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Sample records for plasma switches

  1. Triggered plasma opening switch

    DOEpatents

    Mendel, Clifford W.

    1988-01-01

    A triggerable opening switch for a very high voltage and current pulse includes a transmission line extending from a source to a load and having an intermediate switch section including a plasma for conducting electrons between transmission line conductors and a magnetic field for breaking the plasma conduction path and magnetically insulating the electrons when it is desired to open the switch.

  2. Plasma opening switch

    DOEpatents

    Savage, Mark E.; Mendel, Jr., Clifford W.

    2001-01-01

    A command triggered plasma opening switch assembly using an amplification stage. The assembly surrounds a coaxial transmission line and has a main plasma opening switch (POS) close to the load and a trigger POS upstream from the main POS. The trigger POS establishes two different current pathways through the assembly depended on whether it has received a trigger current pulse. The initial pathway has both POS's with plasma between their anodes and cathodes to form a short across the transmission line and isolating the load. The final current pathway is formed when the trigger POS receives a trigger current pulse which energizes its fast coil to push the conductive plasma out from between its anode and cathode, allowing the main transmission line current to pass to the fast coil of the main POS, thus pushing its plasma out the way so as to establish a direct current pathway to the load.

  3. Plasma Switch Development.

    DTIC Science & Technology

    1984-06-08

    switch :9 (1) the low-pressure gas switch 17 (2) the surface flashover switch ,18 (3) the thyrtron,’ŕ (4) the high pressure...spark gap, (5) the magnetic switch .’ 9 20 and (6) the ECS. The ongoing research for both the low pressure gas and surface flashover closing- switches has... investigations into optimizing gas mixtures for opening switch applications 1 ’"’"’’’a𔃻 ; and a preliminary study of the discharge stabili-

  4. Megavolt, Multigigawatt Pulsed Plasma Switch

    NASA Technical Reports Server (NTRS)

    Lee, Ja H.; Choi, Sang H.; Song, Kyo D.

    1996-01-01

    Plasma switch proposed for use in high-voltage, high-current pulse power system. Designed not only to out-perform conventional spark-gap switch but also relatively compact and lightweight. Features inverse-pinch configuration to prevent constriction of current sheets into filaments, plus multiple-ring-electrode structure to resist high-voltage breakdown.

  5. Characteristics of switching plasma in an inverse-pinch switch

    NASA Technical Reports Server (NTRS)

    Lee, Ja H.; Choi, Sang H.; Venable, Demetrius D.; Han, Kwang S.; Nam, Sang H.

    1993-01-01

    Characteristics of the plasma that switches on tens of giga volt-ampere in an inverse-pinch plasma switch (INPIStron) have been made. Through optical and spectroscopic diagnostics of the current carrying plasma, the current density, the motion of current paths, dominant ionic species have been determined in order to access their effects on circuit parameters and material erosion. Also the optimum operational condition of the plasma-puff triggering method required for azimuthally uniform conduction in the INPIStron has been determined.

  6. Magnetic field penetration of erosion switch plasmas

    NASA Astrophysics Data System (ADS)

    Mason, Rodney J.; Jones, Michael E.; Grossmann, John M.; Ottinger, Paul F.

    1988-10-01

    Computer simulations demonstrate that the entrainment (or advection) of magnetic field with the flow of cathode-emitted electrons can constitute a dominant mechanism for the magnetic field penetration of erosion switch plasmas. Cross-field drift in the accelerating electric field near the cathode starts the penetration process. Plasma erosion propagates the point for emission and magnetic field injection along the cathode toward the load-for the possibility of rapid switch opening.

  7. High Voltage Switch Using Externally Ionized Plasmas.

    DTIC Science & Technology

    1980-04-01

    circuit breakers were not considered because their re- sponse is too slow to meet the on/off and PRF requirements. These constraints narrowed the number of...ELECTRON-BEAM PLASMA SWITCH STUDY 4 2.1 Model Description 4 2.1.1 Plasma and Circuit Models 4 2.1.2 Electron Beam Source Model 8 2.2 Gas Selection...70 "usttloatIon ~in Diutribut 0. is Avail and/or sit pecial 4/ LIST OF ILLUSTRATIONS FIGURE PAGE 1. Circuit Assumed in the Switch Computer Program 6

  8. Launched electrons in plasma opening switches

    NASA Astrophysics Data System (ADS)

    Mendel, C. W., Jr.; Rochau, G. E.; Sweeney, M. A.; McDaniel, D. H.; Quintenz, J. P.; Savage, M. E.; Lindman, E. L.; Kindel, J. M.

    Plasma opening switches have provided a means to improve the characteristics of super-power pulse generators. Recent advances involving plasma control with fast and slow magnetic fields have made these switches more versatile, allowing for improved switch uniformity, triggering, and opening current levels that are set by the level of auxiliary fields. Such switches necessarily involve breaks in the translational symmetry of the transmission line geometry and therefore affect the electron flow characteristics of the line. These symmetry breaks are the result of high electric field regions caused by plasma conductors remaining in the transmission line, ion beams crossing the line, or auxilliary magnetic field regions. Symmetry breaks cause the canonical momentum of the electrons to change, thereby moving them away from the cathode. Additional electrons are pulled from the cathode into the magnetically insulated flow, resulting in an excess of electron flow over that expected for the voltage and line current downstream of the switch. These electrons are called launched electrons. Unless they are recaptured at the cathode or else are fed into the load and used beneficially, they cause a large power loss downstream. Examples are shown of SuperMite and PBFA II data showing these losses, the tools used to study them are explained, and the mechanisms employed to mitigate the problem are discussed. The losses will be reduced primarily by reducing the amount of launched electron flow.

  9. Plasma dynamics in microsecond megaampere plasma opening switches

    SciTech Connect

    Loginov, S. V.

    2011-10-15

    The paper considers the transport of a magnetic field in highly ionized plasma of microsecond megaampere plasma opening switches. Self-similar solutions for plasma aggregation by a linearly increasing magnetic field are derived. For these solutions, the magnetic field energy in the current channel is much lower than the energy of the accelerated plasma flow. The effect of Joule heating of the plasma becomes profound only with a uniform current density. It is shown that the evolution of the magnetic field in the accelerated flow is reduced to diffusion with an effective electrical conductivity proportional to the harmonic average of the Spitzer conductivity and conductivity dependent on the magnetic field in the current channel. Thus, during about the first 100 ns of the current pulse the conductivity of the current channel increases due to the plasma heating and, as the plasma is accelerated, its conductivity decreases.

  10. The Liquid Metal Plasma Valve Closing Switch

    DTIC Science & Technology

    1976-11-01

    Specifications Closing HVDC LMPV Switch Converter LMPV Circuit Parameter Parameters Rating Breaker Rating Peak Voltage 50-200 kV 150 kV nominal 30...last column of the table outliner the ratings of the LMPV used in an existing circuit breaker system. The capability of the LMPV to operate at high...1976. W. 0. Eckhardt and G. A. Hofmann, ’’Ohmic Heading DC Circuit Breakers with Liquid-Metal Plasma Valves, 11 Proceedings of the Ninth Symposium on

  11. Plasma flow switch experiments on the Pegasus facility

    SciTech Connect

    Cochrane, J.C. Jr.; Anderson, B.; Bartsch, R.R.; Bowers, R.; Findley, C.; Greene, A.; Kruse, H.; Oona, H.; Parker, J.V.; Peterson, D.; Sandoval, G. ); Lee, P.H.Y. ); Turchi, P. )

    1991-01-01

    Plasma flow switch experiments conducted on Pegasus have shown that a conducting layer of plasma shunts the load slot preventing efficient switching of current to the load. This effect is seen computationally. The magnitude of the effect depends on the specific parameters of the switch plasma and current level. Computations have also shown that a plasma boundary layer trap'' would effectively remove enough plasma from the inner conductor of the power flow channel so that efficient switching would occur. This plasma trap has been successfully demonstrated when used with a static load. It has not yet been tested with an imploding load. 3 refs., 8 figs.

  12. Review of switching arcs and plasma chemistry

    NASA Astrophysics Data System (ADS)

    Benenson, D. M.; Gilmour, A. S., Jr.; Dollinger, R. E.; Nagamatsu, H. T.; Pfender, E.; Warder, R. C., Jr.

    1980-05-01

    Physical processes in switching arcs are considered in such applications as circuit interruption (in high pressure, high voltage gas blast circuit breakers and vacuum arc interrupters), fault current limiting (principally through vacuum arc devices), and pulse power systems (using vacuum arcs). The physics of arc heaters, associated with processes in the anode region, are described. Analytical models of (1) the current zero region and interrupter performance of gas blast interrupters and (2) the heat transfer mechanisms in the anode region of arc heaters, are discussed. Selected diagnostic techniques are presented. Applications of plasma chemistry involving the high pressure, equilibrium (thermal) plasma are noted. Low pressure (nonequilibrium) plasma processing is described through mechanisms associated with coating, deposition, and etching applications.

  13. Multi-gap high impedance plasma opening switch

    DOEpatents

    Mason, Rodney J.

    1996-01-01

    A high impedance plasma opening switch having an anode and a cathode and at least one additional electrode placed between the anode and cathode. The presence of the additional electrodes leads to the creation of additional plasma gaps which are in series, increasing the net impedance of the switch. An equivalent effect can be obtained by using two or more conventional plasma switches with their plasma gaps wired in series. Higher impedance switches can provide high current and voltage to higher impedance loads such as plasma radiation sources.

  14. Multi-gap high impedance plasma opening switch

    DOEpatents

    Mason, R.J.

    1996-10-22

    A high impedance plasma opening switch having an anode and a cathode and at least one additional electrode placed between the anode and cathode is disclosed. The presence of the additional electrodes leads to the creation of additional plasma gaps which are in series, increasing the net impedance of the switch. An equivalent effect can be obtained by using two or more conventional plasma switches with their plasma gaps wired in series. Higher impedance switches can provide high current and voltage to higher impedance loads such as plasma radiation sources. 12 figs.

  15. Current-level triggered plasma-opening switch

    DOEpatents

    Mendel, C.W.

    1987-06-29

    An opening switch for very high power electrical pulses uses a slow magnetic field to confine a plasma across a gap between two electrodes. The plasma conducts the electric pulse across the gap while the switch is closed. A magnetic field generated by the pulse repels the slow magnetic field from the negative electrode to push the plasma from the electrode, opening the switch. A plurality of radial vanes may be used to enhance the slow magnetic field. 5 figs.

  16. Current-level triggered plasma-opening switch

    DOEpatents

    Mendel, Clifford W.

    1989-01-01

    An opening switch for very high power electrical pulses uses a slow magnetic field to confine a plasma across a gap between two electrodes. The plasma conducts the electric pulse across the gap while the switch is closed. A magnetic field generated by the pulse repels the slow magnetic field from the negative electrode to push the plasma from the electrode, opening the switch. A plurality of radial vanes may be used to enhance the slow magnetic field.

  17. Design and characterization of the Pegasus I plasma flow switch

    SciTech Connect

    Wysocki, F.J.; Bartsch, R.R.; Bowers, R.L.; Cochrane, J.C.; Greene, A.E.; Ladish, J.S.; Lee, P.H.Y.; Parker, J.V.; Peterson, D.L.; Benage, J.F.; Gribble, R.F.; Shlachter, J.S.; Scudder, D.W. ); Roderick, N.F. ); Turchi, P.J. )

    1992-01-01

    A plasma flow switch (PFS) based on an experimental design utilized at the Air Force Weapons Laboratory (AFWL) has been fielded on the Pegasus I system. Currents of as much as 5.8 MA have been switched on a time scale (10--90%) of 200 ns into a static load. Tests with a foil load have resulted in a less than ideal current transfer because of interaction between the dynamic load and the plasma flow switch. Two-dimensional radiation magnetohydrodynamic (RMHD) calculations have been used to characterize the behavior of the PFS and to aid in the design. These calculations have also been used to investigate several classes of perturbations in the switch-plasma, the interaction of the switch-plasma with the coaxial electrodes, and their effect on switching efficiency. The Pegasus I PFS experiments reproduce the results obtained at AFWL throughout the switch initiation and switching phases. However, early in the foil implosion the switched current drops significantly. We believe this current drop results from a small amount of residual plasma left behind in the PFS region that impedes the magnetic-flux transport, thereby preventing efficient foil implosion. The experimental results suggest that the method of PFS initiation (viz. chordal wire arrays) may be an important factor in switch operation.

  18. A long life plasma switch for space applications

    NASA Technical Reports Server (NTRS)

    Choi, Sang H.; Lee, Ja H.

    1987-01-01

    The use of a novel plasma switch based on the inverse-pinch mechanism can reduce local current density over spacecraft power system electrodes, thereby minimizing damage to the insulator. The current density involved is 2 orders of magnitude smaller than that of the z-pinched current in a spark-gap switch; local heating is therefore about 4 orders of magnitude less than that to the electrodes of the spark-gap switch. Over 2000 tests of the plasma switch have been conducted for a forward current of more than 1 MA and up to 20 kV holdoff voltage.

  19. A novel carbon gun for use with plasma opening switches

    NASA Astrophysics Data System (ADS)

    Stevenson, P.; Gregory, K.; Cliffe, R. J.; Smith, I. R.

    2001-06-01

    The carbon gun is probably the most common plasma source used in plasma opening switches. Nevertheless, it either produces a contaminated plasma, as the flashover surface erodes, or requires regular treatment with graphite paint. The novel form of the plasma gun described in this paper overcomes the disadvantages of existing designs and produces a cleaner plasma. Experimental results illustrate the performance of a prototype system.

  20. Experiments on a current-toggled plasma-opening switch

    SciTech Connect

    Mendel, C.W. Jr.; Savage, M.E.; Zagar, D.M.; Simpson, W.W.; Grasser, T.W.; Quintenz, J.P. )

    1992-04-15

    Plasma-opening switches have been used to improve pulsed-power wave shapes for over a decade. These switches have used the inertia of the plasma to hold the switch closed. This results in conflicting requirements when long hold-off time and fast opening are required, and also results in variation in opening current due to variation in initial plasma fill. The current-toggled plasma-opening switch attempts to overcome these problems by using external magnetic fields rather than inertia to control the plasma conductor. Data will be presented showing several features of the operation of this switch. These data will be compared to models used to design the switch. The comparisons indicate that the mass can be measured approximately from fast coil data and that the slow coil flux does set the opening level of the current. They also indicate that the opening current is somewhat dependent upon plasma mass, and that the design of the field coils that provide the control fields must be done more carefully to provide a switch that opens satisfactorily.

  1. Plasma-puff initiation of high Coulomb transfer switches

    NASA Technical Reports Server (NTRS)

    Han, Kwang S.; Venable, Demetrius D.; Lee, Ja H.; Choi, Eun H.; Kim, Y. K.; Kim, J. H.; Nguyen, D. X.

    1993-01-01

    The plasma-puff triggering mechanism based on a hypocycloidal pinch geometry was investigated to determine the optimal operating conditions for an azimuthally uniform surface flashover which initiates plasma-puff under wide ranges of fill gas pressures of Ar, He and N2. The optimal fill gas pressures for the azimuthally uniform plasma-puff were about 120 mTorr less than P(sub opt) less than 450 Torr for He and N2. For Argon 20 mTorr is less than P(sub opt) is less than 5 Torr. The inverse pinch switch was triggered with the plasma-puff and the switching capability under various electrical parameters and working gas pressures of Ar, He and N2 was determined. It was also shown that the azimuthally uniform switching discharges were dependent on the type of fill gas and its fill pressure. A new concept of plasma-focus driven plasma-puff was also discussed in comparison with hypocycloidal pinch plasma-puff triggering. The main discharge of the inverse pinch switch with the plasma-focus driven plasma-puff trigger is found to be more azimuthally uniform than that with the hypocycloidal pinch plasma-puff trigger in a gas pressure region between 80 mTorr and 1 Torr. In order to assess the effects of plasma current density on material erosion of electrodes, emissions from both an inverse-pinch plasma switch (INPIStron) and from a spark gap switch under test were studied with an optical multichannel analyzer (OMA). The color temperature of the argon plasma was approximately 4,000 K which corresponded with the peak continuum emission near 750 nm. There are the strong line emissions of argon in the 650 - 800 nm range and a lack of line emissions of copper and other solid material used in the switch. This indicates that the plasma current density during closing is low and the hot spot or hot filament in the switch is negligible. This result also indicates considerable reduction of line emission with the INPIStron switch over that of a spark-gap switch. However, a strong carbon

  2. Plasma-puff initiation of high Coulomb transfer switches

    NASA Technical Reports Server (NTRS)

    Venable, D. D.; Han, K. S.

    1993-01-01

    The plasma-puff triggering mechanism based on a hypocycloidal pinch geometry was investigated to determine the optimal operating conditions for an azimuthally uniform surface flashover which initiates plasma-puff under wide ranges of fill gas pressures of Ar, He and N2. The optimal fill gas pressures for the azimuthally uniform plasma-puff were about 120 mTorr less than P(opt) less than 450 Torr for He and N2. For Argon 120 mTorr less than P(opt) less than 5 Torr for argon. The inverse pinch switch was triggered with the plasma-puff and the switching capability under various electrical parameters and working gas pressures of Ar, He and N2 was determined. It was also shown that the azimuthally uniform switching discharges were dependent on the type of fill gas and its fill pressure. A new concept of plasma-focus driven plasma-puff was also discussed in comparison with hypocycloidal pinch plasma-puff triggering. The main discharge of the inverse pinch switch with the plasma-focus driven plasma-puff trigger is found to be more azimuthally uniform than that with the hypocycloidal pinch plasma-puff trigger in a gas pressure region between 80 mTorr and 1 Torr. In order to assess the effects of plasma current density on material erosion of electrodes, emissions from both an inverse-pinch plasma switch (INPIStron) and from a spark gap switch under test were studied with an optical multichannel analyzer (OMA). The color temperature of the argon plasma was approximately 4,000 K which corresponded with the peak continuum emission near 750 nm. There are the strong line emissions of argon in the 650 - 800 nm range and a lack of line emissions of copper and other solid material used in the switch. This indicates that the plasma current density during closing is low and the hot spot or hot filament in the switch is negligible. This result also indicates considerable reduction of line emission with the INPIStron switch over that of a spark-gap switch. However, a strong carbon line

  3. Plasma opening switch studies of an applied Bz ion diode

    NASA Astrophysics Data System (ADS)

    Struckman, C. K.; Kusse, B. R.; Meyerhofer, D. D.; Rondeau, G.

    1989-05-01

    The light ion accelerator (1.5 MV, 4 ohms) at Cornell University is being used to study the characteristics of an applied Bz, or 'barrel', diode. The results of a series of experiments utilizing a plasma opening switch are reported. With a magnetically insulated ion diode load, the peak diode voltage increase from 1.5 to 1.8 MV and the ion power increased from 50 to 80 GW when a plasma opening switch was used.

  4. Studies of the Plasma Triggering Mechanism of Inverse Pinch Switch

    DTIC Science & Technology

    1993-11-10

    Studies of the Plasma Puff Triggering Mechanism 02 of Inverse Pinch Switch AD-A276 117 Final Report ElEC 0 A Principal Investigator Kwang S. Han Nov...based on a hypocycloidal pinch geometry was investigated to determine the optimal operating conditions for the azimuthally uniform surface flashover ...in the switch . In this study, the plasma-puff triggering mechanism based on a hypocycloidal pinch geometry was investigated to determine the optimal

  5. Plasma puff initiation of high Coulomb transfer switches

    NASA Technical Reports Server (NTRS)

    Venable, D. D.; Choi, E. H.

    1990-01-01

    The plasma-puff triggering mechanism based on a hypocycloidal pinch geometry was investigated to determine the optimal operating conditions for the azimuthally uniform surface flashover which initiates plasma-puff under wide range of fill gas pressure of Ar, He and N2. The optimal fill gas pressure for the azimuthally uniform plasma-puff was about 120 mTorr and 450 Torr for He and N2, and between 120 mTorr and 5 Torr for Ar. The inverse pinch switch was triggered with the plasma-puff and the switching capability under various electrical parameters and working gas pressures of Ar, He and N2 was determined. It was also shown that the azimuthally uniform switching discharges were dependent on the type of fill gas and its fill pressure. A new concept of plasma-focus driven plasma-puff was also discussed in comparison with the hypocycloidal pinch plasma-puff triggering. The main discharge of inverse pinch switch with plasma-focus driven plasma-puff trigger is found to be more azimuthally uniform than that with hypocycloidal pinch plasma-puff trigger in a gas pressure region between 80 mTorr and 1 Torr.

  6. The Liquid Metal Plasma Valve Closing Switch,

    DTIC Science & Technology

    1976-01-01

    Table 1. Switch Specification s Closing HVDC LMPV Switch Converter LMPV Circuit Parameter...Parameters Rating Breaker Rating Peak Voltage 50-200 kV 150 kV nominal 30 kV Pulse Width 20-50 1isec 6 msec 20 msec Peak Current 8-4 kA 1.8 kA nominal

  7. Anthem simulational studies of the plasma opening switch

    SciTech Connect

    Mason, R.J.

    1992-01-01

    For a deeper understanding of the physical processes governing the Plasma Opening Switch (POS) we use the ANTHEM 2D implicit simulation code to study: (1) ion dynamical effects on electrohydrodynamic (EHD) waves propagating along steep density interfaces in the switch plasmas. At radial interfaces where the density jumps toward the anode, these waves can drive a finger of magnetic field into the plasma toward the load. Ion dynamics can open the rear of such fingers into a wedge-like density gap. Then: (2) we examine ion effects in uniform switch plasmas. These first develop potential hill structures at the drive edge of the cathode from the competition between electron velocity advection and EHD magnetic exclusion waves. Magnetic pressure gradients at the hill periphery and EHD effects then establish a density gap propagating along the cathode with radial electron emission from its tip. Similar results are obtained under both multi-fluid and PIC modeling of the plasma components.

  8. Anthem simulational studies of the plasma opening switch

    SciTech Connect

    Mason, R.J.

    1992-07-01

    For a deeper understanding of the physical processes governing the Plasma Opening Switch (POS) we use the ANTHEM 2D implicit simulation code to study: (1) ion dynamical effects on electrohydrodynamic (EHD) waves propagating along steep density interfaces in the switch plasmas. At radial interfaces where the density jumps toward the anode, these waves can drive a finger of magnetic field into the plasma toward the load. Ion dynamics can open the rear of such fingers into a wedge-like density gap. Then: (2) we examine ion effects in uniform switch plasmas. These first develop potential hill structures at the drive edge of the cathode from the competition between electron velocity advection and EHD magnetic exclusion waves. Magnetic pressure gradients at the hill periphery and EHD effects then establish a density gap propagating along the cathode with radial electron emission from its tip. Similar results are obtained under both multi-fluid and PIC modeling of the plasma components.

  9. Plasma erosion switches with imploding plasma loads on a multiterawatt pulsed power generator

    NASA Astrophysics Data System (ADS)

    Stringfield, R.; Schneider, R.; Genuario, R. D.; Roth, I.; Childers, K.; Stallings, C.; Dakin, D.

    1981-03-01

    Plasma erosion switches have been fielded on the PITHON generator during imploding plasma experiments. Theta pinch plasma guns were used to inject carbon plasmas of densities in the range of 10 to the 12th to 10 to the 14th/cu cm between the electrodes of the vacuum power feed region, upstream from an imploding plasma load. Current monitors indicated that the erosion switches carried substantial current early in time, diverting it from the load. Late in the pulse the erosion switches opened, transferring the current to an imploding plasma with the effect of sharpening the current rise time at the load. Associated with the sharper rise time was an improvement in the quality of the plasma implosions. The results of varying the density and total number of particles in the plasma of the switches are presented with regard to the effect on the current along the vacuum feed and on the behavior of vacuum flowing electrons.

  10. Plasma erosion switches with imploding plasma loads on the pithon generator

    NASA Astrophysics Data System (ADS)

    Stringfield, R.; Schneider, R.; Genuario, R. D.; Roth, I.; Childers, K.; Stallings, C.; Dakin, D.

    1981-03-01

    Plasma erosion switches have been fielded on the PITHON generator during imploding plasma experiments. Theta pinch plasma guns were used to inject carbon plasmas of densities in the range 10 12-10 14/cm 3 between the electrodes of the vacuum power feed region, upstream from an imploding plasma load. Current monitors indicated that the erosion switches carried substantial current early in time, diverting it from the load. Late in the pulse the erosion switches opened, transferring the current to an imploding plasma with the effect of sharpening the current risetime at the load. Associated with the sharper risetime was an improvement in the quality of the plasma implosions. The results of varying the density and total number of particles in the plasma of the switches are presented with regard to the effect on the current along the vacuum feed and on the behavior of vacuum flowing electrons.

  11. Low voltage drop plasma switch for inverter and modulator applications

    NASA Astrophysics Data System (ADS)

    Goebel, D. M.; Poeschel, R. L.; Schumacher, R. W.

    1993-08-01

    A low forward voltage drop plasma switch has been developed for high-efficiency inverter and modulator applications. The switch, called the HOLLOTRON, is based on a grid-controlled, thermionic hollow-cathode discharge. A low forward voltage drop (10-20 V) is achieved by operating the hollow-cathode discharge in a static gas pressure of xenon. The dense plasma generated in the Ba-oxide dispenser hollow cathode is spread over a relatively large control grid area by a diverging magnetic field superimposed on the discharge. Interruption of the discharge current at high current densities (≳4 A/cm2) over the grid area is achieved by biasing the control grid sufficiently negative with respect to the plasma. The HOLLOTRON switch has demonstrated voltage stand-off of up to 20 kV, switching times of ≤0.3 μs, and pulse repetition frequencies of 20 kHz at 50% duty.

  12. Computer modeling of plasma flow switches-high current switching on Procyon

    SciTech Connect

    Bowers, R.L.; Greene, A.E.; Peterson, D.L.; Roderick, N.F.

    1993-09-01

    Procyon is a high explosive driven pulsed power system designed to drive plasma z-pinch experiments to the 1-MJ level. Details of this system are provided elsewhere in these proceedings. The final switching stage of the Procyon system is a plasma flow switch (PFS). Our most recent experiment (April 29, 1993) included a full power test of the PFS designed for the Procyon system. In this test the Mark IX explosively driven generator delivered 22 MA of current to the storage inductor. The slight flux compression that occurs in the explosively formed fuse (EFF) opening switch increased this current to 24.5 MA. The EFF then opened and switched 16.5 MA to the PFS. The PFS switched 15.5 MA to the load region (the slot that will contain an imploding foil liner in future experiments) with a 10-90 rise time of 500 ns. In this present paper we discuss the computer modeling we have done on this Procyon plasma flow switch. In the next section we discuss the design of the Procyon switch and preshot calculations. Although the April 1993 experiment was quite successful there were significant surprizes in the performance of the PFS. In the last sections of this paper we discuss the work we have done in understanding the results of this experiment and the conclusions that we have reached to date.

  13. Experiments on planar plasma flow switches at Los Alamos

    SciTech Connect

    Benage, J.F. Jr.; Wysocki, F.J.; Bowers, R.; Oona, H.

    1997-12-01

    The authors have performed a series of experiments on the Colt facility at Los Alamos to study the performance of plasma flow switches and to understand the important physics issues which affect that performance. These experiments were done in planar geometry on a small machine to allow for better diagnostic access and a higher repetition rate. The Colt facility is a capacitor bank which stores 300 kJ at maximum charge and produced a peak current of 1.1 MA in 2.0 microseconds for these experiments. The diagnostics used for these experiments included an array of b-dot probes, visible framing pictures, visible spectroscopy, and laser interferometry. Characteristics of the switch are determined from spatial and temporal profiles of the magnetic field and the spatial profile and temperature of the switch plasma. Here the authors present results from experiments for a variety of switch conditions.

  14. Plasma flow switch and foil implosion experiments on Pegasus II

    SciTech Connect

    Cochrane, J.C.; Bartsch, R.R.; Benage, J.R.; Forman, P.R.; Gribble, R.F.; Ladish, J.S.; Oona, H.; Parker, J.V.; Scudder, D.W.; Shlachter, J.S.; Wysocki, F.J.

    1993-07-01

    Pegasus II is the upgraded version of Pegasus, a pulsed power machine used in the Los Alamos AGEX (Above Ground EXperiments) program. A goal of the program is to produce an intense (> 100 TW) source of soft x-rays from the thermalization of the kinetic energy of a 1 to 10 MJ plasma implosion. The radiation pulse should have a maximum duration of several 10`s of nanoseconds and will be used in the study of fusion conditions and material properties. The radiating plasma source will be generated by the thermalization of the kinetic energy of an imploding cylindrical, thin, metallic foil. This paper addresses experiments done on a capacitor bank to develop a switch (plasma flow switch) to switch the bank current into the load at peak current. This allows efficient coupling of bank energy into foil kinetic energy.

  15. Plasma flow switch and foil implosion experiments on Pegasus II

    SciTech Connect

    Cochrane, J.C.; Bartsch, R.R.; Benage, J.R.; Forman, P.R.; Gribble, R.F.; Ladish, J.S.; Oona, H.; Parker, J.V.; Scudder, D.W.; Shlachter, J.S.; Wysocki, F.J.

    1993-01-01

    Pegasus II is the upgraded version of Pegasus, a pulsed power machine used in the Los Alamos AGEX (Above Ground EXperiments) program. A goal of the program is to produce an intense (> 100 TW) source of soft x-rays from the thermalization of the kinetic energy of a 1 to 10 MJ plasma implosion. The radiation pulse should have a maximum duration of several 10's of nanoseconds and will be used in the study of fusion conditions and material properties. The radiating plasma source will be generated by the thermalization of the kinetic energy of an imploding cylindrical, thin, metallic foil. This paper addresses experiments done on a capacitor bank to develop a switch (plasma flow switch) to switch the bank current into the load at peak current. This allows efficient coupling of bank energy into foil kinetic energy.

  16. Reversible plasma switching in epitaxial BiFeO{sub 3} thin films

    SciTech Connect

    Kim, Yunseok; Vrejoiu, Ionela; Hesse, Dietrich; Alexe, Marin

    2010-05-17

    Reversible plasma switching in epitaxial multiferroic BiFeO{sub 3} thin films was directly observed and analyzed using piezoresponse force microscopy. The polarization could be reversibly switched using oxygen plasma and a subsequent thermal annealing treatment in vacuum, respectively. The domain wall velocity during plasma switching, estimated to about 10{sup -8} m/s, is much slower compared to the normal electrical switching, however a large area of square centimeter scale could be stably switched. The results demonstrate that reversible plasma switching can be achieved by oxygen plasma treatment and it can be a useful tool for an electrode-less control of ferroelectric switching on large area.

  17. Spectroscopic investigation of species separation in opening switch plasmas

    NASA Astrophysics Data System (ADS)

    Jackson, S. L.; Phipps, D. G.; Richardson, A. S.; Commisso, R. J.; Hinshelwood, D. D.; Murphy, D. P.; Schumer, J. W.; Weber, B. V.; Boyer, C. N.; Doron, R.; Biswas, S.; Maron, Y.

    2015-11-01

    Interactions between magnetic fields and current-carrying plasmas that lead to the separation of plasma species in multi-species plasmas are being studied in a plasma opening switch geometry. Several Marshall guns are used to inject single or multi-species plasmas between coaxial conductors connected to the output of the Naval Research Laboratory's Hawk pulsed-power generator. Following injection of the plasma, the generator is used at roughly half power to apply an electrical pulse with a peak current of 450 kA, a peak voltage of 400 kV, and a rise time of 1.2 μs. The resulting magnetic field interacts with the plasma through a combination of field penetration and magnetohydrodynamic (MHD) pushing that is not well understood but can lead to the separation of plasma species in multi-species plasmas. An ICCD-coupled spectrometer has been used in combination with magnetic probes, a ribbon-beam interferometer, and particle-in-cell (PIC) modeling to diagnose and understand conditions in the plasma from the time it is injected until the end of the conduction phase of the opening switch. This work supported by the Naval Research Laboratory Base Program and the Office of Naval Research.

  18. Nonlinear magnetic field transport in opening switch plasmas

    SciTech Connect

    Mason, R.J. ); Auer, P.L.; Sudan, R.N.; Oliver, B.V.; Seyler, C.E.; Greenly, J.B. )

    1993-04-01

    The nonlinear transport of magnetic field in collisionless plasmas, as present in the plasma opening switch (POS), using the implicit multifluid simulation code ANTHEM [J. Comput. Phys. [bold 71], 429 (1987)] is studied. The focus is on early time behavior in the electron--magnetohydrodynamic (EMHD) limit, with the ions fixed, and the electrons streaming as a fluid under the influence of [bold v][sub [ital e

  19. Research on plasma-puff initiation of high Coulomb transfer switches

    NASA Technical Reports Server (NTRS)

    Venable, Demetrius D.; Han, Kwang S.

    1993-01-01

    The plasma-puff triggering mechanism based on hypocycloidal pinch geometry was investigated to determine the optimal operating conditions for an azimuthally uniform surface flashover which initiates plasma-puff under wide ranges of fill gas pressures of Ar, He and N2. Research is presented and resulting conference papers are attached. These papers include 'Characteristics of Plasma-Puff Trigger for an Inverse-Pinch Plasma Switch'; 'Ultra-High-Power Plasma Switch INPUTS for Pulse Power Systems'; 'Characteristics of Switching Plasma in an Inverse-Pinch Switch'; 'Comparative Study of INPIStron and Spark Gap'; and 'INPIStron Switched Pulsed Power for Dense Plasma Pinches.'

  20. Characterization of the conduction phase of a plasma opening switch using a hydrogen plasma

    NASA Astrophysics Data System (ADS)

    Moschella, J. J.; Klepper, C. C.; Vidoli, C.; Yadlowsky, E. J.; Weber, B. V.; Commisso, R. J.; Black, D. C.; Moosman, B.; Stephanakis, S. J.; Hinshelwood, D. D.; Maron, Y.

    2005-02-01

    Plasma opening switch (POS) experiments were conducted on the Hawk generator using an inverse pinch plasma source to inject a hydrogen plasma. Using a combination of interferometry, current measurements, and spectroscopic observations, it is shown that the conduction phase is characterized by the propagation of a current channel through the switch region that pushes a significant fraction of the plasma mass downstream, past the load edge of the switch. The data indicate that the current channel arrives at the load edge of the switch ≈550ns into the 950-ns-long conduction phase, in agreement with calculations based on J ×B displacement. Previously published POS experiments, using multispecies plasmas, observed that a relatively small fraction of the injected plasma mass propagated downstream and that the conduction phase ended soon after the current channel reached the load edge of the switch. It is suggested that the observed differences between these two types of switches involves the separation of ionic species subject to a magnetic force, where the light-ion plasma is pushed ahead of the magnetic field front and the heavier-ion plasma is penetrated by the field. Species-separation effects may be important in a multispecies POS but would be negligible in this almost pure (>95%) proton-plasma experiment. While the important role of the plasma composition in pulsed magnetic field plasma interactions has been pointed out in previous experimental studies, this work demonstrates that the plasma composition can have a significant effect on the conduction time of a POS.

  1. Nonlinear magnetic field transport in opening switch plasmas

    NASA Astrophysics Data System (ADS)

    Mason, R. J.; Auer, P. L.; Sudan, R. N.; Oliver, B. V.; Seyler, C. E.; Greenly, J. B.

    1993-04-01

    The nonlinear transport of magnetic field in collisionless plasmas, as present in the plasma opening switch (POS), using the implicit multifluid simulation code anthem [J. Comput. Phys. 71, 429 (1987)] is studied. The focus is on early time behavior in the electron-magnetohydrodynamic (EMHD) limit, with the ions fixed, and the electrons streaming as a fluid under the influence of ve×B Hall forces. Through simulation, magnetic penetration and magnetic exclusion waves are characterized, due to the Hall effect in the presence of transverse density gradients, and the interaction of these Hall waves with nonlinear diffusive disturbances from electron velocity advection, (veṡ∇)ve, is studied. It is shown how these mechanisms give rise to the anode magnetic insulation layer, central diffusion, and cathode potential hill structures seen in earlier opening switch plasmas studies.

  2. Design for Megavolt Inverse-Pinch Plasma Switch

    DTIC Science & Technology

    1989-06-01

    is fed into the HCP trigger electrode, electric flashover occurs over the ceramic disk insulator , and the resulting plasma sheet moves radially...the ratio of the insulator surface distance to the gas gap equal to 15.8 mm/5 mm or 3.2. The breakdown voltage over the insulator is thus 1.6 (=3.2... surface of the 1-MV switch is equal to that of the ones tested. Therefore, the switch will exceed the requirement. The charge transfer capability of the

  3. High-current plasmas switching devices

    NASA Astrophysics Data System (ADS)

    Mustafaev, Aleksandr; Grabovskiy, Artiom; Murillo, Oscar; Soukhomlinov, Vladimir

    2016-10-01

    Nowadays, the level of development of spatial and earthly nuclear energetic lays down big requirements: total control possibility of current density with a stable work of the instrument in extreme conditions with a big radiation level and temperatures of 1000 K. Among the ways of solving this problem the application of key elements with binary cesium-barium plasmas are available. The results of the investigation on electro-kinetic parameters of plasma Knudsen Cs-Ba key element with big current densities are presented in this work: >The phenomenon of spontaneous current breakage, which has a big influence on the efficiency of the grid extinction, was investigated; >Unique regimes of effective grid extinction, in which the rise of modulated power is realized with a declining of the energetic cost of controlling the current of the key element, were found; >Record energetic parameters for the binary key element were obtained: at an anode potential of 50 V, stable frequencies modulation at 1-10 kHz, the electric power density of 5 kW/cm2 and the efficiency more than 95%.

  4. Characterization of a microsecond-conduction-time plasma opening switch

    NASA Astrophysics Data System (ADS)

    Commisso, R. J.; Goodrich, P. J.; Grossmann, J. M.; Hinshelwood, D. D.; Ottinger, P. F.; Weber, B. V.

    1992-07-01

    This paper presents data and analyses from which emerges a physical picture of microsecond-conduction-time plasma opening switch operation. During conduction, a broad current channel penetrates axially through the plasma, moving it toward the load. Opening occurs when the current channel reaches the load end of the plasma, far from the load. During conduction, the axial line density in the interelectrode region is reduced from its value with no current conduction as a result of radial hydrodynamic forces associated with the current channel. A factor of 20 reduction is observed at opening in a small, localized region between the electrodes. When open, the switch plasma behaves like a section of magnetically insulated transmission line with an effective gap of 2 to 3 mm. Increasing the magnetic field in this gap by 50% results in an improvement of 50% in the peak load voltage and load current rise time, to 1.2 MV and 20 nsec, respectively. An erosion opening mechanism explains the inferred gap growth rate using the reduced line density at opening. Improved switch performance results when the maximum gap size is increased by using a rising load impedance.

  5. Plasma Switch for High-Power Active Pulse Compressor

    SciTech Connect

    Hirshfield, Jay L.

    2013-11-04

    Results are presented from experiments carried out at the Naval Research Laboratory X-band magnicon facility on a two-channel X-band active RF pulse compressor that employed plasma switches. Experimental evidence is shown to validate the basic goals of the project, which include: simultaneous firing of plasma switches in both channels of the RF circuit, operation of quasi-optical 3-dB hybrid directional coupler coherent superposition of RF compressed pulses from both channels, and operation of the X-band magnicon directly in the RF pulse compressor. For incident 1.2 ?s pulses in the range 0.63 ? 1.35 MW, compressed pulses of peak powers 5.7 ? 11.3 MW were obtained, corresponding to peak power gain ratios of 8.3 ? 9.3. Insufficient bakeout and conditioning of the high-power RF circuit prevented experiments from being conducted at higher RF input power levels.

  6. Investigation of opening switch mechanisms based on chemically reactive plasmas

    NASA Astrophysics Data System (ADS)

    Lapatovich, W. P.; Piejak, R. B.; Proud, J. M.

    1985-11-01

    An investigation of discharge-induced chemical reactions resulting in high-density product vapors containing strongly attaching gases has been conducted to evaluate the feasibility and potential of such reactions in rapid opening plasma switches. This new concept of employing such reactions to limit and/or interrupt large currents on a microsecond time scale was studied in two element (electrodeless and electroded) devices and in three element (electroded) devices. Bimolecular and unimolecular reactions were considered. The plasma reaction between AlCl sub 3 and SiO sub 2 was studied. The electrical properties of one of the reaction products (SiCl sub 4) is reported.

  7. INPIStron switched pulsed power for dense plasma pinches

    NASA Technical Reports Server (NTRS)

    Han, Kwang S.; Lee, Ja H.

    1993-01-01

    The inverse plasma switch INPIStron was employed for 10kJ/40kV capacitor bank discharge system to produce focused dense plasmas in hypocycloidal-pinch (HCP) devices. A single unit and an array of multiple HCP's were coupled as the load of the pulsed power circuit. The geometry and switching plasma dynamics were found advantageous and convenient for commutating the large current pulse from the low impedance transmission line to the low impedance plasma load. The pulse power system with a single unit HCP, the system A, was used for production of high temperature plasma focus and its diagnostics. The radially running down plasma dynamics, revealed in image converter photographs, could be simulated by a simple snow-plow model with a correction for plasma resistivity. The system B with an array of 8-HCP units which forms a long coaxial discharge chamber was used for pumping a Ti-sapphire laser. The intense UV emission from the plasma was frequency shifted with dye-solution jacket to match the absorption band of the Ti crystal laser near 500 nm. An untuned laser pulse energy of 0.6 J/pulse was obtained for 6.4 kJ/40 kV discharge, or near 103 times of the explosion limit of conventional flash lamps. For both systems the advantages of the INPIStron were well demonstrated: a single unit is sufficient for a large current (greater than 50 kA) without increasing the system impedance, highly reliable and long life operation and implied scalability for the high power ranges above I(sub peak) = 1 MA and V(sub hold) = 100 kV.

  8. INPIStron switched pulsed power for dense plasma pinches

    NASA Technical Reports Server (NTRS)

    Han, Kwang S.; Lee, Ja H.

    1993-01-01

    The inverse plasma switch INPIStron was employed for 10kJ/40kV capacitor bank discharge system to produce focused dense plasmas in hypocycloidal-pinch (HCP) devices. A single unit and an array of multiple HCP's were coupled as the load of the pulsed power circuit. The geometry and switching plasma dynamics were found advantageous and convenient for commutating the large current pulse from the low impedance transmission line to the low impedance plasma load. The pulse power system with a single unit HCP, the system A, was used for production of high temperature plasma focus and its diagnostics. The radially running down plasma dynamics, revealed in image converter photographs, could be simulated by a simple snow-plow model with a correction for plasma resistivity. The system B with an array of 8-HCP units which forms a long coaxial discharge chamber was used for pumping a Ti-sapphire laser. The intense UV emission from the plasma was frequency shifted with dye-solution jacket to match the absorption band of the Ti crystal laser near 500 nm. An untuned laser pulse energy of 0.6 J/pulse was obtained for 6.4 kJ/40 kV discharge, or near 103 times of the explosion limit of conventional flash lamps. For both systems the advantages of the INPIStron were well demonstrated: a single unit is sufficient for a large current (greater than 50 kA) without increasing the system impedance, highly reliable and long life operation and implied scalability for the high power ranges above I(sub peak) = 1 MA and V(sub hold) = 100 kV.

  9. INPIStron switched pulsed power for dense plasma pinches

    NASA Astrophysics Data System (ADS)

    Han, Kwang S.; Lee, Ja H.

    The inverse plasma switch INPIStron was employed for 10kJ/40kV capacitor bank discharge system to produce focused dense plasmas in hypocycloidal-pinch (HCP) devices. A single unit and an array of multiple HCP's were coupled as the load of the pulsed power circuit. The geometry and switching plasma dynamics were found advantageous and convenient for commutating the large current pulse from the low impedance transmission line to the low impedance plasma load. The pulse power system with a single unit HCP, the system A, was used for production of high temperature plasma focus and its diagnostics. The radially running down plasma dynamics, revealed in image converter photographs, could be simulated by a simple snow-plow model with a correction for plasma resistivity. The system B with an array of 8-HCP units which forms a long coaxial discharge chamber was used for pumping a Ti-sapphire laser. The intense UV emission from the plasma was frequency shifted with dye-solution jacket to match the absorption band of the Ti crystal laser near 500 nm. An untuned laser pulse energy of 0.6 J/pulse was obtained for 6.4 kJ/40 kV discharge, or near 103 times of the explosion limit of conventional flash lamps. For both systems the advantages of the INPIStron were well demonstrated: a single unit is sufficient for a large current (greater than 50 kA) without increasing the system impedance, highly reliable and long life operation and implied scalability for the high power ranges above I(sub peak) = 1 MA and V(sub hold) = 100 kV.

  10. Characteristics of plasma-puff trigger for a inverse-pinch plasma switch

    NASA Technical Reports Server (NTRS)

    Choi, Eun H.; Venable, Demetrius D.; Han, Kwang S.; Lee, Ja H.

    1993-01-01

    The plasma-puff triggering mechanism based on a hypocycloidal pinch geometry was investigated to determine the optimal operating conditions for the azimuthally uniform surface flashover which initiates plasma-puff under wide ranges of fill gas pressure of Ar, He and N2. The optimal fill-gas pressure range for the azimuthally uniform plasma-puff was about 120 mTorr less than or equal to P(sub op) less than or equal to 450 Torr for He and N2. For Argon 120 mTorr is less than or equal to P(sub op) is less than or equal to 5 Torr. The inverse-pinch switch was triggered with the plasma-puff and the switching capability under various electrical parameters and working gas pressures of Ar, He and N2 was determined. The azimuthally uniform switching discharges were dependent on the type of fill gas and its fill pressure. A new concept of plasma-focus driven plasma-puff will be discussed in comparison with the current hypocycloidal-pinch plasma-puff triggering.

  11. Characteristics of plasma-puff trigger for a inverse-pinch plasma switch

    NASA Technical Reports Server (NTRS)

    Choi, Eun H.; Venable, Demetrius D.; Han, Kwang S.; Lee, Ja H.

    1993-01-01

    The plasma-puff triggering mechanism based on a hypocycloidal pinch geometry was investigated to determine the optimal operating conditions for the azimuthally uniform surface flashover which initiates plasma-puff under wide ranges of fill gas pressure of Ar, He and N2. The optimal fill-gas pressure range for the azimuthally uniform plasma-puff was about 120 mTorr less than or equal to P(sub op) less than or equal to 450 Torr for He and N2. For Argon 120 mTorr is less than or equal to P(sub op) is less than or equal to 5 Torr. The inverse-pinch switch was triggered with the plasma-puff and the switching capability under various electrical parameters and working gas pressures of Ar, He and N2 was determined. The azimuthally uniform switching discharges were dependent on the type of fill gas and its fill pressure. A new concept of plasma-focus driven plasma-puff will be discussed in comparison with the current hypocycloidal-pinch plasma-puff triggering.

  12. MACH2 modeling of LANL plasma-flow-switch experiments

    SciTech Connect

    Wysocki, F.J.

    1994-12-31

    The plasma-flow opening-switch (PFS) is being developed at the Los Alamos National Laboratory as part of the Athena Program. The present goal is to switch 10--20 MA of current into a cylindrical-foil implosion load in 300--400 ns. Primary drivers currently in use include the Pegasus-II capacitor bank which delivers 8--10 MA to the PFS in 3--4 {mu}s and the Procyon explosively-driven flux-compression generator which delivers 15--18 MA in 2--3 {mu}s. A series of experiments using Pegasus-II and Procyon have characterized the PFS performance for a variety of experimental conditions. Issues examined with Pegasus-II include switch-mass (50-mg vs. 100-mg), switch fabrication (wire-array vs. graded-thickness-foil), current level (7 MA vs. 10 MA), presence or absence of a plasma trap, and static load vs. implosion load. Procyon has been used to characterize a PFS with a 1/r aerial-mass-density profile (as opposed to the Pegasus-II 1/r{sup 2} profile). The MACH2 two-dimensional magnetohydrodynamic code has been used to model these experiments and comparison of simulation data to the experimental data has been made. This includes direct comparison of data from an array of B-dot probes present on all tests (19--23 probes), direct comparison of x-ray yield and power for those tests with implosion loads, and qualitative comparison to framing and streak data. The agreement between simulation data and experimental data is reasonably good.

  13. Intense ion beam generation, plasma radiation source and plasma opening switch research

    NASA Astrophysics Data System (ADS)

    Hammer, D. A.; Coleman, M. D.; Qi, N.; Similon, P. L.; Sudan, R. N.

    1989-04-01

    This report describes research on intense ion beam diodes, plasma opening switches and dense z-pinch plasma radiators. Laser induced fluorescence spectroscopy has been used to map the electrostatic potential profile in a plasma-prefilled magnetically insulated ion diode. In a simple planar diode, the measured profile is inconsistent with the electrons being confined in a sheath near the cathode by the magnetic field. Rather, the profile implies the presence of electrons throughout the accelerating gap. A theoretical model of the penetration of current and magnetic field into a plasma, and of the current-driven effective collision frequency has been developed. The snowplow action of the rising magnetic field causes a steep rise in the plasma density at the leading edge. The subsequent multistreaming of the ions caused by ion reflection at the current layer could lead to ion heating through collective effects. The two-dimensional electron flow in the plasma cathode vacuum gap is also treated. Dense z-pinch plasma radiation source experiments have been initiated on the LION accelerator using gas puff and fine wire loads. The x-pinch was found to be a more effective way to generate soft x-rays than a single wire pinch or a gas puff implosion. Plasma opening switch experiments being initiated, and plasma anode ion diode development work being terminated are also briefly described.

  14. Variations in vacuum gap location in a microsecond plasma opening switch

    SciTech Connect

    Lisitsyn, I.V.; Kohno, S.; Kawauchi, T.; Akiyama, H.

    1997-10-01

    The process of vacuum gap formation in a microsecond plasma opening switch has been studied using a He{endash}Ne laser interferometer. Time and spatially resolved density measurements are performed in the plasma opening switch, showing a density decrease during switch opening in almost the whole interelectrode gap. Despite fine triggering accuracy and generally good shot-to-shot reproducibility of voltage and current waveforms, measurements made with the same laser beam location indicated remarkable shot-to-shot variation. The unstable formation of the vacuum gap in the microsecond plasma opening switch may be a major limiting factor for efficient switch operation. {copyright} {ital 1997 American Institute of Physics.}

  15. Plasma-filled applied B ion diode experiments using a plasma opening switch

    NASA Astrophysics Data System (ADS)

    Renk, T. J.

    1994-12-01

    In order for a plasma opening switch (POS) to open quickly and transfer power efficiently from an inductively charged vacuum transmission line to an applied B ion diode, the load impedance of the ion diode may be required to have an initial low impedance phase. A plasma-filled diode has such an impedance history. To test the effect of a plasma-filled diode on POS-diode coupling, a drifting plasma was introduced from the cathode side of an applied B ion diode operated on the LION accelerator (1.5 MV, 4 Ohm, 40 ns) at Cornell University. This plasma readily crossed the 2.1 T magnetic insulation field of the diode, and resulted in both increased diode electrical power, and an increased ability of the ion beam to remove material from a target. The plasma did not appear to have a noticeable effect on local beam steering angle.

  16. Plasma-filled applied B ion diode experiments using a plasma opening switch

    SciTech Connect

    Renk, T.J. )

    1994-12-15

    In order for a plasma opening switch (POS) to open quickly and transfer power efficiently from an inductively charged vacuum transmission line to an applied B ion diode, the load impedance of the ion diode may be required to have an initial low impedance phase. A plasma-filled diode has such an impedance history. To test the effect of a plasma-filled diode on POS-diode coupling, a drifting plasma was introduced from the cathode side of an applied B ion diode operated on the LION accelerator (1.5 MV, 4 [Omega], 40 ns) at Cornell University. This plasma readily crossed the 2.1 T magnetic insulation field of the diode, and resulted in both increased diode electrical power, and an increased ability of the ion beam to remove material from a target. The plasma did not appear to have a noticeable effect on local beam steering angle.

  17. Repetitive, plasma switched, gigawatt, ultra-wideband impulse transmitter development

    SciTech Connect

    Clark, R.S.; Rinehart, L.F.; Buttram, M.T.; Aurand, J.F.; Lundstrom, J.M.; Patterson, P.E.; Roose, L.D.; Crowe, W.

    1992-01-01

    Sandia National Laboratories has developed several repetitive, ultra-wideband (UWB), impulse transmitters to address impulse source, and to support experimental applications. The sources fall into two different classes, pulse peaking and pulse shorting. SNIPER (Sub-Nanosecond ImPulsE Radiator) is a source which uses an oil peaking switch to obtain a fast risetime (250-pS) pulse of 2-nS duration. The output voltage ranges between few tens of kilovolts to 250-kV. EMBL (EnantioMorphic Blumlein) is a similar device (presently under development) which uses a gas switch to short the falling portion of a 2-nS pulse to approximately 100-pS. To date, an output voltage of approximately 600-kV has been obtained (700-kV is the design goal). Depending upon the source, repetitive operation from single shot to 5-kHz (1-kHz nominal) has been obtained with excellent reliability and repeatability. Both sources are plasma switched impulse transmitters using a Hydrogen-thyratron based modulator, an oil-filled Blumlein (of two types), a peaking (or shorting) switch and a wideband TEM horn. Powers exceeding one-gigawatt are routinely generated. This technology appears to be extendable to at least 10-gigawatts. The frequency spectrum of the radiated pulse from these sources include the spectrum of 100-MHz to 3-GHz. The pulse is generated externally and then injected into the antenna. Due to the high powers involved and the need to radiate a broad spectrum of frequencies, Sandia has concentrated on TEM horn antennas. Several TEM horns have been built and used during this program. In those cases where higher gains are desired for the higher frequencies, TEM horn-fed dish antennas have been employed. A detailed overview of the UWB Transmitters along with measured radiated electric field strengths will be presented.

  18. Repetitive, plasma switched, gigawatt, ultra-wideband impulse transmitter development

    SciTech Connect

    Clark, R.S.; Rinehart, L.F.; Buttram, M.T.; Aurand, J.F.; Lundstrom, J.M.; Patterson, P.E.; Roose, L.D.; Crowe, W.

    1992-09-01

    Sandia National Laboratories has developed several repetitive, ultra-wideband (UWB), impulse transmitters to address impulse source, and to support experimental applications. The sources fall into two different classes, pulse peaking and pulse shorting. SNIPER (Sub-Nanosecond ImPulsE Radiator) is a source which uses an oil peaking switch to obtain a fast risetime (250-pS) pulse of 2-nS duration. The output voltage ranges between few tens of kilovolts to 250-kV. EMBL (EnantioMorphic Blumlein) is a similar device (presently under development) which uses a gas switch to short the falling portion of a 2-nS pulse to approximately 100-pS. To date, an output voltage of approximately 600-kV has been obtained (700-kV is the design goal). Depending upon the source, repetitive operation from single shot to 5-kHz (1-kHz nominal) has been obtained with excellent reliability and repeatability. Both sources are plasma switched impulse transmitters using a Hydrogen-thyratron based modulator, an oil-filled Blumlein (of two types), a peaking (or shorting) switch and a wideband TEM horn. Powers exceeding one-gigawatt are routinely generated. This technology appears to be extendable to at least 10-gigawatts. The frequency spectrum of the radiated pulse from these sources include the spectrum of 100-MHz to 3-GHz. The pulse is generated externally and then injected into the antenna. Due to the high powers involved and the need to radiate a broad spectrum of frequencies, Sandia has concentrated on TEM horn antennas. Several TEM horns have been built and used during this program. In those cases where higher gains are desired for the higher frequencies, TEM horn-fed dish antennas have been employed. A detailed overview of the UWB Transmitters along with measured radiated electric field strengths will be presented.

  19. Modeling of high-explosive driven plasma compression opening switches

    NASA Astrophysics Data System (ADS)

    Greene, A. E.; Lindemuth, I. R.; Goforth, J. H.

