous studies, an effective method (MS2-phage challenge tests) was developed by the Water Research Center of Veolia Environnement for the measurement of the virus retention rates (Log Removal Rate, LRV) of commercially available hollow fiber membranes at lab scale. In the present work, the protocol for monitoring membrane performance was transferred from lab scale to pilot scale. Membrane performances were evaluated during pilot trial and compared to the results obtained at lab scale with fibers taken from the pilot plant modules. PFU culture method was compared to RT-PCR method for the calculation of LRV in both cases. Preliminary tests at lab scale showed that both methods can be used interchangeably. For tests conducted on virgin membrane, a good consistency was observed between lab and pilot scale results with the two analytical methods used. This work intends to show that a reliable determination of the membranes performances based on RT-PCR analytical method can be achieved during the operation of the UF units.

Conducting pilot and feasibility studies.

PubMed

Cope, Diane G

2015-03-01

Planning a well-designed research study can be tedious and laborious work. However, this process is critical and ultimately can produce valid, reliable study findings. Designing a large-scale randomized, controlled trial (RCT)-the gold standard in quantitative research-can be even more challenging. Even the most well-planned study potentially can result in issues with research procedures and design, such as recruitment, retention, or methodology. One strategy that may facilitate sound study design is the completion of a pilot or feasibility study prior to the initiation of a larger-scale trial. This article will discuss pilot and feasibility studies, their advantages and disadvantages, and implications for oncology nursing research. 
.

UV/H2O2 process stability and pilot-scale validation for trace organic chemical removal from wastewater treatment plant effluents.

PubMed

Miklos, David B; Hartl, Rebecca; Michel, Philipp; Linden, Karl G; Drewes, Jörg E; Hübner, Uwe

2018-06-01

This study investigated the removal of 15 trace organic chemicals (TOrCs) occurring at ambient concentrations from municipal wastewater treatment plant effluent by advanced oxidation using UV/H 2 O 2 at pilot-scale. Pseudo first-order rate constants (k obs ) for photolytic as well as combined oxidative and photolytic degradation observed at pilot-scale were validated with results from a bench-scale collimated beam device. No significant difference was determined between pilot- and lab-scale performance. During continuous pilot-scale operation at constant UV fluence of 800 mJ/cm 2 and H 2 O 2 dosage of 10 mg/L, the removal of various TOrCs was investigated. The average observed removal for photo-susceptible (k UV >10 -3  cm 2 /mJ; like diclofenac, iopromide and sulfamethoxazole), moderately photo-susceptible (10 -4

CHLORINE DECAY AND BIOFILM STUDIES IN A PILOT SCALE DRINKING WATER DISTRIBUTION DEAD END PIPE SYSTEM

EPA Science Inventory

Chlorine decay experiments using a pilot-scale water distribution dead end pipe system were conducted to define relationships between chlorine decay and environmental factors. These included flow rate, biomass concentration and biofilm density, and initial chlorine concentrations...

Removal of adenovirus, calicivirus, and bacteriophages by conventional drinking water treatment.

PubMed

Abbaszadegan, Morteza; Monteiro, Patricia; Nwachuku, Nena; Alum, Absar; Ryu, Hodon

2008-02-01

This study was conducted to evaluate the removal of adenovirus, feline calicivirus (FCV), and bacteriophages MS-2, fr, PRD-1, and Phi X-174 during conventional drinking water treatment using ferric chloride as a coagulant. Adenovirus and FCV were removed to a greater extent than PRD-1 and Phi X-174, indicating that these bacteriophages may be appropriate surrogates for both adenovirus and FCV. Of the four bacteriophages studied in the pilot plant, MS-2 was removed to the greatest extent (5.1 log), followed by fr (4.9 log), PRD-1 (3.5 log), and Phi X-174 (1.3 log). The virus removal trend in the pilot-scale testing was similar to the bench-scale testing; however, the bench-scale testing seemed to provide a conservative estimate of the pilot plant performance. In the pilot-scale testing, MS-2 and fr were removed with the greatest efficiency during filtration, whereas PRD-1 and Phi X-174 showed the greatest removal during sedimentation.

A Social-Cognitive Intervention Program for Adolescents with Autism: A Pilot Study

ERIC Educational Resources Information Center

Cheung, Pui Pui Phoebe; Siu, Andrew M. H.; Brown, Ted; Yu, Mong-lin

2018-01-01

This pilot study explored the efficacy of a social-cognitive intervention program for adolescents with Autism Spectrum Disorder (ASD). Seven adolescents with ASD (mean age = 12.57 years) attended a school-based 10-week program. Social Skills Improvement System Rating Scales, Goal Attainment Scaling (GAS), and Theory of Mind Inventory were…

Scaling Down to Scale Up: A Health Economic Analysis of Integrating Point-of-Care Syphilis Testing into Antenatal Care in Zambia during Pilot and National Rollout Implementation

PubMed Central

Ncube, Alexander Tshaka; Sweeney, Sedona; Fleischer, Colette; Mumba, Grace Tembo; Gill, Michelle M.; Strasser, Susan; Peeling, Rosanna W.; Terris-Prestholt, Fern

2015-01-01

Maternal syphilis results in an estimated 500,000 stillbirths and neonatal deaths annually in Sub-Saharan Africa. Despite the existence of national guidelines for antenatal syphilis screening, syphilis testing is often limited by inadequate laboratory and staff services. Recent availability of inexpensive rapid point-of-care syphilis tests (RST) can improve access to antenatal syphilis screening. A 2010 pilot in Zambia explored the feasibility of integrating RST within prevention of mother-to-child-transmission of HIV services. Following successful demonstration, the Zambian Ministry of Health adopted RSTs into national policy in 2011. Cost data from the pilot and 2012 preliminary national rollout were extracted from project records, antenatal registers, clinic staff interviews, and facility observations, with the aim of assessing the cost and quality implications of scaling up a successful pilot into a national rollout. Start-up, capital, and recurrent cost inputs were collected, including costs of extensive supervision and quality monitoring during the pilot. Costs were analysed from a provider’s perspective, incremental to existing antenatal services. Total and unit costs were calculated and a multivariate sensitivity analysis was performed. Our accompanying qualitative study by Ansbro et al. (2015) elucidated quality assurance and supervisory system challenges experienced during rollout, which helped explain key cost drivers. The average unit cost per woman screened during rollout ($11.16) was more than triple the pilot unit cost ($3.19). While quality assurance costs were much lower during rollout, the increased unit costs can be attributed to several factors, including higher RST prices and lower RST coverage during rollout, which reduced economies of scale. Pilot and rollout cost drivers differed due to implementation decisions related to training, supervision, and quality assurance. This study explored the cost of integrating RST into antenatal care in pilot and national rollout settings, and highlighted important differences in costs that may be observed when moving from pilot to scale-up. PMID:25970443

Scaling Down to Scale Up: A Health Economic Analysis of Integrating Point-of-Care Syphilis Testing into Antenatal Care in Zambia during Pilot and National Rollout Implementation.

PubMed

Shelley, Katharine D; Ansbro, Éimhín M; Ncube, Alexander Tshaka; Sweeney, Sedona; Fleischer, Colette; Tembo Mumba, Grace; Gill, Michelle M; Strasser, Susan; Peeling, Rosanna W; Terris-Prestholt, Fern

2015-01-01

Maternal syphilis results in an estimated 500,000 stillbirths and neonatal deaths annually in Sub-Saharan Africa. Despite the existence of national guidelines for antenatal syphilis screening, syphilis testing is often limited by inadequate laboratory and staff services. Recent availability of inexpensive rapid point-of-care syphilis tests (RST) can improve access to antenatal syphilis screening. A 2010 pilot in Zambia explored the feasibility of integrating RST within prevention of mother-to-child-transmission of HIV services. Following successful demonstration, the Zambian Ministry of Health adopted RSTs into national policy in 2011. Cost data from the pilot and 2012 preliminary national rollout were extracted from project records, antenatal registers, clinic staff interviews, and facility observations, with the aim of assessing the cost and quality implications of scaling up a successful pilot into a national rollout. Start-up, capital, and recurrent cost inputs were collected, including costs of extensive supervision and quality monitoring during the pilot. Costs were analysed from a provider's perspective, incremental to existing antenatal services. Total and unit costs were calculated and a multivariate sensitivity analysis was performed. Our accompanying qualitative study by Ansbro et al. (2015) elucidated quality assurance and supervisory system challenges experienced during rollout, which helped explain key cost drivers. The average unit cost per woman screened during rollout ($11.16) was more than triple the pilot unit cost ($3.19). While quality assurance costs were much lower during rollout, the increased unit costs can be attributed to several factors, including higher RST prices and lower RST coverage during rollout, which reduced economies of scale. Pilot and rollout cost drivers differed due to implementation decisions related to training, supervision, and quality assurance. This study explored the cost of integrating RST into antenatal care in pilot and national rollout settings, and highlighted important differences in costs that may be observed when moving from pilot to scale-up.

PILOT-SCALE EVALUATION OF NEW RESIN APPLICATION EQUIPMENT FOR FIBER- REINFORCED PLASTICS

EPA Science Inventory

The article gives results of a pilot-scale evaluation of new resin application equipment for fiber- reinforced plastics. The study, an evaluation and comparison of styrene emissions, utilized Magnum's FIT(TM) nozzle with conventional spray guns and flow coaters (operated at both ...

Assessment of sleepiness, fatigue, and depression among Gulf Cooperation Council commercial airline pilots.

PubMed

Aljurf, Tareq M; Olaish, Awad H; BaHammam, Ahmed S

2018-05-01

No studies have assessed the prevalence of fatigue, depression, sleepiness, and the risk of obstructive sleep apnea (OSA) among commercial airlines pilots in the Gulf Cooperation Council (GCC). This was a quantitative cross-sectional study conducted among pilots who were on active duty and had flown during the past 6 months for one of three commercial airline companies. We included participants with age between 20 and 65 years. Data were collected using a predesigned electronic questionnaire composed of questions related to demographic information in addition to the Fatigue Severity Scale (FSS), the Berlin Questionnaire, the Epworth Sleepiness Scale (ESS), and the Hospital Anxiety and Depression Scale (HADS). The study included 328 pilots with a mean age ± standard deviation of 41.4 ± 9.7 years. Overall, 224 (68.3%) pilots had an FSS score ≥ 36 indicating severe fatigue and 221 (67.4%) reported making mistakes in the cockpit because of fatigue. One hundred and twelve (34.1%) pilots had an ESS score ≥ 10 indicating excessive daytime sleepiness and 148 (45.1%) reported falling asleep at the controls at least once without previously agreeing with their colleagues. One hundred and thirteen (34.5%) pilots had an abnormal HADS depression score (≥ 8), and 96 (29.3%) pilots were at high risk for OSA requiring further assessment. Fatigue, sleepiness, risk of OSA, and depression are prevalent among GCC commercial airline pilots. Regular assessment by aviation authorities is needed to detect and treat these medical problems.

PILOT-SCALE STUDIES ON THE EFFECT OF BROMINE ADDITION ON THE EMISSIONS OF CHLORINATED ORGANIC COMBUSTION BY-PRODUCTS

EPA Science Inventory

The addition of brominated organic compounds to the feed of a pilot-scale incinerator burning chlorinated waste has been found previously, under some circumstances, to enhance emissions of volatile and semivolatile organic chlorinated products of incomplete combustion (PiCs) incl...

Sharing the Data along with the Responsibility: Examining an Analytic Scale-Based Model for Assessing School Climate.

ERIC Educational Resources Information Center

Shindler, John; Taylor, Clint; Cadenas, Herminia; Jones, Albert

This study was a pilot effort to examine the efficacy of an analytic trait scale school climate assessment instrument and democratic change system in two urban high schools. Pilot study results indicate that the instrument shows promising soundness in that it exhibited high levels of validity and reliability. In addition, the analytic trait format…

INACTIVATION OF CRYPTOSPORIDIUM OOCYSTS IN A PILOT-SCALE OZONE BUBBLE-DIFFUSER CONTACTOR - II: MODEL VALIDATION AND APPLICATION

EPA Science Inventory

The ADR model developed in Part I of this study was successfully validated with experimenta data obtained for the inactivation of C. parvum and C. muris oocysts with a pilot-scale ozone-bubble diffuser contactor operated with treated Ohio River water. Kinetic parameters, required...

A PILOT-SCALE STUDY OF THE PRECURSORS LEADING TO THE FORMATION OF MIXED BROMO-CHLORO DIOXINS AND FURANS

EPA Science Inventory

The paper gives results of experiments in a pilot-scale rotary kiln incinerator simulator where a mixture of chlorinated and brominated surrogate waste was burned in the presence of injected fly-ash from a coal-fired utility boiler. Measurements were made of semivolatile products...

A PILOT-SCALE STUDY ON THE COMBUSTION OF WASTE ...

EPA Pesticide Factsheets

Symposium Paper Post-consumer carpet is a potential substitute fuel for high temperature thermal processes such as cement kilns and boilers.This paper reports on results examining emissions of PCDDs/Fs from a series of pilot-scale experiments performed on the EPA's rotary kiln incinerator simulator facility in Research triangle Park, NC.

RECYCLING A NONIONIC AQUEOUS-BASED METAL-CLEANING SOLUTION WITH A CERAMIC MEMBRANE: PILOT SCALE EVALUATION

EPA Science Inventory

The effectiveness of a zirconium dioxide (ZrO2) membrane filter was evaluated for recycling a nonionic aqueous metal cleaning bath under real-world conditions. The pilot-scale study consisted of four 7- to 16-day filtration runs, each processed a portion of the cleaning bath duri...

Pilot-scale demonstration of SPORL for bioconversion of lodgepole pine to bioethanol and lignosulfonate

Treesearch

Haifeng Zhou; Junyong Zhu; Roland Gleisner; Xueqing Qiu; Eric Horn; Jose Negron

2016-01-01

The process sulfite pretreatment to overcome recalcitrance of lignocelluloses (SPORL) has been the focus of this study. Pilot-scale (50 kg) pretreatment of wood chips of lodgepole pine (Pinus contorta Douglas ex Loudon) killed by mountain pine beetle (Dendroctonus ponderosae Hopkins) were conducted at 165°C...

[Yield of starch extraction from plantain (Musa paradisiaca). Pilot plant study].

PubMed

Flores-Gorosquera, Emigdia; García-Suárez, Francisco J; Flores-Huicochea, Emmanuel; Núñez-Santiago, María C; González-Soto, Rosalia A; Bello-Pérez, Luis A

2004-01-01

In México, the banana (Musa paradisiaca) is cooked (boiling or deep frying) before being eaten, but the consumption is not very popular and a big quantity of the product is lost after harvesting. The unripe plantain has a high level of starch and due to this the use of banana can be diversified as raw material for starch isolation. The objective of this work was to study the starch yield at pilot plant scale. Experiments at laboratory scale were carried out using the pulp with citric acid to 0,3 % (antioxidant), in order to evaluate the different unitary operations of the process. The starch yield, based on starch presence in the pulp that can be isolated, were between 76 and 86 %, and the values at pilot plant scale were between 63 and 71 %, in different lots of banana fruit. Starch yield values were similar among the diverse lots, showing that the process is reproducible. The lower values of starch recovery at pilot plant scale are due to the loss during sieving operations; however, the amount of starch recovery is good.

New mechanistically based model for predicting reduction of biosolids waste by ozonation of return activated sludge.

PubMed

Isazadeh, Siavash; Feng, Min; Urbina Rivas, Luis Enrique; Frigon, Dominic

2014-04-15

Two pilot-scale activated sludge reactors were operated for 98 days to provide the necessary data to develop and validate a new mathematical model predicting the reduction of biosolids production by ozonation of the return activated sludge (RAS). Three ozone doses were tested during the study. In addition to the pilot-scale study, laboratory-scale experiments were conducted with mixed liquor suspended solids and with pure cultures to parameterize the biomass inactivation process during exposure to ozone. The experiments revealed that biomass inactivation occurred even at the lowest doses, but that it was not associated with extensive COD solubilization. For validation, the model was used to simulate the temporal dynamics of the pilot-scale operational data. Increasing the description accuracy of the inactivation process improved the precision of the model in predicting the operational data. Copyright © 2014 Elsevier B.V. All rights reserved.

[Development of an activity of daily living scale for patients with COPD: the Activity of Daily Living Dyspnea scale].

PubMed

Yoza, Yoshiyasu; Ariyoshi, Koya; Honda, Sumihisa; Taniguchi, Hiroyuki; Senjyu, Hideaki

2009-10-01

Patients with COPD often experience restriction in their activities of daily living (ADL) due to dyspnea. This type of restriction is unique to patients with COPD and cannot be adequately evaluated by the generic ADL scales. This study developed an ADL scale (the Activity of Daily Living Dyspnea scale [ADL-D scale]) for patients with COPD and investigated its validity and internal consistency. Patients with stable COPD were recruited and completed a pilot 26-item questionnaire. Patients also performed the Incremental Shuttle Walk Test (ISWT), and completed the St George's Respiratory Questionnaire (SGRQ), and Medical Research Council (MRC) dyspnea grade. There were 83 male participants who completed the pilot questionnaire. Following the pilot, 8 items that were not undertaken by the majority of subjects, and 3 items judged to be of low clinical importance by physical therapists were removed from the pilot questionnaire. The final ADL-D scale contained 15 items. Scores obtained with the ADL-D scale were significantly correlated with the MRC dyspnea grades, distance walked on the ISWT and SGRQ scores. The ADL-D scores were significantly different across the five grades of the MRC dyspnea grade. The ADL-D scale showed high consistency (Chronbach's alpha coefficient of 0.96). The ADL-D scale is a useful scale for assessing impairments in ADL in Japanese male patients with COPD.

Evaluation of a UV/Ozone Treatment Process for Removal of MTBE in Groundwater Supplies in New Mexico

EPA Science Inventory

EPA’s Office of Research and Development is funding pilot-scale studies on MTBE contaminated groundwater using UV/ozone treatment technology (254 nm UV, 5.8 mg/L ozone). The pilot-scale treatment system consists of a GW well pump, a feed tank, a pretreatment system (water soften...

Evaluation of a UV/Ozone Treatment Process for Removal of MTBE in Groundwater Supplies in New Mexico

EPA Science Inventory

EPA’s Office of Research and Development is funding pilot-scale studies on MTBE contaminated groundwater using UV/ozone treatment technology (254 nm UV, 5.8 mg/L ozone). The pilot-scale treatment system consists of a GW well pump, a feed tank, a pretreatment system (water softene...

Comparison of lab, pilot, and industrial scale low consistency mechanical refining for improvements in enzymatic digestibility of pretreated hardwood.

PubMed

Jones, Brandon W; Venditti, Richard; Park, Sunkyu; Jameel, Hasan

2014-09-01

Mechanical refining has been shown to improve biomass enzymatic digestibility. In this study industrial high-yield sodium carbonate hardwood pulp was subjected to lab, pilot and industrial refining to determine if the mechanical refining improves the enzymatic hydrolysis sugar conversion efficiency differently at different refining scales. Lab, pilot and industrial refining increased the biomass digestibility for lignocellulosic biomass relative to the unrefined material. The sugar conversion was increased from 36% to 65% at 5 FPU/g of biomass with industrial refining at 67.0 kWh/t, which was more energy efficient than lab and pilot scale refining. There is a maximum in the sugar conversion with respect to the amount of refining energy. Water retention value is a good predictor of improvements in sugar conversion for a given fiber source and composition. Improvements in biomass digestibility with refining due to lab, pilot plant and industrial refining were similar with respect to water retention value. Published by Elsevier Ltd.

Treatment of duck house wastewater by a pilot-scale sequencing batch reactor system for sustainable duck production.

PubMed

Su, Jung-Jeng; Huang, Jeng-Fang; Wang, Yi-Lei; Hong, Yu-Ya

2018-06-15

The objective of this study is trying to solve water pollution problems related to duck house wastewater by developing a novel duck house wastewater treatment technology. A pilot-scale sequencing batch reactor (SBR) system using different hydraulic retention times (HRTs) for treating duck house wastewater was developed and applied in this study. Experimental results showed that removal efficiency of chemical oxygen demand in untreated duck house wastewater was 98.4, 98.4, 87.8, and 72.5% for the different HRTs of 5, 3, 1, and 0.5 d, respectively. In addition, removal efficiency of biochemical oxygen demand in untreated duck house wastewater was 99.6, 99.3, 90.4, and 58.0%, respectively. The pilot-scale SBR system was effective and deemed capable to be applied to treat duck house wastewater. It is feasible to apply an automatic SBR system on site based on the previous case study of the farm-scale automatic SBR systems for piggery wastewater treatment.

Designing for Scale: Reflections on Rolling Out Reading Improvement in Kenya and Liberia.

PubMed

Gove, Amber; Korda Poole, Medina; Piper, Benjamin

2017-03-01

Since 2008, the Ministries of Education in Liberia and Kenya have undertaken transitions from small-scale pilot programs to improve reading outcomes among primary learners to the large-scale implementation of reading interventions. The effects of the pilots on learning outcomes were significant, but questions remained regarding whether such large gains could be sustained at scale. In this article, the authors dissect the Liberian and Kenyan experiences with implementing large-scale reading programs, documenting the critical components and conditions of the program designs that affected the likelihood of successfully transitioning from pilot to scale. They also review the design, deployment, and effectiveness of each pilot program and the scale, design, duration, enabling conditions, and initial effectiveness results of the scaled programs in each country. The implications of these results for the design of both pilot and large-scale reading programs are discussed in light of the experiences of both the Liberian and Kenyan programs. © 2017 Wiley Periodicals, Inc.

EMAP WESTERN UNITED STATES LANDSCAPE CHARACTERIZATION SOUTHERN ROCKIES PILOT STUDY AREA DATA AND PRODUCT BROWSER

EPA Science Inventory

The United States Environmental Protection Agency's Environmental Monitoring and Assessment Program (EMAP) is conducting a pilot study in the western United States. This study will advance the science of ecological monitoring and demonstrate techniques for regional-scale assessme...

EMAP WESTERN UNITED STATES LANDSCAPE CHARACTERIZATION NORTHWEST OREGON PILOT STUDY AREA DATA AND PRODUCT BROWSER

EPA Science Inventory

The United States Environmental Protection Agency's Environmental Monitoring and Assessment Program (EMAP) is conducting a pilot study in the western United States. This study will advance the science of ecological monitoring and demonstrate techniques for regional-scale assessme...

Transformation of Bisphenol A in Water Distribution Systems, A Pilot-scale Study

EPA Science Inventory

Halogenations of bisphenol A (BPA) in a pilot-scale water distribution system (WDS) of cement-lined ductile cast iron pipe were investigated under the condition: pH 7.3±0.3, water flow velocity of 1.0 m/s, and 25 °C ± 1 °C in water temperature. The testing water was chlorinated f...

A pilot-scale steam autoclave system for treating municipal solid waste for recovery of renewable organic content: Operational results and energy usage

USDA-ARS?s Scientific Manuscript database

A pilot-scale (1800'kg per batch capacity) autoclave used in this study reduces municipal solid waste to a debris contaminated pulp product that is efficiently separated into its renewable organic content and non-renewable organic content fractions using a rotary trommel screen. The renewable organi...

Consumer Perceptions About Pilot Training: An Emotional Response

NASA Astrophysics Data System (ADS)

Rosser, Timothy G.

Civilian pilot training has followed a traditional path for several decades. With a potential pilot shortage approaching, ICAO proposed a new paradigm in pilot training methodology called the Multi-Crew Pilot License. This new methodology puts a pilot in the cockpit of an airliner with significantly less flight time experience than the traditional methodology. The purpose of this study was to determine to what extent gender, country of origin and pilot training methodology effect an aviation consumer's willingness to fly. Additionally, this study attempted to determine what emotions mediate a consumer's decision. This study surveyed participants from India and the United States to measure their willingness to fly using the Willingness to Fly Scale shown to be valid and reliable by Rice et al. (2015). The scale uses a five point Likert-type scale. In order to determine the mediating emotions, Ekman and Friesen's (1979) universal emotions, which are happiness, surprise, fear, disgust, anger, and sadness were used. Data were analyzed using SPSS. Descriptive statistics are provided for respondent's age and willingness to fly values. An ANOVA was conducted to test the first four hypotheses and Hayes (2004, 2008) bootstrapping process was used for the mediation analysis. Results indicated a significant main effect for training, F(1,972) = 227.76, p . .001, etap 2 = 0.190, country of origin, F(1, 972) = 28.86, p < .001, .p 2 = 0.029, and a two-way interaction was indicated between training and country of origin, F(7, 972) = 46.71, p < .001, etap 2 = 0.252. Mediation analysis indicated the emotions anger, fear, happiness, and surprise mediated the relationship between training and country of origin, and training. The findings of this study are important to designers of MPL training programs and airline marketers.

Scaling-up vaccine production: implementation aspects of a biomass growth observer and controller.

PubMed

Soons, Zita I T A; van den IJssel, Jan; van der Pol, Leo A; van Straten, Gerrit; van Boxtel, Anton J B

2009-04-01

This study considers two aspects of the implementation of a biomass growth observer and specific growth rate controller in scale-up from small- to pilot-scale bioreactors towards a feasible bulk production process for whole-cell vaccine against whooping cough. The first is the calculation of the oxygen uptake rate, the starting point for online monitoring and control of biomass growth, taking into account the dynamics in the gas-phase. Mixing effects and delays are caused by amongst others the headspace and tubing to the analyzer. These gas phase dynamics are modelled using knowledge of the system in order to reconstruct oxygen consumption. The second aspect is to evaluate performance of the monitoring and control system with the required modifications of the oxygen consumption calculation on pilot-scale. In pilot-scale fed-batch cultivation good monitoring and control performance is obtained enabling a doubled concentration of bulk vaccine compared to standard batch production.

Performance of a system with full- and pilot-scale sludge drying reed bed units treating septic tank sludge in Brazil.

PubMed

Calderón-Vallejo, Luisa Fernanda; Andrade, Cynthia Franco; Manjate, Elias Sete; Madera-Parra, Carlos Arturo; von Sperling, Marcos

2015-01-01

This study investigated the performance of sludge drying reed beds (SDRB) at full- and pilot-scale treating sludge from septic tanks in the city of Belo Horizonte, Brazil. The treatment units, planted with Cynodon spp., were based on an adaptation of the first-stage of the French vertical-flow constructed wetland, originally developed for treating sewage. Two different operational phases were investigated; in the first one, the full-scale unit was used together with six pilot-scale columns in order to test different feeding strategies. For the second phase, only the full-scale unit was used, including a recirculation of the filtered effluent (percolate) to one of the units of the French vertical wetland. Sludge application was done once a week emptying a full truck, during 25 weeks. The sludge was predominantly diluted, leading to low solids loading rates (median values of 18 kgTS m(-2) year(-1)). Chemical oxygen demand removal efficiency in the full-scale unit was reasonable (median of 71%), but the total solids removal was only moderate (median of 44%) in the full-scale unit without recirculation. Recirculation did not bring substantial improvements in the overall performance. The other loading conditions implemented in the pilot columns also did not show statistically different performances.

Treatment of the Cerro Prieto I brines for use in reinjection. 2. Results of the pilot plant tests

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hurtado J, R.; Mercado G, S.; Rocha C, E.

Silica removal experiments have been carried out both in the laboratory and in pilot scale tests. The results obtained to date are presented, with special emphasis on the pilot tests with or without the use of flocculants. Previous studies on brine treatment are described briefly.

Neural Network Modeling of UH-60A Pilot Vibration

NASA Technical Reports Server (NTRS)

Kottapalli, Sesi

2003-01-01

Full-scale flight-test pilot floor vibration is modeled using neural networks and full-scale wind tunnel test data for low speed level flight conditions. Neural network connections between the wind tunnel test data and the tlxee flight test pilot vibration components (vertical, lateral, and longitudinal) are studied. Two full-scale UH-60A Black Hawk databases are used. The first database is the NASMArmy UH-60A Airloads Program flight test database. The second database is the UH-60A rotor-only wind tunnel database that was acquired in the NASA Ames SO- by 120- Foot Wind Tunnel with the Large Rotor Test Apparatus (LRTA). Using neural networks, the flight-test pilot vibration is modeled using the wind tunnel rotating system hub accelerations, and separately, using the hub loads. The results show that the wind tunnel rotating system hub accelerations and the operating parameters can represent the flight test pilot vibration. The six components of the wind tunnel N/rev balance-system hub loads and the operating parameters can also represent the flight test pilot vibration. The present neural network connections can significandy increase the value of wind tunnel testing.

Maintenance Decision Support System: Pilot Study and Cost-Benefit Analysis (Phase 2.5)

DOT National Transportation Integrated Search

2014-07-01

This project focused on several tasks: development of in-vehicle hardware that permits implementation of an MDSS, development of software to collect and process road and weather data, a cost-benefit study, and pilot-scale implementation. Two Automati...

Maintenance Decision Support System : Pilot Study and Cost-Benefit Analysis (Phase 2)

DOT National Transportation Integrated Search

2014-07-01

This project focused on several tasks: development of in-vehicle hardware that permits implementation of an MDSS, development of software to collect and process road and weather data, a cost-benefit study, and pilot-scale implementation. Two Automati...

Pilot-scale biopesticide production by Bacillus thuringiensis subsp. kurstaki using starch industry wastewater as raw material.

PubMed

Ndao, Adama; Sellamuthu, Balasubramanian; Gnepe, Jean R; Tyagi, Rajeshwar D; Valero, Jose R

2017-09-02

Pilot-scale Bacillus thuringiensis based biopesticide production (2000 L bioreactor) was conducted using starch industry wastewater (SIW) as a raw material using optimized operational parameters obtained in 15 L and 150 L fermenters. In pilot scale fermentation process the oxygen transfer rate is a major limiting factor for high product yield. Thus, the volumetric mass transfer coefficient (K L a) remains a tool to determine the oxygen transfer capacity [oxygen utilization rate (OUR) and oxygen transfer rate (OTR)] to obtain better bacterial growth rate and entomotoxicity in new bioreactor process optimization and scale-up. This study results demonstrated that the oxygen transfer rate in 2000 L bioreactor was better than 15 L and 150 L fermenters. The better oxygen transfer in 2000 L bioreactor augmented the bacterial growth [total cell (TC) and viable spore count (SC)] and delta-endotoxin yield. Prepared a stable biopesticide formulation for field use and its entomotoxicity was also evaluated. This study result corroborates the feasibility of industrial scale operation of biopesticide production using starch industry wastewater as raw material.

SUPERFUND TREATABILITY CLEARINGHOUSE: FINAL REPORT: SOIL TREATMENT PILOT STUDY BRIO/DOP SITE

EPA Science Inventory

Bench and pilot-scale studies were conducted to demonstrate the feasibility of using solid-phase biodegradation for destroying portions of organic constituents present in the soil. The predominant constituents at the BRIO DOP site located in Texas were volatile compounds such...

ON-SITE ENGINEERING REPORT OF THE SLURRY-PHASE BIOLOGICAL REACTOR FOR PILOT-SCALE TESTING ON CONTAMINATED SOIL

EPA Science Inventory

The performance of pilot-scale bioslurry treatment on creosote-contaminated soil was evaluated. Five reactors containing 66 L of slurry (30% soil by weight), were operated in parallel. The soil was a sandy soil with minor gravel content. The pilot-scale phase utilized an inoculum...

Pilot-scale production of fuel ethanol from concentrated food waste hydrolysates using Saccharomyces cerevisiae H058.

PubMed

Yan, Shoubao; Chen, Xiangsong; Wu, Jingyong; Wang, Pingchao

2013-07-01

The aim of this study was to develop a bioprocess to produce ethanol from food waste at laboratory, semipilot and pilot scales. Laboratory tests demonstrated that ethanol fermentation with reducing sugar concentration of 200 g/L, inoculum size of 2 % (Initial cell number was 2 × 10⁶ CFU/mL) and addition of YEP (3 g/L of yeast extract and 5 g/L of peptone) was the best choice. The maximum ethanol concentration in laboratory scale (93.86 ± 1.15 g/L) was in satisfactory with semipilot scale (93.79 ± 1.11 g/L), but lower than that (96.46 ± 1.12 g/L) of pilot-scale. Similar ethanol yield and volumetric ethanol productivity of 0.47 ± 0.02 g/g, 1.56 ± 0.03 g/L/h and 0.47 ± 0.03 g/g, 1.56 ± 0.03 g/L/h after 60 h of fermentation in laboratory and semipilot fermentors, respectively, however, both were lower than that (0.48 ± 0.02 g/g, 1.79 ± 0.03 g/L/h) of pilot reactor. In addition, simple models were developed to predict the fermentation kinetics during the scale-up process and they were successfully applied to simulate experimental results.

Removal of Multiple Contaminants: Biological Treatment

EPA Science Inventory

This presentation contains (1) background material on nitrate, perchlorate and ammonia contamination in the continental US; (2) scientific background on biological drinking water treatment; (3) results of bench-scale anaerobic and aerobic treatment studies; (4) results of pilot-s...

RESEARCH IN FILTRATION FOR CRYPTOSPORIDIUM REMOVAL

EPA Science Inventory

The USEPA has conducted pilot plant studies for the removal of Cryptosporidium oocysts from drinking water. Fourteen pilot-scale tests were performed to assess the ability of conventional treatment to control Cryptosporidium oocysts and three surrogates; turbidity, total particle...

Flow characteristics of a pilot-scale high temperature, short time pasteurizer.

PubMed

Tomasula, P M; Kozempel, M F

2004-09-01

In this study, we present a method for determining the fastest moving particle (FMP) and residence time distribution (RTD) in a pilot-scale high temperature, short time (HTST) pasteurizer to ensure that laboratory or pilot-scale HTST apparatus meets the Pasteurized Milk Ordinance standards for pasteurization of milk and can be used for obtaining thermal inactivation data. The overall dimensions of the plate in the pasteurizer were 75 x 115 mm, with a thickness of 0.5 mm and effective diameter of 3.0 mm. The pasteurizer was equipped with nominal 21.5- and 52.2-s hold tubes, and flow capacity was variable from 0 to 20 L/h. Tracer studies were used to determine FMP times and RTD data to establish flow characteristics. Using brine milk as tracer, the FMP time for the short holding section was 18.6 s and for the long holding section was 36 s at 72 degrees C, compared with the nominal times of 21.5 and 52.2 s, respectively. The RTD study indicates that the short hold section was 45% back mixed and 55% plug flow for whole milk at 72 degrees C. The long hold section was 91% plug and 9% back mixed for whole milk at 72 degrees C. This study demonstrates that continuous laboratory and pilot-scale pasteurizers may be used to study inactivation of microorganisms only if the flow conditions in the holding tube are established for comparison with commercial HTST systems.

Feasibility study for thermal treatment of solid tire wastes in Bangladesh by using pyrolysis technology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Islam, M.R., E-mail: mrislam1985@yahoo.com; Joardder, M.U.H.; Hasan, S.M.

2011-09-15

In this study on the basis of lab data and available resources in Bangladesh, feasibility study has been carried out for pyrolysis process converting solid tire wastes into pyrolysis oils, solid char and gases. The process considered for detailed analysis was fixed-bed fire-tube heating pyrolysis reactor system. The comparative techno-economic assessment was carried out in US$ for three different sizes plants: medium commercial scale (144 tons/day), small commercial scale (36 tons/day), pilot scale (3.6 tons/day). The assessment showed that medium commercial scale plant was economically feasible, with the lowest unit production cost than small commercial and pilot scale plants formore » the production of crude pyrolysis oil that could be used as boiler fuel oil and for the production of upgraded liquid-products.« less

Using sulfite chemistry for robust bioconversion of Douglas-fir forest residue to bioethanol at high titer and lignosulfonate: A pilot-scale evaluation

Treesearch

J.Y. Zhu; M. Subhosh Chandra; Feng Gu; Roland Gleisner; J.Y. Zhu; John Sessions; Gevan Marrs; Johnway Gao; Dwight Anderson

2015-01-01

This study demonstrated at the pilot-scale (50 kg) use of Douglas-fir forest harvest residue, an underutilized forest biomass, for the production of high titer and high yield bioethanol using sulfite chemistry without solid–liquor separation and detoxification. Sulfite Pretreatment to Overcome the Recalcitrance of Lignocelluloses (SPORL) was directly applied to the...

Process engineering and scale-up of autotrophic Clostridium strain P11 syngas fermentation

NASA Astrophysics Data System (ADS)

Kundiyana, Dimple Kumar Aiyanna

Scope and Method of Study. Biomass gasification followed by fermentation of syngas to ethanol is a potential process to produce bioenergy. The process is currently being researched under laboratory- and pilot-scale in an effort to optimize the process conditions and make the process feasible for commercial production of ethanol and other biofuels such as butanol and propanol. The broad research objectives for the research were to improve ethanol yields during syngas fermentation and to design a economical fermentation process. The research included four statistically designed experimental studies in serum bottles, bench-scale and pilot-scale fermentors to screen alternate fermentation media components, to determine the effect of process parameters such as pH, temperature and buffer on syngas fermentation, to determine the effect of key limiting nutrients of the acetyl-CoA pathway in a continuous series reactor design, and to scale-up the syngas fermentation in a 100-L pilot scale fermentor. Findings and Conclusions. The first experimental study identified cotton seed extract (CSE) as a feasible medium for Clostridium strain P11 fermentation. The study showed that CSE at 0.5 g L-1 can potentially replace all the standard Clostridium strain P11 fermentation media components while using a media buffer did not significantly improve the ethanol production when used in fermentation with CSE. Scale-up of the CSE fermentation in 2-L and 5-L stirred tank fermentors showed 25% increase in ethanol yield. The second experimental study showed that syngas fermentation at 32°C without buffer was associated with higher ethanol concentration and reduced lag time in switching to solventogenesis. Conducting fermentation at 40°C or by lowering incubation pH to 5.0 resulted in reduced cell growth and no production of ethanol or acetic acid. The third experiment studied the effect of three limiting nutrients, calcium pantothenate, vitamin B12 and CoCl2 on syngas fermentation. Results indicated that it is possible to modulate the product formation by limiting key nutrients of acetyl-CoA pathway and using a continuous fermentation in two-stage fermentor design to improve ethanol yields. The last experimental study was conducted to commission a pilot scale fermentor, and subsequently scale-up the Clostridium strain P11 fermentation from a bench-scale to a pilot scale 100-L fermentor. Results indicated a six-fold improvement in ethanol concentration (25.3 g L-1 at the end of 59 d) compared to previous Clostridium strain P11 and Clostridium carboxidivorans fermentations plus the formation of other compounds such as isopropyl alcohol, acetic acid and butanol, which are of commercial importance.

Optimization of the inter-tablet coating uniformity for an active coating process at lab and pilot scale.

PubMed

Just, Sarah; Toschkoff, Gregor; Funke, Adrian; Djuric, Dejan; Scharrer, Georg; Khinast, Johannes; Knop, Klaus; Kleinebudde, Peter

2013-11-30

The objective of this study was to enhance the inter-tablet coating uniformity in an active coating process at lab and pilot scale by statistical design of experiments. The API candesartan cilexetil was applied onto gastrointestinal therapeutic systems containing the API nifedipine to obtain fixed dose combinations of these two drugs with different release profiles. At lab scale, the parameters pan load, pan speed, spray rate and number of spray nozzles were examined. At pilot scale, the parameters pan load, pan speed, spray rate, spray time, and spray pressure were investigated. A low spray rate and a high pan speed improved the coating uniformity at both scales. The number of spray nozzles was identified as the most influential variable at lab scale. With four spray nozzles, the highest CV value was equal to 6.4%, compared to 13.4% obtained with two spray nozzles. The lowest CV of 4.5% obtained with two spray nozzles was further reduced to 2.3% when using four spray nozzles. At pilot scale, CV values between 2.7% and 11.1% were achieved. Since the test of uniformity of dosage units accepts CV values of up to 6.25%, this active coating process is well suited to comply with the pharmacopoeial requirements. Copyright © 2013 Elsevier B.V. All rights reserved.

A tutorial on pilot studies: the what, why and how

PubMed Central

2010-01-01

Pilot studies for phase III trials - which are comparative randomized trials designed to provide preliminary evidence on the clinical efficacy of a drug or intervention - are routinely performed in many clinical areas. Also commonly know as "feasibility" or "vanguard" studies, they are designed to assess the safety of treatment or interventions; to assess recruitment potential; to assess the feasibility of international collaboration or coordination for multicentre trials; to increase clinical experience with the study medication or intervention for the phase III trials. They are the best way to assess feasibility of a large, expensive full-scale study, and in fact are an almost essential pre-requisite. Conducting a pilot prior to the main study can enhance the likelihood of success of the main study and potentially help to avoid doomed main studies. The objective of this paper is to provide a detailed examination of the key aspects of pilot studies for phase III trials including: 1) the general reasons for conducting a pilot study; 2) the relationships between pilot studies, proof-of-concept studies, and adaptive designs; 3) the challenges of and misconceptions about pilot studies; 4) the criteria for evaluating the success of a pilot study; 5) frequently asked questions about pilot studies; 7) some ethical aspects related to pilot studies; and 8) some suggestions on how to report the results of pilot investigations using the CONSORT format. PMID:20053272

Measuring the Immeasurable: A Pilot Study of Museum Effectiveness.

ERIC Educational Resources Information Center

Borun, Minda

The report describes a one-year pilot study of museum effectiveness conducted at the Franklin Institute Science Museum and Planetarium in Philadelphia. The study was intended to develop models for testing visitor response, provide useable information to museum staff, and test the feasibility of a large-scale investigation of science museums.…

CTEPP OVERVIEW: A PILOT STUDY OF CHILDREN'S TOTAL EXPOSURE TO PERSISTENT PESTICIDES AND OTHER PERSISTENT ORGANIC POLLUTANTS

EPA Science Inventory

The research study, "Children's Total Exposure to Persistent Pesticides and Other Persistent Organic Pollutants," (CTEPP) is a pilot-scale project involving about 260 children in their everyday surroundings. The objectives of CTEPP are twofold: (1) To measure the agg...

CSO DISINFECTION PILOT STUDY: SPRING CREEK CSO STORAGE FACILITY UPGRADE

EPA Science Inventory

This research summary presents the results of a pilot-scale disinfection study performed for the New York City Department of Environmental Protection and the U.S. Environmental Protection Agency (US EPA) under a contract to Camp Dresser & McKee of Woodbury, New York. The main ob...

Comparison of batch sorption tests, pilot studies, and modeling for estimating GAC bed life.

PubMed

Scharf, Roger G; Johnston, Robert W; Semmens, Michael J; Hozalski, Raymond M

2010-02-01

Saint Paul Regional Water Services (SPRWS) in Saint Paul, MN experiences annual taste and odor episodes during the warm summer months. These episodes are attributed primarily to geosmin that is produced by cyanobacteria growing in the chain of lakes used to convey and store the source water pumped from the Mississippi River. Batch experiments, pilot-scale experiments, and model simulations were performed to determine the geosmin removal performance and bed life of a granular activated carbon (GAC) filter-sorber. Using batch adsorption isotherm parameters, the estimated bed life for the GAC filter-sorber ranged from 920 to 1241 days when challenged with a constant concentration of 100 ng/L of geosmin. The estimated bed life obtained using the AdDesignS model and the actual pilot-plant loading history was 594 days. Based on the pilot-scale GAC column data, the actual bed life (>714 days) was much longer than the simulated values because bed life was extended by biological degradation of geosmin. The continuous feeding of high concentrations of geosmin (100-400 ng/L) in the pilot-scale experiments enriched for a robust geosmin-degrading culture that was sustained when the geosmin feed was turned off for 40 days. It is unclear, however, whether a geosmin-degrading culture can be established in a full-scale filter that experiences taste and odor episodes for only 1 or 2 months per year. The results of this research indicate that care must be exercised in the design and interpretation of pilot-scale experiments and model simulations for predicting taste and odor removal in full-scale GAC filter-sorbers. Adsorption and the potential for biological degradation must be considered to estimate GAC bed life for the conditions of intermittent geosmin loading typically experienced by full-scale systems. (c) 2009 Elsevier Ltd. All rights reserved.

[Pilot-scale purification of lipopeptide from marine-derived Bacillus marinus].

PubMed

Gu, Kangbo; Guan, Cheng; Xu, Jiahui; Li, Shulan; Luo, Yuanchan; Shen, Guomin; Zhang, Daojing; Li, Yuanguang

2016-11-25

This research was aimed at establishing the pilot-scale purification technology of lipopeptide from marine-derived Bacillus marinus. We studied lipopeptide surfactivity interferences on scale-up unit technologies including acid precipitation, methanol extraction, solvent precipitation, salting out, extraction, silica gel column chromatography and HZ806 macroporous absorption resin column chromatography. Then, the unit technologies were combined in a certain order, to remove the impurities gradually, and to gain purified lipopeptide finally, with high recovery rate throughout the whole process. The novel pilot-scale purification technology could effectively isolate and purify lipopeptide with 87.51% to 100% purity in hectograms from 1 ton of Bacillus marinus B-9987 fermentation broth with more than 81.73% recovery rate. The first practical hectogram production of highly purified lipopeptide derived from Bacillus marinus was achieved. With this new purification method, using complex media became possible in fermentation process to reduce the fermentation cost and scale-up the purification for lipopeptide production. For practicability and economy, foaming problem resulting from massive water evaporation was avoided in this technology.

Evaluation of several biological monitoring techniques for hazard assessment of potentially contaminated wastewater and groundwater. Volume 3. Old O-field groundwater. Final report, July 1990-December 1991

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burton, D.T.; Turley, S.D.

1992-03-01

The toxicity of contaminated Old O-Field (Edgewood Area of Aberdeen Proving Ground) groundwater and the reduction and/or elimination of toxicity by various treatment processes were evaluated. The study was divided into a bench scale and pilot scale study. The bench scale studies consisted of 48-h definitive acute toxicity tests run with daphnid neonates (Daphnia magna) and juvenile fathead minnows (Pimephales promelas) exposed to untreated Old O-Field groundwater and groundwater treated by metals precipitation, UV oxidation (H 2O2 ), carbon adsorption, and carbon adsorption/biological sludge. The pilot scale studies consisted of several 96-h definitive acute toxicity tests run with two freshwatermore » and two saltwater invertebrates and fish and Ames mutagenicity assays. Acute toxicity tests were run on untreated Old O-Field groundwater and groundwater treated by metals precipitation, UV oxidation (H2O2), air stripping, and carbon adsorption during the pilot scale study. The freshwater invertebrate and fish used in the study were daphnid neonates and juvenile fathead minnows, respectively. The saltwater invertebrate and fish were juvenile mysids (Mysidopsis bahia) and juvenile sheepshead minnows (Cyprinodon variegatus). Ames tests were run on untreated groundwater, UV oxidation-treated groundwater, and carbon-treated groundwater.... Groundwater, Aquatic, Toxicity, Daphnia, Daphnia magna, Fathead minnow, Pimephales promelas, Mysid, Mysidopsis bahia, Sheepshead minnow, Cyprinodon variegatus.« less

SCALE-UP OF RAPID SMALL-SCALE ADSORPTION TESTS TO FIELD-SCALE ADSORBERS: THEORETICAL AND EXPERIMENTAL BASIS

EPA Science Inventory

Design of full-scale adsorption systems typically includes expensive and time-consuming pilot studies to simulate full-scale adsorber performance. Accordingly, the rapid small-scale column test (RSSCT) was developed and evaluated experimentally. The RSSCT can simulate months of f...

Immunogenicity and safety of the candidate RTS,S/AS01 vaccine in young Nigerian children: a randomized, double-blind, lot-to-lot consistency trial.

PubMed

Umeh, Rich; Oguche, Stephen; Oguonu, Tagbo; Pitmang, Simon; Shu, Elvis; Onyia, Jude-Tony; Daniyam, Comfort A; Shwe, David; Ahmad, Abdullahi; Jongert, Erik; Catteau, Grégory; Lievens, Marc; Ofori-Anyinam, Opokua; Leach, Amanda

2014-11-12

For regulatory approval, consistency in manufacturing of vaccine lots is expected to be demonstrated in confirmatory immunogenicity studies using two-sided equivalence trials. This randomized, double-blind study (NCT01323972) assessed consistency of three RTS,S/AS01 malaria vaccine batches formulated from commercial-scale purified antigen bulk lots in terms of anti-CS-responses induced. Healthy children aged 5-17 months were randomized (1:1:1:1) to receive RTS,S/AS01 at 0-1-2 months from one of three commercial-scale purified antigen bulk lots (1600 litres-fermentation scale; commercial-scale lots), or a comparator vaccine batch made from pilot-scale purified antigen bulk lot (20 litres-fermentation scale; pilot-scale lot). The co-primary objectives were to first demonstrate consistency of antibody responses against circumsporozoite (CS) protein at one month post-dose 3 for the three commercial-scale lots and second demonstrate non-inferiority of anti-CS antibody responses at one month post-dose 3 for the commercial-scale lots compared to the pilot-scale lot. Safety and reactogenicity were evaluated as secondary endpoints. One month post-dose-3, anti-CS antibody geometric mean titres (GMT) for the 3 commercial scale lots were 319.6 EU/ml (95% confidence interval (CI): 268.9-379.8), 241.4 EU/ml (207.6-280.7), and 302.3 EU/ml (259.4-352.3). Consistency for the RTS,S/AS01 commercial-scale lots was demonstrated as the two-sided 95% CI of the anti-CS antibody GMT ratio between each pair of lots was within the range of 0.5-2.0. GMT of the pooled commercial-scale lots (285.8 EU/ml (260.7-313.3)) was non-inferior to the pilot-scale lot (271.7 EU/ml (228.5-323.1)). Each RTS,S/AS01 lot had an acceptable tolerability profile, with infrequent reports of grade 3 solicited symptoms. No safety signals were identified and no serious adverse events were considered related to vaccination. RTS,S/AS01 lots formulated from commercial-scale purified antigen bulk batches induced a consistent anti-CS antibody response, and the anti-CS GMT of pooled commercial-scale lots was non-inferior to that of a lot formulated from a pilot-scale antigen bulk batch. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

Bicultural Work Motivation Scale for Asian American College Students

ERIC Educational Resources Information Center

Chen, Yung-Lung; Fouad, Nadya A.

2016-01-01

The bicultural work motivations of Asian Americans have not yet been comprehensively captured by contemporary vocational constructs and scales. For this study, we conducted two studies on the initial reliability and validity of the Bicultural Work Motivation Scale (BWMS) by combining qualitative and quantitative methods. First, a pilot study was…

A Scale-up Approach for Film Coating Process Based on Surface Roughness as the Critical Quality Attribute.

PubMed

Yoshino, Hiroyuki; Hara, Yuko; Dohi, Masafumi; Yamashita, Kazunari; Hakomori, Tadashi; Kimura, Shin-Ichiro; Iwao, Yasunori; Itai, Shigeru

2018-04-01

Scale-up approaches for film coating process have been established for each type of film coating equipment from thermodynamic and mechanical analyses for several decades. The objective of the present study was to establish a versatile scale-up approach for film coating process applicable to commercial production that is based on critical quality attribute (CQA) using the Quality by Design (QbD) approach and is independent of the equipment used. Experiments on a pilot scale using the Design of Experiment (DoE) approach were performed to find a suitable CQA from surface roughness, contact angle, color difference, and coating film properties by terahertz spectroscopy. Surface roughness was determined to be a suitable CQA from a quantitative appearance evaluation. When surface roughness was fixed as the CQA, the water content of the film-coated tablets was determined to be the critical material attribute (CMA), a parameter that does not depend on scale or equipment. Finally, to verify the scale-up approach determined from the pilot scale, experiments on a commercial scale were performed. The good correlation between the surface roughness (CQA) and the water content (CMA) identified at the pilot scale was also retained at the commercial scale, indicating that our proposed method should be useful as a scale-up approach for film coating process.

Preliminary Engineering Report for the Use of Peracetic Acid at the Oak Ridge National Laboratory Sewage Treatment Plant

DOE Office of Scientific and Technical Information (OSTI.GOV)

Taylor, Paul Allen

2017-02-01

The purpose of this report is to identify other disinfection methods to replace the current ozone system and propose a small pilot-scale test. Based on a review of the literature and disinfectants used by other wastewater plants in Tennessee, peracetic acid (PAA) was identified as a leading candidate. This report provides the basis for requesting approval for a pilot-scale study using PAA.

Prediction of Postpartum Social Support and Symptoms of Depression in Pregnant Adolescents: A Pilot Study

ERIC Educational Resources Information Center

Logsdon, M. Cynthia; Cross, Rene; Williams, Beverly; Simpson, Theresa

2004-01-01

Many pregnant adolescents remain in school, creating unique challenges for professionals to meet their educational and health needs. In this descriptive pilot study of pregnant adolescents (n = 26), 68% demonstrated symptoms of depression as measured by the Center for Epidemiologic Studies Depression Scale (CES-D). In addition, there was an…

Predicting self-construal from authoritarianism: a pilot study of perceived threat.

PubMed

Shaffer, Barbara A; Hollen, Ryan D; Hastings, Brad M

2007-12-01

This pilot study investigated the association of perceived threat and scores on a measure of Authoritarianism. Undergraduate students (29 women, 8 men; ages 18-32, M=21, SD=3.1), completed the Right-wing Authoritarianism scale and then the Self-construal scale after reading a nonthreatening or threatening news article. In the threatening condition, Authoritarian scores accounted for a significant amount of variance (R2= .26) in Interdependent Self-construal scores, but not for Independent Self-construal scores. No significant associations were found in the non-threatening condition.

Illuminating the "Boy Problem" from Children's and Teachers' Perspectives: A Pilot Study

ERIC Educational Resources Information Center

Hamilton, Paula Louise; Jones, Louise

2016-01-01

The apparent educational underperformance of boys has received phenomenal attention worldwide for many years. In the UK, it has led to various government reports and policies aimed at raising boys' achievement. This small-scale qualitative-interpretive pilot study, undertaken in one urban primary school in North Wales, reports the findings from…

The Effect of Journey around the World Curriculum on Prosocial Behavior in Elementary School Children: A Pilot Study

ERIC Educational Resources Information Center

Cha, Jae Seung

2017-01-01

This small-scale pilot study explored the effectiveness of proposed research instruments in measuring the outcomes of the prosocial and global education curriculum, "Journey Around the World" ("JAWD"), regarding attitudes toward school, affective language, prosocial motivation and behavior of second-grade school students.…

Effects of a multidisciplinary group rehabilitation programme on participation of the visually impaired elderly: a pilot study.

PubMed

Alma, Manna A; Groothoff, Johan W; Melis-Dankers, Bart J M; Post, Marcel W M; Suurmeijer, Theo P B M; van der Mei, Sijrike F

2012-01-01

To pilot test the newly developed multidisciplinary group rehabilitation programme Visually Impaired elderly Persons Participating (VIPP). A single group pretest-posttest design pilot study included 29 visually impaired persons (≥ 55 years). The intervention (20 weekly meetings) consisted of four components (practical training; education, social interaction, counselling and training of problem-solving skills; individual and group goal setting; home-based exercise programme). Participation was assessed with the Utrecht Scale for Evaluation of Rehabilitation-Participation (USER-P) and the Impact on Participation and Autonomy (IPA) questionnaire at baseline, immediately and 6 months after the intervention. At scale level, no statistical significant changes over time were found whereas the effect size indicated small effects for restrictions and satisfaction with participation, and a medium effect for autonomy outdoors. At item level, improvements tended to occur in frequency of housekeeping, in restrictions in housekeeping and outdoor activities and in satisfaction with the partner relationship. Satisfaction with leisure indoors and autonomy regarding using leisure time tended to increase as well. The tentative conclusion of this small-scale pilot study is that the VIPP programme modestly benefits perceived restrictions in participation, satisfaction with participation and autonomy outdoors of the visually impaired elderly. These preliminary findings warrant further investigation.

Creative use of pilot points to address site and regional scale heterogeneity in a variable-density model

USGS Publications Warehouse

Dausman, Alyssa M.; Doherty, John; Langevin, Christian D.

2010-01-01

Pilot points for parameter estimation were creatively used to address heterogeneity at both the well field and regional scales in a variable-density groundwater flow and solute transport model designed to test multiple hypotheses for upward migration of fresh effluent injected into a highly transmissive saline carbonate aquifer. Two sets of pilot points were used within in multiple model layers, with one set of inner pilot points (totaling 158) having high spatial density to represent hydraulic conductivity at the site, while a second set of outer points (totaling 36) of lower spatial density was used to represent hydraulic conductivity further from the site. Use of a lower spatial density outside the site allowed (1) the total number of pilot points to be reduced while maintaining flexibility to accommodate heterogeneity at different scales, and (2) development of a model with greater areal extent in order to simulate proper boundary conditions that have a limited effect on the area of interest. The parameters associated with the inner pilot points were log transformed hydraulic conductivity multipliers of the conductivity field obtained by interpolation from outer pilot points. The use of this dual inner-outer scale parameterization (with inner parameters constituting multipliers for outer parameters) allowed smooth transition of hydraulic conductivity from the site scale, where greater spatial variability of hydraulic properties exists, to the regional scale where less spatial variability was necessary for model calibration. While the model is highly parameterized to accommodate potential aquifer heterogeneity, the total number of pilot points is kept at a minimum to enable reasonable calibration run times.

Measure Twice, Build Once: Bench-Scale Testing to Evaluate Bioretention Media Design

EPA Science Inventory

The paper discusses the utility of conducting bench-scale testing on selected bioretention media and media amendments to validate hydrologic properties before installing media and amendments in larger pilot- or full-scale rain garden installations. The bench-scale study conclude...

Self-regulation workshop and Occupational Performance Coaching with teachers: A pilot study.

PubMed

Hui, Caroline; Snider, Laurie; Couture, Mélanie

2016-04-01

Teachers' occupational role and performance can be undermined when working with students with disruptive classroom behaviours. This pilot study aimed to explore the impact of school-based occupational therapy intervention on teachers' classroom management self-efficacy and perceived performance/satisfaction in their management of students with disruptive behaviours. This pilot study used a multiple-case replication study design. A cohort of regular classroom elementary school teachers (n = 11) participated in a 1-day workshop on sensorimotor strategies for supporting student self-regulation followed by eight individual sessions of Occupational Performance Coaching (OPC). Measurement tools were the Canadian Occupational Performance Measure, Goal Attainment Scaling (GAS), and Teachers' Self-Efficacy Scale-Classroom Management. Improvement in teachers' perception of performance, satisfaction, and classroom management was seen. GAS showed clinically significant improvement. Improvements were sustained at 7 weeks follow-up. Preliminary results support the use of sensorimotor education combined with OPC to enable teachers' occupational performance. © CAOT 2016.

GLYPHOSATE REMOVAL FROM DRINKING WATER

EPA Science Inventory

Activated-carbon, oxidation, conventional-treatment, filtration, and membrane studies are conducted to determine which process is best suited to remove the herbicide glyphosate from potable water. Both bench-scale and pilot-scale studies are completed. Computer models are used ...

Comparison of corrosion scales in full and partially replaced ...

EPA Pesticide Factsheets

Preliminary results from scales formed 38 weeks following the LSL replacement simulations revealed differences in scale formations amongst varying water qualities and pipe sequence. Rigs fed with dechlorinated tap water show distinct pH gradients between the galvanic and the background zones. Hydrocerussite and litharge are found both in field and pilot rigs. However, plumbonacrite, massicot, scrutinyite and plattnerite are only present in pipes harvested directly from the field. Laurionite, leadhillite, cerussite and calcite are found in rigs from the pilot. Cerussite is mostly present in the galvanic zones, close to the connection to the Cu pipe. Different types of scales are present in the rigs from the pilot and from the field, suggesting that differences in the formation in the scales and therefore differences in lead release from the pipes. The particulate Pb fraction in water samples is more important in samples from the pilot than from the field, median concentrations are 85X higher in partial LSL and 10X higher in full LSL in the pilot. Lead phosphates are present in the scales from the rigs treated with orthophosphate. Complete results will be obtained by the end of July 2016. The main objective is to compare scales from full and partial LSLs harvested from the field and from a pilot setup fed with water from the same distribution system and subjected to water quality changes.

Pilot Scale Production and Testing of a Recombinant Staphylococcal Enterotoxin (SEB) Triple Mutant

DTIC Science & Technology

2017-09-01

1 PILOT-SCALE PRODUCTION AND TESTING OF A RECOMBINANT STAPHYLOCOCCAL ENTEROTOXIN (SEB) TRIPLE MUTANT ECBC...Disclaimer The findings in this report are not to be construed as an official Department of the Army position unless so designated by other authorizing...TYPE Final 3. DATES COVERED (From - To) Mar 2010 – Dec 2011 4. TITLE AND SUBTITLE Pilot-Scale Production and Testing of a Recombinant

Service Quality Assessment Scale (SQAS): An Instrument for Evaluating Service Quality of Health-Fitness Clubs

ERIC Educational Resources Information Center

Lam, Eddie T. C.; Zhang, James J.; Jensen, Barbara E.

2005-01-01

This study was designed to develop the Service Quality Assessment Scale to evaluate the service quality of health-fitness clubs. Through a review of literature, field observations, interviews, modified application of the Delphi technique, and a pilot study, a preliminary scale with 46 items was formulated. The preliminary scale was administered to…

Texas Urban Triangle : pilot study to implement a spatial decision support system (SDSS) for sustainable mobility.

DOT National Transportation Integrated Search

2011-03-01

This project addressed sustainable transportation in the Texas Urban Triangle (TUT) by conducting a pilot : project at the county scale. The project tested and developed the multi-attribute Spatial Decision Support : System (SDSS) developed in 2009 u...

Pilot-scale tests of HEME and HEPA dissolution process

DOE Office of Scientific and Technical Information (OSTI.GOV)

Qureshi, Z.H.; Strege, D.K.

A series of pilot-scale demonstration tests for the dissolution of High Efficiency Mist Eliminators (HEME`s) and High Efficiency Particulate Airfilters (HEPA) were performed on a 1/5th linear scale. These fiberglass filters are to be used in the Defense Waste Processing Facility (DWPF) to decontaminate the effluents from the off-gases generated during the feed preparation process and vitrification. When removed, these filters will be dissolved in the Decontamination Waste Treatment Tank (DWTT) using 5 wt% NaOH solution. The contaminated fiberglass is converted to an aqueous stream which will be transferred to the waste tanks. The filter metal structure will be rinsedmore » with process water before its disposal as low-level solid waste. The pilot-scale study reported here successfully demonstrated a simple one step process using 5 wt% NaOH solution. The proposed process requires the installation of a new water spray ring with 30 nozzles. In addition to the reduced waste generated, the total process time is reduced to 48 hours only (66% saving in time). The pilot-scale tests clearly demonstrated that the dissolution process of HEMEs has two stages - chemical digestion of the filter and mechanical erosion of the digested filter. The digestion is achieved by a boiling 5 wt% caustic solutions, whereas the mechanical break down of the digested filter is successfully achieved by spraying process water on the digested filter. An alternate method of breaking down the digested filter by increased air sparging of the solution was found to be marginally successful are best. The pilot-scale tests also demonstrated that the products of dissolution are easily pumpable by a centrifugal pump.« less

Effects of Reiki on Pain, Anxiety, and Blood Pressure in Patients Undergoing Knee Replacement: A Pilot Study.

