Electrical description of N2 capacitively coupled plasmas with the global model

NASA Astrophysics Data System (ADS)

Cao, Ming-Lu; Lu, Yi-Jia; Cheng, Jia; Ji, Lin-Hong; Engineering Design Team

2016-10-01

N2 discharges in a commercial capacitively coupled plasma reactor are modelled by a combination of an equivalent circuit and the global model, for a range of gas pressure at 1 4 Torr. The ohmic and inductive plasma bulk and the capacitive sheath are represented as LCR elements, with electrical characteristics determined by plasma parameters. The electron density and electron temperature are obtained from the global model in which a Maxwellian electron distribution is assumed. Voltages and currents are recorded by a VI probe installed after the match network. Using the measured voltage as an input, the current flowing through the discharge volume is calculated from the electrical model and shows excellent agreement with the measurements. The experimentally verified electrical model provides a simple and accurate description for the relationship between the external electrical parameters and the plasma properties, which can serve as a guideline for process window planning in industrial applications.

Multiple-Input Subject-Specific Modeling of Plasma Glucose Concentration for Feedforward Control.

PubMed

Kotz, Kaylee; Cinar, Ali; Mei, Yong; Roggendorf, Amy; Littlejohn, Elizabeth; Quinn, Laurie; Rollins, Derrick K

2014-11-26

The ability to accurately develop subject-specific, input causation models, for blood glucose concentration (BGC) for large input sets can have a significant impact on tightening control for insulin dependent diabetes. More specifically, for Type 1 diabetics (T1Ds), it can lead to an effective artificial pancreas (i.e., an automatic control system that delivers exogenous insulin) under extreme changes in critical disturbances. These disturbances include food consumption, activity variations, and physiological stress changes. Thus, this paper presents a free-living, outpatient, multiple-input, modeling method for BGC with strong causation attributes that is stable and guards against overfitting to provide an effective modeling approach for feedforward control (FFC). This approach is a Wiener block-oriented methodology, which has unique attributes for meeting critical requirements for effective, long-term, FFC.

Baffle aperture design study of hollow cathode equipped ion thrusters. M.S. Thesis Technical Report, 1 Dec. 1979 - 1 Oct. 1980

NASA Technical Reports Server (NTRS)

Brophy, J. R., Jr.; Wilbur, P. J.

1980-01-01

A simple theoretical model which can be used as an aid in the design of the baffle aperture region of a hollow cathode equipped ion thruster was developed. An analysis of the ion and electron currents in both the main and cathode discharge chambers is presented. From this analysis a model of current flow through the aperture, which is required as an input to the design model, was developed. This model was verified experimentally. The dominant force driving electrons through the aperture was the force due to the electrical potential gradient. The diffusion process was modeled according to the Bolm diffusion theory. A number of simplifications were made to limit the amount of detailed plasma information required as input to the model to facilitate the use of the model in thruster design. This simplified model gave remarkably consistant results with experimental results obtained with a given thruster geometry over substantial changes in operating conditions. The model was uncertain to about a factor of two for different thruster cathode region geometries. The design usefulness was limited by this factor of two uncertainty and by the accuracy to which the plasma parameters required as inputs to the model were specified.

A Numerical Characterization of the Gravito-Electrostatic Sheath Equilibrium Structure in Solar Plasma

NASA Astrophysics Data System (ADS)

Karmakar, Pralay Kumar

This article describes the equilibrium structure of the solar interior plasma (SIP) and solar wind plasma (SWP) in detail under the framework of the gravito-electrostatic sheath (GES) model. This model gives a precise definition of the solar surface boundary (SSB), surface origin mechanism of the subsonic SWP, and its supersonic acceleration. Equilibrium parameters like plasma potential, self-gravity, population density, flow, their gradients, and all the relevant inhomogeneity scale lengths are numerically calculated and analyzed as an initial value problem. Physical significance of the structure condition for the SSB is discussed. The plasma oscillation and Jeans time scales are also plotted and compared. In addition, different coupling parameters, and electric current profiles are also numerically studied. The current profiles exhibit an important behavior of directional reversibility, i.e., an electrodynamical transition from negative to positive value. It occurs beyond a few Jeans lengths away from the SSB. The virtual spherical surface lying at the current reversal point, where the net current becomes zero, has the property of a floating surface behavior of the real physical wall. Our investigation indicates that the SWP behaves as an ion current-carrying plasma system. The basic mechanism behind the GES formation and its distinctions from conventional plasma sheath are discussed. The electromagnetic properties of the Sun derived from our model with the most accurate available inputs are compared with those of others. These results are useful as an input element to study the properties of the linear and nonlinear dynamics of various solar plasma waves, oscillations and instabilities.

Real-time plasma control in a dual-frequency, confined plasma etcher

NASA Astrophysics Data System (ADS)

Milosavljević, V.; Ellingboe, A. R.; Gaman, C.; Ringwood, J. V.

2008-04-01

The physics issues of developing model-based control of plasma etching are presented. A novel methodology for incorporating real-time model-based control of plasma processing systems is developed. The methodology is developed for control of two dependent variables (ion flux and chemical densities) by two independent controls (27 MHz power and O2 flow). A phenomenological physics model of the nonlinear coupling between the independent controls and the dependent variables of the plasma is presented. By using a design of experiment, the functional dependencies of the response surface are determined. In conjunction with the physical model, the dependencies are used to deconvolve the sensor signals onto the control inputs, allowing compensation of the interaction between control paths. The compensated sensor signals and compensated set-points are then used as inputs to proportional-integral-derivative controllers to adjust radio frequency power and oxygen flow to yield the desired ion flux and chemical density. To illustrate the methodology, model-based real-time control is realized in a commercial semiconductor dielectric etch chamber. The two radio frequency symmetric diode operates with typical commercial fluorocarbon feed-gas mixtures (Ar/O2/C4F8). Key parameters for dielectric etching are known to include ion flux to the surface and surface flux of oxygen containing species. Control is demonstrated using diagnostics of electrode-surface ion current, and chemical densities of O, O2, and CO measured by optical emission spectrometry and/or mass spectrometry. Using our model-based real-time control, the set-point tracking accuracy to changes in chemical species density and ion flux is enhanced.

Modeling polyvinyl chloride Plasma Modification by Neural Networks

NASA Astrophysics Data System (ADS)

Wang, Changquan

2018-03-01

Neural networks model were constructed to analyze the connection between dielectric barrier discharge parameters and surface properties of material. The experiment data were generated from polyvinyl chloride plasma modification by using uniform design. Discharge voltage, discharge gas gap and treatment time were as neural network input layer parameters. The measured values of contact angle were as the output layer parameters. A nonlinear mathematical model of the surface modification for polyvinyl chloride was developed based upon the neural networks. The optimum model parameters were obtained by the simulation evaluation and error analysis. The results of the optimal model show that the predicted value is very close to the actual test value. The prediction model obtained here are useful for discharge plasma surface modification analysis.

Workshop on Models for Plasma Spectroscopy

NASA Astrophysics Data System (ADS)

1993-09-01

A meeting was held at St. Johns College, Oxford from Monday 27th to Thursday 30th of September 1993 to bring together a group of physicists working on computational modelling of plasma spectroscopy. The group came from the UK, France, Israel and the USA. The meeting was organized by myself, Dr. Steven Rose of RAL and Dr. R.W. Lee of LLNL. It was funded by the U.S. European Office of Aerospace Research and Development and by LLNL. The meeting grew out of a wish by a group of core participants to make available to practicing plasma physicists (particularly those engaged in the design and analysis of experiments) sophisticated numerical models of plasma physics. Additional plasma physicists attended the meeting in Oxford by invitation. These were experimentalists and users of plasma physics simulation codes whose input to the meeting was to advise the core group as to what was really needed.

DREAM-3D and the importance of model inputs and boundary conditions

NASA Astrophysics Data System (ADS)

Friedel, Reiner; Tu, Weichao; Cunningham, Gregory; Jorgensen, Anders; Chen, Yue

2015-04-01

Recent work on radiation belt 3D diffusion codes such as the Los Alamos "DREAM-3D" code have demonstrated the ability of such codes to reproduce realistic magnetospheric storm events in the relativistic electron dynamics - as long as sufficient "event-oriented" boundary conditions and code inputs such as wave powers, low energy boundary conditions, background plasma densities, and last closed drift shell (outer boundary) are available. In this talk we will argue that the main limiting factor in our modeling ability is no longer our inability to represent key physical processes that govern the dynamics of the radiation belts (radial, pitch angle and energy diffusion) but rather our limitations in specifying accurate boundary conditions and code inputs. We use here DREAM-3D runs to show the sensitivity of the modeled outcomes to these boundary conditions and inputs, and also discuss alternate "proxy" approaches to obtain the required inputs from other (ground-based) sources.

Real time closed loop control of an Ar and Ar/O2 plasma in an ICP

NASA Astrophysics Data System (ADS)

Faulkner, R.; Soberón, F.; McCarter, A.; Gahan, D.; Karkari, S.; Milosavljevic, V.; Hayden, C.; Islyaikin, A.; Law, V. J.; Hopkins, M. B.; Keville, B.; Iordanov, P.; Doherty, S.; Ringwood, J. V.

2006-10-01

Real time closed loop control for plasma assisted semiconductor manufacturing has been the subject of academic research for over a decade. However, due to process complexity and the lack of suitable real time metrology, progress has been elusive and genuine real time, multi-input, multi-output (MIMO) control of a plasma assisted process has yet to be successfully implemented in an industrial setting. A Splasma parameter control strategy T is required to be adopted whereby process recipes which are defined in terms of plasma properties such as critical species densities as opposed to input variables such as rf power and gas flow rates may be transferable between different chamber types. While PIC simulations and multidimensional fluid models have contributed considerably to the basic understanding of plasmas and the design of process equipment, such models require a large amount of processing time and are hence unsuitable for testing control algorithms. In contrast, linear dynamical empirical models, obtained through system identification techniques are ideal in some respects for control design since their computational requirements are comparatively small and their structure facilitates the application of classical control design techniques. However, such models provide little process insight and are specific to an operating point of a particular machine. An ideal first principles-based, control-oriented model would exhibit the simplicity and computational requirements of an empirical model and, in addition, despite sacrificing first principles detail, capture enough of the essential physics and chemistry of the process in order to provide reasonably accurate qualitative predictions. This paper will discuss the development of such a first-principles based, control-oriented model of a laboratory inductively coupled plasma chamber. The model consists of a global model of the chemical kinetics coupled to an analytical model of power deposition. Dynamics of actuators including mass flow controllers and exhaust throttle are included and sensor characteristics are also modelled. The application of this control-oriented model to achieve multivariable closed loop control of specific species e.g. atomic Oxygen and ion density using the actuators rf power, Oxygen and Argon flow rates, and pressure/exhaust flow rate in an Ar/O2 ICP plasma will be presented.

Uncertainty propagation by using spectral methods: A practical application to a two-dimensional turbulence fluid model

NASA Astrophysics Data System (ADS)

Riva, Fabio; Milanese, Lucio; Ricci, Paolo

2017-10-01

To reduce the computational cost of the uncertainty propagation analysis, which is used to study the impact of input parameter variations on the results of a simulation, a general and simple to apply methodology based on decomposing the solution to the model equations in terms of Chebyshev polynomials is discussed. This methodology, based on the work by Scheffel [Am. J. Comput. Math. 2, 173-193 (2012)], approximates the model equation solution with a semi-analytic expression that depends explicitly on time, spatial coordinates, and input parameters. By employing a weighted residual method, a set of nonlinear algebraic equations for the coefficients appearing in the Chebyshev decomposition is then obtained. The methodology is applied to a two-dimensional Braginskii model used to simulate plasma turbulence in basic plasma physics experiments and in the scrape-off layer of tokamaks, in order to study the impact on the simulation results of the input parameter that describes the parallel losses. The uncertainty that characterizes the time-averaged density gradient lengths, time-averaged densities, and fluctuation density level are evaluated. A reasonable estimate of the uncertainty of these distributions can be obtained with a single reduced-cost simulation.

Sequential modelling of ICRF wave near RF fields and asymptotic RF sheaths description for AUG ICRF antennas

NASA Astrophysics Data System (ADS)

Jacquot, Jonathan; Tierens, Wouter; Zhang, Wei; Bobkov, Volodymyr; Colas, Laurent; Noterdaeme, Jean-Marie

2017-10-01

A sequence of simulations is performed with RAPLICASOL and SSWICH to compare two AUG ICRF antennas. RAPLICASOL outputs have been used as input to SSWICH-SW for the AUG ICRF antennas. Using parallel electric field maps and the scattering matrix produced by RAPLICASOL, SSWICH-SW, reduced to its asymptotic part, is able to produce a 2D radial/poloidal map of the DC plasma potential accounting for the antenna input settings (total power, power balance, phasing). Two models of antennas are compared: 2-strap antenna vs 3-strap antenna. The 2D DC potential structures are correlated to structures of the parallel electric field map for different phasing and power balance. The overall DC plasma potential on the 3-strap antenna is lower due to better global RF currents compensation. Spatial proximity between regions of high RF electric field and regions where high DC plasma potentials are observed is an important factor for sheath rectification.

Radiation characteristics of input power from surface wave sustained plasma antenna

DOE Office of Scientific and Technical Information (OSTI.GOV)

Naito, T., E-mail: Naito.Teruki@bc.MitsubishiElectric.co.jp; Yamaura, S.; Fukuma, Y.

This paper reports radiation characteristics of input power from a surface wave sustained plasma antenna investigated theoretically and experimentally, especially focusing on the power consumption balance between the plasma generation and the radiation. The plasma antenna is a dielectric tube filled with argon and small amount of mercury, and the structure is a basic quarter wavelength monopole antenna at 2.45 GHz. Microwave power at 2.45 GHz is supplied to the plasma antenna. The input power is partially consumed to sustain the plasma, and the remaining part is radiated as a signal. The relationship between the antenna gain and the input powermore » is obtained by an analytical derivation and numerical simulations. As a result, the antenna gain is kept at low values, and most of the input power is consumed to increase the plasma volume until the tube is filled with the plasma whose electron density is higher than the critical electron density required for sustaining the surface wave. On the other hand, the input power is consumed to increase the electron density after the tube is fully filled with the plasma, and the antenna gain increases with increasing the electron density. The dependence of the antenna gain on the electron density is the same as that of a plasma antenna sustained by a DC glow discharge. These results are confirmed by experimental results of the antenna gain and radiation patterns. The antenna gain of the plasma is a few dB smaller than that of the identical metal antenna. The antenna gain of the plasma antenna is sufficient for the wireless communication, although it is difficult to substitute the plasma antenna for metal antennas completely. The plasma antenna is suitable for applications having high affinity with the plasma characteristics such as low interference and dynamic controllability.« less

Power accounting of plasma discharges in the linear device Proto-MPEX

NASA Astrophysics Data System (ADS)

Showers, M.; Piotrowicz, P. A.; Beers, C. J.; Biewer, T. M.; Caneses, J.; Canik, J.; Caughman, J. B. O.; Donovan, D. C.; Goulding, R. H.; Lumsdaine, A.; Kafle, N.; Owen, L. W.; Rapp, J.; Ray, H.

2018-06-01

Plasma material interaction (PMI) studies are crucial to the successful development of future fusion reactors. Prototype Material Plasma Exposure eXperiment (Proto-MPEX) is a prototype design for the MPEX, a steady-state linear device being developed to study PMI. The primary purpose of Proto-MPEX is developing the plasma heating source concepts for MPEX. A power accounting study of Proto-MPEX works to identify machine operating parameters that could improve its performance, thereby increasing its PMI research capabilities, potentially impacting the MPEX design concept. To build a comprehensive power balance, an analysis of the helicon region has been performed implementing a diagnostic suite and software modeling to identify mechanisms and locations of heat loss from the main plasma. Of the 106.3 kW of input power, up to 90.5% of the power has been accounted for in the helicon region. When the analysis was extended to encompass the device to its end plates, 49.2% of the input power was accounted for and verified diagnostically. Areas requiring further diagnostic analysis are identified. The required improvements will be implemented in future work. The data acquisition and analysis processes will be streamlined to form a working model for future power balance studies of Proto-MPEX. ).

Interpreting Disruption Prediction Models to Improve Plasma Control

NASA Astrophysics Data System (ADS)

Parsons, Matthew

2017-10-01

In order for the tokamak to be a feasible design for a fusion reactor, it is necessary to minimize damage to the machine caused by plasma disruptions. Accurately predicting disruptions is a critical capability for triggering any mitigative actions, and a modest amount of attention has been given to efforts that employ machine learning techniques to make these predictions. By monitoring diagnostic signals during a discharge, such predictive models look for signs that the plasma is about to disrupt. Typically these predictive models are interpreted simply to give a `yes' or `no' response as to whether a disruption is approaching. However, it is possible to extract further information from these models to indicate which input signals are more strongly correlated with the plasma approaching a disruption. If highly accurate predictive models can be developed, this information could be used in plasma control schemes to make better decisions about disruption avoidance. This work was supported by a Grant from the 2016-2017 Fulbright U.S. Student Program, administered by the Franco-American Fulbright Commission in France.

Validation and quantification of [18F]altanserin binding in the rat brain using blood input and reference tissue modeling

PubMed Central

Riss, Patrick J; Hong, Young T; Williamson, David; Caprioli, Daniele; Sitnikov, Sergey; Ferrari, Valentina; Sawiak, Steve J; Baron, Jean-Claude; Dalley, Jeffrey W; Fryer, Tim D; Aigbirhio, Franklin I

2011-01-01

The 5-hydroxytryptamine type 2a (5-HT2A) selective radiotracer [18F]altanserin has been subjected to a quantitative micro-positron emission tomography study in Lister Hooded rats. Metabolite-corrected plasma input modeling was compared with reference tissue modeling using the cerebellum as reference tissue. [18F]altanserin showed sufficient brain uptake in a distribution pattern consistent with the known distribution of 5-HT2A receptors. Full binding saturation and displacement was documented, and no significant uptake of radioactive metabolites was detected in the brain. Blood input as well as reference tissue models were equally appropriate to describe the radiotracer kinetics. [18F]altanserin is suitable for quantification of 5-HT2A receptor availability in rats. PMID:21750562

High Power Light Gas Helicon Plasma Source For VASMIR

NASA Technical Reports Server (NTRS)

Squire, J. P.; Chang-Diaz, F. R.; Glover, T. W.; Jacobson, V. T.; McCaskill, G. E.; Winter, D. S.; Baity, F. W.; Carter, M. D.; Goulding, R. H.

2004-01-01

The VASIMR space propulsion development effort relies on a high power (greater than 10kW) helicon source to produce a dense flowing plasma (H, D and He) target for ion cyclotron resonance (ICR) acceleration of the ions. Subsequent expansion in an expanding magnetic field (magnetic nozzle) converts ion lunetic energy to directed momentum. This plasma source must have critical features to enable an effective propulsion device. First, it must ionize most of the input neutral flux of gas, thus producing a plasma stream with a high degree of ionization for application of ICR power. This avoids propellant waste and potential power losses due to charge exchange. Next, the plasma stream must flow into a region of high magnetic field (approximately 0.5 T) for efficient ICR acceleration. Third, the ratio of input power to plasma flux must be low, providing an energy per ion-electron pair approaching 100 eV. Lastly, the source must be robust and capable of very long life-times (years). In our helicon experiment (VX-10) we have measured a ratio of input gas to plasma flux near 100%. The plasma flows from the helicon region (B approximately 0.1 T) into a region with a peak magnetic field of 0.8 T. The energy input per ion-electron pair has been measured at 300 plus or minus 100 eV. Recent results at Oak Ridge National Laboratory (ORNL) show an enhanced efficiency mode of operation with a high power density, over 5 kW in a 5 cm diameter tube. Our helicon is presently 9 cm in diameter and operates up to 3.5 kW of input power. An upgrade to a power level of 10 kW is underway. Much of our recent work has been with a Boswell double-saddle antenna design. We are also converting the antenna design to a helical type. With these modifications, we anticipate an improvement in the ionization efficiency. This paper presents the results from scaling the helicon in the VX-10 device from 3.5 to 10 kW. We also compare the operation with a double-saddle to a helical antenna design. Finally, we discuss modeling of these configurations using ORNL's EMIR code.

Large-Area Permanent-Magnet ECR Plasma Source

NASA Technical Reports Server (NTRS)

Foster, John E.

2007-01-01

A 40-cm-diameter plasma device has been developed as a source of ions for material-processing and ion-thruster applications. Like the device described in the immediately preceding article, this device utilizes electron cyclotron resonance (ECR) excited by microwave power in a magnetic field to generate a plasma in an electrodeless (noncontact) manner and without need for an electrically insulating, microwave-transmissive window at the source. Hence, this device offers the same advantages of electrodeless, windowless design - low contamination and long operational life. The device generates a uniform, high-density plasma capable of sustaining uniform ion-current densities at its exit plane while operating at low pressure [<10(exp -4) torr (less than about 1.3 10(exp -2) Pa)] and input power <200 W at a frequency of 2.45 GHz. Though the prototype model operates at 2.45 GHz, operation at higher frequencies can be achieved by straightforward modification to the input microwave waveguide. Higher frequency operation may be desirable in those applications that require even higher background plasma densities. In the design of this ECR plasma source, there are no cumbersome, power-hungry electromagnets. The magnetic field in this device is generated by a permanent-magnet circuit that is optimized to generate resonance surfaces. The microwave power is injected on the centerline of the device. The resulting discharge plasma jumps into a "high mode" when the input power rises above 150 W. This mode is associated with elevated plasma density and high uniformity. The large area and uniformity of the plasma and the low operating pressure are well suited for such material-processing applications as etching and deposition on large silicon wafers. The high exit-plane ion-current density makes it possible to attain a high rate of etching or deposition. The plasma potential is <3 V low enough that there is little likelihood of sputtering, which, in plasma processing, is undesired because it is associated with erosion and contamination. The electron temperature is low and does not vary appreciably with power.

Consistent kinetic simulation of plasma and sputtering in low temperature plasmas

NASA Astrophysics Data System (ADS)

Schmidt, Frederik; Trieschmann, Jan; Mussenbrock, Thomas

2016-09-01

Plasmas are commonly used in sputtering applications for the deposition of thin films. Although magnetron sources are a prominent choice, capacitively coupled plasmas have certain advantages (e.g., sputtering of non-conducting and/or ferromagnetic materials, aside of excellent control of the ion energy distribution). In order to understand the collective plasma and sputtering dynamics, a kinetic simulation model is helpful. Particle-in-Cell has been proven to be successful in simulating the plasma dynamics, while the Test-Multi-Particle-Method can be used to describe the sputtered neutral species. In this talk a consistent combination of these methods is presented by consistently coupling the simulated ion flux as input to a neutral particle transport model. The combined model is used to simulate and discuss the spatially dependent densities, fluxes and velocity distributions of all particles. This work is supported by the German Research Foundation (DFG) in the frame of Transregional Collaborative Research Center (SFB) TR-87.

Orchestrating TRANSP Simulations for Interpretative and Predictive Tokamak Modeling with OMFIT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grierson, B. A.; Yuan, X.; Gorelenkova, M.

TRANSP simulations are being used in the OMFIT work- flow manager to enable a machine independent means of experimental analysis, postdictive validation, and predictive time dependent simulations on the DIII-D, NSTX, JET and C-MOD tokamaks. The procedures for preparing the input data from plasma profile diagnostics and equilibrium reconstruction, as well as processing of the time-dependent heating and current drive sources and assumptions about the neutral recycling, vary across machines, but are streamlined by using a common workflow manager. Settings for TRANSP simulation fidelity are incorporated into the OMFIT framework, contrasting between-shot analysis, power balance, and fast-particle simulations. A previouslymore » established series of data consistency metrics are computed such as comparison of experimental vs. calculated neutron rate, equilibrium stored energy vs. total stored energy from profile and fast-ion pressure, and experimental vs. computed surface loop voltage. Discrepancies between data consistency metrics can indicate errors in input quantities such as electron density profile or Zeff, or indicate anomalous fast-particle transport. Measures to assess the sensitivity of the verification metrics to input quantities are provided by OMFIT, including scans of the input profiles and standardized post-processing visualizations. For predictive simulations, TRANSP uses GLF23 or TGLF to predict core plasma profiles, with user defined boundary conditions in the outer region of the plasma. ITPA validation metrics are provided in post-processing to assess the transport model validity. By using OMFIT to orchestrate the steps for experimental data preparation, selection of operating mode, submission, post-processing and visualization, we have streamlined and standardized the usage of TRANSP.« less

Orchestrating TRANSP Simulations for Interpretative and Predictive Tokamak Modeling with OMFIT

DOE PAGES

Grierson, B. A.; Yuan, X.; Gorelenkova, M.; ...

2018-02-21

TRANSP simulations are being used in the OMFIT work- flow manager to enable a machine independent means of experimental analysis, postdictive validation, and predictive time dependent simulations on the DIII-D, NSTX, JET and C-MOD tokamaks. The procedures for preparing the input data from plasma profile diagnostics and equilibrium reconstruction, as well as processing of the time-dependent heating and current drive sources and assumptions about the neutral recycling, vary across machines, but are streamlined by using a common workflow manager. Settings for TRANSP simulation fidelity are incorporated into the OMFIT framework, contrasting between-shot analysis, power balance, and fast-particle simulations. A previouslymore » established series of data consistency metrics are computed such as comparison of experimental vs. calculated neutron rate, equilibrium stored energy vs. total stored energy from profile and fast-ion pressure, and experimental vs. computed surface loop voltage. Discrepancies between data consistency metrics can indicate errors in input quantities such as electron density profile or Zeff, or indicate anomalous fast-particle transport. Measures to assess the sensitivity of the verification metrics to input quantities are provided by OMFIT, including scans of the input profiles and standardized post-processing visualizations. For predictive simulations, TRANSP uses GLF23 or TGLF to predict core plasma profiles, with user defined boundary conditions in the outer region of the plasma. ITPA validation metrics are provided in post-processing to assess the transport model validity. By using OMFIT to orchestrate the steps for experimental data preparation, selection of operating mode, submission, post-processing and visualization, we have streamlined and standardized the usage of TRANSP.« less

Integration of RAM-SCB into the Space Weather Modeling Framework

DOE PAGES

Welling, Daniel; Toth, Gabor; Jordanova, Vania Koleva; ...

2018-02-07

We present that numerical simulations of the ring current are a challenging endeavor. They require a large set of inputs, including electric and magnetic fields and plasma sheet fluxes. Because the ring current broadly affects the magnetosphere-ionosphere system, the input set is dependent on the ring current region itself. This makes obtaining a set of inputs that are self-consistent with the ring current difficult. To overcome this challenge, researchers have begun coupling ring current models to global models of the magnetosphere-ionosphere system. This paper describes the coupling between the Ring current Atmosphere interaction Model with Self-Consistent Magnetic field (RAM-SCB) tomore » the models within the Space Weather Modeling Framework. Full details on both previously introduced and new coupling mechanisms are defined. Finally, the impact of self-consistently including the ring current on the magnetosphere-ionosphere system is illustrated via a set of example simulations.« less

Integration of RAM-SCB into the Space Weather Modeling Framework

DOE Office of Scientific and Technical Information (OSTI.GOV)

Welling, Daniel; Toth, Gabor; Jordanova, Vania Koleva

We present that numerical simulations of the ring current are a challenging endeavor. They require a large set of inputs, including electric and magnetic fields and plasma sheet fluxes. Because the ring current broadly affects the magnetosphere-ionosphere system, the input set is dependent on the ring current region itself. This makes obtaining a set of inputs that are self-consistent with the ring current difficult. To overcome this challenge, researchers have begun coupling ring current models to global models of the magnetosphere-ionosphere system. This paper describes the coupling between the Ring current Atmosphere interaction Model with Self-Consistent Magnetic field (RAM-SCB) tomore » the models within the Space Weather Modeling Framework. Full details on both previously introduced and new coupling mechanisms are defined. Finally, the impact of self-consistently including the ring current on the magnetosphere-ionosphere system is illustrated via a set of example simulations.« less

Chlorine incorporation in silicon films deposited by low-pressure rf discharges in gas mixtures of SICL/sub 4/ + H/sup 2/ + AR

DOE Office of Scientific and Technical Information (OSTI.GOV)

Manory, R; Auni, R; Grill, A

1984-12-01

Silicon films were deposited from tetrachlorosilane by its dissociation in argon and hydrogen rf plasma at a pressure of 2 Torr. The concentration of chlorine incorporated in the films was found to be dependent on the macrovariables of the plasma such as power input and substrate position in the plasma reactor. Mass spectrometric measurements of the plasma showed that the concentration of HCI in the plasma was strongly dependent on the power input and on position in the plasma along the gas stream. At high input powers the HCI formed in the plasma dissociates to free radicals, contributing to amore » recombination process in the gas phase and codeposition with silicon on the substrate. The correlation between the HCI reactions in the plasma and the incorporation of CL in the deposit is shown.« less

Simulations of Control Schemes for Inductively Coupled Plasma Sources

NASA Astrophysics Data System (ADS)

Ventzek, P. L. G.; Oda, A.; Shon, J. W.; Vitello, P.

1997-10-01

Process control issues are becoming increasingly important in plasma etching. Numerical experiments are an excellent test-bench for evaluating a proposed control system. Models are generally reliable enough to provide information about controller robustness, fitness of diagnostics. We will present results from a two dimensional plasma transport code with a multi-species plasma chemstry obtained from a global model. [1-2] We will show a correlation of external etch parameters (e.g. input power) with internal plasma parameters (e.g. species fluxes) which in turn are correlated with etch results (etch rate, uniformity, and selectivity) either by comparison to experiment or by using a phenomenological etch model. After process characterization, a control scheme can be evaluated since the relationship between the variable to be controlled (e.g. uniformity) is related to the measurable variable (e.g. a density) and external parameter (e.g. coil current). We will present an evaluation using the HBr-Cl2 system as an example. [1] E. Meeks and J. W. Shon, IEEE Trans. on Plasma Sci., 23, 539, 1995. [2] P. Vitello, et al., IEEE Trans. on Plasma Sci., 24, 123, 1996.

A 1D ion species model for an RF driven negative ion source

NASA Astrophysics Data System (ADS)

Turner, I.; Holmes, A. J. T.

2017-08-01

A one-dimensional model for an RF driven negative ion source has been developed based on an inductive discharge. The RF source differs from traditional filament and arc ion sources because there are no primary electrons present, and is simply composed of an antenna region (driver) and a main plasma discharge region. However the model does still make use of the classical plasma transport equations for particle energy and flow, which have previously worked well for modelling DC driven sources. The model has been developed primarily to model the Small Negative Ion Facility (SNIF) ion source at CCFE, but may be easily adapted to model other RF sources. Currently the model considers the hydrogen ion species, and provides a detailed description of the plasma parameters along the source axis, i.e. plasma temperature, density and potential, as well as current densities and species fluxes. The inputs to the model are currently the RF power, the magnetic filter field and the source gas pressure. Results from the model are presented and where possible compared to existing experimental data from SNIF, with varying RF power, source pressure.

Computational study of sheath structure in oxygen containing plasmas at medium pressures

NASA Astrophysics Data System (ADS)

Hrach, Rudolf; Novak, Stanislav; Ibehej, Tomas; Hrachova, Vera

2016-09-01

Plasma mixtures containing active species are used in many plasma-assisted material treatment technologies. The analysis of such systems is rather difficult, as both physical and chemical processes affect plasma properties. A combination of experimental and computational approaches is the best suited, especially at higher pressures and/or in chemically active plasmas. The first part of our study of argon-oxygen mixtures was based on experimental results obtained in the positive column of DC glow discharge. The plasma was analysed by the macroscopic kinetic approach which is based on the set of chemical reactions in the discharge. The result of this model is a time evolution of the number densities of each species. In the second part of contribution the detailed analysis of processes taking place during the interaction of oxygen containing plasma with immersed substrates was performed, the results of the first model being the input parameters. The used method was the particle simulation technique applied to multicomponent plasma. The sheath structure and fluxes of charged particles to substrates were analysed in the dependence on plasma pressure, plasma composition and surface geometry.

Modelling extended chromospheres

NASA Technical Reports Server (NTRS)

Linsky, J. L.

1986-01-01

Attention is given to the concept that the warm, partially ionized plasma (presently called chromosphere) associated with such stars as Alpha Boo and Rho Per extends outwards at least several photospheric radii. Calculations are presented for the Mg II K line in light of two input model atmospheres. Specific predictions are deduced from the results obtained by each of the two models.

Experimental validation of a Lyapunov-based controller for the plasma safety factor and plasma pressure in the TCV tokamak

NASA Astrophysics Data System (ADS)

Mavkov, B.; Witrant, E.; Prieur, C.; Maljaars, E.; Felici, F.; Sauter, O.; the TCV-Team

2018-05-01

In this paper, model-based closed-loop algorithms are derived for distributed control of the inverse of the safety factor profile and the plasma pressure parameter β of the TCV tokamak. The simultaneous control of the two plasma quantities is performed by combining two different control methods. The control design of the plasma safety factor is based on an infinite-dimensional setting using Lyapunov analysis for partial differential equations, while the control of the plasma pressure parameter is designed using control techniques for single-input and single-output systems. The performance and robustness of the proposed controller is analyzed in simulations using the fast plasma transport simulator RAPTOR. The control is then implemented and tested in experiments in TCV L-mode discharges using the RAPTOR model predicted estimates for the q-profile. The distributed control in TCV is performed using one co-current and one counter-current electron cyclotron heating actuation.

Minimum reaction network necessary to describe Ar/CF4 plasma etch

NASA Astrophysics Data System (ADS)

Helpert, Sofia; Chopra, Meghali; Bonnecaze, Roger T.

2018-03-01

Predicting the etch and deposition profiles created using plasma processes is challenging due to the complexity of plasma discharges and plasma-surface interactions. Volume-averaged global models allow for efficient prediction of important processing parameters and provide a means to quickly determine the effect of a variety of process inputs on the plasma discharge. However, global models are limited based on simplifying assumptions to describe the chemical reaction network. Here a database of 128 reactions is compiled and their corresponding rate constants collected from 24 sources for an Ar/CF4 plasma using the platform RODEo (Recipe Optimization for Deposition and Etching). Six different reaction sets were tested which employed anywhere from 12 to all 128 reactions to evaluate the impact of the reaction database on particle species densities and electron temperature. Because many the reactions used in our database had conflicting rate constants as reported in literature, we also present a method to deal with those uncertainties when constructing the model which includes weighting each reaction rate and filtering outliers. By analyzing the link between a reaction's rate constant and its impact on the predicted plasma densities and electron temperatures, we determine the conditions at which a reaction is deemed necessary to the plasma model. The results of this study provide a foundation for determining which minimal set of reactions must be included in the reaction set of the plasma model.

The ITER ICRF Antenna Design with TOPICA

NASA Astrophysics Data System (ADS)

Milanesio, Daniele; Maggiora, Riccardo; Meneghini, Orso; Vecchi, Giuseppe

2007-11-01

TOPICA (Torino Polytechnic Ion Cyclotron Antenna) code is an innovative tool for the 3D/1D simulation of Ion Cyclotron Radio Frequency (ICRF), i.e. accounting for antennas in a realistic 3D geometry and with an accurate 1D plasma model [1]. The TOPICA code has been deeply parallelized and has been already proved to be a reliable tool for antennas design and performance prediction. A detailed analysis of the 24 straps ITER ICRF antenna geometry has been carried out, underlining the strong dependence and asymmetries of the antenna input parameters due to the ITER plasma response. We optimized the antenna array geometry dimensions to maximize loading, lower mutual couplings and mitigate sheath effects. The calculated antenna input impedance matrices are TOPICA results of a paramount importance for the tuning and matching system design. Electric field distributions have been also calculated and they are used as the main input for the power flux estimation tool. The designed optimized antenna is capable of coupling 20 MW of power to plasma in the 40 -- 55 MHz frequency range with a maximum voltage of 45 kV in the feeding coaxial cables. [1] V. Lancellotti et al., Nuclear Fusion, 46 (2006) S476-S499

Quantification of 18F-fluorocholine kinetics in patients with prostate cancer.

PubMed

Verwer, Eline E; Oprea-Lager, Daniela E; van den Eertwegh, Alfons J M; van Moorselaar, Reindert J A; Windhorst, Albert D; Schwarte, Lothar A; Hendrikse, N Harry; Schuit, Robert C; Hoekstra, Otto S; Lammertsma, Adriaan A; Boellaard, Ronald

2015-03-01

Choline kinase is upregulated in prostate cancer, resulting in increased (18)F-fluoromethylcholine uptake. This study used pharmacokinetic modeling to validate the use of simplified methods for quantification of (18)F-fluoromethylcholine uptake in a routine clinical setting. Forty-minute dynamic PET/CT scans were acquired after injection of 204 ± 9 MBq of (18)F-fluoromethylcholine, from 8 patients with histologically proven metastasized prostate cancer. Plasma input functions were obtained using continuous arterial blood-sampling as well as using image-derived methods. Manual arterial blood samples were used for calibration and correction for plasma-to-blood ratio and metabolites. Time-activity curves were derived from volumes of interest in all visually detectable lymph node metastases. (18)F-fluoromethylcholine kinetics were studied by nonlinear regression fitting of several single- and 2-tissue plasma input models to the time-activity curves. Model selection was based on the Akaike information criterion and measures of robustness. In addition, the performance of several simplified methods, such as standardized uptake value (SUV), was assessed. Best fits were obtained using an irreversible compartment model with blood volume parameter. Parent fractions were 0.12 ± 0.4 after 20 min, necessitating individual metabolite corrections. Correspondence between venous and arterial parent fractions was low as determined by the intraclass correlation coefficient (0.61). Results for image-derived input functions that were obtained from volumes of interest in blood-pool structures distant from tissues of high (18)F-fluoromethylcholine uptake yielded good correlation to those for the blood-sampling input functions (R(2) = 0.83). SUV showed poor correlation to parameters derived from full quantitative kinetic analysis (R(2) < 0.34). In contrast, lesion activity concentration normalized to the integral of the blood activity concentration over time (SUVAUC) showed good correlation (R(2) = 0.92 for metabolite-corrected plasma; 0.65 for whole-blood activity concentrations). SUV cannot be used to quantify (18)F-fluoromethylcholine uptake. A clinical compromise could be SUVAUC derived from 2 consecutive static PET scans, one centered on a large blood-pool structure during 0-30 min after injection to obtain the blood activity concentrations and the other a whole-body scan at 30 min after injection to obtain lymph node activity concentrations. © 2015 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

Investigation of the spatial structure and developmental dynamics of near-Earth plasma perturbations under the action of powerful HF radio waves

DOE Office of Scientific and Technical Information (OSTI.GOV)

Belov, A. S., E-mail: alexis-belov@yandex.ru

2015-10-15

Results of numerical simulations of the near-Earth plasma perturbations induced by powerful HF radio waves from the SURA heating facility are presented. The simulations were performed using a modified version of the SAMI2 ionospheric model for the input parameters corresponding to the series of in-situ SURA–DEMETER experiments. The spatial structure and developmental dynamics of large-scale plasma temperature and density perturbations have been investigated. The characteristic formation and relaxation times of the induced large-scale plasma perturbations at the altitudes of the Earth’s outer ionosphere have been determined.

Self-consistent modeling of electron cyclotron resonance ion sources

NASA Astrophysics Data System (ADS)

Girard, A.; Hitz, D.; Melin, G.; Serebrennikov, K.; Lécot, C.

2004-05-01

In order to predict the performances of electron cyclotron resonance ion source (ECRIS), it is necessary to perfectly model the different parts of these sources: (i) magnetic configuration; (ii) plasma characteristics; (iii) extraction system. The magnetic configuration is easily calculated via commercial codes; different codes also simulate the ion extraction, either in two dimension, or even in three dimension (to take into account the shape of the plasma at the extraction influenced by the hexapole). However the characteristics of the plasma are not always mastered. This article describes the self-consistent modeling of ECRIS: we have developed a code which takes into account the most important construction parameters: the size of the plasma (length, diameter), the mirror ratio and axial magnetic profile, whether a biased probe is installed or not. These input parameters are used to feed a self-consistent code, which calculates the characteristics of the plasma: electron density and energy, charge state distribution, plasma potential. The code is briefly described, and some of its most interesting results are presented. Comparisons are made between the calculations and the results obtained experimentally.

The flow of plasma in the solar terrestrial environment

NASA Technical Reports Server (NTRS)

Schunk, R. W.

1992-01-01

The overall goal of our NASA Theory Program is to study the coupling, time delays, and feedback mechanisms between the various regions of the solar-terrestrial system in a self-consistent, quantitative manner. To accomplish this goal, it will eventually be necessary to have time-dependent macroscopic models of the different regions of the solar-terrestrial system and we are continually working toward this goal. However, our immediate emphasis is on the near-earth plasma environment, including the ionosphere, the plasmasphere, and the polar wind. In this area, we have developed unique global models that allow us to study the coupling between the different regions. Another important aspect of our NASA Theory Program concerns the effect that localized structure has on the macroscopic flow in the ionosphere, plasmasphere, thermosphere, and polar wind. The localized structure can be created by structured magnetospheric inputs (i.e., structured plasma convection, particle precipitation or Birkeland current patterns) or time variations in these inputs due to storms and substorms. Also, some of the plasma flows that we predict with our macroscopic models may be unstable, and another one of our goals is to examine the stability of our predicted flows. Because time-dependent, three-dimensional numerical models of the solar-terrestrial environment generally require extensive computer resources, they are usually based on relatively simple mathematical formulations (i.e., simple MHD or hydrodynamic formulation). Therefore, another long-range goal of our NASA Theory Program is to study the conditions under which various mathematical formulations can be applied to specific solar-terrestrial regions. This may involve a detailed comparison of kinetic, semikinetic, and hydrodynamic predictions for a given polar wind scenario or it may involve the comparison of a small-scale particle-in-cell (PIC) simulation of a plasma expansion event with a similar macroscopic expansion event. The different mathematical formulations have different strengths and weaknesses and a careful comparison of model predictions for similar geophysical situations will provide insight into when the various models can be used with confidence.

A comparative study of radiofrequency antennas for Helicon plasma sources

NASA Astrophysics Data System (ADS)

Melazzi, D.; Lancellotti, V.

2015-04-01

Since Helicon plasma sources can efficiently couple power and generate high-density plasma, they have received interest also as spacecraft propulsive devices, among other applications. In order to maximize the power deposited into the plasma, it is necessary to assess the performance of the radiofrequency (RF) antenna that drives the discharge, as typical plasma parameters (e.g. the density) are varied. For this reason, we have conducted a comparative analysis of three Helicon sources which feature different RF antennas, namely, the single-loop, the Nagoya type-III and the fractional helix. These antennas are compared in terms of input impedance and induced current density; in particular, the real part of the impedance constitutes a measure of the antenna ability to couple power into the plasma. The results presented in this work have been obtained through a full-wave approach which (being hinged on the numerical solution of a system of integral equations) allows computing the antenna current and impedance self-consistently. Our findings indicate that certain combinations of plasma parameters can indeed maximize the real part of the input impedance and, thus, the deposited power, and that one of the three antennas analyzed performs best for a given plasma. Furthermore, unlike other strategies which rely on approximate antenna models, our approach enables us to reveal that the antenna current density is not spatially uniform, and that a correlation exists between the plasma parameters and the spatial distribution of the current density.

Analysis and characterization of microwave plasma generated with rectangular all-dielectric resonators

NASA Astrophysics Data System (ADS)

Kourtzanidis, K.; Raja, L. L.

2017-04-01

We report on a computational modeling study of small scale plasma discharge formation with rectangular dielectric resonators (DR). An array of rectangular dielectric slabs, separated by a gap of millimeter dimensions is used to provide resonant response when illuminated by an incident wave of 1.26 GHz. A coupled electromagnetic (EM) wave-plasma model is used to describe the breakdown, early response and steady state of the argon discharge. We characterize the plasma generation with respect to the input power, background gas pressure and gap size. It is found that the plasma discharge is generated mainly inside the gaps between the DR at positions that correspond to the antinodes of the resonant enhanced electric field pattern. The enhancement of the electric field inside the gaps is due to a combination of leaking and displacement current radiation from the DR. The plasma is sustained in over-critical densities due to the large skin depth with respect to the gap and plasma size. Electron densities are calculated in the order of {10}18{--}{10}19 {{{m}}}-3 for a gas pressure of 10 Torr, while they exceed 1020 {{{m}}}-3 in atmospheric conditions. Increase of input power leads to more intense ionization and thus faster plasma formation and results to a more symmetric plasma pattern. For low background gas pressure the discharge is diffusive and extends away from the gap region while in high pressure it is constricted inside the gap. An optimal gap size can be found to provide maximum EM energy transfer to the plasma. This fact demonstrates that the gap size dictates to a certain extent the resonant frequency and the Q-factor of the dielectric array and the breakdown fields can not be determined in a straight-forward way but they are functions of the resonators geometry and incident field frequency.

Fluid and Electrolyte Balance model (FEB)

NASA Technical Reports Server (NTRS)

Fitzjerrell, D. G.

1973-01-01

The effects of various oral input water loads on solute and water distribution throughout the body are presented in the form of a model. The model was a three compartment model; the three compartments being plasma, interstitial fluid and cellular fluid. Sodium, potassium, chloride and urea were the only major solutes considered explicitly. The control of body water and electrolyte distribution was affected via drinking and hormone levels.

IMPROVED DERIVATION OF INPUT FUNCTION IN DYNAMIC MOUSE [18F]FDG PET USING BLADDER RADIOACTIVITY KINETICS

PubMed Central

Wong, Koon-Pong; Zhang, Xiaoli; Huang, Sung-Cheng

2013-01-01

Purpose Accurate determination of the plasma input function (IF) is essential for absolute quantification of physiological parameters in positron emission tomography (PET). However, it requires an invasive and tedious procedure of arterial blood sampling that is challenging in mice because of the limited blood volume. In this study, a hybrid modeling approach is proposed to estimate the plasma IF of 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) in mice using accumulated radioactivity in urinary bladder together with a single late-time blood sample measurement. Methods Dynamic PET scans were performed on nine isoflurane-anesthetized male C57BL/6 mice after a bolus injection of [18F]FDG at the lateral caudal vein. During a 60- or 90-min scan, serial blood samples were taken from the femoral artery. Image data were reconstructed using filtered backprojection with CT-based attenuation correction. Total accumulated radioactivity in the urinary bladder was fitted to a renal compartmental model with the last blood sample and a 1-exponential function that described the [18F]FDG clearance in blood. Multiple late-time blood sample estimates were calculated by the blood [18F]FDG clearance equation. A sum of 4-exponentials was assumed for the plasma IF that served as a forcing function to all tissues. The estimated plasma IF was obtained by simultaneously fitting the [18F]FDG model to the time-activity curves (TACs) of liver and muscle and the forcing function to early (0–1 min) left-ventricle data (corrected for delay, dispersion, partial-volume effects and erythrocytes uptake) and the late-time blood estimates. Using only the blood sample acquired at the end of the study to estimate the IF and the use of liver TAC as an alternative IF were also investigated. Results The area under the plasma TACs calculated for all studies using the hybrid approach was not significantly different from that using all blood samples. [18F]FDG uptake constants in brain, myocardium, skeletal muscle and liver computed by the Patlak analysis using estimated and measured plasma TACs were in excellent agreement (slope ~ 1; R2 > 0.938). The IF estimated using only the last blood sample acquired at the end of the study and the use of liver TAC as plasma IF provided less reliable results. Conclusions The estimated plasma IFs obtained with the hybrid model agreed well with those derived from arterial blood sampling. Importantly, the proposed method obviates the need of arterial catheterization, making it possible to perform repeated dynamic [18F]FDG PET studies on the same animal. Liver TAC is unsuitable as an input function for absolute quantification of [18F]FDG PET data. PMID:23322346

The effect of the plasma needle on the human keratinocytes related to the wound healing process

NASA Astrophysics Data System (ADS)

Korolov, Ihor; Fazekas, Barbara; Széll, Márta; Kemény, Lajos; Kutasi, Kinga

2016-01-01

In the present study we aim to verify the influence of a non-thermal atmospheric pressure plasma on the wound healing process. In this process the major contributors are the keratinocytes, which migrate to fill in the gap created by the wound. Therefore, we performed the direct treatment of HPV-immortalized human keratinocytes, protected by a layer of phosphate buffered saline (PBS) solution, with the glow discharge generated in flowing helium by a plasma needle. To mimick a wound, a 4 mm scratch was performed on the cell culture (scratch assay). We conducted two types of experiments: (i) cell proliferation and (ii) wound-healing model experiments. The plasma needle configuration, the plasma treatment conditions and the thickness of the protecting PBS layer were set based on viability experiments. The proliferation studies showed that short, 5-10 s, and low power treatments, such as 18 W and 20 W input power, could positively influence the cell proliferation when keratinocytes were protected by PBS. On the other hand, the plasma treatment of cell medium covered keratinocytes resulted in the decrease of proliferation. The wound-healing model (scratch assay) studies showed, that there was a maximum in the wound reduction as a function of the input power and treatment time, namely, at 18 W and 5 s. Furthermore, the wound reduction strongly depended on the treated cell—PBS interaction time. To mimic an infected wound, the scratch assay was covered with a 1× {{10}9} cfu ml-1 Propionibacterium acnes suspension. The plasma treatment of this infected assay resulted in closing of the scratch, while in the non-treated assay the wound did not close at all.

Pulsed-DC DBD Plasma Actuators

NASA Astrophysics Data System (ADS)

Duong, Alan; Corke, Thomas; Thomas, Flint

2017-11-01

A power system for dielectric barrier discharge (DBD) plasma actuators that utilizes a pulsed-DC waveform is presented. The plasma actuator arrangement is identical to most typical AC-DBD designs with staggered electrodes that are separated by a dielectric insulator. A key difference is that the pulsed-DC actuator utilizes a DC voltage source to drive the actuator instead of an AC voltage input. The DC source is supplied to both electrodes. The exposed electrode remains constant in time while the encapsulated electrode is periodically grounded for short instances then is allowed to rise to the source DC level. Further investigation of the pulsed-DC plasma actuator was conducted. Time-resolved velocity measurements were done to characterize the induced velocity field generated by the pulsed-DC plasma actuator. A model of the pulsed-DC plasma actuator is developed in LTspice for further study. The work presented are intended in developing a model to be used in CFD flow control simulations. NASA SBIR NNX14CC12C.

Profile control simulations and experiments on TCV: a controller test environment and results using a model-based predictive controller

NASA Astrophysics Data System (ADS)

Maljaars, E.; Felici, F.; Blanken, T. C.; Galperti, C.; Sauter, O.; de Baar, M. R.; Carpanese, F.; Goodman, T. P.; Kim, D.; Kim, S. H.; Kong, M.; Mavkov, B.; Merle, A.; Moret, J. M.; Nouailletas, R.; Scheffer, M.; Teplukhina, A. A.; Vu, N. M. T.; The EUROfusion MST1-team; The TCV-team

2017-12-01

The successful performance of a model predictive profile controller is demonstrated in simulations and experiments on the TCV tokamak, employing a profile controller test environment. Stable high-performance tokamak operation in hybrid and advanced plasma scenarios requires control over the safety factor profile (q-profile) and kinetic plasma parameters such as the plasma beta. This demands to establish reliable profile control routines in presently operational tokamaks. We present a model predictive profile controller that controls the q-profile and plasma beta using power requests to two clusters of gyrotrons and the plasma current request. The performance of the controller is analyzed in both simulation and TCV L-mode discharges where successful tracking of the estimated inverse q-profile as well as plasma beta is demonstrated under uncertain plasma conditions and the presence of disturbances. The controller exploits the knowledge of the time-varying actuator limits in the actuator input calculation itself such that fast transitions between targets are achieved without overshoot. A software environment is employed to prepare and test this and three other profile controllers in parallel in simulations and experiments on TCV. This set of tools includes the rapid plasma transport simulator RAPTOR and various algorithms to reconstruct the plasma equilibrium and plasma profiles by merging the available measurements with model-based predictions. In this work the estimated q-profile is merely based on RAPTOR model predictions due to the absence of internal current density measurements in TCV. These results encourage to further exploit model predictive profile control in experiments on TCV and other (future) tokamaks.

Perturbed-input-data ensemble modeling of magnetospheric dynamics

NASA Astrophysics Data System (ADS)

Morley, S.; Steinberg, J. T.; Haiducek, J. D.; Welling, D. T.; Hassan, E.; Weaver, B. P.

2017-12-01

Many models of Earth's magnetospheric dynamics - including global magnetohydrodynamic models, reduced complexity models of substorms and empirical models - are driven by solar wind parameters. To provide consistent coverage of the upstream solar wind these measurements are generally taken near the first Lagrangian point (L1) and algorithmically propagated to the nose of Earth's bow shock. However, the plasma and magnetic field measured near L1 is a point measurement of an inhomogeneous medium, so the individual measurement may not be sufficiently representative of the broader region near L1. The measured plasma may not actually interact with the Earth, and the solar wind structure may evolve between L1 and the bow shock. To quantify uncertainties in simulations, as well as to provide probabilistic forecasts, it is desirable to use perturbed input ensembles of magnetospheric and space weather forecasting models. By using concurrent measurements of the solar wind near L1 and near the Earth, we construct a statistical model of the distributions of solar wind parameters conditioned on their upstream value. So that we can draw random variates from our model we specify the conditional probability distributions using Kernel Density Estimation. We demonstrate the utility of this approach using ensemble runs of selected models that can be used for space weather prediction.

Cost of Purchased Versus Produced Plasma from Donor Recruitment Through Transfusion.

PubMed

Prioli, Katherine M; Pizzi, Laura T; Karp, Julie Katz; Galanis, Taki; Herman, Jay H

2016-10-01

Plasma is used to treat acquired coagulopathy or thrombotic thrombocytopenic purpura, or to reverse warfarin effect. Scant data are available, however, about its costs. To estimate total costs of plasma from production through administration, from the perspective of a US hospital blood donor center (BDC). Six sequential decision analytic models were constructed and informed by primary and secondary data on time, tasks, personnel, and supplies for donation, processing, and administration. Expected values of the models were summed to yield the BDC's total cost of producing, preparing, and transfusing plasma. Costs ($US 2015) are reported for a typical patient using three units of plasma. Models assume plasma was obtained from whole blood donation and transfused in an inpatient setting. Univariate sensitivity analyses were performed to test the impact of changing inputs for personnel costs and adverse event (AE) rates and costs. BDC production cost of plasma was $91.24/patient ($30.41/unit), a $30.16/patient savings versus purchased plasma. Administration and monitoring costs totaled $194.64/patient. Sensitivity analyses indicated that modifying BDC personnel costs during donation and processing has little impact on total plasma costs. However, the probability and cost of transfusion-associated circulatory overload (TACO) have a significant impact on costs. Plasma produced by our BDC may be less costly than purchased plasma. Though plasma processes have multiple tasks involving staff time, these are not the largest cost driver. Major plasma-related AEs are uncommon, but are the biggest driver of total plasma costs.

Reduction of Spectral Interferences in Inductively Coupled Plasma-Atomic Emission Spectrometry by Selective Spectral-Line Modulation.

DTIC Science & Technology

1982-05-13

11/03 laboratory mini- computer (Maynard, MA) Boxcar Amplifier: Model 162 Boxcar averager with model 164 input gates (Princeton Applied Research Corp...nn! Office Attn: Der A. B. Amster, Attn: Dv. I. P. Peebles Chemitry Division .%,!l3I1rg 1;4, Section D China Lake, California 93555 666 Summer

Predicting electromagnetic ion cyclotron wave amplitude from unstable ring current plasma conditions

DOE PAGES

Fu, Xiangrong; Cowee, Misa M.; Jordanova, Vania K.; ...

2016-11-01

Electromagnetic ion cyclotron (EMIC) waves in the Earth's inner magnetosphere are enhanced fluctuations driven unstable by ring current ion temperature anisotropy. EMIC waves can resonate with relativistic electrons and play an important role in precipitation of MeV radiation belt electrons. In this study, we investigate the excitation and saturation of EMIC instability in a homogeneous plasma using both linear theory and nonlinear hybrid simulations. We have explored a four-dimensional parameter space, carried out a large number of simulations, and derived a scaling formula that relates the saturation EMIC wave amplitude to initial plasma conditions. Finally, such scaling can be usedmore » in conjunction with ring current models like ring current-atmosphere interactions model with self-consistent magnetic field to provide global dynamic EMIC wave maps that will be more accurate inputs for radiation belt modeling than statistical models.« less

A simple model of fluid flow and electrolyte balance in the body

NASA Technical Reports Server (NTRS)

White, R. J.; Neal, L.

1973-01-01

The model is basically a three-compartment model, the three compartments being the plasma, interstitial fluid and cellular fluid. Sodium, potassium, chloride and urea are the only major solutes considered explicitly. The control of body water and electrolyte distribution is affected via drinking and hormone levels. Basically, the model follows the effect of various oral input water loads on solute and water distribution throughout the body.

Modeling of laser induced air plasma and shock wave dynamics using 2D-hydrodynamic simulations

NASA Astrophysics Data System (ADS)

Paturi, Prem Kiran; S, Sai Shiva; Chelikani, Leela; Ikkurthi, Venkata Ramana; C. D., Sijoy; Chaturvedi, Shashank; Acrhem, University Of Hyderabad Team; Computational Analysis Division, Bhabha Atomic Research Centre, Visakhapatnam Team

2017-06-01

The laser induced air plasma dynamics and the SW evolution modeled using the two dimensional hydrodynamic code by considering two different EOS: ideal gas EOS with charge state effects taken into consideration and Chemical Equilibrium applications (CEA) EOS considering the chemical kinetics of different species will be presented. The inverse bremsstrahlung absorption process due to electron-ion and electron-neutrals is considered for the laser-air interaction process for both the models. The numerical results obtained with the two models were compared with that of the experimental observations over the time scales of 200 - 4000 ns at an input laser intensity of 2.3 ×1010 W/cm2. The comparison shows that the plasma and shock dynamics differ significantly for two EOS considered. With the ideas gas EOS the asymmetric expansion and the subsequent plasma dynamics have been well reproduced as observed in the experiments, whereas with the CEA model these processes were not reproduced due to the laser energy absorption occurring mostly at the focal volume. ACRHEM team thank DRDO, India for funding.

Transition Region Emission and the Energy Input to Thermal Plasma in Solar Flares

NASA Technical Reports Server (NTRS)

Holman, Gordon D.; Holman, Gordon D.; Dennis, Brian R.; Haga, Leah; Raymond, John C.; Panasyuk, Alexander

2005-01-01

Understanding the energetics of solar flares depends on obtaining reliable determinations of the energy input to flare plasma. X-ray observations of the thermal bremsstrahlung from hot flare plasma provide temperatures and emission measures which, along with estimates of the plasma volume, allow the energy content of this hot plasma to be computed. However, if thermal energy losses are significant or if significant energy goes directly into cooler plasma, this is only a lower limit on the total energy injected into thermal plasma during the flare. We use SOHO UVCS observations of O VI flare emission scattered by coronal O VI ions to deduce the flare emission at transition region temperatures between 100,000 K and 1 MK for the 2002 July 23 and other flares. We find that the radiated energy at these temperatures significantly increases the deduced energy input to the thermal plasma, but by an amount that is less than the uncertainty in the computed energies. Comparisons of computed thermal and nonthermal electron energies deduced from RHESSI, GOES, and UVCS are shown.

Real-Time State Estimation and Long-Term Model Adaptation: A Two-Sided Approach toward Personalized Diagnosis of Glucose and Insulin Levels

PubMed Central

Eberle, Claudia; Ament, Christoph

2012-01-01

Background With continuous glucose sensors (CGSs), it is possible to obtain a dynamical signal of the patient’s subcutaneous glucose concentration in real time. How could that information be exploited? We suggest a model-based diagnosis system with a twofold objective: real-time state estimation and long-term model parameter identification. Methods To obtain a dynamical model, Bergman’s nonlinear minimal model (considering plasma glucose G, insulin I, and interstitial insulin X) is extended by two states describing first and second insulin response. Furthermore, compartments for oral glucose and subcutaneous insulin inputs as well as for subcutaneous glucose measurement are added. The observability of states and external inputs as well as the identifiability of model parameters are assessed using the empirical observability Gramian. Signals are estimated for different nondiabetic and diabetic scenarios by unscented Kalman filter. Results (1) Observability of different state subsets is evaluated, e.g., from CGSs, {G, I} or {G, X} can be observed and the set {G, I, X} cannot. (2) Model parameters are included, e.g., it is possible to estimate the second-phase insulin response gain kG2 additionally. This can be used for model adaptation and as a diagnostic parameter that is almost zero for diabetes patients. (3) External inputs are considered, e.g., oral glucose is theoretically observable for nondiabetic patients, but estimation scenarios show that the time delay of 1 h limits application. Conclusions A real-time estimation of states (such as plasma insulin I) and parameters (such as kG2) is possible, which allows an improved real-time state prediction and a personalized model. PMID:23063042

Hybrid Model of Inhomogeneous Solar Wind Plasma Heating by Alfven Wave Spectrum: Parametric Studies

NASA Technical Reports Server (NTRS)

Ofman, L.

2010-01-01

Observations of the solar wind plasma at 0.3 AU and beyond show that a turbulent spectrum of magnetic fluctuations is present. Remote sensing observations of the corona indicate that heavy ions are hotter than protons and their temperature is anisotropic (T(sub perpindicular / T(sub parallel) >> 1). We study the heating and the acceleration of multi-ion plasma in the solar wind by a turbulent spectrum of Alfvenic fluctuations using a 2-D hybrid numerical model. In the hybrid model the protons and heavy ions are treated kinetically as particles, while the electrons are included as neutralizing background fluid. This is the first two-dimensional hybrid parametric study of the solar wind plasma that includes an input turbulent wave spectrum guided by observation with inhomogeneous background density. We also investigate the effects of He++ ion beams in the inhomogeneous background plasma density on the heating of the solar wind plasma. The 2-D hybrid model treats parallel and oblique waves, together with cross-field inhomogeneity, self-consistently. We investigate the parametric dependence of the perpendicular heating, and the temperature anisotropy in the H+-He++ solar wind plasma. It was found that the scaling of the magnetic fluctuations power spectrum steepens in the higher-density regions, and the heating is channeled to these regions from the surrounding lower-density plasma due to wave refraction. The model parameters are applicable to the expected solar wind conditions at about 10 solar radii.

Alpha Heating and Burning Plasmas in Inertial Confinement Fusion.

PubMed

Betti, R; Christopherson, A R; Spears, B K; Nora, R; Bose, A; Howard, J; Woo, K M; Edwards, M J; Sanz, J

2015-06-26

Estimating the level of alpha heating and determining the onset of the burning plasma regime is essential to finding the path towards thermonuclear ignition. In a burning plasma, the alpha heating exceeds the external input energy to the plasma. Using a simple model of the implosion, it is shown that a general relation can be derived, connecting the burning plasma regime to the yield enhancement due to alpha heating and to experimentally measurable parameters such as the Lawson ignition parameter. A general alpha-heating curve is found, independent of the target and suitable to assess the performance of all laser fusion experiments whether direct or indirect drive. The onset of the burning plasma regime inside the hot spot of current implosions on the National Ignition Facility requires a fusion yield of about 50 kJ.

Tests of Transport Theory and Reduced Impurity Influx with Highly Radiative Plasmas in TFTR

NASA Astrophysics Data System (ADS)

Hill, K. W.

1997-11-01

The electron and ion temperature profiles in beam-heated plasmas were observed to be remarkably invariant when radiative losses were increased significantly through gas puffing of high-Z impurities (argon, krypton, xenon) in the Tokamak Fusion Test Reactor. Without impurity puffing, radiative losses accounted for typically only ~ 25\\char'45 of the input power and the radiation profile was strongly peaked at the plasma edge, where the dominant carbon impurity was not fully stripped. At central electron temperatures, T_eo, of ~ 6 keV, trace concentrations of krypton and xenon (n_z/ne ~ 10-3) generated flat and centrally peaked radiation profiles respectively, and a significant fraction of the input power (45-100\\char'45 ) was lost through radiation. This loss provided a nearly ideal technique for studying local heat transport in tokamaks because it perturbed the net heating profile strongly and in a measureable way, with little effect on the density and the beam deposition profiles. In supershot plasmas, Ti >> T_e, the ion temperature profile remained constant, or even increased modestly, as the radiated power fraction was increased to 75-90\\char'45 with krypton and xenon. This observation is surprising because ion-electron coupling is the dominant power loss term for the ions in the core of supershot plasmas, and the central Ti would have decreased a factor of two if the local ion thermal diffusivity had remained constant at its value without impurity puffing. In L-mode plasmas where ion-electron power coupling is a smaller term in the power balance, the electron temperature during impurity puffing also changed only ~ 10-15\\char'45 even as the net power flow through the electrons was decreased by a factor of ~ 3. The ``stiffness" of the temperature profiles to net input power is supportive of transport mechanisms which have a marginal-stability character. Preliminary comparisons of the temperature changes with predictions of the IFS/PPPL transport model,(M. Kotschenreuther, W. Dorland, M. A. Beer, and G. W. Hammett, Phys. Plasmas 2, 2381 (1995)) which has strong marginal-stability behavior, are reasonable; more detailed comparisons are in progress. Use of high-Z radiators did not impair fusion performance, confirming they can be used to reduce the heat flux to the plasma facing components with minimal ion dilution. At input power level s of 30-33 MW, enhanced radiation through krypton and xenon puffing eliminated serious carbon influx (carbon ``blooms") which occurred in comparable plasmas without impurity puffing.

Numerical Investigation of Plasma Detachment in Magnetic Nozzle Experiments

NASA Technical Reports Server (NTRS)

Sankaran, Kamesh; Polzin, Kurt A.

2008-01-01

At present there exists no generally accepted theoretical model that provides a consistent physical explanation of plasma detachment from an externally-imposed magnetic nozzle. To make progress towards that end, simulation of plasma flow in the magnetic nozzle of an arcjet experiment is performed using a multidimensional numerical simulation tool that includes theoretical models of the various dispersive and dissipative processes present in the plasma. This is an extension of the simulation tool employed in previous work by Sankaran et al. The aim is to compare the computational results with various proposed magnetic nozzle detachment theories to develop an understanding of the physical mechanisms that cause detachment. An applied magnetic field topology is obtained using a magnetostatic field solver (see Fig. I), and this field is superimposed on the time-dependent magnetic field induced in the plasma to provide a self-consistent field description. The applied magnetic field and model geometry match those found in experiments by Kuriki and Okada. This geometry is modeled because there is a substantial amount of experimental data that can be compared to the computational results, allowing for validation of the model. In addition, comparison of the simulation results with the experimentally obtained plasma parameters will provide insight into the mechanisms that lead to plasma detachment, revealing how they scale with different input parameters. Further studies will focus on modeling literature experiments both for the purpose of additional code validation and to extract physical insight regarding the mechanisms driving detachment.

Double-input compartmental modeling and spectral analysis for the quantification of positron emission tomography data in oncology

NASA Astrophysics Data System (ADS)

Tomasi, G.; Kimberley, S.; Rosso, L.; Aboagye, E.; Turkheimer, F.

2012-04-01

In positron emission tomography (PET) studies involving organs different from the brain, ignoring the metabolite contribution to the tissue time-activity curves (TAC), as in the standard single-input (SI) models, may compromise the accuracy of the estimated parameters. We employed here double-input (DI) compartmental modeling (CM), previously used for [11C]thymidine, and a novel DI spectral analysis (SA) approach on the tracers 5-[18F]fluorouracil (5-[18F]FU) and [18F]fluorothymidine ([18F]FLT). CM and SA were performed initially with a SI approach using the parent plasma TAC as an input function. These methods were then employed using a DI approach with the metabolite plasma TAC as an additional input function. Regions of interest (ROIs) corresponding to healthy liver, kidneys and liver metastases for 5-[18F]FU and to tumor, vertebra and liver for [18F]FLT were analyzed. For 5-[18F]FU, the improvement of the fit quality with the DI approaches was remarkable; in CM, the Akaike information criterion (AIC) always selected the DI over the SI model. Volume of distribution estimates obtained with DI CM and DI SA were in excellent agreement, for both parent 5-[18F]FU (R2 = 0.91) and metabolite [18F]FBAL (R2 = 0.99). For [18F]FLT, the DI methods provided notable improvements but less substantial than for 5-[18F]FU due to the lower rate of metabolism of [18F]FLT. On the basis of the AIC values, agreement between [18F]FLT Ki estimated with the SI and DI models was good (R2 = 0.75) for the ROIs where the metabolite contribution was negligible, indicating that the additional input did not bias the parent tracer only-related estimates. When the AIC suggested a substantial contribution of the metabolite [18F]FLT-glucuronide, on the other hand, the change in the parent tracer only-related parameters was significant (R2 = 0.33 for Ki). Our results indicated that improvements of DI over SI approaches can range from moderate to substantial and are more significant for tracers with a high rate of metabolism. Furthermore, they showed that SA is suitable for DI modeling and can be used effectively in the analysis of PET data.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Betti, R.; Christopherson, A. R.; Spears, B. K.

Estimating the level of alpha heating and determining the onset of the burning plasma regime is essential to finding the path towards thermonuclear ignition. In a burning plasma, the alpha heating exceeds the external input energy to the plasma. Using a simple model of the implosion, it is shown that a general relation can be derived, connecting the burning plasma regime to the yield enhancement due to alpha heating and to experimentally measurable parameters such as the Lawson ignition parameter. A general alpha-heating curve is found, independent of the target and suitable to assess the performance of all laser fusionmore » experiments whether direct or indirect drive. The onset of the burning plasma regime inside the hot spot of current implosions on the National Ignition Facility requires a fusion yield of about 50 kJ.« less

Investigating GAIM-GM’s Capability to Sense Ionospheric Irregularities via Walker Satellite Constellations

DTIC Science & Technology

2015-03-26

aligned along the Earth’s geomagnetic equator [9]. Nava’s method was analyzed under the research of Fenton , who investigated GAIM-GM’s capability to handle...the plasma bubbles without additional inputs. Fenton determined that GAIM-GM handled the evolution of the plasma bubbles poorly [2]. With the results...0 0 2 2 .3 0 Z . 66 Bibliography 1. Space Environment Corporation. Ionospheric Forecast Model Version 4.4a, 2002. 2. Kenneth Fenton . Assessment of

An enhanced tokamak startup model

NASA Astrophysics Data System (ADS)

Goswami, Rajiv; Artaud, Jean-François

2017-01-01

The startup of tokamaks has been examined in the past in varying degree of detail. This phase typically involves the burnthrough of impurities and the subsequent rampup of plasma current. A zero-dimensional (0D) model is most widely used where the time evolution of volume averaged quantities determines the detailed balance between the input and loss of particle and power. But, being a 0D setup, these studies do not take into consideration the co-evolution of plasma size and shape, and instead assume an unchanging minor and major radius. However, it is known that the plasma position and its minor radius can change appreciably as the plasma evolves in time to fill in the entire available volume. In this paper, an enhanced model for the tokamak startup is introduced, which for the first time takes into account the evolution of plasma geometry during this brief but highly dynamic period by including realistic one-dimensional (1D) effects within the broad 0D framework. In addition the effect of runaway electrons (REs) has also been incorporated. The paper demonstrates that the inclusion of plasma cross section evolution in conjunction with REs plays an important role in the formation and development of tokamak startup. The model is benchmarked against experimental results from ADITYA tokamak.

Plasma-Powder Feedstock Interaction During Plasma Spray-Physical Vapor Deposition

NASA Astrophysics Data System (ADS)

Anwaar, Aleem; Wei, Lianglinag; Guo, Hongbo; Zhang, Baopeng

2017-02-01

Plasma spray-physical vapor deposition is a new process developed to produce coatings from the vapor phase. To achieve deposition from the vapor phase, the plasma-feedstock interaction inside the plasma torch, i.e., from the powder injection point to the nozzle exit, is critical. In this work, the plasma characteristics and the momentum and heat transfer between the plasma and powder feedstock at different torch input power levels were investigated theoretically to optimize the net plasma torch power, among other important factors such as the plasma gas composition, powder feed rate, and carrier gas. The plasma characteristics were calculated using the CEA2 code, and the plasma-feedstock interaction was studied inside the torch nozzle at low-pressure (20-25 kPa) conditions. A particle dynamics model was introduced to compute the particle velocity, coupled with Xi Chen's drag model for nonevaporating particles. The results show that the energy transferred to the particles and the coating morphology are greatly influenced by the plasma gas characteristics and the particle dynamics inside the nozzle. The heat transfer between the plasma gas and feedstock material increased with the net torch power up to an optimum at 64 kW, at which a maximum of 3.4% of the available plasma energy was absorbed by the feedstock powder. Experimental results using agglomerated 7-8 wt.% yttria-stabilized zirconia (YSZ) powder as feedstock material confirmed the theoretical predictions.

On the universality of power laws for tokamak plasma predictions

NASA Astrophysics Data System (ADS)

Garcia, J.; Cambon, D.; Contributors, JET

2018-02-01

Significant deviations from well established power laws for the thermal energy confinement time, obtained from extensive databases analysis as the IPB98(y,2), have been recently reported in dedicated power scans. In order to illuminate the adequacy, validity and universality of power laws as tools for predicting plasma performance, a simplified analysis has been carried out in the framework of a minimal modeling for heat transport which is, however, able to account for the interplay between turbulence and collinear effects with the input power known to play a role in experiments with significant deviations from such power laws. Whereas at low powers, the usual scaling laws are recovered with little influence of other plasma parameters, resulting in a robust power low exponent, at high power it is shown how the exponents obtained are extremely sensitive to the heating deposition, the q-profile or even the sampling or the number of points considered due to highly non-linear behavior of the heat transport. In particular circumstances, even a minimum of the thermal energy confinement time with the input power can be obtained, which means that the approach of the energy confinement time as a power law might be intrinsically invalid. Therefore plasma predictions with a power law approximation with a constant exponent obtained from a regression of a broad range of powers and other plasma parameters which can non-linearly affect and suppress heat transport, can lead to misleading results suggesting that this approach should be taken cautiously and its results continuously compared with modeling which can properly capture the underline physics, as gyrokinetic simulations.

A statistical survey of heat input parameters into the cusp thermosphere

NASA Astrophysics Data System (ADS)

Moen, J. I.; Skjaeveland, A.; Carlson, H. C.

2017-12-01

Based on three winters of observational data, we present those ionosphere parameters deemed most critical to realistic space weather ionosphere and thermosphere representation and prediction, in regions impacted by variability in the cusp. The CHAMP spacecraft revealed large variability in cusp thermosphere densities, measuring frequent satellite drag enhancements, up to doublings. The community recognizes a clear need for more realistic representation of plasma flows and electron densities near the cusp. Existing average-value models produce order of magnitude errors in these parameters, resulting in large under estimations of predicted drag. We fill this knowledge gap with statistics-based specification of these key parameters over their range of observed values. The EISCAT Svalbard Radar (ESR) tracks plasma flow Vi , electron density Ne, and electron, ion temperatures Te, Ti , with consecutive 2-3 minute windshield-wipe scans of 1000x500 km areas. This allows mapping the maximum Ti of a large area within or near the cusp with high temporal resolution. In magnetic field-aligned mode the radar can measure high-resolution profiles of these plasma parameters. By deriving statistics for Ne and Ti , we enable derivation of thermosphere heating deposition under background and frictional-drag-dominated magnetic reconnection conditions. We separate our Ne and Ti profiles into quiescent and enhanced states, which are not closely correlated due to the spatial structure of the reconnection foot point. Use of our data-based parameter inputs can make order of magnitude corrections to input data driving thermosphere models, enabling removal of previous two fold drag errors.

Experimental and modeling uncertainties in the validation of lower hybrid current drive

DOE Office of Scientific and Technical Information (OSTI.GOV)

Poli, F. M.; Bonoli, P. T.; Chilenski, M.

Our work discusses sources of uncertainty in the validation of lower hybrid wave current drive simulations against experiments, by evolving self-consistently the magnetic equilibrium and the heating and current drive profiles, calculated with a combined toroidal ray tracing code and 3D Fokker–Planck solver. The simulations indicate a complex interplay of elements, where uncertainties in the input plasma parameters, in the models and in the transport solver combine and compensate each other, at times. It is concluded that ray-tracing calculations should include a realistic representation of the density and temperature in the region between the confined plasma and the wall, whichmore » is especially important in regimes where the LH waves are weakly damped and undergo multiple reflections from the plasma boundary. Uncertainties introduced in the processing of diagnostic data as well as uncertainties introduced by model approximations are assessed. We show that, by comparing the evolution of the plasma parameters in self-consistent simulations with available data, inconsistencies can be identified and limitations in the models or in the experimental data assessed.« less

Experimental and modeling uncertainties in the validation of lower hybrid current drive

DOE PAGES

Poli, F. M.; Bonoli, P. T.; Chilenski, M.; ...

2016-07-28

Our work discusses sources of uncertainty in the validation of lower hybrid wave current drive simulations against experiments, by evolving self-consistently the magnetic equilibrium and the heating and current drive profiles, calculated with a combined toroidal ray tracing code and 3D Fokker–Planck solver. The simulations indicate a complex interplay of elements, where uncertainties in the input plasma parameters, in the models and in the transport solver combine and compensate each other, at times. It is concluded that ray-tracing calculations should include a realistic representation of the density and temperature in the region between the confined plasma and the wall, whichmore » is especially important in regimes where the LH waves are weakly damped and undergo multiple reflections from the plasma boundary. Uncertainties introduced in the processing of diagnostic data as well as uncertainties introduced by model approximations are assessed. We show that, by comparing the evolution of the plasma parameters in self-consistent simulations with available data, inconsistencies can be identified and limitations in the models or in the experimental data assessed.« less

Application of a Physiologically Based Pharmacokinetic Model to Predict OATP1B1-Related Variability in Pharmacodynamics of Rosuvastatin

PubMed Central

Rose, R H; Neuhoff, S; Abduljalil, K; Chetty, M; Rostami-Hodjegan, A; Jamei, M

2014-01-01

Typically, pharmacokinetic–pharmacodynamic (PK/PD) models use plasma concentration as the input that drives the PD model. However, interindividual variability in uptake transporter activity can lead to variable drug concentrations in plasma without discernible impact on the effect site organ concentration. A physiologically based PK/PD model for rosuvastatin was developed that linked the predicted liver concentration to the PD response model. The model was then applied to predict the effect of genotype-dependent uptake by the organic anion-transporting polypeptide 1B1 (OATP1B1) transporter on the pharmacological response. The area under the plasma concentration–time curve (AUC0–∞) was increased by 63 and 111% for the c.521TC and c.521CC genotypes vs. the c.521TT genotype, while the PD response remained relatively unchanged (3.1 and 5.8% reduction). Using local concentration at the effect site to drive the PD response enabled us to explain the observed disconnect between the effect of the OATP1B1 c521T>C polymorphism on rosuvastatin plasma concentration and the cholesterol synthesis response. PMID:25006781

AtomDB Progress Report: Atomic data and new models for X-ray spectroscopy.

