Noise characteristics analysis of short wave infrared InGaAs focal plane arrays
NASA Astrophysics Data System (ADS)
Yu, Chunlei; Li, Xue; Yang, Bo; Huang, Songlei; Shao, Xiumei; Zhang, Yaguang; Gong, Haimei
2017-09-01
The increasing application of InGaAs short wave infrared (SWIR) focal plane arrays (FPAs) in low light level imaging requires ultra-low noise FPAs. This paper presents the theoretical analysis of FPA noise, and point out that both dark current and detector capacitance strongly affect the FPA noise. The impact of dark current and detector capacitance on FPA noise is compared in different situations. In order to obtain low noise performance FPAs, the demand for reducing detector capacitance is higher especially when pixel pitch is smaller, integration time is shorter, and integration capacitance is larger. Several InGaAs FPAs were measured and analyzed, the experiments' results could be well fitted to the calculated results. The study found that the major contributor of FPA noise is coupled noise with shorter integration time. The influence of detector capacitance on FPA noise is more significant than that of dark current. To investigate the effect of detector performance on FPA noise, two kinds of photodiodes with different concentration of the absorption layer were fabricated. The detectors' performance and noise characteristics were measured and analyzed, the results are consistent with that of theoretical analysis.
NASA Technical Reports Server (NTRS)
Avila, Edwin M. Martinez; Muniz, Ricardo; Szafran, Jamie; Dalton, Adam
2011-01-01
Lines of code (LOC) analysis is one of the methods used to measure programmer productivity and estimate schedules of programming projects. The Launch Control System (LCS) had previously used this method to estimate the amount of work and to plan development efforts. The disadvantage of using LOC as a measure of effort is that one can only measure 30% to 35% of the total effort of software projects involves coding [8]. In the application, instead of using the LOC we are using function point for a better estimation of hours in each software to develop. Because of these disadvantages, Jamie Szafran of the System Software Branch of Control And Data Systems (NE-C3) at Kennedy Space Canter developed a web application called Function Point Analysis (FPA) Depot. The objective of this web application is that the LCS software architecture team can use the data to more accurately estimate the effort required to implement customer requirements. This paper describes the evolution of the domain model used for function point analysis as project managers continually strive to generate more accurate estimates.
Patel, Nitesh V; Sundararajan, Sri; Keller, Irwin; Danish, Shabbar
2018-01-01
Objective: Magnetic resonance (MR)-guided stereotactic laser amygdalohippocampectomy is a minimally invasive procedure for the treatment of refractory epilepsy in patients with mesial temporal sclerosis. Limited data exist on post-ablation volumetric trends associated with the procedure. Methods: 10 patients with mesial temporal sclerosis underwent MR-guided stereotactic laser amygdalohippocampectomy. Three independent raters computed ablation volumes at the following time points: pre-ablation (PreA), immediate post-ablation (IPA), 24 hours post-ablation (24PA), first follow-up post-ablation (FPA), and greater than three months follow-up post-ablation (>3MPA), using OsiriX DICOM Viewer (Pixmeo, Bernex, Switzerland). Statistical trends in post-ablation volumes were determined for the time points. Results: MR-guided stereotactic laser amygdalohippocampectomy produces a rapid rise and distinct peak in post-ablation volume immediately following the procedure. IPA volumes are significantly higher than all other time points. Comparing individual time points within each raters dataset (intra-rater), a significant difference was seen between the IPA time point and all others. There was no statistical difference between the 24PA, FPA, and >3MPA time points. A correlation analysis demonstrated the strongest correlations at the 24PA (r=0.97), FPA (r=0.95), and 3MPA time points (r=0.99), with a weaker correlation at IPA (r=0.92). Conclusion: MR-guided stereotactic laser amygdalohippocampectomy produces a maximal increase in post-ablation volume immediately following the procedure, which decreases and stabilizes at 24 hours post-procedure and beyond three months follow-up. Based on the correlation analysis, the lower inter-rater reliability at the IPA time point suggests it may be less accurate to assess volume at this time point. We recommend post-ablation volume assessments be made at least 24 hours post-selective ablation of the amygdalohippocampal complex (SLAH).
2013-01-01
Background The relationship between torsional bony deformities and rotational gait parameters has not been sufficiently investigated. This study was to investigate the degree of contribution of torsional bony deformities to rotational gait parameters in patients with diplegic cerebral palsy (CP). Methods Thirty three legs from 33 consecutive ambulatory patients (average age 9.5 years, SD 6.9 years; 20 males and 13 females) with diplegic CP who underwent preoperative three dimensional gait analysis, foot radiographs, and computed tomography (CT) were included. Adjusted foot progression angle (FPA) was retrieved from gait analysis by correcting pelvic rotation from conventional FPA, which represented the rotational gait deviation of the lower extremity from the tip of the femoral head to the foot. Correlations between rotational gait parameters (FPA, adjusted FPA, average pelvic rotation, average hip rotation, and average knee rotation) and radiologic measurements (acetabular version, femoral anteversion, knee torsion, tibial torsion, and anteroposteriortalo-first metatarsal angle) were analyzed. Multiple regression analysis was performed to identify significant contributing radiographic measurements to adjusted FPA. Results Adjusted FPA was significantly correlated with FPA (r=0.837, p<0.001), contralateral FPA (r=0.492, p=0.004), pelvic rotation during gait (r=−0.489, p=0.004), knee rotation during gait (r=0.376, p=0.031), and femoral anteversion (r=0.350, p=0.046). In multiple regression analysis, femoral anteversion (p=0.026) and tibial torsion (p=0.034) were found to be the significant contributing structural deformities to the adjusted FPA (R2=0.247). Conclusions Femoral anteversion and tibial torsion were found to be the significant structural deformities that could affect adjusted FPA in patients with diplegic CP. Femoral anteversion and tibial torsion could explain only 24.7% of adjusted FPA. PMID:23767833
Yu, Jianwei; An, Wei; Cao, Nan; Yang, Min; Gu, Junong; Zhang, Dong; Lu, Ning
2014-07-01
Taste and odor (T/O) in drinking water often cause consumer complaints and are thus regulated in many countries. However, people in different regions may exhibit different sensitivities toward T/O. This study proposed a method to determine the regional drinking water odorant regulation goals (ORGs) based on the odor sensitivity distribution of the local population. The distribution of odor sensitivity to 2-methylisoborneol (2-MIB) by the local population in Beijing, China was revealed by using a normal distribution function/model to describe the odor complaint response to a 2-MIB episode in 2005, and a 2-MIB concentration of 12.9 ng/L and FPA (flavor profile analysis) intensity of 2.5 was found to be the critical point to cause odor complaints. Thus the Beijing ORG for 2-MIB was determined to be 12.9 ng/L. Based on the assumption that the local FPA panel can represent the local population in terms of sensitivity to odor, and that the critical FPA intensity causing odor complaints was 2.5, this study tried to determine the ORGs for seven other cities of China by performing FPA tests using an FPA panel from the corresponding city. ORG values between 12.9 and 31.6 ng/L were determined, showing that a unified ORG may not be suitable for drinking water odor regulations. This study presents a novel approach for setting drinking water odor regulations. Copyright © 2014. Published by Elsevier B.V.
Tracking initially unresolved thrusting objects in 3D using a single stationary optical sensor
NASA Astrophysics Data System (ADS)
Lu, Qin; Bar-Shalom, Yaakov; Willett, Peter; Granström, Karl; Ben-Dov, R.; Milgrom, B.
2017-05-01
This paper considers the problem of estimating the 3D states of a salvo of thrusting/ballistic endo-atmospheric objects using 2D Cartesian measurements from the focal plane array (FPA) of a single fixed optical sensor. Since the initial separations in the FPA are smaller than the resolution of the sensor, this results in merged measurements in the FPA, compounding the usual false-alarm and missed-detection uncertainty. We present a two-step methodology. First, we assume a Wiener process acceleration (WPA) model for the motion of the images of the projectiles in the optical sensor's FPA. We model the merged measurements with increased variance, and thence employ a multi-Bernoulli (MB) filter using the 2D measurements in the FPA. Second, using the set of associated measurements for each confirmed MB track, we formulate a parameter estimation problem, whose maximum likelihood estimate can be obtained via numerical search and can be used for impact point prediction. Simulation results illustrate the performance of the proposed method.
Hubbard, Logan; Lipinski, Jerry; Ziemer, Benjamin; Malkasian, Shant; Sadeghi, Bahman; Javan, Hanna; Groves, Elliott M; Dertli, Brian; Molloi, Sabee
2018-01-01
Purpose To retrospectively validate a first-pass analysis (FPA) technique that combines computed tomographic (CT) angiography and dynamic CT perfusion measurement into one low-dose examination. Materials and Methods The study was approved by the animal care committee. The FPA technique was retrospectively validated in six swine (mean weight, 37.3 kg ± 7.5 [standard deviation]) between April 2015 and October 2016. Four to five intermediate-severity stenoses were generated in the left anterior descending artery (LAD), and 20 contrast material-enhanced volume scans were acquired per stenosis. All volume scans were used for maximum slope model (MSM) perfusion measurement, but only two volume scans were used for FPA perfusion measurement. Perfusion measurements in the LAD, left circumflex artery (LCx), right coronary artery, and all three coronary arteries combined were compared with microsphere perfusion measurements by using regression, root-mean-square error, root-mean-square deviation, Lin concordance correlation, and diagnostic outcomes analysis. The CT dose index and size-specific dose estimate per two-volume FPA perfusion measurement were also determined. Results FPA and MSM perfusion measurements (P FPA and P MSM ) in all three coronary arteries combined were related to reference standard microsphere perfusion measurements (P MICRO ), as follows: P FPA_COMBINED = 1.02 P MICRO_COMBINED + 0.11 (r = 0.96) and P MSM_COMBINED = 0.28 P MICRO_COMBINED + 0.23 (r = 0.89). The CT dose index and size-specific dose estimate per two-volume FPA perfusion measurement were 10.8 and 17.8 mGy, respectively. Conclusion The FPA technique was retrospectively validated in a swine model and has the potential to be used for accurate, low-dose vessel-specific morphologic and physiologic assessment of coronary artery disease. © RSNA, 2017.
Liang, Kun; Yang, Cailan; Peng, Li; Zhou, Bo
2017-02-01
In uncooled long-wave IR camera systems, the temperature of a focal plane array (FPA) is variable along with the environmental temperature as well as the operating time. The spatial nonuniformity of the FPA, which is partly affected by the FPA temperature, obviously changes as well, resulting in reduced image quality. This study presents a real-time nonuniformity correction algorithm based on FPA temperature to compensate for nonuniformity caused by FPA temperature fluctuation. First, gain coefficients are calculated using a two-point correction technique. Then offset parameters at different FPA temperatures are obtained and stored in tables. When the camera operates, the offset tables are called to update the current offset parameters via a temperature-dependent interpolation. Finally, the gain coefficients and offset parameters are used to correct the output of the IR camera in real time. The proposed algorithm is evaluated and compared with two representative shutterless algorithms [minimizing the sum of the squares of errors algorithm (MSSE), template-based solution algorithm (TBS)] using IR images captured by a 384×288 pixel uncooled IR camera with a 17 μm pitch. Experimental results show that this method can quickly trace the response drift of the detector units when the FPA temperature changes. The quality of the proposed algorithm is as good as MSSE, while the processing time is as short as TBS, which means the proposed algorithm is good for real-time control and at the same time has a high correction effect.
Read-noise characterization of focal plane array detectors via mean-variance analysis.
Sperline, R P; Knight, A K; Gresham, C A; Koppenaal, D W; Hieftje, G M; Denton, M B
2005-11-01
Mean-variance analysis is described as a method for characterization of the read-noise and gain of focal plane array (FPA) detectors, including charge-coupled devices (CCDs), charge-injection devices (CIDs), and complementary metal-oxide-semiconductor (CMOS) multiplexers (infrared arrays). Practical FPA detector characterization is outlined. The nondestructive readout capability available in some CIDs and FPA devices is discussed as a means for signal-to-noise ratio improvement. Derivations of the equations are fully presented to unify understanding of this method by the spectroscopic community.
Stent Design Affects Femoropopliteal Artery Deformation.
MacTaggart, Jason; Poulson, William; Seas, Andreas; Deegan, Paul; Lomneth, Carol; Desyatova, Anastasia; Maleckis, Kaspars; Kamenskiy, Alexey
2018-03-23
Poor durability of femoropopliteal artery (FPA) stenting is multifactorial, and severe FPA deformations occurring with limb flexion are likely involved. Different stent designs result in dissimilar stent-artery interactions, but the degree of these effects in the FPA is insufficiently understood. To determine how different stent designs affect limb flexion-induced FPA deformations. Retrievable markers were deployed into n = 28 FPAs of lightly embalmed human cadavers. Bodies were perfused and CT images were acquired with limbs in the standing, walking, sitting, and gardening postures. Image analysis allowed measurement of baseline FPA foreshortening, bending, and twisting associated with each posture. Markers were retrieved and 7 different stents were deployed across the adductor hiatus in the same limbs. Markers were then redeployed in the stented FPAs, and limbs were reimaged. Baseline and stented FPA deformations were compared to determine the influence of each stent design. Proximal to the stent, Innova, Supera, and SmartFlex exacerbated foreshortening, SmartFlex exacerbated twisting, and SmartControl restricted bending of the FPA. Within the stent, all devices except Viabahn restricted foreshortening; Supera, SmartControl, and AbsolutePro restricted twisting; SmartFlex and Innova exacerbated twisting; and Supera and Viabahn restricted bending. Distal to the stents, all devices except AbsolutePro and Innova exacerbated foreshortening, and Viabahn, Supera, Zilver, and SmartControl exacerbated twisting. All stents except Supera were pinched in flexed limb postures. Peripheral self-expanding stents significantly affect limb flexion-induced FPA deformations, but in different ways. Although certain designs seem to accommodate some deformation modes, no device was able to match all FPA deformations.
Sánchez-Villalobos, Alfredo; Urdaneta-Fernández, Margelys; Rubio-Fuenmayor, Elí; Molero-Saras, Gladys; Luzardo-Charris, Carlos; Corona-Mengual, Carlos
2011-03-01
In order to show the development and scope of a serological analysis method based on fluorescence polarization assay (FPA) from a drop of blood obtained by the capillary technique, a Brucella antibody assay was performed on a group of 321 high-risk workers. The results were compared with data from the analysis of blood serum by FPA and a competitive enzyme immunoassay (ELISA-c). The number of concordance was 318 (99.06%), and discordant 3 (0.93%), which were negative in serum by fluorescence polarization (FPAs) and ELISA-c, but positive with capillary FPA (FPAc). The comparative results FPAc were: sensitivity 100%; specificity: 99.05%; positive predictive value 66.67%; negative predictive value 100.0%; false positive rate: 0.95%; false negative rate: 0%; accuracy: 98.0%; odds ratio: 203.00. The youden J for both FPA methods was 0.667. The identification was considered reliable and the correlation of both procedures, FPA and ELISA-c, was no statistically different (P > 0.05%), which allows to highly recommend the study implementation of human brucellosis with capillary blood as a preliminary method.
Preparation of folate-modified pullulan acetate nanoparticles for tumor-targeted drug delivery.
Zhang, Hui-zhu; Li, Xue-min; Gao, Fu-ping; Liu, Ling-rong; Zhou, Zhi-min; Zhang, Qi-qing
2010-01-01
The purpose of this work was to develop a novel nano-carrier with targeting property to tumor. In this study, pullulan acetate (PA) was synthesized by the acetylation of pullulan to simplify the preparation technique of nanoparticles. Folic acid (FA) was conjugated to PA in order to improve the cancer-targeting activity. The products were characterized by proton nuclear magnetic resonance (¹H NMR) spectroscopy. Epirubicin-loaded nanoparticles were prepared by a solvent diffusion method. The loading efficiencies and EPI content increased with the amount of triethylamine (TEA) increasing in some degree. FPA nanoparticles could incorporate more epirubicin than PA nanoparticles. The folate-modified PA nanoparticles (FPA/EPI NPs) exhibited faster drug release than PA nanoparticles (PA/EPI NPs) in vitro. Confocal image analysis and flow cytometry test revealed that FPA/EPI NPs exhibited a greater extent of cellular uptake than PA/EPI NPs against KB cells over-expressing folate receptors on the surface. FPA/EPI NPs also showed higher cytotoxicity than PA/EPI NPs. The cytotoxic effect of FPA/EPI NPs to KB cells was inhibited by an excess amount of folic acid, suggesting that the binding and/or uptake were mediated by the folate receptor.
Hyperglycemia may determine fibrinopeptide A plasma level increase in humans.
Ceriello, A; Giugliano, D; Quatraro, A; Dello Russo, P; Marchi, E; Torella, R
1989-12-01
The effects of hyperglycemia on plasma fibrinopeptide A (FPA) levels in normal subjects are reported. An increase of FPA concentration parallel to sustained hyperglycemia was observed; when the glycemia returned to basal values, FPA showed values in normal range. Heparin infusion was able to significantly decrease the hyperglycemia-induced augment of FPA levels. Isovolumic-isotonic NaCl solution infusion produced a slight (NS) increase in FPA levels; however, mild hyperglycemia, achieved by glucagon, was also able to produce a significant increase in FPA concentration. These data demonstrate the direct role of hyperglycemia in conditioning FPA level, and suggest that hyperglycemia, by itself, is a sufficient stimulus to produce thrombin activation in humans.
A Hybrid, Large-Scale Wireless Sensor Network for Real-Time Acquisition and Tracking
2007-06-01
multicolor, Quantum Well Infrared Photodetector ( QWIP ), step-stare, large-format Focal Plane Array (FPA) is proposed and evaluated through performance...Photodetector ( QWIP ), step-stare, large-format Focal Plane Array (FPA) is proposed and evaluated through performance analysis. The thesis proposes...7 1. Multi-color IR Sensors - Operational Advantages ...........................8 2. Quantum-Well IR Photodetector ( QWIP
Strategies for Choosing Descent Flight-Path Angles for Small Jets
NASA Technical Reports Server (NTRS)
Wu, Minghong Gilbert; Green, Steven M.
2012-01-01
Three candidate strategies for choosing the descent flight path angle (FPA) for small jets are proposed, analyzed, and compared for fuel efficiency under arrival metering conditions. The strategies vary in operational complexity from a universally fixed FPA, or FPA function that varies with descent speed for improved fuel efficiency, to the minimum-fuel FPA computed for each flight based on winds, route, and speed profile. Methodologies for selecting the parameter for the first two strategies are described. The differences in fuel burn are analyzed over a year s worth of arrival traffic and atmospheric conditions recorded for the Dallas/Fort Worth (DFW) Airport during 2011. The results show that the universally fixed FPA strategy (same FPA for all flights, all year) burns on average 26 lbs more fuel per flight as compared to the minimum-fuel solution. This FPA is adapted to the arrival gate (direction of entry to the terminal) and various timespans (season, month and day) to improve fuel efficiency. Compared to a typical FPA of approximately 3 degrees the adapted FPAs vary significantly, up to 1.3 from one arrival gate to another or up to 1.4 from one day to another. Adapting the universally fixed FPA strategy to the arrival gate or to each day reduces the extra fuel burn relative to the minimum-fuel solution by 27% and 34%, respectively. The adaptations to gate and time combined shows up to 57% reduction of the extra fuel burn. The second strategy, an FPA function, contributes a 17% reduction in the 26 lbs of extra fuel burn over the universally fixed FPA strategy. Compared to the corresponding adaptations of the universally fixed FPA, adaptations of the FPA function reduce the extra fuel burn anywhere from 15-23% depending on the extent of adaptation. The combined effect of the FPA function strategy with both directional and temporal adaptation recovers 67% of the extra fuel relative to the minimum-fuel solution.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hubbard, L; Ziemer, B; Sadeghi, B
Purpose: To evaluate the accuracy of dynamic CT myocardial perfusion measurement using first pass analysis (FPA) and maximum slope models. Methods: A swine animal model was prepared by percutaneous advancement of an angioplasty balloon into the proximal left anterior descending (LAD) coronary artery to induce varying degrees of stenosis. Maximal hyperaemia was achieved in the LAD with an intracoronary adenosine drip (240 µg/min). Serial microsphere and contrast (370 mg/mL iodine, 30 mL, 5mL/s) injections were made over a range of induced stenoses, and dynamic imaging was performed using a 320-row CT scanner at 100 kVp and 200 mA. The FPAmore » CT perfusion technique was used to make vessel-specific myocardial perfusion measurements. CT perfusion measurements using the FPA and maximum slope models were validated using colored microspheres as the reference gold standard. Results: Perfusion measurements using the FPA technique (P-FPA) showed good correlation with minimal offset when compared to perfusion measurements using microspheres (P- Micro) as the reference standard (P -FPA = 0.96 P-Micro + 0.05, R{sup 2} = 0.97, RMSE = 0.19 mL/min/g). In contrast, the maximum slope model technique (P-MS) was shown to underestimate perfusion when compared to microsphere perfusion measurements (P-MS = 0.42 P -Micro −0.48, R{sup 2} = 0.94, RMSE = 3.3 mL/min/g). Conclusion: The results indicate the potential for significant improvements in accuracy of dynamic CT myocardial perfusion measurement using the first pass analysis technique as compared with the standard maximum slope model.« less
Cantwell, Kate; Morgans, Amee; Smith, Karen; Livingston, Michael; Dietze, Paul
2014-02-01
This paper aims to examine whether an adaptation of the International Classification of Disease (ICD) coding system can be applied retrospectively to final paramedic assessment data in an ambulance dataset with a view to developing more fine-grained, clinically relevant case definitions than are available through point-of-call data. Over 1.2 million case records were extracted from the Ambulance Victoria data warehouse. Data fields included dispatch code, cause (CN) and final primary assessment (FPA). Each FPA was converted to an ICD-10-AM code using word matching or best fit. ICD-10-AM codes were then converted into Major Diagnostic Categories (MDC). CN was aligned with the ICD-10-AM codes for external cause of morbidity and mortality. The most accurate results were obtained when ICD-10-AM codes were assigned using information from both FPA and CN. Comparison of cases coded as unconscious at point-of-call with the associated paramedic assessment highlighted the extra clinical detail obtained when paramedic assessment data are used. Ambulance paramedic assessment data can be aligned with ICD-10-AM and MDC with relative ease, allowing retrospective coding of large datasets. Coding of ambulance data using ICD-10-AM allows for comparison of not only ambulance service users but also with other population groups. WHAT IS KNOWN ABOUT THE TOPIC? There is no reliable and standard coding and categorising system for paramedic assessment data contained in ambulance service databases. WHAT DOES THIS PAPER ADD? This study demonstrates that ambulance paramedic assessment data can be aligned with ICD-10-AM and MDC with relative ease, allowing retrospective coding of large datasets. Representation of ambulance case types using ICD-10-AM-coded information obtained after paramedic assessment is more fine grained and clinically relevant than point-of-call data, which uses caller information before ambulance attendance. WHAT ARE THE IMPLICATIONS FOR PRACTITIONERS? This paper describes a model of coding using an internationally recognised standard coding and categorising system to support analysis of paramedic assessment. Ambulance data coded using ICD-10-AM allows for reliable reporting and comparison within the prehospital setting and across the healthcare industry.
Reyes-Núñez, Virginia; Galo-Hooker, Evelyn; Pérez-Romano, Beatriz; Duque, Ricardo E; Ruiz-Arguelles, Alejandro; Garcés-Eisele, Javier
2018-01-01
The aim of this work was to simultaneously use multiplex ligation-dependent probe amplification (MLPA) assay and flow cytometric DNA ploidy analysis (FPA) to detect aneuploidy in patients with newly diagnosed acute leukemia. MLPA assay and propidium iodide FPA were used to test samples from 53 consecutive patients with newly diagnosed acute leukemia referred to our laboratory for immunophenotyping. Results were compared by nonparametric statistics. The combined use of both methods significantly increased the rate of detection of aneuploidy as compared to that obtained by each method alone. The limitations of one method are somehow countervailed by the other and vice versa. MPLA and FPA yield different yet complementary information concerning aneuploidy in acute leukemia. The simultaneous use of both methods might be recommended in the clinical setting. © 2017 International Clinical Cytometry Society. © 2017 International Clinical Cytometry Society.
3rd-generation MW/LWIR sensor engine for advanced tactical systems
NASA Astrophysics Data System (ADS)
King, Donald F.; Graham, Jason S.; Kennedy, Adam M.; Mullins, Richard N.; McQuitty, Jeffrey C.; Radford, William A.; Kostrzewa, Thomas J.; Patten, Elizabeth A.; McEwan, Thomas F.; Vodicka, James G.; Wootan, John J.
2008-04-01
Raytheon has developed a 3rd-Generation FLIR Sensor Engine (3GFSE) for advanced U.S. Army systems. The sensor engine is based around a compact, productized detector-dewar assembly incorporating a 640 x 480 staring dual-band (MW/LWIR) focal plane array (FPA) and a dual-aperture coldshield mechanism. The capability to switch the coldshield aperture and operate at either of two widely-varying f/#s will enable future multi-mode tactical systems to more fully exploit the many operational advantages offered by dual-band FPAs. RVS has previously demonstrated high-performance dual-band MW/LWIR FPAs in 640 x 480 and 1280 x 720 formats with 20 μm pitch. The 3GFSE includes compact electronics that operate the dual-band FPA and variable-aperture mechanism, and perform 14-bit analog-to-digital conversion of the FPA output video. Digital signal processing electronics perform "fixed" two-point non-uniformity correction (NUC) of the video from both bands and optional dynamic scene-based NUC; advanced enhancement processing of the output video is also supported. The dewar-electronics assembly measures approximately 4.75 x 2.25 x 1.75 inches. A compact, high-performance linear cooler and cooler electronics module provide the necessary FPA cooling over a military environmental temperature range. 3GFSE units are currently being assembled and integrated at RVS, with the first units planned for delivery to the US Army.
Evolution of miniature detectors and focal plane arrays for infrared sensors
NASA Astrophysics Data System (ADS)
Watts, Louis A.
1993-06-01
Sensors that are sensitive in the infrared spectral region have been under continuous development since the WW2 era. A quest for the military advantage of 'seeing in the dark' has pushed thermal imaging technology toward high spatial and temporal resolution for night vision equipment, fire control, search track, and seeker 'homing' guidance sensing devices. Similarly, scientific applications have pushed spectral resolution for chemical analysis, remote sensing of earth resources, and astronomical exploration applications. As a result of these developments, focal plane arrays (FPA) are now available with sufficient sensitivity for both high spatial and narrow bandwidth spectral resolution imaging over large fields of view. Such devices combined with emerging opto-electronic developments in integrated FPA data processing techniques can yield miniature sensors capable of imaging reflected sunlight in the near IR and emitted thermal energy in the Mid-wave (MWIR) and longwave (LWIR) IR spectral regions. Robotic space sensors equipped with advanced versions of these FPA's will provide high resolution 'pictures' of their surroundings, perform remote analysis of solid, liquid, and gas matter, or selectively look for 'signatures' of specific objects. Evolutionary trends and projections of future low power micro detector FPA developments for day/night operation or use in adverse viewing conditions are presented in the following test.
Evolution of miniature detectors and focal plane arrays for infrared sensors
NASA Technical Reports Server (NTRS)
Watts, Louis A.
1993-01-01
Sensors that are sensitive in the infrared spectral region have been under continuous development since the WW2 era. A quest for the military advantage of 'seeing in the dark' has pushed thermal imaging technology toward high spatial and temporal resolution for night vision equipment, fire control, search track, and seeker 'homing' guidance sensing devices. Similarly, scientific applications have pushed spectral resolution for chemical analysis, remote sensing of earth resources, and astronomical exploration applications. As a result of these developments, focal plane arrays (FPA) are now available with sufficient sensitivity for both high spatial and narrow bandwidth spectral resolution imaging over large fields of view. Such devices combined with emerging opto-electronic developments in integrated FPA data processing techniques can yield miniature sensors capable of imaging reflected sunlight in the near IR and emitted thermal energy in the Mid-wave (MWIR) and longwave (LWIR) IR spectral regions. Robotic space sensors equipped with advanced versions of these FPA's will provide high resolution 'pictures' of their surroundings, perform remote analysis of solid, liquid, and gas matter, or selectively look for 'signatures' of specific objects. Evolutionary trends and projections of future low power micro detector FPA developments for day/night operation or use in adverse viewing conditions are presented in the following test.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ziemer, B; Hubbard, L; Groves, E
2015-06-15
Purpose: To evaluate a first pass analysis (FPA) technique for CT perfusion measurement in a swine animal and its validation using fractional flow reserve (FFR) as a reference standard. Methods: Swine were placed under anesthesia and relevant physiologic parameters were continuously recorded. Intra-coronary adenosine was administered to induce maximum hyperemia. A pressure wire was advanced distal to the first diagonal branch of the left anterior descending (LAD) artery for FFR measurements and a balloon dilation catheter was inserted over the pressure wire into the proximal LAD to create varying levels of stenosis. Images were acquired with a 320-row wide volumemore » CT scanner. Three main coronary perfusion beds were delineated in the myocardium using arteries extracted from CT angiography images using a minimum energy hypothesis. The integrated density in the perfusion bed was used to calculate perfusion using the FPA technique. The perfusion in the LAD bed over a range of stenosis severity was measured. The measured fractional perfusion was compared to FFR and linear regression was performed. Results: The measured fractional perfusion using the FPA technique (P-FPA) and FFR were related as P-FPA = 1.06FFR – 0.06 (r{sup 2} = 0.86). The perfusion measurements were calculated with only three to five total CT volume scans, which drastically reduces the radiation dose as compared with the existing techniques requiring 15–20 volume scans. Conclusion: The measured perfusion using the first pass analysis technique showed good correlation with FFR measurements as a reference standard. The technique for perfusion measurement can potentially make a substantial reduction in radiation dose as compared with the existing techniques.« less
Liu, Liya; Zhao, Mengli; Liu, Xingxun; Zhong, Kui; Tong, Litao; Zhou, Xianrong; Zhou, Sumei
2016-08-01
The majority of phenolic acids in wheat bran are bound to the cell walls. Hence, a high proportion of phenolic acids cannot be extracted with conventional extraction methods. This study aimed to investigate the efficiency of steam explosion pre-treatment in increasing the extractability of phenolic compounds from wheat bran. Bound phenolic acids (BPA) can be released by steam explosion-assisted extraction. Within the experimental range, soluble free phenolic acids (FPA) and soluble conjugated phenolic acids (CPA) increased gradually with residence time and temperature. After steam explosion at 215 °C for 120 s, the total FPA and CPA reached 6671.8 and 2578.6 µg GAE g(-1) bran, respectively, which was about 39-fold and seven-fold higher than that of the untreated sample. Ferulic acid, the major individual phenolic acids in bran, increased from 55.7 to 586.3 µg g(-1) for FPA, and from 44.9 to 1108.4 µg g(-1) for CPA. The antioxidant properties of FPA and CPA extracts were significantly improved after treated. Correlation analysis indicated that the antioxidant capacity was in close relationship with phenolic content in FPA and CPA. Steam explosion pre-treatment could be effectively used to release of BPA and enhance the antioxidant capacity of wheat bran. © 2015 Society of Chemical Industry. © 2015 Society of Chemical Industry.
Mercury-Cadmium-Telluride Focal Plane Array Performance Under Non-Standard Operating Conditions
NASA Technical Reports Server (NTRS)
Richardson, Brandon S.; Eastwood, Michael L.; Bruce, Carl F.; Green, Robert O.; Coles, J. B.
2011-01-01
This paper highlights a new technique that allows the Teledyne Scientific & Imaging LLC TCM6604A Mercury-Cadmium-Telluride (MCT) Focal Plane Array (FPA) to operate at room temperature. The Teledyne MCT FPA has been a standard in Imaging Spectroscopy since its creation in the 1980's. This FPA has been used in applications ranging from space instruments such as CRISM, M3 and ARTEMIS to airborne instruments such as MaRS and the Next Generation AVIRIS Instruments1. Precise focal plane alignment is always a challenge for such instruments. The current FPA alignment process results in multiple cold cycles requiring week-long durations, thereby increasing the risk and cost of a project. These alignment cycles are necessary because optimal alignment is approached incrementally and can only be measured with the FPA and Optics at standard operating conditions, requiring a cold instrument. Instruments using this FPA are normally cooled to temperatures below 150K for the MCT FPA to properly function. When the FPA is run at higher temperatures the dark current increases saturating the output. This paper covers the prospect of warm MCT FPA operation from a theoretical and experimental perspective. We discuss the empirical models and physical laws that govern MCT material properties and predict the optimal settings that will result in the best MCT PA performance at 300K. Theoretical results are then calculated for the proposed settings. We finally present the images and data obtained using the actual system with the warm MCT FPA settings. The paper concludes by emphasizing the strong positive correlation between the measured values and the theoretical results.
FPA-FTIR Microspectroscopy for Monitoring Chemotherapy Efficacy in Triple-Negative Breast Cancer
NASA Astrophysics Data System (ADS)
Zawlik, Izabela; Kaznowska, Ewa; Cebulski, Jozef; Kolodziej, Magdalena; Depciuch, Joanna; Vongsvivut, Jitraporn; Cholewa, Marian
2016-11-01
Triple-negative breast cancer is the most aggressive breast cancer subtype with limited treatment options and a poor prognosis. Approximately 70% of triple-negative breast cancer patients fail to achieve a pathologic complete response (pCR) after chemotherapy due to the lack of targeted therapies for this subtype. We report here the development of a focal-plane-array Fourier transform infrared (FPA-FTIR) microspectroscopic technique combined with principal component analysis (PCA) for monitoring chemotherapy effects in triple-negative breast cancer patients. The PCA results obtained using the FPA-FTIR spectral data collected from the same patients before and after the chemotherapy revealed discriminatory features that were consistent with the pathologic and clinical responses to chemotherapy, indicating the potential of the technique as a monitoring tool for observing chemotherapy efficacy.
High speed imager test station
Yates, George J.; Albright, Kevin L.; Turko, Bojan T.
1995-01-01
A test station enables the performance of a solid state imager (herein called a focal plane array or FPA) to be determined at high image frame rates. A programmable waveform generator is adapted to generate clock pulses at determinable rates for clock light-induced charges from a FPA. The FPA is mounted on an imager header board for placing the imager in operable proximity to level shifters for receiving the clock pulses and outputting pulses effective to clock charge from the pixels forming the FPA. Each of the clock level shifters is driven by leading and trailing edge portions of the clock pulses to reduce power dissipation in the FPA. Analog circuits receive output charge pulses clocked from the FPA pixels. The analog circuits condition the charge pulses to cancel noise in the pulses and to determine and hold a peak value of the charge for digitizing. A high speed digitizer receives the peak signal value and outputs a digital representation of each one of the charge pulses. A video system then displays an image associated with the digital representation of the output charge pulses clocked from the FPA. In one embodiment, the FPA image is formatted to a standard video format for display on conventional video equipment.
High speed imager test station
Yates, G.J.; Albright, K.L.; Turko, B.T.
1995-11-14
A test station enables the performance of a solid state imager (herein called a focal plane array or FPA) to be determined at high image frame rates. A programmable waveform generator is adapted to generate clock pulses at determinable rates for clock light-induced charges from a FPA. The FPA is mounted on an imager header board for placing the imager in operable proximity to level shifters for receiving the clock pulses and outputting pulses effective to clock charge from the pixels forming the FPA. Each of the clock level shifters is driven by leading and trailing edge portions of the clock pulses to reduce power dissipation in the FPA. Analog circuits receive output charge pulses clocked from the FPA pixels. The analog circuits condition the charge pulses to cancel noise in the pulses and to determine and hold a peak value of the charge for digitizing. A high speed digitizer receives the peak signal value and outputs a digital representation of each one of the charge pulses. A video system then displays an image associated with the digital representation of the output charge pulses clocked from the FPA. In one embodiment, the FPA image is formatted to a standard video format for display on conventional video equipment. 12 figs.
Isolation and characterization of a cysteine protease of freesia corms.
Uchikoba, Tetsuya; Okubo, Michiko; Arima, Kazunari; Yonezawa, Hiroo
2002-02-01
A protease, freesia protease (FP)-A, was purified to electrophoretic homogeneity from regular freesia (Freesia reflacta) corms in harvest time. The Mr of FP-A was estimated to be 24 k by SDS-PAGE. The optimum pH of the enzyme was 8.0 using a casein substrate. These enzymes were strongly inhibited by p-chloromercuribenzoic acid but not by phenylmethane-sulfonylfluoride and EDTA. These results indicate that FP-A belongs to the cysteine proteases. The amino terminal sequence of FP-A was similar to that of papain, and the sequences was regarded to the conservative residues of cysteine protease. From the hydrolysis of peptidyl-p-NAs, the specificity of FP-A was found to be broad. It was thought that FP-A was a new protease from freesia corms.
Hara, Naomi; Nishimura, Yukika; Yokoyama, Chika; Inoue, Ken; Nishida, Atsushi; Tanii, Hisashi; Okada, Motohiro; Kaiya, Hisanobu; Okazaki, Yuji
2012-04-11
The place where a patient experiences his/her first panic attack (FPA) may be related to their agoraphobia later in life. However, no investigations have been done into the clinical features according to the place where the FPA was experienced. In particular, there is an absence of detailed research examining patients who experienced their FPA at home. In this study, patients were classified by the location of their FPA and the differences in their clinical features were explored (e.g., symptoms of FPA, frequency of agoraphobia, and severity of FPA). The subjects comprised 830 panic disorder patients who were classified into 5 groups based on the place of their FPA (home, school/office, driving a car, in a public transportation vehicle, outside of home), The clinical features of these patients were investigated. Additionally, for panic disorder patients with agoraphobia at their initial clinic visit, the clinical features of patients who experienced their FPA at home were compared to those who experienced their attack elsewhere. In comparison of the FPAs of the 5 groups, significant differences were seen among the 7 descriptors (sex ratio, drinking status, smoking status, severity of the panic attack, depression score, ratio of agoraphobia, and degree of avoidance behavior) and 4 symptoms (sweating, chest pain, feeling dizzy, and fear of dying). The driving and public transportation group patients showed a higher incidence of co-morbid agoraphobia than did the other groups. Additionally, for panic disorder patients with co-morbid agoraphobia, the at-home group had a higher frequency of fear of dying compared to the patients in the outside-of-home group and felt more severe distress elicited by their FPA. The results of this study suggest that the clinical features of panic disorder patients vary according to the place of their FPA. The at-home group patients experienced "fear of dying" more frequently and felt more distress during their FPA than did the subjects in the other groups. These results indicate that patients experiencing their FPA at home should be treated with a focus on the fear and distress elicited by the attack.
2012-01-01
Background The place where a patient experiences his/her first panic attack (FPA) may be related to their agoraphobia later in life. However, no investigations have been done into the clinical features according to the place where the FPA was experienced. In particular, there is an absence of detailed research examining patients who experienced their FPA at home. In this study, patients were classified by the location of their FPA and the differences in their clinical features were explored (e.g., symptoms of FPA, frequency of agoraphobia, and severity of FPA). Methods The subjects comprised 830 panic disorder patients who were classified into 5 groups based on the place of their FPA (home, school/office, driving a car, in a public transportation vehicle, outside of home), The clinical features of these patients were investigated. Additionally, for panic disorder patients with agoraphobia at their initial clinic visit, the clinical features of patients who experienced their FPA at home were compared to those who experienced their attack elsewhere. Results In comparison of the FPAs of the 5 groups, significant differences were seen among the 7 descriptors (sex ratio, drinking status, smoking status, severity of the panic attack, depression score, ratio of agoraphobia, and degree of avoidance behavior) and 4 symptoms (sweating, chest pain, feeling dizzy, and fear of dying). The driving and public transportation group patients showed a higher incidence of co-morbid agoraphobia than did the other groups. Additionally, for panic disorder patients with co-morbid agoraphobia, the at-home group had a higher frequency of fear of dying compared to the patients in the outside-of-home group and felt more severe distress elicited by their FPA. Conclusion The results of this study suggest that the clinical features of panic disorder patients vary according to the place of their FPA. The at-home group patients experienced "fear of dying" more frequently and felt more distress during their FPA than did the subjects in the other groups. These results indicate that patients experiencing their FPA at home should be treated with a focus on the fear and distress elicited by the attack. PMID:22494552
Forward Period Analysis Method of the Periodic Hamiltonian System.
Wang, Pengfei
2016-01-01
Using the forward period analysis (FPA), we obtain the period of a Morse oscillator and mathematical pendulum system, with the accuracy of 100 significant digits. From these results, the long-term [0, 1060] (time unit) solutions, ranging from the Planck time to the age of the universe, are computed reliably and quickly with a parallel multiple-precision Taylor series (PMT) scheme. The application of FPA to periodic systems can greatly reduce the computation time of long-term reliable simulations. This scheme provides an efficient way to generate reference solutions, against which long-term simulations using other schemes can be tested.
Precise annealing of focal plane arrays for optical detection
Bender, Daniel A.
2015-09-22
Precise annealing of identified defective regions of a Focal Plane Array ("FPA") (e.g., exclusive of non-defective regions of the FPA) facilitates removal of defects from an FPA that has been hybridized and/or packaged with readout electronics. Radiation is optionally applied under operating conditions, such as under cryogenic temperatures, such that performance of an FPA can be evaluated before, during, and after annealing without requiring thermal cycling.
Precise annealing of focal plane arrays for optical detection
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bender, Daniel A.
2017-10-17
Precise annealing of identified defective regions of a Focal Plane Array ("FPA") (e.g., exclusive of non-defective regions of the FPA) facilitates removal of defects from an FPA that has been hybridized and/or packaged with readout electronics. Radiation is optionally applied under operating conditions, such as under cryogenic temperatures, such that performance of an FPA can be evaluated before, during, and after annealing without requiring thermal cycling.
Implementation of a noise reduction circuit for spaceflight IR spectrometers
NASA Technical Reports Server (NTRS)
Ramirez, L.; Hickok, R.; Pain, B.; Staller, C.
1992-01-01
The paper discusses the implementation and analysis of a correlated triple sampling circuit using analog subtractor/integrators. The software and test setup for noise measurements are also described. The correlation circuitry is part of the signal chain for a 256-element InSb line array used in the Visible and Infrared Mapping Spectrometer. Using a focal-plane array (FPA) simulator, system noise measurements of 0.7 DN are obtained. A test setup for FPA/SPE (signal processing electronics) characterization along with noise measurements is demonstrated.
Xu, Zhengming; Han, Dexia; Li, Yuan; Zhang, Pingling; You, Lijun; Zhao, Zhengang
2018-04-23
In this study, the FPA90-Cl resin was magnetized with supported Fe 3 O 4 particles using a chemical co-precipitation method and its removal performance of bromate and coexisting precursors was explored. The magnetized FPA90-Cl resin was structurally characterized by SEM, FT-IR, and XRD. The effects of the initial concentrations, temperature, and resin dosage on bromate and bromide ion removal in drinking water were investigated using batch experiments. The magnetized FPA90-Cl resin exhibited a high removal efficiency for bromate and bromide ions at three initial concentrations, and the residual bromate concentrations were under the maximum contaminant level (MCL) of 10 μg L -1 after 80 min. The adsorption data of bromate and bromide ion could be well described by a pseudo-first-order kinetic model (R 2 ˃ 0.98). The bromate removal alone was further studied by varying the initial solution pH, temperature, and competitive anions. The results showed that the magnetized FPA90-Cl resin could be used over a wide pH range (4.0-9.0). The maximum sorption capacity of the magnetized FPA90-Cl resin for bromate reached 132.83 mg g -1 at 298 K. The Freundlich and Redlich-Peterson isotherm models fit the bromate adsorption equilibrium better (R 2 ˃ 0.99) than the Langmuir isotherm model (R 2 ˃ 0.98). The thermodynamic analysis showed that the bromate adsorption process was endothermic. The negative ΔG and positive ΔS indicated that the process was spontaneous and that randomness increased after adsorption, respectively. The competition of coexisting anions with bromate was in the order of SO 4 2- > CO 3 2- > Cl - > NO 3 - > HCO 3 - > PO 4 3- . Additionally, the magnetized FPA90-Cl resin could maintain a high bromate and bromide ion adsorption capacity after five cycles of regeneration by a 0.1 M NaCl solution. Graphical abstract ᅟ.
Mayer, Bernhard X; Mensik, Christa; Krishnaswami, Sriram; Derendorf, Hartmut; Eichler, Hans-Georg; Schmetterer, Leopold; Wolzt, Michael
1999-01-01
Aims It has been demonstrated that inhibition of endothelium derived nitric oxide with NG-monomethyl-l-arginine (l-NMMA) results in a different cardiac and peripheral vascular response. The purpose of this study was to investigate the pharmacokinetic-pharmacodynamic profile of l-NMMA and pharmacokinetic interactions with l-arginine in healthy subjects. Methods Plasma pharmacokinetics were analysed from two different studies: In study 1, 3 mg kg−1 l-NMMA was administered i.v. over 5 min and systemic haemodynamics, cardiac output (CO), fundus pulsation amplitude (FPA), and NO-exhalation (exhNO) were measured at baseline and 15, 65, 95, 155, and 305 min after start of drug administration (n=7). In study 2, 17 mg kg−1 min−1 of the physiologic substrate for nitric oxide synthase, l-arginine, was coinfused i.v. over 30 min with a primed constant infusion of 50 μg kg−1 min−1 l-NMMA (n=8). Results Bolus infusion of l-NMMA resulted in a maximum plasma concentration of 12.9±3.4 μg ml−1 (mean±s.d.) with elimination half-life of 63.5±14.5 min and clearance of 12.2±3.5 ml min−1 kg−1 and caused a small hypertensive response, decreased CO by 13%, FPA by 26%, exhNO by 46% and increased systemic vascular resistance by 16% (P<0.05 each) 15 min after start of drug administration. Although only limited data points were available in the l-NMMA plasma concentration range between 0 and 4 μg ml−1, drug effects over time were in good agreement with an Emax model (r2>0.98 each), which also suggested that concentrations producing half-maximum effects were higher for FPA than for CO and exhNO. The coinfusion with l-arginine caused a nearly two-fold increase in plasma l-NMMA levels, indicating a pharmacokinetic interaction. Conclusions In the absence of a systemic hypertensive response, l-NMMA significantly decreased CO, exhNO, and FPA. The concentration calculated to produce a half maximal effect was equivalent for exhNO and CO, but markedly higher for FPA. Furthermore, measurement of FPA is susceptible to changes in l-NMMA levels at small plasma concentrations. PMID:10336578
Gillard, Frédéric; Ferrec, Yann; Guérineau, Nicolas; Rommeluère, Sylvain; Taboury, Jean; Chavel, Pierre
2012-06-01
Stationary Fourier transform spectrometry is an interesting concept for building reliable field or embedded spectroradiometers, especially for the mid- and far- IR. Here, a very compact configuration of a cryogenic stationary Fourier transform IR (FTIR) spectrometer is investigated, where the interferometer is directly integrated in the focal plane array (FPA). We present a theoretical analysis to explain and describe the fringe formation inside the FTIR-FPA structure when illuminated by an extended source positioned at a finite distance from the detection plane. The results are then exploited to propose a simple front lens design compatible with a handheld package.
Novel Heterongineered Detectors for Multi-Color Infrared Sensing
2012-01-30
barriers”. Appl. Phys. Lett. 98, 121106 (2011) 9. A. Khoshakhlagh, F. Jaeckel C. Hains J. B. Rodriguez , L. R. Dawson, K. Malloy, and S. Krishna...AlAs etch-stop layer. The detailed processing sequence is included in the Methods. b da c n + -GaAs 200 nm Mesa lndium bump 2.1 –2.1 FPA p d SP-FPA...FPA chip. The processing scheme of the plasmonic FPA chip consists of a dry etch to form the mesa , surface passivation, ohmic metal evaporation, under
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hubbard, L; Ziemer, B; Lipinski, J
Purpose: To evaluate the accuracy of a low-dose, first-pass-analysis (FPA) dynamic computed tomography angiography and perfusion (CTAP) technique, for whole-organ anatomical and functional assessment of coronary artery disease (CAD). Methods: An angioplasty balloon was advanced into the left anterior descending (LAD) coronary artery of five swine (35–45 kg) to induce several levels of stenosis at maximal hyperemia (intracoronary adenosine, 240 µg/min). Reference fluorescence microspheres and intravenous contrast (370 mg/mL iodine, 25 mL, 7 mL/s) were injected centrally and dynamic imaging was performed using a 320-slice CT scanner at 100 kVp and 200 mA. Twenty volume scans were acquired per stenosismore » level to capture complete aortic and myocardial enhancement curves, but only two volume scans were used for whole-organ dynamic FPA CTAP measurement. All CTAP measurements in the LAD were compared to the reference microsphere perfusion measurements using linear regression, concordance correlation, and Bland-Altman analysis. Results: The result of dynamic FPA CTAP measurement in the LAD was in good agreement with the reference microsphere perfusion measurement (P-CTAP = 1.01 P-MICRO + 0.16, R{sup 2} = 0.95). The root mean square error (RMSE) and difference (RMSD) of measurement were 0.51 mL/min/g and 0.47 mL/min/g, respectively. Bland-Altman analysis demonstrated negligible systematic measurement bias. Additionally, the concordance correlation coefficient (CCC) was found to be ρ = 0.97, indicating excellent agreement between dynamic FPA CTAP measurement and the reference microsphere perfusion measurement. Lastly, the effective dose of the proposed technique using the “simulated” two-volume scan CTAP acquisition protocol was 2.6 mSv; much lower than the ∼10 mSv effective dose of current dynamic CTP techniques alone. Conclusion: The results indicate the potential for significant improvements in CAD assessment through low-dose, quantitative dynamic FPA CTAP. Such improvements are afforded through whole-organ CT scanning technology, and have the potential to improve patient outcomes and lead to healthier patient lives. Conflict of Interest (only if applicable): Grant funding from Toshiba America Medical Systems.« less
Chapinal, Núria; Schumaker, Brant A; Joly, Damien O; Elkin, Brett T; Stephen, Craig
2015-07-01
We estimated the sensitivity and specificity of the caudal-fold skin test (CFT), the fluorescent polarization assay (FPA), and the rapid lateral-flow test (RT) for the detection of Mycobacterium bovis in free-ranging wild wood bison (Bison bison athabascae), in the absence of a gold standard, by using Bayesian analysis, and then used those estimates to forecast the performance of a pairwise combination of tests in parallel. In 1998-99, 212 wood bison from Wood Buffalo National Park (Canada) were tested for M. bovis infection using CFT and two serologic tests (FPA and RT). The sensitivity and specificity of each test were estimated using a three-test, one-population, Bayesian model allowing for conditional dependence between FPA and RT. The sensitivity and specificity of the combination of CFT and each serologic test in parallel were calculated assuming conditional independence. The test performance estimates were influenced by the prior values chosen. However, the rank of tests and combinations of tests based on those estimates remained constant. The CFT was the most sensitive test and the FPA was the least sensitive, whereas RT was the most specific test and CFT was the least specific. In conclusion, given the fact that gold standards for the detection of M. bovis are imperfect and difficult to obtain in the field, Bayesian analysis holds promise as a tool to rank tests and combinations of tests based on their performance. Combining a skin test with an animal-side serologic test, such as RT, increases sensitivity in the detection of M. bovis and is a good approach to enhance disease eradication or control in wild bison.
A spatial database of wildfires in the United States, 1992-2011
NASA Astrophysics Data System (ADS)
Short, K. C.
2013-07-01
The statistical analysis of wildfire activity is a critical component of national wildfire planning, operations, and research in the United States (US). However, there are multiple federal, state, and local entities with wildfire protection and reporting responsibilities in the US, and no single, unified system of wildfire record-keeping exists. To conduct even the most rudimentary interagency analyses of wildfire numbers and area burned from the authoritative systems of record, one must harvest records from dozens of disparate databases with inconsistent information content. The onus is then on the user to check for and purge redundant records of the same fire (i.e. multijurisdictional incidents with responses reported by several agencies or departments) after pooling data from different sources. Here we describe our efforts to acquire, standardize, error-check, compile, scrub, and evaluate the completeness of US federal, state, and local wildfire records from 1992-2011 for the national, interagency Fire Program Analysis (FPA) application. The resulting FPA Fire-occurrence Database (FPA FOD) includes nearly 1.6 million records from the 20 yr period, with values for at least the following core data elements: location at least as precise as a Public Land Survey System section (2.6 km2 grid), discovery date, and final fire size. The FPA FOD is publicly available from the Research Data Archive of the US Department of Agriculture, Forest Service (doi:10.2737/RDS-2013-0009). While necessarily incomplete in some aspects, the database is intended to facilitate fairly high-resolution geospatial analysis of US wildfire activity over the past two decades, based on available information from the authoritative systems of record.
A spatial database of wildfires in the United States, 1992-2011
NASA Astrophysics Data System (ADS)
Short, K. C.
2014-01-01
The statistical analysis of wildfire activity is a critical component of national wildfire planning, operations, and research in the United States (US). However, there are multiple federal, state, and local entities with wildfire protection and reporting responsibilities in the US, and no single, unified system of wildfire record keeping exists. To conduct even the most rudimentary interagency analyses of wildfire numbers and area burned from the authoritative systems of record, one must harvest records from dozens of disparate databases with inconsistent information content. The onus is then on the user to check for and purge redundant records of the same fire (i.e., multijurisdictional incidents with responses reported by several agencies or departments) after pooling data from different sources. Here we describe our efforts to acquire, standardize, error-check, compile, scrub, and evaluate the completeness of US federal, state, and local wildfire records from 1992-2011 for the national, interagency Fire Program Analysis (FPA) application. The resulting FPA Fire-Occurrence Database (FPA FOD) includes nearly 1.6 million records from the 20 yr period, with values for at least the following core data elements: location, at least as precise as a Public Land Survey System section (2.6 km2 grid), discovery date, and final fire size. The FPA FOD is publicly available from the Research Data Archive of the US Department of Agriculture, Forest Service (doi:10.2737/RDS-2013-0009). While necessarily incomplete in some aspects, the database is intended to facilitate fairly high-resolution geospatial analysis of US wildfire activity over the past two decades, based on available information from the authoritative systems of record.
NASA Astrophysics Data System (ADS)
Kastek, Mariusz; PiÄ tkowski, Tadeusz; Polakowski, Henryk; Barela, Jaroslaw; Firmanty, Krzysztof; Trzaskawka, Piotr; Vergara, German; Linares, Rodrigo; Gutierrez, Raul; Fernandez, Carlos; Montojo Supervielle, Maria Teresa
2014-05-01
The paper presents some aspects of muzzle flash detection using low resolution polycrystalline PbSe 32×32 and 80×80 detectors FPA operating at room temperature (uncooled performance). These sensors, which detect in MWIR (3 - 5 microns region) and are manufactured using proprietary technology from New Infrared Technologies (VPD PbSe - Vapor Phase Deposition of polycrystalline PbSe), can be applied to muzzle flash detection. The system based in the uncooled 80×80 FPA monolithically integrated with the CMOS readout circuitry has allowed image recording with frame rates over 2000 Hz (true snapshot acquisition), whereas the lower density, uncooled 32×32 FPA is suitable for being used in low cost infrared imagers sensitive in the MWIR band with frame rates above 1000 Hz. The FPA detector, read-out electronics and processing electronics (allows the implementation of some algorithms for muzzle flash detection) of both systems are presented. The systems have been tested at field test ground. Results of detection range measurement with two types of optical systems (wide and narrow field of view) have been shown. The theoretical analysis of possibility detection of muzzle flash and initial results of testing of some algorithms for muzzle flash detection have been presented too.
Mancini-Filho, Jorge; Novoa, Alexis Vidal; González, Ana Elsa Batista; de Andrade-Wartha, Elma Regina S; de O e Silva, Ana Mara; Pinto, José Ricardo; Mancini, Dalva Assunção Portari
2009-01-01
Phenolic compounds are found in seaweed species together with other substances presenting antioxidant activity. The objective of this work was to evaluate the antioxidant activity of the free phenolic acids (FPA) fraction from the seaweed Halimeda monile, and its activity to protect the expression of hepatic enzymes in rats, under experimental CCl4 injury. The antioxidant activity was measured by the DPPH method. The FPA fraction (80 mg/kg, p.o.) was administered during 20 consecutive days to rats. The peroxidation was performed by thiobarbituric acid reactive substances (TBARS). The SOD and CAT enzymatic expressions were measured by RT/PCR. The histology technique was used to evaluate liver injuries. The expression of both, CAT and SOD genes, was more preserved by FPA. Only partial injury could be observed by histology in the liver of rats receiving FPA as compared with the control group; and CCl4 administration induced 60% more peroxidation as compared with the rats receiving FPA. These data suggest that FPA could modulate the antioxidant enzymes and oxidative status in the liver through protection against adverse effects induced by chemical agents.
Forward Propagation Analysis for determining the 16O(n,α)13C Reaction Cross Section at LANSCE
NASA Astrophysics Data System (ADS)
Purcell, Zachary; Lee, Hye Young; Davison, Jacob
2017-09-01
Oxygen is present in many materials and the uncertainties in its nuclear data can have a significant impact on applications. In particular, neutron-absorption reactions reduceavailable neutrons in applications. Thus,high precision in knowledge of this reaction cross sectionis required. To decreasethe systematic uncertainty, we developed a framework that uses Forward Propagation Analysis (FPA) for determining the 16O(n,α)13C reaction cross section from data measured at LANSCE. The Low Energy NZ (LENZ) instrument was used to detectreaction alphas on the Ta2 O5 solid target with silicon strip detectors. The FPA was performed in GEANT4. The geometry, efficiency, and resolution functions of LENZ werevalidated by comparing with the alpha emitting Th-229 source measurement. To reproduce experimental yields in silicon strip detectors, the energy dependent neutron beam flux distribution, the 16O(n,a) reaction differential cross sections, and the 2-body kinematics calculations were implemented in the simulation. We present results from the FPA on LENZ data anddiscuss the improved data analysis [LA-UR-17-26436]. This work has benefited from the use of the Los Alamos Neutron Science Center, is funded by the US Department of Energy and operated by Los Alamos National Security, LLC under Contract DE-AC52-06NA25396.
Dual-band QWIP MWIR/LWIR focal plane array test results
NASA Astrophysics Data System (ADS)
Goldberg, Arnold C.; Fischer, Theodore; Kennerly, Stephen; Wang, Samuel C.; Sundaram, Mani; Uppal, Parvez; Winn, Michael L.; Milne, Gregory L.; Stevens, Mark A.
2000-07-01
We report on the results of laboratory and field tests on a pixel-registered, 2-color MWIR/LWIR 256 X 256 QWIP FPA with simultaneous integrating capability. The FPA studied contained stacked QWIP structures with spectral peaks at 5.1 micrometer and 9.0 micrometer. Normally incident radiation was coupled into the devices using a diffraction grating designed to operate in both spectral bands. Each pixel is connected to the read-out integrated circuit by three bumps to permit the application of separate bias levels to each QWIP stack and allow simultaneous integration of the signal current in each band. We found the FPA to have high pixel operability, well balanced response, good imaging performance, high optical fill factor, and low spectral crosstalk. We present data on measurements of the noise-equivalent temperature difference of the FPA in both bands as functions of temperature and bias. The FPA data are compared to single-pixel data taken on devices from the same wafer. We also present data on the sensitivity of this FPA to polarized light. It is found that the LWIR portion of the device is very sensitive to the direction of polarization of the incident light. The MWIR part of the device is relatively insensitive to the polarization. In addition, imagery was taken with this FPA of military targets in the field. Image fusion techniques were applied to the resulting images.
The STAR-X X-Ray Telescope Assembly (XTA)
NASA Technical Reports Server (NTRS)
McClelland, Ryan S.; Bautz, Mark W.; Bonafede, Joseph A.; Miller, Eric D.; Saha, Timo T.; Solly, Peter M.; Zhang, William W.
2017-01-01
The Survey and Time-domain Astrophysical Research eXplorer (STAR-X) science goals are to discover what powers the most violent explosions in the Universe, understand how black holes grow across cosmic time and mass scale, and measure how structure formation heats the majority of baryons in the Universe. To achieve these goals, STAR-X requires a powerful X-ray telescope with a large field of view, large collecting area, and excellent point spread function. The STAR-X instrument, the X-Ray Telescope Assembly (XTA), meets these requirements using a powerful X-ray mirror technology based on precision-polished single crystal silicon and a mature CCD detector technology. The XTA is composed of three major subsystems: an X-ray Mirror Assembly (MA) of high resolution, lightweight mirror segments fabricated out of single crystal silicon; a Focal Plane Assembly (FPA) made of back-illuminated CCD's capable of detecting X-rays with excellent quantum efficiency; and a composite Telescope Tube that structurally links the MA and FPA. The MA consists of 5,972 silicon mirror segments mounted into five subassemblies called meta-shells. A meta-shell is constructed from an annular central structural shell covered with interlocking layers of mirror segments. This paper describes the requirements, design, and analysis of the XTA subsystems with particular focus on the MA.
The STAR-X X-Ray Telescope Assembly (XTA)
NASA Astrophysics Data System (ADS)
McClelland, Ryan S.
2017-08-01
The Survey and Time-domain Astrophysical Research eXplorer (STAR-X) science goals are to discover what powers the most violent explosions in the Universe, understand how black holes grow across cosmic time and mass scale, and measure how structure formation heats the majority of baryons in the Universe. To achieve these goals, STAR-X requires a powerful X-ray telescope with a large field of view, large collecting area, and excellent point spread function. The STAR-X instrument, the X-Ray Telescope Assembly (XTA), meets these requirements using a powerful X-ray mirror technology based on precision-polished single crystal silicon and a mature CCD detector technology. The XTA is composed of three major subsystems: an X-ray Mirror Assembly (MA) of high resolution, lightweight mirror segments fabricated out of single crystal silicon; a Focal Plane Assembly (FPA) made of back-illuminated CCDs capable of detecting X-rays with excellent quantum efficiency; and a composite Telescope Tube that structurally links the MA and FPA. The MA consists of 5,972 silicon mirror segments mounted into five subassemblies called metashells. A meta-shell is constructed from an annular central structural shell covered with interlocking layers of mirror segments. This paper describes the requirements, design, and analysis of the XTA subsystems with particular focus on the MA.
Cossey, D
1993-01-01
In the UK, the Chairwoman of the Family Planning Association (FPA) praises the staff and volunteers with whom she has worked for their incessant inability to meet the many challenges they face. During her 6 years, however, the FPA had to reduce the number of regional offices and staff. It did not need to reduce salaries, however. FPA membership directly elects the National Executive Council which is now smaller. FPA is exploring new sources of funding and is adapting to the purchaser/provider relationship in the statutory sector, resulting in its successful financial strategy. The Department of Health helps in maintaining FPA's ability to continue to operate. The Chairwoman sees indications of needing to fight old battles again, e.g., some officials have suggested limiting the range of oral contraceptives available from prescription by the National Health Services (NHS) which would be the end of almost 20 years of free contraception and free choice under the NHS. The government is not open to including sex education the school curriculum. The NHS gives the impression in its report "The Health of the Nation" that it is committed to reducing adolescent pregnancies among the youngest teenagers and to recognizing the importance of good policies on sexual health. Yet, its actions exhibit no compassion for single parents. Participants at FPA's 1992 conference agree that variety, quality, and sensitivity of family planning provisions are needed and that family planning clinics and general practitioners should work together. FPA has contributed to the UK the clinic network; the concept of family planning being an integral part of a comprehensive health service; and the notion that family planning includes contraception, empowerment of women, sexual health, rights, and responsibilities. FPA should reaffirm these ideas and secure the future for informed choice and planned pregnancy.
Hybrid flower pollination algorithm strategies for t-way test suite generation.
Nasser, Abdullah B; Zamli, Kamal Z; Alsewari, AbdulRahman A; Ahmed, Bestoun S
2018-01-01
The application of meta-heuristic algorithms for t-way testing has recently become prevalent. Consequently, many useful meta-heuristic algorithms have been developed on the basis of the implementation of t-way strategies (where t indicates the interaction strength). Mixed results have been reported in the literature to highlight the fact that no single strategy appears to be superior compared with other configurations. The hybridization of two or more algorithms can enhance the overall search capabilities, that is, by compensating the limitation of one algorithm with the strength of others. Thus, hybrid variants of the flower pollination algorithm (FPA) are proposed in the current work. Four hybrid variants of FPA are considered by combining FPA with other algorithmic components. The experimental results demonstrate that FPA hybrids overcome the problems of slow convergence in the original FPA and offers statistically superior performance compared with existing t-way strategies in terms of test suite size.
Hybrid flower pollination algorithm strategies for t-way test suite generation
Zamli, Kamal Z.; Alsewari, AbdulRahman A.
2018-01-01
The application of meta-heuristic algorithms for t-way testing has recently become prevalent. Consequently, many useful meta-heuristic algorithms have been developed on the basis of the implementation of t-way strategies (where t indicates the interaction strength). Mixed results have been reported in the literature to highlight the fact that no single strategy appears to be superior compared with other configurations. The hybridization of two or more algorithms can enhance the overall search capabilities, that is, by compensating the limitation of one algorithm with the strength of others. Thus, hybrid variants of the flower pollination algorithm (FPA) are proposed in the current work. Four hybrid variants of FPA are considered by combining FPA with other algorithmic components. The experimental results demonstrate that FPA hybrids overcome the problems of slow convergence in the original FPA and offers statistically superior performance compared with existing t-way strategies in terms of test suite size. PMID:29718918
Linear antenna array optimization using flower pollination algorithm.
Saxena, Prerna; Kothari, Ashwin
2016-01-01
Flower pollination algorithm (FPA) is a new nature-inspired evolutionary algorithm used to solve multi-objective optimization problems. The aim of this paper is to introduce FPA to the electromagnetics and antenna community for the optimization of linear antenna arrays. FPA is applied for the first time to linear array so as to obtain optimized antenna positions in order to achieve an array pattern with minimum side lobe level along with placement of deep nulls in desired directions. Various design examples are presented that illustrate the use of FPA for linear antenna array optimization, and subsequently the results are validated by benchmarking along with results obtained using other state-of-the-art, nature-inspired evolutionary algorithms such as particle swarm optimization, ant colony optimization and cat swarm optimization. The results suggest that in most cases, FPA outperforms the other evolutionary algorithms and at times it yields a similar performance.
NASA Technical Reports Server (NTRS)
Muniz, R.; Martinez, El; Szafran, J.; Dalton, A.
2011-01-01
The Function Point Analysis (FPA) Depot is a web application originally designed by one of the NE-C3 branch's engineers, Jamie Szafran, and created specifically for the Software Development team of the Launch Control Systems (LCS) project. The application consists of evaluating the work of each developer to be able to get a real estimate of the hours that is going to be assigned to a specific task of development. The Architect Team had made design change requests for the depot to change the schema of the application's information; that information, changed in the database, needed to be changed in the graphical user interface (GUI) (written in Ruby on Rails (RoR and the web service/server side in Java to match the database changes. These changes were made by two interns from NE-C, Ricardo Muniz from NE-C3, who made all the schema changes for the GUI in RoR and Edwin Martinez, from NE-C2, who made all the changes in the Java side.
NASA Technical Reports Server (NTRS)
Gunapala, S. D.; Bandara, S. V.
2004-01-01
A 640x512 pixel, long-wavelength cutoff, narrow-band (delta(lambda)/approx. 10%) quantum well infrared photodetector (QWIP) focal plane array (FPA), a four-band QWIP FPA in the 4-16 m spectral region, and a broad-band (delta(lambda)/approx. 42%) QWIP FPA having 15.4 m cutoff have been demonstrated.
French, Rebecca S; Cowan, Frances M; Wellings, Kaye; Dowie, Jack
2014-04-01
My Contraception Tool (MCT) applies the principles of multi-criteria decision analysis to the choice of contraceptive method. Its purpose is to make the decision-making process transparent to the user and to suggest a method to them based on their own preferences. The contraceptive option that emerges as optimal from the analysis takes account of the probability of a range of outcomes and the relative weight ascribed to them by the user. The development of MCT was a collaborative project between London School of Hygiene & Tropical Medicine, Brook, FPA and Maldaba Ltd. MCT is available online via the Brook and FPA websites. In this article we describe MCT's development and how it works. Further work is needed to assess the impact it has on decision quality and contraceptive behaviour.
Microplate-based filter paper assay to measure total cellulase activity.
Xiao, Zhizhuang; Storms, Reginald; Tsang, Adrian
2004-12-30
The standard filter paper assay (FPA) published by the International Union of Pure and Applied Chemistry (IUPAC) is widely used to determine total cellulase activity. However, the IUPAC method is not suitable for the parallel analyses of large sample numbers. We describe here a microplate-based method for assaying large sample numbers. To achieve this, we reduced the enzymatic reaction volume to 60 microl from the 1.5 ml used in the IUPAC method. The modified 60-microl format FPA can be carried out in 96-well assay plates. Statistical analyses showed that the cellulase activities of commercial cellulases from Trichoderma reesei and Aspergillus species determined with our 60-microl format FPA were not significantly different from the activities measured with the standard FPA. Our results also indicate that the 60-microl format FPA is quantitative and highly reproducible. Moreover, the addition of excess beta-glucosidase increased the sensitivity of the assay by up to 60%. 2004 Wiley Periodicals, Inc.
