Mentoring for population health in general practice divisions.
Moss, John R; Mickan, Sharon M; Fuller, Jeffrey D; Procter, Nicholas G; Waters, Barb A; O'Rourke, Peter K
2006-02-01
This paper describes the implementation and evaluation of a three-way model of service development mentoring. This population health mentoring program was funded by the Commonwealth Department of Health and Ageing to enable staff from eight Divisions of General Practice in South Australia to gain a sound understanding of population health concepts relevant to their workplace. The distinguishing features of service development mentoring were that the learning was grounded within an individual's work setting and experience; there was an identified population health problem or issue confronting the Division of General Practice; and there was an expectation of enhanced organisational performance. A formal evaluation found a consensus among all learners that mentoring was a positive and worthwhile experience, where they had achieved what they had set out to do. Mentors found the model of learning agreeable and effective. Division executive officers recognised enhanced skills among their "learner" colleagues, and commented positively on the benefits to their organisations through the development of well researched and relevant projects, with the potential to improve the efficiency of their population health activities.
Counselors as Consultants during a National Crisis.
ERIC Educational Resources Information Center
Kaplan, Leslie S.; And Others
1993-01-01
Describes how counselors served as consultants to school division that had large student population of military dependents during Persian Gulf War. Examines impact of Persian Gulf War on the school division and its students and presents model for counselors who serve as consultants during crisis. Discusses counselors working as team with teachers,…
15 CFR 90.9 - Review of challenge.
Code of Federal Regulations, 2014 CFR
2014-01-01
..., DEPARTMENT OF COMMERCE PROCEDURE FOR CHALLENGING POPULATION ESTIMATES § 90.9 Review of challenge. The Chief, Population Division, Census Bureau, or the Chief's designee shall review the evidence provided with the request for the population estimate challenge, shall work with the governmental unit to verify the data...
Stochastic Individual-Based Modeling of Bacterial Growth and Division Using Flow Cytometry.
García, Míriam R; Vázquez, José A; Teixeira, Isabel G; Alonso, Antonio A
2017-01-01
A realistic description of the variability in bacterial growth and division is critical to produce reliable predictions of safety risks along the food chain. Individual-based modeling of bacteria provides the theoretical framework to deal with this variability, but it requires information about the individual behavior of bacteria inside populations. In this work, we overcome this problem by estimating the individual behavior of bacteria from population statistics obtained with flow cytometry. For this objective, a stochastic individual-based modeling framework is defined based on standard assumptions during division and exponential growth. The unknown single-cell parameters required for running the individual-based modeling simulations, such as cell size growth rate, are estimated from the flow cytometry data. Instead of using directly the individual-based model, we make use of a modified Fokker-Plank equation. This only equation simulates the population statistics in function of the unknown single-cell parameters. We test the validity of the approach by modeling the growth and division of Pediococcus acidilactici within the exponential phase. Estimations reveal the statistics of cell growth and division using only data from flow cytometry at a given time. From the relationship between the mother and daughter volumes, we also predict that P. acidilactici divide into two successive parallel planes.
Work Experience of the Population in 1972.
ERIC Educational Resources Information Center
Young, Anne M.
Based on the March 1973 survey for the Bureau of Labor Statistics by the Division of Labor Force Studies, the report shows that the proportion of workers employed full-time all year (1972) increased, mainly because of expansion in the service-producing industries. The survey provides information on the number of persons who worked at some time,…
Surgery on Fetus Reduces Complications of Spina Bifida
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ERIC Educational Resources Information Center
United Nations Economic and Social Commission for Asia and the Pacific, Bangkok (Thailand).
This monograph contains a study conducted by the Population Division of the United Nations Economic and Social Committee for Asia and the Pacific (ESCAP). The document is designed to aid policy-makers, administrators and evaluation personnel in family planning programs in the ESCAP region, primarily; and researchers working in the field of family…
Population patterns in World’s administrative units
Miramontes, Pedro; Cocho, Germinal
2017-01-01
Whereas there has been an extended discussion concerning city population distribution, little has been said about that of administrative divisions. In this work, we investigate the population distribution of second-level administrative units of 150 countries and territories and propose the discrete generalized beta distribution (DGBD) rank-size function to describe the data. After testing the balance between the goodness of fit and number of parameters of this function compared with a power law, which is the most common model for city population, the DGBD is a good statistical model for 96% of our datasets and preferred over a power law in almost every case. Moreover, the DGBD is preferred over a power law for fitting country population data, which can be seen as the zeroth-level administrative unit. We present a computational toy model to simulate the formation of administrative divisions in one dimension and give numerical evidence that the DGBD arises from a particular case of this model. This model, along with the fitting of the DGBD, proves adequate in reproducing and describing local unit evolution and its effect on the population distribution. PMID:28791153
[Role of "Health" National project in improvement of health parameters in working population].
Bykovskaia, T Iu
2011-01-01
The author analyzed results of "Health" National project accomplishment in Rostov region over 2006-2009. Findings are that quality of primary medical care has improved, material and technical basis of municipal health care institutions has progressed, salary of primary health care division specialists has increased. Over this period, infant mortality and mortality among able-bodied population in the region has decreased, birth rate has increased, coefficient of natural loss of population has reduced, life expectancy has increased.
Noise and Epigenetic Inheritance of Single-Cell Division Times Influence Population Fitness.
Cerulus, Bram; New, Aaron M; Pougach, Ksenia; Verstrepen, Kevin J
2016-05-09
The fitness effect of biological noise remains unclear. For example, even within clonal microbial populations, individual cells grow at different speeds. Although it is known that the individuals' mean growth speed can affect population-level fitness, it is unclear how or whether growth speed heterogeneity itself is subject to natural selection. Here, we show that noisy single-cell division times can significantly affect population-level growth rate. Using time-lapse microscopy to measure the division times of thousands of individual S. cerevisiae cells across different genetic and environmental backgrounds, we find that the length of individual cells' division times can vary substantially between clonal individuals and that sublineages often show epigenetic inheritance of division times. By combining these experimental measurements with mathematical modeling, we find that, for a given mean division time, increasing heterogeneity and epigenetic inheritance of division times increases the population growth rate. Furthermore, we demonstrate that the heterogeneity and epigenetic inheritance of single-cell division times can be linked with variation in the expression of catabolic genes. Taken together, our results reveal how a change in noisy single-cell behaviors can directly influence fitness through dynamics that operate independently of effects caused by changes to the mean. These results not only allow a better understanding of microbial fitness but also help to more accurately predict fitness in other clonal populations, such as tumors. Copyright © 2016 Elsevier Ltd. All rights reserved.
Stationary Size Distributions of Growing Cells with Binary and Multiple Cell Division
NASA Astrophysics Data System (ADS)
Rading, M. M.; Engel, T. A.; Lipowsky, R.; Valleriani, A.
2011-10-01
Populations of unicellular organisms that grow under constant environmental conditions are considered theoretically. The size distribution of these cells is calculated analytically, both for the usual process of binary division, in which one mother cell produces always two daughter cells, and for the more complex process of multiple division, in which one mother cell can produce 2 n daughter cells with n=1,2,3,… . The latter mode of division is inspired by the unicellular algae Chlamydomonas reinhardtii. The uniform response of the whole population to different environmental conditions is encoded in the individual rates of growth and division of the cells. The analytical treatment of the problem is based on size-dependent rules for cell growth and stochastic transition processes for cell division. The comparison between binary and multiple division shows that these different division processes lead to qualitatively different results for the size distribution and the population growth rates.
Health in police officers: Role of risk factor clusters and police divisions.
Habersaat, Stephanie A; Geiger, Ashley M; Abdellaoui, Sid; Wolf, Jutta M
2015-10-01
Law enforcement is a stressful occupation associated with significant health problems. To date, most studies have focused on one specific factor or one domain of risk factors (e.g., organizational, personal). However, it is more likely that specific combinations of risk factors are differentially health relevant and further, depend on the area of police work. A self-selected group of officers from the criminal, community, and emergency division (N = 84) of a Swiss state police department answered questionnaires assessing personal and organizational risk factors as well as mental and physical health indicators. In general, few differences were observed across divisions in terms of risk factors or health indicators. Cluster analysis of all risk factors established a high-risk and a low-risk cluster with significant links to all mental health outcomes. Risk cluster-by-division interactions revealed that, in the high-risk cluster, Emergency officers reported fewer physical symptoms, while community officers reported more posttraumatic stress symptoms. Criminal officers in the high-risk cluster tended to perceived more stress. Finally, perceived stress did not mediate the relationship between risk clusters and posttraumatic stress symptoms. In summary, our results support the notion that police officers are a heterogeneous population in terms of processes linking risk factors and health indicators. This heterogeneity thereby appeared to be more dependent on personal factors and individuals' perception of their own work conditions than division-specific work environments. Our findings further suggest that stress-reduction interventions that do not target job-relevant sources of stress may only show limited effectiveness in reducing health risks associated with police work. Copyright © 2015 Elsevier Ltd. All rights reserved.
Health in police officers: Role of risk factor clusters and police divisions
Habersaat, Stephanie A.; Geiger, Ashley M.; Abdellaoui, Sid; Wolf, Jutta M.
2015-01-01
Objective Law enforcement is a stressful occupation associated with significant health problems. To date, most studies have focused on one specific factor or one domain of risk factors (e.g., organizational, personal). However, it is more likely that specific combinations of risk factors are differentially health relevant and further, depend on the area of police work. Methods A self-selected group of officers from the criminal, community, and emergency division (N = 84) of a Swiss state police department answered questionnaires assessing personal and organizational risk factors as well as mental and physical health indicators. Results In general, few differences were observed across divisions in terms of risk factors or health indicators. Cluster analysis of all risk factors established a high-risk and a low-risk cluster with significant links to all mental health outcomes. Risk cluster-by-division interactions revealed that, in the high-risk cluster, Emergency officers reported fewer physical symptoms, while community officers reported more posttraumatic stress symptoms. Criminal officers in the high-risk cluster tended to perceived more stress. Finally, perceived stress did not mediate the relationship between risk clusters and posttraumatic stress symptoms. Conclusion In summary, our results support the notion that police officers are a heterogeneous population in terms of processes linking risk factors and health indicators. This heterogeneity thereby appeared to be more dependent on personal factors and individuals' perception of their own work conditions than division-specific work environments. Our findings further suggest that stress-reduction interventions that do not target job-relevant sources of stress may only show limited effectiveness in reducing health risks associated with police work. PMID:26364008
Measuring rural women's work and class position.
Deere, C D; León de Leal, M
1979-01-01
On the basis of experience gained in researching the economic roles of rural women in a national level study in Colombia and in a regional level study in Peru, some of the methodological problems of measuring rural women's economic participation by sample survey are considered. The specific objective of the sample surveys was to quantify the existing sexual division of labor among the peasant population. The rural household was the unit of analysis, and the focus of measurement was the division of labor by sex in such activities as daily maintenance, household production, and income-generating activitives pursued outside the household. The focus of the survey questionnaire is on the sexual division of labor, but it necessarily must be related to another series of socioeconomic or cultural variables for analysis. The selection of these variables needs to be derived from the hypotheses guiding the study, yet much attention must be given to narrowing the range of inquiry. The time constraint on the length of the questionnaire requires that certain choices be made in terms of the complementary variables to be included. The most important problem in the design of a representative sample survey is the selection of the population to be sampled. The choice of population needs to be compatible with the theoretical framework. Since the interest was to measure the sexual division of labor in terms of class formation, the sample had to be representative of the different class strata in the rural areas. The measurement of access to means of production ideally should be quantitative and qualitative. The choice of the population to be sampled is also constrained by the available data base, a particular problem in rural areas.
Wagman, Petra; Nordin, Maria; Alfredsson, Lars; Westerholm, Peter J M; Fransson, Eleonor I
2017-01-01
The amount and perception of domestic work may affect satisfaction with everyday life, but further knowledge is needed about the relationship between domestic work division and health and well-being. To describe the division of, and satisfaction with, domestic work and responsibility for home/family in adults living with a partner. A further aim was to investigate the associations between these aspects and self-rated life satisfaction and health. Data from the Work, Lipids and Fibrinogen survey collected 2009 were used, comprising 4924 participants living with a partner. Data were analyzed using logistic regression. The majority shared domestic work and responsibility for home/family equally with their partner. However, more women conducted the majority of the domestic work and were less satisfied with its division. When both division and satisfaction with division was included in the analysis, solely satisfaction with the division and the responsibility were associated with higher odds for good life satisfaction. Regarding health, higher odds for good self-rated health were seen in those who were satisfied with their division of responsibility. The results highlight the importance of taking into account not solely the actual division of domestic work but also the satisfaction with it.
Bridging the Timescales of Single-Cell and Population Dynamics
NASA Astrophysics Data System (ADS)
Jafarpour, Farshid; Wright, Charles S.; Gudjonson, Herman; Riebling, Jedidiah; Dawson, Emma; Lo, Klevin; Fiebig, Aretha; Crosson, Sean; Dinner, Aaron R.; Iyer-Biswas, Srividya
2018-04-01
How are granular details of stochastic growth and division of individual cells reflected in smooth deterministic growth of population numbers? We provide an integrated, multiscale perspective of microbial growth dynamics by formulating a data-validated theoretical framework that accounts for observables at both single-cell and population scales. We derive exact analytical complete time-dependent solutions to cell-age distributions and population growth rates as functionals of the underlying interdivision time distributions, for symmetric and asymmetric cell division. These results provide insights into the surprising implications of stochastic single-cell dynamics for population growth. Using our results for asymmetric division, we deduce the time to transition from the reproductively quiescent (swarmer) to the replication-competent (stalked) stage of the Caulobacter crescentus life cycle. Remarkably, population numbers can spontaneously oscillate with time. We elucidate the physics leading to these population oscillations. For C. crescentus cells, we show that a simple measurement of the population growth rate, for a given growth condition, is sufficient to characterize the condition-specific cellular unit of time and, thus, yields the mean (single-cell) growth and division timescales, fluctuations in cell division times, the cell-age distribution, and the quiescence timescale.
Quantitative regulation of B cell division destiny by signal strength.
Turner, Marian L; Hawkins, Edwin D; Hodgkin, Philip D
2008-07-01
Differentiation to Ab secreting and isotype-switched effector cells is tightly linked to cell division and therefore the degree of proliferation strongly influences the nature of the immune response. The maximum number of divisions reached, termed the population division destiny, is stochastically distributed in the population and is an important parameter in the quantitative outcome of lymphocyte responses. In this study, we further assessed the variables that regulate B cell division destiny in vitro in response to T cell- and TLR-dependent stimuli. Both the concentration and duration of stimulation were able to regulate the average maximum number of divisions undergone for each stimulus. Notably, a maximum division destiny was reached during provision of repeated saturating stimulation, revealing that an intrinsic limit to proliferation exists even under these conditions. This limit was linked directly to division number rather than time of exposure to stimulation and operated independently of the survival regulation of the cells. These results demonstrate that a B cell population's division destiny is regulable by the stimulatory conditions up to an inherent maximum value. Division destiny is a crucial parameter in regulating the extent of B cell responses and thereby also the nature of the immune response mounted.
Mass and Reliability System (MaRS)
NASA Technical Reports Server (NTRS)
Barnes, Sarah
2016-01-01
The Safety and Mission Assurance (S&MA) Directorate is responsible for mitigating risk, providing system safety, and lowering risk for space programs from ground to space. The S&MA is divided into 4 divisions: The Space Exploration Division (NC), the International Space Station Division (NE), the Safety & Test Operations Division (NS), and the Quality and Flight Equipment Division (NT). The interns, myself and Arun Aruljothi, will be working with the Risk & Reliability Analysis Branch under the NC Division's. The mission of this division is to identify, characterize, diminish, and communicate risk by implementing an efficient and effective assurance model. The team utilizes Reliability and Maintainability (R&M) and Probabilistic Risk Assessment (PRA) to ensure decisions concerning risks are informed, vehicles are safe and reliable, and program/project requirements are realistic and realized. This project pertains to the Orion mission, so it is geared toward a long duration Human Space Flight Program(s). For space missions, payload is a critical concept; balancing what hardware can be replaced by components verse by Orbital Replacement Units (ORU) or subassemblies is key. For this effort a database was created that combines mass and reliability data, called Mass and Reliability System or MaRS. The U.S. International Space Station (ISS) components are used as reference parts in the MaRS database. Using ISS components as a platform is beneficial because of the historical context and the environment similarities to a space flight mission. MaRS uses a combination of systems: International Space Station PART for failure data, Vehicle Master Database (VMDB) for ORU & components, Maintenance & Analysis Data Set (MADS) for operation hours and other pertinent data, & Hardware History Retrieval System (HHRS) for unit weights. MaRS is populated using a Visual Basic Application. Once populated, the excel spreadsheet is comprised of information on ISS components including: operation hours, random/nonrandom failures, software/hardware failures, quantity, orbital replaceable units (ORU), date of placement, unit weight, frequency of part, etc. The motivation for creating such a database will be the development of a mass/reliability parametric model to estimate mass required for replacement parts. Once complete, engineers working on future space flight missions will have access a mean time to failures and on parts along with their mass, this will be used to make proper decisions for long duration space flight missions
Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-16
... Print Works Company, Webster Division, Webster, MA; Cranston Print Works Company, Corporate Offices..., 2009, applicable to workers of Cranston Print Works Company, Webster Division, Webster, Massachusetts... certification to include workers from Cranston Print Works Company, Corporate Offices, Cranston, Rhode Island...
Rivkin, Richard B.
1986-01-01
Silicon is an essential element for diatom frustule synthesis and is usually taken up only by dividing cells. With 68Ge, a radioactive analog of Si, the cell cycle marker event of frustule formation was identified for individual species of diatom. The frequency of cells within a population undergoing this division event was estimated, and the cell division rate was calculated. In laboratory cultures, these rates of cell division and those calculated from changes in cell numbers were similar. By dual labeling with 68Ge(OH)4 and NaH14CO3, rates of cell division and photosynthesis were coincidently measured for diatoms both in laboratory cultures and when isolated from natural populations in estuarine, offshore, and polar environments. These techniques permit the coupling between photosynthesis and cell division to be examined in situ for individual species of diatom. PMID:16347039
We Cannot Walk Away: DEC's Position of Child Abuse, Neglect, and Trauma
ERIC Educational Resources Information Center
Corr, Catherine
2016-01-01
This article details two important reasons why supporting young children with disabilities who have experienced abuse and neglect and their families is the responsibility and obligation of the Division for Early Childhood of the Council for Exceptional Children (DEC): (1) Although prevalent in their work, this population is overlooked; and (2)…
State Estimates of Organized Child Care Facilities. Population Division Working Paper Series No. 21.
ERIC Educational Resources Information Center
Casper, Lynne M.; O'Connell, Martin
Census Bureau data have traditionally focused on national estimates of the numbers of children in organized child care facilities using various household surveys. In contrast, this paper presents data on the characteristics of child care businesses for individual states from the Census of Service Industries. Although focusing primarily on the most…
Work of the Bureau of Education for the Natives of Alaska. Bulletin, 1927, No. 6
ERIC Educational Resources Information Center
Hamilton, William
1927-01-01
Through its Alaska division, the United State Bureau of Education is developing and educating an aboriginal population of different races dwelling in widely varying regions and climates, many of whom require assistance in adjusting themselves to the new conditions with which civilization has confronted them. The problem involves both educating…
The Hidden Sexuality of Alexandrium Minutum: An Example of Overlooked Sex in Dinoflagellates.
Figueroa, Rosa I; Dapena, Carlos; Bravo, Isabel; Cuadrado, Angeles
2015-01-01
Dinoflagellates are haploid eukaryotic microalgae in which rapid proliferation causes dense blooms, with harmful health and economic effects to humans. The proliferation mode is mainly asexual, as the sexual cycle is believed to be rare and restricted to stressful environmental conditions. However, sexuality is key to explaining the recurrence of many dinoflagellate blooms because in many species the fate of the planktonic zygotes (planozygotes) is the formation of resistant cysts in the seabed (encystment). Nevertheless, recent research has shown that individually isolated planozygotes in the lab can enter other routes besides encystment, a behavior of which the relevance has not been explored at the population level. In this study, using imaging flow cytometry, cell sorting, and Fluorescence In Situ Hybridization (FISH), we followed DNA content and nuclear changes in a population of the toxic dinoflagellate Alexandrium minutum that was induced to encystment. Our results first show that planozygotes behave like a population with an "encystment-independent" division cycle, which is light-controlled and follows the same Light:Dark (L:D) pattern as the cycle governing the haploid mitosis. Resting cyst formation was the fate of just a small fraction of the planozygotes formed and was restricted to a period of strongly limited nutrient conditions. The diploid-haploid turnover between L:D cycles was consistent with two-step meiosis. However, the diel and morphological division pattern of the planozygote division also suggests mitosis, which would imply that this species is not haplontic, as previously considered, but biphasic, because individuals could undergo mitotic divisions in both the sexual (diploid) and the asexual (haploid) phases. We also report incomplete genome duplication processes. Our work calls for a reconsideration of the dogma of rare sex in dinoflagellates.
The Hidden Sexuality of Alexandrium Minutum: An Example of Overlooked Sex in Dinoflagellates
Figueroa, Rosa I.; Dapena, Carlos; Bravo, Isabel; Cuadrado, Angeles
2015-01-01
Dinoflagellates are haploid eukaryotic microalgae in which rapid proliferation causes dense blooms, with harmful health and economic effects to humans. The proliferation mode is mainly asexual, as the sexual cycle is believed to be rare and restricted to stressful environmental conditions. However, sexuality is key to explaining the recurrence of many dinoflagellate blooms because in many species the fate of the planktonic zygotes (planozygotes) is the formation of resistant cysts in the seabed (encystment). Nevertheless, recent research has shown that individually isolated planozygotes in the lab can enter other routes besides encystment, a behavior of which the relevance has not been explored at the population level. In this study, using imaging flow cytometry, cell sorting, and Fluorescence In Situ Hybridization (FISH), we followed DNA content and nuclear changes in a population of the toxic dinoflagellate Alexandrium minutum that was induced to encystment. Our results first show that planozygotes behave like a population with an “encystment-independent” division cycle, which is light-controlled and follows the same Light:Dark (L:D) pattern as the cycle governing the haploid mitosis. Resting cyst formation was the fate of just a small fraction of the planozygotes formed and was restricted to a period of strongly limited nutrient conditions. The diploid-haploid turnover between L:D cycles was consistent with two-step meiosis. However, the diel and morphological division pattern of the planozygote division also suggests mitosis, which would imply that this species is not haplontic, as previously considered, but biphasic, because individuals could undergo mitotic divisions in both the sexual (diploid) and the asexual (haploid) phases. We also report incomplete genome duplication processes. Our work calls for a reconsideration of the dogma of rare sex in dinoflagellates. PMID:26599692
Work management plan for data systems and analysis directorate
NASA Technical Reports Server (NTRS)
Nichols, L. R.
1979-01-01
A contract with the Data Systems and Analysis Directorate contains a specified level of resources related to a specific set of work in support of three divisions within the Data Systems and Analysis Directorate. The divisions are Institutional Data Systems Division, Ground Data Systems Division, and Mission Planning and Analysis Division. The Statement of work defines at a functional requirements level the type of support to be provided to the three divisions. The contract provides for further technical direction to the contractor through issuance of Job Orders. The Job order is the prime method of further defining the work to be done, allocating a portion of the total resources in the contract to the defined tasks, and further delegating technical responsibility.
ERIC Educational Resources Information Center
Obura, Willis Bill
Rural Africa includes some 80% of the African population; its people are poverty stricken, illiterate, ill-sheltered, and ill-nourished. These circumstances make rural development absolutely vital. However, past rural development policies have failed to take into consideration the structure and division of labor in the farm family, the traditional…
On modeling complex interplay in small-scale self-organized socio-hydrological systems
NASA Astrophysics Data System (ADS)
Muneepeerakul, Rachata
2017-04-01
Successful and sustainable socio-hydrological systems, as in any coupled natural human-systems, require effective governance, which depends on the existence of proper infrastructure (both hard and soft). Recent work has addressed systems in which resource users and the organization responsible for maintaining the infrastructure are separate entities. However, many socio-hydrological systems, especially in developing countries, are small and without such formal division of labor; rather, such division of labor typically arises from self-organization within the population. In this work, we modify and mathematically operationalize a conceptual framework by developing a system of differential equations that capture the strategic behavior within such a self-organized population, its interplay with infrastructure characteristics and hydrological dynamics, and feedbacks between these elements. The model yields a number of insightful conditions related to long-term sustainability and collapse of the socio-hydrological system in the form of relationships between biophysical and social factors. These relationships encapsulate nonlinear interactions of these factors. The modeling framework is grounded in a solid conceptual foundation upon which additional modifications and realism can be built for potential reconciliation between socio-hydrology with other related fields and further applications.
Carrick, Danielle M; Mette, Eliza; Hoyle, Brittany; Rogers, Scott D; Gillanders, Elizabeth M; Schully, Sheri D; Mechanic, Leah E
2014-08-01
Over the past two decades, researchers have increasingly used human biospecimens to evaluate hypotheses related to disease risk, outcomes and treatment. We conducted an analysis of population-science cancer research grants funded by the National Cancer Institute (NCI) to gain a more comprehensive understanding of biospecimens and common derivatives involved in those studies and identify opportunities for advancing the field. Data available for 1,018 extramural, peer-reviewed grants (active as of July 2012) supported by the Division of Cancer Control and Population Sciences (DCCPS), the NCI Division that supports cancer control and population-science extramural research grants, were analyzed. 455 of the grants were determined to involve biospecimens or derivatives. The most common specimen types included were whole blood (51% of grants), serum or plasma (40%), tissue (39%), and the biospecimen derivative, DNA (66%). While use of biospecimens in molecular epidemiology has become common, biospecimens for behavioral and social research is emerging, as observed in our analysis. Additionally, we found the majority of grants were using already existing biospecimens (63%). Grants that involved use of existing biospecimens resulted in lower costs (studies that used existing serum/plasma biospecimens were 4.2 times less expensive) and more publications per year (1.4 times) than grants collecting new biospecimens. This analysis serves as a first step at understanding the types of biospecimen collections supported by NCI DCCPS. There is room to encourage increased use of archived biospecimens and new collections of rarer specimen and cancer types, as well as for behavioral and social research. To facilitate these efforts, we are working to better catalogue our funded resources and make that data available to the extramural community.
Fone, David; Jones, Andrew; Watkins, John; Lester, Nathan; Cole, Jane; Thomas, Gary; Webber, Margaret; Coyle, Edward
2002-01-01
BACKGROUND: Primary care organisations in the United Kingdom have been given new and challenging population health responsibilities to improve health and address health inequality in local communities through partnership working with local authorities. This requires robust health and social needs assessment data for effective local planning. AIM: To assess the use and value of local authority data shared through partnership working between Caerphilly Local Health Group and Caerphilly County Borough Council. DESIGN OF STUDY: Cross-sectional analysis of aggregate electoral division data. SETTING: Caephilly County Borough, south-east Wales. METHOD: Local authority datasets identified were categorised into one of six domains: income, unemployment, housing, health, education, and social services. Data were presented at electoral division level as rates in thematic maps and correlations between the variables within and between each domain were explored using Spearman's rank correlation coefficient, with particular focus on children in families. Local planning documents were scrutinised to ascertain the use and value of the data. RESULTS: A broad range of data described a comprehensive picture of health and social inequalities within the borough. Multiple deprivation tended to cluster in electoral divisions, particularly for data relating to children, painting an overwhelming picture of inequality in life chances. The data were used in a wide range of local partnership planning initiatives, including the Health Improvement Programme, Children's Services Plan, and a successful Healthy Living Centre bid. CONCLUSION: Local authority data can help primary care organisations in a population approach to needs assessment for use in local partnership planning targeted at reducing health inequalities. PMID:12392118
A new focus for the International Cancer Screening Network
The ICSN is thinking about how to take advantage of the nearly three decades of work in cancer screening program research and implementation and reach out more actively to low- and middle-income countries considering screening. For that purpose, ICSN is migrating from its historical place under NCI Division of Cancer Control and Population Sciences to assume its new role within the Center for Global Health.
Kvitko, O V; Koneva, I I; Sheiko, Y I; Anisovich, M V
2005-12-01
The causes of the indefinite propagation of immortalized cell populations remain insufficiently understood, that hinders the research of such fundamental processes as ageing and cancer. In this study the interrelations between clonal proliferation and abnormalities of mitotic divisions in the immortalized cell line established from the mouse embryo were investigated with the aid of computerized microscopy of living cells. 3 mitoses with three daughter cells and 7 asymmetric mitoses which generated two daughter cells of conspicuously different sizes were registered among 71 mitotic divisions in the individual cell genealogy. Abnormal mitotic divisions either did not slow the proliferation in cell clones compared with progenies of cells that divided by means of normal mitoses or were followed by the acceleration of divisions in consecutive cell generations. These data suggest that abnormal mitotic divisions may contribute to the maintenance of the immortalized state of cell populations by means of generating chromosomal instability.
NASA Technical Reports Server (NTRS)
Cai, Li; Hayes, Nancy L.; Takahashi, Takao; Caviness, Verne S Jr; Nowakowski, Richard S.
2002-01-01
Mechanisms that regulate neuron production in the developing mouse neocortex were examined by using a retroviral lineage marking method to determine the sizes of the lineages remaining in the proliferating population of the ventricular zone during the period of neuron production. The distribution of clade sizes obtained experimentally in four different injection-survival paradigms (E11-E13, E11-E14, E11-E15, and E12-E15) from a total of over 500 labeled lineages was compared with that obtained from three models in which the average behavior of the proliferating population [i.e., the proportion of cells remaining in the proliferative population (P) vs. that exiting the proliferative population (Q)] was quantitatively related to lineage size distribution. In model 1, different proportions of asymmetric, symmetric terminal, and symmetric nonterminal cell divisions coexisted during the entire developmental period. In model 2, the developmental period was divided into two epochs: During the first, asymmetric and symmetric nonterminal cell divisions occurred, but, during the second, asymmetric and symmetric terminal cell divisions occurred. In model 3, the shifts in P and Q are accounted for by changes in the proportions of the two types of symmetric cell divisions without the inclusion of any asymmetric cell divisions. The results obtained from the retroviral experiments were well accounted for by model 1 but not by model 2 or 3. These findings demonstrate that: 1) asymmetric and both types of symmetric cell divisions coexist during the entire period of neurogenesis in the mouse, 2) neuron production is regulated in the proliferative population by the independent decisions of the two daughter cells to reenter S phase, and 3) neurons are produced by both asymmetric and symmetric terminal cell divisions. In addition, the findings mean that cell death and/or tangential movements of cells in the proliferative population occur at only a low rate and that there are no proliferating lineages "reserved" to make particular laminae or cell types. Copyright 2002 Wiley-Liss, Inc.
Social Work-Business Sector Collaboration in Pursuit of Economic Justice.
Lee, Wonhyung
2016-07-01
This article examines social workers' perceptions, experiences, and prospects regarding working in the business sector after participating in an MSW field practicum with a local microlending program. Social workers' insights suggest that cross-sector collaboration leads to vast opportunities not only for the populations served by the collaborative efforts, but also for social work as a profession. However, several challenges are evealed, including social workers' unfamiliarity with business operations, the business sector's narrow understanding of social workers' roles, and divisions between participants in interprofessional collaboration. This article calls for enhancing the role of social work to maximize its impact on economic development through further research and tangible cross-sector projects.
Sato, Andrea Toshye; Barros, Juliana de Oliveira; Jardim, Tatiana de Andrade; Ratier, Ana Paula Pelegrini; Lancman, Selma
2017-11-06
This study aimed to identify and analyze the relations between aging and work. This was a case study in the maintenance engineering division of a high-complexity hospital in the city of São Paulo, Brazil. In September and October 2015, 16 semi-structured interviews were held with the division heads and other workers with a minimum age of 50 years. The data were analyzed with thematic content analysis. Although the workers experienced difficulties resulting from the aging process, these did not prevent them from performing their work activities, since they developed strategies through their knowhow to compensate for their functional losses and/or declines. Still, they felt limited and demotivated due to the poor working conditions, outsourcing of the division, and the prevailing workload organization. Thus, in this division, the working conditions and organization had more impact than the aging process on the individuals' daily work routine.
Dugenia, M E
1982-12-01
The goal of the Philippine Population Education Program (PEP) since its inception in 1972 is to institutionalize population education in the formal educational system. The PEP Training Section views institutionalization of population education in the inservice education program for elementary school teachers as part of the process of making it an integral part of that program. In practice elementary school teachers periodically attend training programs organized by division or district supervisors and school principals. This is the usual modality through which teachers are updated on or informed about new thrusts and recent developments in teaching content, strategies, and methodologies. In this context, the PEP Training Section convened a seminar workshop in December 1981 for 10 subject area supervisors from the 3 large geographic island groups of Luzon, Visayas, and Mindanao. They represented 10 school divisions and subject areas where population education is integrated. The specific objectives of the 5 day activity were to: discuss existing inservice training programs in the school divisions; prepare a training model incorporating population education in the overall division inservice training program; and develop a content chart or a listing of topical areas on population education for the training model. 1 of the outputs of the seminar workshop was a training model incorporating population education in the regular inservice training programs using 3 delivery schemes, i.e., seminar workship on the teaching of specific subject areas; district staff meeting and/or echo seminars organized by district supervisors following division seminars; and regular teachers' meeting at the school level organized by school principals. Another output was a content chart listing suggested topics in population education classified according to subject areas into which they will be incorporated. The semninar workshop concluded with a plan to try out the model using the identified modalities in respective school divisions during the year 1982 and an agreement to reconvene for a feedback conference after the tryout. During the feedback conference held in August 1982, certain factors that are critical for the institutionalization of population education in the inservice training programs for teachers were identified: need for support of the top officials of the school division; need for diffusion of the training to other subject areas; and need for involvement of the supervisory hierarchy. The pilot experience showed that involvement of the supervisory hierarchy in charge of training of teachers in planning and organization of inservice training programs facilitates training and articulates and corrdinates training management.
Lavander, Päivi; Meriläinen, Merja; Turkki, Leena
2016-11-01
This systematic review aimed to synthesise the existing evidence of working time use and the division of labour among nurses and health-care workers in hospital wards. The environment of nursing work is changing. Health systems are becoming more complex and costly, and highly skilled health-care professionals are transferring to new, more demanding tasks. Changes require a division of labour that is based on the efficient use of working time. Sixteen studies were identified for the final analysis through a systematic search. The use of working time was examined mainly through six categories: direct care, indirect care, documentation, unit-related work, personal time and non-nursing duties. The division of labour was examined from the perspective of different occupational groups. Despite nurses' different educational backgrounds, certain similarities could be observed. All working groups seem to spend less than half of their working time in direct patient care. Nurse managers could influence the increasing nursing workload by supporting the right division of labour and focusing the nurses' working time use so that it benefits the patient. © 2016 John Wiley & Sons Ltd.
Receptor-mediated Drp1 oligomerization on endoplasmic reticulum
Ji, Wei-Ke; Fan, Xintao; Strack, Stefan
2017-01-01
Drp1 is a dynamin guanosine triphosphatase important for mitochondrial and peroxisomal division. Drp1 oligomerization and mitochondrial recruitment are regulated by multiple factors, including interaction with mitochondrial receptors such as Mff, MiD49, MiD51, and Fis. In addition, both endoplasmic reticulum (ER) and actin filaments play positive roles in mitochondrial division, but mechanisms for their roles are poorly defined. Here, we find that a population of Drp1 oligomers is associated with ER in mammalian cells and is distinct from mitochondrial or peroxisomal Drp1 populations. Subpopulations of Mff and Fis1, which are tail-anchored proteins, also localize to ER. Drp1 oligomers assemble on ER, from which they can transfer to mitochondria. Suppression of Mff or inhibition of actin polymerization through the formin INF2 significantly reduces all Drp1 oligomer populations (mitochondrial, peroxisomal, and ER bound) and mitochondrial division, whereas Mff targeting to ER has a stimulatory effect on division. Our results suggest that ER can function as a platform for Drp1 oligomerization, and that ER-associated Drp1 contributes to mitochondrial division. PMID:29158231
Cell-Division Behavior in a Heterogeneous Swarm Environment.
Erskine, Adam; Herrmann, J Michael
2015-01-01
We present a system of virtual particles that interact using simple kinetic rules. It is known that heterogeneous mixtures of particles can produce particularly interesting behaviors. Here we present a two-species three-dimensional swarm in which a behavior emerges that resembles cell division. We show that the dividing behavior exists across a narrow but finite band of parameters and for a wide range of population sizes. When executed in a two-dimensional environment the swarm's characteristics and dynamism manifest differently. In further experiments we show that repeated divisions can occur if the system is extended by a biased equilibrium process to control the split of populations. We propose that this repeated division behavior provides a simple model for cell-division mechanisms and is of interest for the formation of morphological structure and to swarm robotics.
Gutacker, Michaela; Conza, Nadine; Benagli, Cinzia; Pedroli, Ambra; Bernasconi, Marco Valerio; Permin, Lise; Aznar, Rosa; Piffaretti, Jean-Claude
2003-06-01
Genetic relationships among 62 Vibrio vulnificus strains of different geographical and host origins were analyzed by multilocus enzyme electrophoresis (MLEE), random amplification of polymorphic DNA (RAPD), and sequence analyses of the recA and glnA genes. Out of 15 genetic loci analyzed by MLEE, 11 were polymorphic. Cluster analysis identified 43 distinct electrophoretic types (ETs) separating the V. vulnificus population into two divisions (divisions I and II). One ET (ET 35) included all indole-negative isolates from diseased eels worldwide (biotype 2). A second ET (ET 2) marked all of the strains from Israel isolated from patients who handled St. Peter's fish (biotype 3). RAPD analysis of the 62 V. vulnificus isolates identified 26 different profiles separated into two divisions as well. In general, this subdivision was comparable (but not identical) to that observed by MLEE. Phylogenetic analysis of 543 bp of the recA gene and of 402 bp of the glnA gene also separated the V. vulnificus population into two major divisions in a manner similar to that by MLEE and RAPD. Sequence data again indicated the overall subdivision of the V. vulnificus population into different biotypes. In particular, indole-negative eel-pathogenic isolates (biotype 2) on one hand and the Israeli isolates (biotype 3) on the other tended to cluster together in both gene trees. None of the methods showed an association between distinct clones and human clinical manifestations. Furthermore, except for the Israeli strains, only minor clusters comprising geographically related isolates were observed. In conclusion, all three approaches (MLEE, RAPD, and DNA sequencing) generated comparable but not always equivalent results. The significance of the two divisions (divisions I and II) still remains to be clarified, and a reevaluation of the definition of the biotypes is also needed.
Rodriguez, Guadalupe; Trejo, Grisel; Schiemann, Elizabeth; Quandt, Sara A; Daniel, Stephanie S; Sandberg, Joanne C; Arcury, Thomas A
2016-06-01
This analysis describes the work organization and domestic work experienced by migrant Latinas, and explores the linkage between work and health. Twenty Latina workers in North Carolina with at least one child under age 12 completed in-depth interviews focused on their work organization, domestic responsibilities, work-family conflict, health, and family health. Using a systematic qualitative analysis, these women described a demanding work organization that is contingent and exploitative, with little control or support. They also described demanding domestic roles, with gendered and unequal division of household work. The resulting work-family conflict affects their mental and physical health, and has negative effects on the care and health of their families. The findings from this study highlight that work stressors from an unfavorable work organization create work-family conflict, and that work-family conflict in this population has a negative influence on workers' health and health behaviors.
NASA Astrophysics Data System (ADS)
Baublitz, C. B.; Henderson, B. H.; Pachon, J. E.; Galvis, B. R.
2014-12-01
Colombia has strict economic divisions, which may be represented by six strata assigned by the National Planning Department. These are assigned by housing conditions and are arranged such that the divisions with subpar living conditions (strata levels one through three) may receive support from those with better than acceptable living conditions (strata levels five and six). Notably, division three no longer receives aid, and division four neither contributes to this system nor receives support. About ten percent of the population is in the upper three strata, while the remaining populace experiences subpar living conditions. Bogotá, DC has poor air quality that sometimes puts sensitive populations at risk due to particulate matter (PM). The local environmental agency has developed seven strategies to reduce air pollution, predominantly by regulating fixed and mobile sources, for the promotion of public health. Preliminary mapping of results indicates there may be higher concentrations of pollutants in areas whose residents are of a lower socioeconomic status (SES). Because it's more difficult for impoverished people to miss work or afford healthcare, higher exposure could have more significance for the city's overall health burden. The aim of this project is to determine the effective impactful regulatory strategy for the benefit of public health as a result of emission reductions. This will be done by using CMAQ results and BenMAP with information for long-term relative risk estimates for PM to find premature mortality rates per source type and location, segregated by strata division. A statistical regression will define the correspondence between health impact and SES. The benefit per reduction will be given in premature mortalities avoided per ton of PM emissions reduced per source type. For each of seven proposed regulatory strategies, this project provides results in mortalities avoided per ton of emissions of PM reduced per source type. It also compares these results against the strata divisions to analyze the correspondence between SES and exposure to air pollution. Because there are many industrial facilities close to residential areas of the lower three strata, it's predicted that fixed sources are the main contributor to health impacts for citizens of a lower SES.
Harrison, Rebecca A; Gregg, Jessica L
2009-01-01
Increasing numbers of clinicians desire part-time work, and many will opt out of academic medicine if the barriers to part-time work are too great. Purposeful sampling was used to investigate the experiences of part-time academic physicians and their division leaders to understand (1) how each identified the negative and positive consequences of part-time work, and (2) how each conceptualize part-time work. In 2004, the authors interviewed the Society of General Medicine Horn Scholars Program applicants and their division chiefs from the 2001 and 2004 award cycles and performed a qualitative analysis of the one- to two-hour audiotaped interviews. Seven out of nine eligible applicants and six of seven division chiefs participated. All applicants were female junior faculty clinician educators in academic internal medicine from seven institutions. All division chiefs were male full-time faculty members. Both applicants and division chiefs identified multiple specific negative and positive consequences of part-time work. Analysis of interviews suggested that both groups tended to frame part-time work as a decision to "work less" or to "work differently." Self-reflection and articulation of values helped some faculty determine where they derive the greatest happiness and fulfillment personally and professionally. As more academics seek work-life balance and consider part-time work as a tool to achieve that balance, academic medicine will be challenged to develop creative models for integrating successful part-time physicians, or it will lose that segment of the workforce. This study's findings suggest that one such model may require that physicians and their leaders reconceptualize work altogether.
Reconsidering the Division of Household Labor: Incorporating Volunteer Work and Informal Support
ERIC Educational Resources Information Center
L. Hook, Jennifer
2004-01-01
The gendered division of household labor is more multifaceted than the allocation of paid work and domestic work. People also engage in volunteer work and informal support. I investigate the applicability of household labor allocation theories - specifically the time constraints, economic, and doing gender perspectives - to all unpaid work. I…
Whatever Works: A Test of the "Division of Labor" Component of Uses and Gratifications Theory.
ERIC Educational Resources Information Center
Carvalho, John
The 1974 book, "The Uses of Mass Communication: Current Perspectives on Gratifications Research" introduced the concept of a "division of labor"--that certain media work better than others in meeting audience gratifications. Since the division of labor concept has not been subjected to empirical testing, a study elaborated an…
Lee, Calvin K; Kim, Alexander J; Santos, Giancarlo S; Lai, Peter Y; Lee, Stella Y; Qiao, David F; Anda, Jaime De; Young, Thomas D; Chen, Yujie; Rowe, Annette R; Nealson, Kenneth H; Weiss, Paul S; Wong, Gerard C L
2016-09-06
Cell size control and homeostasis are fundamental features of bacterial metabolism. Recent work suggests that cells add a constant size between birth and division ("adder" model). However, it is not known how cell size homeostasis is influenced by the existence of heterogeneous microenvironments, such as those during biofilm formation. Shewanella oneidensis MR-1 can use diverse energy sources on a range of surfaces via extracellular electron transport (EET), which can impact growth, metabolism, and size diversity. Here, we track bacterial surface communities at single-cell resolution to show that not only do bacterial motility appendages influence the transition from two- to three-dimensional biofilm growth and control postdivisional cell fates, they strongly impact cell size homeostasis. For every generation, we find that the average growth rate for cells that stay on the surface and continue to divide (nondetaching population) and that for cells that detach before their next division (detaching population) are roughly constant. However, the growth rate distribution is narrow for the nondetaching population, but broad for the detaching population in each generation. Interestingly, the appendage deletion mutants (ΔpilA, ΔmshA-D, Δflg) have significantly broader growth rate distributions than that of the wild type for both detaching and nondetaching populations, which suggests that Shewanella appendages are important for sensing and integrating environmental inputs that contribute to size homeostasis. Moreover, our results suggest multiplexing of appendages for sensing and motility functions contributes to cell size dysregulation. These results can potentially provide a framework for generating metabolic diversity in S. oneidensis populations to optimize EET in heterogeneous environments.
Worklife and Wellness in Academic General Internal Medicine: Results from a National Survey.
Linzer, Mark; Poplau, Sara; Babbott, Stewart; Collins, Tracie; Guzman-Corrales, Laura; Menk, Jeremiah; Murphy, Mary Lou; Ovington, Kay
2016-09-01
General internal medicine (GIM) careers are increasingly viewed as challenging and unsustainable. We aimed to assess academic GIM worklife and determine remediable predictors of stress and burnout. We conducted an email survey. Physicians, nurse practitioners, and physician assistants in 15 GIM divisions participated. A ten-item survey queried stress, burnout, and work conditions such as electronic medical record (EMR) challenges. An open-ended question assessed stressors and solutions. Results were categorized into burnout, high stress, high control, chaos, good teamwork, high values alignment, documentation time pressure, and excessive home EMR use. Frequencies were determined for national data, Veterans Affairs (VA) versus civilian populations, and hospitalist versus ambulatory roles. A General Linear Mixed Model (GLMM) evaluated associations with burnout. A formal content analysis was performed for open-ended question responses. Of 1235 clinicians sampled, 579 responded (47 %). High stress was present in 67 %, with 38 % burned out (burnout range 10-56 % by division). Half of respondents had low work control, 60 % reported high documentation time pressure, half described too much home EMR time, and most reported very busy or chaotic workplaces. Two-thirds felt aligned with departmental leaders' values, and three-quarters were satisfied with teamwork. Burnout was associated with high stress, low work control, and low values alignment with leaders (all p < 0.001). The 45 VA faculty had less burnout than civilian counterparts (17 % vs. 40 %, p < 0.05). Hospitalists described better teamwork than ambulatory clinicians and fewer hospitalists noted documentation time pressure (both p < 0.001). Key themes from the qualitative analysis were short visits, insufficient support staff, a Relative Value Unit mentality, documentation time pressure, and undervaluing education. While GIM divisions overall demonstrate high stress and burnout, division rates vary widely. Sustainability efforts within GIM could focus on visit length, staff support, schedule control, clinic chaos, and EMR stress.
ADP Analysis project for the Human Resources Management Division
NASA Technical Reports Server (NTRS)
Tureman, Robert L., Jr.
1993-01-01
The ADP (Automated Data Processing) Analysis Project was conducted for the Human Resources Management Division (HRMD) of NASA's Langley Research Center. The three major areas of work in the project were computer support, automated inventory analysis, and an ADP study for the Division. The goal of the computer support work was to determine automation needs of Division personnel and help them solve computing problems. The goal of automated inventory analysis was to find a way to analyze installed software and usage on a Macintosh. Finally, the ADP functional systems study for the Division was designed to assess future HRMD needs concerning ADP organization and activities.
Division I Men's Basketball Scholarship: The Challenges of Being a Black Male Athlete
ERIC Educational Resources Information Center
Wright, Lonnie
2015-01-01
The Qualitative research will explore issues that interface particularly with Black student- athletes on Division 1 basketball scholarships regarding academic readiness, academic support, family support and how the experience of a Division 1 scholarship impacted their lives. The population of Black student-athletes that the focus of the research…
Towards understanding and managing the learning process in mail sorting.
Berglund, M; Karltun, A
2012-01-01
This paper was based on case study research at the Swedish Mail Service Division and it addresses learning time to sort mail at new districts and means to support the learning process on an individual as well as organizational level. The study population consisted of 46 postmen and one team leader in the Swedish Mail Service Division. Data were collected through measurements of time for mail sorting, interviews and a focus group. The study showed that learning to sort mail was a much more complex process and took more time than expected by management. Means to support the learning process included clarification of the relationship between sorting and the topology of the district, a good work environment, increased support from colleagues and management, and a thorough introduction for new postmen. The identified means to support the learning process require an integration of human, technological and organizational aspects. The study further showed that increased operations flexibility cannot be reinforced without a systems perspective and thorough knowledge about real work activities and that ergonomists can aid businesses to acquire this knowledge.
The finite state projection approach to analyze dynamics of heterogeneous populations
NASA Astrophysics Data System (ADS)
Johnson, Rob; Munsky, Brian
2017-06-01
Population modeling aims to capture and predict the dynamics of cell populations in constant or fluctuating environments. At the elementary level, population growth proceeds through sequential divisions of individual cells. Due to stochastic effects, populations of cells are inherently heterogeneous in phenotype, and some phenotypic variables have an effect on division or survival rates, as can be seen in partial drug resistance. Therefore, when modeling population dynamics where the control of growth and division is phenotype dependent, the corresponding model must take account of the underlying cellular heterogeneity. The finite state projection (FSP) approach has often been used to analyze the statistics of independent cells. Here, we extend the FSP analysis to explore the coupling of cell dynamics and biomolecule dynamics within a population. This extension allows a general framework with which to model the state occupations of a heterogeneous, isogenic population of dividing and expiring cells. The method is demonstrated with a simple model of cell-cycle progression, which we use to explore possible dynamics of drug resistance phenotypes in dividing cells. We use this method to show how stochastic single-cell behaviors affect population level efficacy of drug treatments, and we illustrate how slight modifications to treatment regimens may have dramatic effects on drug efficacy.