PubMed

Baldwin, Ann Linda; Vitale, Anne; Brownell, Elise; Kryak, Elizabeth; Rand, William

This blinded, controlled pilot study investigated the effects of Reiki on 46 patients undergoing knee replacement surgery. Of the 3 groups, Reiki, Sham Reiki, and Standard of Care, only the Reiki group showed significant reductions in pain, blood pressure, respiration rate, and state anxiety, which provides evidence for a full-scale clinical study.

Careers of Professional Staff in Australian and UK Universities: A Mixed Methods Pilot Study

ERIC Educational Resources Information Center

Gander, Michelle

2017-01-01

This article confirms the reliability of a protean and boundaryless career attitudes scale, tested in a pilot study. Additionally, it summarises the results of this study into the career attitudes of professional staff in Australian and UK universities. A mixed methods approach was taken using a survey consisting of both closed questions on a…

Performance evaluation of a pilot-scale anaerobic membrane bioreactor (AnMBR) treating ethanol thin stillage.

PubMed

Dereli, R K; Urban, D R; Heffernan, B; Jordan, J A; Ewing, J; Rosenberger, G T; Dunaev, T I

2012-01-01

The ethanol industry has grown rapidly during the past ten years, mainly due to increasing oil prices. However, efficient and cost-effective solutions for treating thin stillage wastewater have still to be developed. The anaerobic membrane bioreactor (AnMBR) technology combines classical anaerobic treatment in a completely-stirred tank reactor (CSTR) with membrane separation. The combination of these two technologies can achieve a superior effluent quality and also increase biogas production compared to conventional anaerobic solutions. A pilot-scale AnMBR treating thin stillage achieved very high treatment efficiencies in terms of chemical oxygen demand (COD) and total suspended solids (TSS) removal (>98%). An average permeate flux of 4.3 L/m2 x h was achieved at relatively low transmembrane pressure (TMP) values (0.1-0.2 bars) with flat-sheet membranes. Experience gained during the pilot-scale studies provides valuable information for scaling up of AnMBRs treating complex and high-strength wastewaters.

Determining the Influence of Groundwater Composition on the Performance of Arsenic Adsorption Columns Using Rapid Small-Scale Column Tests

NASA Astrophysics Data System (ADS)

Aragon, A. R.; Siegel, M.

2004-12-01

The USEPA has established a more stringent drinking water standard for arsenic, reducing the maximum contaminant level (MCL) from 50 μ g/L to 10 μ g/L. This will affect many small communities in the US that lack the appropriate treatment infrastructure and funding to reduce arsenic to such levels. For such communities, adsorption systems are the preferred technology based on ease of operation and relatively lower costs. The performance of adsorption media for the removal of arsenic from drinking water is dependent on site-specific water quality. At certain concentrations, co-occurring solutes will compete effectively with arsenic for sorption sites, potentially reducing the sorption capacity of the media. Due to the site-specific nature of water quality and variations in media properties, pilot scale studies are typically carried out to ensure that a proposed treatment technique is cost effective before installation of a full-scale system. Sandia National Laboratories is currently developing an approach to utilize rapid small-scale columns in lieu of pilot columns to test innovative technologies that could significantly reduce the cost of treatment in small communities. Rapid small-scale column tests (RSSCTs) were developed to predict full-scale treatment of organic contaminants by adsorption onto granular activated carbon (GAC). This process greatly reduced the time and costs required to verify performance of GAC adsorption columns. In this study, the RSSCT methodology is used to predict the removal of inorganic arsenic using mixed metal oxyhydroxide adsorption media. The media are engineered and synthesized from materials that control arsenic behavior in natural and disturbed systems. We describe the underlying theory and application of RSSCTs for the performance evaluation of novel media in several groundwater compositions. Results of small-scale laboratory columns are being used to predict the performance of pilot-scale systems and ultimately to design full-scale systems. RSSCTs will be performed on a suite of water compositions representing the variety of water supplies in the United States that are affected by the new drinking water standard. Ultimately, this approach will be used to carry out inexpensive short-term pilot studies at a large number of sites where large-scale pilots are not economically feasible. Sandia National Laboratories is a multi-program laboratory operated by Sandia Corporation, a Lockheed Martin company, for the United States Department of Energy's National Nuclear Security Administration under Contract DE-AC04-94AL85000.

Grid-Enabled Quantitative Analysis of Breast Cancer

DTIC Science & Technology

2010-10-01

large-scale, multi-modality computerized image analysis . The central hypothesis of this research is that large-scale image analysis for breast cancer...research, we designed a pilot study utilizing large scale parallel Grid computing harnessing nationwide infrastructure for medical image analysis . Also

Development of the Attributed Dignity Scale.

PubMed

Jacelon, Cynthia S; Dixon, Jane; Knafl, Kathleen A

2009-07-01

A sequential, multi-method approach to instrument development beginning with concept analysis, followed by (a) item generation from qualitative data, (b) review of items by expert and lay person panels, (c) cognitive appraisal interviews, (d) pilot testing, and (e) evaluating construct validity was used to develop a measure of attributed dignity in older adults. The resulting positively scored, 23-item scale has three dimensions: Self-Value, Behavioral Respect-Self, and Behavioral Respect-Others. Item-total correlations in the pilot study ranged from 0.39 to 0.85. Correlations between the Attributed Dignity Scale (ADS) and both Rosenberg's Self-Esteem Scale (0.17) and Crowne and Marlowe's Social Desirability Scale (0.36) were modest and in the expected direction, indicating attributed dignity is a related but independent concept. Next steps include testing the ADS with a larger sample to complete factor analysis, test-retest stability, and further study of the relationships between attributed dignity and other concepts.

The Poverty and Housing Scale: report on a pilot study.

PubMed

Galambos, Colleen M; MacMaster, Samuel A

2004-01-01

The measurement of beliefs and attitudes on poverty and housing is important to researchers and social workers interested in examining the role that belief structures have on the development of policy and programs in these areas. This article reports pilot study findings of a new scale, The Poverty and Housing Scale (PHS), that measures this concept and evaluates its psychometric properties. Preliminary reliability was in the very good range. Examinations of content and face validity provided support of the instrument as a valid measure of beliefs and attitudes on poverty and housing. The factor analysis emerged a one factor, 13-item scale. Unlike other related scales, the PHS attempts to link the social factor of poverty and housing together. Theoretical and methodological strengths and weaknesses are considered and the implications for social work practice are discussed. The authors provide recommendations for additional testing of the instrument.

RELATIONSHIPS BETWEEN LABORATORY AND PILOT-SCALE COMBUSTION OF SOME CHLORINATED HYDROCARBONS

EPA Science Inventory

Factors governing the occurence of trace amounts of residual organic substance emmissions (ROSEs) in full-scale incierators are not fully understood. Pilot-scale spray combustion expereiments involving some liquid chlorinated hydrocarbons (CHCs) and their dilute mixtures with hy...

Large Pilot-Scale Carbon Dioxide (CO2) Capture Project Using Aminosilicone Solvent.Final Scientific/Technical Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hancu, Dan

GE Global Research has developed, over the last 8 years, a platform of cost effective CO2 capture technologies based on a non-aqueous aminosilicone solvent (GAP-1m). As demonstrated in previous funded DOE projects (DE-FE0007502 and DEFE0013755), the GAP-1m solvent has increased CO2 working capacity, lower volatility and corrosivity than the benchmark aqueous amine technology. Performance of the GAP-1m solvent was recently demonstrated in a 0.5 MWe pilot at National Carbon Capture Center, AL with real flue gas for over 500 hours of operation using a Steam Stripper Column (SSC). The pilot-scale PSTU engineering data were used to (i) update the techno-economicmore » analysis, and EH&S assessment, (ii) perform technology gap analysis, and (iii) conduct the solvent manufacturability and scale-up study.« less

Impact of temperature on nitrification in biological activated carbon (BAC) filters used for drinking water treatment.

PubMed

Andersson, A; Laurent, P; Kihn, A; Prévost, M; Servais, P

2001-08-01

The impact of temperature on nitrification in biological granular activated carbon (GAC) filters was evaluated in order to improve the understanding of the nitrification process in drinking water treatment. The study was conducted in a northern climate where very cold water temperatures (below 2 degrees C) prevail for extended periods and rapid shifts of temperature are frequent in the spring and fall. Ammonia removals were monitored and the fixed nitrifying biomass was measured using a method of potential nitrifying activity. The impact of temperature was evaluated on two different filter media: an opened superstructure wood-based activated carbon and a closed superstructure activated carbon-based on bituminous coal. The study was conducted at two levels: pilot scale (first-stage filters) and full-scale (second-stage filters) and the results indicate a strong temperature impact on nitrification activity. Ammonia removal capacities ranged from 40 to 90% in pilot filters, at temperatures above 10 degrees C, while more than 90% ammonia was removed in the full-scale filters for the same temperature range. At moderate temperatures (4-10 degrees C), the first stage pilot filters removed 10-40% of incoming ammonia for both media (opened and closed superstructure). In the full-scale filters, a difference between the two media in nitrification performances was observed at moderate temperatures: the ammonia removal rate in the opened superstructure support (more than 90%) was higher than in the closed superstructure support (45%). At low temperatures (below 4 degrees C) both media performed poorly. Ammonia removal capacities were below 30% in both pilot- and full-scale filters.

A dual-task home-based rehabilitation programme for improving balance control in patients with acquired brain injury: a single-blind, randomized controlled pilot study.

PubMed

Peirone, Eliana; Goria, Paolo Filiberto; Anselmino, Arianna

2014-04-01

To evaluate the safety, feasibility and effectiveness of a dual-task home-based rehabilitation programme on balance impairments among adult patients with acquired brain injury. Single-blind, randomized controlled pilot study. Single rehabilitation centre. Sixteen participants between 12 and 18 months post-acquired brain injury with balance impairments and a score <10 seconds on the One-Leg Stance Test (eyes open). All participants received 50-minutes individualised traditional physiotherapy sessions three times a week for seven weeks. In addition, the intervention group (N = 8) performed an individualised dual-task home-based programme six days a week for seven weeks. The primary outcome measure was the Balance Evaluation System Test; secondary measures were the Activities-specific Balance Confidence Scale and Goal Attainment Scaling. At the end of the pilot study, the intervention group showed significantly greater improvement in Balance Evaluation System Test scores (17.87, SD 6.05) vs. the control group (5.5, SD 3.53; P = 0.008, r = 0.63). There was no significant difference in improvement in Activities-specific Balance Confidence Scale scores between the intervention group (25.25, SD 25.51) and the control group (7.00, SD 14.73; P = 0.11, r = 0.63). There was no significant improvement in Goal Attainment Scaling scores in the intervention (19.37, SD 9.03) vs. the control group (16.28, SD 6.58; P = 0.093, r = 0.63). This pilot study shows the safety, feasibility and short-term benefit of a dual-task home-based rehabilitation programme to improve balance control in patients with acquired brain injury. A sample size of 26 participants is required for a definitive study.

TASK 2: QUENCH ZONE SIMULATION

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fusselman, Steve

Aerojet Rocketdyne (AR) has developed an innovative gasifier concept incorporating advanced technologies in ultra-dense phase dry feed system, rapid mix injector, and advanced component cooling to significantly improve gasifier performance, life, and cost compared to commercially available state-of-the-art systems. A key feature of the AR gasifier design is the transition from the gasifier outlet into the quench zone, where the raw syngas is cooled to ~ 400°C by injection and vaporization of atomized water. Earlier pilot plant testing revealed a propensity for the original gasifier outlet design to accumulate slag in the outlet, leading to erratic syngas flow from themore » outlet. Subsequent design modifications successfully resolved this issue in the pilot plant gasifier. In order to gain greater insight into the physical phenomena occurring within this zone, AR developed a cold flow simulation apparatus with Coanda Research & Development with a high degree of similitude to hot fire conditions with the pilot scale gasifier design, and capable of accommodating a scaled-down quench zone for a demonstration-scale gasifier. The objective of this task was to validate similitude of the cold flow simulation model by comparison of pilot-scale outlet design performance, and to assess demonstration scale gasifier design feasibility from testing of a scaled-down outlet design. Test results did exhibit a strong correspondence with the two pilot scale outlet designs, indicating credible similitude for the cold flow simulation device. Testing of the scaled-down outlet revealed important considerations in the design and operation of the demonstration scale gasifier, in particular pertaining to the relative momentum between the downcoming raw syngas and the sprayed quench water and associated impacts on flow patterns within the quench zone. This report describes key findings from the test program, including assessment of pilot plant configuration simulations relative to actual results on the pilot plant gasifier and demonstration plant design recommendations, based on cold flow simulation results.« less

Fenton-Driven Chemical Regeneration of MTBE-Spent Granular Activated Carbon -- A Pilot Study

EPA Science Inventory

MTBE-spent granular activated carbon (GAC) underwent 3 adsorption/oxidation cycles. Pilot-scale columns were intermittently placed on-line at a ground water pump and treat facility, saturated with MTBE, and regenerated with H2O2 under different chemical, physical, and operational...

PILOT PLANT STUDY OF CONVERSION OF COAL TO LOW SULFUR FUEL

EPA Science Inventory

The report gives results of a program to develop, on bench and pilot scales, operating conditions for the key step in the IGT process to desulfurize coal by thermal and chemical treatment. This process, to date, uses the 'sulfur-getter' concept. (A sulfur-getter is a material tha...

Biological treatment of whey by Tetrahymena pyriformis and impact study on laboratory-scale wastewater lagoon process.

PubMed

Bonnet, J L; Bogaerts, P; Bohatier, J

1999-06-01

A procedure based on a biological treatment of whey was tested as part of research on waste treatment at the scale of small cheesemaking units. We studied the potential biodegradation of whey by a protozoan ciliate, Tetrahymena pyriformis, and evaluated the functional, microbiological and physiological disturbances caused by crude whey and the biodegraded whey in laboratory-scale pilots mimicking a natural lagoon treatment. The results show that T. pyriformis can strongly reduce the pollutant load of whey. In the lagoon pilots serving as example of receptor media, crude whey gradually but completely arrested operation, whereas with the biodegraded whey adverse effects were only temporary, and normal operation versus a control was gradually recovered in a few days.

Study of the Influence of Key Process Parameters on Furfural Production.

PubMed

Fele Žilnik, Ljudmila; Grilc, Viktor; Mirt, Ivan; Cerovečki, Željko

2016-01-01

The present work reports the influence of key process variables on the furfural formation from leached chestnut-wood chips in a pressurized reactor. Effect of temperature, pressure, type and concentration of the catalyst solution, the steam flow rate or stripping module, the moisture content of the wood particles and geometric characteristics such as size and type of the reactor, particle size and bed height were considered systematically. One stage process was only taken into consideration. Lab-scale and pilot-scale studies were performed. The results of the non-catalysed laboratory experiments were compared with an actual non-catalysed (auto-catalysed) industrial process and with experiments on the pilot scale, the latter with 28% higher furfural yield compared to the others. Application of sulphuric acid as catalyst, in an amount of 0.03-0.05 g (H2SO4 100%)/g d.m. (dry material), enables a higher production of furfural at lower temperature and pressure of steam in a shorter reaction time. Pilot scale catalysed experiments have revealed very good performance for furfural formation under less severe operating conditions, with a maximum furfural yield as much as 88% of the theoretical value.

Effect of matured compost as an inoculating agent on odour removal and maturation of vegetable and fruit waste compost.

PubMed

Chen, Chih-Yu; Kuo, Jong-Tar; Chung, Ying-Chien

2013-01-01

The use of matured compost as an inoculation agent to improve the composting of vegetable and fruit wastes in a laboratory-scale composter was evaluated, and the commercial feasibility of this approach in a pilot-scale (1.8 x 10(4) L) composter was subsequently confirmed. The effect of aeration rate on the physico-chemical and biological properties of compost was also studied. Aeration rate affected the fermentation temperature, moisture content, pH, O2 consumption rate, CO2 production rate and the formation of odour. The optimal aeration rate was 2.5 L air/kg dry solid/min. The CO2 production rate approached the theoretical value during composting and was linearly dependent on temperature, indicating that the compost system had good operating characteristics. The inoculation of cellulolytic bacteria and deodorizing bacteria to compost in the pilot-scale composter led to an 18.2% volatile solids loss and a 64.3% volume reduction ratio in 52 h; only 1.5 ppm(v) odour was detected. This is the first study to focus on both operating performance and odour removal in a pilot-scale composter.

Early language screening in city and Hackney: the concurrent validity of a measure designed for use with 2 1/2-year-olds.

PubMed

Law, J

1994-01-01

This paper reports data relating to the development of a screening test for language impairment in 2 1/2-year-old children. The screening test itself has previously been described. The results of a pilot study and a larger community study are reported. In all, 34 children were included in the pilot study and 1015 in the community study. The reference test selected was the Reynell Developmental Language Scales and the cut-off adopted 1.5 standard deviations below the mean for either the expressive or the receptive scale of the test concerned. The pass mark on the screening test was ascertained using receiver operating characteristics (ROC). The validity is reported given the cut-off identified. The specificity, sensitivity and both positive and negative predictive abilities are reported for both the pilot and the subsequent study. The application of the test is discussed in the context of the current debate about early identification.

Integration of visual and motion cues for simulator requirements and ride quality investigation. [computerized simulation of aircraft landing, visual perception of aircraft pilots

NASA Technical Reports Server (NTRS)

Young, L. R.

1975-01-01

Preliminary tests and evaluation are presented of pilot performance during landing (flight paths) using computer generated images (video tapes). Psychophysiological factors affecting pilot visual perception were measured. A turning flight maneuver (pitch and roll) was specifically studied using a training device, and the scaling laws involved were determined. Also presented are medical studies (abstracts) on human response to gravity variations without visual cues, acceleration stimuli effects on the semicircular canals, and neurons affecting eye movements, and vestibular tests.

Pilot-scale ISCO treatment of a MtBE contaminated site using a Fenton-like process.

PubMed

Innocenti, Ivan; Verginelli, Iason; Massetti, Felicia; Piscitelli, Daniela; Gavasci, Renato; Baciocchi, Renato

2014-07-01

This paper reports about a pilot-scale feasibility study of In-Situ Chemical Oxidation (ISCO) application based on the use of stabilized hydrogen peroxide catalyzed by naturally occurring iron minerals (Fenton-like process) to a site formerly used for fuel storage and contaminated by MtBE. The stratigraphy of the site consists of a 2-3 meter backfill layer followed by a 3-4 meter low permeability layer, that confines the main aquifer, affected by a widespread MtBE groundwater contamination with concentrations up to 4000 μg/L, also with the presence of petroleum hydrocarbons. The design of the pilot-scale treatment was based on the integration of the results obtained from experimental and numerical modeling accounting for the technological and regulatory constraints existing in the site to be remediated. In particular, lab-scale batch tests allowed the selection of the most suitable operating conditions. Then, this information was implemented in a numerical software that allowed to define the injection and monitoring layout and to predict the propagation of hydrogen peroxide in groundwater. The pilot-scale field results confirmed the effective propagation of hydrogen peroxide in nearly all the target area (around 75 m(2) using 3 injection wells). As far as the MtBE removal is concerned, the ISCO application allowed us to meet the clean-up goals in an area of 60 m(2). Besides, the concentration of TBA, i.e. a potential by-product of MtBE oxidation, was actually reduced after the ISCO treatment. The results of the pilot-scale test suggest that ISCO may be a suitable option for the remediation of the groundwater plume contaminated by MtBE, providing the background data for the design and cost-estimate of the full-scale treatment. Copyright © 2014 Elsevier B.V. All rights reserved.

Need for Achievement, Curiosity and Sense of Control: Pilot Study for a Large-Scale Investigation.

ERIC Educational Resources Information Center

Greenberger, Ellen; Entwisle, Doris R.

The introduction reviews a number of findings and problems in the measurement of achievement motivation and raises some questions concerning the possible friction between motivation to achieve and curiosity. Subjects for the two pilot studies es were ninth graders of average (95-113) and high IQ (128 +) from a predominantly upper middle-class…

Binary constructs of forensic psychiatric nursing: a pilot study.

PubMed

Mason, T; Dulson, J; King, L

2009-03-01

The aim was to develop an Information Gathering Schedule (IGS) relevant to forensic psychiatric nursing in order to establish the perceived differences in the three levels of security, high, medium and low. Perceived differences in the role constructs of forensic psychiatric nursing is said to exist but the evidence is qualitative or anecdotal. This paper sets out a pilot study beginning in 2004 relating to the development of two rating scales for inclusion into an IGS to acquire data on the role constructs of nurses working in these environments. Following a thematic analysis from the literature two sets of binary frameworks were constructed and a number of questions/statements relating to them were tested. The Thurstone Scaling test was applied to compute medians resulting in a reduction to 48 and 20 items for each respective framework. Two 7-point Likert scales were constructed and test-retest procedures were applied on a sample population of forensic psychiatric nurses. Student's t-test was conducted on the data and the results suggest that the IGS is now suitable for application on a larger study. The IGS was piloted on a small sample of forensic psychiatric nurses. The two scales were validated to coefficient values ranging from 0.7 to 0.9. Amendments were made and the IGS was considered acceptable.

Smouldering Remediation (STAR) Technology: Field Pilot Tests and First Full Scale Application

NASA Astrophysics Data System (ADS)

Gerhard, J.; Kinsman, L.; Torero, J. L.

2015-12-01

STAR (Self-sustaining Treatment for Active Remediation) is an innovative remediation technology based on the principles of smoldering combustion where the contaminants are the fuel. The self-sustaining aspect means that a single, local ignition event can result in many days of contaminant destruction in situ. Presented research to date has focused on bench scale experiments, numerical modelling and process understanding. Presented here is the maturation of the in situ technology, including three field pilot tests and a full-scale implementation to treat coal tar-impacted soils. The first pilot determined a Radius of Influence (ROI) for a single ignition of approximately eight feet with an average propagation rate of the reaction of approximately one foot per day. TPH concentrations in soils were reduced from 10,000 milligrams per kilogram to a few hundred milligrams per kilogram. The second pilot was conducted in an area of significant void spaces created through the anthropogenic deposition of clay bricks and tiles. The void spaces led to pre-mature termination of the combustion reaction, limiting ROI and the effectiveness of the technology in this setting. The third case study involved the pilot testing, design, and full-scale implementation of STAR at a 37-acre former chemical manufacturing facility. Three phases of pilot testing were conducted within two hydrogeologic units at the site (i.e., surficial fill and deep alluvial sand units). Pilot testing within the fill demonstrated self-sustained coal tar destruction rates in excess of 800 kg/day supported through air injection at a single well. Deep sand unit testing (twenty-five feet below the water table) resulted in the treatment of a targeted six-foot layer of impacted fine sands to a radial distance of approximately twelve feet. These results (and additional parameters) were used to develop a full-scale STAR design consisting of approximately 1500 surficial fill ignition points and 500 deep sand ignition points and two treatment (air distribution and vapor collection / treatment) systems to remediate an approximately 14-acre footprint of contaminated soils within the project timelines (i.e., by mid-2016). Field activities began in 2014 and progress is currently on-schedule.

Developing an instrument for assessing fidelity of motivational care planning: The Aboriginal and Islander Mental health initiative adherence scale.

PubMed

Prowse, Phuong-Tu; Nagel, Tricia

2014-01-01

The aim of this study was to design and trial an Adherence Scale to measure fidelity of Motivational Care Planning (MCP) within a clinical trial. This culturally adapted therapy MCP uses a client centered holistic approach that emphasises family and culture to motivate healthy life style changes. The Motivational Care Planning-Adherence Scale (MCP-AS) was developed through consultation with Aboriginal and Islander Mental Health Initiative (AIMhi) Indigenous and non-Indigenous trainers, and review of MCP training resources. The resultant ten-item scale incorporates a 9-Point Likert Scale with a supporting protocol manual and uses objective, behaviourally anchored criteria for each scale point. A fidelity assessor piloted the tool through analysis of four audio-recordings of MCP (conducted by Indigenous researchers within a study in remote communities in Northern Australia). File audits of the remote therapy sessions were utilised as an additional source of information. A Gold Standard Motivational Care Planning training video was also assessed using the MCP-AS. The Motivational Care Planning-Adherence Scale contains items measuring both process and content of therapy sessions. This scale was used successfully to assess therapy through observation of audio or video-recorded sessions and review of clinical notes. Treatment fidelity measured by the MCP-AS within the pilot study indicated high fidelity ratings. Ratings were high across the three domains of rapport, motivation, and self-management with especially high ratings for positive feedback and engagement, review of stressors and goal setting. The Motivational Care Planning-Adherence Scale has the potential to provide a measure of quality of delivery of Motivation Care Planning. The pilot findings suggest that despite challenges within the remote Indigenous community setting, Indigenous therapists delivered therapy that was of high fidelity. While developed as a research tool, the scale has the potential to support fidelity of delivery of Motivation Care Planning in clinical, supervision and training settings. Larger studies are needed to establish inter-rater reliability and internal and external validity.

Pilot-Scale Treatment of Virginia Canyon Mine Drainage in Idaho Springs, Colorado, USA Using Octolig®

EPA Science Inventory

Water quality data from the pilot study are compared to the specific project objectives to evaluate performance of the treatment technology relative to the needs of EPA Region 8. Project objectives included meeting site-specific water quality criteria for Al, Cd, Cu, Pb, and Zn;...

WASHING STUDIES FOR PCP AND CREOSOTE-CONTAMINATED SOIL

EPA Science Inventory

The Environmental Protection Agency has conducted a series of bench-scale and pilot-scale studies to evaluate the feasibility of washing pentachlorophenol (PCP) and creosote from the soil at an abandoned wood-treatment Superfund site in Pensacola, FL. The high sand content and lo...

INTEGRATION OF PHOTOCATALYTIC OXIDATION WITH AIR STRIPPING OF CONTAMINATED AQUIFERS

EPA Science Inventory

Bench scale laboratory studies and pilot scale studies in a simulated field-test situation were performed to evaluate the integration of gas-solid ultaviolet (UV) photocatalytic oxidation (PCO) downstream if an air stripper unit as a technology for cost-effectively treating water...

Solar photocatalytic degradation of some hazardous water-soluble pesticides at pilot-plant scale.

PubMed

Oller, I; Gernjak, W; Maldonado, M I; Pérez-Estrada, L A; Sánchez-Pérez, J A; Malato, S

2006-12-01

The technical feasibility and performance of photocatalytic degradation of six water-soluble pesticides (cymoxanil, methomyl, oxamyl, dimethoate, pyrimethanil and telone) have been studied at pilot-plant scale in two well-defined systems which are of special interest because natural solar UV light can be used: heterogeneous photocatalysis with titanium dioxide and homogeneous photocatalysis by photo-Fenton. TiO(2) photocatalysis tests were performed in a 35L solar pilot plant with three Compound Parabolic Collectors (CPCs) under natural illumination and a 75L solar pilot plant with four CPC units was used for homogeneous photocatalysis tests. The initial pesticide concentration studied was 50 mg L(-1) and the catalyst concentrations employed were 200 mg L(-1) of TiO(2) and 20 mg L(-1) of iron. Both toxicity (Vibrio fischeri, Biofix) and biodegradability (Zahn-Wellens test) of the initial pesticide solutions were also measured. Total disappearance of the parent compounds and nearly complete mineralization were attained with all pesticides tested. Treatment time, hydrogen peroxide consumption and release of heteroatoms are discussed.

Pilot scale dilute acid pretreatment of rice straw and fermentable sugar recovery at high solid loadings.

PubMed

Kapoor, Manali; Soam, Shveta; Agrawal, Ruchi; Gupta, Ravi P; Tuli, Deepak K; Kumar, Ravindra

2017-01-01

The aim of this work was to study the dilute acid pretreatment of rice straw (RS) and fermentable sugar recovery at high solid loadings at pilot scale. A series of pretreatment experiments were performed on RS resulting in >25wt% solids followed by enzymatic hydrolysis without solid-liquid separation at 20 and 25wt% using 10FPU/g of the pretreated residue. The overall sugar recovery including the sugars released in pretreatment and enzymatic hydrolysis was calculated along with a mass balance. Accordingly, the optimized conditions, i.e. 0.35wt% acid, 162°C and 10min were identified. The final glucose and xylose concentrations obtained were 83.3 and 31.9g/L respectively resulting in total concentration of 115.2g/L, with a potential to produce >50g/L of ethanol. This is the first report on pilot scale study on acid pretreatment of RS in a screw feeder horizontal reactor followed by enzymatic hydrolysis at high solid loadings. Copyright © 2016 Elsevier Ltd. All rights reserved.

Coaching as Part of a Pilot Quality Rating Scale Initiative: Challenges to--and Supports for--the Change-Making Process

ERIC Educational Resources Information Center

Ackerman, Debra J.

2008-01-01

Several nonprofit agencies in a large Midwestern city provide assistance to early care and education programs participating in a pilot Quality Rating Scale (QRS) initiative by pairing them with itinerant consultants, who are known as coaches. Despite this assistance, not all programs improve their QRS score. Furthermore, while pilot stakeholders…

Urdu translation and validation of shorter version of Positive Affect and Negative Affect Schedule (PANAS) on Pakistani bank employees.

PubMed

Akhter, Noreen

2017-10-01

To translate, adapt and validate shorter version of positive affect and negative affect scale on Pakistani corporate employees. This cross-sectional study was conducted in the twin cities of Islamabad and Rawalpindi from October 2014 to December 2015. The study was completed into two independent parts. In part one, the scale was translated by forward translation. Then it was pilot-tested and administered on customer services employees from commercial banks and the telecommunication sector. Data of the pilot study was analysed by using exploratory factor analysis to extract the initial factor of positive affect and negative affect scale. Part two comprised the main study. Commercial bank employees were included in the sample using convenient sampling technique. Data of the main study was analysed using confirmatory factor analysis in order to establish construct validity of positive affect and negative affect scale. There were145 participants in the first part of the study and 495 in the second. Results of confirmatory factor analysis confirmed the two-factor structure of positive affect and negative affect scale suggesting that the scale has two distinct domains, i.e. positive affect and negative affect. The shorter version of positive affect and negative affect scale was found to be a valid and reliable measure.

Removal of bromide and bromate from drinking water using granular activated carbon.

PubMed

Zhang, Yong-Qing; Wu, Qing-Ping; Zhang, Ju-Mei; Yang, Xiu-Hua

2015-03-01

Granular activated carbon (GAC) was used to remove bromide (Br⁻) and bromate (BrO(3)(-)) from drinking water in both bench- and pilot-scale experiments. The present study aims to minimize BrO(3)(-) formation and eliminate BrO(3)(-) generated during the ozonation of drinking water, particularly in packaged drinking water. Results show that the Br⁻ and BrO(3)(-) levels in GAC-treated water decreased in both bench- and pilot-scale experiments. In the bench-scale experiments, when the empty bed contact time (EBCT) was 5 min, the highest reduction rates of Br(-) in the mineral and ultrapure water were found to be 74.9% and 91.2%, respectively, and those of BrO(3)(-) were 94.4% and 98.8%, respectively. The GAC capacity for Br⁻ and BrO(3)(-) removal increased with the increase in EBCT. Reduction efficiency was better in ultrapure water than in mineral water. In the pilot-scale experiments, the minimum reduction rates of Br⁻ and BrO(3)(-) were 38.5% and 73.2%, respectively.

Development of a Measure of Mood State for Children: The MINIMOOD

ERIC Educational Resources Information Center

Lynch, Mervin D.; Foley-Peres, Kathleen; Sullivan, Stefanie

2008-01-01

The purposes of the present study were to develop and validate a mood scale measure for elementary grade school children. Graduate students generated a sampling of mood state items, 30 to use in a pilot study and 60 to use in a study to develop and validate this scale. Ratings were obtained on five point scale choices on each of the items from a…

Demonstrating Functional Equivalence of Pilot and Production Scale Freeze-Drying of BCG

PubMed Central

ten Have, R.; Reubsaet, K.; van Herpen, P.; Kersten, G.; Amorij, J.-P.

2016-01-01

Process analytical technology (PAT)-tools were used to monitor freeze-drying of Bacille Calmette-Guérin (BCG) at pilot and production scale. Among the evaluated PAT-tools, there is the novel use of the vacuum valve open/close frequency for determining the endpoint of primary drying at production scale. The duration of primary drying, the BCG survival rate, and the residual moisture content (RMC) were evaluated using two different freeze-drying protocols and were found to be independent of the freeze-dryer scale evidencing functional equivalence. The absence of an effect of the freeze-dryer scale on the process underlines the feasibility of the pilot scale freeze-dryer for further BCG freeze-drying process optimization which may be carried out using a medium without BCG. PMID:26981867

Demonstrating Functional Equivalence of Pilot and Production Scale Freeze-Drying of BCG.

PubMed

Ten Have, R; Reubsaet, K; van Herpen, P; Kersten, G; Amorij, J-P

2016-01-01

Process analytical technology (PAT)-tools were used to monitor freeze-drying of Bacille Calmette-Guérin (BCG) at pilot and production scale. Among the evaluated PAT-tools, there is the novel use of the vacuum valve open/close frequency for determining the endpoint of primary drying at production scale. The duration of primary drying, the BCG survival rate, and the residual moisture content (RMC) were evaluated using two different freeze-drying protocols and were found to be independent of the freeze-dryer scale evidencing functional equivalence. The absence of an effect of the freeze-dryer scale on the process underlines the feasibility of the pilot scale freeze-dryer for further BCG freeze-drying process optimization which may be carried out using a medium without BCG.

Integrated care pilot in north-west London: a mixed methods evaluation

PubMed Central

Curry, Natasha; Harris, Matthew; Gunn, Laura H.; Pappas, Yannis; Blunt, Ian; Soljak, Michael; Mastellos, Nikolaos; Holder, Holly; Smith, Judith; Majeed, Azeem; Ignatowicz, Agnieszka; Greaves, Felix; Belsi, Athina; Costin-Davis, Nicola; Jones Nielsen, Jessica D.; Greenfield, Geva; Cecil, Elizabeth; Patterson, Susan; Car, Josip; Bardsley, Martin

2013-01-01

Introduction This paper provides the results of a year-long evaluation of a large-scale integrated care pilot in north-west London. The pilot aimed to integrate care across primary, acute, community, mental health and social care for people with diabetes and/or those aged 75+ through care planning, multidisciplinary case reviews, information sharing and project management support. Methods The evaluation team conducted qualitative studies of change at organisational, clinician and patient levels (using interviews, focus groups and a survey); and quantitative analysis of change in service use and patient-level clinical outcomes (using patient-level datasets and a matched control study). Results The pilot had successfully engaged provider organisations, created a shared strategic vision and established governance structures. However, the engagement of clinicians was variable and there was no evidence to date of significant reductions in emergency admissions. There was some evidence of changes in care processes. Conclusion Although the pilot has demonstrated the beginnings of large-scale change, it remains in the early stages and faces significant challenges as it seeks to become sustainable for the longer term. It is critical that National Health Service managers and clinicians have realistic expectations of what can be achieved in a relatively short period of time. PMID:24167455

Methylphenidate in the management of asthenia in breast cancer patients treated with docetaxel: results of a pilot study.

PubMed

Cueva, Juan F; Calvo, Marcos; Anido, Urbano; León, Luis; Gallardo, Elena; Areses, Carmen; Bernárdez, Beatriz; Gayoso, Lucía; García, Jorge; Jesús Lamas, María; Curiel, Teresa; Vázquez, Francisca; Candamio, Sonia; Vidal, Yolanda; Javier Barón, Francisco; López, Rafael

2012-04-01

The objectives of this pilot study were to evaluate the safety and efficacy of the central nervous system stimulant methylphenidate in the management of asthenia in breast cancer patients treated with docetaxel. Patients with early breast cancer who presented asthenia >3 on the Visual Analogue Scale (VAS) after the first cycle of docetaxel-based chemotherapy were included. Patients received two additional cycles of chemotherapy, one with methylphenidate (10 mg bid) and the other without methylphenidate. Asthenia was evaluated using VAS and the Functional Assessment of Cancer Therapy-Fatigue (FACT-F) scale. Distress was assessed using the Hospital Anxiety and Depression Scale (HADS), and quality of life using FACT-F. Ten patients were included and evaluated for efficacy and safety. Overall, cycles with methylphenidate were better tolerated than those without methylphenidate in terms of asthenia (VAS, p = 0.004; FACT-F, p = 0.027) and quality of life (FACT-F, p = 0.047). No significant differences were observed in terms of distress (HADS, p = 0.297). Six (60%) patients continued with methylphenidate after study end. Main adverse events during study were palpitations and insomnia (30% of patients each). This pilot study suggests that methylphenidate may reduce asthenia and improve quality of life in breast cancer patients treated with docetaxel.

Pilot study of a targeted dance class for physical rehabilitation in children with cerebral palsy.

PubMed

López-Ortiz, Citlali; Egan, Tara; Gaebler-Spira, Deborah J

2016-01-01

This pilot study evaluates the effects of a targeted dance class utilizing classical ballet principles for rehabilitation of children with cerebral palsy on balance and upper extremity control. Twelve children with cerebral palsy (ages 7-15 years) with Gross Motor Function Classification scores II-IV participated in this study and were assigned to either a control group or targeted dance class group. Targeted dance class group participated in 1-h classes three times per week in a 4-week period. The Pediatric Balance Scale and the Quality of Upper Extremity Skills Test were administered before, after, and 1 month after the targeted dance class. Improvements in the Pediatric Balance Scale were present in the targeted dance class group in before versus after and before versus 1 month follow-up comparisons (p-value = 0.0088 and p-value = 0.019, respectively). The Pediatric Balance Scale changes were not significant in the control group. The Quality of Upper Extremity Skills Test did not reach statistical differences in either group. Classical ballet as an art form involves physical training, musical accompaniment, social interactions, and emotional expression that could serve as adjunct to traditional physical therapy. This pilot study demonstrated improvements in balance control. A larger study with a more homogeneous sample is warranted.

A pilot rating scale for evaluating failure transients in electronic flight control systems

NASA Technical Reports Server (NTRS)

Hindson, William S.; Schroeder, Jeffery A.; Eshow, Michelle M.

1990-01-01

A pilot rating scale was developed to describe the effects of transients in helicopter flight-control systems on safety-of-flight and on pilot recovery action. The scale was applied to the evaluation of hardovers that could potentially occur in the digital flight-control system being designed for a variable-stability UH-60A research helicopter. Tests were conducted in a large moving-base simulator and in flight. The results of the investigation were combined with existing airworthiness criteria to determine quantitative reliability design goals for the control system.

An ultra scale-down approach to study the interaction of fermentation, homogenization, and centrifugation for antibody fragment recovery from rec E. coli.

PubMed

Li, Qiang; Mannall, Gareth J; Ali, Shaukat; Hoare, Mike

2013-08-01

Escherichia coli is frequently used as a microbial host to express recombinant proteins but it lacks the ability to secrete proteins into medium. One option for protein release is to use high-pressure homogenization followed by a centrifugation step to remove cell debris. While this does not give selective release of proteins in the periplasmic space, it does provide a robust process. An ultra scale-down (USD) approach based on focused acoustics is described to study rec E. coli cell disruption by high-pressure homogenization for recovery of an antibody fragment (Fab') and the impact of fermentation harvest time. This approach is followed by microwell-based USD centrifugation to study the removal of the resultant cell debris. Successful verification of this USD approach is achieved using pilot scale high-pressure homogenization and pilot scale, continuous flow, disc stack centrifugation comparing performance parameters such as the fraction of Fab' release, cell debris size distribution and the carryover of cell debris fine particles in the supernatant. The integration of fermentation and primary recovery stages is examined using USD monitoring of different phases of cell growth. Increasing susceptibility of the cells to disruption is observed with time following induction. For a given recovery process this results in a higher fraction of product release and a greater proportion of fine cell debris particles that are difficult to remove by centrifugation. Such observations are confirmed at pilot scale. Copyright © 2013 Wiley Periodicals, Inc.

On the relation between personality and job performance of airline pilots.

PubMed

Hormann, H J; Maschke, P

1996-01-01

The validity of a personality questionnaire for the prediction of job success of airline pilots is compared to validities of a simulator checkflight and of flying experience data. During selection, 274 pilots applying for employment with a European charter airline were examined with a multidimensional personality questionnaire (Temperature Structure Scales; TSS). Additionally, the applicants were graded in a simulator checkflight. On the basis of training records, the pilots were classified as performing at standard or below standard after about 3 years of employment in the hiring company. In a multiple-regression model, this dichotomous criterion for job success can be predicted with 73.8% accuracy through the simulator checkflight and flying experience prior to employment. By adding the personality questionnaire to the regression equation, the number of correct classifications increases to 79.3%. On average, successful pilots score substantially higher on interpersonal scales and lower on emotional scales of the TSS.

SUPERFUND TREATABILITY CLEARINGHOUSE: COMPOSITING EXPLOSIVES/ORGANICS CONTAMINATED SOILS

EPA Science Inventory

Laboratory scale and pilot scale studies were conducted to evaluate composting to treat sediments and soils containing explosive and organic compounds. Sediment and soil from lagoons at Army ammunition plants, located in Louisiana, Wisconsin and Pennsylvania contained high...

The effects of clinical aromatherapy for anxiety and depression in the high risk postpartum woman - a pilot study.

PubMed

Conrad, Pam; Adams, Cindy

2012-08-01

The aim of this study was to determine if aromatherapy improves anxiety and/or depression in the high risk postpartum woman and to provide a complementary therapy tool for healthcare practitioners. The pilot study was observational with repeated measures. Private consultation room in a Women's center of a large Indianapolis hospital. 28 women, 0-18 months postpartum. The treatment groups were randomized to either the inhalation group or the aromatherapy hand m'technique. Treatment consisted of 15 min sessions, twice a week for four consecutive weeks. An essential oil blend of rose otto and lavandula angustifolia @ 2% dilution was used in all treatments. The non-randomized control group, comprised of volunteers, was instructed to avoid aromatherapy use during the 4 week study period. Allopathic medical treatment continued for all participants. All subjects completed the Edinburgh Postnatal Depression Scale (EPDS) and Generalized Anxiety Disorder Scale (GAD-7) at the beginning of the study. The scales were then repeated at the midway point (two weeks), and at the end of all treatments (four weeks). Analysis of Variance (ANOVA) was utilized to determine differences in EPDS and/or GAD-7 scores between the aromatherapy and control groups at baseline, midpoint and end of study. No significant differences were found between aromatherapy and control groups at baseline. The midpoint and final scores indicated that aromatherapy had significant improvements greater than the control group on both EPDS and GAD-7 scores. There were no adverse effects reported. The pilot study indicates positive findings with minimal risk for the use of aromatherapy as a complementary therapy in both anxiety and depression scales with the postpartum woman. Future large scale research in aromatherapy with this population is recommended. Copyright © 2012 Elsevier Ltd. All rights reserved.

Prevalence of fatigue in a group of airline pilots.

PubMed

Reis, Cátia; Mestre, Catarina; Canhão, Helena

2013-08-01

Fatigue is a common phenomenon in airline pilots that can impair alertness and ability of crewmembers to safely operate an aircraft and perform safety related tasks. Fatigue can increase the risk of an incident or even an accident. This study provides the first prevalence values for clinically significant fatigue in Portuguese airline pilots. The hypothesis that medium/short-haul pilots may currently present different levels of fatigue than long-haul pilots was also tested. A survey was conducted by requesting Portuguese airline pilots to complete questionnaires placed in the pilots' personal lockers from 1 April until 15 May 2012. The questionnaire included the self-response Fatigue Severity Scale (FSS) to measure subjective fatigue and some additional questions concerning perception of fatigue by pilots. The prevalence values for total and mental fatigue achieved in the Portuguese airline pilots were: 89.3% (FSS > or = 4) and 94.1% (FSS > or = 4) when splitting the sample in two subsamples, long- and medium/short-haul pilots. Levels of total and mental fatigue were higher for medium/short-haul pilots. The analysis of fatigue levels in each type of aviator showed that medium/short-haul pilots presented the highest levels of total and mental fatigue. This study produced the first prevalence values of total and mental fatigue among Portuguese airline pilots, which represents a great step to understanding and addressing this critical phenomenon.

Lessons from a pilot program to induce stove replacements in Chile: design, implementation and evaluation

NASA Astrophysics Data System (ADS)

Gómez, Walter; Chávez, Carlos; Salgado, Hugo; Vásquez, Felipe

2017-11-01

We present the design, implementation, and evaluation of a subsidy program to introduce cleaner and more efficient household wood combustion technologies. The program was conducted in the city of Temuco, one of the most polluted cities in southern Chile, as a pilot study to design a new national stove replacement initiative for pollution control. In this city, around 90% of the total emissions of suspended particulate matter is caused by households burning wood. We created a simulated market in which households could choose among different combustion technologies with an assigned subsidy. The subsidy was a relevant factor in the decision to participate, and the inability to secure credit was a significant constraint for the participation of low-income households. Due to several practical difficulties and challenges associated with the implementation of large-scale programs that encourage technological innovation at the household level, it is strongly advisable to start with a small-scale pilot that can provide useful insights into the final design of a fuller, larger-scale program.

Pilot-scale road subbase made with granular material formulated with MSWI bottom ash and stabilized APC fly ash: environmental impact assessment.

PubMed

del Valle-Zermeño, R; Formosa, J; Prieto, M; Nadal, R; Niubó, M; Chimenos, J M

2014-02-15

A granular material (GM) to be used as road sub-base was formulated using 80% of weathered bottom ash (WBA) and 20% of mortar. The mortar was prepared separately and consisted in 50% APC and 50% of Portland cement. A pilot-scale study was carried on by constructing three roads in order to environmentally evaluate the performance of GM in a real scenario. By comparing the field results with those of the column experiments, the overestimations observed at laboratory scale can be explained by the potential mechanisms in which water enters into the road body and the pH of the media. An exception was observed in the case of Cu, whose concentration release at the test road was higher. The long-time of exposure at atmospheric conditions might have favoured oxidation of organic matter and therefore the leaching of this element. The results obtained showed that immobilization of all heavy metals and metalloids from APC is achieved by the pozzolanic effect of the cement mortar. This is, to the knowledge of the authors, the only pilot scale study that is considering reutilization of APC as a safe way to disposal. Copyright © 2013 Elsevier B.V. All rights reserved.

Ultra scale-down device to predict dewatering levels of solids recovered in a continuous scroll decanter centrifuge.

PubMed

Lopes, A G; Keshavarz-Moore, E

2013-01-01

During centrifugation operation, the major challenge in the recovery of extracellular proteins is the removal of the maximum liquid entrapped within the spaces between the settled solids-dewatering level. The ability of the scroll decanter centrifuge (SDC) to process continuously large amounts of feed material with high concentration of solids without the need for resuspension of feeds, and also to achieve relatively high dewatering, could be of great benefit for future use in the biopharmaceutical industry. However, for reliable prediction of dewatering in such a centrifuge, tests using the same kind of equipment at pilot-scale are required, which are time consuming and costly. To alleviate the need of pilot-scale trials, a novel USD device, with reduced amounts of feed (2 mL) and to be used in the laboratory, was developed to predict the dewatering levels of a SDC. To verify USD device, dewatering levels achieved were plotted against equivalent compression (Gtcomp ) and decanting (Gtdec ) times, obtained from scroll rates and feed flow rates operated at pilot-scale, respectively. The USD device was able to successfully match dewatering trends of the pilot-scale as a function of both Gtcomp and Gtdec , particularly for high cell density feeds, hence accounting for all key variables that influenced dewatering in a SDC. In addition, it accurately mimicked the maximum dewatering performance of the pilot-scale equipment. Therefore the USD device has the potential to be a useful tool at early stages of process development to gather performance data in the laboratory thus minimizing lengthy and costly runs with pilot-scale SDC. © 2013 American Institute of Chemical Engineers.

Medical student and junior doctors' tolerance of ambiguity: development of a new scale.

PubMed

Hancock, Jason; Roberts, Martin; Monrouxe, Lynn; Mattick, Karen

2015-03-01

The practice of medicine involves inherent ambiguity, arising from limitations of knowledge, diagnostic problems, complexities of treatment and outcome and unpredictability of patient response. Research into doctors' tolerance of ambiguity is hampered by poor conceptual clarity and inadequate measurement scales. We aimed to create and pilot a measurement scale for tolerance of ambiguity in medical students and junior doctors that addresses the limitations of existing scales. After defining tolerance of ambiguity, scale items were generated by literature review and expert consultation. Feedback on the draft scale was sought and incorporated. 411 medical students and 75 foundation doctors in Exeter, UK were asked to complete the scale. Psychometric analysis enabled further scale refinement and comparison of scale scores across subgroups. The pilot study achieved a 64% response rate. The final 29 item version of the Tolerance of Ambiguity in Medical Students and Doctors (TAMSAD) scale had good internal reliability (Cronbach's α 0.80). Tolerance of ambiguity was higher in foundation year 2 doctors than first, third and fourth year medical students (-5.23, P = 0.012; -5.98, P = 0.013; -4.62, P = 0.035, for each year group respectively). The TAMSAD scale offers a valid and reliable alternative to existing scales. Further work is required in different settings and in longitudinal studies but this study offers intriguing provisional insights.

Pilot-scale study on the treatment of basal aquifer water using ultrafiltration, reverse osmosis and evaporation/crystallization to achieve zero-liquid discharge.

PubMed

Loganathan, Kavithaa; Chelme-Ayala, Pamela; Gamal El-Din, Mohamed

2016-01-01

Basal aquifer water is deep groundwater found at the bottom of geological formations, underlying bitumen-saturated sands. Some of the concerns associated with basal aquifer water at the Athabasca oil sands are the high concentrations of hardness-causing compounds, alkalinity, and total dissolved solids. The objective of this pilot-scale study was to treat basal aquifer water to a quality suitable for its reuse in the production of synthetic oil. To achieve zero-liquid discharge (ZLD) conditions, the treatment train included chemical oxidation, polymeric ultrafiltration (UF), reverse osmosis (RO), and evaporation-crystallization technologies. The results indicated that the UF unit was effective in removing solids, with UF filtrate turbidity averaging 2.0 NTU and silt density index averaging 0.9. Membrane autopsies indicated that iron was the primary foulant on the UF and RO membranes. Laboratory and pilot-scale tests on RO reject were conducted to determine the feasibility of ZLD crystallization. Due to the high amounts of calcium, magnesium, and bicarbonate in the RO reject, softening of the feed was required to avoid scaling in the evaporator. Crystals produced throughout the testing were mainly sodium chloride. The results of this study indicated that the ZLD approach was effective in both producing freshwater and minimizing brine discharges. Copyright © 2015 Elsevier Ltd. All rights reserved.

CSC Tip Sheets: Conducting and Evaluating Pilot Projects

EPA Pesticide Factsheets

Learn how to conduct and evaluate pilot projects, which are opportunities to “test the waters” for your project on a small scale, provide insight and data on what works, and adjust your strategy for full-scale implementation.

ORGANIC EMISSIONS FROM PILOT-SCALE INCINERATION OF CFCS

EPA Science Inventory

The paper gives results of the characterization of organic emissions resulting from the pilot-scale incineration of trichlorofluoromethane (CFC-11) and dichlorodifluoromethane (CFC-12) under varied feed concentrations. (NOTE: As a result of the Montreal Protocol, an international...

PILOT SCALE REACTOR FOR ELECTROCHEMICAL DECHLORINATION OF MODEL CHLORINATED CONTAMINANTS

EPA Science Inventory

Electrochemical degradation (ECD) is a promising technology for in-situ remediation of diversely contaminated submarine matrices, by the application of low level DC electric fields. This study, prompted by successful bench-scale electrochemical dechlorination of Trichloroe...

Development of a Metaconceptual Awareness and Regulation Scale

ERIC Educational Resources Information Center

Kirbulut, Zubeyde Demet; Uzuntiryaki-Kondakci, Esen; Beeth, Michael Edward

2016-01-01

This study aimed to develop the Metaconceptual Awareness and Regulation Scale (MARS) -- a self-report instrument for measuring the extent to which students realise, monitor, and evaluate their ideas. MARS consists of 10 items scored on a six-point Likert scale for two factors: metaconceptual awareness and metaconceptual regulation. A pilot study…

Improving Marital Prediction: A Model and a Pilot Study.

ERIC Educational Resources Information Center

Dean, Dwight G.; Lucas, Wayne L.

A model for the prediction of marital adjustment is proposed which presents selected social background factors (e.g., education) and interactive factors (e.g., Bienvenu's Communication scale, Hurvitz' Role Inventory, Dean's Emotional Maturity and Commitment scales, Rosenberg's Self-Esteem scale) in order to account for as much of the variance in…

Energy performance evaluation of ultrasonic pretreatment of organic solid waste in a pilot-scale digester.

PubMed

Rasapoor, Mazdak; Adl, Mehrdad; Baroutian, Saeid; Iranshahi, Zeynab; Pazouki, Mohammad

2018-04-30

It has been proven that ultrasonic pretreatment (UP) has positive effect on biogas generation from previous lab-scale studies. However, that is not always the case in larger scale processes. The purpose of this study was to evaluate the effectiveness of UP to biogas generation in terms of anaerobic digestion process and energy efficiency. Parameters including total solids (TS) and ultrasonic treatment operational parameters of organic solid waste (OSW) resulted from our past lab scale UP studies were applied in this study. OSW with 6-10% TS was treated using a lab-scale ultrasonic processor using various power densities (0.2-0.6 W/mL) at different time periods up to 30 min. Results of lab scale confirmed that OSW with 6% TS sonicated with 0.2 W/mL power density in 30 min gave the best outcome for the pilot scale experiment. To simulate the condition of an actual scale, in addition to energy analysis, two different organic loading rates (OLR), namely 500 and 1500 gVS/m 3 day were examined. The pilot digester was fed with OSW with or without the pretreatment based on the aforementioned specifications. The results showed that UP effectively improves biogas generation in terms of quantity and quality (CH 4 /CO 2 ). Furthermore, it decreases the time to reach the maximum cumulative biogas volume comparing to the untreated feed. The key achievement of this research has confirmed that although the relative increase in the energy gain by the influence of UP was more remarkable under the 500 gVS/m 3 day OLR, energy analysis showed a better energy gain and energy benefit as well as jumping in biogas yield up to 80% for UP treated OSW under 1500 gVS/m 3 day OLR. Copyright © 2018 Elsevier B.V. All rights reserved.

Reviewing and piloting methods for decreasing discount rates; someone, somewhere in time.

PubMed

Parouty, Mehraj B Y; Krooshof, Daan G M; Westra, Tjalke A; Pechlivanoglou, Petros; Postma, Maarten J

2013-08-01

There has been substantial debate on the need for decreasing discounting for monetary and health gains in economic evaluations. Next to the discussion on differential discounting, a way to identify the need for such discounting strategies is through eliciting the time preferences for monetary and health outcomes. In this article, the authors investigate the perceived time preference for money and health gains through a pilot survey on Dutch university students using methods on functional forms previously suggested. Formal objectives of the study were to review such existing methods and to pilot them on a convenience sample using a questionnaire designed for this specific purpose. Indeed, a negative relation between the time of delay and the variance of the discounting rate for all models was observed. This study was intended as a pilot for a large-scale population-based investigation using the findings from this pilot on wording of the questionnaire, interpretation, scope and analytic framework.

Defining Feasibility and Pilot Studies in Preparation for Randomised Controlled Trials: Development of a Conceptual Framework.

PubMed

Eldridge, Sandra M; Lancaster, Gillian A; Campbell, Michael J; Thabane, Lehana; Hopewell, Sally; Coleman, Claire L; Bond, Christine M

2016-01-01

We describe a framework for defining pilot and feasibility studies focusing on studies conducted in preparation for a randomised controlled trial. To develop the framework, we undertook a Delphi survey; ran an open meeting at a trial methodology conference; conducted a review of definitions outside the health research context; consulted experts at an international consensus meeting; and reviewed 27 empirical pilot or feasibility studies. We initially adopted mutually exclusive definitions of pilot and feasibility studies. However, some Delphi survey respondents and the majority of open meeting attendees disagreed with the idea of mutually exclusive definitions. Their viewpoint was supported by definitions outside the health research context, the use of the terms 'pilot' and 'feasibility' in the literature, and participants at the international consensus meeting. In our framework, pilot studies are a subset of feasibility studies, rather than the two being mutually exclusive. A feasibility study asks whether something can be done, should we proceed with it, and if so, how. A pilot study asks the same questions but also has a specific design feature: in a pilot study a future study, or part of a future study, is conducted on a smaller scale. We suggest that to facilitate their identification, these studies should be clearly identified using the terms 'feasibility' or 'pilot' as appropriate. This should include feasibility studies that are largely qualitative; we found these difficult to identify in electronic searches because researchers rarely used the term 'feasibility' in the title or abstract of such studies. Investigators should also report appropriate objectives and methods related to feasibility; and give clear confirmation that their study is in preparation for a future randomised controlled trial designed to assess the effect of an intervention.

Proteus DSA control room in Mojave, CA

NASA Image and Video Library

2003-04-03

Proteus DSA control room in Mojave, CA (L to R) Jean-Pierre Soucy; Amphitech International Software engineer Craig Bomben; NASA Dryden Test Pilot Pete Siebold; (with headset, at computer controls) Scaled Composites pilot Bob Roehm; New Mexico State University (NMSU) UAV Technical Analysis Application Center (TAAC) Chuck Coleman; Scaled Composites Pilot Kari Sortland; NMSU TAAC Russell Wolfe; Modern Technology Solutions, Inc. Scaled Composites' unique tandem-wing Proteus was the testbed for a series of UAV collision-avoidance flight demonstrations. An Amphitech 35GHz radar unit installed below Proteus' nose was the primary sensor for the Detect, See and Avoid tests.

National Alliance for Advance Biofuels and Bio-Products Final Technical Report Addendum Hydrothermal Processing Pilot System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Oyler, James R.

2015-12-21

The main objective of the NAABB was to combine science, technology, and engineering expertise from across the nation to break down critical technical barriers to commercialization of algae-based biofuels. As a part of the consortium, Genifuel’s NAABB goals was to fabricate and demonstrate a pilot-scale system to convert algae into fuels. The purpose of this pilot system was to show that processes developed in the laboratory at bench-scale during the program could be successfully scaled up to a pre-commercial level, and thereby provide visibility into the ultimate viability and cost of algae biofuels. The pilot system has now been completedmore » and tested, and this report documents what has been achieved.« less

Ultrasonic pilot-scale reactor for enzymatic bleaching of cotton fabrics.

PubMed

Gonçalves, Idalina; Herrero-Yniesta, Victor; Perales Arce, Iratxe; Escrigas Castañeda, Monica; Cavaco-Paulo, Artur; Silva, Carla

2014-07-01

The potential of ultrasound-assisted technology has been demonstrated by several laboratory scale studies. However, their successful industrial scaling-up is still a challenge due to the limited pilot and commercial sonochemical reactors. In this work, a pilot reactor for laccase-hydrogen peroxide cotton bleaching assisted by ultrasound was scaled-up. For this purpose, an existing dyeing machine was transformed and adapted by including piezoelectric ultrasonic devices. Laboratory experiments demonstrated that both low frequency, high power (22 kHz, 2100 W) and high frequency, low power ultrasounds (850 kHz, 400 W) were required to achieve satisfactory results. Standard half (4 g/L H2O2 at 90 °C for 60 min) and optical (8 g/L H2O2 at 103 °C for 40 min) cotton bleaching processes were used as references. Two sequential stages were established for cotton bleaching: (1) laccase pretreatment assisted by high frequency ultrasound (850 kHz, 400 W) and (2) bleaching using high power ultrasound (22 kHz, 2100 W). When compared with conventional methods, combined laccase-hydrogen peroxide cotton bleaching with ultrasound energy improved the whitening effectiveness. Subsequently, less energy (temperature) and chemicals (hydrogen peroxide) were needed for cotton bleaching thus resulting in costs reduction. This technology allowed the combination of enzyme and hydrogen peroxide treatment in a continuous process. The developed pilot-scale reactor offers an enhancement of the cotton bleaching process with lower environmental impact as well as a better performance of further finishing operations. Copyright © 2014 Elsevier B.V. All rights reserved.

Field Testing of a Wet FGD Additive for Enhanced Mercury Control - Pilot-Scale Test Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gary M. Blythe

2006-03-01

This Topical Report summarizes progress on Cooperative Agreement DE-FC26-04NT42309, ''Field Testing of a Wet FGD Additive.'' The objective of the project is to demonstrate the use of a flue gas desulfurization (FGD) additive, Degussa Corporation's TMT-15, to prevent the reemissions of elemental mercury (Hg{sup 0}) in flue gas exiting wet FGD systems on coal-fired boilers. Furthermore, the project intends to demonstrate that the additive can be used to precipitate most of the mercury (Hg) removed in the wet FGD system as a fine TMT salt that can be separated from the FGD liquor and bulk solid byproducts for separate disposal.more » The project will conduct pilot and full-scale tests of the TMT-15 additive in wet FGD absorbers. The tests are intended to determine required additive dosage requirements to prevent Hg{sup 0} reemissions and to separate mercury from the normal FGD byproducts for three coal types: Texas lignite/Power River Basin (PRB) coal blend, high-sulfur Eastern bituminous coal, and low-sulfur Eastern bituminous coal. The project team consists of URS Group, Inc., EPRI, TXU Generation Company LP, Southern Company, and Degussa Corporation. TXU Generation has provided the Texas lignite/PRB co-fired test site for pilot FGD tests, Monticello Steam Electric Station Unit 3. Southern Company is providing the low-sulfur Eastern bituminous coal host site for wet scrubbing tests, as well as the pilot and full-scale jet bubbling reactor (JBR) FGD systems to be tested. A third utility, to be named later, will provide the high-sulfur Eastern bituminous coal full-scale FGD test site. Degussa Corporation is providing the TMT-15 additive and technical support to the test program. The project is being conducted in six tasks. Of the six project tasks, Task 1 involves project planning and Task 6 involves management and reporting. The other four tasks involve field testing on FGD systems, either at pilot or full scale. The four tasks include: Task 2 - Pilot Additive Testing in Texas Lignite Flue Gas; Task 3 - Full-scale FGD Additive Testing in High Sulfur Eastern Bituminous Flue Gas; Task 4 - Pilot Wet Scrubber Additive Tests at Yates; and Task 5 - Full-scale Additive Tests at Plant Yates. This topical report presents the results from the Task 2 and Task 4 pilot-scale additive tests. The Task 3 and Task 5 full-scale additive tests will be conducted later in calendar year 2006.« less

The Development of the Meta-Affective Trait Scale

ERIC Educational Resources Information Center

Uzuntiryaki-Kondakci, Esen; Kirbulut, Zubeyde Demet

2016-01-01

The purpose of this study was to develop a Meta-Affective Trait Scale (MATS) to measure the meta-affective inclinations related to emotions that students have while they are studying for their classes. First, a pilot study was performed with 380 10th-grade students. Results of the exploratory factor analysis supported a two-factor structure of the…

The Effects of a Performance Base Curriculum on the Gross Motor Development of Preschool Children during Teacher Training: A Pilot Study.

ERIC Educational Resources Information Center

van der Mars, Hans; Butterfield, Stephen A.

This pilot study used a task-analyzed performance base curriculum as an intervention on the gross motor development of 24 children aged three to six, 15 in a treatment group, 9 in a control group. Pre- and post-training data on gross motor development (relating to 10 motor skills) were collected using the Ohio State University Scale of Intra Gross…

Large-scale preparation of clove essential oil and eugenol-loaded liposomes using a membrane contactor and a pilot plant.