High-Performance LWIR Superlattice Detectors and FPA Based on CBIRD Design
NASA Technical Reports Server (NTRS)
Soibel, Alexander; Nguyen, Jean; Khoshakhlagh, Arezou; Rafol, Sir B.; Hoeglund, Linda; Keo, Sam A.; Mumolo, Jason M.; Liu, John; Liao, Anna; Ting, David Z.-Y.;
2012-01-01
We report our recent efforts on advancing of antimonide superlattice based infrared photodetectors and demonstration of Focal Plane Arrays (FPA) based on a complementary barrier infrared detector (CBIRD) design. By optimizing design and growth condition we succeeded to reduce the operational bias of CBIRD single pixel detector without increase of dark current or degradation of quantum efficiency. We demonstrated a 1024x1024 pixel long-wavelength infrared focal plane array utilizing CBIRD design. An 11.5 ?m cutoff FPA without anti-reflection coating has yielded noise equivalent differential temperature of 53 mK at operating temperature of 80 K, with 300 K background and cold-stop. In addition, we demonstrated 320x256 format FPA based on the n-CBIRD design. The resulting FPAs yielded noise equivalent differential temperature of 26 mK at operating temperature of 80 K, with 300 K background and cold-stop. These results advance state-of-the art of superlattice detectors and demonstrated advantages of CBIRD architecture for realization of FPA.
Development of Thermal Infrared Sensor to Supplement Operational Land Imager
NASA Technical Reports Server (NTRS)
Shu, Peter; Waczynski, Augustyn; Kan, Emily; Wen, Yiting; Rosenberry, Robert
2012-01-01
The thermal infrared sensor (TIRS) is a quantum well infrared photodetector (QWIP)-based instrument intended to supplement the Operational Land Imager (OLI) for the Landsat Data Continuity Mission (LDCM). The TIRS instrument is a far-infrared imager operating in the pushbroom mode with two IR channels: 10.8 and 12 m. The focal plane will contain three 640 512 QWIP arrays mounted onto a silicon substrate. The readout integrated circuit (ROIC) addresses each pixel on the QWIP arrays and reads out the pixel value (signal). The ROIC is controlled by the focal plane electronics (FPE) by means of clock signals and bias voltage value. The means of how the FPE is designed to control and interact with the TIRS focal plane assembly (FPA) is the basis for this work. The technology developed under the FPE is for the TIRS focal plane assembly (FPA). The FPE must interact with the FPA to command and control the FPA, extract analog signals from the FPA, and then convert the analog signals to digital format and send them via a serial link (USB) to a computer. The FPE accomplishes the described functions by converting electrical power from generic power supplies to the required bias power that is needed by the FPA. The FPE also generates digital clocking signals and shifts the typical transistor-to-transistor logic (TTL) to }5 V required by the FPA. The FPE also uses an application- specific integrated circuit (ASIC) named System Image, Digitizing, Enhancing, Controlling, And Retrieving (SIDECAR) from Teledyne Corp. to generate the clocking patterns commanded by the user. The uniqueness of the FPE for TIRS lies in that the TIRS FPA has three QWIP detector arrays, and all three detector arrays must be in synchronization while in operation. This is to avoid data skewing while observing Earth flying in space. The observing scenario may be customized by uploading new control software to the SIDECAR.
Li, Weide; Kong, Demeng; Wu, Jinran
2017-01-01
Air pollution in China is becoming more serious especially for the particular matter (PM) because of rapid economic growth and fast expansion of urbanization. To solve the growing environment problems, daily PM2.5 and PM10 concentration data form January 1, 2015, to August 23, 2016, in Kunming and Yuxi (two important cities in Yunnan Province, China) are used to present a new hybrid model CI-FPA-SVM to forecast air PM2.5 and PM10 concentration in this paper. The proposed model involves two parts. Firstly, due to its deficiency to assess the possible correlation between different variables, the cointegration theory is introduced to get the input-output relationship and then obtain the nonlinear dynamical system with support vector machine (SVM), in which the parameters c and g are optimized by flower pollination algorithm (FPA). Six benchmark models, including FPA-SVM, CI-SVM, CI-GA-SVM, CI-PSO-SVM, CI-FPA-NN, and multiple linear regression model, are considered to verify the superiority of the proposed hybrid model. The empirical study results demonstrate that the proposed model CI-FPA-SVM is remarkably superior to all considered benchmark models for its high prediction accuracy, and the application of the model for forecasting can give effective monitoring and management of further air quality.
Wu, Jinran
2017-01-01
Air pollution in China is becoming more serious especially for the particular matter (PM) because of rapid economic growth and fast expansion of urbanization. To solve the growing environment problems, daily PM2.5 and PM10 concentration data form January 1, 2015, to August 23, 2016, in Kunming and Yuxi (two important cities in Yunnan Province, China) are used to present a new hybrid model CI-FPA-SVM to forecast air PM2.5 and PM10 concentration in this paper. The proposed model involves two parts. Firstly, due to its deficiency to assess the possible correlation between different variables, the cointegration theory is introduced to get the input-output relationship and then obtain the nonlinear dynamical system with support vector machine (SVM), in which the parameters c and g are optimized by flower pollination algorithm (FPA). Six benchmark models, including FPA-SVM, CI-SVM, CI-GA-SVM, CI-PSO-SVM, CI-FPA-NN, and multiple linear regression model, are considered to verify the superiority of the proposed hybrid model. The empirical study results demonstrate that the proposed model CI-FPA-SVM is remarkably superior to all considered benchmark models for its high prediction accuracy, and the application of the model for forecasting can give effective monitoring and management of further air quality. PMID:28932237
SABER on Orbit Performance Evaluation and Lessons Learned
NASA Astrophysics Data System (ADS)
Jensen, Scott M.; Batty, J. Clair
2004-06-01
The Sounding of the Atmosphere using Broadband Emission Radiometry (SABER) instrument, launched into orbit December 7, 2001, utilized a miniature pulse-tube cryocooler to maintain the SABER focal plane assembly (FPA) at 75 K. The limited cooling capacity of the cryocooler necessitated the development of a new never before flown Fiber Support Technology (FiST) for supporting and thermally isolating the FPA. A very precise predictive thermal modeling effort to ensure successful operation was also needed due to the very small capacity margin of the cryocooler. A high performance thermal link that minimized the temperature difference between the FPA and the cryocooler cold block and also the mechanical dynamic loading on the fragile pulse tube was developed and space qualified. This paper presents a comparison of the thermal modeling predictions with on orbit measurements, and discusses the lessons learned concerning long term performance issues of thermal isolation systems which utilize cryocoolers for cooling focal plane assemblies (FPA's). The effect of ice deposition on the thermal blankets and other FPA cooled structures, as well as the lessons learned in dealing with this ice deposition, will also be presented.
Limb flexion-induced axial compression and bending in human femoropopliteal artery segments.
Poulson, William; Kamenskiy, Alexey; Seas, Andreas; Deegan, Paul; Lomneth, Carol; MacTaggart, Jason
2018-02-01
High failure rates of femoropopliteal artery (FPA) interventions are often attributed in part to severe mechanical deformations that occur with limb movement. Axial compression and bending of the FPA likely play significant roles in FPA disease development and reconstruction failure, but these deformations are poorly characterized. The goal of this study was to quantify axial compression and bending of human FPAs that are placed in positions commonly assumed during the normal course of daily activities. Retrievable nitinol markers were deployed using a custom-made catheter system into 28 in situ FPAs of 14 human cadavers. Contrast-enhanced, thin-section computed tomography images were acquired with each limb in the standing (180 degrees), walking (110 degrees), sitting (90 degrees), and gardening (60 degrees) postures. Image segmentation and analysis allowed relative comparison of spatial locations of each intra-arterial marker to determine axial compression and bending using the arterial centerlines. Axial compression in the popliteal artery (PA) was greater than in the proximal superficial femoral artery (SFA) or the adductor hiatus (AH) segments in all postures (P = .02). Average compression in the SFA, AH, and PA ranged from 9% to 15%, 11% to 19%, and 13% to 25%, respectively. The FPA experienced significantly more acute bending in the AH and PA segments compared with the proximal SFA (P < .05) in all postures. In the walking, sitting, and gardening postures, average sphere radii in the SFA, AH, and PA ranged from 21 to 27 mm, 10 to 18 mm, and 8 to 19 mm, whereas bending angles ranged from 150 to 157 degrees, 136 to 147 degrees, and 137 to 148 degrees, respectively. The FPA experiences significant axial compression and bending during limb flexion that occur at even modest limb angles. Moreover, different segments of the FPA appear to undergo significantly different degrees of deformation. Understanding the effects of limb flexion on axial compression and bending might assist with reconstructive device selection for patients requiring peripheral arterial disease intervention and may also help guide the development of devices with improved characteristics that can better adapt to the dynamic environment of the lower extremity vasculature. Copyright © 2017 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved.
Soehnel, Grant; Tanbakuchi, Anthony
2012-11-20
A custom IR spot scanning experiment was constructed to project subpixel spots on a mercury cadmium telluride focal plane array (FPA). The hardware consists of an FPA in a liquid nitrogen cooled Dewar, high precision motorized stages, a custom aspheric lens, and a 1.55 and 3.39 μm laser source. By controlling the position and intensity of the spot, characterizations of cross talk, saturation, blooming, and (indirectly) the minority carrier lifetime were performed. In addition, a Monte-Carlo-based charge diffusion model was developed to validate experimental data and make predictions. Results show very good agreement between the model and experimental data. Parameters such as wavelength, reverse bias, and operating temperature were found to have little effect on pixel crosstalk in the absorber layer of the detector. Saturation characterizations show that these FPAs, which do not have antiblooming circuitry, exhibit an increase in cross talk due to blooming at ∼39% beyond the flux required for analog saturation.
Sources and Implications of Bias and Uncertainty in a Century of US Wildfire Activity Data
NASA Astrophysics Data System (ADS)
Short, K.
2013-12-01
The statistical analysis of wildfire activity is a critical component of national wildfire planning, operations, and research in the United States (US). Wildfire activity data have been collected in the US for over a century. Yet, to this day, no single unified system of wildfire record-keeping exists. Data for analysis are generally harvested from archival summary reports from federal or interagency fire organizations; incident-level wildfire reporting systems of the federal, state, and local fire services; and, increasingly, remote-sensing programs. It is typical for research into wildfire activity patterns for all or part of the last century to require data from several of these sources and perhaps others. That work is complicated by the disunity of the various datasets and potentially compromised by inherent reporting biases, discussed here. The availability of wildfire records with the information content and geospatial precision generally sought for increasingly popular climatological analyses and the modeling of contemporary wildfire risk is limited to recent decades. We explain how the disunity and idiosyncrasies of US wildfire reporting have largely precluded true interagency, or all-lands, analyses of even recent wildfire activity and hamstrung some early risk modeling efforts. We then describe our efforts to acquire, standardize, error-check, compile, scrub, and evaluate the completeness of US federal, state, and local wildfire records from 1992-2011 for the national interagency Fire Program Analysis (FPA) application. The resulting FPA Fire-Occurrence Database (FPA FOD) includes nearly 1.6 million records from the 20-year period, with values for at least the following core data elements: location at least as precise as a Public Land Survey System section (2.6-km2 grid), discovery date, and final fire size. The FPA FOD is publicly available from the Research Data Archive of the US Department of Agriculture, Forest Service (http://dx.doi.org/10.2737/RDS-2013-0009). While necessarily incomplete in some aspects, the database is intended to facilitate fairly high-resolution geospatial analysis of wildfire activity over the past two decades, based on available information from the authoritative systems of record. Formal non-federal wildfire reporting has been on the rise over the past several decades, and users of national datasets like the FPA FOD must beware of state and local reporting biases to avoid drawing spurious conclusions when analysing the data. Apparent trends in the numbers and area burned by wildfires, for example, may be the result of multiple factors, including changes in climate, fuels, demographics (e.g. population density), fire-management policies, and - as we underscore here - levels of reporting.
NASA Astrophysics Data System (ADS)
Lawrence, Kurt C.; Park, Bosoon; Windham, William R.; Mao, Chengye; Poole, Gavin H.
2003-03-01
A method to calibrate a pushbroom hyperspectral imaging system for "near-field" applications in agricultural and food safety has been demonstrated. The method consists of a modified geometric control point correction applied to a focal plane array to remove smile and keystone distortion from the system. Once a FPA correction was applied, single wavelength and distance calibrations were used to describe all points on the FPA. Finally, a percent reflectance calibration, applied on a pixel-by-pixel basis, was used for accurate measurements for the hyperspectral imaging system. The method was demonstrated with a stationary prism-grating-prism, pushbroom hyperspectral imaging system. For the system described, wavelength and distance calibrations were used to reduce the wavelength errors to <0.5 nm and distance errors to <0.01mm (across the entrance slit width). The pixel-by-pixel percent reflectance calibration, which was performed at all wavelengths with dark current and 99% reflectance calibration-panel measurements, was verified with measurements on a certified gradient Spectralon panel with values ranging from about 14% reflectance to 99% reflectance with errors generally less than 5% at the mid-wavelength measurements. Results from the calibration method, indicate the hyperspectral imaging system has a usable range between 420 nm and 840 nm. Outside this range, errors increase significantly.
Desyatova, Anastasia; MacTaggart, Jason; Poulson, William; Deegan, Paul; Lomneth, Carol; Sandip, Anjali; Kamenskiy, Alexey
2017-06-01
Open and endovascular treatments for peripheral arterial disease are notorious for high failure rates. Severe mechanical deformations experienced by the femoropopliteal artery (FPA) during limb flexion and interactions between the artery and repair materials play important roles and may contribute to poor clinical outcomes. Computational modeling can help optimize FPA repair, but these simulations heavily depend on the choice of constitutive model describing the arterial behavior. In this study finite element model of the FPA in the standing (straight) and gardening (acutely bent) postures was built using computed tomography data, longitudinal pre-stretch and biaxially determined mechanical properties. Springs and dashpots were used to represent surrounding tissue forces associated with limb flexion-induced deformations. These forces were then used with age-specific longitudinal pre-stretch and mechanical properties to obtain deformed FPA configurations for seven age groups. Four commonly used invariant-based constitutive models were compared to determine the accuracy of capturing deformations and stresses in each age group. The four-fiber FPA model most accurately portrayed arterial behavior in all ages, but in subjects younger than 40 years, the performance of all constitutive formulations was similar. In older subjects, Demiray (Delfino) and classic two-fiber Holzapfel-Gasser-Ogden formulations were better than the Neo-Hookean model for predicting deformations due to limb flexion, but both significantly overestimated principal stresses compared to the FPA or Neo-Hookean models.
NASA Astrophysics Data System (ADS)
Khatri, Jaidev
This thesis examines themodeling, analysis, and control system design issues for scramjet powered hypersonic vehicles. A nonlinear three degrees of freedom longitudinal model which includes aero-propulsion-elasticity effects was used for all analyses. This model is based upon classical compressible flow and Euler-Bernouli structural concepts. Higher fidelity computational fluid dynamics and finite element methods are needed for more precise intermediate and final evaluations. The methods presented within this thesis were shown to be useful for guiding initial control relevant design. The model was used to examine the vehicle's static and dynamic characteristics over the vehicle's trimmable region. The vehicle has significant longitudinal coupling between the fuel equivalency ratio (FER) and the flight path angle (FPA). For control system design, a two-input two-output plant (FER - elevator to speed-FPA) with 11 states (including 3 flexible modes) was used. Velocity, FPA, and pitch were assumed to be available for feedback. Aerodynamic heat modeling and design for the assumed TPS was incorporated to original Bolender's model to study the change in static and dynamic properties. De-centralized control stability, feasibility and limitations issues were dealt with the change in TPS elasticity, mass and physical dimension. The impact of elasticity due to TPS mass, TPS physical dimension as well as prolonged heating was also analyzed to understand performance limitations of de-centralized control designed for nominal model.
Solís-Guzmán, María Gloria; Argüello-Astorga, Gerardo; López-Bucio, José; Ruiz-Herrera, León Francisco; López-Meza, Joel; Sánchez-Calderón, Lenin; Carreón-Abud, Yazmín; Martínez-Trujillo, Miguel
2017-01-01
Abstract Proteins of the Split ends (Spen) family are characterized by an N-terminal domain, with one or more RNA recognition motifs and a SPOC domain. In Arabidopsis thaliana, the Spen protein FPA is involved in the control of flowering time as a component of an autonomous pathway independent of photoperiod. The A. thaliana genome encodes another gene for a putative Spen protein at the locus At4g12640, herein named AtSpen2. Bioinformatics analysis of the AtSPEN2 SPOC domain revealed low sequence similarity with the FPA SPOC domain, which was markedly lower than that found in other Spen proteins from unrelated plant species. To provide experimental information about the function of AtSpen2, A. thaliana plants were transformed with gene constructs of its promoter region with uidA::gfp reporter genes; the expression was observed in vascular tissues of leaves and roots, as well as in ovules and developing embryos. There was absence of a notable phenotype in knockout and overexpressing lines, suggesting that its function in plants might be specific to certain endogenous or environmental conditions. Our results suggest that the function of Atspen2 diverged from that of fpa due in part to their different transcription expression pattern and divergence of the regulatory SPOC domain. PMID:28850635
Shury, Todd K; Bergeson, Doug; Surujballi, Om; Lyashchenko, Konstantin P; Greenwald, Rena
2014-08-01
Diagnosis of Mycobacterium bovis in wild populations is very challenging due to complications imposed by the use of traditional skin tests, poor sensitivity of gold standard tests which rely on culture of M. bovis from tissues and wide variations in severity of disease. Various combinations of a lymphocyte stimulation test (LST), fluorescence polarization assay (FPA) and the Cervid TB Stat-Pak were evaluated using two different validation approaches: a latent class analysis and classical statistical approach using culture as a gold standard. A validation subsample consisting of animals culled for population control and mortalities from capture provided an unbiased estimate of test performance for comparison. The sensitivity of the LST (0.83, 95% CI: [0.70-0.97] as a single test was similar to existing tuberculin skin tests, but the sensitivity of the FPA (0.40, 95% CI: [0.22-0.58]) and Cervid TB Stat-Pak (0.62, 95% CI: [0.41-0.83]) were lower in this population. Test performance of the LST and Cervid TB Stat-Pak in parallel was similar to the use of all three tests in parallel and inclusion of the FPA did not greatly enhance test performance. Prevalence of M. bovis in elk varied substantially between the high risk area of southern Manitoba (9.1%, 95% CI: [6.09-12.1%]) and lower risk areas outside this zone (0.76%, 95% CI: [0-2.26%]). Bayesian latent class analysis indicated lack of covariance between the two antibody tests (FPA and Cervid TB Stat-Pak) while the classical two-stage analysis indicated there was conditional dependence between the tests. All three tests when used in parallel resulted in 100% NPV using all three validation methods, indicating few elk were misclassified as false negative by post mortem culture. Similar to previous studies, this study found that combinations of blood tests that utilize cell mediated responses along with humoral antibody responses maximize the sensitivity of tests for diagnosis of M. bovis in wild cervid populations. Copyright © 2013 CROWN COPYRIGHT and Elsevier B.V. Published by Elsevier B.V. All rights reserved.
ICC Type II large-format FPA detector assemblies
NASA Astrophysics Data System (ADS)
Clynne, Thomas H.; Powers, Thomas P.
1997-08-01
ICC presents a new addition to their integrated detector assembly product line with the announcement of their type II large format staring class FPA units. A result of internally funded research and development, the ICC type II detector assembly can accommodate all existing large format staring class PtSi, InSb and MCT focal planes, up to 640 by 480. Proprietary methodologies completely eliminate all FPA stresses to allow for maximum FPA survivability. Standard optical and cryocooler interfaces allow for the use of BEI, AEG, TI SADA Hughes/Magnavox and Joule Thompson coolers. This unit has been qualified to the current SADA II thermal environmental specifications and was tailored around ICC's worldwide industry standard type IV product. Assembled in a real world flexible manufacturing environment, this unit features a wide degree of adaptability and can be easily modified to a user's specifications via standard options and add-ons that include optical interfaces, electrical interfaces and window/filter material selections.
NASA Astrophysics Data System (ADS)
Herraiz, M.; de Vicente, G.; Lindo-Ñaupari, R.; Giner, J.; Simón, J. L.; GonzáLez-Casado, J. M.; Vadillo, O.; RodríGuez-Pascua, M. A.; CicuéNdez, J. I.; Casas, A.; CabañAs, L.; Rincón, P.; CortéS, A. L.; RamíRez, M.; Lucini, M.
2000-08-01
A general synthesis of the recent and present stress situation and evolution in the Iberian Peninsula was obtained from microstructural and seismological analysis. The stress evolution was deduced from (1) fault population analysis (FPA) from 409 sites distributed throughout the Iberian Peninsula, (2) paleostress indicators given by 324 stations taken from the bibliography, and (3) seismic data corresponding to 161 focal mechanisms evenly spread in the studied region. The application of FPA together with the determination of stress tensors and focal mechanisms for the whole Iberian microplate has provided two main results: (1) the Iberian Peninsula is undergoing a NW-SE oriented compression, except for the northeastern part (Pyrenees, Ebro Basin, and Iberian Chain), where it is N-S to NE-SW, and the Gulf of Cádiz, where it seems to be E-W, and (2) the main trends of the stress field have remained almost constant since the upper Miocene. The analysis performed by zones suggests the presence of local heterogeneities in the stress field.
Constitutive description of human femoropopliteal artery aging.
Kamenskiy, Alexey; Seas, Andreas; Deegan, Paul; Poulson, William; Anttila, Eric; Sim, Sylvie; Desyatova, Anastasia; MacTaggart, Jason
2017-04-01
Femoropopliteal artery (FPA) mechanics play a paramount role in pathophysiology and the artery's response to therapeutic interventions, but data on FPA mechanical properties are scarce. Our goal was to characterize human FPAs over a wide population to derive a constitutive description of FPA aging to be used for computational modeling. Fresh human FPA specimens ([Formula: see text]) were obtained from [Formula: see text] predominantly male (80 %) donors 54±15 years old (range 13-82 years). Morphometric characteristics including radius, wall thickness, opening angle, and longitudinal pre-stretch were recorded. Arteries were subjected to multi-ratio planar biaxial extension to determine constitutive parameters for an invariant-based model accounting for the passive contributions of ground substance, elastin, collagen, and smooth muscle. Nonparametric bootstrapping was used to determine unique sets of material parameters that were used to derive age-group-specific characteristics. Physiologic stress-stretch state was calculated to capture changes with aging. Morphometric and constitutive parameters were derived for seven age groups. Vessel radius, wall thickness, and circumferential opening angle increased with aging, while longitudinal pre-stretch decreased ([Formula: see text]). Age-group-specific constitutive parameters portrayed orthotropic FPA stiffening, especially in the longitudinal direction. Structural changes in artery wall elastin were associated with reduction of physiologic longitudinal and circumferential stretches and stresses with age. These data and the constitutive description of FPA aging shed new light on our understanding of peripheral arterial disease pathophysiology and arterial aging. Application of this knowledge might improve patient selection for specific treatment modalities in personalized, precision medicine algorithms and could assist in device development for treatment of peripheral artery disease.
MTF measurements of a type-II superlattice infrared focal plane array sealed in a cryocooler.
Nghiem, Jean; Jaeck, Julien; Primot, Jerome; Coudrain, Christophe; Derelle, Sophie; Huard, Edouard; Caes, Marcel; Bernhardt, Sylvie; Haidar, Riad; Christol, Philippe; Ribet-Mohamed, Isabelle
2018-04-16
In operational electro-optical systems, infrared focal plane arrays (IR FPA) are integrated in cryocoolers which induce vibrations that may strongly affect their modulation transfer function (MTF). In this paper, we present the MTF measurement of an IR FPA sealed in its cryocooler. The method we use to measure the MTF decorrelates operational constraints and the technological limitations of the IR FPA. The bench is based on the diffraction properties of a continuously self imaging grating (CSIG). The 26 µm pixel size extracted from the MTF measurement is in good agreement with the expected value.
NASA Astrophysics Data System (ADS)
Bowers, David L.; Boger, James K.; Wellems, L. David; Black, Wiley T.; Ortega, Steve E.; Ratliff, Bradley M.; Fetrow, Matthew P.; Hubbs, John E.; Tyo, J. Scott
2006-05-01
Recent developments for Long Wave InfraRed (LWIR) imaging polarimeters include incorporating a microgrid polarizer array onto the focal plane array (FPA). Inherent advantages over typical polarimeters include packaging and instantaneous acquisition of thermal and polarimetric information. This allows for real time video of thermal and polarimetric products. The microgrid approach has inherent polarization measurement error due to the spatial sampling of a non-uniform scene, residual pixel to pixel variations in the gain corrected responsivity and in the noise equivalent input (NEI), and variations in the pixel to pixel micro-polarizer performance. The Degree of Linear Polarization (DoLP) is highly sensitive to these parameters and is consequently used as a metric to explore instrument sensitivities. Image processing and fusion techniques are used to take advantage of the inherent thermal and polarimetric sensing capability of this FPA, providing additional scene information in real time. Optimal operating conditions are employed to improve FPA uniformity and sensitivity. Data from two DRS Infrared Technologies, L.P. (DRS) microgrid polarizer HgCdTe FPAs are presented. One FPA resides in a liquid nitrogen (LN2) pour filled dewar with a 80°K nominal operating temperature. The other FPA resides in a cryogenic (cryo) dewar with a 60° K nominal operating temperature.
Suomi NPP VIIRS Prelaunch and On-orbit Geometric Calibration and Characterization
NASA Technical Reports Server (NTRS)
Wolfe, Robert E.; Lin, Guoqing; Nishihama, Masahiro; Tewari, Krishna P.; Tilton, James C.; Isaacman, Alice R.
2013-01-01
The Visible Infrared Imager Radiometer Suite (VIIRS) sensor was launched 28 October 2011 on the Suomi National Polarorbiting Partnership (SNPP) satellite. VIIRS has 22 spectral bands covering the spectrum between 0.412 m and 12.01 m, including 16 moderate resolution bands (M-bands) with a spatial resolution of 750 m at nadir, 5 imaging resolution bands (I-bands) with a spatial resolution of 375 m at nadir, and 1 day-night band (DNB) with a near-constant 750 m spatial resolution throughout the scan. These bands are located in a visible and near infrared (VisNIR) focal plane assembly (FPA), a short- and mid-wave infrared (SWMWIR) FPA and a long-wave infrared (LWIR) FPA. All bands, except the DNB, are co-registered for proper environmental data records (EDRs) retrievals. Observations from VIIRS instrument provide long-term measurements of biogeophysical variables for climate research and polar satellite data stream for the operational communitys use in weather forecasting and disaster relief and other applications. Well Earth-located (geolocated) instrument data is important to retrieving accurate biogeophysical variables. This paper describes prelaunch pointing and alignment measurements, and the two sets of on-orbit correction of geolocation errors, the first of which corrected error from 1,300 m to within 75 m (20 I-band pixel size), and the second of which fine tuned scan angle dependent errors, bringing VIIRS geolocation products to high maturity in one and a half years of the SNPP VIIRS on-orbit operations. Prelaunch calibration and the on-orbit characterization of sensor spatial impulse responses and band-to-band co-registration (BBR) are also described.
Discussion about photodiode architectures for space applications
NASA Astrophysics Data System (ADS)
Gravrand, O.; Destefanis, G.; Cervera, C.; Zanatta, J.-P.; Baier, N.; Ferron, A.; Boulade, O.
2017-11-01
Detection for space application is very demanding on the IR detector: all wavelengths, from visible-NIR (2- 3um cutoff) to LWIR (10-12.5um cutoff), even sometimes VLWIR (15um cutoff) may be of interest. Moreover, various scenarii are usually considered. Some are imaging applications where the focal plane array (FPA) is used as an optical element to sense an image. However, the FPA may also be used in spectrometric applications where light is triggered on the different pixels depending on its wavelength. In some cases, star pointing is another use of FPAs where the retina is used to sense the position of the satellite. In all those configurations, we might distinguish several categories of applications: • low flux applications where the FPA is staring at space and the detection occurs with only a few number of photons. • high flux applications where the FPA is usually staring at the earth. In this case, the black body emission of the earth and its atmosphere ensures usually a large number of photons to perform the detection. Those two different categories are highly dimensioning for the detector as it usually determines the level of dark current and quantum efficiency (QE) requirements. Indeed, high detection performance usually requires a large number of integrated photons such that high QE is needed for low flux applications, in order to limit the integration time as much as possible. Moreover, dark current requirement is also directly linked to the expected incoming flux, in order to limit as much as possible the SNR degradation due to dark charges vs photocharges. Note that in most cases, this dark current is highly depending on operating temperature which dominates detector consumption. A classical way to mitigate dark current is to cool down the detector to very low temperatures. This paper won't discuss the need for wavefront sensing where the number of detected photons is low because of a very narrow integration window. Rigorously, this kind of configuration is a low flux application but the need for speed distinguishes it from other low flux applications as it usually requires a different ROIC architecture and a photodiode optimized for high response speed.
Cao, Yanpeng; Tisse, Christel-Loic
2013-09-01
In uncooled long-wave infrared (LWIR) microbolometer imaging systems, temperature fluctuations of the focal plane array (FPA) result in thermal drift and spatial nonuniformity. In this paper, we present a novel approach based on single-image processing to simultaneously estimate temperature variances of FPAs and compensate the resulting temperature-dependent nonuniformity. Through well-controlled thermal calibrations, empirical behavioral models are derived to characterize the relationship between the responses of microbolometer and FPA temperature variations. Then, under the assumption that strong dependency exists between spatially adjacent pixels, we estimate the optimal FPA temperature so as to minimize the global intensity variance across the entire thermal infrared image. We make use of the estimated FPA temperature to infer an appropriate nonuniformity correction (NUC) profile. The performance and robustness of the proposed temperature-adaptive NUC method are evaluated on realistic IR images obtained by a 640 × 512 pixels uncooled LWIR microbolometer imaging system operating in a significantly changed temperature environment.
Measurement of filter paper activities of cellulase with microplate-based assay.
Yu, Xiaoxiao; Liu, Yan; Cui, Yuxiao; Cheng, Qiyue; Zhang, Zaixiao; Lu, Jia Hui; Meng, Qingfan; Teng, Lirong; Ren, Xiaodong
2016-01-01
It is always a challenge to determine the total cellulase activity efficiently without reducing accuracy. The most common total cellulase activity assay is the filter paper assay (FPA) established by the International Union of Pure and Applied Chemistry (IUPAC). A new procedure to measure the FPA with microplate-based assay was studied in this work, which followed the main idea of IUPAC to dilute cellulase preparation to get fixed glucose release. FPAs of six cellulase preparations were determined with the microplate-based assay. It is shown that FPAs of cellulase Youtell, RCconc, R-10, Lerkam, Yishui and Sinopharm were 67.9, 46.0, 46.1, 27.4, 7.6 and 8.0 IU/ml respectively. There was no significant difference at the 95% confidence level between the FPA determined with IUPAC and the microplate-based assay. It could be concluded that the FPA could be determined by the microplate-based assay with the same accuracy and much more efficiency compared with that by IUPAC.
Measurement of filter paper activities of cellulase with microplate-based assay
Yu, Xiaoxiao; Liu, Yan; Cui, Yuxiao; Cheng, Qiyue; Zhang, Zaixiao; Lu, Jia Hui; Meng, Qingfan; Teng, Lirong; Ren, Xiaodong
2015-01-01
It is always a challenge to determine the total cellulase activity efficiently without reducing accuracy. The most common total cellulase activity assay is the filter paper assay (FPA) established by the International Union of Pure and Applied Chemistry (IUPAC). A new procedure to measure the FPA with microplate-based assay was studied in this work, which followed the main idea of IUPAC to dilute cellulase preparation to get fixed glucose release. FPAs of six cellulase preparations were determined with the microplate-based assay. It is shown that FPAs of cellulase Youtell, RCconc, R-10, Lerkam, Yishui and Sinopharm were 67.9, 46.0, 46.1, 27.4, 7.6 and 8.0 IU/ml respectively. There was no significant difference at the 95% confidence level between the FPA determined with IUPAC and the microplate-based assay. It could be concluded that the FPA could be determined by the microplate-based assay with the same accuracy and much more efficiency compared with that by IUPAC. PMID:26858572
Generalized algebraic scene-based nonuniformity correction algorithm.
Ratliff, Bradley M; Hayat, Majeed M; Tyo, J Scott
2005-02-01
A generalization of a recently developed algebraic scene-based nonuniformity correction algorithm for focal plane array (FPA) sensors is presented. The new technique uses pairs of image frames exhibiting arbitrary one- or two-dimensional translational motion to compute compensator quantities that are then used to remove nonuniformity in the bias of the FPA response. Unlike its predecessor, the generalization does not require the use of either a blackbody calibration target or a shutter. The algorithm has a low computational overhead, lending itself to real-time hardware implementation. The high-quality correction ability of this technique is demonstrated through application to real IR data from both cooled and uncooled infrared FPAs. A theoretical and experimental error analysis is performed to study the accuracy of the bias compensator estimates in the presence of two main sources of error.
Code of Federal Regulations, 2010 CFR
2010-04-01
..., including, but not limited to, those that both before and after the transaction remain under the functional...) Transactions that do not require an Appendix A analysis; 1 and 1 Inquiry Concerning the Commission's Merger...
2014-10-31
Hole .......................................................4 2. SOHO EIT Image with Coronal Holes and FPA Vector...Diagram of CME Deflection by a Coronal Hole Figure 2: SOHO EIT Image with Coronal Holes and FPA Vector Approved for public release; distribution
Frade, A; Vilar, D
1991-05-01
The article on sex education in Portugal covers background, the educational system, the clashes of the 1960's over sex education, the Committee for the Study of Sexuality and Education (CSSE), the policies, politics and social movements during the period 1974 - 1984, the discussions in Parliament, the 1988 Reform of the Educational System, the Family Planning Association (FPA) and sex education, and the future role of the FPA. It was not until the institution of the multiparity parliamentary system in 1974 that discussing social and political changes was possible, culminating in 1984 with new legislation on abortion, family planning, and sex education. School reform came in 1987/8 with the Ministry of Education primarily responsible for curricula. The 1960's brought with it the influence of the Catholic Church. Change came in the form of progressivism among Catholics who replaced dogma with dialogue and listening. Sex education was considered as preparation for marriage, but masturbation, contraception, and prostitution were also discussed. In addition, the founder of FPA chaired the CSSE in 1971 and opened up debate on sex issues and drafted a bill to establish co-education in Portuguese schools. The revolution of 1974 brought an end to censorship and brought forth a policy of developing family planning. Changed in the Family Code gave women greater equality. UNFPA supported teacher training in non-sexist education. With human reproduction included in the natural sciences, there was still no school sex education policy and contraception was only sometimes represented in the biology curriculum. The focus of FPA was on contraception and abortion. Finally in the 1980's, the first sex education programs were developed for out-of-school youth. Even though in the 1970's there were leftists groups promoting sex education, it took leftist parliamentary power to get legislation on sex education in the schools adopted. The Ministry of Education however was pressured by the Catholic Church. As in 1973, committees were formed but no action was taken. Sex education activity increased nonetheless - the first FPA document on school education prepared. In 1986 Personal and Social Education was approved by parliament providing an alternative (due to the Catholic Church) to Religious Education, but even with FPA support documents, the implementation did not begin until the end of 1990. In brief the FPA's emphasis was on the body, sexuality, sex and interpersonal relationships, and sexual reproduction. The role of FPA continues at the grass roots level in stimulating discussion; cooperating with schools, students and parents; and acting as a resource center.
Sun, Fubao Fuebiol; Hong, Jiapeng; Hu, Jinguang; Saddler, Jack N; Fang, Xu; Zhang, Zhenyu; Shen, Song
2015-11-01
The potential of cellulase enzymes in the developing and ongoing "biorefinery" industry has provided a great motivation to develop an efficient cellulase mixture. Recent work has shown how important the role that the so-called accessory enzymes can play in an effective enzymatic hydrolysis. In this study, three newest Novozymes Cellic CTec cellulase preparations (CTec 1/2/3) were compared to hydrolyze steam pretreated lignocellulosic substrates and model substances at an identical FPA loading. These cellulase preparations were found to display significantly different hydrolytic performances irrelevant with the FPA. And this difference was even observed on the filter paper itself when the FPA based assay was revisited. The analysis of specific enzyme activity in cellulase preparations demonstrated that different accessory enzymes were mainly responsible for the discrepancy of enzymatic hydrolysis between diversified substrates and various cellulases. Such the active role of accessory enzymes present in cellulase preparations was finally verified by supplementation with β-glucosidase, xylanase and lytic polysaccharide monooxygenases AA9. This paper provides new insights into the role of accessory enzymes, which can further provide a useful reference for the rational customization of cellulase cocktails in order to realize an efficient conversion of natural lignocellulosic substrates. Copyright © 2015 Elsevier Inc. All rights reserved.
Limb flexion-induced twist and associated intramural stresses in the human femoropopliteal artery.
Desyatova, Anastasia; Poulson, William; Deegan, Paul; Lomneth, Carol; Seas, Andreas; Maleckis, Kaspars; MacTaggart, Jason; Kamenskiy, Alexey
2017-03-01
High failure rates of femoropopliteal artery (FPA) interventions are often attributed to severe mechanical deformations that occur with limb movement. Torsion of the FPA likely plays a significant role, but is poorly characterized and the associated intramural stresses are currently unknown. FPA torsion in the walking, sitting and gardening postures was characterized in n = 28 in situ FPAs using intra-arterial markers. Principal mechanical stresses and strains were quantified in the superficial femoral artery (SFA), adductor hiatus segment (AH) and the popliteal artery (PA) using analytical modelling. The FPA experienced significant torsion during limb flexion that was most severe in the gardening posture. The associated mechanical stresses were non-uniformly distributed along the length of the artery, increasing distally and achieving maximum values in the PA. Maximum twist in the SFA ranged 10-13° cm -1 , at the AH 8-16° cm -1 , and in the PA 14-26° cm -1 in the walking, sitting and gardening postures. Maximum principal stresses were 30-35 kPa in the SFA, 27-37 kPa at the AH and 39-43 kPa in the PA. Understanding torsional deformations and intramural stresses in the FPA can assist with device selection for peripheral arterial disease interventions and may help guide the development of devices with improved characteristics. © 2017 The Author(s).
Innovative compact focal plane array for wide field vis and ir orbiting telescopes
NASA Astrophysics Data System (ADS)
Hugot, Emmanuel; Vives, Sébastien; Ferrari, Marc; Gaeremynck, Yann; Jahn, Wilfried
2017-11-01
The future generation of high angular resolution space telescopes will require breakthrough technologies to combine large diameters and large focal plane arrays with compactness and lightweight mirrors and structures. Considering the allocated volume medium-size launchers, short focal lengths are mandatory, implying complex optical relays to obtain diffraction limited images on large focal planes. In this paper we present preliminary studies to obtain compact focal plane arrays (FPA) for earth observations on low earth orbits at high angular resolution. Based on the principle of image slicers, we present an optical concept to arrange a 1D FPA into a 2D FPA, allowing the use of 2D detector matrices. This solution is particularly attractive for IR imaging requiring a cryostat, which volume could be considerably reduced as well as the relay optics complexity. Enabling the use of 2D matrices for such an application offers new possibilities. Recent developments on curved FPA allows optimization without concerns on the field curvature. This innovative approach also reduces the complexity of the telescope optical combination, specifically for fast telescopes. This paper will describe the concept and optical design of an F/5 - 1.5m telescope equipped with such a FPA, the performances and the impact on the system with a comparison with an equivalent 1.5m wide field Korsch telescope.
Proton affinity and enthalpy of formation of formaldehyde
NASA Astrophysics Data System (ADS)
Czakó, Gábor; Nagy, Balázs; Tasi, Gyula; Somogyi, Árpád; Šimunek, Ján; Noga, Jozef; Braams, Bastiaan J.; Bowman, Joel M.; Császár; , Attila G.
The proton affinity and the enthalpy of formation of the prototypical carbonyl, formaldehyde, have been determined by the first-principles composite focal-point analysis (FPA) approach. The electronic structure computations employed the all-electron coupled-cluster method with up to single, double, triple, quadruple, and even pentuple excitations. In these computations the aug-cc-p(C)VXZ [X = 2(D), 3(T), 4(Q), 5, and 6] correlation-consistent Gaussian basis sets for C and O were used in conjunction with the corresponding aug-cc-pVXZ (X = 2-6) sets for H. The basis set limit values have been confirmed via explicitly correlated computations. Our FPA study supersedes previous computational work for the proton affinity and to some extent the enthalpy of formation of formaldehyde by accounting for (a) electron correlation beyond the "gold standard" CCSD(T) level; (b) the non-additivity of core electron correlation effects; (c) scalar relativity; (d) diagonal Born-Oppenheimer corrections computed at a correlated level; (e) anharmonicity of zero-point vibrational energies, based on global potential energy surfaces and variational vibrational computations; and (f) thermal corrections to enthalpies by direct summation over rovibrational energy levels. Our final proton affinities at 298.15 (0.0) K are ΔpaHo (H2CO) = 711.02 (704.98) ± 0.39 kJ mol-1. Our final enthalpies of formation at 298.15 (0.0) K are ΔfHo (H2CO) = -109.23 (-105.42) ± 0.33 kJ mol-1. The latter values are based on the enthalpy of the H2 + CO → H2CO reaction but supported by two further reaction schemes, H2O + C → H2CO and 2H + C + O → H2CO. These values, especially ΔpaHo (H2CO), have better accuracy and considerably lower uncertainty than the best previous recommendations and thus should be employed in future studies.
NASA Astrophysics Data System (ADS)
Garcilazo, H.; Valcarce, A.; Vijande, J.
2017-07-01
Using local central Yukawa-type Malfliet-Tjon interactions reproducing the low-energy parameters and phase shifts of the nn system, and the latest updates of the nΛ and ΛΛ Nijmegen ESC08c potentials, we study the possible existence of a bound state. Our results indicate that the is unbound, being just above threshold. We discuss the role played by the 1 S 0 nn repulsive term of the Yukawa-type Malfliet-Tjon interaction. Supported by COFAA-IPN (México), Ministerio de Economía, Industria y Competitividad and EU FEDER (FPA2013-47443, FPA2015-69714-REDT, FPA2016-77177), Junta de Castilla y León (SA041U16) and Generalitat Valenciana PrometeoII/2014/066
Absolute stellar photometry on moderate-resolution FPA images
Stone, T.C.
2009-01-01
An extensive database of star (and Moon) images has been collected by the ground-based RObotic Lunar Observatory (ROLO) as part of the US Geological Survey program for lunar calibration. The stellar data are used to derive nightly atmospheric corrections for the observations from extinction measurements, and absolute calibration of the ROLO sensors is based on observations of Vega and published reference flux and spectrum data. The ROLO telescopes were designed for imaging the Moon at moderate resolution, thus imposing some limitations for the stellar photometry. Attaining accurate stellar photometry with the ROLO image data has required development of specialized processing techniques. A key consideration is consistency in discriminating the star core signal from the off-axis point spread function. The analysis and processing methods applied to the ROLO stellar image database are described. ?? 2009 BIPM and IOP Publishing Ltd.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-13
...--Criteria for Qualifying Conduit Hydropower Facility Satisfies (Y/ Statutory provision Description N) FPA 30(a)(3)(A), as amended by The conduit the Y HREA. facility uses is a tunnel, canal, pipeline, aqueduct... agricultural, municipal, or industrial consumption and not primarily for the generation of electricity. FPA 30...
Chemical imaging of cotton fibers using an infrared microscope and a focal-plane array detector
USDA-ARS?s Scientific Manuscript database
In this presentation, the chemical imaging of cotton fibers with an infrared microscope and a Focal-Plane Array (FPA) detector will be discussed. Infrared spectroscopy can provide us with information on the structure and quality of cotton fibers. In addition, FPA detectors allow for simultaneous spe...
Evaluation of Primary Binding Assays for Presumptive Serodiagnosis of Swine Brucellosis in Argentina
Paulo, P. Silva; Vigliocco, A. M.; Ramondino, R. F.; Marticorena, D.; Bissi, E.; Briones, G.; Gorchs, C.; Gall, D.; Nielsen, K.
2000-01-01
An indirect enzyme-linked immunosorbent assay (IELISA), a competitive ELISA (CELISA), and a fluorescence polarization assay (FPA) for the presumptive serological diagnosis of swine brucellosis were evaluated using two populations of swine sera: sera from brucellosis-free Canadian herds and sera from Argentina selected based on positive reactions in the buffered antigen plate agglutination test (BPAT) and the 2-mercaptoethanol (2-ME) test. In addition, sera from adult swine from which Brucella suis was isolated at least once for each farm of origin were evaluated. The IELISA, CELISA, and FPA specificity values were 99.9, 99.5, and 98.3%, respectively, and the IELISA, CELISA, and FPA sensitivity values relative to the BPAT and the 2-ME test were 98.9, 96.6, and 93.8%, respectively. Actual sensitivity was assessed by using 37 sera from individual pigs from which B. suis was cultured, and the values obtained were as follows: BPAT, 86.5%; 2-ME test, 81.1%; IELISA, 86.5%; CELISA, 78.5%; and FPA, 80.0%. PMID:10973463
Corrugated Quantum Well Infrared Photodetector Focal Plane Array Test Results
NASA Technical Reports Server (NTRS)
Goldberg, A.; Choi, K. K.; Das, N. C.; La, A.; Jhabvala, M.
1999-01-01
The corrugated quantum-well infrared photodetector (C-QWIP) uses total internal reflection to couple normal incident light into the optically active quantum wells. The coupling efficiency has been shown to be relatively independent of the pixel size and wavelength thus making the C-QWIP a candidate for detectors over the entire infrared spectrum. The broadband coupling efficiency of the C-QWIP makes it an ideal candidate for multiwavelength detectors. We fabricated and tested C-QWIP focal plane arrays (FPAs) with cutoff wavelengths of 11.2 and 16.2 micrometers. Each FPA has 256 x 256 pixels that are bump-bonded to a direct injection readout circuit. Both FPAs provided infrared imagery with good aesthetic attributes. For the 11.2-micrometers FPA, background-limited performance (BLIP) was observed at 60 K with f/3 optics. For the 16.2-micrometers FPA, BLIP was observed at 38 K. Besides the reduction of dark current in C-QWIP structures, the measured internal quantum efficiency (eta) remains to be high. The values for responsivity and quantum efficiency obtained from the FPA results agree well with those measured for single devices.
Fiducial Marker Detection and Pose Estimation From LIDAR Range Data
2010-03-01
of View FPA Focal Plane Array FPS Frames Per Second FRE Fiducial Registration Error GIS Geographic Information Systems GPS Global...applications to image analysis and automated cartography. Communications of the ACM, 24(6), 381–395. Bradski, G., & Kaehler, A. (2008). Learning OpenCV
Compact high-efficiency linear cryocooler in single-piston moving magnet design for HOT detectors
NASA Astrophysics Data System (ADS)
Rühlich, I.; Mai, M.; Rosenhagen, C.; Withopf, A.; Zehner, S.
2012-06-01
State of the art Mid Wave IR-technology has the potential to rise the FPA temperature from 77K to 130-150K (High Operation Temperature, HOT). Using a HOT FPA will significantly lower SWaP and keep those parameters finally dominated by the employed cryocooler. Therefore, compact high performance cryocoolers are mandatory. AIM has developed the SX040 cooler, optimized for FPA temperatures of about 95K (presented at SPIE 2010). The SX040 cooler incorporates a high efficient dual piston driving mechanism resulting in a very compact compressor of less than 100mm length. Higher compactness - especially shorter compressors - can be achieved by change from dual to single piston design. The new SX030 compressor has such a single piston Moving Magnet driving mechanism resulting in a compressor length of about 60mm. Common for SX040 and SX030 family is a Moving Magnet driving mechanism with coils placed outside the helium vessel. In combination with high performance plastics for the piston surfaces this design enables lifetimes in excess of 20,000h MTTF. Because of the higher FPA temperature and a higher operating frequency also a new displacer needs to be developed. Based on the existing 1/4" coldfinger interface AIM developed a new displacer optimized for an FPA temperature of 140K and above. This paper gives an overview on the development of this new compact single piston cryocooler. Technical details and performance data will be shown.
Carve, Megan; Coggan, Timothy L; Myers, Jackie H; Clarke, Bradley; Nugegoda, Dayanthi; Shimeta, Jeff
2018-02-01
The herbicide Fusilade Forte ® (FF) is widely applied in agricultural weed management and in the management of the invasive saltmarsh grass, Spartina anglica (ricegrass or cordgrass). FF (active ingredient fluazifop-P acid, FPA) is selective for poaceous grasses. Its primary mode of action is inhibition of the acetyl coenzyme-A carboxylase (ACCase) specific to this taxonomic group, and its secondary mode is by promotion of oxidative stress. FF is applied to S. anglica infestations in the intertidal zone, in proximity to seagrass meadows. Despite the potential for vital seagrass ecosystems to be exposed to FF, there is limited knowledge of any potential impacts. We investigated impacts of FPA on the endemic Australian seagrass, Zostera nigricaulis, measuring ACCase activity and parameters that reflect oxidative stress: photosynthetic performance, lipid peroxidation and photosynthetic pigment content. Seagrass was exposed to FF (0.01-10mgL -1 FPA and a control) for 7d, followed by a 7-d recovery in uncontaminated seawater. An enzyme assay demonstrated that FPA ≤10mgL -1 did not inhibit the activity of ACCase isolated from Z. nigricaulis, demonstrating that this seagrass is resistant to FF's primary mode of action. However, physiological impacts occurred following 7 days exposure to ≥0.1mgL -1 FPA, including up to a 72% reduction in photosynthetic pigment concentration. After 7-d recovery, photosynthetic pigment content improved in treatment plants; however, treated plants exhibited higher levels of lipid peroxidation. This study demonstrates that while Z. nigricaulis is resistant to FF's primary mode of action, significant physiological impacts occur following 7 days exposure to ≥0.1mgL -1 FPA. This study provides valuable information on the effects of FF on a non-target species that can better inform approaches to Spartina management in coastal seagrass ecosystems. Copyright © 2017 Elsevier B.V. All rights reserved.
Aircraft Survivability: Susceptibility Reduction, Spring 2003
2003-01-01
approach to implementing the real-time nonuniformity correction (NUC) hardware. Packaging and size constraints would not prohibit the future...92 Hz MWIR #3 Imager 640x512 InSb FPA Band: 3µm–5µm Pixel size: 24µm Max frame rate: 92 Hz LWIR Imager 640x512 HgCdTe FPA Band: 3µm–5µm Pixel size
Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-21
...--Criteria for Qualifying Conduit Hydropower Facility Satisfies (Y/ Statutory provision Description N) FPA 30(a)(3)(A), as amended by The conduit the Y HREA. facility uses is a tunnel, canal, pipeline, aqueduct... agricultural, municipal, or industrial consumption and not primarily for the generation of electricity. FPA 30...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-02
... trade associations and other organizations representing the interests of government and/or cooperatively... section 201(f) provides in relevant part that [n]o provision in [Part II of the FPA] shall apply to, or be... very small number of electric cooperatives that are not described by FPA section 201(f). Petitioners...
640 x 480 MWIR and LWIR camera system developments
NASA Astrophysics Data System (ADS)
Tower, John R.; Villani, Thomas S.; Esposito, Benjamin J.; Gilmartin, Harvey R.; Levine, Peter A.; Coyle, Peter J.; Davis, Timothy J.; Shallcross, Frank V.; Sauer, Donald J.; Meyerhofer, Dietrich
1993-01-01
The performance of a 640 x 480 PtSi, 3,5 microns (MWIR), Stirling cooled camera system with a minimum resolvable temperature of 0.03 is considered. A preliminary specification of a full-TV resolution PtSi radiometer was developed using the measured performance characteristics of the Stirling cooled camera. The radiometer is capable of imaging rapid thermal transients from 25 to 250 C with better than 1 percent temperature resolution. This performance is achieved using the electronic exposure control capability of the MOS focal plane array (FPA). A liquid nitrogen cooled camera with an eight-position filter wheel has been developed using the 640 x 480 PtSi FPA. Low thermal mass packaging for the FPA was developed for Joule-Thomson applications.
640 x 480 MWIR and LWIR camera system developments
NASA Astrophysics Data System (ADS)
Tower, J. R.; Villani, T. S.; Esposito, B. J.; Gilmartin, H. R.; Levine, P. A.; Coyle, P. J.; Davis, T. J.; Shallcross, F. V.; Sauer, D. J.; Meyerhofer, D.
The performance of a 640 x 480 PtSi, 3,5 microns (MWIR), Stirling cooled camera system with a minimum resolvable temperature of 0.03 is considered. A preliminary specification of a full-TV resolution PtSi radiometer was developed using the measured performance characteristics of the Stirling cooled camera. The radiometer is capable of imaging rapid thermal transients from 25 to 250 C with better than 1 percent temperature resolution. This performance is achieved using the electronic exposure control capability of the MOS focal plane array (FPA). A liquid nitrogen cooled camera with an eight-position filter wheel has been developed using the 640 x 480 PtSi FPA. Low thermal mass packaging for the FPA was developed for Joule-Thomson applications.
SWIR HgCdTe avalanche photiode focal plane array performances evaluation
NASA Astrophysics Data System (ADS)
de Borniol, E.; Rothman, J.; Salveti, F.; Feautrier, P.
2017-11-01
One of the main challenges of modern astronomical instruments like adaptive optics (AO) systems or fringe trackers is to deal with the very low photons flux detection scenarios. The typical timescale of atmospheric turbulences being in the range of some tens of milliseconds, infrared wavefront sensors for AO systems needs frame rates higher than 1 KHz leading to integration times lower than 1 ms. This integration time associated with a low irradiance results in a few number of integrated photons per frame per pixel. To preserve the information coming from this weak signal, the focal plane array (FPA) has to present a low read out noise, a high quantum efficiency and a low dark current. Up to now, the output noise of high speed near infrared sensors is limited by the silicon read out circuit noise. The use of HgCdTe avalanche photodiodes with high gain at moderate reverse bias and low excess noise seems then a logical way to reduce the impact of the read noise on images signal to noise ratio. These low irradiance passive imaging applications with integration times in the millisecond range needs low photodiode dark current and low background current. These requirements lead to the choice of the photodiode cut off wavelength. The short wave infrared (SWIR) around 3 μm is a good compromise between the gain that can be obtain for a given APD bias and the background and dark current. The CEA LETI HgCdTe APD technology, and a fine analysis of the gain curve characteristic are presented in [1] and won't be detailed here. The response time of the APD is also a key factor for a high frame rate FPA. This parameter has been evaluated in [2] and the results shows cut off frequencies in the GHz range. In this communication we report the performances of a SWIR APD FPA designed and fabricated by CEA LETI and SOFRADIR for astrophysical applications. This development was made in the frame of RAPID, a 4 years R&D project funded by the French FUI (Fond Unique Interministériel). This project involves industrial and academic partners from the field of advanced infrared focal plane arrays fabrication (SOFRADIR and CEA LETI) and of astronomical/defense institutes (IPAG, LAM, ONERA). The goal of this program is to develop a fast and low noise SWIR camera for astronomical fast applications like adaptive optics wavefront sensing and fringe tracking for astronomical interferometers [3]. The first batch of FPA's was based on liquid-phase epitaxy (LPE) grown photodiode arrays with 3 μm cut off wavelength. In order to get higher avalanche gain for a given photodiode reverse bias voltage, we have made a second batch with a cadmium composition leading to 3.3 μm cut off wavelength (λc). This paper described the read out circuit in the next section. The aim section III is to find the critical parameter that has to be measured to evaluate the signal to noise ratio (SNR) of an APD FPA. The main electro optical characteristics of an FPA based on 3.3μm cut off wavelength APDs are reported in "Rapid FPAs characterisation" section. The dark current evolution with temperature of a 3 μm FPA high and low APD bias is also detailed in this section.
NASA Technical Reports Server (NTRS)
Gallegos, Gregory L.; Odom, William R.; Guikema, James A.
1995-01-01
The study of higher plant growth and development in the microgravity (micro-g) environment continues to be a challenge. This is in part a result of the available flight qualified hardware with restrictive closed gas environments. This point is underscored by considering that gas exchange of seedlings grown in microgravity may be further limited owing to a thicker layer of water wicked onto the roots and to the absence of convective mixing. We hypothesized that seedlings grown under such conditions will experience greater hypoxia in microgravity than at Earth gravity, and thus produce greater stress ethylene. We compared flight and ground samples of sweet clover seedlings grown in the Fluid Processing Apparatus (FPA) during STS-57 and found them to contain extremely high levels of carbon dioxide (CO2) and stress ethylene. There were time dependent increases for both gases, and seedling growth was greatly inhibited. We repeated these experiments aboard STS-60 using modified chambers which increased, by fifty fold, the air available to the developing seedlings. Sweet clover seed germination and subsequent seedling growth to eight days within the FPA modified with a gas permeable membrane is not compromised by the microgravity environment.
[Blood coagulation and fibrinolysis in ischemic heart disease].
Sakamoto, T; Ogawa, H; Miyao, Y; Yasue, H
1994-01-01
Intracoronary thrombus formation has been thought to play an important role in the genesis of acute myocardial infarction an unstable angina. To examine whether the coagulation and fibrinolytic systems are altered in such ischemic heart diseases, the plasma levels of fibrinopeptide A (FPA) and plasminogen activator (PAI) were measured. The plasma level of FPA was increased in patients with variant angina as compared with those with stable exertional angina and there was a significant circadian variation in the plasma level of FPA in parallel with that of the frequency of the attacks with the peak level occurring from midnight to early morning in patients with variant angina. The plasma FPA level increased in patients with coronary spastic angina after the ischemic attack induced by hyperventilation. Furthermore, FPA was released into the coronary circulation after the anginal attack induced by intracoronary injection of acetylcholine. These findings suggest that the coronary artery spasm may induce thrombin generation and trigger thrombus formation in the coronary artery. On the other hand, the plasma level of PAI activity was higher in patients with unstable angina and coronary spastic angina than in those with stable exertional angina. Moreover, the PAI activity in patients with unstable angina decreased to the level in patients with stable exertional angina after the stabilization of their symptoms by drugs. Our findings suggest that the increased plasma PAI activity may reduce fibrinolytic activity and attenuate removal of the thrombus and may ultimately lead to acute myocardial infarction in some patients with unstable angina and coronary spastic angina.(ABSTRACT TRUNCATED AT 250 WORDS)
Landsat 9 OLI 2 focal plane subsystem: design, performance, and status
NASA Astrophysics Data System (ADS)
Malone, Kevin J.; Schrein, Ronald J.; Bradley, M. Scott; Irwin, Ronda; Berdanier, Barry; Donley, Eric
2017-09-01
The Landsat 9 mission will continue the legacy of Earth remote sensing that started in 1972. The Operational Land Imager 2 (OLI 2) is one of two instruments on the Landsat 9 satellite. The OLI 2 instrument is essentially a copy of the OLI instrument flying on Landsat 8. A key element of the OLI 2 instrument is the focal plane subsystem, or FPS, which consists of the focal plane array (FPA), the focal plane electronics (FPE) box, and low-thermal conductivity cables. This paper presents design details of the OLI 2 FPS. The FPA contains 14 critically-aligned focal plane modules (FPM). Each module contains 6 visible/near-IR (VNIR) detector arrays and three short-wave infrared (SWIR) arrays. A complex multi-spectral optical filter is contained in each module. Redundant pixels for each array provide exceptional operability. Spare detector modules from OLI were recharacterized after six years of storage. Radiometric test results are presented and compared with data recorded in 2010. Thermal, optical, mechanical and structural features of the FPA will be described. Special attention is paid to the thermal design of the FPA since thermal stability is crucial to ensuring low-noise and low-drift operation of the detectors which operate at -63°C. The OLI 2 FPE provides power, timing, and control to the focal plane modules. It also digitizes the video data and formats it for the solid-state recorder. Design improvements to the FPA-FPE cables will be discussed and characterization data will be presented. The paper will conclude with the status of the flight hardware assembly and testing.
A novel readout integrated circuit for ferroelectric FPA detector
NASA Astrophysics Data System (ADS)
Bai, Piji; Li, Lihua; Ji, Yulong; Zhang, Jia; Li, Min; Liang, Yan; Hu, Yanbo; Li, Songying
2017-11-01
Uncooled infrared detectors haves some advantages such as low cost light weight low power consumption, and superior reliability, compared with cryogenically cooled ones Ferroelectric uncooled focal plane array(FPA) are being developed for its AC response and its high reliability As a key part of the ferroelectric assembly the ROIC determines the performance of the assembly. A top-down design model for uncooled ferroelectric readout integrated circuit(ROIC) has been developed. Based on the optical thermal and electrical properties of the ferroelectric detector the RTIA readout integrated circuit is designed. The noise bandwidth of RTIA readout circuit has been developed and analyzed. A novel high gain amplifier, a high pass filter and a low pass filter circuits are designed on the ROIC. In order to improve the ferroelectric FPA package performance and decrease of package cost a temperature sensor is designed on the ROIC chip At last the novel RTIA ROIC is implemented on 0.6μm 2P3M CMOS silicon techniques. According to the experimental chip test results the temporal root mean square(RMS)noise voltage is about 1.4mV the sensitivity of the on chip temperature sensor is 0.6 mV/K from -40°C to 60°C the linearity performance of the ROIC chip is better than 99% Based on the 320×240 RTIA ROIC, a 320×240 infrared ferroelectric FPA is fabricated and tested. Test results shows that the 320×240 RTIA ROIC meets the demand of infrared ferroelectric FPA.
Mutekwa, V T; Gambiza, J
2017-08-01
In this literature review based paper we explored the concept of exclusion of local communities from accessing resources in forest protected areas (FPAs) in Zimbabwe. We discussed the colonial and post-colonial forms, causes and mechanisms of exclusion and their social, economic and ecological outcomes. We examined the range of powers embodied in and exercised through various mechanisms, processes and social relations and their impact on local communities' access to FPA resources and associated benefits along the historical trajectory of forest governance in Zimbabwe. Results showed that the forms and extent of exclusion changed over time in tandem with the shifting political and economic landscape. During the colonial period, it was total exclusion whereby people were evicted from forest land as well as being denied access to basic resources for their livelihoods. Local communities' access to low value FPA resources improved during the post-colonial period but access to high value resources like commercial timber as well as sharing income benefits derived from FPA commercial activities remained a pipe dream. Regulation, legitimation, force and markets constituted the mixture of the power elements that FPA governing authorities used to exclude local communities. These powers remained intact despite attempts at collaborative governance in the 1990s. However, from the year 2000, local communities expressed their dissatisfaction with the centralised exclusionary governance system by invading the FPAs rendering them ungovernable. There is therefore a need for policy reform within the FPA sector to improve the current dire situation. Copyright © 2017 Elsevier Ltd. All rights reserved.
Simultaneous multi-beam planar array IR (pair) spectroscopy
Elmore, Douglas L.; Rabolt, John F.; Tsao, Mei-Wei
2005-09-13
An apparatus and method capable of providing spatially multiplexed IR spectral information simultaneously in real-time for multiple samples or multiple spatial areas of one sample using IR absorption phenomena requires no moving parts or Fourier Transform during operation, and self-compensates for background spectra and degradation of component performance over time. IR spectral information and chemical analysis of the samples is determined by using one or more IR sources, sampling accessories for positioning the samples, optically dispersive elements, a focal plane array (FPA) arranged to detect the dispersed light beams, and a processor and display to control the FPA, and display an IR spectrograph. Fiber-optic coupling can be used to allow remote sensing. Portability, reliability, and ruggedness is enhanced due to the no-moving part construction. Applications include determining time-resolved orientation and characteristics of materials, including polymer monolayers. Orthogonal polarizers may be used to determine certain material characteristics.
Polarization Sensitive QWIP Thermal Imager
2000-03-01
array (FPA) with peak responsivity in the long-wave infrared ( LWIR ) spectral band near 9 µm. Polarization-dependent responsivity is achieved by...demonstrated in various combinations: MWIR/ LWIR (using rectangular grid gratings), MWIR/MWIR, and LWIR / LWIR . The FPA described here was fabricated with a...CCA supports the nonuniformity correction, global gain and level control, failed pixel substitution, dynamic range reduction, BIT status and serial
Multi-band infrared camera systems
NASA Astrophysics Data System (ADS)
Davis, Tim; Lang, Frank; Sinneger, Joe; Stabile, Paul; Tower, John
1994-12-01
The program resulted in an IR camera system that utilizes a unique MOS addressable focal plane array (FPA) with full TV resolution, electronic control capability, and windowing capability. Two systems were delivered, each with two different camera heads: a Stirling-cooled 3-5 micron band head and a liquid nitrogen-cooled, filter-wheel-based, 1.5-5 micron band head. Signal processing features include averaging up to 16 frames, flexible compensation modes, gain and offset control, and real-time dither. The primary digital interface is a Hewlett-Packard standard GPID (IEEE-488) port that is used to upload and download data. The FPA employs an X-Y addressed PtSi photodiode array, CMOS horizontal and vertical scan registers, horizontal signal line (HSL) buffers followed by a high-gain preamplifier and a depletion NMOS output amplifier. The 640 x 480 MOS X-Y addressed FPA has a high degree of flexibility in operational modes. By changing the digital data pattern applied to the vertical scan register, the FPA can be operated in either an interlaced or noninterlaced format. The thermal sensitivity performance of the second system's Stirling-cooled head was the best of the systems produced.
NASA Astrophysics Data System (ADS)
Gunapala, Sarath D.; Bandara, Sumith V.; Singh, Anjali; Liu, John K.; Rafol, S. B.; Luong, Edward M.; Mumolo, Jason M.; Tran, N. Q.; Vincent, John D.; Shott, C. A.; Long, James F.; LeVan, Paul D.
1999-07-01
An optimized long-wavelength two-color quantum well IR photodetector (QWIP) device structure has been designed. This device structure was grown on a three-inch semi- insulating GaAs substrate by molecule beam epitaxy (MBE). This wafer was processed into several 640 X 486 format monolithically integrated 8-9 and 14-15 micrometers two-color QWIP focal plane arrays (FPAs). These FPAs were then hybridized to 640 X 486 silicon CMOS readout multiplexers. A thinned FPA hybrid was integrated into a liquid helium cooled dewar to perform electrical and optical characterization and to demonstrate simultaneous two-color imagery. The 8-9 micrometers detectors in the FPA have shown background limited performance (BLIP) at 70 K operating temperature, at 300 K background with f/2 cold stop. The 14-15 micrometers detectors of the FPA have reached BLIP at 40 K operating temperature at the same background conditions. In this paper we discuss the performance of this long-wavelength dualband QWIP FPA in quantum efficiency, detectivity, noise equivalent temperature difference, uniformity, and operability.
NASA Astrophysics Data System (ADS)
Gunapala, S. D.; Bandara, S. V.; Singh, A.; Liu, J. K.; Rafol, S. B.
2000-01-01
We have designed and fabricated an optimized long-wavelength/very-long-wavelength two-color quantum well infrared photodetector (QWIP) device structure. The device structure was grown on a 3-in semi-insulating GaAs substrate by molecular beam epitaxy (MBE). The wafer was processed into several 640 x 486 format monolithically integrated 8-9 and 14-15 micrometers two-color (or dual wavelength) QWIP focal plane arrays (FPA's). These FPA's were then hybridized to 640 x 486 silicon CMOS readout multiplexers. A thinned (i.e., substrate removed) FPA hybrid was integrated into liquid helium cooled dewar for electrical and optical characterization and to demonstrate simultaneous two-color imagery. The 8-9 micrometers detectors in the FPA have shown background limited performance (BLIP) at 70 K operating temperature for 300 K background with f/2 cold stop. The 14-15 micrometers detectors of the SPA reach BLIP at 40 K operating temperature under the same background conditions. In this paper we discuss the performance of this long-wavelength dualband QWIP SPA in terms of quantum efficiency, detectivity, noise equivalent temperature difference (NE DELTA T), uniformity, and operability.
Strained-layer superlattice focal plane array having a planar structure
Kim, Jin K [Albuquerque, NM; Carroll, Malcolm S [Albuquerque, NM; Gin, Aaron [Albuquerque, NM; Marsh, Phillip F [Lowell, MA; Young, Erik W [Albuquerque, NM; Cich, Michael J [Albuquerque, NM
2010-07-13
An infrared focal plane array (FPA) is disclosed which utilizes a strained-layer superlattice (SLS) formed of alternating layers of InAs and In.sub.xGa.sub.1-xSb with 0.ltoreq.x.ltoreq.0.5 epitaxially grown on a GaSb substrate. The FPA avoids the use of a mesa structure to isolate each photodetector element and instead uses impurity-doped regions formed in or about each photodetector for electrical isolation. This results in a substantially-planar structure in which the SLS is unbroken across the entire width of a 2-D array of the photodetector elements which are capped with an epitaxially-grown passivation layer to reduce or eliminate surface recombination. The FPA has applications for use in the wavelength range of 3-25 .mu.m.
Strained layer superlattice focal plane array having a planar structure
Kim, Jin K; Carroll, Malcolm S; Gin, Aaron; Marsh, Phillip F; Young, Erik W; Cich, Michael J
2012-10-23
An infrared focal plane array (FPA) is disclosed which utilizes a strained-layer superlattice (SLS) formed of alternating layers of InAs and In.sub.xGa.sub.1-xSb with 0.ltoreq.x.ltoreq.0.5 epitaxially grown on a GaSb substrate. The FPA avoids the use of a mesa structure to isolate each photodetector element and instead uses impurity-doped regions formed in or about each photodetector for electrical isolation. This results in a substantially-planar structure in which the SLS is unbroken across the entire width of a 2-D array of the photodetector elements which are capped with an epitaxially-grown passivation layer to reduce or eliminate surface recombination. The FPA has applications for use in the wavelength range of 3-25 .mu.m.
78 FR 5256 - Annual Charges for Use of Government Lands
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-25
.... Information Collection Statement 67 B. Environmental Analysis 68 C. Regulatory Flexibility Act 69 D. Document.... Background 2. Section 10(e)(1) of the Federal Power Act (FPA) requires the hydropower licensees occupying... Amendment to Section 11.21 of the Regulations Under the Federal Power Act, 56 FPC 3860, at 3863 (1976). \\4...