ERIC Educational Resources Information Center
Carter, Christina Michelle
2012-01-01
Division I intercollegiate student-athletes represent a unique population of college students on college campuses today because they face competing demands between the student and athlete roles. Without the proper environment and motivation for academic performance, some Division I student-athletes are unable to obtain a college degree and leave…
Joy Osborne, MS, MPA | Division of Cancer Prevention
Joy Osborne is the ARC Director for the Division of Cancer Prevention and the Division of Cancer Control and Population Sciences. The ARC (Administrative Resource Center) provides services to DCP in the areas of budget, contracts, grants, human resources, travel, space and facilities, and other administrative areas. Joy came to NCI in 1992 as a Presidential Management Intern
ERIC Educational Resources Information Center
Gunter, Nancy C.; Gunter, B. G.
This study examined the relationship of gender, sex role orientation, and work attitudes to the domestic division of labor in 141 working couples. Couples completed the Bem Sex Role Inventory and a questionnaire on the performance of household tasks. Analysis of variance (ANOVA) confirmed that working women performed a disproportionately larger…
ERIC Educational Resources Information Center
International Federation of Library Associations and Institutions, London (England).
Eleven papers delivered for the Division of Libraries Serving the General Public at the International Federation of Library Associations and Institutions 1992 annual meeting are presented. Most deal with library services to multicultural populations, including those of developing countries. The following papers are included: (1) "Library…
Chen, Lingyun; Wu, Weining; El-Serehy, Hamed A; Hu, Xiaozhong; Clamp, John C
2018-04-30
A distinct population of Anteholosticha intermedia was isolated from soil in the Great Smoky Mountains of North Carolina, USA, and its morphology, morphogenesis and molecular phylogeny investigated by microscopic observations of live and protargol-prepared specimens and analyses of the sequence of small subunit (SSU) rDNA. Our population closely resembles the populations from Austria and Korea. Members of the genus Anteholosticha have been regarded as ontogenetically diverse, which is confirmed by the present work. The most noteworthy ontogenetic feature of the American population of A. intermedia is that the oral primordium in the proter appears apokinetally at the posterior end of the undulating membranes anlage at the beginning of division and then dedifferentiates midway through morphogenesis. Molecular phylogenetic analyses demonstrate, with high support, that the American population of A. intermedia is clearly distinct from congeners and branches as part of a sister lineage to the Bakuella-Urostyla clade that belongs to the major clade comprising the order Urostylida. Copyright © 2018 Elsevier GmbH. All rights reserved.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-21
... to working in the nuclear industry for workers coming in without nuclear experience; New Hire... employees in its Nuclear Services (i.e., construction) and Nuclear Maintenance Divisions working at nuclear... (i.e., construction) and Nuclear Maintenance Divisions working at nuclear facilities addressing: (a...
On the Unsteady-Motion Theory of Magnetic Forces for Maglev
1993-11-01
DivisionEnergy Technology Division Forces for Maglev Energy Technology DivisionEnergy Technology Division by S. S. Chen, S. Zhu, and Y. Cai APQ 4 袲...On the Unsteady-Motion Theory of Magnetic Forces for Maglev by S. S. Chen, S. Zhu, and Y. Cai Energy Technology Division November 1993 Work supported...vi On The Unsteady-Motion Theory of Magnetic Forces for Maglev by S. S
Division G Commission 35: Stellar Constitution
NASA Astrophysics Data System (ADS)
Limongi, Marco; Lattanzio, John C.; Charbonnel, Corinne; Dominguez, Inma; Isern, Jordi; Karakas, Amanda; Leitherer, Claus; Marconi, Marcella; Shaviv, Giora; van Loon, Jacco
2016-04-01
Commission 35 (C35), ``Stellar Constitution'', consists of members of the International Astronomical Union whose research spans many aspects of theoretical and observational stellar physics and it is mainly focused on the comprehension of the properties of stars, stellar populations and galaxies. The number of members of C35 increased progressively over the last ten years and currently C35 comprises about 400 members. C35 was part of Division IV (Stars) until 2014 and then became part of Division G (Stars and Stellar Physics), after the main IAU reorganisation in 2015. Four Working Groups have been created over the years under Division IV, initially, and Division G later: WG on Active B Stars, WG on Massive Stars, WG on Abundances in Red Giant and WG on Chemically Peculiar and Related Stars. In the last decade the Commission had 4 presidents, Wojciech Dziembowski (2003-2006), Francesca D'Antona (2006-2009), Corinne Charbonnel (2009-2012) and Marco Limongi (2012-2015), who were assisted by an Organizing Committee (OC), usually composed of about 10 members, all of them elected by the C35 members and holding their positions for three years. The C35 webpage (http://iau-c35.stsci.edu) has been designed and continuously maintained by Claus Leitherer from the Space Telescope Institute, who deserves our special thanks. In addition to the various general information on the Commission structure and activities, it contains links to various resources, of interest for the members, such as stellar models, evolutionary tracks and isochrones, synthetic stellar populations, stellar yields and input physics (equation of state, nuclear cross sections, opacity tables), provided by various groups. The main activity of the C35 OC is that of evaluating, ranking and eventually supporting the proposals for IAU sponsored meetings. In the last decade the Commission has supported several meetings focused on topics more or less relevant to C35. Since the primary aim of this document is to present the main activity of C35 over the last ten years, in the following we present some scientific highlights that emerged from the most relevant IAU Symposia and meetings supported and organized by C35 in the last decade.
Quantifying cell turnover using CFSE data.
Ganusov, Vitaly V; Pilyugin, Sergei S; de Boer, Rob J; Murali-Krishna, Kaja; Ahmed, Rafi; Antia, Rustom
2005-03-01
The CFSE dye dilution assay is widely used to determine the number of divisions a given CFSE labelled cell has undergone in vitro and in vivo. In this paper, we consider how the data obtained with the use of CFSE (CFSE data) can be used to estimate the parameters determining cell division and death. For a homogeneous cell population (i.e., a population with the parameters for cell division and death being independent of time and the number of divisions cells have undergone), we consider a specific biologically based "Smith-Martin" model of cell turnover and analyze three different techniques for estimation of its parameters: direct fitting, indirect fitting and rescaling method. We find that using only CFSE data, the duration of the division phase (i.e., approximately the S+G2+M phase of the cell cycle) can be estimated with the use of either technique. In some cases, the average division or cell cycle time can be estimated using the direct fitting of the model solution to the data or by using the Gett-Hodgkin method [Gett A. and Hodgkin, P. 2000. A cellular calculus for signal integration by T cells. Nat. Immunol. 1:239-244]. Estimation of the death rates during commitment to division (i.e., approximately the G1 phase of the cell cycle) and during the division phase may not be feasible with the use of only CFSE data. We propose that measuring an additional parameter, the fraction of cells in division, may allow estimation of all model parameters including the death rates during different stages of the cell cycle.
Mazerolle, Stephanie M; Eason, Christianne M
2016-07-01
Research suggests that women do not pursue leadership positions in athletic training due to a variety of reasons, including family challenges, organizational constraints, and reluctance to hold the position. The literature has been focused on the National Collegiate Athletic Association Division I setting, limiting our full understanding. To examine factors that help women as they worked toward the position of head athletic trainer. Qualitative study. Divisions II and III. Seventy-seven women who were employed as head athletic trainers at the Division II or III level participated in our study. Participants were 38 ± 9 (range = 24-57) years old and had an average of 14 ± 8 (range = 1-33) years of athletic training experience. We conducted online interviews. Participants journaled their reflections to a series of open-ended questions pertaining to their experiences as head athletic trainers. Data were analyzed using a general inductive approach. Credibility was secured by peer review and researcher triangulation. Three organizational facilitators emerged from the data, workplace atmosphere, mentors, and past work experiences. These organizational factors were directly tied to aspects within the athletic trainer's employment setting that allowed her to enter the role. One individual-level facilitator was found: personal attributes that were described as helpful for women in transitioning to the role of the head athletic trainer. Participants discussed being leaders and persisting toward their career goals. Women working in Divisions II and III experience similar facilitators to assuming the role of head athletic trainer as those working in the Division I setting. Divisions II and III were viewed as more favorable for women seeking the role of head athletic trainer, but like those in the role in the Division I setting, women must have leadership skills.
ERIC Educational Resources Information Center
Suleman, Qaiser; Gul, Rizwana
2015-01-01
The main objective of the study was to compare the teaching effectiveness of directly selected, in-service promoted and online selected subject specialists teaching at higher secondary school level in Kohat Division, Pakistan. The target population of the study was the higher secondary school students in Kohat Division, Pakistan. A sample of 600…
Identification of a new stem cell population that generates Drosophila flight muscles.
Gunage, Rajesh D; Reichert, Heinrich; VijayRaghavan, K
2014-08-18
How myoblast populations are regulated for the formation of muscles of different sizes is an essentially unanswered question. The large flight muscles of Drosophila develop from adult muscle progenitor (AMP) cells set-aside embryonically. The thoracic segments are all allotted the same small AMP number, while those associated with the wing-disc proliferate extensively to give rise to over 2500 myoblasts. An initial amplification occurs through symmetric divisions and is followed by a switch to asymmetric divisions in which the AMPs self-renew and generate post-mitotic myoblasts. Notch signaling controls the initial amplification of AMPs, while the switch to asymmetric division additionally requires Wingless, which regulates Numb expression in the AMP lineage. In both cases, the epidermal tissue of the wing imaginal disc acts as a niche expressing the ligands Serrate and Wingless. The disc-associated AMPs are a novel muscle stem cell population that orchestrates the early phases of adult flight muscle development.
Logsdon, Michelle M; Aldridge, Bree B
2018-01-01
Model bacteria, such as E. coli and B. subtilis , tightly regulate cell cycle progression to achieve consistent cell size distributions and replication dynamics. Many of the hallmark features of these model bacteria, including lateral cell wall elongation and symmetric growth and division, do not occur in mycobacteria. Instead, mycobacterial growth is characterized by asymmetric polar growth and division. This innate asymmetry creates unequal birth sizes and growth rates for daughter cells with each division, generating a phenotypically heterogeneous population. Although the asymmetric growth patterns of mycobacteria lead to a larger variation in birth size than typically seen in model bacterial populations, the cell size distribution is stable over time. Here, we review the cellular mechanisms of growth, division, and cell cycle progression in mycobacteria in the face of asymmetry and inherent heterogeneity. These processes coalesce to control cell size. Although Mycobacterium smegmatis and Mycobacterium bovis Bacillus Calmette-Guérin (BCG) utilize a novel model of cell size control, they are similar to previously studied bacteria in that initiation of DNA replication is a key checkpoint for cell division. We compare the regulation of DNA replication initiation and strategies used for cell size homeostasis in mycobacteria and model bacteria. Finally, we review the importance of cellular organization and chromosome segregation relating to the physiology of mycobacteria and consider how new frameworks could be applied across the wide spectrum of bacterial diversity.
Culture Matters: The Pivotal Role of Culture for Women’s Careers in Academic Medicine
Speck, Rebecca M.; Dupuis Sammel, Mary; Scott, Patricia; Conant, Emily F.; Tuton, Lucy Wolf; Abbuhl, Stephanie B.; Grisso, Jeane Ann
2014-01-01
Purpose Women in academic medicine are not achieving the same career advancement as men, and face unique challenges in managing work and family alongside intense work demands. The purpose of this study was to investigate how a supportive department/division culture buffered women from the impact of work demands on work-to-family conflict. Method As part of a larger intervention trial, the authors collected baseline survey data from 133 women assistant professors at the University of Pennsylvania Perelman School of Medicine in 2010. Validated measures of work demands, work-to-family conflict, and a department/division culture were employed. Pearson correlations and general linear mixed modeling were used to analyze the data. Authors investigated whether work culture moderated the association between work demands and work-to-family conflict. Results Heavy work demands were associated with increased levels of work-to-family conflict. There were significant interactions between work demands, work-to-family conflict, and department/division culture. A culture conducive to women’s academic success significantly moderated the effect of work hours on time-based work-to-family conflict and significantly moderated the effect of work overload on strain-based work-to-family conflict. At equivalent levels of work demands, women in more supportive cultures experienced lower levels of work-to-family conflict. Conclusions The culture of the department/division plays a crucial role in women’s work-to-family conflict and can exacerbate or alleviate the impact of extremely high work demands. This finding leads to important insights about strategies for more effectively supporting the careers of women assistant professors. PMID:24556773
Mazerolle, Stephanie M; Bruening, Jennifer E; Casa, Douglas J; Burton, Laura J
2008-01-01
Previous researchers have shown that work-family conflict (WFC) affects the level of a person's job satisfaction, life satisfaction, and job burnout and intentions to leave the profession. However, WFC and its consequences have not yet been fully investigated among certified athletic trainers. To investigate the relationship between WFC and various outcome variables among certified athletic trainers working in National Collegiate Athletic Association Division I-A settings. A mixed-methods design using a 53-item survey questionnaire and follow-up in-depth interviews was used to examine the prevalence of WFC. Division I-A universities sponsoring football. A total of 587 athletic trainers (324 men, 263 women) responded to the questionnaire, and 12 (6 men, 6 women) participated in the qualitative portion of the mixed-methods study. We calculated Pearson correlations to determine the relationship between WFC and job satisfaction, life satisfaction, and job burnout. Regression analyses were run to determine whether WFC was a predictor of job satisfaction, job burnout, or intention to leave the profession. Interviews were transcribed verbatim and then analyzed using the computer program N6 as well as member checks and peer debriefing. Negative relationships were found between WFC and job satisfaction (r = -.52, P < .001). Positive were noted between WFC and job burnout (r = .63, P < .001) and intention to leave the profession (r = .46, P < .001). Regression analyses revealed that WFC directly contributed to job satisfaction (P < .001), job burnout (P < .001), and intention to leave the profession (P < .001). Overall, our findings concur with those of previous researchers on WFC and its negative relationships to job satisfaction and life satisfaction and positive relationship to job burnout and intention to leave an organization. Sources of WFC, such as time, inflexible work schedules, and inadequate staffing, were also related to job burnout and job dissatisfaction in this population.
Zhang, Zheng; Milias-Argeitis, Andreas; Heinemann, Matthias
2018-02-01
Recent work has shown that metabolism between individual bacterial cells in an otherwise isogenetic population can be different. To investigate such heterogeneity, experimental methods to zoom into the metabolism of individual cells are required. To this end, the autofluoresence of the redox cofactors NADH and NADPH offers great potential for single-cell dynamic NAD(P)H measurements. However, NAD(P)H excitation requires UV light, which can cause cell damage. In this work, we developed a method for time-lapse NAD(P)H imaging in single E. coli cells. Our method combines a setup with reduced background emission, UV-enhanced microscopy equipment and optimized exposure settings, overall generating acceptable NAD(P)H signals from single cells, with minimal negative effect on cell growth. Through different experiments, in which we perturb E. coli's redox metabolism, we demonstrated that the acquired fluorescence signal indeed corresponds to NAD(P)H. Using this new method, for the first time, we report that intracellular NAD(P)H levels oscillate along the bacterial cell division cycle. The developed method for dynamic measurement of NAD(P)H in single bacterial cells will be an important tool to zoom into metabolism of individual cells.
Evaluation of health centre community nurse team.
Dixon, P N; Trounson, E
1969-02-01
This report gives an account of the work during six months of a community nurse team attached to the doctors working from a new health centre. The team consisted of two community nurses, who had both health visiting and Queen's nursing qualifications, and a State-enrolled nurse. The community nurses, in addition to undertaking all the health visiting for the population at risk, assessed the social and nursing needs of patients at the request of the general practitioners and ensured that these needs were met. When necessary they undertook practical nursing tasks in the home and in the health centre, but most of the bedside nursing in the home was done by the State-enrolled nurse.The needs of the population at risk were such that only one State-enrolled nurse could usefully be employed, and this proved to be a considerable disadvantage. Despite this, the experimental work pattern held advantages to patients, doctors, and nurses, and is potentially capable of providing a satisfying and economic division of responsibilities, with different tasks being carried out by the individual most appropriately qualified.
An analysis of the job of strength and conditioning coach for football at the Division II level.
Massey, C Dwayne; Schwind, Justin J; Andrews, Donnie C; Maneval, Mark W
2009-12-01
The purpose of this investigation was to describe the working environment of the heretofore unexamined Division II football strength and conditioning coach (SCC). Data were collected on demographic characteristics, job satisfaction, major job duties and responsibilities, work environment, and professional and personal relationships. A total of 63 questionnaires were returned by the potential 155 institutions identified at the Division II level. Percentages were used in the reporting of data. The results indicate that this group is relatively young (34.1), new to the profession, have low job stability, a low rate of professional certification, make a salary less than their Division I-A counterparts, and assume more duties and responsibilities than their Division I-A colleagues. Despite these apparent drawbacks, by and large, these SCC appeared content with their career choice and circumstances.
History of Division 29, 1993-2013: another 20 years of psychotherapy.
Williams, Elizabeth Nutt; Barnett, Jeffrey E; Canter, Mathilda B
2013-03-01
The history of Division 29 (Psychotherapy) of the American Psychological Association (APA) from 1993 to 2013 is reviewed. The 20 years of history can be traced via the Division's primary publications (the journal Psychotherapy and its newsletter Psychotherapy Bulletin) as well as the history of those who have served leadership roles in the Division and have won Divisional awards. Several recurring themes emerge related to the Division's articulations of its own identity, the Division's advocacy efforts vis-à-vis the profession and the APA, and the work of the Division on behalf of major social issues (such as disaster relief and the nation's health care).
75 FR 5145 - AK Steel Corporation, Mansfield Works Division, Mansfield, OH; Notice of Affirmative...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-02-01
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-71,375] AK Steel Corporation, Mansfield Works Division, Mansfield, OH; Notice of Affirmative Determination Regarding Application for Reconsideration By application dated December 10, 2009, the United Steel Workers, Local 169, requested...
Cell division in Escherichia coli cultures monitored at single cell resolution
Roostalu, Johanna; Jõers, Arvi; Luidalepp, Hannes; Kaldalu, Niilo; Tenson, Tanel
2008-01-01
Background A fundamental characteristic of cells is the ability to divide. To date, most parameters of bacterial cultures, including cell division, have been measured as cell population averages, assuming that all bacteria divide at a uniform rate. Results We monitored the division of individual cells in Escherichia coli cultures during different growth phases. Our experiments are based on the dilution of green fluorescent protein (GFP) upon cell division, monitored by flow cytometry. The results show that the vast majority of E. coli cells in exponentially growing cultures divided uniformly. In cultures that had been in stationary phase up to four days, no cell division was observed. However, upon dilution of stationary phase culture into fresh medium, two subpopulations of cells emerged: one that started dividing and another that did not. These populations were detectable by GFP dilution and displayed different side scatter parameters in flow cytometry. Further analysis showed that bacteria in the non-growing subpopulation were not dead, neither was the difference in growth capacity reducible to differences in stationary phase-specific gene expression since we observed uniform expression of several stress-related promoters. The presence of non-growing persisters, temporarily dormant bacteria that are tolerant to antibiotics, has previously been described within growing bacterial populations. Using the GFP dilution method combined with cell sorting, we showed that ampicillin lyses growing bacteria while non-growing bacteria retain viability and that some of them restart growth after the ampicillin is removed. Thus, our method enables persisters to be monitored even in liquid cultures of wild type strains in which persister formation has low frequency. Conclusion In principle, the approaches developed here could be used to detect differences in cell division in response to different environmental conditions and in cultures of unicellular organisms other than E. coli. PMID:18430255
Higgins, M. L.; Daneo-Moore, L.; Boothby, D.; Shockman, G. D.
1974-01-01
Selective inhibition of protein synthesis in Streptococcus faecalis (ATCC 9790) was accompanied by a rapid and severe inhibition of cell division and a reduction of enlargement of cellular surface area. Continued synthesis of cell wall polymers resulted in rapid thickening of the wall to an extent not seen in exponential-phase populations. Thus, the normal direction of wall growth was changed from a preferential feeding out of new wall surface to that of thickening existing cell surfaces. However, the overall manner in which the wall thickened, from nascent septa toward polar regions, was the same in both exponential-phase and inhibited populations. In contrast, selective inhibition of deoxyribonucleic acid (DNA) synthesis using mitomycin C was accompanied by an increase in cellular surface area and by division of about 80% of the cells in random populations. Little or no wall thickening was observed until the synthesis of macromolecules other than DNA was impaired and further cell division ceased. Concomitant inhibition of both DNA and protein synthesis inhibited cell division but permitted an increase in average cell volume. In such doubly inhibited cells, walls thickened less than in cells inhibited for protein synthesis only. On the basis of the results obtained, a model for cell surface enlargement and cell division is presented. The model proposes that: (i) each wall enlargement site is influenced by an individual chromosome replication cycle; (ii) during chromosome replication peripheral surface enlargement would be favored over thickening (or septation); (iii) a signal associated with chromosome termination would favor thickening (and septation) at the expense of surface enlargement; and (iv) a factor or signal related to protein synthesis would be required for one or more of the near terminal stages of cell division or cell separation, or both. Images PMID:4133352
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-10
..., Instrumentation and Speciality Controls Division, West Chicago, IL; Amended Certification Regarding Eligibility To... Nationals Controls Corporation, Instrumentation and Specialty Control Division, West Chicago, Illinois. The... Corporation, Instrumentation and Specialty Control Division, West Chicago, Illinois, separated from employment...
Geographic Variation in the Supply of Selected Behavioral Health Providers.
Andrilla, C Holly A; Patterson, Davis G; Garberson, Lisa A; Coulthard, Cynthia; Larson, Eric H
2018-06-01
In 2015, an estimated 43.4 million Americans aged 18 and older suffered from a behavioral health issue. Accurate estimates of the number of psychiatrists, psychologists, and psychiatric nurse practitioners are needed as demand for behavioral health care grows. The National Plan and Provider Enumeration System National Provider Identifier data (October 2015) was used to examine the supply of psychiatrists, psychologists, and psychiatric nurse practitioners. Providers were classified into three geographic categories based on their practicing county (metropolitan, micropolitan, and non-core). Claritas 2014 U.S. population data were used to calculate provider-to-population ratios for each provider type. Analysis was completed in 2016. Substantial variation exists across Census Divisions in the per capita supply of psychiatrists, psychologists, and psychiatric nurse practitioners. The New England Census Division had the highest per capita supply and the West South Central Census Division had among the lowest supply of all three provider types. Nationally, the per capita supply of these providers was substantially lower in non-metropolitan counties than in metropolitan counties, but Census Division disparities persisted across geographic categories. There was a more than tenfold difference in the percentage of counties lacking a psychiatrist between the New England Census Division (6%) and the West North Central Census Division (69%). Higher percentages of non-metropolitan counties lacked a psychiatrist. Psychiatrists, psychologists, and psychiatric nurse practitioners are unequally distributed throughout the U.S. Disparities exist across Census Divisions and geographic categories. Understanding this unequal distribution is necessary for developing approaches to improving access to behavioral health services for underserved populations. This article is part of a supplement entitled The Behavioral Health Workforce: Planning, Practice, and Preparation, which is sponsored by the Substance Abuse and Mental Health Services Administration and the Health Resources and Services Administration of the U.S. Department of Health and Human Services. Copyright © 2018 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.
The Maryland Division of Correction hospice program.
Boyle, Barbara A
2002-10-01
The Maryland Division of Correction houses 24,000 inmates in 27 geographically disparate facilities. The inmate population increasingly includes a frail, elderly component, as well as many inmates with chronic or progressive diseases. The Division houses about 900 human immunodeficiency virus (HIV)-positive detainees, almost one quarter with an acquired immune deficiency syndrome (AIDS) diagnosis. A Ryan White Special Project of National Significance (SPNS) grant and the interest of a community hospice helped transform prison hospice from idea to reality. One site is operational and a second site is due to open in the future. Both facilities serve only male inmates, who comprise more than 95% of Maryland's incarcerated. "Medical parole" is still the preferred course for terminally ill inmates; a number have been sent to various local community inpatient hospices or released to the care of their families. There will always be some who cannot be medically paroled, for whom hospice is appropriate. Maryland's prison hospice program requires a prognosis of 6 months or less to live, a do-not-resuscitate (DNR) order and patient consent. At times, the latter two of these have been problematic. Maintaining the best balance between security requirements and hospice services to dying inmates takes continual communication, coordination and cooperation. Significant complications in some areas remain: visitation to dying inmates by family and fellow prisoners; meeting special dietary requirements; what role, if any, will be played by inmate volunteers. Hospice in Maryland's Division of Correction is a work in progress.
Mazerolle, Stephanie M; Bruening, Jennifer E; Casa, Douglas J
2008-01-01
Work-family conflict (WFC) involves discord that arises when the demands of work interfere with the demands of family or home life. Long work hours, minimal control over work schedules, and time spent away from home are antecedents to WFC. To date, few authors have examined work-family conflict within the athletic training profession. To investigate the occurrence of WFC in certified athletic trainers (ATs) and to identify roots and factors leading to quality-of-life issues for ATs working in the National Collegiate Athletic Association Division I-A setting. Survey questionnaire and follow-up, in-depth, in-person interviews. Division I-A universities sponsoring football. A total of 587 ATs (324 men, 263 women) responded to the questionnaire. Twelve ATs (6 men, 6 women) participated in the qualitative portion: 2 head ATs, 4 assistant ATs, 4 graduate assistant ATs, and 2 AT program directors. Multiple regression analysis was performed to determine whether workload and travel predicted levels of WFC. Analyses of variance were calculated to investigate differences among the factors of sex, marital status, and family status. Interviews were transcribed verbatim and then analyzed using computer software as well as member checks and peer debriefing. The triangulation of the data collection and multiple sources of qualitative analysis were utilized to limit potential researcher prejudices. Regression analyses revealed that long work hours and travel directly contributed to WFC. In addition to long hours and travel, inflexible work schedules and staffing patterns were discussed by the interview participants as antecedents to WFC. Regardless of sex (P = .142), marital status (P = .687), family status (P = .055), or age of children (P = .633), WFC affected Division I-A ATs. No matter their marital or family status, ATs employed at the Division I-A level experienced difficulties balancing their work and home lives. Sources of conflict primarily stemmed from the consuming nature of the profession, travel, inflexible work schedules, and lack of full-time staff members.
The North Carolina Division of Public Health's vision for healthy and sustainable communities.
Thomas, Cathy; Rhew, Lori K; Petersen, Ruth
2012-01-01
The North Carolina Division of Public Health is working to improve access to physical activity through changes in the built environment by participating in the Healthy Environments Collaborative and by leading the state's Communities Putting Prevention to Work project and the Shape Your World movement.
Gender (in)equality among employees in elder care: implications for health.
Elwér, Sofia; Aléx, Lena; Hammarström, Anne
2012-01-04
Gendered practices of working life create gender inequalities through horizontal and vertical gender segregation in work, which may lead to inequalities in health between women and men. Gender equality could therefore be a key element of health equity in working life. Our aim was to analyze what gender (in)equality means for the employees at a woman-dominated workplace and discuss possible implications for health experiences. All caregiving staff at two workplaces in elder care within a municipality in the north of Sweden were invited to participate in the study. Forty-five employees participated, 38 women and 7 men. Seven focus group discussions were performed and led by a moderator. Qualitative content analysis was used to analyze the focus groups. We identified two themes. "Advocating gender equality in principle" showed how gender (in)equality was seen as a structural issue not connected to the individual health experiences. "Justifying inequality with individualism" showed how the caregivers focused on personalities and interests as a justification of gender inequalities in work division. The justification of gender inequality resulted in a gendered work division which may be related to health inequalities between women and men. Gender inequalities in work division were primarily understood in terms of personality and interests and not in terms of gender. The health experience of the participants was affected by gender (in)equality in terms of a gendered work division. However, the participants did not see the gendered work division as a gender equality issue. Gender perspectives are needed to improve the health of the employees at the workplaces through shifting from individual to structural solutions. A healthy-setting approach considering gender relations is needed to achieve gender equality and fairness in health status between women and men.
Gender (in)equality among employees in elder care: implications for health
2012-01-01
Introduction Gendered practices of working life create gender inequalities through horizontal and vertical gender segregation in work, which may lead to inequalities in health between women and men. Gender equality could therefore be a key element of health equity in working life. Our aim was to analyze what gender (in)equality means for the employees at a woman-dominated workplace and discuss possible implications for health experiences. Methods All caregiving staff at two workplaces in elder care within a municipality in the north of Sweden were invited to participate in the study. Forty-five employees participated, 38 women and 7 men. Seven focus group discussions were performed and led by a moderator. Qualitative content analysis was used to analyze the focus groups. Results We identified two themes. "Advocating gender equality in principle" showed how gender (in)equality was seen as a structural issue not connected to the individual health experiences. "Justifying inequality with individualism" showed how the caregivers focused on personalities and interests as a justification of gender inequalities in work division. The justification of gender inequality resulted in a gendered work division which may be related to health inequalities between women and men. Gender inequalities in work division were primarily understood in terms of personality and interests and not in terms of gender. Conclusion The health experience of the participants was affected by gender (in)equality in terms of a gendered work division. However, the participants did not see the gendered work division as a gender equality issue. Gender perspectives are needed to improve the health of the employees at the workplaces through shifting from individual to structural solutions. A healthy-setting approach considering gender relations is needed to achieve gender equality and fairness in health status between women and men. PMID:22217427
33 CFR 274.6 - Division/district pest control programs.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Division/district pest control..., DEPARTMENT OF DEFENSE PEST CONTROL PROGRAM FOR CIVIL WORKS PROJECTS Project Operation § 274.6 Division/district pest control programs. (a) Guides. Referenced technical manuals, and Engineer Circulars issued...
33 CFR 274.6 - Division/district pest control programs.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Division/district pest control..., DEPARTMENT OF DEFENSE PEST CONTROL PROGRAM FOR CIVIL WORKS PROJECTS Project Operation § 274.6 Division/district pest control programs. (a) Guides. Referenced technical manuals, and Engineer Circulars issued...
33 CFR 274.6 - Division/district pest control programs.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Division/district pest control..., DEPARTMENT OF DEFENSE PEST CONTROL PROGRAM FOR CIVIL WORKS PROJECTS Project Operation § 274.6 Division/district pest control programs. (a) Guides. Referenced technical manuals, and Engineer Circulars issued...
33 CFR 274.6 - Division/district pest control programs.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Division/district pest control..., DEPARTMENT OF DEFENSE PEST CONTROL PROGRAM FOR CIVIL WORKS PROJECTS Project Operation § 274.6 Division/district pest control programs. (a) Guides. Referenced technical manuals, and Engineer Circulars issued...
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
1969-01-01
This is the second edition of the Division of Isotopes Development project summaries. It presents a short summary of objectives, results, and future plans for each research or development project sponsored by the Division within each of eight program areas.
Mazerolle, Stephanie M.; Eason, Christianne M.
2016-01-01
Context: Research suggests that women do not pursue leadership positions in athletic training due to a variety of reasons, including family challenges, organizational constraints, and reluctance to hold the position. The literature has been focused on the National Collegiate Athletic Association Division I setting, limiting our full understanding. Objective: To examine factors that help women as they worked toward the position of head athletic trainer. Design: Qualitative study. Setting: Divisions II and III. Patients or Other Participants: Seventy-seven women who were employed as head athletic trainers at the Division II or III level participated in our study. Participants were 38 ± 9 (range = 24−57) years old and had an average of 14 ± 8 (range = 1−33) years of athletic training experience. Data Collection and Analysis: We conducted online interviews. Participants journaled their reflections to a series of open-ended questions pertaining to their experiences as head athletic trainers. Data were analyzed using a general inductive approach. Credibility was secured by peer review and researcher triangulation. Results: Three organizational facilitators emerged from the data, workplace atmosphere, mentors, and past work experiences. These organizational factors were directly tied to aspects within the athletic trainer's employment setting that allowed her to enter the role. One individual-level facilitator was found: personal attributes that were described as helpful for women in transitioning to the role of the head athletic trainer. Participants discussed being leaders and persisting toward their career goals. Conclusions: Women working in Divisions II and III experience similar facilitators to assuming the role of head athletic trainer as those working in the Division I setting. Divisions II and III were viewed as more favorable for women seeking the role of head athletic trainer, but like those in the role in the Division I setting, women must have leadership skills. PMID:27529359
[Gender plays a role in the young physicians work situation].
Linder, Lisa; Hammarström, Anne
2015-09-22
The purpose of this study was to examine medical interns' experiences of being a female versus a male physician in various work situations. The population consisted of interns within Umeå health care district (n=38). Data was collected using a questionnaire with open-ended questions that were analysed with qualitative content analysis. Our results revealed that the participants experienced different expectations on female and male practitioners from both patients and staff. We also found distinct experiences of discrimination of female practitioners in areas such as patient and staff conduct, service, division of labour and employment. Our conclusion is that there is a need to promote gender equality within the health care system as well as to strengthen research and education regarding gender in medicine.
Gravity and the orientation of cell division
NASA Technical Reports Server (NTRS)
Helmstetter, C. E.
1997-01-01
A novel culture system for mammalian cells was used to investigate division orientations in populations of Chinese hamster ovary cells and the influence of gravity on the positioning of division axes. The cells were tethered to adhesive sites, smaller in diameter than a newborn cell, distributed over a nonadhesive substrate positioned vertically. The cells grew and divided while attached to the sites, and the angles and directions of elongation during anaphase, projected in the vertical plane, were found to be random with respect to gravity. However, consecutive divisions of individual cells were generally along the same axis or at 90 degrees to the previous division, with equal probability. Thus, successive divisions were restricted to orthogonal planes, but the choice of plane appeared to be random, unlike the ordered sequence of cleavage orientations seen during early embryo development.
Criminal Division - Alaska Department of Law
Criminal Division The Criminal Division works to assure safe and healthy communities by prosecuting and live in safe and healthy communities. The day-to-day prosecution services are carried out by the implicated in environmental crimes from further operations that damage the environment. The ECU is partially
Proceedings of the Twenty-Eighth General Assembly Beijing 2012
NASA Astrophysics Data System (ADS)
Montmerle, Thierry
2015-09-01
Preface; 1. Inaugural ceremony; 2. Twenty-eighth General Assembly business sessions; 3. Closing ceremony; 4. Resolutions; 5. Report of Executive Committee, 2009-2012; 6. Reports on Division, Commission, and Working Group meetings; 7. Statutes, bye-laws, and working rules; 8. New members admitted at the General Assembly; 9. Divisions and their Commissions.
33 CFR 274.6 - Division/district pest control programs.
Code of Federal Regulations, 2010 CFR
2010-07-01
..., DEPARTMENT OF DEFENSE PEST CONTROL PROGRAM FOR CIVIL WORKS PROJECTS Project Operation § 274.6 Division... from time to time, will be used as guides in selecting the type of chemicals and the method of application in the control of vegetation and pests at civil works projects. (b) Responsibilities and reports...
33 CFR 211.7 - Rights which may be granted by Division and District Engineers.
Code of Federal Regulations, 2010 CFR
2010-07-01
... WITH CIVIL WORKS PROJECTS Temporary Use by Others of Civil Works Real Estate § 211.7 Rights which may.... Division Engineers, the President of the Mississippi River Commission, and District Engineers of districts... of the Mississippi River Commission in granting leases and District Engineers will administer the...
Origins of the Sexual Division of Labor.
ERIC Educational Resources Information Center
Leibowitz, Lila
An interactive, biosocial model of early hominids presents evidence that physical sex differences are not the basis for the sexual division of labor as is commonly believed. Production (the deliberate collection and distribution of food) developed among early hominids as a prerequisite for survival. Although the population appears to have had…
ERIC Educational Resources Information Center
Dean, Kathleen Lis; Rombalski, Patrick; O'Dell, Kyle
2009-01-01
John Carroll University (JCU) is a Jesuit Catholic institution located in University Heights, approximately 10 miles east of Cleveland, Ohio. Founded in 1888, the university has a population of 3,400 undergraduates and 800 graduate students. The Division of Student Affairs at JCU comprises 11 units. The mission of the division is the same as that…
Register-Recall Systems: Tools for Chronic Disease Management in General Practice.
Georgiou, Andrew; Burns, Joan; Penn, Danielle; Infante, Fernando; Harris, Mark
2004-09-01
The Divisions Diabetes and Cardiovascular Disease Quality Improvement Project (DDCQIP) is a national project that aims to promote quality improvement initiatives among Divisions of General Practice. DDCQIP has investigated the growth of Division-based diabetes and cardiovascular disease register-recall systems and the role they play in promoting evidence-based structured care within general practice. In the period 2000-2002, an increase in the number of GPs using register-recall systems and the rise in the number of active registered patients have made it possible to monitor quality of care and health outcome indicators, and contributed to the growth of a Division-based population health program.
Directory of AFRL/HEA Technical Publications Submitted to DTIC from 1969 to 2007
2007-09-01
Research Division ( AFRL /HEA) 2004 to 30 September 1007 – Air Force Research Laboratory , Warfighter Readiness Research Division ( AFRL /HEA...NUMBER 2003 AIR FORCE RESEARCH LABORATORY WARFIGHTER TRAINING RESEARCH DIVISION ( AFRL /HEA) TECHNICAL DOCUMENTS AUTHOR(S) AFRL -HE-AZ-TP-2003...NUMBER WORK UNIT NUMBER 2002 AIR FORCE RESEARCH
Older Caregiving Parents: Division of Household Labor, Marital Satisfaction, and Caregiver Burden
ERIC Educational Resources Information Center
Essex, Elizabeth Lehr; Hong, Jinkuk
2005-01-01
Based on a sample of 126 families, this study investigated how division of household labor is related to marital satisfaction and caregiving burden among older married parents caring for adult children with intellectual disabilities. For mothers, greater spousal participation in household work and satisfaction with the division of labor were…
The Division of Labor in Lesbian, Gay, and Heterosexual New Adoptive Parents
ERIC Educational Resources Information Center
Goldberg, Abbie E.; Smith, JuliAnna Z.; Perry-Jenkins, Maureen
2012-01-01
Little research has investigated the division of child care and housework in adoptive or lesbian/gay parent families, yet these contexts "control for" family characteristics such as biological relatedness and parental gender differences known to be linked to family work. This study examined predictors (measured preadoption) of the division of…
Joint Service Aircrew Mask (JSAM) - Strategic Aircraft (SA): Noise Attenuation Performance
2015-08-25
Billy Swayne Ball Aerospace and Technologies Corp. Dayton, OH Hilary Gallagher Warfighter Interface Division Battlespace Acoustics Branch...DISTRIBUTION STATEMENT. //signed// //signed// Hilary Gallagher Robert C. McKinley Work Unit Manager Chief, Battlespace Acoustics Branch...Battlespace Acoustics Branch Warfighter Interface Division //signed// William E. Russell, Chief Warfighter Interface Division Human
ERIC Educational Resources Information Center
Templeton, Mary Anne
2007-01-01
The Alabama Division of the American Rehabilitation Association is an organization committed to representing those counselors who work in the field of rehabilitation across the state. The division is focused on offering leadership within the field of rehabilitation counseling, promoting professional development opportunities for counselors, and…
Social Relationships and Health Behavior Across Life Course
Umberson, Debra; Crosnoe, Robert; Reczek, Corinne
2011-01-01
Sociological theory and research point to the importance of social relationships in affecting health behavior. This work tends to focus on specific stages of the life course, with a division between research on childhood/adolescent and adult populations. Yet recent advances demonstrate that early life course experiences shape health outcomes well into adulthood. We synthesize disparate bodies of research on social ties and health behavior throughout the life course, with attention to explaining how various social ties influence health behaviors at different life stages and how these processes accumulate and reverberate throughout the life course. PMID:21921974
Epidemiology & Genomics Research Program
The Epidemiology and Genomics Research Program, in the National Cancer Institute's Division of Cancer Control and Population Sciences, funds research in human populations to understand the determinants of cancer occurrence and outcomes.
Monoclonal antibodies for the separate detection of halodeoxyuridines and method for their use
Vanderlaan, M.; Watkins, B.E.; Stanker, L.H.
1991-10-01
Monoclonal antibodies are described which have specific affinities for halogenated nucleoside analogs and are preferentially selective for one particular halogen. Such antibodies, when incorporated into immunochemical reagents, may be used to identify and independently quantify the cell division character of more than one population or subpopulation in flow cytometric measurements. Independent assessment of division activity in cell sub-populations facilitates selection of appropriate time and dose for administration of anti-proliferative agents. The hybridomas which secrete halogen selective antibodies and the method of making them are described. 14 figures.
Monoclonal antibodies for the separate detection of halodeoxyuridines and method for their use
Vanderlaan, Martin; Watkins, Bruce E.; Stanker, Larry H.
1991-01-01
Monoclonal antibodies are described which have specific affinities for halogenated nucleoside analogs and are preferentially selective for one particular halogen. Such antibodies, when incorporated into immunochemical reagents, may be used to identify and independently quantify the cell division character of more than one population or subpopulation in flow cytometric measurements. Independent assessment of division activity in cell sub-populations facilitates selection of appropriate time and dose for administration of anti-proliferative agents. The hybridomas which secrete halogen selective antibodies and the method of making them are described.
Replacement Migration: Is It a Solution to Declining and Ageing Populations?
ERIC Educational Resources Information Center
United Nations, New York, NY. Dept. of Economic and Social Affairs.
The United Nations (UN) Population Division monitors fertility, mortality, and migration trends for all countries as a basis for producing the official UN population estimates and projections. Among recent demographic trends, two are prominent: (1) population decline and (2) population aging. Focusing on these two critical trends, a study…
ERIC Educational Resources Information Center
Seccombe, Karen
1986-01-01
Tested Kohn's theory that people who work in highly supervised, routinized occupations are likely to value obedience and conformity in marital and parental relationships. Findings from 244 couples revealed that working conditions were not strong predictors of division of household labor. Concludes that nontraditional gender role values,…
What Contributes to the (Im)Balanced Division of Family Work Between the Sexes?
Lothaller, Harald; Mikula, Gerold; Schoebi, Dominik
2011-01-01
This study examines a comprehensive set of variables that have been proposed as explaining the imbalance of the division of family work between the sexes. The analyses use survey data of 735 dual-earner couples from Austria, the Netherlands, and Portugal. The results support theoretical explanations referring to time availability, gender ideology, relative resources, and the importance of characteristics of the family system. No support was obtained for the doing-gender perspective. Additional findings suggest that increased consideration of psychological concepts adds to the understanding of why women do more family work than men. The analyses revealed similarities, but also differences between the factors that contribute to the division of household labor and childcare. PMID:22318972
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
This eighth annual report of the Division covers work done during FY 1981 (October 1, 1980, through September 30, 1981). As with these documents in the past, the format follows approximately the organizational structure of the Energy Division. Chapters 2 through 6 summarize the activities of the sections of the Division: Environmental Impact Section, headed by H.E. Zittel; Regional and Urban Studies Section, R.M. Davis; Economic Analysis Section, R.B. Shelton; Data and Analysis Section, A.S. Loebl; and Efficiency and Renewables Research Section, J.W. Michel. In addition, work on a variety of projects which cut across section lines is reported inmore » Chapter 7, Integrated Programs. These activities are under the supervision of T.J. Wilbanks, Associate Director for the Division. Separate abstracts are included for individual projects.« less
Environmental Sciences Division annual progress report for period ending September 30, 1991
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1992-04-01
This progress report summarizes the research and development activities conducted in the Environmental Sciences Division of Oak Ridge National Laboratory during the period October 1, 1990, through September 30, 1991. The report is structured to provide descriptions of current activities and accomplishments in each of the division`s major organizational units. Following the sections describing the organizational units is a section devoted to lists of information necessary to convey the scope of the work in the division. The Environmental Sciences Division (ESD) at Oak Ridge National Laboratory (ORNL) conducts environmental research and analyses associated with both energy technology development and themore » interactions between people and the environment. The division engages in basic and applied research for a diverse list of sponsors. While the US Department of Energy (DOE) is the primary sponsor ESD staff also perform research for other federal agencies, state agencies, and private industry. The division works collaboratively with federal agencies, universities, and private organizations in achieving its research objectives and hosts a large number of visiting investigators from these organizations. Given the diverse interdisciplinary specialization of its staff, ESD provides technical expertise on complex environmental problems and renders technical leadership for major environmental issues of national and local concern. This progress report highlights many of ESD`s accomplishment in these and other areas in FY 1991.« less
Mazerolle, Stephanie M; Bruening, Jennifer E; Casa, Douglas J
2008-01-01
Context: Work-family conflict (WFC) involves discord that arises when the demands of work interfere with the demands of family or home life. Long work hours, minimal control over work schedules, and time spent away from home are antecedents to WFC. To date, few authors have examined work-family conflict within the athletic training profession. Objective: To investigate the occurrence of WFC in certified athletic trainers (ATs) and to identify roots and factors leading to quality-of-life issues for ATs working in the National Collegiate Athletic Association Division I-A setting. Design: Survey questionnaire and follow-up, in-depth, in-person interviews. Setting: Division I-A universities sponsoring football. Patients or Other Participants: A total of 587 ATs (324 men, 263 women) responded to the questionnaire. Twelve ATs (6 men, 6 women) participated in the qualitative portion: 2 head ATs, 4 assistant ATs, 4 graduate assistant ATs, and 2 AT program directors. Data Collection and Analysis: Multiple regression analysis was performed to determine whether workload and travel predicted levels of WFC. Analyses of variance were calculated to investigate differences among the factors of sex, marital status, and family status. Interviews were transcribed verbatim and then analyzed using computer software as well as member checks and peer debriefing. The triangulation of the data collection and multiple sources of qualitative analysis were utilized to limit potential researcher prejudices. Results: Regression analyses revealed that long work hours and travel directly contributed to WFC. In addition to long hours and travel, inflexible work schedules and staffing patterns were discussed by the interview participants as antecedents to WFC. Regardless of sex (P = .142), marital status (P = .687), family status (P = .055), or age of children (P = .633), WFC affected Division I-A ATs. Conclusions: No matter their marital or family status, ATs employed at the Division I-A level experienced difficulties balancing their work and home lives. Sources of conflict primarily stemmed from the consuming nature of the profession, travel, inflexible work schedules, and lack of full-time staff members. PMID:18833313
Background Information | Division of Cancer Prevention
The Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial is a large population-based randomized trial evaluating screening programs for these cancers. The primary goal of this long-term trial of the National Cancer Institute's (NCI) Division of Cancer Prevention (DCP) is to determine the effects of screening on cancer-related mortality and on secondary
Rodilla, V
1993-08-01
It has recently been described that cisplatin is an agent able to induce binucleated cells (BC) in cultured CHO cells. Both the origin and the significance of those cells within a population are unknown although several hypothesis have been suggested such as blocking of cytokinesis or cell fusion. Using interval photography we have found that at least two mechanisms are involved in the production of BC. These cells can arise in a culture as a result of an incomplete process of cell division, i.e. karyokinesis with incomplete cytokinesis or as a result of the mitotic division of a pre-existent BC. The mitotic division of a BC can give rise to different types of daughter cells. These BC sometimes enter mitosis but fail to divide and as a consequence they remain BC. When the process of division is successful (in the vast majority of cases), the results that have been found are either two mononucleated cells or one mononucleated and one binucleated cell. The possible implications and significance of BC and BC with micronuclei in a given population are discussed.
15 CFR 90.6 - Where to file challenge.
Code of Federal Regulations, 2011 CFR
2011-01-01
... CENSUS, DEPARTMENT OF COMMERCE PROCEDURE FOR CHALLENGING CERTAIN POPULATION AND INCOME ESTIMATES § 90.6... filed with the Chief, Population Division, Bureau of the Census, Room 2011, Federal Building 3...
15 CFR 90.6 - Where to file challenge.
Code of Federal Regulations, 2010 CFR
2010-01-01
... CENSUS, DEPARTMENT OF COMMERCE PROCEDURE FOR CHALLENGING CERTAIN POPULATION AND INCOME ESTIMATES § 90.6... filed with the Chief, Population Division, Bureau of the Census, Room 2011, Federal Building 3...
15 CFR 90.6 - Where to file challenge.
Code of Federal Regulations, 2013 CFR
2013-01-01
... CENSUS, DEPARTMENT OF COMMERCE PROCEDURE FOR CHALLENGING CERTAIN POPULATION AND INCOME ESTIMATES § 90.6... filed with the Chief, Population Division, Bureau of the Census, Room 2011, Federal Building 3...
15 CFR 90.6 - Where to file challenge.
Code of Federal Regulations, 2012 CFR
2012-01-01
... CENSUS, DEPARTMENT OF COMMERCE PROCEDURE FOR CHALLENGING CERTAIN POPULATION AND INCOME ESTIMATES § 90.6... filed with the Chief, Population Division, Bureau of the Census, Room 2011, Federal Building 3...
How Did the Answer Get Bigger?
ERIC Educational Resources Information Center
Johanning, Debra I.; Mamer, James D.
