Sample records for pm panel study

  1. EXPOSURE ASSESSMENT FROM THE NERL RESEARCH TRIANGLE PARK PARTICULATE MATTER PANEL STUDY

    EPA Science Inventory

    The U.S. Environmental Protection Agency performed a particulate matter (PM) exposure assessment based on data from the National Exposure Research Laboratory (NERL) Research Triangle Park (RTP) Particulate Matter (PM) Panel Study. This study was a one-year investigation of PM ...

  2. MASS CONCENTRATION RELATIONSHIPS FROM THE NERL RTP PARTICULATE MATTER PANEL STUDY

    EPA Science Inventory

    The National Exposure Research Laboratory's (NERL) Research Triangle Park (RTP) Particulate Matter (PM) Panel Study has completed a one-year investigation of personal, residential and ambient PM-related mass concentrations in two potentially susceptible subpopulations. PM2.5, P...

  3. PARTICIPANT RECRUITMENT AND RETENTION FOR THE NERL RTP PM PANEL STUDY

    EPA Science Inventory

    EPA's National Exposure Research Laboratory (NERL) completed a 12 month Particulate Matter (PM) Panel Study in the Research Triangle Park, NC area in May 2001. A primary goal of the study was to compare PM levels measured at an ambient and residential sites with those from per...

  4. The Effect of Economic Growth, Urbanization, and Industrialization on Fine Particulate Matter (PM2.5) Concentrations in China.

    PubMed

    Li, Guangdong; Fang, Chuanglin; Wang, Shaojian; Sun, Siao

    2016-11-01

    Rapid economic growth, industrialization, and urbanization in China have led to extremely severe air pollution that causes increasing negative effects on human health, visibility, and climate change. However, the influence mechanisms of these anthropogenic factors on fine particulate matter (PM 2.5 ) concentrations are poorly understood. In this study, we combined panel data and econometric methods to investigate the main anthropogenic factors that contribute to increasing PM 2.5 concentrations in China at the prefecture level from 1999 to 2011. The results showed that PM 2.5 concentrations and three anthropogenic factors were cointegrated. The panel Fully Modified Least Squares and panel Granger causality test results indicated that economic growth, industrialization, and urbanization increased PM 2.5 concentrations in the long run. The results implied that if China persists in its current development pattern, economic growth, industrialization and urbanization will inevitably lead to increased PM 2.5 emissions in the long term. Industrialization was the principal factor that affected PM 2.5 concentrations for the total panel, the industry-oriented panel and the service-oriented panel. PM 2.5 concentrations can be reduced at the cost of short-term economic growth and industrialization. However, reducing the urbanization level is not an efficient way to decrease PM 2.5 pollutions in the short term. The findings also suggest that a rapid reduction of PM 2.5 concentrations relying solely on adjusting these anthropogenic factors is difficult in a short-term for the heavily PM 2.5 -polluted panel. Moreover, the Chinese government will have to seek much broader policies that favor a decoupling of these coupling relationships.

  5. THE RESEARCH TRIANGLE PARK PARTICULATE MATTER PANEL STUDY: MODELING AMBIENT SOURCE CONTRIBUTION TO PERSONAL AND RESIDENTIAL PM MASS CONCENTRATIONS

    EPA Science Inventory

    The Research Triangle Park (RTP) Particulate Matter (PM) Panel Study represented a one-year investigation of personal, residential and ambient PM mass concentrations across distances as large as 70 km in central North Carolina. One of the primary goals of this effort was to est...

  6. PRELIMINARY FINDINGS FROM THE NERL RESEARCH TRIANGLE PARK PARTICULATE MATTER PANEL STUDY

    EPA Science Inventory

    The U.S. Environmental Protection Agency is currently conducting the National Exposure Research Laboratory (NERL) Research Triangle Park (RTP) Particulate Matter (PM) Panel Study. This study represents a one year investigation of PM and related co-pollutants involving two dist...

  7. PARTICLE SIZE DISTRIBUTIONS FROM SELECT RESIDENCES PARTICIPATING IN THE NERL RTP PM PANEL STUDY

    EPA Science Inventory

    Particle Size Distributions from Select Residences Participating in the NERL RTP PM Panel Study. Alan Vette, Ronald Williams, and Michael Riediker, U.S. Environmental Protection Agency, National Exposure Research Laboratory, Research Triangle Park, NC 27711; Jonathan Thornburg...

  8. 76 FR 10039 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-23

    ... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel; Chronic Pelvic Pain Clinical Study. Date... Digestive and Kidney Diseases Special Emphasis Panel; Ulcerative Colitis Clinical Trials. Date: March 29... Diseases Special Emphasis Panel; Urology Clinical Trials. Date: March 30, 2011. Time: 2:30 p.m. to 3:30 p.m...

  9. THE RESEARCH TRIANGLE PARK PARTICULATE MATTER PANEL STUDY: PM MASS CONCENTRATION RELATIONSHIPS

    EPA Science Inventory

    The U.S. Environmental Protection Agency has recently performed the Research Triangle Park Particulate Matter Panel Study. This was a one-year investigation of PM and related co-pollutants involving participants living within the RTP area of North Carolina. Primary goals were t...

  10. GASEOUS CO-POLLUTANTS ASSOCIATED WITH PARTICULATE MATTER-RESULTS FROM THE NERL RTP PM PANEL STUDY

    EPA Science Inventory

    The U.S. EPA National Exposure Research Laboratory (NERL) conducted a longitudinal particulate matter (PM) panel study in Research Triangle Park, NC between June 2000 and June 2001. Participants were selected from two potentially susceptible sub-populations: a multi-racial grou...

  11. PRELIMINARY PARTICULATE MATTER MASS CONCENTRATIONS ASSOCIATED WITH LONGITUDINAL PANEL STUDIES "ASSESSING HUMAN EXPOSURES OF HIGH RISK SUBPOPULATIONS TO PARTICULATE MATTER"

    EPA Science Inventory

    The NERL Particulate Matter Longitudinal Panel Studies were used to characterize temporal variations of personal exposure to PM and related co-pollutants, including that of PM measured at ambient sites. These studies were fundamental in understanding the associations between p...

  12. A bacterial bioreporter panel to assay the cytotoxicity of atmospheric particulate matter

    NASA Astrophysics Data System (ADS)

    Kessler, Nivi; Schauer, James J.; Yagur-Kroll, Sharon; Melamed, Sahar; Tirosh, Ofir; Belkin, Shimshon; Erel, Yigal

    2012-12-01

    Numerous studies have demonstrated that elevated concentrations of suspended atmospheric particulate matter (PM) are associated with adverse health effects. In order to minimize the adverse public health effects of atmospheric PM by exposure management, there is a need for a greater understanding of the toxic mechanisms and the components that are responsible for the toxic effects. The aim of this study was to utilize bioassay techniques to investigate these aspects. For this purpose a reporter panel of 9 genetically engineered bacterial (Escherichia coli) strains was composed. Each panel member was designed to report on a different stress condition with a measurable light signal produced by the luciferase enzyme. Toxic mechanisms and components were studied using six anthropogenic PM source samples, including two vehicle combustion particles, three coal fly ash (CFA) samples and an urban dust sample. The most prominent outcome of the panel exposure results were broad panel responses observed for two of the CFA samples, indicating oxidative stress, respiration inhibition and iron deficiency. These responses were relieved when the samples were treated with EDTA, a non-specific metal chelator, suggesting the involvement of metals in the observed effects. Bioavailability analysis of the samples suggests that chromium was related to the toxic responses induced by two of the CFA samples. Oxidative stress was also observed in several samples of ambient atmospheric aerosols and excess metal toxicity in an urban dust sample collected in a parking lot. The reporter panel approach, as demonstrated in this study, has the potential of providing novel insights as to the mechanisms of atmospheric PM toxicity. Furthermore, combining the panel's results with bioavailability data can enlighten about the role of different PM components in the observed toxicity.

  13. 78 FR 12769 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-25

    ... Pathogenesis Study Section. Date: March 18, 2013. Time: 8:00 a.m. to 5:00 p.m. Agenda: To review and evaluate... Young Adulthood. Date: March 18, 2013. Time: 3:00 p.m. to 4:00 p.m. Agenda: To review and evaluate grant... Panel; RFA Panel: CounterACT U54 Centers of Excellence. Date: March 19, 2013. Time: 8:00 a.m. to 12:00 p...

  14. OUTDOOR VS. HUMAN EXPOSURE: NERL PM EXPOSURE PANEL STUDIES

    EPA Science Inventory

    An association has been demonstrated between ambient particulate matter (PM 2.5 and PM 10) concentrations and human morbidity/mortality. However, little is known regarding the most important sources of PM exposure, interpersonal and intrapersonal variability in exposure, and the...

  15. 78 FR 40486 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-05

    ... Institute of Child Health and Human Development Special Emphasis Panel, ZHD1 DRG-D 42 1. Date: July 10, 2013... Panel, ZHD1 DRG-D 41 1. Date: July 16, 2013. Time: 2:00 p.m. to 5:00 p.m. Agenda: To review and evaluate... Development Special Emphasis Panel, ZHD1 DRG-D 43 1. Date: August 1, 2013. Time: 2:00 p.m. to 5:00 p.m. Agenda...

  16. AMBIENT PARTICULATE MATTER EXPOSURES: A COMPARISON OF SHEDS-PM EXPOSURE MODEL PREDICTIONS AND ESTIMATES DERIVED FROM MEASUREMENTS COLLECTED DURING NERL'S RTP PM PANEL STUDY

    EPA Science Inventory

    The US EPA National Exposure Research Laboratory (NERL) is currently refining and evaluating a population exposure model for particulate matter (PM), called the Stochastic Human Exposure and Dose Simulation (SHEDS-PM) model. The SHEDS-PM model estimates the population distribu...

  17. Modeling individual exposures to ambient PM2.5 in the diabetes and the environment panel study (DEPS)

    EPA Science Inventory

    Air pollution epidemiology studies of ambient fine particulate matter (PM2.5) often use outdoor concentrations as exposure surrogates, which can induce exposure error. The goal of this study was to improve ambient PM2.5 exposure assessments for a repeated measurements study with ...

  18. 75 FR 59728 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-28

    ... Panel; Member Conflict: Arthritis, Connective Tissue and Skin Special Emphasis Panel. Date: November 17... Panel; Stem Cells in Cancer. Date: November 1, 2010. Time: 1 p.m. to 4 p.m. Agenda: To review and...

  19. 76 FR 47218 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-04

    ... Panel, Member Conflicts: Liver Pathobiology and Pharmacology. Date: August 30, 2011. Time: 1 p.m. to 4 p... Emphasis Panel, Member Conflict: Cancer Prevention. Date: September 8, 2011. Time: 1 p.m. to 4 p.m. Agenda...

  20. 77 FR 21788 - Center for Scientific Review Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-11

    ... Development, Stem Cell and Myocardial Regeneration. Date: May 10, 2012. Time: 2 p.m. to 3:30 p.m. Agenda: To... for Scientific Review Special Emphasis Panel; RFA Panel: Single Cell Analysis Reviews. Date: May 8... for Scientific Review Special Emphasis Panel; RFA Panel: Single Cell Analysis Reviews. Date: May 9...

  1. 75 FR 20007 - Proposal Review Panel for Chemistry; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-16

    ... NATIONAL SCIENCE FOUNDATION Proposal Review Panel for Chemistry; Notice of Meeting In accordance... California Institute of Technology by NSF Division of Chemistry (1191). Dates & Times: May 9, 2010; 8 p.m.-9 p.m., May 10, 2010; 8 a.m.- 9 p.m., May 11, 2010; 8 a.m.-1 p.m. Place: Department of Chemistry...

  2. PM2.5 EXPOSURE CHANGES HEART RATE VARIABILITY (HRV) AND BLOOD PARAMETERS IN STATE HIGHWAY PATROL TROOPERS

    EPA Science Inventory

    Epidemiological studies show an association between ambient particulate matter PM and cardiovascular mortality. Panel and controlled exposure studies report PM-associated changes in HRV and blood factors involved in clotting and inflammation. We investigated the effects of in-veh...

  3. POWER ANALYSIS OF LINEAR RELATIONSHIPS BETWEEN PERSONAL EXPOSURE AND INDOOR/OUTDOOR PM 2.5 CONCENTRATIONS AT BALTIMORE AND FRESNO

    EPA Science Inventory

    The National Exposure Research Laboratory is currently in the process of conducting panel studies to investigate personal exposure to particulate matter(PM). One of the primary goals of PM exposure studies is to establish mathematical relationships between personal exposure and...

  4. 77 FR 58146 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-19

    ... Emphasis Panel; RFA Panel: System Science and Health in the Behavioral and Social Sciences. Date: October... Special Emphasis Panel; Member Conflict: CMIP and MEDI. Date: October 19, 2012. Time: 1 p.m. to 4:30 p.m...

  5. 78 FR 69701 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-20

    ... Panel; PAR 13-061: Tuberculosis. Date: December 13, 2013. Time: 10:00 a.m. to 6:30 p.m. Agenda: To... Emphasis Panel; Tuberculosis. Date: December 13, 2013. Time: 3:30 p.m. to 5:00 p.m. Agenda: To review and...

  6. 78 FR 38354 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-26

    ...; Member Conflict: Psychological Health, Development and Aging. Date: July 22, 2013. Time: 2:30 p.m. to 4... Obesity. Date: July 24, 2013. Time: 10:00 a.m. to 12:00 p.m. Agenda: To review and evaluate grant... Emphasis Panel; PAR Panel: Biodemography of Aging. Date: July 24, 2013. Time: 12:30 p.m. to 4:30 p.m...

  7. 76 FR 63625 - Center for Scientific Review Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-13

    ...: Diabetes and Nutrition. Date: November 8, 2011. Time: 12 p.m. to 6 p.m. Agenda: To review and evaluate... Disorders and Neuropathies Special Emphasis Panel. Date: October 26, 2011. Time: 2 p.m. to 4 p.m. Agenda: To... Special Emphasis Panel; Small Business: Radiation Therapy and Biology. Date: November 1-2, 2011. Time: 9 a...

  8. PM CONCENTRATIONS ASSOCIATED WITH PERSONAL ACTIVITIES BASED ON REAL-TIME PERSONAL NEPHELOMETRY DATA FROM THE NERL RTP PM PANEL STUDY

    EPA Science Inventory

    A longitudinal particulate matter (PM) exposure study sponsored by EPA's National Exposure Research Laboratory (NERL) was conducted in the Research Triangle Park, NC area between June 2000 and June 2001. Participants were selected from two groups of potentially susceptible sub-...

  9. 77 FR 2766 - Arts Advisory Panel Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-19

    ... NATIONAL FOUNDATION ON THE ARTS AND THE HUMANITIES Arts Advisory Panel Meeting AGENCY: National Endowment for the Arts, National Foundation on the Arts and Humanities. ACTION: Notice--additional... Media Arts panel, scheduled for January 26, 2012 from 3 p.m. to 4:30 p.m. This open session will be...

  10. 76 FR 60933 - Proposal Review Panel for Human Resource Development; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-30

    ... NATIONAL SCIENCE FOUNDATION Proposal Review Panel for Human Resource Development; Notice of..., Proposal Review Panel Human Resource Development ( 1199). Date/Time: October 17, 2011; 5 p.m. to 10 p.m... Meeting: Part-Open. Contact Person: Kelly Mack, Division of Human Resource Development, Room 815, National...

  11. 76 FR 60934 - Proposal Review Panel for Human Resource Development; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-30

    ... NATIONAL SCIENCE FOUNDATION Proposal Review Panel for Human Resource Development; Notice of...; Proposal Review Panel Human Resource Development ( 1199). Date/Time: November 1, 2011; 5 p.m. to 10 p.m...: Part-Open. Contact Person: Kelly Mack, Division of Human Resource Development, Room 815, National...

  12. 78 FR 21960 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-12

    ... and Alzheimer's Disease. Date: June 12, 2013. Time: 11 a.m. to 2 p.m. Agenda: To review and evaluate... Special Emphasis Panel; Alzheimer's Disease Prevention. Date: July 11, 2013. Time: 1 p.m. to 4 p.m. Agenda... of Committee: National Institute on Aging Special Emphasis Panel; Alzheimer's Disease Prevention...

  13. 76 FR 63315 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-12

    ... . Name of Committee: Center for Scientific Review Special Emphasis Panel, Drug Discovery for the Nervous System II. Date: November 2, 2011. Time: 1 p.m. to 3 p.m. Agenda: To review and evaluate grant... Panel, Small Business: Visual Systems. Date: November 3-4, 2011. Time: 8 a.m. to 5 p.m. Agenda: To...

  14. 77 FR 15113 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-14

    ... Emphasis Panel; Member Conflict: Integrative Neuroscience. Date: March 28, 2012. Time: 1 p.m. to 3 p.m... Emphasis Panel; Member Conflict: Biobehavioral Regulation, Learning and Ethology. Date: April 4, 2012. Time...

  15. 76 FR 59413 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-26

    ... personal privacy. Name of Committee: Center for Scientific Review Special Emphasis Panel, Hypertension and... Panel, Member Conflict: Gastrointestinal Pathophysiology. Date: October 20, 2011. Time: 12 p.m. to 3 p.m...

  16. 76 FR 24921 - Proposal Review Panel for Chemistry; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-03

    ... NATIONAL SCIENCE FOUNDATION Proposal Review Panel for Chemistry; Notice of Meeting In accordance... announces the following meeting: Name: Proposal Review Panel for Chemistry, 1191. Date and Time: May 12, 2011, 8:30 a.m.-5 p.m.; May 13, 2011, 8:30 a.m.-2 p.m. Place: Center for Chemistry at the Space-Time...

  17. 75 FR 65639 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-26

    ...: Computational Biology Special Emphasis Panel A. Date: October 29, 2010. Time: 2 p.m. to 3:30 p.m. Agenda: To.... Name of Committee: Center for Scientific Review Special Emphasis Panel; Member Conflict: Computational...

  18. 78 FR 16860 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-19

    ... Panel; Program Project: A Proteomics Research Center for Integrative Biology. Date: April 8-10, 2013... Special Emphasis Panel; Member Conflict: Cancer Biology. Date: April 11, 2013. Time: 2:00 p.m. to 4:30 p.m...

  19. 77 FR 29677 - National Institute on Aging Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-18

    ..., [email protected] . Name of Committee: National Institute on Aging Special Emphasis Panel; Alzheimer's Disease Study. Date: July 3, 2012. Time: 12:00 p.m. to 5:00 p.m. Agenda: To review and evaluate grant...

  20. 78 FR 20119 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-03

    ...: AIDS and AIDS Related Research. Date: April 23-24, 2013. Time: 10:00 a.m. to 5:00 p.m. Agenda: To... Special Emphasis Panel; PAR Panel: SIDS and BRAIN. Date: April 24, 2013. Time: 1:00 p.m. to 4:00 p.m... Assistance Program Nos. 93.306, Comparative Medicine; 93.333, Clinical Research, 93.306, 93.333, 93.337, 93...

  1. SUMMARY FINDINGS FROM THE U.S. EPA'S PARTICULATE MATTER PANEL STUDIES

    EPA Science Inventory

    The U.S. EPA's Particulate Matter Panel Studies were a series of longitudinal human exposure studies used to characterize personal exposures to particulate matter (PM) and related co-pollutants to that of pollutants of ambient origin. Participants were monitored over time (28 d...

  2. 77 FR 52337 - Eunice Kennedy Shriver National Institute of Child Health & Human Development Notice of Closed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-29

    ... Institute of Child Health and Human Development Special Emphasis Panel; Contraceptive Clinical Trials Network (Male Studies) September. Date: September 27, 2012. Time: 2 p.m. to 4 p.m. Agenda: To review and...

  3. 78 FR 11212 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-15

    ... Integrated Review Group; AIDS Molecular and Cellular Biology Study Section. Date: March 11, 2013. Time: 8:00... Panel; Member Conflict: Cancer Biology. Date: March 11, 2013. Time: 1:00 p.m. to 2:00 p.m. Agenda: To...

  4. REAL-TIME PERSONAL NEPHELOMETER AND TIME ACTIVITY DATA FROM THE NERL RTP PM PANEL STUDY

    EPA Science Inventory

    A longitudinal particulate matter (PM) exposure study was conducted in the Research Triangle Park, NC, area between June 2000 and June 2001. Participants were selected from two groups of potentially susceptible sub-populations: a group of African-Americans living in an environm...

  5. THE ROLE OF SUBPOPULATION, DISEASE STATE, HOUSING, SEASON AND OTHER FACTORS UPON PERSONAL EXPOSURES TO PM OF AMBIENT ORIGIN

    EPA Science Inventory

    A series of longitudinal particulate matter (PM) and related co-pollutant human exposure panel field studies have recently been completed. Studies were conducted in Baltimore, Maryland (1997,1998) Fresno, California (1999) and Research Triangle Park, North Carolina (2002-2001)...

  6. AN OVERVIEW OF EPA'S HUMAN EXPOSURE PANEL STUDIES

    EPA Science Inventory

    In July 1997, the EPA Administrator issued new PM NAAQS that added PM2.5. The new standard is based largely on recent epidemiological investigations that indicated increased risks of mortality and morbidity are associated with higher concentrations of ambient particles. The new...

  7. 75 FR 8977 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-26

    ... Panel; Translational Diabetes and Obesity. Date: March 16-17, 2010. Time: 8 a.m. to 5 p.m. Agenda: To... Special Emphasis Panel; UKGD Member Conflict SEP. Date: March 25, 2010. Time: 11 a.m. to 1 p.m. Agenda: To...

  8. 78 FR 14098 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-04

    ... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel; Ancillary Studies to the Intestinal Stem Cells Consortium. Date: April 4, 2013. Time: 1:00 p.m. to 2:30 p.m. Agenda: To review and evaluate grant...

  9. 77 FR 5034 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-01

    ... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel, PAR-09-247 Ancillary Studies: Bariatric Surgery. Date: March 8, 2012. Time: 3 p.m. to 4:30 p.m. Agenda: To review and evaluate grant applications...

  10. THE INFLUENCE OF PARTICULATE MATTER OF AMBIENT ORIGIN UPON INDOOR RESIDENTIAL MASS CONCENTRATIONS INVOLVING SENSITIVE SUBPOPULATIONS-RESULTS FROM LONGITUDINAL PANEL STUDIES

    EPA Science Inventory

    The US EPA has completed field data collections from a series of longitudinal particulate matter (PM) exposure panel field studies. These studies were conducted in Baltimore, Maryland (1998), Fresno, California (1999), and Research Triangle Park (RTP), North Carolina (2000-2001) ...

  11. PERSONAL PARTICULATE MATTER EXPOSURE MONITORING: IDENTIFYING IMPORTANT SOURCES, ACTIVITIES, AND LOCATIONS BASED ON DATA FROM THE NERL RTP PM PANEL STUDY

    EPA Science Inventory

    A longitudinal particulate matter (PM) exposure study was conducted in the Research Triangle Park, NC area between June 2000 and June 2001. Participants were selected from two groups of potentially susceptible sub-populations: a group of African-Americans living in an environme...

  12. USE OF A CONTINUOUS NEPHELOMETER TO MEASURE PERSONAL EXPOSURE TO PARTICLES DURING THE U.S. EPA BALTIMORE AND FRESNO PANEL STUDIES

    EPA Science Inventory

    In population exposure studies, personal exposure to particulate matter (PM) is typically measured as a 12- to 24-hour integrated mass concentration. To better understand short-term variation in personal PM exposure, continuous (one-minute averaging time) nephelometers were wo...

  13. 76 FR 20720 - Advisory Panel for Integrative Activities; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-13

    ... Stimulate Competitive Research Science and Technology Centers (STC) 1373. Dates: May 16, 2011; 6 p.m.-8 p.m... NATIONAL SCIENCE FOUNDATION Advisory Panel for Integrative Activities; Notice of Meeting In accordance with the Federal Advisory Committee Act (Pub. L. 92- 463, as amended), the National Science...

  14. 76 FR 36555 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-22

    ... personal privacy. Name of Committee: Center for Scientific Review Special Emphasis Panel, Molecular Genetics. Date: July 6, 2011. Time: 2 p.m. to 4 p.m. Agenda: To review and evaluate grant applications... Committee: Center for Scientific Review Special Emphasis Panel, Statistical Genetics. Date: July 28, 2011...

  15. 76 FR 31619 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-01

    ... personal privacy. Name of Committee: Center for Scientific Review Special Emphasis Panel, Molecular Genetics Applications. Date: June 20, 2011. Time: 12:30 p.m. to 3 p.m. Agenda: To review and evaluate grant... Emphasis Panel, Small Business: Molecular, Cellular and Developmental Neurobiology. Date: June 30, 2011...

  16. 75 FR 11894 - Center For Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-12

    ... personal privacy. Name of Committee: Center for Scientific Review Special Emphasis Panel; Cancer Diagnostics and Therapeutics SBIR/STTR. Date: March 18, 2010. Time: 2 p.m. to 5 p.m. Agenda: To review and... of Committee: Center for Scientific Review Special Emphasis Panel; Member Conflict: Cancer Therapy...

  17. 76 FR 61722 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-05

    ... Institute Special Emphasis Panel, Data Coordinating Center for the Cardiovascular Cell Therapy Research... Special Emphasis Panel, Regional Clinical Center for the Cardiovascular Cell Therapy Research Network... Capture Agents for Cardiovascular Research. Date: October 24, 2011. Time: 1 p.m. to 3 p.m. Agenda: To...

  18. Modeling individual exposures to ambient PM2.5 in the diabetes and the environment panel study (DEPS).

    PubMed

    Breen, Michael; Xu, Yadong; Schneider, Alexandra; Williams, Ronald; Devlin, Robert

    2018-06-01

    Air pollution epidemiology studies of ambient fine particulate matter (PM 2.5 ) often use outdoor concentrations as exposure surrogates, which can induce exposure error. The goal of this study was to improve ambient PM 2.5 exposure assessments for a repeated measurements study with 22 diabetic individuals in central North Carolina called the Diabetes and Environment Panel Study (DEPS) by applying the Exposure Model for Individuals (EMI), which predicts five tiers of individual-level exposure metrics for ambient PM 2.5 using outdoor concentrations, questionnaires, weather, and time-location information. Using EMI, we linked a mechanistic air exchange rate (AER) model to a mass-balance PM 2.5 infiltration model to predict residential AER (Tier 1), infiltration factors (F inf_home , Tier 2), indoor concentrations (C in , Tier 3), personal exposure factors (F pex , Tier 4), and personal exposures (E, Tier 5) for ambient PM 2.5 . We applied EMI to predict daily PM 2.5 exposure metrics (Tiers 1-5) for 174 participant-days across the 13 months of DEPS. Individual model predictions were compared to a subset of daily measurements of F pex and E (Tiers 4-5) from the DEPS participants. Model-predicted F pex and E corresponded well to daily measurements with a median difference of 14% and 23%; respectively. Daily model predictions for all 174 days showed considerable temporal and house-to-house variability of AER, F inf_home , and C in (Tiers 1-3), and person-to-person variability of F pex and E (Tiers 4-5). Our study demonstrates the capability of predicting individual-level ambient PM 2.5 exposure metrics for an epidemiological study, in support of improving risk estimation. Copyright © 2018. Published by Elsevier B.V.

  19. The Research Triangle Park particulate matter panel study: PM mass concentration relationships

    NASA Astrophysics Data System (ADS)

    Williams, Ron; Suggs, Jack; Rea, Anne; Leovic, Kelly; Vette, Alan; Croghan, Carry; Sheldon, Linda; Rodes, Charles; Thornburg, Jonathan; Ejire, Ademola; Herbst, Margaret; Sanders, William

    The US Environmental Protection Agency has recently performed the Research Triangle Park Particulate Matter Panel Study. This was a 1-year investigation of PM and related co-pollutants involving participants living within the RTP area of North Carolina. Primary goals were to characterize the relationships between ambient and residential PM measures to those obtained from personal exposure monitoring and estimate ambient source contributions to personal and indoor mass concentrations. A total of 38 participants living in 37 homes were involved in personal, residential indoor, residential outdoor and ambient PM 2.5 exposure monitoring. Participants were 30 non-smoking hypertensive African-Americans living in a low-moderate SES neighborhood (SE Raleigh, NC) and a cohort of eight individuals having implanted cardiac defibrillators (Chapel Hill, NC). Residential and ambient monitoring of PM 10 and PM 10-2.5 (coarse by differential) was also performed. The volunteers were monitored for seven consecutive days during each of four seasons (summer 2000, fall 2000, winter 2001, spring 2001). Individual PM 2.5 personal exposure concentrations ranged from 4 to 218 μg m -3 during the study. The highest personal exposures were determined to be the result of passive environmental tobacco exposures. Subsequently, ˜7% of the total number of personal exposure trials were excluded to minimize this pollutant's effect upon the overall analysis. Results indicated that a pooled data set (seasons, cohorts, residences, participants) was appropriate for investigation of the basic mass concentration relationships. Daily personal PM 2.5 mass concentrations were typically higher than their associated residential or ambient measurements (mean personal=23.0, indoor=19.1, outdoor=19.3, ambient=19.2 μg m -3). Mean personal PM 2.5 exposures were observed to be only moderately correlated to ambient PM 2.5 concentrations ( r=0.39).

  20. 75 FR 16489 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-01

    ... Emphasis Panel; Adiposity, Aging, and Stem Cells. Date: June 23, 2010. Time: 1 p.m. to 5 p.m. Agenda: To... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Effect of Energy...

  1. 76 FR 40754 - Advisory Panel for Integrative Activities, #1373; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-11

    ... NATIONAL SCIENCE FOUNDATION Advisory Panel for Integrative Activities, 1373; Notice of Meeting In accordance with the Federal Advisory Committee Act (Pub. L. 92- 463, as amended), the National Science... (MRPAC). Date/Time: July 28, 2011 12 p.m.-4 p.m., EDT. Place: National Science Foundation, 4201 Wilson...

  2. 77 FR 59200 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-26

    ... Panel; PAR 10-018: Accelerating the Pace of Drug Abuse Research Using Existing Epidemiology, Prevention, and Treatment Research Data. Date: October 24, 2012. Time: 2 p.m. to 4 p.m. Agenda: To review and...: Center for Scientific Review Special Emphasis Panel; PA:12-006: Academic Research Enhancement Award...

  3. 78 FR 40487 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-05

    ... Committee: Center for Scientific Review Special Emphasis Panel; Biomedical Technology Research Center: A Biomedical- Informatics Research Network for Big Data. Date: July 30-August 1, 2013. Time: 6:00 p.m. to 1:00... Scientific Review Special Emphasis Panel; Gene Therapy Member Conflicts. Date: July 30, 2013. Time: 3:00 p.m...

  4. 77 FR 8890 - National Institute of Mental Health; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-15

    ...: To review and evaluate grant applications. Place: National Institutes of Health, Neuroscience Center... Health, NIH, Neuroscience Center, 6001 Executive Blvd., Room 6140, MSC 9608, Bethesda, MD 20892-9608, 301... Emphasis Panel; Cognitive Neuroscience and Schizophrenia Panel. Date: March 1, 2012. Time: 1 p.m. to 4 p.m...