    The initial path of the current through a plasma compression switch is through a thin (500-nm thick) metal foil. The current explodes the foil to form the seed for the conducting plasma. The behavior of the foil at this point is the same as an exploding metal fuse for which we have a simple model. We have, therefore, chosen this model as our starting point. The fuse model assumes that the foil material is homogeneous and is characterized by a single temperature and density. The thickness of the foil is assumed to be much less than the magnetic diffusion skin depth so that the magnetic field varies linearly across the foil. For the present application we assume that the side of the foil away from the channel is fixed in space while the side by the channel is untamped. The foil/plasma will, therefore, cross the channel at the expansion velocity as the foil explodes. Equations for the electrical resistance of the foil, the magnetic fields, the motion of the foil, and the kinetic and internal energies are all solved selfconsistantly. The electrical resistivity, the pressure, and the specific energy of aluminum are taken from the Los Alamos SESAME EOS library. In the case of aluminum we have created a SESAME-style table based on the theory of More and Lee which we have modified to agree with experiment where possible.

  20. Experimental determination of gap scaling in a plasma opening switch

    NASA Astrophysics Data System (ADS)

    Black, D. C.; Commisso, R. J.; Ottinger, P. F.; Swanekamp, S. B.; Weber, B. V.

    2000-09-01

    Experiments were performed to investigate the coupling between a ˜0.5 μs conduction-time, ˜0.5 MA conduction-current plasma opening switch (POS), and an electron-beam (e-beam) diode. Electrical diagnostics provided measurements of the voltage at the oil-vacuum insulator and at the diode as well as anode and cathode currents on the generator and load sides of the POS. These measurements were combined with a flow impedance model to determine the POS gap over a range of conduction times and e-beam diode impedances, and for two POS-to-load distances. A comparison of the inferred POS gap at peak power with the critical gap for magnetic insulation indicates that the POS gap is always saturated in both switch-limited and load-limited regimes. This POS gap-size scaling with load impedance is consistent with an opening mechanism dominated by erosion and not J×B forces.

  1. Plasma flow switch experiments on Pegasus-II

    SciTech Connect

    Shlachter, J.S.; Bartsch, R.R.; Benage, J.F.

    1994-12-31

    Pegasus-II, a 4.3 MJ capacitor bank facility at Los Alamos National Laboratory, has a current rise time of 5 {mu}s and requires the use of a fast ({approx} 500 ns) opening switch with long conduction time for some applications. Development of plasma flow opening switches (PFS), based on the design of the Shiva Star experiments, has been conducted during the last year. The PFS for these experiments consisted of two components: an annular aluminum conductor bridging the gap between the coaxial conductors in the Pegasus-II power-flow channel and an annular mylar foil located 6.3 mm downstream of the aluminum. The authors have investigated assemblies with 1/r{sup 2} mass distributions, designed to produce planar motion down the power flow channel. The total mass of the PFS assembly has been varied as has the construction of the aluminum component. The downstream load in the load slot was either a high inductance, 1-cm radius non-imploding pipe or a cylindrical, 12.7-mg pure aluminum imploding foil with 5-cm radius. Experiments have been conducted both with and without a trap region in the downstream inner conductor; the trap is one mechanism for preventing PFS material from entering the load slot.

  2. Performance of plasma opening switches for the Particle Beam Fusion Accelerator II (PBFA II)

    SciTech Connect

    Rochau, G.E.; McDaniel, D.H.; Mendel, C.W.; Sweeney, M.A.; Moore, W.B.S.; Mowrer, G.R.; Simpson, W.W.; Zagar, D.M.; Grasser, T.; McDougal, C.D.

    1989-01-01

    During 1987 and 1988, Plasma Opening Switch (POS) experiments have been continued with the goal of providing voltage and power gain on the PBFA II ion beam accelerator at Sandia National Laboratories. The experiments have developed a POS that has a rugged plasma source, will open rapidly, and will couple to a high-impedance load. The initial erosion switch design with improved plasma uniformity does not couple to these loads. Therefore, we have abandoned further development of this switch for voltage and power gain. Three alternate designs have been developed, tested, and are found to have better performance with the high-impedance loads. These new switches employ magnetic fields to control and confine the injected plasma. A summary of the switch configurations, their theory of operation, and the experimental results is presented and discussed. 4 refs., 10 figs.

  3. Design of a Command-Triggered Plasma Opening Switch for Terawatt Applications

    SciTech Connect

    SAVAGE,MARK E.; MENDEL,C.W.; SEIDEL,DAVID B.

    1999-10-29

    Inductive energy storage systems can have high energy density, lending to smaller, less expensive systems. The crucial element of an inductive energy storage system is the opening switch. This switch must conduct current while energy is stored in an inductor, then open quickly to transfer this energy to a load. Plasma can perform this function. The Plasma Opening Switch (POS) has been studied for more than two decades. Success with the conventional plasma opening switch has been limited. A system designed to significantly improve the performance of vacuum opening switches is described in this paper. The gap cleared of plasma is a rough figure-of-merit for vacuum opening switches. Typical opened gaps of 3 mm are reported for conventional switches. The goal for the system described in this paper is more than 3 cm. To achieve this, the command-triggered POS adds an active opening mechanism, which allows complete separation of conduction and opening. This separation is advantageous because of the widely different time scales of conduction and opening. The detrimental process of magnetic field penetration into the plasma during conduction is less important in this switch. The opening mechanism duration is much shorter than the conduction time, so penetration during opening is insignificant. Opening is accomplished with a fast magnetic field that pushes plasma out of the switch region. Plasma must be removed from the switch region to allow high voltage. This paper describes some processes important during conduction and opening, and show calculations on the trigger requirements. The design of the switch is shown. This system is designed to demonstrate both improved performance and nanosecond output jitter at levels greater than one terawatt. An amplification mechanism is described which reduces the trigger energy. Particle-in-cell simulations of the system are also shown.

  4. Observations and implications of gap closure in plasma opening switch operation

    NASA Astrophysics Data System (ADS)

    Goyer, John R.; Kortbawi, David

    1994-09-01

    Plasma opening switches are believed to develop voltage through opening and magnetically insulating a gap formed in plasma injected between two conducting electrodes. Data will be presented to show that a relatively simple assumption about the behavior of this gap suffices to describe the overall operation of the switch. Specifically, the observed increase, then decrease, of operational voltage as a function of conduction time can be accounted for by the switch gap linearly decreasing with conduction time, while the conducted current increases. In addition to presentation of data to demonstrate this collapse, analysis is performed to couple the gap history to the voltage predicted for the switch, and to optimize this latter quantity.

  5. Implicit two-fluid simulation of electron transport in a plasma erosion opening switch

    SciTech Connect

    Mason, R.J.; Wallace, J.M.; Lee, K.

    1986-01-01

    The two-dimensional implicit code ANTHEM is used to model electron transport in Plasma Opening Switches. We look at low density (approx.4 x 10/sup 12/cm/sup -3/) switches at initial plasma temperatures as low as 5 eV. Two-fluid modeling (ions and electrons with inertia) and implicit determination of the fields is employed to allow time steps well in excess of the inverse plasma period, and cell sizes much larger than a Debye length - with the avoidance of the finite grid anomalous plasma heating characteristic of particle codes. Features indicative of both erosion and E > B plasma drift are manifest in the simulations.

  6. Space-time evolution of ejected plasma for the triggering of gas switch

    NASA Astrophysics Data System (ADS)

    Liu, Shanhong; Liu, Xuandong; Shen, Xi; Feng, Lei; Tie, Weihao; Zhang, Qiaogen

    2016-06-01

    Ejected plasma has been widely applied to the discharge process of gas spark switches as a trigger technology, and the development process of ejected plasma has a direct and important effect on the discharge characteristics of gas switches. In this paper, both the injection characteristics and space-time evolution of ejected plasma for the triggering of gas spark switch with different stored energies, pulse polarities, and pressures are studied. The discharge characteristics and breakdown process of a gas switch ignited by ejected plasma under different working coefficients are also discussed briefly. The results show that stored energy has significant influence on the characteristics of ejected plasma. With the increase of stored energy, the propulsion mode of ejected plasma in the axial direction transforms from "plasmoid" to "plasma flow," and the distribution of the ejected plasma goes through "cloud," "core-cloud," and "branch" in sequence. The velocity of ejected plasma under negative pulse polarity is obviously higher than that under positive pulse polarity, especially at the very beginning time. The radial dimensions of ejected plasma under two kinds of pulse polarities follow the similar varying pattern over time, which increase first and then decrease, assuming an inverted "U"-shaped curve. With the increase of pressure, the velocity of ejected plasma significantly decreases and the "branch" channels droop earlier. Applying the ejected plasma to the triggering of a gas switch, the switch can be triggered reliably in a much wide working coefficient range of 10%-90%. With the increase of working coefficient, the breakdown process of the switch translates from slow working mode to fast working mode, and the delay time reduces from tens of μs to hundreds of ns.

  7. Space-time evolution of ejected plasma for the triggering of gas switch

    SciTech Connect

    Liu, Shanhong Liu, Xuandong; Shen, Xi; Feng, Lei; Zhang, Qiaogen; Tie, Weihao

    2016-06-15

    Ejected plasma has been widely applied to the discharge process of gas spark switches as a trigger technology, and the development process of ejected plasma has a direct and important effect on the discharge characteristics of gas switches. In this paper, both the injection characteristics and space-time evolution of ejected plasma for the triggering of gas spark switch with different stored energies, pulse polarities, and pressures are studied. The discharge characteristics and breakdown process of a gas switch ignited by ejected plasma under different working coefficients are also discussed briefly. The results show that stored energy has significant influence on the characteristics of ejected plasma. With the increase of stored energy, the propulsion mode of ejected plasma in the axial direction transforms from “plasmoid” to “plasma flow,” and the distribution of the ejected plasma goes through “cloud,” “core-cloud,” and “branch” in sequence. The velocity of ejected plasma under negative pulse polarity is obviously higher than that under positive pulse polarity, especially at the very beginning time. The radial dimensions of ejected plasma under two kinds of pulse polarities follow the similar varying pattern over time, which increase first and then decrease, assuming an inverted “U”-shaped curve. With the increase of pressure, the velocity of ejected plasma significantly decreases and the “branch” channels droop earlier. Applying the ejected plasma to the triggering of a gas switch, the switch can be triggered reliably in a much wide working coefficient range of 10%–90%. With the increase of working coefficient, the breakdown process of the switch translates from slow working mode to fast working mode, and the delay time reduces from tens of μs to hundreds of ns.

  8. MW-scale ICRF plasma heating using IGBT switches in a multi-pulse scheme

    NASA Astrophysics Data System (ADS)

    Be'ery, I.; Kogan, K.; Seemann, O.

    2015-06-01

    Solid-state silicon switches are cheap and reliable option for 1-10 MHz RF power sources, required for plasma ion cyclotron RF heating (ICRF). The large `on' resistance of MOSFET and similar devices limits their power delivery to a few tens of kW per switch. Low resistivity devices, such as IGBT, suffer from large `off' switching time, which limits their useful frequency range and increases the power dissipated in the switch. Here we demonstrate more than 0.8 MW circulated RF power at 2 MHz using only three high voltage IGBT switches. The circuit uses the fast `on' switching capability of the IGBTs to generate high-Q pulse train. This operation mode also simplifies the measurement of RF coupling between the antenna and the plasma.

  9. Combined Flux Compression and Plasma Opening Switch on the Saturn Pulsed Power Generator

    SciTech Connect

    Felber, Franklin S.; Waisman, Eduardo M.; Mazarakis, Michael G.

    2010-05-07

    A wire-array flux-compression cartridge installed on Sandia's Saturn pulsed power generator doubled the current into a 3-nH load to 6 MA and halved its rise time to 100 ns. The current into the load, however, was unexpectedly delayed by almost 1 {mu}s. Estimates of a plasma flow switch acting as a long-conduction-time opening switch are consistent with key features of the power compression. The results suggest that microsecond-conduction-time plasma flow switches can be combined with flux compression both to amplify currents and to sharpen pulse rise times in pulsed power drivers.

  10. Combined flux compression and plasma opening switch on the Saturn pulsed power generator.

    PubMed

    Felber, Franklin S; Waisman, Eduardo M; Mazarakis, Michael G

    2010-05-07

    A wire-array flux-compression cartridge installed on Sandia's Saturn pulsed power generator doubled the current into a 3-nH load to 6 MA and halved its rise time to 100 ns. The current into the load, however, was unexpectedly delayed by almost 1 micros. Estimates of a plasma flow switch acting as a long-conduction-time opening switch are consistent with key features of the power compression. The results suggest that microsecond-conduction-time plasma flow switches can be combined with flux compression both to amplify currents and to sharpen pulse rise times in pulsed power drivers.

  11. Ultra-high-power plasma switch INPIS for pulse power systems

    NASA Technical Reports Server (NTRS)

    Lee, Ja H.; Choi, En H.; Venable, Demetrius D.; Han, Kwang S.

    1990-01-01

    A novel plasma switch, the inverse pinch switch (IN-PIS), with a combination geometry based on an inverse-pinch mechanism, has been tested and shown to alleviate the shortcomings of conventional spark gaps. The INPIS switch or INPIStron is currently being upscaled for high-voltage (approximately 1 MV) operation with a multigap arrangement similar to Sandia's rimfire electrodes used for ultra-high-voltage hold off. Preliminary results of the multigap INPIS tests at 230 kV and plasma-puff initiation methods are presented, and an application to compact pulser systems is discussed.

  12. Characterization of the plasma-switch interaction in the LBL HIF ion source

    SciTech Connect

    Hewett, D.W. ); Rutkowski, H.L. )

    1990-12-10

    A new way to characterize the performance of the LBL HIF ion source has been found. In the LBL source, ions are drawn from an arc-generated plasma reservoir in which the electrons are confined by a negative-biased switch'' mesh. Stagnation of the plasma is prevented by absorption of the excess ion flow on this mesh. The ion beam is generated by an external negative voltage that provides Child-Langmuir extraction of the ions through the switch mesh. We elucidate the physics requirements of the source and deduce switch mesh parameters needed for successful operation. 2 refs., 2 figs.

  13. Pulse power requirements for large aperture optical switches based on plasma electrode Pockels cells

    SciTech Connect

    Rhodes, M.A.; Taylor, J.

    1992-06-01

    We discuss very large-aperture optical switches (greater than 30 [times] 30 cm) as an enabling technology for inertial confinement fusion drivers based on multipass laser amplifiers. Large-scale laser fusion drivers such as the Nova laser have been based on single-pass amplifier designs in part because of the unavailability of a suitable large-aperture switch. We are developing an optical switch based on a Pockels cell employing plasma-electrodes. A plasma-electrode Pockels cell (PEPC) is a longitudinal-mode Pockels cell in which a plasma discharge is formed on each side of an electro-optic crystal (typically KDP or deuterated KDP, often designated KD*P). The plasmas formed on either side of the crystal act as transparent electrodes for a switching-pulse and are intended to allow uniform charging of the entire crystal. The switching-pulse is a nominally rectangular high-voltage pulse equal to the half-wave voltage V[sub x] ( 8 kV for KD*P or 17 kV for KDP) and is applied across the crystal via the plasma-electrodes. When the crystal is charged to V[sub x], the polarization of an incoming, linearly polarized, laser beam is rotated by 90[degree]. When used in conjunction with an appropriate, passive polarizer, an optical switch is thus realized. A switch with a clear aperture of 37 [times] 37 cm is now in construction for the Beamlet laser which will serve as a test bed for this switch as well as other technologies required for an advanced NOVA laser design. In this paper, we discuss the unique power electronics requirements of PEPC optical switches.

  14. Pulse power requirements for large aperture optical switches based on plasma electrode Pockels cells

    SciTech Connect

    Rhodes, M.A.; Taylor, J.

    1992-06-01

    We discuss very large-aperture optical switches (greater than 30 {times} 30 cm) as an enabling technology for inertial confinement fusion drivers based on multipass laser amplifiers. Large-scale laser fusion drivers such as the Nova laser have been based on single-pass amplifier designs in part because of the unavailability of a suitable large-aperture switch. We are developing an optical switch based on a Pockels cell employing plasma-electrodes. A plasma-electrode Pockels cell (PEPC) is a longitudinal-mode Pockels cell in which a plasma discharge is formed on each side of an electro-optic crystal (typically KDP or deuterated KDP, often designated KD*P). The plasmas formed on either side of the crystal act as transparent electrodes for a switching-pulse and are intended to allow uniform charging of the entire crystal. The switching-pulse is a nominally rectangular high-voltage pulse equal to the half-wave voltage V{sub x} ( 8 kV for KD*P or 17 kV for KDP) and is applied across the crystal via the plasma-electrodes. When the crystal is charged to V{sub x}, the polarization of an incoming, linearly polarized, laser beam is rotated by 90{degree}. When used in conjunction with an appropriate, passive polarizer, an optical switch is thus realized. A switch with a clear aperture of 37 {times} 37 cm is now in construction for the Beamlet laser which will serve as a test bed for this switch as well as other technologies required for an advanced NOVA laser design. In this paper, we discuss the unique power electronics requirements of PEPC optical switches.

  15. X-Band Active-Passive Rf Pulse Compressor with Plasma Switches

    SciTech Connect

    Vikharev, A.L.; Ivanov, O.A.; Gorbachev, A.M.; Lobaev, M.A.; Isaev, V.A.; Tantawi, S.G.; Lewandowski, J.R.; Hirshfield, J.L.; /Omega-P, New Haven /Yale U.

    2012-04-27

    As proposed by SLAC, the efficiency of a pulse compressor of the SLED-II type could be increased by changing both the phase of the microwave source and the coupling coefficient of the delay line. In the existing SLED-II system at frequency 11.4 GHz, the resonant delay line is coupled with the source via an iris with a constant reflection coefficient. Replacement of the iris with an active component makes it possible to create an active SLED-II system. In this paper, the use of plasma switches as the active elements is discussed. Plasma switches have been developed and tested at a high-power level for production of flattop compressed pulses. Active switching of SLED-II has demonstrated a marked increase in efficiency (by 20%) and power gain (by 37%) as compared with passive switching. The active compressor has produced 173 ns rf flattop output pulses with a power of about 112 MW.

  16. Design and experimental results on a terawatt magnetically controlled plasma opening switch

    SciTech Connect

    Savage, M.E.; Simpson, W.W.; Mendel, C.W. Jr.; McDaniel, D.H.; Levine, J.S.; Tucker, T.S.

    1998-05-01

    The magnetically controlled plasma opening switch (MCPOS) is an advanced plasma opening switch that utilizes magnetic fields to improve operation. Magnetic fields always dominate terawatt, pulsed power plasma opening switches. For that reason, the MCPOS uses controlled applied magnetic fields with magnitude comparable to the self-magnetic field of the storage inductor. One applied field holds the plasma in place while energy accumulates in the storage inductor, then another applied field pushes the plasma away from the cathode to allow energy to flow downstream. Over a ten month period, an MCPOS was designed, built, and tested on DECADE Module 2 at Physics International. The peak drive current was 1.8 MA in 250 ns. The output parameters were up to 1 MA into an electron beam load. The radiation temporal pulse width averaged 60 nanoseconds full-width at half-maximum. The peak load voltage ranged from one to two megavolts. The experiments demonstrated efficient power flow through a long, low-impedance magnetically insulated transmission line between the magnetically controlled plasma opening switch and the load.

  17. High Voltage, Fast-Switching Module for Active Control of Magnetic Fields and Edge Plasma Currents

    NASA Astrophysics Data System (ADS)

    Ziemba, Timothy; Miller, Kenneth; Prager, James; Slobodov, Ilia

    2016-10-01

    Fast, reliable, real-time control of plasma is critical to the success of magnetic fusion science. High voltage and current supplies are needed to mitigate instabilities in all experiments as well as disruption events in large scale tokamaks for steady-state operation. Silicon carbide (SiC) MOSFETs offer many advantages over IGBTs including lower drive energy requirements, lower conduction and switching losses, and higher switching frequency capabilities; however, these devices are limited to 1.2-1.7 kV devices. As fusion enters the long-pulse and burning plasma eras, efficiency of power switching will be important. Eagle Harbor Technologies (EHT), Inc. developing a high voltage SiC MOSFET module that operates at 10 kV. This switch module utilizes EHT gate drive technology, which has demonstrated the ability to increase SiC MOSFET switching efficiency. The module will allow more rapid development of high voltage switching power supplies at lower cost necessary for the next generation of fast plasma feedback and control. EHT is partnering with the High Beta Tokamak group at Columbia to develop detailed high voltage module specifications, to ensure that the final product meets the needs of the fusion science community.

  18. Current Propagation Between a Plasma Opening Switch and a Load During Opening

    DTIC Science & Technology

    2001-06-01

    where the plasma was flowing through a 90o bend. The electron density was about 1015 cm-3 in the gap. The plasma was generated by a surface flashover ...CURRENT PROPAGATION BETWEEN A PLASMA OPENING SWITCH AND A LOAD DURING OPENING G.I. Dolgachev, Yu.G. Kalinin, A.S. Kingsep, A.G...Ushakov Russian Research Center �Kurchatov Institute�, Moscow 123182, Russia R.J. Commisso, P.F. Ottinger, S.B. Swanekamp, B.V. Weber Plasma Physics

  19. Research on 2x1 plasma electrode electro-optical switch with large aperture

    NASA Astrophysics Data System (ADS)

    Zhang, Xiong Jun; Zheng, Kui Xing; Feng, B.; Wu, D. S.; Lu, J. P.; Tian, X. L.; Jin, F.; Sui, Zhan; Wei, Xiaofeng; Zhang, Xiaomin

    2005-01-01

    In conceptual design of the prototype for SG-III facility, a full aperture electro-optical switch was placed between the cavity mirror and the main amplifier to isolate the reflected beams. The beam on the cavity mirror is 240mm×240mm square. Pockells cells of conversional design with coaxial ring electrodes can not scale to such large square aperture. In the 1980s, a plasma electrode Pockels cell (PEPC) concept was invented at LLNL. It uses transparent plasma electrode formed through gas discharge as the electrodes to apply the voltage across switching crystal to rotate the polarization of a transmitted laser beam. And it can be scaled to large aperture with thin crystal. So the switch which would be used in SG-III is based on this technology. The technical integration line as a prototype of SG-III laser is actually a 4×2 beam bundle. And the full aperture optical switch is mechanically designed four apertures as a removable unit, and electrically two 2×1 PEPC putting together. So we built a 2×1 PEPC to develop the technology first. The 2×1 PEPC is a sandwich structure made of an insulating mid plane between a pair of plasma chambers. The frame of both plasma chambers are machining in duralumin. Each chamber is installed with a planar magnetic cathode and four segments spherical anodes made from stainless steel. The cathode and anode are insulated from the housing with a special shell made from plastic, and plasma is insulated from the housing by an 80-μm-thick anodic coating on the duralumin. The two plasma chambers are separated by a mid plane of glass frame with two square holes. The two holes are filled by two electro-optical crystals with a 240-mm square aperture. With the optimized operating pressure and the electrical parameters, a very good homogeneity and low resistivity plasma electrode is obtained. Finally we tested its switching performance to simulate the case that it will be used in the SG-III prototype facility. It works with a quarter wave

  20. Plasma density evolution in plasma opening switch obtained by a time-resolved sensitive He-Ne interferometer

    NASA Astrophysics Data System (ADS)

    Chen, Lin; Ren, Jing; Guo, Fan; Zhou, LiangJi; Li, Ye; He, An; Jiang, Wei

    2014-03-01

    To understand the formation process of vacuum gap in coaxial microsecond conduction time plasma opening switch (POS), we have made measurements of the line-integrated plasma density during switch operation using a time-resolved sensitive He-Ne interferometer. The conduction current and conduction time in experiments are about 120 kA and 1 μs, respectively. As a result, more than 85% of conduction current has been transferred to an inductive load with rise time of 130 ns. The radial dependence of the density is measured by changing the radial location of the line-of-sight for shots with the same nominal POS parameters. During the conduction phase, the line-integrated plasma density in POS increases at all radial locations over the gun-only case by further ionization of material injected from the guns. The current conduction is observed to cause a radial redistribution of the switch plasma. A vacuum gap forms rapidly in the plasma at 5.5 mm from the center conductor, which is consistent with the location where magnetic pressure is the largest, allowing current to be transferred from the POS to the load.

  1. Frequency-resolved optical gating for characterization of VUV pulses using ultrafast plasma mirror switching.

    PubMed

    Itakura, Ryuji; Kumada, Takayuki; Nakano, Motoyoshi; Akagi, Hiroshi

    2015-05-04

    We propose and experimentally demonstrate a method for characterizing vacuum ultraviolet (VUV) pulses based on time-resolved reflection spectroscopy of fused silica pumped by an intense laser pulse. Plasma mirror reflection is used as an ultrafast optical switch, which enables us to measure frequency-resolved optical gating (FROG) traces. The VUV temporal waveform can be retrieved from the measured FROG trace using principal component generalized projections algorithm with modification. The temporal profile of the plasma mirror reflectivity is also extracted simultaneously.

  2. Magnetic Piston Propagation in a 100-ns Plasma Opening Switch

    NASA Astrophysics Data System (ADS)

    Weingarten, A.; Grabowski, C.; Chakrabarti, N.; Maron, Y.; Fruchtman, A.

    1998-11-01

    The propagation of a magnetic piston through the plasma of a 90-ns, 170-kA POS is observed by studying the electron density, magnetic field, and ion velocity evolution. For the prefilled plasma n_e=(2.2± 0.5)× 10^14 cm-3, and T_e=5.5± 1 eV. The plasma composition is studied from absolute line intensities and collisional-radiative calculations. Most of the plasma ions are protons (90% near the cathode) with the rest being mainly CIV. The Hall-MHD conditions are not fulfilled for our experiment and ion motion is significant. The 3D-resolved ne evolution during the current pulse is studied from the line intensities of ions doped in the plasma using laser evaporation, and the magnetic field from Zeeman splitting. A diagonal magnetic piston propagates from the generator towards the load at about half the proton Alfven velocity. The protons are specularly reflected by the piston, while the heavy ions cross the potential hill in the piston, acquiring a lower velocity. The proton reflection causes an increase of ne ahead of the piston, followed by a sharp (10-20 ns) and substantial drop in ne (to 10-50% from the initial value). The magnetic field distribution studied using chordal observation, and theoretical analysis of ne and the magnetic field evolution are presented.

  3. Cyclic resistive switching effect in plasma electrolytically oxidized mesoporous Pt/TiO2 structures

    NASA Astrophysics Data System (ADS)

    Fullam, S.; Ray, N. J.; Karpov, E. G.

    2015-06-01

    Understanding the resistive switching phenomenon in metal oxide semiconductors is necessary in producing reliable resistive random access memory and other variable resistance devices. An alternative technique for fabricating resistive switching elements is presented. Using plasma electrolytic oxidation, 10-11 μ m thick oxide layers were galvanostatically grown on Ti substrates in a 3 M H2SO4 electrolyte. Analysis of the TiO2 layer by SEM, AFM, and XRD found the mesoporous titania surface to have a high ratio of rutile to anatase phases. The samples demonstrated pinched I-V hysteresis attributed to the resistive switching effect, when subjected to cyclic loading (±2.5, 1.6, 0.7 V; 23-736 μ Hz) at room temperature. Ratio with magnitude of 6 is reported for the resistance switching effect during 1.6 V 368 μ Hz loads.

  4. Theoretical and computational studies of magnetic insulation and other plasma-opening-switch phenomena

    NASA Astrophysics Data System (ADS)

    Lindeman, Erick L., Jr.

    1989-11-01

    The following topics are discussed: electron trajectories and magnetic insulation; blade-load simulation studies; azimuthal asymmetries; MAGIC simulation studies of a segmented plasma opening switch; PBFA II calculations with different spatial resolution; and analytic solution of the electron current layer in the magnetic front.

  5. Performance of magnetically injected plasma opening switches for the Particle Beam Fusion Accelerator 2 (PBFA 2)

    SciTech Connect

    Rochau, G.E.; McDaniel, D.H.; Mendel, C.W. Jr.; Sweeney, M.A.; Moore, W.B.S.; Mowrer, G.R.; Simpson, W.W.; Zagar, D.M.

    1990-01-01

    Plasma opening switch experiments using a magnetically injected plasma have been in progress since October 1988. Plasma densities of 1 {times} 10{sup 12} to 2 {times} 10{sup 13} e/cm{sup 3} have been injected from the anode side into the 8 cm gap of the 20 ohm magnetically insulated transmission line of PBFA II using a slowly rising B{sub r,z} magnetic field. This field confines the azimuthally-uniform plasma to produce switches up to 30 cm in length. Four MIP geometries have been investigated to find a higher electrical impedance when the switch opens. These studies have shown that a separation of 10 to 20 cm from the load is important to keep the POS from affecting the load performance. With such a separation, 20 to 30 TW of power at 7 to 11 MV has been delivered to electron and ion diode loads. Data on switch performance with various loads and factors that improve performance are discussed. 4 refs., 6 figs.

  6. Self-induced gaseous plasma as high power microwave opening switch medium

    SciTech Connect

    Lin, S.; Beeson, S.; Dickens, J.; Neuber, A.; Liu, C.

    2015-04-15

    Self-induced gaseous plasma is evaluated as active opening switch medium for pulsed high power microwave radiation. The self-induced plasma switch is investigated for N{sub 2} and Ar environments under pressure conditions ranging from 25 to 700 Torr. A multi-pass TE{sub 111} resonator is used to significantly reduce the delay time inherently associated with plasma generation. The plasma forms under the pulsed excitation of a 4 MW magnetron inside the central dielectric tube of the resonator, which isolates the inner atmospheric gas from the outer vacuum environment. The path from the power source to the load is designed such that the pulse passes through the plasma twice with a 35 ns delay between these two passes. In the first pass, initial plasma density is generated, while the second affects the transition to a highly reflective state with as much as 30 dB attenuation. Experimental data revealed that virtually zero delay time may be achieved for N{sub 2} at 25 Torr. A two-dimensional fluid model was developed to study the plasma formation times for comparison with experimental data. The delay time predicted from this model agrees well with the experimental values in the lower pressure regime (error < 25%), however, due to filamentary plasma formation at higher pressures, simulated delay times may be underestimated by as much as 50%.

  7. Anode Sheath Switching in a Carbon Nanotube Arc Plasma

    SciTech Connect

    Abe Fetterman, Yevgeny Raitses, and Michael Keidar

    2008-04-08

    The anode ablation rate is investigated as a function of anode diameter for a carbon nanotube arc plasma. It is found that anomalously high ablation occurs for small anode diameters. This result is explained by the formation of a positive anode sheath. The increased ablation rate due to this positive anode sheath could imply greater production rate for carbon nanotubes.

  8. Ion Current Collection Diagnostic for the Triggered Plasma Opening Switch Experiment

    NASA Astrophysics Data System (ADS)

    Jackson, D. P.; Gilmore, M. A.

    2005-10-01

    The novel Triggered Plasma Opening Switch (TPOS) is a unique device that exploits the high conductivity and low mass properties of plasma. The TPOS's objective is to take the initial ˜.8 MA (˜250 ns rise time) storage inductor current and deliver ˜.5 MA at ˜2.5 MV (˜10ns rise time) to a load of ˜5-10 φ. Study of the TPOS characteristics is in progress via an Ion Current Collection Diagnostic (ICCD). The ICCD has been designed, fabricated, tested, and is in use on the TPOS in order to explore the main switch opening profile. The ICCD utilizes 12 charge collectors (biased faraday cups) that are positioned perpendicularly to the main switch stage in order to collect radially traveling ions emitted from the plasma surface via the Child-Langmuir law. Magnetostatic simulations with self consistent space charge emitting surfaces of the main switch using the Trak static 2D finite element code have been conducted as well. Finally, ICCD experimental data have been recorded, and hopefully these data will provide evidence that support both theory and simulation.

  9. Opening Switch Research on a Plasma Focus VI.

    DTIC Science & Technology

    1988-02-26

    and Control Nucl. Fusion Res., 121 (IAEA, Vienna, 1969). 35. V. F. D’yachenko and V. S. Imshennik, Sov . Phys . JETP 29, 947 (1969). 36. D. E. Potter...20. Phys . JETP Lett . 15, 232 (1972). 20. K. Boulais, G. Gerdin, and F. Venneri, Bult. Amer. Phys . Soc. 31, 1456 (1986). 21. F. Venneri, H. Krompholz...IAEA, 1985 ). 8. T. Oppenlaender, G. Pross, G. Decker and M. Truck, Plasma Phys . 19, 1075 (1977). 9. D. L. Jassby, Trans. Amer. Nucl. Soc. 30, 61

  10. Opening switch research on a dense plasma focus

    NASA Astrophysics Data System (ADS)

    Gerdin, G.

    1987-02-01

    Experiments were performed to enhance power coupling to the load by placing the load electrode opposite the muzzle end of the Dense Plasma Focus plasma gun. The impaler concept, whereby the current sheath is run into a knife edge insulator, was tested in two configurations. However, the power coupled to the load was always less than one tenth that of the experiments where the load was coupled to the breach of the gun. Other load coupling schemes where the load electrode was brought near the outside of the central electrode prevented pinches (voltage surges) when placed too close and the power coupled to the load was reduced when the load electrodes were moved away. The results were not as good as those of the impaler concept. Measurements of the dynamics of the current sheath in various stages were performed and compared with theory. Generally the velocity of the current sheath falls below theoretical expectations suggesting the presence of electrode drag, a phenomenon not present in the model. During the radial collapse phase the model and the experimental estimates of dL/dt are in substantiaL agreement before pinch time but disagree afterward due to two dimensional effects not present in the theory.

  11. Note: Design and investigation of a multichannel plasma-jet triggered gas switch.

    PubMed

    Tie, Weihao; Liu, Xuandong; Zhang, Qiaogen; Liu, Shanhong

    2014-07-01

    We described the fabrication and testing of a multichannel plasma-jet triggered gas switch (MPJTGS). A novel six-channel annular micro-plasma-gun was embedded in the trigger electrode to generate multichannel plasma jets as a nanosecond trigger pulse arrived. The gas breakdown in multiple sites of the spark gap was induced and fixed around jet orifices by the plasma jets. We tested the multichannel discharge characteristics of the MPJTGS in two working modes with charge voltage of 50 kV, trigger voltage of +40 kV (25 ns rise time), and trigger energy of 240 J, 32 J, and 2 J, respectively, at different working coefficients. Results show that the average number of discharge channels increased as the trigger energy increased, and decreased as the working coefficient decreased. At a working coefficient of 87.1% and trigger energy of 240 J, the average number of discharge channels in Mode II could reach 4.1.

  12. Outlook for the use of microsecond plasma opening switches to generate high-power nanosecond current pulses

    NASA Astrophysics Data System (ADS)

    Dolgachev, G. I.; Maslennikov, D. D.; Ushakov, A. G.

    2006-12-01

    An analysis is made of the current break process in microsecond plasma opening switches and their possible application in high-current generators. Necessary conditions are determined for generating megavolt pulses in the erosion mode of a plasma opening switch with the gap insulated by an external magnetic field. Under these conditions, efficient sharpening of high-power submegampere current pulses can be achieved. The possibility of using plasma opening switches operating at voltages of 5 6 MV to generate X-ray and gamma emission is discussed. The main operating and design parameters of a six-module plasma opening switch with a current pulse amplitude of 3.7 MA and voltage of 4 6 MV for use in the MOL generator, which is the prototype of one of the 24 modules of the projected Baikal multimegajoule generator, are estimated by using the available scalings.

  13. 20 kA PFN capacitor bank with solid-state switching. [pulse forming network for plasma studies

    NASA Technical Reports Server (NTRS)

    Posta, S. J.; Michels, C. J.

    1973-01-01

    A compact high-current pulse-forming network capacitor bank using paralleled silicon controlled rectifiers as switches is described. The maximum charging voltage of the bank is 1kV and maximum load current is 20 kA. The necessary switch equalization criteria and performance with dummy load and an arc plasma generator are described.

  14. Zero voltage switching driver and flyback transformer for generation of atmospheric pressure plasma jet

    NASA Astrophysics Data System (ADS)

    Zin, Rosnah Mohd; Soon, Chin Fhong; Sani, Mohd Zuhri Ab; Rizon, Elfa Rizan; Tee, Kian Sek; Ahmad, Mohd Khairul; Ahmad, Nabihah@Nornabihah; Jubadi, Warsuzarina Mat; Nayan, Nafarizal

    2017-09-01

    There are increasing interests in the application of cold atmospheric plasma device for the application in surface science and medical field. Numerous studies focused on the effects of plasma emission onto living organisms. This report presents the application of a power driver circuit for induction of cold atmospheric plasma (CAP). The system consists of a resonant inverter of Zero Voltage Switching (ZVS) circuit powered by a 12Vdc input voltage which is coupled to a flyback transformer in generation of high voltage up to 24.5 kV. The output voltage from the ZVS driver and flyback transformer to the plasma torch (quartz tube) was determined using Falstad circuit simulation. The simulation on the waveforms generated from the ZVS circuit correlated well with the actual voltage measurement at the output of the ZVS circuit. The peak voltage dropped across a parallel capacitor coupled to the flyback transformer is approximately 36 V. The atmospheric pressure plasma jet (APPJ) purged with Argon gas at a flow rate of 50 l/min was exposed to a leaf for 5 seconds. This created pin holes in the exposed area of the leaf indicating high temperature was induced at the focused spot of the plasma. An atmospheric pressure plasma jet (APPJ) system has been developed for with potential application in destructive medicine.

  15. Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch.

    PubMed

    Muto, Akihiko; Ochiai, Kyoko; Kimura, Yoshitaka; Itoh-Nakadai, Ari; Calame, Kathryn L; Ikebe, Dai; Tashiro, Satoshi; Igarashi, Kazuhiko

    2010-12-01

    Two transcription factors, Pax5 and Blimp-1, form a gene regulatory network (GRN) with a double-negative loop, which defines either B-cell (Pax5 high) or plasma cell (Blimp-1 high) status as a binary switch. However, it is unclear how this B-cell GRN registers class switch DNA recombination (CSR), an event that takes place before the terminal differentiation to plasma cells. In the absence of Bach2 encoding a transcription factor required for CSR, mouse splenic B cells more frequently and rapidly expressed Blimp-1 and differentiated to IgM plasma cells as compared with wild-type cells. Genetic loss of Blimp-1 in Bach2(-/-) B cells was sufficient to restore CSR. These data with mathematical modelling of the GRN indicate that Bach2 achieves a time delay in Blimp-1 induction, which inhibits plasma cell differentiation and promotes CSR (Delay-Driven Diversity model for CSR). Reduction in mature B-cell numbers in Bach2(-/-) mice was not rescued by Blimp-1 ablation, indicating that Bach2 regulates B-cell differentiation and function through Blimp-1-dependent and -independent GRNs.

  16. Switching antipsychotics to aripiprazole or blonanserin and plasma monoamine metabolites levels in patients with schizophrenia.

    PubMed

    Miura, Itaru; Shiga, Tetsuya; Katsumi, Akihiko; Kanno-Nozaki, Keiko; Mashiko, Hirobumi; Niwa, Shin-Ichi; Yabe, Hirooki

    2014-03-01

    Blonanserin is a novel atypical antipsychotic drug that has efficacy equal to risperidone. We investigated the effects of aripiprazole and blonanserin on clinical symptoms and plasma levels of homovanillic acid (pHVA) and 3-methoxy-4hydroxyphenylglycol in the switching strategy of schizophrenia. Twenty two Japanese patients with schizophrenia were enrolled into this open study. The antipsychotics of all patients were switched to aripiprazole or blonanserin for the improvement of clinical symptoms or side effects. Plasma monoamine metabolites levels were analyzed with high-performance liquid chromatography. There were no significant effects for time (p = 0.346) or time × group interaction (p = 0.27) on the changes of positive and negative syndrome scale (PANSS) total score, although blonanserin decreased PANSS scores. We observed negative correlation between pHVA at baseline and the change in PANSS total score (rs = -0.450, p = 0.046). We also found positive correlation between the changes in pHVA and the changes in PANSS total (rs = 0.536, p = 0.015) and positive (rs = 0.572, p = 0.008) scores. There were no differences between blonanserin and aripiprazole in the improvement of clinical symptoms. Our results suggest that pHVA may be useful indicator for the switching strategy to aripiprazole or blonanserin in schizophrenia. Copyright © 2014 John Wiley & Sons, Ltd.

  17. High voltage, high power operation of the plasma erosion opening switch

    SciTech Connect

    Neri, J.M.; Boller, J.R.; Ottinger, P.F.; Weber, B.V.; Young, F.C.

    1987-04-07

    A Plasma Erosion Opening Switch (PEOS) is used as the opening switch for a vacuum inductive storage system driven by a 1.8-MV, 1.6-TW pulsed power generator. A 135-nH vacuum inductor is current charged to approx.750 kA in 50 ns through the closed PEOS which then opens in <10 ns into an inverse ion diode load. Electrical diagnostics and nuclear activations from ions accelerated in the diode yield a peak load voltage (4.25 MV) and peak load power (2.8 TW) that are 2.4 and 1.8 times greater than ideal matched load values for the same generator pulse.

  18. Active microwave pulse compressors employing oversized resonators and distributed plasma switches

    SciTech Connect

    Vikharev, A. L.; Gorbachev, A. M.; Ivanov, O. A.; Isaev, V. A.; Kusikov, S. V.; Kolysko, A. L.; Litvak, A. G.; Petelin, M. I.; Hirshfield, J. L.

    1999-07-12

    Principles and preliminary design considerations for microwave pulse compressors using electrically-switched Bragg reflectors were presented by Petelin, Vikharev and Hirshfield at AAC'96. This paper presents results of experiments to study performance of several proto-type designs of such compressors. In moderate-power tests using a plasma-switched TE{sub 011} cavity as the active element, a 25 nsec, 1.8 MW output pulse was realized, corresponding to a peak power gain of 20:1, with an energy efficiency of 30%. A high-power prototype of a 60% energy efficient compressor is under construction that is designed to yield a 100 nsec. 100 MW output pulse with a peak power gain of 17:1. Details of this design are described.

  19. Active microwave pulse compressors employing oversized resonators and distributed plasma switches

    SciTech Connect

    Vikharev, A.L.; Gorbachev, A.M.; Ivanov, O.A.; Isaev, V.A.; Kusikov, S.V.; Kolysko, A.L.; Litvak, A.G.; Petelin, M.I.; Hirshfield, J.L.

    1999-07-01

    Principles and preliminary design considerations for microwave pulse compressors using electrically-switched Bragg reflectors were presented by Petelin, Vikharev and Hirshfield at AAC{close_quote}96 (1). This paper presents results of experiments to study performance of several proto-type designs of such compressors. In moderate-power tests using a plasma-switched TE{sub 011} cavity as the active element, a 25 nsec, 1.8 MW output pulse was realized, corresponding to a peak power gain of 20:1, with an energy efficiency of 30{percent}. A high-power prototype of a 60{percent} energy efficient compressor is under construction that is designed to yield a 100 nsec. 100 MW output pulse with a peak power gain of 17:1. Details of this design are described. {copyright} {ital 1999 American Institute of Physics.}

  20. Determination of famotidine in human plasma by high performance liquid chromatography with column switching.

    PubMed

    Zhong, L; Yeh, K C

    1998-02-01

    A rapid, sensitive and robust reverse-phase high performance liquid chromatographic (HPLC) method with column switching and an internal standard for the quantitative determination of famotidine in human plasma is described. Famotidine and the internal standard were isolated from plasma samples by cation exchange solid phase extraction with SCX cartridges. The chromatographic separation was accomplished by an Inertsil C4 column with a mobile phase of acetonitrile/phosphate aqueous solution, connected by a switching valve to a BDS Hypersil C8 column with a mobile phase of acetonitrile/sodium dodecyl sulfate and phosphate aqueous solution. UV detection was set at 267 nm. The standard curve was linear in the concentration range of 1-100 ng ml-1. The intraday coefficients of variation at all concentration levels were less than 10%. The interday consistency was assessed by running QC samples during each daily run. The limit of quantification for famotidine in human plasma was 1 ng ml-1. The method has been utilized to support clinical pharmacokinetic studies in healthy volunteers who received famotidine 10 mg orally.

  1. Switched ferroelectric plasma ionizer (SwiFerr) for ambient mass spectrometry.

    PubMed

    Neidholdt, Evan L; Beauchamp, J L

    2011-01-01

    We present the implementation of a switched ferroelectric plasma ionizer (SwiFerr) for ambient analysis of trace substances by mass spectrometry. The device utilizes the ferroelectric properties of barium titanate (BaTiO(3)) to take advantage of the high electric field resulting from polarization switching in the material. The source comprises a [001]-oriented barium titanate crystal (5 × 5 × 1 mm) with a metallic rear electrode and a metallic grid front electrode. When a high voltage AC waveform is applied to the rear electrode to switch polarization, the resulting electric field on the face of the crystal promotes electron emission and results in plasma formation between the crystal face and the grounded grid at ambient pressure. Interaction with this plasma and the resulting reagent ions effects ionization of trace neutrals. The source requires less than 1 W of power to operate under most circumstances, ionizes molecules with acidic and basic functional groups easily, and has proven quite versatile for ambient analysis of both vapor phase and aspirated powdered solid samples. Ionization of vapor phase samples of the organics triethylamine, tripropylamine, tributylamine, and pyridine results in observation of the singly protonated species in the positive ion mass spectrum with sensitivity extending into the high ppb range. With acetic acid, deprotonated clusters dominate the negative ion mass spectrum. Aerodynamic sampling of powdered samples is used to record mass spectra of the pharmaceuticals loperamide and ibuprofen. Chemical signatures, including protonated loperamide and deprotonated ibuprofen, are observed for each drug. The robust, low power source lends itself easily to miniaturization and incorporation in field-portable devices used for the rapid detection and characterization of trace substances and hazardous materials in a range of different environments.

  2. Observations of two-dimensional magnetic field evolution in a plasma opening switch

    NASA Astrophysics Data System (ADS)

    Shpitalnik, R.; Weingarten, A.; Gomberoff, K.; Krasik, Ya.; Maron, Y.

    1998-03-01

    The time dependent magnetic field distribution was studied in a coaxial 100-ns positive-polarity Plasma Opening Switch (POS) by observing the Zeeman effect in ionic line emission. Measurements local in three dimensions are obtained by doping the plasma using laser evaporation techniques. Fast magnetic field penetration with a relatively sharp magnetic field front (⩽1 cm) is observed at the early stages of the pulse (t≲25). Later in the pulse, the magnetic field is observed at the load-side edge of the plasma, leaving "islands" of low magnetic field at the plasma center that last for about 10 ns. The two-dimensional (2-D) structure of the magnetic field in the r,z plane is compared to the results of an analytical model based on electron-magneto-hydrodynamics, that utilizes the measured 2-D plasma density distribution and assumes fast magnetic field penetration along both POS electrodes. The model results provide quantitative explanation for the magnetic field evolution observed.

  3. Biliopancreatic diversion with duodenal switch modifies plasma chemerin in early and late post-operative periods.

    PubMed

    Parlee, Sebastian D; Wang, Yan; Poirier, Paul; Lapointe, Marc; Martin, Julie; Bastien, Marjorie; Cianflone, Katherine; Goralski, Kerry B

    2015-06-01

    Bariatric surgery remains the most effective treatment for obesity and metabolic syndrome. Surgical benefit arises from early-phase resolution of hyperglycemia and late-phase weight loss. The adipokine chemerin is of interest given its roles in immunity, adipogenesis, and metabolism. The study objective was to examine the effects of biliopancreatic diversion with duodenal switch (BPD-DS) on plasma chemerin in the early and late post-operative stages. 83 adults with obesity undergoing BPD-DS, 45 obese non-surgical controls, and 9 lean surgical controls were enrolled. Plasma parameters and anthropometric measures were obtained at baseline and at, early (24 h, 5 D) and late (6 months and 12 months) post-operative stages. Plasma chemerin dropped from 176±49 ng/mL at baseline to 132±52 ng/mL 24 h after BPD-DS, rebounded to 200±66 ng/mL after 5 D, and declined to 124±51 and 110±34 ng/mL after 6 and 12 months. Plasma chemerin correlated negatively with measures of inflammation and hepatic injury and positively with measures of obesity, metabolic syndrome, and inflammation in the early and late post-operative periods, respectively. Chemerin has a novel role in surgical injury but not hyperglycemia resolution early after BPD-DS. Over the long term, plasma chemerin declines to a new set point that is partially determined by body fat reductions. © 2015 The Obesity Society.

  4. A study of parameters useful for describing plasma-opening switches

    SciTech Connect

    Mendel, C.W. Jr.; Seidel, D.B.; Rosenthal, S.E.

    1998-09-01

    Plasma opening switches (POS) have been used continually and studied since their introduction in 1975. During that period they have performed well for prepulse suppression and sharpening the front of the power pulse. Their use for long conduction time and rapid opening to stand off high voltage in the same POS has met with very limited success. There has been a large theoretical effort involving models and particle-in-cell simulations (PICS), but the connection between theory and experiment has been tenuous at best, and convincing agreement with experiment has been minimal. The authors believe progress toward long conduction and rapid opening would be faster if macroscopic physical parameters describing the physics of the switch were used to compare experiment to simulation. One of these parameters (electron flow impedance) has been used to describe the electrical characteristics of the POS. This parameter provides a good description of both the standard POS (SPOS) and the magnetically controlled POS (MCPOS) because its value is sensibly independent of load current. An additional parameter, the effective mass of the plasma, was measured in one MCPOS experiment. In this article they describe other parameters important to operation of the SPOS and the MCPOS, and parameters important in designing PICS used to study these devices.

  5. A Tesla-pulse forming line-plasma opening switch pulsed power generator

    NASA Astrophysics Data System (ADS)

    Novac, B. M.; Kumar, R.; Smith, I. R.

    2010-10-01

    A pulsed power generator based on a high-voltage Tesla transformer which charges a 3.85 Ω/55 ns water-filled pulse forming line to 300 kV has been developed at Loughborough University as a training tool for pulsed power students. The generator uses all forms of insulation specific to pulsed power technology, liquid (oil and water), gas (SF6), and magnetic insulation in vacuum, and a number of fast voltage and current sensors are implemented for diagnostic purposes. A miniature (centimeter-size) plasma opening switch has recently been coupled to the output of the pulse forming line, with the overall system comprising the first phase of a program aimed at the development of a novel repetitive, table-top generator capable of producing 15 GW pulses for high power microwave loads. Technical details of all the generator components and the main experimental results obtained during the program and demonstrations of their performance are presented in the paper, together with a description of the various diagnostic tools involved. In particular, it is shown that the miniature plasma opening switch is capable of reducing the rise time of the input current while significantly increasing the load power. Future plans are outlined in the conclusions.

  6. Effects of plasma treatment time on surface characteristics of indium-tin-oxide film for resistive switching storage applications

    NASA Astrophysics Data System (ADS)

    Chen, Po-Hsun; Chang, Ting-Chang; Chang, Kuan-Chang; Tsai, Tsung-Ming; Pan, Chih-Hung; Shih, Chih-Cheng; Wu, Cheng-Hsien; Yang, Chih-Cheng; Chen, Wen-Chung; Lin, Jiun-Chiu; Wang, Ming-Hui; Zheng, Hao-Xuan; Chen, Min-Chen; Sze, Simon M.

    2017-08-01

    In this paper, we implement a post-oxidation method to modify surface characteristics of indium tin oxide (ITO) films by using an O2 inductively coupled plasma (ICP) treatment. Based on field emission-scanning electron microscope (FE-SEM) and atomic force microscope (AFM) analysis, we found that the surface morphologies of the ITO films become slightly flatter after the O2 plasma treatment. The optical characteristics and X-ray diffraction (XRD) experiments of either pure ITO or O2 plasma treated ITO films were also verified. Even though the XRD results showed no difference from bulk crystallizations, the oxygen concentrations increased at the film surface after O2 plasma treatment, according to the XPS inspection results. Moreover, this study investigated the effects of two different plasma treatment times on oxygen concentration in the ITO films. The surface sheet resistance of the plasma treated ITO films became nearly non-conductive when measured with a 4-point probe. Finally, we applied the O2 plasma treated ITO films as the insulator in resistive random access memory (RRAM) to examine their potential for use in resistive switching storage applications. Stable resistance switching characteristics were obtained by applying the O2 plasma treatment to the ITO-based RRAM. We also confirmed the relationship between plasma treatment time and RRAM performance. These material analyses and electrical measurements suggest possible advantages in using this plasma treatment technique in device fabrication processes for RRAM applications.

  7. Gap formation processes in a high-density plasma opening switch

    NASA Astrophysics Data System (ADS)

    Grossmann, J. M.; Swanekamp, S. B.; Ottinger, P. F.; Commisso, R. J.; Hinshelwood, D. D.; Weber, B. V.

    1995-01-01

    A gap opening process in plasma opening switches (POS) is examined with the aid of numerical simulations. In these simulations, a high density (ne=1014-5×1015 cm-3) uniform plasma initially bridges a small section of the coaxial transmission line of an inductive energy storage generator. A short section of vacuum transmission line connects the POS to a short circuit load. The results presented here extend previous simulations in the ne=1012-1013 cm-3 density regime. The simulations show that a two-dimensional (2-D) sheath forms in the plasma near a cathode. This sheath is positively charged, and electrostatic sheath potentials that are large compared to the anode-cathode voltage develop. Initially, the 2-D sheath is located at the generator edge of the plasma. As ions are accelerated out of the sheath, it retains its original 2-D structure, but migrates axially toward the load creating a magnetically insulated gap in its wake. When the sheath reaches the load edge of the POS, the POS stops conducting current and the load current increases rapidly. At the end of the conduction phase a gap exists in the POS whose size is determined by the radial dimensions of the 2-D sheath. Simulations at various plasma densities and current levels show that the radial size of the gap scales roughly as B/ne, where B is the magnetic field. The results of this work are discussed in the context of long-conduction-time POS physics, but exhibit the same physical gap formation mechanisms as earlier lower density simulations more relevant to short-conduction-time POS.

  8. MHD-to-PIC transition for modeling of conduction and opening in a plasma opening switch

    NASA Astrophysics Data System (ADS)

    Schumer, J. W.

    2001-06-01

    The plasma opening switch (POS) is a critical element of some inductive-energy-storage pulsed-power generators. Detailed understanding of plasma redistribution and thinning during the POS conduction phase can be gained through magnetohydrodynamic fluid (MHD) simulations. As space-charge separation and kinetic effects become important late in the conduction phase (beginning of the opening phase), MHD methods become invalid and particle-in-cell (PIC) methods should be used. In this article, the applicability of MHD techniques is extended into PIC-like regimes by including non-ideal MHD phenomena such as the Hall effect and resistivity. The feasibility of the PIC technique is likewise extended into high-density, low-temperature MHD-like regimes by using a novel numerical cooling algorithm. At an appropriate time, an MHD-to-PIC transition must be accomplished in order to accurately simulate the POS opening phase. The mechanics for converting MHD (MACH2) output into PIC (MAGIC2d) input are introduced, as are the transition criteria determining when to perform this conversion. To establish these transition criteria, side-by-side MHD and PIC simulations are presented and compared. These separate simulations are then complemented by a proof-of-principle MHD-to-PIC transition, thereby demonstrating this MHD-to-PIC technique as a potentially viable tool for the simulation of POS plasmas. Practical limitations of the MHD-to-PIC transition method and applicability of the transition criteria to hybrid fluid-kinetic simulations are discussed.

  9. High-Power Plasma Switch for 11.4 GHz Microwave Pulse Compressor

    SciTech Connect

    Jay L. Hirshfield

    2010-03-04

    Results obtained in several experiments on active RF pulse compression at X-band using a magnicon as the high-power RF source are presented. In these experiments, microwave energy was stored in high-Q TE01 and TE02 modes of two parallel-fed resonators, and then discharged using switches activated with rapidly fired plasma discharge tubes. Designs and high-power tests of several versions of the compressor are described. In these experiments, coherent pulse superposition was demonstrated at a 5–9 MW level of incident power. The compressed pulses observed had powers of 50–70 MW and durations of 40–70 ns. Peak power gains were measured to be in the range of 7:1–11:1 with efficiency in the range of 50–63%.