2014-01-01
When students begin work with fraction division in fifth grade or sixth grade, they bring with them experiences from whole-number division. Many students think that a division problem should lead to a quotient that is smaller than the dividend. It is also common for students to believe that the dividend should be larger than the divisor. Many, if…
Performance Assessment of the Invisio V60 Tactical System with the X5 Dual In-Ear Headset
2015-06-30
Gallagher Warfighter Interface Division Battlespace Acoustics Branch Wright-Patterson AFB, OH Melissa A. Theis Oak Ridge Institute for Science...Robert C. McKinley Work Unit Manager Chief, Battlespace Acoustics Branch Battlespace Acoustics Branch Warfighter Interface Division...Warfighter Interface Division Dayton, OH Battlespace Acoustics Branch Wright-Patterson AFB OH 45433 711
Leguay, Jean-Jacques; Guern, Jean
1977-01-01
The utilization of 2,4-dichlorophenoxyacetic acid (2,4-D) molecules by Acer pseudoplatanus cells is governed mainly by a glucosylation process. Evidence that 2,4-D glucoside molecules are biologically inactive is presented. 2,3,5-Triiodobenzoic acid (TIBA), by inhibiting 2,4-D glucosylation, has a sparing effect on 2,4-D molecules; thus TIBA treatments increase growth yield (expressed as the ratio of the maximum number of cells produced to the initial concentration of 2,4-D in the culture medium). Significant amounts of intact 2,4-D molecules remain outside and inside the cells when cell division stops at the onset of the stationary phase. This result and the previous demonstration that, at the onset of the stationary phase, 2,4-D is the specific limiting factor of cell division (Leguay JJ, J Guern 1975 Plant Physiol 56: 356-359) suggest that a threshold concentration of auxin is needed for cell division to proceed. The distribution of 2,4-D molecules between the cells and the culture medium is dependent on the population density at the stationary phase. The extracellular 2,4-D concentration at that time is a linear function of the population density whereas intracellular amounts of 2,4-D and 2,4-D metabolites are constant. By using a modified 2-14C,-5,5-dimethyloxazolidine-2,4-dione technique, it has been shown that the intracellular pH is markedly lowered as the population density at the plateau is increased. This intracellular pH modification is likely to be responsible for a large modification of the ratio between intracellular and extracellular auxin concentrations. The intracellular auxin concentration reaches a constant value (about 3 × 10−7m), independent of population density when cell division stops at the onset of the stationary phase suggesting that it represents the threshold value of the control for cell division. PMID:16660072
2012-01-01
Background This paper reports on results of a newly developed questionnaire for the assessment of effort-reward imbalance (ERI) in unpaid household and family work. Methods: Using a cross-sectional population-based survey of German mothers (n = 3129) the dimensional structure of the theoretical ERI model was validated by means of Confirmatory Factor Analysis (CFA). Analyses of Variance were computed to examine relationships between ERI and social factors and health outcomes. Results CFA revealed good psychometric properties indicating that the subscale 'effort' is based on one latent factor and the subscale 'reward' is composed of four dimensions: 'intrinsic value of family and household work', 'societal esteem', 'recognition from the partner', and 'affection from the child(ren)'. About 19.3% of mothers perceived lack of reciprocity and 23.8% showed high rates of overcommitment in terms of inability to withdraw from household and family obligations. Socially disadvantaged mothers were at higher risk of ERI, in particular with respect to the perception of low societal esteem. Gender inequality in the division of household and family work and work-family conflict accounted most for ERI in household and family work. Analogous to ERI in paid work we could demonstrate that ERI affects self-rated health, somatic complaints, mental health and, to some extent, hypertension. Conclusions The newly developed questionnaire demonstrates satisfied validity and promising results for extending the ERI model to household and family work. PMID:22221851
Advice from working women with retired partners.
Cooley, Eileen L; Adorno, Gail
2016-01-01
in the 21st century, as more women are employed full-time and couples increasingly share egalitarian values, more women continue employment after their partners have voluntarily retired. However, we know very little about the experiences of this growing population of women. We asked working women with retired partners to share their advice for other women who may face this developmental transition. Open-ended responses from 97 women were analyzed to identify pertinent issues and themes. Four primary content areas were identified: time management, division of household labor, financial planning, and communication. Communication between partners was both a topic of concern as well as the solution suggested to resolve conflicts or differences that may arise when women live with a retired partner. It is expected that future changes in the workforce and improvements in the gender balance within relationships will continue to impact experiences for working women with retired partners.
15 CFR 90.8 - Review of challenge.
Code of Federal Regulations, 2011 CFR
2011-01-01
..., DEPARTMENT OF COMMERCE PROCEDURE FOR CHALLENGING CERTAIN POPULATION AND INCOME ESTIMATES § 90.8 Review of challenge. The Chief, Population Division, Bureau of the Census, or the Chief's designee shall review the...
15 CFR 90.8 - Review of challenge.
Code of Federal Regulations, 2012 CFR
2012-01-01
..., DEPARTMENT OF COMMERCE PROCEDURE FOR CHALLENGING CERTAIN POPULATION AND INCOME ESTIMATES § 90.8 Review of challenge. The Chief, Population Division, Bureau of the Census, or the Chief's designee shall review the...
15 CFR 90.8 - Review of challenge.
Code of Federal Regulations, 2013 CFR
2013-01-01
..., DEPARTMENT OF COMMERCE PROCEDURE FOR CHALLENGING CERTAIN POPULATION AND INCOME ESTIMATES § 90.8 Review of challenge. The Chief, Population Division, Bureau of the Census, or the Chief's designee shall review the...
15 CFR 90.8 - Review of challenge.
Code of Federal Regulations, 2010 CFR
2010-01-01
..., DEPARTMENT OF COMMERCE PROCEDURE FOR CHALLENGING CERTAIN POPULATION AND INCOME ESTIMATES § 90.8 Review of challenge. The Chief, Population Division, Bureau of the Census, or the Chief's designee shall review the...
Energy Division annual progress report for period ending September 30, 1983
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
This report covers work done during FY 1983 by the staff of the Energy Division and its subcontractors and by colleagues in other Oak Ridge National Laboratory divisions working on Energy Division projects. The work can be divided into four areas: (1) analysis and assessment, (2) models and data systems, (3) research to improve the efficiency of energy use and to improve electric power transmission and distribution, and (4) research utilization. Support came principally from the US Department of Energy (DOE), the US Nuclear Regulatory Commission, and the US Department of Defense, but also from a number of other agenciesmore » and organizations. Analysis and assessment included work on (a) environmental issues, including those deriving from the preparation of environmental impact statements; (b) energy and resource analysis; and (c) emergency preparedness. The models and data systems area involved research on evaluating and developing energy, environment, and engineering simulation models and on devising large data management systems, evaluating user data requirements, and compiling data bases. Research on improving the efficiency of energy use was focused primarily on the buildings and electricity sectors. A major effort on heat pump technology, which includes both heat-activated and electrically driven systems, continues. An important aspect of all the work was research utilization. Since the Energy Division is doing applied research, results are, by definition, intended to solve problems or answer questions of DOE and other sponsors. However, there are other users, and research utilization activities include technology transfer, commercialization efforts, outreach to state and regional organizations, and, of course, information dissemination.« less
Cancer growth and its inhibition in terms of coherence.
Popp, Fritz-Albert
2009-01-01
It is shown that a molecular origin for growth inhibition is rather unlikely because the cross-sectional area of inhibitory forces in a cell population cannot exceed more than about 10(-8) Dalton. A model of the time dependence of cell number N(t), where t is the time, is based on biophotons and explains without any contradiction to known experimental results growth regulation in terms of the factor a = 1/T, which stimulates the cell division rate dN/dt and the factor b = dT/dN(1/T(2)), which inhibits cell division. It accounts for the total cell division rate dN/dt = aN(t) - bN(2)(t). For adults, T is the coherence time of about 10(6) s, corresponding to the longest lifetime of cell organelles in men, while dT/dN = 10(-7) s corresponds to the resolution time of the cell population which is always the average time interval between two cell loss events. Our model follows a stringently holistic approach to describing a cell population as an entity, regulated by a fully coherent (biophoton) field.
Composite Ceramic Superconducting Wires for Electric Motor Applications
1988-12-30
current a-yi t6-ransition. - Emerson Motor Division has begun work on DC heteropolar and homopolar motor designs. The mechanical stresses on conventional...Emerson Motor Division has begun work on DC heteropolar motor designs and, through Professor Novotny at U. Wisconsin, DC homopolar machines. The...123 3.2 Literature Research .............................. .. 124 3 3.3 Application Study .............................. .. 124 3.3.1 Homopolar Motor
Lawrence A. Oxley and Social Services for Blacks in North Carolina's Appalachian Counties.
ERIC Educational Resources Information Center
Bell, John L.
This paper examines the history of the organization of statewide social services and activities of the Division of Work among Negroes in the Appalachian counties. From 1925-1934--its first 9 years--North Carolina's Division of Work among Negroes was directed by Lawrence Oxley. This agency was established to study black social problems and to help…
15 CFR 90.10 - Form of formal challenge and time limit for filing.
Code of Federal Regulations, 2011 CFR
2011-01-01
... Foreign Trade BUREAU OF THE CENSUS, DEPARTMENT OF COMMERCE PROCEDURE FOR CHALLENGING CERTAIN POPULATION... Chief, Population Division, during the informal stage, and shall include any additional relevant...
15 CFR 90.10 - Form of formal challenge and time limit for filing.
Code of Federal Regulations, 2010 CFR
2010-01-01
... Foreign Trade BUREAU OF THE CENSUS, DEPARTMENT OF COMMERCE PROCEDURE FOR CHALLENGING CERTAIN POPULATION... Chief, Population Division, during the informal stage, and shall include any additional relevant...
15 CFR 90.10 - Form of formal challenge and time limit for filing.
Code of Federal Regulations, 2013 CFR
2013-01-01
... Foreign Trade BUREAU OF THE CENSUS, DEPARTMENT OF COMMERCE PROCEDURE FOR CHALLENGING CERTAIN POPULATION... Chief, Population Division, during the informal stage, and shall include any additional relevant...
15 CFR 90.10 - Form of formal challenge and time limit for filing.
Code of Federal Regulations, 2012 CFR
2012-01-01
... Foreign Trade BUREAU OF THE CENSUS, DEPARTMENT OF COMMERCE PROCEDURE FOR CHALLENGING CERTAIN POPULATION... Chief, Population Division, during the informal stage, and shall include any additional relevant...
Cytokinesis: breaking the ties that bind.
McCollum, Dannel
2005-12-20
It has been unclear how cells complete cell division and resolve membrane connections to bring about cell separation. Recent work has shown that targeted secretion to the midbody is required to complete cell division.
Mazerolle, Stephanie M; Bruening, Jennifer E; Casa, Douglas J; Burton, Laura J
2008-01-01
Context: Previous researchers have shown that work-family conflict (WFC) affects the level of a person's job satisfaction, life satisfaction, and job burnout and intentions to leave the profession. However, WFC and its consequences have not yet been fully investigated among certified athletic trainers. Objective: To investigate the relationship between WFC and various outcome variables among certified athletic trainers working in National Collegiate Athletic Association Division I-A settings. Design: A mixed-methods design using a 53-item survey questionnaire and follow-up in-depth interviews was used to examine the prevalence of WFC. Setting: Division I-A universities sponsoring football. Patients or Other Participants: A total of 587 athletic trainers (324 men, 263 women) responded to the questionnaire, and 12 (6 men, 6 women) participated in the qualitative portion of the mixed-methods study. Data Collection and Analysis: We calculated Pearson correlations to determine the relationship between WFC and job satisfaction, life satisfaction, and job burnout. Regression analyses were run to determine whether WFC was a predictor of job satisfaction, job burnout, or intention to leave the profession. Interviews were transcribed verbatim and then analyzed using the computer program N6 as well as member checks and peer debriefing. Results: Negative relationships were found between WFC and job satisfaction (r = −.52, P < .001). Positive were noted between WFC and job burnout (r = .63, P < .001) and intention to leave the profession (r = .46, P < .001). Regression analyses revealed that WFC directly contributed to job satisfaction (P < .001), job burnout (P < .001), and intention to leave the profession (P < .001). Conclusions: Overall, our findings concur with those of previous researchers on WFC and its negative relationships to job satisfaction and life satisfaction and positive relationship to job burnout and intention to leave an organization. Sources of WFC, such as time, inflexible work schedules, and inadequate staffing, were also related to job burnout and job dissatisfaction in this population. PMID:18833314
The Production of Inequality: The Gender Division of Labor Across the Transition to Parenthood.
Yavorsky, Jill E; Dush, Claire M Kamp; Schoppe-Sullivan, Sarah J
2015-06-01
Using longitudinal time diary and survey data from a community sample of dual-earner couples across the transition to parenthood, the authors examined change in divisions of paid and unpaid work and assessed the accuracy of survey data for time use measurement. Mothers, according to the time diaries, shouldered the majority of child care and did not decrease their paid work hours. Furthermore, the gender gap was not present prebirth but emerged postbirth with women doing more than 2 hours of additional work per day compared to an additional 40 minutes for men. Moreover, the birth of a child magnified parents' overestimations of work in the survey data, and had the authors relied only on survey data, gender work inequalities would not have been apparent. The findings have important implications for (a) the state of the gender revolution among couples well positioned to obtained balanced workloads and (b) the utility of survey data to measure parents' division of labor.
The Production of Inequality: The Gender Division of Labor Across the Transition to Parenthood
Yavorsky, Jill E.; Dush, Claire M. Kamp; Schoppe-Sullivan, Sarah J.
2015-01-01
Using longitudinal time diary and survey data from a community sample of dual-earner couples across the transition to parenthood, the authors examined change in divisions of paid and unpaid work and assessed the accuracy of survey data for time use measurement. Mothers, according to the time diaries, shouldered the majority of child care and did not decrease their paid work hours. Furthermore, the gender gap was not present prebirth but emerged postbirth with women doing more than 2 hours of additional work per day compared to an additional 40 minutes for men. Moreover, the birth of a child magnified parents’ overestimations of work in the survey data, and had the authors relied only on survey data, gender work inequalities would not have been apparent. The findings have important implications for (a) the state of the gender revolution among couples well positioned to obtained balanced workloads and (b) the utility of survey data to measure parents’ division of labor. PMID:26430282
Clarke, Robin; Hackbarth, Andrew S; Saigal, Christopher; Skootsky, Samuel A
2015-10-01
Evolving payer and patient expectations have challenged academic health centers (AHCs) to improve the value of clinical care. Traditional quality approaches may be unable to meet this challenge. One AHC, UCLA Health, has implemented a systematic approach to delivery system redesign that emphasizes clinician engagement, a patient-centric scope, and condition-specific, clinician-guided measurement. A physician champion serves as quality officer (QO) for each clinical department/division. Each QO, with support from a central measurement team, has developed customized analytics that use clinical data to define targeted populations and measure care across the full treatment episode. From October 2012 through June 2015, the approach developed rapidly. Forty-three QOs are actively redesigning care delivery protocols within their specialties, and 95% of the departments/divisions have received a customized measure report for at least one patient population. As an example of how these analytics promote systematic redesign, the authors discuss how Department of Urology physicians have used these new measures, first, to better understand the relationship between clinical practice and outcomes for patients with benign prostatic hyperplasia and, then, to work toward reducing unwarranted variation. Physicians have received these efforts positively. Early outcome data are encouraging. This infrastructure of engaged physicians and targeted measurement is being used to implement systematic care redesign that reliably achieves outcomes that are meaningful to patients and clinicians-incorporating both clinical and cost considerations. QOs are using an approach, for multiple newly launched projects, to identify, test, and implement value-oriented interventions tailored to specific patient populations.
Sex Role Orientation, Wife's Employment, and the Division of Household Labor.
ERIC Educational Resources Information Center
Perlmutter, Jane Clarkson; Wampler, Karen Smith
1985-01-01
This study of 75 families with at least one preschool child examined the effects of sex-role orientation and wife's employment status on the division of housework and child care and husband and wife's satisfaction with that division. Results indicate that where wives work outside the home, husbands and wives share child care and housework more.…
Structures and Acoustics Division
NASA Technical Reports Server (NTRS)
Acquaviva, Cynthia S.
1999-01-01
The Structures and Acoustics Division of NASA Glenn Research Center is an international leader in rotating structures, mechanical components, fatigue and fracture, and structural aeroacoustics. Included are disciplines related to life prediction and reliability, nondestructive evaluation, and mechanical drive systems. Reported are a synopsis of the work and accomplishments reported by the Division during the 1996 calendar year. A bibliography containing 42 citations is provided.
Health and Safety Research Division progress report, October 1, 1988--March 31, 1990
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1990-09-01
The Health and Safety Research Division (HASRD) of the Oak Ridge National Laboratory (ORNL) continues to maintain an outstanding program of basic and applied research displaying a high level of creativity and achievement as documented by awards, publications, professional service, and successful completion of variety of projects. Our focus is on human health and the scientific basis for measurement and assessment of health-related impacts of energy technologies. It is our custom to publish a division progress report every 18 months that summarizes our programmatic progress and other measures of achievement over the reporting period. Since it is not feasible tomore » summarize in detail all of our work over the period covered by this report (October 1, 1988, to March 30, 1990), we intend this document to point the way to the expensive open literature that documents our findings. During the reporting period the Division continued to maintain strong programs in its traditional areas of R D, but also achieved noteworthy progress in other areas. Much of the Division's work on site characterization, development of new field instruments, compilation of data bases, and methodology development fits into this initiative. Other new work in tunneling microscopy in support of DOE's Human Genome Program and the comprehensive R D work related to surface-enhanced Raman spectroscopy have attained new and exciting results. These examples of our progress and numerous other activities are highlighted in this report.« less
Nuclear Technology Division annual progress report for period ending June 30, 1972
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
1972-10-01
This document is a report of progress on technical programs of the Nuclear Technology,Division of Aerojet Nuclear Company for FY 72 ending June 30, 1972. It contains abstracts or expansions of abstracts of papers which have been published within the year. In these cases, preprints or reprints of the articles available. Results of work in progress are also reported; since this work is of a preliminary nature, the authors should be contacted before including any reference to these works in other publications.
Single Mode Optical Waveguide Design Study.
1981-11-23
AD-I7g62 CORNING GLASS WORKS NY FIG 20/6 ADA0 21 SINGLE MODE OPTICAL WAVEGUIDE DESIGN STUDY.(U) NOV 81 V A BHAGAVATJLA. D B KECK, R A WESTWIG N00173...Ralph A. Westwig Corning Glass Works ’ 1 / Research and Development-Division Sullivan Park Corning, New York Th document ha bern c -yro vd Spubc rlea...Authors: Venkata A. Bhagavatula Donald B. Keck Ralph A. Westwig Corning Glass Works Research and Development Division Sullivan Park Corning, New York 11
Navy DD(X), CG(X), and LCS Ship Acquisition Programs: Oversight Issues and Options for Congress
2005-06-24
6. AUTHOR(S) 5d. PROJECT NUMBER 5e . TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Congressional Research...competition between Northrop Grumman’s Ship System Division ( NGSS ) and General Dynamics’ Bath Iron Works (GD/BIW) for the right to build all DD(X)s. The...competition between Northrop Grumman’s Ship System Division ( NGSS ) and General Dynamics’ Bath Iron Works (GD/BIW) for the right to build all DD(X)s
Navy DD(X), GC(X), and LCS Ship Acquisition Programs: Oversight Issues and Options for Congress
2005-08-18
5d. PROJECT NUMBER 5e . TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) David D. Acker Library and Knowledge...System Division ( NGSS ) and General Dynamics’ Bath Iron Works (GD/BIW) for the right to build all DD(X)s. The Emergency Supplemental Appropriations Act...take-all competition between Northrop Grumman’s Ship System Division ( NGSS ) and General Dynamics’ Bath Iron Works (GD/BIW) for the right to build
Specificity and timescales of cortical adaptation as inferences about natural movie statistics.
Snow, Michoel; Coen-Cagli, Ruben; Schwartz, Odelia
2016-10-01
Adaptation is a phenomenological umbrella term under which a variety of temporal contextual effects are grouped. Previous models have shown that some aspects of visual adaptation reflect optimal processing of dynamic visual inputs, suggesting that adaptation should be tuned to the properties of natural visual inputs. However, the link between natural dynamic inputs and adaptation is poorly understood. Here, we extend a previously developed Bayesian modeling framework for spatial contextual effects to the temporal domain. The model learns temporal statistical regularities of natural movies and links these statistics to adaptation in primary visual cortex via divisive normalization, a ubiquitous neural computation. In particular, the model divisively normalizes the present visual input by the past visual inputs only to the degree that these are inferred to be statistically dependent. We show that this flexible form of normalization reproduces classical findings on how brief adaptation affects neuronal selectivity. Furthermore, prior knowledge acquired by the Bayesian model from natural movies can be modified by prolonged exposure to novel visual stimuli. We show that this updating can explain classical results on contrast adaptation. We also simulate the recent finding that adaptation maintains population homeostasis, namely, a balanced level of activity across a population of neurons with different orientation preferences. Consistent with previous disparate observations, our work further clarifies the influence of stimulus-specific and neuronal-specific normalization signals in adaptation.
Specificity and timescales of cortical adaptation as inferences about natural movie statistics
Snow, Michoel; Coen-Cagli, Ruben; Schwartz, Odelia
2016-01-01
Adaptation is a phenomenological umbrella term under which a variety of temporal contextual effects are grouped. Previous models have shown that some aspects of visual adaptation reflect optimal processing of dynamic visual inputs, suggesting that adaptation should be tuned to the properties of natural visual inputs. However, the link between natural dynamic inputs and adaptation is poorly understood. Here, we extend a previously developed Bayesian modeling framework for spatial contextual effects to the temporal domain. The model learns temporal statistical regularities of natural movies and links these statistics to adaptation in primary visual cortex via divisive normalization, a ubiquitous neural computation. In particular, the model divisively normalizes the present visual input by the past visual inputs only to the degree that these are inferred to be statistically dependent. We show that this flexible form of normalization reproduces classical findings on how brief adaptation affects neuronal selectivity. Furthermore, prior knowledge acquired by the Bayesian model from natural movies can be modified by prolonged exposure to novel visual stimuli. We show that this updating can explain classical results on contrast adaptation. We also simulate the recent finding that adaptation maintains population homeostasis, namely, a balanced level of activity across a population of neurons with different orientation preferences. Consistent with previous disparate observations, our work further clarifies the influence of stimulus-specific and neuronal-specific normalization signals in adaptation. PMID:27699416
Gender, division of unpaid family work and psychological distress in dual-earner families.
Tao, Wenting; Janzen, Bonnie L; Abonyi, Sylvia
2010-06-18
Epidemiological studies have only recently begun to address the consequences of unpaid family work (ie., housework and child rearing) for mental health. Although research is suggestive of an association between the division of unpaid family work and psychological health, especially for women, additional research is required to clarify the conditions under which such a relationship holds. The purpose of the present study was to examine more nuanced relationships between the division of family work and psychological distress by disaggregating the family work construct according to type (housework/child rearing), control over scheduling, and evaluations of fairness. Analysis of data obtained from a cross-sectional telephone survey conducted in a Canadian city. Analyses were based on 293 employed parents (182 mothers and 111 fathers), with at least one preschool child, living in dual-earner households. Several multiple linear regression models were estimated with psychological distress as the outcome, adjusting for confounders. For mothers, more perceived time spent in child rearing (particularly primary child care) and high-schedule-control housework tasks (e.g. yard work) relative to one's partner, were associated with greater distress. For fathers, perceived unfairness in the division of housework and child rearing were associated with greater distress. Although methodological limitations temper firm conclusions, these results suggest that the gendered nature of household work has implications for the psychological well-being of both mothers and fathers of preschool children in dual-earner households. However, more longitudinal research and the development of theoretically-informed measures of family work are needed to advance the field.
Metabolism and the Control of Cell Fate Decisions and Stem Cell Renewal
Ito, Kyoko; Ito, Keisuke
2016-01-01
Although the stem cells of various tissues remain in the quiescent state to maintain their undifferentiated state, they also undergo cell divisions as required, and if necessary, even a single stem cell is able to provide for lifelong tissue homeostasis. Stem cell populations are precisely controlled by the balance between their symmetric and asymmetric divisions, with their division patterns determined by whether the daughter cells involved retain their self-renewal capacities. Recent studies have reported that metabolic pathways and the distribution of mitochondria are regulators of the division balance of stem cells and that metabolic defects can shift division balance toward symmetric commitment, which leads to stem cell exhaustion. It has also been observed that in asymmetric division, old mitochondria, which are central metabolic organelles, are segregated to the daughter cell fated to cell differentiation, whereas in symmetric division, young and old mitochondria are equally distributed between both daughter cells. Thus, metabolism and mitochondrial biology play important roles in stem cell fate decisions. As these decisions directly affect tissue homeostasis, understanding their regulatory mechanisms in the context of cellular metabolism is critical. PMID:27482603
Metabolism and the Control of Cell Fate Decisions and Stem Cell Renewal.
Ito, Kyoko; Ito, Keisuke
2016-10-06
Although the stem cells of various tissues remain in the quiescent state to maintain their undifferentiated state, they also undergo cell divisions as required, and if necessary, even a single stem cell is able to provide for lifelong tissue homeostasis. Stem cell populations are precisely controlled by the balance between their symmetric and asymmetric divisions, with their division patterns determined by whether the daughter cells involved retain their self-renewal capacities. Recent studies have reported that metabolic pathways and the distribution of mitochondria are regulators of the division balance of stem cells and that metabolic defects can shift division balance toward symmetric commitment, which leads to stem cell exhaustion. It has also been observed that in asymmetric division, old mitochondria, which are central metabolic organelles, are segregated to the daughter cell fated to cell differentiation, whereas in symmetric division, young and old mitochondria are equally distributed between both daughter cells. Thus, metabolism and mitochondrial biology play important roles in stem cell fate decisions. As these decisions directly affect tissue homeostasis, understanding their regulatory mechanisms in the context of cellular metabolism is critical.
15 CFR 90.9 - When formal procedure may be invoked.
Code of Federal Regulations, 2012 CFR
2012-01-01
... BUREAU OF THE CENSUS, DEPARTMENT OF COMMERCE PROCEDURE FOR CHALLENGING CERTAIN POPULATION AND INCOME ESTIMATES § 90.9 When formal procedure may be invoked. In the event the Chief, Population Division, is...
15 CFR 90.9 - When formal procedure may be invoked.
Code of Federal Regulations, 2010 CFR
2010-01-01
... BUREAU OF THE CENSUS, DEPARTMENT OF COMMERCE PROCEDURE FOR CHALLENGING CERTAIN POPULATION AND INCOME ESTIMATES § 90.9 When formal procedure may be invoked. In the event the Chief, Population Division, is...
15 CFR 90.9 - When formal procedure may be invoked.
Code of Federal Regulations, 2013 CFR
2013-01-01
... BUREAU OF THE CENSUS, DEPARTMENT OF COMMERCE PROCEDURE FOR CHALLENGING CERTAIN POPULATION AND INCOME ESTIMATES § 90.9 When formal procedure may be invoked. In the event the Chief, Population Division, is...
15 CFR 90.9 - When formal procedure may be invoked.
Code of Federal Regulations, 2011 CFR
2011-01-01
... BUREAU OF THE CENSUS, DEPARTMENT OF COMMERCE PROCEDURE FOR CHALLENGING CERTAIN POPULATION AND INCOME ESTIMATES § 90.9 When formal procedure may be invoked. In the event the Chief, Population Division, is...
Our Professional Organizations and the Environmental Dilemma
ERIC Educational Resources Information Center
Granholm, Nels H.
1972-01-01
Summarizes the response by members of the Division of Invertebrate Zoologists of the American Society of Zoologists to a question determining their feelings toward involving the division in work toward resolving pressing ecological problems. (AL)
Work of the Bureau of Education for the Natives of Alaska. Bulletin, 1925, No. 16
ERIC Educational Resources Information Center
Hamilton, William
1925-01-01
This bulletin documents the work of the Alaska division of the Bureau of Education. It reports advance sheets for the biennial survey of education, 1922-1924. The Alaska division is required to make provision for the education of the natives of Alaska, extend to them all possible medical relief, train them to self-support, and, so far as possible,…
Division of labour in the yeast: Saccharomyces cerevisiae.
Wloch-Salamon, Dominika M; Fisher, Roberta M; Regenberg, Birgitte
2017-10-01
Division of labour between different specialized cell types is a central part of how we describe complexity in multicellular organisms. However, it is increasingly being recognized that division of labour also plays an important role in the lives of predominantly unicellular organisms. Saccharomyces cerevisiae displays several phenotypes that could be considered a division of labour, including quiescence, apoptosis and biofilm formation, but they have not been explicitly treated as such. We discuss each of these examples, using a definition of division of labour that involves phenotypic variation between cells within a population, cooperation between cells performing different tasks and maximization of the inclusive fitness of all cells involved. We then propose future research directions and possible experimental tests using S. cerevisiae as a model organism for understanding the genetic mechanisms and selective pressures that can lead to the evolution of the very first stages of a division of labour. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.
Redescription of Strombidium oculatum Gruber 1884 (Ciliophora, Oligotrichia).
Montagnes, David J S; Lowe, Chris D; Poultonb, Alex; Jonsson, Per R
2002-01-01
The marine, tide pool-dwelling ciliate Stombidium oculatum was redescribed using live, stained, SEM, and TEM material prepared from samples collected from pools on the Isle of Man (Irish Sea) and Brittany (France). Also, we reviewed the older German and French works that reported on ciliates collected in the Mediterranean and Brittany, respectively. The Brittany and Isle of Man populations of the ciliate were considered identical. Some morphological and behavioural differences exist between the Brittany-Isle of Man populations and the Mediterranean populations, but they were insufficient to distinguish different taxa. Thus, taxa from all three locations were considered to be conspecific. Key features used to describe the ciliate were: morphology and ultrastructure of the free-swimming ciliate; cyst morphology; presence of mixotrophic-chloroplasts; presence of an eye spot composed of stigma obtained from chlorophyte prey; division, morphogenesis, and nuclear structure; live observations and behaviour, including the encystment-excystment cycle. Based on morphological and behavioural characteristics the taxon was distinguished from other similar species, and a neotype has been designated as no type material exists.
Ahmed, K S
1979-01-01
In Bangladesh the Population Control and Family Planning Division of the Ministry of Health and Population Control has decided to delegate increased financial and administrative powers to the officers of the family planning program at the district level and below. Currently, about 20,000 family planning workers and officials are at work in rural areas. The government believes that the success of the entire family planning program depends on the performance of workers in rural areas, because that is where about 90% of the population lives. Awareness of the need to improve statistical data in Bangladesh has been increasing, particularly in regard to the development of rural areas. An accurate statistical profile of rural Bangladesh is crucial to the formation, implementation and evaluation of rural development programs. A Seminar on Statistics for Rural Development will be held from June 18-20, 1980. The primary objectives of the Seminar are to make an exhaustive analysis of the current availability of statistics required for rural development programs and to consider methodological and operational improvements toward building up an adequate data base.
Environmental Sciences Division annual progress report for period ending September 30, 1991
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1992-04-01
This progress report summarizes the research and development activities conducted in the Environmental Sciences Division of Oak Ridge National Laboratory during the period October 1, 1990, through September 30, 1991. The report is structured to provide descriptions of current activities and accomplishments in each of the division's major organizational units. Following the sections describing the organizational units is a section devoted to lists of information necessary to convey the scope of the work in the division. The Environmental Sciences Division (ESD) at Oak Ridge National Laboratory (ORNL) conducts environmental research and analyses associated with both energy technology development and themore » interactions between people and the environment. The division engages in basic and applied research for a diverse list of sponsors. While the US Department of Energy (DOE) is the primary sponsor ESD staff also perform research for other federal agencies, state agencies, and private industry. The division works collaboratively with federal agencies, universities, and private organizations in achieving its research objectives and hosts a large number of visiting investigators from these organizations. Given the diverse interdisciplinary specialization of its staff, ESD provides technical expertise on complex environmental problems and renders technical leadership for major environmental issues of national and local concern. This progress report highlights many of ESD's accomplishment in these and other areas in FY 1991.« less
Hathaway, R.M.; McNellis, J.M.
1989-01-01
Investigating the occurrence, quantity, quality, distribution, and movement of the Nation 's water resources is the principal mission of the U.S. Geological Survey 's Water Resources Division. Reports of these investigations are published and available to the public. To accomplish this mission, the Division requires substantial computer technology to process, store, and analyze data from more than 57,000 hydrologic sites. The Division 's computer resources are organized through the Distributed Information System Program Office that manages the nationwide network of computers. The contract that provides the major computer components for the Water Resources Division 's Distributed information System expires in 1991. Five work groups were organized to collect the information needed to procure a new generation of computer systems for the U. S. Geological Survey, Water Resources Division. Each group was assigned a major Division activity and asked to describe its functional requirements of computer systems for the next decade. The work groups and major activities are: (1) hydrologic information; (2) hydrologic applications; (3) geographic information systems; (4) reports and electronic publishing; and (5) administrative. The work groups identified 42 functions and described their functional requirements for 1988, 1992, and 1997. A few new functions such as Decision Support Systems and Executive Information Systems, were identified, but most are the same as performed today. Although the number of functions will remain about the same, steady growth in the size, complexity, and frequency of many functions is predicted for the next decade. No compensating increase in the Division 's staff is anticipated during this period. To handle the increased workload and perform these functions, new approaches will be developed that use advanced computer technology. The advanced technology is required in a unified, tightly coupled system that will support all functions simultaneously. The new approaches and expanded use of computers will require substantial increases in the quantity and sophistication of the Division 's computer resources. The requirements presented in this report will be used to develop technical specifications that describe the computer resources needed during the 1990's. (USGS)
Eason, Christianne M; Mazerolle, Stephanie M; Goodman, Ashley
2014-01-01
One of the greatest catalysts for turnover among female athletic trainers (ATs) is motherhood, especially if employed at the National Collegiate Athletic Association Division I level. The medical education literature regularly identifies the importance of role models in professional character formation. However, few researchers have examined the responsibility of mentorship and professional role models as it relates to female ATs' perceptions of motherhood and retention. To evaluate perceptions of motherhood and retention in relation to mentorship and role models among female ATs currently employed in the collegiate setting. Qualitative study. Female athletic trainers working in National Collegiate Athletic Association Division I. Twenty-seven female ATs employed in the National Collegiate Athletic Association Division I setting volunteered. Average age of the participants was 35 ± 9 years. All were full-time ATs with an average of 11 ± 8 years of clinical experience. Participants responded to questions by journaling their thoughts and experiences. Multiple-analyst triangulation and peer review were included as steps to establish data credibility. Male and female role models and mentors can positively or negatively influence the career and work-life balance perceptions of female ATs working in the Division I setting. Female ATs have a desire to see more women in the profession handle the demands of motherhood and the demands of their clinical setting. Women who have had female mentors are more positive about the prospect of balancing the rigors of motherhood and job demands. Role models and mentors are valuable resources for promoting perseverance in the profession in the highly demanding clinical settings. As more female ATs remain in the profession who are able to maintain work-life balance and are available to serve as role models, the attitudes of other women may start to change.
Operator Station Design System - A computer aided design approach to work station layout
NASA Technical Reports Server (NTRS)
Lewis, J. L.
1979-01-01
The Operator Station Design System is resident in NASA's Johnson Space Center Spacecraft Design Division Performance Laboratory. It includes stand-alone minicomputer hardware and Panel Layout Automated Interactive Design and Crew Station Assessment of Reach software. The data base consists of the Shuttle Transportation System Orbiter Crew Compartment (in part), the Orbiter payload bay and remote manipulator (in part), and various anthropometric populations. The system is utilized to provide panel layouts, assess reach and vision, determine interference and fit problems early in the design phase, study design applications as a function of anthropometric and mission requirements, and to accomplish conceptual design to support advanced study efforts.
Total quality management: Strengths and barriers to implementation and cultural adaptation
NASA Technical Reports Server (NTRS)
Siegfeldt, Denise V.; Glenn, Michael; Hamilton, Louise
1992-01-01
NASA/Langley Research Center (LaRC) is in the process of implementing Total Quality Management (TQM) throughout the organization in order to improve productivity and make the Center an even better place to work. The purpose of this project was to determine strengths and barriers to TQM being implemented and becoming a part of the organizational culture of the Human Resources Management Division (HRMD) at Langley. The target population for this project was both supervisory and nonsupervisory staff of the HMRD. In order to generate data on strengths and barriers to TQM implementation and cultural adaptation, a modified nominal group technique was used.
Kinart, Chad M; Cuppett, Marchell M; Berg, Kris
2002-01-01
The purpose of this study was to describe the overall prevalence of migraines within National Collegiate Athletic Association Division I men's and women's basketball players. In addition, the prevalence of migraines was determined across gender and ethnic groups for the same sample. Although numerous studies have assessed the prevalence of migraines within the general population, college students, professional groups, industrial/work place settings, and overseas populations, little has been done with athletes. To the best of our knowledge, no study of the incidence of migraines in athletes has been previously conducted. It has also been reported that migraines cause depression, insomnia, fatigue, anorexia, nausea, and vomiting, all of which might hinder athletic performance. Sports medicine clinicians and researchers also agree that migraines in athletes are probably underreported and often misdiagnosed. Seven hundred ninety-one Division I men and women basketball players representing 51 colleges and universities were mailed a previously validated survey asking questions about headaches. All surveys were analyzed with a validated diagnostic algorithm consistent with the International Headaches Society's (IHS) criteria for headache diagnosis. Descriptive statistics were used to report the prevalence rate for gender and ethnic groups, as well as the entire sample. Chi-square tests were performed (P = 0.05) to determine if there were any differences in the prevalence of migraines among gender and ethnic groups. Results showed that 2.9% (n = 23 of 791) of the total sample was classified as having migraines meeting IHS guidelines. In addition, 0.9% (n = 3 of 332) of men and 4.4% (n = 20 of 459) of women were classified as having migraines meeting IHS guidelines. Additionally, results showed that women reported migraines (chi2 = 8.140, P = 0.004) more often than men. When comparing the prevalence rates of migraines between ethnic groups, results showed that Caucasians had a rate of 3.3% (n = 14 of 429), whereas African Americans had a rate of 3.1% (n = 9 of 287). There was no significant difference found between ethnic groups in migraine prevalence (chi2 = 2.491, P = 0.2888). In conclusion, it was found that the prevalence of migraines in National Collegiate Athletic Association Division I men's and women's basketball players was generally less than in the general population, that women showed an increased prevalence of migraines when compared with men, and that Caucasians and African Americans did not differ in prevalence of migraines.
Mazerolle, Stephanie M; Pitney, William A; Casa, Douglas J; Pagnotta, Kelly D
2011-01-01
Certified athletic trainers (ATs) working at the National Collegiate Athletic Association Division I level experience challenges balancing their professional and personal lives. However, an understanding of the strategies ATs use to promote a balance between their professional and personal lives is lacking. To identify the strategies ATs employed in the Division I setting use to establish a balance between their professional and personal lives. Qualitative investigation using inductive content analysis. Athletic trainers employed at Division I schools from 5 National Athletic Trainers' Association districts. A total of 28 (15 women, 13 men) ATs aged 35 ± 9 years volunteered for the study. Asynchronous electronic interviews with follow-up phone interviews. Data were analyzed using inductive content analysis. Peer review, member checking, and data-source triangulation were conducted to establish trustworthiness. Three higher-order themes emerged from the analysis. The initial theme, antecedents of work-family conflict, focused on the demands of the profession, flexibility of work schedules, and staffing patterns as contributing to work-life conflict for this group of ATs. The other 2 emergent higher-order themes, professional factors and personal factors, describe the components of a balanced lifestyle. The second-order theme of constructing the professional factors included both organizational policies and individual strategies, whereas the second-order theme of personal factors was separation of work and life and a supportive personal network. Long work hours, lack of control over work schedules, and unbalanced athlete-to-AT ratios can facilitate conflicts. However, as demonstrated by our results, several organizational and personal strategies can be helpful in creating a balanced lifestyle.
15 CFR 90.7 - Where to file a challenge.
Code of Federal Regulations, 2014 CFR
2014-01-01
... CENSUS, DEPARTMENT OF COMMERCE PROCEDURE FOR CHALLENGING POPULATION ESTIMATES § 90.7 Where to file a challenge. A request for a population estimate challenge must be prepared in writing by the governmental unit and filed with the Chief, Population Division, Census Bureau, Room 5H174, Mail Stop 8800...
Implications of behavioral architecture for the evolution of self-organized division of labor.
Duarte, A; Scholtens, E; Weissing, F J
2012-01-01
Division of labor has been studied separately from a proximate self-organization and an ultimate evolutionary perspective. We aim to bring together these two perspectives. So far this has been done by choosing a behavioral mechanism a priori and considering the evolution of the properties of this mechanism. Here we use artificial neural networks to allow for a more open architecture. We study whether emergent division of labor can evolve in two different network architectures; a simple feedforward network, and a more complex network that includes the possibility of self-feedback from previous experiences. We focus on two aspects of division of labor; worker specialization and the ratio of work performed for each task. Colony fitness is maximized by both reducing idleness and achieving a predefined optimal work ratio. Our results indicate that architectural constraints play an important role for the outcome of evolution. With the simplest network, only genetically determined specialization is possible. This imposes several limitations on worker specialization. Moreover, in order to minimize idleness, networks evolve a biased work ratio, even when an unbiased work ratio would be optimal. By adding self-feedback to the network we increase the network's flexibility and worker specialization evolves under a wider parameter range. Optimal work ratios are more easily achieved with the self-feedback network, but still provide a challenge when combined with worker specialization.
Implications of Behavioral Architecture for the Evolution of Self-Organized Division of Labor
Duarte, A.; Scholtens, E.; Weissing, F. J.
2012-01-01
Division of labor has been studied separately from a proximate self-organization and an ultimate evolutionary perspective. We aim to bring together these two perspectives. So far this has been done by choosing a behavioral mechanism a priori and considering the evolution of the properties of this mechanism. Here we use artificial neural networks to allow for a more open architecture. We study whether emergent division of labor can evolve in two different network architectures; a simple feedforward network, and a more complex network that includes the possibility of self-feedback from previous experiences. We focus on two aspects of division of labor; worker specialization and the ratio of work performed for each task. Colony fitness is maximized by both reducing idleness and achieving a predefined optimal work ratio. Our results indicate that architectural constraints play an important role for the outcome of evolution. With the simplest network, only genetically determined specialization is possible. This imposes several limitations on worker specialization. Moreover, in order to minimize idleness, networks evolve a biased work ratio, even when an unbiased work ratio would be optimal. By adding self-feedback to the network we increase the network's flexibility and worker specialization evolves under a wider parameter range. Optimal work ratios are more easily achieved with the self-feedback network, but still provide a challenge when combined with worker specialization. PMID:22457609
Family division in China’s transitional economy
Chen, Feinian
2009-01-01
Using a longitudinal data-set (the China Health and Nutrition Survey) we explored the effect of various economic factors, including household wealth, employment sector, and involvement in a household business on the division of extended families in China’s transitional economy. Results from event history analyses suggest that these economic factors act as either a dividing or a unifying force on the extended family. Household wealth reduces the risk of family division, but the effect is weaker for families in which parents have upper secondary education. In addition, an extended family is more likely to divide when married children work in the state sector. Further, the probability of family division is higher in families where daughters-in-law work in the state sector than in those with sons in this sector. Finally, involvement in a household business for married children increases family stability. PMID:19184721
Publications - PIR 2015-5-3 | Alaska Division of Geological & Geophysical
content DGGS PIR 2015-5-3 Publication Details Title: Preliminary investigation of fracture populations in , Preliminary investigation of fracture populations in Mesozoic strata of the Cook Inlet forearc basin: Iniskin
A model with competition between the cell lines in leukemia under treatment
DOE Office of Scientific and Technical Information (OSTI.GOV)
Halanay, A.; Cândea, D.; Rădulescu, R.
2014-12-10
The evolution of leukemia is modeled with a delay differential equation model of four cell populations: two populations (healthy and leukemic) ) of stem-like cells involving a larger category consisting of proliferating stem and progenitor cells with self-renew capacity and two populations (healthy and leukemic) of mature cells, considering the competition of healthy vs. leukemic cell populations and three types of division that a stem-like cell can exhibit: self-renew, asymmetric division and differentiation. In the model it is assumed that the treatment acts on the proliferation rate of the leukemic stem cells and on the apoptosis of stem and maturemore » cells. The emphasis in this model is on establishing relevant parameters for chronic and acute manifestations of leukemia. Stability of equilibria is investigated and sufficient conditions for local asymptotic stability will be given using a Lyapunov-Krasovskii functional.« less
ERIC Educational Resources Information Center
Vranes, Jason
2017-01-01
Higher education institutions have become big businesses that must thrive in the open marketplace to stay viable for the upcoming generation of students. As Generation Z students begin to populate campuses around the country, senior leaders need to possess tools to effectively solicit them. Reaching these online "digital natives" equates…
Coupling Between Metabolism and Compartmentalization: Vesicle Growth in the Presence of Dipeptides
NASA Technical Reports Server (NTRS)
Wei, C.; Pohorille, A.
2017-01-01
A fundamental unresolved question in studies on the origin of life is: how different, ubiquitous protocellular functions begun to work in concert setting the stage for Darwinian evolution of nascent life? From this perspective, of particular significance is coupling between growth of protocellular compartments and the encapsulated, primordial metabolism, which is one of the focal topics of the current ISSOL meeting. Specifically, growth and division of cells facilitated by the products of a metabolic reaction would confer an evolutionary advantage on protocells encapsulating this reaction, as their population would increase at the expense of other protocells. Along these lines, Adamala and Szostak have recently demonstrated that a dipeptide captured inside fatty acid vesicles catalyzes the formation of other dipeptides from activated monomers. Some of the newly synthesized dipeptides, in turn, are capable to promote competitive growth of vesicles in the presence of fatty acid micelles. As vesicles become larger, they adapt filamentous shape, which has been shown to promote their division. On the basis of computer simulations, we provide a molecularly detailed explanation of this process and draw conclusions about its generality.
Riginos, Cynthia
2005-12-01
Comparisons across multiple taxa can often clarify the histories of biogeographic regions. In particular, historic barriers to movement should have affected multiple species and, thus, result in a pattern of concordant intraspecific genetic divisions among species. A striking example of such comparative phylogeography is the recent observation that populations of many small mammals and reptiles living on the Baja California peninsula have a large genetic break between northern and southern peninsular populations. In the present study, I demonstrate that five species of near-shore fishes living on the Baja coastline of the Gulf of California share this genetic pattern. The simplest explanation for this concordant genetic division within both terrestrial and marine vertebrates is that the Baja Peninsula was fragmented by a Plio-Pleistocene marine seaway and that this seaway posed a substantial barrier to movement for near-shore fishes. For some fish species, the signal of this vicariance in mtDNA has been eroded by gene flow and is not evident with classic, equilibrium measures of population structure. Yet, significant divisions are apparent in coalescent analyses that jointly estimate divergence with gene flow. The genetic divisions within Gulf of California fishes also coincide with recognized biogeographic regions based on fish community composition and several environmental factors. It is likely that adaptation to regional environments and present-day oceanographic circulation limit gene exchange between biogeographic regions and help maintain evidence of past vicariance.
ERIC Educational Resources Information Center
Taylor, Lynn; Simpson, Wayne; McClure, Karen; Graham, Barbara; Levin, Benjamin
A Canadian study of the school-to-work transition followed students enrolled in grade 11 in 1990 (n=177), 1992 (n=172), and 1994 (n=347) in Seven Oaks School Division's three high schools. Based largely on questions from the Statistics Canada (SC) School Leavers Survey and SC Graduates Study (1997), the telephone survey focused on these elements:…
Mazerolle, Stephanie M; Eason, Christianne M
2016-07-01
Very few women assume the role of head athletic trainer (AT). Reasons for this disparity include discrimination, motherhood, and a lack of interest in the position. However, data suggest that more women seek the head AT position in National Collegiate Athletic Association Division II and III settings. To examine the barriers female ATs face as they transition to the role of head AT. Qualitative study. Divisions II and III. In total, 77 female ATs participated in our study. Our participants (38 ± 9 years old) were employed as head ATs at the Division II or III level. We conducted online interviews with all participants. They journaled their reflections to a series of open-ended questions pertaining to their experiences as head ATs. Data were analyzed following a general inductive approach. Credibility was secured by peer review and researcher triangulation. Organizational and personal factors emerged as the 2 major themes that described challenges for women assuming the role of the head AT. Organizational barriers were defined by gender stereotyping and the "good old boys" network. Personal influences included a lack of leadership aspirations, motherhood and family, and a lack of mentors. Female ATs working in Divisions II or III experienced similar barriers to assuming the role of the head AT as those working in the Division I setting. Stereotyping still exists within collegiate athletics, which limits the number of women in higher-ranking positions; however, a lack of desire to assume a higher position and the desire to balance work and home inhibit some women from moving up.
