Science.gov

Sample records for postradavshemu ot katastrofy

  1. MASTER: high amplitude OT

    NASA Astrophysics Data System (ADS)

    Balanutsa, P.; Pogrosheva, T.; Shumkov, V.; Lipunov, V.; Buckley, D.; Podesta, J. Stoffels R.; Levato, H.; Gorbovskoy, E.; Tiurina, N.; Balanutsa, P.; Kuznetsov, A.; Kornilov, V.; Chazov, V.; Vlasenko, D.; Vladimirov, V.; Gress, O.; Gorbunov, I.; Krylov, A.; Lopez, C.; Podesta, F.; Saffe, C.; Gabovich, A.

    2017-07-01

    MASTER-OAFA auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 17h 43m 42.12s -55d 30m 06.3s on 2017-07-03.05624 UT. The OT unfiltered magnitude is 16.5m (mlim=18.2m).

  2. Master: new OT

    NASA Astrophysics Data System (ADS)

    Gress, O.; Lipunov, V.; Buckley, D.; Gorbovskoy, E.; Kornilov, V.; Tiurina, N.; Balanutsa, P.; Kuznetsov, A.; Vladimirov, V.; Pogrosheva, T.; Chazov, V.; Shumkov, V.; Kuvshinov, D.

    2017-07-01

    MASTER-SAAO auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 15h 45m 44.73s -03d 21m 27.6s on 2017-07-16.74758 UT. The OT unfiltered magnitude is 17.5m (mlim=20.3).

  3. Master: 2 new OT

    NASA Astrophysics Data System (ADS)

    Shumkov, V.; Lipunov, V.; Buckley, D.; Tiurina, N.; Gorbovskoy, E.; Kuznetsov, A.; Balanutsa, P.; Kornilov, V.; Gress, O.; Vladimirov, V.; Kuvshinov, D.; Tlatov, A.; Senik, V.; Dormidontov, D.; Gabovich, A.; Pogrosheva, T.

    2017-01-01

    MASTER-SAAO auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 18h 58m 24.93s -69d 44m 51.3s on 2017-01-25.02720 UT. The OT unfiltered magnitude is 18.0m (mlim=19.0).

  4. Master: 2 OTs

    NASA Astrophysics Data System (ADS)

    Gress, O.; Balanutsa, P.; Lipunov, V.; Tlatov, A.; Senik, V.; Tiurina, N.; Gorbovskoy, E.; Kornilov, V.; Gorbunov, I.; Vlasenko, D.; Kuznetsov, A.; Zimnukhov, D.; Chazov, V.; Gabovich, A.

    2017-09-01

    MASTER-Kislovodsk auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 06h 51m 37.35s +70d 25m 59.3s on 2017-09-17.89615 UT. The OT unfiltered magnitude is 16.4m (limit 19.0m).

  5. MASTER Four OT's detection

    NASA Astrophysics Data System (ADS)

    Podvorotniy, P.; Balanutsa, P.; Lipunov, V.; Shumkov, V.; Gorbovskoy, E.; Tiurina, N.; Kornilov, V.; Belinski, A.; Shatskiy, N.; Chazov, V.; Kuznetsov, A.; Krushinsky, V.; Zimnukhov, D.; Zalozhnih, I.; Ivanov, K.; Popov, A.; Yazev, S.; Budnev, N.; Konstantinov, E.; Chuvalaev, O.; Poleshchuk, V.; Parkhomenko, A.; Gress, O.; Tlatov, A.; Dormidontov, D.; Yurkov, V.; Senik, V.; Sergienko, Y.; Varda, D.; Sinyakov, E.; Shurpakov, S.; Levato, Hugo; Saffe, Carlos; Mallamaci, Claudio; Lopez, Carlos; Podest, Federico

    2012-03-01

    MASTER163105.47+615548.4 - PSN MASTER-Tunka auto-detection system discovered OT source at (RA, Dec) = 16h 31m 05.47s +61d 55m 48.4s on 2012-03-14.83877 UT. The OT unfiltered magnitude is 18.1m (limit 19.8m). The OT is seen in 5 images. There is no minor planet at this place. There is one nonstar object in The Guide Star Catalog N4HU009709 with 1.3 arcsec offset (jmag=21.9). We have reference image without OT on 2011-05-01.72794 UT with unfiltered magnitude limit 20.1m.