NASA Astrophysics Data System (ADS)

Smith, Randall K.; Foster, Adam; Brickhouse, Nancy S.; Stancil, Phillip C.; Cumbee, Renata; Mullen, Patrick Dean; AtomDB Team

2018-06-01

The AtomDB project collects atomic data from both theoretical and observational/experimental sources, providing both a convenient interface (http://www.atomdb.org/Webguide/webguide.php) as well as providing input to spectral models for many types of astrophysical X-ray plasmas. We have released several updates to AtomDB in response to the Hitomi data, including new data for the Fe K complex, and have expanded the range of models available in AtomDB to include the Kronos charge exchange models from Mullen at al. (2016, ApJS, 224, 2). Combined with the previous AtomDB charge exchange model (http://www.atomdb.org/CX/), these data enable a velocity-dependent model for X-ray and EUV charge exchange spectra. We also present a new Kappa-distribution spectral model, enabling plasmas with non-Maxwellian electron distributions to be modeled with AtomDB. Tools are provided within pyAtomDB to explore and exploit these new plasma models. This presentation will review these enhancements and describe plans for the new few years of database and code development in preparation for XARM, Athena, and (hopefully) Arcus.

Simulation of a large size inductively coupled plasma generator and comparison with experimental data

NASA Astrophysics Data System (ADS)

Lei, Fan; Li, Xiaoping; Liu, Yanming; Liu, Donglin; Yang, Min; Yu, Yuanyuan

2018-01-01

A two-dimensional axisymmetric inductively coupled plasma (ICP) model with its implementation in the COMSOL (Multi-physics simulation software) platform is described. Specifically, a large size ICP generator filled with argon is simulated in this study. Distributions of the number density and temperature of electrons are obtained for various input power and pressure settings and compared. In addition, the electron trajectory distribution is obtained in simulation. Finally, using experimental data, the results from simulations are compared to assess the veracity of the two-dimensional fluid model. The purpose of this comparison is to validate the veracity of the simulation model. An approximate agreement was found (variation tendency is the same). The main reasons for the numerical magnitude discrepancies are the assumption of a Maxwellian distribution and a Druyvesteyn distribution for the electron energy and the lack of cross sections of collision frequencies and reaction rates for argon plasma.

Fast, Statistical Model of Surface Roughness for Ion-Solid Interaction Simulations and Efficient Code Coupling

NASA Astrophysics Data System (ADS)

Drobny, Jon; Curreli, Davide; Ruzic, David; Lasa, Ane; Green, David; Canik, John; Younkin, Tim; Blondel, Sophie; Wirth, Brian

2017-10-01

Surface roughness greatly impacts material erosion, and thus plays an important role in Plasma-Surface Interactions. Developing strategies for efficiently introducing rough surfaces into ion-solid interaction codes will be an important step towards whole-device modeling of plasma devices and future fusion reactors such as ITER. Fractal TRIDYN (F-TRIDYN) is an upgraded version of the Monte Carlo, BCA program TRIDYN developed for this purpose that includes an explicit fractal model of surface roughness and extended input and output options for file-based code coupling. Code coupling with both plasma and material codes has been achieved and allows for multi-scale, whole-device modeling of plasma experiments. These code coupling results will be presented. F-TRIDYN has been further upgraded with an alternative, statistical model of surface roughness. The statistical model is significantly faster than and compares favorably to the fractal model. Additionally, the statistical model compares well to alternative computational surface roughness models and experiments. Theoretical links between the fractal and statistical models are made, and further connections to experimental measurements of surface roughness are explored. This work was supported by the PSI-SciDAC Project funded by the U.S. Department of Energy through contract DOE-DE-SC0008658.

Microwave Plasma-Activated Chemical Vapor Deposition of Nitrogen-Doped Diamond. II: CH4/N2/H2 Plasmas

PubMed Central

2016-01-01

We report a combined experimental and modeling study of microwave-activated dilute CH4/N2/H2 plasmas, as used for chemical vapor deposition (CVD) of diamond, under very similar conditions to previous studies of CH4/H2, CH4/H2/Ar, and N2/H2 gas mixtures. Using cavity ring-down spectroscopy, absolute column densities of CH(X, v = 0), CN(X, v = 0), and NH(X, v = 0) radicals in the hot plasma have been determined as functions of height, z, source gas mixing ratio, total gas pressure, p, and input power, P. Optical emission spectroscopy has been used to investigate, with respect to the same variables, the relative number densities of electronically excited species, namely, H atoms, CH, C2, CN, and NH radicals and triplet N2 molecules. The measurements have been reproduced and rationalized from first-principles by 2-D (r, z) coupled kinetic and transport modeling, and comparison between experiment and simulation has afforded a detailed understanding of C/N/H plasma-chemical reactivity and variations with process conditions and with location within the reactor. The experimentally validated simulations have been extended to much lower N2 input fractions and higher microwave powers than were probed experimentally, providing predictions for the gas-phase chemistry adjacent to the diamond surface and its variation across a wide range of conditions employed in practical diamond-growing CVD processes. The strongly bound N2 molecule is very resistant to dissociation at the input MW powers and pressures prevailing in typical diamond CVD reactors, but its chemical reactivity is boosted through energy pooling in its lowest-lying (metastable) triplet state and subsequent reactions with H atoms. For a CH4 input mole fraction of 4%, with N2 present at 1–6000 ppm, at pressure p = 150 Torr, and with applied microwave power P = 1.5 kW, the near-substrate gas-phase N atom concentration, [N]ns, scales linearly with the N2 input mole fraction and exceeds the concentrations [NH]ns, [NH2]ns, and [CN]ns of other reactive nitrogen-containing species by up to an order of magnitude. The ratio [N]ns/[CH3]ns scales proportionally with (but is 102–103 times smaller than) the ratio of the N2 to CH4 input mole fractions for the given values of p and P, but [N]ns/[CN]ns decreases (and thus the potential importance of CN in contributing to N-doped diamond growth increases) as p and P increase. Possible insights regarding the well-documented effects of trace N2 additions on the growth rates and morphologies of diamond films formed by CVD using MW-activated CH4/H2 gas mixtures are briefly considered. PMID:27718565

A plasma rotation control scheme for NSTX and NSTX-U

NASA Astrophysics Data System (ADS)

Goumiri, Imene

2016-10-01

Plasma rotation has been proven to play a key role in stabilizing large scale instabilities and improving plasma confinement by suppressing micro-turbulence. A model-based feedback system which controls the plasma rotation profile on the National Spherical Torus Experiment (NSTX) and its upgrade (NSTX-U) is presented. The first part of this work uses experimental measurements from NSTX as a starting point and models the control of plasma rotation using two different types of actuation: momentum from injected neutral beams and neoclassical toroidal viscosity generated by three-dimensional applied magnetic fields. Whether based on the data-driven model for NSTX or purely predictive modeling for NSTX-U, a reduced order model based feedback controller was designed. Predictive simulations using the TRANSP plasma transport code with the actuator input determined by the controller (controller-in-the-loop) show that the controller drives the plasma's rotation to the desired profiles in less than 100 ms given practical constraints on the actuators and the available real-time rotation measurements. This is the first time that TRANSP has been used as a plasma in simulator in a closed feedback loop test. Another approach to control simultaneously the toroidal rotation profile as well as βN is then shown for NSTX-U. For this case, the neutral beams (actuators) have been augmented in the modeling to match the upgrade version which spread the injection throughout the edge of the plasma. Control robustness in stability and performance has then been tested and used to predict the limits of the resulting controllers when the energy confinement time (τE) and the momentum diffusivity coefficient (χϕ) vary.

The flow of plasma in the solar terrestrial environment

NASA Technical Reports Server (NTRS)

Schunk, Robert W.; Banks, P.; Barakat, A. R.; Crain, D. J.; Demars, H. G.; Lemaire, J.; Ma, T.-Z.; Rasmussen, C. E.; Richards, P.; Sica, R.

1990-01-01

The overall goal of our NASA Theory Program was to study the coupling, time delays, and feedback mechanisms between the various regions of the solar-terrestrial system in a self-consistent, quantitative manner. To accomplish this goal, it will eventually be necessary to have time-dependent macroscopic models of the different regions of the solar-terrestrial system and we are continually working toward this goal. However, with the funding from this NASA program, we concentrated on the near-earth plasma environment, including the ionosphere, the plasmasphere, and the polar wind. In this area, we developed unique global models that allowed us to study the coupling between the different regions. These results are highlighted in the next section. Another important aspect of our NASA Theory Program concerned the effect that localized 'structure' had on the macroscopic flow in the ionosphere, plasmasphere, thermosphere, and polar wind. The localized structure can be created by structured magnetospheric inputs (i.e., structured plasma convection, particle precipitation or Birkland current patterns) or time variations in these input due to storms and substorms. Also, some of the plasma flows that we predicted with our macroscopic models could be unstable, and another one of our goals was to examine the stability of our predicted flows. Because time-dependent, three-dimensional numerical models of the solar-terrestrial environment generally require extensive computer resources, they are usually based on relatively simple mathematical formulations (i.e., simple MHD or hydrodynamic formulations). Therefore, another goal of our NASA Theory Program was to study the conditions under which various mathematical formulations can be applied to specific solar-terrestrial regions. This could involve a detailed comparison of kinetic, semi-kinetic, and hydrodynamic predictions for a given polar wind scenario or it could involve the comparison of a small-scale particle-in-cell (PIC) simulation of a plasma expansion event with a similar macroscopic expansion event. The different mathematical formulations have different strengths and weaknesses and a careful comparison of model predictions for similar geophysical situations provides insight into when the various models can be used with confidence.

The flow of plasma in the solar terrestrial environment

NASA Technical Reports Server (NTRS)

Schunk, Robert W.

1991-01-01

The overall goal of our NASA Theory Program is to study the coupling, time delays, and feedback mechanisms between the various regions of the solar-terrestrial system in a self-consistent, quantitative, manner. To accomplish this goal, it will eventually be necessary to have time-dependent macroscopic models of the different regions of the solar-terrestrial system and we are continually working toward this goal. However, our immediate emphasis is on the near-earth plasma environment, including the ionosphere, the plasmasphere, and the polar wind. In this area, we have developed unique global models that allow us to study the coupling between the different regions. These results are highlighted. Another important aspect of our NASA Theory Program concerns the effect that localized structure has on the macroscopic flow in the ionosphere, plasmasphere, thermosphere and polar wind. The localized structure can be created by structured magnetospheric inputs (i.e., structured plasma convection, particle precipitation or Birkeland current patterns) or time variations in these inputs due to storms and substorms. Also, some of the plasma flows that we predict with our macroscopic models may be unstable. Another one of our goals is to examine the stability of our predicted flows. Because time-dependent three-dimensional numerical models of the solar-terrestrial environment generally require extensive computer resources, they are usually based on relatively simple mathematical formulations (i.e., simple MHD or hydrodynamic formulations). Therefore, another long-range goal of our NASA Theory Program is to study the conditions under which various mathematical formulations can be applied to specific solar-terrestrial regions. This may involve a detailed comparison of kinetic, semikinetic, and hydrodynamic predictions for a given polar wind scenario or it may involve the comparison of a small-scale particle-in-cell (PIC) simulation of a plasma expansion event with a similar macroscopic expansion event. The different mathematical formulations have different strengths and weaknesses and a careful comparison of model predictions for similar geophysical situations will provide insight into when the various models can be used with confidence.

Resource Tracking Model Updates and Trade Studies

NASA Technical Reports Server (NTRS)

Chambliss, Joe; Stambaugh, Imelda; Moore, Michael

2016-01-01

The Resource Tracking Model has been updated to capture system manager and project manager inputs. Both the Trick/General Use Nodal Network Solver Resource Tracking Model (RTM) simulator and the RTM mass balance spreadsheet have been revised to address inputs from system managers and to refine the way mass balance is illustrated. The revisions to the RTM included the addition of a Plasma Pyrolysis Assembly (PPA) to recover hydrogen from Sabatier Reactor methane, which was vented in the prior version of the RTM. The effect of the PPA on the overall balance of resources in an exploration vehicle is illustrated in the increased recycle of vehicle oxygen. Case studies have been run to show the relative effect of performance changes on vehicle resources.

Mode conversion in cold low-density plasma with a sheared magnetic field

DOE PAGES

Dodin, I. Y.; Ruiz, D. E.; Kubo, S.

2017-12-19

Here, a theory is proposed that describes mutual conversion of two electromagnetic modes in cold low-density plasma, specifically, in the high-frequency limit where the ion response is negligible. In contrast to the classic (Landau–Zener-type) theory of mode conversion, the region of resonant coupling in low-density plasma is not necessarily narrow, so the coupling matrix cannot be approximated with its first-order Taylor expansion; also, the initial conditions are set up differently. For the case of strong magnetic shear, a simple method is identified for preparing a two-mode wave such that it transforms into a single-mode wave upon entering high-density plasma. Themore » theory can be used for reduced modeling of wave-power input in fusion plasmas. In particular, applications are envisioned in stellarator research, where the mutual conversion of two electromagnetic modes near the plasma edge is a known issue.« less

Mode conversion in cold low-density plasma with a sheared magnetic field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dodin, I. Y.; Ruiz, D. E.; Kubo, S.

Here, a theory is proposed that describes mutual conversion of two electromagnetic modes in cold low-density plasma, specifically, in the high-frequency limit where the ion response is negligible. In contrast to the classic (Landau–Zener-type) theory of mode conversion, the region of resonant coupling in low-density plasma is not necessarily narrow, so the coupling matrix cannot be approximated with its first-order Taylor expansion; also, the initial conditions are set up differently. For the case of strong magnetic shear, a simple method is identified for preparing a two-mode wave such that it transforms into a single-mode wave upon entering high-density plasma. Themore » theory can be used for reduced modeling of wave-power input in fusion plasmas. In particular, applications are envisioned in stellarator research, where the mutual conversion of two electromagnetic modes near the plasma edge is a known issue.« less

Analysis of hydrogen plasma in MPCVD reactor

NASA Astrophysics Data System (ADS)

Shivkumar, Gayathri

The aim of this work is to build a numerical model that can predict the plasma properties of hydrogen plasmas inside a Seki Technotron Corp. AX5200S MPCVD system so that it may be used to understand and optimize the conditions for the growth of carbon nanostructures. A 2D model of the system is used in the finite element high frequency Maxwell solver and heat trasfer solver in COMSOL Multiphysics, where the solvers are coupled with user defined functions to analyze the plasma. A simplified chemistry model is formulated in order to determine the electron temperature in the plasma. This is used in the UDFs which calculate the electron number density as well as electron temperature. A Boltzmann equation solver for electrons in weakly ionized gases under uniform electric fields, called BOLSIG+, is used to obtain certain input parameters required for these UDFs. The system is modeled for several reactor geometries at pressures of 10 Torr and 30 Torr and powers ranging from 300 W to 700 W. The variation of plasma characteristics with changes in input conditions is studied and the electric field, electron number density, electron temperature and gas temperature are seen to increase with increasing power. Electric field, electron number density and electron temperature decrease and gas temperature increases with increasing pressure. The modeling results are compared with experimental measurements and a good agreement is found after calibrating the parameter gamma in Funer's model to match experimental electron number densities. The gas temperature is seen to have a weak dependence on power and a strong dependence on gas pressure. On an average, the gas temperature at a point 5 mm above the center of the puck increases from about 1000 K at a pressure of 10 Torr to about 1500 K at 30 Torr. The inclusion of the pillar produces an increase in the maximum electron number density of approximately 50%; it is higher under some conditions. It increases the maximum electron temperature by about 70% and at 500 W and 30 Torr, the maximum gas temperature is seen to increase by 50%. The effect of susceptor position is studied and it is seen that the only condition favorable to growth would be to raise it by less than 25 mm from the initial reference position or to maintain it at the same level.

Modeling polar cap F-region patches using time varying convection

NASA Technical Reports Server (NTRS)

Sojka, J. J.; Bowline, M. D.; Schunk, R. W.; Decker, D. T.; Valladares, C. E.; Sheehan, R.; Anderson, D. N.; Heelis, R. A.

1993-01-01

Creation of polar cap F-region patches are simulated for the first time using two independent physical models of the high latitude ionosphere. The patch formation is achieved by temporally varying the magnetospheric electric field (ionospheric convection) input to the models. The imposed convection variations are comparable to changes in the convection that result from changes in the B(y) IMF component for southward IMF. Solar maximum-winter simulations show that simple changes in the convection pattern lead to significant changes in the polar cap plasma structuring. Specifically, in winter, as enhanced dayside plasma convects into the polar cap to form the classic tongue-of-ionization the convection changes produce density structures that are indistinguishable from the observed patches.

Numerical analysis of the heat source characteristics of a two-electrode TIG arc

NASA Astrophysics Data System (ADS)

Ogino, Y.; Hirata, Y.; Nomura, K.

2011-06-01

Various kinds of multi-electrode welding processes are used to ensure high productivity in industrial fields such as shipbuilding, automotive manufacturing and pipe fabrication. However, it is difficult to obtain the optimum welding conditions for a specific product, because there are many operating parameters, and because welding phenomena are very complicated. In the present research, the heat source characteristics of a two-electrode TIG arc were numerically investigated using a 3D arc plasma model with a focus on the distance between the two electrodes. The arc plasma shape changed significantly, depending on the electrode spacing. The heat source characteristics, such as the heat input density and the arc pressure distribution, changed significantly when the electrode separation was varied. The maximum arc pressure of the two-electrode TIG arc was much lower than that of a single-electrode TIG. However, the total heat input of the two-electrode TIG arc was nearly constant and was independent of the electrode spacing. These heat source characteristics of the two-electrode TIG arc are useful for controlling the heat input distribution at a low arc pressure. Therefore, these results indicate the possibility of a heat source based on a two-electrode TIG arc that is capable of high heat input at low pressures.

Optimization of Dimensional accuracy in plasma arc cutting process employing parametric modelling approach

NASA Astrophysics Data System (ADS)

Naik, Deepak kumar; Maity, K. P.

2018-03-01

Plasma arc cutting (PAC) is a high temperature thermal cutting process employed for the cutting of extensively high strength material which are difficult to cut through any other manufacturing process. This process involves high energized plasma arc to cut any conducting material with better dimensional accuracy in lesser time. This research work presents the effect of process parameter on to the dimensional accuracy of PAC process. The input process parameters were selected as arc voltage, standoff distance and cutting speed. A rectangular plate of 304L stainless steel of 10 mm thickness was taken for the experiment as a workpiece. Stainless steel is very extensively used material in manufacturing industries. Linear dimension were measured following Taguchi’s L16 orthogonal array design approach. Three levels were selected to conduct the experiment for each of the process parameter. In all experiments, clockwise cut direction was followed. The result obtained thorough measurement is further analyzed. Analysis of variance (ANOVA) and Analysis of means (ANOM) were performed to evaluate the effect of each process parameter. ANOVA analysis reveals the effect of input process parameter upon leaner dimension in X axis. The results of the work shows that the optimal setting of process parameter values for the leaner dimension on the X axis. The result of the investigations clearly show that the specific range of input process parameter achieved the improved machinability.

Two-point modeling of SOL losses of HHFW power in NSTX

NASA Astrophysics Data System (ADS)

Kish, Ayden; Perkins, Rory; Ahn, Joon-Wook; Diallo, Ahmed; Gray, Travis; Hosea, Joel; Jaworski, Michael; Kramer, Gerrit; Leblanc, Benoit; Sabbagh, Steve

2017-10-01

High-harmonic fast-wave (HHFW) heating is a heating and current-drive scheme on the National Spherical Torus eXperiment (NSTX) complimentary to neutral beam injection. Previous experiments suggest that a significant fraction, up to 50%, of the HHFW power is promptly lost to the scrape-off layer (SOL). Research indicates that the lost power reaches the divertor via wave propagation and is converted to a heat flux at the divertor through RF rectification rather than heating the SOL plasma at the midplane. This counter-intuitive hypothesis is investigated using a simplified two-point model, relating plasma parameters at the divertor to those at the midplane. Taking measurements at the divertor region of NSTX as input, this two-point model is used to predict midplane parameters, using the predicted heat flux as an indicator of power input to the SOL. These predictions are compared to measurements at the midplane to evaluate the extent to which they are consistent with experiment. This work was made possible by funding from the Department of Energy for the Summer Undergraduate Laboratory Internship (SULI) program. This work is supported by the US DOE Contract No. DE-AC02-09CH11466.

Developing Chemistry and Kinetic Modeling Tools for Low-Temperature Plasma Simulations

NASA Astrophysics Data System (ADS)

Jenkins, Thomas; Beckwith, Kris; Davidson, Bradley; Kruger, Scott; Pankin, Alexei; Roark, Christine; Stoltz, Peter

2015-09-01

We discuss the use of proper orthogonal decomposition (POD) methods in VSim, a FDTD plasma simulation code capable of both PIC/MCC and fluid modeling. POD methods efficiently generate smooth representations of noisy self-consistent or test-particle PIC data, and are thus advantageous in computing macroscopic fluid quantities from large PIC datasets (e.g. for particle-based closure computations) and in constructing optimal visual representations of the underlying physics. They may also confer performance advantages for massively parallel simulations, due to the significant reduction in dataset sizes conferred by truncated singular-value decompositions of the PIC data. We also demonstrate how complex LTP chemistry scenarios can be modeled in VSim via an interface with MUNCHKIN, a developing standalone python/C++/SQL code that identifies reaction paths for given input species, solves 1D rate equations for the time-dependent chemical evolution of the system, and generates corresponding VSim input blocks with appropriate cross-sections/reaction rates. MUNCHKIN also computes reaction rates from user-specified distribution functions, and conducts principal path analyses to reduce the number of simulated chemical reactions. Supported by U.S. Department of Energy SBIR program, Award DE-SC0009501.

Recent advances in parametric neuroreceptor mapping with dynamic PET: basic concepts and graphical analyses.

PubMed

Seo, Seongho; Kim, Su Jin; Lee, Dong Soo; Lee, Jae Sung

2014-10-01

Tracer kinetic modeling in dynamic positron emission tomography (PET) has been widely used to investigate the characteristic distribution patterns or dysfunctions of neuroreceptors in brain diseases. Its practical goal has progressed from regional data quantification to parametric mapping that produces images of kinetic-model parameters by fully exploiting the spatiotemporal information in dynamic PET data. Graphical analysis (GA) is a major parametric mapping technique that is independent on any compartmental model configuration, robust to noise, and computationally efficient. In this paper, we provide an overview of recent advances in the parametric mapping of neuroreceptor binding based on GA methods. The associated basic concepts in tracer kinetic modeling are presented, including commonly-used compartment models and major parameters of interest. Technical details of GA approaches for reversible and irreversible radioligands are described, considering both plasma input and reference tissue input models. Their statistical properties are discussed in view of parametric imaging.

Development of a fluid model for DC arc plasma torches and its integration with downstream models of atmospheric plasma spray particle plumes

NASA Astrophysics Data System (ADS)

Cannamela, Michael J., III

The plasma spray process uses plasma flames to melt micron sized particles of e.g. ceramic and propel the droplets to impinge upon and freeze to the target workpiece, forming a functional coating. Variations in the process arise from many sources, and because sensing of the process is imperfect one is motivated to pursue a modeling approach. This dissertation models the major elements of the process; the torch that produces the plasma flame, the jet of hot plasma issuing from the torch, and the plume of particles conveyed and heated by the jet. The plasma in the torch is modeled by a one-fluid magnetohydrodynamic (MHD) approach and it is found that the MHD equations can accurately predict the power dissipated in the bulk of the plasma, while special treatment is required in regions near the electrodes. Treatment of the cathode region is eased since it can be de-coupled from the bulk flow. Treatment of the anode region aims to extract the correct amount of power from the plasma. With MHD in the bulk and these special conditions at the electrode boundaries, the net power into the plasma can be matched with experiment. For one simulation of an SG-100 torch operating at 500A, the measured net power was 7.0kW while the computed net power was 7.1kW. Using outlet information from the torch, the impact of plasma arc oscillations on the free jet and on the in-flight particle states is predicted. The model of the plasma jet is validated against the existing LAVA code, and is able to predict the fraction of entrained air in the jet to within 20% of the experimental value. The variations in particle states due to the arc fluctuations are found to be similar in size to variations due to changes in particle injection velocity, and so cannot be neglected when considering particle state distributions. The end result of this work is to make available a complete chain of models for the plasma spray process, from torch input conditions to in-flight particle state.

Carbon dioxide splitting in a dielectric barrier discharge plasma: a combined experimental and computational study.

PubMed

Aerts, Robby; Somers, Wesley; Bogaerts, Annemie

2015-02-01

Plasma technology is gaining increasing interest for the splitting of CO2 into CO and O2 . We have performed experiments to study this process in a dielectric barrier discharge (DBD) plasma with a wide range of parameters. The frequency and dielectric material did not affect the CO2 conversion and energy efficiency, but the discharge gap can have a considerable effect. The specific energy input has the most important effect on the CO2 conversion and energy efficiency. We have also presented a plasma chemistry model for CO2 splitting, which shows reasonable agreement with the experimental conversion and energy efficiency. This model is used to elucidate the critical reactions that are mostly responsible for the CO2 conversion. Finally, we have compared our results with other CO2 splitting techniques and we identified the limitations as well as the benefits and future possibilities in terms of modifications of DBD plasmas for greenhouse gas conversion in general. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

In-liquid arc plasma jet and its application to phenol degradation

NASA Astrophysics Data System (ADS)

Liu, Jing-Lin; Park, Hyun-Woo; Hamdan, Ahmad; Cha, Min Suk

2018-03-01

We present a new method for achieving chemical reactions induced by plasmas with liquids—an in-liquid arc plasma jet system—designed to have a few advantages over the existing methods. High-speed imaging and optical emission spectroscopy were adopted to highlight the physical aspects of the in-liquid arc plasma jet system, and the feasibility of the system was investigated in a wastewater treatment case with phenol as the model contaminant. We found that the specific energy input is a reasonable parameter by which to characterize the overall process. The phenol removal reaction could be modeled as a pseudo-first-order reaction, and the reaction constant became smaller as the phenol concentration increased. However, complete decomposition of the phenol into water and carbon dioxide required very high energy because the final intermediate, oxalic acid, is relatively stable. Detailed chemical and physical analyses, including byproducts, ions, solution acidity, and conductivity, were conducted to evaluate this new method for use in the appropriate applications.

Study of dual radio frequency capacitively coupled plasma: an analytical treatment matched to an experiment

NASA Astrophysics Data System (ADS)

Saikia, P.; Bhuyan, H.; Escalona, M.; Favre, M.; Wyndham, E.; Maze, J.; Schulze, J.

2018-01-01

The behavior of a dual frequency capacitively coupled plasma (2f CCP) driven by 2.26 and 13.56 MHz radio frequency (rf) source is investigated using an approach that integrates a theoretical model and experimental data. The basis of the theoretical analysis is a time dependent dual frequency analytical sheath model that casts the relation between the instantaneous sheath potential and plasma parameters. The parameters used in the model are obtained by operating the 2f CCP experiment (2.26 MHz + 13.56 MHz) in argon at a working pressure of 50 mTorr. Experimentally measured plasma parameters such as the electron density, electron temperature, as well as the rf current density ratios are the inputs of the theoretical model. Subsequently, a convenient analytical solution for the output sheath potential and sheath thickness was derived. A comparison of the present numerical results is done with the results obtained in another 2f CCP experiment conducted by Semmler et al (2007 Plasma Sources Sci. Technol. 16 839). A good quantitative correspondence is obtained. The numerical solution shows the variation of sheath potential with the low and high frequency (HF) rf powers. In the low pressure plasma, the sheath potential is a qualitative measure of DC self-bias which in turn determines the ion energy. Thus, using this analytical model, the measured values of the DC self-bias as a function of low and HF rf powers are explained in detail.

Characterization and global modelling of low-pressure hydrogen-based RF plasmas suitable for surface cleaning processes

NASA Astrophysics Data System (ADS)

Škoro, Nikola; Puač, Nevena; Lazović, Saša; Cvelbar, Uroš; Kokkoris, George; Gogolides, Evangelos

2013-11-01

In this paper we present results of measurements and global modelling of low-pressure inductively coupled H2 plasma which is suitable for surface cleaning applications. The plasma is ignited at 1 Pa in a helicon-type reactor and is characterized using optical emission measurements (optical actinometry) and electrical measurements, namely Langmuir and catalytic probe. By comparing catalytic probe data obtained at the centre of the chamber with optical actinometry results, an approximate calibration of the actinometry method as a semi-quantititative measure of H density was achieved. Coefficients for conversion of actinometric ratios to H densities are tabulated and provided. The approximate validity region of the simple actinometry formula for low-pressure H2 plasma is discussed in the online supplementary data (stacks.iop.org/JPhysD/46/475206/mmedia). Best agreement with catalytic probe results was obtained for (Hβ, Ar750) and (Hβ, Ar811) actinometric line pairs. Additionally, concentrations of electrons and ions as well as plasma potential, electron temperature and ion fluxes were measured in the chamber centre at different plasma powers using a Langmuir probe. Moreover, a global model of an inductively coupled plasma was formulated using a compiled reaction set for H2/Ar gas mixture. The model results compared reasonably well with the results on H atom and charge particle densities and a sensitivity analysis of important input parameters was conducted. The influence of the surface recombination, ionization, and dissociation coefficients, and the ion-neutral collision cross-section on model results was demonstrated.

A power-balance model for local helicity injection startup in a spherical tokamak

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barr, Jayson L.; Bongard, Michael W.; Burke, Marcus G.

A 0D circuit model for predicting I p( t) in Local Helicity Injection (LHI) discharges is developed. Analytic formulas for estimating the surface flux of finite-A plasmas developed are modified and expanded to treat highly shaped, ultralow-A tokamak geometry using a database of representative equilibria. Model predictions are compared to sample LHI discharges in the A ~ 1 Pegasus spherical tokamak, and are found to agree within 15% of experimental I p( t). High performance LHI discharges are found to follow the Taylor relaxation current limit for approximately the first half of the current ramp, or I p ≲ 75more » kA. The second half of the current ramp follows a limit imposed by power-balance as plasmas expand from high- A to ultralow- A. Here, this shape evolution generates a significant drop in external plasma inductance, effectively using the plasma’s initially high inductance to drive the current ramp and provide > 70% of the current drive V-s. Projections using this model indicate the relative influences of higher helicity input rate and injector current on the attainable total plasma current.« less

A power-balance model for local helicity injection startup in a spherical tokamak

DOE PAGES

Barr, Jayson L.; Bongard, Michael W.; Burke, Marcus G.; ...

2018-05-15

A 0D circuit model for predicting I p( t) in Local Helicity Injection (LHI) discharges is developed. Analytic formulas for estimating the surface flux of finite-A plasmas developed are modified and expanded to treat highly shaped, ultralow-A tokamak geometry using a database of representative equilibria. Model predictions are compared to sample LHI discharges in the A ~ 1 Pegasus spherical tokamak, and are found to agree within 15% of experimental I p( t). High performance LHI discharges are found to follow the Taylor relaxation current limit for approximately the first half of the current ramp, or I p ≲ 75more » kA. The second half of the current ramp follows a limit imposed by power-balance as plasmas expand from high- A to ultralow- A. Here, this shape evolution generates a significant drop in external plasma inductance, effectively using the plasma’s initially high inductance to drive the current ramp and provide > 70% of the current drive V-s. Projections using this model indicate the relative influences of higher helicity input rate and injector current on the attainable total plasma current.« less

Double-input compartmental modeling and spectral analysis for the quantification of positron emission tomography data in oncology.

PubMed

Tomasi, G; Kimberley, S; Rosso, L; Aboagye, E; Turkheimer, F

2012-04-07

In positron emission tomography (PET) studies involving organs different from the brain, ignoring the metabolite contribution to the tissue time-activity curves (TAC), as in the standard single-input (SI) models, may compromise the accuracy of the estimated parameters. We employed here double-input (DI) compartmental modeling (CM), previously used for [¹¹C]thymidine, and a novel DI spectral analysis (SA) approach on the tracers 5-[¹⁸F]fluorouracil (5-[¹⁸F]FU) and [¹⁸F]fluorothymidine ([¹⁸F]FLT). CM and SA were performed initially with a SI approach using the parent plasma TAC as an input function. These methods were then employed using a DI approach with the metabolite plasma TAC as an additional input function. Regions of interest (ROIs) corresponding to healthy liver, kidneys and liver metastases for 5-[¹⁸F]FU and to tumor, vertebra and liver for [¹⁸F]FLT were analyzed. For 5-[¹⁸F]FU, the improvement of the fit quality with the DI approaches was remarkable; in CM, the Akaike information criterion (AIC) always selected the DI over the SI model. Volume of distribution estimates obtained with DI CM and DI SA were in excellent agreement, for both parent 5-[¹⁸F]FU (R(2) = 0.91) and metabolite [¹⁸F]FBAL (R(2) = 0.99). For [¹⁸F]FLT, the DI methods provided notable improvements but less substantial than for 5-[¹⁸F]FU due to the lower rate of metabolism of [¹⁸F]FLT. On the basis of the AIC values, agreement between [¹⁸F]FLT K(i) estimated with the SI and DI models was good (R² = 0.75) for the ROIs where the metabolite contribution was negligible, indicating that the additional input did not bias the parent tracer only-related estimates. When the AIC suggested a substantial contribution of the metabolite [¹⁸F]FLT-glucuronide, on the other hand, the change in the parent tracer only-related parameters was significant (R² = 0.33 for K(i)). Our results indicated that improvements of DI over SI approaches can range from moderate to substantial and are more significant for tracers with a high rate of metabolism. Furthermore, they showed that SA is suitable for DI modeling and can be used effectively in the analysis of PET data.

Modeling of helicon wave propagation and the physical process of helicon plasma production

NASA Astrophysics Data System (ADS)

Isayama, Shogo; Hada, Tohru; Shinohara, Shunjiro; Tanikawa, Takao

2014-10-01

Helicon plasma is a high-density and low-temperature plasma generated by the helicon wave, and is expected to be useful for various applications. On the other hand, there still remain a number of unsolved physical issues regarding how the plasma is generated using the helicon wave. The generation involves such physical processes as wave propagation, mode conversion, and collisionless as well as collisional wave damping that leads to ionization/recombination of neutral particles. In this study, we attempt to construct a model for the helicon plasma production using numerical simulations. In particular, we will make a quantitative argument on the roles of the mode conversion from the helicon to the electrostatic Trivelpiece-Gould (TG) wave, as first proposed by Shamrai. According to his scenario, the long wavelength helicon wave linearly mode converts to the TG wave, which then dissipates rapidly due to its large wave number. On the other hand, the efficiency of the mode conversion depends strongly on the magnitudes of dissipation parameters. Particularly when the dissipation is dominant, the TG wave is no longer excited and the input helicon wave directly dissipates. In the presentation, we will discuss the mode conversion and the plasma heating using numerical simulations.

New method for rekindling the nonlinear solitary waves in Maxwellian complex space plasma

NASA Astrophysics Data System (ADS)

Das, G. C.; Sarma, Ridip

2018-04-01

Our interest is to study the nonlinear wave phenomena in complex plasma constituents with Maxwellian electrons and ions. The main reason for this consideration is to exhibit the effects of dust charge fluctuations on acoustic modes evaluated by the use of a new method. A special method (G'/G) has been developed to yield the coherent features of nonlinear waves augmented through the derivation of a Korteweg-de Vries equation and found successfully the different nature of solitons recognized in space plasmas. Evolutions have shown with the input of appropriate typical plasma parameters to support our theoretical observations in space plasmas. All conclusions are in good accordance with the actual occurrences and could be of interest to further the investigations in experiments and satellite observations in space. In this paper, we present not only the model that exhibited nonlinear solitary wave propagation but also a new mathematical method to the execution.

Fast 2D fluid-analytical simulation of ion energy distributions and electromagnetic effects in multi-frequency capacitive discharges

NASA Astrophysics Data System (ADS)

Kawamura, E.; Lieberman, M. A.; Graves, D. B.

2014-12-01

A fast 2D axisymmetric fluid-analytical plasma reactor model using the finite elements simulation tool COMSOL is interfaced with a 1D particle-in-cell (PIC) code to study ion energy distributions (IEDs) in multi-frequency capacitive argon discharges. A bulk fluid plasma model, which solves the time-dependent plasma fluid equations for the ion continuity and electron energy balance, is coupled with an analytical sheath model, which solves for the sheath parameters. The time-independent Helmholtz equation is used to solve for the fields and a gas flow model solves for the steady-state pressure, temperature and velocity of the neutrals. The results of the fluid-analytical model are used as inputs to a PIC simulation of the sheath region of the discharge to obtain the IEDs at the target electrode. Each 2D fluid-analytical-PIC simulation on a moderate 2.2 GHz CPU workstation with 8 GB of memory took about 15-20 min. The multi-frequency 2D fluid-analytical model was compared to 1D PIC simulations of a symmetric parallel-plate discharge, showing good agreement. We also conducted fluid-analytical simulations of a multi-frequency argon capacitively coupled plasma (CCP) with a typical asymmetric reactor geometry at 2/60/162 MHz. The low frequency 2 MHz power controlled the sheath width and sheath voltage while the high frequencies controlled the plasma production. A standing wave was observable at the highest frequency of 162 MHz. We noticed that adding 2 MHz power to a 60 MHz discharge or 162 MHz to a dual frequency 2 MHz/60 MHz discharge can enhance the plasma uniformity. We found that multiple frequencies were not only useful for controlling IEDs but also plasma uniformity in CCP reactors.

Statistical validation of predictive TRANSP simulations of baseline discharges in preparation for extrapolation to JET D-T

NASA Astrophysics Data System (ADS)

Kim, Hyun-Tae; Romanelli, M.; Yuan, X.; Kaye, S.; Sips, A. C. C.; Frassinetti, L.; Buchanan, J.; Contributors, JET

2017-06-01

This paper presents for the first time a statistical validation of predictive TRANSP simulations of plasma temperature using two transport models, GLF23 and TGLF, over a database of 80 baseline H-mode discharges in JET-ILW. While the accuracy of the predicted T e with TRANSP-GLF23 is affected by plasma collisionality, the dependency of predictions on collisionality is less significant when using TRANSP-TGLF, indicating that the latter model has a broader applicability across plasma regimes. TRANSP-TGLF also shows a good matching of predicted T i with experimental measurements allowing for a more accurate prediction of the neutron yields. The impact of input data and assumptions prescribed in the simulations are also investigated in this paper. The statistical validation and the assessment of uncertainty level in predictive TRANSP simulations for JET-ILW-DD will constitute the basis for the extrapolation to JET-ILW-DT experiments.

Experimental investigation and numerical modelling of positive corona discharge: ozone generation

NASA Astrophysics Data System (ADS)

Yanallah, K; Pontiga, F; Fernández-Rueda, A; Castellanos, A

2009-03-01

The spatial distribution of the species generated in a wire-cylinder positive corona discharge in pure oxygen has been computed using a plasma chemistry model that includes the most significant reactions between electrons, ions, atoms and molecules. The plasma chemistry model is included in the continuity equations of each species, which are coupled with Poisson's equation for the electric field and the energy conservation equation for the gas temperature. The current-voltage characteristic measured in the experiments has been used as an input data to the numerical simulation. The numerical model is able to reproduce the basic structure of the positive corona discharge and highlights the importance of Joule heating on ozone generation. The average ozone density has been computed as a function of current intensity and compared with the experimental measurements of ozone concentration determined by UV absorption spectroscopy.

Feature Profile Evolution of SiO2 Trenches In Fluorocarbon Plasmas

NASA Technical Reports Server (NTRS)

Hwang, Helen; Govindan, T. R.; Meyyappan, M.; Arunachalam, Valli; Rauf, Shahid; Coronell, Dan; Carroll, Carol W. (Technical Monitor)

1999-01-01

Etching of silicon microstructures for semiconductor manufacturing in chlorine plasmas has been well characterized. The etching proceeds in a two-part process, where the chlorine neutrals passivate the Si surface and then the ions etch away SiClx. However, etching in more complicated gas mixtures and materials, such as etching of SiO2 in Ar/C4F8, requires knowledge of the ion and neutral distribution functions as a function of angle and velocity, in addition to modeling the gas surface reactions. In order to address these needs, we have developed and integrated a suite of models to simulate the etching process from the plasma reactor level to the feature profile evolution level. This arrangement allows for a better understanding, control, and prediction of the influence of equipment level process parameters on feature profile evolution. We are currently using the HPEM (Hybrid Plasma Equipment Model) and PCMCM (Plasma Chemistry Monte Carlo Model) to generate plasma properties and ion and neutral distribution functions for argon/fluorocarbon discharges in a GEC Reference Cell. These quantities are then input to the feature scale model, Simulation of Profile Evolution by Level Sets (SPELS). A surface chemistry model is used to determine the interaction of the incoming species with the substrate material and simulate the evolution of the trench profile. The impact of change of gas pressure and inductive power on the relative flux of CFx and F to the wafer, the etch and polymerization rates, and feature profiles will be examined. Comparisons to experimental profiles will also be presented.

Towards a Predictive Capability for Local Helicity Injection Startup

NASA Astrophysics Data System (ADS)

Barr, J. L.; Bongard, M. W.; Burke, M. G.; Fonck, R. J.; Hinson, E. T.; Lewicki, B. T.; Perry, J. M.; Redd, A. J.; Schlossberg, D. J.

2014-10-01

Local helicity injection (LHI) is a non-solenoidal tokamak startup technique under development on the Pegasus ST. New designs of the injector cathode geometry and plasma-facing shield rings support high-voltage operation up to 1.5 kV. This leads to reduced requirements in injector area for a given helicity input rate. Near-term experiments in Pegasus are testing the gain in Ip obtained with a 1 . 5 × increase in the helicity input rate and the efficacy of helicity injection in the lower divertor region. A predictive model for LHI is needed to project scalable scenarios for larger devices. A lumped-parameter circuit model using power and helicity balance is being developed for LHI on Pegasus-U and NSTX-U. The model indicates that MA-class startup on NSTX-U will require operating in a regime where the drive from LHI dominates the inductive effects arising from dynamically evolving plasma geometry. The physics of this new regime can be tested in Pegasus-U at Ip ~ 0 . 3 MA. The LHI systems on the proposed Pegasus-U will be expanded to provide 3 - 4 × helicity injection rate and the toroidal field doubled to reach this regime. Predictive models to be validated on Pegasus-U include the 0-D power balance model, NIMROD, and TSC. Work supported by US DOE Grants DE-FG02-96ER54375 and DE-SC0006928.

Advanced Hybrid Modeling of Hall Thruster Plumes

DTIC Science & Technology

2010-06-16

Hall thruster operated in the Large Vacuum Test Facility at the University of Michigan. The approach utilizes the direct simulation Monte Carlo method and the Particle-in-Cell method to simulate the collision and plasma dynamics of xenon neutrals and ions. The electrons are modeled as a fluid using conservation equations. A second code is employed to model discharge chamber behavior to provide improved input conditions at the thruster exit for the plume simulation. Simulation accuracy is assessed using experimental data previously

Studies to Improve the Science in the GAIM - Full Physics Model

DTIC Science & Technology

2014-01-01

Hromsco, J. J., Sensitivity of IFM /GAIM-GM Model to High Cadence Kp and F10.7 Input, Utah State University/Air Force Institute of Technology, M . S ...Institute of Technology, M . S . Thesis; March, 2011. Nava, O. A ., Analysis of plasma bubble signatures in the ionosphere, Utah State University/Air...Force Institute of Technology, M . S . Thesis; March, 2011. Scherliess, L., R. W. Schunk and D. C. Thompson, Data assimilation models: A ’new’ tool for

ARC length control for plasma welding

NASA Technical Reports Server (NTRS)

Iceland, William F. (Inventor)

1988-01-01

A control system to be used with a plasma arc welding apparatus is disclosed. The plasma arc welding apparatus includes a plasma arc power supply, a contactor, and an electrode assembly for moving the electrode relative to a work piece. The electrode assembly is raised or lowered by a drive motor. The present apparatus includes a plasma arc adapter connected across the power supply to measure the voltage across the plasma arc. The plasma arc adapter forms a dc output signal input to a differential amplifier. A second input is defined by an adjustable resistor connected to a dc voltage supply to permit operator control. The differential amplifier forms an output difference signal provided to an adder circuit. The adder circuit then connects with a power amplifier which forms the driving signal for the motor. In addition, the motor connects to a tachometor which forms a feedback signal delivered to the adder to provide damping, therby avoiding servo loop overshoot.

Correlation between the plasma characteristics and the surface chemistry of plasma-treated polymers through partial least-squares analysis.

PubMed

Mavadat, Maryam; Ghasemzadeh-Barvarz, Massoud; Turgeon, Stéphane; Duchesne, Carl; Laroche, Gaétan

2013-12-23

We investigated the effect of various plasma parameters (relative density of atomic N and H, plasma temperature, and vibrational temperature) and process conditions (pressure and H2/(N2 + H2) ratio) on the chemical composition of modified poly(tetrafluoroethylene) (PTFE). The plasma parameters were measured by means of near-infrared (NIR) and UV-visible emission spectroscopy with and without actinometry. The process conditions of the N2-H2 microwave discharges were set at various pressures ranging from 100 to 2000 mTorr and H2/(N2+H2) gas mixture ratios between 0 and 0.4. The surface chemical composition of the modified polymers was determined by X-ray photoelectron spectroscopy (XPS). A mathematical model was constructed using the partial least-squares regression algorithm to correlate the plasma information (process condition and plasma parameters as determined by emission spectroscopy) with the modified surface characteristics. To construct the model, a set of data input variables containing process conditions and plasma parameters were generated, as well as a response matrix containing the surface composition of the polymer. This model was used to predict the composition of PTFE surfaces subjected to N2-H2 plasma treatment. Contrary to what is generally accepted in the literature, the present data demonstrate that hydrogen is not directly involved in the defluorination of the surface but rather produces atomic nitrogen and/or NH radicals that are shown to be at the origin of fluorine atom removal from the polymer surface. The results show that process conditions alone do not suffice in predicting the surface chemical composition and that the plasma characteristics, which cannot be easily correlated with these conditions, should be considered. Process optimization and control would benefit from plasma diagnostics, particularly infrared emission spectroscopy.

Dissipated power and induced velocity fields data of a micro single dielectric barrier discharge plasma actuator for active flow control☆

PubMed Central

Pescini, E.; Martínez, D.S.; De Giorgi, M.G.; Francioso, L.; Ficarella, A.

2015-01-01

In recent years, single dielectric barrier discharge (SDBD) plasma actuators have gained great interest among all the active flow control devices typically employed in aerospace and turbomachinery applications [1,2]. Compared with the macro SDBDs, the micro single dielectric barrier discharge (MSDBD) actuators showed a higher efficiency in conversion of input electrical power to delivered mechanical power [3,4]. This article provides data regarding the performances of a MSDBD plasma actuator [5,6]. The power dissipation values [5] and the experimental and numerical induced velocity fields [6] are provided. The present data support and enrich the research article entitled “Optimization of micro single dielectric barrier discharge plasma actuator models based on experimental velocity and body force fields” by Pescini et al. [6]. PMID:26425667

Fast 2D Fluid-Analytical Simulation of IEDs and Plasma Uniformity in Multi-frequency CCPs

NASA Astrophysics Data System (ADS)

Kawamura, E.; Lieberman, M. A.; Graves, D. B.

2014-10-01

A fast 2D axisymmetric fluid-analytical model using the finite elements tool COMSOL is interfaced with a 1D particle-in-cell (PIC) code to study ion energy distributions (IEDs) in multi-frequency argon capacitively coupled plasmas (CCPs). A bulk fluid plasma model which solves the time-dependent plasma fluid equations is coupled with an analytical sheath model which solves for the sheath parameters. The fluid-analytical results are used as input to a PIC simulation of the sheath region of the discharge to obtain the IEDs at the wafer electrode. Each fluid-analytical-PIC simulation on a moderate 2.2 GHz CPU workstation with 8 GB of memory took about 15-20 minutes. The 2D multi-frequency fluid-analytical model was compared to 1D PIC simulations of a symmetric parallel plate discharge, showing good agreement. Fluid-analytical simulations of a 2/60/162 MHz argon CCP with a typical asymmetric reactor geometry were also conducted. The low 2 MHz frequency controlled the sheath width and voltage while the higher frequencies controlled the plasma production. A standing wave was observable at the highest frequency of 162 MHz. Adding 2 MHz power to a 60 MHz discharge or 162 MHz to a dual frequency 2 MHz/60 MHz discharge enhanced the plasma uniformity. This work was supported by the Department of Energy Office of Fusion Energy Science Contract DE-SC000193, and in part by gifts from Lam Research Corporation and Micron Corporation.

In vivo metabolism and partitioning of 6-[18F]fluoro-L-meta-tyrosine in whole blood: a unified compartment model

NASA Astrophysics Data System (ADS)

Asselin, Marie-Claude; Wahl, Lindi M.; Cunningham, Vincent J.; Amano, Shigeko; Nahmias, Claude

2002-06-01

Physiological quantification of dynamic PET data requires the determination of an input function, preferably from plasma. A compartmental model relating a parent radiotracer, its radiolabelled metabolites and their exchange between plasma and erythrocytes is presented. This model allows for the time course of radioactivity measured in whole blood to be transformed into the time course of the radiotracer in plasma. The utility of this approach is illustrated with blood data collected on 30 human subjects injected with 6-[18F]fluoro-L-meta-tyrosine (FmT), a pre-synaptic dopaminergic radiotracer. A three-compartment four-parameter model is shown to yield significantly better fits to the blood data than related lower and higher order models. This model is found to be robust to measurement noise, and yet sensitive to metabolic changes induced by pretreatment with carbidopa. For FmT, the between-subject variations are shown to be small enough to warrant the use of a population-based correction;; tissue time-activity curves were simulated to verify that this correction does not significantly affect the precision and accuracy of the derived rate constants. The unified blood model can be adapted for radiotracers other than FmT as long as the blood partition ratio of the parent radiotracer differs from that of its metabolites and/or the rate at which they equilibrate between plasma and erythrocytes is different.

Modelling of plasma-based dry reforming: how do uncertainties in the input data affect the calculation results?

NASA Astrophysics Data System (ADS)

Wang, Weizong; Berthelot, Antonin; Zhang, Quanzhi; Bogaerts, Annemie

2018-05-01

One of the main issues in plasma chemistry modeling is that the cross sections and rate coefficients are subject to uncertainties, which yields uncertainties in the modeling results and hence hinders the predictive capabilities. In this paper, we reveal the impact of these uncertainties on the model predictions of plasma-based dry reforming in a dielectric barrier discharge. For this purpose, we performed a detailed uncertainty analysis and sensitivity study. 2000 different combinations of rate coefficients, based on the uncertainty from a log-normal distribution, are used to predict the uncertainties in the model output. The uncertainties in the electron density and electron temperature are around 11% and 8% at the maximum of the power deposition for a 70% confidence level. Still, this can have a major effect on the electron impact rates and hence on the calculated conversions of CO2 and CH4, as well as on the selectivities of CO and H2. For the CO2 and CH4 conversion, we obtain uncertainties of 24% and 33%, respectively. For the CO and H2 selectivity, the corresponding uncertainties are 28% and 14%, respectively. We also identify which reactions contribute most to the uncertainty in the model predictions. In order to improve the accuracy and reliability of plasma chemistry models, we recommend using only verified rate coefficients, and we point out the need for dedicated verification experiments.

Transport Simulations of DIII-D Discharges with Impurity Injection

NASA Astrophysics Data System (ADS)

Mandrekas, J.; Stacey, W. M.; Murakami, M.

2001-10-01

Several recent DIII-D discharges with external impurity injection into L-mode plasmas are analyzed with a coupled main plasma and multi-charge state 1frac 12-D impurity transport code. These discharges exhibit various degrees of confinement improvement, which has been attributed to the synergistic effects of impurity induced enhancement of the E×B shearing rate and reduction of the drift wave turbulence growth rate (M. Murakami, et. al., Nucl. Fusion 41) (2001) 317.. Impurity transport is described by empirical and neoclassical transport models. Both the standard neoclassical theory as well as an enhanced theory which takes into account the effects of external momentum input and radial momentum transport (W.M. Stacey, Phys. Plasmas 8) (2001) 158. have been considered.

Plasma property and performance prediction for mercury ion thrusters

NASA Technical Reports Server (NTRS)

Longhurst, G. R.; Wilbur, P. J.

1979-01-01

The discharge chambers of mercury ion thrusters are modelled so the principal effects and processes which govern discharge plasma properties and thruster performance are described. The conservation relations for mass, charge and energy when applied to the Maxwellian electron population in the ion production region yield equations which may be made one-dimensional by the proper choice of coordinates. Solutions to these equations with the appropriate boundary conditions give electron density and temperature profiles which agree reasonably well with measurements. It is then possible to estimate plasma properties from thruster design data and those operating parameters which are directly controllable. By varying the operating parameter inputs to the computer code written to solve these equations, perfromance curves are obtained which agree quite well with measurements.

Pharmacokinetics of plasma enfuvirtide after subcutaneous administration to patients with human immunodeficiency virus: Inverse Gaussian density absorption and 2-compartment disposition.

PubMed

Zhang, Xiaoping; Nieforth, Keith; Lang, Jean-Marie; Rouzier-Panis, Regine; Reynes, Jacques; Dorr, Albert; Kolis, Stanley; Stiles, Mark R; Kinchelow, Tosca; Patel, Indravadan H

2002-07-01

Enfuvirtide (T-20) is the first of a novel class of human immunodeficiency virus (HIV) drugs that block gp41-mediated viral fusion to host cells. The objectives of this study were to develop a structural pharmacokinetic model that would adequately characterize the absorption and disposition of enfuvirtide pharmacokinetics after both intravenous and subcutaneous administration and to evaluate the dose proportionality of enfuvirtide pharmacokinetic parameters at a subcutaneous dose higher than that currently used in phase III studies. Twelve patients with HIV infection received 4 single doses of enfuvirtide separated by a 1-week washout period in an open-label, randomized, 4-way crossover fashion. The doses studied were 90 mg (intravenous) and 45 mg, 90 mg, and 180 mg (subcutaneous). Serial blood samples were collected up to 48 hours after each dose. Plasma enfuvirtide concentrations were measured with use of a validated liquid chromatography-tandem mass spectrometry method. Enfuvirtide plasma concentration-time data after subcutaneous administration were well described by an inverse Gaussian density function-input model linked to a 2-compartment open distribution model with first-order elimination from the central compartment. The model-derived mean pharmacokinetic parameters (+/-SD) were volume of distribution of the central compartment (3.8 +/- 0.8 L), volume of distribution of the peripheral compartment (1.7 +/- 0.6 L), total clearance (1.44 +/- 0.30 L/h), intercompartmental distribution (2.3 +/- 1.1 L/h), bioavailability (89% +/- 11%), and mean absorption time (7.26 hours, 8.65 hours, and 9.79 hours for the 45-mg, 90-mg, and 180-mg dose groups, respectively). The terminal half-life increased from 3.46 to 4.35 hours for the subcutaneous dose range from 45 to 180 mg. An inverse Gaussian density function-input model linked to a 2-compartment open distribution model with first-order elimination from the central compartment was appropriate to describe complex absorption and disposition kinetics of enfuvirtide plasma concentration-time data after subcutaneous administration to patients with HIV infection. Enfuvirtide was nearly completely absorbed from subcutaneous depot, and pharmacokinetic parameters were linear up to a dose of 180 mg in this study.

Modelling of fluid flow phenomenon in laser+GMAW hybrid welding of aluminum alloy considering three phase coupling and arc plasma shear stress

NASA Astrophysics Data System (ADS)

Xu, Guoxiang; Li, Pengfei; Cao, Qingnan; Hu, Qingxian; Gu, Xiaoyan; Du, Baoshuai

2018-03-01

The present study aims to develop a unified three dimensional numerical model for fiber laser+GMAW hybrid welding, which is used to study the fluid flow phenomena in hybrid welding of aluminum alloy and the influence of laser power on weld pool dynamic behavior. This model takes into account the coupling of gas, liquid and metal phases. Laser heat input is described using a cone heat source model with changing peak power density, its height being determined based on the keyhole size. Arc heat input is modeled as a double ellipsoid heat source. The arc plasma flow and droplet transfer are simulated through the two simplified models. The temperature and velocity fields for different laser powers are calculated. The computed results are in general agreement with the experimental data. Both the peak and average values of fluid flow velocity during hybrid welding are much higher than those of GMAW. At a low level of laser power, both the arc force and droplet impingement force play a relatively large role on fluid flow in the hybrid welding. Keyhole depth always oscillates within a range. With an increase in laser power, the weld pool behavior becomes more complex. An anti-clockwise vortex is generated and the stability of keyhole depth is improved. Besides, the effects of laser power on different driving forces of fluid flow in weld pool are also discussed.

Comparison of Global Martian Plasma Models in the Context of MAVEN Observations

NASA Astrophysics Data System (ADS)

Egan, Hilary; Ma, Yingjuan; Dong, Chuanfei; Modolo, Ronan; Jarvinen, Riku; Bougher, Stephen; Halekas, Jasper; Brain, David; Mcfadden, James; Connerney, John; Mitchell, David; Jakosky, Bruce

2018-05-01

Global models of the interaction of the solar wind with the Martian upper atmosphere have proved to be valuable tools for investigating both the escape to space of the Martian atmosphere and the physical processes controlling this complex interaction. The many models currently in use employ different physical assumptions, but it can be difficult to directly compare the effectiveness of the models since they are rarely run for the same input conditions. Here we present the results of a model comparison activity, where five global models (single-fluid MHD, multifluid MHD, multifluid electron pressure MHD, and two hybrid models) were run for identical conditions corresponding to a single orbit of observations from the Mars Atmosphere and Volatile EvolutioN (MAVEN) spacecraft. We find that low-altitude ion densities are very similar across all models and are comparable to MAVEN ion density measurements from periapsis. Plasma boundaries appear generally symmetric in all models and vary only slightly in extent. Despite these similarities there are clear morphological differences in ion behavior in other regions such as the tail and southern hemisphere. These differences are observable in ion escape loss maps and are necessary to understand in order to accurately use models in aiding our understanding of the Martian plasma environment.

Hall-MHD and PIC Modeling of the Conduction-to-Opening Transition in a Plasma Opening Switch

NASA Astrophysics Data System (ADS)

Schumer, J. W.; SwanekampDdagger, S. B.; Ottinger, P. F.; Commisso, R. J.; Weber, B. V.

1998-11-01

Utilizing the fast opening characteristics of a plasma opening switch (POS), inductive energy storage devices can generate short-duration high-power pulses (<0.1 μ s, >1 TW) with current rise-times on the order of 10 ns. Plasma redistribution and thinning during the POS conduction phase can be modeled adequately with MHD methods. By including the Hall term in Ohm's Law, MHD methods can simulate plasmas with density gradient scale lengths between c/ω_pe < Ln < c/ω_pi. However, the neglect of electron inertia (c/ω_pe) and space-charge separation (λ_De) by single-fluid theory eventually becomes invalid in small gap regions that form during POS opening. PIC methods are well-suited for low-density plasmas, but are numerically taxed by high-density POS regions. An interface converts MHD (Mach2) output into PIC (Magic) input suitable for validating various transition criteria through comparison of current and density distributions from both methods. We will discuss recent progress in interfacing Hall-MHD and PIC simulations. Work supported by Defense Special Weapons Agency. ^ NRL-NRC Research Associate. hspace0.25in ^ JAYCOR, Vienna, VA 22102.

The Electrical Structure of Discharges Modified by Electron Beams

NASA Astrophysics Data System (ADS)

Haas, F. A.; Braithwaite, N. St. J.

1997-10-01

Injection of an electron beam into a low pressure plasma modifies both the electrical structure and the distributions of charged particle energies. The electrical structure is investigated here in a one-dimensional model by representing the discharge as two collisionless sheaths with a monenergetic electron beam, linked by a quasi-neutral collisional region. The latter is modelled by fluid equations in which the beam current decreases with position. Since the electrodes are connected by an external conductor this implies through Kirchoff's laws that the thermal electron current must correspondingly increase with position. Given the boundary conditions and beam input at the first electrode then the rest of the system is uniquely described. The model reveals the dependence of the sheath potentials at the emitting and absorbing surfaces on the beam current. The model is relevant to externally injected beams and to electron beams originating from secondary processes on surfaces exposed to the plasma.

Two Temperature Modeling and Experimental Measurements of Laser Sustained Hydrogen Plasmas

DTIC Science & Technology

1993-05-01

4 1.3 Theoretical Background .................................................................. 7 1.4...typically produce low specific impulses with an upper limit of approximately 450 seconds. The theoretical chamber temperature in such a system can be as...systems are theoretically capable of producing moderate thrusts (> 1 kN) with specific impulses in excess of 1000 seconds for 10 MW input power. This

NEURAL NETWORK INTERACTIONS AND INGESTIVE BEHAVIOR CONTROL DURING ANOREXIA

PubMed Central

Watts, Alan G.; Salter, Dawna S.; Neuner, Christina M.

2007-01-01

Many models have been proposed over the years to explain how motivated feeding behavior is controlled. One of the most compelling is based on the original concepts of Eliot Stellar whereby sets of interosensory and exterosensory inputs converge on a hypothalamic control network that can either stimulate or inhibit feeding. These inputs arise from information originating in the blood, the viscera, and the telencephalon. In this manner the relative strengths of the hypothalamic stimulatory and inhibitory networks at a particular time dictates how an animal feeds. Anorexia occurs when the balance within the networks consistently favors the restraint of feeding. This article discusses experimental evidence supporting a model whereby the increases in plasma osmolality that result from drinking hypertonic saline activate pathways projecting to neurons in the paraventricular nucleus of the hypothalamus (PVH) and lateral hypothalamic area (LHA). These neurons constitute the hypothalamic controller for ingestive behavior, and receive a set of afferent inputs from regions of the brain that process sensory information that is critical for different aspects of feeding. Important sets of inputs arise in the arcuate nucleus, the hindbrain, and in the telencephalon. Anorexia is generated in dehydrated animals by way of osmosensitive projections to the behavior control neurons in the PVH and LHA, rather than by actions on their afferent inputs. PMID:17531275

ELM Mitigation in Low-rotation ITER Baseline Scenario Plasmas on DIII-D with Deuterium Pellet Injection

NASA Astrophysics Data System (ADS)

Baylor, L. R.

2016-10-01

ELM mitigation using high frequency D2 pellet ELM pacing has been demonstrated in ITER baseline scenario plasmas on DIII D with low rotation obtained with low NBI input torque. The ITER burning plasmas will have relatively low input torque and are expected to have low rotation. ELM mitigation by on-demand pellet ELM triggering has not been observed before in these conditions. New experiments on DIII-D in these conditions with 90 Hz D2 pellets have shown that significant mitigation of the divertor ELM peak heat flux by a factor of 8 is possible without detrimental effects to the plasma confinement. High-Z impurity accumulation is dramatically reduced at all input torques from 0.1 to 2.5 N-m. Fueling with high field side injection of D2 pellets has been employed to demonstrate that density buildup can be obtained simultaneously with ELM mitigation. The implications are that rapid pellet injection remains a promising technique to trigger on-demand ELMs in low rotating plasmas with greatly reduced peak flux while preventing impurity accumulation in ITER. Supported by the US DOE under DE-AC05-00OR22725, DE-FC02-04ER54698.

Recombination emissions and spectral blueshift of pump radiation from ultrafast laser induced plasma in a planar water microjet

NASA Astrophysics Data System (ADS)

Anija, M.; Philip, Reji

2009-09-01

We report spectroscopic investigations of an ultrafast laser induced plasma generated in a planar water microjet. Plasma recombination emissions along with the spectral blueshift and broadening of the pump laser pulse contribute to the total emission. The laser pulses are of 100 fs duration, and the incident intensity is around 10 15 W/cm 2. The dominant mechanisms leading to plasma formation are optical tunnel ionization and collisional ionization. Spectrally resolved polarization measurements show that the high frequency region of the emission is unpolarized whereas the low frequency region is polarized. Results indicate that at lower input intensities the emission arises mainly from plasma recombinations, which is accompanied by a weak blueshift of the incident laser pulse. At higher input intensities strong recombination emissions are seen, along with a broadening and asymmetric spectral blueshift of the pump laser pulse. From the nature of the blueshifted laser pulse it is possible to deduce whether the rate of change of free electron density is a constant or variable within the pulse lifetime. Two input laser intensity regimes, in which collisional and tunnel ionizations are dominant respectively, have been thus identified.

Empirical Modeling of the Plasmasphere Dynamics Using Neural Networks

NASA Astrophysics Data System (ADS)

Zhelavskaya, I. S.; Shprits, Y.; Spasojevic, M.

2017-12-01

We present a new empirical model for reconstructing the global dynamics of the cold plasma density distribution based only on solar wind data and geomagnetic indices. Utilizing the density database obtained using the NURD (Neural-network-based Upper hybrid Resonance Determination) algorithm for the period of October 1, 2012 - July 1, 2016, in conjunction with solar wind data and geomagnetic indices, we develop a neural network model that is capable of globally reconstructing the dynamics of the cold plasma density distribution for 2 ≤ L ≤ 6 and all local times. We validate and test the model by measuring its performance on independent datasets withheld from the training set and by comparing the model predicted global evolution with global images of He+ distribution in the Earth's plasmasphere from the IMAGE Extreme UltraViolet (EUV) instrument. We identify the parameters that best quantify the plasmasphere dynamics by training and comparing multiple neural networks with different combinations of input parameters (geomagnetic indices, solar wind data, and different durations of their time history). We demonstrate results of both local and global plasma density reconstruction. This study illustrates how global dynamics can be reconstructed from local in-situ observations by using machine learning techniques.

Exploring the plasma chemistry in microwave chemical vapor deposition of diamond from C/H/O gas mixtures.

PubMed

Kelly, Mark W; Richley, James C; Western, Colin M; Ashfold, Michael N R; Mankelevich, Yuri A

2012-09-27

Microwave (MW)-activated CH(4)/CO(2)/H(2) gas mixtures operating under conditions relevant to diamond chemical vapor deposition (i.e., X(C/Σ) = X(elem)(C)/(X(elem)(C) + X(elem)(O)) ≈ 0.5, H(2) mole fraction = 0.3, pressure, p = 150 Torr, and input power, P = 1 kW) have been explored in detail by a combination of spatially resolved absorption measurements (of CH, C(2)(a), and OH radicals and H(n = 2) atoms) within the hot plasma region and companion 2-dimensional modeling of the plasma. CO and H(2) are identified as the dominant species in the plasma core. The lower thermal conductivity of such a mixture (cf. the H(2)-rich plasmas used in most diamond chemical vapor deposition) accounts for the finding that CH(4)/CO(2)/H(2) plasmas can yield similar maximal gas temperatures and diamond growth rates at lower input powers than traditional CH(4)/H(2) plasmas. The plasma chemistry and composition is seen to switch upon changing from oxygen-rich (X(C/Σ) < 0.5) to carbon-rich (X(C/Σ) > 0.5) source gas mixtures and, by comparing CH(4)/CO(2)/H(2) (X(C/Σ) = 0.5) and CO/H(2) plasmas, to be sensitive to the choice of source gas (by virtue of the different prevailing gas activation mechanisms), in contrast to C/H process gas mixtures. CH(3) radicals are identified as the most abundant C(1)H(x) [x = 0-3] species near the growing diamond surface within the process window for successful diamond growth (X(C/Σ) ≈ 0.5-0.54) identified by Bachmann et al. (Diamond Relat. Mater.1991, 1, 1). This, and the findings of similar maximal gas temperatures (T(gas) ~2800-3000 K) and H atom mole fractions (X(H)~5-10%) to those found in MW-activated C/H plasmas, points to the prevalence of similar CH(3) radical based diamond growth mechanisms in both C/H and C/H/O plasmas.

Drug Delivery and Transport into the Central Circulation: An Example of Zero-Order In vivo Absorption of Rotigotine from a Transdermal Patch Formulation.

PubMed

Cawello, Willi; Braun, Marina; Andreas, Jens-Otto

2018-01-13

Pharmacokinetic studies using deconvolution methods and non-compartmental analysis to model clinical absorption of drugs are not well represented in the literature. The purpose of this research was (1) to define the system of equations for description of rotigotine (a dopamine receptor agonist delivered via a transdermal patch) absorption based on a pharmacokinetic model and (2) to describe the kinetics of rotigotine disposition after single and multiple dosing. The kinetics of drug disposition was evaluated based on rotigotine plasma concentration data from three phase 1 trials. In two trials, rotigotine was administered via a single patch over 24 h in healthy subjects. In a third trial, rotigotine was administered once daily over 1 month in subjects with early-stage Parkinson's disease (PD). A pharmacokinetic model utilizing deconvolution methods was developed to describe the relationship between drug release from the patch and plasma concentrations. Plasma-concentration over time profiles were modeled based on a one-compartment model with a time lag, a zero-order input (describing a constant absorption via skin into central circulation) and first-order elimination. Corresponding mathematical models for single- and multiple-dose administration were developed. After single-dose administration of rotigotine patches (using 2, 4 or 8 mg/day) in healthy subjects, a constant in vivo absorption was present after a minor time lag (2-3 h). On days 27 and 30 of the multiple-dose study in patients with PD, absorption was constant during patch-on periods and resembled zero-order kinetics. Deconvolution based on rotigotine pharmacokinetic profiles after single- or multiple-dose administration of the once-daily patch demonstrated that in vivo absorption of rotigotine showed constant input through the skin into the central circulation (resembling zero-order kinetics). Continuous absorption through the skin is a basis for stable drug exposure.

Comparing Sources of Storm-Time Ring Current O+

NASA Astrophysics Data System (ADS)

Kistler, L. M.

2015-12-01

The first observations of the storm-time ring current composition using AMPTE/CCE data showed that the O+ contribution to the ring current increases significantly during storms. The ring current is predominantly formed from inward transport of the near-earth plasma sheet. Thus the increase of O+ in the ring current implies that the ionospheric contribution to the plasma sheet has increased. The ionospheric plasma that reaches the plasma sheet can come from both the cusp and the nightside aurora. The cusp outflow moves through the lobe and enters the plasma sheet through reconnection at the near-earth neutral line. The nightside auroral outflow has direct access to nightside plasma sheet. Using data from Cluster and the Van Allen Probes spacecraft, we compare the development of storms in cases where there is a clear input of nightside auroral outflow, and in cases where there is a significant cusp input. We find that the cusp input, which enters the tail at ~15-20 Re becomes isotropized when it crosses the neutral sheet, and becomes part of the hot (>1 keV) plasma sheet population as it convects inward. The auroral outflow, which enters the plasma sheet closer to the earth, where the radius of curvature of the field line is larger, does not isotropize or become significantly energized, but remains a predominantly field aligned low energy population in the inner magnetosphere. It is the hot plasma sheet population that gets accelerated to high enough energies in the inner magnetosphere to contribute strongly to the ring current pressure. Thus it appears that O+ that enters the plasma sheet further down the tail has a greater impact on the storm-time ring current than ions that enter closer to the earth.

TOPICA/TORIC integration for self-consistent antenna and plasma analysis

NASA Astrophysics Data System (ADS)

Maggiora, Riccardo; Lancellotti, Vito; Milanesio, Daniele; Kyrytsya, Volodymyr; Vecchi, Giuseppe; Bonoli, Paul T.; Wright, John C.

2006-10-01

TOPICA [1] is a numerical suite conceived for prediction and analysis of plasma-facing antennas. It can handle real-life 3D antenna geometries (with housing, Faraday screen, etc.) as well as a realistic plasma model, including measured density and temperature profiles. TORIC [2] solves the finite Larmor radius wave equations in the ICRF regime in arbitrary axisymmetric toroidal plasmas. Due to the approach followed in developing TOPICA (i.e. the formal splitting of the problem in the vacuum region around the antenna and the plasma region inside the toroidal chamber), the code lends itself to handle toroidal plasmas, provided TORIC is run independently to yield the plasma surface admittance tensorsY (m,m',n). The latter enter directly into the integral equations solved by TOPICA, thus allowing a far more accurate plasma description that accounts for curvature effects. TOPICA outputs comprise, among others, the EM fields in front of the plasma: these can in turn be input to TORIC, in order to self-consistently determine the EM field propagation in the plasma. In this work, we report on the theory underlying the TOPICA/TORIC integration and the ongoing evolution of the two codes. [1] V. Lancellotti et al., Nucl. Fusion, 46 (2006) S476 [2] M. Brambilla, Plasma Phys. Contr. Fusion (1999) 41 1

A collisional-radiative model of iron vapour in a thermal arc plasma

NASA Astrophysics Data System (ADS)

Baeva, M.; Uhrlandt, D.; Murphy, A. B.

2017-06-01

A collisional-radiative model for the ground state and fifty effective excited levels of atomic iron, and one level for singly-ionized iron, is set up for technological plasmas. Attention is focused on the population of excited states of atomic iron as a result of excitation, de-excitation, ionization, recombination and spontaneous emission. Effective rate coefficients for ionization and recombination, required in non-equilibrium plasma transport models, are also obtained. The collisional-radiative model is applied to a thermal arc plasma. Input parameters for the collisional-radiative model are provided by a magnetohydrodynamic simulation of a gas-metal welding arc, in which local thermodynamic equilibrium is assumed and the treatment of the transport of metal vapour is based on combined diffusion coefficients. The results clearly identify the conditions in the arc, under which the atomic state distribution satisfies the Boltzmann distribution, with an excitation temperature equal to the plasma temperature. These conditions are met in the central part of the arc, even though a local temperature minimum occurs here. This provides assurance that diagnostic methods based on local thermodynamic equilibrium, in particular those of optical emission spectroscopy, are reliable here. In contrast, deviations from the equilibrium atomic-state distribution are obtained in the near-electrode and arc fringe regions. As a consequence, the temperatures determined from the ratio of line intensities and number densities obtained from the emission coefficient in these regions are questionable. In this situation, the collisional-radiative model can be used as a diagnostic tool to assist in the interpretation of spectroscopic measurements.

Computer simulation techniques for artificial modification of the ionosphere. Final report 31 jan 79-30 apr 81

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vance, B.; Mendillo, M.

1981-04-30

A three-dimensional model of the ionosphere was developed including chemical reactions and neutral and plasma transport. The model uses Finite Element Simulation to simulate ionospheric modification rather than solving a set of differential equations. The initial conditions of the Los Alamos Scientific Laboratory experiments, Lagopedo Uno and Dos, were input to the model, and these events were simulated. Simulation results were compared to ground and rocketborne electron-content measurements. A simulation of the transport of released SF6 was also made.

A modified Monte Carlo model for the ionospheric heating rates

NASA Technical Reports Server (NTRS)

Mayr, H. G.; Fontheim, E. G.; Robertson, S. C.

1972-01-01

A Monte Carlo method is adopted as a basis for the derivation of the photoelectron heat input into the ionospheric plasma. This approach is modified in an attempt to minimize the computation time. The heat input distributions are computed for arbitrarily small source elements that are spaced at distances apart corresponding to the photoelectron dissipation range. By means of a nonlinear interpolation procedure their individual heating rate distributions are utilized to produce synthetic ones that fill the gaps between the Monte Carlo generated distributions. By varying these gaps and the corresponding number of Monte Carlo runs the accuracy of the results is tested to verify the validity of this procedure. It is concluded that this model can reduce the computation time by more than a factor of three, thus improving the feasibility of including Monte Carlo calculations in self-consistent ionosphere models.

Charging of nanoparticles in stationary plasma in a gas aggregation cluster source

NASA Astrophysics Data System (ADS)

Blažek, J.; Kousal, J.; Biederman, H.; Kylián, O.; Hanuš, J.; Slavínská, D.

2015-10-01

Clusters that grow into nanoparticles near the magnetron target of the gas aggregation cluster source (GAS) may acquire electric charge by collecting electrons and ions or through other mechanisms like secondary- or photo-electron emissions. The region of the GAS close to magnetron may be considered as stationary plasma. The steady state charge distribution on nanoparticles can be determined by means of three possible models—fluid model, kinetic model and model employing Monte Carlo simulations—of cluster charging. In the paper the mathematical and numerical aspects of these models are analyzed in detail and close links between them are clarified. Among others it is shown that Monte Carlo simulation may be considered as a particular numerical technique of solving kinetic equations. Similarly the equations of the fluid model result, after some approximation, from averaged kinetic equations. A new algorithm solving an in principle unlimited set of kinetic equations is suggested. Its efficiency is verified on physical models based on experimental input data.

Production of nitric oxide using a microwave plasma torch and its application to fungal cell differentiation

NASA Astrophysics Data System (ADS)

Na, Young Ho; Kumar, Naresh; Kang, Min-Ho; Cho, Guang Sup; Choi, Eun Ha; Park, Gyungsoon; Uhm, Han Sup

2015-03-01

The generation of nitric oxide by a microwave plasma torch is proposed for its application to cell differentiation. A microwave plasma torch was developed based on basic kinetic theory. The analytical theory indicates that nitric oxide density is nearly proportional to oxygen molecular density and that the high-temperature flame is an effective means of generating nitric oxide. Experimental data pertaining to nitric oxide production are presented in terms of the oxygen input in units of cubic centimeters per minute. The apparent length of the torch flame increases as the oxygen input increases. The various levels of nitric oxide are observed depending on the flow rate of nitrogen gas, the mole fraction of oxygen gas, and the microwave power. In order to evaluate the potential of nitric oxide as an activator of cell differentiation, we applied nitric oxide generated from the microwave plasma torch to a model microbial cell (Neurospora crassa: non-pathogenic fungus). Germination and hyphal differentiation of fungal cells were not dramatically changed but there was a significant increase in spore formation after treatment with nitric oxide. In addition, the expression level of a sporulation related gene acon-3 was significantly elevated after 24 h upon nitric oxide treatment. Increase in the level of nitric oxide, nitrite and nitrate in water after nitric oxide treatment seems to be responsible for activation of fungal sporulation. Our results suggest that nitric oxide generated by plasma can be used as a possible activator of cell differentiation and development.