  5. 77 FR 24970 - National Institute of Mental Health; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-26

    ... Emphasis Panel; Fast Fail--Experimental Medicines Contracts--Mood and Anxiety Disorders. Date: May 22, 2012... Institute of Mental Health Special Emphasis Panel; Fast Fail--Experimental Medicines Contracts--Autism. Date...-- Psychotic Spectrum. Date: May 25, 2012. Time: 1 p.m. to 6 p.m. Agenda: To review and evaluate contract...

  6. 77 FR 62520 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-15

    ... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel; Ancillary Studies to Major Ongoing Clinical Research Studies. Date: November 14, 2012. Time: 3:00 p.m. to 4:30 p.m. Agenda: To review and... Assistance Program Nos. 93.847, Diabetes, Endocrinology and Metabolic Research; 93.848, Digestive Diseases...

  7. 76 FR 78286 - National Institute of Diabetes and Digestive and Kidney Diseases Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-16

    ... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel, PAR09-247: Ancillary Studies to the ongoing Clincal Research Studies on IBSOS. Date: January 26, 2012. Time: 2 p.m. to 3:30 p.m. Agenda: To... Assistance Program Nos. 93.847, Diabetes, Endocrinology and Metabolic Research; 93.848, Digestive Diseases...

  8. Proceedings of the SDIO/ONR Pulse Power Meeting 󈨞 (3rd) Held in Norfolk, Virginia on August 2-3, 1990

    DTIC Science & Technology

    1990-08-01

    Modulators", - ’ 6:30 pm Evening Dinner Cruise on the "American Rover’ I U I iii I I I I Friday August 3, 1990 Session III Panel Session I 9:00 am Panel ...Session WHAT ARE THE ACCOMPLISHMENTS TO I DATE? WHAT ARE THE GOALS FOR THE PULSE POWER RESEARCH? i Moderator Arthur Guenther Panel Members Garscadden...Mourou Gundersen Roy Kristiansen Rustan Kushner Schoenbach Lee 10:30 am Coffee Break 10:45 am Panel Session Continued I 12:00 pm Closing Remarks Gabriel

  9. 76 FR 55076 - Center for Scientific Review Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-06

    ... Special Emphasis Panel; Neurotechnology 2. Date: October 6, 2011. Time: 3 p.m. to 4 p.m. Agenda: To review... Instrumentation: Neurotechnology. Date: October 6, 2011. Time: 4 p.m. to 5 p.m. Agenda: To review and evaluate...

  10. 76 FR 9018 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Emerging...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-16

    ..., Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Emerging Infections Sentinel... with Section 10(a)(2) of the Federal Advisory Committee Act (Pub. L. 92-463), the Centers for Disease Control and Prevention (CDC), announces the aforementioned meeting: Times and Dates: 12 p.m.-2 p.m., March...

  11. 77 FR 55853 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-11

    ... Panel; Childhood Obesity Prevention. Date: October 10, 2012. Time: 1 p.m. to 2 p.m. Agenda: To review... Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings Pursuant to section 10(d) of the... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel; NIDDK DEM Fellowships Review. Date...

  12. 76 FR 2083 - Pacific Fishery Management Council; Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-12

    ... Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National..., February 7, 2011 and end at 5:30 p.m. or as necessary to complete business for the day. The Panel will... ending at 5:30 p.m. each day, or as necessary to complete business. The Panel will adjourn by noon on...

  13. 75 FR 26284 - National Endowment for the Arts; Arts Advisory Panel

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-11

    ... NATIONAL FOUNDATION ON THE ARTS AND THE HUMANITIES National Endowment for the Arts; Arts Advisory..., notice is hereby given that nine meetings of the Arts Advisory Panel to the National Council on the Arts... meeting, from 3 p.m. to 3:30 p.m. EDT, will be closed. Folk and Traditional Arts (application review...

  14. 77 FR 60706 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-04

    ... Network Analysis and Health. Date: November 1, 2012. Time: 8:00 a.m. to 5:00 p.m. Agenda: To review and... Panel, Small Business: Sensory Technologies. Date: November 1-2, 2012. Time: 8:00 a.m. to 5:00 p.m... . Name of Committee: Center for Scientific Review Special Emphasis Panel, Fellowships: Sensory and Motor...

  15. 77 FR 21592 - Proposal Review Panel for Materials Research; Notice of Meeting: Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-10

    ... 19362, column 3, line 3, please replace: ``7 p.m.-8:30p.m. Open-Poster Session'' with ``7 p.m.-10:30p.m. Open-Poster Session''. Dated: April 5, 2012. Susanne Bolton, Committee Management Officer. [FR Doc...

  16. Acute effects of PM2.5 on lung function parameters in schoolchildren in Nanjing, China: a panel study.

    PubMed

    Xu, Dandan; Zhang, Yi; Zhou, Lian; Li, Tiantian

    2018-03-17

    The association between exposure to ambient particulate matter (PM) and reduced lung function parameters has been reported in many works. However, few studies have been conducted in developing countries with high levels of air pollution like China, and little attention has been paid to the acute effects of short-term exposure to air pollution on lung function. The study design consisted of a panel comprising 86 children from the same school in Nanjing, China. Four measurements of lung function were performed. A mixed-effects regression model with study participant as a random effect was used to investigate the relationship between PM 2.5 and lung function. An increase in the current day, 1-day and 2-day moving average PM 2.5 concentration was associated with decreases in lung function indicators. The greatest effect of PM 2.5 on lung function was detected at 1-day moving average PM 2.5 exposure. An increase of 10 μg/m 3 in the 1-day moving average PM 2.5 concentration was associated with a 23.22 mL decrease (95% CI: 13.19, 33.25) in Forced Vital Capacity (FVC), a 18.93 mL decrease (95% CI: 9.34, 28.52) in 1-s Forced Expiratory Volume (FEV 1 ), a 29.38 mL/s decrease (95% CI: -0.40, 59.15) in Peak Expiratory Flow (PEF), and a 27.21 mL/s decrease (95% CI: 8.38, 46.04) in forced expiratory flow 25-75% (FEF 25-75% ). The effects of PM 2.5 on lung function had significant lag effects. After an air pollution event, the health effects last for several days and we still need to pay attention to health protection.

  17. 76 FR 29772 - National Human Genome Research Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-23

    ... Institute Special Emphasis Panel; ELSI-SEP. Date: June 21, 2011. Time: 8 a.m. to 5:30 p.m. Agenda: To review... Emphasis Panel; Data Analysis-SEP. Date: June 27, 2011. Time: 8 a.m. to 5:30 p.m. Agenda: To review and evaluate grant applications. Place: Courtyard Arlington Crystal City/Reagan National Airport, 2899...

  18. Particulate air pollution and panel studies in children: a systematic review

    PubMed Central

    Ward, D; Ayres, J

    2004-01-01

    Aims: To systematically review the results of such studies in children, estimate summary measures of effect, and investigate potential sources of heterogeneity. Methods: Studies were identified by searching electronic databases to June 2002, including those where outcomes and particulate level measurements were made at least daily for ⩾8 weeks, and analysed using an appropriate regression model. Study results were compared using forest plots, and fixed and random effects summary effect estimates obtained. Publication bias was considered using a funnel plot. Results: Twenty two studies were identified, all except two reporting PM10 (24 hour mean) >50 µg.m-3. Reported effects of PM10 on PEF were widely spread and smaller than those for PM2.5 (fixed effects summary: -0.012 v -0.063 l.min-1 per µg.m-3 rise). A similar pattern was evident for symptoms. Random effects models produced larger estimates. Overall, in between-study comparisons, panels of children with diagnosed asthma or pre-existing respiratory symptoms appeared less affected by PM10 levels than those without, and effect estimates were larger where studies were conducted in higher ozone conditions. Larger PM10 effect estimates were obtained from studies using generalised estimating equations to model autocorrelation and where results were derived by pooling subject specific regression coefficients. A funnel plot of PM10 results for PEF was markedly asymmetrical. Conclusions: The majority of identified studies indicate an adverse effect of particulate air pollution that is greater for PM2.5 than PM10. However, results show considerable heterogeneity and there is evidence consistent with publication bias, so limited confidence may be placed on summary estimates of effect. The possibility of interaction between particle and ozone effects merits further investigation, as does variability due to analytical differences that alter the interpretation of final estimates. PMID:15031404

  19. A panel study of airborne particulate matter concentration and impaired cardiopulmonary function in young adults by two different exposure measurement

    NASA Astrophysics Data System (ADS)

    Hu, Li-Wen; Qian, Zhengmin (Min); Bloom, Michael S.; Nelson, Erik J.; Liu, Echu; Han, Bin; Zhang, Nan; Liu, Yimin; Ma, Huimin; Chen, Duo-Hong; Yang, Bo-Yi; Zeng, Xiao-Wen; Chen, Wen; Komppula, Mika; Leskinen, Ari; Hirvonen, Maija-Riitta; Roponen, Marjut; Jalava, Pasi; Bai, Zhipeng; Dong, Guang-Hui

    2018-05-01

    This study sought to clarify the correlation of individual exposure measurements and PM2.5 measurements collected at regulatory monitoring sites in short-term panel study settings. To achieve this goal, 30 young, healthy adult participants were assigned to three groups with 4 samplers in each group to collect individual exposures during four weekends in March 2016. Participants also completed cardiopulmonary function tests during the same periods. For comparison, ambient air pollution data were obtained from the Air Pollution Surveillance Network in Guangzhou, China. The 8-h ambient pollutant averages and group sampler concentrations were used as separate indicators of air pollution exposure. Results showed that the 8-h mean concentration of personal PM2.5 exposure was 65.09 ± 22.18 μg/m3, which was 24.34 μg/m3 statistically higher than the ambient concentrations over the same period (p < 0.05). However, these concentrations were strongly correlated (Spearman's r = 0.937, p < 0.01). Separate mixed-effect models were fit for ambient and personal exposures to estimate their associations with cardiopulmonary outcomes. Higher PM2.5 and PM10 exposures were related to lower lung function of maximal mid-expiratory flow (MMEF). A 10 μg/m3 higher PM was associated with 0.11 L/S to 0.52 L/S lower MMEF. No effects on cardiovascular function were found. In conclusion, personal PM2.5 exposure might be higher than ambient concentrations. Young, healthy adults in urban areas may experience reduced lung function (lower MMEF), even after just 8 h of exposure to PM2.5 and PM10.

  20. 77 FR 65567 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-29

    ... for Scientific Review Special Emphasis Panel; PA-12-139: Pilot and Feasibility Clinical Research Studies in Digestive Diseases and Nutrition. Date: November 29, 2012. Time: 2:00 p.m. to 4:00 p.m. Agenda... Assistance Program Nos. 93.306, Comparative Medicine; 93.333, Clinical Research, 93.306, 93.333, 93.337, 93...

  1. SOURCE APPORTIONMENT OF INDOOR, OUTDOOR, AND PERSONAL PM2.5 IN SEATTLE, WASHINGTON, USING POSITIVE MATRIX FACTORIZATION

    EPA Science Inventory

    As part of a large exposure assessment and health effects panel study, 33 trace elements and light-absorbing carbon were measured on 24-hr particulate matter with an aero-dynamic diameter <2.5 um (PM2.5) fixed-site filter samples collected between September 26, 2000, and May 25, ...

  2. 75 FR 6674 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-10

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review... Scientific Review Special Emphasis Panel, Microvascular Interactions. Date: March 3, 2010. Time: 3 p.m. to 5... Social Consequences of HIV/AIDS Study Section. Date: March 15-16, 2010. Time: 8 a.m. to 5 p.m. Agenda: To...

  3. Heart rate variability and DNA methylation levels are altered after short-term metal fume exposure among occupational welders: a repeated-measures panel study.

    PubMed

    Fan, Tianteng; Fang, Shona C; Cavallari, Jennifer M; Barnett, Ian J; Wang, Zhaoxi; Su, Li; Byun, Hyang-Min; Lin, Xihong; Baccarelli, Andrea A; Christiani, David C

    2014-12-16

    In occupational settings, boilermakers are exposed to high levels of metallic fine particulate matter (PM2.5) generated during the welding process. The effect of welding PM2.5 on heart rate variability (HRV) has been described, but the relationship between PM2.5, DNA methylation, and HRV is not known. In this repeated-measures panel study, we recorded resting HRV and measured DNA methylation levels in transposable elements Alu and long interspersed nuclear element-1 (LINE-1) in peripheral blood leukocytes under ambient conditions (pre-shift) and right after a welding task (post-shift) among 66 welders. We also monitored personal PM2.5 level in the ambient environment and during the welding procedure. The concentration of welding PM2.5 was significantly higher than background levels in the union hall (0.43 mg/m3 vs. 0.11 mg/m3, p < 0.0001). The natural log of transformed power in the high frequency range (ln HF) had a significantly negative association with PM2.5 exposure (β = -0.76, p = 0.035). pNN10 and pNN20 also had a negative association with PM2.5 exposure (β = -0.16%, p = 0.006 and β = -0.13%, p = 0.030, respectively). PM2.5 was positively associated with LINE-1 methylation [β = 0.79%, 5-methylcytosince (%mC), p = 0.013]; adjusted for covariates. LINE-1 methylation did not show an independent association with HRV. Acute decline of HRV was observed following exposure to welding PM2.5 and evidence for an epigenetic response of transposable elements to short-term exposure to high-level metal-rich particulates was reported.

  4. 75 FR 11870 - Meeting of the Ocean Research and Resources Advisory Panel

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-12

    ... and Resources Advisory Panel (ORRAP) will hold its first regularly scheduled meeting of the year. The meeting will be open to the public. DATES: The meeting will be held on Monday, March 15, 2010, from 8:30 a.m. to 5:30 p.m. and on Tuesday, March 16, 2010, from 8:30 a.m. to 2 p.m. ADDRESSES: The meeting will...

  5. 78 FR 938 - Notification of a Public Meeting and a Public Teleconference of the Clean Air Scientific Advisory...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-07

    .... to 4:00 p.m. (Eastern Time). ADDRESSES: The CASAC Lead Review Panel face-to-face public meeting will... Quality Standards (First External Review Draft--January 2013). DATES: The CASAC Lead Review Panel face-to-face public meeting will be held on Tuesday, February 5, 2013, from 8:30 a.m. to 5:30 p.m. (Eastern...

  6. 78 FR 28244 - Arts Advisory Panel Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-14

    .... Dates: June 12, 2013; 2:00 p.m. to 4:00 p.m. EDT. Music (application review): Room 714. This meeting... closed. Dates: June 14, 2013; 9:00 a.m. to 5:00 p.m. EDT. Music (application review): Room 714. This...

  7. 75 FR 57967 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-23

    ... personal privacy. Name of Committee: Biology of Development and Aging Integrated Review Group; Aging Systems and Geriatrics Study Section. Date: October 4, 2010. Time: 8 a.m. to 6 p.m. Agenda: To review and... Emphasis Panel; RFA Panel: Scientific Models to Improve Health. Date: October 20, 2010. Time: 8 a.m. to 6 p...

  8. 77 FR 58871 - Proposal Review Panel for Materials Research; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-24

    ... Source (CHESS) at Cornell University by the Division of Materials Research (DMR) 1203 Dates & Times... and further support of the CHESS facility at Cornell. Agenda Sunday, October 28, 2012 5:45 p.m.-7 p.m. Closed--Executive Session 7 p.m.-8:30 p.m. Open--Tour of CHESS Monday, October 29, 2012 8 a.m.-4 p.m...

  9. 75 FR 4831 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-29

    ... Emphasis Panel Molecular Biology. Date: March 2, 2010. Time: 12 p.m. to 2 p.m. Agenda: To review and...; Special Topic: Diet and Physical Activity Methodologies. Date: March 3-4, 2010. Time: 8 a.m. to 5 p.m...

  10. 76 FR 20359 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-12

    ... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel; PA10-067: Stem Cells and Diabetic Skin... Major Ongoing Clinical Research Studies in CKD (R01). Date: May 17, 2011. Time: 2 p.m. to 3:30 p.m... . (Catalogue of Federal Domestic Assistance Program Nos. 93.847, Diabetes, Endocrinology and Metabolic Research...

  11. 78 FR 34663 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-10

    ... Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings Pursuant to section 10(d) of the... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel, PAR-12-265 Ancillary Studies: The Microbiome in Child Health, Development and Obesity. Date: June 21, 2013. Time: 1:30 p.m. to 3:00 p.m. Agenda...

  12. 75 FR 77674 - National Endowment for the Arts; Arts Advisory Panel

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-13

    ... meeting, from 9 a.m. to 5:30 p.m., will be open. Music (review of nominations): January 25, 2011, by teleconference. This meeting, from 3 p.m. to 3:55 p.m., will be closed. Music (review of nominations): January 25...

  13. Effects of Airborne Particulate Matter on Respiratory Health in a Community near a Cement Factory in Chilanga, Zambia: Results from a Panel Study

    PubMed Central

    Nkhama, Emmy; Ndhlovu, Micky; Dvonch, J. Timothy; Lynam, Mary; Mentz, Graciela; Siziya, Seter; Voyi, Kuku

    2017-01-01

    We conducted a panel study to investigate seasonal variations in concentrations of airborne PM2.5 and PM10 and the effects on respiratory health in a community near a cement factory; in Chilanga; Zambia. A panel of 63 and 55 participants aged 21 to 59 years from a community located at the edge of the factory within 1 km and a control community located 18 km from the factory respectively; were followed up for three climatic seasons July 2015 to February 2016. Symptom diary questionnaires were completed and lung function measurements taken daily for 14 days in each of the three climatic seasons. Simultaneously, PM2.5 and PM10 concentrations in ambient air were monitored at a fixed site for each community. Mean seasonal concentrations of PM2.5 and PM10 ranged from 2.39–24.93 μg/m3 and 7.03–68.28 μg/m3 respectively in the exposed compared to the control community 1.69–6.03 μg/m3 and 2.26–8.86 μg/m3. The incident rates of reported respiratory symptoms were higher in the exposed compared to the control community: 46.3 vs. 13.8 for cough; 41.2 vs. 9.6 for phlegm; 49.0 vs.12.5 for nose; and 13.9 vs. 3.9 for wheeze per 100 person-days. There was a lower performance on all lung indices in the exposed community compared to the control; overall the mean FEV1 (forced expiratory volume in one second) and FVC (forced vital capacity) predicted percentage for the exposed was six and four percentage points lower than the control. Restriction of industrial emissions coupled with on-going monitoring and regulatory enforcement are needed to ensure that PM (airborne particulate matter) levels in the ambient air are kept within recommended levels to safeguard the respiratory health of nearby community residents. PMID:29113101

  14. Recent versus chronic exposure to particulate matter air pollution in association with neurobehavioral performance in a panel study of primary schoolchildren.

    PubMed

    Saenen, Nelly D; Provost, Eline B; Viaene, Mineke K; Vanpoucke, Charlotte; Lefebvre, Wouter; Vrijens, Karen; Roels, Harry A; Nawrot, Tim S

    2016-10-01

    Children's neuropsychological abilities are in a developmental stage. Recent air pollution exposure and neurobehavioral performance are scarcely studied. In a panel study, we repeatedly administered to each child the following neurobehavioral tests: Stroop Test (selective attention) and Continuous Performance Test (sustained attention), Digit Span Forward and Backward Tests (short-term memory), and Digit-Symbol and Pattern Comparison Tests (visual information processing speed). At school, recent inside classroom particulate matter ≤2.5 or 10μm exposure (PM2.5, PM10) was monitored on each examination day. At the child's residence, recent (same day up to 2days before) and chronic (365days before examination) exposures to PM2.5, PM10 and black carbon (BC) were modeled. Repeated neurobehavioral test performances (n=894) of the children (n=310) reflected slower Stroop Test (p=0.05) and Digit-Symbol Test (p=0.01) performances with increasing recent inside classroom PM2.5 exposure. An interquartile range (IQR) increment in recent residential outdoor PM2.5 exposure was associated with an increase in average latency of 0.087s (SE: ±0.034; p=0.01) in the Pattern Comparison Test. Regarding chronic exposure at residence, an IQR increment of PM2.5 exposure was associated with slower performances in the Continuous Performance (9.45±3.47msec; p=0.007) and Stroop Tests (59.9±26.5msec; p=0.02). Similar results were obtained for PM10 exposure. In essence, we showed differential neurobehavioral changes robustly and adversely associated with recent or chronic ambient exposure to PM air pollution at residence, i.e., with recent exposure for visual information processing speed (Pattern Comparison Test) and with chronic exposure for sustained and selective attention. Copyright © 2016. Published by Elsevier Ltd.

  15. 77 FR 11138 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-24

    ... . Name of Committee: Center for Scientific Review Special Emphasis Panel; PAR10-225: Program Project... Emphasis Panel; RFA Panel: Developmental System Biology. Date: March 22-23, 2012. Time: 8 a.m. to 5:30 p.m... 11139

  16. 78 FR 19535 - Proposal Review Panel for Materials Research; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-01

    ... Source (CHESS) at Cornell University by the Division of Materials Research (DMR) 1203 Dates & Times... and further support of the CHESS facility at Cornell. Agenda: Sunday, April 28, 2013 5:45 p.m.-7:15 p...:00 a.m.-3:00 p.m. Open--Review of CHESS 3:00 p.m.-4:40 p.m. Closed--Executive session 4:40 p.m.-8:00...

  17. 77 FR 10574 - Proposal Review Panel for Chemistry; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-22

    ... 5, 2012 8 a.m.-9:15 a.m. Closed-Executive Session 9:15 a.m.-12:15 p.m. Open-CEOP Center & Poster... a.m.-11:30 p.m. Open-CENECI Center & Poster Presentations 11:30 p.m. -1 p.m. Closed-Executive..., 2012 8 a.m.-8:30 a.m. Closed-Executive Session 8:30 a.m.-11:30 p.m. Open-CSCHF Center & Poster...

  18. Interprofessional population health advocacy: Developing and implementing a panel management curriculum in five Veterans Administration primary care practices.

    PubMed

    Dulay, Maya; Bowen, Judith L; Weppner, William G; Eastburn, Abigail; Poppe, Anne P; Spanos, Pete; Wojtaszek, Danielle; Printz, Destiny; Kaminetzky, Catherine P

    2018-05-10

    Health care systems expect primary care clinicians to manage panels of patients and improve population health, yet few have been trained to do so. An interprofessional panel management (PM) curriculum is one possible strategy to address this training gap and supply future primary care practices with clinicians and teams prepared to work together to improve the health of individual patients and populations. This paper describes a Veterans Administration (VA) sponsored multi-site interprofessional PM curriculum development effort. Five VA Centers of Excellence in Primary Care Education collaborated to identify a common set of interprofessionally relevant desired learning outcomes (DLOs) for the PM and to develop assessment instruments for monitoring trainees' PM learning. Authors cataloged teaching and learning activities across sites. Results from pilot testing were systematically discussed leading to iterative revisions of curricular elements. Authors completed a retrospective self-assessment of curriculum implementation for the academic year 2015-16 using a 5-point scale: contemplation (score = 0), pilot (1), action (2), maintenance (3), and embedded (4). Implementation scores were analyzed using descriptive statistics. DLOs were organized into five categories (individual patients, populations, guidelines/measures, teamwork, and improvement) along with a developmental continuum and mapped to program competencies. Instruction and implementation varied across sites based on resources and priorities. Between 2015 and 2016, 159 trainees (internal medicine residents, nurse practitioner students and residents, pharmacy residents, and psychology post-doctoral fellows) participated in the PM curriculum. Curriculum implementation scores for guidelines/measures and improvement DLOs were similar for all trainees; scores for individual patients, populations, and teamwork DLOs were more advanced for nurse practitioner and physician trainees. In conclusion, collaboratively identified DLOs for PM guided development of assessment instruments and instructional approaches for panel management activities in interprofessional teams. This PM curriculum and associated tools provide resources for educators in other settings.

  19. 77 FR 33475 - National Institute On Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-06

    ...; Stress and Aging. Date: July 9, 2012. Time: 9:00 a.m. to 1:00 p.m. Agenda: To review and evaluate grant... Panel; Health, Sex, and Aging. Date: July 18, 2012. Time: 1:00 p.m. to 5:00 p.m. Agenda: To review and...

  20. 76 FR 30308 - Pacific Fishery Management Council; Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-25

    ... Stock Assessment Review Panel (STAR Panel) for the Pacific ocean perch and petrale sole stock assessments will hold a work session that is open to the public. DATES: The STAR Panel for Pacific ocean perch... 5:30 p.m. or as necessary to complete business for the day. The STAR panel will reconvene on Tuesday...

  1. 76 FR 27375 - Medical Review Board Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-11

    ... Period 11:45A-12:45 p.m. Break for Lunch 12:45-2 p.m. Update on 2007 Evidence Report on Sleep Apnea; Overview of 2007 Medical Expert Panel Opinions on Sleep Apnea 2-2:30 p.m. Review on Previous MRB recommendations on Sleep Apnea 2:30 -4 p.m. Public Comment Period Breaks will be announced on meeting day and may...

  2. 76 FR 66734 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-27

    ... for Scientific Review Special Emphasis Panel, Member Conflict: Brain Diseases--Multiple Sclerosis, Amyotrophic Lateral Sclerosis, Frontal Temporal Dementia. Date: November 17, 2011. Time: 1 p.m. to 3 p.m...

  3. 78 FR 69138 - Proposal Review Panel for Computing Communication Foundations; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-18

    ... NATIONAL SCIENCE FOUNDATION Proposal Review Panel for Computing Communication Foundations; Notice... National Science Foundation announces the following meeting: Name: Site Visit, Proposal Panel Review for Science and Technology Centers--Integrative Partnerships ( 1192). Date/Time: December 3, 2013, 6:30 p.m.-8...

  4. 77 FR 70483 - Proposal Review Panel for Computing Communication Foundations; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-26

    ... NATIONAL SCIENCE FOUNDATION Proposal Review Panel for Computing Communication Foundations; Notice... National Science Foundation announces the following meeting: Name: Site Visit, Proposal Panel Review for Science and Technology Centers--Integrative Partnerships ( 1192). Date/Time: December 3, 2012, 6:30 p.m.-8...

  5. 75 FR 5353 - Proposal Review Panel for Chemistry; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-02

    ... NATIONAL SCIENCE FOUNDATION Proposal Review Panel for Chemistry; Notice of Meeting In accordance... Georgia Institute of Technology and The University of Massachusetts, Proposal Review Panel for Chemistry... a.m.-8 p.m. Places: Department of Chemistry, Georgia Institute of Technology, Atlanta, GA 30332...

  6. Physiological and perceived health effects from daily changes in air pollution and weather among persons with heart failure: a panel study.

    PubMed

    Goldberg, Mark S; Wheeler, Amanda J; Burnett, Richard T; Mayo, Nancy E; Valois, Marie-France; Brophy, James M; Giannetti, Nadia

    2015-01-01

    We carried out this daily diary panel study in Montreal, Quebec, to determine whether oxygen saturation, pulse rate, blood pressure, self-rated health, and shortness of breath at night were associated with concentrations of indoor carbon monoxide (CO), and indoor and outdoor fine particles (PM2.5), temperature, and relative humidity. Over a 2-month consecutive period between 2008 and 2010, we measured daily indoor and outdoor levels of the air pollutants and weather variables and 55 subjects measured their daily health and other variables. To estimate the associations between the health outcomes and the environmental exposures, we used a mixed effects regression model using an autoregressive model of order-one and we adjusted for month and day and personal variables. The general pattern of associations can be summarized as follows: oxygen saturation was reduced for increases in indoor- and outdoor-PM2.5 and temperature. Pulse rate increased on the concurrent day for increases in indoor CO and PM2.5. Diastolic blood pressure increased with increasing indoor and outdoor PM2.5 and relative humidity. Systolic blood pressure increased with indoor PM2.5 and decreased with increasing indoor and outdoor temperature. Self-rated health diminished with increases in outdoor PM2.5 and indoor and outdoor temperature. Self-reported shortness of breath at night increased with increasing indoor and outdoor temperatures. Health in heart failure is affected in the short term by personal and environmental conditions that are manifest in intermediate physiological parameters.

  7. The Impact of Air Pollution, Including Asian Sand Dust, on Respiratory Symptoms and Health-related Quality of Life in Outpatients With Chronic Respiratory Disease in Korea: A Panel Study.

    PubMed

    Nakao, Motoyuki; Ishihara, Yoko; Kim, Cheol-Hong; Hyun, In-Gyu

    2018-05-01

    Air pollution is a growing concern in Korea because of transboundary air pollution from mainland China. A panel study was conducted to clarify the effects of air pollution on respiratory symptoms and health-related quality of life (HR-QoL) in outpatients with and without chronic obstructive pulmonary disease (COPD) in Korea. Patients filled out a questionnaire including self-reported HR-QoL in February and were followed up in May and July. The study was conducted from 2013 to 2015, with different participants each year. Air quality parameters were applied in a generalized estimating equation as independent variables to predict factors affecting HR-QoL. Lower physical fitness scores were associated with Asian sand dust events. Daily activity scores were worse when there were high concentrations of particulate matter (PM) less than 10 μm in diameter (PM 10 ). Lower social functioning scores were associated with high PM less than 2.5 μm in diameter and nitrogen dioxide (NO 2 ) concentrations. High NO 2 concentrations also showed a significant association with mental health scores. Weather-related cough was prevalent when PM 10 , NO 2 , or ozone (O 3 ) concentrations were high, regardless of COPD severity. High PM 10 concentrations were associated with worsened wheezing, particularly in COPD patients. The results suggest that PM, NO 2 , and O 3 cause respiratory symptoms leading to HR-QoL deterioration. While some adverse effects of air pollution appeared to occur regardless of COPD, others occurred more often and more intensely in COPD patients. The public sector, therefore, needs to consider tailoring air pollution countermeasures to people with different conditions to minimize adverse health effects.