  6. Overview of OT

    SciTech Connect

    Pate, R.; Dooley, R.B.

    1995-01-01

    At the last International Fossil Cycle Chemistry Conference in June 1991, a report was given on the Electric Power Research Institute (EPRI) sponsored project to study and transfer technology on the use of oxygenated feedwater treatment (OT). The report basically summarized the excellent results of employing OT worldwide, and updated the project activities which included development of an EPRI guidance document for implementation of OT in US utilities. Since the OT conversions of Georgia Power`s Wansley Unit No. 1 and Ohio Edison`s Sammis Unit 5 in November 1991, over 30 once-through units have subsequently been converted. In 1994, the first US drum unit was converted. The results have been outstanding with very large reductions of feedwater corrosion products (usually Fe<1 ppb at the economizer inlet) as a result of the more oxidizing environment (>+120 mV) and the change of the surface oxide layer from magnetite to ferric oxide hydrate (FeOOH) throughout the feedwater system. The benefits accrue because FeOOH blocks the pores of original Fe{sub 3}O{sub 4} reducing the transport of oxygen and iron ions through the layer. These surface layers of FeOOH also have a much lower solubility in flowing feedwater. This paper will provide an overview of the two supercritical/subcritical unit feedwater treatment technologies, (OT & AVT). In addition, the results of the two EPRI OT demonstration units (Wansley 1, Georgia Power Co. & Sammis 5, Ohio Edison) will be presented.

  7. MASTER-SAAO: blue OT and new short bright OT

    NASA Astrophysics Data System (ADS)

    Vladimirov, V.; Gress, O.; Lipunov, V.; Buckley, D.; Gorbovskoy, E.; Kornilov, V.; Chazov, V.; Tiurina, N.; Balanutsa, P.; Kuznetsov, A.; Gorbunov, I.; Vlasenko, D.; Shumkov, V.; Pogrosheva, T.; Kuvshinov, D.

    2017-07-01

    MASTER-SAAO auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 01h 11m 46.67s -81d 08m 21.2s on 2017-07-14.07693 UT. The OT unfiltered magnitude is 17.6m (mlim=20.0).

  8. MASTER-SAAO: OTs detection

    NASA Astrophysics Data System (ADS)

    Gress, O.; Lipunov, V.; Buckley, D.; Gorbovskoy, E.; Balanutsa, P.; Tiurina, N.; Kuznetsov, A.; Kornilov, V.; Pogrosheva, T.; Shumkov, V.; Vladimirov, V.; Vlasenko, D.; Kuvshinov, D.; Gabovich, A.

    2017-07-01

    MASTER-SAAO auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 18h 04m 09.47s -76d 13m 37.3s on 2017-06-30.81575 UT. The OT unfiltered magnitude is (mlim=19.0).

  9. Master-Oafa new OT

    NASA Astrophysics Data System (ADS)

    Shumkov, V.; Lipunov, V.; Podesta, R.; Levato, H.; Gorbovskoy, E.; Tiurina, N.; Pogrosheva, T.; Balanutsa, P.; Kuznetsov, A.; Kornilov, V.; Chazov, V.; Vlasenko, D.; Vladimirov, V.; Gress, O.; Gorbunov, I.; Krylov, A.; Lopez, C.; Podesta, F.; Saffe, C.; Gabovich, A.

    2017-06-01

    MASTER-OAFA auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 13h 32m 57.09s -31d 43m 51.0s on 2017-06-20.11831 UT. The OT unfiltered magnitude is (mlim=19.6m).

