Sample records for plesiotherapy
-
Use of strontium-90 plesiotherapy for the treatment of a lingual plasmacytoma in a dog.
Ware, K; Gieger, T
2011-04-01
A 12-year-old, 25 kg, intact male St Bernard crossbreed was presented for treatment of a 538 mm ulcerated tumour on the dorsal tongue. Fine-needle aspiration cytology revealed a plasmacytoma. The dog staged negative for evidence of local metastatic or systemic disease. Histopathology confirmed the diagnosis. Treatment with one 150 Gy dose of radiation delivered with strontium-90 plesiotherapy was performed. Side effects were not noted and there was no visible evidence of tumour remaining at 2 months and 1 year after therapy. © 2011 British Small Animal Veterinary Association.
-
Donaldson, D; Sansom, J; Murphy, S; Scase, T
2006-09-01
An eight-year-old, neutered, male border collie dog was presented with a six-week history of left ocular discomfort and a raised, red mass at the lateral limbus. The right eye had been enucleated approximately 12 months previously following suspected trauma when the eye had become red and painful. The mass was excised using superficial keratectomy/sclerectomy and the surgery site was treated with strontium-90 beta radiation. Histopathological findings were consistent with a diagnosis of haemangiosarcoma. Immunohistochemical staining showed uniform expression of CD31 in neoplastic cells, confirming their endothelial origin. Two further treatments with strontium-90 beta radiation were applied to the surgical site at weekly intervals. Twenty-six weeks after surgery, a second, raised, red limbal mass became apparent at the medial limbus of the left eye. Surgical excision and adjuvant strontium-90 beta plesiotherapy were performed as described for the initial tumour. Routine histopathological analysis confirmed haemangiosarcoma at this site. Eighty-six weeks following the initial presentation, no recurrence of ocular haemangiosarcoma was evident.
-
Diagnosis and treatment of a periocular myxosarcoma in a bearded dragon (Pogona vitticeps).
Gardhouse, Sara; Eshar, David; Lee-Chow, Bridget; Foster, Robert A; Ingrao, Joelle C; Poirier, Valerie J
2014-07-01
A 5-year-old male Australian bearded dragon (Pogona vitticeps) was presented with a 2-month history of a periocular mass. The clinical evaluation included a physical examination, hematology, biochemistry, and radiographs. The mass was treated surgically and diagnosed as myxosarcoma. Strontium-90 plesiotherapy was attempted, but the mass recurred 5 mo later.
-
Diagnosis and treatment of a periocular myxosarcoma in a bearded dragon (Pogona vitticeps)
Gardhouse, Sara; Eshar, David; Lee-Chow, Bridget; Foster, Robert A.; Ingrao, Joelle C.; Poirier, Valerie J.
2014-01-01
A 5-year-old male Australian bearded dragon (Pogona vitticeps) was presented with a 2-month history of a periocular mass. The clinical evaluation included a physical examination, hematology, biochemistry, and radiographs. The mass was treated surgically and diagnosed as myxosarcoma. Strontium-90 plesiotherapy was attempted, but the mass recurred 5 mo later. PMID:24982518
-
Nevile, Jessica C; Hurn, Simon D; Turner, Andrew G; McCowan, Christina
2015-05-01
To report three cases of canine corneal squamous cell carcinoma (SCC) treated with strontium 90 beta radiation as an adjunct to surgical excision. Corneal SCC was excised with lamellar keratectomy. This was followed by local application of strontium 90 beta radiation. Available case follow-up times range from 3 to 50 months. One case suffered a recurrence 5 months following initial excision and strontium 90 treatment. Strontium 90 beta radiation has been used extensively as an adjunctive treatment for equine corneal SCC and in other canine ocular tumors; however, there is a paucity of information regarding use in canine corneal SCC. The cases presented here suggest its use following keratectomy may be helpful in preventing disease recurrence. At the dosage used, severe adverse effects were not observed. © 2014 American College of Veterinary Ophthalmologists.
-
Contemporary role of radiotherapy in the management of penile cancer
Korzeniowski, Martin Arthur
2017-01-01
Penile cancer is a rare clinical entity that contributes to significant patient morbidity and mortality. Human papilloma virus (HPV) plays an important role in the carcinogenesis of penile squamous cell carcinoma (SCC), is associated with improved clinical outcomes, and is predictive for response to treatment with chemotherapy and radiotherapy. Historically, treatment consisted of radical surgery with partial or total penectomy. While effective for local control, surgical resection can impart significant physical, psychological and sexual dysfunction for afflicted men. Organ preservation strategies offer significant quality of life advantages over standard surgery and can be utilized without compromising oncological control. As an alternative or adjunct to surgical resection, radiation therapy can be used for organ preservation strategies successfully in up to 70% of patients. A variety of treatment techniques can be employed depending on the location and burden of disease. Limited disease can be amenable to treatment with interstitial brachytherapy, surface mold plesiotherapy or external beam radiotherapy. For locally advanced presentations, or for patients not amenable to surgical resection, excellent clinical outcomes can be achieved using a combination of chemotherapy and radiation therapy. Here, we discuss the management of penile SCC using modern radiation therapy treatment techniques, the expected clinical outcomes for organ preservation, as well as the management of side-effects and toxicities. While large randomized trials are being developed, the management of penile cancer is informed from the management of other of other anogenital malignancies, which we also review. PMID:29184783