Matanoski, G M; Santos-Burgoa, C; Schwartz, L
1990-01-01
A cohort of 12,110 male workers employed 1 or more years in eight styrene-butadiene polymer (SBR) manufacturing plants in the United States and Canada has been followed for mortality over a 40-year period, 1943 to 1982. The all-cause mortality of these workers was low [standardized mortality ratio (SMR) = 0.81] compared to that of the general population. However, some specific sites of cancers had SMRs that exceeded 1.00. These sites were then examined by major work divisions. The sites of interest included leukemia and non-Hodgkin's lymphoma in whites. The SMRs for cancers of the digestive tract were higher than expected, especially esophageal cancer in whites and stomach cancer in blacks. The SMR for arteriosclerotic heart disease in black workers was significantly higher than would be expected based on general population rates. Employees were assigned to a work area based on job longest held. The SMRs for specific diseases differed by work area. Production workers showed increased SMRs for hematologic neoplasms and maintenance workers, for digestive cancers. A significant excess SMR for arteriosclerotic heart disease occurred only in black maintenance workers, although excess mortality from this disease occurred in blacks regardless of where they worked the longest. A significant excess SMR for rheumatic heart disease was associated with work in the combined, all-other work areas. For many causes of death, there were significant deficits in the SMRs. PMID:2401250
Future of Military Health Care Final Report
2007-12-20
Population Health Navigator. Service programs are supported by the Military Health System Population Health Portal (MHSPHP), a centralized, secure...planning is due to Congress on March 1, 2008.66 64 Air Force Medical Support Agency, Population Health Support Division. MHS Population Health Portal ...MTFs are monitoring HEDIS metrics using the MHS Population Health Portal and reporting in the service systems and the Tri- Service Business Planning
Timing the start of division in E. coli: a single-cell study
NASA Astrophysics Data System (ADS)
Reshes, G.; Vanounou, S.; Fishov, I.; Feingold, M.
2008-12-01
We monitor the shape dynamics of individual E. coli cells using time-lapse microscopy together with accurate image analysis. This allows measuring the dynamics of single-cell parameters throughout the cell cycle. In previous work, we have used this approach to characterize the main features of single-cell morphogenesis between successive divisions. Here, we focus on the behavior of the parameters that are related to cell division and study their variation over a population of 30 cells. In particular, we show that the single-cell data for the constriction width dynamics collapse onto a unique curve following appropriate rescaling of the corresponding variables. This suggests the presence of an underlying time scale that determines the rate at which the cell cycle advances in each individual cell. For the case of cell length dynamics a similar rescaling of variables emphasizes the presence of a breakpoint in the growth rate at the time when division starts, τc. We also find that the τc of individual cells is correlated with their generation time, τg, and inversely correlated with the corresponding length at birth, L0. Moreover, the extent of the T-period, τg - τc, is apparently independent of τg. The relations between τc, τg and L0 indicate possible compensation mechanisms that maintain cell length variability at about 10%. Similar behavior was observed for both fast-growing cells in a rich medium (LB) and for slower growth in a minimal medium (M9-glucose). To reveal the molecular mechanisms that lead to the observed organization of the cell cycle, we should further extend our approach to monitor the formation of the divisome.
R and E: Communications and Intelligent Systems Division (LC)
NASA Technical Reports Server (NTRS)
Emerson, Dawn C.; Miranda, Felix A.
2015-01-01
This presentation is intended for the Ohio Federal Research Network's Centers of Excellence. The presentation provides an overview of the Communications and Intelligent Systems Division including current research and engineering work as well as future technology needs.
[Socioenvironmental dilemmas of sustainable development].
Torres, H D
1992-01-01
The literature on sustainable development published in advance of the 1992 United Nations Conference on the Environment and Development, in Rio de Janeiro, focuses on the social politics of the environment and the problems of the correlation of population and the environment. There is an intense preoccupation with the Brazilian environmental agenda and excessive treatment of topics related to the natural environment and the tropical forest of the Amazon. The fact that 75% of the Brazilian population lives in urban areas is ignored. Some works maintain that there is profound division between the conservators of the contemporary predatory and wasteful civilization and those progressive forces that point to the direction of a socially just and ecologically sustainable civilization. Issues that cannot be reduced to environmental questions have come into the forefront in recent years: race, gender, human rights, and pacifism. The question of population growth and pressure on the finite resources have also forcefully featured in debates. The sociology of environment submits that the contemporary civilization cannot be sustained in the medium or long term because of exponential population growth, spatial concentration of the population, depletion of natural resources, systems of production that utilized polluting technologies and low energy efficiency, and values that encourage unlimited material consumption.
ERIC Educational Resources Information Center
Miller, Christina L.
2014-01-01
The purpose of this study is to determine the relationship between physical distance from the headquarters, number of years working within the Division of Agriculture, and job title compared to mission statement and goal focus. The Division of Agriculture as part of the University of Arkansas System is a unique organization because many of its…
JTF CapMed Warrior Transition Division
2011-01-25
The Quadruple Aim: Working Together, Achieving Success 2011 Military Health System Conference JTF CapMed Warrior Transition Division 25 January 2011...Colonel Julia Adams 1 Military Health System Conference Joint Task Force National Capital Region Medical (JTF CapMed ) Report Documentation Page Form...DATES COVERED 00-00-2011 to 00-00-2011 4. TITLE AND SUBTITLE JTF CapMed Warrior Transition Division 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c
Structures and Acoustics Division
NASA Technical Reports Server (NTRS)
Acquaviva, Cynthia S.
2001-01-01
The Structures and Acoustics Division of the NASA Glenn Research Center is an international leader in rotating structures, mechanical components, fatigue and fracture, and structural aeroacoustics. Included in this report are disciplines related to life prediction and reliability, nondestructive evaluation, and mechanical drive systems. Reported is a synopsis of the work and accomplishments completed by the Division during the 1997, 1998, and 1999 calendar years. A bibliography containing 93 citations is provided.
The division of labor: genotypic versus phenotypic specialization.
Wahl, L M
2002-07-01
A model of the division of labor in simple evolving systems is explored to compare two strategies evident in natural populations: phenotypic specialization (such as differentiation by regulated gene expression) and genotypic specialization (such as co-infection by complementary covirus populations). While genotypic specialization is vulnerable to the chance extinction of an essential specialist type and to parasitism, phenotypic specialization is able to overcome these hurdles. When simple spatial effects are included, phenotypic specialization has further benefits, protecting against destructive dynamic patterns. Many of the advantages of phenotypic specialization, however, can only be realized when a high degree of relatedness within groups is ensured.
Clarke, Frank Wigglesworth
1890-01-01
The present bulletin represents work finished in the Division of Chemistry and Physics during the fiscal year 1888—'89, and resembles in general design and purpose its predecessors, Nos. 9, 27, 42, 55, and 60. It covers, however, only a part of the work actually accomplished, for some investigations are not yet completed, others will appear in special bulletins now in course of preparation, and many analyses will be published in forthcoming reports of the field geologists.
ERIC Educational Resources Information Center
Hawaii Univ., Honolulu. East-West Center.
The "information explosion" in the field of population has created a need for proper identification, systematization, dissemination, and utilization of population information. To help meet these needs in the Asian and Pacific regions, the Clearinghouse and Information Section of the Population Division of ESCAP (Economic and Social…
Environment, Safety, and Health Self-Assessment Report, Fiscal Year 2008
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chernowski, John
2009-02-27
Lawrence Berkeley National Laboratory's Environment, Safety, and Health (ES&H) Self-Assessment Program ensures that Integrated Safety Management (ISM) is implemented institutionally and by all divisions. The Self-Assessment Program, managed by the Office of Contract Assurance (OCA), provides for an internal evaluation of all ES&H programs and systems at LBNL. The functions of the program are to ensure that work is conducted safely, and with minimal negative impact to workers, the public, and the environment. The Self-Assessment Program is also the mechanism used to institute continuous improvements to the Laboratory's ES&H programs. The program is described in LBNL/PUB 5344, Environment, Safety, andmore » Health Self-Assessment Program and is composed of four distinct assessments: the Division Self-Assessment, the Management of Environment, Safety, and Health (MESH) review, ES&H Technical Assurance, and the Appendix B Self-Assessment. The Division Self-Assessment uses the five core functions and seven guiding principles of ISM as the basis of evaluation. Metrics are created to measure performance in fulfilling ISM core functions and guiding principles, as well as promoting compliance with applicable regulations. The five core functions of ISM are as follows: (1) Define the Scope of Work; (2) Identify and Analyze Hazards; (3) Control the Hazards; (4) Perform the Work; and (5) Feedback and Improvement. The seven guiding principles of ISM are as follows: (1) Line Management Responsibility for ES&H; (2) Clear Roles and Responsibilities; (3) Competence Commensurate with Responsibilities; (4) Balanced Priorities; (5) Identification of ES&H Standards and Requirements; (6) Hazard Controls Tailored to the Work Performed; and (7) Operations Authorization. Performance indicators are developed by consensus with OCA, representatives from each division, and Environment, Health, and Safety (EH&S) Division program managers. Line management of each division performs the Division Self-Assessment annually. The primary focus of the review is workplace safety. The MESH review is an evaluation of division management of ES&H in its research and operations, focusing on implementation and effectiveness of the division's ISM plan. It is a peer review performed by members of the LBNL Safety Review Committee (SRC), with staff support from OCA. Each division receives a MESH review every two to four years, depending on the results of the previous review. The ES&H Technical Assurance Program (TAP) provides the framework for systematic reviews of ES&H programs and processes. The intent of ES&H Technical Assurance assessments is to provide assurance that ES&H programs and processes comply with their guiding regulations, are effective, and are properly implemented by LBNL divisions. The Appendix B Performance Evaluation and Measurement Plan (PEMP) requires that LBNL sustain and enhance the effectiveness of integrated safety, health, and environmental protection through a strong and well-deployed system. Information required for Appendix B is provided by EH&S Division functional managers. The annual Appendix B report is submitted at the close of the fiscal year. This assessment is the Department of Energy's (DOE) primary mechanism for evaluating LBNL's contract performance in ISM.« less
Population Growth in the 1990s: Patterns within the United States.
ERIC Educational Resources Information Center
Perry, Marc
2002-01-01
Examines population growth during the 1990s for a variety of geographic levels including regions, divisions, states, metropolitan areas, counties, and large cities. Compares growth rates for the 1990s with earlier decades to provide an historical context for present-day trends in population growth and decline. Discusses how differential population…
The poorest first: WHO's activities to help the people in greatest need.
Jancloes, M
1998-01-01
Through its Division of Intensified Cooperation with Countries and Peoples in Greatest Need, WHO is giving special attention to the relationship between poverty and ill-health. The work of the Division is outlined in the present article.
A single-cell pedigree analysis of alternative stochastic lymphocyte fates
Hawkins, E. D.; Markham, J. F.; McGuinness, L. P.; Hodgkin, P. D.
2009-01-01
In contrast to most stimulated lymphocytes, B cells exposed to Toll-like receptor 9 ligands are nonself-adherent, allowing individual cells and families to be followed in vitro for up to 5 days. These B cells undergo phases typical of an adaptive response, dividing up to 6 times before losing the impetus for further growth and division and eventually dying by apoptosis. Using long-term microscopic imaging, accurate histories of individual lymphocyte fates were collected. Quantitative analysis of family relationships revealed that times to divide of siblings were strongly related but these correlations were progressively lost through consecutive divisions. A weaker, but significant, correlation was also found for death times among siblings. Division cessation is characterized by a loss of cell growth and the division in which this occurs is strongly inherited from the original founder cell and is related to the size this cell reaches before its first division. Thus, simple division-based dilution of factors synthesized during the first division may control the maximum division reached by stimulated cells. The stochastic distributions of times to divide, times to die, and divisions reached are also measured. Together, these results highlight the internal cellular mechanisms that control immune responses and provide a foundation for the development of new mathematical models that are correct at both single-cell and population levels. PMID:19633185
ERIC Educational Resources Information Center
Muthoni Thuo, Caroline
2011-01-01
This paper examines the levels of household food security and the influence of enterprise diversification on household food security among small-scale sugarcane farmers in Muhoroni division, Nyando District, Kenya. A cross-sectional research design was used in this study. The population consisted of small-scale sugarcane farmers who grow sugarcane…
1983-06-01
PANEL WORKING GROUP 14 on SUITABLE AVERAGING TECHNIQUES IN NON-UNIFORM INTERNAL FLOWS Edited by M.Pianko Office National d’Etudes et de...d’Etudes et de Recherches Aerospatiales Pratt and Whitney Government Products Division Rocketdyne Division of Rockwell International , Inc. Teledyne CAE...actions exerted by individual components on the gas flow must be known. These specific component effects are distributed internally within the
Analytical Chemistry Division annual progress report for period ending December 31, 1988
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
The Analytical Chemistry Division of Oak Ridge National Laboratory (ORNL) is a large and diversified organization. As such, it serves a multitude of functions for a clientele that exists both in and outside of ORNL. These functions fall into the following general categories: (1) Analytical Research, Development, and Implementation. The division maintains a program to conceptualize, investigate, develop, assess, improve, and implement advanced technology for chemical and physicochemical measurements. Emphasis is on problems and needs identified with ORNL and Department of Energy (DOE) programs; however, attention is also given to advancing the analytical sciences themselves. (2) Programmatic Research, Development, andmore » Utilization. The division carries out a wide variety of chemical work that typically involves analytical research and/or development plus the utilization of analytical capabilities to expedite programmatic interests. (3) Technical Support. The division performs chemical and physicochemical analyses of virtually all types. The Analytical Chemistry Division is organized into four major sections, each of which may carry out any of the three types of work mentioned above. Chapters 1 through 4 of this report highlight progress within the four sections during the period January 1 to December 31, 1988. A brief discussion of the division's role in an especially important environmental program is given in Chapter 5. Information about quality assurance, safety, and training programs is presented in Chapter 6, along with a tabulation of analyses rendered. Publications, oral presentations, professional activities, educational programs, and seminars are cited in Chapters 7 and 8.« less
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-05
... Current Population Survey Annual Social and Economic Supplement Content Test AGENCY: U.S. Census Bureau...) and instructions should be directed to Brian O'Hara, Social and Economic Housing Statistics Division... INFORMATION: I. Abstract The Current Population Survey (CPS) Annual Social and Economic [[Page 39679...
Stoops, William W; Sigmon, Stacey C; Evans, Suzette M
2016-08-01
This is an introduction to the special issue "50th Anniversary of APA Division 28: The Past, Present, and Future of Psychopharmacology and Substance Abuse." Taken together, the scholarly contributions included in this special issue serve as a testament to the important work conducted by our colleagues over the past five decades. Division 28 and its members have advanced and disseminated knowledge on the behavioral effects of drugs, informed efforts to prevent and treat substance abuse, and influenced education and policy issues more generally. As past and current leaders of the division, we are excited to celebrate 50 years of Division 28 and look forward to many more successful decades for our division and its members. (PsycINFO Database Record (c) 2016 APA, all rights reserved).
Task Force on the Future of Military Health Care
2007-12-01
Navigator. Service programs are supported by the Military Health System Population Health Portal (MHSPHP), a centralized, secure, web-based population...Congress on March 1, 2008.66 64 Air Force Medical Support Agency, Population Health Support Division. MHS Population Health Portal Methods. July 2007...HEDIS metrics using the MHS Population Health Portal and reporting in the service systems and the Tri- Service Business Planning tool. DoD has several
Great Expectations: The U.S. Army X Corps in Korea, September-November 1950
2014-05-22
nonetheless commenced operations in Korea with a newly formed team that had little experience working together.37 Moreover, the extensive demobilization...Division landed at Inchon close to full strength, the unit lacked experience , training, and cohesion.58 Like the 7th Infantry Division, the 3d Infantry...equipment’s readiness for operations in Korea. Ernest H. Giusti, Mobilization of the Marine Corps Reserve in the Korean Conflict, 17 Marine Division
1991-10-01
of the Chief of Engineers, such work is advisable. The study was requested by the Washington State Department of Transportation, Marine Division... Marine Division (Washington State Ferries) 31 b. National Marine Fisheries Service 31 c. U.S. Fish and Wildlife Service 32 d. U.S. Environmental Protection...accomplished by the local sponsor through a WDOT, Marine Division, 1991-92 biennium budget request for deepening Keystone Harbor. Assuming WDOT
ERIC Educational Resources Information Center
International Federation of Library Associations and Institutions, The Hague (Netherlands).
The 11 reports and papers in this booklet were presented at meetings of 4 sections within the Division of Bibliographic Control: (1) "Report of the Section on Cataloguing--Review of the Work 1990/1991" (Inger Cathrine Spangen, Norway); (2) "Les fichiers d'autorite auteurs: Rapport d'activite 1990-1991 (Author Authority Lists: Report…
Communications and Intelligent Systems Division - Division Overview
NASA Technical Reports Server (NTRS)
Miranda, Felix A.
2017-01-01
This presentation provides an overview of the research and engineering work being performed in the competency fields of advanced communications and intelligent systems with emphasis on advanced technologies, architecture definition,and systems development for application in current and future aeronautics and space communications systems.
Communications and Intelligent Systems Division - Division Overview
NASA Technical Reports Server (NTRS)
Miranda, Felix A.
2017-01-01
This presentation provides an overview of the research and engineering work being performed in the competency fields of advanced communications and intelligent systems with emphasis on advanced technologies, architecture definition, and systems development for application in current and future aeronautics and space communications systems.
Carbon Smackdown: Smart Windows (LBNL Summer Lecture Series)
Milliron, Delia; Selkowitz, Stephen
2017-12-09
August 3, 2010 Berkeley Lab talk: In the fourth of five Carbon Smackdown matches, Berkeley Lab researchers Delia Milliron of the Materials Sciences Division and Stephen Selkowitz of the Environmental Energy Technologies Division talk about their work on energy-saving smart windows.
Environmental Sciences Division annual progress report for period ending September 30, 1994
DOE Office of Scientific and Technical Information (OSTI.GOV)
NONE
1994-12-31
This progress report summarizes the research and development activities conducted in the Environmental Sciences Division (ESD) of Oak Ridge National Laboratory during fiscal year (FY) 1994, which extended from October 1, 1993, through September 30, 1994. The report is structured to provide descriptions of current activities and accomplishments in each of the division`s major organizational units. Following the sections describing the organizational units are sections highlighting ESD Scientific, Technical, and Administrative Achievement awards and listing information necessary to covey the scope of the work in the division. An organizational chart of staff and long-term guests who wee in ESD atmore » the end of FY 1994 is located in the final section of the report.« less
Mazerolle, Stephanie M.; Pitney, William A.; Casa, Douglas J.; Pagnotta, Kelly D.
2011-01-01
Abstract Context: Certified athletic trainers (ATs) working at the National Collegiate Athletic Association Division I level experience challenges balancing their professional and personal lives. However, an understanding of the strategies ATs use to promote a balance between their professional and personal lives is lacking. Objective: To identify the strategies ATs employed in the Division I setting use to establish a balance between their professional and personal lives. Design: Qualitative investigation using inductive content analysis. Setting: Athletic trainers employed at Division I schools from 5 National Athletic Trainers' Association districts. Patients or Other Participants: A total of 28 (15 women, 13 men) ATs aged 35 ± 9 years volunteered for the study. Data Collection and Analysis: Asynchronous electronic interviews with follow-up phone interviews. Data were analyzed using inductive content analysis. Peer review, member checking, and data-source triangulation were conducted to establish trustworthiness. Results: Three higher-order themes emerged from the analysis. The initial theme, antecedents of work–family conflict, focused on the demands of the profession, flexibility of work schedules, and staffing patterns as contributing to work–life conflict for this group of ATs. The other 2 emergent higher-order themes, professional factors and personal factors, describe the components of a balanced lifestyle. The second-order theme of constructing the professional factors included both organizational policies and individual strategies, whereas the second-order theme of personal factors was separation of work and life and a supportive personal network. Conclusions: Long work hours, lack of control over work schedules, and unbalanced athlete-to-AT ratios can facilitate conflicts. However, as demonstrated by our results, several organizational and personal strategies can be helpful in creating a balanced lifestyle. PMID:21391805
Mazerolle, Stephanie M.; Eason, Christianne M.
2016-01-01
Context: Very few women assume the role of head athletic trainer (AT). Reasons for this disparity include discrimination, motherhood, and a lack of interest in the position. However, data suggest that more women seek the head AT position in National Collegiate Athletic Association Division II and III settings. Objective: To examine the barriers female ATs face as they transition to the role of head AT. Design: Qualitative study. Setting: Divisions II and III. Patients or Other Participants: In total, 77 female ATs participated in our study. Our participants (38 ± 9 years old) were employed as head ATs at the Division II or III level. Data Collection and Analysis: We conducted online interviews with all participants. They journaled their reflections to a series of open-ended questions pertaining to their experiences as head ATs. Data were analyzed following a general inductive approach. Credibility was secured by peer review and researcher triangulation. Results: Organizational and personal factors emerged as the 2 major themes that described challenges for women assuming the role of the head AT. Organizational barriers were defined by gender stereotyping and the “good old boys” network. Personal influences included a lack of leadership aspirations, motherhood and family, and a lack of mentors. Conclusions: Female ATs working in Divisions II or III experienced similar barriers to assuming the role of the head AT as those working in the Division I setting. Stereotyping still exists within collegiate athletics, which limits the number of women in higher-ranking positions; however, a lack of desire to assume a higher position and the desire to balance work and home inhibit some women from moving up. PMID:27548879
Instrumentation and Controls Division progress report for the period July 1, 1986 to June 30, 1988
DOE Office of Scientific and Technical Information (OSTI.GOV)
Klobe, L.E.
1988-12-01
The Instrumentation and Controls (IandC) Division of Oak Ridge National Laboratory (ORNL) performs basic and applied instrumentation and controls research, development and design engineering, specialized instrument design and fabrication, and maintenance services for instruments, electronics, and computers. The IandC Division is one of the largest RandD organizations of its type among government laboratories, and it exists as the result of an organizational strategy to integrate ORNL's instrumentation and controls-related disciplines into one dedicated functional organization to increase the Laboratory's expertise and capabilities in these rapidly expanding, innovative areas of technology. The Division participates in the programs and projects of ORNLmore » by applying its expertise and capabilities in concert with other divisions to perform basic research and mission-oriented technology development. Many of the Division's RandD tasks that are a part of a larger ORNL program are of sufficient scope that the IandC effort constitutes a separate program element with direct funding and management responsibility within the Division. The activities of IandC include performance of an RandD task in IandC facilities, the participation of from one of many IandC engineers and scientists in a multidisciplinary team working in a specific research area or development project, design and fabrication of a special instrument or instrumentation system, or a few hours of maintenance service. In its support and maintenance work, the role of the IandC Division is to provide a level of expertise appropriate to complete a job successfully at minimum overall cost and time schedule---a role which involves IandC in almost all ORNL activities.« less
[Efficiency assessment of investment in workers' health--economic issues].
Rydlewska-Liszkowska, Izabela; Dawydzik, Lech T
2002-01-01
The economic analysis of efficiency of investment in health care and health at large by means of cost-benefit or cost-effectiveness techniques is the subject of implementation work in a number of countries. Poland's integration with the countries of the European Union justifies the need to understand and to use economic analyses. Unfortunately, these activities encounter many methodological and executive barriers. The investments in workers' health are not only investments in health care and the improvement of working conditions, but also in compensations, including financial ones, resulting from adverse effects of factors influencing the health of working population. The financial reporting system that exists in Poland does not ensure the possibility of full presentation of the aggregated data on the financing of activities for workers' health and diminishing of the adverse effects of factors present in the work environment. The information on the outcome of the investments in workers' health come from different sources, which means that it applies to different groups subjected to the analysis. The problem lies not only in the assessment of profitability of health investments but also in the social problem of the division of the resultant costs and benefits among various branches of the national economy. Therefore, the analyses involving mutual relations between individual sectors that invest in workers' health and those that bear consequences is essential in the terms of economic analyses. The authors present the determinants of economic evaluation in regard to health of working population in Poland.
Berntsson, L; Lundberg, U; Krantz, G
2006-12-01
To analyse gender differences in paid and unpaid workload and symptoms in matched groups of Swedish white-collar workers with children. Paid and unpaid workload and perceived stress from paid work, conflict between demands and control over household work were measured by a total workload (TWL) questionnaire. Some symptoms were rated with regard to frequency and severity as a measure of health. Cross-sectional analyses were performed. Matched groups of male (n = 440) and female (n = 529) well-educated white-collar workers in full-time employment, aged 32-58 years and living with children in the home. Women in higher positions in Sweden are healthier than the average population of women, but report more symptoms than men in the same position as well as more stress from paid work, more conflict between demands and a greater TWL. However, women also reported more control over household duties and TWL was not associated with more symptoms. The men were mainly focused on their paid work role and perhaps even more so than men in the general population as they were fairly resistant to feelings of conflicting demands. Even among matched groups of full-time employed, well-educated men and women, traditional gender differences in division of responsibilities and time allocation were found. Even though the women were healthy at this stage, they might risk future ill health, owing to high workload, stress and feelings of conflicting demands.
DOE Office of Scientific and Technical Information (OSTI.GOV)
McDonald, D.W.
This report contains a record of publishing and other activities in the Oak Ridge National Laboratory (ORNL) Instrumentation and Controls (I&C) Division for the period of July 1, 1994, to December31, 1997. It is a companion volume to Working Together on New Horizons: Instrumentation and Controls Division Progress Report for the Period of July 1, 1994, to December 31, 1997 (OR.NLA4-6530). Working Together on New Horizons contains illustrated summaries of some of the projects under way in I&C Division. Both books can be obtained by contacting C. R. Brittain (brittain@ornl. gov), P.O. Box 2008, Oak Ridge, TN 37831-6005. l&C Divisionmore » Mission and Vision I&C Division develops and maintains techniques, instruments, and systems that lead to a better understanding of nature and harnessing of natural phenomena for the benefit of humankind. We have dedicated ourselves to accelerating the advancement of science and the transfer of those advancements into products and processes that benefit U.S. industry and enhance the security of our citizens.« less
Thrailkill, K M; Birky, C W
1980-09-01
We report evidence for random drift of mitochondrial allele frequencies in zygote clones of Saccharomyces cerevisiae and Schizosaccharomyces pombe. Monofactorial and bifactorial crosses were done, using strains resistant or sensitive to erythromycin (alleles Er, Es), oligomycin (Or, Os), or diuron (Dr, Ds). The frequencies of resistant and sensitive cells (and thus the frequencies of the resistant and sensitive alleles) were determined for each of a number of clones of diploid cells arising from individual zygotes. Allele frequencies were extremely variable among these zygote clones; some clones were "uniparental," with mitochondrial alleles from only one parent present. These observations suggest random drift of the allele frequencies in the population of mitochondrial genes within an individual zygote and its diploid progeny. Drift would cease when all the cells in a clone become homoplasmic, due to segregation of the mitochondrial genomes during vegetative cell divisions. To test this, we delayed cell division (and hence segregation) for varying times by starving zygotes in order to give drift more time to operate. As predicted, delaying cell division resulted in an increase in the variance of allele frequencies among the zygote clones and an increase in the proportion of uniparental zygote clones. The changes in form of the allele frequency distributions resembled those seen during random drift in finite Mendelian populations. In bifactorial crosses, genotypes as well as individual alleles were fixed or lost in some zygote clones. However, the mean recombination frequency for a large number of clones did not increase when cell division was delayed. Several possible molecular mechanisms for intracellular random drift are discussed.
The Office of the Materials Division
NASA Technical Reports Server (NTRS)
Ramsey, amanda J.
2004-01-01
I was assigned to the Materials Division, which consists of the following branches; the Advanced Metallics Branch/5120-RMM, Ceramics Branch/5130-RMC, Polymers Branch/5150-RMP, and the Durability and Protective Coatings Branch/5160-RMD. Mrs. Pamela Spinosi is my assigned mentor. She was assisted by Ms.Raysa Rodriguez/5100-RM and Mrs.Denise Prestien/5100-RM, who are both employed by InDyne, Inc. My primary assignment this past summer was working directly with Ms. Rodriguez, assisting her with setting up the Integrated Financial Management Program (IFMP) 5130-RMC/Branch procedures and logs. These duties consisted of creating various spreadsheets for each individual branch member, which were updated daily. It was not hard to familiarize myself with these duties since this is my second summer working with Ms Rodriguez at NASA Glenn Research Center. RMC ordering laboratory, supplies and equipment for the Basic Materials Laboratory (Building 106) using the IF'MP/Purchase Card (P-card), a NASA-wide software program. I entered into the IFMP/Travel and Requisitions System, new Travel Authorizations for the 5130-RMC Civil Servant Branch Members. I also entered and completed Travel Vouchers for the 5130-RMC Ceramics Branch. I assisted in the Division Office creating new Emergency Contact list for the Materials Division. I worked with Dr. Hugh Gray, the Division Chief, and Dr. Ajay Misra, the 5130-RMC Branch Chief, on priority action items, with a close deadline, for a large NASA Proposal. Another project was working closely with Ms. Rodriguez in organizing and preparing for Dr. Ajay K. Misra's SESCDP (two year detail). This consisted of organizing files, file folders, personal information, and recording all data material onto CD's and printing all presentations for display in binders. I attended numerous Branch meetings, and observed many changes in the Branch Management organization.
76 FR 76183 - Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-06
... and Kentwood West Plants, Corporate Development Center, Grand Rapids, Michigan. Steelcase, Inc., North America Division, Regional Distribution Center, Grand Rapids, Michigan. Leased Workers From Manpowergroup...., Working On-Site At Steelcase, Inc., North America Division, Kentwood East And Kentwood West Plants...
RESEARCH AND TECHNOLOGY DIVISION REPORT FOR 1966.
ERIC Educational Resources Information Center
BAUM, C.
THE WORK OF THE RESEARCH AND TECHNOLOGY DIVISION OF SYSTEM DEVELOPMENT CORPORATION DURING 1966 IS REPORTED. THE PROGRESS OF VARIOUS STUDIES AND ACTIVITIES DISCUSSED IN THE REPORT WERE ADVANCED PROGRAMING, INFORMATION PROCESSING RESEARCH, PROGRAMING SYSTEMS, DATA BASE SYSTEMS. LANGUAGE PROCESSING AND RETRIEVAL, BEHAVIORAL GAMING AND SIMULATION…
Division C Commission 55: Communicating Astronomy with the Public
NASA Astrophysics Data System (ADS)
Christensen, Lars Lindberg; Russo, Pedro; Fienberg, Richard Tresch; Cheung, Sze-Leung; Robson, Ian; Ödman-Govender, Carolina; Arcand, Kimberly Kowal; Sekiguchi, Kazuhiro; Zhu, Jin; Wheeler, Pete
2016-04-01
The IAU Division C Commission 55, Communicating Astronomy with the Public, played an active role in Union affairs within Division C, Education, Outreach and Heritage. The International Astronomical Union (IAU) vested considerable responsibility for its public outreach efforts in Commission 55 (C55), Communicating Astronomy with the Public. This article briefly recounts the origin and history of C55 over the past decade, and describes the work of C55 until it became Division C Commission C.C2 in 2015. As stated on our website, http://www.communicatingastronomy.org, C55 was founded on the principle that ``it is the responsibility of every practising astronomer to play some role in explaining the interest and value of science to our real employers, the taxpayers of the world.'' While this was true a decade ago, when the Working Group that eventually became C55 first took shape, it is even more true today, when funding for the astronomical sciences (and science more generally) is under threat on nearly every continent.
Many private mutations originate from the first few divisions of a human colorectal adenoma.
Kang, Haeyoun; Salomon, Matthew P; Sottoriva, Andrea; Zhao, Junsong; Toy, Morgan; Press, Michael F; Curtis, Christina; Marjoram, Paul; Siegmund, Kimberly; Shibata, Darryl
2015-11-01
Intratumoural mutational heterogeneity (ITH) or the presence of different private mutations in different parts of the same tumour is commonly observed in human tumours. The mechanisms generating such ITH are uncertain. Here we find that ITH can be remarkably well structured by measuring point mutations, chromosome copy numbers, and DNA passenger methylation from opposite sides and individual glands of a 6 cm human colorectal adenoma. ITH was present between tumour sides and individual glands, but the private mutations were side-specific and subdivided the adenoma into two major subclones. Furthermore, ITH disappeared within individual glands because the glands were clonal populations composed of cells with identical mutant genotypes. Despite mutation clonality, the glands were relatively old, diverse populations when their individual cells were compared for passenger methylation and by FISH. These observations can be organized into an expanding star-like ancestral tree with co-clonal expansion, where many private mutations and multiple related clones arise during the first few divisions. As a consequence, most detectable mutational ITH in the final tumour originates from the first few divisions. Much of the early history of a tumour, especially the first few divisions, may be embedded within the detectable ITH of tumour genomes. Copyright © 2015 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
1983-11-04
Division AREA & WORK UNIT NUMBERS . Department of Chemistry Howard University Washington, D. C. 20059 NR-051-733 1t. CONTROLLING OFFICE NAME AND...Journal of Physical Chemistry Laser Chemistry Division Department of Chemistry Howard University Washington, D. C. 20059 November 4, 1983 *Reproduction in...Victor McCrary, David Zakheim, and William M. Jackson Laser Chemistry Division Chemistry Departmient Howard University Washington, D.C.. 20059 ABSTRACT The
2017-09-14
2014. [24] “United Nations, Department of Economic and Social Affairs, Population Division, World Population Prospects, the 2015 Revision,” http...Research Article Modelling Risk to US Military Populations from Stopping Blanket Mandatory Polio Vaccination Colleen Burgess,1,2 Andrew Burgess,2 and...for polio transmission within military populations interacting with locals in a polio-endemic region to evaluate changes in vaccination policy
Diel Variations in Optical Properties of Micromonas pusilla, a Prasinophyte
NASA Technical Reports Server (NTRS)
DuRand, Michele D.; Green, Rebecca E.; Sosik, Heidi M.; Olson, Robert J.
2001-01-01
A laboratory experiment was conducted on cultures of Micromonas pusilla, a marine prasinophyte, to investigate how cell growth and division affect the optical properties over the light:dark cycle. Measurements were made of cell size and concentration, attenuation and absorption coefficients, flow cytometric light scattering (in forward and side directions), chlorophyll and carbon content. Refractive index was calculated using the anomalous diffraction approximation Cells were about 1.5 micrometers in diameter and exhibited phased division, with the major division burst occurring during the night. Typical diel variations were observed, with cells increasing in size and light scattering during the day as they photosynthesize and decreasing at night upon division. The cells were in ultradian growth, with more than one division per day, at a light level of 120 Mu-mol photons m/sq/sec. Since these cells are similar in size to small phytoplankton that are typically abundant in field samples, these results can be used in the interpretation of diel variations in light scattering in natural populations of phytoplankton.
76 FR 12964 - Agency Forms Undergoing Paperwork Reduction Act Review
Federal Register 2010, 2011, 2012, 2013, 2014
2011-03-09
... standalone survey designed to monitor mental and behavioral health indicators in the adult population in... from other surveys designed to measure anxiety, depression, and potential stress-associated physical.... Proposed Project The Division of Behavior Surveillance (DBS) Gulf States Population Survey--New--Public...
MECHANISMS OF FLUID SHEAR-INDUCED INHIBITION OF POPULATION GROWTH IN A RED-TIDE DINOFLAGELLATE
Net population growth of some dinoflagellates is inhibited by fluid shear at shear stresses comparable with those generated during oceanic turbulence. Decreased net growth may occur through lowered cell division, increased mortality, or both. The dominant mechanism under various ...
Second Annual NASA Ames Space Science and Astrobiology Jamboree
NASA Technical Reports Server (NTRS)
Dotson, Jessie
2014-01-01
The Space Science and Astrobiology Division's researchers are pursuing investigations in a variety of fields, including exoplanets, planetary science, astrobiology, and astrophysics. In addition division personnel support a wide variety of NASA missions. With a wide variety of interesting research going on, distributed among the three branches in at least 5 buildings, it can be difficult to stay abreast of what one's fellow researchers are doing. Our goal in organizing this symposium is to facilitate communication and collaboration among the scientist within the division and to give center management and other ARC researchers and Engineers an opportunity to see what scientific missions work is being done in the division.
Gain control through divisive inhibition prevents abrupt transition to chaos in a neural mass model.
Papasavvas, Christoforos A; Wang, Yujiang; Trevelyan, Andrew J; Kaiser, Marcus
2015-09-01
Experimental results suggest that there are two distinct mechanisms of inhibition in cortical neuronal networks: subtractive and divisive inhibition. They modulate the input-output function of their target neurons either by increasing the input that is needed to reach maximum output or by reducing the gain and the value of maximum output itself, respectively. However, the role of these mechanisms on the dynamics of the network is poorly understood. We introduce a novel population model and numerically investigate the influence of divisive inhibition on network dynamics. Specifically, we focus on the transitions from a state of regular oscillations to a state of chaotic dynamics via period-doubling bifurcations. The model with divisive inhibition exhibits a universal transition rate to chaos (Feigenbaum behavior). In contrast, in an equivalent model without divisive inhibition, transition rates to chaos are not bounded by the universal constant (non-Feigenbaum behavior). This non-Feigenbaum behavior, when only subtractive inhibition is present, is linked to the interaction of bifurcation curves in the parameter space. Indeed, searching the parameter space showed that such interactions are impossible when divisive inhibition is included. Therefore, divisive inhibition prevents non-Feigenbaum behavior and, consequently, any abrupt transition to chaos. The results suggest that the divisive inhibition in neuronal networks could play a crucial role in keeping the states of order and chaos well separated and in preventing the onset of pathological neural dynamics.
Achievements of agrophysics: review of new scientific divisions
USDA-ARS?s Scientific Manuscript database
This work is devoted to review the new scientific divisions that emerged in agrophysics in the last 10-15 years. Among them are the following: 1) application of Geographic Information Systems, 2) development and application of fuzzy multi attributive comparison of alternatives, 3) application of Ad...
Spengler, J J
1970-11-01
Abstract Adam Smith dealt with questions of population mainly in his Wealth of Nations. His discussion falls roughly under five heads and reflects in considerable measure his image of the English economy. (1) A country's population capacity, given the average level of consumption, was conditioned by the stock of land, the skill with which it was cultivated, and the degree to which division of labour could be increased and thereby augment output for domestic use and sale in external markets. (2) Growth of population was essentially in response to growth of the demand for labour and served to increase division of labour. (3) The social mechanisms underlying elevation of the scale of living are touched upon, and in an optimistic spirit. (4) The distribution of a country's population responded to its progress in opulence, with the rate of this progress conditioned by the degree to which inappropriate (e.g. mercantilist) policies were avoided. (5) Smith dealt briefly with such matters as colonies, education, size of economy, environmental influences, and public policy, all of which he recognized as significant for the quantity and quality of a country's numbers.
Genetic variability in captive populations of the stingless bee Tetragonisca angustula.
Santiago, Leandro R; Francisco, Flávio O; Jaffé, Rodolfo; Arias, Maria C
2016-08-01
Low genetic variability has normally been considered a consequence of animal husbandry and a major contributing factor to declining bee populations. Here, we performed a molecular analysis of captive and wild populations of the stingless bee Tetragonisca angustula, one of the most commonly kept species across South America. Microsatellite analyses showed similar genetic variability between wild and captive populations However, captive populations showed lower mitochondrial genetic variability. Male-mediated gene flow, transport and division of nests are suggested as the most probable explanations for the observed patterns of genetic structure. We conclude that increasing the number of colonies kept through nest divisions does not negatively affect nuclear genetic variability, which seems to be maintained by small-scale male dispersal and human-mediated nest transport. However, the transport of nests from distant localities should be practiced with caution given the high genetic differentiation observed between samples from western and eastern areas. The high genetic structure verified is the result of a long-term evolutionary process, and bees from distant localities may represent unique evolutionary lineages.
Rosene, John M; Raksnis, Bryan; Silva, Brie; Woefel, Tyler; Visich, Paul S; Dompier, Thomas P; Kerr, Zachary Y
2017-09-01
Examinations related to divisional differences in the incidence of sports-related concussions (SRC) in collegiate ice hockey are limited. To compare the epidemiologic patterns of concussion in National Collegiate Athletic Association (NCAA) ice hockey by sex and division. Descriptive epidemiology study. A convenience sample of men's and women's ice hockey teams in Divisions I and III provided SRC data via the NCAA Injury Surveillance Program during the 2009-2010 to 2014-2015 academic years. Concussion counts, rates, and distributions were examined by factors including injury activity and position. Injury rate ratios (IRRs) and injury proportion ratios (IPRs) with 95% confidence intervals (CIs) were used to compare concussion rates and distributions, respectively. Overall, 415 concussions were reported for men's and women's ice hockey combined. The highest concussion rate was found in Division I men (0.83 per 1000 athlete-exposures [AEs]), followed by Division III women (0.78/1000 AEs), Division I women (0.65/1000 AEs), and Division III men (0.64/1000 AEs). However, the only significant IRR was that the concussion rate was higher in Division I men than Division III men (IRR = 1.29; 95% CI, 1.02-1.65). The proportion of concussions from checking was higher in men than women (28.5% vs 9.4%; IPR = 3.02; 95% CI, 1.63-5.59); however, this proportion was higher in Division I women than Division III women (18.4% vs 1.8%; IPR = 10.47; 95% CI, 1.37-79.75). The proportion of concussions sustained by goalkeepers was higher in women than men (14.2% vs 2.9%; IPR = 4.86; 95% CI, 2.19-10.77), with findings consistent within each division. Concussion rates did not vary by sex but differed by division among men. Checking-related concussions were less common in women than men overall but more common in Division I women than Division III women. Findings highlight the need to better understand the reasons underlying divisional differences within men's and women's ice hockey and the need to develop concussion prevention strategies specific to each athlete population.
Navy DD(X), CG(X), and LCS Ship Acquisition Programs: Oversight Issues and Options for Congress
2005-04-21
6. AUTHOR(S) 5d. PROJECT NUMBER 5e . TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Congressional Research...between Northrop Grumman’s Ship System Division ( NGSS ) and General Dynamics’ Bath Iron Works (GD/BIW) for the right to build all DD(X)s. Several Members...premature” a Navy proposal to hold a one-time, winner-take-all competition between Northrop Grumman’s Ship System Division ( NGSS ) and General Dynamics
ERIC Educational Resources Information Center
Saunders, Lyle; Harkavy, Oscar
This essay traces the actions taken by governments and private agencies in the past two decades to limit population growth and examines the growing emphasis on linking population and development concerns. It was presented to the annual conference of the Ford Foundation's International Division on September 22, 1975. The time between the end of…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ward, David L.
The authors report on their progress from April 1997 through March 1998 on determining the effects of mitigative measures on productivity of white sturgeon populations in the Columbia River downstream from McNary Dam, and on determining the status and habitat requirements of white sturgeon populations in the Columbia and Snake rivers upstream from McNary Dam. The study is a cooperative effort by the Oregon Department of Fish and Wildlife (ODFW; Report A), Washington Department of Fish and Wildlife (WDFW; Report B), U.S. Geological Survey Biological Resources Division (USGS; Report C), National Marine Fisheries Service (NMFS; Report D), U.S. Fish andmore » Wildlife Service (USFWS; Report E), and Columbia River Inter-Tribal Fish Commission (CRITFC; Report F). This is a multi-year study with many objectives requiring more than one year to complete. Therefore, findings from a given year may be part of more significant findings yet to be reported. Highlights of results of the work from April 1997 through March 1998 listed.« less
1924-07-01
OFFICE. The primary function of the Postal Service is to transfer mail from the sender to the addressee. The major. activities at all post offices in...points. These two divisions are officially designated as the delivery and dispatching divisions, re- spectively. The four other official divisions of...class mail is separated for distribution .outside New York City, it is transported by chute or truck to the pouching department. The work required here
ERIC Educational Resources Information Center
Walker, Marlon A.
2005-01-01
It seems those who have a say in Division I-A athletic personnel matters--athletic directors, booster club leaders--haven't heard the news. There are plenty of qualified Black football and basketball coaches ready to step up and report to work. Out of 117 Division I-A football programs, there are currently three Black head coaches. The number…
The distribution of physiotherapists in ontario: understanding the market drivers.
Holyoke, Paul; Verrier, Molly C; Landry, Michel D; Deber, Raisa B
2012-01-01
To understand the factors that affect the distribution of physiotherapists in Ontario by examining three potential influences in the multi-payer physiotherapy (PT) market: population need, critical mass (related to academic health science centres [AHSCs]), and market forces. Physiotherapist density and distribution were calculated from 2003 and 2005 College of Physiotherapists of Ontario registration data. Physiotherapists' workplaces were classified as not-for-profit (NFP) hospitals, other NFP, or for-profit (FP), and their locations were classified by census division (CD) types (cities and counties). Physiotherapist density varied significantly and distribution was neither uniformly responsive to population need, nor driven primarily by market forces. The largest factor was an AHSC in a CD; physiotherapists locate disproportionately in NFP hospitals in AHSCs rather than in the growing FP sector. While some patterns can be discerned in the distribution and densities of physiotherapists across Ontario, further work needs to be done to identify why population need and market forces appear to be less influential, and why CDs with AHSCs are so attractive to physiotherapists. With this additional information, it may be possible to identify ways to influence uneven distribution in the future.
Population and business exposure to twenty scenario earthquakes in the State of Washington
Wood, Nathan; Ratliff, Jamie
2011-01-01
This report documents the results of an initial analysis of population and business exposure to scenario earthquakes in Washington. This analysis was conducted to support the U.S. Geological Survey (USGS) Pacific Northwest Multi-Hazards Demonstration Project (MHDP) and an ongoing collaboration between the State of Washington Emergency Management Division (WEMD) and the USGS on earthquake hazards and vulnerability topics. This report was developed to help WEMD meet internal planning needs. A subsequent report will provide analysis to the community level. The objective of this project was to use scenario ground-motion hazard maps to estimate population and business exposure to twenty Washington earthquakes. In consultation with the USGS Earthquake Hazards Program and the Washington Division of Geology and Natural Resources, the twenty scenario earthquakes were selected by WEMD (fig. 1). Hazard maps were then produced by the USGS and placed in the USGS ShakeMap archive.
A Bibliometric Analysis on Cancer Population Science with Topic Modeling.
Li, Ding-Cheng; Rastegar-Mojarad, Majid; Okamoto, Janet; Liu, Hongfang; Leichow, Scott
2015-01-01
Bibliometric analysis is a research method used in library and information science to evaluate research performance. It applies quantitative and statistical analyses to describe patterns observed in a set of publications and can help identify previous, current, and future research trends or focus. To better guide our institutional strategic plan in cancer population science, we conducted bibliometric analysis on publications of investigators currently funded by either Division of Cancer Preventions (DCP) or Division of Cancer Control and Population Science (DCCPS) at National Cancer Institute. We applied two topic modeling techniques: author topic modeling (AT) and dynamic topic modeling (DTM). Our initial results show that AT can address reasonably the issues related to investigators' research interests, research topic distributions and popularities. In compensation, DTM can address the evolving trend of each topic by displaying the proportion changes of key words, which is consistent with the changes of MeSH headings.
Skin Stem Cell Hypotheses and Long Term Clone Survival – Explored Using Agent-based Modelling
Li, X.; Upadhyay, A. K.; Bullock, A. J.; Dicolandrea, T.; Xu, J.; Binder, R. L.; Robinson, M. K.; Finlay, D. R.; Mills, K. J.; Bascom, C. C.; Kelling, C. K.; Isfort, R. J.; Haycock, J. W.; MacNeil, S.; Smallwood, R. H.
2013-01-01
Epithelial renewal in skin is achieved by the constant turnover and differentiation of keratinocytes. Three popular hypotheses have been proposed to explain basal keratinocyte regeneration and epidermal homeostasis: 1) asymmetric division (stem-transit amplifying cell); 2) populational asymmetry (progenitor cell with stochastic fate); and 3) populational asymmetry with stem cells. In this study, we investigated lineage dynamics using these hypotheses with a 3D agent-based model of the epidermis. The model simulated the growth and maintenance of the epidermis over three years. The offspring of each proliferative cell was traced. While all lineages were preserved in asymmetric division, the vast majority were lost when assuming populational asymmetry. The third hypothesis provided the most reliable mechanism for self-renewal by preserving genetic heterogeneity in quiescent stem cells, and also inherent mechanisms for skin ageing and the accumulation of genetic mutation. PMID:23712735
Skin stem cell hypotheses and long term clone survival--explored using agent-based modelling.
Li, X; Upadhyay, A K; Bullock, A J; Dicolandrea, T; Xu, J; Binder, R L; Robinson, M K; Finlay, D R; Mills, K J; Bascom, C C; Kelling, C K; Isfort, R J; Haycock, J W; MacNeil, S; Smallwood, R H
2013-01-01
Epithelial renewal in skin is achieved by the constant turnover and differentiation of keratinocytes. Three popular hypotheses have been proposed to explain basal keratinocyte regeneration and epidermal homeostasis: 1) asymmetric division (stem-transit amplifying cell); 2) populational asymmetry (progenitor cell with stochastic fate); and 3) populational asymmetry with stem cells. In this study, we investigated lineage dynamics using these hypotheses with a 3D agent-based model of the epidermis. The model simulated the growth and maintenance of the epidermis over three years. The offspring of each proliferative cell was traced. While all lineages were preserved in asymmetric division, the vast majority were lost when assuming populational asymmetry. The third hypothesis provided the most reliable mechanism for self-renewal by preserving genetic heterogeneity in quiescent stem cells, and also inherent mechanisms for skin ageing and the accumulation of genetic mutation.
Demographic, Educational, Employment, and Professional Characteristics of Counseling Psychologists
ERIC Educational Resources Information Center
Munley, Patrick H.; Pate, William E., II; Duncan, Lonnie E.