NASA Astrophysics Data System (ADS)
DeYonker, Nathan J.; Halfen, DeWayne T.; Allen, Wesley D.; Ziurys, Lucy M.
2014-11-01
Six electronic states (X 4Σ-, A 4Π, B 4Δ, 2Φ, 2Δ, 2Σ+) of the vanadium monochloride cation (VCl+) are described using large basis set coupled cluster theory. For the two lowest quartet states (X 4Σ- and A 4Π), a focal point analysis (FPA) approach was used that conjoined a correlation-consistent family of basis sets up to aug-cc-pwCV5Z-DK with high-order coupled cluster theory through pentuple (CCSDTQP) excitations. FPA adiabatic excitation energies (T0) and spectroscopic constants (re, r0, Be, B0, bar De, He, ωe, v0, αe, ωexe) were extrapolated to the valence complete basis set Douglas-Kroll (DK) aug-cc-pV∞Z-DK CCSDT level of theory, and additional treatments accounted for higher-order valence electron correlation, core correlation, and spin-orbit coupling. Due to the delicate interplay between dynamical and static electronic correlation, single reference coupled cluster theory is able to provide the correct ground electronic state (X 4Σ-), while multireference configuration interaction theory cannot. Perturbations from the first- and second-order spin orbit coupling of low-lying states with quartet spin multiplicity reveal an immensely complex rotational spectrum relative to the isovalent species VO, VS, and TiCl. Computational data on the doublet manifold suggest that the lowest-lying doublet state (2Γ) has a Te of ˜11 200 cm-1. Overall, this study shows that laboratory and theoretical rotational spectroscopists must work more closely in tandem to better understand the bonding and structure of molecules containing transition metals.
Optical Imaging and Radiometric Modeling and Simulation
NASA Technical Reports Server (NTRS)
Ha, Kong Q.; Fitzmaurice, Michael W.; Moiser, Gary E.; Howard, Joseph M.; Le, Chi M.
2010-01-01
OPTOOL software is a general-purpose optical systems analysis tool that was developed to offer a solution to problems associated with computational programs written for the James Webb Space Telescope optical system. It integrates existing routines into coherent processes, and provides a structure with reusable capabilities that allow additional processes to be quickly developed and integrated. It has an extensive graphical user interface, which makes the tool more intuitive and friendly. OPTOOL is implemented using MATLAB with a Fourier optics-based approach for point spread function (PSF) calculations. It features parametric and Monte Carlo simulation capabilities, and uses a direct integration calculation to permit high spatial sampling of the PSF. Exit pupil optical path difference (OPD) maps can be generated using combinations of Zernike polynomials or shaped power spectral densities. The graphical user interface allows rapid creation of arbitrary pupil geometries, and entry of all other modeling parameters to support basic imaging and radiometric analyses. OPTOOL provides the capability to generate wavefront-error (WFE) maps for arbitrary grid sizes. These maps are 2D arrays containing digital sampled versions of functions ranging from Zernike polynomials to combination of sinusoidal wave functions in 2D, to functions generated from a spatial frequency power spectral distribution (PSD). It also can generate optical transfer functions (OTFs), which are incorporated into the PSF calculation. The user can specify radiometrics for the target and sky background, and key performance parameters for the instrument s focal plane array (FPA). This radiometric and detector model setup is fairly extensive, and includes parameters such as zodiacal background, thermal emission noise, read noise, and dark current. The setup also includes target spectral energy distribution as a function of wavelength for polychromatic sources, detector pixel size, and the FPA s charge diffusion modulation transfer function (MTF).
Type II superlattice technology for LWIR detectors
NASA Astrophysics Data System (ADS)
Klipstein, P. C.; Avnon, E.; Azulai, D.; Benny, Y.; Fraenkel, R.; Glozman, A.; Hojman, E.; Klin, O.; Krasovitsky, L.; Langof, L.; Lukomsky, I.; Nitzani, M.; Shtrichman, I.; Rappaport, N.; Snapi, N.; Weiss, E.; Tuito, A.
2016-05-01
SCD has developed a range of advanced infrared detectors based on III-V semiconductor heterostructures grown on GaSb. The XBn/XBp family of barrier detectors enables diffusion limited dark currents, comparable with MCT Rule-07, and high quantum efficiencies. This work describes some of the technical challenges that were overcome, and the ultimate performance that was finally achieved, for SCD's new 15 μm pitch "Pelican-D LW" type II superlattice (T2SL) XBp array detector. This detector is the first of SCD's line of high performance two dimensional arrays working in the LWIR spectral range, and was designed with a ~9.3 micron cut-off wavelength and a format of 640 x 512 pixels. It contains InAs/GaSb and InAs/AlSb T2SLs, engineered using k • p modeling of the energy bands and photo-response. The wafers are grown by molecular beam epitaxy and are fabricated into Focal Plane Array (FPA) detectors using standard FPA processes, including wet and dry etching, indium bump hybridization, under-fill, and back-side polishing. The FPA has a quantum efficiency of nearly 50%, and operates at 77 K and F/2.7 with background limited performance. The pixel operability of the FPA is above 99% and it exhibits a stable residual non uniformity (RNU) of better than 0.04% of the dynamic range. The FPA uses a new digital read-out integrated circuit (ROIC), and the complete detector closely follows the interfaces of SCD's MWIR Pelican-D detector. The Pelican- D LW detector is now in the final stages of qualification and transfer to production, with first prototypes already integrated into new electro-optical systems.
Szabó, István; Telekes, Hajnalka; Czakó, Gábor
2015-06-28
We develop a full-dimensional global analytical potential energy surface (PES) for the F(-) + CH3F reaction by fitting about 50 000 energy points obtained by an explicitly correlated composite method based on the second-order Møller-Plesset perturbation-F12 and coupled-cluster singles, doubles, and perturbative triples-F12a methods and the cc-pVnZ-F12 [n = D, T] basis sets. The PES accurately describes the (a) back-side attack Walden inversion mechanism involving the pre- and post-reaction (b) ion-dipole and (c) hydrogen-bonded complexes, the configuration-retaining (d) front-side attack and (e) double-inversion substitution pathways, as well as (f) the proton-abstraction channel. The benchmark quality relative energies of all the important stationary points are computed using the focal-point analysis (FPA) approach considering electron correlation up to coupled-cluster singles, doubles, triples, and perturbative quadruples method, extrapolation to the complete basis set limit, core-valence correlation, and scalar relativistic effects. The FPA classical(adiabatic) barrier heights of (a), (d), and (e) are -0.45(-0.61), 46.07(45.16), and 29.18(26.07) kcal mol(-1), respectively, the dissociation energies of (b) and (c) are 13.81(13.56) and 13.73(13.52) kcal mol(-1), respectively, and the endothermicity of (f) is 42.54(38.11) kcal mol(-1). Quasiclassical trajectory computations of cross sections, scattering (θ) and initial attack (α) angle distributions, as well as translational and internal energy distributions are performed for the F(-) + CH3F(v = 0) reaction using the new PES. Apart from low collision energies (Ecoll), the SN2 excitation function is nearly constant, the abstraction cross sections rapidly increase with Ecoll from a threshold of ∼40 kcal mol(-1), and retention trajectories via double inversion are found above Ecoll = ∼ 30 kcal mol(-1), and at Ecoll = ∼ 50 kcal mol(-1), the front-side attack cross sections start to increase very rapidly. At low Ecoll, the indirect mechanism dominates (mainly isotropic backward-forward symmetric θ distribution and translationally cold products) and significant long-range orientation effects (isotropic α distribution) and barrier recrossings are found. At higher Ecoll, the SN2 reaction mainly proceeds with direct rebound mechanism (backward scattering and hot product translation).
NASA Astrophysics Data System (ADS)
Szabó, István; Telekes, Hajnalka; Czakó, Gábor
2015-06-01
We develop a full-dimensional global analytical potential energy surface (PES) for the F- + CH3F reaction by fitting about 50 000 energy points obtained by an explicitly correlated composite method based on the second-order Møller-Plesset perturbation-F12 and coupled-cluster singles, doubles, and perturbative triples-F12a methods and the cc-pVnZ-F12 [n = D, T] basis sets. The PES accurately describes the (a) back-side attack Walden inversion mechanism involving the pre- and post-reaction (b) ion-dipole and (c) hydrogen-bonded complexes, the configuration-retaining (d) front-side attack and (e) double-inversion substitution pathways, as well as (f) the proton-abstraction channel. The benchmark quality relative energies of all the important stationary points are computed using the focal-point analysis (FPA) approach considering electron correlation up to coupled-cluster singles, doubles, triples, and perturbative quadruples method, extrapolation to the complete basis set limit, core-valence correlation, and scalar relativistic effects. The FPA classical(adiabatic) barrier heights of (a), (d), and (e) are -0.45(-0.61), 46.07(45.16), and 29.18(26.07) kcal mol-1, respectively, the dissociation energies of (b) and (c) are 13.81(13.56) and 13.73(13.52) kcal mol-1, respectively, and the endothermicity of (f) is 42.54(38.11) kcal mol-1. Quasiclassical trajectory computations of cross sections, scattering (θ) and initial attack (α) angle distributions, as well as translational and internal energy distributions are performed for the F- + CH3F(v = 0) reaction using the new PES. Apart from low collision energies (Ecoll), the SN2 excitation function is nearly constant, the abstraction cross sections rapidly increase with Ecoll from a threshold of ˜40 kcal mol-1, and retention trajectories via double inversion are found above Ecoll = ˜ 30 kcal mol-1, and at Ecoll = ˜ 50 kcal mol-1, the front-side attack cross sections start to increase very rapidly. At low Ecoll, the indirect mechanism dominates (mainly isotropic backward-forward symmetric θ distribution and translationally cold products) and significant long-range orientation effects (isotropic α distribution) and barrier recrossings are found. At higher Ecoll, the SN2 reaction mainly proceeds with direct rebound mechanism (backward scattering and hot product translation).
Fiber pulling apparatus modification
NASA Technical Reports Server (NTRS)
Smith, Guy A.; Workman, Gary L.
1992-01-01
A reduced gravity fiber pulling apparatus (FPA) was constructed in order to study the effects of gravity on glass fiber formation. The apparatus was specifically designed and built for use on NASA's KC-135 aircraft. Four flights have been completed to date during which E-glass fiber was successfully produced in simulated zero, high, and lunar gravity environments. In addition simulated lunar soil samples were tested for their fiber producing properties using the FPA.
Microwave spectrum, structure and dipole moment of 4-fluorophenylacetylene (4FPA)
NASA Astrophysics Data System (ADS)
Jang, Heesu; Ka, Soohyun; Dikkumbura, Asela S.; Peebles, Rebecca A.; Peebles, Sean A.; Oh, Jung Jin
2017-04-01
Using a chirped-pulse Fourier-transform microwave (CP-FTMW) spectrometer, a 6-18 GHz spectrum of 4-fluorophenylacetylene (4FPA) was measured and only a-type R-branch transitions were observed up to J = 9. Rotational constants and quartic centrifugal distortion constants for the normal isotopic species were determined based on Watson-S reduction: A = 5652.812(22) MHz, B = 966.92885(11) MHz, C = 825.67680(11) MHz, DJ = 0.01377(60) kHz, and DJK = 0.2468(61) kHz, with other three distortion constants fixed as DK = 0.6629 kHz, d1 = 2.386 Hz, and d2 = 0.989 Hz from ab initio results. For six kinds of carbon-13 isotopic species, 10-15 transitions were detected by a resonant cavity FTMW spectrometer in natural abundance, and rotational constants of each species were also determined by fitting transition frequencies. Gaseous molecular structures of 4FPA were derived via the least-squares fitting (r0) and substitution (rs) methods, and ab initio optimization (re). They were compared to the structures of benzene derivatives having fluorine and the acetylenic group as substituents. In addition, dipole moment component of 4FPA was also determined to be μa = μtotal = 0.8935(9) D from Stark effect measurements.
Lynch, Elizabeth
The FPA--formerly the Family Planning Association--celebrates its 75th anniversary this year. Since its inception, the association's remit has broadened from the provision of contraceptive advice to health education and help with sexual dysfunction. Before contraceptive services became available, women underwent multiple pregnancies. Until 1967, contraceptive advice was available only to married women. Family planning nurses now provide women with the contraceptive pill as well as injections and emergency contraception. The FPA provides termination of pregnancy and vasectomy services.
Not according to the high court, Professor Wolak
DOE Office of Scientific and Technical Information (OSTI.GOV)
Falk, Jonathan
2008-08-15
The FERC and its powers and actions related to ''just and reasonable'' prices are discussed in the aftermath of the California crisis. The decision in the case Morgan Stanley Capital Group Inc. v. Public Utility District No. 1 of Snohomish County et al. is addressed. The author concludes, FERC has an absolutely vital role to play in fulfilling its obligations under the FPA and in fostering a system that creates ''just and reasonable'' prices. It must certify markets that will be sufficiently competitive to allow market prices to become set. It must continually monitor those markets to ensure that competitivemore » conditions are met. It must enforce prohibitions against fraud and market manipulation. But if it does those things, it is entitled under the FPA to certify the prices thus generated as ''just and reasonable.'' And the justification is the long-run welfare of consumers, exactly the group the FPA was enacted to protect.« less
Keshinro, Oluremi Olufunke
2012-01-01
The objective of this study was to determine protein quality and hematological properties of infant diets formulated from local food materials. The food materials were obtained locally, fermented, and milled into flour. The flours were mixed as 70% popcorn and 30% African locust bean (FPA), 70% popcorn and 30% bambara groundnut (FPB), and 70% popcorn, 20% bambara groundnut, and 10% African locust bean (FPAB). Proximate analysis, protein quality, hematological properties, and anthropometric measurements of the animals fed with the formulations were investigated. The protein contents of the formulated diets were significantly higher than that of Cerelac (a commercial preparation) (15.75 ± 0.01 g/100 g) and ogi (traditional complementary food) (6.52 ± 0.31 g/100 g). The energy value of FPAB (464.94 ± 1.22 kcal) was higher than those of FPA (441.41 ± 3.05 kcal) and FPB (441.48 ± 3.05 kcal). The biological value (BV) of FPAB (60.20%) was the highest followed by FPB (44.24%) and FPA (41.15%); however, BV of the diets was higher than that of ogi (10.03%) but lower than that of Cerelac (70.43%). Net protein utilization (NPU) of the formulations was 41.16-60.20%, whereas true protein digestibility was 41.05-60.05%. Metabolizable energy (232.98 kcal) and digestible energy (83.69 kcal) of FPAB were the highest, whereas that of FPA had the lowest values. The protein digestibility values corrected for amino acid score of the diets (0.22-0.44) were lower than that of Cerelac (0.52), but higher than that of ogi (0.21). The growth patterns and hematological properties (packed cell volume, red blood cells, hemoglobin, mean corpuscular hemoglobin concentration, mean corpuscular hemoglobin, and mean corpuscular volume) of the formulated diets were higher than those of ogi, but lower than those of Cerelac. In conclusion, we established that the FPAB food sample was rated best in terms of protein quality over the other formulated diets. Therefore, a FPAB blend may be used as a substitute for ogi. PMID:23198016
Ijarotimi, Oluwole Steve; Keshinro, Oluremi Olufunke
2012-10-01
The objective of this study was to determine protein quality and hematological properties of infant diets formulated from local food materials. The food materials were obtained locally, fermented, and milled into flour. The flours were mixed as 70% popcorn and 30% African locust bean (FPA), 70% popcorn and 30% bambara groundnut (FPB), and 70% popcorn, 20% bambara groundnut, and 10% African locust bean (FPAB). Proximate analysis, protein quality, hematological properties, and anthropometric measurements of the animals fed with the formulations were investigated. The protein contents of the formulated diets were significantly higher than that of Cerelac (a commercial preparation) (15.75 ± 0.01 g/100 g) and ogi (traditional complementary food) (6.52 ± 0.31 g/100 g). The energy value of FPAB (464.94 ± 1.22 kcal) was higher than those of FPA (441.41 ± 3.05 kcal) and FPB (441.48 ± 3.05 kcal). The biological value (BV) of FPAB (60.20%) was the highest followed by FPB (44.24%) and FPA (41.15%); however, BV of the diets was higher than that of ogi (10.03%) but lower than that of Cerelac (70.43%). Net protein utilization (NPU) of the formulations was 41.16-60.20%, whereas true protein digestibility was 41.05-60.05%. Metabolizable energy (232.98 kcal) and digestible energy (83.69 kcal) of FPAB were the highest, whereas that of FPA had the lowest values. The protein digestibility values corrected for amino acid score of the diets (0.22-0.44) were lower than that of Cerelac (0.52), but higher than that of ogi (0.21). The growth patterns and hematological properties (packed cell volume, red blood cells, hemoglobin, mean corpuscular hemoglobin concentration, mean corpuscular hemoglobin, and mean corpuscular volume) of the formulated diets were higher than those of ogi, but lower than those of Cerelac. In conclusion, we established that the FPAB food sample was rated best in terms of protein quality over the other formulated diets. Therefore, a FPAB blend may be used as a substitute for ogi.
Staircase-scene-based nonuniformity correction in aerial point target detection systems.
Huo, Lijun; Zhou, Dabiao; Wang, Dejiang; Liu, Rang; He, Bin
2016-09-01
Focal-plane arrays (FPAs) are often interfered by heavy fixed-pattern noise, which severely degrades the detection rate and increases the false alarms in airborne point target detection systems. Thus, high-precision nonuniformity correction is an essential preprocessing step. In this paper, a new nonuniformity correction method is proposed based on a staircase scene. This correction method can compensate for the nonlinear response of the detector and calibrate the entire optical system with computational efficiency and implementation simplicity. Then, a proof-of-concept point target detection system is established with a long-wave Sofradir FPA. Finally, the local standard deviation of the corrected image and the signal-to-clutter ratio of the Airy disk of a Boeing B738 are measured to evaluate the performance of the proposed nonuniformity correction method. Our experimental results demonstrate that the proposed correction method achieves high-quality corrections.
Parametric study of two-body floating-point wave absorber
NASA Astrophysics Data System (ADS)
Amiri, Atena; Panahi, Roozbeh; Radfar, Soheil
2016-03-01
In this paper, we present a comprehensive numerical simulation of a point wave absorber in deep water. Analyses are performed in both the frequency and time domains. The converter is a two-body floating-point absorber (FPA) with one degree of freedom in the heave direction. Its two parts are connected by a linear mass-spring-damper system. The commercial ANSYS-AQWA software used in this study performs well in considering validations. The velocity potential is obtained by assuming incompressible and irrotational flow. As such, we investigated the effects of wave characteristics on energy conversion and device efficiency, including wave height and wave period, as well as the device diameter, draft, geometry, and damping coefficient. To validate the model, we compared our numerical results with those from similar experiments. Our study results can clearly help to maximize the converter's efficiency when considering specific conditions.
Jung, In-Keun; Park, Sang-Chul; Bin, Sung-Ah; Roh, Young Sup; Lee, John Hwan; Kim, Boo-Min
2016-03-01
The Maillard reaction has been well researched and used in the food industry and the fields of environmental science and organic chemistry. Here, we induced the Maillard reaction inside human hair and analyzed its effects by using Fourier transform infrared spectroscopy with a focal-plane array (FTIR-FPA) detector. We used arginine (A), glycine (G), and D-xylose (X) to generate the Maillard reaction by dissolving them in purified water and heating it to 150 °C. This label-free process generated a complex compound (named AGX after its ingredients) with a monomer structure, which was determined by using nuclear magnetic resonance (NMR) and FTIR-FPA. This compound was stable in hair and substantially increased its tensile strength. To our knowledge, we are the first to report the formation of this monomer in human hair, and our study provides insights into a new method that could be used to improve the condition of damaged or aging hair.
Chen, Hongzhang; Li, Yanjun; Xu, Fujian
2013-11-01
A self-designed novel solid-state fermentation (SSF) bioreactor named "gas double-dynamic solid-state fermentation bioreactor (GDSFB)" showed great success in processes for the production of several valuable products. For the present study, a simple GDSFB (2 L in volume) was designed to investigate the impact of exhaust time on SSF performance. Both air pressure and vent aperture significantly influenced the exhaust time. The production of cellulase by Penicillium decumbens JUA10 was studied in this bioreactor. When the vent aperture was maintained at 0.2 cm, the highest FPA activity of 17.2 IU/g dry solid-state medium was obtained at an air pressure of 0.2 MPa (gauge pressure). When the air pressure was maintained at 0.2 MPa, a vent aperture of 0.3 cm gave the highest FPA activity of 18.0 IU/g dry solid-state medium. Further analysis revealed that the exhaust time was a crucial indicator of good performance in GDSFB.
Vongsvivut, Jitraporn; Heraud, Philip; Gupta, Adarsha; Puri, Munish; McNaughton, Don; Barrow, Colin J
2013-10-21
The increase in polyunsaturated fatty acid (PUFA) consumption has prompted research into alternative resources other than fish oil. In this study, a new approach based on focal-plane-array Fourier transform infrared (FPA-FTIR) microspectroscopy and multivariate data analysis was developed for the characterisation of some marine microorganisms. Cell and lipid compositions in lipid-rich marine yeasts collected from the Australian coast were characterised in comparison to a commercially available PUFA-producing marine fungoid protist, thraustochytrid. Multivariate classification methods provided good discriminative accuracy evidenced from (i) separation of the yeasts from thraustochytrids and distinct spectral clusters among the yeasts that conformed well to their biological identities, and (ii) correct classification of yeasts from a totally independent set using cross-validation testing. The findings further indicated additional capability of the developed FPA-FTIR methodology, when combined with partial least squares regression (PLSR) analysis, for rapid monitoring of lipid production in one of the yeasts during the growth period, which was achieved at a high accuracy compared to the results obtained from the traditional lipid analysis based on gas chromatography. The developed FTIR-based approach when coupled to programmable withdrawal devices and a cytocentrifugation module would have strong potential as a novel online monitoring technology suited for bioprocessing applications and large-scale production.
LaWen Hollingsworth; James Menakis
2010-01-01
This project mapped wildland fire potential (WFP) for the conterminous United States by using the large fire simulation system developed for Fire Program Analysis (FPA) System. The large fire simulation system, referred to here as LFSim, consists of modules for weather generation, fire occurrence, fire suppression, and fire growth modeling. Weather was generated with...
Spectral and Polarimetric Imagery Collection Experiment (SPICE) Longwave Infrared Spectral Dataset
2014-09-01
radiance. Its 320x256 LWIR photovoltaic mercury cadmium telluride (PV MCT ) focal plane array (FPA) detectors are particularly sensitive to thermal...good as one can expect using the technology employed by Telops to manufacture these sensors, i.e., FPA of PV MCT detectors cooled to 65 K. We also...channeling in spectral data recorded by the Telops Hyper-Cam; the spectral ripple ( noise ), although embedded in the data, does not significantly change
Future Trends in MIcroelectronics: Up the Nano Creek
2006-06-01
developed focal plane arrays (FPA)3 in addition to emphasizing future development in UV-to-far infrared multicolor FPA detectors 5 for next generation... detectors ", IEEE J. Quantum Electronics 35, 1685 (1999). 3. P. Bois, E. Costard, X. Marcadet, and E. Herniou, "Development of quantum well infrared ...photodetector array", Infrared Phys. Technol. 44, 369 (2003). 5. M. N. Abedin, T. F. Refaat, J. M. Zawodny, et al., "Multicolor focal plane array detector
Report of mass communication Ceylon: October 1969-December 31, 1970.
1971-01-01
Experience with media usage by the FPA (Family Planning Association of Ceylon between October 1969 and December 1970 is summarized. During this time, the Association purchased 100-200 column inches each of contract advertising space in 26 newspapers. The press has published 268 press release, I.P.P.F., U.N., features and international press clipping in addition to specialized medical articles on family planning methods and 8 articles by FPA office-bearers. In January 1970; the Association launched local radio's first 5-minute daily commercial in Sinhala and Tamil. The program was repeated from April to July 1970. A series of 5 slides on family planning has been shown in movie theathers and more sets are being prepared for viewing. Posters have been used on buses and are currently on display on the National Railways project. Folders, leaflect, and poster calendars have been produced and used. Family Planning stickers have put up in 700 barber saloons. The FPA had stalls in the 1970 3-day National Exhibition at Batticaloa, the 4-day U.N. Poster Exhibition at Badulla, and the 2-week Ceylon Medical College Centenary Exhibition in Colombo. The Information Unit of FPA has answered 18, 541 written inquiries. A family planning communication us regularly dispatched to members of the Cabinet, government and opposition members of parliament, senators, chairmen of local bodies, and key trade union officials.
Vacuum packaging of InGaAs focal plane array with four-stage thermoelectric cooler
NASA Astrophysics Data System (ADS)
Mo, De-feng; Liu, Da-fu; Yang, Li-yi; Xu, Qin-fei; Li, Xue
2013-09-01
The InGaAs focal plane array (FPA) detectors, covering the near-infrared 1~2.4 μm wavelength range, have been developed for application in space-based spectroscopy of the Earth atmosphere. This paper shows an all-metal vacuum package design for area array InGaAs detector of 1024×64 pixels, and its architecture will be given. Four-stage thermoelectric cooler (TEC) is used to cool down the FPA chip. To acquire high heat dissipation for TEC's Joule-heat, tungsten copper (CuW80) and kovar (4J29) is used as motherboard and cavity material respectively which joined by brazing. The heat loss including conduction, convection and radiation is analyzed. Finite element model is established to analyze the temperature uniformity of the chip substrate which is made of aluminum nitride (AlN). The performance of The TEC with and without heat load in vacuum condition is tested. The results show that the heat load has little influence to current-voltage relationship of TEC. The temperature difference (ΔT) increases as the input current increases. A linear relationship exists between heat load and ΔT of the TEC. Theoretical analysis and calculation show that the heat loss of radiation and conduction is about 187 mW and 82 mW respectively. Considering the Joule-heat of readout circuit and the heat loss of radiation and conduction, the FPA for a 220 K operation at room temperature can be achieved. As the thickness of AlN chip substrate is thicker than 1 millimeter, the temperature difference can be less than 0.3 K.
Ogata, Kenji; Takamura, Norito; Tokunaga, Jin; Ikeda, Tetsuya; Setoguchi, Nao; Tanda, Kazuhiro; Yamasaki, Tetsuo; Nishio, Toyotaka; Kawai, Keiichi
2016-04-01
Flurbiprofen axetil (FPA) is an injection product and a prodrug of a non-steroidal anti-inflammatory drug (NSAID). After injection, it is rapidly hydrolyzed to the active form, flurbiprofen (FP). Since frequent injections of FPA can lead to abnormal physiology, an administration strategy is necessary to ensure there is enhancement of the analgesic efficiency of FP after a single dose and to reduce the total number of doses. FP strongly binds to site II of albumin, and thus the free (unbound) FP concentration is low. This study focused on 6-methoxy-2-naphthylacetic acid (6-MNA), the active metabolite of nabumetone (a prodrug of NSAID). We performed ultrafiltration experiments and pharmacokinetics analysis in rats to investigate whether the inhibitory effect of 6-MNA on FP binding to albumin increased the free FP concentration in vitro and in vivo. Results indicated that 6-MNA inhibited the binding of FP to albumin competitively. When 6-MNA was injected in rats, there was a significant increase in the free FP concentration and the area under concentration-time curve (AUC) calculated from the free FP concentration, while there was a significant decrease in the total (bound + free) FP concentration and the AUC calculated from the total FP concentration. These findings indicate that 6-MNA inhibits the protein binding of FP in vivo. This suggests that the frequency of FPA injections can be reduced when administered with nabumetone, as there is increase in the free FP concentration associated with pharmacological effect.
Cheng, Xiaofei; Zhang, Kai; Sun, Xiaojiang; Zhao, Changqing; Li, Hua; Zhao, Jie
2017-07-01
The objective was to analyze the compensatory effect of the pelvis and lower extremities on sagittal spinal malalignment in patients with pelvic incidence (PI) and lumbar lordosis (LL) mismatch. A series of parameters including PI, LL, PI-LL, thoracic kyphosis (TK), pelvic tilt (PT), sacral slope (SS), knee flexion angle (KFA), tibial obliquity angle (TOA), femoral obliquity angle (FOA), femur pelvis angle (FPA) and pelvic shift (PS) were measured. Patients with PI-LL mismatch were divided into pelvic retroversion group and pelvic retroposition group based on their PT and PS, and then the parameters were compared within the two groups and with the control group. All variables were significantly different when comparing the pelvic retroversion and retroposition group with the control group except for PI, FOA and PS in the pelvic retroversion group. The pelvic retroposition group had significantly greater value of PI-LL, PI, PT, KFA, FOA and PS and contribution ratio of FOA and PS, and smaller value of LL, TK and FPA and contribution ratio of PT, TOA and FPA compared with the pelvic retroversion group. Patients with lesser PI-LL mismatch rely more on hip extension to increase pelvic retroversion while those with greater PI-LL mismatch tend to add extra femoral obliquity. When compensating for larger PI-LL mismatch, the importance of hip extension is decreased and the effect of the knee and ankle joint becomes more important by providing greater femoral incline and relatively lesser ankle dorsiflexion respectively. Copyright © 2017 Elsevier B.V. All rights reserved.
A New Two-Color Infrared Photodetector Design Using INGAAS/INALAS Coupled Quantum Wells
1999-08-01
that spans the mid-wave infrared (MWIR) and the long-wave infrared ( LWIR ) atmospheric transmission windows of 3 to 5 and 8 to 12 µm, respectively...This leads to natural pixel registration in an FPA application. QWIP FPAs operating in two LWIR bands have been demonstrated,2 and, recently, the...Abstract unlimited Number of Pages 15 color FPA with simultaneous readout of an LWIR (9-µm peak) and an MWIR (5.1-µm peak) band was tested3 and shown to
2013-04-01
liquid nitrogen cooled mercury cadmium telluride ( MCT ) detector and compare their performance to a commercial FT-IR imaging instrument. We examine the...telluride ( MCT ) detector (InfraRed Associates, Stuart, FL), and in a second widefield imaging configuration, we employed a cooled focal plane array (FPA...experiment, a cooled focal plane array (FPA) was substituted for the bolometer. (b) A cooled single-element MCT detector is utilized with an adjustable
Study of a Wind Energy Conversion System in New Hampshire.
1981-08-01
Federal Jurisdiction Prior to PURPA ........ . 91 2) State Jurisdiction Prior to PURPA .... ....... 93 3) The Contemplated Effect of PURPA on the FERC’s...Jurisdictional Powers ..... ...... 94 (a) Definitions and Concepts of PURPA ... .. 95 (b) Analysis of Wheeling and Interconnection . 96 (i) FPA 9 210...Regarding Certain Interconnection and Wheeling ...... .. ........ 97 (c) PURPA § 210, Cogeneration and Small Power Production ...... ... ... .. 98 b
MTF Determination of SENTINEL-4 Detector Arrays
NASA Astrophysics Data System (ADS)
Reulke, R.; Sebastian, I.; Williges, C.; Hohn, R.
2017-05-01
The Institute for Optical Sensor Systems was involved in many international space projects in recent years. These include, for example, the fokal plane array (FPA) of the hyperspectral sensors ENMAP or Sentinel-4, but also the FPA for the high resolution FPA for Kompsat-3. An important requirement of the customer is the measurement of the detector MTF for different wavelengths. A measuring station under clean room conditions and evaluation algorithms was developed for these measurements. The measurement setup consist of a collimator with slit target in focus for illumination at infinity, a gimbal mounted detector facing an auxiliary lens in front, a halogen lamp with monochromator or filter, as well as optical and electrical ground support equipment. Different targets and therefore also different measurement and data evaluation opportunities are possible with this setup. Examples are slit, edge, pin hole but also a Siemens star. The article describes the measurement setup, the different measuring and evaluation procedures and exemplary results for Sentinel-4 detector.
Webb Instruments Perfected to Microscopic Levels
2014-06-20
Dressed in a cleanroom suit to prevent contamination, Optics Technician Jeff Gum aligns a replacement Focal Plane Assembly (FPA) with a powerful three-dimensional microscope at NASA's Goddard Space Flight Center in Greenbelt, Md. This FPA will be installed on the Near Infrared Camera (NIRCam) instrument, which has unique components that are individually tailored to see in a particular infrared wavelength range. By using the microscope, Gum ensures the FPA detectors are characterized and ready for installation onto NIRCam, the James Webb Space Telescope's primary imager that will see the light from the earliest stars and galaxies that formed in the universe. Credit: NASA/Goddard/Chris Gunn NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram
Modulation Transfer Function of Infrared Focal Plane Arrays
NASA Technical Reports Server (NTRS)
Gunapala, S. D.; Rafol, S. B.; Ting, D. Z.; Soibel, A.; Hill, C. J.; Khoshakhlagh, A.; Liu, J. K.; Mumolo, J. M.; Hoglund, L.; Luong, E. M.
2015-01-01
Modulation transfer function (MTF) is the ability of an imaging system to faithfully image a given object. The MTF of an imaging system quantifies the ability of the system to resolve or transfer spatial frequencies. In this presentation we will discuss the detail MTF measurements of 1024x1024 pixels mid -wavelength and long- wavelength quantum well infrared photodetector, and 320x256 pixels long- wavelength InAs/GaSb superlattice infrared focal plane arrays (FPAs). Long wavelength Complementary Barrier Infrared Detector (CBIRD) based on InAs/GaSb superlattice material is hybridized to recently designed and fabricated 320x256 pixel format ROIC. The n-type CBIRD was characterized in terms of performance and thermal stability. The experimentally measured NE delta T of the 8.8 micron cutoff n-CBIRD FPA was 18.6 mK with 300 K background and f/2 cold stop at 78K FPA operating temperature. The horizontal and vertical MTFs of this pixel fully delineated CBIRD FPA at Nyquist frequency are 49% and 52%, respectively.
The CHROMA focal plane array: a large-format, low-noise detector optimized for imaging spectroscopy
NASA Astrophysics Data System (ADS)
Demers, Richard T.; Bailey, Robert; Beletic, James W.; Bernd, Steve; Bhargava, Sidharth; Herring, Jason; Kobrin, Paul; Lee, Donald; Pan, Jianmei; Petersen, Anders; Piquette, Eric; Starr, Brian; Yamamoto, Matthew; Zandian, Majid
2013-09-01
The CHROMA (Configurable Hyperspectral Readout for Multiple Applications) is an advanced Focal Plane Array (FPA) designed for visible-infrared imaging spectroscopy. Using Teledyne's latest substrateremoved HgCdTe detector, the CHROMA FPA has very low dark current, low readout noise and high, stable quantum efficiency from the deep blue (390nm) to the cutoff wavelength. CHROMA has a pixel pitch of 30 microns and is available in array formats ranging from 320×480 to 1600×480 pixels. Users generally disperse spectra over the 480 pixel-length columns and image spatially over the n×160 pixellength rows, where n=2, 4, 8, 10. The CHROMA Readout Integrated Circuit (ROIC) has Correlated Double Sampling (CDS) in pixel and generates its own internal bias signals and clocks. This paper presents the measured performance of the CHROMA FPA with 2.5 micron cutoff wavelength including the characterization of noise versus pixel gain, power dissipation and quantum efficiency.
NASA Astrophysics Data System (ADS)
Ruffini, R.; Wang, Y.; Aimuratov, Y.; Barres de Almeida, U.; Becerra, L.; Bianco, C. L.; Chen, Y. C.; Karlica, M.; Kovacevic, M.; Li, L.; Melon Fuksman, J. D.; Moradi, R.; Muccino, M.; Penacchioni, A. V.; Pisani, G. B.; Primorac, D.; Rueda, J. A.; Shakeri, S.; Vereshchagin, G. V.; Xue, S.-S.
2018-01-01
We analyze the early X-ray flares in the GRB “flare–plateau–afterglow” (FPA) phase observed by Swift-XRT. The FPA occurs only in one of the seven GRB subclasses: the binary-driven hypernovae (BdHNe). This subclass consists of long GRBs with a carbon–oxygen core and a neutron star (NS) binary companion as progenitors. The hypercritical accretion of the supernova (SN) ejecta onto the NS can lead to the gravitational collapse of the NS into a black hole. Consequently, one can observe a GRB emission with isotropic energy {E}{iso}≳ {10}52 erg, as well as the associated GeV emission and the FPA phase. Previous work had shown that gamma-ray spikes in the prompt emission occur at ∼ {10}15{--}{10}17 cm with Lorentz Gamma factors {{Γ }}∼ {10}2{--}{10}3. Using a novel data analysis, we show that the time of occurrence, duration, luminosity, and total energy of the X-ray flares correlate with E iso. A crucial feature is the observation of thermal emission in the X-ray flares that we show occurs at radii ∼1012 cm with {{Γ }}≲ 4. These model-independent observations cannot be explained by the “fireball” model, which postulates synchrotron and inverse-Compton radiation from a single ultrarelativistic jetted emission extending from the prompt to the late afterglow and GeV emission phases. We show that in BdHNe a collision between the GRB and the SN ejecta occurs at ≃1010 cm, reaching transparency at ∼1012 cm with {{Γ }}≲ 4. The agreement between the thermal emission observations and these theoretically derived values validates our model and opens the possibility of testing each BdHN episode with the corresponding Lorentz Gamma factor.
The University of Florida's next-generation cryogenic infrared focal plane array controller system
NASA Astrophysics Data System (ADS)
Raines, Steven N.; Boreman, Glenn D.; Eikenberry, Stephen S.; Bandyopadhyay, Reba M.; Quijano, Ismael
2008-07-01
The Infrared Instrumentation Group at the University of Florida has substantial experience building IR focal plane array (FPA) controllers and seamlessly integrating them into the instruments that it builds for 8-meter class observatories, including writing device drivers for UNIX-based computer systems. We report on a design study to investigate implementing an ASIC from Teledyne Imaging Systems (TIS) into our IR FPA controller while simultaneously replacing TIS's interface card with one that eliminates the requirement for a Windows-OS computer within the instrument's control system.
Quantum Well and Quantum Dot Modeling for Advanced Infrared Detectors and Focal Plane Arrays
NASA Technical Reports Server (NTRS)
Ting, David; Gunapala, S. D.; Bandara, S. V.; Hill, C. J.
2006-01-01
This viewgraph presentation reviews the modeling of Quantum Well Infrared Detectors (QWIP) and Quantum Dot Infrared Detectors (QDIP) in the development of Focal Plane Arrays (FPA). The QWIP Detector being developed is a dual band detector. It is capable of running on two bands Long-Wave Infrared (LWIR) and Medium Wavelength Infrared (MWIR). The same large-format dual-band FPA technology can be applied to Quantum Dot Infrared Photodetector (QDIP) with no modification, once QDIP exceeds QWIP in single device performance. Details of the devices are reviewed.
Large-format InGaAs focal plane arrays for SWIR imaging
NASA Astrophysics Data System (ADS)
Hood, Andrew D.; MacDougal, Michael H.; Manzo, Juan; Follman, David; Geske, Jonathan C.
2012-06-01
FLIR Electro Optical Components will present our latest developments in large InGaAs focal plane arrays, which are used for low light level imaging in the short wavelength infrared (SWIR) regime. FLIR will present imaging from their latest small pitch (15 μm) focal plane arrays in VGA and High Definition (HD) formats. FLIR will present characterization of the FPA including dark current measurements as well as the use of correlated double sampling to reduce read noise. FLIR will show imagery as well as FPA-level characterization data.
Color camera computed tomography imaging spectrometer for improved spatial-spectral image accuracy
NASA Technical Reports Server (NTRS)
Wilson, Daniel W. (Inventor); Bearman, Gregory H. (Inventor); Johnson, William R. (Inventor)
2011-01-01
Computed tomography imaging spectrometers ("CTIS"s) having color focal plane array detectors are provided. The color FPA detector may comprise a digital color camera including a digital image sensor, such as a Foveon X3.RTM. digital image sensor or a Bayer color filter mosaic. In another embodiment, the CTIS includes a pattern imposed either directly on the object scene being imaged or at the field stop aperture. The use of a color FPA detector and the pattern improves the accuracy of the captured spatial and spectral information.
Modulate chopper technique used in pyroelectric uncooled focal plane array thermal imager
NASA Astrophysics Data System (ADS)
He, Yuqing; Jin, Weiqi; Liu, Guangrong; Gao, Zhiyun; Wang, Xia; Wang, Lingxue
2002-09-01
Pyroelectric uncooled focal plane array (FPA) thermal imager has the advantages of low cost, small size, high responsibility and can work under room temperature, so it has great progress in recent years. As a matched technique, the modulate chopper has become one of the key techniques in uncooled FPA thermal imaging system. Now the Archimedes spiral cord chopper technique is mostly used. When it works, the chopper pushing scans the detector's pixel array, thus makes the pixels being exposed continuously. This paper simulates the shape of this kind of chopper, analyses the exposure time of the detector's every pixel, and also analyses the whole detector pixels' exposure sequence. From the analysis we can get the results: the parameter of Archimedes spiral cord, the detector's thermal time constant, the detector's geometrical dimension, the relative position of the detector to the chopper's spiral cord are the system's important parameters, they will affect the chopper's exposure efficiency and uniformity. We should design the chopper's relevant parameter according to the practical request to achieve the chopper's appropriate structure.
High-resolution panoramic images with megapixel MWIR FPA
NASA Astrophysics Data System (ADS)
Leboucher, Vincent; Aubry, Gilles
2014-06-01
In the continuity of its current strategy, HGH maintains a deep effort in developing its most recent product family: the infrared (IR) panoramic 360-degree surveillance sensors. During the last two years, HGH optimized its prototype Middle Wave IR (MWIR) panoramic sensor IR Revolution 360 HD that gave birth to Spynel-S product. Various test campaigns proved its excellent image quality. Cyclope, the software associated with Spynel, benefitted from recent image processing improvements and new functionalities such as target geolocalization, long range sensor slue to cue and facilitated forensics analysis. In the frame of the PANORAMIR project sustained by the DGA (Délégation Générale de l'Armement), HGH designed a new extra large resolution sensor including a MWIR megapixel Focal Plane Array (FPA) detector (1280×1024 pixels). This new sensor is called Spynel-X. It provides outstanding resolution 360-degree images (with more than 100 Mpixels). The mechanical frame of Spynel (-S and -X) was designed with the collaboration of an industrial design agency. Spynel got the "Observeur du Design 2013" label.
DOE Office of Scientific and Technical Information (OSTI.GOV)
DeYonker, Nathan J., E-mail: ndyonker@memphis.edu; Halfen, DeWayne T.; Ziurys, Lucy M.
Six electronic states (X {sup 4}Σ{sup −}, A {sup 4}Π, B {sup 4}Δ, {sup 2}Φ, {sup 2}Δ, {sup 2}Σ{sup +}) of the vanadium monochloride cation (VCl{sup +}) are described using large basis set coupled cluster theory. For the two lowest quartet states (X {sup 4}Σ{sup −} and A {sup 4}Π), a focal point analysis (FPA) approach was used that conjoined a correlation-consistent family of basis sets up to aug-cc-pwCV5Z-DK with high-order coupled cluster theory through pentuple (CCSDTQP) excitations. FPA adiabatic excitation energies (T{sub 0}) and spectroscopic constants (r{sub e}, r{sub 0}, B{sub e}, B{sub 0}, D{sup ¯}{sub e}, H{sub e},more » ω{sub e}, v{sub 0}, α{sub e}, ω{sub e}x{sub e}) were extrapolated to the valence complete basis set Douglas-Kroll (DK) aug-cc-pV∞Z-DK CCSDT level of theory, and additional treatments accounted for higher-order valence electron correlation, core correlation, and spin-orbit coupling. Due to the delicate interplay between dynamical and static electronic correlation, single reference coupled cluster theory is able to provide the correct ground electronic state (X {sup 4}Σ{sup −}), while multireference configuration interaction theory cannot. Perturbations from the first- and second-order spin orbit coupling of low-lying states with quartet spin multiplicity reveal an immensely complex rotational spectrum relative to the isovalent species VO, VS, and TiCl. Computational data on the doublet manifold suggest that the lowest-lying doublet state ({sup 2}Γ) has a T{sub e} of ∼11 200 cm{sup −1}. Overall, this study shows that laboratory and theoretical rotational spectroscopists must work more closely in tandem to better understand the bonding and structure of molecules containing transition metals.« less
Can IR scene projectors reduce total system cost?
NASA Astrophysics Data System (ADS)
Ginn, Robert; Solomon, Steven
2006-05-01
There is an incredible amount of system engineering involved in turning the typical infrared system needs of probability of detection, probability of identification, and probability of false alarm into focal plane array (FPA) requirements of noise equivalent irradiance (NEI), modulation transfer function (MTF), fixed pattern noise (FPN), and defective pixels. Unfortunately, there are no analytic solutions to this problem so many approximations and plenty of "seat of the pants" engineering is employed. This leads to conservative specifications, which needlessly drive up system costs by increasing system engineering costs, reducing FPA yields, increasing test costs, increasing rework and the never ending renegotiation of requirements in an effort to rein in costs. These issues do not include the added complexity to the FPA factory manager of trying to meet varied, and changing, requirements for similar products because different customers have made different approximations and flown down different specifications. Scene generation technology may well be mature and cost effective enough to generate considerable overall savings for FPA based systems. We will compare the costs and capabilities of various existing scene generation systems and estimate the potential savings if implemented at several locations in the IR system fabrication cycle. The costs of implementing this new testing methodology will be compared to the probable savings in systems engineering, test, rework, yield improvement and others. The diverse requirements and techniques required for testing missile warning systems, missile seekers, and FLIRs will be defined. Last, we will discuss both the hardware and software requirements necessary to meet the new test paradigm and discuss additional cost improvements related to the incorporation of these technologies.
Maleckis, Kaspars; Anttila, Eric; Aylward, Paul; Poulson, William; Desyatova, Anastasia; MacTaggart, Jason; Kamenskiy, Alexey
2018-01-01
Endovascular stenting has matured into a commonly used treatment for peripheral arterial disease (PAD) due to its minimally invasive nature and associated reductions in short-termmorbidity and mortality. The mechanical properties of the superelastic Nitinol alloy have played a major role in the explosion of peripheral artery stenting, with modern stents demonstrating reasonable resilience and durability. Yet in the superficial femoral and popliteal arteries, even the newest generation Nitinol stents continue to demonstrate clinical outcomes that leave significant room for improvement. Restenosis and progression of native arterial disease often lead to recurrence of symptoms and reinterventions that increase morbidity and health care expenditures. One of the main factors thought to be associated with stent failure in the femoropopliteal artery (FPA) is the unique and highly dynamic mechanical environment of the lower limb. Clinical and experimental data demonstrate that the FPA undergoes significant deformations with limb flexion. It is hypothesized that the inability of many existing stent designs to conform to these deformations likely plays a role in reconstruction failure, as repetitive movements of the leg and thigh combine with mechanical mismatch between the artery and the stent and result in mechanical damage to both the artery and the stent. In this review we will identify challenges and provide a mechanical perspective of FPA stenting, and then discuss current research directions with promise to provide a better understanding of Nitinol, specific features of stent design, and improved characterization of the biomechanical environment of the FPA to facilitate development of better stents for patients with PAD. PMID:29470746
NASA Astrophysics Data System (ADS)
Roy, Sunil K.; Kumar, M. Ravi; Davuluri, Srinagesh
2017-08-01
This study presents 106 splitting and 40 null measurements of source side anisotropy in subduction zones, utilizing direct S waves registered at two stations sited on the Indian continent, which show null shear wave splitting measurements for SKS phases. Our results suggest that trench-parallel anisotropy is dominant beneath the Philippines, Mariana, Izu-Bonin, and edge of the Java slab, while plate motion-parallel anisotropy is observed beneath the Solomon, Aegean, Japan, and Java slabs. Results from Kuril and Aleutian regions reveal trench-oblique anisotropy. We chose to interpret these observations primarily in terms of mantle flow beneath a subduction zone. While the two-dimensional (2-D) slab entrained flow model offers a simple explanation for trench-normal fast polarization azimuths (FPA), the trench-parallel FPA can be reconciled by extension due to slab rollback. The model that invokes age of the subducting lithosphere can explain anisotropy in the subslab, derived from rays recorded at the updip stations. However, when downdip stations are used, contributions from the slab and supraslab need to be considered. In Japan, anisotropy in the subslab mantle shallower than 300 km might be associated with trench-parallel mantle flow resulting in the alignment of FPA in the same direction. Anisotropy in the deeper part, above the transition zone, is probably associated with 2-D flow resulting in trench-normal FPA. Anisotropy in the Mariana Trench might be associated with trench-parallel mantle flow in the supraslab region, with similar deformation in the upper mantle and the transition zone.
Maleckis, Kaspars; Anttila, Eric; Aylward, Paul; Poulson, William; Desyatova, Anastasia; MacTaggart, Jason; Kamenskiy, Alexey
2018-05-01
Endovascular stenting has matured into a commonly used treatment for peripheral arterial disease (PAD) due to its minimally invasive nature and associated reductions in short-term morbidity and mortality. The mechanical properties of the superelastic Nitinol alloy have played a major role in the explosion of peripheral artery stenting, with modern stents demonstrating reasonable resilience and durability. Yet in the superficial femoral and popliteal arteries, even the newest generation Nitinol stents continue to demonstrate clinical outcomes that leave significant room for improvement. Restenosis and progression of native arterial disease often lead to recurrence of symptoms and reinterventions that increase morbidity and health care expenditures. One of the main factors thought to be associated with stent failure in the femoropopliteal artery (FPA) is the unique and highly dynamic mechanical environment of the lower limb. Clinical and experimental data demonstrate that the FPA undergoes significant deformations with limb flexion. It is hypothesized that the inability of many existing stent designs to conform to these deformations likely plays a role in reconstruction failure, as repetitive movements of the leg and thigh combine with mechanical mismatch between the artery and the stent and result in mechanical damage to both the artery and the stent. In this review we will identify challenges and provide a mechanical perspective of FPA stenting, and then discuss current research directions with promise to provide a better understanding of Nitinol, specific features of stent design, and improved characterization of the biomechanical environment of the FPA to facilitate development of better stents for patients with PAD.
High-performance IR detector modules
NASA Astrophysics Data System (ADS)
Wendler, Joachim; Cabanski, Wolfgang; Rühlich, Ingo; Ziegler, Johann
2004-02-01
The 3rd generation of infrared (IR) detection modules is expected to provide higher video resolution, advanced functions like multi band or multi color capability, higher frame rates, and better thermal resolution. AIM has developed staring and linear high performance focal plane arrays (FPA) integrated into detector/dewar cooler assemblies (IDCA). Linear FPA"s support high resolution formats such as 1920 x 1152 (HDTV), 1280 x 960, or 1536 x 1152. Standard format for staring FPA"s is 640 x 512. In this configuration, QEIP devices sensitive in the 8 10 µm band as well as MCT devices sensitive in the 3.4 5.0 µm band are available. A 256 x 256 high speed detection module allows a full frame rate >800 Hz. Especially usability of long wavelength devices in high performance FLIR systems does not only depend on the classical electrooptical performance parameters such as NEDT, detectivity, and response homogeneity, but are mainly characterized by the stability of the correction coefficients used for image correction. The FPA"s are available in suited integrated detector/dewar cooler assemblies. The linear cooling engines are designed for maximum stability of the focal plane temperature, low operating temperatures down to 60K, high MTTF lifetimes of 6000h and above even under high ambient temperature conditions. The IDCA"s are equipped with AIM standard or custom specific command and control electronics (CCE) providing a well defined interface to the system electronics. Video output signals are provided as 14 bit digital data rates up to 80 MHz for the high speed devices.
Effect of heparin bonding on catheter-induced fibrin formation and platelet activation.
Nichols, A B; Owen, J; Grossman, B A; Marcella, J J; Fleisher, L N; Lee, M M
1984-11-01
Pathologic and experimental evidence indicates that platelet activation and fibrin formation contribute to the pathogenesis of angina pectoris, coronary vasospasm and myocardial infarction. Detection of localized intravascular platelet activation and fibrin formation in vivo by selective blood sampling requires catheters that do not induce coagulation ex vivo. We studied the effect of heparin bonding of catheter surfaces on activation of the coagulation system by cardiovascular catheters. Woven Dacron, polyvinylchloride, and polyurethane catheters were tested and compared with identical catheters with heparin-bonded surfaces in 47 patients undergoing percutaneous cardiac catheterization. Platelet activation was measured by radioimmunoassay of plasma platelet factor 4 (PF4), beta-thromboglobulin (BTG), and thromboxane B2 (TXB2) in blood samples withdrawn through catheters, and fibrin formation was assessed by determination of fibrinopeptide A (FPA) levels. In blood samples collected through conventional catheters, FPA, PF4, BTG, and TXB2 levels were markedly elevated; blood sampling through heparin-bonded catheters had no significant effect on FPA, PF4, BTG, or TXB2 levels. Scanning electron microscopy disclosed extensive platelet aggregates and fibrin strands adherent to the surface of conventional catheters but not to heparin-bonded catheter surfaces. This study demonstrates that (1) collection of blood samples through cardiovascular catheters causes artifactual elevation of FPA, PF4, BTG, and TXB2 levels, and (2) heparin-bonded catheter surfaces effectively prevent catheter-induced platelet alpha-granule release and fibrin formation on catheter surfaces. Heparin-bonded catheters will facilitate investigation of the role of intravascular coagulation in coronary artery disease by eliminating catheter-induced fibrin formation and platelet activation.
NASA Technical Reports Server (NTRS)
Vural, Kadri; Blessinger, Michael; Chen, Jenkon; Kleinhans, William
1989-01-01
Researchers developed a HgCdTe 256x256 focal plane array (FPA) which operates in the 1 to 5 micron band. This is presently the largest demonstrated HgCdTe FPA. The detector material is HgCdTe on sapphire (PACE-1 technology) which has a low thermal expansion mismatch with silicon. The multiplexer is a CMOS FET-switch device processed through a commercial silicon foundry. The multiplexer input is direct injection and the charge capacity is about 2 times 10 to the 7th power electrons. The kTC limited read noise is 400 electrons. Researchers demonstrated high background imaging using the device. The broadband quantum efficiency is measured to be 59 percent. Dark currents less than 0.1 pA were measured at 77 K for detectors processed on PACE-1 material with 4.9 microns cutoff. The dark currents decrease as the temperature is lowered, and researchers are presently studying the T less than 77 K characteristics. The interconnect yield is greater than 95 percent. The devices are available for astronomical applications.
Low-SWAP Lidar Instrument for Arctic Ice Sheet Mass Balance Monitoring Final Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Williams, George; Barsic, David
To meet the need to obtain statistically significant data in the North Slope of Alaska (NSA) in support of climate models, Voxtel is developing an nmanned-aircraft-system (UAS)-optimized lidar focal plane array (FPA) and lidar instrument design that integrates the most recent developments in optics, electronics, and computing. Bound by the size, weight, and power (SWAP) budget of low altitude/long endurance (LALE) small UAS (SUAS) platforms—a design tradeoff study was conducted. The class of SUAS considered typically: operates at altitudes between 150 meters and 2,000 meters; accommodates payloads weighing less than 5 kg; encompasses no more than 4,000 cm3 of space;more » and consumes no more than 50 watts of power. To address the SWAP constraints, a lowpower standalone strap-down (gimbal-less) lidar was developed based on single-photon-counting silicon avalanche photodiodes. To reduce SWAP, a lidar FPA design capable of simultaneous imaging and lidar was developed. The 532-nm-optimized FPA modular design was developed for easy integration, as a lidar payload, in any of a variety of SUAS platforms.« less
Xia, Ying; Yang, Lirong; Xia, Liming
2018-06-16
The industrial application of Trichoderma reesei has been greatly limited by insufficient β-glucosidase activity in its cellulase system. In this study, a novel β-glucosidase expression cassette was constructed and integrated at the target site in T. reesei ZU-02, which achieved the overexpression of β-glucosidase gene and in situ disruption of the cellulase transcriptional repressor ACE1. The resulting transformants showed significant increase in both β-glucosidase activity (BGA) and filter paper activity (FPA). The BGA and FPA increased to 25.13 IU/mL and 20.06 FPU/mL, respectively, 167- and 2.45-fold higher than that of the host strain. Meanwhile, the obtained cellulase system exhibited improved ratio of BGA to FPA, leading to better synergistic effect between cellulase components. Furthermore, submerged fermentation of the transformant was established in 50 m 3 fermenter yielding 112.2 IU/mL β-glucosidase and 89.76 FPU/mL total cellulase. The newly constructed T. reesei transformant achieved improved hydrolysis yield (90.6%) with reduced enzyme loading (15 FPU/g substrate).
Correction method for stripe nonuniformity.
Qian, Weixian; Chen, Qian; Gu, Guohua; Guan, Zhiqiang
2010-04-01
Stripe nonuniformity is very typical in line infrared focal plane arrays (IR-FPA) and uncooled staring IR-FPA. In this paper, the mechanism of the stripe nonuniformity is analyzed, and the gray-scale co-occurrence matrix theory and optimization theory are studied. Through these efforts, the stripe nonuniformity correction problem is translated into the optimization problem. The goal of the optimization is to find the minimal energy of the image's line gradient. After solving the constrained nonlinear optimization equation, the parameters of the stripe nonuniformity correction are obtained and the stripe nonuniformity correction is achieved. The experiments indicate that this algorithm is effective and efficient.
Infrared Detector Activities at NASA Langley Research Center
NASA Technical Reports Server (NTRS)
Abedin, M. N.; Refaat, T. F.; Sulima, O. V.; Amzajerdian, F.
2008-01-01
Infrared detector development and characterization at NASA Langley Research Center will be reviewed. These detectors were intended for ground, airborne, and space borne remote sensing applications. Discussion will be focused on recently developed single-element infrared detector and future development of near-infrared focal plane arrays (FPA). The FPA will be applied to next generation space-based instruments. These activities are based on phototransistor and avalanche photodiode technologies, which offer high internal gain and relatively low noise-equivalent-power. These novel devices will improve the sensitivity of active remote sensing instruments while eliminating the need for a high power laser transmitter.
Agnesi, Filippo; Tye, Susannah J.; Bledsoe, Jonathan M.; Griessenauer, Christoph J.; Kimble, Christopher J.; Sieck, Gary C.; Bennet, Kevin E.; Garris, Paul A.; Blaha, Charles D.; Lee, Kendall H.
2009-01-01
Object In a companion study, the authors describe the development of a new instrument named the Wireless Instantaneous Neurotransmitter Concentration System (WINCS), which couples digital telemetry with fast-scan cyclic voltammetry (FSCV) to measure extracellular concentrations of dopamine. In the present study, the authors describe the extended capability of the WINCS to use fixed potential amperometry (FPA) to measure extracellular concentrations of dopamine, as well as glutamate and adenosine. Compared with other electrochemical techniques such as FSCV or high-speed chronoamperometry, FPA offers superior temporal resolution and, in combination with enzyme-linked biosensors, the potential to monitor nonelectroactive analytes in real time. Methods The WINCS design incorporated a transimpedance amplifier with associated analog circuitry for FPA; a microprocessor; a Bluetooth transceiver; and a single, battery-powered, multilayer, printed circuit board. The WINCS was tested with 3 distinct recording electrodes: 1) a carbon-fiber microelectrode (CFM) to measure dopamine; 2) a glutamate oxidase enzyme-linked electrode to measure glutamate; and 3) a multiple enzyme-linked electrode (adenosine deaminase, nucleoside phosphorylase, and xanthine oxidase) to measure adenosine. Proof-of-principle analyses included noise assessments and in vitro and in vivo measurements that were compared with similar analyses by using a commercial hardwired electrochemical system (EA161 Picostat, eDAQ; Pty Ltd). In urethane-anesthetized rats, dopamine release was monitored in the striatum following deep brain stimulation (DBS) of ascending dopaminergic fibers in the medial forebrain bundle (MFB). In separate rat experiments, DBS-evoked adenosine release was monitored in the ventrolateral thalamus. To test the WINCS in an operating room setting resembling human neurosurgery, cortical glutamate release in response to motor cortex stimulation (MCS) was monitored using a large-mammal animal model, the pig. Results The WINCS, which is designed in compliance with FDA-recognized consensus standards for medical electrical device safety, successfully measured dopamine, glutamate, and adenosine, both in vitro and in vivo. The WINCS detected striatal dopamine release at the implanted CFM during DBS of the MFB. The DBS-evoked adenosine release in the rat thalamus and MCS-evoked glutamate release in the pig cortex were also successfully measured. Overall, in vitro and in vivo testing demonstrated signals comparable to a commercial hardwired electrochemical system for FPA. Conclusions By incorporating FPA, the chemical repertoire of WINCS-measurable neurotransmitters is expanded to include glutamate and other nonelectroactive species for which the evolving field of enzyme-linked biosensors exists. Because many neurotransmitters are not electrochemically active, FPA in combination with enzyme-linked microelectrodes represents a powerful intraoperative tool for rapid and selective neurochemical sampling in important anatomical targets during functional neurosurgery. PMID:19425899
Agnesi, Filippo; Tye, Susannah J; Bledsoe, Jonathan M; Griessenauer, Christoph J; Kimble, Christopher J; Sieck, Gary C; Bennet, Kevin E; Garris, Paul A; Blaha, Charles D; Lee, Kendall H
2009-10-01
In a companion study, the authors describe the development of a new instrument named the Wireless Instantaneous Neurotransmitter Concentration System (WINCS), which couples digital telemetry with fast-scan cyclic voltammetry (FSCV) to measure extracellular concentrations of dopamine. In the present study, the authors describe the extended capability of the WINCS to use fixed potential amperometry (FPA) to measure extracellular concentrations of dopamine, as well as glutamate and adenosine. Compared with other electrochemical techniques such as FSCV or high-speed chronoamperometry, FPA offers superior temporal resolution and, in combination with enzyme-linked biosensors, the potential to monitor nonelectroactive analytes in real time. The WINCS design incorporated a transimpedance amplifier with associated analog circuitry for FPA; a microprocessor; a Bluetooth transceiver; and a single, battery-powered, multilayer, printed circuit board. The WINCS was tested with 3 distinct recording electrodes: 1) a carbon-fiber microelectrode (CFM) to measure dopamine; 2) a glutamate oxidase enzyme-linked electrode to measure glutamate; and 3) a multiple enzyme-linked electrode (adenosine deaminase, nucleoside phosphorylase, and xanthine oxidase) to measure adenosine. Proof-of-principle analyses included noise assessments and in vitro and in vivo measurements that were compared with similar analyses by using a commercial hardwired electrochemical system (EA161 Picostat, eDAQ; Pty Ltd). In urethane-anesthetized rats, dopamine release was monitored in the striatum following deep brain stimulation (DBS) of ascending dopaminergic fibers in the medial forebrain bundle (MFB). In separate rat experiments, DBS-evoked adenosine release was monitored in the ventrolateral thalamus. To test the WINCS in an operating room setting resembling human neurosurgery, cortical glutamate release in response to motor cortex stimulation (MCS) was monitored using a large-mammal animal model, the pig. The WINCS, which is designed in compliance with FDA-recognized consensus standards for medical electrical device safety, successfully measured dopamine, glutamate, and adenosine, both in vitro and in vivo. The WINCS detected striatal dopamine release at the implanted CFM during DBS of the MFB. The DBS-evoked adenosine release in the rat thalamus and MCS-evoked glutamate release in the pig cortex were also successfully measured. Overall, in vitro and in vivo testing demonstrated signals comparable to a commercial hardwired electrochemical system for FPA. By incorporating FPA, the chemical repertoire of WINCS-measurable neurotransmitters is expanded to include glutamate and other nonelectroactive species for which the evolving field of enzyme-linked biosensors exists. Because many neurotransmitters are not electrochemically active, FPA in combination with enzyme-linked microelectrodes represents a powerful intraoperative tool for rapid and selective neurochemical sampling in important anatomical targets during functional neurosurgery.
NASA Astrophysics Data System (ADS)
Liu, Hai-Zheng; Shi, Ze-Lin; Feng, Bin; Hui, Bin; Zhao, Yao-Hong
2016-03-01
Integrating microgrid polarimeters on focal plane array (FPA) of an infrared detector causes non-uniformity of polarization response. In order to reduce the effect of polarization non-uniformity, this paper constructs an experimental setup for capturing raw flat-field images and proposes a procedure for acquiring non-uniform calibration (NUC) matrix and calibrating raw polarization images. The proposed procedure takes the incident radiation as a polarization vector and offers a calibration matrix for each pixel. Both our matrix calibration and two-point calibration are applied to our mid-wavelength infrared (MWIR) polarization imaging system with integrated microgrid polarimeters. Compared with two point calibration, our matrix calibration reduces non-uniformity by 30 40% under condition of flat-field data test with polarization. The ourdoor scene observation experiment indicates that our calibration can effectively reduce polarization non-uniformity and improve the image quality of our MWIR polarization imaging system.
Validating Phasing and Geometry of Large Focal Plane Arrays
NASA Technical Reports Server (NTRS)
Standley, Shaun P.; Gautier, Thomas N.; Caldwell, Douglas A.; Rabbette, Maura
2011-01-01
The Kepler Mission is designed to survey our region of the Milky Way galaxy to discover hundreds of Earth-sized and smaller planets in or near the habitable zone. The Kepler photometer is an array of 42 CCDs (charge-coupled devices) in the focal plane of a 95-cm Schmidt camera onboard the Kepler spacecraft. Each 50x25-mm CCD has 2,200 x 1,024 pixels. The CCDs accumulate photons and are read out every six seconds to prevent saturation. The data is integrated for 30 minutes, and then the pixel data is transferred to onboard storage. The data is subsequently encoded and transmitted to the ground. During End-to-End Information System (EEIS) testing of the Kepler Mission System (KMS), there was a need to verify that the pixels requested by the science team operationally were correctly collected, encoded, compressed, stored, and transmitted by the FS, and subsequently received, decoded, uncompressed, and displayed by the Ground Segment (GS) without the outputs of any CCD modules being flipped, mirrored, or otherwise corrupted during the extensive FS and GS processing. This would normally be done by projecting an image on the focal plane array (FPA), collecting the data in a flight-like way, and making a comparison between the original data and the data reconstructed by the science data system. Projecting a focused image onto the FPA through the telescope would normally involve using a collimator suspended over the telescope opening. There were several problems with this approach: the collimation equipment is elaborate and expensive; as conceived, it could only illuminate a limited section of the FPA (.25 percent) during a given test; the telescope cover would have to be deployed during testing to allow the image to be projected into the telescope; the equipment was bulky and difficult to situate in temperature-controlled environments; and given all the above, test setup, execution, and repeatability were significant concerns. Instead of using this complicated approach of projecting an optical image on the FPA, the Kepler project developed a method using known defect features in the CCDs to verify proper collection and reassembly of the pixels, thereby avoiding the costs and risks of the optical projection approach. The CCDs composing the Kepler FPA, as all CCDs, had minor defects. At ambient temperature, some pixels look far brighter than they should. These ghot h pixels have a higher rate of charge leakage than the others due to manufacturing variations. They are usually stable over time, and appear at temperatures above 5 oC. The hot pixels on the Kepler FPA were mapped before photometer assembly during module testing. Selected hot pixels were used as target gstars h for the purposes of EEIS testing. gDead h pixels are permanently off, producing a permanently black pixel. These can also be used if there is some illumination of the FPA. During EEIS testing, Dark Current Full Frame Images (FFIs) taken at room temperature were used to create the hot pixel maps for all 84 Kepler photometer CCD channels. Data from two separate nights were used to create two hot pixel maps per channel, which were cross-correlated to remove cosmic ray events which appear to be hot pixels. These hot pixel maps obtained during EEIS testing were compared to the maps made during module testing to verify that the end-to-end data flow was correct.
Providing choices for a marginalized community. A community-based project with Malaysian aborigines.
Kaur, P
1994-01-01
In 1991, the Family Planning Association (FPA) of the Malaysian state of Perak initiated a community-based development project in the remote Aborigine village of Kampung Tisong. The community consists of approximately 34 households who survive on an average income of about US $37. Malnutrition is pervasive, even minor ailments cause death, more serious afflictions are prevalent, and the closest government clinic is 20 kilometers away and seldom used by the Aborigines. 70% of the children have access to education, but parental illiteracy is a serious educational obstacle. The goals of the FPA program are to 1) promote maternal and child health and responsible parenthood, 2) provide health education, 3) encourage women to seek self-determination, and 4) encourage the development of self-reliance in the community as a whole. The first step was to survey the community's culture, beliefs, and health status with the help of the Aborigines Department and the village headman. After a series of preliminary meetings with other agencies, the FPA began to provide activities including health talks, health courses and demonstrations, medical examinations and check-ups, and first aid training. Environmental protection and sanitation measures were included in the educational activities, and following the traditional "mutual aid system," a small plot of land was cleared for vegetable production. Vegetable gardens and needlecraft will become income-producing activities for the women. Attempts to motivate the women to use family planning have been hindered by the fact that the health of 2 women deteriorated after they began using oral contraceptives. Positive changes are occurring slowly and steadily, however, and the FPA has been instrumental in having the settlement included in a program for the hardcore poor which will provide new housing and farming projects.
COUGAR: a liquid nitrogen cooled InGaAs camera for astronomy and electro-luminescence
NASA Astrophysics Data System (ADS)
Van Bogget, Urbain; Vervenne, Vincent; Vinella, Rosa Maria; van der Zanden, Koen; Merken, Patrick; Vermeiren, Jan
2014-06-01
A SWIR FPA was designed and manufactured with 640*512 pixels, 20 μm pitch and InGaAs detectors for electroluminescence characterization and astronomical applications in the [0.9 - 1.55 μm] range. The FPA is mounted in a liquid nitrogen dewar and is operated by a low noise frontend electronics. One of the biggest problem in designing sensors and cameras for electro-luminescence measurements is the autoillumination of the detectors by the readout circuit. Besides of proper shielding of the detectors, the ROIC shall be optimized for minimal electrical activity during the integration time of the very-weak signals coming from the circuit under test. For this reason a SFD (or Source Follower per Detector) architecture (like in the Hawaii sensor) was selected, resulting in a background limited performance of the detector. The pixel has a (somewhat arbitrary) full well capacity of 400 000 e- and a sensitivity of 2.17 μV/e-. The dark signal is app. 1 e-/pixel/sec and with the appropriate Fowler sampling the dark noise lowers below 5 e-rms. The power consumption of the circuit is limited 2 mW, allowing more than 24 hours of operation on less than 1 l of liquid nitrogen. The FPA is equipped with 4 outputs (optional readout on one single channel) and is capable of achieving 3 frames per second. Due to the non-destructive readout it is possible to determine in a dynamic way the optimal integration time for each observation. The Cougar camera is equipped with ultra-low noise power supply and bias lines; the electronics contain also a 24 bit AD converter to fully exploit the sensitivity of the FPA and the camera.