  10. MASTER: QSO flare and OTs

    NASA Astrophysics Data System (ADS)

    Gress, O.; Shumkov, V.; Pogrosheva, T.; Lipunov, V.; Rebolo, R.; Serra-Ricart, M.; Podesta, R.; Levato, H.; Gorbovskoy, E.; Tiurina, N.; Balanutsa, P.; Kuznetsov, A.; Kornilov, V.; Ivanov, K.; Vladimirov, V.; Lopez, C.; Podesta, F.; Saffe, C.

    2016-10-01

    MASTER-OAFA auto-detection system (Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 01h 50m 52.97s -45d 10m 15.9s on 2016-10-06.21896 UT with unfiltered m_OT=17.4m (limit 20.6m).

  11. MASTER: PSN and new OT

    NASA Astrophysics Data System (ADS)

    Balanutsa, P.; Gorbovskoy, E.; Lipunov, V.; Rebolo, R.; Serra-Ricart, M.; Budnev, N.; Gress, O.; Ivanov, K.; Tiurina, N.; Kuznetsov, A.; Kornilov, V.; Vladimirov, V.; Chazov, V.; Shumkov, V.; Pogrosheva, T.; Postnikov, L.; Nikitin, V.; Kuvshinov, D.

    2017-01-01

    MASTER-Tunka auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 07h 50m 43.35s +79d 09m 16.6s on 2017-01-23.88841 UT. The OT unfiltered magnitude is 17.8m (limit 19.6m).

  12. MASTER-Kislovodsk: bright OT

    NASA Astrophysics Data System (ADS)

    Shurpakov, S.; Lipunov, V.; Kornilov, V.; Gorbovskoy, E.; Tiurina, N.; Gress, O.; Balanutsa, P.; Gorbunov, I.; Vladimirov, V.; Shumkov, V.; Pogrosheva, T.; Tlatov, A.; Senik, V.; Gabovich, A.

    2017-09-01

    MASTER-Kislovodsk auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 19h 24m 41.01s , +62d 06m 39s.4 on 2017-09-10.87104 UT. The OT unfiltered magnitude is 15.4m (limit 18.9m).

  13. Rapid OT discovered by MASTER

    NASA Astrophysics Data System (ADS)

    Balanutsa, P.; Gorbovskoy, E.; Lipunov, V.; Denisenko, D.; Tiurina, N.; Kornilov, V.; Belinski, A.; Shatskiy, N.; Chazov, V.; Kuznetsov, A.; Zimnukhov, D.; Krushinsky, V.; Zalozhnih, I.; Popov, A.; Bourdanov, A.; Punanova, A.; Ivanov, K.; Yazev, S.; Budnev, N.; Konstantinov, E.; Chuvalaev, O.; Poleshchuk, V.; Gress, O.; Parkhomenko, A.; Tlatov, A.; Dormidontov, D.; Senik, V.; Yurkov, V.; Sergienko, Y.; Varda, D.; Sinyakov, E.; Shumkov, V.; Shurpakov, S.; Levato, H.; Saffe, C.; Mallamaci, C.; Lopez, C.; Podest, F.

    2012-09-01

    OT MASTER J005552.55+261100.8 discovery MASTER-Amur auto-detection system discovered OT source at (RA, Dec) = 00h 55m 52.55s +26d 11m 00.8s on 2012-08-30.77359 UT by two tube simultaneously during 3 min exposition. The OT unfiltered magnitude is 14.2m (limit 18.0m). There is no minor planet at this place. There is no known satellite around 4 degrees at this time. There is one non star object NBKY021338 (jmag~ 22.3) in the Guide Star Catalog with 3.6 arcsec offset.

  14. a0o-+ts

    Center for Drug Evaluation (CDER)

    - a0o-+ts- oa(qa LN- bCt ~&ZAR~~ ~~ 98.1 -1: s '~ R"T -kane- ~Dan eT --tie, GZ,S~ov►~ % vi 0 8 9 9 ~~AiWt~~~~ ~ A~ Q ,tylk, W(`~~ ~ wotv-s ...