  8. Estimation of personal PM2.5 and BC exposure by a modeling approach - Results of a panel study in Shanghai, China.

    PubMed

    Chen, Chen; Cai, Jing; Wang, Cuicui; Shi, Jingjin; Chen, Renjie; Yang, Changyuan; Li, Huichu; Lin, Zhijing; Meng, Xia; Zhao, Ang; Liu, Cong; Niu, Yue; Xia, Yongjie; Peng, Li; Zhao, Zhuohui; Chillrud, Steven; Yan, Beizhan; Kan, Haidong

    2018-06-06

    Epidemiologic studies of PM 2.5 (particulate matter with aerodynamic diameter ≤2.5 μm) and black carbon (BC) typically use ambient measurements as exposure proxies given that individual measurement is infeasible among large populations. Failure to account for variation in exposure will bias epidemiologic study results. The ability of ambient measurement as a proxy of exposure in regions with heavy pollution is untested. We aimed to investigate effects of potential determinants and to estimate PM 2.5 and BC exposure by a modeling approach. We collected 417 24 h personal PM 2.5 and 130 72 h personal BC measurements from a panel of 36 nonsmoking college students in Shanghai, China. Each participant underwent 4 rounds of three consecutive 24-h sampling sessions through December 2014 to July 2015. We applied backwards regression to construct mixed effect models incorporating all accessible variables of ambient pollution, climate and time-location information for exposure prediction. All models were evaluated by marginal R 2 and root mean square error (RMSE) from a leave-one-out-cross-validation (LOOCV) and a 10-fold cross-validation (10-fold CV). Personal PM 2.5 was 47.6% lower than ambient level, with mean (±Standard Deviation, SD) level of 39.9 (±32.1) μg/m 3 ; whereas personal BC (6.1 (±2.8) μg/m 3 ) was about one-fold higher than the corresponding ambient concentrations. Ambient levels were the most significant determinants of PM 2.5 and BC exposure. Meteorological and season indicators were also important predictors. Our final models predicted 75% of the variance in 24 h personal PM 2.5 and 72 h personal BC. LOOCV analysis showed an R 2 (RMSE) of 0.73 (0.40) for PM 2.5 and 0.66 (0.27) for BC. Ten-fold CV analysis showed a R 2 (RMSE) of 0.73 (0.41) for PM 2.5 and 0.68 (0.26) for BC. We used readily accessible data and established intuitive models that can predict PM 2.5 and BC exposure. This modeling approach can be a feasible solution for PM exposure estimation in epidemiological studies. Copyright © 2018 Elsevier Ltd. All rights reserved.

  9. 77 FR 55526 - Open Meeting of the Taxpayer Advocacy Panel Refund Processing Communications Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-10

    ... Refund Processing Communications Project Committee AGENCY: Internal Revenue Service (IRS), Treasury... Communications Project Committee will be conducted. The Taxpayer Advocacy Panel is soliciting public comments... Panel Refund Processing Communications Project Committee will be held Thursday, October 4, 2012 at 2 p.m...

  10. 78 FR 78517 - Open Meeting of the Taxpayer Advocacy Panel Taxpayer Communications Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-26

    ... Taxpayer Communications Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of Meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Taxpayer Communications Project... Panel Taxpayer Communications Project Committee will be held Thursday, January 23, 2014, at 2:00 p.m...

  11. 78 FR 64063 - Open Meeting of the Taxpayer Advocacy Panel Taxpayer Communications Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-25

    ... Taxpayer Communications Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Taxpayer Communications Project... Panel Taxpayer Communications Project Committee will be held Thursday, November 21, 2013, at 2:00 p.m...

  12. 78 FR 3501 - Open Meeting of the Taxpayer Advocacy Panel Taxpayer Communications Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-16

    ... Taxpayer Communications Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Taxpayer Communications Project... Panel Taxpayer Communications Project Committee will be held Thursday, February 21, 2013 at 2:00 p.m...

  13. 78 FR 56270 - Open Meeting of the Taxpayer Advocacy Panel Taxpayer Communications Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-12

    ... Taxpayer Communications Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Taxpayer Communications Project... Panel Taxpayer Communications Project Committee will be held Thursday, October 17, 2013, at 2:00 p.m...

  14. 77 FR 74920 - Open Meeting of the Taxpayer Advocacy Panel Taxpayer Communications Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-18

    ... Taxpayer Communications Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Taxpayer Communications Project... Panel Taxpayer Communications Project Committee will be held Thursday, January 17, 2013 from 2:00 p.m...

  15. 78 FR 41193 - Open Meeting of the Taxpayer Advocacy Panel Taxpayer Communications Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-09

    ... Taxpayer Communications Project Committee AGENCY: Internal Revenue Service (IRS) Treasury. ACTION: Notice of Meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Taxpayer Communications Project... Panel Taxpayer Communications Project Committee will be held Thursday, August 15, 2013, at 2:00 p.m...

  16. 75 FR 3942 - Proposal Review Panel for Chemistry; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-25

    ... NATIONAL SCIENCE FOUNDATION Proposal Review Panel for Chemistry; Notice of Meeting In accordance..., Proposal Review Panel for Chemistry, 1191. Dates & Times: February 23, 2010; 8:30 a.m.-4:30 p.m. February... Brittain, Program Director, Chemistry Centers Program, Division of Materials Research, Room 1055, National...

  17. 78 FR 43003 - Biomedical Laboratory Research and Development Service, Special Emphasis Panel-Amyotrophic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-18

    ... Emphasis Panel--Amyotrophic Lateral Sclerosis (ALS) Brain Bank, Notice of Meeting The Department of... Special Emphasis Panel--ALS Brain Bank will meet on July 23, 2013, from 9 a.m. until 4 p.m. in Building 57... VA ALS Brain Bank for its continued funding. The VA ALS Brain Bank is a project of high programmatic...

  18. EXPOSURE ANALYSIS FROM PERSONAL AND AMBIENT AIR SAMPLING: RESULTS OF THE 1998 BALTIMORE STUDY

    EPA Science Inventory

    An integrated epidemiological-exposure panel study was conducted during July-August 1998 which focused upon establishing relationships between potential human exposures to particulate matter (PM) and related co-pollutants with detectable health effects. The study design incorpo...

  19. 75 FR 56116 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-15

    ... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel, Alzheimer's Disease Genetics. Date: October 4, 2010. Time: 8 p.m. to 9 p.m. Agenda: To review and evaluate grant...

  20. 77 FR 65570 - Center for Scientific Review; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-29

    ... personal privacy. Name of Committee: Center for Scientific Review Special Emphasis Panel; Biomedical Imaging and Engineering AREA Review. Date: October 18, 2012. Time: 2:00 p.m. to 5:00 p.m. Agenda: To...

  1. 76 FR 36931 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-23

    ..., Prevention and Intervention for Addictions. Date: July 20, 2011. Time: 1 p.m. to 1:50 p.m. Agenda: To review... Review Special Emphasis Panel, Member Conflict: Risk, Prevention and Intervention for Addictions. Date...

  2. 78 FR 18357 - Center for Scientific Review; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-26

    ... personal privacy. Name of Committee: Center for Scientific Review Special Emphasis Panel; Fellowships: Cell Biology, Developmental Biology, and Bioengineering. Date: April 3, 2013. Time: 1:00 p.m. to 2:00 p.m...

  3. 75 FR 36662 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-28

    ...; Neurogenesis, Stem Cells, and Transcription Factors. Date: July 29, 2010. Time: 12 p.m. to 2 p.m. Agenda: To...: Translational Research in Pediatric and Obstetric Pharmacology. Date: July 21, 2010. Time: 11 a.m. to 2:30 p.m... for Scientific Review Special Emphasis Panel; Review of the Mass Spectrometry Research Center. Date...

  4. 75 FR 17416 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-06

    ... Special Emphasis Panel, Member Conflict: Cancer Research. Date: April 21, 2010. Time: 3 p.m. to 5 p.m... Biology Research Review. Date: May 5-6, 2010. Time: 9 a.m. to 5 p.m. Agenda: To review and evaluate grant... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review...

  5. 75 FR 32817 - National Endowment for the Arts; Arts Advisory Panel

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-09

    ... meeting, from 9 a.m. to 6 p.m. on July 8th and from 9 a.m. to 3 p.m. on July 9th, will be closed. Music... 22nd, and from 9 a.m. to 3 p.m. on July 23rd, will be closed. Music (application review): July 27-30...

  6. 78 FR 64026 - Arts Advisory Panel Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-25

    ... closed. Dates: November 14, 2013 in Room 714. 9:00 a.m. to 5:00 p.m. Eastern time. Music (application...:00 p.m. Eastern time. Music (application review): This meeting will be closed. Dates: November 19, 2013. 9:00 a.m. to 3:00 p.m. Eastern time in room 714. Music (application review): This meeting will be...

  7. 75 FR 18512 - National Institute on Deafness and Other Communication Disorders; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-12

    ... Deafness and Other Communication Disorders Special Emphasis Panel, LRP's. Date: May 3, 2010. Time: 1 p.m..., 6120 Executive Blvd., Rockville, MD 20852. (Virtual Meeting.) Contact Person: Sheo Singh, PhD...'s Clinical Trial. Date: May 7, 2010. Time: 4 p.m. to 5 p.m. Agenda: To review and evaluate grant...

  8. 78 FR 36201 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-17

    ... Emphasis Panel; PAR-11-100: Alzheimer's Disease Pilot Clinical Trials. Date: July 17, 2013. Time: 2:00 p.m... for Scientific Review Special Emphasis Panel; Microbiology and Infectious Diseases AREA Review. Date...

  9. 76 FR 5597 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-01

    ... Special Emphasis Panel; Drug Discovery for the Nervous System. Date: February 25, 2011. Time: 1 p.m. to 4... Scientific Review Special Emphasis Panel; Small Business: Biomaterials, Delivery Systems, and Nanotechnology...

  10. 77 FR 31861 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-30

    ... Special Emphasis Panel; Member Conflict: Teen Relationship Violence. Date: June 20, 2012. Time: 2:00 p.m... personal privacy. Name of Committee: Center for Scientific Review Special Emphasis Panel; Member Conflict...

  11. Association between pulmonary function and daily levels of sand dust particles assessed by light detection and ranging in schoolchildren in western Japan: A panel study.

    PubMed

    Watanabe, Masanari; Noma, Hisashi; Kurai, Jun; Kato, Kazuhiro; Sano, Hiroyuki; Tatsukawa, Toshiyuki; Nakazaki, Hirofumi; Yamasaki, Akira; Shimizu, Eiji

    2016-01-01

    An important aspect of sand dust emissions in association with respiratory disorders is the quantity of particulate matter. This is usually expressed as particulate matter less than 10 μm (PM10) and 2.5 μm (PM2.5). However, the composition of PM10 and PM2.5 varies. Light detection and ranging is used to monitor sand dust particles originating in East Asian deserts and distinguish them from air pollution aerosols. The objective of this study was to investigate the association between the daily levels of sand dust particles and pulmonary function in schoolchildren in western Japan. In this panel study, the peak expiratory flow (PEF) of 399 schoolchildren was measured daily from April to May 2012. A linear mixed model was used to estimate the association of PEF with the daily levels of sand dust particles, suspended particulate matter (SPM), and PM2.5. There was no association between the daily level of sand dust particles and air pollution aerosols, while both sand dust particles and air pollution aerosols had a significant association with SPM and PM2.5. An increment of 0.018 km(-1) in sand dust particles was significantly associated with a decrease in PEF (-3.62 L/min; 95% confidence interval, -4.66 to -2.59). An increase of 14.0 μg/m(3) in SPM and 10.7 μg/m(3) in PM2.5 led to a significant decrease of -2.16 L/min (-2.88 to -1.43) and -2.58 L/min (-3.59 to -1.57), respectively, in PEF. These results suggest that exposure to sand dust emission may relate to pulmonary dysfunction in children in East Asia. Copyright © 2015 The Authors. Production and hosting by Elsevier B.V. All rights reserved.

  12. 76 FR 45004 - Open Meeting of the Taxpayer Advocacy Panel Volunteer Income Tax Assistance Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-27

    ... Volunteer Income Tax Assistance Project Committee AGENCY: Internal Revenue Service (IRS) Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Volunteer Income Tax... Panel Volunteer Income Tax Assistance Project Committee will be held Tuesday, September 13, 2011, 2 p.m...

  13. 76 FR 63716 - Open Meeting of the Taxpayer Advocacy Panel Volunteer Income Tax Assistance Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-13

    ... Volunteer Income Tax Assistance Project Committee AGENCY: Internal Revenue Service (IRS) Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Volunteer Income Tax... Panel Volunteer Income Tax Assistance Project Committee will be held Tuesday, November 08, 2011, 2 p.m...

  14. 75 FR 56158 - Industry Advisory Panel: Notice of Open Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-15

    ... DEPARTMENT OF STATE [Public Notice 7107] Industry Advisory Panel: Notice of Open Meeting The Industry Advisory Panel of the Bureau of Overseas Buildings Operations will meet on Thursday, October 14, 2010 from 9:30 a.m. until 3:30 p.m. Eastern Daylight Time. The meeting is open to the public and will...

  15. 76 FR 62892 - Industry Advisory Panel: Notice of Open Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-11

    ... DEPARTMENT OF STATE [Public Notice: 7598] Industry Advisory Panel: Notice of Open Meeting The Industry Advisory Panel of the Bureau of Overseas Buildings Operations will meet on Tuesday, October 18, 2011 from 9:30 a.m. until 3:30 p.m. Eastern Daylight Time. The meeting is open to the public and will...

  16. 75 FR 13643 - Industry Advisory Panel: Notice of Open Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-22

    ... DEPARTMENT OF STATE [Public Notice 6909] Industry Advisory Panel: Notice of Open Meeting The Industry Advisory Panel of the Bureau of Overseas Buildings Operations will meet on Wednesday, April 14, 2010 from 9:30 a.m. until 3:30 p.m. Eastern Daylight Time. The meeting is open to the public, as...

  17. 76 FR 45006 - Open Meeting of the Taxpayer Advocacy Panel Earned Income Tax Credit Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-27

    ... Earned Income Tax Credit Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Earned Income Tax Credit... Panel Earned Income Tax Credit Project Committee will be held Monday, September 26, 2011, at 3 p.m...

  18. 75 FR 57042 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-17

    ...: Center for Scientific Review Special Emphasis Panel; PAR-08-062: Alzheimer's Disease Pilot Clinical... Diseases. Date: October 25, 2010. Time: 4:30 p.m. to 5:30 p.m. Agenda: To review and evaluate grant...

  19. 77 FR 55847 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-11

    ... Scientific Review Special Emphasis Panel; PAR09-259: Optimization of Small Molecule Probes For the Nervous System. Date: October 12, 2012. Time: 3 p.m. to 4 p.m. Agenda: To review and evaluate grant applications...

  20. 78 FR 57400 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-18

    ....gov . Name of Committee: Center for Scientific Review Special Emphasis Panel; Biomedical Imaging and Engineering Area Review. Date: October 11, 2013. Time: 1:00 p.m. to 6:00 p.m. Agenda: To review and evaluate...

  1. 77 FR 65005 - Center for Scientific Review Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-24

    ... personal privacy. Name of Committee: Center for Scientific Review Special Emphasis Panel; Biomedical Imaging and Engineering AREA Review. Date: October 18, 2012 Time: 2:00 p.m. to 5:00 p.m. Agenda: To review...

  2. 77 FR 16845 - Center for Scientific Review; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-22

    ... personal privacy. Name of Committee: Center for Scientific Review Special Emphasis Panel; Center: Mass Spectrometry Resource for Biology and Medicine. Date: April 1-3, 2012. Time: 8 p.m. to 12 p.m. Agenda: To...

  3. 78 FR 36553 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-18

    ... . Name of Committee: Center for Scientific Review Special Emphasis Panel Member Conflict: Cell Biology... Structure, Function and Regeneration Date: July 18, 2013. Time: 1:00 p.m. to 4:00 p.m. Agenda: To review and...

  4. 76 FR 72958 - Center For Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-28

    ... Special Emphasis Panel; Tissue Engineering and Signaling. Date: December 13, 2011. Time: 3 p.m. to 4 p.m... Domestic Assistance Program Nos. 93.306, Comparative Medicine; 93.333, Clinical Research, 93.306, 93.333...

  5. 78 FR 67177 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-08

    ... personal privacy. Name of Committee: Center for Scientific Review Special Emphasis Panel; Molecular Genetics B (MGB). Date: November 25, 2013. Time: 3:00 p.m. to 4:30 p.m. Agenda: To review and evaluate...

  6. 77 FR 40368 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-09

    ... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel Age, Gene..., Genes and Longevity in Humans. Date: July 27, 2012. Time: 12:30 p.m. to 4 p.m. Agenda: To review and...

  7. 76 FR 10912 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-28

    ... personal privacy. Name of Committee: Center for Scientific Review Special Emphasis Panel; Member Conflict...; Genetic Disease and Development. Date: March 14, 2011. Time: 12 p.m. to 2:20 p.m. Agenda: To review and...

  8. 78 FR 26793 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-08

    ... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Asthma in Older Adults. Date: May 29, 2013. Time: 12:00 p.m. to 3:00 p.m. Agenda: To review and evaluate grant...

  9. 77 FR 65698 - Center for Scientific Review; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-30

    ... personal privacy. Name of Committee: Center for Scientific Review Special Emphasis Panel, Dating Violence and Marketing. Date: November 13, 2012. Time: 1:00 p.m. to 2:00 p.m. Agenda: To review and evaluate...

  10. 76 FR 22112 - National Human Genome Research Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-20

    ... Emphasis Panel, Special Emphasis Panel (SEP)--Model Organism database (MOD). Date: June 20, 2011. Time: 8 a.m. to 5 p.m. Agenda: To review and evaluate grant applications. Place: Crystal Gateway Marriott...

  11. 75 FR 46950 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-04

    ... Panel, Member Conflict: Cardiovascular Disease Epidemiology. Date: September 8, 2010. Time: 12 p.m. to 2... Review Group, Genetics of Health and Disease Study Section. Date: September 30-October 1, 2010. Time: 8...

  12. 78 FR 28231 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-14

    ... Behavior Integrated Review Group, Social Psychology, Personality and Interpersonal Processes Study Section... Emphasis Panel, Stress and Social Support Across the Lifespan. Date: June 10, 2013. Time: 1:00 p.m. to 2:00...

  13. 75 FR 41505 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-16

    ... for Scientific Review Special Emphasis Panel; Mass Spectrometry Shared Instrumentation Study Section... Instrumentation: Mass Spectrometers. Date: August 5-6, 2010. Time: 8:30 a.m. to 5 p.m. Agenda: To review and...

  14. 75 FR 32954 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-10

    ... Aging Special Emphasis Panel; Antecedent Markers for Alzheimer's Disease. Date: July 26, 2010. Time: 2 p..., Disease, and Death. Date: June 23-24, 2010. Time: 3 p.m. to 12 p.m. Agenda: To review and evaluate grant...

  15. Differential pulmonary and cardiac effects of pulmonary exposure to a panel of PM-associated metals

    EPA Science Inventory

    Biological mechanisms underlying the epidemiological association between exposure to particulate matter (PM) and increased risk of cardiovascular health effects are under investigation. Water soluble metals reaching systemic circulation following pulmonary exposure are likely exe...

  16. 77 FR 33472 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-06

    ... Scientific Review Special Emphasis Panel, PAR09-260: Optimization of Small Molecule Probes for the Nervous System. Date: June 29, 2012. Time: 3:00 p.m. to 5:00 p.m. Agenda: To review and evaluate grant...

  17. 76 FR 68200 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-03

    ...: National Heart, Lung, and Blood Institute Special Emphasis Panel; NHLBI Career Enhancement Grants for Stem Cell Research. Date: November 29, 2011. Time: 1 p.m. to 3 p.m. Agenda: To review and evaluate grant...

  18. 76 FR 31966 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-02

    ...: Neurodegenerative Cardiovascular Disease and Imaging. Date: June 16, 2011. Time: 2 p.m. to 4 p.m. Agenda: To review... Special Emphasis Panel, Small Business: Cardiovascular Sciences. Date: July 7-8, 2011. Time: 7:30 a.m. to...

  19. 76 FR 77841 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-14

    ... Panel, Stem cell applications for Neurodegeneration. Date: January 5, 2012. Time: 3 p.m. to 4 p.m... Nos. 93.306, Comparative Medicine; 93.333, Clinical Research, 93.306, 93.333, 93.337, 93.393-93.396...

  20. 78 FR 45933 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-30

    ... Emphasis Panel Cardiovascular Research Resource. Date: August 22, 2013. Time: 2:30 p.m. to 5:00 p.m. Agenda..., Heart and Vascular Diseases Research; 93.838, Lung Diseases Research; 93.839, Blood Diseases and...

  1. 78 FR 25460 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-01

    ...: Cardiovascular Epidemiology and Infectious Disease. Date: May 28, 2013. Time: 1:00 p.m. to 3:00 p.m. Agenda: To... for Scientific Review Special Emphasis Panel Member Conflict: Eye Diseases 4. Date: May 28, 2013. Time...

  2. 77 FR 12856 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-02

    ... Emphasis Panel, NHLBI Cardiovascular T32 Training Application. Date: March 23, 2012. Time: 1 p.m. to 3 p.m..., Heart and Vascular Diseases Research; 93.838, Lung Diseases Research; 93.839, Blood Diseases and...

  3. 76 FR 38404 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-30

    ...: Vascular Biology. Date: July 11, 2011. Time: 12 p.m. to 2 p.m. Agenda: To review and evaluate grant... Scientific Review Special Emphasis Panel, PAR-10-266 Dynamics and Functions of NEDD8 In Cellular Control...

  4. 76 FR 64359 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-18

    ... Brain, Neurotransmission and Aging Special Emphasis Panel. Date: November 1, 2011. Time: 8 a.m. to 5 p.m...: Cell, Computational and Molecular Biology. Date: November 9, 2011. Time: 10 a.m. to 6 p.m. Agenda: To...

  5. 78 FR 38410 - Arts Advisory Panel Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-26

    ... (application review): Room 730. This meeting will be closed. Dates: July 15, 2013; 9:00 a.m. to 5:30 p.m. Music...:30 p.m. Music (application review): Room 714. This meeting will be closed. Dates: July 16, 2013; 10...

  6. 76 FR 5389 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-31

    ... Panel; Member Conflict: Transplantation and Tumor Immunology. Date: February 24, 2011. Time: 1:30 p.m...; Topics in Pathogenic Bacteria. Date: March 2-3, 2011. Time: 9 a.m. to 5 p.m. Agenda: To review and...

  7. [The short-term effects of particulate matter on lung function of college students in autumn and winter in Wuhan].

    PubMed

    Li, Jiao-yuan; Ma, Lu; Liu, Li-zhi; Zhou, Jie; He, Ming-quan; Shima, Masayuki; Tamura, Kenji

    2013-02-01

    To evaluate the effects of indoor and outdoor PM2.5 (fine particulate matter, particulate matter with an aerodynamic diameter ≤ 2.5 µm) on lung function of college students in autumn and winter in Wuhan. In this panel study, 37 college students (excluded subject of respiratory disease and smoking history) aged 19 - 21 were investigated by cluster sampling in a university in Wuhan. The follow-up study lasted for 28 days in total, including two study periods, Oct. 29 to Nov. 11, 2009 (autumn) and Dec. 23, 2009 to Jan.5, 2010 (winter), the peak expiratory flow (PEF) of the college students were measured daily in the morning and evening in the university. PM10 and PM2.5 were monitored indoors and outdoors. The effects of PM on lung function of college students were analyzed by using generalized estimating equation (GEE). Average daily concentrations of indoor, outdoor PM2.5 in autumn were (91.3 ± 43.7) and (104.2 ± 49.4) µg/m(3) respectively, while in winter the concentrations of indoor and outdoor PM2.5 were (110.6 ± 42.3) and (143.5 ± 51.2) µg/m(3). The single pollutant model showed that in winter, the evening PEF decrement was significantly associated with increasing outdoor PM2.5. With an increase of 10 µg/m(3) outdoor PM2.5, the PEF measured in the evening decreased 1.27 L/min (95%CI: 0.02 - 2.52 L/min, respectively). Meanwhile, the results showed that 2-days lagged outdoor PM2.5 was also significantly associated with morning PEF. An increase of 10 µg/m(3) 2-days lagged outdoor PM2.5 caused the decrease of 1.82 L/min (95%CI: -3.53 - -0.11 L/min) of PEF measured in the morning. Controlling the influence of gaseous pollutants and building the two pollutants models, the results indicated that no significant changes of PEF of students being exposed to PM2.5 on same day (lag 0) were observed. However, under consideration of SO2 effect, significant association between an increase of 10 µg/m(3) 2-days lagged outdoor PM2.5 and changes of morning PEF (-1.81 L/min, 95%CI: -3.51 - -0.11 L/min, P = 0.037) was found. The relationship between changes of concentrations and PEF was not observed in autumn in this study. In our panel study, exposure to outdoor PM2.5 is significantly associated with PEF among college students in winter, but not in autumn.

  8. 77 FR 8328 - Open Meeting of the Taxpayer Advocacy Panel Face-to-Face Service Methods Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-14

    ... Face-to-Face Service Methods Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Face-to-Face Service Methods... Panel Face-to-Face Service Methods Project Committee will be held Tuesday, March 13, 2012, at 2 p.m...

  9. 75 FR 33894 - Open Meeting of the Taxpayer Advocacy Panel Tax Forms and Publications/MLI Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-15

    ... Tax Forms and Publications/MLI Project Committee AGENCY: Internal Revenue Service (IRS), Treasury... Publications/MLI Project Committee will be conducted. The Taxpayer Advocacy Panel is soliciting public comments... Panel Tax Forms and Publications/MLI Project Committee will be held Thursday, July 8, 2010, at 1 p.m...

  10. 75 FR 10865 - Open Meeting of the Taxpayer Advocacy Panel Tax Forms and Publications/MLI Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-09

    ... Tax Forms and Publications/MLI Project Committee AGENCY: Internal Revenue Service (IRS), Treasury... Publications/MLI Project Committee will be conducted. The Taxpayer Advocacy Panel is soliciting public comments... Panel Tax Forms and Publications/MLI Project Committee will be held Thursday, April 8, 2010, at 1 p.m...

  11. 76 FR 19826 - Industry Advisory Panel; Notice of Open Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-08

    ... DEPARTMENT OF STATE [Public Notice: 7330] Industry Advisory Panel; Notice of Open Meeting The Industry Advisory Panel of the Bureau of Overseas Buildings Operations will meet on Tuesday, April 26, 2011 from 9:30 a.m. until 3:30 p.m. Eastern Daylight Time. The meeting is open to the public and will be...

  12. 76 FR 6188 - Open Meeting of the Taxpayer Advocacy Panel Earned Income Tax Credit Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-03

    ... Earned Income Tax Credit Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of meeting. SUMMARY: An open Meeting of the Taxpayer Advocacy Panel Earned Income Tax Credit... Panel Earned Income Tax Credit Project Committee will be held Monday, March 28, 2011, at 2 p.m., Eastern...

  13. THE 1998 BALTIMORE PARTICULATE MATTER EPIDEMIOLOGY-EXPOSURE STUDY: PART 2-PERSONAL EXPOSURE ASSESSMENT ASSOCIATED WITH AN ELDERLY STUDY POPULATION

    EPA Science Inventory

    An integrated epidemiological-exposure panel study was conducted during the summer of 1998 which focused upon establishing relationships between potential human exposures to particulate matter (PM) and related co-pollutants with detectable health effects. The study design incor...

  14. 76 FR 12362 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-07

    ... Review Special Emphasis Panel; Chronic Pain Syndromes. Date: March 22-23, 2011. Time: 7 a.m. to 8 p.m.... Name of Committee: Center for Scientific Review Special Emphasis Panel; PAR-08-160: Metabolic Effects...

  15. Modeling Air Pollution Exposure Metrics for the Diabetes and Environment Panel Study (DEPS)

    EPA Science Inventory

    Air pollution health studies of fine particulate matter (PM) often use outdoor concentrations as exposure surrogates. To improve exposure assessments, we developed and evaluated an exposure model for individuals (EMI), which predicts five tiers of individual-level exposure metric...

  16. Ambient and Controlled Particle Exposures as Triggers for Acute ECG Changes.

    PubMed

    Rich, David Q; Peters, Annette; Schneider, Alexandra; Zareba, Wojciech; Breitner, Susanne; Oakes, David; Wiltshire, Jelani; Kane, Cathleen; Frampton, Mark W; Hampel, Regina; Hopke, Philip K; Cyrys, Josef; Utell, Mark J

    2016-05-01

    Previous studies have examined changes in heart rate variability (HRV*) and repolarization associated with increased particulate matter (PM) concentrations on the same and previous few days. However, few studies have examined whether these health responses to PM occur within a few hours or even less. Moreover, it is not clear whether exposure of subjects to ambient or-controlled PM concentrations both lead to similar health effects or whether any of the subjects' individual characteristics modify any of their responses to PM. The aims of the cur- rent study were to investigate whether exposure to PM was associated with rapid changes (< 60 minutes or con- current hour up to a delay of 6 hours) in markers of car- diac rhythni or changes in total antioxidant capacity (a marker of protection against oxidative stress) and whether any PM effects on cardiac rhythm markers were modified by total antioxidant capacity, age, obesity, smoking, hypertension, exertion, prior myocardial infarction (MI), or medication. We obtained data from a completed study in Augsburg, Germany (a panel study in N= 109 subjects, including a group with type 2 diabetes or impaired glucose tolerance [IGT; also known as prediabetes]) and a group of other- wise healthy subjects with a potential genetic susceptibil- ity to detoxifying and inflammatory pathways (Hampel et al. 2012b), as well as three completed studies in Rochester, New York (the REHAB panel study of N= 76 postinfarction patients in a cardiac rehabilitation pro- gram [Rich et al. 2012b]; the UPDIABETES study of con- trolled exposure to ultrafine particles [UFPs, particles with an aerodynamic diameter < 100 nm] of N = 19 patients with type 2 diabetes [Stewart et al. 2010; Vora et al. 2014j; and the UPCON controlled-exposure study of concentrated UFP exposure in N = 20 young, healthy, life- time nonsmokers). Data included 5-minute and 1-hour values for HRV and repolarization parameters from elec- trocardiogram (ECG) recordings and total antioxidant capacity measured in stored blood samples. Ambient con- centrations of UFPs, accumulation-mode particles (AMP, particles with an aerodynamic diameter of 100-500 nm), fine PM (PM2.5, particles with an aerodynamic diameter 2.5 pm), and black carbon (BC) were also available. We first conducted factor analyses in each study to find subgroups of correlated ECG outcomes and to reduce the number of outcomes examined in our statistical models. We then restricted the statistical analyses to the factors and representative.outcomes that were common to all four studies, including total HRV (measured as the standard deviation of normal-to-normal [NN] beat intervals [SDNNj), parasympathetic modulation (measured as the root mean square of the successive differences [RMSSD between adjacent NN beat intervals), and T-wave morphol- ogy (measured as T-wave complexity). Next, we used addi- tive mixed models to estimate the change in each outcome associated with increased pollutant concentrations in the . concurrent and previous 6 hours and with 5-minute inter- vals up to the previous 60 minutes, accounting for the correlation of repeated outcome measures for each subject and adjusting for time trend, hour of the day, temperature, relative humidity, day of the week, month, and visit number. Because multiple comparisons were an issue in our. analyses, we used a discovery-and-replication approach to draw conclusions across studies for each research question. In the Augsburg study, interquartile range (IQR) increases in UFP concentrations lagged 2 to 5 hours were associated with 1%-3% decreases in SDNN (e.g., lagged 3 hours in the group with a genetic susceptibility: -2.26%; 95% confidence interval [CI], -3.98% to -0.53%). In the REHAB study, similarly, IQR increases in UFP concentra- tions in the previous 5 hours were associated with < 3% decreases in SDNN (e.g., lagged 1 hour: -2.69%; 95% CI, -5.13% to -0.26%). We also found decreases in SDNN associated with IQR increases in total particle count-(a surrogate for UFP) in the UPDIABETES study (lagged 1 hour: -13.22%; 95% CI, -24.11% to -2.33%) but not in the UPCON study. In the Augsburg study, IQR increases in PM2.5 concen- trations in the concurrent hour and lagged 1-5 hours, AMP concentrations lagged 1 and 3 hours, and BC con- centrations lagged 1-5 hours were associated with -1%-5% decreases in SDNN (e.g., PM2.5 lagged 2 hours in the group with diabetes or IGT: -4.59%; 95% CI, -7.44% to -1.75%). In the REHAB study, IQR increases in PM2.5 concentrations lagged 5 and 6 hours and AMP concentra- tions in the concurrent hour and lagged up to 5 hours were associated with 1%-2% decreases in SDNN (e.g., PM2.5 lagged 4 hours: -2.13%; 95% CI, -3.91% to -0.35%). In the Augsburg study, IQR increases in PM2.5 concen- trations in the concurrent hour and BC lagged 1 and 6 hours were associated with 3%-7% decreases in RMSSD (e.g., PM2.5 concurrent hour in the group with diabetes or IGT: -7.20%; 95% CI, -12.11% to -2.02%). In the REHAB study, similarly, increases in PM2.5 concen- trations lagged 4 to 6 hours-though not AMP or BC con- centrations at any lag hour-were associated with -2.5%-3.5% decreases in RMSSD (e.g., PM2.5 lagged 5 hours: -3.49%; 95% CI, -6.13% to -0.84%). We did not find consistent evidence of any pollutant effects on T-wave complexity in 1-hour recordings. For 5-minute record- ings, there was no consistent evidence of UFP effects on SDNN, RMSSD, or T-wave complexity at any 5-minute interval within 60 minutes. We further concluded that these replicated hourly effects of UFP and PM2.5 on short-term measures of SDNN and RMSSD generally did not differ between the groups in the studies (i.e., type 2 diabetes, pre-diabetes/IGT, post- infarction, and healthy subjects). Last, we found no con- sistent evidence of effects of any pollutant on total anti- oxidant capacity and no consistent evidence of modification of our PM2.5-outcome associations by any of the potential effect modifiers. Increased UFP concentrations were associated with decreased SDNN in both of the panel studies and one of the two controlled-exposure studies. We also found that decreased SDNN was associated with both increased PM2.5 and AMP concentrations in the previous 6 hours in the panel studies and that decreased RMSSD was associ- ated with increased PM2.5 concentrations in the previous 6 hours in the panel studies. We therefore concluded that the research questions were replicated. Our findings suggest that both UFPs and PM2.5 are associated with autonomic dysfunction within hours of exposure, which may in part. explain the previously reported risk of acute cardiovascular events associated with increased PM in the previous few hours. Despite the heterogeneity of the study populations,and protocols, our findings provided consistent evidence for the induction of rapid pathophysiological responses by UFPs and PM2.5- The absence of consistent associations between UFPs, PM2.5, and these outcomes when examining shorter time intervals indicates that the 5- to 60-minute responses may be less pronounced than the responses occurring within hours. However, the findings from the 5-minute intervals may have been affected by the variety of proto- cols and conditions from study to study as well as by the potential effects of underlying diseases (e.g., healthy indi- viduals versus individuals with diabetes or a recent cor- onary artery. event), physical activity, circadian rhythms, stress, and/or medications.