Multi sensor satellite imagers for commercial remote sensing
NASA Astrophysics Data System (ADS)
Cronje, T.; Burger, H.; Du Plessis, J.; Du Toit, J. F.; Marais, L.; Strumpfer, F.
2005-10-01
This paper will discuss and compare recent refractive and catodioptric imager designs developed and manufactured at SunSpace for Multi Sensor Satellite Imagers with Panchromatic, Multi-spectral, Area and Hyperspectral sensors on a single Focal Plane Array (FPA). These satellite optical systems were designed with applications to monitor food supplies, crop yield and disaster monitoring in mind. The aim of these imagers is to achieve medium to high resolution (2.5m to 15m) spatial sampling, wide swaths (up to 45km) and noise equivalent reflectance (NER) values of less than 0.5%. State-of-the-art FPA designs are discussed and address the choice of detectors to achieve these performances. Special attention is given to thermal robustness and compactness, the use of folding prisms to place multiple detectors in a large FPA and a specially developed process to customize the spectral selection with the need to minimize mass, power and cost. A refractive imager with up to 6 spectral bands (6.25m GSD) and a catodioptric imager with panchromatic (2.7m GSD), multi-spectral (6 bands, 4.6m GSD), hyperspectral (400nm to 2.35μm, 200 bands, 15m GSD) sensors on the same FPA will be discussed. Both of these imagers are also equipped with real time video view finding capabilities. The electronic units could be subdivided into the Front-End Electronics and Control Electronics with analogue and digital signal processing. A dedicated Analogue Front-End is used for Correlated Double Sampling (CDS), black level correction, variable gain and up to 12-bit digitizing and high speed LVDS data link to a mass memory unit.
Bayerle-Eder, M; Kolodjaschna, J; Wolzt, M; Polska, E; Gasic, S; Schmetterer, L
2005-01-01
Background: The ocular pressure/volume relation, which is described by the Friedenwald equation, forms the basis of intraocular pressure (IOP) measurement with Schiotz tonometry and measurement of pulsatile ocular blood flow (POBF) with pneumotonometry. Changes in intraocular volume during the cardiac cycle are caused by arterial inflow and venous outflow and are accompanied by changes in IOP. The relation between volume and pressure changes is dependent on the elastic properties of the eye coats as described by the ocular rigidity coefficient. Previous studies indicate that there is a vascular contribution to ocular rigidity and that the volume/pressure relationship may depend on the mean arterial pressure. Methods: The effect of a nifedipine induced reduction in systemic blood pressure on pulse amplitude (PA) as assessed with pneumotonometry and fundus pulsation amplitude (FPA), as measured with laser interferometry was investigated in 16 untreated patients with moderate to severe systemic hypertension (mean arterial pressure 123 (SD 12) mm Hg). Results: The ratio between PA and FPA was taken as a measure of the ocular rigidity coefficient. Nifedipine reduced mean arterial pressure by 17.3% and increased pulse rate by 11.0% (p<0.001 each). Whereas PA was significantly reduced after administration of nifedipine (−15.6%; p<0.001), FPA remained unchanged. Accordingly, the ratio of PA/FPA was reduced from 0.86 mm Hg/μm to 0.73 mm Hg/μm after administration of nifedipine. Conclusion: These data are in keeping with previous animal experiments indicating a blood pressure dependent vascular component to the rigidity of the eye coats in vivo. This needs to be taken into account for measurement of IOP with Schiotz tonometry and POBF with pneumotonometry. PMID:15923506
Mitigation of image artifacts in LWIR microgrid polarimeter images
NASA Astrophysics Data System (ADS)
Ratliff, Bradley M.; Tyo, J. Scott; Boger, James K.; Black, Wiley T.; Bowers, David M.; Kumar, Rakesh
2007-09-01
Microgrid polarimeters, also known as division of focal plane (DoFP) polarimeters, are composed of an integrated array of micropolarizing elements that immediately precedes the FPA. The result of the DoFP device is that neighboring pixels sense different polarization states. The measurements made at each pixel can be combined to estimate the Stokes vector at every reconstruction point in a scene. DoFP devices have the advantage that they are mechanically rugged and inherently optically aligned. However, they suffer from the severe disadvantage that the neighboring pixels that make up the Stokes vector estimates have different instantaneous fields of view (IFOV). This IFOV error leads to spatial differencing that causes false polarization signatures, especially in regions of the image where the scene changes rapidly in space. Furthermore, when the polarimeter is operating in the LWIR, the FPA has inherent response problems such as nonuniformity and dead pixels that make the false polarization problem that much worse. In this paper, we present methods that use spatial information from the scene to mitigate two of the biggest problems that confront DoFP devices. The first is a polarimetric dead pixel replacement (DPR) scheme, and the second is a reconstruction method that chooses the most appropriate polarimetric interpolation scheme for each particular pixel in the image based on the scene properties. We have found that these two methods can greatly improve both the visual appearance of polarization products as well as the accuracy of the polarization estimates, and can be implemented with minimal computational cost.
Quantum efficiency investigations of type-II InAs/GaSb midwave infrared superlattice photodetectors
DOE Office of Scientific and Technical Information (OSTI.GOV)
Giard, E., E-mail: edouard.giard@onera.fr; Ribet-Mohamed, I.; Jaeck, J.
2014-07-28
We present in this paper a comparison between different type-II InAs/GaSb superlattice (T2SL) photodiodes and focal plane array (FPA) in the mid-wavelength infrared domain to understand which phenomenon drives the performances of the T2SL structure in terms of quantum efficiency (QE). Our measurements on test photodiodes suggest low minority carrier diffusion length in the “InAs-rich” design, which penalizes carriers' collection in this structure for low bias voltage and front side illumination. This analysis is completed by a comparison of the experimental data with a fully analytic model, which allows to infer a hole diffusion length shorter than 100 nm. In addition,more » measurements on a FPA with backside illumination are finally presented. Results show an average QE in the 3–4.7 μm window equal to 42% for U{sub bias} = −0.1 V, 77 K operating temperature and no anti-reflection coating. These measurements, completed by modulation transfer function and noise measurements, reveal that the InAs-rich design, despite a low hole diffusion length, is promising for high performance infrared imaging applications.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Vishnyakov, A. V.; Stuchinsky, V. A., E-mail: stuchin@isp.nsc.ru; Brunev, D. V.
2014-03-03
In the present paper, we propose a method for evaluating the bulk diffusion length of minority charge carriers in the photosensing layer of photovoltaic focal plane array (FPA) photodetectors. The method is based on scanning a strip-shaped illumination spot with one of the detector diodes at a low level of photocurrents j{sub ph} being registered; such scanning provides data for subsequent analysis of measured spot-scan profiles within a simple diffusion model. The asymptotic behavior of the effective (at j{sub ph} ≠ 0) charge-carrier diffusion length l{sub d} {sub eff} as a function of j{sub ph} for j{sub ph} → 0 inferred frommore » our experimental data proved to be consistent with the behavior of l{sub d} {sub eff} vs j{sub ph} as predicted by the model, while the obtained values of the bulk diffusion length of minority carriers (electrons) in the p-HgCdTe film of investigated HgCdTe n-on-p FPA photodetectors were found to be in a good agreement with the previously reported carrier diffusion-length values for HgCdTe.« less
NASA Astrophysics Data System (ADS)
Haka, Abigail S.; Kidder, Linda H.; Lewis, E. Neil
2001-07-01
We have applied Fourier transform infrared (FTIR) spectroscopic imaging, coupling a mercury cadmium telluride (MCT) focal plane array detector (FPA) and a Michelson step scan interferometer, to the investigation of various states of malignant human prostate tissue. The MCT FPA used consists of 64x64 pixels, each 61 micrometers 2, and has a spectral range of 2-10.5 microns. Each imaging data set was collected at 16-1 resolution, resulting in 512 image planes and a total of 4096 interferograms. In this article we describe a method for separating different tissue types contained within FTIR spectroscopic imaging data sets of human prostate tissue biopsies. We present images, generated by the Fuzzy C-Means clustering algorithm, which demonstrate the successful partitioning of distinct tissue type domains. Additionally, analysis of differences in the centroid spectra corresponding to different tissue types provides an insight into their biochemical composition. Lastly, we demonstrate the ability to partition tissue type regions in a different data set using centroid spectra calculated from the original data set. This has implications for the use of the Fuzzy C-Means algorithm as an automated technique for the separation and examination of tissue domains in biopsy samples.
Inter-Rater Reliability of Cyclotorsion Measurements Using Fundus Photography.
Dysli, Muriel; Kanku, Madeleine; Traber, Ghislaine L
2018-04-01
The foveo-papillary angle (FPA) on fundus photographs is the accepted standard for the measurement of ocular cyclotorsion. We assessed the inter-rater reliability of this method in healthy subjects and in patients with trochlear nerve palsies. In this methodological study, fundus photographs of healthy subjects and of patients with trochlear nerve palsies were made with a fundus camera (Zeiss Fundus Camera FF 450 plus, Jena, Germany). Three independent observers measured the FPA on the fundus photographs of all subjects in synedra View (synedra View 16, Version 16.0.0.11, Innsbruck, Austria). One hundred and four eyes of 52 subjects (26 healthy controls and 26 patients) were assessed. The mean FPA of the healthy controls was 5.80 degrees (°) [± 0.44 standard error of the mean (SEM)] compared to 11.55° (± 0.80 SEM) for patients with trochlear nerve palsies. The inter-rater reliability of all measured FPAs showed an intraclass correlation coefficient (ICC) of 0.98 (95% CI 0.97 - 0.98). The inter-rater reliability of objective cyclotorsion measurements using fundus photographs was very high. Georg Thieme Verlag KG Stuttgart · New York.
A miniature low-cost LWIR camera with a 160×120 microbolometer FPA
NASA Astrophysics Data System (ADS)
Tepegoz, Murat; Kucukkomurler, Alper; Tankut, Firat; Eminoglu, Selim; Akin, Tayfun
2014-06-01
This paper presents the development of a miniature LWIR thermal camera, MSE070D, which targets value performance infrared imaging applications, where a 160x120 CMOS-based microbolometer FPA is utilized. MSE070D features a universal USB interface that can communicate with computers and some particular mobile devices in the market. In addition, it offers high flexibility and mobility with the help of its USB powered nature, eliminating the need for any external power source, thanks to its low-power requirement option. MSE070D provides thermal imaging with its 1.65 inch3 volume with the use of a vacuum packaged CMOS-based microbolometer type thermal sensor MS1670A-VP, achieving moderate performance with a very low production cost. MSE070D allows 30 fps thermal video imaging with the 160x120 FPA size while resulting in an NETD lower than 350 mK with f/1 optics. It is possible to obtain test electronics and software, miniature camera cores, complete Application Programming Interfaces (APIs) and relevant documentation with MSE070D, as MikroSens want to help its customers to evaluate its products and to ensure quick time-to-market for systems manufacturers.
Compact Focal Plane Assembly for Planetary Science
NASA Technical Reports Server (NTRS)
Brown, Ari; Aslam, Shahid; Huang, Wei-Chung; Steptoe-Jackson, Rosalind
2013-01-01
A compact radiometric focal plane assembly (FPA) has been designed in which the filters are individually co-registered over compact thermopile pixels. This allows for construction of an ultralightweight and compact radiometric instrument. The FPA also incorporates micromachined baffles in order to mitigate crosstalk and low-pass filter windows in order to eliminate high-frequency radiation. Compact metal mesh bandpass filters were fabricated for the far infrared (FIR) spectral range (17 to 100 microns), a game-changing technology for future planetary FIR instruments. This fabrication approach allows the dimensions of individual metal mesh filters to be tailored with better than 10- micron precision. In contrast, conventional compact filters employed in recent missions and in near-term instruments consist of large filter sheets manually cut into much smaller pieces, which is a much less precise and much more labor-intensive, expensive, and difficult process. Filter performance was validated by integrating them with thermopile arrays. Demonstration of the FPA will require the integration of two technologies. The first technology is compact, lightweight, robust against cryogenic thermal cycling, and radiation-hard micromachined bandpass filters. They consist of a copper mesh supported on a deep reactive ion-etched silicon frame. This design architecture is advantageous when constructing a lightweight and compact instrument because (1) the frame acts like a jig and facilitates filter integration with the FPA, (2) the frame can be designed so as to maximize the FPA field of view, (3) the frame can be simultaneously used as a baffle for mitigating crosstalk, and (4) micron-scale alignment features can be patterned so as to permit high-precision filter stacking and, consequently, increase the filter bandwidth and sharpen the out-of-band rolloff. The second technology consists of leveraging, from another project, compact and lightweight Bi0.87Sb0.13/Sb arrayed thermopiles. These detectors consist of 30-layer thermopiles deposited in series upon a silicon nitride membrane. At 300 K, the thermopile arrays are highly linear over many orders of magnitude of incident IR power, and have a reported specific detectivity that exceeds the requirements imposed on future mission concepts. The bandpass filter array board is integrated with a thermopile array board by mounting both boards on a machined aluminum jig.
Can We Measure the Heel Bump? Radiographic Evaluation of Haglund's Deformity.
Bulstra, Gythe H; van Rheenen, Thijs A; Scholtes, Vanessa A B
2015-01-01
Haglund's deformity is a symptomatic posterosuperior deformity of the heel. The lateral radiograph of the ankle will show a prominent, large, posterosuperior part of the calcaneus, which can be measured using the Fowler and Philips angle (FPA, the angle between the posterior and plantar surface of the calcaneus) and the calcaneal pitch angle (CPA, the angle between the sole of the foot and the plantar part of the calcaneus). Although these angles are commonly used, these radiographic angle measurements have never shown a relationship with Haglund's deformity. In 78 patients (51% male) with symptomatic Haglund's deformity and a control group of 100 patients (41% male) with no heel complaints, we measured the FPA and CPA on weightbearing lateral radiographs of the foot. Using an unpaired t tests, no significant difference was found between the 2 groups in the FPA (p = .40). We measured a significant difference in the CPA between the Haglund group and the control group (p = .014). Subgroup analysis showed that this difference was mainly found in females (p < .00), with no significant difference seen in the males (p < .48). Females with Haglund's deformity will have a greater CPA than will females without Haglund's deformity. The CPA showed a difference between the Haglund and non-Haglund groups, although mainly in females. Although the evidence from our study is limited, it would be interesting to study the CPA further, because it implicates the verticalization of the calcaneus. This change in position results in extra traction on the Achilles tendon and can eventually cause tendinitis and bursitis. Radiographic measurement should be used as an auxiliary tool. If the calcaneus tends to change position, it would be interesting to understand this process, which could eventually lead to improvement in the treatment of Haglund's deformity. Copyright © 2015 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.
Focal plane arrays based on Type-II indium arsenide/gallium antimonide superlattices
NASA Astrophysics Data System (ADS)
Delaunay, Pierre-Yves
The goal of this work is to demonstrate that Type-II InAs/GaSb superlattices can perform high quality infrared imaging from the middle (MWIR) to the long (LWIR) wavelength infrared range. Theoretically, focal plane arrays (FPAs) based on this technology could be operated at higher temperatures, with lower dark currents than the leading HgCdTe platform. This effort will focus on the fabrication of MWIR and LWIR FPAs with performance similar to existing infrared cameras. Some applications in the MWIR require fast, sensitive imagers able to sustain frame rates up to 100Hz. Such speed can only be achieved with photon detectors. However, these cameras need to be operated below 170K. Current research in this spectral band focuses on increasing the operating temperature of the FPA to a point where cooling could be performed with compact and reliable thermoelectric coolers. Type-II superlattice was used to demonstrate a camera that presented similar performance to HgCdTe and that could be operated up to room temperature. At 80K, the camera could detect temperature differences as low as 10 mK for an integration time shorter than 25 ms. In the LWIR, the electric performance of Type-II photodiodes is mainly limited by surface leakage. Aggressive processing steps such as hybridization and underfill can increase the dark current of the devices by several orders of magnitude. New cleaning and passivation techniques were used to reduce the dark current of FPA diodes by two orders of magnitudes. The absorbing GaSb substrate was also removed to increase the quantum efficiency of the devices up to 90%. At 80K, a FPA with a 9.6 microm 50%-cutoff in responsivity was able to detect temperature differences as low as 19 mK, only limited by the performance of the testing system. The non-uniformity in responsivity reached 3.8% for a 98.2% operability. The third generation of infrared cameras is based on multi-band imaging in order to improve the recognition capabilities of the imager. Preliminary detectors based on back to back diodes presented similar performance to single colors devices; the quantum efficiency was measured higher than 40% for both bands. Preliminary imaging results were demonstrated in the LWIR.
Four faces of the interaction between ions and aromatic rings.
Papp, Dóra; Rovó, Petra; Jákli, Imre; Császár, Attila G; Perczel, András
2017-07-15
Non-covalent interactions between ions and aromatic rings play an important role in the stabilization of macromolecular complexes; of particular interest are peptides and proteins containing aromatic side chains (Phe, Trp, and Tyr) interacting with negatively (Asp and Glu) and positively (Arg and Lys) charged amino acid residues. The structures of the ion-aromatic-ring complexes are the result of an interaction between the large quadrupole moment of the ring and the charge of the ion. Four attractive interaction types are proposed to be distinguished based on the position of the ion with respect to the plane of the ring: perpendicular cation-π (CP ⊥ ), co-planar cation-π (CP ∥ ), perpendicular anion-π (AP ⊥ ), and co-planar anion-π (AP ∥ ). To understand more than the basic features of these four interaction types, a systematic, high-level quantum chemical study is performed, using the X - + C 6 H 6 , M + + C 6 H 6 , X - + C 6 F 6 , and M + + C 6 F 6 model systems with X - = H - , F - , Cl - , HCOO - , CH 3 COO - and M + = H + , Li + , Na + , NH4+, CH 3 NH3+, whereby C 6 H 6 and C 6 F 6 represent an electron-rich and an electron-deficient π system, respectively. Benchmark-quality interaction energies with small uncertainties, obtained via the so-called focal-point analysis (FPA) technique, are reported for the four interaction types. The computations reveal that the interactions lead to significant stabilization, and that the interaction energy order, given in kcal mol -1 in parentheses, is CP ⊥ (23-37) > AP ⊥ (14-21) > CP ∥ (9-22) > AP ∥ (6-16). A natural bond orbital analysis performed leads to a deeper qualitative understanding of the four interaction types. To facilitate the future quantum chemical characterization of ion-aromatic-ring interactions in large biomolecules, the performance of three density functional theory methods, B3LYP, BHandHLYP, and M06-2X, is tested against the FPA benchmarks, with the result that the M06-2X functional performs best. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.
Large size MOEMS Fabry-Perot interferometer filter for focal plane array hyperspectral imaging
NASA Astrophysics Data System (ADS)
Chee, J.; Hwu, J.; Kim, T. S.; Kubby, J.; Velicu, S.; Gupta, N.
2015-02-01
Focal plane array (FPA) technology is mature and is widely used for imaging applications. However, FPAs have broadband responses which limit their ability to provide high performance in hyperspectral applications such as detection of buried explosives, and identifying the presence of explosive chemicals and their concentrations. EPIR is currently developing Micro-Opto-Electro-Mechanical System (MOEMS) Fabry-Perot interferometer filter (FPF) devices for FPAs. In this paper, we present our approach to MOEMS FPF design and fabrication that will meet the size requirements for large format FPA hyperspectral imaging. We also report the performance of our FPF resonance cavity, capable of up to 3 μm change gap in tens of nanometer increments.
Methodology for testing infrared focal plane arrays in simulated nuclear radiation environments
NASA Astrophysics Data System (ADS)
Divita, E. L.; Mills, R. E.; Koch, T. L.; Gordon, M. J.; Wilcox, R. A.; Williams, R. E.
1992-07-01
This paper summarizes test methodology for focal plane array (FPA) testing that can be used for benign (clear) and radiation environments, and describes the use of custom dewars and integrated test equipment in an example environment. The test methodology, consistent with American Society for Testing Materials (ASTM) standards, is presented for the total accumulated gamma dose, transient dose rate, gamma flux, and neutron fluence environments. The merits and limitations of using Cobalt 60 for gamma environment simulations and of using various fast-neutron reactors and neutron sources for neutron simulations are presented. Test result examples are presented to demonstrate test data acquisition and FPA parameter performance under different measurement conditions and environmental simulations.
Tagg, Alexander S; Sapp, Melanie; Harrison, Jesse P; Ojeda, Jesús J
2015-06-16
Microplastics (<5 mm) have been documented in environmental samples on a global scale. While these pollutants may enter aquatic environments via wastewater treatment facilities, the abundance of microplastics in these matrices has not been investigated. Although efficient methods for the analysis of microplastics in sediment samples and marine organisms have been published, no methods have been developed for detecting these pollutants within organic-rich wastewater samples. In addition, there is no standardized method for analyzing microplastics isolated from environmental samples. In many cases, part of the identification protocol relies on visual selection before analysis, which is open to bias. In order to address this, a new method for the analysis of microplastics in wastewater was developed. A pretreatment step using 30% hydrogen peroxide (H2O2) was employed to remove biogenic material, and focal plane array (FPA)-based reflectance micro-Fourier-transform (FT-IR) imaging was shown to successfully image and identify different microplastic types (polyethylene, polypropylene, nylon-6, polyvinyl chloride, polystyrene). Microplastic-spiked wastewater samples were used to validate the methodology, resulting in a robust protocol which was nonselective and reproducible (the overall success identification rate was 98.33%). The use of FPA-based micro-FT-IR spectroscopy also provides a considerable reduction in analysis time compared with previous methods, since samples that could take several days to be mapped using a single-element detector can now be imaged in less than 9 h (circular filter with a diameter of 47 mm). This method for identifying and quantifying microplastics in wastewater is likely to provide an essential tool for further research into the pathways by which microplastics enter the environment.
Tang, Hongbo; Chen, Hongli; Jia, Yajing; Liu, Xiaoyan; Han, Zhaohong; Wang, Aihua; Liu, Qi; Li, Xinlei; Feng, Xin
2017-01-01
The regular accumulation of nanoparticles in the liver makes them hepatotoxic and decreases the circulation time, thus reducing their therapeutic effect. Resolving this problem will be significant in improving bioavailability and reducing side effects. In this study, we reduced the phagocytosis of epirubicin (EPI)-loaded folic acid-conjugated pullulan acetate (FPA/EPI) nanoparticles by Kupffer cells (KCs) through internalization and nuclear factor kappa B (NF-kB) signal pathway inhibitors, thus allowing development of FPA/EPI nanoparticles as a nanodrug delivery system (NDDS) based on our previous study. FPA/EPI nanoparticles were prepared by the dialysis method. Rat KCs were preincubated with the following individual or compound inhibitors: chlorpromazine (CPZ), nystatin (NY), colchicine (Col), amiloride (AMR), and pyrrolidine dithiocarbamate (PDTC). Dose- and time-dependent cellular uptake effects of inhibitors on FPA/EPI nanoparticles were determined through fluorometry. The cytokine levels of tumor necrosis factor alpha (TNF-α), interleukin-1 beta (IL-1β), and IL-6 were tested in culture supernatants by bead-based multiplex flow cytometry. The uptake study demonstrated that inhibitors had an obvious inhibitory effect ( P <0.05 or P <0.01), with NY, AMR and Col all showing time-dependent inhibitory effects. PDTC + NY had the strongest inhibitory effect, with an uptake rate of 14.62%. The levels of the three proinflammatory cytokines were changed significantly by the compound inhibitors. TNF-α was significantly inhibited ( P <0.05 or P <0.01), but IL-1β and IL-6 showed smaller decreases. These results suggested that clathrin- and caveolae-mediated endocytosis were the main routes via which nanoparticles entered KCs and that the NF-kB signal pathway was very important too. In summary, multiple mechanisms, including clathrin- and caveolae-mediated endocytosis, contribute to cytokine production in macrophages following exposure to folic acid-conjugated pullulan acetate nanoparticles. Thus, the endocytosis inhibition strategy has great potential for improving therapy and reducing toxicity of an NDDS in the treatment of cancer.
NASA Astrophysics Data System (ADS)
Gambicorti, L.; Piazza, D.; Gerber, M.; Pommerol, A.; Roloff, V.; Ziethe, R.; Zimmermann, C.; Da Deppo, V.; Cremonese, G.; Ficai Veltroni, I.; Marinai, M.; Di Carmine, E.; Bauer, T.; Moebius, P.; Thomas, N.
2016-08-01
A new technique based on photolithographic processes of thin-film optical pass band coatings on a monolithic substrate has been applied to the filters of the Focal Plane Assembly (FPA) of the Colour and Stereo Surface Imaging System (CaSSIS) that will fly onboard of the ExoMars Trace Gas Orbiter to be launched in March 2016 by ESA. The FPA including is one of the spare components of the Simbio-Sys instrument of the Italian Space Agency (ASI) that will fly on ESA's Bepi Colombo mission to Mercury. The detector, developed by Raytheon Vision Systems, is a 2kx2k hybrid Si-PIN array with a 10 μm pixel. The detector is housed within a block and has filters deposited directly on the entrance window. The window is a 1 mm thick monolithic plate of fused silica. The Filter Strip Assembly (FSA) is produced by Optics Balzers Jena GmbH and integrated on the focal plane by Leonardo-Finmeccanica SpA (under TAS-I responsibility). It is based on dielectric multilayer interference coatings, 4 colour bands selected with average in-band transmission greater than 95 percent within wavelength range (400-1100 nm), giving multispectral images on the same detector and thus allows CaSSIS to operate in push-frame mode. The Field of View (FOV) of each colour band on the detector is surrounded by a mask of low reflective chromium (LRC), which also provides with the straylight suppression required (an out-of-band transmission of less than 10-5/nm). The mask has been shown to deal effectively with cross-talk from multiple reflections between the detector surface and the filter. This paper shows the manufacturing and optical properties of the FSA filters and the FPA preliminary on-ground calibration results.
A grid-connected single-phase photovoltaic micro inverter
NASA Astrophysics Data System (ADS)
Wen, X. Y.; Lin, P. J.; Chen, Z. C.; Wu, L. J.; Cheng, S. Y.
2017-11-01
In this paper, the topology of a single-phase grid-connected photovoltaic (PV) micro-inverter is proposed. The PV micro-inverter consists of DC-DC stage with high voltage gain boost and DC-AC conversion stage. In the first stage, we apply the active clamp circuit and two voltage multipliers to achieve soft switching technology and high voltage gain. In addition, the flower pollination algorithm (FPA) is employed for the maximum power point tracking (MPPT) in the PV module in this stage. The second stage cascades a H-bridge inverter and LCL filter. To feed high quality sinusoidal power into the grid, the software phase lock, outer voltage loop and inner current loop control method are adopted as the control strategy. The performance of the proposed topology is tested by Matlab/Simulink. A PV module with maximum power 300W and maximum power point voltage 40V is applied as the input source. The simulation results indicate that the proposed topology and the control strategy are feasible.
Lupoi, Jason S.; Smith-Moritz, Andreia; Singh, Seema; ...
2015-07-10
Background: Slow-degrading, fossil fuel-derived plastics can have deleterious effects on the environment, especially marine ecosystems. The production of bio-based, biodegradable plastics from or in plants can assist in supplanting those manufactured using fossil fuels. Polyhydroxybutyrate (PHB) is one such biodegradable polyester that has been evaluated as a possible candidate for relinquishing the use of environmentally harmful plastics. Results: PHB, possessing similar properties to polyesters produced from non-renewable sources, has been previously engineered in sugarcane, thereby creating a high-value co-product in addition to the high biomass yield. This manuscript illustrates the coupling of a Fourier-transform infrared microspectrometer, equipped with a focalmore » plane array (FPA) detector, with multivariate imaging to successfully identify and localize PHB aggregates. Principal component analysis imaging facilitated the mining of the abundant quantity of spectral data acquired using the FPA for distinct PHB vibrational modes. PHB was measured in the chloroplasts of mesophyll and bundle sheath cells, acquiescent with previously evaluated plant samples. Conclusion: This study demonstrates the power of IR microspectroscopy to rapidly image plant sections to provide a snapshot of the chemical composition of the cell. While PHB was localized in sugarcane, this method is readily transferable to other value-added co-products in different plants.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lupoi, Jason S.; Smith-Moritz, Andreia; Singh, Seema
Background: Slow-degrading, fossil fuel-derived plastics can have deleterious effects on the environment, especially marine ecosystems. The production of bio-based, biodegradable plastics from or in plants can assist in supplanting those manufactured using fossil fuels. Polyhydroxybutyrate (PHB) is one such biodegradable polyester that has been evaluated as a possible candidate for relinquishing the use of environmentally harmful plastics. Results: PHB, possessing similar properties to polyesters produced from non-renewable sources, has been previously engineered in sugarcane, thereby creating a high-value co-product in addition to the high biomass yield. This manuscript illustrates the coupling of a Fourier-transform infrared microspectrometer, equipped with a focalmore » plane array (FPA) detector, with multivariate imaging to successfully identify and localize PHB aggregates. Principal component analysis imaging facilitated the mining of the abundant quantity of spectral data acquired using the FPA for distinct PHB vibrational modes. PHB was measured in the chloroplasts of mesophyll and bundle sheath cells, acquiescent with previously evaluated plant samples. Conclusion: This study demonstrates the power of IR microspectroscopy to rapidly image plant sections to provide a snapshot of the chemical composition of the cell. While PHB was localized in sugarcane, this method is readily transferable to other value-added co-products in different plants.« less
The texture, sensory properties and stability of cookies prepared with wax oleogels.
Yılmaz, Emin; Öğütcü, Mustafa
2015-04-01
Shortening is the essential component of high quality baked foods. Its effects on dough structure formation and the desired final product attributes depend mostly on its solid fat content and β' crystalline polymorphs. Saturated and trans fatty acids present in shortening pose some important negative health considerations. Hence, alternative plastic fats with lower or zero quantity of saturated and trans fatty acids are in high demand. Oleogels are gel networks of liquid edible oils with no trans and very low saturated fatty acids. In this study, sunflower wax (SW) and beeswax (BW) oleogels of hazelnut oil were used in cookie preparation against commercial bakery shortening (CBS) as the control, to compare the textural, sensory and stability properties of the cookies. The basic chemical composition, textural properties, and some physical attributes of the cookies were compared. Sensory texture/flavor profile analysis (T/FPA) and consumer hedonic tests were also accomplished. Furthermore, the changes in cookie texture and stability were monitored during 30 day storage at room temperature. It was found out that in almost all properties, the oleogel cookies resembled CBS cookies. T/FPA results present detailed data for literature. Consumer hedonic scores indicated that oleogel cookies were better than CBS cookies and were also well accepted by consumers. Wax oleogels can be used as cookie shortening successfully.
LWIR hyperspectral imager based on a diffractive optics lens
NASA Astrophysics Data System (ADS)
Gupta, Neelam
2009-05-01
A diffractive optics lens based longwave infrared hyperspectral imager has been used to collect laboratory and outdoor field test data. The imager uses a specially designed diffractive optics Ge lens with a 320×256 HgCdTe focal plane array (FPA) cooled with a Sterling-cooler. The imager operates in 8-10.5 μm (long wave IR, LWIR) spectral region and an image cube with 50 to 200 bands can be acquired rapidly. Spectral images at different wavelengths are obtained by moving the lens along its optical axis. An f/2.38 diffractive lens is used with a focal length of 70 mm at 8 μm. The IFOV is 0.57 mrad which corresponds to an FOV of 10.48°. The spectral resolution of the imager is 0.034 μm at 9 μm. The pixel size is 40×40 μm2 in the FPA. In post processing of image cube data contributions due to wavelengths other than the focused one are removed and a correction to account for the change in magnification due to the motion of the lens is applied to each spectral image. A brief description of the imager, data collection and analysis to characterize the performance of the imager will be presented in this paper.
Confocal Raman spectroscopy and AFM for evaluation of sidewalls in type II superlattice FPAs
NASA Astrophysics Data System (ADS)
Rotter, T. J.; Busani, T.; Rathi, P.; Jaeckel, F.; Reyes, P. A.; Malloy, K. J.; Ukhanov, A. A.; Plis, E.; Krishna, S.; Jaime-Vasquez, M.; Baril, N. F.; Benson, J. D.; Tenne, D. A.
2015-06-01
We propose to utilize confocal Raman spectroscopy combined with high resolution atomic force microscopy (AFM) for nondestructive characterisation of the sidewalls of etched and passivated small pixel (24 μm×24 μm) focal plane arrays (FPA) fabricated using LW/LWIR InAs/GaSb type-II strained layer superlattice (T2SL) detector material. Special high aspect ratio Si and GaAs AFM probes, with tip length of 13 μm and tip aperture less than 7°, allow characterisation of the sidewall morphology. Confocal microscopy enables imaging of the sidewall profile through optical sectioning. Raman spectra measured on etched T2SL FPA single pixels enable us to quantify the non-uniformity of the mesa delineation process.
NASA Astrophysics Data System (ADS)
Amory, V.; Lhémery, A.
2008-02-01
Inspection of irregular components is problematical: maladjustment of transducer shoes to surfaces causes aberrations. Flexible phased-arrays (FPAs) designed at CEA LIST to maximize contact are driven by adapted delay laws to compensate for irregularities. Optimizing FPA requires simulation tools. The behavior of one element computed by FEM is observed at the surface and its radiation experimentally validated. Efforts for one element prevent from simulating a FPA by FEM. A model is proposed where each element behaves as nonuniform source of stresses. Exact and asymptotic formulas for Lamb problem are used as convolution kernels for longitudinal, transverse and head waves; the latter is of primary importance for angle-T-beam inspections.
Noise properties of a corner-cube Michelson interferometer LWIR hyperspectral imager
NASA Astrophysics Data System (ADS)
Bergstrom, D.; Renhorn, I.; Svensson, T.; Persson, R.; Hallberg, T.; Lindell, R.; Boreman, G.
2010-04-01
Interferometric hyperspectral imagers using infrared focal plane array (FPA) sensors have received increasing interest within the field of security and defence. Setups are commonly based upon either the Sagnac or the Michelson configuration, where the former is usually preferred due to its mechanical robustness. However, the Michelson configuration shows advantages in larger FOV due to better vignetting performance and improved signal-to-noise ratio and cost reduction due to relaxation of beamsplitter specifications. Recently, a laboratory prototype of a more robust and easy-to-align corner-cube Michelson hyperspectral imager has been demonstrated. The prototype is based upon an uncooled bolometric FPA in the LWIR (8-14 μm) spectral band and in this paper the noise properties of this hyperspectral imager are discussed.
Development and Demonstration of an Ada Test Generation System
NASA Technical Reports Server (NTRS)
1996-01-01
In this project we have built a prototype system that performs Feasible Path Analysis on Ada programs: given a description of a set of control flow paths through a procedure, and a predicate at a program point feasible path analysis determines if there is input data which causes execution to flow down some path in the collection reaching the point so that tile predicate is true. Feasible path analysis can be applied to program testing, program slicing, array bounds checking, and other forms of anomaly checking. FPA is central to most applications of program analysis. But, because this problem is formally unsolvable, syntactic-based approximations are used in its place. For example, in dead-code analysis the problem is to determine if there are any input values which cause execution to reach a specified program point. Instead an approximation to this problem is computed: determine whether there is a control flow path from the start of the program to the point. This syntactic approximation is efficiently computable and conservative: if there is no such path the program point is clearly unreachable, but if there is such a path, the analysis is inconclusive, and the code is assumed to be live. Such conservative analysis too often yields unsatisfactory results because the approximation is too weak. As another example, consider data flow analysis. A du-pair is a pair of program points such that the first point is a definition of a variable and the second point a use and for which there exists a definition-free path from the definition to the use. The sharper, semantic definition of a du-pair requires that there be a feasible definition-free path from the definition to the use. A compiler using du-pairs for detecting dead variables may miss optimizations by not considering feasibility. Similarly, a program analyzer computing program slices to merge parallel versions may report conflicts where none exist. In the context of software testing, feasibility analysis plays an important role in identifying testing requirements which are infeasible. This is especially true for data flow testing and modified condition/decision coverage. Our system uses in an essential way symbolic analysis and theorem proving technology, and we believe this work represents one of the few successful uses of a theorem prover working in a completely automatic fashion to solve a problem of practical interest. We believe this work anticipates an important trend away from purely syntactic-based methods for program analysis to semantic methods based on symbolic processing and inference technology. Other results demonstrating the practical use of automatic inference is being reported in hardware verification, although there are significant differences between the hardware work and ours. However, what is common and important is that general purpose theorem provers are being integrated with more special-purpose decision procedures to solve problems in analysis and verification. We are pursuina commercial opportunities for this work, and will use and extend the work in other projects we are engaged in. Ultimately we would like to rework the system to analyze C, C++, or Java as a key step toward commercialization.
Modeling Charge Collection in Detector Arrays
NASA Technical Reports Server (NTRS)
Hardage, Donna (Technical Monitor); Pickel, J. C.
2003-01-01
A detector array charge collection model has been developed for use as an engineering tool to aid in the design of optical sensor missions for operation in the space radiation environment. This model is an enhancement of the prototype array charge collection model that was developed for the Next Generation Space Telescope (NGST) program. The primary enhancements were accounting for drift-assisted diffusion by Monte Carlo modeling techniques and implementing the modeling approaches in a windows-based code. The modeling is concerned with integrated charge collection within discrete pixels in the focal plane array (FPA), with high fidelity spatial resolution. It is applicable to all detector geometries including monolithc charge coupled devices (CCDs), Active Pixel Sensors (APS) and hybrid FPA geometries based on a detector array bump-bonded to a readout integrated circuit (ROIC).
Jamison, J M; Fourie, E; Siper, P M; Trelles, M P; George-Jones, Julia; Buxbaum Grice, A; Krata, J; Holl, E; Shaoul, J; Hernandez, B; Mitchell, L; McKay, M M; Buxbaum, J D; Kolevzon, Alexander
2017-05-01
Autism spectrum disorder (ASD) affects individuals across all racial and ethnic groups, yet rates of diagnosis are disproportionately higher for Black and Hispanic children. Caregivers of children with ASD experience significant stressors, which have been associated with parental strain, inadequate utilization of mental health services and lower quality of life. The family peer advocate (FPA) model has been utilized across service delivery systems to provide family-to-family support, facilitate engagement, and increase access to care. This study used a randomized controlled design to examine the efficacy of FPAs in a racially and ethnically diverse sample. Results demonstrate significantly increased knowledge of ASD and reduced levels of stress for caregivers who received the FPA intervention as compared to treatment as usual.
Subelectron readout noise focal plane arrays for space imaging
NASA Astrophysics Data System (ADS)
Atlas, Gene; Wadsworth, Mark
2004-01-01
Readout noise levels of under 1 electron have long been a goal for the FPA community. In the quest to enhance the FPA sensitivity, various approaches have been attempted ranging from the exotic Photo-multiplier tubes, Image Intensifier tubes, Avalanche photo diodes, and now the on-chip avalanche charge amplification technologies from the CCD manufacturers. While these techniques reduce the readout noise, each offers a set of compromises that negatively affect the overall performance of the sensor in parameters such as power dissipation, dynamic range, uniformity or system complexity. In this work, we overview the benefits and tradeoffs of each approach, and introduce a new technique based on ImagerLabs" exclusive HIT technology which promises sub-electron read noise and other benefits without the tradeoffs of the other noise reduction techniques.
Motion-based nonuniformity correction in DoFP polarimeters
NASA Astrophysics Data System (ADS)
Kumar, Rakesh; Tyo, J. Scott; Ratliff, Bradley M.
2007-09-01
Division of Focal Plane polarimeters (DoFP) operate by integrating an array of micropolarizer elements with a focal plane array. These devices have been investigated for over a decade, and example systems have been built in all regions of the optical spectrum. DoFP devices have the distinct advantage that they are mechanically rugged, inherently temporally synchronized, and optically aligned. They have the concomitant disadvantage that each pixel in the FPA has a different instantaneous field of view (IFOV), meaning that the polarization component measurements that go into estimating the Stokes vector across the image come from four different points in the field. In addition to IFOV errors, microgrid camera systems operating in the LWIR have the additional problem that FPA nonuniformity (NU) noise can be quite severe. The spatial differencing nature of a DoFP system exacerbates the residual NU noise that is remaining after calibration, and is often the largest source of false polarization signatures away from regions where IFOV error dominates. We have recently presented a scene based algorithm that uses frame-to-frame motion to compensate for NU noise in unpolarized IR imagers. In this paper, we have extended that algorithm so that it can be used to compensate for NU noise on a DoFP polarimeter. Furthermore, the additional information provided by the scene motion can be used to significantly reduce the IFOV error. We have found a reduction of IFOV error by a factor of 10 if the scene motion is known exactly. Performance is reduced when the motion must be estimated from the scene, but still shows a marked improvement over static DoFP images.
Image quality testing of assembled IR camera modules
NASA Astrophysics Data System (ADS)
Winters, Daniel; Erichsen, Patrik
2013-10-01
Infrared (IR) camera modules for the LWIR (8-12_m) that combine IR imaging optics with microbolometer focal plane array (FPA) sensors with readout electronics are becoming more and more a mass market product. At the same time, steady improvements in sensor resolution in the higher priced markets raise the requirement for imaging performance of objectives and the proper alignment between objective and FPA. This puts pressure on camera manufacturers and system integrators to assess the image quality of finished camera modules in a cost-efficient and automated way for quality control or during end-of-line testing. In this paper we present recent development work done in the field of image quality testing of IR camera modules. This technology provides a wealth of additional information in contrast to the more traditional test methods like minimum resolvable temperature difference (MRTD) which give only a subjective overall test result. Parameters that can be measured are image quality via the modulation transfer function (MTF) for broadband or with various bandpass filters on- and off-axis and optical parameters like e.g. effective focal length (EFL) and distortion. If the camera module allows for refocusing the optics, additional parameters like best focus plane, image plane tilt, auto-focus quality, chief ray angle etc. can be characterized. Additionally, the homogeneity and response of the sensor with the optics can be characterized in order to calculate the appropriate tables for non-uniformity correction (NUC). The technology can also be used to control active alignment methods during mechanical assembly of optics to high resolution sensors. Other important points that are discussed are the flexibility of the technology to test IR modules with different form factors, electrical interfaces and last but not least the suitability for fully automated measurements in mass production.
New focus on advocacy in South Asia. Advocacy for reproductive health: South Asia.
Kapoor, I
1996-01-01
Initiatives like Vision 2000, the International Conference on Population and Development in Cairo, and the Fourth World Conference on Women in Beijing have focused attention on the activities of regional family planning associations (FPAs) in South Asia. These activities include male acceptance of the responsibility for family life, youth involvement in program design and implementation, the promotion of gender equality, and increased public awareness about the value of the female child. The Beijing conference also directed attention to the problem of not allocating resources to problems recognized by governments. In the South Asia region funding levels have been falling, which impacts the maintenance of current programs. The South Asia Regional Bureau began to coordinate an information, education, and communication (IEC) and Advocacy Working Group in the region with the participation of IEC officers from all regional FPAs. The group will be planning IEC and advocacy activities based on the regional FPAs' goals and aspirations. The IEC and advocacy activities will be examined to identify existing skills and experiences of group participants. The group will also try to identify the activities of each FPA. The information gathered will point out the similarities in IEC and advocacy activities serving as a common ground for the region. Problems of IEC and advocacy comprise their subordinate structure and the failure to evaluate to show the impact of the activities. Better planning and organization and more holistic evaluation of program components should be achieved. The group will be self-directed responding to the IEC and advocacy needs, while also developing the professional and personal capacity of FPA staff to meet these needs.
Buffer strip design for protecting water quality and fish habitat
DOE Office of Scientific and Technical Information (OSTI.GOV)
Belt, G.H.; O'Laughlin, J.
1994-04-01
Buffer strips are protective areas adjacent to streams or lakes. Among other functions, they protect water quality and fish habitat. A typical buffer strip is found in western Oregon, where they are called Riparian Management Areas (RMAs). The authors use the term buffer strip to include functional descriptions such as filter, stabilization, or leave strips, and administrative designations such as Idaho's Stream Protection Zone (SPZ), Washington's Riparian Management Zone (RMZ), and the USDA Forest Service's Streamside Management Zone (SMZ). They address water quality and fishery protective functions of buffer strips on forestlands, pointing out improvements in buffer strip design possiblemore » through research or administrative changes. Buffer strip design requirements found in some western Forest Practices Act (FPA) regulations are also compared and related to findings in the scientific literature.« less
Scene-based nonuniformity correction for airborne point target detection systems.
Zhou, Dabiao; Wang, Dejiang; Huo, Lijun; Liu, Rang; Jia, Ping
2017-06-26
Images acquired by airborne infrared search and track (IRST) systems are often characterized by nonuniform noise. In this paper, a scene-based nonuniformity correction method for infrared focal-plane arrays (FPAs) is proposed based on the constant statistics of the received radiation ratios of adjacent pixels. The gain of each pixel is computed recursively based on the ratios between adjacent pixels, which are estimated through a median operation. Then, an elaborate mathematical model describing the error propagation, derived from random noise and the recursive calculation procedure, is established. The proposed method maintains the characteristics of traditional methods in calibrating the whole electro-optics chain, in compensating for temporal drifts, and in not preserving the radiometric accuracy of the system. Moreover, the proposed method is robust since the frame number is the only variant, and is suitable for real-time applications owing to its low computational complexity and simplicity of implementation. The experimental results, on different scenes from a proof-of-concept point target detection system with a long-wave Sofradir FPA, demonstrate the compelling performance of the proposed method.
Status of LWIR HgCdTe infrared detector technology
NASA Technical Reports Server (NTRS)
Reine, M. B.
1990-01-01
The performance requirements that today's advanced Long Wavelength Infrared (LWIR) focal plane arrays place on the HgCdTe photovoltaic detector array are summarized. The theoretical performance limits for intrinsic LWIR HgCdTe detectors are reviewed as functions of cutoff wavelength and operating temperature. The status of LWIR HgCdTe photovoltaic detectors is reviewed and compared to the focal plane array (FPA) requirements and to the theoretical limits. Emphasis is placed on recent data for two-layer HgCdTe PLE heterojunction photodiodes grown at Loral with cutoff wavelengths ranging between 10 and 19 microns at temperatures of 70 to 80 K. Development trends in LWIR HgCdTe detector technology are outlined, and conclusions are drawn about the ability for photovoltaic HgCdTe detector arrays to satisfy a wide variety of advanced FPA array applications.
The 640 × 512 LWIR type-II superlattice detectors operating at 110 K
NASA Astrophysics Data System (ADS)
Tan, Bi-Song; Zhang, Chuan-Jie; Zhou, Wen-Hong; Yang, Xiao-Jie; Wang, Guo-Wei; Li, Yun-Tao; Ding, Yan-Yan; Zhang, Zhou; Lei, Hua-Wei; Liu, Wei-Hua; Du, Yu; Zhang, Li-Fang; Liu, Bin; Wang, Li-Bao; Huang, Li
2018-03-01
The type-II InAs/GaSb superlattices (T2SLs)-based 640 × 512 long wavelength infrared (LWIR) Focal Plane Array (FPA) detector with15 μm pitch and 50% cut-off wavelength of 10.5 μm demonstrates a peak quantum efficiency of 38.6% and peak detectivity of 1.65 × 1011 cm Hz1/2 W-1 at 8.1 μm, high pixel operability of 99.5% and low responsivity non-uniformity of 2.69% at 80 K. The FPA exhibits clear infrared imaging at 110 K and diffusion-limited dark current densities below Tennant's 'Rule07' at temperature above 100 K, which is attributed to the efficient suppression of diffusion dark current and surface leak current by introducing M-structure barrier and double hetero-structure passivation layers.
Li, Yantao; Hu, Weida; Ye, Zhenhua; Chen, Yiyu; Chen, Xiaoshuang; Lu, Wei
2017-04-01
Mercury cadmium telluride is the standard material to fabricate high-performance infrared focal plane array (FPA) detectors. However, etch-induced damage is a serious obstacle for realizing highly uniform and damage-free FPA detectors. In this Letter, the high signal-to-noise ratio and high spatial resolution scanning photocurrent microscopy (SPCM) is used to characterize the dry etch-induced inversion layer of vacancy-doped p-type Hg1-xCdxTe (x=0.22) material under different etching temperatures. It is found that the peak-to-peak magnitude of the SPCM profile decreases with a decrease in etching temperature, showing direct proof of controlling dry etch-induced type conversion. Our work paves the way toward seeking optimal etching processes in large-scale infrared FPAs.
High-Performance LWIR Superlattice Detectors and FPA Based on CBIRD Design
NASA Technical Reports Server (NTRS)
Soibel, Alexander; Nguyen, Jean; Rafol, Sir B.; Liao, Anna; Hoeglund, Linda; Khoshakhlagh, Arezou; Keo, Sam A.; Mumolo, Jason M.; Liu, John; Ting, David Z.-Y.;
2011-01-01
We report our recent efforts on advancing of antimonide superlattice based infrared photodetectors and demonstration of focal plane arrays based on a complementary barrier infrared detector (CBIRD) design. By optimizing design and growth condition we succeeded to reduce the operational bias of CBIRD single pixel detector without increase of dark current or degradation of quantum efficiency. We demonstrated a 1024x1024 pixel long-wavelength infrared focal plane array utilizing CBIRD design. An 11.5 micrometer cutoff focal plane without anti-reflection coating has yielded noise equivalent differential temperature of 53 mK at operating temperature of 80 K, with 300 K background and cold-stop. Imaging results from a recent 10 micrometer cutoff focal plane array are also presented. These results advance state-of-the art of superlattice detectors and demonstrated advantages of CBIRD architecture for realization of FPA.
High-Performance LWIR Superlattice Detectors and FPA Based on CBIRD Design
NASA Technical Reports Server (NTRS)
Soibel, Alexander; Nguyen, Jean; Rafol, Sir B.; Liao, Anna; Hoeglund, Linda; Khoshakhlagh, Arezou; Keo, Sam A.; Mumolo, Jason M.; Liu, John; Ting, David Z.-Y.;
2011-01-01
We report our recent efforts on advancing of antimonide superlattice based infrared photodetectors and demonstration of focal plane arrays based on a complementary barrier infrared detector (CBIRD) design. By optimizing design and growth condition we succeeded to reduce the operational bias of CBIRD single pixel detector without increase of dark current or degradation of quantum efficiency. We demonstrated a 1024x1024 pixel long-waveleng thinfrared focal plane array utilizing CBIRD design. An 11.5 micrometer cutoff focal plane without anti-reflection coating has yielded noise equivalent differential temperature of 53 mK at operating temperature of 80 K, with 300 K background and cold-stop. Imaging results from a recent 10 micrometer cutoff focal plane array are also presented. These results advance state-of-the art of superlattice detectors and demonstrated advantages of CBIRD architecture for realization of FPA.
Improvements of MCT MBE Growth on GaAs
NASA Astrophysics Data System (ADS)
Ziegler, J.; Wenisch, J.; Breiter, R.; Eich, D.; Figgemeier, H.; Fries, P.; Lutz, H.; Wollrab, R.
2014-08-01
In recent years, continuous progress has been published in the development of HgCdTe (MCT) infrared (IR) focal plane arrays (FPAs) fabricated by molecular beam epitaxy on GaAs substrates. In this publication, further characterization of the state-of-the art 1280 × 1024 pixel, 15- μm pitch detector fabricated from this material in both the mid-wavelength (MWIR) and long-wavelength (LWIR) IR region will be presented. For MWIR FPAs, the percentage of defective pixel remains below 0.5% up to an operating temperature ( T OP) of around 100 K. For the LWIR FPA, an operability of 99.25% was achieved for a T OP of 76 K. Additionally, the beneficial effect of the inclusion of MCT layers with a graded composition region was investigated and demonstrated on current-voltage ( IV) characteristics on test diodes in a MWIR FPA.
Quantum well infrared photodetector simultaneously working in the two atmospheric windows
NASA Astrophysics Data System (ADS)
Huo, Y. H.; Ma, W. Q.; Zhang, Y. H.; Chong, M.; Yang, T.; Chen, L. H.; Shi, Y. L.
2009-07-01
We have demonstrated a dual-band quantum well infrared photodetector (QWIP) exhibiting simultaneous photoresponse both in the mid and the long wavelength atmospheric windows of 3-5 μm and of 8-12 μm, but the device only has two ohmic contacts. The structure of the device was achieved by sequentially growing a mid wavelength part (MWQWIP) followed by a long wavelength part (LWQWIP) separated by an n+ layer. Comparing with the conventional dual-band QWIP device utilizing three ohmic contacts, our QWIP is promising to greatly facilitate the two-color focal plane array (FPA) fabrication by reducing the number of the indium bump per pixel from three to one just like a monochromatic FPA fabrication; another advantage may be that this QWIP FAP boasts two-color detection capability while only using a monochromatic readout integrated circuit.
Pelican: SCD's 640 × 512/15 μm pitch InSb detector
NASA Astrophysics Data System (ADS)
Oiknine Schlesinger, J.; Calahorra, Z.; Uri, E.; Shick, O.; Fishman, T.; Shtrichman, I.; Sinbar, E.; Nahum, V.; Kahanov, E.; Shlomovich, B.; Hasson, S.; Fishler, N.; Chen, D.; Markovitz, T.
2007-04-01
Over the last decade, SCD has developed and manufactured high quality InSb Focal Plane Arrays (FPAs), that are currently used in different applications worldwide. SCD's production line includes InSb FPAs with mid format (320x256 elements), and large format (640x512 elements), all available in various packaging configurations, including fully integrated Detector-Dewar-Cooler Assemblies (DDCA). Many of SCD's products are fully customized for customers' needs, and are optimized for each application with respect to the weight, power, size, and performance. In 2006, SCD has added to its broad InSb product portfolio the new "Pelican" detector family. All Pelican detectors include a large format 640×512 InSb FPA with 15μm pitch, which is based on the FLIR/Indigo ISC0403 Readout Integrated Circuit (ROIC). Due to its small size, the Pelican FPA fits in any mid format Dewar, enabling upgrading of mid format systems with higher spatial resolution due to its good MTF. This work presents the high performance of Pelican products. As achieved in all SCD's InSb DDC's, the Pelican detectors demonstrate high uniformity and correctability (residual non uniformity less than 0.05% std/DR) and remarkable operability (typically better than 99.9%). The Pelican FPA can be integrated in various DDCA configurations as per application needs, such as light weight, low power and compact form for hand held imagers, or a rigid configuration for environmentally demanding operating and storage conditions.
Kimble, Christopher J; Johnson, David M; Winter, Bruce A; Whitlock, Sidney V; Kressin, Kenneth R; Horne, April E; Robinson, Justin C; Bledsoe, Jonathan M; Tye, Susannah J; Chang, Su-Youne; Agnesi, Filippo; Griessenauer, Christoph J; Covey, Daniel; Shon, Young-Min; Bennet, Kevin E; Garris, Paul A; Lee, Kendall H
2009-01-01
The Wireless Instantaneous Neurotransmitter Concentration Sensing System (WINCS) measures extracellular neurotransmitter concentration in vivo and displays the data graphically in nearly real time. WINCS implements two electroanalytical methods, fast-scan cyclic voltammetry (FSCV) and fixed-potential amperometry (FPA), to measure neurotransmitter concentrations at an electrochemical sensor, typically a carbon-fiber microelectrode. WINCS comprises a battery-powered patient module and a custom software application (WINCSware) running on a nearby personal computer. The patient module impresses upon the electrochemical sensor either a constant potential (for FPA) or a time-varying waveform (for FSCV). A transimpedance amplifier converts the resulting current to a signal that is digitized and transmitted to the base station via a Bluetooth radio link. WINCSware controls the operational parameters for FPA or FSCV, and records the transmitted data stream. Filtered data is displayed in various formats, including a background-subtracted plot of sequential FSCV scans - a representation that enables users to distinguish the signatures of various analytes with considerable specificity. Dopamine, glutamate, adenosine and serotonin were selected as analytes for test trials. Proof-of-principle tests included in vitro flow-injection measurements and in vivo measurements in rat and pig. Further testing demonstrated basic functionality in a 3-Tesla MRI unit. WINCS was designed in compliance with consensus standards for medical electrical device safety, and it is anticipated that its capability for real-time intraoperative monitoring of neurotransmitter release at an implanted sensor will prove useful for advancing functional neurosurgery.
Organic photodetectors and their applications for hemispherical imaging focal plane arrays
NASA Astrophysics Data System (ADS)
Xu, Xin
Softness of organic semiconducting materials holds promise for fabricating optoelectronic devices and circuits on nonplanar surfaces. The low growth temperature of organic small molecules also allows for the deposition onto a plastic substrate, which has the potential for significantly lowering the fabrication cost. However, the softness of organic small molecules can become problematic. Most of the well-established patterning techniques in the semiconductor industry are not suitable for patterning organic-based devices. High temperatures, high pressures, exposure to wet chemicals or high-energy particles that may exist in the conventional patterning approaches can damage the organic active layers. Although methods for large area patterning of organic electronics onto planar substrates have been demonstrated, in this thesis we extend the patterning capability to curved surfaces by using a novel three dimensional (3D) cold welding method. We use 3D cold welding to fabricate a hemispherical focal plane array (FPA) for compact imaging systems that mimic the architecture and function of the human eye. A 10 kilopixel organic photodetector FPA is thus demonstrated on a 1 cm radius hemisphere. By patterning brittle yet transparent indium tin oxide anodes instead of semitransparent metal anodes on the hemispheres, the detectivity of the FPA is improved. We introduce a sensitive hybrid photodetector employing a carbon nanotube/small molecular organic junction with a broad spectral response extending into the near infrared. Since the photodetector array shows an increased noise level with the array size, integrated arrays of organic photodetectors and thin film transistors as switches are demonstrated.
Kimble, Christopher J.; Johnson, David M.; Winter, Bruce A.; Whitlock, Sidney V.; Kressin, Kenneth R.; Horne, April E.; Robinson, Justin C.; Bledsoe, Jonathan M.; Tye, Susannah J.; Chang, Su-Youne; Agnesi, Filippo; Griessenauer, Christoph J.; Covey, Daniel; Shon, Young-Min; Bennet, Kevin E.; Garris, Paul A.; Lee, Kendall H.
2010-01-01
The Wireless Instantaneous Neurotransmitter Concentration Sensing System (WINCS) measures extracellular neurotransmitter concentration in vivo and displays the data graphically in nearly real time. WINCS implements two electroanalytical methods, fast-scan cyclic voltammetry (FSCV) and fixed-potential amperometry (FPA), to measure neurotransmitter concentrations at an electrochemical sensor, typically a carbon-fiber microelectrode. WINCS comprises a battery-powered patient module and a custom software application (WINCSware) running on a nearby personal computer. The patient module impresses upon the electrochemical sensor either a constant potential (for FPA) or a time-varying waveform (for FSCV). A transimpedance amplifier converts the resulting current to a signal that is digitized and transmitted to the base station via a Bluetooth® radio link. WINCSware controls the operational parameters for FPA or FSCV, and records the transmitted data stream. Filtered data is displayed in various formats, including a background-subtracted plot of sequential FSCV scans—a representation that enables users to distinguish the signatures of various analytes with considerable specificity. Dopamine, glutamate, adenosine and serotonin were selected as analytes for test trials. Proof-of-principle tests included in vitro flow-injection measurements and in vivo measurements in rat and pig. Further testing demonstrated basic functionality in a 3-Tesla MRI unit. WINCS was designed in compliance with consensus standards for medical electrical device safety, and it is anticipated that its capability for real-time intraoperative monitoring of neurotransmitter release at an implanted sensor will prove useful for advancing functional neurosurgery. PMID:19963865
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-04
... (FPA), proposing to study the feasibility of the Microturbine Hydrokinetic River-In-Stream Energy.... Applicant Contact: Mr. Steven M. Selvaggio, Whitestone Power and Communications, P.O. Box 1630, Delta...
Fluid/Gravity Correspondence, Second Order Transport and Gravitational Anomaly***
NASA Astrophysics Data System (ADS)
Megías, Eugenio; Pena-Benitez, Francisco
2014-03-01
We study the transport properties of a relativistic fluid affected by chiral and gauge-gravitational anomalies. The computation is performed in the framework of the fluid/gravity correspondence for a 5 dim holographic model with Chern-Simons terms in the action. We find new anomalous and non anomalous transport coefficients, as well as new contributions to the existing ones coming from the mixed gauge-gravitational anomaly. Consequences for the shear waves dispersion relation are analyzed. Talk given by E. Megías at the International Nuclear Physics Conference INPC 2013, 2-7 June 2013, Firenze, Italy.Supported by Plan Nacional de Altas Energías (FPA2009-07908, FPA2011-25948), Spanish MICINN Consolider-Ingenio 2010 Programme CPAN (CSD2007-00042), Comunidad de Madrid HEP-HACOS S2009/ESP-1473, Spanish MINECO's Centro de Excelencia Severo Ochoa Program (SEV-2012-0234, SEV-2012-0249), and the Juan de la Cierva Program.
Large-Format Dual-Counter Pixelated X-Ray Detector Platform: Phase II Final Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lee, Adam; Williams, George; Huntington, Andrew
2016-10-10
Within the program, a Voxtel led team demonstrated both prototype (48 x 48, 130-μm pitch, VX-798) and full-format (192 x 192, 100-μm pitch, VX-810) versions of a high-dynamic-range, x-ray photon-counting (HDR-XPC) sensor. Within the program the following tasks were completed: 1) integration and evaluation of the VX-798 prototype camera at the Advanced Photon Source beamline at Argonne National Labs; 2) the design, simulation, and fabrication of the full-format VX-810 ROIC was completed; 3) fabrication of thick, fully depleted silicon photodiodes optimized for x-ray photon collection; 4) hybridization of the VX-810 ROIC to the photodiode array in the creation of themore » optically sensitive FPA (FPA), and 4) development of an evaluation camera to enable electrical and optical characterization of the sensor.« less
Simulation of sampling effects in FPAs
NASA Astrophysics Data System (ADS)
Cook, Thomas H.; Hall, Charles S.; Smith, Frederick G.; Rogne, Timothy J.
1991-09-01
The use of multiplexers and large focal plane arrays in advanced thermal imaging systems has drawn renewed attention to sampling and aliasing issues in imaging applications. As evidenced by discussions in a recent workshop, there is no clear consensus among experts whether aliasing in sensor designs can be readily tolerated, or must be avoided at all cost. Further, there is no straightforward, analytical method that can answer the question, particularly when considering image interpreters as different as humans and autonomous target recognizers (ATR). However, the means exist for investigating sampling and aliasing issues through computer simulation. The U.S. Army Tank-Automotive Command (TACOM) Thermal Image Model (TTIM) provides realistic sensor imagery that can be evaluated by both human observers and TRs. This paper briefly describes the history and current status of TTIM, explains the simulation of FPA sampling effects, presents validation results of the FPA sensor model, and demonstrates the utility of TTIM for investigating sampling effects in imagery.
Draffehn, Sören; Kumke, Michael U
2016-05-02
Nowadays, the encapsulation of therapeutic compounds in so-called carrier systems is a very smart method to achieve protection as well as an improvement of their temporal and spatial distribution. After the successful transport to the point of care, the delivery has to be released under controlled conditions. To monitor the triggered release from the carrier, we investigated different fluorescent probes regarding their response to the pH-induced collapse of pH-sensitive liposomes (pHSLip), which occurs when the environmental pH falls below a critical value. Depending on the probe, the fluorescence decay time as well as fluorescence anisotropy can be used equally as key parameters for monitoring the collapse. Especially the application of a fluorescein labeled fatty acid (fPA) enabled the monitoring of the pHSLips collapse and the pH of its microenvironment simultaneously without interference. Varying the pH in the range of 3 < pH < 9, anisotropy data revealed the critical pH value at which the collapse of the pHSLips occurs. Complementary methods, e.g., fluorescence correlation spectroscopy and dynamic light scattering, supported the analysis based on the decay time and anisotropy. Additional experiments with varying incubation times yielded information on the kinetics of the liposomal collapse.
Colombo opens door for FPA action.
1979-01-01
In a 36-point declaration adopted unanimously by the Colombo Conference on Population and Development, the voluntary sector in population was recognized as an equal partner with governments and international agencies. The Conference also called for international assistance for population activities to be increased to an annual target of 1 billion dollars by 1984. Consequently, Family Planning Associations are being encouraged to make contact with parliamentarians who attended the Conference and to support their work in the population field. The Conference, held from August 28-September 1, 1979 in Colombo, Sri Lanka, brought together parliamentarians from both developed and developing nations. Included among the Conference's recommendations for action were the following: 1) the integration of population and development as a key issue in the International Development Strategy to be adopted for the 1980's; and 2) a United Nations World Population Conference in 1984 to review progress made over the 10 years since the Bucharest Conference and to propose further action.
NASA Technical Reports Server (NTRS)
Wang, Zhipeng; Xiong, Xiaoxiong
2017-01-01
The MODIS instruments aboard Terra and Aqua satellites are radiometrically calibrated on-orbit with a set of onboard calibrators (OBC) including a solar diffuser (SD), a blackbody (BB) and a space view (SV) port through which the detectors can view the dark space. As a whisk-broom scanning spectroradiometer, thirty-six MODIS spectral bands are assembled in the along-scan direction on four focal plane assemblies (FPA). These bands capture images of the same target sequentially with the motion of a scan mirror. Then the images are co-registered on board by delaying appropriate band dependent amount of time depending on the band locations on the FPA. While this co-registration mechanism is functioning well for the "far field" remote targets such as Earth view (EV) scenes or the Moon, noticeable band-to-band misregistration in the along-scan direction has been observed for near field targets, in particular the OBCs. In this paper, the misregistration phenomenon is presented and analyzed. It is concluded that the root cause of the misregistration is that the rotating element of the instrument, the scan mirror, is displaced from the focus of the telescope primary mirror. The amount of the misregistration is proportional to the band location on the FPA and is inversely proportional to the distance between the target and the scan mirror. The impact of this misregistration to the calibration of MODIS bands is discussed. In particular, the calculation of the detector gain coefficient m1 of bands 8-16 (412 nm 870 nm) is improved by up to 1.5% for Aqua MODIS.
Durzan, Don J
2012-09-01
Cell fate, development timing and occurrence of reproductive versus apomictic development in gymnosperms are shown to be influenced by culture conditions in vitro. In this study, female parthenogenetic apomixis (fPA), androsporogenetic parthenogenesis (mAP) and progenesis were demonstrated using embryonal initials of Araucaria angustifolia in scaled-up cell suspensions passing through a single-cell bottleneck in darkness and in an artificial sporangium (AS). Expression was based on defined nutrition, hormones and feedforward-adaptive feedback process controls at 23-25 °C and in darkness. In fPA, the nucleus of an embryonal initial undergoes endomitosis and amitosis, forming a diploid egg-equivalent and an apoptotic ventral canal nucleus in a transdifferentiated archegonial tube. Discharge of egg-equivalent cells as parthenospores and their dispersal into the aqueous culture medium were followed by free-nuclear conifer-type proembryogenesis. This replaced the plesiomorphic and central features of proembryogenesis in Araucariaceae. Protoplasmic fusions of embryonal initials were used to reconstruct heterokaryotic expressions of fPA in multiwell plates. In mAP, restitutional meiosis (automixis) was responsible for androsporogenesis and the discharge of monads, dyads, tetrads and polyads. In a display of progenesis, reproductive development was brought to an earlier ontogenetic stage and expressed by embryonal initials. Colchicine increased polyploidy, but androspore formation became aberrant and fragmented. Aberrant automixis led to the formation of chromosomal bouquets, which contributed to genomic silencing in embryonal initials, cytomixis and the formation of pycnotic micronucleated cells. Dispersal of female and male parthenospores displayed heteromorphic asexual heterospory in an aqueous environment.
November campaign to increase pill awareness.
1993-01-01
70% of respondents in a survey of women using oral contraceptives (OCs) reported that they have forgotten to take at least 1 OC pill. Insufficient information on taking OCs is responsible for such mistakes. Many women calling the hotline of the UK Family Planning Association (FPA) do not really understand how OCs work so they do not actually realize the risks of forgetting to take pills. The UK's Department of Health, FPA, the Royal Pharmaceutical Association, the Health Education Authority, and health agencies in Scotland, Wales, and Northern Ireland have joined together to reduce this ignorance about the significance of not taking pills among the 3 million women in the UK who use OCs. This OC initiative is part of the Pharmacy Healthcare Scheme. 70% of pharmacists in a recent survey claim that customers ask them about contraception, particularly OCs, at least once a month and as often as once a week. Since pharmacists work in the community and are highly trained health professionals, they are in a good position to distribute advice and information. FPA had developed an information pamphlet and poster for the Pharmacy Healthcare Scheme campaign. It plans on distributing more than 500,000 copies to the 13,000 community pharmacies in the UK in November 1993. A briefing sheet to assist pharmacists with doling out advice and information on OCs will accompany the copies. The Scheme also is targeting hospital pharmacies. This initiative hopes to increase awareness about the danger of missing pills, to respond to common questions about OCs, and to encourage women to seek more information about OCs form the pharmacist.