  10. TOF-SIMS study on surface modification of reed switch blades by pulsing nitrogen plasma

    NASA Astrophysics Data System (ADS)

    Arushanov, K. A.; Drozdov, M. N.; Karabanov, S. M.; Zeltser, I. A.; Tolstogouzov, A.

    2013-01-01

    A TOF.SIMS-5 by ION-TOF operating with pulsed 25 keV Bi+ for analysis and 2 keV Cs+ for sputtering was used to study depth compositional changes in near-surface layers of permalloy (iron-nickel) blades after treatment by pulsed nitrogen plasma directly in sealed reed switches. The formation of 350 nm-thick oxy-nitride coating in the contacting region of the blades was observed. It was found that the origin of this coating cannot be explained just by nitrogen and oxygen diffusion inside the treated material. Rather, cathode sputtering and re-deposition of sputtered products, thermal decomposition of nitrides and oxides along with sputter-induced surface roughening can also contribute in the formation of the modified layers.

  11. Multichannel microwave interferometer with an antenna switching system for electron density measurement in a laboratory plasma experiment

    SciTech Connect

    Kawamori, Eiichirou; Lin, Yu-Hsiang; Mase, Atsushi; Nishida, Yasushi; Cheng, C. Z.

    2014-02-15

    This study presents a simple and powerful technique for multichannel measurements of the density profile in laboratory plasmas by microwave interferometry. This technique uses electromechanical microwave switches to temporally switch the connection between multiple receiver antennas and one phase-detection circuit. Using this method, the phase information detected at different positions is rearranged into a time series that can be acquired from a minimum number of data acquisition channels (e.g., two channels in the case of quadrature detection). Our successfully developed multichannel microwave interferometer that uses the antenna switching method was applied to measure the radial electron density profiles in a magnetized plasma experiment. The advantage of the proposed method is its compactness and scalability to multidimensional measurement systems at low cost.

  12. Theoretical Modeling of the Plasma Erosion Opening Switch for Inductive Storage Applications.

    DTIC Science & Technology

    1983-10-27

    instantaneous and depends on the switch and load characteristics. In general T is finite and T >T >0. Thus energy will be lost to switch heatings s op - as...Top, then the switch opening time is the dominant factor and T T Clearly T must be small compared with the decay time of the load S op 5 current, T_

  13. Single-pulse driven, large-aperture 2×1 array plasma-electrodes optical switch for SG-II upgrading facility

    NASA Astrophysics Data System (ADS)

    Zhang, Jun; Wu, Dengsheng; Zheng, Jiangang; Zheng, Kuixing; Zhu, Qihua; Zhang, Xiongjun

    2014-12-01

    We demonstrate the design and performance of an optical switch that has been constructed for the SG-II upgrading facility. The device is a longitudinal, potassium di-hydrogen phosphate (KDP), 360 mm×360 mm aperture, and 2×1 array electro-optical switch driven by a 20 kV output switching-voltage pulse generator through two plasma electrodes produced at the rise edge of the switching-voltage pulse. The results show that the temporal responses and the spatial performance of the optical switch fulfill the operation requirements of the SG-II upgrading facility.

  14. Magnetohydrodynamic Simulation of the Chordal Wire-Array Plasma Flow Switch

    NASA Astrophysics Data System (ADS)

    Domonkos, Matthew; Amdahl, David

    2015-11-01

    The coaxial plasma flow switch (PFS) using a chordal wire array armature was first studied experimentally and computationally in the 1980's. That work revealed significant current interruption (dI/dt ~ 5 MA/ μs) as well as continuum x-ray emission representative of 30-45 keV bremsstrahlung. The work concluded that the voltage spike associated with the current interruption accelerated highly magnetized ions downstream at high velocity, and that energy exchange between the ions and electrons and their subsequent acceleration at the downstream boundary of the apparatus were responsible for the x-ray production. This work revisits the PFS operation up to and just beyond the point of armature lift-off from the coaxial section, where the magnetohydrodynamic model is valid and relevant. The early-time energy deposition in the wires from the pulse discharge is modeled in high-resolution 1-D and is used to set the initial conditions for the full-scale 3-D calculation. The wire array is assumed to have expanded from the initial r =0.01 cm uniformly and only in the axial direction, while the areal mass density retains its intended variation with radius. 3-D calculations are used to examine the armature, including magnetic field diffusion, as it is propelled along the coaxial geometry. These calculations will be used to set the initial conditions for follow-on particle or particle-fluid hybrid calculations of the propagation of ions and electrons to downstream obstacles and to calculate the x-ray production from the interactions of the flowing plasma with the obstacles.

  15. Ultrafast all-optical switching based on indium gallium arsenic phosphide grown by helium plasma-assisted molecular beam epitaxy

    NASA Astrophysics Data System (ADS)

    Qian, Li

    We present the first experimental study of the optical properties of HELP InGaAsP (InGaAsP grown by He-plasma- assisted molecular beam epitaxy) relevant to all-optical switching, and the first demonstration of picosecond switching using this material. We observed an optical response time of 15 ps, a nonlinear index change as large as 0.077, a sharp absorption band edge, and a small absorption tail in HELP InGaAsP. The unique coexistence of ultrafast response, large interband nonlinearity, and small band-tail absorption, never before reported, makes HELP InGaAsP particularly suitable for ultrafast all-optical switching. Additionally, faster response (subpicosecond) was achieved by doping the material with beryllium, and moderate doping (up to ~1018 cm-3) did not significantly alter the absorption edge. We systematically studied the response time variations with doping concentration, annealing temperature, carrier density, and wavelength. We conclude that, (a)Be doping reduces the response time by compensating for donor-like mid-gap states, thus increasing the electron trap concentration; (b)annealing removes defects responsible for fast carrier trapping; (c)the response time increases with carrier density due to limited trap states; (d)the response time varies with wavelength due to difference in electron and hole trapping cross-sections, which were determined based on experimental results and a phenomenological two-trap- level rate equation model. We investigated two types of HELP-InGaAsP-based all- optical switching devices, the nonlinear directional coupler (NLDC) and the asymmetric Fabry-Pérot (AFP) switch. Based on numerical modelling and waveguide loss measurements, we conclude that, while HELP-InGaAsP-based passive NLDCs are in principle viable, practical devices will tend to require high switching energy, and will likely experience low contrast and high insertion loss. We demonstrated that AFP devices will outperform NLDCs in contrast ratio, throughput

  16. Plasma-Opening-Switch-Driven Z-Pinch Experiments on Hawk

    NASA Astrophysics Data System (ADS)

    Commisso, R. J.; Apruzese, J. P.; Mosher, D.; Peterson, G. G.; Stephanakis, S. J.; Thornhill, J. W.; Young, F. C.; Weber, B. V.

    1996-11-01

    We present results from Ne, annular-gas-puff, z-pinch implosions driven by 0.5-MA currents on Hawk, an inductive-store pulsed-power generator with a plasma opening switch (POS). Several current monitors measure the pinch current and losses between the POS and the pinch. X-ray diagnostics include filtered vacuum diodes, a PCD, an x-ray spectrograph, and an x-ray pinhole-camera. The nearly constant driving current associated with the inductive Hawk generator (compared with finite width current pulses of conventional capacitive generators) allows investigation of implosions with different initial radii at approximately constant kinetic energy per unit mass. Results from such studies to determine the pinch quality as a function of initial radius for different gas nozzle designs will be discussed. The coupling between the POS and z-pinch is investigated by varying their axial separation. These results will also be discussed. This work is supported by DSWA. ^ NRC-NRL Research Associate.

  17. A Temporal Switch in the Germinal Center Determines Differential Output of Memory B and Plasma Cells

    PubMed Central

    Weisel, Florian J; Zuccarino-Catania, Griselda; Chikina, Maria

    2016-01-01

    Summary There is little insight into or agreement about the signals that control differentiation of memory B cells (MBC) and long-lived plasma cells (LLPC). By performing BrdU pulse-labeling studies, we found that MBC formation preceded the formation of LLPC in an adoptive transfer immunization system, which allowed for a synchronized Ag-specific response with homogeneous Ag-receptor, yet at natural precursor frequencies. We confirmed observations in wild type (WT) mice and extended them with germinal center (GC) disruption experiments and variable region gene sequencing. We thus show that the GC response undergo a temporal switch in its output as it matures, revealing that the reaction engenders both MBC subsets with different immune effector function and, ultimately, LLPC at largely separate points in time. These data demonstrate the kinetics of the formation of the cells that provide stable humoral immunity and therefore have implications for autoimmunity, vaccine development, and for understanding long-term pathogen resistance. PMID:26795247

  18. HPLC determination of cis-diamminedichloroplatinum(II) in plasma and urine with UV detection and column-switching.

    PubMed

    Kizu, R; Hayakawa, K; Miyazaki, M

    1989-01-01

    A method for determining cis-diamminedichloroplatinum(II) (CDDP), an anticancer drug, in plasma and urine by HPLC with UV detection and column-switching has been developed. Typical conditions were as follows. An apparatus was composed of two columns, two pumps, a UV detector, a sample injector with a 100 microL loop, a switching valve, a column oven and a recorder. A Rheodyne model 7125 sample injector was used as the switching valve. A precolumn (4.6 mm ID x 25 cm) was packed with MCI GEL CK10S (a strong cation exchanger), and an analytical column (4.6 mm ID x 5 cm) was packed with MCI GEL CDR10 (a strong anion exchanger). Both columns were connected in series via the switching valve. The CDDP-containing fraction of the effluent from the precolumn was loaded to the analytical column by column-switching and the effluent from the analytical column was monitored at 210 nm. An eluent of 0.3 M sodium dihydrogen phosphate was pumped at a flow rate of 1 mL/min and the columns were maintained at 40 degrees C. CDDP was eluted at about 11 min and the identity of the peak of CDDP on the chromatogram was confirmed by its 3-dimensional chromatogram and analysis of platinum in the column effluent. Under the conditions described above, a linear relationship was obtained between peak height and concentration of CDDP up to 100 microM. Correlation efficients were 0.998 for plasma and 0.999 for urine. The detection limit was 0.1 microM for CDDP in both plasma and urine (S/N = 3,0.005 AUFS). The reproducibility was within 3% for 10 determinations.(ABSTRACT TRUNCATED AT 250 WORDS)

  19. APPLICATIONS OF LASERS AND OTHER TOPICS IN LASER PHYSICS AND TECHNOLOGY: Switching of a pulsed ionic diode through the bulk of an ion source with laser plasma initiation

    NASA Astrophysics Data System (ADS)

    Pleshakova, R. P.; Shikanov, A. E.

    1987-10-01

    An analysis was made of the results of an investigation of switching of a pulsed ionic diode through the bulk of an ion source with a laser plasma and a vacuum arc. The dependences of the neutron yield on the electrical energy of the diode were recorded and analyzed. The results indicated a possible way of simple construction of an acceleration tube with switching via a laser-plasma source.

  20. Improvement of Plasma Biomarkers after Switching Stroke Patients from Other Angiotensin II Type I Receptor Blockers to Olmesartan.

    PubMed

    Tada, Yoshiteru; Yagi, Kenji; Uno, Masaaki; Matsushita, Nobuhisa; Kanematsu, Yasuhisa; Kuwayama, Kazuyuki; Shimada, Kenji; Nishi, Kyoko; Hirasawa, Motohiro; Satomi, Junichiro; Kitazato, Keiko T; Kageji, Teruyoshi; Matsuura, Eiji; Nagahiro, Shinji

    2015-07-01

    Managing hypertension is crucial for preventing stroke recurrence. Some stroke patients experience resistant hypertension. In our experimental stroke model, olmesartan increased the expression of angiotensin (Ang) II converting enzyme-2. We hypothesized that switching to olmesartan affects biomarkers and the blood pressure (BP) in stroke patients whose BP is insufficiently controlled by standard doses of Ang II type I receptor blockers (ARBs) other than olmesartan. We recruited 25 patients to study our hypothesis. All had a history of stroke or silent cerebral infarction. We switched them to olmesartan (10-40 mg per day) for 12 weeks and determined their plasma level of Ang-(1-7), peroxiredoxin, oxidized low-density lipoprotein (oxLDL)/β-2-glycoprotein I (β2GPI) complex, adiponectin, high mobility group box 1 (HMGB1), and tumor necrosis factor-α (TNFα) and recorded their BP before and after olmesartan treatment. After switching the patients to olmesartan, their plasma level of Ang-(1-7) as a vasoprotective indicator and adiponectin regulating metabolic syndrome was increased, and peroxiredoxin and the oxLDL/β2GPI complex indicating its antioxidative stress and its proatherogenicity were lower than their baseline. This suggests that olmesartan may be more effective than other ARBs to improve these conditions. Neither HMGB1 nor TNFα reflecting an inflammatory response was affected, suggesting that the anti-inflammatory effects of olmesartan are similar to those of other ARBs. The recommended BP (<140/90) was obtained in 10 of the 25 patients after switching to olmesartan. No adverse events occurred. Switching from other ARBs to olmesartan may be a promising therapeutic option in patients with resistant hypertension. Copyright © 2015 National Stroke Association. Published by Elsevier Inc. All rights reserved.

  1. Column-switching high-performance liquid chromatographic assay for determination of asiaticoside in rat plasma and bile with ultraviolet absorbance detection.

    PubMed

    Baek, M; Rho, Y S; Kim, D H

    1999-09-24

    A column-switching high-performance liquid chromatography (HPLC) method is described for the determination of asiaticoside in rat plasma and bile using column-switching and ultraviolet (UV) absorbance detection. Plasma was simply deproteinated with acetonitrile prior to injection and bile was directly injected onto the HPLC system consisting of a clean-up column, a concentrating column, and an analytical column, which were connected with two six-port switching valves. Detection of asiaticoside was accurate and repeatable, with a limit of quantification of 0.125 microg/ml in plasma and 1 microg/ml in bile. The calibration curves were linear in a concentration range of 0.125-2.5 microg/ml and 1-20 microg/ml for asiaticoside in rat plasma and bile, respectively. This method has been successfully applied to determine the level of asiaticoside in rat plasma and bile samples from pharmacokinetics and biliary excretion studies.

  2. A novel low-jitter plasma-jet triggered gas switch operated at a low working coefficient.

    PubMed

    Tie, Weihao; Liu, Shanhong; Liu, Xuandong; Zhang, Qiaogen; Pang, Lei; Liu, Longchen

    2014-02-01

    In this paper, we described the fabrication and testing of a novel plasma-jet triggered gas switch (PJTGS) operated at extremely low working coefficients with excellent triggered jitters. While the structure of the PJTGS is similar to that of a traditional three-electrode field-distortion gas switch, to improve its triggered performance we used a conical micro-plasma-gun with a needle-to-plate spark gap embedded in the trigger electrode. Applying a nanosecond pulse to the trigger electrode caused a spark discharge in the micro-plasma-gun. The electric field drove the discharge plasma to spray into the spark gap of the gas switch, causing fast breakdown. We tested the PJTGS with charging voltages of ±25 kV and a trigger voltage of +80 kV (5 ns rise time and 80 ns full width at half maximum) in two working modes. The PJTGS operated in Mode II had a lower triggered jitter and could be operated over a wider range of working coefficients than in Mode I under the same conditions. At working coefficients higher than 70%, we obtained sub-ns triggered jitters (<0.89 ns) from the PJTGS, at working coefficients lower than 50%, we obtained triggered jitters of 1.6-3.5 ns without no-fires or pre-fires. Even at a working coefficient of 27.4%, the PJTGS could still be triggered reliably with a delay time of 96.1 ns and a triggered jitter of 3.5 ns, respectively.

  3. A novel low-jitter plasma-jet triggered gas switch operated at a low working coefficient

    NASA Astrophysics Data System (ADS)

    Tie, Weihao; Liu, Shanhong; Liu, Xuandong; Zhang, Qiaogen; Pang, Lei; Liu, Longchen

    2014-02-01

    In this paper, we described the fabrication and testing of a novel plasma-jet triggered gas switch (PJTGS) operated at extremely low working coefficients with excellent triggered jitters. While the structure of the PJTGS is similar to that of a traditional three-electrode field-distortion gas switch, to improve its triggered performance we used a conical micro-plasma-gun with a needle-to-plate spark gap embedded in the trigger electrode. Applying a nanosecond pulse to the trigger electrode caused a spark discharge in the micro-plasma-gun. The electric field drove the discharge plasma to spray into the spark gap of the gas switch, causing fast breakdown. We tested the PJTGS with charging voltages of ±25 kV and a trigger voltage of +80 kV (5 ns rise time and 80 ns full width at half maximum) in two working modes. The PJTGS operated in Mode II had a lower triggered jitter and could be operated over a wider range of working coefficients than in Mode I under the same conditions. At working coefficients higher than 70%, we obtained sub-ns triggered jitters (<0.89 ns) from the PJTGS, at working coefficients lower than 50%, we obtained triggered jitters of 1.6-3.5 ns without no-fires or pre-fires. Even at a working coefficient of 27.4%, the PJTGS could still be triggered reliably with a delay time of 96.1 ns and a triggered jitter of 3.5 ns, respectively.

  4. Initial design and results from an ion current collection diagnostic for the triggered plasma opening switch experiment.

    SciTech Connect

    Jackson, Daniel Peter Jr.; Seidel, David Bruce; Gilmore, Mark; Mendel, Clifford Will, Jr.

    2005-06-01

    Study of the triggered plasma opening switch (TPOS) characteristics is in progress via an ion current collection diagnostic (ICCD), in addition to offline apparatus. This initial ion current collection diagnostic has been designed, fabricated, and tested on the TPOS in order to explore the opening profile of the main switch. The initial ion current collection device utilizes five collectors which are positioned perpendicularly to the main switch stage in order to collect radially traveling ions. It has been shown through analytical prowess that this specific geometry can be treated as a planar case of the Child-Langmuir law with only a 6% deviation from the cylindrical case. Additionally, magnetostatic simulations with self consistent space charge emitting surfaces of the main switch using the Trak code are under way. It is hoped that the simulations will provide evidence in support of both the analytical derivations and experimental data. Finally, an improved design of the ICCD (containing 12 collectors in the axial direction) is presently being implemented.

  5. Radiation hard vacuum switch

    DOEpatents

    Boettcher, Gordon E.

    1990-03-06

    A vacuum switch with an isolated trigger probe which is not directly connected to the switching electrodes. The vacuum switch within the plasmatron is triggered by plasma expansion initiated by the trigger probe which travels through an opening to reach the vacuum switch elements. The plasma arc created is directed by the opening to the space between the anode and cathode of the vacuum switch to cause conduction.

  6. Radiation hard vacuum switch

    DOEpatents

    Boettcher, Gordon E.

    1990-01-01

    A vacuum switch with an isolated trigger probe which is not directly connected to the switching electrodes. The vacuum switch within the plasmatron is triggered by plasma expansion initiated by the trigger probe which travels through an opening to reach the vacuum switch elements. The plasma arc created is directed by the opening to the space between the anode and cathode of the vacuum switch to cause conduction.

  7. Physical processes and modeling of plasma deposition and hardening of coatings-switched electrical parameters

    NASA Astrophysics Data System (ADS)

    Kadyrmetov, A. M.; Sharifullin, S. N.

    2016-11-01

    This paper presents the results of simulation of plasma deposition and hardening of coatings in modulating the electrical parameters. Mathematical models are based on physical models of gas-dynamic mechanisms more dynamic and thermal processes of the plasma jet. As an example the modeling of dynamic processes of heterogeneous plasma jet, modulated current pulses indirect arc plasma torch.

  8. Bipolar resistive switching characteristics of low temperature grown ZnO thin films by plasma-enhanced atomic layer deposition

    SciTech Connect

    Zhang Jian; Yang Hui; Zhang Qilong; Dong Shurong; Luo, J. K.

    2013-01-07

    ZnO films deposited by plasma-enhanced atomic layer deposition (PEALD) have been used to investigate resistive memory behavior. The bipolar resistance switching properties were observed in the Al/PEALD-ZnO/Pt devices. The resistance ratio for the high and low resistance states (HRS/LRS) is more than 10{sup 3}, better than ZnO devices deposited by other methods. The dominant conduction mechanisms of HRS and LRS are trap-controlled space charge limited current and Ohmic behavior, respectively. The resistive switching behavior is induced upon the formation/disruption of conducting filaments. This study demonstrated that the PEALD-ZnO films have better properties for the application in 3D resistance random access memory.

  9. Discharge dynamics and plasma density recovery by on/off switches of additional gas

    SciTech Connect

    Lee, Hyo-Chang; Kwon, Deuk-Chul; Oh, SeungJu; Kang, Hyun-Ju; Kim, Yu-Sin; Chung, Chin-Wook

    2016-06-15

    Measurement of the plasma density is investigated to study plasma dynamics by adding reactive gas (O{sub 2}) or rare gas (He) in Ar plasmas. When the O{sub 2} or He gas is added, plasma density is suddenly decreased, while the plasma density recovers slowly with gas off. It is found that the recovery time is strongly dependent on the gas flow rate, and it can be explained by effect of gas residence time. When the He gas is off in the Ar plasma, the plasma density is overshot compared to the case of the O{sub 2} gas pulsing due to enhanced ionizations by metastable atoms. Analysis and calculation for correlation between the plasma density dynamics and the gas pulsing are also presented in detail.

  10. Numerical simulations of output pulse extraction from a high-power microwave compressor with a plasma switch

    SciTech Connect

    Shlapakovski, Anatoli; Beilin, Leonid; Bliokh, Yuri; Donskoy, Moshe; Krasik, Yakov E.; Hadas, Yoav; Schamiloglu, Edl

    2014-05-07

    Numerical simulations of the process of electromagnetic energy release from a high-power microwave pulse compressor comprising a gas-filled cavity and interference switch were carried out. A microwave plasma discharge in a rectangular waveguide H-plane tee was modeled with the use of the fully electromagnetic particle-in-cell code MAGIC. The gas ionization, plasma evolution, and interaction with RF fields accumulated within the compressor were simulated using different approaches provided by the MAGIC code: particle-in-cell approach accounting for electron-neutral collisions, gas conductivity model based on the concept of mobility, and hybrid modeling. The dependences of the microwave output pulse peak power and waveform on parameters that can be controlled in experiments, such as an external ionization rate, RF field amplitude, and background gas pressure, were investigated.

  11. Improved operation of a microwave pulse compressor with a laser-triggered high-pressure gas plasma switch

    SciTech Connect

    Shlapakovski, A.; Gorev, S.; Krasik, Ya. E.

    2016-08-15

    The influence of laser beam parameters on the output pulses of a resonant microwave compressor with a laser-triggered plasma switch was investigated. The S-band compressor, consisting of a rectangular waveguide-based cavity and H-plane waveguide tee with a shorted side arm, was filled with pressurized dry air and pumped by 1.8-μs-long microwave pulses of up to 450 kW power. A Nd:YAG laser was used to ignite the gas discharge in the tee side arm for output pulse extraction. The laser beam (at 213 nm or 532 nm) was directed along the RF electric field lines. It was found that the compressor operated most effectively when the laser beam was focused at the center of the switch waveguide cross-section. In this case, the power extraction efficiency reached ∼47% at an output power of ∼14 MW, while when the laser beam was not focused the maximal extraction efficiency was only ∼20% at ∼6 MW output power. Focusing the laser beam resulted also in a dramatic decrease (down to <1 ns) in the delay of the output pulses' appearance with respect to the time of the beam's entrance into the switch, and the jitter of the output pulses' appearance was minimized. In addition, the quality of the output pulses' waveform was significantly improved.

  12. Improved operation of a microwave pulse compressor with a laser-triggered high-pressure gas plasma switch

    NASA Astrophysics Data System (ADS)

    Shlapakovski, A.; Gorev, S.; Krasik, Ya. E.

    2016-08-01

    The influence of laser beam parameters on the output pulses of a resonant microwave compressor with a laser-triggered plasma switch was investigated. The S-band compressor, consisting of a rectangular waveguide-based cavity and H-plane waveguide tee with a shorted side arm, was filled with pressurized dry air and pumped by 1.8-μs-long microwave pulses of up to 450 kW power. A Nd:YAG laser was used to ignite the gas discharge in the tee side arm for output pulse extraction. The laser beam (at 213 nm or 532 nm) was directed along the RF electric field lines. It was found that the compressor operated most effectively when the laser beam was focused at the center of the switch waveguide cross-section. In this case, the power extraction efficiency reached ˜47% at an output power of ˜14 MW, while when the laser beam was not focused the maximal extraction efficiency was only ˜20% at ˜6 MW output power. Focusing the laser beam resulted also in a dramatic decrease (down to <1 ns) in the delay of the output pulses' appearance with respect to the time of the beam's entrance into the switch, and the jitter of the output pulses' appearance was minimized. In addition, the quality of the output pulses' waveform was significantly improved.

  13. Hall-MHD and PIC Modeling of the Conduction-to-Opening Transition in a Plasma Opening Switch

    NASA Astrophysics Data System (ADS)

    Schumer, J. W.; SwanekampDdagger, S. B.; Ottinger, P. F.; Commisso, R. J.; Weber, B. V.

    1998-11-01

    Utilizing the fast opening characteristics of a plasma opening switch (POS), inductive energy storage devices can generate short-duration high-power pulses (<0.1 μ s, >1 TW) with current rise-times on the order of 10 ns. Plasma redistribution and thinning during the POS conduction phase can be modeled adequately with MHD methods. By including the Hall term in Ohm's Law, MHD methods can simulate plasmas with density gradient scale lengths between c/ω_pe < Ln < c/ω_pi. However, the neglect of electron inertia (c/ω_pe) and space-charge separation (λ_De) by single-fluid theory eventually becomes invalid in small gap regions that form during POS opening. PIC methods are well-suited for low-density plasmas, but are numerically taxed by high-density POS regions. An interface converts MHD (Mach2) output into PIC (Magic) input suitable for validating various transition criteria through comparison of current and density distributions from both methods. We will discuss recent progress in interfacing Hall-MHD and PIC simulations. Work supported by Defense Special Weapons Agency. ^ NRL-NRC Research Associate. hspace0.25in ^ JAYCOR, Vienna, VA 22102.

  14. Simultaneous determination of triple therapy for Helicobacter pylori in human plasma by reversed phase chromatography with online wavelength switching

    NASA Astrophysics Data System (ADS)

    Ahmed, Sameh; Atia, Noha N.

    2015-02-01

    The infection of gastric mucosa by Helicobacter pylori (HP) is an essential cofactor in the aetiology of gastroduodenal ulcer and gastric carcinoma. Because of the bacterial resistance, combination therapy containing omeprazole (OME), tinidazole (TNZ) and clarithromycin (CLA) is commonly used for eradication of HP. However, the simultaneous determination of the triple therapy in human plasma was not reported. A simple, reproducible, and selective HPLC method was developed for the simultaneous determination of the triple therapy mixture used for management of HP infections in human plasma. An HPLC procedure based on a liquid-liquid extraction, enrichment of the analytes and subsequent reversed-phase chromatography with UV detection was used. To enable sensitive and selective detection, the method involved the use of online wavelength switching detection, with two different detection wavelengths; 280 nm for detection of OME and TNZ and 210 nm for detection of CLA. Separations were performed on C18 analytical column with acetonitrile-10 mM phosphate buffer of pH = 3.0 at flow rate of 1.0 mL min-1. The linear ranges in human plasma were 0.05-10 μg mL-1 with correlation coefficients >0.9990. The detection limits in human plasma were 0.02-0.07 μg mL-1. Validation parameters were assessed in compliance with US-FDA guidelines. The method proved to be valuable for the therapeutic drug monitoring after oral administration of triple therapy tablets.

  15. Experimental Results from SHIVA Star Vacuum Inductive Store/Plasma Flow Switch Driven Implosions

    DTIC Science & Technology

    1987-06-01

    energy density plasmas and intense radiation pulses1• In 1976-1978, we achieved direct capacitor drive, 1.0 to 1.5 ~s implosions of aluminum and...early 1970’s, the Air Force Weapons Laboratory has been investigating the electromagnetic implosion of cylindrical plasma liners to produce high

  16. An overview of Sandia National Laboratories` plasma switched, gigawatt, ultra-wideband impulse transmitter program

    SciTech Connect

    Clark, R.S.; Rinehart, L.F.; Buttram, M.T.; Aurand, J.F.

    1992-11-01

    Sandia National Laboratories has developed several repetitive, ultra-wideband (UWB), impulse transmitters to address impulse source technology and to support experimental applications. The sources fall into two different classes, pulse peaking and pulse shorting depending on how the UWB frequency components are generated. ne frequency spectrum of the radiated pulse from these sources include the spectrum of 100-MHz to 3-GHz. Depending upon the source, repetitive operation from single shot to 5-kHz (1-kHz nominal) has been obtained with excellent reliability and repeatability. SNIPER (Sub-Nanosecond impulse Radiator) is a source which uses an oil peaking switch to obtain a fast risetime (250-pS) pulse of 2-nS duration. The output voltage ranges between few tens of kilovolts to 250-kV. EMBL (EnantioMorphic Blumlein) is a similar device (presently under development) which uses a gas switch to sharpen the trailing edge of a 2-nS pulse to approximately 100-pS. To date, an output voltage of approximately 600-kV has been obtained (700- kV is the design goal). Since the frequency spectra are identical between sources with sharpened leading or trailing edges, alternatively, one can use parallel switches to short the pulse at its peak voltage. The pulse is generated externally and then injected into the antenna. Due to the high powers involved and the need to radiate a broad spectrum of frequencies, Sandia has concentrated on TEM horn. antennas with special high voltage feed adapters. Several TEM horns have been built and used during this program. In those cases where higher gains are desired for the higher frequencies, TEM horn-fed, dish antennas have been employed. An overview of the UWB transmitters, including design and operation of the modulators, the PFN`S, the pulse sharpening switches and the antennas will be presented.

  17. An overview of Sandia National Laboratories' plasma switched, gigawatt, ultra-wideband impulse transmitter program

    SciTech Connect

    Clark, R.S.; Rinehart, L.F.; Buttram, M.T.; Aurand, J.F.

    1992-01-01

    Sandia National Laboratories has developed several repetitive, ultra-wideband (UWB), impulse transmitters to address impulse source technology and to support experimental applications. The sources fall into two different classes, pulse peaking and pulse shorting depending on how the UWB frequency components are generated. ne frequency spectrum of the radiated pulse from these sources include the spectrum of 100-MHz to 3-GHz. Depending upon the source, repetitive operation from single shot to 5-kHz (1-kHz nominal) has been obtained with excellent reliability and repeatability. SNIPER (Sub-Nanosecond impulse Radiator) is a source which uses an oil peaking switch to obtain a fast risetime (250-pS) pulse of 2-nS duration. The output voltage ranges between few tens of kilovolts to 250-kV. EMBL (EnantioMorphic Blumlein) is a similar device (presently under development) which uses a gas switch to sharpen the trailing edge of a 2-nS pulse to approximately 100-pS. To date, an output voltage of approximately 600-kV has been obtained (700- kV is the design goal). Since the frequency spectra are identical between sources with sharpened leading or trailing edges, alternatively, one can use parallel switches to short the pulse at its peak voltage. The pulse is generated externally and then injected into the antenna. Due to the high powers involved and the need to radiate a broad spectrum of frequencies, Sandia has concentrated on TEM horn. antennas with special high voltage feed adapters. Several TEM horns have been built and used during this program. In those cases where higher gains are desired for the higher frequencies, TEM horn-fed, dish antennas have been employed. An overview of the UWB transmitters, including design and operation of the modulators, the PFN'S, the pulse sharpening switches and the antennas will be presented.

  18. An overview of Sandia National Laboratories' plasma switched, gigawatt, ultra-wideband impulse transmitter program

    NASA Astrophysics Data System (ADS)

    Clark, R. S.; Rinehart, L. F.; Buttram, M. T.; Aurand, J. F.

    Sandia National Laboratories has developed several repetitive, ultra-wideband (UWB), impulse transmitters to address impulse source technology and to support experimental applications. The sources fall into two different classes, pulse peaking and pulse shorting depending on how the UWB frequency components are generated. The frequency spectrum of the radiated pulse from these sources include the spectrum of 100-MHz to 3-GHz. Depending upon the source, repetitive operation from single shot to 5-kHz (1-kHz nominal) has been obtained with excellent reliability and repeatability. SNIPER (Sub-Nanosecond Impulse Radiator) is a source which uses an oil peaking switch to obtain a fast risetime (250-pS) pulse of 2-nS duration. The output voltage ranges between few tens of kilovolts to 250-kV. EMBL (EnantioMorphic Blumlein) is a similar device (presently under development) which uses a gas switch to sharpen the trailing edge of a 2-nS pulse to approximately 100-pS. To date, an output voltage of approximately 600-kV has been obtained (700-kV is the design goal). Since the frequency spectra are identical between sources with sharpened leading or trailing edges, alternatively, one can use parallel switches to short the pulse at its peak voltage. The pulse is generated externally and then injected into the antenna. Due to the high powers involved and the need to radiate a broad spectrum of frequencies, Sandia has concentrated on TEM horn antennas with special high voltage feed adapters. Several TEM horns have been built and used during this program. In those cases where higher gains are desired for the higher frequencies, TEM horn-fed, dish antennas have been employed. An overview of the UWB transmitters, including design and operation of the modulators, the PFN'S, the pulse sharpening switches and the antennas will be presented.

  19. Synchronizable Q-switched, mode-locked, and cavity-dumped ruby laser for plasma diagnostics

    NASA Astrophysics Data System (ADS)

    Houtman, H.; Meyer, J.

    1985-06-01

    We report on the design and operation of an optimized version of a Q-switched, mode-locked, and cavity-dumped ruby-laser oscillator. The modulator window is much narrower than that assumed in conventional active mode-lock theory, and is shown to yield much shorter pulses than the latter in cases where the number of round trips is restricted. To allow a high-power pulse (≊1 GW) to evolve in the oscillator, and to allow simple synchronization to a (˜100 ns fixed delay) CO2 laser, a limit of 23 round trips was chosen, but similar limits may be imposed by lasers having short-gain duration as in an excimer laser. Details are given on the single spark gap switching element and Pockels cells, with an analysis of their expected switching speeds, in order to establish the effectiveness of the modulator, as compared to conventional sinusoidally driven active mode lockers. Single pulses of 50-70 mJ are reliably cavity-dumped after only 100-ns delay (23 round trips) with pulse length adjustable from 50-100 ps with ±5-ps stability. Relative timing between the main (CO2) and probe (ruby) pulses allows a measurement accuracy of ±50 ps to be attained.

  20. Fluoxetine and norfluoxetine analysis by direct injection of human plasma in a column switching liquid chromatographic system.

    PubMed

    Santos-Neto, Alvaro J; Fernandes, Christian; Rodrigues, José C; Alves, Claudete; Lanças, Fernando M

    2008-01-01

    A column switching LC method is presented for the analysis of fluoxetine (FLU) and norfluoxetine (NFLU) by direct injection of human plasma using a lab-made restricted access media (RAM) column. A RAM-BSA-octadecyl silica (C-18) column (40 mm x 4.6 mm, 10 microm) is evaluated in both backflush and foreflush elution modes and coupled with a C-18 lab-made (50 mm x 4.6 mm, 3 microm) analytical column in order to perform online sample preparation. Direct injection of 100 microL of plasma samples is possible with the developed approach. In addition, reduction of sample handling is obtained when compared with traditional liquid-liquid extraction (LLE) and SPE. The total analysis time is around 20 min. A LOQ of 15 ng/mL is achieved in a concentration range of 15-500 ng/mL, allowing the therapeutic drug monitoring of clinical samples. The precision values achieved are lower than 15% for all the evaluated points with adequate recovery and accuracy. Furthermore, no matrix interferences are found in the analysis and the proposed method shows to be an adequate alternative for analysis of FLU in plasma.

  1. Resistance Switching Characteristics Induced by O2 Plasma Treatment of an Indium Tin Oxide Film for Use as an Insulator in Resistive Random Access Memory.

    PubMed

    Chen, Po-Hsun; Chang, Ting-Chang; Chang, Kuan-Chang; Tsai, Tsung-Ming; Pan, Chih-Hung; Chen, Min-Chen; Su, Yu-Ting; Lin, Chih-Yang; Tseng, Yi-Ting; Huang, Hui-Chun; Wu, Huaqiang; Deng, Ning; Qian, He; Sze, Simon M

    2017-01-25

    In this study, an O2 inductively coupled plasma (ICP) treatment was developed in order to modify the characteristics of indium tin oxide (ITO) film for use as an insulator in resistive random access memory (RRAM). After the O2 plasma treatment, the previously conductive ITO film is oxidized and becomes less conductive. In addition, after capping the same ITO material for use as a top electrode, we found that the ITO/ITO(O2 plasma)/TiN device exhibits very stable and robust resistive switching characteristics. On the contrary, the nontreated ITO film for use as an insulator in the ITO/ITO/TiN device cannot perform resistance switching behaviors. The material analysis initially investigated the ITO film characteristics with and without O2 plasma treatment. The surface was less rough after O2 plasma treatment. However, the molar concentration of each element and measured sheet resistance results for the O2-plasma-treated ITO film were dramatically modified. Next, electrical measurements were carried out to examine the resistance switching stability under continuous DC and AC operation in this ITO/ITO(O2 plasma)/TiN device. Reliability tests, including endurance and retention, also proved its capability for use in data storage applications. In addition to these electrical measurements, current fitting method experiments at different temperatures were performed to examine and confirm the resistance switching mechanisms. This easily fabricated device, using a simple material combination, achieves excellent performance by using ITO with an O2 plasma treatment and can further the abilities of RRAM for use in remarkable potential applications.

  2. Rapid and direct analysis of statins in human plasma by column-switching liquid chromatography with restricted-access material.

    PubMed

    Fagundes, Vinicius Freire; Leite, Camila Prado; Pianetti, Gerson Antonio; Fernandes, Christian

    2014-02-01

    This study presents the development of a column-switching liquid chromatographic method with direct injection of human plasma for simultaneous determination of four statins (lovastatin, pravastatin, rosuvastatin and simvastatin), the main class of drugs used in the treatment of hyperlipidemia. By using a C18 (30 mm × 4.6 mm, 15 μm) a lab made bovine serum albumin restricted access material (RAM) column was prepared and compared with a commercial alquil-diol silica RAM column (C18, 25 mm × 4.0 mm, 25 μm) in terms of their protein exclusion capacity and micromolecules retention. Foreflush and backflush modes were compared for both RAM columns to the number of theoretical plates, asymmetry, resolution and chromatographic run time. The developed method was validated in the range from 125 to 876 ng mL(-1) for lovastatin, rosuvastatin and simvastatin, and from 500 to 2000 ng mL(-1) for pravastatin, presenting selectivity, precision and accuracy intra and inter-run. Total analysis time (sample preparation and chromatographic separation) was only 16 min when the backflush mode was employed in the column-switching system.

  3. Bone Marrow Mesenchymal Stem Cells Enhance the Differentiation of Human Switched Memory B Lymphocytes into Plasma Cells in Serum-Free Medium

    PubMed Central

    Gervais-St-Amour, Catherine

    2016-01-01

    The differentiation of human B lymphocytes into plasma cells is one of the most stirring questions with regard to adaptive immunity. However, the terminal differentiation and survival of plasma cells are still topics with much to be discovered, especially when targeting switched memory B lymphocytes. Plasma cells can migrate to the bone marrow in response to a CXCL12 gradient and survive for several years while secreting antibodies. In this study, we aimed to get closer to niches favoring plasma cell survival. We tested low oxygen concentrations and coculture with mesenchymal stem cells (MSC) from human bone marrow. Besides, all cultures were performed using an animal protein-free medium. Overall, our model enables the generation of high proportions of CD38+CD138+CD31+ plasma cells (≥50%) when CD40-activated switched memory B lymphocytes were cultured in direct contact with mesenchymal stem cells. In these cultures, the secretion of CXCL12 and TGF-β, usually found in the bone marrow, was linked to the presence of MSC. The level of oxygen appeared less impactful than the contact with MSC. This study shows for the first time that expanded switched memory B lymphocytes can be differentiated into plasma cells using exclusively a serum-free medium. PMID:27872867

  4. Laser-triggered high-voltage plasma switching with diffractive optics.

    PubMed

    Ekberg, M; Sunesson, A; Bergkvist, M; Gustavsson, A; Isberg, J; Bernhoff, H; Skytt, P; Bengtsson, J; Hård, S; Larsson, M

    2001-06-01

    High-power lasers can be used to induce ionization of gases and thereby enable rapid triggering of electrical discharge devices, potentially faster than any devices based on mechanical or solid-state switching. With diffractive optical elements (DOEs) the laser light can conveniently be directed to positions within the gas so that an electrical discharge between two high-voltage electrodes is triggered reliably and rapidly. Here we report on two different types of DOE used for creating an electrical discharge in pure argon for potential high-voltage applications. One is the diffractive equivalent of a conventional axicon that yields an extended, and continuous, high-intensity focal region between the electrodes. The other is a multiple-focal-distance kinoform--a DOE that is designed to produce a linear array of 20 discrete foci, with high peak intensities, between the electrodes. We show that DOEs enable efficient, rapid switching and may provide increased flexibility in the design of novel electrode configurations.

  5. Determination of taspoglutide in human and animal plasma using liquid chromatography-tandem mass spectrometry with orthogonal column-switching.

    PubMed

    Heinig, Katja; Wirz, Thomas

    2009-05-15

    A highly sensitive liquid chromatographic method with online solid-phase extraction (SPE) and tandem mass spectrometric detection was developed for the quantification of the synthetic peptide drug taspoglutide in human and animal plasma. Sample preparation consisted of simple protein precipitation or automated off-line SPE using mixed mode cation exchange material, optionally preceded by cleavage of potential antidrug antibody complexes. Excellent selectivity was obtained by a novel orthogonal column switching approach, employing hydrophilic interaction liquid chromatography (HILIC) for online SPE followed by chromatographic separation on a 300 A pore size C18 column. The use of a stable isotope labeled drug (C-terminal arginine containing six (13)C and four (15)N atoms) as internal standard improved the quality and ruggedness of the method. The lower limits of quantitation (LLOQ) in human and animal plasma were 10.0 and 50.0 pg/mL, respectively, extracting only 250 or 100 microL sample aliquots. Precisions and accuracies were below 15% CV and between 89% and 114%, respectively. The method was successfully employed to analyze samples from pharmacokinetic studies.

  6. Determination of the polar drug dimiracetam in human plasma and serum by column-switching high-performance liquid chromatography.

    PubMed

    Torchio, L; Lombardi, F; Visconti, M; Doyle, E

    1995-04-07

    A sensitive and fully automated column-switching HPLC method was developed for the determination of a novel cognition enhancer, dimiracetam, in human plasma and serum. A sample of plasma was ultrafiltered and then directly injected onto a first mu Bondapak C18 column. The sample was eluted with water. The portion of the eluate (heart-cut) from this column containing the drug was selected and loaded on a second mu Bondapak C18 column and eluted with water. During the elution of the second column, the first column was automatically rinsed with water-acetonitrile (50:50, v/v) and then equilibrated for a new injection. The total analysis time for each sample was 35 min. This corresponded to a 30% decrease in analysis time compared with the time that would have been needed with a simple run with two mu Bondapak C18 columns assembled in series. Ultraviolet detection at 200 nm was used to monitor the eluate. The method was fully validated over the quantitation range 27 ng/ml-15 micrograms/ml. The applicability of the method was demonstrated by analysis of serum samples from a study performed in human healthy volunteers.

  7. A radiation hard vacuum switch

    DOEpatents

    Boettcher, G.E.

    1988-07-19

    A vacuum switch with an isolated trigger probe which is not directly connected to the switching electrodes. The vacuum switch within the plasmatron is triggered by plasma expansion initiated by the trigger probe which travels through an opening to reach the vacuum switch elements. The plasma arc created is directed by the opening to the space between the anode and cathode of the vacuum switch to cause conduction. 3 figs.

  8. Plasma membranes as heat stress sensors: from lipid-controlled molecular switches to therapeutic applications.

    PubMed

    Török, Zsolt; Crul, Tim; Maresca, Bruno; Schütz, Gerhard J; Viana, Felix; Dindia, Laura; Piotto, Stefano; Brameshuber, Mario; Balogh, Gábor; Péter, Mária; Porta, Amalia; Trapani, Alfonso; Gombos, Imre; Glatz, Attila; Gungor, Burcin; Peksel, Begüm; Vigh, László; Csoboz, Bálint; Horváth, Ibolya; Vijayan, Mathilakath M; Hooper, Phillip L; Harwood, John L; Vigh, László

    2014-06-01

    The classic heat shock (stress) response (HSR) was originally attributed to protein denaturation. However, heat shock protein (Hsp) induction occurs in many circumstances where no protein denaturation is observed. Recently considerable evidence has been accumulated to the favor of the "Membrane Sensor Hypothesis" which predicts that the level of Hsps can be changed as a result of alterations to the plasma membrane. This is especially pertinent to mild heat shock, such as occurs in fever. In this condition the sensitivity of many transient receptor potential (TRP) channels is particularly notable. Small temperature stresses can modulate TRP gating significantly and this is influenced by lipids. In addition, stress hormones often modify plasma membrane structure and function and thus initiate a cascade of events, which may affect HSR. The major transactivator heat shock factor-1 integrates the signals originating from the plasma membrane and orchestrates the expression of individual heat shock genes. We describe how these observations can be tested at the molecular level, for example, with the use of membrane perturbers and through computational calculations. An important fact which now starts to be addressed is that membranes are not homogeneous nor do all cells react identically. Lipidomics and cell profiling are beginning to address the above two points. Finally, we observe that a deregulated HSR is found in a large number of important diseases where more detailed knowledge of the molecular mechanisms involved may offer timely opportunities for clinical interventions and new, innovative drug treatments. This article is part of a Special Issue entitled: Membrane Structure and Function: Relevance in the Cell's Physiology, Pathology and Therapy. Copyright © 2013 The Authors. Published by Elsevier B.V. All rights reserved.

  9. Vacuum Inductive Store/Pulse Compression Experiments on a High Power Accelerator Using Plasma Opening Switches.

    DTIC Science & Technology

    1983-03-31

    1975). 12. G. Cooperstein, J.J. Condon, and J.R. Boller, J. Vac. Sci. Technol. 10, 961 (1973). 13. C. W. Mendel, Jr., D. M. Zagar , G. S . Mills, S ...REPORT NUNSER 7. AUTNOR11(4j S . CONTRACT ORt GRANT NU-MERt.) R. A. Meger,* R. J1. Commusso,* G. Cooperstein, and Shyke A. Goldstein* 9. PERFORMING...1982 IEEE International Conf. on Plasma Sci., Ottawa, Canada, IEEE cat. no. 82-CH-1770-7 (1982), p. 154. 7. C. W. Mendel, Jr. and S . A. Goldstein, J

  10. Experimental studies of a microsecond plasma opening switch in the positive polarity regime with inductive load/extraction ion diode

    NASA Astrophysics Data System (ADS)

    Bystritskii, V. M.; Lisitsyn, I. V.; Sinebryukhov, V. A.; Volkov, S. N.; Krasik, Ya. E.

    1992-06-01

    Systematic studies of the microsecond plasma opening switch (MPOS) operation in the positive polarity of its inner electrode with an inductive load/B-applied ion diode of the extraction type at a level of 0.3 TW of dissipated power were performed at the DOUBLE generator (300 kA, 480 kV, 1 μs). The detailed measurements of ion flow parameters in the conductive phase of the MPOS showed the considerable enhancement of the ion current amplitude over the thermal flow limit (3-10 times) which is coupled with a significant decrease of electron conductivity in the MPOS across its self-magnetic field. The positive polarity MPOS operation proved to be more critical to the stored current amplitudes and geometry of the electrodes in comparison with the negative polarity case. This fact resulted in limitations of satisfactory performance of the MPOS involving short high-voltage pulse duration, low stored current amplitudes, and a narrow region of acceptable electrode diameters. The variation of the diode anode-cathode (AC) gap provided a sensitive control of the MPOS + magnetically insulated diode (MID) system, which displayed very strong coupling, resulting in clamping of the output voltage in a wide region of diode impedances. The early long-duration (<300 ns) high-voltage (50-200 kV) prepulse improves plasma production at the anode of the MID prior to the application of the main pulse. The optimal performance of the MPOS+MID system was realized at the level of ZMPOS/ZMID = 2.5. The energy of the extracted high-power ion beam made up 3.5 kJ, its power being 120 GW with 40% efficiency of energy transfer from MPOS to the MID.

  11. Ion-pair chromatography of methotrexate in a column-switching system using an alkyl-diol silica precolumn for direct injection of plasma.

    PubMed

    Yu, Z; Westerlund, D

    1996-08-23

    The retention behaviour of methotrexate as an ion-pair with tetrabutylammonium in a column-switching system, based on an alkyl-diol silica C8 precolumn, combined with an analytical column, LiChrospher RP 18, was studied. Methotrexate is mainly present as a divalent anion at pH 7.4, however, the retention data was consistent with the formation of a 1 + 1 ion pair with the counter ion. The concentration of the tetrabutylammonium and the acetonitrile in the mobile phase could be used to regulate the retention in the system. Relevant chromatographic parameters to estimate the enrichment effect in the column-switching system are also identified and discussed. The column-switching system was applied to direct injection of plasma (100 microliters) giving a limit of detection of 10 ng/ml for methotrexate using UV detection at 307 nm.

  12. 5.8kV SiC PiN Diode for Switching of High-Efficiency Inductive Pulsed Plasma Thruster Circuits

    NASA Technical Reports Server (NTRS)

    Toftul, Alexandra; Polzin, Kurt A.; Hudgins, Jerry L.

    2014-01-01

    Inductive Pulsed Plasma Thruster (IPPT) pulse circuits, such as those needed to operate the Pulsed Inductive Thruster (PIT), are required to quickly switch capacitor banks operating at a period of µs while conducting current at levels on the order of at least 10 kA. [1,2] For all iterations of the PIT to date, spark gaps have been used to discharge the capacitor bank through an inductive coil. Recent availability of fast, high-power solid state switching devices makes it possible to consider the use of semiconductor switches in modern IPPTs. In addition, novel pre-ionization schemes have led to a reduction in discharge energy per pulse for electric thrusters of this type, relaxing the switching requirements for these thrusters. [3,4] Solid state switches offer the advantage of greater controllability and reliability, as well as decreased drive circuit dimensions and mass relative to spark gap switches. The use of solid state devices such as Integrated Gate Bipolar Transistors (IGBTs), Gate Turn-off Thyristors (GTOs) and Silicon-Controlled Rectifiers (SCRs) often involves the use of power diodes. These semiconductor devices may be connected antiparallel to the switch for protection from reverse current, or used to reduce power loss in a circuit by clamping off current ringing. In each case, higher circuit efficiency may be achieved by using a diode that is able to transition, or 'switch,' from the forward conducting state ('on' state) to the reverse blocking state ('off' state) in the shortest amount of time, thereby minimizing current ringing and switching losses. Silicon Carbide (SiC) PiN diodes offer significant advantages to conventional fast-switching Silicon (Si) diodes for high power and fast switching applications. A wider band gap results in a breakdown voltage 10 times that of Si, so that a SiC device may have a thinner drift region for a given blocking voltage. [5] This leads to smaller, lighter devices for high voltage applications, as well as reduced

  13. A column switching ultrahigh-performance liquid chromatography-tandem mass spectrometry method to determine anandamide and 2-arachidonoylglycerol in plasma samples.

    PubMed

    Marchioni, Camila; de Souza, Israel Donizeti; Grecco, Caroline Fernandes; Crippa, José Alexandre; Tumas, Vitor; Queiroz, Maria Eugênia Costa

    2017-03-23

    This study reports a fast, sensitive, and selective column switching ultrahigh-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method to determine the endocannabinoids (eCBs), anandamide (AEA), and 2-arachidonoylglycerol (2-AG) in plasma samples. This bidimensional system used a restricted access media column (RP-8 ADS, 25 mm × 4 mm × 25 μM) in the first dimension and a core-shell Kinetex C18 (100 mm × 2, 1.7 mm × 1 μM) column in the second dimension, followed by detection in a mass spectrometer triple quadrupole (multiple reactions monitoring mode) operating in the positive mode. RP-8 ADS was used for trace enrichment of eCBs (reverse phase partitioning) and macromolecular matrix size exclusion; the core-shell column was used for the chromatographic separation. The column switching UHPLC-MS/MS method presented a linear range spanning from 0.1 ng mL(-1) (LOQ) to 6 ng mL(-1) for AEA and from 0.04 ng mL(-1) (LOQ) to 10 ng mL(-1) for 2-AG. Excluding the LLOQ values, the precision assays provided coefficients of variation lower than 8% and accuracy with relative standard error values lower than 14%. Neither carryover nor matrix effects were detected. This high-throughput column switching method compared to conventional methods is time saving as it involves fewer steps, consumes less solvent, and presents lower LLOQ. The column switching UHPLC-MS/MS method was successfully applied to determine AEA and 2-AG in plasma samples obtained from Alzheimer's disease patients. Graphical abstract A column switching ultra high-performance liquid chromatography-tandem mass spectrometry method using RP-8 ADS column and core shell column to determine endocannabinoids in plasma samples.

  14. In Situ Control of Oxygen Vacancies in TaOx Thin Films via Plasma-Enhanced Atomic Layer Deposition for Resistive Switching Memory Applications.

    PubMed

    Egorov, Konstantin V; Kuzmichev, Dmitry S; Chizhov, Pavel S; Lebedinskii, Yuri Yu; Hwang, Cheol Seong; Markeev, Andrey M

    2017-04-06

    The plasma-enhanced atomic layer deposition (PEALD) process using Ta(OC2H5)5 as a Ta precursor and plasma-activated hydrogen as a reactant for the deposition of TaOx films with a controllable concentration of oxygen vacancies (VO) is reported herein. The VO concentration control was achieved by varying the hydrogen volume fraction of the hydrogen-argon mixture in the plasma, allowing the control of the leakage current density in the tantalum oxide films within the range of 5 orders of magnitude compared with the Ta2O5 film grown via thermal ALD using the identical Ta precursor and H2O. Temperature-dependent current-voltage measurements combined with Poole-Frenkel emission modeling demonstrated that the bulk trap depth decreases with the increasing hydrogen volume fraction, which could be attributed to the increase of the VO concentration. The possible chemical change in the PEALD TaOx films grown under different hydrogen volume fractions was confirmed by the in situ X-ray photoelectron spectroscopy (XPS) measurements of the Ta 4f core and valence band spectra. The comparison of the XPS-measured nonstoichiometry and the secondary ion mass spectrometry analysis of the hydrogen content allowed this study to conclude that the nonstoichiometry is largely related to the formation of Ta-VO sites rather than of Ta-H sites. Such oxygen-deficient TaOx layers were studied for application as an oxygen-deficient layer in a resistance switching random access memory stack (Ta2O5/TaOx) where the actual switching occurred within the stoichiometric Ta2O5 layer. The bilayer memory stack showed reliable resistance switching up to ∼10(6) switching cycles, whereas the single-layer Ta2O5 memory showed only several hundred switching cycles.

  15. Plasma switch as a temporal overlap tool for pump-probe experiments at FEL facilities

    NASA Astrophysics Data System (ADS)

    Harmand, M.; Murphy, C. D.; Brown, C. R. D.; Cammarata, M.; Döppner, T.; Düsterer, S.; Fritz, D.; Förster, E.; Galtier, E.; Gaudin, J.; Glenzer, S. H.; Göde, S.; Gregori, G.; Hilbert, V.; Hochhaus, D.; Laarmann, T.; Lee, H. J.; Lemke, H.; Meiwes-Broer, K.-H.; Moinard, A.; Neumayer, P.; Przystawik, A.; Redlin, H.; Schulz, M.; Skruszewicz, S.; Tavella, F.; Tschentscher, T.; White, T.; Zastrau, U.; Toleikis, S.