  17. 76 FR 34086 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-10

    ... Special Emphasis Panel, Nephrotic Syndrome Ancillary Studies. Date: July 13, 2011. Time: 2 to 2:45 p.m... of Federal Domestic Assistance Program Nos. 93.847, Diabetes, Endocrinology and Metabolic Research...

  18. 78 FR 11659 - Center For Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-19

    ..., Computational, and Molecular Biology. Date: March 12, 2013. Time: 8:00 a.m. to 6:00 p.m. Agenda: To review and... Scientific Review Special Emphasis Panel; Member Conflict: Genetics, Informatics and Vision Studies. Date...

  19. 78 FR 57168 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-17

    ....nih.gov . Name of Committee: Center for Scientific Review Special Emphasis Panel; Special: Systemic... Development and Disease Study Section. Date: October 16-17, 2013. Time: 8:00 a.m. to 5:30 p.m. Agenda: To...

  20. 76 FR 72425 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-23

    ... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel; Hemodialysis and Markers of Heart Failure. Date: December 5, 2011. Time: 2 p.m. to 3 p.m. Agenda: To review and evaluate grant applications...

  1. 75 FR 34457 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-17

    ... Institute of Child Health and Human Development Special Emphasis Panel; Data Archive on Adolescent Pregnancy and Pregnancy Prevention. Date: July 7, 2010. Time: 2 p.m. to 4 p.m. Agenda: To review and evaluate...

  2. 76 FR 30733 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-26

    ... Institute of Child Health and Human Development Special Emphasis Panel, Pathophysiology of Intellectual and Developmental Disabilities. Date: June 17, 2011. Time: 2 p.m. to 5 p.m. Agenda: To review and evaluate grant...

  3. 76 FR 34717 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-14

    ... Digestive and Kidney Diseases Special Emphasis Panel, Teen-LABS. Date: July 15, 2011. Time: 2 p.m. to 2 p.m... Nos. 93.847, Diabetes, Endocrinology and Metabolic Research; 93.848, Digestive Diseases and Nutrition...

  4. 77 FR 59938 - Center for Scientific Review Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-01

    ... Panel; Program Project: Drug Addiction. Date: October 30-31, 2012. Time: 8:00 a.m. to 8:30 p.m. Agenda... Biomedical Computational Science and Technology Initiative. Date: October 30, 2012. Time: 3:00 p.m. to 4:00 p...

  5. 78 FR 63483 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-24

    ... 7, 2013. Time: 8:00 a.m. to 2:00 p.m. Agenda: To review and evaluate grant applications. Place: The... Development Data Coordinating Center. Date: November 7, 2013. Time: 2:30 p.m. to 4:00 p.m. Agenda: To review... Institute Special Emphasis Panel; SBIR Phase IIB Bridge Awards. Date: November 8, 2013. Time: 8:00 a.m. to...

  6. 77 FR 67836 - Arts Advisory Panel Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-14

    ...: November 27, 2012; 9:00 a.m. to 6:00 p.m. EST. Music (application review): Virtual, from Room 716. This..., 2012, from 9:00 a.m. to 6:00 p.m. EST. Music (application review): In room 714. This meeting will be... room 716. This meeting will be closed. Dates: November 29, 2012; 9:00 a.m. to 6:30 p.m. EST. Music...

  7. 76 FR 13421 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-11

    ... . Name of Committee: Center for Scientific Review Special Emphasis Panel, PAR-10-279: Robotics Technology...-Agency Robotics SBIR, Panel 1. Date: April 14-15, 2011. Time: 8 a.m. to 5 p.m. Agenda: To review and...

  8. 76 FR 12980 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-09

    ... Emphasis Panel; Program Project: Cell Biology. Date: March 29-30, 2011. Time: 8 a.m. to 5 p.m. Agenda: To... Review Special Emphasis Panel; Program Project: NeuroAIDS Applications. Date: March 30-31, 2011. Time: 8...

  9. 76 FR 30370 - National Institute of Diabetes and Digestive and Kidney Diseases; Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-25

    ... Institute of Diabetes and Digestive and Kidney Diseases Special Emphasis Panel; Obesity and Pregnancy... Special Emphasis Panel; Obesity and Pregnancy. Date: July 14-15, 2011. Time: 8 a.m. to 5 p.m. Agenda: To...

  10. 75 FR 63491 - National Institute on Drug Abuse; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-15

    ... Drug Abuse Special Emphasis Panel, NIDA Research Education and Science Education Program Review (R25... Panel, NIDA Basic Science Conference Grant (R13) Review. Date: October 27, 2010. Time: 9 a.m. to 5 p.m...

  11. Telecommunications equipment power supply in the Arctic by means of solar panels

    NASA Astrophysics Data System (ADS)

    Terekhin, Vladimir; Lagunov, Alexey

    2016-09-01

    Development of the Arctic region is one of the priorities in the Russian Federation. Amongst other things, a reliable telecommunications infrastructure in the Arctic is required. Petrol and diesel generators are traditionally employed but their use has considerable environmental impact. Solar panels can be used as an alternative power source. The electricity generated will be sufficient to supply small-sized telecommunications equipment with total the power of over 80 watts. An installation consisting of the solar modules, a charge controller, batteries, an inverter and load was designed. Tests were conducted at Cape Desire of the Novaya Zemlya (island). The solar panels provided in excess of 80 W from 7 a.m. to 11 p.m. The batteries charge during this time was sufficient to provide the power supply for the communication equipment during the night, from 11 p.m. to 7 a.m. The maximum value of 638 W of the power generation was observed at 3 p.m. The minimum value of 46 W was at 4 a.m. The solar modules thus can be used during the polar day to power the telecommunications equipment.

  12. 77 FR 43344 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-24

    ... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel; RFA-DK-12-006, Promoting Organ and Tissue Donation Among Diverse Populations. Date: August 22, 2012. Time: 1:00 p.m. to 5:00 p.m. Agenda: To...

  13. 77 FR 28392 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-14

    ....'' Contact Person for More Information: Jane Suen, Dr.P.H., M.S., Scientific Review Officer, CDC, 4770 Buford... Disease Control and Prevention (CDC) announces the aforementioned meeting: Time and Date: 12 p.m.-2:30 p.m...

  14. 75 FR 27561 - Disease, Disability, and Injury Prevention and Control; Special Emphasis Panel (SEP): A...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-17

    ... subject to change as priorities dictate. Contact Person For More Information: Jane Suen, Dr.P.H., M.S... Date: 1 p.m.-4 p.m., July 8, 2010 (Closed). Place: Teleconference. Status: The meeting will be closed...

  15. 76 FR 71515 - South Atlantic Fishery Management Council Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-18

    ... Lobster Committee; Law Enforcement Committee; Ecosystem-Based Management Committee; Advisory Panel... . SUPPLEMENTARY INFORMATION: Meeting Dates 1. Spiny Lobster Committee Meeting: December 5, 2011, 1:30 p.m. until 3 p.m. The Spiny Lobster Committee will: Receive a presentation on the process for preparing...

  16. 77 FR 6812 - Center For Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-09

    ...: Tools for Zebrafish Research. Date: March 6-7, 2012. Time: 9 a.m. to 6 p.m. Agenda: To review and... Panel; Neurobiology of Brain Disease and Aging. Date: March 6-7, 2012. Time: 10 a.m. to 5 p.m. Agenda...

  17. IMPLICATIONS OF PARTICULATE MATTER RESEARCH PROGRAM UPON EXPOSURE ASSESSMENT AND APPORTIONMENT AND ATTRIBUTION OF ENVIRONMENTAL EFFECTS

    EPA Science Inventory

    Recent personal exposure panel studies and monitoring programs addressing fine particulate matter (PM) and associated co-pollutants have elucidated the physical and statistical relationships between personal exposures, residential indoor concentrations (and sources), concentratio...

  18. 78 FR 15745 - Proposal Review Panel for Social and Economic Sciences; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-12

    ... NATIONAL SCIENCE FOUNDATION Proposal Review Panel for Social and Economic Sciences; Notice of... Science Foundation (NSF) announces the following Site Visit. Name: Proposal Review Panel for Social and Economic Sciences, 10748. Date and Time: March 21, 2013 8:30 a.m. to 5:00 p.m., March 22, 2013 8:00 a.m. to...

  19. 76 FR 68200 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-03

    ... Panel; Member Conflict: AIDS/HIV Molecular Biology. Date: December 8, 2011. Time: 12 p.m. to 3:30 p.m... Medicine; 93.333, Clinical Research, 93.306, 93.333, 93.337, 93.393-93.396, 93.837-93.844, 93.846-93.878...

  20. 77 FR 52042 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-28

    ... Racial and Ethnic Minority-PA10-236. Date: October 9, 2012. Time: 2 p.m. to 3 p.m. Agenda: To review and... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel; DDK-C Conflicts. Date: October 18, 2012...

  1. 75 FR 79010 - National Cancer Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-17

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute... Cancer Institute Special Emphasis Panel Education. Date: January 25, 2011. Time: 3 p.m. to 4:30 p.m..., Resources and Training Review Branch, Division of Extramural Activities, National Cancer Institute, 6116...

  2. Association of Short-Term Exposure to Ambient Fine Particulate Matter with Skin Symptoms in Schoolchildren: A Panel Study in a Rural Area of Western Japan.

    PubMed

    Watanabe, Masanari; Noma, Hisashi; Kurai, Jun; Sano, Hiroyuki; Iwata, Kyoko; Hantan, Degejirihu; Tohda, Yuji; Shimizu, Eiji

    2017-03-13

    Numerous studies have unmasked the deleterious effects of particulate matter less than 2.5 μm (PM 2.5 ) on health. However, epidemiologic evidence focusing on the effects of PM 2.5 on skin health remains limited. An important aspect of Asian dust (AD) in relationship to health is the amount of PM 2.5 contained therein. Several studies have demonstrated that AD can aggravate skin symptoms. The current study aimed to investigate the effects of short-term exposure to PM 2.5 and AD particles on skin symptoms in schoolchildren. A total of 339 children recorded daily skin symptom scores during February 2015. Light detection and ranging were used to calculate AD particle size. Generalized estimating equation logistic regression analyses were used to estimate the associations among skin symptoms and the daily levels of PM 2.5 and AD particles. Increases in the levels of PM 2.5 and AD particles were not related to an increased risk of skin symptom events, with increases of 10.1 μg/m³ in PM 2.5 and 0.01 km -1 in AD particles changing odds ratios by 1.03 and 0.99, respectively. These results suggest that short-term exposure to PM 2.5 and AD does not impact skin symptoms in schoolchildren.

  3. 76 FR 53688 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-29

    ... Integrated Review Group, Behavioral Genetics and Epidemiology Study Section. Date: September 27, 2011. Time... Special Emphasis Panel, Collaborative: Behavioral Genetics and Epidemiology. Date: September 27, 2011..., Integrative and Molecular Gastroenterology Study Section. Date: October 3, 2011. Time: 8 a.m. to 7 p.m. Agenda...

  4. 76 FR 53479 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-26

    ...; Community-Level Health Promotion Study Section. Date: September 26-27, 2011. Time: 8:30 a.m. to 5 p.m...: Center for Scientific Review Special Emphasis Panel; Member Conflict: Cancer Biology and Genetics. Date....gov . Name of Committee: Cell Biology Integrated Review Group; Development--2 Study Section. Date...

  5. THE 1998 BALTIMORE PARTICULATE MATTER EPIDEMIOLOGY-EXPOSURE STUDY: PART 1 - COMPARISON OF AMBIENT, RESIDENTIAL OUTDOOR, INDOOR AND APARTMENT PARTICULATE MATTER MONITORING

    EPA Science Inventory

    A combined epidemiological-exposure panel study was conducted during the summer of 1998 in Baltimore, Maryland. The objectives of the exposure analysis component of the 28-day study were to investigate the statistical relationships between particulate matter (PM) and related co...

  6. 78 FR 28235 - National Cancer Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-14

    ... Basal- like Breast Cancer. Date: June 13, 2013. Time: 12:00 p.m. to 1:00 p.m. Agenda: To review and... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute... personal privacy. Name of Committee: National Cancer Institute Special Emphasis Panel, Novel Imaging Agents...

  7. 75 FR 39698 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-12

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel, Network Infrastructure for Aging Research. Date: July 20, 2010. Time: 12 p.m. to 4 p.m. Agenda: To review and evaluate...

  8. 75 FR 63497 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-15

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Genetic Determinants of Healthy Aging. Date: November 10, 2010. Time: 1 p.m. to 5 p.m. Agenda: To review and evaluate...

  9. 78 FR 70072 - Meeting of the Military Compensation and Retirement Modernization Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-22

    ... beneficiaries and other interested parties regarding pay, retirement, health benefits and quality of life... and education community representatives, and dining facilities, grocery and other quality of life... 12:30 p.m., Medical Services 3:00 p.m., Quality of Life Matters The Panel Testimony heard on both...

  10. 77 FR 12318 - National Eye Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-29

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Eye Institute... unwarranted invasion of personal privacy. Name of Committee: National Eye Institute Special Emphasis Panel; NEI Anterior Eye Disease. Date: March 19, 2012. Time: 1 p.m. to 2:30 p.m. Agenda: To review and...

  11. 75 FR 20853 - National Eye Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-21

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Eye Institute... unwarranted invasion of personal privacy. Name of Committee: National Eye Institute Special Emphasis Panel, Immunosuppression for Eye Diseases. Date: April 20, 2010. Time: 3 p.m. to 4 p.m. Agenda: To review and evaluate...

  12. 77 FR 67015 - National Cancer Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-08

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute... personal privacy. Name of Committee: National Cancer Institute Special Emphasis Panel NCI Omnibus and Cancer Therapy. Date: November 14-15, 2012. Time: 2:00 p.m. to 5:00 p.m. Agenda: To review and evaluate...

  13. 75 FR 44274 - National Cancer Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-28

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute... Cancer Institute Special Emphasis Panel, Nanotechnology Imaging and Sensing Platforms for Improved Diagnosis of Cancer. Date: August 31, 2010. Time: 12 p.m. to 1:30 p.m. Agenda: To review and evaluate...

  14. 76 FR 577 - National Cancer Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-05

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute... personal privacy. Name of Committee: National Cancer Institute Special Emphasis Panel; Therapeutic Strategies for Cancer. Date: February 2-4, 2011. Time: 3 p.m. to 5 p.m. Agenda: To review and evaluate grant...

  15. 75 FR 16816 - National Cancer Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-02

    ... personal privacy. Name of Committee: National Cancer Institute Special Emphasis Panel, NCI SPORE in Skin and Prostate Cancers. Date: June 15-16, 2010. Time: 4 p.m. to 5 p.m. Agenda: To review and evaluate... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute...

  16. 77 FR 56661 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-13

    ... Emphasis Panel; Member Conflict: Neurodevelopment, Plasticity, and Regeneration. Date: October 9, 2012... Bone, Function, Metabolism and Regeneration. Date: October 9, 2012. Time: 1:30 p.m. to 4 p.m. Agenda..., Bethesda, MD 20892, 301-435-1212, [email protected] . Name of Committee: Cell Biology Integrated Review...

  17. 77 FR 60478 - Proposal Review Panel for Computing Communication Foundations; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-03

    ... assess the progress of the EIC Award: 1029711, ``Collaborative Research: Mining Climate and Ecosystem Data'', and to provide advice and recommendations concerning further NSF support for the Center. AGENDA... answer sessions. 1 p.m.-8 p.m. Closed Draft report on education and research activities. Wednesday...

  18. 78 FR 66752 - National Human Genome Research Institute; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-06

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... National Human Genome Research Institute Special Emphasis Panel, October 15, 2013, 01:00 p.m. to October 15, 2013, 02:30 p.m., National Human Genome Research Institute, 5635 Fishers Lane, Suite 3055, Rockville...

  19. 77 FR 24725 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-25

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review... personal privacy. Name of Committee: Center for Scientific Review Special Emphasis Panel; Healthcare Delivery Methodologies Member Applications. Date: May 7, 2012. Time: 12 p.m. to 2 p.m. Agenda: To review...

  20. 76 FR 4092 - Fisheries of the South Atlantic and Gulf of Mexico; South Atlantic Fishery Management Council...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-24

    ... reports, and discuss methodologies for predicting future catch levels for use in amendment analyses. The...: February 15, 2011: 9 a.m.-5 p.m. and February 16, 2011: 9 a.m.-1 p.m. The SSC's Social and Economics Panel...

  1. 78 FR 55266 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-10

    ... Diseases and Nutrition. Date: October 22, 2013. Time: 8:00 a.m. to 4:00 p.m. Agenda: To review and evaluate... in Diabetic Ketoacidosis (U34) Date: October 21, 2013. Time: 9:30 a.m. to 11:30 a.m. Agenda: To... Panel; DDK-C Conflicts Date: October 22, 2013. Time: 4:00 p.m. to 6:00 p.m. Agenda: To review and...

  2. BAYESIAN HIERARCHICAL MODELING OF PERSONAL EXPOSURE TO PARTICULATE MATTER

    EPA Science Inventory

    In the US EPA's 1998 Baltimore Epidemiology-Exposure Panel Study, a group of 21 residents of a single building retirement community wore personal monitors recording personal fine particulate air pollution concentrations (PM2.5) for 27 days, while other monitors recorde...

  3. Ambient particulate air pollution, heart rate variability, and blood markers of inflammation in a panel of elderly subjects.

    PubMed Central

    Pope, C Arden; Hansen, Matthew L; Long, Russell W; Nielsen, Karen R; Eatough, Norman L; Wilson, William E; Eatough, Delbert J

    2004-01-01

    Epidemiologic studies report associations between particulate air pollution and cardiopulmonary morbidity and mortality. Although the underlying pathophysiologic mechanisms remain unclear, it has been hypothesized that altered autonomic function and pulmonary/systemic inflammation may play a role. In this study we explored the effects of air pollution on autonomic function measured by changes in heart rate variability (HRV) and blood markers of inflammation in a panel of 88 elderly subjects from three communities along the Wasatch Front in Utah. Subjects participated in multiple sessions of 24-hr ambulatory electrocardiographic monitoring and blood tests. Regression analysis was used to evaluate associations between fine particulate matter [aerodynamic diameter less than or equal to 2.5 microm (PM2.5)] and HRV, C-reactive protein (CRP), blood cell counts, and whole blood viscosity. A 100- microg/m3 increase in PM2.5 was associated with approximately a 35 (SE = 8)-msec decline in standard deviation of all normal R-R intervals (SDNN, a measure of overall HRV); a 42 (SE = 11)-msec decline in square root of the mean of the squared differences between adjacent normal R-R intervals (r-MSSD, an estimate of short-term components of HRV); and a 0.81 (SE = 0.17)-mg/dL increase in CRP. The PM2.5-HRV associations were reasonably consistent and statistically robust, but the CRP association dropped to 0.19 (SE = 0.10) after excluding the most influential subject. PM2.5 was not significantly associated with white or red blood cell counts, platelets, or whole-blood viscosity. Most short-term variability in temporal deviations of HRV and CRP was not explained by PM2.5; however, the small statistically significant associations that were observed suggest that exposure to PM2.5 may be one of multiple factors that influence HRV and CRP. PMID:14998750

  4. Beeswax as phase change material to improve solar panel’s performance

    NASA Astrophysics Data System (ADS)

    Thaib, R.; Rizal, S.; Riza, M.; Mahlia, T. M. I.; Rizal, T. A.

    2018-02-01

    One of the main obstacles faced during the operation of photovoltaic (PV) panels was overheating due to excessive solar radiation and high ambient temperatures. In this research, investigates the use of beeswax phase change materials (PCM) to maintain the temperature of the panels close to ambient. Solar panels used in this study has 839 mm length, 537 mm wide, and 50 mm thick, with maximum output power at 50 W. During the study, there were two solar panels was evaluated, one without phase change material while the other one was using beeswax phase change material. Solar panels were mounted at 15° slope. Variables observed was the temperature of solar panel’s surface, output voltage and current that produced by PV panels, wind speed around solar panels, and solar radiation. The observation was started at 07:00 am and ended at 06:00 pm. The research shows that maximum temperature of solar panels surface without phase change material is ranging between 46-49 °C, and electrical efficiency is about 7.2-8.8%. Meanwhile, for solar panels with beeswax phase change material, the maximum temperature solar panels surface is relatively low ranging between 33-34 °C, and its electrical efficiency seems to increase about 9.1-9.3%.

  5. USE OF CONTINUOUS NEPHELOMETER TO MEASURE PERSONAL EXPOSURE TO PARTICULATE MATTER DURING THE 1998 U.S. EPA BALTIMORE PANEL STUDY

    EPA Science Inventory

    Personal exposures to particulate matter (PM) have typically been measured using filter samplers worn by the participants in exposure studies. Personal filter samplers, however, are limited to providing average mass concentrations integrated over a 12- to 24-hour period due to ...

  6. 75 FR 20370 - National Cancer Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-19

    ... Special Emphasis Panel, Breast Cancer Biology. Date: May 20, 2010. Time: 8 a.m. to 5 p.m. Agenda: To... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute... Cancer Institute Special Emphasis Panel, Assay Systems for Drug Efficacy in Cancer Stem Cells. Date...

  7. 76 FR 77559 - Meeting of Humanities Panel

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-13

    ... THE NATIONAL FOUNDATION ON THE ARTS AND THE HUMANITIES Meeting of Humanities Panel AGENCY: The... world history for the EDSITEment Web site. EDSITEment is an on-line educational partnership between the... creation of content for world history on the Endowment's EDSITEment Web site. Agenda: 9 a.m. to 12 p.m...

  8. 78 FR 69940 - Open Meeting of the Taxpayer Advocacy Panel Notices and Correspondence Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-21

    ... Notices and Correspondence Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Notices and Correspondence... Correspondence Project Committee will be held Wednesday, December 11, 2013, at 12 p.m. Eastern Time via...

  9. 78 FR 15124 - Open Meeting of the Taxpayer Advocacy Panel Notices and Correspondence Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-08

    ... Notices and Correspondence Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Notices and Correspondence... Notices and Correspondence Project Committee will be held Wednesday, April 10, 2013, at 12 p.m. Eastern...

  10. 78 FR 56270 - Open Meeting of the Taxpayer Advocacy Panel Notices and Correspondence Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-12

    ... Notices and Correspondence Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of Meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Notices and Correspondence... Correspondence Project Committee will be held Wednesday, October 9, 2013, at 12 p.m. Eastern Time via...

  11. 78 FR 78516 - Open Meeting of the Taxpayer Advocacy Panel Notices and Correspondence Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-26

    ... Notices and Correspondence Project Committee AGENCY: Internal Revenue Service (IRS),Treasury. ACTION: Notice of Meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Notices and Correspondence... Correspondence Project Committee will be held Wednesday, January 22, 2014, at 12 p.m. Eastern Time via...

  12. 78 FR 64294 - Open Meeting of the Taxpayer Advocacy Panel Notices and Correspondence Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-28

    ... Notices and Correspondence Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Notices and Correspondence... Correspondence Project Committee will be held Wednesday, November 13, 2013, at 12 p.m. Eastern Time via...

  13. 78 FR 41194 - Open Meeting of the Taxpayer Advocacy Panel Notices and Correspondence Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-09

    ... Notices and Correspondence Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Notices and Correspondence... Correspondence Project Committee will be held Wednesday, August 14, 2013, at 12 p.m. Eastern Time via...

  14. 78 FR 48230 - Open Meeting of the Taxpayer Advocacy Panel Notices and Correspondence Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-07

    ... Notices and Correspondence Project Committee AGENCY: Internal Revenue Service (IRS) Treasury. ACTION: Notice of Meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Notices and Correspondence... Correspondence Project Committee will be held Wednesday, September 11, 2013, at 12 p.m. Eastern Time via...

  15. 75 FR 13769 - National Eye Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-23

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Eye Institute... unwarranted invasion of personal privacy. Name of Committee: National Eye Institute Special Emphasis Panel; National Eye Institute SBIR Special Emphasis Panel. Date: April 9, 2010. Time: 8:30 a.m. to 5 p.m. Agenda...

  16. 76 FR 63664 - Meetings of Humanities Panel

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-13

    ... NATIONAL FOUNDATION ON THE ARTS AND THE HUMANITIES Meetings of Humanities Panel AGENCY: The... assistance under the National Foundation on the Arts and the Humanities Act of 1965, as amended, including..., 2011. Time: 9 a.m. to 5 p.m. Location: Room 421. Program: This meeting will review applications for Art...

  17. 77 FR 21158 - Open Meeting of the Taxpayer Advocacy Panel Refund Processing Communications Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-09

    ... Refund Processing Communications Project Committee AGENCY: Internal Revenue Service (IRS), Treasury... Communications Project Committee will be conducted. The Taxpayer Advocacy Panel is soliciting public comments... Refund Processing Communications Project Committee will be held Thursday, May 03, 2012 at 2 p.m. Eastern...

  18. 78 FR 28946 - Open Meeting of the Taxpayer Advocacy Panel Taxpayer Communications Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-16

    ... Taxpayer Communications Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of Meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Taxpayer Communications Project... Taxpayer Communications Project Committee will be held Thursday, June 20, 2013 at 2:00 p.m. Eastern Time...

  19. 78 FR 22947 - Open Meeting of the Taxpayer Advocacy Panel Taxpayer Communications Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-17

    ... Taxpayer Communications Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Taxpayer Communications Project... Taxpayer Communications Project Committee will be held Thursday, May 16, 2013 at 2:00 p.m. Eastern Time via...

  20. 77 FR 5852 - Proposal Review Panel for Chemistry; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-06

    ... NATIONAL SCIENCE FOUNDATION Proposal Review Panel for Chemistry; Notice of Meeting In accordance with the Federal Advisory Committee Act (Pub. L. 92- 463, as amended), the National Science Foundation... and Computation for Chemistry Presentations. 11:45 a.m.-1 p.m. Closed--Executive Session, review and...

  1. 76 FR 12996 - Proposal Review Panel for Chemistry; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-09

    ... NATIONAL SCIENCE FOUNDATION Proposal Review Panel for Chemistry; Notice of Meeting In accordance... Awardees by NSF Division of Chemistry (CHE), 1191. Dates and Times: March 31, 2011; 8 a.m.-5:30 p.m. April... Director, Chemistry Centers Program, Division of Chemistry, Room 1055, National Science Foundation, 4201...

  2. 76 FR 6499 - Proposal Review Panel for Chemistry; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-04

    ... NATIONAL SCIENCE FOUNDATION Proposal Review Panel for Chemistry; Notice of Meeting In accordance... Awardees by NSF Division of Chemistry (1191). Dates and Times: February 17, 2011; 8 a.m.-6 p.m. February 18... Director, Chemistry Centers Program, Division of Chemistry, Room 1055, National Science Foundation, 4201...

  3. 75 FR 36661 - National Cancer Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-28

    ... Panel; Small Grants for Behavioral Research in Cancer Control. Date: July 21-22, 2010. Time: 7 p.m. to 5...: National Cancer Institute Special Emphasis Panel; Emerging Technologies for Cancer Research. Date...; 93.393, Cancer Cause and Prevention Research; 93.394, Cancer Detection and Diagnosis Research; 93.395...

  4. 78 FR 72902 - Center For Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-04

    ... Panel Member Conflict: Molecular and Cellular Neurodegeneration. Date: January 6, 2014. Time: 1:00 p.m... for Scientific Review Special Emphasis Panel, Member Conflict: Molecular and Cellular Neurodevelopment....306, Comparative Medicine; 93.333, Clinical Research; 93.306, 93.333, 93.337, 93.393-93.396, 93.837-93...

  5. 76 FR 52960 - National Cancer Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-24

    ... Emphasis Panel, Mechanisms of Cell Signaling in Cancer. Date: October 13-14, 2011. Time: 3 to 5 p.m. Agenda... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute... personal privacy. Name of Committee: National Cancer Institute Special Emphasis Panel, Discovery, Imaging...

  6. 78 FR 3500 - Open Meeting of the Taxpayer Advocacy Panel Notices and Correspondence Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-16

    ... Project Committee will be conducted. The Taxpayer Advocacy Panel is soliciting public comments, ideas, and... Correspondence Project Committee will be held Wednesday, February 13, 2013, at 12 p.m. Eastern Time via... Notices and Correspondence Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION...