2D modeling of electromagnetic waves in cold plasmas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Crombé, K.; Van Eester, D.; Koch, R.

2014-02-12

The consequences of sheath (rectified) electric fields, resulting from the different mobility of electrons and ions as a response to radio frequency (RF) fields, are a concern for RF antenna design as it can cause damage to antenna parts, limiters and other in-vessel components. As a first step to a more complete description, the usual cold plasma dielectric description has been adopted, and the density profile was assumed to be known as input. Ultimately, the relevant equations describing the wave-particle interaction both on the fast and slow timescale will need to be tackled but prior to doing so was feltmore » as a necessity to get a feeling of the wave dynamics involved. Maxwell's equations are solved for a cold plasma in a 2D antenna box with strongly varying density profiles crossing also lower hybrid and ion-ion hybrid resonance layers. Numerical modelling quickly becomes demanding on computer power, since a fine grid spacing is required to capture the small wavelengths effects of strongly evanescent modes.« less

A magnetospheric signature of some F layer positive storms

NASA Technical Reports Server (NTRS)

Miller, N. J.; Mayr, H. G.; Grebowsky, J. M.; Harris, I.; Tulunay, Y. K.

1981-01-01

Calculations of electron density distributions in the global thermosphere-ionosphere system perturbed by high-latitude thermospheric heating are presented which indicate a link between the heating and magnetospheric plasma disturbances near the equator. The calculations were made using a self-consistent model of the global sunlit thermosphere-ionosphere system describing the evolution of equatorial plasma disturbances. The heat input is found to cause electron density enhancements that propagate along magnetic field lines from the F2 maximum over mid-latitudes to the equator in the magnetosphere and which correspond to the positive phase of an F layer storm. The positive phase is shown to be generated by the induction of equatorward winds that raise the mid-latitude F layer through momentum transfer from neutral atoms to ionospheric ions, which ions pull electrons with them. Model results are used to identify plasma signatures of equatorward winds and an intensified magnetospheric electric field in Explorer 45 and Arial 4 measurements taken during the positive phase of an F layer storm.

Closed loop adaptive control of spectrum-producing step using neural networks

DOEpatents

Fu, Chi Yung

1998-01-01

Characteristics of the plasma in a plasma-based manufacturing process step are monitored directly and in real time by observing the spectrum which it produces. An artificial neural network analyzes the plasma spectrum and generates control signals to control one or more of the process input parameters in response to any deviation of the spectrum beyond a narrow range. In an embodiment, a plasma reaction chamber forms a plasma in response to input parameters such as gas flow, pressure and power. The chamber includes a window through which the electromagnetic spectrum produced by a plasma in the chamber, just above the subject surface, may be viewed. The spectrum is conducted to an optical spectrometer which measures the intensity of the incoming optical spectrum at different wavelengths. The output of optical spectrometer is provided to an analyzer which produces a plurality of error signals, each indicating whether a respective one of the input parameters to the chamber is to be increased or decreased. The microcontroller provides signals to control respective controls, but these lines are intercepted and first added to the error signals, before being provided to the controls for the chamber. The analyzer can include a neural network and an optional spectrum preprocessor to reduce background noise, as well as a comparator which compares the parameter values predicted by the neural network with a set of desired values provided by the microcontroller.

Closed loop adaptive control of spectrum-producing step using neural networks

DOEpatents

Fu, C.Y.

1998-11-24

Characteristics of the plasma in a plasma-based manufacturing process step are monitored directly and in real time by observing the spectrum which it produces. An artificial neural network analyzes the plasma spectrum and generates control signals to control one or more of the process input parameters in response to any deviation of the spectrum beyond a narrow range. In an embodiment, a plasma reaction chamber forms a plasma in response to input parameters such as gas flow, pressure and power. The chamber includes a window through which the electromagnetic spectrum produced by a plasma in the chamber, just above the subject surface, may be viewed. The spectrum is conducted to an optical spectrometer which measures the intensity of the incoming optical spectrum at different wavelengths. The output of optical spectrometer is provided to an analyzer which produces a plurality of error signals, each indicating whether a respective one of the input parameters to the chamber is to be increased or decreased. The microcontroller provides signals to control respective controls, but these lines are intercepted and first added to the error signals, before being provided to the controls for the chamber. The analyzer can include a neural network and an optional spectrum preprocessor to reduce background noise, as well as a comparator which compares the parameter values predicted by the neural network with a set of desired values provided by the microcontroller. 7 figs.

A Selected Library of Transport Coefficients for Combustion and Plasma Physics Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cloutman, L.D.

2000-08-01

COYOTE and similar combustion programs based on the multicomponent Navier-Stokes equations require the mixture viscosity, thermal conductivity, and species transport coefficients as input. This report documents a model of these molecular transport coefficients that is simpler than the general theory, but which provides adequate accuracy for many purposes. This model leads to a computationally convenient, self-contained, and easy-to-use source of such data in a format suitable for use by such programs. We present the data for various neutral species in two forms. The first form is a simple functional fit to the transport coefficients. The second form is the usemore » of tabulated Lennard-Jones parameters in simple theoretical expressions for the gas-phase transport coefficients. The model then is extended to the case of a two-temperature plasma. Lennard-Jones parameters are given for a number of chemical species of interest in combustion research.« less

Improving Hall Thruster Plume Simulation through Refined Characterization of Near-field Plasma Properties

NASA Astrophysics Data System (ADS)

Huismann, Tyler D.

Due to the rapidly expanding role of electric propulsion (EP) devices, it is important to evaluate their integration with other spacecraft systems. Specifically, EP device plumes can play a major role in spacecraft integration, and as such, accurate characterization of plume structure bears on mission success. This dissertation addresses issues related to accurate prediction of plume structure in a particular type of EP device, a Hall thruster. This is done in two ways: first, by coupling current plume simulation models with current models that simulate a Hall thruster's internal plasma behavior; second, by improving plume simulation models and thereby increasing physical fidelity. These methods are assessed by comparing simulated results to experimental measurements. Assessment indicates the two methods improve plume modeling capabilities significantly: using far-field ion current density as a metric, these approaches used in conjunction improve agreement with measurements by a factor of 2.5, as compared to previous methods. Based on comparison to experimental measurements, recent computational work on discharge chamber modeling has been largely successful in predicting properties of internal thruster plasmas. This model can provide detailed information on plasma properties at a variety of locations. Frequently, experimental data is not available at many locations that are of interest regarding computational models. Excepting the presence of experimental data, there are limited alternatives for scientifically determining plasma properties that are necessary as inputs into plume simulations. Therefore, this dissertation focuses on coupling current models that simulate internal thruster plasma behavior with plume simulation models. Further, recent experimental work on atom-ion interactions has provided a better understanding of particle collisions within plasmas. This experimental work is used to update collision models in a current plume simulation code. Previous versions of the code assume an unknown dependence between particles' pre-collision velocities and post-collision scattering angles. This dissertation focuses on updating several of these types of collisions by assuming a curve fit based on the measurements of atom-ion interactions, such that previously unknown angular dependences are well-characterized.

Development of a long-slot microwave plasma source.

PubMed

Kuwata, Y; Kasuya, T; Miyamoto, N; Wada, M

2016-02-01

A 20 cm long 10 cm wide microwave plasma source was realized by inserting two 20 cm long 1.5 mm diameter rod antennas into the plasma. Plasma luminous distributions around the antennas were changed by magnetic field arrangement created by permanent magnets attached to the source. The distributions appeared homogeneous in one direction along the antenna when the spacing between the antenna and the source wall was 7.5 mm for the input microwave frequency of 2.45 GHz. Plasma density and temperature at a plane 20 cm downstream from the microwave shield were measured by a Langmuir probe array at 150 W microwave power input. The measured electron density and temperature varied over space from 3.0 × 10(9) cm(-3) to 5.8 × 10(9) cm(-3), and from 1.1 eV to 2.1 eV, respectively.

Short-Term Forecasting of Radiation Belt and Ring Current

NASA Technical Reports Server (NTRS)

Fok, Mei-Ching

2007-01-01

A computer program implements a mathematical model of the radiation-belt and ring-current plasmas resulting from interactions between the solar wind and the Earth s magnetic field, for the purpose of predicting fluxes of energetic electrons (10 keV to 5 MeV) and protons (10 keV to 1 MeV), which are hazardous to humans and spacecraft. Given solar-wind and interplanetary-magnetic-field data as inputs, the program solves the convection-diffusion equations of plasma distribution functions in the range of 2 to 10 Earth radii. Phenomena represented in the model include particle drifts resulting from the gradient and curvature of the magnetic field; electric fields associated with the rotation of the Earth, convection, and temporal variation of the magnetic field; and losses along particle-drift paths. The model can readily accommodate new magnetic- and electric-field submodels and new information regarding physical processes that drive the radiation-belt and ring-current plasmas. Despite the complexity of the model, the program can be run in real time on ordinary computers. At present, the program can calculate present electron and proton fluxes; after further development, it should be able to predict the fluxes 24 hours in advance

Suprachiasmatic GABAergic inputs to the paraventricular nucleus control plasma glucose concentrations in the rat via sympathetic innervation of the liver.

PubMed

Kalsbeek, Andries; La Fleur, Susanne; Van Heijningen, Caroline; Buijs, Ruud M

2004-09-01

Daily peak plasma glucose concentrations are attained shortly before awakening. Previous experiments indicated an important role for the biological clock, located in the suprachiasmatic nuclei (SCN), in the genesis of this anticipatory rise in plasma glucose concentrations by controlling hepatic glucose production. Here, we show that stimulation of NMDA receptors, or blockade of GABA receptors in the paraventricular nucleus of the hypothalamus (PVN) of conscious rats, caused a pronounced increase in plasma glucose concentrations. The local administration of TTX in brain areas afferent to the PVN revealed that an important part of the inhibitory inputs to the PVN was derived from the SCN. Using a transneuronal viral-tracing technique, we showed that the SCN is connected to the liver via both branches of the autonomic nervous system (ANS). The combination of a blockade of GABA receptors in the PVN with selective removal of either the sympathetic or parasympathetic branch of the hepatic ANS innervation showed that hyperglycemia produced by PVN stimulation was primarily attributable to an activation of the sympathetic input to the liver. We propose that the daily rise in plasma glucose concentrations is caused by an SCN-mediated withdrawal of GABAergic inputs to sympathetic preautonomic neurons in the PVN, resulting in an increased hepatic glucose production. The remarkable resemblance of the presently proposed control mechanism to that described previously for the control of daily melatonin rhythm suggests that the GABAergic control of sympathetic preautonomic neurons in the PVN is an important pathway for the SCN to control peripheral physiology.

VLF Transmitter Signal Power Loss to Quasi-Electrostatic Whistler Mode Waves in Regions Containing Plasma Density Irregularities

NASA Astrophysics Data System (ADS)

Bell, T. F.; Foust, F.; Inan, U. S.; Lehtinen, N. G.

2010-12-01

The energetic particles comprising the Earth’s radiation belts are an important component of Space Weather. The commonly accepted model of the quasi-steady radiation belts developed by Abel and Thorne [1998] proposes that VLF signals from powerful ground based transmitters determine the lifetimes of energetic radiation belt electrons (100 keV-1.5 MeV) on L shells in the range 1.3-2.8. The primary mechanism of interaction is pitch angle scattering during gyro-resonance. Recent observations [Starks et al., 2008] from multiple spacecraft suggest that the actual night time intensity of VLF transmitter signals in the radiation belts is approximately 20 dB below the level assumed in the Abel and Thorne model and approximately 10 dB below model values during the day. In this work we discuss one mechanism which might be responsible for a large portion of this intensity discrepancy. The mechanism is linear mode coupling between electromagnetic whistler mode waves and quasi-electrostatic whistler mode waves. As VLF electromagnetic whistler mode waves propagate through regions containing small scale (2-100 m) magnetic-field-aligned plasma density irregularities, they excite quasi-electrostatic whistler mode waves, and this excitation represents a power loss for the input waves. We construct plausible models of the irregularities in order to use numerical simulations to determine the characteristics of the mode coupling mechanism and the conditions under which the input VLF waves can lose significant power to the excited quasi-electrostatic whistler mode waves.

Development of a Power Electronics Unit for the Space Station Plasma Contactor

NASA Technical Reports Server (NTRS)

Hamley, John A.; Hill, Gerald M.; Patterson, Michael J.; Saggio, Joseph, Jr.; Terdan, Fred; Mansell, Justin D.

1994-01-01

A hollow cathode plasma contactor has been baselined as a charge control device for the Space Station (SS) to prevent deleterious interactions of coated structural components with the ambient plasma. NASA LeRC Work Package 4 initiated the development of a plasma contactor system comprised of a Power Electronics Unit (PEU), an Expellant Management Unit (EMU), a command and data interface, and a Plasma Contactor Unit (PCU). A breadboard PEU was designed and fabricated. The breadboard PEU contains a cathode heater and discharge power supply, which were required to operate the PCU, a control and auxiliary power converter, an EMU interface, a command and telemetry interface, and a controller. The cathode heater and discharge supplies utilized a push-pull topology with a switching frequency of 20 kHz and pulse-width-modulated (PWM) control. A pulse ignition circuit derived from that used in arcjet power processors was incorporated in the discharge supply for discharge ignition. An 8088 based microcontroller was utilized in the breadboard model to provide a flexible platform for controller development with a simple command/data interface incorporating a direct connection to SS Mulitplexer/Demultiplexer (MDM) analog and digital I/O cards. Incorporating this in the flight model would eliminate the hardware and software overhead associated with a 1553 serial interface. The PEU autonomously operated the plasma contactor based on command inputs and was successfully integrated with a prototype plasma contactor unit demonstrating reliable ignition of the discharge and steady-state operation.

Design of novel dual-port tapered waveguide plasma apparatus by numerical analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, D.; Zhou, R.; Yang, X. Q., E-mail: yyxxqq-mail@163.com

Microwave plasma apparatus is often of particular interest due to their superiority of low cost, electrode contamination free, and suitability for industrial production. However, there exist problems of unstable plasma and low electron density in conventional waveguide apparatus based on single port, due to low strength and non-uniformity of microwave field. This study proposes a novel dual-port tapered waveguide plasma apparatus based on power-combining technique, to improve the strength and uniformity of microwave field for the applications of plasma. A 3D model of microwave-induced plasma (field frequency 2.45 GHz) in argon at atmospheric pressure is presented. On the condition thatmore » the total input power is 500 W, simulations indicate that coherent power-combining will maximize the electric-field strength to 3.32 × 10{sup 5 }V/m and improve the uniformity of distributed microwave field, which raised 36.7% and 47.2%, respectively, compared to conventional waveguide apparatus of single port. To study the optimum conditions for industrial application, a 2D argon fluid model based on above structure is presented. It demonstrates that relatively uniform and high-density plasma is obtained at an argon flow rate of 200 ml/min. The contrastive result of electric-field distribution, electron density, and gas temperature is also valid and clearly proves the superiority of coherent power-combining to conventional technique in flow field.« less

Coupled interactions between tungsten surfaces and transient high-heat-flux deuterium plasmas

NASA Astrophysics Data System (ADS)

Takamura, S.; Uesugi, Y.

2015-03-01

Fundamental studies on the interactions between transient deuterium-plasma heat pulses and tungsten surfaces were carried out in terms of electrical, mechanical and thermal response in a compact plasma device AIT-PID (Aichi Institute of Technology-Plasma Irradiation Device). Firstly, electron-emission-induced surface-temperature increase is discussed in the surface-temperature range near tungsten's melting point, which is accomplished by controlling the sheath voltage and power transmission factor. Secondly, anomalous penetration of tungsten atomic efflux into the surrounding plasma was observed in addition to a normal layered population; it is discussed in terms of the effect of substantial tungsten influx into the deuterium plasma, which causes dissipation of plasma electron energy. Thirdly, a momentum input from pulsed plasma onto a tungsten target was observed visually. The force is estimated numerically by the accelerated ion flow to the target as well as the reaction of tungsten-vapour efflux. Finally, a discussion follows on the effects of the plasma heat pulses on the morphology of tungsten surface (originally a helium-induced ‘fuzzy’ nanostructure). A kind of bifurcated effect is obtained: melting and annealing. Open questions remain for all the phenomena observed, although sheath-voltage-dependent plasma-heat input may be a key parameter. Discussions on all these phenomena are provided by considering their implications to tokamak fusion devices.

DiMES PMI research at DIII-D in support of ITER and beyond

DOE PAGES

Rudakov, Dimitry L.; Abrams, Tyler; Ding, Rui; ...

2017-03-27

An overview of recent Plasma-Material Interactions (PMI) research at the DIII-D tokamak using the Divertor Material Evaluation System (DiMES) is presented. The DiMES manipulator allows for exposure of material samples in the lower divertor of DIII-D under well-diagnosed ITER-relevant plasma conditions. Plasma parameters during the exposures are characterized by an extensive diagnostic suite including a number of spectroscopic diagnostics, Langmuir probes, IR imaging, and Divertor Thomson Scattering. Post-mortem measurements of net erosion/deposition on the samples are done by Ion Beam Analysis, and results are modelled by the ERO and REDEP/WBC codes with plasma background reproduced by OEDGE/DIVIMP modelling based onmore » experimental inputs. This article highlights experiments studying sputtering erosion, re-deposition and migration of high-Z elements, mostly tungsten and molybdenum, as well as some alternative materials. Results are generally encouraging for use of high-Z PFCs in ITER and beyond, showing high redeposition and reduced net sputter erosion. Two methods of high-Z PFC surface erosion control, with (i) external electrical biasing and (ii) local gas injection, are also discussed. Furthermore, these techniques may find applications in the future devices.« less

Multiscale modeling and general theory of non-equilibrium plasma-assisted ignition and combustion

NASA Astrophysics Data System (ADS)

Yang, Suo; Nagaraja, Sharath; Sun, Wenting; Yang, Vigor

2017-11-01

A self-consistent framework for modeling and simulations of plasma-assisted ignition and combustion is established. In this framework, a ‘frozen electric field’ modeling approach is applied to take advantage of the quasi-periodic behaviors of the electrical characteristics to avoid the re-calculation of electric field for each pulse. The correlated dynamic adaptive chemistry (CO-DAC) method is employed to accelerate the calculation of large and stiff chemical mechanisms. The time-step is dynamically updated during the simulation through a three-stage multi-time scale modeling strategy, which utilizes the large separation of time scales in nanosecond pulsed plasma discharges. A general theory of plasma-assisted ignition and combustion is then proposed. Nanosecond pulsed plasma discharges for ignition and combustion can be divided into four stages. Stage I is the discharge pulse, with time scales of O (1-10 ns). In this stage, input energy is coupled into electron impact excitation and dissociation reactions to generate charged/excited species and radicals. Stage II is the afterglow during the gap between two adjacent pulses, with time scales of O (1 0 0 ns). In this stage, quenching of excited species dissociates O2 and fuel molecules, and provides fast gas heating. Stage III is the remaining gap between pulses, with time scales of O (1-100 µs). The radicals generated during Stages I and II significantly enhance exothermic reactions in this stage. The cumulative effects of multiple pulses is seen in Stage IV, with time scales of O (1-1000 ms), which include preheated gas temperatures and a large pool of radicals and fuel fragments to trigger ignition. For flames, plasma could significantly enhance the radical generation and gas heating in the pre-heat zone, thereby enhancing the flame establishment.

A Volume-Fraction Based Two-Phase Constitutive Model for Blood

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhao, Rui; Massoudi, Mehrdad; Hund, S.J.

2008-06-01

Mechanically-induced blood trauma such as hemolysis and thrombosis often occurs at microscopic channels, steps and crevices within cardiovascular devices. A predictive mathematical model based on a broad understanding of hemodynamics at micro scale is needed to mitigate these effects, and is the motivation of this research project. Platelet transport and surface deposition is important in thrombosis. Microfluidic experiments have previously revealed a significant impact of red blood cell (RBC)-plasma phase separation on platelet transport [5], whereby platelet localized concentration can be enhanced due to a non-uniform distribution of RBCs of blood flow in a capillary tube and sudden expansion. However,more » current platelet deposition models either totally ignored RBCs in the fluid by assuming a zero sample hematocrit or treated them as being evenly distributed. As a result, those models often underestimated platelet advection and deposition to certain areas [2]. The current study aims to develop a two-phase blood constitutive model that can predict phase separation in a RBC-plasma mixture at the micro scale. The model is based on a sophisticated theory known as theory of interacting continua, i.e., mixture theory. The volume fraction is treated as a field variable in this model, which allows the prediction of concentration as well as velocity profiles of both RBC and plasma phases. The results will be used as the input of successive platelet deposition models.« less

Total DNA input is a crucial determinant of the sensitivity of plasma cell-free DNA EGFR mutation detection using droplet digital PCR

PubMed Central

Zhao, Jing; Chen, Minjiang; Zhang, Li; Li, Longyun; Wang, Mengzhao

2017-01-01

We evaluated the use of droplet digital PCR (ddPCR) to detect plasma cell-free DNA (cfDNA) epidermal growth factor receptor (EGFR) mutations in advanced non-small cell lung cancer (NSCLC) patients. Compared with tumor-tissue-based detection, the sensitivity of ddPCR for detecting plasma cfDNA tyrosine kinase inhibitor (TKI)-sensitizing EGFR mutations was 61.3%, the specificity was 96.7%, and the consistency rate was 81.4% (?=0.605, 95% confidence interval: 0.501-0.706, p <0.0001). The sensitivity declined from 82.6% to 46.7% with decreasing cfDNA inputs (p=0.028). The plasma cfDNA concentration correlated with gender (males vs.females =11.69 ng/mL vs. 9.508 ng/mL; p=0.044), EGFR mutation status (tumor-tissue EGFR mutation-positive (EGFR M+) vs. EGFR mutation-negative (EGFR M-) = 9.61 ng/mL vs. 12.82 ng/mL; p =0.049) and specimen collection time (=2 years vs. >2 years=13.83 ng/mL vs. 6.575 ng/mL; p <0.001), and was greater in tumor-tissue EGFR M+ / plasma EGFR M+ patients than in tumor-tissue EGFR M+/plasma EGFR M- patients (11.61 vs. 7.73 ng/mL, respectively; p=0.003). Thus total cfDNA input crucially influences the sensitivity of plasma cfDNA EGFR mutation testing with ddPCR. Such analysis could be an effective supplemental test for advanced NSCLC patients. PMID:28052016

Confluence or independence of microwave plasma bullets in atmospheric argon plasma jet plumes

NASA Astrophysics Data System (ADS)

Li, Ping; Chen, Zhaoquan; Mu, Haibao; Xu, Guimin; Yao, Congwei; Sun, Anbang; Zhou, Yuming; Zhang, Guanjun

2018-03-01

Plasma bullet is the formation and propagation of a guided ionization wave (streamer), normally generated in atmospheric pressure plasma jet (APPJ). In most cases, only an ionization front produces in a dielectric tube. The present study shows that two or three ionization fronts can be generated in a single quartz tube by using a microwave coaxial resonator. The argon APPJ plumes with a maximum length of 170 mm can be driven by continuous microwaves or microwave pulses. When the input power is higher than 90 W, two or three ionization fronts propagate independently at first; thereafter, they confluence to form a central plasma jet plume. On the other hand, the plasma bullets move independently as the lower input power is applied. For pulsed microwave discharges, the discharge images captured by a fast camera show the ionization process in detail. Another interesting finding is that the strongest lightening plasma jet plumes always appear at the shrinking phase. Both the discharge images and electromagnetic simulations suggest that the confluence or independent propagation of plasma bullets is resonantly excited by the local enhanced electric fields, in terms of wave modes of traveling surface plasmon polaritons.

Entropy generation across Earth's collisionless bow shock.

PubMed

Parks, G K; Lee, E; McCarthy, M; Goldstein, M; Fu, S Y; Cao, J B; Canu, P; Lin, N; Wilber, M; Dandouras, I; Réme, H; Fazakerley, A

2012-02-10

Earth's bow shock is a collisionless shock wave but entropy has never been directly measured across it. The plasma experiments on Cluster and Double Star measure 3D plasma distributions upstream and downstream of the bow shock allowing calculation of Boltzmann's entropy function H and his famous H theorem, dH/dt≤0. The collisionless Boltzmann (Vlasov) equation predicts that the total entropy does not change if the distribution function across the shock becomes nonthermal, but it allows changes in the entropy density. Here, we present the first direct measurements of entropy density changes across Earth's bow shock and show that the results generally support the model of the Vlasov analysis. These observations are a starting point for a more sophisticated analysis that includes 3D computer modeling of collisionless shocks with input from observed particles, waves, and turbulences.

Predictive Rotation Profile Control for the DIII-D Tokamak

NASA Astrophysics Data System (ADS)

Wehner, W. P.; Schuster, E.; Boyer, M. D.; Walker, M. L.; Humphreys, D. A.

2017-10-01

Control-oriented modeling and model-based control of the rotation profile are employed to build a suitable control capability for aiding rotation-related physics studies at DIII-D. To obtain a control-oriented model, a simplified version of the momentum balance equation is combined with empirical representations of the momentum sources. The control approach is rooted in a Model Predictive Control (MPC) framework to regulate the rotation profile while satisfying constraints associated with the desired plasma stored energy and/or βN limit. Simple modifications allow for alternative control objectives, such as maximizing the plasma rotation while maintaining a specified input torque. Because the MPC approach can explicitly incorporate various types of constraints, this approach is well suited to a variety of control objectives, and therefore serves as a valuable tool for experimental physics studies. Closed-loop TRANSP simulations are presented to demonstrate the effectiveness of the control approach. Supported by the US DOE under DE-SC0010661 and DE-FC02-04ER54698.

Retention of Antibacterial Activity in Geranium Plasma Polymer Thin Films

PubMed Central

Al-Jumaili, Ahmed; Bazaka, Kateryna

2017-01-01

Bacterial colonisation of biomedical devices demands novel antibacterial coatings. Plasma-enabled treatment is an established technique for selective modification of physicochemical characteristics of the surface and deposition of polymer thin films. We investigated the retention of inherent antibacterial activity in geranium based plasma polymer thin films. Attachment and biofilm formation by Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli was significantly reduced on the surfaces of samples fabricated at 10 W radio frequency (RF) power, compared to that of control or films fabricated at higher input power. This was attributed to lower contact angle and retention of original chemical functionality in the polymer films fabricated under low input power conditions. The topography of all surfaces was uniform and smooth, with surface roughness of 0.18 and 0.69 nm for films fabricated at 10 W and 100 W, respectively. Hardness and elastic modules of films increased with input power. Independent of input power, films were optically transparent within the visible wavelength range, with the main absorption at ~290 nm and optical band gap of ~3.6 eV. These results suggest that geranium extract-derived polymers may potentially be used as antibacterial coatings for contact lenses. PMID:28902134

DOE Office of Scientific and Technical Information (OSTI.GOV)

Andreev, V. V., E-mail: vvandreev@mail.ru; Vasileska, I., E-mail: ivonavasileska@yahoo.com; Korneeva, M. A., E-mail: korneevama@mail.ru

A pulse-periodic 2.45-GHz electron-cyclotron resonance plasma source on the basis of a permanent- magnet mirror trap has been constructed and tested. Variations in the discharge parameters and the electron temperature of argon plasma have been investigated in the argon pressure range of 1 × 10{sup –4} to 4 × 10{sup –3} Torr at a net pulsed input microwave power of up to 600 W. The plasma electron temperature in the above ranges of gas pressures and input powers has been measured by a Langmuir probe and determined using optical emission spectroscopy (OES) from the intensity ratios of spectral lines. Themore » OES results agree qualitatively and quantitatively with the data obtained using the double probe.« less

On-site SiH4 generator using hydrogen plasma generated in slit-type narrow gap

NASA Astrophysics Data System (ADS)

Takei, Norihisa; Shinoda, Fumiya; Kakiuchi, Hiroaki; Yasutake, Kiyoshi; Ohmi, Hiromasa

2018-06-01

We have been developing an on-site silane (SiH4) generator based on use of the chemical etching reaction between solid silicon (Si) and the high-density H atoms that are generated in high-pressure H2 plasma. In this study, we have developed a slit-type plasma source for high-efficiency SiH4 generation. High-density H2 plasma was generated in a narrow slit-type discharge gap using a 2.45 GHz microwave power supply. The plasma’s optical emission intensity distribution along the slit was measured and the resulting distribution was reflected by both the electric power distribution and the hydrogen gas flow. Because the Si etching rate strongly affects the SiH4 generation rate, the Si etching behavior was investigated with respect to variations in the experimental parameters. The weight etch rate increased monotonically with increasing input microwave power. However, the weight etch rate decreased with increasing H2 pressure and an increasing plasma gap. This reduction in the etch rate appears to be related to shrinkage of the plasma generation area because increased input power is required to maintain a constant plasma area with increasing H2 pressure and the increasing plasma gap. Additionally, the weight etch rate also increases with increasing H2 flow rate. The SiH4 generation rate of the slit-type plasma source was also evaluated using gas-phase Fourier transform infrared absorption spectroscopy and the material utilization efficiencies of both Si and the H2 gas for SiH4 gas formation were discussed. The main etch product was determined to be SiH4 and the developed plasma source achieved a SiH4 generation rate of 10 sccm (standard cubic centimeters per minute) at an input power of 900 W. In addition, the Si utilization efficiency exceeded 60%.

Effect of Reactor Design on the Plasma Treatment of NOx

DTIC Science & Technology

1998-10-01

control parameter is the input energy density. Consequently, different reactor designs should yield basically the same plasma chemistry if the experiments are performed under identical gas composition and temperature conditions.

Thermodynamic and Transport Properties of Real Air Plasma in Wide Range of Temperature and Pressure

NASA Astrophysics Data System (ADS)

Wang, Chunlin; Wu, Yi; Chen, Zhexin; Yang, Fei; Feng, Ying; Rong, Mingzhe; Zhang, Hantian

2016-07-01

Air plasma has been widely applied in industrial manufacture. In this paper, both dry and humid air plasmas' thermodynamic and transport properties are calculated in temperature 300-100000 K and pressure 0.1-100 atm. To build a more precise model of real air plasma, over 70 species are considered for composition. Two different methods, the Gibbs free energy minimization method and the mass action law method, are used to determinate the composition of the air plasma in a different temperature range. For the transport coefficients, the simplified Chapman-Enskog method developed by Devoto has been applied using the most recent collision integrals. It is found that the presence of CO2 has almost no effect on the properties of air plasma. The influence of H2O can be ignored except in low pressure air plasma, in which the saturated vapor pressure is relatively high. The results will serve as credible inputs for computational simulation of air plasma. supported by the National Key Basic Research Program of China (973 Program)(No. 2015CB251002), National Natural Science Foundation of China (Nos. 51521065, 51577145), the Science and Technology Project Funds of the Grid State Corporation (SGTYHT/13-JS-177), the Fundamental Research Funds for the Central Universities, and State Grid Corporation Project (GY71-14-004)

Plasma core power exhaust in ELMy H-Mode in JET with ITER-Like Wall

NASA Astrophysics Data System (ADS)

Guillemaut, C.; Metzger, C.; Appel, L.; Drewelow, P.; Horvath, L.; Matthews, G. F.; Szepesi, G.; Solano, E. R.; contributors, JET

2018-07-01

The mitigation of target heat load in future steady state fusion devices will require dissipation of a significant amount of power through radiation. Plasma operations relying on ELMy H-modes could be problematic since ELMs may transport substantial amounts of power to the target without significant dissipation. Therefore, estimation of the average ELM power exhaust from the plasma core is crucial to evaluate the potential limitation on the power dissipation in ELMy H-mode regime. A series of more than 50 Type-I ELMy H-mode discharges in JET with ITER-Like Wall (JET-ILW) with a wide range of conditions has been used here to compare the average ELM power to the average input power. The effect of input power, ELM frequency, plasma current, confinement and radiation on ELM power exhaust has been studied and reported in this paper. Good agreement has been found here with previous studies made in carbon machines. This work suggests that it should not be possible to dissipate more than 70%–80% of the input power in Type-I ELMy H-modes in JET-ILW which is consistent with the maximum radiative fraction found experimentally.

The injection of microorganisms into an atmospheric pressure rf-driven microplasma

NASA Astrophysics Data System (ADS)

Maguire, P. D.; Mahony, C. M. O.; Diver, D.; Mariotti, D.; Bennet, E.; Potts, H.; McDowell, D. A.

2013-09-01

The introduction of living organisms, such as bacteria, into atmospheric pressure microplasmas offers a unique means to study certain physical mechanisms in individual microorganisms and also help understand the impact of macroscopic entities and liquid droplets on plasma characteristics. We present the characterization of an RF-APD operating at 13.56 MHz and containing microorganisms in liquid droplets emitted from a nebulizer, with the spray entrained in a gas flow by a gas shroud and passed into the plasma source. We report successful microorganism injection and transmission through the plasma with stable plasma operation of at least one hour. Diagnostics include RF electrical characterization, optical emission spectrometry and electrostatic deflection to investigate microorganism charging. A close-coupled Impedans Octiv VI probe indicates source efficiencies of 10 to 15%. The introduction of the droplets/microorganisms results in increased plasma conductivity and reduced capacitance, due to their impact on electron density and temperature. An electrical model will be presented based on diagnostic data and deflection studies with input from simulations of charged aerosol diffusion and evaporation. Engineering and Physical Sciences Research Council EP/K006088, EP/K006142.

Spatial distribution of CH3 and CH2 radicals in a methane rf discharge

NASA Astrophysics Data System (ADS)

Sugai, H.; Kojima, H.; Ishida, A.; Toyoda, H.

1990-06-01

Spatial distributions of neutral radicals CH3 and CH2 in a capacitively coupled rf glow discharge of methane were measured by threshold ionization mass spectrometry. A strong asymmetry of the density profile was found for the CH2 radical in the high-pressure (˜100 mTorr) discharge. In addition, comprehensive measurements of electron energy distribution, ionic composition, and radical sticking coefficient were made to use as inputs to theoretical modeling of radicals in the methane plasma. The model predictions agree substantially with the measured radical distributions.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gao, Ruilin; Yuan, Chengxun, E-mail: yuancx@hit.edu.cn, E-mail: zhouzx@hit.edu.cn; Jia, Jieshu

The interaction between microwave and large area plasma is crucially important for space communication. Gas pressure, input power, and plasma volume are critical to both the microwave electromagnetic wave phase shift and electron density. This paper presents a novel type of large coaxial gridded hollow cathode plasma having a 50 cm diameter and a 40 cm thickness. Microwave characteristics are studied using a microwave measurement system that includes two broadband antennae in the range from 2 GHz to 18 GHz. The phase shift under varying gas pressure and input power is shown. In addition, the electron density n{sub e}, whichmore » varies from 1.2 × 10{sup 16} m{sup −3} to 8.7 × 10{sup 16} m{sup −3} under different discharge conditions, is diagnosed by the microwave system. The measured results accord well with those acquired by Langmuir Probe measurement and show that the microwave properties in the large volume hollow cathode discharge significantly depend on the input power and gas pressure.« less

Resource Tracking Model Updates and Trade Studies

NASA Technical Reports Server (NTRS)

Chambliss, Joe; Stambaugh, Imelda; Moore, Michael

2016-01-01

The Resource tracking model has been updated to capture system manager and project manager inputs. Both the Trick/GUNNS RTM simulator and the RTM mass balance spreadsheet have been revised to address inputs from system managers and to refine the way mass balance is illustrated. The revisions to the RTM included addition of a Plasma Pyrolysis Assembly (PPA) to recover hydrogen from Sabatier reactor methane which was vented in the prior version of the RTM. The effect of the PPA on the overall balance of resources in an exploration vehicle is illustrated in the increased recycle of vehicle oxygen. Additionally simulation of EVAs conducted from the exploration module was added. Since the focus of the exploration module is to provide a habitat during deep space operations the EVA simulation approach to EVA is based on ISS EVA protocol and processes. Case studies have been run to show the relative effect of performance changes on vehicle resources.

Analysis of energy recovery potential using innovative technologies of waste gasification.

PubMed

Lombardi, Lidia; Carnevale, Ennio; Corti, Andrea

2012-04-01

In this paper, two alternative thermo-chemical processes for waste treatment were analysed: high temperature gasification and gasification associated to plasma process. The two processes were analysed from the thermodynamic point of view, trying to reconstruct two simplified models, using appropriate simulation tools and some support data from existing/planned plants, able to predict the energy recovery performances by process application. In order to carry out a comparative analysis, the same waste stream input was considered as input to the two models and the generated results were compared. The performances were compared with those that can be obtained from conventional combustion with energy recovery process by means of steam turbine cycle. Results are reported in terms of energy recovery performance indicators as overall energy efficiency, specific energy production per unit of mass of entering waste, primary energy source savings, specific carbon dioxide production. Copyright © 2011 Elsevier Ltd. All rights reserved.

Parametric dependence of ion temperature and relative density in the NASA Lewis SUMMA facility. [superconducting magnetic mirror

NASA Technical Reports Server (NTRS)

Snyder, A.; Lauver, M. R.; Patch, R. W.

1976-01-01

Further hot-ion plasma experiments were conducted in the SUMMA superconducting magnetic mirror facility. A steady-state ExB plasma was formed by applying a strong radially inward dc electric field between cylindrical anodes and hollow cathodes located near the magnetic mirror maxima. Extending the use of water cooling to the hollow cathodes, in addition to the anodes, resulted in higher maximum power input to the plasma. Steady-state hydrogen plasmas with ion kinetic temperatures as high as 830 eV were produced. Functional relations were obtained empirically among the plasma current, voltage, magnetic flux density, ion temperature, and relative ion density. The functional relations were deduced by use of a multiple correlation analysis. Data were obtained for midplane magnetic fields from 0.5 to 3.37 tesla and input power up to 45 kW. Also, initial absolute electron density measurements are reported from a 90 deg Thomson scattering laser system.

Effects of pulse frequency of input power on the physical and chemical properties of pulsed streamer discharge plasmas in water

NASA Astrophysics Data System (ADS)

Ruma; Lukes, P.; Aoki, N.; Spetlikova, E.; Hosseini, S. H. R.; Sakugawa, T.; Akiyama, H.

2013-03-01

A repetitive pulsed-power modulator, which employs a magnetic pulse compression circuit with a high-speed thyristor switch, was used to study the effects of the pulse repetition rate of input power on the physical and chemical properties of pulsed discharges in water. Positive high-voltage pulses of 20 kV with repetition rates of up to 1 kHz were used to generate a discharge in water using the point-to-plane electrode geometry. By varying the pulse repetition rate, two distinct modes of the discharge plasma were formed in water. The first mode was characterized by the formation of a corona-like discharge propagating through water in the form of streamer channels. The second mode was formed typically above 500 Hz, when the formation of streamer channels in water was suppressed and all plasmas occurred inside a spheroidal aggregate of very fine gas bubbles surrounding the tip of the high-voltage electrode. The production of hydrogen peroxide, degradation of organic dye Acid Orange 7 (AO7) and inactivation of bacteria Escherichia coli by the discharge in water were studied under different discharge plasma modes in dependence on the pulse repetition rate of input power. The efficiency of both chemical and biocidal processes induced by the plasma in water decreased significantly with pulse repetition rates above 500 Hz.

Quantitative characterization of arc discharge as vacuum interface

DOE PAGES

Huang, S.; Zhu, K.; Lu, Y. R.; ...

2014-12-19

An arc discharge with channel diameters of 3 mm and 6 mm and lengths between 30mm and 60mm was experimentally investigated for its potential to function as plasma window, i.e., interface vacuum regions of different pressures. In this study, electron temperature of the plasma channel measured spectroscopically varied in the range of 7000K to 15000K, increasing with discharge current while decreasing with gas flow rate. The plasma window had a slightly positive I-V characteristics over the whole range of investigated current 30A–70 A. Measurements of pressure separation capability, which were determined by input current, gas flow rate, discharge channel diameter,more » and length, were well explained by viscosity effect and “thermal-block” effect. The experimental results of global parameters including temperature, gas flow rate, and voltage had a good agreement with the simulation results calculated by an axis-symmetry Fluent-based magneto-hydrodynamic model.« less

Research on plasma-puff initiation of high Coulomb transfer switches

NASA Technical Reports Server (NTRS)

Venable, Demetrius D.; Han, Kwang S.

1993-01-01

The plasma-puff triggering mechanism based on hypocycloidal pinch geometry was investigated to determine the optimal operating conditions for an azimuthally uniform surface flashover which initiates plasma-puff under wide ranges of fill gas pressures of Ar, He and N2. Research is presented and resulting conference papers are attached. These papers include 'Characteristics of Plasma-Puff Trigger for an Inverse-Pinch Plasma Switch'; 'Ultra-High-Power Plasma Switch INPUTS for Pulse Power Systems'; 'Characteristics of Switching Plasma in an Inverse-Pinch Switch'; 'Comparative Study of INPIStron and Spark Gap'; and 'INPIStron Switched Pulsed Power for Dense Plasma Pinches.'

Thermal plasma treatment of stormwater sediments: comparison between DC non-transferred and partially transferred arc plasma.

PubMed

Li, O L; Guo, Y; Chang, J S; Saito, N

2015-01-01

The disposal of enormous amount of stormwater sediments becomes an emerging worldwide problem. Stormwater sediments are contaminated by heavy metals, phosphorus, trace organic and hydrocarbons, and cannot be disposed without treatment. Thermal plasma decontamination technology offers a high decomposition rate in a wide range of toxic organic compound and immobilization of heavy metal. In this study, we compared the treatment results between two different modes of thermal plasma: (1) a non-transferred direct current (DC) mode and (2) a partial DC-transferred mode. The reductions of total organic carbon (TOC) were, respectively, 25% and 80% for non-transferred and partially transferred plasma, respectively. Most of the toxic organic compounds were converted majorly to CxHy. In the gaseous emission, the accumulated CxHy, CO, NO and H2S were significantly higher in partially transferred mode than in non-transferred mode. The solid analysis demonstrated that the concentrations of Ca and Fe were enriched by 500% and 40%, respectively. New chemical compositions such as KAlSi3O8, Fe3O4, NaCl and CaSO4 were formed after treatment in partially DC-transferred mode. The power inputs were 1 and 10 kW, respectively, for non-transferred DC mode and a partially DC-transferred mode. With a lower energy input, non-transferred plasma treatment can be used for decontamination of sediments with low TOC and metal concentration. Meanwhile, partially transferred thermal plasma with higher energy input is suitable for treating sediments with high TOC percentage and volatile metal concentration. The organic compounds are converted into valuable gaseous products which can be recycled as an energy source.

Factor analysis for delineation of organ structures, creation of in- and output functions, and standardization of multicenter kinetic modeling

NASA Astrophysics Data System (ADS)

Schiepers, Christiaan; Hoh, Carl K.; Dahlbom, Magnus; Wu, Hsiao-Ming; Phelps, Michael E.

1999-05-01

PET imaging can quantify metabolic processes in-vivo; this requires the measurement of an input function which is invasive and labor intensive. A non-invasive, semi-automated, image based method of input function generation would be efficient, patient friendly, and allow quantitative PET to be applied routinely. A fully automated procedure would be ideal for studies across institutions. Factor analysis (FA) was applied as processing tool for definition of temporally changing structures in the field of view. FA has been proposed earlier, but the perceived mathematical difficulty has prevented widespread use. FA was utilized to delineate structures and extract blood and tissue time-activity-curves (TACs). These TACs were used as input and output functions for tracer kinetic modeling, the results of which were compared with those from an input function obtained with serial blood sampling. Dynamic image data of myocardial perfusion studies with N-13 ammonia, O-15 water, or Rb-82, cancer studies with F-18 FDG, and skeletal studies with F-18 fluoride were evaluated. Correlation coefficients of kinetic parameters obtained with factor and plasma input functions were high. Linear regression usually furnished a slope near unity. Processing time was 7 min/patient on an UltraSPARC. Conclusion: FA can non-invasively generate input functions from image data eliminating the need for blood sampling. Output (tissue) functions can be simultaneously generated. The method is simple, requires no sophisticated operator interaction and has little inter-operator variability. FA is well suited for studies across institutions and standardized evaluations.

Bolometer Results in the Long-Microwave-Heated WEGA Stellarator

NASA Astrophysics Data System (ADS)

Zhang, D.; Otte, M.; Giannone, L.

2006-01-01

A 12 channel bolometer camera based on a gold foil absorber has been installed on the WEGA stellarator to measure the radiation power losses of the plasma. The measured total radiation power is typically less than 30% of the ECRH input power. However, this radiated power fraction depends on the ECRH input power, the magnetic configuration and the field strength as well as the working gas. For separatrix-bounded configurations, core-peaked radiation intensity profiles are usually detected, while in a limiter-configuration they are flatter, broader and more asymmetric. In addition, significant radiation originating from the SOL region is measured for all the cases studied. The SOL radiation changes with changing the plasma-wave interaction region, indicating a strong correlation between radiation and power deposition. Under the WEGA-plasma conditions (Te<10 eV), it is considered that the radiation profile reflects the plasma pressure associated with the power deposition distribution of the ECRH.

Cosmic-Ray Transport in Heliospheric Magnetic Structures. II. Modeling Particle Transport through Corotating Interaction Regions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kopp, Andreas; Wiengarten, Tobias; Fichtner, Horst

The transport of cosmic rays (CRs) in the heliosphere is determined by the properties of the solar wind plasma. The heliospheric plasma environment has been probed by spacecraft for decades and provides a unique opportunity for testing transport theories. Of particular interest for the three-dimensional (3D) heliospheric CR transport are structures such as corotating interaction regions (CIRs), which, due to the enhancement of the magnetic field strength and magnetic fluctuations within and due to the associated shocks as well as stream interfaces, do influence the CR diffusion and drift. In a three-fold series of papers, we investigate these effects bymore » modeling inner-heliospheric solar wind conditions with the numerical magnetohydrodynamic (MHD) framework Cronos (Wiengarten et al., referred as Paper I), and the results serve as input to a transport code employing a stochastic differential equation approach (this paper). While, in Paper I, we presented results from 3D simulations with Cronos, the MHD output is now taken as an input to the CR transport modeling. We discuss the diffusion and drift behavior of Galactic cosmic rays using the example of different theories, and study the effects of CIRs on these transport processes. In particular, we point out the wide range of possible particle fluxes at a given point in space resulting from these different theories. The restriction of this variety by fitting the numerical results to spacecraft data will be the subject of the third paper of this series.« less

Plasma arc welding repair of space flight hardware

NASA Technical Reports Server (NTRS)

Hoffman, David S.

1993-01-01

A technique to weld repair the main combustion chamber of Space Shuttle Main Engines has been developed. The technique uses the plasma arc welding process and active cooling to seal cracks and pinholes in the hot-gas wall of the main combustion chamber liner. The liner hot-gas wall is made of NARloy-Z, a copper alloy previously thought to be unweldable using conventional arc welding processes. The process must provide extensive heat input to melt the high conductivity NARloy-Z while protecting the delicate structure of the surrounding material. The higher energy density of the plasma arc process provides the necessary heat input while active water cooling protects the surrounding structure. The welding process is precisely controlled using a computerized robotic welding system.

Substorm Electric And Magnetic Fields In The Earth's Magnetotail: Observations Compared To The WINDMI Model

NASA Astrophysics Data System (ADS)

Srinivas, P. G.; Spencer, E. A.; Vadepu, S. K.; Horton, W., Jr.

2017-12-01

We compare satellite observations of substorm electric fields and magnetic fields to the output of a low dimensional nonlinear physics model of the nightside magnetosphere called WINDMI. The electric and magnetic field satellite data are used to calculate the E X B drift, which is one of the intermediate variables of the WINDMI model. The model uses solar wind and IMF measurements from the ACE spacecraft as input into a system of 8 nonlinear ordinary differential equations. The state variables of the differential equations represent the energy stored in the geomagnetic tail, central plasma sheet, ring current and field aligned currents. The output from the model is the ground based geomagnetic westward auroral electrojet (AL) index, and the Dst index.Using ACE solar wind data, IMF data and SuperMAG identification of substorm onset times up to December 2015, we constrain the WINDMI model to trigger substorm events, and compare the model intermediate variables to THEMIS and GEOTAIL satellite data in the magnetotail. By forcing the model to be consistent with satellite electric and magnetic field observations, we are able to track the magnetotail energy dynamics, the field aligned current contributions, energy injections into the ring current, and ensure that they are within allowable limts. In addition we are able to constrain the physical parameters of the model, in particular the lobe inductance, the plasma sheet capacitance, and the resistive and conductive parameters in the plasma sheet and ionosphere.

Hydrogen and sulfur recovery from hydrogen sulfide wastes

DOEpatents

Harkness, J.B.L.; Gorski, A.J.; Daniels, E.J.

1993-05-18

A process is described for generating hydrogen and elemental sulfur from hydrogen sulfide waste in which the hydrogen sulfide is [dis]associated under plasma conditions and a portion of the hydrogen output is used in a catalytic reduction unit to convert sulfur-containing impurities to hydrogen sulfide for recycle, the process also including the addition of an ionizing gas such as argon to initiate the plasma reaction at lower energy, a preheater for the input to the reactor and an internal adjustable choke in the reactor for enhanced coupling with the microwave energy input.

Hydrogen and sulfur recovery from hydrogen sulfide wastes

DOEpatents

Harkness, John B. L.; Gorski, Anthony J.; Daniels, Edward J.

1993-01-01

A process for generating hydrogen and elemental sulfur from hydrogen sulfide waste in which the hydrogen sulfide is associated under plasma conditions and a portion of the hydrogen output is used in a catalytic reduction unit to convert sulfur-containing impurities to hydrogen sulfide for recycle, the process also including the addition of an ionizing gas such as argon to initiate the plasma reaction at lower energy, a preheater for the input to the reactor and an internal adjustable choke in the reactor for enhanced coupling with the microwave energy input.

A very sensitive ion collection device for plasma-laser characterization.

PubMed

Cavallaro, S; Torrisi, L; Cutroneo, M; Amato, A; Sarta, F; Wen, L

2012-06-01

In this paper a very sensitive ion collection device, for diagnostic of laser ablated-target plasma, is described. It allows for reducing down to few microvolts the signal threshold at digital scope input. A standard ion collector is coupled to a transimpedance amplifier, specially designed, which increases data acquisition sensitivity by a gain ≈1100 and does not introduce any significant distortion of input signal. By time integration of current intensity, an amount of charge as small as 2.7 × 10(-2) pC can be detected for photopeak events.

An alternative possibility to equatorial plasma bubble forecasting through mathematical modeling and Digisonde data

NASA Astrophysics Data System (ADS)

Sousasantos, J.; Kherani, E. A.; Sobral, J. H. A.

2017-02-01

Equatorial plasma bubbles (EPBs), or large-scale plasma depleted regions, are one of the subjects of great interest in space weather research since such phenomena have been extensively reported to cause strong degrading effects on transionospheric radio propagation at low latitudes, especially over the Brazilian region, where satellite communication interruptions by the EPBs have been, frequently, registered. One of the most difficult tasks for this field of scientific research is the forecasting of such plasma-depleted structures. This forecasting capability would be of significant help for users of positioning/navigation systems operating in the low-latitude/equatorial region all over the world. Recently, some efforts have been made trying to assess and improve the capability of predicting the EPB events. The purpose of this paper is to present an alternative approach to EPB prediction by means of the use of mathematical numerical simulation associated with ionospheric vertical drift, obtained through Digisonde data, focusing on telling beforehand whether ionospheric plasma instability processes will evolve or not into EPB structures. Modulations in the ionospheric vertical motion induced by gravity waves prior to the prereversal enhancement occurrence were used as input in the numerical model. A comparison between the numerical results and the observed EPB phenomena through CCD all-sky image data reveals a considerable coherence and supports the hypothesis of a capability of short-term forecasting.

Numerical research of a 2D axial symmetry hybrid model for the radio-frequency ion thruster

NASA Astrophysics Data System (ADS)

Chenchen, WU; Xinfeng, SUN; Zuo, GU; Yanhui, JIA

2018-04-01

Since the high efficiency discharge is critical to the radio-frequency ion thruster (RIT), a 2D axial symmetry hybrid model has been developed to study the plasma evolution of RIT. The fluid method and the drift energy correction of the electron energy distribution function (EEDF) are applied to the analysis of the RIT discharge. In the meantime, the PIC-MCC method is used to investigate the ion beam current extraction character for the plasma plume region. The beam current simulation results, with the hybrid model, agree well with the experimental results, and the error is lower than 11%, which shows the validity of the model. The further study shows there is an optimal ratio for the radio-frequency (RF) power and the beam current extraction power under the fixed RIT configuration. And the beam extraction efficiency will decrease when the discharge efficiency beyond a certain threshold (about 87 W). As the input parameters of the hybrid model are all the design values, it can be directly used to the optimum design for other kinds of RITs and radio-frequency ion sources.

MODEL-INDEPENDENT LIMITS ON THE LINE-OF-SIGHT DEPTH OF CLUSTERS OF GALAXIES USING X-RAY AND SUNYAEV-ZEL'DOVICH DATA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mahdavi, Andisheh; Chang Weihan

2011-07-01

We derive a model-independent expression for the minimum line-of-sight extent of the hot plasma in a cluster of galaxies. The only inputs are the 1-5 keV X-ray surface brightness and the Comptonization from Sunyaev-Zel'dovich (SZ) data. No a priori assumptions regarding equilibrium or geometry are required. The method applies when the X-ray emitting material has temperatures anywhere between 0.3 keV and 20 keV and metallicities between 0 and twice solar-conditions fulfilled by nearly all intracluster plasma. Using this method, joint APEX-SZ and Chandra X-ray Observatory data on the Bullet Cluster yield a lower limit of 400 {+-} 56 kpc onmore » the half-pressure depth of the main component, limiting it to being at least spherical, if not cigar-shaped primarily along the line of sight.« less

First plasma and tissue pharmacokinetic study of the YSNSG cyclopeptide, a new integrin antagonist, using microdialysis.

PubMed

Slimano, Florian; Djerada, Zoubir; Bouchene, Salim; Van Gulick, Laurence; Brassart-Pasco, Sylvie; Dukic, Sylvain

2017-07-15

The YSNSG peptide is a synthetic peptide targeting α v β 3 integrin. This peptide exhibits promising activity in vitro and in vivo against melanoma. To determine pharmacokinetic parameters and predictive active doses in the central nervous system (CNS) and subcutaneous tissue (SC), we conducted microdialysis coupled with pharmacokinetic modeling and Monte Carlo simulation. After a recovery period of surgical procedures, a microdialysis probe was inserted in the caudate and in subcutaneous tissue. Plasma samples and dialysates collected 5h after YSNSG intravenous administration (10mg/kg) were analyzed by UPLC-MS/MS. A nonlinear mixed-effect modeling approach implemented in Monolix® 2016R1 was performed. Model selection and evaluation were based on the usual diagnostic plot, precision and information criteria. The primary plasma and tissue pharmacokinetic parameters were comparable with those of other integrin antagonists, such as cilengitide or ATN-161. Tissue/plasma and brain/plasma area under the curve (AUC) ratio were 66.2±21.6% and 3.6±4.7%, respectively. Two models of 2-compartments with an additional microdialysis compartment, parameterized as rate constants (k for elimination, k12/k21 and k13/k31 for distribution) and volumes (central V1 and peripheral microdialysis compartment V3) with zero-order input were selected to describe the dialysate concentrations in CNS and SC. The inter-individual variability (IIV) was described by exponential terms, and residual variability was described by a combined additive and proportional error model. Individual AUC (plasma and tissues) values were derived for each animal using the Empirical-Bayes-Estimates of the individual parameters. The regimens needed to achieve an in vitro predetermined target concentration in tissues were studied by Monte Carlo simulations using Monolix® 2016R1. YSNSG pharmacokinetic parameters show promising results in terms of subcutaneous disposition. Further investigations into such processes as encapsulation and intratumoral disposition are currently being conducted. Copyright © 2017 Elsevier B.V. All rights reserved.

Super Configuration Accounting Equation of State for WDM and HED plasma

NASA Astrophysics Data System (ADS)

Lee, T. G.; Busquet, M.; Gilles, D.; Klapisch, M.

2017-10-01

Rad-Hydro numerical codes require Equation of State (EOS) and opacities. We describe a procedure to obtain an EOS compatible with our STA opacity model. We use our relativistic super-configuration code - STA-2.5 to compute the average 〈 Z 〉 and excitation-ionization internal energy U and chemical potential _. These and other data will serve as basic inputs into a Yukawa Monte-Carlo improved version of quotidian EOS, known as YMCQ. The screening in the Yukawa potential describing the ion-ion interaction is modified by the data from STA. This integrated procedure yields the excess internal energy due to the non-ideal behavior of the EOS concordant with our opacity model and allows us to have an EOS model applicable from solid matter to very tenuous plasmas as found in laser fusion, astrophysics, or tokamaks. We shall present its application to Carbon, Aluminum and Iron. This work is made possible by a financial support from DOE/NNSA.

Analysis of inner and outer zone: OGO-1 and OGO-2 electron spectrometer and ion chamber data

NASA Technical Reports Server (NTRS)

Pfitzer, K. A.

1972-01-01

The dynamic processes governing the acceleration and loss of electrons in the radiation zones are investigated. The radial diffusion coefficient was determined for a McIlwain parameter between 1.6 and 2.2 for electrons having a first adiabatic invariant of 12 MeV/gauss. The coefficient is larger than earlier values and suggests that there exists a lower limit to the fluxes in the inner zone. The agreement between observed and calculated magnetic fields and particle fluxes is improved by using solar wind pressure as input to the magnetic field models. Changes in the plasma pressure can cause apparent local time asymmetries in particle flux. A comparison of the magnetic field models with observed location of the trapping boundary also indicates the need for including distributed currents within the magnetosphere. The high latitude trapping boundary is only weakly dependent on A sub p, and the trapping boundary data are improved by including in the models a stand-off distance which varies with the plasma pressure.

Overview of the ArbiTER edge plasma eigenvalue code

NASA Astrophysics Data System (ADS)

Baver, Derek; Myra, James; Umansky, Maxim

2011-10-01

The Arbitrary Topology Equation Reader, or ArbiTER, is a flexible eigenvalue solver that is currently under development for plasma physics applications. The ArbiTER code builds on the equation parser framework of the existing 2DX code, extending it to include a topology parser. This will give the code the capability to model problems with complicated geometries (such as multiple X-points and scrape-off layers) or model equations with arbitrary numbers of dimensions (e.g. for kinetic analysis). In the equation parser framework, model equations are not included in the program's source code. Instead, an input file contains instructions for building a matrix from profile functions and elementary differential operators. The program then executes these instructions in a sequential manner. These instructions may also be translated into analytic form, thus giving the code transparency as well as flexibility. We will present an overview of how the ArbiTER code is to work, as well as preliminary results from early versions of this code. Work supported by the U.S. DOE.

Energy Conservation and Conversion in NIMROD Computations of Magnetic Reconnection

NASA Astrophysics Data System (ADS)

Maddox, J. A.; Sovinec, C. R.

2017-10-01

Previous work modeling magnetic relaxation during non-inductive start-up at the Pegasus spherical tokamak indicates an order of magnitude gap between measured experimental temperature and simulated temperature in NIMROD. Potential causes of the plasma temperature gap include: insufficient transport modeling, too low modeled injector power input, and numerical loss of energy, as energy is not algorithmically conserved in NIMROD simulations. Simple 2D nonlinear MHD simulations explore numerical energy conservation discrepancies in NIMROD because understanding numerical loss of energy is fundamental to addressing the physical problems of the other potential causes of energy loss. Evolution of these configurations induces magnetic reconnection, which transfers magnetic energy to heat and kinetic energy. The kinetic energy is eventually damped so, magnetic energy loss must correspond to an increase in internal energy. Results in the 2D geometries indicate that numerical energy loss during reconnection depends on the temporal resolution of the dynamics. Work support from U.S. Department of Energy through a subcontract from the Plasma Science and Innovation Center.

Measurement of ozone production scaling in a helium plasma jet with oxygen admixture

NASA Astrophysics Data System (ADS)

Sands, Brian; Ganguly, Biswa

2012-10-01

Capillary dielectric barrier plasma jet devices that generate confined streamer-like discharges along a rare gas flow can produce significant quantities of reactive oxygen species with average input powers ranging from 100 mW to >1 W. We have measured spatially-resolved ozone production in a He plasma jet with O2 admixture concentrations up to 5% using absorption spectroscopy of the O3 Hartley band system. A 20-ns risetime, 10-13 kV positive unipolar voltage pulse train was used to power the discharge, with pulse repetition rates varied from 1-20 kHz. The discharge was operated in a transient glow mode to scale the input power by adjusting the gap width between the anode and downstream cathodic plane. Peak ozone number densities in the range of 10^16 - 10^17 cm-3 were measured. At a given voltage, the density of ozone increased monotonically up to 3% O2 admixture (6 mm gap) as the peak discharge current decreased by an order of magnitude. Ozone production increased with distance from the capillary, consistent with observations by other groups. Atomic oxygen production inferred from O-atom 777 nm emission intensity did not scale with ozone as the input power was increased. The spatial distribution of ozone and scaling with input power will be presented.

Restrike Particle Beam Experiments on a Dense Plasma Focus. Opening Switch Research on a Dense Plasma Focus.

DTIC Science & Technology

1985-06-01

Research on this grant has focused on plasma focus experiments in the areas of particle beam generation and as a potential repetitive opening switch...as were scaling laws for the increase of electron energy and current with input energy. The potential of the plasma focus as an opening switch was...delay line technique. The observed frequencies were most consistent with the lower hybrid frequency. Keywords include: Dense Plasma Focus , Particle Beam Generation, Opening Switch, Load Experiments, Pulsed Power.

Charging of the Van Allen Probes: Theory and Simulations

NASA Astrophysics Data System (ADS)

Delzanno, G. L.; Meierbachtol, C.; Svyatskiy, D.; Denton, M.

2017-12-01

The electrical charging of spacecraft has been a known problem since the beginning of the space age. Its consequences can vary from moderate (single event upsets) to catastrophic (total loss of the spacecraft) depending on a variety of causes, some of which could be related to the surrounding plasma environment, including emission processes from the spacecraft surface. Because of its complexity and cost, this problem is typically studied using numerical simulations. However, inherent unknowns in both plasma parameters and spacecraft material properties can lead to inaccurate predictions of overall spacecraft charging levels. The goal of this work is to identify and study the driving causes and necessary parameters for particular spacecraft charging events on the Van Allen Probes (VAP) spacecraft. This is achieved by making use of plasma theory, numerical simulations, and on-board data. First, we present a simple theoretical spacecraft charging model, which assumes a spherical spacecraft geometry and is based upon the classical orbital-motion-limited approximation. Some input parameters to the model (such as the warm plasma distribution function) are taken directly from on-board VAP data, while other parameters are either varied parametrically to assess their impact on the spacecraft potential, or constrained through spacecraft charging data and statistical techniques. Second, a fully self-consistent numerical simulation is performed by supplying these parameters to CPIC, a particle-in-cell code specifically designed for studying plasma-material interactions. CPIC simulations remove some of the assumptions of the theoretical model and also capture the influence of the full geometry of the spacecraft. The CPIC numerical simulation results will be presented and compared with on-board VAP data. This work will set the foundation for our eventual goal of importing the full plasma environment from the LANL-developed SHIELDS framework into CPIC, in order to more accurately predict spacecraft charging.

EDGE2D-EIRENE modelling of near SOL E r: possible impact on the H-mode power threshold

NASA Astrophysics Data System (ADS)

Chankin, A. V.; Delabie, E.; Corrigan, G.; Harting, D.; Maggi, C. F.; Meyer, H.; Contributors, JET

2017-04-01

Recent EDGE2D-EIRENE simulations of JET plasmas showed a significant difference between radial electric field (E r) profiles across the separatrix in two divertor configurations, with the outer strike point on the horizontal target (HT) and vertical target (VT) (Chankin et al 2016 Nucl. Mater. Energy, doi: 10.1016/j.nme.2016.10.004). Under conditions (input power, plasma density) where the HT plasma went into the H-mode, a large positive E r spike in the near scrape-off layer (SOL) was seen in the code output, leading to a very large E × B shear across the separatrix over a narrow region of a fraction of a cm width. No such E r feature was obtained in the code solution for the VT configuration, where the H-mode power threshold was found to be twice as high as in the HT configuration. It was hypothesised that the large E × B shear across the separatrix in the HT configuration could be responsible for the turbulence suppression leading to an earlier (at lower input power) L-H transition compared to the VT configuration. In the present work these ideas are extended to cover some other experimental observations on the H-mode power threshold variation with parameters which typically are not included in the multi-machine H-mode power threshold scalings, namely: ion mass dependence (isotope H-D-T exchange), dependence on the ion ∇B drift direction, and dependence on the wall material composition (ITER-like wall versus carbon wall in JET). In all these cases EDGE2D-EIRENE modelling shows larger positive E r spikes in the near SOL under conditions where the H-mode power threshold is lower, at least in the HT configuration.

Pharmaceuticals in water, fish and osprey nestlings in Delaware River and Bay

USGS Publications Warehouse

Bean, Thomas G.; Rattner, Barnett A.; Lazarus, Rebecca S.; Day, Daniel D.; Burket, S. Rebekah; Brooks, Bryan W.; Haddad, Samuel P.; Bowerman, William W.

2018-01-01

Exposure of wildlife to Active Pharmaceutical Ingredients (APIs) is likely to occur but studies of risk are limited. One exposure pathway that has received attention is trophic transfer of APIs in a water-fish-osprey food chain. Samples of water, fish plasma and osprey plasma were collected from Delaware River and Bay, and analyzed for 21 APIs. Only 2 of 21 analytes exceeded method detection limits in osprey plasma (acetaminophen and diclofenac) with plasma levels typically 2–3 orders of magnitude below human therapeutic concentrations (HTC). We built upon a screening level model used to predict osprey exposure to APIs in Chesapeake Bay and evaluated whether exposure levels could have been predicted in Delaware Bay had we just measured concentrations in water or fish. Use of surface water and BCFs did not predict API concentrations in fish well, likely due to fish movement patterns, and partitioning and bioaccumulation uncertainties associated with these ionizable chemicals. Input of highest measured API concentration in fish plasma combined with pharmacokinetic data accurately predicted that diclofenac and acetaminophen would be the APIs most likely detected in osprey plasma. For the majority of APIs modeled, levels were not predicted to exceed 1 ng/mL or method detection limits in osprey plasma. Based on the target analytes examined, there is little evidence that APIs represent a significant risk to ospreys nesting in Delaware Bay. If an API is present in fish orders of magnitude below HTC, sampling of fish-eating birds is unlikely to be necessary. However, several human pharmaceuticals accumulated in fish plasma within a recommended safety factor for HTC. It is now important to expand the scope of diet-based API exposure modeling to include alternative exposure pathways (e.g., uptake from landfills, dumps and wastewater treatment plants) and geographic locations (developing countries) where API contamination of the environment may represent greater risk.

Solar Prominence Modelling and Plasma Diagnostics at ALMA Wavelengths

NASA Astrophysics Data System (ADS)

Rodger, Andrew; Labrosse, Nicolas

2017-09-01

Our aim is to test potential solar prominence plasma diagnostics as obtained with the new solar capability of the Atacama Large Millimeter/submillimeter Array (ALMA). We investigate the thermal and plasma diagnostic potential of ALMA for solar prominences through the computation of brightness temperatures at ALMA wavelengths. The brightness temperature, for a chosen line of sight, is calculated using the densities of electrons, hydrogen, and helium obtained from a radiative transfer code under non-local thermodynamic equilibrium (non-LTE) conditions, as well as the input internal parameters of the prominence model in consideration. Two distinct sets of prominence models were used: isothermal-isobaric fine-structure threads, and large-scale structures with radially increasing temperature distributions representing the prominence-to-corona transition region. We compute brightness temperatures over the range of wavelengths in which ALMA is capable of observing (0.32 - 9.6 mm), however, we particularly focus on the bands available to solar observers in ALMA cycles 4 and 5, namely 2.6 - 3.6 mm (Band 3) and 1.1 - 1.4 mm (Band 6). We show how the computed brightness temperatures and optical thicknesses in our models vary with the plasma parameters (temperature and pressure) and the wavelength of observation. We then study how ALMA observables such as the ratio of brightness temperatures at two frequencies can be used to estimate the optical thickness and the emission measure for isothermal and non-isothermal prominences. From this study we conclude that for both sets of models, ALMA presents a strong thermal diagnostic capability, provided that the interpretation of observations is supported by the use of non-LTE simulation results.

Hollow cathode heater development for the Space Station plasma contactor

NASA Technical Reports Server (NTRS)

Soulas, George C.

1993-01-01

A hollow cathode-based plasma contactor has been selected for use on the Space Station. During the operation of the plasma contactor, the hollow cathode heater will endure approximately 12000 thermal cycles. Since a hollow cathode heater failure would result in a plasma contactor failure, a hollow cathode heater development program was established to produce a reliable heater design. The development program includes the heater design, process documents for both heater fabrication and assembly, and heater testing. The heater design was a modification of a sheathed ion thruster cathode heater. Three heaters have been tested to date using direct current power supplies. Performance testing was conducted to determine input current and power requirements for achieving activation and ignition temperatures, single unit operational repeatability, and unit-to-unit operational repeatability. Comparisons of performance testing data at the ignition input current level for the three heaters show the unit-to-unit repeatability of input power and tube temperature near the cathode tip to be within 3.5 W and 44 degrees C, respectively. Cyclic testing was then conducted to evaluate reliability under thermal cycling. The first heater, although damaged during assembly, completed 5985 ignition cycles before failing. Two additional heaters were subsequently fabricated and have completed 3178 cycles to date in an on-going test.

Enhanced energy coupling and x-ray emission in Z-pinch plasma implosions

NASA Astrophysics Data System (ADS)

Whitney, K. G.; Thornhill, J. W.; Apruzese, J. P.; Davis, J.; Deeney, C.; Coverdale, C. A.

2004-08-01

Recent experiments conducted on the Saturn pulsed-power generator at Sandia National Laboratories [R. B. Spielman et al., in Proceedings of the Second International Conference on Dense Z Pinches, Laguna Beach, CA, 1989, edited by N. R. Pereira, J. Davis, and N. Rostoker (American Institute of Physics, New York, 1989), p. 3] have produced large amounts of x-ray output, which cannot be accounted for in conventional magnetohydrodynamic (MHD) calculations. In these experiments, the Saturn current had a rise time of ~180 ns in contrast to a rise time of ~60 ns in Saturn's earlier mode of operation. In both aluminum and tungsten wire-array Z-pinch implosions, 2-4 times more x-ray output was generated than could be supplied according to one-dimensional (1D) magnetohydrodynamic calculations by the combined action of the j×B acceleration forces and ohmic heating (as described by a classical Braginskii resistivity). In this paper, we reexamine the problem of coupling transmission line circuits to plasma fluid equations and derive expressions for the Z-pinch load circuit resistance and inductance that relate these quantities in a 1D analysis to the surface resistivity of the fluid, and to the magnetic field energy that is stored in the vacuum diode, respectively. Enhanced energy coupling in this analysis, therefore, comes from enhancements to the surface resistivity, and we show that plasma resistivities approximately three orders of magnitude larger than classical are needed in order to achieve energy inputs that are comparable to the Saturn experiment x-ray outputs. Large enhancements of the plasma resistivity increase the rate of magnetic field and current diffusion, significantly modify the qualitative features of the MHD, and raise important questions as to how the plasma fluid dynamics converts enhanced energy inputs into enhanced x-ray outputs. One-dimensional MHD calculations in which resistivity values are adjusted phenomenologically are used to illustrate how various dynamical assumptions influence the way enhanced energy inputs are channeled by the fluid dynamics. Variations in the parameters of the phenomenological model are made in order to determine how sensitively they influence the dynamics and the degree to which the calculated x-ray outputs can be made to replicate the kinds of large variations in the experimental x-ray power data that were observed in three nominally identical aluminum wire shots on Saturn.

Model-independent plot of dynamic PET data facilitates data interpretation and model selection.

PubMed

Munk, Ole Lajord

2012-02-21

When testing new PET radiotracers or new applications of existing tracers, the blood-tissue exchange and the metabolism need to be examined. However, conventional plots of measured time-activity curves from dynamic PET do not reveal the inherent kinetic information. A novel model-independent volume-influx plot (vi-plot) was developed and validated. The new vi-plot shows the time course of the instantaneous distribution volume and the instantaneous influx rate. The vi-plot visualises physiological information that facilitates model selection and it reveals when a quasi-steady state is reached, which is a prerequisite for the use of the graphical analyses by Logan and Gjedde-Patlak. Both axes of the vi-plot have direct physiological interpretation, and the plot shows kinetic parameter in close agreement with estimates obtained by non-linear kinetic modelling. The vi-plot is equally useful for analyses of PET data based on a plasma input function or a reference region input function. The vi-plot is a model-independent and informative plot for data exploration that facilitates the selection of an appropriate method for data analysis. Copyright © 2011 Elsevier Ltd. All rights reserved.

The day-to-day occurrence of equatorial plasma bubbles measured from Vanimo, Papua New Guinea

NASA Astrophysics Data System (ADS)

Carter, B. A.; Yizengaw, E.; Francis, M.; Terkildsen, M. B.; Marshall, R. A.; Norman, R.; Zhang, K.

2013-12-01

An analysis of the occurrence of Equatorial Plasma Bubbles (EPBs) detected using a ground-based Global Positioning System (GPS) receiver located at Vanimo in South-east Asia will be presented. The 3-year (2000-2002) dataset employed shows that the EPB occurrence maximizes (minimizes) during the equinoxes (solstices), in good agreement with previous findings. The low-latitude ionosonde station at Vanimo is used in conjunction with the GPS receiver in an analysis of the day-to-day EPB occurrence variability during the equinox period. A superposed epoch analysis of the ionosonde data reveals that the height, and the change in height, of the F layer is 1 standard deviation (1σ) larger on the days for which EPBs were detected, compared to non-EPB days. These results are interpreted using the generalized Rayleigh-Taylor (R-T) plasma instability growth rate, for which stronger upward drift of the lower-altitude F-layer plasma promotes faster growth of EPBs after sunset. These results are then compared to the results of the Thermosphere Ionosphere Electrodynamic General Circulation Model (TIEGCM), which surprisingly show strong similarities to the observations, despite only using geomagnetic and solar activity inputs. The TIEGCM is also used to directly calculate the hourly flux-tube integrated R-T growth rate. A superposed epoch analysis reveals that the modeled R-T growth rate is a little less than 1σ higher on average for EPB days compared to non-EPB days. The implication of this result is that the TIEGCM generates almost enough day-to-day variability in order to account for the day-to-day EPB occurrence observed during the equinox. This result isn't necessarily expected due to the model's limited altitude coverage of 100-700 km (depending on solar activity) and the lack of ionospheric observation inputs. It is thought that the remaining variability could originate from either lower altitudes (e.g. atmospheric gravity waves from the troposphere) or from higher altitudes (resulting from coupling with the magnetosphere and solar wind), or potentially both. It is concluded that the continuing advancement of numerical modeling of the thermosphere and ionosphere, coupled with altitudes above and below, is required to better understand the day-to-day EPB occurrence.

The Formation of Ethane from Carbon Dioxide under Cold Plasma

NASA Astrophysics Data System (ADS)

Zhang, Xiu-ling; Zhang, Lin; Dai, Bin; Gong, Wei-min; Liu, Chang-hou

2001-04-01

Pulsed-corona plasma has been used as a new method for ethane dehydrogenation at low temperature and normal pressure using carbon dioxide as an oxidant in this paper. The effect of carbon dioxide content in the feed, power input, and flow rate of the reactants on the ethane dehydrogenation has been investigated. The experimental results show that the conversion of ethane increases with the increase in the amount of carbon dioxide in the feed. The yield of ethylene and acetylene decreases with the increase in the yield of carbon monoxide, indicating that the increased carbon dioxide leads to the part of ethylene and acetylene being oxidized to carbon monoxide. Power input is primarily an electrical parameter in pulsed-corona plasma, which plays an important role in reactant conversion and product formation. When the power input reaches 16 W, ethane conversion is 41.0% and carbon dioxide conversion is 26.3%. The total yield of ethylene and acetylene is 15.6%. The reduced flow rate of feed improves the conversion of ethane, carbon dioxide and the yield of acetylene, and induces carbon deposit as well.

Development of a miniature microwave electron cyclotron resonance plasma ion thruster for exospheric micro-propulsion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dey, Indranuj, E-mail: indranuj@aees.kyushu-u.ac.jp; Toyoda, Yuji; Yamamoto, Naoji

A miniature microwave electron cyclotron resonance plasma source [(discharge diameter)/(microwave cutoff diameter) < 0.3] has been developed at Kyushu University to be used as an ion thruster in micro-propulsion applications in the exosphere. The discharge source uses both radial and axial magnetostatic field confinement to facilitate electron cyclotron resonance and increase the electron dwell time in the volume, thereby enhancing plasma production efficiency. Performance of the ion thruster is studied at 3 microwave frequencies (1.2 GHz, 1.6 GHz, and 2.45 GHz), for low input powers (<15 W) and small xenon mass flow rates (<40 μg/s), by experimentally measuring the extractedmore » ion beam current through a potential difference of ≅1200 V. The discharge geometry is found to operate most efficiently at an input microwave frequency of 1.6 GHz. At this frequency, for an input power of 8 W, and propellant (xenon) mass flow rate of 21 μg/s, 13.7 mA of ion beam current is obtained, equivalent to an calculated thrust of 0.74 mN.« less

Locked-mode avoidance and recovery without momentum input

NASA Astrophysics Data System (ADS)

Delgado-Aparicio, L.; Rice, J. E.; Wolfe, S.; Cziegler, I.; Gao, C.; Granetz, R.; Wukitch, S.; Terry, J.; Greenwald, M.; Sugiyama, L.; Hubbard, A.; Hugges, J.; Marmar, E.; Phillips, P.; Rowan, W.