    2012-08-01

    We have developed an easy-to-use and reliable timing tool to determine the arrival time of an optical laser and a free electron laser (FEL) pulses within the jitter limitation. This timing tool can be used from XUV to X-rays and exploits high FELs intensities. It uses a shadowgraph technique where we optically (at 800 nm) image a plasma created by an intense XUV or X-ray FEL pulse on a transparent sample (glass slide) directly placed at the pump - probe sample position. It is based on the physical principle that the optical properties of the material are drastically changed when its free electron density reaches the critical density. At this point the excited glass sample becomes opaque to the optical laser pulse. The ultra-short and intense XUV or X-ray FEL pulse ensures that a critical electron density can be reached via photoionization and subsequent collisional ionization within the XUV or X-ray FEL pulse duration or even faster. This technique allows to determine the relative arrival time between the optical laser and the FEL pulses in only few single shots with an accuracy mainly limited by the optical laser pulse duration and the jitter between the FEL and the optical laser. Considering the major interest in pump-probe experiments at FEL facilities in general, such a femtosecond resolution timing tool is of utmost importance.

  16. Influence of focal point properties on energy transfer and plasma evolution during laser ignition process with a passively q-switched laser.

    PubMed

    Bärwinkel, Mark; Lorenz, Sebastian; Stäglich, Robert; Brüggemann, Dieter

    2016-07-11

    Miniaturized passively q-switched laser ignition systems are a promising alternative to conventional ignition sources to ensure a reliable ignition under difficult conditions. In this study the influences of focal point properties on energy transfer from laser to plasma as well as plasma formation and propagation are investigated as the first steps of the laser induced ignition process. Maximum fluence and fluence volume are introduced to characterize focal point properties for varying laser pulse energies and focusing configurations. The results show that the transferred laser energy increases with increasing maximum fluence. During laser emission plasma propagates along the beam path of the focused laser beam. Rising maximum fluence results in increased plasma volume, but expansion saturates when fluence volume reaches its maximum.

  17. Determination of indinavir in human cerebrospinal fluid and plasma by solid-phase extraction and high-performance liquid chromatography with column switching.

    PubMed

    Zhong, L; Yeh, K C

    1999-10-29

    A rapid, sensitive and robust sample preparation procedure for the quantitative determination of indinavir in human cerebrospinal fluid (CSF) and plasma is described. Indinavir and the internal standard were isolated from CSF or plasma samples by cation-exchange solid-phase extraction with SCX cartridges, while the chromatographic separation was adopted from a previous method, using a cyano column connected by a switching valve to a C18 column. UV detection was set at 210 nm. The standard curve was linear over the concentration range of 2 to 2000 ng/ml in CSF and 5 to 2000 ng/ml in plasma. The intra-day coefficients of variation at all concentration levels were < or = 5.9%. The inter-day consistency was assessed by running QC samples during each daily run. The coefficients of variation for quality control samples in both matrixes were < or = 6.1%. The method has been utilized to support clinical pharmacokinetic studies.

  18. Narrowbore high-performance liquid chromatography for the simultaneous determination of sildenafil and its metabolite UK-103,320 in human plasma using column switching.

    PubMed

    Jeong, C K; Lee, H Y; Jang, M S; Kim, W B; Lee, H S

    2001-03-05

    A fully automated narrowbore high-performance liquid chromatography method with column switching was developed for the simultaneous determination of sildenafil and its active metabolite UK-103,320 in human plasma samples without pre-purification. Diluted plasma sample (100 microl) was directly introduced onto a Capcell Pak MF Ph-1 column (20x4 mm I.D.) where primary separation occurred to remove proteins and concentrate target substances using 15% acetonitrile in 20 mM phosphate solution (pH 7). The drug molecules eluted from the MF Ph-1 column were focused in an intermediate column (35x2 mm I.D.) by a valve switching step. The substances enriched in the intermediate column were eluted and separated on a phenyl-hexyl column (100x2 mm I.D.) using 36% acetonitrile in 10 mM phosphate solution (pH 4.5) when the valve status was switched back. The method showed excellent sensitivity (detection limit of 10 ng/ml), good precision (RSD < or = 2.3%) and accuracy (bias: +/-2.0%) and speed (total analysis time 17 min). The response was linear (r2 > or = 0.999) over the concentration range 10-1000 ng/ml.

  19. Design and Operation of a Two-Color Interferometer to Measure Plasma and Neutral Gas Densities in a Laser-Triggered Spark Gap Switch

    NASA Astrophysics Data System (ADS)

    Camacho, J. F.; Ruden, E. L.; Domonkos, M. T.; Schmitt-Sody, A.; Lucero, A.

    2014-10-01

    A Mach-Zehnder imaging interferometer, operating with 1064-nm and 532-nm wavelength beams from a short-pulse laser and a frequency-doubled branch, respectively, has been designed and built to simultaneously measure plasma free electron and neutral gas densities profiles within a laser-triggered spark gap switch with a 5-mm gap. The switch will be triggered by focusing a separate 532-nm or 1064-nm laser pulse along the gap's axis to trigger low-jitter breakdown. Illuminating the gap transverse to this axis, the diagnostic will generate interferograms for each wavelength, which will then be numerically converted to phase-shift maps. These will be used to calculate independent line-integrated free electron and neutral density profiles by exploiting their different frequency dispersion curves. The density profiles themselves, then, will be calculated by Abel inversion. Details of the interferometer's design will be presented along with density data obtained using a variety of fill gasses at various pressures. Other switch parameters will be varied as well in order to characterize more fully the performance of the switch.

  20. Application of an alkyl-diol silica precolumn in a column-switching system for the determination of meloxicam in plasma.

    PubMed

    Baeyens, W R G; Van der Weken, G; D'haeninck, E; García-Campaña, A M; Vankeirsbilck, T; Vercauteren, A; Deprez, P

    2003-08-08

    The group of LiChrospher alkyl-diol silica (ADS) phases that make part of the unique family of restricted-access materials, have been developed as special packings used in the liquid chromatographic integrated sample processing of biofluids. The advantage of these phases lies in the possibility of direct injection of untreated plasma. An on-line elimination of the protein matrix is achieved with a quantitative recovery together with an on-column enrichment. The present method describes a hand-operated on-line switching high-performance liquid chromatographic system for the determination of meloxicam. Spiked plasma samples were introduced on the ADS precolumn using a 0.05 M phosphate buffer, pH 6.0. After washing with the buffer the ADS column was backflushed with the mobile phase 0.05 M phosphate buffer-30% (v/v) acetonitrile (ACN)-25 mM t-butylamine (TBA) at a pH of 7.0, thus transferring the analyte to the analytical column LiChrocart 125-4 LiChrospher RP-8. The eluent was monitored by a UV-detector set at 364 nm. The developed column-switching method is fully applicable to plasma injections.

  1. Analysis of drugs in plasma samples from schizophrenic patients by column-switching liquid chromatography-tandem mass spectrometry with organic-inorganic hybrid cyanopropyl monolithic column.

    PubMed

    Domingues, Diego Soares; Souza, Israel Donizeti de; Queiroz, Maria Eugênia Costa

    2015-07-01

    This study reports on the development of a rapid, selective, and sensitive column-switching liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to analyze sixteen drugs (antidepressants, anticonvulsants, anxiolytics, and antipsychotics) in plasma samples from schizophrenic patients. The developed organic-inorganic hybrid monolithic column with cyanopropyl groups was used for the first dimension of the column-switching arrangement. This arrangement enabled online pre-concentration of the drugs (monolithic column) and their subsequent analytical separation on an XSelect SCH C18 column. The drugs were detected on a triple quadrupole tandem mass spectrometer (multiple reactions monitoring mode) with an electrospray ionization source in the positive ion mode. The developed method afforded adequate linearity for the sixteen target drugs; the coefficients of determination (R(2)) lay above 0.9932, the interassay precision had coefficients of variation lower than 6.5%, and the relative standard error values of the accuracy ranged from -14.0 to 11.8%. The lower limits of quantification in plasma samples ranged from 63 to 1250pgmL(-1). The developed method successfully analyzed the target drugs in plasma samples from schizophrenic patients for therapeutic drug monitoring (TDM).

  2. Effect of switching to risperidone after unsuccessful treatment with aripiprazole on plasma monoamine metabolites level in the treatment of acute schizophrenia.

    PubMed

    Miura, Itaru; Takeuchi, Satoshi; Katsumi, Akihiko; Kanno, Keiko; Watanabe, Kenya; Mashiko, Hirobumi; Niwa, Shin-Ichi

    2012-09-01

    In the treatment of acute schizophrenia, risperidone and aripiprazole are both placed the first line antipsychotics. These two antipsychotics have different pharmacological effects. We investigated the effects of risperidone on plasma levels of homovanillic acid (HVA) and 3-methoxy-4hydroxyphenylglycol after unsuccessful aripiprazole treatment in acute schizophrenia. Ten Japanese patients with acute schizophrenia were enrolled to this study. Plasma levels of monoamine metabolites were analyzed with high-performance liquid chromatography with electrochemical detection. Risperidone improved the symptoms and 4 of 10 patients were responders. Risperidone showed a tendency to decrease plasma HVA (pHVA) levels in responders (p = 0.068), but not in non-responders (p = 1.0). At baseline, pHVA levels of responders were significantly higher than that of non-responders (p = 0.033). A trend for negative correlation was found between pHVA at baseline and the changes in Positive and Negative Syndrome Scale-Total (p = 0.061, r = -0.61). Our results suggest that high pHVA level before switching may predict good response to the second line antipsychotics after unsuccessful first antipsychotic treatment. If aripiprazole is not effective in acute schizophrenia, switching to risperidone may be effective and reasonable strategy for improving symptoms. Copyright © 2012 John Wiley & Sons, Ltd.

  3. Damage threshold and focusability of mid-infrared free-electron laser pulses gated by a plasma mirror with nanosecond switching pulses

    SciTech Connect

    Wang, Xiaolong; Nakajima, Takashi; Zen, Heishun; Kii, Toshiteru; Ohgaki, Hideaki

    2013-11-04

    The presence of a pulse train structure of an oscillator-type free-electron laser (FEL) results in the immediate damage of a solid target upon focusing. We demonstrate that the laser-induced damage threshold can be significantly improved by gating the mid-infrared FEL pulses with a plasma mirror. Although the switching pulses we employ have a nanosecond duration which does not guarantee the clean wavefront of the gated FEL pulses, the high focusability is experimentally confirmed through the observation of spectral broadening by a factor of 2.1 when we tightly focus the gated FEL pulses onto the Ge plate.

  4. A pH Switch Regulates the Inverse Relationship between Membranolytic and Chaperone-like Activities of HSP-1/2, a Major Protein of Horse Seminal Plasma.

    PubMed

    Kumar, C Sudheer; Swamy, Musti J

    2016-07-05

    HSP-1/2, a major protein of horse seminal plasma binds to choline phospholipids present on the sperm plasma membrane and perturbs its structure by intercalating into the hydrophobic core, which results in an efflux of choline phospholipids and cholesterol, an important event in sperm capacitation. HSP-1/2 also exhibits chaperone-like activity (CLA) in vitro and protects target proteins against various kinds of stress. In the present study we show that HSP-1/2 exhibits destabilizing activity toward model supported and cell membranes. The membranolytic activity of HSP-1/2 is found to be pH dependent, with lytic activity being high at mildly acidic pH (6.0-6.5) and low at mildly basic pH (8.0-8.5). Interestingly, the CLA is also found to be pH dependent, with high activity at mildly basic pH and low activity at mildly acidic pH. Taken together the present studies demonstrate that the membranolytic and chaperone-like activities of HSP-1/2 have an inverse relationship and are regulated via a pH switch, which is reversible. The higher CLA observed at mildly basic pH could be correlated to an increase in surface hydrophobicity of the protein. To the best of our knowledge, this is the first study reporting regulation of two different activities of a chaperone protein by a pH switch.

  5. 6-7 Mev Characteristic Gamma-Ray Source Using A Plasma Opening Switch And A Marx Bank

    DTIC Science & Technology

    2011-06-01

    CH2) lined outer conductor surface bombarding the center conductor. The Figure 1. Thick target yield for the 19F(p,αγ)16O reaction on a PTFE...produced by various (p,n) and (d,n) reactions in the PTFE target. The source of the ions is either (or both) the injected plasma or the anode plasma...created on the electron-heated surface of the CH2. The plasma gun PTFE insulation is not the primary proton source. Impurities from residual water

  6. Results of Fiber-Optic-Interferometer Density Measurements Performed in the Plasma-Opening-Switch Region of DM1

    DTIC Science & Technology

    1999-06-01

    1015 cm-3 • The shot to shot variation in the cable gun plasma is measured to be about fu1 In - 10 to 20 %. When the Marx bank is fired, a burst of...in the cable gun plasma is measured to be about An I n - 10 to 20 %. When the Marx bank is fired, a burst of plasma is observed to travel axially...em Cathode :::::::= Marx Bank Diode Figure 2. Schematic ofPOS region ofDMl. II. EXPERIMENTAL RESULTS- MEASUREMENTS PERFORMED ON THE CABLE GUN

  7. Magnetoresistive waves in plasmas

    NASA Astrophysics Data System (ADS)

    Felber, F. S.; Hunter, R. O., Jr.; Pereira, N. R.; Tajima, T.

    1982-10-01

    The self-generated magnetic field of a current diffusing into a plasma between conductors can magnetically insulate the plasma. Propagation of magnetoresistive waves in plasmas is analyzed. Applications to plasma opening switches are discussed.

  8. Single-pulse picking at kHz repetition rates using a Ge plasma switch at the free-electron laser FELBE.

    PubMed

    Schmidt, J; Winnerl, S; Seidel, W; Bauer, C; Gensch, M; Schneider, H; Helm, M

    2015-06-01

    We demonstrate a system for picking of mid-infrared and terahertz (THz) radiation pulses from the free-electron laser (FEL) FELBE operating at a repetition rate of 13 MHz. Single pulses are reflected by a dense electron-hole plasma in a Ge slab that is photoexcited by amplified near-infrared (NIR) laser systems operating at repetition rates of 1 kHz and 100 kHz, respectively. The peak intensity of picked pulses is up to 400 times larger than the peak intensity of residual pulses. The required NIR fluence for picking pulses at wavelengths in the range from 5 μm to 30 μm is discussed. In addition, we show that the reflectivity of the plasma decays on a time scale from 100 ps to 1 ns dependent on the wavelengths of the FEL and the NIR laser. The plasma switch enables experiments with the FEL that require high peak power but lower average power. Furthermore, the system is well suited to investigate processes with decay times in the μs to ms regime, i.e., much longer than the 77 ns long pulse repetition period of FELBE.

  9. Single-pulse picking at kHz repetition rates using a Ge plasma switch at the free-electron laser FELBE

    SciTech Connect

    Schmidt, J. Helm, M.; Winnerl, S.; Seidel, W.; Schneider, H.; Bauer, C.; Gensch, M.

    2015-06-15

    We demonstrate a system for picking of mid-infrared and terahertz (THz) radiation pulses from the free-electron laser (FEL) FELBE operating at a repetition rate of 13 MHz. Single pulses are reflected by a dense electron-hole plasma in a Ge slab that is photoexcited by amplified near-infrared (NIR) laser systems operating at repetition rates of 1 kHz and 100 kHz, respectively. The peak intensity of picked pulses is up to 400 times larger than the peak intensity of residual pulses. The required NIR fluence for picking pulses at wavelengths in the range from 5 μm to 30 μm is discussed. In addition, we show that the reflectivity of the plasma decays on a time scale from 100 ps to 1 ns dependent on the wavelengths of the FEL and the NIR laser. The plasma switch enables experiments with the FEL that require high peak power but lower average power. Furthermore, the system is well suited to investigate processes with decay times in the μs to ms regime, i.e., much longer than the 77 ns long pulse repetition period of FELBE.

  10. Automated analysis of fluvoxamine in rat plasma using a column-switching system and ion-pair high-performance liquid chromatography.

    PubMed

    Liu, Shicheng; Shinkai, Norihiro; Kakubari, Ikuhiro; Saitoh, Hideo; Noguchi, Ken-ichi; Saitoh, Takashi; Yamauchi, Hitoshi

    2008-12-01

    We have established a robust, fully automated analytical method for the analysis of fluvoxamine in rat plasma using a column-switching ion-pair high-performance chromatography system. The plasma sample was injected onto a precolumn packed with Shim-pack MAYI-ODS (50 microm), where the drug was automatically purified and enriched by on-line solid-phase extraction. After elution of the plasma proteins, the analyte was back-flushed from the precolumn and then separated isocratically on a reversed-phase C18 column (L-column ODS) with a mobile phase (acetonitrile-0.1% phosphoric acid, 36:64, v/v) containing 2 mM sodium 1-octanesulfonate. The analyte was monitored by a UV detector at a wavelength of 254 nm. The calibration line for fluvoxamine showed good linearity in the range of 5-5000 ng/mL (r > 0.999) with the limit of quantification of 5 ng/mL (RSD = 6.51%). Accuracy ranged from -2.94 to 4.82%, and the within- and between-day precision of the assay was better than 8% across the calibration range. The analytical sensitivity and accuracy of this assay is suitable for characterization of the pharmacokinetics of orally-administered fluvoxamine in rats.

  11. Thermal/plasma-driven reversible wettability switching of a bare gold film on a poly(dimethylsiloxane) surface by electroless plating.

    PubMed

    Wu, Jian; Bai, Hai-Jing; Zhang, Xian-Bo; Xu, Jing-Juan; Chen, Hong-Yuan

    2010-01-19

    We report an approach for fabricating a tunable wettability surface by electroless gold plating on poly(dimethylsiloxane) (PDMS). A two-layer structured gold film with a tight layer and a loose layer can be obtained on the surface of a PDMS chip when the PDMS chip is immersed in a gold plating solution at 30 degrees C for 4 h. Its wettability can be rapidly switched between superhydrophilicity and superhydrophobicity by plasma and heat treatments without any self-assembled monolayer, and the superhydrophobicity can be even changed from the gecko-foot-hair-like character to the lotus-leaf-like character. Benefiting from the various wettabilities of the prepared gold/PDMS composites, protein patterning is successfully achieved on a patterned superhydrophobic/superhydrophilic gold/PDMS composite; a superhydrophobic needle for transferring supersmall water droplets (1 microL) to a superhydrophobic surface is successfully fabricated.

  12. Impact of Platelet-Rich Plasma on Bone Height Changes around Platform Switched Implants Supporting Mandibular Overdentures in Controlled Diabetic Patients

    PubMed Central

    Ibraheem, Eman Mostafa Ahmed; Eldeen, Amany Mohy

    2015-01-01

    BACKGROUND: The platform switching concept was recently introduced to implant dentistry involving the reduction of restoration abutment diameter with respect to the diameter of dental implant. Long-term follow-up around these implants showed higher levels of bone preservation and proper stress distribution and improved esthetics. AIM: The aim of the present study was to evaluate the changes in bone height by means of radiographic examination around platform switched implant supporting mandibular overdentures in controlled diabetic patients. SUBJECTS AND METHODS: Fourteen male complete edentulous patients were selected and enrolled in a follow-up study plan. Split mouth technique was applied; one side implant chosen randomly with Platelet-rich-plasma (PRP) and the other without PRP, bone height changes was assessed by Cone Beam Computed Tomography (CBCT) radiographic examination after 3 months, 6 months, 9 months and 1 year later. RESULTS: There was increase in bone height loss in both sides but with no statistical significance difference between the two sides after 3 months, 6 months, 9 months and 1 year respectively. CONCLUSION: The result of this article satisfied the patients both esthetically and functionally with recorded increase in bone height loss. PMID:27275316

  13. uv preilluminated gas switches

    SciTech Connect

    Bradley, L.P.; Orham, E.L.; Stowers, I.F.; Braucht, J.R.

    1980-06-03

    We have designed, built, and characterized uv preilluminated gas switches for a trigger circuit and a low inductance discharge circuit. These switches have been incorporated into a 54 x 76 x 150 cm pulser module to produce a 1 Ma output current rising at 5 x 10/sup 12/ amps/sec with 1 ns jitter. Twenty such modules will be used on the Nova Inertial Confinement Fusion Laser System for plasma retropulse shutters.

  14. Polarization switching in ferroelectric cathodes

    SciTech Connect

    Rosenman, G.; Shur, D.; Garb, K.; Cohen, R.; Krasik, Y.E.

    1997-07-01

    A new mechanism of polarization switching and electron emission in ferroelectric cathodes is proposed. Surface flashover plasma of a ferroelectric origin was observed on a polar ferroelectric surface [D. Shur, G. Rosenman, and Ya. E. Krasik, Appl. Phys. Lett. {bold 70}, 574 (1997)]. Simultaneous measurements of switched charge and plasma density show that expanding surface plasma represents a dynamic switching electrode. Direct measurements of ion/electron emission currents and surface analysis implemented by different analytic tools indicate that electrons and ions from the surface plasma contribute to spontaneous polarization screening. The high energy of charged particles emitted from the surface plasma is ascribed to a high surface potential during polarization switching. {copyright} {ital 1997 American Institute of Physics.}

  15. Application of the restricted-access precolumn packing material alkyl-diol silica in a column-switching system for the determination of ketoprofen enantiomers in horse plasma.

    PubMed

    Baeyens, W R; Van der Weken, G; Haustraete, J; Aboul-Enein, H Y; Corveleyn, S; Remon, J P; García-Campaña, A M; Deprez, P

    2000-02-25

    The group of LiChrospher ADS (alkyl-diol silica) sorbents that make part of a unique family of restricted-access materials, have been developed as special packings for precolumns used in the LC-integrated sample processing of biofluids. The advantage of these sorbents lies in the direct injection of untreated biological fluids, that is without sample clean-up, the elimination of the protein matrix with a quantitative recovery together with an on-column enrichment. The present method is based on previous work applying UV detection at 260 nm for ketoprofen determinations. Plasma samples introduced to the ADS precolumn using a 0.1 M phosphate buffer, pH 7.0. After washing with the buffer the ADS column was backflushed with the mobile phase 0.01 M phosphate buffer-6% (v/v) 2-propanol-5 mM octanoic acid at a pH of 5.5, thus transporting the analytes to the chiral-HSA (human serum albumin) (100x4.0 mm) column where the separation of the ketoprofen enantiomers was achieved with a resolution factor of 1.4. The developed column-switching method was fully applicable to plasma injections.

  16. A review of opening switch technology for inductive energy storage

    NASA Astrophysics Data System (ADS)

    Schoenbach, K. H.; Kristiansen, M.; Schaefer, G.

    1984-08-01

    A review of the state of the art in opening switches is presented. The general operating principles and present and potential future operating parameters for several switch categories are discussed. Among the switch categories described are: mechanical, solid state, vacuum arc, crossed field, fuse, explosive, plasma gun, superconducting, thermal, MHD instability, diffuse discharge, plasma erosion switches, and reflex triodes.

  17. Differential coulometric oxidation following post column-switching high pressure liquid chromatography for fluorescence measurement of unmetabolized folic acid in human plasma.

    PubMed

    Bailey, Steven W; Ayling, June E

    2013-11-08

    Although many countries have fortified their grain supplies with folic acid (FA) to decrease the incidence of neural tube defects, others have not due to concerns that this synthetic folate might have some adverse effects. Persistent unmetabolized FA has been found even in plasma from fasted subjects. To facilitate measurement of low levels of folic acid in human plasma, post-column coulometric oxidative cleavage was used to convert poorly fluorescent FA into a highly fluorescent compound determined to be 6-formyl-pterin. To minimize sample work-up and maximize recovery, column-switching HPLC transferred a window of eluate containing the FA from the first column (C8) onto a second column (phenyl-hexyl). The pH of two mobile phases were adjusted to be above and then below a pK of the FA α-carboxyl group, thus promoting separation from compounds coeluting from the C8-column. This permitted sample preparation using only a simple high recovery protein precipitation. Definitive identification of FA in human plasma was accomplished by duplicate injections of sample with the electrochemical voltage set above and below its half-potential. The LOD (S/N=3) was 0.10 nM. The intra- and inter-assay CV's were 2.3% and 5%, respectively. Comparison of these results with those obtained by HPLC/MS/MS with stable isotope internal standard showed a slope of 1.00 ± 0.019. This simple, sensitive, and repeatable assay facilitates a more thorough investigation of the response of various human populations to folic acid intake. Post-column differential coulometric electrochemistry can expand the variety of compounds amenable to fluorescence detection.

  18. Power flow between a plasma-opening switch and a load separated by a high-inductance magnetically insulated transmission line

    NASA Astrophysics Data System (ADS)

    Swanekamp, S. B.; Grossmann, J. M.; Ottinger, P. F.; Commisso, R. J.; Goyer, J. R.

    1994-09-01

    Results are presented from particle-in-cell simulations of the electron flow launched from a plasma opening switch (POS) into a magnetically insulated transmission line (MITL) as the POS opens. The opening process of the POS is treated by removing plasma from a fixed anode-cathode gap with an opening time of tau(sub rise). To be similar to opening switch experiments at Physics International, the simulations were performed with the same inductance L(sub MITL) between the POS and load. When L(sub MITL)/tau(sub rise) is large compared to the POS flow impedance, this inductance effectively isolates the POS from the load during the opening process and the POS voltage is insensitive to changes in the load impedance. Analysis and simulations show that the peak load power is maximized when the load impedance is equal to the POS flow impedance. In contrast to previous theories and simulations of magnetically insulated flows, a large amount of electron flow in the MITL is concentrated near the anode. This is a result of the high effective impedance imposed on the POS by the inductive load which causes a significant electron current loss in the POS. As a result, many electrons lose insulation on the load side of the POS gap and those that do flow into the MITL have been accelerated to nearly the full POS potential. Electrons then E cross B drift on equipotential lines close to the anode as they enter the MITL and flow toward the load. Current losses in the MITL are observed due to the proximity of the electron flow to the anode. Some electrons flow from the MITL directly into the load and are registered as load current while others E cross B drift back toward the POS along the cathode surface. This is possible because the electron flow launched into the MITL from the POS is large enough to cause sufficient positive image charges on the cathode so that the electric field points out of the cathode surface.

  19. Dust-acoustic solitary modes in plasmas with isothermal and nonthermal ions: Polarity switches and coexistence domains

    SciTech Connect

    Verheest, Frank

    2011-08-15

    Large dust-acoustic waves are investigated in a multispecies plasma model consisting of cold negative dust in the presence of cooler Boltzmann and hotter nonthermal Cairns positive ions, in a Sagdeev pseudopotential formalism. Use of the pseudopotential at the acoustic speed itself yields in a systematic way compositional parameter values where negative/positive solitons interchange polarities and also where both polarities coexist. The latter requires that solitons at the acoustic speed exist, with finite amplitudes, compared to superacoustic solitons of the opposite polarity. The coexistence region starts when the pseudopotential at the acoustic speed has a negative root at the limit of infinite dust compression and ends when a positive double root is encountered. Outside the coexistence domain, only negative or positive superacoustic solitons can exist. Thus, the discussion and numerical evaluations are guided by precise physical and analytic arguments rather than mere numerical experimentation. Graphs of relevant Sagdeev pseudopotentials illustrate the link with the analytical constraints.

  20. Exciter switch

    NASA Technical Reports Server (NTRS)

    Mcpeak, W. L.

    1975-01-01

    A new exciter switch assembly has been installed at the three DSN 64-m deep space stations. This assembly provides for switching Block III and Block IV exciters to either the high-power or 20-kW transmitters in either dual-carrier or single-carrier mode. In the dual-carrier mode, it provides for balancing the two drive signals from a single control panel located in the transmitter local control and remote control consoles. In addition to the improved switching capabilities, extensive monitoring of both the exciter switch assembly and Transmitter Subsystem is provided by the exciter switch monitor and display assemblies.

  1. Switch wear leveling

    DOEpatents

    Wu, Hunter; Sealy, Kylee; Gilchrist, Aaron

    2015-09-01

    An apparatus for switch wear leveling includes a switching module that controls switching for two or more pairs of switches in a switching power converter. The switching module controls switches based on a duty cycle control technique and closes and opens each switch in a switching sequence. The pairs of switches connect to a positive and negative terminal of a DC voltage source. For a first switching sequence a first switch of a pair of switches has a higher switching power loss than a second switch of the pair of switches. The apparatus includes a switch rotation module that changes the switching sequence of the two or more pairs of switches from the first switching sequence to a second switching sequence. The second switch of a pair of switches has a higher switching power loss than the first switch of the pair of switches during the second switching sequence.

  2. Determination of lansoprazole enantiomers in dog plasma by column-switching liquid chromatography with tandem mass spectrometry and its application to a preclinical pharmacokinetic study.

    PubMed

    Wang, Hao; Sun, Yantong; Meng, Xiangjun; Yang, Bo; Wang, Jian; Yang, Yan; Gu, Jingkai

    2015-09-01

    Lansoprazole, a selective proton pump inhibitor, has a chiral benzimidazole sulfoxide structure and is used for the treatment of gastric acid hypersecretory related diseases. To investigate its stereoselective pharmacokinetics, a column-switching liquid chromatography with tandem mass spectrometry method was developed for the determination of lansoprazole enantiomers in dog plasma using (+)-pantoprazole as an internal standard. After a simple protein precipitation procedure with acetonitrile, matrix components left behind after sample preparation were further eliminated from the sample by reversed-phase chromatography on a C18 column. The fluent was fed to a chiral column for the separation of lansoprazole enantiomers. Baseline separation of lansoprazole enantiomers was achieved on a Chiralcel OZ-RH column using acetonitrile/0.1% formic acid in water (35:65, v/v) as the mobile phase at 40°C. The linearity of the calibration curves ranged from 3 to 800 ng/mL for each enantiomer. Intra- and inter-day precisions ranged from 2.1 to 7.3% with an accuracy of ±1.7% for (+)-lansoprazole, and from 1.6 to 6.9% with an accuracy of ±3.5% for (-)-lansoprazole, respectively. The validated method was successfully applied for the stereoselective pharmacokinetic study of lansoprazole in beagle dog after intravenous infusion.

  3. Coaxial Switch

    DTIC Science & Technology

    2014-04-23

    08-2015 Publication Coaxial Switch David J. Bamford et al Naval Undersea Warfare Center Division, Newport 1176 Howell Street, Bldg 102T, Code 00L...Distribution A A coaxial switch having a housing and a shaft extending through and rotatably mounted to the housing. The shaft extends from opposite...conductor members are electrically connected together. When the coaxial switch is engaged, the conductor members are inserted into the connector body

  4. FAST ACTING CURRENT SWITCH

    DOEpatents

    Batzer, T.H.; Cummings, D.B.; Ryan, J.F.

    1962-05-22

    A high-current, fast-acting switch is designed for utilization as a crowbar switch in a high-current circuit such as used to generate the magnetic confinement field of a plasma-confining and heat device, e.g., Pyrotron. The device particularly comprises a cylindrical housing containing two stationary, cylindrical contacts between which a movable contact is bridged to close the switch. The movable contact is actuated by a differential-pressure, airdriven piston assembly also within the housing. To absorb the acceleration (and the shock imparted to the device by the rapidly driven, movable contact), an adjustable air buffer assembly is provided, integrally connected to the movable contact and piston assembly. Various safety locks and circuit-synchronizing means are also provided to permit proper cooperation of the invention and the high-current circuit in which it is installed. (AEC)

  5. Optical switches and switching methods

    DOEpatents

    Doty, Michael

    2008-03-04

    A device and method for collecting subject responses, particularly during magnetic imaging experiments and testing using a method such as functional MRI. The device comprises a non-metallic input device which is coupled via fiber optic cables to a computer or other data collection device. One or more optical switches transmit the subject's responses. The input device keeps the subject's fingers comfortably aligned with the switches by partially immobilizing the forearm, wrist, and/or hand of the subject. Also a robust nonmetallic switch, particularly for use with the input device and methods for optical switching.

  6. The Plasma Erosion Opening Switch.

    DTIC Science & Technology

    1985-05-14

    Boller, Bull. Am. Phys. Soc. 28, 1055 (1983). 20. C. W. Mendel, Jr., D. M. Zagar , G. S . Mills, S . Humphries, Jr. and S . A. Goldstein, Rev. Sci. Instrum...LABORATORY Lj-- Washington, D.C. Approved for public release; distribution unlimited. *85 5 13 .103 ;: P" R S fl C.7N *’w ’ S 𔃼C REPORT DOCUMENTATION PAGE E C...REPORT NJUMBER( S ) NRL IMemorandum Report 5560 6a NAME OF PERFORMING ORGANIZATION 6o OFrICE SYMBOL 7a NAME OF MONITORING ORGANIZATIONI (if applicable

  7. ION SWITCH

    DOEpatents

    Cook, B.

    1959-02-10

    An ion switch capable of transferring large magnitudes of power is described. An ion switch constructed in accordance with the invention includes a pair of spaced control electrodes disposed in a highly evacuated region for connection in a conventional circuit to control the passing of power therethrough. A controllable ionic conduction path is provided directiy between the control electrodes by a source unit to close the ion switch. Conventional power supply means are provided to trigger the source unit and control the magnitude, durations and pulse repetition rate of the aforementioned ionic conduction path.

  8. Magnetically insulated opening switch research

    NASA Astrophysics Data System (ADS)

    McGeoch, M. W.; Kraft, R.

    1987-01-01

    We examine the feasibility of an opening switch concept based on magnetic insulation in a coaxial thermionic diode. It is found that the impedance ratio between closed and open states of the diode is marginal for efficient energy transfer via this type of switch. The open, or insulated state of the diode is characterized by current leakage across the magnetic field which is associated with the presence of plasma waves.

  9. Effect of ASA dose doubling versus switching to clopidogrel on plasma inflammatory markers concentration in patients with type 2 diabetes and high platelet reactivity: the AVOCADO study.

    PubMed

    Rosiak, Marek; Postula, Marek; Kaplon-Cieslicka, Agnieszka; Kondracka, Agnieszka; Trzepla, Ewa; Czlonkowski, Andrzej; Janicki, Piotr K; Filipiak, Krzysztof J; Opolski, Grzegorz

    2013-01-01

    The aim of the study was to compare the effects of 2 strategies of antiplatelet treatment (i.e., 150 mg ASA vs. 75 mg clpoidogrel) on plasma level of inflammatory markers in type 2 diabetes mellitus (T2DM) patients with high platelet reactivity (HPR). Study cohort consisted of 304 T2DM patients on chronic ASA therapy (75 mg per day) participating in the Aspirin Versus/Or Clopidogrel in Aspirin-resistant Diabetics inflammation Outcomes (AVOCADO) study. Patients with HPR defined as Platelet Function Analyzer (PFA)-100 collagene/epinephrine closure time (CEPI-CT) < 193 s (n = 80) were randomized to 150 mg of ASA or 75 mg of clopidogrel in 2:3 ratio, respectively. Concentrations of the selected inflammatory markers, including tumor necrosis factor (TNF)-α, interleukin (IL)-6, solubleCD40 ligand (sCD40L), and high sensitivity C-reactive protein (hsCRP), were measured and compared in both treatment groups before and after 8 weeks of treatment in both groups. Out of 234 patients included into final analysis, the total of 34.2% (n = 80) patients displayed HPR, of which 14.1% (n = 33) were randomized into 150 mg of ASA group and 20.1% (n = 47) into 75 mg of clopidogrel group. Treatment with clopidogrel was a positive predictor (stepwise multiple regression analysis) of reduction of sCD40L concentration (odds ratio [OR] 4.15; p = 0.013), while treatment with 150 mg ASA was a positive predictor of reduction of IL-6 concentration (OR 4.38; p = 0.033). There was no statistically significant differences between clopidogrel and ASA 150 mg treatment in respect to predictive value for decreased hsCRP concentrations or increased TNF-α concentrations. Increasing the dose of ASA from 75 mg to 150 mg daily or switching ASA 75 mg to clopidogrel 75 mg daily may reduce concentrations of some inflammatory markers (in particular hsCRP, IL-6 and CD40L) in T2DM patients with HPR treated previously with 75 mg of ASA.

  10. Arterial switch.

    PubMed

    Planche, C; Lacour-Gayet, F; Serraf, A

    1998-01-01

    A relatively large spectra of anatomic variations are found within the unifying features of discordant ventriculoarterial connections. Variants that lend themselves to anatomic repair by the arterial switch operation are discussed, these include transposition of the great arteries with intact ventricular septum (TGA IVS), TGA associated with a ventricular septal defect (TGA VSD), double-outlet right ventricle with subpulmonary VSD (DORV VSD), and TGA or DORV with VSD associated with coarctation. Double discordance with VSD, which is currently treated by double switch or Rastelli and atrial switch and which probably represents, in our department, the only remaining indication for atrial switch, is not discussed. Also, we exclude TGA associated with pulmonary stenosis, which is treated by Rastelli or REV operation.

  11. Magnetic switching

    NASA Astrophysics Data System (ADS)

    Kirbie, H. C.

    1989-04-01

    Magnetic switching is a pulse compression technique that uses a saturable inductor (reactor) to pass pulses of energy between two capacitors. A high degree of pulse compression can be achieved in a network when several of these simple, magnetically switched circuits are connected in series. Individual inductors are designed to saturate in cascade as a pulse moves along the network. The technique is particularly useful when a single-pulse network must be very reliable or when a multi-pulse network must operate at a high pulse repetition frequency (PRF). Today, magnetic switches trigger spark gaps, sharpen the risetimes of high energy pulses, power large lasers, and drive high PRF linear induction accelerators. This paper will describe the technique of magnetic pulse compression using simple networks and design equations. A brief review of modern magnetic materials and of their role in magnetic switch design will be presented.

  12. Acceleration switch

    DOEpatents

    Abbin, J.P. Jr.; Devaney, H.F.; Hake, L.W.

    1979-08-29

    The disclosure relates to an improved integrating acceleration switch of the type having a mass suspended within a fluid filled chamber, with the motion of the mass initially opposed by a spring and subsequently not so opposed.

  13. Acceleration switch

    DOEpatents

    Abbin, Jr., Joseph P.; Devaney, Howard F.; Hake, Lewis W.

    1982-08-17

    The disclosure relates to an improved integrating acceleration switch of the type having a mass suspended within a fluid filled chamber, with the motion of the mass initially opposed by a spring and subsequently not so opposed.

  14. Nucleosome Switches

    NASA Astrophysics Data System (ADS)

    Schwab, David J.; Bruinsma, Robijn F.; Rudnick, Joseph; Widom, Jonathan

    2008-06-01

    We present a statistical-mechanical model for the positioning of nucleosomes along genomic DNA molecules as a function of the strength of the binding potential and the chemical potential of the nucleosomes. We show that a significant section of the DNA is composed of two-level nucleosome switching regions where the nucleosome distribution undergoes a localized, first-order transition. The location of the nucleosome switches shows a strong correlation with the location of gene-regulation regions.

  15. Nucleosome switches.

    PubMed

    Schwab, David J; Bruinsma, Robijn F; Rudnick, Joseph; Widom, Jonathan

    2008-06-06

    We present a statistical-mechanical model for the positioning of nucleosomes along genomic DNA molecules as a function of the strength of the binding potential and the chemical potential of the nucleosomes. We show that a significant section of the DNA is composed of two-level nucleosome switching regions where the nucleosome distribution undergoes a localized, first-order transition. The location of the nucleosome switches shows a strong correlation with the location of gene-regulation regions.

  16. Optical switch

    DOEpatents

    Reedy, Robert P.

    1987-01-01

    An optical switching device (10) is provided whereby light from a first glass fiber (16) or a second glass fiber (14) may be selectively transmitted into a third glass fiber (18). Each glass fiber is provided with a focusing and collimating lens system (26, 28, 30). In one mode of operation, light from the first glass fiber (16) is reflected by a planar mirror (36) into the third glass fiber (18). In another mode of operation, light from the second glass fiber (14) passes directly into the third glass fiber (18). The planar mirror (36) is attached to a rotatable table (32) which is rotated to provide the optical switching.

  17. Optical switch

    DOEpatents

    Reedy, R.P.

    1987-11-10

    An optical switching device is provided whereby light from a first glass fiber or a second glass fiber may be selectively transmitted into a third glass fiber. Each glass fiber is provided with a focusing and collimating lens system. In one mode of operation, light from the first glass fiber is reflected by a planar mirror into the third glass fiber. In another mode of operation, light from the second glass fiber passes directly into the third glass fiber. The planar mirror is attached to a rotatable table which is rotated to provide the optical switching. 3 figs.

  18. Optical switch

    DOEpatents

    Reedy, R.P.

    1985-01-18

    An optical switching device is provided whereby light from a first glass fiber or a second glass fiber may be selectively transmitted into a third glass fiber. Each glass fiber is provided with a focusing and collimating lens system. In one mode of operation, light from the first glass fiber is reflected by a planar mirror into the third glass fiber. In another mode of operation, light from the second glass fiber passes directly into the third glass fiber. The planar mirror is attached to a rotatable table which is rotated to provide the optical switching.

  19. X-ray crystal structures of Escherichia coli RNA polymerase with switch region binding inhibitors enable rational design of squaramides with an improved fraction unbound to human plasma protein

    PubMed Central

    Molodtsov, Vadim; Fleming, Paul R.; Eyermann, Charles J.; Ferguson, Andrew D.; Foulk, Melinda A.; McKinney, David C.; Masse, Craig E.; Buurman, Ed T.; Murakami, Katsuhiko S.

    2015-01-01

    Squaramides constitute a novel class of RNA polymerase inhibitors of which genetic evidence and computational modeling previously have suggested an inhibitory mechanism mediated by binding to the RNA polymerase switch region. An iterative chemistry program increased the fraction unbound to human plasma protein from below minimum detection levels, i.e. <1%, to 4~6%, while retaining biochemical potency. Since in vitro antimicrobial activity against an efflux-negative strain of Haemophilus influenzae was 4~8-fold higher, the combined improvement was at least 20~60-fold. Co-crystal structures of Escherichia coli RNA polymerase with two key squaramides showed displacement of the switch 2, predicted to interfere with the conformational change of clamp domain and/or with binding of non-template DNA, a mechanism akin to that of natural product myxopyronin. Furthermore, the structures confirmed the chemical features required for biochemical potency. The terminal isoxazole and benzyl rings bind into distinct relatively narrow, hydrophobic pockets and both are required for biochemical potency. In contrast, the linker composed of squarate and piperidine accesses different conformations in their respective co-crystal structures with RNA polymerase, reflecting its main role of proper orientation of the aforementioned terminal rings. These observations further explain the tolerance of hydrophilic substitutions in the linker region that was exploited to improve the fraction unbound to human plasma protein while retaining biochemical potency. PMID:25798859

  20. Effects of the T/L-type calcium channel blocker benidipine on albuminuria and plasma aldosterone concentration. A pilot study involving switching from L-type calcium channel blockers to benidipine.

    PubMed

    Tani, Shigemasa; Takahashi, Atsuhiko; Nagao, Ken; Hirayama, Atsushi

    2014-01-01

    Albuminuria and a high plasma aldosterone concentration (PAC) are prognosis factors predicting a poor outcome for cardiovascular disease. We examined here the effects of benidipine, a T/L-type calcium channel blocker (CCB), on albuminuria and PAC.Thirty-one patients with essential hypertension who received an L-type CCB and achieved the target blood pressure (BP) indicated by the Treatment Guidelines of the Japan Society of Hypertension (JSH2009) were investigated. The Ltype CCB under treatment was switched to benidipine at a dose in which equivalent BP reduction was expected. BP and estimated glomerular filtration rate at 6 months after switching to benidipine were not significantly different from those at baseline. The urinary-albumin-creatinine ratio (UACR) decreased significantly by 36.9% (P = 0.001). No significant change was observed in plasma renin activity (P = 0.063). The PAC of all patients decreased significantly by 11.8% (P = 0.002). When analyzed by daily doses of benidipine, the PAC appeared to have decreased in patients who received 4 mg per day of benidipine (n = 14), although statistical significance was not reached (P = 0.096). The PAC in patients who received 8 mg per day of benidipine (n =17) was significantly reduced by 13.2% (P = 0.017).In hypertensive patients whose BP is controlled by L-type CCB, switching to the T/L-type CCB benidipine maintained BP control and reduced UACR. In addition, the high dose of benidipine reduced the PAC independent of BP control. These results suggest the T/L-type CCB benidipine may contribute to cardio-renal protection in addition to lowering BP.

  1. Switching Transistor

    NASA Technical Reports Server (NTRS)

    1981-01-01

    Westinghouse Electric Corporation's D60T transistors are used primarily as switching devices for controlling high power in electrical circuits. It enables reduction in the number and size of circuit components and promotes more efficient use of energy. Wide range of application from a popcorn popper to a radio frequency generator for solar cell production.

  2. Switched power workshop. [Switched power electron guns

    SciTech Connect

    Palmer, R.B.

    1988-01-01

    This paper discusses the design of a switched power electron gun. Particular topics discussed are: vacuum photodiode switch; laser switched solid state diodes; gun performance; charging supply; and laser requirements. (LSP)

  3. A Simple Protein Precipitation-based Simultaneous Quantification of Lovastatin and Its Active Metabolite Lovastatin Acid in Human Plasma by Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry using Polarity Switching.

    PubMed

    Wujian, Ju; Kuan-Wei, Peng; Sihyung, Yang; Huijing, Sun; Mario, Sampson; Zhuo, Wang Michael

    2015-05-01

    Lovastatin is an anti-cholesterol lactone drug indicated for the treatment of hyperlipidemia and to reduce the risk of coronary heart disease. It is converted to the β-hydroxy acid form (lovastatin acid) in vivo, which is the major pharmacologically active metabolite. Here, we describe the development and validation of an ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS)-based method utilizing polarity switching for the simultaneous quantification of lovastatin and lovastatin acid in human plasma. Simple protein precipitation extraction and direct injection of the extracted samples without drying/reconstitution showed good recoveries of both analytes (~70%). The developed method exhibited satisfactory intra-day and inter-day accuracy and precision. The interconversion between lovastatin and lovastatin acid during sample preparation and storage was minimal (< 1.9%). The lower limits of quantification were 0.5 and 0.2 nM (or 0.2 and 0.084 ng/mL) for lovastatin and lovastatin acid, respectively, using only 50 μL of plasma during extraction. The validated method was successfully applied to analyze plasma samples obtained from a healthy human subject who enrolled in a clinical drug interaction study involving lovastatin.

  4. Determination of methotrexate and its metabolite 7-hydroxymethotrexate by direct injection of human plasma into a column-switching liquid chromatographic system using post-column photochemical reaction with fluorimetric detection.

    PubMed

    Yu, Z; Westerlund, D; Boos, K S

    1997-02-21

    A simple, sensitive and fully automated column-switching system by direct injection of plasma samples for determination of methotrexate and its metabolite 7-hydroxymethotrexate was developed. The system utilized a C8 alkyl-diol silica precolumn coupled with a LiChrospher RP-18 analytical column, followed by a photoreactor and fluorimetric detection. The photo-oxidative irradiation was accomplished at UV 254 nm in the presence of 0.1% hydrogen peroxide in the eluent. Studies showed that the fluorimetric response was influenced by the reaction time, the degree of the reactor's transparency and the choice of the working wavelengths. By optimizing the content of acetonitrile in the eluent, methotrexate can be separated from 7-hydroxymethotrexate completely. The method validation revealed quantitative recoveries (> or = 94%) with coefficients of variation < or = 4.4%. The limits of detection and quantitation for determination of methotrexate were 0.20 and 0.36 ng, respectively, corresponding to 2.0 and 3.6 ng/ml for an injection volume of 100 microliters. It was possible to enhance the sensitivity further by injecting larger plasma volumes, up to 500 microliters.

  5. Magnetic switching

    SciTech Connect

    Birx, D.; Cook, E.; Hawkins, S.; Poor, S.; Reginato, L.; Schmidt, J.; Smith, M.

    1983-06-01

    The paper discusses the development program in magnetic switching which was aimed at solving the rep-rate and reliability limitations of the ATA spark gaps. The end result has been a prototype physically very similar to the present Advanced Test Accelerator (ATA) pulse power unit but vastly superior in performance. This prototype, which is easily adaptable to the existing systems, has achieved a burst rep-rate of 20 kHz and an output voltage of 500 kV. A one-on-one substitution of the existing pulse power module would result in a 100 MeV accelerator. Furthermore, the high efficiency of the magnetic pulse compression stages has allowed CW operation of the prototype at one kilohertz opening up other applications for the pulse power. Performance and design details will be described.

  6. Transparent electrode for optical switch

    DOEpatents

    Goldhar, Julius; Henesian, Mark A.

    1986-01-01

    A low pressure gas electrode utilizing ionized gas in a glow discharge regime forms a transparent electrode for electro-optical switches. The transparent electrode comprises a low pressure gas region on both sides of the crystal. When the gas is ionized, e.g., by a glow discharge in the low pressure gas, the plasma formed is a good conductor. The gas electrode acts as a highly uniform conducting electrode. Since the plasma is transparent to a high energy laser beam passing through the crystal, the electrode is a transparent electrode. A crystal exposed from two sides to such a plasma can be charged up uniformly to any desired voltage. The plasma can be created either by the main high voltage pulser used to charge up the crystal or by auxiliary discharges or external sources of ionization. A typical configuration utilizes 10 torr argon in the discharge region adjacent to each crystal face.

  7. Switch Transcripts in Immunoglobulin Class Switching

    NASA Astrophysics Data System (ADS)

    Lorenz, Matthias; Jung, Steffen; Radbruch, Andreas

    1995-03-01

    B cells can exchange gene segments for the constant region of the immunoglobulin heavy chain, altering the class and effector function of the antibodies that they produce. Class switching is directed to distinct classes by cytokines, which induce transcription of the targeted DNA sequences. These transcripts are processed, resulting in spliced "switch" transcripts. Switch recombination can be directed to immunoglobulin G1 (IgG1) by the heterologous human metallothionein II_A promoter in mutant mice. Induction of the structurally conserved, spliced switch transcripts is sufficient to target switch recombination to IgG1, whereas transcription alone is not.

  8. Latching relay switch assembly

    DOEpatents

    Duimstra, Frederick A.

    1991-01-01

    A latching relay switch assembly which includes a coil section and a switch or contact section. The coil section includes at least one permanent magnet and at least one electromagnet. The respective sections are, generally, arranged in separate locations or cavities in the assembly. The switch is latched by a permanent magnet assembly and selectively switched by an overriding electromagnetic assembly.

  9. Comment on “Early stage time evolution of a dense nanosecond microdischarge used in fast optical switching applications” [Phys. Plasmas 22, 123518 (2015)

    SciTech Connect

    Bataller, A. Koulakis, J.; Pree, S.; Putterman, S.

    2016-03-15

    In an effort to understand the opaque nature of high-voltage nanosecond microdischarges and their ability to block 532 nm nanosecond laser pulses, as demonstrated by Bataller et al. [Appl. Phys. Lett. 105, 223501 (2014)], Levko and Raja have published a paper [Phys. Plasmas 22, 123518 (2015)] which simulates spark discharges in 1 bar of xenon gas. At this ambient pressure, Levko and Raja simulate final electron densities much too low to explain the observed opacity and conclude the probing laser generates the requisite ionization for self-blocking. However, the experimental findings of Bataller et al. showed opacity being reached at 10 bar, an order of magnitude larger than the pressure simulated by Levko and Raja. Furthermore, Bataller et al. showed the spark remained opaque for very low laser intensities, insufficient to cause any significant ionization. Although the simulation performed by Levko and Raja could have merit at 1 bar, it is not an appropriate comparison to the regime studied by Bataller et al.

  10. Temporal switching jitter in photoconductive switches

    SciTech Connect

    GAUDET,JOHN A.; SKIPPER,MICHAEL C.; ABDALLA,MICHAEL D.; AHERN,SEAN M.; MAR,ALAN; LOUBRIEL,GUILLERMO M.; ZUTAVERN,FRED J.; O'MALLEY,MARTIN W.; HELGESON,WESLEY D.; ROMERO,SAMUEL P.

    2000-04-13

    This paper reports on a recent comparison made between the Air Force Research Laboratory (AFRL) gallium arsenide, optically-triggered switch test configuration and the Sandia National Laboratories (SNL) gallium arsenide, optically-triggered switch test configuration. The purpose of these measurements was to compare the temporal switch jitter times. It is found that the optical trigger laser characteristics are dominant in determining the PCSS jitter.

  11. Latching micro optical switch

    DOEpatents

    Garcia, Ernest J; Polosky, Marc A

    2013-05-21

    An optical switch reliably maintains its on or off state even when subjected to environments where the switch is bumped or otherwise moved. In addition, the optical switch maintains its on or off state indefinitely without requiring external power. External power is used only to transition the switch from one state to the other. The optical switch is configured with a fixed optical fiber and a movable optical fiber. The movable optical fiber is guided by various actuators in conjunction with a latching mechanism that configure the switch in one position that corresponds to the on state and in another position that corresponds to the off state.

  12. Selection and validation of antibody clones against IgG and IgA subclasses in switched memory B-cells and plasma cells.

    PubMed

    Blanco, Elena; Perez-Andres, Martin; Sanoja-Flores, Luzalba; Wentink, Marjolein; Pelak, Ondrej; Martín-Ayuso, Marta; Grigore, Georgiana; Torres-Cañizales, Juan; López-Granados, Eduardo; Kalina, Tomas; der Burg, Mirjam Van; Arriba-Méndez, Sonia; Cruz, Santiago Santa; Puig, Noemí; van Dongen, Jacques J M; Orfao, Alberto

    2017-09-28

    The clinical value of assessing immunoglobulin (Ig)G and IgA subclasses in addition to the isotypes of soluble Igs in serum has been well established. >20years ago, the International Union of Immunological Societies and the World Health Organization performed collaborative studies in order to validate antibody (Ab) clones for the detection of IgG and IgA subclasses for a broad range of laboratory assays, but except for flow cytometry. Here we analyzed the performance of commercially available Ab clones to detect IgG and IgA subclasses in memory B-cells and plasma cells (PCs) by flow cytometry. In a first step, 28 Ab clones were evaluated in peripheral blood from healthy donors. Only 17/28 clones showed reactivity against IgG and IgA subclasses expressed on the B-cell and PC surface membrane, including Ab clones for IgG1 (SAG1, HP6188, HP6001 and HP6186), IgG2 (SAG2, HP6014 and HP6002), IgG3 (SAG3, HP6095 and HP6050), IgG4 (SAG4), IgA1 (SAA1, H69-11.4 and B3506B4) and IgA2 (SAA2, 2E2, and A9604D2). In a second step, for each Ig subclass a single clone was selected according to its specificity and fluorescence intensity (resolution power), for further more detailed validation (SAG1, SAG2, SAG3, SAG4, SAA1 and SAA2). This validation process was carried out in 4 different laboratories by testing the selected Ab clones in human peripheral blood, bone marrow and tonsil samples, using different staining protocols (e.g. surface membrane and/or cytoplasmic staining). All selected Ab clones displayed strong positivity, high specificity and optimal resolution between negative and positive cells. Alternative Ab clones were also validated. Thus, our results show the feasibility of using the validated Ig subclass Ab clones in combination with other B cell-associated markers for detailed dissection of the memory B-cell and PC compartments that express distinct Ig subclasses in different human tissues. Copyright © 2017. Published by Elsevier B.V.

  13. Oversized interference microwave switches with distributed power of a switching wave

    NASA Astrophysics Data System (ADS)

    Artemenko, S. N.; Gorev, S. A.; Igumnov, V. S.

    2017-05-01

    These are the results of research of the oversized (multimode) interference microwave switch at operating mode TE01. The switch was produced from two H-plane T-junctions being connected to each other through straight arms (series connection). Two types of oversized tees were considered. One was based on an oversized waveguide with 25×58 mm2 in cross-section and another was a package of regular H-tees operating at TE10 mode with a mutual switched arm. The operating frequency was 9.15 GHz. The conducted simulation showed the conditions of the “proper” TE01 mode at “open” and “close” states of the switch. Moreover, the relations between the arm’ lengths and field intensity distribution were compared with the similar relations of a regular cascade microwave plasma switch. In additional, experiments were carried out at low power level.

  14. Heat Switches for ADRs

    NASA Technical Reports Server (NTRS)

    DiPirro, M. J.; Shirron, P. J.