Large format 15μm pitch XBn detector
NASA Astrophysics Data System (ADS)
Karni, Yoram; Avnon, Eran; Ben Ezra, Michael; Berkowitz, Eyal; Cohen, Omer; Cohen, Yossef; Dobromislin, Roman; Hirsh, Itay; Klin, Olga; Klipstein, Philip; Lukomsky, Inna; Nitzani, Michal; Pivnik, Igor; Rozenberg, Omer; Shtrichman, Itay; Singer, Michael; Sulimani, Shay; Tuito, Avi; Weiss, Eliezer
2014-06-01
Over the past few years, a new type of High Operating Temperature (HOT) photon detector has been developed at SCD, which operates in the blue part of the MWIR atmospheric window (3.4 - 4.2 μm). This window is generally more transparent than the red part of the MWIR window (4.4 - 4.9 μm), and thus is especially useful for mid and long range applications. The detector has an InAsSb active layer and is based on the new "XBn" device concept, which eliminates Generation-Recombination dark current and enables operation at temperatures of 150K or higher, while maintaining excellent image quality. Such high operating temperatures reduce the cooling requirements of Focal Plane Array (FPA) detectors dramatically, and allow the use of a smaller closed-cycle Stirling cooler. As a result, the complete Integrated Detector Cooler Assembly (IDCA) has about 60% lower power consumption and a much longer lifetime compared with IDCAs based on standard InSb detectors and coolers operating at 77K. In this work we present a new large format IDCA designed for 150K operation. The 15 μm pitch 1280×1024 FPA is based on SCD's XBn technology and digital Hercules ROIC. The FPA is housed in a robust Dewar and is integrated with Ricor's K508N Stirling cryo-cooler. The IDCA has a weight of ~750 gram and its power consumption is ~ 5.5 W at a frame rate of 100Hz. The Mean Time to Failure (MTTF) of the IDCA is more than 20,000 hours, greatly facilitating 24/7 operation.
The performance of DC restoration function for MODIS thermal emissive bands
NASA Astrophysics Data System (ADS)
Wang, Zhipeng; Xiong, Xiaoxiong Jack; Shrestha, Ashish
2017-09-01
The DC restore (DCR) process of MODIS instrument maintains the output of a detector at focal plane assembly (FPA) within the dynamic range of subsequent analog-to-digital converter, by adding a specific offset voltage to the output. The DCR offset value is adjusted per scan, based on the comparison of the detector response in digital number (DN) collected from the blackbody (BB) view with target DN saved as an on-board look-up table. In this work, the MODIS DCR mechanism is revisited, with the trends of DCR offset being provided for thermal emissive bands (TEB). Noticeable changes have been occasionally found which coincide with significant detector gain change due to various instrumental events such as safe-mode anomaly or FPA temperature fluctuation. In general, MODIS DCR functionality has been effective and the change of DCR offset has no impact to the quality of MODIS data. One exception is the Earth view (EV) data saturation of Aqua MODIS LWIR bands 33, 35 ad 36 during BB warm-up cool-down (WUCD) cycle which has been observed since 2008. The BB view of their detectors saturate when the BB temperature is above certain threshold so the DCR cannot work as designed. Therefore, the dark signal DN fluctuates with the cold FPA (CFPA) temperature and saturate for a few hours per WUCD cycle, which also saturate the EV data sector within the scan. The CFPA temperature fluctuation peaked in 2012 and has been reduced in recent years and the saturation phenomenon has been easing accordingly. This study demonstrates the importance of DCR to data generation.
Rab, Anna; Dallinger, Susanne; Polak, Kaija; Pleiner, Johannes; Polska, Elzbieta; Wolzt, Michael; Schmetterer, Leopold
2004-05-01
There is evidence that hyperinsulinemia may stimulate endothelin-1 (ET-1) generation or release, which may affect diabetic vascular complications. BQ-123, a specific ET(A) receptor antagonist, was used to investigate if insulin-induced vascular effects are influenced by an acute ET-1 release. Two randomized, placebo-controlled, double-blind, cross-over studies were performed. In protocol 1, 12 healthy subjects received, on separate study days, infusions of BQ-123 (60 microg/min for 30 min) during placebo clamp conditions, BQ-123 during euglycemic hyperinsulinemia (3 mU/kg/min for 390 min), or placebo during euglycemic hyperinsulinemia. Fundus pulsation amplitude (FPA) was measured to assess pulsatile choroidal blood flow, and mean flow velocity (MFV) of the ophtalmic artery was measured by color Doppler imaging. In protocol 2, eight healthy subjects received, on separate study days, intra-arterial infusions of BQ-123 (32 microg/min for 120 min) during placebo or insulin clamp. Forearm blood flow was measured with bilateral plethysmography, expressing the ratio of responses in the intervention arm and in the control arm. Insulin alone increased FPA (+10%, p < 0.001) and forearm blood flow (+19%). BQ-123 increased FPA, MFV, and forearm blood flow ratio in the absence and presence of exogenous insulin, but this effect was not different between normo- and hyperinsulinemic conditions. ET-1 plasma concentrations were not affected by insulin. In conclusion, these data do not support the concept that hyperinsulinemia increases ET-1 generation in healthy subjects. Our results, however, cannot necessarily be extrapolated to diabetic and obese subjects.
Polska, Elzbieta; Luksch, Alexandra; Ehrlich, Paulina; Sieder, Anna; Schmetterer, Leopold
2002-04-01
Two laser based methods for the assessment of ocular hemodynamics in humans have been investigated: laser Doppler flowmetry (LDF) and laser interferometric measurement of fundus pulsation amplitude (FPA). When the laser with either of the two methods is focused onto the fovea it is obvious that only choroidal blood flow contributes to the signals. When the laser is, however, directed to other parts of the retina the situation is more complex. Whereas the retina shows a pronounced vasoconstrictor response to systemic hyperoxia the effect in the choroid is small. We therefore investigated the effect of 100% O2 breathing on results as obtained with the above mentioned techniques at different fundus locations. Twelve healthy subjects were included. Four 15-minutes 100% O2 breathing periods were scheduled for each subject. During two of these breathing periods LDF was performed at the fovea (ChBFf) and at a fundus location approximately 7.5 degrees nasally to the fovea (ChBFp), respectively. During the other two periods FPA was assessed at the same fundus locations (FPAf, FPAp). ChBFf tended to decrease during 100% oxygen breathing (6 +/- 4%), but this effect was not significant. The decrease in ChBFp (10 +/- 4%), was comparable. FPAf (10 +/- 2%; P < 0.001) and FPAp (13 +/- 2%; P < 0.001) decreased significantly during systemic hyperoxia, but again there was no difference in the response obtained at the two fundus locations. When LDF and FPA are applied at the peripheral retina the obtained signal is mainly influenced by the choroidal circulation.
In situ longitudinal pre-stretch in the human femoropopliteal artery.
Kamenskiy, Alexey; Seas, Andreas; Bowen, Grant; Deegan, Paul; Desyatova, Anastasia; Bohlim, Nick; Poulson, William; MacTaggart, Jason
2016-03-01
In situ longitudinal (axial) pre-stretch (LPS) plays a fundamental role in the mechanics of the femoropopliteal artery (FPA). It conserves energy during pulsation and prevents buckling of the artery during limb movement. We investigated how LPS is affected by demographics and risk factors, and how these patient characteristics associate with the structural and physiologic features of the FPA. LPS was measured in n=148 fresh human FPAs (14-80 years old). Mechanical properties were characterized with biaxial extension and histopathological characteristics were quantified with Verhoeff-Van Gieson Staining. Constitutive modeling was used to calculate physiological stresses and stretches which were then analyzed in the context of demographics, risk factors and structural characteristics. Age had the strongest negative effect (r=-0.812, p<0.01) on LPS and could alone explain 66% of LPS variability. Male gender, higher body mass index, hypertension, diabetes, coronary artery disease, dyslipidemia and tobacco use had negative effects on LPS, but only the effect of tobacco was not associated with aging. FPAs with less pre-stretch had thicker medial layers, but thinner intramural elastic fibers with less dense and more fragmented external elastic laminae. Elastin degradation was associated with decreased physiological tethering force and longitudinal stress, while circumferential stress remained constant. FPA wall pathology was negatively associated with LPS (r=-0.553, p<0.01), but the effect was due primarily to aging. LPS in the FPA may serve as an energy reserve for adaptive remodeling. Reduction of LPS due to degradation and fragmentation of intramural longitudinal elastin during aging can be accelerated in tobacco users. This work studies in situ longitudinal pre-stretch (LPS) in the human femoropopliteal artery. LPS has a fundamental role in arterial mechanics, but is rather poorly studied due to lack of direct in vivo measurement method. We have investigated LPS in the n=148 human femoropopliteal arteries in the context of subject demographics and risk factors, and structural and physiologic characteristics of the artery. Our results demonstrate that LPS reduces with age due to degradation and fragmentation of intramural elastin. LPS may serve as an energy reserve for adaptive remodeling, and reduction of LPS can be accelerated in tobacco users. Copyright © 2016 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
Chapinal, Núria; Elkin, Brett T; Joly, Damien O; Schumaker, Brant A; Stephen, Craig
2012-08-01
The objective of this study was to estimate agreement between the caudal fold test (CFT) and different serological tests for the detection of Mycobacterium bovis infection in bison by using prevalence-adjusted bias-adjusted kappa (PABAK). A total of 212 of wild wood bison from Wood Buffalo National Park were tested with the CFT as well as several serological tests: fluorescent polarization assay (FPA), multiantigen print immunoassay (MAPIA), rapid lateral-flow test (RT) and dual path platform test (DPP). For RT, 3 variations were conducted using 30μl of serum (RT 30), 20μl of serum (RT 20) and 20μl of serum considering only a strong reaction as positive (RT 20 ST). The McNemar's χ(2) test was conducted to assess whether the proportion of positive test results to 2 different tests differed. Two measures of agreement between pair of tests were estimated: the Cohen's kappa statistic and PABAK. The apparent prevalence of tuberculosis in the sampled animals varied depending on the diagnostic test from 6.1% (FPA and DPP) to 47.2% (CFT). The prevalence estimated by CFT differed from the prevalence estimated by the other tests, whereas the prevalence estimated by FPA, MAPIA, RT 20 ST and DPP were not significantly different. The kappa and PABAK estimates calculated between CFT and the rest of the tests suggested poor to slight agreement between tests (k and PABAK<0.25 in all cases). The PABAK estimates for the pairwise combinations among serological tests were numerically greater than the kappa estimates (and significantly greater when FPA was compared to the rest of serological tests), and suggested substantial to almost perfect agreement (PABAK>0.75 in all cases). The disagreement between the skin and serological tests for the detection of M. bovis infection could be partly because the tests measure different immunological responses (cell-mediated vs. humoral) that are predominant at different stages of the infection, and partly due to inaccuracy of the tests. Further research is needed to evaluate the accuracy of diagnostic tests in order to establish a reliable case definition, combining different tests, to be used in the surveillance and control of tuberculosis in free-ranging bison populations. Copyright © 2012 Elsevier B.V. All rights reserved.
New γ -radiation screening procedures of infrared focal plane arrays (IR FPA)
NASA Astrophysics Data System (ADS)
Chen, Hong-lei; Hao, Lichao; Huang, Ai-Bo; Lin, Jiamu; Zhang, Jun-ling; Feng, Qi; Ding, Rui-jun
2013-01-01
Infrared focal plane HgCdTe device is used in the environment of complicated astrospace radiation. To achieve the instrument's actual service life, the anti-radiation ability is needed to study in our research. The irradiation-induced invalidation mechanism of semiconductor materials is introduced in this paper, and the screening experiments' total radiation dose of American Military Standard is also investigated in our study. Through the simulation of astrospace radiation effect by γ -irradiation, the experimental procedures are proved to be rational by the analysis of the experimental data. With the domestic conditions, radiation screening procedures which meets the practical need is suggested.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-10-23
... suspension and refund authority under section 205(e) of the FPA, to protect customers of electricity from... section 206 has eliminated some of the differences underlying the finding in Southwestern, a fundamental...
First light of Cassis: the stereo surface imaging system onboard the exomars TGO
NASA Astrophysics Data System (ADS)
Gambicorti, L.; Piazza, D.; Pommerol, A.; Roloff, V.; Gerber, M.; Ziethe, R.; El-Maarry, M. R.; Weigel, T.; Johnson, M.; Vernani, D.; Pelo, E.; Da Deppo, V.; Cremonese, G.; Ficai Veltroni, I.; Thomas, N.
2017-09-01
The Colour and Stereo Surface Imaging System (CaSSIS) camera was launched on 14 March 2016 onboard the ExoMars Trace Gas Orbiter (TGO) and it is currently in cruise to Mars. The CaSSIS high resolution optical system is based on a TMA telescope (Three Mirrors Anastigmatic configuration) with a 4th powered folding mirror compacting the CFRP (Carbon Fiber Reinforced Polymer) structure. The camera EPD (Entrance Pupil Diameter) is 135 mm and the focal length is 880 mm, giving an F# 6.5 system; the wavelength range covered by the instrument is 400-1100 nm. The optical system is designed to have distortion of less than 2%, and a worst case Modulation Transfer Function (MTF) of 0.3 at the detector Nyquist spatial frequency (i.e. 50 lp/mm). The Focal Plane Assembly (FPA), including the detector, is a spare from the Simbio-Sys instrument of the Italian Space Agency (ASI). Simbio-Sys will fly on ESA's BepiColombo mission to Mercury in 2018. The detector, developed by Raytheon Vision Systems, is a 2k×2k hybrid Si-PIN array with 10 μm-pixel pitch. The detector allows snap shot operation at a read-out rate of 5 Mpx/s with 14-bit resolution. CaSSIS will operate in a push-frame mode with a Filter Strip Assembly (FSA), placed directly above the detector sensitive area, selecting 4 colour bands. The scale at a slant angle of 4.6 m/px from the nominal orbit is foreseen to produce frames of 9.4 km × 6.3 km on the Martian surface, and covering a Field of View (FoV) of 1.33° cross track × 0.88° along track. The University of Bern was in charge of the full instrument integration as well as the characterisation of the focal plane of CaSSIS. The paper will present an overview of CaSSIS and the optical performance of the telescope and the FPA. The preliminary results of the on-ground calibration campaign and the first light obtained during the commissioning and pointing campaign (April 2016) will be described in detail. The instrument is acquiring images with an average Point Spread Function at Full-Width-Half-Maximum (PSF FWHM) of < 1.5 px, as expected.
Experiments with osteoblasts cultured under hypergravity conditions
NASA Technical Reports Server (NTRS)
Kacena, Melissa A.; Todd, Paul; Gerstenfeld, Louis C.; Landis, William J.
2004-01-01
To understand further the role of gravity in osteoblast attachment, osteoblasts were subjected to hypergravity conditions in vitro. Scanning electron microscopy of all confluent coverslips from FPA units show that the number of attached osteoblasts was similar among gravitational levels and growth durations (90 cells/microscopic field). Specifically, confluent 1.0 G control cultures contained an average of 91 +/- 8 cells/field, 3.3 G samples had 88 +/- 8 cells/field, and 4.0 G cultures averaged 90 +/- 7 cells/field. The sparsely plated cultures assessed by immunohistochemistry also had similar numbers of cells at each time point (l.0 G was similar to 3.3 and 4.0 G), but cell number changed from one time point to the next as those cells proliferated. Immunohistochemistry of centrifuged samples showed an increase in number (up to 160% increase) and thickness (up to 49% increase) of actin fibers, a decrease in intensity of fibronectin fluorescence (18-23% decrease) and an increase in number of vinculin bulbs (202-374% increase in number of vinculin bulbs/area). While hypergravity exposure did not alter the number of attached osteoblasts, it did result in altered actin, fibronectin, and vinculin elements, changing some aspects of osteoblast- substrate adhesion.
50 CFR 221.2 - What terms are used in this part?
Code of Federal Regulations, 2014 CFR
2014-10-01
... Energy Regulatory Commission. FPA means the Federal Power Act, 16 U.S.C. 791 et seq. Intervention means a... hydroelectric facility under 18 CFR parts 4 or 5. Material fact means a fact that, if proved, may affect a...
50 CFR 221.2 - What terms are used in this part?
Code of Federal Regulations, 2013 CFR
2013-10-01
... Energy Regulatory Commission. FPA means the Federal Power Act, 16 U.S.C. 791 et seq. Intervention means a... hydroelectric facility under 18 CFR parts 4 or 5. Material fact means a fact that, if proved, may affect a...
Hess, Katharina; Ajjan, Ramzi; Phoenix, Fladia; Dobó, József; Gál, Péter; Schroeder, Verena
2012-01-01
Background Numerous interactions between the coagulation and complement systems have been shown. Recently, links between coagulation and mannan-binding lectin-associated serine protease-1 (MASP-1) of the complement lectin pathway have been proposed. Our aim was to investigate MASP-1 activation of factor XIII (FXIII), fibrinogen, prothrombin, and thrombin-activatable fibrinolysis inhibitor (TAFI) in plasma-based systems, and to analyse effects of MASP-1 on plasma clot formation, structure and lysis. Methodology/Principal Findings We used a FXIII incorporation assay and specific assays to measure the activation products prothrombin fragment F1+2, fibrinopeptide A (FPA), and activated TAFI (TAFIa). Clot formation and lysis were assessed by turbidimetric assay. Clot structure was studied by scanning electron microscopy. MASP-1 activated FXIII and, contrary to thrombin, induced FXIII activity faster in the Val34 than the Leu34 variant. MASP-1-dependent generation of F1+2, FPA and TAFIa showed a dose-dependent response in normal citrated plasma (NCP), albeit MASP-1 was much less efficient than FXa or thrombin. MASP-1 activation of prothrombin and TAFI cleavage were confirmed in purified systems. No FPA generation was observed in prothrombin-depleted plasma. MASP-1 induced clot formation in NCP, affected clot structure, and prolonged clot lysis. Conclusions/Significance We show that MASP-1 interacts with plasma clot formation on different levels and influences fibrin structure. Although MASP-1-induced fibrin formation is thrombin-dependent, MASP-1 directly activates prothrombin, FXIII and TAFI. We suggest that MASP-1, in concerted action with other complement and coagulation proteins, may play a role in fibrin clot formation. PMID:22536427
78 FR 60271 - Project No. 13599-001
Federal Register 2010, 2011, 2012, 2013, 2014
2013-10-01
... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Project No. 13599-001] Green Power... (FPA), proposing to study the feasibility of the Lake 3160 Hydroelectric Project (project) to be.... The project would occupy about 475 acres of lands within the Tongass National Forest managed by the U...
NASA Astrophysics Data System (ADS)
Xu, Zhipeng; Wei, Jun; Li, Jianwei; Zhou, Qianting
2010-11-01
An image spectrometer of a spatial remote sensing satellite requires shortwave band range from 2.1μm to 3μm which is one of the most important bands in remote sensing. We designed an infrared sub-system of the image spectrometer using a homemade 640x1 InGaAs shortwave infrared sensor working on FPA system which requires high uniformity and low level of dark current. The working temperature should be -15+/-0.2 Degree Celsius. This paper studies the model of noise for focal plane array (FPA) system, investigated the relationship with temperature and dark current noise, and adopts Incremental PID algorithm to generate PWM wave in order to control the temperature of the sensor. There are four modules compose of the FPGA module design. All of the modules are coded by VHDL and implemented in FPGA device APA300. Experiment shows the intelligent temperature control system succeeds in controlling the temperature of the sensor.
Cheetah: A high frame rate, high resolution SWIR image camera
NASA Astrophysics Data System (ADS)
Neys, Joel; Bentell, Jonas; O'Grady, Matt; Vermeiren, Jan; Colin, Thierry; Hooylaerts, Peter; Grietens, Bob
2008-10-01
A high resolution, high frame rate InGaAs based image sensor and associated camera has been developed. The sensor and the camera are capable of recording and delivering more than 1700 full 640x512pixel frames per second. The FPA utilizes a low lag CTIA current integrator in each pixel, enabling integration times shorter than one microsecond. On-chip logics allows for four different sub windows to be read out simultaneously at even higher rates. The spectral sensitivity of the FPA is situated in the SWIR range [0.9-1.7 μm] and can be further extended into the Visible and NIR range. The Cheetah camera has max 16 GB of on-board memory to store the acquired images and transfer the data over a Gigabit Ethernet connection to the PC. The camera is also equipped with a full CameralinkTM interface to directly stream the data to a frame grabber or dedicated image processing unit. The Cheetah camera is completely under software control.
A Low Cost Approach to the Design of Autopilot for Hypersonic Glider
NASA Astrophysics Data System (ADS)
Liang, Wang; Weihua, Zhang; Ke, Peng; Donghui, Wang
2017-12-01
This paper proposes a novel integrated guidance and control (IGC) approach to improve the autopilot design with low cost for hypersonic glider in dive and pull-up phase. The main objective is robust and adaptive tracking of flight path angle (FPA) under severe flight scenarios. Firstly, the nonlinear IGC model is developed with a second order actuator dynamics. Then the adaptive command filtered back-stepping control is implemented to deal with the large aerodynamics coefficient uncertainties, control surface uncertainties and unmatched time-varying disturbances. For the autopilot, a back-stepping sliding mode control is designed to track the control surface deflection, and a nonlinear differentiator is used to avoid direct differentiating the control input. Through a series of 6-DOF numerical simulations, it’s shown that the proposed scheme successfully cancels out the large uncertainties and disturbances in tracking different kinds of FPA trajectory. The contribution of this paper lies in the application and determination of nonlinear integrated design of guidance and control system for hypersonic glider.
Evaluating Flight Crew Operator Manual Documentation
NASA Technical Reports Server (NTRS)
Sherry, Lance; Feary, Michael
1998-01-01
Aviation and cognitive science researchers have identified situations in which the pilot s expectations for the behavior of the avionics are not matched by the actual behavior of the avionics. Researchers have attributed these "automation surprises" to the complexity of the avionics mode logic, the absence of complete training, limitations in cockpit displays, and ad-hoc conceptual models of the avionics. Complete canonical rule-based descriptions of the behavior of the autopilot provide the basis for understanding the perceived complexity of the autopilots, the differences between the pilot s and autopilot s conceptual models, and the limitations in training materials and cockpit displays. This paper compares the behavior of the autopilot Vertical Speed/Flight Path Angle (VS-FPA) mode as described in the Flight Crew Operators Manual (FCOM) and the actual behavior of the VS-FPA mode defined in the autopilot software. This example demonstrates the use of the Operational Procedure Model (OPM) as a method for using the requirements specification for the design of the software logic as information requirements for training.
Further applications for mosaic pixel FPA technology
NASA Astrophysics Data System (ADS)
Liddiard, Kevin C.
2011-06-01
In previous papers to this SPIE forum the development of novel technology for next generation PIR security sensors has been described. This technology combines the mosaic pixel FPA concept with low cost optics and purpose-designed readout electronics to provide a higher performance and affordable alternative to current PIR sensor technology, including an imaging capability. Progressive development has resulted in increased performance and transition from conventional microbolometer fabrication to manufacture on 8 or 12 inch CMOS/MEMS fabrication lines. A number of spin-off applications have been identified. In this paper two specific applications are highlighted: high performance imaging IRFPA design and forest fire detection. The former involves optional design for small pixel high performance imaging. The latter involves cheap expendable sensors which can detect approaching fire fronts and send alarms with positional data via mobile phone or satellite link. We also introduce to this SPIE forum the application of microbolometer IR sensor technology to IoT, the Internet of Things.
Performance enhancement of uncooled infrared focal plane array by integrating metamaterial absorber
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ma, Wei; Wen, Yongzheng; Yu, Xiaomei, E-mail: yuxm@pku.edu.cn
2015-03-16
This letter presents an infrared (IR) focal plane array (FPA) with metamaterial absorber (MMA) integrated to enhance its performance. A glass substrate, on which arrays of bimaterial cantilevers are fabricated as the thermal-sensitive pixels by a polyimide surface sacrificial process, is employed to allow the optical readout from the back side of the substrate. Whereas the IR wave radiates onto the FPA from the front side, which consequently avoids the energy loss caused by the silicon substrate compared with the previous works. This structure also facilitates the integration of MMA by introducing a layer of periodic square resonators atop themore » SiN{sub x} structural layer to form a metal/dielectric/metal stack with the gold mirror functioning as the ground plane. A comparative experiment was carried out on the FPAs that use MMA and ordinary SiN{sub x} as the absorbers, respectively. The performance improvement was verified by the evaluation of the absorbers as well as the imaging results of both FPAs.« less
The influence of sorbitol on the production of cellulases and xylanases in an airlift bioreactor.
Ritter, Carla Eliana Todero; Fontana, Roselei Claudete; Camassola, Marli; da Silveira, Maurício Moura; Dillon, Aldo José Pinheiro
2013-11-01
The production of cellulases and xylanases by Penicillium echinulatum in an airlift bioreactor was evaluated. In batch production, we tested media with isolated or associated cellulose and sorbitol. In fed-batch production, we tested cellulose addition at two different times, 30 h and 48 h. Higher liquid circulation velocities in the downcomer were observed in sorbitol 10 g L(-1) medium. In batch production, higher FPA (filter paper activity) and endoglucanase activities were obtained with cellulose (7.5 g L(-1)) and sorbitol (2.5 g L(-1)), 1.0 U mL(-1) (120 h) and 6.4 U m L(-1) (100 h), respectively. For xylanases, the best production condition was cellulose 10 g L(-1), which achieved 5.5 U mL(-1) in 64 h. The fed-batch process was favorable for obtaining xylanases, but not for FPA and endoglucanases, suggesting that in the case of cellulases, the inducer must be added early in the process. Copyright © 2013 Elsevier Ltd. All rights reserved.
Wafer-level radiometric performance testing of uncooled microbolometer arrays
NASA Astrophysics Data System (ADS)
Dufour, Denis G.; Topart, Patrice; Tremblay, Bruno; Julien, Christian; Martin, Louis; Vachon, Carl
2014-03-01
A turn-key semi-automated test system was constructed to perform on-wafer testing of microbolometer arrays. The system allows for testing of several performance characteristics of ROIC-fabricated microbolometer arrays including NETD, SiTF, ROIC functionality, noise and matrix operability, both before and after microbolometer fabrication. The system accepts wafers up to 8 inches in diameter and performs automated wafer die mapping using a microscope camera. Once wafer mapping is completed, a custom-designed quick insertion 8-12 μm AR-coated Germanium viewport is placed and the chamber is pumped down to below 10-5 Torr, allowing for the evaluation of package-level focal plane array (FPA) performance. The probe card is electrically connected to an INO IRXCAM camera core, a versatile system that can be adapted to many types of ROICs using custom-built interface printed circuit boards (PCBs). We currently have the capability for testing 384x288, 35 μm pixel size and 160x120, 52 μm pixel size FPAs. For accurate NETD measurements, the system is designed to provide an F/1 view of two rail-mounted blackbodies seen through the Germanium window by the die under test. A master control computer automates the alignment of the probe card to the dies, the positioning of the blackbodies, FPA image frame acquisition using IRXCAM, as well as data analysis and storage. Radiometric measurement precision has been validated by packaging dies measured by the automated probing system and re-measuring the SiTF and Noise using INO's pre-existing benchtop system.
77 FR 2963 - Commission Information Collection Activities (FERC-725F); Comment Request
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76 FR 67158 - Commission Information Collection Activities (FERC-725F); Comment Request; Extension
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2011-10-31
..., ``Mandatory Reliability Standard for Nuclear Plant Interface Coordination'' (OMB Control No. 1902-0249), is... 215 to the FPA, which required a Commission-certified Electric Reliability Organization (ERO) to develop mandatory and enforceable Reliability Standards, which are subject to Commission review and...
Hsieh, Hong-Jung; Hu, Chih-Chung; Lu, Tung-Wu; Lu, Hsuan-Lun; Kuo, Mei-Ying; Kuo, Chien-Chung; Hsu, Horng-Chaung
2016-06-07
Robot-based joint-testing systems (RJTS) can be used to perform unconstrained laxity tests, measuring the stiffness of a degree of freedom (DOF) of the joint at a fixed flexion angle while allowing the other DOFs unconstrained movement. Previous studies using the force-position hybrid (FPH) control method proposed by Fujie et al. (J Biomech Eng 115(3):211-7, 1993) focused on anterior/posterior tests. Its convergence and applicability on other clinically relevant DOFs such as valgus/varus have not been demonstrated. The current s1tudy aimed to develop a 6-DOF RJTS using an industrial robot, to propose two new force-position hybrid control methods, and to evaluate the performance of the methods and FPH in controlling the RJTS for anterior/posterior and valgus/varus laxity tests of the knee joint. An RJTS was developed using an industrial 6-DOF robot with a 6-component load-cell attached at the effector. The performances of FPH and two new control methods, namely force-position alternate control (FPA) and force-position hybrid control with force-moment control (FPHFM), for unconstrained anterior/posterior and valgus/varus laxity tests were evaluated and compared with traditional constrained tests (CT) in terms of the number of control iterations, total time and the constraining forces and moments. As opposed to CT, the other three control methods successfully reduced the constraining forces and moments for both anterior/posterior and valgus/varus tests, FPHFM being the best followed in order by FPA and FPH. FPHFM had root-mean-squared constraining forces and moments of less than 2.2 N and 0.09 Nm, respectively at 0° flexion, and 2.3 N and 0.14 Nm at 30° flexion. The corresponding values for FPH were 8.5 N and 0.33 Nm, and 11.5 N and 0.45 Nm, respectively. Given the same control parameters including the compliance matrix, FPHFM and FPA reduced the constraining loads of FPH at the expense of additional control iterations, and thus increased total time, FPA taking about 10 % longer than FPHFM. The FPHFM would be the best choice among the methods considered when longer total time is acceptable in the intended clinical applications. The current results will be useful for selecting a force-position hybrid control method for unconstrained laxity tests using an RJTS.
Status of backthinned AlGaN based focal plane arrays for deep-UV imaging
NASA Astrophysics Data System (ADS)
Reverchon, J.-L.; Lehoucq, G.; Truffer, J.-P.; Costard, E.; Frayssinet, E.; Semond, F.; Duboz, J.-Y.; Giuliani, A.; Réfrégiers, M.; Idir, M.
2017-11-01
The achievement of deep ultraviolet (UV) focal plane arrays (FPA) is required for both solar physics [1] and micro electronics industry. The success of solar mission (SOHO, STEREO [2], SDO [3]…), has shown the accuracy of imaging at wavelengths from 10 nm to 140 nm to reveal effects occurring in the sun corona. Deep UV steppers at 13 nm are another demanding imaging technology for the microelectronic industry in terms of uniformity and stability. A third application concerns beam shaping of Synchrotron lines [4]. Consequently, such wavelengths are of prime importance whereas the vacuum UV wavelengths are very difficult to detect due to the dramatic interaction of light with materials. The fast development of nitrides has given the opportunity to investigate AlGaN as a material for UV detection. Camera based on AlGaN present an intrinsic spectral selectivity and an extremely low dark current at room temperature. We have previously presented several FPA dedicated to deep UV based on 320 x 256 pixels of Schottky photodiodes with a pitch of 30 μm [4, 5]. AlGaN is grown on a silicon substrate instead of sapphire substrate only transparent down to 200 nm. After a flip-chip hybridization, silicon substrate and AlGaN basal layer was removed by dry etching. Then, the spectral responsivity of the FPA presented a quantum efficiency (QE) from 5% to 20% from 50 nm to 290 nm when removing the highly doped contact layer via a selective wet etching. This FPA suffered from a low uniformity incompatible with imaging, and a long time response due to variations of conductivity in the honeycomb. We also observed a low rejection of visible. It is probably due to the same honeycomb conductivity enhancement for wavelength shorter than 360 nm, i.e., the band gap of GaN. We will show hereafter an improved uniformity due to the use of a precisely ICP (Inductively Coupled Plasma) controlled process. The final membrane thickness is limited to the desertion layer. Neither access resistance limitation nor long response time are observed. QE varies from 5% at 50 nm to 15% at 6 nm (85% more when taking into account the filling factor). Consequently, we can propose prototypes concerning not only "solar blind" camera optimized for narrow band in the near UV range (between 280 nm and 260 nm), but also devices with spectral range extended in the deep UV (290 nm to 10 nm). Both detectors are available for an optical budget evaluation.
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50 CFR 221.2 - What terms are used in this part?
Code of Federal Regulations, 2010 CFR
2010-10-01
... Section 221.2 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS PRESCRIPTIONS IN FERC HYDROPOWER LICENSES General... Energy Regulatory Commission. FPA means the Federal Power Act, 16 U.S.C. 791 et seq. Intervention means a...
76 FR 49469 - Orlando Utilities Commission; Notice of Filing
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NASA Astrophysics Data System (ADS)
Haran, Terence L.; James, J. Christopher; Cincotta, Tomas E.
2017-08-01
The majority of high performance infrared systems today utilize FPAs composed of intrinsic direct bandgap semiconductor photon detectors such as MCT or InSb. Quantum well detector technologies such as QWIPs, QDIPs, and SLS photodetectors are potentially lower cost alternatives to MCT and InSb, but the relative performance of these technologies has not been sufficiently high to allow widespread adoption outside of a handful of applications. While detectors are often evaluated using figures of merit such as NETD or D∗, these metrics, which include many underlying aspects such as spectral quantum efficiency, dark current, well size, MTF, and array response uniformity, may be far removed from the performance metrics used to judge performance of a system in an operationally relevant scenario. True comparisons of performance for various detector technologies from the perspective of end-to-end system performance have rarely been conducted, especially considering the rapid progress of the newer quantum well technologies. System level models such as the US Army's Night Vision Integrated Performance Model (NV-IPM) can calculate image contrast and spatial frequency content using data from the target/background, intervening atmosphere, and system components. This paper includes results from a performance parameter sensitivity analysis using NV-IPM to determine the relative importance of various FPA performance parameters to the overall performance of a long range imaging system. Parameters included are: QE, dark current density, quantum well capacity, downstream readout noise, well fill, image frame rate, frame averaging, and residual fixed pattern noise. The state-of-the art for XBn, QWIP, and SLS detector technologies operating in the MWIR and LWIR bands will be surveyed to assess performance of quantum structures compared to MCT and InSb. The intent is to provide a comprehensive assessment of quantum detector performance and to identify areas where increased research could provide the most benefit to overall system level performance.
Characterization of mannitol in Curvularia protuberata hyphae by FTIR and Raman spectromicroscopy.
Isenor, Merrill; Kaminskyj, Susan G W; Rodriguez, Russell J; Redman, Regina S; Gough, Kathleen M
2010-12-01
FTIR and Raman spectromicroscopy were used to characterize the composition of Curvularia protuberata hyphae, and to compare a strain isolated from plants inhabiting geothermal soils with a non-geothermal isolate. Thermal IR source images of hyphae have been acquired with a 64 × 64 element focal plane array detector; single point IR spectra have been obtained with synchrotron source light. In some C. protuberata hyphae, we have discovered the spectral signature of crystalline mannitol, a fungal polyol with complex protective roles. With FTIR-FPA imaging, we have determined that the protein content in cells remains fairly constant throughout the length of a hypha, whereas the mannitol is found at discrete, irregular locations. This is the first direct observation of mannitol in intact fungal hyphae. Since the concentration of mannitol in cells varies with respect to position and is not present in all hyphae, this discovery may be related to habitat adaptation, fungal structure and growth stages.
Design and simulation of the circuit of SWIR hyper-spectral imaging spectrometer
NASA Astrophysics Data System (ADS)
Ren, Bin; Li, Zi-tian; Meng, Nan
2009-07-01
With the requirement of the SWIR Hyper-spectral Imaging Spectrometer, this article describes a project of SWIR image circuit based on IRFPA detector. First, the structure of the SWIR Hyper-spectral Imaging Spectrometer is introduced in this paper, and then the infrared imaging circuit design is proposed, which is based on MCT SWIR FPA with 500*256 pixels, the detector NEPTURN, in Safradir Company. According to the scheme, several key technologies have been studied in particular, such as driving circuit, time control circuit, high-speed A/D converter, LVDS (Low Voltage Differential Signaling) transmission circuit. At last, An improved two-point Correction Method was chosen to correct the Non-uniformity of image. The simulation results demonstrate that the proposed method can effectively suppress noises and work with low power consumption. The electric system not only has the advantages of simplicity and compactness but also can work stably, providing 500×256 image at the frame frequency of 200 Hz in good quality.
Characterization of mannitol in Curvularia protuberata hyphae by FTIR and Raman spectromicroscopy
Isenor, M.; Kaminskyj, S.G.W.; Rodriguez, R.J.; Redman, R.S.; Gough, K.M.
2010-01-01
FTIR and Raman spectromicroscopy were used to characterize the composition of Curvularia protuberata hyphae, and to compare a strain isolated from plants inhabiting geothermal soils with a non-geothermal isolate. Thermal IR source images of hyphae have been acquired with a 64 ?? 64 element focal plane array detector; single point IR spectra have been obtained with synchrotron source light. In some C. protuberata hyphae, we have discovered the spectral signature of crystalline mannitol, a fungal polyol with complex protective roles. With FTIR-FPA imaging, we have determined that the protein content in cells remains fairly constant throughout the length of a hypha, whereas the mannitol is found at discrete, irregular locations. This is the first direct observation of mannitol in intact fungal hyphae. Since the concentration of mannitol in cells varies with respect to position and is not present in all hyphae, this discovery may be related to habitat adaptation, fungal structure and growth stages. ?? 2010 The Royal Society of Chemistry.
Characterization of mannitol in Curvularia protuberata hyphae by FTIR and Raman spectromicroscopy
Rodriguez, Russell J.; Isenor, Merrill; Kaminsky, Susan G.W.; Redman, S.; Gough, Kathleen M.
2010-01-01
FTIR and Raman spectromicroscopy were used to characterize the composition of Curvularia protuberata hyphae, and to compare a strain isolated from plants inhabiting geothermal soils with a non-geothermal isolate. Thermal IR source images of hyphae have been acquired with a 64 × 64 element focal plane array detector; single point IR spectra have been obtained with synchrotron source light. In some C. protuberata hyphae, we have discovered the spectral signature of crystalline mannitol, a fungal polyol with complex protective roles. With FTIR-FPA imaging, we have determined that the protein content in cells remains fairly constant throughout the length of a hypha, whereas the mannitol is found at discrete, irregular locations. This is the first direct observation of mannitol in intact fungal hyphae. Since the concentration of mannitol in cells varies with respect to position and is not present in all hyphae, this discovery may be related to habitat adaptation, fungal structure and growth stages.
Capability of long distance 100 GHz FMCW using a single GDD lamp sensor.
Levanon, Assaf; Rozban, Daniel; Aharon Akram, Avihai; Kopeika, Natan S; Yitzhaky, Yitzhak; Abramovich, Amir
2014-12-20
Millimeter wave (MMW)-based imaging systems are required for applications in medicine, homeland security, concealed weapon detection, and space technology. The lack of inexpensive room temperature imaging sensors makes it difficult to provide a suitable MMW system for many of the above applications. A 3D MMW imaging system based on chirp radar was studied previously using a scanning imaging system of a single detector. The radar system requires that the millimeter wave detector will be able to operate as a heterodyne detector. Since the source of radiation is a frequency modulated continuous wave (FMCW), the detected signal as a result of heterodyne detection gives the object's depth information according to value of difference frequency, in addition to the reflectance of the 2D image. New experiments show the capability of long distance FMCW detection by using a large scale Cassegrain projection system, described first (to our knowledge) in this paper. The system presents the capability to employ a long distance of at least 20 m with a low-cost plasma-based glow discharge detector (GDD) focal plane array (FPA). Each point on the object corresponds to a point in the image and includes the distance information. This will enable relatively inexpensive 3D MMW imaging.
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43 CFR 45.2 - What terms are used in this part?
Code of Federal Regulations, 2012 CFR
2012-10-01
... Department of the Interior, including any bureau, unit, or office of the Department, whether in Washington... Federal Energy Regulatory Commission. FPA means the Federal Power Act, 16 U.S.C. 791 et seq. Hearings... impact statement issued to comply with the requirements of the National Environmental Policy Act of 1969...
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Code of Federal Regulations, 2014 CFR
2014-10-01
... Department of the Interior, including any bureau, unit, or office of the Department, whether in Washington... Federal Energy Regulatory Commission. FPA means the Federal Power Act, 16 U.S.C. 791 et seq. Hearings... impact statement issued to comply with the requirements of the National Environmental Policy Act of 1969...
43 CFR 45.2 - What terms are used in this part?
Code of Federal Regulations, 2011 CFR
2011-10-01
... Department of the Interior, including any bureau, unit, or office of the Department, whether in Washington... Federal Energy Regulatory Commission. FPA means the Federal Power Act, 16 U.S.C. 791 et seq. Hearings... impact statement issued to comply with the requirements of the National Environmental Policy Act of 1969...
43 CFR 45.2 - What terms are used in this part?
Code of Federal Regulations, 2010 CFR
2010-10-01
... Department of the Interior, including any bureau, unit, or office of the Department, whether in Washington... Federal Energy Regulatory Commission. FPA means the Federal Power Act, 16 U.S.C. 791 et seq. Hearings... impact statement issued to comply with the requirements of the National Environmental Policy Act of 1969...
43 CFR 45.2 - What terms are used in this part?
Code of Federal Regulations, 2013 CFR
2013-10-01
... Department of the Interior, including any bureau, unit, or office of the Department, whether in Washington... Federal Energy Regulatory Commission. FPA means the Federal Power Act, 16 U.S.C. 791 et seq. Hearings... impact statement issued to comply with the requirements of the National Environmental Policy Act of 1969...
78 FR 34361 - Combined Notice of Filings #2
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2013-06-07
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78 FR 65639 - Notice of Filing; Wyrsch, Martha B.
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75 FR 28001 - Ken Willis; Notice of Authorization for Continued Project Operation
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2010-05-19
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USDA-ARS?s Scientific Manuscript database
The chemical imaging of cotton fibers and common contaminants in fibers is presented. Chemical imaging was performed with an infrared microscope equipped with a Focal-Plane Array (FPA) detector. Infrared spectroscopy can provide us with information on the structure and quality of cotton fibers. In a...
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NASA Technical Reports Server (NTRS)
Gunapala, S.; Bandara, S. V.; Liu, J. K.; Hong, W.; Sundaram, M.; Maker, P. D.; Muller, R. E.
1997-01-01
In this paper, we discuss the development of this very sensitive long waelength infrared (LWIR) camera based on a GaAs/AlGaAs QWIP focal plane array (FPA) and its performance in quantum efficiency, NEAT, uniformity, and operability.
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Demonstration of 1024x1024 pixel dual-band QWIP focal plane array
NASA Astrophysics Data System (ADS)
Gunapala, S. D.; Bandara, S. V.; Liu, J. K.; Mumolo, J. M.; Ting, D. Z.; Hill, C. J.; Nguyen, J.; Rafol, S. B.
2010-04-01
QWIPs are well known for their stability, high pixel-pixel uniformity and high pixel operability which are quintessential parameters for large area imaging arrays. In this paper we report the first demonstration of the megapixel-simultaneously-readable and pixel-co-registered dual-band QWIP focal plane array (FPA). The dual-band QWIP device was developed by stacking two multi-quantum-well stacks tuned to absorb two different infrared wavelengths. The full width at half maximum (FWHM) of the mid-wave infrared (MWIR) band extends from 4.4 - 5.1 μm and FWHM of the long-wave infrared (LWIR) band extends from 7.8 - 8.8 μm. Dual-band QWIP detector arrays were hybridized with direct injection 30 μm pixel pitch megapixel dual-band simultaneously readable CMOS read out integrated circuits using the indium bump hybridization technique. The initial dual-band megapixel QWIP FPAs were cooled to 68K operating temperature. The preliminary data taken from the first megapixel QWIP FPA has shown system NE▵T of 27 and 40 mK for MWIR and LWIR bands respectively.
NASA Astrophysics Data System (ADS)
Gutschwager, Berndt; Hollandt, Jörg
2017-01-01
We present a novel method of nonuniformity correction (NUC) of infrared cameras and focal plane arrays (FPA) in a wide optical spectral range by reading radiance temperatures and by applying a radiation source with an unknown and spatially nonhomogeneous radiance temperature distribution. The benefit of this novel method is that it works with the display and the calculation of radiance temperatures, it can be applied to radiation sources of arbitrary spatial radiance temperature distribution, and it only requires sufficient temporal stability of this distribution during the measurement process. In contrast to this method, an initially presented method described the calculation of NUC correction with the reading of monitored radiance values. Both methods are based on the recording of several (at least three) images of a radiation source and a purposeful row- and line-shift of these sequent images in relation to the first primary image. The mathematical procedure is explained in detail. Its numerical verification with a source of a predefined nonhomogeneous radiance temperature distribution and a thermal imager of a predefined nonuniform FPA responsivity is presented.
Super-resolution for imagery from integrated microgrid polarimeters.
Hardie, Russell C; LeMaster, Daniel A; Ratliff, Bradley M
2011-07-04
Imagery from microgrid polarimeters is obtained by using a mosaic of pixel-wise micropolarizers on a focal plane array (FPA). Each distinct polarization image is obtained by subsampling the full FPA image. Thus, the effective pixel pitch for each polarization channel is increased and the sampling frequency is decreased. As a result, aliasing artifacts from such undersampling can corrupt the true polarization content of the scene. Here we present the first multi-channel multi-frame super-resolution (SR) algorithms designed specifically for the problem of image restoration in microgrid polarization imagers. These SR algorithms can be used to address aliasing and other degradations, without sacrificing field of view or compromising optical resolution with an anti-aliasing filter. The new SR methods are designed to exploit correlation between the polarimetric channels. One of the new SR algorithms uses a form of regularized least squares and has an iterative solution. The other is based on the faster adaptive Wiener filter SR method. We demonstrate that the new multi-channel SR algorithms are capable of providing significant enhancement of polarimetric imagery and that they outperform their independent channel counterparts.
NASA Astrophysics Data System (ADS)
Zhang, Wenyu; Yang, Yushu; Zhang, Shuai; Yu, Dejian; Chen, Yong
2018-05-01
With the growing complexity of customer requirements and the increasing scale of manufacturing services, how to select and combine the single services to meet the complex demand of the customer has become a growing concern. This paper presents a new manufacturing service composition method to solve the multi-objective optimization problem based on quality of service (QoS). The proposed model not only presents different methods for calculating the transportation time and transportation cost under various structures but also solves the three-dimensional composition optimization problem, including service aggregation, service selection, and service scheduling simultaneously. Further, an improved Flower Pollination Algorithm (IFPA) is proposed to solve the three-dimensional composition optimization problem using a matrix-based representation scheme. The mutation operator and crossover operator of the Differential Evolution (DE) algorithm are also used to extend the basic Flower Pollination Algorithm (FPA) to improve its performance. Compared to Genetic Algorithm, DE, and basic FPA, the experimental results confirm that the proposed method demonstrates superior performance than other meta heuristic algorithms and can obtain better manufacturing service composition solutions.
Radiometric packaging of uncooled bolometric infrared focal plane arrays
NASA Astrophysics Data System (ADS)
García-Blanco, Sonia; Pope, Timothy; Côté, Patrice; Leclerc, Mélanie; Ngo Phong, Linh; Châteauneuf, François
2017-11-01
INO has a wide experience in the design and fabrication of different kinds of microbolometer focal plane arrays (FPAs). In particular, a 512x3 pixel microbolometer FPA has been selected as the sensor for the New Infrared Sensor Technology (NIRST) instrument, one of the payloads of the SACD/Aquarius mission. In order to make the absolute temperature measurements necessary for many infrared Earth observation applications, the microbolometer FPA must be integrated into a package offering a very stable thermal environment. The radiometric packaging technology developed at INO presents an innovative approach since it was conceived to be modular and adaptable for the packaging of different microbolometer FPAs and for different sets of assembly requirements without need for requalification of the assembly process. The development of the radiometric packaging technology has broadened the position of INO as a supplier of radiometric detector modules integrating FPAs of microbolometers inside a radiometric package capable of achieving the requirements of different space missions. This paper gives an overview of the design of INO's radiometric package. Key performance parameters are also discussed and the test campaign conducted with the radiometric package is presented.
Stereo Imaging Miniature Endoscope with Single Imaging Chip and Conjugated Multi-Bandpass Filters
NASA Technical Reports Server (NTRS)
Shahinian, Hrayr Karnig (Inventor); Bae, Youngsam (Inventor); White, Victor E. (Inventor); Shcheglov, Kirill V. (Inventor); Manohara, Harish M. (Inventor); Kowalczyk, Robert S. (Inventor)
2018-01-01
A dual objective endoscope for insertion into a cavity of a body for providing a stereoscopic image of a region of interest inside of the body including an imaging device at the distal end for obtaining optical images of the region of interest (ROI), and processing the optical images for forming video signals for wired and/or wireless transmission and display of 3D images on a rendering device. The imaging device includes a focal plane detector array (FPA) for obtaining the optical images of the ROI, and processing circuits behind the FPA. The processing circuits convert the optical images into the video signals. The imaging device includes right and left pupil for receiving a right and left images through a right and left conjugated multi-band pass filters. Illuminators illuminate the ROI through a multi-band pass filter having three right and three left pass bands that are matched to the right and left conjugated multi-band pass filters. A full color image is collected after three or six sequential illuminations with the red, green and blue lights.
NeuroSeek dual-color image processing infrared focal plane array
NASA Astrophysics Data System (ADS)
McCarley, Paul L.; Massie, Mark A.; Baxter, Christopher R.; Huynh, Buu L.
1998-09-01
Several technologies have been developed in recent years to advance the state of the art of IR sensor systems including dual color affordable focal planes, on-focal plane array biologically inspired image and signal processing techniques and spectral sensing techniques. Pacific Advanced Technology (PAT) and the Air Force Research Lab Munitions Directorate have developed a system which incorporates the best of these capabilities into a single device. The 'NeuroSeek' device integrates these technologies into an IR focal plane array (FPA) which combines multicolor Midwave IR/Longwave IR radiometric response with on-focal plane 'smart' neuromorphic analog image processing. The readout and processing integrated circuit very large scale integration chip which was developed under this effort will be hybridized to a dual color detector array to produce the NeuroSeek FPA, which will have the capability to fuse multiple pixel-based sensor inputs directly on the focal plane. Great advantages are afforded by application of massively parallel processing algorithms to image data in the analog domain; the high speed and low power consumption of this device mimic operations performed in the human retina.
Han, Xiaolong; Song, Wenxia; Liu, Guodong; Li, Zhonghai; Yang, Piao; Qu, Yinbo
2017-03-01
Medium optimization and repeated fed-batch fermentation were performed to improve the cellulase productivity by P. oxalicum RE-10 in submerged fermentation. First, Plackett-Burman design (PBD) and central composite design (CCD) were used to optimize the medium for cellulase production. PBD demonstrated wheat bran and NaNO 3 had significant influences on cellulase production. The CCD results showed the maximum filter paper activity (FPA) production of 8.61U/mL could be achieved in Erlenmeyer flasks. The maximal FPA reached 12.69U/mL by submerged batch fermentation in a 7.5-L stirred tank, 1.76-fold higher than that on the original medium. Then, the repeated fed-batch fermentation strategy was performed successfully for increasing the cellulase productivity from 105.75U/L/h in batch fermentation to 158.38U/L/h. The cellulase activity and the glucan conversion of delignined corn cob residue hydrolysis had no significant difference between the enzymes sampled from different cycles of the repeated fed-batch fermentation and that from batch culture. Copyright © 2016 Elsevier Ltd. All rights reserved.
The Future of Single- to Multi-band Detector Technologies: Review
NASA Technical Reports Server (NTRS)
Abedin, M. Nurul; Bhat, Ishwara; Gunapala, Sarath D.; Bandara, Sumith V.; Refaat, Tamer F.; Sandford, Stephen P.; Singh, Upendra N.
2006-01-01
Using classical optical components such as filters, prisms and gratings to separate the desired wavelengths before they reach the detectors results in complex optical systems composed of heavy components. A simpler system will result by utilizing a single optical system and a detector that responds separately to each wavelength band. Therefore, a continuous endeavors to develop the capability to reliably fabricate detector arrays that respond to multiple wavelength regions. In this article, we will review the state-of-the-art single and multicolor detector technologies over a wide spectral-range, for use in space-based and airborne remote sensing applications. Discussions will be focused on current and the most recently developed focal plane arrays (FPA) in addition to emphasizing future development in UV-to-Far infrared multicolor FPA detectors for next generation space-based instruments to measure water vapor and greenhouse gases. This novel detector component will make instruments designed for these critical measurements more efficient while reducing complexity and associated electronics and weight. Finally, we will discuss the ongoing multicolor detector technology efforts at NASA Langley Research Center, Jet Propulsion Laboratory, Rensselaer Polytechnic Institute, and others.
Trifiletti, A; Bartolone, S; Scamardi, R; Pizzoleo, M A; Attinà, A; Sottilotta, G; Canobbio, V; Soraci, S; Barbera, N
1999-03-01
In this study the action of a prostaglandin, PGE1, was studied in a group of patients with peripheral arterial occlusive disease (PAOD). In 16 patients (14 men and 2 women, aged 47-70 years, mean 57 +/- 7) with PAOD, Fontaine stage IIb and III in critical ischemia, the effects on two indexes of thrombin generation and action of the endovenous administration (2 hours) of 60 micrograms of Alprostadil-PGE1 for four weeks were evaluated. In all artheriopathic patients, before and after pharmacological treatment, the following haemostatic parameters were evaluated: the prothrombin fragment 1 + 2 (F1 + 2) and the fibrinopeptide A(FPA). The patients showed plasma levels of FPA significantly decreased at the end of the treatment. On the other hand, no significant difference in plasma F1 + 2 levels was observed after treatment. These results seem to indicate that plasma F1 + 2 levels are significantly elevated, as a marker of thrombosis status, in patients with PAOD before and after treatment with PGE1.
NASA Technical Reports Server (NTRS)
Markham, Brian L.; Jenstrom, Del; Masek, Jeffrey G.; Dabney, Phil; Pedelty, Jeffrey A.; Barsi, Julia A.; Montanaro, Matthew
2016-01-01
The Landsat 9 mission, currently under development and proceeding towards a targeted launch in late 2020, will be very similar to the Landsat 8 mission, launched in 2013. Like Landsat 8, Landsat 9 is a joint effort between NASA and USGS with two sensors, the Operational Land Imager 2 (OLI-2), essentially a copy of the OLI on Landsat 8 and the Thermal Infrared Sensor 2 (TIRS-2), very similar to the TIRS on Landsat 8. The OLI-2, like OLI, provides 14-bit image data, though for Landsat 9, all 14 bits will be retained and transmitted to the ground. The focal plane modules to be used for OLI-2 were flight spares for OLI and are currently being retested by Ball Aerospace. Results indicate radiometric performance comparable to OLI. The TIRS was a class C instrument, with a 3-year design lifetime, and therefore had limited redundancy. TIRS-2 will be a class B instrument, with a 5-year design lifetime, like OLI (and OLI-2), necessitating design changes to increase redundancy. The stray light and Scene Select Mechanism (SSM) encoder problems observed on orbit with TIRS have also instigated a few design changes to TIRS-2. Stray light analysis and testing have indicated that additional baffles in the TIRS-2 optical system will suppress the out-of-field response. The SSM encoder problems have not been definitively traced to a route cause, though conductive anodic filament growth in the circuit boards is suspected. Improved designs for the encoder are being considered for TIRS-2. The spare Focal Plane Array (FPA) from TIRS is planned for use in TIRS-2; FPA spectral and radiometric performance testing is scheduled for September of this year at NASA's Goddard Space Flight Center.
Characteristics of salt taste and free chlorine or chloramine in drinking water.
Wiesenthal, K E; McGuire, M J; Suffet, I H
2007-01-01
Salty taste with or without chlorine or chloramine flavour is one of the major consumer complaints to water utilities. The flavour profile analysis (FPA) taste panel method determined the average taste threshold concentration for salt (NaCl) in Milli-Q water to be 640 +/- 3 mg/L at pH 8. Chlorine and chloramine disinfectants have no antagonistic or synergistic effects on the taste of NaCl, salt, in Milli-Q water. The flavour threshold concentrations for chlorine or chloramine in Milli-Q water alone or in the presence of NaCl could not be estimated by the Weber-Fechner curves due to the chlorine or chloramine flavour outliers in the 0.2-0.8 mg/L concentration range. Apparently, NaCl is not equilibrated with the concentration of ions in the saliva in the mouth and the concentration of free chlorine or chloramines cannot be tasted correctly. Therefore, dechlorinated tap water may be the best background water to use for a particular drinking water evaluation of chlorine and chloramine thresholds. Laboratory FPA studies of free chlorine found that a 67% dilution of Central Arizona Project (CAP) (Tucson, AZ) water with Milli-O water was required to reduce the free chlorine flavour to a threshold value instead of a theoretical value of 80% (Krasner and Barrett, 1980). No synergistic effect was found for chlorine flavour on the dilution of CAP water with Milli-Q water. When Central Avra Valley (AVRA) groundwater was used for the dilution of CAP water, a synergistic effect of the TDS present was observed for the chlorine flavour. Apparently, the actual mineral content of drinking water, and not just NaCl in Milli-Q water, is needed for comparative flavour tests for chlorine and chloramines.
sCMOS detector for imaging VNIR spectrometry
NASA Astrophysics Data System (ADS)
Eckardt, Andreas; Reulke, Ralf; Schwarzer, Horst; Venus, Holger; Neumann, Christian
2013-09-01
The facility Optical Information Systems (OS) at the Robotics and Mechatronics Center of the German Aerospace Center (DLR) has more than 30 years of experience with high-resolution imaging technology. This paper shows the scientific results of the institute of leading edge instruments and focal plane designs for EnMAP VIS/NIR spectrograph. EnMAP (Environmental Mapping and Analysis Program) is one of the selected proposals for the national German Space Program. The EnMAP project includes the technological design of the hyper spectral space borne instrument and the algorithms development of the classification. The EnMAP project is a joint response of German Earth observation research institutions, value-added resellers and the German space industry like Kayser-Threde GmbH (KT) and others to the increasing demand on information about the status of our environment. The Geo Forschungs Zentrum (GFZ) Potsdam is the Principal Investigator of EnMAP. DLR OS and KT were driving the technology of new detectors and the FPA design for this project, new manufacturing accuracy and on-chip processing capability in order to keep pace with the ambitious scientific and user requirements. In combination with the engineering research, the current generations of space borne sensor systems are focusing on VIS/NIR high spectral resolution to meet the requirements on earth and planetary observation systems. The combination of large swath and high spectral resolution with intelligent synchronization control, fast-readout ADC chains and new focal-plane concepts open the door to new remote-sensing and smart deep space instruments. The paper gives an overview over the detector verification program at DLR on FPA level, new control possibilities for sCMOS detectors in global shutter mode and key parameters like PRNU, DSNU, MTF, SNR, Linearity, Spectral Response, Quantum Efficiency, Flatness and Radiation Tolerance will be discussed in detail.
Saxon, Richard R; Chervu, Arun; Jones, Paul A; Bajwa, Tanvir K; Gable, Dennis R; Soukas, Peter A; Begg, Richard J; Adams, John G; Ansel, Gary M; Schneider, Darren B; Eichler, Charles M; Rush, Michael J
2013-02-01
To evaluate the performance of a heparin-bonded, expanded polytetrafluoroethylene (ePTFE)-lined nitinol endoprosthesis in the treatment of long-segment occlusive disease of the femoropopliteal artery (FPA) and to identify factors associated with loss of patency. In a single-arm, prospective, 11-center study (VIPER [Gore Viabahn Endoprosthesis with Heparin Bioactive Surface in the Treatment of Superficial Femoral Artery Obstructive Disease] trial), 119 limbs (113 patients; 69 men; mean age, 67 y), including 88 with Rutherford category 3-5 disease and 72 with Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II) C or D lesions of the FPA, underwent stent graft implantation. The mean lesion length was 19 cm; 56% of lesions were occlusions. Follow-up evaluations included color duplex ultrasonography in all patients, with patency defined as a peak systolic velocity ratio< 2.5. At 12 months, Rutherford category and ankle-brachial index (ABI) were significantly improved (mean category improvement, 2.4; ABI increased from 0.6±0.2 to 0.9±0.19; P<.0001). Primary and secondary patency rates were 73% and 92%. The primary patency for devices oversized<20% at the proximal landing zone was 88%, whereas the primary patency for devices oversized by>20% was 70% (P = .047). Primary patency was not significantly affected by device diameter (5 vs 6 vs 7 mm) or lesion length (≤20 cm vs>20 cm). The 30-day major adverse event rate was 0.8%. The heparin-bonded, ePTFE/nitinol stent graft provided clinical improvement and a primary patency rate of 73% at 1 year in the treatment of long-segment FPA disease. Careful sizing of the device relative to vessel landing zones is essential for achieving optimal outcomes. Copyright © 2013 SIR. Published by Elsevier Inc. All rights reserved.
A 400 KHz line rate 2048-pixel stitched SWIR linear array
NASA Astrophysics Data System (ADS)
Anchlia, Ankur; Vinella, Rosa M.; Gielen, Daphne; Wouters, Kristof; Vervenne, Vincent; Hooylaerts, Peter; Deroo, Pieter; Ruythooren, Wouter; De Gaspari, Danny; Das, Jo; Merken, Patrick
2016-05-01
Xenics has developed a family of stitched SWIR long linear arrays that operate up to 400 KHz of line rate. These arrays serve medical and industrial applications that require high line rates as well as space applications that require long linear arrays. The arrays are based on a modular ROIC design concept: modules of 512 pixels are stitched during fabrication to achieve 512, 1024 and 2048 pixel arrays. Each 512-pixel module has its own on-chip digital sequencer, analog readout chain and 4 output buffers. This modular concept enables a long array to run at a high line rates irrespective of the array length, which limits the line rate in a traditional linear array. The ROIC is flip-chipped with InGaAs detector arrays. The FPA has a pixel pitch of 12.5μm and has two pixel flavors: square (12.5μm) and rectangular (250μm). The frontend circuit is based on Capacitive Trans-impedance Amplifier (CTIA) to attain stable detector bias, and good linearity and signal integrity, especially at high speeds. The CTIA has an input auto-zero mechanism that allows to have low detector bias (<20mV). An on-chip Correlated Double Sample (CDS) facilitates removal of CTIA KTC and 1/f noise, and other offsets, achieving low noise performance. There are five gain modes in the FPA giving the full well range from 85Ke- to 40Me-. The measured input referred noise is 35e-rms in the highest gain mode. The FPA operates in Integrate While Read mode and, at a master clock rate of 60MHz and a minimum integration time of 1.4μs, achieves the highest line rate of 400 KHz. In this paper, design details and measurements results are presented in order to demonstrate the array performance.
Influence of infusion volume on the ocular hemodynamic effects of peribulbar anesthesia.
Lung, Solveig; Luksch, Alexandra; Weigert, Günther; Georgopoulos, Michael; Menapace, Rupert; Polska, Elzbieta; Garhofer, Gerhard; Findl, Oliver; Schmetterer, Leopold
2006-09-01
To test the hypothesis that ocular blood-flow response to peribulbar anesthesia can be reduced by using a smaller volume of anesthetic mixture. Departments of Ophthalmology and Clinical Pharmacology, Medical University of Vienna, Vienna, Austria. Twenty patients scheduled for bilateral age-related cataract surgery were enrolled in a prospective randomized balanced observer-masked crossover study. Two study days with a 2 mL injection volume or 5 mL injection volume used for peribulbar anesthesia were scheduled. On 1 study day, patients received the 1-dose regimen and on the other study day, when the contralateral eye had surgery, patients received the other injection volume. On both study days, the anesthetic mixture consisted of an equal amount of lidocaine, bupivacaine, and hyaluronidase independently of the injection volume. Intraocular pressure (IOP), blood pressure, and pulse rate were measured noninvasively. Ocular fundus pulsation amplitude (FPA) and peak systolic and end diastolic flow velocities in the central retinal artery were measured with laser interferometry and color Doppler imaging, respectively. The results were recorded as means +/- SD. Peribulbar anesthesia increased IOP and reduced FPA and flow velocities in the central retinal artery. The effects on IOP (5 mL, 35.1% +/- 16.0%; 2 mL, 14.1% +/- 14.1%; P<.001) and ocular hemodynamic parameters (FPA: 5 mL, -17.5% +/- 7.8%/2 mL, -7.3% +/- 7.2%, P<.001; peak systolic velocity: 5 mL, -19.5% +/- 10.7%/2 mL, -10.6% +/- 9.8%, P = .013; end diastolic velocity: 5 mL, -16.7% +/- 6.2%/2 mL, -8.4% +/- 7.3%, P = .005) were more pronounced with the 5 mL injection volume than with the 2 mL injection volume. An injection volume of 2 mL instead of 5 mL reduced the ocular blood-flow response to peribulbar anesthesia. This procedure may be used in patients with ocular vascular disease to reduce the incidence of anesthesia-induced ischemia and loss of vision.
Test equipment data package for the KC-135 fiber pulling apparatus
NASA Technical Reports Server (NTRS)
Kosten, Sue; Smith, Guy A.; Workman, Gary; Tucker, Dennis
1991-01-01
The Fiber Pulling Apparatus (FPA) is a device designed to produce continuous glass fibers from simulated lunar soil, and to determine the effects of reduced gravity, specifically 1/6 g on fiber formation and resultant properties. Briefly, pre-melt simulated lunar soil will be placed in a pint crucible and heated to 1200 C or higher, up to a maximum temperature of 1400 C. At a given temperature, a quartz fiber will be immersed into the melt and then pulled through a chill block and wound onto a cylindrical bobbin using a servo motor control. A high resolution video camera will record the fiber as it is being pulled. This assembly wil be enclosed in Plexiglas. Before fiber pulling commences, the apparatus will be backfilled with dry nitrogen. A separate data acquisition system will support this apparatus. This system will contain a personal computer, video recorder, and monitor. Temperature, acceleration, winding speed, and video images will be controlled and recorded using the data acquisition system. Thus, the FPA will consist of two hardware packages, the fiber production assembly and the data acquisition rack. The primary objective of this test is to determine the effects of 1/6 g on the formation of continuous glass fiber made from simulated lunar soil. Baseline studies using the FPA on the ground will provide a reference for the 1/6 g studies. Of particular interest will be the effect of 1/6 g on the free fluid zone where the fiber exits the crucible. In the fiber spinning parlance this zone is known as the upper jet region, where the boundary slope is greater than one tenth. The properties of the resulting glass fiber will depend on the jet shape as well as distributions of velocity, temperature and tension within the jet. It is unknown at this time how 1/6 g will effect these parameters.
InGaAs detectors and FPA's for a large span of applications: design and material considerations
NASA Astrophysics Data System (ADS)
Vermeiren, J. P.; Merken, P.
2017-11-01
Compared with the other Infrared detector materials, such as HgCdTe (or MCT) and lead salts (e.g.: PbS, PbSe, PbSnTe, …), the history of InGaAs FPA's is not that old. Some 25 years ago the first linear detectors were used for space missions [1,2]. During the last 15-20 years InGaAs, grown lattice matched on InP, has become the work horse for the telecommunication industry [3] and later on for passive and active imagery in the SWIR range. For longer wavelengths than 1.7 μm, III-V materials are in strong competition with SWIR MCT and till now the performance of MCT is better than high In-content InGaAs. During the last years some alternatives based on quaternary materials [4] and on Superlattice structures [5] are making gradual progress in such a way that they can yield performing Focal planes in the (near) future. As the SWIR wavelengths range covers a large variety of applications, also the FPA characteristics and mainly the ROIC properties need to be adjusted to fulfil the mission requirements with the requested performance. Additionally one has to bear in mind that the nature of SWIR radiation is completely different from what is usually encountered in IR imaging. Whereas the signal of thermal imagery in the Middle Wavelength (MWIR: [3 - 5 μm]) or Long Wavelength (LWIR: [8 - 10 μm] or [8 - 12 μm]) band is characterized by a large DC pedestal, caused by objects at ambient temperature, and a small AC signal, due to the small temperature or emissivity variations, SWIR range imagery is characterized by a large dynamic range and almost no DC signal. In this sense the SWIR imagery is resembling more the nature of Visible and NIR imaging than that of thermal imagery.
Gorzsás, András; Sundberg, Björn
2014-01-01
Fourier transform infrared (FT-IR) spectroscopy is a fast, sensitive, inexpensive, and nondestructive technique for chemical profiling of plant materials. In this chapter we discuss the instrumental setup, the basic principles of analysis, and the possibilities for and limitations of obtaining qualitative and semiquantitative information by FT-IR spectroscopy. We provide detailed protocols for four fully customizable techniques: (1) Diffuse Reflectance Infrared Fourier Transform Spectroscopy (DRIFTS): a sensitive and high-throughput technique for powders; (2) attenuated total reflectance (ATR) spectroscopy: a technique that requires no sample preparation and can be used for solid samples as well as for cell cultures; (3) microspectroscopy using a single element (SE) detector: a technique used for analyzing sections at low spatial resolution; and (4) microspectroscopy using a focal plane array (FPA) detector: a technique for rapid chemical profiling of plant sections at cellular resolution. Sample preparation, measurement, and data analysis steps are listed for each of the techniques to help the user collect the best quality spectra and prepare them for subsequent multivariate analysis.
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Fast Uncooled Low Density FPA of VPD PbSe for Applications in Hyperspectral Imagery
2009-10-01
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Optical Correction Of Space-Based Telescopes Using A Deformable Mirror System
2016-12-01
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The Development and Evaluation of a Parent Empowerment Program for Family Peer Advocates
ERIC Educational Resources Information Center
Rodriguez, James; Olin, S. S.; Hoagwood, Kimberly E.; Shen, Sa; Burton, Geraldine; Radigan, Marleen; Jensen, Peter S.