2015-11-01

Error-field-induced locked-modes (LMs) have been studied in Alcator C-Mod at ITER-Bϕ, without NBI fueling and momentum input. Delay of the mode-onset and locked-mode recovery has been successfully obtained without external momentum input using Ion Cyclotron Resonance Heating (ICRH). The use of external heating in-sync with the error-field ramp-up resulted in a successful delay of the mode-onset when PICRH > 1 MW, which demonstrates the existence of a power threshold to ``unlock'' the mode; in the presence of an error field the L-mode discharge can transition into H-mode only when PICRH > 2 MW and at high densities, avoiding also the density pump-out. The effects of ion heating observed on unlocking the core plasma may be due to ICRH induced flows in the plasma boundary, or modifications of plasma profiles that changed the underlying turbulence. This work was performed under US DoE contracts including DE-FC02-99ER54512 and others at MIT, DE-FG03-96ER-54373 at University of Texas at Austin, and DE-AC02-09CH11466 at PPPL.

Method and device for reducing overpenetration at the start of plasma arc welds

DOEpatents

Sanders, John M.; Lehmann, John M.; Ryan, Patrick M.

1998-01-01

A shim for improving plasma arc weld quality has ends tapered at about 25.degree. and notches at each end roughly centered over the corner between the tapered ends and main body of the shim. The improved shim allows lower starting plasma arc heat input and reduces the occurrence of sagging, or overpenetration, of the weld.

Kinetic models for space plasmas: Recent progress for the solar wind and the Earth's magnetosphere

NASA Astrophysics Data System (ADS)

Pierrard, V.; Moschou, S. P.; Lazar, M.; Borremans, K.; Rosson, G. Lopez

2016-11-01

Recent models for the solar wind and the inner magnetosphere have been developed using the kinetic approach. The solution of the evolution equation is used to determine the velocity distribution function of the particles and their moments. The solutions depend on the approximations and assumptions made in the development of the models. Effects of suprathermal particles often observed in space plasmas are taken into account to show their influence on the characteristics of the plasma, with specific applications for coronal heating and solar wind acceleration. We describe in particular the results obtained with the collisionless exospheric approximation based on the Lorentzian velocity distribution function for the electrons and its recent progress in three dimensions. The effects of Coulomb collisions obtained by using a Fokker-Planck term in the evolution equation were also investigated, as well as effects of the whistler wave turbulence at electron scale and the kinetic Alfven waves at the proton scale. For solar wind especially, modelling efforts with both magnetohydrodynamic and kinetic treatments have been compared and combined in order to improve the predictions in the vicinity of the Earth. Photospheric magnetograms serve as observational input in semi-empirical coronal models used for estimating the plasma characteristics up to coronal heliocentric distances taken as boundary conditions in solar wind models. The solar wind fluctuations may influence the dynamics of the space environment of the Earth and generate geomagnetic storms. In the magnetosphere of the Earth, the trajectories of the particles are simulated to study the plasmasphere, the extension of the ionosphere along closed magnetic field lines and to better understand the physical mechanisms involved in the radiation belts dynamics.

Transmission characteristics of microwave in a glow-discharge dusty plasma

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jia, Jieshu; Yuan, Chengxun, E-mail: yuancx@hit.edu.cn; Gao, Ruilin

2016-07-15

In this study, the propagation characteristics of electromagnetic wave in a glow discharge plasma with dust particles are experimentally investigated. A helium alternating current glow discharge plasmas have been successfully generated. Measurements of the plasma parameters using Langmuir probes, in the absence of dust particles, provide plasma densities (n{sub e}) of 10{sup 17 }m{sup −3} and electron temperatures (T{sub e}) ranging from 2 to 4 eV. Dusty plasmas are made by adding 30 nm radius aluminum oxide (Al{sub 2}O{sub 3}) particles into the helium plasma. The density of the dust particle (n{sub d}) in the device is about 10{sup 11}–10{sup 12 }m{sup −3}. Themore » propagation characteristics of electromagnetic waves are determined by a vector network analyzer with 4–6 GHz antennas. An apparent attenuation by the dust is observed, and the measured attenuation data are approximately in accordance with the theoretical calculations. The effects of gas pressure and input power on the propagation are also investigated. Results show that the transmission attenuation increases with the gas pressure and input power, the charged dust particles play a significant role in the microwave attenuation.« less

Loss of serum IGF-I input to the brain as an early biomarker of disease onset in Alzheimer mice

PubMed Central

Trueba-Sáiz, A; Cavada, C; Fernandez, A M; Leon, T; González, D A; Fortea Ormaechea, J; Lleó, A; Del Ser, T; Nuñez, A; Torres-Aleman, I

2013-01-01

Circulating insulin-like growth factor I (IGF-I) enters the brain and promotes clearance of amyloid peptides known to accumulate in Alzheimer's disease (AD) brains. Both patients and mouse models of AD show decreased level of circulating IGF-I enter the brain as evidenced by a lower ratio of cerebrospinal fluid/plasma IGF-I. Importantly, in presymptomatic AD mice this reduction is already manifested as a decreased brain input of serum IGF-I in response to environmental enrichment. To explore a potential diagnostic use of this early loss of IGF-I input, we monitored electrocorticogram (ECG) responses to systemic IGF-I in mice. Whereas control mice showed enhanced ECG activity after IGF-I, presymptomatic AD mice showed blunted ECG responses. Because nonhuman primates showed identically enhanced electroencephalogram (EEG) activity in response to systemic IGF-I, loss of the EEG signature of serum IGF-I may be exploited as a disease biomarker in AD patients. PMID:24301648

Matching Condition of Direct THz-Signal Detection from On-Chip Resonating Antennas with CMOS Transistors in Non-resonant Plasma Wave Mode

NASA Astrophysics Data System (ADS)

Chai, S.; Lim, S.; Kim, C.-Y.; Hong, S.

2018-06-01

This paper presents matching condition for detector at THz frequencies, which directly read signals from an integrated antenna. We use direct THz-signal detections with CMOS transistors in non-resonant plasma wave mode, which are embedded in on-chip resonating antennas. The detector detects THz envelope signals directly from the side edges of the on-chip patch antennas. The signal detection mechanism is studied in the view of the impedance conditions of the antenna and the detector. The detectors are implemented with stacked transistors structures to achieve high responsivity. The measured responsivities of the detectors with antenna impedances that were simulated to be 599.7, 912.3, 1565, and 3190.6 Ω agree well with the calculated values. Moreover, the responsivity dependence on the detector impedance is shown with two different input impedances of the detectors. Since CMOS circuit models from foundry are not accurate at frequencies higher than f t , the matching guideline between the antenna and the detector is very useful in designing high responsivity detectors. This study found that a detector has to have a large input impedance conjugately matched to the antenna's impedance to have high responsivity.

Matching Condition of Direct THz-Signal Detection from On-Chip Resonating Antennas with CMOS Transistors in Non-resonant Plasma Wave Mode

NASA Astrophysics Data System (ADS)

Chai, S.; Lim, S.; Kim, C.-Y.; Hong, S.

2018-04-01

This paper presents matching condition for detector at THz frequencies, which directly read signals from an integrated antenna. We use direct THz-signal detections with CMOS transistors in non-resonant plasma wave mode, which are embedded in on-chip resonating antennas. The detector detects THz envelope signals directly from the side edges of the on-chip patch antennas. The signal detection mechanism is studied in the view of the impedance conditions of the antenna and the detector. The detectors are implemented with stacked transistors structures to achieve high responsivity. The measured responsivities of the detectors with antenna impedances that were simulated to be 599.7, 912.3, 1565, and 3190.6 Ω agree well with the calculated values. Moreover, the responsivity dependence on the detector impedance is shown with two different input impedances of the detectors. Since CMOS circuit models from foundry are not accurate at frequencies higher than f t , the matching guideline between the antenna and the detector is very useful in designing high responsivity detectors. This study found that a detector has to have a large input impedance conjugately matched to the antenna's impedance to have high responsivity.

Initial results from a dynamic coupled magnetosphere-ionosphere-ring current model

NASA Astrophysics Data System (ADS)

Pembroke, Asher; Toffoletto, Frank; Sazykin, Stanislav; Wiltberger, Michael; Lyon, John; Merkin, Viacheslav; Schmitt, Peter

2012-02-01

In this paper we describe a coupled model of Earth's magnetosphere that consists of the Lyon-Fedder-Mobarry (LFM) global magnetohydrodynamics (MHD) simulation, the MIX ionosphere solver and the Rice Convection Model (RCM) and report some results using idealized inputs and model parameters. The algorithmic and physical components of the model are described, including the transfer of magnetic field information and plasma boundary conditions to the RCM and the return of ring current plasma properties to the LFM. Crucial aspects of the coupling include the restriction of RCM to regions where field-line averaged plasma-β ≤ 1, the use of a plasmasphere model, and the MIX ionosphere model. Compared to stand-alone MHD, the coupled model produces a substantial increase in ring current pressure and reduction of the magnetic field near the Earth. In the ionosphere, stronger region-1 and region-2 Birkeland currents are seen in the coupled model but with no significant change in the cross polar cap potential drop, while the region-2 currents shielded the low-latitude convection potential. In addition, oscillations in the magnetic field are produced at geosynchronous orbit with the coupled code. The diagnostics of entropy and mass content indicate that these oscillations are associated with low-entropy flow channels moving in from the tail and may be related to bursty bulk flows and bubbles seen in observations. As with most complex numerical models, there is the ongoing challenge of untangling numerical artifacts and physics, and we find that while there is still much room for improvement, the results presented here are encouraging.

3D numerical simulations of negative hydrogen ion extraction using realistic plasma parameters, geometry of the extraction aperture and full 3D magnetic field map

NASA Astrophysics Data System (ADS)

Mochalskyy, S.; Wünderlich, D.; Ruf, B.; Franzen, P.; Fantz, U.; Minea, T.

2014-02-01

Decreasing the co-extracted electron current while simultaneously keeping negative ion (NI) current sufficiently high is a crucial issue on the development plasma source system for ITER Neutral Beam Injector. To support finding the best extraction conditions the 3D Particle-in-Cell Monte Carlo Collision electrostatic code ONIX (Orsay Negative Ion eXtraction) has been developed. Close collaboration with experiments and other numerical models allows performing realistic simulations with relevant input parameters: plasma properties, geometry of the extraction aperture, full 3D magnetic field map, etc. For the first time ONIX has been benchmarked with commercial positive ions tracing code KOBRA3D. A very good agreement in terms of the meniscus position and depth has been found. Simulation of NI extraction with different e/NI ratio in bulk plasma shows high relevance of the direct negative ion extraction from the surface produced NI in order to obtain extracted NI current as in the experimental results from BATMAN testbed.

Atomic and molecular hydrogen gas temperatures in a low-pressure helicon plasma

NASA Astrophysics Data System (ADS)

Samuell, Cameron M.; Corr, Cormac S.

2015-08-01

Neutral gas temperatures in hydrogen plasmas are important for experimental and modelling efforts in fusion technology, plasma processing, and surface modification applications. To provide values relevant to these application areas, neutral gas temperatures were measured in a low pressure (< 10 mTorr) radiofrequency helicon discharge using spectroscopic techniques. The atomic and molecular species were not found to be in thermal equilibrium with the atomic temperature being mostly larger then the molecular temperature. In low power operation (< 1 kW), the molecular hydrogen temperature was observed to be linearly proportional to the pressure while the atomic hydrogen temperature was inversely proportional. Both temperatures were observed to rise linearly with input power. For high power operation (5-20 kW), the molecular temperature was found to rise with both power and pressure up to a maximum of approximately 1200 K. Spatially resolved measurements near a graphite target demonstrated localised cooling near the sample surface. The temporal evolution of the molecular gas temperature during a high power 1.1 ms plasma pulse was also investigated and found to vary considerably as a function of pressure.

Non-invasive probe diagnostic method for electron temperature and ion current density in atmospheric pressure plasma jet source

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, Young-Cheol; Kim, Yu-Sin; Lee, Hyo-Chang

2015-08-15

The electrical probe diagnostics are very hard to be applied to atmospheric plasmas due to severe perturbation by the electrical probes. To overcome this, the probe for measuring electron temperature and ion current density is indirectly contacted with an atmospheric jet source. The plasma parameters are obtained by using floating harmonic analysis. The probe is mounted on the quartz tube that surrounds plasma. When a sinusoidal voltage is applied to a probe contacting on a quartz tube, the electrons near the sheath at dielectric tube are collected and the probe current has harmonic components due to probe sheath nonlinearity. Frommore » the relation of the harmonic currents and amplitude of the sheath voltage, the electron temperature near the wall can be obtained with collisional sheath model. The electron temperatures and ion current densities measured at the discharge region are in the ranges of 2.7–3.4 eV and 1.7–5.2 mA/cm{sup 2} at various flow rates and input powers.« less

Microwave Assisted Helicon Plasmas

NASA Astrophysics Data System (ADS)

McKee, John; Caron, David; Jemiolo, Andrew; Scime, Earl

2017-10-01

The use of two (or more) rf sources at different frequencies is a common technique in the plasma processing industry to control ion energy characteristics separately from plasma generation. A similar approach is presented here with the focus on modifying the electron population in argon and helium plasmas. The plasma is generated by a helicon source at a frequency f0 = 13.56 MHz. Microwaves of frequency f1 = 2.45 GHz are then injected into the helicon source chamber perpendicular to the background magnetic field. The microwaves damp on the electrons via X-mode Electron Cyclotron Heating (ECH) at the upper hybrid resonance, providing additional energy input into the electrons. The effects of this secondary-source heating on electron density, temperature, and energy distribution function are examined and compared to helicon-only single source plasmas as well as numeric models suggesting that the heating is not evenly distributed. Optical Emission Spectroscopy (OES) is used to examine the impact of the energetic tail of the electron distribution on ion and neutral species via collisional excitation. Large enhancements of neutral spectral lines are observed in both Ar and He. While small enhancement of ion lines is seen in Ar, ion lines not normally present in He are observed during microwave injection. U.S. National Science Foundation Grant No. PHY-1360278.

Assessment of penetrating thermal tissue damage/spread associated with PhotonBlade™, Valleylab™ Pencil, Valleylab™ EDGE™ Coated Pencil, PlasmaBlade® 3.0S and PlasmaBlade® 4.0 for intraoperative tissue dissection using the fresh extirpated porcine muscle model

NASA Astrophysics Data System (ADS)

Bennett, Haydon E.; Taylor, Scott D.; Fugett, James H.; Shrout, Joshua L.; Davison, Paul O.; Ryan, S. Eric; Coad, James E.

2017-02-01

Penetrating thermal tissue damage/spread is an important aspect of many electrosurgical devices and correlates with effective tissue cutting, hemostasis, preservation of adjacent critical structures and tissue healing. This study compared the thermal damage/spread associated with the PhotonBlade, Valleylab Pencil, Valleylab EDGE Coated Pencil, PlasmaBlade 3.0S and PlasmaBlade 4.0, when performing a single pass dynamic tissue cut in fresh extirpated porcine longissimus muscle. These devices were used in a fashion that emulated their use in the clinical setting. Each device's thermal damage/spread, at Minimum, Median and Maximum power input settings, was assessed with nitroblue tetrazolium viability staining in the WVU Pathology Laboratory for Translational Medicine. The thermal damage/spread associated with the PhotonBlade was compared with the other devices tested based on the individual treatment results (n=179 cuts combined). In summary, the PhotonBlade overall demonstrated the least penetrating thermal tissue damage/spread, followed by the PlasmaBlade 4.0, then Valleylab Pencil and PlasmaBlade 3.0S and then Valleylab EDGE Coated Pencil in order of increasing thermal damage/spread depths.

Studies of RF sheaths and diagnostics on IShTAR

NASA Astrophysics Data System (ADS)

Crombé, K.; Devaux, S.; D'Inca, R.; Faudot, E.; Faugel, H.; Fünfgelder, H.; Heuraux, S.; Jacquot, J.; Louche, F.; Moritz, J.; Ochoukov, R.; Tripsky, M.; Van Eester, D.; Wauters, T.; Noterdaeme, J.-M.

2015-12-01

IShTAR (Ion cyclotron Sheath Test ARrangement) is a linear magnetised plasma test facility for RF sheaths studies at the Max-Planck-Institut für Plasmaphysik in Garching. In contrast to a tokamak, a test stand provides more liberty to impose the parameters and gives better access for the instrumentation and antennas. The project will support the development of diagnostic methods for characterising RF sheaths and validate and improve theoretical predictions. The cylindrical vacuum vessel has a diameter of 1 m and is 1.1 m long. The plasma is created by an external cylindrical plasma source equipped with a helical antenna that has been designed to excite the m=1 helicon mode. In inductive mode, plasma densities and electron temperatures have been characterised with a planar Langmuir probe as a function of gas pressure and input RF power. A 2D array of RF compensated Langmuir probes and a spectrometer are planned. A single strap RF antenna has been designed; the plasma-facing surface is aligned to the cylindrical plasma to ease the modelling. The probes will allow direct measurements of plasma density profiles in front of the RF antenna, and thus a detailed study of the density modifications induced by RF sheaths, which influences the coupling. The RF antenna frequency has been chosen to study different plasma wave interactions: the accessible plasma density range includes an evanescent and propagative behaviour of slow or fast waves, and allows the study of the effect of the lower hybrid resonance layer.

HOW GAS-DYNAMIC FLARE MODELS POWERED BY PETSCHEK RECONNECTION DIFFER FROM THOSE WITH AD HOC ENERGY SOURCES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Longcope, D. W.; Klimchuk, J. A.

Aspects of solar flare dynamics, such as chromospheric evaporation and flare light curves, have long been studied using one-dimensional models of plasma dynamics inside a static flare loop, subjected to some energy input. While extremely successful at explaining the observed characteristics of flares, all such models so far have specified energy input ad hoc, rather than deriving it self-consistently. There is broad consensus that flares are powered by magnetic energy released through reconnection. Recent work has generalized Petschek’s basic reconnection scenario, topological change followed by field line retraction and shock heating, to permit its inclusion in a one-dimensional flare loop model. Heremore » we compare the gas dynamics driven by retraction and shocking to those from more conventional static loop models energized by ad hoc source terms. We find significant differences during the first minute, when retraction leads to larger kinetic energies and produces higher densities at the loop top, while ad hoc heating tends to rarify the loop top. The loop-top density concentration is related to the slow magnetosonic shock, characteristic of Petschek’s model, but persists beyond the retraction phase occurring in the outflow jet. This offers an explanation for observed loop-top sources of X-ray and EUV emission, with advantages over that provided by ad hoc heating scenarios. The cooling phases of the two models are, however, notably similar to one another, suggesting that observations at that stage will yield little information on the nature of energy input.« less

A case study on the in silico absorption simulations of levothyroxine sodium immediate-release tablets.

PubMed

Kocic, Ivana; Homsek, Irena; Dacevic, Mirjana; Grbic, Sandra; Parojcic, Jelena; Vucicevic, Katarina; Prostran, Milica; Miljkovic, Branislava

2012-04-01

The aim of this case study was to develop a drug-specific absorption model for levothyroxine (LT4) using mechanistic gastrointestinal simulation technology (GIST) implemented in the GastroPlus™ software package. The required input parameters were determined experimentally, in silico predicted and/or taken from the literature. The simulated plasma profile was similar and in a good agreement with the data observed in the in vivo bioequivalence study, indicating that the GIST model gave an accurate prediction of LT4 oral absorption. Additionally, plasma concentration-time profiles were simulated based on a set of experimental and virtual in vitro dissolution data in order to estimate the influence of different in vitro drug dissolution kinetics on the simulated plasma profiles and to identify biorelevant dissolution specification for LT4 immediate-release (IR) tablets. A set of experimental and virtual in vitro data was also used for correlation purposes. In vitro-in vivo correlation model based on the convolution approach was applied in order to assess the relationship between the in vitro and in vivo data. The obtained results suggest that dissolution specification of more than 85% LT4 dissolved in 60 min might be considered as biorelevant dissolution specification criteria for LT4 IR tablets. Copyright © 2012 John Wiley & Sons, Ltd.

Expanding Non-solenoidal Startup with Local Helicity Injection to Increased Toroidal Field and Helicity Injection Rate

NASA Astrophysics Data System (ADS)

Perry, J. M.; Barr, J. L.; Bodner, G. M.; Bongard, M. W.; Burke, M. G.; Fonck, R. J.; Hinson, E. T.; Lewicki, B. T.; Reusch, J. A.; Schlossberg, D. J.; Winz, G. R.

2015-11-01

Local helicity injection (LHI) is a non-solenoidal startup technique under development on the Pegasus ST. Plasma currents up to 0.18 MA have been initiated by LHI in conjunction with poloidal field induction. A 0-D power balance model has been developed to predict plasma current evolution by balancing helicity input against resistive dissipation. The model is being validated against a set of experimental measurements and magnetic reconstructions with radically varied plasma geometric evolutions. Outstanding physics issues with LHI startup are the scalings of confinement and MHD activity with helicity injection rate and toroidal field strength, as well as injector behavior at high field. Preliminary results from the newly-installed Thomson scattering system suggest core temperatures of a few hundred eV during LHI startup. Measurements are being expanded to multiple spatial points for ongoing confinement studies. A set of larger-area injectors is being installed in the lower divertor region, where increased toroidal field will provide a helicity injection rate over 3 times that of outboard injectors. In this regime helicity injection will be the dominant current drive. Experiments with divertor injectors will permit experimental differentiation of several possible confinement models, and demonstrate the feasibility of LHI startup at high field. Work supported by US DOE grant DE-FG02-96ER54375.

Effective utilization of ozone in plasma-based advanced oxidation process

NASA Astrophysics Data System (ADS)

Takeuchi, Nozomi; Ishibashi, Naoto; Sugiyama, Tsuyoshi; Kim, Hyun-Ha

2018-05-01

Decomposition of acetic acid in water was conducted using multiple plasmas generated within oxygen bubbles. Ballast capacitors were used to control the plasma input power, allowing hydrogen peroxide and ozone to be produced at different rates in each plasma by adjusting the capacitance. By using an ozone absorber connected to the plasma reactor, OH radicals, both generated by the plasmas directly and reproduced from hydrogen peroxide through reactions with ozone, could be effectively utilized for the reduction of total organic carbon (TOC). Under the condition with the highest ozone production rate, higher processing speed and energy efficiency for the TOC reduction were achieved compared with other plasma methods.

Neural network based glucose - insulin metabolism models for children with Type 1 diabetes.

PubMed

Mougiakakou, Stavroula G; Prountzou, Aikaterini; Iliopoulou, Dimitra; Nikita, Konstantina S; Vazeou, Andriani; Bartsocas, Christos S

2006-01-01

In this paper two models for the simulation of glucose-insulin metabolism of children with Type 1 diabetes are presented. The models are based on the combined use of Compartmental Models (CMs) and artificial Neural Networks (NNs). Data from children with Type 1 diabetes, stored in a database, have been used as input to the models. The data are taken from four children with Type 1 diabetes and contain information about glucose levels taken from continuous glucose monitoring system, insulin intake and food intake, along with corresponding time. The influences of taken insulin on plasma insulin concentration, as well as the effect of food intake on glucose input into the blood from the gut, are estimated from the CMs. The outputs of CMs, along with previous glucose measurements, are fed to a NN, which provides short-term prediction of glucose values. For comparative reasons two different NN architectures have been tested: a Feed-Forward NN (FFNN) trained with the back-propagation algorithm with adaptive learning rate and momentum, and a Recurrent NN (RNN), trained with the Real Time Recurrent Learning (RTRL) algorithm. The results indicate that the best prediction performance can be achieved by the use of RNN.

Quantification of Dynamic 11C-Phenytoin PET Studies.

PubMed

Mansor, Syahir; Boellaard, Ronald; Froklage, Femke E; Bakker, Esther D M; Yaqub, Maqsood; Voskuyl, Rob A; Schwarte, Lothar A; Verbeek, Joost; Windhorst, Albert D; Lammertsma, Adriaan

2015-09-01

The overexpression of P-glycoprotein (Pgp) is thought to be an important mechanism of pharmacoresistance in epilepsy. Recently, (11)C-phenytoin has been evaluated preclinically as a tracer for Pgp. The aim of the present study was to assess the optimal plasma kinetic model for quantification of (11)C-phenytoin studies in humans. Dynamic (11)C-phenytoin PET scans of 6 healthy volunteers with arterial sampling were acquired twice on the same day and analyzed using single- and 2-tissue-compartment models with and without a blood volume parameter. Global and regional test-retest (TRT) variability was determined for both plasma to tissue rate constant (K1) and volume of distribution (VT). According to the Akaike information criterion, the reversible single-tissue-compartment model with blood volume parameter was the preferred plasma input model. Mean TRT variability ranged from 1.5% to 16.9% for K1 and from 0.5% to 5.8% for VT. Larger volumes of interest showed better repeatabilities than smaller regions. A 45-min scan provided essentially the same K1 and VT values as a 60-min scan. A reversible single-tissue-compartment model with blood volume seems to be a good candidate model for quantification of dynamic (11)C-phenytoin studies. Scan duration may be reduced to 45 min without notable loss of accuracy and precision of both K1 and VT, although this still needs to be confirmed under pathologic conditions. © 2015 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

A new free and open source tool for space plasma modeling.

NASA Astrophysics Data System (ADS)

Honkonen, I. J.

2014-12-01

I will present a new distributed memory parallel, free and open source computational model for studying space plasma. The model is written in C++ with emphasis on good software development practices and code readability without sacrificing serial or parallel performance. As such the model could be especially useful for education, for learning both (magneto)hydrodynamics (MHD) and computational model development. By using latest features of the C++ standard (2011) it has been possible to develop a very modular program which improves not only the readability of code but also the testability of the model and decreases the effort required to make changes to various parts of the program. Major parts of the model, functionality not directly related to (M)HD, have been outsourced to other freely available libraries which has reduced the development time of the model significantly. I will present an overview of the code architecture as well as details of different parts of the model and will show examples of using the model including preparing input files and plotting results. A multitude of 1-, 2- and 3-dimensional test cases are included in the software distribution and the results of, for example, Kelvin-Helmholtz, bow shock, blast wave and reconnection tests, will be presented.

Understanding rotation profile structures in ECH-heated plasmas using nonlinear gyrokinetic simulations

NASA Astrophysics Data System (ADS)

Wang, Weixing; Brian, B.; Ethier, S.; Chen, J.; Startsev, E.; Diamond, P. H.; Lu, Z.

2015-11-01

A non-diffusive momentum flux connecting edge momentum sources/sinks and core plasma flow is required to establish the off-axis peaked ion rotation profile typically observed in ECH-heated DIII-D plasmas without explicit external momentum input. The understanding of the formation of such profile structures provides an outstanding opportunity to test the physics of turbulence driving intrinsic rotation, and validate first-principles-based gyrokinetic simulation models. Nonlinear, global gyrokinetic simulations of DIII-D ECH plasmas indicate a substantial ITG fluctuation-induced residual stress generated around the region of peaked toroidal rotation, along with a diffusive momentum flux. The residual stress profile shows an anti-gradient, dipole structure, which is critical for accounting for the formation of the peaked rotation profile. It is showed that both turbulence intensity gradient and zonal flow ExB shear contribute to the generation of k// asymmetry needed for residual stress generation. By balancing the simulated residual stress and the momentum diffusion, a rotation profile is calculated. In general, the radial structure of core rotation profile is largely determined by the residual stress profile, while the amplitude of core rotation depends on the edge toroidal rotation velocity, which is determined by edge physics and used as a boundary condition in our model. The calculated core rotation profile is consistent with the experimental measurements. Also discussed is the modification of turbulence-generated Reynolds stress on poloidal rotation in those plasmas. Work supported by U.S. DOE Contract DE-AC02-09-CH11466.

Plasma arc welding repair of space flight hardware

NASA Technical Reports Server (NTRS)

Hoffman, David S.

1993-01-01

Repair and refurbishment of flight and test hardware can extend the useful life of very expensive components. A technique to weld repair the main combustion chamber of space shuttle main engines has been developed. The technique uses the plasma arc welding process and active cooling to seal cracks and pinholes in the hot-gas wall of the main combustion chamber liner. The liner hot-gas wall is made of NARloyZ, a copper alloy previously thought to be unweldable using conventional arc welding processes. The process must provide extensive heat input to melt the high conductivity NARloyZ while protecting the delicate structure of the surrounding material. The higher energy density of the plasma arc process provides the necessary heat input while active water cooling protects the surrounding structure. The welding process is precisely controlled using a computerized robotic welding system.

Intrinsic rotation from a residual stress at the boundary of a cylindrical laboratory plasma.

PubMed

Yan, Z; Xu, M; Diamond, P H; Holland, C; Müller, S H; Tynan, G R; Yu, J H

2010-02-12

An azimuthally symmetric radially sheared azimuthal flow is driven by a nondiffusive, or residual, turbulent stress localized to a narrow annular region at the boundary of a cylindrical magnetized helicon plasma device. A no-slip condition, imposed by ion-neutral flow damping outside the annular region, combined with a diffusive stress arising from turbulent and collisional viscous damping in the central plasma region, leads to net plasma rotation in the absence of momentum input.

Fully Parallel MHD Stability Analysis Tool

NASA Astrophysics Data System (ADS)

Svidzinski, Vladimir; Galkin, Sergei; Kim, Jin-Soo; Liu, Yueqiang

2015-11-01

Progress on full parallelization of the plasma stability code MARS will be reported. MARS calculates eigenmodes in 2D axisymmetric toroidal equilibria in MHD-kinetic plasma models. It is a powerful tool for studying MHD and MHD-kinetic instabilities and it is widely used by fusion community. Parallel version of MARS is intended for simulations on local parallel clusters. It will be an efficient tool for simulation of MHD instabilities with low, intermediate and high toroidal mode numbers within both fluid and kinetic plasma models, already implemented in MARS. Parallelization of the code includes parallelization of the construction of the matrix for the eigenvalue problem and parallelization of the inverse iterations algorithm, implemented in MARS for the solution of the formulated eigenvalue problem. Construction of the matrix is parallelized by distributing the load among processors assigned to different magnetic surfaces. Parallelization of the solution of the eigenvalue problem is made by repeating steps of the present MARS algorithm using parallel libraries and procedures. Results of MARS parallelization and of the development of a new fix boundary equilibrium code adapted for MARS input will be reported. Work is supported by the U.S. DOE SBIR program.

Development of flow separation control system to reduce the vibration of wind turbine blades

NASA Astrophysics Data System (ADS)

Kim, Ho-Young; Kim, Ho-Hyun; Han, Jong-Seob; Han, Jae-Hung

2017-04-01

The size of wind turbine blade has been continuously increased. Large-scale wind turbine blades induce loud noise, vibration; and maintenance difficulty is also increased. It causes the eventual increases of the cost of energy. The vibration of wind turbine blade is caused by several reasons such as a blade rotation, tower shadow, wind shear, and flow separation of a wind turbine blade. This wind speed variation changes in local angle of attack of the blades and create the vibration. The variation of local angle of attack influences the lift coefficient and causes the large change of the lift. In this study, we focus on the lift coefficient control using a flow control device to reduce the vibration. DU35-A15 airfoil was employed as baseline model. A plasma actuator was installed to generate the upwind jet in order to control the lift coefficient. Wind tunnel experiment was performed to demonstrate of the performance of the plasma actuator. The results show the plasma actuator can induce the flow separation compared with the baseline model. In addition, the actuator can delay the flow separation depending on the input AC frequency with the same actuator configuration.

The application of the large particles method of numerical modeling of the process of carbonic nanostructures synthesis in plasma

NASA Astrophysics Data System (ADS)

Abramov, G. V.; Gavrilov, A. N.

2018-03-01

The article deals with the numerical solution of the mathematical model of the particles motion and interaction in multicomponent plasma by the example of electric arc synthesis of carbon nanostructures. The high order of the particles and the number of their interactions requires a significant input of machine resources and time for calculations. Application of the large particles method makes it possible to reduce the amount of computation and the requirements for hardware resources without affecting the accuracy of numerical calculations. The use of technology of GPGPU parallel computing using the Nvidia CUDA technology allows organizing all General purpose computation on the basis of the graphical processor graphics card. The comparative analysis of different approaches to parallelization of computations to speed up calculations with the choice of the algorithm in which to calculate the accuracy of the solution shared memory is used. Numerical study of the influence of particles density in the macro particle on the motion parameters and the total number of particle collisions in the plasma for different modes of synthesis has been carried out. The rational range of the coherence coefficient of particle in the macro particle is computed.

Pulsed plasma solid propellant microthruster for the synchronous meteorological satellite. Task 4: Engineering model fabrication and test report

NASA Technical Reports Server (NTRS)

Guman, W. J. (Editor)

1972-01-01

Two flight prototype solid propellant pulsed plasma microthruster propulsion systems for the SMS satellite were fabricated, assembled and tested. The propulsion system is a completely self contained system requiring only three electrical inputs to operate: a 29.4 volt power source, a 28 volt enable signal and a 50 millsec long command fire signal that can be applied at any rate from 50 ppm to 110 ppm. The thrust level can be varied over a range 2.2 to 1 at constant impulse bit amplitude. By controlling the duration of the 28 volt enable either steady state thrust or a series of discrete impulse bits can be generated. A new technique of capacitor charging was implemented to reduce high voltage stress on energy storage capacitors.

Synthesis of diamond films at low temperature and study of nonlinear dynamic synthesis process

NASA Astrophysics Data System (ADS)

Zhao, Qingxun; Shang, Yong; Dong, Lifang; Fu, Guangsheng; Yan, Zheng; Yang, Jingfa

2002-09-01

In this paper, the experimental synthesis of diamond films and optical emission spectroscopy (OES) of the gaseous phase species are studied in the range of substrate temperature from Ts = 300°C to 850°C. The high quality sub-microcrystalline diamond films are successfully deposited at substrate temperature (330 ≍ 340)°C by adopting glow plasma assisted hot filament chemical vapor deposition (GPCVD). For the first time, in situ OES is applied to diagnose weak signal of GPCVD system when CH4 and H2 are used as the input gas, and the reactive species are identified in diamond growth processes. A primary model of diamond films growing at low temperature is presented by studying dynamic behavior for nonequilibrium plasma reactions.

Vasopressin responses to unloading arterial baroreceptors during cardiac nerve blockade in conscious dogs

NASA Technical Reports Server (NTRS)

O'Donnell, C. P.; Keil, L. C.; Thrasher, T. N.

1992-01-01

We examined the relative contributions of afferent input from the heart and from arterial baroreceptors in the stimulation of arginine vasopressin (AVP) secretion in response to hypotension caused by thoracic inferior vena caval constriction (TIVCC). Afferent input from cardiac receptors was reversibly blocked by infusing 2% procaine into the pericardial space to anesthetize the cardiac nerves. Acute cardiac nerve blockade (CNB) alone caused a rise in mean arterial pressure (MAP) of 24 +/- 3 mmHg but no change in plasma AVP. If the rise in MAP was prevented by TIVCC, plasma AVP increased by 39 +/- 15 pg/ml, and if MAP was allowed to increase and then was forced back to control by TIVCC, plasma AVP increased by 34 +/- 15 pg/ml. Thus the rise in MAP during CNB stimulated arterial baroreceptors, which in turn compensated for the loss of inhibitory input from cardiac receptors on AVP secretion. These results indicate that the maximum secretory response resulting from complete unloading of cardiac receptors at a normal MAP results in a mean increase in plasma AVP of 39 pg/ml in this group of dogs. When MAP was reduced 25% below control levels (from 95 +/- 5 to 69 +/- 3 mmHg) by TIVCC during pericardial saline infusion, plasma AVP increased by 79 +/- 42 pg/ml. However, the same degree of hypotension during CNB (MAP was reduced from 120 +/- 5 to 71 +/- 3 mmHg) led to a greater (P less than 0.05) increase in plasma AVP of 130 +/- 33 pg/ml. Because completely unloading cardiac receptors can account for an increase of only 39 pg/ml on average in this group of dogs, the remainder of the increase in plasma AVP must be due to other sources of stimulation. We suggest that the principal stimulus to AVP secretion after acute CNB in these studies arises from unloading the arterial baroreceptors.

Laser Pulse-Stretching Using Multiple Optical Ring-Cavities

NASA Technical Reports Server (NTRS)

Kojima, Jun; Nguyen, Quang-Viet; Lee, Chi-Ming (Technical Monitor)

2002-01-01

We describe a simple and passive nanosecond-long (ns-long) laser 'pulse-stretcher' using multiple optical ring-cavities. We present a model of the pulse-stretching process for an arbitrary number of optical ring-cavities. Using the model, we optimize the design of a pulse-stretcher for use in a spontaneous Raman scattering excitation system that avoids laser-induced plasma spark problems. From the optimized design, we then experimentally demonstrate and verify the model with a 3-cavity pulse-stretcher system that converts a 1000 mJ, 8.4 ns-long input laser pulse into an approximately 75 ns-long (FWHM) output laser pulse with a peak power reduction of 0.10X, and an 83% efficiency.

Solar wind driven empirical forecast models of the time derivative of the ground magnetic field

NASA Astrophysics Data System (ADS)

Wintoft, Peter; Wik, Magnus; Viljanen, Ari

2015-03-01

Empirical models are developed to provide 10-30-min forecasts of the magnitude of the time derivative of local horizontal ground geomagnetic field (|dBh/dt|) over Europe. The models are driven by ACE solar wind data. A major part of the work has been devoted to the search and selection of datasets to support the model development. To simplify the problem, but at the same time capture sudden changes, 30-min maximum values of |dBh/dt| are forecast with a cadence of 1 min. Models are tested both with and without the use of ACE SWEPAM plasma data. It is shown that the models generally capture sudden increases in |dBh/dt| that are associated with sudden impulses (SI). The SI is the dominant disturbance source for geomagnetic latitudes below 50° N and with minor contribution from substorms. However, at occasions, large disturbances can be seen associated with geomagnetic pulsations. For higher latitudes longer lasting disturbances, associated with substorms, are generally also captured. It is also shown that the models using only solar wind magnetic field as input perform in most cases equally well as models with plasma data. The models have been verified using different approaches including the extremal dependence index which is suitable for rare events.

Advanced simulation of mixed-material erosion/evolution and application to low and high-Z containing plasma facing components

NASA Astrophysics Data System (ADS)

Brooks, J. N.; Hassanein, A.; Sizyuk, T.

2013-07-01

Plasma interactions with mixed-material surfaces are being analyzed using advanced modeling of time-dependent surface evolution/erosion. Simulations use the REDEP/WBC erosion/redeposition code package coupled to the HEIGHTS package ITMC-DYN mixed-material formation/response code, with plasma parameter input from codes and data. We report here on analysis for a DIII-D Mo/C containing tokamak divertor. A DIII-D/DiMES probe experiment simulation predicts that sputtered molybdenum from a 1 cm diameter central spot quickly saturates (˜4 s) in the 5 cm diameter surrounding carbon probe surface, with subsequent re-sputtering and transport to off-probe divertor regions, and with high (˜50%) redeposition on the Mo spot. Predicted Mo content in the carbon agrees well with post-exposure probe data. We discuss implications and mixed-material analysis issues for Be/W mixing at the ITER outer divertor, and Li, C, Mo mixing at an NSTX divertor.

Study of BenW (n = 1-12) clusters: An electron collision perspective

NASA Astrophysics Data System (ADS)

Modak, Paresh; Kaur, Jaspreet; Antony, Bobby

2017-08-01

This article explores electron scattering cross sections by Beryllium-Tungsten clusters (BenW). Beryllium and tungsten are important elements for plasma facing wall components, especially for the deuterium/tritium phase of ITER and in the recently installed JET. The present study focuses on different electron impact interactions in terms of elastic cross section (Qel), inelastic cross section (Qinel), ionization cross section (Qion), and momentum transfer cross section (Qmtcs) for the first twelve clusters belonging to the BenW family. It also predicts the evolution of the cross section with the size of the cluster. These cross sections are used as an input to model processes in plasma. The ionization cross section presented here is compared with the available reported data. This is the first comprehensive report on cross section data for all the above-mentioned scattering channels, to the best of our knowledge. Such broad analysis of cross section data gives vital insight into the study of local chemistry of electron interactions with BenW (n = 1-12) clusters in plasma.

Evaluation of oxygen species during E-H transition in inductively coupled RF plasmas: combination of experimental results with global model

NASA Astrophysics Data System (ADS)

Meichsner, Jürgen; Wegner, Thomas

2018-05-01

Inductively coupled RF plasmas (ICP) in oxygen at low pressure have been intensively studied as a molecular and electronegative model system in the last funding period of the Collaborative Research Centre 24 "Fundamentals of Complex Plasmas". The ICP configuration consists of a planar coil inside a quartz cylinder as dielectric barrier which is immersed in a large stainless steel vacuum chamber. In particular, the E-H mode transition has been investigated, combining experimental results from comprehensive plasma diagnostics as input for analytical rate equation calculation of a volume averaged global model. The averaged density was determined for electrons, negative ions O-, molecular oxygen ground state O2(X3 Σg-) and singlet metastable state O2(a1 Δg) from line-integrated measurements using 160 GHz Gaussian beam microwave interferometry coupled with laser photodetachment experiment and VUV absorption spectroscopy, respectively. Taking into account the relevant elementary processes and rate coefficients from literature together with the measured temperatures and averaged density of electrons, O2(X3 Σg-) and O2(a1 Δg) the steady state density was calculated for O(3P), O2(b1 Σg+), O(1D), O(1S), O3, O-, O2-, and O3-, respectively. The averaged density of negative ions O- from the rate equation calculation is compared with the measured one. The normalized source and loss rates are discussed for O(3P), O2(b1 Σg+) and O-. Contribution to the Topical Issue "Fundamentals of Complex Plasmas", edited by Jürgen Meichsner, Michael Bonitz, Holger Fehske, Alexander Piel.

Plasma gun with coaxial powder feed and adjustable cathode

NASA Technical Reports Server (NTRS)

Zaplatynsky, Isidor (Inventor)

1991-01-01

An improved plasma gun coaxially injects particles of ceramic materials having high melting temperatures into the central portion of a plasma jet. This results in a more uniform and higher temperature and velocity distribution of the sprayed particles. The position of the cathode is adjustable to facilitate optimization of the performance of the gun wherein grains of the ceramic material are melted at lower power input levels.

Comparative study of INPIStron and spark gap

NASA Technical Reports Server (NTRS)

Han, Kwang S.; Lee, Ja H.

1993-01-01

An inverse pinch plasma switch, INPIStron, was studied in comparison to a conventional spark gap. The INPIStron is under development for high power switching applications. The INPIStron has an inverse pinch dynamics, opposed to Z-pinch dynamics in the spark gap. The electrical, plasma dynamics and radiative properties of the closing plasmas have been studied. Recently the high-voltage pulse transfer capabilities or both the INPIStron and the spark gap were also compared. The INPIStron with a low impedance Z = 9 ohms transfers 87 percent of an input pulse with a halfwidth of 2 mu s. For the same input pulse the spark gap of Z = 100 ohms transfers 68 percent. Fast framing and streak photography, taken with an TRW image converter camera, was used to observe the discharge uniformity and closing plasma speed in both switches. In order to assess the effects of closing plasmas on erosion of electrode material, emission spectra of two switches were studied with a spectrometer-optical multi channel analyzer (OMA) system. The typical emission spectra of the closing plasmas in the INPIStron and the spark gap showed that there were comparatively weak carbon line emission in 658.7 nm and copper (electrode material) line emissions in the INPIStron, indicating low erosion of materials in the INPIStron.

Integrated Computer Controlled Glow Discharge Tube

NASA Astrophysics Data System (ADS)

Kaiser, Erik; Post-Zwicker, Andrew

2002-11-01

An "Interactive Plasma Display" was created for the Princeton Plasma Physics Laboratory to demonstrate the characteristics of plasma to various science education outreach programs. From high school students and teachers, to undergraduate students and visitors to the lab, the plasma device will be a key component in advancing the public's basic knowledge of plasma physics. The device is fully computer controlled using LabVIEW, a touchscreen Graphical User Interface [GUI], and a GPIB interface. Utilizing a feedback loop, the display is fully autonomous in controlling pressure, as well as in monitoring the safety aspects of the apparatus. With a digital convectron gauge continuously monitoring pressure, the computer interface analyzes the input signals, while making changes to a digital flow controller. This function works independently of the GUI, allowing the user to simply input and receive a desired pressure; quickly, easily, and intuitively. The discharge tube is a 36" x 4"id glass cylinder with 3" side port. A 3000 volt, 10mA power supply, is used to breakdown the plasma. A 300 turn solenoid was created to demonstrate the magnetic pinching of a plasma. All primary functions of the device are controlled through the GUI digital controllers. This configuration allows for operators to safely control the pressure (100mTorr-1Torr), magnetic field (0-90Gauss, 7amps, 10volts), and finally, the voltage applied across the electrodes (0-3000v, 10mA).

A Plasma Display Terminal.

ERIC Educational Resources Information Center

Stifle, Jack

A graphics terminal designed for use as a remote computer input/output terminal is described. Although the terminal is intended for use in teaching applications, it has several features which make it useful in many other computer terminal applications. These features include: a 10-inch square plasma display panel, permanent storage of information…

Correlations between plasma variables and the deposition process of Si films from chlorosilanes in low pressure RF plasma of argon and hydrogen

NASA Technical Reports Server (NTRS)

Avni, R.; Carmi, U.; Grill, A.; Manory, R.; Grossman, E.

1984-01-01

The dissociation of chlorosilanes to silicon and its deposition on a solid substrate in a RF plasma of mixtures of argon and hydrogen were investigated as a function of the macrovariables of the plasma. The dissociation mechanism of chlorosilanes and HCl as well as the formation of Si in the plasma state were studied by sampling the plasma with a quadrupole mass spectrometer. Macrovariables such as pressure, net RF power input and locations in the plasma reactor strongly influence the kinetics of dissociation. The deposition process of microcrystalline silicon films and its chlorine contamination were correlated to the dissociation mechanism of chlorosilanes and HCl.

Quantification of Plasma miRNAs by Digital PCR for Cancer Diagnosis

PubMed Central

Ma, Jie; Li, Ning; Guarnera, Maria; Jiang, Feng

2013-01-01

Analysis of plasma microRNAs (miRNAs) by quantitative polymerase chain reaction (qPCR) provides a potential approach for cancer diagnosis. However, absolutely quantifying low abundant plasma miRNAs is challenging with qPCR. Digital PCR offers a unique means for assessment of nucleic acids presenting at low levels in plasma. This study aimed to evaluate the efficacy of digital PCR for quantification of plasma miRNAs and the potential utility of this technique for cancer diagnosis. We used digital PCR to quantify the copy number of plasma microRNA-21-5p (miR-21–5p) and microRNA-335–3p (miR-335–3p) in 36 lung cancer patients and 38 controls. Digital PCR showed a high degree of linearity and quantitative correlation with miRNAs in a dynamic range from 1 to 10,000 copies/μL of input, with high reproducibility. qPCR exhibited a dynamic range from 100 to 1×107 copies/μL of input. Digital PCR had a higher sensitivity to detect copy number of the miRNAs compared with qPCR. In plasma, digital PCR could detect copy number of both miR-21–5p and miR-335–3p, whereas qPCR was only able to assess miR-21–5p. Quantification of the plasma miRNAs by digital PCR provided 71.8% sensitivity and 80.6% specificity in distinguishing lung cancer patients from cancer-free subjects. PMID:24277982

The rectangular array of magnetic probes on J-TEXT tokamak.

PubMed

Chen, Zhipeng; Li, Fuming; Zhuang, Ge; Jian, Xiang; Zhu, Lizhi

2016-11-01

The rectangular array of magnetic probes system was newly designed and installed in the torus on J-TEXT tokamak to measure the local magnetic fields outside the last closed flux surface at a single toroidal angle. In the implementation, the experimental results agree well with the theoretical results based on the Spool model and three-dimensional numerical finite element model when the vertical field was applied. Furthermore, the measurements were successfully used as the input of EFIT code to conduct the plasma equilibrium reconstruction. The calculated Faraday rotation angle using the EFIT output is in agreement with the measured one from the three-wave polarimeter-interferometer system.

The rectangular array of magnetic probes on J-TEXT tokamak

NASA Astrophysics Data System (ADS)

Chen, Zhipeng; Li, Fuming; Zhuang, Ge; Jian, Xiang; Zhu, Lizhi

2016-11-01

The rectangular array of magnetic probes system was newly designed and installed in the torus on J-TEXT tokamak to measure the local magnetic fields outside the last closed flux surface at a single toroidal angle. In the implementation, the experimental results agree well with the theoretical results based on the Spool model and three-dimensional numerical finite element model when the vertical field was applied. Furthermore, the measurements were successfully used as the input of EFIT code to conduct the plasma equilibrium reconstruction. The calculated Faraday rotation angle using the EFIT output is in agreement with the measured one from the three-wave polarimeter-interferometer system.

Identification of individualised empirical models of carbohydrate and insulin effects on T1DM blood glucose dynamics

NASA Astrophysics Data System (ADS)

Cescon, Marzia; Johansson, Rolf; Renard, Eric; Maran, Alberto

2014-07-01

One of the main limiting factors in improving glucose control for type 1 diabetes mellitus (T1DM) subjects is the lack of a precise description of meal and insulin intake effects on blood glucose. Knowing the magnitude and duration of such effects would be useful not only for patients and physicians, but also for the development of a controller targeting glycaemia regulation. Therefore, in this paper we focus on estimating low-complexity yet physiologically sound and individualised multi-input single-output (MISO) models of the glucose metabolism in T1DM able to reflect the basic dynamical features of the glucose-insulin metabolic system in response to a meal intake or an insulin injection. The models are continuous-time second-order transfer functions relating the amount of carbohydrate of a meal and the insulin units of the accordingly administered dose (inputs) to plasma glucose evolution (output) and consist of few parameters clinically relevant to be estimated. The estimation strategy is continuous-time data-driven system identification and exploits a database in which meals and insulin boluses are separated in time, allowing the unique identification of the model parameters.

Neutron monitoring and electrode calorimetry experiments in the HIP-1 Hot Ion Plasma

NASA Technical Reports Server (NTRS)

Reinmann, J. J.; Layman, R. W.

1977-01-01

Results are presented for two diagnostic procedures on HIP-1: neutron diagnostics to determine where neutrons originated within the plasma discharge chamber and electrode calorimetry to measure the steady-state power absorbed by the two anodes and cathodes. Results are also reported for a hot-ion plasma formed with a continuous-cathode rod, one that spans the full length of the test section, in place of the two hollow cathodes. The outboard neutron source strength increased relative to that at the midplane when (1) the cathode tips were moved farther outboard, (2) the anode diameters were increased, and (3) one of the anodes was removed. The distribution of neutron sources within the plasma discharge chamber was insensitive to the division of current between the two cathodes. For the continuous cathode, increasing the discharge current increased the midplane neutron source strength relative to the outboard source strength. Each cathode absorbed from 12 to 15 percent of the input power regardless of the division of current between the cathodes. The anodes absorbed from 20 to 40 percent of the input power. The division of power absorption between the anodes varied with plasma operating conditions and electrode placement.

Development of Simple Designs of Multitip Probe Diagnostic Systems for RF Plasma Characterization

PubMed Central

Naz, M. Y.; Shukrullah, S.; Ghaffar, A.; Rehman, N. U.

2014-01-01

Multitip probes are very useful diagnostics for analyzing and controlling the physical phenomena occurring in low temperature discharge plasmas. However, DC biased probes often fail to perform well in processing plasmas. The objective of the work was to deduce simple designs of DC biased multitip probes for parametric study of radio frequency plasmas. For this purpose, symmetric double probe, asymmetric double probe, and symmetric triple probe diagnostic systems and their driving circuits were designed and tested in an inductively coupled plasma (ICP) generated by a 13.56 MHz radio frequency (RF) source. Using I-V characteristics of these probes, electron temperature, electron number density, and ion saturation current was measured as a function of input power and filling gas pressure. An increasing trend was noticed in electron temperature and electron number density for increasing input RF power whilst a decreasing trend was evident in these parameters when measured against filling gas pressure. In addition, the electron energy probability function (EEPF) was also studied by using an asymmetric double probe. These studies confirmed the non-Maxwellian nature of the EEPF and the presence of two groups of the energetic electrons at low filling gas pressures. PMID:24683326

Clinical and Genetic Determinants of Warfarin Pharmacokinetics and Pharmacodynamics during Treatment Initiation

PubMed Central

Gong, Inna Y.; Schwarz, Ute I.; Crown, Natalie; Dresser, George K.; Lazo-Langner, Alejandro; Zou, GuangYong; Roden, Dan M.; Stein, C. Michael; Rodger, Marc; Wells, Philip S.; Kim, Richard B.; Tirona, Rommel G.

2011-01-01

Variable warfarin response during treatment initiation poses a significant challenge to providing optimal anticoagulation therapy. We investigated the determinants of initial warfarin response in a cohort of 167 patients. During the first nine days of treatment with pharmacogenetics-guided dosing, S-warfarin plasma levels and international normalized ratio were obtained to serve as inputs to a pharmacokinetic-pharmacodynamic (PK-PD) model. Individual PK (S-warfarin clearance) and PD (Imax) parameter values were estimated. Regression analysis demonstrated that CYP2C9 genotype, kidney function, and gender were independent determinants of S-warfarin clearance. The values for Imax were dependent on VKORC1 and CYP4F2 genotypes, vitamin K status (as measured by plasma concentrations of proteins induced by vitamin K absence, PIVKA-II) and weight. Importantly, indication for warfarin was a major independent determinant of Imax during initiation, where PD sensitivity was greater in atrial fibrillation than venous thromboembolism. To demonstrate the utility of the global PK-PD model, we compared the predicted initial anticoagulation responses with previously established warfarin dosing algorithms. These insights and modeling approaches have application to personalized warfarin therapy. PMID:22114699

Local and integral disruption forces on the tokamak wall

NASA Astrophysics Data System (ADS)

Pustovitov, V. D.; Kiramov, D. I.

2018-04-01

The disruption-induced forces on the tokamak wall are evaluated analytically within the standard large-aspect-ratio model that implies axisymmetry, circular plasma and wall, and absence of halo currents. Additionally, the ideal-wall reaction is assumed. The disruptions are modelled as rapid changes in the plasma pressure (thermal quench (TQ)) and net current (current quench (CQ)). The force distribution over the poloidal angle is found as a function of these inputs. The derived formulas allow comparison of the TQ- and CQ-produced forces calculated differently, with and without account of the poloidal current induced in the wall. The latter variant represents the inherent property of the codes treating the wall as a set of toroidal filaments. It is proved here that such a simplification leads to unacceptably large errors in the simulated forces for both TQs and CQs. It is also shown that the TQ part of the force must prevail over that due to CQ in the high-β scenarios developed for JT-60SA and ITER.

Numerical simulations of flares on M dwarf stars. I - Hydrodynamics and coronal X-ray emission

NASA Technical Reports Server (NTRS)

Cheng, Chung-Chieh; Pallavicini, Roberto

1991-01-01

Flare-loop models are utilized to simulate the time evolution and physical characteristics of stellar X-ray flares by varying the values of flare-energy input and loop parameters. The hydrodynamic evolution is studied in terms of changes in the parameters of the mass, energy, and momentum equations within an area bounded by the chromosphere and the corona. The zone supports a magnetically confined loop for which processes are described including the expansion of heated coronal gas, chromospheric evaporation, and plasma compression at loop footpoints. The intensities, time profiles, and average coronal temperatures of X-ray flares are derived from the simulations and compared to observational evidence. Because the amount of evaporated material does not vary linearly with flare-energy input, large loops are required to produce the energy measured from stellar flares.

Wave Modeling of the Solar Wind.

PubMed

Ofman, Leon

The acceleration and heating of the solar wind have been studied for decades using satellite observations and models. However, the exact mechanism that leads to solar wind heating and acceleration is poorly understood. In order to improve the understanding of the physical mechanisms that are involved in these processes a combination of modeling and observational analysis is required. Recent models constrained by satellite observations show that wave heating in the low-frequency (MHD), and high-frequency (ion-cyclotron) range may provide the necessary momentum and heat input to coronal plasma and produce the solar wind. This review is focused on the results of several recent solar modeling studies that include waves explicitly in the MHD and the kinetic regime. The current status of the understanding of the solar wind acceleration and heating by waves is reviewed.

Megawatt Electromagnetic Plasma Propulsion

NASA Technical Reports Server (NTRS)

Gilland, James; Lapointe, Michael; Mikellides, Pavlos

2003-01-01

The NASA Glenn Research Center program in megawatt level electric propulsion is centered on electromagnetic acceleration of quasi-neutral plasmas. Specific concepts currently being examined are the Magnetoplasmadynamic (MPD) thruster and the Pulsed Inductive Thruster (PIT). In the case of the MPD thruster, a multifaceted approach of experiments, computational modeling, and systems-level models of self field MPD thrusters is underway. The MPD thruster experimental research consists of a 1-10 MWe, 2 ms pulse-forming-network, a vacuum chamber with two 32 diffusion pumps, and voltage, current, mass flow rate, and thrust stand diagnostics. Current focus is on obtaining repeatable thrust measurements of a Princeton Benchmark type self field thruster operating at 0.5-1 gls of argon. Operation with hydrogen is the ultimate goal to realize the increased efficiency anticipated using the lighter gas. Computational modeling is done using the MACH2 MHD code, which can include real gas effects for propellants of interest to MPD operation. The MACH2 code has been benchmarked against other MPD thruster data, and has been used to create a point design for a 3000 second specific impulse (Isp) MPD thruster. This design is awaiting testing in the experimental facility. For the PIT, a computational investigation using MACH2 has been initiated, with experiments awaiting further funding. Although the calculated results have been found to be sensitive to the initial ionization assumptions, recent results have agreed well with experimental data. Finally, a systems level self-field MPD thruster model has been developed that allows for a mission planner or system designer to input Isp and power level into the model equations and obtain values for efficiency, mass flow rate, and input current and voltage. This model emphasizes algebraic simplicity to allow its incorporation into larger trajectory or system optimization codes. The systems level approach will be extended to the pulsed inductive thruster and other electrodeless thrusters at a future date.

Prediction of Welded Joint Strength in Plasma Arc Welding: A Comparative Study Using Back-Propagation and Radial Basis Neural Networks

NASA Astrophysics Data System (ADS)

Srinivas, Kadivendi; Vundavilli, Pandu R.; Manzoor Hussain, M.; Saiteja, M.

2016-09-01

Welding input parameters such as current, gas flow rate and torch angle play a significant role in determination of qualitative mechanical properties of weld joint. Traditionally, it is necessary to determine the weld input parameters for every new welded product to obtain a quality weld joint which is time consuming. In the present work, the effect of plasma arc welding parameters on mild steel was studied using a neural network approach. To obtain a response equation that governs the input-output relationships, conventional regression analysis was also performed. The experimental data was constructed based on Taguchi design and the training data required for neural networks were randomly generated, by varying the input variables within their respective ranges. The responses were calculated for each combination of input variables by using the response equations obtained through the conventional regression analysis. The performances in Levenberg-Marquardt back propagation neural network and radial basis neural network (RBNN) were compared on various randomly generated test cases, which are different from the training cases. From the results, it is interesting to note that for the above said test cases RBNN analysis gave improved training results compared to that of feed forward back propagation neural network analysis. Also, RBNN analysis proved a pattern of increasing performance as the data points moved away from the initial input values.

Studies of RF sheaths and diagnostics on IShTAR

DOE Office of Scientific and Technical Information (OSTI.GOV)

Crombé, K., E-mail: Kristel.Crombe@UGent.be; LPP-ERM/KMS, Royal Military Academy, Brussels; Devaux, S.

2015-12-10

IShTAR (Ion cyclotron Sheath Test ARrangement) is a linear magnetised plasma test facility for RF sheaths studies at the Max-Planck-Institut für Plasmaphysik in Garching. In contrast to a tokamak, a test stand provides more liberty to impose the parameters and gives better access for the instrumentation and antennas. The project will support the development of diagnostic methods for characterising RF sheaths and validate and improve theoretical predictions. The cylindrical vacuum vessel has a diameter of 1 m and is 1.1 m long. The plasma is created by an external cylindrical plasma source equipped with a helical antenna that has been designed tomore » excite the m=1 helicon mode. In inductive mode, plasma densities and electron temperatures have been characterised with a planar Langmuir probe as a function of gas pressure and input RF power. A 2D array of RF compensated Langmuir probes and a spectrometer are planned. A single strap RF antenna has been designed; the plasma-facing surface is aligned to the cylindrical plasma to ease the modelling. The probes will allow direct measurements of plasma density profiles in front of the RF antenna, and thus a detailed study of the density modifications induced by RF sheaths, which influences the coupling. The RF antenna frequency has been chosen to study different plasma wave interactions: the accessible plasma density range includes an evanescent and propagative behaviour of slow or fast waves, and allows the study of the effect of the lower hybrid resonance layer.« less

Population pharmacokinetic modelling of tramadol using inverse Gaussian function for the assessment of drug absorption from prolonged and immediate release formulations.

PubMed

Brvar, Nina; Mateović-Rojnik, Tatjana; Grabnar, Iztok

2014-10-01

This study aimed to develop a population pharmacokinetic model for tramadol that combines different input rates with disposition characteristics. Data used for the analysis were pooled from two phase I bioavailability studies with immediate (IR) and prolonged release (PR) formulations in healthy volunteers. Tramadol plasma concentration-time data were described by an inverse Gaussian function to model the complete input process linked to a two-compartment disposition model with first-order elimination. Although polymorphic CYP2D6 appears to be a major enzyme involved in the metabolism of tramadol, application of a mixture model to test the assumption of two and three subpopulations did not reveal any improvement of the model. The final model estimated parameters with reasonable precision and was able to estimate the interindividual variability of all parameters except for the relative bioavailability of PR vs. IR formulation. Validity of the model was further tested using the nonparametric bootstrap approach. Finally, the model was applied to assess absorption kinetics of tramadol and predict steady-state pharmacokinetics following administration of both types of formulations. For both formulations, the final model yielded a stable estimate of the absorption time profiles. Steady-state simulation supports switching of patients from IR to PR formulation. Copyright © 2014 Elsevier B.V. All rights reserved.

A curve-fitting approach to estimate the arterial plasma input function for the assessment of glucose metabolic rate and response to treatment.

PubMed

Vriens, Dennis; de Geus-Oei, Lioe-Fee; Oyen, Wim J G; Visser, Eric P

2009-12-01

For the quantification of dynamic (18)F-FDG PET studies, the arterial plasma time-activity concentration curve (APTAC) needs to be available. This can be obtained using serial sampling of arterial blood or an image-derived input function (IDIF). Arterial sampling is invasive and often not feasible in practice; IDIFs are biased because of partial-volume effects and cannot be used when no large arterial blood pool is in the field of view. We propose a mathematic function, consisting of an initial linear rising activity concentration followed by a triexponential decay, to describe the APTAC. This function was fitted to 80 oncologic patients and verified for 40 different oncologic patients by area-under-the-curve (AUC) comparison, Patlak glucose metabolic rate (MR(glc)) estimation, and therapy response monitoring (Delta MR(glc)). The proposed function was compared with the gold standard (serial arterial sampling) and the IDIF. To determine the free parameters of the function, plasma time-activity curves based on arterial samples in 80 patients were fitted after normalization for administered activity (AA) and initial distribution volume (iDV) of (18)F-FDG. The medians of these free parameters were used for the model. In 40 other patients (20 baseline and 20 follow-up dynamic (18)F-FDG PET scans), this model was validated. The population-based curve, individually calibrated by AA and iDV (APTAC(AA/iDV)), by 1 late arterial sample (APTAC(1 sample)), and by the individual IDIF (APTAC(IDIF)), was compared with the gold standard of serial arterial sampling (APTAC(sampled)) using the AUC. Additionally, these 3 methods of APTAC determination were evaluated with Patlak MR(glc) estimation and with Delta MR(glc) for therapy effects using serial sampling as the gold standard. Excellent individual fits to the function were derived with significantly different decay constants (P < 0.001). Correlations between AUC from APTAC(AA/iDV), APTAC(1 sample), and APTAC(IDIF) with the gold standard (APTAC(sampled)) were 0.880, 0.994, and 0.856, respectively. For MR(glc), these correlations were 0.963, 0.994, and 0.966, respectively. In response monitoring, these correlations were 0.947, 0.982, and 0.949, respectively. Additional scaling by 1 late arterial sample showed a significant improvement (P < 0.001). The fitted input function calibrated for AA and iDV performed similarly to IDIF. Performance improved significantly using 1 late arterial sample. The proposed model can be used when an IDIF is not available or when serial arterial sampling is not feasible.

The measurement of the intrinsic impurities of molybdenum and carbon in the Alcator C-Mod tokamak plasma using low resolution spectroscopy

NASA Astrophysics Data System (ADS)

May, M. J.; Finkenthal, M.; Regan, S. P.; Moos, H. W.; Terry, J. L.; Goetz, J. A.; Graf, M. A.; Rice, J. E.; Marmar, E. S.; Fournier, K. B.; Goldstein, W. H.

1997-06-01

The intrinsic impurity content of molybdenum and carbon was measured in the Alcator C-Mod tokamak using low resolution, multilayer mirror (MLM) spectroscopy ( Delta lambda ~1-10 AA). Molybdenum was the dominant high-Z impurity and originated from the molybdenum armour tiles covering all of the plasma facing surfaces (including the inner column, the poloidal divertor plates and the ion cyclotron resonant frequency (ICRF) limiter) at Alcator C-Mod. Despite the all metal first wall, a carbon concentration of 1 to 2% existed in the plasma and was the major low-Z impurity in Alcator C-Mod. Thus, the behaviour of intrinsic molybdenum and carbon penetrating into the main plasma and the effect on the plasma must be measured and characterized during various modes of Alcator C-Mod operation. To this end, soft X-ray extreme ultraviolet (XUV) emission lines of charge states, ranging from hydrogen-like to helium-like lines of carbon (radius/minor radius, r/a~1) at the plasma edge to potassium to chlorine-like (0.4

Experimental study of the visible-light photocatalytic activity of oxygen-deficient TiO2 prepared with Ar/H2 plasma surface treatment

NASA Astrophysics Data System (ADS)

Nakano, Takuma; Yazawa, Shota; Araki, Shota; Kogoshi, Sumio; Katayama, Noboru; Kudo, Yusuke; Nakanishi, Tetsuya

2015-01-01

Oxygen-deficient TiO2 (TiO2-x) has been proposed as a visible-light-responsive photocatalyst. TiO2-x thin films were prepared by Ar/H2 plasma surface treatment, applying varying levels of microwave input power and processing times. The highest visible light photocatalytic activity was observed when using an input power of 200 W, a plasma processing time of 10 min, and a 1:1 \\text{Ar}:\\text{H}2 ratio, conditions that generate an electron temperature of 5.7(±1.0) eV and an electron density of 8.5 × 1010 cm-3. The maximum formaldehyde (HCHO) removal rate of the TiO2-x film was 2.6 times higher than that obtained from a TiO2-xNx film under the same test conditions.

Adaptive plasma for cancer therapy: physics, mechanism and applications

NASA Astrophysics Data System (ADS)

Keidar, Michael

2017-10-01

One of the most promising applications of cold atmospheric plasma (CAP) is the cancer therapy. The uniqueness of plasma is in its ability to change composition in situ. Plasma self-organization could lead to formation of coherent plasma structures. These coherent structures tend to modulate plasma chemistry and composition, including reactive species, the electric field and charged particles. Formation of coherent plasma structures allows the plasma to adapt to external boundary conditions, such as different cells types and their contextual tissues. In this talk we will explore possibilities and opportunities that the adaptive plasma therapeutic system might offer. We shall define such an adaptive system as a plasma device that is able to adjust the plasma composition to obtain optimal desirable outcomes through its interaction with cells and tissues. The efficacy of cold plasma in a pre-clinical model of various cancer types such as lung, bladder, breast, head, neck, brain and skin has been demonstrated. Both in-vitro and in-vivo studies revealed that cold plasmas selectively kill cancer cells. Recently mechanism of plasma selectivity based on aquaporin hypothesis has been proposed. Aquaporins (AQPs) are the confirmed membrane channels of H2O2 and other large molecules. We have demonstrated that the anti-cancer capacity of plasma could be inhibited by silencing the expression of AQPs. Additional possible cell feedback mechanism was recently discovered. It is associated with production of reactive species during direct CAP treatment by cancer cells. Selective production of hydrogen peroxide by different cells can lead to adaptation of chemistry at the plasma-cell interface based on the cellular input. In particular we have found that the discharge voltage is an important factor affecting the ratio of reactive oxygen species to reactive nitrogen species in the gas phase and this correlates well with effect of hydrogen peroxide production by cells. This work was supported by a National Science Foundation, Grant No. 1465061.

Battery-powered pulsed high density inductively coupled plasma source for pre-ionization in laboratory astrophysics experiments.

PubMed

Chaplin, Vernon H; Bellan, Paul M

2015-07-01

An electrically floating radiofrequency (RF) pre-ionization plasma source has been developed to enable neutral gas breakdown at lower pressures and to access new experimental regimes in the Caltech laboratory astrophysics experiments. The source uses a customized 13.56 MHz class D RF power amplifier that is powered by AA batteries, allowing it to safely float at 3-6 kV with the electrodes of the high voltage pulsed power experiments. The amplifier, which is capable of 3 kW output power in pulsed (<1 ms) operation, couples electrical energy to the plasma through an antenna external to the 1.1 cm radius discharge tube. By comparing the predictions of a global equilibrium discharge model with the measured scalings of plasma density with RF power input and axial magnetic field strength, we demonstrate that inductive coupling (rather than capacitive coupling or wave damping) is the dominant energy transfer mechanism. Peak ion densities exceeding 5 × 10(19) m(-3) in argon gas at 30 mTorr have been achieved with and without a background field. Installation of the pre-ionization source on a magnetohydrodynamically driven jet experiment reduced the breakdown time and jitter and allowed for the creation of hotter, faster argon plasma jets than was previously possible.

Observation of turbulent-driven shear flow in a cylindrical laboratory plasma device.

PubMed

Holland, C; Yu, J H; James, A; Nishijima, D; Shimada, M; Taheri, N; Tynan, G R

2006-05-19

An azimuthally symmetric radially sheared plasma fluid flow is observed to spontaneously form in a cylindrical magnetized helicon plasma device with no external sources of momentum input. A turbulent momentum conservation analysis shows that this shear flow is sustained by the Reynolds stress generated by collisional drift turbulence in the device. The results provide direct experimental support for the basic theoretical picture of drift-wave-shear-flow interactions.

Experimental and numerical study on plasma nitriding of AISI P20 mold steel

NASA Astrophysics Data System (ADS)

Nayebpashaee, N.; Vafaeenezhad, H.; Kheirandish, Sh.; Soltanieh, M.

2016-09-01

In this study, plasma nitriding was used to fabricate a hard protective layer on AISI P20 steel, at three process temperatures (450°C, 500°C, and 550°C) and over a range of time periods (2.5, 5, 7.5, and 10 h), and at a fixed gas N2:H2 ratio of 75vol%:25vol%. The morphology of samples was studied using optical microscopy and scanning electron microscopy, and the formed phase of each sample was determined by X-ray diffraction. The elemental depth profile was measured by energy dispersive X-ray spectroscopy, wavelength dispersive spectroscopy, and glow dispersive spectroscopy. The hardness profile of the samples was identified, and the microhardness profile from the surface to the sample center was recorded. The results show that ɛ-nitride is the dominant species after carrying out plasma nitriding in all strategies and that the plasma nitriding process improves the hardness up to more than three times. It is found that as the time and temperature of the process increase, the hardness and hardness depth of the diffusion zone considerably increase. Furthermore, artificial neural networks were used to predict the effects of operational parameters on the mechanical properties of plastic mold steel. The plasma temperature, running time of imposition, and target distance to the sample surface were all used as network inputs; Vickers hardness measurements were given as the output of the model. The model accurately reproduced the experimental outcomes under different operational conditions; therefore, it can be used in the effective simulation of the plasma nitriding process in AISI P20 steel.

Emtricitabine Seminal Plasma and Blood Plasma Population Pharmacokinetics in HIV-Infected Men in the EVARIST ANRS-EP 49 Study

PubMed Central

Tréluyer, Jean-Marc; Illamola, Silvia M.; Bouazza, Naïm; Foissac, Frantz; De Sousa Mendes, Maïlys; Lui, Gabrielle; Chenevier-Gobeaux, Camille; Suzan-Monti, Marie; Rouzioux, Christine; Assoumou, Lambert; Viard, Jean-Paul; Hirt, Déborah; Urien, Saïk; Ghosn, Jade

2015-01-01

We aimed to describe blood plasma (BP) and seminal plasma (SP) pharmacokinetics of emtricitabine (FTC) in HIV-1-infected men, assess its penetration in the male genital tract, and evaluate its impact on seminal plasma HIV load (spVL) detection. Men from the EVARIST ANRS EP49 study receiving combined antiretroviral therapy with FTC and with suppressed BP viral load were included in the study. A total of 236 and 209 FTC BP and SP concentrations, respectively, were available. A population pharmacokinetic model was developed with Monolix 4.1.4. The impact of FTC seminal exposure on spVL detection was explored by receiver operating characteristic (ROC) curves and mixed-effects logistic regressions. FTC BP pharmacokinetics was described by a two-compartment model. The addition of an effect compartment with different input and output constants best described FTC SP pharmacokinetics. No covariates were found to explain the variability in SP. FTC exposures (area under the concentration-time curve from 0 to 24 h [AUC0–24]) were higher in SP than in BP (median AUC0–24, 38.04 and 12.95 mg · liter−1 · h, respectively). The median (range) SP-to-BP AUC0–24 ratio was 2.91 (0.84 to 10.08). Less than 1% of FTC AUC0–24 ratios were lower than 1. The impact of FTC SP AUC0–24 or FTC SP-to-BP AUC0–24 ratio on spVL detection was not significant (P = 0.943 or 0.893, respectively). This is the first population model describing FTC pharmacokinetics simultaneously in both BP and SP. FTC distributes well in the male genital tract with higher FTC concentrations in SP than in BP. FTC seminal plasma exposures were considered efficient in the majority of men. PMID:26282407

Novel high-frequency energy-efficient pulsed-dc generator for capacitively coupled plasma discharge

NASA Astrophysics Data System (ADS)

Mamun, Md Abdullah Al; Furuta, Hiroshi; Hatta, Akimitsu

2018-03-01

The circuit design, assembly, and operating tests of a high-frequency and high-voltage (HV) pulsed dc generator (PDG) for capacitively coupled plasma (CCP) discharge inside a vacuum chamber are reported. For capacitive loads, it is challenging to obtain sharp rectangular pulses with fast rising and falling edges, requiring intense current for quick charging and discharging. The requirement of intense current generally limits the pulse operation frequency. In this study, we present a new type of PDG consisting of a pair of half-resonant converters and a constant current-controller circuit connected with HV solid-state power switches that can deliver almost rectangular high voltage pulses with fast rising and falling edges for CCP discharge. A prototype of the PDG is assembled to modulate from a high-voltage direct current (HVdc) input into a pulsed HVdc output, while following an input pulse signal and a set current level. The pulse rise time and fall time are less than 500 ns and 800 ns, respectively, and the minimum pulse width is 1 µs. The maximum voltage for a negative pulse is 1000 V, and the maximum repetition frequency is 500 kHz. During the pulse on time, the plasma discharge current is controlled steadily at the set value. The half-resonant converters in the PDG perform recovery of the remaining energy from the capacitive load at every termination of pulse discharge. The PDG performed with a high energy efficiency of 85% from the HVdc input to the pulsed dc output at a repetition rate of 1 kHz and with stable plasma operation in various discharge conditions. The results suggest that the developed PDG can be considered to be more efficient for plasma processing by CCP.

Novel high-frequency energy-efficient pulsed-dc generator for capacitively coupled plasma discharge.

PubMed

Mamun, Md Abdullah Al; Furuta, Hiroshi; Hatta, Akimitsu

2018-03-01

The circuit design, assembly, and operating tests of a high-frequency and high-voltage (HV) pulsed dc generator (PDG) for capacitively coupled plasma (CCP) discharge inside a vacuum chamber are reported. For capacitive loads, it is challenging to obtain sharp rectangular pulses with fast rising and falling edges, requiring intense current for quick charging and discharging. The requirement of intense current generally limits the pulse operation frequency. In this study, we present a new type of PDG consisting of a pair of half-resonant converters and a constant current-controller circuit connected with HV solid-state power switches that can deliver almost rectangular high voltage pulses with fast rising and falling edges for CCP discharge. A prototype of the PDG is assembled to modulate from a high-voltage direct current (HVdc) input into a pulsed HVdc output, while following an input pulse signal and a set current level. The pulse rise time and fall time are less than 500 ns and 800 ns, respectively, and the minimum pulse width is 1 µs. The maximum voltage for a negative pulse is 1000 V, and the maximum repetition frequency is 500 kHz. During the pulse on time, the plasma discharge current is controlled steadily at the set value. The half-resonant converters in the PDG perform recovery of the remaining energy from the capacitive load at every termination of pulse discharge. The PDG performed with a high energy efficiency of 85% from the HVdc input to the pulsed dc output at a repetition rate of 1 kHz and with stable plasma operation in various discharge conditions. The results suggest that the developed PDG can be considered to be more efficient for plasma processing by CCP.

Comparison of pulsed corona plasma and pulsed electric fields for the decontamination of water containing Legionella pneumophila as model organism.

PubMed

Banaschik, Robert; Burchhardt, Gerhard; Zocher, Katja; Hammerschmidt, Sven; Kolb, Juergen F; Weltmann, Klaus-Dieter

2016-12-01

Pulsed corona plasma and pulsed electric fields were assessed for their capacity to kill Legionella pneumophila in water. Electrical parameters such as in particular dissipated energy were equal for both treatments. This was accomplished by changing the polarity of the applied high voltage pulses in a coaxial electrode geometry resulting in the generation of corona plasma or an electric field. For corona plasma, generated by high voltage pulses with peak voltages of +80kV, Legionella were completely killed, corresponding to a log-reduction of 5.4 (CFU/ml) after a treatment time of 12.5min. For the application of pulsed electric fields from peak voltages of -80kV a survival of log 2.54 (CFU/ml) was still detectable after this treatment time. Scanning electron microscopy images of L. pneumophila showed rupture of cells after plasma treatment. In contrast, the morphology of bacteria seems to be intact after application of pulsed electric fields. The more efficient killing for the same energy input observed for pulsed corona plasma is likely due to induced chemical processes and the generation of reactive species as indicated by the evolution of hydrogen peroxide. This suggests that the higher efficacy and efficiency of pulsed corona plasma is primarily associated with the combined effect of the applied electric fields and the promoted reaction chemistry. Copyright © 2016 Elsevier B.V. All rights reserved.