  7. 77 FR 74921 - Open Meeting of the Taxpayer Advocacy Panel Notices and Correspondence Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-18

    ... Project Committee will be conducted. The Taxpayer Advocacy Panel is soliciting public comments, ideas, and... Correspondence Project Committee will be held Wednesday, January 9, 2013, at 12 p.m. Eastern Time via... Notices and Correspondence Project Committee AGENCY: Internal Revenue Service (IRS) Treasury. ACTION...

  8. 75 FR 71134 - National Institute of General Medical Sciences; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-22

    ... General Medical Sciences; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory... Sciences Special Emphasis Panel; Conference Grants Review. Date: December 13, 2010. Time: 1 p.m. to 6 p.m..., Office of Scientific Review, National Institute of General Medical Sciences, National Institutes of...

  9. 75 FR 35820 - National Institute of Biomedical Imaging and Bioengineering; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-23

    ... Imaging and Bioengineering Special Emphasis Panel Decision Support Systems and Comparative Effectiveness Research (ARRA). Date: July 23, 2010. Time: 12 p.m. to 5 p.m. Agenda: To review and evaluate grant... Assistance Program Nos. 93.701, ARRA Related Biomedical Research and Research Support Awards, National...

  10. 78 FR 66368 - National Institute on Aging; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-05

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... Aging Special Emphasis Panel, October 17, 2013, 12:00 p.m. to October 17, 2013, 05:00 p.m., National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892, which was...

  11. 78 FR 66373 - National Institute on Aging; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-05

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... Aging Special Emphasis Panel, October 16, 2013, 02:00 p.m. to October 16, 2013, 05:00 p.m., National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892, which was...

  12. 78 FR 20669 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-05

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Management of the Primate Aging Database Date: April 23, 2013. Time: 1:00 p.m. to 4:00 p.m. Agenda: To review and evaluate...

  13. 75 FR 67381 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-02

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel HIV, HAART and AGING. Date: November 23, 2010. Time: 1 p.m. to 5 p.m. Agenda: To review and evaluate grant applications...

  14. 78 FR 69432 - National Institute on Aging; Cancellation of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-19

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging; Cancellation of Meeting Notice is hereby given of the cancellation of the National Institute on Aging Special Emphasis Panel, December 18, 2013, 2:00 p.m. to December 18, 2013, 3:15 p.m., National Institute of Aging...

  15. 78 FR 66369 - National Institute on Aging; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-05

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... Aging Special Emphasis Panel, October 17, 2013, 12:00 p.m. to October 17, 2013, 04:00 p.m., National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892, which was...

  16. 75 FR 26260 - National Eye Institute; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-11

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Eye Institute; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Eye Institute Special Emphasis Panel, April 20, 2010, 3 p.m., to April 20, 2010, 4 p.m., National Eye Institute, 5635...

  17. 75 FR 51828 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-23

    ... unwarranted invasion of personal privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel; Heart Failure Clinical Trial. Date: September 3, 2010. Time: 1 p.m. to 3 p.m. Agenda: To... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Heart, Lung, and...

  18. 77 FR 15782 - National Cancer Institute Amended; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-16

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute Amended; Notice of Meeting Notice is hereby given of a change in the meeting of the National Cancer Institute Special Emphasis Panel, April 18, 2012, 1 p.m. to April 18, 2012, 5 p.m., National Institutes of...

  19. 78 FR 38355 - National Cancer Institute Amended; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-26

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute Amended; Notice of Meeting Notice is hereby given of a change in the meeting of the National Cancer Institute Special Emphasis Panel, July 08, 2013, 12:00 p.m. to July 08, 2013, 02:00 p.m., National Cancer...

  20. 75 FR 11896 - National Cancer Institute; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-12

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Cancer Institute Special Emphasis Panel, March 25, 2010, 12:30 p.m. to March 25, 2010, 5:30 p.m., National...

  1. 77 FR 13133 - National Cancer Institute; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-05

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Cancer Institute Special Emphasis Panel, March 7, 2012, 12:15 p.m. to March 7, 2012, 3:15 p.m., National Institutes...

  2. 76 FR 37134 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-24

    ... Blood Institute Special Emphasis Panel, NHLBI Career Enhancement Grants for Stem Cell Research. Date..., Short Term Research Training Program. Date: July 20, 2011. Time: 1 p.m. to 4 p.m. Agenda: To review and... . (Catalogue of Federal Domestic Assistance Program Nos. 93.233, National Center for Sleep Disorders Research...

  3. 78 FR 9708 - National Institute on Aging Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-11

    ... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Comparative Physiology of Aging. Date: March 14, 2013. Time: 12:30 p.m. to 3:30 p.m. Agenda: To review and evaluate grant... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging...

  4. 77 FR 3454 - Department of Defense Task Force on the Care, Management, and Transition of Recovering Wounded...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-24

    ... Members Post-Operational Deployment, Dr. Richard R. Bannick 9:30-9:45 a.m. Break 9:45-10:45 a.m. OSD... 10 a.m.-12 p.m. Panel on Evidence-Based Treatment Modalities for PTSD (Program 12:00-1 p.m. Lunch 1...

  5. 77 FR 66623 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-06

    ... personal privacy. Name of Committee: Center for Scientific Review Special Emphasis Panel; Program Project: Mass Spectrometry Resource. Date: November 26-28, 2012. Time: 7:00 p.m. to 12:00 p.m. Agenda: To review... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review...

  6. 75 FR 1754 - Gulf of Mexico Fishery Management Council; Public Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-13

    ...; Spiny Lobster/ Stone Crab Management; Red Drum; Habitat Protection; Coastal Migratory Pelagics (Mackerel... the SEDAR meetings for Spiny Lobster, Yellowedge Grouper and Tilefish and Greater Amberjack. 9:20 a.m... Panel meeting. 4:45 p.m. - 5:45 p.m. - The Spiny Lobster/Stone Crab Committee will discuss the Options...

  7. 78 FR 17218 - National Institute of Allergy and Infectious Diseases; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-20

    ... Allergy and Infectious Diseases; Notice of Closed Meeting Pursuant to section 10(d) of the Federal... Infectious Diseases Special Emphasis Panel, ``Limited Competition: Collaborative Partnership to Advance Global Biomedical Research Programs (U01).'' Date: April 12, 2013. Time: 1:00 p.m. to 3:00 p.m. Agenda...

  8. 76 FR 55691 - National Institute on Aging Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-08

    ... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Aminergic Function and Brain Aging II. Date: October 21, 2011. Time: 12:30 p.m. to 4:30 p.m. Agenda: To review and... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging...

  9. 75 FR 50771 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-17

    ... Institute Special Emphasis Panel; NHLBI Nanotechnology Administrative Centers Contract Review. Date: August 20, 2010. Time: 1 p.m. to 2 p.m. Agenda: To review and evaluate contract proposals. Place: National...: Shelley S Sehnert, PhD, Scientific Review Officer, Review Branch/DERA, National Heart, Lung, and Blood...

  10. 76 FR 10038 - National Institute of General Medical Sciences; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-23

    ... Sciences Special Emphasis Panel, PSI Biology Meeting. Date: March 11, 2011. Time: 1 p.m. to 5 p.m. Agenda... Nos. 93.375, Minority Biomedical Research Support; 93.821, Cell Biology and Biophysics Research; 93... Biology Research; 93.88, Minority Access to Research Careers; 93.96, Special Minority Initiatives...

  11. 77 FR 26301 - National Cancer Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-03

    ....396, Cancer Biology Research; 93.397, Cancer Centers Support; 93.398, Cancer Research Manpower; 93.399..., MD 20892 (Telephone Conference Call). Contact Person: Virginia P. Wray, Ph.D., Deputy Chief, Research... Special Emphasis Panel; Cell-Based Imaging. Date: June 19, 2012. Time: 1:00 p.m. to 4:00 p.m. Agenda: To...

  12. 75 FR 35075 - National Center for Complementary & Alternative Medicine; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-21

    ... Complementary & Alternative Medicine; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory... Alternative Medicine Special Emphasis Panel; PCCTR (U 19). Date: July 15-16, 2010. Time: 5 p.m. to 5 p.m..., Office of Scientific Review, National Center for Complementary, & Alternative Medicine, NIH, 6707...

  13. 75 FR 16815 - National Institute on Drug Abuse; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-02

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  14. 76 FR 28236 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-16

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... Emphasis Panel, Oxidative Stress and Aging. Date: July 13, 2011. Time: 12 p.m. to 4 p.m. Agenda: To review... Domestic Assistance Program Nos. 93.866, Aging Research, National Institutes of Health, HHS) Dated: May 10...

  15. 78 FR 48179 - National Institute of Neurological Disorders and Stroke; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-07

    ... Disorders and Stroke Special Emphasis Panel; Review Career Development Awards. Date: August 14, 2013. Time: 2:00 p.m. to 3:00 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes...). Contact Person: Raul A. Saavedra, Ph.D., Scientific Review Officer, Scientific Review Branch, Division of...

  16. 77 FR 71430 - National Institute of General Medical Sciences; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-30

    ... Sciences Special Emphasis Panel; Review of P01 Grant Applications- Vitamin D. Date: December 10, 2012. Time: 1:00 p.m. to 3:00 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes... Call). Contact Person: Lisa Dunbar, Ph.D., Scientific Review Officer, Office of Scientific Review...

  17. 77 FR 58204 - Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-19

    ..., 2012, from 1 p.m. to 3 p.m. Eastern time. Meeting Details: The teleconference call-in number is toll... Fish Commission (NPAFC) will meet on the date and time noted above. The panel consists of members from...-12; St. Petersburg, Russia); and (2) logistics for the U.S. Section at the NPAFC meeting. Background...

  18. 77 FR 6857 - Pipeline Safety: Notice of Public Meetings on Improving Pipeline Leak Detection System...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-09

    ... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration [Docket ID... installed to lessen the volume of natural gas and hazardous liquid released during catastrophic pipeline... p.m. Panel 3: Considerations for Natural Gas Pipeline Leak Detection Systems 3:30 p.m. Break 3:45 p...

  19. 77 FR 48552 - Meetings of Humanities Panel

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-14

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  20. 76 FR 5390 - National Human Genome Research Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-31

    ... Research Institute; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee... unwarranted invasion of personal privacy. Place: National Human Genome Research Institute Special Emphasis Panel; NHGRI Sample Repository for Human Genetic Research. Date: March 3, 2011. Time: 1 p.m. to 2 p.m...

  1. IDENTIFICATION OF EMERGING SUB-POPULATIONS SUSCEPTIBLE TO ADVERSE HEALTH EFFECTS ASSOCIATED WITH AIR PARTICULATE EXPOSURE

    EPA Science Inventory

    The overall weight of evidence from panel, clinical, and toxicological studies has demonstrated the ability of ambient air particulate matter (PM) exposure to induce a variety of extra-pulmonary effects ranging from alterations in hematological parameters to cardiac function. Alt...

  2. Short-term metal particulate exposures decrease cardiac acceleration and deceleration capacities in welders: a repeated-measures panel study.

    PubMed

    Umukoro, Peter E; Cavallari, Jennifer M; Fang, Shona C; Lu, Chensheng; Lin, Xihong; Mittleman, Murray A; Christiani, David C

    2016-02-01

    Acceleration (AC) and deceleration (DC) capacities measure heart rate variability during speeding up and slowing down of the heart, respectively. We investigated associations between AC and DC with occupational short-term metal PM2.5 exposures. A panel of 48 male welders had particulate matter less than 2.5 microns in diameter (PM2.5) exposure measurements over 4-6 h repeated over 5 sampling periods between January 2010 and June 2012. We simultaneously obtained continuous recordings of digital ECG using a Holter monitor. We analysed ECG data in the time domain to obtain hourly AC and DC. Linear mixed models were used to assess the associations between hourly PM2.5 exposure and each of hourly AC and DC, controlling for age, smoking status, active smoking, exposure to secondhand smoke, season/time of day when ECG reading was obtained and baseline AC or DC. We also ran lagged exposure response models for each successive hour up to 3 h after onset of exposure. Mean (SD) shift PM2.5 exposure during welding was 0.47 (0.43) mg/m(3). Significant exposure-response associations were found for AC and DC with increased PM2.5 exposure. In our adjusted models without any lag between exposure and response, a 1 mg/m(3) increase of PM2.5 was associated with a decrease of 1.46 (95% CI 1.00 to 1.92) ms in AC and a decrease of 1.00 (95% CI 0.53 to 1.46) ms in DC. The effect of PM2.5 on AC and DC was maximal immediately postexposure and lasted 1 h following exposure. There are short-term effects of metal particulates on AC and DC. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  3. Analysis of influential factors on haze pollution in China

    NASA Astrophysics Data System (ADS)

    Liu, Xiao-Hong; Jiang, Keshen

    2018-05-01

    This study tests the hypothesis of Environmental Kuznets Curve (EKC) between PM10 concentrations and economic growth and analyzes the influential factors of PM10 concentrations from the economic perspective by using the panel data on the PM10 concentrations of 30 provinces from 2003 to 2015 in China. Results of the regression estimation from the fully modified OLS (FMOLS) method show that a relationship characterized by an inverted U-shaped curve is observed between PM10 concentrations and gross domestic product (GDP) per capita and that an EKC exists in China’s haze pollution problem. PM10 concentrations have the most sensitive response to GDP. The elastic coefficients of the possession of civilian vehicles, urbanization and trade openness are positive values. More importantly, the elastic coefficient of the tertiary industry proportion is less than 0. Increase in the proportion of tertiary industry can effectively alleviate China’s problem on haze pollution. Lastly, relevant countermeasures and suggestions are presented.

  4. Chemical constituents and sources of ambient particulate air pollution and biomarkers of endothelial function in a panel of healthy adults in Beijing, China.

    PubMed

    Wu, Shaowei; Yang, Di; Pan, Lu; Shan, Jiao; Li, Hongyu; Wei, Hongying; Wang, Bin; Huang, Jing; Baccarelli, Andrea A; Shima, Masayuki; Deng, Furong; Guo, Xinbiao

    2016-08-01

    Exposure to ambient air pollution has been associated with endothelial dysfunction as reflected by short-term alterations in circulating biomarkers, but the chemical constituents and pollution sources behind the association has been unclear. We investigated the associations between various ambient air pollutants including gases and 31 chemical constituents and seven sources of fine particles (PM2.5) and biomarkers of endothelial function, including endothelin-1 (ET-1), E-selectin, soluble intercellular adhesion molecule 1 (ICAM-1) and vascular cell adhesion molecule 1 (VCAM-1), based on 462 repeated measurements in a panel of 40 college students who were followed for three study periods before and after relocating from a suburban area to an urban area in Beijing, China in 2010-2011. Air pollution data were obtained from central air-monitoring stations. Linear mixed-effects models were used to estimate the changes in biomarkers associated with exposures. Total PM2.5 mass showed few appreciable associations with examined biomarkers. However, several PM2.5 constituents and related sources showed significant associations with examined biomarkers. PM2.5 from dust/soil and several crustal and transition metals, including strontium, iron, titanium, cobalt and magnesium, were significantly associated with increases in ET-1 at 1-day average; manganese and potassium were significantly associated with increases in ICAM-1 at 2-day average; and PM2.5 from industry and metal cadmium were significantly associated with decreases in VCAM-1 at 1-day average. In addition, carbon monoxide was significantly associated with increasing ICAM-1 at 1-day and 2-day averages, whereas nitric oxide was significantly associated with decreasing ICAM-1 at 1-day and 3-day averages. Our results suggest that certain PM2.5 metal constituents were more closely associated with circulating biomarkers of endothelial function than PM2.5, and therefore highlight the research necessity to examine pollution chemical constituents in future studies. Copyright © 2016 Elsevier B.V. All rights reserved.

  5. 77 FR 61770 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-11

    ... commercial property such as patentable material, and personal information concerning individuals associated... personal privacy. Name of Committee: Center for Scientific Review Special Emphasis Panel; Cancer...: Multidisciplinary Studies of HIV/AIDS and Aging. Date: November 9, 2012. Time: 10 a.m. to 6 p.m. Agenda: To review...

  6. 77 FR 51544 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-24

    ... Community Influences on Health Behavior. Date: September 20-21, 2012. Time: 8 a.m. to 5 p.m. Agenda: To... Clinical Integrated Review Group Drug Discovery and Molecular Pharmacology Study Section. Date: September... for Scientific Review Special Emphasis Panel Member Conflict: Adult and Child Psychopathology and...

  7. Effects of Exposure Measurement on Particle Matter Epidemiology: A Simulation Using Data from a Panel Study in Baltimore MD

    EPA Science Inventory

    Ascertaining the true risk associated with exposure to particulate matter (PM) is difficult, given the fact that pollutant components are frequently correlated with each other and with other gaseous pollutants; relationships between ambient concentrations and personal exposures a...

  8. Idiopathic inflammatory myopathies in adults: A comparative study of Bohan and Peter and European Neuromuscular Center 2004 criteria.

    PubMed

    Challa, Sundaram; Jakati, Saumya; Uppin, Megha S; Kannan, Meena A; Liza, Rajasekhar; Murthy Jagarlapudi, M K

    2018-01-01

    Bohan and Peter criteria are widely used for the diagnosis of idiopathic inflammatory myopathies (IIMs). Recently, European Neuromuscular Center (ENMC) formulated criteria to identify subgroups of IIMs. To compare the two diagnostic criteria in adult IIMs. This was a retrospective review of case records of histologically confirmed IIMs in adults between January 2014 and May 2015. Both the Bohan and Peter, and ENMC 2004 criteria were applied in the same group of patients to subgroup the IIMs. Muscle biopsy was evaluated in all the four domains: muscle fiber, inflammatory, connective tissue, and vascular, with the basic panel of histological stains. Sporadic inclusion body myositis (s-IBM) was diagnosed using ENMC IBM diagnostic research criteria 2011. During the study period, 69 patients fulfilled the ENMC criteria for IIMs including 16 patients with s-IBM. The subgrouping as per the ENMC criteria (53) was: dermatomyositis (DM) in 30; polymyositis (PM) in 2; immune-mediated necrotizing myopathy (IMNM) in 9; and nonspecific myositis (NM) in 12 patients, whereas subgrouping by the Bohan and Peter criteria was DM in 9 and PM with and without connective tissue disease (CTD) in 26 patients only. There was underdiagnosis of DM, as perifascicular atrophy is not recognized as a diagnostic histological feature, and overdiagnosis of PM with and without CTD due to poor characterization of histological features in PM by the Bohan and Peter criteria. Systematic evaluation of muscle biopsy according to the ENMC criteria with basic panel of histochemical stains improved the diagnostic yield of IIM significantly when compared to the Bohan and Peter criteria.

  9. THE LONG-TERM DYNAMICS OF RACIAL/ETHNIC INEQUALITY IN NEIGHBORHOOD AIR POLLUTION EXPOSURE, 1990-2009.

    PubMed

    Kravitz-Wirtz, Nicole; Crowder, Kyle; Hajat, Anjum; Sass, Victoria

    2016-01-01

    Research examining racial/ethnic disparities in pollution exposure often relies on cross-sectional data. These analyses are largely insensitive to exposure trends and rarely account for broader contextual dynamics. To provide a more comprehensive assessment of racial-environmental inequality over time, we combine the 1990 to 2009 waves of the Panel Study of Income Dynamics (PSID) with spatially- and temporally-resolved measures of nitrogen dioxide (NO 2 ) and particulate matter (PM 2.5 and PM 10 ) in respondents' neighborhoods, as well as census data on the characteristics of respondents' metropolitan areas. Results based on multilevel repeated measures models indicate that Blacks and Latinos are, on average, more likely to be exposed to higher levels of NO 2 , PM 2.5 , and PM 10 than Whites. Despite nationwide declines in levels of pollution over time, racial and ethnic disparities persist and cannot be fully explained by individual-, household-, or metropolitan-level factors.

  10. 77 FR 40410 - Open Meeting of Taxpayer Advocacy Panel Taxpayer Burden Reduction Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-09

    ... Taxpayer Burden Reduction Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION... Project Committee will be conducted. The Taxpayer Advocacy Panel is soliciting public comments, ideas and... Reduction Project Committee will be held Wednesday, August 15, 2012, at 2:30 p.m. Eastern Time via telephone...

  11. 77 FR 30591 - Open Meeting of the Taxpayer Advocacy Panel Tax Forms and Publications Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-23

    ... Tax Forms and Publications Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION... Project Committee will be conducted. The Taxpayer Advocacy Panel is soliciting public comments, ideas and... Publications Project Committee will be held Wednesday, June 13, 2012, at 2:00 p.m. Eastern Time via telephone...

  12. 77 FR 40411 - Open Meeting of the Taxpayer Advocacy Panel Tax Forms and Publications Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-09

    ... Tax Forms and Publications Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION... Project Committee will be conducted. The Taxpayer Advocacy Panel is soliciting public comments, ideas and... Publications Project Committee will be held Wednesday, August 8, 2012, at 2:00 p.m. Eastern Time via telephone...

  13. 76 FR 32020 - Open Meeting of the Taxpayer Advocacy Panel Tax Forms and Publications Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-02

    ... Tax Forms and Publications Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION... Project Committee will be conducted. The Taxpayer Advocacy Panel is soliciting public comments, ideas and... Publications Project Committee will be held Tuesday, July 12, 2011, at 2 p.m. Eastern Time via telephone...

  14. 77 FR 2612 - Open Meeting of the Taxpayer Advocacy Panel Tax Forms and Publications Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-18

    ... Tax Forms and Publications Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION... Project Committee will be conducted. The Taxpayer Advocacy Panel is soliciting public comments, ideas and... Tax Forms and Publications Project Committee will be held Wednesday, February 8, 2012, at 2 p.m...

  15. 78 FR 78516 - Open Meeting of the Taxpayer Advocacy Panel Tax Forms and Publications Project Committee.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-26

    ... Tax Forms and Publications Project Committee. AGENCY: Internal Revenue Service (IRS), Treasury. ACTION... Project Committee will be conducted. The Taxpayer Advocacy Panel is soliciting public comments, ideas and... and Publications Project Committee will be held Wednesday, January 15, 2014 at 2:00 p.m. Eastern Time...

  16. 75 FR 4830 - National Institute of Diabetes and Digestive and Kidney Diseases;

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-29

    ... Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings Pursuant to section 10(d) of the... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel. Predictors of Genitourinary Disorders... Digestive and Kidney Diseases Special Emphasis Panel; Small Grant Program. Date: March 12, 2010. Time: 2 p.m...

  17. 76 FR 63311 - Center for Scientific Review Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-12

    ... Panel PAR-10-018: Accelerating the Pace of Drug Abuse Research Using Existing Epidemiology, Prevention, and Treatment Research Data. Date:November 1-2, 2011 Time: 10 a.m. to 5 p.m. Agenda: To review and... Scientific Review Special Emphasis Panel; Small Business: Orthopedic and Skeletal Biology. Date: November 7...

  18. 76 FR 30734 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-26

    ...: Sensory, Motor, and Cognitive Neuroscience. Date: June 30-July 1, 2011. Time: 8 a.m. to 5 p.m. Agenda: To... Panel, Fellowships: Biophysical and Physiological Neuroscience. Date: June 23-24, 2011. Time: 8 a.m. to... Scientific Review Special Emphasis Panel, Fellowships: Brain Disorders and Related Neuroscience. Date: June...

  19. 76 FR 2196 - Open Meeting of the Taxpayer Advocacy Panel Volunteer Income Tax Assistance Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-12

    ... Volunteer Income Tax Assistance Project Committee AGENCY: Internal Revenue Service (IRS) Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Volunteer Income Tax... Volunteer Income Tax Assistance Project Committee will be held Tuesday, February 8, 2011, at 2 p.m. Eastern...

  20. 76 FR 37197 - Open Meeting of the Taxpayer Advocacy Panel Volunteer Income Tax Assistance Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-24

    ... Volunteer Income Tax Assistance Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Volunteer Income Tax... Volunteer Income Tax Assistance Project Committee will be held Tuesday, August 9, 2011, 2 p.m. Eastern Time...

  1. 76 FR 32021 - Open meeting of the Taxpayer Advocacy Panel Volunteer Income Tax Assistance Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-02

    ... Volunteer Income Tax Assistance Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of Meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Volunteer Income Tax... Volunteer Income Tax Assistance Project Committee will be held Tuesday, July 12, 2011, 2 p.m. Eastern Time...

  2. 76 FR 6189 - Open Meeting of the Taxpayer Advocacy Panel Volunteer Income Tax Assistance Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-03

    ... Volunteer Income Tax Assistance Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Volunteer Income Tax... Volunteer Income Tax Assistance Project Committee will be held Tuesday, March 8, 2011, at 2 p.m., Eastern...

  3. 76 FR 22171 - Open Meeting of the Taxpayer Advocacy Panel Volunteer Income Tax Assistance Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-20

    ... Volunteer Income Tax Assistance Project Committee AGENCY: Internal Revenue Service (IRS) Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Volunteer Income Tax... Volunteer Income Tax Assistance Project Committee will be held Tuesday, June 14, 2011, 2 p.m. Eastern Time...

  4. 77 FR 61053 - Open Meeting of the Taxpayer Advocacy Panel Tax Forms and Publications Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-05

    ... Tax Forms and Publications Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Tax Forms and Publications... and Publications Project Committee will be held Wednesday, November 14, 2012, at 2:00 p.m. Eastern...

  5. 76 FR 10945 - Open Meeting of the Taxpayer Advocacy Panel Tax Forms and Publications Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-28

    ... Tax Forms and Publications Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Tax Forms and Publications... Publications Project Committee will be held Tuesday, April 12, 2011, at 2 p.m., Eastern Time via telephone...

  6. 76 FR 22171 - Open Meeting of the Taxpayer Advocacy Panel Tax Forms and Publications Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-20

    ... Tax Forms and Publications Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Tax Forms and Publications... Publications Project Committee will be held Tuesday, June 14, 2011, at 2 p.m. Eastern Time via telephone...

  7. 76 FR 13195 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-10

    ...: Center for Scientific Review Special Emphasis Panel; Program Project: Presynaptic Mechanisms of Neural...: AIDS/HIV Innovative Research Applications. Date: March 30, 2011. Time: 11 a.m. to 7 p.m. Agenda: To... Special Emphasis Panel; Program Project: Mitochondrial Metabolism. Date: April 4-5, 2011. Time: 8 a.m. to...

  8. 75 FR 54161 - National Center for Complementary and Alternative Medicine; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-03

    ... Complementary and Alternative Medicine; Notice of Closed Meeting Pursuant to section 10(d) of the Federal... Alternative Medicine Special Emphasis Panel; NCCAM Education Panel. Date: October 25-26, 2010. Time: 2 p.m. to... Alternative Medicine, National Institutes of Health, HHS) Dated: August 30, 2010. Jennifer S. Spaeth, Director...

  9. 77 FR 39246 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-02

    ... Competitive Revision Applications for Research Relevant to the Family Smoking Prevention and Tobacco [email protected] . Name of Committee: Center for Scientific Review Special Emphasis Panel; Member Conflict... Panel; Member Conflict: AIDS and AIDS Related Research. Date: July 30-31, 2012. Time: 10 a.m. to 5 p.m...

  10. 76 FR 61720 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-05

    ....nih.gov . Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel, Genomic... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Heart, Lung, and... Institute Special Emphasis Panel, NHLBI Cardiovascular Outcomes. Date: October 24, 2011. Time: 1 p.m. to 3 p...

  11. 76 FR 33322 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-08

    ... Scientific Review Special Emphasis Panel, Member Conflict: Cancer Therapeutics. Date: June 29, 2011. Time: 1... . Name of Committee: Center for Scientific Review Special Emphasis Panel, Small Business: Cancer Diagnostics and Treatments. Date: July 12-13, 2011. Time: 10 a.m. to 6 p.m. Agenda: To review and evaluate...

  12. 76 FR 10941 - Open Meeting of the Taxpayer Advocacy Panel Taxpayer Assistance Center Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-28

    ... Project Committee will be conducted. The Taxpayer Advocacy Panel is soliciting public comments, ideas, and... Taxpayer Assistance Center Project Committee will be held Tuesday, April 26, 2011, at 2 p.m., Central Time... Taxpayer Assistance Center Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION...

  13. 75 FR 66113 - National Institute of Mental Health; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-27

    ... Emphasis Panel; NRSA Institutional Research Training (T32). Date: November 17, 2010. Time: 8 a.m. to 5 p.m... Institute of Mental Health Special Emphasis Panel; Novel NeuroAIDS Therapeutics. Date: November 22, 2010... Research Service Awards for Research Training, National Institutes of Health, HHS) Dated: October 20, 2010...

  14. 75 FR 47349 - Open Meeting of the Taxpayer Advocacy Panel Earned Income Tax Credit Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-05

    ... Earned Income Tax Credit Project Committee AGENCY: Internal Revenue Service (IRS), Treasury ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Earned Income Tax Credit... Income Tax Credit Project Committee will be held Wednesday, September 22, 2010, at 1 p.m. Eastern Time...

  15. 78 FR 25101 - Proposal Review Panel for Physics, Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-29

    ... NATIONAL SCIENCE FOUNDATION Proposal Review Panel for Physics, Notice of Meeting In accordance... Physics, 1208 Date and Time: Tuesday, April 30, 2013; 8:00 a.m.-6:00 p.m., Wednesday, May 1, 2013, 8:00 a... Meeting: Partially Closed. Contact Person: Mark Coles, Director of Large Facilities, Division of Physics...

  16. 77 FR 51032 - National Cancer Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-23

    ... personal privacy. Name of Committee: National Cancer Institute Special Emphasis Panel, NCI Program Project... Cancer Institute Special Emphasis Panel, NCI Program Project Meeting III. Date: October 10-11, 2012. Time... Project Meeting IV. Date: October 15-16, 2012. Time: 8:00 a.m. to 5:00 p.m. Agenda: To review and evaluate...

  17. 76 FR 77892 - Open Meeting of the Taxpayer Advocacy Panel Tax Forms and Publications Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-14

    ... Tax Forms and Publications Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Tax Forms and Publications... Tax Forms and Publications Project Committee will be held Wednesday, January 11, 2012, at 2 p.m...