2008-01-01
Counseling psychologist members of Division 17 (n = 1,792) were compared with counseling psychologist nonmembers of Division 17 within the American Psychological Association (APA; n = 6,917) with respect to demographic, educational, and professional characteristics reported in the 2003 APA Directory Survey. Employment setting and work activities…
Staff - Patricia E. Gallagher | Alaska Division of Geological & Geophysical
Alaska's Mineral Industry Reports AKGeology.info Rare Earth Elements WebGeochem Engineering Geology Alaska Fairbanks and is currently working toward becoming a certified GIS professional. Position: GIS Analyst professional. Professional Experience 2013-present - Cartographer/GIS Analyst, State of Alaska, Division of
33 CFR 211.24 - Disposition of claims.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Section 211.24 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE REAL ESTATE ACTIVITIES OF THE CORPS OF ENGINEERS IN CONNECTION WITH CIVIL WORKS PROJECTS Real... damages not exceeding $1,000 may be settled by the Division Engineer. If the Division Engineer allows the...
Eileen Dimond, RN, MS | Division of Cancer Prevention
Eileen Dimond is a nurse consultant in the Division of Cancer Prevention. She works with the NCI community oncology programs and the sites that form the community network across the U.S. and in Hawaii with a focus on clinical trial infrastructure and implementation in the community. |
ERIC Educational Resources Information Center
Palter Gill, Dianne
2012-01-01
Despite the importance of effective linkages between credit and noncredit divisions, significant barriers interfere with and detract from these units working well together. Community college leaders are challenged to manage these multiple and sometimes competing organizational identities in a complex and rapidly-changing educational landscape.…
33 CFR 211.22 - Real estate Claims Officers.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Real estate Claims Officers. 211..., DEPARTMENT OF DEFENSE REAL ESTATE ACTIVITIES OF THE CORPS OF ENGINEERS IN CONNECTION WITH CIVIL WORKS PROJECTS Real Estate Claims § 211.22 Real estate Claims Officers. In each Division Office the Division...
33 CFR 211.22 - Real estate Claims Officers.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Real estate Claims Officers. 211..., DEPARTMENT OF DEFENSE REAL ESTATE ACTIVITIES OF THE CORPS OF ENGINEERS IN CONNECTION WITH CIVIL WORKS PROJECTS Real Estate Claims § 211.22 Real estate Claims Officers. In each Division Office the Division...
33 CFR 211.22 - Real estate Claims Officers.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Real estate Claims Officers. 211..., DEPARTMENT OF DEFENSE REAL ESTATE ACTIVITIES OF THE CORPS OF ENGINEERS IN CONNECTION WITH CIVIL WORKS PROJECTS Real Estate Claims § 211.22 Real estate Claims Officers. In each Division Office the Division...
33 CFR 211.22 - Real estate Claims Officers.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Real estate Claims Officers. 211..., DEPARTMENT OF DEFENSE REAL ESTATE ACTIVITIES OF THE CORPS OF ENGINEERS IN CONNECTION WITH CIVIL WORKS PROJECTS Real Estate Claims § 211.22 Real estate Claims Officers. In each Division Office the Division...
DOE Office of Scientific and Technical Information (OSTI.GOV)
EHS Staff
2003-04-01
To ensure efficient and effective management of LBNL facilities, LBNL shall assign line managers to perform appropriate work functions. LBNL divisions that are delegated responsibility for the management of buildings shall designate division personnel to serve as --''Building Managers.''
Spatial Ability Improvement and Curriculum Content
ERIC Educational Resources Information Center
Connolly, Patrick E.
2009-01-01
There has been a significant history of research on spatial ability and visualization improvement and related curriculum content presented by members of the Engineering Design Graphics Division over the past decade. Recently, interest in this topic has again been heightened thanks to the work of several division members on research such as the…
Mazerolle, Stephanie M; Goodman, Ashley; Pitney, William A
2015-01-01
Supervisor support has been identified as key to the fulfillment of work-life balance for the athletic trainer (AT), yet limited literature exists on the perspectives of supervisors. To investigate how the head AT facilitates work-life balance among staff members within the National Collegiate Athletic Association Division I setting. Qualitative study. Web-based management system. A total of 18 head ATs (13 men, 5 women; age = 44 ± 8 years, athletic training experience = 22 ± 7 years) volunteered for an asynchronous, Web-based interview. Participants responded to a series of questions by journaling their thoughts and experiences. We included multiple-analyst triangulation, stakeholder checks, and peer review to establish data credibility. We analyzed the data via a general inductive approach. Four prevailing themes emerged from the data: modeling work-life balance, encouraging disengagement from the AT role, cooperation and community workplace, and administrative support and understanding. Head ATs at the Division I level recognized the need to promote work-life balance among their staffs. They not only were supportive of policies that promote work-life balance, including spending time away from the role of the AT and teamwork among staff members, but also modeled and practiced the strategies that they promoted.
ERIC Educational Resources Information Center
International Federation of Library Associations, The Hague (Netherlands).
The seven papers in this collection continue the presentations from the Division of Libraries Serving the General Public: (1) "Multicultural Activities for Children and Young People at the Munich International Youth Library" (German and English versions; Lioba Betten); (2) "Multicultural Literature and Library Services for Children:…
Dynamic self-organisation of haematopoiesis and (a)symmetric cell division.
Måløy, Marthe; Måløy, Frode; Jakobsen, Per; Olav Brandsdal, Bjørn
2017-02-07
A model of haematopoiesis that links self-organisation with symmetric and asymmetric cell division is presented in this paper. It is assumed that all cell divisions are completely random events, and that the daughter cells resulting from symmetric and asymmetric stem cell divisions are, in general, phenotypically identical, and still, the haematopoietic system has the flexibility to self-renew, produce mature cells by differentiation, and regenerate undifferentiated and differentiated cells when necessary, due to self-organisation. As far as we know, no previous model implements symmetric and asymmetric division as the result of self-organisation. The model presented in this paper is inspired by experiments on the Drosophila germline stem cell, which imply that under normal conditions, the stem cells typically divide asymmetrically, whereas during regeneration, the rate of symmetric division increases. Moreover, the model can reproduce several of the results from experiments on female Safari cats. In particular, the model can explain why significant fluctuation in the phenotypes of haematopoietic cells was observed in some cats, when the haematopoietic system had reached normal population level after regeneration. To our knowledge, no previous model of haematopoiesis in Safari cats has captured this phenomenon. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.
Human bipedalism and body-mass index.
Yi, Su Do; Noh, Jae Dong; Minnhagen, Petter; Song, Mi-Young; Chon, Tae-Soo; Kim, Beom Jun
2017-06-16
Body-mass index, abbreviated as BMI and given by M/H 2 with the mass M and the height H, has been widely used as a useful proxy to measure a general health status of a human individual. We generalise BMI in the form of M/H p and pursue to answer the question of the value of p for populations of animal species including human. We compare values of p for several different datasets for human populations with the ones obtained for other animal populations of fish, whales, and land mammals. All animal populations but humans analyzed in our work are shown to have p ≈ 3 unanimously. In contrast, human populations are different: As young infants grow to become toddlers and keep growing, the sudden change of p is observed at about one year after birth. Infants younger than one year old exhibit significantly larger value of p than two, while children between one and five years old show p ≈ 2, sharply different from other animal species. The observation implies the importance of the upright posture of human individuals. We also propose a simple mechanical model for a human body and suggest that standing and walking upright should put a clear division between bipedal human (p ≈ 2) and other animals (p ≈ 3).
NASA Astrophysics Data System (ADS)
Sutter, Leo; Kolbman, Dan; Wu, Mingming; Ma, Minglin; Das, Moumita
The biophysics of cell co-cultures, i.e. binary systems of cell populations, is of great interest in many biological processes including formation of embryos, and tumor progression. During these processes, different types of cells with different physical properties are mixed with each other, with important consequences for cell-cell interaction, aggregation, and migration. The role of the differences in their physical properties in their collective behavior remains poorly understood. Furthermore, until recently most theoretical studies of collective cell migration have focused on two dimensional systems. Under physiological conditions, however, cells often have to navigate three dimensional and confined micro-environments. We study a confined, three-dimensional binary system of interacting, active, and deformable particles with different physical properties such as deformability, motility, adhesion, and division rates using Langevin Dynamics simulations. Our findings may provide insights into how the differences in and interplay between cell mechanical properties, division, and motility influence emergent collective behavior such as cell aggregation and segregation experimentally observed in co-cultures of breast cancer cells and healthy breast epithelial cells. This work was partially supported by a Cottrell College Science Award.
Long life technology work at Rockwell International Space Division
NASA Technical Reports Server (NTRS)
Huzel, D. K.
1974-01-01
This paper presents highlights of long-life technology oriented work performed at the Space Division of Rockwell International Corporation under contract to NASA. This effort included evaluation of Saturn V launch vehicle mechanical and electromechanical components for potential extended life capabilities, endurance tests, and accelerated aging experiments. A major aspect was evaluation of the components at the subassembly level (i.e., at the interface between moving surfaces) through in-depth wear analyses and assessments. Although some of this work is still in progress, preliminary conclusions are drawn and presented, together with the rationale for each. The paper concludes with a summary of the effort still remaining.
Occupational exposure to coal tar pitch volatiles, benzo/a/pyrene and dust in tyre production.
Rogaczewska, T; Ligocka, D
1994-01-01
Occupational exposure to coal tar pitch volatiles (CTPVs), benzo/a/pyrene (BaP) and dust was evaluated by means of individual measurements carried out in 80 workers and by stationary measurements on 16 work-posts in two divisions of the tyre producing plant. Dust and coal tar pitch volatiles concentrations in the air were determinated by the gravimetric method, measured, in the case of CPTVs, benzene-soluble fraction (BSF) with ultrasonic extraction. Benzo/a/pyrene analysis was performed using high performance liquid chromato-graphy (HPLC) with a spectrofluorimetric detector. It was found that nearly all personal sampling results for BaP were within the range < 4 divided by 142 ng/m3, except for the exposure of workers employed at weighing the raw materials (3,470-6,060 ng/m3) in the Semiproducts Division. Attention should be paid to the recorded CTPVs concentrations (benzene solubles). About 56% of the Vulcanizing Division workers and about 90% of the Semiproducts Division workers were exposed to these substances at concentrations of over 0.2 mg/m3 (hygienic standard for benzene solubles in USA). Exposure to dust (of high respirable fraction percentage > 90%) which exceeded the admissible value (4 mg/m3) was found mainly only in the workers of the Semiproducts Division at some work-posts.
Activities of the Structures Division, Lewis Research Center
NASA Technical Reports Server (NTRS)
1990-01-01
The purpose of the NASA Lewis Research Center, Structures Division's 1990 Annual Report is to give a brief, but comprehensive, review of the technical accomplishments of the Division during the past calendar year. The report is organized topically to match the Center's Strategic Plan. Over the years, the Structures Division has developed the technology base necessary for improving the future of aeronautical and space propulsion systems. In the future, propulsion systems will need to be lighter, to operate at higher temperatures and to be more reliable in order to achieve higher performance. Achieving these goals is complex and challenging. Our approach has been to work cooperatively with both industry and universities to develop the technology necessary for state-of-the-art advancement in aeronautical and space propulsion systems. The Structures Division consists of four branches: Structural Mechanics, Fatigue and Fracture, Structural Dynamics, and Structural Integrity. This publication describes the work of the four branches by three topic areas of Research: (1) Basic Discipline; (2) Aeropropulsion; and (3) Space Propulsion. Each topic area is further divided into the following: (1) Materials; (2) Structural Mechanics; (3) Life Prediction; (4) Instruments, Controls, and Testing Techniques; and (5) Mechanisms. The publication covers 78 separate topics with a bibliography containing 159 citations. We hope you will find the publication interesting as well as useful.
Iwai, Sosuke; Fujiwara, Kenji; Tamura, Takuro
2016-09-01
Algal endosymbiosis is widely distributed in eukaryotes including many protists and metazoans, and plays important roles in aquatic ecosystems, combining phagotrophy and phototrophy. To maintain a stable symbiotic relationship, endosymbiont population size in the host must be properly regulated and maintained at a constant level; however, the mechanisms underlying the maintenance of algal endosymbionts are still largely unknown. Here we investigate the population dynamics of the unicellular ciliate Paramecium bursaria and its Chlorella-like algal endosymbiont under various experimental conditions in a simple culture system. Our results suggest that endosymbiont population size in P. bursaria was not regulated by active processes such as cell division coupling between the two organisms, or partitioning of the endosymbionts at host cell division. Regardless, endosymbiont population size was eventually adjusted to a nearly constant level once cells were grown with light and nutrients. To explain this apparent regulation of population size, we propose a simple mechanism based on the different growth properties (specifically the nutrient requirements) of the two organisms, and based from this develop a mathematical model to describe the population dynamics of host and endosymbiont. The proposed mechanism and model may provide a basis for understanding the maintenance of algal endosymbionts. © 2015 Society for Applied Microbiology and John Wiley & Sons Ltd.
Egf Signaling Directs Neoblast Repopulation by Regulating Asymmetric Cell Division in Planarians.
Lei, Kai; Thi-Kim Vu, Hanh; Mohan, Ryan D; McKinney, Sean A; Seidel, Chris W; Alexander, Richard; Gotting, Kirsten; Workman, Jerry L; Sánchez Alvarado, Alejandro
2016-08-22
A large population of proliferative stem cells (neoblasts) is required for physiological tissue homeostasis and post-injury regeneration in planarians. Recent studies indicate that survival of a few neoblasts after sublethal irradiation results in the clonal expansion of the surviving stem cells and the eventual restoration of tissue homeostasis and regenerative capacity. However, the precise mechanisms regulating the population dynamics of neoblasts remain largely unknown. Here, we uncovered a central role for epidermal growth factor (EGF) signaling during in vivo neoblast expansion mediated by Smed-egfr-3 (egfr-3) and its putative ligand Smed-neuregulin-7 (nrg-7). Furthermore, the EGF receptor-3 protein localizes asymmetrically on the cytoplasmic membrane of neoblasts, and the ratio of asymmetric to symmetric cell divisions decreases significantly in egfr-3(RNAi) worms. Our results not only provide the first molecular evidence of asymmetric stem cell divisions in planarians, but also demonstrate that EGF signaling likely functions as an essential regulator of neoblast clonal expansion. Copyright © 2016 Elsevier Inc. All rights reserved.
Radiosensitivity of Mammalian Cells
Walters, R. A.; Petersen, D. F.
1968-01-01
Radiation effects on macromolecular synthesis essential for the Chinese hamster cell to traverse the life cycle and to divide have been investigated. Life-cycle analysis techniques employing inhibitors of macromolecular synthesis were used in determining the kinetics of cell growth for specific segments of the population following spontaneous recovery from radiation-induced division delay. The results indicated that recovery does not occur in the absence of functional protein synthesis. Under conditions which inhibit normal RNA and DNA synthesis, irradiated cells can recover the capacity to traverse the life cycle and to divide. The stability of mRNA species coding for proteins essential for division in irradiated cells was also measured. The mean functional lifetime of these mRNA species was 1 hr. The data demonstrate the existence of a specific segment of the population consisting of cells which have completed transcription related to division but not concomitant translation and which can recover from the radiation injury without synthesis of additional RNA. Thus, initial recovery of the ability to divide has an obligate requirement for protein synthesis but no corresponding requirement for nucleic acid synthesis during the period when original messenger remains intact. PMID:5753224
Berntsson, L; Lundberg, U; Krantz, G
2006-01-01
Objective To analyse gender differences in paid and unpaid workload and symptoms in matched groups of Swedish white‐collar workers with children. Design and setting Paid and unpaid workload and perceived stress from paid work, conflict between demands and control over household work were measured by a total workload (TWL) questionnaire. Some symptoms were rated with regard to frequency and severity as a measure of health. Cross‐sectional analyses were performed. Participants Matched groups of male (n = 440) and female (n = 529) well‐educated white‐collar workers in full‐time employment, aged 32–58 years and living with children in the home. Results Women in higher positions in Sweden are healthier than the average population of women, but report more symptoms than men in the same position as well as more stress from paid work, more conflict between demands and a greater TWL. However, women also reported more control over household duties and TWL was not associated with more symptoms. The men were mainly focused on their paid work role and perhaps even more so than men in the general population as they were fairly resistant to feelings of conflicting demands. Conclusion Even among matched groups of full‐time employed, well‐educated men and women, traditional gender differences in division of responsibilities and time allocation were found. Even though the women were healthy at this stage, they might risk future ill health, owing to high workload, stress and feelings of conflicting demands. PMID:17108304
A New Division of Labor: Meeting America’s Security Challenges Beyond Iraq
2007-01-01
on North Korea’s nuclear capabilities, see Graham and Kessler (2005). 20 A New Division of Labor most populous country, China has over the past... Seth Jones, Rollie Lal, Andrew Rathmell, and Anga Timilsina, America’s Role in Nation-Building: From Germany to Iraq, Santa Monica, Calif.: RAND...Graham, Bradley, and Glenn Kessler , “N. Korea Nuclear Advance is Cited,” Washington Post, April 29, 2005, p. 1. Bibliography 107 Headquarters
ERIC Educational Resources Information Center
International Federation of Library Associations and Institutions, London (England).
Eleven papers delivered at the annual meeting of the International Federation of Library Associations and Institutions for the Division of Management and Technology are presented. Some were presented at a roundtable on audiovisual media, and others are from sessions on library buildings and equipment, information management, and statistics in…
Gain control through divisive inhibition prevents abrupt transition to chaos in a neural mass model
Papasavvas, Christoforos A.; Wang, Yujiang; Trevelyan, Andrew J.; Kaiser, Marcus
2016-01-01
Experimental results suggest that there are two distinct mechanisms of inhibition in cortical neuronal networks: subtractive and divisive inhibition. They modulate the input-output function of their target neurons either by increasing the input that is needed to reach maximum output or by reducing the gain and the value of maximum output itself, respectively. However, the role of these mechanisms on the dynamics of the network is poorly understood. We introduce a novel population model and numerically investigate the influence of divisive inhibition on network dynamics. Specifically, we focus on the transitions from a state of regular oscillations to a state of chaotic dynamics via period-doubling bifurcations. The model with divisive inhibition exhibits a universal transition rate to chaos (Feigenbaum behavior). In contrast, in an equivalent model without divisive inhibition, transition rates to chaos are not bounded by the universal constant (non-Feigenbaum behavior). This non-Feigenbaum behavior, when only subtractive inhibition is present, is linked to the interaction of bifurcation curves in the parameter space. Indeed, searching the parameter space showed that such interactions are impossible when divisive inhibition is included. Therefore, divisive inhibition prevents non-Feigenbaum behavior and, consequently, any abrupt transition to chaos. The results suggest that the divisive inhibition in neuronal networks could play a crucial role in keeping the states of order and chaos well separated and in preventing the onset of pathological neural dynamics. PMID:26465514
Diverse behaviors of outer radial glia in developing ferret and human cortex.
Gertz, Caitlyn C; Lui, Jan H; LaMonica, Bridget E; Wang, Xiaoqun; Kriegstein, Arnold R
2014-02-12
The dramatic increase in neocortical size and folding during mammalian brain evolution has been attributed to the elaboration of the subventricular zone (SVZ) and the associated increase in neural progenitors. However, recent studies have shown that SVZ size and the abundance of resident progenitors do not directly predict cortical topography, suggesting that complex behaviors of the progenitors themselves may contribute to the overall size and shape of the adult cortex. Using time-lapse imaging, we examined the dynamic behaviors of SVZ progenitors in the ferret, a gyrencephalic carnivore, focusing our analysis on outer radial glial cells (oRGs). We identified a substantial population of oRGs by marker expression and their unique mode of division, termed mitotic somal translocation (MST). Ferret oRGs exhibited diverse behaviors in terms of division location, cleavage angle, and MST distance, as well as fiber orientation and dynamics. We then examined the human fetal cortex and found that a subset of human oRGs displayed similar characteristics, suggesting that diversity in oRG behavior may be a general feature. Similar to the human, ferret oRGs underwent multiple rounds of self-renewing divisions but were more likely to undergo symmetric divisions that expanded the oRG population, as opposed to producing intermediate progenitor cells (IPCs). Differences in oRG behaviors, including proliferative potential and daughter cell fates, may contribute to variations in cortical structure between mammalian species.
78 FR 72717 - Division of Coal Mine Workers' Compensation; Proposed Collection; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-03
... DEPARTMENT OF LABOR Office of Workers' Compensation Programs Division of Coal Mine Workers... proposed collection: Comparability of Current Work to Coal Mine Employment (CM-913). A copy of the proposed...., provides for the payment of benefits to coal miners who are totally disabled by black lung disease arising...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-14
..., Benton Harbor Division, Including On-Site Leased Workers of Aerotek and Penske Logistics, LLC, Benton... equipment. The company reports that workers leased from Penske Logistics, LLC, were employed on-site at the... from Penske Logistics, LLC working on-site at the Benton Harbor, Michigan location of Whirlpool...
Working Together: Strategy for Race Relations in Ontario.
ERIC Educational Resources Information Center
Ontario Human Rights Commission, Toronto.
The Ontario (Canada) Human Rights Commission seeks to promote a climate of human relations in the province which will allow all people to live together in harmony and enable individuals to fulfill their potential to the fullest degree. The Commission's Race Relations Division focuses on residual racist expressions and attitudes. This division's…
PARTICLE ACCELERATOR DIVISION SUMMARY REPORT FOR NOVEMBER 1958 THROUGH MAY 1959
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
Work in the division is summarized in the areas of theoretical studies, model magnet studies, ring magnet vacuum chamber, vacuum pumping system, ring magnet power supply, radio-frequency system, injection system, theoretical studies on radial motion through the linac, outgassing, and ferrite bonding. (For preceding period see ANL-5956.) (W.D.M.)
Educational Opportunities through Federal Assistance Programs, Fiscal 1974.
ERIC Educational Resources Information Center
Ohio State Dept. of Education, Columbus. Div. of Federal Assistance.
This publication, the ninth annual report of the Division of Federal Assistance of the Ohio Department of Education, summarizes the work of the division during fiscal 1974 (July 1, 1973-June 30, 1974). In addition to presenting statistical, fiscal, and graphic data, the report is designed to help educators and other interested persons to:…
Educational Opportunities through Federal Assistance Programs. Fiscal 1973.
ERIC Educational Resources Information Center
Ohio State Dept. of Education, Columbus. Div. of Federal Assistance.
This eighth annual report of the Division of Federal Assistance of the Ohio Department of Education, summarizes the work of the division during fiscal 1973. In addition to presenting statistical, fiscal, and graphic data, the report is designed to help educators and other interested persons understand the various Federal programs administered by…
ERIC Educational Resources Information Center
Gimbert, Tonya L.
2013-01-01
A review of the literature indicates an absence of studies about compliance officers working in higher education institutions belonging to the National Collegiate Athletic Association (NCAA). The current qualitative study explored the perceptions of compliance officers in the field of intercollegiate athletics at NCAA Division I institutions in…
Division of labour and the evolution of extreme specialization.
Cooper, Guy A; West, Stuart A
2018-05-28
Division of labour is a common feature of social groups, from biofilms to complex animal societies. However, we lack a theoretical framework that can explain why division of labour has evolved on certain branches of the tree of life but not others. Here, we model the division of labour over a cooperative behaviour, considering both when it should evolve and the extent to which the different types should become specialized. We found that: (1) division of labour is usually-but not always-favoured by high efficiency benefits to specialization and low within-group conflict; and (2) natural selection favours extreme specialization, where some individuals are completely dependent on the helping behaviour of others. We make a number of predictions, several of which are supported by the existing empirical data, from microbes and animals, while others suggest novel directions for empirical work. More generally, we show how division of labour can lead to mutual dependence between different individuals and hence drive major evolutionary transitions, such as those to multicellularity and eusociality.
Staff survey of organizational structure and process for a Public Health Department.
Dwyer, J J
1995-01-01
A survey of 227 North York Public Health Department (NYPHD) staff provided their perspective on the organizational structure. They perceived that (a) the departmental and divisional organizational structures are effective for program delivery, (b) the Central Resources structure and divisional and departmental reporting structures are moderately effective for program delivery, (c) the decentralized office structure is an advantage for service delivery but less so for administration and intra-division and inter-division communication, (d) the mandatory program structure involves low to moderate interdisciplinary teamwork and moderately impacts service delivery, (e) intra-division and management-staff communication are fair but inter-division and office communication are between poor and fair, (f) education, research, and service are moderately integrated, and (g) the divisional and departmental work atmospheres are a little positive. Management perceived greater participation in program planning, more frequent communication with other divisions, a number of education and research opportunities from various divisions/units, and more management recognition than front line staff did.
Mentorship programs for faculty development in academic general pediatric divisions.
Takagishi, Jennifer; Dabrow, Sharon
2011-01-01
Introduction. Mentoring relationships have been shown to support academicians in areas of research, work/life balance, and promotion. Methods. General pediatric division chiefs accessed an electronic survey asking about mentorship relationships, their ability to create a mentorship program, and resources needed. Results. Dyadic mentorship programs were available at 53% of divisions. Peer mentorship programs were available at 27% of divisions. Overall, 84% of chiefs believed that dyadic mentorship would benefit their faculty. 91% of chiefs believed that peer mentorship would benefit their faculty. Chiefs were interested in starting peer (57%) or dyadic (55%) mentorship programs. Few divisions had a peer mentorship program available, whereas 24% already had a dyadic program. 43% of chiefs felt that they had the tools to start a program. Many tools are needed to create a program. Discussion. General pediatric division chiefs acknowledge the benefits of mentoring relationships, and some have programs in place. Many need tools to create them. Pediatric societies could facilitate this critical area of professional development.
ERIC Educational Resources Information Center
Kraenzel, Carl F.
Rural demographic characteristics, regional distribution, and their respective trends should constitute significant policy information for the nation, but the U.S. Population Census offers little aid to the researcher studying population on a minor civil division (MCD) basis. When some census data are based on a 15 percent sample, some on a 5…
[Prospect and application of microsatellite population genetics in study of geoherbs].
Zhang, Wen-Jing; Zhang, Yong-Qing; Yuan, Qing-Jun; Huang, Lu-Qi; Jiang, Dan; Jing, Li
2013-12-01
The author introduces the basic concepts of microsatellite and population genetics and its characteristics, expounds the application of these theories for population genetic structure and genetic diversity, gene flow and evolutionary significant unit ESU division research. This paper discuss its applicationin study of genetic causes, origin of cultivation, different regional origins of geoherbs, aiming at providing a new theory and method for geoherbs.
Luis de Florez and the Special Devices Division
NASA Astrophysics Data System (ADS)
Dawson, Paul Louis
This Dissertation presents the life of Luis de Florez and the World War II history of the Special Devices Division (SDD) of the U.S. Navy's Bureau of Aeronautics. Luis de Florez was a well known consulting engineer, aviation fuel expert, private pilot and reserve Naval officer. While on active duty in 1940, he received the assignment to improve the Navy's flight training methods. To accomplish this objective, he promoted the concept of synthetic training, the use of simulators and other non-operational equipment, to provide training for Navy flight personnel such as pilots, gunners, navigators, flight engineers, radio operators and others as well as for ground based people like mechanics. He founded the Special Devices Division to design the tools and equipment needed for this type of training. The success of synthetic training and the devices developed by the SDD received recognition by the awarding of the Collier Trophy to de Florez in December 1944. This trophy is awarded annually for the most significant aeronautical achievement of the previous year (1943). De Florez received the award for the strategic accomplishment of training thousands of American airmen in 1943. The work of the Division also had other important technical, social, financial and operational impacts on the prosecution of WW II by the Allies. The work of the Division also had impacts on American society as a whole that persist to the present day. These impacts are discussed in detail. The Dissertation presents details of the devices and their use in aviation training as well as a history of the Division during the war. After the war, de Florez led an advisory board for the CIA. These activities and some of both the positive and negative results of the work of this board are discussed. This discussion includes de Florez' involvement in the CIA's drug experiments and the unfortunate Frank Olsen affair.
AAPG forms environmental unit; Geosat moving
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1992-07-20
This paper reports that the American Association of Petroleum Geologists has established a new environmental geology division, while a geology related committee is moving from Oklahoma. AAPG set up a Division of Environmental Geosciences to provide services and information to its members working in environmental geosciences, the Bernold M. Bruno Hanson of Midland, Tex., the DEG's first president. The division will publish a newsletter in October, and plans are being set to solicit technical articles for consideration by the AAPG Bulletin and for a possible future separate DEG technical publication.
1990-09-01
TELEPHONE (Include Area Code) 22c OFFICE SYMBOL WILLIAM J. HANSEN (703) 355-3089 CEWRC-IWR-R DD FORM 1473, 84 MAR 83 APR edition may be used until... William J. Hansen of the Institute for Water Resources was the Technical Study Manager. Mr. L. Leigh Skaggs of the Institute for Water Resources...Mr. William Thornton, Missouri River Division, Mr. Bruce Hardie, Southwestern Division and Mr. Allen Summers, North Pacific Division. U.S. ARMY
Syed, I; Daly, T; Armstrong, P; Lowndes, R; Chadoin, M; Naidoo, V
2016-01-01
According to the Canadian Health Care Association (1), there are 2,577 long-term care ("LTC") facilities across Canada, with the largest proportion (33.4%) located in Ontario. Most studies focus on residents' health, with less attention paid to the health and safety experiences of staff. Given that the work performed in Ontario LTC facilities is very gendered, increasingly racialized, task-oriented, and with strict divisions of labour, this paper explores in what ways some of these factors impact workers' experiences of health and safety. The study objectives included the following research question: How are work hierarchies and task orientation experienced by staff? This paper draws on data from rapid team-based ethnographies of the shifting division of labour in LTC due to use of informal carers in six non-profit LTC facilities located in Toronto, Ontario. Our method involved conducting observations and key informant interviews (N=167) with registered nurses, registered practical nurses, personal support workers, dietary aides, recreation therapists, families, privately paid companions, students, and volunteers. Interviews were audio-recorded, transcribed verbatim, and thematically analyzed. For observations, researchers were paired and covered shifts between 7 a.m. and 11 p.m., as well as into the late night over six days, at each of the six sites. Detailed ethnographic field notes were written during and immediately following observational fieldwork. Our results indicate that employee stress is linked to the experiences of care work hierarchies, task orientation, and strict divisions of labour between and among various staff designations. Findings from this project confirm and extend current research that demonstrates there are challenging working conditions in LTC, which can result in occupational health and safety problems, as well as stress for individual workers.
29 CFR 785.44 - Civic and charitable work.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR INTERPRETATION NOT DIRECTLY RELATED TO REGULATIONS HOURS WORKED Application of Principles... working time. However, time spent voluntarily in such activities outside of the employee's normal working...
A single molecule perspective on the functional diversity of in vitro evolved β-glucuronidase.
Liebherr, Raphaela B; Renner, Max; Gorris, Hans H
2014-04-23
The mechanisms that drive the evolution of new enzyme activity have been investigated by comparing the kinetics of wild-type and in vitro evolved β-glucuronidase (GUS) at the single molecule level. Several hundred single GUS molecules were separated in large arrays of 62,500 ultrasmall reaction chambers etched into the surface of a fused silica slide to observe their individual substrate turnover rates in parallel by fluorescence microscopy. Individual GUS molecules feature long-lived but divergent activity states, and their mean activity is consistent with classic Michaelis-Menten kinetics. The large number of single molecule substrate turnover rates is representative of the activity distribution within an entire enzyme population. Partially evolved GUS displays a much broader activity distribution among individual enzyme molecules than wild-type GUS. The broader activity distribution indicates a functional division of work between individual molecules in a population of partially evolved enzymes that-as so-called generalists-are characterized by their promiscuous activity with many different substrates.
The BMC ACCESS project: the development of a medically enhanced safe haven shelter.
Lincoln, Alisa; Johnson, Peggy; Espejo, Dennis; Plachta-Elliott, Sara; Lester, Peggy; Shanahan, Christopher; Abbott, Susan; Cabral, Howard; Jamanka, Amber; Delman, Jonathan; Kenny, Patty
2009-10-01
This paper describes the development and implementation of the Boston Medical Center (BMC) Advanced Clinical Capacity for Engagement, Safety, and Services Project. In October 2002, the BMC Division of Psychiatry became the first such entity to open a Safe Haven shelter for people who are chronically homeless, struggling with severe mental illness, and actively substance abusing. The low-demand Safe Haven model targets the most difficult to reach population and serves as a "portal of entry" to the mental health and addiction service systems. In this paper, the process by which this blended funded, multi-level collaboration, consisting of a medical center, state, city, local, and community-based consumer organizations, was created and is maintained, as well as the clinical model of care is described. Lessons learned from creating the Safe Haven Shelter and the development and implementation of the consumer-informed evaluation are discussed as well as implications for future work with this population.
Rasnick, David
2002-07-01
The autocatalyzed progression of aneuploidy accounts for all cancer-specific phenotypes, the Hayflick limit of cultured cells, carcinogen-induced tumors in mice, the age distribution of human cancer, and multidrug-resistance. Here aneuploidy theory addresses tumor formation. The logistic equation, phi(n)(+1) = rphi(n) (1 - phi(n)), models the autocatalyzed progression of aneuploidy in vivo and in vitro. The variable phi(n)(+1) is the average aneuploid fraction of a population of cells at the n+1 cell division and is determined by the value at the nth cell division. The value r is the growth control parameter. The logistic equation was used to compute the probability distribution for values of phi after numerous divisions of aneuploid cells. The autocatalyzed progression of aneuploidy follows the laws of deterministic chaos, which means that certain values of phi are more probable than others. The probability map of the logistic equation shows that: 1) an aneuploid fraction of at least 0.30 is necessary to sustain a population of cancer cells; and 2) the most likely aneuploid fraction after many population doublings is 0.70, which is equivalent to a DNA(index)=1.7, the point of maximum disorder of the genome that still sustains life. Aneuploidy theory also explains the lack of immune surveillance and the failure of chemotherapy.
NASA Technical Reports Server (NTRS)
Mulhall, B. D. L.
1980-01-01
The results of the analysis of the external environment of the FBI Fingerprint Identification Division are presented. Possible trends in the future environment of the Division that may have an effect on the work load were projected to determine if future work load will lie within the capability range of the proposed new system, AIDS 3. Two working models of the environment were developed, the internal and external model, and from these scenarios the projection of possible future work load volume and mixture was developed. Possible drivers of work load change were identified and assessed for upper and lower bounds of effects. Data used for the study were derived from historical information, analysis of the current situation and from interviews with various agencies who are users of or stakeholders in the present system.
Mazerolle, Stephanie M.; Goodman, Ashley; Pitney, William A.
2015-01-01
Context: Supervisor support has been identified as key to the fulfillment of work-life balance for the athletic trainer (AT), yet limited literature exists on the perspectives of supervisors. Objective: To investigate how the head AT facilitates work-life balance among staff members within the National Collegiate Athletic Association Division I setting. Design: Qualitative study. Setting: Web-based management system. Patients or Other Participants: A total of 18 head ATs (13 men, 5 women; age = 44 ± 8 years, athletic training experience = 22 ± 7 years) volunteered for an asynchronous, Web-based interview. Data Collection and Analysis: Participants responded to a series of questions by journaling their thoughts and experiences. We included multiple-analyst triangulation, stakeholder checks, and peer review to establish data credibility. We analyzed the data via a general inductive approach. Results: Four prevailing themes emerged from the data: modeling work-life balance, encouraging disengagement from the AT role, cooperation and community workplace, and administrative support and understanding. Conclusions: Head ATs at the Division I level recognized the need to promote work-life balance among their staffs. They not only were supportive of policies that promote work-life balance, including spending time away from the role of the AT and teamwork among staff members, but also modeled and practiced the strategies that they promoted. PMID:25343530
NCI Community Oncology Research Program (NCORP) | Division of Cancer Prevention
The NCI Community Oncology Research Program (NCORP) is a national network of cancer care investigators, providers, academia, and other organizations that care for diverse populations in health systems. View the list of publications from NCORP. | Clinical Trials network of cancer care professionals who care for diverse populations across the U.S.
Ethnobiology in the city: Embracing the urban ecological moment
Marla R. Emery; Patrick T. Hurley
2016-01-01
More than half the world's human population resides in cities (United Nations Economic and Social Affairs Population Division 2015)1. Unpacking this singular statistic, it becomes clear that people come to live in urban environments via numerous routes. Some have lived in cities all their lives and are descendants of city dwellers. In other...
Comparison of tumor biology of two distinct cell sub-populations in lung cancer stem cells.
Wang, Jianyu; Sun, Zhiwei; Liu, Yongli; Kong, Liangsheng; Zhou, Shixia; Tang, Junlin; Xing, Hongmei Rosie
2017-11-14
Characterization of the stem-like properties of cancer stem cells (CSCs) remain indirect and qualitative, especially the ability of CSCs to undergo asymmetric cell division for self renewal and differentiation, a unique property of cells of stem origin. It is partly due to the lack of stable cellular models of CSCs. In this study, we developed a new approach for CSC isolation and purification to derive a CSC-enriched cell line (LLC-SE). By conducting five consecutive rounds of single cell cloning using the LLC-SE cell line, we obtained two distinct sub-population of cells within the Lewis lung cancer CSCs that employed largely symmetric division for self-renewal (LLC-SD) or underwent asymmetric division for differentiation (LLC-ASD). LLC-SD and LLC-ASD cell lines could be stably passaged in culture and be distinguished by cell morphology, stem cell marker, spheroid formation and subcutaneous tumor initiation efficiency, as well as orthotopic lung tumor growth, progression and survival. The ability LLC-ASD cells to undergo asymmetric division was visualized and quantified by the asymmetric segregation of labeled BrdU and NUMB to one of the two daughter cells in anaphase cell division. The more stem-like LLC-SD cells exhibited higher capacity for tumorigenesis and progression and shorter survival. As few as 10 LLC-SD could initiate subcutaneous tumor growth when transplanted to the athymic mice. Collectively, these observations suggest that the SD-type of cells appear to be on the top of the hierarchical order of the CSCs. Furthermore, they have lead to generated cellular models of CSC self-renewal for future mechanistic investigations.
Distinct temporal requirements for autophagy and the proteasome in yeast meiosis
Wen, Fu-Ping; Guo, Yue-Shuai; Hu, Yang; Liu, Wei-Xiao; Wang, Qian; Wang, Yuan-Ting; Yu, Hai-Yan; Tang, Chao-Ming; Yang, Jun; Zhou, Tao; Xie, Zhi-Ping; Sha, Jia-Hao; Guo, Xuejiang; Li, Wei
2016-01-01
ABSTRACT Meiosis is a special type of cellular renovation that involves 2 successive cell divisions and a single round of DNA replication. Two major degradation systems, the autophagy-lysosome and the ubiquitin-proteasome, are involved in meiosis, but their roles have yet to be elucidated. Here we show that autophagy mainly affects the initiation of meiosis but not the nuclear division. Autophagy works not only by serving as a dynamic recycling system but also by eliminating some negative meiotic regulators such as Ego4 (Ynr034w-a). In a quantitative proteomics study, the proteasome was found to be significantly upregulated during meiotic divisions. We found that proteasomal activity is essential to the 2 successive meiotic nuclear divisions but not for the initiation of meiosis. Our study defines the roles of autophagy and the proteasome in meiosis: Autophagy mainly affects the initiation of meiosis, whereas the proteasome mainly affects the 2 successive meiotic divisions. PMID:27050457
Distinct temporal requirements for autophagy and the proteasome in yeast meiosis.
Wen, Fu-ping; Guo, Yue-shuai; Hu, Yang; Liu, Wei-xiao; Wang, Qian; Wang, Yuan-ting; Yu, Hai-Yan; Tang, Chao-ming; Yang, Jun; Zhou, Tao; Xie, Zhi-ping; Sha, Jia-hao; Guo, Xuejiang; Li, Wei
2016-01-01
Meiosis is a special type of cellular renovation that involves 2 successive cell divisions and a single round of DNA replication. Two major degradation systems, the autophagy-lysosome and the ubiquitin-proteasome, are involved in meiosis, but their roles have yet to be elucidated. Here we show that autophagy mainly affects the initiation of meiosis but not the nuclear division. Autophagy works not only by serving as a dynamic recycling system but also by eliminating some negative meiotic regulators such as Ego4 (Ynr034w-a). In a quantitative proteomics study, the proteasome was found to be significantly upregulated during meiotic divisions. We found that proteasomal activity is essential to the 2 successive meiotic nuclear divisions but not for the initiation of meiosis. Our study defines the roles of autophagy and the proteasome in meiosis: Autophagy mainly affects the initiation of meiosis, whereas the proteasome mainly affects the 2 successive meiotic divisions.
Mudaliar, Umesh; Natutusau, Kinisimere; Pavluck, Alexandre L.; Willis, Rebecca; Alexander, Neal; Mabey, David C. W.; Cikamatana, Luisa; Kama, Mike; Rafai, Eric; Roberts, Chrissy H.; Solomon, Anthony W.
2016-01-01
Background Trachoma is the leading infectious cause of blindness and is caused by ocular infection with the bacterium Chlamydia trachomatis (Ct). While the majority of the global disease burden is found in sub-Saharan Africa, the Western Pacific Region has been identified as trachoma endemic. Population surveys carried out throughout Fiji have shown an abundance of both clinically active trachoma and trachomatous trichiasis in all divisions. This finding is at odds with the clinical experience of local healthcare workers who do not consider trachoma to be highly prevalent. We aimed to determine whether conjunctival infection with Ct could be detected in one administrative division of Fiji. Methods A population-based survey of 2306 individuals was conducted using the Global Trachoma Mapping Project methodology. Population prevalence of active trachoma in children and trichiasis in adults was estimated using the World Health Organization simplified grading system. Conjunctival swabs were collected from 1009 children aged 1–9 years. DNA from swabs was tested for the presence of the Ct plasmid and human endogenous control. Results The prevalence of active trachoma in 1–9 year olds was 3.4%. The age-adjusted prevalence was 2.8% (95% CI: 1.4–4.3%). The unadjusted prevalence of ocular Ct infection in 1–9 year-olds was 1.9% (19/1009), and the age-adjusted infection prevalence was 2.3% (95% CI: 0.4–2.5%). The median DNA load was 41 Ct plasmid copies per swab (min 20, first quartile 32, mean 6665, third quartile 161, max 86354). There was no association between current infection and follicular trachoma. No cases of trachomatous trichiasis were identified. Discussion The Western Division of Fiji has a low prevalence of clinical trachoma. Ocular Ct infections were observed, but they were predominantly low load infections and were not correlated with clinical signs. Our study data suggest that trachoma does not meet the WHO definition of a public health problem in this Division of Fiji, but the inconsistency with previous studies warrants further investigation. PMID:27404379
Macleod, Colin K; Butcher, Robert; Mudaliar, Umesh; Natutusau, Kinisimere; Pavluck, Alexandre L; Willis, Rebecca; Alexander, Neal; Mabey, David C W; Cikamatana, Luisa; Kama, Mike; Rafai, Eric; Roberts, Chrissy H; Solomon, Anthony W
2016-07-01
Trachoma is the leading infectious cause of blindness and is caused by ocular infection with the bacterium Chlamydia trachomatis (Ct). While the majority of the global disease burden is found in sub-Saharan Africa, the Western Pacific Region has been identified as trachoma endemic. Population surveys carried out throughout Fiji have shown an abundance of both clinically active trachoma and trachomatous trichiasis in all divisions. This finding is at odds with the clinical experience of local healthcare workers who do not consider trachoma to be highly prevalent. We aimed to determine whether conjunctival infection with Ct could be detected in one administrative division of Fiji. A population-based survey of 2306 individuals was conducted using the Global Trachoma Mapping Project methodology. Population prevalence of active trachoma in children and trichiasis in adults was estimated using the World Health Organization simplified grading system. Conjunctival swabs were collected from 1009 children aged 1-9 years. DNA from swabs was tested for the presence of the Ct plasmid and human endogenous control. The prevalence of active trachoma in 1-9 year olds was 3.4%. The age-adjusted prevalence was 2.8% (95% CI: 1.4-4.3%). The unadjusted prevalence of ocular Ct infection in 1-9 year-olds was 1.9% (19/1009), and the age-adjusted infection prevalence was 2.3% (95% CI: 0.4-2.5%). The median DNA load was 41 Ct plasmid copies per swab (min 20, first quartile 32, mean 6665, third quartile 161, max 86354). There was no association between current infection and follicular trachoma. No cases of trachomatous trichiasis were identified. The Western Division of Fiji has a low prevalence of clinical trachoma. Ocular Ct infections were observed, but they were predominantly low load infections and were not correlated with clinical signs. Our study data suggest that trachoma does not meet the WHO definition of a public health problem in this Division of Fiji, but the inconsistency with previous studies warrants further investigation.
Division F Commission 53: Extrasolar Planets
NASA Astrophysics Data System (ADS)
Lecavelier Des Etangs, Alain; Minniti, Dante; Boss, Alan; Mayor, Michel; Bodenheimer, Peter; Collier-Cameron, Andrew; Jayawardhana, Ray; Kokubo, Eiichiro; Mardling, Rosemary; Queloz, Didier; Rauer, Heike; Zhao, Gang
2016-04-01
The IAU Working Group on Extrasolar Planets (WGESP) was created by the Executive Council as a Working Group of Division III. This decision took place in June 1999, that is only 7 years after the discovery of planets around the pulsar PSR B1257+12 and 4 years after the discovery of 51 Peg b. This working group was renewed for 3 years at the General Assembly in 2003 in Sydney, Australia. It was chaired by Alan Boss from Carnegie Institution of Washington. The WGESP members were Paul Butler, William Hubbard, Philip Ianna, Martin Kürster, Jack Lissauer, Michel Mayor, Karen Meech, Francois Mignard, Alan Penny, Andreas Quirrenbach, Jill Tarter, and Alfred Vidal-Madjar.
2013-05-01
commercial and retail services to the military personnel on the Joint Base and the civilian population. The unemployment rate in New Hanover Township...Division of Banking and Insurance, the annual number of foreclosures in Burlington County increased steadily from 1,312 in 2005 to a high of 3,391 in...2009 (NJ Division of Banking , 2011). However, this annual figure represents only 1.9 percent of the total housing units in the County (US Census
An Evaluation of Sea Turtle Populations and Survival Status on Vieques Island.
1982-06-22
Pritchard T. H. Stubbs Florida Audubon Society (N66001-80-C-0560) 22 June 1982 Prepared for Marine Sciences Division Approved for public release...the Florida Audubon Society for NOSC Marine Sciences Division (Code 513). I Released by Under authority of S. Yamamoto. Head H.O. Porter. Head Marine ...Coollco so wo . i .0*W ow a AomY b block4 m.. Reptiles -. HawksbilIVieques Isand Loaesbsd Green turtle Nestn Turtles Loatharback 2 0. AGSTA ACT
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-18
... DEPARTMENT OF LABOR Office of Workers' Compensation Programs Division of Coal Mine Workers... comments concerning the proposed collection: Comparability of Current Work to Coal Mine Employment (CM-913... Benefits Act of 1977, as amended, 30 U.S.C. 901 et seq., provides for the payment of benefits to coal...
ERIC Educational Resources Information Center
Hicks, Katherine A.
2016-01-01
Fluorescence quenching assays are often used to measure dissociation constants that quantify the binding affinity between small molecules and proteins. In an upper-division undergraduate laboratory course, where students work on projects using a guided inquiry-based approach, a binding titration experiment at physiological pH is performed to…
2002-11-01
CRADAs) under which NRL scientists and engineers work together with industry , academia, state or local governments, or other Federal agencies to... industrial hygiene, and environ- mental safety. The Division provides engineering and technical assistance to research divisions in the installation...The NRL Women in Science and Engineer - ing (WISE) Network is an open-membership network group of scientists and engineers who meet periodically to
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-01
... Plant, Tyler, Texas. The notice was published in the Federal Register on December 11, 2009 (74 FR 65798...., Waterworks Division, South Plant, Tyler, Texas had their wages reported under a separate unemployment... Company, Waterworks Division, South Plant, Tyler, Texas (TA-W- 71,840A), who became totally or partially...
Attitudes toward Housework and Child Care and the Gendered Division of Labor
ERIC Educational Resources Information Center
Poortman, Anne-Rigt; van der Lippe, Tanja
2009-01-01
Research on the division of household labor has typically examined the role of time availability, relative resources, and gender ideology. We explore the gendered meaning of domestic work by examining the role of men's and women's attitudes toward household labor. Using data from the Dutch Time Competition Survey (N = 732), we find that women have…
Responding Logistically to Future Natural and Man-Made Disasters and Catastrophes
2008-03-15
Logistics Operations, Plans and Exercises, Distribution Management and Property Management. Each competency has associated roles, missions and...professional development. LMD’s Distribution Management Division (DMD) Within the LMD, FEMA also created the Distribution Management Division (DMD...to stock in anticipation of future disasters. A Distribution Management Strategy Working Group was formed with Federal, private and nongovernmental
16. The Baltimore & Ohio R.R System, Division BaltimoreEast, Bridge ...
16. The Baltimore & Ohio R.R System, Division Baltimore-East, Bridge No 13-A, Branch Philadelphia. Baltimore: Office of Engineer of Bridges, 1945. Copy of drawing located at the Baltimore County Department of Public Works, Towson, Maryland. - Allender Road Bridge, Spanning CSX Transportation railroad tracks at Allender Road, White Marsh, Baltimore County, MD
Women in Workplace: Vocational Education and Segregated Division of Labor.
ERIC Educational Resources Information Center
Lasonen, Johanna; Burge, Penny L.