Velocity Space Evolution of Dayside Reconnection Outflow

NASA Astrophysics Data System (ADS)

Broll, J. M.; Fuselier, S. A.; Trattner, K. J.

2015-12-01

Magnetic reconnection is a universal phenomenon occurring when energy stored in a complicated magnetic field topology is released into the surrounding plasma as the field simplifies its configuration. At Earth's dayside magnetopause, reconnection is responsible for mass and energy input from the solar wind into the magnetosphere. We describe the evolution of the velocity-space evolution of plasma outflow from a dayside magnetic reconnection region. We analyze Cluster magnetopause crossings between 1 and 10 Earth radii from the reconnection X-line predicted by the maximum magnetic shear model. The effects of nonadiabatic processes, such as deformation of the profile due to finite-gyroradius-induced pitch-angle scattering and wave-particle interactions, are described. We compare observations and simulation results to describe the outflow evolution and infer the field-aligned distance between an observation and the reconnection site producing it.

Circadian control of the daily plasma glucose rhythm: an interplay of GABA and glutamate.

PubMed

Kalsbeek, Andries; Foppen, Ewout; Schalij, Ingrid; Van Heijningen, Caroline; van der Vliet, Jan; Fliers, Eric; Buijs, Ruud M

2008-09-15

The mammalian biological clock, located in the hypothalamic suprachiasmatic nuclei (SCN), imposes its temporal structure on the organism via neural and endocrine outputs. To further investigate SCN control of the autonomic nervous system we focused in the present study on the daily rhythm in plasma glucose concentrations. The hypothalamic paraventricular nucleus (PVN) is an important target area of biological clock output and harbors the pre-autonomic neurons that control peripheral sympathetic and parasympathetic activity. Using local administration of GABA and glutamate receptor (ant)agonists in the PVN at different times of the light/dark-cycle we investigated whether daily changes in the activity of autonomic nervous system contribute to the control of plasma glucose and plasma insulin concentrations. Activation of neuronal activity in the PVN of non-feeding animals, either by administering a glutamatergic agonist or a GABAergic antagonist, induced hyperglycemia. The effect of the GABA-antagonist was time dependent, causing increased plasma glucose concentrations only when administered during the light period. The absence of a hyperglycemic effect of the GABA-antagonist in SCN-ablated animals provided further evidence for a daily change in GABAergic input from the SCN to the PVN. On the other hand, feeding-induced plasma glucose and insulin responses were suppressed by inhibition of PVN neuronal activity only during the dark period. These results indicate that the pre-autonomic neurons in the PVN are controlled by an interplay of inhibitory and excitatory inputs. Liver-dedicated sympathetic pre-autonomic neurons (responsible for hepatic glucose production) and pancreas-dedicated pre-autonomic parasympathetic neurons (responsible for insulin release) are controlled by inhibitory GABAergic contacts that are mainly active during the light period. Both sympathetic and parasympathetic pre-autonomic PVN neurons also receive excitatory inputs, either from the biological clock (sympathetic pre-autonomic neurons) or from non-clock areas (para-sympathetic pre-autonomic neurons), but the timing information is mainly provided by the GABAergic outputs of the biological clock.

Circadian Control of the Daily Plasma Glucose Rhythm: An Interplay of GABA and Glutamate

PubMed Central

Kalsbeek, Andries; Foppen, Ewout; Schalij, Ingrid; Van Heijningen, Caroline; van der Vliet, Jan; Fliers, Eric; Buijs, Ruud M.

2008-01-01

The mammalian biological clock, located in the hypothalamic suprachiasmatic nuclei (SCN), imposes its temporal structure on the organism via neural and endocrine outputs. To further investigate SCN control of the autonomic nervous system we focused in the present study on the daily rhythm in plasma glucose concentrations. The hypothalamic paraventricular nucleus (PVN) is an important target area of biological clock output and harbors the pre-autonomic neurons that control peripheral sympathetic and parasympathetic activity. Using local administration of GABA and glutamate receptor (ant)agonists in the PVN at different times of the light/dark-cycle we investigated whether daily changes in the activity of autonomic nervous system contribute to the control of plasma glucose and plasma insulin concentrations. Activation of neuronal activity in the PVN of non-feeding animals, either by administering a glutamatergic agonist or a GABAergic antagonist, induced hyperglycemia. The effect of the GABA-antagonist was time dependent, causing increased plasma glucose concentrations only when administered during the light period. The absence of a hyperglycemic effect of the GABA-antagonist in SCN-ablated animals provided further evidence for a daily change in GABAergic input from the SCN to the PVN. On the other hand, feeding-induced plasma glucose and insulin responses were suppressed by inhibition of PVN neuronal activity only during the dark period. These results indicate that the pre-autonomic neurons in the PVN are controlled by an interplay of inhibitory and excitatory inputs. Liver-dedicated sympathetic pre-autonomic neurons (responsible for hepatic glucose production) and pancreas-dedicated pre-autonomic parasympathetic neurons (responsible for insulin release) are controlled by inhibitory GABAergic contacts that are mainly active during the light period. Both sympathetic and parasympathetic pre-autonomic PVN neurons also receive excitatory inputs, either from the biological clock (sympathetic pre-autonomic neurons) or from non-clock areas (para-sympathetic pre-autonomic neurons), but the timing information is mainly provided by the GABAergic outputs of the biological clock. PMID:18791643

A paradigm shift in pharmacokinetic-pharmacodynamic (PKPD) modeling: rule of thumb for estimating free drug level in tissue compared with plasma to guide drug design.

PubMed

Poulin, Patrick

2015-07-01

A basic assumption in pharmacokinetics-pharmacodynamics research is that the free drug concentration is similar in plasma and tissue, and, hence, in vitro plasma data can be used to estimate the in vivo condition in tissue. However, in a companion manuscript, it has been demonstrated that this assumption is violated for the ionized drugs. Nonetheless, these observations focus on in vitro static environments and do not challenge data with an in vivo dynamic system. Therefore, an extension from an in vitro to an in vivo system becomes the necessary next step. The objective of this study was to perform theoretical simulations of the free drug concentration in tissue and plasma by using a physiologically based pharmacokinetics (PBPK) model reproducing the in vivo conditions in human. Therefore, the effects of drug ionization, lipophilicity, and clearance have been taken into account in a dynamic system. This modeling exercise was performed as a proof of concept to demonstrate that free drug concentration in tissue and plasma may also differ in a dynamic system for passively permeable drugs that are ionized at the physiological pH. The PBPK model simulations indicated that free drug concentrations in tissue cells and plasma significantly differ for the ionized drugs because of the pH gradient effect between cells and interstitial space. Hence, a rule of thumb for potentially performing more accurate PBPK/PD modeling is suggested, which states that the free drug concentration in tissue and plasma will differ for the ionizable drugs in contrast to the neutral drugs. In addition to the pH gradient effect for the ionizable drugs, lipophilicity and clearance effects will increase or decrease the free drug concentration in tissue and plasma for each class of drugs; thus, higher will be the drug lipophilicity and clearance, lower would be the free drug concentration in plasma, and, hence, in tissue, in a dynamic in vivo system. Therefore, only considering the value of free fraction in plasma derived from a static in vitro environment might be biased to guide drug design (the old paradigm), and, hence, it is recommended to use a PBPK model to reproduce more accurately the in vivo condition in tissue (the new paradigm). This newly developed approach can be used to predict free drug concentration in diverse tissue compartments for small molecules in toxicology and pharmacology studies, which can be leveraged to optimize the pharmacokinetics drivers of tissue distribution based upon physicochemical and physiological input parameters in an attempt to optimize free drug level in tissue. Overall, this present study provides guidance on the application of plasma and tissue concentration information in PBPK/PD research in preclinical and clinical studies, which is in accordance with the recent literature. © 2015 Wiley Periodicals, Inc. and the American Pharmacists Association.

Status of Hollow Cathode Heater Development for the Space Station Plasma Contactor

NASA Technical Reports Server (NTRS)

Soulas, George C.

1994-01-01

A hollow cathode-based plasma contactor has been selected for use on the Space Station. During the operation of the plasma contactor, the hollow cathode heater will endure approximately 12000 thermal cycles. Since a hollow cathode heater failure would result in a plasma contactor failure, a hollow cathode heater development program was established to produce a reliable heater. The development program includes the heater design, process documents for both heater fabrication and assembly, and heater testing. The heater design was a modification of a sheathed ion thruster cathode heater. Heater tests included testing of the heater unit alone and plasma contactor and ion thruster testing. To date, eight heaters have been or are being processed through heater unit testing, two through plasma contactor testing and three through ion thruster testing, all using direct current power supplies. Comparisons of data from heater unit performance tests before cyclic testing, plasma contactor tests, and ion thruster tests at the ignition input current level show the average deviation of input power and tube temperature near the cathode tip to be +/-0.9 W and +/- 21 C, respectively. Heater unit testing included cyclic testing to evaluate reliability under thermal cycling. The first heater, although damaged during assembly, completed 5985 ignition cycles before failing. Four additional heaters successfully completed 6300, 6300, 700, and 700 cycles. Heater unit testing is currently ongoing for three heaters which have to date accumulated greater than 7250, greater than 5500, and greater than 5500 cycles, respectively.

Enhanced stimulated Raman scattering by femtosecond ultraviolet plasma grating in water

NASA Astrophysics Data System (ADS)

Liu, Fengjiang; Yuan, Shuai; He, Boqu; Nan, Junyi; Khan, Abdul Qayyum; Ding, Liang'en; Zeng, Heping

2018-02-01

Efficient forward stimulated Raman scattering (SRS) was observed along 400-nm femtosecond (fs) laser filaments in water. SRS conversion dominated over self-phase modulation induced continuum generation as the input pulse energy was above 4 μJ (˜30 Pcr), implying that plasma in the aqueous filamentation channel played an important role in compensating for the group velocity walk-off between the pump and Stokes pulses. By overlapping two synchronous fs 400-nm filaments to form plasma grating in water, significant enhancement of SRS conversion was observed. Such a SRS enhancement originated from the ultrahigh plasma density in the intersection region of the preformed plasma grating.

Particle based plasma simulation for an ion engine discharge chamber

NASA Astrophysics Data System (ADS)

Mahalingam, Sudhakar

Design of the next generation of ion engines can benefit from detailed computer simulations of the plasma in the discharge chamber. In this work a complete particle based approach has been taken to model the discharge chamber plasma. This is the first time that simplifying continuum assumptions on the particle motion have not been made in a discharge chamber model. Because of the long mean free paths of the particles in the discharge chamber continuum models are questionable. The PIC-MCC model developed in this work tracks following particles: neutrals, singly charged ions, doubly charged ions, secondary electrons, and primary electrons. The trajectories of these particles are determined using the Newton-Lorentz's equation of motion including the effects of magnetic and electric fields. Particle collisions are determined using an MCC statistical technique. A large number of collision processes and particle wall interactions are included in the model. The magnetic fields produced by the permanent magnets are determined using Maxwell's equations. The electric fields are determined using an approximate input electric field coupled with a dynamic determination of the electric fields caused by the charged particles. In this work inclusion of the dynamic electric field calculation is made possible by using an inflated plasma permittivity value in the Poisson solver. This allows dynamic electric field calculation with minimal computational requirements in terms of both computer memory and run time. In addition, a number of other numerical procedures such as parallel processing have been implemented to shorten the computational time. The primary results are those modeling the discharge chamber of NASA's NSTAR ion engine at its full operating power. Convergence of numerical results such as total number of particles inside the discharge chamber, average energy of the plasma particles, discharge current, beam current and beam efficiency are obtained. Steady state results for the particle number density distributions and particle loss rates to the walls are presented. Comparisons of numerical results with experimental measurements such as currents and the particle number density distributions are made. Results from a parametric study and from an alternative magnetic field design are also given.

ERO modeling and sensitivity analysis of locally enhanced beryllium erosion by magnetically connected antennas

NASA Astrophysics Data System (ADS)

Lasa, A.; Borodin, D.; Canik, J. M.; Klepper, C. C.; Groth, M.; Kirschner, A.; Airila, M. I.; Borodkina, I.; Ding, R.; Contributors, JET

2018-01-01

Experiments at JET showed locally enhanced, asymmetric beryllium (Be) erosion at outer wall limiters when magnetically connected ICRH antennas were in operation. A first modeling effort using the 3D erosion and scrape-off layer impurity transport modeling code ERO reproduced qualitatively the experimental outcome. However, local plasma parameters—in particular when 3D distributions are of interest—can be difficult to determine from available diagnostics and so erosion / impurity transport modeling input relies on output from other codes and simplified models, increasing uncertainties in the outcome. In the present contribution, we introduce and evaluate the impact of improved models and parameters with largest uncertainties of processes that impact impurity production and transport across the scrape-off layer, when simulated in ERO: (i) the magnetic geometry has been revised, for affecting the separatrix position (located 50-60 mm away from limiter surface) and thus the background plasma profiles; (ii) connection lengths between components, which lead to shadowing of ion fluxes, are also affected by the magnetic configuration; (iii) anomalous transport of ionized impurities, defined by the perpendicular diffusion coefficient, has been revisited; (iv) erosion yields that account for energy and angular distributions of background plasma ions under the present enhanced sheath potential and oblique magnetic field, have been introduced; (v) the effect of additional erosion sources, such as charge-exchange neutral fluxes, which are dominant in recessed areas like antennas, has been evaluated; (vi) chemically assisted release of Be in molecular form has been included. Sensitivity analysis highlights a qualitative effect (i.e. change in emission patterns) of magnetic shadowing, anomalous diffusion, and inclusion of neutral fluxes and molecular release of Be. The separatrix location, and energy and angular distribution of background plasma fluxes impact erosion quantitatively. ERO simulations that include all features described above match experimentally measured Be I (457.3 nm) and Be II (467.4 nm) signals, and erosion increases with varying ICRH antenna’s RF power. However, this increase in erosion is only partially captured by ERO’s emission measurements, as most contributions from plasma wetted surfaces fall outside the volume observed by sightlines. ).

Simplifying [18F]GE-179 PET: are both arterial blood sampling and 90-min acquisitions essential?

PubMed

McGinnity, Colm J; Riaño Barros, Daniela A; Trigg, William; Brooks, David J; Hinz, Rainer; Duncan, John S; Koepp, Matthias J; Hammers, Alexander

2018-06-11

The NMDA receptor radiotracer [ 18 F]GE-179 has been used with 90-min scans and arterial plasma input functions. We explored whether (1) arterial blood sampling is avoidable and (2) shorter scans are feasible. For 20 existing [ 18 F]GE-179 datasets, we generated (1) standardised uptake values (SUVs) over eight intervals; (2) volume of distribution (V T ) images using population-based input functions (PBIFs), scaled using one parent plasma sample; and (3) V T images using three shortened datasets, using the original parent plasma input functions (ppIFs). Correlations with the original ppIF-derived 90-min V T s increased for later interval SUVs (maximal ρ = 0.78; 80-90 min). They were strong for PBIF-derived V T s (ρ = 0.90), but between-subject coefficient of variation increased. Correlations were very strong for the 60/70/80-min original ppIF-derived V T s (ρ = 0.97-1.00), which suffered regionally variant negative bias. Where arterial blood sampling is available, reduction of scan duration to 60 min is feasible, but with negative bias. The performance of SUVs was more consistent across participants than PBIF-derived V T s.

The autonomic nervous system regulates postprandial hepatic lipid metabolism.

PubMed

Bruinstroop, Eveline; la Fleur, Susanne E; Ackermans, Mariette T; Foppen, Ewout; Wortel, Joke; Kooijman, Sander; Berbée, Jimmy F P; Rensen, Patrick C N; Fliers, Eric; Kalsbeek, Andries

2013-05-15

The liver is a key organ in controlling glucose and lipid metabolism during feeding and fasting. In addition to hormones and nutrients, inputs from the autonomic nervous system are also involved in fine-tuning hepatic metabolic regulation. Previously, we have shown in rats that during fasting an intact sympathetic innervation of the liver is essential to maintain the secretion of triglycerides by the liver. In the current study, we hypothesized that in the postprandial condition the parasympathetic input to the liver inhibits hepatic VLDL-TG secretion. To test our hypothesis, we determined the effect of selective surgical hepatic denervations on triglyceride metabolism after a meal in male Wistar rats. We report that postprandial plasma triglyceride concentrations were significantly elevated in parasympathetically denervated rats compared with control rats (P = 0.008), and VLDL-TG production tended to be increased (P = 0.066). Sympathetically denervated rats also showed a small rise in postprandial triglyceride concentrations (P = 0.045). On the other hand, in rats fed on a six-meals-a-day schedule for several weeks, a parasympathetic denervation resulted in >70% higher plasma triglycerides during the day (P = 0.001), whereas a sympathetic denervation had no effect. Our results show that abolishing the parasympathetic input to the liver results in increased plasma triglyceride levels during postprandial conditions.

Investigation of the transport shortfall in Alcator C-Mod L-mode plasmas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Howard, N. T.; White, A. E.; Greenwald, M.

2013-03-15

A so-called 'transport shortfall,' where ion and electron heat fluxes and turbulence are underpredicted by gyrokinetic codes, has been robustly identified in DIII-D L-mode plasmas for {rho}>0.55[T. L. Rhodes et al., Nucl. Fusion 51(6), 063022 (2011); and C. Holland et al., Phys. Plasmas 16(5), 052301 (2009)]. To probe the existence of a transport shortfall across different tokamaks, a dedicated scan of auxiliary heated L-mode discharges in Alcator C-Mod are studied in detail with nonlinear gyrokinetic simulations for the first time. Two discharges, only differing by the amount of auxiliary heating are investigated using both linear and nonlinear simulation of themore » GYRO code [J. Candy and R. E. Waltz, J. Comput. Phys. 186, 545 (2003)]. Nonlinear gyrokinetic simulation of the low and high input power discharges reveals a discrepancy between simulation and experiment in only the electron heat flux channel of the low input power discharge. However, both discharges demonstrate excellent agreement in the ion heat flux channel, and the high input power discharge demonstrates simultaneous agreement with experiment in both the electron and ion heat flux channels. A summary of linear and nonlinear gyrokinetic results and a discussion of possible explanations for the agreement/disagreement in each heat flux channel is presented.« less

Calculation of Eddy Currents In the CTH Vacuum Vessel and Coil Frame

DOE Office of Scientific and Technical Information (OSTI.GOV)

A. Zolfaghari, A. Brooks, A. Michaels, J. Hanson, and G. Hartwell

2012-09-25

Knowledge of eddy currents in the vacuum vessel walls and nearby conducting support structures can significantly contribute to the accuracy of Magnetohydrodynamics (MHD) equilibrium reconstruction in toroidal plasmas. Moreover, the magnetic fields produced by the eddy currents could generate error fields that may give rise to islands at rational surfaces or cause field lines to become chaotic. In the Compact Toroidal Hybrid (CTH) device (R0 = 0.75 m, a = 0.29 m, B ≤ 0.7 T), the primary driver of the eddy currents during the plasma discharge is the changing flux of the ohmic heating transformer. Electromagnetic simulations are usedmore » to calculate eddy current paths and profile in the vacuum vessel and in the coil frame pieces with known time dependent currents in the ohmic heating coils. MAXWELL and SPARK codes were used for the Electromagnetic modeling and simulation. MAXWELL code was used for detailed 3D finite-element analysis of the eddy currents in the structures. SPARK code was used to calculate the eddy currents in the structures as modeled with shell/surface elements, with each element representing a current loop. In both cases current filaments representing the eddy currents were prepared for input into VMEC code for MHD equilibrium reconstruction of the plasma discharge. __________________________________________________« less

Probability Density Functions of the Solar Wind Driver of the Magnetopshere-Ionosphere System

NASA Astrophysics Data System (ADS)

Horton, W.; Mays, M. L.

2007-12-01

The solar-wind driven magnetosphere-ionosphere system is a complex dynamical system in that it exhibits (1) sensitivity to initial conditions; (2) multiple space-time scales; (3) bifurcation sequences with hysteresis in transitions between attractors; and (4) noncompositionality. This system is modeled by WINDMI--a network of eight coupled ordinary differential equations which describe the transfer of power from the solar wind through the geomagnetic tail, the ionosphere, and ring current in the system. The model captures both storm activity from the plasma ring current energy, which yields a model Dst index result, and substorm activity from the region 1 field aligned current, yielding model AL and AU results. The input to the model is the solar wind driving voltage calculated from ACE solar wind parameter data, which has a regular coherent component and broad-band turbulent component. Cross correlation functions of the input-output data time series are computed and the conditional probability density function for the occurrence of substorms given earlier IMF conditions are derived. The model shows a high probability of substorms for solar activity that contains a coherent, rotating IMF with magnetic cloud features. For a theoretical model of the imprint of solar convection on the solar wind we have used the Lorenz attractor (Horton et al., PoP, 1999, doi:10.10631.873683) as a solar wind driver. The work is supported by NSF grant ATM-0638480.

Characterization of a spray torch and analysis of process parameters

NASA Astrophysics Data System (ADS)

Ramasamy, R.; Selvarajan, V.

1999-07-01

Anode for a non-transferred DC plasma spray torch was designed to improve electrothermal efficiency. A theoretical calculation was made for the electrothermal efficiency in a DC plasma torch operating with argon at atmospheric pressure with power level in the range of 5.2 20 kW using energy balance equations. ANOVA for the two level factorial design was done. Plasma gas flow rate, current intensity, nozzle diameter and length were found to influence the efficiency. The efficiency was found to decrease with increase in current intensity and nozzle length and to increase with increase in nozzle diameter and gas flow rate. The overall energy balance calculations showed that the heat transfer to the plasma-forming gas decreases with increase in arc current and the same was more significant at higher flow rates. Plasma jet velocity for different flow rates, input to the torch and nozzle dimensions was calculated from the gas enthalpy. It was found that the velocity increased with increase in the power input to the torch and gas flow rate and decreased with increase in nozzle length and diameter. The current voltage characteristics of the torch operating with argon gas were studied for different gas flow rates. The Nottingham coefficients were calculated using least square method.

Characterizing the Meso-scale Plasma Flows in Earth's Coupled Magnetosphere-Ionosphere-Thermosphere System

NASA Astrophysics Data System (ADS)

Gabrielse, C.; Nishimura, T.; Lyons, L. R.; Gallardo-Lacourt, B.; Deng, Y.; McWilliams, K. A.; Ruohoniemi, J. M.

2017-12-01

NASA's Heliophysics Decadal Survey put forth several imperative, Key Science Goals. The second goal communicates the urgent need to "Determine the dynamics and coupling of Earth's magnetosphere, ionosphere, and atmosphere and their response to solar and terrestrial inputs...over a range of spatial and temporal scales." Sun-Earth connections (called Space Weather) have strong societal impacts because extreme events can disturb radio communications and satellite operations. The field's current modeling capabilities of such Space Weather phenomena include large-scale, global responses of the Earth's upper atmosphere to various inputs from the Sun, but the meso-scale ( 50-500 km) structures that are much more dynamic and powerful in the coupled system remain uncharacterized. Their influences are thus far poorly understood. We aim to quantify such structures, particularly auroral flows and streamers, in order to create an empirical model of their size, location, speed, and orientation based on activity level (AL index), season, solar cycle (F10.7), interplanetary magnetic field (IMF) inputs, etc. We present a statistical study of meso-scale flow channels in the nightside auroral oval and polar cap using SuperDARN. These results are used to inform global models such as the Global Ionosphere Thermosphere Model (GITM) in order to evaluate the role of meso-scale disturbances on the fully coupled magnetosphere-ionosphere-thermosphere system. Measuring the ionospheric footpoint of magnetospheric fast flows, our analysis technique from the ground also provides a 2D picture of flows and their characteristics during different activity levels that spacecraft alone cannot.

Studying the Relationship between High-Latitude Geomagnetic Activity and Parameters of Interplanetary Magnetic Clouds with the Use of Artificial Neural Networks

NASA Astrophysics Data System (ADS)

Barkhatov, N. A.; Revunov, S. E.; Vorobjev, V. G.; Yagodkina, O. I.

2018-03-01

The cause-and-effect relations of the dynamics of high-latitude geomagnetic activity (in terms of the AL index) and the type of the magnetic cloud of the solar wind are studied with the use of artificial neural networks. A recurrent neural network model has been created based on the search for the optimal physically coupled input and output parameters characterizing the action of a plasma flux belonging to a certain magnetic cloud type on the magnetosphere. It has been shown that, with IMF components as input parameters of neural networks with allowance for a 90-min prehistory, it is possible to retrieve the AL sequence with an accuracy to 80%. The successful retrieval of the AL dynamics by the used data indicates the presence of a close nonlinear connection of the AL index with cloud parameters. The created neural network models can be applied with high efficiency to retrieve the AL index, both in periods of isolated magnetospheric substorms and in periods of the interaction between the Earth's magnetosphere and magnetic clouds of different types. The developed model of AL index retrieval can be used to detect magnetic clouds.

Experimental observation of self excited co-rotating multiple vortices in a dusty plasma with inhomogeneous plasma background

NASA Astrophysics Data System (ADS)

Choudhary, Mangilal; Mukherjee, S.; Bandyopadhyay, P.

2017-03-01

We report an experimental observation of multiple co-rotating vortices in an extended dust column in the background of an inhomogeneous diffused plasma. An inductively coupled rf discharge is initiated in the background of argon gas in the source region. This plasma was later found to diffuse into the main experimental chamber. A secondary DC glow discharge plasma is produced to introduce dust particles into the plasma volume. These micron-sized poly-disperse dust particles get charged in the background of the DC plasma and are transported by the ambipolar electric field of the diffused plasma. These transported particles are found to be confined in an electrostatic potential well, where the resultant electric field due to the diffused plasma (ambipolar E-field) and glass wall charging (sheath E-field) holds the micron-sized particles against the gravity. Multiple co-rotating (anti-clockwise) dust vortices are observed in the dust cloud for a particular discharge condition. The transition from multiple vortices to a single dust vortex is observed when input rf power is lowered. The occurrence of these vortices is explained on the basis of the charge gradient of dust particles, which is orthogonal to the ion drag force. The charge gradient is a consequence of the plasma inhomogeneity along the dust cloud length. The detailed nature and the reason for multiple vortices are still under investigation through further experiments; however, preliminary qualitative understanding is discussed based on the characteristic scale length of the dust vortex. There is a characteristic size of the vortex in the dusty plasma; therefore, multiple vortices could possibly be formed in an extended dusty plasma with inhomogeneous plasma background. The experimental results on the vortex motion of particles are compared with a theoretical model and are found to be in close agreement.

Advancing Non-Solenoidal Startup on the Pegasus ST

NASA Astrophysics Data System (ADS)

Reusch, J. A.; Barr, J. L.; Bodner, G. M.; Bongard, M. W.; Burke, M. G.; Fonck, R. J.; Pachicano, J. L.; Perry, J. M.; Richner, N. J.; Rodriguez Sanchez, C.; Schlossberg, D. J.

2016-10-01

The Pegasus experiment utilizes compact, edge-localized current sources (Ainj 2 - 4 cm2, Iinj 10 kA, Vinj 1 kV) for non-solenoidal local helicity injection (LHI) startup. Recent campaigns are comparing two injector geometries that vary the differing relative contributions of DC helicity input and non-solenoidal inductive voltages. A predictive 0-D model that treats the plasma as a resistive element with time-varying inductance and enforces Ip limits from Taylor relaxation was tested with inward growth of the plasma current channel using injectors on the outboard midplane. Strong inductive drive arises from plasma shape evolution and poloidal field (PF) induction. A major unknown in the model is the resistive dissipation, and hence the electron confinement. Te (R) profile measurements in LHI show centrally-peaked Te > 100 eV while the plasma is coupled to the injectors, suggesting LHI confinement is not strongly stochastic. A second campaign utilizes new injectors in the lower divertor region. This geometry trades subtler relaxation field programming and reduced PF induction for higher HI rates. Present efforts are developing relaxation methods at high BT, with relaxation at BT , inj > 0.15 T achieved to date via higher Iinj and PF manipulation. Conceptual design studies of coaxial helicity injection (CHI) and ECH heating systems for Pegasus have been initiated to explore direct comparison of LHI to CHI with and without ECH assist. Supported by US DOE Grants DE-FG02-96ER54375, DE-SC0006928.

Dielectric barrier discharge-based plasma actuator operation in artificial atmospheres for validation of modeling and simulation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mangina, R. S.; Enloe, C. L.; Font, G. I.

2015-11-15

We present an experimental case study of time-resolved force production by an aerodynamic plasma actuator immersed in various mixtures of electropositive (N{sub 2}) and electronegative gases (O{sub 2} and SF{sub 6}) at atmospheric pressure using a fixed AC high-voltage input of 16 kV peak amplitude at 200 Hz frequency. We have observed distinct changes in the discharge structures during both negative- and positive-going voltage half-cycles, with corresponding variations in the actuator's force production: a ratio of 4:1 in the impulse produced by the negative-going half-cycle of the discharge among the various gas mixtures we explored, 2:1 in the impulse produced by themore » positive-going half-cycle, and cases in which the negative-going half-cycle dominates force production (by a ratio of 1.5:1), where the half-cycles produce identical force levels, and where the positive-going half cycle dominates (by a ratio of 1:5). We also present time-resolved experimental evidence for the first time that shows electrons do play a significant role in the momentum coupling to surrounding neutrals during the negative going voltage half-cycle of the N{sub 2} discharge. We show that there is sufficient macroscopic variation in the plasma that the predictions of numerical models at the microscopic level can be validated even though the plasma itself cannot be measured directly on those spatial and temporal scales.« less

Boundary condition for toroidal plasma flow imposed at the separatrix in high confinement JT-60U plasmas with edge localized modes and the physics process in pedestal structure formation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kamiya, K.; Honda, M.; Urano, H.

2014-12-15

Modulation charge eXchange recombination spectroscopy measurements with high spatial and temporal resolution have made the evaluation of the toroidal plasma flow of fully stripped carbon impurity ions (V{sub ϕ}{sup C6+}) in the JT-60U tokamak peripheral region (including, in particular, the separatrix) possible with a better signal-to-noise ratio. By comparing co- and counter-neutral beam injection discharges experimentally, we have identified the boundary condition of V{sub ϕ}{sup C6+} and radial electric field shear (∇E{sub r}) imposed at the separatrix in high confinement (H-mode) plasmas with edge localized modes (ELMs). The V{sub ϕ}{sup C6+} value at the separatrix is not fixed at zeromore » but varies with the momentum input direction. On the other hand, the ∇E{sub r} value is nearly zero (or very weakly positive) at the separatrix. Furthermore, the edge localized mode perturbation does not appear to affect both V{sub ϕ}{sup C6+} and ∇E{sub r} values at the separatrix as strongly as that in the pedestal region. The above experimental findings based on the precise edge measurements have been used to validate a theoretical model and develop a new empirical model. A better understanding of the physical process in the edge transport barrier (ETB) formation due to the sheared E{sub r} formation is also discussed.« less

Central Safety Factor and Normalized Beta Control Under Near-Zero Input Torque Constraints in DIII-D

NASA Astrophysics Data System (ADS)

Pajares, Andres; Wehner, William; Schuster, Eugenio; Burrell, Keith; Ferron, John; Walker, Michael; Humphreys, David; Lehigh University Team; Atomics Team, General

2017-10-01

DIII-D experiments have assessed the capability of combined central safety factor (q0) and normalized beta (βN) control under near-zero net torque to facilitate access to QH-mode with reverse Ip and normal Bt. Regulation of q0 and βN can prevent magneto-hydrodynamic instabilities that deteriorate plasma performance in discharges with a monotonically increasing safety-factor profile. Zero-input-torque scenarios are of special interest because future burning plasma tokamaks such as ITER will most likely operate with very low input torque, which makes these scenarios more susceptible to locked modes. To support studies of such scenarios, a controller for simultaneous regulation of q0 and βN has been developed using near-zero net input torque actuators including balanced neutral beam injection (NBI) and electron-cyclotron heating & current drive (ECH/ECCD). Experimental results show that in spite of the presence of locked modes the use of feedback control resulted in good tracking of the commanded q0 and βN when both ECCD/ECH and NBI were available. Supported by the US DOE under DE-SC0010661 and DE-FC02-04ER54698.

Using the Flipchem Photochemistry Model When Fitting Incoherent Scatter Radar Data

NASA Astrophysics Data System (ADS)

Reimer, A. S.; Varney, R. H.

2017-12-01

The North face Resolute Bay Incoherent Scatter Radar (RISR-N) routinely images the dynamics of the polar ionosphere, providing measurements of the plasma density, electron temperature, ion temperature, and line of sight velocity with seconds to minutes time resolution. RISR-N does not directly measure ionospheric parameters, but backscattered signals, recording them as voltage samples. Using signal processing techniques, radar autocorrelation functions (ACF) are estimated from the voltage samples. A model of the signal ACF is then fitted to the ACF using non-linear least-squares techniques to obtain the best-fit ionospheric parameters. The signal model, and therefore the fitted parameters, depend on the ionospheric ion composition that is used [e.g. Zettergren et. al. (2010), Zou et. al. (2017)].The software used to process RISR-N ACF data includes the "flipchem" model, which is an ion photochemistry model developed by Richards [2011] that was adapted from the Field LineInterhemispheric Plasma (FLIP) model. Flipchem requires neutral densities, neutral temperatures, electron density, ion temperature, electron temperature, solar zenith angle, and F10.7 as inputs to compute ion densities, which are input to the signal model. A description of how the flipchem model is used in RISR-N fitting software will be presented. Additionally, a statistical comparison of the fitted electron density, ion temperature, electron temperature, and velocity obtained using a flipchem ionosphere, a pure O+ ionosphere, and a Chapman O+ ionosphere will be presented. The comparison covers nearly two years of RISR-N data (April 2015 - December 2016). Richards, P. G. (2011), Reexamination of ionospheric photochemistry, J. Geophys. Res., 116, A08307, doi:10.1029/2011JA016613.Zettergren, M., Semeter, J., Burnett, B., Oliver, W., Heinselman, C., Blelly, P.-L., and Diaz, M.: Dynamic variability in F-region ionospheric composition at auroral arc boundaries, Ann. Geophys., 28, 651-664, https://doi.org/10.5194/angeo-28-651-2010, 2010.Zou, S., D. Ozturk, R. Varney, and A. Reimer (2017), Effects of sudden commencement on the ionosphere: PFISR observations and global MHD simulation, Geophys. Res. Lett., 44, 3047-3058, doi:10.1002/2017GL072678.

Estimation of Electron Temperature on Glass Spherical Tokamak (GLAST)

NASA Astrophysics Data System (ADS)

Hussain, S.; Sadiq, M.; Shah, S. I. W.; GLAST Team

2015-03-01

Glass Spherical Tokamak (GLAST) is a small spherical tokamak indigenously developed in Pakistan with an insulating vacuum vessel. A commercially available 2.45 GHz magnetron is used as pre-ionization source for plasma current startup. Different diagnostic systems like Rogowski coils, magnetic probes, flux loops, Langmuir probe, fast imaging and emission spectroscopy are installed on the device. The plasma temperature inside of GLAST, at the time of maxima of plasma current, is estimated by taking into account the Spitzer resistivity calculations with some experimentally determined plasma parameters. The plasma resistance is calculated by using Ohm's law with plasma current and loop voltage as experimentally determined inputs. The plasma resistivity is then determined by using length and area of the plasma column. Finally, the average plasma electron temperature is predicted to be 12.65eV for taking neon (Ne) as a working gas.

Uranium plasma emission at gas-core reaction conditions

NASA Technical Reports Server (NTRS)

Williams, M. D.; Jalufka, N. W.; Hohl, F.; Lee, J. H.

1976-01-01

The results of uranium plasma emission produced by two methods are reported. For the first method a ruby laser was focused on the surface of a pure U-238 sample to create a plasma plume with a peak plasma density of about 10 to the 20th power/cu cm and a temperature of about 38,600 K. The absolute intensity of the emitted radiation, covering the range from 300 to 7000 A was measured. For the second method, the uranium plasma was produced in a 20 kilovolt, 25 kilojoule plasma-focus device. The 2.5 MeV neutrons from the D-D reaction in the plasma focus are moderated by polyethylene and induce fissions in the U-235. Spectra of both uranium plasmas were obtained over the range from 30 to 9000 A. Because of the low fission yield the energy input due to fissions is very small compared to the total energy in the plasma.

Effect of cathode cooling efficiency and oxygen plasma gas pressure on the hafnium cathode wall temperature

NASA Astrophysics Data System (ADS)

Ashtekar, Koustubh; Diehl, Gregory; Hamer, John

2012-10-01

The hafnium cathode is widely used in DC plasma arc cutting (PAC) under an oxygen gas environment to cut iron and iron alloys. The hafnium erosion is always a concern which is controlled by the surface temperature. In this study, the effect of cathode cooling efficiency and oxygen gas pressure on the hafnium surface temperature are quantified. The two layer cathode sheath model is applied on the refractive hafnium surface while oxygen species (O2, O, O+, O++, e-) are considered within the thermal dis-equilibrium regime. The system of non-linear equations comprising of current density balance, heat flux balance at both the cathode surface and the sheath-ionization layer is coupled with the plasma gas composition solver. Using cooling heat flux, gas pressure and current density as inputs; the cathode wall temperature, electron temperature, and sheath voltage drop are calculated. Additionally, contribution of emitted electron current (Je) and ions current (Ji) to the total current flux are estimated. Higher gas pressure usually reduces Ji and increases Je that reduces the surface temperature by thermionic cooling.

Electric dipole radiation at VLF in a uniform warm magneto-plasma.

NASA Technical Reports Server (NTRS)

Wang, T. N. C.; Bell, T. F.

1972-01-01

Use of a linear full electromagnetic wave theory to calculate the input impedance of an electric antenna embedded in a uniform, lossless, unbounded warm magnetoplasma, which is assumed to consist of warm electrons and cold ions. In calculating the dipole radiation resistance for the thermal modes and the thermally modified whistler mode the analysis includes the finite temperature only for the electrons. In deriving the formal solution of the warm plasma dipole input impedance a full-wave analysis is used and two antenna orientations are considered, parallel and perpendicular to the static magnetic field. A general dispersion equation governing the modes of propagation is derived and a detailed analysis is made of the propagation characteristics of these modes.

Mass- and energy-analyses of ions from plasma by means of a miniature Thomson spectrometer.

PubMed

Sadowski, M J; Czaus, K; Malinowski, K; Skladnik-Sadowska, E; Zebrowski, J

2009-05-01

The paper presents an improved version of a miniature mass-spectrometer of the Thomson-type, which has been adopted for ion analysis near the dense plasma region inside a vacuum chamber. Problems connected with the separation of ions from plasma streams are considered. Input diaphragms and pumping systems, needed to ensure good vacuum inside the analyzing region, are described. The application of the miniature Thomson-type analyzer is illustrated by ion parabolas recorded in plasma-focus facility and rod plasma injector experiment. A quantitative analysis of the recorded ion parabolas is presented. Factors influencing accuracy of the ion analysis are discussed and methods of the spectrometer calibration are described.

Synergistic effects of plasma-catalyst interactions for CH4 activation.

PubMed

Kim, Jongsik; Go, David B; Hicks, Jason C

2017-05-24

The elucidation of catalyst surface-plasma interactions is a challenging endeavor and therefore requires thorough and rigorous assessment of the reaction dynamics on the catalyst in the plasma environment. The first step in quantifying and defining catalyst-plasma interactions is a detailed kinetic study that can be used to verify appropriate reaction conditions for comparison and to discover any unexpected behavior of plasma-assisted reactions that might prevent direct comparison. In this paper, we provide a kinetic evaluation of CH 4 activation in a dielectric barrier discharge plasma in order to quantify plasma-catalyst interactions via kinetic parameters. The dry reforming of CH 4 with CO 2 was studied as a model reaction using Ni supported on γ-Al 2 O 3 at temperatures of 790-890 K under atmospheric pressure, where the partial pressures of CH 4 (or CO 2 ) were varied over a range of ≤25.3 kPa. Reaction performance was monitored by varying gas hourly space velocity, plasma power, bulk gas temperature, and reactant concentration. After correcting for gas-phase plasma reactions, a linear relationship was observed in the log of the measured rate constant with respect to reciprocal power (1/power). Although thermal catalysis displays typical Arrhenius behavior for this reaction, plasma-assisted catalysis occurs from a complex mixture of sources and shows non-Arrhenius behavior. However, an energy barrier was obtained from the relationship between the reaction rate constant and input power to exhibit ≤∼20 kJ mol -1 (compared to ∼70 kJ mol -1 for thermal catalysis). Of additional importance, the energy barriers measured during plasma-assisted catalysis were relatively consistent with respect to variations in total flow rates, types of diluent, or bulk reaction temperature. These experimental results suggest that plasma-generated vibrationally-excited CH 4 favorably interacts with Ni sites at elevated temperatures, which helps reduce the energy barrier required to activate CH 4 and enhance CH 4 reforming rates.

Submillimeter Spectroscopic Study of Semiconductor Processing Plasmas

NASA Astrophysics Data System (ADS)

Helal, Yaser H.

Plasmas used for manufacturing processes of semiconductor devices are complex and challenging to characterize. The development and improvement of plasma processes and models rely on feedback from experimental measurements. Current diagnostic methods are not capable of measuring absolute densities of plasma species with high resolution without altering the plasma, or without input from other measurements. At pressures below 100 mTorr, spectroscopic measurements of rotational transitions in the submillimeter/terahertz (SMM) spectral region are narrow enough in relation to the sparsity of spectral lines that absolute specificity of measurement is possible. The frequency resolution of SMM sources is such that spectral absorption features can be fully resolved. Processing plasmas are a similar pressure and temperature to the environment used to study astrophysical species in the SMM spectral region. Many of the molecular neutrals, radicals, and ions present in processing plasmas have been studied in the laboratory and their absorption spectra have been cataloged or are in the literature for the purpose of astrophysical study. Recent developments in SMM devices have made its technology commercially available for applications outside of specialized laboratories. The methods developed over several decades in the SMM spectral region for these laboratory studies are directly applicable for diagnostic measurements in the semiconductor manufacturing industry. In this work, a continuous wave, intensity calibrated SMM absorption spectrometer was developed as a remote sensor of gas and plasma species. A major advantage of intensity calibrated rotational absorption spectroscopy is its ability to determine absolute concentrations and temperatures of plasma species from first principles without altering the plasma environment. An important part of this work was the design of the optical components which couple 500 - 750 GHz radiation through a commercial inductively coupled plasma chamber. The measurement of transmission spectra was simultaneously fit for background and absorption signal. The measured absorption signal was used to calculate absolute densities and temperatures of polar species. Measurements of molecular species were demonstrated for inductively coupled plasmas.

The SMART Theory and Modeling Team: An Integrated Element of Mission Development and Science Analysis

NASA Technical Reports Server (NTRS)

Hesse, Michael; Birn, J.; Denton, Richard E.; Drake, J.; Gombosi, T.; Hoshino, M.; Matthaeus, B.; Sibeck, D.

2005-01-01

When targeting physical understanding of space plasmas, our focus is gradually shifting away from discovery-type investigations to missions and studies that address our basic understanding of processes we know to be important. For these studies, theory and models provide physical predictions that need to be verified or falsified by empirical evidence. Within this paradigm, a tight integration between theory, modeling, and space flight mission design and execution is essential. NASA's Magnetospheric MultiScale (MMS) mission is a pathfinder in this new era of space research. The prime objective of MMS is to understand magnetic reconnection, arguably the most fundamental of plasma processes. In particular, MMS targets the microphysical processes, which permit magnetic reconnection to operate in the collisionless plasmas that permeate space and astrophysical systems. More specifically, MMS will provide closure to such elemental questions as how particles become demagnetized in the reconnection diffusion region, which effects determine the reconnection rate, and how reconnection is coupled to environmental conditions such as magnetic shear angles. Solutions to these problems have remained elusive in past and present spacecraft missions primarily due to instrumental limitations - yet they are fundamental to the large-scale dynamics of collisionless plasmas. Owing to the lack of measurements, most of our present knowledge of these processes is based on results from modern theory and modeling studies of the reconnection process. Proper design and execution of a mission targeting magnetic reconnection should include this knowledge and have to ensure that all relevant scales and effects can be resolved by mission measurements. The SMART mission has responded to this need through a tight integration between instrument and theory and modeling teams. Input from theory and modeling is fed into all aspects of science mission design, and theory and modeling activities are tailored to SMART needs during mission development and science analysis. In this presentation, we will present an overview of SMART theory and modeling team activities. In particular, we will provide examples of science objectives derived from state-of-the art models, and of recent research results that continue to be utilized in SMART mission development.

Combining image-derived and venous input functions enables quantification of serotonin-1A receptors with [carbonyl-11C]WAY-100635 independent of arterial sampling.

PubMed

Hahn, Andreas; Nics, Lukas; Baldinger, Pia; Ungersböck, Johanna; Dolliner, Peter; Frey, Richard; Birkfellner, Wolfgang; Mitterhauser, Markus; Wadsak, Wolfgang; Karanikas, Georgios; Kasper, Siegfried; Lanzenberger, Rupert

2012-08-01

image- derived input functions (IDIFs) represent a promising technique for a simpler and less invasive quantification of PET studies as compared to arterial cannulation. However, a number of limitations complicate the routine use of IDIFs in clinical research protocols and the full substitution of manual arterial samples by venous ones has hardly been evaluated. This study aims for a direct validation of IDIFs and venous data for the quantification of serotonin-1A receptor binding (5-HT(1A)) with [carbonyl-(11)C]WAY-100635 before and after hormone treatment. Fifteen PET measurements with arterial and venous blood sampling were obtained from 10 healthy women, 8 scans before and 7 after eight weeks of hormone replacement therapy. Image-derived input functions were derived automatically from cerebral blood vessels, corrected for partial volume effects and combined with venous manual samples from 10 min onward (IDIF+VIF). Corrections for plasma/whole-blood ratio and metabolites were done separately with arterial and venous samples. 5-HT(1A) receptor quantification was achieved with arterial input functions (AIF) and IDIF+VIF using a two-tissue compartment model. Comparison between arterial and venous manual blood samples yielded excellent reproducibility. Variability (VAR) was less than 10% for whole-blood activity (p>0.4) and below 2% for plasma to whole-blood ratios (p>0.4). Variability was slightly higher for parent fractions (VARmax=24% at 5 min, p<0.05 and VAR<13% after 20 min, p>0.1) but still within previously reported values. IDIFs after partial volume correction had peak values comparable to AIFs (mean difference Δ=-7.6 ± 16.9 kBq/ml, p>0.1), whereas AIFs exhibited a delay (Δ=4 ± 6.4s, p<0.05) and higher peak width (Δ=15.9 ± 5.2s, p<0.001). Linear regression analysis showed strong agreement for 5-HT(1A) binding as obtained with AIF and IDIF+VIF at baseline (R(2)=0.95), after treatment (R(2)=0.93) and when pooling all scans (R(2)=0.93), with slopes and intercepts in the range of 0.97 to 1.07 and -0.05 to 0.16, respectively. In addition to the region of interest analysis, the approach yielded virtually identical results for voxel-wise quantification as compared to the AIF. Despite the fast metabolism of the radioligand, manual arterial blood samples can be substituted by venous ones for parent fractions and plasma to whole-blood ratios. Moreover, the combination of image-derived and venous input functions provides a reliable quantification of 5-HT(1A) receptors. This holds true for 5-HT(1A) binding estimates before and after treatment for both regions of interest-based and voxel-wise modeling. Taken together, the approach provides less invasive receptor quantification by full independence of arterial cannulation. This offers great potential for the routine use in clinical research protocols and encourages further investigation for other radioligands with different kinetic characteristics. Copyright © 2012 Elsevier Inc. All rights reserved.

The distribution of Enceladus water-group neutrals in Saturn’s Magnetosphere

NASA Astrophysics Data System (ADS)

Smith, Howard T.; Richardson, John D.

2017-10-01

Saturn’s magnetosphere is unique in that the plumes from the small icy moon, Enceladus, serve at the primary source for heavy particles in Saturn’s magnetosphere. The resulting co-orbiting neutral particles interact with ions, electrons, photons and other neutral particles to generate separate H2O, OH and O tori. Characterization of these toroidal distributions is essential for understanding Saturn magnetospheric sources, composition and dynamics. Unfortunately, limited direct observations of these features are available so modeling is required. A significant modeling challenge involves ensuring that either the plasma and neutral particle populations are not simply input conditions but can provide feedback to each population (i.e. are self-consistent). Jurac and Richardson (2005) executed such a self-consistent model however this research was performed prior to the return of Cassini data. In a similar fashion, we have coupled a 3-D neutral particle model (Smith et al. 2004, 2005, 2006, 2007, 2009, 2010) with a plasma transport model (Richardson 1998; Richardson & Jurac 2004) to develop a self-consistent model which is constrained by all available Cassini observations and current findings on Saturn’s magnetosphere and the Enceladus plume source resulting in much more accurate neutral particle distributions. Here a new self-consistent model of the distribution of the Enceladus-generated neutral tori that is validated by all available observations. We also discuss the implications for source rate and variability.

Analysis of non-equilibrium phenomena in inductively coupled plasma generators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, W.; Panesi, M., E-mail: mpanesi@illinois.edu; Lani, A.

This work addresses the modeling of non-equilibrium phenomena in inductively coupled plasma discharges. In the proposed computational model, the electromagnetic induction equation is solved together with the set of Navier-Stokes equations in order to compute the electromagnetic and flow fields, accounting for their mutual interaction. Semi-classical statistical thermodynamics is used to determine the plasma thermodynamic properties, while transport properties are obtained from kinetic principles, with the method of Chapman and Enskog. Particle ambipolar diffusive fluxes are found by solving the Stefan-Maxwell equations with a simple iterative method. Two physico-mathematical formulations are used to model the chemical reaction processes: (1) Amore » Local Thermodynamics Equilibrium (LTE) formulation and (2) a thermo-chemical non-equilibrium (TCNEQ) formulation. In the TCNEQ model, thermal non-equilibrium between the translational energy mode of the gas and the vibrational energy mode of individual molecules is accounted for. The electronic states of the chemical species are assumed in equilibrium with the vibrational temperature, whereas the rotational energy mode is assumed to be equilibrated with translation. Three different physical models are used to account for the coupling of chemistry and energy transfer processes. Numerical simulations obtained with the LTE and TCNEQ formulations are used to characterize the extent of non-equilibrium of the flow inside the Plasmatron facility at the von Karman Institute. Each model was tested using different kinetic mechanisms to assess the sensitivity of the results to variations in the reaction parameters. A comparison of temperatures and composition profiles at the outlet of the torch demonstrates that the flow is in non-equilibrium for operating conditions characterized by pressures below 30 000 Pa, frequency 0.37 MHz, input power 80 kW, and mass flow 8 g/s.« less

Analysis of non-equilibrium phenomena in inductively coupled plasma generators

NASA Astrophysics Data System (ADS)

Zhang, W.; Lani, A.; Panesi, M.

2016-07-01

This work addresses the modeling of non-equilibrium phenomena in inductively coupled plasma discharges. In the proposed computational model, the electromagnetic induction equation is solved together with the set of Navier-Stokes equations in order to compute the electromagnetic and flow fields, accounting for their mutual interaction. Semi-classical statistical thermodynamics is used to determine the plasma thermodynamic properties, while transport properties are obtained from kinetic principles, with the method of Chapman and Enskog. Particle ambipolar diffusive fluxes are found by solving the Stefan-Maxwell equations with a simple iterative method. Two physico-mathematical formulations are used to model the chemical reaction processes: (1) A Local Thermodynamics Equilibrium (LTE) formulation and (2) a thermo-chemical non-equilibrium (TCNEQ) formulation. In the TCNEQ model, thermal non-equilibrium between the translational energy mode of the gas and the vibrational energy mode of individual molecules is accounted for. The electronic states of the chemical species are assumed in equilibrium with the vibrational temperature, whereas the rotational energy mode is assumed to be equilibrated with translation. Three different physical models are used to account for the coupling of chemistry and energy transfer processes. Numerical simulations obtained with the LTE and TCNEQ formulations are used to characterize the extent of non-equilibrium of the flow inside the Plasmatron facility at the von Karman Institute. Each model was tested using different kinetic mechanisms to assess the sensitivity of the results to variations in the reaction parameters. A comparison of temperatures and composition profiles at the outlet of the torch demonstrates that the flow is in non-equilibrium for operating conditions characterized by pressures below 30 000 Pa, frequency 0.37 MHz, input power 80 kW, and mass flow 8 g/s.

Final Technical Report for SBIR entitled Four-Dimensional Finite-Orbit-Width Fokker-Planck Code with Sources, for Neoclassical/Anomalous Transport Simulation of Ion and Electron Distributions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harvey, R. W.; Petrov, Yu. V.

2013-12-03

Within the US Department of Energy/Office of Fusion Energy magnetic fusion research program, there is an important whole-plasma-modeling need for a radio-frequency/neutral-beam-injection (RF/NBI) transport-oriented finite-difference Fokker-Planck (FP) code with combined capabilities for 4D (2R2V) geometry near the fusion plasma periphery, and computationally less demanding 3D (1R2V) bounce-averaged capabilities for plasma in the core of fusion devices. Demonstration of proof-of-principle achievement of this goal has been carried out in research carried out under Phase I of the SBIR award. Two DOE-sponsored codes, the CQL3D bounce-average Fokker-Planck code in which CompX has specialized, and the COGENT 4D, plasma edge-oriented Fokker-Planck code whichmore » has been constructed by Lawrence Livermore National Laboratory and Lawrence Berkeley Laboratory scientists, where coupled. Coupling was achieved by using CQL3D calculated velocity distributions including an energetic tail resulting from NBI, as boundary conditions for the COGENT code over the two-dimensional velocity space on a spatial interface (flux) surface at a given radius near the plasma periphery. The finite-orbit-width fast ions from the CQL3D distributions penetrated into the peripheral plasma modeled by the COGENT code. This combined code demonstrates the feasibility of the proposed 3D/4D code. By combining these codes, the greatest computational efficiency is achieved subject to present modeling needs in toroidally symmetric magnetic fusion devices. The more efficient 3D code can be used in its regions of applicability, coupled to the more computationally demanding 4D code in higher collisionality edge plasma regions where that extended capability is necessary for accurate representation of the plasma. More efficient code leads to greater use and utility of the model. An ancillary aim of the project is to make the combined 3D/4D code user friendly. Achievement of full-coupling of these two Fokker-Planck codes will advance computational modeling of plasma devices important to the USDOE magnetic fusion energy program, in particular the DIII-D tokamak at General Atomics, San Diego, the NSTX spherical tokamak at Princeton, New Jersey, and the MST reversed-field-pinch Madison, Wisconsin. The validation studies of the code against the experiments will improve understanding of physics important for magnetic fusion, and will increase our design capabilities for achieving the goals of the International Tokamak Experimental Reactor (ITER) project in which the US is a participant and which seeks to demonstrate at least a factor of five in fusion power production divided by input power.« less

Scrape off layer modelling studies for SST-I

NASA Astrophysics Data System (ADS)

Warrier, M.; Jaishankar, S.; Deshpande, S.; Coster, D.; Schneider, R.; Chaturvedi, S.; Srinivasan, R.; Braams, B. J.; SST Team

SOL modelling results for SST-1 (SST Team, Proceedings of the 16th IEEE/NPSS Symposium on Fusion Engineering, Champaign, IL, vol. II, 1995, p. 481) show a sheath limited flow regime. This is due to the low edge densities required by lower hybrid current drive (LHCD), coupled with high power input per unit volume. Coupled plasma-neutral transport studies using B2-Eirene [R. Schneider et al., J. Nucl. Mater. 196-198 (1992) 810] show significantly high charge exchange losses and radiated power from the core. It also shows that the heat flux to the inner divertor is higher than that to the outer divertor due to thinner inner SOL widths. The Monte-Carlo neutral transport code DEGAS [D. Heifitz et al., J. Comput. Phys. 46 (1982) 309] was used to optimise the baffle plate geometry and it was seen that a configuration where the baffle plate shields the main plasma from the divertor strike point results in reduced backflow of neutrals. The divertor erosion code DIVER (M. Warrier et al., SST Divertor Modelling Report, 1996-1997) was used to predict a steady state operating temperature for the SST divertor plate lying in the range 750-1000°C for which the erosion will be minimum.

Nonlinear Burn Control and Operating Point Optimization in ITER

NASA Astrophysics Data System (ADS)

Boyer, Mark; Schuster, Eugenio

2013-10-01

Control of the fusion power through regulation of the plasma density and temperature will be essential for achieving and maintaining desired operating points in fusion reactors and burning plasma experiments like ITER. In this work, a volume averaged model for the evolution of the density of energy, deuterium and tritium fuel ions, alpha-particles, and impurity ions is used to synthesize a multi-input multi-output nonlinear feedback controller for stabilizing and modulating the burn condition. Adaptive control techniques are used to account for uncertainty in model parameters, including particle confinement times and recycling rates. The control approach makes use of the different possible methods for altering the fusion power, including adjusting the temperature through auxiliary heating, modulating the density and isotopic mix through fueling, and altering the impurity density through impurity injection. Furthermore, a model-based optimization scheme is proposed to drive the system as close as possible to desired fusion power and temperature references. Constraints are considered in the optimization scheme to ensure that, for example, density and beta limits are avoided, and that optimal operation is achieved even when actuators reach saturation. Supported by the NSF CAREER award program (ECCS-0645086).

Generation and Sustainment of Plasma Rotation by ICRF Heating

NASA Astrophysics Data System (ADS)

Perkins, F. W.

2000-10-01

When tokamak plasmas are heated by the fundamental minority ion-cyclotron process, they are observed to rotate toroidally, even though this heating process introduces negligable angular momentum. This work proposes and evaluates a physics mechanism which resolves this apparent conflict. The argument has two elements. First, it is assumed that angular momentum transport is governed by a diffusion equation with a v_tor = 0 boundary condition at the plasma surface and a torque-density source. When the source consists of separated regions of positive and negative torque density, a finite central rotation velocity results, even though the volume integrated torque density - the angular momentum input - vanishes. Secondly, ions energized by the ICRF process can generate separated regions of positive and negative torque density. Heating increases their banana widths which leads to radial energetic-particle transport that must be balanced by neutralizing radial currents and a j_rB_pR torque density in the bulk plasma. Additional, comparable torque density results from collisional transfer of mechanical angular momentum from energetic particles to the bulk plasma and particle loss through banana particles impacting the wall. Monte-Carlo calculations utilizing the ORBIT code evaluate all sources of torque density and rigorously assure that no net angular momentum is introduced. Two models of ICRF heating, diffusive and instantaneous, give similar results. When the resonance location is on the LFS, the calculated rotation has the magnitude, profile, and co-current sense of Alcator C-Mod observations. For HFS resonance locations, the model predicts counter-current rotation. Scans of rotational profiles vs. resonance location, initial energy, particle loss, pitch, and qm will be presented as will the location of the velocity shear layer its scaling to a reactor.

Practical silicon deposition rules derived from silane monitoring during plasma-enhanced chemical vapor deposition

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bartlome, Richard, E-mail: richard.bartlome@alumni.ethz.ch; De Wolf, Stefaan; Demaurex, Bénédicte

2015-05-28

We clarify the difference between the SiH{sub 4} consumption efficiency η and the SiH{sub 4} depletion fraction D, as measured in the pumping line and the actual reactor of an industrial plasma-enhanced chemical vapor deposition system. In the absence of significant polysilane and powder formation, η is proportional to the film growth rate. Above a certain powder formation threshold, any additional amount of SiH{sub 4} consumed translates into increased powder formation rather than into a faster growing Si film. In order to discuss a zero-dimensional analytical model and a two-dimensional numerical model, we measure η as a function of themore » radio frequency (RF) power density coupled into the plasma, the total gas flow rate, the input SiH{sub 4} concentration, and the reactor pressure. The adjunction of a small trimethylboron flow rate increases η and reduces the formation of powder, while the adjunction of a small disilane flow rate decreases η and favors the formation of powder. Unlike η, D is a location-dependent quantity. It is related to the SiH{sub 4} concentration in the plasma c{sub p}, and to the phase of the growing Si film, whether the substrate is glass or a c-Si wafer. In order to investigate transient effects due to the RF matching, the precoating of reactor walls, or the introduction of a purifier in the gas line, we measure the gas residence time and acquire time-resolved SiH{sub 4} density measurements throughout the ignition and the termination of a plasma.« less

Transportation properties of a high-current magnetically insulated transmission line and dynamics of the electrode plasma

NASA Astrophysics Data System (ADS)

Anan'ev, S. S.; Bakshaev, Yu. L.; Bartov, A. V.; Blinov, P. I.; Dan'ko, S. A.; Zhuzhunashvili, A. I.; Kazakov, E. D.; Kalinin, Yu. G.; Kingsep, A. S.; Korolev, V. D.; Mizhiritskii, V. I.; Smirnov, V. P.; Tkachenko, S. I.; Chernenko, A. S.

2008-07-01

Results are presented from experimental studies of a section of a magnetically insulated transmission line (MITL) with a current density of up to 500 MA/cm2 and linear current density of up to 7 MA/cm (the parameters close to those in a fast-Z-pinch-driven fusion reactor projected at Sandia Laboratories). The experiments were performed in the S-300 facility (3 MA, 0.15 Ω, 100 ns). At high linear current densities, the surface of the ohmically heated MITL electrode can explode and a plasma layer can form near the electrode surface. As a result, the MITL can lose its transmission properties due to the shunting of the vacuum gap by the plasma produced. In this series of experiments, the dynamics of the electrode plasma and the dependence of the transmission properties of the MITL on the material and cleanness of the electrode surface were studied. It is shown experimentally that, when the current with a linear density of up to 7 MA/cm begins to flow along a model MITL, the input and output currents differ by less than 10% over a time interval of up to 230 ns for nickel electrodes and up to 350 ns for a line with a gold central electrode. No effect of the oil film present on the electrode surface on the loss of the transmission properties of the line was observed. It is also shown that electron losses insignificantly contribute to the total current balance. The experimental results are compared with calculations of the electrode explosion and the subsequent expansion of the plasma layer. A conclusion is made that the life-time of the model MITL satisfies the requirements imposed on the transmission lines intended for use in the projected thermonuclear reactor.

Non-Equilibrium Plasma MHD Electrical Power Generation at Tokyo Tech

NASA Astrophysics Data System (ADS)

Murakami, T.; Okuno, Y.; Yamasaki, H.

2008-02-01

This paper reviews the recent activities on radio-frequency (rf) electromagnetic-field-assisted magnetohydrodynamic (MHD) power generation experiments at the Tokyo Institute of Technology. An inductively coupled rf field (13.56 MHz) is continuously supplied to the disk-shaped Hall-type MHD generator. The first part of this paper describes a method of obtaining increased power output from a pure Argon plasma MHD power generator by incorporating an rf power source to preionize and heat the plasma. The rf heating enhances ionization of the Argon and raises the temperature of the free electron population above the nominally low 4500 K temperatures obtained without rf heating. This in turn enhances the plasma conductivity making MHD power generation feasible. We demonstrate an enhanced power output when rf heating is on approximately 5 times larger than the input power of the rf generator. The second part of this paper is a demonstration of a physical phenomenon of the rf-stabilization of the ionization instability, that had been conjectured for some time, but had not been seen experimentally. The rf heating suppresses the ionization instability in the plasma behavior and homogenizes the nonuniformity of the plasma structures. The power-generating performance is significantly improved with the aid of the rf power under wide seeding conditions. The increment of the enthalpy extraction ratio of around 2% is significantly greater than the fraction of the net rf power, that is, 0.16%, to the thermal input.

Experimental and modeling study of the oxidation of acetaldehyde in an atmospheric-pressure pulsed corona discharge

NASA Astrophysics Data System (ADS)

Klett, C.; Touchard, S.; Vega-Gonzalez, A.; Redolfi, M.; Bonnin, X.; Hassouni, K.; Duten, X.

2012-08-01

This paper reports the results obtained for the degradation of acetaldehyde by an atmospheric plasma corona discharge working in a pulsed regime. It was shown that a few hundred ppm of acetaldehyde diluted in a pure N2 gas flow can be removed up to 80% by a discharge fed with an electric power lower than 1 W. Under the same conditions, adding up to 5% of O2 allowed the removal of up to 95% of the initial acetaldehyde. The main identified end products were CO2, CO and methanol. A quasi-homogeneous zero-dimensional chemical model was developed to investigate the respective efficiency of the discharge and post-discharge periods in the global removal of the pollutant. The identified main pathways of acetaldehyde degradation were quenching of N2 metastable states during plasma pulses and oxidation by O and OH radicals during the post-discharge. This latter contribution increased with input power because of ozone accumulation in the gas mixture acting as an additional oxygen reservoir.

Model Predictive Control of the Current Profile and the Internal Energy of DIII-D Plasmas

NASA Astrophysics Data System (ADS)

Lauret, M.; Wehner, W.; Schuster, E.

2015-11-01

For efficient and stable operation of tokamak plasmas it is important that the current density profile and the internal energy are jointly controlled by using the available heating and current-drive (H&CD) sources. The proposed approach is a version of nonlinear model predictive control in which the input set is restricted in size by the possible combinations of the H&CD on/off states. The controller uses real-time predictions over a receding-time horizon of both the current density profile (nonlinear partial differential equation) and the internal energy (nonlinear ordinary differential equation) evolutions. At every time instant the effect of every possible combination of H&CD sources on the current profile and internal energy is evaluated over the chosen time horizon. The combination that leads to the best result, which is assessed by a user-defined cost function, is then applied up until the next time instant. Simulations results based on a control-oriented transport code illustrate the effectiveness of the proposed control method. Supported by the US DOE under DE-FC02-04ER54698 & DE-SC0010661.

NASCAP simulation of PIX 2 experiments

NASA Technical Reports Server (NTRS)

Roche, J. C.; Mandell, M. J.

1985-01-01

The latest version of the NASCAP/LEO digital computer code used to simulate the PIX 2 experiment is discussed. NASCAP is a finite-element code and previous versions were restricted to a single fixed mesh size. As a consequence the resolution was dictated by the largest physical dimension to be modeled. The latest version of NASCAP/LEO can subdivide selected regions. This permitted the modeling of the overall Delta launch vehicle in the primary computational grid at a coarse resolution, with subdivided regions at finer resolution being used to pick up the details of the experiment module configuration. Langmuir probe data from the flight were used to estimate the space plasma density and temperature and the Delta ground potential relative to the space plasma. This information is needed for input to NASCAP. Because of the uncertainty or variability in the values of these parameters, it was necessary to explore a range around the nominal value in order to determine the variation in current collection. The flight data from PIX 2 were also compared with the results of the NASCAP simulation.

Correlation of Magnetic Fields with Solar Wind Plasma Parameters at 1AU

NASA Astrophysics Data System (ADS)

Shen, F.

2017-12-01

The physical parameters of the solar wind observed in-situ near 1AU have been studied for several decades, and relationships between them, such as the positive correlation between the solar wind plasma temperature T and velocity V, and the negative correlation between density N and velocity V, are well known. However, the magnetic field intensity does not appear to be well correlated with any individual plasma parameter. In this paper, we discuss previously under-reported correlations between B and the combined plasma parameters √NV2 as well as between B and √NT. These two correlations are strong during the periods of corotating interaction regions and high speed streams, moderate during intervals of slow solar wind, and rather poor during the passage of interplanetary coronal mass ejections. The results indicate that the magnetic pressure in the solar wind is well correlated both with the plasma dynamic pressure and the thermal pressure. Then, we employ a 3D MHD model to simulate the formation of the relationships between the magnetic strength B and √NV2 as well as √NT observed at 1AU. The inner boundary condition is derived by empirical models, with the magnetic field and density are optional. Five kinds of boundary conditions at the inner boundary of heliosphere are tested. In the cases that the magnetic field is related to speed at the inner boundary, the correlation coefficients between B and √NV2 as well as between B and √NT are even higher than that in the observational results. At 1AU the simulated radial magnetic field shows little latitude dependence, which matches the observation of Ulysses. Most of the modeled characters in these cases are closer to observation than others. This inner boundary condition may more accurately characterize Sun's magnetic influence on the heliosphere. The new input may be able to improve the simulation of CME propagation in the inner heliosphere and the space weather forecasting.

Improved confinement in highly powered high performance scenarios on DIII-D

DOE Office of Scientific and Technical Information (OSTI.GOV)

Petrie, Thomas W.; Osborne, Thomas; Fenstermacher, Max E.

DIII-D has recently demonstrated improved energy confinement by injecting neutral deuterium gas into high performance near-double null divertor (DND) plasmas during high power operation. Representative parameters for these plasmas are: q 95 = 6, P IN up to 15 MW, H 98 = 1.4–1.8, and β N = 2.5–4.0. The ion B xmore » $$\\triangledown$$B direction is away from the primary X-point. While plasma conditions at lower to moderate power input (e.g., 11 MW) are shown to be favorable to successful puff-and-pump radiating divertor applications, particularly when using argon seeds, plasma behavior at higher powers (e.g., ≥14 MW) may make successful puff-and-pump operation more problematic. In contrast to lower powered high performance plasmas, both $$\\tau$$ E and β N in the high power cases (≥14 MW) increased and ELM frequency decreased, as density was raised by deuterium gas injection. Improved performance in the higher power plasmas was tied to higher pedestal pressure, which according to peeling-ballooning mode stability analysis using the ELITE code could increase with density along the kink/peeling stability threshold, while the pedestal pressure gradient in the lower power discharges were limited by the ballooning threshold. This resulted in improved fueling efficiency and ≈10% higher $$\\tau$$ E and β N than is normally observed in comparable high performance plasmas on DIII-D. Applying the puff-and-pump radiating divertor approach at moderate versus high power input is shown to result in a much different evolution in core and pedestal plasma behavior. In conclusion, we find that injecting deuterium gas into these highly powered DND plasmas may open up a new avenue for achieving elevated plasma performance, including better fueling, but the resulting higher density may also complicate application of a radiating divertor approach to heat flux reduction in present-day tokamaks, if scenarios involving second-harmonic electron cyclotron heating are used.« less

Improved confinement in highly powered high performance scenarios on DIII-D

DOE PAGES

Petrie, Thomas W.; Osborne, Thomas; Fenstermacher, Max E.; ...

2017-06-09

DIII-D has recently demonstrated improved energy confinement by injecting neutral deuterium gas into high performance near-double null divertor (DND) plasmas during high power operation. Representative parameters for these plasmas are: q 95 = 6, P IN up to 15 MW, H 98 = 1.4–1.8, and β N = 2.5–4.0. The ion B xmore » $$\\triangledown$$B direction is away from the primary X-point. While plasma conditions at lower to moderate power input (e.g., 11 MW) are shown to be favorable to successful puff-and-pump radiating divertor applications, particularly when using argon seeds, plasma behavior at higher powers (e.g., ≥14 MW) may make successful puff-and-pump operation more problematic. In contrast to lower powered high performance plasmas, both $$\\tau$$ E and β N in the high power cases (≥14 MW) increased and ELM frequency decreased, as density was raised by deuterium gas injection. Improved performance in the higher power plasmas was tied to higher pedestal pressure, which according to peeling-ballooning mode stability analysis using the ELITE code could increase with density along the kink/peeling stability threshold, while the pedestal pressure gradient in the lower power discharges were limited by the ballooning threshold. This resulted in improved fueling efficiency and ≈10% higher $$\\tau$$ E and β N than is normally observed in comparable high performance plasmas on DIII-D. Applying the puff-and-pump radiating divertor approach at moderate versus high power input is shown to result in a much different evolution in core and pedestal plasma behavior. In conclusion, we find that injecting deuterium gas into these highly powered DND plasmas may open up a new avenue for achieving elevated plasma performance, including better fueling, but the resulting higher density may also complicate application of a radiating divertor approach to heat flux reduction in present-day tokamaks, if scenarios involving second-harmonic electron cyclotron heating are used.« less

A Dynamic Coupled Magnetosphere-Ionosphere-Ring Current Model

NASA Astrophysics Data System (ADS)

Pembroke, Asher

In this thesis we describe a coupled model of Earth's magnetosphere that consists of the Lyon-Fedder-Mobarry (LFM) global magnetohydrodynamics (MHD) simulation, the MIX ionosphere solver and the Rice Convection Model (RCM). We report some results of the coupled model using idealized inputs and model parameters. The algorithmic and physical components of the model are described, including the transfer of magnetic field information and plasma boundary conditions to the RCM and the return of ring current plasma properties to the LFM. Crucial aspects of the coupling include the restriction of RCM to regions where field-line averaged plasma-beta ¡=1, the use of a plasmasphere model, and the MIX ionosphere model. Compared to stand-alone MHD, the coupled model produces a substantial increase in ring current pressure and reduction of the magnetic field near the Earth. In the ionosphere, stronger region-1 and region-2 Birkeland currents are seen in the coupled model but with no significant change in the cross polar cap potential drop, while the region-2 currents shielded the low-latitude convection potential. In addition, oscillations in the magnetic field are produced at geosynchronous orbit with the coupled code. The diagnostics of entropy and mass content indicate that these oscillations are associated with low-entropy flow channels moving in from the tail and may be related to bursty bulk flows and bubbles seen in observations. As with most complex numerical models, there is the ongoing challenge of untangling numerical artifacts and physics, and we find that while there is still much room for improvement, the results presented here are encouraging. Finally, we introduce several new methods for magnetospheric visualization and analysis, including a fluid-spatial volume for RCM and a field-aligned analysis mesh for the LFM. The latter allows us to construct novel visualizations of flux tubes, drift surfaces, topological boundaries, and bursty-bulk flows.

Particle tracing modeling of ion fluxes at geosynchronous orbit during substorms

NASA Astrophysics Data System (ADS)

Brito, T. V.; Jordanova, V.; Woodroffe, J. R.; Henderson, M. G.; Morley, S.; Birn, J.

2016-12-01

The SHIELDS project aims to couple a host of different models for different regions of the magnetosphere using different numerical methods such as MHD, PIC and particle tracing, with the ultimate goal of having a more realistic model of the whole magnetospheric environment capturing, as much as possible, the different physics of the various plasma populations. In that context, we present a modeling framework that can be coupled with a global MHD model to calculate particle fluxes in the inner magnetosphere, which can in turn be used to constantly update the input for a ring current model. In that regard, one advantage of that approach over using spacecraft data is that it produces a much better spatial and temporal coverage of the nightside geosynchronous region and thus a possibly more complete input for the ring current model, which will likely produce more accurate global results for the ring current population. In this presentation, we will describe the particle tracing method in more detail, describe the method used to couple it to the BATS-R-US 3D global MHD code, and the method used to update the flux results to the RAM-SCB ring current model. We will also present the simulation results for the July 18, 2013 period, which showed significant substorm activity. We will compare simulated ion fluxes on the nightside magnetosphere with spacecraft observations to gauge how well our simulations are capturing substorm dynamics.

On the Measurement of Electron Temperature by Single Langmuir Probes in High Recycling Divertors

NASA Astrophysics Data System (ADS)

Pitts, Richard; Horacek, Jan; Loarte, Alberto

2000-10-01

Under high recycling and detached conditions, divertor Langmuir probes often yield a significantly higher value of Te than expected. The influence of plasma turbulence and the effect of fast electrons/plasma collisionality are two reasons why this might occur. We concentrate on these two candidates, with particular reference to observations on the TCV tokamak. A systematic study of the effects of noise on simulated probe characteristics at low T_e, shows that the asymmetric, exponential nature of the characteristic favours electron collection such that fluctuations in Vf alone actually tend to reduce the derived Te from that which would otherwise be found. We have also studied the effects of correlated density and potential fluctuations, finding no effect on the fitted T_e. The sheath potential fall energetically filters electrons such that at high densities, the probe measured Te may be characteristic of hotter, more distant zones in the plasma. We use model parallel field profiles of Te and ne generated from B2-Eirene simulations of TCV discharges as input to the analytic theory of Wesson [1] to show how a divertor plate measurement of Te in TCV can exceed the expected value by factors of up to 6 as detachment is approached. [1] J. A. Wesson, Plasma Phys. and Contr. Fusion 37 (1995) 1459

The MHD simulation of interplanetary space and heliosphere by using the boundary conditions of time-varying magnetic field and IPS-based plasma

NASA Astrophysics Data System (ADS)

Hayashi, K.; Tokumaru, M.; Kojima, M.; Fujiki, K.

2008-12-01

We present our new boundary treatment to introduce the temporal variation of the observation-based magnetic field and plasma parameters on the inner boundary sphere (at 30 to 50 Rs) to the MHD simulation of the interplanetary space and the simulation results. The boundary treatment to induce the time-variation of the magnetic field including the radial component is essentially same as shown in our previous AGU meetings and newly modified so that the model can also include the variation of the plasma variables detected by IPS (interplanetary scintillation) observation, a ground-based remote sensing technique for the solar wind plasma. We used the WSO (Wilcox Solar Observatory at Stanford University) for the solar magnetic field input. By using the time-varying boundary condition, smooth variations of heliospheric MHD variables during the several Carrington solar rotation period are obtained. The simulation movie will show how the changes in the inner heliosphere observable by the ground-based instrument propagate outward and affects the outer heliosphere. The simulated MHD variables are compared with the Ulysses in-situ measurement data including ones made during its travel from the Earth to Jupiter for validation, and we obtain better agreements than with the simulation with fixed boundary conditions.