PubMed

Sebaaly, Carine; Greige-Gerges, Hélène; Agusti, Géraldine; Fessi, Hatem; Charcosset, Catherine

2016-01-01

Based on our previous study where optimal conditions were defined to encapsulate clove essential oil (CEO) into liposomes at laboratory scale, we scaled-up the preparation of CEO and eugenol (Eug)-loaded liposomes using a membrane contactor (600 mL) and a pilot plant (3 L) based on the principle of ethanol injection method, both equipped with a Shirasu Porous Glass membrane for injection of the organic phase into the aqueous phase. Homogenous, stable, nanometric-sized and multilamellar liposomes with high phospholipid, Eug loading rates and encapsulation efficiency of CEO components were obtained. Saturation of phospholipids and drug concentration in the organic phase may control the liposome stability. Liposomes loaded with other hydrophobic volatile compounds could be prepared at large scale using the ethanol injection method and a membrane for injection.

Exploring the Interrelationship of Structure and Process in Family Child Care: The FCCERS-R and "Combined" CLASS

ERIC Educational Resources Information Center

Enns, Lionel

2012-01-01

This study examined the correlations between two prominent family child care environmental rating scales, the Family Child Care Environment Rating Scale - Revised (FCCERS-R) and the "Combined" Classroom Assessment Scoring System ("Combined" CLASS), both of which were used during the pilot study of Washington State's Quality…

SITE EMERGING TECHNOLOGY SUMMARY: INTEGRATION OF PHOTOCATALYTIC OXIDATION WITH AIR STRIPPING OF CONTAMINATED AQUIFERS

EPA Science Inventory

In a recently completed test program, bench-scale laboratory studies at Arizona State University (ASU) in Tempe, AZ, and pilot-scale studies in a simulated field test situation at Zentox Corp in Ocala, FL, were performed to evaluate the integration of gas-solid ultraviolet (UV) p...

Development and Validation of Information Technology Mentor Teacher Attitude Scale: A Pilot Study

ERIC Educational Resources Information Center

Saltan, Fatih

2015-01-01

The aim of this study development and validation of a teacher attitude scale toward Information Technology Mentor Teachers (ITMT). ITMTs give technological support to other teachers for integration of technology in their lessons. In the literature, many instruments have been developed to measure teachers' attitudes towards the technological tools…

Chemical additive to maximize antimicrobial effect of chlorine during pilot scale immersion chilling of broiler carcasses

USDA-ARS?s Scientific Manuscript database

A prior laboratory scale study demonstrated the potential for T-128, a proprietary blend including propylene glycol and phosphoric acid, to enhance the antimicrobial efficacy of chlorine during immersion chilling of broiler parts. The objective of the current study was to test the addition of T-128...

The Development and Validation of the Instructional Dissent Scale

ERIC Educational Resources Information Center

Goodboy, Alan K.

2011-01-01

Two studies (N = 420) were conducted to develop and validate the instructional dissent scale (IDS) for use in the college classroom. Participants in study 1 were 210 students who completed the IDS pilot inventory which was subjected to an exploratory factor analysis yielding three distinct factors of dissent (i.e., expressive, rhetorical,…

Introduction of Syphilis Point-of-Care Tests, from Pilot Study to National Programme Implementation in Zambia: A Qualitative Study of Healthcare Workers' Perspectives on Testing, Training and Quality Assurance.

PubMed

Ansbro, Éimhín M; Gill, Michelle M; Reynolds, Joanna; Shelley, Katharine D; Strasser, Susan; Sripipatana, Tabitha; Tshaka Ncube, Alexander; Tembo Mumba, Grace; Terris-Prestholt, Fern; Peeling, Rosanna W; Mabey, David

2015-01-01

Syphilis affects 1.4 million pregnant women globally each year. Maternal syphilis causes congenital syphilis in over half of affected pregnancies, leading to early foetal loss, pregnancy complications, stillbirth and neonatal death. Syphilis is under-diagnosed in pregnant women. Point-of-care rapid syphilis tests (RST) allow for same-day treatment and address logistical barriers to testing encountered with standard Rapid Plasma Reagin testing. Recent literature emphasises successful introduction of new health technologies requires healthcare worker (HCW) acceptance, effective training, quality monitoring and robust health systems. Following a successful pilot, the Zambian Ministry of Health (MoH) adopted RST into policy, integrating them into prevention of mother-to-child transmission of HIV clinics in four underserved Zambian districts. We compare HCW experiences, including challenges encountered in scaling up from a highly supported NGO-led pilot to a large-scale MoH-led national programme. Questionnaires were administered through structured interviews of 16 HCWs in two pilot districts and 24 HCWs in two different rollout districts. Supplementary data were gathered via stakeholder interviews, clinic registers and supervisory visits. Using a conceptual framework adapted from health technology literature, we explored RST acceptance and usability. Quantitative data were analysed using descriptive statistics. Key themes in qualitative data were explored using template analysis. Overall, HCWs accepted RST as learnable, suitable, effective tools to improve antenatal services, which were usable in diverse clinical settings. Changes in training, supervision and quality monitoring models between pilot and rollout may have influenced rollout HCW acceptance and compromised testing quality. While quality monitoring was integrated into national policy and training, implementation was limited during rollout despite financial support and mentorship. We illustrate that new health technology pilot research can rapidly translate into policy change and scale-up. However, training, supervision and quality assurance models should be reviewed and strengthened as rollout of the Zambian RST programme continues.

Introduction of Syphilis Point-of-Care Tests, from Pilot Study to National Programme Implementation in Zambia: A Qualitative Study of Healthcare Workers’ Perspectives on Testing, Training and Quality Assurance

PubMed Central

Ansbro, Éimhín M.; Gill, Michelle M.; Reynolds, Joanna; Shelley, Katharine D.; Strasser, Susan; Sripipatana, Tabitha; Ncube, Alexander Tshaka; Tembo Mumba, Grace; Terris-Prestholt, Fern; Peeling, Rosanna W.; Mabey, David

2015-01-01

Syphilis affects 1.4 million pregnant women globally each year. Maternal syphilis causes congenital syphilis in over half of affected pregnancies, leading to early foetal loss, pregnancy complications, stillbirth and neonatal death. Syphilis is under-diagnosed in pregnant women. Point-of-care rapid syphilis tests (RST) allow for same-day treatment and address logistical barriers to testing encountered with standard Rapid Plasma Reagin testing. Recent literature emphasises successful introduction of new health technologies requires healthcare worker (HCW) acceptance, effective training, quality monitoring and robust health systems. Following a successful pilot, the Zambian Ministry of Health (MoH) adopted RST into policy, integrating them into prevention of mother-to-child transmission of HIV clinics in four underserved Zambian districts. We compare HCW experiences, including challenges encountered in scaling up from a highly supported NGO-led pilot to a large-scale MoH-led national programme. Questionnaires were administered through structured interviews of 16 HCWs in two pilot districts and 24 HCWs in two different rollout districts. Supplementary data were gathered via stakeholder interviews, clinic registers and supervisory visits. Using a conceptual framework adapted from health technology literature, we explored RST acceptance and usability. Quantitative data were analysed using descriptive statistics. Key themes in qualitative data were explored using template analysis. Overall, HCWs accepted RST as learnable, suitable, effective tools to improve antenatal services, which were usable in diverse clinical settings. Changes in training, supervision and quality monitoring models between pilot and rollout may have influenced rollout HCW acceptance and compromised testing quality. While quality monitoring was integrated into national policy and training, implementation was limited during rollout despite financial support and mentorship. We illustrate that new health technology pilot research can rapidly translate into policy change and scale-up. However, training, supervision and quality assurance models should be reviewed and strengthened as rollout of the Zambian RST programme continues. PMID:26030741

Modelling of sedimentation and remobilization in in-line storage sewers for stormwater treatment.

PubMed

Frehmann, T; Flores, C; Luekewille, F; Mietzel, T; Spengler, B; Geiger, W F

2005-01-01

A special arrangement of combined sewer overflow tanks is the in-line storage sewer with downstream discharge (ISS-down). This layout has the advantage that, besides the sewer system, no other structures are required for stormwater treatment. The verification of the efficiency with respect to the processes of sedimentation and remobilization of sediment within the in-line storage sewer with downstream discharge is carried out in a combination of a field and a pilot plant study. The model study was carried out using a pilot plant model scaled 1:13. The following is intended to present some results of the pilot plant study and the mathematical empirical modelling of the sedimentation and remobilization process.

Pilot-scale studies on biological treatment of hypersaline wastewater at low temperature.

PubMed

Peng, Y Z; Zhu, G B; Wang, S Y; Yu, D S; Cui, Y W; Meng, X S

2005-01-01

In order to investigate the feasibility of biological treatment of hypersaline wastewater produced from toilet flushing with seawater at low temperature, pilot-scale studies were established with plug-flow activated sludge process at low temperature (5-9 degrees C) based on bench-scale experiments. The critical salinity concentration of 30 g/L, which resulted from the cooperation results of the non-halophilic bacteria and the halophilic bacteria, was drawn in bench-scale experiments. Pilot-scale studies showed that high COD removal efficiency, higher than 80%, was obtained at low temperature when 30 percent seawater was introduced. The salinity improved the settleability of activated sludge, and average sludge value dropped down from 38% to 22.5% after adding seawater. Seawater salinity had a strong negative effect on notronomonas and nitrobacter growth, but much more on the nitrobacter. The nitrification action was mainly accomplished by nitrosomonas. Bench-scale experiments using two SBRs were carried out for further investigation under different conditions of salinities, ammonia loadings and temperatures. Biological nitrogen removal via nitrite pathway from wastewater containing 30 percent seawater was achieved, but the ammonia removal efficiency was strongly related not only to the influent ammonia loading at different salinities but also to temperature. When the ratio of seawater to wastewater was 30 percent, and the ammonia loading was below the critical value of 0.15 kgNH4+-N/(kgMLSS.d), the ammonia removal efficiency via nitrite pathway was above 90%. The critical level of ammonia loading was 0.15, 0.08 and 0.03 kgNH4+-N/(kgMLSS.d) respectively at the different temperature 30 degrees C, 25 degrees C and 20 degrees C when the influent ammonia concentration was 60-80 mg/L and pH was 7.5-8.0.

Results of a Pilot-Scale Disinfection Test using Peracetic Acid (PAA) at the Oak Ridge National Laboratory (ORNL) Sewage Treatment Plant (STP)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Taylor, Paul Allen

The purpose of this report is to present the results of a small pilot-scale test using PAA to disinfect a side stream of the effluent from the ORNL STP. These results provide the basis for requesting approval for full-scale use of PAA at the ORNL STP.

Pilot-scale electrokinetic movement of HCB and Zn in real contaminated sediments enhanced with hydroxypropyl-beta-cyclodextrin.

PubMed

Li, Taiping; Yuan, Songhu; Wan, Jinzhong; Lin, Li; Long, Huayun; Wu, Xiaofeng; Lu, Xiaohua

2009-08-01

This study deals with the efficiency of a pilot-scale electrokinetic (EK) treatment on real aged sediments contaminated with hexachlorobenzene (HCB) and Zn. A total of 0.5m(3) of sediments were treated under a constant voltage in a polyvinyl chloride reactor. The changes of sediment pH, electrical conductivity (EC), organic content (OC), the transport of contaminants in sediments and the consumption of electric energy were evaluated. After 100 d processing, sediment pH slightly increased compared with the initial values, particularly in the bottom layer close to cathodic section, while sediment EC in most sections significantly decreased. Sediment OC in all sections increased, which implied that hydroxypropyl-beta-cyclodextrin (HPCD) was successfully penetrated across sediments by electroosmosis. Significant movement of contaminants was observed across sediments with negligible removals. Both HCB and Zn generally moved from sections near anode and accumulated near cathode. Upon the completion of treatment, the electric energy consumption was calculated as 563 kWhm(-3). This pilot-scale EK test indicates that it is difficult to achieve great removal of hydrophobic organic compounds (HOCs), or HOCs and heavy metal mixed contaminants, by EK treatment in large scale with the use of HPCD.

Laboratory, semi-pilot and room scale study of nitrite and molybdate mediated control of H(2)S emission from swine manure.

PubMed

Moreno, Lyman; Predicala, Bernardo; Nemati, Mehdi

2010-04-01

The effects of manure age on emission of H(2)S and required level of nitrite or molybdate to control these emissions were investigated in the present work. Molybdate mediated control of H(2)S emission was also studied in semi-pilot scale open systems, and in specifically designed chambers which simulated swine production rooms. With fresh 1-, 3- and 6-month old manures average H(2)S concentration in the headspace gas of the closed systems were 4856+/-460, 3431+/-208, 1037+/-98 ppm and non-detectable, respectively. Moreover, the level of nitrite or molybdate required to control the emission of H(2)S decreased as manure age increased. In the semi-pilot scale open system and chambers, average H(2)S concentration at the surface of agitated fresh manure were 831+/-26 and 88.4+/-5.7 ppm, respectively. Furthermore, 0.1-0.25 mM molybdate was sufficient to control the emission of H(2)S. A cost study for an average size swine operation showed that the cost of treatment with molybdate was less than 1% of the overall production cost for each market hog. Copyright 2009 Elsevier Ltd. All rights reserved.

Production of drinking water from raw water containing cyanobacteria--pilot plant studies for assessing the risk of microcystin breakthrough.

PubMed

Schmidt, Wido; Willmitzer, Hartmut; Bornmann, Katrin; Pietsch, Jörg

2002-01-01

Toxins in cyanobacteria are a recognized risk in the treatment of drinking-water treatment. Cyanotoxins can occur in two modifications: cell bound and dissolved in water. The process of toxin release may occur naturally, but it also may be induced through the processes of drinking-water treatment. Both causes of release are relevant to the safety of drinking water. This study investigated cyanotoxin release and elimination through different treatment trains in systematic pilot-scale studies with water from the Weida Reservoir, in Thuringia, Germany. The Weida Reservoir is a dimictic mesoeutrophic reservoir typical for a number of mountainous areas in Europe, with Planktothrix rubescens as the dominant phytoplankton species, and shows a characteristic seasonal pattern of population development and microcystin occurrence. To assess the risk of microcystin breakthrough, the pilot-scale results as well as results of laboratory-scale experiments were used for developing a kinetic model of toxin release in relation to elimination. By calculating removal efficiency of total microcystins (cell bound and dissolved) for different treatment trains, raw water quality was related to the quality targets for finished water, and breakthrough risks could be calculated for given treatment trains and varying cyanobacterial population densities in the reservoir. Copyright 2002 Wiley Periodicals, Inc.

Pilot study of a targeted dance class for physical rehabilitation in children with cerebral palsy

PubMed Central

López-Ortiz, Citlali; Egan, Tara; Gaebler-Spira, Deborah J

2016-01-01

Introduction: This pilot study evaluates the effects of a targeted dance class utilizing classical ballet principles for rehabilitation of children with cerebral palsy on balance and upper extremity control. Methods: Twelve children with cerebral palsy (ages 7–15 years) with Gross Motor Function Classification scores II–IV participated in this study and were assigned to either a control group or targeted dance class group. Targeted dance class group participated in 1-h classes three times per week in a 4-week period. The Pediatric Balance Scale and the Quality of Upper Extremity Skills Test were administered before, after, and 1 month after the targeted dance class. Results: Improvements in the Pediatric Balance Scale were present in the targeted dance class group in before versus after and before versus 1 month follow-up comparisons (p-value = 0.0088 and p-value = 0.019, respectively). The Pediatric Balance Scale changes were not significant in the control group. The Quality of Upper Extremity Skills Test did not reach statistical differences in either group. Conclusion: Classical ballet as an art form involves physical training, musical accompaniment, social interactions, and emotional expression that could serve as adjunct to traditional physical therapy. This pilot study demonstrated improvements in balance control. A larger study with a more homogeneous sample is warranted. PMID:27721977

Removals of cryptosporidium parvum oocysts and cryptosporidium-sized polystyrene microspheres from swimming pool water by diatomaceous earth filtration and perlite-sand filtration.

PubMed

Lu, Ping; Amburgey, James E; Hill, Vincent R; Murphy, Jennifer L; Schneeberger, Chandra L; Arrowood, Michael J; Yuan, Tao

2017-06-01

Removal of Cryptosporidium-sized microspheres and Cryptosporidium parvum oocysts from swimming pools was investigated using diatomaceous earth (DE) precoat filtration and perlite-sand filtration. In pilot-scale experiments, microsphere removals of up to 2 log were obtained with 0.7 kg·DE/m 2 at a filtration rate of 5 m/h. A slightly higher microsphere removal (2.3 log) was obtained for these DE-precoated filters when the filtration rate was 3.6 m/h. Additionally, pilot-scale perlite-sand filters achieved greater than 2 log removal when at least 0.37 kg/m 2 of perlite was used compared to 0.1-0.4 log removal without perlite both at a surface loading rate of 37 m/h. Full-scale testing achieved 2.7 log of microspheres and oocysts removal when 0.7 kg·DE/m 2 was used at 3.6 m/h. Removals were significantly decreased by a 15-minute interruption of the flow (without any mechanical agitation) to the DE filter in pilot-scale studies, which was not observed in full-scale filters. Microsphere removals were 2.7 log by perlite-sand filtration in a full-scale swimming pool filter operated at 34 m/h with 0.5 kg/m 2 of perlite. The results demonstrate that either a DE precoat filter or a perlite-sand filter can improve the efficiency of removal of microspheres and oocysts from swimming pools over a standard sand filter under the conditions studied.

Developing Scale for Determining the Social Participation Skills for Children and Analyzing Its Psychometric Characteristics

ERIC Educational Resources Information Center

Samanci, Osman; Ocakci, Ebru; Seçer, Ismail

2018-01-01

The purpose of this research is to conduct validity and reliability studies of the Scale for the Determining Social Participation for Children, developed to measure social participation skills of children aged 7-10 years. During the development of the scale, pilot schemes, validity analyzes, and reliability analyzes were conducted. In this…

REBURNING THERMAL AND CHEMICAL PROCESSES IN A TWO-DIMENSIONAL PILOT-SCALE SYSTEM

EPA Science Inventory

The paper describes an experimental investigation of the thermal and chemical processes influencing NOx reduction by natural gas reburning in a two-dimensional pilot-scale combustion system. Reburning effectiveness for initial NOx levels of 50-500 ppm and reburn stoichiometric ra...

Thermochemical Users Facility | Bioenergy | NREL

Science.gov Websites

collaborate on research and development efforts or to use our equipment to test their materials and processes NREL's thermochemical process integration, scale-up, and piloting research. Schematic diagram of NRELs about NREL's thermochemical process integration, scale-up, and piloting research. Thermochemical

NOX REMOVAL WITH COMBINED SELECTIVE CATALYTIC REDUCTION AND SELECTIVE NONCATALYTIC REDUCTION: PILOT- SCALE TEST RESULTS

EPA Science Inventory

Pilot-scale tests were conducted to develop a combined nitrogen oxide (NOx) reduction technology using both selective catalytic reduction (SCR) and selective noncatalytic reduction (SNCR). A commercially available vanadium-and titatnium-based composite honeycomb catalyst and enh...

A pilot study of mercury liberation and capture from coal-fired power plant fly ash.

PubMed

Li, Jin; Gao, Xiaobing; Goeckner, Bryna; Kollakowsky, Dave; Ramme, Bruce

2005-03-01

The coal-fired electric utility generation industry has been identified as the largest anthropogenic source of mercury (Hg) emissions in the United States. One of the promising techniques for Hg removal from flue gas is activated carbon injection (ACI). The aim of this project was to liberate Hg bound to fly ash and activated carbon after ACI and provide high-quality coal combustion products for use in construction materials. Both bench- and pilot-scale tests were conducted to liberate Hg using a thermal desorption process. The results indicated that up to 90% of the Hg could be liberated from the fly ash or fly-ash-and-activated-carbon mixture using a pilot-scale apparatus (air slide) at 538 degrees C with a very short retention time (less than 1 min). Scanning electron microscope (SEM) evaluation indicated no significant change in fly ash carbon particle morphology following the thermal treatment. Fly ash particles collected in the baghouse of the pilot-scale apparatus were smaller in size than those collected at the exit of the air slide. A similar trend was observed in carbon particles separated from the fly ash using froth flotation. The results of this study suggest a means for power plants to reduce the level of Hg in coal-combustion products and potentially recycle activated carbon while maintaining the resale value of fly ash. This technology is in the process of being patented.

Manufacturing demonstration of microbially mediated zinc sulfide nanoparticles in pilot-plant scale reactors.

PubMed

Moon, Ji-Won; Phelps, Tommy J; Fitzgerald, Curtis L; Lind, Randall F; Elkins, James G; Jang, Gyoung Gug; Joshi, Pooran C; Kidder, Michelle; Armstrong, Beth L; Watkins, Thomas R; Ivanov, Ilia N; Graham, David E

2016-09-01

The thermophilic anaerobic metal-reducing bacterium Thermoanaerobacter sp. X513 efficiently produces zinc sulfide (ZnS) nanoparticles (NPs) in laboratory-scale (≤ 24-L) reactors. To determine whether this process can be up-scaled and adapted for pilot-plant production while maintaining NP yield and quality, a series of pilot-plant scale experiments were performed using 100-L and 900-L reactors. Pasteurization and N2-sparging replaced autoclaving and boiling for deoxygenating media in the transition from small-scale to pilot plant reactors. Consecutive 100-L batches using new or recycled media produced ZnS NPs with highly reproducible ~2-nm average crystallite size (ACS) and yields of ~0.5 g L(-1), similar to the small-scale batches. The 900-L pilot plant reactor produced ~320 g ZnS without process optimization or replacement of used medium; this quantity would be sufficient to form a ZnS thin film with ~120 nm thickness over 0.5 m width × 13 km length. At all scales, the bacteria produced significant amounts of acetic, lactic, and formic acids, which could be neutralized by the controlled addition of sodium hydroxide without the use of an organic pH buffer, eliminating 98 % of the buffer chemical costs. The final NP products were characterized using XRD, ICP-OES, TEM, FTIR, PL, DLS, HPLC, and C/N analyses, which confirmed that the growth medium without organic buffer enhanced the ZnS NP properties by reducing carbon and nitrogen surface coatings and supporting better dispersivity with similar ACS.

Design of pilot studies to inform the construction of composite outcome measures.

PubMed

Edland, Steven D; Ard, M Colin; Li, Weiwei; Jiang, Lingjing

2017-06-01

Composite scales have recently been proposed as outcome measures for clinical trials. For example, the Prodromal Alzheimer's Cognitive Composite (PACC) is the sum of z-score normed component measures assessing episodic memory, timed executive function, and global cognition. Alternative methods of calculating composite total scores using the weighted sum of the component measures that maximize signal-to-noise of the resulting composite score have been proposed. Optimal weights can be estimated from pilot data, but it is an open question how large a pilot trial is required to calculate reliably optimal weights. In this manuscript, we describe the calculation of optimal weights, and use large-scale computer simulations to investigate the question of how large a pilot study sample is required to inform the calculation of optimal weights. The simulations are informed by the pattern of decline observed in cognitively normal subjects enrolled in the Alzheimer's Disease Cooperative Study (ADCS) Prevention Instrument cohort study, restricting to n=75 subjects age 75 and over with an ApoE E4 risk allele and therefore likely to have an underlying Alzheimer neurodegenerative process. In the context of secondary prevention trials in Alzheimer's disease, and using the components of the PACC, we found that pilot studies as small as 100 are sufficient to meaningfully inform weighting parameters. Regardless of the pilot study sample size used to inform weights, the optimally weighted PACC consistently outperformed the standard PACC in terms of statistical power to detect treatment effects in a clinical trial. Pilot studies of size 300 produced weights that achieved near-optimal statistical power, and reduced required sample size relative to the standard PACC by more than half. These simulations suggest that modestly sized pilot studies, comparable to that of a phase 2 clinical trial, are sufficient to inform the construction of composite outcome measures. Although these findings apply only to the PACC in the context of prodromal AD, the observation that weights only have to approximate the optimal weights to achieve near-optimal performance should generalize. Performing a pilot study or phase 2 trial to inform the weighting of proposed composite outcome measures is highly cost-effective. The net effect of more efficient outcome measures is that smaller trials will be required to test novel treatments. Alternatively, second generation trials can use prior clinical trial data to inform weighting, so that greater efficiency can be achieved as we move forward.

Laboratory and pilot-scale bioremediation of pentaerythritol tetranitrate (PETN) contaminated soil.

PubMed

Zhuang, Li; Gui, Lai; Gillham, Robert W; Landis, Richard C

2014-01-15

PETN (pentaerythritol tetranitrate), a munitions constituent, is commonly encountered in munitions-contaminated soils, and pose a serious threat to aquatic organisms. This study investigated anaerobic remediation of PETN-contaminated soil at a site near Denver Colorado. Both granular iron and organic carbon amendments were used in both laboratory and pilot-scale tests. The laboratory results showed that, with various organic carbon amendments, PETN at initial concentrations of between 4500 and 5000mg/kg was effectively removed within 84 days. In the field trial, after a test period of 446 days, PETN mass removal of up to 53,071mg/kg of PETN (80%) was achieved with an organic carbon amendment (DARAMEND) of 4% by weight. In previous laboratory studies, granular iron has shown to be highly effective in degrading PETN. However, for both the laboratory and pilot-scale tests, granular iron was proven to be ineffective. This was a consequence of passivation of the iron surfaces caused by the very high concentrations of nitrate in the contaminated soil. This study indicated that low concentration of organic carbon was a key factor limiting bioremediation of PETN in the contaminated soil. Furthermore, the addition of organic carbon amendments such as the DARAMEND materials or brewers grain, proved to be highly effective in stimulating the biodegradation of PETN and could provide the basis for full-scale remediation of PETN-contaminated sites. Copyright © 2013 Elsevier B.V. All rights reserved.

A pilot study for determining the optimal operation condition for simultaneously controlling the emissions of PCDD/Fs and PAHs from the iron ore sintering process.

PubMed

Chen, Yu-Cheng; Tsai, Perng-Jy; Mou, Jin-Luh; Kuo, Yu-Chieh; Wang, Shih-Min; Young, Li-Hao; Wang, Ya-Fen

2012-09-01

In this study, the cost-benefit analysis technique was developed and incorporated into the Taguchi experimental design to determine the optimal operation combination for the purpose of providing a technique solution for controlling both emissions of PCDD/Fs and PAHs, and increasing both the sinter productivity (SP) and sinter strength (SS) simultaneously. Four operating parameters, including the water content, suction pressure, bed height, and type of hearth layer, were selected and all experimental campaigns were conducted on a pilot-scale sinter pot to simulate various sintering operating conditions of a real-scale sinter plant. The resultant optimal combination could reduce the total carcinogenic emissions arising from both emissions of PCDD/Fs and PAHs by 49.8%, and increase the sinter benefit associated with the increase in both SP and SS by 10.1%, as in comparison with the operation condition currently used in the real plant. The ANOVA results indicate that the suction pressure was the most dominant parameter in determining the optimal operation combination. The above result was theoretically plausible since the higher suction pressure provided more oxygen contents leading to the decrease in both PCDD/F and PAH emissions. But it should be noted that the results obtained from the present study were based on pilot scale experiments, conducting confirmation tests in a real scale plant are still necessary in the future. Copyright © 2012 Elsevier Ltd. All rights reserved.

Assessment of dyspnoea in the emergency department by numeric and visual scales: A pilot study.

PubMed

Placido, Rui; Gigaud, Carine; Gayat, Etienne; Ferry, Axelle; Cohen-Solal, Alain; Plaisance, Patrick; Mebazaa, Alexandre; Laribi, Said

2015-04-01

Dyspnoea is a common and often debilitating symptom that affects up to 50% of patients admitted to acute tertiary care hospitals. The primary purpose of this study was to compare the numeric rating scale (NRS) and the visual analogue scale (VAS) for dyspnoea evaluation in the ED setting. This was a cohort study of patients admitted to the ED in a university hospital, with dyspnoea as the chief complaint. The agreement of the two dyspnoea scales was assessed using the intraclass correlation coefficient (ICC). One hundred and seventeen patients were included in this analysis. The median age for the whole study population was 67 years and 42% of patients were male. The aetiology of dyspnoea was acute heart failure (AHF) in 35% of patients. There was good agreement between the two scores (ICC=0.795; 95% CI=0.717-0.853; P<0.001). This pilot study demonstrated that numerical rating and visual analogue scales agree well when assessing the severity of dyspnoea in the ED. Further studies with larger cohorts of patients are needed to confirm these preliminary results. Copyright © 2015 Société française d’anesthésie et de réanimation (Sfar). All rights reserved.

Instrument Development of Integrative Health and Wellness Assessment™.

PubMed

McElligott, Deborah; Eckardt, Sarah; Montgomery Dossey, Barbara; Luck, Susan; Eckardt, Patricia

2017-12-01

The nurse coach role was developed to address the needs of our nation and the world for health and wellbeing. The Theory of Integrative Nurse Coaching provides a foundation for coaching interventions supporting health promotion, and a framework for the development of the Integrative Health and Wellness Assessment (IHWA) short form. This 36-question Likert-type scale self-reporting tool assists participants in assessing healthy behaviors through a self-reflection process, provides information for the coaching relationship, and may be an outcome measurement. This article describes the history of the IHWA tool and the development and pilot testing of the IHWA short form using guidelines provided by DeVellis. Results of the Kaiser-Meyer-Olkin test yielded a value of .520, and the Bartlett's test of sphericity was significant. Cronbach's alpha overall scale internal consistency was .88 ( n = 36). Pilot study results indicate that the scale could be improved through additional revision, and an ongoing study is in progress.

ClearFuels-Rentech Integrated Biorefinery Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pearson, Joshua

The project Final Report describes the validation of the performance of the integration of two technologies that were proven individually on a pilot scale and were demonstrated as a pilot scale integrated biorefinery. The integrated technologies were a larger scale ClearFuels’ (CF) advanced flexible biomass to syngas thermochemical high efficiency hydrothermal reformer (HEHTR) technology with Rentech’s (RTK) existing synthetic gas to liquids (GTL) technology.

Tagging and Playback Studies to Toothed Whales

DTIC Science & Technology

2012-09-30

More playbacks of sonar have been conducted to pilot whales (Globicephala sp.), which are large pelagic delphinids, than to any other genus of cetacean...the group across different spatial scales. In particular, results showing how pilot whales use repeated, stereotyped calls (Sayigh et al. 2012) to re...establish contact with their social group following separations may prove valuable for testing whether monitoring for stereotyped calls might

Transition to Glass: Pilot Training for High-Technology Transport Aircraft

DTIC Science & Technology

1999-05-01

training programs D. Training considerations STUDY METHODOLOGY A. Basic questions and premises B. Questionnaires: attitude scales, demography , and flying...product of many tributaries, including the original Continental ("Old Continental" as it is called by pilots), Pioneer , Texas International, Frontier...to the southwest and later Hawaii. In 1953 Continental acquired Pioneer Airlines, with 16 destinations in the west. Six moved the company from El

REMOVAL OF PCBS FROM A CONTAMINATED SOIL USING CF-SYSTEMS SOLVENT EXTRACTION PROCESS

EPA Science Inventory

The US EPA's START team in cooperation with EPA's SITE program evaluated a pilot scale solvent extraction process developed by CF-Systems. This process uses liquified propane to extract organic contaminants from soils, sludges, and sediments. A pilot-scale evaluation was conducte...

FATE OF SEX HORMONES IN TWO PILOT-SCALE MUNICIPAL WASTEWATER TREATMENT PLANTS: CONVENTIONAL TREATMENT

EPA Science Inventory

The fate of seven sex hormones (estrone (E1), estradiol (E2), estriol (E3), ethinylestradiol (EE2), testosterone, androstenedione, and progesterone) was determined in two pilot-scale wastewater treatment plants operated under conventional loading conditions. The levels of hormon...

Sleep debt and depression in female college students.

PubMed

Regestein, Quentin; Natarajan, Viji; Pavlova, Milena; Kawasaki, Susan; Gleason, Ray; Koff, Elissa

2010-03-30

The objective of the study was to evaluate relationships between sleep habits and depressive symptoms. Pilot study data were collected about sleep schedules, related factors and depression in female college students to find whether their sleep schedules correlate with affective symptoms. In the subsequent main study, similar information was collected under more controlled conditions. Depression was measured using the CES-D (Center for Epidemiologic Studies Depression Scale) and HAM-D-3 (modified Hamilton Depression Rating Scale). Response rates were 31.3% of eligible students for the pilot survey and 71.6% for the main study. Both studies showed that about 20% of students reported weekday sleep debts of greater than 2 h and about 28% reported significantly greater sleep debt and had significantly higher depression scores (P<0.0001) than other students. Melancholic symptoms indicated by high CES-D scores (>24), were observed in 24% of students. Sleep problems explained 13% of the variance for both the CESD scale and the HAM-D-3 scale. Among female college students, those who report a sleep debt of at least 2 h or significant daytime sleepiness have a higher risk of reporting melancholic symptoms than others. Copyright 2008 Elsevier Ltd. All rights reserved.

Validation and Exploration of Instruments for Assessing Public Knowledge of and Attitudes toward Nanotechnology

ERIC Educational Resources Information Center

Lin, Shu-Fen; Lin, Huann-shyang; Wu, Yi-ying

2013-01-01

The purposes of this study were to develop instruments that assess public knowledge of nanotechnology (PKNT), public attitudes toward nanotechnology (PANT) and conduct a pilot study for exploring the relationship between PKNT and PANT. The PKNT test was composed of six scales involving major nanotechnology concepts, including size and scale,…

AN INTERDISCIPLINARY APPROACH TO ADDRESSING NEIGHBORHOOD SCALE AIR QUALITY CONCERNS: THE INTEGRATION OF GIS, URBAN MORPHOLOGY, PREDICTIVE METEOROLOGY, AND AIR QUALITY MONITORING TOOLS

EPA Science Inventory

The paper describes a project that combines the capabilities of urban geography, raster-based GIS, predictive meteorological and air pollutant diffusion modeling, to support a neighborhood-scale air quality monitoring pilot study under the U.S. EPA EMPACT Program. The study ha...

The Psychometric Properties of the Difficult Behavior Self-Efficacy Scale

ERIC Educational Resources Information Center

Oh, Hyun-Kyoung; Kozub, Francis M.

2010-01-01

The study was designed to estimate the psychometric properties of Hastings and Brown's (2002a) Difficult Behavior Self-efficacy Scale. Participants were two samples of physical educators teaching in Korea (n = 229) and the United States (U.S.; n = 139). An initial translation of the questionnaire to Korean and pilot study were conducted along with…

Discrimination of surface wear on obsidian tools using LSCM and RelA: pilot study results (area-scale analysis of obsidian tool surfaces).

PubMed

Stemp, W James; Chung, Steven

2011-01-01

This pilot study tests the reliability of laser scanning confocal microscopy (LSCM) to quantitatively measure wear on experimental obsidian tools. To our knowledge, this is the first use of confocal microscopy to study wear on stone flakes made from an amorphous silicate like obsidian. Three-dimensional surface roughness or texture area scans on three obsidian flakes used on different contact materials (hide, shell, wood) were documented using the LSCM to determine whether the worn surfaces could be discriminated using area-scale analysis, specifically relative area (RelA). When coupled with the F-test, this scale-sensitive fractal analysis could not only discriminate the used from unused surfaces on individual tools, but was also capable of discriminating the wear histories of tools used on different contact materials. Results indicate that such discriminations occur at different scales. Confidence levels for the discriminations at different scales were established using the F-test (mean square ratios or MSRs). In instances where discrimination of surface roughness or texture was not possible above the established confidence level based on MSRs, photomicrographs and RelA assisted in hypothesizing why this was so. Copyright © 2011 Wiley Periodicals, Inc.

Catalytic thermal cracking of postconsumer waste plastics to fuels. 2. Pilot-scale thermochemical conversion

USDA-ARS?s Scientific Manuscript database

Synthetic gasoline and diesel fuels were prepared via catalytic and noncatalytic pyrolysis of waste polyethylene and polypropylene plastics followed by distillation of plastic crude oils. Reaction conditions optimized using a 2 L batch reactor were applied to pilot-scale production of plastic crude ...

A pilot scale electrical infrared dry-peeling system for tomatoes: design and performance evaluation

USDA-ARS?s Scientific Manuscript database

A pilot scale infrared dry-peeling system for tomatoes was designed and constructed. The system consisted of three major sections including the IR heating, vacuum, and pinch roller sections. The peeling performance of the system was examined under different operational conditions using tomatoes with...

Pilot-scale fractionation of whey proteins with supercritical CO2

USDA-ARS?s Scientific Manuscript database

A new pilot-scale process is being developed and optimized for the separation of whey proteins into two enriched, highly functional fractions that are free of contaminants. The fractionation of whey protein isolate (WPI), which contains approximately 32% alpha-lactalbumin (alpha-LA) and 61% beta-lac...

Short-Term Operations Plan for Collection of Bulk Quantity CBP Liquid in Support of a Pilot-Scale Treatabilty Evaluation with Water Recovery Inc

EPA Pesticide Factsheets

June 3, 2011 work plan for a pilot-scale treatability evaluation with a commercial wastewater treatment facility, Water Recovery Inc. (WRI) located in Jacksonville, Florida. Region ID: 04 DocID: 10749927, DocDate: 06-03-2011

SHIRCO PILOT-SCALE INFRARED INCINERATION SYSTEM AT THE ROSE TOWNSHIP DEMODE ROAD SUPERFUND SITE

EPA Science Inventory

Under the Superfund Innovative Technology Evaluation or SITE Program, an evaluation was made of the Shirco Pilot-Scale Infrared Incineration System during 17 separate test runs under varying operating conditions. The tests were conducted at the Demode Road Superfund site in Ros...

Final report from VFL Technologies for the pilot-scale thermal treatment of lower East Fork Poplar Creek floodplain soils. LEFPC appendices, Volume 4, Appendix V-C

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1994-09-01

This is the the final verification run data package for pilot scale thermal treatment of lower East Fork Poplar Creek floodplain soils. Included are data on volatiles, semivolatiles, and TCLP volatiles.

PILOT-SCALE DEMONSTRATION OF A SLURRY-PHASE BIOLOGICAL REACTOR FOR CREOSOTE-CONTAMINATED SOIL - APPLICATION ANALYSIS REPORT

EPA Science Inventory

In support of the U.S. Environmental Protection Agency’s (EPA) Superfund Innovative Technology Evaluation (SITE) Program, a pilot-scale demonstration of a slurry-phase bioremediation process was performed May 1991 at the EPA’s Test & Evaluation Facility in Cincinnati, OH. In this...

DETERMINATION OF SEX HORMONES AND NONYLPHENOL ETHOXYLATES IN THE AQUEOUS MATRIXES OF TWO PILOT-SCALE MUNICIPAL WASTEWATER TREATMENT PLANTS

EPA Science Inventory

Two analytical methods were developed and refined for the detection and quantitation of two groups of endocrine-disrupting chemicals (EDCs) in the liquid matrixes of two pilot-scale municipal wastewater treatment plants. The targeted compounds are seven sex hormones (estradiol, ...

Nitrous oxide emissions from one-step partial nitritation/anammox processes.

PubMed

Yang, Jingjing; Trela, Jozef; Plaza, Elzbieta

2016-12-01

Measurements of nitrous oxide were made at pilot- and full-scale plants to evaluate greenhouse gas emissions from one-step partial nitritation/anammox processes applied in moving bed biofilm reactors treating reject water. It was found that 0.51-1.29% and 0.35-1.33% of the total nitrogen loads in the pilot- and full-scale reactor, respectively, were emitted as nitrous oxide. Between 80 and 90% of nitrous oxide emissions were in gaseous form and the rest amount was found in the reactor effluent; over 90% of nitrous oxide emissions occurred in the aerated period and less than 8% in the non-aerated period in the full-scale study. Nitrous oxide productions/consumptions were closely related to aeration and the nitrogen loads applied in the system.

Effects of a Mindfulness Group on Latino Adolescent Students: Examining Levels of Perceived Stress, Mindfulness, Self-Compassion, and Psychological Symptoms

ERIC Educational Resources Information Center

Edwards, Michelle; Adams, Eve M.; Waldo, Michael; Hadfield, O. D.; Biegel, Gina M.

2014-01-01

This pilot study evaluated the impact of mindfulness groups on 20 Latino middle school students who participated in 8-session structured groups using the Mindfulness-Based Stress Reduction for Teens curriculum. The participants' scores on the Mindful Attention Awareness Scale; the Self-Compassion Scale; the Perceived Stress Scale; and the…

A SCALE-UP Mock-Up: Comparison of Student Learning Gains in High- and Low-Tech Active-Learning Environments

ERIC Educational Resources Information Center

Soneral, Paula A. G.; Wyse, Sara A.

2017-01-01

Student-centered learning environments with upside-down pedagogies (SCALE-UP) are widely implemented at institutions across the country, and learning gains from these classrooms have been well documented. This study investigates the specific design feature(s) of the SCALE-UP classroom most conducive to teaching and learning. Using pilot survey…

Grid-Enabled Quantitative Analysis of Breast Cancer

DTIC Science & Technology

2009-10-01

large-scale, multi-modality computerized image analysis . The central hypothesis of this research is that large-scale image analysis for breast cancer...pilot study to utilize large scale parallel Grid computing to harness the nationwide cluster infrastructure for optimization of medical image ... analysis parameters. Additionally, we investigated the use of cutting edge dataanalysis/ mining techniques as applied to Ultrasound, FFDM, and DCE-MRI Breast

Characterization of reactive CaCO 3 crystallization in a fluidized bed reactor as a central process of direct air capture

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burhenne, Luisa; Giacomin, Caroline; Follett, Trevor

A laboratory-scale, fluidized-bed pellet reactor (BPR) was used to investigate a CaCO 3 crystallization process for the recovery of CO 2 in a Direct Air Capture (DAC) process. The BPR performance was validated against data from a pilot-scale unit. Subsequently, the pellet growth under process-relevant conditions was studied over a period of 144 h. The experimental results with the BPR, containing a bed of pellets sized between 0.65 and 0.84 mm, have shown that a calcium retention of 80% can be achieved at a fluidization velocity of 60 m h -1 and a calcium loading rate of 3 mol hmore » -1. This result is consistent with calcium retention observed at pilot scale operation and hence, results from the BPR are considered representative for the pilot scale unit. Starting with a bed of pellets sized between 0.15 and 0.5 mm, the average pellet growth rate, G, at the reactor bottom increased from 8.1E-10 to 11E–10 m s -1 at the onset and decreased to 4.9E–10 m s -1 over the course of a 144 h test. The calcium retention over the course the test showed the same trend (initial increase and final decrease) as the pellet growth rate. A theoretical bed growth model was developed and validated against data from the pilot scale and benchtop pellet reactors. The model was used to calculate the bed porosity and total pellet surface area in each control volume. Lastly, the pellet surface area growth at the bottom of the reactor reproduced the pellet growth and retention data trends.« less

Characterization of reactive CaCO 3 crystallization in a fluidized bed reactor as a central process of direct air capture

DOE PAGES

Burhenne, Luisa; Giacomin, Caroline; Follett, Trevor; ...

2017-10-25

A laboratory-scale, fluidized-bed pellet reactor (BPR) was used to investigate a CaCO 3 crystallization process for the recovery of CO 2 in a Direct Air Capture (DAC) process. The BPR performance was validated against data from a pilot-scale unit. Subsequently, the pellet growth under process-relevant conditions was studied over a period of 144 h. The experimental results with the BPR, containing a bed of pellets sized between 0.65 and 0.84 mm, have shown that a calcium retention of 80% can be achieved at a fluidization velocity of 60 m h -1 and a calcium loading rate of 3 mol hmore » -1. This result is consistent with calcium retention observed at pilot scale operation and hence, results from the BPR are considered representative for the pilot scale unit. Starting with a bed of pellets sized between 0.15 and 0.5 mm, the average pellet growth rate, G, at the reactor bottom increased from 8.1E-10 to 11E–10 m s -1 at the onset and decreased to 4.9E–10 m s -1 over the course of a 144 h test. The calcium retention over the course the test showed the same trend (initial increase and final decrease) as the pellet growth rate. A theoretical bed growth model was developed and validated against data from the pilot scale and benchtop pellet reactors. The model was used to calculate the bed porosity and total pellet surface area in each control volume. Lastly, the pellet surface area growth at the bottom of the reactor reproduced the pellet growth and retention data trends.« less

Physical-chemical treatment of rainwater runoff in recovery and recycling companies: Pilot-scale optimization.

PubMed

Blondeel, Evelyne; Depuydt, Veerle; Cornelis, Jasper; Chys, Michael; Verliefde, Arne; Van Hulle, Stijin Wim Henk

2015-01-01

Pilot-scale optimisation of different possible physical-chemical water treatment techniques was performed on the wastewater originating from three different recovery and recycling companies in order to select a (combination of) technique(s) for further full-scale implementation. This implementation is necessary to reduce the concentration of both common pollutants (such as COD, nutrients and suspended solids) and potentially toxic metals, polyaromatic hydrocarbons and poly-chlorinated biphenyls frequently below the discharge limits. The pilot-scale tests (at 250 L h(-1) scale) demonstrate that sand anthracite filtration or coagulation/flocculation are interesting as first treatment techniques with removal efficiencies of about 19% to 66% (sand anthracite filtration), respectively 18% to 60% (coagulation/flocculation) for the above mentioned pollutants (metals, polyaromatic hydrocarbons and poly chlorinated biphenyls). If a second treatment step is required, the implementation of an activated carbon filter is recommended (about 46% to 86% additional removal is obtained).

The effects of workload on respiratory variables in simulated flight: a preliminary study.

PubMed

Karavidas, Maria Katsamanis; Lehrer, Paul M; Lu, Shou-En; Vaschillo, Evgeny; Vaschillo, Bronya; Cheng, Andrew

2010-04-01

In this pilot study, we investigated respiratory activity and end-tidal carbon dioxide (P(et)CO(2)) during exposure to varying levels of work load in a simulated flight environment. Seven pilots (age: 34-60) participated in a one-session test on the Boeing 737-800 simulator. Physiological data were collected while pilots wore an ambulatory multi-channel recording device. Respiratory variables, including inductance plethysmography (respiratory pattern) and pressure of end-tidal carbon dioxide (P(et)CO(2)), were collected demonstrating change in CO(2) levels proportional to changes in flight task workload. Pilots performed a set of simulation flight tasks. Pilot performance was rated for each task by a test pilot; and self-report of workload was taken using the NASA-TLX scale. Mixed model analysis revealed that respiration rate and minute ventilation are significantly associated with workload levels and evaluator scores controlling for "vanilla baseline" condition. Hypocapnia exclusively occurred in tasks where pilots performed more poorly. This study was designed as a preliminary investigation in order to develop a psychophysiological assessment methodology, rather than to offer conclusive findings. The results show that the respiratory system is very reactive to high workload conditions in aviation and suggest that hypocapnia may pose a flight safety risk under some circumstances. Copyright © 2010 Elsevier B.V. All rights reserved.

Measuring Pilot Knowledge in Training: The Pathfinder Network Scaling Technique

DTIC Science & Technology

2007-01-01

Network Scaling Technique Leah J. Rowe Roger W. Schvaneveldt L -3 Communications Arizona State University Mesa, AZ Mesa, AZ leah.rowe...7293 Page 2 of 8 Measuring Pilot Knowledge in Training: The Pathfinder Network Scaling Technique Leah J. Rowe Roger W. Schvaneveldt L -3...training. ABOUT THE AUTHORS Leah J. Rowe is a Training Research Specialist with L -3 Communications at the Air Force Research Laboratory

EVALUATION OF SCR CATALYSTS FOR COMBINED CONTROL OF NOX AND MERCURY

EPA Science Inventory

The report documents two-task, bench- and pilot-scale research on the effect of selective catalytic reduction (SCR) catalysts on mercury speciation in Illinois and Powder River Basin (PRB) coal combustion flue gases. In task I, a bench-scale reactor was used to study the oxidatio...

The effects of different dry roast parameters on peanut quality using an industrial, belt-type roaster simulator

USDA-ARS?s Scientific Manuscript database

Recent lab scale experiments demonstrated that peanuts roasted to equivalent surface colors at different temperature/time combinations can vary substantially in chemical and physical properties related to product quality. This study expanded that approach to a pilot plant scale roaster that simulate...

Chronic care coordination by integrating care through a team-based, population-driven approach: a case study.

PubMed

van Eeghen, Constance O; Littenberg, Benjamin; Kessler, Rodger

2018-05-23

Patients with chronic conditions frequently experience behavioral comorbidities to which primary care cannot easily respond. This study observed a Vermont family medicine practice with integrated medical and behavioral health services that use a structured approach to implement a chronic care management system with Lean. The practice chose to pilot a population-based approach to improve outcomes for patients with poorly controlled Type 2 diabetes using a stepped-care model with an interprofessional team including a community health nurse. This case study observed the team's use of Lean, with which it designed and piloted a clinical algorithm composed of patient self-assessment, endorsement of behavioral goals, shared documentation of goals and plans, and follow-up. The team redesigned workflows and measured reach (patients who engaged to the end of the pilot), outcomes (HbA1c results), and process (days between HbA1c tests). The researchers evaluated practice member self-reports about the use of Lean and facilitators and barriers to move from pilot to larger scale applications. Of 20 eligible patients recruited over 3 months, 10 agreed to participate and 9 engaged fully (45%); 106 patients were controls. Relative to controls, outcomes and process measures improved but lacked significance. Practice members identified barriers that prevented implementation of all changes needed but were in agreement that the pilot produced useful outcomes. A systematized, population-based, chronic care management service is feasible in a busy primary care practice. To test at scale, practice leadership will need to allocate staffing, invest in shared documentation, and standardize workflows to streamline office practice responsibilities.

The Characterization of Grade PCEA Recycle Graphite Pilot Scale Billets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burchell, Timothy D; Pappano, Peter J

2010-10-01

Here we report the physical properties of a series specimens machined from pilot scale (~ 152 mm diameter x ~305 mm length) grade PCEA recycle billets manufactured by GrafTech. The pilot scale billets were processed with increasing amounts of (unirradiated) graphite (from 20% to 100%) introduced to the formulation with the goal of determining if large fractions of recycle graphite have a deleterious effect on properties. The properties determined include Bulk Density, Electrical Resistivity, Elastic (Young s) Modulus, and Coefficient of Thermal Expansion. Although property variations were observed to be correlated with the recycle fraction, the magnitude of the variationsmore » was noted to be small.« less

Application of simultaneous saccharification and fermentation (SSF) from viscosity reducing of raw sweet potato for bioethanol production at laboratory, pilot and industrial scales.

PubMed

Zhang, Liang; Zhao, Hai; Gan, Mingzhe; Jin, Yanlin; Gao, Xiaofeng; Chen, Qian; Guan, Jiafa; Wang, Zhongyan

2011-03-01

The aim of this work was to research a bioprocess for bioethanol production from raw sweet potato by Saccharomyces cerevisiae at laboratory, pilot and industrial scales. The fermentation mode, inoculum size and pressure from different gases were determined in laboratory. The maximum ethanol concentration, average ethanol productivity rate and yield of ethanol after fermentation in laboratory scale (128.51 g/L, 4.76 g/L/h and 91.4%) were satisfactory with small decrease at pilot scale (109.06 g/L, 4.89 g/L/h and 91.24%) and industrial scale (97.94 g/L, 4.19 g/L/h and 91.27%). When scaled up, the viscosity caused resistance to fermentation parameters, 1.56 AUG/g (sweet potato mash) of xylanase decreased the viscosity from approximately 30000 to 500 cp. Overall, sweet potato is a attractive feedstock for be bioethanol production from both the economic standpoints and environmentally friendly. Copyright © 2011 Elsevier Ltd. All rights reserved.

Installation Restoration Program Records Search for Bergstrom Air Force Base, Texas.

DTIC Science & Technology

1983-07-01

August 1981. "Pilot Plant Study of Copper , Zinc, and Trivalent Chromium Removal by Adsorbing Colloid Foam Flotation ." M.S. Thesis, Vanderbilt...graduate school and one of his activities included researching the removal of heavy metals, including copper , zinc and trivalent chromium, using a large...scale adsorbing colloid foam flotation pilot plant. Professional Registration Engineer-In-Training, Florida % -7. GREGORY T. MCINTYRE Membership in

Preliminary study of the pilot's workload during emergency procedures in helicopters air operations.

PubMed

Bezerra, Flávio G V; Ribeiro, Selma L O

2012-01-01

Military air operations and law enforcement operations in helicopters are examples of activities that require high performance of the operator. This article aimed at presenting a preliminary analysis of data obtained in the initial study in order to validate the instruments and the research protocol that focuses on the analysis of the workload imposed on helicopter pilots in emergency situations. The research was conducted in an environment of real flight training and used the NASA-TLX Scale to assess the workload and an interview guide to obtain reports on the main tasks performed. Preliminary data obtained is related to the participation of 10 (ten) volunteer pilots with experience in different types of helicopters. Four scenarios involving helicopter emergency procedures of HB-350 "Squirrel" were outlined. For this article, the analysis used only the data regarding the Physical and Mental Demands of the NASA-TLX Scale. Preliminarily, the results indicate that the "time pressure" as a factor contributing to increase mental requirement in emergency situations in flight, and that this increase was reflected in the request of mental processes such as: identification of the breakdown, attention and monitoring parameters. Future steps include extending the sample and adding physiological tools to better understand the effects of these types of emergencies on pilot performance and flight safety.

Subsurface Monitoring of CO2 Sequestration - A Review and Look Forward

NASA Astrophysics Data System (ADS)

Daley, T. M.

2012-12-01

The injection of CO2 into subsurface formations is at least 50 years old with large-scale utilization of CO2 for enhanced oil recovery (CO2-EOR) beginning in the 1970s. Early monitoring efforts had limited measurements in available boreholes. With growing interest in CO2 sequestration beginning in the 1990's, along with growth in geophysical reservoir monitoring, small to mid-size sequestration monitoring projects began to appear. The overall goals of a subsurface monitoring plan are to provide measurement of CO2 induced changes in subsurface properties at a range of spatial and temporal scales. The range of spatial scales allows tracking of the location and saturation of the plume with varying detail, while finer temporal sampling (up to continuous) allows better understanding of dynamic processes (e.g. multi-phase flow) and constraining of reservoir models. Early monitoring of small scale pilots associated with CO2-EOR (e.g., the McElroy field and the Lost Hills field), developed many of the methodologies including tomographic imaging and multi-physics measurements. Large (reservoir) scale sequestration monitoring began with the Sleipner and Weyburn projects. Typically, large scale monitoring, such as 4D surface seismic, has limited temporal sampling due to costs. Smaller scale pilots can allow more frequent measurements as either individual time-lapse 'snapshots' or as continuous monitoring. Pilot monitoring examples include the Frio, Nagaoka and Otway pilots using repeated well logging, crosswell imaging, vertical seismic profiles and CASSM (continuous active-source seismic monitoring). For saline reservoir sequestration projects, there is typically integration of characterization and monitoring, since the sites are not pre-characterized resource developments (oil or gas), which reinforces the need for multi-scale measurements. As we move beyond pilot sites, we need to quantify CO2 plume and reservoir properties (e.g. pressure) over large scales, while still obtaining high resolution. Typically the high-resolution (spatial and temporal) tools are deployed in permanent or semi-permanent borehole installations, where special well design may be necessary, such as non-conductive casing for electrical surveys. Effective utilization of monitoring wells requires an approach of modular borehole monitoring (MBM) were multiple measurements can be made. An example is recent work at the Citronelle pilot injection site where an MBM package with seismic, fluid sampling and distributed fiber sensing was deployed. For future large scale sequestration monitoring, an adaptive borehole-monitoring program is proposed.

Development and psychometric evaluation of the Primary Health Care Engagement (PHCE) Scale: a pilot survey of rural and remote nurses.

PubMed

Kosteniuk, Julie G; Wilson, Erin C; Penz, Kelly L; MacLeod, Martha L P; Stewart, Norma J; Kulig, Judith C; Karunanayake, Chandima P; Kilpatrick, Kelley

2016-01-01

To report the development and psychometric evaluation of a scale to measure rural and remote (rural/remote) nurses' perceptions of the engagement of their workplaces in key dimensions of primary health care (PHC). Amidst ongoing PHC reforms, a comprehensive instrument is needed to evaluate the degree to which rural/remote health care settings are involved in the key dimensions that characterize PHC delivery, particularly from the perspective of professionals delivering care. This study followed a three-phase process of instrument development and psychometric evaluation. A literature review and expert consultation informed instrument development in the first phase, followed by an iterative process of content evaluation in the second phase. In the final phase, a pilot survey was undertaken and item discrimination analysis employed to evaluate the internal consistency reliability of each subscale in the preliminary 60-item Primary Health Care Engagement (PHCE) Scale. The 60-item scale was subsequently refined to a 40-item instrument. The pilot survey sample included 89 nurses in current practice who had experience in rural/remote practice settings. Participants completed either a web-based or paper survey from September to December, 2013. Following item discrimination analysis, the 60-item instrument was refined to a 40-item PHCE Scale consisting of 10 subscales, each including three to five items. Alpha estimates of the 10 refined subscales ranged from 0.61 to 0.83, with seven of the subscales demonstrating acceptable reliability (α ⩾ 0.70). The refined 40-item instrument exhibited good internal consistency reliability (α=0.91). The 40-item PHCE Scale may be considered for use in future studies regardless of locale, to measure the extent to which health care professionals perceive their workplaces to be engaged in key dimensions of PHC.

Developing a Measurement for Task Complexity in Flight.

PubMed

Zheng, Yiyuan; Lu, Yanyu; Wang, Zhen; Huang, Dan; Fu, Shan

2015-08-01

Task complexity is regarded as an essential metric that is related to a pilot's performance and workload. Normally, pilots follow Standard Operating Procedures (SOPs) during a flight. In this study, we developed a measurement named Task Complexity in Flight (TCIF) to represent the task complexity in the SOPs. The TCIF measurement combined four complexity components into one index: actions logic complexity (ALC), actions size complexity (ASC), information control exchange complexity (ICEC), and control mode complexity (CMC).To verify the measurement, we calculated 11 tasks during the takeoff and landing phases from the SOPs, and invited 10 pilots to perform the same tasks in a flight simulator. After flight, the TCIF results were compared with two workload measurements: the Bedford scale and heart rate. The results of TCIF and the 4 components of the 11 tasks were calculated. Further, the TCIF results showed a significant correlation with the Bedford scores (R=0.851) and were also consistent with the difference in heart rate (R=0.816). Therefore, with the increased TCIF results, both the Bedford scale and the difference in heart rate increased. TCIF was proposed based on the flight operating conditions. Although additional studies of TCIF are necessary, the results of this study suggest this measurement could effectively indicate task complexity in flight, and could also be used to guide pilot training and task allocation on the flight deck.

Field-scale simulation of chemical flooding

DOE Office of Scientific and Technical Information (OSTI.GOV)

Saad, N.

1989-01-01

A three-dimensional compositional chemical flooding simulator (UTCHEM) has been improved. The new mathematical formulation, boundary conditions, and a description of the physicochemical models of the simulator are presented. This improved simulator has been used for the study of the low tension pilot project at the Big Muddy field near Casper, Wyoming. Both the tracer injection conducted prior to the injection of the chemical slug, and the chemical flooding stages of the pilot project, have been analyzed. Not only the oil recovery but also the tracers, polymer, alcohol and chloride histories have been successfully matched with field results. Simulation results indicatemore » that, for this fresh water reservoir, the salinity gradient during the preflush and the resulting calcium pickup by the surfactant slug played a major role in the success of the project. In addition, analysis of the effects of the crossflow on the performance of the pilot project indicates that, for the well spacing of the pilot, crossflow does not play as important a role as it might for a large-scale project. To improve the numerical efficiency of the simulator, a third order convective differencing scheme has been applied to the simulator. This method can be used with non-uniform mesh, and therefore is suited for simulation studies of large-scale multiwell heterogeneous reservoirs. Comparison of the results with one and two dimensional analytical solutions shows that this method is effective in eliminating numerical dispersion using relatively large grid blocks. Results of one, two and three-dimensional miscible water/tracer flow, water flooding, polymer flooding, and micellar-polymer flooding test problems, and results of grid orientation studies, are presented.« less

ECONOMIC ANALYSIS OF TREATMENT TECHNOLOGIES TO ACHIEVE VOC (VOLATILE ORGANIC CHEMICALS) REMOVAL TO SAFE LEVELS

EPA Science Inventory

In the VOC regulations both Granular Activated Carbon (GAC) and Packed Tower Aeration (PTA) have been designated as Best Available Treatment. DWRD has performed a great deal of research both at the bench, pilot and field scale on the use of GAC and pilot and field scale research ...

REVIEW OF BENCH-, PILOT-, AND FULL-SCALE ORIMULSION (R) COMBUSTION TESTS

EPA Science Inventory

The paper gives results of a review of bench-, pilot-, and full-scale Orimulsion combustion tests. A fossil fuel marketed by its producer, Petroleos de Venezuela, S.A. (PdVSA), since the late 1980s as an alternative to coal and heavy fuel oil, Orimulsion is a bitumen-in-water em...

DEMONSTRATION OF PILOT-SCALE PERVAPORATION SYSTEMS FOR VOLATILE ORGANIC COMPOUND REMOVAL FROM A SURFACTANT ENHANCED AQUIFER REMEDIATION FLUID. II. HOLLOW FIBER MEMBRANE MODULES

EPA Science Inventory

Pilot-scale demonstration of pervaporation-based removal of volatile organic compounds from a surfactant enhanced aquifer remediation (SEAR) fluid has been conducted at USEPA's Test & Evaluation Facility using hollow fiber membrane modules. The membranes consisted of microporous...

Development of a Pilot Scale Process to Sequester Aflatoxin and Release Bioactive Peptides from Highly Contaminated Peanut Meal

USDA-ARS?s Scientific Manuscript database

Peanut meal (PM) is the high protein by-product remaining after commercial extraction of peanut oil. PM applications are limited because of typical high concentrations of aflatoxin. For the first time, pilot-scale extraction of protein and sequestration of aflatoxin from PM were evaluated. Aqueous...

Final Pilot Performance Rating Scales.

ERIC Educational Resources Information Center

Horner, Walter R.; And Others

These rating scales are intended for evaluation of student pilot performance. Each student is evaluated individually on the basis of video recordings of the student in flight. Ten point rating lines are used for the ten criterion performance elements of each of three maneuvers, (1) Final Turn to Landing, (2) Lazy Eight, and (3) Vertical S "A".…

Effect of lift-to-drag ratio in pilot rating of the HL-20 landing task

NASA Technical Reports Server (NTRS)

Jackson, E. B.; Rivers, Robert A.; Bailey, Melvin L.