The United States and Finland show a clear gender stratification in work life. The uneven, gender-biased division of labor has been maintained, even though about half of the total U.S. and Finnish labor force are women. In both countries, female students tend to make traditional occupational choices that prepare them for low-paying fields where…
ERIC Educational Resources Information Center
Westinghouse Electric Corp., Carlsbad, NM.
This module is part of a set of management and supervisor training (MAST) materials developed by the Department of Energy for the Waste Isolation Division. Its stated purpose is to enable trainees to organize work activities efficiently and effectively. The first section of the module is an introduction that includes a terminal objective and…
Cell division plane orientation based on tensile stress in Arabidopsis thaliana
Louveaux, Marion; Julien, Jean-Daniel; Mirabet, Vincent; Boudaoud, Arezki; Hamant, Olivier
2016-01-01
Cell geometry has long been proposed to play a key role in the orientation of symmetric cell division planes. In particular, the recently proposed Besson–Dumais rule generalizes Errera’s rule and predicts that cells divide along one of the local minima of plane area. However, this rule has been tested only on tissues with rather local spherical shape and homogeneous growth. Here, we tested the application of the Besson–Dumais rule to the divisions occurring in the Arabidopsis shoot apex, which contains domains with anisotropic curvature and differential growth. We found that the Besson–Dumais rule works well in the central part of the apex, but fails to account for cell division planes in the saddle-shaped boundary region. Because curvature anisotropy and differential growth prescribe directional tensile stress in that region, we tested the putative contribution of anisotropic stress fields to cell division plane orientation at the shoot apex. To do so, we compared two division rules: geometrical (new plane along the shortest path) and mechanical (new plane along maximal tension). The mechanical division rule reproduced the enrichment of long planes observed in the boundary region. Experimental perturbation of mechanical stress pattern further supported a contribution of anisotropic tensile stress in division plane orientation. Importantly, simulations of tissues growing in an isotropic stress field, and dividing along maximal tension, provided division plane distributions comparable to those obtained with the geometrical rule. We thus propose that division plane orientation by tensile stress offers a general rule for symmetric cell division in plants. PMID:27436908
Optimizing homeostatic cell renewal in hierarchical tissues
Fider, Nicole A.
2018-01-01
In order to maintain homeostasis, mature cells removed from the top compartment of hierarchical tissues have to be replenished by means of differentiation and self-renewal events happening in the more primitive compartments. As each cell division is associated with a risk of mutation, cell division patterns have to be optimized, in order to minimize or delay the risk of malignancy generation. Here we study this optimization problem, focusing on the role of division tree length, that is, the number of layers of cells activated in response to the loss of terminally differentiated cells, which is related to the balance between differentiation and self-renewal events in the compartments. Using both analytical methods and stochastic simulations in a metapopulation-style model, we find that shorter division trees are advantageous if the objective is to minimize the total number of one-hit mutants in the cell population. Longer division trees on the other hand minimize the accumulation of two-hit mutants, which is a more likely evolutionary goal given the key role played by tumor suppressor genes in cancer initiation. While division tree length is the most important property determining mutant accumulation, we also find that increasing the size of primitive compartments helps to delay two-hit mutant generation. PMID:29447149
The IAU Division A Working Group on the Third Realization of the ICRF: Background, Goals, Plans
NASA Astrophysics Data System (ADS)
Gaume, Ralph
2015-08-01
The XXVIII General Assembly of the IAU (Beijing, 2012) established the Division A Working Group on the Third Realization of the International Celestial Reference Frame (ICRF). The adopted charter of the ICRF3 Working Group includes a commitment to report on the implementation and execution plans for ICRF3 during the XXIX General Assembly of the IAU along with a targeted completion and presentation of ICRF3 in 2018 to the XXX General Assembly for adoption. This talk will discuss the background, purpose, and overall implementation plan for ICRF3, and motivate the concept, currently under consideration by the ICRF3 Working Group, that future realizations of the ICRF be based on multi-frequency astrometric data, starting with ICRF3.
DOE Office of Scientific and Technical Information (OSTI.GOV)
McDonald, D.W.
1998-04-01
The ORNL I&C Division was created to support DOE-funded research. We have since broadened our mission to include other sponsors as the need for our services has grown. This report summarizes some of the work we have been conducting on behalf of DOE, other federal agencies, and the private sector during the past three and a half years. Because we take on nearly 750 individual projects every year, much of our work cannot be reported in detail. We hope that these summaries are of interest and demonstrate that our work, rooted in DOE scientific and technological programs, can also benefitmore » the nation, its industry, and its citizens in direct and tangible ways.« less
Optimal working zone division for safe track maintenance in The Netherlands.
den Hertog, D; van Zante-de Fokkert, J I; Sjamaar, S A; Beusmans, R
2005-09-01
After a sequence of serious accidents, the safety of rail track workers became an urgent and political problem in The Netherlands. It turned out that the rail track workers had one of the most dangerous jobs. The board of the Dutch Railways decided that the Dutch railway infrastructure had to be divided into so-called working zones. Moreover, to carry out maintenance activities, that particular working zone of the railway system had to be taken out of service. An essential problem was how to divide the Dutch railway infrastructure into working zones such that all parties involved are satisfied. Since many parties with conflicting interests were involved, this problem was extremely difficult. In this paper we show the division rules we developed, and which had been implemented in The Netherlands.
that the most acute and chronic conditions require a corresponding increased level of services intervention to acute psychiatric care. Included are services for the general population (prevention &
South Fork Salmon River Watershed Restoration, 2008-2009 Annual Report.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Reaney, Mark D.
2009-04-15
The watershed restoration work elements within the project area, the South Fork Salmon River Watershed, follow the watershed restoration approach adopted by the Nez Perce Tribe Department of Fisheries Resource Management (DFRM) - Watershed Division. The vision of the Nez Perce Tribe DFRM-Watershed Division focuses on protecting, restoring, and enhancing watersheds and treaty resources within the ceded territory of the Nez Perce Tribe under the Treaty of 1855 with the United States Federal Government. The program uses a holistic approach, which encompasses entire watersheds, ridge top to ridge top, emphasizing all cultural aspects and strategies that rely on natural fishmore » production and healthy river ecosystems. The Nez Perce Tribe DFRM-Watershed Division strives towards maximizing historic ecosystem productivity and health for the restoration of anadromous and resident fish populations and the habitat on which all depend on for future generations Originally, this project was funded to create a step/pool stream channel that was appropriate to restore fish passage where the 'Glory Hole Cascade' is currently located at the Stibnite Mine. Due to unforeseen circumstances at the time, the project is unable to move forward as planned and a request for a change in scope of the project and an expansion of the geographic area in which to complete project work was submitted. No additional funds were being requested. The ultimate goal of this project is to work with the holistic, ridge top to ridge top approach to protect and restore the ecological and biological functions of the South Fork Salmon River Watershed to assist in the recovery of threatened and endangered anadromous and resident fish species. FY 2008 Work Elements included two aquatic organism passage (AOP) projects to restore habitat connectivity to two fish-bearing tributaries to the East Fork South Fork Salmon River, Salt and Profile Creeks. The Work Elements also included road survey and assessment activities that move toward road decommissioning to reduce sediment delivery to spawning gravels and rearing habitats by reducing sedimentation from road related, man-made sources. For FY08, the project included the design and implementation of two fish barrier replacement structures mentioned above, the Salt and Profile Creek Bridges. These work elements were to be implemented on Valley County easements within the Payette National Forest. The existing culverts are full or partial barriers to most aquatic life species and all juvenile anadromous and resident fish species. Implementation will reconnect 9.34 miles of habitat, and provide natural stream channels to facilitate complete passage for all aquatic life forms. All designs were completed and a construction subcontract was awarded to construct free span, pre-cast concrete bridges. For 2008, the project statement of work also included all the necessary work elements to manage, coordinate, plan, and develop continuing strategies for restoration and protection activities.« less
Fulfillment of Work-Life Balance From the Organizational Perspective: A Case Study.
Mazerolle, Stephanie M; Goodman, Ashley
2013-04-18
Researchers studying work-life balance have examined policy development and implementation to create a family-friendly work environment from an individualistic perspective rather than from a cohort of employees working under the same supervisor. To investigate what factors influence work-life balance within the National Collegiate Athletic Association (NCAA) Division I clinical setting from the perspective of an athletic training staff. Qualitative study. Web-based management system. Eight athletic trainers (5 men, 3 women; age = 38 ± 7 years) in the NCAA Division I setting. Participants responded to a series of questions by journaling their thoughts and experiences. We included data-source triangulation, multiple analyst triangulation, and peer review to establish data credibility. We analyzed the data via a grounded theory approach. Three themes emerged from the data. Family-oriented and supportive work environment was described as a workplace that fosters and encourages work-life balance through professionally and personally shared goals. Nonwork outlets included activities, such as exercise and personal hobbies, that provide time away from the role of the athletic trainer. Individualistic strategies reflected that although the athletic training staff must work together and support one another, each staff member must have his or her own personal strategies to manage personal and professional responsibilities. The foundation for a successful work environment in the NCAA Division I clinical setting potentially can center on the management style of the supervisor, especially one who promotes teamwork among his or her staff members. Although a family-friendly work environment is necessary for work-life balance, each member of the athletic training staff must have personal strategies in place to fully achieve a balance.
Fulfillment of work-life balance from the organizational perspective: a case study.
Mazerolle, Stephanie M; Goodman, Ashley
2013-01-01
Researchers studying work-life balance have examined policy development and implementation to create a family-friendly work environment from an individualistic perspective rather than from a cohort of employees working under the same supervisor. To investigate what factors influence work-life balance within the National Collegiate Athletic Association (NCAA) Division I clinical setting from the perspective of an athletic training staff. Qualitative study. Web-based management system. Eight athletic trainers (5 men, 3 women; age = 38 ± 7 years) in the NCAA Division I setting. Participants responded to a series of questions by journaling their thoughts and experiences. We included data-source triangulation, multiple-analyst triangulation, and peer review to establish data credibility. We analyzed the data via a grounded theory approach. Three themes emerged from the data. Family-oriented and supportive work environment was described as a workplace that fosters and encourages work-life balance through professionally and personally shared goals. Nonwork outlets included activities, such as exercise and personal hobbies, that provide time away from the role of the athletic trainer. Individualistic strategies reflected that although the athletic training staff must work together and support one another, each staff member must have his or her own personal strategies to manage personal and professional responsibilities. The foundation for a successful work environment in the NCAA Division I clinical setting potentially can center on the management style of the supervisor, especially one who promotes teamwork among his or her staff members. Although a family-friendly work environment is necessary for work-life balance, each member of the athletic training staff must have personal strategies in place to fully achieve a balance.
Using stochastic cell division and death to probe minimal units of cellular replication
NASA Astrophysics Data System (ADS)
Chib, Savita; Das, Suman; Venkatesan, Soumya; Sai Narain Seshasayee, Aswin; Thattai, Mukund
2018-03-01
The invariant cell initiation mass measured in bacterial growth experiments has been interpreted as a minimal unit of cellular replication. Here we argue that the existence of such minimal units induces a coupling between the rates of stochastic cell division and death. To probe this coupling we tracked live and dead cells in Escherichia coli populations treated with a ribosome-targeting antibiotic. We find that the growth exponent from macroscopic cell growth or decay measurements can be represented as the difference of microscopic first-order cell division and death rates. The boundary between cell growth and decay, at which the number of live cells remains constant over time, occurs at the minimal inhibitory concentration (MIC) of the antibiotic. This state appears macroscopically static but is microscopically dynamic: division and death rates exactly cancel at MIC but each is remarkably high, reaching 60% of the antibiotic-free division rate. A stochastic model of cells as collections of minimal replicating units we term ‘widgets’ reproduces both steady-state and transient features of our experiments. Sub-cellular fluctuations of widget numbers stochastically drive each new daughter cell to one of two alternate fates, division or death. First-order division or death rates emerge as eigenvalues of a stationary Markov process, and can be expressed in terms of the widget’s molecular properties. High division and death rates at MIC arise due to low mean and high relative fluctuations of widget number. Isolating cells at the threshold of irreversible death might allow molecular characterization of this minimal replication unit.
Guan, J-Z; Wang, J-J; Cheng, Z-H; Liu, Y; Li, Z-Y
2012-01-17
Houttuynia cordata (Saururaceae) is a leaf vegetable and a medicinal herb througout much of Asia. Cytomixis and meiotic abnormalities during microsporogenesis were found in two populations of H. cordata with different ploidy levels (2n = 38, 96). Cytomixis occurred in pollen mother cells during meiosis at high frequencies and with variable degrees of chromatin/chromosome transfer. Meiotic abnormalities, such as chromosome laggards, asymmetric segregation and polyads, also prevailed in pollen mother cells at metaphase of the first division and later stages. They were caused by cytomixis and resulted in very low pollen viability and male sterility. Pollen mother cells from the population with 2n = 38 showed only simultaneous cytokinesis, but most pollen mother cells from the population with 2n = 96 showed successive cytokinesis; a minority underwent simultaneous cytokinesis. Cytomixis and irregular meiotic divisions appear to be the origin of the intraspecific polyploidy in this species, which has large variations in chromosome numbers.
Health physics division annual progress report for period ending June 30, 1977
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1978-07-01
This annual progress report follows, as in the past, the organizational structure of the Health Physics Division. Each part is a report of work done by a section of the division: Assessment and Technology Section (Part I), headed by H.W. Dickson; Biological and Radiation Physics Section (Part II), H.A. Wright; Chemical Physics and Spectroscopy Section (Part III), W.R. Garrett; Emergency Technology Section (Part IV), C.V. Chester, Medical Physics and Internal Dosimetry Section (Part V), K.E. Cowser; and the Analytic Dosimetry and Education Group (Part VI), J.E. Turner.
Juckett, D A
1987-03-01
A model is presented which proposes a specific cause-and-effect relationship between a limited cell division potential and the maximum lifespan of humans and other mammals. It is based on the clonal succession hypothesis of Kay which states that continually replicating cell beds (e.g. bone marrow, intestinal crypts, epidermis) could be composed of cells with short, well-defined division potentials. In this model, the cells of these beds are proposed to exist in an ordered hierarchy which establishes a specific sequence for cell divisions throughout the organism's lifespan. The depletion of division potential at all hierarchical levels leads to a loss of bed function and sets an intrinsic limit to species longevity. A specific hierarchy for cell proliferation is defined which allows the calculation of time to bed depletion and, ultimately, to organism mortality. The model allows the existence of a small number (n) of critical cell beds within the organism and defines organism death as the inability of any one of these beds to produce cells. The model is consistent with all major observations related to cellular and organismic aging. In particular, it links the PDLs (population doubling limit) observed for various species to their mean lifespan; it explains the slow decline in PDL as a function of age of the donor; it establishes a thermodynamically stable maximum lifespan for a disease-free population; and it can explain why tissue transplants outlive donors or hosts.
Effects of Mastery Learning Approach on Secondary School Students' Physics Achievement
ERIC Educational Resources Information Center
Wambugu, Patriciah W.; Changeiywo, Johnson M.
2008-01-01
This study aimed at finding out the effects of Mastery Learning Approach (MLA) on students' achievement in Physics. The study was Quasi-experimental and Solomon Four Non-equivalent Control Group Design was used. The target population comprised of secondary school students in Kieni East Division of Nyeri District. The accessible population was Form…
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-26
..., recreational sports fields, nursing homes, schools), or disturbing the sanctity of a significant human cultural... populations with seasonal shooting closures of March 14 to June 15 show positive population growths and low to negligible risk of extirpation (Colorado Division of Wildlife 2007, p. 135). These seasonal shooting closure...
NASA Technical Reports Server (NTRS)
Hand, Zachary
2014-01-01
Over the summer I had the exciting opportunity to work for NASA at the Kennedy Space Center as a Mission Assurance Engineering intern. When I was offered a position in mission assurance for the Safety and Mission Assurance directorate's Launch Services Division, I didn't really know what I would be doing, but I knew it would be an excellent opportunity to learn and grow professionally. In this report I will provide some background information on the Launch Services Division, as well as detail my duties and accomplishments during my time as an intern. Additionally, I will relate the significance of my work experience to my current academic work and future career goals. This report contains background information on Mission Assurance Engineering, a description of my duties and accomplishments over the summer of 2014, and relates the significance of my work experience to my school work and future career goals. It is a required document for the Pathways program.
Job-related motivational factors among Malaysian employees.
Manshor, Amat Taap; Abdullah, Adilah
2002-12-01
This study identified job-related motivational factors among Malaysian employees in several telecommunication companies. Responses were obtained from 1,179 employees at all levels up to senior managers and six different functional divisions, sales and marketing, human resources, finance, technical, information, technology, and support division. All employees were asked to rate the importance of Kovach's 10 job-motivational factors. These factors were good wages, job security, opportunity for career growth in the organization, good working conditions, interesting work, company loyalty to employees, tactful discipline, full appreciation of work done, sympathetic help with personal problems, and feeling of being involved in the organization. The top five factors employees identified as motivating them in their jobs were good wages, job security, company loyalty to employees, good working conditions, and full appreciation for work done. Findings were in accordance with Kovach for U.S. employees, in which the top motivational factors were good wages and job security.
USDA-ARS?s Scientific Manuscript database
The American Chemical Society (ACS) Agricultural and Food Chemistry Division (AGFD) and the ACS International Chemical Sciences Chapter in Thailand (ICSCT) worked together to stage the “1st Joint ACS AGFD - ACS ICSCT Symposium on Agricultural and Food Chemistry,” which was held in Bangkok, Thailand ...
ERIC Educational Resources Information Center
Quimby, Freeman H.; Chapman, Cynthia B.
This document was compiled by the Specialist, Life Sciences, Science Policy Research Division and the Analyst, Biological Sciences, Science Policy Research Division of the Library of Congress in response to a request of the Senate Select Committee on Nutrition and Human Needs. Submitted under the general title, "A Compilation of Key Papers for Use…
U.S. Army Reserve 88th Readiness Division Finds Big Savings
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
Fact sheet features lighting work done for the U.S. Army Reserve 88th Readiness Division, which was recognized in two 2017 Interior Lighting Campaign exemplary recognition categories. The troffer lighting upgrade projects at the two recognized sites are expected to save more than 246,000 kWh annually or roughly enough electricity to run 23 homes for a year.
USDA-ARS?s Scientific Manuscript database
This work is devoted to review the new scientific divisions that emerged in agrophysics in the last 10-15 years. Among them are the following: 1) application of Adaptive Neuro-Fuzzy Inference System (ANFIS), 2) development and application of fuzzy indicator modeling, 3) agrophysical and physic-tech...
Laboratory Measurements of Cometary Photochemical Phenomena.
1981-12-04
PROGFIAM ELEMENT.PROJECT TASK Laser .Chemistry Division AREA & WORK UNIT NUMaZRS Department of Chemistry - Howard University NR.051-733 Wash’ ngtQn, D. C...William M. Jackson Laser Chemistry Division Department of Chemistry Howard University .Washington, D. C. 20059 / Published by Jet Propulsion Laboratory...MEASUREMENTS OF COMETARY PHOTOCHEMICAL PHENOMENA William M. Jackson Howard University Washington, DC 20059 Abstract Laboratory experiments are described
ERIC Educational Resources Information Center
Dunbar, Mary Elizabeth
This research was to determine the relationship between New York State Cooperative Extension 4-H Division Leaders' propensity toward delegation of work responsibility and (1) their degree of involvement in the performance of leader identification and selection tasks, (2) assignment of major responsibility for these tasks, and (3) other selected…
Accumulation of neutral mutations in growing cell colonies with competition.
Sorace, Ron; Komarova, Natalia L
2012-12-07
Neutral mutations play an important role in many biological processes including cancer initiation and progression, the generation of drug resistance in bacterial and viral diseases as well as cancers, and the development of organs in multicellular organisms. In this paper we study how neutral mutants are accumulated in nonlinearly growing colonies of cells subject to growth constraints such as crowding or lack of resources. We investigate different types of growth control which range from "division-controlled" to "death-controlled" growth (and various mixtures of both). In division-controlled growth, the burden of handling overcrowding lies with the process of cell-divisions, the divisions slow down as the carrying capacity is approached. In death-controlled growth, it is death rate that increases to slow down expansion. We show that division-controlled growth minimizes the number of accumulated mutations, and death-controlled growth corresponds to the maximum number of mutants. We check that these results hold in both deterministic and stochastic settings. We further develop a general (deterministic) theory of neutral mutations and achieve an analytical understanding of the mutant accumulation in colonies of a given size in the absence of back-mutations. The long-term dynamics of mutants in the presence of back-mutations is also addressed. In particular, with equal forward- and back-mutation rates, if division-controlled and a death-controlled types are competing for space and nutrients, cells obeying division-controlled growth will dominate the population. Copyright © 2012 Elsevier Ltd. All rights reserved.
Tulina, Natalia M; Chen, Wen-Feng; Chen, Jung Hsuan; Sowcik, Mallory; Sehgal, Amita
2014-02-25
Adult stem cells maintain tissue integrity and function by renewing cellular content of the organism through regulated mitotic divisions. Previous studies showed that stem cell activity is affected by local, systemic, and environmental cues. Here, we explore a role of environmental day-night cycles in modulating cell cycle progression in populations of adult stem cells. Using a classic stem cell system, the Drosophila spermatogonial stem cell niche, we reveal daily rhythms in division frequencies of germ-line and somatic stem cells that act cooperatively to produce male gametes. We also examine whether behavioral sleep-wake cycles, which are driven by the environmental day-night cycles, regulate stem cell function. We find that flies lacking the sleep-promoting factor Sleepless, which maintains normal sleep in Drosophila, have increased germ-line stem cell (GSC) division rates, and this effect is mediated, in part, through a GABAergic signaling pathway. We suggest that alterations in sleep can influence the daily dynamics of GSC divisions.
Kinetics of cell division in epidermal maintenance
NASA Astrophysics Data System (ADS)
Klein, Allon M.; Doupé, David P.; Jones, Phillip H.; Simons, Benjamin D.
2007-08-01
The rules governing cell division and differentiation are central to understanding the mechanisms of development, aging, and cancer. By utilizing inducible genetic labeling, recent studies have shown that the clonal population in transgenic mouse epidermis can be tracked in vivo. Drawing on these results, we explain how clonal fate data may be used to infer the rules of cell division and differentiation underlying the maintenance of adult murine tail-skin. We show that the rates of cell division and differentiation may be evaluated by considering the long-time and short-time clone fate data, and that the data is consistent with cells dividing independently rather than synchronously. Motivated by these findings, we consider a mechanism for cancer onset based closely on the model for normal adult skin. By analyzing the expected changes to clonal fate in cancer emerging from a simple two-stage mutation, we propose that clonal fate data may provide a novel method for studying the earliest stages of the disease.
Structural Engineering: Overview
NASA Technical Reports Server (NTRS)
Castro, Edgar
2011-01-01
This slide presentation presents the work of the Structural Engineering Division of the Engineering Directorate. The work includes: providing technical expertise and leadership for the development, evaluation, and operation of structural, mechanical, and thermal spaceflight systems.
The erythrocyte acid phosphatase isoenzyme distribution among the negroid population of Rhodesia.
Kobus, H J; Fowler, J C
1979-01-01
The value of the erythrocyte acid phosphatase isoenzyme system as a method for blood typing in forensic science in Rhodesia has been evaluated. Three hundred and three blood samples from negroid people were examined. The high incidence of the B phenotype (72%) results in a poor division of the population using this system. The R allele which has been found in other negroid peoples also occurs in the Rhodesian population.
29 CFR 785.48 - Use of time clocks.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR INTERPRETATION NOT DIRECTLY RELATED TO REGULATIONS HOURS WORKED Recording Working Time § 785.48 Use of time... actually work. For enforcement purposes this practice of computing working time will be accepted, provided...
78 FR 68501 - International Standards on the Transport of Dangerous Goods
Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-14
... include: Review of Working papers Working Group updates Regulatory Cooperation Council (RCC) Update... sessions, can be found on the United Nations Economic Commission for Europe (UNECE) Transport Division Web... its decisions on Working Papers. The Working Papers for the 26th session of the UNSCEGHS are located...
Time-Lapse Cinemicrographic Studies of X-Irradiated HeLa S3 Cells
Hurwitz, Camilla; Tolmach, L. J.
1969-01-01
Analysis of time-lapse cinemicrographs of X-irradiated HeLa S3 cells has shown that the incidence of cell fusion was increased from 0.9% (following 1267 divisions) in control cells to an average of 22% (following 655 divisions) in cells irradiated with 500 rad doses of 220 kv X-rays. The incidence depended on the stage of the generation cycle at which the parent cells were irradiated. It was nearly constant in the first three postirradiation generations. Fusion occurred at all stages of the generation cycle, but preferentially during the first 20%. Cells undergoing fusion progressed more slowly through the generation cycle and had a higher probability of disintegrating than did irradiated cells that did not fuse. The occurrence of fusion was clonally distributed in the population. It took place only between sister (or closely related) cells. Protoplasmic bridges were often visible between sister cells prior to fusion. Giant cells arose only as a result of fusion. The incidence of multipolar divisions, though higher than in unirradiated cells, was only 5.5% in cultures irradiated with 500 rads. Fusion occurred following 85% of the multipolar divisions and was often followed by a multipolar division. ImagesFigure 1 PMID:5807221
The second missing link: Bible nursing in 19th century London.
Denny, E
1997-12-01
The London Bible and Domestic Female Mission was founded in 1857 by Ellen Ranyard. A nursing mission was added in 1868. The structure and work of the mission can be used to exemplify three strategies utilized in Victorian philanthropy. First, the use of working class women in the maintenance of social order, secondly the utilization of the middle class household to exemplify relations between the social classes, and thirdly the creation of districts in an attempt to recreate a 'golden age' of rural communities. Ranyard created a women's mission to women. As such it did not display the gender division of labour apparent in much health and caring work, but a hierarchical division of labour based on social class is evident.
New insights into mechanisms of stem cell daughter fate determination in regenerative tissues.
Sada, Aiko; Tumbar, Tudorita
2013-01-01
Stem cells can self-renew and differentiate over extended periods of time. Understanding how stem cells acquire their fates is a central question in stem cell biology. Early work in Drosophila germ line and neuroblast showed that fate choice is achieved by strict asymmetric divisions that can generate each time one stem and one differentiated cell. More recent work suggests that during homeostasis, some stem cells can divide symmetrically to generate two differentiated cells or two identical stem cells to compensate for stem cell loss that occurred by direct differentiation or apoptosis. The interplay of all these factors ensures constant tissue regeneration and the maintenance of stem cell pool size. This interplay can be modeled as a population-deterministic dynamics that, at least in some systems, may be described as stochastic behavior. Here, we overview recent progress made on the characterization of stem cell dynamics in regenerative tissues. Copyright © 2013 Elsevier Inc. All rights reserved.
Building research and evaluation capacity in population health: the NSW Health approach.
Edwards, Barry; Stickney, Beth; Milat, Andrew; Campbell, Danielle; Thackway, Sarah
2016-02-01
Issue addressed An organisational culture that values and uses research and evaluation (R&E) evidence to inform policy and practice is fundamental to improving health outcomes. The 2016 NSW Government Program Evaluation Guidelines recommend investment in training and development to improve evaluation capacity. The purpose of this paper is to outline the approaches taken by the NSW Ministry of Health to develop R&E capacity and assess these against existing models of practice. Method The Ministry of Health's Centre for Epidemiology and Evidence (CEE) takes an evidence-based approach to building R&E capacity in population health. Strategies are informed by: the NSW Population Health Research Strategy, R&E communities of practice across the Ministry and health Pillar agencies and a review of the published evidence on evaluation capacity building (ECB). An internal survey is conducted biennially to monitor research activity within the Ministry's Population and Public Health Division. One representative from each of the six centres that make up the Division coordinates completion of the survey by relevant staff members for their centre. Results The review identified several ECB success factors including: implementing a tailored multifaceted approach; an organisational commitment to R&E; and offering experiential training and ongoing technical support to the workforce. The survey of research activity found that the Division funded a mix of research assets, research funding schemes, research centres and commissioned R&E projects. CEE provides technical advice and support services for staff involved in R&E and in 2015, 22 program evaluations were supported. R&E capacity building also includes a series of guides to assist policy makers, practitioners and researchers to commission, undertake and use policy-relevant R&E. Staff training includes workshops on critical appraisal, program logic and evaluation methods. From January 2013 to June 2014 divisional staff published 84 peer-reviewed papers and one book chapter. Conclusion A strategic approach to R&E capacity building compares favourably with organisational dimensions of ECB and has facilitated the generation of high quality population health R&E in NSW. So what? An evidence-based multistrategy approach to population health R&E can result in substantial contributions to the population-health evidence base.
An assessment of burnout in graduate assistant certified athletic trainers.
Mazerolle, Stephanie M; Monsma, Eva; Dixon, Colin; Mensch, James
2012-01-01
Graduate assistant athletic trainers (GAATs) must balance the demands of clinical care and the academic load of graduate-level students. To examine burnout among GAATs with clinical assistantships at National Collegiate Athletic Association (NCAA) Division I institutions and to identify the personal and situational variables that are related to burnout. Cross-sectional study. Division I universities offering graduate assistantship programs. Two hundred one GAATs enrolled at NCAA Division I universities with graduate assistantship positions. The Athletic Training Burnout Inventory, which assesses stress and burnout among ATs through 4 constructs: emotional exhaustion and depersonalization, administrative responsibility, time commitment, and organizational support. The 6-point Likert scale is anchored by 1 (never true) and 6 (always true). The GAATs who traveled with athletic teams (4.051 ± 0.895) and those who provided classroom instruction (4.333 ± 1.16) reported higher levels of stress due to time commitment than those who did not travel (3.713 ± 1.22) or teach (3.923 ± 0.929). We also found a difference in administrative responsibility across clinical settings (F(6,194) = 3.507, P = .003). The results showed that GAATs in NCAA Division I clinical settings (44.55 ± 13.17 hours) worked more hours than those in NCAA Division III clinical settings (33.69 ± 12.07 hours) and those in high school settings (30.51 ± 9.934 hours). Graduate assistant ATs are at risk for burnout because of the time necessary to complete their clinical and academic responsibilities and their additional administrative responsibilities. Graduate assistants who work in the Division I clinical setting are at greater risk for burnout than those in the secondary school setting because of the large number of hours required.
Santana-Cabrera, J; Velasco-Vázquez, J; Rodríguez-Rodríguez, A
2015-04-01
The aim of this paper is to investigate the relationship between entheseal changes and sexual division of labor in the pre-Hispanic population of Gran Canaria Island (Spain). Ethnohistorical records from the period of contact between Europeans and the Canarian indigenous population provide rich information about the different activities performed by men and women. For this purpose, entheseal changes in a sample of 138 individuals (82 males and 56 females) buried in ten pre-Hispanic cemeteries (11th and 15th centuries cal. CE) were analyzed. Forty-one entheses located in the clavicle, humerus, ulna and radius were analyzed (fibrous and fibro-cartilaginous attachment sites). Entheses were graded using a visual and descriptive standard which summarized the entheseal changes. This method interprets the changes as a sign of robustness on a scale from low to high development and includes enthesopathies. The intra- and inter-observer error of this method was minimal. Sex differences in the degree of robustness, bilateral asymmetry, sexual dimorphism and principal components analyses were tested in this sample. The results indicate significant variance in the entheseal robustness between males and females. They also suggest the impact of certain biomechanical chains (pronosupination, shoulder rotation, etc.) in entheseal changes. These results contribute to an interdisciplinary approach to the study of the sexual division of labor in the pre-Hispanic society of Gran Canaria. Copyright © 2015 Elsevier GmbH. All rights reserved.
The US Environmental Protection Agency's (EPA) National Health and Environmental Effects Research Laboratory (NHEERL) in the Environmental Public Health Division (EPHD) is currently engaged in research aimed at developing a measure that estimates overall environmental quality at the county level for the United States. This work is being conducted as an effort to learn more about how various environmental factors simultaneously contribute to health disparities in low-income and minority populations, and to better estimate the total environmental and social context to which humans are exposed. This dataset contains the finalized Environmental Quality Index (EQI), and an index for each of the associated domains (air, water, land, built environment, and sociodemographic environment). Indices are at the county level for all counties in the United States.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-21
... Science Subcommittee; Supporting Research and Technology Working Group; Meeting AGENCY: National... announces a meeting of the Supporting Research and Technology Working Group of the Planetary Science... INFORMATION CONTACT: Dr. Michael New, Planetary Science Division, National Aeronautics and Space...
River Ice Data Instrumentation
1997-06-01
transmission and storage of data. Fi- nally, recommendations are made for further work in the field of ice data collection. North Atlantic \\N...Missouri River Division (MRD) Kansas City Omaha MRK MRO 7 32 20 11 North Atlantic Division (NAD) Baltimore New York Norfolk Philadelphia... Western 1 r~ T T Ice Thickness U Water Temperature < > Air Temperature i ► Discharge < | Water Stage < [ Ice Areal Coverage a Ice
ERIC Educational Resources Information Center
Michigan State Univ., East Lansing.
This agreement, entered into July 1, 1974, is between the Board of Trustees of Michigan State University and Lodge 141 of the Fraternal Order of Police, Michigan State University Division. It is the intent and purpose of this agreement to assure sound and mutually beneficial working and economic relationships between the parties, to provide an…
Circuit-switch architecture for a 30/20-GHz FDMA/TDM geostationary satellite communications network
NASA Technical Reports Server (NTRS)
Ivancic, William D.
1992-01-01
A circuit switching architecture is described for a 30/20 GHz frequency division, multiple access uplink/time division multiplexed downlink (FDMA/TDM) geostationary satellite communications network. Critical subsystems and problem areas are identified and addressed. Work was concentrated primarily on the space segment; however, the ground segment was considered concurrently to ensure cost efficiency and realistic operational constraints.
A Fundamental Study of the Electromagnetic Properties of Advanced Composite Materials
1978-07-01
MKDC), Space and Missile Systems Organization (SAMSO). Aeronautical System Division (ASD), Electronic Systems Division ( ESD ), Air Force Avionics...discussions, the work reported involved only one fiber type--Thornel T300 as used in Narmco 5208 pre-preg tapes . Individual graphite fibers have radii... teflon coated tweezers to separate individual fibers from the bundle. Microscopic observation and a steady hand during this procedure improved the
ERIC Educational Resources Information Center
International Federation of Library Associations, The Hague (Netherlands).
The 10 papers in this collection were presented at an open forum and meetings of three sections within the Division of Bibliographic Control: (1) "Review of the Work of the Section on Cataloguing 1989/1990" (Nancy R. John and Inger Cathrine Spangen); (2) "Report from the Section on Classification and Indexing" (Dorothy…
Real-Time Population Health Detector
2004-11-01
military and civilian populations. General Dynamics (then Veridian Systems Division), in cooperation with Stanford University, won a competitive DARPA...via the sequence of one-step ahead forecast errors from the Kalman recursions: 1| −−= tttt Hye µ The log-likelihood then follows by treating the... parking in the transient parking structure. Norfolk Area Military Treatment Facility Patient Files GDAIS received historic CHCS data from all
Imported Talent: Foreign Immigration and the New England Labor Market
ERIC Educational Resources Information Center
Sum, Andrew; Trubs'kyy, Mykhaylo; Fogg, Neeta P.
2003-01-01
The impacts of foreign immigration on population and labor force growth during the 1990s varied widely across U.S. geographic regions, divisions and states. New England was far more dependent than nearly all other regions on the new wave of foreign immigrants to achieve its population growth and labor force growth during the past decade. In fact,…
Demography, Identity and the 2016 Presidential Election
ERIC Educational Resources Information Center
Davidson, Fiona M.; Sours, Tad; Moll, Rebecca Luebker
2016-01-01
Demography is the study of human population statistics. The United States Census Bureau has measured the demographics of the U.S. population since 1790. Why? The main purpose was for division of representatives of the people in government and for taxes. As time has gone on, it gives us a better picture of who we are as a nation and how to better…
29 CFR 553.224 - “Work period” defined.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 29 Labor 3 2010-07-01 2010-07-01 false âWork periodâ defined. 553.224 Section 553.224 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS APPLICATION... Enforcement Employees of Public Agencies Tour of Duty and Compensable Hours of Work Rules § 553.224 “Work...
Code of Federal Regulations, 2010 CFR
2010-07-01
... to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR... Permittedâ to Work § 785.11 General. Work not requested but suffered or permitted is work time. For example, an employee may voluntarily continue to work at the end of the shift. He may be a pieceworker, he may...
One Step Forward, Two Steps Back? Work Experience, Equal Opportunities and TVEI.
ERIC Educational Resources Information Center
Heath, Sue
1995-01-01
A case study of work experience provided in a British project committed to gender equality shows that the nature of work experience--its alliance with labor market needs--makes it virtually impossible to meet equal opportunity objectives. Work experience tends to reinforce existing gender divisions in the labor market. (SK)
29 CFR 530.202 - Piece rates-work measurement.
Code of Federal Regulations, 2010 CFR
2010-07-01
... different types of items produced using stop watch time studies or other work measurement methods... Hour Division. (b) The fact that an employer bases piece rates on work measurements which indicate that... 29 Labor 3 2010-07-01 2010-07-01 false Piece rates-work measurement. 530.202 Section 530.202 Labor...
7 CFR 654.14 - Duration of sponsor(s)' responsibility.
Code of Federal Regulations, 2010 CFR
2010-01-01
... performed by force account, division of work, or performance of work methods, the sponsor(s)' O&M responsibilities begin on the date the work or portion thereof is completed as determined by NRCS, except for completed work located on Federal lands which are subject to special-use permits. The O&M agreement shall...
Elliott, Kayla R; Harmatz, Jerold S; Zhao, Yanli; Greenblatt, David J
2016-05-01
Collegiate football programs encourage athletes to pursue high body weights. To examine position-dependent trends over time in body size characteristics among football players in the National Collegiate Athletic Association Division III New England Small College Athletic Conference (NESCAC) from 1956 to 2014 and to compare the observed absolute and relative changes with those in age-matched male population controls. Descriptive laboratory study. Medical school affiliated with a NESCAC institution. Football team rosters from the 10-member NESCAC schools, available as public documents, were analyzed along with body size data from general population males aged 20 to 29 years from the National Health and Nutrition Examination Survey (NHANES). Body weight, height, and calculated body mass index were evaluated using analysis of variance, linear regression, and nonlinear regression to determine the distribution features of size variables and changes associated with time (year), school, and position. Among NESCAC linemen, absolute and relative changes over time in body weight and body mass index exceeded corresponding changes in the NHANES population controls. New England Small College Athletic Conference offensive linemen body weights increased by 37.5% from 1956 to 2014 (192 to 264 lb [86.4 to 118.8 kg]), compared with a 12% increase (164 to 184 lb [73.8 to 82.8 kg]) since 1961 in the NHANES population controls. Body mass index changed in parallel with body weight and exceeded 35 kg/m(2) in more than 30% of contemporary NESCAC offensive linemen. Among skill players in the NESCAC group, time-related changes in body size characteristics generally paralleled those in the NHANES controls. High body weight and body mass indices were evident in offensive linemen, even among those in Division III football programs with no athletic scholarships. These characteristics may be associated with adverse cardiovascular and metabolic outcomes. We need approaches to encourage risk modification in the postfootball lifestyles of these individuals.
Division of Labor, Bet Hedging, and the Evolution of Mixed Biofilm Investment Strategies.
Lowery, Nick Vallespir; McNally, Luke; Ratcliff, William C; Brown, Sam P
2017-08-08
Bacterial cells, like many other organisms, face a tradeoff between longevity and fecundity. Planktonic cells are fast growing and fragile, while biofilm cells are often slower growing but stress resistant. Here we ask why bacterial lineages invest simultaneously in both fast- and slow-growing types. We develop a population dynamic model of lineage expansion across a patchy environment and find that mixed investment is favored across a broad range of environmental conditions, even when transmission is entirely via biofilm cells. This mixed strategy is favored because of a division of labor where exponentially dividing planktonic cells can act as an engine for the production of future biofilm cells, which grow more slowly. We use experimental evolution to test our predictions and show that phenotypic heterogeneity is persistent even under selection for purely planktonic or purely biofilm transmission. Furthermore, simulations suggest that maintenance of a biofilm subpopulation serves as a cost-effective hedge against environmental uncertainty, which is also consistent with our experimental findings. IMPORTANCE Cell types specialized for survival have been observed and described within clonal bacterial populations for decades, but why are these specialists continually produced under benign conditions when such investment comes at a high reproductive cost? Conversely, when survival becomes an imperative, does it ever benefit the population to maintain a pool of rapidly growing but vulnerable planktonic cells? Using a combination of mathematical modeling, simulations, and experiments, we find that mixed investment strategies are favored over a broad range of environmental conditions and rely on a division of labor between cell types, where reproductive specialists amplify survival specialists, which can be transmitted through the environment with a limited mortality rate. We also show that survival specialists benefit rapidly growing populations by serving as a hedge against unpredictable changes in the environment. These results help to clarify the general evolutionary and ecological forces that can generate and maintain diverse subtypes within clonal bacterial populations. Copyright © 2017 Lowery et al.
Metals and Ceramics Division progress report for period ending June 30, 1984
DOE Office of Scientific and Technical Information (OSTI.GOV)
Brogden, I.
1984-09-01
This progress report covers the research and development activities of the Metals and Ceramics Division from January 1, 1983, through June 30, 1984. The format of the report follows the organizational structure of the division. Short summaries of technical work in progress in the various experimental groups are presented in six parts. Chapter 1 deals with the research and development activities of the Engineering Materials Section, Chapter 2 with the Processing Science and Technology Section, Chapter 3 with the Materials Science Section, Chapter 4 with Project Activities, Chapter 5 with Specialized Research Facilities and Equipment, and Chapter 6 with Miscellaneousmore » Activities.« less
Powell, J.W.
1891-01-01
The work of the United States Irrigation Survey during the second year has been carried oil under the appropriation of $250,000 made March 2, 1889, by the force organized and equipped during the previous year. This is pursuant to the purposes outlined in the first annual report, which explains the origin, purpose, and plan of the Survey, publishes the instructions to the chiefs of the larger divisions, and gives the report of the topographic division to the end of the first fiscal year, and the reports of the hydrographic and engineering divisions during the greater part of the calendar year 1889.
SYED, I.; DALY, T.; ARMSTRONG, P.; LOWNDES, R.; CHADOIN, M.; NAIDOO, V.
2016-01-01
Background According to the Canadian Health Care Association (1), there are 2,577 long-term care (“LTC”) facilities across Canada, with the largest proportion (33.4%) located in Ontario. Most studies focus on residents’ health, with less attention paid to the health and safety experiences of staff. Given that the work performed in Ontario LTC facilities is very gendered, increasingly racialized, task-oriented, and with strict divisions of labour, this paper explores in what ways some of these factors impact workers’ experiences of health and safety. Objectives The study objectives included the following research question: How are work hierarchies and task orientation experienced by staff? Design and Setting This paper draws on data from rapid team-based ethnographies of the shifting division of labour in LTC due to use of informal carers in six non-profit LTC facilities located in Toronto, Ontario. Methods Our method involved conducting observations and key informant interviews (N=167) with registered nurses, registered practical nurses, personal support workers, dietary aides, recreation therapists, families, privately paid companions, students, and volunteers. Interviews were audio-recorded, transcribed verbatim, and thematically analyzed. For observations, researchers were paired and covered shifts between 7 a.m. and 11 p.m., as well as into the late night over six days, at each of the six sites. Detailed ethnographic field notes were written during and immediately following observational fieldwork. Results Our results indicate that employee stress is linked to the experiences of care work hierarchies, task orientation, and strict divisions of labour between and among various staff designations. Conclusion Findings from this project confirm and extend current research that demonstrates there are challenging working conditions in LTC, which can result in occupational health and safety problems, as well as stress for individual workers. PMID:28066839
Updating the transportation plans in Virginia's small urban areas.
DOT National Transportation Integrated Search
1987-01-01
The Transportation Planning Division (TPD) of the Virginia Department of Transportation is responsible for developing transportation plans for areas in the state having a population greater than 3,500. Although transportation forecasting procedures f...
29 CFR 785.31 - Special situations.
Code of Federal Regulations, 2010 CFR
2010-07-01
... employee at such courses outside of working hours would not be hours worked even if they are directly... Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR INTERPRETATION NOT DIRECTLY RELATED TO REGULATIONS HOURS WORKED Application of Principles Lectures, Meetings and...
Task-switching costs promote the evolution of division of labor and shifts in individuality
Goldsby, Heather J.; Dornhaus, Anna; Kerr, Benjamin; Ofria, Charles
2012-01-01
From microbes to humans, the success of many organisms is achieved by dividing tasks among specialized group members. The evolution of such division of labor strategies is an important aspect of the major transitions in evolution. As such, identifying specific evolutionary pressures that give rise to group-level division of labor has become a topic of major interest among biologists. To overcome the challenges associated with studying this topic in natural systems, we use actively evolving populations of digital organisms, which provide a unique perspective on the de novo evolution of division of labor in an open-ended system. We provide experimental results that address a fundamental question regarding these selective pressures: Does the ability to improve group efficiency through the reduction of task-switching costs promote the evolution of division of labor? Our results demonstrate that as task-switching costs rise, groups increasingly evolve division of labor strategies. We analyze the mechanisms by which organisms coordinate their roles and discover strategies with striking biological parallels, including communication, spatial patterning, and task-partitioning behaviors. In many cases, under high task-switching costs, individuals cease to be able to perform tasks in isolation, instead requiring the context of other group members. The simultaneous loss of functionality at a lower level and emergence of new functionality at a higher level indicates that task-switching costs may drive both the evolution of division of labor and also the loss of lower-level autonomy, which are both key components of major transitions in evolution. PMID:22872867
Division of Household and Childcare Labor and Relationship Conflict Among Low-Income New Parents
Newkirk, Katie; Perry-Jenkins, Maureen; Sayer, Aline G.
2016-01-01
We examine the relationships among the division of housework and childcare labor, perceptions of its fairness for two types of family labor (housework and childcare), and parents’ relationship conflict across the transition to parenthood. Perceived fairness is examined as a mediator of the relationships between change in the division of housework and childcare and relationship conflict. Working-class, dual-earner couples (n = 108) in the U.S Northeast were interviewed at five time points from the third trimester of pregnancy and across the first year of parenthood. Research questions addressed whether change in the division of housework and childcare across the transition to parenthood predicted mothers’ and fathers’ relationship conflict, with attention to the mediating role of perceived fairness of these chores. Findings for housework indicated that perceived fairness was related to relationship conflict for mothers and fathers, such that when spouses perceived the change in the division of household tasks to be unfair to either partner, they reported more conflict, However, fairness did not significantly mediate relations between changes in division of household tasks and later relationship conflict. For childcare, fairness mediated relations between mothers’ violated expectations concerning the division of childcare and later conflict such that mothers reported less conflict when they perceived the division of childcare as less unfair to themselves; there was no relationship for fathers. Findings highlight the importance of considering both childcare and household tasks independently in our models and suggest that the division of housework and childcare holds different implications for mothers’ and fathers’ assessments of relationship conflict. PMID:28348454
Jacq, Maxime; Arthaud, Christopher; Manuse, Sylvie; Mercy, Chryslène; Bellard, Laure; Peters, Katharina; Gallet, Benoit; Galindo, Jennifer; Doan, Thierry; Vollmer, Waldemar; Brun, Yves V; VanNieuwenhze, Michael S; Di Guilmi, Anne Marie; Vernet, Thierry; Grangeasse, Christophe; Morlot, Cecile
2018-05-15
Bacterial division is intimately linked to synthesis and remodeling of the peptidoglycan, a cage-like polymer that surrounds the bacterial cell, providing shape and mechanical resistance. The bacterial division machinery, which is scaffolded by the cytoskeleton protein FtsZ, includes proteins with enzymatic, structural or regulatory functions. These proteins establish a complex network of transient functional and/or physical interactions which preserve cell shape and cell integrity. Cell wall hydrolases required for peptidoglycan remodeling are major contributors to this mechanism. Consistent with this, their deletion or depletion often results in morphological and/or division defects. However, the exact function of most of them remains elusive. In this work, we show that the putative lysozyme activity of the cell wall hydrolase Pmp23 is important for proper morphology and cell division in the opportunistic human pathogen Streptococcus pneumoniae. Our data indicate that active Pmp23 is required for proper localization of the Z-ring and the FtsZ-positioning protein MapZ. In addition, Pmp23 localizes to the division site and interacts directly with the essential peptidoglycan synthase PBP2x. Altogether, our data reveal a new regulatory function for peptidoglycan hydrolases.
Report of work done in the division of chemistry and physics, mainly during the fiscal year 1889-90
Clarke, Frank Wigglesworth
1891-01-01
This bulletin, like the bulletins issued in previous years and numbered 9, 27, 42, 55, 60, and 64, contains a partial record of work completed in the chemical and physical laboratories of the Survey Turing one tiscAl year. It represents, however, only a portion of the whole work done, for various investigations, begun during the year 1859—'90, are still unfinished; many analyses are reserved for publication in other reports; and certain of the larger researches, notably the physical studies of Dr. Barns, will appear in independent form as separate bulletins. In the annual reports of the Director of the Survey a tolerably complete summary of the work done in the Division of Chemistry and Physics is always given, and such summaries, taken in connection with these bulletins, convey.a fair idea of the amount of ground actually covered.
The stem cell division theory of cancer.