  15. MASTER: high amplitude OT and OT during Fermi inspection

    NASA Astrophysics Data System (ADS)

    Balanutsa, P.; Lipunov, V.; Rebolo, R.; Serra-Ricart, M.; Podesta, R.; Levato, H.; Buckley, D.; Gorbovskoy, E.; Tiurina, N.; Shumkov, V.; Gress, O.; Pogrosheva, T.; Kuznetsov, A.; Kornilov, V.; Chazov, V.; Vlasenko, D.; Vladimirov, V.; Gorbunov, I.; Krylov, A.; Lopez, C.; Podesta, F.; Saffe, C.; Gabovich, A.

    2017-06-01

    During trigger (short GRB)/ (GRB_TIME: 17/06/04 14:28:05.09 UT, GRB_RA,Dec(2000):22h 41m 46s,+40d 40' 12", GRB_ERROR: 4.10 [deg radius, statistical only] )inspection MASTER-Kislovodsk auto-detection system detected optical transient at (RA, Dec) = 23h 01m 48.65s +41d 19m 04.2s on 2017-06-04.97120 UT. The OT unfiltered magnitude is 19.2m (limit 19.3m).

  16. Time comparison via OTS-2

    NASA Technical Reports Server (NTRS)

    Dejong, G.; Kaarls, R.; Kirchner, D.; Ressler, H.

    1982-01-01

    The time comparisons carried out via OTS-2 between the Technical University Graz (Austria) and the Van Swinden Laboratory Delft (Netherlands) are discussed. The method is based on the use of the synchronization pulse in the TV-frame of the daily evening broadcasting of a French TV-program to Northern Africa. Corrections, as a consequence of changes in the position of the satellite coordinates are applied weekly after reception of satellite coordinates. A description of the method is given as well as some of the particular techniques used in both the participating laboratories. Preliminary results are presented.

  17. MASTER-OAFA: OT detection during inspection

    NASA Astrophysics Data System (ADS)

    Gress, O.; Lipunov, V.; Podesta, R.; Levato, H.; Gorbovskoy, E.; Tiurina, N.; Kuznetsov, A.; Balanutsa, P.; Kornilov, V.; Chazov, V.; Gorbunov, I.; Krylov, A.; Lopez, C.; Podesta, F.; Saffe, C.; Shumkov, V.; Pogrosheva, T.

    2017-02-01

    MASTER-OAFA auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 18h 36m 27.60s -47d 35m 18.1s on 2017-02-02.36706 UT. The OT unfiltered magnitude is 16.2m (mlim=18.1m).

  18. MASTER: new OT and QSO flare

    NASA Astrophysics Data System (ADS)

    Balanutsa, P.; Lipunov, V.; Buckley, D.; Budnev, N.; Gress, O.; Gorbovskoy, E.; Tiurina, N.; Vladimirov, V.; Kornilov, V.; Kuvshinov, D.; Pogrosheva, T.; Ivanov, K.

    2017-02-01

    MASTER-SAAO auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 09h 45m 05.87s -65d 43m 43.3s on 2017-02-15.91771 UT. The OT unfiltered magnitude is (mlim=18.6).

  19. MASTER-OAFA discovery: new bright OT

    NASA Astrophysics Data System (ADS)

    Shumkov, V.; Balanutsa, P.; Pogrosheva, T.; Lipunov, V.; Podesta, R.; Levato, H.; Buckley, D.; Gorbovskoy, E.; Tiurina, N.; Kuznetsov, A.; Kornilov, V.; Chazov, V.; Vlasenko, D.; Vladimirov, V.; Gress, O.; Ivanov, K.; Lopez, C.; Podesta, F.; Saffe, C.; Potter, S.

    2016-10-01

    MASTER-OAFA auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 18h 06m 06.62s -62d 13m 31.3s on 2016-10-19.03627 UT. The OT unfiltered (limit 19.1m).

  20. MASTER: bright OT during Fermi trigger inspection

    NASA Astrophysics Data System (ADS)

    Shumkov, V.; Lipunov, V.; Budnev, N.; Gress, O.; Gorbovskoy, E.; Tiurina, N.; Balanutsa, P.; Kuznetsov, A.; Vlasenko, D.; Vladimirov, V.; Kuvshinov, D.; Chazov, V.; Gorbunov, I.; Zimnuhov, D.