1993-01-01

A man-in-the-loop simulation study of the handling qualities of the HL-20 lifting-body vehicle was made in a fixed-base simulation cockpit at NASA Langley Research Center. The purpose of the study was to identify and substantiate opportunities for improving the original design of the vehicle from a handling qualities and landing performance perspective. Using preliminary wind-tunnel data, a subsonic aerodynamic model of the HL-20 was developed. This model was adequate to simulate the last 75-90 s of the approach and landing. A simple flight-control system was designed and implemented. Using this aerodynamic model as a baseline, visual approaches and landings were made at several vehicle lift-to-drag ratios. Pilots rated the handling characteristics of each configuration using a conventional numerical pilot-rating scale. Results from the study showed a high degree of correlation between the lift-to-drag ratio and pilot rating. Level 1 pilot ratings were obtained when the L/D ratio was approximately 3.8 or higher.

Effect of lift-to-drag ratio in pilot rating of the HL-20 landing task

NASA Astrophysics Data System (ADS)

Jackson, E. B.; Rivers, Robert A.; Bailey, Melvin L.

1993-10-01

A man-in-the-loop simulation study of the handling qualities of the HL-20 lifting-body vehicle was made in a fixed-base simulation cockpit at NASA Langley Research Center. The purpose of the study was to identify and substantiate opportunities for improving the original design of the vehicle from a handling qualities and landing performance perspective. Using preliminary wind-tunnel data, a subsonic aerodynamic model of the HL-20 was developed. This model was adequate to simulate the last 75-90 s of the approach and landing. A simple flight-control system was designed and implemented. Using this aerodynamic model as a baseline, visual approaches and landings were made at several vehicle lift-to-drag ratios. Pilots rated the handling characteristics of each configuration using a conventional numerical pilot-rating scale. Results from the study showed a high degree of correlation between the lift-to-drag ratio and pilot rating. Level 1 pilot ratings were obtained when the L/D ratio was approximately 3.8 or higher.

Removal of volatile organic compounds at extreme shock-loading using a scaled-up pilot rotating drum biofilter.

PubMed

Sawvel, Russell A; Kim, Byung; Alvarez, Pedro J J

2008-11-01

A pilot-scale rotating drum biofilter (RDB), which is a novel biofilter design that offers flexible flow-through configurations, was used to treat complex and variable volatile organic compound (VOC) emissions, including shock loadings, emanating from paint drying operations at an Army ammunition plant. The RDB was seeded with municipal wastewater activated sludge. Removal efficiencies up to 86% and an elimination capacity of 5.3 g chemical oxygen demand (COD) m(-3) hr(-1) were achieved at a filter-medium contact time of 60 sec. Efficiency increased at higher temperatures that promote higher biological activity, and decreased at lower pH, which dropped down to pH 5.5 possibly as a result of carbon dioxide and volatile fatty acid production and ammonia consumption during VOC degradation. In comparison, other studies have shown that a bench-scale RDB could achieve a removal efficiency of 95% and elimination capacity of 331 g COD m(-3) hr(-1). Sustainable performance of the pilot-scale RDB was challenged by the intermittent nature of painting operations, which typically resulted in 3-day long shutdown periods when bacteria were not fed. This challenge was overcome by adding sucrose (2 g/L weekly) as an auxiliary substrate to sustain metabolic activity during shutdown periods.

Comparative research on phosphorus removal by pilot-scale vertical flow constructed wetlands using steel slag and modified steel slag as substrates.

PubMed

Yun, Yupan; Zhou, Xiaoqin; Li, Zifu; Uddin, Sayed Mohammad Nazim; Bai, Xiaofeng

2015-01-01

This research mainly focused on the phosphorus removal performance of pilot-scale vertical flow constructed wetlands with steel slag (SS) and modified steel slag (MSS). First, bench-scale experiments were conducted to evaluate the phosphorus adsorption capacity. Results showed that the Langmuir model could better describe the adsorption characteristics of the two materials; the maximum adsorption of MSS reached 12.7 mg/g, increasing by 34% compared to SS (9.5 mg/g). Moreover, pilot-scale constructed wetlands with SS and MSS were set up outdoors. Then, the influence of hydraulic retention time (HRT) and phosphorus concentration in phosphorus removal for two wetlands were investigated. Results revealed that better performance of the two systems could be achieved with an HRT of 2 d and phosphorus concentration in the range of 3-4.5 mg/L; the system with MSS had a better removal efficiency than the one with SS in the same control operation. Finally, the study implied that MSS could be used as a promising substrate for wetlands to treat wastewater with a high phosphorus concentration. However, considering energy consumption, SS could be regarded as a better alternative for substrate when treating sewage with a low phosphorus concentration.

Visual health screening by schoolteachers in remote communities of Peru: implementation research

PubMed Central

Latorre-Arteaga, Sergio; Gil-González, Diana; Bascarán, Covadonga; Núñez, Richard Hurtado; Morales, María del Carmen Peral; Orihuela, Guillermo Carrillo

2016-01-01

Abstract Objective To describe the adaptation and scaling-up of an intervention to improve the visual health of children in the Apurimac region, Peru. Methods In a pilot screening programme in 2009–2010, 26 schoolteachers were trained to detect and refer visual acuity problems in schoolchildren in one district in Apurimac. To scale-up the intervention, lessons learnt from the pilot were used to design strategies for: (i) strengthening multisector partnerships; (ii) promoting the engagement and participation of teachers and (iii) increasing children’s attendance at referral eye clinics. Implementation began in February 2015 in two out of eight provinces of Apurimac, including hard-to-reach communities. We made an observational study of the processes and outcomes of adapting and scaling-up the intervention. Qualitative and quantitative analyses were made of data collected from March 2015 to January 2016 from programme documents, routine reports and structured evaluation questionnaires completed by teachers. Findings Partnerships were expanded after sharing the results of the pilot phase. Training was completed by 355 teachers and directors in both provinces, belonging to 315 schools distributed in 24 districts. Teachers’ appraisal of the training achieved high positive scores. Outreach eye clinics and subsidies for glasses were provided for poorer families. Data from six districts showed that attendance at the eye clinic increased from 66% (45/68 children referred) in the pilot phase to 92% (237/259) in the implementation phase. Conclusion Adaptation to the local context allowed the scaling-up of an intervention to improve visual health in children and enhanced the equity of the programme. PMID:27708470

Balance exercise in patients with chronic sensory ataxic neuropathy: a pilot study.

PubMed

Riva, Nilo; Faccendini, Simone; Lopez, Ignazio D; Fratelli, Annamaria; Velardo, Daniele; Quattrini, Angelo; Gatti, Roberto; Comi, Giancarlo; Comola, Mauro; Fazio, Raffaella

2014-06-01

Although exercise therapy is considered part of the treatment of neuropathic patients, and somatosensory input is essential for motor learning, performance and neural plasticity, rehabilitation of patients with sensory ataxia has received little attention so far. The aim of this prospective pilot study was to explore the short- and medium-term efficacy of a 3-week intensive balance and treadmill exercise program in chronic ataxic neuropathy patients; 20 consecutive patients with leg overall disability sum score (ODSS-leg) ≥2, absent/mild motor signs, clinical and therapeutic stability ≥4 months were enrolled. Evaluations were done at baseline, at the end of treatment and at 3- and 6-month follow-up. Outcome measurements included: ODSS-leg, Berg balance scale, 6-min walk distance, and the functional independence measure (FIM) scale. The short-form-36 health status scale (SF-36) was used to measure health-related quality of life (HRQoL). ODSS-leg improved significantly compared with baseline, 3 weeks, 3 months (primary outcome), and 6 months follow-up. A significant improvement in all functional secondary outcome measurements and in some SF-36 subscales was also observed. This pilot study suggests that balance exercise is safe and well tolerated and might be effective in ameliorating disability and HRQoL in patients with chronic peripheral sensory ataxia. © 2014 Peripheral Nerve Society.

Development and validation of the client engagement and service use scale: A pilot study.

PubMed

Kline, Emily R; DeTore, Nicole R; Keefe, Kristen; Seidman, Larry J; Srihari, Vinod H; Keshavan, Matcheri S; Guyer, Margaret

2018-05-12

Specialized treatment for first episode psychosis offers clients a menu of services coordinated within a specialized treatment team. To enhance the impact of these services, promoting engagement and preventing early treatment drop-out is critical. However, engagement is poorly tracked and typically quantified through proxy variables such as session attendance, medication adherence, or working alliance. The aim of this study is to introduce and pilot a new measure of engagement for first episode psychosis coordinated specialty care, the Client Engagement and Service Use Scale (CENSUS). The CENSUS was evaluated for reliability and validated against the Service Engagement Scale and an appointment count for a small sample (N = 10) of first episode clients. The measure was also evaluated for acceptability by a consumer advocacy group. Clinicians achieved high inter-rater reliability after minimal training. CENSUS items demonstrated medium to large correlations with other measures of engagement. Feedback from the consumer group emphasized that clinicians should ask questions in a way that is nonjudgmental and successfully elicits authentic client feedback about their service preferences. This pilot study yielded preliminary evidence of reliability and validity, suggesting that the CENSUS is a useful and novel tool for tracking and differentiating degrees of client engagement across multiple intervention components and for facilitating structured discussions regarding clients' service utilization and preferences. Copyright © 2018. Published by Elsevier B.V.

CoDuSe group exercise programme improves balance and reduces falls in people with multiple sclerosis: A multi-centre, randomized, controlled pilot study.

PubMed

Carling, Anna; Forsberg, Anette; Gunnarsson, Martin; Nilsagård, Ylva

2017-09-01

Imbalance leading to falls is common in people with multiple sclerosis (PwMS). To evaluate the effects of a balance group exercise programme (CoDuSe) on balance and walking in PwMS (Expanded Disability Status Scale, 4.0-7.5). A multi-centre, randomized, controlled single-blinded pilot study with random allocation to early or late start of exercise, with the latter group serving as control group for the physical function measures. In total, 14 supervised 60-minute exercise sessions were delivered over 7 weeks. Pretest-posttest analyses were conducted for self-reported near falls and falls in the group starting late. Primary outcome was Berg Balance Scale (BBS). A total of 51 participants were initially enrolled; three were lost to follow-up. Post-intervention, the exercise group showed statistically significant improvement ( p = 0.015) in BBS and borderline significant improvement in MS Walking Scale ( p = 0.051), both with large effect sizes (3.66; -2.89). No other significant differences were found between groups. In the group starting late, numbers of falls and near falls were statistically significantly reduced after exercise compared to before ( p < 0.001; p < 0.004). This pilot study suggests that the CoDuSe exercise improved balance and reduced perceived walking limitations, compared to no exercise. The intervention reduced falls and near falls frequency.

The British Sign Language Versions of the Patient Health Questionnaire, the Generalized Anxiety Disorder 7-Item Scale, and the Work and Social Adjustment Scale

ERIC Educational Resources Information Center

Rogers, Katherine D.; Young, Alys; Lovell, Karina; Campbell, Malcolm; Scott, Paul R.; Kendal, Sarah

2013-01-01

The present study is aimed to translate 3 widely used clinical assessment measures into British Sign Language (BSL), to pilot the BSL versions, and to establish their validity and reliability. These were the Patient Health Questionnaire (PHQ-9), the Generalized Anxiety Disorder 7-item (GAD-7) scale, and the Work and Social Adjustment Scale (WSAS).…

Psychometric properties of the Chinese-version Quality of Nursing Work Life Scale.

PubMed

Lee, Ya-Wen; Dai, Yu-Tzu; McCreary, Linda L; Yao, Grace; Brooks, Beth A

2014-09-01

In this study, we developed and tested the psychometric properties of the Chinese-version Quality of Nursing Work Life Scale along seven subscales: supportive milieu with security and professional recognition, work arrangement and workload, work/home life balance, head nurse's/supervisor's management style, teamwork and communication, nursing staffing and patient care, and milieu of respect and autonomy. An instrument-development procedure with three phases was conducted in seven hospitals in 2010-2011. Phase I comprised translation and the cultural-adaptation process, phase II comprised a pilot study, and phase III comprised a field-testing process. Purposive sampling was used in the pilot study (n = 150) and the large field study (n = 1254). Five new items were added, and 85.7% of the original items were retained in the 41 item Chinese version. Principal component analysis revealed that a model accounted for 56.6% of the variance with acceptable internal consistency, concurrent validity, and discriminant validity. This study gave evidence of reliability and validity of the 41 item Chinese-version Quality of Nursing Work Life Scale. © 2014 Wiley Publishing Asia Pty Ltd.

The Response Scale for the Intellectual Disability Module of the WHOQOL: 5-Point or 3-Point?

ERIC Educational Resources Information Center

Fang, J.; Fleck, M. P.; Green, A.; McVilly, K.; Hao, Y.; Tan, W.; Fu, R.; Power, M.

2011-01-01

Objective: To deal with the question of whether a 5-point response Likert scale should be changed to a 3-point scale when used in the field testing of people with intellectual disabilities (IDs), which was raised after the pilot study of World Health Organization Quality of Life (WHOQOL)-DIS, a module being developed with the World Health…

A Scale to Assist the Diagnosis of Autism and Asperger's Disorder in Adults (RAADS): A Pilot Study

ERIC Educational Resources Information Center

Ritvo, Riva Ariella; Ritvo, Edward R.; Guthrie, Donald; Yuwiler, Arthur; Ritvo, Max Joseph; Weisbender, Leo

2008-01-01

An empirically based 78 question self-rating scale based on DSM-IV-TR and ICD-10 criteria was developed to assist clinicians' diagnosis of adults with autism and Asperger's Disorder-the Ritvo Autism and Asperger's Diagnostic Scale (RAADS). It was standardized on 17 autistic and 20 Asperger's Disorder and 57 comparison subjects. Both autistic and…

Low-dose aspirin in polycythaemia vera: a pilot study. Gruppo Italiano Studio Policitemia (GISP).

PubMed

1997-05-01

In this pilot study, aimed at exploring the feasibility of a large-scale trial of low-dose aspirin in polycythaemia vera (PV), 112 PV patients (42 females, 70 males. aged 17-80 years) were selected for not having a clear indication for, or contraindication to, aspirin treatment and randomized to receive oral aspirin (40 mg/d) or placebo. Follow-up duration was 16 +/- 6 months. Measurements of thromboxane A2 production during whole blood clotting demonstrated complete inhibition of platelet cyclooxygenase activity in patients receiving aspirin. Aspirin administration was not associated with any bleeding complication. Within the limitations of the small sample size, this study indicates that a biochemically effective regimen of antiplatelet therapy is well tolerated in patients with polycythaemia vera and that a large-scale placebo-controlled trial is feasible.

[Efficacy of Arnica in varicose vein surgery: results of a randomized, double-blind, placebo-controlled pilot study].

PubMed

Wolf, M; Tamaschke, C; Mayer, W; Heger, M

2003-10-01

In homeopathy ARNICA is widely used as a woundhealing medication and for the treatment of hematomas. In this pilot study the efficacy and safety of ARNICA D12 in patients following varicose vein surgery were investigated. Prospective, randomized, double-blind, placebo-controlled pilot trial according to ICH GCP guidelines. The study was conducted by a surgeon at the Angiosurgical Clinic, Berlin- Buch. After randomized allocation, 60 patients received either ARNICA D12 or placebo. Start of medication occurred the evening before operation with 5 globules. On the operation day one preoperative and hourly postoperative dosages after awakening were given. On days 2-14 of the study 5 globules 3 times a day were given. OUTCOME CRITERIA: Surface (in cm(2) and using a three-point verbal rating scale) and intensity of hematomas induced by operation, complications of wound healing, and intensity of pain (five-point verbal rating scale) as well as efficacy and safety of the study medication were assessed. Hematoma surface was reduced (from day 7 to day 14) under ARNICA by 75.5% and under placebo by 71.5% (p = 0.4726). The comparison of hematoma surface (small, medium, large) using the verbal rating scale yielded a value of p = 0.1260. Pain score decreased by 1.0 +/- 2.2 points under ARNICA and 0.3 +/- 0.8 points under placebo (p = 0.1977). Remission or improvement of pain was observed in 43.3% of patients in the ARNICA group and in 27.6% of patients in the placebo group. Tolerability was rated as very good in all cases. The results of this pilot study showed a trend towards a beneficial effect of ARNICA D12 with regard to reduction of hematoma and pain during the postoperative course. For a statistically significant proof of efficacy of ARNICA D12 in patients following varicose vein surgery a larger sample size is necessary. Copyright 2003 S. Karger GmbH, Freiburg

Taking the first step towards entrenching mental health in the workplace: insights from a pilot study among HR personnel in Nigeria.

PubMed

Atilola, O; Akinyemi, O; Atilola, B

2014-01-01

The continued relevance of optimal employee mental health to sustainable human capital development in the workplace underscores the need to start harnessing all resources that can be mobilized to promote the entrenchment of workplace mental health. The strategic place of workplace Human Resource (HR) units in formulating and implementing workplace welfare schemes makes them potential partners. To actualize this, it is important to initially assess the preparedness of HR personnel for, and the possible barriers to entrenching mental health in the workplace. To suggest the initial course of action and to serve as a template for a robust large-scale study, we conduct a pilot assessment of the experience with, attitudes towards, and level of prioritization of mental health in the workplace among a cohort of HR personnel in Nigeria. Participants were recruited in the course of a seminar/workshop and questionnaires were developed by authors to assess variables of interest. Attitudes were examined using an adapted form of the Link's Discrimination-Devaluation (LD-D) scale. A total of 90 human-resource personnel completed the questionnaires. Only 16% of the participants reported having handled the case of an employee with a suspected mental health problem in the preceding 2 years. Attitudes toward employees and prospective employees with mental illness were largely poor. For instance, more than 70% were likely to consider for employment someone with a pre-existing physical disability than for someone with a history of mental illness. In terms of workplace health promotion priorities, physical health seminars took wide precedence over mental health seminars. The preliminary findings of this pilot study justify a need to conduct a large scale study. Significant challenges encountered in the course of this pilot study were highlighted while insights were drawn for the conduct of the main study/project.

[The prevalence of snoring in male pilots].

PubMed

Wang, Wan-er; Zhu, Guang-qing; Zhang, Ji-dong; Li, Rong; Wang, Yan-yan; Zhang, Yu-zhen; Liu, Ju-qin; He, Quan-ying

2008-09-01

To investigate and analysis the prevalence and risk factors of snoring and excessive daytime sleepiness among male pilots. 1108 subjects were derived from a random sample of pilots. They were asked to answer the questions from a questionnaire concerning their snoring and daytime sleepiness, etc. 1054 questionnaire were available for evaluation. The overall prevalence of snoring among male pilots was 51.04% (538/1054), while moderate and severe snorers accounted for 26.28% (227/1054). The prevalence of snoring among male pilots aged over 30 yr was 63.68% (426/669). The prevalence and severity of snoring increase with age and BMI. Age, overweight and obesity, alcohol ingestion and family history of snoring were associated with the prevalence and severity of snoring. There was significant difference in Epworth sleepiness scale scores among without snoring group and various severity of snoring groups (chi2 = 16.948, P < 0.05). The prevalence of snoring is high in male pilots. The Epworth sleepiness scale score increase with increasing degree of snoring. Doctors should pay more attention to snoring in male pilot.

Low-nitrogen oxides combustion of dried sludge using a pilot-scale cyclone combustor with recirculation.

PubMed

Shim, Sung Hoon; Jeong, Sang Hyun; Lee, Sang-Sup

2015-04-01

Recently, numerical and experimental studies have been conducted to develop a moderate or intense low-oxygen dilution (MILD) combustion technology for solid fuels. The study results demonstrated that intense recirculation inside the furnace by high-momentum air is a key parameter to achieve the MILD combustion of solid fuels. However, the high-velocity air requires a significant amount of electricity consumption. A cyclone-type MILD combustor was therefore designed and constructed in the authors' laboratory to improve the recirculation inside the combustor. The laboratory-scale tests yielded promising results for the MILD combustion of dried sewage sludge. To achieve pilot-scale MILD combustion of dried sludge in this study, the effects of geometric parameters such as the venturi tube configuration, the air injection location, and the air nozzle diameter were investigated. With the optimized geometric and operational conditions, the pilot-scale cyclone combustor demonstrated successful MILD combustion of dried sludge at a rate of 75 kg/hr with an excess air ratio of 1.05. A horizontal cyclone combustor with recirculation demonstrated moderate or intense low-oxygen dilution (MILD) combustion of dried sewage sludge at a rate of 75 kg/hr. Optimizing only geometric and operational conditions of the combustor reduced nitrogen oxide (NOx) emissions to less than 75 ppm. Because the operating cost of the MILD combustor is much lower than that of the selective catalytic reduction (SCR) applied to the conventional combustor, MILD combustion technology with the cyclone type furnace is an eligible option for reducing NOx emissions from the combustion of dried sewage sludge.

Comprehensive Evaluation of Biological Growth Control by Chlorine-Based Biocides in Power Plant Cooling Systems Using Tertiary Effluent

PubMed Central

Chien, Shih-Hsiang; Dzombak, David A.; Vidic, Radisav D.

2013-01-01

Abstract Recent studies have shown that treated municipal wastewater can be a reliable cooling water alternative to fresh water. However, elevated nutrient concentration and microbial population in wastewater lead to aggressive biological proliferation in the cooling system. Three chlorine-based biocides were evaluated for the control of biological growth in cooling systems using tertiary treated wastewater as makeup, based on their biocidal efficiency and cost-effectiveness. Optimal chemical regimens for achieving successful biological growth control were elucidated based on batch-, bench-, and pilot-scale experiments. Biocide usage and biological activity in planktonic and sessile phases were carefully monitored to understand biological growth potential and biocidal efficiency of the three disinfectants in this particular environment. Water parameters, such as temperature, cycles of concentration, and ammonia concentration in recirculating water, critically affected the biocide performance in recirculating cooling systems. Bench-scale recirculating tests were shown to adequately predict the biocide residual required for a pilot-scale cooling system. Optimal residuals needed for proper biological growth control were 1, 2–3, and 0.5–1 mg/L as Cl2 for NaOCl, preformed NH2Cl, and ClO2, respectively. Pilot-scale tests also revealed that Legionella pneumophila was absent from these cooling systems when using the disinfectants evaluated in this study. Cost analysis showed that NaOCl is the most cost-effective for controlling biological growth in power plant recirculating cooling systems using tertiary-treated wastewater as makeup. PMID:23781129

Solar photocatalitycal treatment of carbofuran at lab and pilot scale: effect of classical parameters, evaluation of the toxicity and analysis of organic by-products.

PubMed

Lopez-Alvarez, Blady; Torres-Palma, Ricardo A; Peñuela, Gustavo

2011-07-15

In this work the TiO(2) solar-photocatalytical degradation of the pesticide carbofuran (CBF) in water, at lab and pilot scale, was studied. At lab scale the evaluation of CBF concentration (14-282 μmol L(-1)) showed that the system followed a Langmuir-Hinshelwood kinetics type. TiO(2) concentration (0.05-2 g L(-1)) and initial pH (3-9) were also evaluated and optimized using the surface response methodology and the Pareto diagram. In the range of variables studied, initial pH 7.60 and 1.43 g L(-1) of TiO(2) favoured the efficiency of the process. Under optimal conditions the evolution of substrate, chemical oxygen demand, dissolved organic carbon, toxicity and organics by-products were evaluated. In the pilot scale tests, using direct sunlight, 55 mg L(-1) of CBF in a commercial formulation was eliminated after 420 min; while after 900 min of treatment 80% of toxicity (1/E(50) on Vibrium Fischeri), 80% of chemical oxygen demand and 60% of dissolved organic carbon were removed. The analysis and evolution of five CBF by-products, as well the evaluation of the treatment in the presence of isopropanol or using acetonitrile as a solvent suggest that the degradation is mainly carried out by OH radical attack. Finally, a schema depicting the main degradation pathway is proposed. Copyright © 2011 Elsevier B.V. All rights reserved.

Comprehensive Evaluation of Biological Growth Control by Chlorine-Based Biocides in Power Plant Cooling Systems Using Tertiary Effluent.

PubMed

Chien, Shih-Hsiang; Dzombak, David A; Vidic, Radisav D

2013-06-01

Recent studies have shown that treated municipal wastewater can be a reliable cooling water alternative to fresh water. However, elevated nutrient concentration and microbial population in wastewater lead to aggressive biological proliferation in the cooling system. Three chlorine-based biocides were evaluated for the control of biological growth in cooling systems using tertiary treated wastewater as makeup, based on their biocidal efficiency and cost-effectiveness. Optimal chemical regimens for achieving successful biological growth control were elucidated based on batch-, bench-, and pilot-scale experiments. Biocide usage and biological activity in planktonic and sessile phases were carefully monitored to understand biological growth potential and biocidal efficiency of the three disinfectants in this particular environment. Water parameters, such as temperature, cycles of concentration, and ammonia concentration in recirculating water, critically affected the biocide performance in recirculating cooling systems. Bench-scale recirculating tests were shown to adequately predict the biocide residual required for a pilot-scale cooling system. Optimal residuals needed for proper biological growth control were 1, 2-3, and 0.5-1 mg/L as Cl 2 for NaOCl, preformed NH 2 Cl, and ClO 2 , respectively. Pilot-scale tests also revealed that Legionella pneumophila was absent from these cooling systems when using the disinfectants evaluated in this study. Cost analysis showed that NaOCl is the most cost-effective for controlling biological growth in power plant recirculating cooling systems using tertiary-treated wastewater as makeup.

Pilot-scale cultivation of wall-deficient transgenic Chlamydomonas reinhardtii strains expressing recombinant proteins in the chloroplast.

PubMed

Zedler, Julie A Z; Gangl, Doris; Guerra, Tiago; Santos, Edgar; Verdelho, Vitor V; Robinson, Colin

2016-08-01

Microalgae have emerged as potentially powerful platforms for the production of recombinant proteins and high-value products. Chlamydomonas reinhardtii is a potentially important host species due to the range of genetic tools that have been developed for this unicellular green alga. Transformation of the chloroplast genome offers important advantages over nuclear transformation, and a wide range of recombinant proteins have now been expressed in the chloroplasts of C. reinhardtii strains. This is often done in cell wall-deficient mutants that are easier to transform. However, only a single study has reported growth data for C. reinhardtii grown at pilot scale, and the growth of cell wall-deficient strains has not been reported at all. Here, we report the first pilot-scale growth study for transgenic, cell wall-deficient C. reinhardtii strains. Strains expressing a cytochrome P450 (CYP79A1) or bifunctional diterpene synthase (cis-abienol synthase, TPS4) were grown for 7 days under mixotrophic conditions in a Tris-acetate-phosphate medium. The strains reached dry cell weights of 0.3 g/L within 3-4 days with stable expression levels of the recombinant proteins during the whole upscaling process. The strains proved to be generally robust, despite the cell wall-deficient phenotype, but grew poorly under phototrophic conditions. The data indicate that cell wall-deficient strains may be highly amenable for transformation and suitable for commercial-scale operations under mixotrophic growth regimes.

Field Testing of a Wet FGD Additive for Enhanced Mercury Control - Task 5 Full-Scale Test Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gary Blythe; MariJon Owens

2007-12-01

This Topical Report summarizes progress on Cooperative Agreement DE-FC26-04NT42309, 'Field Testing of a Wet FGD Additive'. The objective of the project is to demonstrate the use of two flue gas desulfurization (FGD) additives, Evonik Degussa Corporation's TMT-15 and Nalco Company's Nalco 8034, to prevent the re-emission of elemental mercury (Hg{sup 0}) in flue gas exiting wet FGD systems on coal-fired boilers. Furthermore, the project intends to demonstrate whether the additive can be used to precipitate most of the mercury (Hg) removed in the wet FGD system as a fine salt that can be separated from the FGD liquor and bulkmore » solid byproducts for separate disposal. The project is conducting pilot- and full-scale tests of the additives in wet FGD absorbers. The tests are intended to determine required additive dosages to prevent Hg{sup 0} re-emissions and to separate mercury from the normal FGD byproducts for three coal types: Texas lignite/Powder River Basin (PRB) coal blend, high-sulfur Eastern bituminous coal, and low-sulfur Eastern bituminous coal. The project team consists of URS Group, Inc., EPRI, Luminant Power (was TXU Generation Company LP), Southern Company, IPL (an AES company), Evonik Degussa Corporation and the Nalco Company. Luminant Power has provided the Texas lignite/PRB co-fired test site for pilot FGD tests and cost sharing. Southern Company has provided the low-sulfur Eastern bituminous coal host site for wet scrubbing tests, as well as the pilot- and full-scale jet bubbling reactor (JBR) FGD systems tested. IPL provided the high-sulfur Eastern bituminous coal full-scale FGD test site and cost sharing. Evonik Degussa Corporation is providing the TMT-15 additive, and the Nalco Company is providing the Nalco 8034 additive. Both companies are also supplying technical support to the test program as in-kind cost sharing. The project is being conducted in six tasks. Of the six project tasks, Task 1 involves project planning and Task 6 involves management and reporting. The other four tasks involve field testing on FGD systems, either at pilot or full scale. The four tasks include: Task 2 - Pilot Additive Testing in Texas Lignite Flue Gas; Task 3 - Full-scale FGD Additive Testing in High-sulfur Eastern Bituminous Flue Gas; Task 4 - Pilot Wet Scrubber Additive Tests at Plant Yates; and Task 5 - Full-scale Additive Tests at Plant Yates. The pilot-scale tests and the full-scale test using high-sulfur coal were completed in 2005 and 2006 and have been previously reported. This topical report presents the results from the Task 5 full-scale additive tests, conducted at Southern Company's Plant Yates Unit 1. Both additives were tested there.« less

Field Testing of a Wet FGD Additive for Enhanced Mercury Control - Task 3 Full-scale Test Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gary Blythe

2007-05-01

This Topical Report summarizes progress on Cooperative Agreement DE-FC26-04NT42309, 'Field Testing of a Wet FGD Additive'. The objective of the project is to demonstrate the use of a flue gas desulfurization (FGD) additive, Degussa Corporation's TMT-15, to prevent the reemission of elemental mercury (Hg{sup 0}) in flue gas exiting wet FGD systems on coal-fired boilers. Furthermore, the project intends to demonstrate whether the additive can be used to precipitate most of the mercury (Hg) removed in the wet FGD system as a fine TMT salt that can be separated from the FGD liquor and bulk solid byproducts for separate disposal.more » The project is conducting pilot- and full-scale tests of the TMT-15 additive in wet FGD absorbers. The tests are intended to determine required additive dosages to prevent Hg{sup 0} reemissions and to separate mercury from the normal FGD byproducts for three coal types: Texas lignite/Power River Basin (PRB) coal blend, high-sulfur Eastern bituminous coal, and low-sulfur Eastern bituminous coal. The project team consists of URS Group, Inc., EPRI, TXU Generation Company LP, Southern Company, and Degussa Corporation. TXU Generation has provided the Texas lignite/PRB cofired test site for pilot FGD tests, Monticello Steam Electric Station Unit 3. Southern Company is providing the low-sulfur Eastern bituminous coal host site for wet scrubbing tests, as well as the pilot- and full-scale jet bubbling reactor (JBR) FGD systems to be tested. IPL, an AES company, provided the high-sulfur Eastern bituminous coal full-scale FGD test site and cost sharing. Degussa Corporation is providing the TMT-15 additive and technical support to the test program as cost sharing. The project is being conducted in six tasks. Of the six project tasks, Task 1 involves project planning and Task 6 involves management and reporting. The other four tasks involve field testing on FGD systems, either at pilot or full scale. The four tasks include: Task 2 - Pilot Additive Testing in Texas Lignite Flue Gas; Task 3 - Full-scale FGD Additive Testing in High-sulfur Eastern Bituminous Flue Gas; Task 4 - Pilot Wet Scrubber Additive Tests at Plant Yates; and Task 5 - Full-scale Additive Tests at Plant Yates. The pilot-scale tests were completed in 2005 and have been previously reported. This topical report presents the results from the Task 3 full-scale additive tests, conducted at IPL's Petersburg Station Unit 2. The Task 5 full-scale additive tests will be conducted later in calendar year 2007.« less

Fighter pilots' heart rate, heart rate variation and performance during an instrument flight rules proficiency test.

PubMed

Mansikka, Heikki; Virtanen, Kai; Harris, Don; Simola, Petteri

2016-09-01

Increased task demand will increase the pilot mental workload (PMWL). When PMWL is increased, mental overload may occur resulting in degraded performance. During pilots' instrument flight rules (IFR) proficiency test, PMWL is typically not measured. Therefore, little is known about workload during the proficiency test and pilots' potential to cope with higher task demands than those experienced during the test. In this study, fighter pilots' performance and PMWL was measured during a real IFR proficiency test in an F/A-18 simulator. PMWL was measured using heart rate (HR) and heart rate variation (HRV). Performance was rated using Finnish Air Force's official rating scales. Results indicated that HR and HRV differentiate varying task demands in situations where variations in performance are insignificant. It was concluded that during a proficiency test, PMWL should be measured together with the task performance measurement. Copyright © 2016 Elsevier Ltd. All rights reserved.

Latent Profile Analyses of Test Anxiety: A Pilot Study

ERIC Educational Resources Information Center

von der Embse, Nathaniel P.; Mata, Andrea D.; Segool, Natasha; Scott, Emma-Catherine

2014-01-01

In an era of test-based accountability, there has been a renewed interest in understanding the relationship between test anxiety and test performance. The development and validation of test anxiety scales have grown with the rise of test anxiety research. Research is needed to critically examine the psychometric properties of these scales prior to…

Primary Childhood School Success Scale.

ERIC Educational Resources Information Center

Seagraves, Margaret C.

The purpose of this research study was to build and pilot a psychometric instrument, the Primary Childhood School Success Scale (PCSSS), to identify behaviors needed for children to be successful in first grade. Fifty-two teacher responses were collected. The instrument had a reliability coefficient (Alpha) of 0.95, a mean of 13.26, and a variance…

Defining Feasibility and Pilot Studies in Preparation for Randomised Controlled Trials: Development of a Conceptual Framework

PubMed Central

Eldridge, Sandra M.; Lancaster, Gillian A.; Campbell, Michael J.; Thabane, Lehana; Hopewell, Sally; Coleman, Claire L.; Bond, Christine M.

2016-01-01

We describe a framework for defining pilot and feasibility studies focusing on studies conducted in preparation for a randomised controlled trial. To develop the framework, we undertook a Delphi survey; ran an open meeting at a trial methodology conference; conducted a review of definitions outside the health research context; consulted experts at an international consensus meeting; and reviewed 27 empirical pilot or feasibility studies. We initially adopted mutually exclusive definitions of pilot and feasibility studies. However, some Delphi survey respondents and the majority of open meeting attendees disagreed with the idea of mutually exclusive definitions. Their viewpoint was supported by definitions outside the health research context, the use of the terms ‘pilot’ and ‘feasibility’ in the literature, and participants at the international consensus meeting. In our framework, pilot studies are a subset of feasibility studies, rather than the two being mutually exclusive. A feasibility study asks whether something can be done, should we proceed with it, and if so, how. A pilot study asks the same questions but also has a specific design feature: in a pilot study a future study, or part of a future study, is conducted on a smaller scale. We suggest that to facilitate their identification, these studies should be clearly identified using the terms ‘feasibility’ or ‘pilot’ as appropriate. This should include feasibility studies that are largely qualitative; we found these difficult to identify in electronic searches because researchers rarely used the term ‘feasibility’ in the title or abstract of such studies. Investigators should also report appropriate objectives and methods related to feasibility; and give clear confirmation that their study is in preparation for a future randomised controlled trial designed to assess the effect of an intervention. PMID:26978655

Scaling-up Fermentation of Pichia pastoris to demonstration-scale using new methanol-feeding strategy and increased air pressure instead of pure oxygen supplement

PubMed Central

Liu, Wan-Cang; Gong, Ting; Wang, Qing-Hua; Liang, Xiao; Chen, Jing-Jing; Zhu, Ping

2016-01-01

Scaling-up of high-cell-density fermentation (HCDF) of Pichia pastoris from the lab or pilot scale to the demonstration scale possesses great significance because the latter is the final technological hurdle in the decision to go commercial. However, related investigations have rarely been reported. In this paper, we study the scaling-up processes of a recombinant P. pastoris from the pilot (10 to 100-L) to the demonstration (1,000-L) scales, which can be used to convert 7-β-xylosyl-10-deacetyltaxol into 10-deacetyltaxol by the β-xylosidase for semi-synthesis of Taxol. We demonstrated that a pure oxygen supplement can be omitted from the HCDF if the super atmospheric pressure was increased from 0.05 to 0.10 ± 0.05 MPa, and we developed a new methanol feeding biomass-stat strategy (0.035 mL/g/h) with 1% dissolved oxygen and 100 g/L initial induction biomass (dry cell weight). The scaling-up was reproducible, and the best results were obtained from the 1,000-L scale, featuring a shorter induction time and the highest enzyme activities and productions, respectively. The specific growth and specific production rates were also determined. This study lays a solid foundation for the commercial preparation of 10-deacetyltaxol through the recombinant yeast. It also provides a successful paradigm for scaling-up HCDF of P. pastoris to the demonstration scale. PMID:26790977

Existing Whole-House Solutions Case Study: Pilot Demonstration of Phased Retrofits in Florida Homes - Central and South Florida Homes

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2014-08-01

In this pilot project, the Building America Partnership for Improved Residential Construction and Florida Power and Light are collaborating to retrofit a large number of homes using a phased approach to both simple and deep retrofits. This project will provide the information necessary to significantly reduce energy use through larger community-scale projects in collaboration with utilities, program administrators and other market leader stakeholders.

TECHNOLOGY EVALUATION REPORT, SITE PROGRAM DEMONSTRATION TEST: SHIRCO PILOT-SCALE INFRARED INCINERATION SYSTEM ROSE TOWNSHIP DEMODE ROAD SUPERFUND SITE - VOLUME II

EPA Science Inventory

The performance of the Shirco pilot-scale infrared thermal destruction system has been evaluated at the Rose Township, Demode Road Superfund Site and is presented in the report. The waste tested consisted of solvents, organics and heavy metals in an illegal dump site. Volume I gi...

Amyris, Inc. Integrated Biorefinery Project Summary Final Report - Public Version

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gray, David; Sato, Suzanne; Garcia, Fernando

The Amyris pilot-scale Integrated Biorefinery (IBR) leveraged Amyris synthetic biology and process technology experience to upgrade Amyris’s existing Emeryville, California pilot plant and fermentation labs to enable development of US-based production capabilities for renewable diesel fuel and alternative chemical products. These products were derived semi-synthetically from high-impact biomass feedstocks via microbial fermentation to the 15-carbon intermediate farnesene, with subsequent chemical finishing to farnesane. The Amyris IBR team tested and provided methods for production of diesel and alternative chemical products from sweet sorghum, and other high-impact lignocellulosic feedstocks, at pilot scale. This enabled robust techno-economic analysis (TEA), regulatory approvals, and amore » basis for full-scale manufacturing processes and facility design.« less

Assessment of Crew Workload for the RAH-66 Comanche Force Development Experiment 1

DTIC Science & Technology

2001-10-01

Scale and a cockpit controls and displays usability questionnaire . Results of the assessment indicate that (a) workload was tolerable for the pilots...Workload Levels Between Front Seat and Back Seat 13 3.4 Pilot Responses to Controls and Displays Usability Questionnaire 13 3.5 HMD Symbology 13 4... questionnaire . The data were analyzed to determine if the pilot flying the aircraft (pilot on controls) and the pilot operating the mission equipment

Conceptual design of a lunar oxygen pilot plant Lunar Base Systems Study (LBSS) task 4.2

NASA Technical Reports Server (NTRS)

1988-01-01

The primary objective was to develop conceptual designs of two pilot plants to produce oxygen from lunar materials. A lunar pilot plant will be used to generate engineering data necessary to support an optimum design of a larger scale production plant. Lunar oxygen would be of primary value as spacecraft propellant oxidizer. In addition, lunar oxygen would be useful for servicing nonregenerative fuel cell power systems, providing requirements for life support, and to make up oxygen losses from leakage and airlock cycling. Thirteen different lunar oxygen production methods are described. Hydrogen reduction of ilmenite and extraction of solar-wind hydrogen from bulk lunar soil were selected for conceptual design studies. Trades and sensitivity analyses were performed with these models.

Photocatalytic treatment of an industrial effluent using artificial and solar UV radiation: an operational cost study on a pilot plant scale.

PubMed

Durán, A; Monteagudo, J M; San Martín, I

2012-05-15

The aim of this work was to study the operation costs of treating a real effluent from an integrated gasification combined cycle (IGCC) power station located in Spain. The study compares different homogeneous photocatalytic processes on a pilot plant scale using different types of radiation (artificial UV or solar UV with a compound parabolic collector). The efficiency of the processes was evaluated by an analysis of the total organic carbon (TOC) removed. The following processes were considered in the study: (i) a photo-Fenton process at an artificial UV pilot plant (with the initial addition of H(2)O(2)), (ii) a modified photo-Fenton process with continuous addition of H(2)O(2) and O(2) to the system and (iii) a ferrioxalate-assisted solar photo-Fenton process at a compound parabolic collector (CPC) pilot plant. The efficiency of these processes in degrading pollutants has been studied previously, and the results obtained in each of those studies have been published elsewhere. The operational costs due to the consumption of electrical energy, reagents and catalysts were calculated from the optimal conditions of each process. The results showed that the solar photo-Fenton system was economically feasible, being able to achieve up to 75% mineralization with a total cost of 6 €/m(3), which can be reduced to 3.6 €/m(3) by subtracting the electrical costs because the IGCC plant is self-sufficient in terms of energy. Copyright © 2011 Elsevier Ltd. All rights reserved.

A pilot study exploring the relationship between lifelong learning and factors associated with evidence-based medicine.

PubMed

Mi, Misa; Halalau, Alexandra

2016-07-03

To explore possible relationships between residents' lifelong learning orientation, skills in practicing evidence-based medicine (EBM), and perceptions of the environment for learning and practicing EBM. This was a pilot study with a cross-sectional survey design. Out of 60 residents in a medical residency program, 29 participated in the study. Data were collected using a survey that comprised three sections: the JeffSPLL Scale, EBM Environment Scale, and an EBM skill questionnaire. Data were analyzed using SPSS and were reported with descriptive and inferential statistics (mean, standard deviation, Pearson's correlation, and a two-sample t-test). Mean scores on the JeffSPLL Scale were significantly correlated with perceptions of the EBM Scale and use of EBM resources to keep up to date or solve a specific patient care problem. There was a significant correlation between mean scores on the EBM Scale and hours per week spent in reading medical literature to solve a patient care problem. Two-sample t-tests show that residents with previous training in research methods had significantly higher scores on the JeffSPLL Scale (p=0.04), EBM Scale (p=0.006), and self-efficacy scale (p =0.024). Given the fact that physicians are expected to be lifelong learners over the course of their professional career, developing residents' EBM skills and creating interventions to improve specific areas in the EBM environment would likely foster residents' lifelong learning orientation.

Manufacturing of High-Concentration Monoclonal Antibody Formulations via Spray Drying-the Road to Manufacturing Scale.

PubMed

Gikanga, Benson; Turok, Robert; Hui, Ada; Bowen, Mayumi; Stauch, Oliver B; Maa, Yuh-Fun

2015-01-01

Spray-dried monoclonal antibody (mAb) powders may offer applications more versatile than the freeze-dried cake, including preparing high-concentration formulations for subcutaneous administration. Published studies on this topic, however, are generally scarce. This study evaluates a pilot-scale spray dryer against a laboratory-scale dryer to spray-dry multiple mAbs in consideration of scale-up, impact on mAb stability, and feasibility of a high-concentration preparation. Under similar conditions, both dryers produced powders of similar properties-for example, water content, particle size and morphology, and mAb stability profile-despite a 4-fold faster output by the pilot-scale unit. All formulations containing arginine salt or a combination of arginine salt and trehalose were able to be spray-dried with high powder collection efficiency (>95%), but yield was adversely affected in formulations with high trehalose content due to powder sticking to the drying chamber. Spray-drying production output was dictated by the size of the dryer operated at an optimal liquid feed rate. Spray-dried powders could be reconstituted to high-viscosity liquids, >300 cP, substantially beyond what an ultrafiltration process can achieve. The molar ratio of trehalose to mAb needed to be reduced to 50:1 in consideration of isotonicity of the formulation with mAb concentration at 250 mg/mL. Even with this low level of sugar protection, long-term stability of spray-dried formulations remained superior to their liquid counterparts based on size variant and potency data. This study offers a commercially viable spray-drying process for biological bulk storage and an option for high-concentration mAb manufacturing. This study evaluates a pilot-scale spray dryer against a laboratory-scale dryer to spray-dry multiple monoclonal antibodies (mAbs) from the perspective of scale-up, impact on mAb stability, and feasibility of a high-concentration preparation. The data demonstrated that there is no process limitation in solution viscosity when high-concentration mAb formulations are prepared from spray-dried powder reconstitution compared with concentration via the conventional ultrafiltration process. This study offers a commercially viable spray-drying process for biological bulk storage and a high-concentration mAb manufacturing option for subcutaneous administration. The outcomes of this study will benefit scientists and engineers who develop high-concentration mAb products by providing a viable manufacturing alternative. © PDA, Inc. 2015.

Pilot Study: Survey Tools for Assessing Parenting Styles and Family Contributors to the Development of Obesity in Arab Children Ages 6 to 12 Years.

PubMed

Tami, Suzan H; Reed, Debra B; Trejos, Elizabeth; Boylan, Mallory; Wang, Shu

2015-11-05

Our pilot study was conducted to test the reliability of the Caregiver's Feeding Styles Questionnaire (CFSQ) and the Family Nutrition and Physical Activity Assessment (FNPA) in a sample of Arab mothers. Twenty-five Arab mothers completed the CFSQ, FNPA, and the Participant Background Survey for the first administration. After 1-2 weeks, participants completed the CFSQ and the FNPA for the second administration. The two administrations of the surveys allowed for test/retest reliability of the CFSQ and the FNPA and to measure the internal consistency of the two surveys. Pearson's correlation between the first and second administrations or the 19-item scale (demandingness) and the 7-item scale (responsiveness) of the CFSQ were .95 and .86, respectively. As for the FNPA, Pearson's correlation was .80. The estimated reliabilities (Cronbach's alpha) of the CFSQ increased from .86 for the first administration to .93 for the second administration. However, the estimated reliabilities of the FNPA slightly increased from .58 for first administration to .59 for the second administration. In our pilot study of Arab mothers, the CFSQ and FNPA were shown to be promising in terms of reliability and content validity.

Measuring mental workload and physiological reactions in marine pilots: Building bridges towards redlines of performance.

PubMed

Orlandi, Luca; Brooks, Benjamin

2018-05-01

This paper investigates the effects of shiphandling manoeuvres on mental workload and physiological reactions in ten marine pilots. Each pilot performed four berthings in a ship simulator. Those berthings were differentiated by two factors, level of difficulty and familiarity with the port. Each berthing could also be divided into five phases, three during the execution and two resting periods, one before and one after the execution (dedicated to baseline physiological data collection). Mental workload was measured through two self assessment scales: the NASA TLX and a Likert scale. Power spectral densities on Beta bands 1 and 2 were obtained from EEG. Heart rate and heart rate variability were obtained from ECG. Pupil dilation was obtained from eye tracking. Workload levels were higher as berthings increased in difficulty level and/or the pilots completed the berthings in unfamiliar ports. Responses differed across specific phases of the berthings. Physiological responses could indirectly monitor levels of mental workload, and could be adopted in future applications to evaluate training improvements and performance. This study provides an example of an applied methodology aiming to define an upper redline of task demands in the context of marine pilotage. Copyright © 2018. Published by Elsevier Ltd.

Brief Report: An Observational Measure of Empathy for Autism Spectrum--A Preliminary Study of the Development and Reliability of the Client Emotional Processing Scale

ERIC Educational Resources Information Center

Robinson, Anna; Elliott, Robert

2016-01-01

People with autism spectrum disorder (ASD), can have difficulties in emotion processing, including recognising their own and others' emotions, leading to problems in emotion regulation and interpersonal relating. This study reports the development and piloting of the Client Emotional Processing Scale-Autism Spectrum (CEPS-AS), a new observer…

Initial Development of a Cultural Values and Beliefs Scale among Dakota/Nakota/Lakota People: A Pilot Study

ERIC Educational Resources Information Center

Reynolds, W. Rusty; Quevillon, Randal P.; Boyd, Beth; Mackey, Duane

2006-01-01

This study was the initial phase in the development of a mental health assessment tool. The Native American Cultural Values and Beliefs Scale is a 12-item instrument that assesses three dimensions of American Indian/Alaska Native values and beliefs: 1) the importance, 2) the frequency of practicing, and 3) the amount of distress caused by not…

Calibration and verification of models of organic carbon removal kinetics in Aerated Submerged Fixed-Bed Biofilm Reactors (ASFBBR): a case study of wastewater from an oil-refinery.

PubMed

Trojanowicz, Karol; Wójcik, Włodzimierz

2011-01-01

The article presents a case-study on the calibration and verification of mathematical models of organic carbon removal kinetics in biofilm. The chosen Harremöes and Wanner & Reichert models were calibrated with a set of model parameters obtained both during dedicated studies conducted at pilot- and lab-scales for petrochemical wastewater conditions and from the literature. Next, the models were successfully verified through studies carried out utilizing a pilot ASFBBR type bioreactor installed in an oil-refinery wastewater treatment plant. During verification the pilot biofilm reactor worked under varying surface organic loading rates (SOL), dissolved oxygen concentrations and temperatures. The verification proved that the models can be applied in practice to petrochemical wastewater treatment engineering for e.g. biofilm bioreactor dimensioning.

PILOT PEAT-BED TREATMENT SYSTEM FOR NPDES OUTFALL H-12

DOE Office of Scientific and Technical Information (OSTI.GOV)

Halverson, N; Ralph Nichols, R; Topher Berry, T

2007-10-22

A National Pollutant Discharge Elimination System (NPDES) Permit was issued to the Savannah River Site (SRS) by the South Carolina Department of Health and Environmental Control (SCDHEC) and became effective on December 1, 2003. The new permit contained revised limits for copper and zinc derived by adjusting the South Carolina aquatic life water quality standards in accordance with dissolved metals criteria. The new copper and zinc limits are very low and may not be met consistently at Outfall H-12. The outfall has periodically exceeded the new 6 {micro}g/l (0.006 mg/L) monthly average limit and the 8 {micro}g/l (0.008 mg/L) maximummore » limit for copper and recently has begun exceeding the 100 {micro}g/l (0.100 mg/L) limit for zinc. The compliance date for Outfall H-12 is November 1, 2008. A study was conducted on this outfall and other outfalls to evaluate possible alternatives for meeting the new permit limits (Shipman and Bugher 2004). The study team recommended construction of a peat bed for treatment of the Outfall H-12 effluent. This recommendation was repeated by a second alternatives study team in 2007 (WSRC 2007). A bench-scale laboratory study demonstrated the feasibility of peat-bed treatment for Outfall H-12 effluent, with the peat demonstrating excellent removal of copper (Nelson and Specht 2005). An additional study was performed in 2006 and early 2007 using vertical-flow peat columns to investigate the influence of water retention time (contact time) on the removal of copper and zinc from the water (Nelson 2007c). Analytical results indicated that copper removal was very high at each of the three retention times tested, ranging from 99.6% removal at five and three hours to 98.8% removal at one hour. Effluent copper levels from these studies were much lower than the new compliance limit for the outfall. Most divalent metals, including zinc, were removed to below their normal reporting detection limit. The H-Area Material Disposition organization requested a larger-scale study to investigate key design and operation parameters/issues, such as the possibility of rapid plugging of the piping or clogging of the peat bed, the effectiveness of the treatment, hydraulic conductivity, etc. The resulting pilot-scale facility was constructed adjacent to Outfall H-12 with SCDHEC approval (Mullinax 2007). The pilot-scale study was performed by the Savannah River National Laboratory's (SRNL) Environmental Science and Biotechnology Directorate personnel. Since the construction and operation of the pilot-scale peat bed facility, however, a new strategy for achieving compliance of Outfall H-12 effluent with the new permit limits has been selected. This new strategy incorporates a variety of efforts including source reduction, recalculation of limits using an aquatic species that is indigenous to the area instead of a standard species, and dissolved organic carbon addition to reduce copper toxicity. This report documents the construction and operation of the pilot-scale treatment system, the results obtained, and recommendations on the usefulness of this technology for Outfall H-12 or other outfalls at SRS.« less

Fermentative lactic acid production from coffee pulp hydrolysate using Bacillus coagulans at laboratory and pilot scales.

PubMed

Pleissner, Daniel; Neu, Anna-Katrin; Mehlmann, Kerstin; Schneider, Roland; Puerta-Quintero, Gloria Inés; Venus, Joachim

2016-10-01

In this study, the lignocellulosic residue coffee pulp was used as carbon source in fermentative l(+)-lactic acid production using Bacillus coagulans. After thermo-chemical treatment at 121°C for 30min in presence of 0.18molL(-1) H2SO4 and following an enzymatic digestion using Accellerase 1500 carbon-rich hydrolysates were obtained. Two different coffee pulp materials with comparable biomass composition were used, but sugar concentrations in hydrolysates showed variations. The primary sugars were (gL(-1)) glucose (20-30), xylose (15-25), sucrose (5-11) and arabinose (0.7-10). Fermentations were carried out at laboratory (2L) and pilot (50L) scales in presence of 10gL(-1) yeast extract. At pilot scale carbon utilization and lactic acid yield per gram of sugar consumed were 94.65% and 0.78gg(-1), respectively. The productivity was 4.02gL(-1)h(-1). Downstream processing resulted in a pure formulation containing 937gL(-1)l(+)-lactic acid with an optical purity of 99.7%. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

Anaerobic Digestion of Laminaria japonica Waste from Industrial Production Residues in Laboratory- and Pilot-Scale.

PubMed

Barbot, Yann Nicolas; Thomsen, Claudia; Thomsen, Laurenz; Benz, Roland

2015-09-18

The cultivation of macroalgae to supply the biofuel, pharmaceutical or food industries generates a considerable amount of organic residue, which represents a potential substrate for biomethanation. Its use optimizes the total resource exploitation by the simultaneous disposal of waste biomaterials. In this study, we explored the biochemical methane potential (BMP) and biomethane recovery of industrial Laminaria japonica waste (LJW) in batch, continuous laboratory and pilot-scale trials. Thermo-acidic pretreatment with industry-grade HCl or industrial flue gas condensate (FGC), as well as a co-digestion approach with maize silage (MS) did not improve the biomethane recovery. BMPs between 172 mL and 214 mL g(-1) volatile solids (VS) were recorded. We proved the feasibility of long-term continuous anaerobic digestion with LJW as sole feedstock showing a steady biomethane production rate of 173 mL g(-1) VS. The quality of fermentation residue was sufficient to serve as biofertilizer, with enriched amounts of potassium, sulfur and iron. We further demonstrated the upscaling feasibility of the process in a pilot-scale system where a CH₄ recovery of 189 L kg(-1) VS was achieved and a biogas composition of 55% CH₄ and 38% CO₂ was recorded.

Cultivation of Chlorella vulgaris in a pilot-scale photobioreactor using real centrate wastewater with waste glycerol for improving microalgae biomass production and wastewater nutrients removal.

PubMed

Ren, Hongyan; Tuo, Jinhua; Addy, Min M; Zhang, Renchuan; Lu, Qian; Anderson, Erik; Chen, Paul; Ruan, Roger

2017-12-01

To improve nutrients removal from real centrate wastewater and enhance the microalgae biomass production, cultivation of Chlorella vulgaris in lab and a pilot-scale photobioreactor with waste glycerol was studied. The results showed the optimal concentration of the crude glycerol was 1.0gL -1 with the maximum biomass productivity of 460mgL -1 d -1 TVS, the maximum lipid content of 27%, the nutrient removal efficiency of all above 86%, due to more balanced C/N ratio. The synergistic relationship between the wastewater-borne bacteria and the microalgae had significant good influence on nutrient removal. In pilot-scale wastewater-based algae cultivation, with 1gL -1 waste glycerol addition, the average biomass production of 16.7gm -2 d -1 , lipid content of 23.6%, and the removal of 2.4gm -2 d -1 NH 4 + -N, 2.7gm -2 d -1 total nitrogen, 3.0gm -2 d -1 total phosphorous, and 103.0gm -2 d -1 of COD were attained for 34days semi-continuous mode. Copyright © 2017 Elsevier Ltd. All rights reserved.

Acute spinal injury after centrifuge training in asymptomatic fighter pilots.

PubMed

Kang, Kyung-Wook; Shin, Young Ho; Kang, Seungcheol

2015-04-01

Many countries have hypergravity training centers using centrifuges for pilots to cope with a high gravity (G) environment. The high G training carries potential risk for the development of spinal injury. However, no studies evaluated the influence of centrifuge training on the spines of asymptomatic fighter pilots on a large scale. Study subjects were 991 male fighter pilots with high G training at one institution. Subject variables included information about physical characteristics, flight hours of pilots prior to the training, and G force exposure related factors during training. The two dependent variables were whether the pilots developed acute spinal injury after training and the severity of the injury (major/minor). The incidence of acute spinal injury after high G training was 2.3% (23 of 991 subjects). There were 19 subjects who developed minor injury and 4 subjects who developed a herniated intervertebral disc, which is considered a major injury. In multivariate analysis, only the magnitude of G force during training was significantly related to the development of acute spinal injury. However, there was no significant factor related to the severity of the injury. These results suggest that high G training could cause negative effects on fighter pilots' spines. The magnitude of G force during training seemed to be the most significant factor affecting the occurrence of acute spinal injury.

A randomized controlled pilot study of the effectiveness of occupational therapy for children with sensory modulation disorder.

PubMed

Miller, Lucy Jane; Coll, Joseph R; Schoen, Sarah A

2007-01-01

A pilot randomized controlled trial (RCT) of the effectiveness of occupational therapy using a sensory integration approach (OT-SI) was conducted with children who had sensory modulation disorders (SMDs). This study evaluated the effectiveness of three treatment groups. In addition, sample size estimates for a large scale, multisite RCT were calculated. Twenty-four children with SMD were randomly assigned to one of three treatment conditions; OT-SI, Activity Protocol, and No Treatment. Pretest and posttest measures of behavior, sensory and adaptive functioning, and physiology were administered. The OT-SI group, compared to the other two groups, made significant gains on goal attainment scaling and on the Attention subtest and the Cognitive/Social composite of the Leiter International Performance Scale-Revised. Compared to the control groups, OT-SI improvement trends on the Short Sensory Profile, Child Behavior Checklist, and electrodermal reactivity were in the hypothesized direction. Findings suggest that OT-SI may be effective in ameliorating difficulties of children with SMD.

The Association between Generalized Anxiety Disorder, Subthreshold Anxiety Symptoms and Fear of Falling among Older Adults: Preliminary Results from a Pilot Study.

PubMed

Payette, Marie-Christine; Bélanger, Claude; Benyebdri, Fethia; Filiatrault, Johanne; Bherer, Louis; Bertrand, Josie-Anne; Nadeau, Alexandra; Bruneau, Marie-Andrée; Clerc, Doris; Saint-Martin, Monique; Cruz-Santiago, Diana; Ménard, Caroline; Nguyen, Philippe; Vu, T T Minh; Comte, Francis; Bobeuf, Florian; Grenier, Sébastien

2017-01-01

A relationship between generalized anxiety disorder (GAD) and fear of falling (FOF) has long been proposed but never specifically studied. This study aimed at analyzing the relationship between FOF and GAD or anxiety symptoms, while controlling for major depressive episodes (MDE), depressive symptoms, fall risk, and sociodemographic variables. Twenty-five older adults participated in this pilot study. Assessments included the following: Anxiety Disorder Interview Schedule, Geriatric Anxiety Inventory, Geriatric Depression Scale, Falls-Efficacy Scale-International. A multidisciplinary team evaluated fall risk. FOF was significantly correlated with GAD, MDE, anxiety and depressive symptoms, and fall risk, but not with sociodemographic variables. Multiple regression analyses indicated that GAD and anxiety symptoms were significantly and independently associated with FOF. Although the results of this pilot study should be replicated with larger samples, they suggest that FOF is associated with GAD and anxiety symptoms even when considering physical factors that increase the risk of falling. Treatment of FOF in patients with GAD may present a particular challenge because of the central role of intolerance of uncertainty, which may prevent patients from regaining confidence despite the reduction of fall risk. Clinicians should screen for GAD and anxiety symptoms in patients with FOF to improve detection and treatment.

Adapting, piloting and evaluating complex public health interventions: lessons learned from the Nurse–Family Partnership in Canadian public health settings

PubMed Central

Jack, S. M.; Catherine, N.; Gonzalez, A.; MacMillan, H. L.; Sheehan, D.; Waddell, C.

2015-01-01

Abstract Introduction: The Nurse–Family Partnership (NFP) is a home-visit program for young and first-time, socially and economically disadvantaged mothers. Evidence from three United States randomized controlled trials (RCTs) on the effectiveness of this intervention at improving pregnancy outcomes, improving child health and development, and increasing maternal economic self-sufficiency is robust. However, the effectiveness of the NFP in Canada, with its different health and social care context, needs to be determined. The purpose of this article is to describe the complex process for moving the NFP from the research arena to full implementation in Canada. Methods: This process of evaluation in Canada includes (1) adapting the intervention; (2) piloting the intervention in small-scale feasibility and acceptability studies; and (3) conducting an RCT and process evaluation through a study called the British Columbia Healthy Connections Project (BCHCP). This large-scale evaluation also creates an opportunity to expand the NFP evidence base by conducting an additional study to examine potential biological mechanisms linking intervention and behavioural outcomes in children. Results: Adaptation of the NFP home-visit materials is a continuous process. A pilot project determined that it was feasible to enrol eligible women into the NFP. This pilot also determined that, in Canada, it was most appropriate for public health agencies to implement the NFP and for public health nurses to deliver the intervention. Finally, the pilot showed that this intensive home-visit program was acceptable to clients, their family members and health care providers. Through the BCHCP, the next steps—the RCT and process evaluation—are currently underway. The BCHCP will also set the foundation for long-term evaluation of key public health outcomes in a highly vulnerable population of families. PMID:26605564

Adapting, piloting and evaluating complex public health interventions: lessons learned from the Nurse-Family Partnership in Canadian public health settings.

PubMed

Jack, S M; Catherine, N; Gonzalez, A; MacMillan, H L; Sheehan, D; Waddell, D

2015-01-01

The Nurse-Family Partnership (NFP) is a home-visit program for young and first-time, socially and economically disadvantaged mothers. Evidence from three United States randomized controlled trials (RCTs) on the effectiveness of this intervention at improving pregnancy outcomes, improving child health and development, and increasing maternal economic self-sufficiency is robust. However, the effectiveness of the NFP in Canada, with its different health and social care context, needs to be determined. The purpose of this article is to describe the complex process for moving the NFP from the research arena to full implementation in Canada. This process of evaluation in Canada includes (1) adapting the intervention; (2) piloting the intervention in small-scale feasibility and acceptability studies; and (3) conducting an RCT and process evaluation through a study called the British Columbia Healthy Connections Project (BCHCP). This large-scale evaluation also creates an opportunity to expand the NFP evidence base by conducting an additional study to examine potential biological mechanisms linking intervention and behavioural outcomes in children. Adaptation of the NFP home-visit materials is a continuous process. A pilot project determined that it was feasible to enrol eligible women into the NFP. This pilot also determined that, in Canada, it was most appropriate for public health agencies to implement the NFP and for public health nurses to deliver the intervention. Finally, the pilot showed that this intensive home-visit program was acceptable to clients, their family members and health care providers. Through the BCHCP, the next steps - the RCT and process evaluation - are currently underway. The BCHCP will also set the foundation for long-term evaluation of key public health outcomes in a highly vulnerable population of families.