López-Lázaro, Miguel
2018-03-01
All cancer registries constantly show striking differences in cancer incidence by age and among tissues. For example, lung cancer is diagnosed hundreds of times more often at age 70 than at age 20, and lung cancer in nonsmokers occurs thousands of times more frequently than heart cancer in smokers. An analysis of these differences using basic concepts in cell biology indicates that cancer is the end-result of the accumulation of cell divisions in stem cells. In other words, the main determinant of carcinogenesis is the number of cell divisions that the DNA of a stem cell has accumulated in any type of cell from the zygote. Cell division, process by which a cell copies and separates its cellular components to finally split into two cells, is necessary to produce the large number of cells required for living. However, cell division can lead to a variety of cancer-promoting errors, such as mutations and epigenetic mistakes occurring during DNA replication, chromosome aberrations arising during mitosis, errors in the distribution of cell-fate determinants between the daughter cells, and failures to restore physical interactions with other tissue components. Some of these errors are spontaneous, others are promoted by endogenous DNA damage occurring during quiescence, and others are influenced by pathological and environmental factors. The cell divisions required for carcinogenesis are primarily caused by multiple local and systemic physiological signals rather than by errors in the DNA of the cells. As carcinogenesis progresses, the accumulation of DNA errors promotes cell division and eventually triggers cell division under permissive extracellular environments. The accumulation of cell divisions in stem cells drives not only the accumulation of the DNA alterations required for carcinogenesis, but also the formation and growth of the abnormal cell populations that characterize the disease. This model of carcinogenesis provides a new framework for understanding the disease and has important implications for cancer prevention and therapy. Copyright © 2018 Elsevier B.V. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Larry G. Hoffman; Kenneth Alvar; Thomas Buhl
1999-06-01
This progress report presents the results of 10 projects funded ($504K) in FY98 by the Technology Development, Evaluation, and Application (TDEA) Committee of the Environment, Safety, and Health Division. Nine projects are new for this year; two projects were completed in their third and final TDEA-funded year. As a result of their TDEA-funded projects, investigators have published 19 papers in professional journals, proceedings, or Los Alamos reports and presented their work at professional meetings. Supplemental funds and in-kind contributions, such as staff time, instrument use, and work space were also provided to the TDEA-funded projects by organizations external to ESHmore » Division. Products generated from the projects funded in FY98 included a new extremity dosimeter that replaced the previously used finger-ring dosimeters, a light and easy-to-use detector to measure energy deposited by neutron interactions, and a device that will allow workers to determine the severity of a hazard.« less
Promise and problems in relating cellular senescence in vitro to aging in vivo.
Rubin, Harry
2002-01-01
According to the 'Hayflick limit', human fetal fibroblasts have a uniform, limited replicative lifespan of about 50 population doublings in cell culture. This concept was extrapolated to diverse cells in the body. It seemed to decrease with the age of the cell donor and, as a form of cell senescence, was thought to underlie the aging process. More discriminating analysis, however, showed that the fibroblasts decayed in a stochastic manner from the time of their explantation, at a rate that increased with the number of population doublings in culture. There was no consistent relation to the age of the donor. Despite the contradictory evidence, the original version of the Hayflick limit retained its general acceptance. Cell senescence was attributed to the absence of telomerase in the fibroblasts, which resulted in shortening of telomeres at each division until they fell below a critical length needed for further division. However, it is well established that stem cells in renewing tissues undergo many more than 50 divisions in a lifetime, without apparent senescence. Contrary to early findings of no telomerase in most tissues, their stem cells retain telomerase and presumably telomere length despite many divisions in vivo. Massive accumulation of lipofuscin granules occurs under stress in long term crowded cultures, but the granules dissipate on subculture or neoplastic transformation. The overall results indicate a critical disjunction between cell senescence in vitro and aging in vivo. By contrast, cell culture has been useful in showing a need for telomere capping in maintaining cell stability and viability. It may also provide information about the biochemical mechanism of lipofuscin production.
A computational perspective on autism
Rosenberg, Ari; Patterson, Jaclyn Sky; Angelaki, Dora E.
2015-01-01
Autism is a neurodevelopmental disorder that manifests as a heterogeneous set of social, cognitive, motor, and perceptual symptoms. This system-wide pervasiveness suggests that, rather than narrowly impacting individual systems such as affection or vision, autism may broadly alter neural computation. Here, we propose that alterations in nonlinear, canonical computations occurring throughout the brain may underlie the behavioral characteristics of autism. One such computation, called divisive normalization, balances a neuron’s net excitation with inhibition reflecting the overall activity of the neuronal population. Through neural network simulations, we investigate how alterations in divisive normalization may give rise to autism symptomatology. Our findings show that a reduction in the amount of inhibition that occurs through divisive normalization can account for perceptual consequences of autism, consistent with the hypothesis of an increased ratio of neural excitation to inhibition (E/I) in the disorder. These results thus establish a bridge between an E/I imbalance and behavioral data on autism that is currently absent. Interestingly, our findings implicate the context-dependent, neuronal milieu as a key factor in autism symptomatology, with autism reflecting a less “social” neuronal population. Through a broader discussion of perceptual data, we further examine how altered divisive normalization may contribute to a wide array of the disorder’s behavioral consequences. These analyses show how a computational framework can provide insights into the neural basis of autism and facilitate the generation of falsifiable hypotheses. A computational perspective on autism may help resolve debates within the field and aid in identifying physiological pathways to target in the treatment of the disorder. PMID:26170299
Velo‐Suárez, Lourdes; Ralston, David K.; Fox, Sophia E.; Sehein, Taylor R.; Shalapyonok, Alexi; Sosik, Heidi M.; Olson, Robert J.; Anderson, Donald M.
2015-01-01
Abstract Transitions between life cycle stages by the harmful dinoflagellate Alexandrium fundyense are critical for the initiation and termination of its blooms. To quantify these transitions in a single population, an Imaging FlowCytobot (IFCB), was deployed in Salt Pond (Eastham, Massachusetts), a small, tidally flushed kettle pond that hosts near annual, localized A. fundyense blooms. Machine‐based image classifiers differentiating A. fundyense life cycle stages were developed and results were compared to manually corrected IFCB samples, manual microscopy‐based estimates of A. fundyense abundance, previously published data describing prevalence of the parasite Amoebophrya, and a continuous culture of A. fundyense infected with Amoebophrya. In Salt Pond, a development phase of sustained vegetative division lasted approximately 3 weeks and was followed by a rapid and near complete conversion to small, gamete cells. The gametic period (∼3 d) coincided with a spike in the frequency of fusing gametes (up to 5% of A. fundyense images) and was followed by a zygotic phase (∼4 d) during which cell sizes returned to their normal range but cell division and diel vertical migration ceased. Cell division during bloom development was strongly phased, enabling estimation of daily rates of division, which were more than twice those predicted from batch cultures grown at similar temperatures in replete medium. Data from the Salt Pond deployment provide the first continuous record of an A. fundyense population through its complete bloom cycle and demonstrate growth and sexual induction rates much higher than are typically observed in culture. PMID:27667858
Biological consequences and advantages of asymmetric bacterial growth.
Kysela, David T; Brown, Pamela J B; Huang, Kerwyn Casey; Brun, Yves V
2013-01-01
Asymmetries in cell growth and division occur in eukaryotes and prokaryotes alike. Even seemingly simple and morphologically symmetric cell division processes belie inherent underlying asymmetries in the composition of the resulting daughter cells. We consider the types of asymmetry that arise in various bacterial cell growth and division processes, which include both conditionally activated mechanisms and constitutive, hardwired aspects of bacterial life histories. Although asymmetry disposes some cells to the deleterious effects of aging, it may also benefit populations by efficiently purging accumulated damage and rejuvenating newborn cells. Asymmetries may also generate phenotypic variation required for successful exploitation of variable environments, even when extrinsic changes outpace the capacity of cells to sense and respond to challenges. We propose specific experimental approaches to further develop our understanding of the prevalence and the ultimate importance of asymmetric bacterial growth.
C46 `ASTRONOMY Education and Development': a Peculiar Commission
NASA Astrophysics Data System (ADS)
de Greve, Jean-Pierre; García, Beatriz; Gerbaldi, Michèle; Ferlet, Roger; Guinan, Edward; Hearnshaw, John; Jones, Barrie; Marschall, Laurence; Miley, George; Pasachoff, Jay; Ros, Rosa; Stavinschi, Magda; Torres-Peimbert, Silvia
2016-04-01
C46 was a Commission of the Executive Committee of the IAU under Division XII (Union-Wide Activities), then after 2012 under Division C (Education, Outreach, and Heritage). It was the only commission dealing exclusively with astronomy education; a previous Commission 38 (Exchange of Astronomers), which allocated travel grants to astronomers who needed them, and a Working Group on the Worldwide Development of Astronomy, have been absorbed by Commission 46.
2016-10-01
BRIEFING CHARTS) D. Zeppettella Structures Technology Branch Aerospace Vehicles Division Steve Bucca and Thomas Gage BerrieHill Research...R. WIPPERMAN, Chief Program Manager Structures Technology Branch Structures Technology Branch Aerospace Vehicles Division Aerospace Vehicles...Corporation) 5d. PROJECT NUMBER 4920 5e. TASK NUMBER 5f. WORK UNIT NUMBER Q06A 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 8. PERFORMING
1992-08-01
recommend that representatives of the WES Concrete Technology Division be onsite during the placement and postplacement phases to offer technical...written before field placement. PREFACE The work described in this report is part of an ongoing research effort accomplished in the Concrete Technology ... Division (CTD), Structures Laboratory (SL), U.S. Army Engineer Waterways Experiment Station (WES), under Interagency Agreement from the Department of
ERIC Educational Resources Information Center
2003
The Media Ethics Division of the proceedings contains the following 10 papers: "Punctuation and Epistemic Honesty: Do Photos Need What Words Have?" (Scott Fosdick and Shahira Fahmy); "A Bellwether in Media Accountability: The Work of the New York 'World's' Bureau of Accuracy and Fair Play" (Neil Nemeth); "Eight Arguments…
[Working together, how and for which care?
Acker, Françoise; Perraut Soliveres, Anne
The division and specialisation of the work of doctors and nurses is heightening the tensions in their professional relations. The increased interdependency of actions requires more collaboration between health professionals. 'Working together' can be facilitated by a reflected work organisation style, a shared vision of care and work between nursing managers and heads of department. Copyright © 2017 Elsevier Masson SAS. All rights reserved.
ERIC Educational Resources Information Center
Boumans, Nicolle P. G.; de Jong, Ad H. J.; Janssen, Sara M.
2011-01-01
This study investigated the influence of age on the relationship between work characteristics and workers' work motivation and job satisfaction. In total, 1036 workers of a Dutch division of a multinational organization participated. Data were collected by a digital questionnaire. Two interaction terms in the regression on work motivation were…
ERIC Educational Resources Information Center
Fejes, Andreas; Haake, Ulrika
2013-01-01
This paper aims to problematise how gender is being done--1. through occupational choices in two occupations that are traditionally gender divided, elderly care and police work, and 2. through the division of work assignments in police work. Interviews with care workers and police officers are analysed using a "doing gender" perspective, a…
48 CFR 22.403-4 - Department of Labor regulations.
Code of Federal Regulations, 2011 CFR
2011-10-01
... under the Davis-Bacon Act, Contract Work Hours and Safety Standards Act, Copeland (Anti-Kickback) Act... Division, or administrative law judges under the Davis-Bacon Act, Contract Work Hours and Safety Standards... of weekly payroll records; (3) Part 5, relating to enforcement of the Davis-Bacon Act, Contract Work...
Divisions of Labour: Activity Theory, Multi-Professional Working and Intervention Research
ERIC Educational Resources Information Center
Warmington, Paul
2011-01-01
This article draws upon, but also critiques, activity theory by combining analysis of how an activity theory derived research intervention attempted to address both everyday work practices and organisational power relationships among children's services professionals. It offers two case studies of developmental work research (DWR) interventions in…
29 CFR 825.106 - Joint employer coverage.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS THE FAMILY... coverage. (a) Where two or more businesses exercise some control over the work or working conditions of the... leave who is working for a secondary employer is considered employed by the secondary employer, and must...
Hayflick, L
1979-07-01
Cultured normal human and animal cells are predestinued to undergo irreversible functional decrements that mimick age changes in the whole organism. When normal human embryonic fibroblasts are cultured in vitro, 50 +/- 10 population doublings occur. This maximum potential is diminished in cells derived from older donors and appears to be inversely proportional to their age. The 50 population doubling limit can account for all cells produced during a lifetime. The limitation on doubling potential of cultured normal cells is also expressed in vivo when serial transplants are made. There may be a direct correlation between the mean maximum life spans of several species and the population doubling potential of their cultured cells. A plethora of functional decrements occur in cultured normal cells as they approach their maximum division capability. Many of these decrements are similar to those occurring in intact animals as they age. We have concluded that these functional decrements expressed in vitro, rather than cessation of cell division, are the essential contributors to age changes in intact animals. Thus, the study of events leading to functional losses in cultured normal cells may provide useful insights into the biology of aging.
Who, How, and Where: Special Education's Issues in Perpetuity.
ERIC Educational Resources Information Center
Bateman, Barbara D.
1994-01-01
Issues that are central to special education and appear destined to remain so are discussed, including professional divisions among special educators and between special and regular educators, the population to be served, individualization, and placement. (JDD)
CELL POPULATION KINETICS OF EXCISED ROOTS OF PISUM SATIVUM
Van't Hof, Jack
1965-01-01
The cell population kinetics of excised, cultured pea roots was studied with the use of tritiated thymidine and colchicine to determine (1) the influence of excision, (2) the influence of sucrose concentration, (3) the average mitotic cycle duration, and (4) the duration of mitosis and the G 1, S, and G 2 periods of interphase.1 The results indicate that the process of excision causes a drop in the frequency of mitotic figures when performed either at the beginning of the culture period or after 100 hours in culture. This initial decrease in frequency of cell division is independent of sucrose concentration, but the subsequent rise in frequency of division, after 12 hours in culture, is dependent upon sucrose concentration. Two per cent sucrose maintains the shortest mitotic cycle duration. The use of colchicine indicated an average cycle duration of 20 hours, whereas the use of tritiated thymidine produced an average cycle duration of 17 hours. PMID:5857253
Ito, Kyoko; Turcotte, Raphaël; Cui, Jinhua; Zimmerman, Samuel E; Pinho, Sandra; Mizoguchi, Toshihide; Arai, Fumio; Runnels, Judith M; Alt, Clemens; Teruya-Feldstein, Julie; Mar, Jessica C; Singh, Rajat; Suda, Toshio; Lin, Charles P; Frenette, Paul S; Ito, Keisuke
2016-12-02
A single hematopoietic stem cell (HSC) is capable of reconstituting hematopoiesis and maintaining homeostasis by balancing self-renewal and cell differentiation. The mechanisms of HSC division balance, however, are not yet defined. Here we demonstrate, by characterizing at the single-cell level a purified and minimally heterogeneous murine Tie2 + HSC population, that these top hierarchical HSCs preferentially undergo symmetric divisions. The induction of mitophagy, a quality control process in mitochondria, plays an essential role in self-renewing expansion of Tie2 + HSCs. Activation of the PPAR (peroxisome proliferator-activated receptor)-fatty acid oxidation pathway promotes expansion of Tie2 + HSCs through enhanced Parkin recruitment in mitochondria. These metabolic pathways are conserved in human TIE2 + HSCs. Our data thus identify mitophagy as a key mechanism of HSC expansion and suggest potential methods of cell-fate manipulation through metabolic pathways. Copyright © 2016, American Association for the Advancement of Science.
Ito, Kyoko; Turcotte, Raphaël; Cui, Jinhua; Zimmerman, Samuel E.; Pinho, Sandra; Mizoguchi, Toshihide; Arai, Fumio; Runnels, Judith M.; Alt, Clemens; Teruya-Feldstein, Julie; Mar, Jessica C.; Singh, Rajat; Suda, Toshio; Lin, Charles P.; Frenette, Paul S.; Ito, Keisuke
2016-01-01
A single hematopoietic stem cell (HSC) is capable of reconstituting hematopoiesis and maintaining homeostasis by balancing self-renewal and cell differentiation. The mechanisms of HSC division balance, however, are not yet defined. Here we demonstrate, by characterizing at the single-cell level a purified and minimally heterogeneous murine Tie2+ HSC population, that these top hierarchical HSCs preferentially undergo symmetric divisions. The induction of mitophagy, a quality control process in mitochondria, plays an essential role in self-renewing expansion of Tie2+ HSCs. Activation of the PPAR (peroxisome proliferator–activated receptor)–fatty acid oxidation pathway promotes expansion of Tie2+ HSCs through enhanced Parkin recruitment in mitochondria. These metabolic pathways are conserved in human TIE2+ HSCs. Our data thus identify mitophagy as a key mechanism of HSC expansion and suggest potential methods of cell-fate manipulation through metabolic pathways. PMID:27738012
Counterinsurgency in Iraq (2003-2006)
2008-01-01
population in the preceding four years had contributed significantly to the subse- quent increase in insurgency and sectarian violence . In the security...excesses, a pullback of Shi’a mili- tias from anti-Sunni violence and confrontation with coalition forces, a decrease in externally supplied...the divisions between the Sunni, Shi’a, and Kurdish elements of the population. Nevertheless, the reduced level of violence as of early 2008 was an
Men's Provider-Role Attitudes: Implications for Household Work and Marital Satisfaction.
ERIC Educational Resources Information Center
Perry-Jenkins, Maureen; Crouter, Ann C.
1990-01-01
Examined spousal division of work inside and outside family home in couples (N=43) and cognitions men attach to their work and family roles. Found men's provider-role attitudes were related to their family work involvement. Found congruence of role beliefs and role behavior within home related to higher levels of marital satisfaction for men.…
Children's Time Use: Labor Divisions and Schooling in Indonesia
ERIC Educational Resources Information Center
Hsin, Amy
2007-01-01
Data from the Worker and Iron Status Evaluation are used to examine gendered patterns in children's time in market and nonmarket work, schooling, and leisure in Indonesia (N = 2,929). Boys spend more time in market work; girls spend more time in nonmarket work. Work responsibilities increase with age as well as gender differentials in children's…
29 CFR 778.115 - Employees working at two or more rates.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 29 Labor 3 2010-07-01 2010-07-01 false Employees working at two or more rates. 778.115 Section 778.115 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR... Employees working at two or more rates. Where an employee in a single workweek works at two or more...
WILLOW CREEK RECLAMATION PROJECT
Working in cooperation with the EPA, Colorado Division of Minerals and Geology, and others, the Willow Creek Reclamation Committee (WCRC) will investigate the sources and character of water entering the mine workings on the Amethyst vein near the town of Creede, Colorado. Activi...
Cell Division Induces and Switches Coherent Angular Motion within Bounded Cellular Collectives.
Siedlik, Michael J; Manivannan, Sriram; Kevrekidis, Ioannis G; Nelson, Celeste M
2017-06-06
Collective cell migration underlies many biological processes, including embryonic development, wound healing, and cancer progression. In the embryo, cells have been observed to move collectively in vortices using a mode of collective migration known as coherent angular motion (CAM). To determine how CAM arises within a population and changes over time, here, we study the motion of mammary epithelial cells within engineered monolayers, in which the cells move collectively about a central axis in the tissue. Using quantitative image analysis, we find that CAM is significantly reduced when mitosis is suppressed. Particle-based simulations recreate the observed trends, suggesting that cell divisions drive the robust emergence of CAM and facilitate switches in the direction of collective rotation. Our simulations predict that the location of a dividing cell, rather than the orientation of the division axis, facilitates the onset of this motion. These predictions agree with experimental observations, thereby providing, to our knowledge, new insight into how cell divisions influence CAM within a tissue. Overall, these findings highlight the dynamic nature of CAM and suggest that regulating cell division is crucial for tuning emergent collective migratory behaviors, such as vortical motions observed in vivo. Copyright © 2017 Biophysical Society. Published by Elsevier Inc. All rights reserved.
Molecular Programs Underlying Asymmetric Stem Cell Division and Their Disruption in Malignancy.
Mukherjee, Subhas; Brat, Daniel J
2017-01-01
Asymmetric division of stem cells is a highly conserved and tightly regulated process by which a single stem cell produces two unequal daughter cells. One retains its stem cell identity while the other becomes specialized through a differentiation program and loses stem cell properties. Coordinating these events requires control over numerous intra- and extracellular biological processes and signaling networks. In the initial stages, critical events include the compartmentalization of fate determining proteins within the mother cell and their subsequent passage to the appropriate daughter cell in order to direct their destiny. Disturbance of these events results in an altered dynamic of self-renewing and differentiation within the cell population, which is highly relevant to the growth and progression of cancer. Other critical events include proper asymmetric spindle assembly, extrinsic regulation through micro-environmental cues, and non-canonical signaling networks that impact cell division and fate determination. In this review, we discuss mechanisms that maintain the delicate balance of asymmetric cell division in normal tissues and describe the current understanding how some of these mechanisms are deregulated in cancer.
Girel, Simon; Crauste, Fabien
2018-06-01
Unequal partitioning of the molecular content at cell division has been shown to be a source of heterogeneity in a cell population. We propose to model this phenomenon with the help of a scalar, nonlinear impulsive differential equation (IDE). To study the effect of molecular partitioning at cell division on the effector/memory cell-fate decision in a CD8 T-cell lineage, we study an IDE describing the concentration of the protein Tbet in a CD8 T-cell, where impulses are associated to cell division. We discuss how the degree of asymmetry of molecular partitioning can affect the process of cell differentiation and the phenotypical heterogeneity of a cell population. We show that a moderate degree of asymmetry is necessary and sufficient to observe irreversible differentiation. We consider, in a second part, a general autonomous IDE with fixed times of impulse and a specific form of impulse function. We establish properties of the solutions of that equation, most of them obtained under the hypothesis that impulses occur periodically. In particular, we show how to investigate the existence of periodic solutions and their stability by studying the flow of an autonomous differential equation. Then we apply those properties to prove the results presented in the first part.
High-throughput monitoring of major cell functions by means of lensfree video microscopy
Kesavan, S. Vinjimore; Momey, F.; Cioni, O.; David-Watine, B.; Dubrulle, N.; Shorte, S.; Sulpice, E.; Freida, D.; Chalmond, B.; Dinten, J. M.; Gidrol, X.; Allier, C.
2014-01-01
Quantification of basic cell functions is a preliminary step to understand complex cellular mechanisms, for e.g., to test compatibility of biomaterials, to assess the effectiveness of drugs and siRNAs, and to control cell behavior. However, commonly used quantification methods are label-dependent, and end-point assays. As an alternative, using our lensfree video microscopy platform to perform high-throughput real-time monitoring of cell culture, we introduce specifically devised metrics that are capable of non-invasive quantification of cell functions such as cell-substrate adhesion, cell spreading, cell division, cell division orientation and cell death. Unlike existing methods, our platform and associated metrics embrace entire population of thousands of cells whilst monitoring the fate of every single cell within the population. This results in a high content description of cell functions that typically contains 25,000 – 900,000 measurements per experiment depending on cell density and period of observation. As proof of concept, we monitored cell-substrate adhesion and spreading kinetics of human Mesenchymal Stem Cells (hMSCs) and primary human fibroblasts, we determined the cell division orientation of hMSCs, and we observed the effect of transfection of siCellDeath (siRNA known to induce cell death) on hMSCs and human Osteo Sarcoma (U2OS) Cells. PMID:25096726
Meeting Report: Pancreatic Cancer Chemoprevention Translational Workshop
Miller, Mark Steven; Allen, Peter; Brentnall, Teresa; Goggins, Michael; Hruban, Ralph H.; Petersen, Gloria M.; Rao, Chinthalapally V.; Whitcomb, David C.; Brand, Randall E.; Chari, Suresh; Klein, Alison; Lubman, David; Rhim, Andrew; Simeone, Diane M.; Wolpin, Brian; Umar, Asad; Srivastava, Sudhir; Steele, Vernon E.; Ann Rinaudo, Jo
2016-01-01
Pancreatic cancer is the 4th leading cause of cancer related deaths in the US with a 5 year survival rate of <10%. The Division of Cancer Prevention of the NCI sponsored the Pancreatic Cancer Chemoprevention Translational Workshop on September 10–11th 2015. The goal of the workshop was to obtain information regarding the current state of the science and future scientific areas that should be prioritized for pancreatic cancer prevention research, including early detection and intervention for high-risk precancerous lesions. The workshop addressed the molecular/genetic landscape of pancreatic cancer and precursor lesions; high risk populations and criteria to identify a high risk population for potential chemoprevention trials; identification of chemopreventative/immuopreventative agents; and use of potential biomarkers and imaging for assessing short term efficacy of a preventative agent. The field of chemoprevention for pancreatic cancer is emerging and this workshop was organized to begin to address these important issues and promote multi-institutional efforts in this area. The meeting participants recommended the development of an NCI working group to coordinate efforts, provide a framework, and identify opportunities for chemoprevention of pancreatic cancer. PMID:27518363
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ward, David L.
The authors report on their progress from April 1998 through March 1999 on determining the effects of mitigative measures on productivity of white sturgeon populations in the Columbia River downstream from McNary Dam, and on determining the status and habitat requirements of white sturgeon populations in the Columbia and Snake rivers upstream from McNary Dam. The study is a cooperative effort by the Oregon Department of Fish and Wildlife (ODFW; Report A), Washington Department of Fish and Wildlife (WDFW; Report B), U.S. Geological Survey Biological Resources Division (USGS; Report C), U.S. Fish and Wildlife Service (USFWS; Report D), Columbia Rivermore » Inter-Tribal Fish Commission (CRITFC; Report E), and the University of Idaho (UI; Report F). This is a multi-year study with many objectives requiring more than one year to complete. Therefore, findings from a given year may be part of more significant findings yet to be reported. Highlights of results of our work from April 1998 through March 1999 are given.« less
Coleman, D A
2002-01-01
This paper considers international migration in the context of population ageing. In many Western countries, the search for appropriate responses to manage future population ageing and population decline has directed attention to international migration. It seems reasonable to believe that international migrants, mostly of young working age, can supply population deficits created by low birth rates, protect European society and economy from the economic costs of elderly dependency, and provide a workforce to care for the elderly. Particular prominence has been given to this option through the publicity attendant on a report from the UN Population Division in 2000 on 'replacement migration', which has been widely reported and widely misunderstood. Although immigration can prevent population decline, it is already well known that it can only prevent population ageing at unprecedented, unsustainable and increasing levels of inflow, which would generate rapid population growth and eventually displace the original population from its majority position. This paper reviews these arguments in the context of the causes and inevitability of population ageing, with examples mostly based on UK data. It discusses various options available in response to population ageing through workforce, productivity, pensions reform and other means. It concludes that there can be no 'solution' to population ageing, which is to a considerable degree unavoidable. However, if the demographic regime of the United Kingdom continues to be relatively benign, future population ageing can be managed with tolerable inconvenience without recourse to increased immigration for 'demographic' purposes. At present (2001), net immigration to the United Kingdom is already running at record levels and is now the main engine behind UK population and household growth. By itself, population stabilization, or even mild reduction, is probably to be welcomed in the United Kingdom, although the issue has attracted little attention since the 1970s. PMID:12028794
NASA Technical Reports Server (NTRS)
Jordan, Kevin
1999-01-01
The following contains the final report on the activities related to the Cooperative Agreement between the human factors research group at NASA Ames Research Center and the Psychology Department at San Jose State University. The participating NASA Ames division has been, as the organization has changed, the Aerospace Human Factors Research Division (ASHFRD and Code FL), the Flight Management and Human Factors Research Division (Code AF), and the Human Factors Research and Technology Division (Code IH). The inclusive dates for the report are November 1, 1984 to January 31, 1999. Throughout the years, approximately 170 persons worked on the cooperative agreements in one capacity or another. The Cooperative Agreement provided for research personnel to collaborate with senior scientists in ongoing NASA ARC research. Finally, many post-MA/MS and post-doctoral personnel contributed to the projects. It is worth noting that 10 former cooperative agreement personnel were hired into civil service positions directly from the agreements.
The Division of Household Labor: Longitudinal Changes and Within-Couple Variation.
Lam, Chun Bun; McHale, Susan M; Crouter, Ann C
2012-10-01
This study examined how the division of household labor changed as a function of marital duration and whether within-couple variation in spouses' relative power and availability were linked to within-couple variation in the division of labor. On 4 occasions over 7 years, 188 stably married couples reported on their housework activities using daily diaries. Multilevel models revealed that wives' portions of household responsibilities declined over time, and that changes in spouses' relative income and work hours were linked to changes in housework allocation. Wives with husbands who perceived greater marital control, on average, did proportionally more housework, and for couples with husbands who had highly autonomous jobs, changes in spouses' relative psychological job involvement were linked to changes in housework allocation. Findings highlight the importance of understanding household division of labor as a lifespan phenomenon, the distinction between within- versus between-couple associations, and the multidimensional nature of power and availability.
HLA-DRB1 alleles in four Amerindian populations from Argentina and Paraguay
2009-01-01
The major histocompatibility complex (MHC) is one of the biological systems of major polymorphisms. The study of HLA class II variability has allowed the identification of several alleles that are characteristic to Amerindian populations, and it is an excellent tool to define the relations and biological affinities among them. In this work, we analyzed the allelic distribution of the HLA-DRB1 class II locus in four Amerindian populations: Mapuche (n = 34) and Tehuelche (n = 23) from the Patagonian region of Argentina, and Wichi SV (n = 24) and Lengua (n = 17) from the Argentinean and Paraguayan Chaco regions, respectively. In all of these groups, relatively high frequencies of Amerindian HLA-DRB1 alleles were observed (DRB1*0403, DRB1*0407, DRB1*0411, DRB1*0417, DRB1*0802, DRB1*0901, DRB1*1402, DRB1*1406 and DRB1*1602). However, we also detected the presence of non-Amerindian variants in Mapuche (35%) and Tehuelche (22%). We compared our data with those obtained in six indigenous groups of the Argentinean Chaco region and in a sample from Buenos Aires City. The genetic distance dendrogram showed a clear-cut division between the Patagonian and Chaco populations, which formed two different clusters. In spite of their linguistic differences, it can be inferred that the biological affinities observed are in concordance with the geographic distributions and interethnic relations established among the groups studied. PMID:21637670
NASA Astrophysics Data System (ADS)
Perrone, D.; Duncan, L. L.; Jacobi, J. H.; Hornberger, G.
2012-12-01
Water resources are vital to sustaining ecosystem services, energy and food supplies, and industrial processes. Competition for water resources is likely to intensify as the population increases, economy grows, and land develops. Drought events intensify water scarcity, and recent events in many countries, including the United States (US), Great Britain, and Sri Lanka, highlight how important it is to provide meaningful context to water planners and managers. Palmer's drought indices - Z Index, Palmer Drought Severity Index (PDSI), and Palmer Hydrological Drought Index (PHDI) - are widely used and accepted by scientists and policy makers in the US to understand drought and manage water resources. Drought index values at the climate division scale are available, but a transparent calculation tool at multiple spatial and temporal scales is not readily available. Moreover, a close look at the development of the indices reveals a number of subjective calculation methods and regionally biased factors. For researchers studying areas with overlapping climate divisions, performing international research, or working with limited, site-specific data, the ability to control and modify calculations is desired. This research presents a transparent tool for calculating Palmer's drought indices. We use the Apalachicola-Chattahoochee-Flint (ACF) River Basin, located in the southeastern US, as our case study to explore and evaluate the sensitivity of Palmer's indices to temperature and precipitation anomalies, calibration periods, and other index components. The ACF has suffered two major droughts (2007 and 2012) in the past five years and supports multiple demand-side sectors - agriculture in Georgia, public and recreational supply for the Atlanta metropolitan area, hydroelectric power in Alabama, tri-state navigation, and ecosystem services. We show how the PDSI varies in response to changes in precipitation, calibration period, and a number of other variables. The aim of the work is to make this easily used tool available to help professionals who work toward facilitating water management and reducing water conflicts in the future.
DOE Office of Scientific and Technical Information (OSTI.GOV)
L.G. Hoffman; K. Alvar; T. Buhl
2002-05-01
This progress report presents the results of 11 projects funded ($500K) in FY01 by the Technology Development, Evaluation, and Application (TDEA) Committee of the Environment, Safety, and Health Division (ESH). Five projects fit into the Health Physics discipline, 5 projects are environmental science and one is industrial hygiene/safety. As a result of their TDEA-funded projects, investigators have published sixteen papers in professional journals, proceedings, or Los Alamos reports and presented their work at professional meetings. Supplement funds and in-kind contributions, such as staff time, instrument use, and workspace, were also provided to TDEA-funded projects by organizations external to ESH Divisions.
Mathis, Roland; Ackermann, Martin
2016-01-01
Most bacteria live in ever-changing environments where periods of stress are common. One fundamental question is whether individual bacterial cells have an increased tolerance to stress if they recently have been exposed to lower levels of the same stressor. To address this question, we worked with the bacterium Caulobacter crescentus and asked whether exposure to a moderate concentration of sodium chloride would affect survival during later exposure to a higher concentration. We found that the effects measured at the population level depended in a surprising and complex way on the time interval between the two exposure events: The effect of the first exposure on survival of the second exposure was positive for some time intervals but negative for others. We hypothesized that the complex pattern of history dependence at the population level was a consequence of the responses of individual cells to sodium chloride that we observed: (i) exposure to moderate concentrations of sodium chloride caused delays in cell division and led to cell-cycle synchronization, and (ii) whether a bacterium would survive subsequent exposure to higher concentrations was dependent on the cell-cycle state. Using computational modeling, we demonstrated that indeed the combination of these two effects could explain the complex patterns of history dependence observed at the population level. Our insight into how the behavior of single cells scales up to processes at the population level provides a perspective on how organisms operate in dynamic environments with fluctuating stress exposure. PMID:26960998
Global Energy: Supply, Demand, Consequences, Opportunities
Majumdar, Arun
2017-12-09
July 29, 2008 Berkeley Lab lecture: Arun Majumdar, Director of the Environmental Energy Technologies Division, discusses current and future projections of economic growth, population, and global energy demand and supply, and explores the implications of these trends for the environment.
DCEG scientists discuss researching cancer causes and training future researchers
Watch scientists in the NCI Division of Cancer Epidemiology and Genetics discuss research into the causes of cancer at the population level. Topics include genome-wide association studies, HPV genomics, Li-Fraumeni syndrome, and training future scientists.
ERIC Educational Resources Information Center
International Federation of Library Associations, The Hague (Netherlands).
The 23 papers in this collection include papers on special libraries and miscellaneous contributed papers: (1) "Networking Potentialities and Limitations--Special Library Networks in Socialist Countries--An Overview, and the Main Ways of Perestroika in the Work of Scientific and Technical Libraries at the Present Stage" (D. Schmidmaier…
1982-03-10
ADDRESS 10. PROGRAM ELEMENT. PROJECT. TASK Division of Medicine , Walter Reed Army Institute o7 AREA & WORK UNIT NUMBERS Research, Endocrine Metabolic...Service, Walter Reed C Army Medical Center, Washington, D.C. 20012 I. CONTROLLING OFFICE NAME AND ADDRESS 12. REPORT DATE Division of Medicine Walter...THIS PAGE (When Date Entered) * .1 Unclassified SECURITY CLASSIFICATION OF THIS PAGIE(When "ea Entmuod)- antithyroid drug therapy. Estrogens produced a
Optical time division multiplexer on silicon chip.
Aboketaf, Abdelsalam A; Elshaari, Ali W; Preble, Stefan F
2010-06-21
In this work, we experimentally demonstrate a novel broadband optical time division multiplexer (OTDM) on a silicon chip. The fabricated devices generate 20 Gb/s and 40 Gb/s signals starting from a 5 Gb/s input signal. The proposed design has a small footprint of 1mm x 1mm. The system is inherently broadband with a bandwidth of over 100nm making it suitable for high-speed optical networks on chip.
2016-06-10
proficiency in their core competencies. 15. SUBJECT TERMS Fires, Fire Support, DIVARTY, FAB , Combined Arms Maneuver, DOTMLPF 16. SECURITY...FAA Functional Area Analysis FAB Field Artillery Brigade FER Final Exercise Report FFA HQ Force Field Artillery Headquarters FM Field Manual FNA...function. This provided me the opportunity to work with several Division Artillerys (DIVARTYs) and Field Artillery Brigades ( FABs ). During this time
NASA Technical Reports Server (NTRS)
Gardner, J. E.; Dixon, S. C.
1985-01-01
The loads and aeroelasticity divisions research accomplishments are presented. The work under each branch or technical area, described in terms of highlights of accomplishments during the past year and highlights of plans for the current year as they relate to 5 year plans for each technical area. This information will be useful in program coordination with other government organizations and industry in areas of mutual interest.
7 CFR 11.14 - Filing of appeals and computation of time.
Code of Federal Regulations, 2010 CFR
2010-01-01
... other day on which the Division is not open for the transaction of business during normal working hours, the time for filing will be extended to the close of business on the next working day. (c) The time...
Aid to private transportation providers : a working paper.
DOT National Transportation Integrated Search
1979-01-01
This working paper was prepared for the Public Transportation Division. Within the three-week period in which it was prepared, little more than a cursory examination could be made of the number of private providers operating in Virginia; however, the...
Workdays, Workhours, and Work Schedules: Evidence for the United States and Germany.
ERIC Educational Resources Information Center
Hamermesh, Daniel S.
This book studies work in the United States and Germany from two new viewpoints: (1) the division of work time into hours per day and days per week (as opposed to the standard analysis of weekly hours of work); and (2) the patterns of the particular times of the day and week when people are working, a focus on instantaneous time use. Information…
Morgan Bradley_MGMT497_Final Portfolio_v2.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bradley, Morgan Lee
I work as a Year-Round Business Intern at Sandia National Laboratories. Sandia was founded during WWII under the name of Z Division as the manufacturers and assembly hands of nuclear weapons for Los Alamos National Laboratories. In the year 1948, the name Z Division was changed to Sandia National Laboratories. Sandia is a government-owned, contractoroperated facility. This means that while Sandia's work is largely government-funded Sandia is operated by a 3rd party contractor. Over the years, Sandia has been managed by different organizations, but as of May l', 2017, the current management company became the National Technology and Engineering Solutionsmore » of Sandia (NTESS) LLC.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Putnam, T.M.
This report presents the objectives, organization, policies, and essential rules and procedures that have been adopted by MP Division and that form the basis of the Health and Safety Program of the Clinton P. Anderson Meson Physics Facility (LAMPF). The facility includes the beam-delivery systems for the Los Alamos Neutron Scattering Center and the Weapons Neutron Research Facility (LANSCE/WNR). The program is designed not only to assure the health and safety of all personnel, including users, in their work at LAMPF, and of MP-Division staff in their work on the LANSCE/WNR beam lines, but also to protect the facility (buildingsmore » and equipment) and the environment. 33 refs., 18 figs., 2 tabs.« less
Varanda, Jorge; Cleveland, Todd
2014-01-01
The Companhia de Diamantes de Angola, or Diamang, mined for diamonds in colonial Angola from 1917 until independence in 1975. The enterprise's Health Services Division (SSD) was responsible for supplying mine managers with an African labour force comprised of healthy, and therefore productive, employees. In practice, though, this otherwise 'healthy' system did not always work. While SSD personnel attempted to fulfil their charge by implementing a series of screening measures, production targets and a scarcely-populated regional labour pool regularly prompted senior officials to compel the SSD to clear recruits who were otherwise unfit for mine service. Drawing upon interviews with former SSD staff and African labourers, as well as company and colonial archival sources, this article focuses on the interplay over time between the SSD, the company's production demands and these labourers.
Rossetti, Valentina; Filippini, Manuela; Svercel, Miroslav; Barbour, A D; Bagheri, Homayoun C
2011-12-07
Filamentous bacteria are the oldest and simplest known multicellular life forms. By using computer simulations and experiments that address cell division in a filamentous context, we investigate some of the ecological factors that can lead to the emergence of a multicellular life cycle in filamentous life forms. The model predicts that if cell division and death rates are dependent on the density of cells in a population, a predictable cycle between short and long filament lengths is produced. During exponential growth, there will be a predominance of multicellular filaments, while at carrying capacity, the population converges to a predominance of short filaments and single cells. Model predictions are experimentally tested and confirmed in cultures of heterotrophic and phototrophic bacterial species. Furthermore, by developing a formulation of generation time in bacterial populations, it is shown that changes in generation time can alter length distributions. The theory predicts that given the same population growth curve and fitness, species with longer generation times have longer filaments during comparable population growth phases. Characterization of the environmental dependence of morphological properties such as length, and the number of cells per filament, helps in understanding the pre-existing conditions for the evolution of developmental cycles in simple multicellular organisms. Moreover, the theoretical prediction that strains with the same fitness can exhibit different lengths at comparable growth phases has important implications. It demonstrates that differences in fitness attributed to morphology are not the sole explanation for the evolution of life cycles dominated by multicellularity.
29 CFR 785.47 - Where records show insubstantial or insignificant periods of time.
Code of Federal Regulations, 2010 CFR
2010-07-01
... scheduled working hours, which cannot as a practical administrative matter be precisely recorded for payroll... as hours worked any part, however small, of the employee's fixed or regular working time or... of time. 785.47 Section 785.47 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION...
Managerial Behaviors and Work Group Climate as Predictors of Employee Outcomes.
ERIC Educational Resources Information Center
Church, Allan H.
1995-01-01
Presents an analysis of the predictive relationships of managerial behavior and work group climate on employee outcomes; 1,428 survey responses were collected during an organizational change in the marketing and sales division of an international pharmaceuticals company. Behaviors of managers and work group members were found to be significantly…
29 CFR 785.36 - Home to work in emergency situations.
Code of Federal Regulations, 2013 CFR
2013-07-01
... is subsequently called out at night to travel a substantial distance to perform an emergency job for one of his employer's customers all time spent on such travel is working time. The Divisions are... Principles Traveltime § 785.36 Home to work in emergency situations. There may be instances when travel from...
29 CFR 785.36 - Home to work in emergency situations.
Code of Federal Regulations, 2012 CFR
2012-07-01
... is subsequently called out at night to travel a substantial distance to perform an emergency job for one of his employer's customers all time spent on such travel is working time. The Divisions are... Principles Traveltime § 785.36 Home to work in emergency situations. There may be instances when travel from...
29 CFR 785.36 - Home to work in emergency situations.
Code of Federal Regulations, 2011 CFR
2011-07-01
... is subsequently called out at night to travel a substantial distance to perform an emergency job for one of his employer's customers all time spent on such travel is working time. The Divisions are... Principles Traveltime § 785.36 Home to work in emergency situations. There may be instances when travel from...
29 CFR 785.36 - Home to work in emergency situations.
Code of Federal Regulations, 2014 CFR
2014-07-01
... is subsequently called out at night to travel a substantial distance to perform an emergency job for one of his employer's customers all time spent on such travel is working time. The Divisions are... Principles Traveltime § 785.36 Home to work in emergency situations. There may be instances when travel from...
29 CFR 785.36 - Home to work in emergency situations.
Code of Federal Regulations, 2010 CFR
2010-07-01
... is subsequently called out at night to travel a substantial distance to perform an emergency job for one of his employer's customers all time spent on such travel is working time. The Divisions are... Principles Traveltime § 785.36 Home to work in emergency situations. There may be instances when travel from...
29 CFR 793.12 - Related and incidental work.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 29 Labor 3 2011-07-01 2011-07-01 false Related and incidental work. 793.12 Section 793.12 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL... Requirements for Exemption § 793.12 Related and incidental work. An employee who is employed primarily in one...
29 CFR 779.369 - Funeral home establishments may qualify as exempt 13(a)(2) establishments.
Code of Federal Regulations, 2010 CFR
2010-07-01
...) establishments. 779.369 Section 779.369 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION..., long distance calls, newspaper notices, flowers, livery service, honoraria to participating personnel... amount of his working time to such nonexempt work. More than 20 percent of the employee's working time in...
Ayaydin, Ferhan; Kotogány, Edit; Ábrahám, Edit; Horváth, Gábor V
2017-01-01
Deepening our knowledge on the regulation of the plant cell division cycle depends on techniques that allow for the enrichment of cell populations in defined cell cycle phases. Synchronization of cell division can be achieved using different plant tissues; however, well-established cell suspension cultures provide large amount of biological sample for further analyses. Here, we describe the methodology of the establishment, propagation, and analysis of a Medicago sativa suspension culture that can be used for efficient synchronization of the cell division. A novel 5-ethynyl-2'-deoxyuridine (EdU)-based method is used for the estimation of cell fraction that enters DNA synthesis phase of the cell cycle and we also demonstrate the changes in the phosphorylation level of Medicago sativa retinoblastoma-related protein (MsRBR1) during cell cycle progression.
Asymmetric cell division during T cell development controls downstream fate
Pham, Kim; Shimoni, Raz; Charnley, Mirren; Ludford-Menting, Mandy J.; Hawkins, Edwin D.; Ramsbottom, Kelly; Oliaro, Jane; Izon, David; Ting, Stephen B.; Reynolds, Joseph; Lythe, Grant; Molina-Paris, Carmen; Melichar, Heather; Robey, Ellen; Humbert, Patrick O.; Gu, Min
2015-01-01
During mammalian T cell development, the requirement for expansion of many individual T cell clones, rather than merely expansion of the entire T cell population, suggests a possible role for asymmetric cell division (ACD). We show that ACD of developing T cells controls cell fate through differential inheritance of cell fate determinants Numb and α-Adaptin. ACD occurs specifically during the β-selection stage of T cell development, and subsequent divisions are predominantly symmetric. ACD is controlled by interaction with stromal cells and chemokine receptor signaling and uses a conserved network of polarity regulators. The disruption of polarity by deletion of the polarity regulator, Scribble, or the altered inheritance of fate determinants impacts subsequent fate decisions to influence the numbers of DN4 cells arising after the β-selection checkpoint. These findings indicate that ACD enables the thymic microenvironment to orchestrate fate decisions related to differentiation and self-renewal. PMID:26370500
A New Model for the Estimation of Cell Proliferation Dynamics Using CFSE Data
Banks, H.T.; Sutton, Karyn L.; Thompson, W. Clayton; Bocharov, Gennady; Doumic, Marie; Schenkel, Tim; Argilaguet, Jordi; Giest, Sandra; Peligero, Cristina; Meyerhans, Andreas
2011-01-01
CFSE analysis of a proliferating cell population is a popular tool for the study of cell division and division-linked changes in cell behavior. Recently [13, 43, 45], a partial differential equation (PDE) model to describe lymphocyte dynamics in a CFSE proliferation assay was proposed. We present a significant revision of this model which improves the physiological understanding of several parameters. Namely, the parameter γ used previously as a heuristic explanation for the dilution of CFSE dye by cell division is replaced with a more physical component, cellular autofluorescence. The rate at which label decays is also quantified using a Gompertz decay process. We then demonstrate a revised method of fitting the model to the commonly used histogram representation of the data. It is shown that these improvements result in a model with a strong physiological basis which is fully capable of replicating the behavior observed in the data. PMID:21889510
ERIC Educational Resources Information Center
Corrado, Marisa; Glasberg, Davita Silfen; Merenstein, Beth; Peele, Melanie R.
2000-01-01
Focuses on an exercise where students were assigned social roles based on gender, class, and race and then selected division of labor and reward structures in order to explore inequality in work and production. Offers a review of literature on the power structure of work and production and an evaluation of the exercise. (CMK)
Women "Learning to Labour" in the "Male Emporium": Exploring Gendered Work in Teacher Education
ERIC Educational Resources Information Center
Acker, Sandra; Dillabough, Jo-Anne
2007-01-01
This article reflects an interest in exposing links between women's academic work and the gender codes which organize and shape working life in the university context, both now and in the recent past, as a contribution to the sociology of women's work. Our specific focus is the gendered division of labour in teacher education in universities in…
ERIC Educational Resources Information Center
International Federation of Library Associations, The Hague (Netherlands).
Eleven of the 15 papers in this collection discuss library services for disadvantaged persons; the remaining four papers are concerned with services to multicultural populations. The papers from the Section of Libraries Serving Disadvantaged Persons appear first in this list: (1) "The Development and Future of Easy Readers for Adults in the UK"…
A Fantastic Epidemiology Journey: from China to Africa and back
Dr. Ann Hsing is a professor of medicine at Stanford University and a co-leader of the Population Sciences Program at Stanford Cancer Institute. She is also a professor in the Department of Health Research and Policy (epidemiology, by courtesy) and a faculty fellow for the Center for Innovation in Global Health. In addition, she chairs the Pacific Rim Alliance for Population Health at Stanford’s Center for Population Health Sciences. Prior to joining Stanford School of Medicine, Dr. Hsing served four years as Chief Scientific Officer at the Cancer Prevention Institute of California and 22 years as an intramural scientist (tenured senior investigator) at the Division of Cancer Epidemiology and Genetics, National Cancer Institute. Dr. Hsing received her PhD in epidemiology from the Johns Hopkins University and is widely recognized as a leading expert in the epidemiology of prostate and hepatobiliary cancer, as well as hormonal carcinogenesis and molecular epidemiology. She has authored more than 280 peer-reviewed articles and mentored over 60 pre- and post-doctoral fellows and junior scholars. At Stanford, she leads the Liver Cancer Working Group and the LDCT Screening Group, and serves as the principal investigator (PI) for wellness cohort studies in China, Taiwan, and Singapore as well as liver cancer studies in the Bay area, Taiwan, Mongolia, and Africa.