2011-01-01
Family-to-family services are emerging as an important adjunctive service to traditional mental health care and a vehicle for improving parent engagement and service use in children's mental health services. In New York State, a growing workforce of Family Peer Advocates (FPA) is delivering family-to-family services. We describe the development…
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Dual band QWIP focal plane array
NASA Technical Reports Server (NTRS)
Gunapala, Sarath D. (Inventor); Choi, Kwong Kit (Inventor); Bandara, Sumith V. (Inventor)
2005-01-01
A quantum well infrared photodetector (QWIP) that provides two-color image sensing. Two different quantum wells are configured to absorb two different wavelengths. The QWIPs are arrayed in a focal plane array (FPA). The two-color QWIPs are selected for readout by selective electrical contact with the two different QWIPs or by the use of two different wavelength sensitive gratings.
75 FR 33610 - Application To Export Electric Energy; H.Q. Energy Services (U.S.) Inc.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-14
... DEPARTMENT OF ENERGY [OE Docket No. EA-182-C] Application To Export Electric Energy; H.Q. Energy... electric energy from the United States to Canada pursuant to section 202(e) of the Federal Power Act (FPA... transmit electric energy from the United States to Canada as a power marketer using existing international...
77 FR 23238 - Application To Export Electric Energy; Citigroup Energy Canada ULC
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-18
... wholesale market in interstate commerce or have a power supply system of its own on which its exports of... U.S. electric power supply system. Copies of this application will be made available, upon request... electric energy from the United States to Canada pursuant to section 202(e) of the Federal Power Act (FPA...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-16
... (FPA), proposing to study the feasibility of the Tuttle Creek Hydroelectric Project (Tuttle Creek Project or project) to be located at the U.S. Army Corps of Engineers' (Corps) Tuttle Creek Dam, on Big Blue River, near Manhattan, Riley County, Kansas. The sole purpose of a preliminary permit, if issued...
Code of Federal Regulations, 2011 CFR
2011-04-01
... section 212 of the FPA, access to the electric transmission system for the purposes of wholesale... on its transmission system. (5) The names of any other parties likely to provide transmission service... requirement by specifying a rate methodology (e.g., embedded or incremental cost) or by referencing an...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-06
... Power Act (FPA), proposing to study the feasibility of the Coffin Butte Pumped Storage Water Power... triangular earth and roller compacted concrete embankment; creating a 50-acre upper reservoir with a storage...); (2) a 6,300-foot-long, 60-foot-high oval earth and roller compacted concrete embankment; creating a...
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2011-10-31
... Machinery Co., Inc.; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments, Motions To Intervene, and Competing Applications On August 15, 2011, Windsor Machinery Co., Inc. filed an application for a preliminary permit, pursuant to section 4(f) of the Federal Power Act (FPA), proposing to...
77 FR 74472 - Application to Export Electric Energy; Energia Renovable S.C., LLC
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-14
... Renovable S.C., LLC AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of application. SUMMARY: Energia Renovable S.C., LLC (Energia Renovable) has applied for authority to transmit....C. 7151(b), 7172(f)) and require authorization under section 202(e) of the FPA (16 U.S.C.824a(e...
77 FR 34378 - PJM Interconnection, L.L.C.; Notice of Complaint
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-11
... Interconnection, L.L.C.; Notice of Complaint Take notice that on June 1, 2012, pursuant to section 206 of the Federal Power Act (FPA), 16 U.S.C. 824(e), PJM Interconnection, L.L.C. (PJM) filed proposed revisions to the Amended and Restated Operating Agreement of PJM Interconnection L.L.C. (Operating Agreement) to...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-25
...), filed an application for a successive preliminary permit, pursuant to section 4(f) of the Federal Power Act (FPA), proposing to study the feasibility of the Muskeget Channel Tidal Energy Project to be..., and one experimental turbine unit that would be used to test various open- bladed and helical tidal...
Acerbo, Alvin S; Miller, Lisa M
2009-08-01
Boron is found in everyday foods and drinking water in trace quantities. Boron exists as boric acid (BA) within plants and animals, where low levels have been linked to cancer incidence. However, this correlation is not well characterized. In this study, we examined the chemical and morphological effects of BA on human skin melanoma cells (SK-MEL28) using Fourier Transform InfraRed Imaging (FTIRI) with a Focal Plane Array (FPA) detector. Cells were grown under concentrations of BA ranging from 0 to 50 mM. Cell viability was determined after 1, 2, 3, 5, 7 and 10 days using trypan blue staining. With FTIRI, images of approximately twenty cells per time point per condition were collected. Principal components analysis (PCA) was used to evaluate changes in cell composition, with particular focus on the lipid, protein, and nucleic acid spectral components. Results from trypan blue staining revealed decreased cell viability as BA concentration increased. FTIRI data indicated that the protein and lipid contents (as indicated by the lipid/protein ratio) did not undergo substantial changes due to BA treatment. In contrast, the nucleic acid/protein ratio significantly decreased with BA treatment. PCA results showed an increase in beta-sheet protein at higher concentrations of BA (12.5, 25, and 50 mM). Together, these results suggest that high concentrations of BA have an anti-proliferative effect and show signs consistent with apoptosis.
Antennas for Terahertz Applications: Focal Plane Arrays and On-chip Non-contact Measurement Probes
NASA Astrophysics Data System (ADS)
Trichopoulos, Georgios C.
The terahertz (THz) band provides unique sensing opportunities that enable several important applications such as biomedical imaging, remote non-destructive inspection of packaged goods, and security screening. THz waves can penetrate most materials and can provide unique spectral information in the 0.1--10 THz band with high resolution. In contrast, other imaging modalities, like infrared (IR), suffer from low penetration depths and are thus not attractive for non-destructive evaluation. However, state-of-the-art THz imaging systems typically employ mechanical raster scans using a single detector to acquire two-dimensional images. Such devices tend to be bulky and complicated due to the mechanical parts, and are thus rather expensive to develop and operate. Thus, large-format (e.g. 100x100 pixels) and all-electronics based THz imaging systems are badly needed to alleviate the space, weight and power (SWAP) factors and enable cost effective utilization of THz waves for sensing and high-data-rate communications. In contrast, photonic sensors are very compact because light can couple directly to the photodiode without residing to radiation coupling topologies. However, in the THz band, due to the longer wavelengths and much lower photon energies, highly efficient antennas with optimized input impedance have to be integrated with THz sensors. Here, we implement novel antenna engineering techniques that are optimized to take advantage of recent technological advances in solid-state THz sensing devices. For example, large-format focal plane arrays (FPAs) have been the Achilles' heel of THz imaging systems. Typically, optical components (lenses, mirrors) are employed in order to improve the optical performance of FPAs, however, antenna sensors suffer from degraded performance when they are far from the optical axis, thus minimizing the number of useful FPA elements. By modifying the radiation pattern of FPA antennas we manage to alleviate the off-axis aberration. Additionally, a butterfly-shaped antenna layout is introduced that enables broadband imaging. The alternative design presented here, allows for video-rate imaging in the 0.6--1.2 THz band and maintains a small antenna footprint, resulting in densely packed FPAs. In both antenna designs, we optimize the impedance matching between the antennas and the integrated electronic devices, thus achieving optimum responsivity levels for high sensitivity and low noise performance. Subsequently, we present the design details of the first THz camera and the first THz camera images captured. With the realized THz camera, imaging of concealed objects is achieved with <1mm diffraction limited spatial resolution. Moreover, motivated by the THz camera's real-time image acquisition, we developed the first camera-based THz computer tomography system that allows rapid cross-sectional imaging (˜2 min). For the design and analysis of the THz camera performance, we developed an in-house hybrid electromagnetic model, combining full-wave and high-frequency computational methods. The antenna radiation and impedance computation is first carried out using full-wave modeling of the FPA. Subsequently, we employ scalar diffraction theory to compute the field distribution at any point in space. Thus, the hybrid electromagnetic model allows fast and accurate design of THz antennas and modeling of the complete THz imaging system. Finally, motivated by the novel THz antenna layouts and the quasioptical techniques, we developed a novel non-contact probe measurement method for on-chip device characterization. In the THz regime, traditional contact probes are too small and fragile, thus inhibiting accurate and reliable circuit measurements. By integrating the device under test (DUT) with THz antennas that act as the measurement probes, we may couple the incident and reflected signal from and to the network analyzer without residing to any physical connection.
75 FR 16449 - Central Transmission, LLC v. PJM Interconnection L.L.C.; Notice of Complaint
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-01
... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EL10-52-000] Central Transmission, LLC v. PJM Interconnection L.L.C.; Notice of Complaint March 26, 2010. Take notice that on March... Interconnection L.L.C. (PJM) pursuant to section 206 of the Federal Power Act (FPA), alleging that Schedule 6 of...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-06
... Cable, LLC; Notice of Institution of Section 206 Investigation and Refund Effective Date July 30, 2010...-116-000, pursuant to section 206 of the Federal Power Act (FPA), 16 U.S.C. 824e, concerning the justness and reasonableness of rates proposed by Trans Bay Cable, LLC (Trans Bay) in [[Page 47589
Cetacean Social Behavioral Response to Sonar Exposure
2015-09-30
Lam FPA, Tyack PLT, Miller PJO (in review). Disturbance-specific social responses in long-finned pilot whales, Globicephala melas . Fieldwork...the social behavioral response of long-finned pilot whales (Globicephala melas ) revealed that a unifying characteristic of their behavioral response...Globicephala melas . 6 Visser F. et al. (in review). Vocal foragers and silent crowds: the socio-behavioural context of long- finned pilot whale
Federal Register 2010, 2011, 2012, 2013, 2014
2013-10-09
... maintained for the Y amended by HREA. generation of electric power and uses for such generation only the... Statutory provision Description (Y/N) FPA 30(a)(3)(A), as amended The conduit the facility uses is a tunnel, canal, pipeline, Y by HREA. aqueduct, flume, ditch, or similar manmade water conveyance that is operated...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-30
... maintained for Y HREA. the generation of electric power and uses for such generation only the hydroelectric... provision Description (Y/N) FPA 30(a)(3)(A), as amended by HREA.. The conduit the facility uses is a tunnel, canal, pipeline, Y aqueduct, flume, ditch, or similar manmade water conveyance that is operated for the...
78 FR 70035 - Idaho Power Company; Notice of Initiation of Proceeding and Refund Effective Date
Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-22
... Company; Notice of Initiation of Proceeding and Refund Effective Date On November 13, 2013, the Commission...-based rates proposed by Idaho Power Company. Idaho Power Company, 145 FERC ] 61,122 (2013). The refund effective date in Docket No. EL14-3-000, established pursuant to section 206(b) of the FPA, will be the date...
78 FR 69411 - Idaho Power Company; Notice of Initiation of Proceeding and Refund Effective Date
Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-19
... Company; Notice of Initiation of Proceeding and Refund Effective Date On November 13, 2013, the Commission...-based rates proposed by Idaho Power Company. Idaho Power Company, 145 FERC ] 61,122 (2013). The refund effective date in Docket No. EL14-3-000, established pursuant to section 206(b) of the FPA, will be the date...
The Impact of Emerging Technologies on Future Air Capabilities
1999-12-01
ferroelectric FPAs (60). More advanced FPA technologies include quantum well IR photodetectors ( QWIPS ) and strained layer superlattices. Significant...microspacecraft. Expected benefits include enhanced handling qualities, vibration suppression, alleviation of noise and vibration and monitoring of vehicle...of fatigue loads, cabin vibration and both internal and external noise , as well as contributing to enhanced handling. This would result in better
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-30
... California; and (14) appurtenant facilities. The project would be a closed-loop system using groundwater and... application for a successive preliminary permit, pursuant to section 4(f) of the Federal Power Act (FPA... power tunnel; (6) a 30-foot-diameter, 1,200-foot-long vertical shaft; (7) a 30-foot-diameter, 1,000-foot...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-27
... to section 4(f) of the Federal Power Act (FPA), proposing to study the feasibility of the East Foreland Tidal Energy Project (East Foreland project) to be located in Cook Inlet in the vicinity of... from the module site to a shore station on the west coast of the Kenai Peninsula; (3) an approximately...
Liu, Yun-Tao; Luo, Ze-Yu; Long, Chuan-Nan; Wang, Hai-Dong; Long, Min-Nan; Hu, Zhong
2011-10-01
To produce cellulolytic enzyme efficiently, Penicillium decumbens strain L-06 was used to prepare mutants with ethyl methane sulfonate (EMS) and UV-irradiation. A mutant strain ML-017 is shown to have a higher cellulase activity than others. Box-Behnken's design (BBD) and response surface methodology (RSM) were adopted to optimize the conditions of cellulase (filter paper activity, FPA) production in strain ML-017 by solid-state fermentation (SSF) with rice bran as the substrate. And the result shows that the initial pH, moisture content and culture temperature all have significant effect on the production of cellulase. The optimized condition shall be initial pH 5.7, moisture content 72% and culture temperature 30°C. The maximum cellulase (FPA) production was obtained under the optimized condition, which is 5.76 IU g(-1), increased by 44.12% to its original strain. It corresponded well with the calculated results (5.15 IU g(-1)) by model prediction. The result shows that both BBD and RSM are the cellulase optimization methods with good prospects. Copyright © 2011 Elsevier B.V. All rights reserved.
ATTICA family of thermal cameras in submarine applications
NASA Astrophysics Data System (ADS)
Kuerbitz, Gunther; Fritze, Joerg; Hoefft, Jens-Rainer; Ruf, Berthold
2001-10-01
Optronics Mast Systems (US: Photonics Mast Systems) are electro-optical devices which enable a submarine crew to observe the scenery above water during dive. Unlike classical submarine periscopes they are non-hull-penetrating and therefore have no direct viewing capability. Typically they have electro-optical cameras both for the visual and for an IR spectral band with panoramic view and a stabilized line of sight. They can optionally be equipped with laser range- finders, antennas, etc. The brand name ATTICA (Advanced Two- dimensional Thermal Imager with CMOS-Array) characterizes a family of thermal cameras using focal-plane-array (FPA) detectors which can be tailored to a variety of requirements. The modular design of the ATTICA components allows the use of various detectors (InSb, CMT 3...5 μm , CMT 7...11 μm ) for specific applications. By means of a microscanner ATTICA cameras achieve full standard TV resolution using detectors with only 288 X 384 (US:240 X 320) detector elements. A typical requirement for Optronics-Mast Systems is a Quick- Look-Around capability. For FPA cameras this implies the need for a 'descan' module which can be incorporated in the ATTICA cameras without complications.
NASA Astrophysics Data System (ADS)
Escribano, Rafel; Gonzàlez-Solís, Sergi
2018-01-01
The dilepton invariant mass spectra and integrated branching ratios of the single and double Dalitz decays {\\mathscr{P}}\\to {{{l}}}+{{{l}}}-{{γ }} and {\\mathscr{P}}\\to {{{l}}}+{{{l}}}-{{{l}}}+{{{l}}}- ({\\mathscr{P}}={{{π }}}0,{{η }},{{{η }}}\\prime; {{l}}={{e}} or {{μ }}) are predicted by means of a data-driven approach based on the use of rational approximants applied to {{{π }}}0,{{η }} and {{{η }}}\\prime transition form factor experimental data in the space-like region. Supported by the FPI scholarship BES-2012-055371 (S.G-S), the Secretaria d’Universitats i Recerca del Departament d’Economia i Coneixement de la Generalitat de Catalunya under grant 2014 SGR 1450, the Ministerio de Ciencia e Innovación under grant FPA2011-25948, the Ministerio de Economía y Competitividad under grants CICYT-FEDER-FPA 2014-55613-P and SEV-2012-0234, the Spanish Consolider-Ingenio 2010 Program CPAN (CSD2007-00042), and the European Commission under program FP7-INFRASTRUCTURES-2011-1 (283286) S.G-S also Received Support from the CAS President’s International Fellowship Initiative for Young International Scientist (2017PM0031)
Lee, Chulsung; Lee, Dustin; Darling, Cynthia L; Fried, Daniel
2010-01-01
The high transparency of dental enamel in the near-infrared (NIR) at 1310 nm can be exploited for imaging dental caries without the use of ionizing radiation. The objective of this study is to determine whether the lesion contrast derived from NIR imaging in both transmission and reflectance can be used to estimate lesion severity. Two NIR imaging detector technologies are investigated: a new Ge-enhanced complementary metal-oxide-semiconductor (CMOS)-based NIR imaging camera, and an InGaAs focal plane array (FPA). Natural occlusal caries lesions are imaged with both cameras at 1310 nm, and the image contrast between sound and carious regions is calculated. After NIR imaging, teeth are sectioned and examined using polarized light microscopy (PLM) and transverse microradiography (TMR) to determine lesion severity. Lesions are then classified into four categories according to lesion severity. Lesion contrast increases significantly with lesion severity for both cameras (p<0.05). The Ge-enhanced CMOS camera equipped with the larger array and smaller pixels yields higher contrast values compared with the smaller InGaAs FPA (p<0.01). Results demonstrate that NIR lesion contrast can be used to estimate lesion severity.
In vitro near-infrared imaging of occlusal dental caries using a germanium-enhanced CMOS camera
NASA Astrophysics Data System (ADS)
Lee, Chulsung; Darling, Cynthia L.; Fried, Daniel
2010-02-01
The high transparency of dental enamel in the near-infrared (NIR) at 1310-nm can be exploited for imaging dental caries without the use of ionizing radiation. The objective of this study was to determine whether the lesion contrast derived from NIR transillumination can be used to estimate lesion severity. Another aim was to compare the performance of a new Ge enhanced complementary metal-oxide-semiconductor (CMOS) based NIR imaging camera with the InGaAs focal plane array (FPA). Extracted human teeth (n=52) with natural occlusal caries were imaged with both cameras at 1310-nm and the image contrast between sound and carious regions was calculated. After NIR imaging, teeth were sectioned and examined using more established methods, namely polarized light microscopy (PLM) and transverse microradiography (TMR) to calculate lesion severity. Lesions were then classified into 4 categories according to the lesion severity. Lesion contrast increased significantly with lesion severity for both cameras (p<0.05). The Ge enhanced CMOS camera equipped with the larger array and smaller pixels yielded higher contrast values compared with the smaller InGaAs FPA (p<0.01). Results demonstrate that NIR lesion contrast can be used to estimate lesion severity.
Lee, Chulsung; Lee, Dustin; Darling, Cynthia L.; Fried, Daniel
2010-01-01
The high transparency of dental enamel in the near-infrared (NIR) at 1310 nm can be exploited for imaging dental caries without the use of ionizing radiation. The objective of this study is to determine whether the lesion contrast derived from NIR imaging in both transmission and reflectance can be used to estimate lesion severity. Two NIR imaging detector technologies are investigated: a new Ge-enhanced complementary metal-oxide-semiconductor (CMOS)-based NIR imaging camera, and an InGaAs focal plane array (FPA). Natural occlusal caries lesions are imaged with both cameras at 1310 nm, and the image contrast between sound and carious regions is calculated. After NIR imaging, teeth are sectioned and examined using polarized light microscopy (PLM) and transverse microradiography (TMR) to determine lesion severity. Lesions are then classified into four categories according to lesion severity. Lesion contrast increases significantly with lesion severity for both cameras (p<0.05). The Ge-enhanced CMOS camera equipped with the larger array and smaller pixels yields higher contrast values compared with the smaller InGaAs FPA (p<0.01). Results demonstrate that NIR lesion contrast can be used to estimate lesion severity. PMID:20799842
NASA Astrophysics Data System (ADS)
Lee, Chulsung; Lee, Dustin; Darling, Cynthia L.; Fried, Daniel
2010-07-01
The high transparency of dental enamel in the near-infrared (NIR) at 1310 nm can be exploited for imaging dental caries without the use of ionizing radiation. The objective of this study is to determine whether the lesion contrast derived from NIR imaging in both transmission and reflectance can be used to estimate lesion severity. Two NIR imaging detector technologies are investigated: a new Ge-enhanced complementary metal-oxide-semiconductor (CMOS)-based NIR imaging camera, and an InGaAs focal plane array (FPA). Natural occlusal caries lesions are imaged with both cameras at 1310 nm, and the image contrast between sound and carious regions is calculated. After NIR imaging, teeth are sectioned and examined using polarized light microscopy (PLM) and transverse microradiography (TMR) to determine lesion severity. Lesions are then classified into four categories according to lesion severity. Lesion contrast increases significantly with lesion severity for both cameras (p<0.05). The Ge-enhanced CMOS camera equipped with the larger array and smaller pixels yields higher contrast values compared with the smaller InGaAs FPA (p<0.01). Results demonstrate that NIR lesion contrast can be used to estimate lesion severity.
In vitro near-infrared imaging of occlusal dental caries using germanium enhanced CMOS camera.
Lee, Chulsung; Darling, Cynthia L; Fried, Daniel
2010-03-01
The high transparency of dental enamel in the near-infrared (NIR) at 1310-nm can be exploited for imaging dental caries without the use of ionizing radiation. The objective of this study was to determine whether the lesion contrast derived from NIR transillumination can be used to estimate lesion severity. Another aim was to compare the performance of a new Ge enhanced complementary metal-oxide-semiconductor (CMOS) based NIR imaging camera with the InGaAs focal plane array (FPA). Extracted human teeth (n=52) with natural occlusal caries were imaged with both cameras at 1310-nm and the image contrast between sound and carious regions was calculated. After NIR imaging, teeth were sectioned and examined using more established methods, namely polarized light microscopy (PLM) and transverse microradiography (TMR) to calculate lesion severity. Lesions were then classified into 4 categories according to the lesion severity. Lesion contrast increased significantly with lesion severity for both cameras (p<0.05). The Ge enhanced CMOS camera equipped with the larger array and smaller pixels yielded higher contrast values compared with the smaller InGaAs FPA (p<0.01). Results demonstrate that NIR lesion contrast can be used to estimate lesion severity.
NASA Technical Reports Server (NTRS)
Gallegos, Gregory L.; Peterson, Barbara V.; Brown, Christopher S.; Guikema, James A.
1995-01-01
Previous experiments from our lab have shown that seeds of sweet clover, when germinated and grown within the Fluid Processing Apparatus (FPA) on a slow rotating clinostat produce significantly greater levels of the volatile stress hormone, ethylene, when compared to seeds treated the same but without clinorotation. In both conditions, carbon dioxide levels reached high levels and seedling growth was inhibited. However, clinorotation inhibited growth to a greater extent. To help determine to what extent microgravity influences stress ethylene production and to what extent ethylene inhibits seedling growth, we have extended the above experiments by growing sweet clover in the presence of aminooxyacetic acid (AOA) and silver nitrate (AgNO3), inhibitors of stress ethylene biosynthesis and action, respectively. Seeds of sweet clover were germinated and grown for five days in the FPA under two gravity conditions: under stationary conditions on Earth and in microgravity onboard the space shuttle, Discovery (STS-63), which launched Feb. 3, 1995. Upon recovery, gas samples were aspirated from the growth chambers and carbon dioxide and ethylene concentrations were measured using a gas chromatograph. Then the tissue was weighed, photographed and fixed, and is current undergoing further morphological and microscopic characterization.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-18
... August 11, 2010, the Commission issued an order that instituted a proceeding in Docket No. EL10-73-000, pursuant to section 206 of the Federal Power Act (FPA), 16 USC 824e, to determine whether the J.P. Morgan Sellers' \\1\\ market-based rate authority in the Cleco Corporation, Inc. balancing authority area remains...
Code of Federal Regulations, 2010 CFR
2010-04-01
... tribal laws or custom; (e) Contracts or agreements that do not convey exclusive or nearly exclusive... Indian Gaming Commission under the Indian Gaming Regulatory Act, 25 U.S.C. 2701 et seq., and the...) FERC has made the finding under section 4(e) of the FPA (16 U.S.C. 797(e)) that the license or...
1997 Report to the Congress on Ballistic Missile Defense.
1997-10-01
Infrared Arrays • Quantum Well Infrared Photodector (QWIP) Focal Plane Array (FPA) • Staring Si Impurity Band Conduction Extremely Sensitive Focal...to be flown on STRV lc/d include a Quantum Well Infrared Photometer (QWIP) sensor and a multifunctional compos- ite structure. The Space Technology...Peoples Republic of China Platinum Silicide Quick Reaction Program Quick Response Program Quantum Well Infrared Photometer Research and
43 CFR 45.1 - What is the purpose of this part, and to what license proceedings does it apply?
Code of Federal Regulations, 2010 CFR
2010-10-01
... prescriptions that the Department of the Interior (DOI) may develop for inclusion in a hydropower license issued... apply to recommendations that DOI may submit to FERC under FPA section 10(a) or (j), 16 U.S.C. 803(a... a hydropower license. Where DOI and either or both of these other Departments develop conditions or...
Optical Readout System for Bi-Material Terahertz Sensors
2011-09-01
CCD Charged-Coupled Device DFG Difference-Frequency Generation FOV Field of View FPA Focal Plane Array fps Frames Per Second FTIR Fourier ...techniques in the THz range may be classified as either coherent or incoherent. Basically, coherent detection measures the amplitude and phase of the field...using a lock-in amplifier. In a piezoresistive detector, two electrodes are connected to two deformable temperature–sensitive legs. Monitoring the
Jeremy D. Groom
2013-01-01
Studies over the past 40 years have established that riparian buff er retention along streams protects against stream temperature increase. Th is protection is neither universal nor complete; some buff ered streams still warm, while other streamsâ temperatures remain stable. Oregon Department of Forestry developed riparian rules in the Forest Practices Act (FPA) to...
43 CFR 45.1 - What is the purpose of this part, and to what license proceedings does it apply?
Code of Federal Regulations, 2011 CFR
2011-10-01
... prescriptions that the Department of the Interior (DOI) may develop for inclusion in a hydropower license issued... apply to recommendations that DOI may submit to FERC under FPA section 10(a) or (j), 16 U.S.C. 803(a... a hydropower license. Where DOI and either or both of these other Departments develop conditions or...
Status of two-color and large format HgCdTe FPA technology at Raytheon Vision Systems
NASA Astrophysics Data System (ADS)
Smith, E. P. G.; Bornfreund, R. E.; Kasai, I.; Pham, L. T.; Patten, E. A.; Peterson, J. M.; Roth, J. A.; Nosho, B. Z.; De Lyon, T. J.; Jensen, J. E.; Bangs, J. W.; Johnson, S. M.; Radford, W. A.
2006-02-01
Raytheon Vision Systems (RVS) is developing two-color and large format single color FPAs fabricated from molecular beam epitaxy (MBE) grown HgCdTe triple layer heterojunction (TLHJ) wafers on CdZnTe substrates and double layer heterojunction (DLHJ) wafers on Si substrates, respectively. MBE material growth development has resulted in scaling TLHJ growth on CdZnTe substrates from 10cm2 to 50cm2, long-wavelength infrared (LWIR) DLHJ growth on 4-inch Si substrates and the first demonstration of mid-wavelength infrared (MWIR) DLHJ growth on 6-inch Si substrates with low defect density (<1000cm -2) and excellent uniformity (composition<0.1%, cut-off wavelength Δcenter-edge<0.1μm). Advanced FPA fabrication techniques such as inductively coupled plasma (ICP) etching are being used to achieve high aspect ratio mesa delineation of individual detector elements with benefits to detector performance. Recent two-color detectors with MWIR and LWIR cut-off wavelengths of 5.5μm and 10.5μm, respectively, exhibit significant improvement in 78K LW performance with >70% quantum efficiency, diffusion limited reverse bias dark currents below 300pA and RA products (zero field-of-view, +150mV bias) in excess of 1×103 Ωcm2. Two-color 20μm unit-cell 1280×720 MWIR/LWIR FPAs with pixel response operability approaching 99% have been produced and high quality simultaneous imaging of the spectral bands has been achieved by mating the FPA to a readout integrated circuit (ROIC) with Time Division Multiplexed Integration (TDMI). Large format mega pixel 20μm unit-cell 2048×2048 and 25μm unit-cell 2560×512 FPAs have been demonstrated using DLHJ HgCdTe growth on Si substrates in the short wavelength infrared (SWIR) and MWIR spectral range. Recent imaging of 30μm unit-cell 256×256 LWIR FPAs with 10.0-10.7μm 78K cut-off wavelength and pixel response operability as high as 99.7% show the potential for extending HgCdTe/Si technology to LWIR wavelengths.
Development of miniature moving magnet cryocooler SX040
NASA Astrophysics Data System (ADS)
Rühlich, I.; Mai, M.; Rosenhagen, C.; Schreiter, A.; Möhl, C.
2011-06-01
State of the art high performance cooled IR systems need to have more than just excellent E/O performance. Minimum size weight and power (SWaP) are the design goals to meet our forces' mission requirements. Key enabler for minimum SWaP of IR imagers is the operation temperature of the focal plane array (FPA) employed. State of the art MCT or InAsSb nBn technology has the potential to rise the FPA temperature from 77 K to 130-150 K (high operation temperature HOT) depending on the specific cut-off wavelength. Using a HOT FPA will significantly lower SWaP and keep those parameters finally dominated by the employed cryocooler. Therefore compact high performance cryocoolers are mandatory. For highest MTTF life AIM developed its Flexure Bearing Moving Magnet product family "SF". Such coolers achieve more than 20000 h MTTF with Stirling type expander and more than 5 years MTTF life with Pulse Tube coldfinger (like for Space applications). To keep the high lifetime potential but to significantly improve SWaP AIM is developing its "SX" type cooler family. The new SX040 cooler incorporates a highly efficient dual piston Moving Magnet driving mechanism resulting in very compact compressor of less than 100mm length. The cooler's high lifetime is also achieved by placing the coils outside the helium vessel as usual for moving magnet motors. The mating ¼" expander is extremely compact with less than 63 mm length. This allows a total dewar length from optical window to expander warm end of less than 100 mm even for large cold shields. The cooler is optimized for HOT detectors with operating temperatures exceeding 95 K. While this kind of cooler is the perfect match for many applications, handheld sights or targeting devices for the dismounted soldier are even more challenging with respect to SWaP. AIM therefore started to develop an even smaller cooler type with single piston and balancer. This paper gives an overview on the development of this new compact cryocooler. Technical details and performance data will be shown.
Urinary coagulation-fibrinolysis, kallirein-kinin systems and kininase in cases of preclampsia.
Mutoh, S; Kobayashi, M; Hirata, J; Itoh, N; Maki, M; Komatsu, Y; Yoshida, A; Sasa, H; Kuroda, K; Kikuchi, Y
1992-01-01
Urinary kallikrein and kallikrein activity significantly decreased in cases of preeclampsia (u-kall./CRE.index 42.39 +/- 9.66 ng/mg, u-kall. act./CRE.index 0.26 +/- 0.06 ng/min/mg), and urinary kininase II and kininase activity significantly increased (u-kininase/CRE.index 10.91 +/- 1.26 x 10(-3) IU/min/mg, u-kininase act./CRE.index 506.37 +/- 178.45 pg/min/mg) when compared with those of normal gravidas from 28 weeks to 42 weeks of gestation (u-kall./CRE.index 189.31 +/- 14.17 ng/mg, u-kall. act./CRE index 1.08 +/- 0.10 ng/min/mg, u-kininase/CRE.index 6.24 +/- 0.31 x 10(-3) IU/min/mg, u-kininase act./CRE.index 15.64 +/- 0.10 pg/min/mg). Urinary FPA, B beta 5-42, alpha 2-PI, and alpha 2PI-plasmin-complex (PIC) significantly increased in preeclampsia (u-FPA/CRE.index 23.59 +/- 8.47 ng/mg, u-B beta/CRE.index 105.26 +/- 29.30 ng/mg, u-alpha 2PI/CRE.index 121.53 +/- 43.57 ng/mg, u-PIC/CRE index 278.39 +/- 60.50 ng/mg) when compared with those of normal control group (u-FPA/CRE.index 0.92 +/- 0.04 ng/mg, u-B beta/CRE.index 12.15 +/- 0.44 ng/mg, u-alpha 2PI/CRE.index 4.18 +/- 0.33 ng/mg, u-PIC/CRE.index 5.98 +/- 1.15 ng/mg). Urinary urokinase markedly increased and urinary D-dimer was detected in severe cases of preeclampsia (u-UK/CRE.index 58.20 +/- 43.69 ng/mg, u-D-dimer 54.76 +/- 9.89 ng/ml) when compared with those of normal control group. These findings suggest that deficiency in urinary kinin excretion may induce hypertension in addition to the changes of urinary coagulation-fibrinolysis system that represents the occurrence of either the endothelial cell injury in the glomerulus or the renal tulbular damage in mild cases of preeclampsia, eventually resulting in the intra-renal vascular coagulation.
Lightweight uncooled TWS equipped with catadioptric optics and microscan mechanism
NASA Astrophysics Data System (ADS)
Bergeron, A.; Jerominek, H.; Doucet, M.; Lagacé, F.; Desnoyers, N.; Bernier, S.; Mercier, L.; Boucher, M.-A.; Jacob, M.; Alain, C.; Pope, T. D.; Laou, P.
2006-05-01
A rugged lightweight thermal weapon sight (TWS) prototype was developed at INO in collaboration with DRDC-Valcartier. This TWS model is based on uncooled bolometer technology, ultralight catadioptric optics, ruggedized mechanics and electronics, and extensive onboard processing capabilities. The TWS prototype operates in a single 8-12 μm infrared (IR) band. It is equipped with a unique lightweight athermalized catadioptric objective and a bolometric IR imager with an INO focal plane array (FPA). Microscan technology allows the use of a 160 x 120 pixel FPA with a pitch of 50 μm to achieve a 320 × 240 pixel resolution image thereby avoiding the size (larger optics) and cost (expensive IR optical components) penalties associated with the use of larger format arrays. The TWS is equipped with a miniature shutter for automatic offset calibration. Based on the operation of the FPA at 100 frames per second (fps), real-time imaging with 320 x 240 pixel resolution at 25 fps is available. This TWS is also equipped with a high resolution (857 x 600 pixels) OLED color microdisplay and an integrated wireless digital RF link. The sight has an adjustable and selectable electronic reticule or crosshair (five possible reticules) and a manual focus from 5 m to infinity standoff distance. Processing capabilities are added to introduce specific functionalities such as image inversion (black hot and white hot), image enhancement, and pixel smoothing. This TWS prototype is very lightweight (~ 1100 grams) and compact (volume of 93 cubic inches). It offers human size target detection at 800 m and recognition at 200 m (Johnson criteria). With 6 Li AA batteries, it operates continuously for 5 hours and 20 minutes at room temperature. It can operate over the temperature range of -30 °C to +40 °C and its housing is completely sealed. The TWS is adapted to weaver or Picatinny rail mounting. The overall design of the TWS prototype is based on feedbacks of users to achieve improved user-friendly (e.g. no pull-down menus and no electronic focusing) and ergonomic (e.g. locations of buttons) features.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Michael Viola, J. Edwards, T. Brown, L. Dudek, R. Ellis, P. Heitzenroeder, R. Strykowsky and Michael Cole
The National Compact Stellarator Experiment (NCSX) was a collaborative effort between ORNL and PPPL. PPPL provided the assembly techniques with guidance from ORNL to meet design criteria. The individual vacuum vessel segments, modular coils, trim coils, and toroidal field coils components were delivered to the Field Period Assembly (FPA) crew who then would complete the component assemblies and then assemble the final three field period assemblies, each consisting of two sets of three modular coils assembled over a 120o vacuum vessel segment with the trim coils and toroidal field coils providing the outer layer. The requirements for positioning the modularmore » coils were found to be most demanding. The assembly tolerances required for accurate positioning of the field coil windings in order to generate sufficiently accurate magnetic fields strained state of the art techniques in metrology and alignment and required constant monitoring of assembly steps with laser trackers, measurement arms, and photogrammetry. The FPA activities were being performed concurrently while engineering challenges were being resolved. For example, it was determined that high friction electrically isolated shims were needed between the modular coil interface joints and low distortion welding was required in the nose region of those joints. This took months of analysis and development yet the assembly was not significantly impacted because other assembly tasks could be performed in parallel with ongoing assembly tasks as well as tasks such as advance tooling setup preparation for the eventual welding tasks. The crew technicians developed unique, accurate time saving techniques and tooling which provided significant cost and schedule savings. Project management displayed extraordinary foresight and every opportunity to gain advanced knowledge and develop techniques was taken advantage of. Despite many risk concerns, the cost and schedule performance index was maintained nearly 1.0 during the assembly phase until project cancellation. In this paper, the assembly logic, the engineering challenges, solutions to those challenges and some of the unique and clever assembly techniques, will be presented.« less
Analysis, testing, and operation of the MAGI thermal control system
DOE Office of Scientific and Technical Information (OSTI.GOV)
Yi, Sonny; Hall, Jeffrey L.; Kasper, Brian P.
2014-01-29
The Aerospace Corporation has completed the development of the Mineral and Gas Identifier (MAGI) sensor - an airborne multi-spectral infrared instrument that is designed to discriminate surface composition and to detect gas emissions from the environment. Sensor performance was demonstrated in a series of flights aboard a Twin Otter aircraft in December 2011 as a stepping stone to a future satellite sensor design. To meet sensor performance requirements the thermal control system was designed to operate the HgCdTe focal plane array (FPA) at 50 K with a 1.79 W heat rejection load to a 44.7 K sink and the opticalmore » assembly at 100 K with a 7.5 W heat load to a 82.3 K sink. Two commercial off-theshelf (COTS) Sunpower Stirling cryocoolers were used to meet the instrument’s cooling requirements. A thermal model constructed in Thermal Desktop was used to run parametric studies that guided the mechanical design and sized the two cryocoolers. This paper discusses the development, validation, and operation of the MAGI thermal control system. Detailed energy balances and temperature predictions are presented for various test cases to demonstrate the utility and accuracy of the thermal model. Model inputs included measured values of heat lift as a function of input power and cold tip temperature for the two cryocoolers. These measurements were also used to make predictions of the cool-down behavior from ambient conditions. Advanced heater software was developed to meet unique requirements for both sensor cool-down rate and stability at the set point temperatures.« less
3S2: Behavioral Response Studies of Cetaceans to Navy Sonar Signals in Norwegian Waters
2013-09-30
exposures of killer (Orcinus orca), long-finned pilot (Globicephala melas ), and sperm whales (Physeter macrocephalus) to naval sonar. Aquatic Mammals 38...pilot whales (Globicephala melas ). Marine Mammal Science. [in review, refereed] 8 Kvadsheim, PH, Miller, PJO, Tyack, P, Sivle, LD, Lam, FPA, and...killer (Orcinus orca), long-finned pilot (Globicephala melas ), and sperm whales (Physeter macrocephalus) to naval sonar. Aquatic Mammals 38: 362-401
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-31
... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EL14-16-000] Newmont Nevada Energy Investment LLC v. Sierra Pacific Power Company; Notice of Complaints Take notice that on December 23, 2013, pursuant to sections 206 and 306 of the Federal Power Act (FPA), 16 U.S.C. 824e, and 825e and Rule 206 of the Rules of Practice and...
Ballistic Missile Defense Glossary Version 3.0.
1997-06-01
The suppression of background noise for the improvement of an object signal. Battlefield Area Evaluation (USA term). Best and Final Offer...field of the lens are focused. An FPA is a matrix of photon sensitive detectors which, when combined with low noise preamplifiers, provides image data...orbital planes with an orbit period of 12 hours at 10,900 nautical miles altitude. Each satellite transmits three L-band, pseudo-random noise -coded
Computer Simulation of a 155-mm Projectile in a Scat Gun Assembly
2008-09-01
piston increases its kinetic energy as it is displaced a distance X. X X X MpsV2s /2 = f((P- vRT )/(Lpw -X))A - F)dx = (- vRT /(Lpw - X))AdY + f(PA -F...piston is displaced x, the critical displacement can be calculated using the Ideal Gas Law PV = vRT . YD = vRT /(A(Lp;v - x,i)) (ALpwv - x(,.ij
Promotion of adolescent reproductive health and healthy living. Malaysia.
1999-12-01
This article discusses a 3-year project, "Promotion of Adolescent Reproductive Health and Healthy Living," which was implemented by the Federation of Family Planning Associations, Malaysia. The project seeks to achieve the following: 1) development of a reproductive health of adolescent module (RHAM) for trainers and educators; 2) training of trainers; 3) sharing of adolescent reproductive health experiences in Asian countries; and 4) setting up three service models in Sabah, Selangor, and Terengganu to provide reproductive health (RH) care to adolescents and youth. The first part of the RHAM with the trainer's manual has been finalized and will be tested in a workshop. The second part, a teacher's guide, is under preparation. A series of training on the use of the RHAM will be conducted including a 5-day national workshop, which will be followed by several state level workshops. The three service models being set up have specific orientations. The Sabah model is putting up a youth clinic for adolescents within its clinic network. The Selangor model is developing a Youth Resource Center for training and youth involvement in RH activities. Lastly, the Terengganu family planning association (FPA) has developed a Youth Center web site, which features the history, mission, and activities of the Terengganu FPA.
The Sentinel-4 UVN focal plane assemblies
NASA Astrophysics Data System (ADS)
Hinger, Jürgen; Hohn, Rüdiger; Gebhardt, Eyk; Reichardt, Jörg
2017-09-01
The Sentinel-4 UVN Instrument is a dispersive imaging spectrometer covering the UV-VIS and the NIR wavelength. It is developed and built under an ESA contract by an industrial consortium led by Airbus Defence and Space. It will be accommodated on board of the MTG-S (Meteosat Third Generation - Sounder) satellite that will be placed in a geostationary orbit over Europe sampling data for generating two-dimensional maps of a number of atmospheric trace gases. The incoming light is dispersed by reflective gratings and detected by the two (UVVIS and NIR) CCDs mounted inside the focal plane assemblies. Both CCD detectors acquire spectral channels and spatial sampling in two orthogonal directions and will be operated at about 215 K mainly to minimize random telegraph signal effects and to reduce dark current. Stringent detector temperature as well as alignment stability requirements of less than +/-0.1 K per day respectively of less than 2 micrometers/2 arcseconds from ground to orbit are driving the FPA thermo-mechanical design. A specific FPA design feature is the redundant LED-calibration system for bad pixel detection as well as pixel gain and linearity monitoring. This paper reports on the design and qualification of the Focal Plane Assemblies with emphasis on thermo-mechanical as well as alignment stability verification.
NASA Astrophysics Data System (ADS)
Naresh, Sandrasekaran; Hoong Shuit, Siew; Kunasundari, Balakrishnan; Hoo Peng, Yong; Qi, Hwa Ng; Teoh, Yi Peng
2018-03-01
Bacillus subtilis UniMAP-KB01, a cellulase producer was isolated from Malaysian mangrove soil. Through morphological identification it was observed that the B. subtilis appears to be in rod shaped and identified as a gram positive bacterium. Growth profile of isolated B. subtilis was established by measuring optical density (OD) at 600 nm for every 1 hour intervals. Polymath software was employed to plot the growth profile and the non-linear plot established gave the precision value of linear regression, R2 of 0.9602, root mean square deviation (RMSD) of 0.0176 and variance of 0.0025. The hydrolysis capacity testing revealed the cellulolytic index of 2.83 ± 0.46 after stained with Gram’s Iodine. The harvested crude enzyme after 24 hours incubation in carboxymethylcellulose (CMC) broth at 45°C and 100 RPM, was tested for enzyme activity. Through Filter Paper Assay (FPA), the cellulase activity was calculated to be 0.05 U/mL. The hydrolysis capacity testing and FPA shown an acceptable value for thermophilic bacterial enzyme activity. Thus, this isolated strain reasoned to be potential for producing thermostable cellulase which will be immobilized onto multi-walled carbon nanotubes and the cellulolytic activity will be characterized for biofuel production.
Carrier Plus: A sensor payload for Living With a Star Space Environment Testbed (LWS/SET)
NASA Technical Reports Server (NTRS)
Marshall, Cheryl J.; Moss, Steven; Howard, Regan; LaBel, Kenneth A.; Grycewicz, Tom; Barth, Janet L.; Brewer, Dana
2003-01-01
The Defense Threat Reduction Agency (DTR4) and National Aeronautics and Space Administration (NASA) Goddard Space Flight Center are collaborating to develop the Carrier Plus sensor experiment platform as a capability of the Space Environments Testbed (SET). The Space Environment Testbed (SET) provides flight opportunities for technology experiments as part of NASA's Living With a Star (LWS) program. The Carrier Plus will provide new capability to characterize sensor technologies such as state-of-the-art visible focal plane arrays (FPAs) in a natural space radiation environment. The technical objectives include on-orbit validation of recently developed FPA technologies and performance prediction methodologies, as well as characterization of the FPA radiation response to total ionizing dose damage, displacement damage and transients. It is expected that the sensor experiment will carry 4-6 FPAs and associated radiation correlative environment monitors (CEMs) for a 2006-2007 launch. Sensor technology candidates may include n- and p-charge coupled devices (CCDs), active pixel sensors (APS), and hybrid CMOS arrays. The presentation will describe the Carrier Plus goals and objectives, as well as provide details about the architecture and design. More information on the LWS program can be found at http://lws.gsfc.nasa.gov/. Business announcements for LWS/SET and program briefings are posted at http://lws-set.gsfc.nasa.gov
Costigan, M G; Gilchrist, T L; Lindup, W E
1996-06-01
The furan dicarboxylic acid, 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid (5-propyl FPA) accumulates in the plasma of patients with chronic renal failure and is a major contributor to the drug binding defect of uraemic plasma. This acid has also been implicated in several other aspects of the uraemic syndrome: anaemia, irregularities of thyroid function, neurological symptoms and inhibition of active tubular secretion. The acid is not commercially available and its synthesis, starting with Meldrum's acid and methyl succinyl chloride, is described. The pKa values were measured by titration and values of 3.2 and 3.6 respectively were assigned to the carboxylic acid groups attached directly to the ring at position 3 and at position 2 (on the side-chain). The partition coefficient (log P) between hydrochloric acid and octanol was 1.2 and the distribution coefficient (log D; octanol-phosphate buffer pH 7.4) was -0.59. The pKa values and the degree of hydrophobic character of 5-propyl FPA are consistent with those of other protein-bound acids which undergo active tubular secretion by the kidney and this substance may serve as an endogenous marker for the effects of drugs and disease on this process.
Li, Yue; Zhang, Lei; Long, Kehong; Gong, Hui; Lei, Hao
2018-02-16
A growing body of literature has suggested that video game playing can induce functional and structural plasticity of the brain. The underlying mechanisms, however, remain poorly understood. In this study, functional near-infrared spectroscopy (fNIRS) was used to record prefrontal activities in 24 experienced game players when they played a massively multiplayer online battle arena video game, League of Legends (LOL), under naturalistic conditions. It was observed that game onset was associated with significant activations in the ventrolateral prefrontal cortex (VLPFC) and concomitant deactivations in the dorsolateral prefrontal cortex (DLPFC) and frontal pole area (FPA). Game events, such as slaying an enemy and being slain by an enemy evoked region-specific time-locked hemodynamic/oxygenation responses in the prefrontal cortex (PFC). It was proposed that the VLPFC activities during LOL playing are likely responses to visuo-motor task load of the game, while the DLPFC/FPA activities may be involved in the constant shifts of attentional states and allocation of cognitive resources required by game playing. The present study demonstrated that it is feasible to use fNIRS to monitor real-time prefrontal activity during online video game playing. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Thermoelectric infrared imager and automotive applications
NASA Astrophysics Data System (ADS)
Hirota, Masaki; Satou, Fuminori; Saito, Masanori; Kishi, Youichi; Nakajima, Yasushi; Uchiyama, Makato
2001-10-01
This paper describes a newly developed thermoelectric infrared imager having a 48 X 32 element thermoelectric focal plane array (FPA) and an experimental vehicle featuring a blind spot pedestrian warning system, which employs four infrared imagers. The imager measures 100 mm in width, 60 mm in height and 80 mm in depth, weighs 400 g, and has an overall field of view (FOV) of 40 deg X 20 deg. The power consumption of the imager is 3 W. The pedestrian detection program is stored in a CPU chip on a printed circuit board (PCB). The FPA provides high responsivity of 2,100 V/W, a time constant of 25 msec, and a low cost potential. Each element has external dimensions of 190 μm x 190 μm, and consists of six pairs of thermocouples and an Au-black absorber that is precisely patterned by low-pressure evaporation and lift-off technologies. The experimental vehicle is called the Nissan ASV-2 (Advanced Safety Vehicle-2), which incorporates a wide range of integrated technologies aimed at reducing traffic accidents. The blind spot pedestrian warning system alerts the driver to the presence of a pedestrian in a blind spot by detecting the infrared radiation emitted from the person's body. This system also prevents the vehicle from moving in the direction of the pedestrian.
NASA Astrophysics Data System (ADS)
Druart, Guillaume; Rommeluere, Sylvain; Viale, Thibault; Guerineau, Nicolas; Ribet-Mohamed, Isabelle; Crastes, Arnaud; Durand, Alain; Taboury, Jean
2014-05-01
Today, both military and civilian applications require miniaturized and cheap optical systems. One way to achieve this trend consists in decreasing the pixel pitch of focal plane arrays (FPA). In order to evaluate the performance of the overall optical systems, it is necessary to measure the modulation transfer function (MTF) of these pixels. However, small pixels lead to higher cut-off frequencies and therefore, original MTF measurements that are able to extract frequencies up to these high cut-off frequencies, are needed. In this paper, we will present a way to extract 1D MTF at high frequencies by projecting fringes on the FPA. The device uses a Lloyd mirror placed near and perpendicular to the focal plane array. Consequently, an interference pattern of fringes can be projected on the detector. By varying the angle of incidence of the light beam, we can tune the period of the interference fringes and, thus, explore a wide range of spatial frequencies, and mainly around the cut-off frequency of the pixel which is one of the most interesting area. Illustration of this method will be applied to a 640×480 microbolometer focal plane array with a pixel pitch of 17µm in the LWIR spectral region.
MBE HgCdTe for HDVIP Devices: Horizontal Integration in the US HgCdTe FPA Industry
NASA Astrophysics Data System (ADS)
Aqariden, F.; Elsworth, J.; Zhao, J.; Grein, C. H.; Sivananthan, S.
2012-10-01
Molecular beam epitaxy (MBE) growth of HgCdTe offers the possibility of fabricating multilayer device structures with an almost unlimited choice of infrared sensor designs for focal-plane array (FPA) fabrication. HgCdTe offers two major advantages that explain its dominance in the infrared photon detector marketplace. The thermal generation rate per unit volume of the material is lower and the quantum efficiency for photon absorption in the infrared is higher in HgCdTe than in any competing material—it yields devices with quantum efficiencies as high as 0.99. Recently, EPIR Technologies and DRS Infrared Technologies agreed to collaborate and examine: (i) the feasibility of employing MBE HgCdTe in the fabrication of high-density vertically interconnected photodiodes (HDVIPs), which are usually fabricated with liquid-phase epitaxy material, and (ii) the potential benefits of horizontal integration, with EPIR supplying the MBE materials to DRS for device and array fabrication. The team designed and developed passivation-absorber-passivation structures that are heavily used by DRS. This paper provides an overview of the characteristics of HDVIP devices and arrays fabricated from MBE HgCdTe and the anticipated advantages of horizontal integration in the industry. Material growth, device fabrication, and test results are presented.
Phonon renormalization and anharmonicity in Al-doped MgB2
NASA Astrophysics Data System (ADS)
Ortiz, Filiberto; Aguayo, Aarón
2005-03-01
We have studied the evolution of the E2g phonon mode dynamics in Mg1-xAlxB2 as a function of doping using the Frozen Phonon Approximation (FPA). The doping was modeled in the ab-initio Virtual Crystal Approximation (VCA). The results were obtained by means of first-principles total-energy calculations using the full potential Linearized Augmented Plane Wave (LAPW) method and the Generalized Gradient Approximation (GGA) for the exchange-correlation potential. We present results for the evolution of the phonon frequency and anharmonicity of the E2g mode as a function of Al concentration (x). From a comparison of the experimental data with the calculated E2g phonon frequency we show that the VCA-FPA reproduces the observed phonon renormalization in the whole range of Al concentrations. More interestingly, we find that the anharmonicity gradually decreases with Al doping and vanishes for x(Al)>0.5, that behaviour correlates with the evolution of the measured Raman linewidth in Al-doped MgB2. The significance of these results are discussed in the light of the experimentally observed loss of superconductivity in Mg1- xAlxB2.This work was supported by Consejo Nacional de Ciencia y Tecnolog'ia (CONACYT, M'exico) under Grant. No. 43830-F.
Common source cascode amplifiers for integrating IR-FPA applications
NASA Technical Reports Server (NTRS)
Woolaway, James T.; Young, Erick T.
1989-01-01
Space based astronomical infrared measurements present stringent performance requirements on the infrared detector arrays and their associated readout circuitry. To evaluate the usefulness of commercial CMOS technology for astronomical readout applications a theoretical and experimental evaluation was performed on source follower and common-source cascode integrating amplifiers. Theoretical analysis indicates that for conditions where the input amplifier integration capacitance is limited by the detectors capacitance the input referred rms noise electrons of each amplifier should be equivalent. For conditions of input gate limited capacitance the source follower should provide lower noise. Measurements of test circuits containing both source follower and common source cascode circuits showed substantially lower input referred noise for the common-source cascode input circuits. Noise measurements yielded 4.8 input referred rms noise electrons for an 8.5 minute integration. The signal and noise gain of the common-source cascode amplifier appears to offer substantial advantages in acheiving predicted noise levels.
Meiotic aneuploidy: its origins and induction following chemical treatment in Sordaria brevicollis.
Bond, D J; McMillan, L
1979-08-01
A system suitable for the detection of meiotic aneuploidy is described in which various different origins of the aneuploidy can be distinguished. Aneuploid meiotic products are detected as black disomic spores held in asci containing all the products of a single meiosis. Aneuploidy may result from nondisjunction or from a meiosis in which an extra replica of one of the chromosomes has been generated in some other way, e.g., extra replication. By using this system it has been shown that pFPA treatment increase aneuploidy, primarily through an effect on nondisjunction. Preliminary results with trifluralin have indicated that this compound, too, may increase aneuploidy. There is a good possibility that the system can be further developed to permit a more rapid screening using a random plating method; this will allow a more efficient two-part analysis of the effects of compounds under test.
Operational Ocean Modelling with the Harvard Ocean Prediction System
2008-11-01
tno.nl TNO-rapportnummer TNO-DV2008 A417 Opdrachtnummer Datum november 2008 Auteur (s) dr. F.P.A. Lam dr. ir. M.W. Schouten dr. L.A. te Raa...area of theory and implementation of numerical schemes and parameterizations, ocean models have grown from experimental tools to full-blown ocean...sound propagation through mesoscale features using 3-D coupled mode theory , Thesis, Naval Postgraduate School, Monterey, USA. 1992. [9] Robinson
Helmet-mounted uncooled FPA camera for use in firefighting applications
NASA Astrophysics Data System (ADS)
Wu, Cheng; Feng, Shengrong; Li, Kai; Pan, Shunchen; Su, Junhong; Jin, Weiqi
2000-05-01
From the concept and need background of firefighters to the thermal imager, we discuss how the helmet-mounted camera applied in the bad environment of conflagration, especially at the high temperature, and how the better matching between the thermal imager with the helmet will be put into effect in weight, size, etc. Finally, give a practical helmet- mounted IR camera based on the uncooled focal plane array detector for in firefighting.
Optical Jitter Effects on Target Detection and Tracking of Overhead Persistent Infrared Systems
2015-12-01
infrared CdSe cadmium selenide DSP Defense Support Program FIR far-infrared FPA focal plane array Ge germanium GEO geostationary earth orbit...HBCRT High Energy Laser Beam Control Research Testbed HEL high energy laser HgCdTe mercury cadmium telluride IR infrared InSb indium antimonide...MOD model MTF modulation transfer function MWIR mid-wave infrared NIR near infrared OPIR overhead persistent infrared PbSe lead selenide
The Focal Plane Assembly for the Athena X-Ray Integral Field Unit Instrument
NASA Technical Reports Server (NTRS)
Jackson, B. D.; Van Weers, H.; van der Kuur, J.; den Hartog, R.; Akamatsu, H.; Argan, A.; Bandler, S. R.; Barbera, M.; Barret, D.; Bruijn, M. P.;
2016-01-01
This paper summarizes a preliminary design concept for the focal plane assembly of the X-ray Integral Field Unit on the Athena spacecraft, an imaging microcalorimeter that will enable high spectral resolution imaging and point-source spectroscopy. The instrument's sensor array will be a 3840-pixel transition edge sensor (TES) microcalorimeter array, with a frequency domain multiplexed SQUID readout system allowing this large-format sensor array to be operated within the thermal constraints of the instrument's cryogenic system. A second TES detector will be operated in close proximity to the sensor array to detect cosmic rays and secondary particles passing through the sensor array for off-line coincidence detection to identify and reject events caused by the in-orbit high-energy particle background. The detectors, operating at 55 mK, or less, will be thermally isolated from the instrument cryostat's 2 K stage, while shielding and filtering within the FPA will allow the instrument's sensitive sensor array to be operated in the expected environment during both on-ground testing and in-flight operation, including stray light from the cryostat environment, low-energy photons entering through the X-ray aperture, low-frequency magnetic fields, and high-frequency electric fields.
Nossel, H. L.; Wasser, J.; Kaplan, K. L.; Lagamma, K. S.; Yudelman, I.; Canfield, R. E.
1979-01-01
Plasma fibrinopeptide B (Bβ1-14 or FPB) immunoreactivity was studied by radioimmunoassay in patients who received intrauterine infusion of hypertonic saline to terminate pregnancy. FPB immunoreactivity increased with thrombin treatment (TIFPB) suggesting the presence of a larger FPB-containing peptide, since purified FPB is not altered by thrombin, whereas thrombin increases the immunoreactivity of Bβ1-42 (which includes FPB) 10-fold. TIFPB immunoreactivity in plasma, drawn 4 h after hypertonic saline infusion eluted from Sephadex G-50 similarly to isolated Bβ1-42. Streptokinase, incubated with normal plasma progressively generated TIFPB immunoreactivity, which showed a major component which eluted from Sephadex G-50 similarly to Bβ1-42. Streptokinase generated TIFPB much more rapidly in reptilase-treated plasma that contains fibrin I, (which still includes FPB), indicating that fibrin I is preferred over fibrinogen as a substrate for plasmin cleavage of arginine (Bβ42)-alanine (Bβ43). Serial studies were then made in 10 patients receiving intrauterine hypertonic saline. Fibrinopeptide A (FPA) levels rose immediately, reached a peak between 1 and 2 h, were declining at 4 h, and were normal at 24 and 48 h. TIFPB levels rose slightly in the 1st h, reached a peak at 4 h, and had returned to base-line values at 24 h. Serum fibrinogen degradation product levels were unchanged at 1 h, reached their highest level at 4 h, and were still markedly elevated at 24 and 48 h. Fibrinogen levels dropped slightly being lowest at 4 and 24 h. Platelet counts declined in parallel with the fibrinogen levels over the first 4 h, but continued to decrease through 48 h. Beta thromboglobulin (βTG) levels generally paralleled FPA levels whereas platelet factor 4 (PF4) levels showed only slight changes. The data indicate that immediately after intrauterine hypertonic saline infusion thrombin is formed that cleaves FPA from fibrinogen to produce fibrin I and releases βTG and PF4 from platelets. Later plasmin cleaves Bβ1-42 from fibrin I to produce fragment X, which is further degraded to form serum fibrinogen degradation products. This sequence of proteolysis indicates that plasmin action on fibrin I serves as a mechanism that regulates fibrin II formation by removing the Bβ chain cleavage site, which is required for thrombin action in converting fibrin I to fibrin II. PMID:500818
NASA Astrophysics Data System (ADS)
Bartlett, Marcus A.; Liang, Tao; Pu, Liang; Schaefer, Henry F.; Allen, Wesley D.
2018-03-01
The n-propyl + O2 reaction is an important model of chain branching reactions in larger combustion systems. In this work, focal point analyses (FPAs) extrapolating to the ab initio limit were performed on the n-propyl + O2 system based on explicit quantum chemical computations with electron correlation treatments through coupled cluster single, double, triple, and perturbative quadruple excitations [CCSDT(Q)] and basis sets up to cc-pV5Z. All reaction species and transition states were fully optimized at the rigorous CCSD(T)/cc-pVTZ level of theory, revealing some substantial differences in comparison to the density functional theory geometries existing in the literature. A mixed Hessian methodology was implemented and benchmarked that essentially makes the computations of CCSD(T)/cc-pVTZ vibrational frequencies feasible and thus provides critical improvements to zero-point vibrational energies for the n-propyl + O2 system. Two key stationary points, n-propylperoxy radical (MIN1) and its concerted elimination transition state (TS1), were located 32.7 kcal mol-1 and 2.4 kcal mol-1 below the reactants, respectively. Two competitive β-hydrogen transfer transition states (TS2 and TS2') were found separated by only 0.16 kcal mol-1, a fact unrecognized in the current combustion literature. Incorporating TS2' in master equation (ME) kinetic models might reduce the large discrepancy of 2.5 kcal mol-1 between FPA and ME barrier heights for TS2. TS2 exhibits an anomalously large diagonal Born-Oppenheimer correction (ΔDBOC = 1.71 kcal mol-1), which is indicative of a nearby surface crossing and possible nonadiabatic reaction dynamics. The first systematic conformational search of three hydroperoxypropyl (QOOH) intermediates was completed, uncovering a total of 32 rotamers lying within 1.6 kcal mol-1 of their respective lowest-energy minima. Our definitive energetics for stationary points on the n-propyl + O2 potential energy surface provide key benchmarks for future studies of hydrocarbon oxidation.
Evaluation of vertical profiles to design continuous descent approach procedure
NASA Astrophysics Data System (ADS)
Pradeep, Priyank
The current research focuses on predictability, variability and operational feasibility aspect of Continuous Descent Approach (CDA), which is among the key concepts of the Next Generation Air Transportation System (NextGen). The idle-thrust CDA is a fuel economical, noise and emission abatement procedure, but requires increased separation to accommodate for variability and uncertainties in vertical and speed profiles of arriving aircraft. Although a considerable amount of researches have been devoted to the estimation of potential benefits of the CDA, only few have attempted to explain the predictability, variability and operational feasibility aspect of CDA. The analytical equations derived using flight dynamics and Base of Aircraft and Data (BADA) Total Energy Model (TEM) in this research gives insight into dependency of vertical profile of CDA on various factors like wind speed and gradient, weight, aircraft type and configuration, thrust settings, atmospheric factors (deviation from ISA (DISA), pressure and density of the air) and descent speed profile. Application of the derived equations to idle-thrust CDA gives an insight into sensitivity of its vertical profile to multiple factors. This suggests fixed geometric flight path angle (FPA) CDA has higher degree of predictability and lesser variability at the cost of non-idle and low thrust engine settings. However, with optimized design this impact can be overall minimized. The CDA simulations were performed using Future ATM Concept Evaluation Tool (FACET) based on radar-track and aircraft type data (BADA) of the real air-traffic to some of the busiest airports in the USA (ATL, SFO and New York Metroplex (JFK, EWR and LGA)). The statistical analysis of the vertical profiles of CDA shows 1) mean geometric FPAs derived from various simulated vertical profiles are consistently shallower than 3° glideslope angle and 2) high level of variability in vertical profiles of idle-thrust CDA even in absence of uncertainties in external factors. Analysis from operational feasibility perspective suggests that two key features of the performance based Flight Management System (FMS) i.e. required time of arrival (RTA) and geometric descent path would help in reduction of unpredictability associated with arrival time and vertical profile of aircraft guided by the FMS coupled with auto-pilot (AP) and auto-throttle (AT). The statistical analysis of the vertical profiles of CDA also suggests that for procedure design window type, 'AT or above' and 'AT or below' altitude and FPA constraints are more realistic and useful compared to obsolete 'AT' type altitude constraint.
A 3.5 to 12 Micron Dualband Spectrometer for Generic UAVs
2005-05-01
AUTHOR( S ) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) Air Force Research Laboratory...AGENCY NAME( S ) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM( S ) 11. SPONSOR/MONITOR’S REPORT NUMBER( S ) 12. DISTRIBUTION/AVAILABILITY STATEMENT...implementation. REFERENCES [1] T. D. Maestas & P.D. LeVan (2002). Novel, Three-Octave, Infrared Hyperspectral Imaging with a Single Multi-waveband FPA
Thermal performance testing of two Thales 9310 pulse-tube cryocoolers for PHyTIR
DOE Office of Scientific and Technical Information (OSTI.GOV)
Paine, Christopher G.
2014-01-29
PHyTIR is a NASA-funded technology demonstration for a near-term earth-observing instrument in the thermal infrared spectrum, intended for use in the HyspIRI mission. PHyTIR will use two Thales 9310 single-stage pulse tube cryocoolers, one to directly cool the FPA, the other to simulate a passive radiator. We report performance measurements for the two Thales 9310 cryocoolers intended for inclusion in the PHyTIR demonstrator.
QWIP and third-generation IR imagers
NASA Astrophysics Data System (ADS)
Costard, E.; Bois, Ph.; Marcadet, X.; Nedelcu, A.
2005-10-01
Standard GaAs/AlGaAs Quantum Well Infrared Photodetectors (QWIP) are from now seriously considered for the 3rd generation of IR imagers for military markets. Since 2002, the THALES Group has been manufacturing sensitive arrays using QWIP technology based on AsGa techniques through THALES Research and Technology Laboratory. This QWIP technology allows the realization of large staring arrays for Thermal Imagers (TI) working in the IR band III (8-12 μm). A review of the current QWIP products is presented. In the past researchers claimed many advantages of QWIPs. Uniformity was one of these and is the key parameter for the production start. By presenting our first results of a 640x512 LWIR FPA at a pitch of 20μm we also demonstrate that very high performances can be achieved even with small pixels which opens the field for the realization of usable and affordable megapixel FPAs. Another advantage widely claimed in the past for QWIPs was the so-called band-gap engineering and versatility of the III-V processing allowing the custom design of quantum structure to fulfill the requirements of specific applications like very long wavelength (VLWIR) or multispectral detection. In this presentation, we present the performances of our first 256x256 MWIR / LWIR two color FPA at a pitch of 25 μm, and also the current status of QWIPs for VLWIR arrays (>15μm).
Improved calibration-based non-uniformity correction method for uncooled infrared camera
NASA Astrophysics Data System (ADS)
Liu, Chengwei; Sui, Xiubao
2017-08-01
With the latest improvements of microbolometer focal plane arrays (FPA), uncooled infrared (IR) cameras are becoming the most widely used devices in thermography, especially in handheld devices. However the influences derived from changing ambient condition and the non-uniform response of the sensors make it more difficult to correct the nonuniformity of uncooled infrared camera. In this paper, based on the infrared radiation characteristic in the TEC-less uncooled infrared camera, a novel model was proposed for calibration-based non-uniformity correction (NUC). In this model, we introduce the FPA temperature, together with the responses of microbolometer under different ambient temperature to calculate the correction parameters. Based on the proposed model, we can work out the correction parameters with the calibration measurements under controlled ambient condition and uniform blackbody. All correction parameters can be determined after the calibration process and then be used to correct the non-uniformity of the infrared camera in real time. This paper presents the detail of the compensation procedure and the performance of the proposed calibration-based non-uniformity correction method. And our method was evaluated on realistic IR images obtained by a 384x288 pixels uncooled long wave infrared (LWIR) camera operated under changed ambient condition. The results show that our method can exclude the influence caused by the changed ambient condition, and ensure that the infrared camera has a stable performance.
High-frame-rate infrared and visible cameras for test range instrumentation
NASA Astrophysics Data System (ADS)
Ambrose, Joseph G.; King, B.; Tower, John R.; Hughes, Gary W.; Levine, Peter A.; Villani, Thomas S.; Esposito, Benjamin J.; Davis, Timothy J.; O'Mara, K.; Sjursen, W.; McCaffrey, Nathaniel J.; Pantuso, Francis P.
1995-09-01
Field deployable, high frame rate camera systems have been developed to support the test and evaluation activities at the White Sands Missile Range. The infrared cameras employ a 640 by 480 format PtSi focal plane array (FPA). The visible cameras employ a 1024 by 1024 format backside illuminated CCD. The monolithic, MOS architecture of the PtSi FPA supports commandable frame rate, frame size, and integration time. The infrared cameras provide 3 - 5 micron thermal imaging in selectable modes from 30 Hz frame rate, 640 by 480 frame size, 33 ms integration time to 300 Hz frame rate, 133 by 142 frame size, 1 ms integration time. The infrared cameras employ a 500 mm, f/1.7 lens. Video outputs are 12-bit digital video and RS170 analog video with histogram-based contrast enhancement. The 1024 by 1024 format CCD has a 32-port, split-frame transfer architecture. The visible cameras exploit this architecture to provide selectable modes from 30 Hz frame rate, 1024 by 1024 frame size, 32 ms integration time to 300 Hz frame rate, 1024 by 1024 frame size (with 2:1 vertical binning), 0.5 ms integration time. The visible cameras employ a 500 mm, f/4 lens, with integration time controlled by an electro-optical shutter. Video outputs are RS170 analog video (512 by 480 pixels), and 12-bit digital video.
Strongly Coupled Models with a Higgs-like Boson
NASA Astrophysics Data System (ADS)
Pich, Antonio; Rosell, Ignasi; José Sanz-Cillero, Juan
2013-11-01
Considering the one-loop calculation of the oblique S and T parameters, we have presented a study of the viability of strongly-coupled scenarios of electroweak symmetry breaking with a light Higgs-like boson. The calculation has been done by using an effective Lagrangian, being short-distance constraints and dispersive relations the main ingredients of the estimation. Contrary to a widely spread believe, we have demonstrated that strongly coupled electroweak models with massive resonances are not in conflict with experimentalconstraints on these parameters and the recently observed Higgs-like resonance. So there is room for these models, but they are stringently constrained. The vector and axial-vector states should be heavy enough (with masses above the TeV scale), the mass splitting between them is highly preferred to be small and the Higgs-like scalar should have a WW coupling close to the Standard Model one. It is important to stress that these conclusions do not depend critically on the inclusion of the second Weinberg sum rule. We wish to thank the organizers of LHCP 2013 for the pleasant conference. This work has been supported in part by the Spanish Government and the European Commission [FPA2010-17747, FPA2011- 23778, AIC-D-2011-0818, SEV-2012-0249 (Severo Ochoa Program), CSD2007-00042 (Consolider Project CPAN)], the Generalitat Valenciana [PrometeoII/2013/007] and the Comunidad de Madrid [HEPHACOS S2009/ESP-1473].