    2014-01-01

    Heat switches are key elements in the cyclic operation of Adiabatic Demagnetization Refrigerators (ADRs). Several of the types of heat switches that have been used for ADRs are described in this paper. Key elements in selection and design of these switches include not only ON/OFF switching ratio, but also method of actuation, size, weight, and structural soundness. Some of the trade-off are detailed in this paper.

  15. Heat switches for ADRs

    NASA Astrophysics Data System (ADS)

    DiPirro, M. J.; Shirron, P. J.

    2014-07-01

    Heat switches are key elements in the cyclic operation of Adiabatic Demagnetization Refrigerators (ADRs). Several of the types of heat switches that have been used for ADRs are described in this paper. Key elements in selection and design of these switches include not only ON/OFF switching ratio, but also method of actuation, size, weight, and structural soundness. Some of the trade-off are detailed in this paper.

  16. Remote switch actuator

    DOEpatents

    Haas, Edwin Gerard; Beauman, Ronald; Palo, Jr., Stefan

    2013-01-29

    The invention provides a device and method for actuating electrical switches remotely. The device is removably attached to the switch and is actuated through the transfer of a user's force. The user is able to remain physically removed from the switch site obviating need for protective equipment. The device and method allow rapid, safe actuation of high-voltage or high-current carrying electrical switches or circuit breakers.

  17. Apollo Ring Optical Switch

    SciTech Connect

    Maestas, J.H.

    1987-03-01

    An optical switch was designed, built, and installed at Sandia National Laboratories in Albuquerque, New Mexico, to facilitate the integration of two Apollo computer networks into a single network. This report presents an overview of the optical switch as well as its layout, switch testing procedure and test data, and installation.

  18. Simultaneous Determination of Celecoxib, Erlotinib, and its Metabolite Desmethyl-Erlotinib (OSI-420) in Rat Plasma by Liquid chromatography/Tandem Mass Spectrometry with Positive/Negative Ion-Switching Electrospray Ionisation.

    PubMed

    Thappali, Satheeshmanikandan R S; Varanasi, Kanthikiran; Veeraraghavan, Sridhar; Arla, Rambabu; Chennupati, Sandhya; Rajamanickam, Madheswaran; Vakkalanka, Swaroop; Khagga, Mukkanti

    2012-01-01

    A new method for the simultaneous determination of celecoxib, erlotinib, and its active metabolite desmethyl-erlotinib (OSI-420) in rat plasma, by liquid chromatography/tandem mass spectrometry with positive/negative ion-switching electrospray ionization mode, was developed and validated. Protein precipitation with methanol was selected as the method for preparing the samples. The analytes were separated on a reverse-phase C(18) column (50mm×4.6mm i.d., 3μ) using methanol: 2 mM ammonium acetate buffer, and pH 4.0 as the mobile phase at a flow rate 0.8 mL/min. Sitagliptin and Efervirenz were used as the internal standards for quantification. The determination was carried out on a Theremo Finnigan Quantam ultra triple-quadrupole mass spectrometer, operated in selected reaction monitoring (SRM) mode using the following transitions monitored simultaneously: positive m/z 394.5→278.1 for erlotinib, m/z 380.3→278.1 for desmethyl erlotinib (OSI-420), and negative m/z -380.1→ -316.3 for celecoxib. The limits of quantification (LOQs) were 1.5 ng/mL for Celecoxib, erlotinib, and OSI-420. Within- and between-day accuracy and precision of the validated method were within the acceptable limits of < 15% at all concentrations. The quantitation method was successfully applied for the simultaneous estimation of celecoxib, erlotinib, and desmethyl erlotinib in a pharmacokinetic study in Wistar rats.

  19. REMOTE CONTROLLED SWITCHING DEVICE

    DOEpatents

    Hobbs, J.C.

    1959-02-01

    An electrical switching device which can be remotely controlled and in which one or more switches may be accurately operated at predetermined times or with predetermined intervening time intervals is described. The switching device consists essentially of a deck, a post projecting from the deck at right angles thereto, cam means mounted for rotation around said posts and a switch connected to said deck and actuated by said cam means. Means is provided for rotating the cam means at a constant speed and the switching apparatus is enclosed in a sealed container with external adjusting means and electrical connection elements.

  20. On the Switching Control

    NASA Astrophysics Data System (ADS)

    Balas, Valentina E.; Balas, Marius M.

    2009-04-01

    The paper is discussing the measures able to reject the instability that may unexpectedly appear in particular conditions, in switching controllers applications. The switching controllers' effect is explained by the combined effects of the unsuitable choice of the switching moments (in the first or third quadrants of the phase trajectory of the switching error) and of the temporal aliasing that can distort the digital control systems when the sampling rate is close to the frequency of the oscillations that are produced by the commutation. The correct switching moments are located into the second and fourth quadrants of the phase trajectory of the switching error, but an active preparation of the commutation may be simply achieved by using a tracking controller, that is driving the output of open loop controller to follow the output of the close loop controller, permanently minimizing the switching error. Simulations issued from a dc driver speed controller and from an aircraft are provided.

  1. Optoelectronic techniques for broadband switching

    NASA Astrophysics Data System (ADS)

    Su, S. F.; Jou, L.; Lenart, J.

    1988-01-01

    Optoelectronic switching employs a hybrid optical/electronic principle to perform the switching function and is applicable for either analog broadband or high-bit rate digital switching. The major advantages of optoelectronic switching include high isolation, low crosstalk, small physical size, light weight, and low power consumption. These advantages make optoelectronic switching an excellent candidate for on-board satellite switching. This paper describes a number of optoelectronic switching architectures. System components required for implementing these switching architectures are discussed. Performance of these architectures are evaluated by calculating their crosstalk, isolation, insertion loss, matrix size, drive power, throughput, and switching speed. Technologies needed for monolithic optoelectronic switching are also identified.

  2. Two-dimensional modeling of x-ray output from switched foil implosions on Procyon

    NASA Astrophysics Data System (ADS)

    Bowers, R. L.; Nakafuji, G.; Greene, A. E.; McLenithan, K. D.; Peterson, D. L.; Roderick, N. F.

    1996-09-01

    A series of two-dimensional radiation magnetohydrodynamic calculations are presented of a Z-pinch implosion using a plasma flow switch. Results from a recent experiment using the high explosive driven generator Procyon, which delivered 16.5 MA to a plasma flow switch and switched about 15 MA into a static load, are used to study the implosion of a 29 mg load foil [J. H. Goforth et al., ``Review of the Procyon Explosive Pulsed Power System,'' in Ninth IEEE Pulsed Power Conference, June 1993, Albuquerque, edited by K. R. Prestwich and W. L. Baker (Institute of Electrical and Electronics Engineers, Piscataway, NJ, 1993), p. 36]. The interaction of the switch with the load plasma and the effects of background plasma on the total radiation output is examined. Models which assume ideal switching are also included. Also included are the effects of perturbations in the load plasma which may be associated with initial vaporization of the load foil. If the background plasma density in the switch region and in the load region does not affect the dynamics, the pinch is predicted to produce a total radiation output of about 4 MJ. Including perturbations of the load plasma associated with switching and assuming a background plasma density after switching in excess of 10-7 g/cm3 results in a total output from the pinch of about 0.6 MJ.

  3. Procyon experiments utilizing foil-fuse opening switches

    SciTech Connect

    Rickel, D.G.; Lindemuth, I.R.; Reinovsky, R.E.; Brownell, J.H.; Goforth, J.H.; Greene, A.E.; Kruse, H.W.; Oona, H.; Parker, J.V.; Turchi, P.J.

    1991-01-01

    The Los Alamos National Laboratory has applied the explosive magnetic flux compression generator (FCG) technology to the high-energy foil-implosion project, Trailmaster, to reach energy levels unattainable by other methods under current budget constraints. A required component for FCG systems is a power-conditioning stage that matches the slow risetime of the energy source with the fast-risetime requirements of the foil-implosion load. Currently, the Trailmaster concept is based on a two-step process of combining an intermediate power compression stage with a plasma flow switch (PFS) that will deliver energy to an imploding foil on the order of 100 ns. The intermediate power compression stage, which is the main emphasis of this report, consists of an energy storage inductor loaded by the FCG (the energy sauce) and an associated opening and closing switch. In our Procyon testing series, a subtask of the Trailmaster project, we have explored two approaches for opening and closing switches. One uses an explosive opening switch (EFF) and a detonator-initiated closing switch, the topic of another paper at this conference, and the other a resistive fuse opening switch a surface tracking closing switch (STS), the subject of this presentation. This latter concept was successfully tested last summer with a complete plasma flow switch assembly except the dynamic implosion foil was replaced by a rigid passive inductive load. We present data on the performance of the fuse opening switch, the surface tracking closing switch, and the plasma flow switch. 7 refs., 9 figs.

  4. Monolithic Microwave Switching Matrix

    NASA Technical Reports Server (NTRS)

    Fujikawa, Gene; Ch'en, Daniel R.; Petersen, Wendell C.

    1989-01-01

    Gallium arsenide integrated-circuit chip switches any of three microwave input signals to any of three output ports. Measuring 4.9 mm on side, chip contains nine field-effect transistor (FET) crosspoint switches. Housed in custom-designed package with standard connectors for easy integration into system. FET's on chip operated as passive switches and consume no static power and insignificant amounts of switching power. Chip module cascades with similar modules into large arrays handling as many as 100 inputs and 100 outputs. Applications include switching and routing vast amounts of data between computers at extremely high speed. On communications satellite, chip switches microwave signals to and from Earth stations and other satellites.

  5. Effective switching frequency multiplier inverter

    DOEpatents

    Su, Gui-Jia; Peng, Fang Z.

    2007-08-07

    A switching frequency multiplier inverter for low inductance machines that uses parallel connection of switches and each switch is independently controlled according to a pulse width modulation scheme. The effective switching frequency is multiplied by the number of switches connected in parallel while each individual switch operates within its limit of switching frequency. This technique can also be used for other power converters such as DC/DC, AC/DC converters.

  6. Simultaneous determination of lovastatin and its metabolite lovastatin acid in rat plasma using UPLC-MS/MS with positive/negative ion-switching electrospray ionization: Application to a pharmacokinetic study of lovastatin nanosuspension.

    PubMed

    Guo, Mengran; Zhao, Longshan; Li, Mo; Fu, Qiang; Pu, Xiaohui; Liu, Bingyang; He, Zhonggui; Yang, Li

    2016-06-15

    Lovastatin (LOV) is an antihyperlipidemic agent which exhibits low bioavailability due to its poor solubility. Therefore, a nanosuspension (NS) was developed as an efficient strategy to improve its oral bioavailability. To evaluate the pharmacokinetics of LOV-NS, a novel, sensitive, and rapid UPLC-MS/MS method was developed and validated for the simultaneous determination of LOV and its metabolite lovastatin acid (LOVA) in rat plasma. Simvastatin (IS) was chosen as the internal standard, and a liquid-liquid extraction method was used to isolate LOV and LOVA from biological matrices. The analytes were analyzed on an Acquity UPLC BEH C18 column, and a gradient program was applied at a flow rate of 0.2mL/min. Then, a tandem quadrupole mass spectrometer coupled with a positive/negative ion-switching electrospray ionization interface was employed to detect the analytes. Quantitation of the analytes was performed in the multiple reaction monitoring mode to monitor the transitions of m/z 427.1→325.0 for LOV and m/z 441.1→325.0 for IS in the positive ion mode and m/z 421.0→101.0 for LOVA in the negative ion mode, respectively. The method was validated over the concentration range 0.25-500ng/mL (r(2)≥0.99) for both LOV and LOVA. The intra-day and inter-day precision (RSD%) of LOV and LOVA were less than 12.87% and the accuracy (RE%) was less than 5.22%. The average extraction recoveries were 90.1% and 91.9% for LOV and LOVA, and the matrix effects were found to be between 85% and 115%. The stability study showed that both analytes were stable during the experiment. Finally, this method has been successfully applied to a pharmacokinetic study in rats following a single oral dose of 10mg/kg LOV-NS. Copyright © 2016 Elsevier B.V. All rights reserved.

  7. Double-Bounce Switching

    DTIC Science & Technology

    1983-06-01

    module. Adjustments provided to investigate double- bounce switching are noted. limitation is at a higher level and occurs in the conventionally...To be presented at the 4th IEEE PUlsed Power Conference, June 6-8, 1983, Albuquerque, NM. DOUBLE- BOUNCE SWITCHING* George B. Frazier and Steven R...Ashby Physics International Company 2700 Merced Street San Leandro, California 94577 Abstract Double- bounce switching is a technique for

  8. Avalanche Photoconductive Switching

    DTIC Science & Technology

    1989-06-01

    held off across the switch. In our case this corresponds to 70 kV/cm and is limited by surface flashover . The pulse length is determined by the...off across the gap of the switch, which in turn appears to be limited by surface flashover . There appears to be a threshold electric field of 20-60...and understand this mode of operation. Introduction Laser activated photoconductive switching in semiconductors is a promising technology for high

  9. Thermally actuated thermionic switch

    DOEpatents

    Barrus, Donald M.; Shires, Charles D.

    1988-01-01

    A thermally actuated thermionic switch which responds to an increase of temperature by changing from a high impedance to a low impedance at a predictable temperature set point. The switch has a bistable operation mode switching only on temperature increases. The thermionic material may be a metal which is liquid at the desired operation temperature and held in matrix in a graphite block reservoir, and which changes state (ionizes, for example) so as to be electrically conductive at a desired temperature.

  10. Thermally actuated thermionic switch

    DOEpatents

    Barrus, D.M.; Shires, C.D.

    1982-09-30

    A thermally actuated thermionic switch which responds to an increase of temperature by changing from a high impedance to a low impedance at a predictable temperature set point. The switch has a bistable operation mode switching only on temperature increases. The thermionic material may be a metal which is liquid at the desired operation temperature and held in matrix in a graphite block reservoir, and which changes state (ionizes, for example) so as to be electrically conductive at a desired temperature.

  11. Solid state switch

    DOEpatents

    Merritt, Bernard T.; Dreifuerst, Gary R.

    1994-01-01

    A solid state switch, with reverse conducting thyristors, is designed to operate at 20 kV hold-off voltage, 1500 A peak, 1.0 .mu.s pulsewidth, and 4500 pps, to replace thyratrons. The solid state switch is more reliable, more economical, and more easily repaired. The switch includes a stack of circuit card assemblies, a magnetic assist and a trigger chassis. Each circuit card assembly contains a reverse conducting thyristor, a resistor capacitor network, and triggering circuitry.

  12. AC magnetohydrodynamic microfluidic switch

    SciTech Connect

    Lemoff, A V; Lee, A P

    2000-03-02

    A microfluidic switch has been demonstrated using an AC Magnetohydrodynamic (MHD) pumping mechanism in which the Lorentz force is used to pump an electrolytic solution. By integrating two AC MHD pumps into different arms of a Y-shaped fluidic circuit, flow can be switched between the two arms. This type of switch can be used to produce complex fluidic routing, which may have multiple applications in {micro}TAS.

  13. Alarm toe switch

    DOEpatents

    Ganyard, Floyd P.

    1982-01-01

    An alarm toe switch inserted within a shoe for energizing an alarm circuit n a covert manner includes an insole mounting pad into which a miniature reed switch is fixedly molded. An elongated slot perpendicular to the reed switch is formed in the bottom surface of the mounting pad. A permanent cylindrical magnet positioned in the forward portion of the slot with a diameter greater than the pad thickness causes a bump above the pad. A foam rubber block is also positioned in the slot rearwardly of the magnet and holds the magnet in normal inoperative relation. A non-magnetic support plate covers the slot and holds the magnet and foam rubber in the slot. The plate minimizes bending and frictional forces to improve movement of the magnet for reliable switch activation. The bump occupies the knuckle space beneath the big toe. When the big toe is scrunched rearwardly the magnet is moved within the slot relative to the reed switch, thus magnetically activating the switch. When toe pressure is released the foam rubber block forces the magnet back into normal inoperative position to deactivate the reed switch. The reed switch is hermetically sealed with the magnet acting through the wall so the switch assembly S is capable of reliable operation even in wet and corrosive environments.

  14. Reusable fast opening switch

    DOEpatents

    Van Devender, J.P.; Emin, D.

    1983-12-21

    A reusable fast opening switch for transferring energy, in the form of a high power pulse, from an electromagnetic storage device such as an inductor into a load. The switch is efficient, compact, fast and reusable. The switch comprises a ferromagnetic semiconductor which undergoes a fast transition between conductive and metallic states at a critical temperature and which undergoes the transition without a phase change in its crystal structure. A semiconductor such as europium rich europhous oxide, which undergoes a conductor to insulator transition when it is joule heated from its conductor state, can be used to form the switch.

  15. Reusable fast opening switch

    DOEpatents

    Van Devender, John P.; Emin, David

    1986-01-01

    A reusable fast opening switch for transferring energy, in the form of a high power pulse, from an electromagnetic storage device such as an inductor into a load. The switch is efficient, compact, fast and reusable. The switch comprises a ferromagnetic semiconductor which undergoes a fast transition between conductive and insulating states at a critical temperature and which undergoes the transition without a phase change in its crystal structure. A semiconductor such as europium rich europhous oxide, which undergoes a conductor to insulator transition when it is joule heated from its conductor state, can be used to form the switch.

  16. Platform switching and bone platform switching.

    PubMed

    Carinci, Francesco; Brunelli, Giorgio; Danza, Matteo

    2009-01-01

    Bone platform switching involves an inward bone ring in the coronal part of the implant that is in continuity with the alveolar bone crest. Bone platform switching is obtained by using a dental fixture with a reverse conical neck. A retrospective study was performed to evaluate the effectiveness of conventional vs reverse conical neck implants. In the period between May 2004 and November 2007, 86 patients (55 females and 31 males; median age, 53 years) were operated and 234 implants were inserted: 40 and 194 were conventional vs reverse conical neck implants, respectively. Kaplan-Meier algorithm and Cox regression were used to detect those variables associated with the clinical outcome. No differences in survival and success rates were detected between conventional vs reverse conical neck implants alone or in combination with any of the studied variables. Although bone platform switching leads to several advantages, no statistical difference in alveolar crest resorption is detected in comparison with reverse conical neck implants. We suppose that the proximity of the implant abutment junction to the alveolar crestal bone gives no protection against the microflora contained in the micrograph. Additional studies on larger series and a combination of platform switching and bone platform switching could lead to improved clinical outcomes.

  17. Asymmetrical Switch Costs in Children

    ERIC Educational Resources Information Center

    Ellefson, Michelle R.; Shapiron, Laura R.; Chater, Nick

    2006-01-01

    Switching between tasks produces decreases in performance as compared to repeating the same task. Asymmetrical switch costs occur when switching between two tasks of unequal difficulty. This asymmetry occurs because the cost is greater when switching to the less difficult task than when switching to the more difficult task. Various theories about…

  18. Optically switched submillimeter-wave oscillator

    NASA Astrophysics Data System (ADS)

    Spencer, Michael G.; Tang, Xiao

    1994-02-01

    There exists a critical need for efficient local oscillators for heterodyne mixers operating in the 300 to 3000 GHz region. Applications include space-based submillimeter wave imaging arrays, airborne atmosphere spectroscopy, all-weather imaging radar, non-destructive testing, plasma diagnostics, weapon and contraband detection, and communications. In order to address these problems, we propose a novel low power semiconductor device which uses time delays from a common optical pulse train to achieve a much higher frequency electrical pulse train, which contains a strong component and appreciable power of the desired submillimeter-wave harmonic for the output and which can be readily coupled electrically or radiatively to a receiver. In our effort, we developed a concept of linear array of ten optical switches. The microwave output from the switches can be in the 100 - 200 GHz frequency range. In order to implement this concept, a single photo-conductive switch of polycrystalline InGaAs was fabricated and tested.

  19. Quantum cryptography without switching.

    PubMed

    Weedbrook, Christian; Lance, Andrew M; Bowen, Warwick P; Symul, Thomas; Ralph, Timothy C; Lam, Ping Koy

    2004-10-22

    We propose a new coherent state quantum key distribution protocol that eliminates the need to randomly switch between measurement bases. This protocol provides significantly higher secret key rates with increased bandwidths than previous schemes that only make single quadrature measurements. It also offers the further advantage of simplicity compared to all previous protocols which, to date, have relied on switching.

  20. Power-Switching Circuit

    NASA Technical Reports Server (NTRS)

    Praver, Gerald A.; Theisinger, Peter C.; Genofsky, John

    1987-01-01

    Functions of circuit breakers, meters, and switches combined. Circuit that includes power field-effect transistors (PFET's) provides on/off switching, soft starting, current monitoring, current tripping, and protection against overcurrent for 30-Vdc power supply at normal load currents up to 2 A. Has no moving parts.

  1. Reflective HTS switch

    DOEpatents

    Martens, J.S.; Hietala, V.M.; Hohenwarter, G.K.G.

    1994-09-27

    A HTS (High Temperature Superconductor) switch includes a HTS conductor for providing a superconducting path for an electrical signal and an serpentine wire actuator for controllably heating a portion of the conductor sufficiently to cause that portion to have normal, and not superconducting, resistivity. Mass of the portion is reduced to decrease switching time. 6 figs.

  2. Reflective HTS switch

    SciTech Connect

    Martens, Jon S.; Hietala, Vincent M.; Hohenwarter, Gert K. G.

    1994-01-01

    A HTS switch includes a HTS conductor for providing a superconducting path for an electrical signal and an serpentine wire actuator for controllably heating a portion of the conductor sufficiently to cause that portion to have normal, and not superconducting, resistivity. Mass of the portion is reduced to decrease switching time.

  3. Manually operated coded switch

    DOEpatents

    Barnette, Jon H.

    1978-01-01

    The disclosure relates to a manually operated recodable coded switch in which a code may be inserted, tried and used to actuate a lever controlling an external device. After attempting a code, the switch's code wheels must be returned to their zero positions before another try is made.

  4. A Novel Molecular Switch

    PubMed Central

    Daber, Robert; Lewis, Mitchell

    2009-01-01

    Transcriptional regulation is a fundamental process for regulating the flux of all metabolic pathways. For the last several decades, the lac operon has served as a valuable model for studying transcription. More recently, the switch that controls the operon has also been successfully adapted to function in mammalian cells. Here we describe how, using directed evolution, we have created a novel switch that recognizes an asymmetric operator sequence. The new switch has a repressor with altered headpiece domains for operator recognition, and a redesigned dimer interface to create a heterodimeric repressor. Quite unexpectedly, the heterodimeric switch functions better than the natural system. It can repress more tightly than the naturally occurring switch of the lac operon; it is less leaky and can be induced more efficiently. Ultimately these novel repressors could be evolved to recognize eukaryotic promoters and used to regulate gene expression in mammalian systems. PMID:19540845

  5. Erected mirror optical switch

    DOEpatents

    Allen, James J.

    2005-06-07

    A microelectromechanical (MEM) optical switching apparatus is disclosed that is based on an erectable mirror which is formed on a rotatable stage using surface micromachining. An electrostatic actuator is also formed on the substrate to rotate the stage and mirror with a high angular precision. The mirror can be erected manually after fabrication of the device and used to redirect an incident light beam at an arbitrary angel and to maintain this state in the absence of any applied electrical power. A 1.times.N optical switch can be formed using a single rotatable mirror. In some embodiments of the present invention, a plurality of rotatable mirrors can be configured so that the stages and mirrors rotate in unison when driven by a single micromotor thereby forming a 2.times.2 optical switch which can be used to switch a pair of incident light beams, or as a building block to form a higher-order optical switch.

  6. PLASMA GENERATOR

    DOEpatents

    Wilcox, J.M.; Baker, W.R.

    1963-09-17

    This invention is a magnetohydrodynamic device for generating a highly ionized ion-electron plasma at a region remote from electrodes and structural members, thus avoiding contamination of the plasma. The apparatus utilizes a closed, gas-filled, cylindrical housing in which an axially directed magnetic field is provided. At one end of the housing, a short cylindrical electrode is disposed coaxially around a short axial inner electrode. A radial electrical discharge is caused to occur between the inner and outer electrodes, creating a rotating hydromagnetic ionization wave that propagates aiong the magnetic field lines toward the opposite end of the housing. A shorting switch connected between the electrodes prevents the wave from striking the opposite end of the housing. (AEC)

  7. Plasma displays

    SciTech Connect

    Sobel, A.

    1991-12-01

    Plasma displays make use of lightly ionized glow discharges to produce light, perform switching and selection functions, or both. Both the negative glow and the positive column are used. Color can be attained by using UV from the discharge to stimulate phosphors. The adroit use of priming can reduce the number of drive circuits required - an advantage unique in the display art to plasma devices. Short voltage pulses can improve the efficacy of positive-column devices. Short voltage pulses can improve the efficacy of positive-column devices. The gas discharge can be used as a source of electrons, which can then excite cathodoluminescent phosphors in a variety of colors. It can also be used as a selection means for liquid-crystal displays. In this paper a wide variety of device configurations, using both unidirectional and bidirectional pulse excitations, is described.

  8. Improved Lifetime High Voltage Switch Electrode.

    DTIC Science & Technology

    2014-09-26

    and T.R. Burkes, "Erosion of Spark Gap Electrodes", IEEE Trans. Plasma Sci., PS-8, 149, (1980). 5. L.B. Gordon, M. Kristiansen, M.O. Hagler, H.C...Kirbie, R.M. Ness, L.L. Hatfield and 3.N. Marx, "Material Studies in a High Energy Spark Gap", IEEE Trans. Plasma Sci., PS-10, 286, (1982). 6. A.L...identify by block number) Spark switches, electrodes, ion implantation. _. / 20. ABSTRACT (Cqntnu* on ,.as maide Ii necossery and Identify by block number

  9. Optical packet switching

    NASA Astrophysics Data System (ADS)

    Shekel, Eyal; Ruschin, Shlomo; Majer, Daniel; Levy, Jeff; Matmon, Guy; Koenigsberg, Lisa; Vecht, Jacob; Geron, Amir; Harlavan, Rotem; Shfaram, Harel; Arbel, Arnon; McDermott, Tom; Brewer, Tony

    2005-02-01

    We report here a scalable, multichassis, 6.3 terabit core router, which utilizes our proprietary optical switch. The router is commercially available and deployed in several customer sites. Our solution combines optical switching with electronic routing. An internal optical packet switching network interconnects the router"s electronic line cards, where routing and buffering functions take place electronically. The system architecture and performance will be described. The optical switch is based on Optical Phased Array (OPA) technology. It is a 64 x 64, fully non-blocking, optical crossbar switch, capable of switching in a fraction of a nanosecond. The basic principles of operation will be explained. Loss and crosstalk results will be presented, as well as the results of BER measurements of a 160 Gbps transmission through one channel. Basic principles of operation and measured results will be presented for the burst-mode-receivers, arbitration algorithm and synchronization. Finally, we will present some of our current research work on a next-generation optical switch. The technological issues we have solved in our internal optical packet network can have broad applicability to any global optical packet network.

  10. Optical Circuit Switched Protocol

    NASA Technical Reports Server (NTRS)

    Monacos, Steve P. (Inventor)

    2000-01-01

    The present invention is a system and method embodied in an optical circuit switched protocol for the transmission of data through a network. The optical circuit switched protocol is an all-optical circuit switched network and includes novel optical switching nodes for transmitting optical data packets within a network. Each optical switching node comprises a detector for receiving the header, header detection logic for translating the header into routing information and eliminating the header, and a controller for receiving the routing information and configuring an all optical path within the node. The all optical path located within the node is solely an optical path without having electronic storage of the data and without having optical delay of the data. Since electronic storage of the header is not necessary and the initial header is eliminated by the first detector of the first switching node. multiple identical headers are sent throughout the network so that subsequent switching nodes can receive and read the header for setting up an optical data path.

  11. Triggered vacuum flashover switch for high-power applications

    SciTech Connect

    Kellogg, J.C.; Boller, J.R.; Commisso, R.J.; Jenkins, D.J. ); Ford, R.D. ); Lupton, W.H. ); Shipman, J.D. Jr. )

    1991-11-01

    A command triggered, high-power, surface-flashover closing switch that operates in vacuum has been developed for use on a prototype inductive-storage pulsed power generator, Pawn. This vacuum flashover switch isolates the high-pressure-gas tamped wire fuse from a second opening switch. The switch consists of an insulating ring sandwiched between electrodes. Plasma and ultraviolet light from eight small spark discharges driven by a 5 keV pulse initiate a flashover across the switch insulator. The entire triggering unit resides inside one of Pawn's metallic conductors. The switch can be triggered after holding off voltage for {congruent}15 {mu}s. Normally, switch closure occurs at 22--45 kV. Time to closure at a voltage of {congruent}30 kV is {congruent}320 ns, with a typical jitter of {plus minus}50 ns. Peak current is typically {congruent}1 MA. Current density in the switch is approximately 25 kA/cm{sup 2}. The average risetime of the fuse output current pulse can be varied by a factor of 2 by triggering the switch at different closing voltages.

  12. Ferroelectric opening switches for large-scale pulsed power drivers.

    SciTech Connect

    Brennecka, Geoffrey L.; Rudys, Joseph Matthew; Reed, Kim Warren; Pena, Gary Edward; Tuttle, Bruce Andrew; Glover, Steven Frank

    2009-11-01

    Fast electrical energy storage or Voltage-Driven Technology (VDT) has dominated fast, high-voltage pulsed power systems for the past six decades. Fast magnetic energy storage or Current-Driven Technology (CDT) is characterized by 10,000 X higher energy density than VDT and has a great number of other substantial advantages, but it has all but been neglected for all of these decades. The uniform explanation for neglect of CDT technology is invariably that the industry has never been able to make an effective opening switch, which is essential for the use of CDT. Most approaches to opening switches have involved plasma of one sort or another. On a large scale, gaseous plasmas have been used as a conductor to bridge the switch electrodes that provides an opening function when the current wave front propagates through to the output end of the plasma and fully magnetizes the plasma - this is called a Plasma Opening Switch (POS). Opening can be triggered in a POS using a magnetic field to push the plasma out of the A-K gap - this is called a Magnetically Controlled Plasma Opening Switch (MCPOS). On a small scale, depletion of electron plasmas in semiconductor devices is used to affect opening switch behavior, but these devices are relatively low voltage and low current compared to the hundreds of kilo-volts and tens of kilo-amperes of interest to pulsed power. This work is an investigation into an entirely new approach to opening switch technology that utilizes new materials in new ways. The new materials are Ferroelectrics and using them as an opening switch is a stark contrast to their traditional applications in optics and transducer applications. Emphasis is on use of high performance ferroelectrics with the objective of developing an opening switch that would be suitable for large scale pulsed power applications. Over the course of exploring this new ground, we have discovered new behaviors and properties of these materials that were here to fore unknown. Some of

  13. Electromechanical magnetization switching

    SciTech Connect

    Chudnovsky, Eugene M.; Jaafar, Reem

    2015-03-14

    We show that the magnetization of a torsional oscillator that, in addition to the magnetic moment also possesses an electrical polarization, can be switched by the electric field that ignites mechanical oscillations at the frequency comparable to the frequency of the ferromagnetic resonance. The 180° switching arises from the spin-rotation coupling and is not prohibited by the different symmetry of the magnetic moment and the electric field as in the case of a stationary magnet. Analytical equations describing the system have been derived and investigated numerically. Phase diagrams showing the range of parameters required for the switching have been obtained.

  14. Sleep State Switching

    PubMed Central

    Saper, Clifford B.; Fuller, Patrick M.; Pedersen, Nigel P.; Lu, Jun; Scammell, Thomas E.

    2010-01-01

    We take for granted the ability to fall asleep or to snap out of sleep into wakefulness, but these changes in behavioral state require specific switching mechanisms in the brain that allow well-defined state transitions. In this review, we examine the basic circuitry underlying the regulation of sleep and wakefulness, and discuss a theoretical framework wherein the interactions between reciprocal neuronal circuits enable relatively rapid and complete state transitions. We also review how homeostatic, circadian, and allostatic drives help regulate sleep state switching, and discuss how breakdown of the switching mechanism may contribute to sleep disorders such as narcolepsy. PMID:21172606

  15. Photoconductive switch package

    DOEpatents

    Ca[rasp, George J

    2013-10-22

    A photoconductive switch is formed of a substrate that has a central portion of SiC or other photoconductive material and an outer portion of cvd-diamond or other suitable material surrounding the central portion. Conducting electrodes are formed on opposed sides of the substrate, with the electrodes extending beyond the central portion and the edges of the electrodes lying over the outer portion. Thus any high electric fields produced at the edges of the electrodes lie outside of and do not affect the central portion, which is the active switching element. Light is transmitted through the outer portion to the central portion to actuate the switch.

  16. SPARK GAP SWITCH

    DOEpatents

    Neal, R.B.

    1957-12-17

    An improved triggered spark gap switch is described, capable of precisely controllable firing time while switching very large amounts of power. The invention in general comprises three electrodes adjustably spaced and adapted to have a large potential impressed between the outer electrodes. The central electrode includes two separate elements electrically connected togetaer and spaced apart to define a pair of spark gaps between the end electrodes. Means are provided to cause the gas flow in the switch to pass towards the central electrode, through a passage in each separate element, and out an exit disposed between the two separate central electrode elements in order to withdraw ions from the spark gap.

  17. Photoconductive switch package

    DOEpatents

    Caporaso, George J.

    2015-10-27

    A photoconductive switch is formed of a substrate that has a central portion of SiC or other photoconductive material and an outer portion of cvd-diamond or other suitable material surrounding the central portion. Conducting electrodes are formed on opposed sides of the substrate, with the electrodes extending beyond the central portion and the edges of the electrodes lying over the outer portion. Thus any high electric fields produced at the edges of the electrodes lie outside of and do not affect the central portion, which is the active switching element. Light is transmitted through the outer portion to the central portion to actuate the switch.

  18. Solid state switch

    DOEpatents

    Merritt, B.T.; Dreifuerst, G.R.

    1994-07-19

    A solid state switch, with reverse conducting thyristors, is designed to operate at 20 kV hold-off voltage, 1,500 A peak, 1.0 [mu]s pulsewidth, and 4,500 pps, to replace thyratrons. The solid state switch is more reliable, more economical, and more easily repaired. The switch includes a stack of circuit card assemblies, a magnetic assist and a trigger chassis. Each circuit card assembly contains a reverse conducting thyristor, a resistor capacitor network, and triggering circuitry. 6 figs.

  19. Solar array switching unit

    NASA Technical Reports Server (NTRS)

    Craig, Jr., Calvin L. (Inventor)

    2000-01-01

    A solar array switching (SASU) unit (22) according to the present invention includes a control system (24), a solar cell array (26) and switch circuits (28). The SASU unit (22) is associated with a power card (30) for receiving an output from the array (26). The array (26) has a number (0.5Y) of rows (38) each of which includes a pair of cell strings (42) separated by one of the switch circuits (28). Each of the strings (42) includes a number (X) of cells in electrical series. The SASU (22) switches the array (26) between a short string configuration where the array (26) effectively includes Y strings of X length, and a long string configuration where the array (26) effectively includes 0.5Y strings of 2X length. The SASU (22) thereby facilitates the use of solar power for space missions where solar intensity, operating temperature or other factors vary significantly.

  20. Plasmonic enhanced ultrafast switch.

    SciTech Connect

    Subramania,Ganapathi Subramanian; Reno, John Louis; Passmore, Brandon Scott; Harris, Tom.; Shaner, Eric Arthur; Barrick, Todd A.

    2009-09-01

    Ultrafast electronic switches fabricated from defective material have been used for several decades in order to produce picosecond electrical transients and TeraHertz radiation. Due to the ultrashort recombination time in the photoconductor materials used, these switches are inefficient and are ultimately limited by the amount of optical power that can be applied to the switch before self-destruction. The goal of this work is to create ultrafast (sub-picosecond response) photoconductive switches on GaAs that are enhanced through plasmonic coupling structures. Here, the plasmonic coupler primarily plays the role of being a radiation condenser which will cause carriers to be generated adjacent to metallic electrodes where they can more efficiently be collected.

  1. An optical switch

    DOEpatents

    Christophorou, L.G.; Hunter, S.R.

    1987-04-30

    The invention is a gas mixture for a diffuse discharge switch having an electron attaching gas wherein electron attachment is brought about by indirect excitation of molecules to long live states by exposure to laser light. 3 figs.

  2. Switching and stopping antidepressants

    PubMed Central

    Keks, Nicholas; Hope, Judy; Keogh, Simone

    2016-01-01

    SUMMARY Switching from one antidepressant to another is frequently indicated due to an inadequate treatment response or unacceptable adverse effects. All antidepressant switches must be carried out cautiously and under close observation. Conservative switching strategies involve gradually tapering the first antidepressant followed by an adequate washout period before the new antidepressant is started. This can take a long time and include periods of no treatment with the risk of potentially life-threatening exacerbations of illness. Clinical expertise is needed for more rapid or cross-taper switching as drug toxicity, including serotonin syndrome, may result from inappropriate co-administration of antidepressants. Some antidepressants must not be combined. Antidepressants can cause withdrawal syndromes if discontinued abruptly after prolonged use. Relapse and exacerbation of depression can also occur. Gradual dose reduction over days to weeks reduces the risk and severity of complications. PMID:27346915

  3. Optical fiber crossbar switch

    NASA Astrophysics Data System (ADS)

    Kilcoyne, Michael K.; Beccue, Stephen M.; Brar, Berinder; Robinson, G.; Pedrotti, Kenneth D.; Haber, William A.

    1990-07-01

    Advances in high performance computers and signal processing systems have led to parallel system architectures. The main limitation in achieving the performance expected of these parallel systems has been the realization of an efficient means to interconnect many processors into a effective parallel system. Electronic interconnections have proved cumbersome, costly and ineffective. The Optical Fiber Crossbar Switch (OFCS) is a compact low power, multi-gigahertz bandwidth multi-channel switch which can be used in large scale computer and telecommunication applications. The switch operates in the optical domain using GaAs semiconductor lasers to transmit wideband multiple channel optical data over fiber optic cables. Recently, a 32 X 32 crossbar switching system was completed and demonstrated. Error free performance was obtained at a data bandwidth of 410 MBPS, using a silicon switch IC. The switch can be completely reconfigured in less than 50 nanoseconds under computer control. The fully populated OFCS has the capability to handle 12.8 gigabits per second (GBPS) of data while switching this data over 32 channels without the loss of a single bit during switching. GaAs IC technology has now progressed to the point that 16 X 16 GaAs based crossbar switch Ics are available which have increased the data bandwidth capability to 2.4 GBPS. The present optical interfaces are integrated GaAs transmitter drivers, GaAs lasers, and integrated GaAs optical receivers with data bandwidths exceeding 2.4 GBPS. A system using all Ill-V switching and optoelectronic components is presently under development for both NASA and DoD programs. The overall system is designed to operate at 1.3 GBPS. It is expected that these systems will find wide application in high capacity computing systems based on parallel microprocessor architecture which require high data bandwidth communication between processors. The OFCS will also have application in commercial optical telecommunication systems

  4. Cygnus PFL Switch Jitter

    SciTech Connect

    C. Mitton, G. Corrow, M. Hansen, D. Henderson, et al.

    2007-07-21

    The Cygnus Dual Beam Radiographic Facility consists of two identical radiographic sources: Cygnus 1 and Cygnus 2. Each source has the following X-ray output: 1-mm diameter spot size, 4 rads at 1 m, 50-ns full-widthhalf-maximum. The diode pulse has the following electrical specifications: 2.25 MV, 60 kA, 60 ns. This Radiographic Facility is located in an underground tunnel test area at the Nevada Test Site (NTS). The sources were developed to produce high-resolution images on subcritical tests performed at NTS. Subcritical tests are single-shot, high-value events. For this application, it is desirable to maintain a high level of reproducibility in source output. The major components of the Cygnus machines are Marx generator, water-filled pulse forming line (PFL), water-filled coaxial transmission line, threecell inductive voltage adder, and rod-pinch diode. A primary source of fluctuation in Cygnus shot-to-shot performance may be jitter in breakdown of the main PFL switch, which is a “self-break” switch. The PFL switch breakdown time determines the peak PFL charging voltage, which ultimately affects the source X-ray spectrum and dose. Therefore, PFL switch jitter may contribute to shot-to-shot variation in these parameters, which are crucial to radiographic quality. In this paper we will present PFL switch jitter analysis for both Cygnus machines and present the correlation with dose. For this analysis, the PFL switch on each machine was maintained at a single gap setting, which has been used for the majority of shots at NTS. In addition the PFL switch performance for one larger switch gap setting will be examined.

  5. High Power Switching Transistor

    NASA Technical Reports Server (NTRS)

    Hower, P. L.; Kao, Y. C.; Carnahan, D. C.

    1983-01-01

    Improved switching transistors handle 400-A peak currents and up to 1,200 V. Using large diameter silicon wafers with twice effective area as D60T, form basis for D7 family of power switching transistors. Package includes npn wafer, emitter preform, and base-contact insert. Applications are: 25to 50-kilowatt high-frequency dc/dc inverters, VSCF converters, and motor controllers for electrical vehicles.

  6. Cygnus Water Switch Jitter

    SciTech Connect

    Charles V. Mitton, George D. Corrow, Mark D. Hansen, David J. Henderson, et al.

    2008-03-01

    The Cygnus Dual Beam Radiographic Facility consists of two identical radiographic sources - Cygnus 1 and Cygnus 2. Each source has the following x-ray output: 1-mm diameter spot size, 4 rad at 1 m, 50-ns Full Width Half Max. The diode pulse has the following electrical specifications: 2.25 MV, 60 kA, 60 ns. This Radiographic Facility is located in an underground tunnel test area at the Nevada Test Site (NTS). The sources were developed to produce high-resolution images on subcritical tests which are performed at NTS. Subcritical tests are single-shot, high-value events. For this application, it is desirable to maintain a high level of reproducibility in source output. The major components of the Cygnus machines are: Marx generator, water-filled pulse–forming line (PFL), water-filled coaxial transmission line, three-cell inductive voltage adder, and rod-pinch diode. A primary source of fluctuation in Cygnus shot-to-shot performance is jitter in breakdown of the main PFL switch, which is a “self-break” switch. The PFL switch breakdown time determines the peak PFL charging voltage, which ultimately affects the diode pulse. Therefore, PFL switch jitter contributes to shot-to-shot variation in source endpoint energy and dose. In this paper we will present PFL switch jitter analysis for both Cygnus machines and give the correlation with diode performance. For this analysis the PFL switch on each machine was maintained at a single gap setting which has been used for the majority of shots at NTS. In addition to this analysis, PFL switch performance for different switch gap settings taken recently will be examined. Lastly, implications of source jitter for radiographic diagnosis of subcritical shots will be discussed.

  7. Finding a stabilising switching law for switching nonlinear models

    NASA Astrophysics Data System (ADS)

    Lendek, Zs.; Raica, P.; Lauber, J.; Guerra, T. M.

    2016-09-01

    This paper considers the stabilisation of switching nonlinear models by switching between the subsystems. We assume that arbitrary switching between two subsystems is possible once a subsystem has been active for a predefined number of samples. We use a Takagi-Sugeno representation of the models and a switching Lyapunov function is employed to develop sufficient stability conditions. If the conditions are satisfied, we construct a switching law that stabilises the system. The application of the conditions is illustrated in several examples.

  8. Low inductance gas switching.

    SciTech Connect

    Chavez, Ray; Harjes, Henry Charles III; Wallace, Zachariah; Elizondo, Juan E.

    2007-10-01

    The laser trigger switch (LTS) is a key component in ZR-type pulsed power systems. In ZR, the pulse rise time through the LTS is > 200 ns and additional stages of pulse compression are required to achieve the desired <100 ns rise time. The inductance of the LTS ({approx}500nH) in large part determines the energy transfer time through the switch and there is much to be gained in improving system performance and reducing system costs by reducing this inductance. The current path through the cascade section of the ZR LTS is at a diameter of {approx} 6-inches which is certainly not optimal from an inductance point of view. The LTS connects components of much greater diameter (typically 4-5 feet). In this LDRD the viability of switch concepts in which the diameter of cascade section is greatly increased have been investigated. The key technical question to be answered was, will the desired multi-channel behavior be maintained in a cascade section of larger diameter. This LDRD proceeded in 2 distinct phases. The original plan for the LDRD was to develop a promising switch concept and then design, build, and test a moderate scale switch which would demonstrate the key features of the concept. In phase I, a switch concept which meet all electrical design criteria and had a calculated inductance of 150 nH was developed. A 1.5 MV test switch was designed and fabrication was initiated. The LDRD was then redirected due to budgetary concerns. The fabrication of the switch was halted and the focus of the LDRD was shifted to small scale experiments designed to answer the key technical question concerning multi-channel behavior. In phase II, the Multi-channel switch test bed (MCST) was designed and constructed. The purpose of MCST was to provide a versatile, fast turn around facility for the study the multi-channel electrical breakdown behavior of a ZR type cascade switch gap in a parameter space near that of a ZR LTS. Parameter scans on source impedance, gap tilt, gap spacing and

  9. Innovative switching technology

    NASA Astrophysics Data System (ADS)

    Rosen, A.; Stabile, P. J.; Gombar, A. M.; Janton, W. M.; Gilbert, D. B.; Herczfeld, P. R.; Bahasadri, A.

    1991-03-01

    We have developed an all-semiconductor high-power optical switch. Potential uses include both military applications, such as ultra-wide-band impulse radar and high-frequency antenna couplers, and commercial use, such as high-power switching for utility companies. Under this three-year program, we have demonstrated various switching applications from dc to GHz frequencies. The generic switches comprise a 2-D semiconductor laser diode array and Si or GaAs devices. In the Si area (linear switches - no gain) and dc-biased network, a single two-sided PIN device, activated by two 1 kW laser arrays, has yielded a holding voltage of 1.3 kV and conducted 192 A. Similar devices have later yielded a holding voltage of 3.3 kV, demonstrating the capability of switching more than 500 kW with a single two-sided PIN device. The same generic technology was also demonstrated in high-power high-frequency antenna coupler applications as well as in mm-wave (60 GHz) attenuators and phase shifters. PIN devices tested in a RF circuit between 2-30 MHz yielded an isolation value of between 28 and 49 dB in the off-state, and insertion losses as low as 0.1 dB when illuminated with 280 W (peak) optical power at 808 nm. In the area of GaAs, PIN, and bulk devices under this project, we were able to deliver devices for experiments in both opening and closing switches. We have demonstrated a compact, all-semiconductor switch system that has switched up to 8.5 MW into a 38 (omega) load. The system uses a 2-D laser diode array with a peak power of 850 W to rigger a 1.5 cm long GaAs photoconductor into a high-gain combination mode known as 'lock on'. The highest power switch was pulse-charged to 55 kV and delivered 470 A to a 38 (omega) load in 160 ns long pulse. In the area of 2-D laser arrays, a peak power density of 7 kW/cm(exp 2) was achieved.

  10. Long Life MEM Switch Technology

    DTIC Science & Technology

    2006-05-23

    The first type of MEM switch developed was the miniature switched capacitor. This device is 150-300 times smaller than conventional MEM switches...down and the shunt capacitance to the ground is increased. The mechanical behavior of the MEM capacitor is designed using conventional mechanical...switched capacitors. It proves that by decreasing the size, miniature switched capacitors with Con/ Coff =2.8 for a single bridge and Con/ Coff =1.9 for a 3

  11. Switching power pulse system

    DOEpatents

    Aaland, K.

    1983-08-09

    A switching system for delivering pulses of power from a source to a load using a storage capacitor charged through a rectifier, and maintained charged to a reference voltage level by a transistor switch and voltage comparator. A thyristor is triggered to discharge the storage capacitor through a saturable reactor and fractional turn saturable transformer having a secondary to primary turn ratio N of n:l/n = n[sup 2]. The saturable reactor functions as a soaker'' while the thyristor reaches saturation, and then switches to a low impedance state. The saturable transformer functions as a switching transformer with high impedance while a load coupling capacitor charges, and then switches to a low impedance state to dump the charge of the storage capacitor into the load through the coupling capacitor. The transformer is comprised of a multilayer core having two secondary windings tightly wound and connected in parallel to add their output voltage and reduce output inductance, and a number of single turn windings connected in parallel at nodes for the primary winding, each single turn winding linking a different one of the layers of the multilayer core. The load may be comprised of a resistive beampipe for a linear particle accelerator and capacitance of a pulse forming network. To hold off discharge of the capacitance until it is fully charged, a saturable core is provided around the resistive beampipe to isolate the beampipe from the capacitance until it is fully charged. 5 figs.

  12. Atomic Scale Plasmonic Switch.

    PubMed

    Emboras, Alexandros; Niegemann, Jens; Ma, Ping; Haffner, Christian; Pedersen, Andreas; Luisier, Mathieu; Hafner, Christian; Schimmel, Thomas; Leuthold, Juerg

    2016-01-13

    The atom sets an ultimate scaling limit to Moore's law in the electronics industry. While electronics research already explores atomic scales devices, photonics research still deals with devices at the micrometer scale. Here we demonstrate that photonic scaling, similar to electronics, is only limited by the atom. More precisely, we introduce an electrically controlled plasmonic switch operating at the atomic scale. The switch allows for fast and reproducible switching by means of the relocation of an individual or, at most, a few atoms in a plasmonic cavity. Depending on the location of the atom either of two distinct plasmonic cavity resonance states are supported. Experimental results show reversible digital optical switching with an extinction ratio of 9.2 dB and operation at room temperature up to MHz with femtojoule (fJ) power consumption for a single switch operation. This demonstration of an integrated quantum device allowing to control photons at the atomic level opens intriguing perspectives for a fully integrated and highly scalable chip platform, a platform where optics, electronics, and memory may be controlled at the single-atom level.

  13. Silicon carbide photoconductive switches

    NASA Astrophysics Data System (ADS)

    Saddow, Stephen E.

    1994-09-01

    The optoelectronic properties of p-type 6-H silicon carbide (6H-SiC) have been investigated in an experiment that used lateral and vertical photoconductive (PC) switches. Both photovoltaic and photoconductive effects are reported, which were observed on switches using both geometries and measured at several wavelengths near the 6H-SiC absorption edge. PC techniques were employed to measure the surface and bulk carrier lifetimes of 40 and 200 ns, respectively. The switches displayed a high-speed photovoltaic response to picosecond laser excitations in the UV and visible spectral regions. In particular, efficient subnanosecond optical absorption processes were observed in the visible region. The photovoltage was measured as a function of both laser wavelength (and hence absorption depth) and laser beam position within the switching gap. The switch response to picosecond laser pulses in the UV, violet, green, and red spectral regions was shown to have subnanosecond photovoltaic response times. Finally, since the optical absorption coefficient had not been well established for device-grade 6H-SiC, the optical absorption coefficient near the 6H-SiC bandgap energy (Eg) was also measured, and the bandgap was determined to be approximately 3.1 eV.

  14. Multiple switch actuator

    DOEpatents

    Beyer, Edward T.

    1976-01-06

    The present invention relates to switches and switch actuating devices to be operated for purposes of arming a bomb or other missile as it is dropped or released from an aircraft. The particular bomb or missile in which this invention is applied is one in which there is a plurality of circuits which are to be armed by the closing of switches upon dropping or releasing of the bomb. The operation of the switches to closed position is normally accomplished by means of a pull-out wire; that is, a wire which is withdrawn from the bomb or missile at the time of release of the bomb, one end of the wire being attached to the aircraft. The conditions to be met are that the arming switches must be positively and surely maintained in open position until the bomb is released and the arming action is effected. The action of the pull-out wire in achieving the arming action must be sure and positive with minimum danger of malfunctioning, jamming or binding.

  15. Thermionic gas switch

    DOEpatents

    Hatch, G.L.; Brummond, W.A.; Barrus, D.M.

    1984-04-05

    The present invention is directed to an improved temperature responsive thermionic gas switch utilizing a hollow cathode and a folded emitter surface area. The folded emitter surface area of the thermionic switch substantially increases the on/off ratio by changing the conduction surface area involved in the two modes thereof. The improved switch of this invention provides an on/off ratio of 450:1 compared to the 10:1 ratio of the prior known thermionic switch, while providing for adjusting the on current. In the improved switch of this invention the conduction area is made small in the off mode, while in the on mode the conduction area is made large. This is achieved by utilizing a folded hollow cathode configuration and utilizing a folded emitter surface area, and by making the dimensions of the folds small enough so that a space charge will develop in the convolutions of the folds and suppress unignited current, thus limiting the current carrying surface in the off mode.

  16. Microfabricated triggered vacuum switch

    DOEpatents

    Roesler, Alexander W.; Schare, Joshua M.; Bunch, Kyle

    2010-05-11

    A microfabricated vacuum switch is disclosed which includes a substrate upon which an anode, cathode and trigger electrode are located. A cover is sealed over the substrate under vacuum to complete the vacuum switch. In some embodiments of the present invention, a metal cover can be used in place of the trigger electrode on the substrate. Materials used for the vacuum switch are compatible with high vacuum, relatively high temperature processing. These materials include molybdenum, niobium, copper, tungsten, aluminum and alloys thereof for the anode and cathode. Carbon in the form of graphitic carbon, a diamond-like material, or carbon nanotubes can be used in the trigger electrode. Channels can be optionally formed in the substrate to mitigate against surface breakdown.

  17. Optical computer switching network

    NASA Technical Reports Server (NTRS)

    Clymer, B.; Collins, S. A., Jr.

    1985-01-01

    The design for an optical switching system for minicomputers that uses an optical spatial light modulator such as a Hughes liquid crystal light valve is presented. The switching system is designed to connect 80 minicomputers coupled to the switching system by optical fibers. The system has two major parts: the connection system that connects the data lines by which the computers communicate via a two-dimensional optical matrix array and the control system that controls which computers are connected. The basic system, the matrix-based connecting system, and some of the optical components to be used are described. Finally, the details of the control system are given and illustrated with a discussion of timing.

  18. Switching power supply

    DOEpatents

    Mihalka, A.M.

    1984-06-05

    The invention is a repratable capacitor charging, switching power supply. A ferrite transformer steps up a dc input. The transformer primary is in a full bridge configuration utilizing power MOSFETs as the bridge switches. The transformer secondary is fed into a high voltage, full wave rectifier whose output is connected directly to the energy storage capacitor. The transformer is designed to provide adequate leakage inductance to limit capacitor current. The MOSFETs are switched to the variable frequency from 20 to 50 kHz to charge a capacitor from 0.6 kV. The peak current in a transformer primary and secondary is controlled by increasing the pulse width as the capacitor charges. A digital ripple counter counts pulses and after a preselected desired number is reached an up-counter is clocked.

  19. SWITCH user's manual

    NASA Technical Reports Server (NTRS)

    1987-01-01

    The planning program, SWITCH, and its surrounding changed-goal-replanning program, Runaround, are described. The evolution of SWITCH and Runaround from an earlier planner, DEVISER, is recounted. SWITCH's plan representation, and its process of building a plan by backward chaining with strict chronological backtracking, are described. A guide for writing knowledge base files is provided, as are narrative guides for installing the program, running it, and interacting with it while it is running. Some utility functions are documented. For the sake of completeness, a narrative guide to the experimental discrepancy-replanning feature is provided. Appendices contain knowledge base files for a blocksworld domain, and a DRIBBLE file illustrating the output from, and user interaction with, the program in that domain.

  20. Optical Computer Switching Network

    NASA Astrophysics Data System (ADS)

    Clymer, B.; Collins, S. A., Jr.

    1985-02-01

    In this paper we present the design for an optical switching system for minicomputers that uses an optical spatial light modulator such as a Hughes liquid crystal light valve. The switching system is designed to connect 80 minicomputers coupled to the switching system by optical fibers. The system has two major parts: the connection system that connects the data lines by which the computers communicate via a two-dimensional optical matrix array and the control system that controls which computers are connected. We first present the basic system, then describe the matrix-based connecting system and review some of the optical components to be used. Finally, the details of the control system are given and illustrated with a discussion of timing.

  1. Optical computer switching network

    NASA Astrophysics Data System (ADS)

    Clymer, B.; Collins, S. A., Jr.