Instrument development and validation of a quality scale for historical research papers (QSHRP): a pilot study.

PubMed

Kelly, Jacinta; Watson, Roger

2014-12-01

To report a pilot study for the development and validation of an instrument to measure quality in historical research papers. There are no set criteria to assess historical papers published in nursing journals. A three phase mixed method sequential confirmatory design. In 2012, we used a three-phase approach to item generation and content evaluation. In phase 1, we consulted nursing historians using an online survey comprising three open-ended questions and revised the items. In phase 2, we evaluated the revised items for relevance with expert historians using a 4-point Likert scale and Content Validity Index calculation. In phase 3, we conducted reliability testing of the instrument using a 3-point Likert scale. In phase 1, 121 responses were generated via the online survey and revised to 40 interrogatively phrased items. In phase 2, five items with an Item Content Validity Index score of ≥0·7 remained. In phase 3, responses from historians resulted in 100% agreement to questions 1, 2 and 4 and 89% and 78%, respectively, to questions 3 and 5. Items for the QSHRP have been identified, content validated and reliability tested. This scale improves on previous scales, which over-emphasized source criticism. However, a full-scale study is needed with nursing historians to increase its robustness. © 2014 John Wiley & Sons Ltd.

Implicit theories of writing and their impact on students' response to a SRSD intervention.

PubMed

Limpo, Teresa; Alves, Rui A

2014-12-01

In the field of intelligence research, it has been shown that some people conceive intelligence as a fixed trait that cannot be changed (entity beliefs), whereas others conceive it as a malleable trait that can be developed (incremental beliefs). What about writing? Do people hold similar implicit theories about the nature of their writing ability? Furthermore, are these beliefs likely to influence students' response to a writing intervention? We aimed to develop a scale to measure students' implicit theories of writing (pilot study) and to test whether these beliefs influence strategy-instruction effectiveness (intervention study). In the pilot and intervention studies participated, respectively, 128 and 192 students (Grades 5-6). Based on existing instruments that measure self-theories of intelligence, we developed the Implicit Theories of Writing (ITW) scale that was tested with the pilot sample. In the intervention study, 109 students received planning instruction based on the self-regulated strategy development model, whereas 83 students received standard writing instruction. Students were evaluated before, in the middle, and after instruction. ITW's validity was supported by piloting results and their successful cross-validation in the intervention study. In this, intervention students wrote longer and better texts than control students. Moreover, latent growth curve modelling showed that the more the intervention students conceived writing as a malleable skill, the more the quality of their texts improved. This research is of educational relevance because it provides a measure to evaluate students' implicit theories of writing and shows their impact on response to intervention. © 2014 The British Psychological Society.

Mental workload in decision and control

NASA Technical Reports Server (NTRS)

Sheridan, T. B.

1979-01-01

This paper briefly reviews the problems of defining and measuring the 'mental workload' of aircraft pilots and other human operators of complex dynamic systems. Of the alternative approaches the author indicates a clear preference for the use of subjective scaling. Some recent experiments from MIT and elsewhere are described which utilize subjective mental workload scales in conjunction with human decision and control tasks in the laboratory. Finally a new three-dimensional mental workload rating scale, under current development for use by IFR aircraft pilots, is presented.

Effect of thermal hydrolysis and ultrasounds pretreatments on foaming in anaerobic digesters.

PubMed

Alfaro, N; Cano, R; Fdz-Polanco, F

2014-10-01

Foam appears regularly in anaerobic digesters producing operational and safety problems. In this research, based on the operational observation at semi-industrial pilot scale where sludge pretreatment mitigated foaming in anaerobic digesters, this study aimed at evaluating any potential relationship between foaming tools applied to activated sludge at lab-scale (foam potential, foam stability and Microthrix parvicella abundance) and the experimental behavior observed in pilot scale and full-scale anaerobic digesters. The potential of thermal hydrolysis and ultrasounds for reducing foaming capacity was also evaluated. Filamentous bacteria abundance was directly linked to foaming capacity in anaerobic processes. A maximum reduction of M.parvicella abundance (from 5 to 2) was reached using thermal hydrolysis with steam explosion at 170°C and ultrasounds at 66.7kWh/m(3), showing both good anti-foaming properties. On the other hand, foam potential and stability determinations showed a lack of consistency with the bacteria abundance results and experimental evidences. Copyright © 2014 Elsevier Ltd. All rights reserved.

Nonthermal processing of orange juice using a pilot-plant scale supercritical carbon dioxide system with a gas-liquid metal contactor

USDA-ARS?s Scientific Manuscript database

To evaluate the effect of pilot-plant scale, non-thermal supercritical carbon dioxide (SCCO2) processing on the safety and the quality of orange juice (OJ), SCCO2 processed juice was compared with untreated fresh juice and equivalently thermal processed juice in terms of lethality. SCCO2 processing ...

Final report from VFL Technologies for the pilot-scale thermal treatment of Lower East Fork Poplar Creek floodplain soils. LEFPC appendices. Volume 5. Appendix V-D

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1994-09-01

This final report from VFL Technologies for the pilot-scale thermal treatment of lower East Fork Poplar Creek floodplain soils dated September 1994 contains LEFPC Appendices, Volume 5, Appendix V - D. This appendix includes the final verification run data package (PAH, TCLP herbicides, TCLP pesticides).

DEMONSTRATION OF PILOT-SCALE PREVAPORATION SYSTEMS FOR VOLATILE ORGANIC COMPOUND REMOVAL FROM A SURFACTANT ENHANCED AQUIFER REMEDIATION FLUID. I. SPIRAL WOUND MEMBRANE MODULES

EPA Science Inventory

During the summer of 1996, a pilot-scale demonstration of a surfactant enhanced aquifer remediation (SEAR) process for removal of dense non-aqueous phase liquids (DNAPLs) from soils was conducted at Hill Air Force Base in Layton, Utah. Five thousand gallons of the extracted DNAP...

Commissioning Source and Personality Differences in U.S. Air Force Pilot Training

DTIC Science & Technology

2012-09-24

Narcissistic Personality Disorder and Histrionic Personality Disorder. The two tests generally converged, showing student pilots as socially outgoing...Histrionic, Narcissistic , and Antisocial scales of the MCMI. Cluster two students scored high on the Achievement, Affiliation, Endurance, and Social...Desirability scales but low on Dependence. In addition, they had moderate Narcissistic and Histrionic scores and high Compulsive Personality Disorder

Superfund Technology Evaluation Report: SITE Program Demonstration Test Shirco Pilot-Scale Infrared Incineration System at the Rose Township Demode Road Superfund Site Volume I

EPA Science Inventory

The Shirco Pilot-Scale Infrared Incineration System was evaluated during a series of seventeen test runs under varied operating conditions at the Demode Road Superfund Site located in Rose Township, Michigan. The tests sought to demonstrate the effectiveness of the unit and the t...

Pilot-scale testing of renewable biocatalyst for swine manure treatment and mitigation of odorous VOCs, ammonia and hydrogen sulfide emissions

USDA-ARS?s Scientific Manuscript database

Comprehensive control of odors, hydrogen sulfide (H2S), ammonia (NH3), and greenhouse gas (GHG) emissions associated with swine production is a critical need. A pilot-scale experiment was conducted to evaluate the topical application of soybean peroxidase (SBP) and calcium peroxide (CaO2) as a manu...

Developmental neuropsychological assessment of 4- to 5-year-old children born following Preimplantation Genetic Diagnosis (PGD): A pilot study.

PubMed

Sacks, Gilat Chaya; Altarescu, Gheona; Guedalia, Judith; Varshaver, Irit; Gilboa, Tal; Levy-Lahad, Ephrat; Eldar-Geva, Talia

2016-01-01

The purpose of this pilot study was to evaluate developmental neuropsychological profiles of 4- to 5-year-old children born after Preimplantation Genetic Diagnosis (PGD). Twenty-seven participants received a neurological examination and a battery of neuropsychological assessments including Wechsler Preschool & Primary Scale of Intelligence - Third Edition (WPPSI-III; cognitive development), Preschool Language Scale, Fourth Edition (PLS-4; language development), Wide Range Assessment of Visual Motor Abilities (visual motor abilities), Childhood Autism Rating Scales II (a screening test for autistic spectrum disorders), and the Miles ABC Test (ocular dominance). Parental questionnaires included the Behavior Rating Inventory of Executive Function Preschool Version (BRIEF-P; executive function), Child Behavior Checklist (CBCL) and the Carey Temperament Scales Behavioral Style Questionnaire (socioemotional development and temperament), and the Vineland Adaptive Behavior Scales, Interview Edition, Second Edition (general adaptive behavior). Subjects' tests results were compared to each test's norms. Children born after PGD demonstrated scores within the normal or above-normal ranges for all developmental outcomes (mean ± SD): WPPSI-III-VIQ 107.4 ± 14.4 (p = .013), PLS-4-Total 113.2 ± 12.4, p < .001), CBCL-Total 41.1 ± 8.6 (p < .001), BRIEF-P-Global Executive Composite 44.8 ± 9.5 (p = .009). Twelve (44%) of the PGD children had a significant difference between their VIQ and PIQ scores (compared to 27% in the general population). One subject was found to show possible signs of autistic spectrum disorder, although a family history of autism was noted. In conclusion, in this pilot study, children assessed at age 4-5 years and conceived after PGD displayed developmental neuropsychological outcomes within normal limits as compared to their chronologic peers. A larger study is needed to evaluate and follow the neuropsychological development of children born after PGD.

Accumulation and Fate of Microorganisms and Microspheres in Biofilms Formed in a Pilot-Scale Water Distribution System

PubMed Central

Långmark, Jonas; Storey, Michael V.; Ashbolt, Nicholas J.; Stenström, Thor-Axel

2005-01-01

The accumulation and fate of model microbial “pathogens” within a drinking-water distribution system was investigated in naturally grown biofilms formed in a novel pilot-scale water distribution system provided with chlorinated and UV-treated water. Biofilms were exposed to 1-μm hydrophilic and hydrophobic microspheres, Salmonella bacteriophages 28B, and Legionella pneumophila bacteria, and their fate was monitored over a 38-day period. The accumulation of model pathogens was generally independent of the biofilm cell density and was shown to be dependent on particle surface properties, where hydrophilic spheres accumulated to a larger extent than hydrophobic ones. A higher accumulation of culturable legionellae was measured in the chlorinated system compared to the UV-treated system with increasing residence time. The fate of spheres and fluorescence in situ hybridization-positive legionellae was similar and independent of the primary disinfectant applied and water residence time. The more rapid loss of culturable legionellae compared to the fluorescence in situ hybridization-positive legionellae was attributed to a loss in culturability rather than physical desorption. Loss of bacteriophage 28B plaque-forming ability together with erosion may have affected their fate within biofilms in the pilot-scale distribution system. The current study has demonstrated that desorption was one of the primary mechanisms affecting the loss of microspheres, legionellae, and bacteriophage from biofilms within a pilot-scale distribution system as well as disinfection and biological grazing. In general, two primary disinfection regimens (chlorination and UV treatment) were not shown to have a measurable impact on the accumulation and fate of model microbial pathogens within a water distribution system. PMID:15691920

Accumulation and fate of microorganisms and microspheres in biofilms formed in a pilot-scale water distribution system.

PubMed

Långmark, Jonas; Storey, Michael V; Ashbolt, Nicholas J; Stenström, Thor-Axel

2005-02-01

The accumulation and fate of model microbial "pathogens" within a drinking-water distribution system was investigated in naturally grown biofilms formed in a novel pilot-scale water distribution system provided with chlorinated and UV-treated water. Biofilms were exposed to 1-mum hydrophilic and hydrophobic microspheres, Salmonella bacteriophages 28B, and Legionella pneumophila bacteria, and their fate was monitored over a 38-day period. The accumulation of model pathogens was generally independent of the biofilm cell density and was shown to be dependent on particle surface properties, where hydrophilic spheres accumulated to a larger extent than hydrophobic ones. A higher accumulation of culturable legionellae was measured in the chlorinated system compared to the UV-treated system with increasing residence time. The fate of spheres and fluorescence in situ hybridization-positive legionellae was similar and independent of the primary disinfectant applied and water residence time. The more rapid loss of culturable legionellae compared to the fluorescence in situ hybridization-positive legionellae was attributed to a loss in culturability rather than physical desorption. Loss of bacteriophage 28B plaque-forming ability together with erosion may have affected their fate within biofilms in the pilot-scale distribution system. The current study has demonstrated that desorption was one of the primary mechanisms affecting the loss of microspheres, legionellae, and bacteriophage from biofilms within a pilot-scale distribution system as well as disinfection and biological grazing. In general, two primary disinfection regimens (chlorination and UV treatment) were not shown to have a measurable impact on the accumulation and fate of model microbial pathogens within a water distribution system.

Bioaugmentation of a wastewater bioreactor system with the nitrous oxide-reducing denitrifier Pseudomonas stutzeri strain TR2.

PubMed

Ikeda-Ohtsubo, Wakako; Miyahara, Morio; Kim, Sang-Wan; Yamada, Takeshi; Matsuoka, Masaki; Watanabe, Akira; Fushinobu, Shinya; Wakagi, Takayoshi; Shoun, Hirofumi; Miyauchi, Keisuke; Endo, Ginro

2013-01-01

In bioaugmentation technology, survival of inoculant in the treatment system is prerequisite but remains to be a crucial hurdle. In this study, we bioaugmented the denitrification tank of a piggery wastewater treatment system with the denitrifying bacterium Pseudomonas stutzeri strain TR2 in two pilot-scale experiments, with the aim of reducing nitrous oxide (N(2)O), a gas of environmental concern. In the laboratory, strain TR2 grew well and survived with high concentrations of nitrite (5-10 mM) at a wide range of temperatures (28-40°C). In the first augmentation of the pilot-scale experiment, strain TR2 inoculated into the denitrification tank with conditions (30°C, ~0.1 mM nitrite) survived only 2-5 days. In contrast, in the second augmentation with conditions determined to be favorable for the growth of the bacterium in the laboratory (40-45°C, 2-5 mM nitrite), strain TR2 survived longer than 32 days. During the time when the presence of strain TR2 was confirmed by quantitative real-time PCR, N(2)O emission was maintained at a low level even under nitrite-accumulating conditions in the denitrification and nitrification tanks, which provided indirect evidence that strain TR2 can reduce N(2)O in the pilot-scale system. Our results documented the effective application of growth conditions favorable for strain TR2 determined in the laboratory to maintain growth and performance of this strain in the pilot-scale reactor system and the decrease of N(2)O emission as the consequence. Copyright © 2012 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

Optimization of instant powdered chicken feet broth’s drying temperature and time on pilot plant scale production

NASA Astrophysics Data System (ADS)

Hidayati, N.; Widyaningsih, T. D.

2018-03-01

Chicken feet by-product of chicken industries amounted to approximately 65,894 tons/year commonly used as broths. These by-products are potentially produced into an instant form as an anti-inflammatory functional food on industrial scale. Therefore, it is necessary to optimize the critical parameters of the drying process. The aim of this study was to determine the optimum temperature and time of instant powdered chicken feet broth’s drying on pilot plant scale, to find out product’s comparison of the laboratory and pilot plant scale, and to assess financial feasibility of the business plan. The optimization of pilot plant scale’s research prepared and designed with Response Surface Methodology-Central Composite Design. The optimized factors were powdered broth’s drying temperature (55°C, 60°C, 65°C) and time (10 minutes, 11 minutes, 12 minutes) with the response observed were water and chondroitin sulphate content. The optimum condition obtained was drying process with temperature of 60.85°C for 10,05 minutes resulting in 1.90 ± 0.02% moisture content, 32.48 ± 0.28% protein content, 12.05 ± 0.80% fat content, 28.92 ± 0.09 % ash content, 24.64 ± 0.52% carbohydrate content, 1.26 ± 0.05% glucosamine content, 0.99 ± 0.23% chondroitin sulphate content, 50.87 ± 1.00% solubility, 8.59 ± 0.19% water vapour absorption, 0.37% levels of free fatty acid, 13.66 ± 4.49% peroxide number, lightness of 60.33 ± 1.24, yellowness of 3.83 ± 0.26 and redness of 21.77 ± 0.42. Financial analysis concluded that this business project was feasible to run.

Complexity and Pilot Workload Metrics for the Evaluation of Adaptive Flight Controls on a Full Scale Piloted Aircraft

NASA Technical Reports Server (NTRS)

Hanson, Curt; Schaefer, Jacob; Burken, John J.; Larson, David; Johnson, Marcus

2014-01-01

Flight research has shown the effectiveness of adaptive flight controls for improving aircraft safety and performance in the presence of uncertainties. The National Aeronautics and Space Administration's (NASA)'s Integrated Resilient Aircraft Control (IRAC) project designed and conducted a series of flight experiments to study the impact of variations in adaptive controller design complexity on performance and handling qualities. A novel complexity metric was devised to compare the degrees of simplicity achieved in three variations of a model reference adaptive controller (MRAC) for NASA's F-18 (McDonnell Douglas, now The Boeing Company, Chicago, Illinois) Full-Scale Advanced Systems Testbed (Gen-2A) aircraft. The complexity measures of these controllers are also compared to that of an earlier MRAC design for NASA's Intelligent Flight Control System (IFCS) project and flown on a highly modified F-15 aircraft (McDonnell Douglas, now The Boeing Company, Chicago, Illinois). Pilot comments during the IRAC research flights pointed to the importance of workload on handling qualities ratings for failure and damage scenarios. Modifications to existing pilot aggressiveness and duty cycle metrics are presented and applied to the IRAC controllers. Finally, while adaptive controllers may alleviate the effects of failures or damage on an aircraft's handling qualities, they also have the potential to introduce annoying changes to the flight dynamics or to the operation of aircraft systems. A nuisance rating scale is presented for the categorization of nuisance side-effects of adaptive controllers.

PCB in the environment: bio-based processes for soil decontamination and management of waste from the industrial production of Pleurotus ostreatus.

PubMed

Siracusa, Giovanna; Becarelli, Simone; Lorenzi, Roberto; Gentini, Alessandro; Di Gregorio, Simona

2017-10-25

Polychlorinated biphenyls (PCBs) are hazardous soil contaminants for which a bio-based technology for their recovery is essential. The objective of this study was to validate the exploitation of spent mushroom substrate (SMS), a low or null cost organic waste derived from the industrial production of P. ostreatus, as bulking agent in a dynamic biopile pilot plant. The SMS shows potential oxidative capacity towards recalcitrant compounds. The aim was consistent with the design of a process of oxidation of highly chlorinated PCBs, which is independent from their reductive dehalogenation. Feasibility was verified at a mesocosm scale and validated at pilot scale in a dynamic biopile pilot plant treating ten tons of a historically contaminated soil (9.28±0.08mg PCB/kg soil dry weight). Mixing of the SMS with the soil was required for the depletion of the contaminants. At the pilot scale, after eight months of incubation, 94.1% depletion was recorded. A positive correlation between Actinobacteria and Firmicutes active metabolism, soil laccase activity and PCB removal was observed. The SMS was found to be exploitable as a versatile low cost organic substrate capable of activating processes for the oxidation of highly chlorinated PCBs. Moreover, its exploitation as bulking agent in biopiles is a valuable management strategy for the re-utilisation of an organic waste deriving from the industrial cultivation of edible mushrooms. Copyright © 2017 Elsevier B.V. All rights reserved.

A pilot-scale study on PVA gel beads based integrated fixed film activated sludge (IFAS) plant for municipal wastewater treatment.

PubMed

Kumar Singh, Nitin; Singh, Jasdeep; Bhatia, Aakansha; Kazmi, A A

2016-01-01

In the present study, a pilot-scale reactor incorporating polyvinyl alcohol gel beads as biomass carrier and operating in biological activated sludge mode (a combination of moving bed biofilm reactor (MBBR) and activated sludge) was investigated for the treatment of actual municipal wastewater. The results, during a monitoring period of 4 months, showed effective removal of chemical oxygen demand (COD), biological oxygen demand (BOD) and NH3-N at optimum conditions with 91%, ∼92% and ∼90% removal efficiencies, respectively. Sludge volume index (SVI) values of activated sludge varied in the range of 25-72 mL/g, indicating appreciable settling characteristics. Furthermore, soluble COD and BOD in the effluent of the pilot plant were reduced to levels well below discharge limits of the Punjab Pollution Control Board, India. A culture dependent method was used to enrich and isolate abundant heterotrophic bacteria in activated sludge. In addition to this, 16S rRNA genes analysis was performed to identify diverse dominant bacterial species in suspended and attached biomass. Results revealed that Escherichia coli, Pseudomonas sp. and Nitrosomonas communis played a significant role in biomass carrier, while Acinetobactor sp. were dominant in activated sludge of the pilot plant. Identification of ciliated protozoa populations rendered six species of ciliates in the plant, among which Vorticella was the most dominant.

Establishing an Operational Data System for Surface Currents Derived from Satellite Altimeters and Scatterometers; Pilot Study for the Tropical Pacific

NASA Astrophysics Data System (ADS)

Lagerloef, G. S.; Cheney, R.; Mitchum, G. T.

2001-12-01

We are initiating a pilot processing system and data center to provide operational ocean surface velocity fields from satellite altimeter and vector wind data. The team includes the above authors plus M. Bourassa (FSU), V.Kousky (NOAA/NCEP), J.Polovina (NOAA/NMFS/Hawaii CoastWatch), R.Legeckis (NOAA/NESDIS), G. Jacobs (NRL), F. Bonjean (ESR), E.Johnson (ESR) and J.Gunn (ESR). Methods to derive surface currents are the outcome of several years of NASA sponsored research and the pilot project will transition that capability to operational oceanographic applications. The regional focus will be the tropical Pacific. Data applications include large scale climate diagnostics and prediction, fisheries management and recruitment, monitoring debris drift, larvae drift, oil spills, fronts and eddies. Additional uses for search and rescue, naval and maritime operations will be investigated. The pilot study will produce velocity maps to be updated on a weekly basis initially, with a goal for eventual 2-day maximum delay from time of satellite measurement. Grid resolution will be 100 km for the basin scale, and finer resolution in the vicinity of the Pacific Islands. Various illustrations of the velocity maps and their applications will be presented. The project's goal is to leave in place an automated system running at NOAA/NESDIS, with an established user clientele and open Internet data access.

Alkaline fermentation of waste activated sludge stimulated by saponin: volatile fatty acid production, mechanisms and pilot-scale application.

PubMed

Huang, Xiangfeng; Mu, Tianshuai; Shen, Changming; Lu, Lijun; Liu, Jia

2016-12-01

Volatile fatty acid (VFA) production stimulated by saponin (SP), an environmentally friendly bio-surfactant, was investigated during sludge alkaline fermentation in laboratory studies and pilot applications. The combined use of SP and pH 9 condition significantly enhanced VFA production to approximately 425 mg COD/g VSS, which was 4.7-fold of raw sludge and 1.5-fold of sole pH 10 adjustment (the optimum pH for alkaline fermentation). Further results indicated that SP & pH 9 condition provided sufficient substrates for acidification and decreased the consumption of VFAs through methanogenesis. Moreover, SP accompanied by moderate alkaline condition (i.e. pH 9) showed weaker inhibitory effects on key enzyme activities and metabolic potential of acidification microorganisms than sole pH 10 adjustment. On this basis, a pilot-scale system involving anaerobic fermentation and anaerobic-anoxic-aerobic step-feed bioreaction tanks was established to study the potential of VFAs as supplementary carbon sources for wastewater treatment. The influent of the pilot system was sanitary wastewater characterized by low C/N ratios from a scenic rural area. After flocculation and nutrient precipitation, the fermentation supernatant was mixed with the influent at a volume ratio of 1:30. With this approach, nitrogen and phosphorus concentrations in effluent fulfilled the first-A wastewater discharge standard in China.

Identifying the support needs of fathers affected by post-partum depression: a pilot study.

PubMed

Letourneau, N; Duffett-Leger, L; Dennis, C-L; Stewart, M; Tryphonopoulos, P D

2011-02-01

The purpose of this pilot study was to describe the experiences, support needs, resources, and barriers to support for fathers whose partners had post-partum depression (PPD) in preparation for a larger study. Qualitative methods and community-based research approaches were used in this exploratory/descriptive multi-site study, conducted in New Brunswick and Alberta. Telephone interviews were conducted with a total of 11 fathers in New Brunswick (n= 7) and Alberta (n= 4). Fathers experienced a number of depressive symptoms including: anxiety, lack of time and energy, irritability, feeling sad or down, changes in appetite, and thoughts of harm to self or baby. The most common barriers for fathers were lack of information regarding PPD resources and difficulty seeking support. This pilot study establishes the feasibility of the larger-scale exploration of fathers' experiences in supporting their spouses affected by PPD. © 2010 Blackwell Publishing.

A Pilot SMART for Developing an Adaptive Treatment Strategy for Adolescent Depression.

PubMed

Gunlicks-Stoessel, Meredith; Mufson, Laura; Westervelt, Ana; Almirall, Daniel; Murphy, Susan

2016-01-01

This pilot study was conducted to assess the feasibility and acceptability of 4 adaptive treatment strategies (ATSs) for adolescent depression to plan for a subsequent full-scale clinical trial. The ATSs aim to address 2 questions that arise when personalizing treatment: (a) For adolescents treated with Interpersonal Psychotherapy for depressed adolescents (IPT-A; Mufson et al., 2004 ), at what time point should therapists make the determination that the adolescent is not likely to respond if the initial treatment plan is continued (week 4 or week 8)? (b) For adolescents who are judged to need their treatment augmented, should the therapist increase the number of IPT-A sessions or add pharmacotherapy (fluoxetine)? A 16-week pilot sequential multiple assignment randomized trial (SMART) was conducted with 32 adolescents (M age = 14.9) who had a diagnosis of major depressive disorder, dysthymic disorder, or depressive disorder not otherwise specified. Adolescents were primarily female (75%) and Caucasian (84.4%). Data regarding the feasibility and acceptability of the study and treatment procedures and treatment response rates were collected. Week 4 was the more feasible and acceptable decision point for assessing need for a change to treatment. Adolescents, parents, and therapists reported a range of attitudes about medication and more intensive therapy as treatment options. Results from the pilot study have yielded additional research questions for the full-scale SMART and will improve our ability to successfully conduct the trial.

Enhancing Baccalaureate Nursing Students' Perception of Competence and Confidence During an Alternative Dedicated Education Unit Experience: A Pilot Study.

PubMed

Schecter, Rose; Gallagher, Joan; Ryan, Marybeth

This quasiexperimental pilot study explored the effect three consecutive adult health Dedicated Education Unit (DEU) clinical placements would have on baccalaureate nursing students' self-perception of growth in competence and confidence. A Likert-type Competence/Confidence Self-Assessment Scale was constructed as a pretest/posttest measure; competence and confidence posttest means increased in each course. The study provides nursing professional development practitioners with information about the alternative DEU concept, its effect on student outcomes, and benefits nursing staff can gain by participating in a DEU experience.

Urban forest health monitoring: large-scale assessments in the United States

Treesearch

Anne Buckelew Cumming; Daniel B. Twardus; David J. Nowak

2008-01-01

The U.S. Department of Agriculture, Forest Service (USFS), together with state partners, developed methods to monitor urban forest structure, function, and health at a large statewide scale. Pilot studies have been established in five states using protocols based on USFS Forest Inventory and Analysis and Forest Health Monitoring program data collection standards....

Systems approach to monitoring and evaluation guides scale up of the Standard Days Method of family planning in Rwanda.

PubMed

Igras, Susan; Sinai, Irit; Mukabatsinda, Marie; Ngabo, Fidele; Jennings, Victoria; Lundgren, Rebecka

2014-05-01

There is no guarantee that a successful pilot program introducing a reproductive health innovation can also be expanded successfully to the national or regional level, because the scaling-up process is complex and multilayered. This article describes how a successful pilot program to integrate the Standard Days Method (SDM) of family planning into existing Ministry of Health services was scaled up nationally in Rwanda. Much of the success of the scale-up effort was due to systematic use of monitoring and evaluation (M&E) data from several sources to make midcourse corrections. Four lessons learned illustrate this crucially important approach. First, ongoing M&E data showed that provider training protocols and client materials that worked in the pilot phase did not work at scale; therefore, we simplified these materials to support integration into the national program. Second, triangulation of ongoing monitoring data with national health facility and population-based surveys revealed serious problems in supply chain mechanisms that affected SDM (and the accompanying CycleBeads client tool) availability and use; new procedures for ordering supplies and monitoring stockouts were instituted at the facility level. Third, supervision reports and special studies revealed that providers were imposing unnecessary medical barriers to SDM use; refresher training and revised supervision protocols improved provider practices. Finally, informal environmental scans, stakeholder interviews, and key events timelines identified shifting political and health policy environments that influenced scale-up outcomes; ongoing advocacy efforts are addressing these issues. The SDM scale-up experience in Rwanda confirms the importance of monitoring and evaluating programmatic efforts continuously, using a variety of data sources, to improve program outcomes.

Systems approach to monitoring and evaluation guides scale up of the Standard Days Method of family planning in Rwanda

PubMed Central

Igras, Susan; Sinai, Irit; Mukabatsinda, Marie; Ngabo, Fidele; Jennings, Victoria; Lundgren, Rebecka

2014-01-01

There is no guarantee that a successful pilot program introducing a reproductive health innovation can also be expanded successfully to the national or regional level, because the scaling-up process is complex and multilayered. This article describes how a successful pilot program to integrate the Standard Days Method (SDM) of family planning into existing Ministry of Health services was scaled up nationally in Rwanda. Much of the success of the scale-up effort was due to systematic use of monitoring and evaluation (M&E) data from several sources to make midcourse corrections. Four lessons learned illustrate this crucially important approach. First, ongoing M&E data showed that provider training protocols and client materials that worked in the pilot phase did not work at scale; therefore, we simplified these materials to support integration into the national program. Second, triangulation of ongoing monitoring data with national health facility and population-based surveys revealed serious problems in supply chain mechanisms that affected SDM (and the accompanying CycleBeads client tool) availability and use; new procedures for ordering supplies and monitoring stockouts were instituted at the facility level. Third, supervision reports and special studies revealed that providers were imposing unnecessary medical barriers to SDM use; refresher training and revised supervision protocols improved provider practices. Finally, informal environmental scans, stakeholder interviews, and key events timelines identified shifting political and health policy environments that influenced scale-up outcomes; ongoing advocacy efforts are addressing these issues. The SDM scale-up experience in Rwanda confirms the importance of monitoring and evaluating programmatic efforts continuously, using a variety of data sources, to improve program outcomes. PMID:25276581

Design and fabrication of a fixed-bed batch type pyrolysis reactor for pilot scale pyrolytic oil production in Bangladesh

NASA Astrophysics Data System (ADS)

Aziz, Mohammad Abdul; Al-khulaidi, Rami Ali; Rashid, MM; Islam, M. R.; Rashid, MAN

2017-03-01

In this research, a development and performance test of a fixed-bed batch type pyrolysis reactor for pilot scale pyrolysis oil production was successfully completed. The characteristics of the pyrolysis oil were compared to other experimental results. A solid horizontal condenser, a burner for furnace heating and a reactor shield were designed. Due to the pilot scale pyrolytic oil production encountered numerous problems during the plant’s operation. This fixed-bed batch type pyrolysis reactor method will demonstrate the energy saving concept of solid waste tire by creating energy stability. From this experiment, product yields (wt. %) for liquid or pyrolytic oil were 49%, char 38.3 % and pyrolytic gas 12.7% with an operation running time of 185 minutes.

Validation of the Expanded Versions of the Adult ADHD Self-Report Scale v1.1 Symptom Checklist and the Adult ADHD Investigator Symptom Rating Scale.

PubMed

Silverstein, Michael J; Faraone, Stephen V; Alperin, Samuel; Leon, Terry L; Biederman, Joseph; Spencer, Thomas J; Adler, Lenard A

2018-02-01

The aim of this study is to validate the Adult ADHD Self-Report Scale (ASRS) and Adult ADHD Investigator Symptom Rating Scale (AISRS) expanded versions, including executive function deficits (EFDs) and emotional dyscontrol (EC) items, and to present ASRS and AISRS pilot normative data. Two patient samples (referred and primary care physician [PCP] controls) were pooled together for these analyses. Final analysis included 297 respondents, 171 with adult ADHD. Cronbach's alphas were high for all sections of the scales. Examining histograms of ASRS 31-item and AISRS 18-item total scores for ADHD controls, 95% cutoff scores were 70 and 23, respectively; histograms for pilot normative sample suggest cutoffs of 82 and 26, respectively. (a) ASRS- and AISRS-expanded versions have high validity in assessment of core 18 adult ADHD Diagnostic and Statistical Manual of Mental Disorders ( DSM) symptoms and EFD and EC symptoms. (b) ASRS (31-item) scores 70 to 82 and AISRS (18-item) scores from 23 to 26 suggest a high likelihood of adult ADHD.

The Development of a Cell-Assembly for the Treatment of Irradiated Fuels on a Semi-Industrial Scale; ETUDE CONCERNANT LA REALISATION D'UN ENSEMBLE DE CELLULES DESTINEES A DES TRAITEMENTS DE COMBUSTIBLES IRRADIES A L'ECHELLE SEMI-INDUSTRIELLE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Faugeras, P.; Couture, J.; Lefort, G.

1961-01-01

The main studies and experiments involved in the development of a cell- assembly for the treatment of irradiated fuels on a semi-industrial scale are described. It must be possible to modify or transform each of these cells without interrupting the rest of the pilot. A full-scale prototype cell ( 3 x 4 x 6 m) was built with an alpha k-protection independent of the gamma - protection. It features all the main characteristics: tightness to gamma losses, dense glass lighting, and ventilation. This cell has made possible trials on transfer, remote-controls and teledismantling, as well as the development of newmore » methods of rapidly connecting hydraulic circuits. The final form is given of the cells selected for the pilot. (auth)« less

Experimental Study on Hot Metal Desulfurization Using Sintered Red Mud-Based Flux

NASA Astrophysics Data System (ADS)

Li, Fengshan; Zhang, Yanling; Guo, Zhancheng

2017-09-01

This research presents the results of laboratory and pilot-scale tests conducted on the use of sintered red mud (RM)-based flux in the hot metal desulfurization (HMD) process. Al2O3/Na2O in RM can decrease the melting point of lime-based slag and can work as a flux in the HMD process. Good slag fluidity was observed throughout the process, and high desulfurization rates ( 80%) with a low final S content (<0.02%) were experimentally obtained when the RM:CaO ratio was between 1.2:1 and 2.4:1. The pilot-scale test results indicated that a desulfurization rate as high as 91% and a S content <0.0099% could be acquired when RM:lime = 1:1, verifying the feasibility of using sintered RM-based flux in HMD. The data obtained provide important information for promoting the large-scale application of sintered RM in steelmaking.

Development of a versatile high-temperature short-time (HTST) pasteurization device for small-scale processing of cell culture medium formulations.

PubMed

Floris, Patrick; Curtin, Sean; Kaisermayer, Christian; Lindeberg, Anna; Bones, Jonathan

2018-07-01

The compatibility of CHO cell culture medium formulations with all stages of the bioprocess must be evaluated through small-scale studies prior to scale-up for commercial manufacturing operations. Here, we describe the development of a bespoke small-scale device for assessing the compatibility of culture media with a widely implemented upstream viral clearance strategy, high-temperature short-time (HTST) treatment. The thermal stability of undefined medium formulations supplemented with soy hydrolysates was evaluated upon variations in critical HTST processing parameters, namely, holding times and temperatures. Prolonged holding times of 43 s at temperatures of 110 °C did not adversely impact medium quality while significant degradation was observed upon treatment at elevated temperatures (200 °C) for shorter time periods (11 s). The performance of the device was benchmarked against a commercially available mini-pilot HTST system upon treatment of identical formulations on both platforms. Processed medium samples were analyzed by untargeted LC-MS/MS for compositional profiling followed by chemometric evaluation, which confirmed the observed degradation effects caused by elevated holding temperatures but revealed comparable performance of our developed device with the commercial mini-pilot setup. The developed device can assist medium optimization activities by reducing volume requirements relative to commercially available mini-pilot instrumentation and by facilitating fast throughput evaluation of heat-induced effects on multiple medium lots.

Development of a Social Skills Assessment Screening Scale for Psychiatric Rehabilitation Settings: A Pilot Study.

PubMed

Bhola, Poornima; Basavarajappa, Chethan; Guruprasad, Deepti; Hegde, Gayatri; Khanam, Fatema; Thirthalli, Jagadisha; Chaturvedi, Santosh K

2016-01-01

Deficits in social skills may present in a range of psychiatric disorders, particularly in the more serious and persistent conditions, and have an influence on functioning across various domains. This pilot study aimed at developing a brief measure, for structured evaluation and screening for social skills deficits, which can be easily integrated into routine clinical practice. The sample consisted of 380 inpatients and their accompanying caregivers, referred to Psychiatric Rehabilitation Services at a tertiary care government psychiatric hospital. The evaluation included an Inpatient intake Proforma and the 20-item Social Skills Assessment Screening Scale (SSASS). Disability was assessed using the Indian Disability Evaluation and Assessment Scale (IDEAS) for a subset of 94 inpatients. The analysis included means and standard deviations, frequency and percentages, Cronbach's alpha to assess internal consistency, t -tests to assess differences in social skills deficits between select subgroups, and correlation between SSASS and IDEAS scores. The results indicated the profile of social skills deficits assessed among the inpatients with varied psychiatric diagnoses. The "psychosis" group exhibited significantly higher deficits than the "mood disorder" group. Results indicated high internal consistency of the SSASS and adequate criterion validity demonstrated by correlations with select IDEAS domains. Modifications were made to the SSASS following the pilot study. The SSASS has potential value as a measure for screening and individualised intervention plans for social skills training in mental health and rehabilitation settings. The implications for future work on the psychometric properties and clinical applications are discussed.

Anthropometry of Brazilian Air Force pilots.

PubMed

da Silva, Gilvan V; Halpern, Manny; Gordon, Claire C

2017-10-01

Anthropometric data are essential for the design of military equipment including sizing of aircraft cockpits and personal gear. Currently, there are no anthropometric databases specific to Brazilian military personnel. The aim of this study was to create a Brazilian anthropometric database of Air Force pilots. The methods, protocols, descriptions, definitions, landmarks, tools and measurements procedures followed the instructions outlined in Measurer's Handbook: US Army and Marine Corps Anthropometric Surveys, 2010-2011 - NATICK/TR-11/017. The participants were measured countrywide, in all five Brazilian Geographical Regions. Thirty-nine anthropometric measurements related to cockpit design were selected. The results of 2133 males and 206 females aged 16-52 years constitute a set of basic data for cockpit design, space arrangement issues and adjustments, protective gear and equipment design, as well as for digital human modelling. Another important implication is that this study can be considered a starting point for reducing gender bias in women's career as pilots. Practitioner Summary: This paper describes the first large-scale anthropometric survey of the Brazilian Air Force pilots and the development of the related database. This study provides critical data for improving aircraft cockpit design for ergonomics and comprehensive pilot accommodation, protective gear and uniform design, as well as digital human modelling.

Subsonic stability and control derivatives for an unpowered, remotely piloted 3/8-scale F-15 airplane model obtained from flight test

NASA Technical Reports Server (NTRS)

Iliff, K. W.; Maine, R. E.; Shafer, M. F.

1976-01-01

In response to the interest in airplane configuration characteristics at high angles of attack, an unpowered remotely piloted 3/8-scale F-15 airplane model was flight tested. The subsonic stability and control characteristics of this airplane model over an angle of attack range of -20 to 53 deg are documented. The remotely piloted technique for obtaining flight test data was found to provide adequate stability and control derivatives. The remotely piloted technique provided an opportunity to test the aircraft mathematical model in an angle of attack regime not previously examined in flight test. The variation of most of the derivative estimates with angle of attack was found to be consistent, particularly when the data were supplemented by uncertainty levels.

EMAP WESTERN UNITED STATES LANDSCAPE CHARACTERIZATION NORTHERN CALIFORNIA DATA BROWSER

EPA Science Inventory

The United States Environmental Protection Agency's Environmental Monitoring and Assessment Program (EMAP) is conducting a pilot study in the western United States. This study will advance the science of ecological monitoring and demonstrate techniques for regional-scale asse...

Fate of NDMA precursors through an MBR-NF pilot plant for urban wastewater reclamation and the effect of changing aeration conditions.

PubMed

Mamo, Julian; Insa, Sara; Monclús, Hèctor; Rodríguez-Roda, Ignasi; Comas, Joaquim; Barceló, Damià; Farré, Maria José

2016-10-01

The removal of N-nitrosodimethylamine (NDMA) formation potential through a membrane bioreactor (MBR) coupled to a nanofiltration (NF) pilot plant that treats urban wastewater is investigated. The results are compared to the fate of the individual NDMA precursors detected: azithromycin, citalopram, erythromycin, clarithromycin, ranitidine, venlafaxine and its metabolite o-desmethylvenlafaxine. Specifically, the effect of dissolved oxygen in the aerobic chamber of the MBR pilot plant on the removal of NDMA formation potential (FP) and individual precursors is studied. During normal aerobic operation, implying a fully nitrifying system, the MBR was able to reduce NDMA precursors above 94%, however this removal percentage was reduced to values as low as 72% when changing the conditions to minimize nitrification. Removal decreased also for azithromycin (68-59%), citalopram (31-17%), venlafaxine (35-15%) and erythromycin (61-16%) on average during nitrifying versus non-nitrifying conditions. The removal of clarithromycin, o-desmethylvenlafaxine and ranitidine could not be correlated with the nitrification inhibition, as it varied greatly during the experiment time. The MBR pilot plant is coupled to a nanofiltration (NF) system and the results on the rejection of both, NDMA FP and individual precursors, through this system was above 90%. Finally, results obtained for the MBR pilot plant are compared to the percentage of removal by a conventional full scale biological wastewater treatment plant (WWTP) fed with the same influent. During aerobic operation, the removal of NDMA FP by the MBR pilot plant was similar to the full scale WWTP. Copyright © 2016 Elsevier Ltd. All rights reserved.

A pilot data collecting exercise on stress and nursing students.

PubMed

Por, Jitna

This article discusses the lessons learned from a small pilot study exploring the link between the working environment and occupational stress among groups of nursing students. A comparative descriptive design was adopted to examine, describe and compare the two variables (sources and frequency) in three groups of nursing students. The sample comprised 90 students from one large inner-city school of nursing in London. The Expanded Nursing Stress Scale questionnaires were used to collect the data. The main findings suggest that the adult, child and mental health branch students were similar with respect to overall frequency of occupational stress. Areas of commonality and variability in the sources of stress perceived by the three groups of students were identified. A pilot study is a crucial element of a good study design. Areas of concern, lessons learned and suggested refinements were identified.

What defines an effective anti-tobacco TV advertisement? A pilot study among Greek adolescents.

PubMed

Vardavas, Constantine I; Symvoulakis, Emmanouil K; Connolly, Gregory N; Patelarou, Evridiki; Lionis, Christos

2010-01-01

As the Framework Convention on Tobacco Control (FCTC) calls for public health awareness on tobacco use, mass media campaigns should be appropriately designed so as to maximize their effectiveness. In this methodological pilot study, 95 Greek adolescents (mean age 15 +/- 1.8 years), were shown seven different anti tobacco ads, and asked to rate the ad theme, message and emotional context on a 1-7 Likert scale. Health related ads were rated the highest, and as identified through the logistic regression analysis, adolescents who perceived an ad to be emotional or to have a clear message that was relevant to them, were more likely to rate the ad as more effective. The strong agreement between the above findings and the existing literature indicates the applicability of this pilot study's methodological approach.

Lessons learnt on recruitment and fieldwork from a pilot European human biomonitoring survey.

PubMed

Fiddicke, Ulrike; Becker, Kerstin; Schwedler, Gerda; Seiwert, Margarete; Joas, Reinhard; Joas, Anke; Biot, Pierre; Aerts, Dominique; Casteleyn, Ludwine; Dumez, Birgit; Castaño, Argelia; Esteban, Marta; Angerer, Jürgen; Koch, Holger M; Schoeters, Greet; Den Hond, Elly; Sepai, Ovnair; Exley, Karen; Knudsen, Lisbeth E; Horvat, Milena; Bloemen, Louis; Katsonouri, Andromachi; Hadjipanayis, Adamos; Cerna, Milena; Krsková, Andrea; Jensen, Janne Fangel; Nielsen, Jeanette K S; Rudnai, Peter; Közepésy, Szilvia; Gutleb, Arno C; Fischer, Marc E; Ligocka, Danuta; Kamińska, Joanna; Reis, M Fátima; Namorado, Sónia; Lupsa, Ioana-Rodica; Gurzau, Anca E; Halzlová, Katarína; Mazej, Darja; Tratnik, Janja Snoj; Rivas, Teresa C; Gómez, Silvia; Berglund, Marika; Larsson, Kristin; Lehmann, Andrea; Crettaz, Pierre; Dewolf, Marie-Christine; Burns, Damien; Kellegher, Anne; Kolossa-Gehring, Marike

2015-08-01

Within the European Environment and Health Action Plan an initiative to establish a coherent human biomonitoring approach in Europe was started. The project COPHES (COnsortium to Perform Human biomonitoring on a European Scale ) developed recommendations for a harmonized conduct of a human biomonitoring (HBM) survey which came into action as the pilot study DEMOCOPHES (DEMOnstration of a study to COordinate and Perform Human biomonitoring on a European Scale). Seventeen European countries conducted a survey with harmonized instruments for, inter alia, recruitment, fieldwork and sampling, in autumn/winter 2011/2012. Based on the countries' experiences of conducting the pilot study, following lessons learnt were compiled: the harmonized fieldwork instruments (basic questionnaire, urine and hair sampling) turned out to be very valuable for future HBM surveys on the European scale. A school approach was favoured by most of the countries to recruit school-aged children according to the established guidelines and country specific experiences. To avoid a low participation rate, intensive communication with the involved institutions and possible participants proved to be necessary. The communication material should also include information on exclusion criteria and offered incentives. Telephone contact to the participants the day before fieldwork during the survey can prevent the forgetting of appointments and first morning urine samples. To achieve comparable results on the European scale, training of interviewers in all issues of recruitment, fieldwork and sampling through information material and training sessions is crucial. A survey involving many European countries needs time for preparation and conduct. Materials for quality control prepared for all steps of recruitment, fieldwork and sampling proved to be important to warrant reliable results. Copyright © 2014 Elsevier Inc. All rights reserved.

Response to pentagastrin after acute phenylalanine and tyrosine depletion in healthy men: a pilot study.

PubMed Central

Coupland, N; Zedkova, L; Sanghera, G; Leyton, M; Le Mellédo, J M

2001-01-01

OBJECTIVE: To assess the effects of the acute depletion of the catecholamine precursors phenylalanine and tyrosine on mood and pentagastrin-induced anxiety. DESIGN: Randomized, double-blind controlled multiple crossover study. SETTING: University department of psychiatry. PARTICIPANTS: 6 healthy male volunteers. INTERVENTIONS: 3 treatments were compared: pretreatment with a nutritionally balanced amino acid mixture, followed 5 hours later by a bolus injection of normal saline placebo; pretreatment with a balanced amino acid mixture, followed by a bolus injection of pentagastrin (0.6 microgram/kg); and pretreatment with an amino acid mixture without the catecholamine precursors phenylalanine or tyrosine, followed by pentagastrin (0.6 microgram/kg). OUTCOME MEASURES: Scores on the panic symptom scale, a visual analogue scale for anxiety, the Borg scale of respiratory exertion and the Profile of Mood States Elation-Depression Scale. RESULTS: Pentagastrin produced the expected increases in anxiety symptoms, but there was no significant or discernible influence of acute phenylalanine and tyrosine depletion on anxiety or mood. CONCLUSIONS: These pilot data do not support further study using the same design in healthy men. Under these study conditions, phenylalanine and tyrosine depletion may have larger effects on dopamine than noradrenaline. Alternative protocols to assess the role of catecholamines in mood and anxiety are proposed. PMID:11394194

Biogasification of community-derived biomass and solid wastes in a pilot-scale SOLCON reactor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Srivastava, V.J.; Biljetina, R.; Isaacson, H.R.

1988-01-01

The Institute of Gas Technology has developed a novel, solids- concentrating (SOLCON) bioreactor to convert a variety of individual or mixed feedstocks (biomass and wastes) to methane at higher rates and efficiencies than those obtained from conventional high-rate anaerobic digesters. The biogasification studies are being conducted in a pilot-scale experimental test unit (ETU) located in the Walt Disney World Resort Complex, Orlando, Florida. This paper describes the ETU facility, the logistics of feedstock integration, the SOLCON reactor design and operating techniques, and the results obtained during 4 years of stable, uninterrupted operation with different feedstocks. The SOLCON reactor consistently outperformedmore » the conventional stirred-tank reactor by 20% to 50%.« less

Development of scales to assess patients' perception of physicians' cultural competence in health care interactions.

PubMed

Ahmed, Rukhsana; Bates, Benjamin R

2012-07-01

This study describes the development of scales to measure patients' perception of physicians' cultural competence in health care interactions and thus contributes to promoting awareness of physician-patient intercultural interaction processes. Surveys were administrated to a total of 682 participants. Exploratory factor analyses were employed to assess emergent scales and subscales to develop reliable instruments. The first two phases were devoted to formative research and pilot study. The third phase was devoted to scale development, which resulted in a five-factor solution to measure patient perception of physicians' cultural competence for patient satisfaction.

Activated carbon enhanced anaerobic digestion of food waste - Laboratory-scale and Pilot-scale operation.

PubMed

Zhang, Le; Zhang, Jingxin; Loh, Kai-Chee

2018-05-01

Effects of activated carbon (AC) supplementation on anaerobic digestion (AD) of food waste were elucidated in lab- and pilot-scales. Lab-scale AD was performed in 1 L and 8 L digesters, while pilot-scale AD was conducted in a 1000 L digester. Based on the optimal dose of 15 g AC per working volume derived from the 1 L digester, for the same AC dosage in the 8 L digester, an improved operation stability coupled with a higher methane yield was achieved even when digesters without AC supplementation failed after 59 days due to accumulation of substantial organic intermediates. At the same time, color removal from the liquid phase of the digestate was dramatically enhanced and the particle size of the digestate solids was increased by 53% through AC supplementation after running for 59 days. Pyrosequencing of 16S rRNA gene showed the abundance of predominant phyla Firmicutes, Elusimicrobia and Proteobacteria selectively enhanced by 1.7-fold, 2.9-fold and 2.1-fold, respectively. Pilot-scale digester without AC gave an average methane yield of 0.466 L⋅(gVS) -1 ⋅d -1 at a composition of 53-61% v/v methane. With AC augmentation, an increase of 41% in methane yield was achieved in the 1000 L digester under optimal organic loading rate (1.6 g VS FW ·L -1 ·d -1 ). Copyright © 2018 Elsevier Ltd. All rights reserved.

Manufacturing demonstration of microbially mediated zinc sulfide nanoparticles in pilot-plant scale reactors

DOE PAGES

Moon, Ji-Won; Phelps, Tommy J.; Fitzgerald Jr, Curtis L.; ...

2016-04-27

The thermophilic anaerobic metal-reducing bacterium Thermoanaerobacter sp. X513 efficiently produces zinc sulfide (ZnS) nanoparticles (NPs) in laboratory-scale ( ≤24-L) reactors. To determine whether this process can be up-scaled and adapted for pilot-plant production while maintaining NP yield and quality, a series of meso-scale experiments were performed using 100-l and 900-l reactors. Pasteurization and N 2-sparging replaced autoclaving and boiling for deoxygenating media in the transition from small-scale to pilot-plant reactors. Consecutive 100-L batches using new or recycled media produced ZnS NPs with highly reproducible ~2 nm average crystallite size (ACS) and yields of ~0.5g L -1, similar to small-scale batches.more » The 900-L pilot plant reactor produced ~ 320 g ZnS without process optimization or replacement of used medium; this quantity would be sufficient to form a ZnS thin film with ~120 nm thickness over 0.5 m width 13 km length. At all scales, the bacteria produced significant amounts of acetic, lactic and formic acids, which could be neutralized by the controlled addition of sodium hydroxide without the use of an organic pH buffer, eliminating 98% of the buffer chemical costs. In conclusion, the final NP products were characterized using XRD, ICP-OES, FTIR, DLS, and C/N analyses, which confirmed the growth medium without organic buffer enhanced the ZnS NP properties by reducing carbon and nitrogen surface coatings and supporting better dispersivity with similar ACS.« less

PILOT: optical performance and end-to-end characterisation

NASA Astrophysics Data System (ADS)

Longval, Y.; Misawa, R.; Ade, P.; André, Y.; de Bernardis, P.; Bousquet, F.; Bouzit, M.; Buttice, V.; Charra, M.; Crane, B.; Dubois, J. P.; Engel, C.; Griffin, M.; Hargrave, P.; Leriche, B.; Maestre, S.; Marty, C.; Marty, W.; Masi, S.; Mot, B.; Narbonne, J.; Pajot, F.; Pisano, G.; Ponthieu, N.; Ristorcelli, I.; Rodriguez, L.; Roudil, G.; Simonella, O.; Salatino, M.; Savini, G.; Tucker, C.; Bernard, J.-P.

2017-11-01

PILOT (Polarized Instrument for the Long-wavelength Observations of the Tenuous ISM), is a balloon-borne astronomy experiment dedicated to study the polarization of dust emission from the diffuse ISM in our Galaxy [1]. The observations of PILOT have two major scientific objectives. Firstly, they will allow us to constrain the large-scale geometry of the magnetic field in our Galaxy and to study in details the alignment properties of dust grains with respect to the magnetic field. In this domain, the measurements of PILOT will complement those of the Planck satellite at longer wavelengths. In particular, they will bring information at a better angular resolution, which is critical in crowded regions such as the Galactic plane. They will allow us to better understand how the magnetic field is shaping the ISM material on large scale in molecular clouds, and the role it plays in the gravitational collapse leading to star formation. Secondly, the PILOT observations will allow us to measure for the first time the polarized dust emission towards the most diffuse regions of the sky, where the measurements are the most easily interpreted in terms of the physics of dust. In this particular domain, PILOT will play a role for future CMB missions similar to that played by the Archeops experiment for Planck. The results of PILOT will allow us to gain knowledge about the magnetic properties of dust grains and about the structure of the magnetic field in the diffuse ISM that is necessary to a precise foreground subtraction in future polarized CMB measurements. The PILOT measurements, combined with those of Planck at longer wavelengths, will therefore allow us to further constrain the dust models. The outcome of such studies will likely impact the instrumental and technical choices for the future space missions dedicated to CMB polarization. The PILOT instrument will allow observations in two photometric channels at wavelengths 240 μm and 550 μm, with an angular resolution of a few arcminutes. We will make use of large format bolometer arrays, developed for the PACS instrument on board the Herschel satellite. With 1024 detectors per photometric channel and photometric band optimized for the measurement of dust emission, PILOT is likely to become the most sensitive experiment for this type of measurements. The PILOT experiment will take advantage of the large gain in sensitivity allowed by the use of large format, filled bolometer arrays at frequencies more favorable to the detection of dust emission. This paper presents the optical design, optical characterization and its performance. We begin with a presentation of the instrument and the optical system and then we summarise the main optical tests performed. In section III, we present preliminary end-to-end test results.

Leap motion controlled videogame-based therapy for rehabilitation of elderly patients with subacute stroke: a feasibility pilot study.

PubMed

Iosa, Marco; Morone, Giovanni; Fusco, Augusto; Castagnoli, Marcello; Fusco, Francesca Romana; Pratesi, Luca; Paolucci, Stefano

2015-08-01

The leap motion controller (LMC) is a new optoelectronic system for capturing motion of both hands and controlling a virtual environment. Differently from previous devices, it optoelectronically tracks the fine movements of fingers neither using glows nor markers. This pilot study explored the feasibility of adapting the LMC, developed for videogames, to neurorehabilitation of elderly with subacute stroke. Four elderly patients (71.50 ± 4.51 years old) affected by stroke in subacute phase were enrolled and tested in a cross-over pilot trial in which six sessions of 30 minutes of LMC videogame-based therapy were added on conventional therapy. Measurements involved participation to the sessions, evaluated by means of the Pittsburgh Rehabilitation Participation Scale, hand ability and grasp force evaluated respectively by means of the Abilhand Scale and by means of the dynamometer. Neither adverse effects nor spasticity increments were observed during LMC training. Participation to the sessions was excellent in three patients and very good in one patient during the LMC trial. In this period, patients showed a significantly higher improvement in hand abilities (P = 0.028) and grasp force (P = 0.006). This feasibility pilot study was the first one using leap motion controller for conducting a videogame-based therapy. This study provided a proof of concept that LMC can be a suitable tool even for elderly patients with subacute stroke. LMC training was in fact performed with a high level of active participation, without adverse effects, and contributed to increase the recovery of hand abilities.

Being "SMART" About Adolescent Conduct Problems Prevention: Executing a SMART Pilot Study in a Juvenile Diversion Agency.

PubMed

August, Gerald J; Piehler, Timothy F; Bloomquist, Michael L

2016-01-01

The development of adaptive treatment strategies (ATS) represents the next step in innovating conduct problems prevention programs within a juvenile diversion context. Toward this goal, we present the theoretical rationale, associated methods, and anticipated challenges for a feasibility pilot study in preparation for implementing a full-scale SMART (i.e., sequential, multiple assignment, randomized trial) for conduct problems prevention. The role of a SMART design in constructing ATS is presented. The SMART feasibility pilot study includes a sample of 100 youth (13-17 years of age) identified by law enforcement as early stage offenders and referred for precourt juvenile diversion programming. Prior data on the sample population detail a high level of ethnic diversity and approximately equal representations of both genders. Within the SMART, youth and their families are first randomly assigned to one of two different brief-type evidence-based prevention programs, featuring parent-focused behavioral management or youth-focused strengths-building components. Youth who do not respond sufficiently to brief first-stage programming will be randomly assigned a second time to either an extended parent- or youth-focused second-stage programming. Measures of proximal intervention response and measures of potential candidate tailoring variables for developing ATS within this sample are detailed. Results of the described pilot study will include information regarding feasibility and acceptability of the SMART design. This information will be used to refine a subsequent full-scale SMART. The use of a SMART to develop ATS for prevention will increase the efficiency and effectiveness of prevention programing for youth with developing conduct problems.

Effects of a short duration, high dose contact improvisation dance workshop on Parkinson disease: a pilot study.

PubMed

Marchant, David; Sylvester, Jennifer L; Earhart, Gammon M

2010-10-01

This study explored the feasibility and possible benefits of contact improvisation (CI) as an exercise intervention for individuals with PD. This was an uncontrolled pilot study. Eleven people with PD (H&Y=2.4 ± 0.4) participated in a workshop of 10 1.5-h CI classes over 2 weeks, dancing with previously trained student CI dancers. Measures of disease severity, balance, functional mobility, and gait were compared 1 week before and after the workshop. Participants demonstrated improvements on the Unified Parkinson Disease Rating Scale-Motor Subsection and Berg balance scores, along with increased swing and decreased stance percentages during walking. Backward step length also increased. Participants expressed a high level of enjoyment and interest in taking future CI classes. This pilot study supports the feasibility of CI as an intervention to address mobility limitations associated with PD. Copyright © 2010 Elsevier Ltd. All rights reserved.

Using interpreted large scale aerial photo data to enhance satellite-based mapping and explore forest land definitions

Treesearch

Tracey S. Frescino; Gretchen G. Moisen

2009-01-01

The Interior-West, Forest Inventory and Analysis (FIA), Nevada Photo-Based Inventory Pilot (NPIP), launched in 2004, involved acquisition, processing, and interpretation of large scale aerial photographs on a subset of FIA plots (both forest and nonforest) throughout the state of Nevada. Two objectives of the pilot were to use the interpreted photo data to enhance...

Students' Pilot Laboratory for Homogeneous Chemical Reactor Analysis and Design in Olive Mill Wastewater Treatment

ERIC Educational Resources Information Center

Ochando-Pulido, J. M.

2017-01-01

The Chemical Engineering Department at the University of Granada have endeavored to make a number of high quality experiments to familiarize our students with our latest research and also scale-up of processes. A pilot-scale wastewater treatment plant was set-up to give students a close practical view of the treatments of effluents by-produced in…

DEVELOPMENT AND DEMONSTRATION OF A PILOT SCALE FACILITY FOR FABRICATION AND MARKETING OF LIGHTWEIGHT-COAL COMBUSTION BYPRODUCTS-BASED SUPPORTS AND MINE VENTILATION BLOCKS FOR UNDERGROUND MINES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yoginder P. Chugh

2002-10-01

The overall goal of this program was to develop a pilot scale facility, and design, fabricate, and market CCBs-based lightweight blocks for mine ventilation control devices, and engineered crib elements and posts for use as artificial supports in underground mines to replace similar wooden elements. This specific project was undertaken to (1) design a pilot scale facility to develop and demonstrate commercial production techniques, and (2) provide technical and marketing support to Fly Lite, Inc to operate the pilot scale facility. Fly Lite, Inc is a joint venture company of the three industrial cooperators who were involved in research intomore » the development of CCBs-based structural materials. The Fly-Lite pilot scale facility is located in McLeansboro, Illinois. Lightweight blocks for use in ventilation stoppings in underground mines have been successfully produced and marketed by the pilot-scale facility. To date, over 16,000 lightweight blocks (30-40 pcf) have been sold to the mining industry. Additionally, a smaller width (6-inch) full-density block was developed in August-September 2002 at the request of a mining company. An application has been submitted to Mine Safety and Health Administration for the developed block approval for use in mines. Commercialization of cribs and posts has also been accomplished. Two generations of cribs have been developed and demonstrated in the field. MSHA designated them suitable for use in mines. To date, over 2,000 crib elements have been sold to mines in Illinois. Two generations of posts were also demonstrated in the field and designated as suitable for use in mines by MSHA. Negotiations are currently underway with a mine in Illinois to market about 1,000 posts per year based on a field demonstration in their mine. It is estimated that 4-5 million tons CCBs (F-fly ash or FBC fly ash) may be utilized if the developed products can be commercially implemented in U.S. coal and non-coal mines.« less

Effect of Aromatherapy Massage on Chemotherapy-Induced Peripheral Neuropathic Pain and Fatigue in Patients Receiving Oxaliplatin: An Open Label Quasi-Randomized Controlled Pilot Study.