  18. A panel study of occupational exposure to fine particulate matter and changes in DNA methylation over a single workday and years worked in boilermaker welders

    PubMed Central

    2013-01-01

    Background Exposure to pollutants including metals and particulate air pollution can alter DNA methylation. Yet little is known about intra-individual changes in DNA methylation over time in relationship to environmental exposures. Therefore, we evaluated the effects of acute- and chronic metal-rich PM2.5 exposures on DNA methylation. Methods Thirty-eight male boilermaker welders participated in a panel study for a total of 54 person days. Whole blood was collected prior to any welding activities (pre-shift) and immediately after the exposure period (post-shift). The percentage of methylated cytosines (%mC) in LINE-1, Alu, and inducible nitric oxide synthase gene (iNOS) were quantified using pyrosequencing. Personal PM2.5 (particulate matter with an aerodynamic diameter ≤ 2.5 μm) was measured over the work-shift. A questionnaire assessed job history and years worked as a boilermaker. Linear mixed models with repeated measures evaluated associations between DNA methylation, PM2.5 concentration (acute exposure), and years worked as a boilermaker (chronic exposure). Results PM2.5 exposure was associated with increased methylation in the promoter region of the iNOS gene (β = 0.25, SE: 0.11, p-value = 0.04). Additionally, the number of years worked as a boilermaker was associated with increased iNOS methylation (β = 0.03, SE: 0.01, p-value = 0.03). No associations were observed for Alu or LINE-1. Conclusions Acute and chronic exposure to PM2.5 generated from welding activities was associated with a modest change in DNA methylation of the iNOS gene. Future studies are needed to confirm this association and determine if the observed small increase in iNOS methylation are associated with changes in NO production or any adverse health effect. PMID:23758843

  19. 77 FR 63843 - National Institute on Drug Abuse; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-17

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Amended Notice of Meeting Notice is hereby given of changes in the meeting of the National Institute on Drug Abuse Special Emphasis Panel, October 2, 2012, 1:00 p.m. to October 2, 2012, 4:00 p.m...

  20. 75 FR 25277 - National Institute on Drug Abuse; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-07

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Institute on Drug Abuse Special Emphasis Panel, May 11, 2010, 1:30 p.m. to May 11, 2010, 3 p.m., National...

  1. 78 FR 49550 - Meetings of Humanities Panel

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-14

    ... Division of Education Programs. 2. Date: September 09, 2013. Time: 8:30 a.m. to 5:00 p.m. Room: 421. This... Initiatives at Tribal Colleges and Universities grant program, submitted to the Division of Education Programs... Division of Education Programs. 6. Date: September 12, 2013. Time: 8:30 a.m. to 5:00 p.m. Room: 421. This...

  2. 76 FR 12744 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-08

    ... Institute Special Emphasis Panel; Inflammation and Cardiovascular Disease. Date: March 24, 2011. Time: 9 a.m... Disease. Date: March 30, 2011. Time: 1 p.m. to 3 p.m. Agenda: To review and evaluate grant applications..., National Center for Sleep Disorders Research; 93.837, Heart and Vascular Diseases Research; 93.838, Lung...

  3. 77 FR 28393 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-14

    ... review.'' Contact Person for More Information: Jane Suen, Dr.P.H., M.S., Scientific Review Officer, CDC... Disease Control and Prevention (CDC) announces the aforementioned meeting: Time and Date: 12:00 p.m.-4:00 p.m., June 14, 2012 (Closed). Place: Teleconference. Status: The meeting will be closed to the...

  4. 75 FR 7484 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-19

    ... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d...: National Institute of Child Health and Human Development Special Emphasis Panel; Changing Parental Relationships and Child Well-Being. Date: March 5, 2010. Time: 1 p.m. to 4 p.m. Agenda: To review and evaluate...

  5. 76 FR 26736 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-09

    ... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel, Systematic Review of Neonatal Medicine. Date: May 23, 2011. Time: 1 p.m. to 3 p.m. Agenda: To review and evaluate grant applications...

  6. 78 FR 31570 - National Cancer Institute: Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-24

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute: Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Cancer Institute Special Emphasis Panel, June 20, 2013, 03:00 p.m. to June 21, 2013, 06:00 p.m., Hilton Washington/Rockville, 1750 Rockville Pike, Rockville,...

  7. 75 FR 65498 - National Center for Complementary & Alternative Medicine; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-25

    ... Complementary & Alternative Medicine; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory... Alternative Medicine Special Emphasis Panel, Type 3 P01s. Date: November 16, 2010. Time: 2 p.m. to 3:30 p.m..., Research and Training in Complementary and Alternative Medicine, National Institutes of Health, HHS) Dated...

  8. 77 FR 2737 - Center for Scientific Review; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-19

    ... Panel; Drug Discovery for the Nervous System. Date: January 27, 2012. Time: 1 p.m. to 3 p.m. Agenda: To... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U...

  9. 78 FR 16274 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-14

    ...), Title 5 U.S.C., as amended. The contract proposals and the discussions could disclose confidential trade... individuals associated with the contract proposals, the disclosure of which would constitute a clearly... Emphasis Panel SBIR Pediatric Vascular Stents. Date: April 4, 2013. Time: 1:00 p.m. to 4:00 p.m. Agenda: To...

  10. 78 FR 64958 - National Institute on Drug Abuse; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-30

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Institute on Drug Abuse Special Emphasis Panel, October 15, 2013, 2:00 p.m. to October 16, 2013, 1:00 p.m...

  11. 76 FR 22407 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-21

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U... Panel; Aging and Mobility. Date: May 12, 2011. Time: 2 p.m. to 6 p.m. Agenda: To review and evaluate...

  12. 78 FR 40486 - National Institute of Arthritis and Musculoskeletal and Skin Diseases; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-05

    ... Arthritis and Musculoskeletal and Skin Diseases; Notice of Closed Meeting Pursuant to section 10(d) of the... Arthritis and Musculoskeletal and Skin Diseases Special Emphasis Panel; Arthritis and Musculoskeletal and Skin Diseases Clinical Trials Conflict Review Meeting. Date: July 26, 2013. Time: 1:00 p.m. to 4:00 p.m...

  13. 78 FR 64228 - National Cancer Institute; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-28

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Cancer Institute Special Emphasis Panel, October 16, 2013, 04:00 p.m. to October 17, 2013, 05:00 p.m., Bethesda North Marriott Hotel & Conference Center, 5701...

  14. 78 FR 64228 - National Cancer Institute; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-28

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Cancer Institute Special Emphasis Panel, October 17, 2013, 05:00 p.m. to October 18, 2013, 06:00 p.m., Bethesda North Marriott Hotel & Conference Center, 5701...

  15. 78 FR 66374 - National Cancer Institute; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-05

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Cancer Institute Special Emphasis Panel, October 15, 2013, 4:00 p.m. to October 16, 2013, 5:00 p.m., Hilton Washington/Rockville, 1750 Rockville Pike,...

  16. 78 FR 58322 - National Cancer Institute; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-23

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Cancer Institute Special Emphasis Panel, November 06, 2013, 06:30 p.m. to November 07, 2013, 04:00 p.m., Hilton Washington/Rockville, 1750 Rockville Pike,...

  17. 78 FR 58323 - National Cancer Institute; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-23

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Cancer Institute Special Emphasis Panel, October 17, 2013, 4:00 p.m. to October 18, 2013, 06:00 p.m., Bethesda North Marriott Hotel & Conference Center, 5701...

  18. 78 FR 64958 - National Cancer Institute; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-30

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Cancer Institute Special Emphasis Panel, October 15, 2013, 4:00 p.m. to October 16, 2013, 5:00 p.m., Bethesda North Marriott Hotel & Conference Center, 5701...

  19. 78 FR 15728 - National Institute of Mental Health; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-12

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Mental Health; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Institute of Mental Health Special Emphasis Panel, March 28, 2013 from 01:00 p.m. to--04:30 p.m., National...

  20. 77 FR 72362 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-05

    ... Committee: Center for Scientific Review Special Emphasis Panel Member Conflict: AIDS Clinical Studies and Epidemiology Study Section. Date: December 13, 2012. Time: 11:00 a.m. to 1:00 p.m. Agenda: To review and....306, Comparative Medicine; 93.333, Clinical Research, 93.306, 93.333, 93.337, 93.393-93.396, 93.837-93...

  1. Evaluation of Sandwich Structure Bonding In Out-of-Autoclave Processing

    NASA Technical Reports Server (NTRS)

    Hou, Tan-Hung; Baughman, James M.; Zimmerman, Thomas J.; Sutter, James K.; Gardner, John M.

    2010-01-01

    The out-of-autoclave-vacuum-bag-only (OOA-VBO) process is low in capital expenditures compared to the traditional autoclave, however, the material challenges for OOA-VBO workable material systems are high. Presently there are few such aerospace grade prepreg materials available commercially. In this study, we evaluated processing and properties of honeycomb sandwich structure (HC/SS) panels fabricated by co-curing composite face sheet with adhesives by the OOA-VBO process in an oven. The prepreg materials were IM7/MTM 45-1 and T40-800B/5320. Adhesives studied were AF-555M, XMTA-241/PM15, FM-309-1M and FM-300K. Aluminum H/C cores with and without perforations were included. It was found that adhesives in IM7/MTM 45-1/AF-555M, T40-800B/5320/FM 309-1M and T40-800B/5320/FM-300K panels all foamed but yielded high flatwise tensile (FWT) strength values above 8,275 kPA (1,200 psi). IM7/MTM 45-1/XMTA-241/PM15 did not foam, yet yielded a low FWT strength. SEM photomicrographs revealed that the origin of this low strength was poor adhesion in the interfaces between the adhesive and face sheet composite due to poor wetting associated with the high initial viscosity of the XMTA-241/PM15 adhesive.

  2. 77 FR 61053 - Open Meeting of the Taxpayer Advocacy Panel Face-to-Face Service Methods Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-05

    ... Face-to-Face Service Methods Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Face-to-Face Service Methods... Service Methods Project Committee will be held Tuesday, November 13, 2012, at 2:00 p.m. Eastern Time via...

  3. 77 FR 47166 - Open Meeting of the Taxpayer Advocacy Panel Face-to-Face Service Methods Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-07

    ... Face-to-Face Service Methods Project Committee AGENCY: Internal Revenue Service (IRS) Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Face-to-Face Service Methods... Service Methods Project Committee will be held Tuesday, September 11, 2012, at 2 p.m. Eastern Time via...

  4. 76 FR 78342 - Open Meeting of the Taxpayer Advocacy Panel Face-to-Face Service Methods Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-16

    ... Face-to-Face Service Methods Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of Meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Face-to-Face Service Methods... Service Methods Project Committee will be held Tuesday, January 10, 2012, at 2 p.m. Eastern Time via...

  5. 76 FR 27070 - National Institute of Allergy and Infectious Diseases;

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-10

    ... Allergy and Infectious Diseases; Notice of Closed Meetings Pursuant to section 10(d) of the Federal... Infectious Diseases Special Emphasis Panel, NIAID Peer Review Meeting 1. Date: June 1, 2011. Time: 8 a.m. to... Diseases Special Emphasis Panel, NIAID Peer Review Meeting 3. Date: June 2, 2011. Time: 8 a.m. to 1:30 p.m...

  6. 77 FR 70791 - National Institute of Neurological Disorders and Stroke; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-27

    ... Neurological Disorders and Stroke; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory... Disorders and Stroke Special Emphasis Panel; Translational SEP. Date: November 30, 2012. Time: 2:00 p.m. to... Institute of Neurological Disorders and Stroke Special Emphasis Panel; NINDS T-32. Date: December 12, 2012...

  7. 75 FR 19983 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-16

    ... Cardiovascular Conditions (GenTAC). Date: May 12, 2010. Time: 10 a.m. to 1 p.m. Agenda: To review and evaluate... Emphasis Panel, NHLBI Cardiovascular Outcomes Research Coordinating Unit. Date: May 25, 2010. Time: 8 a.m... Blood Institute Special Emphasis Panel, NHLBI Centers for Cardiovascular Outcomes Research. Date: May 25...

  8. 78 FR 6122 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-29

    ... Digestive and Kidney Diseases Special Emphasis Panel, Stone Repeat. Date: February 25, 2013. Time: 6:00 p.m... Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings Pursuant to section 10(d) of the... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel, Renal Transport Program Projects. Date...

  9. 78 FR 26792 - National Institute of Allergy and Infectious Diseases; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-08

    ... Institute of Allergy and Infectious Diseases Special Emphasis Panel; Clinical Trials Units for NIAID... Infectious Diseases Special Emphasis Panel; Clinical Trials Units for NIAID Networks. Date: June 5, 2013...; Clinical Trails Unit for NIAID Networks. Date: June 6, 2013. Time: 9:30 a.m. to 6:30 p.m. Agenda: To review...

  10. 76 FR 23325 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-26

    ... Panel; Fellowships in Digestive Diseases and Nutrition Date: June 22, 2011. Time: 8:30 a.m. to 5 p.m... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel; DEM Fellowships. Date: June 15-16, 2011..., Diabetes, Endocrinology and Metabolic Research; 93.848, Digestive Diseases and Nutrition [[Page 23326...

  11. 78 FR 35637 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-13

    ... Institute Special Emphasis Panel; Functional Assays to Screen Genomic Hits. Date: July 2, 2013. Time: 8:30 a... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Heart, Lung, and... Panel; Clinical Trials SEP Review. Date: July 3, 2013. Time: 11:00 a.m. to 1:00 p.m. Agenda: To review...

  12. 77 FR 2611 - Open Meeting of the Taxpayer Advocacy Panel Face-to-Face Service Methods Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-18

    ... Face-to-Face Service Methods Project Committee AGENCY: Internal Revenue Service (IRS) Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Face-to-Face Service Methods... Service Methods Project Committee will be held Tuesday, February 14, 2012, at 2 p.m. Eastern Time via...

  13. 77 FR 30592 - Open Meeting of the Taxpayer Advocacy Panel Bankruptcy Compliance Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-23

    ... Bankruptcy Compliance Project Committee will be held Thursday, June 28th at 8:00 a.m. to 4:30 p.m. and Friday... Bankruptcy Compliance Project Committee AGENCY: Internal Revenue Service (IRS) Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Bankruptcy Compliance Project Committee...

  14. 75 FR 55406 - Open Meeting of the Taxpayer Advocacy Panel Earned Income Tax Credit Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-10

    ... Earned Income Tax Credit Project Committee AGENCY: Internal Revenue Service (IRS) Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Earned Income Tax Credit... Income Tax Credit Project Committee will be held Wednesday, October 27, 2010, at 1:00 p.m. Eastern Time...

  15. 75 FR 62632 - Open Meeting of the Taxpayer Advocacy Panel Earned Income Tax Credit Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-12

    ... Earned Income Tax Credit Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Earned Income Tax Credit... Income Tax Credit Project Committee will be held Wednesday, November 24, 2010, at 1 p.m. Eastern Time via...

  16. 76 FR 56879 - Open Meeting of the Taxpayer Advocacy Panel Earned Income Tax Credit Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-14

    ... Earned Income Tax Credit Project Committee AGENCY: Internal Revenue Service (IRS) Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Earned Income Tax Credit... Earned Income Tax Credit Project Committee will be held Monday, October 24, 2011, at 3 p.m. Eastern Time...

  17. 76 FR 63716 - Open Meeting of the Taxpayer Advocacy Panel Earned Income Tax Credit Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-13

    ... Earned Income Tax Credit Project Committee AGENCY: Internal Revenue Service (IRS) Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Earned Income Tax Credit... Earned Income Tax Credit Project Committee will be held Monday, November 28, 2011, at 3 p.m. Eastern Time...

  18. 76 FR 37199 - Open Meeting of the Taxpayer Advocacy Panel Earned Income Tax Credit Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-24

    ... Earned Income Tax Credit Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Earned Income Tax Credit... Income Tax Credit Project Committee will be held Monday, August 22, 2011, at 3 p.m. Eastern Time via...

  19. 75 FR 39333 - Open Meeting of the Taxpayer Advocacy Panel Earned Income Tax Credit Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-08

    ... Earned Income Tax Credit Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Earned Income Tax Credit... Income Tax Credit Project Committee will be held Wednesday, August 25, 2010, at 1 p.m. Eastern Time via...

  20. China's Air Quality and Respiratory Disease Mortality Based on the Spatial Panel Model.

    PubMed

    Cao, Qilong; Liang, Ying; Niu, Xueting

    2017-09-18

    Background : Air pollution has become an important factor restricting China's economic development and has subsequently brought a series of social problems, including the impact of air pollution on the health of residents, which is a topical issue in China. Methods : Taking into account this spatial imbalance, the paper is based on the spatial panel data model PM 2.5 . Respiratory disease mortality in 31 Chinese provinces from 2004 to 2008 is taken as the main variable to study the spatial effect and impact of air quality and respiratory disease mortality on a large scale. Results : It was found that there is a spatial correlation between the mortality of respiratory diseases in Chinese provinces. The spatial correlation can be explained by the spatial effect of PM 2.5 pollutions in the control of other variables. Conclusions : Compared with the traditional non-spatial model, the spatial model is better for describing the spatial relationship between variables, ensuring the conclusions are scientific and can measure the spatial effect between variables.

  1. 77 FR 16246 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-20

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on... and Alcoholism Special Emphasis Panel; Longitudinal Studies on the Impact of Adolescent Drinking on the Adolescent Brain. Date: April 16-17, 2012 Time: 8 a.m. to 8 p.m. Agenda: To review and evaluate...

  2. 75 FR 35076 - National Institute of Environmental Health Sciences; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-21

    ... Branch, Division of Extramural Research and Training, Nat. Institute of Environmental Health Science, P.O... Environmental Health Sciences; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory... Health Sciences Special Emphasis Panel, Pediatric Lung Function Study. Date: July 1, 2010. Time: 1 p.m...

  3. 75 FR 19408 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-14

    [email protected] . Name of Committee: Healthcare Delivery and Methodologies, Community-Level Health... Panel, Member Conflict: Cell Biology. Date: May 19-20, 2010. Time: 8 a.m. to 5 p.m. Agenda: To review... Clinical Integrated Review Group, Radiation Therapeutics and Biology Study Section. Date: May 24-25, 2010...

  4. 78 FR 46358 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-31

    ... Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings Pursuant to section 10(d) of the... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel, NIDDK Central Repositories Non-Renewable Sample Access (X01): Kidney, Urology and Hepatitis C. Date: August 16, 2013. Time: 1:00 p.m. to 4:00 p.m...

  5. 75 FR 31798 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-04

    ... public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C..., Member Conflicts: Cognition and Perception. Date: June 25, 2010. Time: 1 p.m. to 3 p.m. Agenda: To review...: Center for Scientific Review Special Emphasis Panel, ARRA: Risk Prevention and Health Behavior Across the...

  6. 75 FR 28029 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-19

    ... Institute of Diabetes and Digestive and Kidney Diseases Special Emphasis Panel; Obesity, Hypertension and Diabetes. Date: July 6, 2010. Time: 1 p.m. to 2:30 p.m. Agenda: To review and evaluate grant applications... Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings Pursuant to section 10(d) of the...

  7. 76 FR 76168 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-06

    ... Nutrition. Date: February 21, 2012. Time: 8 a.m. to 5 p.m. Agenda: To review and evaluate grant applications... Emphasis Panel, Translational Research. Date: January 26, 2012. Time: 8 a.m. to 5 p.m. [[Page 76169... Nos. 93.847, Diabetes, Endocrinology and Metabolic Research; 93.848, Digestive Diseases and Nutrition...

  8. 75 FR 78717 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-16

    ... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel; Central Repositories Non-Renewable Sample Access (PAR-10-90)-Type 1 Diabetes. Date: January 24, 2011. Time: 2 p.m. to 4 p.m. Agenda: To... Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings Pursuant to section 10(d) of the...

  9. 78 FR 34111 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-06

    ... Designs on Diabetes Complications. Date: July 1, 2013. Time: 1:00 p.m. to 2:00 p.m. Agenda: To review and... Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings Pursuant to section 10(d) of the... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel; PAR-11-043 Calcium Metabolism Program...

  10. 75 FR 19980 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-16

    ... Institute of Child Health and Human Development Special Emphasis Panel; Gene Therapy for Urea Cycle Disorders. Date: April 30, 2010. Time: 1:30 p.m. to 3 p.m. Agenda: To review and evaluate grant applications... prior to the meeting due to the timing limitations imposed by the review and funding cycle. (Catalogue...

  11. 78 FR 19499 - National Institute on Drug Abuse; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-01

    ... personal privacy. Name of Committee: National Institute on Drug Abuse Special Emphasis Panel PAR-12-297: Mechanism for Time-Sensitive Drug Abuse Research. Date: April 9, 2013. Time: 12:00 p.m. to 2:00 p.m. Agenda... Institute on Drug Abuse, NIH, DHHS, 6001 Executive Blvd., Room 4226, MSC 9550, Bethesda, MD 20892-9550, 301...

  12. 78 FR 66946 - National Cancer Institute; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-07

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Cancer Institute Special Emphasis Panel, December 04, 2013, 01:00 p.m. to December 04, 2013, 02:30 p.m., NCI Shady Grove, 9609 Medical Center Drive, Room 7W11...

  13. 76 FR 21749 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-18

    ... meeting: Time and Date: 12 p.m.-4 p.m., June 21, 2011 (Closed). Place: Teleconference. Status: The meeting will be closed to the public in accordance with provisions set forth in Section 552b(c)(4) and (6...., M.P.H., Scientific Review Officer, Center of Global Health Science Office, Center for Global Health...

  14. 76 FR 9578 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Conducting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-18

    ... aforementioned meeting: Time and Date: 12:30 p.m.-3 p.m., April 13, 2011 (Closed). Place: Teleconference. Status: The meeting will be closed to the public in accordance with provisions set forth in Section 552b(c) (4..., initial review.'' Contact Person for More Information: Diana Bartlett, M.P.H., Scientific Review Officer...

  15. 78 FR 52535 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-23

    ...(c) (4) and (6), Title 5 U.S.C., and the Determination of the Director, Management Analysis and....S., M.P.H., Scientific Review Officer, CDC, 1600 Clifton Road NE., Mailstop E60, Atlanta, Georgia... aforementioned meeting: Time and Date: 1:00 p.m.-3:00 p.m., October 17, 2013 (Closed). Place: Teleconference...

  16. 76 FR 21748 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-18

    ... meeting: Time and Date: 12 p.m.-4 p.m., June 23, 2011 (Closed). Place: Teleconference. Status: The meeting will be closed to the public in accordance with provisions set forth in Section 552b(c)(4) and (6...., M.P.H., Scientific Review Officer, Center of Global Health Science Office, Center for Global Health...

  17. CONTRIBUTION OF FINE PARTICLES OF OUTDOOR ORIGIN TO PERSONAL EXPOSURES: RESULTS OF A 37-PERSON PANEL STUDY IN NORTH CAROLINA

    EPA Science Inventory

    The US EPA carried out a study of personal exposures to PM2.5 for 37 persons with hypertension or cardiovascular disease in North Carolina. Personal, indoor (home) and outdoor (home and central site) 24-h samples were collected for 7 consecutive days in each of four seasons in...

  18. [The impact of ambient fine particulate matter on the blood pressure of an urban population in Shanghai, China: a panel study].

    PubMed

    Xu, W X; Chen, R J; Kan, H D

    2016-08-06

    To investigate the impact of particulate matter 2.5 (PM2.5) on the blood pressure of urban residents in Shanghai, China. A panel study was conducted from May 27(th) to June 5(th) 2014 in a cohort of 30 adults in an urban community. Participants were 50-80 years old, had lived in the community for at least 5 years, and had a good health status. Key exclusion criteria were current smoking, smoking during the last 3 years, passive smoking, alcohol consumption, and severe cardiopulmonary disease. A total of 28 participants were eligible. Information on demographic characteristics, including of age, sex, height, weight, education, income and chronic comorbidities were collected. Participants were requested to have six weekly blood pressure measurements. Real-time concentrations of PM2.5 and gaseous pollutants were obtained from a nearby air quality monitor during 40 d. Pearson correlation was applied to analyze the correlation between PM2.5 and SO2, NO2, CO and O3. Linear mixed models were applied to analyze the association between PM2.5 and blood pressure, after controlling for time-related trends, day of the week, mean temperature, relative humidity and individual characteristics. The mean systolic and diastolic blood pressure was (124.0±15.0) mmHg (1 mmHg=0.133 kPa) and (74.0±7.7) mmHg, respectively. At 24 h before blood pressure measurement, the mean PM2.5, SO2, NO2, O3 and CO concentration were (8.3±4.9), (46.6±12.9) , (79.2±27.4) μg/m(3) and (0.8±0.2) mg/m(3). The Pearson correlation coefficient R, between PM2.5 and O3, SO2, NO2 and CO was 0.79, 0.59, 0.34 and 0.45, respectively, with corresponding P-values of <0.001, 0.006, 0.012 and 0.009, respectively. The significant correlation between PM2.5 and systolic blood pressure occurred at lag 1 day, was strongest at lag 3 day, but attenuated thereafter. A 10 μg/m(3) increase in 3-day average concentrations of PM2.5 was associated with changes of 1.86 (95%CI: 0.62-3.09) mmHg in systolic blood pressure and -0.05 (95%CI: 0.59-0.50) mmHg in diastolic blood pressure. Short-term exposure to PM2.5 may significantly elevate the systolic blood pressure of urban residents in Shanghai.

  19. 75 FR 36065 - Meeting of the Ocean Research and Resources Advisory Panel

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-24

    ... and Resources Advisory Panel (ORRAP) will hold a regularly scheduled meeting. The meeting will be open to the public. DATES: The meeting will be held on Tuesday, July 27, 2010, from 8:30 a.m. to 5:30 p.m... comments in advance of the meeting to the meeting Point of Contact. ADDRESSES: The meeting will be held at...

  20. 76 FR 16391 - Meeting of the Ocean Research and Resources Advisory Panel

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-23

    ... and Resources Advisory Panel (ORRAP) will hold a meeting. The meeting will be open to the public. DATES: The meeting will be held on Monday, April 25, 2011, from 8:30 a.m. to 5:30 p.m. and Tuesday... of the meeting to the meeting Point of Contact. ADDRESSES: The meeting will be held at the Consortium...

  1. 77 FR 37421 - National Institute of Neurological Disorders and Stroke; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-21

    ... Neurological Disorders and Stroke; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory... Disorders and Stroke Special Emphasis Panel, NINDS Center for Clinical Trial Resources. Date: July 10, 2012... Stroke Special Emphasis Panel, PD Biomarker Review. Date: July 18, 2012. Time: 8:00 a.m. to 6:00 p.m...

  2. 77 FR 58982 - Fisheries of the South Atlantic; South Atlantic Fishery Management Council; Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-25

    ... joint meeting of its Deepwater Shrimp Advisory Panel (AP) and Coral Advisory Panel in Cape Canaveral, FL. DATES: Members of the Deepwater Shrimp AP and Coral AP will meet jointly from 8:30 a.m. until 5 p.m. on... at the meeting include: An overview of the rock shrimp fishery and of deepwater coral resources...

  3. 78 FR 30930 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-23

    ... Panel; Small Business: Radiation Therapy and Biology. Date: June 18-19, 2013. Time: 9:00 a.m. to 8:00 p...: Accelerating the Pace of Drug Abuse Research Using Existing Data. Date: June 20, 2013. Time: 1:00 p.m. to 4:00...: Center for Scientific Review Special Emphasis Panel; PA-12-139: Pilot and Feasibility Clinical Research...

  4. 78 FR 34111 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-06

    ... Emphasis Panel; Diabetes and Alzheimer's Disease. Date: July 19, 2013. Time: 1:00 p.m. to 4:00 p.m. Agenda... U.S.C. App.), notice is hereby given of the following meetings. The meetings will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C...

  5. 75 FR 2876 - National Institute of Environmental Health Sciences; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-19

    ... Emphasis Panel; SBIR Phase 1 Transgenic C Elegans. Date: February 11, 2010. Time: 1 p.m. to 3 p.m. Agenda... Committee Act, as amended (5 U.S.C. App.), notice is hereby given of the following meetings. The meetings will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and...

  6. 78 FR 9055 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-07

    ...: Time and Date: 1:00 p.m.-3:00 p.m., March 28, 2013 (Closed). Place: Teleconference. Status: The meeting will be closed to the public in accordance with provisions set forth in Section 552b(c) (4) and (6...-002''. Contact Person for More Information: Gregory Anderson, M.S., M.P.H., Scientific Review Officer...

  7. 75 FR 13559 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Long Term...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-22

    ... Date: 12 p.m.-2 p.m., June 8, 2010 (Closed). Place: Teleconference. Status: The meeting will be closed to the public in accordance with provisions set forth in Section 552b(c) (4) and (6), Title 5 U.S.C... CMV Infection, FOA IP10-006.'' For More Information Contact: Gregory Anderson, M.S., M.P.H...

  8. 78 FR 37837 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-24

    ...: Basic Research on Human Embryonic Stem Cells. Date: July 16-17, 2013. Time: 8:00 a.m. to 5:00 p.m... Panel; RFA-RM-13-002: Planning Grants for the NIH National Research Mentoring Network (NRMN) P20. Date... and Related Research Integrated Review Group; NeuroAIDS and other End-Organ Diseases Study Section...

  9. 77 FR 43343 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-24

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Heart, Lung, and... unwarranted invasion of personal privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel; Jackson Heart Study RFA Review. Date: August 15, 2012. Time: 8:00 a.m. to 5:30 p.m. Agenda...

  10. EXHALED NITRIC OXIDE IS ASSOCIATED WITH OUTDOOR, INDOOR, AND PERSONAL PM2.5 IN CHILDREN WITH ASTHMA IN A PANEL STUDY. (R827355C002)

    EPA Science Inventory

    The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Concl...

  11. 78 FR 29757 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-21

    ... Review Group; Bacterial Pathogenesis Study Section. Date: June 11, 2013. Time: 8:00 a.m. to 6:00 p.m... Special Emphasis Panel; PAR-13-009: Secondary Dataset Analyses in Heart, Lung, and Blood Diseasesand Sleep... Analyses in Heart, Lung, and Blood Diseases and Sleep Disorders: Conflicts. Date: June 17, 2013 Time: 8:30...

  12. Traffic-related air pollution exposures and changes in heart rate variability in Mexico City: a panel study.

    PubMed

    Shields, Kyra Naumoff; Cavallari, Jennifer M; Hunt, Megan J Olson; Lazo, Mariana; Molina, Mario; Molina, Luisa; Holguin, Fernando

    2013-01-18

    While air pollution exposures have been linked to cardiovascular outcomes, the contribution from acute gas and particle traffic-related pollutants remains unclear. Using a panel study design with repeated measures, we examined associations between personal exposures to traffic-related air pollutants in Mexico City and changes in heart rate variability (HRV) in a population of researchers aged 22 to 56 years. Participants were monitored for approximately 9.5 hours for eight days while operating a mobile laboratory van designed to characterize traffic pollutants while driving in traffic and "chasing" diesel buses. We examined the association between HRV parameters (standard deviation of normal-to-normal intervals (SDNN), power in high frequency (HF) and low frequency (LF), and the LF/HF ratio) and the 5-minute maximum (or average in the case of PM(2.5)) and 30-, 60-, and 90-minute moving averages of air pollutants (PM(2.5), O(3), CO, CO(2), NO(2), NO(x), and formaldehyde) using single- and two-pollutant linear mixed-effects models. Short-term exposure to traffic-related emissions was associated with statistically significant acute changes in HRV. Gaseous pollutants - particularly ozone - were associated with reductions in time and frequency domain components (α = 0.05), while significant positive associations were observed between PM(2.5) and SDNN, HF, and LF. For ozone and formaldehyde, negative associations typically increased in magnitude and significance with increasing averaging periods. The associations for CO, CO(2), NO(2), and NO(x) were similar with statistically significant associations observed for SDNN, but not HF or LF. In contrast, PM(2.5) increased these HRV parameters. Results revealed an association between traffic-related PM exposures and acute changes in HRV in a middle-aged population when PM exposures were relatively low (14 μg/m(3)) and demonstrate heterogeneity in the effects of different pollutants, with declines in HRV - especially HF - with ozone and formaldehyde exposures, and increases in HRV with PM(2.5) exposure. Given that exposure to traffic-related emissions is associated with increased risk of cardiovascular morbidity and mortality, understanding the mechanisms by which traffic-related emissions can cause cardiovascular disease has significant public health relevance.