    2017-10-01

    MASTER-Tunka auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 06h 20m 10.45s +54d 46m 57.8s on 2017-09-28.56648 UT. The OT magnitude in unfiltered is 16.1m (limit 18.2m).

  1. MASTER: 2 OT discovered in Argentina

    NASA Astrophysics Data System (ADS)

    Shumkov, V.; Pogrosheva, T.; Lipunov, V.; Podesta, R.; Levato, H.; Gorbovskoy, E.; Tiurina, N.; Balanutsa, P.; Kuznetsov, A.; Vladimirov, V.; Gress, O.; Ivanov, K.; Chazov, V.; Lopez, C.; Podesta, F.; Saffe, C.

    2016-10-01

    MASTER-OAFA, located in Argentina, with auto-detection system (Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L) discovered OT source at (RA, Dec) = 03h 19m 42.92s -45d 30m 13.9s on 2016-10-27.27597 UT. The OT unfiltered magnitude is 16.9m (mlim=20.8m).

  2. MASTER-IAC: QSO flare and OT

    NASA Astrophysics Data System (ADS)

    Shumkov, V.; Balanutsa, P.; Lipunov, V.; Rebolo, R.; Serra-Ricart, M.; Kornilov, V.; Gorbovskoy, E.; Tiurina, N.; Gorbunov, I.; Pogrosheva, T.; Chazov, V.; Kuznetsov, A.; Vlasenko, D.; Gress, O.; Gabovich, A.

    2017-05-01

    MASTER-IAC auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 16h 37m 46.50s +11d 49m 50.0s on 2017-05-06 2017-05-06 01:43:58UT . The OT unfiltered magnitude is 16.3 (mlim=19.6).It was 17.0m at min state on 2016-04-27 02:35:08.773UT There is QSO in 0.43" (Hewitt+ 1993, Schneider+ 2010, et al) The discovery and reference image are available at http://master.sai.msu.ru/static/OT/MASTEROTJ163746.5+114950.0.jpg MASTER-IAC auto-detection system discovered OT source at (RA, Dec) = 18h 16m 24.72s +07d 32m 52.7s on 2017-05-07.19602 UT. The OT unfiltered magnitude is 18.6m (limit 19.2m).

  3. MASTER: OT detection during Fermi trigger inspection

    NASA Astrophysics Data System (ADS)

    Popova, E.; Lipunov, V.; Buckley, D.; Gorbovskoy, E.; Tiurina, N.; Balanutsa, P.; Kuznetsov, A.; Kornilov, V.; Chazov, V.; Vlasenko, D.; Vladimirov, V.; Gress, O.; Ivanov, K.; Potter, S.; Gabovich, A.

    2016-11-01

    During inspection of Fermi trigger 501261070 ( (Ra,Dec)=47.190,-47.210; GRB_ERROR_radius=3.27deg, GRB_TIME=2016/11/19 15:11:06.40UT http://gcn.gsfc.nasa.gov/other/501261070.fermi ) MASTER-SAAO auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 03h 22m 52.70s -48d 29m 10.9s on 2016-11-19 21:17:17.878UT with unfiltered m_OT=17.8 (mlim=19.7).

  4. CNEOST OT PTSS-17dmk, discovery - new OT, no VIZIER data

    NASA Astrophysics Data System (ADS)

    Li, Bin; Zhao, Haibin; Wang, Xiaofeng; Li, Wenxiong; Xu, Zhijian; Tan, Hanjie; Wang, Lifan; Zhang, Jujia

    2017-03-01

    PTSS (Purple Mountain Observtory(PMO) & Tsinghua Supernova Survey ) discovered OT source PTSS-17jdx at (RA, Dec) = 13h20m53.59s -04d14m04.70s on 2017-02-07.727524 UT with the 1.04/1.8 Schmidt Telescope( named Chinese Near Earth Object Survey Telescope , CNEOST ) at Xuyi station of PMO. The OT PTSS-17jdx SDSS-r magnitude is 17.5m.