Code of Federal Regulations, 2010 CFR
2010-07-01
... outside of the employee's regular working hours; (b) Attendance is in fact voluntary; (c) The course... to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR INTERPRETATION NOT DIRECTLY RELATED TO REGULATIONS HOURS WORKED Application of Principles Lectures, Meetings and...
Trends in Community Development: Looking Back, Looking Forward.
ERIC Educational Resources Information Center
Miller, Chris; And Others
1990-01-01
Includes "Community Work in the U.K.: Reflections on the 1980s" (Miller, Bryant); "Multiplication and Divisions: Trends in Community Development in Ireland since the 1960s" (Cinneide, Walsh); "Reconstruction to Deconstruction: The Transformation of Community Work in Australia" (Meekosha; Mowbray): "Community…
Issues Related to Effects of New Maintenance Concept on AF Specialists Working in the Field
DOT National Transportation Integrated Search
1990-03-07
This working paper was prepared by the Transportation Systems Center, Operator : performance and Safety Analysis Division (DTS-45) for the Federal Aviation Ad : ministration. The paper provides initial thinking on groups of human resource issues : re...
Mazerolle, Stephanie M; Pitney, William A; Eason, Christianne M
2015-07-01
The intercollegiate setting receives much of the scholarly attention related to work-life conflict (WLC). However research has been focused on the National Collegiate Athletic Association Division I setting. Multiple factors can lead to WLC for the athletic trainer (AT), including hours, travel, and lack of flexibility in work schedules. To investigate the experiences of WLC among ATs working in the non-Division I collegiate setting and to identify factors that contribute to fulfillment of work-life balance in this setting. Qualitative study. Institutions in the National Collegiate Athletic Association Divisions II and III, the National Association of Intercollegiate Athletics, and the National Junior College Athletic Association. A total of 244 ATs (128 women, 114 men; age = 37.5 ± 13.3 years, experience = 14 ± 12 years) completed phase I. Thirteen participants (8 women, 5 men; age = 38 ± 13 years, experience = 13.1 ± 11.4 years) completed phase II. For phase I, participants completed a previously validated and reliable (Cronbach α > .90) Web-based survey measuring their levels of WLC and work-family conflict (WFC). This phase included 2 WFC scales defining family; scale 1 defined family as having a partner or spouse with or without children, and scale 2 defined family as those individuals, including parents, siblings, grandparents, and any other close relatives, involved in one's life. Phase II consisted of an interview. Qualitative data were evaluated using content analysis. Data source and multiple-analyst triangulation secured credibility. The WFC scores were 26.33 ± 7.37 for scale 1 and 20.46 ± 10.14 for scale 2, indicating a moderate level of WFC for scale 1 and a low level of WFC for scale 2. Qualitative analyses revealed that organizational dimensions, such as job demands and staffing issues, can negatively affect WLC, whereas a combination of organizational and personal dimensions can positively affect WLC. Overload continues to be a prevalent factor in negatively influencing WLC and WFC. Supervisor and peer support, personal networks, and time away from the role positively influenced work-life balance and WFC. Athletic trainers are encouraged to support one another in the workplace, especially when providing flexibility in scheduling.
Mazerolle, Stephanie M.; Pitney, William A.; Eason, Christianne M.
2015-01-01
Context The intercollegiate setting receives much of the scholarly attention related to work-life conflict (WLC). However research has been focused on the National Collegiate Athletic Association Division I setting. Multiple factors can lead to WLC for the athletic trainer (AT), including hours, travel, and lack of flexibility in work schedules. Objective To investigate the experiences of WLC among ATs working in the non-Division I collegiate setting and to identify factors that contribute to fulfillment of work-life balance in this setting. Design Qualitative study. Setting Institutions in the National Collegiate Athletic Association Divisions II and III, the National Association of Intercollegiate Athletics, and the National Junior College Athletic Association. Patients or Other Participants A total of 244 ATs (128 women, 114 men; age = 37.5 ± 13.3 years, experience = 14 ± 12 years) completed phase I. Thirteen participants (8 women, 5 men; age = 38 ± 13 years, experience = 13.1 ± 11.4 years) completed phase II. Data Collection and Analysis For phase I, participants completed a previously validated and reliable (Cronbach α > .90) Web-based survey measuring their levels of WLC and work-family conflict (WFC). This phase included 2 WFC scales defining family; scale 1 defined family as having a partner or spouse with or without children, and scale 2 defined family as those individuals, including parents, siblings, grandparents, and any other close relatives, involved in one's life. Phase II consisted of an interview. Qualitative data were evaluated using content analysis. Data source and multiple-analyst triangulation secured credibility. Results The WFC scores were 26.33 ± 7.37 for scale 1 and 20.46 ± 10.14 for scale 2, indicating a moderate level of WFC for scale 1 and a low level of WFC for scale 2. Qualitative analyses revealed that organizational dimensions, such as job demands and staffing issues, can negatively affect WLC, whereas a combination of organizational and personal dimensions can positively affect WLC. Conclusions Overload continues to be a prevalent factor in negatively influencing WLC and WFC. Supervisor and peer support, personal networks, and time away from the role positively influenced work-life balance and WFC. Athletic trainers are encouraged to support one another in the workplace, especially when providing flexibility in scheduling. PMID:25879575
An Assessment of Burnout in Graduate Assistant Certified Athletic Trainers
Mazerolle, Stephanie M.; Monsma, Eva; Dixon, Colin; Mensch, James
2012-01-01
Context: Graduate assistant athletic trainers (GAATs) must balance the demands of clinical care and the academic load of graduate-level students. Objective: To examine burnout among GAATs with clinical assistantships at National Collegiate Athletic Association (NCAA) Division I institutions and to identify the personal and situational variables that are related to burnout. Design: Cross-sectional study. Setting: Division I universities offering graduate assistantship programs. Patients or Other Participants: Two hundred one GAATs enrolled at NCAA Division I universities with graduate assistantship positions. Main Outcome Measures(s): The Athletic Training Burnout Inventory, which assesses stress and burnout among ATs through 4 constructs: emotional exhaustion and depersonalization, administrative responsibility, time commitment, and organizational support. The 6-point Likert scale is anchored by 1 (never true) and 6 (always true). Results: The GAATs who traveled with athletic teams (4.051 ± 0.895) and those who provided classroom instruction (4.333 ± 1.16) reported higher levels of stress due to time commitment than those who did not travel (3.713 ± 1.22) or teach (3.923 ± 0.929). We also found a difference in administrative responsibility across clinical settings (F6,194 = 3.507, P = .003). The results showed that GAATs in NCAA Division I clinical settings (44.55 ± 13.17 hours) worked more hours than those in NCAA Division III clinical settings (33.69 ± 12.07 hours) and those in high school settings (30.51 ± 9.934 hours). Conclusions: Graduate assistant ATs are at risk for burnout because of the time necessary to complete their clinical and academic responsibilities and their additional administrative responsibilities. Graduate assistants who work in the Division I clinical setting are at greater risk for burnout than those in the secondary school setting because of the large number of hours required. PMID:22892414
Athletic trainers' barriers to maintaining professional commitment in the collegiate setting.
Mazerolle, Stephanie M; Eason, Christianne M; Pitney, William A
2015-05-01
Professional commitment simply describes one's obligation to his or her work. For athletic trainers (ATs), the demanding work environment and job expectations may affect their characterization of professional commitment. Our breadth of knowledge regarding professional commitment within athletic training is narrow. To evaluate the professional commitment of ATs in the collegiate setting. Qualitative study. Collegiate. Thirty-three Board of Certification-certified ATs employed in the collegiate setting (National Collegiate Athletic Association Division I = 11, Division II = 9, Division III = 13) with an average of 10 ± 8 years of clinical experience volunteered. Data saturation guided the total number of participants. Online journaling via QuestionPro was completed by all participants. Multiple-analyst triangulation and peer review were conducted for data credibility. Analysis followed a general inductive method. Four themes speak to the factors that negatively affect ATs' professional enthusiasm and commitment: (1) life stage, (2) work overload, (3) organizational climate, and (4) human resources. The latter 3 speak to the effect the workplace can have on ATs' professional commitment, and the first speaks to the effect outside responsibilities can have. Our results suggest that several of the factors that negatively influence the professional commitment of collegiate ATs are modifiable organizational components. Developing resiliency strategies at the individual and organizational levels may help to facilitate improved professional commitment for the AT.
Fish everywhere, all the time: modeling fish in the riverscape
From 2002-2006, EPA’s Western Ecology Division conducted innovative research on the population dynamics of fish within an entire stream network. Employing individual tagging and tracking technology, we examined spatial patterns of juvenile coho salmon (Oncorhynchus kisutch...
Global Energy: Supply, Demand, Consequences, Opportunities (LBNL Summer Lecture Series)
Majumdar, Arun [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Environmental Energy Technologies Division; Univ. of California, Berkeley, CA (United States). Dept. of Materials Science and Engineering and Dept. of Mechanical Engineering
2018-05-04
Summer Lecture Series 2009: Arun Majumdar, Director of the Environmental Energy Technologies Division, discusses current and future projections of economic growth, population, and global energy demand and supply, and explores the implications of these trends for the environment.
Liao, K H; Gustafson, D L; Fox, M H; Chubb, L S; Reardon, K F; Yang, R S
2001-01-01
We modified the two-stage Moolgavkar-Venzon-Knudson (MVK) model for use with Syrian hamster embryo (SHE) cell neoplastic progression. Five phenotypic stages are proposed in this model: Normal cells can either become senescent or mutate into immortal cells followed by anchorage-independent growth and tumorigenic stages. The growth of normal SHE cells was controlled by their division, death, and senescence rates, and all senescent cells were converted from normal cells. In this report, we tested the modeling of cell kinetics of the first two phenotypic stages against experimental data evaluating the effects of arsenic on SHE cells. We assessed cell division and death rates using flow cytometry and correlated cell division rates to the degree of confluence of cell cultures. The mean cell death rate was approximately equal to 1% of the average division rate. Arsenic did not induce immortalization or further mutations of SHE cells at concentrations of 2 microM and below, and chromium (3.6 microM) and lead (100 microM) had similar negative results. However, the growth of SHE cells was inhibited by 5.4 microM arsenic after a 2-day exposure, with cells becoming senescent after only 16 population doublings. In contrast, normal cells and cells exposed to lower arsenic concentrations grew normally for at least 30 population doublings. The biologically based model successfully predicted the growth of normal and arsenic-treated cells, as well as the senescence rates. Mechanisms responsible for inducing cellular senescence in SHE cells exposed to arsenic may help explain the apparent inability of arsenic to induce neoplasia in experimental animals. PMID:11748027
Professional development of nursing in Saudi Arabia.
Tumulty, G
2001-01-01
To describe the development of nursing in Saudi Arabia and to recommend further directions for development of professional nursing in that country. A comprehensive needs assessment was performed in 1996 by an on-site consultant to: (a) evaluate the existing nursing system at the ministry, regional, and hospital levels, (b) describe the functional interrelationships of a nursing division within the Ministry of Health, and (c) prepare a work plan outlining the program elements that a nursing division could address to foster high-quality health care in the public sector. The needs assessment was conducted through direct observation, interviews, and review of existing documents in the Ministry of Health and representative hospitals, health centers, and health institutes. Data were collected about six factors as they pertained to the Ministry of Health Nursing Services: (a) key organizational and managerial activities, (b) the external environment, (c) the social system, (d) employees, (e) nursing services and research, and (f) formal organizational arrangements. The data showed a young country and an equally young nursing profession struggling to meet the needs of a growing population. The highest priority for the advancement of nursing in Saudi Arabia is the creation of a kingdom-wide system of nurse regulation. Pressing needs include regulation of professional standards, licensure of all nurses practicing in the Kingdom, accreditation of educational programs, and formation of a national nurses association.
Pre-disposition and epigenetics govern variation in bacterial survival upon stress.
Ni, Ming; Decrulle, Antoine L; Fontaine, Fanette; Demarez, Alice; Taddei, Francois; Lindner, Ariel B
2012-01-01
Bacteria suffer various stresses in their unpredictable environment. In response, clonal populations may exhibit cell-to-cell variation, hypothetically to maximize their survival. The origins, propagation, and consequences of this variability remain poorly understood. Variability persists through cell division events, yet detailed lineage information for individual stress-response phenotypes is scarce. This work combines time-lapse microscopy and microfluidics to uniformly manipulate the environmental changes experienced by clonal bacteria. We quantify the growth rates and RpoH-driven heat-shock responses of individual Escherichia coli within their lineage context, stressed by low streptomycin concentrations. We observe an increased variation in phenotypes, as different as survival from death, that can be traced to asymmetric division events occurring prior to stress induction. Epigenetic inheritance contributes to the propagation of the observed phenotypic variation, resulting in three-fold increase of the RpoH-driven expression autocorrelation time following stress induction. We propose that the increased permeability of streptomycin-stressed cells serves as a positive feedback loop underlying this epigenetic effect. Our results suggest that stochasticity, pre-disposition, and epigenetic effects are at the source of stress-induced variability. Unlike in a bet-hedging strategy, we observe that cells with a higher investment in maintenance, measured as the basal RpoH transcriptional activity prior to antibiotic treatment, are more likely to give rise to stressed, frail progeny.
Haq, Iqramul; Sakib, Saifullah; Talukder, Ashis
2017-12-06
Contraceptive use among married women of reproductive age has showed a substantial progress over the last few decades in Bangladesh. This study explores the sociodemographic factors associated with contraceptive use among ever-married women of reproductive age in Bangladesh by utilizing the information extracted from three of the Bangladesh Demographic and Health Surveys (BDHSs) in 1993-1994, 2004 and 2014. Bivariate analysis was conducted by performing chi-squared test of independence to explore the relationship between selected sociodemographic factors and dependent variables. To know the adjusted effects of covariates, a popular binary logistic regression model was considered. Respondents' current age, place residence, division religion, education, age at first marriage, family planning (FP) media exposure, ideal number of children and fertility preferences are the significant determinants according to the most recent survey, BDHS 2014. However, wealth index and a respondent's current working status were found to be significant factors only in BDHS 2004. The results of the study strongly recommend efforts to increase the education level among poor people, particularly among women in Bangladesh. Program interventions, including health behavior education and family planning services and counselling, are especially needed for some categories of the population, including those living in rural areas, Sylhet, Chittagong and Dhaka divisions, as well as illiterate and Muslim ever-married women.
[Gender systems and/in the Spanish National Health Interview Survey].
Ruiz Cantero, María Teresa; Papí Gálvez, Natalia; Carbrera Ruiz, Virginia; Ruiz Martínez, Ana; Alvarez-Dardet Díaz, Carlos
2006-01-01
To analyze the Spanish National Health Interview Survey (NHIS) from a gender perspective, with special emphasis on gender division of labor. We analyzed the 2003 Spanish NHIS from the perspective of the levels of gender observation, with gender understood as: a) the basis of social norms (responsibilities by sex, health risks, and problems related to masculine/feminine roles); b) the organizer of the social structure: gender division of labor, work overload, vertical/horizontal segregation, time spent in activities according to social times, access to resources), and c) a component of individual identity (conflicts due to multiple roles, body image dissatisfaction, self-esteem, self-perceived recognition of the work performed, assimilation of the sexual gender role, sex differences in health conditions). The Spanish NHIS is centered on the main provider, referred to in masculine grammatical form. Gender division of domestic labor is identified only by a general question. When using the concept of main activity for productive or reproductive work, the survey requires respondents to evaluate them and select only one, thus losing information and hampering analysis of the impact of an overload of work on health. Information on time used for reproductive work and leisure is not solicited. Assaults (intentional) and accidents (non-intentional) are combined in the same question, thus preventing research on gender-related violence. The Spanish NHIS includes the variable of sex, but its more descriptive than analytic focus limits gender analysis. The survey allows specific circumstances of employment-related inequalities between sexes to be measured, but does not completely allow other indicators of gender inequalities, such as the situation of housewives or work overload, to be measured.
Fulfillment of Work–Life Balance From the Organizational Perspective: A Case Study
Mazerolle, Stephanie M.; Goodman, Ashley
2013-01-01
Context: Researchers studying work–life balance have examined policy development and implementation to create a family-friendly work environment from an individualistic perspective rather than from a cohort of employees working under the same supervisor. Objective: To investigate what factors influence work–life balance within the National Collegiate Athletic Association (NCAA) Division I clinical setting from the perspective of an athletic training staff. Design: Qualitative study. Setting: Web-based management system. Patients or Other Participants: Eight athletic trainers (5 men, 3 women; age = 38 ± 7 years) in the NCAA Division I setting. Data Collection and Analysis: Participants responded to a series of questions by journaling their thoughts and experiences. We included data-source triangulation, multiple-analyst triangulation, and peer review to establish data credibility. We analyzed the data via a grounded theory approach. Results: Three themes emerged from the data. Family-oriented and supportive work environment was described as a workplace that fosters and encourages work–life balance through professionally and personally shared goals. Nonwork outlets included activities, such as exercise and personal hobbies, that provide time away from the role of the athletic trainer. Individualistic strategies reflected that although the athletic training staff must work together and support one another, each staff member must have his or her own personal strategies to manage personal and professional responsibilities. Conclusions: The foundation for a successful work environment in the NCAA Division I clinical setting potentially can center on the management style of the supervisor, especially one who promotes teamwork among his or her staff members. Although a family-friendly work environment is necessary for work–life balance, each member of the athletic training staff must have personal strategies in place to fully achieve a balance. PMID:24067152
DOE Office of Scientific and Technical Information (OSTI.GOV)
Jeff Neaton
Jan. 22, 2010: Host Alice Egan of Berkeley Lab's Materials Sciences Division interviews scientists about their lives and work in language everyone can understand. Her guest Berkeley Lab's MIke Crommie.
ERIC Educational Resources Information Center
Days, Drew S., III
In this speech the Assistant Attorney General for the Civil Rights Division of the Department of Justice discusses the impact of racial and sex discrimination on the nation. The author reflects on the high costs of discrimination, financially and socially, in terms of riot damage, underutilization of the work force, crime, and poor education. In…
A Kernel of Air Force Strategy: Diagnosis, Guiding Policy, and Coherent Action in the Late 1940s
2014-06-01
demobilization planning to a single person, Col C.H. Conrad Jr ., then working in the Army War Plans Division.8 Colonel Conrad hurriedly generated...troop strength, General Tompkins’ Project Planning Division underwent an organizational change. On July 22, 1943, Mr. Robert Patterson , the Under...26, 1948, British Prime Minister Ernest Bevin suggested that while the US airlift was buying time for negotiations, the United States should send
1991-05-01
FEASIBILITY STUDIES (RI/FS) ENVIRONMENTAL RESTORATION DIV STAFF MAY 1991 (REPRINT) - Distribution is unlimited; approved for public release ENVIRONMENTAL ...RESTORATION DIVISION (ESR) ENVIRONMENTAL SERVICES OFFICE AIR FORCE CENTER FOR ENVIRONMENTAL EXCELLENCE (AFCEE) BROOKS AIR FORCE BASE, TEXAS S(4 93-05296...Human Systems Division’s Human Systems Program Office, IRP Divisicn (HSD/YAQ) was transferred to the newly formed Air Force Center for Environmental
The Federal Role in Funding State and Local Infrastructure: Two Reports on Public Works Financing
1993-08-01
comments are welcome on any of these reports. For further information on the Federal Infrastructure Strategy Program, please contact Robert A. Pietrowsky ...Eugene Z. Stakhiv, Chief, Policy and Special Studies Division; and the FIS Study Team which includes Mr. Robert A. Pietrowsky , Program Manager, Mr...and visiting fellow of the Navigation Division of IWR, and Mr. Robert Pietrowsky for their helpful comments on the introduction. Mention must also be
2006-04-01
prepared by the Research and Animal Care Branch, Code 2351, of the Biosciences Division, Code 235, SSC San Diego. This is a work of the United...and Animal Care Branch Under authority of M. Rothe, Head Biosciences Division i EXECUTIVE SUMMARY In this study, we have evaluated peer... sharks , skates, and rays) and teleost fishes (modern bony fishes) and provide recommendations for research to address remaining issues. Clear responses
Mazerolle, Stephanie M; Eason, Christianne M
2015-08-01
A multilevel model of work-life balance (WLB) has been established in the sports management literature to explain interactions among organizational/structural, individual, and sociocultural factors and their effects on individual responses and attitudes toward WLB. These factors influence experiences and outcomes related to WLB. To examine individual and sociocultural factors that may influence perceptions of female athletic trainers (ATs) employed in the National Collegiate Athletic Association Division I setting, particularly any sex-specific influences. Qualitative study. National Collegiate Athletic Association Division I. A total of 27 women (14 single with no children, 6 married with no children, 7 married with children) currently employed as full-time ATs in the Division I setting participated. Participants responded to a series of open-ended questions via reflective journaling. Data were examined using a general inductive approach. Trustworthiness was established by multiple-analyst triangulation, member interpretive review, and peer review. Participants recognized that their sex played a role in assessing WLB and a long-term career as an AT. In addition, they identified various individual- and sociocultural-level factors that affected their perceptions of WLB and attitudes toward a career goal. Our data suggested that female ATs may hold traditional sex ideologies of parenting and family roles, which may influence their potential for career longevity.
Mirabello, Lisa; Vineis, Joseph H; Yanoviak, Stephen P; Scarpassa, Vera M; Póvoa, Marinete M; Padilla, Norma; Achee, Nicole L; Conn, Jan E
2008-03-26
Anopheles darlingi is the most important malaria vector in the Neotropics. An understanding of A. darlingi's population structure and contemporary gene flow patterns is necessary if vector populations are to be successfully controlled. We assessed population genetic structure and levels of differentiation based on 1,376 samples from 31 localities throughout the Peruvian and Brazilian Amazon and Central America using 5-8 microsatellite loci. We found high levels of polymorphism for all of the Amazonian populations (mean RS = 7.62, mean HO = 0.742), and low levels for the Belize and Guatemalan populations (mean RS = 4.3, mean HO = 0.457). The Bayesian clustering analysis revealed five population clusters: northeastern Amazonian Brazil, southeastern and central Amazonian Brazil, western and central Amazonian Brazil, Peruvian Amazon, and the Central American populations. Within Central America there was low non-significant differentiation, except for between the populations separated by the Maya Mountains. Within Amazonia there was a moderate level of significant differentiation attributed to isolation by distance. Within Peru there was no significant population structure and low differentiation, and some evidence of a population expansion. The pairwise estimates of genetic differentiation between Central America and Amazonian populations were all very high and highly significant (FST = 0.1859 - 0.3901, P < 0.05). Both the DA and FST distance-based trees illustrated the main division to be between Central America and Amazonia. We detected a large amount of population structure in Amazonia, with three population clusters within Brazil and one including the Peru populations. The considerable differences in Ne among the populations may have contributed to the observed genetic differentiation. All of the data suggest that the primary division within A. darlingi corresponds to two white gene genotypes between Amazonia (genotype 1) and Central America, parts of Colombia and Venezuela (genotype 2), and are in agreement with previously published mitochondrial COI gene sequences interpreted as incipient species. Overall, it appears that two main factors have contributed to the genetic differentiation between the population clusters: physical distance between the populations and the differences in effective population sizes among the subpopulations.
The Specific Features of design and process engineering in branch of industrial enterprise
NASA Astrophysics Data System (ADS)
Sosedko, V. V.; Yanishevskaya, A. G.
2017-06-01
Production output of industrial enterprise is organized in debugged working mechanisms at each stage of product’s life cycle from initial design documentation to product and finishing it with utilization. The topic of article is mathematical model of the system design and process engineering in branch of the industrial enterprise, statistical processing of estimated implementation results of developed mathematical model in branch, and demonstration of advantages at application at this enterprise. During the creation of model a data flow about driving of information, orders, details and modules in branch of enterprise groups of divisions were classified. Proceeding from the analysis of divisions activity, a data flow, details and documents the state graph of design and process engineering was constructed, transitions were described and coefficients are appropriated. To each condition of system of the constructed state graph the corresponding limiting state probabilities were defined, and also Kolmogorov’s equations are worked out. When integration of sets of equations of Kolmogorov the state probability of system activity the specified divisions and production as function of time in each instant is defined. On the basis of developed mathematical model of uniform system of designing and process engineering and manufacture, and a state graph by authors statistical processing the application of mathematical model results was carried out, and also advantage at application at this enterprise is shown. Researches on studying of loading services probability of branch and third-party contractors (the orders received from branch within a month) were conducted. The developed mathematical model of system design and process engineering and manufacture can be applied to definition of activity state probability of divisions and manufacture as function of time in each instant that will allow to keep account of loading of performance of work in branches of the enterprise.
Estimating division and death rates from CFSE data
NASA Astrophysics Data System (ADS)
de Boer, Rob J.; Perelson, Alan S.
2005-12-01
The division tracking dye, carboxyfluorescin diacetate succinimidyl ester (CFSE) is currently the most informative labeling technique for characterizing the division history of cells in the immune system. Gett and Hodgkin (Nat. Immunol. 1 (2000) 239-244) have proposed to normalize CFSE data by the 2-fold expansion that is associated with each division, and have argued that the mean of the normalized data increases linearly with time, t, with a slope reflecting the division rate p. We develop a number of mathematical models for the clonal expansion of quiescent cells after stimulation and show, within the context of these models, under which conditions this approach is valid. We compare three means of the distribution of cells over the CFSE profile at time t: the mean, [mu](t), the mean of the normalized distribution, [mu]2(t), and the mean of the normalized distribution excluding nondivided cells, .In the simplest models, which deal with homogeneous populations of cells with constant division and death rates, the normalized frequency distribution of the cells over the respective division numbers is a Poisson distribution with mean [mu]2(t)=pt, where p is the division rate. The fact that in the data these distributions seem Gaussian is therefore insufficient to establish that the times at which cells are recruited into the first division have a Gaussian variation because the Poisson distribution approaches the Gaussian distribution for large pt. Excluding nondivided cells complicates the data analysis because , and only approaches a slope p after an initial transient.In models where the first division of the quiescent cells takes longer than later divisions, all three means have an initial transient before they approach an asymptotic regime, which is the expected [mu](t)=2pt and . Such a transient markedly complicates the data analysis. After the same initial transients, the normalized cell numbers tend to decrease at a rate e-dt, where d is the death rate.Nonlinear parameter fitting of CFSE data obtained from Gett and Hodgkin to ordinary differential equation (ODE) models with first-order terms for cell proliferation and death gave poor fits to the data. The Smith-Martin model with an explicit time delay for the deterministic phase of the cell cycle performed much better. Nevertheless, the insights gained from analysis of the ODEs proved useful as we showed by generating virtual CFSE data with a simulation model, where cell cycle times were drawn from various distributions, and then computing the various mean division numbers.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Craig, D.F.
The division was formed in 1946 at the suggestion of Dr. Eugene P. Wigner to attack the problem of the distortion of graphite in the early reactors due to exposure to reactor neutrons, and the consequent radiation damage. It was called the Metallurgy Division and assembled the metallurgical and solid state physics activities of the time which were not directly related to nuclear weapons production. William A. Johnson, a Westinghouse employee, was named Division Director in 1946. In 1949 he was replaced by John H Frye Jr. when the Division consisted of 45 people. He was director during most ofmore » what is called the Reactor Project Years until 1973 and his retirement. During this period the Division evolved into three organizational areas: basic research, applied research in nuclear reactor materials, and reactor programs directly related to a specific reactor(s) being designed or built. The Division (Metals and Ceramics) consisted of 204 staff members in 1973 when James R. Weir, Jr., became Director. This was the period of the oil embargo, the formation of the Energy Research and Development Administration (ERDA) by combining the Atomic Energy Commission (AEC) with the Office of Coal Research, and subsequent formation of the Department of Energy (DOE). The diversification process continued when James O. Stiegler became Director in 1984, partially as a result of the pressure of legislation encouraging the national laboratories to work with U.S. industries on their problems. During that time the Division staff grew from 265 to 330. Douglas F. Craig became Director in 1992.« less
Wepfer, Ariane G; Brauchli, Rebecca; Jenny, Gregor J; Hämmig, Oliver; Bauer, Georg F
2015-12-24
The division of paid and unpaid labor in families continues to be highly gendered with men doing more paid work and women doing more unpaid care work. This is especially true for life stages with young children. Our study investigates the subjective experience of demands in the work and the private domain and the experience of work-life balance across family-life stages as a consequence of this gendered division of labor. We used data from a survey study on work-life issues and health in four large companies in Switzerland (N = 3664). In line with our hypotheses, subjective work and private demands were predicted by an interaction of family-life stages and gender. Specifically, during the primary child-rearing family-life stages, women experience more private demands than men while men experience more work demands, regardless of level of employment. Furthermore, women who work part time experience more work-life balance than women who work full time and more than men who work part or full time during the primary child-rearing family-life stages. Results are discussed in terms of a gendered work-life experience across the life course and the need for part-time work for both genders. Finally, conclusions are drawn concerning our results' implications for public health considerations.
Performance Evaluation of Various STL File Mesh Refining Algorithms Applied for FDM-RP Process
NASA Astrophysics Data System (ADS)
Ledalla, Siva Rama Krishna; Tirupathi, Balaji; Sriram, Venkatesh
2018-06-01
Layered manufacturing machines use the stereolithography (STL) file to build parts. When a curved surface is converted from a computer aided design (CAD) file to STL, it results in a geometrical distortion and chordal error. Parts manufactured with this file, might not satisfy geometric dimensioning and tolerance requirements due to approximated geometry. Current algorithms built in CAD packages have export options to globally reduce this distortion, which leads to an increase in the file size and pre-processing time. In this work, different mesh subdivision algorithms are applied on STL file of a complex geometric features using MeshLab software. The mesh subdivision algorithms considered in this work are modified butterfly subdivision technique, loops sub division technique and general triangular midpoint sub division technique. A comparative study is made with respect to volume and the build time using the above techniques. It is found that triangular midpoint sub division algorithm is more suitable for the geometry under consideration. Only the wheel cap part is then manufactured on Stratasys MOJO FDM machine. The surface roughness of the part is measured on Talysurf surface roughness tester.
Hemoparasites in Oregon spotted frogs (Rana pretiosa) from central Oregon, USA.
Stenberg, Patricia L; Bowerman, William J
2008-04-01
Between 2001 and 2003, we screened blood smears of 156 Oregon spotted frogs (Rana pretiosa) from three populations in central Oregon for blood parasites. A Lankesterella sp. and a Trypanosoma sp. were detected in 31% and 35% of the frogs, respectively. Parasite loads were generally light, with Lankesterella sporozoites in 1-2% of erythrocytes, and extracellular trypanosomes were seen at rates of about one parasite per 200 fields of view at 1,000x. Little work has been published on hemoparasites of ranids in the western USA in the past 30 yr. Because of the recent taxonomic division of the Rana pretiosa complex, this may be the first published report of blood parasites for R. pretiosa sensu stricto. Both parasites reported here differed in morphologic features and morphometric comparisons from previous descriptions of anuran hemoparasites. Much work remains to sort out the taxonomy of hemoparasites among western USA ranids and to determine the ecological significance of these parasites; both tasks are important steps in understanding and managing these, and related, sensitive and threatened species.
29 CFR 786.100 - Enforcement policy concerning performance of nonexempt work.
Code of Federal Regulations, 2010 CFR
2010-07-01
... employee during the workweek. [32 FR 15426, Nov. 4, 1967] ... workweek, unless the amount of such nonexempt work is substantial. For enforcement purposes, the amount of.... 786.100 Section 786.100 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION...
29 CFR 530.103 - Employer assurances.
Code of Federal Regulations, 2011 CFR
2011-07-01
... homeworkers shall be established using stop watch time studies or other work measurement methods. (h) All... Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS EMPLOYMENT... section 12. All homeworkers will be instructed not to permit minors to work in violation of such...
29 CFR 530.103 - Employer assurances.
Code of Federal Regulations, 2010 CFR
2010-07-01
... homeworkers shall be established using stop watch time studies or other work measurement methods. (h) All... Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS EMPLOYMENT... section 12. All homeworkers will be instructed not to permit minors to work in violation of such...
This report summarizes the recommended pollution prevention alternatives resulting from an investigation of operations at thePublic Works Center - Transportation Division (PWC-T) at Naval Station Mayport, located near Jacksonville Beach, Florida. il sampling and by-pass filtratio...
Code of Federal Regulations, 2010 CFR
2010-07-01
...) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR INTERPRETATION NOT DIRECTLY... hours which the employee will be likely to work at any time but should rather select a figure low enough...
29 CFR 778.315 - Payment for all hours worked in overtime workweek is required.
Code of Federal Regulations, 2010 CFR
2010-07-01
... OVERTIME COMPENSATION Special Problems Effect of Failure to Count Or Pay for Certain Working Hours § 778... 29 Labor 3 2010-07-01 2010-07-01 false Payment for all hours worked in overtime workweek is required. 778.315 Section 778.315 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION...
29 CFR 570.37 - Effect of this subpart on other laws.
Code of Federal Regulations, 2010 CFR
2010-07-01
... weeks, the participant is permitted to work during school hours on only one day per week, and for no... with the Administrator of the Wage and Hour Division a letter of application for approval of the work... participates in the work-study program, at least the minimum number of hours of classroom instruction, as...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-03
... Services, Working On-Site at Delphi Automotive Systems, LLC, Powertrain Division, El Paso, TX; Amended..., 2011, applicable to leased workers from Kelly Services working on-site at Delphi Automotive Systems... automotive components. The notice will be published soon in the Federal Register. At the request of the State...
29 CFR 785.23 - Employees residing on employer's premises or working at home.
Code of Federal Regulations, 2010 CFR
2010-07-01
... on employer's premises or working at home. An employee who resides on his employer's premises on a... 29 Labor 3 2010-07-01 2010-07-01 false Employees residing on employer's premises or working at home. 785.23 Section 785.23 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION...
Code of Federal Regulations, 2012 CFR
2012-10-01
... requirements for service contracts. Contracting specialists and contracting officers must work in close... review of requirements for service contracts. (1) Is the statement of work complete, with a clear-cut division of responsibility between the contracting parties? (2) Is the statement of work discussed in terms...
Code of Federal Regulations, 2014 CFR
2014-10-01
... requirements for service contracts. Contracting specialists and contracting officers must work in close... review of requirements for service contracts. (1) Is the statement of work complete, with a clear-cut division of responsibility between the contracting parties? (2) Is the statement of work discussed in terms...
Problems and potentialities of cultured plant cells in retrospect and prospect
NASA Technical Reports Server (NTRS)
Steward, F. C.; Krikorian, A. D.
1979-01-01
The past, present and expected future accomplishments and limitations of plant cell and tissue culture are reviewed. Consideration is given to the pioneering insights of Haberlandt in 1902, the development of culture techniques, and past work on cell division, cell and tissue growth and development, somatic embryogenesis, and metabolism and respiration. Current activity in culture media and technique development for plant regions, organs, tissues, cells, protoplasts, organelles and embryos, totipotency, somatic embryogenesis and clonal propagation under normal and space conditions, biochemical potentialities, and genetic engineering is surveyed. Prospects for the investigation of the induced control of somatic cell division, the division of isolated protoplasts, the improvement of haploid cell cultures, liquid cultures for somatic embryogenesis, and the genetic control of development are outlined.
Preliminary data on ASP2215: tolerability and efficacy in acute myeloid leukemia patients.
Thom, Claire
2015-09-01
Claire Thom speaks to Gemma Westcott, Commissioning Editor: Claire Thom joined Astellas in 2013 as the Therapeutic Area Head for Oncology in Global Development. In that role, she also serves as the STAR leader for Oncology for Astellas. Prior to Astellas, she spent 12 years with Takeda. Her last position was Senior Vice President, Portfolio Management, Drug Development Management and Medical Informatics and Strategic Operations within the Medical Division (the Division within Millennium responsible for oncology clinical drug development within Takeda). During her 4 years at Millennium, at various times, she had responsibility within the Medical Division for leading portfolio management, business operations (medical finance, annual and mid-range financial planning, space planning and operations, headcount resourcing, development goals process), clinical development operations (clinical operations, programming, data management, statistics, medical writing, clinical outsourcing), drug development management (project management), medical informatics (technology support for the division) and the strategic project management office for the division. Prior to joining Millennium, Claire Thom spent 18 months working in Osaka, Japan, during which she was responsible for developing the oncology strategy for Takeda that culminated in the acquisition of Millennium. Before going to Japan, she held positions of varying responsibility within the Takeda US development organization including the management of regulatory affairs, safety, biometrics and data management, clinical research and quality assurance. Claire Thom has particular expertise in organizational design and efficiency; she has successfully worked through integrations across multiple functions and redesigned business processes. She has a PharmD from University of Illinois (IL, USA) and over 20 years of pharmaceutical experience including positions in medical affairs and new product planning (over 11 years at Searle) and drug development (over 12 years at Takeda/Millennium).
ERIC Educational Resources Information Center
Byrd, Rebekah; Crockett, Stephanie A.; Erford, Bradley T.
2012-01-01
"The Journal for Specialists in Group Work" ("JSGW") is the journal of the Association for Specialists in Group Work (ASGW), a division of the American Counseling Association (ACA). "JSGW" publishes articles related to "group work theory, interventions, training, current issues, and research" (ASGW, 2011). "JSGW" was first published in 1976 and is…
The Political Demography of Bangladesh,
1972-04-13
ment by expanding the bureaucracy?) page seven d. The impact of population grcwth on gnera:tional cleavanges. Arv there division between political ... socialization experiences ancd therefore di1vergent pol.itical outlooKs%? To what extent are the cleavagecs in Bengalx politics - between the Auami League
Aflatoxin: An Old Carcinogen Teaches Us New Tricks | Division of Cancer Prevention
Speaker John D. Groopman, PhD Anna M. Baetjer Professor of Environmental Health Sciences Johns Hopkins Bloomberg School of Public Health Associate Director for Population Sciences Sidney Kimmel Comprehensive Cancer Center Johns Hopkins School of Medicine Baltimore, MD |
A description of the catalog division project at the College of Physicians of Philadelphia Library.
Caspari, S B; Batty, E L
1975-01-01
This paper describes the procedures used at the Library of the College of Physicians of Philadelphia to divide its ninety-year-old dictionary card catalog. The division was necessitated by overcrowding, obsolete subject headings, and lack of a complete authority list which resulted in like materials being scattered throughout the catalog under several headings. Two catalogs were created: the historical-biographical catalog, representing all works published before 1950 and all works of historical or biographical nature; and the current catalog, containing all works published from 1950 on, excepting historical or biographical materials. The 1950- catalog was further divided into name and subject catalogs, and the subject section was revised according to MeSH. The project was completed in about two years. As a result, searching time has been much reduced, and the library is able to take advantage of the annual revisions of MeSH to update the subject catalog. PMID:1173786
Ego Network Analysis of Upper Division Physics Student Survey
NASA Astrophysics Data System (ADS)
Brewe, Eric
2017-01-01
We present the analysis of student networks derived from a survey of upper division physics students. Ego networks focus on the connections that center on one person (the ego). The ego networks in this talk come from a survey that is part of an overall project focused on understanding student retention and persistence. The theory underlying this work is that social and academic integration are essential components to supporting students continued enrollment and ultimately graduation. This work uses network analysis as a way to investigate the role of social and academic interactions in retention and persistence decisions. We focus on student interactions with peers, on mentoring interactions with physics department faculty, and on engagement in physics groups and how they influence persistence. Our results, which are preliminary, will help frame the ongoing research project and identify ways in which departments can support students. This work supported by NSF grant #PHY 1344247.
2008-10-31
of the Apalachicola River drainage. Although this proposed division in classification appears to be generally accepted by the herpetological community...breeding in small forest ponds. Herpetological Review 33(4):275-280. Carle, F. L. and M. R. Strub. 1978. A new method for estimating population size...gopher frogs (Rana capito) and southern leopard frogs (Rana sphenocephala). Journal of Herpetology 42: 97-103. Grevstad, F.S. 2005. Simulating
Health Insurance Coverage: A Profile of the Uninsured in Selected States
1991-02-08
your request for profiles of individua1q .. . without health insurance.’ It presents income, employment, age , marital status, and other...Americans (under age 65),V or 15 percent of this population, did not have some form of health insurance coverage. Although uninsured rates varied among the...11.2: Uninsured Populations by Region, Division, 14 and State (1985) Table 111. 1: Health Insurance Coverage of Individuals 16 Under Age 65 in the
Elliott, Kayla R.; Harmatz, Jerold S.; Zhao, Yanli; Greenblatt, David J.
2016-01-01
Context: Collegiate football programs encourage athletes to pursue high body weights. Objective: To examine position-dependent trends over time in body size characteristics among football players in the National Collegiate Athletic Association Division III New England Small College Athletic Conference (NESCAC) from 1956 to 2014 and to compare the observed absolute and relative changes with those in age-matched male population controls. Design: Descriptive laboratory study. Setting: Medical school affiliated with a NESCAC institution. Patients or Other Participants: Football team rosters from the 10-member NESCAC schools, available as public documents, were analyzed along with body size data from general population males aged 20 to 29 years from the National Health and Nutrition Examination Survey (NHANES). Main Outcome Measure(s): Body weight, height, and calculated body mass index were evaluated using analysis of variance, linear regression, and nonlinear regression to determine the distribution features of size variables and changes associated with time (year), school, and position. Results: Among NESCAC linemen, absolute and relative changes over time in body weight and body mass index exceeded corresponding changes in the NHANES population controls. New England Small College Athletic Conference offensive linemen body weights increased by 37.5% from 1956 to 2014 (192 to 264 lb [86.4 to 118.8 kg]), compared with a 12% increase (164 to 184 lb [73.8 to 82.8 kg]) since 1961 in the NHANES population controls. Body mass index changed in parallel with body weight and exceeded 35 kg/m2 in more than 30% of contemporary NESCAC offensive linemen. Among skill players in the NESCAC group, time-related changes in body size characteristics generally paralleled those in the NHANES controls. Conclusions: High body weight and body mass indices were evident in offensive linemen, even among those in Division III football programs with no athletic scholarships. These characteristics may be associated with adverse cardiovascular and metabolic outcomes. We need approaches to encourage risk modification in the postfootball lifestyles of these individuals. PMID:27159189
Cell size control and homeostasis in bacteria
NASA Astrophysics Data System (ADS)
Bradde, Serena; Taheri, Sattar; Sauls, John; Hill, Nobert; Levine, Petra; Paulsson, Johan; Vergassola, Massimo; Jun, Suckjoon
2015-03-01
How cells control their size is a fundamental question in biology. The mechanisms for sensing size, time, or a combination of the two are not supported by experimental evidence. By analysing distributions of size at division at birth and generation time of hundreds of thousands of Gram-negative E. coli and Gram-positive B. subtilis cells under a wide range of tightly controlled steady-state growth conditions, we are now in the position to validate different theoretical models. In this talk I will present all possible models in details and present a general mechanism that quantitatively explains all measurable aspects of growth and cell division at both population and single-cell levels.
[Some similarities between the work of M.C. Escher and plastic surgery].
Marck, K W
2002-12-21
At first sight there would appear to be no similarities between the work of the Dutch graphic artist M.C. Escher and plastic surgery. M.C. Escher was a gifted graphic artist who produced a large collection of work. Most of his fame is due to the works that play with symmetry, space and infinity and leave the viewer astounded. However, how Escher came to produce these works is less well known. A theory which he developed himself formed the basis of the regular plane division. It later became apparent that this theory almost completely agreed with the mathematics of plane division. Two movements (isometries) defined in mathematics, translation and rotation, are equivalent to two techniques for transferring local skin in plastic surgery, namely, advancement and transposition. Escher's performance on the plane of a sheet of paper and a plastic surgeon's performance on the plane of the skin, therefore have a similar mathematical background. Escher has visualised these mathematical rules in an unusual and artistic manner, whereas plastic surgeons apply these rules in the grace of an elastic and healing nature.
Jenkins, Aaron Peter; Jupiter, Stacy; Mueller, Ute; Jenney, Adam; Vosaki, Gandercillar; Rosa, Varanisese; Naucukidi, Alanieta; Mulholland, Kim; Strugnell, Richard; Kama, Mike; Horwitz, Pierre
2016-12-01
The impact of environmental change on transmission patterns of waterborne enteric diseases is a major public health concern. This study concerns the burden and spatial nature of enteric fever, attributable to Salmonella Typhi infection in the Central Division, Republic of Fiji at a sub-catchment scale over 30-months (2013-2015). Quantitative spatial analysis suggested relationships between environmental conditions of sub-catchments and incidence and recurrence of typhoid fever. Average incidence per inhabited sub-catchment for the Central Division was high at 205.9/100,000, with cases recurring in each calendar year in 26% of sub-catchments. Although the numbers of cases were highest within dense, urban coastal sub-catchments, the incidence was highest in low-density mountainous rural areas. Significant environmental determinants at this scale suggest increased risk of exposure where sediment yields increase following runoff. The study suggests that populations living on large systems that broaden into meandering mid-reaches and floodplains with alluvial deposition are at a greater risk compared to small populations living near small, erosional, high-energy headwaters and small streams unconnected to large hydrological networks. This study suggests that anthropogenic alteration of land cover and hydrology (particularly via fragmentation of riparian forest and connectivity between road and river networks) facilitates increased transmission of typhoid fever and that environmental transmission of typhoid fever is important in Fiji.
Recent advances in the cell biology of aging.
Hayflick, L
1980-01-01
Cultured normal human and animal cells are predestined to undergo irreversible functional decrements that mimic age changes in the whole organism. When normal human embryonic fibroblasts are cultured in vitro, 50 +/- 10 population doublings occur. This maximum potential is diminished in cells derived from older donors and appears to be inversely proportional to their age. The 50 population doubling limit can account for all cells produced during a lifetime. The limitation on doubling potential of cultured normal cells is also expressed in vivo when serial transplants are made. There may be a direct correlation between the mean maximum life spans of several species and the population doubling potential of their cultured cells. A plethora of functional decrements occurs in cultured normal cells as they approach their maximum division capability. Many of these decrements are similar to those occurring in intact animals as they age. We have concluded that these functional decrements expressed in vitro, rather than cessation of cell division, are the essential contributors to age changes in intact animals. Thus, the study of events leading to functional losses in cultured normal cells may provide useful insights into the biology of aging.
29 CFR 5.12 - Debarment proceedings.
Code of Federal Regulations, 2010 CFR
2010-07-01
... THE CONTRACT WORK HOURS AND SAFETY STANDARDS ACT) Davis-Bacon and Related Acts Provisions and... Administrator of the Wage and Hour Division, Employment Standards Administration, U.S. Department of Labor... assisted construction work subject to any of the applicable statutes listed in § 5.1 and other labor...
Code of Federal Regulations, 2011 CFR
2011-07-01
... to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS CHILD LABOR REGULATIONS... when: (1) The apprentice is employed in a craft recognized as an apprenticeable trade; (2) the work of...) such work is intermittent and for short periods of time and is under the direct and close supervision...
Code of Federal Regulations, 2010 CFR
2010-07-01
... to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS CHILD LABOR REGULATIONS... when: (1) The apprentice is employed in a craft recognized as an apprenticeable trade; (2) the work of...) such work is intermittent and for short periods of time and is under the direct and close supervision...
29 CFR 541.202 - Discretion and independent judgment.
Code of Federal Regulations, 2011 CFR
2011-07-01
....202 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR... “matters of significance” refers to the level of importance or consequence of the work performed. (b) The... conducting the operations of the business; whether the employee performs work that affects business...
29 CFR 552.110 - Recordkeeping requirements.
Code of Federal Regulations, 2010 CFR
2010-07-01
..., (4) total hours worked each week by the employee for the employer, (5) total cash wages paid each... of daily and weekly hours that the employee normally works and either the employer or the employee... Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS APPLICATION...
High Technology and Education: An Economist's View.
ERIC Educational Resources Information Center
Carnoy, Martin
1988-01-01
Explores high technology industries' effects on labor markets, particularly on the division of labor, the organization of work, and the future of education. Discusses implications for demand and the distribution of that demand. Examines certain notions concerning knowledge production and work ethics and organization. Includes 34 references. (MLH)
29 CFR 541.702 - Exempt and nonexempt work.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 29 Labor 3 2010-07-01 2010-07-01 false Exempt and nonexempt work. 541.702 Section 541.702 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS DEFINING AND DELIMITING THE EXEMPTIONS FOR EXECUTIVE, ADMINISTRATIVE, PROFESSIONAL, COMPUTER AND OUTSIDE SALES EMPLOYEES...
Entrepreneurial Thinking in Interdisciplinary Student Teams
ERIC Educational Resources Information Center
Neumeyer, Xaver; McKenna, Ann
2016-01-01
Our work investigates students' perception of collaborative expertise and the role of inquiry-based learning in the context of team-based entrepreneurship education. Specifically, we examine students' perception of communication, division of work, shared goals, team conflicts and leadership in their respective teams. In addition, we look at the…
Does the Current 20th Century Navy Personnel Management System Meet 21st Century Sailors’ Needs
2003-04-01
symbols and our institutions. Technology moves non-human logic to center stage in our overall development. 10 Emile Durkheim in his seminal work, The...Management and Labor Economics Literature The Division of Labor in Society by Emile Durkheim explored the area of how complex societies demand a...the Future: The 1990’s and Beyond. New York: Penguin Books, 1992; Truman Talley Books/Plume, 1993. Durkheim , Emile . The Division of Labor in