  13. 77 FR 30591 - Open Meeting of the Taxpayer Advocacy Panel Face-to-Face Service Methods Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-23

    ... Face-to-Face Service Methods Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Face-to-Face [[Page 30592... meeting will be held Thursday, June 7 from 8:00 a.m.-5:00 p.m. Eastern Time and Friday, June 8 from 8:00 a...

  14. 78 FR 64226 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-28

    ... public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C... personal privacy. Name of Committee: Center for Scientific Review Special Emphasis Panel; SBIR/STTR HDM... Emphasis Panel; SBIR/STTR HDM Informatics. Date: October 30, 2013. Time: 9:00 a.m. to 6:00 p.m. Agenda: To...

  15. 77 FR 2096 - Proposal Review Panel for Materials Research; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-13

    ... Engineering Center (MRSEC) at Massachusetts Institute of Technology (MIT) by the Division of Materials... 16, 2012 7:15 a.m.-8:15 a.m. Closed--Executive Session 8:15 a.m.-5 p.m. Open--Review of the MIT MRSEC... session 9 a.m.-10 a.m. Open--Review of the MIT MRSEC 10 a.m.-4:30 p.m. Closed--Executive Session, Report...

  16. 77 FR 52750 - National Library of Medicine; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-30

    ... U.S.C. App), notice is hereby given of the following meeting. The meeting will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 USC, as... Special Emphasis Panel; R01/R21/G13. Date: October 26, 2012. Time: 12 p.m. to 4 p.m. Agenda: To review and...

  17. PM2.5 mitigation in China: Socioeconomic determinants of concentrations and differential control policies.

    PubMed

    Luo, Kui; Li, Guangdong; Fang, Chuanglin; Sun, Siao

    2018-05-01

    Elucidating the key impact factors on PM 2.5 concentrations is crucial to formulate effective mitigation policies. In this study, we employed an extended Stochastic Impacts by Regression on Population Affluence and Technology (STIRPAT) model to identify the socioeconomic determinants of PM 2.5 concentrations for 12 different regions and across China. The evaluation was based on a balanced panel dataset integrating long-term satellite-derived PM 2.5 concentrations and socio-economic data in China from 1999 to 2011. Empirical results indicate that the influencing factors can be ranked in descending order of importance as: proportion of secondary sector of the economy, GDP per capita, urbanization, population, energy intensity, and proportion of tertiary sector. Proportion of secondary sector is the greatest contribution to increasing PM 2.5 concentrations, especially for heavily polluted regions. GDP per capita is secondary in importance, and its impact is weakened by the existence of an EKC relationship between GDP per capita and PM 2.5 concentrations. Therefore, PM 2.5 pollution is an economic development mode problem, rather than a general economic development problem. The impact of urbanization varies across regions; while promoting urbanization will be conducive to decreased PM 2.5 concentrations in Northwest China and Northeast China, it will contribute to increased PM 2.5 concentrations in other regions. Population and energy intensity are significant in most regions, but neither are decisive factors because of the small absolute value of their coefficients. Finally, different combinations of mitigation policies are proposed for different regions in this study to meet the mitigation targets. Copyright © 2018 Elsevier Ltd. All rights reserved.

  18. 77 FR 64816 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-23

    ... Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings Pursuant to section 10(d) of the... Institute of Diabetes and Digestive and Kidney Diseases Special Emphasis Panel; Ancillary Studies on Molecular Genetics of Kidney and Urinary Tract Diseases. Date: December 10, 2012. Time: 1:00 p.m. to 2:00 p...

  19. 77 FR 7167 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-10

    ... Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings Pursuant to section 10(d) of the... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel Multi-Center Study of Tamsulosin for Ureteral Stones in the Emergency Department. Date: March 26, 2012. Time: 11 a.m. to 12 p.m. Agenda: To...

  20. 77 FR 66076 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-01

    ... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel; PAR-11-350 Research Using Biosamples from Selected Type 1 Diabetes Clinical Studies (DP3). Date: December 4, 2012. Time: 1:30 p.m. to 5:00 p... Diabetes and Digestive and Kidney Diseases; Notice of Closed Meeting Pursuant to section 10(d) of the...

  1. China’s Air Quality and Respiratory Disease Mortality Based on the Spatial Panel Model

    PubMed Central

    Cao, Qilong; Liang, Ying; Niu, Xueting

    2017-01-01

    Background: Air pollution has become an important factor restricting China’s economic development and has subsequently brought a series of social problems, including the impact of air pollution on the health of residents, which is a topical issue in China. Methods: Taking into account this spatial imbalance, the paper is based on the spatial panel data model PM2.5. Respiratory disease mortality in 31 Chinese provinces from 2004 to 2008 is taken as the main variable to study the spatial effect and impact of air quality and respiratory disease mortality on a large scale. Results: It was found that there is a spatial correlation between the mortality of respiratory diseases in Chinese provinces. The spatial correlation can be explained by the spatial effect of PM2.5 pollutions in the control of other variables. Conclusions: Compared with the traditional non-spatial model, the spatial model is better for describing the spatial relationship between variables, ensuring the conclusions are scientific and can measure the spatial effect between variables. PMID:28927016

  2. 78 FR 26399 - Arts Advisory Panel Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-06

    ... times are approximate): Arts Education (application review): By teleconference. This meeting will be closed. Dates: May 22, 2013; 11:00 a.m. to 12:00 p.m. Innovation (application review): By teleconference...

  3. Cultivar-Based Introgression Mapping Reveals Wild Species-Derived Pm-0, the Major Powdery Mildew Resistance Locus in Squash.

    PubMed

    Holdsworth, William L; LaPlant, Kyle E; Bell, Duane C; Jahn, Molly M; Mazourek, Michael

    2016-01-01

    Powdery mildew is a major fungal disease on squash and pumpkin (Cucurbita spp.) in the US and throughout the world. Genetic resistance to the disease is not known to occur naturally within Cucurbita pepo and only infrequently in Cucurbita moschata, but has been achieved in both species through the introgression of a major resistance gene from the wild species Cucurbita okeechobeensis subsp. martinezii. At present, this gene, Pm-0, is used extensively in breeding, and is found in nearly all powdery mildew-resistant C. pepo and C. moschata commercial cultivars. In this study, we mapped C. okeechobeensis subsp. martinezii-derived single nucleotide polymorphism (SNP) alleles in a set of taxonomically and morphologically diverse and resistant C. pepo and C. moschata cultivars bred at Cornell University that, by common possession of Pm-0, form a shared-trait introgression panel. High marker density was achieved using genotyping-by-sequencing, which yielded over 50,000 de novo SNP markers in each of the three Cucurbita species genotyped. A single 516.4 kb wild-derived introgression was present in all of the resistant cultivars and absent in a diverse set of heirlooms that predated the Pm-0 introgression. The contribution of this interval to powdery mildew resistance was confirmed by association mapping in a C. pepo cultivar panel that included the Cornell lines, heirlooms, and 68 additional C. pepo cultivars and with an independent F2 population derived from C. okeechobeensis subsp. martinezii x C. moschata. The interval was refined to a final candidate interval of 76.4 kb and CAPS markers were developed inside this interval to facilitate marker-assisted selection.

  4. Cultivar-Based Introgression Mapping Reveals Wild Species-Derived Pm-0, the Major Powdery Mildew Resistance Locus in Squash

    PubMed Central

    Holdsworth, William L.; LaPlant, Kyle E.; Bell, Duane C.; Jahn, Molly M.; Mazourek, Michael

    2016-01-01

    Powdery mildew is a major fungal disease on squash and pumpkin (Cucurbita spp.) in the US and throughout the world. Genetic resistance to the disease is not known to occur naturally within Cucurbita pepo and only infrequently in Cucurbita moschata, but has been achieved in both species through the introgression of a major resistance gene from the wild species Cucurbita okeechobeensis subsp. martinezii. At present, this gene, Pm-0, is used extensively in breeding, and is found in nearly all powdery mildew-resistant C. pepo and C. moschata commercial cultivars. In this study, we mapped C. okeechobeensis subsp. martinezii-derived single nucleotide polymorphism (SNP) alleles in a set of taxonomically and morphologically diverse and resistant C. pepo and C. moschata cultivars bred at Cornell University that, by common possession of Pm-0, form a shared-trait introgression panel. High marker density was achieved using genotyping-by-sequencing, which yielded over 50,000 de novo SNP markers in each of the three Cucurbita species genotyped. A single 516.4 kb wild-derived introgression was present in all of the resistant cultivars and absent in a diverse set of heirlooms that predated the Pm-0 introgression. The contribution of this interval to powdery mildew resistance was confirmed by association mapping in a C. pepo cultivar panel that included the Cornell lines, heirlooms, and 68 additional C. pepo cultivars and with an independent F2 population derived from C. okeechobeensis subsp. martinezii x C. moschata. The interval was refined to a final candidate interval of 76.4 kb and CAPS markers were developed inside this interval to facilitate marker-assisted selection. PMID:27936008

  5. 78 FR 76660 - Arts Advisory Panel Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-18

    ... p.m. in room 716. Music (review of nominations): This meeting will be closed. Dates: January 14... Columbus Circle, 12th Floor, New York, NY 10019. Music (application review): This meeting will be virtual...

  6. An evaluation of indoor and outdoor biological particulate matter

    NASA Astrophysics Data System (ADS)

    Menetrez, M. Y.; Foarde, K. K.; Esch, R. K.; Schwartz, T. D.; Dean, T. R.; Hays, M. D.; Cho, S. H.; Betancourt, D. A.; Moore, S. A.

    The incidences of allergies, allergic diseases and asthma are increasing world wide. Global climate change is likely to impact plants and animals, as well as microorganisms. The World Health Organization, U.S. Environmental Protection Agency, U.S. Department of Agriculture, U.S. Department of Health and Human Services, and the Intergovernmental Panel on Climate Change cite increased allergic reactions due to climate change as a growing concern. Monitoring of indoor and ambient particulate matter (PM) and the characterization of the content for biological aerosol concentrations has not been extensively performed. Samples from urban and rural North Carolina (NC), and Denver (CO), were collected and analyzed as the goal of this research. A study of PM 10 (<10 μm in aerodynamic diameter) and PM 2.5 (<2.5 μm in aerodynamic diameter) fractions of ambient bioaerosols was undertaken for a six month period to evaluate the potential for long-term concentrations. These airborne bioaerosols can induce irritational, allergic, infectious, and chemical responses in exposed individuals. Three separate sites were monitored, samples were collected and analyzed for mass and biological content (endotoxins, (1,3)-β- D-glucan and protein). Concentrations of these bioaerosols were reported as a function of PM size fraction, mass and volume of air sampled. The results indicated that higher concentrations of biologicals were present in PM 10 than were present in PM 2.5, except when near-roadway conditions existed. This study provides the characterization of ambient bioaerosol concentrations in a variety of areas and conditions.

  7. 13. Historic American Buildings Survey John O. Brostrup, Photographer May ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. Historic American Buildings Survey John O. Brostrup, Photographer May 6, 1937 2:30 P.M. DETAIL OF PANELED DOOR. - Holly Hill, Southeast of Friendship off MD 631, Friendship, Anne Arundel County, MD

  8. 76 FR 58523 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-21

    ...: Center for Scientific Review Special Emphasis Panel, Fellowships: Sensory, Motor, and Cognitive Neuroscience. Date: October 20-21, 2011. Time: 8 a.m. to 5 p.m. Agenda: To review and evaluate grant...

  9. 76 FR 14675 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-17

    ... Panel; Member Conflict: Molecular AIDS and Related Research Topics. Date: April 4, 2011. Time: 2 p.m. to... . (Catalogue of Federal Domestic Assistance Program Nos. 93.306, Comparative Medicine; 93.333, Clinical...

  10. 77 FR 32496 - Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-01

    ... a.m. Time: 9 a.m. to 12 p.m. Location: Georgetown University, Healy Hall Lawn (site of ACVFA meeting... opening remarks, followed by panel discussions among ACVFA members and USAID leadership, and open Q&A. A...

  11. 78 FR 24428 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-25

    ... Emphasis Panel; Member Conflict: Neural Engineering and Neurogenetics. Date: May 22, 2013. Time: 2:00 p.m... Federal Domestic Assistance Program Nos. 93.306, Comparative Medicine; 93.333, Clinical Research, 93.306...

  12. 77 FR 13135 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-05

    ... Special Emphasis Panel; Member Conflict: Host defense, lung injury and lung molecular biology and...; Member Conflict: Cancer Biology, Genetics and Carcinogenesis. Date: March 27-28, 2012. Time: 1 p.m. to 5...

  13. 78 FR 65344 - Center for Scientific Review; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-31

    ... Review Special Emphasis Panel, Small Business: Psycho/ Neuropathology, Lifespan Development, and Science Education, October 24, 2013, 08:00 a.m. to October 25, 2013, 06:00 p.m., Renaissance Seattle Hotel, 515...

  14. 75 FR 29769 - National Cancer Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-27

    ... Cancer Institute Special Emphasis Panel; Integrating Patient-Reported Outcomes in Hospice and Palliative Care Practices. Date: June 1, 2010. Time: 11 a.m. to 2 p.m. Agenda: To review and evaluate contract...

  15. 75 FR 48978 - National Institute of Allergy and Infectious Diseases; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-12

    ... Infectious Diseases Special Emphasis Panel; T-Cell Immunology. Date: September 16, 2010. Time: 12:30 p.m. to....gov . (Catalogue of Federal Domestic Assistance Program Nos. 93.855, Allergy, Immunology, and...

  16. 78 FR 26054 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-03

    ... Validation of Novel Targets for Alzheimer's Disease. Date: June 25, 2013. Time: 11:30 a.m. to 5:30 p.m... Committee: National Institute on Aging Special Emphasis Panel; Drug Development for Alzheimer's Disease...

  17. 78 FR 63999 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-25

    ... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Alzheimer's Disease Sequencing Project. Date: October 29, 2013. Time: 8:00 a.m. to 6:00 p.m. Agenda: To review and...

  18. 14. Historic American Buildings Survey John O. Brostrup, Photographer May ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Historic American Buildings Survey John O. Brostrup, Photographer May 6, 1937 2:45 P.M. DETAIL OF GRAINING ON PANELED DOOR. - Holly Hill, Southeast of Friendship off MD 631, Friendship, Anne Arundel County, MD

  19. 76 FR 78284 - Center For Scientific Review; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-16

    ... Panel, Member Conflict: Bioengineering Models and Technologies. Date: January 5, 2012. Time: 3 p.m. to 5... Domestic Assistance Program Nos. 93.306, Comparative Medicine; 93.333, Clinical Research, 93.306, 93.333...

  20. 75 FR 8374 - National Human Genome Research Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-24

    ... Emphasis Panel, Revolutionary Sequencing Technology. Date: April 2, 2010. Time: 8 a.m. to 5 p.m. Agenda: To review and evaluate grant applications. Place: Crystal City Marriott at Regan National Airport, 1999...

  1. 78 FR 6125 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-29

    [email protected] . Name of Committee: Brain Disorders and Clinical Neuroscience Integrated Review Group... Special Emphasis Panel; Small Business: Informatics. Date: February 25, 2013. Time: 8:30 a.m. to 5:00 p.m...

  2. 76 FR 72209 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-22

    ... Emphasis Panel, Predoctoral Training in Cardiovascular Research. Date: December 15, 2011. Time: 1 p.m. to 2..., Heart and Vascular Diseases Research; 93.838, Lung Diseases Research; 93.839, Blood Diseases and...

  3. 77 FR 63845 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-17

    ... Scientific Review Special Emphasis Panel; Member Conflict: Multiple Sclerosis, Neuroimmunology and Brain... Treatments (CDT). Date: November 12-13, 2012. Time: 8:00 a.m. to 5:00 p.m. Agenda: To review and evaluate...

  4. 75 FR 79386 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Hormone Therapy and Cognitive Aging. Date: January 11, 2011. Time: 11 a.m. to 12 p.m. Agenda: To review and evaluate...

  5. 77 FR 69641 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-20

    ... Review Special Emphasis Panel; Member Conflict: Children. Date: December 11, 2012. Time: 2:00 p.m. to 3... Federal Domestic Assistance Program Nos. 93.306, Comparative Medicine; 93.333, Clinical Research, 93.306...

  6. 78 FR 108 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-02

    ... Review Special Emphasis Panel Member Conflict: Molecular Genetics and Imaging in Neuroscience. Date...: Molecular and Cellular Hematology. Date: January 22-23, 2013. Time: 10:00 a.m. to 7:00 p.m. Agenda: To...

  7. 78 FR 39299 - National Institute of Neurological Disorders and Stroke; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-01

    ... Disorders and Stroke Special, Emphasis Panel, International Traumatic Brain Injury Research Initiative. Date... Traumatic Encephalopathy and Delayed Effects of Traumatic Brain Injury. Date: July 19, 2013. Time: 1:30 p.m...

  8. 75 FR 33816 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-15

    ... Scientific Review Special Emphasis Panel; Small Business: Computational Biology, Image Processing, and Data Mining. Date: July 21, 2010. Time: 8 a.m. to 6 p.m. Agenda: To review and evaluate grant applications...

  9. 77 FR 10539 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-22

    ... personal privacy. Name of Committee: Center for Scientific Review Special Emphasis Panel; Drug Discovery and Mechanisms of Antimicrobial Resistance Overflow. Date: March 1-2, 2012. Time: 9 a.m. to 5 p.m...

  10. 75 FR 9907 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-04

    ... Special Emphasis Panel, Fellowships: Physiology and Pathobiology of Musculoskeletal, Oral, and Skin Systems (F10B). Date: March 31, 2010. Time: 8 a.m. to 5 p.m. Agenda: To review and evaluate grant...

  11. 11TH Annual Science and Engineering Technology Conference/DoD Tech Exposition

    DTIC Science & Technology

    2010-04-15

    to meet with a Navy and Air Force Representative in One-on-One sessions. You may sign up for your private, 15 minute One-on-One session onsite at...Wednesday, April 14, 2010 1:00PM until 5:00PM THANK YOU TO OUR SPEAKERS AND PANEL MEMBERS The Wounded Warrior Project (WWP) has received a...conference. All registered attendees will receive an email notification once the proceedings are available. SURVEY A survey will be e-mailed to you

  12. Blood Pressure Changes and Chemical Constituents of Particulate Air Pollution: Results from the Healthy Volunteer Natural Relocation (HVNR) Study

    PubMed Central

    Wu, Shaowei; Deng, Furong; Huang, Jing; Wang, Hongyi; Shima, Masayuki; Wang, Xin; Qin, Yu; Zheng, Chanjuan; Wei, Hongying; Hao, Yu; Lv, Haibo; Lu, Xiuling

    2012-01-01

    Background: Elevated blood pressure (BP) has been associated with particulate matter (PM) air pollution, but associations with PM chemical constituents are still uncertain. Objectives: We investigated associations of BP with various chemical constituents of fine PM (PM2.5) during 460 repeated visits among a panel of 39 university students. Methods: Resting BP was measured using standardized methods before and after the university students relocated from a suburban campus to an urban campus with different air pollution contents in Beijing, China. Air pollution data were obtained from central monitors close to student residences. We used mixed-effects models to estimate associations of various PM2.5 constituents with systolic BP (SBP), diastolic BP (DBP), and pulse pressure. Results: An interquartile range increase of 51.2 μg/m3 in PM2.5 was associated with a 1.08-mmHg (95% CI: 0.17, 1.99) increase in SBP and a 0.96-mmHg (95% CI: 0.31, 1.61) increase in DBP on the following day. A subset of PM2.5 constituents, including carbonaceous fractions (organic carbon and elemental carbon), ions (chloride and fluoride), and metals/metalloid elements (nickel, zinc, magnesium, lead, and arsenic), were found to have robust positive associations with different BP variables, though robust negative associations of manganese, chromium, and molybdenum with SBP or DBP also were observed. Conclusions: Our results support relationships between specific PM2.5 constituents and BP. These findings have potential implications for the development of pollution abatement strategies that maximize public health benefits. PMID:23086577

  13. 2006 National Small Business Conference - Meeting DOD/DHS Mission Needs in the 21st Century

    DTIC Science & Technology

    2006-05-10

    Untitled Document National Small Business Conference.html[7/7/2016 1:35:33 PM] National Small Business Conference "Meeting DoD/DHS Mission Needs in...Defense Systems (Will be available soon) Panel: Program Manager’s Perspective on Small Business Contributions to Major Programs • Mr. Michael Hoeffler...Vice President, Future Naval Capability, Raytheon Company Small Business Success Story Panel: • Mr. Jay Boyce, Foster-Miller, Inc. (Will be

  14. 75 FR 11187 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ... for Scientific Review Special Emphasis Panel; Epidemiology of Diseases of Aging. Date: March 31, 2010... Conflicts: Cell Biology. Date: April 13-14, 2010. Time: 8 a.m. to 5 p.m. Agenda: To review and evaluate...

  15. 78 FR 14091 - Sunshine Act Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-04

    ... Vice President, Business Development and Strategy, Communications and Data Services, Comcast 2:35 p.m.: Panel 2: Employing innovative social media, open data and geo-location apps to enhance communications... FEDERAL COMMUNICATIONS COMMISSION Sunshine Act Meetings Open Commission Meeting Wednesday...

  16. 76 FR 28441 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-17

    ...: Vision, Cognition and Pain. Date: June 29-30, 2011. Time: 8 a.m. to 6 p.m. Agenda: To review and evaluate...: Center for Scientific Review Special Emphasis Panel; Member Conflict: Cognition and Central Visual...

  17. 76 FR 35228 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-16

    ... Review Special Emphasis Panel, Small Business: Cancer Diagnostics and Treatments (CDT). Date: July 14-15... Musculoskeletal, Oral, and Skin Systems. Date: July 15, 2011. Time: 8 a.m. to 5 p.m. Agenda: To review and...

  18. 77 FR 50517 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-21

    ...: Neuroimmunity, brain tumors, obesity in aging. Date: September 6, 2012. Time: 11:00 a.m. to 1:00 p.m. Agenda: To... . Name of Committee: Center for Scientific Review Special Emphasis Panel; Member Conflict: Aging, Diet...

  19. 76 FR 32978 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-07

    ... and Alcoholism Special Emphasis Panel; NIAAA Member Conflict Applications--Epidemiology and Behavioral Sciences. Date: June 14, 2011. Time: 11 a.m. to 1 p.m. Agenda: To review and evaluate grant applications...

  20. 77 FR 8270 - Center For Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-14

    ... Committee: Center for Scientific Review Special Emphasis Panel; Fellowships: Sensory and Motor Neuroscience, Cognition and Perception. Date: March 8-9, 2012. Time: 8 a.m. to 5 p.m. Agenda: To review and evaluate grant...

  1. 77 FR 2766 - Arts Advisory Panel Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-19

    ...: Pursuant to Section 10(a)(2) of the Federal Advisory Committee Act (Pub. L. 92-463), as amended, this... Endowment for the Arts. [FR Doc. 2012-1016 Filed 1-13-12; 4:15 pm] BILLING CODE 7537-01-P ...

  2. 76 FR 63664 - Arts Advisory Panel

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-13

    ... 4th, will be closed. Music (application review): November 1-3, 2011 in Room 714. This meeting, from 9... from 9 a.m. to 2 p.m. on November 17th, will be closed. Music (application review): November 15-18...

  3. 78 FR 57866 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-20

    ... Special Emphasis Panel; Risk, Prevention, and Intervention for Addictions Overflow. Date: October 17-18..., Cognition and Perception. Date: October 17-18, 2013 Time: 8:00 a.m. to 5:00 p.m. Agenda: To review and...

  4. 77 FR 32649 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-01

    ... Special Emphasis Panel; Member Conflict: Topics in Bioengineering Sciences and Technology. Date: June 26... Addictions: Overflow. Date: June 28-29, 2012. Time: 8:00 a.m. to 5:00 p.m. Agenda: To review and evaluate...

  5. 77 FR 64818 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-23

    ... of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel; Virtual Reality Technologies for Research and Education in Obesity and Diabetes. Date: November 14, 2012. Time: 6:00 p.m. to 9...

  6. 75 FR 73115 - Center for Scientific Review; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-29

    ... personal privacy. Name of Committee: Center for Scientific Review Special Emphasis Panel, Program Project: Grant in Cell Biology. Date: December 16-17, 2010. Time: 8 a.m. to 6 p.m. Agenda: To review and evaluate...

  7. Synoptic meteorological modes of variability for fine particulate matter (PM2.5) air quality in major metropolitan regions of China

    NASA Astrophysics Data System (ADS)

    Leung, Danny M.; Tai, Amos P. K.; Mickley, Loretta J.; Moch, Jonathan M.; van Donkelaar, Aaron; Shen, Lu; Martin, Randall V.

    2018-05-01

    In his study, we use a combination of multivariate statistical methods to understand the relationships of PM2.5 with local meteorology and synoptic weather patterns in different regions of China across various timescales. Using June 2014 to May 2017 daily total PM2.5 observations from ˜ 1500 monitors, all deseasonalized and detrended to focus on synoptic-scale variations, we find strong correlations of daily PM2.5 with all selected meteorological variables (e.g., positive correlation with temperature but negative correlation with sea-level pressure throughout China; positive and negative correlation with relative humidity in northern and southern China, respectively). The spatial patterns suggest that the apparent correlations with individual meteorological variables may arise from common association with synoptic systems. Based on a principal component analysis of 1998-2017 meteorological data to diagnose distinct meteorological modes that dominate synoptic weather in four major regions of China, we find strong correlations of PM2.5 with several synoptic modes that explain 10 to 40 % of daily PM2.5 variability. These modes include monsoonal flows and cold frontal passages in northern and central China associated with the Siberian High, onshore flows in eastern China, and frontal rainstorms in southern China. Using the Beijing-Tianjin-Hebei (BTH) region as a case study, we further find strong interannual correlations of regionally averaged satellite-derived annual mean PM2.5 with annual mean relative humidity (RH; positive) and springtime fluctuation frequency of the Siberian High (negative). We apply the resulting PM2.5-to-climate sensitivities to the Intergovernmental Panel on Climate Change (IPCC) Coupled Model Intercomparison Project Phase 5 (CMIP5) climate projections to predict future PM2.5 by the 2050s due to climate change, and find a modest decrease of ˜ 0.5 µg m-3 in annual mean PM2.5 in the BTH region due to more frequent cold frontal ventilation under the RCP8.5 future, representing a small climate benefit, but the RH-induced PM2.5 change is inconclusive due to the large inter-model differences in RH projections.

  8. 78 FR 37244 - Proposal Review Panel for Ocean Sciences; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-20

    ... Meeting: Formal fourth year review of the Moorea Coral Reef Long-Term Ecological Research Project. Agenda... Presentations (open). 4:30 p.m.-5:30 p.m.--Demonstrations--Moorea Coral Reef (MCR) dry lab and wet lab (closed...

  9. 75 FR 32489 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-08

    ... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; ARRA--Behavioral Economics C.E.R.--Pilot Research. Date: June 25, 2010. Time: 1 p.m.to 5 p.m. Agenda: To review and evaluate...

  10. 78 FR 6122 - National Institute on Drug Abuse; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-29

    ... Abuse Special Emphasis Panel; Translational Research on Interventions for Adolescents in the Legal System: Trials (U01). Date: March 12, 2013. Time: 8:00 a.m. to 5:00 p.m. Agenda: To review and evaluate...

  11. 78 FR 61376 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-03

    ... Scientific Review Special Emphasis Panel; PAR 12-251: Behavioral Science Track Award for Rapid Transition (B... Sciences. Date: October 30, 2013. Time: 10:00 a.m. to 8:00 p.m. Agenda: To review and evaluate grant...

  12. 78 FR 33853 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-05

    ... Emphasis Panel; Member Conflict: Molecular Genetic Mechanisms. Date: July 3, 2013. Time: 1:00 p.m. to 3:00... Assistance Program Nos. 93.306, Comparative Medicine; 93.333, Clinical Research, 93.306, 93.333, 93.337, 93...

  13. 77 FR 37422 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-21

    ... Scientific Review Special Emphasis Panel; Member Conflict: Diabetes and Obesity. Date: July 17, 2012. Time: 8... Hypertension Member Conflicts. Date: July 17-18, 2012. Time: 9:00 a.m. to 6:00 p.m. Agenda: To review and...

  14. 76 FR 58284 - National Institute of Dental and Craniofacial Research; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-20

    ... Craniofacial Research Special Emphasis Panel; Teleconference Review of Pre Clinical (R34) and Secondary Data Analysis (R03) Applications. Dates: October 18, 2011. Time: 11 a.m. to 1 p.m. Agenda: To review and...

  15. 77 FR 16246 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-20

    ... unwarranted invasion of personal privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel; Omics and Genetic Analysis. Date: April 6, 2012. Time: 8:30 a.m. to 12 p.m. Agenda: To...

  16. 76 FR 31967 - National Institute On Drug Abuse; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-02

    ...: National Institute on Drug Abuse Special Emphasis Panel; Blueprint for Neuroscience Research Science Education Award R25). Date: June 28, 2011. Time: 8 a.m. to 5:30 p.m. Agenda: To review and evaluate grant...

  17. 76 FR 27327 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Combining...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-11

    ... Objective Methods for Quantifying Contact Rates and Mixing Pattern in School-Aged Children, Funding... follows: Time And Date: 11 a.m.-2 p.m., May 3, 2011 (Closed). Place: Teleconference. Contact Person For...

  18. 77 FR 67827 - National Institute of Mental Health Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-14

    ... Emphasis Panel; Novel NeuroAIDS Therapeutics IPCP (P01). Date: November 29, 2012. Time: 12:00 p.m. to 5:00... Awards for Research Training, National Institutes of Health, HHS) Dated: November 6, 2012. Carolyn A...

  19. 78 FR 14560 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-06

    ... Cell Entry. Date: March 27-28, 2013. Time: 10:00 a.m. to 5:00 p.m. Agenda: To review and evaluate grant....gov . Name of Committee: Center for Scientific Review Special Emphasis Panel; Member Conflict: Basic...

  20. Experimental Investigation on Acousto-Ultrasonic Sensing Using Polarization-Maintaining Fiber Bragg Gratings

    NASA Technical Reports Server (NTRS)

    Wang, Gang; Banks, Curtis E.