  5. CNEOST OT PTSS-17dmk, discovery - new OT, no VIZIER data

    NASA Astrophysics Data System (ADS)

    Li, Bin; Zhao, Haibin; Wang, Xiaofeng; Li, Wenxiong; Xu, Zhijian; Tan, Hanjie; Wang, Lifan; Zhang, Jujia

    2017-03-01

    PTSS (Purple Mountain Observtory(PMO) & Tsinghua Supernova Survey ) discovered OT source PTSS-17jdx at (RA, Dec) = 13h20m53.59s -04d14m04.70s on 2017-02-07.727524 UT with the 1.04/1.8 Schmidt Telescope( named Chinese Near Earth Object Survey Telescope , CNEOST ) at Xuyi station of PMO. The OT PTSS-17jdx SDSS-r magnitude is 17.5m.

  6. 12 CFR 510.5 - Release of unpublished OTS information.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... disclosure of that information; (3) To ensure that the time of OTS employees is utilized in the most... information sought, including the relevant time period. (ii) When the OTS believes that another person has a... for OTS testimony in sufficient time to request and obtain that testimony in deposition form. A...

  7. MASTER-SAAO: fast blue OT

    NASA Astrophysics Data System (ADS)

    Pogrosheva, T.; Lipunov, V.; Buckley, D.; Kornilov, V.; Gorbovskoy, E.; Tiurina, N.; Balanutsa, P.; Kuznetsov, A.; Gress, O.; Vlasenko, D.; Chazov, V.; Vladimirov, V.; Kuvshinov, D.; Gabovich, A.

    2017-06-01

    MASTER-SAAO auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 15h 17m 34.48s -27d 10m 17.6s on 2017-06-01.79735 UT. The OT unfiltered (W=0.2B+0.8R calibrated by thousands USNO-B1 fields stars) magnitudes are: 2017-06-01 19:08:11UT 17.8 2017-06-01 19:25:44UT 18.2 2017-06-01 19:40:03UT 2017-06-01 19:41:32UT 19.0(=mlim) Every exposition was 60s http://observ.pereplet.ru/images/MASTEROTJ151734.48-271017.6.gif We have reference image on 2016-07-09.83249 UT with unfiltered mlim= 20.9m.

  8. CNEOST OT PTSS-17dmk, discovery - new OT, no VIZIER data

    NASA Astrophysics Data System (ADS)

    Li, Bin; Zhao, Haibin; Wang, Lifan; Xu, Zhijian; Li, Wenxiong; Wang, Xiaofeng; Tan, Hanjie; Rui, Liming; Yang, Zesheng

    2017-02-01

    PTSS (Purple Mountain Observtory(PMO) & Tsinghua Supernova Survey ) discovered OT source at (RA, Dec) = 05h 28m 21.88s +59d 38m 39.26s on 2017-02-09.557376 UT with the 1.04/1.8 Schmidt Telescope( named Chinese Near Earth Object Survey Telescope , CNEOST http://www.cneost.org ) at Xuyi station of PMO. The OT (PTSS-17dmk) SDSS-r magnitude is 17.2m (limit 18.7m).

  9. CNEOST OT PTSS-17dmk, discovery - new OT, no VIZIER data

    NASA Astrophysics Data System (ADS)

    Li, Bin; Zhao, Haibin; Wang, Lifan; Xu, Zhijian; Li, Wenxiong; Wang, Xiaofeng; Tan, Hanjie; Rui, Liming; Yang, Zesheng

    2017-02-01

    PTSS (Purple Mountain Observtory(PMO) & Tsinghua Supernova Survey ) discovered OT source at (RA, Dec) = 05h 28m 21.88s +59d 38m 39.26s on 2017-02-09.557376 UT with the 1.04/1.8 Schmidt Telescope( named Chinese Near Earth Object Survey Telescope , CNEOST http://www.cneost.org ) at Xuyi station of PMO. The OT (PTSS-17dmk) SDSS-r magnitude is 17.2m (limit 18.7m).