Studies of jet cross-sections and production properties with the ATLAS and CMS detectors
NASA Astrophysics Data System (ADS)
Anjos, Nuno
2016-07-01
Several characteristics of jet production in pp collisions have been measured by the ATLAS and CMS collaborations at the LHC. Measurements of event shapes and multi-jet production probe the dynamics of QCD in the soft regime and can constrain parton shower and hadronisation models. Measurements of multi-jet systems with a veto on additional jets probe QCD radiation effects. Double-differential cross-sections for threeand four-jet final states are measured at different centre-of-mass energies of pp collisions and are compared to expectations based on NLO QCD calculations. The distribution of the jet charge has been measured in di-jet events and compared to predictions from different hadronisation models and tunes. Jet-jet energy correlations are sensitive to the strong coupling constant. These measurements constitute precision tests of QCD in a new energy regime. Work supported by the Beatriu de Pinós program managed by Agència de Gestió d'Ajuts Universitaris i de Recerca with the support of the Secretaria d'Universitats i Recerca of the Departament d'Economia i Coneixement of the Generalitat de Catalunya, and the Cofund program of the Marie Curie Actions of the 7th R&D Framework Program of the European Union. Work partially supported by MINECO under grants SEV-2012-0234, FPA2013-48308, and FPA2012-38713, which include FEDER funds from the European Union.
Studies of DNA supercoiling in vivo and in vitro
DOE Office of Scientific and Technical Information (OSTI.GOV)
Cook, David Nelson
This thesis describes a number of diverse experiments whose common theme is to elaborate some aspect of DNA supercoiling. The torsion elastic constant of DNA is measure as a function of superhelix density using the technique of picosecond Time Resolved Fluorescence Polarization Anisotropy (FPA) of intercalated ethidium bromide. The results agree with theories which predict that the anisotropy decay should vary with the square root of the relative viscosity. This experiment furthermore demonstrates a sensitivity of FPA to a change in torsion elastic constant of less than 10%. A number of covalently closed DNA samples, ranging in superhelix density frommore » = -0.123 to +0.042, are then examined. A novel method for measuring changes in local supercoiling on a large PNA molecule which is sensitive to changes in supercoiling of regions of chromosomal DNA as short as 1 kilobase in length is presented. Study of chromosomal supercoiling regulating anaerobic gene expression in the facultative photosynthetic bacterium, Rhodobacter capsulatus showed that no stable change in chromosomal supercoiling upon a shift from aerobic respiratory growth to anaerobic photosynthetic conditions. Studies to detect transient changes in DNA supercoiling indicate that DNA downstream from heavily transcribed genes for the photosynthetic reaction center are relaxed or perhaps overwound upon the induction of photosynthetic metabolism. These results are interpreted in terms of the twin domain model of transcriptional supercoiling.« less
Studies of DNA supercoiling in vivo and in vitro
DOE Office of Scientific and Technical Information (OSTI.GOV)
Cook, D.N.
This thesis describes a number of diverse experiments whose common theme is to elaborate some aspect of DNA supercoiling. The torsion elastic constant of DNA is measure as a function of superhelix density using the technique of picosecond Time Resolved Fluorescence Polarization Anisotropy (FPA) of intercalated ethidium bromide. The results agree with theories which predict that the anisotropy decay should vary with the square root of the relative viscosity. This experiment furthermore demonstrates a sensitivity of FPA to a change in torsion elastic constant of less than 10%. A number of covalently closed DNA samples, ranging in superhelix density frommore » = [minus]0.123 to [plus]0.042, are then examined. A novel method for measuring changes in local supercoiling on a large PNA molecule which is sensitive to changes in supercoiling of regions of chromosomal DNA as short as 1 kilobase in length is presented. Study of chromosomal supercoiling regulating anaerobic gene expression in the facultative photosynthetic bacterium, Rhodobacter capsulatus showed that no stable change in chromosomal supercoiling upon a shift from aerobic respiratory growth to anaerobic photosynthetic conditions. Studies to detect transient changes in DNA supercoiling indicate that DNA downstream from heavily transcribed genes for the photosynthetic reaction center are relaxed or perhaps overwound upon the induction of photosynthetic metabolism. These results are interpreted in terms of the twin domain model of transcriptional supercoiling.« less
Development of a 1K x 1K GaAs QWIP Far IR Imaging Array
NASA Technical Reports Server (NTRS)
Jhabvala, M.; Choi, K.; Goldberg, A.; La, A.; Gunapala, S.
2003-01-01
In the on-going evolution of GaAs Quantum Well Infrared Photodetectors (QWIPs) we have developed a 1,024 x 1,024 (1K x1K), 8.4-9 microns infrared focal plane array (FPA). This 1 megapixel detector array is a hybrid using the Rockwell TCM 8050 silicon readout integrated circuit (ROIC) bump bonded to a GaAs QWIP array fabricated jointly by engineers at the Goddard Space Flight Center (GSFC) and the Army Research Laboratory (ARL). The finished hybrid is thinned at the Jet Propulsion Lab. Prior to this development the largest format array was a 512 x 640 FPA. We have integrated the 1K x 1K array into an imaging camera system and performed tests over the 40K-90K temperature range achieving BLIP performance at an operating temperature of 76K (f/2 camera system). The GaAs array is relatively easy to fabricate once the superlattice structure of the quantum wells has been defined and grown. The overall arrays costs are currently dominated by the costs associated with the silicon readout since the GaAs array fabrication is based on high yield, well-established GaAs processing capabilities. In this paper we will present the first results of our 1K x 1K QWIP array development including fabrication methodology, test data and our imaging results.
NASA Astrophysics Data System (ADS)
Chatterjee, Abhijit; Verma, Anurag
2016-05-01
The Advanced Wide Field Sensor (AWiFS) camera caters to high temporal resolution requirement of Resourcesat-2A mission with repeativity of 5 days. The AWiFS camera consists of four spectral bands, three in the visible and near IR and one in the short wave infrared. The imaging concept in VNIR bands is based on push broom scanning that uses linear array silicon charge coupled device (CCD) based Focal Plane Array (FPA). On-Board Calibration unit for these CCD based FPAs is used to monitor any degradation in FPA during entire mission life. Four LEDs are operated in constant current mode and 16 different light intensity levels are generated by electronically changing exposure of CCD throughout the calibration cycle. This paper describes experimental setup and characterization results of various flight model visible LEDs (λP=650nm) for development of On-Board Calibration unit of Advanced Wide Field Sensor (AWiFS) camera of RESOURCESAT-2A. Various LED configurations have been studied to meet dynamic range coverage of 6000 pixels silicon CCD based focal plane array from 20% to 60% of saturation during night pass of the satellite to identify degradation of detector elements. The paper also explains comparison of simulation and experimental results of CCD output profile at different LED combinations in constant current mode.
NASA Technical Reports Server (NTRS)
Gallegos, Gregory L.; Hilaire, Emmanuel M.; Peterson, Barbara V.; Brown, Christopher S.; Guikema, James A.
1995-01-01
Starch filled plastids termed amyloplasts, contained within columella cells of the root caps of higher plant roots, are believed to play a statolith-like role in the gravitropic response of roots. Plants having amyloplasts containing less starch exhibit a corresponding reduction in gravitropic response. We have observed enhanced ethylene production by sweet clover (Melilotus alba L.) seedlings grown in the altered gravity condition of a slow rotating clinostat, and have suggested that this is a stress response resulting from continuous gravistimulation rather than as a result of the simulation of a microgravity condition. If so, we expect that plants deficient in starch accumulation in amyloplasts may produce less stress ethylene when grown on a clinostat. Therefore, we have grown Arabidopsis thaliana in the small, closed environment of the Fluid Processing Apparatus (FPA). In this preliminary report we compare stationary plants with clinorotated and those grown in microgravity aboard Discovery during the STS-63 flight in February 1995. In addition to wildtype, two mutants deficient in starch biosynthesis, mutants TC7 and TL25, which are, respectively, deficient in the activity of amyloplast phosphoglucomutase and ADP-glucose pyrophosphorylase, were grown for three days before being fixed within the FPA. Gas samples were aspirated from the growth chambers and carbon dioxide and ethylene concentations were measured using a gas chromatograph. The fixed tissue is currently undergoing further morphologic and microscopic characterization.
Multispectral Imager With Improved Filter Wheel and Optics
NASA Technical Reports Server (NTRS)
Bremer, James C.
2007-01-01
Figure 1 schematically depicts an improved multispectral imaging system of the type that utilizes a filter wheel that contains multiple discrete narrow-band-pass filters and that is rotated at a constant high speed to acquire images in rapid succession in the corresponding spectral bands. The improvement, relative to prior systems of this type, consists of the measures taken to prevent the exposure of a focal-plane array (FPA) of photodetectors to light in more than one spectral band at any given time and to prevent exposure of the array to any light during readout. In prior systems, these measures have included, variously the use of mechanical shutters or the incorporation of wide opaque sectors (equivalent to mechanical shutters) into filter wheels. These measures introduce substantial dead times into each operating cycle intervals during which image information cannot be collected and thus incoming light is wasted. In contrast, the present improved design does not involve shutters or wide opaque sectors, and it reduces dead times substantially. The improved multispectral imaging system is preceded by an afocal telescope and includes a filter wheel positioned so that its rotation brings each filter, in its turn, into the exit pupil of the telescope. The filter wheel contains an even number of narrow-band-pass filters separated by narrow, spoke-like opaque sectors. The geometric width of each filter exceeds the cross-sectional width of the light beam coming out of the telescope. The light transmitted by the sequence of narrow-band filters is incident on a dichroic beam splitter that reflects in a broad shorter-wavelength spectral band that contains half of the narrow bands and transmits in a broad longer-wavelength spectral band that contains the other half of the narrow spectral bands. The filters are arranged on the wheel so that if the pass band of a given filter is in the reflection band of the dichroic beam splitter, then the pass band of the adjacent filter is in the longer-wavelength transmission band of the dichroic beam splitter (see Figure 2). Each of the two optical paths downstream of the dichroic beam splitter contains an additional broad-band-pass filter: The filter in the path of the light transmitted by the dichroic beam splitter transmits and attenuates in the same bands that are transmitted and reflected, respectively, by the beam splitter; the filter in the path of the light reflected by the dichroic beam splitter transmits and attenuates in the same bands that are reflected and transmitted, respectively, by the dichroic beam splitter. In each of these paths, the filtered light is focused onto an FPA. As the filter wheel rotates at a constant angular speed, its shaft angle is monitored, and the shaft-angle signal is used to synchronize the exposure times of the two FPAs. When a single narrowband-pass filter on the wheel occupies the entire cross section of the beam of light coming out of the telescope, the spectrum of light that reaches the dichroic beam splitter lies entirely within the pass band of that filter. Therefore, the beam in its entirety is either transmitted by the dichroic beam splitter and imaged on the longer-wavelength FPA or reflected by the beam splitter and imaged onto the shorter-wavelength FPA.
Characterization of HgCdTe and HgCdSe Materials for Third Generation Infrared Detectors
2011-12-01
information if it does not display a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. Arizona State University ORSPA...UNIVERSITY December 2011 i ABSTRACT HgCdTe is the dominant material currently in use for infrared (IR) focal- plane-array (FPA) technology. In...using HgCdTe have since been made, and it currently represents the dominant material used in all IR spectral bands, primarily for space and
1992-01-01
tactical computers. The module must correct for optical irregularities in illumination, pixel gain, offset nonuniformities due to dark currents and...large search FOR, for IR FPA. DESCRIPTION: Large area staring IR lPAs in both Medium Wavelength Infrared (MWIR) and Long Wavelength Infrared ( LWIR ) are a...of HTS materials to BLIP limited detection of radiation in the optical, IR, MWIR, and LWIR bands as well as for signal processing applications is also
Future sensor system needs for staring arrays
NASA Astrophysics Data System (ADS)
Miller, John Lester
2011-05-01
This is a systems application paper regarding how sensor systems may use future technology FPAs. A historical perspective is discussed along with lessons learned from previous technologies. Future system requirements for strained super-lattice (SLS), quantum dots (QDOT) and traditional quantum well infrared photo-diodes (QWIP) arrays will be presented from both a commercial and military perspective. New potential markets will open up in the future if certain FPA technologies can reduce cost and provide higher sensitivities at higher operating temperatures.
2007-06-01
of SNR, she incorporated the effects that an InGaAs photovoltaic detector have in producing the signal along with the photon, Johnson, and shot noises ...the photovoltaic FPA detector modeled? • What detector noise sources limit the computed signal? 3.1 Modeling Methodology Two aspects in the IR camera...Another shot noise source in photovoltaic detectors is dark current. This current represents the current flowing in the detector when no optical radiation
3S2: Behavioral Response Studies of Cetaceans to Navy Sonar Signals in Norwegian Waters
2014-09-30
severity of behavioral changes observed during experimental exposures of killer (Orcinus orca), long-finned pilot (Globicephala melas ), and sperm...finned pilot whales (Globicephala melas ). Marine Mammal sci (DOI: 10.1111/mms.12099). Antunes R., Kvadsheim P.H., Lam F.P.A., Tyack, P.L., Thomas, L... melas ). Mar. Poll. Bull. (DOI: 10.1016/j.marpolbul.2014.03.056) Aoki K, Sakai M, Miller PJO, Visser F, Sato K (2013) Body contact and synchronous dives
2008-11-01
Datum Auteur (s) november 2008 dr. LA. teRaa dr. I.PA. Lam dr. ir. M.W. Schouten Rubricering rappon Vastgesteld door Vastgesteld d.d. I ltd...DenV@tno.nl TNO-rapportnummer TNO-DV2008A418 Opdrachtnummer Datum november 2008 Auteur (s) dr. L.A. te Raa dr. F.P.A. Lam dr. ir. M.W. Schouten...verdamping. Een oceaanmodel is gebaseerd op wiskundige vergelijkingen die de dynamica en thermodynamica van de oceaan beschrijven. In theorie geven deze
NS(B) (Nitrogen Sulfide (B State)) Spectrum Theory and Code
1989-05-01
8217TRAhS’oTRWCNp laP) ,NIfIP C NOTE: EP- BPP <C FCF RED DEGRADED BANDS C PP- BPP >C FCF BLUE DEGRACED eANCS WRITEC3o*) *BP-EPPs’f9(NN*1,I)-8CNNpIP) 60... FMA X. GT .Ft!ACLC .AND .C FPA X1 /FMAX ) GT..2) THEN XPEAK (N,IoIP)=XI1 YP EAK (N.,!,IP) rnPA)I( PE AX(N, IIP) ,FPAX) FfAX CLD=F PAX ENDIF 5
Dynamic full-field infrared imaging with multiple synchrotron beams
Stavitski, Eli; Smith, Randy J.; Bourassa, Megan W.; Acerbo, Alvin S.; Carr, G. L.; Miller, Lisa M.
2013-01-01
Microspectroscopic imaging in the infrared (IR) spectral region allows for the examination of spatially resolved chemical composition on the microscale. More than a decade ago, it was demonstrated that diffraction limited spatial resolution can be achieved when an apertured, single pixel IR microscope is coupled to the high brightness of a synchrotron light source. Nowadays, many IR microscopes are equipped with multi-pixel Focal Plane Array (FPA) detectors, which dramatically improve data acquisition times for imaging large areas. Recently, progress been made toward efficiently coupling synchrotron IR beamlines to multi-pixel detectors, but they utilize expensive and highly customized optical schemes. Here we demonstrate the development and application of a simple optical configuration that can be implemented on most existing synchrotron IR beamlines in order to achieve full-field IR imaging with diffraction-limited spatial resolution. Specifically, the synchrotron radiation fan is extracted from the bending magnet and split into four beams that are combined on the sample, allowing it to fill a large section of the FPA. With this optical configuration, we are able to oversample an image by more than a factor of two, even at the shortest wavelengths, making image restoration through deconvolution algorithms possible. High chemical sensitivity, rapid acquisition times, and superior signal-to-noise characteristics of the instrument are demonstrated. The unique characteristics of this setup enabled the real time study of heterogeneous chemical dynamics with diffraction-limited spatial resolution for the first time. PMID:23458231
MCT-Based LWIR and VLWIR 2D Focal Plane Detector Arrays for Low Dark Current Applications at AIM
NASA Astrophysics Data System (ADS)
Hanna, S.; Eich, D.; Mahlein, K.-M.; Fick, W.; Schirmacher, W.; Thöt, R.; Wendler, J.; Figgemeier, H.
2016-09-01
We present our latest results on n-on- p as well as on p-on- n low dark current planar mercury cadmium telluride (MCT) photodiode technology long wavelength infrared (LWIR) and very long wavelength infrared (VLWIR) two-dimensional focal plane arrays (FPAs) with quantum efficiency (QE) cut-off wavelength >11 μm at 80 K and a 512 × 640 pixel format FPA at 20 μm pitch stitched from two 512 × 320 pixel photodiode arrays. Significantly reduced dark currents as compared with Tennant's "Rule 07" are demonstrated in both polarities while retaining good detection efficiency ≥60% for operating temperatures between 30 K and 100 K. This allows for the same dark current performance at 20 K higher operating temperature than with previous AIM INFRAROT-MODULE GmbH (AIM) technology. For p-on- n LWIR MCT FPAs, broadband photoresponse nonuniformity of only about 1.2% is achieved at 55 K with low defective pixel numbers. For an n-on- p VLWIR MCT FPA with 13.6 μm cut-off at 55 K, excellent photoresponse nonuniformity of about 3.1% is achieved at moderate defective pixel numbers. This advancement in detector technology paves the way for outstanding signal-to-noise ratio performance infrared detection, enabling cutting-edge next-generation LWIR/VLWIR detectors for space instruments and devices with higher operating temperature and low size, weight, and power for field applications.
NASA Astrophysics Data System (ADS)
Cao, Yanpeng; Tisse, Christel-Loic
2013-06-01
In uncooled LWIR microbolometer imaging systems, temperature fluctuations of FPA (Focal Plane Array) as well as lens and mechanical components placed along the optical path result in thermal drift and spatial non-uniformity. These non-idealities generate undesirable FPN (Fixed-Pattern-Noise) that is difficult to remove using traditional, individual shutterless and TEC-less (Thermo-Electric Cooling) techniques. In this paper we introduce a novel single-image based processing approach that marries the benefits of both statistical scene-based and calibration-based NUC algorithms, without relying neither on extra temperature reference nor accurate motion estimation, to compensate the resulting temperature-dependent non-uniformities. Our method includes two subsequent image processing steps. Firstly, an empirical behavioral model is derived by calibrations to characterize the spatio-temporal response of the microbolometric FPA to environmental and scene temperature fluctuations. Secondly, we experimentally establish that the FPN component caused by the optics creates a spatio-temporally continuous, low frequency, low-magnitude variation of the image intensity. We propose to make use of this property and learn a prior on the spatial distribution of natural image gradients to infer the correction function for the entire image. The performance and robustness of the proposed temperature-adaptive NUC method are demonstrated by showing results obtained from a 640×512 pixels uncooled LWIR microbolometer imaging system operating over a broad range of temperature and with rapid environmental temperature changes (i.e. from -5°C to 65°C within 10 minutes).
Wide-band (2.5 - 10.5 µm), high-frame rate IRFPAs based on high-operability MCT on silicon
NASA Astrophysics Data System (ADS)
Crosbie, Michael J.; Giess, Jean; Gordon, Neil T.; Hall, David J.; Hails, Janet E.; Lees, David J.; Little, Christopher J.; Phillips, Tim S.
2010-04-01
We have previously presented results from our mercury cadmium telluride (MCT, Hg1-xCdxTe) growth on silicon substrate technology for different applications, including negative luminescence, long waveband and mid/long dual waveband infrared imaging. In this paper, we review recent developments in QinetiQ's combined molecular beam epitaxy (MBE) and metal-organic vapor phase epitaxy (MOVPE) MCT growth on silicon; including MCT defect density, uniformity and reproducibility. We also present a new small-format (128 x 128) focal plane array (FPA) for high frame-rate applications. A custom high-speed readout integrated circuit (ROIC) was developed with a large pitch and large charge storage aimed at producing a very high performance FPA (NETD ~10mK) operating at frame rates up to 2kHz for the full array. The array design allows random addressing and this allows the maximum frame rate to be increased as the window size is reduced. A broadband (2.5-10.5 μm) MCT heterostructure was designed and grown by the MBE/MOVPE technique onto silicon substrates. FPAs were fabricated using our standard techniques; wet-etched mesa diodes passivated with epitaxial CdTe and flip-chip bonded to the ROIC. The resulting focal plane arrays were characterized at the maximum frame rate and shown to have the high operabilities and low NETD values characteristic of our LWIR MCT on silicon technology.
NASA Astrophysics Data System (ADS)
Narong, L. C.; Sia, C. K.; Yee, S. K.; Ong, P.; Zainudin, A.; Nor, N. H. M.; Kasim, N. A.
2017-01-01
In order to solve the electromagnetic interference (EMI) issue and provide a new application for palm oil fuel ash (POFA), POFA was used as the cement filler for enhancing the EMI absorption of cement-based composites. POFA was refined by using water precipitation for 24 hours to remove the filthiness and distinguish the layer 1 (floated) and layer 2 (sink) of POFA. Both layers POFA were dried for 24 hours at 100 ± 5 °C and grind separately for sieve at 140 μm (Fine) and 45 цш sizes (Ultrafine). The micro structure and element content of the both layers POFA were characterized by scanning electron microscope (SEM) and energy-dispersive X-ray spectroscopy (EDS) respectively. The results showed layer 1 POFA has potentialities for EMI shielding effectiveness (SE) due to its higher carbon content and porous structure. The study reveals that EMI SE also influenced by the particle size of POFA, where smaller particle size can increase 5 % to 13 % of EMI SE. When the specimen consists of 50% POFA with passing through 45 μm sieve, the EMI was shield -13.08 dB in between 50 MHz to 2 GHz range. Flower Pollination Algorithm (FPA) proves that POFA passing 45 μm sieve with 50% mixed to OPC is optimal parameter. The error between experimental and FPA simulation data is below 1.2 for both layers POFA.
Fast, High-Precision Readout Circuit for Detector Arrays
NASA Technical Reports Server (NTRS)
Rider, David M.; Hancock, Bruce R.; Key, Richard W.; Cunningham, Thomas J.; Wrigley, Chris J.; Seshadri, Suresh; Sander, Stanley P.; Blavier, Jean-Francois L.
2013-01-01
The GEO-CAPE mission described in NASA's Earth Science and Applications Decadal Survey requires high spatial, temporal, and spectral resolution measurements to monitor and characterize the rapidly changing chemistry of the troposphere over North and South Americas. High-frame-rate focal plane arrays (FPAs) with many pixels are needed to enable such measurements. A high-throughput digital detector readout integrated circuit (ROIC) that meets the GEO-CAPE FPA needs has been developed, fabricated, and tested. The ROIC is based on an innovative charge integrating, fast, high-precision analog-to-digital circuit that is built into each pixel. The 128×128-pixel ROIC digitizes all 16,384 pixels simultaneously at frame rates up to 16 kHz to provide a completely digital output on a single integrated circuit at an unprecedented rate of 262 million pixels per second. The approach eliminates the need for off focal plane electronics, greatly reducing volume, mass, and power compared to conventional FPA implementations. A focal plane based on this ROIC will require less than 2 W of power on a 1×1-cm integrated circuit. The ROIC is fabricated of silicon using CMOS technology. It is designed to be indium bump bonded to a variety of detector materials including silicon PIN diodes, indium antimonide (InSb), indium gallium arsenide (In- GaAs), and mercury cadmium telluride (HgCdTe) detector arrays to provide coverage over a broad spectral range in the infrared, visible, and ultraviolet spectral ranges.
The art and science of missile defense sensor design
NASA Astrophysics Data System (ADS)
McComas, Brian K.
2014-06-01
A Missile Defense Sensor is a complex optical system, which sits idle for long periods of time, must work with little or no on-board calibration, be used to find and discriminate targets, and guide the kinetic warhead to the target within minutes of launch. A short overview of the Missile Defense problem will be discussed here, as well as, the top-level performance drivers, like Noise Equivalent Irradiance (NEI), Acquisition Range, and Dynamic Range. These top-level parameters influence the choice of optical system, mechanical system, focal plane array (FPA), Read Out Integrated Circuit (ROIC), and cryogenic system. This paper will not only discuss the physics behind the performance of the sensor, but it will also discuss the "art" of optimizing the performance of the sensor given the top level performance parameters. Balancing the sensor sub-systems is key to the sensor's performance in these highly stressful missions. Top-level performance requirements impact the choice of lower level hardware and requirements. The flow down of requirements to the lower level hardware will be discussed. This flow down directly impacts the FPA, where careful selection of the detector is required. The flow down also influences the ROIC and cooling requirements. The key physics behind the detector and cryogenic system interactions will be discussed, along with the balancing of subsystem performance. Finally, the overall system balance and optimization will be discussed in the context of missile defense sensors and expected performance of the overall kinetic warhead.
Bayerle-Eder, Michaela; Fuchsjäger-Mayrl, Gabriele; Sieder, Anna; Polska, Elzbieta; Roden, Michael; Stulnig, Thomas; Bischof, Martin G; Waldhäusl, Werner; Schmetterer, Leopold; Wolzt, Michael
2002-01-01
Improvement of endothelial function in hypercholesterolaemia is attributed to lipid lowering and to pleiotropic effects of statin therapy. We investigated whether responsiveness to inhibition of constitutive NO formation with N-monomethyl-L-arginine (L-NMMA) is improved after 7 and 28 days of pravastatin. Twelve female and four male subjects with mild or moderate primary hypercholesterolaemia were randomized to pravastatin (20 mg per oral (p.o.) n=8) or placebo (n=8) in a double blind parallel group design. Vascular responsiveness was studied by intravenous bolus infusions of L-NMMA (cumulative doses of 3 and 6 mg/kg). Mean arterial blood pressure (MAP) and pulse rate (PR) were measured noninvasively, pulsatile choroidal blood flow was assessed with laser interferometric measurement of fundus pulsation amplitudes (FPA) and renal plasma flow (RPF) was measured by the PAH clearance method. Pravastatin lowered plasma cholesterol levels by 16 and 24% after 7 and 28 days of treatment, respectively (P<0.01). L-NMMA caused comparable changes in MAP, PR and RPF between groups. L-NMMA reduced FPA to a similar extent in both groups before and after 7 days of treatment, but the response to L-NMMA was significantly enhanced after 28 days of pravastatin (21%; P<0.001 vs baseline) and greater than after placebo (15%; P<0.01 vs pravastatin). Pravastatin enhances responsiveness to L-NMMA in the ocular microvasculature. Improved responsiveness is associated with changes in total cholesterol levels.
Demosaicking for full motion video 9-band SWIR sensor
NASA Astrophysics Data System (ADS)
Kanaev, Andrey V.; Rawhouser, Marjorie; Kutteruf, Mary R.; Yetzbacher, Michael K.; DePrenger, Michael J.; Novak, Kyle M.; Miller, Corey A.; Miller, Christopher W.
2014-05-01
Short wave infrared (SWIR) spectral imaging systems are vital for Intelligence, Surveillance, and Reconnaissance (ISR) applications because of their abilities to autonomously detect targets and classify materials. Typically the spectral imagers are incapable of providing Full Motion Video (FMV) because of their reliance on line scanning. We enable FMV capability for a SWIR multi-spectral camera by creating a repeating pattern of 3x3 spectral filters on a staring focal plane array (FPA). In this paper we present the imagery from an FMV SWIR camera with nine discrete bands and discuss image processing algorithms necessary for its operation. The main task of image processing in this case is demosaicking of the spectral bands i.e. reconstructing full spectral images with original FPA resolution from spatially subsampled and incomplete spectral data acquired with the choice of filter array pattern. To the best of author's knowledge, the demosaicking algorithms for nine or more equally sampled bands have not been reported before. Moreover all existing algorithms developed for demosaicking visible color filter arrays with less than nine colors assume either certain relationship between the visible colors, which are not valid for SWIR imaging, or presence of one color band with higher sampling rate compared to the rest of the bands, which does not conform to our spectral filter pattern. We will discuss and present results for two novel approaches to demosaicking: interpolation using multi-band edge information and application of multi-frame super-resolution to a single frame resolution enhancement of multi-spectral spatially multiplexed images.
Odor Events in Surface and Treated Water: The Case of 1,3-Dioxane Related Compounds.
Quintana, Jordi; Vegué, Lídia; Martín-Alonso, Jordi; Paraira, Miquel; Boleda, M Rosa; Ventura, Francesc
2016-01-05
A study has been carried out to identify the origin of the odorous compounds at trace levels detected in surface waters and in Barcelona's tap water (NE Spain) which caused consumer complaints. The malodorous compounds were 2,5,5-trimethyl-1,3-dioxane (TMD) and 2-ethyl-5,5-dimethyl-1,3-dioxane (2EDD) which impart a distinctive sickening or olive-oil odor to drinking water at low ng/L levels. Flavor profile analysis (FPA) or threshold odor number (TON) were used for organoleptic purposes. Levels up to 749 ng/L for TMD and 658 ng/L for 2EDD were measured at the entrance of the drinking water treatment plant. Three wastewater treatment plants (WWTPs) using industrial byproducts coming from resin manufacturing plants to promote codigestion were found to be the origin of the event. Corrective measures were applied, including the prohibition to use these byproducts for codigestion in the WWTPs involved. A similar event was already recorded in the same area 20 years ago.
Jung, I K; Park, S C; Kim, S H; Kim, J H; Cha, N R; Bae, W R; Kim, H N; Cho, S A; Yoo, J W; Kim, B M; Lee, J H
2017-04-01
Coacervates are inevitably formed on scalp on using hair washing products. Our goal was to analyse the coacervates in detail to identify the part responsible for scalp stimulation. Shampoo that increases coacervate formation was applied to in vitro skin and was washed. The residue was then analysed using Fourier transform infrared spectroscopy-focal plane array (FTIR-FPA) and X-ray photoelectron microscopy (XPS). And HaCaT cells were used for irritant test of coacervate. Through this research, it was confirmed that the coacervate was a macromolecule structurally similar to a cationic polymer and contains an anionic surfactant. Its anionic surfactant was structurally semi-stable so that it released onto scalp when it absorbs moisture. Coacervate releases sulphate bonding into the matrix when it is exposed to water. Thus, the scalp stimulation would be expected. © 2016 Society of Cosmetic Scientists and the Société Française de Cosmétologie.
NASA Astrophysics Data System (ADS)
Levanon, Assaf; Yitzhaky, Yitzhak; Kopeika, Natan S.; Rozban, Daniel; Abramovich, Amir
2014-10-01
In recent years, much effort has been invested to develop inexpensive but sensitive Millimeter Wave (MMW) detectors that can be used in focal plane arrays (FPAs), in order to implement real time MMW imaging. Real time MMW imaging systems are required for many varied applications in many fields as homeland security, medicine, communications, military products and space technology. It is mainly because this radiation has high penetration and good navigability through dust storm, fog, heavy rain, dielectric materials, biological tissue, and diverse materials. Moreover, the atmospheric attenuation in this range of the spectrum is relatively low and the scattering is also low compared to NIR and VIS. The lack of inexpensive room temperature imaging systems makes it difficult to provide a suitable MMW system for many of the above applications. In last few years we advanced in research and development of sensors using very inexpensive (30-50 cents) Glow Discharge Detector (GDD) plasma indicator lamps as MMW detectors. This paper presents three kinds of GDD sensor based lamp Focal Plane Arrays (FPA). Those three kinds of cameras are different in the number of detectors, scanning operation, and detection method. The 1st and 2nd generations are 8 × 8 pixel array and an 18 × 2 mono-rail scanner array respectively, both of them for direct detection and limited to fixed imaging. The last designed sensor is a multiplexing frame rate of 16x16 GDD FPA. It permits real time video rate imaging of 30 frames/ sec and comprehensive 3D MMW imaging. The principle of detection in this sensor is a frequency modulated continuous wave (FMCW) system while each of the 16 GDD pixel lines is sampled simultaneously. Direct detection is also possible and can be done with a friendly user interface. This FPA sensor is built over 256 commercial GDD lamps with 3 mm diameter International Light, Inc., Peabody, MA model 527 Ne indicator lamps as pixel detectors. All three sensors are fully supported by software Graphical Unit Interface (GUI). They were tested and characterized through different kinds of optical systems for imaging applications, super resolution, and calibration methods. Capability of the 16x16 sensor is to employ a chirp radar like method to produced depth and reflectance information in the image. This enables 3-D MMW imaging in real time with video frame rate. In this work we demonstrate different kinds of optical imaging systems. Those systems have capability of 3-D imaging for short range and longer distances to at least 10-20 meters.
Analysis for signal-to-noise ratio of hyper-spectral imaging FTIR interferometer
NASA Astrophysics Data System (ADS)
Li, Xun-niu; Zheng, Wei-jian; Lei, Zheng-gang; Wang, Hai-yang; Fu, Yan-peng
2013-08-01
Signal-to-noise Ratio of hyper-spectral imaging FTIR interferometer system plays a decisive role on the performance of the instrument. It is necessary to analyze them in the development process. Based on the simplified target/background model, the energy transfer model of the LWIR hyper-spectral imaging interferometer has been discussed. The noise equivalent spectral radiance (NESR) and its influencing factors of the interferometer system was analyzed, and the signal-to-noise(SNR) was calculated by using the properties of NESR and incident radiance. In a typical application environment, using standard atmospheric model of USA(1976 COESA) as a background, and set a reasonable target/background temperature difference, and take Michelson spatial modulation Fourier Transform interferometer as an example, the paper had calculated the NESR and the SNR of the interferometer system which using the commercially LWIR cooled FPA and UFPA detector. The system noise sources of the instrument were also analyzed in the paper. The results of those analyses can be used to optimize and pre-estimate the performance of the interferometer system, and analysis the applicable conditions of use different detectors. It has important guiding significance for the LWIR interferometer spectrometer design.
Additional targets of the Arabidopsis autonomous pathway members, FCA and FY.
Marquardt, S; Boss, P K; Hadfield, J; Dean, C
2006-01-01
A central player in the Arabidopsis floral transition is the floral repressor FLC, the MADS-box transcriptional regulator that inhibits the activity of genes required to switch the meristem from vegetative to floral development. One of the many pathways that regulate FLC expression is the autonomous promotion pathway composed of FCA, FY, FLD, FPA, FVE, LD, and FLK. Rather than a hierarchical set of activities the autonomous promotion pathway comprises sub-pathways of genes with different biochemical functions that all share FLC as a target. One sub-pathway involves FCA and FY, which interact to regulate RNA processing of FLC. Several of the identified components (FY, FVE, and FLD) are homologous to yeast and mammalian proteins with rather generic roles in gene regulation. So why do mutations in these genes specifically show a late-flowering phenotype in Arabidopsis? One reason, found during the analysis of fy alleles, is that the mutant alleles identified in flowering screens can be hypomorphic, they still have partial function. A broader role for the autonomous promotion pathway is supported by a microarray analysis which has identified genes mis-regulated in fca mutants, and whose expression is also altered in fy mutants.
1980-01-01
aatrlx beadlag it is beneficial to compere the aeasered coaposite properties to theoreticel proper- ties eetlaeted fro» the coastltueat fiber end...v/o ueldlrectlmuei FP/A1 laminate. The calculated constants ere compere « to neaoured values in Table If «ad ere seem to be good agreement. The...Figure 16 comperes the specific unidirectional prop- erties (property/density) with structural metals Including titanium alloy (Ti-6A-4V) and 403
1981-01-01
for the ~AUG18IS~ 1W Symposium on Comites and Advanced Materials*M sponsored by the American Ceramic Society Coco Beach, Florida, January 18424, 1981E...properties of cFP-A203 fiber reinforced composites prepared by liquid metal infiltration f a techniques. The first approach was the incorporation of a...coated FP-A1203 fibers in the composites. This coating is readily wet by molten aluminum and permitted the use of more conventional aluminum alloys
2014-09-30
Minvielle- Sebastia, L. and Guinet, C. (2008b). Diet of the social groups of long-finned pilot whales (Globicephala melas ) in the Strait of Gibraltar. Marine...structure of long-finned pilot whales (Globicephala melas ) in the Strait of Gibraltar. Acta Ethologica 11, 81-94. DeRuiter, S. L., Boyd, I. L...Aoki Kagari A, Lam F-Pa, Kvadsheim PH, Huisman J, Tyack PL (2014): The social contect of individual foraging behaviour in long-finned pilot whales (Globicephala melas ). Behaviour 151: 1453-77. [published, refereed
Development of imaging FTS for astronomy
NASA Astrophysics Data System (ADS)
Grandmont, Frederic
2002-05-01
The Next Generation Space Telescope project in its early definition phases has given birth to many innovations in instrumentation for astronomy by providing funding for industries in an area often considered less lucrative and hence of lower interest. New alliances were formed with universities and institutions and the knowledge exchange lead to very interesting new concepts. The Imaging version of the Fourier Transform Spectrometer (IFTS), a derivative of the classical Michelson interferometer that has been used successfully in spectroscopy for decades, was introduced in military applications in the mid 80's with small FPA (- 2 X 4).
Photogrammetry of the Map Instrument in a Cryogenic Vacuum Environment
NASA Technical Reports Server (NTRS)
Hill, M.; Packard, E.; Pazar, R.
2000-01-01
MAP Instrument requirements dictated that the instruments Focal Plane Assembly (FPA) and Thermal Reflector System (TRS) maintain a high degree of structural integrity at operational temperatures (< 50K). To verify integrity at these extremes, an elaborate test fixture was constructed to provide a large cryogenic (< 20K) radiative environment and a mobile photogrammetry camera. This paper will discuss MAP's Instrument requirements, how those requirements were verified using photogrammetry, and the test setup used to provide the environment and camera movement needed to verify the instrument's requirements.
GIFTS SM EDU Data Processing and Algorithms
NASA Technical Reports Server (NTRS)
Tian, Jialin; Johnson, David G.; Reisse, Robert A.; Gazarik, Michael J.
2007-01-01
The Geosynchronous Imaging Fourier Transform Spectrometer (GIFTS) Sensor Module (SM) Engineering Demonstration Unit (EDU) is a high resolution spectral imager designed to measure infrared (IR) radiances using a Fourier transform spectrometer (FTS). The GIFTS instrument employs three Focal Plane Arrays (FPAs), which gather measurements across the long-wave IR (LWIR), short/mid-wave IR (SMWIR), and visible spectral bands. The raw interferogram measurements are radiometrically and spectrally calibrated to produce radiance spectra, which are further processed to obtain atmospheric profiles via retrieval algorithms. This paper describes the processing algorithms involved in the calibration stage. The calibration procedures can be subdivided into three stages. In the pre-calibration stage, a phase correction algorithm is applied to the decimated and filtered complex interferogram. The resulting imaginary part of the spectrum contains only the noise component of the uncorrected spectrum. Additional random noise reduction can be accomplished by applying a spectral smoothing routine to the phase-corrected blackbody reference spectra. In the radiometric calibration stage, we first compute the spectral responsivity based on the previous results, from which, the calibrated ambient blackbody (ABB), hot blackbody (HBB), and scene spectra can be obtained. During the post-processing stage, we estimate the noise equivalent spectral radiance (NESR) from the calibrated ABB and HBB spectra. We then implement a correction scheme that compensates for the effect of fore-optics offsets. Finally, for off-axis pixels, the FPA off-axis effects correction is performed. To estimate the performance of the entire FPA, we developed an efficient method of generating pixel performance assessments. In addition, a random pixel selection scheme is designed based on the pixel performance evaluation.
Predicting the optical observables for nucleon scattering on even-even actinides
NASA Astrophysics Data System (ADS)
Martyanov, D. S.; Soukhovitskiĩ, E. Sh.; Capote, R.; Quesada, J. M.; Chiba, S.
2017-09-01
The previously derived Lane consistent dispersive coupled-channel optical model for nucleon scattering on 232Th and 238U nuclei is extended to describe scattering on even-even actinides with Z = 90-98. A soft-rotator-model (SRM) description of the low-lying nuclear structure is used, where the SRM Hamiltonian parameters are adjusted to the observed collective levels of the target nucleus. SRM nuclear wave functions (mixed in K quantum number) have been used to calculate the coupling matrix elements of the generalized optical model. The “effective” deformations that define inter-band couplings are derived from the SRM Hamiltonian parameters. Conservation of nuclear volume is enforced by introducing a dynamic monopolar term to the deformed potential, leading to additional couplings between rotational bands. The fitted static deformation parameters are in very good agreement with those derived by Wang and collaborators using the Weizsäcker-Skyrme global mass model (WS4), allowing use of the latter to predict cross sections for nuclei without experimental data. A good description of the scarce “optical” experimental database is achieved. SRM couplings and volume conservation allow a precise calculation of the compound-nucleus formation cross sections, which is significantly different from that calculated with rigid-rotor potentials coupling the ground-state rotational band. The derived parameters can be used to describe both neutron- and proton-induced reactions. Supported by International Atomic Energy Agency, through the IAEA Research Contract 19263, by the Spanish Ministry of Economy and Competitivity under Contracts FPA2014-53290-C2-2-P and FPA2016-77689-C2-1-R.
New technologies for HWIL testing of WFOV, large-format FPA sensor systems
NASA Astrophysics Data System (ADS)
Fink, Christopher
2016-05-01
Advancements in FPA density and associated wide-field-of-view infrared sensors (>=4000x4000 detectors) have outpaced the current-art HWIL technology. Whether testing in optical projection or digital signal injection modes, current-art technologies for infrared scene projection, digital injection interfaces, and scene generation systems simply lack the required resolution and bandwidth. For example, the L3 Cincinnati Electronics ultra-high resolution MWIR Camera deployed in some UAV reconnaissance systems features 16MP resolution at 60Hz, while the current upper limit of IR emitter arrays is ~1MP, and single-channel dual-link DVI throughput of COTs graphics cards is limited to 2560x1580 pixels at 60Hz. Moreover, there are significant challenges in real-time, closed-loop, physics-based IR scene generation for large format FPAs, including the size and spatial detail required for very large area terrains, and multi - channel low-latency synchronization to achieve the required bandwidth. In this paper, the author's team presents some of their ongoing research and technical approaches toward HWIL testing of large-format FPAs with wide-FOV optics. One approach presented is a hybrid projection/injection design, where digital signal injection is used to augment the resolution of current-art IRSPs, utilizing a multi-channel, high-fidelity physics-based IR scene simulator in conjunction with a novel image composition hardware unit, to allow projection in the foveal region of the sensor, while non-foveal regions of the sensor array are simultaneously stimulated via direct injection into the post-detector electronics.
Günther, A; Mosavi, P; Ruppert, C; Heinemann, S; Temmesfeld, B; Velcovsky, H G; Morr, H; Grimminger, F; Walmrath, D; Seeger, W
2000-06-01
Bronchoalveolar lavage fluids (BALF) from patients with hypersensitivity pneumonitis (HP; n = 35), idiopathic pulmonary fibrosis (IPF, n = 41) and sarcoidosis (SARC, n = 48) were investigated for alterations in the alveolar hemostatic balance. Healthy individuals (n = 21) served as Controls. Procoagulant activity (PCA), tissue factor (TF) activity and F VII activity were assessed by means of specific recalcification assays. The overall fibrinolytic activity (FA) was measured using the (125)I-labeled fibrin plate assay. Fibrinopeptide A (FP-A), D-Dimer, plasminogen activators (PA) of the urokinase (u-PA) or tissue type (t-PA), PA-inhibitor I (PAI-1) and alpha2-antiplasmin (alpha2-AP) were determined by ELISA technique. As compared to Controls, all groups with interstitial lung disease (ILD) displayed an increase in BALF PCA by approximately one order of magnitude, and this was ascribed to enhanced TF activity by >98%. Accordingly, F VII-activity was increased in all ILD groups, and elevated FP-A levels were noted. There was no significant difference in procoagulant activities between the different ILD entities, but the increase in TF was significantly correlated with deterioration of lung compliance. Overall fibrinolytic activity did not significantly differ between ILD entities and Controls, although some reduction in IPF subjects was observed. Nevertheless, changes in the profile of the different pro- and antifibrinolytic compounds were noted. U-PA, but not t-PA levels were significantly reduced in all ILD groups. alpha2-AP was markedly elevated throughout, whereas PAI-1 levels were lowered. As a balance of
AIRS-Light Instrument Concept and Critical Technology Development
NASA Technical Reports Server (NTRS)
Maschhoff, Kevin
2001-01-01
Understanding Earth's climate, atmospheric transport mechanisms, and the hydrologic cycle requires a precise knowledge of global atmospheric circulation, temperature profiles, and water vapor distribution. The accuracy of advanced sounders such as AIRS/AMSU/HSB on NASA's Aqua spacecraft can match radiosonde accuracy. It is essential to fold those capabilities fully into the NPOESS, enabling soundings of radiosonde accuracy, every 6 hours around the globe on an operational basis. However, the size, mass, power demands, and thermal characteristics of the Aqua sounding instrument suite cannot be accommodated on the NPOESS spacecraft. AIRS-Light is an instrument concept, developed under the Instrument Incubator Program, which provides IR sounding performance identical to the AIRS instrument, but uses advances in HgCdTe FPA technology and pulse tube cooler technology, as well as design changes to dramatically reduce the size, mass, and power demand, allowing AIRS-Light to meet all NPOESS spacecraft interface requirements. The instrument concept includes substantial re-use of AIRS component designs, including the complex AIRS FPA, to reduce development risk and cost. The AIRS-Light Instrument Incubator program fostered the development of photovoltaic-mode HgCdTe detector array technology for the 13.5-15.4 micron band covered by photoconductive-mode HgCdTe arrays in AIRS, achieved state of the art results in this band, and substantially reduced the development risk for this last new technology needed for AIRS-Light implementation, A demonstration of a prototype 14.5-15.4 micron band IRFPA in a reduced heat-load dewar together with the IMAS pulse tube cryocooler is in progress.
Infrared image enhancement based on the edge detection and mathematical morphology
NASA Astrophysics Data System (ADS)
Zhang, Linlin; Zhao, Yuejin; Dong, Liquan; Liu, Xiaohua; Yu, Xiaomei; Hui, Mei; Chu, Xuhong; Gong, Cheng
2010-11-01
The development of the un-cooled infrared imaging technology from military necessity. At present, It is widely applied in industrial, medicine, scientific and technological research and so on. The infrared radiation temperature distribution of the measured object's surface can be observed visually. The collection of infrared images from our laboratory has following characteristics: Strong spatial correlation, Low contrast , Poor visual effect; Without color or shadows because of gray image , and has low resolution; Low definition compare to the visible light image; Many kinds of noise are brought by the random disturbances of the external environment. Digital image processing are widely applied in many areas, it can now be studied up close and in detail in many research field. It has become one kind of important means of the human visual continuation. Traditional methods for image enhancement cannot capture the geometric information of images and tend to amplify noise. In order to remove noise and improve visual effect. Meanwhile, To overcome the above enhancement issues. The mathematical model of FPA unit was constructed based on matrix transformation theory. According to characteristics of FPA, Image enhancement algorithm which combined with mathematical morphology and edge detection are established. First of all, Image profile is obtained by using the edge detection combine with mathematical morphological operators. And then, through filling the template profile by original image to get the ideal background image, The image noise can be removed on the base of the above method. The experiments show that utilizing the proposed algorithm can enhance image detail and the signal to noise ratio.
Effect of acetyl salicylic acid on increased production of thromboxane after aortic graft surgery.
Lewin, J; Swedenborg, J; Egberg, N; Vesterqvist, O; Green, K
1989-06-01
Contact between blood and foreign surfaces, e.g. vascular grafts, causes activation and release of platelets. One consequence of platelet activation is production of thromboxane A2 (TxA2). The physiological effects of TxA2, i.e. platelet aggregation and vaso-constriction are counteracted by another prostanoid, prostacyclin (PGI2). Acetylsalicylic acid (ASA) causes a longlasting inhibition of platelet TxA2 production and a more shortlasting inhibition of PGI2 production. The present study examines TxA2 and PGI2 synthesis in patients receiving synthetic arterial grafts, some of which were treated with ASA. The prostanoid synthesis was evaluated by measurement of their main urinary metabolites with gas chromatography-mass spectrometry. Platelet release was evaluated by measurements of beta-thromboglobulin (beta-TG) and the plasma coagulation by measurements of fibrinopeptide A (FPA). These compounds were also measured in urine in order to avoid artifacts caused by activation of platelets and plasma coagulation during blood sampling. Following replacement of the abdominal aorta with a synthetic vascular graft there was a marked increase in the synthesis of TxA2 and PGI2. Increased levels of beta-TG and FPA were also demonstrated. Administration of ASA on the first and second postoperative days significantly reduced the synthesis of TxA2 but caused no significant effects on the other parameters measured. It is concluded that ASA may be beneficial in the postoperative period since it counteracts TxA2 with vasoconstricting and platelet aggregating properties but leaves PGI2 with vasodilating and antiaggregating properties relatively uneffected.
Choroidal microcirculation in patients with rotary cardiac assist device.
Polska, Elzbieta; Schima, Heinrich; Wieselthaler, Georg; Schmetterer, Leopold
2007-06-01
In recent years, fully implanted rotary blood pumps have been used for long-term cardiac assist in patients with end-stage heart failure. With these pumps, the pulsatility of arterial blood flow and arterial pressure pulse is considerably reduced. Effects on end-organ perfusion, particularly microcirculation, have been assessed. The ocular choroid offers a unique opportunity to study the pulsatile component of blood flow by measurement of fundus pulsation amplitude (FPA) as well as the microcirculation by laser Doppler flowmetry. Both techniques were applied in three male patients with rotary pumps (MicroMed DeBakey VAD), in whom pump velocity was adjusted to four levels of flow between individual minimal need and maximal support. In addition, blood flow velocities in the ophthalmic artery (peak, end-diastolic and mean flow velocity--PSV, EDV and MFV, respectively) were measured using color Doppler imaging. Systolic blood pressure increased by 6 to 22 mm Hg with increasing support. At maximal support FPA was reduced by -60% to -52% as compared with minimal pump support. Blood flow in the choroidal microvasculature, however, did not show relevant changes. A reduction in PSV (-31%, range -47% to -21%) and a pronounced rise in EDV (+93%, range +28% to +147%) was observed, whereas MFV was independent of pump flow. Our data indicate that mean choroidal blood flow is maintained when pump support is varied within therapeutic values, whereas the ratio of pulsatile to non-pulsatile choroidal flow changes. This study shows that, in patients with ventricular assist devices, a normal perfusion rate in the ocular microcirculation is maintained over a wide range of support conditions.
Common aperture multispectral spotter camera: Spectro XR
NASA Astrophysics Data System (ADS)
Petrushevsky, Vladimir; Freiman, Dov; Diamant, Idan; Giladi, Shira; Leibovich, Maor
2017-10-01
The Spectro XRTM is an advanced color/NIR/SWIR/MWIR 16'' payload recently developed by Elbit Systems / ELOP. The payload's primary sensor is a spotter camera with common 7'' aperture. The sensor suite includes also MWIR zoom, EO zoom, laser designator or rangefinder, laser pointer / illuminator and laser spot tracker. Rigid structure, vibration damping and 4-axes gimbals enable high level of line-of-sight stabilization. The payload's list of features include multi-target video tracker, precise boresight, strap-on IMU, embedded moving map, geodetic calculations suite, and image fusion. The paper describes main technical characteristics of the spotter camera. Visible-quality, all-metal front catadioptric telescope maintains optical performance in wide range of environmental conditions. High-efficiency coatings separate the incoming light into EO, SWIR and MWIR band channels. Both EO and SWIR bands have dual FOV and 3 spectral filters each. Several variants of focal plane array formats are supported. The common aperture design facilitates superior DRI performance in EO and SWIR, in comparison to the conventionally configured payloads. Special spectral calibration and color correction extend the effective range of color imaging. An advanced CMOS FPA and low F-number of the optics facilitate low light performance. SWIR band provides further atmospheric penetration, as well as see-spot capability at especially long ranges, due to asynchronous pulse detection. MWIR band has good sharpness in the entire field-of-view and (with full HD FPA) delivers amount of detail far exceeding one of VGA-equipped FLIRs. The Spectro XR offers level of performance typically associated with larger and heavier payloads.
Test results for the 201.25 MHZ tetrode power amplifier at LANSCE
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lyles, J. T.; Archuletta, S.; Davis, J. L.
2004-01-01
A new RF amplifier has been constructed for use as the intermediate power amplifier stage for the 201.25 MHz Alvarez DTL at the Los Alamos Neutron Science Center (LANSCE). It is part of a larger upgrade to replace the entire RF plant with a new generation of components. The new RF power system under development will enable increased peak power with higher duty factor. The first tank requires over 400 kW of RF power. This can be satisfied using the TH781 tetrode in a THALES cavity amplifier. The same stage will be also used to drive a TH628 Diacrode(reg. sign)more » final power amplifier for each of the three remaining DTL tanks. In this application, it will only be required to deliver approximately 150 kW of peak power. Details of the system design, layout for DTL 1, and test results will be presented. The Thales cavity amplifier and TH78I tetrode have been tested for two upcoming requirements at LANSCE. As an IPA to drive a future TH628 Diacrode(reg. sign) FPA with 120-150 kW, the amplifier provided over 16 dB power gain with 50% efficiency or better. As a stand-alone FPA to drive a 5 MeV Alvarez DTI, tank, the amplifier provided 13.5 dB power gain with 50% efficiency or better. It can also be used to drive a 200 MHz RFQ in the future. Power supplies, driver amplifier and coaxial circulators are being specified for the complete installation.« less
NASA Technical Reports Server (NTRS)
Wang, Zhipeng; Xiong, Xiaoxiong
2017-01-01
The Moderate Resolution Imaging Spectroradiometer (MODIS) instruments aboard Terra and Aqua satellites are radiometrically calibrated on-orbit with a set of onboard calibrators (OBCs), including a solar diffuser, a blackbody, and a space view port through which the detectors can view the dark space. As a whisk-broom scanning spectroradiometer, thirty-six MODIS spectral bands are assembled in the along-scan direction on four focal plane assemblies (FPAs). These bands capture images of the same target sequentially with the motion of a scan mirror. Then the images are coregistered onboard by delaying the appropriate band-dependent amount of time, depending on the band locations on the FPA. While this coregistration mechanismis functioning well for the far-field remote targets such as earth view scenes or the moon, noticeable band-to-band misregistration in the along-scan direction has been observed for near field targets, particularly in OBCs. In this paper, the misregistration phenomenon is presented and analyzed. It is concluded that the root cause of the misregistration is that the rotating element of the instrument, the scan mirror, is displaced from the focus of the telescope primary mirror. The amount of the misregistrationis proportional to the band location on the FPA and is inversely proportional to the distance between the target and the scan mirror. The impact of this misregistration on the calibration of MODIS bands is discussed. In particular, the calculation of the detector gain coefficient m1of bands 8-16 (412 nm 870 nm) is improved by up to 1.5% for Aqua MODIS.
III-V infrared research at the Jet Propulsion Laboratory
NASA Astrophysics Data System (ADS)
Gunapala, S. D.; Ting, D. Z.; Hill, C. J.; Soibel, A.; Liu, John; Liu, J. K.; Mumolo, J. M.; Keo, S. A.; Nguyen, J.; Bandara, S. V.; Tidrow, M. Z.
2009-08-01
Jet Propulsion Laboratory is actively developing the III-V based infrared detector and focal plane arrays (FPAs) for NASA, DoD, and commercial applications. Currently, we are working on multi-band Quantum Well Infrared Photodetectors (QWIPs), Superlattice detectors, and Quantum Dot Infrared Photodetector (QDIPs) technologies suitable for high pixel-pixel uniformity and high pixel operability large area imaging arrays. In this paper we report the first demonstration of the megapixel-simultaneously-readable and pixel-co-registered dual-band QWIP focal plane array (FPA). In addition, we will present the latest advances in QDIPs and Superlattice infrared detectors at the Jet Propulsion Laboratory.
2007-01-01
extremely important. In this paper we discuss Teledyne Imaging Sensor’s (TIS)# H4RG-10 CMOS-Hybrid Focal Plane Assembly (FPA)@. The H4RG-10 is a...receipt of a loaned engineering grade unit ( EGU ) that was used initially for electronics set up and testing. We plan on irradiating the EGU at a later...persistence, since exposure to high energy proton flux that is typical of the space environment results in the generation of new traps in the detector
Design of Magnetic Shielding and Field Coils for a TES X-Ray Microcalorimeter Test Platform
NASA Technical Reports Server (NTRS)
Miniussi, Antoine R.; Adams, Joseph S.; Bandler, Simon R.; Chervenak, James A.; Datesman, Aaron M.; Doriese, William B.; Eckart, Megan E.; Finkbeiner, Fred M.; Kelley, Richard L.; Kilbourne, Caroline A.;
2017-01-01
The performance of Transition-Edge Sensors (TES) and their SQUID multiplexed read-outs are very sensitive to the ambient magnetic field from Earth and fluctuations that can arise due to fluctuating magnetic fields outside of the focal plane assembly from the Adiabatic Demagnetization Refrigerator (ADR).Thus, the experimental platform we are building to test the FPA of the X-ray Integral Field Unit (X-IFU) of the Athena mission needs to include a series of shields and a coil in order to meet the following requirement of magnetic field density and uniformity.
InGaAs focal plane arrays for low-light-level SWIR imaging
NASA Astrophysics Data System (ADS)
MacDougal, Michael; Hood, Andrew; Geske, Jon; Wang, Jim; Patel, Falgun; Follman, David; Manzo, Juan; Getty, Jonathan
2011-06-01
Aerius Photonics will present their latest developments in large InGaAs focal plane arrays, which are used for low light level imaging in the short wavelength infrared (SWIR) regime. Aerius will present imaging in both 1280x1024 and 640x512 formats. Aerius will present characterization of the FPA including dark current measurements. Aerius will also show the results of development of SWIR FPAs for high temperaures, including imagery and dark current data. Finally, Aerius will show results of using the SWIR camera with Aerius' SWIR illuminators using VCSEL technology.
Men Too--a retrospective view of the Family Planning Association's male responsibility campaign.
Wellings, K
1986-01-01
England's Family Planning Association's (FPA) MEN TOO campaign evolved from the recognition that men seemed to receive less support and encouragement than women in their involvement in the emotional aspects of relationships, family planning, and child rearing. Created out of a concern for balancing the selective attention given to men and women, the longterm goal of the MEN TOO campaign was to support the growing number of men who are concerned about increasing their participation in emotional expression, family planning, child rearing and related areas and to explore ways of improving the information and education services that contribute to a better understanding of these issues. The shortterm project goals were to: raise the "unspoken issues" for public debate; encourage more communication and an improved quality in personal and sexual relationships; and raise the support for effective contraceptive use in sexual relationships. Prior to the publicity campaign a select bibliography, a document outlining the need for and general aims of the MEN TOO project, and a report indicating that family planning services needed to be more flexible and accommodating to men were prepared. A press conference officially launched the MEN TOO project. During the autumn of 1984 and the spring of 1985 public service announcements were transmitted on all 9 of the independent television stations participating in the scheme. The FPA's 1-day conference, "Men, Sex and Relationships" in March 1985, in London. 400 delegates, attended both professional and laypersons, about 1/3 of them men. To give the initial impetus to changing the general atmosphere within family planning clinics and to changing staff attitudes toward men, a letter was sent from the FPA's Secretary General to all District Medical Officers, with copies to Senior Family Planning Officers and to District Health Education Officers, describing the campaign and expressing the hope that more men would come forward to seek contraceptive advice. All family planning clinics were given window stickers welcoming MEN TOO together with details of the project. 4 experimental courses serving 20 participants each were organized by the PFA Education Unit, designed specifically for clinic receptionists. These courses aimed to increase the communication skills of the reeptionists and to provide some factual information about contraception and preventive health care. To meet the needs of young men with learning problems, the Brook clinics produced an explanatory "teaching the use of the sheath" chart to be used as a prompt by clinic staff. A spinoff of the MEN TOO campaign was the establishment of 2 WELL MAN clinics. Early feedback is encouraging. Family planning attendance figures for 1984 showed the highest ever attendance by men.
1977-01-01
Men must be made to understand the value of family planning - particularly in societies where men hold the power of decision in the family. Dr. Kotha Pannikar, chairman of the Kedah Family Planning Association (FPA) in Malaysia, illustrated this point in discussion which followed the Consultation of Medical and Communication Fieldworkers conference in Kuala Lumpur in August, with a story about 1 of her own patients. When the girl, who had a rheumatic heart, was 16, Dr. Pannikar advised the parents that she needed cardiac surgery if she were to be a healthy wife and mother. But the parents lived some distance from Dr. Pannikar's surgery and did not heed the advice. The girl was married to a carpenter from a traditional Chinese family, in which "the man is lord and master." Her new home had no piped water, and in additional to normal domestic tasks she had to carry water from a source 1 1/2 miles agay. In the 7th month of her 1st pregnancy, she went into cardiac failure. After the 3rd pregnancy and a 3rd cardiac failure, Dr. Pannikar tried to arrange a sterilization "but we could not get consent - her husband refused to turn up at the hospital." When the girl was admitted to hospital 6 months into her 4th pregnancy, Dr. Pannikar got hold of her patient's mother-in-law. "I told her if she wanted a servant in the house, it was easy to get one. But no servant would look after her grandchildren the way their mother would. I told her if she wanted to save the girl's life she had better speak to her son." During the 4th delivery, the girl went into cardiac arrest and spent 2 weeks in intensive care. The mother-in-law prevailed upon her son to at least consent, and the girl was sterilized before she left hospital. But "it was a very near thing," Dr. Pannikar recalls "and it wouldn't have happened if the husband had felt he was responsible in parenthood." The Kedah FPA makes special efforts to reach men. Dr. Pannikar herself talks to men's organizations like the Lions and Rotary Clubs, and arranges education programs for trade unions and workers on the rubber estates. She thinks women need to be told repeatedly that they have a basic human right to choose whether they want to have a baby, and when. "Women feel," she says, "that their only function is to cook, wash clothes and feed the baby. We need to tell them they have a part to play in the society of today because their children will be the citizens of tomorrow."o full text
Thermal architecture of the SPICA/SAFARI instrument
NASA Astrophysics Data System (ADS)
Charles, Ivan; Duband, Lionel; Duval, Jean-Marc; Jackson, Brian; Jellema, Willem; Kooijman, Peter Paul; Luchier, Nicolas; Tirolien, Thierry; van Weers, Henk
2012-09-01
The SAFARI instrument is a far infrared imaging spectrometer that is a core instrument of the SPICA mission. Thanks to the large (3 meter) SPICA cold telescope, the ultra sensitive detectors and a powerful Fourier Transform Spectrometer, this instrument will give access to the faintest light never observed in the 34 μm - 210 μm bandwidth with a high spectral resolution. To achieve this goal, TES detectors, that need to be cooled at a temperature as low as 50 mK, have been chosen. The thermal architecture of the SAFARI focal plane unit (FPU) which fulfils the TES detector thermal requirements is presented. In particular, an original 50 mK cooler concept based on a sorption cooler in series with an adiabatic demagnetization refrigerator will be used. The thermal design of the detector focal plane array (FPA) that uses three temperature stages to limit the loads on the lowest temperature stage, will be also described. The current SAFARI thermal budget estimations are presented and discussed regarding the limited SPICA allocations. Finally, preliminary thermal sensitivity analysis dealing with thermal stability requirements is presented.
Ricor's Nanostar water vapor compact cryopump: applications and model overview
NASA Astrophysics Data System (ADS)
Harris, Rodney S.; Nachman, Ilan; Tauber, Tomer; Kootzenko, Michael; Barak, Boris; Aminov, Eli; Gover, Dan
2017-05-01
Ricor Systems has developed a compact, single stage cryopump that fills the gap where GM and other type cryopumps can't fit in. Stirling cycle technology is highly efficient and is the primary cryogenic technology for use in IR, SWIR, HOT FPA, and other IR detector technology in military, security, and aerospace applications. Current GM based dual stage cryopumps have been the legacy type water vapor pumping system for more than 50 years. However, the typically large cryopanel head, compressor footprint, and power requirements make them not cost and use effective for small, tabletop evaporation / sputtering systems, portable analysis systems, and other systems requiring small volume vacuum creation from medium, high, and UHV levels. This single stage cryopump works well in-line with diffusion and molecular turbopumps. Studies have shown effective cooperation with non-evaporable getter technology as well for UHV levels. Further testing in this area are ongoing. Temperatures created by Stirling cycle cryogenic coolers develop a useful temperature range of 40 to 150K. Temperatures of approximately 100 K are sufficient to condense water and all hydrocarbons oil vapors.
Mintenig, S M; Int-Veen, I; Löder, M G J; Primpke, S; Gerdts, G
2017-01-01
The global presence of microplastic (MP) in aquatic ecosystems has been shown by various studies. However, neither MP concentrations nor their sources or sinks are completely known. Waste water treatment plants (WWTPs) are considered as significant point sources discharging MP to the environment. This study investigated MP in the effluents of 12 WWTPs in Lower Saxony, Germany. Samples were purified by a plastic-preserving enzymatic-oxidative procedure and subsequent density separation using a zinc chloride solution. For analysis, attenuated total reflection Fourier-transform infrared spectroscopy (ATR-FT-IR) and focal plane array (FPA)-based transmission micro-FT-IR imaging were applied. This allowed the identification of polymers of all MP down to a size of 20 μm. In all effluents MP was found with quantities ranging from 0 to 5 × 10 1 m -3 MP > 500 μm and 1 × 10 1 to 9 × 10 3 m -3 MP < 500 μm. By far, polyethylene was the most frequent polymer type in both size classes. Quantities of synthetic fibres ranged from 9 × 10 1 to 1 × 10 3 m -3 and were predominantly made of polyester. Considering the annual effluxes of tested WWTPs, total discharges of 9 × 10 7 to 4 × 10 9 MP particles and fibres per WWTP could be expected. Interestingly, one tertiary WWTP had an additionally installed post-filtration that reduced the total MP discharge by 97%. Furthermore, the sewage sludge of six WWTPs was examined and the existence of MP, predominantly polyethylene, revealed. Our findings suggest that WWTPs could be a sink but also a source of MP and thus can be considered to play an important role for environmental MP pollution. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.
Cincinelli, Alessandra; Scopetani, Costanza; Chelazzi, David; Lombardini, Emilia; Martellini, Tania; Katsoyiannis, Athanasios; Fossi, Maria Cristina; Corsolini, Simonetta
2017-05-01
This is the first survey to investigate the occurrence and extent of microplastic (MPs) contamination in sub surface waters collected near-shore and off-shore the coastal area of the Ross Sea (Antarctica). Moreover, a non-invasive method to analyze MPs, consisting in filtration after water sampling and analysis of the dried filter through Fourier Transform Infrared Spectroscopy (FTIR) 2D Imaging, using an FPA detector, was proposed. The non-invasiveness of analytical set-up reduces potential bias and allows subsequent analysis of the filter sample for determination of other classes of contaminants. MPs ranged from 0.0032 to 1.18 particle per m 3 of seawater, with a mean value of 0.17 ± 0.34 particle m -3 , showing concentrations lower than those found in the oceans worldwide. MPs included fragments (mean 71.9 ± 21.6%), fibers (mean 12.7 ± 14.3%), and others (mean 15.4 ± 12.8%). The presence of different types of MPs was confirmed by FTIR spectroscopy, with predominant abundance of polyethylene and polypropylene. The potential environmental impact arising from scientific activities, such as marine activities for scientific purposes, and from the sewage treatment plant, was also evidenced. Copyright © 2017 Elsevier Ltd. All rights reserved.
LWIR pupil imaging and longer-term calibration stability
NASA Astrophysics Data System (ADS)
LeVan, Paul D.; Sakoglu, Ünal
2016-09-01
A previous paper described LWIR pupil imaging, and an improved understanding of the behavior of this type of sensor for which the high-sensitivity focal plane array (FPA) operated at higher flux levels includes a reversal in signal integration polarity. We have since considered a candidate methodology for efficient, long-term calibration stability that exploits the following two properties of pupil imaging: (1) a fixed pupil position on the FPA, and (2) signal levels from the scene imposed on significant but fixed LWIR background levels. These two properties serve to keep each pixel operating over a limited dynamic range that corresponds to its location in the pupil and to the signal levels generated at this location by the lower and upper calibration flux levels. Exploiting this property for which each pixel of the Pupil Imager operates over its limited dynamic range, the signal polarity reversal between low and high flux pixels, which occurs for a circular region of pixels near the upper edges of the pupil illumination profile, can be rectified to unipolar integration with a two-level non-uniformity correction (NUC). Images corrected real-time with standard non-uniformity correction (NUC) techniques, are still subject to longer-term drifts in pixel offsets between recalibrations. Long-term calibration stability might then be achieved using either a scene-based non-uniformity correction approach, or with periodic repointing for off-source background estimation and subtraction. Either approach requires dithering of the field of view, by sub-pixel amounts for the first method, or by large off-source motions outside the 0.38 milliradian FOV for the latter method. We report on the results of investigations along both these lines.