    2015-01-01

    This report discusses the guided Lamb wave sensing using polarization-maintaining (PM) fiber Bragg grating (PM-FBG) sensor. The goal is to apply the PM-FBG sensor system to composite structural health monitoring (SHM) applications in order to realize directivity and multi-axis strain sensing capabilities while using reduced number of sensors. Comprehensive experiments were conducted to evaluate the performance of the PM-FBG sensor in a composite panel structure under different actuation frequencies and locations. Three Macro-Fiber-Composite (MFC) piezoelectric actuators were used to generate guided Lamb waves and they are oriented at 0, 45, and 90 degrees with respect to PM-FBG axial direction, respectively. The actuation frequency was varied from 20kHz to 200kHz. It is shown that the PM-FBG sensor system is able to detect high-speed ultrasound waves and capture the characteristics under different actuation conditions. Both longitudinal and lateral strain components in the order of nano-strain were determined based on the reflective intensity measurement data from fast and slow axis of the PM fiber. It must be emphasized that this is the first attempt to investigate acousto-ultrasonic sensing using PM-FBG sensor. This could lead to a new sensing approach in the SHM applications.

  1. Experimental Investigation on Acousto-ultrasonic Sensing Using Polarization-Maintaining Fiber Bragg Gratings

    NASA Technical Reports Server (NTRS)

    Wang, Gag; Banks, Curtis E.

    2016-01-01

    This report discusses the guided Lamb wave sensing using polarization-maintaining (PM) fiber Bragg grating (PM-FBG) sensor. The goal is to apply the PM-FBG sensor system to composite structural health monitoring (SHM) applications in order to realize directivity and multi-axis strain sensing capabilities while reducing the number of sensors. Comprehensive experiments were conducted to evaluate the performance of the PM-FBG sensor attached to a composite panel structure under different actuation frequencies and locations. Three Macro-Fiber-Composite (MFC) piezoelectric actuators were used to generate guided Lamb waves that were oriented at 0, 45, and 90 degrees with respect to PM-FBG axial direction, respectively. The actuation frequency was varied from 20kHz to 200kHz. It was shown that the PM-FBG sensor system was able to detect high-speed ultrasound waves and capture the characteristics under different actuation conditions. Both longitudinal and lateral strain components in the order of nano-strain were determined based on the reflective intensity measurement data from fast and slow axis of the PM fiber. It must be emphasized that this is the first attempt to investigate acouto-ultrasonic sensing using PM-FBG sensor. This could lead to a new sensing approach in the SHM applications. Nomenclature.

  2. The relationship between traffic-related air pollutants and cardiac autonomic function in a panel of healthy adults: a further analysis with existing data.

    PubMed

    Wu, Shaowei; Deng, Furong; Niu, Jie; Huang, Qinsheng; Liu, Youcheng; Guo, Xinbiao

    2011-04-01

    Epidemiological studies have linked particulate matter (PM) and carbon monoxide (CO) exposures with alterations in cardiac autonomic function as measured by heart rate variability (HRV) in populations. Recently, we reported association of several HRV indices with marked changes in particulate air pollution around the Beijing 2008 Olympic Games in a panel of healthy adults. We further investigated the cardiac effects of traffic-related air pollutants over wide exposure ranges with expanded data set in this panel of healthy adults. We obtained real-time data on nine taxi drivers' in-car exposures to PM ≤ 2.5 µm in aerodynamic diameter (PM₂.₅) and CO and on multiple HRV indices during a separate daily work shift in four study periods with dramatically changing air pollution levels around the Beijing 2008 Olympic Games. Mixed effect models and a less smoother method were used to investigate the associations of exposures with HRV indices. Results showed overall negative associations of traffic-related air pollutants with HRV indices across periods, as well as differences in period-specific and individual associations. After stratifying the individuals into two different response groups (positive/negative), cardiac effects of air pollutants became stronger within each group. Exposure-response modeling identified changed curvilinear relationships between air pollution exposures and HRV indices with threshold effects. Our results support the association of exposure to traffic-related air pollution with altered cardiac autonomic function in young healthy adults free of cardiovascular compromises. These results suggest a complicated mechanism that traffic-related air pollutants influence the cardiovascular system of healthy adults.

  3. Circulating adhesion molecules after short-term exposure to particulate matter among welders.

    PubMed

    Fang, S C; Eisen, E A; Cavallari, J M; Mittleman, M A; Christiani, D C

    2010-01-01

    Studies from several countries indicate that welders experience increased risk of mortality and morbidity from ischaemic heart disease. Although the underlying mechanisms are unclear, vascular responses to particulate matter contained in welding fumes may play a role. To investigate this, we studied the acute effects of welding fume exposure on the endothelial component of vascular function, as measured by circulating adhesion molecules involved in leukocyte adhesion (sICAM-1 and sVCAM-1) and coagulation (vWF). A panel of 26 male welders was studied repeatedly across a 6 h work-shift on a high exposure welding day and/or a low exposure non-welding day. Personal PM(2.5) exposure was measured throughout the work-shift. Blood samples were collected in the morning (baseline) prior to the exposure period, immediately after the exposure period, and the following morning. To account for the repeated measurements, we used linear mixed models to evaluate the effects of welding (binary) and PM(2.5) (continuous) exposure on each blood marker, adjusting for baseline blood marker concentration, smoking, age and time of day. Welding and PM(2.5) exposure were significantly associated with a decrease in sVCAM-1 in the afternoon and the following morning and an increase in vWF in the afternoon. The data suggest that welding and short-term occupational exposure to PM(2.5) may acutely affect the endothelial component of vascular function.

  4. CuCrZr alloy microstructure and mechanical properties after hot isostatic pressing bonding cycles

    NASA Astrophysics Data System (ADS)

    Frayssines, P.-E.; Gentzbittel, J.-M.; Guilloud, A.; Bucci, P.; Soreau, T.; Francois, N.; Primaux, F.; Heikkinen, S.; Zacchia, F.; Eaton, R.; Barabash, V.; Mitteau, R.

    2014-04-01

    ITER first wall (FW) panels are a layered structure made of the three following materials: 316L(N) austenitic stainless steel, CuCrZr alloy and beryllium. Two hot isostatic pressing (HIP) cycles are included in the reference fabrication route to bond these materials together for the normal heat flux design supplied by the European Union (EU). This reference fabrication route ensures sufficiently good mechanical properties for the materials and joints, which fulfil the ITER mechanical specifications, but often results in a coarse grain size for the CuCrZr alloy, which is not favourable, especially, for the thermal creep properties of the FW panels. To limit the abnormal grain growth of CuCrZr and make the ITER FW fabrication route more reliable, a study began in 2010 in the EU in the frame of an ITER task agreement. Two material fabrication approaches have been investigated. The first one was dedicated to the fabrication of solid CuCrZr alloy in close collaboration with an industrial copper alloys manufacturer. The second approach investigated was the manufacturing of CuCrZr alloy using the powder metallurgy (PM) route and HIP consolidation. This paper presents the main mechanical and microstructural results associated with the two CuCrZr approaches mentioned above. The mechanical properties of solid CuCrZr, PM CuCrZr and joints (solid CuCrZr/solid CuCrZr and solid CuCrZr/316L(N) and PM CuCrZr/316L(N)) are also presented.

  5. Nrf2-related gene expression and exposure to traffic-related air pollution in elderly subjects with cardiovascular disease: An exploratory panel study

    PubMed Central

    Wittkopp, Sharine; Staimer, Norbert; Tjoa, Thomas; Stinchcombe, Timothy; Daher, Nancy; Schauer, James J.; Shafer, Martin M.; Sioutas, Constantinos; Gillen, Daniel L.; Delfino, Ralph J.

    2015-01-01

    Gene expression changes are linked to air pollutant exposures in in vitro and animal experiments. However, limited data are available on how these outcomes relate to ambient air pollutant exposures in humans. We performed an exploratory analysis testing whether gene expression levels were associated with air pollution exposures in a Los Angeles area cohort of elderly subjects with coronary artery disease. Candidate genes (35) were selected from published studies of gene expression-pollutant associations. Expression levels were measured weekly in 43 subjects (≤12 weeks) using quantitative PCR. Exposures included gaseous pollutants O3, nitrogen oxides (NOx), and CO; particulate matter (PM) pollutants elemental and black carbon (EC, BC); and size-fractionated PM mass. We measured organic compounds from PM filter extracts, including polycyclic aromatic hydrocarbons (PAHs), and determined the in vitro oxidative potential of particle extracts. Associations between exposures and gene expression levels were analyzed using mixed-effects regression models. We found positive associations of traffic-related pollutants (EC, BC, primary organic carbon, PM0.25-2.5 PAH and/or PM0.25 PAH, and NOx) with NFE2L2, Nrf2-mediated genes (HMOX1, NQO1, and SOD2), CYP1B1, IL1B, and SELP. Findings suggest that NFE2L2 gene expression links associations of traffic-related air pollution with phase I and II enzyme genes at the promoter transcription level. PMID:25564368

  6. Nrf2-related gene expression and exposure to traffic-related air pollution in elderly subjects with cardiovascular disease: An exploratory panel study.

    PubMed

    Wittkopp, Sharine; Staimer, Norbert; Tjoa, Thomas; Stinchcombe, Timothy; Daher, Nancy; Schauer, James J; Shafer, Martin M; Sioutas, Constantinos; Gillen, Daniel L; Delfino, Ralph J

    2016-01-01

    Gene expression changes are linked to air pollutant exposures in in vitro and animal experiments. However, limited data are available on how these outcomes relate to ambient air pollutant exposures in humans. We performed an exploratory analysis testing whether gene expression levels were associated with air pollution exposures in a Los Angeles area cohort of elderly subjects with coronary artery disease. Candidate genes (35) were selected from published studies of gene expression-pollutant associations. Expression levels were measured weekly in 43 subjects (≤ 12 weeks) using quantitative PCR. Exposures included gaseous pollutants O3, nitrogen oxides (NOx), and CO; particulate matter (PM) pollutants elemental and black carbon (EC, BC); and size-fractionated PM mass. We measured organic compounds from PM filter extracts, including polycyclic aromatic hydrocarbons (PAHs), and determined the in vitro oxidative potential of particle extracts. Associations between exposures and gene expression levels were analyzed using mixed-effects regression models. We found positive associations of traffic-related pollutants (EC, BC, primary organic carbon, PM 0.25-2.5 PAH and/or PM 0.25 PAH, and NOx) with NFE2L2, Nrf2-mediated genes (HMOX1, NQO1, and SOD2), CYP1B1, IL1B, and SELP. Findings suggest that NFE2L2 gene expression links associations of traffic-related air pollution with phase I and II enzyme genes at the promoter transcription level.

  7. KSR2 Is an Essential Regulator of AMP Kinase, Energy Expenditure, and Insulin Sensitivity

    DTIC Science & Technology

    2009-11-04

    Metabolism 10, 366–378, November 4, 2009 ª2009 Elsevier Inc. acyl-CoA molecules into the mitochondria for oxidation. By inhibiting ACC, AMPK inhibits the...bars, n = 8 for each sex) and ksr2!/! mice (dark bars, n = 6 males, n = 11 females) during light (1 p.m.) and dark (9 p.m.) cycles (left panel). (C...impaired by the disruption of ksr2. Respiratory quotient (RQ) is lower in ksr2!/! mice during the dark cycle relative to wild-type mice (Figure 5A and

  8. Panel discussion review: session 1--exposure assessment and related errors in air pollution epidemiologic studies.

    PubMed

    Sarnat, Jeremy A; Wilson, William E; Strand, Matthew; Brook, Jeff; Wyzga, Ron; Lumley, Thomas

    2007-12-01

    Examining the validity of exposure metrics used in air pollution epidemiologic models has been a key focus of recent exposure assessment studies. The objective of this work has been, largely, to determine what a given exposure metric represents and to quantify and reduce any potential errors resulting from using these metrics in lieu of true exposure measurements. The current manuscript summarizes the presentations of the co-authors from a recent EPA workshop, held in December 2006, dealing with the role and contributions of exposure assessment in addressing these issues. Results are presented from US and Canadian exposure and pollutant measurement studies as well as theoretical simulations to investigate what both particulate and gaseous pollutant concentrations represent and the potential errors resulting from their use in air pollution epidemiologic studies. Quantifying the association between ambient pollutant concentrations and corresponding personal exposures has led to the concept of defining attenuation factors, or alpha. Specifically, characterizing pollutant-specific estimates for alpha was shown to be useful in developing regression calibration methods involving PM epidemiologic risk estimates. For some gaseous pollutants such as NO2 and SO2, the associations between ambient concentrations and personal exposures were shown to be complex and still poorly understood. Results from recent panel studies suggest that ambient NO2 measurements may, in some locations, be serving as surrogates to traffic pollutants, including traffic-related PM2.5, hopanes, steranes, and oxidized nitrogen compounds (rather than NO2).

  9. 78 FR 21346 - Emerging Technology and Research Advisory Committee; Notice of Partially Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

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    ...:30 a.m. 1. Opening Remarks. 2. Panel Discussion on Deemed Exports. 3. Emerging Technologies--Results..., April 26 Open Session: 8:30 a.m.-3:30 p.m. 1. Discussion on status of the Export Control Reform...

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    ... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel; K-12 Diabetes Prevention Curriculum Development. Date: June 16, 2010. Time: 9 a.m. to 5 p.m. Agenda: To review and evaluate contract proposals...

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    ... Pathobiology of Cardiovascular and Respiratory Systems. Date: March 26-27, 2013. Time: 8:00 a.m. to 5:00 p.m... Special Emphasis Panel; Member Conflict: Respiratory Diseases. Date: March 26-27, 2013. Time: 9:00 a.m. to...

  17. Development and Implementation of Team-Based Panel Management Tools: Filling the Gap between Patient and Population Information Systems.

    PubMed

    Watts, Brook; Lawrence, Renée H; Drawz, Paul; Carter, Cameron; Shumaker, Amy Hirsch; Kern, Elizabeth F

    2016-08-01

    Effective team-based models of care, such as the Patient-Centered Medical Home, require electronic tools to support proactive population management strategies that emphasize care coordination and quality improvement. Despite the spread of electronic health records (EHRs) and vendors marketing population health tools, clinical practices still may lack the ability to have: (1) local control over types of data collected/reports generated, (2) timely data (eg, up-to-date data, not several months old), and accordingly (3) the ability to efficiently monitor and improve patient outcomes. This article describes a quality improvement project at the hospital system level to develop and implement a flexible panel management (PM) tool to improve care of subpopulations of patients (eg, panels of patients with diabetes) by clinical teams. An in-depth case analysis approach is used to explore barriers and facilitators in building a PM registry tool for team-based management needs using standard data elements (eg, laboratory values, pharmacy records) found in EHRs. Also described are factors that may contribute to sustainability; to date the tool has been adapted to 6 disease-focused subpopulations encompassing more than 200,000 patients. Two key lessons emerged from this initiative: (1) though challenging, team-based clinical end users and information technology needed to work together consistently to refine the product, and (2) locally developed population management tools can provide efficient data tracking for frontline clinical teams and leadership. The preliminary work identified critical gaps that were successfully addressed by building local PM registry tools from EHR-derived data and offers lessons learned for others engaged in similar work. (Population Health Management 2016;19:232-239).

  18. Cardiorespiratory treatments as modifiers of the relationship between particulate matter and health: a case-only analysis on hospitalized patients in Italy

    PubMed Central

    Conti, Sara; Lafranconi, Alessandra; Zanobetti, Antonella; Fornari, Carla; Madotto, Fabiana; Schwartz, Joel; Cesana, Giancarlo

    2016-01-01

    Background A few panel and toxicological studies suggest that health effects of particulate matter (PM) might be modified by medication intake, but whether this modification is confirmed in the general population or for more serious outcomes is still unknown. Objectives We carried out a population-based pilot study in order to assess how pre-hospitalization medical treatments modify the relationship between PM < 10 µm in aerodynamic diameter (PM10) and the risk of cardiorespiratory admission. Methods We gathered information on hospitalizations for cardiorespiratory causes, together with pre-admission pharmacological treatments, that occurred during 2005 in seven cities located in Lombardy (Northern Italy). City-specific PM10 concentrations were measured at fixed monitoring stations. Each treatment of interest was analyzed separately through a case-only approach, using generalized additive models accounting for sex, age, comorbidities, temperature and simultaneous intake of other drugs. Analyses were stratified by season and, if useful, by age and sex. Results Our results showed a higher effect size for PM10 on respiratory admissions in subjects treated with theophylline (Odds Ratio (OR) of treatment for an increment of 10 µg/m3 in PM10 concentration: 1.119; 95% Confidence Interval (CI), 1.013 – 1.237), while for cardiovascular admissions treatment with cardiac therapy (OR: 0.967, 95% CI, 0.940 – 0.995) and lipid modifying agents (OR: 0.962, 95% CI, 0.931 – 0.995) emerged as a protective factor, especially during the warm season. Evidence of a protective effect against the pollutant was found for glucocorticoids and respiratory admissions. Conclusions Our study showed that the treatment with cardiac therapy and lipid modifying agents might mitigate the effect of PM10 on cardiovascular health, while the use of theophylline seems to enhance the effect of the pollutant, possibly due to confounding by indication. It is desirable to extend the analyses to a larger population. PMID:25460671

  19. Acute effects of air pollutants on pulmonary function among students: a panel study in an isolated island.

    PubMed

    Yoda, Yoshiko; Takagi, Hiroshi; Wakamatsu, Junko; Ito, Takeshi; Nakatsubo, Ryouhei; Horie, Yosuke; Hiraki, Takatoshi; Shima, Masayuki

    2017-04-04

    Many epidemiological studies on the health effects of air pollutants have been carried out in regions with major sources such as factories and automobiles. However, the health effects of air pollutants in regions without major sources remain unclear. This study investigated the acute effects of ambient air pollution on pulmonary function among healthy students in an isolated island without major artificial sources of air pollutants. A panel study was conducted of 43 healthy subjects who attended a school in an isolated island in the Seto Inland Sea, Japan. We measured the forced expiratory volume in 1 s (FEV 1 ) and peak expiratory flow (PEF) every morning for about 1 month in May 2014. Ambient concentrations of particulate matter ≤ 2.5 μm in diameter (PM 2.5 ), particulate matter between 2.5 and 10 μm in diameter (PM 10-2.5 ), black carbon (BC), ozone (O 3 ), and nitrogen dioxide (NO 2 ) were measured. The associations between the concentrations of air pollutants and pulmonary function were analyzed using mixed-effects models. A decrease in FEV 1 was significantly associated with BC concentrations (-27.28 mL [95%confidence interval (CI):-54.10,-0.46] for an interquartile range (IQR) increase of 0.23 μg/m 3 ). The decrease in PEF was significantly associated with indoor O 3 concentrations (-8.03 L/min [95% CI:-13.02,-3.03] for an IQR increase of 11 ppb). Among subjects with a history of allergy, an increase in PM 2.5 concentrations was significantly associated with low FEV 1 . In subjects with a history of asthma, an inverse association between the indoor O 3 concentration and pulmonary function was observed. Our results demonstrate that increases in BC and O 3 concentrations have acute effects on the pulmonary function among students in an isolated island without major artificial sources of air pollutants.

  20. PM10 source apportionment in a Swiss Alpine valley impacted by highway traffic.

    PubMed

    Ducret-Stich, Regina E; Tsai, Ming-Yi; Thimmaiah, Devraj; Künzli, Nino; Hopke, Philip K; Phuleria, Harish C

    2013-09-01

    Although trans-Alpine highway traffic exhaust is one of the major sources of air pollution along the highway valleys of the Alpine regions, little is known about its contribution to residential exposure and impact on respiratory health. In this paper, source-specific contributions to particulate matter with an aerodynamic diameter < 10 μm (PM10) and their spatio-temporal distribution were determined for later use in a pediatric asthma panel study in an Alpine village. PM10 sources were identified by positive matrix factorization using chemical trace elements, elemental, and organic carbon from daily PM10 filters collected between November 2007 and June 2009 at seven locations within the village. Of the nine sources identified, four were directly road traffic-related: traffic exhaust, road dust, tire and brake wear, and road salt contributing 16 %, 8 %, 1 %, and 2 % to annual PM10 concentrations, respectively. They showed a clear dependence with distance to highway. Additional contributions were identified from secondary particles (27 %), biomass burning (18 %), railway (11 %), and mineral dust including a local construction site (13 %). Comparing these source contributions with known source-specific biomarkers (e.g., levoglucosan, nitro-polycyclic aromatic hydrocarbons) showed high agreement with biomass burning, moderate with secondary particles (in winter), and lowest agreement with traffic exhaust.

  1. Acute decrease in HDL cholesterol associated with exposure to welding fumes.

    PubMed

    Rice, Mary Berlik; Cavallari, Jenn; Fang, Shona; Christiani, David

    2011-01-01

    To investigate acute changes in circulating lipids after exposure to relatively high levels of particulate matter through welding. Using a repeated measures panel study, lipid levels before and after welding and personal exposures to fine particulate matter (PM2.5) were measured in 36 male welders over 63 exposure and/or control days. There was a trend toward decrease in HDL (-2.3 mg/dL, P = 0.08) 18 hours after welding. This effect became significant (-2.6 mg/dL, P = 0.05) after adjustment for possible confounders. The effect was strongest (-4.3 mg/dL, P = 0.02) among welders who did not weld the day before the study. There were no significant changes in other lipids associated with welding or PM2.5 exposure. Welding exposure was associated with an acute decrease in circulating HDL, which may relate to the inflammatory and proatherosclerotic effects of fine particle exposure.

  2. PM2.5 AND HEART RATE VARIABILITY IN AN ELDERLY PANEL. (R826780)

    EPA Science Inventory

    The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Concl...

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  4. 75 FR 7486 - Center for Scientific Review; Notice of Closed Meetings

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    2010-02-19

    ... Business: Cell Biology and Molecular Imaging. Date: March 11, 2010. Time: 8 a.m. to 6 p.m. Agenda: To... Panel, Genetics and Epigenetics in Health and Disease. Date: March 12-13, 2010. Time: 9 a.m. to 11 a.m...

  5. 75 FR 54160 - National Institute on Aging; Notice of Closed Meetings

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    ... Sleep Disorders. Date: October 13, 2010. Time: 8:30 a.m. to 11 a.m. Agenda: To review and evaluate grant... Emphasis Panel; Long-term Effects of Early Education. Date: October 22, 2010. Time: 10 a.m. to 1 p.m...

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    ... Committee Management Officer, National Endowment for the Humanities, Washington, DC 20506; telephone (202..., 2011. Time: 9 a.m. to 5 p.m. Location: Room 315. Program: This meeting will review applications for Landmark Workshops for School Teachers and Community College Faculty, submitted to the Division of...

  7. Possible Mediation by Methylation in Acute Inflammation Following Personal Exposure to Fine Particulate Air Pollution

    PubMed Central

    Wang, Cuicui; Chen, Renjie; Shi, Min; Cai, Jing; Shi, Jingjin; Yang, Changyuan; Li, Huichu; Lin, Zhijing; Meng, Xia; Liu, Cong; Niu, Yue; Xia, Yongjie; Zhao, Zhuohui; Kan, Haidong; Weinberg, Clarice R

    2018-01-01

    Abstract Air pollution may increase cardiovascular and respiratory risk through inflammatory pathways, but evidence for acute effects has been weak and indirect. Between December 2014 and July 2015, we enrolled 36 healthy, nonsmoking college students for a panel study in Shanghai, China, a city with highly variable levels of air pollution. We measured personal exposure to particulate matter with an aerodynamic diameter less than or equal to 2.5 μm (PM2.5) continuously for 72 hours preceding each of 4 clinical visits that included phlebotomy. We measured 4 inflammation proteins and DNA methylation at nearby regulatory cytosine-phosphate-guanine (CpG) loci. We applied linear mixed-effect models to examine associations over various lag times. When results suggested mediation, we evaluated methylation as mediator. Increased PM2.5 concentration was positively associated with all 4 inflammation proteins and negatively associated with DNA methylation at regulatory loci for tumor necrosis factor alpha (TNF-α) and soluble intercellular adhesion molecule-1. A 10-μg/m3 increase in average PM2.5 during the 24 hours preceding blood draw corresponded to a 4.4% increase in TNF-α and a statistically significant decrease in methylation at one of the two studied candidate CpG loci for TNF-α. Epigenetics may play an important role in mediating effects of PM2.5 on inflammatory pathways. PMID:29020142

  8. 78 FR 13359 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed...

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    ... Institute of Child Health and Human Development Special Emphasis Panel; Global Partnership for Social Science AIDS Research (R24). Date: March 21-22, 2013. Time: 8:00 a.m. to 5:00 p.m. Agenda: To review and...

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  14. [The correlations between air quality and heart rate variability in aged susceptible people during Beijing Olympic Games 2008].

    PubMed

    Jia, Yu-ping; Guo, Yu-ming; Wang, Zhen-yu; Xie, Yong-zhen; Tang, Xiao-yan; Zhu, Tong; Wang, Sheng; Pan, Xiao-chuan

    2009-08-01

    To observe the variations of the concentrations of air pollutants and explore the correlation between the heart rate variability (HRV) of the aged people and the air quality during Beijing Olympic Games 2008. A panel study design was adopted. A total of twenty-six over 55-year-old patients with coronary heart disease or angina pectoris or a symptom of myocardial ischemia at least for one year were enrolled as a panel and followed up five times by measuring HRV index and other related indexes from June to September in 2008. The correlations between the HRV of the aged people and the air quality was analyzed with the linear mixed-effect models according to the data of air pollutants and meteorological conditions collected simultaneously from Beijing Environmental Protection Bureau and Beijing Meteorological Bureau. In single-pollutant mixed-effect models, the significant correlation was observed in the reduction of ambient PM(10), SO(2) and NO(2) with the improvement of the total power and high-frequency power (HF) of HRV in the panel subjects, and a 10 microg/m(3) decrease in PM(10), SO(2) and NO(2) level was correlated with 2.51% (95%CI: -3.80% - -1.22%, t = -1.99, P = 0.0497), 31.39% (95%CI: -52.24% - -10.53%, t = -1.99, P = 0.0497) and 42.72% (95%CI: -75.06% - -10.38%, t = -1.99, P = 0.0497) rises in total power of HRV respectively. A 10 microg/m(3) decrease in PM(10), SO(2) and NO(2) level was correlated with 3.46% (95%CI: -5.14% - -1.77%, t = -2.11, P = 0.0378), 40.63% (95%CI: -68.70% - -12.56%, t = -2.11, P = 0.0378) and 53.76% (95%CI: -97.97% - -9.56%, t = -2.11, P = 0.0378) rises in high-frequency power (HF) of HRV respectively. It suggests that the air pollution reduction could improve the cardiovascular functions of the susceptible population.

  15. 2005 Net Centric Operations, Interoperability and Systems Integration Conference - Facilitating Net Centric Operations and Warfare

    DTIC Science & Technology

    2005-03-24

    1 :45PM- 3 :30PM Panel: Establishing a Business Mission Area in the Department of...Minimum MaximumLEVEL OF INTEROPERABILITY Level 1 Level 2 Level 3 Level 4 10 COTS Native IP Network IP TCP UDP Network QoS Layer IIOP NTP SNMP Legacy...2005 Page 1 3 /27/2005 Page 2 3 /27/2005 Page 3 3 /27/2005 Page 4 3 /27/2005 Page 5 3 /27/2005 Page 6 3 /27/2005 Page 7 3 /27/2005 Page 8 3 /27/2005 Page 9 3

  16. Cardiovascular effects of air pollution.

    PubMed

    Brook, Robert D

    2008-09-01

    Air pollution is a heterogeneous mixture of gases, liquids and PM (particulate matter). In the modern urban world, PM is principally derived from fossil fuel combustion with individual constituents varying in size from a few nanometres to 10 microm in diameter. In addition to the ambient concentration, the pollution source and chemical composition may play roles in determining the biological toxicity and subsequent health effects. Nevertheless, studies from across the world have consistently shown that both short- and long-term exposures to PM are associated with a host of cardiovascular diseases, including myocardial ischaemia and infarctions, heart failure, arrhythmias, strokes and increased cardiovascular mortality. Evidence from cellular/toxicological experiments, controlled animal and human exposures and human panel studies have demonstrated several mechanisms by which particle exposure may both trigger acute events as well as prompt the chronic development of cardiovascular diseases. PM inhaled into the pulmonary tree may instigate remote cardiovascular health effects via three general pathways: instigation of systemic inflammation and/or oxidative stress, alterations in autonomic balance, and potentially by direct actions upon the vasculature of particle constituents capable of reaching the systemic circulation. In turn, these responses have been shown to trigger acute arterial vasoconstriction, endothelial dysfunction, arrhythmias and pro-coagulant/thrombotic actions. Finally, long-term exposure has been shown to enhance the chronic genesis of atherosclerosis. Although the risk to one individual at any single time point is small, given the prodigious number of people continuously exposed, PM air pollution imparts a tremendous burden to the global public health, ranking it as the 13th leading cause of morality (approx. 800,000 annual deaths).

  17. Source-specific fine particulate air pollution and systemic inflammation in ischaemic heart disease patients

    PubMed Central

    Siponen, Taina; Yli-Tuomi, Tarja; Aurela, Minna; Dufva, Hilkka; Hillamo, Risto; Hirvonen, Maija-Riitta; Huttunen, Kati; Pekkanen, Juha; Pennanen, Arto; Salonen, Iiris; Tiittanen, Pekka; Salonen, Raimo O; Lanki, Timo

    2015-01-01

    Objective To compare short-term effects of fine particles (PM2.5; aerodynamic diameter <2.5 µm) from different sources on the blood levels of markers of systemic inflammation. Methods We followed a panel of 52 ischaemic heart disease patients from 15 November 2005 to 21 April 2006 with clinic visits in every second week in the city of Kotka, Finland, and determined nine inflammatory markers from blood samples. In addition, we monitored outdoor air pollution at a fixed site during the study period and conducted a source apportionment of PM2.5 using the Environmental Protection Agency's model EPA PMF 3.0. We then analysed associations between levels of source-specific PM2.5 and markers of systemic inflammation using linear mixed models. Results We identified five source categories: regional and long-range transport (LRT), traffic, biomass combustion, sea salt, and pulp industry. We found most evidence for the relation of air pollution and inflammation in LRT, traffic and biomass combustion; the most relevant inflammation markers were C-reactive protein, interleukin-12 and myeloperoxidase. Sea salt was not positively associated with any of the inflammatory markers. Conclusions Results suggest that PM2.5 from several sources, such as biomass combustion and traffic, are promoters of systemic inflammation, a risk factor for cardiovascular diseases. PMID:25479755

  18. 75 FR 33626 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

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    ... Comparative Effectiveness Research in Clinical Hypertension Management. Date: June 24, 2010. Time: 12 p.m. to... Institute Special Emphasis Panel. Ruth L. Kirschstein NRSA Institutional Research Training Grants. Date... Domestic Assistance Program Nos. 93.233, National Center for Sleep Disorders Research; 93.837, Heart and...

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    ... Psychology in Fellowships, submitted to the Division of Research Programs at the May 4, 2010 deadline. 21... applications for Advanced Social Science Research on Japan in Fellowships, submitted to the Division of...:30 a.m. to 5 p.m. Room: 415. Program: This meeting will review applications for Social Sciences and...

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