  10. 12 CFR 500.10 - The OTS or The Office.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 6 2014-01-01 2012-01-01 true The OTS or The Office. 500.10 Section 500.10 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY AGENCY ORGANIZATION AND FUNCTIONS General Organization § 500.10 The OTS or The Office. The Office of Thrift Supervision (referred to...

  11. 75 FR 51169 - OTS Minority Depository Institutions Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-18

    ... Office of Thrift Supervision OTS Minority Depository Institutions Advisory Committee AGENCY: Department... Minority Depository Institutions Advisory Committee will renew for a two-year period beginning August 2...), and with the approval of the Secretary of the Treasury to announce the renewal of the OTS...

  12. 12 CFR 574.7 - Determination by the OTS.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... SAVINGS ASSOCIATIONS § 574.7 Determination by the OTS. (a) Acquisition by a company. (1) The Office shall... company are composed of persons who, at the time of acquisition, are executive officers and directors of... acquisition, the holding company shall file with the OTS a certification by legal counsel stating the...

  13. 12 CFR 510.5 - Release of unpublished OTS information.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... used or would not be adequate at the trial or hearing. (iv) The OTS shall specify the scope of any... ORGANIZATIONAL REGULATIONS § 510.5 Release of unpublished OTS information. (a) Scope. (1) This section applies to... request and obtain that testimony in deposition form. A request for testimony at a trial or hearing may...

  14. 12 CFR 510.5 - Release of unpublished OTS information.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... used or would not be adequate at the trial or hearing. (iv) The OTS shall specify the scope of any... ORGANIZATIONAL REGULATIONS § 510.5 Release of unpublished OTS information. (a) Scope. (1) This section applies to... request and obtain that testimony in deposition form. A request for testimony at a trial or hearing may...

  15. 12 CFR 510.5 - Release of unpublished OTS information.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... used or would not be adequate at the trial or hearing. (iv) The OTS shall specify the scope of any... ORGANIZATIONAL REGULATIONS § 510.5 Release of unpublished OTS information. (a) Scope. (1) This section applies to... request and obtain that testimony in deposition form. A request for testimony at a trial or hearing may...

  16. MASTER-SAAO: OT detected during Fermi 508270281 inspection

    NASA Astrophysics Data System (ADS)

    Pogrosheva, T.; Balanutsa, P.; Lipunov, V.; Buckley, D.; Gorbovskoy, E.; Tiurina, N.; Gress, O.; Shumkov, V.; Kuznetsov, A.; Kornilov, V.; Chazov, V.; Potter, S.

    2017-02-01

    MASTER-SAAO auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 11h 34m 18.80s -51d 33m 13.5s on 2017-02-08.93060 UT. The OT unfiltered magnitude is (mlim=18.4).

  17. Master-Saao Psn in PGC152788 and OT

    NASA Astrophysics Data System (ADS)

    Balanutsa, P.; Gress, O.; Lipunov, V.; Buckley, D.; Gorbovskoy, E.; Tiurina, N.; Kuznetsov, A.; Kornilov, V.; Vladimirov, V.; Chazov, V.; Kuvshinov, D.; Pogrosheva, T.; Shumkov, V.

    2017-02-01

    MASTER-SAAO auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 08h 32m 56.92s -03d 51m 28.1s on 2017-02-11 22:13:06.767UT . The OT unfiltered magnitude is (mlim=19.8).

  18. MASTER-OAFA, MASTER-SAAO discovery: bright OTs

    NASA Astrophysics Data System (ADS)

    Pogrosheva, T.; Shumkov, V.; Popova, E.; Lipunov, V.; Podesta, R.; Levato, H.; Buckley, D.; Lopez, C.; Podesta, F.; Saffe, C.; Potter, S.; Gorbovskoy, E.; Balanutsa, P.; Tiurina, N.; Kuznetsov, A.; Kornilov, V.; Vladimirov, V.; Gress, O.; Chazov, V.; Ivanov, K.