PubMed

Izgu, Nur; Ozdemir, Leyla; Bugdayci Basal, Fatma

2017-12-02

Patients receiving oxaliplatin may experience peripheral neuropathic pain and fatigue. Aromatherapy massage, a nonpharmacological method, may help to control these symptoms. The aim of this open-label, parallel-group, quasi-randomized controlled pilot study was to investigate the effect of aromatherapy massage on chemotherapy-induced peripheral neuropathic pain and fatigue in patients receiving oxaliplatin. Stratified randomization was used to allocate 46 patients to 2 groups: intervention (n = 22) and control (n = 24). Between week 1 and week 6, participants in the intervention group (IG) received aromatherapy massage 3 times a week. There was no intervention in weeks 7 and 8. The control group (CG) received routine care. Neuropathic pain was identified using the Douleur Neuropathique 4 Questions; severity of painful paresthesia was assessed with the numerical rating scale; fatigue severity was identified with the Piper Fatigue Scale. At week 6, the rate of neuropathic pain was significantly lower in the IG, when compared with the CG. The severity of painful paresthesia based on numerical rating scale in the IG was significantly lower than that in the CG at weeks 2, 4, and 6. At week 8, fatigue severity in the IG was significantly lower when compared with CG (P < .05). Aromatherapy massage may be useful in the management of chemotherapy-induced peripheral neuropathic pain and fatigue. This pilot study suggests that aromatherapy massage may be useful to relieve neuropathic pain and fatigue. However, there is a need for further clinical trials to validate the results of this study.

Modafinil treatment for fatigue in HIV+ patients: a pilot study.

PubMed

Rabkin, Judith G; McElhiney, Martin C; Rabkin, Richard; Ferrando, Stephen J

2004-12-01

Fatigue is widespread among human immunodeficiency virus-positive (HIV+) patients, yet few studies have assessed effective treatments. The authors conducted a pilot study to evaluate the efficacy of modafinil for fatigue in this clinical population. Response was evaluated after a 4-week open-label trial. Data were collected from February 2003 through January 2004. Responders were offered 8 additional weeks of modafinil. Inclusion criteria included written approval from the primary care physician, clinically significant fatigue, current use of anti-retroviral medications, and the absence of treatable medical conditions known to cause fatigue. Exclusion criteria included untreated major depression and current substance abuse. Major outcome measures were the Fatigue Severity Scale, Chalder Fatigue Scale, Hamilton Rating Scale for Depression, Beck Depression Inventory, and neuropsychological tests assessing verbal memory, speed of processing, and executive function. Immunologic and virologic measures were performed at baseline and week 4 to assess safety of treatment. All 30 patients who enrolled completed 4 weeks of treatment; 24 (80%) were rated as responders. Responders showed statistically significant improvement on all measures of fatigue, depressive symptoms, and executive function, while nonresponders did not. Mean values of CD4 cell count and HIV RNA viral load did not change. The most common side effect was headache, followed by irritability and feeling "hyper." This pilot study shows encouraging results for modafinil in alleviation of fatigue in HIV+ patients. In addition, depressive symptoms were substantially reduced. Improvements on measures of verbal memory and executive function were significant, but in the absence of a placebo control, the magnitude of effect due to practice cannot be determined.

Virgil Gus Grissom's Visit to LaRC

NASA Image and Video Library

1963-02-22

Astronaut Virgil "Gus" Grissom at the controls of the Visual Docking Simulator. From A.W. Vogeley, "Piloted Space-Flight Simulation at Langley Research Center," Paper presented at the American Society of Mechanical Engineers 1966 Winter Meeting, New York, NY, November 27-December 1, 1966. "This facility was [later known as the Visual-Optical Simulator.] It presents to the pilot an out-the-window view of his target in correct 6 degrees of freedom motion. The scene is obtained by a television camera pick-up viewing a small-scale gimbaled model of the target." "For docking studies, the docking target picture was projected onto the surface of a 20-foot-diameter sphere and the pilot could, effectively, maneuver into contract. this facility was used in a comparison study with the Rendezvous Docking Simulator - one of the few comparison experiments in which conditions were carefully controlled and a reasonable sample of pilots used. All pilots preferred the more realistic RDS visual scene. The pilots generally liked the RDS angular motion cues although some objected to the false gravity cues that these motions introduced. Training time was shorter on the RDS, but final performance on both simulators was essentially equal. " "For station-keeping studies, since close approach is not required, the target was presented to the pilot through a virtual-image system which projects his view to infinity, providing a more realistic effect. In addition to the target, the system also projects a star and horizon background. "

DESIGN OF A SURFACTANT REMEDIATION FIELD DEMONSTRATION BASED ON LABORATORY AND MODELINE STUDIES

EPA Science Inventory

Surfactant-enhanced subsurface remediation is being evaluated as an innovative technology for expediting ground-water remediation. This paper reports on laboratory and modeling studies conducted in preparation for a pilot-scale field test of surfactant-enhanced subsurface remedia...

METRICS OF PERFORMANCE FOR THE SABRE MICROCOSM STUDY (ABSTRACT ONLY)

EPA Science Inventory

The SABRE (Source Area BioREmediation) project will evaluate accelerated anaerobic bioremediation of chlorinated solvents in areas of high concentration, such as DNAPL source areas. In preparation for a field scale pilot test, a laboratory microcosm study was conducted to provide...

CHARACTERIZING THE MICROBIAL COMMUNITY IN SABRE MICROCOSM STUDIES (ABSTRACT ONLY)

EPA Science Inventory

The SABRE (Source Area BioREmediation) project will evaluate accelerated anaerobic bioremediation of chlorinated solvents in areas of high concentration, such as DNAPL source areas. In preparation for a field scale pilot test, laboratory microcosm and column studies were conducte...

Illness Management & Recovery (IMR) in the Netherlands; a naturalistic pilot study to explore the feasibility of a randomized controlled trial.

PubMed

Roosenschoon, Bert-Jan; van Weeghel, Jaap; Bogaards, Moniek; Deen, Mathijs L; Mulder, Cornelis L

2016-11-09

Illness Management & Recovery (IMR) is a curriculum-based program for people with severe and persistent mental illness. To date, four randomized controlled trials (RCTs) have been published on it. As these produced mixed results, we conducted a pilot study to test the feasibility of conducting a new RCT in a Dutch psychiatric institute. Because our primary objective was to evaluate support for implementing IMR on a broader scale, we examined participant recruitment, client outcomes, and clients' and clinicians' satisfaction. Secondary objectives were to evaluate fidelity, trainers' training and supervision, and to explore program duration, dropout, and client characteristics related to dropout. For reporting, we used the checklist for pilot studies adopted from the CONSORT Statement. This program evaluation included a process-evaluation and an outcome evaluation with a One Group Pre-Posttest Design (N = 81). Interviews and internal reports were used to monitor participant numbers, program duration, dropout, and completers' characteristics. Clients' and clinicians' satisfaction and provision of trainers' training and supervision were assessed through interviews. Fidelity was assessed on the IMR Fidelity Scale; client outcomes were assessed on the IMR scale (client and clinician versions) and the Recovery Markers Questionnaire (RMQ). Eighty-one participants were recruited of 167 people who were assessed for eligibility. Completers and clinicians were satisfied, and scores for completers improved significantly on the IMR scale (clinician version) (d = 0.84) and RMQ (d = 0.52), and not significantly on the IMR scale client version (d = 0.41). Mean fidelity was good, but three groups had only moderate fidelity. Our feasibility criterion for trainers' education and supervision was partly attained. Dropout from treatment was 51 %; female participants and people who scored higher on both IMR-scales at baseline had a significantly lower chance of dropping out. The duration of IMR varied (M = 12.7 months, SD = 2.87). Results suggested that feasibility of conducting an RCT on IMR was good. Special attention is required to fidelity, IMR duration, trainers' education and supervision, and dropout, especially of men. One study limitation was our inability to conduct follow-up measurements of non-completers.

A Piloted Simulator Evaluation of Transport Aircraft Rudder Pedal Force/Feel Characteristics

NASA Technical Reports Server (NTRS)

Stewart, Eric C.

2008-01-01

A piloted simulation study has been conducted in a fixed-base research simulator to assess the directional handling qualities for various rudder pedal feel characteristics for commercial transport airplanes. That is, the effects of static pedal force at maximum pedal travel, breakout force, and maximum pedal travel on handling qualities were studied. An artificial maneuver with a severe lateral wind shear and requiring runway tracking at an altitude of 50 feet in a crosswind was used to fully exercise the rudder pedals. Twelve active airline pilots voluntarily participated in the study and flew approximately 500 maneuvers. The pilots rated the maneuver performance with various rudder pedal feel characteristics using the Cooper- Harper rating scale. The test matrix had 15 unique combinations of the 3 static pedal feel characteristics. A 10-term, second-order equation for the Cooper-Harper pilot rating as a function of the 3 independent pedal feel parameters was fit to the data. The test matrix utilized a Central Composite Design that is very efficient for fitting an equation of this form. The equation was used to produce contour plots of constant pilot ratings as a function of two of the parameters with the third parameter held constant. These contour plots showed regions of good handling qualities as well as regions of degraded handling qualities. In addition, a numerical equation solver was used to predict the optimum parameter values (those with the lowest pilot rating). Quantitative pilot performance data were also analyzed. This analysis found that the peak values of the cross power spectra of the pedal force and heading angle could be used to quantify the tendency toward directional pilot induced oscillations (PIO). Larger peak values of the cross power spectra were correlated with larger (degraded) Cooper-Harper pilot ratings. Thus, the subjective data (Cooper-Harper pilot ratings) were consistent with the objective data (peak values of the cross power spectra).

ASSESSMENT OF MAST IN EUROPEAN PATIENT-CENTERED TELEMEDICINE PILOTS.

PubMed

Ekeland, Anne Granstrøm; Grøttland, Astrid

2015-01-01

Model for ASsessment of Telemedicine Applications (MAST) is a health technology assessment (HTA) inspired framework for assessing the effectiveness and contribution to quality of telemedicine applications based on rigorous, scientific data. This study reports from a study of how it was used and perceived in twenty-one pilots of the European project RENEWING HEALTH (RH). The objectives of RH were to implement large-scale, real-life test beds for the validation and subsequent evaluation of innovative patient-centered telemedicine services. The study is a contribution to the appraisal of HTA methods. A questionnaire was administered for project leaders of the pilots. It included questions about use and usefulness of MAST for (i) preceding considerations, (ii) evaluation of outcomes within seven domains, and (iii) considerations of transferability. Free text spaces allowed for proposals of improvement. The responses covered all pilots. A quantitative summary of use and a qualitative analysis of usefulness were performed. MAST was used and considered useful for pilot evaluations. Challenges included problems to scientifically determine alternative service options and outcome within the seven domains. Proposals for improvement included process studies and adding domains of technological usability, responsible innovation, health literacy, behavior change, caregiver perspectives and motivational issues of professionals. MAST was used according to its structure. Its usefulness in patient centered pilots can be improved by adding new stakeholder groups. Interdependencies between scientific rigor, resources and timeliness should be addressed. Operational options for improvements include process studies, literature reviews and sequential mini-HTAs for identification of areas for more elaborate investigations.

Managing Approach Plate Information Study (MAPLIST): An Information Requirements Analysis of Approach Chart Use

NASA Technical Reports Server (NTRS)

Ricks, Wendell R.; Jonnson, Jon E.; Barry, John S.

1996-01-01

Adequately presenting all necessary information on an approach chart represents a challenge for cartographers. Since many tasks associated with using approach charts are cognitive (e.g., planning the approach and monitoring its progress), and since the characteristic of a successful interface is one that conforms to the users' mental models, understanding pilots' underlying models of approach chart information would greatly assist cartographers. To provide such information, a new methodology was developed for this study that enhances traditional information requirements analyses by combining psychometric scaling techniques with a simulation task to provide quantifiable links between pilots' cognitive representations of approach information and their use of approach information. Results of this study should augment previous information requirements analyses by identifying what information is acquired, when it is acquired, and what presentation concepts might facilitate its efficient use by better matching the pilots' cognitive model of the information. The primary finding in this study indicated that pilots mentally organize approach chart information into ten primary categories: communications, geography, validation, obstructions, navigation, missed approach, final items, other runways, visibility requirement, and navigation aids. These similarity categories were found to underlie the pilots' information acquisitions, other mental models, and higher level cognitive processes that are used to accomplish their approach and landing tasks.

Preliminary validation of the Satisfaction With Decision scale with depressed primary care patients

PubMed Central

Wills, Celia E.; Holmes‐Rovner, Margaret

2003-01-01

Abstract Objective To conduct a preliminary validation of the Satisfaction With Decision (SWD) scale with depressed primary care patients. Design  Cross‐sectional observational pilot study using a postal survey. Setting and participants  Depressed primary care patients (n = 97) who recently had made a new decision about antidepressant medication use completed surveys regarding their treatment decisions. Main variables  Measures included patient‐reported satisfaction with decision, decisional conflict, knowledge about depression and treatment, decision involvement, pain and health status, antidepressant medication efficacy, and satisfaction with health services. Results  The SWD scale had good internal consistency reliability (α = 0.85). Evidence for construct validity was confirmed via a hypothesized pattern of relationships between the SWD scale and other measures. Decision satisfaction was associated with several issues of relevance for designing patient‐centred decision support interventions: (1) knowledge about depression and treatment; (2) involvement in health‐related decisions; and (3) aiding evaluation of trade‐offs among pros and cons of treatment. Conclusions  The results of this pilot study show that the SWD scale appears to be a psychometrically sound and practical measure for research with this population. Additional research is needed on the theoretical nature of decision satisfaction and developing and testing patient‐centred decision support interventions for depression treatment. PMID:12752743

Farm-scale testing of soybean peroxidase and calcium peroxide for surficial swine manure treatment and mitigation of odorous VOCs, ammonia and hydrogen sulfide

USDA-ARS?s Scientific Manuscript database

The swine industry, regulatory agencies, and the public are interested in farm-tested methods for controlling gaseous emissions from swine barns. In earlier lab- and pilot-scale studies, a renewable catalyst consisting of soybean peroxidase (SBP) mixed with calcium peroxide was found to be effective...

Combined Use of Self-Efficacy Scale for Oral Health Behaviour and Oral Health Questionnaire: A Pilot Study

ERIC Educational Resources Information Center

Soutome, Sakiko; Kajiwara, Kazumi; Oho, Takahiko

2012-01-01

Objective: To examine whether the combined use of a task-specific self-efficacy scale for oral health behaviour (SEOH) and an oral health questionnaire (OHQ) would be useful for evaluating subjects' behaviours and cognitions. Design: Questionnaires. Methods: One hundred and eighty-five students completed the SEOH and OHQ. The 30-item OHQ uses a…

Examination of the Psychometric Properties of the Environmental School Transition Anxiety Scale

ERIC Educational Resources Information Center

Loke, Stephen W.; Lowe, Patricia A.

2013-01-01

A pilot study was conducted to examine the psychometric properties of the Environmental School Transition Anxiety Scale (E-STAS) with a sample of 220 fourth- to sixth-grade students who were about to or had completed their school transition. The results of an exploratory factor analysis (EFA) of the students' responses on the E-STAS produced a…

Development of the Language Subtest in a Developmental Assessment Scale to Identify Chinese Preschool Children with Special Needs

ERIC Educational Resources Information Center

Wong, Anita M. -Y.; Leung, Cynthia; Siu, Elaine K. -L.; Lam, Catherine C. -C.; Chan, Grace P. -S.

2011-01-01

This study reports on the development of the language subtest in the Preschool Developmental Assessment Scale (PDAS) for Cantonese-Chinese speaking children. A pilot pool of 158 items covering the two language modalities and the three language domains was developed. This initial item set was subsequently revised based on Rasch analyses of data…

Changes in Attitudes, Knowledge and Behavior Associated with Implementing a Comprehensive School Health Program in a Province of China

ERIC Educational Resources Information Center

Aldinger, Carmen; Zhang, Xin-Wei; Liu, Li-Qun; Pan, Xue-Dong; Yu, Sen-Hai; Jones, Jack; Kass, Jared

2008-01-01

After successful pilot projects, Zhejiang Province, China, decided to systematically scale-up health promoting schools (HPS) over the entire province of 47 million. This study describes the interventions and self-reported changes in attitudes, knowledge and behavior during the first phase of scaling-up. Group interviews were conducted with a…

Development of Physics Attitude Scale (PAS): An Instrument to Measure Students' Attitudes toward Physics

ERIC Educational Resources Information Center

Kaur, Daisy; Zhao, Yi

2017-01-01

The present study is focused on the detailed description of Physics Attitude Scale (PAS) to measure students' attitudes toward physics. The development of this new instrument involved extensive interviews with both the experts as well as the students. This was followed by expert reviews and pilot testing of the instrument. The duly revised draft…

The Making of a Self-Neglect Severity Scale

NASA Technical Reports Server (NTRS)

Smith, Scott M.; Dyer, C. B.; Pavlik, V. N.; Kelly, P. A.; Lee, J.; Doody, R. S.; Regev, C.; Pickens, C.; Burnett, J.

2006-01-01

Research in elder self-neglect has lagged behind that of other forms of mistreatment, despite the fact that self-neglect is the most common allegation reported to Adult Protective Service agencies throughout the US. The lack of a gold-standard to measure self-neglect has hampered efforts to study this phenomenon. Researchers designed the Self-neglect Severity Scale (SSS) based on interviews with Adult Protective Service workers and a national expert panel. The SSS is based on observation and interview and is administered in the home to include an environmental assessment. It was piloted, extensively field tested and then revised. The CREST SSS was developed using survey data and consultation with experts in the field. This instrument utilizes observer ratings, interview responses, and assesses subjects physical and environmental domains. It also assesses functional status as it relates to health and safety issues. After field and pilot testing the SSS was finalized and is currently undergoing reliability and validity testing. The CREST SSS was developed as a state scale to provide a common language for describing cases of self-neglect. It is the first self-neglect severity scale available to researchers. If found to be both reliable and valid it can be used in future intervention studies.

The making of a self-neglect severity scale.

PubMed

Dyer, Carmel Bitondo; Kelly, P Adam; Pavlik, Valory N; Lee, Jessica; Doody, Rachelle S; Regev, Tziona; Pickens, Sabrina; Burnett, Jason; Smith, Scott M

2006-01-01

Research in elder self-neglect has lagged behind that of other forms of mistreatment, despite the fact that self-neglect is the most common allegation reported to Adult Protective Service agencies throughout the US. The lack of a gold standard to measure self-neglect has hampered efforts to study this phenomenon. Researchers designed the Self-Neglect Severity Scale (SSS) based on interviews with Adult Protective Service workers and a national expert panel. The SSS is based on observation and interview and is administered in the home to include an environmental assessment. It was piloted, extensively field tested and then revised. The CREST SSS was developed using survey data and consultation with experts in the field. This instrument utilizes observer ratings, interview responses, and assesses subjects' physical and environmental domains. It also assesses functional status as it relates to health and safety issues. After field and pilot testing, the SSS was finalized and is currently undergoing reliability and validity testing. The CREST SSS was developed as a state scale to provide a common language for describing cases of self-neglect. It is the first self-neglect severity scale available to researchers. If found to be both reliable and valid, it may be used in future intervention studies.

Pilot-scale data provide enhanced estimates of the life cycle energy and emissions profile of algae biofuels produced via hydrothermal liquefaction.

PubMed

Liu, Xiaowei; Saydah, Benjamin; Eranki, Pragnya; Colosi, Lisa M; Greg Mitchell, B; Rhodes, James; Clarens, Andres F

2013-11-01

Life cycle assessment (LCA) has been used widely to estimate the environmental implications of deploying algae-to-energy systems even though no full-scale facilities have yet to be built. Here, data from a pilot-scale facility using hydrothermal liquefaction (HTL) is used to estimate the life cycle profiles at full scale. Three scenarios (lab-, pilot-, and full-scale) were defined to understand how development in the industry could impact its life cycle burdens. HTL-derived algae fuels were found to have lower greenhouse gas (GHG) emissions than petroleum fuels. Algae-derived gasoline had significantly lower GHG emissions than corn ethanol. Most algae-based fuels have an energy return on investment between 1 and 3, which is lower than petroleum biofuels. Sensitivity analyses reveal several areas in which improvements by algae bioenergy companies (e.g., biocrude yields, nutrient recycle) and by supporting industries (e.g., CO2 supply chains) could reduce the burdens of the industry. Copyright © 2013 Elsevier Ltd. All rights reserved.

Pilot-Scale Laboratory Instruction for Chemical Engineering: The Specific Case of the Pilot-Unit Leading Group

ERIC Educational Resources Information Center

Billet, Anne-Marie; Camy, Severine; Coufort-Saudejaud, Carole

2010-01-01

This paper presents an original approach for Chemical Engineering laboratory teaching that is currently applied at INP-ENSIACET (France). This approach, referred to as "pilot-unit leading group" is based on a partial management of the laboratories by the students themselves who become temporarily in charge of one specific laboratory. In…

[Spanish translation and cross-cultural adaptation of the ARMS-scale for measuring medication adherence in polypathological patients].

PubMed

González-Bueno, Javier; Calvo-Cidoncha, Elena; Sevilla-Sánchez, Daniel; Espaulella-Panicot, Joan; Codina-Jané, Carles; Santos-Ramos, Bernardo

2017-10-01

Translate the ARMS scale into Spanish ensuring cross-cultural equivalence for measuring medication adherence in polypathological patients. Translation, cross-cultural adaptation and pilot testing. Secondary hospital. (i)Forward and blind-back translations followed by cross-cultural adaptation through qualitative methodology to ensure conceptual, semantic and content equivalence between the original scale and the Spanish version. (ii)Pilot testing in non-institutionalized polypathological patients to assess the instrument for clarity. The Spanish version of the ARMS scale has been obtained. Overall scores from translators involved in forward and blind-back translations were consistent with a low difficulty for assuring conceptual equivalence between both languages. Pilot testing (cognitive debriefing) in a sample of 40 non-institutionalized polypathological patients admitted to an internal medicine department of a secondary hospital showed an excellent clarity. The ARMS-e scale is a Spanish-adapted version of the ARMS scale, suitable for measuring adherence in polypathological patients. Its structure enables a multidimensional approach of the lack of adherence allowing the implementation of individualized interventions guided by the barriers detected in every patient. Copyright © 2017 Elsevier España, S.L.U. All rights reserved.

Establishment and assessment of a novel cleaner production process of corn grain fuel ethanol.

PubMed

Wang, Ke; Zhang, Jianhua; Tang, Lei; Zhang, Hongjian; Zhang, Guiying; Yang, Xizhao; Liu, Pei; Mao, Zhonggui

2013-11-01

An integrated corn ethanol-methane fermentation system was proposed to solve the problem of stillage handling, where thin stillage was treated by anaerobic digestion and then reused to make mash for the following ethanol fermentation. This system was evaluated at laboratory and pilot scale. Anaerobic digestion of thin stillage ran steadily with total chemical oxygen demand removal efficiency of 98% at laboratory scale and 97% at pilot scale. Ethanol production was not influenced by recycling anaerobic digestion effluent at laboratory and pilot scale. Compared with dried distillers' grains with solubles produced in conventional process, dried distillers' grains in the proposed system exhibited higher quality because of increased protein concentration and decreased salts concentration. Energetic assessment indicated that application of this novel process enhanced the net energy balance ratio from 1.26 (conventional process) to 1.76. In conclusion, the proposed system possessed technical advantage over the conventional process for corn fuel ethanol production. Copyright © 2013 Elsevier Ltd. All rights reserved.

Changes in the Structure and Function of Microbial Communities in Drinking Water Treatment Bioreactors upon Addition of Phosphorus▿ †

PubMed Central

Li, Xu; Upadhyaya, Giridhar; Yuen, Wangki; Brown, Jess; Morgenroth, Eberhard; Raskin, Lutgarde

2010-01-01

Phosphorus was added as a nutrient to bench-scale and pilot-scale biologically active carbon (BAC) reactors operated for perchlorate and nitrate removal from contaminated groundwater. The two bioreactors responded similarly to phosphorus addition in terms of microbial community function (i.e., reactor performance), while drastically different responses in microbial community structure were detected. Improvement in reactor performance with respect to perchlorate and nitrate removal started within a few days after phosphorus addition for both reactors. Microbial community structures were evaluated using molecular techniques targeting 16S rRNA genes. Clone library results showed that the relative abundance of perchlorate-reducing bacteria (PRB) Dechloromonas and Azospira in the bench-scale reactor increased from 15.2% and 0.6% to 54.2% and 11.7% after phosphorus addition, respectively. Real-time quantitative PCR (qPCR) experiments revealed that these increases started within a few days after phosphorus addition. In contrast, after phosphorus addition, the relative abundance of Dechloromonas in the pilot-scale reactor decreased from 7.1 to 0.6%, while Zoogloea increased from 17.9 to 52.0%. The results of this study demonstrated that similar operating conditions for bench-scale and pilot-scale reactors resulted in similar contaminant removal performances, despite dramatically different responses from microbial communities. These findings suggest that it is important to evaluate the microbial community compositions inside bioreactors used for drinking water treatment, as they determine the microbial composition in the effluent and impact downstream treatment requirements for drinking water production. This information could be particularly relevant to drinking water safety, if pathogens or disinfectant-resistant bacteria are detected in the bioreactors. PMID:20889793

What can a pilot congestive heart failure disease management program tell us about likely return on investment?: A case study from a program offered to federal employees.

PubMed

vanVonno, Catherine J; Ozminkowski, Ronald J; Smith, Mark W; Thomas, Eileen G; Kelley, Doniece; Goetzel, Ron; Berg, Gregory D; Jain, Susheel K; Walker, David R

2005-12-01

In 1999, the Blue Cross and Blue Shield Federal Employee Program (FEP) implemented a pilot disease management program to manage congestive heart failure (CHF) among members. The purpose of this project was to estimate the financial return on investment in the pilot CHF program, prior to a full program rollout. A cohort of 457 participants from the state of Maryland was matched to a cohort of 803 nonparticipants from a neighboring state where the CHF program was not offered. Each cohort was followed for 12 months before the program began and 12 months afterward. The outcome measures of primary interest were the differences over time in medical care expenditures paid by FEP and by all payers. Independent variables included indicators of program participation, type of heart disease, comorbidity measures, and demographics. From the perspective of the funding organization (FEP), the estimated return on investment for the pilot CHF disease management program was a savings of $1.08 in medical expenditure for every dollar spent on the program. Adding savings to other payers as well, the return on investment was a savings of $1.15 in medical expenditures per dollar spent on the program. The amount of savings depended upon CHF risk levels. The value of a pilot initiative and evaluation is that lessons for larger-scale efforts can be learned prior to full-scale rollout.

Field Testing of a Wet FGD Additive for Enhanced Mercury Control

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gary Blythe; MariJon Owens

2007-12-31

This document is the final report for DOE-NETL Cooperative Agreement DE-FC26-04NT42309, 'Field Testing of a Wet FGD Additive'. The objective of the project has been to demonstrate the use of two flue gas desulfurization (FGD) additives, Evonik Degussa Corporation's TMT-15 and Nalco Company's Nalco 8034, to prevent the re-emission of elemental mercury (Hg{sup 0}) in flue gas exiting wet FGD systems on coal-fired boilers. Furthermore, the project was intended to demonstrate whether such additives can be used to precipitate most of the mercury (Hg) removed in the wet FGD system as a fine salt that can be separated from themore » FGD liquor and bulk solid byproducts for separate disposal. The project involved pilot- and full-scale tests of the additives in wet FGD absorbers. The tests were intended to determine required additive dosages to prevent Hg{sup 0} re-emissions and to separate mercury from the normal FGD byproducts for three coal types: Texas lignite/Powder River Basin (PRB) coal blend, high-sulfur Eastern bituminous coal, and low-sulfur Eastern bituminous coal. The project team consists of URS Group, Inc., EPRI, Luminant Power (was TXU Generation Company LP), Southern Company, IPL (an AES company), Evonik Degussa Corporation and the Nalco Company. Luminant Power provided the Texas lignite/PRB co-fired test site for pilot FGD tests and project cost sharing. Southern Company provided the low-sulfur Eastern bituminous coal host site for wet scrubbing tests, the pilot- and full-scale jet bubbling reactor (JBR) FGD systems tested, and project cost sharing. IPL provided the high-sulfur Eastern bituminous coal full-scale FGD test site and cost sharing. Evonik Degussa Corporation provided the TMT-15 additive, and the Nalco Company provided the Nalco 8034 additive. Both companies also supplied technical support to the test program as in-kind cost sharing. The project was conducted in six tasks. Of the six tasks, Task 1 involved project planning and Task 6 involved management and reporting. The other four tasks involved field testing on FGD systems, either at pilot or full scale. These four tasks included: Task 2 - Pilot Additive Testing in Texas Lignite Flue Gas; Task 3 - Full-scale FGD Additive Testing in High-sulfur Eastern Bituminous Flue Gas; Task 4 - Pilot Wet Scrubber Additive Tests at Plant Yates; and Task 5 - Full-scale Additive Tests at Plant Yates. The pilot-scale tests were completed in 2005 and the full-scale test using high-sulfur coal was completed in 2006; only the TMT-15 additive was tested in these efforts. The Task 5 full-scale additive tests conducted at Southern Company's Plant Yates Unit 1 were completed in 2007, and both the TMT-15 and Nalco 8034 additives were tested.« less

Anaerobic Digestion of Laminaria japonica Waste from Industrial Production Residues in Laboratory- and Pilot-Scale

PubMed Central

Barbot, Yann Nicolas; Thomsen, Claudia; Thomsen, Laurenz; Benz, Roland

2015-01-01

The cultivation of macroalgae to supply the biofuel, pharmaceutical or food industries generates a considerable amount of organic residue, which represents a potential substrate for biomethanation. Its use optimizes the total resource exploitation by the simultaneous disposal of waste biomaterials. In this study, we explored the biochemical methane potential (BMP) and biomethane recovery of industrial Laminaria japonica waste (LJW) in batch, continuous laboratory and pilot-scale trials. Thermo-acidic pretreatment with industry-grade HCl or industrial flue gas condensate (FGC), as well as a co-digestion approach with maize silage (MS) did not improve the biomethane recovery. BMPs between 172 mL and 214 mL g−1 volatile solids (VS) were recorded. We proved the feasibility of long-term continuous anaerobic digestion with LJW as sole feedstock showing a steady biomethane production rate of 173 mL g−1 VS. The quality of fermentation residue was sufficient to serve as biofertilizer, with enriched amounts of potassium, sulfur and iron. We further demonstrated the upscaling feasibility of the process in a pilot-scale system where a CH4 recovery of 189 L kg−1 VS was achieved and a biogas composition of 55% CH4 and 38% CO2 was recorded. PMID:26393620

Application of response surface methodology (RSM) for optimisation of COD, NH3-N and 2,4-DCP removal from recycled paper wastewater in a pilot-scale granular activated carbon sequencing batch biofilm reactor (GAC-SBBR).

PubMed

Muhamad, Mohd Hafizuddin; Sheikh Abdullah, Siti Rozaimah; Mohamad, Abu Bakar; Abdul Rahman, Rakmi; Hasan Kadhum, Abdul Amir

2013-05-30

In this study, the potential of a pilot-scale granular activated carbon sequencing batch biofilm reactor (GAC-SBBR) for removing chemical oxygen demand (COD), ammoniacal nitrogen (NH3-N) and 2,4-dichlorophenol (2,4-DCP) from recycled paper wastewater was assessed. For this purpose, the response surface methodology (RSM) was employed, using a central composite face-centred design (CCFD), to optimise three of the most important operating variables, i.e., hydraulic retention time (HRT), aeration rate (AR) and influent feed concentration (IFC), in the pilot-scale GAC-SBBR process for recycled paper wastewater treatment. Quadratic models were developed for the response variables, i.e., COD, NH3-N and 2,4-DCP removal, based on the high value (>0.9) of the coefficient of determination (R(2)) obtained from the analysis of variance (ANOVA). The optimal conditions were established at 750 mg COD/L IFC, 3.2 m(3)/min AR and 1 day HRT, corresponding to predicted COD, NH3-N and 2,4-DCP removal percentages of 94.8, 100 and 80.9%, respectively. Copyright © 2013 Elsevier Ltd. All rights reserved.

Solar photocatalytic treatment of trimethoprim in four environmental matrices at a pilot scale: transformation products and ecotoxicity evaluation.

PubMed

Michael, I; Hapeshi, E; Osorio, V; Perez, S; Petrovic, M; Zapata, A; Malato, S; Barceló, D; Fatta-Kassinos, D

2012-07-15

The pilot-scale solar degradation of trimethoprim (TMP) in different water matrices (demineralized water: DW, simulated natural freshwater: SW; simulated wastewater: SWW; and real effluent: RE) was investigated in this study. DOC removal was lower in the case of SW compared to DW, which can be attributed to the presence of inorganic anions which may act as scavengers of the HO·. Furthermore, the presence of organic carbon and higher salt content in SWW and RE led to lower mineralization per dose of hydrogen peroxide compared to DW and SW. Toxicity assays in SWW and RE were also performed indicating that toxicity is attributed to the compounds present in RE and their by-products formed during solar Fenton treatment and not to the intermediates formed by the oxidation of TMP. A large number of compounds generated by the photocatalytic transformation of TMP were identified by UPLC-QToF/MS. The degradation pathway revealed differences among the four matrices; however hydroxylation, demethylation and cleavage reactions were observed in all matrices. To the best of our knowledge this is the first time that TMP degradation products have been identified by adopting a solar Fenton process at a pilot-scale set-up, using four different aqueous matrices. Copyright © 2012 Elsevier B.V. All rights reserved.

[Pilot-scale cultivation of Spirulina plantensis with digested piggery wastewater ].

PubMed

Guo, Qing-qing; Liu, Rui; Luo, Jin-fei; Wang, Gen-rong; Chen, Lii-jun; Liu, Xiao

2014-09-01

The swine waste pretreated with coagulation sedimentation was used for the outdoor pilot-scale cultivation of Spirulina platensis isolated from digested piggery wastewater (DPW) in a raceway pond. The growth of S. platensis and removal of nitrogen/ phosphorus were studied, moreover, the conversion efficiency of total nitrogen (TN) or total phosphorus (TP) from DPW to S. platensis was calculated. On this basis, the existing problems and countermeasures during outdoor pilot-scale culture were analyzed and summarized combined with the laboratory research. We conducted 6 batches culture experiments, only 3 of which could reach the S. platensis harvest requirements (D560 >0. 8). Meanwhile, the 3 successful batches achieved removal of COD, ammonia nitrogen, TN, TP with corresponding 28. 6% -48. 5% , 0.4% -48. 5% , 41. 8% -48. 6% , 14. 3% -94. 5% , and the conversion efficiency of TN or TP from DPW to S. platensis reached 12. 1% -98. 5% , 21.2% -83.7% , respectively. High concentration of ammonia nitrogen and insect attack of remaining egg hatching in the pretreated swine waste were the main factors to cause the slow-growing of the 3 batches of S. platensis. Therefore, it is highly necessary for the removal of ammonia nitrogen with biological treatment technology and insect eggs with membrane to achieve a stable high productivity.

Pretreatment of corn stover by low moisture anhydrous ammonia (LMMA) in a pilot-scale reactor and bioconversion to fuel ethanol and industrial chemicals

USDA-ARS?s Scientific Manuscript database

Corn stover (CS) adjusted to 50%, 66% and 70% moisture was pretreated by the low moisture anhydrous ammonia (LMAA) process in a pilot-scale ammoniation reactor. After ammoniation, the 70% moisture CS was treated at 90 degree C and 100 degree C whereas the others were treated at 90 degree C only. The...

Scaled Composites' Doug Shane examines the screen of his ground control station during tests in New Mexico. Shane used this configuration as the ground control station to remotely pilot the Proteus aircraft during a NASA sponsored series of tests.

NASA Image and Video Library

2002-03-13

Scaled Composites' Doug Shane examines the screen of his ground control station during tests in New Mexico. Shane used this configuration as the ground control station to remotely pilot the Proteus aircraft during a NASA sponsored series of tests.

Initial test of large panels of structural flakeboard from southern hardwoods

Treesearch

Eddie W. Price

1975-01-01

A strong structural exterior flakeboard from mixed southern hardwoods has been developed on a laboratory scale; the problem is transfer of the technique to pilot-plant scale in the manufacture of 4- by 8-ft panels. From the pilot-plant trial here reported, it is concluded that a specific platen pressure of at least 575 psi and a hot press closing time of about 45...

Methodological approaches to conducting pilot and proof tests on reverse-osmosis systems: Results of comparative studies

NASA Astrophysics Data System (ADS)

Panteleev, A. A.; Bobinkin, V. V.; Larionov, S. Yu.; Ryabchikov, B. E.; Smirnov, V. B.; Shapovalov, D. A.

2017-10-01

When designing large-scale water-treatment plants based on reverse-osmosis systems, it is proposed to conduct experimental-industrial or pilot tests for validated simulation of the operation of the equipment. It is shown that such tests allow establishing efficient operating conditions and characteristics of the plant under design. It is proposed to conduct pilot tests of the reverse-osmosis systems on pilot membrane plants (PMPs) and test membrane plants (TMPs). The results of a comparative experimental study of pilot and test membrane plants are exemplified by simulating the operating parameters of the membrane elements of an industrial plant. It is concluded that the reliability of the data obtained on the TMP may not be sufficient to design industrial water-treatment plants, while the PMPs are capable of providing reliable data that can be used for full-scale simulation of the operation of industrial reverse-osmosis systems. The test membrane plants allow simulation of the operating conditions of individual industrial plant systems; therefore, potential areas of their application are shown. A method for numerical calculation and experimental determination of the true selectivity and the salt passage are proposed. An expression has been derived that describes the functional dependence between the observed and true salt passage. The results of the experiments conducted on a test membrane plant to determine the true value of the salt passage of a reverse-osmosis membrane are exemplified by magnesium sulfate solution at different initial operating parameters. It is shown that the initial content of a particular solution component has a significant effect on the change in the true salt passage of the membrane.

A Randomized Controlled Exploratory Pilot Study to Evaluate the Effect of Rotigotine Transdermal Patch on Parkinson's Disease-Associated Chronic Pain.

PubMed

Rascol, Olivier; Zesiewicz, Theresa; Chaudhuri, K Ray; Asgharnejad, Mahnaz; Surmann, Erwin; Dohin, Elisabeth; Nilius, Sigrid; Bauer, Lars

2016-07-01

Pain is a troublesome nonmotor symptom of Parkinson's disease (PD). This double-blind exploratory pilot study (NCT01744496) was the first to specifically investigate the effect of a dopamine agonist on PD-associated pain as primary outcome. Patients with advanced PD (ie, receiving levodopa) and at least moderate PD-associated chronic pain (≥3 months, ≥4 points on 11-point Likert pain scale) were randomized to rotigotine (optimal/maximum dose ≤16 mg/24h) or placebo and maintained for 12 weeks. Primary efficacy variable was change in pain severity (Likert pain scale) from baseline to end of maintenance. Secondary variables included percentage of responders (≥2-point Likert pain scale reduction), King's PD Pain Scale (KPPS) domains, and PD Questionnaire (PDQ-8). Statistical analyses were exploratory. Of 68 randomized patients, 60 (rotigotine, 30; placebo, 30) were evaluable for efficacy. A numerical improvement in pain was observed in favor of rotigotine (Likert pain scale: least-squares mean [95%CI] treatment difference, -0.76 [-1.87 to 0.34]; P = .172), and proportion of responders was 18/30 (60%) rotigotine vs 14/30 (47%) placebo. An ∼2-fold numerical improvement in KPPS domain "fluctuation-related pain" was observed with rotigotine vs placebo. Rotigotine improved PDQ-8 vs placebo (-8.01 [-15.56 to -0.46]; P = .038). These results suggest rotigotine may improve PD-associated pain; a large-scale confirmatory study is needed. © 2015, The American College of Clinical Pharmacology.

Vermicomposting of a lignocellulosic waste from olive oil industry: a pilot scale study.

PubMed

Benítez, E; Sainz, H; Melgar, R; Nogales, R

2002-04-01

The vermicomposting with Eisenia andrei of dry olive cake, a lignocellulosic waste produced during the extraction of olive oil, either alone or mixed with municipal biosolids, was studied in a nine-month pilot scale experiment. Number and biomass of earthworms and enzyme activities were periodically monitored and relevant properties of the final products were determined. In the assayed substrates, the total biomass of earthworms increased at the end of the experimental period between 9 and 12-fold respectively in comparison with the earthworm biomass initially inoculated. The increase in hydrolytic enzymes and overall microbial activity during the vermicomposting process indicated the biodegradation of the olive cake and resulted in the disappearance of the initial phytotoxicity of the substrate. However, the recalcitrant lignocellulosic nature of the dry olive cake prevented suitable humification during the vermicomposting process. For this reason, in addition to organic amendments, other management procedures should be considered.

Biological Ammonia Removal: From Theory to Case Studies in 20 Minutes

EPA Science Inventory

This presentation documents the results of two pilot-scale treatment studies, in Ohio and Iowa, that investigated the biological removal of ammonia from ground water. Influent ammonia concentrations in the Ohio and Iowa studies averaged 1.3 and 3.3 mg/L - N, respectively. Both ...

Students' Perceptions of an Internship Experience in China: A Pilot Study

ERIC Educational Resources Information Center

He, Yunjuan; Qin, Xizhen

2017-01-01

This small-scale study reported American students' perception of the effect of their internship conducted in a study abroad program on their development of Chinese language proficiency, intercultural competence, and professional knowledge. The results indicate that a self-evaluated successful internship allows interns with intermediate-level…

Identifying Students Difficulties in Understanding Concepts Pertaining to Cell Water Relations: An Exploratory Study.

ERIC Educational Resources Information Center

Friedler, Y.; And Others

This study identified students' conceptual difficulties in understanding concepts and processes associated with cell water relationships (osmosis), determined possible reasons for these difficulties, and pilot-tested instruments and research strategies for a large scale comprehensive study. Research strategies used included content analysis of…

Comparison of bacteriophage and enteric virus removal in pilot scale activated sludge plants.

PubMed

Arraj, A; Bohatier, J; Laveran, H; Traore, O

2005-01-01

The aim of this experimental study was to determine comparatively the removal of two types of bacteriophages, a somatic coliphage and an F-specific RNA phage and of three types of enteric viruses, hepatitis A virus (HAV), poliovirus and rotavirus during sewage treatment by activated sludge using laboratory pilot plants. The cultivable simian rotavirus SA11, the HAV HM 175/18f cytopathic strain and poliovirus were quantified by cell culture. The bacteriophages were quantified by plaque formation on the host bacterium in agar medium. In each experiment, two pilots simulating full-scale activated sludge plants were inoculated with viruses at known concentrations, and mixed liquor and effluent samples were analysed regularly. In the mixed liquor, liquid and solid fractions were analysed separately. The viral behaviour in both the liquid and solid phases was similar between pilots of each experiment. Viral concentrations decreased rapidly following viral injection in the pilots. Ten minutes after the injections, viral concentrations in the liquid phase had decreased from 1.0 +/- 0.4 log to 2.2 +/- 0.3 log. Poliovirus and HAV were predominantly adsorbed on the solid matters of the mixed liquor while rotavirus was not detectable in the solid phase. In our model, the estimated mean log viral reductions after 3-day experiment were 9.2 +/- 0.4 for rotavirus, 6.6 +/- 2.4 for poliovirus, 5.9 +/- 3.5 for HAV, 3.2 +/- 1.2 for MS2 and 2.3 +/- 0.5 for PhiX174. This study demonstrates that the pilots are useful models to assess the removal of infectious enteric viruses and bacteriophages by activated sludge treatment. Our results show the efficacy of the activated sludge treatment on the five viruses and suggest that coliphages could be an acceptable indicator of viral removal in this treatment system.

Integration of altitude and airspeed information into a primary flight display via moving-tape formats: Evaluation during random tracking task

NASA Technical Reports Server (NTRS)

Abbott, Terence S.; Nataupsky, Mark; Steinmetz, George G.

1987-01-01

A ground-based aircraft simulation study was conducted to determine the effects on pilot preference and performance of integrating airspeed and altitude information into an advanced electronic primary flight display via moving-tape (linear moving scale) formats. Several key issues relating to the implementation of moving-tape formats were examined in this study: tape centering, tape orientation, and trend information. The factor of centering refers to whether the tape was centered about the actual airspeed or altitude or about some other defined reference value. Tape orientation refers to whether the represented values are arranged in descending or ascending order. Two pilots participated in this study, with each performing 32 runs along seemingly random, previously unknown flight profiles. The data taken, analyzed, and presented consisted of path performance parameters, pilot-control inputs, and electrical brain response measurements.

Practical considerations for transitioning early childhood interventions to scale: lessons from the Saving Brains portfolio.

PubMed

Radner, James M; Ferrer, Marvin J S; McMahon, Dominique; Shankar, Anuraj H; Silver, Karlee L

2018-05-01

Small pilot studies of young children have frequently shown promise, but very few have been successfully scaled to the regional or national levels. How can we ensure that these promising approaches move from a suite of pilots to full-scale implementation that can deliver sustainable impact for hundreds of millions of children? To elucidate concrete lessons learned and suggestions on accelerating the transition to impact at scale, we reviewed the Saving Brains portfolio to better understand three points: (1) the extent to which useful signals of impact could be extracted from data at the seed phase, (2) the ways in which innovators (project leaders) were approaching human resource challenges critical for scaling, and (3) the multisector diversity of the portfolio and the way innovators entered partnerships. The findings suggest key considerations for transitioning early childhood development interventions to scale and sustainability: strong entrepreneurial leadership, rigorous measurement and active use of data in support of adaptive learning, and champions acting at subnational levels. Together, these can enable flexible, iterative learning that can make the scaling process an opportunity to increase the level of benefit each child receives from an intervention. © 2018 The Authors. Annals of the New York Academy of Sciences published by Wiley Periodicals, Inc. on behalf of The New York Academy of Sciences.

Aerobic nonaseptic growth of Verticillium on coffee waste waters and cane blackstrap molasses at a pilot plant scale

DOE Office of Scientific and Technical Information (OSTI.GOV)

Espinosa, R.; Maldonado, O.; Menchu, J.F.

1977-01-01

An evaluation is made of the pilot plant studies on the biosynthesis of Verticillium sp. both on coffee waste waters and blackstrap molasses. The purpose of the study was two-fold: the first to produce a filamentous fungi as a source of protein and the second to alleviate the serious water pollution resulting from the processing of coffee berries. The molasses was studied as an alternative medium to enable year-round operation of the plant since coffee is a seasonal crop. The results indicated that the growth of Verticillium is technically feasible in a batch operation. (JSR)

Performance of granular activated carbon to remove micropollutants from municipal wastewater-A meta-analysis of pilot- and large-scale studies.

PubMed

Benstoem, Frank; Nahrstedt, Andreas; Boehler, Marc; Knopp, Gregor; Montag, David; Siegrist, Hansruedi; Pinnekamp, Johannes

2017-10-01

For reducing organic micropollutants (MP) in municipal wastewater effluents, granular activated carbon (GAC) has been tested in various studies. We did systematic literature research and found 44 studies dealing with the adsorption of MPs (carbamazepine, diclofenac, sulfamethoxazole) from municipal wastewater on GAC in pilot- and large-scale plants. Within our meta-analysis we plot the bed volumes (BV [m 3 water /m 3 GAC ]) until the breakthrough criterion of MP-BV20% was reached, dependent on potential relevant parameters (empty bed contact time EBCT, influent DOC DOC 0 and manufacturing method). Moreover, we performed statistical tests (ANOVAs) to check the results for significance. Single adsorbers operating time differs i.e. by 2500% until breakthrough of diclofenac-BV20% was reached (800-20,000 BV). There was still elimination of the "very well/well" adsorbable MPs such as carbamazepine and diclofenac even when the equilibrium of DOC had already been reached. No strong statistical significance of EBCT and DOC 0 on MP-BV20% could be found due to lack of data and the high heterogeneity of the studies using GAC of different qualities. In further studies, adsorbers should be operated ≫20,000 BV for exact calculation of breakthrough curves, and the following parameters should be recorded: selected MPs; DOC 0; UVA 254 ; EBCT; product name, manufacturing method and raw material of GAC; suspended solids (TSS); backwash interval; backwash program and pressure drop within adsorber. Based on our investigations we generally recommend using reactivated GAC to reduce the environmental impact and to carry out tests on pilot scale to collect reliable data for process design. Copyright © 2017 Elsevier Ltd. All rights reserved.

Technical efficiency of public district hospitals and health centres in Ghana: a pilot study

PubMed Central

Osei, Daniel; d'Almeida, Selassi; George, Melvill O; Kirigia, Joses M; Mensah, Ayayi Omar; Kainyu, Lenity H

2005-01-01

Background The Government of Ghana has been implementing various health sector reforms (e.g. user fees in public health facilities, decentralization, sector-wide approaches to donor coordination) in a bid to improve efficiency in health care. However, to date, except for the pilot study reported in this paper, no attempt has been made to make an estimate of the efficiency of hospitals and/or health centres in Ghana. The objectives of this study, based on data collected in 2000, were: (i) to estimate the relative technical efficiency (TE) and scale efficiency (SE) of a sample of public hospitals and health centres in Ghana; and (ii) to demonstrate policy implications for health sector policy-makers. Methods The Data Envelopment Analysis (DEA) approach was used to estimate the efficiency of 17 district hospitals and 17 health centres. This was an exploratory study. Results Eight (47%) hospitals were technically inefficient, with an average TE score of 61% and a standard deviation (STD) of 12%. Ten (59%) hospitals were scale inefficient, manifesting an average SE of 81% (STD = 25%). Out of the 17 health centres, 3 (18%) were technically inefficient, with a mean TE score of 49% (STD = 27%). Eight health centres (47%) were scale inefficient, with an average SE score of 84% (STD = 16%). Conclusion This pilot study demonstrated to policy-makers the versatility of DEA in measuring inefficiencies among individual facilities and inputs. There is a need for the Planning and Budgeting Unit of the Ghana Health Services to continually monitor the productivity growth, allocative efficiency and technical efficiency of all its health facilities (hospitals and health centres) in the course of the implementation of health sector reforms. PMID:16188021

Preliminary investigation of the STBBI Stigma Scale: Description and pilot results.

PubMed

Wagner, Anne C; MacLean, Rachel

2017-11-09

Sexually transmitted and blood-borne infections (STBBIs) are associated with stigmatizing attitudes and beliefs, which can affect the quality of and access to health care, as well as mental health and quality of life. The current study describes the adaptation from an HIV-related stigma scale and pilot testing of a new STBBI Stigma Scale, assessing the stigmatizing attitudes and beliefs of health and social service providers in Canada. 144 health and social service providers from across Canada completed the newly adapted scale assessing stigma associated with HIV, hepatitis C, other viral STBBIs and bacterial STBBIs, as well as demographic information, a scale of social desirability and measures of convergent and divergent validity. Participants were recruited through listservs and completed the scale online. The new scale, consisting of 21 items for each category, demonstrated excellent internal consistency, reliability, and convergent and divergent validity. The factor structure of the scale supports a tripartite model of stigma consisting of stereotyping, prejudice and discrimination. Stereotyping had the highest relative scores on the subscales, and attitudes regarding other viral STBBIs differed significantly from the other STBBI categories. The new scale provides a contextually relevant and applicable psychometrically valid tool to assess STBBI-related stigma among health and social service providers in Canada. The tool can be used to assess attitudes and beliefs, as well as guide self-assessment and possible trainings for providers.

Demonstration-scale evaluation of a novel high-solids anaerobic digestion process for converting organic wastes to fuel gas and compost.

PubMed

Rivard, C J; Duff, B W; Dickow, J H; Wiles, C C; Nagle, N J; Gaddy, J L; Clausen, E C

1998-01-01

Early evaluations of the bioconversion potential for combined wastes such as tuna sludge and sorted municipal solid waste (MSW) were conducted at laboratory scale and compared conventional low-solids, stirred-tank anaerobic systems with the novel, high-solids anaerobic digester (HSAD) design. Enhanced feedstock conversion rates and yields were determined for the HSAD system. In addition, the HSAD system demonstrated superior resiliency to process failure. Utilizing relatively dry feedstocks, the HSAD system is approximately one-tenth the size of conventional low-solids systems. In addition, the HSAD system is capable of organic loading rates (OLRs) on the order of 20-25 g volatile solids per liter digester volume per d (gVS/L/d), roughly 4-5 times those of conventional systems. Current efforts involve developing a demonstration-scale (pilot-scale) HSAD system. A two-ton/d plant has been constructed in Stanton, CA and is currently in the commissioning/startup phase. The purposes of the project are to verify laboratory- and intermediate-scale process performance; test the performance of large-scale prototype mechanical systems; demonstrate the long-term reliability of the process; and generate the process and economic data required for the design, financing, and construction of full-scale commercial systems. This study presents conformational fermentation data obtained at intermediate-scale and a snapshot of the pilot-scale project.

The Development and Psychometric Properties of the Immigration Law Concerns Scale (ILCS) for HIV Testing.

PubMed

Lechuga, Julia; Galletly, Carol L; Broaddus, Michelle R; Dickson-Gomez, Julia B; Glasman, Laura R; McAuliffe, Timothy L; Vega, Miriam Y; LeGrand, Sarah; Mena, Carla A; Barlow, Morgan L; Valera, Erik; Montenegro, Judith I

2017-11-08

To develop, pilot test, and conduct psychometric analyses of an innovative scale measuring the influence of perceived immigration laws on Latino migrants' HIV-testing behavior. The Immigration Law Concerns Scale (ILCS) was developed in three phases: Phase 1 involved a review of law and literature, generation of scale items, consultation with project advisors, and subsequent revision of the scale. Phase 2 involved systematic translation- back translation and consensus-based editorial processes conducted by members of a bilingual and multi-national study team. In Phase 3, 339 sexually active, HIV-negative Spanish-speaking, non-citizen Latino migrant adults (both documented and undocumented) completed the scale via audio computer-assisted self-interview. The psychometric properties of the scale were tested with exploratory factor analysis and estimates of reliability coefficients were generated. Bivariate correlations were conducted to test the discriminant and predictive validity of identified factors. Exploratory factor analysis revealed a three-factor, 17-item scale. subscale reliability ranged from 0.72 to 0.79. There were significant associations between the ILCS and the HIV-testing behaviors of participants. Results of the pilot test and psychometric analysis of the ILCS are promising. The scale is reliable and significantly associated with the HIV-testing behaviors of participants. Subscales related to unwanted government attention and concerns about meeting moral character requirements should be refined.

A Pilot SMART for Developing an Adaptive Treatment Strategy for Adolescent Depression

PubMed Central

Gunlicks-Stoessel, Meredith; Mufson, Laura; Westervelt, Ana; Almirall, Daniel; Murphy, Susan

2015-01-01

Objective(s) This pilot study was conducted to assess the feasibility and acceptability of four adaptive treatment strategies (ATSs) for adolescent depression to plan for a subsequent full-scale clinical trial. The ATSs aim to address two questions that arise when personalizing treatment: (1) for adolescents treated with Interpersonal Psychotherapy for depressed adolescents (IPT-A) (Mufson et al, 2004), at what time point should therapists make the determination that the adolescent is not likely to respond if the initial treatment plan is continued (week 4 or week 8), and (2) for adolescents who are judged to need their treatment augmented, should the therapist increase the number of IPT-A sessions or add pharmacotherapy (fluoxetine). Method A 16 week pilot sequential multiple assignment randomized trial (SMART) was conducted with 32 adolescents (mean age = 14.9) who had a diagnosis of Major Depressive Disorder, Dysthymic Disorder, or Depressive Disorder NOS. Adolescents were primarily female (75%) and Caucasian (84.4%). Data regarding the feasibility and acceptability of the study and treatment procedures and treatment response rates was collected. Results Week 4 was the more feasible and acceptable decision point for assessing need for a change to treatment. Adolescents, parents, and therapists reported a range of attitudes about medication and more intensive therapy as treatment options. Conclusions The ATSs including the week 4 decision point showed promise in terms of their feasibility and acceptability. Results from the pilot study have yielded additional research questions for the full-scale SMART and will improve our ability to successfully conduct the trial. PMID:25785788

Sleep on Long Haul Layovers and Pilot Fatigue at the Start of the Next Duty Period.

PubMed

Cosgrave, Jan; Wu, Lora J; van den Berg, Margo; Signal, T Leigh; Gander, Philippa H

2018-01-01

Layovers are critical for pilot recovery between flights and minimum layover durations are required by regulation. However, research on the factors affecting layover sleep and safety performance indicators (SPIs) before subsequent flights is relatively sparse. The present project combined data from 6 studies, including 8 long-range and 5 ultra-long range out-and-back trips across a range of different layover destinations (299 pilots in 4-person crews, 410 layovers, 1-3 d layover duration). Sleep was monitored via actigraphy from 3 d pre-trip to at least 3 d post-trip. Pilots rated their sleepiness (Karolinska Sleepiness Scale, KSS) and fatigue (Samn-Perelli scale, SP) at duty start for the inbound flight. Mixed model ANOVAs identified independent associations between fatigue and sleepiness SPIs and operational factors (domicile time of duty start for the inbound flight in six 4-h bins, layover duration, and total sleep time (TST) in the 24 h prior to inbound duty start). TST was greatest on layovers ending between 1200-1559 domicile time (time in the city from which the outbound flight departed) and TST was a significant predictor of both KSS and SP ratings at duty start for the inbound flight. TST in the 24 h prior to the inbound flight was greatest when duty start time allowed for the inclusion of a full domicile night time period. In this dataset, circadian end-time of layovers is a key determinant of pilot fatigue status at the beginning of the inbound duty period.Cosgrove J, Wu LJ, van den Berg M, Signal TL, Gander PH. Sleep on long haul layovers and pilot fatigue at the start of the next duty period. Aerosp Med Hum Perform. 2018; 89(1):19-25.

Transport pilot workload - A comparison of two subjective techniques

NASA Technical Reports Server (NTRS)

Battiste, Vernol; Bortolussi, Michael

1988-01-01

Although SWAT and NASA-TLX workload scales have been compared on numerous occasions, they have not been compared in the context of transport operations. Transport pilot workload has traditionally been classified as long periods of low workload with occasional spikes of high workload. Thus, the relative sensitivity of the scales to variations in workload at the low end of the scale were evaluated. This study was a part of a larger study which investigated workload measures for aircraft certification, conducted in a Phase II certified Link/Boeing 727 simulator. No significant main effects were found for any performance-based measures of workload. However, both SWAT and NASA-TLX were sensitive to differences between high and low workload flights and to differences among flight segments. NASA-TLX (but not SWAT) was sensitive to the increase in workload during the cruise segment of the high workload flight. Between-subject variability was high for SWAT. NASA-TLX was found to be stable when compared in the test/retest paradigm. A test/retest by segment interaction suggested that this was not the case for SWAT ratings.

Bruxism in military pilots and non-pilots: tooth wear and psychological stress.

PubMed

Lurie, Orit; Zadik, Yehuda; Einy, Shmuel; Tarrasch, Ricardo; Raviv, Gil; Goldstein, Liav

2007-02-01

Bruxism is the diurnal or nocturnal para-functional habit of clenching or grinding the teeth and affects 5-10% of the general western population. Bruxism can cause pain and irreversible damage to the teeth, periodontium, masticatory muscles, and temporo-mandibular joint. Variables such as general stress, work-related stress, and personality traits have been increasingly considered as initiating, predisposing, and perpetuating factors for bruxism. We sought to evaluate the potential of work-related stress and personality factors to induce bruxism among military pilots and non-pilot officers. Subjects were 57 healthy male Israel Air Force officers (mean age 25.8+/-4.3 yr). Of these, 17 were jet-pilots, 18 helicopter-pilots, and 22 non-pilot officers. Tooth-wear was classified according to a six-point scale. In addition, the subjects responded to a battery of psychological questionnaires for self-assessment of stress at the workplace and their coping behavior. Bruxism of clinical importance (i.e., with dentin exposure) was found in 69% of the aircrew members but only 27% of the non-pilot group. No difference was found between groups regarding stress levels. Military aircrews may be relatively vulnerable to deleterious bruxism as well as other signs of chronic stress. Among bruxers, pilots tended to show coping strategies that were significantly more emotional and less task-oriented than non-pilots, whereas non-bruxers showed no significant differences in coping behavior. This study suggest that integrating dental and psychological preventive intervention may be helpful.

Subjective evaluation with FAA criteria: A multidimensional scaling approach. [ground track control management

NASA Technical Reports Server (NTRS)

Kreifeldt, J. G.; Parkin, L.; Wempe, T. E.; Huff, E. F.

1975-01-01

Perceived orderliness in the ground tracks of five A/C during their simulated flights was studied. Dynamically developing ground tracks for five A/C from 21 separate runs were reproduced from computer storage and displayed on CRTS to professional pilots and controllers for their evaluations and preferences under several criteria. The ground tracks were developed in 20 seconds as opposed to the 5 minutes of simulated flight using speedup techniques for display. Metric and nonmetric multidimensional scaling techniques are being used to analyze the subjective responses in an effort to: (1) determine the meaningfulness of basing decisions on such complex subjective criteria; (2) compare pilot/controller perceptual spaces; (3) determine the dimensionality of the subjects' perceptual spaces; and thereby (4) determine objective measures suitable for comparing alternative traffic management simulations.

Brief report: Bereaved parents informing research design: The place of a pilot study.

PubMed

Donovan, L A; Wakefield, C E; Russell, V; Hetherington, Kate; Cohn, R J

2018-02-23

Risk minimization in research with bereaved parents is important. However, little is known about which research methods balance the sensitivity required for bereaved research participants and the need for generalizable results. To explore parental experiences of participating in mixed method bereavement research via a pilot study. A convergent parallel mixed method design assessing bereaved parents' experience of research participation. Eleven parents whose child was treated for cancer at The Royal Children's Hospital, Brisbane completed the questionnaire/interview being piloted (n = 8 mothers; n = 3 fathers; >6 months and <6 years bereaved). Of these, eight parents completed the pilot study evaluation questionnaire, providing feedback on their experience of participation. Participants acknowledged the importance of bereaved parents being central to research design and the development of bereavement programs. Sixty-three per cent (n = 5/8) of parents described completion of the questionnaire as 'not at all/a little bit' of a burden. Seventy-five per cent (n = 6/8) of parents opting into the telephone interview described participation as 'not at all/a little bit' of a burden. When considering the latest timeframes for participation in bereavement research 63% (n = 5/8) of parents indicated 'no endpoint.' Findings from the pilot study enabled important adjustments to be made to a large-scale future study. As a research method, pilot studies may be utilized to minimize harm and maximize the potential benefits for vulnerable research participants. A mixed method approach allows researchers to generalize findings to a broader population while also drawing on the depth of the lived experience.

Engineering aspects of ferrate in water and wastewater treatment - a review.

PubMed

Yates, Brian J; Zboril, Radek; Sharma, Virender K

2014-01-01

There is renewed interest in the tetra-oxy compound of +6 oxidation states of iron, ferrate(VI) (Fe(VI)O4(2-)), commonly called ferrate. Ferrate has the potential in cleaner ("greener") technologies for water treatment and remediation processes, as it produces potentially less toxic byproducts than other treatment chemicals (e.g., chlorine). Ferrate has strong potential to oxidize a number of contaminants, including sulfur- and nitrogen-containing compounds, estrogens, and antibiotics. This oxidation capability of ferrate combines with its efficient disinfection and coagulation properties as a multi-purpose treatment chemical in a single dose. This review focuses on the engineering aspects of ferrate use at the pilot scale to remove contaminants in and enhance physical treatment of water and wastewater. In most of the pilot-scale studies, in-line and on-line electrochemical ferrate syntheses have been applied. In this ferrate synthesis, ferrate was directly prepared in solution from an iron anode, followed by direct addition to the contaminant stream. Some older studies applied ferrate as a solid. This review presents examples of removing a range of contaminants by adding ferrate solution to the stream. Results showed that ferrate alone and in combination with additional coagulants can reduce total suspended solids (TSS), chemical oxygen demand (COD), biological oxygen demand (BOD), and organic matter. Ferrate also oxidizes cyanide, sulfide, arsenic, phenols, anilines, and dyes and disinfects a variety of viruses and bacteria. Limitations and drawbacks of the application of ferrate in treating contaminated water on the pilot scale are also presented.