A mechanism of wave drag reduction in the thermal energy deposition experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Markhotok, A., E-mail: amarhotk@phys.washington.edu

2015-06-15

Many experimental studies report reduced wave drag when thermal energy is deposited in the supersonic flow upstream of a body. Though a large amount of research on this topic has been accumulated, the exact mechanism of the drag reduction is still unknown. This paper is to fill the gap in the understanding connecting multiple stages of the observed phenomena with a single mechanism. The proposed model provides an insight on the origin of the chain of subsequent transformations in the flow leading to the reduction in wave drag, such as typical deformations of the front, changes in the gas pressuremore » and density in front of the body, the odd shapes of the deflection signals, and the shock wave extinction in the plasma area. The results of numerical simulation based on the model are presented for three types of plasma parameter distribution. The spherical and cylindrical geometry has been used to match the data with the experimental observations. The results demonstrate full ability of the model to exactly explain all the features observed in the drag reduction experiments. Analytical expressions used in the model allow separating out a number of adjustment parameters that can be used to optimize thermal energy input and thus achieve fundamentally lower drag values than that of conventional approaches.« less

Hall Thruster Thermal Modeling and Test Data Correlation

NASA Technical Reports Server (NTRS)

Myers, James; Kamhawi, Hani; Yim, John; Clayman, Lauren

2016-01-01

The life of Hall Effect thrusters are primarily limited by plasma erosion and thermal related failures. NASA Glenn Research Center (GRC) in cooperation with the Jet Propulsion Laboratory (JPL) have recently completed development of a Hall thruster with specific emphasis to mitigate these limitations. Extending the operational life of Hall thursters makes them more suitable for some of NASA's longer duration interplanetary missions. This paper documents the thermal model development, refinement and correlation of results with thruster test data. Correlation was achieved by minimizing uncertainties in model input and recognizing the relevant parameters for effective model tuning. Throughout the thruster design phase the model was used to evaluate design options and systematically reduce component temperatures. Hall thrusters are inherently complex assemblies of high temperature components relying on internal conduction and external radiation for heat dispersion and rejection. System solutions are necessary in most cases to fully assess the benefits and/or consequences of any potential design change. Thermal model correlation is critical since thruster operational parameters can push some components/materials beyond their temperature limits. This thruster incorporates a state-of-the-art magnetic shielding system to reduce plasma erosion and to a lesser extend power/heat deposition. Additionally a comprehensive thermal design strategy was employed to reduce temperatures of critical thruster components (primarily the magnet coils and the discharge channel). Long term wear testing is currently underway to assess the effectiveness of these systems and consequently thruster longevity.

Electron density and gas density measurements in a millimeter-wave discharge

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schaub, S. C., E-mail: sschaub@mit.edu; Hummelt, J. S.; Guss, W. C.

2016-08-15

Electron density and neutral gas density have been measured in a non-equilibrium air breakdown plasma using optical emission spectroscopy and two-dimensional laser interferometry, respectively. A plasma was created with a focused high frequency microwave beam in air. Experiments were run with 110 GHz and 124.5 GHz microwaves at powers up to 1.2 MW. Microwave pulses were 3 μs long at 110 GHz and 2.2 μs long at 124.5 GHz. Electron density was measured over a pressure range of 25 to 700 Torr as the input microwave power was varied. Electron density was found to be close to the critical density, where the collisional plasma frequency is equal tomore » the microwave frequency, over the pressure range studied and to vary weakly with input power. Neutral gas density was measured over a pressure range from 150 to 750 Torr at power levels high above the threshold for initiating breakdown. The two-dimensional structure of the neutral gas density was resolved. Intense, localized heating was found to occur hundreds of nanoseconds after visible plasma formed. This heating led to neutral gas density reductions of greater than 80% where peak plasma densities occurred. Spatial structure and temporal dynamics of gas heating at atmospheric pressure were found to agree well with published numerical simulations.« less

Strategic Directions in Heliophysics Research Related to Weakly Ionized Plasmas

NASA Technical Reports Server (NTRS)

Spann, James F.

2010-01-01

In 2009, the Heliophysics Division of NASA published its triennial roadmap entitled "Heliophysics; the solar and space physics of a new era." In this document contains a science priority that is recommended that will serve as input into the recently initiated NRC Heliophysics Decadal Survey. The 2009 roadmap includes several science targets recommendations that are directly related to weakly ionized plasmas, including on entitled "Ion-Neutral Coupling in the Atmosphere." This talk will be a brief overview of the roadmap with particular focus on the science targets relevant to weakly ionized plasmas.

Synthetic Plasma Liquid Based Electronic Circuits Realization-A Novel Concept.

PubMed

Pandya, Killol V; Kosta, ShivPrasad

2016-09-01

Biomedical research is contributing significant role in the field of biomedical engineering and applied science. It brings research and innovations to a different level. This study investigated artificial human blood -synthetic plasma liquid as conductive medium. Keeping in mind the conductivity of synthetic plasma, astable multivibrator as well as differential amplifier circuit were demonstrated. The circuits were given normal input voltages at regular temperature and ideal conditions. The result shows desired response which supports the novel concept. For both the circuits, phase shift of 180° achieved by analysing biological electronic circuits.

Full-Process Computer Model of Magnetron Sputter, Part I: Test Existing State-of-Art Components

DOE Office of Scientific and Technical Information (OSTI.GOV)

Walton, C C; Gilmer, G H; Wemhoff, A P

2007-09-26

This work is part of a larger project to develop a modeling capability for magnetron sputter deposition. The process is divided into four steps: plasma transport, target sputter, neutral gas and sputtered atom transport, and film growth, shown schematically in Fig. 1. Each of these is simulated separately in this Part 1 of the project, which is jointly funded between CMLS and Engineering. The Engineering portion is the plasma modeling, in step 1. The plasma modeling was performed using the Object-Oriented Particle-In-Cell code (OOPIC) from UC Berkeley [1]. Figure 2 shows the electron density in the simulated region, using magneticmore » field strength input from experiments by Bohlmark [2], where a scale of 1% is used. Figures 3 and 4 depict the magnetic field components that were generated using two-dimensional linear interpolation of Bohlmark's experimental data. The goal of the overall modeling tool is to understand, and later predict, relationships between parameters of film deposition we can change (such as gas pressure, gun voltage, and target-substrate distance) and key properties of the results (such as film stress, density, and stoichiometry.) The simulation must use existing codes, either open-source or low-cost, not develop new codes. In part 1 (FY07) we identified and tested the best available code for each process step, then determined if it can cover the size and time scales we need in reasonable computation times. We also had to determine if the process steps are sufficiently decoupled that they can be treated separately, and identify any research-level issues preventing practical use of these codes. Part 2 will consider whether the codes can be (or need to be) made to talk to each other and integrated into a whole.« less

Plasma application for detoxification of Jatropha phorbol esters

NASA Astrophysics Data System (ADS)

Kongmany, S.; Matsuura, H.; Furuta, M.; Okuda, S.; Imamura, K.; Maeda, Y.

2013-06-01

Atmospheric pressure non-thermal dielectric barrier discharge (DBD) plasma generated by helium gas at high voltage and input power of about 50 W was first applied to detoxification of Jatropha curcas phorbol esters (J. PEs) as well as standard phorbol ester (4β-12-O-tetradecanoyl phorbol-13-acetate, TPA) in water and methanol. Plasma irradiation on the solution sample was conducted for 15 min. In aqueous solution, only 16% of TPA was degraded and complete degradation of J. PEs was observed. On the contrary, complete degradation of both TPA and J. PEs in methanol was achieved by the same plasma irradiation condition. Hydroxyl radical (•OH) generated by plasma irradiation of the solution is expected as the main radical inducing the degradation of PEs.

Dayside ionosphere of Titan: Impact on calculated plasma densities due to variations in the model parameters

NASA Astrophysics Data System (ADS)

Mukundan, Vrinda; Bhardwaj, Anil

2018-01-01

A one dimensional photochemical model for the dayside ionosphere of Titan has been developed for calculating the density profiles of ions and electrons under steady state photochemical equilibrium condition. We concentrated on the T40 flyby of Cassini orbiter and used the in-situ measurements from instruments onboard Cassini as input to the model. An energy deposition model is employed for calculating the attenuated photon flux and photoelectron flux at different altitudes in Titan's ionosphere. We used the Analytical Yield Spectrum approach for calculating the photoelectron fluxes. Volume production rates of major primary ions, like, N2+, N+ , CH4+, CH3+, etc due to photon and photoelectron impact are calculated and used as input to the model. The modeled profiles are compared with the Cassini Ion Neutral Mass Spectrometer (INMS) and Langmuir Probe (LP) measurements. The calculated electron density is higher than the observation by a factor of 2 to 3 around the peak. We studied the impact of different model parameters, viz. photoelectron flux, ion production rates, electron temperature, dissociative recombination rate coefficients, neutral densities of minor species, and solar flux on the calculated electron density to understand the possible reasons for this discrepancy. Recent studies have shown that there is an overestimation in the modeled photoelectron flux and N2+ ion production rates which may contribute towards this disagreement. But decreasing the photoelectron flux (by a factor of 3) and N2+ ion production rate (by a factor of 2) decreases the electron density only by 10 to 20%. Reduction in the measured electron temperature by a factor of 5 provides a good agreement between the modeled and observed electron density. The change in HCN and NH3 densities affects the calculated densities of the major ions (HCNH+ , C2H5+, and CH5+); however the overall impact on electron density is not appreciable ( < 20%). Even though increasing the dissociative recombination rate coefficients of the ions C2H5+ and CH5+ by a factor of 10 reduces the difference between modeled and observed densities of the major ions, the modeled electron density is still higher than the observation by ∼ 60% at the peak. We suggest that there might be some unidentified chemical reactions that may account for the additional loss of plasma in Titan's ionosphere.

The temperature structure, mass, and energy flow in the corona and inner solar wind

NASA Technical Reports Server (NTRS)

Withbroe, George L.

1988-01-01

Remote-sensing and in situ data are used to constrain a radiative energy balance model in order to study the radial variations of coronal temperatures, densities, and outflow speeds in several types of coronal holes and in an unstructured quiet region of the corona. A one-fluid solar wind model is used which takes into account the effects of radiative and inward conductive losses in the low corona and the chromospheric-coronal transition region. The results show that the total nonradiative energy input in magnetically open coronal regions is 5 + or - 10 to the 5th ergs/sq cm, and that most of the energy heating the coronal plasma is dissipated within 2 solar radii of the solar surface.

Investigating the collision energy dependence of η /s in the beam energy scan at the BNL Relativistic Heavy Ion Collider using Bayesian statistics

NASA Astrophysics Data System (ADS)

Auvinen, Jussi; Bernhard, Jonah E.; Bass, Steffen A.; Karpenko, Iurii

2018-04-01

We determine the probability distributions of the shear viscosity over the entropy density ratio η /s in the quark-gluon plasma formed in Au + Au collisions at √{sN N}=19.6 ,39 , and 62.4 GeV , using Bayesian inference and Gaussian process emulators for a model-to-data statistical analysis that probes the full input parameter space of a transport + viscous hydrodynamics hybrid model. We find the most likely value of η /s to be larger at smaller √{sN N}, although the uncertainties still allow for a constant value between 0.10 and 0.15 for the investigated collision energy range.

High Power Light Gas Helicon Plasma Source for VASIMR

NASA Technical Reports Server (NTRS)

Squire, Jared P.; Chang-Diaz, Franklin R.; Glover, Timothy W.; Jacobson, Verlin T.; Baity, F. Wally; Carter, Mark D.; Goulding, Richard H.

2004-01-01

In the Advanced Space Propulsion Laboratory (ASPL) helicon experiment (VX-10) we have measured a plasma flux to input gas rate ratio near 100% for both helium and deuterium at power levels up to 10 kW. Recent results at Oak Ridge National Laboratory (ORNL) show enhanced efficiency operation with a high power density, over 5 kW in a 5 cm diameter tube. Our helicon is presently 9 cm in diameter and operates up to 10 kW of input power. The data here uses a Boswell double-saddle antenna design with a magnetic cusp just upstream of the antenna. Similar to ORNL, for deuterium at near 10 kW, we find an enhanced performance of operation at magnetic fields above the lower hybrid matching condition.

Testing and evaluation of the LES-6 pulsed plasma thruster by means of a torsion pendulum system

NASA Technical Reports Server (NTRS)

Hamidian, J. P.; Dahlgren, J. B.

1973-01-01

Performance characteristics of the LES-6 pulsed plasma thruster over a range of input conditions were investigated by means of a torsion pendulum system. Parameters of particular interest included the impulse bit and time average thrust (and their repeatability), specific impulse, mass ablated per discharge, specific thrust, energy per unit area, efficiency, and variation of performance with ignition command rate. Intermittency of the thruster as affected by input energy and igniter resistance were also investigated. Comparative experimental data correlation with the data presented. The results of these tests indicate that the LES-6 thruster, with some identifiable design improvements, represents an attractive reaction control thruster for attitude contol applications on long-life spacecraft requiring small metered impulse bits for precise pointing control of science instruments.

Modeling of potential TAE-induced beam ion loss from NSTX-U plasmas

NASA Astrophysics Data System (ADS)

Darrow, Douglass; Fredrickson, Eric; Podesta, Mario; White, Roscoe; Liu, Deyong

2015-11-01

NSTX-U will add three additional neutral beam sources, whose tangency radii of 1.1, 1.2, and 1.3 m, are significantly larger than the 0.5, 0.6, and 0.7 m tangency radii of the neutral beams previously used in NSTX. These latter beams will also be used in NSTX-U. Here, we attempt to formulate an estimate of the propensity of the beam ions from all the various sources to be lost under a range of NSTX-U plasma conditions. This estimation is based upon TRANSP calculations of beam ion deposition in phase space, and the location of the FLR-corrected loss boundary in that phase space. Since TAEs were a prominent driver of beam ion loss in NSTX, we incorporate their effects through the following process: NOVA modeling of TAEs in the anticipated NSTX-U plasma conditions gives the mode numbers, frequencies, and mode structures that are likely to occur. Using this information as inputs to the guiding center ORBIT code, it is possible to find resonant surfaces in the same phase space along which beam ions would be able to diffuse under the influence of the modes. The degree to which these resonant surfaces intersect both the beam deposition volume and the orbit loss boundary should then give a sense of the propensity of that beam population to be lost from the plasma. Work supported by US DOE contracts DE-AC0209CH11466, DE-FG02-06ER54867, and DE-FG03-02ER54681.

A non-LTE analysis of high energy density Kr plasmas on Z and NIF

NASA Astrophysics Data System (ADS)

Dasgupta, A.; Clark, R. W.; Ouart, N.; Giuliani, J.; Velikovich, A.; Ampleford, D. J.; Hansen, S. B.; Jennings, C.; Harvey-Thompson, A. J.; Jones, B.; Flanagan, T. M.; Bell, K. S.; Apruzese, J. P.; Fournier, K. B.; Scott, H. A.; May, M. J.; Barrios, M. A.; Colvin, J. D.; Kemp, G. E.

2016-10-01

Multi-keV X-ray radiation sources have a wide range of applications, from biomedical studies and research on thermonuclear fusion to materials science and astrophysics. The refurbished Z pulsed power machine at the Sandia National Laboratories produces intense multi-keV X-rays from argon Z-pinches, but for a krypton Z-pinch, the yield decreases much faster with atomic number ZA than similar sources on the National Ignition Facility (NIF) laser at the Lawrence Livermore National Laboratory. To investigate whether fundamental energy deposition differences between pulsed power and lasers could account for the yield differences, we consider the Kr plasma on the two machines. The analysis assumes the plasma not in local thermodynamic equilibrium, with a detailed coupling between the hydrodynamics, the radiation field, and the ionization physics. While for the plasma parameters of interest the details of krypton's M-shell are not crucial, both the L-shell and the K-shell must be modeled in reasonable detail, including the state-specific dielectronic recombination processes that significantly affect Kr's ionization balance and the resulting X-ray spectrum. We present a detailed description of the atomic model, provide synthetic K- and L-shell spectra, and compare these with the available experimental data from the Z-machine and from NIF to show that the K-shell yield behavior versus ZA is indeed related to the energy input characteristics. This work aims at understanding the probable causes that might explain the differences in the X-ray conversion efficiencies of several radiation sources on Z and NIF.

Adenosine 2A receptor occupancy by tozadenant and preladenant in rhesus monkeys.

PubMed

Barret, Olivier; Hannestad, Jonas; Alagille, David; Vala, Christine; Tavares, Adriana; Papin, Caroline; Morley, Thomas; Fowles, Krista; Lee, Hsiaoju; Seibyl, John; Tytgat, Dominique; Laruelle, Marc; Tamagnan, Gilles

2014-10-01

Motor symptoms in Parkinson disease (PD) are caused by a loss of dopamine input from the substantia nigra to the striatum. Blockade of adenosine 2A (A(2A)) receptors facilitates dopamine D(2) receptor function. In phase 2 clinical trials, A(2A) antagonists (istradefylline, preladenant, and tozadenant) improved motor function in PD. We developed a new A(2A) PET radiotracer, (18)F-MNI-444, and used it to investigate the relationship between plasma levels and A(2A) occupancy by preladenant and tozadenant in nonhuman primates (NHP). A series of 20 PET experiments was conducted in 5 adult rhesus macaques. PET data were analyzed with both plasma-input (Logan graphical analysis) and reference-region-based (simplified reference tissue model and noninvasive Logan graphical analysis) methods. Whole-body PET images were acquired for radiation dosimetry estimates. Human pharmacokinetic parameters for tozadenant and preladenant were used to predict A(2A) occupancy in humans, based on median effective concentration (EC(50)) values estimated from the NHP PET measurements. (18)F-MNI-444 regional uptake was consistent with A(2A) receptor distribution in the brain. Selectivity was demonstrated by dose-dependent blocking by tozadenant and preladenant. The specific-to-nonspecific ratio was superior to that of other A(2A) PET radiotracers. Pharmacokinetic modeling predicted that tozadenant and preladenant may have different profiles of A(2A) receptor occupancy in humans. (18)F-MNI-444 appears to be a better PET radiotracer for A(2A) imaging than currently available radiotracers. Assuming that EC(50) in humans is similar to that in NHP, it appears that tozadenant will provide a more sustained A(2A) receptor occupancy than preladenant in humans at clinically tested doses. © 2014 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

Isotopic identification of natural vs. anthropogenic lead sources in marine sediments from the inner Ría de Vigo (NW Spain).

PubMed

Álvarez-Iglesias, P; Rubio, B; Millos, J

2012-10-15

San Simón Bay, the inner part of the Ría de Vigo (NW Spain), an area previously identified as highly polluted by Pb, was selected for the application of Pb stable isotope ratios as a fingerprinting tool in subtidal and intertidal sediment cores. Lead isotopic ratios were determined by inductively coupled plasma mass spectrometry on extracts from bulk samples after total acid digestion. Depth-wise profiles of (206)Pb/(207)Pb, (206)Pb/(204)Pb, (207)Pb/(204)Pb, (208)Pb/(204)Pb and (208)Pb/(207)Pb ratios showed, in general, an upward decrease for both intertidal and subtidal sediments as a consequence of the anthropogenic activities over the last century, or centuries. Waste channel samples from a nearby ceramic factory showed characteristic Pb stable isotope ratios different from those typical of coal and petrol. Natural isotope ratios from non-polluted samples were established for the study area, differentiating sediments from granitic or schist-gneiss sources. A binary mixing model employed on the polluted samples allowed estimating the anthropogenic inputs to the bay. These inputs represented between 25 and 98% of Pb inputs in intertidal samples, and 9-84% in subtidal samples, their contributions varying with time. Anthropogenic sources were apportioned according to a three-source model. Coal combustion-related emissions were the main anthropogenic source Pb to the bay (60-70%) before the establishment of the ceramic factory in the area (in the 1970s) which has since constituted the main source (95-100%), followed by petrol-related emissions. The Pb inputs history for the intertidal area was determined for the 20th century, and, for the subtidal area, the 19th and 20th centuries. Copyright © 2012 Elsevier B.V. All rights reserved.

Atmospheric plasma generation for LCD panel cleaning

NASA Astrophysics Data System (ADS)

Kim, Gyu-Sik; Won, Chung-Yuen; Choi, Ju-Yeop; Yim, C. H.

2007-12-01

UV lamp systems have been used for cleaning of display panels of TFT LCD or Plasma Display Panel (PDP). However, the needs for high efficient cleaning and low cost made high voltage plasma cleaning techniques to be developed and to be improved. Dielectric-barrier discharges (DBDs), also referred to as barrier discharges or silent discharges have for a long time been exclusively related to ozone generation. In this paper, a 6kW high voltage plasma power supply system was developed for LCD cleaning. The -phase input voltage is rectified and then inverter system is used to make a high frequency pulse train, which is rectified after passing through a high-power transformer. Finally, bi-directional high voltage pulse switching circuits are used to generate the high voltage plasma. Some experimental results showed the usefulness of atmospheric plasma for LCD panel cleaning.

The effect of pre-plasma formation under nonlocal transport conditions for ultra-relativistic laser-plasma interaction

NASA Astrophysics Data System (ADS)

Holec, M.; Nikl, J.; Vranic, M.; Weber, S.

2018-04-01

Interaction of high-power lasers with solid targets is in general strongly affected by the limited contrast available. The laser pre-pulse ionizes the target and produces a pre-plasma which can strongly modify the interaction of the main part of the laser pulse with the target. This is of particular importance for future experiments which will use laser intensities above 1021 W cm-2 and which are subject to the limited contrast. As a consequence the main part of the laser pulse will be modified while traversing the pre-plasma, interacting with it partially. A further complication arises from the fact that the interaction of a high-power pre-pulse with solid targets very often takes place under nonlocal transport conditions, i.e. the characteristic mean-free-path of the particles and photons is larger than the characteristic scale-lengths of density and temperature. The classical diffusion treatment of radiation and heat transport in the hydrodynamic model is then insufficient for the description of the pre-pulse physics. These phenomena also strongly modify the formation of the pre-plasma which in turn affects the propagation of the main laser pulse. In this paper nonlocal radiation-hydrodynamic simulations are carried out and serve as input for subsequent kinetic simulations of ultra-high intensity laser pulses interacting with the plasma in the ultra-relativistic regime. It is shown that the results of the kinetic simulations differ considerably whether a diffusive or nonlocal transport is used for the radiation-hydrodynamic simulations.

Modeling of limiter heat loads and impurity transport in Wendelstein 7-X startup plasmas

NASA Astrophysics Data System (ADS)

Effenberg, Florian; Feng, Y.; Frerichs, H.; Schmitz, O.; Hoelbe, H.; Koenig, R.; Krychowiak, M.; Pedersen, T. S.; Bozhenkov, S.; Reiter, D.

2015-11-01

The quasi-isodynamic stellarator Wendelstein 7-X starts plasma operation in a limiter configuration. The field consists of closed magnetic flux surfaces avoiding magnetic islands in the plasma boundary. Because of the small size of the limiters and the absence of wall-protecting elements in this phase, limiter heat loads and impurity generation due to plasma surface interaction become a concern. These issues are studied with the 3D fluid plasma edge and kinetic neutral transport code EMC3-Eirene. It is shown that the 3D SOL consists of three separate helical magnetic flux bundles of different field line connection lengths. A density scan at input power of 4MW reveals a strong modulation of the plasma paramters with the connection length. The limiter peak heat fluxes drop from 14 MWm-2 down to 10 MWm-2 with raising the density from 1 ×1018m-3 to 1.9 ×1019m-3, accompanied by an increase of the heat flux channel widths λq. Radiative power losses can help to avoid thermal overloads of the limiters at the upper margin of the heating power. The power removal feasibility of the intrinsic carbon and other extrinsic light impurities via active gas injection is discussed as a preparation of this method for island divertor operation. Work supported in part by start up funds of the Department of Engineering Physics at the University of Wisconsin - Madison, USA and by the U.S. Department of Energy under grant DE-SC0013911.

Numerical investigation of the electric field distribution and the power deposition in the resonant cavity of a microwave electrothermal thruster

NASA Astrophysics Data System (ADS)

Yildiz, Mehmet Serhan; Celik, Murat

2017-04-01

Microwave electrothermal thruster (MET), an in-space propulsion concept, uses an electromagnetic resonant cavity as a heating chamber. In a MET system, electromagnetic energy is converted to thermal energy via a free floating plasma inside a resonant cavity. To optimize the power deposition inside the cavity, the factors that affect the electric field distribution and the resonance conditions must be accounted for. For MET thrusters, the length of the cavity, the dielectric plate that separates the plasma zone from the antenna, the antenna length and the formation of a free floating plasma have direct effects on the electromagnetic wave transmission and thus the power deposition. MET systems can be tuned by adjusting the lengths of the cavity or the antenna. This study presents the results of a 2-D axis symmetric model for the investigation of the effects of cavity length, antenna length, separation plate thickness, as well as the presence of free floating plasma on the power absorption. Specifically, electric field distribution inside the resonant cavity is calculated for a prototype MET system developed at the Bogazici University Space Technologies Laboratory. Simulations are conducted for a cavity fed with a constant power input of 1 kW at 2.45 GHz using COMSOL Multiphysics commercial software. Calculations are performed for maximum plasma electron densities ranging from 1019 to 1021 #/m3. It is determined that the optimum antenna length changes with changing plasma density. The calculations show that over 95% of the delivered power can be deposited to the plasma when the system is tuned by adjusting the cavity length.

Optical emission diagnostics of plasmas in chemical vapor deposition of single-crystal diamond

DOE PAGES

Hemawan, Kadek W.; Hemley, Russell J.

2015-08-03

Here, a key aspect of single crystal diamond growth via microwave plasma chemical vapor deposition is in-process control of the local plasma-substrate environment, that is, plasma gas phase concentrations of activated species at the plasma boundary layer near the substrate surface. Emission spectra of the plasma relative to the diamond substrate inside the microwave plasma reactor chamber have been analyzed via optical emission spectroscopy. The spectra of radical species such as CH, C 2, and H (Balmer series) important for diamond growth were found to be more depndent on operating pressure than on microwave power. Plasma gas temperatures were calculatedmore » from measurements of the C 2 Swan band (d 3Π → a 3Π transition) system. The plasma gas temperature ranges from 2800 to 3400 K depending on the spatial location of the plasma ball, microwave power and operating pressure. Addition of Ar into CH 4 + H 2 plasma input gas mixture has little influence on the Hα, Hβ, and Hγ intensities and single-crystal diamond growth rates.« less

Plasma-Based Water Treatment: Efficient Transformation of Perfluoroalkyl Substances in Prepared Solutions and Contaminated Groundwater.

PubMed

Stratton, Gunnar R; Dai, Fei; Bellona, Christopher L; Holsen, Thomas M; Dickenson, Eric R V; Mededovic Thagard, Selma

2017-02-07

A process based on electrical discharge plasma was tested for the transformation of perfluorooctanoic acid (PFOA). The plasma-based process was adapted for two cases, high removal rate and high removal efficiency. During a 30 min treatment, the PFOA concentration in 1.4 L of aqueous solutions was reduced by 90% with the high rate process (76.5 W input power) and 25% with the high efficiency process (4.1 W input power). Both achieved remarkably high PFOA removal and defluorination efficiencies compared to leading alternative technologies. The high efficiency process was also used to treat groundwater containing PFOA and several cocontaminants including perfluorooctanesulfonate (PFOS), demonstrating that the process was not significantly affected by cocontaminants and that the process was capable of rapidly degrading PFOS. Preliminary investigation into the byproducts showed that only about 10% of PFOA and PFOS is converted into shorter-chain perfluoroalkyl acids (PFAAs). Investigation into the types of reactive species involved in primary reactions with PFOA showed that hydroxyl and superoxide radicals, which are typically the primary plasma-derived reactive species, play no significant role. Instead, scavenger experiments indicated that aqueous electrons account for a sizable fraction of the transformation, with free electrons and/or argon ions proposed to account for the remainder.

Slot-Antenna/Permanent-Magnet Device for Generating Plasma

NASA Technical Reports Server (NTRS)

Foster, John E.

2007-01-01

A device that includes a rectangular-waveguide/slot-antenna structure and permanent magnets has been devised as a means of generating a substantially uniform plasma over a relatively large area, using relatively low input power and a low gas flow rate. The device utilizes electron cyclotron resonance (ECR) excited by microwave power to efficiently generate plasma in a manner that is completely electrodeless in the sense that, in principle, there is no electrical contact between the plasma and the antenna. Plasmas generated by devices like this one are suitable for use as sources of ions and/or electrons for diverse material-processing applications (e.g., etching or deposition) and for ion thrusters. The absence of plasma/electrode contact essentially prevents plasma-induced erosion of the antenna, thereby also helping to minimize contamination of the plasma and of objects exposed to the plasma. Consequently, the operational lifetime of the rectangular-waveguide/ slot-antenna structure is long and the lifetime of the plasma source is limited by the lifetime of the associated charged-particle-extraction grid (if used) or the lifetime of the microwave power source. The device includes a series of matched radiating slot pairs that are distributed along the length of a plasma-source discharge chamber (see figure). This arrangement enables the production of plasma in a distributed fashion, thereby giving rise to a uniform plasma profile. A uniform plasma profile is necessary for uniformity in any electron- or ion-extraction electrostatic optics. The slotted configuration of the waveguide/ antenna structure makes the device scalable to larger areas and higher powers. All that is needed for scaling up is the attachment of additional matched radiating slots along the length of the discharge chamber. If it is desired to make the power per slot remain constant in scaling up, then the input microwave power must be increased accordingly. Unlike in prior ECR microwave plasma-generating devices, there is no need for an insulating window on the antenna. Such windows are sources of contamination and gradually become ineffective as they become coated with erosion products over time. These characteristics relegate prior ECR microwave plasma-generating devices to non-ion beam, non-deposition plasma applications. In contrast, the lack of need for an insulating window in the present device makes it possible to use the device in both ion-beam (including deposition) and electron-beam applications. The device is designed so that ECR takes place above each slot and the gradient of the magnetic field at each slot is enough to prevent backflow of plasma.

Advantages of a dual-tracer model over reference tissue models for binding potential measurement in tumors

PubMed Central

Tichauer, K M; Samkoe, K S; Klubben, W S; Hasan, T; Pogue, B W

2012-01-01

The quantification of tumor molecular expression in vivo could have a significant impact for informing and monitoring immerging targeted therapies in oncology. Molecular imaging of targeted tracers can be used to quantify receptor expression in the form of a binding potential (BP) if the arterial input curve or a surrogate of it is also measured. However, the assumptions of the most common approaches (reference tissue models) may not be valid for use in tumors. In this study, the validity of reference tissue models is investigated for use in tumors experimentally and in simulations. Three different tumor lines were grown subcutaneously in athymic mice and the mice were injected with a mixture of an epidermal growth factor receptor- (EGFR-) targeted fluorescent tracer and an untargeted fluorescent tracer. A one-compartment plasma input model demonstrated that the transport kinetics of both tracers were significantly different between tumors and all potential reference tissues, and using the reference tissue model resulted in a theoretical underestimation in BP of 50 ± 37%. On the other hand, the targeted and untargeted tracers demonstrated similar transport kinetics, allowing a dual-tracer approach to be employed to accurately estimate binding potential (with a theoretical error of 0.23 ± 9.07%). These findings highlight the potential for using a dual-tracer approach to quantify receptor expression in tumors with abnormal hemodynamics, possibly to inform the choice or progress of molecular cancer therapies. PMID:23022732

Multiobjective Optimization of Atmospheric Plasma Spray Process Parameters to Deposit Yttria-Stabilized Zirconia Coatings Using Response Surface Methodology

NASA Astrophysics Data System (ADS)

Ramachandran, C. S.; Balasubramanian, V.; Ananthapadmanabhan, P. V.

2011-03-01

Atmospheric plasma spraying is used extensively to make Thermal Barrier Coatings of 7-8% yttria-stabilized zirconia powders. The main problem faced in the manufacture of yttria-stabilized zirconia coatings by the atmospheric plasma spraying process is the selection of the optimum combination of input variables for achieving the required qualities of coating. This problem can be solved by the development of empirical relationships between the process parameters (input power, primary gas flow rate, stand-off distance, powder feed rate, and carrier gas flow rate) and the coating quality characteristics (deposition efficiency, tensile bond strength, lap shear bond strength, porosity, and hardness) through effective and strategic planning and the execution of experiments by response surface methodology. This article highlights the use of response surface methodology by designing a five-factor five-level central composite rotatable design matrix with full replication for planning, conduction, execution, and development of empirical relationships. Further, response surface methodology was used for the selection of optimum process parameters to achieve desired quality of yttria-stabilized zirconia coating deposits.

Folded waveguide coupler

DOEpatents

Owens, Thomas L.

1988-03-01

A resonant cavity waveguide coupler for ICRH of a magnetically confined plasma. The coupler consists of a series of inter-leaved metallic vanes disposed withn an enclosure analogous to a very wide, simple rectangular waveguide that has been "folded" several times. At the mouth of the coupler, a polarizing plate is provided which has coupling apertures aligned with selected folds of the waveguide through which rf waves are launched with magnetic fields of the waves aligned in parallel with the magnetic fields confining the plasma being heated to provide coupling to the fast magnetosonic wave within the plasma in the frequency usage of from about 50-200 mHz. A shorting plate terminates the back of the cavity at a distance approximately equal to one-half the guide wavelength from the mouth of the coupler to ensure that the electric field of the waves launched through the polarizing plate apertures are small while the magnetic field is near a maximum. Power is fed into the coupler folded cavity by means of an input coaxial line feed arrangement at a point which provides an impedance match between the cavity and the coaxial input line.

Measurement of the surface charge accumulation using anodic aluminum oxide(AAO) structure in an inductively coupled plasma

NASA Astrophysics Data System (ADS)

Park, Ji-Hwan; Oh, Seung-Ju; Lee, Hyo-Chang; Kim, Yu-Sin; Kim, Young-Cheol; Kim, June Young; Ha, Chang-Seoung; Kwon, Soon-Ho; Lee, Jung-Joong; Chung, Chin-Wook

2014-10-01

As the critical dimension of the nano-device shrinks, an undesired etch profile occurs during plasma etch process. One of the reasons is the local electric field due to the surface charge accumulation. To demonstrate the surface charge accumulation, an anodic aluminum oxide (AAO) membrane which has high aspect ratio is used. The potential difference between top electrode and bottom electrode in an anodic aluminum oxide contact structure is measured during inductively coupled plasma exposure. The voltage difference is changed with external discharge conditions, such as gas pressure, input power, and gas species and the result is analyzed with the measured plasma parameters.

Flutriciclamide (18F-GE180) PET: First-in-Human PET Study of Novel Third-Generation In Vivo Marker of Human Translocator Protein.

PubMed

Fan, Zhen; Calsolaro, Valeria; Atkinson, Rebecca A; Femminella, Grazia D; Waldman, Adam; Buckley, Christopher; Trigg, William; Brooks, David J; Hinz, Rainer; Edison, Paul

2016-11-01

Neuroinflammation is associated with neurodegenerative disease. PET radioligands targeting the 18-kDa translocator protein (TSPO) have been used as in vivo markers of neuroinflammation, but there is an urgent need for novel probes with improved signal-to-noise ratio. Flutriciclamide ( 18 F-GE180) is a recently developed third-generation TSPO ligand. In this first study, we evaluated the optimum scan duration and kinetic modeling strategies for 18 F-GE180 PET in (older) healthy controls. Ten healthy controls, 6 TSPO high-affinity binders, and 4 mixed-affinity binders were recruited. All subjects underwent detailed neuropsychologic tests, MRI, and a 210-min 18 F-GE180 dynamic PET/CT scan using metabolite-corrected arterial plasma input function. We evaluated 5 different kinetic models: irreversible and reversible 2-tissue-compartment models, a reversible 1-tissue model, and 2 models with an extra irreversible vascular compartment. The minimal scan duration was established using 210-min scan data. The feasibility of generating parametric maps was also investigated using graphical analysis. 18 F-GE180 concentration was higher in plasma than in whole blood during the entire scan duration. The volume of distribution (V T ) was 0.17 in high-affinity binders and 0.12 in mixed-affinity binders using the kinetic model. The model that best represented brain 18 F-GE180 kinetics across regions was the reversible 2-tissue-compartment model (2TCM4k), and 90 min resulted as the optimum scan length required to obtain stable estimates. Logan graphical analysis with arterial input function gave a V T highly consistent with V T in the kinetic model, which could be used for voxelwise analysis. We report for the first time, to our knowledge, the kinetic properties of the novel third-generation TSPO PET ligand 18 F-GE180 in humans: 2TCM4k is the optimal method to quantify the brain uptake, 90 min is the optimal scan length, and the Logan approach could be used to generate parametric maps. Although these control subjects have shown relatively low V T , the methodology presented here forms the basis for quantification for future PET studies using 18 F-GE180 in different pathologies. © 2016 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

Near Real Time Tools for ISS Plasma Science and Engineering Applications

NASA Technical Reports Server (NTRS)

Minow, Joseph I.; Willis, Emily M.; Parker, Linda Neergaard; Shim, Ja Soon; Kuznetsova, Maria M.; Pulkkinen, Antti, A.

2013-01-01

The International Space Station (ISS) program utilizes a plasma environment forecast for estimating electrical charging hazards for crews during extravehicular activity (EVA). The process uses ionospheric electron density (Ne) and temperature (Te) measurements from the ISS Floating Potential Measurement Unit (FPMU) instrument suite with the assumption that the plasma conditions will remain constant for one to fourteen days with a low probability for a space weather event which would significantly change the environment before an EVA. FPMU data is typically not available during EVA's, therefore, the most recent FPMU data available for characterizing the state of the ionosphere during EVA is typically a day or two before the start of an EVA or after the EVA has been completed. Three near real time space weather tools under development for ISS applications are described here including: (a) Ne from ground based ionosonde measurements of foF2 (b) Ne from near real time satellite radio occultation measurements of electron density profiles (c) Ne, Te from a physics based ionosphere model These applications are used to characterize the ISS space plasma environment during EVA periods when FPMU data is not available, monitor for large changes in ionosphere density that could render the ionosphere forecast and plasma hazard assessment invalid, and validate the "persistence of conditions" forecast assumption. In addition, the tools are useful for providing space environment input to science payloads on ISS and anomaly investigations during periods the FPMU is not operating.

Pulling it all together: the self-consistent distribution of neutral tori in Saturn's Magnetosphere based on all Cassini observations

NASA Astrophysics Data System (ADS)

Smith, H. T.; Richardson, J. D.

2017-12-01

Saturn's magnetosphere is unique in that the plumes from the small icy moon, Enceladus, serve at the primary source for heavy particles in Saturn's magnetosphere. The resulting co-orbiting neutral particles interact with ions, electrons, photons and other neutral particles to generate separate H2O, OH and O tori. Characterization of these toroidal distributions is essential for understanding Saturn magnetospheric sources, composition and dynamics. Unfortunately, limited direct observations of these features are available so modeling is required. A significant modeling challenge involves ensuring that either the plasma and neutral particle populations are not simply input conditions but can provide feedback to each population (i.e. are self-consistent). Jurac and Richardson (2005) executed such a self-consistent model however this research was performed prior to the return of Cassini data. In a similar fashion, we have coupled a 3-D neutral particle model (Smith et al. 2004, 2005, 2006, 2007, 2009, 2010) with a plasma transport model (Richardson 1998; Richardson & Jurac 2004) to develop a self-consistent model which is constrained by all available Cassini observations and current findings on Saturn's magnetosphere and the Enceladus plume source resulting in much more accurate neutral particle distributions. We present a new self-consistent model of the distribution of the Enceladus-generated neutral tori that is validated by all available observations. We also discuss the implications for source rate and variability.

Two Way Coupling RAM-SCB to the Space Weather Modeling Framework

NASA Astrophysics Data System (ADS)

Welling, D. T.; Jordanova, V. K.; Zaharia, S. G.; Toth, G.

2010-12-01

The Ring current Atmosphere interaction Model with Self-Consistently calculated 3D Magnetic field (RAM-SCB) has been used to successfully study inner magnetosphere dynamics during different solar wind and magnetosphere conditions. Recently, one way coupling of RAM-SCB with the Space Weather Modeling Framework (SWMF) has been achieved to replace all data or empirical inputs with those obtained through first-principles-based codes: magnetic field and plasma flux outer boundary conditions are provided by the Block Adaptive Tree Solar wind Roe-type Upwind Scheme (BATS-R-US) MHD code, convection electric field is provided by the Ridley Ionosphere Model (RIM), and ion composition is provided by the Polar Wind Outflow Model (PWOM) combined with a multi-species MHD approach. These advances, though creating a powerful inner magnetosphere virtual laboratory, neglect the important mechanisms through which the ring current feeds back into the whole system, primarily the stretching of the magnetic field lines and shielding of the convection electric field through strong region two Field Aligned Currents (FACs). In turn, changing the magnetosphere in this way changes the evolution of the ring current. To address this shortcoming, the coupling has been expanded to include feedback from RAM-SCB to the other coupled codes: region two FACs are returned to the RIM while total plasma pressure is used to nudge the MHD solution towards the RAM-SCB values. The impacts of the two way coupling are evaluated on three levels: the global magnetospheric level, focusing on the impact on the ionosphere and the shape of the magnetosphere, the regional level, examining the impact on the development of the ring current in terms of energy density, anisotropy, and plasma distribution, and the local level to compare the new results to in-situ measurements of magnetic and electric field and plasma. The results will also be compared to past simulations using the one way coupling and no coupling whatsoever. This work is the first to fully couple an anisotropic kinetic ring current code with a self-consistently calculated magnetic field to a set of global models.

Two way coupling RAM-SCB to the space weather modeling framework

DOE Office of Scientific and Technical Information (OSTI.GOV)

Welling, Daniel T; Jordanova, Vania K; Zaharia, Sorin G

The Ring current Atmosphere interaction Model with Self-Consistently calculated 3D Magnetic field (RAM-SCB) has been used to successfully study inner magnetosphere dynamics during different solar wind and magnetosphere conditions. Recently, one way coupling of RAM-SCB with the Space Weather Modeling Framework (SWMF) has been achieved to replace all data or empirical inputs with those obtained through first-principles-based codes: magnetic field and plasma flux outer boundary conditions are provided by the Block Adaptive Tree Solar wind Roe-type Upwind Scheme (BATS-R-US) MHO code, convection electric field is provided by the Ridley Ionosphere Model (RIM), and ion composition is provided by the Polarmore » Wind Outflow Model (PWOM) combined with a multi-species MHO approach. These advances, though creating a powerful inner magnetosphere virtual laboratory, neglect the important mechanisms through which the ring current feeds back into the whole system, primarily the stretching of the magnetic field lines and shielding of the convection electric field through strong region two Field Aligned Currents (FACs). In turn, changing the magnetosphere in this way changes the evolution of the ring current. To address this shortcoming, the coupling has been expanded to include feedback from RAM-SCB to the other coupled codes: region two FACs are returned to the RIM while total plasma pressure is used to nudge the MHO solution towards the RAMSCB values. The impacts of the two way coupling are evaluated on three levels: the global magnetospheric level, focusing on the impact on the ionosphere and the shape of the magnetosphere, the regional level, examining the impact on the development of the ring current in terms of energy density, anisotropy, and plasma distribution, and the local level to compare the new results to in-situ measurements of magnetic and electric field and plasma. The results will also be compared to past simulations using the one way coupling and no coupling whatsoever. This work is the first to fully couple an anisotropic kinetic ring current code with a selfconsistently calculated magnetic field to a set of global models.« less

SCIDAC Center for simulation of wave particle interactions CompX participation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harvey, R.W.

Harnessing the energy that is released in fusion reactions would provide a safe and abundant source of power to meet the growing energy needs of the world population. The next step toward the development of fusion as a practical energy source is the construction of ITER, a device capable of producing and controlling the high performance plasma required for self-sustaining fusion reactions, or “burning” plasma. The input power required to drive the ITER plasma into the burning regime will be supplied primarily with a combination of external power from radio frequency waves in the ion cyclotron range of frequencies andmore » energetic ions from neutral beam injection sources, in addition to internally generated Ohmic heating from the induced plasma current that also serves to create the magnetic equilibrium for the discharge. The ITER project is a large multi-billion dollar international project in which the US participates. The success of the ITER project depends critically on the ability to create and maintain burning plasma conditions, it is absolutely necessary to have physics-based models that can accurately simulate the RF processes that affect the dynamical evolution of the ITER discharge. The Center for Simulation of WavePlasma Interactions (CSWPI), also known as RF-SciDAC, is a multi-institutional collaboration that has conducted ongoing research aimed at developing: (1) Coupled core-to-edge simulations that will lead to an increased understanding of parasitic losses of the applied RF power in the boundary plasma between the RF antenna and the core plasma; (2) Development of models for core interactions of RF waves with energetic electrons and ions (including fusion alpha particles and fast neutral beam ions) that include a more accurate representation of the particle dynamics in the combined equilibrium and wave fields; and (3) Development of improved algorithms that will take advantage of massively parallel computing platforms at the petascale level and beyond to achieve the needed physics, resolution, and/or statistics to address these issues. CompX provides computer codes and analysis for the calculation of the electron and ion distributions in velocity-space and plasma radius which are necessary for reliable calculations of power deposition and toroidal current drive due to combined radiofrequency and neutral beam at high injected powers. It has also contributed to ray tracing modeling of injected radiofrequency powers, and to coupling between full-wave radiofrequency wave models and the distribution function calculations. In the course of this research, the Fokker-Planck distribution function calculation was made substantially more realistic by inclusion of finite-width drift-orbit effects (FOW). FOW effects were also implemented in a calculation of the phase-space diffusion resulting from radiofrequency full-wave models. Average level of funding for CompX was approximately three man-months per year.« less

Coupled in silico platform: Computational fluid dynamics (CFD) and physiologically-based pharmacokinetic (PBPK) modelling.

PubMed

Vulović, Aleksandra; Šušteršič, Tijana; Cvijić, Sandra; Ibrić, Svetlana; Filipović, Nenad

2018-02-15

One of the critical components of the respiratory drug delivery is the manner in which the inhaled aerosol is deposited in respiratory tract compartments. Depending on formulation properties, device characteristics and breathing pattern, only a certain fraction of the dose will reach the target site in the lungs, while the rest of the drug will deposit in the inhalation device or in the mouth-throat region. The aim of this study was to link the Computational fluid dynamics (CFD) with physiologically-based pharmacokinetic (PBPK) modelling in order to predict aerolisolization of different dry powder formulations, and estimate concomitant in vivo deposition and absorption of amiloride hydrochloride. Drug physicochemical properties were experimentally determined and used as inputs for the CFD simulations of particle flow in the generated 3D geometric model of Aerolizer® dry powder inhaler (DPI). CFD simulations were used to simulate air flow through Aerolizer® inhaler and Discrete Phase Method (DPM) was used to simulate aerosol particles deposition within the fluid domain. The simulated values for the percent emitted dose were comparable to the values obtained using Andersen cascade impactor (ACI). However, CFD predictions indicated that aerosolized DPI have smaller particle size and narrower size distribution than assumed based on ACI measurements. Comparison with the literature in vivo data revealed that the constructed drug-specific PBPK model was able to capture amiloride absorption pattern following oral and inhalation administration. The PBPK simulation results, based on the CFD generated particle distribution data as input, illustrated the influence of formulation properties on the expected drug plasma concentration profiles. The model also predicted the influence of potential changes in physiological parameters on the extent of inhaled amiloride absorption. Overall, this study demonstrated the potential of the combined CFD-PBPK approach to model inhaled drug bioperformance, and suggested that CFD generated results might serve as input for the prediction of drug deposition pattern in vivo. Copyright © 2017 Elsevier B.V. All rights reserved.

Gas Gun Model and Comparison to Experimental Performance of Pipe Guns Operating with Light Propellant Gases and Large Cryogenic Pellets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Reed, J. R.; Carmichael, J. R.; Gebhart, T. E.

Injection of multiple large (~10 to 30 mm diameter) shattered pellets into ITER plasmas is presently part of the scheme planned to mitigate the deleterious effects of disruptions on the vessel components. To help in the design and optimize performance of the pellet injectors for this application, a model referred to as “the gas gun simulator” has been developed and benchmarked against experimental data. The computer code simulator is a Java program that models the gas-dynamics characteristics of a single-stage gas gun. Following a stepwise approach, the code utilizes a variety of input parameters to incrementally simulate and analyze themore » dynamics of the gun as the projectile is launched down the barrel. Using input data, the model can calculate gun performance based on physical characteristics, such as propellant-gas and fast-valve properties, barrel geometry, and pellet mass. Although the model is fundamentally generic, the present version is configured to accommodate cryogenic pellets composed of H2, D2, Ne, Ar, and mixtures of them and light propellant gases (H2, D2, and He). The pellets are solidified in situ in pipe guns that consist of stainless steel tubes and fast-acting valves that provide the propellant gas for pellet acceleration (to speeds ~200 to 700 m/s). The pellet speed is the key parameter in determining the response time of a shattered pellet system to a plasma disruption event. The calculated speeds from the code simulations of experiments were typically in excellent agreement with the measured values. With the gas gun simulator validated for many test shots and over a wide range of physical and operating parameters, it is a valuable tool for optimization of the injector design, including the fast valve design (orifice size and volume) for any operating pressure (~40 bar expected for the ITER application) and barrel length for any pellet size (mass, diameter, and length). Key design parameters and proposed values for the pellet injectors for the ITER disruption mitigation systems are discussed.« less

Tracking Solar Type II Bursts with Space Based Radio Interferometers

NASA Astrophysics Data System (ADS)

Hegedus, Alexander M.; Kasper, Justin C.; Manchester, Ward B.

2018-06-01

The Earth’s Ionosphere limits radio measurements on its surface, blocking out any radiation below 10 MHz. Valuable insight into many astrophysical processes could be gained by having a radio interferometer in space to image the low frequency window for the first time. One application is observing type II bursts tracking solar energetic particle acceleration in Coronal Mass Ejections (CMEs). In this work we create a simulated data processing pipeline for several space based radio interferometer (SBRI) concepts and evaluate their performance in the task of localizing these type II bursts.Traditional radio astronomy software is hard coded to assume an Earth based array. To circumvent this, we manually calculate the antenna separations and insert them along with the simulated visibilities into a CASA MS file for analysis. To create the realest possible virtual input data, we take a 2-temperature MHD simulation of a CME event, superimpose realistic radio emission models from the CME-driven shock front, and propagate the signal through simulated SBRIs. We consider both probabilistic emission models derived from plasma parameters correlated with type II bursts, and analytical emission models using plasma emission wave interaction theory.One proposed SBRI is the pathfinder mission SunRISE, a 6 CubeSat interferometer to circle the Earth in a GEO graveyard orbit. We test simulated trajectories of SunRISE and image what the array recovers, comparing it to the virtual input. An interferometer on the lunar surface would be a stable alternative that avoids noise sources that affect orbiting arrays, namely the phase noise from positional uncertainty and atmospheric 10s-100s kHz noise. Using Digital Elevation Models from laser altimeter data, we test different sets of locations on the lunar surface to find near optimal configurations for tracking type II bursts far from the sun. Custom software is used to model the response of different array configurations over the lunar year, combining ephemerides of the sun and moon to correlate the virtual data. We analyze the pros and cons of all approaches and offer recommendations for SRBIs that track type II bursts.

Gas Gun Model and Comparison to Experimental Performance of Pipe Guns Operating with Light Propellant Gases and Large Cryogenic Pellets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Combs, S. K.; Reed, J. R.; Lyttle, M. S.

2016-01-01

Injection of multiple large (~10 to 30 mm diameter) shattered pellets into ITER plasmas is presently part of the scheme planned to mitigate the deleterious effects of disruptions on the vessel components. To help in the design and optimize performance of the pellet injectors for this application, a model referred to as “the gas gun simulator” has been developed and benchmarked against experimental data. The computer code simulator is a Java program that models the gas-dynamics characteristics of a single-stage gas gun. Following a stepwise approach, the code utilizes a variety of input parameters to incrementally simulate and analyze themore » dynamics of the gun as the projectile is launched down the barrel. Using input data, the model can calculate gun performance based on physical characteristics, such as propellant-gas and fast-valve properties, barrel geometry, and pellet mass. Although the model is fundamentally generic, the present version is configured to accommodate cryogenic pellets composed of H2, D2, Ne, Ar, and mixtures of them and light propellant gases (H2, D2, and He). The pellets are solidified in situ in pipe guns that consist of stainless steel tubes and fast-acting valves that provide the propellant gas for pellet acceleration (to speeds ~200 to 700 m/s). The pellet speed is the key parameter in determining the response time of a shattered pellet system to a plasma disruption event. The calculated speeds from the code simulations of experiments were typically in excellent agreement with the measured values. With the gas gun simulator validated for many test shots and over a wide range of physical and operating parameters, it is a valuable tool for optimization of the injector design, including the fast valve design (orifice size and volume) for any operating pressure (~40 bar expected for the ITER application) and barrel length for any pellet size (mass, diameter, and length). Key design parameters and proposed values for the pellet injectors for the ITER disruption mitigation systems are discussed.« less

Analysis of LH Launcher Arrays (Like the ITER One) Using the TOPLHA Code

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maggiora, R.; Milanesio, D.; Vecchi, G.

2009-11-26

TOPLHA (Torino Polytechnic Lower Hybrid Antenna) code is an innovative tool for the 3D/1D simulation of Lower Hybrid (LH) antennas, i.e. accounting for realistic 3D waveguides geometry and for accurate 1D plasma models, and without restrictions on waveguide shape, including curvature. This tool provides a detailed performances prediction of any LH launcher, by computing the antenna scattering parameters, the current distribution, electric field maps and power spectra for any user-specified waveguide excitation. In addition, a fully parallelized and multi-cavity version of TOPLHA permits the analysis of large and complex waveguide arrays in a reasonable simulation time. A detailed analysis ofmore » the performances of the proposed ITER LH antenna geometry has been carried out, underlining the strong dependence of the antenna input parameters with respect to plasma conditions. A preliminary optimization of the antenna dimensions has also been accomplished. Electric current distribution on conductors, electric field distribution at the interface with plasma, and power spectra have been calculated as well. The analysis shows the strong capabilities of the TOPLHA code as a predictive tool and its usefulness to LH launcher arrays detailed design.« less

The pressure and energy balance of the cool corona over sunspots

NASA Technical Reports Server (NTRS)

Foukal, P. V.

1976-01-01

The 22 largest sunspots observed with the Skylab SO55 spectrometer are studied for a relation between their EUV radiation and their umbral size or magnetic classification. The ultimate goal is to determine why the coronal plasma is so cool over a sunspot and how this cool plasma manages to support itself against gravity. Based on the time behavior of the EUV emission, a steady-state model is developed for the pressure and energy balance of the cool coronal-plasma loops over the spots. Analysis of the temperature structure in a typical loop indicates that the loop is exceedingly well insulated from the outside corona, that its energy balance is determined purely by internal heating and cooling processes, and that a heat input of about 0.0001 erg/cu cm per sec is required along the full length of the loop. It is proposed that: (1) coronal material flows steadily across the field lines at the tops of the loops and falls downward along both sides under gravity; (2) the corona is heated by mechanical-energy transport across the very thin transition region immediately over network-cell interiors; and (3) strong magnetic fields tend to inhibit mechanical-energy dissipation in the corona.

Theory of ion Bernstein wave induced shear suppression of turbulence

NASA Astrophysics Data System (ADS)

Craddock, G. G.; Diamond, P. H.; Ono, M.; Biglari, H.

1994-06-01

The theory of radio frequency induced ion Bernstein wave- (IBW) driven shear flow in the edge is examined, with the goal of application of shear suppression of fluctuations. This work is motivated by the observed confinement improvement on IBW heated tokamaks [Phys. Fluids B 5, 241 (1993)], and by previous low-frequency work on RF-driven shear flows [Phys. Rev. Lett. 67, 1535 (1991)]. It is found that the poloidal shear flow is driven electrostatically by both Reynolds stress and a direct ion momentum source, analogous to the concepts of helicity injection and electron momentum input in current drive, respectively. Flow drive by the former does not necessarily require momentum input to the plasma to induce a shear flow. For IBW, the direct ion momentum can be represented by direct electron momentum input, and a charge separation induced stress that imparts little momentum to the plasma. The derived Er profile due to IBW predominantly points inward, with little possibility of direction change, unlike low-frequency Alfvénic RF drive. The profile scale is set by the edge density gradient and electron dissipation. Due to the electrostatic nature of ion Bernstein waves, the poloidal flow contribution dominates in Er. Finally, the necessary edge power absorbed for shear suppression on Princeton Beta Experiment-Modified (PBX-M) [9th Topical Conference on Radio Frequency Power in Plasmas, Charleston, SC, 1991 (American Institute of Physics, New York, 1991), p. 129] is estimated to be 100 kW distributed over 5 cm.

Influence of Magnetic Field Ripple on the Intrinsic Rotation of Tokamak Plasmas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nave, M. F. F.; Johnson, T.; Eriksson, L.-G.

Using the unique capability of JET to monotonically change the amplitude of the magnetic field ripple, without modifying other relevant equilibrium conditions, the effect of the ripple on the angular rotation frequency of the plasma column was investigated under the conditions of no external momentum input. The ripple amplitude was varied from 0.08% to 1.5% in Ohmic and ion-cyclotron radio-frequency (ICRF) heated plasmas. In both cases the ripple causes counterrotation, indicating a strong torque due to nonambipolar transport of thermal ions and in the case of ICRF also fast ions.

A combined spectroscopic and plasma chemical kinetic analysis of ionospheric samarium releases

NASA Astrophysics Data System (ADS)

Holmes, Jeffrey M.; Dressler, Rainer A.; Pedersen, Todd R.; Caton, Ronald G.; Miller, Daniel

2017-05-01

Two rocket-borne releases of samarium vapor in the upper atmosphere occurred in May 2013, as part of the Metal Oxide Space Clouds experiment. The releases were characterized by a combination of optical and RF diagnostic instruments located at the Roi-Namur launch site and surrounding islands and atolls. The evolution of the optical spectrum of the solar-illuminated cloud was recorded with a spectrograph covering a 400-800 nm spectral range. The spectra exhibit two distinct spectral regions centered at 496 and 636 nm within which the relative intensities change insignificantly. The ratio between the integrated intensities within these regions, however, changes with time, suggesting that they are associated with different species. With the help of an equilibrium plasma spectral model we attribute the region centered at 496 nm to neutral samarium atoms (Sm I radiance) and features peaking at 649 nm to a molecular species. No evidence for structure due to Sm+ (Sm II) is identified. The persistence of the Sm I radiance suggests a high dissociative recombination rate for the chemi-ionization product, SmO+. A one-dimensional plasma chemical kinetic model of the evolution of the density ratio NSmO/NSm(t) demonstrates that the molecular feature peaking at 649 nm can be attributed to SmO radiance. SmO+ radiance is not identified. By adjusting the Sm vapor mass of the chemical kinetic model input to match the evolution of the total electron density determined by ionosonde data, we conclude that less than 5% of the payload samarium was vaporized.

Sources of Sodium in the Lunar Exosphere: Modeling Using Ground-Based Observations of Sodium Emission and Spacecraft Data of the Plasma

NASA Technical Reports Server (NTRS)

Sarantos, Menelaos; Killen, Rosemary M.; Sharma, A. Surjalal; Slavin, James A.

2009-01-01

Observations of the equatorial lunar sodium emission are examined to quantify the effect of precipitating ions on source rates for the Moon's exospheric volatile species. Using a model of exospheric sodium transport under lunar gravity forces, the measured emission intensity is normalized to a constant lunar phase angle to minimize the effect of different viewing geometries. Daily averages of the solar Lyman alpha flux and ion flux are used as the input variables for photon-stimulated desorption (PSD) and ion sputtering, respectively, while impact vaporization due to the micrometeoritic influx is assumed constant. Additionally, a proxy term proportional to both the Lyman alpha and to the ion flux is introduced to assess the importance of ion-enhanced diffusion and/or chemical sputtering. The combination of particle transport and constrained regression models demonstrates that, assuming sputtering yields that are typical of protons incident on lunar soils, the primary effect of ion impact on the surface of the Moon is not direct sputtering but rather an enhancement of the PSD efficiency. It is inferred that the ion-induced effects must double the PSD efficiency for flux typical of the solar wind at 1 AU. The enhancement in relative efficiency of PSD due to the bombardment of the lunar surface by the plasma sheet ions during passages through the Earth's magnetotail is shown to be approximately two times higher than when it is due to solar wind ions. This leads to the conclusion that the priming of the surface is more efficiently carried out by the energetic plasma sheet ions.

Investigation of molten pool oscillation during GMAW-P process based on a 3D model

NASA Astrophysics Data System (ADS)

Wang, L. L.; Lu, F. G.; Cui, H. C.; Tang, X. H.

2014-11-01

In order to better reveal the oscillation mechanism of the pulsed gas metal arc welding (GMAW-P) process due to an alternately varied welding current, arc plasma and molten pool oscillation were simulated through a self-consistent three-dimensional model. Based on an experimental analysis of the dynamic variation of the arc plasma and molten pool captured by a high-speed camera, the model was validated by comparison of the measured and predicted results. The calculated results showed that arc pressure was the key factor causing the molten pool to oscillate. The variation in arc size and temperature from peak time to base time resulted in a great difference in the heat input and arc pressure acting on the molten pool. The surface deformation of the molten pool due to the varying degrees of arc pressure induced alternate displacement and backflow in the molten metal. The periodic iteration of deeper and shallower surface deformation, drain and backflow of molten metal caused the molten pool to oscillate at a certain frequency. In this condition, the arc pressure at the peak time is more than six times higher than that at the base time, and the maximum surface depression is 1.4 mm and 0.6 mm, respectively, for peak time and base time.

Streakline-based closed-loop control of a bluff body flow

NASA Astrophysics Data System (ADS)

Roca, Pablo; Cammilleri, Ada; Duriez, Thomas; Mathelin, Lionel; Artana, Guillermo

2014-04-01

A novel closed-loop control methodology is introduced to stabilize a cylinder wake flow based on images of streaklines. Passive scalar tracers are injected upstream the cylinder and their concentration is monitored downstream at certain image sectors of the wake. An AutoRegressive with eXogenous inputs mathematical model is built from these images and a Generalized Predictive Controller algorithm is used to compute the actuation required to stabilize the wake by adding momentum tangentially to the cylinder wall through plasma actuators. The methodology is new and has real-world applications. It is demonstrated on a numerical simulation and the provided results show that good performances are achieved.

Plasma Jet Interaction with Thomson Scattering Probe Laser

NASA Astrophysics Data System (ADS)

Byvank, Tom; Banasek, Jacob; Potter, William; Kusse, Bruce

2016-10-01

Thomson scattering systems can diagnose plasma temperatures and velocities. When probing a plasma jet with the Thomson scattering laser, we observe a laser-plasma interaction that inputs energy into the plasma jet. The absorbed energy causes a bubble of low density ( 5*1017 cm-2) in the jet (unperturbed 1018 cm-2). A pulsed power machine (1 MA peak current, 100 ns rise time) with a radial foil (15 μm thick Al) configuration generates the plasma jet. We compare the effects of using 10 J and 1 J laser energies, for which the 10 J laser is a larger perturbation. We discuss how the interaction affects the Thomson scattering temperature and velocity measurements. Work supported by National Nuclear Security Administration (NNSA) Stewardship Sciences Academic Programs under Department of Energy (DOE) Cooperative Agreement DE-NA0001836 and National Science Foundation (NSF) Grant PHY-1102471.

Characteristics of an Electron Cyclotron Resonance Plasma Source for the Production of Active Nitrogen Species in III-V Nitride Epitaxy

NASA Technical Reports Server (NTRS)

Meyyappan, Meyya; Arnold, James O. (Technical Monitor)

1997-01-01

A simple analysis is provided to determine the characteristics of an electron cyclotron resonance (ECR) plasma source for the generation of active nitrogen species in the molecular beam epitaxy of III-V nitrides. The effects of reactor geometry, pressure, power, and flow rate on the dissociation efficiency and ion flux are presented. Pulsing the input power is proposed to reduce the ion flux.

Investigation and control of the {{\\rm{O}}}_{3}- to {NO}-transition in a novel sub-atmospheric pressure dielectric barrier discharge

NASA Astrophysics Data System (ADS)

Bansemer, Robert; Schmidt-Bleker, Ansgar; van Rienen, Ursula; Weltmann, Klaus-Dieter

2017-06-01

A novel flow-driven dielectric barrier discharge concept is presented, which uses a Venturi pump to transfer plasma-generated reactive oxygen and nitrogen species from a sub-atmospheric pressure (200{--}600 {mbar}) discharge region to ambient pressure and can be operated with air. By adjusting the working pressure of the device, the plasma chemistry can be tuned continuously from an ozone ({{{O}}}3)-dominated mode to a nitrogen oxides ({{NO}}x)-only mode. The plasma source is characterized focusing on the mechanisms effecting this mode change. The composition of the device’s output gas was determined using Fourier-transform infrared spectroscopy. The results are correlated to measurements of discharge chamber pressure and temperature as well as of input power. It is found that the mode-change temperature can be controlled by the discharge chamber pressure. The source concept is capable of generating an {{NO}}x-dominated plasma chemistry at gas temperatures distinctly below 400 {{K}}. Through mixing of the processed gas stream with a second flow of pressurized air required for the operation of the Venturi pump, the resulting product gas stream remains close to room temperature. A reduced zero-dimensional reaction kinetics model with only seven reactions is capable of describing the observed pressure- and temperature-dependence of the {{{O}}}3 to {{NO}}x mode-change.

Endogenous Magnetic Reconnection in Solar Coronal Loops

NASA Astrophysics Data System (ADS)

Asgari-Targhi, M.; Coppi, B.; Basu, B.; Fletcher, A.; Golub, L.

2017-12-01

We propose that a magneto-thermal reconnection process occurring in coronal loops be the source of the heating of the Solar Corona [1]. In the adopted model, magnetic reconnection is associated with electron temperature gradients, anisotropic electron temperature fluctuations and plasma current density gradients [2]. The input parameters for our theoretical model are derived from the most recent observations of the Solar Corona. In addition, the relevant (endogenous) collective modes can produce high energy particle populations. An endogenous reconnection process is defined as being driven by factors internal to the region where reconnection takes place. *Sponsored in part by the U.S. D.O.E. and the Kavli Foundation* [1] Beafume, P., Coppi, B. and Golub, L., (1992) Ap. J. 393, 396. [2] Coppi, B. and Basu, B. (2017) MIT-LNS Report HEP 17/01.

Slit shaped microwave induced atmospheric pressure plasma based on a parallel plate transmission line resonator

NASA Astrophysics Data System (ADS)

Kang, S. K.; Seo, Y. S.; Lee, H. Wk; Aman-ur-Rehman; Kim, G. C.; Lee, J. K.

2011-11-01

A new type of microwave-excited atmospheric pressure plasma source, based on the principle of parallel plate transmission line resonator, is developed for the treatment of large areas in biomedical applications such as skin treatment and wound healing. A stable plasma of 20 mm width is sustained by a small microwave power source operated at a frequency of 700 MHz and a gas flow rate of 0.9 slm. Plasma impedance and plasma density of this plasma source are estimated by fitting the calculated reflection coefficient to the measured one. The estimated plasma impedance shows a decreasing trend while estimated plasma density shows an increasing trend with the increase in the input power. Plasma uniformity is confirmed by temperature and optical emission distribution measurements. Plasma temperature is sustained at less than 40 °C and abundant amounts of reactive species, which are important agents for bacteria inactivation, are detected over the entire plasma region. Large area treatment ability of this newly developed device is verified through bacteria inactivation experiment using E. coli. Sterilization experiment shows a large bacterial killing mark of 25 mm for a plasma treatment time of 10 s.

The two-way relationship between ionospheric outflow and the ring current

DOE Office of Scientific and Technical Information (OSTI.GOV)

Welling, Daniel T.; Jordanova, Vania Koleva; Glocer, Alex

It is now well established that the ionosphere, because it acts as a significant source of plasma, plays a critical role in ring current dynamics. However, because the ring current deposits energy into the ionosphere, the inverse may also be true: the ring current can play a critical role in the dynamics of ionospheric outflow. This study uses a set of coupled, first-principles-based numerical models to test the dependence of ionospheric outflow on ring current-driven region 2 field-aligned currents (FACs). A moderate magnetospheric storm event is modeled with the Space Weather Modeling Framework using a global MHD code (Block Adaptivemore » Tree Solar wind Roe-type Upwind Scheme, BATS-R-US), a polar wind model (Polar Wind Outflow Model), and a bounce-averaged kinetic ring current model (ring current atmosphere interaction model with self-consistent magnetic field, RAM-SCB). Initially, each code is two-way coupled to all others except for RAM-SCB, which receives inputs from the other models but is not allowed to feed back pressure into the MHD model. The simulation is repeated with pressure coupling activated, which drives strong pressure gradients and region 2 FACs in BATS-R-US. It is found that the region 2 FACs increase heavy ion outflow by up to 6 times over the non-coupled results. The additional outflow further energizes the ring current, establishing an ionosphere-magnetosphere mass feedback loop. This study further demonstrates that ionospheric outflow is not merely a plasma source for the magnetosphere but an integral part in the nonlinear ionosphere-magnetosphere-ring current system.« less

The two-way relationship between ionospheric outflow and the ring current

DOE PAGES

Welling, Daniel T.; Jordanova, Vania Koleva; Glocer, Alex; ...

2015-06-01

It is now well established that the ionosphere, because it acts as a significant source of plasma, plays a critical role in ring current dynamics. However, because the ring current deposits energy into the ionosphere, the inverse may also be true: the ring current can play a critical role in the dynamics of ionospheric outflow. This study uses a set of coupled, first-principles-based numerical models to test the dependence of ionospheric outflow on ring current-driven region 2 field-aligned currents (FACs). A moderate magnetospheric storm event is modeled with the Space Weather Modeling Framework using a global MHD code (Block Adaptivemore » Tree Solar wind Roe-type Upwind Scheme, BATS-R-US), a polar wind model (Polar Wind Outflow Model), and a bounce-averaged kinetic ring current model (ring current atmosphere interaction model with self-consistent magnetic field, RAM-SCB). Initially, each code is two-way coupled to all others except for RAM-SCB, which receives inputs from the other models but is not allowed to feed back pressure into the MHD model. The simulation is repeated with pressure coupling activated, which drives strong pressure gradients and region 2 FACs in BATS-R-US. It is found that the region 2 FACs increase heavy ion outflow by up to 6 times over the non-coupled results. The additional outflow further energizes the ring current, establishing an ionosphere-magnetosphere mass feedback loop. This study further demonstrates that ionospheric outflow is not merely a plasma source for the magnetosphere but an integral part in the nonlinear ionosphere-magnetosphere-ring current system.« less

Programming of a flexible computer simulation to visualize pharmacokinetic-pharmacodynamic models.

PubMed

Lötsch, J; Kobal, G; Geisslinger, G

2004-01-01

Teaching pharmacokinetic-pharmacodynamic (PK/PD) models can be made more effective using computer simulations. We propose the programming of educational PK or PK/PD computer simulations as an alternative to the use of pre-built simulation software. This approach has the advantage of adaptability to non-standard or complicated PK or PK/PD models. Simplicity of the programming procedure was achieved by selecting the LabVIEW programming environment. An intuitive user interface to visualize the time courses of drug concentrations or effects can be obtained with pre-built elements. The environment uses a wiring analogy that resembles electrical circuit diagrams rather than abstract programming code. The goal of high interactivity of the simulation was attained by allowing the program to run in continuously repeating loops. This makes the program behave flexibly to the user input. The programming is described with the aid of a 2-compartment PK simulation. Examples of more sophisticated simulation programs are also given where the PK/PD simulation shows drug input, concentrations in plasma, and at effect site and the effects themselves as a function of time. A multi-compartmental model of morphine, including metabolite kinetics and effects is also included. The programs are available for download from the World Wide Web at http:// www. klinik.uni-frankfurt.de/zpharm/klin/ PKPDsimulation/content.html. For pharmacokineticists who only program occasionally, there is the possibility of building the computer simulation, together with the flexible interactive simulation algorithm for clinical pharmacological teaching in the field of PK/PD models.

Ferromagnetic core valve gives rapid action on minimum energy

NASA Technical Reports Server (NTRS)

Larson, A. V.; Tinkham, J. P.

1967-01-01

Miniature solenoid valve controls propellant flow during tests on a coaxial plasma accelerator. It uses an advanced ferromagnetic core design which meets all the rapid-acting requirements with a minimum of input energy.

Modeling the capillary discharge of an electrothermal (ET) launcher

NASA Astrophysics Data System (ADS)

Least, Travis

Over the past few decades, different branches of the US Department of Defense (DoD) have invested at improving the field ability of electromagnetic launchers. One such focus has been on achieving hypervelocity launch velocities in excess of 7 km/s for direct launch to space applications [1]. It has been shown that pre-injection is required for this to be achieved. One method of pre-injection which has promise involves using an electro-thermal (ET) due to its ability to achieve the desired velocities with a minimal amount of hot plasma injected into the launcher behind the projectile. Despite the demonstration of pre-injection using this method, polymer ablation is not very well known and this makes it challenging to predict how the system will behave for a given input of electrical power. In this work, the rate of ablation has been studied and predicted using different models to generate the best possible characteristic curve. [1] - Wetz, David A., Francis Stefani, Jerald V. Parker, and Ian R. McNab. "Advancements in the Development of a Plasma-Driven Electromagnetic Launcher." IEEE TRANSACTIONS ON MAGNETICS 45.1 (2009): 495--500. IEEE Xplore. Web. 18 Aug. 2012.

Atmospheric-pressure plasma activation and surface characterization on polyethylene membrane separator

NASA Astrophysics Data System (ADS)

Tseng, Yu-Chien; Li, Hsiao-Ling; Huang, Chun

2017-01-01

The surface hydrophilic activation of a polyethylene membrane separator was achieved using an atmospheric-pressure plasma jet. The surface of the atmospheric-pressure-plasma-treated membrane separator was found to be highly hydrophilic realized by adjusting the plasma power input. The variations in membrane separator chemical structure were confirmed by Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy. Chemical analysis showed newly formed carbonyl-containing groups and high surface concentrations of oxygen-containing species on the atmospheric-pressure-plasma-treated polymeric separator surface. It also showed that surface hydrophilicity primarily increased from the polar component after atmospheric-pressure plasma treatment. The surface and pore structures of the polyethylene membrane separator were examined by scanning electron microscopy, revealing a slight alteration in the pore structure. As a result of the incorporation of polar functionalities by atmospheric-pressure plasma activation, the electrolyte uptake and electrochemical impedance of the atmospheric-pressure-plasma-treated membrane separator improved. The investigational results show that the separator surface can be controlled by atmospheric-pressure plasma surface treatment to tailor the hydrophilicity and enhance the electrochemical performance of lithium ion batteries.

Radio-frequency power-assisted performance improvement of a magnetohydrodynamic power generator

NASA Astrophysics Data System (ADS)

Murakami, Tomoyuki; Okuno, Yoshihiro; Yamasaki, Hiroyuki

2005-12-01

We describe a radio-frequency (rf) electromagnetic-field-assisted magnetohydrodynamic power generation experiment, where an inductively coupled rf field (13.56MHz, 5.2kW) is continuously supplied to the disk generator. The rf power assists the precise plasma ignition, by which the otherwise irregular plasma behavior was stabilized. The rf heating suppresses the ionization instability in the plasma behavior and homogenizes the nonuniformity of the plasma structures. The power-generating performance is significantly improved with the aid of the rf power under wide seeding conditions: insufficient, optimum, and excessive seed fractions. The increment of the enthalpy extraction ratio of around 2% is significantly greater than the fraction of the net rf power, that is, 0.16%, to the thermal input.

A non-LTE analysis of high energy density Kr plasmas on Z and NIF

DOE PAGES

Dasgupta, A.; Clark, R. W.; Ouart, N.; ...

2016-10-20

We report that multi-keV X-ray radiation sources have a wide range of applications, from biomedical studies and research on thermonuclear fusion to materials science and astrophysics. The refurbished Z pulsed power machine at the Sandia National Laboratories produces intense multi-keV X-rays from argon Z-pinches, but for a krypton Z-pinch, the yield decreases much faster with atomic number Z A than similar sources on the National Ignition Facility (NIF) laser at the Lawrence Livermore National Laboratory. To investigate whether fundamental energy deposition differences between pulsed power and lasers could account for the yield differences, we consider the Kr plasma on themore » two machines. The analysis assumes the plasma not in local thermodynamic equilibrium, with a detailed coupling between the hydrodynamics, the radiation field, and the ionization physics. While for the plasma parameters of interest the details of krypton’s M-shell are not crucial, both the L-shell and the K-shell must be modeled in reasonable detail, including the state-specific dielectronic recombination processes that significantly affect Kr’s ionization balance and the resulting X-ray spectrum. We present a detailed description of the atomic model, provide synthetic K- and L-shell spectra, and compare these with the available experimental data from the Z-machine and from NIF to show that the K-shell yield behavior versus Z A is indeed related to the energy input characteristics. In conclusion, this work aims at understanding the probable causes that might explain the differences in the X-ray conversion efficiencies of several radiation sources on Z and« less

A non-LTE analysis of high energy density Kr plasmas on Z and NIF

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dasgupta, A.; Clark, R. W.; Ouart, N.