    1985-02-01

    The design for an optical switching system for minicomputers that uses an optical spatial light modulator such as a Hughes liquid crystal light valve is presented. The switching system is designed to connect 80 minicomputers coupled to the switching system by optical fibers. The system has two major parts: the connection system that connects the data lines by which the computers communicate via a two-dimensional optical matrix array and the control system that controls which computers are connected. The basic system, the matrix-based connecting system, and some of the optical components to be used are described. Finally, the details of the control system are given and illustrated with a discussion of timing.

  2. Optical computer switching network

    NASA Technical Reports Server (NTRS)

    Clymer, B.; Collins, S. A., Jr.

    1985-01-01

    The design for an optical switching system for minicomputers that uses an optical spatial light modulator such as a Hughes liquid crystal light valve is presented. The switching system is designed to connect 80 minicomputers coupled to the switching system by optical fibers. The system has two major parts: the connection system that connects the data lines by which the computers communicate via a two-dimensional optical matrix array and the control system that controls which computers are connected. The basic system, the matrix-based connecting system, and some of the optical components to be used are described. Finally, the details of the control system are given and illustrated with a discussion of timing.

  3. SHOCKPROOF MAGNETIC REED SWITCH

    DOEpatents

    Medal, E.

    1962-03-13

    A shockproof magnetic reed switch is described which comprises essentially a plurality of pairs of reed contacts of magnetic, electrical conducting material which are arranged generally in circumferential spaced relationship. At least two of the pairs are disposed to operate at a predetermined angle with respect to each other, and the contacts are wired in the circuit, so that the continuity, or discontinuity, of the circuit is not affected by a shock imposed on the switch. The contacts are hermetically sealed within an outer tubular jacket. (AEC)

  4. Thermionic gas switch

    DOEpatents

    Hatch, George L.; Brummond, William A.; Barrus, Donald M.

    1986-01-01

    A temperature responsive thermionic gas switch having folded electron emitting surfaces. An ionizable gas is located between the emitter and an interior surface of a collector, coaxial with the emitter. In response to the temperature exceeding a predetermined level, sufficient electrons are derived from the emitter to cause the gas in the gap between the emitter and collector to become ionized, whereby a very large increase in current in the gap occurs. Due to the folded emitter surface area of the switch, increasing the "on/off" current ratio and adjusting the "on" current capacity is accomplished.

  5. Organometallic spintronics: dicobaltocene switch.

    PubMed

    Liu, Rui; Ke, San-Huang; Baranger, Harold U; Yang, Weitao

    2005-10-01

    A single-molecule spintronic switch and spin valve using two cobaltocene moieties is proposed. Spin-dependent transport through a lead-molecule-lead junction has been calculated using first-principles density functional and nonequilibrium Green function methods. We find that the antiparallel (singlet) configuration of the cobaltocene spins blocks electron transport near the Fermi energy, while the spin parallel (triplet) configuration enables much higher current. The energy difierence between the antiparallel and parallel states depends on the insulating spacer separating the two cobaltocenes, allowing switching through the application of a moderate magnetic field.

  6. Optimizing pump-probe switching ruled by free-carrier dispersion.

    PubMed

    Malaguti, S; Bellanca, G; Trillo, S

    2013-07-01

    We address theoretically and numerically pump-probe switching in a nonlinear semiconductor nanocavity where tuning is achieved via a dominant mechanism of free-carrier plasma dispersion. By using coupled-mode approach we give a set of guidelines to optimize the switching performances both in terms of avoiding self-pulsation and keeping switching power to the minimum, ending up by showing that such devices can achieve high-performances with relatively low-power consumption.

  7. Main electrical switch banks, plant switch house, looking to the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Main electrical switch banks, plant switch house, looking to the North - Bureau of Mines Metallurgical Research Laboratory, Original Building, Date Street north of U.S. Highway 93, Boulder City, Clark County, NV

  8. Hybrid solid state switch replaces motor- driven power switch

    NASA Technical Reports Server (NTRS)

    Booth, R. A.; Schloss, A. I.

    1967-01-01

    Hybrid solid state switch replaces existing motor-driven power switches used on spacecraft. It uses a transistor circuit to limit the open circuit voltage and allow small relay contacts to handle high transient currents at reasonable cycle life.

  9. 41. INTERIOR VIEW, GREEN SWITCH TOWER, COS COB, SHOWING SWITCH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    41. INTERIOR VIEW, GREEN SWITCH TOWER, COS COB, SHOWING SWITCH LEVER ASSEMBLAGE AND DISPLAY BOARD - New York, New Haven & Hartford Railroad, Automatic Signalization System, Long Island Sound shoreline between Stamford & New Haven, Stamford, Fairfield County, CT

  10. 35. END VIEW, INTERIOR, SHOWING SWITCHING LEVERS, BERK SWITCH TOWER, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    35. END VIEW, INTERIOR, SHOWING SWITCHING LEVERS, BERK SWITCH TOWER, SOUTH NORWALK - New York, New Haven & Hartford Railroad, Automatic Signalization System, Long Island Sound shoreline between Stamford & New Haven, Stamford, Fairfield County, CT

  11. 36. INTERIOR VIEW, BERK SWITCH TOWER, SOUTH NORWALK, SHOWING SWITCHING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    36. INTERIOR VIEW, BERK SWITCH TOWER, SOUTH NORWALK, SHOWING SWITCHING LEVERS FROM OPERATOR'S POSITION - New York, New Haven & Hartford Railroad, Automatic Signalization System, Long Island Sound shoreline between Stamford & New Haven, Stamford, Fairfield County, CT

  12. 43. OBLIQUE VIEW, GREEN SWITCH TOWER, COS COB, SHOWING SWITCH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    43. OBLIQUE VIEW, GREEN SWITCH TOWER, COS COB, SHOWING SWITCH LEVER ASSEMBLAGE AND DISPLAY BOARD - New York, New Haven & Hartford Railroad, Automatic Signalization System, Long Island Sound shoreline between Stamford & New Haven, Stamford, Fairfield County, CT

  13. Photonic MEMS switch applications

    NASA Astrophysics Data System (ADS)

    Husain, Anis

    2001-07-01

    As carriers and service providers continue their quest for profitable network solutions, they have shifted their focus from raw bandwidth to rapid provisioning, delivery and management of revenue generating services. Inherently transparent to data rate the transmission wavelength and data format, MEMS add scalability, reliability, low power and compact size providing flexible solutions to the management and/or fiber channels in long haul, metro, and access networks. MEMS based photonic switches have gone from the lab to commercial availability and are now currently in carrier trials and volume production. 2D MEMS switches offer low up-front deployment costs while remaining scalable to large arrays. They allow for transparent, native protocol transmission. 2D switches enable rapid service turn-up and management for many existing and emerging revenue rich services such as storage connectivity, optical Ethernet, wavelength leasing and optical VPN. As the network services evolve, the larger 3D MEMS switches, which provide greater scalability and flexibility, will become economically viable to serve the ever-increasing needs.

  14. Kiowa Creek Switching Station

    SciTech Connect

    Not Available

    1990-03-01

    The Western Area Power Administration (Western) proposes to construct, operate, and maintain a new Kiowa Creek Switching Station near Orchard in Morgan County, Colorado. Kiowa Creek Switching Station would consist of a fenced area of approximately 300 by 300 feet and contain various electrical equipment typical for a switching station. As part of this new construction, approximately one mile of an existing 115-kilovolt (kV) transmission line will be removed and replaced with a double circuit overhead line. The project will also include a short (one-third mile) realignment of an existing line to permit connection with the new switching station. In accordance with the Council on Environmental Quality (CEQ) regulations for implementing the procedural provisions of the National Environmental Policy Act of 1969 (NEPA), 40 CFR Parts 1500--1508, the Department of Energy (DOE) has determined that an environmental impact statement (EIS) is not required for the proposed project. This determination is based on the information contained in this environmental assessment (EA) prepared by Western. The EA identifies and evaluates the environmental and socioeconomic effects of the proposed action, and concludes that the advance impacts on the human environment resulting from the proposed project would not be significant. 8 refs., 3 figs., 1 tab.

  15. Multipath star switch controller

    NASA Technical Reports Server (NTRS)

    Anderson, T. O.

    1980-01-01

    Device concept permits parallel computers to scan several commonnetwork-connected data stations at maximum rate. Sequencers leap-frog to bypass ports already being serviced by another computer. Two-path system for 16-port star switch controller is cost effective if added bandwidth or increased reliability is desired. Triple-path system would be cost effective for 32-port controller.

  16. Waveguide switch protector

    NASA Technical Reports Server (NTRS)

    Kolbly, R. B.

    1972-01-01

    Device for detecting excessive operation of electric motors used to drive waveguide switches is described. Purpose of device is to prevent burnout of electric motor in event of waveguide stoppage at some point other than extreme limits of travel. Operation of equipment, components used to sense motor performance, and schematic diagram are included.

  17. Gas injected vacuum switch

    DOEpatents

    Hardin, K. Dan

    1977-01-01

    The disclosure relates to a gas injected vacuum switch comprising a housing having an interior chamber, a conduit for evacuating the interior chamber, within the chamber an anode and a cathode spaced from the anode, and a detonator for injecting electrically conductive gas into the chamber between the anode and the cathode to provide a current path therebetween.

  18. Silicon Carbide Photoconductive Switches

    DTIC Science & Technology

    1994-09-01

    The optoelectronic properties of p-type 6-H silicon carbide (6H-SiC) have been investigated in an experiment that used lateral and vertical...and the bandgap was determined to be approximately 3.1 eV. 6H-SiC, Photoconductive, Photovoltaic, Absorption coefficient, Switch, Silicon carbide

  19. An integrated circuit switch

    NASA Technical Reports Server (NTRS)

    Bonin, E. L.

    1969-01-01

    Multi-chip integrated circuit switch consists of a GaAs photon-emitting diode in close proximity with S1 phototransistor. A high current gain is obtained when the transistor has a high forward common-emitter current gain.

  20. Molecular Rotors as Switches

    PubMed Central

    Xue, Mei; Wang, Kang L.

    2012-01-01

    The use of a functional molecular unit acting as a state variable provides an attractive alternative for the next generations of nanoscale electronics. It may help overcome the limits of conventional MOSFETd due to their potential scalability, low-cost, low variability, and highly integratable characteristics as well as the capability to exploit bottom-up self-assembly processes. This bottom-up construction and the operation of nanoscale machines/devices, in which the molecular motion can be controlled to perform functions, have been studied for their functionalities. Being triggered by external stimuli such as light, electricity or chemical reagents, these devices have shown various functions including those of diodes, rectifiers, memories, resonant tunnel junctions and single settable molecular switches that can be electronically configured for logic gates. Molecule-specific electronic switching has also been reported for several of these device structures, including nanopores containing oligo(phenylene ethynylene) monolayers, and planar junctions incorporating rotaxane and catenane monolayers for the construction and operation of complex molecular machines. A specific electrically driven surface mounted molecular rotor is described in detail in this review. The rotor is comprised of a monolayer of redox-active ligated copper compounds sandwiched between a gold electrode and a highly-doped P+ Si. This electrically driven sandwich-type monolayer molecular rotor device showed an on/off ratio of approximately 104, a read window of about 2.5 V, and a retention time of greater than 104 s. The rotation speed of this type of molecular rotor has been reported to be in the picosecond timescale, which provides a potential of high switching speed applications. Current-voltage spectroscopy (I-V) revealed a temperature-dependent negative differential resistance (NDR) associated with the device. The analysis of the device I–V characteristics suggests the source of the

  1. Exhaust Fan Temperature Switch

    SciTech Connect

    Ball, G.S.; /Fermilab

    1989-05-11

    The 13000 cfm 'emergency' vent fan must be protected from over cooling which would result in a mechanical failure. Over cooling could result from a catastrophic cryogen release from the cryostat(s) or Argon Storage Dewar. In order to protect the fan, a VPT has been calibrated for -31 C to open a switch which sends a signal to allow warm gas to enter the sump by means of a motor controlled louver installed at 'sidewalk level' in the ductwork between the assembly hall and the Argon Dewar Enclosure. The bulb of the VPT is enclosed in a thermal well and will be placed in the gas stream directly above the fan. The switching unit will be mounted nearby on the wall in order to isolate it from vibrational effects. Should the fan be activated due to a cryogen release, it should not experience any problems when operating above -40 C. The switch was set and checked in a saturated calcium chloride solution cooled to -31 C by running cold gaseous Nitrogen through a copper tube coiled in a dewar. Switching temperature was measured by a thermocouple tied to the VPT bulb. The thermocouple was checked in LN2, in an ice water bath, and against an ordinary thermometer (which was assumed to be accurate to plus or minus 0.3 C) at room temperature. The results are shown below in 'Table 1' By interpolation of the data, thermocouple error at -31.0 C was found to be 0.43 C on the warm side. Since this error was small, it was ignored. 'Table 2' shows the results of the tests. Ten readings were taken with the switch wired in the 'normally open' mode. This results in a signal at room temperature. The worst deviation was 2.5 C. Three readings were then taken from the 'normally closed' wiring arrangement (the way it will be wired for installation). The greatest deviation was 1.2 C. The next day, the switch was checked five times wired in the 'normally open' configuration. The greatest error was 1.1 C. A graph has been prepared showing the switching and resetting temperatures. The errors these

  2. Heat-transfer thermal switch

    NASA Technical Reports Server (NTRS)

    Friedell, M. V.; Anderson, A. J.

    1974-01-01

    Thermal switch maintains temperature of planetary lander, within definite range, by transferring heat. Switch produces relatively large stroke and force, uses minimum electrical power, is lightweight, is vapor pressure actuated, and withstands sterilization temperatures without damage.

  3. Automatic thermal switch. [spacecraft applications

    NASA Technical Reports Server (NTRS)

    Cunningham, J. W.; Wing, L. D. (Inventor)

    1983-01-01

    An automatic thermal switch to control heat flow includes two thermally conductive plates and a thermally conductive switch saddle pivotally mounted to the first plate. A flexible heat carrier is connected between the switch saddle and the second plate. A phase-change power unit, including a piston coupled to the switch saddle, is in thermal contact with the first thermally conductive plate. A biasing element biases the switch saddle in a predetermined position with respect to the first plate. When the phase-change power unit is actuated by an increase in heat transmitted through the first place, the piston extends and causes the switch saddle to pivot, thereby varying the thermal conduction between the two plates through the switch saddle and flexible heat carrier. The biasing element, switch saddle, and piston can be arranged to provide either a normally closed or normally opened thermally conductive path between the two plates.

  4. Switching power pulse system

    DOEpatents

    Aaland, Kristian

    1983-01-01

    A switching system for delivering pulses of power from a source (10) to a load (20) using a storage capacitor (C3) charged through a rectifier (D1, D2), and maintained charged to a reference voltage level by a transistor switch (Q1) and voltage comparator (12). A thyristor (22) is triggered to discharge the storage capacitor through a saturable reactor (18) and fractional turn saturable transformer (16) having a secondary to primary turn ratio N of n:l/n=n.sup.2. The saturable reactor (18) functions as a "soaker" while the thyristor reaches saturation, and then switches to a low impedance state. The saturable transformer functions as a switching transformer with high impedance while a load coupling capacitor (C4) charges, and then switches to a low impedance state to dump the charge of the storage capacitor (C3) into the load through the coupling capacitor (C4). The transformer is comprised of a multilayer core (26) having two secondary windings (28, 30) tightly wound and connected in parallel to add their output voltage and reduce output inductance, and a number of single turn windings connected in parallel at nodes (32, 34) for the primary winding, each single turn winding linking a different one of the layers of the multilayer core. The load may be comprised of a resistive beampipe (40) for a linear particle accelerator and capacitance of a pulse forming network (42). To hold off discharge of the capacitance until it is fully charged, a saturable core (44) is provided around the resistive beampipe (40) to isolate the beampipe from the capacitance (42) until it is fully charged.

  5. Operation of a homeostatic sleep switch.

    PubMed

    Pimentel, Diogo; Donlea, Jeffrey M; Talbot, Clifford B; Song, Seoho M; Thurston, Alexander J F; Miesenböck, Gero

    2016-08-18

    Sleep disconnects animals from the external world, at considerable risks and costs that must be offset by a vital benefit. Insight into this mysterious benefit will come from understanding sleep homeostasis: to monitor sleep need, an internal bookkeeper must track physiological changes that are linked to the core function of sleep. In Drosophila, a crucial component of the machinery for sleep homeostasis is a cluster of neurons innervating the dorsal fan-shaped body (dFB) of the central complex. Artificial activation of these cells induces sleep, whereas reductions in excitability cause insomnia. dFB neurons in sleep-deprived flies tend to be electrically active, with high input resistances and long membrane time constants, while neurons in rested flies tend to be electrically silent. Correlative evidence thus supports the simple view that homeostatic sleep control works by switching sleep-promoting neurons between active and quiescent states. Here we demonstrate state switching by dFB neurons, identify dopamine as a neuromodulator that operates the switch, and delineate the switching mechanism. Arousing dopamine caused transient hyperpolarization of dFB neurons within tens of milliseconds and lasting excitability suppression within minutes. Both effects were transduced by Dop1R2 receptors and mediated by potassium conductances. The switch to electrical silence involved the downregulation of voltage-gated A-type currents carried by Shaker and Shab, and the upregulation of voltage-independent leak currents through a two-pore-domain potassium channel that we term Sandman. Sandman is encoded by the CG8713 gene and translocates to the plasma membrane in response to dopamine. dFB-restricted interference with the expression of Shaker or Sandman decreased or increased sleep, respectively, by slowing the repetitive discharge of dFB neurons in the ON state or blocking their entry into the OFF state. Biophysical changes in a small population of neurons are thus linked to the

  6. Transparent electrode for optical switch

    DOEpatents

    Goldhar, J.; Henesian, M.A.

    1984-10-19

    The invention relates generally to optical switches and techniques for applying a voltage to an electro-optical crystal, and more particularly, to transparent electodes for an optical switch. System architectures for very large inertial confinement fusion (ICF) lasers require active optical elements with apertures on the order of one meter. Large aperture optical switches are needed for isolation of stages, switch-out from regenerative amplifier cavities and protection from target retroreflections.

  7. Radiation sensitive solid state switch

    NASA Technical Reports Server (NTRS)

    Hutto, R. J. (Inventor)

    1973-01-01

    A mechanically operable solid state switch suited for use in achieving a variable circuit-switching function is described. This switch is characterized by an annular array of photoresponsive switching devices, disposed in communication with an included source of radiation, and a plurality of interchangeable, mechanically operable interrupter disks. Each disk has a predetermined pattern of transparent and opaque portions. Operative displacement of each disk serves to make and break selected electrical circuits through the photo responsive devices of said array.

  8. Easily-wired toggle switch

    NASA Technical Reports Server (NTRS)

    Dean, W. T.; Stringer, E. J.

    1979-01-01

    Crimp-type connectors reduce assembly and disassembly time. With design, no switch preparation is necessary and socket contracts are crimped to wires inserted in module attached to back of toggle switch engaging pins inside module to make electrical connections. Wires are easily removed with standard detachment tool. Design can accommodate wires of any gage and as many terminals can be placed on switch as wire gage and switch dimensions will allow.

  9. Illuminated push-button switch

    NASA Technical Reports Server (NTRS)

    Iwagiri, T.

    1983-01-01

    An illuminated push-button switch is described. It is characterized by the fact that is consists of a switch group, an operator button opening and closing the switch group, and a light-emitting element which illuminates the face of the operator button.

  10. Illuminated push-button switch

    NASA Astrophysics Data System (ADS)

    Iwagiri, T.

    1983-05-01

    An illuminated push-button switch is described. It is characterized by the fact that is consists of a switch group, an operator button opening and closing the switch group, and a light-emitting element which illuminates the face of the operator button.

  11. Organic Materials For Optical Switching

    NASA Technical Reports Server (NTRS)

    Cardelino, Beatriz H.

    1993-01-01

    Equations predict properties of candidate materials. Report presents results of theoretical study of nonlinear optical properties of organic materials. Such materials used in optical switching devices for computers and telecommunications, replacing electronic switches. Optical switching potentially offers extremely high information throughout in compact hardware.

  12. Design and performance of the beamlet optical switch

    SciTech Connect

    Rhodes, M.A.; Woods, B.W.; DeYoreo, J.J.

    1996-06-01

    High-energy lasers for Inertial Confinement Fusion (ICF) experiments are typically designed with large apertures (>30 cm) to keep the fluence below the damage threshold of the various optical components. Until recently, no optical switch technology could be scaled to the aperture size, aperture shape (square), and switching speed required for the next generation of ICF drivers. This step is critical: The Beamlet multipass amplifier cavity uses a full-aperture optical switch to trap the laser pulse within the cavity and to divert the pulse out of the cavity when it reaches the required energy. By rotating the polarization of the beam, a Pockels cell in the switch controls whether the beam is transmitted through, or reflected from, the polarizer. In this article the authors describe an optical switch technology that does scale to the required aperture size and shape for Beamlet and the porposed National Ignition Facility (NIF) laser, and can employ a thin crystal. This switch consists of a thin-film polarizer and a plasma-electrode Pockels cell (PEPC), the latter originally invented at Lawrence Livermore National Laboratory (LLNL) in the 1980s and under further development since 1991. After discussing the PEPC concept, they present the design and optical performance of a 32 x 32 cm{sup 2} prototype PEPC, including discussions of the crystals, the PEPC assembly, the vacuum and gas system, and the high-voltage pulsers. Then they describe the performance of the 37 x 37 cm{sup 2} PEPC construced specifically for the Beamlet laser. Finally, they discuss important technology issues that arose during PEPC development: cathode sputtering, cathode heating, nonuniformities in the switching profile, switch-pulse leakage current, and an estimate of the plasma density and temperature produced during PEPC operation.

  13. Energy efficiency of electron plasma emitters

    SciTech Connect

    Zalesski, V. G.

    2011-12-15

    Electron emission influence from gas-discharge plasma on plasma emitter energy parameters is considered. It is shown, that electron emission from plasma is accompanied by energy contribution redistribution in the gas-discharge from plasma emitter supplies sources-the gas-discharge power supply and the accelerating voltage power supply. Some modes of electron emission as a result can be realized: 'a probe measurements mode,' 'a transitive mode,' and 'a full switching mode.'.

  14. CMOS analog switches for adaptive filters

    NASA Technical Reports Server (NTRS)

    Dixon, C. E.

    1980-01-01

    Adaptive active low-pass filters incorporate CMOS (Complimentary Metal-Oxide Semiconductor) analog switches (such as 4066 switch) that reduce variation in switch resistance when filter is switched to any selected transfer function.

  15. High gain GaAs photoconductive semiconductor switches: Switch longevity

    SciTech Connect

    Loubriel, G.M.; Zutavern, F.J.; Mar, A.

    1998-07-01

    Optically activated, high gain GaAs switches are being tested for many different pulsed power applications that require long lifetime (longevity). The switches have p and n contact metallization (with intentional or unintentional dopants) configured in such a way as to produce p-i-n or n-i-n switches. The longevity of the switches is determined by circuit parameters and by the ability of the contacts to resist erosion. This paper will describe how the switches performed in test-beds designed to measure switch longevity. The best longevity was achieved with switches made with diffused contacts, achieving over 50 million pulses at 10 A and over 2 million pulses at 80 A.

  16. Basic Studies of Gases for Fast Switches.

    DTIC Science & Technology

    1985-01-01

    nanoseconds. The major technological problem to be faced when using this type of energy storage system is in the design of a repetitive opening switch. A...M. Vitkovitsky, IEEE Trans. Plasma Sci. PS-8, 176 (1980). 3. K. H. Schoenbach, G. Schaefer, E. E. Kunhardt, M. Kristiansen, L. L. Hatfield, and A. H...Kristianser. and Schoerbach. 1981). One of 󈧜 GovT @dMabje to DTIC does 6 wait tUjll legible repTOdU’O"’ L the major problems to be faced vith this

  17. Isolated Fast High-Voltage Switching Circuit

    NASA Technical Reports Server (NTRS)

    Rizzi, Anthony

    1992-01-01

    Electrically isolated switching circuit supplies pulses at potentials up to 6.5 kV and currents up to 6.5 A, lasting as long as few microseconds. Turn-on time about 40 ns; turn-off time about 3 microseconds. Electrically isolated from control circuitry by means of fiber-optic signal coupling and isolated power supply. Electrical isolation protects both technician and equipment. This and similar circuits useful in such industrial and scientific applications as high-voltage, high-frequency test equipment; electrostatic-discharge test equipment; plasma-laboratory instrumentation; spark chambers; and electromagnetic-interference test equipment.

  18. Fast Electromechanical Switches Based on Carbon Nanotubes

    NASA Technical Reports Server (NTRS)

    Kaul, Anupama; Wong, Eric; Epp, Larry

    2008-01-01

    Electrostatically actuated nanoelectromechanical switches based on carbon nanotubes have been fabricated and tested in a continuing effort to develop high-speed switches for a variety of stationary and portable electronic equipment. As explained below, these devices offer advantages over electrostatically actuated microelectromechanical switches, which, heretofore, have represented the state of the art of rapid, highly miniaturized electromechanical switches. Potential applications for these devices include computer memories, cellular telephones, communication networks, scientific instrumentation, and general radiation-hard electronic equipment. A representative device of the present type includes a single-wall carbon nanotube suspended over a trench about 130 nm wide and 20 nm deep in an electrically insulating material. The ends of the carbon nanotube are connected to metal electrodes, denoted the source and drain electrodes. At bottom of the trench is another metal electrode, denoted the pull electrode (see figure). In the off or open switch state, no voltage is applied, and the nanotube remains out of contact with the pull electrode. When a sufficiently large electric potential (switching potential) is applied between the pull electrode and either or both of the source and drain electrodes, the resulting electrostatic attraction bends and stretches the nanotube into contact with the pull electrode, thereby putting the switch into the "on" or "closed" state, in which substantial current (typically as much as hundreds of nanoamperes) is conducted. Devices of this type for use in initial experiments were fabricated on a thermally oxidized Si wafer, onto which Nb was sputter-deposited for use as the pull-electrode layer. Nb was chosen because its refractory nature would enable it to withstand the chemical and thermal conditions to be subsequently imposed for growing carbon nanotubes. A 200- nm-thick layer of SiO2 was formed on top of the Nb layer by plasma

  19. Tedisamil: master switch of nature?

    PubMed

    Doggrell, S A

    2001-01-01

    Decreasing heart rate is potentially useful in ischaemic heart disease. Tedisamil is a bradycardic agent resulting from its ability to inhibit transient outward current (I(to)) in atria. Tedisamil inhibits I(to), potassium current (IK), K(ATP) and the protein kinase A-activated chloride channel in ventricles as well as vascular IK and Ca(2+)-activated IK (IK((Ca))). Tedisamil prolongs cardiac action potentials and the corrected QT (QTc) of the ECG and also increases cardiac refractoriness. Tedisamil is anti-arrhythmic in animal models of ventricular arrhythmias and atrial flutter. The bradycardic effect of tedisamil is associated with a reduction in myocardial oxygen demand. On isolated rat ventricle, tedisamil is a positive inotrope and on isolated rabbit atria, tedisamil reverses the negative inotropic effect of pinacidil. Tedisamil contracts the isolated rat portal vein and aorta, reduces cromakalim-induced relaxations of contracted rat aorta and increases blood pressure in animals and humans. Tedisamil is 96% bound to plasma proteins, has a plasma half-life of about 10 h and is cleared from the kidney unchanged. Clinical trials have shown that the electrophysiology of tedisamil is that of a class III anti-arrhythmic. In coronary artery disease, tedisamil has no effect on inotropism and increases the threshold for angina. Potassium channel blockade with tedisamil may have advantages over calcium channel blockers or K(ATP) channel openers as an anti-ischaemic mechanism in coronary artery disease. In exercise-induced myocardial ischaemia, beta-blockers are probably favourable to tedisamil, as they will limit the increase in heart rate, contractility and blood pressure caused by sympathetic stimulation, whereas tedisamil will not. In heart failure patients, tedisamil reduces heart rate, but increases blood pressure. The usefulness of tedisamil as a bradycardic agent is limited by the increase in blood pressure. A drug that is bradycardic without increasing blood

  20. Sonic crystal acoustic switch device.

    PubMed

    Alagoz, Serkan; Alagoz, Baris Baykant

    2013-06-01

    This study reports a wave-controlled sonic crystal switch device that exhibits a destructive interference-based wave to wave reverse switching effect. By applying control waves, this acoustic device, composed of a two-dimensional square lattice sonic crystal block, reduces acoustic wave transmission from input to output. The finite difference time domain simulation and experimental results confirm the wave-to-wave reverse switching effect at the peak frequencies of the second band. The proposed sonic crystal switch prototype provides a contrast rate of 86% at 11.3 kHz frequency. This wave-to-wave switching effect is useful for controlling wave propagation for smart structure applications.

  1. Future switching satellites

    NASA Technical Reports Server (NTRS)

    Campanella, S. Joseph; Pontano, Benjamin A.; Chalmers, Harvey

    1988-01-01

    Communications satellites of the future are likely to use much narrower beams in order to increase the uplink G/T and the downlink EIRP so that small earth terminals of the VSAT class can achieve full mesh connectivity. These satellites will need onboard switches to route traffic from originating upbeams to destination downbeams. This paper presents a new approach to accomplishing this rerouting using destination-directed packets that inherently carry the information needed to control the onboard switch connections and to adjust the traffic flow among the beams and the stations. The method also inherently provides channel multiplication and DAMA advantages which result in maximally efficient utilization of the space segment resource.

  2. Switched Matrix Accelerator

    SciTech Connect

    Whittum, David H

    2000-10-04

    We describe a new concept for a microwave circuit functioning as a charged-particle accelerator at mm-wavelengths, permitting an accelerating gradient higher than conventional passive circuits can withstand consistent with cyclic fatigue. The device provides acceleration for multiple bunches in parallel channels, and permits a short exposure time for the conducting surface of the accelerating cavities. Our analysis includes scalings based on a smooth transmission line model and a complementary treatment with a coupled-cavity simulation. We provide also an electromagnetic design for the accelerating structure, arriving at rough dimensions for a seven-cell accelerator matched to standard waveguide and suitable for bench tests at low power in air at 91.392. GHz. A critical element in the concept is a fast mm-wave switch suitable for operation at high-power, and we present the considerations for implementation in an H-plane tee. We discuss the use of diamond as the photoconductor switch medium.

  3. Optical fiber switch

    DOEpatents

    Early, James W.; Lester, Charles S.

    2002-01-01

    Optical fiber switches operated by electrical activation of at least one laser light modulator through which laser light is directed into at least one polarizer are used for the sequential transport of laser light from a single laser into a plurality of optical fibers. In one embodiment of the invention, laser light from a single excitation laser is sequentially transported to a plurality of optical fibers which in turn transport the laser light to separate individual remotely located laser fuel ignitors. The invention can be operated electro-optically with no need for any mechanical or moving parts, or, alternatively, can be operated electro-mechanically. The invention can be used to switch either pulsed or continuous wave laser light.

  4. Cryogenic switched MOSFET characterization

    NASA Technical Reports Server (NTRS)

    1981-01-01

    Both p channel and n channel enhancement mode MOSFETs can be readily switched on and off at temperatures as low as 2.8 K so that switch sampled readout of a VLWIR Ge:Ga focal plane is electronically possible. Noise levels as low as 100 rms electrons per sample (independent of sample rate) can be achieved using existing p channel MOSFETs, at overall rates up to 30,000 samples/second per multiplexed channel (e.g., 32 detectors at a rate of almost 1,000 frames/second). Run of the mill devices, including very low power dissipation n channel FETs would still permit noise levels of the order of 500 electrons/sample.

  5. The quantum cryptographic switch

    NASA Astrophysics Data System (ADS)

    Srinatha, N.; Omkar, S.; Srikanth, R.; Banerjee, Subhashish; Pathak, Anirban

    2014-01-01

    We illustrate the principle of a cryptographic switch for a quantum scenario, in which a third party (Charlie) can control to a continuously varying degree the amount of information the receiver (Bob) receives, after the sender (Alice) has sent her information through a quantum channel. Suppose Charlie transmits a Bell state to Alice and Bob. Alice uses dense coding to transmit two bits to Bob. Only if the 2-bit information corresponding to the choice of the Bell state is made available by Charlie to Bob can the latter recover Alice's information. By varying the amount of information Charlie gives, he can continuously alter the information recovered by Bob. The performance of the protocol as subjected to the squeezed generalized amplitude damping channel is considered. We also present a number of practical situations where a cryptographic switch would be of use.

  6. MULTIPLE SPARK GAP SWITCH

    DOEpatents

    Schofield, A.E.

    1958-07-22

    A multiple spark gap switch of unique construction is described which will permit controlled, simultaneous discharge of several capacitors into a load. The switch construction includes a disc electrode with a plurality of protuberances of generally convex shape on one surface. A firing electrode is insulatingly supponted In each of the electrode protuberances and extends substantially to the apex thereof. Individual electrodes are disposed on an insulating plate parallel with the disc electrode to form a number of spark gaps with the protuberances. These electrodes are each connected to a separate charged capacitor and when a voltage ls applied simultaneously between the trigger electrodes and the dlsc electrode, each spark gap fires to connect its capacitor to the disc electrode and a subsequent load.

  7. Many-Body Switches

    NASA Astrophysics Data System (ADS)

    MacDonald, Allan H.

    2014-03-01

    Most current electronic devices use gate voltages to switch individual electron transport channels or off. This architecture necessarily leads to operating voltages that are much larger than the temperature thermal energy, and places lower bounds on power consumption that are becoming. I will discuss strategies for achieving devices in which gates are used to collective many-electron states, in principle allowing charge transport to be switched by smaller voltage changes and both operating voltages and power consumption to reduced. I will specifically address devices based on the properties of itinerant electroninsulating magnetic systems, and devices based on bilayer exciton condensation. This work is based on work performed in collaboration with Sanjay Banerjee and Frank Register.

  8. Automatic switching matrix

    DOEpatents

    Schlecht, Martin F.; Kassakian, John G.; Caloggero, Anthony J.; Rhodes, Bruce; Otten, David; Rasmussen, Neil

    1982-01-01

    An automatic switching matrix that includes an apertured matrix board containing a matrix of wires that can be interconnected at each aperture. Each aperture has associated therewith a conductive pin which, when fully inserted into the associated aperture, effects electrical connection between the wires within that particular aperture. Means is provided for automatically inserting the pins in a determined pattern and for removing all the pins to permit other interconnecting patterns.

  9. Composite Material Switches

    NASA Technical Reports Server (NTRS)

    Javadi, Hamid (Inventor)

    2001-01-01

    A device to protect electronic circuitry from high voltage transients is constructed from a relatively thin piece of conductive composite sandwiched between two conductors so that conduction is through the thickness of the composite piece. The device is based on the discovery that conduction through conductive composite materials in this configuration switches to a high resistance mode when exposed to voltages above a threshold voltage.

  10. CREE: Making the Switch

    SciTech Connect

    Grider, David; Palmer, John

    2014-03-06

    CREE, with the help of ARPA-E funding, has developed a Silicon Carbide (SIC) transistor which can be used to create solid state transformers capable of meeting the unique needs of the emerging smart grid. SIC transistors are different from common silicon computer chips in that they handle grid scale voltages with ease and their high frequency switching is well suited to the intermittent nature of renewable energy generation.

  11. CREE: Making the Switch

    ScienceCinema

    Grider, David; Palmer, John

    2016-07-12

    CREE, with the help of ARPA-E funding, has developed a Silicon Carbide (SIC) transistor which can be used to create solid state transformers capable of meeting the unique needs of the emerging smart grid. SIC transistors are different from common silicon computer chips in that they handle grid scale voltages with ease and their high frequency switching is well suited to the intermittent nature of renewable energy generation.

  12. Organic optical bistable switch

    NASA Astrophysics Data System (ADS)

    Xue, Jiangeng; Forrest, Stephen R.

    2003-01-01

    We demonstrate an organic optical bistable switch by integrating an efficient organic photodetector on top of a transparent electrophosphorescent organic light-emitting diode (TOLED). The bistability is achieved with an external field-effect transistor providing positive feedback. In the "LOW" state, the TOLED is off and the current in the photodetector is solely its dark current. In the "HIGH" state, the TOLED emits light that is directly coupled into the integrated photodetector through the transparent cathode. The photocurrent then is fed back to the TOLED, maintaining it in the HIGH state. The green electrophosphorescent material, fac tris(2-phenylpyridine) iridium [Ir(ppy)3] doped into a 4,4'-N,N'-dicarbazole-biphenyl host was used as the luminescent material in the TOLED, while alternating thin layers of copper phthalocyanine and 3,4,9,10-perylenetetracarboxylic bis-benzimidazole were used as the active region of the organic photodetector. The circuit has a 3 dB bandwidth of 25 kHz, and can be switched between HIGH and LOW using pulses as narrow as 60 ns. The bistable switch can be both electrically and optically reset, making it a candidate for image-retaining displays (e.g., electronic paper) and other photonic logic applications. The integrated organic device also has broad use as a linear circuit element in applications such as automatic brightness control.

  13. Cygnus Diverter Switch Analysis

    SciTech Connect

    G. Corrow, M. Hansen, D. Henderson, C. Mitton et al.

    2008-02-01

    The Cygnus Dual Beam Radiographic Facility consists of two 2.25-MV, 60-kA, 50-ns x-ray sources fielded in an underground laboratory at the Nevada Test Site. The tests performed in this laboratory involve study of the dynamic properties of plutonium and are called subcritical experiments. From end-to-end, the Cygnus machines utilize the following components: Marx generator, water-filled pulse-forming line (PFL), waterfilled coaxial transmission line (WTL), 3-cell inductive voltage adder (IVA), and rod-pinch diode. The upstream WTL interface to the PFL is via a radial insulator with coaxial geometry. The downstream WTL terminates in a manifold where the center conductor splits into three lines which individually connect to each of the IVA cell inputs. There is an impedance mismatch at this juncture. It is a concern that a reflected pulse due to anomalous behavior in the IVA or diode might initiate breakdown upon arrival at the upstream PFL/WTL insulator. Therefore near the beginning of the WTL a radial diverter switch is installed to protect the insulator from over voltage and breakdown. The diverter has adjustable gap spacing, and an in-line aqueous-solution (sodium thiosulfate) resistor array for energy dissipation. There are capacitive voltage probes at both ends of the WTL and on the diverter switch. These voltage signals will be analyzed to determine diverter performance. Using this analysis the usefulness of the diverter switch will be evaluated.

  14. Ultrafast gas switching experiments

    NASA Astrophysics Data System (ADS)

    Frost, C. A.; Martin, T. H.; Patterson, P. E.; Rinehart, L. F.; Rohwein, G. J.; Roose, L. D.; Aurand, J. F.; Buttram, M. T.

    1993-06-01

    Recent experiments which studied the physics of ultrafast gas breakdown under the extreme overvoltages which occur when a high pressure gas switch is pulse charged to hundreds of kV in 1 ns or less are described. The highly overvolted peaking gaps produce powerful electromagnetic pulses with risetimes less than 100 ps which can be used for ultrawideband radar systems, particle accelerators, laser drivers, bioelectromagnetic studies, electromagnetic effects testing, and for basic studies of gas breakdown physics. Pulses with 50 to 100 ps risetimes to peak levels of 75 to 160 kV at pulse repetition frequencies (PRF) to 1 kHz were produced and accurately measured. A unique gas switch was developed to hold off hundreds of kV with parasitic inductance less than 1 nH. An advanced diagnostic system using Fourier compensation was developed to measure single-shot risetimes below 35 ps. The complete apparatus is described and waveforms are presented. The measured data are compared with a theoretical model which predicts key features including dependence on gas species and pressure. This technology was applied to practical systems driving ultrawideband radiating antennas and bounded wave simulators. A thyristor/pulse transformer based system using a highly overvolted cable switch was developed. This pulser driving a Sandia-designed TEM cell, provides an ultra wideband impulse with less than 200 ps risetime to the test object at a PRF greater than 1 kHz at grater tha n 100 kV/m E field.

  15. "Platform switching": serendipity.

    PubMed

    Kalavathy, N; Sridevi, J; Gehlot, Roshni; Kumar, Santosh

    2014-01-01

    Implant dentistry is the latest developing field in terms of clinical techniques, research, material science and oral rehabilitation. Extensive work is being done to improve the designing of implants in order to achieve better esthetics and function. The main drawback with respect to implant restoration is achieving good osseointegration along with satisfactory stress distribution, which in turn will improve the prognosis of implant prosthesis by reducing the crestal bone loss. Many concepts have been developed with reference to surface coating of implants, surgical techniques for implant placement, immediate and delayed loading, platform switching concept, etc. This article has made an attempt to review the concept of platform switching was in fact revealed accidentally due to the nonavailability of the abutment appropriate to the size of the implant placed. A few aspect of platform switching, an upcoming idea to reduce crestal bone loss have been covered. The various methods used for locating and preparing the data were done through textbooks, Google search and related articles.

  16. Ferroelectric switching of elastin

    PubMed Central

    Liu, Yuanming; Cai, Hong-Ling; Zelisko, Matthew; Wang, Yunjie; Sun, Jinglan; Yan, Fei; Ma, Feiyue; Wang, Peiqi; Chen, Qian Nataly; Zheng, Hairong; Meng, Xiangjian; Sharma, Pradeep; Zhang, Yanhang; Li, Jiangyu

    2014-01-01

    Ferroelectricity has long been speculated to have important biological functions, although its very existence in biology has never been firmly established. Here, we present compelling evidence that elastin, the key ECM protein found in connective tissues, is ferroelectric, and we elucidate the molecular mechanism of its switching. Nanoscale piezoresponse force microscopy and macroscopic pyroelectric measurements both show that elastin retains ferroelectricity at 473 K, with polarization on the order of 1 μC/cm2, whereas coarse-grained molecular dynamics simulations predict similar polarization with a Curie temperature of 580 K, which is higher than most synthetic molecular ferroelectrics. The polarization of elastin is found to be intrinsic in tropoelastin at the monomer level, analogous to the unit cell level polarization in classical perovskite ferroelectrics, and it switches via thermally activated cooperative rotation of dipoles. Our study sheds light onto a long-standing question on ferroelectric switching in biology and establishes ferroelectricity as an important biophysical property of proteins. This is a critical first step toward resolving its physiological significance and pathological implications. PMID:24958890

  17. Ultrafast gas switching experiments

    SciTech Connect

    Frost, C.A.; Martin, T.H.; Patterson, P.E.; Rinehart, L.F.; Rohwein, G.J.; Roose, L.D.; Aurand, J.F.; Buttram, M.T.

    1993-08-01

    We describe recent experiments which studied the physics of ultrafast gas breakdown under the extreme overvoltages which occur when a high pressure gas switch is pulse charged to hundreds of kV in 1 ns or less. The highly overvolted peaking gaps produce powerful electromagnetic pulses with risetimes < 100 ps which can be used for ultrawideband radar systems, particle accelerators, laser drivers, bioelectromagnetic studies, electromagnetic effects testing, and for basic studies of gas breakdown physics. We have produced and accurately measured pulses with 50 to 100 ps risetimes to peak levels of 75 to 160 kV at pulse repetition frequencies (PRF) to 1 kHz. A unique gas switch was developed to hold off hundreds of kV with parasitic inductance less than 1 nH. An advanced diagnostic system using Fourier compensation was developed to measure single-shot risetimes below 35 ps. The complete apparatus is described and waveforms are presented. The measured data are compared with a theoretical model which predicts key features including dependence on gas species and technology to practical systems antennas and bounded wave developed a thyristor/pulse transformer based system using a highly overvolted cable switch. This pulser driving a Sandia-designed TEM cell, provides an ultra wideband impulse with < 200 ps risetime to the test object at a PRF > Khz at > 100 kV/m E field.

  18. Ultrafast gas switching experiments

    SciTech Connect

    Frost, C.A.; Martin, T.H.; Patterson, P.E.; Rinehart, L.F.; Rohwein, G.J.; Roose, L.D.; Aurand, J.F.; Buttram, M.T.

    1996-11-01

    We describe recent experiments which studied the physics of ultrafast gas breakdown under the extreme overvoltages which occur when a high pressure gas switch is pulse charged to hundreds of kV in 1 ns or less. The highly overvolted peaking gaps produce powerful electromagnetic pulses with risetimes < 100 ps which can be used for ultrawideband radar systems, particle accelerators, laser drivers, bioelectromagnetic studies, electromagnetic effects testing, and for basic studies of gas breakdown physics. We have produced and accurately measured pulses with 50 to 100 ps risetimes to peak levels of 75 to 160 kV at pulse repetition frequencies (PRF) to I kHz. A unique gas switch was developed to hold off hundreds of kV with parasitic inductance less than I nH. An advanced diagnostic system using Fourier compensation was developed to measure single-shot risetimes below 35 ps. The complete apparatus is described and wave forms are presented. The measured data are compared with a theoretical model which predicts key features including dependence on gas species and pressure. We have applied this technology to practical systems driving ultrawideband radiating antennas and bounded wave simulators. For example, we have developed a thyristor/pulse transformer based system using a highly overvolted cable switch. This pulser driving a Sandia- designed TEM cell, provides an ultra wideband impulse with < 200 ps risetime to the test object at a PRF > 1 kHz at > 100 kV/m E field.

  19. Microwave pulse compression from a storage cavity with laser-induced switching

    DOEpatents

    Bolton, Paul R.

    1992-01-01

    A laser-induced switch and a multiple cavity configuration are disclosed for producing high power microwave pulses. The microwave pulses are well controlled in wavelength and timing, with a quick rise time and a variable shape and power of the pulse. In addition, a method of reducing pre-pulse leakage to a low level is disclosed. Microwave energy is directed coherently to one or more cavities that stores the energy in a single mode, represented as a standing wave pattern. In order to switch the stored microwave energy out of the main cavity and into the branch waveguide, a laser-actuated switch is provided for the cavity. The switch includes a laser, associated optics for delivering the beam into the main cavity, and a switching gas positioned at an antinode in the main cavity. When actuated, the switching gas ionizes, creating a plasma, which becomes reflective to the microwave energy, changing the resonance of the cavity, and as a result the stored microwave energy is abruptly switched out of the cavity. The laser may directly pre-ionize the switching gas, or it may pump an impurity in the switching gas to an energy level which switches when a pre-selected cavity field is attained. Timing of switching the cavities is controlled by varying the pathlength of the actuating laser beam. For example, the pathlengths may be adjusted to output a single pulse of high power, or a series of quick lower power pulses.

  20. Photoconductive semiconductor switches: Laser Q-switch trigger and switch-trigger laser integration

    SciTech Connect

    Loubriel, G.M.; Mar, A.; Hamil, R.A.; Zutavern, F.J.; Helgeson, W.D.

    1997-12-01

    This report provides a summary of the Pulser In a Chip 9000-Discretionary LDRD. The program began in January of 1997 and concluded in September of 1997. The over-arching goal of this LDRD is to study whether laser diode triggered photoconductive semiconductor switches (PCSS) can be used to activate electro-optic devices such as Q-switches and Pockels cells and to study possible laser diode/switch integration. The PCSS switches we used were high gain GaAs switches because they can be triggered with small amounts of laser light. The specific goals of the LDRD were to demonstrate: (1) that small laser diode arrays that are potential candidates for laser-switch integration will indeed trigger the PCSS switch, and (2) that high gain GaAs switches can be used to trigger optical Q-switches in lasers such as the lasers to be used in the X-1 Advanced Radiation Source and the laser used for direct optical initiation (DOI) of explosives. The technology developed with this LDRD is now the prime candidate for triggering the Q switch in the multiple lasers in the laser trigger system of the X-1 Advanced Radiation Source and may be utilized in other accelerators. As part of the LDRD we developed a commercial supplier. To study laser/switch integration we tested triggering the high gain GaAs switches with: edge emitting laser diodes, vertical cavity surface emitting lasers (VCSELs), and transverse junction stripe (TJS) lasers. The first two types of lasers (edge emitting and VCSELs) did activate the PCSS but are harder to integrate with the PCSS for a compact package. The US lasers, while easier to integrate with the switch, did not trigger the PCSS at the US laser power levels we used. The PCSS was used to activate the Q-switch of the compact laser to be used in the X-1 Advanced Radiation Source.

  1. Development and simulation study of a new inverse-pinch high Coulomb transfer switch

    NASA Technical Reports Server (NTRS)

    Choi, Sang H.

    1989-01-01

    The inverse-pinch plasma switch was studied using a computer simulation code. The code was based on a 2-D, 2-temperature magnetohydrodynamic (MHD) model. The application of this code was limited to the disk-type inverse-pinch plasma switch. The results of the computer analysis appear to be in agreement with the experimental results when the same parameters are used. An inverse-pinch plasma switch for closing has been designed and tested for high-power switching requirements. An azimuthally uniform initiation of breakdown is a key factor in achieving an inverse-pinch current path in the switch. Thus, various types of triggers, such as trigger pins, wire-brush, ring trigger, and hypocycloidal-pinch (HCP) devices have been tested for uniform breakdown. Recently, triggering was achieved by injection of a plasma-ring (plasma puff) that is produced separately with hypocycloidal-pinch electrodes placed under the cathode of the main gap. The current paths at switch closing, initiated by the injection of a plasma-ring from the HCP trigger are azimuthally uniform, and the local current density is significantly reduced, so that damage to the electrodes and the insulator surfaces is minimized. The test results indicate that electron bombardment on the electrodes and the insulator surfaces is minimized. The test results indicate that electron bombardment on the electrodes is four orders of magnitude less than that of a spark-gap switch for the same switching power. Indeed, a few thousand shots with peak current exceeding a mega-ampere and with hold-off voltage up to 20 kV have been conducted without showing measurable damage to the electrodes and insulators.

  2. Power transistor switching characterization

    NASA Technical Reports Server (NTRS)

    Blackburn, D. L.

    1981-01-01

    The switching properties of power transistors are investigated. The devices studied were housed in IO-3 cases and were of an n(+)-p-n(-)-n(+) vertical dopant structure. The effects of the magnitude of the reverse-base current and temperature on the reverse-bias second breakdown characteristics are discussed. Brief discussions of device degradation due to second breakdown and of a constant voltage turn-off circuit are included. A description of a vacuum tube voltage clamp circuit which reduces clamped collector voltage overshoot is given.

  3. Composite Thermal Switch

    NASA Technical Reports Server (NTRS)

    McDonald, Robert; Brawn, Shelly; Harrison, Katherine; O'Toole, Shannon; Moeller, Michael

    2011-01-01

    Lithium primary and lithium ion secondary batteries provide high specific energy and energy density. The use of these batteries also helps to reduce launch weight. Both primary and secondary cells can be packaged as high-rate cells, which can present a threat to crew and equipment in the event of external or internal short circuits. Overheating of the cell interior from high current flows induced by short circuits can result in exothermic reactions in lithium primary cells and fully charged lithium ion secondary cells. Venting of the cell case, ejection of cell components, and fire have been reported in both types of cells, resulting from abuse, cell imperfections, or faulty electronic control design. A switch has been developed that consists of a thin layer of composite material made from nanoscale particles of nickel and Teflon that conducts electrons at room temperature and switches to an insulator at an elevated temperature, thus interrupting current flow to prevent thermal runaway caused by internal short circuits. The material is placed within the cell, as a thin layer incorporated within the anode and/or the cathode, to control excess currents from metal-to-metal or metal-to-carbon shorts that might result from cell crush or a manufacturing defect. The safety of high-rate cells is thus improved, preventing serious injury to personnel and sensitive equipment located near the battery. The use of recently available nanoscale particles of nickel and Teflon permits an improved, homogeneous material with the potential to be fine-tuned to a unique switch temperature, sufficiently below the onset of a catastrophic chemical reaction. The smaller particles also permit the formation of a thinner control film layer (<50 m), which can be incorporated into commercial high-rate lithium primary and secondary cells. The innovation permits incorporation in current lithium and lithium-ion cell designs with a minimal impact on cell weight and volume. The composite thermal

  4. Distributed circuit switching starnet

    SciTech Connect

    Chuan-lin Wu; Woei Lin; Min-chang Lin

    1982-01-01

    Starnet is a communication subnet which can cost-effectively connect hundreds or thousands of processors for distributed processing. It uses distributed control and circuit switching. Starnet's communication medium includes two major components: a multistage interconnection network and a set of interface units. The interconnection network uses a destination routing scheme with no central control. The interface unit provides handshaking between the computer/data node and the interconnection network under the control of a microprocessor. Detailed design of the communication medium is described. A model for comparing cost-effectiveness among starnet, crossbar and multiple buses is included. 7 references.

  5. Neutron activated switch

    DOEpatents

    Barton, David M.

    1991-01-01

    A switch for reacting quickly to a neutron emission. A rod consisting of fissionable material is located inside a vacuum tight body. An adjustable contact is located coaxially at an adjustable distance from one end of the rod. Electrical leads are connected to the rod and to the adjustable contact. With a vacuum drawn inside the body, a neutron bombardment striking the rod causes it to heat and expand longitudinally until it comes into contact with the adjustable contact. This circuit closing occurs within a period of a few microseconds.

  6. Railway switch transport model.

    PubMed

    Horvat, Martin; Prosen, Tomaž; Benenti, Giuliano; Casati, Giulio

    2012-11-01

    We propose a simple model of coupled heat and particle transport based on zero-dimensional classical deterministic dynamics, which is reminiscent of a railway switch whose action is a function only of the particle's energy. It is shown that already in the minimal three-terminal model, where the second terminal is considered as a probe with zero net particle and heat currents, one can find extremely asymmetric Onsager matrices as a consequence of time-reversal symmetry breaking of the model. This minimalistic transport model provides a better understanding of thermoelectric heat engines in the presence of time-reversal symmetry breaking.

  7. Butyrate Infusions in the Ovine Fetus Delay the Biologic Clock for Globin Gene Switching

    NASA Astrophysics Data System (ADS)

    Perrine, Susan P.; Rudolph, Abraham; Faller, Douglas V.; Roman, Christine; Cohen, Ruth A.; Chen, Shao-Jing; Kan, Yuet Wai

    1988-11-01

    The switch from fetal to adult hemoglobin expression is regulated in many mammalian species by a developmental clock-like mechanism and determined by the gestational age of the fetus. Prolonging fetal globin gene expression is of considerable interest for therapeutic potential in diseases caused by abnormal β -globin genes. Butyric acid, which is found in increased plasma concentrations in infants of diabetic mothers who have delayed globin gene switching, was infused into catheterized fetal lambs in utero during the time of the normal globin gene switch period. The globin gene switch was significantly delayed in three of four butyrate-treated fetuses compared with controls and was entirely prevented in one fetus in whom the infusion was begun before the globin switch was under way. These data provide a model for investigating and arresting the biologic clock of hemoglobin switching.

  8. Compound semiconductor optical waveguide switch

    DOEpatents

    Spahn, Olga B.; Sullivan, Charles T.; Garcia, Ernest J.

    2003-06-10

    An optical waveguide switch is disclosed which is formed from III-V compound semiconductors and which has a moveable optical waveguide with a cantilevered portion that can be bent laterally by an integral electrostatic actuator to route an optical signal (i.e. light) between the moveable optical waveguide and one of a plurality of fixed optical waveguides. A plurality of optical waveguide switches can be formed on a common substrate and interconnected to form an optical switching network.