Efficacy and safety of combined treatment of miniscalpel acupuncture and non-steroidal anti-inflammatory drugs: an assessor-blinded randomized controlled pilot study.

PubMed

Jun, Seungah; Lee, Jung Hee; Gong, Han Mi; Chung, Yeon-Joong; Kim, Ju-Ran; Park, Chung A; Choi, Seong Hun; Lee, Geon-Mok; Lee, Hyun-Jong; Kim, Jae Soo

2018-01-12

Chronic neck pain is a common musculoskeletal disease during the lifespan of an individual. With an increase in dependence on computer technology, the prevalence of chronic neck pain is expected to rise and this can lead to socioeconomic problems. We have designed the current pilot study to evaluate the efficacy and safety of miniscalpel acupuncture treatment combined with non-steroidal anti-inflammatory drugs (NSAIDs) in patients with chronic neck pain. This seven-week clinical trial has been designed as an assessor-blinded, randomized controlled trial with three parallel arms. Thirty-six patients will be recruited and randomly allocated to three treatment groups: miniscalpel acupuncture treatment; NSAIDs; and miniscalpel acupuncture treatment combined with NSAIDs. Patients in the miniscalpel acupuncture and combined treatment groups will receive three sessions of miniscalpel acupuncture over a three-week period. Patients in the NSAIDs and combined treatment groups will receive zaltoprofen (one oral tablet, three times a day for three weeks). Primary and secondary outcomes will be measured at weeks 0 (baseline), 1, 2, 3 (primary end point), and 7 (four weeks after treatment completion) using the visual analogue scale and the Neck Disability Index, EuroQol 5-dimension questionnaire, and Patients' Global Impression of Change scale, respectively. Adverse events will also be recorded. This pilot study will provide a basic foundation for a future large-scale trial as well as information about the feasibility of miniscalpel acupuncture treatment combined with NSAIDs for chronic neck pain. Korean Clinical Research Information Service registry, KCT0002258 . Registered on 9 March 2017.

Development of a Social Skills Assessment Screening Scale for Psychiatric Rehabilitation Settings: A Pilot Study

PubMed Central

Bhola, Poornima; Basavarajappa, Chethan; Guruprasad, Deepti; Hegde, Gayatri; Khanam, Fatema; Thirthalli, Jagadisha; Chaturvedi, Santosh K.

2016-01-01

Context: Deficits in social skills may present in a range of psychiatric disorders, particularly in the more serious and persistent conditions, and have an influence on functioning across various domains. Aims: This pilot study aimed at developing a brief measure, for structured evaluation and screening for social skills deficits, which can be easily integrated into routine clinical practice. Settings and Design: The sample consisted of 380 inpatients and their accompanying caregivers, referred to Psychiatric Rehabilitation Services at a tertiary care government psychiatric hospital. Materials and Methods: The evaluation included an Inpatient intake Proforma and the 20-item Social Skills Assessment Screening Scale (SSASS). Disability was assessed using the Indian Disability Evaluation and Assessment Scale (IDEAS) for a subset of 94 inpatients. Statistical Analysis Used: The analysis included means and standard deviations, frequency and percentages, Cronbach's alpha to assess internal consistency, t-tests to assess differences in social skills deficits between select subgroups, and correlation between SSASS and IDEAS scores. Results: The results indicated the profile of social skills deficits assessed among the inpatients with varied psychiatric diagnoses. The “psychosis” group exhibited significantly higher deficits than the “mood disorder” group. Results indicated high internal consistency of the SSASS and adequate criterion validity demonstrated by correlations with select IDEAS domains. Modifications were made to the SSASS following the pilot study. Conclusions: The SSASS has potential value as a measure for screening and individualised intervention plans for social skills training in mental health and rehabilitation settings. The implications for future work on the psychometric properties and clinical applications are discussed. PMID:27833220

Reclamation of grey water for non-potable purposes using pilot-scale solar photocatalytic tubular reactors.

PubMed

Saran, Sarangapany; Arunkumar, Patchaiyappan; Manjari, Gangarapu; Devipriya, Suja P

2018-05-05

Application of pilot-scale slurry-type tubular photocatalytic reactor was tested for the decentralized treatment of actual grey water. The reactors were fabricated by reusing the locally available materials at low cost, operated in batch recycle mode with 25 L of grey water. The influence of operational parameters such as catalysts' concentration, initial slurry pH and addition of H 2 O 2 on COD abatement were optimized. The results show that Ag-decorated TiO 2 showed a two-fold increase in COD abatement than did pure TiO 2 . Better COD abatement was observed under acidic conditions, and addition of H 2 O 2 significantly increases the rate of COD abatement. Within 2 h, 99% COD abatement was observed when the reactor was operated with optimum operational conditions. Silver ion lixiviate was also monitored during the experiment and is five times less than the permissible limits. The catalyst shows good stability even after five cycles without much loss in its photocatalytic activity. The results clearly reveal that pilot-scale slurry tubular solar photocatalytic reactors could be used as a cost-effective method to treat grey water and the resulting clean water could be reused for various non-potable purposes, thus conserving precious water resource. This study favours decentralized grey water treatment and possible scaling up of solar photocatalytic reactor using locally available materials for the potential reuse of treated water.

Effects of operation parameters on nutrient removal from wastewater and high-protein biomass production in a duckweed-based (Lemma aequinoctialis) pilot-scale system.

PubMed

Zhao, Yonggui; Fang, Yang; Jin, Yanling; Huang, Jun; Bao, Shu; He, Zhiming; Wang, Feng; Zhao, Hai

2014-01-01

The effects of water depth, coverage rate and harvest regime on nutrient removal from wastewater and high-protein biomass production were assessed in a duckweed-based (Lemna aequinoctialis) pilot-scale wastewater treatment system (10 basins × 12 m(2)) that is located near Dianchi Lake in China. The results indicated that a water depth of 50 cm, a coverage rate of 150% and a harvest regime of 4 days were preferable conditions, under which excellent records of high-protein duckweed (dry matter production of 6.65 g/m(2)/d with crude protein content of 36.16% and phosphorus content of 1.46%) were obtained at a temperature of 12-21 °C. At the same time, the system achieved a removal efficiency of 66.16, 23.1, 48.3 and 76.52% for NH4(+)-N, TN, TP and turbidity, respectively, with the considerable removal rate of 0.465 g/m(2)/d for TN and 0.134 g/m(2)/d for TP at a hydraulic retention time of 6 days. In additionally, it was found that a lower duckweed density could lead to higher dissolved oxygen in the water and then a higher removal percentage of NH4(+)-N by nitrobacteria. This study obtains the preferable operation conditions for wastewater treatment and high-protein biomass production in a duckweed-based pilot-scale system, supplying an important reference for further large-scale applications of duckweed.

Comparative Study of Green Sub- and Supercritical Processes to Obtain Carnosic Acid and Carnosol-Enriched Rosemary Extracts with in Vitro Anti-Proliferative Activity on Colon Cancer Cells

PubMed Central

Sánchez-Camargo, Andrea del Pilar; García-Cañas, Virginia; Herrero, Miguel; Cifuentes, Alejandro; Ibáñez, Elena

2016-01-01

In the present work, four green processes have been compared to evaluate their potential to obtain rosemary extracts with in vitro anti-proliferative activity against two colon cancer cell lines (HT-29 and HCT116). The processes, carried out under optimal conditions, were: (1) pressurized liquid extraction (PLE, using an hydroalcoholic mixture as solvent) at lab-scale; (2) Single-step supercritical fluid extraction (SFE) at pilot scale; (3) Intensified two-step sequential SFE at pilot scale; (4) Integrated PLE plus supercritical antisolvent fractionation (SAF) at pilot scale. Although higher extraction yields were achieved by using PLE (38.46% dry weight), this extract provided the lowest anti-proliferative activity with no observed cytotoxic effects at the assayed concentrations. On the other hand, extracts obtained using the PLE + SAF process provided the most active rosemary extracts against both colon cancer cell lines, with LC50 ranging from 11.2 to 12.4 µg/mL and from 21.8 to 31.9 µg/mL for HCT116 and HT-29, respectively. In general, active rosemary extracts were characterized by containing carnosic acid (CA) and carnosol (CS) at concentrations above 263.7 and 33.9 mg/g extract, respectively. Some distinct compounds have been identified in the SAF extracts (rosmaridiphenol and safficinolide), suggesting their possible role as additional contributors to the observed strong anti-proliferative activity of CA and CS in SAF extracts. PMID:27941607

Comparative Study of Green Sub- and Supercritical Processes to Obtain Carnosic Acid and Carnosol-Enriched Rosemary Extracts with in Vitro Anti-Proliferative Activity on Colon Cancer Cells.

PubMed

Sánchez-Camargo, Andrea Del Pilar; García-Cañas, Virginia; Herrero, Miguel; Cifuentes, Alejandro; Ibáñez, Elena

2016-12-07

In the present work, four green processes have been compared to evaluate their potential to obtain rosemary extracts with in vitro anti-proliferative activity against two colon cancer cell lines (HT-29 and HCT116). The processes, carried out under optimal conditions, were: (1) pressurized liquid extraction (PLE, using an hydroalcoholic mixture as solvent) at lab-scale; (2) Single-step supercritical fluid extraction (SFE) at pilot scale; (3) Intensified two-step sequential SFE at pilot scale; (4) Integrated PLE plus supercritical antisolvent fractionation (SAF) at pilot scale. Although higher extraction yields were achieved by using PLE (38.46% dry weight), this extract provided the lowest anti-proliferative activity with no observed cytotoxic effects at the assayed concentrations. On the other hand, extracts obtained using the PLE + SAF process provided the most active rosemary extracts against both colon cancer cell lines, with LC 50 ranging from 11.2 to 12.4 µg/mL and from 21.8 to 31.9 µg/mL for HCT116 and HT-29, respectively. In general, active rosemary extracts were characterized by containing carnosic acid (CA) and carnosol (CS) at concentrations above 263.7 and 33.9 mg/g extract, respectively. Some distinct compounds have been identified in the SAF extracts (rosmaridiphenol and safficinolide), suggesting their possible role as additional contributors to the observed strong anti-proliferative activity of CA and CS in SAF extracts.

Exploratory piloted simulator study of the effects of winglets on handling qualities of a representative agricultural airplane

NASA Technical Reports Server (NTRS)

Ogburn, M. E.; Brown, P. W.

1980-01-01

The effects on handling qualities of adding winglets to a representative agricultural aircraft configuration during swath-run maneuvering were evaluated. Aerodynamic data used in the simulation were based on low-speed wind tunnel tests of a full scale airplane and a subscale model. The Cooper-Harper handling qualities rating scale, supplementary pilot comments, and pilot vehicle performance data were used to describe the handling qualities of the airplane with the different wing-tip configurations. Results showed that the lateral-directional handling qualities of the airplane were greatly affected by the application of winglets and winglet cant angle. The airplane with winglets canted out 20 deg exhibited severely degraded lateral directional handling qualities in comparison to the basic airplane. When the winglets were canted inward 10 deg, the flying qualities of the configuration were markedly improved over those of the winglet-canted-out configuration or the basic configuration without winglets, indicating that proper tailoring of the winglet design may afford a potential benefit in the area of handling qualities.

A Low Cost Environmentally Benign Waste Lubricants Recycling/Re-refining Technology.

DTIC Science & Technology

1999-05-01

EXPERIMENTAL 3 2.1 Ceramic Membrane Ultrafiltration Pilot Unit 3 2.2 Polishing/Finishing Pilot Unit 3 2.3 Feed Samples 3 2.4 Sample...development of an additional 2 to 3 sites in the US. 2. EXPERIMENTAL 2.1. Ceramic Membrane Ultrafiltration Pilot Unit A photograph of the pilot...scale ceramic membrane system used in this work is shown in Figure la. Samples of spent turbine oil were charged to the feed tank and heated to 150°C

Age, gender, neck circumference, and Epworth sleepiness scale do not predict obstructive sleep apnea (OSA) in moderate to severe chronic obstructive pulmonary disease (COPD): The challenge to predict OSA in advanced COPD.

PubMed

Soler, Xavier; Liao, Shu-Yi; Marin, Jose Maria; Lorenzi-Filho, Geraldo; Jen, Rachel; DeYoung, Pamela; Owens, Robert L; Ries, Andrew L; Malhotra, Atul

2017-01-01

The combination of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) is associated with substantial morbidity and mortality. We hypothesized that predictors of OSA among patients with COPD may be distinct from OSA in the general population. Therefore, we investigated associations between traditional OSA risk factors (e.g. age), and sleep questionnaires [e.g. Epworth Sleepiness Scale] in 44 patients with advanced COPD. As a second aim we proposed a pilot, simplified screening test for OSA in patients with COPD. In a prospective, observational study of patients enrolled in the UCSD Pulmonary Rehabilitation Program we collected baseline characteristics, cardiovascular events (e.g. atrial fibrillation), and sleep questionnaires [e.g. Pittsburgh Sleep Quality Index (PSQI)]. For the pilot questionnaire, a BMI ≥25 kg/m2 and the presence of cardiovascular disease were used to construct the pilot screening test. Male: 59%; OSA 66%. FEV1 (mean ± SD) = 41.0±18.2% pred., FEV1/FVC = 41.5±12.7%]. Male gender, older age, and large neck circumference were not associated with OSA. Also, Epworth Sleepiness Scale and the STOP-Bang questionnaire were not associated with OSA in univariate logistic regression. In contrast, BMI ≥25 kg/m2 (OR = 3.94, p = 0.04) and diagnosis of cardiovascular disease (OR = 5.06, p = 0.03) were significantly associated with OSA [area under curve (AUC) = 0.74]. The pilot COPD-OSA test (OR = 5.28, p = 0.05) and STOP-Bang questionnaire (OR = 5.13, p = 0.03) were both associated with OSA in Receiver Operating Characteristics (ROC) analysis. The COPD-OSA test had the best AUC (0.74), sensitivity (92%), and specificity (83%). A ten-fold cross-validation validated our results. We found that traditional OSA predictors (e.g. gender, Epworth score) did not perform well in patients with more advanced COPD. Our pilot test may be an easy to implement instrument to screen for OSA. However, a larger validation study is necessary before further clinical implementation is warranted.

Age, gender, neck circumference, and Epworth sleepiness scale do not predict obstructive sleep apnea (OSA) in moderate to severe chronic obstructive pulmonary disease (COPD): The challenge to predict OSA in advanced COPD

PubMed Central

Marin, Jose Maria; Lorenzi-Filho, Geraldo; Jen, Rachel; DeYoung, Pamela; Owens, Robert L.; Ries, Andrew L.; Malhotra, Atul

2017-01-01

The combination of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) is associated with substantial morbidity and mortality. We hypothesized that predictors of OSA among patients with COPD may be distinct from OSA in the general population. Therefore, we investigated associations between traditional OSA risk factors (e.g. age), and sleep questionnaires [e.g. Epworth Sleepiness Scale] in 44 patients with advanced COPD. As a second aim we proposed a pilot, simplified screening test for OSA in patients with COPD. In a prospective, observational study of patients enrolled in the UCSD Pulmonary Rehabilitation Program we collected baseline characteristics, cardiovascular events (e.g. atrial fibrillation), and sleep questionnaires [e.g. Pittsburgh Sleep Quality Index (PSQI)]. For the pilot questionnaire, a BMI ≥25 kg/m2 and the presence of cardiovascular disease were used to construct the pilot screening test. Male: 59%; OSA 66%. FEV1 (mean ± SD) = 41.0±18.2% pred., FEV1/FVC = 41.5±12.7%]. Male gender, older age, and large neck circumference were not associated with OSA. Also, Epworth Sleepiness Scale and the STOP-Bang questionnaire were not associated with OSA in univariate logistic regression. In contrast, BMI ≥25 kg/m2 (OR = 3.94, p = 0.04) and diagnosis of cardiovascular disease (OR = 5.06, p = 0.03) were significantly associated with OSA [area under curve (AUC) = 0.74]. The pilot COPD-OSA test (OR = 5.28, p = 0.05) and STOP-Bang questionnaire (OR = 5.13, p = 0.03) were both associated with OSA in Receiver Operating Characteristics (ROC) analysis. The COPD-OSA test had the best AUC (0.74), sensitivity (92%), and specificity (83%). A ten-fold cross-validation validated our results. We found that traditional OSA predictors (e.g. gender, Epworth score) did not perform well in patients with more advanced COPD. Our pilot test may be an easy to implement instrument to screen for OSA. However, a larger validation study is necessary before further clinical implementation is warranted. PMID:28510598

EVALUATING ION EXCHANGE FOR REMOVING RADIUM FROM GROUNDWATER

EPA Science Inventory

This article, the second in a series, focuses on the results of bench- and pilot-scale studies of ion exchange processes for radium removal from groundwater in Lemont, Ill. Batch and column studies indicated a very high resin selectivity for radium compared with common cations. E...

Validating Performance Level Descriptors (PLDs) for the AP® Environmental Science Exam

ERIC Educational Resources Information Center

Reshetar, Rosemary; Kaliski, Pamela; Chajewski, Michael; Lionberger, Karen

2012-01-01

This presentation summarizes a pilot study conducted after the May 2011 administration of the AP Environmental Science Exam. The study used analytical methods based on scaled anchoring as input to a Performance Level Descriptor validation process that solicited systematic input from subject matter experts.

REMOVAL OF HEPATITIS A VIRUS AND ROTAVIRUS BY DRINKING WATER TREATMENT

EPA Science Inventory

The paper presents quantitative data from a two year study on the removability of rotavirus SA11 and hepatitis A virus added exogenously to Lake Houston raw water during treatment. Processes studied on laboratory and pilot scale included coagulation, filtration, softening and dis...

Goal Attainment Scaling Manual, RUL #5. Materials Development Center Reprint 18.

ERIC Educational Resources Information Center

White, Buffy; And Others

This manual consists of three parts: (1) an introduction to Goal Attainment Scaling (GAS) as an evaluation tool in rehabilitation, (2) a workbook, and (3) a report of a pilot study of GAS. Chapter 1 discusses GAS as an evaluation procedure and defines it as a way of arranging and expressing time-based treatment cr service goals so that results can…

The ITINERIS Scale on the Rights of Persons with Intellectual Disabilities: Development, Pilot Studies and Application at a Country Level in South America

ERIC Educational Resources Information Center

Aznar, A. S.; Gonzalez Castanon, D.; Olate, G.

2012-01-01

Background: The "ITINERIS scale on the rights of persons with intellectual disabilities" (ISRPID) was developed to measure the extent to which people with intellectual disabilities (ID) exercise their rights. Method: The ISRPID was produced through a virtual Delphi group with 37 professionals and relatives of people with ID from four…

Investigations into Improving Dewaterability at a Bio-P/Anaerobic Digestion Plant.

PubMed

Alm, Rebecca; Sealock, Adam W; Nollet, Yabing; Sprouse, George

2016-11-01

  Metropolitan Council Environmental Services has observed poorer than expected dewatering performance at its Empire Plant. This plant has both anaerobic digestion and enhanced biological phosphorus removal in its treatment train. A research program using pilot-scale anaerobic digesters investigated potential solutions to the plant's poor dewaterability. The dewaterability goal was to increase the cake solids from 12% total solids (TS) to 16% TS or higher. This research investigated 20 different reactor conditions including chemical, feed sludge, and digested sludge treatments. At the pilot scale, unaerated storage of waste activated sludge prior to thickening and addition of ferric chloride to digestion was found to achieve dewatered cake solids of nearly 17% TS with the added benefit of reducing polymer demand. Issues including the amount of chemical required and the resulting volatile solids destruction influence the viability of the process change, so a full-scale pilot and financial analysis is recommended before making permanent process changes.

Evaluation of flow hydrodynamics in a pilot-scale dissolved air flotation tank: a comparison between CFD and experimental measurements.

PubMed

Lakghomi, B; Lawryshyn, Y; Hofmann, R

2015-01-01

Computational fluid dynamics (CFD) models of dissolved air flotation (DAF) have shown formation of stratified flow (back and forth horizontal flow layers at the top of the separation zone) and its impact on improved DAF efficiency. However, there has been a lack of experimental validation of CFD predictions, especially in the presence of solid particles. In this work, for the first time, both two-phase (air-water) and three-phase (air-water-solid particles) CFD models were evaluated at pilot scale using measurements of residence time distribution, bubble layer position and bubble-particle contact efficiency. The pilot-scale results confirmed the accuracy of the CFD model for both two-phase and three-phase flows, but showed that the accuracy of the three-phase CFD model would partly depend on the estimation of bubble-particle attachment efficiency.

The reliability and validity of flight task workload ratings

NASA Technical Reports Server (NTRS)

Childress, M. E.; Hart, S. G.; Bortolussi, M. R.

1982-01-01

Twelve instrument-rated general aviation pilots each flew two scenarios in a motion-base simulator. During each flight, the pilots verbally estimated their workload every three minutes. Following each flight, they again estimated workload for each flight segment and also rated their overall workload, perceived performance, and 13 specific factors on a bipolar scale. The results indicate that time (a priori, inflight, or postflight) of eliciting ratings, period to be covered by the ratings (a specific moment in time or a longer period), type of rating scale, and rating method (verbal, written, or other) may be important variables. Overall workload ratings appear to be predicted by different specific scales depending upon the situation, with activity level the best predictor. Perceived performance seems to bear little relationship to observer-rated performance when pilots rate their overall performance and an observer rates specific behaviors. Perceived workload and performance also seem unrelated.

SODIUM DITHIONITE INJECTIONS USED FOR CHROMIUM REDUCTION: NEWSLETTER

EPA Science Inventory

NEWSLETTER NRMRL-ADA- 02116 Paul*, C.J. "Sodium Dithionite Injections Used for Chromium Reduction." In: Groundwater Currents Newsletter 2002. A field-scale pilot study was conducted in 1999 at the U.S. Coast Guard Support Center in El...

Select Generic Dry-Storage Pilot Plant Design for Safeguards and Security by Design (SSBD) per Used Fuel Campaign

DOE Office of Scientific and Technical Information (OSTI.GOV)

Demuth, Scott Francis; Sprinkle, James K.

As preparation to the year-end deliverable (Provide SSBD Best Practices for Generic Dry-Storage Pilot Scale Plant) for the Work Package (FT-15LA040501–Safeguards and Security by Design for Extended Dry Storage), the initial step was to select a generic dry-storage pilot plant design for SSBD. To be consistent with other DOE-NE Fuel Cycle Research and Development (FCR&D) activities, the Used Fuel Campaign was engaged for the selection of a design for this deliverable. For the work Package FT-15LA040501–“Safeguards and Security by Design for Extended Dry Storage”, SSBD will be initiated for the Generic Dry-Storage Pilot Scale Plant described by the layout ofmore » Reference 2. SSBD will consider aspects of the design that are impacted by domestic material control and accounting (MC&A), domestic security, and international safeguards.« less

Being “SMART” about Adolescent Conduct Problems Prevention: Executing a SMART Pilot Study in a Juvenile Diversion Agency

PubMed Central

August, Gerald J.; Piehler, Timothy F.; Bloomquist, Michael L.

2014-01-01

OBJECTIVE The development of adaptive treatment strategies (ATS) represents the next step in innovating conduct problems prevention programs within a juvenile diversion context. Towards this goal, we present the theoretical rationale, associated methods, and anticipated challenges for a feasibility pilot study in preparation for implementing a full-scale SMART (i.e., sequential, multiple assignment, randomized trial) for conduct problems prevention. The role of a SMART design in constructing ATS is presented. METHOD The SMART feasibility pilot study includes a sample of 100 youth (13–17 years of age) identified by law enforcement as early stage offenders and referred for pre-court juvenile diversion programming. Prior data on the sample population detail a high level of ethnic diversity and approximately equal representations of both genders. Within the SMART, youth and their families are first randomly assigned to one of two different brief-type evidence-based prevention programs, featuring parent-focused behavioral management or youth-focused strengths-building components. Youth who do not respond sufficiently to brief first-stage programming will be randomly assigned a second time to either an extended parent- or youth-focused second-stage programming. Measures of proximal intervention response and measures of potential candidate tailoring variables for developing ATS within this sample are detailed. RESULTS Results of the described pilot study will include information regarding feasibility and acceptability of the SMART design. This information will be used to refine a subsequent full-scale SMART. CONCLUSIONS The use of a SMART to develop ATS for prevention will increase the efficiency and effectiveness of prevention programing for youth with developing conduct problems. PMID:25256135

Pilot-scale studies of soil vapor extraction and bioventing for remediation of a gasoline spill at Cameron Station, Alexandria, Virginia

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harrison, W.; Joss, C.J.; Martino, L.E.

Approximately 10,000 gal of spilled gasoline and unknown amounts Of trichloroethylene and benzene were discovered at the US Army`s Cameron Station facility. Because the base is to be closed and turned over to the city of Alexandria in 1995, the Army sought the most rapid and cost-effective means of spill remediation. At the request of the Baltimore District of the US Army Corps of Engineers, Argonne conducted a pilot-scale study to determine the feasibility of vapor extraction and bioventing for resolving remediation problems and to critique a private firm`s vapor-extraction design. Argonne staff, working with academic and private-sector participants, designedmore » and implemented a new systems approach to sampling, analysis and risk assessment. The US Geological Survey`s AIRFLOW model was adapted for the study to simulate the performance of possible remediation designs. A commercial vapor-extraction machine was used to remove nearly 500 gal of gasoline from Argonne-installed horizontal wells. By incorporating numerous design comments from the Argonne project team, field personnel improved the system`s performance. Argonne staff also determined that bioventing stimulated indigenous bacteria to bioremediate the gasoline spin. The Corps of Engineers will use Argonne`s pilot-study approach to evaluate remediation systems at field operation sites in several states.« less

Effect of Alternate Nostril Breathing Exercise on Experimentally Induced Anxiety in Healthy Volunteers Using the Simulated Public Speaking Model: A Randomized Controlled Pilot Study.

PubMed

Kamath, Ashwin; Urval, Rathnakar P; Shenoy, Ashok K

2017-01-01

A randomized controlled pilot study was carried out to determine the effect of a 15-minute practice of ANB exercise on experimentally induced anxiety using the simulated public speaking model in yoga-naïve healthy young adults. Thirty consenting medical students were equally divided into test and control groups. The test group performed alternate nostril breathing exercise for 15 minutes, while the control group sat in a quiet room before participating in the simulated public speaking test (SPST). Visual Analog Mood Scale and Self-Statements during Public Speaking scale were used to measure the mood state at different phases of the SPST. The psychometric scores of both groups were comparable at baseline. Repeated-measures ANOVA showed a significant effect of phase ( p < 0.05), but group and gender did not have statistically significant influence on the mean anxiety scores. However, the test group showed a trend towards lower mean scores for the anxiety factor when compared with the control group. Considering the limitations of this pilot study and the trend seen towards lower anxiety in the test group, alternate nostril breathing may have potential anxiolytic effect in acute stressful situations. A study with larger sample size is therefore warranted. This trial is registered with CTRI/2014/03/004460.

Effect of Alternate Nostril Breathing Exercise on Experimentally Induced Anxiety in Healthy Volunteers Using the Simulated Public Speaking Model: A Randomized Controlled Pilot Study

PubMed Central

Urval, Rathnakar P.; Shenoy, Ashok K.

2017-01-01

A randomized controlled pilot study was carried out to determine the effect of a 15-minute practice of ANB exercise on experimentally induced anxiety using the simulated public speaking model in yoga-naïve healthy young adults. Thirty consenting medical students were equally divided into test and control groups. The test group performed alternate nostril breathing exercise for 15 minutes, while the control group sat in a quiet room before participating in the simulated public speaking test (SPST). Visual Analog Mood Scale and Self-Statements during Public Speaking scale were used to measure the mood state at different phases of the SPST. The psychometric scores of both groups were comparable at baseline. Repeated-measures ANOVA showed a significant effect of phase (p < 0.05), but group and gender did not have statistically significant influence on the mean anxiety scores. However, the test group showed a trend towards lower mean scores for the anxiety factor when compared with the control group. Considering the limitations of this pilot study and the trend seen towards lower anxiety in the test group, alternate nostril breathing may have potential anxiolytic effect in acute stressful situations. A study with larger sample size is therefore warranted. This trial is registered with CTRI/2014/03/004460. PMID:29159176

[Diagnostic test scale SI5: Assessment of sacroiliac joint dysfunction].

PubMed

Acevedo González, Juan C; Quintero Oliveros, Silvia

2015-01-01

Sacroiliac joint dysfunction is a known cause of low back pain. We think that a diagnostic score scale (SI5) may be performed to assess diagnostic utility of clinical signs of sacroiliac joint dysfunction. The primary aim of the present study was to conduct the pilot study of our new diagnostic score scale, the SI5, for sacroiliac joint syndrome. We reviewed the literature on clinical characteristics, diagnostic tests and imaging most commonly used in diagnosing sacroiliac joint dysfunction. Our group evaluated the diagnostic utility of these aspects and we used those considered most representative to develop the SI5 diagnostic scale. The SI5 scale was applied to 22 patients with low back pain; afterwards, the standard test for diagnosing this pathology (selective blockage of the SI joint) was also performed on these patients. The sensitivity and specificity for each sign were also assessed and the diagnostic scale called SI5 was then proposed, based on these data. The most sensitive clinical tests for diagnosing SI joint dysfunction were 2 patient-reported clinical characteristics, the Laguerre Test, sacroiliac rocking test and Yeomans test (greater than 80% sensitivity). The tests with greatest diagnostic specificity (>80%) were the Lewitt test, Piedallu test and Gillet test. The proposed SI5 test score scale showed sensitivity of 73% and specificity of 71%. Sacroiliac joint syndrome has been shown to produce low back pain frequently; however, the diagnostic value of examination tests for sacroiliac joint pain has been questioned by other authors. The pilot study on the SI5 diagnostic score scale showed good sensitivity and specificity. However, the process of statistical validation of the SI5 needs to be continued. Copyright © 2014 Sociedad Española de Neurocirugía. Published by Elsevier España. All rights reserved.

Opto-acoustic image fusion technology for diagnostic breast imaging in a feasibility study

NASA Astrophysics Data System (ADS)

Zalev, Jason; Clingman, Bryan; Herzog, Don; Miller, Tom; Ulissey, Michael; Stavros, A. T.; Oraevsky, Alexander; Lavin, Philip; Kist, Kenneth; Dornbluth, N. C.; Otto, Pamela

2015-03-01

Functional opto-acoustic (OA) imaging was fused with gray-scale ultrasound acquired using a specialized duplex handheld probe. Feasibility Study findings indicated the potential to more accurately characterize breast masses for cancer than conventional diagnostic ultrasound (CDU). The Feasibility Study included OA imagery of 74 breast masses that were collected using the investigational Imagio® breast imaging system. Superior specificity and equal sensitivity to CDU was demonstrated, suggesting that OA fusion imaging may potentially obviate the need for negative biopsies without missing cancers in a certain percentage of breast masses. Preliminary results from a 100 subject Pilot Study are also discussed. A larger Pivotal Study (n=2,097 subjects) is underway to confirm the Feasibility Study and Pilot Study findings.

[Design and validation of scales to measure adolescent attitude toward eating and toward physical activity].

PubMed

Lima-Serrano, Marta; Lima-Rodríguez, Joaquín Salvador; Sáez-Bueno, Africa

2012-01-01

Different authors suggest that attitude is a mediator in behavior change, so it is a predictor of behavior practice. The main of this study was to design and to validate two scales for measure adolescent attitude toward healthy eating and adolescent attitude toward healthy physical activity. Scales were design based on a literature review. After, they were validated using an on-line Delphi Panel with eighteen experts, a pretest, and a pilot test with a sample of 188 high school students. Comprehensibility, content validity, adequacy, as well as the reliability (alpha of Cronbach test), and construct validity (exploratory factor analysis) of scales were tested. Scales validated by experts were considered appropriate in the pretest. In the pilot test, the ten-item Attitude to Eating Scale obtained α=0.72. The eight-item Attitude to Physical Activity Scale obtained α=0.86. They showed evidence of one-dimensional interpretation after factor analysis, a) all items got weights r>0.30 in first factor before rotations, b) the first factor explained a significant proportion of variance before rotations, and c) the total variance explained by the main factors extracted was greater than 50%. The Scales showed their reliability and validity. They could be employed to assess attitude to these priority intervention areas in Spanish adolescents, and to evaluate this intermediate result of health interventions and health programs.

Removal of Giardia and Cryptosporidium in drinking water treatment: a pilot-scale study.

PubMed

Hsu, Bing Mu; Yeh, Hsuan Hsien

2003-03-01

Giardia and Cryptosporidium have emerged as waterborne pathogens of concern for public health. The aim of this study is to examine both parasites in the water samples taken from three pilot-scale plant processes located in southern Taiwan, to upgrade the current facilities. Three processes include: conventional process without prechlorination (Process 1), conventional process plus ozonation and pellet softening (Process 2), and integrated membrane process (MF plus NF) followed conventional process (Process 3). The detection methods of both parasites are modified from USEPA Methods 1622 and 1623. Results indicated that coagulation, sedimentation and filtration removed the most percentage of both protozoan parasites. The pre-ozonation step can destruct both parasites, especially for Giardia cysts. The microfiltration systems can intercept Giardia cysts and Cryptosporidium oocysts completely. A significant correlation between water turbidity and Cryptosporidium oocysts was found in this study. The similar results were also found between three kinds of particles (phi=3-5,5-8 and 8-10 microm) and Cryptosporidium oocysts.

Scaling up ART adherence clubs in the public sector health system in the Western Cape, South Africa: a study of the institutionalisation of a pilot innovation.

PubMed

MacGregor, Hayley; McKenzie, Andrew; Jacobs, Tanya; Ullauri, Angelica

2018-04-25

In 2011, a decision was made to scale up a pilot innovation involving 'adherence clubs' as a form of differentiated care for HIV positive people in the public sector antiretroviral therapy programme in the Western Cape Province of South Africa. In 2016 we were involved in the qualitative aspect of an evaluation of the adherence club model, the overall objective of which was to assess the health outcomes for patients accessing clubs through epidemiological analysis, and to conduct a health systems analysis to evaluate how the model of care performed at scale. In this paper we adopt a complex adaptive systems lens to analyse planned organisational change through intervention in a state health system. We explore the challenges associated with taking to scale a pilot that began as a relatively simple innovation by a non-governmental organisation. Our analysis reveals how a programme initially representing a simple, unitary system in terms of management and clinical governance had evolved into a complex, differentiated care system. An innovation that was assessed as an excellent idea and received political backing, worked well whilst supported on a small scale. However, as scaling up progressed, challenges have emerged at the same time as support has waned. We identified a 'tipping point' at which the system was more likely to fail, as vulnerabilities magnified and the capacity for adaptation was exceeded. Yet the study also revealed the impressive capacity that a health system can have for catalysing novel approaches. We argue that innovation in largescale, complex programmes in health systems is a continuous process that requires ongoing support and attention to new innovation as challenges emerge. Rapid scaling up is also likely to require recourse to further resources, and a culture of iterative learning to address emerging challenges and mitigate complex system errors. These are necessary steps to the future success of adherence clubs as a cornerstone of differentiated care. Further research is needed to assess the equity and quality outcomes of a differentiated care model and to ensure the inclusive distribution of the benefits to all categories of people living with HIV.

Subjective Measurements of In-Flight Sleep, Circadian Variation, and Their Relationship with Fatigue.

PubMed

van den Berg, Margo J; Wu, Lora J; Gander, Philippa H

This study examined whether subjective measurements of in-flight sleep could be a reliable alternative to actigraphic measurements for monitoring pilot fatigue in a large-scale survey. Pilots (3-pilot crews) completed a 1-page survey on outbound and inbound long-haul flights crossing 1-7 time zones (N = 586 surveys) between 53 city pairs with 1-d layovers. Across each flight, pilots documented flight start and end times, break times, and in-flight sleep duration and quality if they attempted sleep. They also rated their fatigue (Samn-Perelli Crew Status Check) and sleepiness (Karolinska Sleepiness Scale) at top of descent (TOD). Mixed model ANCOVA was used to identify independent factors associated with sleep duration, quality, and TOD measures. Domicile time was used as a surrogate measure of circadian phase. Sleep duration increased by 10.2 min for every 1-h increase in flight duration. Sleep duration and quality varied by break start time, with significantly more sleep obtained during breaks starting between (domicile) 22:00-01:59 and 02:00-05:59 compared to earlier breaks. Pilots were more fatigued and sleepy at TOD on flights arriving between 02:00-05:59 and 06:00-09:59 domicile time compared to other flights. With every 1-h increase in sleep duration, sleepiness ratings at TOD decreased by 0.6 points and fatigue ratings decreased by 0.4 points. The present findings are consistent with previous actigraphic studies, suggesting that self-reported sleep duration is a reliable alternative to actigraphic sleep in this type of study, with use of validated measures, sufficiently large sample sizes, and where fatigue risk is expected to be low. van den Berg MJ, Wu LJ, Gander PH. Subjective measurements of in-flight sleep, circadian variation, and their relationship with fatigue. Aerosp Med Hum Perform. 2016; 87(10):869-875.

A pilot randomized controlled trial comparing prenatal yoga to perinatal health education for antenatal depression.

PubMed

Uebelacker, Lisa A; Battle, Cynthia L; Sutton, Kaeli A; Magee, Susanna R; Miller, Ivan W

2016-06-01

We conducted a pilot randomized controlled trial (RCT) comparing a prenatal yoga intervention to perinatal-focused health education in pregnant women with depression. Findings document acceptability and feasibility of the yoga intervention: no yoga-related injuries were observed, instructors showed fidelity to the yoga manual, and women rated interventions as acceptable. Although improvements in depression were not statistically different between groups, they favored yoga. This study provides support for a larger scale RCT examining prenatal yoga to improve mood during pregnancy.

An open-label pilot study of aripiprazole for male and female veterans with chronic post-traumatic stress disorder who respond suboptimally to antidepressants.

PubMed

Youssef, Nagy A; Marx, Christine E; Bradford, Daniel W; Zinn, Sandra; Hertzberg, Michael A; Kilts, Jason D; Naylor, Jennifer C; Butterfield, Marian I; Strauss, Jennifer L

2012-07-01

Emerging data suggest that second-generation antipsychotics such as aripiprazole may be effective in the treatment of post-traumatic stress disorder (PTSD). However, few clinical trials have used aripiprazole in PTSD, and data are limited on its use in Veterans with PTSD. The objective of this pilot trial was to investigate the safety and efficacy of aripiprazole in Veterans with PTSD. Ten individuals (five men and five women) meeting the Diagnostic and statistical manual of mental disorders, 4th ed., PTSD criteria participated in this 12-week, open-label, flexibly dosed monotherapy trial. The dose range of aripiprazole was 5-30 mg/day, titrated to tolerability and clinical response. The primary outcome measure was the Clinician-Administered PTSD Scale. Additional outcomes included the Short PTSD Rating Interview, the Treatment Outcome PTSD Scale (Top-8), the Davidson Trauma Scale, the Positive and Negative Syndrome Scale, the Beck Depression Inventory-Fast Screen, and Clinical Global Impressions-Improvement. Eight participants completed the study, and aripiprazole was generally well tolerated and associated with a significant improvement in PTSD symptoms, as measured by the Clinician-Administered PTSD Scale (primary outcome measure) and by the Short PTSD Rating Interview, the Treatment Outcome PTSD Scale, and the Davidson Trauma Scale. An improvement was also observed on all three Positive and Negative Syndrome Scale subscales and the Beck Depression Inventory-Fast Screen, and the average Clinical Global Impressions-Improvement ratings indicated that patients were 'much improved'. These promising initial results merit further investigation in a larger, randomized-controlled trial.

Low Income Women and Physician Breastfeeding Advice: A Regional Assessment

ERIC Educational Resources Information Center

Stolzer, J; Zeece, Pauline

2006-01-01

Objectives: The aims of the pilot study presented here were to determine whether low income women were receiving compendious breastfeeding advice from their attending physicians. Design: This study assessed low income women's reports of physician breastfeeding advice using a newly designed Likert scaled survey based on the American Surgeon…

School Nurses' Knowledge of Autism Spectrum Disorders

ERIC Educational Resources Information Center

Strunk, Julie A.

2009-01-01

The purpose of this study was to determine school nurses' working knowledge of autism spectrum disorders (ASDs). The current knowledge of school nurses was investigated by means of a mixed-method exploratory descriptive pilot study. Instrumentation included a scale that measured the knowledge of school nurses in regard to ASD, including medication…

Characterizing The Microbial Community In A TCE DNAPL Site: SABRE Column And Field Studies

EPA Science Inventory

The SABRE (Source Area BioREmediation) project is evaluating accelerated anaerobic bioremediation of chlorinated solvents in areas of high concentration, such as DNAPL source areas. In support of a field scale pilot test, column studies were conducted to design the system and ob...

SCHOOL INTEGRATION CONTROVERSIES IN NEW YORK CITY, A PILOT STUDY.

ERIC Educational Resources Information Center

SWANSON, BERT E.

THE MAJOR PROBLEM OF THIS PREPARATORY RESEARCH PROGRAM WAS TO ASCERTAIN THE FEASIBILITY OF MAKING A FULL-SCALE STUDY OF THE DYNAMICS OF SCHOOL INTEGRATION CONTROVERSIES IN NEW YORK CITY. METHODS INVOLVED INTERVIEWING AND OBSERVING LEADERS AT CITYWIDE AND NEIGHBORHOOD LEVELS, INCLUDING SCHOOL ADMINISTRATORS, SCHOOL BOARD MEMBERS, TEACHERS, PARENT…

WET OXIDATION OF MUNICIPAL SLUDGE BY THE VERTICAL TUBE REACTOR

EPA Science Inventory

A study was undertaken to assess the feasibility of carrying out oxidation of dilute sewage sludge by means of the vertical tube reactor (VTR) system. A pilot scale facility along with a laboratory reactor were used for this study. Dilute sewage sludge was oxidized in the laborat...

SUPERFUND TREATABILITY CLEARINGHOUSE: INPUT/OUTPUT DATA FOR SEVERAL TREATMENT TECHNOLOGIES

EPA Science Inventory

This treatability study is a pilot-scale evaluation of a thin-film evaporator (TFE) for volatile organics (VO) removal from oily sludges such as refinery sludges. TFEs were studied to evaluate their use to remove and recover VO from these sludges prior to land treatment. This w...

HANFORD MEDIUM-LOW CURIE WASTE PRETREATMENT ALTERNATIVES PROJECT FRACTIONAL CRYSTALLIZATION PILOT SCALE TESTING FINAL REPORT

DOE Office of Scientific and Technical Information (OSTI.GOV)

HERTING DL

2008-09-16

The Fractional Crystallization Pilot Plant was designed and constructed to demonstrate that fractional crystallization is a viable way to separate the high-level and low-activity radioactive waste streams from retrieved Hanford single-shell tank saltcake. The focus of this report is to review the design, construction, and testing details of the fractional crystallization pilot plant not previously disseminated.

Development of a Dynamically Scaled Generic Transport Model Testbed for Flight Research Experiments

NASA Technical Reports Server (NTRS)

Jordan, Thomas; Langford, William; Belcastro, Christine; Foster, John; Shah, Gautam; Howland, Gregory; Kidd, Reggie

2004-01-01

This paper details the design and development of the Airborne Subscale Transport Aircraft Research (AirSTAR) test-bed at NASA Langley Research Center (LaRC). The aircraft is a 5.5% dynamically scaled, remotely piloted, twin-turbine, swept wing, Generic Transport Model (GTM) which will be used to provide an experimental flight test capability for research experiments pertaining to dynamics modeling and control beyond the normal flight envelope. The unique design challenges arising from the dimensional, weight, dynamic (inertial), and actuator scaling requirements necessitated by the research community are described along with the specific telemetry and control issues associated with a remotely piloted subscale research aircraft. Development of the necessary operational infrastructure, including operational and safety procedures, test site identification, and research pilots is also discussed. The GTM is a unique vehicle that provides significant research capacity due to its scaling, data gathering, and control characteristics. By combining data from this testbed with full-scale flight and accident data, wind tunnel data, and simulation results, NASA will advance and validate control upset prevention and recovery technologies for transport aircraft, thereby reducing vehicle loss-of-control accidents resulting from adverse and upset conditions.

Research on the enhancement of biological nitrogen removal at low temperatures from ammonium-rich wastewater by the bio-electrocoagulation technology in lab-scale systems, pilot-scale systems and a full-scale industrial wastewater treatment plant.

PubMed

Li, Liang; Qian, Guangsheng; Ye, Linlin; Hu, Xiaomin; Yu, Xin; Lyu, Weijian

2018-09-01

In cold areas, nitrogen removal performance of wastewater treatment plants (WWTP) declines greatly in winter. This paper systematically describes the enhancement effect of a periodic reverse electrocoagulation technology on biological nitrogen removal at low temperatures. The study showed that in the lab-scale systems, the electrocoagulation technology improved the biomass amount, enzyme activity and the amount of nitrogen removal bacteria (Nitrosomonas, Nitrobacter, Paracoccus, Thauera and Enterobacter). This enhanced nitrification and denitrification of activated sludge at low temperatures. In the pilot-scale systems, the electrocoagulation technology increased the relative abundance of cold-adapted microorganisms (Luteimonas and Trueperaceae) at low temperatures. In a full-scale industrial WWTP, comparison of data from winter 2015 and winter 2016 showed that effluent chemical oxygen demand (COD), NH 4 + -N, and NO 3 - -N reduced by 10.37, 3.84, and 136.43 t, respectively, throughout the winter, after installation of electrocoagulation devices. These results suggest that the electrocoagulation technology is able to improve the performance of activated sludge under low-temperature conditions. This technology provides a new way for upgrading of the performance of WWTPs in cold areas. Copyright © 2018 Elsevier Ltd. All rights reserved.

Predicting the performance uncertainty of a 1-MW pilot-scale carbon capture system after hierarchical laboratory-scale calibration and validation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xu, Zhijie; Lai, Canhai; Marcy, Peter William

2017-05-01

A challenging problem in designing pilot-scale carbon capture systems is to predict, with uncertainty, the adsorber performance and capture efficiency under various operating conditions where no direct experimental data exist. Motivated by this challenge, we previously proposed a hierarchical framework in which relevant parameters of physical models were sequentially calibrated from different laboratory-scale carbon capture unit (C2U) experiments. Specifically, three models of increasing complexity were identified based on the fundamental physical and chemical processes of the sorbent-based carbon capture technology. Results from the corresponding laboratory experiments were used to statistically calibrate the physical model parameters while quantifying some of theirmore » inherent uncertainty. The parameter distributions obtained from laboratory-scale C2U calibration runs are used in this study to facilitate prediction at a larger scale where no corresponding experimental results are available. In this paper, we first describe the multiphase reactive flow model for a sorbent-based 1-MW carbon capture system then analyze results from an ensemble of simulations with the upscaled model. The simulation results are used to quantify uncertainty regarding the design’s predicted efficiency in carbon capture. In particular, we determine the minimum gas flow rate necessary to achieve 90% capture efficiency with 95% confidence.« less

DESIGN OF A MTBE REMEDIATION TECHNOLOGY EVALUATION

EPA Science Inventory

This study examines the intrinsic variability of dissolved MTBE concentrations in ground water during the course of a pilot-scale bioremedial technology trial in Port Hueneme, California. A pre-trial natural gradient tracer experiment using bromide was conducted in an anaerobic t...

The Impact of Temperature on Anaerobic Biological Perchlorate Treatment

EPA Science Inventory

A 20-month pilot-scale study was conducted to examine the impact of temperature on the performance of an anaerobic biological contactor used to treat perchlorate-contaminated water. The contactor was successfully acclimated with indigenous micro-organisms. Influent temperatures...

Improvement of workload estimation techniques in piloting tasks

NASA Technical Reports Server (NTRS)

Wierwille, W. W.

1984-01-01

The Modified Cooper-Harper (MCH) scale has been shown to be a sensitive indicator of workload in several different types of aircrew tasks. The MCH scale, which is a 10 point scale, and five newly devised scales were examined in two different aircraft simulator experiments in which pilot loading was treated as an independent variable. The five scales included a 15 point scale, computerized versions of the MCH and 15 point scales, a scale in which the decision tree was removed, and one in which a 15 point left-to-right format was used. The results indicate that while one of the new scales may be more sensitive in a given experiment, task dependency is a problem. The MCH scale on the other hand exhibits consistent sensitivity and remains the scale recommended for general use. The MCH scale results are consistent with earlier experiments also. The results of the rating scale experiments are presented and the questionnaire results which were directed at obtaining a better understanding of the reasons for the relative sensitivity of the MCH scale and its variations are described.

Pilot testing of a membrane system for postcombustion CO 2 capture

DOE Office of Scientific and Technical Information (OSTI.GOV)

Merkel, Tim; Kniep, Jay; Wei, Xiaotong

2015-09-30

This final report summarizes work conducted for the U.S. Department of Energy, National Energy Technology Laboratory (DOE) to scale up an efficient post-combustion CO 2 capture membrane process to the small pilot test stage (award number DE-FE0005795). The primary goal of this research program was to design, fabricate, and operate a membrane CO 2 capture system to treat coal-derived flue gas containing 20 tonnes CO 2/day (20 TPD). Membrane Technology and Research (MTR) conducted this project in collaboration with Babcock and Wilcox (B&W), the Electric Power Research Institute (EPRI), WorleyParsons (WP), the Illinois Sustainable Technology Center (ISTC), Enerkem (EK), andmore » the National Carbon Capture Center (NCCC). In addition to the small pilot design, build and slipstream testing at NCCC, other project efforts included laboratory membrane and module development at MTR, validation field testing on a 1 TPD membrane system at NCCC, boiler modeling and testing at B&W, a techno-economic analysis (TEA) by EPRI/WP, a case study of the membrane technology applied to a ~20 MWe power plant by ISTC, and an industrial CO 2 capture test at an Enerkem waste-to-biofuel facility. The 20 TPD small pilot membrane system built in this project successfully completed over 1,000 hours of operation treating flue gas at NCCC. The Polaris™ membranes used on this system demonstrated stable performance, and when combined with over 10,000 hours of operation at NCCC on a 1 TPD system, the risk associated with uncertainty in the durability of postcombustion capture membranes has been greatly reduced. Moreover, next-generation Polaris membranes with higher performance and lower cost were validation tested on the 1 TPD system. The 20 TPD system also demonstrated successful operation of a new low-pressure-drop sweep module that will reduce parasitic energy losses at full scale by as much as 10 MWe. In modeling and pilot boiler testing, B&W confirmed the viability of CO 2 recycle to the boiler as envisioned in the MTR process design. The impact of this CO 2 recycle on boiler efficiency was quantified and incorporated into a TEA of the membrane capture process applied to a full-scale power plant. As with previous studies, the TEA showed the membrane process to be lower cost than the conventional solvent capture process even at 90% CO 2capture. A sensitivity study indicates that the membrane capture cost decreases significantly if the 90% capture requirement is relaxed. Depending on the process design, a minimum capture cost is achieved at 30-60% capture, values that would meet proposed CO 2 emission regulations for coal-fired power plants. In summary, this project has successfully advanced the MTR membrane capture process through small pilot testing (technology readiness level 6). The technology is ready for future scale-up to the 10 MWe size.« less

Laboratory and Pilot Scale Evaluation of Coagulation, Clarification, and Filtration for Upgrading Sewage Lagoon Effluents.

DTIC Science & Technology

1980-08-01

AD-AGAB 906 ARMY ENGINEER WATERWAYS EXPERIMENT STATION VICKSBURG--ETC FIG 14/2 LABORATORY AND PILOT SCALE EVALUATION OF COAGULATION, CLARIFICA -ETC U...FILTRATION FOR LWGRADING JEWAGE LAGOON EFFLUENTS~ w IL j0 ( M John ullinane, Jr., Richard A. hafer (0 Environmental Laboratory gel U. S. Army Engineer ...Shafer 9. PERFORMING ORGANIZATION NAME AND ADORESS SO. PROGRAM ELEMENT, PROJECT, TASK AREA a WORK UNIT NUMBERS U. S. Army Engineer Waterways Experiment

Pilot scale fermentation of Jerusalem artichoke tuber pulp mashes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ziobro, G.C.; Williams, L.A.

1983-01-01

Processing and fermentation of Jerusalem artichoke (Helianthus tuberosus L.) tuber pulp mashes were successfully carried out at pilot scales of 60 gallons and 1000 gallons. Whole tubers were pulped mechanically into a thick mash and fermented, using commercially available Saccharomyces cerevisiae and selected strains of Kluyveromyces fragilis. EtOH fermentation yields ranging from 50-70% of theoretical maximum were obtained in 3-4 days. Several problems regarding the processing and direct fermentation of tuber pulp mashes are discussed.

Characterization and partitioning of the char ash collected after the processing of pine wood chips in a pilot-scale gasification unit

Treesearch

Thomas L. Eberhardt; Hui Pan; Leslie H. Groom; Chi-Leung So

2011-01-01

Southern yellow pine wood chips were used as the feedstock for a pilot-scale gasification unit coupled with a 25 kW generator. The pulp-grade wood chips were relatively free of bark and low in ash content. Processing this feedstock yielded a black/sooty by-product that upon combustion in a muffle furnace resulted in an ash content of about 48%. The term "char ash...

Pilot-scale gasification of woody biomass

Treesearch

Thomas Elder; Leslie H. Groom

2011-01-01

The gasification of pine and mixed-hardwood chips has been carried out in a pilot-scale system at a range of gas flow rates. Consuming ~17-30 kgh-1 of feedstock, the producer gas was composed of ~200 dm3 m-3 carbon monoxide, 12 dm3 m-3 carbon dioxide, 30 dm3 m-3 methane and 190 dm3 m-3 hydrogen, with an energy content of ~6 MJ m-3 for both feedstocks. It was found that...

Coupled solar photo-Fenton and biological treatment for the degradation of diuron and linuron herbicides at pilot scale.

PubMed

Farré, Maria José; Maldonado, Manuel Ignacio; Gernjak, Wolfgang; Oller, Isabel; Malato, Sixto; Domènech, Xavier; Peral, José

2008-06-01

A coupled solar photo-Fenton (chemical) and biological treatment has been used to remove biorecalcitrant diuron (42 mg l(-1)) and linuron (75 mg l(-1)) herbicides from water at pilot plant scale. The chemical process has been carried out in a 82 l solar pilot plant made up by four compound parabolic collector units, and it was followed by a biological treatment performed in a 40 l sequencing batch reactor. Two Fe(II) doses (2 and 5 mg l(-1)) and sequential additions of H2O2 (20 mg l(-1)) have been used to chemically degrade the initially polluted effluent. Next, biodegradability at different oxidation states has been assessed by means of BOD/COD ratio. A reagent dose of Fe=5 mg l(-1) and H2O2=100 mg l(-1) has been required to obtain a biodegradable effluent after 100 min of irradiation time. Finally, the organic content of the photo-treated solution has been completely assimilated by a biomass consortium in the sequencing batch reactor using a total suspended solids concentration of 0.2 g l(-1) and a hydraulic retention time of 24h. Comparison between the data obtained at pilot plant scale (specially the one corresponding to the chemical step) and previously published data from a similar system performing at laboratory scale, has been carried out.

Demonstration of coal reburning for cyclone boiler NO{sub x} control. Appendix, Book 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

Based on the industry need for a pilot-scale cyclone boiler simulator, Babcock Wilcox (B&W) designed, fabricated, and installed such a facility at its Alliance Research Center (ARC) in 1985. The project involved conversion of an existing pulverized coal-fired facility to be cyclone-firing capable. Additionally, convective section tube banks were installed in the upper furnace in order to simulate a typical boiler convection pass. The small boiler simulator (SBS) is designed to simulate most fireside aspects of full-size utility boilers such as combustion and flue gas emissions characteristics, fireside deposition, etc. Prior to the design of the pilot-scale cyclone boiler simulator,more » the various cyclone boiler types were reviewed in order to identify the inherent cyclone boiler design characteristics which are applicable to the majority of these boilers. The cyclone boiler characteristics that were reviewed include NO{sub x} emissions, furnace exit gas temperature (FEGT) carbon loss, and total furnace residence time. Previous pilot-scale cyclone-fired furnace experience identified the following concerns: (1) Operability of a small cyclone furnace (e.g., continuous slag tapping capability). (2) The optimum cyclone(s) configuration for the pilot-scale unit. (3) Compatibility of NO{sub x} levels, carbon burnout, cyclone ash carryover to the convection pass, cyclone temperature, furnace residence time, and FEGT.« less

Organizational pressures and mitigating strategies in small commercial aviation: findings from Alaska.

PubMed

Bearman, Chris; Paletz, Susannah B F; Orasanu, Judith; Brooks, Benjamin P

2009-12-01

Recent attention has focused on the way in which organizational factors can erode safety in aviation, particularly in regions that have a high accident rate, such as Alaska. The present study builds on this work by examining the direct and indirect pressures that can be exerted on pilots by Alaskan operators. In addition, the paper examines ways in which organizations and individuals manage the effects of pressure. Using the critical incident method to uncover situations where the pilot's skills had been challenged, 28 pilots who flew in Alaska were interviewed. A bottom-up qualitative analysis revealed a range of organizational pressures and mitigating strategies. Pilots in Alaska encountered both implicit and explicit norms and expectations to fly in marginal conditions. Pressure also arose from pilots' awareness of the need for their company to make money and from perceived job competition. Some Alaskan operators were able to mitigate the effects of pressure on their pilots and some pilots reported mitigating pressure to fly by managing their employer's expectations and re-emphasizing safety. Organizational factors were found to be an important source of pressure for pilots and are likely to contribute to the high accident rate in Alaska. Balancing the competing demands of safety and productivity may be extremely difficult for many small operators, which places a heavy reliance on the decision making of individuals. Both the subtle pressures on individual pilots and strategies for mitigating those pressures are, therefore, extremely important to safety and productivity in small-scale commercial aviation.

Rural Latinos' mental wellbeing: a mixed-methods pilot study of family, environment and social isolation factors.

PubMed

Stacciarini, Jeanne-Marie R; Smith, Rebekah; Garvan, Cynthia Wilson; Wiens, Brenda; Cottler, Linda B

2015-05-01

Upon immigration to the rural areas in the US, Latino families may experience cultural, geographic, linguistic and social isolation, which can detrimentally affect their wellbeing by acting as chronic stressors. Using a community engagement approach, this is a pilot mixed-method study with an embedded design using concurrent qualitative and quantitative data. The purpose of this study is to evaluate family and social environments in terms of protective factors and modifiable risks associated with mental well-being in Latino immigrants living in rural areas of Florida. Latino immigrant mother and adolescent dyads were interviewed by using in-depth ethnographic semistructured interviews and subsequent quantitative assessments, including a demographic questionnaire and three structured instruments: the Family Environment Scale Real Form, the SF-12v2™ Health Survey and the short version (eight items) of PROMIS Health Organization Social Isolation. This mixed-method pilot study highlighted how family, rural, and social environments can protect or impair wellbeing in rural Latino immigrant mother and adolescent dyads.

Evaluation of empirical process design relationships for ozone disinfection of water and wastewater

DOE Office of Scientific and Technical Information (OSTI.GOV)

Finch, G.R.; Smith, D.W.

A research program was undertaken to examine the dose-response of Escherichia coli ATCC 11775 in ozone demand-free phosphate buffer solution and in a high quality secondary wastewater effluent with a total organic carbon content of 8 mg/L and a chemical oxygen demand of 26 mg/L. The studies were conducted in bench-scale batch reactors for both water types. In addition, studies using secondary effluent also were conducted in a pilot-scale, semi-batch reactor to evaluate scale-up effects. It was found that the ozone dose was the most important design parameter in both types of water. Contact time was of some importance inmore » the ozone demand-free water and had no detectable effect in the secondary effluent. Pilot-scale data confirmed the results obtained at bench-scale for the secondary effluent. Regression analysis of the logarithm of the E. coli response on the logarithm of the utilized ozone dose revealed that there was lack-of-fit using the model form which has been used frequently for the design of wastewater disinfection systems. This occurred as a result of a marked tailing effect of the log-log plot as the ozone dose increased and the kill increased. It was postulated that this was caused by some unknown physiological differences within the E. coli population due to age or another factor.« less

Ecotoxicity assessment of artificial groundwater recharge with reclaimed water: a pilot-scale study.

PubMed

Zhang, Xue; Zhao, Xuan

2013-11-01

A demonstration of artificial groundwater recharge with tertiary effluent was evaluated using a set of bioassays (acute toxicity to Daphnia, genotoxicity, estrogenic and antiestrogenic toxicity). Around 95 % genotoxicity and 53 % antiestrogenicity were removed from the feed water by ozonation, whereas significant reduction of acute toxicity to Daphnia magna was achieved during a 3 days vadose soil treatment. The toxicity was further removed to the same level as the local groundwater during a 20 days aquifer soil treatment. The pilot study has shown that ozonation and soil treatments can improve the quality of municipal wastewater treatment plant effluents for possible groundwater recharge purposes.

Performance of a pilot-scale constructed wetland system for treating simulated ash basin water.

PubMed

Dorman, Lane; Castle, James W; Rodgers, John H

2009-05-01

A pilot-scale constructed wetland treatment system (CWTS) was designed and built to decrease the concentration and toxicity of constituents of concern in ash basin water from coal-burning power plants. The CWTS was designed to promote the following treatment processes for metals and metalloids: precipitation as non-bioavailable sulfides, co-precipitation with iron oxyhydroxides, and adsorption onto iron oxides. Concentrations of Zn, Cr, Hg, As, and Se in simulated ash basin water were reduced by the CWTS to less than USEPA-recommended water quality criteria. The removal efficiency (defined as the percent concentration decrease from influent to effluent) was dependent on the influent concentration of the constituent, while the extent of removal (defined as the concentration of a constituent of concern in the CWTS effluent) was independent of the influent concentration. Results from toxicity experiments illustrated that the CWTS eliminated influent toxicity with regard to survival and reduced influent toxicity with regard to reproduction. Reduction in potential for scale formation and biofouling was achieved through treatment of the simulated ash basin water by the pilot-scale CWTS.

A numerical investigation of the scale-up effects on flow, heat transfer, and kinetics processes of FCC units.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chang, S. L.