We report that multi-keV X-ray radiation sources have a wide range of applications, from biomedical studies and research on thermonuclear fusion to materials science and astrophysics. The refurbished Z pulsed power machine at the Sandia National Laboratories produces intense multi-keV X-rays from argon Z-pinches, but for a krypton Z-pinch, the yield decreases much faster with atomic number Z A than similar sources on the National Ignition Facility (NIF) laser at the Lawrence Livermore National Laboratory. To investigate whether fundamental energy deposition differences between pulsed power and lasers could account for the yield differences, we consider the Kr plasma on themore » two machines. The analysis assumes the plasma not in local thermodynamic equilibrium, with a detailed coupling between the hydrodynamics, the radiation field, and the ionization physics. While for the plasma parameters of interest the details of krypton’s M-shell are not crucial, both the L-shell and the K-shell must be modeled in reasonable detail, including the state-specific dielectronic recombination processes that significantly affect Kr’s ionization balance and the resulting X-ray spectrum. We present a detailed description of the atomic model, provide synthetic K- and L-shell spectra, and compare these with the available experimental data from the Z-machine and from NIF to show that the K-shell yield behavior versus Z A is indeed related to the energy input characteristics. In conclusion, this work aims at understanding the probable causes that might explain the differences in the X-ray conversion efficiencies of several radiation sources on Z and« less

Density and beta limits in the Madison Symmetric Torus Reversed-Field Pinch

NASA Astrophysics Data System (ADS)

Caspary, Kyle Jonathan

Operational limits and the underlying physics are explored on the Madison Symmetric Torus (MST) Reversed-Field Pinch (RFP) using deuterium pellet fueling. The injection of a fast pellet provides a large source of fuel in the plasma edge upon impact with the vessel wall, capable of triggering density limit terminations for the full range of plasma current, up to 600 kA. As the pellet size and plasma density increase, approaching the empirical Greenwald limit, plasma degradation is observed in the form of current decay, increased magnetic activity in the edge and core, increased radiation and plasma cooling. The complete termination of the plasma is consistent with the Greenwald limit; however, a slightly smaller maximum density is observed in discharges without toroidal field reversal. The plasma beta is the ratio of the plasma pressure to the confining magnetic pressure. Beta limits are known to constrain other magnetic confinement devices, but no beta limit has yet been established on the RFP. On MST, the highest beta values are obtained in improved confinement discharges with pellet fueling. By using pellet injection to scan the plasma density during PPCD, we also achieve a scan of Ohmic input power due to the increase in plasma resistivity. We observe a factor of 3 or more increase in Ohmic power as we increase the density from 1*1019 to 3*10 19 m-3. Despite this increased Ohmic power, the electron contribution to beta is constant, suggesting a confinement limited beta for the RFP. The electrons and ions are classically well coupled in these cold, dense pellet fueled plasmas, so the increase in total beta at higher density is primarily due to the increased ion contribution. The interaction of pellet fueling and NBI heating is explored. Modeling of MST's neutral heating beam suggests an optimal density for beam power deposition of 2-3*1019 m-3. Low current, NBI heated discharges show evidence of an increased electron beta in this density range. Additionally, the fast ion population can enhance ablation as well as cause pellet deflection. Other exploratory experiments with the pellet injection system explore additional injection scenarios and expand the injector capabilities.

Magnetically Controlled Upper Ionosphere of Mars

NASA Astrophysics Data System (ADS)

Majeed, T.; Al Aryani, O.; Al Mutawa, S.; Bougher, S. W.; Haider, S. A.

2017-12-01

The electron density (Ne) profiles measured by the Mars Express spacecraft over regions of strong crustal magnetic fields have shown anomalous characteristics of the topside plasma distribution with variable scale heights. One of such Ne profiles is located at 82oS and 180oE whose topside ionosphere is extended up to an altitude of 700 km. The crustal magnetic field at this southern site is nearly vertical and open to the access of solar wind plasma through magnetic reconnection with the interplanetary magnetic field. This can lead to the acceleration of electrons and ions during the daytime ionosphere. The downward accelerated electrons with energies >200 eV can penetrate deep into the Martian upper ionosphere along vertical magnetic field lines and cause heating, excitation and ionization of the background atmosphere. The upward acceleration of ions resulting from energy input by precipitating electrons can lead to enhance ion escape rate and modify scale heights of the topside ionosphere. We have developed a 1-D chemical diffusive model from 100 km to 400 km to interpret the Martian ionospheric structure at 82oS latitude. The primary source of ionization in the model is due to solar EUV radiation. An extra ionization source due to precipitating electrons of 0.25 keV, peaking near an altitude of 145 km is added in the model to reasonably reproduce the measured ionospheric structure below an altitude of 180 km. The behavior of the topside ionosphere can be interpreted by the vertical plasma transport caused by precipitating electrons. The vertical transport of plasma in our model is simulated by vertical ion velocities, whose values can be interpreted as drift velocities along magnetic field lines. We find that the variation of the topside Ne scale heights is sensitive to the magnitudes of upward and downward drifts with an imposed outward flux boundary condition at the top of the model. The model requires an upward flux of more than 107 ions cm-2 s-1 for both O2+ and O+, and drift speeds of 200 m/s to interpret the measured topside ionospheric structure for altitudes >180 km. The magnitudes of outward ion fluxes and drift velocities are compared with those simulated by existing models. The model results will be presented in comparison with the measured electron density profile. This work is supported by MBRSC, Dubai, UAE.

Electromagnetic radiation from beam-plasma instabilities

NASA Technical Reports Server (NTRS)

Pritchett, P. L.; Dawson, J. M.

1983-01-01

A computer simulation is developed for the generation of electromagnetic radiation in an electron beam-plasma interaction. The plasma is treated as a two-dimensional finite system, and effects of a continuous nonrelativistic beam input are accounted for. Three momentum and three field components are included in the simulation, and an external magnetic field is excluded. EM radiation generation is possible through interaction among Langmuir oscillations, ion-acoustic waves, and the electromagnetic wave, producing radiation perpendicular to the beam. The radiation is located near the plasma frequency, and polarized with the E component parallel to the beam. The scattering of Langmuir waves caused by ion-acoustic fluctuations generates the radiation. Comparison with laboratory data for the three-wave interactions shows good agreement in terms of the radiation levels produced, which are small relative to the plasma thermal energy.

Improvement of In-Flight Alumina Spheroidization Process Using a Small Power Argon DC-RF Hybrid Plasma Flow System by Helium Mixture

NASA Astrophysics Data System (ADS)

Takana, Hidemasa; Jang, Juyong; Igawa, Junji; Nakajima, Tomoki; Solonenko, Oleg P.; Nishiyama, Hideya

2011-03-01

For the further improvement of in-flight alumina spheroidization process with a low-power direct-current radiofrequency (DC-RF) hybrid plasma flow system, the effect of a small amount of helium gas mixture in argon main gas and also the effect of increasing DC nozzle diameter on powder spheroidization ratio have been experimentally clarified with correlating helium gas mixture percentage, plasma enthalpy, powder in-flight velocity, and temperature. The alumina spheroidization ratio increases by helium gas mixture as a result of enhancement of plasma enthalpy. The highest spheroidization ratio is obtained by 4% mixture of helium in central gas with enlarging nozzle diameter from 3 to 4 mm, even under the constant low input electric power given to a DC-RF hybrid plasma flow system.

Using Electrolyte Free Water Balance to Rationalize and Treat Dysnatremias.

PubMed

Shah, Sanjeev R; Bhave, Gautam

2018-01-01

Dysnatremias or abnormalities in plasma [Na + ] are often termed disorders of water balance, an unclear physiologic concept often confused with changes in total fluid balance. However, most clinicians clearly recognize that hypertonic or hypotonic gains or losses alter plasma [Na + ], while isotonic changes do not modify plasma [Na + ]. This concept can be conceptualized as the electrolyte free water balance (EFWB), which defines the non-isotonic components of inputs and outputs to determine their effect on plasma [Na + ]. EFWB is mathematically proportional to the rate of change in plasma [Na + ] (dP Na /dt) and, therefore, is actively regulated to zero so that plasma [Na + ] remains stable at its homeostatic set point. Dysnatremias are, therefore, disorders of EFWB and the relationship between EFWB and dP Na /dt provides a rationale for therapeutic strategies incorporating mass and volume balance. Herein, we leverage dP Na /dt as a desired rate of correction of plasma [Na + ] to define a stepwise approach for the treatment of dysnatremias.

Using Electrolyte Free Water Balance to Rationalize and Treat Dysnatremias

PubMed Central

Shah, Sanjeev R.; Bhave, Gautam

2018-01-01

Dysnatremias or abnormalities in plasma [Na+] are often termed disorders of water balance, an unclear physiologic concept often confused with changes in total fluid balance. However, most clinicians clearly recognize that hypertonic or hypotonic gains or losses alter plasma [Na+], while isotonic changes do not modify plasma [Na+]. This concept can be conceptualized as the electrolyte free water balance (EFWB), which defines the non-isotonic components of inputs and outputs to determine their effect on plasma [Na+]. EFWB is mathematically proportional to the rate of change in plasma [Na+] (dPNa/dt) and, therefore, is actively regulated to zero so that plasma [Na+] remains stable at its homeostatic set point. Dysnatremias are, therefore, disorders of EFWB and the relationship between EFWB and dPNa/dt provides a rationale for therapeutic strategies incorporating mass and volume balance. Herein, we leverage dPNa/dt as a desired rate of correction of plasma [Na+] to define a stepwise approach for the treatment of dysnatremias. PMID:29740578

High frequency plasma generator for ion thrusters

NASA Technical Reports Server (NTRS)

Goede, H.; Divergilio, W. F.; Fosnight, V. V.; Komatsu, G.

1984-01-01

The results of a program to experimentally develop two new types of plasma generators for 30 cm electrostatic argon ion thrusters are presented. The two plasma generating methods selected for this study were by radio frequency induction (RFI), operating at an input power frequency of 1 MHz, and by electron cyclotron heating (ECH) at an operating frequency of 5.0 GHz. Both of these generators utilize multiline cusp permanent magnet configurations for plasma confinement and beam profile optimization. The program goals were to develop a plasma generator possessing the characteristics of high electrical efficiency (low eV/ion) and simplicity of operation while maintaining the reliability and durability of the conventional hollow cathode plasma sources. The RFI plasma generator has achieved minimum discharge losses of 120 eV/ion while the ECH generator has obtained 145 eV/ion, assuming a 90% ion optical transparency of the electrostatic acceleration system. Details of experimental tests with a variety of magnet configurations are presented.

Online plasma calculator

NASA Astrophysics Data System (ADS)

Wisniewski, H.; Gourdain, P.-A.

2017-10-01

APOLLO is an online, Linux based plasma calculator. Users can input variables that correspond to their specific plasma, such as ion and electron densities, temperatures, and external magnetic fields. The system is based on a webserver where a FastCGI protocol computes key plasma parameters including frequencies, lengths, velocities, and dimensionless numbers. FastCGI was chosen to overcome security problems caused by JAVA-based plugins. The FastCGI also speeds up calculations over PHP based systems. APOLLO is built upon the WT library, which turns any web browser into a versatile, fast graphic user interface. All values with units are expressed in SI units except temperature, which is in electron-volts. SI units were chosen over cgs units because of the gradual shift to using SI units within the plasma community. APOLLO is intended to be a fast calculator that also provides the user with the proper equations used to calculate the plasma parameters. This system is intended to be used by undergraduates taking plasma courses as well as graduate students and researchers who need a quick reference calculation.

Mechanism of Growth Enhancement of Plants Induced by Active Species in Plasmas

NASA Astrophysics Data System (ADS)

Watanabe, Satoshi; Ono, Reoto; Hayashi, Nobuya

2015-09-01

Plant growth enhances when seeds are irradiated by plasma. However the mechanism of the growth enhancement by plasma has not been clarified. In this study, growth enhancement of plants using various active species and variation of plant cells are investigated. RF plasma is generated under conditions where pressure is 60 Pa and input electrical power is 60 W. Irradiation period varies from 0 (control) to 75 min. Air plasma shows maximum growth of plants with irradiation period of 60 min on the other hand, oxygen plasma shows the maximum growth with irradiation period of 15 min. From change of gaseous species and pressure dependence, growth enhancing factor is expected to be active oxygen species produced in plasma. According to gene expression analysis of Arabidopsis, there are two speculated mechanism of plant growth enhancement. The first is acceleration of cell cycle by gene expressions of photosynthesis and glycolytic pathway, and the second is increase of cell size via plant hormone production.

A fluid modeling perspective on the tokamak power scrape-off width using SOLPS-ITER

NASA Astrophysics Data System (ADS)

Meier, Eric

2016-10-01

SOLPS-ITER, a 2D fluid code, is used to conduct the first fluid modeling study of the physics behind the power scrape-off width (λq). When drift physics are activated in the code, λq is insensitive to changes in toroidal magnetic field (Bt), as predicted by the 0D heuristic drift (HD) model developed by Goldston. Using the HD model, which quantitatively agrees with regression analysis of a multi-tokamak database, λq in ITER is projected to be 1 mm instead of the previously assumed 4 mm, magnifying the challenge of maintaining the peak divertor target heat flux below the technological limit. These simulations, which use DIII-D H-mode experimental conditions as input, and reproduce the observed high-recycling, attached outer target plasma, allow insights into the scrape-off layer (SOL) physics that set λq. Independence of λq with respect to Bt suggests that SOLPS-ITER captures basic HD physics: the effect of Bt on the particle dwell time ( Bt) cancels with the effect on drift speed ( 1 /Bt), fixing the SOL plasma density width, and dictating λq. Scaling with plasma current (Ip), however, is much weaker than the roughly 1 /Ip dependence predicted by the HD model. Simulated net cross-separatrix particle flux due to magnetic drifts exceeds the anomalous particle transport, and a Pfirsch-Schluter-like SOL flow pattern is established. Up-down ion pressure asymmetry enables the net magnetic drift flux. Drifts establish in-out temperature asymmetry, and an associated thermoelectric current carries significant heat flux to the outer target. The density fall-off length in the SOL is similar to the electron temperature fall-off length, as observed experimentally. Finally, opportunities and challenges foreseen in ongoing work to extrapolate SOLPS-ITER and the HD model to ITER and future machines will be discussed. Supported by U.S. Department of Energy Contract DESC0010434.

Data Assimilation Results from PLASMON

NASA Astrophysics Data System (ADS)

Jorgensen, A. M.; Lichtenberger, J.; Duffy, J.; Friedel, R. H.; Clilverd, M.; Heilig, B.; Vellante, M.; Manninen, J. K.; Raita, T.; Rodger, C. J.; Collier, A.; Reda, J.; Holzworth, R. H.; Ober, D. M.; Boudouridis, A.; Zesta, E.; Chi, P. J.

2013-12-01

VLF and magnetometer observations can be used to remotely sense the plasmasphere. VLF whistler waves can be used to measure the electron density and magnetic Field Line Resonance (FLR) measurements can be used to measure the mass density. In principle it is then possible to remotely map the plasmasphere with a network of ground-based stations which are also less expensive and more permanent than satellites. The PLASMON project, funded by the EU FP-7 program, is in the process of doing just this. A large number of ground-based observations will be input into a data assimilative framework which models the plasmasphere structure and dynamics. The data assimilation framework combines the Ensemble Kalman Filter with the Dynamic Global Core Plasma Model. In this presentation we will describe the plasmasphere model, the data assimilation approach that we have taken, PLASMON data and data assimilation results for specific events.

Energy dynamics in a simulation of LAPD turbulence

NASA Astrophysics Data System (ADS)

Friedman, Brett

2012-10-01

It is often assumed that linear instabilities maintain turbulence in plasmas and some fluids, but this is not always the case. It is well known that many fluids display subcritical turbulence at a Reynolds number well below the threashold of linear instability. Certain plasma models such as drift waves in a sheared slab also exhibit subcritical turbulence [1]. In other instances such as drift-ballooning turbulence in tokamak edge plasmas, linear instabilities exist in a system, but they become subdominant to more robust nonlinear mechanisms that sustain a turbulent state [2, 3]. In our simulation of LAPD turbulence, which was previously analyzed in [4], we diagnose the results using an energy dynamics analysis [5]. This allows us to track energy input into turbulent fluctuations and energy dissipation out of them. We also track conservative energy transfer between different energy types (e.g. from potential to kinetic energy) and between different Fourier waves of the system. The result is that a nonlinear instability drives and maintains the turbulence in the steady state saturated phase of the simulation. While a linear restistive drift wave instability resides in the system, the nonlinear drift wave instability dominates when the fluctuation amplitude becomes large enough. The nonlinear instability is identified by its energy growth rate spectrum, which varies significantly from the linear growth rate spectrum. The main differences are the presence of positive growth rates when k|| = 0 and negative growth rates for nonzero k||, which is opposite that of the linear growth rate spectrum.[4pt] [1] B. D. Scott, Phys. Rev. Lett., 65, 3289 (1990).[0pt] [2] A. Zeiler et al, Phys. Plasmas, 3, 2951 (1996).[0pt] [3] B. D. Scott, Phys. Plasmas, 12, 062314 (2005).[0pt] [4] P. Popovich et al, Phys. Plasmas, 17, 122312 (2010).[0pt] [5] [physics.plasm-ph].

Numerical simulation of the plasma thermal disturbances during ionospheric modification experiments at the SURA heating facility

NASA Astrophysics Data System (ADS)

Belov, Alexey; Huba, J. D.

indent=1cm We present the results of numerical simulation of the near-Earth plasma disturbances produced by resonant heating of the ionospheric F-region by high-power HF radio emission from the SURA facility. The computational model is based on the modified version of the SAMI2 code (release 1.00). The model input parameters are appropriated to the conditions of the SURA-DEMETER experiment. In this work, we study the spatial structure and temporal characteristics of stimulated large-scale disturbances of the electron number density and temperature. It is shown that the stimulated disturbances are observed throughout the ionosphere. Disturbances are recorded both in the region below the pump wave reflection level and in the outer ionosphere (up to 3000 km). At the DEMETER altitude, an increase in the ion number density is stipulated by the oxygen ions O (+) , whereas the number density of lighter H (+) ions decreases. A typical time of the formation of large-scale plasma density disturbances in the outer ionosphere is 2-3 min. After the heater is turned off, the disturbances relaxation time is approximately 30 min. The simulation results are important for planning future promising experiments on the formation of ionospheric artificial density ducts. This work was supported by the Russian Foundation for Basic Research (project No. 12-02-00747-a), and the Government of the Russian Federation (contract No. 14.B25.31.0008).

Toroidal modeling of the n = 1 intrinsic error field correction experiments in EAST

NASA Astrophysics Data System (ADS)

Yang, Xu; Liu, Yueqiang; Sun, Youwen; Wang, Huihui; Gu, Shuai; Jia, Manni; Li, Li; Liu, Yue; Wang, Zhirui; Zhou, Lina

2018-05-01

The m/n = 2/1 resonant vacuum error field (EF) in the EAST tokamak experiments, inferred from the compass coil current amplitude and phase scan for mode locking, was found to depend on the parity between the upper and lower rows of the EF correction (EFC) coils (Wang et al 2016 Nucl. Fusion 56 066011). Here m and n are the poloidal and toroidal harmonic numbers in a torus, respectively. This experimental observation implies that the compass scan results cannot be simply interpreted as reflecting the true intrinsic EF. This work aims at understanding this puzzle, based on toroidal modeling of the EFC plasma discharge in EAST using the MARS-F code (Liu et al 2000 Phys. Plasmas 7 3681). By varying the amplitude and phase of the assumed n = 1 intrinsic vacuum EF with different poloidal spectra, and by computing the plasma response to the assumed EF, the compass scan predicted 2/1 EF, based on minimizing the computed resonant electromagnetic torque, can be made to match well with that of the EFC experiments using both even and odd parity coils. Moreover, the compass scan predicted vacuum EFs are found to be significantly differing from the true intrinsic EF used as input to the MARS-F code. While the puzzling result remains to be fully resolved, the results from this study offer an improved understanding of the EFC experiments and the compass scan technique for determining the intrinsic resonant EF.

The Quest for Value-Added Products from Carbon Dioxide and Water in a Dielectric Barrier Discharge: A Chemical Kinetics Study.

PubMed

Snoeckx, Ramses; Ozkan, Alp; Reniers, Francois; Bogaerts, Annemie

2017-01-20

Recycling of carbon dioxide by its conversion into value-added products has gained significant interest owing to the role it can play for use in an anthropogenic carbon cycle. The combined conversion with H 2 O could even mimic the natural photosynthesis process. An interesting gas conversion technique currently being considered in the field of CO 2 conversion is plasma technology. To investigate whether it is also promising for this combined conversion, we performed a series of experiments and developed a chemical kinetics plasma chemistry model for a deeper understanding of the process. The main products formed were the syngas components CO and H 2 , as well as O 2 and H 2 O 2 , whereas methanol formation was only observed in the parts-per-billion to parts-per-million range. The syngas ratio, on the other hand, could easily be controlled by varying both the water content and/or energy input. On the basis of the model, which was validated with experimental results, a chemical kinetics analysis was performed, which allowed the construction and investigation of the different pathways leading to the observed experimental results and which helped to clarify these results. This approach allowed us to evaluate this technology on the basis of its underlying chemistry and to propose solutions on how to further improve the formation of value-added products by using plasma technology. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Comparison of electrical and optical characteristics in gas-phase and gas-liquid phase discharges

DOE Office of Scientific and Technical Information (OSTI.GOV)

Qazi, H. I. A.; Li, He-Ping, E-mail: liheping@tsinghua.edu.cn; Zhang, Xiao-Fei

This paper presents an AC-excited argon discharge generated using a gas-liquid (two-phase) hybrid plasma reactor, which mainly consists of a powered needle electrode enclosed in a conical quartz tube and grounded deionized water electrode. The discharges in the gas-phase, as well as in the two-phase, exhibit two discharge modes, i.e., the low current glow-like diffuse mode and the high current streamer-like constrict mode, with a mode transition, which exhibits a negative resistance of the discharges. The optical emission spectral analysis shows that the stronger diffusion of the water vapor into the discharge region in the two-phase discharges boosts up themore » generation of OH (A–X) radicals, and consequently, leads to a higher rotational temperature in the water-phase plasma plume than that of the gas-phase discharges. Both the increase of the power input and the decrease of the argon flow rate result in the increase of the rotational temperature in the plasma plume of the water-phase discharge. The stable two-phase discharges with a long plasma plume in the water-phase under a low power input and gas flow rate may show a promising prospect for the degradation of organic pollutants, e.g., printing and dyeing wastewater, in the field of environmental protection.« less

Application of PBPK modelling in drug discovery and development at Pfizer.

PubMed

Jones, Hannah M; Dickins, Maurice; Youdim, Kuresh; Gosset, James R; Attkins, Neil J; Hay, Tanya L; Gurrell, Ian K; Logan, Y Raj; Bungay, Peter J; Jones, Barry C; Gardner, Iain B

2012-01-01

Early prediction of human pharmacokinetics (PK) and drug-drug interactions (DDI) in drug discovery and development allows for more informed decision making. Physiologically based pharmacokinetic (PBPK) modelling can be used to answer a number of questions throughout the process of drug discovery and development and is thus becoming a very popular tool. PBPK models provide the opportunity to integrate key input parameters from different sources to not only estimate PK parameters and plasma concentration-time profiles, but also to gain mechanistic insight into compound properties. Using examples from the literature and our own company, we have shown how PBPK techniques can be utilized through the stages of drug discovery and development to increase efficiency, reduce the need for animal studies, replace clinical trials and to increase PK understanding. Given the mechanistic nature of these models, the future use of PBPK modelling in drug discovery and development is promising, however, some limitations need to be addressed to realize its application and utility more broadly.

Short communication: cheminformatics analysis to identify predictors of antiviral drug penetration into the female genital tract.

PubMed

Thompson, Corbin G; Sedykh, Alexander; Nicol, Melanie R; Muratov, Eugene; Fourches, Denis; Tropsha, Alexander; Kashuba, Angela D M

2014-11-01

The exposure of oral antiretroviral (ARV) drugs in the female genital tract (FGT) is variable and almost unpredictable. Identifying an efficient method to find compounds with high tissue penetration would streamline the development of regimens for both HIV preexposure prophylaxis and viral reservoir targeting. Here we describe the cheminformatics investigation of diverse drugs with known FGT penetration using cluster analysis and quantitative structure-activity relationships (QSAR) modeling. A literature search over the 1950-2012 period identified 58 compounds (including 21 ARVs and representing 13 drug classes) associated with their actual concentration data for cervical or vaginal tissue, or cervicovaginal fluid. Cluster analysis revealed significant trends in the penetrative ability for certain chemotypes. QSAR models to predict genital tract concentrations normalized to blood plasma concentrations were developed with two machine learning techniques utilizing drugs' molecular descriptors and pharmacokinetic parameters as inputs. The QSAR model with the highest predictive accuracy had R(2)test=0.47. High volume of distribution, high MRP1 substrate probability, and low MRP4 substrate probability were associated with FGT concentrations ≥1.5-fold plasma concentrations. However, due to the limited FGT data available, prediction performances of all models were low. Despite this limitation, we were able to support our findings by correctly predicting the penetration class of rilpivirine and dolutegravir. With more data to enrich the models, we believe these methods could potentially enhance the current approach of clinical testing.

Pharmacokinetic-pharmacodynamic modelling of the antihistaminic (H1) effect of bilastine.

PubMed

Jauregizar, Nerea; de la Fuente, Leire; Lucero, Maria Luisa; Sologuren, Ander; Leal, Nerea; Rodríguez, Mónica

2009-01-01

To model the pharmacokinetic and pharmacodynamic relationship of bilastine, a new histamine H(1) receptor antagonist, from single- and multiple-dose studies in healthy adult subjects. The pharmacokinetic model was developed from different single-dose and multiple-dose studies. In the single-dose studies, a total of 183 subjects received oral doses of bilastine 2.5, 5, 10, 20, 50, 100, 120, 160, 200 and 220 mg. In the multiple-dose studies, 127 healthy subjects received bilastine 10, 20, 40, 50, 80, 100, 140 or 200 mg/day as multiple doses during a 4-, 7- or 14-day period. The pharmacokinetic profile of bilastine was investigated using a simultaneous analysis of all concentration-time data by means of nonlinear mixed-effects modelling population pharmacokinetic software NONMEM version 6.1. Plasma concentrations were modelled according to a two-compartment open model with first-order absorption and elimination. For the pharmacodynamic analysis, the inhibitory effect of bilastine (inhibition of histamine-induced wheal and flare) was assessed on a preselected time schedule, and the predicted typical pharmacokinetic profile (based on the pharmacokinetic model previously developed) was used. An indirect response model was developed to describe the pharmacodynamic relationships between flare or wheal areas and bilastine plasma concentrations. Finally, once values of the concentration that produced 50% inhibition (IC(50)) had been estimated for wheal and flare effects, simulations were carried out to predict plasma concentrations for the doses of bilastine 5, 10 and 20 mg at steady state (72-96 hours). A non-compartmental analysis resulted in linear kinetics of bilastine in the dose range studied. Bilastine was characterized by two-compartmental kinetics with a rapid-absorption phase (first-order absorption rate constant = 1.50 h(-1)), plasma peak concentrations were observed at 1 hour following administration and the maximal response was observed at approximately 4 hours or later. Concerning the selected pharmacodynamic model to fit the data (type I indirect response model), this selection is attributable to the presence of inhibitory bilastine plasma concentrations that decrease the input response function, i.e. the production of the skin reaction. This model resulted in the best fit of wheal and flare data. The estimates (with relative standard errors expressed in percentages in parentheses) of the apparent zero-order rate constant for flare or wheal spontaneous appearance (k(in)), the first-order rate constant for flare or wheal disappearance (k(out)) and bilastine IC(50) values were 0.44 ng/mL/h (14.60%), 1.09 h(-1) (15.14%) and 5.15 ng/mL (16.16%), respectively, for wheal inhibition, and 11.10 ng/mL/h (8.48%), 1.03 h(-1) (8.35%) and 1.25 ng/mL (14.56%), respectively, for flare inhibition. The simulation results revealed that bilastine plasma concentrations do not remain over the IC(50) value throughout the inter-dose period for doses of 5 and 10 mg. However, with a dose of 20 mg of bilastine administered every 24 hours, plasma concentrations remained over the IC(50) value during the considered period for the flare effect, and up to 20 hours for the wheal effect. Pharmacokinetic and pharmacodynamic relationships of bilastine were reliably described with the use of an indirect response pharmacodynamic model; this led to an accurate prediction of the pharmacodynamic activity of bilastine.

Midplane neutral density profiles in the National Spherical Torus Experiment

DOE PAGES

Stotler, D. P.; Scotti, F.; Bell, R. E.; ...

2015-08-13

Atomic and molecular density data in the outer midplane of NSTX [Ono et al., Nucl. Fusion 40, 557 (2000)] are inferred from tangential camera data via a forward modeling procedure using the DEGAS 2 Monte Carlo neutral transport code. The observed Balmer-β light emission data from 17 shots during the 2010 NSTX campaign display no obvious trends with discharge parameters such as the divertor Balmer-α emission level or edge deuterium ion density. Simulations of 12 time slices in 7 of these discharges produce molecular densities near the vacuum vessel wall of 2–8 × 10 17 m –3 and atomic densitiesmore » ranging from 1 to 7 ×10 16 m –3; neither has a clear correlation with other parameters. Validation of the technique, begun in an earlier publication, is continued with an assessment of the sensitivity of the simulated camera image and neutral densities to uncertainties in the data input to the model. The simulated camera image is sensitive to the plasma profiles and virtually nothing else. The neutral densities at the vessel wall depend most strongly on the spatial distribution of the source; simulations with a localized neutral source yield densities within a factor of two of the baseline, uniform source, case. Furthermore, the uncertainties in the neutral densities associated with other model inputs and assumptions are ≤ 50%.« less

Catastrophic cooling and cessation of heating in the solar corona

NASA Astrophysics Data System (ADS)

Peter, H.; Bingert, S.; Kamio, S.

2012-01-01

Context. Condensations in the more than 106 K hot corona of the Sun are commonly observed in the extreme ultraviolet (EUV). While their contribution to the total solar EUV radiation is still a matter of debate, these condensations certainly provide a valuable tool for studying the dynamic response of the corona to the heating processes. Aims: We investigate different distributions of energy input in time and space to investigate which process is most relevant for understanding these coronal condensations. Methods: For a comparison to observations we synthesize EUV emission from a time-dependent, one-dimensional model for coronal loops, where we employ two heating scenarios: simply shutting down the heating and a model where the heating is very concentrated at the loop footpoints, while keeping the total heat input constant. Results: The heating off/on model does not lead to significant EUV count rates that one observes with SDO/AIA. In contrast, the concentration of the heating near the footpoints leads to thermal non-equilibrium near the loop top resulting in the well-known catastrophic cooling. This process gives a good match to observations of coronal condensations. Conclusions: This shows that the corona needs a steady supply of energy to support the coronal plasma, even during coronal condensations. Otherwise the corona would drain very fast, too fast to even form a condensation. Movies are available in electronic form at http://www.aanda.org

Effect of plasma arc welding variables on fusion zone grain size and hardness of AISI 321 austenitic stainless steel

NASA Astrophysics Data System (ADS)

Kondapalli, S. P.

2017-12-01

In the present work, pulsed current microplasma arc welding is carried out on AISI 321 austenitic stainless steel of 0.3 mm thickness. Peak current, Base current, Pulse rate and Pulse width are chosen as the input variables, whereas grain size and hardness are considered as output responses. Response surface method is adopted by using Box-Behnken Design, and in total 27 experiments are performed. Empirical relation between input and output response is developed using statistical software and analysis of variance (ANOVA) at 95% confidence level to check the adequacy. The main effect and interaction effect of input variables on output response are also studied.

Influence of Plasma Unsteadiness on the Spectrum and Shape of Microwave Pulses in a Plasma Relativistic Microwave Amplifier

NASA Astrophysics Data System (ADS)

Kartashov, I. N.; Kuzelev, M. V.; Strelkov, P. S.; Tarakanov, V. P.

2018-02-01

Dependence of the shape of a microwave pulse in a plasma relativistic microwave amplifier (PRMA) on the initial plasma electron density in the system is detected experimentally. Depending on the plasma density, fast disruption of amplification, stable operation of the amplifier during the relativistic electron beam (REB) pulse, and its delayed actuation can take place. A reduction in the output signal frequency relative to the input frequency is observed experimentally. The change in the shape of the microwave signal and the reduction in its frequency are explained by a decrease in the plasma density in the system. The dynamics of the plasma density during the REB pulse is determined qualitatively from the experimental data by using the linear theory of a PRMA with a thin-wall hollow electron beam. The processes in a PRMA are analyzed by means of the KARAT particle-in-cell code. It is shown that REB injection is accompanied by an increase in the mean energy of plasma electrons and a significant decrease in their density.

The cathode plasma simulation

NASA Astrophysics Data System (ADS)

Suksila, Thada

Since its invention at the University of Stuttgart, Germany in the mid-1960, scientists have been trying to understand and explain the mechanism of the plasma interaction inside the magnetoplasmadynamics (MPD) thruster. Because this thruster creates a larger level of efficiency than combustion thrusters, this MPD thruster is the primary cadidate thruster for a long duration (planetary) spacecraft. However, the complexity of this thruster make it difficult to fully understand the plasma interaction in an MPD thruster while operating the device. That is, there is a great deal of physics involved: the fluid dynamics, the electromagnetics, the plasma dynamics, and the thermodynamics. All of these physics must be included when an MPD thruster operates. In recent years, a computer simulation helped scientists to simulate the experiments by programing the physics theories and comparing the simulation results with the experimental data. Many MPD thruster simulations have been conducted: E. Niewood et al.[5], C. K. J. Hulston et al.[6], K. D. Goodfellow[3], J Rossignol et al.[7]. All of these MPD computer simulations helped the scientists to see how quickly the system responds to the new design parameters. For this work, a 1D MPD thruster simulation was developed to find the voltage drop between the cathode and the plasma regions. Also, the properties such as thermal conductivity, electrical conductivity and heat capacity are temperature and pressure dependent. These two conductivity and heat capacity are usually definded as constant values in many other models. However, this 1D and 2D cylindrical symmetry MPD thruster simulations include both temperature and pressure effects to the electrical, thermal conductivities and heat capacity values interpolated from W. F. Ahtye [4]. Eventhough, the pressure effect is also significant; however, in this study the pressure at 66 Pa was set as a baseline. The 1D MPD thruster simulation includes the sheath region, which is the interface between the plasma and the cathode regions. This sheath model [3] has been fully combined in the 1D simulation. That is, the sheath model calculates the heat flux and the sheath voltage by giving the temperature and the current density. This sheath model must be included in the simulation, as the sheath region is treated differently from the main plasma region. For our 2D cylindrical symmetry simulation, the dimensions of the cathode, the anode, the total current, the pressure, the type of gases, the work function can be changed in the input process as needed for particular interested. Also, the sheath model is still included and fully integrated in this 2D cylindrical symmetry simulation at the cathode surface grids. In addition, the focus of the 2D cylindrical symmetry simulation is to connect the properties on the plasma and the cathode regions on the cathode surface until the MPD thruster reach steady state and estimate the plasma arc attachement edge, electroarc edge, on the cathode surface. Finally, we can understand more about the behavior of an MPD thruster under many different conditions of 2D cylindrical symmetry MPD thruster simulations.

Characterization of Dust-Plasma Interactions In Non-Thermal Plasmas Under Low Pressure and the Atmospheric Pressure

NASA Astrophysics Data System (ADS)

Bilik, Narula

This dissertation research focuses on the experimental characterization of dust-plasma interactions at both low and atmospheric pressure. Its goal is to fill the knowledge gaps in (1) the fundamental research of low pressure dusty plasma electrons, which mainly relied on models with few experimental results; and (2) the nanoparticle synthesis process in atmospheric pressure uniform glow plasmas (APGDs), which is largely unexplored in spite of the economical advantage of APGDs in nanotechnology. The low pressure part of the dissertation research involves the development of a complete diagnostic process for an argon-siline capacitively-coupled RF plasma. The central part of the diagnostic process is the Langmuir probe measurement of the electron energy probability function (EEPF) in a dusty plasma, which has never been measured before. This is because the dust particles in the plasma cause severe probe surface contamination and consequently distort the measurement. This problem is solved by adding a solenoid-actuated shield structure to the Langmuir probe, which physically protects the Langmuir probe from the dust particle deposition to ensure reliable EEPF measurements. The dusty plasma EEPFs are characterized by lower electron density and higher electron temperature accompanied by a drop in the low energy electron population. The Langmuir probe measurement is complemented with other characterizations including the capacitive probe measurement, power measurement, and dust particle collection. The complete diagnostic process then gives a set of local plasma parameters as well as the details of the dust-electron interactions reflected in the EEPFs. This set of data serves as input for an analytical model of nanoparticle charging to yield the time evolution of nanoparticle size and charge in the dusty plasma. The atmospheric pressure part of the dissertation focuses on the design and development of an APGD for zinc oxide nanocrystal synthesis. One of the main difficulties in maintaining an APGD is ensuring its uniformity over large discharge volume. By examining past atmospheric pressure plasma reactor designs and looking into the details of the atmospheric pressure gas breakdown mechanism, three design features are proposed to ensure the APGD uniformity. These include the use of a dielectric barrier and the RF driving frequency, as well as a pre-ionization technique achieved by having a non-uniform gap spacing in a capacitively-coupled concentric cylinder reactor. The resulting APGD reactor operates stably in the abnormal glow regime using either helium or argon as the carrier gas. Diethylzinc (DEZ) and oxygen precursors are injected into the APGD to form zinc oxide nanocrystals. The physical and optical properties of these nanocrystals are characterized, and the system parameters that impact the nanoparticle size and deposition rate are identified.

Robust input design for nonlinear dynamic modeling of AUV.

PubMed

Nouri, Nowrouz Mohammad; Valadi, Mehrdad

2017-09-01

Input design has a dominant role in developing the dynamic model of autonomous underwater vehicles (AUVs) through system identification. Optimal input design is the process of generating informative inputs that can be used to generate the good quality dynamic model of AUVs. In a problem with optimal input design, the desired input signal depends on the unknown system which is intended to be identified. In this paper, the input design approach which is robust to uncertainties in model parameters is used. The Bayesian robust design strategy is applied to design input signals for dynamic modeling of AUVs. The employed approach can design multiple inputs and apply constraints on an AUV system's inputs and outputs. Particle swarm optimization (PSO) is employed to solve the constraint robust optimization problem. The presented algorithm is used for designing the input signals for an AUV, and the estimate obtained by robust input design is compared with that of the optimal input design. According to the results, proposed input design can satisfy both robustness of constraints and optimality. Copyright © 2017 ISA. Published by Elsevier Ltd. All rights reserved.

One- and two-dimensional modeling of argon K-shell emission from gas-puff Z-pinch plasmas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thornhill, J. W.; Chong, Y. K.; Apruzese, J. P.

2007-06-15

In this paper, a theoretical model is described and demonstrated that serves as a useful tool for understanding K-shell radiating Z-pinch plasma behavior. Such understanding requires a self-consistent solution to the complete nonlocal thermodynamic equilibrium kinetics and radiation transport in order to realistically model opacity effects and the high-temperature state of the plasma. For this purpose, we have incorporated into the MACH2 two-dimensional magnetohydrodynamic (MHD) code [R. E. Peterkin et al., J. Comput. Phys. 140, 148 (1998)] an equation of state, called the tabular collisional radiative equilibrium (TCRE) model [J. W. Thornhill et al., Phys. Plasmas 8, 3480 (2001)], thatmore » provides reasonable approximations to the plasma's opacity state. MACH2 with TCRE is applied toward analyzing the multidimensional implosion behavior that occurred in Decade Quad (DQ) [D. Price et al., Proceedings of the 12th IEEE Pulsed Power Conference, Monterey, CA, edited by C. Stallings and H. Kirbie (IEEE, New York, 1999), p. 489] argon gas puff experiments that employed a 12 cm diameter nozzle with and without a central gas jet on axis. Typical peak drive currents and implosion times in these experiments were {approx}6 MA and {approx}230 ns. By using Planar Laser Induced Fluorescence measured initial density profiles as input to the calculations, the effect these profiles have on the ability of the pinch to efficiently produce K-shell emission can be analyzed with this combined radiation-MHD model. The calculated results are in agreement with the experimental result that the DQ central-jet configuration is superior to the no-central-jet experiment in terms of producing more K-shell emission. These theoretical results support the contention that the improved operation of the central-jet nozzle is due to the better suppression of instabilities and the higher-density K-shell radiating conditions that the central-jet configuration promotes. When we applied the model toward projecting argon K-shell yield behavior for Sandia National Laboratories' ZR machine ({approx}25 MA peak drive currents, {approx}100 ns implosion times) [D. McDaniel et al., Proceedings of the 5th International Conference on Dense Z-Pinches, Albuquerque, NM, 2002, edited by J. Davis, C. Deeney, and N. R. Pereira (American Institute of Physics, New York, 2002), Vol. 651, p. 23] for experiments that utilize the 12 cm diameter central-jet nozzle configuration, it predicts over 1 MJ of K-shell emission is attainable.« less

Improved Temperature Diagnostic for Non-Neutral Plasmas with Single-Electron Resolution

NASA Astrophysics Data System (ADS)

Shanman, Sabrina; Evans, Lenny; Fajans, Joel; Hunter, Eric; Nelson, Cheyenne; Sierra, Carlos; Wurtele, Jonathan

2016-10-01

Plasma temperature diagnostics in a Penning-Malmberg trap are essential for reliably obtaining cold, non-neutral plasmas. We have developed a setup for detecting the initial electrons that escape from a trapped pure electron plasma as the confining electrode potential is slowly reduced. The setup minimizes external noise by using a silicon photomultiplier to capture light emitted from an MCP-amplified phosphor screen. To take advantage of this enhanced resolution, we have developed a new plasma temperature diagnostic analysis procedure which takes discrete electron arrival times as input. We have run extensive simulations comparing this new discrete algorithm to our existing exponential fitting algorithm. These simulations are used to explore the behavior of these two temperature diagnostic procedures at low N and at high electronic noise. This work was supported by the DOE DE-FG02-06ER54904, and the NSF 1500538-PHY.

Study of the physical discharge properties of a Ar/O2 DC plasma jet

NASA Astrophysics Data System (ADS)

Barkhordari, A.; Ganjovi, A.; Mirzaei, I.; Falahat, A.

2018-03-01

In this paper, the physical properties of plasma discharge in a manufactured DC plasma jet operating with the Ar/O2 gaseous mixture are studied. Moreover, the optical emission spectroscopy technique is used to perform the experimental measurements. The obtained emission spectra are analyzed and, the plasma density, rotational, vibrational and electronic temperature are calculated. The NO emission lines from {NO }γ( A2 Σ^{+} \\to {X}2 Πr ) electronic transition are observed. It is seen that, at the higher argon contributions in Ar/O2 gaseous mixture, the emission intensities from argon ions will increase. Moreover, while the vibrational and excitation temperatures are increased at the higher input DC currents, they will decrease at the higher Ar percentages in the Ar/O2 gaseous mixture. Furthermore, at the higher DC currents and Ar contributions, both the plasma electron density and dissociation fraction of oxygen atoms are increased.

Treatment of refractory powders by a novel, high enthalpy dc plasma

NASA Astrophysics Data System (ADS)

Pershin, L.; Mitrasinovic, A.; Mostaghimi, J.

2013-06-01

Thermophysical properties of CO2-CH4 mixtures at high temperatures are very attractive for materials processing. In comparison with argon, at the same temperature, such a mixture possesses much higher enthalpy and higher thermal conductivity. At high temperatures, CO2-CH4 mixture has a complex composition with strong presence of CO which, in the case of powder treatment, could reduce oxidation. In this work, a dc plasma torch with graphite cathode was used to study the effect of plasma gas composition on spheroidization of tungsten carbide and alumina powders. Two different gas compositions were used to generate the plasma while the torch current was kept at 300 A. Various techniques were employed to assess the average concentration of carbides and oxides and the final shape of the treated powders. Process parameters such as input power and plasma gas composition allow controlling the degree of powder oxidation and spheroidization of high melting point ceramic powders.

Neutron and Gamma-ray Detection in Reversed-Field Pinch Deuterium Plasmas in the RFX-mod Device

NASA Astrophysics Data System (ADS)

Zuin, Matteo; Stevanato, Luca; Martines, Emilio; Gonzalez, Winder; Cavazzana, Roberto; Cester, Davide; Nebbia, G.; Sajo-Bohus, Laszlo; Viesti, Giuseppe

2014-10-01

An experimental analysis of neutron and gamma-ray fluxes exiting purely ohmically heated plasmas in reversed-field pinch (RFP) configuration is presented. The diagnostic system, installed in the RFX-mod, is made of 2 scintillators (EJ-301 liquid and NaI(Tl)) coupled to flat-panel photomultipliers, which can be operated under magnetic fields. The production of neutrons and gamma rays in Deuterium plasmas is found to be strongly dependent on the Ohmic input power, with a threshold value of about 1.2 MA in terms of plasma current level, below which low levels of gamma rays and almost no neutrons are detected. Neutron and gamma production is characterized by a bursty behavior, correlated to the spontaneous magnetic reconnection events, occurring almost cyclically in the RFP plasmas. The role of ion heating and particle acceleration during such events is discussed.

Comparison between two models of energy balance in coronal loops

NASA Astrophysics Data System (ADS)

Mac Cormack, C.; López Fuentes, M.; Vásquez, A. M.; Nuevo, F. A.; Frazin, R. A.; Landi, E.

2017-10-01

In this work we compare two models to analyze the energy balance along coronal magnetic loops. For the first stationary model we deduce an expression of the energy balance along the loops expressed in terms of quantities provided by the combination of differential emission measure tomography (DEMT) applied to EUV images time series and potential extrapolations of the coronal magnetic field. The second applied model is a 0D hydrodynamic model that provides the evolution of the average properties of the coronal plasma along the loops, using as input parameters the loop length and the heating rate obtained with the first model. We compare the models for two Carrington rotations (CR) corresponding to different periods of activity: CR 2081, corresponding to a period of minimum activity observed with the Extreme Ultraviolet Imager (EUVI) on board of the Solar Terrestrial Relations Observatory (STEREO), and CR 2099, corresponding to a period of activity increase observed with the Atmospheric Imaging Assembly (AIA) on board the Solar Dynamics Observatory (SDO). The results of the models are consistent for both rotations.

Creating and measuring white dwarf photospheres in a terrestrial laboratory

NASA Astrophysics Data System (ADS)

Falcon, Ross Edward

2014-08-01

As the ultimate fate of nearly all stars, including our Sun, white dwarfs (WDs) hold rich and informative histories in their observable light. To determine a fundamental parameter of WDs, mass, we perform the first measurement of the average gravitational redshift of an ensemble of WDs. We find a larger mean mass than that determined from the primary and expansive technique known as the spectroscopic method. The potential inaccuracy of this method has broad astrophysical implications, including for our understanding of Type 1a supernova progenitors and for constraining the age of the Universe. This motivates us to investigate the WD atmosphere models used with the spectroscopic method, particularly the input theoretical line profiles, by developing a new experimental platform to create plasmas at WD photospheric conditions (Te~1 eV, ne~1017 cm-3). Instead of observing WD spectra to infer the plasma conditions at the surface of the star, we set the conditions and measure the emergent spectra in the laboratory. X-rays from a z-pinch dynamic hohlraum generated at the Z Pulsed Power Facility at Sandia National Laboratories irradiate a gas cell to initiate formation of a large (120x20x10 mm or 24 cm3) plasma. We observe multiple Balmer lines from our plasma in emission and in absorption simultaneously along relatively long (~120 mm) lines of sight perpendicular to the heating radiation. Using a large, radiation-driven plasma aides us to achieve homogeneity along our observed lines of sight. With time-resolved spectroscopy we measure lines at a range of electron densities that spans an order of magnitude, and we do this within one pulsed power shot experiment. Observing our plasma in absorption not only provides the signal-to-noise to measure relative line shapes, it allows us to measure relative line strengths because the lines share the same lower level population. This constrains the theoretical reduction factors used to describe ionization potential depression or the occupation probabilities associated with these Balmer lines. We compare our measured line shapes with the theoretical ones used in WD atmosphere models as part of the first fruits of this rich experimental platform.

The development of the miniaturized waveform receiver with the function measuring Antenna Impedance in space plasmas

NASA Astrophysics Data System (ADS)

Ishii, H.; Kojima, H.; Fukuhara, H.; Okada, S.; Yamakawa, H.

2012-04-01

Plasma wave is one of the most essential physical quantities in the solar terrestrial physics. The role of plasma wave receiver onboard satellites is to detect plasma waves in space with a good signal to noise ratio. There are two types of plasma wave receivers, the sweep frequency analyzer and the waveform capture. While the sweep frequency analyzer provides plasma wave spectra, the waveform capture obtains waveforms with phase information that is significant in studying nonlinear phenomena. Antenna sensors to observe electric fields of the plasma waves show different features in plasmas from in vacuum. The antenna impedances have specific characteristics in the frequency domain because of the dispersion of plasmas. These antenna impedances are expressed with complex number. We need to know not only the antenna impedances but also the transfer functions of plasma wave receiver's circuits in order to calibrate observed waveforms precisely. The impedances of the electric field antennas are affected by a state of surrounding plasmas. Since satellites run through various regions with different plasma parameters, we precisely should measure the antenna impedances onboard spacecraft. On the contrary, we can obtain the plasma density and by measuring the antenna impedances. Several formulas of the antenna impedance measurement system were proposed. A synchronous detection method is used on the BepiColombo Mercury Magnetospheric Orbiter (MMO), which will be launched in 2014. The digital data are stored in the onboard memory. They are read out and converted to the analog waveforms by D/A converter. They are fed into the input of the preamplifiers of antenna sensors through a resistor. We can calculate a transfer function of the circuit by applying the synchronous detection method to the output waveform from waveform receivers and digital data as a signal source. The size of this system is same as an A5 board. In recent years, Application Specific Integrated Circuit (ASIC) is in attention which is a technique to integrate large scale and complicated circuits. Lots of ASICs have been applied to high energy astrophysics. In this paper, we show our attempt to miniaturize the antennas impedances measurement system and Waveform Capture using the analogue ASIC. We design 8bits segment D/A converter that is implemented inside the waveform receiver ASIC chip. We improve input logic of the D/A converter to generate very weak signals accurately. The designed chip realizes the measurement of the antenna impedance as well as the waveform observation in the board size of business cards.

Discharge conditions for CW and pulse-modulated surface-wave plasmas in low-temperature sterilization

NASA Astrophysics Data System (ADS)

Xu, L.; Terashita, F.; Nonaka, H.; Ogino, A.; Nagata, T.; Koide, Y.; Nanko, S.; Kurawaki, I.; Nagatsu, M.

2006-01-01

The discharge conditions required for low-temperature plasma sterilization were investigated using low-pressure surface-wave plasma (SWP). The discharge conditions for both continuous wave (CW) and pulse-modulated SWPs in low-temperature sterilization of Geobacillus stearothermophilus with a population of 1.5 × 106 and 3.0 × 106 were studied by varying the microwave input power from 500 W to 3 kW, and the effective plasma treatment time from 40 to 300 s. Results showed that sterilization was possible in a shorter treatment time using a higher microwave power for both CW and pulse-modulated SWPs. Pulse-modulated SWPs gave effective sterilization at a temperature roughly 10 to 20 °C below that of CW SWPs under the same average microwave power.

Characterization of plasma sprayed and explosively consolidated simulated lunar soil

DOE Office of Scientific and Technical Information (OSTI.GOV)

Powell, S.J.; Inal, O.T.; Smith, M.F.

1997-06-01

Two methods for the use of lunar materials for the construction of shelters on the Moon are being proposed: explosive consolidation of the soil into structural components and plasma spraying of the soil to join components. The plasma-sprayed coating would also provide protection from the intense radiation. In this work, a mare simulant was plasma-sprayed onto a stainless steel substrate. Deposition of a 0.020 inch coating using power inputs of 23, 25, 27 and 29 kW were compared. Hardness of the coatings increased with each increase of power to the system, while porosity at the interface decreased. All coatings exhibitedmore » good adhesion. Simultaneously, an explosively consolidated sample was similarly characterized to afford a comparison of structural features associated with each mode of proposed use.« less

Carbon fiber manufacturing via plasma technology

DOEpatents

Paulauskas, Felix L.; Yarborough, Kenneth D.; Meek, Thomas T.

2002-01-01

The disclosed invention introduces a novel method of manufacturing carbon and/or graphite fibers that avoids the high costs associated with conventional carbonization processes. The method of the present invention avoids these costs by utilizing plasma technology in connection with electromagnetic radiation to produce carbon and/or graphite fibers from fully or partially stabilized carbon fiber precursors. In general, the stabilized or partially stabilized carbon fiber precursors are placed under slight tension, in an oxygen-free atmosphere, and carbonized using a plasma and electromagnetic radiation having a power input which is increased as the fibers become more carbonized and progress towards a final carbon or graphite product. In an additional step, the final carbon or graphite product may be surface treated with an oxygen-plasma treatment to enhance adhesion to matrix materials.

Plasma-chemical processes accompanying discharge in air excited by a microwave beam

NASA Astrophysics Data System (ADS)

Askar'ian, G. A.; Batanov, G. M.; Gritsinin, S. I.; Kossyi, I. A.; Kostinskii, A. Iu.

1990-11-01

Experimental results are presented on plasma-chemical processes of nitrogen oxidation and ozone production accompanying microwave discharge in dry air and in nitrogen-oxygen mixtures. The degree of nitrogen oxidation and the energy expenditure toward the formation of oxides as a function of discharge conditions are established. The experimental results can be explained by assuming oxidation reactions of electron-excited metastable nitrogen molecules by oxygen atoms. Low ozone concentrations in the discharge indicate a significant energy input into the gas.

Morphology of zirconia particles exposed to D.C. arc plasma jet

NASA Technical Reports Server (NTRS)

Zaplatynsky, Isidor

1987-01-01

Zirconia particles were sprayed into water with an arc plasma gun in order to determine the effect of various gun operating parameters on their morphology. The collected particles were examined by XRD and SEM techniques. A correlation was established between the content of spherical (molten) particles and the operating parameters by visual inspection and regression analysis. It was determined that the composition of the arc gas and the power input were the predominant parameters that affected the melting of zirconia particles.

Cylindrical stationary striations in surface wave produced plasma columns of argon

NASA Astrophysics Data System (ADS)

Kumar, Rajneesh; Kulkarni, Sanjay V.; Bora, Dhiraj

2007-12-01

Striations are a good example of manifestation of a glow discharge. In the present investigation, stationary striations in the surface wave produced plasma column are formed. Physical parameters (length, number, etc.) of such striations can be controlled by operating parameters. With the help of bifurcation theory, experimental results are explained by considering two-step ionization in the surface wave discharge mechanism in argon gas. It is also observed that the bifurcation parameter is a function of input power, working pressure, and tube radius.

Role of external torque in the formation of ion thermal internal transport barriers

NASA Astrophysics Data System (ADS)

Jhang, Hogun; Kim, S. S.; Diamond, P. H.

2012-04-01

We present an analytic study of the impact of external torque on the formation of ion internal transport barriers (ITBs). A simple analytic relation representing the effect of low external torque on transport bifurcations is derived based on a two field transport model of pressure and toroidal momentum density. It is found that the application of an external torque can either facilitate or hamper bifurcation in heat flux driven plasmas depending on its sign relative to the direction of intrinsic torque. The ratio between radially integrated momentum (i.e., external torque) density to power input is shown to be a key macroscopic control parameter governing the characteristics of bifurcation.

Development of a 1.5D plasma transport code for coupling to full orbit runaway electron simulations

NASA Astrophysics Data System (ADS)

Lore, J. D.; Del Castillo-Negrete, D.; Baylor, L.; Carbajal, L.

2017-10-01

A 1.5D (1D radial transport + 2D equilibrium geometry) plasma transport code is being developed to simulate runaway electron generation, mitigation, and avoidance by coupling to the full-orbit kinetic electron transport code KORC. The 1.5D code solves the time-dependent 1D flux surface averaged transport equations with sources for plasma density, pressure, and poloidal magnetic flux, along with the Grad-Shafranov equilibrium equation for the 2D flux surface geometry. Disruption mitigation is simulated by introducing an impurity neutral gas `pellet', with impurity densities and electron cooling calculated from ionization, recombination, and line emission rate coefficients. Rapid cooling of the electrons increases the resistivity, inducing an electric field which can be used as an input to KORC. The runaway electron current is then included in the parallel Ohm's law in the transport equations. The 1.5D solver will act as a driver for coupled simulations to model effects such as timescales for thermal quench, runaway electron generation, and pellet impurity mixtures for runaway avoidance. Current progress on the code and details of the numerical algorithms will be presented. Work supported by the US DOE under DE-AC05-00OR22725.

Modeling and characterization of field-enhanced corona discharge in ozone-generator diode

NASA Astrophysics Data System (ADS)

Patil, Jagadish G.; Vijayan, T.

2010-02-01

Electric field enhanced corona plasma discharge in ozone generator diode of axial symmetry has been investigated and characterized in theory. The cathode K of diode is made of a large number of sharpened nozzles arranged on various radial planes on the axial mast and pervaded in oxygen gas inside the anode cup A, produces high fields over MV/m and aids in the formation of a corona plume of dense ozone cloud over the cathode surface. An r-z finite difference scheme has been devised and employed to numerically determine the potential and electric field distributions inside the diode. The analyses of cathode emissions revealed a field emission domain conformed to modified Child-Langmuir diode-current. Passage of higher currents (over μA) in shorter A-K gaps d gave rise to cathode heated plasma extending from the corona to Saha regimes depending on local temperature. Plasma densities of order 102-106 m-3 are predicted in these. For larger d however, currents are smaller and heating negligible and a negative corona favoring ozone formation is attained. High ozone yields about 20 per cent of oxygen input is predicted in this domain. The generator so developed will be applied to various important applications such as, purification of ambient air /drinking water, ozone therapy, and so on.

Hot ion plasma production in HIP-1 using water-cooled hollow cathodes

NASA Technical Reports Server (NTRS)

Reinmann, J. J.; Lauver, M. R.; Patch, R. W.; Layman, R. W.; Snyder, A.

1975-01-01

The paper reports on hot-ion plasma experiments conducted in a magnetic mirror facility. A steady-state E x B plasma was formed by applying a strong radially inward dc electric field near the mirror throats. Most of the results were for hydrogen, but deuterium and helium plasmas were also studied. Three water-cooled hollow cathodes were operated in the hot-ion plasma mode with the following results: (1) thermally emitting cathodes were not required to achieve the hot-ion mode; (2) steady-state operation (several minutes) was attained; (3) input powers greater than 40 kW were achieved; (4) cathode outside diameters were increased from 1.2 cm (uncooled) to 4.4 cm (water-cooled); (5) steady-state hydrogen plasmas with ion temperatures from 185 to 770 eV and electron temperatures from 5 to 21 eV were produced. Scaling relations were empirically obtained for discharge current, ion temperature, electron temperature, and relative ion density as a function of hydrogen gas feed rate, magnetic field, and cathode voltage.

Characteristics of the NASA Lewis bumpy-torus plasma generated with positive applied potentials

NASA Technical Reports Server (NTRS)

Roth, J. R.; Gerdin, G. A.; Richardson, R. W.

1976-01-01

Experimental observations were made during steady-state operation of a bumpy-torus plasma at input powers up to 150 kW in deuterium and helium gas and with positive potentials applied to the midplane electrodes. In this steady-state ion heating method a modified Penning discharge is operated such that the plasma is acted upon by a combination of strong electric and magnetic fields. Experimental investigation of a deuterium plasma revealed electron temperatures from 14 to 140 eV and ion kinetic temperatures from 160 to 1785 eV. At least two distinct modes of operation exist. Experimental data shows that the average ion residence time in the plasma is virtually independent of the magnetic field strength. Data was taken when all 12 anode rings were at high voltage, and in other symmetric configurations in which the toroidal plasma was generated by applying positive potentials to six anode rings, three anode rings, and a single anode ring.

How does the predicted geomagnetic main field variation alter the thermosphere-ionosphere storm-time response?

NASA Astrophysics Data System (ADS)

Maute, A. I.; Lu, G.; Richmond, A. D.

2017-12-01

Earth's magnetic main field plays an important role in the thermosphere-ionosphere (TI) system, as well as its coupling to Earth's magnetosphere. The ionosphere consists of a weakly ionized plasma strongly influenced by the main field and embedded in the thermosphere. Therefore, ion-neutral coupling and ionospheric electrodynamics can influence the plasma distribution and neutral dynamics. There are strong longitude variations of the TI storm response. At high latitude magnetosphere-ionosphere coupling is organized by the geomagnetic main field, leading in general to stronger northern middle latitude storm time response in the American sector due to the geomagnetic dipole location. In addition, the weak geomagnetic main field in the American sector leads to larger local ExB drift and can alter the plasma densities. During geomagnetic storms the intense energy input into the high latitude region is redistributed globally, leading to thermospheric heating, wind circulation changes and alterations of the ionospheric electrodynamics. The storm time changes are measurable in the plasma density, ion drift, temperature, neutral composition, and other parameters. All these changes depend, to some degree, on the geomagnetic main field which changes on decadal time scales. In this study, we employ a forecast model of the geomagnetic main field based on data assimilation and geodynamo modeling [Aubert et al., 2015]. The main field model predicts that in 50 years the South Atlantic Anomaly is further weakened by 2 mT and drifts westward by approximately 10o. The dipole axis moves northward and westward by 2o and 6o, respectively. Simulating the March 2015 geomagnetic storm with the Thermosphere-Ionosphere Electrodynamics General Circulation Model (TIE-GCM) driven by the Assimilative Mapping of Ionospheric Electrodynamics (AMIE), we evaluate the thermosphere-ionosphere response using the geomagnetic main field of 2015, 2065, and 2115. We compare the TI response for 2015 with available satellite data, e.g. Swarm and COSMIC, and discuss the changes in the TI response due to the predicted main field changes to identify regions of potential increase and decrease in the storm time response. Aubert, J., Geophys. J. Int. 203, 1738-1751, 2015, doi: 10.1093/gji/ggv394 .

NASCAP user's manual, 1978

NASA Technical Reports Server (NTRS)

Cassidy, J. J., III

1978-01-01

NASCAP simulates the charging process for a complex object in either tenuous plasma (geosynchronous orbit) or ground test (electron gun source) environment. Program control words, the structure of user input files, and various user options available are described in this computer programmer's user manual.

The brain as a system of nested but partially overlapping networks. Heuristic relevance of the model for brain physiology and pathology.

PubMed

Agnati, L F; Guidolin, D; Fuxe, K

2007-01-01

A new model of the brain organization is proposed. The model is based on the assumption that a global molecular network enmeshes the entire central nervous system. Thus, brain extra-cellular and intra-cellular molecular networks are proposed to communicate at the level of special plasma membrane regions (e.g., the lipid rafts) where horizontal molecular networks can represent input/output regions allowing the cell to have informational exchanges with the extracellular environment. Furthermore, some "pervasive signals" such as field potentials, pressure waves and thermal gradients that affect large parts of the brain cellular and molecular networks are discussed. Finally, at least two learning paradigms are analyzed taking into account the possible role of Volume Transmission: the so-called model of "temporal difference learning" and the "Turing B-unorganised machine". The relevance of this new view of brain organization for a deeper understanding of some neurophysiological and neuropathological aspects of its function is briefly discussed.

Fallon, Nevada FORGE Thermal-Hydrological-Mechanical Models

DOE Office of Scientific and Technical Information (OSTI.GOV)

Blankenship, Doug; Sonnenthal, Eric

Archive contains thermal-mechanical simulation input/output files. Included are files which fall into the following categories: ( 1 ) Spreadsheets with various input parameter calculations ( 2 ) Final Simulation Inputs ( 3 ) Native-State Thermal-Hydrological Model Input File Folders ( 4 ) Native-State Thermal-Hydrological-Mechanical Model Input Files ( 5 ) THM Model Stimulation Cases See 'File Descriptions.xlsx' resource below for additional information on individual files.

Lunar Solar Origins Exploration (LunaSOX)

NASA Technical Reports Server (NTRS)

Cooper, John F.; King, Joseph H.; Papitashvili, Natasha; Lipatov, Alexander S.; Sittler, Edward C.; Hartle, Richard E.

2011-01-01

The Moon offers a unique vantage point from which to investigate the Sun and its interaction via the solar wind magnetic fields, plasma, and energetic particles with the geospace system including the Moon itself. The lunar surface and exosphere provide in part a record of solar coronal plasma material input and resultant space weathering over billions of years. The structure and dynamics of solar wind interactions with the Moon provide an accessible near-Earth laboratory environment for study of general solar wind interactions with the vast multitude of airless asteroidal bodies of the inner solar system. Spacecraft in lunar orbit have the often simultaneous opportunity, except when in the Earth's magnetosphere, to make in-situ compositional measurements of the solar wind plasma and to carry out remote observations from the Moon of the solar corona, potentially enabled by lunar limb occultation of the solar disk. The LunaSOX project at NASA Goddard Space Flight Center is addressing these heliophysical science objectives from and of the Moon with support from NASA's Lunar Advanced Science and Exploration Research (LASER) program: (1) specify history of solar wind parameters at and sunward of the Moon through enhanced access (http://lunasox.gsfc.nasa.gov/) to legacy and operational mission data products from the Apollo era to the present, (2) model field and plasma interactions with the lunar surface, exosphere, and wake, as constrained by the available data, through hybrid kinetic code simulations, and (3) advance mission concepts for heliophysics from and of the Moon.

Correlation of Tumor Immunohistochemistry with Dynamic Contrast-Enhanced and DSC-MRI Parameters in Patients with Gliomas.

PubMed

Nguyen, T B; Cron, G O; Bezzina, K; Perdrizet, K; Torres, C H; Chakraborty, S; Woulfe, J; Jansen, G H; Thornhill, R E; Zanette, B; Cameron, I G

2016-12-01

Tumor CBV is a prognostic and predictive marker for patients with gliomas. Tumor CBV can be measured noninvasively with different MR imaging techniques; however, it is not clear which of these techniques most closely reflects histologically-measured tumor CBV. Our aim was to investigate the correlations between dynamic contrast-enhanced and DSC-MR imaging parameters and immunohistochemistry in patients with gliomas. Forty-three patients with a new diagnosis of glioma underwent a preoperative MR imaging examination with dynamic contrast-enhanced and DSC sequences. Unnormalized and normalized cerebral blood volume was obtained from DSC MR imaging. Two sets of plasma volume and volume transfer constant maps were obtained from dynamic contrast-enhanced MR imaging. Plasma volume obtained from the phase-derived vascular input function and bookend T1 mapping (Vp_Φ) and volume transfer constant obtained from phase-derived vascular input function and bookend T1 mapping (K trans _Φ) were determined. Plasma volume obtained from magnitude-derived vascular input function (Vp_SI) and volume transfer constant obtained from magnitude-derived vascular input function (K trans _SI) were acquired, without T1 mapping. Using CD34 staining, we measured microvessel density and microvessel area within 3 representative areas of the resected tumor specimen. The Mann-Whitney U test was used to test for differences according to grade and degree of enhancement. The Spearman correlation was performed to determine the relationship between dynamic contrast-enhanced and DSC parameters and histopathologic measurements. Microvessel area, microvessel density, dynamic contrast-enhanced, and DSC-MR imaging parameters varied according to the grade and degree of enhancement (P < .05). A strong correlation was found between microvessel area and Vp_Φ and between microvessel area and unnormalized blood volume (r s ≥ 0.61). A moderate correlation was found between microvessel area and normalized blood volume, microvessel area and Vp_SI, microvessel area and K trans _Φ, microvessel area and K trans _SI, microvessel density and Vp_Φ, microvessel density and unnormalized blood volume, and microvessel density and normalized blood volume (0.44 ≤ r s ≤ 0.57). A weaker correlation was found between microvessel density and K trans _Φ and between microvessel density and K trans _SI (r s ≤ 0.41). With dynamic contrast-enhanced MR imaging, use of a phase-derived vascular input function and bookend T1 mapping improves the correlation between immunohistochemistry and plasma volume, but not between immunohistochemistry and the volume transfer constant. With DSC-MR imaging, normalization of tumor CBV could decrease the correlation with microvessel area. © 2016 by American Journal of Neuroradiology.

Computational hydrodynamics and optical performance of inductively-coupled plasma adaptive lenses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mortazavi, M.; Urzay, J., E-mail: jurzay@stanford.edu; Mani, A.

2015-06-15

This study addresses the optical performance of a plasma adaptive lens for aero-optical applications by using both axisymmetric and three-dimensional numerical simulations. Plasma adaptive lenses are based on the effects of free electrons on the phase velocity of incident light, which, in theory, can be used as a phase-conjugation mechanism. A closed cylindrical chamber filled with Argon plasma is used as a model lens into which a beam of light is launched. The plasma is sustained by applying a radio-frequency electric current through a coil that envelops the chamber. Four different operating conditions, ranging from low to high powers andmore » induction frequencies, are employed in the simulations. The numerical simulations reveal complex hydrodynamic phenomena related to buoyant and electromagnetic laminar transport, which generate, respectively, large recirculating cells and wall-normal compression stresses in the form of local stagnation-point flows. In the axisymmetric simulations, the plasma motion is coupled with near-wall axial striations in the electron-density field, some of which propagate in the form of low-frequency traveling disturbances adjacent to vortical quadrupoles that are reminiscent of Taylor-Görtler flow structures in centrifugally unstable flows. Although the refractive-index fields obtained from axisymmetric simulations lead to smooth beam wavefronts, they are found to be unstable to azimuthal disturbances in three of the four three-dimensional cases considered. The azimuthal striations are optically detrimental, since they produce high-order angular aberrations that account for most of the beam wavefront error. A fourth case is computed at high input power and high induction frequency, which displays the best optical properties among all the three-dimensional simulations considered. In particular, the increase in induction frequency prevents local thermalization and leads to an axisymmetric distribution of electrons even after introduction of spatial disturbances. The results highlight the importance of accounting for spatial effects in the numerical computations when optical analyses of plasma lenses are pursued in this range of operating conditions.« less

Scintillation Observations and Response of The Ionosphere to Electrodynamics (SORTIE)

NASA Astrophysics Data System (ADS)

Crowley, G.

2015-12-01

The Scintillation Observations and Response of The Ionosphere to Electrodynamics, or SORTIE, mission is a 6U NASA Heliophysics CubeSat designed to study the ionosphere at altitudes below 400km. The SORTIE mission is being developed by a team including ASTRA (lead institution), AFRL, University of Texas at Dallas (UTD), COSMIAC (Satellite Integrator), and Boston College. SORTIE will address cutting-edge science in the area of ionospheric dynamics. The SORTIE mission will address the following science questions: Q1) Discover the sources of wave-like plasma perturbations in the F-region ionosphere. Q2) Determine the relative role of dynamo action and more direct mechanical forcing in the formation of wave-like plasma perturbations. To address these questions we plan to fly a CubeSat with novel sensors that measure key plasma parameters in a circular, low to middle inclination orbit near 350-400 km altitude. The sensors include an ion velocity meter (built by UTD) and a Planar Langmuir Probe (built by AFRL). The SORTIE mission plan is to describe the distribution of wave-like structures in the plasma density of the ionospheric F-region. In doing so, the SORTIE team will determine the possible role of these perturbations in aiding the growth of plasma instabilities. SORTIE will provide (1) the initial spectrum of wave perturbations which are the starting point for the RT calculation; (2) measured electric fields which determine the magnitude of the instability growth rate near the region where plasma bubbles are generated; (3) initial observations of irregularities in plasma density which result from RT growth. SORTIE results will be used as input to PBMOD, an assimilative first-principles physical model of the ionosphere, in order to predict evolution of EPBs. In this presentation, we will review the science objectives, provide an overview of the spacecraft and instrument design, and present a concept of operations plan.

SRC-2 orchestrates polygenic inputs for fine-tuning glucose homeostasis

PubMed Central

Fleet, Tiffany; Zhang, Bin; Lin, Fumin; Zhu, Bokai; Dasgupta, Subhamoy; Stashi, Erin; Tackett, Bryan; Thevananther, Sundararajah; Rajapakshe, Kimal I.; Gonzales, Naomi; Dean, Adam; Mao, Jianqiang; Timchenko, Nikolai; Malovannaya, Anna; Qin, Jun; Coarfa, Cristian; DeMayo, Francesco; Dacso, Clifford C.; Foulds, Charles E.; O’Malley, Bert W.; York, Brian

2015-01-01

Despite extensive efforts to understand the monogenic contributions to perturbed glucose homeostasis, the complexity of genetic events that fractionally contribute to the spectrum of this pathology remain poorly understood. Proper maintenance of glucose homeostasis is the central feature of a constellation of comorbidities that define the metabolic syndrome. The ability of the liver to balance carbohydrate uptake and release during the feeding-to-fasting transition is essential to the regulation of peripheral glucose availability. The liver coordinates the expression of gene programs that control glucose absorption, storage, and secretion. Herein, we demonstrate that Steroid Receptor Coactivator 2 (SRC-2) orchestrates a hierarchy of nutritionally responsive transcriptional complexes to precisely modulate plasma glucose availability. Using DNA pull-down technology coupled with mass spectrometry, we have identified SRC-2 as an indispensable integrator of transcriptional complexes that control the rate-limiting steps of hepatic glucose release and accretion. Collectively, these findings position SRC-2 as a major regulator of polygenic inputs to metabolic gene regulation and perhaps identify a previously unappreciated model that helps to explain the clinical spectrum of glucose dysregulation. PMID:26487680

An adaptive drug delivery design using neural networks for effective treatment of infectious diseases: a simulation study.

PubMed

Padhi, Radhakant; Bhardhwaj, Jayender R

2009-06-01

An adaptive drug delivery design is presented in this paper using neural networks for effective treatment of infectious diseases. The generic mathematical model used describes the coupled evolution of concentration of pathogens, plasma cells, antibodies and a numerical value that indicates the relative characteristic of a damaged organ due to the disease under the influence of external drugs. From a system theoretic point of view, the external drugs can be interpreted as control inputs, which can be designed based on control theoretic concepts. In this study, assuming a set of nominal parameters in the mathematical model, first a nonlinear controller (drug administration) is designed based on the principle of dynamic inversion. This nominal drug administration plan was found to be effective in curing "nominal model patients" (patients whose immunological dynamics conform to the mathematical model used for the control design exactly. However, it was found to be ineffective in curing "realistic model patients" (patients whose immunological dynamics may have off-nominal parameter values and possibly unwanted inputs) in general. Hence, to make the drug delivery dosage design more effective for realistic model patients, a model-following adaptive control design is carried out next by taking the help of neural networks, that are trained online. Simulation studies indicate that the adaptive controller proposed in this paper holds promise in killing the invading pathogens and healing the damaged organ even in the presence of parameter uncertainties and continued pathogen attack. Note that the computational requirements for computing the control are very minimal and all associated computations (including the training of neural networks) can be carried out online. However it assumes that the required diagnosis process can be carried out at a sufficient faster rate so that all the states are available for control computation.

Hot ion plasma production in HIP-1 using water-cooled hollow cathodes

NASA Technical Reports Server (NTRS)

Reinmann, J. J.; Lauver, M. R.; Patch, R. W.; Layman, R. W.; Snyder, A.

1975-01-01

A steady-state ExB plasma was formed by applying a strong radially inward dc electric field near the mirror throats. Most of the results were for hydrogen, but deuterium and helium plasmas were also studied. Three water-cooled hollow cathodes were operated in the hot-ion plasma mode with the following results: (1) thermally emitting cathodes were not required to achieve the hot-ion mode; (2) steady-state operation (several minutes) was attained; (3) input powers greater than 40 kW were achieved; (4) cathode outside diameters were increased from 1.2 cm (uncooled) to 4.4 cm (water-cooled); (5) steady-state hydrogen plasma with ion temperatures from 185 to 770 eV and electron temperatures from 5 to 21 eV were produced. Scaling relations were empirically obtained for discharge current, ion temperature, electron temperature, and relative ion density as a function of hydrogen gas feed rate, magnetic field, and cathode voltage. Neutrons were produced from deuterium plasma, but it was not established whether thay came from the plasma volume or from the electrode surfaces.

Results from an 8 Joule RMF-FRC Plasma Translation Experiment for Space Propulsion

NASA Astrophysics Data System (ADS)

Hill, Carrie; Uchizono, Nolan; Holmes, Michael

2017-10-01

Field-Reversed Configuration (FRC) thrusters are attractive for advanced in-space propulsion technology as their projected performance, low specific mass, and propellant flexibility offer significant benefits over state-of-the art thrusters. A benchtop experiment to evaluate FRC thruster behavior using a Rotating Magnetic Field (RMF) formation method was constructed at the Air Force Research Laboratory. This experiment generated an RMF-FRC in a conical geometry and accelerated the plasma into a field-free drift region, using 8 J of input energy. Downstream plasma probes in a time-of-flight array measured the exhaust contents of the plasma plume. Results from this diagnostic demonstrated that the ejected mass and ion exit velocities fell short of the desired specific impulse and momentum. Two high-speed cameras were installed to diagnose the gross plasma behavior from two perspectives. Results from these images are presented here. These images show that the plasma generated in the formation region for several different operating conditions was highly non-uniform and did not form a stable closed-field topology that is expected from RMF-FRC plasmas.

Advances in understanding quiescent H-mode plasmas in DIII-Da)

NASA Astrophysics Data System (ADS)

Burrell, K. H.; West, W. P.; Doyle, E. J.; Austin, M. E.; Casper, T. A.; Gohil, P.; Greenfield, C. M.; Groebner, R. J.; Hyatt, A. W.; Jayakumar, R. J.; Kaplan, D. H.; Lao, L. L.; Leonard, A. W.; Makowski, M. A.; McKee, G. R.; Osborne, T. H.; Snyder, P. B.; Solomon, W. M.; Thomas, D. M.; Rhodes, T. L.; Strait, E. J.; Wade, M. R.; Wang, G.; Zeng, L.

2005-05-01

Recent QH-mode research on DIII-D [J. L. Luxon et al., Plasma Physics and Controlled Nuclear Fusion Research 1996 (International Atomic Energy Agency, Vienna, 1987), Vol. I, p. 159] has used the peeling-ballooning modes model of edge magnetohydrodynamic stability as a working hypothesis to organize the data; several predictions of this theory are consistent with the experimental results. Current ramping results indicate that QH modes operate near the edge current limit set by peeling modes. This operating point explains why QH mode is easier to get at lower plasma currents. Power scans have shown a saturation of edge pressure with increasing power input. This allows QH-mode plasmas to remain stable to edge localized modes (ELMs) to the highest powers used in DIII-D. At present, the mechanism for this saturation is unknown; if the edge harmonic oscillation (EHO) is playing a role here, the physics is not a simple amplitude dependence. The increase in edge stability with plasma triangularity predicted by the peeling-ballooning theory is consistent with the substantial improvement in pedestal pressure achieved by changing the plasma shape from a single null divertor to a high triangularity double null. Detailed ELITE calculations for the high triangularity plasmas have demonstrated that the plasma operating point is marginally stable to peeling-ballooning modes. Comparison of ELMing, coinjected and quiescent, counterinjected discharges with the same shape, current, toroidal field, electron density, and electron temperature indicates that the edge radial electric field or the edge toroidal rotation are also playing a role in edge stability. The EHO produces electron, main ion, and impurity particle transport at the plasma edge which is more rapid than that produced by ELMs under similar conditions. The EHO also decreases the edge rotation while producing little change in the edge electron and ion temperatures. Other edge electromagnetic modes also produce particle transport; this includes the incoherent, broadband activity seen at high triangularity. Pedestal values of ν* and βT bracketing, those required for International Experimental Thermonuclear Reactor [Nucl. Fusion 39, 2137 (1999)] have been achieved in DIII-D, demonstrating the QH-mode edge densities are sufficient for future devices.