  9. Wide Bandgap Extrinsic Photoconductive Switches

    DTIC Science & Technology

    2007-06-01

    above band-gap wavelengths of light to trigger the switches. The performance and switch life of lateral geometry PCSS are limited by surface flashover ...Laboratory Livermore, CA 94550 Abstract Semi-insulating Silicon Carbide and Gallium Nitride are attractive materials for compact, high voltage...Introduction Previous SiC PCSS work [2-4] used high resistivity, low impurity SiC polytypes and focused on lateral geometry surface switches that used

  10. Investigation on properties of ultrafast switching in a bulk gallium arsenide avalanche semiconductor switch

    SciTech Connect

    Hu, Long; Su, Jiancang; Ding, Zhenjie; Hao, Qingsong; Yuan, Xuelin

    2014-03-07

    Properties of ultrafast switching in a bulk gallium arsenide (GaAs) avalanche semiconductor switch based on semi-insulating wafer, triggered by an optical pulse, were analyzed using physics-based numerical simulations. It has been demonstrated that when a voltage with amplitude of 5.2 kV is applied, after an exciting optical pulse with energy of 1 μJ arrival, the structure with thickness of 650 μm reaches a high conductivity state within 110 ps. Carriers are created due to photons absorption, and electrons and holes drift to anode and cathode terminals, respectively. Static ionizing domains appear both at anode and cathode terminals, and create impact-generated carriers which contribute to the formation of electron-hole plasma along entire channel. When the electric field in plasma region increases above the critical value (∼4 kV/cm) at which the electrons drift velocity peaks, a domain comes into being. An increase in carrier concentration due to avalanche multiplication in the domains reduces the domain width and results in the formation of an additional domain as soon as the field outside the domains increases above ∼4 kV/cm. The formation and evolution of multiple powerfully avalanching domains observed in the simulations are the physical reasons of ultrafast switching. The switch exhibits delayed breakdown with the characteristics affected by biased electric field, current density, and optical pulse energy. The dependence of threshold energy of the exciting optical pulse on the biased electric field is discussed.

  11. Optical switch based on thermocapillarity

    NASA Astrophysics Data System (ADS)

    Sakata, Tomomi; Makihara, Mitsuhiro; Togo, Hiroyoshi; Shimokawa, Fusao; Kaneko, Kazumasa

    2001-11-01

    Space-division optical switches are essential for the protection, optical cross-connects (OXCs), and optical add/drop multiplexers (OADMs) needed in future fiber-optic communication networks. For applications in these areas, we proposed a thermocapillarity switch called oil-latching interfacial-tension variation effect (OLIVE) switch. An OLIVE switch is a micro-mechanical optical switch fabricated on planar lightwave circuits (PLC) using micro-electro-mechanical systems (MEMS) technology. It consists of a crossing waveguide that has a groove at each crossing point and a pair of microheaters. The groove is partially filled with the refractive-index-matching liquid, and optical signals are switched according to the liquid's position in the groove, i.e., whether it is passing straight through the groove or reflecting at the sidewall of the groove. The liquid is driven by thermocapillarity and latched by capillarity. Using the total internal reflection to switch the optical path, the OLIVE switch exhibits excellent optical characteristics, such as high transparency (insertion loss: < 2 dB), high extinction ratio (> 50 dB), and low crosstalk (< -50 dB). Moreover, since this switch has a simple structure and bi-stability, it has wide variety of applications in wavelength division multiplexing (WDM) networks.

  12. Simultaneous determination of phentermine and topiramate in human plasma by liquid chromatography-tandem mass spectrometry with positive/negative ion-switching electrospray ionization and its application in pharmacokinetic study.

    PubMed

    Ni, Yang; Zhou, Ying; Xu, Mingzhen; He, Xiaomeng; Li, Huqun; Haseeb, Satter; Chen, Hui; Li, Weiyong

    2015-03-25

    A new method for simultaneous determination of phentermine and topiramate by liquid chromatography/electrospray tandem mass spectrometry (LC/MS/MS) operated in positive and negative ionization switching modes was developed and validated. Protein precipitation with acetonitrile was selected for sample preparation. Analyses were performed on a liquid chromatography system employing a Kromasil 60-5CN column (2.1 mm × 100 mm, 5 μm) and an isocratic elution with mixed solution of acetonitrile-20mM ammonium formate containing 0.3% formic acid (40:60, v/v), at a flow rate of 0.35 mL/min. Doxazosin mesylate and pioglitazone were used as the internal standard (IS) respectively for quantification. The determination was carried out on an API 4000 triple-quadrupole mass spectrometer operated in multiple reaction monitoring (MRM) mode using the following transitions monitored simultaneously: positive m/z 150.0/91.0 for phentermine, m/z 452.1/344.3 for doxazosin, and negative m/z 338.3/77.9 for topiramate, m/z 355.0/41.9 for pioglitazone. The method was validated to be linear over the concentration range of 1-800 ng mL(-1) for phentermine, 1-1000 ng mL(-1) for topiramate. Within- and between-day accuracy and precision of the validated method at three different concentration levels were within the acceptable limits of <15% at all concentrations. Blood samples were collected into heparinized tubes before and after administration. The simple and robust LC/MS/MS method was successfully applied for the simultaneous determination of phentermine and topiramate in a pharmacokinetic study in healthy male Chinese volunteers.

  13. Neuromorphic atomic switch networks.

    PubMed

    Avizienis, Audrius V; Sillin, Henry O; Martin-Olmos, Cristina; Shieh, Hsien Hang; Aono, Masakazu; Stieg, Adam Z; Gimzewski, James K

    2012-01-01

    Efforts to emulate the formidable information processing capabilities of the brain through neuromorphic engineering have been bolstered by recent progress in the fabrication of nonlinear, nanoscale circuit elements that exhibit synapse-like operational characteristics. However, conventional fabrication techniques are unable to efficiently generate structures with the highly complex interconnectivity found in biological neuronal networks. Here we demonstrate the physical realization of a self-assembled neuromorphic device which implements basic concepts of systems neuroscience through a hardware-based platform comprised of over a billion interconnected atomic-switch inorganic synapses embedded in a complex network of silver nanowires. Observations of network activation and passive harmonic generation demonstrate a collective response to input stimulus in agreement with recent theoretical predictions. Further, emergent behaviors unique to the complex network of atomic switches and akin to brain function are observed, namely spatially distributed memory, recurrent dynamics and the activation of feedforward subnetworks. These devices display the functional characteristics required for implementing unconventional, biologically and neurally inspired computational methodologies in a synthetic experimental system.

  14. Neuromorphic Atomic Switch Networks

    PubMed Central

    Martin-Olmos, Cristina; Shieh, Hsien Hang; Aono, Masakazu; Stieg, Adam Z.; Gimzewski, James K.

    2012-01-01

    Efforts to emulate the formidable information processing capabilities of the brain through neuromorphic engineering have been bolstered by recent progress in the fabrication of nonlinear, nanoscale circuit elements that exhibit synapse-like operational characteristics. However, conventional fabrication techniques are unable to efficiently generate structures with the highly complex interconnectivity found in biological neuronal networks. Here we demonstrate the physical realization of a self-assembled neuromorphic device which implements basic concepts of systems neuroscience through a hardware-based platform comprised of over a billion interconnected atomic-switch inorganic synapses embedded in a complex network of silver nanowires. Observations of network activation and passive harmonic generation demonstrate a collective response to input stimulus in agreement with recent theoretical predictions. Further, emergent behaviors unique to the complex network of atomic switches and akin to brain function are observed, namely spatially distributed memory, recurrent dynamics and the activation of feedforward subnetworks. These devices display the functional characteristics required for implementing unconventional, biologically and neurally inspired computational methodologies in a synthetic experimental system. PMID:22880101

  15. Data center coolant switch

    DOEpatents

    Iyengar, Madhusudan K.; Parida, Pritish R.; Schultz, Mark D.

    2015-10-06

    A data center cooling system is operated in a first mode; it has an indoor portion wherein heat is absorbed from components in the data center, and an outdoor heat exchanger portion wherein outside air is used to cool a first heat transfer fluid (e.g., water) present in at least the outdoor heat exchanger portion of the cooling system during the first mode. The first heat transfer fluid is a relatively high performance heat transfer fluid (as compared to the second fluid), and has a first heat transfer fluid freezing point. A determination is made that an appropriate time has been reached to switch from the first mode to a second mode. Based on this determination, the outdoor heat exchanger portion of the data cooling system is switched to a second heat transfer fluid, which is a relatively low performance heat transfer fluid, as compared to the first heat transfer fluid. It has a second heat transfer fluid freezing point lower than the first heat transfer fluid freezing point, and the second heat transfer fluid freezing point is sufficiently low to operate without freezing when the outdoor air temperature drops below a first predetermined relationship with the first heat transfer fluid freezing point.

  16. Task switching: effects of practice on switch and mixing costs.

    PubMed

    Strobach, Tilo; Liepelt, Roman; Schubert, Torsten; Kiesel, Andrea

    2012-01-01

    In the task-switching paradigm, mixing costs indicate the performance costs to mix two different tasks, while switch costs indicate the performance costs to switch between two sequentially presented tasks. Applying tasks with bivalent stimuli and responses, many studies demonstrated substantial mixing and switch costs and a reduction of these costs as a result of practice. The present study investigates whether extensive practice of a task-switching situation including tasks with univalent stimuli eliminates these costs. Participants practiced switching between a visual and an auditory task. These tasks were chosen because they had shown eliminated performance costs in a comparable dual-task practice study (Schumacher et al. Psychol Sci 12:101-108, 2001). Participants either performed the tasks with univalent responses (i.e., visual-manual and auditory-verbal stimulus-response mappings) or bivalent responses (i.e., visual-manual and auditory-manual stimulus-response mappings). Both valence conditions revealed substantial mixing and switch costs at the beginning of practice, yet, mixing costs were largely eliminated after eight practice sessions while switch costs were still existent.

  17. Phasic alertness and residual switch costs in task switching.

    PubMed

    Schneider, Darryl W

    2017-02-01

    Residual switch costs are deficits in task-switching performance that occur despite considerable time to prepare for a task switch. In the present study, the author investigated whether increased phasic alertness modulates residual switch costs. In 2 experiments involving the task-cuing procedure, subjects performed numerical categorization tasks on target digits, with and without an alerting stimulus presented shortly before the target (alert and no-alert trials, respectively). Switch costs were obtained that decreased with a longer cue-target interval, indicating subjects engaged in preparation, but large residual switch costs remained. Alerting effects were obtained in the form of faster overall performance on alert than on no-alert trials, indicating the alerting stimuli increased phasic alertness. Critically, residual switch costs were similar on alert and no-alert trials in both experiments, unaffected by manipulations of alert type, alert availability, and alert-target interval. Implications of the results for understanding the relationship between phasic alertness and cognitive control in task switching are discussed. (PsycINFO Database Record

  18. Tuning the temperature dependence for switching in dithienylethene photochromic switches.

    PubMed

    Kudernac, Tibor; Kobayashi, Takao; Uyama, Ayaka; Uchida, Kingo; Nakamura, Shinichiro; Feringa, Ben L

    2013-08-29

    Diarylethene photochromic switches use light to drive structural changes through reversible electrocyclization reactions. High efficiency in dynamic photoswitching is a prerequisite for applications, as is thermal stability and the selective addressability of both isomers ring-opened and -closed diarylethenes. These properties can be optimized readily through rational variation in molecular structure. The efficiency with regard to switching as a function of structural variation is much less understood, with the exception of geometric requirements placed on the reacting atoms. Ultimately, increasing the quantum efficiency of photochemical switching in diarylethenes requires a detailed understanding of the excited-state potential energy surface(s) and the mechanisms involved in switching. Through studies of the temperature dependence, photoswitching and theoretical studies demonstrate the occurrence or absence of thermal activation barriers in three constitutional isomers that bear distinct π-conjugated systems. We found that a decrease in the thermal barriers correlates with an increase in switching efficiency. The origin of the barriers is assigned to the decrease in π-conjugation that is concomitant with the progress of the photoreaction. Furthermore, we show that balanced molecular design can minimize the change in the extent of π-conjugation during switching and lead to optimal bidirectional switching efficiencies. Our findings hold implications for future structural design of diarylethene photochromic switches.

  19. The redox switch/redox coupling hypothesis.

    PubMed

    Cerdán, Sebastián; Rodrigues, Tiago B; Sierra, Alejandra; Benito, Marina; Fonseca, Luis L; Fonseca, Carla P; García-Martín, María L

    2006-01-01

    We provide an integrative interpretation of neuroglial metabolic coupling including the presence of subcellular compartmentation of pyruvate and monocarboxylate recycling through the plasma membrane of both neurons and glial cells. The subcellular compartmentation of pyruvate allows neurons and astrocytes to select between glucose and lactate as alternative substrates, depending on their relative extracellular concentration and the operation of a redox switch. This mechanism is based on the inhibition of glycolysis at the level of glyceraldehyde 3-phosphate dehydrogenase by NAD(+) limitation, under sufficiently reduced cytosolic NAD(+)/NADH redox conditions. Lactate and pyruvate recycling through the plasma membrane allows the return to the extracellular medium of cytosolic monocarboxylates enabling their transcellular, reversible, exchange between neurons and astrocytes. Together, intracellular pyruvate compartmentation and monocarboxylate recycling result in an effective transcellular coupling between the cytosolic NAD(+)/NADH redox states of both neurons and glial cells. Following glutamatergic neurotransmission, increased glutamate uptake by the astrocytes is proposed to augment glycolysis and tricarboxylic acid cycle activity, balancing to a reduced cytosolic NAD(+)/NADH in the glia. Reducing equivalents are transferred then to the neuron resulting in a reduced neuronal NAD(+)/NADH redox state. This may eventually switch off neuronal glycolysis, favoring the oxidation of extracellular lactate in the lactate dehydrogenase (LDH) equilibrium and in the neuronal tricarboxylic acid cycles. Finally, pyruvate derived from neuronal lactate oxidation, may return to the extracellular space and to the astrocyte, restoring the basal redox state and beginning a new loop of the lactate/pyruvate transcellular coupling cycle. Transcellular redox coupling operates through the plasma membrane transporters of monocarboxylates, similarly to the intracellular redox shuttles

  20. A continuous switching model for piezoelectric state switching methods

    NASA Astrophysics Data System (ADS)

    Lopp, Garrett K.; Kauffman, Jeffrey L.

    2017-04-01

    Piezoelectric-based, semi-active vibration reduction approaches have been studied for over a decade due to their potential in controlling vibration over a large frequency range. Previous studies have relied on a discrete model when switching between the stiffness states of the system. In such a modeling approach, the energy dissipation of the stored potential energy and the transient dynamics, in general, are not well understood. In this paper, a switching model is presented using a variable capacitance in the attached shunt circuit. When the switch duration is small in comparison to the period of vibration, the vibration reduction performance approaches that of the discrete model with an instantaneous switch, whereas longer switch durations lead to less vibration reduction. An energy analysis is then performed that results in the appearance of an energy dissipation term due to the varying capacitance in the shunt circuit.

  1. A high capacity satellite switched TDMA microwave switch matrix

    NASA Technical Reports Server (NTRS)

    Cory, B. J.; Berkowitz, M.

    1981-01-01

    A description is given of the conceptual design of a high-capacity satellite switched-time division multiple access (SS-TDMA) microwave switch matrix fabricated with GaAs monolithic microwave integrated circuits (MMICs), including integration of both microwave and control logic circuits into the monolithic design. The technology required for a 30/20 GHz communications system includes an on-board SS-TDMA switch matrix. A conceptual design study that has been completed for a wideband, high-capacity (typically 100 x 100) channel switch matrix using technology anticipated for 1987 is described, noting that the study resulted in a switch matrix design concept using a coupled crossbar architecture implemented with MMIC. The design involves basic building block MMIC, permitting flexible growth and efficient wraparound redundancy to increase reliability.

  2. Hybrid switch for resonant power converters

    DOEpatents

    Lai, Jih-Sheng; Yu, Wensong

    2014-09-09

    A hybrid switch comprising two semiconductor switches connected in parallel but having different voltage drop characteristics as a function of current facilitates attainment of zero voltage switching and reduces conduction losses to complement reduction of switching losses achieved through zero voltage switching in power converters such as high-current inverters.

  3. 14 CFR 27.1145 - Ignition switches.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Ignition switches. 27.1145 Section 27.1145... switches. (a) There must be means to quickly shut off all ignition by the grouping of switches or by a master ignition control. (b) Each group of ignition switches, except ignition switches for...

  4. 14 CFR 27.1145 - Ignition switches.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Ignition switches. 27.1145 Section 27.1145... switches. (a) There must be means to quickly shut off all ignition by the grouping of switches or by a master ignition control. (b) Each group of ignition switches, except ignition switches for...

  5. 14 CFR 23.1145 - Ignition switches.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Ignition switches. 23.1145 Section 23.1145... Accessories § 23.1145 Ignition switches. (a) Ignition switches must control and shut off each ignition circuit... the grouping of switches or by a master ignition control. (c) Each group of ignition switches,...

  6. 14 CFR 23.1145 - Ignition switches.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Ignition switches. 23.1145 Section 23.1145... Accessories § 23.1145 Ignition switches. (a) Ignition switches must control and shut off each ignition circuit... the grouping of switches or by a master ignition control. (c) Each group of ignition switches,...

  7. 14 CFR 27.1145 - Ignition switches.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Ignition switches. 27.1145 Section 27.1145... switches. (a) There must be means to quickly shut off all ignition by the grouping of switches or by a master ignition control. (b) Each group of ignition switches, except ignition switches for...

  8. 14 CFR 23.1145 - Ignition switches.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Ignition switches. 23.1145 Section 23.1145... Accessories § 23.1145 Ignition switches. (a) Ignition switches must control and shut off each ignition circuit... the grouping of switches or by a master ignition control. (c) Each group of ignition switches,...

  9. 14 CFR 27.1145 - Ignition switches.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Ignition switches. 27.1145 Section 27.1145... switches. (a) There must be means to quickly shut off all ignition by the grouping of switches or by a master ignition control. (b) Each group of ignition switches, except ignition switches for...

  10. 14 CFR 23.1145 - Ignition switches.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Ignition switches. 23.1145 Section 23.1145... Accessories § 23.1145 Ignition switches. (a) Ignition switches must control and shut off each ignition circuit... the grouping of switches or by a master ignition control. (c) Each group of ignition switches,...

  11. 14 CFR 23.1145 - Ignition switches.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Ignition switches. 23.1145 Section 23.1145... Accessories § 23.1145 Ignition switches. (a) Ignition switches must control and shut off each ignition circuit... the grouping of switches or by a master ignition control. (c) Each group of ignition switches,...

  12. 14 CFR 27.1145 - Ignition switches.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Ignition switches. 27.1145 Section 27.1145... switches. (a) There must be means to quickly shut off all ignition by the grouping of switches or by a master ignition control. (b) Each group of ignition switches, except ignition switches for...

  13. Switching languages, switching palabras (words): an electrophysiological study of code switching.

    PubMed

    Moreno, Eva M; Federmeier, Kara D; Kutas, Marta

    2002-02-01

    Switching languages has often been associated with a processing cost. In this study, the authors used event-related potentials to compare switches between two languages with within-language lexical switches as bilinguals read for comprehension. Stimuli included English sentences and idioms ending either with the expected English words, their Spanish translations (code switches), or English synonyms (lexical switches). As expected, lexical switches specifically enhanced the N400 response in both context types. Code switches, by contrast, elicited an increased negativity over left fronto-central sites in the regular nonidiomatic sentences (250-450 ms) and a large posterior positivity (450-850 ms) in both context types. In addition, both lexical and code switches elicited a late frontal positivity (650-850 ms) relative to expected completions, especially in idioms. Analysis of the individual response patterns showed correlations with vocabulary skills in English and in Spanish. Overall, the electrophysiological data suggest that for some speakers in some contexts, the processing of a code switch may actually be less costly than the processing of an unexpected within-language item.

  14. Phenotypic switching in bacteria

    NASA Astrophysics Data System (ADS)

    Merrin, Jack

    Living matter is a non-equilibrium system in which many components work in parallel to perpetuate themselves through a fluctuating environment. Physiological states or functionalities revealed by a particular environment are called phenotypes. Transitions between phenotypes may occur either spontaneously or via interaction with the environment. Even in the same environment, genetically identical bacteria can exhibit different phenotypes of a continuous or discrete nature. In this thesis, we pursued three lines of investigation into discrete phenotypic heterogeneity in bacterial populations: the quantitative characterization of the so-called bacterial persistence, a theoretical model of phenotypic switching based on those measurements, and the design of artificial genetic networks which implement this model. Persistence is the phenotype of a subpopulation of bacteria with a reduced sensitivity to antibiotics. We developed a microfluidic apparatus, which allowed us to monitor the growth rates of individual cells while applying repeated cycles of antibiotic treatments. We were able to identify distinct phenotypes (normal and persistent) and characterize the stochastic transitions between them. We also found that phenotypic heterogeneity was present prior to any environmental cue such as antibiotic exposure. Motivated by the experiments with persisters, we formulated a theoretical model describing the dynamic behavior of several discrete phenotypes in a periodically varying environment. This theoretical framework allowed us to quantitatively predict the fitness of dynamic populations and to compare survival strategies according to environmental time-symmetries. These calculations suggested that persistence is a strategy used by bacterial populations to adapt to fluctuating environments. Knowledge of the phenotypic transition rates for persistence may provide statistical information about the typical environments of bacteria. We also describe a design of artificial

  15. EDITORIAL: Molecular switches at surfaces Molecular switches at surfaces

    NASA Astrophysics Data System (ADS)

    Weinelt, Martin; von Oppen, Felix

    2012-10-01

    In nature, molecules exploit interaction with their environment to realize complex functionalities on the nanometer length scale. Physical, chemical and/or biological specificity is frequently achieved by the switching of molecules between microscopically different states. Paradigmatic examples are the energy production in proton pumps of bacteria or the signal conversion in human vision, which rely on switching molecules between different configurations or conformations by external stimuli. The remarkable reproducibility and unparalleled fatigue resistance of these natural processes makes it highly desirable to emulate nature and develop artificial systems with molecular functionalities. A promising avenue towards this goal is to anchor the molecular switches at surfaces, offering new pathways to control their functional properties, to apply electrical contacts, or to integrate switches into larger systems. Anchoring at surfaces allows one to access the full range from individual molecular switches to self-assembled monolayers of well-defined geometry and to customize the coupling between molecules and substrate or between adsorbed molecules. Progress in this field requires both synthesis and preparation of appropriate molecular systems and control over suitable external stimuli, such as light, heat, or electrical currents. To optimize switching and generate function, it is essential to unravel the geometric structure, the electronic properties and the dynamic interactions of the molecular switches on surfaces. This special section, Molecular Switches at Surfaces, collects 17 contributions describing different aspects of this research field. They analyze elementary processes, both in single molecules and in ensembles of molecules, which involve molecular switching and concomitant changes of optical, electronic, or magnetic properties. Two topical reviews summarize the current status, including both challenges and achievements in the field of molecular switches on

  16. Study of optoelectronic switch for satellite-switched time-division multiple access

    NASA Technical Reports Server (NTRS)

    Su, Shing-Fong; Jou, Liz; Lenart, Joe

    1987-01-01

    The use of optoelectronic switching for satellite switched time division multiple access will improve the isolation and reduce the crosstalk of an IF switch matrix. The results are presented of a study on optoelectronic switching. Tasks include literature search, system requirements study, candidate switching architecture analysis, and switch model optimization. The results show that the power divided and crossbar switching architectures are good candidates for an IF switch matrix.

  17. Switch energies of electronic and optical switches: A simple comparative study

    SciTech Connect

    Thylen, L.; Palm, T. . Lab. of Photonics and Microwave Engineering)

    1994-05-01

    A comparison of the switch energies of electrically controlled optical absorption switches and electronic switches is performed. It is shown that in the investigated case with quantum box based absorption switches, the switch energies of the optical switches are generally orders of magnitude larger than those of the electronic switches for very high frequencies. Consequences on integration of optical devices as well as on the potential for photonic switching and processing are briefly discussed.

  18. Battery switch for downhole tools

    DOEpatents

    Boling, Brian E.

    2010-02-23

    An electrical circuit for a downhole tool may include a battery, a load electrically connected to the battery, and at least one switch electrically connected in series with the battery and to the load. The at least one switch may be configured to close when a tool temperature exceeds a selected temperature.

  19. Optimized scalable network switch

    DOEpatents

    Blumrich, Matthias A.; Chen, Dong; Coteus, Paul W.; Gara, Alan G.; Giampapa, Mark E.; Heidelberger, Philip; Steinmacher-Burow, Burkhard D.; Takken, Todd E.; Vranas, Pavlos M.

    2007-12-04

    In a massively parallel computing system having a plurality of nodes configured in m multi-dimensions, each node including a computing device, a method for routing packets towards their destination nodes is provided which includes generating at least one of a 2m plurality of compact bit vectors containing information derived from downstream nodes. A multilevel arbitration process in which downstream information stored in the compact vectors, such as link status information and fullness of downstream buffers, is used to determine a preferred direction and virtual channel for packet transmission. Preferred direction ranges are encoded and virtual channels are selected by examining the plurality of compact bit vectors. This dynamic routing method eliminates the necessity of routing tables, thus enhancing scalability of the switch.

  20. MIRO Calibration Switch Mechanism

    NASA Technical Reports Server (NTRS)

    Suchman, Jason; Salinas, Yuki; Kubo, Holly

    2001-01-01

    The Jet Propulsion Laboratory has designed, analyzed, built, and tested a calibration switch mechanism for the MIRO instrument on the ROSETTA spacecraft. MIRO is the Microwave Instrument for the Rosetta Orbiter; this instrument hopes to investigate the origin of the solar system by studying the origin of comets. Specifically, the instrument will be the first to use submillimeter and millimeter wave heterodyne receivers to remotely examine the P-54 Wirtanen comet. In order to calibrate the instrument, it needs to view a hot and cold target. The purpose of the mechanism is to divert the instrument's field of view from the hot target, to the cold target, and then back into space. This cycle is to be repeated every 30 minutes for the duration of the 1.5 year mission. The paper describes the development of the mechanism, as well as analysis and testing techniques.

  1. ''Smart'' watchdog safety switch

    DOEpatents

    Kronberg, J.W.

    1991-10-01

    A method and apparatus for monitoring a process having a periodic output so that the process equipment is not damaged in the event of a controller failure, comprising a low-pass and peak clipping filter, an event detector that generates an event pulse for each valid change in magnitude of the filtered periodic output, a timing pulse generator, a counter that increments upon receipt of any timing pulse and resets to zero on receipt of any event pulse, an alarm that alerts when the count reaches some preselected total count, and a set of relays that opens to stop power to process equipment. An interface module can be added to allow the switch to accept a variety of periodic output signals. 21 figures.

  2. "Smart" watchdog safety switch

    DOEpatents

    Kronberg, James W.

    1991-01-01

    A method and apparatus for monitoring a process having a periodic output so that the process equipment is not damaged in the event of a controller failure, comprising a low-pass and peak clipping filter, an event detector that generates an event pulse for each valid change in magnitude of the filtered periodic output, a timing pulse generator, a counter that increments upon receipt of any timing pulse and resets to zero on receipt of any event pulse, an alarm that alerts when the count reaches some preselected total count, and a set of relays that opens to stop power to process equipment. An interface module can be added to allow the switch to accept a variety of periodic output signals.

  3. FAST OPENING SWITCH

    DOEpatents

    Bender, M.; Bennett, F.K.; Kuckes, A.F.

    1963-09-17

    A fast-acting electric switch is described for rapidly opening a circuit carrying large amounts of electrical power. A thin, conducting foil bridges a gap in this circuit and means are provided for producing a magnetic field and eddy currents in the foil, whereby the foil is rapidly broken to open the circuit across the gap. Advantageously the foil has a hole forming two narrow portions in the foil and the means producing the magnetic field and eddy currents comprises an annular coil having its annulus coaxial with the hole in the foil and turns adjacent the narrow portions of the foil. An electrical current flows through the coil to produce the magnetic field and eddy currents in the foil. (AEC)

  4. High voltage coaxial switch

    DOEpatents

    Rink, John P.

    1983-07-19

    A coaxial high voltage, high current switch having a solid cylindrical cold cathode coaxially surrounded by a thin hollow cylindrical inner electrode and a larger hollow cylindrical outer electrode. A high voltage trigger between the cathode and the inner electrode causes electrons to be emitted from the cathode and flow to the inner electrode preferably through a vacuum. Some of the electrons penetrate the inner electrode and cause a volumetric discharge in the gas (which may be merely air) between the inner and outer electrodes. The discharge provides a low impedance path between a high voltage charge placed on the outer electrode and a load (which may be a high power laser) coupled to the inner electrode. For high repetition rate the gas between the inner and outer electrodes may be continuously exchanged or refreshed under pressure.

  5. High voltage coaxial switch

    DOEpatents

    Rink, J.P.

    1983-07-19

    A coaxial high voltage, high current switch having a solid cylindrical cold cathode coaxially surrounded by a thin hollow cylindrical inner electrode and a larger hollow cylindrical outer electrode. A high voltage trigger between the cathode and the inner electrode causes electrons to be emitted from the cathode and flow to the inner electrode preferably through a vacuum. Some of the electrons penetrate the inner electrode and cause a volumetric discharge in the gas (which may be merely air) between the inner and outer electrodes. The discharge provides a low impedance path between a high voltage charge placed on the outer electrode and a load (which may be a high power laser) coupled to the inner electrode. For high repetition rate the gas between the inner and outer electrodes may be continuously exchanged or refreshed under pressure. 3 figs.

  6. Optimized scalable network switch

    DOEpatents

    Blumrich, Matthias A.; Chen, Dong; Coteus, Paul W.

    2010-02-23

    In a massively parallel computing system having a plurality of nodes configured in m multi-dimensions, each node including a computing device, a method for routing packets towards their destination nodes is provided which includes generating at least one of a 2m plurality of compact bit vectors containing information derived from downstream nodes. A multilevel arbitration process in which downstream information stored in the compact vectors, such as link status information and fullness of downstream buffers, is used to determine a preferred direction and virtual channel for packet transmission. Preferred direction ranges are encoded and virtual channels are selected by examining the plurality of compact bit vectors. This dynamic routing method eliminates the necessity of routing tables, thus enhancing scalability of the switch.

  7. 49 CFR 236.6 - Hand-operated switch equipped with switch circuit controller.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Hand-operated switch equipped with switch circuit..., AND APPLIANCES Rules and Instructions: All Systems General § 236.6 Hand-operated switch equipped with switch circuit controller. Hand-operated switch equipped with switch circuit controller connected to the...

  8. 49 CFR 236.6 - Hand-operated switch equipped with switch circuit controller.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Hand-operated switch equipped with switch circuit..., AND APPLIANCES Rules and Instructions: All Systems General § 236.6 Hand-operated switch equipped with switch circuit controller. Hand-operated switch equipped with switch circuit controller connected to the...

  9. 49 CFR 236.6 - Hand-operated switch equipped with switch circuit controller.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Hand-operated switch equipped with switch circuit..., AND APPLIANCES Rules and Instructions: All Systems General § 236.6 Hand-operated switch equipped with switch circuit controller. Hand-operated switch equipped with switch circuit controller connected to the...

  10. 49 CFR 236.6 - Hand-operated switch equipped with switch circuit controller.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Hand-operated switch equipped with switch circuit..., AND APPLIANCES Rules and Instructions: All Systems General § 236.6 Hand-operated switch equipped with switch circuit controller. Hand-operated switch equipped with switch circuit controller connected to the...

  11. Operation of a Homeostatic Sleep Switch

    PubMed Central

    Talbot, Clifford B.; Song, Seoho M.; Thurston, Alexander J. F.; Miesenböck, Gero

    2016-01-01

    Sleep disconnects animals from the external world, at considerable risks and costs that must be offset by a vital benefit. Insight into this mysterious benefit will come from understanding sleep homeostasis: to monitor sleep need, an internal bookkeeper must track physiological changes that are linked to the core function of sleep1. In Drosophila, a crucial component of the machinery for sleep homeostasis is a cluster of neurons innervating the dorsal fan-shaped body (dFB) of the central complex2,3. Artificial activation of these cells induces sleep2, whereas reductions in excitability cause insomnia3,4. dFB neurons in sleep-deprived flies tend to be electrically active, with high input resistances and long membrane time constants, while neurons in rested flies tend to be electrically silent3. Correlative evidence thus supports the simple view that homeostatic sleep control works by switching sleep-promoting neurons between active and quiescent states3. Here we demonstrate state switching by dFB neurons, identify dopamine as a neuromodulator that operates the switch, and delineate the switching mechanism. Arousing dopamine4–8 caused transient hyperpolarization of dFB neurons within tens of milliseconds and lasting excitability suppression within minutes. Both effects were transduced by Dop1R2 receptors and mediated by potassium conductances. The switch to electrical silence involved the downregulation of voltage-gated A-type currents carried by Shaker and Shab and the upregulation of voltage-independent leak currents through a two-pore domain potassium channel we term Sandman. Sandman is encoded by the CG8713 gene and translocates to the plasma membrane in response to dopamine. dFB-restricted interference with the expression of Shaker or Sandman decreased or increased sleep, respectively, by slowing the repetitive discharge of dFB neurons in the ON state or blocking their entry into the OFF state. Biophysical changes in a small population of neurons are thus

  12. Switching Phenomena in a System with No Switches

    NASA Astrophysics Data System (ADS)

    Preis, Tobias; Stanley, H. Eugene

    2010-02-01

    It is widely believed that switching phenomena require switches, but this is actually not true. For an intriguing variety of switching phenomena in nature, the underlying complex system abruptly changes from one state to another in a highly discontinuous fashion. For example, financial market fluctuations are characterized by many abrupt switchings creating increasing trends ("bubble formation") and decreasing trends ("financial collapse"). Such switching occurs on time scales ranging from macroscopic bubbles persisting for hundreds of days to microscopic bubbles persisting only for a few seconds. We analyze a database containing 13,991,275 German DAX Future transactions recorded with a time resolution of 10 msec. For comparison, a database providing 2,592,531 of all S&P500 daily closing prices is used. We ask whether these ubiquitous switching phenomena have quantifiable features independent of the time horizon studied. We find striking scale-free behavior of the volatility after each switching occurs. We interpret our findings as being consistent with time-dependent collective behavior of financial market participants. We test the possible universality of our result by performing a parallel analysis of fluctuations in transaction volume and time intervals between trades. We show that these financial market switching processes have properties similar to those of phase transitions. We suggest that the well-known catastrophic bubbles that occur on large time scales—such as the most recent financial crisis—are no outliers but single dramatic representatives caused by the switching between upward and downward trends on time scales varying over nine orders of magnitude from very large (≈102 days) down to very small (≈10 ms).

  13. High-Voltage, High-Power Gaseous Electronics Switch For Electric Grid Power Conversion

    NASA Astrophysics Data System (ADS)

    Sommerer, Timothy J.

    2014-05-01

    We are developing a high-voltage, high-power gas switch for use in low-cost power conversion terminals on the electric power grid. Direct-current (dc) power transmission has many advantages over alternating current (ac) transmission, but at present the high cost of ac-dc power interconversion limits the use of dc. The gas switch we are developing conducts current through a magnetized cold cathode plasma in hydrogen or helium to reach practical current densities > 1 A/cm2. Thermal and sputter damage of the cathode by the incident ion flux is a major technical risk, and is being addressed through use of a ``self-healing'' liquid metal cathode (eg, gallium). Plasma conditions and cathode sputtering loss are estimated by analyzing plasma spectral emission. A particle-in-cell plasma model is used to understand various aspects of switch operation, including the conduction phase (where plasma densities can exceed 1013 cm-3), the switch-open phase (where the high-voltage must be held against gas breakdown on the left side of Paschen's curve), and the switching transitions (especially the opening process, which is initiated by forming an ion-matrix sheath adjacent to a control grid). The information, data, or work presented herein was funded in part by the Advanced Research Projects Agency-Energy (ARPA-E), U.S. Department of Energy, under Award Number DE-AR0000298.

  14. Keep flexible - Keep switching! The influence of forced task switching on voluntary task switching.

    PubMed

    Fröber, Kerstin; Dreisbach, Gesine

    2017-05-01

    Goal directed behavior depends on a dynamic balance between cognitive flexibility and stability. Identifying factors that modulate the balance between these control states is therefore of major interest for the understanding of human action control. In two experiments we used a hybrid paradigm combining forced- and free-choice task switching and measured spontaneous voluntary switch rate (VSR) as an indicator of cognitive flexibility. In Experiment 1 participants were free to choose a given task on 75%, 50%, or 25% of all trials. In the remaining forced-choice trials task repetitions and switches were roughly equally distributed. Results showed that VSR increases with increasing proportion of forced choices. To clarify whether the frequency of forced choices per se or the frequency of forced task switches in particular drives this effect we conducted Experiment 2. In a fully orthogonal between design participants were free to choose a given task on 75% or 25% of all trials with a predetermined switch rate in the remaining forced-choice trials of 75% or 25%, respectively. Results revealed an interaction of both manipulations: The highest VSR was found for the combination of 75% forced-choice trials with 75% forced switch rate, while VSR for 75% forced-choice trials with 25% forced switch rate was still higher than VSRs in both conditions with 25% forced-choice trials. This suggests that a context of frequent forced task switching changes global control parameters towards more flexible behavior. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Channelized coplanar waveguide pin-diode switches

    NASA Technical Reports Server (NTRS)

    Ponchak, G. E.; Simons, R. N.

    1989-01-01

    Three different types of p-i-n diode, reflective CPW switches are presented. The first two switches are the series and the shunt mounted diode switches. Each has achieved greater than 15 dB of isolation over a broad bandwidth. The third switch is a narrow band, high isolation switched filter which has achieved 19 dB of isolation. Equivalent circuits and measured performance for each switch is presented.

  16. Liquid metal switches for electromagnetic railgun systems

    SciTech Connect

    Mitcham, A.J.; Prothero, D.H.; Brooks, J.C. )

    1991-01-01

    The need for a reliable and effective commutating switch is essential to the operation of an HPG-driven railgun system. This switch must offer the lowest possible resistance during the current build up time and then must commutate the current quickly and efficiently into the railgun barrel. This paper considers the essential requirements for such a switch and, after briefly reviewing the available switch technologies, describes a new type of switch based on a liquid metal switching medium.

  17. Modeling the Conductivity of a Subnanosecond Breakdown Gas Switch

    NASA Astrophysics Data System (ADS)

    Chen, Jinhui; Scott Tyo, J.; Jerald Buchenauer, C.

    We present two different modeling methods for understanding subnanosecond breakdown processes in gas plasma switches. The first method uses a finite element time domain method in order to understand experimental measurements of the remote electromagnetic (EM) fields. This method only models the EM fields and is good for analysis, but lacks a predictive capability for the full nonlinear plasma system. The second modeling method uses a PIC code, and is fully self consistent. We make comparisons with experimental measurements and conclude that the PIC model may provide a good understanding of the subnanosecond breakdown phenomena.

  18. Two-mode interference photonic switch for WDM communications

    NASA Astrophysics Data System (ADS)

    Li, Baojun; Chua, Soo-Jin

    2002-07-01

    A two-mode interference photonic switch with high carrier injection has been designed and fabricated based on free-carrier plasma dispersion effect. It consists of an input Y-branch single-mode ridge waveguide, a two-mode waveguide coupling section, and an output Y-branch single-mode ridge waveguide. The boron doped silicon-germanium material was grown by molecular beam epitaxy and the devices were fabricated by using standard silicon technology. The ridge waveguides were formed by reactive ion etching technique and the input and output facets of the waveguides were ground and polished by a mechanical method. The switch was characterized by using a 1310 nm InGaAsP/InP hetero-structure laser diode. Its insertion loss and On-state crosstalk were measured to be 2.74 and -15.5 dB, respectively, at a total switching current of 110 mA. The switching time is 180 ns and the fastest switching time is up to 30 ns.

  19. Scaling experiments on a magnetically insulated thermionic vacuum switch

    SciTech Connect

    Eninger, J.E.; Vanderberg, B.H.

    1994-12-31

    Magnetic insulation of the electron flow in a cylindrical thermionic vacuum diode has been proposed as a way to achieve a fast high-voltage high-power opening switch. The expected performance of this type of device can be derived from a set of basic scaling laws combined with empirical relationships obtained from experimental studies. Switch losses are mainly due to anode dissipation W{sub a}, which can be normalized to the transferred pulse energy. Leakage current and switch hold-off voltage depend on device geometry, materials, vacuum conditions etc and must be determined experimentally. For this purpose, the MX-1 experiment has been designed and operated. This device is basically a smooth-bore cylindrical magnetron with a 5 cm radius, 400 cm{sup 2} area thermionic dispenser cathode separated from the coaxial water-cooled anode by a few mm wide gap. This design allows pulsed operation at up to {approximately}100 kV, {approximately}4 kA and average power levels of {approximately}1 MW. The MX-1 switch is used as an opening switch to produce 1--2 {mu}s long square pulses from an inductive storage PFN. The current-voltage characteristics of the switch are determined as a function of the applied magnetic field and load condition. Plasma wave measurements are performed to investigate the stability of the electron flow. Results are summarized in the form of scaling diagrams for the important switch parameters, showing possible performance levels and physical and technical limitations identified as far in this work.

  20. Alarm toe switch. [Patent application

    DOEpatents

    Ganyard, F.P.

    1980-11-18

    An alarm toe switch inserted within a shoe for energizing an alarm circuit in a covert manner includes an insole mounting pad into which a miniature reed switch is fixedly molded. An elongated slot perpendicular to the reed switch is formed in the bottom surface of the mounting pad. A permanent cylindrical magnet positioned in the forward portion of the slot with a diameter greater than the pad thickness causes a bump above the pad. A foam rubber block is also positioned in the slot rearwardly of the magnet and holds the magnet in normal inoperative relation. A non-magnetic support plate covers the slot and holds the magnet and foam rubber in the slot. The plate minimizes bending and frictional forces to improve movement of the magnet for reliable switch activation. The bump occupies the knuckle space beneath the big toe. When the big toe is scrunched rearwardly the magnet is moved within the slot relative to the reed switch, thus magnetically activating the switch. When toe pressure is released the foam rubber block forces the magnet back into normal inoperative position to deactivate the reed switch.

  1. Multiscroll attractors by switching systems.

    PubMed

    Campos-Cantón, E; Barajas-Ramírez, J G; Solís-Perales, G; Femat, R

    2010-03-01

    In this paper, we present a class of three-dimensional dynamical systems having multiscrolls which we call unstable dissipative systems (UDSs). The UDSs are dissipative in one of its components but unstable in the other two. This class of systems is constructed with a switching law to display various multiscroll strange attractors. The multiscroll strange attractors result from the combination of several unstable "one-spiral" trajectories by means of switching. Each of these trajectories lies around a saddle hyperbolic stationary point. Thus, we describe how a piecewise-linear switching system yields multiscroll attractors, symmetric or asymmetric, with chaotic behavior.

  2. Technology development of RF MEMS switches on printed circuit boards

    NASA Astrophysics Data System (ADS)

    Chang, Hung-Pin

    Today, some engineers have shifted their focus on the micro-electro-mechanical system (MEMS) to pursue better technological advancements. Recent development in RF MEMS technologies have lead to superior switch characteristics, i.e., very low insertion loss, very low power requirements, and high isolation comparing to the conventional semiconductor devices. This success has promised the potential of MEMS to revolutionize RF and microwave system implementation for the next generation of communication applications. However, RF MEMS switches integrated monolithically with various RF functional components on the same substrate to create multifunctional and reconfigurable complete communication systems remains to be a challenge research topic due to the concerns of the high cost of packaging process and the high cost of RF matching requirements in module board implementation. Furthermore, the fabrication of most RF MEMS switches requires thickness control and surface planarization of wide metal lines prior to deposition of a metal membrane bridge, which poses a major challenge to manufacturability. To ease the fabrication of RF MEMS switches and to facilitate their integration with other RF components such as antennas, phase delay lines, tunable filters, it is imperative to develop a manufacturable RF MEMS switch technology on a common substrate housing all essential RF components. Development of a novel RF MEMS technology to build a RF MEMS switch and provide a system-level packaging on microwave laminated printed circuit boards (PCBs) are proposed in this dissertation. Two key processes, high-density inductively coupled plasma chemical vapor deposition (HDICP CVD) for low temperature dielectric deposition, and compressive molding planarization (COMP) for the temporary sacrificial polymer planarization have been developed for fabricating RF MEMS switches on PCBs. Several membrane-type capacitive switches have been fabricated showing excellent RF performance and dynamic

  3. Low impedance switch

    DOEpatents

    Hornig, Donald F.

    1976-01-01

    1. A low inductance switch comprising a pair of spaced apart, annularly shaped, plate members of conducting material supported in substantially parallel, insulated relationship, said plate members being provided with a plurality of radially extending, spoke-like extensions whereby said members may be connected into a plurality of electrical circuits, and an electrical discharge means connected across said spaced plate members for effecting the simultaneous closing of the electrical circuits connected thereto, said electrical discharge means including an elongated, sealed envelope which contains an ionizable gas and which is supported on one of said plate members with the major axis of said envelope extending generally perpendicular to the plane of said plate members, a pair of elongated, spaced apart, insulated electrodes supported within said envelope and extending axially thereof, one of said electrodes being connected to each of said plate members, and a third, firing or trigger electrode supported within said envelope intermediate said main electrodes and being insulated from said main electrodes.

  4. Regenerative switching CMOS system

    DOEpatents

    Welch, James D.

    1998-01-01

    Complementary Metal Oxide Semiconductor (CMOS) Schottky barrier Field Effect Transistor systems, which are a seriesed combination of N and P-Channel MOSFETS, in which Source Schottky barrier junctions of the N and P-Channel Schottky barrier MOSFETS are electically interconnected, (rather than the Drains as in conventional diffused junction CMOS), which Schottky barrier MOSFET system demonstrates Regenerative Inverting Switching Characteristics in use are disclosed. Both the N and P-Channel Schottky barrier MOSFET devices are unique in that they provide operational Drain Current vs. Drain to Source voltage as a function of Gate voltage only where the polarities of the Drain voltage and Gate voltage are opposite, referenced to the Source as a common terminal, and where the polarity of the voltage applied to the Gate is appropriate to cause Channel inversion. Experimentally derived results which demonstrate and verify the operation of N and P-Channel Schottky barrier MOSFETS actually fabricated on P and N-type Silicon respectively, by a common procedure using vacuum deposited Chromium as a Schottky barrier forming metal, are also provided.

  5. Regenerative switching CMOS system

    DOEpatents

    Welch, J.D.

    1998-06-02

    Complementary Metal Oxide Semiconductor (CMOS) Schottky barrier Field Effect Transistor systems, which are a series combination of N and P-Channel MOSFETS, in which Source Schottky barrier junctions of the N and P-Channel Schottky barrier MOSFETS are electrically interconnected, (rather than the Drains as in conventional diffused junction CMOS), which Schottky barrier MOSFET system demonstrates Regenerative Inverting Switching Characteristics in use are disclosed. Both the N and P-Channel Schottky barrier MOSFET devices are unique in that they provide operational Drain Current vs. Drain to Source voltage as a function of Gate voltage only where the polarities of the Drain voltage and Gate voltage are opposite, referenced to the Source as a common terminal, and where the polarity of the voltage applied to the Gate is appropriate to cause Channel inversion. Experimentally derived results which demonstrate and verify the operation of N and P-Channel Schottky barrier MOSFETS actually fabricated on P and N-type Silicon respectively, by a common procedure using vacuum deposited Chromium as a Schottky barrier forming metal, are also provided. 14 figs.

  6. The magnetoelectrochemical switch.

    PubMed

    Popa, Petru Lunca; Kemp, Neil T; Majjad, Hicham; Dalmas, Guillaume; Faramarzi, Vina; Andreas, Christian; Hertel, Riccardo; Doudin, Bernard

    2014-07-22

    In the field of spintronics, the archetype solid-state two-terminal device is the spin valve, where the resistance is controlled by the magnetization configuration. We show here how this concept of spin-dependent switch can be extended to magnetic electrodes in solution, by magnetic control of their chemical environment. Appropriate nanoscale design allows a huge enhancement of the magnetic force field experienced by paramagnetic molecular species in solutions, which changes between repulsive and attractive on changing the electrodes' magnetic orientations. Specifically, the field gradient force created within a sub-100-nm-sized nanogap separating two magnetic electrodes can be reversed by changing the orientation of the electrodes' magnetization relative to the current flowing between the electrodes. This can result in a breaking or making of an electric nanocontact, with a change of resistance by a factor of up to 10(3). The results reveal how an external field can impact chemical equilibrium in the vicinity of nanoscale magnetic circuits.

  7. The magnetoelectrochemical switch

    PubMed Central

    Lunca Popa, Petru; Kemp, Neil T.; Majjad, Hicham; Dalmas, Guillaume; Faramarzi, Vina; Andreas, Christian; Hertel, Riccardo; Doudin, Bernard

    2014-01-01

    In the field of spintronics, the archetype solid-state two-terminal device is the spin valve, where the resistance is controlled by the magnetization configuration. We show here how this concept of spin-dependent switch can be extended to magnetic electrodes in solution, by magnetic control of their chemical environment. Appropriate nanoscale design allows a huge enhancement of the magnetic force field experienced by paramagnetic molecular species in solutions, which changes between repulsive and attractive on changing the electrodes’ magnetic orientations. Specifically, the field gradient force created within a sub-100-nm-sized nanogap separating two magnetic electrodes can be reversed by changing the orientation of the electrodes’ magnetization relative to the current flowing between the electrodes. This can result in a breaking or making of an electric nanocontact, with a change of resistance by a factor of up to 103. The results reveal how an external field can impact chemical equilibrium in the vicinity of nanoscale magnetic circuits. PMID:25009179

  8. Electrically switched ion exchange

    SciTech Connect

    Lilga, M.A.; Schwartz, D.T.; Genders, D.

    1997-10-01

    A variety of waste types containing radioactive {sup 137}Cs are found throughout the DOE complex. These waste types include water in reactor cooling basins, radioactive high-level waste (HLW) in underground storage tanks, and groundwater. Safety and regulatory requirements and economics require the removal of radiocesium before these wastes can be permanently disposed of. Electrically Switched Ion Exchange (ESIX) is an approach for radioactive cesium separation that combines IX and electrochemistry to provide a selective, reversible, and economic separation method that also produces little or no secondary waste. In the ESIX process, an electroactive IX film is deposited electrochemically onto a high-surface area electrode, and ion uptake and elution are controlled directly by modulating the potential of the film. For cesium, the electroactive films under investigation are ferrocyanides, which are well known to have high selectivities for cesium in concentrated sodium solutions. When a cathode potential is applied to the film, Fe{sup +3} is reduced to the Fe{sup +2} state, and a cation must be intercalated into the film to maintain charge neutrality (i.e., Cs{sup +} is loaded). Conversely, if an anodic potential is applied, a cation must be released from the film (i.e., Cs{sup +} is unloaded). Therefore, to load the film with cesium, the film is simply reduced; to unload cesium, the film is oxidized.

  9. Toward pulsed power uses for photoconductive semiconductor switches: Closing switches

    SciTech Connect

    Loubriel, G.M.; O'Malley, M.W.; Zutavern, F.J.

    1987-01-01

    Recent results on Photoconductive Semiconductor Switches (PCSS) are presented. For Si and GaAs switches surface flashover, contact degradation, and current limitations are addressed. For Si samples have been obtained that, without being triggered, withstand fields of up to 85 kV/cm produced by an approx.2-..mu..s wide voltage pulse. The 1-inch diameter, Si samples (''gap length'' of 1.5 cm) have been switched at 36 kV/cm (approx. =54 kV) into an approx.30-..cap omega.. load with a current of 703 A. For GaAs, most samples can withstand, without being triggered, 100 kV/cm. At low electric fields the GaAs samples behave as switches that close during the laser pulse and then open in nanoseconds. At high voltages GaAs does not open. In this mode, called lock-on, up to 42.7 kV/cm (64.1 kV) has been switched. The lock-on mode can be triggered with small laser powers. Plans are being made to use large arrays of GaAs samples to switch 1 MV and 156 kA.

  10. Self-assembled nanostructured resistive switching memory devices fabricated by templated bottom-up growth

    PubMed Central

    Song, Ji-Min; Lee, Jang-Sik

    2016-01-01

    Metal-oxide-based resistive switching memory device has been studied intensively due to its potential to satisfy the requirements of next-generation memory devices. Active research has been done on the materials and device structures of resistive switching memory devices that meet the requirements of high density, fast switching speed, and reliable data storage. In this study, resistive switching memory devices were fabricated with nano-template-assisted bottom up growth. The electrochemical deposition was adopted to achieve the bottom-up growth of nickel nanodot electrodes. Nickel oxide layer was formed by oxygen plasma treatment of nickel nanodots at low temperature. The structures of fabricated nanoscale memory devices were analyzed with scanning electron microscope and atomic force microscope (AFM). The electrical characteristics of the devices were directly measured using conductive AFM. This work demonstrates the fabrication of resistive switching memory devices using self-assembled nanoscale masks and nanomateirals growth from bottom-up electrochemical deposition. PMID:26739122

  11. Self-assembled nanostructured resistive switching memory devices fabricated by templated bottom-up growth.

    PubMed

    Song, Ji-Min; Lee, Jang-Sik

    2016-01-07

    Metal-oxide-based resistive switching memory device has been studied intensively due to its potential to satisfy the requirements of next-generation memory devices. Active research has been done on the materials and device structures of resistive switching memory devices that meet the requirements of high density, fast switching speed, and reliable data storage. In this study, resistive switching memory devices were fabricated with nano-template-assisted bottom up growth. The electrochemical deposition was adopted to achieve the bottom-up growth of nickel nanodot electrodes. Nickel oxide layer was formed by oxygen plasma treatment of nickel nanodots at low temperature. The structures of fabricated nanoscale memory devices were analyzed with scanning electron microscope and atomic force microscope (AFM). The electrical characteristics of the devices were directly measured using conductive AFM. This work demonstrates the fabrication of resistive switching memory devices using self-assembled nanoscale masks and nanomateirals growth from bottom-up electrochemical deposition.

  12. Low voltage operation of plasma focus.

    PubMed

    Shukla, Rohit; Sharma, S K; Banerjee, P; Das, R; Deb, P; Prabahar, T; Das, B K; Adhikary, B; Shyam, A

    2010-08-01

    Plasma foci of compact sizes and operating with low energies (from tens of joules to few hundred joules) have found application in recent years and have attracted plasma-physics scientists and engineers for research in this direction. We are presenting a low energy and miniature plasma focus which operates from a capacitor bank of 8.4 muF capacity, charged at 4.2-4.3 kV and delivering approximately 52 kA peak current at approximately 60 nH calculated circuit inductance. The total circuit inductance includes the plasma focus inductance. The reported plasma focus operates at the lowest voltage among all reported plasma foci so far. Moreover the cost of capacitor bank used for plasma focus is nearly 20 U.S. dollars making it very cheap. At low voltage operation of plasma focus, the initial breakdown mechanism becomes important for operation of plasma focus. The quartz glass tube is used as insulator and breakdown initiation is done on its surface. The total energy of the plasma focus is approximately 75 J. The plasma focus system is made compact and the switching of capacitor bank energy is done by manual operating switch. The focus is operated with hydrogen and deuterium filled at 1-2 mbar.

  13. Task Switching versus Cue Switching: Using Transition Cuing to Disentangle Sequential Effects in Task-Switching Performance

    ERIC Educational Resources Information Center

    Schneider, Darryl W.; Logan, Gordon D.

    2007-01-01

    Recent methodological advances have allowed researchers to address confounds in the measurement of task-switch costs in task-switching performance by dissociating cue switching from task switching. For example, in the transition-cuing procedure, which involves presenting cues for task transitions rather than for tasks, cue transitions (cue…

  14. Hobetron current regulating switch tube

    SciTech Connect

    True, R.B.; Hansen, R.J.; Deb, D.N.; Good, G.R.; Reass, W.A.

    1999-07-01

    This paper describes a novel high power electron tube that can hold off voltages up to hundreds of kilovolts, and switch hundreds of amps of current. They call the divide the Hobertron since it utilizes a hollow electron beam. Unlike magnetron injection gun (MIG) switch tubes, it does not require a magnet. Further, it uses nonintercepting control laments, and a dispenser cathode for long life and reliability. Finally, it features a double walled Faraday cage collector for high power dissipation capability. Current is very tightly controlled against changes in voltage across the switch (it is an almost perfect pentode), thus this tube is ideally suited for direct series switching applications. In the paper, various Hobertron designs, and the computer codes and methods used to create them, will be described.

  15. Biomolecular switches: Driven to peak

    NASA Astrophysics Data System (ADS)

    Tu, Yuhai

    2017-07-01

    A curious peak in the distribution describing stochastic switching in bacterial motility had researchers confounded. But a careful study performed under varying mechanical conditions has now revealed that the breaking of detailed balance is to blame.