1998-08-25

Fluid Catalytic Cracking (FCC) technology is the most important process used by the refinery industry to convert crude oil to valuable lighter products such as gasoline. Process development is generally very time consuming especially when a small pilot unit is being scaled-up to a large commercial unit because of the lack of information to aide in the design of scaled-up units. Such information can now be obtained by analysis based on the pilot scale measurements and computer simulation that includes controlling physics of the FCC system. A Computational fluid dynamic (CFD) code, ICRKFLO, has been developed at Argonne National Laboratorymore » (ANL) and has been successfully applied to the simulation of catalytic petroleum cracking risers. It employs hybrid hydrodynamic-chemical kinetic coupling techniques, enabling the analysis of an FCC unit with complex chemical reaction sets containing tens or hundreds of subspecies. The code has been continuously validated based on pilot-scale experimental data. It is now being used to investigate the effects of scaled-up FCC units. Among FCC operating conditions, the feed injection conditions are found to have a strong impact on the product yields of scaled-up FCC units. The feed injection conditions appear to affect flow and heat transfer patterns and the interaction of hydrodynamics and cracking kinetics causes the product yields to change accordingly.« less

Web-based physiotherapy for people moderately affected with Multiple Sclerosis; quantitative and qualitative data from a randomized, controlled pilot study.

PubMed

Paul, Lorna; Coulter, Elaine H; Miller, Linda; McFadyen, Angus; Dorfman, Joe; Mattison, Paul George G

2014-09-01

To explore the effectiveness and participant experience of web-based physiotherapy for people moderately affected with Multiple Sclerosis (MS) and to provide data to establish the sample size required for a fully powered, definitive randomized controlled study. A randomized controlled pilot study. Rehabilitation centre and participants' homes. Thirty community dwelling adults moderately affected by MS (Expanded Disability Status Scale 5-6.5). Twelve weeks of individualised web-based physiotherapy completed twice per week or usual care (control). Online exercise diaries were monitored; participants were telephoned weekly by the physiotherapist and exercise programmes altered remotely by the physiotherapist as required. The following outcomes were completed at baseline and after 12 weeks; 25 Foot Walk, Berg Balance Scale, Timed Up and Go, Multiple Sclerosis Impact Scale, Leeds MS Quality of Life Scale, MS-Related Symptom Checklist and Hospital Anxiety and Depression Scale. The intervention group also completed a website evaluation questionnaire and interviews. Participants reported that website was easy to use, convenient, and motivating and would be happy to use in the future. There was no statistically significant difference in the primary outcome measure, the timed 25ft walk in the intervention group (P=0.170), or other secondary outcome measures, except the Multiple Sclerosis Impact Scale (P=0.048). Effect sizes were generally small to moderate. People with MS were very positive about web-based physiotherapy. The results suggested that 80 participants, 40 in each group, would be sufficient for a fully powered, definitive randomized controlled trial. © The Author(s) 2014.

"In-Situ Chemical Oxidation" - Sessions: #6 Technology Development, Process Fundamentals, Mechanisms;#7 Advantages and Disadvantages; #9 Oxidant Selection; #10 Bench- and Pilot-Scale Studies; #11 Monitoring; #12 Field-Scale Implementation; #13 Chemical Oxidation Regeneration of Granular Activated Carbon

EPA Science Inventory

A series of seven technical presentations involving chemical oxidation will be given to faculty, graduate students, and environmental professionals at the Chinese Academy of Sciences in Beijing, China (April 21-22, 2010). Chemical oxidation technologies include in-situ chemical o...

Simulating the Effects of Spread of Electric Excitation on Musical Tuning and Melody Identification with a Cochlear Implant

ERIC Educational Resources Information Center

Spahr, Anthony J.; Litvak, Leonid M.; Dorman, Michael F.; Bohanan, Ashley R.; Mishra, Lakshmi N.

2008-01-01

Purpose: To determine why, in a pilot study, only 1 of 11 cochlear implant listeners was able to reliably identify a frequency-to-electrode map where the intervals of a familiar melody were played on the correct musical scale. The authors sought to validate their method and to assess the effect of pitch strength on musical scale recognition in…

Teacher Beliefs, Teacher Concerns, and School Leadership Support as Influences on School Readiness for Implementing a Research-Based Reform Model

ERIC Educational Resources Information Center

Carhart, Elizabeth Hoag

2013-01-01

Federal policy makers and school leaders increasingly recognize middle school math as a turning point in students' academic success. An i3 scale-up grant allowed grant partners to conduct a large-scale implementation of PowerTeaching (PT), a research-based reform to increase student math achievement. In a mixed-methods study during the pilot phase…

Estimation of Hydraulic Parameters and Aquifer Properties for a Managed Aquifer Recharge Pilot Study in The Lower Mississippi River Basin

NASA Astrophysics Data System (ADS)

Ozeren, Y.; Rigby, J.; Holt, R. M.

2017-12-01

Mississippi River Valley Alluvial Aquifer (MRVAA) is the major irrigation water resource in the in the lower Mississippi River basin. MRVAA has been significantly depleted in the last two decades due to excessive pumping. A wide range of measures to ensure sustainable groundwater supply in the region is currently under investigation. One of the possible solution under consideration is to use Managed Aquifer Recharge (MAR) by artificial recharge. The proposed artificial recharge technique in this study is to collect water through bank filtration, transfer water via pipeline to the critically low groundwater areas by a set of injection wells. A pilot study in the area is underway to investigate the possibility of artificial recharge in the area. As part of this study, a pumping test was carried out on an existing irrigation well along banks of Tallahatchie River near Money, MS. Geophysical surveys were also carried out in the pilot study area. Hydraulic response of the observation wells was used to determine stream bed conductance and aquifer parameters. The collected hydraulic parameters and aquifer properties will provide inputs for small-scale, high-resolution engineering model for abstraction-injection hydraulics along river. Here, preliminary results of the pilot study is presented.

Assessment of personality-related levels of functioning: a pilot study of clinical assessment of the DSM-5 level of personality functioning based on a semi-structured interview.

PubMed

Thylstrup, Birgitte; Simonsen, Sebastian; Nemery, Caroline; Simonsen, Erik; Noll, Jane Fjernestad; Myatt, Mikkel Wanting; Hesse, Morten

2016-08-25

The personality disorder categories in the Diagnostic and Statistical Manual of Mental Disorders IV have been extensively criticized, and there is a growing consensus that personality pathology should be represented dimensionally rather than categorically. The aim of this pilot study was to test the Clinical Assessment of the Level of Personality Functioning Scale, a semi-structured clinical interview, designed to assess the Level of Personality Functioning Scale of the DSM-5 (Section III) by applying strategies similar to what characterizes assessments in clinical practice. The inter-rater reliability of the assessment of the four domains and the total impairment in the Level of Personality Functioning Scale were measured in a patient sample that varied in terms of severity and type of pathology. Ratings were done independently by the interviewer and two experts who watched a videotaped Clinical Assessment of the Level of Personality Functioning Scale interview. Inter-rater reliability coefficients varied between domains and were not sufficient for clinical practice, but may support the use of the interview to assess the dimensions of personality functioning for research purposes. While designed to measure the Level of Personality Functioning Scale with a high degree of similarity to clinical practice, the Clinical Assessment of the Level of Personality Functioning Scale had weak reliabilities and a rating based on a single interview should not be considered a stand-alone assessment of areas of functioning for a given patient.

Increasing Access to Mental Health Care With Breathe, an Internet-Based Program for Anxious Adolescents: Study Protocol for a Pilot Randomized Controlled Trial

PubMed Central

Wozney, Lori; Bagnell, Alexa; Fitzpatrick, Eleanor; Curtis, Sarah; Jabbour, Mona; Johnson, David; Rosychuk, Rhonda J; Young, Michael; Ohinmaa, Arto; Joyce, Anthony; McGrath, Patrick

2016-01-01

Background There is a demand to make first-line treatments, including cognitive behavioural therapy (CBT) for adolescent anxiety disorders, more widely available. Internet-based CBT is proposed to circumvent access and availability barriers and reduce health care system costs. Recent reviews suggest more evidence is needed to establish the treatment effects of Internet-based CBT in children and adolescents and to determine related economic impacts. Objective This pilot trial aims to collect the necessary data to inform the planning of a full-scale RCT to test the effectiveness of the Internet-based CBT program Breathe (Being Real, Easing Anxiety: Tools Helping Electronically). Methods We are conducting a 27-month, 2-arm parallel-group, pilot randomized controlled trial (RCT). Outcomes will inform the planning of a full-scale RCT aimed to test the effectiveness of Internet-based CBT with a population of adolescents with moderate to mild anxiety problems. In the pilot RCT we will: (1) define a minimal clinically important difference (MCID) for the primary outcome measure (total anxiety score using the Multidimensional Anxiety Scale for Children); (2) determine a sample size for the full-scale RCT; (3) estimate recruitment and retention rates; (4) measure intervention acceptability to inform critical intervention changes; (5) determine the use of co-interventions; and (6) conduct a cost-consequence analysis to inform a cost-effectiveness analysis in the full-scale RCT. Adolescents aged 13-17 years seeking care for an anxiety complaint from a participating emergency department, mobile or school-based crisis team, or primary care clinic are being screened for interest and eligibility. Enrolled adolescents are being randomly allocated to either 8 weeks of Internet-based CBT with limited telephone and e-mail support, or a control group with access to a static webpage listing anxiety resources. Adolescents are randomly assigned using a computer generated allocation sequence. Data are being collected at baseline, treatment completion, and at a 3-month follow-up. Results Currently, adolescents are being enrolled in the study. Enrolment is taking place between March 2014 and February 2016; data collection will conclude May 2016. We expect that analysis and results will be available by August 2016. Conclusions In many communities, the resources available for front-line anxiety treatment are outweighed by the need for care. This pilot RCT is an essential step to designing a robust RCT to evaluate the effectiveness of an Internet-based CBT program for adolescents with moderate to mild anxiety problems. Trial Registration Clinicaltrials.gov NCT02059226; http://clinicaltrials.gov/ct2/show/NCT02059226 (Archived by WebCite at http://www.webcitation.org/6epF8v7k4) PMID:26825111

Combustion characteristics of paper and sewage sludge in a pilot-scale fluidized bed.

PubMed

Yu, Yong-Ho; Chung, Jinwook

2015-01-01

This study characterizes the combustion of paper and sewage sludge in a pilot-scale fluidized bed. The highest temperature during combustion within the system was found at the surface of the fluidized bed. Paper sludge containing roughly 59.8% water was burned without auxiliary fuel, but auxiliary fuel was required to incinerate the sewage sludge, which contained about 79.3% water. The stability of operation was monitored based on the average pressure and the standard deviation of pressure fluctuations. The average pressure at the surface of the fluidized bed decreased as the sludge feed rate increased. However, the standard deviation of pressure fluctuations increased as the sludge feed rate increased. Finally, carbon monoxide (CO) emissions decreased as oxygen content increased in the flue gas, and nitrogen oxide (NOx) emissions were also tied with oxygen content.

Cognitive behavioral therapy for compulsive buying disorder.

PubMed

Mitchell, James E; Burgard, Melissa; Faber, Ron; Crosby, Ross D; de Zwaan, Martina

2006-12-01

To our knowledge, no psychotherapy treatment studies for compulsive buying have been published. The authors conducted a pilot trial comparing the efficacy of a group cognitive behavioral intervention designed for the treatment of compulsive buying to a waiting list control. Twenty-eight subjects were assigned to receive active treatment and 11 to the waiting list control group. The results at the end of treatment showed significant advantages for cognitive behavioral therapy (CBT) over the waiting list in reductions in the number of compulsive buying episodes and time spent buying, as well as scores on the Yale-Brown Obsessive Compulsive Scale--Shopping Version and the Compulsive Buying Scale. Improvement was well-maintained at 6-month follow-up. The pilot data suggests that a cognitive behavioral intervention can be quite effective in the treatment of compulsive buying disorder. This model requires further testing.

Pilot scale thin film plate reactors for the photocatalytic treatment of sugar refinery wastewater.

PubMed

Saran, S; Kamalraj, G; Arunkumar, P; Devipriya, S P

2016-09-01

Pilot scale thin film plate reactors (TFPR) were fabricated to study the solar photocatalytic treatment of wastewater obtained from the secondary treatment plant of a sugar refinery. Silver-impregnated titanium dioxide (TiO2) was prepared by a facile chemical reduction method, characterized, and immobilized onto the surface of ceramic tiles used in the pilot scale reactors. On 8 h of solar irradiation, percentage reduction of chemical oxygen demand (COD) of the wastewater by Ag/TiO2, pure TiO2, and control (without catalyst) TFPR was about 95, 86, and 22 % respectively. The effects of operational parameters such as, flow rate, pH, and addition of hydrogen peroxide (H2O2) were optimized as they influence the rate of COD reduction. Under 3 h of solar irradiation, 99 % COD reduction was observed at an optimum flow rate of 15 L h(-1), initial pH of 2, and addition of 5 mM of H2O2. The results show that Ag/TiO2 TFPR could be effectively used for the tertiary treatment of sugar refinery effluent using sunlight as the energy source. The treated water could be reused for industrial purposes, thus reducing the water footprint of the industry. Graphical Abstract Sugar refinery effluent treatment by solar photocatalytic TFPR.

Design of the Blood Pressure Goals in Dialysis pilot study.

PubMed

Gul, Ambreen; Miskulin, Dana; Gassman, Jennifer; Harford, Antonia; Horowitz, Bruce; Chen, Joline; Paine, Susan; Bedrick, Edward; Kusek, John W; Unruh, Mark; Zager, Philip

2014-02-01

Cardiovascular disease (CVD) is markedly increased among hemodialysis (HD) patients. Optimizing blood pressure (BP) among HD patients may present an important opportunity to reduce the disparity in CVD rates between HD patients and the general population. The optimal target predialysis systolic BP (SBP) among HD patients is unknown. Current international guidelines, calling for a predialysis SBP < 140 mm Hg, are based on the opinion and extrapolation from the general population. Existing randomized controlled trials (RCTs) were small and did not include prespecified BP targets. The authors described the design of the Blood Pressure in Dialysis (BID) Study, a pilot, multicenter RCT where HD patients are randomized to either a target-standardized predialysis SBP of 110 to 140 mm Hg or 155 to 165 mm Hg. This is the first study to randomize HD patients to 2 different SBP targets. Primary outcomes are feasibility and safety. Feasibility parameters include recruitment and retention rates, adherence with prescribed BP measurements and achievement and maintenance of selected BP targets. Safety parameters include rates of hypotension and other adverse and serious adverse events. The authors obtained preliminary data on changes in left ventricular mass, aortic pulse wave velocity, vascular access thromboses and health-related quality of life across study arms, which may be the secondary outcomes in the full-scale study. The data acquired in the pilot RCT will determine the feasibility and safety and inform the design of a full-scale trial, powered for hard outcomes, which may require 2000 participants.

FIELD EVALUATION OF SOLVENT EXTRACTION RESIDUAL BIOTREATMENT (SERB)

EPA Science Inventory

Laboratory and pilot-scale studies have demonstrated that cosolvent-enhanced in situ extraction can remove residual and free-phase nonaqueous phase liquid (NAPL), but may leave levels of contaminants in the ground water and subsurface formations in excess of the regulatory requir...

WATER FILTRATION AT DULUTH

EPA Science Inventory

After partial completion of the Lakewood Filtration Plant at Duluth, studies were begun with funding provided by the demonstration grant. Research covered a variety of topics and was done with a 10 gpm pilot plant located at the filtration plant, with the full scale plant operati...

EVALUATION OF ANALYTICAL METHODS FOR DETERMINING PESTICIDES IN FOODS

EPA Science Inventory

Children can be exposed to pesticides by inhaling contaminated air, ingesting tainted food or non-dietary substances, or absorbing them through the skin from contaminated media. Earlier pilot-scale exposure studies suggest that dietary ingestion is an important pathway for chi...

POLISHING EFFLUENT FROM A PERCHLORATE-REDUCING ANAEROBIC BIOLOGICAL CONTACTOR

EPA Science Inventory

The U.S. Environmental Protection Agency undertook at 3 ½ year pilot-scale biological perchlorate treatment study that included two long (311 and 340 days) examinations of anaerobic effluent polishing. The polishing system consisted of hydrogen peroxide addition and aeration, fo...

Influence of voltage input to heavy metal removal from electroplating wastewater using electrocoagulation process

NASA Astrophysics Data System (ADS)

Wulan, D. R.; Cahyaningsih, S.; Djaenudin

2017-03-01

In medium capacity, electroplating industry usually treats wastewater until 5 m3 per day. Heavy metal content becomes concern that should be reduced. Previous studies performed electrocoagulation method on laboratory scale, either batch or continuous. This study was aimed to compare the influence of voltage input variation into heavy metal removal in electroplating wastewater treatment using electrocoagulation process on laboratory-scale in order to determine the optimum condition for scaling up the reactor into pilot-scale. The laboratory study was performed in 1.5 L glass reactor in batch system using wastewater from electroplating industry, the voltage input varied at 20, 30 and 40 volt. The electrode consisted of aluminium 32 cm2 as sacrifice anode and copper 32 cm2 as cathode. During 120 min electrocoagulation process, the pH value was measured using pH meter, whereas the heavy metal of chromium, copper, iron, and zinc concentration were analysed using Atomic Absorption Spectrophotometer (AAS). Result showed that removal of heavy metals from wastewater increased due to the increasing of voltage input. Different initial concentration of heavy metals on wastewater, resulted the different detention time. At pilot-scale reactor with 30 V voltage input, chromium, iron, and zinc reached removal efficiency until 89-98%, when copper reached 79% efficiency. At 40V, removal efficiencies increased on same detention time, i.e. chromium, iron, and zinc reached 89-99%, whereas copper reached 85%. These removal efficiencies have complied the government standard except for copper that had higher initial concentration in wastewater. Kinetic rate also calculated in this study as the basic factor for scaling up the process.

UTILIZATION OF TREATABILITY AND PILOT TESTS TO PREDICT CAH BIOREMEDIATION

EPA Science Inventory

Multiple tools have been suggested to help in the design of enhanced anaerobic bioremediation systems for CAHs:
- Extensive high quality microcosm testing followed by small-scale, thoroughly observed field pilot tests (i.e., RABITT Protocol, Morse 1998)
- More limited ...

Bioretention for stormwater quality improvement in Texas : pilot experiments.

DOT National Transportation Integrated Search

2010-07-01

This report summarizes the results of pilot-scale bioretention experiments. Five steel boxes of 6 ft (L) 6 ft : (W) 4 ft (D) were constructed, each of which has a different type of vegetation: (1) shrubs, (2) grass : species in Texas Department...

Mobile Technology Application for Improved Urine Concentration Measurement Pilot Study.

PubMed

Walawender, Laura; Patterson, Jeremy; Strouse, Robert; Ketz, John; Saxena, Vijay; Alexy, Emily; Schwaderer, Andrew

2018-01-01

Objectives: Low hydration has a deleterious effect on many conditions. In the absence of a urine concentrating defect, urine concentration is a marker of hydration status. However, markers to evaluate hydration status have not been well studied in children. The objectives of this paper are to compare measures of thirst and urine concentration in children and to develop a novel mobile technology application to measure urine concentration. Study Design: Children age 12-17 years were selected ( n = 21) for this pilot study. Thirst perception, specific gravity (automated dipstick analysis and refractometer), and urine color scale results were correlated to urine osmolality. The technology department developed a mobile technology camera application to measure light penetrance into urine which was tested on 25 random anonymized urine samples. Results: The patients' thirst perception and color scale as well as two researchers color scale did not significantly correlate with osmolality. Correlation between osmolality and hydration markers resulted in the following Pearson coefficients: SG automated dipstick, 0.61 ( P 0.003); SG refractometer, 0.98 ( P < 0.0001); urine color scale (patient), 0.37 ( P 0.10), and light penetrance, -0.77 ( P < 0.0001). The correlation of light penetrance with osmolality was stronger than all measures except SG by refractometer and osmolality. Conclusion: The mobile technology application may be a more accurate tool for urine concentration measurement than specific gravity by automated dipstick, subjective thirst, and urine color scale, but lags behind specific gravity measured by refractometer. The mobile technology application is a step toward patient oriented hydration strategies.

A pilot study to understand feasibility and acceptability of stool and cord blood sample collection for a large-scale longitudinal birth cohort.

PubMed

Bailey, S R; Townsend, C L; Dent, H; Mallet, C; Tsaliki, E; Riley, E M; Noursadeghi, M; Lawley, T D; Rodger, A J; Brocklehurst, P; Field, N

2017-12-28

Few data are available to guide biological sample collection around the time of birth for large-scale birth cohorts. We are designing a large UK birth cohort to investigate the role of infection and the developing immune system in determining future health and disease. We undertook a pilot to develop methodology for the main study, gain practical experience of collecting samples, and understand the acceptability of sample collection to women in late pregnancy. Between February-July 2014, we piloted the feasibility and acceptability of collecting maternal stool, baby stool and cord blood samples from participants recruited at prolonged pregnancy and planned pre-labour caesarean section clinics at University College London Hospital. Participating women were asked to complete acceptability questionnaires. Overall, 265 women were approached and 171 (65%) participated, with ≥1 sample collected from 113 women or their baby (66%). Women had a mean age of 34 years, were primarily of white ethnicity (130/166, 78%), and half were nulliparous (86/169, 51%). Women undergoing planned pre-labour caesarean section were more likely than those who delivered vaginally to provide ≥1 sample (98% vs 54%), but less likely to provide maternal stool (10% vs 43%). Pre-sample questionnaires were completed by 110/171 women (64%). Most women reported feeling comfortable with samples being collected from their baby (<10% uncomfortable), but were less comfortable about their own stool (19% uncomfortable) or a vaginal swab (24% uncomfortable). It is possible to collect a range of biological samples from women around the time of delivery, and this was acceptable for most women. These data inform study design and protocol development for large-scale birth cohorts.

Evaluating off-campus student housing preferences: A pilot survey

NASA Astrophysics Data System (ADS)

Johari, Noraini; Mohd, Thuraiya; Abdullah, Lizawati; Ahmad@Mohamed, Nurulanis; Sani, Suwaibatul Islamiah Abdullah

2017-10-01

In recent decades, the term student housing has been highlighted as a body of knowledge in housing studies. In providing better quality of life, student housing evolved into a critical agenda in developing higher education learning. This research paper aims to discuss on a pilot study examining student housing preferences among university and college students should they reside off-campus. The research aims at identifying the attributes of off-campus student housing preferences to give a significant input for the development of an off-campus student housing preferences conceptual framework. This research is a cross-sectional study in which survey participants are currently-enrolled students throughout the period of survey. During this pilot study, questionnaires were distributed among university students in Shah Alam, Selangor in Malaysia. A total of 86 survey questionnaires were collected, consisting of questions reflecting students' background, Likert scale questions to specify their preferences, and open-ended questions. This preliminary pilot result shows that the 46 variables student housing preferences have a good reliability and validity. The outcomes from this research provide insight into students' preferences on how off-campus housing should be developed. Since Selangor is divided into various districts with a plethora of different local contexts including different university campuses, there is a need for further study to avoid generalization.

Adjunctive low-dose docosahexaenoic acid (DHA) for major depression: An open-label pilot trial.

PubMed

Smith, Deidre J; Sarris, Jerome; Dowling, Nathan; O'Connor, Manjula; Ng, Chee H

2018-04-01

Whilst the majority of evidence supports the adjunctive use of eicosapentaenoic acid (EPA) in improving mood, to date no study exists using low-dose docosahexaenoic acid (DHA) alone as an adjunctive treatment in patients with mild to moderate major depressive disorder (MDD). A naturalistic 8-week open-label pilot trial of low-dose DHA, (260 mg or 520 mg/day) in 28 patients with MDD who were non-responsive to medication or psychotherapy, with a Hamilton Depression Rating Scale (HAM-D) score of greater than 17, was conducted. Primary outcomes of depression, clinical severity, and daytime sleepiness were measured. After 8 weeks, 54% of patients had a ≥50% reduction on the HAM-D, and 45% were in remission (HAM-D ≤ 7). The eta-squared statistic (0.59) indicated a large effect size for the reduction of depression (equivalent to Cohen's d of 2.4). However confidence in this effect size is tempered due to the lack of a placebo. The mean score for the Clinical Global Impression Severity Scale was significantly improved by 1.28 points (P < 0.05). Despite a significant reduction in the HAM-D score for middle insomnia (P = 0.02), the reduction in excessive daytime somnolence on the total Epworth Sleepiness Scale (ESS) did not reach significance. No significant adverse reactions to DHA were found. Within the major limits of this open-label pilot study, the results suggest that DHA may provide additional adjunctive benefits in patients with mild- to -moderate depression.

Effectiveness of ethics education as perceived by nursing students: development and testing of a novel assessment instrument.

PubMed

Vynckier, Tine; Gastmans, Chris; Cannaerts, Nancy; de Casterlé, Bernadette Dierckx

2015-05-01

The effectiveness of ethics education continues to be disputed. No studies exist on how nursing students perceive the effectiveness of nursing ethics education in Flanders, Belgium. To develop a valid and reliable instrument, named the 'Students' Perceived Effectiveness of Ethics Education Scale' (SPEEES), to measure students' perceptions of the effectiveness of ethics education, and to conduct a pilot study in Flemish nursing students to investigate the perceived efficacy of nursing ethics education in Flanders. Content validity, comprehensibility and usability of the SPEEES were assessed. Reliability was assessed by means of a quantitative descriptive non-experimental pilot study. 86 third-year baccalaureate nursing students of two purposefully selected university colleges answered the SPEEES. Formal approval was given by the ethics committee. Informed consent was obtained and anonymity was ensured for both colleges and their participating students. The scale content validity index/Ave scores for the subscales were 1.00, 1.00 and 0.86. The comprehensibility and user-friendliness were favourable. Cronbach's alpha was 0.94 for general effectiveness, 0.89 for teaching methods and 0.85 for ethical content. Students perceived 'case study', 'lecture' and 'instructional dialogue' to be effective teaching methods and 'general ethical concepts' to contain effective content. 'Reflecting critically on their own values' was mentioned as the only ethical competence that, was promoted by the ethics courses. The study revealed rather large differences between both schools in students' perceptions of the contribution of ethics education to other ethical competences. The study revealed that according to the students, ethics courses failed to meet some basic objectives of ethics education. Although the SPEEES proved to be a valid and reliable measure, the pilot study suggests that there is still space for improvement and a need for larger scale research. Additional insights will enable educators to improve current nursing ethics education. © The Author(s) 2014.

Assessing communication skills of clinical call handlers working at an out-of-hours centre: development of the RICE rating scale.

PubMed

Derkx, Hay P; Rethans, Jan-Joost E; Knottnerus, J André; Ram, Paul M

2007-05-01

Out-of-hours centres provide telephone support to patients with medical problems. In most of these centres specially-trained nurses handle incoming telephone calls. They assess patients' needs, the degree of urgency, and determine the level of care required. Assessment of the medical problem and the quality of 'care-by-phone' depend on the medical and communication skills of the call handlers. To develop a valid, reliable, and practical rating scale to evaluate the communication skills of call handlers working at an out-of-hours centre and to improve quality of communication. Qualitative study with focus groups followed by validation of the rating scale and measurement of reliability (internal consistency). Out-of-hours centres in the Netherlands. A focus group developed the rating scale. Experts with experience in training and evaluating communication skills of medical students and GPs commented on the scale to ensure content validity. The reliability of the rating scale was tested in a pilot in which ten specially-trained assessors scored six telephone calls each. The scale, known as the RICE rating scale, has 17 items divided over four different phases of the telephone consultation: Reason for calling; Information gathering; Conclusion; and Evaluation (RICE). Content validity of the scale was assessed by two experts. Reliability of the scale tested in the pilot was 0.73 (Cronbach's alpha). Establishing a rating scale to assess the communication skills of call handlers which meets common scientific demands, such as content validity and reliability, proved successful. This instrument can be used to give feedback to call handlers.

Watershed management contributions to land stewardship: Case studies in the Southeast

Treesearch

Wayne T. Swank; David R. Tilley

2000-01-01

We describe three examples of watershed management studies, at different spatial scales, that provide approaches and information useful in enhancing natural resource stewardship in the southern Appalachians. A multiple use “pilot” study, initiated 35 years ago at the Coweeta Hydrologic Laboratory, demonstrates that southern Appalachian forests can be successfully...

Implementation of an Evidence-Based Seizure Algorithm in Intellectual Disability Nursing: A Pilot Study

ERIC Educational Resources Information Center

Auberry, Kathy; Cullen, Deborah

2016-01-01

Based on the results of the Surrogate Decision-Making Self Efficacy Scale (Lopez, 2009a), this study sought to determine whether nurses working in the field of intellectual disability (ID) experience increased confidence when they implemented the American Association of Neuroscience Nurses (AANN) Seizure Algorithm during telephone triage. The…

How Information Affects Intrinsic Motivation: Two Exploratory Pilot Studies.

ERIC Educational Resources Information Center

Small, Ruth V.; Samijo

Research on the motivational aspects of multimedia games may provide ways to design more engaging user information systems which increase users' exploratory and information-seeking behaviors. Two small-scale exploratory studies examined the effects of introducing information on the intrinsic motivation of users of a CD-ROM game. Results of the…

Music for surgical abortion care study: a randomized controlled pilot study.

PubMed

Wu, Justine; Chaplin, William; Amico, Jennifer; Butler, Mark; Ojie, Mary Jane; Hennedy, Dina; Clemow, Lynn

2012-05-01

The study objective was to explore the effect of music as an adjunct to local anesthesia on pain and anxiety during first-trimester surgical abortion. Secondary outcomes included patient satisfaction and coping. We conducted a randomized controlled pilot study of 26 women comparing music and local anesthesia to local anesthesia alone. We assessed pain, anxiety and coping with 11-point verbal numerical scales. Patient satisfaction was measured via a 4-point Likert scale. In the music group, we noted a trend toward a faster decline in anxiety postprocedure (p=.065). The music group reported better coping than the control group (mean±S.D., 8.5±2.3 and 6.2±2.8, respectively; p<.05). Both groups reported similarly high satisfaction scores. There were no group differences in pain. Music as an adjunct to local anesthesia during surgical abortion is associated with a trend toward less anxiety postprocedure and better coping while maintaining high patient satisfaction. Music does not appear to affect abortion pain. Copyright © 2012 Elsevier Inc. All rights reserved.

CFD Modeling of Flow, Temperature, and Concentration Fields in a Pilot-Scale Rotary Hearth Furnace

NASA Astrophysics Data System (ADS)

Liu, Ying; Su, Fu-Yong; Wen, Zhi; Li, Zhi; Yong, Hai-Quan; Feng, Xiao-Hong

2014-01-01

A three-dimensional mathematical model for simulation of flow, temperature, and concentration fields in a pilot-scale rotary hearth furnace (RHF) has been developed using a commercial computational fluid dynamics software, FLUENT. The layer of composite pellets under the hearth is assumed to be a porous media layer with CO source and energy sink calculated by an independent mathematical model. User-defined functions are developed and linked to FLUENT to process the reduction process of the layer of composite pellets. The standard k-ɛ turbulence model in combination with standard wall functions is used for modeling of gas flow. Turbulence-chemistry interaction is taken into account through the eddy-dissipation model. The discrete ordinates model is used for modeling of radiative heat transfer. A comparison is made between the predictions of the present model and the data from a test of the pilot-scale RHF, and a reasonable agreement is found. Finally, flow field, temperature, and CO concentration fields in the furnace are investigated by the model.

High power Nb-doped LiFePO4 Li-ion battery cathodes; pilot-scale synthesis and electrochemical properties

NASA Astrophysics Data System (ADS)

Johnson, Ian D.; Blagovidova, Ekaterina; Dingwall, Paul A.; Brett, Dan J. L.; Shearing, Paul R.; Darr, Jawwad A.

2016-09-01

High power, phase-pure Nb-doped LiFePO4 (LFP) nanoparticles are synthesised using a pilot-scale continuous hydrothermal flow synthesis process (production rate of 6 kg per day) in the range 0.01-2.00 at% Nb with respect to total transition metal content. EDS analysis suggests that Nb is homogeneously distributed throughout the structure. The addition of fructose as a reagent in the hydrothermal flow process, followed by a post synthesis heat-treatment, affords a continuous graphitic carbon coating on the particle surfaces. Electrochemical testing reveals that cycling performance improves with increasing dopant concentration, up to a maximum of 1.0 at% Nb, for which point a specific capacity of 110 mAh g-1 is obtained at 10 C (6 min for the charge or discharge). This is an excellent result for a high power cathode LFP based material, particularly when considering the synthesis was performed on a large pilot-scale apparatus.

A qualitative analysis of bus simulator training on transit incidents : a case study in Florida. [Summary].

DOT National Transportation Integrated Search

2013-01-01

The simulator was once a very expensive, large-scale mechanical device for training military pilots or astronauts. Modern computers, linking sophisticated software and large-screen displays, have yielded simulators for the desktop or configured as sm...

APPLICATION OF THE PERMEABLE REACTIVE BARRIER TECHNOLOGY FOR THE TREATMENT OF ARSENIC IN GROUND WATER

EPA Science Inventory

The research approach will involve hydrogeological and geochemical studies to provide information needed in order to select an appropriate design configuration and to evaluate the performance of a pilot-scale subsurface permeable reactive barrier to remediate arsenic-contaminated...

PILOT-SCALE EVALUATION OF AN INCINERABILITY RANKING SYSTEM FOR HAZARDOUS ORGANIC COMPOUNDS

EPA Science Inventory

The subject study was conducted to evaluate an incinerability ranking system developed by teh University of Dayton Research Institute under contract to the EPA Risk Reduction Engineering Laboratory. Fixtures of organic compounds were prepared and combined with a clay-based sorben...

EPA'S REGIONAL VULNERABILITY ASSESSMENT PROGRAM (REVA) DEMONSTRATING RESULTS THROUGH PARTNERSHIPS

EPA Science Inventory

EPA's Regional Vulnerability Assessment (ReVA) program, a regional-scale comparative risk research effort, has been under development since 1998 with a pilot study focused on the Mid- Atlantic region. ReVA is part of the interagency Integrated Science for Ecosystem Challenges ini...

Composting Begins at Home.

ERIC Educational Resources Information Center

Dreckman, George P.

1994-01-01

Reports the results of a year-long home composting pilot program run by the city of Madison, Wisconsin. The study was designed to gather data on the amount and type of materials composted by 300 volunteer households and to determine the feasibility of a full-scale program. (LZ)

Intro to NREL's Thermochemical Pilot Plant

ScienceCinema

Magrini, Kim

2018-02-13

NREL's Thermochemical Pilot Plant converts biomass into higher hydrocarbon fuels and chemicals.NREL is researching biomass pyrolysis. The lab is examining how to upgrade bio-oils via stabilization. Along with this, NREL is developing the engineering system requirements for producing these fuels and chemicals at larger scales.

UTILIZATION OF TREATABILITY AND PILOT TESTS TO PREDICT CAH BIOREMEDIATION (Battelle)

EPA Science Inventory

Multiple tools have been suggested to help in the design of enhanced anaerobic bioremediation systems for CAHs:
Extensive high quality microcosm testing followed by small-scale, thoroughly observed, induced flow field pilot tests (i.e. RABITT Protocol, Morse 1998)
More...

CONTROL OF CRYPTOSPORIDIUM OOCYSTS BY STEADY-STATE CONVENTIONAL TREATMENT

EPA Science Inventory

Pilot-scale experiments have been performed to assess the ability of conventional treatment to control Cryptosporidium oocysts under steady-state conditions. The work was performed with a pilot plant that was designed to minimize flow rates and, as a result, the number of oocyst...

In-Flight Validation of a Pilot Rating Scale for Evaluating Failure Transients in Electronic Flight Control Systems

NASA Technical Reports Server (NTRS)

Kalinowski, Kevin F.; Tucker, George E.; Moralez, Ernesto, III

2006-01-01

Engineering development and qualification of a Research Flight Control System (RFCS) for the Rotorcraft Aircrew Systems Concepts Airborne Laboratory (RASCAL) JUH-60A has motivated the development of a pilot rating scale for evaluating failure transients in fly-by-wire flight control systems. The RASCAL RFCS includes a highly-reliable, dual-channel Servo Control Unit (SCU) to command and monitor the performance of the fly-by-wire actuators and protect against the effects of erroneous commands from the flexible, but single-thread Flight Control Computer. During the design phase of the RFCS, two piloted simulations were conducted on the Ames Research Center Vertical Motion Simulator (VMS) to help define the required performance characteristics of the safety monitoring algorithms in the SCU. Simulated failures, including hard-over and slow-over commands, were injected into the command path, and the aircraft response and safety monitor performance were evaluated. A subjective Failure/Recovery Rating (F/RR) scale was developed as a means of quantifying the effects of the injected failures on the aircraft state and the degree of pilot effort required to safely recover the aircraft. A brief evaluation of the rating scale was also conducted on the Army/NASA CH-47B variable stability helicopter to confirm that the rating scale was likely to be equally applicable to in-flight evaluations. Following the initial research flight qualification of the RFCS in 2002, a flight test effort was begun to validate the performance of the safety monitors and to validate their design for the safe conduct of research flight testing. Simulated failures were injected into the SCU, and the F/RR scale was applied to assess the results. The results validate the performance of the monitors, and indicate that the Failure/Recovery Rating scale is a very useful tool for evaluating failure transients in fly-by-wire flight control systems.

Watching Grass - a Pilot Study on the Suitability of Photogrammetric Techniques for Quantifying Change in Aboveground Biomass in Grassland Experiments

NASA Astrophysics Data System (ADS)

Kröhnert, M.; Anderson, R.; Bumberger, J.; Dietrich, P.; Harpole, W. S.; Maas, H.-G.

2018-05-01

Grassland ecology experiments in remote locations requiring quantitative analysis of the biomass in defined plots are becoming increasingly widespread, but are still limited by manual sampling methodologies. To provide a cost-effective automated solution for biomass determination, several photogrammetric techniques are examined to generate 3D point cloud representations of plots as a basis, to estimate aboveground biomass on grassland plots, which is a key ecosystem variable used in many experiments. Methods investigated include Structure from Motion (SfM) techniques for camera pose estimation with posterior dense matching as well as the usage of a Time of Flight (TOF) 3D camera, a laser light sheet triangulation system and a coded light projection system. In this context, plants of small scales (herbage) and medium scales are observed. In the first pilot study presented here, the best results are obtained by applying dense matching after SfM, ideal for integration into distributed experiment networks.

Temperament and risk for exercise dependence: results of a pilot study in female patients with eating disorders compared to elite athletes.

PubMed

Müller, Astrid; Claes, Laurence; Wos, Katharina; Kerling, Arno; Wünsch-Leiteritz, Wally; Cook, Brian; de Zwaan, Martina

2015-01-01

The present pilot study investigated the relationship between temperament and the risk for exercise dependence (EXD). A total of 32 female patients with eating disorders (potentially at risk for secondary EXD) and 29 female elite athletes without eating disturbances (potentially at risk for primary EXD) answered the Eating Disorder Examination-Questionnaire (EDE-Q), the Exercise Dependence Scale-German version (EDS-G), the Behavioral Inhibition System/Behavioral Activation System (BIS/BAS) scales, and the effortful control subscale of the Adult Temperament Questionnaire (ATQ-EC). There were significant positive correlations of the EDS-G with the BIS in women with an eating disorder and with the BAS in elite athletes. No significant association was found between the EDS-G and effortful control. The results indicate that the risk for EXD is associated with avoidance tendencies in women with eating disorders and with approach tendencies in elite athletes. Implications for secondary and primary EXD are discussed. © 2015 S. Karger AG, Basel.

Development and initial validation of an Aviation Safety Climate Scale.

PubMed

Evans, Bronwyn; Glendon, A Ian; Creed, Peter A

2007-01-01

A need was identified for a consistent set of safety climate factors to provide a basis for aviation industry benchmarking. Six broad safety climate themes were identified from the literature and consultations with industry safety experts. Items representing each of the themes were prepared and administered to 940 Australian commercial pilots. Data from half of the sample (N=468) were used in an exploratory factor analysis that produced a 3-factor model of Management commitment and communication, Safety training and equipment, and Maintenance. A confirmatory factor analysis on the remaining half of the sample showed the 3-factor model to be an adequate fit to the data. The results of this study have produced a scale of safety climate for aviation that is both reliable and valid. This study developed a tool to assess the level of perceived safety climate, specifically of pilots, but may also, with minor modifications, be used to assess other groups' perceptions of safety climate.

Modified Light Duty AM2 Capability Assessment

DTIC Science & Technology

The Modified Light -Duty AM2 matting was designed specifically for lightweight, remote-piloted aircraft (RPA) applications. An in- depth study was... Ratio (CBR) of 6. To understand the full potential of the Modified Light -Duty AM2, a full- scale evaluation was performed with contingency C-17 and...stir welding for use in fabrication of the lightweight RPA matting in conjunction with a full- scale test on the Modified Light -Duty AM2 matting system

Understanding and Controlling Sialylation in a CHO Fc-Fusion Process

PubMed Central

Lewis, Amanda M.; Croughan, William D.; Aranibar, Nelly; Lee, Alison G.; Warrack, Bethanne; Abu-Absi, Nicholas R.; Patel, Rutva; Drew, Barry; Borys, Michael C.; Reily, Michael D.; Li, Zheng Jian

2016-01-01

A Chinese hamster ovary (CHO) bioprocess, where the product is a sialylated Fc-fusion protein, was operated at pilot and manufacturing scale and significant variation of sialylation level was observed. In order to more tightly control glycosylation profiles, we sought to identify the cause of variability. Untargeted metabolomics and transcriptomics methods were applied to select samples from the large scale runs. Lower sialylation was correlated with elevated mannose levels, a shift in glucose metabolism, and increased oxidative stress response. Using a 5-L scale model operated with a reduced dissolved oxygen set point, we were able to reproduce the phenotypic profiles observed at manufacturing scale including lower sialylation, higher lactate and lower ammonia levels. Targeted transcriptomics and metabolomics confirmed that reduced oxygen levels resulted in increased mannose levels, a shift towards glycolysis, and increased oxidative stress response similar to the manufacturing scale. Finally, we propose a biological mechanism linking large scale operation and sialylation variation. Oxidative stress results from gas transfer limitations at large scale and the presence of oxygen dead-zones inducing upregulation of glycolysis and mannose biosynthesis, and downregulation of hexosamine biosynthesis and acetyl-CoA formation. The lower flux through the hexosamine pathway and reduced intracellular pools of acetyl-CoA led to reduced formation of N-acetylglucosamine and N-acetylneuraminic acid, both key building blocks of N-glycan structures. This study reports for the first time a link between oxidative stress and mammalian protein sialyation. In this study, process, analytical, metabolomic, and transcriptomic data at manufacturing, pilot, and laboratory scales were taken together to develop a systems level understanding of the process and identify oxygen limitation as the root cause of glycosylation variability. PMID:27310468

Piloted evaluation of an integrated propulsion and flight control simulator

NASA Technical Reports Server (NTRS)

Bright, Michelle M.; Simon, Donald L.

1992-01-01

A piloted evaluation of the integrated flight and propulsion control simulator for advanced integrated propulsion and airframe control design is described. The evaluation will cover control effector gains and deadbands, control effectiveness and control authority, and heads up display functionality. For this evaluation the flight simulator is configured for transition flight using an advanced Short Take-Off and Vertical Landing fighter aircraft model, a simplified high-bypass turbofan engine model, fighter cockpit displays, and pilot effectors. The piloted tasks used for rating displays and control effector gains are described. Pilot comments and simulation results confirm that the display symbology and control gains are very adequate for the transition flight task. Additionally, it is demonstrated that this small-scale, fixed base flight simulator facility can adequately perform a real time, piloted control evaluation.

Comparative effectiveness and cost-effectiveness of Chuna manual therapy versus conventional usual care for nonacute low back pain: study protocol for a pilot multicenter, pragmatic randomized controlled trial (pCRN study).

PubMed

Shin, Byung-Cheul; Kim, Me-Riong; Cho, Jae-Heung; Jung, Jae-Young; Kim, Koh-Woon; Lee, Jun-Hwan; Nam, Kibong; Lee, Min Ho; Hwang, Eui-Hyoung; Heo, Kwang-Ho; Kim, Namkwen; Ha, In-Hyuk

2017-01-17

While Chuna manual therapy is a Korean manual therapy widely used primarily for low back pain (LBP)-related disorders in Korea, well-designed studies on the comparative effectiveness of Chuna manual therapy are scarce. This study is the protocol for a three-armed, multicenter, pragmatic randomized controlled pilot trial. Sixty severe nonacute LBP patients (pain duration of at least 3 weeks, Numeric Rating Scale (NRS) ≥5) will be recruited at four Korean medicine hospitals. Participants will be randomly allocated to the Chuna group (n = 20), usual care group (n = 20), or Chuna plus usual care group (n = 20) for 6 weeks of treatment. Usual care will consist of orally administered conventional medicine, physical therapy, and back pain care education. The trial will be conducted with outcome assessor and statistician blinding. The primary endpoint will be NRS of LBP at week 7 post randomization. Secondary outcomes include NRS of leg pain, the Oswestry Disability Index (ODI), the Patient Global Impression of Change (PGIC), the Credibility and Expectancy Questionnaire, lumbar range of motion (ROM), the EuroQol-5 Dimension (EQ-5D) health survey, the Health Utility Index III (HUI-III), and economic evaluation and safety data. Post-treatment follow-ups will be conducted at 1, 4, and 10 weeks after conclusion of treatment. This study will assess the comparative effectiveness of Chuna manual therapy compared to conventional usual care. Costs and effectiveness (utility) data will be analyzed for exploratory cost-effectiveness analysis. If this pilot study does not reach a definite conclusion due to its small sample size, these results will be used as preliminary results to calculate sample size for future large-scale clinical trials and contribute in the assessment of feasibility of a full-scale multicenter trial. Clinical Research Information Service (CRIS), KCT0001850 . Registered on 17 March 2016.

Improvement of ε-poly-L-lysine production through seed stage development based on in situ pH monitoring.

PubMed

Sun, Qi-Xing; Chen, Xu-Sheng; Ren, Xi-Dong; Mao, Zhong-Gui

2015-01-01

Nissin, natamycin, and ε-poly-L-lysine (ε-PL) are three safe, microbial-produced food preservatives used today in the food industry. However, current industrial production of ε-PL is only performed in several countries. In order to realize large-scale ε-PL production by fermentation, the effects of seed stage on cell growth and ε-PL production were investigated by monitoring of pH in situ in a 5-L laboratory-scale fermenter. A significant increase in ε-PL production in fed-batch fermentation by Streptomyces sp. M-Z18 was achieved, at 48.9 g/L, through the optimization of several factors associated with seed stage, including spore pretreatment, inoculum age, and inoculum level. Compared with conventional fermentation approaches using 24-h-old shake-flask seed broth as inoculum, the maximum ε-PL concentration and productivity were enhanced by 32.3 and 36.6 %, respectively. The effect of optimized inoculum conditions on ε-PL production on a large scale was evaluated using a 50-L pilot-scale fermenter, attaining a maximum ε-PL production of 36.22 g/L in fed-batch fermentation, constituting the first report of ε-PL production at pilot scale. These results will be helpful for efficient ε-PL production by Streptomyces at pilot and plant scales.

Influence of high gas production during thermophilic anaerobic digestion in pilot-scale and lab-scale reactors on survival of the thermotolerant pathogens Clostridium perfringens and Campylobacter jejuni in piggery wastewater.

PubMed

Skillman, L C; Bajsa, O; Ho, L; Santhanam, B; Kumar, M; Ho, G

2009-07-01

Safe reuse of animal wastes to capture energy and nutrients, through anaerobic digestion processes, is becoming an increasingly desirable solution to environmental pollution. Pathogen decay is the most important safety consideration and is in general, improved at elevated temperatures and longer hydraulic residence times. During routine sampling to assess pathogen decay in thermophilic digestion, an inversely proportional relationship between levels of Clostridium perfringens and gas production was observed. Further samples were collected from pilot-scale, bench-scale thermophilic reactors and batch scale vials to assess whether gas production (predominantly methane) could be a useful indicator of decay of the thermotolerant pathogens C. perfringens and Campylobacter jejuni. Pathogen levels did appear to be lower where gas production and levels of methanogens were higher. This was evident at each operating temperature (50, 57, 65 degrees C) in the pilot-scale thermophilic digesters, although higher temperatures also reduced the numbers of pathogens detected. When methane production was higher, either when feed rate was increased, or pH was lowered from 8.2 (piggery wastewater) to 6.5, lower numbers of pathogens were detected. Although a number of related factors are known to influence the amount and rate of methane production, it may be a useful indicator of the removal of the pathogens C. perfringens and C. jejuni.

Leaching behaviour of different scrap materials at recovery and recycling companies: full-, pilot- and lab-scale investigation.

PubMed

Blondeel, E; Chys, M; Depuydt, V; Folens, K; Du Laing, G; Verliefde, A; Van Hulle, S W H

2014-12-01

Scrap material recovery and recycling companies are confronted with waste water that has a highly fluctuating flow rate and composition. Common pollutants, such as COD, nutrients and suspended solids, potentially toxic metals, polyaromatic hydrocarbons and poly chlorinated biphenyls can exceed the discharge limits. An analysis of the leaching behaviour of different scrap materials and scrap yard sweepings was performed at full-scale, pilot-scale and lab-scale in order to find possible preventive solutions for this waste water problem. The results of these leaching tests (with concentrations that frequently exceeded the Flemish discharge limits) showed the importance of regular sweeping campaigns at the company, leak proof or covered storage of specific scrap materials and oil/water separation on particular leachates. The particulate versus dissolved fraction was also studied for the pollutants. For example, up to 98% of the polyaromatic hydrocarbons, poly chlorinated biphenyls and some metals were in the particulate form. This confirms the (potential) applicability of sedimentation and filtration techniques for the treatment of the majority of the leachates, and as such the rainwater run-off as a whole. Copyright © 2014 Elsevier Ltd. All rights reserved.

Young Children's Participation and Environment Measure: Swedish Cultural Adaptation.

PubMed

Åström, Frida Marie; Khetani, Mary; Axelsson, Anna Karin

2018-08-01

To culturally adapt and evaluate the psychometric properties of the Young Children's Participation and Environment Measure (YC-PEM) for use by caregivers of Swedish children with and without disabilities, aged 2-5 years. Thirteen cognitive interviews and two focus groups with caregivers of children with and without disabilities were conducted to evaluate the cultural relevance of YC-PEM content for use in Sweden. Per participant feedback, a revised version of the Swedish YC-PEM was created and pilot tested with caregivers of children with disabilities (n = 11) and children with typical development (n = 22). User feedback informed content revisions to 7% of items. Internal consistency estimates of the Swedish YC-PEM pilot version were acceptable and ranged from .70 to .92 for all but two of the YC-PEM scales. Mean percentage agreement between raters ranged from 47% to 93% across YC-PEM scales for inter-rater, and 44% to 86% for test-retest. One of twelve YC-PEM scales revealed significant group differences between young children with and without disabilities. This study contributes preliminary evidence for the use of some scales within a culturally adapted YC-PEM in Sweden. Further validation with larger samples will allow for parametric testing to evaluate its psychometric properties.

Developing an Assessment Method of Active Aging: University of Jyvaskyla Active Aging Scale.

PubMed

Rantanen, Taina; Portegijs, Erja; Kokko, Katja; Rantakokko, Merja; Törmäkangas, Timo; Saajanaho, Milla

2018-01-01

To develop an assessment method of active aging for research on older people. A multiphase process that included drafting by an expert panel, a pilot study for item analysis and scale validity, a feedback study with focus groups and questionnaire respondents, and a test-retest study. Altogether 235 people aged 60 to 94 years provided responses and/or feedback. We developed a 17-item University of Jyvaskyla Active Aging Scale with four aspects in each item (goals, ability, opportunity, and activity; range 0-272). The psychometric and item properties are good and the scale assesses a unidimensional latent construct of active aging. Our scale assesses older people's striving for well-being through activities pertaining to their goals, abilities, and opportunities. The University of Jyvaskyla Active Aging Scale provides a quantifiable measure of active aging that may be used in postal questionnaires or interviews in research and practice.

Evaluation and Testing of IONSIV IE-911 for the Removal of Cesium-137 from INEEL Tank Waste and Dissolved Calcines

DOE Office of Scientific and Technical Information (OSTI.GOV)

N. R. Mann; T. A. Todd; K. N. Brewer

1999-04-01

Development of waste treatment processes for the remediation of radioactive wastes is currently underway. A number of experiments were performed at the Idaho Nuclear Technology and Environmental Center (INTEC) located at the Idaho National Engineering and Environmental Laboratory (INEEL) with the commercially available sorbent material, IONSIV IE-911, crystalline silicotitanate (CST), manufactured by UOP LLC. The purpose of this work was to evaluate the removal efficiency, sorbent capacity and selectivity of CST for removing Cs-137 from actual and simulated acidic tank waste in addition to dissolved pilot-plant calcine solutions. The scope of this work included batch contact tests performed with non-radioactivemore » dissolved Al and Run-64 pilot plant calcines in addition to simulants representing the average composition of tank waste. Small-scale column tests were performed with actual INEEL tank WM-183 waste, tank waste simulant, dissolved Al and Run-64 pilot plant calcine solutions. Small-scale column experiments using actual WM-183 tank waste resulted in fifty-percent Cs-137 breakthrough at approximately 589 bed volumes. Small-scale column experiments using the tank waste simulant displayed fifty-percent Cs-137 breakthrough at approximately 700 bed volumes. Small-scale column experiments using dissolved Al calcine simulant displayed fifty-percent Cs-137 breakthrough at approximately 795 bed volumes. Column experiments with dissolved Run-64, pilot plant calcine did not reach fifty-percent breakthrough throughout the test.« less

Development of the Military Women's Attitudes Toward Menstrual Suppression Scale: from construct definition to pilot testing.

PubMed

Trego, Lori L

2009-01-01

The Military Women's Attitudes Toward Menstrual Suppression scale (MWATMS) was created to measure attitudes toward menstrual suppression during deployment. The human health and social ecology theories were integrated to conceptualize an instrument that accounts for military-unique aspects of the environment on attitudes toward suppression. A three-step instrument development process was followed to develop the MWATMS. The instrument was pilot tested on a convenience sample of 206 military women with deployment experience. Reliability was tested with measures of internal consistency (alpha = .97); validity was tested with principal components analysis with varimax rotation. Four components accounted for 65% of variance: Benefits/Interest, Hygiene, Convenience, and Soldier/Stress. The pilot test of the MWATMS supported its reliability and validity. Further testing is warranted for validation of this instrument.

Effect of Atomoxetine on the Cognitive Functions in Treatment of Attention Deficit Hyperactivity Disorder in Children with Congenital Hypothyroidism: A Pilot Study.

PubMed

Yang, Rongwang; Gao, Weijia; Li, Rong; Zhao, Zhengyan

2015-04-19

With early initiation of thyroxine supplementation, children with congenital hypothyroidism (CH) retain some subtle deficits, such as attention and inhibitory control problems. This study assessed the effects of atomoxetine on cognitive functions in treatment of attention deficit hyperactivity disorder (ADHD) symptoms in children with CH. In a 6-month, open-labeled pilot study, 12 children were recruited and received atomoxetine. The measures of efficacy were scores on the Swanson, Nolan and Pelham Teacher and Parent Rating Scale, version IV (SNAP-IV) and Clinical Global Impression-Severity scale (CGI-S). The cognitive functions were evaluated with the Wechsler Intelligence Scale for Chinese Children, Digit Span, Wisconsin Card Sorting Test, and Stroop test. A statistically significant difference was found between the mean CGI-S and SNAP-IV scores before and after treatment (p < 0.01). All the indicators of cognitive functions at the endpoint were improved compared with those at baseline. No serious adverse events were reported. Atomoxetine appears to be useful in improving ADHD symptoms, as well as cognitive functions, in children with CH. Larger, randomized, double-blinded, clinical trials are required to replicate these results. © The Author 2015. Published by Oxford University Press on behalf of CINP.

Effect of a steam foot spa on geriatric inpatients with cognitive impairment: a pilot study

PubMed Central

Koike, Yoshihisa; Kondo, Hideki; Kondo, Satoshi; Takagi, Masayuki; Kano, Yoshio

2013-01-01

Purpose To investigate whether a steam foot spa improves cognitive impairment in geriatric inpatients. Methods Geriatric inpatients with cognitive impairment were given a steam foot spa treatment at 42°C for 20 minutes for 2 weeks (5 days/week). Physiological indicators such as blood pressure, percutaneous oxygen saturation, pulse, tympanic temperature, and sleep time and efficiency were assessed. Cognitive function and behavioral and psychological symptoms of dementia were assessed using the Mini-Mental State Examination, Dementia Mood Assessment Scale, and Dementia Behavior Disturbance scale. Results Significant decreases in systolic (P < 0.01) and diastolic blood pressure (P < 0.05) along with a significant increase in tympanic temperature (P < 0.01) were observed after the steam foot spas. A significant improvement was seen in the Mini-Mental State Examination score (P < 0.01) and the overall dementia severity items in Dementia Mood Assessment Scale (P < 0.05). Limitations Japanese people are very fond of foot baths. However, it is difficult to understand why inpatients cannot receive steam foot baths. In this study, a control group was not used. Raters and enforcers were not blinded. Conclusion The results of this pilot study suggest that steam foot spas mitigate cognitive impairment in geriatric inpatients. PMID:23717038

The Development and Piloting of Parallel Scales Measuring External and Internal HIV and Tuberculosis Stigma Among Healthcare Workers in the Free State Province, South Africa.

PubMed

Wouters, Edwin; Rau, Asta; Engelbrecht, Michelle; Uebel, Kerry; Siegel, Jacob; Masquillier, Caroline; Kigozi, Gladys; Sommerland, Nina; Yassi, Annalee

2016-05-15

The dual burden of tuberculosis and human immunodeficiency virus (HIV) is severely impacting the South African healthcare workforce. However, the use of on-site occupational health services is hampered by stigma among the healthcare workforce. The success of stigma-reduction interventions is difficult to evaluate because of a dearth of appropriate scientific tools to measure stigma in this specific professional setting. The current pilot study aimed to develop and test a range of scales measuring different aspects of stigma-internal and external stigma toward tuberculosis as well as HIV-in a South African healthcare setting. The study employed data of a sample of 200 staff members of a large hospital in Bloemfontein, South Africa. Confirmatory factor analysis produced 7 scales, displaying internal construct validity: (1) colleagues' external HIV stigma, (2) colleagues' actions against external HIV stigma, (3) respondent's external HIV stigma, (4) respondent's internal HIV stigma, (5) colleagues' external tuberculosis stigma, (6) respondent's external tuberculosis stigma, and (7) respondent's internal tuberculosis stigma. Subsequent analyses (reliability analysis, structural equation modeling) demonstrated that the scales displayed good psychometric properties in terms of reliability and external construct validity. The study outcomes support the use of the developed scales as a valid and reliable means to measure levels of tuberculosis- and HIV-related stigma among the healthcare workforce in a resource-limited context. Future studies should build on these findings to fine-tune the instruments and apply them to larger study populations across a range of different resource-limited healthcare settings with high HIV and tuberculosis prevalence. © The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail journals.permissions@oup.com.

The Development and Piloting of Parallel Scales Measuring External and Internal HIV and Tuberculosis Stigma Among Healthcare Workers in the Free State Province, South Africa

PubMed Central

Wouters, Edwin; Rau, Asta; Engelbrecht, Michelle; Uebel, Kerry; Siegel, Jacob; Masquillier, Caroline; Kigozi, Gladys; Sommerland, Nina; Yassi, Annalee

2016-01-01

Background The dual burden of tuberculosis and human immunodeficiency virus (HIV) is severely impacting the South African healthcare workforce. However, the use of on-site occupational health services is hampered by stigma among the healthcare workforce. The success of stigma-reduction interventions is difficult to evaluate because of a dearth of appropriate scientific tools to measure stigma in this specific professional setting. Methods The current pilot study aimed to develop and test a range of scales measuring different aspects of stigma—internal and external stigma toward tuberculosis as well as HIV—in a South African healthcare setting. The study employed data of a sample of 200 staff members of a large hospital in Bloemfontein, South Africa. Results Confirmatory factor analysis produced 7 scales, displaying internal construct validity: (1) colleagues’ external HIV stigma, (2) colleagues’ actions against external HIV stigma, (3) respondent’s external HIV stigma, (4) respondent’s internal HIV stigma, (5) colleagues’ external tuberculosis stigma, (6) respondent’s external tuberculosis stigma, and (7) respondent’s internal tuberculosis stigma. Subsequent analyses (reliability analysis, structural equation modeling) demonstrated that the scales displayed good psychometric properties in terms of reliability and external construct validity. Conclusions The study outcomes support the use of the developed scales as a valid and reliable means to measure levels of tuberculosis- and HIV-related stigma among the healthcare workforce in a resource-limited context. Future studies should build on these findings to fine-tune the instruments and apply them to larger study populations across a range of different resource-limited healthcare settings with high HIV and tuberculosis prevalence. PMID:27118854

Recruitment and accrual of women in a placebo-controlled clinical pilot study on manual therapy.

PubMed

Cambron, Jerrilyn A; Hawk, Cheryl; Evans, Roni; Long, Cynthia R

2004-06-01

To investigate the accrual rates and recruitment processes among 3 Midwestern sites during a pilot study on manual therapy for chronic pelvic pain. Multisite pilot study for a randomized, placebo-controlled clinical trial. Three chiropractic institutions in or near major metropolitan cities in the Midwestern United States. Thirty-nine women aged 18 to 45 with chronic pelvic pain of at least 6 months duration, diagnosed by a board certified gynecologist. The method of recruitment was collected for each individual who responded to an advertisement and completed an interviewer-administered telephone screen. Participants who were willing and eligible after 3 baseline visits were entered into a randomized clinical trial. The number of responses and accrual rates were determined for the overall study, each of the 3 treatment sites, and each of the 5 recruitment efforts. In this study, 355 women were screened over the telephone and 39 were randomized, making the rate of randomization approximately 10%. The most effective recruitment methods leading to randomization were direct mail (38%) and radio advertisements (34%). However, success of the recruitment process differed by site. Based on the accrual of this multisite pilot study, a full-scale trial would not be feasible using this study's parameters. However, useful information was gained on recruitment effectiveness, eligibility criteria, and screening protocols among the 3 metropolitan sites.

PILOT PLANT TESTING OF ELEMENTAL MERCURY RE-EMISSION FROM WET SCRUBBERS

EPA Science Inventory

A pilot-scale wet lime/limestone flue gas desulfurization scrubber system was designed to conduct mercury emission control research. The first tests focused on investigating the phenomenon of Hgo re-emission from wet scrubbers with a specific objective of developing a Hgo re-emis...

Interpreted Cooper-Harper for broader use

NASA Technical Reports Server (NTRS)

Green, David L.; Andrews, Hal; Gallagher, Donald W.

1993-01-01

The current aircraft assessment process typically makes extensive use of operational personnel during simulations and operational evaluations, with increased emphasis on evaluating the many pilot and/or operator/aircraft control loops. The need for a crew assessment in this broader arena has produced a variety of rating scales. The Cooper-Harper Rating Scale is frequently misused and routinely overlooked in the process, for these applications often extend the scale's use beyond its originally intended application. This paper agrees with the broader application of the Cooper-Harper Rating Scale and presents a concept for the development of a 'use unique' Interpreted Cooper-Harper Scale to help achieve this objective. This interpreted scale concept was conceived during efforts to support an FAA evaluation of a night vision enhancement system. It includes descriptive extensions, which are faithful to the intent of the current Cooper-Harper Scale and should provide the kind of detail that has historically been provided by trained test pilots in their explanatory comments.