NASA Astrophysics Data System (ADS)
Liu, Chengwei; Sui, Xiubao; Gu, Guohua; Chen, Qian
2018-02-01
For the uncooled long-wave infrared (LWIR) camera, the infrared (IR) irradiation the focal plane array (FPA) receives is a crucial factor that affects the image quality. Ambient temperature fluctuation as well as system power consumption can result in changes of FPA temperature and radiation characteristics inside the IR camera; these will further degrade the imaging performance. In this paper, we present a novel shutterless non-uniformity correction method to compensate for non-uniformity derived from the variation of ambient temperature. Our method combines a calibration-based method and the properties of a scene-based method to obtain correction parameters at different ambient temperature conditions, so that the IR camera performance can be less influenced by ambient temperature fluctuation or system power consumption. The calibration process is carried out in a temperature chamber with slowly changing ambient temperature and a black body as uniform radiation source. Enough uniform images are captured and the gain coefficients are calculated during this period. Then in practical application, the offset parameters are calculated via the least squares method based on the gain coefficients, the captured uniform images and the actual scene. Thus we can get a corrected output through the gain coefficients and offset parameters. The performance of our proposed method is evaluated on realistic IR images and compared with two existing methods. The images we used in experiments are obtained by a 384× 288 pixels uncooled LWIR camera. Results show that our proposed method can adaptively update correction parameters as the actual target scene changes and is more stable to temperature fluctuation than the other two methods.
Platelet activity in Chinese obese adolescents with and without insulin resistance.
Lu, Huimin; Lei, Shundong; Zhao, Jiuming; Chen, Ni
2014-01-01
To investigate the platelet activity in Chinese obese adolescents with and without insulin resistance. A cross-sectional study was performed in 159 obese Chinese adolescents to investigate their platelet activity using anthropometrics and biochemical parameters, oral glucose tolerance test and platelet testing. An index of insulin sensitivity, homeostasis model assessment of insulin resistance (HOMA-IR), and plasma fibrinogen, prothrombin fragment 1.2 (PT 1.2), fibrinopeptide A (FPA) and the levels of aggregation to collagen 1 μg/ml, adenosine diphosphate (ADP) 10 μmol/L and arachidonic acid (AA) 0.5 mmol/L were measured. Obese adolescents with insulin resistance had significantly higher HOMA-IR, glucose response curve (AUC), insulin AUC, PT 1.2, FPA and fibrinogen and aggregation (to collagen 1 μg/ml, ADP 10 μmol/L and AA 0.5 mmol/L) comparison with obese adolescents without insulin resistance (P < 0.05). Moreover, a positive correlation was found between both aggregation (to collagen, ADP and AA) and HOMA-IR (ρ = 0.716; P < 0.01, ρ = 0.682; P < 0.01 and ρ = 0.699; P < 0.01, respectively), glucose AUC (ρ = 0.479; P < 0.01, ρ = 0.416; P < 0.01 and ρ = 0.458; P < 0.01, respectively) and insulin AUC (ρ = 0.585; P < 0.01, ρ = 0.511; P < 0.01 and ρ = 0.576; P < 0.01, respectively) in obese adolescents with insulin resistance. Insulin resistance is a major determinant of platelet activation in Chinese obese adolescents.
Kim, Paul Y.; Vu, Trang T.; Leslie, Beverly A.; Stafford, Alan R.; Fredenburgh, James C.; Weitz, Jeffrey I.
2014-01-01
Fibrin (Fn) clots formed from γ′-fibrinogen (γ′-Fg), a variant with an elongated γ-chain, are resistant to lysis when compared with clots formed from the predominant γA-Fg, a finding previously attributed to differences in clot structure due to delayed thrombin-mediated fibrinopeptide (FP) B release or impaired cross-linking by factor XIIIa. We investigated whether slower lysis of γ′-Fn reflects delayed plasminogen (Pg) binding and/or activation by tissue plasminogen activator (tPA), reduced plasmin-mediated proteolysis of γ′-Fn, and/or altered cross-linking. Clots formed from γ′-Fg lysed more slowly than those formed from γA-Fg when lysis was initiated with tPA/Pg when FPA and FPB were both released, but not when lysis was initiated with plasmin, or when only FPA was released. Pg bound to γ′-Fn with an association rate constant 22% lower than that to γA-Fn, and the lag time for initiation of Pg activation by tPA was longer with γ′-Fn than with γA-Fn. Once initiated, however, Pg activation kinetics were similar. Factor XIIIa had similar effects on clots formed from both Fg isoforms. Therefore, slower lysis of γ′-Fn clots reflects delayed FPB release, which results in delayed binding and activation of Pg. When clots were formed from Fg mixtures containing more than 20% γ′-Fg, the upper limit of the normal level, the delay in lysis was magnified. These data suggest that circulating levels of γ′-Fg modulate the susceptibility of clots to lysis by slowing Pg activation by tPA and provide another example of the intimate connections between coagulation and fibrinolysis. PMID:25128532
Design and performance of single photon APD focal plane arrays for 3-D LADAR imaging
NASA Astrophysics Data System (ADS)
Itzler, Mark A.; Entwistle, Mark; Owens, Mark; Patel, Ketan; Jiang, Xudong; Slomkowski, Krystyna; Rangwala, Sabbir; Zalud, Peter F.; Senko, Tom; Tower, John; Ferraro, Joseph
2010-08-01
×We describe the design, fabrication, and performance of focal plane arrays (FPAs) for use in 3-D LADAR imaging applications requiring single photon sensitivity. These 32 × 32 FPAs provide high-efficiency single photon sensitivity for three-dimensional LADAR imaging applications at 1064 nm. Our GmAPD arrays are designed using a planarpassivated avalanche photodiode device platform with buried p-n junctions that has demonstrated excellent performance uniformity, operational stability, and long-term reliability. The core of the FPA is a chip stack formed by hybridizing the GmAPD photodiode array to a custom CMOS read-out integrated circuit (ROIC) and attaching a precision-aligned GaP microlens array (MLA) to the back-illuminated detector array. Each ROIC pixel includes an active quenching circuit governing Geiger-mode operation of the corresponding avalanche photodiode pixel as well as a pseudo-random counter to capture per-pixel time-of-flight timestamps in each frame. The FPA has been designed to operate at frame rates as high as 186 kHz for 2 μs range gates. Effective single photon detection efficiencies as high as 40% (including all optical transmission and MLA losses) are achieved for dark count rates below 20 kHz. For these planar-geometry diffused-junction GmAPDs, isolation trenches are used to reduce crosstalk due to hot carrier luminescence effects during avalanche events, and we present details of the crosstalk performance for different operating conditions. Direct measurement of temporal probability distribution functions due to cumulative timing uncertainties of the GmAPDs and ROIC circuitry has demonstrated a FWHM timing jitter as low as 265 ps (standard deviation is ~100 ps).
Detection of hidden objects using a real-time 3-D millimeter-wave imaging system
NASA Astrophysics Data System (ADS)
Rozban, Daniel; Aharon, Avihai; Levanon, Assaf; Abramovich, Amir; Yitzhaky, Yitzhak; Kopeika, N. S.
2014-10-01
Millimeter (mm)and sub-mm wavelengths or terahertz (THz) band have several properties that motivate their use in imaging for security applications such as recognition of hidden objects, dangerous materials, aerosols, imaging through walls as in hostage situations, and also in bad weather conditions. There is no known ionization hazard for biological tissue, and atmospheric degradation of THz radiation is relatively low for practical imaging distances. We recently developed a new technology for the detection of THz radiation. This technology is based on very inexpensive plasma neon indicator lamps, also known as Glow Discharge Detector (GDD), that can be used as very sensitive THz radiation detectors. Using them, we designed and constructed a Focal Plane Array (FPA) and obtained recognizable2-dimensional THz images of both dielectric and metallic objects. Using THz wave it is shown here that even concealed weapons made of dielectric material can be detected. An example is an image of a knife concealed inside a leather bag and also under heavy clothing. Three-dimensional imaging using radar methods can enhance those images since it can allow the isolation of the concealed objects from the body and environmental clutter such as nearby furniture or other people. The GDDs enable direct heterodyning between the electric field of the target signal and the reference signal eliminating the requirement for expensive mixers, sources, and Low Noise Amplifiers (LNAs).We expanded the ability of the FPA so that we are able to obtain recognizable 2-dimensional THz images in real time. We show here that the THz detection of objects in three dimensions, using FMCW principles is also applicable in real time. This imaging system is also shown here to be capable of imaging objects from distances allowing standoff detection of suspicious objects and humans from large distances.
Advocacy in the Western Hemisphere Region: some FPA success stories.
Andrews, D J
1996-01-01
The International Planned Parenthood Federation's Vision 2000 Strategic Plan has emphasized advocacy and the training of family planning associations (FPAs) in the Western Hemisphere region. During the summer of 1995 training programs in advocacy leadership management were sponsored for six FPAs in the Bahamas, Suriname, Belize, Colombia, Honduras, and Brazil. At the Western Hemisphere Regional Council Meeting in September 1995 awards were presented to FPAs for media outstanding projects. These FPAs used outreach to the community to promote the goals of Vision 2000. The Bahamas FPA won the Rosa Cisneros Award for articles published in a magazine that is distributed in primary and secondary schools and deals with the activities, achievements, and opinions of students. Issues include: love, relationships, responsibility, and teen pregnancy. A weekly television talk show also addresses the issues facing youth including education, music, community work, sexuality, pregnancy, and the relationship between teenagers and adults. The Family Planning Association of Honduras was also nominated for the award for a radio show on the health of mothers and children, the problems of adolescents, and FP. The newspaper Tiempo received the award for feature articles on social issues and FP. In 1994 the Association distributed thousands of booklets on contraceptives as well as fliers on vasectomy, female sterilization, oral contraceptives, IUDs, condoms, responsible parenthood, high-risk pregnancy, vaginal cytology, and cervical cancer. Similar posters were placed in hospitals and health centers, in 1997 FP posts, and 400 commercial outlets. The Family Planning Association of Suriname also carried out an impressive advocacy program during the period of 1968-93 with the goals of establishing a balance between population growth and the available resources to achieve well-being with regard to education, health care, nutrition, and housing.
Cardiovascular responses to railway noise during sleep in young and middle-aged adults.
Tassi, Patricia; Saremi, Mahnaz; Schimchowitsch, Sarah; Eschenlauer, Arnaud; Rohmer, Odile; Muzet, Alain
2010-03-01
The aim of this study was to investigate the effects of nocturnal railway noise on cardiovascular reactivity in young (25.8 +/- 2.6 years) and middle-aged (52.2 +/- 2.5 years) adults during sleep. Thirty-eight subjects slept three nights in the laboratory at 1-week interval. They were exposed to 48 randomized pass-bys of Freight, Passenger and Automotive trains either at an 8-h equivalent sound level of 40 dBA (Moderate) and 50 dBA (High) or at a silent Control night. Heart rate response (HRR), heart response amplitude (HRA), heart response latency (HRL) and finger pulse response (FPR), finger pulse amplitude (FPA) and finger pulse latency (FPL) were recorded to measure cardiovascular reactivity after each noise onset and for time-matched pseudo-noises in the control condition. Results show that Freight trains produced the highest cardiac response (increased HRR, HRA and HRL) compared to Passenger and Automotive. But the vascular response was similar whatever the type of train. Juniors exhibited an increased HRR and HRA as compared to seniors, but there was no age difference on vasoconstriction, except a shorter FPL in seniors. Noise level produced dose-dependent effects on all the cardiovascular indices. Sleep stage at noise occurrence was ineffective for cardiac response, but FPA was reduced when noise occurred during REM sleep. In conclusion, our study is in favor of an important impact of nocturnal railway noise on the cardiovascular system of sleeping subjects. In the limit of the samples studied, Freight trains are the most harmful, probably more because of their special length (duration) than because of their speed (rise time).
Epizootiology of Brucella infection in Australian fur seals.
Lynch, Michael; Duignan, Pádraig J; Taylor, Trevor; Nielsen, Ole; Kirkwood, Roger; Gibbens, John; Arnould, John P Y
2011-04-01
Novel members of the bacterial genus Brucella have recently emerged as pathogens of various marine mammal species and as potential zoonotic agents. We investigated the epizootiology of Brucella infection in Australian fur seals (Arctocephalus pusillus doriferus) by establishing demographic and temporal variations in antibody prevalence, attempting isolation of the causative agent, and determining whether this potential pathogen is involved in frequent abortions observed in this pinniped species. Two competitive enzyme-linked immunosorbent assays (cELISAs), an indirect ELISA, and a fluorescence polarization assay (FPA) were used to test sera for Brucella antibodies. The FPA and cELISA proved suitable for use in this species. Significant differences in antibody prevalence were found between age classes of seals sampled between 2007 and 2009 at one colony. Pups sampled at this site (n=134) were negative for Brucella antibodies by all serologic tests but 17 of 45 (38%) of juveniles were antibody-positive. Antibody prevalence in adult females was significantly higher than in juveniles (P=0.044). Antibody prevalence for adult females between 2003 and 2009 varied significantly over time (P=0.011), and for individuals sampled between 2003 and 2005, the likelihood of pregnancy was greater in individuals positive for Brucella antibodies (P=0.034). Inflammatory lesions suggestive of infectious agents were found in 14 of 39 aborted Australian fur seal pups, but pathologic changes were not uniformly consistent for Brucella infection. Culture and PCR investigations on fetal tissues were negative for Brucella. Culture and PCR on selected fresh or frozen tissues from 36 juvenile and adult animals were also negative. We suspect that the prevalence of active infection with Brucella in Australian fur seals is low relative to antibody prevalence.
Gated IR imaging with 128 × 128 HgCdTe electron avalanche photodiode FPA
NASA Astrophysics Data System (ADS)
Beck, Jeff; Woodall, Milton; Scritchfield, Richard; Ohlson, Martha; Wood, Lewis; Mitra, Pradip; Robinson, Jim
2007-04-01
The next generation of IR sensor systems will include active imaging capabilities. One example of such a system is a gated-active/passive system. The gated-active/passive system promises long-range target detection and identification. A detector that is capable of both active and passive modes of operation opens up the possibility of a self-aligned system that uses a single focal plane. The detector would need to be sensitive in the 3-5 μm band for passive mode operation. In the active mode, the detector would need to be sensitive in eye-safe range, e.g. 1.55 μm, and have internal gain to achieve the required system sensitivity. The MWIR HgCdTe electron injection avalanche photodiode (e-APD) not only provides state-of-the-art 3-5 μm spectral sensitivity, but also high avalanche photodiode gain without minimal excess noise. Gains of greater than 1000 have been measured in MWIR e-APDs with a gain independent excess noise factor of 1.3. This paper reports the application of the mid-wave HgCdTe e-APD for near-IR gated-active/passive imaging. Specifically a 128x128 FPA composed of 40 μm pitch, 4.2 μm to 5 μm cutoff, APD detectors with a custom readout integrated circuit was designed, fabricated, and tested. Median gains as high as 946 at 11 V bias with noise equivalent inputs as low as 0.4 photon were measured at 80 K. A gated imaging demonstration system was designed and built using commercially available parts. High resolution gated imagery out to 9 km was obtained with this system that demonstrated predicted MTF, precision gating, and sub 10 photon sensitivity.
Advances in hyperspectral LWIR pushbroom imagers
NASA Astrophysics Data System (ADS)
Holma, Hannu; Mattila, Antti-Jussi; Hyvärinen, Timo; Weatherbee, Oliver
2011-06-01
Two long-wave infrared (LWIR) hyperspectral imagers have been under extensive development. The first one utilizes a microbolometer focal plane array (FPA) and the second one is based on an Mercury Cadmium Telluride (MCT) FPA. Both imagers employ a pushbroom imaging spectrograph with a transmission grating and on-axis optics. The main target has been to develop high performance instruments with good image quality and compact size for various industrial and remote sensing application requirements. A big challenge in realizing these goals without considerable cooling of the whole instrument is to control the instrument radiation. The challenge is much bigger in a hyperspectral instrument than in a broadband camera, because the optical signal from the target is spread spectrally, but the instrument radiation is not dispersed. Without any suppression, the instrument radiation can overwhelm the radiation from the target even by 1000 times. The means to handle the instrument radiation in the MCT imager include precise instrument temperature stabilization (but not cooling), efficient optical background suppression and the use of background-monitoring-on-chip (BMC) method. This approach has made possible the implementation of a high performance, extremely compact spectral imager in the 7.7 to 12.4 μm spectral range. The imager performance with 84 spectral bands and 384 spatial pixels has been experimentally verified and an excellent NESR of 14 mW/(m2srμm) at 10 μm wavelength with a 300 K target has been achieved. This results in SNR of more than 700. The LWIR imager based on a microbolometer detector array, first time introduced in 2009, has been upgraded. The sensitivity of the imager has improved drastically by a factor of 3 and SNR by about 15 %. It provides a rugged hyperspectral camera for chemical imaging applications in reflection mode in laboratory and industry.
Development and Production of Array Barrier Detectors at SCD
NASA Astrophysics Data System (ADS)
Klipstein, P. C.; Avnon, E.; Benny, Y.; Berkowicz, E.; Cohen, Y.; Dobromislin, R.; Fraenkel, R.; Gershon, G.; Glozman, A.; Hojman, E.; Ilan, E.; Karni, Y.; Klin, O.; Kodriano, Y.; Krasovitsky, L.; Langof, L.; Lukomsky, I.; Nevo, I.; Nitzani, M.; Pivnik, I.; Rappaport, N.; Rosenberg, O.; Shtrichman, I.; Shkedy, L.; Snapi, N.; Talmor, R.; Tessler, R.; Weiss, E.; Tuito, A.
2017-09-01
XB n or XB p barrier detectors exhibit diffusion-limited dark currents comparable with mercury cadmium telluride Rule-07 and high quantum efficiencies. In 2011, SemiConductor Devices (SCD) introduced "HOT Pelican D", a 640 × 512/15- μm pitch InAsSb/AlSbAs XB n mid-wave infrared (MWIR) detector with a 4.2- μm cut-off and an operating temperature of ˜150 K. Its low power (˜3 W), high pixel operability (>99.5%) and long mean time to failure make HOT Pelican D a highly reliable integrated detector-cooler product with a low size, weight and power. More recently, "HOT Hercules" was launched with a 1280 × 1024/15- μm format and similar advantages. A 3-megapixel, 10- μm pitch version ("HOT Blackbird") is currently completing development. For long-wave infrared applications, SCD's 640 × 512/15- μm pitch "Pelican-D LW" XB p type II superlattice (T2SL) detector has a ˜9.3- μm cut-off wavelength. The detector contains InAs/GaSb and InAs/AlSb T2SLs, and is fabricated into focal plane array (FPA) detectors using standard production processes including hybridization to a digital silicon read-out integrated circuit (ROIC), glue underfill and substrate thinning. The ROIC has been designed so that the complete detector closely follows the interfaces of SCD's MWIR Pelican-D detector family. The Pelican-D LW FPA has a quantum efficiency of ˜50%, and operates at 77 K with a pixel operability of >99% and noise equivalent temperature difference of 13 mK at 30 Hz and F/2.7.
Saglam, Yavuz; Ekin Akalan, N; Temelli, Yener; Kuchimov, Shavkat
2016-02-01
Poor motor control and delayed thumb function and a delay in walking are the main factors which retard the natural decrease of the femoral anteversion (FA) with age. In addition, cerebral palsy (CP) patients usually have muscular imbalance around the hip as well as muscle contractures, both of which are main factors accounting for the increased FA which is commonly present in CP patients. The purpose of this retrospective study was to analyze the mid-term results of femoral derotational osteotomy (FDO) on the clinical findings, temporospatial and kinematic parameters of gait in children with CP. We performed a retrospective review of all patients diagnosed with CP and increased FA who were treated with FDO with multi-level soft tissue surgeries at a single institution between 1992 and 2011. FA assessment was done in the prone position, and internal (IR) and external rotation (ER) of the hip was measured in the absence of pelvis rotation. Surgical procedures were performed on the basis of both clinical findings and video analysis. Clinical findings, Edinburgh Visual Gait Scores (EVGS) and results from three-dimensional gait analysis were analyzed preoperatively and last follow-up. A total of 93 patients with 175 affected extremities were included in this review. Mean age was 6.2 ± 3.1 (standard deviation) at initial surgery. The average length of the follow-up period was 6.3 ± 3.7 years. At the last follow-up, the postoperative hip IR had significantly decreased (73.9° vs. 46.2°; p < 0.0001), the hip ER had significantly improved (23.8° vs. 37°; p < 0.0001) and the popliteal angle had significantly decreased (64.2° vs. 55.8°; p < 0.0001). The total EVGS showed significant improvement after FDO (35.2 ± 6.4 vs. 22.5 ± 6.1; p < 0.001). Computed gait analysis showed significant improvement in the foot progression angle (FPA; 8.1° vs. -16.9°; p = 0.005) and hip rotation (-13.9° vs. 5.7°; p = 0.01) at the last follow-up. Stance time was improved (60.2 vs. 65.1 %; p = 0.02) and swing time was decreased (39.9 vs. 35.2 %; p = 0.03). Double support time and cadence were both decreased (p = 0.032 and p = 0.01). Our data suggest that the FDO is an appropriate treatment strategy for the correction of FA and associated in-toeing gait in children with CP. Improvements in clinical and kinematic parameters were observed in both groups after FDO with multi-level soft tissue release. The most prominent effects of FDO were on transverse plane hip rotation and FPA.
Lead salt room-temperature MWIR FPA
NASA Astrophysics Data System (ADS)
Murphy, Paul F.; Jost, Steven R.; Barrett, John L.; Reese, Dan; Winn, Michael L.
2001-10-01
The development of low-cost uncooled thermal LWIR FPAs is resulting in the emergence of a new generation of infrared sensors for applications where affordability is the prerequisite for volume production. Both ferroelectric detector arrays and silicon-based microbolometers are finding numerous applications from gun sights to automotive FLIRs. There would be significant interest in a similar uncooled offering in the MWIR, but to date, thermal detectors have lacked sufficient sensitivity. The existing uncooled MWIR photon detector technology, based on polycrystalline lead salts, has been relegated to single-element detectors and relatively small linear arrays due to the high dark current and the stigma of being a 50-year-old technology.
Plasmid acquisition in microgravity
NASA Technical Reports Server (NTRS)
Juergensmeyer, Margaret A.; Juergensmeyer, Elizabeth A.; Guikema, James A.
1995-01-01
In microgravity, bacteria often show an increased resistance to antibiotics. Bacteria can develop resistance to an antibiotic after transformation, the acquisition of DNA, usually in the form of a plasmid containing a gene for resistance to one or more antibiotics. In order to study the capacity of bacteria to become resistant to antibiotics in microgravity, we have modified the standard protocol for transformation of Escherichia coli for use in the NASA-flight-certified hardware package, The Fluid Processing Apparatus (FPA). Here we report on the ability of E. coli to remain competent for long periods of time at temperatures that are readily available on the Space Shuttle, and present some preliminary flight results.
QWIP technology for both military and civilian applications
NASA Astrophysics Data System (ADS)
Gunapala, Sarath D.; Kukkonen, Carl A.; Sirangelo, Mark N.; McQuiston, Barbara K.; Chehayeb, Riad; Kaufmann, M.
2001-10-01
Advanced thermal imaging infrared cameras have been a cost effective and reliable method to obtain the temperature of objects. Quantum Well Infrared Photodetector (QWIP) based thermal imaging systems have advanced the state-of-the-art and are the most sensitive commercially available thermal systems. QWIP Technologies LLC, under exclusive agreement with Caltech University, is currently manufacturing the QWIP-ChipTM, a 320 X 256 element, bound-to-quasibound QWIP FPA. The camera performance falls within the long-wave IR band, spectrally peaked at 8.5 μm. The camera is equipped with a 32-bit floating-point digital signal processor combined with multi- tasking software, delivering a digital acquisition resolution of 12-bits using nominal power consumption of less than 50 Watts. With a variety of video interface options, remote control capability via an RS-232 connection, and an integrated control driver circuit to support motorized zoom and focus- compatible lenses, this camera design has excellent application in both the military and commercial sector. In the area of remote sensing, high-performance QWIP systems can be used for high-resolution, target recognition as part of a new system of airborne platforms (including UAVs). Such systems also have direct application in law enforcement, surveillance, industrial monitoring and road hazard detection systems. This presentation will cover the current performance of the commercial QWIP cameras, conceptual platform systems and advanced image processing for use in both military remote sensing and civilian applications currently being developed in road hazard monitoring.
The interface character distribution of cold-rolled and annealed duplex stainless steel
DOE Office of Scientific and Technical Information (OSTI.GOV)
Fang, Xiaoying, E-mail: fxy@sdut.edu.cn
The interface character distributions (ICDs) of cold-rolled and annealed duplex stainless steel specimens, previously solid-solution-heated (SHT) at 1573 K and 1323 K, are investigated using electron backscatter diffraction (EBSD) and five-parameter analysis (FPA). For the δ-ferrite phase, high concentrations of low angle grain boundaries (LAGBs) are developed, and the boundary planes are predominantly oriented on (111). High angle grain boundaries (HAGBs) with misorientations ranging from 50{sup o} to 60° are mostly pure tilt boundaries, and the boundary planes are primarily located on (112). For the austenite phase, very high density of coherent twin boundaries are introduced, implying that the boundarymore » planes are exactly oriented on (111). The phase boundary character distribution (PBPD) appears to be connected with the K-S and N-W orientation relationships (ORs) terminating on (110) {sub F}‖(111) {sub A} and (110){sub F}‖(hkl){sub A}, respectively. - Highlights: •Five-parameter analysis was used to determine interface character distribution. •ICD results of statistical meaning were achieved. •Initial microstructure has a significant effect on ICD. •Low and high angle GBs in δ phase prefer in (111) and (112) planes, respectively. •K-S phase boundaries terminate on (110){sub F}‖(111){sub A} while N-W ones on (110){sub F}‖(hkl){sub A}.« less
NASA Astrophysics Data System (ADS)
Vainer, Boris G.; Morozov, Vitaly V.
A peculiar branch of biophotonics is a measurement, visualisation and quantitative analysis of infrared (IR) radiation emitted from living object surfaces. Focal plane array (FPA)-based IR cameras make it possible to realize in medicine the so called interventional infrared thermal diagnostics. An integrated technique aimed at the advancement of this new approach in biomedical science and practice is described in the paper. The assembled system includes a high-performance short-wave (2.45-3.05 μm) or long-wave (8-14 μm) IR camera, two laser Doppler flowmeters (LDF) and additional equipment and complementary facilities implementing the monitoring of human cardiovascular status. All these means operate synchronously. It is first ascertained the relationship between infrared thermography (IRT) and LDF data in humans in regard to their systemic cardiovascular reactivity. Blood supply real-time dynamics in a narcotized patient is first visualized and quantitatively represented during surgery in order to observe how the general hyperoxia influences thermoregulatory mechanisms; an abrupt increase in temperature of the upper limb is observed using IRT. It is outlined that the IRT-based integrated technique may act as a take-off runway leading to elaboration of informative new methods directly applicable to medicine and biomedical sciences.
VIIRS day-night band gain and offset determination and performance
NASA Astrophysics Data System (ADS)
Geis, J.; Florio, C.; Moyer, D.; Rausch, K.; De Luccia, F. J.
2012-09-01
On October 28th, 2011, the Visible-Infrared Imaging Radiometer Suite (VIIRS) was launched on-board the Suomi National Polar-orbiting Partnership (NPP) spacecraft. The instrument has 22 spectral bands: 14 reflective solar bands (RSB), 7 thermal emissive bands (TEB), and a Day Night Band (DNB). The DNB is a panchromatic, solar reflective band that provides visible through near infrared (IR) imagery of earth scenes with radiances spanning 7 orders of magnitude. In order to function over this large dynamic range, the DNB employs a focal plane array (FPA) consisting of three gain stages: the low gain stage (LGS), the medium gain stage (MGS), and the high gain stage (HGS). The final product generated from a DNB raw data record (RDR) is a radiance sensor data record (SDR). Generation of the SDR requires accurate knowledge of the dark offsets and gain coefficients for each DNB stage. These are measured on-orbit and stored in lookup tables (LUT) that are used during ground processing. This paper will discuss the details of the offset and gain measurement, data analysis methodologies, the operational LUT update process, and results to date including a first look at trending of these parameters over the early life of the instrument.
Recursive algorithms for bias and gain nonuniformity correction in infrared videos.
Pipa, Daniel R; da Silva, Eduardo A B; Pagliari, Carla L; Diniz, Paulo S R
2012-12-01
Infrared focal-plane array (IRFPA) detectors suffer from fixed-pattern noise (FPN) that degrades image quality, which is also known as spatial nonuniformity. FPN is still a serious problem, despite recent advances in IRFPA technology. This paper proposes new scene-based correction algorithms for continuous compensation of bias and gain nonuniformity in FPA sensors. The proposed schemes use recursive least-square and affine projection techniques that jointly compensate for both the bias and gain of each image pixel, presenting rapid convergence and robustness to noise. The synthetic and real IRFPA videos experimentally show that the proposed solutions are competitive with the state-of-the-art in FPN reduction, by presenting recovered images with higher fidelity.
Software Life Cycle Management Workshop (2nd) August 21-22, 1978, Atlanta, Georgia.
1978-08-01
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Shinotsuka, H.; Da, B.; Tanuma, S.; Yoshikawa, H.; Powell, C. J.; Penn, D. R.
2017-01-01
We calculated electron inelastic mean free paths (IMFPs) for liquid water from its optical energy-loss function (ELF) for electron energies from 50 eV to 30 keV. These calculations were made with the relativistic full Penn algorithm (FPA) that has been used for previous IMFP and electron stopping-power calculations for many elemental solids. We also calculated IMFPs of water with three additional algorithms: the relativistic single-pole approximation (SPA), the relativistic simplified SPA, and the relativistic extended Mermin method. These calculations were made using the same optical ELF in order to assess any differences of the IMFPs arising from choice of the algorithm. We found good agreement among the IMFPs from the four algorithms for energies over 300 eV. For energies less than 100 eV, however, large differences became apparent. IMFPs from the relativistic TPP-2M equation for predicting IMFPs were in good agreement with IMFPs from the four algorithms for energies between 300 eV and 30 keV but there was poorer agreement for lower energies. We calculated values of the static structure factor as a function of momentum transfer from the FPA. The resulting values were in good agreement with results from first-principles calculations and with inelastic X-ray scattering spectroscopy experiments. We made comparisons of our IMFPs with earlier calculations from authors who had used different algorithms and different ELF data sets. IMFP differences could then be analyzed in terms of the algorithms and the data sets. Finally, we compared our IMFPs with measurements of IMFPs and of a related quantity, the effective attenuation length (EAL). There were large variations in the measured IMFPs and EALs (as well as their dependence on electron energy). Further measurements are therefore required to establish consistent data sets and for more detailed comparisons with calculated IMFPs. PMID:28751796
Shinotsuka, H; Da, B; Tanuma, S; Yoshikawa, H; Powell, C J; Penn, D R
2017-04-01
We calculated electron inelastic mean free paths (IMFPs) for liquid water from its optical energy-loss function (ELF) for electron energies from 50 eV to 30 keV. These calculations were made with the relativistic full Penn algorithm (FPA) that has been used for previous IMFP and electron stopping-power calculations for many elemental solids. We also calculated IMFPs of water with three additional algorithms: the relativistic single-pole approximation (SPA), the relativistic simplified SPA, and the relativistic extended Mermin method. These calculations were made using the same optical ELF in order to assess any differences of the IMFPs arising from choice of the algorithm. We found good agreement among the IMFPs from the four algorithms for energies over 300 eV. For energies less than 100 eV, however, large differences became apparent. IMFPs from the relativistic TPP-2M equation for predicting IMFPs were in good agreement with IMFPs from the four algorithms for energies between 300 eV and 30 keV but there was poorer agreement for lower energies. We calculated values of the static structure factor as a function of momentum transfer from the FPA. The resulting values were in good agreement with results from first-principles calculations and with inelastic X-ray scattering spectroscopy experiments. We made comparisons of our IMFPs with earlier calculations from authors who had used different algorithms and different ELF data sets. IMFP differences could then be analyzed in terms of the algorithms and the data sets. Finally, we compared our IMFPs with measurements of IMFPs and of a related quantity, the effective attenuation length (EAL). There were large variations in the measured IMFPs and EALs (as well as their dependence on electron energy). Further measurements are therefore required to establish consistent data sets and for more detailed comparisons with calculated IMFPs.
NASA Astrophysics Data System (ADS)
Dobado, Antonio; Guo, Feng-Kun; Llanes-Estrada, Felipe J.
2015-12-01
We are exploring a generic strongly-interacting Electroweak Symmetry Breaking Sector (EWSBS) with the low-energy effective field theory for the four experimentally known particles (W±L, ZL, h) and its dispersion-relation based unitary extension. In this contribution we provide simple estimates for the production cross-section of pairs of the EWSBS bosons and their resonances at proton-proton colliders as well as in a future e-e+ (or potentially a μ-μ+) collider with a typical few-TeV energy. We examine the simplest production mechanisms, tree-level production through a W (dominant when quantum numbers allow) and the simple effective boson approximation (in which the electroweak bosons are considered as collinear partons of the colliding fermions). We exemplify with custodial isovector and isotensor resonances at 2 TeV, the energy currently being discussed because of a slight excess in the ATLAS 2-jet data. We find it hard, though not unthinkable, to ascribe this excess to one of these WLWL rescattering resonances. An isovector resonance could be produced at a rate smaller than, but close to earlier CMS exclusion bounds, depending on the parameters of the effective theory. The ZZ excess is then problematic and requires additional physics (such as an additional scalar resonance). The isotensor one (that would describe all charge combinations) has smaller cross-section. Supported by the Spanish Excellence Network on Hadronic Physics FIS2014-57026-REDT, by Spanish Grants Universidad Complutense UCM:910309 and Ministerio de Economia y Competitividad MINECO:FPA2011-27853-C02-01, MINECO:FPA2014-53375-C2-1-P, by the Deutsche Forschungsgemeinschaft and National Natural Science Foundation of China through Funds Provided to the Sino-German CRC 110 “Symmetries and the Emergence of Structure in QCD” (NSFC Grant No. 11261130311) and by NSFC (Grant No. 11165005)
High density Schottky barrier IRCCD sensors for SWIR applications at intermediate temperature
NASA Technical Reports Server (NTRS)
Elabd, H.; Villani, T. S.; Tower, J. R.
1982-01-01
Monolithic 32 x 64 and 64 x 1:128 palladium silicide (Pd2Si) interline transfer infrared charge coupled devices (IRCCDs) sensitive in the 1 to 3.5 micron spectral band were developed. This silicon imager exhibits a low response nonuniformity of typically 0.2 to 1.6% rms, and was operated in the temperature range between 40 to 140 K. Spectral response measurements of test Pd2Si p-type Si devices yield quantum efficiencies of 7.9% at 1.25 microns, 5.6% at 1.65 microns 2.2% at 2.22 microns. Improvement in quantum efficiency is expected by optimizing the different structural parameters of the Pd2Si detectors. The spectral response of the Pd2Si detectors fit a modified Fowler emission model. The measured photo-electric barrier height for the Pd2Si detectors is 0.34 eV and the measured quantum efficiency coefficient, C1, is 19%/eV. The dark current level of Pd2Si Schottky barrier focal plane arrays (FPAs) is sufficiently low to enable operation at intermediate temperatures at TV frame rates. Typical dark current level measured at 120 K on the FPA is 2 nA/sq cm. The operating temperature of the Pd2Si FPA is compatible with passive cooler performance. In addition, high density Pd2Si Schottky barrier FPAs are manufactured with high yield and therefore represent an economical approach to short wavelength IR imaging. A Pd2Si Schottky barrier image sensor for push-broom multispectral imaging in the 1.25, 1.65, and 2.22 micron bands is being studied. The sensor will have two line arrays (dual band capability) of 512 detectors each, with 30 micron center-to-center detector spacing. The device will be suitable for chip-to-chip abutment, thus providing the capability to produce large, multiple chip focal planes with contiguous, in-line sensors.
NASA Astrophysics Data System (ADS)
Vainer, Boris G.
2005-12-01
This review gives an overview of focal plane array (FPA)-based infrared (IR) thermography as a powerful research method in the field of physiology and medicine. Comparison of the gained results with the data previously obtained by other authors with other research tools is given. Outer thermoregulatory manifestations displayed by the human organism subjected to whole-body heating (sauna bath) and physical loads (exercise bicycling) are quantitatively analysed. Some details of human body emotional sweating (psycho-physiological effect) are reported. Particular attention is paid to studying active sweat glands as individual objects. All experimental data were obtained with the help of a high-sensitivity (0.03 °C) fast 128 × 128 InAs IR detector-based thermal imaging system operating in the short-wave spectral region (2.5 to 3 µm) and perfectly suiting medical purposes. It is shown that IR thermography makes it possible to overcome limitations inherent to contact measuring means that were traditionally used before in thermal studies. It is also shown that heterogeneous thermograms displayed by organisms with disturbed inner equilibrium can be quantitatively analysed in terms of statistical parameters of related surface-temperature histograms, such as the mean temperature and the standard deviation of temperature (SDT). The increase and the decrease in SDT turned out to be typical of prolonged physical load and subsequent relaxation, and of external whole-body heating, respectively. Explanation of this result based on a hypothesis advanced within the context of the doctrine of human-organism evolution is given. Skin-temperature distribution function accompanying the relaxed organism in normality was found to closely resemble normal-distribution function. Symmetry break down and variation of the shape of this characteristic may serve as an indicator of homeostasis shift and can be used as a quantitative criterion for the latter. A new phenomenon, stable punctate hidrosis, is discovered and described. The term sweatology is introduced to refer to the discussed specific research area in biomedical science.
Uncooled detectors optimized for unattended applications
NASA Astrophysics Data System (ADS)
Malkinson, E.; Fraenkel, A.; Mizrahi, U.; Ben-Ezra, M.; Bikov, L.; Adin, A.; Zabar, Y.; Seter, D.; Kopolovich, Z.
2005-10-01
SCD has recently presented an uncooled detector product line based on the high-end VOx bolometer technology. The first FPA launched, named BIRD - short for Bolometer Infra Red Detector, is a 384x288 (or 320x240) configurable format with 25μm pitch. Typical NETD values for these FPAs range at 50mK with an F/1 aperture and 60 Hz frame rate. These detectors also exhibit a relatively fast thermal time constant of approximately 10 msec, as reported previously. In this paper, the special features of BIRD optimized for unattended sensor applications are presented and discussed. Unattended surveillance using sensors on unattended aerial vehicles (UAV's) or micro air vehicles (MAV's) , unattended ground vehicles (UGV's) or unattended ground sensor (UGS) are growing applications for uncooled detectors. This is due to their low power consumption, low weight, negligible acoustic noise and reduced price. On the other hand, uncooled detectors are vulnerable to ambient drift. Even minor temperature fluctuations are manifested as fixed pattern noise (FPN). As a result, frequent, shutter operation must be applied, with the risk of blocking the scenery in critical time frames and loosing information for various scenarios. In order to increase the time span between shutter operations, SCD has incorporated various features within the FPA and supporting algorithms. This paper will discuss these features and present some illustrative examples. Minimum power consumption is another critical issue for unattended applications. SCD has addressed this topic by introducing the "Power Save" concept. For very low power applications or for TEC-less (Thermo-Electric-Cooler) applications, the flexible dilution architecture enables the system to operate the detector at a number of formats. This, together with a smooth frame rate and format transition capability turns SCD's uncooled detector to be well suited for unattended applications. These issues will be described in detail as well.
Vainer, Boris G
2005-12-07
This review gives an overview of focal plane array (FPA)-based infrared (IR) thermography as a powerful research method in the field of physiology and medicine. Comparison of the gained results with the data previously obtained by other authors with other research tools is given. Outer thermoregulatory manifestations displayed by the human organism subjected to whole-body heating (sauna bath) and physical loads (exercise bicycling) are quantitatively analysed. Some details of human body emotional sweating (psycho-physiological effect) are reported. Particular attention is paid to studying active sweat glands as individual objects. All experimental data were obtained with the help of a high-sensitivity (0.03 degrees C) fast 128 x 128 InAs IR detector-based thermal imaging system operating in the short-wave spectral region (2.5 to 3 microm) and perfectly suiting medical purposes. It is shown that IR thermography makes it possible to overcome limitations inherent to contact measuring means that were traditionally used before in thermal studies. It is also shown that heterogeneous thermograms displayed by organisms with disturbed inner equilibrium can be quantitatively analysed in terms of statistical parameters of related surface-temperature histograms, such as the mean temperature and the standard deviation of temperature (SDT). The increase and the decrease in SDT turned out to be typical of prolonged physical load and subsequent relaxation, and of external whole-body heating, respectively. Explanation of this result based on a hypothesis advanced within the context of the doctrine of human-organism evolution is given. Skin-temperature distribution function accompanying the relaxed organism in normality was found to closely resemble normal-distribution function. Symmetry break down and variation of the shape of this characteristic may serve as an indicator of homeostasis shift and can be used as a quantitative criterion for the latter. A new phenomenon, stable punctate hidrosis, is discovered and described. The term sweatology is introduced to refer to the discussed specific research area in biomedical science.
Low-cost thermo-electric infrared FPAs and their automotive applications
NASA Astrophysics Data System (ADS)
Hirota, Masaki; Ohta, Yoshimi; Fukuyama, Yasuhiro
2008-04-01
This paper describes three low-cost infrared focal plane arrays (FPAs) having a 1,536, 2,304, and 10,800 elements and experimental vehicle systems. They have a low-cost potential because each element consists of p-n polysilicon thermocouples, which allows the use of low-cost ultra-fine microfabrication technology commonly employed in the conventional semiconductor manufacturing processes. To increase the responsivity of FPA, we have developed a precisely patterned Au-black absorber that has high infrared absorptivity of more than 90%. The FPA having a 2,304 elements achieved high resposivity of 4,300 V/W. In order to reduce package cost, we developed a vacuum-sealed package integrated with a molded ZnS lens. The camera aiming the temperature measurement of a passenger cabin is compact and light weight devices that measures 45 x 45 x 30 mm and weighs 190 g. The camera achieves a noise equivalent temperature deviation (NETD) of less than 0.7°C from 0 to 40°C. In this paper, we also present a several experimental systems that use infrared cameras. One experimental system is a blind spot pedestrian warning system that employs four infrared cameras. It can detect the infrared radiation emitted from a human body and alerts the driver when a pedestrian is in a blind spot. The system can also prevent the vehicle from moving in the direction of the pedestrian. Another system uses a visible-light camera and infrared sensors to detect the presence of a pedestrian in a rear blind spot and alerts the driver. The third system is a new type of human-machine interface system that enables the driver to control the car's audio system without letting go of the steering wheel. Uncooled infrared cameras are still costly, which limits their automotive use to high-end luxury cars at present. To promote widespread use of IR imaging sensors on vehicles, we need to reduce their cost further.
Thermo-hydraulic actuator as a new way for conversion of solar energy in space
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sukhodolsky, A.T.
1998-07-01
A thermo-hydraulic actuator (THA) to directly convert the energy of continuous radiation into mechanical energy of vibration for use in power or propulsive systems in space is described. A THA consists of a chamber with an active liquid and optical fibers to deliver light energy inside. Power input comes from either argon laser or a solar concentrator 300 mm. in diameter. The principle of THA function is self-organization of a heat cycle that takes place by using a state of liquid (inversion) powered by light up to a temperature much higher than the temperature of boiling. As a result, anmore » excited state of liquid is able to form a single cavity to absorb thermal energy that is available to be converted by the non-equilibrium phase transition of first order into mechanical energy. This work stroke of a THA to form a hydraulic shock has been stimulated by non-linear mechanical motion of a single cavity and non-equilibrium phase transition of first order. The main feature of THA to accumulate energy of light in form of heat between sequential mechanical impulses gives the unique possibility to reach the motive forces induced by solar light by many order of the magnitude greater than the forces available by equilibrium radiation pressure. The first free-piston actuator (FPA) powered by solar light is also described. The construction consists of parabolic collector of diameter of 300mm and a transparent window with mounted actuator that has of a hollow piston with active liquid. Direct generation of hydraulic shocks by THA and preliminary experiments on generation of vibrations within a construction (FPA) has been proposed to be a new subject of interdisciplinary research to go from physical phenomenon observed in laser experiments to engineering development of new vibration machines powered by solar light. To conclude, a project to apply THA in new solar cosmic propulsive systems is discussed.« less
Barefoot plantar pressure measurement in Chronic Exertional Compartment Syndrome.
Roscoe, D; Roberts, A J; Hulse, D; Shaheen, A; Hughes, M P; Bennett, A
2018-04-09
Patients with Chronic Exertional Compartment Syndrome (CECS) have exercise-limiting pain that subsides at rest. Diagnosis is confirmed by intramuscular compartment pressure (IMCP) measurement. Accompanying CECS, subjective changes to gait (foot slap) are frequently reported by patients. This has not previously been investigated. The aim of this study was to investigate differences in barefoot plantar pressure (BFPP) between CECS cases and asymptomatic controls prior to the onset of painful symptoms. 40 male military volunteers, 20 with symptoms of CECS and 20 asymptomatic controls were studied. Alternative diagnoses were excluded with rigorous inclusion criteria, magnetic resonance imaging and dynamic IMCP measurement. BFPP was measured during walking and marching. Data were analysed for: Stance Time (ST); foot progression angle (FPA); centre of force; plantarflexion rate after heel strike (IFFC-time); the distribution of pressure under the heel; and, the ratio between inner and outer metatarsal loading. Correlation coefficients of each variable with speed and leg length were calculated followed by ANCOVA or t-test. Receiver operating characteristic (ROC) curves were constructed for IFFC-time. Caseshad shorter ST and IFFC-times than controls. FPA was inversely related to walking speed (WS) in controls only. The area under the ROC curve for IFFC-time ranged from 0.746 (95%CI: 0.636-0.87) to 0.773 (95%CI: 0.671-0.875) representing 'fair predictive validity'. Patients with CECS have an increased speed of ankle plantarflexion after heel strike that precedes the onset of painful symptoms likely resulting from a mechanical disadvantage of Tibialis Anterior. These findings provide further insight into the pathophysiology of CECS and support further investigation of this non-invasive diagnostic. The predictive value of IFFC-time in the diagnosis of CECS is comparable to post-exercise IMCP but falls short of dynamic IMCP measured during painful symptoms. Copyright © 2018. Published by Elsevier B.V.
NASA Technical Reports Server (NTRS)
Rutter, James; Libonate, Scott; Denley, Brian; Gurnee, Mark N.; Robillard, Gene
1996-01-01
The Atmospheric Infrared Sounder (AIRS) is a key facility instrument in the NASA Earth Observing System (EOS) program, being implemented to obtain comprehensive long-term measurements of earth processes affecting global change. The instrument performs passive IR remote sensing using a high resolution grating spectrometer with a wide spectral coverage (3.7 - 15.4 m) directing radiation onto a hybrid HgCdTe IRFPA operating at 58K in a vacuum package cooled to 155K. The hybrid HgCdTe FPA consists of twelve modules, 10 with multiplexed photovoltaic detectors and two with individually leaded out photoconductive detectors. The complex FPA has a large optical footprint, 53 mm x 66 mm, and receives energy dispersed from the grating through a precision filter assembly containing 17 narrow band filters. The backside illuminated PV detector arrays are fabricated from P-on-n double layer LPE grown heterojunction detectors in a bilinear format of 50 m x 100 m detectors, with from 232 to 420 detectors per module. For the MWIR bands four PV modules cover the 3.7 m to 8.22 m region. Low detector capacitance and low noise preamplifiers in the ROIC are key to achieving high sensitivities in these bands. Uniform quantum efficiencies and detectivities exceeding 3E13 cm-rtHz/W have been achieved. The LWIR region is covered by six PV modules spanning 8.8 m to 13.75 m. High detector resistance and very low ROIC preamplifier input noise are key to achieving high sensitivity. A detectivity exceeding 2E11 cm-rtHz/W has been achieved at the longest wavelength. Two additional PC modules cover the longest spectral bands out to 15.4 m. This high performance multispectral focal plane has been built and integrated with the dewar assembly, and is currently being integrated with the complete AIRS sensor.
P Wrobel, Tomasz; Mateuszuk, Lukasz; Chlopicki, Stefan; Malek, Kamilla; Baranska, Malgorzata
2011-12-21
Spectroscopy-based approaches can provide an insight into the biochemical composition of a tissue sample. In the present work Fourier transform infrared (FT-IR) spectroscopy was used to develop a reliable methodology to study the content of free fatty acids, triglycerides, cholesteryl esters as well as cholesterol in aorta from mice with atherosclerosis (ApoE/LDLR(-/-) mice). In particular, distribution and concentration of palmitic, oleic and linoleic acid derivatives were analyzed. Spectral analysis of pure compounds allowed for clear discrimination between free fatty acids and other similar moieties based on the carbonyl band position (1699-1710 cm(-1) range). In order to distinguish cholesteryl esters from triglycerides a ratio of carbonyl band to signal at 1010 cm(-1) was used. Imaging of lipids in atherosclerotic aortic lesions in ApoE/LDLR(-/-) mice was followed by Hierarchical Cluster Analysis (HCA). The aorta from C57Bl/6J control mice (fed with chow diet) was used for comparison. The measurements were completed with an FT-IR spectrometer equipped with a 128 × 128 FPA detector. In cross-section of aorta from ApoE/LDLR(-/-) mice a region of atherosclerotic plaque was clearly identified by HCA, which was later divided into 2 sub-regions, one characterized by the higher content of cholesterol, while the other by higher contents of cholesteryl esters. HCA of tissues deposited on normal microscopic glass, hence limited to the 2200-3800 cm(-1) spectral range, also identified a region of atherosclerotic plaque. Importantly, this region correlates with the area stained by standard histological staining for atherosclerotic plaque (Oil Red O). In conclusion, the use of FT-IR and HCA may provide a novel tool for qualitative and quantitative analysis of contents and distribution of lipids in atherosclerotic plaque.
Pilling, Michael J; Henderson, Alex; Bird, Benjamin; Brown, Mick D; Clarke, Noel W; Gardner, Peter
2016-06-23
Infrared microscopy has become one of the key techniques in the biomedical research field for interrogating tissue. In partnership with multivariate analysis and machine learning techniques, it has become widely accepted as a method that can distinguish between normal and cancerous tissue with both high sensitivity and high specificity. While spectral histopathology (SHP) is highly promising for improved clinical diagnosis, several practical barriers currently exist, which need to be addressed before successful implementation in the clinic. Sample throughput and speed of acquisition are key barriers and have been driven by the high volume of samples awaiting histopathological examination. FTIR chemical imaging utilising FPA technology is currently state-of-the-art for infrared chemical imaging, and recent advances in its technology have dramatically reduced acquisition times. Despite this, infrared microscopy measurements on a tissue microarray (TMA), often encompassing several million spectra, takes several hours to acquire. The problem lies with the vast quantities of data that FTIR collects; each pixel in a chemical image is derived from a full infrared spectrum, itself composed of thousands of individual data points. Furthermore, data management is quickly becoming a barrier to clinical translation and poses the question of how to store these incessantly growing data sets. Recently, doubts have been raised as to whether the full spectral range is actually required for accurate disease diagnosis using SHP. These studies suggest that once spectral biomarkers have been predetermined it may be possible to diagnose disease based on a limited number of discrete spectral features. In this current study, we explore the possibility of utilising discrete frequency chemical imaging for acquiring high-throughput, high-resolution chemical images. Utilising a quantum cascade laser imaging microscope with discrete frequency collection at key diagnostic wavelengths, we demonstrate that we can diagnose prostate cancer with high sensitivity and specificity. Finally we extend the study to a large patient dataset utilising tissue microarrays, and show that high sensitivity and specificity can be achieved using high-throughput, rapid data collection, thereby paving the way for practical implementation in the clinic.
1993-03-01
8 2.3 De Flyer Plate Assembly (.FPA) 9 3 OPZET VAN DE MFTThIGEN 11 3.1 De djfferentjaalstroommetiflg 11 3.2 Stroommetingen 12 3.3...25 n11)" II )60 S. L) I.P014 25 ,rzit II ,0 8 9 28 ).7 I 10.7 273.0 2.15 43790 1.318 - - - IM,I5 25 Nr. 11 60 8.9 279.t) 125.9 274.1 2.22 44406 1...4 HWO-KLU 5 HWO-KM 6 DMKL J.A. van Gool 7/ 9 TDCK 10 Hoofddirecteur DO-TNO 11 Lid Inst jtuuts Advies Raad PMIL Prof. drs. P.J. van den Berg 12 Lid
Optomechanical System Development of the AWARE Gigapixel Scale Camera
NASA Astrophysics Data System (ADS)
Son, Hui S.
Electronic focal plane arrays (FPA) such as CMOS and CCD sensors have dramatically improved to the point that digital cameras have essentially phased out film (except in very niche applications such as hobby photography and cinema). However, the traditional method of mating a single lens assembly to a single detector plane, as required for film cameras, is still the dominant design used in cameras today. The use of electronic sensors and their ability to capture digital signals that can be processed and manipulated post acquisition offers much more freedom of design at system levels and opens up many interesting possibilities for the next generation of computational imaging systems. The AWARE gigapixel scale camera is one such computational imaging system. By utilizing a multiscale optical design, in which a large aperture objective lens is mated with an array of smaller, well corrected relay lenses, we are able to build an optically simple system that is capable of capturing gigapixel scale images via post acquisition stitching of the individual pictures from the array. Properly shaping the array of digital cameras allows us to form an effectively continuous focal surface using off the shelf (OTS) flat sensor technology. This dissertation details developments and physical implementations of the AWARE system architecture. It illustrates the optomechanical design principles and system integration strategies we have developed through the course of the project by summarizing the results of the two design phases for AWARE: AWARE-2 and AWARE-10. These systems represent significant advancements in the pursuit of scalable, commercially viable snapshot gigapixel imaging systems and should serve as a foundation for future development of such systems.
Performance evaluation of infrared imaging system in field test
NASA Astrophysics Data System (ADS)
Wang, Chensheng; Guo, Xiaodong; Ren, Tingting; Zhang, Zhi-jie
2014-11-01
Infrared imaging system has been applied widely in both military and civilian fields. Since the infrared imager has various types and different parameters, for system manufacturers and customers, there is great demand for evaluating the performance of IR imaging systems with a standard tool or platform. Since the first generation IR imager was developed, the standard method to assess the performance has been the MRTD or related improved methods which are not perfect adaptable for current linear scanning imager or 2D staring imager based on FPA detector. For this problem, this paper describes an evaluation method based on the triangular orientation discrimination metric which is considered as the effective and emerging method to evaluate the synthesis performance of EO system. To realize the evaluation in field test, an experiment instrument is developed. And considering the importance of operational environment, the field test is carried in practical atmospheric environment. The test imagers include panoramic imaging system and staring imaging systems with different optics and detectors parameters (both cooled and uncooled). After showing the instrument and experiment setup, the experiment results are shown. The target range performance is analyzed and discussed. In data analysis part, the article gives the range prediction values obtained from TOD method, MRTD method and practical experiment, and shows the analysis and results discussion. The experimental results prove the effectiveness of this evaluation tool, and it can be taken as a platform to give the uniform performance prediction reference.
Factors affecting the water odor caused by chloramines during drinking water disinfection.
Wang, An-Qi; Lin, Yi-Li; Xu, Bin; Hu, Chen-Yan; Gao, Ze-Chen; Liu, Zhi; Cao, Tong-Cheng; Gao, Nai-Yun
2018-10-15
Chloramine disinfection is one of the most common disinfection methods in drinking water treatment. In this study, the temporal variability of water odors during monochloramine auto-decomposition was investigated to elucidate the characteristics of odor problems caused by adopting chloramine disinfection in tap water. Odor intensities and dominant odorant contributions were determined using the flavor profile analysis (FPA) and odor active value (OAV), respectively. During auto-decomposition of monochloramine, Cl 2 /N molar ratio, pH, temperature, and the presence of NOM all affected odor intensity and odor temporal variation in drinking water. In general, decreasing pH from 8.5 to 6.0 led to increasing perceived odor intensity due to the formation of dichloramine. The major odorants responsible for chlorinous odor under acidic and non-acidic conditions were dichloramine and monochloramine, respectively. Chloraminated water with a Cl 2 /N molar ratio of 0.6 or NOM concentration <2 mg-C L -1 inhibited odor intensity. Furthermore, the influence of rechlorination on chlorinous odor intensity for chloraminated water should not be neglected. The results of this study will be beneficial for the control of chlorinous odors caused by chloramine disinfection in drinking water. Copyright © 2018 Elsevier B.V. All rights reserved.
Dehydration stress extends mRNA 3′ untranslated regions with noncoding RNA functions in Arabidopsis
Sun, Hai-Xi; Li, Yan; Niu, Qi-Wen; Chua, Nam-Hai
2017-01-01
The 3′ untranslated regions (3′ UTRs) of mRNAs play important roles in the regulation of mRNA localization, translation, and stability. Alternative cleavage and polyadenylation (APA) generates mRNAs with different 3′ UTRs, but the involvement of this process in stress response has not yet been clarified. Here, we report that a subset of stress-related genes exhibits 3′ UTR extensions of their mRNAs during dehydration stress. These extended 3′ UTRs have characteristics of long noncoding RNAs and likely do not interact with miRNAs. Functional studies using T-DNA insertion mutants reveal that they can act as antisense transcripts to repress expression levels of sense genes from the opposite strand or can activate the transcription or lead to read-through transcription of their downstream genes. Further analysis suggests that transcripts with 3′ UTR extensions have weaker poly(A) signals than those without 3′ UTR extensions. Finally, we show that their biogenesis is partially dependent on a trans-acting factor FPA. Taken together, we report that dehydration stress could induce transcript 3′ UTR extensions and elucidate a novel function for these stress-induced 3′ UTR extensions as long noncoding RNAs in the regulation of their neighboring genes. PMID:28522613
Design of a long focal length mid-wavelength infrared optical system
NASA Astrophysics Data System (ADS)
Duan, Jing; Zhang, Zhanpeng; Liu, Kai; Shan, Qiusha; Jiang, Kai; Yan, Peipei
2018-02-01
Based on a 640×512 cooled staring focal plane array (FPA) detector, pixel size 15μm×15μm, a long focal length mid-wavelength infrared optical system was designed. In this paper, the working wavelength is 3μm 5μm, the temperature range is -30°C +50°C, this system can realize 1000mm focal length, the F-number is 4, the full field of view is 0.70°, satisfy 100% cold shield efficiency. A re-imaging refractive system was adopted in this designed optical system consists of a main objective group and a projection group. First of all, the structural selection and the initial parameter calculation were introduced. Secondly, on the basis of variety of the temperature, a focusing len was presented in this system to adjust to produce a clear image. Last but not the least, to improve image quality and environment adaptability, the analysis of temperature change and ghost image were described particularly. The design results prove that at the spatial frequency of 33 lp/mm, the axis MTF of the optical system is greater than 0.35, the system can offer a high resolution and excellent images, and it has the advantages of good adaptability, simple structure, easy to adjust, and high transmittance.
150-nm generation lithography equipment
NASA Astrophysics Data System (ADS)
Deguchi, Nobuyoshi; Uzawa, Shigeyuki
1999-07-01
Lithography by step-and-scan exposure is expected to be the mainstream for semiconductor manufacturing below 180 nm resolution patterns. We have developed a scanner for 150 nm features on either 200 mm or 300 mm wafers. For this system, the synchronous stage system has been redesigned which makes it possible to improve imaging performance and overlay accuracy. A new 300 mm wafer stage enhances productivity while weighting almost the same as the stage for 200 mm wafers. The mainbody mechanical frame incorporates reactive force receiver system to counter the inertial energy and vibrational issues associated with high speed wafer and reticle stage scanning. This report outlines the total system design, new technologies and performance data of the Cannon FPA-5000ES2 step-and-scan exposure tool developed for the 150 nm generation lithography.
NASA Technical Reports Server (NTRS)
Gunapala, Sarath D.; Bandara, Sumith V.; Hill, Cory J.; Ting, David Z.; Liu, John K.; Rafol, Sir B.; Blazejewski, Edward R.; Mumolo, Jason M.; Keo, Sam A.; Krishna, Sanjay;
2007-01-01
Epitaxially grown self-assembled. InAs-InGaAs-GaAs quantum dots (QDs) are exploited for the development of large-format long-wavelength infrared focal plane arrays (FPAs). The dot-in-a-well (DWELL) structures were experimentally shown to absorb both 45 degrees and normal incident light, therefore, a reflection grating structure was used to enhance the quantum efficiency. The devices exhibit peak responsivity out to 8.1 micrometers, with peak detectivity reaching approximately 1 X 10(exp 10) Jones at 77 K. The devices were fabricated into the first long-wavelength 640 x 512 pixel QD infrared photodetector imaging FPA, which has produced excellent infrared imagery with noise equivalent temperature difference of 40 mK at 60-K operating temperature.
Probiotics Can Induce Follicle Maturational Competence: The Danio rerio Case1
Gioacchini, Giorgia; Giorgini, Elisabetta; Merrifield, Daniel L.; Hardiman, Gary; Borini, Andrea; Vaccari, Lisa; Carnevali, Oliana
2011-01-01
ABSTRACT In the present study, the effects of the probiotic Lactobacillus rhamnosus IMC 501 on the acquisition of oocyte maturational competence was examined in zebrafish (Danio rerio). L. rhamnosus administration induced the responsiveness of incompetent follicles (stage IIIa) to 17,20-dihydroxy-4-pregnen-3-one and their in vitro maturation. Acquisition of competence by the stage IIIa follicles was further validated by changes of lhr, mprb, inhbaa (activin betaA1), tgfb1, and gdf9 gene expression, which have recently emerged as key regulators of oocyte acquisition of maturational competence, and pou5f1 gene expression, which in other models has been shown to govern the establishment of developmental competence of oocytes. In addition, a DNA microarray experiment was conducted using the same follicles, and with relative gene ontology (GO) data analysis, the molecular effects of probiotic administration emerged. Molecular analysis using PCR-DGGE (denaturing gradient gel electrophoresis) approach, providing information about only the most abundant bacterial members of the microbial community, revealed that the probiotic was able to populate the gastrointestinal tract and modulate the microbial communities, causing a clear shift in them and specifically enhancing the presence of the lactic acid bacteria Streptococcus thermophilus. At the same time, PCR-DGGE analysis revealed that the probiotic was not directly associated with the ovaries. Finally, the effects of probiotic treatment on zebrafish follicle development were also analyzed by FPA (focal plane array) Fourier transform-infrared (FT-IR) imaging, a technique that provides the overall biochemical composition of samples. Changes were found above all in stage IIIa follicles from probiotic-exposed females; the modifications, observed in protein secondary structures as well as in hydration and in bands related to phosphate moieties, allowed us to hypothesize that probiotics act at this follicle stage, affecting the maturation phase. PMID:22088919
RNA mediated assembly of nanostructures
NASA Astrophysics Data System (ADS)
Rouge, Jessica Lynn
The first chapter of this work presents a comprehensive look at RNA mediated nanoparticle formation. The overall goal of this research is to gain a deeper understanding of the RNA-particle formation mechanism and the basic properties of the materials selected by modified RNA molecules. Understanding such RNA-substrate interactions and how they translate into the physical and chemical characteristics of the nanoparticles they create are important fundamental concepts when considering these biotemplated materials as potential chemical catalysts. The RNA sequences discussed in the first chapter (referred to as Pdases) were discovered using RNA in vitro selection techniques. These Pdases were found to be capable of forming inorganic palladium (Pd) containing nanoparticles with impressive control over an individual particle's size and shape, despite incubation with the same organometallic precursor. This discovery held exciting implications for inorganic nanoparticle design while also generating numerous questions regarding the mechanism of RNA mediated particle growth. The central question that arose after this initial discovery was how could a biomolecule be used to tailor the physical size and shape of inorganic materials? Starting with a chemical proof designed to uncover the composition of the nanoparticles formed by RNA mediation, this chapter investigates the basic material properties of the nanoparticles while also introducing surprising results regarding the effect of multiple sequences on nanoparticle growth outcomes. In the second chapter, the experiments shift to developing methods to investigate nanoparticle growth mechanisms by fluorescence spectroscopy. A fluorescence polarization anisotropy (FPA) assay is presented in which the strengths of the technique are adapted for studying the formation of RNA mediated Pd nanoparticles in real time. This is a unique application of FPA, as it has been adapted to encompass both the biochemical and materials analysis of a single dynamic system. Although the initial studies described in chapter two focus on the growth kinetics of selected Pdases and their organometallic substrate (Pd2DBA3), it is envisioned that this technique can be used to study a variety of biotemplated systems in a similar fashion. For the experiments described, a key interest was to understand if the RNA governed the rates associated with nanoparticle formation and to gain deeper insight in to the potential growth mechanisms of RNA-nanoparticle constructs. Understanding such interactions could help identify the role RNA play in forming materials while also helping to shape the experimental design of future in vitro selections between RNA and materials. The strengths of these FPA experiments are described as well the associated kinetics observed for RNA mediated particle growth. In chapter three, the fundamental concepts surrounding RNA-nanoparticle interactions shifts to the first application-oriented study of RNA mediated nanoparticle formation for chemical catalysis. The product of a second materials selection is presented in which platinum (Pt) rich nanoparticles are formed using pyridyl modified RNA sequences. These RNA-Pt nanoparticle constructs are interfaced with cadmium sulfide (CdS) quantum dots in an effort to assess the ability of the RNA-Pt nanoparticles to serve as functional catalyst for the photocatalytic production of metal hydrides from aqueous solutions at neutral pH. Metal hydride formation is a crucial step in the challenging chemical reaction of water splitting. The results of this hybrid RNA-Pt/CdS water splitting catalyst are described and compared to more traditional catalyst designs. In the final chapter, the combination of concepts and insights gained as presented in chapters 1-3 are systematically combined into the first RNA in vitro selection for photochemically active materials. This novel selection utilizes an RNA library that is chemically modified such that it can both find and assess the ability of a material to perform photon-driven oxidation chemistry in a complex mixture. In order to conduct such a selection, a new DNA phosphoramidite was synthesized and attached to the RNA library prior to beginning the selection. The details of this synthesis are described. Later in this chapter, the results of this complex yet powerful in vitro selection are outlined. In closing, the prospect of using in vitro selection techniques for discovering other chemically active materials is discussed.
IR sensors and imagers in networked operations
NASA Astrophysics Data System (ADS)
Breiter, Rainer; Cabanski, Wolfgang
2005-05-01
"Network-centric Warfare" is a common slogan describing an overall concept of networked operation of sensors, information and weapons to gain command and control superiority. Referring to IR sensors, integration and fusion of different channels like day/night or SAR images or the ability to spread image data among various users are typical requirements. Looking for concrete implementations the German Army future infantryman IdZ is an example where a group of ten soldiers build a unit with every soldier equipped with a personal digital assistant (PDA) for information display, day photo camera and a high performance thermal imager for every unit. The challenge to allow networked operation among such a unit is bringing information together and distribution over a capable network. So also AIM's thermal reconnaissance and targeting sight HuntIR which was selected for the IdZ program provides this capabilities by an optional wireless interface. Besides the global approach of Network-centric Warfare network technology can also be an interesting solution for digital image data distribution and signal processing behind the FPA replacing analog video networks or specific point to point interfaces. The resulting architecture can provide capabilities of data fusion from e.g. IR dual-band or IR multicolor sensors. AIM has participated in a German/UK collaboration program to produce a demonstrator for day/IR video distribution via Gigabit Ethernet for vehicle applications. In this study Ethernet technology was chosen for network implementation and a set of electronics was developed for capturing video data of IR and day imagers and Gigabit Ethernet video distribution. The demonstrator setup follows the requirements of current and future vehicles having a set of day and night imager cameras and a crew station with several members. Replacing the analog video path by a digital video network also makes it easy to implement embedded training by simply feeding the network with simulation data. The paper addresses the special capabilities, requirements and design considerations of IR sensors and imagers in applications like thermal weapon sights and UAVs for networked operating infantry forces.
High-performance IR detectors at SCD present and future
NASA Astrophysics Data System (ADS)
Nesher, O.; Klipstein, P. C.
2005-09-01
For over 27 years, SCD has been manufacturing and developing a wide range of high performance infra-red detectors, designed to operate in either the mid-wave (MWIR) or the long-wave (LWIR) atmospheric windows. These detectors have been integrated successfully into many different types of system including missile seekers, Time Delay Integration scanning systems, Hand-Held cameras, Missile Warning Systems and many others. SCD's technology for the MWIR wavelength range is based on its well established 2-D arrays of InSb photodiodes. The arrays are flip-chip bonded to SCD's analogue or digital signal processors, all of which have been designed in-house. The 2-D Focal Plane Array (FPA) detectors have a format of 320×256 elements for a 30 μm pitch and 480×384 or 640×512 elements for a 20 μm pitch. Typical operating temperatures are around 77-85K. Five years ago SCD began to develop a new generation of MWIR detectors based on the epitaxial growth of Antimonide Based Compound Semiconductors (ABCS). This ABCS technology allows band-gap engineering of the detection material which enables higher operating temperatures and multi-spectral detection. This year SCD presented its first prototype FPA from this program, an InAlSb based detector operating at a temperature of 100 K. By the end of this year SCD will introduce the first prototype MWIR detector with a 640×512 element format and a pitch of 15 μm. For the LWIR wave-length range SCD manufactures both linear Hg1-xCdxTe (MCT) detectors with a line of 250 elements and Time Delay and Integration (TDI) detectors with formats of 288×4 and 480×6. Recently, SCD has demonstrated its first prototype un-cooled detector which is based on VOx technology and which has a format of 384×288 elements, a pitch of 25 μm and a typical NETD of 50mK at F/1. In this paper we describe the present technologies and products of SCD and the future evolution of our detectors for the MWIR and LWIR detection.