Advances in understanding quiescent H-mode plasmas in DIII-D

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burrell, K.H.; West, W.P.; Gohil, P.

2005-05-15

Recent QH-mode research on DIII-D [J. L. Luxon et al., Plasma Physics and Controlled Nuclear Fusion Research 1996 (International Atomic Energy Agency, Vienna, 1987), Vol. I, p. 159] has used the peeling-ballooning modes model of edge magnetohydrodynamic stability as a working hypothesis to organize the data; several predictions of this theory are consistent with the experimental results. Current ramping results indicate that QH modes operate near the edge current limit set by peeling modes. This operating point explains why QH mode is easier to get at lower plasma currents. Power scans have shown a saturation of edge pressure with increasingmore » power input. This allows QH-mode plasmas to remain stable to edge localized modes (ELMs) to the highest powers used in DIII-D. At present, the mechanism for this saturation is unknown; if the edge harmonic oscillation (EHO) is playing a role here, the physics is not a simple amplitude dependence. The increase in edge stability with plasma triangularity predicted by the peeling-ballooning theory is consistent with the substantial improvement in pedestal pressure achieved by changing the plasma shape from a single null divertor to a high triangularity double null. Detailed ELITE calculations for the high triangularity plasmas have demonstrated that the plasma operating point is marginally stable to peeling-ballooning modes. Comparison of ELMing, coinjected and quiescent, counterinjected discharges with the same shape, current, toroidal field, electron density, and electron temperature indicates that the edge radial electric field or the edge toroidal rotation are also playing a role in edge stability. The EHO produces electron, main ion, and impurity particle transport at the plasma edge which is more rapid than that produced by ELMs under similar conditions. The EHO also decreases the edge rotation while producing little change in the edge electron and ion temperatures. Other edge electromagnetic modes also produce particle transport; this includes the incoherent, broadband activity seen at high triangularity. Pedestal values of {nu}{sub *} and {beta}{sub T} bracketing, those required for International Experimental Thermonuclear Reactor [Nucl. Fusion 39, 2137 (1999)] have been achieved in DIII-D, demonstrating the QH-mode edge densities are sufficient for future devices.« less

Battery-Powered RF Pre-Ionization System for the Caltech Magnetohydrodynamically-Driven Jet Experiment: RF Discharge Properties and MHD-Driven Jet Dynamics

NASA Astrophysics Data System (ADS)

Chaplin, Vernon H.

This thesis describes investigations of two classes of laboratory plasmas with rather different properties: partially ionized low pressure radiofrequency (RF) discharges, and fully ionized high density magnetohydrodynamically (MHD)-driven jets. An RF pre-ionization system was developed to enable neutral gas breakdown at lower pressures and create hotter, faster jets in the Caltech MHD-Driven Jet Experiment. The RF plasma source used a custom pulsed 3 kW 13.56 MHz RF power amplifier that was powered by AA batteries, allowing it to safely float at 4-6 kV with the cathode of the jet experiment. The argon RF discharge equilibrium and transport properties were analyzed, and novel jet dynamics were observed. Although the RF plasma source was conceived as a wave-heated helicon source, scaling measurements and numerical modeling showed that inductive coupling was the dominant energy input mechanism. A one-dimensional time-dependent fluid model was developed to quantitatively explain the expansion of the pre-ionized plasma into the jet experiment chamber. The plasma transitioned from an ionizing phase with depressed neutral emission to a recombining phase with enhanced emission during the course of the experiment, causing fast camera images to be a poor indicator of the density distribution. Under certain conditions, the total visible and infrared brightness and the downstream ion density both increased after the RF power was turned off. The time-dependent emission patterns were used for an indirect measurement of the neutral gas pressure. The low-mass jets formed with the aid of the pre-ionization system were extremely narrow and collimated near the electrodes, with peak density exceeding that of jets created without pre-ionization. The initial neutral gas distribution prior to plasma breakdown was found to be critical in determining the ultimate jet structure. The visible radius of the dense central jet column was several times narrower than the axial current channel radius, suggesting that the outer portion of the jet must have been force free, with the current parallel to the magnetic field. The studies of non-equilibrium flows and plasma self-organization being carried out at Caltech are relevant to astrophysical jets and fusion energy research.

Converting from Transdermal to Buccal Formulations of Buprenorphine: A Pharmacokinetic Meta-Model Simulation in Healthy Volunteers.

PubMed

Priestley, Tony; Chappa, Arvind K; Mould, Diane R; Upton, Richard N; Shusterman, Neil; Passik, Steven; Tormo, Vicente J; Camper, Stephen

2017-09-29

 To develop a model to predict buprenorphine plasma concentrations during transition from transdermal to buccal administration.  Population pharmacokinetic model-based meta-analysis of published data.  A model-based meta-analysis of available buprenorphine pharmacokinetic data in healthy adults, extracted as aggregate (mean) data from published literature, was performed to explore potential conversion from transdermal to buccal buprenorphine. The time course of mean buprenorphine plasma concentrations following application of transdermal patch or buccal film was digitized from available literature, and a meta-model was developed using specific pharmacokinetic parameters (e.g., absorption rate, apparent clearance, and volumes of distribution) derived from analysis of pharmacokinetic data for intravenously, transdermally, and buccally administered buprenorphine.  Data from six studies were included in this analysis. The final transdermal absorption model employed a zero-order input rate that was scaled to reflect a nominal patch delivery rate and time after patch application (with decline in rate over time). The transdermal absorption rate constant became zero following patch removal. Buccal absorption was a first-order process with a time lag and bioavailability term. Simulations of conversion from transdermal 20 mcg/h and 10 mcg/h to buccal administration suggest that transition can be made rapidly (beginning 12 hours after patch removal) using the recommended buccal formulation titration increments (75-150 mcg) and schedule (every four days) described in the product labeling.  Computer modeling and simulations using a meta-model built from data extracted from publications suggest that rapid and straightforward conversion from transdermal to buccal buprenorphine is feasible. © 2017 American Academy of Pain Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Improved Abutting Edges For Welding In Keyhole Mode

NASA Technical Reports Server (NTRS)

Harwing, Dennis D.; Sanders, John M.

1994-01-01

Welds of better quality made, and/or heat input reduced. Improved shapes devised for abutting edges of metal pieces to be joined by plasma arc welding in keyhole mode, in which gas jet maintains molten hole ("keyhole") completely through thickness of weld joint. Edges of metal pieces to be welded together machined to provide required combination gap and shaped, thin sections. Shapes and dimensions chosen to optimize weld in various respects; e.g., to enhance penetration of keyhole or reduce heat input to produce joint of given thickness.

Effect of turbulent flow on an atmospheric-pressure AC powered gliding arc discharge

NASA Astrophysics Data System (ADS)

Kong, Chengdong; Gao, Jinlong; Zhu, Jiajian; Ehn, Andreas; Aldén, Marcus; Li, Zhongshan

2018-06-01

A high-power gliding arc (GA) discharge was generated in a turbulent air flow driven by a 35 kHz alternating current electric power supply. The effects of the flow rate on the characteristics of the GA discharge were investigated using combined optical and electrical diagnostics. Phenomenologically, the GA discharge exhibits two types of discharge, i.e., glow type and spark type, depending on the flow rates and input powers. The glow-type discharge, which has peak currents of hundreds of milliamperes, is sustained at low flow rates. The spark-type discharge, which is characterized by a sharp current spike of several amperes with duration of less than 1 μs, occurs more frequently as the flow rate increases. Higher input power can suppress spark-type discharges in moderate turbulence, but this effect becomes weak under high turbulent conditions. Physically, the transition between glow- and spark-type is initiated by the short cutting events and the local re-ignition events. Short cutting events occur owing to the twisting, wrinkling, and stretching of the plasma columns that are governed by the relatively large vortexes in the flow. Local re-ignition events, which are defined as re-ignition along plasma columns, are detected in strong turbulence due to increment of the impedance of the plasma column and consequently the internal electric field strength. It is suggested that the vortexes with length scales smaller than the size of the plasma can penetrate into the plasma column and promote mixing with surroundings to accelerate the energy dissipation. Therefore, the turbulent flow influences the GA discharges by ruling the short cutting events with relatively large vortexes and the local re-ignition events with small vortexes.

Suppression of melatonin secretion in some blind patients by exposure to bright light.

PubMed

Czeisler, C A; Shanahan, T L; Klerman, E B; Martens, H; Brotman, D J; Emens, J S; Klein, T; Rizzo, J F

1995-01-05

Complete blindness generally results in the loss of synchronization of circadian rhythms to the 24-hour day and in recurrent insomnia. However, some blind patients maintain circadian entrainment. We undertook this study to determine whether some blind patients' eyes convey sufficient photic information to entrain the hypothalamic circadian pacemaker and suppress melatonin secretion, despite an apparently complete loss of visual function. We evaluated the input of light to the circadian pacemaker by testing the ability of bright light to decrease plasma melatonin concentrations in 11 blind patients with no conscious perception of light and in 6 normal subjects. We also evaluated circadian entrainment over time in the blind patients. Plasma melatonin concentrations decreased during exposure to bright light in three sightless patients by an average (+/- SD) of 69 +/- 21 percent and in the normal subjects by an average of 66 +/- 15 percent. When two of these blind patients were tested with their eyes covered during exposure to light, plasma melatonin did not decrease. The three blind patients reported no difficulty sleeping and maintained apparent circadian entrainment to the 24-hour day. Plasma melatonin concentrations did not decrease during exposure to bright light in seven of the remaining blind patients; in the eighth, plasma melatonin was undetectable. These eight patients reported a history of insomnia, and in four the circadian temperature rhythm was not entrained to the 24-hour day. The visual subsystem that mediates light-induced suppression of melatonin secretion remains functionally intact in some sightless patients. The absence of photic input to the circadian system thus constitutes a distinct form of blindness, associated with periodic insomnia, that afflicts most but not all patients with no conscious perception of light.

The National Transport Code Collaboration Module Library

NASA Astrophysics Data System (ADS)

Kritz, A. H.; Bateman, G.; Kinsey, J.; Pankin, A.; Onjun, T.; Redd, A.; McCune, D.; Ludescher, C.; Pletzer, A.; Andre, R.; Zakharov, L.; Lodestro, L.; Pearlstein, L. D.; Jong, R.; Houlberg, W.; Strand, P.; Wiley, J.; Valanju, P.; John, H. St.; Waltz, R.; Mandrekas, J.; Mau, T. K.; Carlsson, J.; Braams, B.

2004-12-01

This paper reports on the progress in developing a library of code modules under the auspices of the National Transport Code Collaboration (NTCC). Code modules are high quality, fully documented software packages with a clearly defined interface. The modules provide a variety of functions, such as implementing numerical physics models; performing ancillary functions such as I/O or graphics; or providing tools for dealing with common issues in scientific programming such as portability of Fortran codes. Researchers in the plasma community submit code modules, and a review procedure is followed to insure adherence to programming and documentation standards. The review process is designed to provide added confidence with regard to the use of the modules and to allow users and independent reviews to validate the claims of the modules' authors. All modules include source code; clear instructions for compilation of binaries on a variety of target architectures; and test cases with well-documented input and output. All the NTCC modules and ancillary information, such as current standards and documentation, are available from the NTCC Module Library Website http://w3.pppl.gov/NTCC. The goal of the project is to develop a resource of value to builders of integrated modeling codes and to plasma physics researchers generally. Currently, there are more than 40 modules in the module library.

Perturbative transport modeling and comparison to cold-pulse and heat-pulse propagation experiments in Alcator C-Mod and DIII-D

NASA Astrophysics Data System (ADS)

Rodriguez Fernandez, P.; White, A. E.; Cao, N. M.; Creely, A. J.; Greenwald, M. J.; Howard, N. T.; Hubbard, A. E.; Hughes, J. W.; Irby, J. H.; Petty, C. C.; Rice, J. E.; Alcator C-Mod Team

2016-10-01

Possible ``non-local'' transport phenomena are often observed in tokamak plasmas. Different models have been proposed to explain fast responses during perturbative transport experiments, including non-diffusive effects. Specific tools to characterize the dynamic behavior and power balance analysis using TRANSP and the quasi-linear trapped gyro-landau fluid code TGLF have been developed to analyze Alcator C-Mod experiments. Recent results from cold pulse experiments show that fast core temperature increases following edge cold-pulse injections (peak within 10ms , while τE 25ms) are not correlated with the direction of intrinsic rotation, and instead the amplitude of the core response depends on density, plasma current and RF input power. The propagation of the cold pulse can be compared with propagation of heat pulses from sawteeth, and both may be used to probe changes in temperature profile stiffness. A Laser Blow Off (LBO) system is being developed for DIII-D that will allow further validation and cross-machine comparison of cold pulse experiments. LBO at DIII-D will also allow for direct comparisons with ECH perturbative heat pulse experiments. Work supported by US DOE under Grants DE-FC02-99ER54512 (C-Mod) and DE-FC02-04ER54698 (DIII-D) and La Caixa Fellowship.

O+ trough zones in the polar cap ionosphere-magnetosphere coupling region

NASA Astrophysics Data System (ADS)

Horwitz, James; Zeng, Wen; Jaafari, Fajer

Regions of low-density troughs in O+ have been observed at 1 RE altitude in the polar cap ionosphere-magnetosphere region by the Thermal Ion Dynamics Experiment(TIDE) on the POLAR spacecraft. In this presentation, the UT Arlington Dynamic Fluid-Kinetic (DyFK) code is employed to investigate the formation of such O+ density troughs. We utilize convection paths of flux tubes in the high-latitude region as prescribed by an empirical convection model with solar wind inputs to track the evolution of ionospheric plasma transport and in particular O+ densities along these tubes with time/space. The flux tubes are subjected to auroral processes of precipitation and wave-driven ion heating when they pass through the auroral oval, which tends to elevate the plasma densities in these tubes. When the F-regions of such tubes traverse locations where the F-region is in darkness, recombination there causes the higher-altitude regions to drain and the densities to decline throughout. Owing to the varying effects of these processes, significant and low trough-like densities at higher altitudes developed along these flux tubes. The modeled densities near 6000 km altitudes will be compared with multiple POLAR passes featuring POLAR/TIDE-measured O+ densities for inside and outside of such trough regions.

Strategies for the generation of parametric images of [11C]PIB with plasma input functions considering discriminations and reproducibility.

PubMed

Edison, Paul; Brooks, David J; Turkheimer, Federico E; Archer, Hilary A; Hinz, Rainer

2009-11-01

Pittsburgh compound B or [11C]PIB is an amyloid imaging agent which shows a clear differentiation between subjects with Alzheimer's disease (AD) and controls. However the observed signal difference in other forms of dementia such as dementia with Lewy bodies (DLB) is smaller, and mild cognitively impaired (MCI) subjects and some healthy elderly normals may show intermediate levels of [11C]PIB binding. The cerebellum, a commonly used reference region for non-specific tracer uptake in [11C]PIB studies in AD may not be valid in Prion disorders or monogenic forms of AD. The aim of this work was to: 1-compare methods for generating parametric maps of [11C]PIB retention in tissue using a plasma input function in respect of their ability to discriminate between AD subjects and controls and 2-estimate the test-retest reproducibility in AD subjects. 12 AD subjects (5 of which underwent a repeat scan within 6 weeks) and 10 control subjects had 90 minute [11C]PIB dynamic PET scans, and arterial plasma input functions were measured. Parametric maps were generated with graphical analysis of reversible binding (Logan plot), irreversible binding (Patlak plot), and spectral analysis. Between group differentiation was calculated using Student's t-test and comparisons between different methods were made using p values. Reproducibility was assessed by intraclass correlation coefficients (ICC). We found that the 75 min value of the impulse response function showed the best group differentiation and had a higher ICC than volume of distribution maps generated from Logan and spectral analysis. Patlak analysis of [11C]PIB binding was the least reproducible.

The reaction of chlorobenzene with plasma of H2O, CO2 and CH4 obtained by an alternating-current plasma torch with a vortex stabilization

NASA Astrophysics Data System (ADS)

Surov, A. V.; Subbotin, D. I.; Obraztsov, N. V.; Popov, S. D.; Popov, V. E.; Litvyakova, A. I.; Pavlov, A. V.; Serba, E. O.; Spodobin, V. A.; Nakonechny, Gh V.

2018-01-01

This paper presents the three-phase ac plasma torch with a vortex stabilization of the arc, and two inputs of plasma environments: the electrode zone and the arc zone. Shielding gas (carbon dioxide) is supplied in the electrode zone and steam, methane and vapor of chlorobenzene are fed in the arc zone. By means of it the life time of electrodes is increased significantly. Chlorobenzene is selected, as it is the simplest aromatic chlorine-containing substance. The chemical process flows in two pathways: the formation of synthesis gas and the formation of soot. The gaseous chlorine-containing compound was only hydrogen chloride, yield of soot was 0.98% by weight of the raw materials, and the chlorine content was 2.08 wt% by the soot.

Plasma Propulsion Testing Capabilities at Arnold Engineering Development Center

NASA Technical Reports Server (NTRS)

Polzin, Kurt A.; Dawbarn, Albert; Moeller, Trevor

2007-01-01

This paper describes the results of a series of experiments aimed at quantifying the plasma propulsion testing capabilities of a 12-ft diameter vacuum facility (12V) at USAF-Arnold Engineering Development Center (AEDC). Vacuum is maintained in the 12V facility by cryogenic panels lining the interior of the chamber. The pumping capability of these panels was shown to be great enough to support plasma thrusters operating at input electrical power >20 kW. In addition, a series of plasma diagnostics inside the chamber allowed for measurement of plasma parameters at different spatial locations, providing information regarding the chamber's effect on the global plasma thruster flowfield. The plasma source used in this experiment was Hall thruster manufactured by Busek Co. The thruster was operated at up to 20 kW steady-state power in both a lower current and higher current mode. The vacuum level in the chamber never rose above 9 x 10(exp -6) torr during the course of testing. Langmuir probes, ion flux probes, and Faraday cups were used to quantify the plasma parameters in the chamber. We present the results of these measurements and estimates of pumping speed based on the background pressure level and thruster propellant mass flow rate.

Implementation of ERDC HEP Geo-Material Model in CTH and Application

DTIC Science & Technology

2011-11-02

used TARDEC JWL inputs for C4 and Johnson- Cook Strength inputs   TARDEC JC fracture model inputs for 5083 plate changed due to problems seen in...fracture inputs from IMD tests -  LS-DYNA C4 JWL and Johnson-Cook strength inputs used in CTH runs -  Results indicate that TARDEC JC fracture model

Application of a Dielectric Barrier Discharge Atmospheric Cold Plasma (Dbd-Acp) for Eshcerichia Coli Inactivation in Apple Juice.

PubMed

Liao, Xinyu; Li, Jiao; Muhammad, Aliyu Idris; Suo, Yuanjie; Chen, Shiguo; Ye, Xingqian; Liu, Donghong; Ding, Tian

2018-02-01

Atmospheric cold plasma (ACP) is a promising non-thermal technology in food industry. In this study, a dielectric barrier discharge (DBD)-ACP exhibited strong bactericidal effect on Escherichia coli in apple juice. Under a 30 to 50 W input power, less than 40 s treatment time was required for DBD-ACP to result in 3.98 to 4.34 log CFU/mL reduction of E. coli in apple juice. The inactivation behavior of ACP on E. coli was well described by the Weibull model. During the treatment, the cell membrane of E. coli was damaged severely by active species produced by plasma, such as hydrogen peroxide, ozone and nitrate. In addition, the ACP exposure had slight effect on the °Brix, pH, titratable acidity (TA), color values, total phenolic content, and antioxidant capacity of apple juice. However, higher level of DBD-ACP treatment, 50 W for more than 10 s in this case, resulted in significant change of the pH, TA, color and total phenolic content of apple juice. The results in this study have provided insight in potential use of DBD-ACP as an alternative to thermal processing for fruit juices in food industry. Escherichia coli O157:H7 in apple juice is a potential risk for public health. This study demonstrated that 30 s cold plasma treatment resulted in more than 4 log CFU/mL reduction under 50 W, while the quality attributes of apple juice were not significantly affected. Therefore, cold plasma technology is a promising alternative substitute of traditional thermal processing for juice pasteurization. © 2018 Institute of Food Technologists®.

Near Real Time Tools for ISS Plasma Science and Engineering Applications

NASA Astrophysics Data System (ADS)

Minow, J. I.; Willis, E. M.; Parker, L. N.; Shim, J.; Kuznetsova, M. M.; Pulkkinen, A. A.

2013-12-01

The International Space Station (ISS) program utilizes a plasma environment forecast for estimating electrical charging hazards for crews during extravehicular activity (EVA). The process uses ionospheric electron density and temperature measurements from the ISS Floating Potential Measurement Unit (FPMU) instrument suite with the assumption that the plasma conditions will remain constant for one to fourteen days with a low probability for a space weather event which would significantly change the environment before an EVA. FPMU data is typically not available during EVA's, therefore, the most recent FPMU data available for characterizing the state of the ionosphere during EVA is typically a day or two before the start of an EVA or after the EVA has been completed. In addition to EVA support, information on ionospheric plasma densities is often needed for support of ISS science payloads and anomaly investigations during periods when the FPMU is not operating. This presentation describes the application of space weather tools developed by MSFC using data from near real time satellite radio occultation and ground based ionosonde measurements of ionospheric electron density and a first principle ionosphere model providing electron density and temperature run in a real time mode by GSFC. These applications are used to characterize the space environment during EVA periods when FPMU data is not available, monitor for large charges in ionosphere density that could render the ionosphere forecast and plasma hazard assessment invalid, and validate the assumption of 'persistence of conditions' used in deriving the hazard forecast. In addition, the tools are used to provide space environment input to science payloads on ISS and anomaly investigations during periods the FPMU is not operating.

Compact Ultraintense Femtosecond Laser via Raman Amplifier and Compressor in Plasma

DOE Office of Scientific and Technical Information (OSTI.GOV)

Suckewer, Szymon

2016-03-01

The main objective of this project was to conduct experimental and theoretical research to find conditions leading to higher, than previously obtained efficiency η of transfer the pump energy into the short seed beam in plasma of Stimulated Raman Back-Scattering (SRBS). We have demonstrated very large amplification and compression in our earlier SRBS plasma. However, the efficiency η was much too low to reach very high intensity of the output beam in the focal spot. Recently, by solving a very difficult technical SRBS’ problem, namely, the creation of very reproducible and much larger diameter plasma channels than in our earliermore » research, we propose a new approach to obtain higher efficiency η. The crucial new result was a very reproducible, low noise amplified seed in the larger diameter of the plasma channel leading to the higher efficiency. Using this new setup and very encouraging results about increase efficiency continuing this approach in the future the efficiency is expect to reach the range of η ≈15 - 20 % required to develop practical SRBS plasma laser. Intellectual Merit: The model for the present project was created by our earlier SRBS experiments. The main objective of those experiments was to amplify and compress the seed pulses in a plasma . The experiments demonstrated an unprecedented large pulse intensity amplification of 20,000 in system of 2-passes in ~2mm long plasma, and the seed pulse compression from 550fsec down to ~50fsec. The pump and seed beams in the present project have diameters of ~0.2–0.25mm each, propagating in ~0.35 - 0.45mm diameter and ~2-2.5mm long plasma channels (optimal length for our SRBS experiment) with input pump and seed intensities of 2x1014 and 3x1013 W/cm2, respectively. Such an SRBS system design was “prescribed” by computer simulations, which predict elimination of the SRBS “ saturation” for a such relatively short plasma channel. Plasma channels has been created by combining shorter (200psec) and longer (5nsec) laser pulses using an axicon lens for shorter pulse and spherical lens for longer pulse, a unique procedure we have developed for SRBS experiments.« less

Input variable selection for data-driven models of Coriolis flowmeters for two-phase flow measurement

NASA Astrophysics Data System (ADS)

Wang, Lijuan; Yan, Yong; Wang, Xue; Wang, Tao

2017-03-01

Input variable selection is an essential step in the development of data-driven models for environmental, biological and industrial applications. Through input variable selection to eliminate the irrelevant or redundant variables, a suitable subset of variables is identified as the input of a model. Meanwhile, through input variable selection the complexity of the model structure is simplified and the computational efficiency is improved. This paper describes the procedures of the input variable selection for the data-driven models for the measurement of liquid mass flowrate and gas volume fraction under two-phase flow conditions using Coriolis flowmeters. Three advanced input variable selection methods, including partial mutual information (PMI), genetic algorithm-artificial neural network (GA-ANN) and tree-based iterative input selection (IIS) are applied in this study. Typical data-driven models incorporating support vector machine (SVM) are established individually based on the input candidates resulting from the selection methods. The validity of the selection outcomes is assessed through an output performance comparison of the SVM based data-driven models and sensitivity analysis. The validation and analysis results suggest that the input variables selected from the PMI algorithm provide more effective information for the models to measure liquid mass flowrate while the IIS algorithm provides a fewer but more effective variables for the models to predict gas volume fraction.

A tracer kinetic model for 18F-FHBG for quantitating herpes simplex virus type 1 thymidine kinase reporter gene expression in living animals using PET.

PubMed

Green, Leeta Alison; Nguyen, Khoi; Berenji, Bijan; Iyer, Meera; Bauer, Eileen; Barrio, Jorge R; Namavari, Mohammad; Satyamurthy, Nagichettiar; Gambhir, Sanjiv S

2004-09-01

Reporter probe 9-(4-18F-fluoro-3-[hydroxymethyl]butyl)guanine (18F-FHBG) and reporter gene mutant herpes simplex virus type 1 thymidine kinase (HSV1-sr39tk) have been used for imaging reporter gene expression with PET. Current methods for quantitating the images using the percentage injected dose per gram of tissue do not distinguish between the effects of probe transport and subsequent phosphorylation. We therefore investigated tracer kinetic models for 18F-FHBG dynamic microPET data and noninvasive methods for determining blood time-activity curves in an adenoviral gene delivery model in mice. 18F-FHBG (approximately 7.4 MBq [approximately 200 microCi]) was injected into 4 mice; 18F-FHBG concentrations in plasma and whole blood were measured from mouse heart left ventricle (LV) direct sampling. Replication-incompetent adenovirus (0-2 x 10(9) plaque-forming units) with the E1 region deleted (n = 8) or replaced by HSV1-sr39tk (n = 18) was tail-vein injected into mice. Mice were dynamically scanned using microPET (approximately 7.4 MBq [approximately 200 microCi] 18F-FHBG) over 1 h; regions of interest were drawn on images of the heart and liver. Serial whole blood 18F-FHBG concentrations were measured in 6 of the mice by LV sampling, and 1 least-squares ratio of the heart image to the LV time-activity curve was calculated for all 6 mice. For 2 control mice and 9 mice expressing HSV1-sr39tk, heart image (input function) and liver image time-activity curves (tissue curves) were fit to 2- and 3-compartment models using Levenberg-Marquardt nonlinear regression. The models were compared using an F statistic. HSV1-sr39TK enzyme activity was determined from liver samples and compared with model parameter estimates. For another 3 control mice and 6 HSV1-sr39TK-positive mice, the model-predicted relative percentage of metabolites was compared with high-performance liquid chromatography analysis. The ratio of 18F-FHBG in plasma to whole blood was 0.84 +/- 0.05 (mean +/- SE) by 30 s after injection. The least-squares ratio of the heart image time-activity curve to the LV time-activity curve was 0.83 +/- 0.02, consistent with the recovery coefficient for the partial-volume effect (0.81) based on independent measures of heart geometry. A 3-compartment model best described 18F-FHBG kinetics in mice expressing HSV1-sr39tk in the liver; a 2-compartment model best described the kinetics in control mice. The 3-compartment model parameter, k3, correlated well with the HSV1-sr39TK enzyme activity (r2 = 0.88). 18F-FHBG equilibrates rapidly between plasma and whole blood in mice. Heart image time-activity curves corrected for partial-volume effects well approximate LV time-activity curves and can be used as input functions for 2- and 3-compartment models. The model parameter k3 from the 3-compartment model can be used as a noninvasive estimate for HSV1-sr39TK reporter protein activity and can predict the relative percentage of metabolites.

Solute solver 'what if' module for modeling urea kinetics.

PubMed

Daugirdas, John T

2016-11-01

The publicly available Solute Solver module allows calculation of a variety of two-pool urea kinetic measures of dialysis adequacy using pre- and postdialysis plasma urea and estimated dialyzer clearance or estimated urea distribution volumes as inputs. However, the existing program does not have a 'what if' module, which would estimate the plasma urea values as well as commonly used measures of hemodialysis adequacy for a patient with a given urea distribution volume and urea nitrogen generation rate dialyzed according to a particular dialysis schedule. Conventional variable extracellular volume 2-pool urea kinetic equations were used. A javascript-HTML Web form was created that can be used on any personal computer equipped with internet browsing software, to compute commonly used Kt/V-based measures of hemodialysis adequacy for patients with differing amounts of residual kidney function and following a variety of treatment schedules. The completed Web form calculator may be particularly useful in computing equivalent continuous clearances for incremental hemodialysis strategies. © The Author 2016. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.

Energy transport and dynamics

NASA Technical Reports Server (NTRS)

Schmieder, Brigitte; Peres, Giovanni; Enome, Shinzo; Falciani, Roberto; Heinzel, Petr; Henoux, Jean-Claude; Mariska, John T.; Reale, Fabio; Rilee, Mike L.; Rompolt, Bogdan

1994-01-01

We report findings concerning energy transport and dynamics in flares during the impulsive and gradual phases based on new ground-based and space observations (notably from Yohkoh). A preheating sometimes occurs during the impulsive phase. Ca XIX line shifts are confirmed to be good tracers of bulk plasma motions, although strong blue shifts are not as frequent as previously claimed. They often appear correlated with hard X-rays but, for some events, the concept that electron beams provide the whole energy input to the thermal component seems not to apply. Theory now yields: new diagnostics of low-energy proton and electric beams; accurate hydrodynamical modeling of pulse beam heating of the atmosphere; possible diagnostics of microflares (based on X-ray line ratio or on loop variability); and simulated images of chromospheric evaporation fronts. For the gradual phase, the continual reorganization of magnetic field lines over active regions determines where and when magnetic reconnection, the mechanism favored for energy release, will occur. Spatial and temporal fragmentation of the energy release, observed at different wavelengths, is considered to be a factor as well in energy transport and plasma dynamics.

Tail reconnection in the global magnetospheric context: Vlasiator first results

NASA Astrophysics Data System (ADS)

Palmroth, Minna; Hoilijoki, Sanni; Juusola, Liisa; Pulkkinen, Tuija I.; Hietala, Heli; Pfau-Kempf, Yann; Ganse, Urs; von Alfthan, Sebastian; Vainio, Rami; Hesse, Michael

2017-11-01

The key dynamics of the magnetotail have been researched for decades and have been associated with either three-dimensional (3-D) plasma instabilities and/or magnetic reconnection. We apply a global hybrid-Vlasov code, Vlasiator, to simulate reconnection self-consistently in the ion kinetic scales in the noon-midnight meridional plane, including both dayside and nightside reconnection regions within the same simulation box. Our simulation represents a numerical experiment, which turns off the 3-D instabilities but models ion-scale reconnection physically accurately in 2-D. We demonstrate that many known tail dynamics are present in the simulation without a full description of 3-D instabilities or without the detailed description of the electrons. While multiple reconnection sites can coexist in the plasma sheet, one reconnection point can start a global reconfiguration process, in which magnetic field lines become detached and a plasmoid is released. As the simulation run features temporally steady solar wind input, this global reconfiguration is not associated with sudden changes in the solar wind. Further, we show that lobe density variations originating from dayside reconnection may play an important role in stabilising tail reconnection.

In Vivo Quantification of Human Serotonin 1A Receptor Using 11C-CUMI-101, an Agonist PET Radiotracer

PubMed Central

Milak, Matthew S.; DeLorenzo, Christine; Zanderigo, Francesca; Prabhakaran, Jaya; Kumar, J.S. Dileep; Majo, Vattoly J.; Mann, J. John; Parsey, Ramin V.

2013-01-01

The serotonin (5-hydroxytryptamine, or 5-HT) type 1A receptor (5-HT1AR) is implicated in the pathophysiology of numerous neuropsychiatric disorders. We have published the initial evaluation and reproducibility in vivo of [O-methyl-11C]2-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-4-methyl-1,2,4-triazine-3,5 (2H,4H)dione (11C-CUMI-101), a novel 5-HT1A agonist radiotracer, in Papio anubis. Here, we report the optimal modeling parameters of 11C-CUMI-101 for human PET studies. Methods PET scans were obtained for 7 adult human volunteers. 11C-CUMI-101 was injected as an intravenous bolus, and emission data were collected for 120 min in 3-dimensional mode. We evaluated 10 different models using metabolite-corrected arterial input functions or reference region approaches and several outcome measures. Results When using binding potential (BPF = Bavail/KD [total available receptor concentration divided by the equilibrium dissociation constant]) as the outcome measure, the likelihood estimation in the graphical analysis (LEGA) model performed slightly better than the other methods evaluated at full scan duration. The average test–retest percentage difference was 9.90% ± 5.60%. When using BPND (BPND = fnd × Bavail/KD; BPND equals the product of BPF and fnd [free fraction in the nondisplaceable compartment]), the simplified reference tissue method (SRTM) achieved the lowest percentage difference and smallest bias when compared with nondisplaceable binding potential obtained from LEGA using the metabolite-corrected plasma input function (r2 = 0.99; slope = 0.92). The time–stability analysis indicates that a 120-min scan is sufficient for the stable estimation of outcome measures. Voxel results were comparable to region-of-interest–based analysis, with higher spatial resolution. Conclusion On the basis of its measurable and stable free fraction, high affinity and selectivity, good blood–brain barrier permeability, and plasma and brain kinetics, 11C-CUMI-101 is suitable for the imaging of high-affinity 5-HT1A binding in humans. PMID:21098796

Experimental benchmark of the NINJA code for application to the Linac4 H- ion source plasma

NASA Astrophysics Data System (ADS)

Briefi, S.; Mattei, S.; Rauner, D.; Lettry, J.; Tran, M. Q.; Fantz, U.

2017-10-01

For a dedicated performance optimization of negative hydrogen ion sources applied at particle accelerators, a detailed assessment of the plasma processes is required. Due to the compact design of these sources, diagnostic access is typically limited to optical emission spectroscopy yielding only line-of-sight integrated results. In order to allow for a spatially resolved investigation, the electromagnetic particle-in-cell Monte Carlo collision code NINJA has been developed for the Linac4 ion source at CERN. This code considers the RF field generated by the ICP coil as well as the external static magnetic fields and calculates self-consistently the resulting discharge properties. NINJA is benchmarked at the diagnostically well accessible lab experiment CHARLIE (Concept studies for Helicon Assisted RF Low pressure Ion sourcEs) at varying RF power and gas pressure. A good general agreement is observed between experiment and simulation although the simulated electron density trends for varying pressure and power as well as the absolute electron temperature values deviate slightly from the measured ones. This can be explained by the assumption of strong inductive coupling in NINJA, whereas the CHARLIE discharges show the characteristics of loosely coupled plasmas. For the Linac4 plasma, this assumption is valid. Accordingly, both the absolute values of the accessible plasma parameters and their trends for varying RF power agree well in measurement and simulation. At varying RF power, the H- current extracted from the Linac4 source peaks at 40 kW. For volume operation, this is perfectly reflected by assessing the processes in front of the extraction aperture based on the simulation results where the highest H- density is obtained for the same power level. In surface operation, the production of negative hydrogen ions at the converter surface can only be considered by specialized beam formation codes, which require plasma parameters as input. It has been demonstrated that this input can be provided reliably by the NINJA code.

Mechanism of blue-light-induced plasma-membrane depolarization in etiolated cucumber hypocotyls

NASA Technical Reports Server (NTRS)

Spalding, E. P.; Cosgrove, D. J.

1992-01-01

A large, transient depolarization of the plasma membrane precedes the rapid blue-light (BL)-induced growth suppression in etiolated seedlings of Cucumis sativus L. The mechanism of this voltage transient was investigated by applying inhibitors of ion channels and the plasma-membrane H(+)-ATPase, by manipulating extracellular ion concentrations, and by measuring cell input resistance and ATP levels. The depolarizing phase was not affected by Ca(2+)-channel blockers (verapamil, La3+) or by reducing extracellular free Ca2+ by treatment with ethylene glycol-bis(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid (EGTA). However, these treatments did reduce the rate of repolarization, indicating an inward movement of Ca2+ is involved. No effects of the K(+)-channel blocker tetraethylammonium (TEA+) were detected. Vanadate and KCN, used to inhibit the H(+)-ATPase, reduced or completely inhibited the BL-induced depolarization. Levels of ATP increased by 11-26% after 1-2 min of BL. Input resistance of trichrome cells, measured with double-barreled microelectrodes, remained constant during the onset of the depolarization but decreased as the membrane voltage became more positive than -90 mV. The results indicate that the depolarization mechanism initially involves inactivation of the H(+)-ATPase with subsequent transient activation of one or more types of ion channels.

Database-driven web interface automating gyrokinetic simulations for validation

NASA Astrophysics Data System (ADS)

Ernst, D. R.

2010-11-01

We are developing a web interface to connect plasma microturbulence simulation codes with experimental data. The website automates the preparation of gyrokinetic simulations utilizing plasma profile and magnetic equilibrium data from TRANSP analysis of experiments, read from MDSPLUS over the internet. This database-driven tool saves user sessions, allowing searches of previous simulations, which can be restored to repeat the same analysis for a new discharge. The website includes a multi-tab, multi-frame, publication quality java plotter Webgraph, developed as part of this project. Input files can be uploaded as templates and edited with context-sensitive help. The website creates inputs for GS2 and GYRO using a well-tested and verified back-end, in use for several years for the GS2 code [D. R. Ernst et al., Phys. Plasmas 11(5) 2637 (2004)]. A centralized web site has the advantage that users receive bug fixes instantaneously, while avoiding the duplicated effort of local compilations. Possible extensions to the database to manage run outputs, toward prototyping for the Fusion Simulation Project, are envisioned. Much of the web development utilized support from the DoE National Undergraduate Fellowship program [e.g., A. Suarez and D. R. Ernst, http://meetings.aps.org/link/BAPS.2005.DPP.GP1.57.

Plasma-Based Tunable High Frequency Power Limiter

NASA Astrophysics Data System (ADS)

Semnani, Abbas; Macheret, Sergey; Peroulis, Dimitrios

2016-09-01

Power limiters are often employed to protect sensitive receivers from being damaged or saturated by high-power incoming waves. Although wideband low-power limiters based on semiconductor technology are widely available, the options for high-power frequency-selective ones are very few. In this work, we study the application of a gas discharge tube (GDT) integrated in an evanescent-mode (EVA) cavity resonator as a plasma-based power limiter. Plasmas can inherently handle higher power in comparison with semiconductor diodes. Also, using a resonant structure provides the ability of having both lower threshold power and frequency-selective limiting, which are important if only a narrowband high-power signal is targeted. Higher input RF power results in stronger discharge in the GDT and consequently higher electron density which results in larger reflection. It is also possible to tune the threshold power by pre-ionizing the GDT with a DC bias voltage. As a proof of concept, a 2-GHz EVA resonator loaded by a 90-V GDT was fabricated and measured. With reasonable amount of insertion loss, the limiting threshold power was successfully tuned from 8.3 W to 590 mW when the external DC bias was varied from 0 to 80 V. The limiter performed well up to 100 W of maximum available input power.

Nanotexturing of polystyrene surface in fluorocarbon plasmas: from sticky to slippery superhydrophobicity.

PubMed

Mundo, Rosa Di; Palumbo, Fabio; d'Agostino, Riccardo

2008-05-06

In this work plasma etching processes have been studied to roughen and fluorinate polystyrene surface as an easy method to achieve a superhydrophobic slippery character. Radiofrequency discharges have been fed with CF(4)/O(2) mixtures and the effect of the O(2):CF(4) ratio, the input power, and the treatment duration have been investigated in terms of wettability, with focus on sliding performances. For this purpose, surface morphological variations, evaluated by means of scanning electron microscopy and atomic force microscopy, together with the chemical assessment by X-ray photoelectron spectroscopy, have been correlated with water contact angle hysteresis and volume resolved sliding angle measurements. Results indicate that by increasing the height and decreasing the density of the structures formed by etching, within a tailored range, a transition from sticky to slippery superhydrophobicity occurs. A short treatment time (5 min) is sufficient to obtain such an effect, provided that a high power input is utilized. Optimized surfaces show a unaltered transparency to visible light according to the low roughness produced.

NO removal by nonthermal plasma with modified sepiolite catalyst

NASA Astrophysics Data System (ADS)

Chen, M. G.; Yu, D. X.; Rong, J. F.; Wan, Y. L.; Li, G. C.; Ni, Y. M.; Fan, X.; Hou, G. H.; Xu, N.

2013-03-01

Non-Thermal Plasma (NTP) combined with a catalyst is one of the effective ways to remove NO from auto exhaust gas. Sepiolite Ore Powder (SOP), which was modified by acid washing, copper nitrate soaking, drying and calcinations, served as the Modified Sepiolite Catalyst (MSC) for NO removal in a rod-cylinder Dielectric Barrier Discharge (DBD) reactor. The characteristic of the MSC was characterized by X-ray powder diffraction (XRD) and scanning electron microscopy (SEM). The experiment showed that the acid concentration, washing time, the packed site of MSC and input voltage of the NTP impacted the NO removal rate effectively. The NO removal rate increased and then decreased with an increase in the acid concentration and the washing time, and the NO removal rate increased monotonously with the increased input voltage. The NO removal rate was higher at the beginning, decreased gradually then maintained stability after 10 min. Thus, the result indicated that MSC has a good ability for adsorption and storage of NO.

A one-model approach based on relaxed combinations of inputs for evaluating input congestion in DEA

NASA Astrophysics Data System (ADS)

Khodabakhshi, Mohammad

2009-08-01

This paper provides a one-model approach of input congestion based on input relaxation model developed in data envelopment analysis (e.g. [G.R. Jahanshahloo, M. Khodabakhshi, Suitable combination of inputs for improving outputs in DEA with determining input congestion -- Considering textile industry of China, Applied Mathematics and Computation (1) (2004) 263-273; G.R. Jahanshahloo, M. Khodabakhshi, Determining assurance interval for non-Archimedean ele improving outputs model in DEA, Applied Mathematics and Computation 151 (2) (2004) 501-506; M. Khodabakhshi, A super-efficiency model based on improved outputs in data envelopment analysis, Applied Mathematics and Computation 184 (2) (2007) 695-703; M. Khodabakhshi, M. Asgharian, An input relaxation measure of efficiency in stochastic data analysis, Applied Mathematical Modelling 33 (2009) 2010-2023]. This approach reduces solving three problems with the two-model approach introduced in the first of the above-mentioned reference to two problems which is certainly important from computational point of view. The model is applied to a set of data extracted from ISI database to estimate input congestion of 12 Canadian business schools.

Can Simulation Credibility Be Improved Using Sensitivity Analysis to Understand Input Data Effects on Model Outcome?

NASA Technical Reports Server (NTRS)

Myers, Jerry G.; Young, M.; Goodenow, Debra A.; Keenan, A.; Walton, M.; Boley, L.

2015-01-01

Model and simulation (MS) credibility is defined as, the quality to elicit belief or trust in MS results. NASA-STD-7009 [1] delineates eight components (Verification, Validation, Input Pedigree, Results Uncertainty, Results Robustness, Use History, MS Management, People Qualifications) that address quantifying model credibility, and provides guidance to the model developers, analysts, and end users for assessing the MS credibility. Of the eight characteristics, input pedigree, or the quality of the data used to develop model input parameters, governing functions, or initial conditions, can vary significantly. These data quality differences have varying consequences across the range of MS application. NASA-STD-7009 requires that the lowest input data quality be used to represent the entire set of input data when scoring the input pedigree credibility of the model. This requirement provides a conservative assessment of model inputs, and maximizes the communication of the potential level of risk of using model outputs. Unfortunately, in practice, this may result in overly pessimistic communication of the MS output, undermining the credibility of simulation predictions to decision makers. This presentation proposes an alternative assessment mechanism, utilizing results parameter robustness, also known as model input sensitivity, to improve the credibility scoring process for specific simulations.

Analysis of ISS Plasma Interaction

NASA Technical Reports Server (NTRS)

Reddell, Brandon; Alred, John; Kramer, Leonard; Mikatarian, Ron; Minow, Joe; Koontz, Steve

2006-01-01

To date, the International Space Station (ISS) has been one of the largest objects flown in lower earth orbit (LEO). The ISS utilizes high voltage solar arrays (160V) that are negatively grounded leading to pressurized elements that can float negatively with respect to the plasma. Because laboratory measurements indicate a dielectric breakdown potential difference of 80V, arcing could occur on the ISS structure. To overcome the possibility of arcing and clamp the potential of the structure, two Plasma Contactor Units (PCUs) were designed, built, and flown. Also a limited amount of measurements of the floating potential for the present ISS configuration were made by a Floating Potential Probe (FPP), indicating a minimum potential of 24 Volts at the measurement location. A predictive tool, the ISS Plasma Interaction Model (PIM) has been developed accounting for the solar array electron collection, solar array mast wire and effective conductive area on the structure. The model has been used for predictions of the present ISS configuration. The conductive area has been inferred based on available floating potential measurements. Analysis of FPP and PCU data indicated distribution of the conductive area along the Russian segment of the ISS structure. A significant input to PIM is the plasma environment. The International Reference Ionosphere (IRI 2001) was initially used to obtain plasma temperature and density values. However, IRI provides mean parameters, leading to difficulties in interpretation of on-orbit data, especially at eclipse exit where maximum charging can occur. This limits our predicative capability. Satellite and Incoherent Scatter Radar (ISR) data of plasma parameters have also been collected. Approximately 130,000 electron temperature (Te) and density (Ne) pairs for typical ISS eclipse exit conditions have been extracted from the reduced Langmuir probe data flown aboard the NASA DE-2 satellite. Additionally, another 18,000 Te and Ne pairs of ISR data from several radar locations around the globe were used to assure consistency of the satellite data. PIM predictions for ISS charging made with this data correlated very well with FPP data, indicating that the general physics of spacecraft charging with high voltage solar arrays have been captured. The predictions also provided the probabilities of occurrences for ISS charging. These probabilities give a numerical measure of the number of times when the ISS will approach or exceed the vehicle plasma hazard conditions for each configuration. In this paper we shall present the interaction mechanisms between the ISS and the surrounding plasma and give an overview of the PIM components. PIM predictions are compared with available data followed by a discussion of the variability of plasma parameters and the conductive area on the ISS. The ISS PIM will be further tested and verified as data from the Floating Potential Measurement Unit become available, and construction of the ISS continues.

Spatio-temporal analysis of the electron power absorption in electropositive capacitive RF plasmas based on moments of the Boltzmann equation

NASA Astrophysics Data System (ADS)

Schulze, J.; Donkó, Z.; Lafleur, T.; Wilczek, S.; Brinkmann, R. P.

2018-05-01

Power absorption by electrons from the space- and time-dependent electric field represents the basic sustaining mechanism of all radio-frequency driven plasmas. This complex phenomenon has attracted significant attention. However, most theories and models are, so far, only able to account for part of the relevant mechanisms. The aim of this work is to present an in-depth analysis of the power absorption by electrons, via the use of a moment analysis of the Boltzmann equation without any ad-hoc assumptions. This analysis, for which the input quantities are taken from kinetic, particle based simulations, allows the identification of all physical mechanisms involved and an accurate quantification of their contributions. The perfect agreement between the sum of these contributions and the simulation results verifies the completeness of the model. We study the relative importance of these mechanisms as a function of pressure, with high spatial and temporal resolution, in an electropositive argon discharge. In contrast to some widely accepted previous models we find that high space- and time-dependent ambipolar electric fields outside the sheaths play a key role for electron power absorption. This ambipolar field is time-dependent within the RF period and temporally asymmetric, i.e., the sheath expansion is not a ‘mirror image’ of the sheath collapse. We demonstrate that this time-dependence is mainly caused by a time modulation of the electron temperature resulting from the energy transfer to electrons by the ambipolar field itself during sheath expansion. We provide a theoretical proof that this ambipolar electron power absorption would vanish completely, if the electron temperature was constant in time. This mechanism of electron power absorption is based on a time modulated electron temperature, markedly different from the Hard Wall Model, of key importance for energy transfer to electrons on time average and, thus, essential for the generation of capacitively coupled plasmas.

Structurally Integrated Coatings for Wear and Corrosion (SICWC): Arc Lamp, InfraRed (IR) Thermal Processing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mackiewicz-Ludtka, G.; Sebright, J.

2007-12-15

The primary goal of this Cooperative Research and Development Agreement (CRADA) betwe1311 UT-Battelle (Contractor) and Caterpillar Inc. (Participant) was to develop the plasma arc lamp (PAL), infrared (IR) thermal processing technology 1.) to enhance surface coating performance by improving the interfacial bond strength between selected coatings and substrates; and 2.) to extend this technology base for transitioning of the arc lamp processing to the industrial Participant. Completion of the following three key technical tasks (described below) was necessary in order to accomplish this goal. First, thermophysical property data sets were successfully determined for composite coatings applied to 1010 steel substrates,more » with a more limited data set successfully measured for free-standing coatings. These data are necessary for the computer modeling simulations and parametric studies to; A.) simulate PAL IR processing, facilitating the development of the initial processing parameters; and B.) help develop a better understanding of the basic PAL IR fusing process fundamentals, including predicting the influence of melt pool stirring and heat tnmsfar characteristics introduced during plasma arc lamp infrared (IR) processing; Second, a methodology and a set of procedures were successfully developed and the plasma arc lamp (PAL) power profiles were successfully mapped as a function of PAL power level for the ORNL PAL. The latter data also are necessary input for the computer model to accurately simulate PAL processing during process modeling simulations, and to facilitate a better understand of the fusing process fundamentals. Third, several computer modeling codes have been evaluated as to their capabilities and accuracy in being able to capture and simulate convective mixing that may occur during PAL thermal processing. The results from these evaluation efforts are summarized in this report. The intention of this project was to extend the technology base and provide for transitioning of the arc lamp processing to the industrial Participant.« less

Low-pressure hydrogen plasmas explored using a global model

NASA Astrophysics Data System (ADS)

Samuell, Cameron M.; Corr, Cormac S.

2016-02-01

Low-pressure hydrogen plasmas have found applications in a variety of technology areas including fusion, neutral beam injection and material processing applications. To better understand these discharges, a global model is developed to predict the behaviour of electrons, ground-state atomic and molecular hydrogen, three positive ion species (H+, \\text{H}2+ , and \\text{H}3+ ), a single negative ion species (H-), and fourteen vibrationally excited states of molecular hydrogen ({{\\text{H}}2}≤ft(\\upsilon =1\\right. -14)). The model is validated by comparison with experimental results from a planar inductively coupled GEC reference cell and subsequently applied to the MAGPIE linear helicon reactor. The MAGPIE reactor is investigated for a range of pressures from 1 to 100 mTorr and powers up to 5 kW. With increasing power between 50 W and 5 kW at 10 mTorr the density of all charged species increases as well as the dissociative fraction while the electron temperature remains almost constant at around 3 eV. For gas pressures from 1-100 mTorr at an input power of 1 kW, the electron density remains almost constant, the electron temperature and dissociative fraction decreases, while \\text{H}3+ density increases in density and also dominates amongst ion species. Across these power and pressure scans, electronegativity remains approximately constant at around 2.5%. The power and pressure determines the dominant ion species in the plasma with \\text{H}3+ observed to dominate at high pressures and low powers whereas H+ tends to be dominant at low pressures and high powers. A sensitivity analysis is used to demonstrate how experimental parameters (power, pressure, reactor wall material, geometry etc) influence individual species’ density as well as the electron temperature. Physical reactor changes including the length, radius and wall recombination coefficient are found to have the largest influence on outputs obtained from the model.

Serotonin involvement in pituitary-adrenal function

NASA Technical Reports Server (NTRS)

Vernikos-Danellis, J.; Kellar, K. J.; Kent, D.; Gonzales, C.; Berger, P. A.; Barchas, J. D.

1977-01-01

Experiments clarifying the effects of serotonin (5-HT) in the regulation of the hypothalamic-pituitary-adrenocortical system are surveyed. Lesion experiments which seek to determine functional maps of serotonergic input to areas involved in regulation are reported. Investigations of the effects of 5-HT levels on the plasma ACTH response to stress and the diurnal variation in basal plasma corticosterone are summarized, and the question of whether serotonergic transmission is involved in the regulation of all aspects of pituitary-adrenal function is considered with attention to the stimulatory and inhibitory action of 5-HT.

Laser Heating of Magnetically Confined Plasmas for X-Ray Production.

DTIC Science & Technology

1976-04-01

self atsrm r~ t ion factor (SAF) is an arbitrary program input whose inverse PF2’ IFCT = SA F ’ mul t ip l ies Equation (3.25 ) to set a black body limit...from He-like neon to severa l MW. A detailed hydrodynamic and atomic physics program developed for this project— .~ ~~~ DD ~~~~~~~ 1473 I H I ’ I D...Sciences North- west , Inc . (MSNW) program for DNA , laser heating of magnetically con- fined plasma columns was demonstrated and moderate Z gases (neon

Measurements of energy distribution and thrust for microwave plasma coupling of electrical energy to hydrogen for propulsion

NASA Technical Reports Server (NTRS)

Morin, T.; Chapman, R.; Filpus, J.; Hawley, M.; Kerber, R.; Asmussen, J.; Nakanishi, S.

1982-01-01

A microwave plasma system for transfer of electrical energy to hydrogen flowing through the system has potential application for coupling energy to a flowing gas in the electrothermal propulsion concept. Experimental systems have been designed and built for determination of the energy inputs and outputs and thrust for the microwave coupling of energy to hydrogen. Results for experiments with pressure in the range 100 microns-6 torr, hydrogen flow rate up to 1000 micronmoles/s, and total absorbed power to 700 w are presented.

Boltzmann expansion in a radiofrequency conical helicon thruster operating in xenon and argon

DOE Office of Scientific and Technical Information (OSTI.GOV)

Charles, C.; Boswell, R.; Takahashi, K.

2013-06-03

A low pressure ({approx}0.5 mTorr in xenon and {approx}1 mTorr in argon) Boltzmann expansion is experimentally observed on axis within a magnetized (60 to 180 G) radiofrequency (13.56 MHz) conical helicon thruster for input powers up to 900 W using plasma parameters measured with a Langmuir probe. The axial forces, respectively, resulting from the electron and magnetic field pressures are directly measured using a thrust balance for constant maximum plasma pressure and show a higher fuel efficiency for argon compared to xenon.

Apparatus and method for removing particle species from fusion-plasma-confinement devices

DOEpatents

Hamilton, G.W.

1981-10-26

In a mirror fusion plasma confinement apparatus, method and apparatus are provided for selectively removing (pumping) trapped low energy (thermal) particle species from the end cell region, without removing the still useful high energy particle species, and without requiring large power input to accomplish the pumping. Perturbation magnets are placed in the thermal barrier region of the end cell region at the turning point characteristic of trapped thermal particles, thus deflecting the thermal particles from their closed trajectory, causing them to drift sufficiently to exit the thermal barrier.

Reliability of a new biokinetic model of zirconium in internal dosimetry: part I, parameter uncertainty analysis.

PubMed

Li, Wei Bo; Greiter, Matthias; Oeh, Uwe; Hoeschen, Christoph

2011-12-01

The reliability of biokinetic models is essential in internal dose assessments and radiation risk analysis for the public, occupational workers, and patients exposed to radionuclides. In this paper, a method for assessing the reliability of biokinetic models by means of uncertainty and sensitivity analysis was developed. The paper is divided into two parts. In the first part of the study published here, the uncertainty sources of the model parameters for zirconium (Zr), developed by the International Commission on Radiological Protection (ICRP), were identified and analyzed. Furthermore, the uncertainty of the biokinetic experimental measurement performed at the Helmholtz Zentrum München-German Research Center for Environmental Health (HMGU) for developing a new biokinetic model of Zr was analyzed according to the Guide to the Expression of Uncertainty in Measurement, published by the International Organization for Standardization. The confidence interval and distribution of model parameters of the ICRP and HMGU Zr biokinetic models were evaluated. As a result of computer biokinetic modelings, the mean, standard uncertainty, and confidence interval of model prediction calculated based on the model parameter uncertainty were presented and compared to the plasma clearance and urinary excretion measured after intravenous administration. It was shown that for the most important compartment, the plasma, the uncertainty evaluated for the HMGU model was much smaller than that for the ICRP model; that phenomenon was observed for other organs and tissues as well. The uncertainty of the integral of the radioactivity of Zr up to 50 y calculated by the HMGU model after ingestion by adult members of the public was shown to be smaller by a factor of two than that of the ICRP model. It was also shown that the distribution type of the model parameter strongly influences the model prediction, and the correlation of the model input parameters affects the model prediction to a certain extent depending on the strength of the correlation. In the case of model prediction, the qualitative comparison of the model predictions with the measured plasma and urinary data showed the HMGU model to be more reliable than the ICRP model; quantitatively, the uncertainty model prediction by the HMGU systemic biokinetic model is smaller than that of the ICRP model. The uncertainty information on the model parameters analyzed in this study was used in the second part of the paper regarding a sensitivity analysis of the Zr biokinetic models.

Microwave Driven Magnetic Plasma Accelerator Studies (CYCLOPS)

NASA Technical Reports Server (NTRS)

Crimi, G. F.; Eckert, A. C.; Miller, D. B.

1967-01-01

A microwave-driven cyclotron resonance plasma acceleration device was investigated using argon, krypton, xenon, and mercury as propellants. Limited ranges of propellant flow rate, input power, and magnetic field strength were used. Over-all efficiencies (including the 65% efficiency of the input polarizer) less than 10% were obtained for specific impulse values between 500 and 1500 sec. Power transfer efficiencies, however, approached 100% of the input power available in the right-hand component of the incident circularly polarized radiation. Beam diagnostics using Langmuir probes, cold gas mapping, r-f mapping and ion energy analyses were performed in conjunction with an engine operating in a pulsed mode. Measurements of transverse electron energies at the position of cyclotron resonant absorption yielded energy values more than an order of magnitude lower than anticipated. The measured electron energies were, however, consistent with the low values of average ion energy measured by retarding potential techniques. The low values of average ion energy were also consistent with the measured thrust values. It is hypothesized that ionization and radiation limit the electron kinetic energy to low-values thus limiting the energy which is finally transferred to the ion. Thermalization by electron-electron collision was also identified as an additional loss mechanism. The use of light alkali metals, which have relatively few low lying energy levels to excite, with the input power to mass ratio selected so as to limit the electron energies to less than the second ionization potential, is suggested. It is concluded, however, that the over-all efficiency for such propellants would be less than 40 per cent.

Health economic evaluation of plasma oxysterol screening in the diagnosis of Niemann-Pick Type C disease among intellectually disabled using discrete event simulation.

PubMed

van Karnebeek, Clara D M; Mohammadi, Tima; Tsao, Nicole; Sinclair, Graham; Sirrs, Sandra; Stockler, Sylvia; Marra, Carlo

2015-02-01

Recently a less invasive method of screening and diagnosing Niemann-Pick C (NP-C) disease has emerged. This approach involves the use of a metabolic screening test (oxysterol assay) instead of the current practice of clinical assessment of patients suspected of NP-C (review of medical history, family history and clinical examination for the signs and symptoms). Our objective is to compare costs and outcomes of plasma oxysterol screening versus current practice in diagnosis of NP-C disease among intellectually disabled (ID) patients using decision-analytic methods. A discrete event simulation model was conducted to follow ID patients through the diagnosis and treatment of NP-C, forecast the costs and effectiveness for a cohort of ID patients and compare the outcomes and costs in two different arms of the model: plasma oxysterol screening and routine diagnosis procedure (anno 2013) over 5 years of follow up. Data from published sources and clinical trials were used in simulation model. Unit costs and quality-adjusted life-years (QALYs) were discounted at a 3% annual rate in the base case analysis. Deterministic and probabilistic sensitivity analyses were conducted. The outcomes of the base case model showed that using plasma oxysterol screening for diagnosis of NP-C disease among ID patients is a dominant strategy. It would result in lower total cost and would slightly improve patients' quality of life. The average amount of cost saving was $3642 CAD and the incremental QALYs per each individual ID patient in oxysterol screening arm versus current practice of diagnosis NP-C was 0.0022 QALYs. Results of sensitivity analysis demonstrated robustness of the outcomes over the wide range of changes in model inputs. Whilst acknowledging the limitations of this study, we conclude that screening ID children and adolescents with oxysterol tests compared to current practice for the diagnosis of NP-C is a dominant strategy with clinical and economic benefits. The less costly, more sensitive and specific oxysterol test has potential to save costs to the healthcare system while improving patients' quality of life and may be considered as a routine tool in the NP-C diagnosis armamentarium for ID. Further research is needed to elucidate its effectiveness in patients presenting characteristics other than ID in childhood and adolescence. Copyright © 2014 Elsevier Inc. All rights reserved.

Effects of Meteorological Data Quality on Snowpack Modeling

NASA Astrophysics Data System (ADS)

Havens, S.; Marks, D. G.; Robertson, M.; Hedrick, A. R.; Johnson, M.

2017-12-01

Detailed quality control of meteorological inputs is the most time-intensive component of running the distributed, physically-based iSnobal snow model, and the effect of data quality of the inputs on the model is unknown. The iSnobal model has been run operationally since WY2013, and is currently run in several basins in Idaho and California. The largest amount of user input during modeling is for the quality control of precipitation, temperature, relative humidity, solar radiation, wind speed and wind direction inputs. Precipitation inputs require detailed user input and are crucial to correctly model the snowpack mass. This research applies a range of quality control methods to meteorological input, from raw input with minimal cleaning, to complete user-applied quality control. The meteorological input cleaning generally falls into two categories. The first is global minimum/maximum and missing value correction that could be corrected and/or interpolated with automated processing. The second category is quality control for inputs that are not globally erroneous, yet are still unreasonable and generally indicate malfunctioning measurement equipment, such as temperature or relative humidity that remains constant, or does not correlate with daily trends observed at nearby stations. This research will determine how sensitive model outputs are to different levels of quality control and guide future operational applications.

Numerical simulation of an oxygen-fed wire-to-cylinder negative corona discharge in the glow regime

NASA Astrophysics Data System (ADS)

Yanallah, K.; Pontiga, F.; Castellanos, A.

2011-02-01

Negative glow corona discharge in flowing oxygen has been numerically simulated for a wire-to-cylinder electrode geometry. The corona discharge is modelled using a fluid approximation. The radial and axial distributions of charged and neutral species are obtained by solving the corresponding continuity equations, which include the relevant plasma-chemical kinetics. Continuity equations are coupled with Poisson's equation and the energy conservation equation, since the reaction rate constants may depend on the electric field and temperature. The experimental values of the current-voltage characteristic are used as input data into the numerical calculations. The role played by different reactions and chemical species is analysed, and the effect of electrical and geometrical parameters on ozone generation is investigated. The reliability of the numerical model is verified by the reasonable agreement between the numerical predictions of ozone concentration and the experimental measurements.

JET DT Scenario Extrapolation and Optimization with METIS

NASA Astrophysics Data System (ADS)

Urban, Jakub; Jaulmes, Fabien; Artaud, Jean-Francois

2017-10-01

Prospective JET (Joint European Torus) DT operation scenarios are modelled by the fast integrated code METIS. METIS combines scaling laws, e.g. for global and pedestal energy or density peaking, with simplified transport and source models, while retaining fundamental nonlinear couplings, in particular in the fusion power. We have tuned METIS parameters to match JET-ILW high performance experiments, including baseline and hybrid. Based on recent observations, we assume a weaker input power scaling than IPB98 and a 10% confinement improvement due to the higher ion mass. The rapidity of METIS is utilized to scan the performance of JET DT scenarios with respect to fundamental parameters, such as plasma current, magnetic field, density or heating power. Simplified, easily parameterized waveforms are used to study the effect the ramp-up speed or heating timing. Finally, an efficient Bayesian optimizer is employed to seek the most performant scenarios in terms of the fusion power or gain.

First Breakthrough for Future Air-Breathing Magneto-Plasma Propulsion Systems

NASA Astrophysics Data System (ADS)

Göksel, B.; Mashek, I. Ch

2017-04-01

A new breakthrough in jet propulsion technology since the invention of the jet engine is achieved. The first critical tests for future air-breathing magneto-plasma propulsion systems have been successfully completed. In this regard, it is also the first time that a pinching dense plasma focus discharge could be ignited at one atmosphere and driven in pulse mode using very fast, nanosecond electrostatic excitations to induce self-organized plasma channels for ignition of the propulsive main discharge. Depending on the capacitor voltage (200-600 V) the energy input at one atmosphere varies from 52-320 J/pulse corresponding to impulse bits from 1.2-8.0 mNs. Such a new pulsed plasma propulsion system driven with one thousand pulses per second would already have thrust-to-area ratios (50-150 kN/m²) of modern jet engines. An array of thrusters could enable future aircrafts and airships to start from ground and reach altitudes up to 50km and beyond. The needed high power could be provided by future compact plasma fusion reactors already in development by aerospace companies. The magneto-plasma compressor itself was originally developed by Russian scientists as plasma fusion device and was later miniaturized for supersonic flow control applications. So the first breakthrough is based on a spin-off plasma fusion technology.

Constraining the astrophysical origin of the p-nuclei through nuclear physics and meteoritic data.

PubMed

Rauscher, T; Dauphas, N; Dillmann, I; Fröhlich, C; Fülöp, Zs; Gyürky, Gy

2013-06-01

A small number of naturally occurring, proton-rich nuclides (the p-nuclei) cannot be made in the s- and r-processes. Their origin is not well understood. Massive stars can produce p-nuclei through photodisintegration of pre-existing intermediate and heavy nuclei. This so-called γ-process requires high stellar plasma temperatures and occurs mainly in explosive O/Ne burning during a core-collapse supernova. Although the γ-process in massive stars has been successful in producing a large range of p-nuclei, significant deficiencies remain. An increasing number of processes and sites has been studied in recent years in search of viable alternatives replacing or supplementing the massive star models. A large number of unstable nuclei, however, with only theoretically predicted reaction rates are included in the reaction network and thus the nuclear input may also bear considerable uncertainties. The current status of astrophysical models, nuclear input and observational constraints is reviewed. After an overview of currently discussed models, the focus is on the possibility to better constrain those models through different means. Meteoritic data not only provide the actual isotopic abundances of the p-nuclei but can also put constraints on the possible contribution of proton-rich nucleosynthesis. The main part of the review focuses on the nuclear uncertainties involved in the determination of the astrophysical reaction rates required for the extended reaction networks used in nucleosynthesis studies. Experimental approaches are discussed together with their necessary connection to theory, which is especially pronounced for reactions with intermediate and heavy nuclei in explosive nuclear burning, even close to stability.

Quantum theory for the dynamic structure factor in correlated two-component systems in nonequilibrium: Application to x-ray scattering.

PubMed

Vorberger, J; Chapman, D A

2018-01-01

We present a quantum theory for the dynamic structure factors in nonequilibrium, correlated, two-component systems such as plasmas or warm dense matter. The polarization function, which is needed as the input for the calculation of the structure factors, is calculated in nonequilibrium based on a perturbation expansion in the interaction strength. To make our theory applicable for x-ray scattering, a generalized Chihara decomposition for the total electron structure factor in nonequilibrium is derived. Examples are given and the influence of correlations and exchange on the structure and the x-ray-scattering spectrum are discussed for a model nonequilibrium distribution, as often encountered during laser heating of materials, as well as for two-temperature systems.

Quantum theory for the dynamic structure factor in correlated two-component systems in nonequilibrium: Application to x-ray scattering

NASA Astrophysics Data System (ADS)

Vorberger, J.; Chapman, D. A.

2018-01-01

We present a quantum theory for the dynamic structure factors in nonequilibrium, correlated, two-component systems such as plasmas or warm dense matter. The polarization function, which is needed as the input for the calculation of the structure factors, is calculated in nonequilibrium based on a perturbation expansion in the interaction strength. To make our theory applicable for x-ray scattering, a generalized Chihara decomposition for the total electron structure factor in nonequilibrium is derived. Examples are given and the influence of correlations and exchange on the structure and the x-ray-scattering spectrum are discussed for a model nonequilibrium distribution, as often encountered during laser heating of materials, as well as for two-temperature systems.

Wide-view charge exchange recombination spectroscopy diagnostic for Alcator C-Mod.

PubMed

Rowan, W L; Bespamyatnov, I O; Granetz, R S

2008-10-01

This diagnostic measures temperature, density, and rotation for the fully stripped boron ion between the pedestal top and the plasma core with resolution consistent with the profile gradients. The diagnostic neutral beam used for the measurements generates a 50 keV, 6 A hydrogen beam. The optical systems provide views in both poloidal and toroidal directions. The imaging spectrometer is optimized to simultaneously accept 45 views as input with minimum cross-talk. In situ calibration techniques are applied for spatial location, spectral intensity, and wavelength. In the analysis, measured spectra are fitted to a model constructed from a detailed description of the emission physics. Methods for removal of interfering spectra are included. Applications include impurity and thermal transport.

Building an infrastructure at PICKSC for the educational use of kinetic software tools

NASA Astrophysics Data System (ADS)

Mori, W. B.; Decyk, V. K.; Tableman, A.; Fonseca, R. A.; Tsung, F. S.; Hu, Q.; Winjum, B. J.; Amorim, L. D.; An, W.; Dalichaouch, T. N.; Davidson, A.; Joglekar, A.; Li, F.; May, J.; Touati, M.; Xu, X. L.; Yu, P.

2016-10-01

One aim of the Particle-In-Cell and Kinetic Simulation Center (PICKSC) at UCLA is to coordinate a community development of educational software for undergraduate and graduate courses in plasma physics and computer science. The rich array of physical behaviors exhibited by plasmas can be difficult to grasp by students. If they are given the ability to quickly and easily explore plasma physics through kinetic simulations, and to make illustrative visualizations of plasma waves, particle motion in electromagnetic fields, instabilities, or other phenomena, then they can be equipped with first-hand experiences that inform and contextualize conventional texts and lectures. We are developing an infrastructure for any interested persons to take our kinetic codes, run them without any prerequisite knowledge, and explore desired scenarios. Furthermore, we are actively interested in any ideas or input from other plasma physicists. This poster aims to illustrate what we have developed and gather a community of interested users and developers. Supported by NSF under Grant ACI-1339893.

Enhancement of carbon-steel peel adhesion to rubber blend using atmospheric pressure plasma

NASA Astrophysics Data System (ADS)

Kršková, Jana; Skácelová, Dana; Kováčik, Dušan; Ráhel', Jozef; Pret'o, Jozef; Černák, Mirko

2016-08-01

The surface of carbon-steel plates was modified by non-equilibrium plasma of diffuse coplanar surface barrier discharge (DCSBD) in order to improve the adhesive properties to the NR (natural rubber) green rubber compound. The effect of different treatment times as well as different input power and frequency of supplied high voltage was investigated. The samples were characterized using contact angle and surface free energy measurement, measurement of adhesive properties, scanning electron microscopy (SEM) and atomic force microscopy (AFM). Surface chemical composition was studied by energy-dispersive X-ray spectroscopy (EDX). Significant increase in wettability was observed even after 2 s of plasma exposure. The surface modification was confirmed also by peel test, where the best results were obtained for 6 s of plasma treatment. In addition the ageing effect was studied to investigate the durability of modification, which is crucial for the industrial applications. Contribution to the topical issue "6th Central European Symposium on Plasma Chemistry (CESPC-6)", edited by Nicolas Gherardi, Ester Marotta and Cristina Paradisi

Understanding Coronal Heating through Time-Series Analysis and Nanoflare Modeling

NASA Astrophysics Data System (ADS)

Romich, Kristine; Viall, Nicholeen

2018-01-01

Periodic intensity fluctuations in coronal loops, a signature of temperature evolution, have been observed using the Atmospheric Imaging Assembly (AIA) aboard NASA’s Solar Dynamics Observatory (SDO) spacecraft. We examine the proposal that nanoflares, or impulsive bursts of energy release in the solar atmosphere, are responsible for the intensity fluctuations as well as the megakelvin-scale temperatures observed in the corona. Drawing on the work of Cargill (2014) and Bradshaw & Viall (2016), we develop a computer model of the energy released by a sequence of nanoflare events in a single magnetic flux tube. We then use EBTEL (Enthalpy-Based Thermal Evolution of Loops), a hydrodynamic model of plasma response to energy input, to simulate intensity as a function of time across the coronal AIA channels. We test the EBTEL output for periodicities using a spectral code based on Mann and Lees’ (1996) multitaper method and present preliminary results here. Our ultimate goal is to establish whether quasi-continuous or impulsive energy bursts better approximate the original SDO data.

One-dimensional bubble model of pulsed discharge in water

NASA Astrophysics Data System (ADS)

Lu, XinPei

2007-09-01

In this paper, a one-dimensional bubble model of pulsed discharge in water is presented. With a total input energy of 0.63J, the simulation results show that when the bubble collapses at the center of the bubble, the plasma pressure oscillates strongly. It oscillates between 800 and 1150atm with an oscillation frequency of about 6.9MHz, while at r =R/2 (R: bubble radius), the gas velocity oscillates intensely at the same frequency. It oscillates between -235 and 229m/s when the bubble radius reaches its minimum. But it does not oscillate at r =R because of the inertia of the surrounding water. The bubble collapses and reexpands with almost the same speed as that of the zero-dimensional (0D) model. This further confirms why the shock wave pressure from the 0D mode has a good agreement with the experimental results since the shock wave pressure is only determined by the bubble wall velocity v(R ).

Experiments on Alfv'en waves in high beta plasmas

NASA Astrophysics Data System (ADS)

Gekelman, Walter; Pribyl, Patrick; Cooper, Chris; Vincena, Stephen

2008-11-01

The propagation of Alfv'en waves in high beta plasmas is of great interest in solar wind studies as well as in astrophysical plasmas. Alfv'en wave propagation in a high beta plasma is studied on the axis of a toroidal device at UCLA. The vacuum vessel is 30 meters in circumference, 2 meters wide and 3 meters tall. The plasma has a cross sectional area of 20 cm^2 and can be as long as 120 m which is hundreds of parallel Alfv'en wavelengths. The waves are launched using two orthogonal 5-turn , 5.7 cm diameter loops. The AC currents (10 kHz < f < 250 kHz) to the loops are as high as 2 kA p-p, producing fields of 1 kG on the axis of the antenna. The antenna coils are independently driven such that waves with arbitrary polarization can be launched. Movable three axis magnetic pickup loops detect the wave and are used to construct field maps in the machine. Wave propagation results as a function of plasma beta and input wave energy will be presented.

Spectrometer employing optical fiber time delays for frequency resolution

DOEpatents

Schuss, Jack J.; Johnson, Larry C.

1979-01-01

This invention provides different length glass fibers for providing a broad range of optical time delays for short incident chromatic light pulses for the selective spatial and frequency analysis of the light with a single light detector. To this end, the frequencies of the incident light are orientated and matched with the different length fibers by dispersing the separate frequencies in space according to the respective fiber locations and lengths at the input terminal of the glass fibers. This makes the different length fibers useful in the field of plasma physics. To this end the short light pulses can be scattered by a plasma and then passed through the fibers for analyzing and diagnosing the plasma while it varies rapidly with time.

Noise characteristics of a plasma relativistic microwave amplifier

DOE Office of Scientific and Technical Information (OSTI.GOV)

Strelkov, P. S., E-mail: strelkov@fpl.gpi.ru; Ivanov, I. E.; Shumeiko, D. V.

2016-07-15

Reasons for the occurrence of microwave noise at the output of a plasma relativistic amplifier have been analyzed. It is found that, in the absence of an input signal, the emission spectrum of the plasma relativistic microwave amplifier is similar to that of an electron beam in vacuum. It is concluded that microwave noise at the output of the amplifier appears as a result of amplification of the intrinsic noise of the electron beam. The emission characteristics of a relativistic electron beam formed in a magnetically insulated diode with an explosive emission cathode in vacuum have been studied experimentally formore » the first time. An important point is that, in this case, there is no virtual cathode in the drift space.« less

Effect of heat input on microstructure, wear and friction behavior of (wt.-%) 50FeCrC-20FeW-30FeB coating on AISI 1020 produced by using PTA welding.

PubMed

Özel, Cihan; Gürgenç, Turan

2018-01-01

In this study, AISI 1020 steel surface was coated in different heat inputs with (wt.-%) 50FeCrC-20FeW-30FeB powder mixture by using plasma transferred arc (PTA) welding method. The microstructure of the coated samples were investigated by using optical microscope (OM), scanning electron microscope (SEM), X-ray diffraction (XRD) and energy dispersive X-ray (EDS). The hardness was measured with micro hardness test device. The dry sliding wear and friction coefficient properties were determined using a block-on-disk type wear test device. Wear tests were performed at 19.62 N, 39.24 N, 58.86 N load and the sliding distance of 900 m. The results were shown that different microstructures formed due to the heat input change. The highest average micro hardness value was measured at 1217 HV on sample coated with low heat input. It was determined that the wear resistance decreased with increasing heat input.

Effect of heat input on microstructure, wear and friction behavior of (wt.-%) 50FeCrC-20FeW-30FeB coating on AISI 1020 produced by using PTA welding

PubMed Central

Gürgenç, Turan

2018-01-01

In this study, AISI 1020 steel surface was coated in different heat inputs with (wt.-%) 50FeCrC-20FeW-30FeB powder mixture by using plasma transferred arc (PTA) welding method. The microstructure of the coated samples were investigated by using optical microscope (OM), scanning electron microscope (SEM), X-ray diffraction (XRD) and energy dispersive X-ray (EDS). The hardness was measured with micro hardness test device. The dry sliding wear and friction coefficient properties were determined using a block-on-disk type wear test device. Wear tests were performed at 19.62 N, 39.24 N, 58.86 N load and the sliding distance of 900 m. The results were shown that different microstructures formed due to the heat input change. The highest average micro hardness value was measured at 1217 HV on sample coated with low heat input. It was determined that the wear resistance decreased with increasing heat input. PMID:29324875