  16. Wide Bandgap Extrinsic Photoconductive Switches

    SciTech Connect

    Sullivan, James S.

    2012-01-20

    Photoconductive semiconductor switches (PCSS) have been investigated since the late 1970s. Some devices have been developed that withstand tens of kilovolts and others that switch hundreds of amperes. However, no single device has been developed that can reliably withstand both high voltage and switch high current. Yet, photoconductive switches still hold the promise of reliable high voltage and high current operation with subnanosecond risetimes. Particularly since good quality, bulk, single crystal, wide bandgap semiconductor materials have recently become available. In this chapter we will review the basic operation of PCSS devices, status of PCSS devices and properties of the wide bandgap semiconductors 4H-SiC, 6H-SiC and 2H-GaN.

  17. Characterisation of the current switch mechanism in two-stage wire array Z-pinches

    NASA Astrophysics Data System (ADS)

    Burdiak, G. C.; Lebedev, S. V.; Harvey-Thompson, A. J.; Hall, G. N.; Swadling, G. F.; Suzuki-Vidal, F.; Khoory, E.; Bland, S. N.; Pickworth, L.; de Grouchy, P.; Skidmore, J.; Suttle, L.; Waisman, E. M.

    2015-11-01

    In this paper, we describe the operation of a two-stage wire array z-pinch driven by the 1.4 MA, 240 ns rise-time Magpie pulsed-power device at Imperial College London. In this setup, an inverse wire array acts as a fast current switch, delivering a current pre-pulse into a cylindrical load wire array, before rapidly switching the majority of the generator current into the load after a 100-150 ns dwell time. A detailed analysis of the evolution of the load array during the pre-pulse is presented. Measurements of the load resistivity and energy deposition suggest significant bulk heating of the array mass occurs. The ˜5 kA pre-pulse delivers ˜0.8 J of energy to the load, leaving it in a mixed, predominantly liquid-vapour state. The main current switch occurs as the inverse array begins to explode and plasma expands into the load region. Electrical and imaging diagnostics indicate that the main current switch may evolve in part as a plasma flow switch, driven by the expansion of a magnetic cavity and plasma bubble along the length of the load array. Analysis of implosion trajectories suggests that approximately 1 MA switches into the load in 100 ns, corresponding to a doubling of the generator dI/dt. Potential scaling of the device to higher current machines is discussed.

  18. Characterisation of the current switch mechanism in two-stage wire array Z-pinches

    SciTech Connect

    Burdiak, G. C.; Lebedev, S. V.; Harvey-Thompson, A. J.; Hall, G. N.; Swadling, G. F.; Suzuki-Vidal, F.; Khoory, E.; Bland, S. N.; Pickworth, L.; Grouchy, P. de; Skidmore, J.; Suttle, L.; Waisman, E. M.

    2015-11-15

    In this paper, we describe the operation of a two-stage wire array z-pinch driven by the 1.4 MA, 240 ns rise-time Magpie pulsed-power device at Imperial College London. In this setup, an inverse wire array acts as a fast current switch, delivering a current pre-pulse into a cylindrical load wire array, before rapidly switching the majority of the generator current into the load after a 100–150 ns dwell time. A detailed analysis of the evolution of the load array during the pre-pulse is presented. Measurements of the load resistivity and energy deposition suggest significant bulk heating of the array mass occurs. The ∼5 kA pre-pulse delivers ∼0.8 J of energy to the load, leaving it in a mixed, predominantly liquid-vapour state. The main current switch occurs as the inverse array begins to explode and plasma expands into the load region. Electrical and imaging diagnostics indicate that the main current switch may evolve in part as a plasma flow switch, driven by the expansion of a magnetic cavity and plasma bubble along the length of the load array. Analysis of implosion trajectories suggests that approximately 1 MA switches into the load in 100 ns, corresponding to a doubling of the generator dI/dt. Potential scaling of the device to higher current machines is discussed.

  19. Target Plasma Formation for Magnetic Compression/Magnetized Target Fusion

    NASA Astrophysics Data System (ADS)

    Lindemuth, I. R.; Reinovsky, R. E.; Chrien, R. E.; Christian, J. M.; Ekdahl, C. A.; Goforth, J. H.; Haight, R. C.; Idzorek, G.; King, N. S.; Kirkpatrick, R. C.; Larson, R. E.; Morgan, G. L.; Olinger, B. W.; Oona, H.; Sheehey, P. T.; Shlachter, J. S.; Smith, R. C.; Veeser, L. R.; Warthen, B. J.; Younger, S. M.; Chernyshev, V. K.; Mokhov, V. N.; Demin, A. N.; Dolin, Y. N.; Garanin, S. F.; Ivanov, V. A.; Korchagin, V. P.; Mikhailov, O. D.; Morozov, I. V.; Pak, S. V.; Pavlovskii, E. S.; Seleznev, N. Y.; Skobelev, A. N.; Volkov, G. I.; Yakubov, V. A.

    1995-09-01

    Experimental observations of plasma behavior in a novel plasma formation chamber are reported. Experimental results are in reasonable agreement with two-dimensional magnetohydrodynamic computations suggesting that the plasma could subsequently be adiabatically compressed by a magnetically driven pusher to yield 1 GJ of fusion energy. An explosively driven helical flux compression generator mated with a unique closing switch/opening switch combination delivered a 2.7 MA, 347 μs magnetization current and an additional 5 MA, 2.5 μs electrical pulse to the chamber. A hot plasma was produced and 1013 D-T fusion reactions were observed.

  20. High PRF high current switch

    DOEpatents

    Moran, Stuart L.; Hutcherson, R. Kenneth

    1990-03-27

    A triggerable, high voltage, high current, spark gap switch for use in pu power systems. The device comprises a pair of electrodes in a high pressure hydrogen environment that is triggered by introducing an arc between one electrode and a trigger pin. Unusually high repetition rates may be obtained by undervolting the switch, i.e., operating the trigger at voltages much below the self-breakdown voltage of the device.

  1. A Piezoelectric Cryogenic Heat Switch

    NASA Technical Reports Server (NTRS)

    Jahromi, Amir E.; Sullivan, Dan F.

    2014-01-01

    We have measured the thermal conductance of a mechanical heat switch actuated by a piezoelectric positioner, the PZHS (PieZo electric Heat Switch), at cryogenic temperatures. The thermal conductance of the PZHS was measured between 4 K and 10 K, and on/off conductance ratios greater than 100 were achieved when the positioner applied its maximum force of 8 N. We discuss the advantages of using this system in cryogenic applications, and estimate the ultimate performance of an optimized PZHS.

  2. Asymmetry in mechanical polarization switching

    NASA Astrophysics Data System (ADS)

    Lu, Haidong; Liu, Shi; Ye, Ziyu; Yasui, Shintaro; Funakubo, Hiroshi; Rappe, Andrew M.; Gruverman, Alexei

    2017-05-01

    Recent demonstration of a mechanical 180° switching of ferroelectric polarization has enabled an alternative polarization control mechanism based on the flexoelectric coupling between polarization and strain gradient. Mechanical switching is a highly asymmetric phenomenon associated with the inhomogeneous strain induced by an atomic force microscope (AFM) tip pressed against the ferroelectric surface. Here, we demonstrate the asymmetric domain switching behavior in the vicinity of the 180° domain wall in PbTiO3 thin films with respect to the AFM tip scanning direction. The writing-direction-dependent asymmetric domain response has been modeled by molecular dynamics simulation showing asymmetry in domain wall displacement due to the difference in the volume of mechanically switched domains. The obtained results show that the mechanically induced switching dynamics is very different from the conventional 180° switching realized by an external electric field and has to be exploited differently. In particular, nanoscale domain engineering via the tip-induced flexoelectric effect requires careful consideration of asymmetric interaction between the existing domain structures and the strain gradient.

  3. K-Band Latching Switches

    NASA Technical Reports Server (NTRS)

    Piotrowski, W. S.; Raue, J. E.

    1984-01-01

    Design, development, and tests are described for two single-pole-double-throw latching waveguide ferrite switches: a K-band switch in WR-42 waveguide and a Ka-band switch in WR-28 waveguide. Both switches have structurally simple junctions, mechanically interlocked without the use of bonding materials; they are impervious to the effects of thermal, shock, and vibration stresses. Ferrite material for the Ka-band switch with a proper combination of magnetic and dielectric properties was available and resulted in excellent low loss, wideband performance. The high power handling requirement of the K-band switch limited the choice of ferrite to nickel-zinc compositions with adequate magnetic properties, but with too low relative dielectric constant. The relative dielectric constant determines the junction dimensions for given frequency responses. In this case the too low value unavoidably leads to a larger than optimum junction volume, increasing the insertion loss and restricting the operating bandwidth. Efforts to overcome the materials-related difficulties through the design of a composite junction with increased effective dielectric properties efforts to modify the relative dielectric constant of nickel-zinc ferrite are examined.

  4. Sealed reed relay limit switches

    NASA Astrophysics Data System (ADS)

    Ivanov, I. P.; Svintsov, G. P.; Yefimova, M. A.; Lebedev, A. V.; Samsonov, Y. P.

    1986-01-01

    Sealed reed relay limit switches are described which overcome the inherent deficiencies traditionally present in these devices: high material, labor consumption, and difficult operation. Series VSG limit switches developed at the All-Union Scientific Research and Technological Planning Institute for Relay Engineering (Cheboksary) for use in buildings are described. The VSG1 has a single switching contact, the VSG2 a single normally open contact, and the VSG3 a single normally closed contact. The VSG1 employs type MKS-27103 sealed reed relays, while the VSG2 and VSG3 employ KEM-1 reed relays. The magnet system, which consists of magnets and a plate, and the sealed reed relay are contained in a nonmagnetic casing with a slit in it. The mathematical expression defining the geometric dimensions of the magnet system is given. The basic parameteres of all three types of switches are tabulated. The VSG series switches can be used to replace VBK and BVK switches, thus saving electricity, labor, and materials, including silver.

  5. Vanadium dioxide phase change switches

    NASA Astrophysics Data System (ADS)

    Field, M.; Hillman, C.; Stupar, P.; Hacker, J.; Griffith, Z.; Lee, K.-J.

    2015-05-01

    The thermally driven metal insulator transition in vanadium dioxide (VO2) is used to create a low loss millimeter wave switch which operates up to and beyond W-band frequencies. We have built RF switches using vanadium dioxide thin films fabricated within a section of inverted transmission line with integrated on chip heaters to provide local thermal control. On heating the films above the metal insulator transition we obtain record low switch insertion loss of 0.13 dB at 50 GHz and 0.5 dB at 110 GHz. The switch cut-off frequency is high, fc ~ 45 THz, due to the low on state resistance and off state capacitance. We have investigated the device physics of these switches including self-latching of the devices under high RF powers, and demonstrated their integration with silicon germanium RF circuits where the switch heater current sources and control logic are also integrated into the same silicon germanium circuit.

  6. K-band latching switches

    NASA Astrophysics Data System (ADS)

    Piotrowski, W. S.; Raue, J. E.

    1984-05-01

    Design, development, and tests are described for two single-pole-double-throw latching waveguide ferrite switches: a K-band switch in WR-42 waveguide and a Ka-band switch in WR-28 waveguide. Both switches have structurally simple junctions, mechanically interlocked without the use of bonding materials; they are impervious to the effects of thermal, shock, and vibration stresses. Ferrite material for the Ka-band switch with a proper combination of magnetic and dielectric properties was available and resulted in excellent low loss, wideband performance. The high power handling requirement of the K-band switch limited the choice of ferrite to nickel-zinc compositions with adequate magnetic properties, but with too low relative dielectric constant. The relative dielectric constant determines the junction dimensions for given frequency responses. In this case the too low value unavoidably leads to a larger than optimum junction volume, increasing the insertion loss and restricting the operating bandwidth. Efforts to overcome the materials-related difficulties through the design of a composite junction with increased effective dielectric properties efforts to modify the relative dielectric constant of nickel-zinc ferrite are examined.

  7. 14 CFR 29.1145 - Ignition switches.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Ignition switches. 29.1145 Section 29.1145... switches. (a) Ignition switches must control each ignition circuit on each engine. (b) There must be means to quickly shut off all ignition by the grouping of switches or by a master ignition control....

  8. 14 CFR 25.1145 - Ignition switches.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Ignition switches. 25.1145 Section 25.1145... switches. (a) Ignition switches must control each engine ignition circuit on each engine. (b) There must be means to quickly shut off all ignition by the grouping of switches or by a master ignition control....

  9. 14 CFR 25.1145 - Ignition switches.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Ignition switches. 25.1145 Section 25.1145... switches. (a) Ignition switches must control each engine ignition circuit on each engine. (b) There must be means to quickly shut off all ignition by the grouping of switches or by a master ignition control....

  10. 14 CFR 29.1145 - Ignition switches.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Ignition switches. 29.1145 Section 29.1145... switches. (a) Ignition switches must control each ignition circuit on each engine. (b) There must be means to quickly shut off all ignition by the grouping of switches or by a master ignition control....

  11. Working Memory Costs of Task Switching

    ERIC Educational Resources Information Center

    Liefooghe, Baptist; Barrouillet, Pierre; Vandierendonck, Andre; Camos, Valerie

    2008-01-01

    Although many accounts of task switching emphasize the importance of working memory as a substantial source of the switch cost, there is a lack of evidence demonstrating that task switching actually places additional demands on working memory. The present study addressed this issue by implementing task switching in continuous complex span tasks…

  12. Working Memory Costs of Task Switching

    ERIC Educational Resources Information Center

    Liefooghe, Baptist; Barrouillet, Pierre; Vandierendonck, Andre; Camos, Valerie

    2008-01-01

    Although many accounts of task switching emphasize the importance of working memory as a substantial source of the switch cost, there is a lack of evidence demonstrating that task switching actually places additional demands on working memory. The present study addressed this issue by implementing task switching in continuous complex span tasks…

  13. 14 CFR 29.1145 - Ignition switches.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Ignition switches. 29.1145 Section 29.1145... switches. (a) Ignition switches must control each ignition circuit on each engine. (b) There must be means to quickly shut off all ignition by the grouping of switches or by a master ignition control....

  14. 14 CFR 29.1145 - Ignition switches.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Ignition switches. 29.1145 Section 29.1145... switches. (a) Ignition switches must control each ignition circuit on each engine. (b) There must be means to quickly shut off all ignition by the grouping of switches or by a master ignition control....

  15. 14 CFR 29.1145 - Ignition switches.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Ignition switches. 29.1145 Section 29.1145... switches. (a) Ignition switches must control each ignition circuit on each engine. (b) There must be means to quickly shut off all ignition by the grouping of switches or by a master ignition control....

  16. 14 CFR 25.1145 - Ignition switches.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Ignition switches. 25.1145 Section 25.1145... switches. (a) Ignition switches must control each engine ignition circuit on each engine. (b) There must be means to quickly shut off all ignition by the grouping of switches or by a master ignition control....

  17. 14 CFR 25.1145 - Ignition switches.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Ignition switches. 25.1145 Section 25.1145... switches. (a) Ignition switches must control each engine ignition circuit on each engine. (b) There must be means to quickly shut off all ignition by the grouping of switches or by a master ignition control....

  18. Nonequilibrium Plasma Research

    DTIC Science & Technology

    2010-05-01

    Unfiltered Image Sequences of the Plasma Jet and CDBD Emission Acquired with a 5 ns Gated ICCD Camera. (b) Normalized Intensity from Displacement Current...measurements. A 15-ns-rise-time high-voltage stacked MOSFET switch was used to apply 6 kV to the electrodes for pulse durations of 250 ns at a 100- Hz...streamers were recorded using an intensified CCD camera. The camera gate was set to 20 ns and delayed with respect to the overvoltage peak by 20-ns

  19. Electronic logic for enhanced switch reliability

    DOEpatents

    Cooper, J.A.

    1984-01-20

    A logic circuit is used to enhance redundant switch reliability. Two or more switches are monitored for logical high or low output. The output for the logic circuit produces a redundant and fail-safe representation of the switch outputs. When both switch outputs are high, the output is high. Similarly, when both switch outputs are low, the logic circuit's output is low. When the output states of the two switches do not agree, the circuit resolves the conflict by memorizing the last output state which both switches were simultaneously in and produces the logical complement of this output state. Thus, the logic circuit of the present invention allows the redundant switches to be treated as if they were in parallel when the switches are open and as if they were in series when the switches are closed. A failsafe system having maximum reliability is thereby produced.

  20. PLASMA GENERATOR

    DOEpatents

    Foster, J.S. Jr.

    1958-03-11

    This patent describes apparatus for producing an electricity neutral ionized gas discharge, termed a plasma, substantially free from contamination with neutral gas particles. The plasma generator of the present invention comprises a plasma chamber wherein gas introduced into the chamber is ionized by a radiofrequency source. A magnetic field is used to focus the plasma in line with an exit. This magnetic field cooperates with a differential pressure created across the exit to draw a uniform and uncontaminated plasma from the plasma chamber.

  1. Terahertz emission from collapsing field domains during switching of a gallium arsenide bipolar transistor.

    PubMed

    Vainshtein, Sergey; Kostamovaara, Juha; Yuferev, Valentin; Knap, Wojciech; Fatimy, Abdel; Diakonova, Nina

    2007-10-26

    Broadband pulsed THz emission with peak power in the sub-mW range has been observed experimentally during avalanche switching in a gallium arsenide bipolar junction transistor at room temperature, while significantly higher total generated power is predicted in simulations. The emission is attributed to very fast oscillations in the conductivity current across the switching channels, which appear as a result of temporal evolution of the field domains generated in highly dense electron-hole plasma. This plasma is formed in turn by powerful impact ionization in multiple field domains of ultrahigh amplitude.

  2. Design and Prototype of an Automated Column-Switching HPLC System for Radiometabolite Analysis.

    PubMed

    Vasdev, Neil; Collier, Thomas Lee

    2016-08-17

    Column-switching high performance liquid chromatography (HPLC) is extensively used for the critical analysis of radiolabeled ligands and their metabolites in plasma. However, the lack of streamlined apparatus and consequently varying protocols remain as a challenge among positron emission tomography laboratories. We report here the prototype apparatus and implementation of a fully automated and simplified column-switching procedure to allow for the easy and automated determination of radioligands and their metabolites in up to 5 mL of plasma. The system has been used with conventional UV and coincidence radiation detectors, as well as with a single quadrupole mass spectrometer.

  3. Design and Prototype of an Automated Column-Switching HPLC System for Radiometabolite Analysis

    PubMed Central

    Vasdev, Neil; Collier, Thomas Lee

    2016-01-01

    Column-switching high performance liquid chromatography (HPLC) is extensively used for the critical analysis of radiolabeled ligands and their metabolites in plasma. However, the lack of streamlined apparatus and consequently varying protocols remain as a challenge among positron emission tomography laboratories. We report here the prototype apparatus and implementation of a fully automated and simplified column-switching procedure to allow for the easy and automated determination of radioligands and their metabolites in up to 5 mL of plasma. The system has been used with conventional UV and coincidence radiation detectors, as well as with a single quadrupole mass spectrometer. PMID:27548189

  4. Non-latching relay switch assembly

    DOEpatents

    Duimstra, Frederick A.

    1991-01-01

    A non-latching relay switch assembly which includes a coil section and a switch or contact section. The coil section includes a permanent magnet and an electromagnet. The respective sections are arranged in separate locations or cavities in the assembly. The switch has a "normal" position and is selectively switched by an overriding electromagnetic assembly. The switch returns to the "normal" position when the overriding electromagnetic assembly is inactive.

  5. High speed packet switching

    NASA Technical Reports Server (NTRS)

    1991-01-01

    This document constitutes the final report prepared by Proteon, Inc. of Westborough, Massachusetts under contract NAS 5-30629 entitled High-Speed Packet Switching (SBIR 87-1, Phase 2) prepared for NASA-Greenbelt, Maryland. The primary goal of this research project is to use the results of the SBIR Phase 1 effort to develop a sound, expandable hardware and software router architecture capable of forwarding 25,000 packets per second through the router and passing 300 megabits per second on the router's internal busses. The work being delivered under this contract received its funding from three different sources: the SNIPE/RIG contract (Contract Number F30602-89-C-0014, CDRL Sequence Number A002), the SBIR contract, and Proteon. The SNIPE/RIG and SBIR contracts had many overlapping requirements, which allowed the research done under SNIPE/RIG to be applied to SBIR. Proteon funded all of the work to develop new router interfaces other than FDDI, in addition to funding the productization of the router itself. The router being delivered under SBIR will be a fully product-quality machine. The work done during this contract produced many significant findings and results, summarized here and explained in detail in later sections of this report. The SNIPE/RIG contract was completed. That contract had many overlapping requirements with the SBIR contract, and resulted in the successful demonstration and delivery of a high speed router. The development that took place during the SNIPE/RIG contract produced findings that included the choice of processor and an understanding of the issues surrounding inter processor communications in a multiprocessor environment. Many significant speed enhancements to the router software were made during that time. Under the SBIR contract (and with help from Proteon-funded work), it was found that a single processor router achieved a throughput significantly higher than originally anticipated. For this reason, a single processor router was

  6. Resistive Switching of Plasma–Treated Zinc Oxide Nanowires for Resistive Random Access Memory

    PubMed Central

    Lai, Yunfeng; Qiu, Wenbiao; Zeng, Zecun; Cheng, Shuying; Yu, Jinling; Zheng, Qiao

    2016-01-01

    ZnO nanowires (NWs) were grown on Si(100) substrates at 975 °C by a vapor-liquid-solid method with ~2 nm and ~4 nm gold thin films as catalysts, followed by an argon plasma treatment for the as-grown ZnO NWs. A single ZnO NW–based memory cell with a Ti/ZnO/Ti structure was then fabricated to investigate the effects of plasma treatment on the resistive switching. The plasma treatment improves the homogeneity and reproducibility of the resistive switching of the ZnO NWs, and it also reduces the switching (set and reset) voltages with less fluctuations, which would be associated with the increased density of oxygen vacancies to facilitate the resistive switching as well as to average out the stochastic movement of individual oxygen vacancies. Additionally, a single ZnO NW–based memory cell with self-rectification could also be obtained, if the inhomogeneous plasma treatment is applied to the two Ti/ZnO contacts. The plasma-induced oxygen vacancy disabling the rectification capability at one of the Ti/ZnO contacts is believed to be responsible for the self-rectification in the memory cell.

  7. High power solid state switches

    NASA Astrophysics Data System (ADS)

    Gundersen, Martin

    1991-11-01

    We have successfully produced an optically triggered thyristor based in Gallium Arsenide, developed a model for breakdown, and are developing two related devices, including a Gallium Arsenide based static inductor thyristor. We are getting at the basic limitations of Gallium Arsenide for these applications, and are developing models for the physical processes that will determine device limitations. The previously supported gas phase work - resulting in the back-lighted thyratron (BLT) - has actually resulted in a very changed view of how switching can be accomplished, and this is impacting the design of important machines. The BLT is being studied internationally: in Japan for laser fusion and laser isotope separation. ITT has built a BLT that has switched 30 kA at 60 kV in testing at NSWC Dahlgren and the device is being commercialized by another American company. Versions of the switch are now being tested for excimer laser and other applications. Basically, the switch, which arose from pulse power physics studies at USC, can switch more current faster (higher di/dt), with less housekeeping, and with other advantageous properties. There are a large number of other new applications, include kinetic energy weapons, pulsed microwave sources and R.F. accelerators.

  8. Wide Bandgap Extrinsic Photoconductive Switches

    NASA Astrophysics Data System (ADS)

    Sullivan, James Stephen

    Wide Bandgap Extrinsic Photoconductive Switches Semi-insulating Gallium Nitride, 4H and 6H Silicon Carbide are attractive materials for compact, high voltage, extrinsic, photoconductive switches due to their wide bandgap, high dark resistance, high critical electric field strength and high electron saturation velocity. These wide bandgap semiconductors are made semi-insulating by the addition of vanadium (4H and 6H-SiC) and iron (2H-GaN) impurities that form deep acceptors. These deep acceptors trap electrons donated from shallow donor impurities. The electrons can be optically excited from these deep acceptor levels into the conduction band to transition the wide bandgap semiconductor materials from a semi-insulating to a conducting state. Extrinsic photoconductive switches with opposing electrodes have been constructed using vanadium compensated 6H-SiC and iron compensated 2H-GaN. These extrinsic photoconductive switches were tested at high voltage and high power to determine if they could be successfully used as the closing switch in compact medical accelerators. The successful development of a vanadium compensated, 6H-SiC extrinsic photoconductive switch for use as a closing switch for compact accelerator applications was realized by improvements made to the vanadium, nitrogen and boron impurity densities. The changes made to the impurity densities were based on the physical intuition outlined and simple rate equation models. The final 6H-SiC impurity 'recipe' calls for vanadium, nitrogen and boron densities of 2.5 e17 cm-3, 1.25e17 cm-3 and ≤ 1e16 cm-3, respectively. This recipe was originally developed to maximize the quantum efficiency of the vanadium compensated 6H-SiC, while maintaining a thermally stable semi-insulating material. The rate equation models indicate that, besides increasing the quantum efficiency, the impurity recipe should be expected to also increase the carrier recombination time. Three generations of 6H-SiC materials were tested. The

  9. Photoresistance switching of plasmonic nanopores.

    PubMed

    Li, Yi; Nicoli, Francesca; Chen, Chang; Lagae, Liesbet; Groeseneken, Guido; Stakenborg, Tim; Zandbergen, Henny W; Dekker, Cees; Van Dorpe, Pol; Jonsson, Magnus P

    2015-01-14

    Fast and reversible modulation of ion flow through nanosized apertures is important for many nanofluidic applications, including sensing and separation systems. Here, we present the first demonstration of a reversible plasmon-controlled nanofluidic valve. We show that plasmonic nanopores (solid-state nanopores integrated with metal nanocavities) can be used as a fluidic switch upon optical excitation. We systematically investigate the effects of laser illumination of single plasmonic nanopores and experimentally demonstrate photoresistance switching where fluidic transport and ion flow are switched on or off. This is manifested as a large (∼ 1-2 orders of magnitude) increase in the ionic nanopore resistance and an accompanying current rectification upon illumination at high laser powers (tens of milliwatts). At lower laser powers, the resistance decreases monotonically with increasing power, followed by an abrupt transition to high resistances at a certain threshold power. A similar rapid transition, although at a lower threshold power, is observed when the power is instead swept from high to low power. This hysteretic behavior is found to be dependent on the rate of the power sweep. The photoresistance switching effect is attributed to plasmon-induced formation and growth of nanobubbles that reversibly block the ionic current through the nanopore from one side of the membrane. This explanation is corroborated by finite-element simulations of a nanobubble in the nanopore that show the switching and the rectification.

  10. HOLLOTRON switch for megawatt lightweight space inverters

    NASA Technical Reports Server (NTRS)

    Poeschel, R. L.; Goebel, D. M.; Schumacher, R. W.

    1991-01-01

    The feasibility of satisfying the switching requirements for a megawatt ultralight inverter system using HOLLOTRON switch technology was determined. The existing experimental switch hardware was modified to investigate a coaxial HOLLOTRON switch configuration and the results were compared with those obtained for a modified linear HOLLOTRON configuration. It was concluded that scaling the HOLLOTRON switch to the current and voltage specifications required for a megawatt converter system is indeed feasible using a modified linear configuration. The experimental HOLLOTRON switch operated at parameters comparable to the scaled coaxial HOLLOTRON. However, the linear HOLLOTRON data verified the capability for meeting all the design objectives simultaneously including current density (greater than 2 A/sq cm), voltage (5 kV), switching frequency (20 kHz), switching time (300 ns), and forward voltage drop (less than or equal to 20 V). Scaling relations were determined and a preliminary design was completed for an engineering model linear HOLLOTRON switch to meet the megawatt converter system specifications.

  11. Adaptive optical label packet switching

    NASA Astrophysics Data System (ADS)

    Xiao, Shilin; Liu, Zhixin; Liang, Zheng; Zhao, Zhihui; Qu, Kefeng

    2007-11-01

    This paper introduces a kind of Adaptive Optical Label Packet Switching (AOLPS) technology. Based on Optical Packet Switching (OPS), AOLPS uses optical label to achieve self-routing, and the size of optical packet is self-adaptive. At the edge nodes, IP packets are fist classified into different first-in-fist-out memories (FIFOs) according to their priority levels and destinations, and then being encapsulated into optical packets. The traffic at each FIFO is real-time monitored, and the controller in edge node employs an optimal strategy to generate suitable sized packets for transmission. Large sized packets will be adopted when traffic is heavy, and small sized packets will be used when traffic is light. This self-adaptive switching granularity can greatly improve the network performance.

  12. Cross-switched MICRAD seeker

    NASA Astrophysics Data System (ADS)

    Alpers, Frederick C.; Hoover, Mervyn C.

    1992-11-01

    A MICrowave RADiometric (MICRAD) guidance system is disclosed which utilizes an antenna having four beams. The beams are designated right, left, up, and down. Information from the four beams is monitored essentially 100 percent of the time by passing through appropriate ferrite cross-switching means to four separate receivers. Information from two of the receivers passes through a first multiplexer and feedback gain balancer to provide a target azimuth output, and information from the remaining two receivers passes through a second multiplexer and feedback gain balancer to provide a target elevation output. A local oscillator heterodynes each of the four receivers in common, and a switch driver couples each of the multiplexers to the ferrite cross-switching means and gain balancers for appropriate selection.

  13. Finite-time quantised feedback asynchronously switched control of sampled-data switched linear systems

    NASA Astrophysics Data System (ADS)

    Wang, Ronghao; Xing, Jianchun; Li, Juelong; Xiang, Zhengrong

    2016-10-01

    This paper studies the problem of stabilising a sampled-data switched linear system by quantised feedback asynchronously switched controllers. The idea of a quantised feedback asynchronously switched control strategy originates in earlier work reflecting actual system characteristic of switching and quantising, respectively. A quantised scheme is designed depending on switching time using dynamic quantiser. When sampling time, system switching time and controller switching time are all not uniform, the proposed switching controllers guarantee the system to be finite-time stable by a piecewise Lyapunov function and the average dwell-time method. Simulation examples are provided to show the effectiveness of the developed results.

  14. Predicting conformational switches in proteins.

    PubMed Central

    Young, M.; Kirshenbaum, K.; Dill, K. A.; Highsmith, S.

    1999-01-01

    We describe a new computational technique to predict conformationally switching elements in proteins from their amino acid sequences. The method, called ASP (Ambivalent Structure Predictor), analyzes results from a secondary structure prediction algorithm to identify regions of conformational ambivalence. ASP identifies ambivalent regions in 16 test protein sequences for which function involves substantial backbone rearrangements. In the test set, all sites previously described as conformational switches are correctly predicted to be structurally ambivalent regions. No such regions are predicted in three negative control protein sequences. ASP may be useful as a guide for experimental studies on protein function and motion in the absence of detailed three-dimensional structural data. PMID:10493576

  15. A piezoelectric cryogenic heat switch.

    PubMed

    Jahromi, Amir E; Sullivan, Dan F

    2014-06-01

    We have measured the thermal conductance of a mechanical heat switch actuated by a piezoelectric positioner, the PZHS (PieZo electric Heat Switch), at cryogenic temperatures. The thermal conductance of the PZHS was measured between 4 K and 10 K, and on/off conductance ratios of about 100-200 at lowest and highest measures temperature were achieved when the positioner applied its maximum force of 8 N, respectively. We discuss the advantages of using this system in cryogenic applications, and estimate the ultimate performance of an ideal PZHS.

  16. Optical switch using Risley prisms

    DOEpatents

    Sweatt, William C.; Christenson, Todd R.

    2003-04-15

    An optical switch using Risley prisms and rotary microactuators to independently rotate the wedge prisms of each Risley prism pair is disclosed. The optical switch comprises an array of input Risley prism pairs that selectively redirect light beams from a plurality of input ports to an array of output Risley prism pairs that similarly direct the light beams to a plurality of output ports. Each wedge prism of each Risley prism pair can be independently rotated by a variable-reluctance stepping rotary microactuator that is fabricated by a multi-layer LIGA process. Each wedge prism can be formed integral to the annular rotor of the rotary microactuator by a DXRL process.

  17. Optical Switch Using Risley Prisms

    DOEpatents

    Sweatt, William C.; Christenson, Todd R.

    2005-02-22

    An optical switch using Risley prisms and rotary microactuators to independently rotate the wedge prisms of each Risley prism pair is disclosed. The optical switch comprises an array of input Risley prism pairs that selectively redirect light beams from a plurality of input ports to an array of output Risley prism pairs that similarly direct the light beams to a plurality of output ports. Each wedge prism of each Risley prism pair can be independently rotated by a variable-reluctance stepping rotary microactuator that is fabricated by a multi-layer LIGA process. Each wedge prism can be formed integral to the annular rotor of the rotary microactuator by a DXRL process.

  18. Switch Using Radio Frequency Identification

    NASA Technical Reports Server (NTRS)

    Fink, Patrick W. (Inventor); Lin, Gregory Y. (Inventor); Kennedy, Timothy F. (Inventor); Ngo, Phong H. (Inventor)

    2015-01-01

    Disclosed is an apparatus for use as a switch. In one embodiment, the switch comprises at least one RFID tag, each RFID tag comprising an antenna element and an RFID integrated circuit, at least one source element, and at least one lever arm. Each lever arm is connected to one of the RFID tags, and each lever arm is capable of two positions. One of the positions places the lever arm and the RFID tag connected thereto into alignment with the source element. Other embodiments are also described.

  19. Bumpless switching control for switched systems with partial actuator failures

    NASA Astrophysics Data System (ADS)

    Qi, Yiwen; Bao, Wen; Zhang, Qingxin; Chang, Juntao

    2016-11-01

    This study is concerned with the bumpless transfer problem for switched systems with partial actuator failures, in order to obtain smooth system performance output transition. Taking into account that the system requires a controller switching from current sub-controller to a fault-tolerant sub-controller after actuator fault. And bumpless transfer for control input cannot be traditionally designed when the actuator fault occurs, while performance smoothing can be considered and it is actually the ultimate goal of bumpless transfer. Specifically, the actuator fault model is firstly established and partial actuator fault is considered. Then, the system performance output signal is deemed as the main design variable of bumpless transfer, and closed-loop control systems both previous and after controller switching are constructed. Moreover, by using model matching thought and the adaptive sliding mode control technique, a bumpless transfer compensator design strategy is given to drive the performance output variable (after controller switching) to track the one of reference model. At last, simulation results of numeric and application examples demonstrate the effectiveness of the proposed bumpless transfer strategy.

  20. Surface flashover threshold and switched fields of photoconductive semiconductor switches

    SciTech Connect

    Loubriel, G.M.; O'Malley, M.W.; Zutavern, F.J.; McKenzie, B.B.; Conley, W.R.

    1988-01-01

    We have shown that Si Photoconductive Semiconductor Switches (PCSS) can be used to switch high voltages (up to 123 kV), high fields (up to 82 kV/cm) and high currents (2.8 kA). The ability of the samples to withstand this type of high voltage, high current switching depends on the way in which the current penetrates the semiconductor. The appropriate use of water or contacts greatly improves the switching capability. We have also shown that the wafers can support large currents (4.0 kA for GaAs and 2.8 kA for Si) and large linear current densities (3.2 kA/cm for GaAs and 1.4 kA/cm for Si). For GaAs this linear current density corresponds to about 1 Ma/cm/sup 2/ given a penetration depth of about 10/sup /minus/3/ cm. 4 refs., 4 figs., 2 tabs.

  1. System for automatically switching transformer coupled lines

    NASA Technical Reports Server (NTRS)

    Dwinell, W. S. (Inventor)

    1979-01-01

    A system is presented for automatically controlling transformer coupled alternating current electric lines. The secondary winding of each transformer is provided with a center tap. A switching circuit is connected to the center taps of a pair of secondary windings and includes a switch controller. An impedance is connected between the center taps of the opposite pair of secondary windings. The switching circuit has continuity when the AC lines are continuous and discontinuity with any disconnect of the AC lines. Normally open switching means are provided in at least one AC line. The switch controller automatically opens the switching means when the AC lines become separated.

  2. Molecular DNA switches and DNA chips

    NASA Astrophysics Data System (ADS)

    Sabanayagam, Chandran R.; Berkey, Cristin; Lavi, Uri; Cantor, Charles R.; Smith, Cassandra L.

    1999-06-01

    We present an assay to detect single-nucleotide polymorphisms on a chip using molecular DNA switches and isothermal rolling- circle amplification. The basic principle behind the switch is an allele-specific oligonucleotide circularization, mediated by DNA ligase. A DNA switch is closed when perfect hybridization between the probe oligonucleotide and target DNA allows ligase to covalently circularize the probe. Mismatches around the ligation site prevent probe circularization, resulting in an open switch. DNA polymerase is then used to preferentially amplify the closed switches, via rolling-circle amplification. The stringency of the molecular switches yields 102 - 103 fold discrimination between matched and mismatched sequences.

  3. Design and Development of a Series Switch for High Voltage in RF Heating

    NASA Astrophysics Data System (ADS)

    Patel, Himanshu K.; Shah, Deep; Thacker, Mauli; Shah, Atman

    2013-02-01

    Plasma is the fourth state of matter. To sustain plasma in its ionic form very high temperature is essential. RF heating systems are used to provide the required temperature. Arching phenomenon in these systems can cause enormous damage to the RF tube. Heavy current flows across the anode-cathode junction, which need to be suppressed in minimal time for its protection. Fast-switching circuit breakers are used to cut-off the load from the supply in cases of arching. The crowbar interrupts the connection between the high voltage power supply (HVPS) and the RF tube for a temporary period between which the series switch has to open. The crowbar shunts the current across the load but in the process leads to short circuiting the HVPS. Thus, to protect the load as well as the HVPS a series switch is necessary. This paper presents the design and development of high voltage Series Switch for the high power switching applications. Fiber optic based Optimum triggering scheme is designed and tested to restrict the time delay well within the stipulated limits. The design is well supported with the experimental results for the whole set-up along with the series switch at various voltage level before its approval for operation at 5.2 kV.

  4. Pre-switching bifurcation of a slender jet

    NASA Astrophysics Data System (ADS)

    Audier, P.; Sciamarella, D.; Artana, G.

    2016-01-01

    In this work, we study the near-field of the jet flow exiting a slot-model with aspect ratio 7.5:1. The core of the slender jet separates into two streams which subsequently merge recomposing a single core jet. Axis switching occurs downstream following self-similarity rules. In order to unveil the 3D dynamics of this pre-switching bifurcation, stereo-PIV (Particle Image Velocimetry) measurements are performed and a phase-locking technique is implemented using surface dielectric barrier discharge plasma actuators. The device forces the flow with low-amplitude localized disturbances to produce a lock-on phenomenon. The symmetric modes of the Crow instability, developing between the counter-rotating vortex tubes formed at the slot exit, are found to account for the bifurcation process.

  5. Experimental investigation of plasma relaxation using a compact coaxial magnetized plasma gun in a background plasma

    NASA Astrophysics Data System (ADS)

    Zhang, Yue; Lynn, Alan; Gilmore, Mark; Hsu, Scott; University of New Mexico Collaboration; Los Alamos National Laboratory Collaboration

    2013-10-01

    A compact coaxial plasma gun is employed for experimental studies of plasma relaxation in a low density background plasma. Experiments are being conducted in the linear HelCat device at UNM. These studies will advance the knowledge of basic plasma physics in the areas of magnetic relaxation and space and astrophysical plasmas, including the evolution of active galactic jets/radio lobes within the intergalactic medium. The gun is powered by a 120pF ignitron-switched capacitor bank which is operated in a range of 5-10 kV and ~100 kA. Multiple diagnostics are employed to investigate plasma relaxation process. Magnetized Argon plasma bubbles with velocities ~1.2Cs and densities ~1020 m-3 have been achieved. Different distinct regimes of operation with qualitatively different dynamics are identified by fast CCD camera images, with the parameter determining the operation regime. Additionally, a B-dot probe array is employed to measure the spatial toroidal and poloidal magnetic flux evolution to identify detached plasma bubble configurations. Experimental data and analysis will be presented.

  6. Switching processes in financial markets

    PubMed Central

    Preis, Tobias; Schneider, Johannes J.; Stanley, H. Eugene

    2011-01-01

    For an intriguing variety of switching processes in nature, the underlying complex system abruptly changes from one state to another in a highly discontinuous fashion. Financial market fluctuations are characterized by many abrupt switchings creating upward trends and downward trends, on time scales ranging from macroscopic trends persisting for hundreds of days to microscopic trends persisting for a few minutes. The question arises whether these ubiquitous switching processes have quantifiable features independent of the time horizon studied. We find striking scale-free behavior of the transaction volume after each switching. Our findings can be interpreted as being consistent with time-dependent collective behavior of financial market participants. We test the possible universality of our result by performing a parallel analysis of fluctuations in time intervals between transactions. We suggest that the well known catastrophic bubbles that occur on large time scales—such as the most recent financial crisis—may not be outliers but single dramatic representatives caused by the formation of increasing and decreasing trends on time scales varying over nine orders of magnitude from very large down to very small. PMID:21521789

  7. Fast all-optical switch

    NASA Technical Reports Server (NTRS)

    Shay, Thomas M. (Inventor); Poliakov, Evgeni Y. (Inventor); Hazzard, David A. (Inventor)

    2001-01-01

    An apparatus and method wherein polarization rotation in alkali vapors or other mediums is used for all-optical switching and digital logic and where the rate of operation is proportional to the amplitude of the pump field. High rates of speed are accomplished by Rabi flopping of the atomic states using a continuously operating monochromatic atomic beam as the pump.

  8. High voltage MOSFET switching circuit

    DOEpatents

    McEwan, Thomas E.

    1994-01-01

    The problem of source lead inductance in a MOSFET switching circuit is compensated for by adding an inductor to the gate circuit. The gate circuit inductor produces an inductive spike which counters the source lead inductive drop to produce a rectangular drive voltage waveform at the internal gate-source terminals of the MOSFET.

  9. Anode initiated surface flashover switch

    SciTech Connect

    Brainard, John P.; Koss, Robert J.

    2003-04-29

    A high voltage surface flashover switch has a pair of electrodes spaced by an insulator. A high voltage is applied to an anode, which is smaller than the opposing, grounded, cathode. When a controllable source of electrons near the cathode is energized, the electrons are attracted to the anode where they reflect to the insulator and initiate anode to cathode breakdown.

  10. Magnetically Insulated Opening Switch Research.

    DTIC Science & Technology

    1987-01-01

    this research is to investigate the validity of the magneti- cally insulated opening switch concept proposed by Eninger (Ref. 5, Appendix 1). The...1973). 3. Y. Carmel, and J. Nation, Phys, Rev. Lett. 31, 286 (1973). 4. T.J. Orzechowski, and G. Bekefi, Phys. Fluids 19, 43 (1976). U 5. 3. Eninger

  11. High voltage MOSFET switching circuit

    DOEpatents

    McEwan, T.E.

    1994-07-26

    The problem of source lead inductance in a MOSFET switching circuit is compensated for by adding an inductor to the gate circuit. The gate circuit inductor produces an inductive spike which counters the source lead inductive drop to produce a rectangular drive voltage waveform at the internal gate-source terminals of the MOSFET. 2 figs.

  12. Optimal path to epigenetic switching

    NASA Astrophysics Data System (ADS)

    Roma, David Marin; O'Flanagan, Ruadhan A.; Ruckenstein, Andrei E.; Sengupta, Anirvan M.; Mukhopadhyay, Ranjan

    2005-01-01

    We use large deviation methods to calculate rates of noise-induced transitions between states in multistable genetic networks. We analyze a synthetic biochemical circuit, the toggle switch, and compare the results to those obtained from a numerical solution of the master equation.

  13. Focusing, Sustaining, and Switching Attention

    DTIC Science & Technology

    2013-09-12

    task-irrelevant sound features strongly enhances the ability to maintain attention on a stream based on some other, orthogonal feature, and 3...visual cues can be used to direct selective auditory attention. 15. SUBJECT TERMS selective attention, streaming, grouping, sound segregation, auditory...sustaining, and switching attention A. Scientific and Technical Objectives Acoustic information is conveyed by changes in sound over time

  14. Switching mechanism senses angular acceleration

    NASA Technical Reports Server (NTRS)

    1966-01-01

    Switching mechanism actuates an electrical circuit when a predetermined angular acceleration and displacement are reached. A rotor in the mechanism overcomes the restraint of a magnetic detent when the case in which the detent is mounted reaches the predetermined angular acceleration.

  15. Remotely-actuated biomedical switch

    NASA Technical Reports Server (NTRS)

    Lee, R. D.

    1969-01-01

    Remotely-actuated biomedical switching circuit using transistors consumes no power in the off position and can be actuated by a single-frequency telemetry pulse to control implanted instrumentation. Silicon controlled rectifiers permit the circuit design which imposes zero drain on supply batteries when not in use.

  16. Wide Bandgap Extrinsic Photoconductive Switches

    SciTech Connect

    Sullivan, James S.

    2013-07-03

    Semi-insulating Gallium Nitride, 4H and 6H Silicon Carbide are attractive materials for compact, high voltage, extrinsic, photoconductive switches due to their wide bandgap, high dark resistance, high critical electric field strength and high electron saturation velocity. These wide bandgap semiconductors are made semi-insulating by the addition of vanadium (4H and 6HSiC) and iron (2H-GaN) impurities that form deep acceptors. These deep acceptors trap electrons donated from shallow donor impurities. The electrons can be optically excited from these deep acceptor levels into the conduction band to transition the wide bandgap semiconductor materials from a semi-insulating to a conducting state. Extrinsic photoconductive switches with opposing electrodes have been constructed using vanadium compensated 6H-SiC and iron compensated 2H-GaN. These extrinsic photoconductive switches were tested at high voltage and high power to determine if they could be successfully used as the closing switch in compact medical accelerators.

  17. Cosmic plasma

    NASA Technical Reports Server (NTRS)

    Alfven, H.

    1981-01-01

    Attention is given to experimental and theoretical approaches to plasma physics, plasma phenomena in laboratory and space, field and particle aspects of plasmas, the present state of the classical theory, boundary conditions and circuit dependence, and cosmology. Electric currents in space plasmas are considered, taking into account dualism in physics, particle-related phenomena in plasma physics, magnetic field lines, filaments, local plasma properties and the circuit, electric double layers, field-aligned currents as 'cables', an expanding circuit, different types of plasma regions, the cellular structure of space, and the fine structure of active plasma regions. Other topics discussed are related to circuits, the theory of cosmic plasmas, the origin of the solar system, the coexistence of matter and antimatter, annihilation as a source of energy, the Hubble expansion in a Euclidean space, and a model for the evolution of the Metagalaxy.

  18. 30 CFR 75.1000 - Cutout switches.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Trolley Wires and Trolley Feeder Wires § 75.1000 Cutout switches. Trolley wires and trolley feeder wires, shall be provided with cutout switches at intervals of...

  19. Ultrafast Beam Switching Using Coupled VCSELs

    NASA Technical Reports Server (NTRS)

    Ning, Cun-Zheng; Goorjian, Peter

    2001-01-01

    We propose a new approach to performing ultrafast beam switching using two coupled Vertical-Cavity Surface-Emitting Lasers (VCSELs). The strategy is demonstrated by numerical simulation, showing a beam switching of 10 deg at 42 GHz.

  20. 30 CFR 75.1000 - Cutout switches.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Trolley Wires and Trolley Feeder Wires § 75.1000 Cutout switches. Trolley wires and trolley feeder wires, shall be provided with cutout switches at intervals...

  1. 30 CFR 75.1000 - Cutout switches.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Trolley Wires and Trolley Feeder Wires § 75.1000 Cutout switches. Trolley wires and trolley feeder wires, shall be provided with cutout switches at intervals...

  2. 30 CFR 75.1000 - Cutout switches.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Trolley Wires and Trolley Feeder Wires § 75.1000 Cutout switches. Trolley wires and trolley feeder wires, shall be provided with cutout switches at intervals...

  3. Efficient use of Q-switched lasers in the treatment of cutaneous lesions

    NASA Astrophysics Data System (ADS)

    Hu, Xin-Hua

    1995-05-01

    The use of Q-switched laser has been well documented in the treatment of pigmented lesions, particularly in the tattoo removal. To better understand the ablation process by Q-switched lasers, we carried out an analysis on the states and other physical properties of certain tissue/pigment under the action of a strong transient electric field associated with the high energy nanosecond laser pulses. The dependence of the ablation threshold of transient electric field on the chromophore absorption has been found to be weak. A plasma ablation model is used to interpret previous experimental results. The comparison of the plasma model with the conventional selective photothermolysis model has led to a new design concept of Q-switched lasers for dermatology surgery.

  4. Carbon isotope controlled molecular switches

    NASA Astrophysics Data System (ADS)

    Foster, Brian K.

    Single molecules represent one fundamental limit to the downscaling of electronics. As a prototype element for carbon-based nanoscale science and technology, the detailed behavior of carbon monoxide (CO) on the copper surface Cu(111) has been investigated. These investigations span from individual carbon isotope resolution, to single molecules, to compact clusters assembled by molecular manipulation via a homemade scanning tunneling microscope (STM). Sub-nanoscale devices, composed of only a few molecules, which exploit both lone CO properties and molecule-molecule interaction, have been designed and assembled. The devices function as bi-stable switches and can serve as classical bits with densities > 50 Tbits/cm2. Operated in the nuclear mass sensitive regime, each switch can also function as a molecular "centrifuge" capable of identifying the isotope of a single carbon atom in real-time. A model, based on electron-vibron couping and inelastic tunneling, has been developed and explains the dynamic behavior of the switch. The interaction between pairs of switches was also explored and it was found that their behavior ranges from completely independent to strongly coupled. Larger nanostructures, which were composed of many sub-switches organized to leverage the fully coupled interaction, link two spatially separated "bits" on the surface. Such a linked system can set or read a state non-locally, which is equivalent to bidirectional information transfer. The linked system has also exhibited logic functionality. These experiments demonstrate scalable molecular cells for information storage, and for information processing through cellular automata logic schemes.

  5. Low temperature grown GaNAsSb: A promising material for photoconductive switch application

    SciTech Connect

    Tan, K. H.; Yoon, S. F.; Wicaksono, S.; Loke, W. K.; Li, D. S.; Saadsaoud, N.; Tripon-Canseliet, C.; Lampin, J. F.; Decoster, D.; Chazelas, J.

    2013-09-09

    We report a photoconductive switch using low temperature grown GaNAsSb as the active material. The GaNAsSb layer was grown at 200 °C by molecular beam epitaxy in conjunction with a radio frequency plasma-assisted nitrogen source and a valved antimony cracker source. The low temperature growth of the GaNAsSb layer increased the dark resistivity of the switch and shortened the carrier lifetime. The switch exhibited a dark resistivity of 10{sup 7} Ω cm, a photo-absorption of up to 2.1 μm, and a carrier lifetime of ∼1.3 ps. These results strongly support the suitability of low temperature grown GaNAsSb in the photoconductive switch application.

  6. Spark gap switch with spiral gas flow

    DOEpatents

    Brucker, John P.

    1989-01-01

    A spark gap switch having a contaminate removal system using an injected gas. An annular plate concentric with an electrode of the switch defines flow paths for the injected gas which form a strong spiral flow of the gas in the housing which is effective to remove contaminates from the switch surfaces. The gas along with the contaminates is exhausted from the housing through one of the ends of the switch.

  7. A new very high voltage semiconductor switch

    NASA Technical Reports Server (NTRS)

    Sundberg, G. R.

    1985-01-01

    A new family of semiconductor switches using double injection techniques and compensated deep impurities is described. They have the potential to raise switching voltages a factor of 10 higher (up to 100 kV) than p-n junction devices while exhibiting extremely low (or zero) forward voltage. Several potential power switching applications are indicated.

  8. 46 CFR 112.43-1 - Switches.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Switches. 112.43-1 Section 112.43-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Lighting Systems § 112.43-1 Switches. An emergency lighting system must not have a switch, except...

  9. 46 CFR 112.43-1 - Switches.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Switches. 112.43-1 Section 112.43-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Lighting Systems § 112.43-1 Switches. An emergency lighting system must not have a switch, except...

  10. 46 CFR 112.43-1 - Switches.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Switches. 112.43-1 Section 112.43-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Lighting Systems § 112.43-1 Switches. An emergency lighting system must not have a switch, except...

  11. 46 CFR 112.43-1 - Switches.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Switches. 112.43-1 Section 112.43-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Lighting Systems § 112.43-1 Switches. An emergency lighting system must not have a switch, except...

  12. 46 CFR 112.43-1 - Switches.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Switches. 112.43-1 Section 112.43-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Lighting Systems § 112.43-1 Switches. An emergency lighting system must not have a switch, except...

  13. Switch for serial or parallel communication networks

    DOEpatents

    Crosette, Dario B.

    1994-01-01

    A communication switch apparatus and a method for use in a geographically extensive serial, parallel or hybrid communication network linking a multi-processor or parallel processing system has a very low software processing overhead in order to accommodate random burst of high density data. Associated with each processor is a communication switch. A data source and a data destination, a sensor suite or robot for example, may also be associated with a switch. The configuration of the switches in the network are coordinated through a master processor node and depends on the operational phase of the multi-processor network: data acquisition, data processing, and data exchange. The master processor node passes information on the state to be assumed by each switch to the processor node associated with the switch. The processor node then operates a series of multi-state switches internal to each communication switch. The communication switch does not parse and interpret communication protocol and message routing information. During a data acquisition phase, the communication switch couples sensors producing data to the processor node associated with the switch, to a downlink destination on the communications network, or to both. It also may couple an uplink data source to its processor node. During the data exchange phase, the switch couples its processor node or an uplink data source to a downlink destination (which may include a processor node or a robot), or couples an uplink source to its processor node and its processor node to a downlink destination.

  14. Photoconductive switching for high power microwave generation

    SciTech Connect

    Pocha, M.D.; Hofer, W.W.

    1990-10-01

    Photoconductive switching is a technology that is being increasingly applied to generation of high power microwaves. Two primary semiconductors used for these devices are silicon and gallium arsenide. Diamond is a promising future candidate material. This paper discusses the important material parameters and switching modes, critical issues for microwave generation, and future directions for this high power, photoconductive switching technology.

  15. 14 CFR 27.1361 - Master switch.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... STANDARDS: NORMAL CATEGORY ROTORCRAFT Equipment Electrical Systems and Equipment § 27.1361 Master switch. (a) There must be a master switch arrangement to allow ready disconnection of each electric power source from the main bus. The point of disconnection must be adjacent to the sources controlled by the switch...

  16. A CW Gunn Diode Switching Element.

    ERIC Educational Resources Information Center

    Hurtado, Marco; Rosenbaum, Fred J.

    As part of a study of the application of communication satellites to educational development, certain technical aspects of such a system were examined. A current controlled bistable switching element using a CW Gunn diode is reported on here. With modest circuits switching rates of the order of 10 MHz have been obtained. Switching is initiated by…

  17. 14 CFR 27.1361 - Master switch.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Master switch. 27.1361 Section 27.1361... STANDARDS: NORMAL CATEGORY ROTORCRAFT Equipment Electrical Systems and Equipment § 27.1361 Master switch. (a) There must be a master switch arrangement to allow ready disconnection of each electric power...

  18. 14 CFR 27.1367 - Switches.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Switches. 27.1367 Section 27.1367... STANDARDS: NORMAL CATEGORY ROTORCRAFT Equipment Electrical Systems and Equipment § 27.1367 Switches. Each switch must be— (a) Able to carry its rated current; (b) Accessible to the crew; and (c) Labeled as...

  19. 49 CFR 236.821 - Switch, sectionalizing.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Switch, sectionalizing. 236.821 Section 236.821 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... Switch, sectionalizing. A switch for disconnecting a section of a power line from the source of energy....

  20. 46 CFR 111.105-19 - Switches.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Switches. 111.105-19 Section 111.105-19 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Hazardous Locations § 111.105-19 Switches. A switch that is explosionproof or flameproof, or...