    2016-11-01

    MASTER-OAFA (located in Argentina) auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 20h 26m 36.17s -44d 07m 22.7s on 2016-11-29.04023 UT. The OT unfiltered magnitude is (mlim=18.6m).

  19. Fast bright OT in PGC2697102 discovered by MASTER

    NASA Astrophysics Data System (ADS)

    Shumkov, V.; Lipunov, V.; Tlatov, A.; Gorbovskoy, E.; Chazov, V.; Tiurina, N.; Kuznetsov, A.; Balanutsa, P.; Kornilov, V.; Vladimirov, V.; Gress, O.; Ivanov, K.; Kuvshinov, D.; Senik, V.; Dormidontov, D.; Parkhomenko, A.; Gabovich, A.

    2016-11-01

    MASTER-Kislovodsk auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 16h 15m 32.60s +67d 14m 45.8s on 2016-11-10.73375 UT. The OT unfiltered magnitude is (mlim=18.7m).

  20. MASTER: PSN in 2MASS galaxy and OT

    NASA Astrophysics Data System (ADS)

    Pogrosheva, T.; Lipunov, V.; Rebolo, R.; Serra-Ricart, M.; Podesta, R.; Levato, H.; Kornilov, V.; Popova, E.; Tiurina, N.; Gorbovskoy, E.; Balanutsa, P.; Chazov, V.; Kuznetsov, A.; Gress, O.; Shumkov, V.; Gorbunov, I.; Vlasenko, D.; Lopez, C.; Podesta, F.; Saffe, C.

    2017-05-01

    MASTER-IAC auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 16h 06m 56.39s +15d 40m 46.2s on 2017-05-29.98135 UT. The OT unfiltered magnitude is 17.4m (limit 19.2m).

  1. 76 FR 7630 - Open Meeting of the OTS Minority Depository Institutions Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-10

    ... Office of Thrift Supervision Open Meeting of the OTS Minority Depository Institutions Advisory Committee... OTS Minority Depository Institutions Advisory Committee (MDIAC) will convene a meeting on Tuesday..., the Office of Thrift Supervision is announcing that the OTS Minority Depository Institutions...

  2. 75 FR 13344 - Open Meeting of the OTS Minority Depository Institutions Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-19

    ... Office of Thrift Supervision Open Meeting of the OTS Minority Depository Institutions Advisory Committee... OTS Minority Depository Institutions Advisory Committee (MDIAC) will convene a meeting on Wednesday... Supervision is announcing that the OTS Minority Depository Institutions Advisory Committee will convene...

  3. 12 CFR 500.10 - The OTS or The Office.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Senate to a five-year term. The Director directs and carries out the mission of the OTS with the assistance of offices reporting directly to him. One of these offices oversees the direct examination and...

  4. MASTER: OT inside Fermi 524493492 error-box

    NASA Astrophysics Data System (ADS)

    Tiurina, N.; Lipunov, V.; Lopez, R. Rebolo; Serra-Ricart, M.; Kornilov, V.; Gorbovskoy, E.; Balanutsa, P.; Kuznetsov, A.; Chazov, V.; Vlasenko, D.; Vladimirov, V.; Gress, O.; Podesta, R.; Lopez, C.; Podesta, F.; Francile, C.; Levato, H.; Saffe, C.; Gabovich, A.; Sergienko, Yu.; Yurkov, V.; Shumkov, V.; Pogrosheva, T.

    2017-08-01

    MASTER-Kislovodsk auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 21h 16m 43.97s +33d 58m 00.4s on 2017-08-15.78324 UT. We have 2 inspect images and the OT unfiltered magnitude is 17.6 m (limit 19.0m) on both of them.

  5. MASTER: OT discovered during inspection of HESE 58537957 trigger

    NASA Astrophysics Data System (ADS)

    Tyurina, N.; Lipunov, V.; Buckley, D.; Gorbovskoy, E.; Balanutsa, P.; Kuznetsov, A.; Kornilov, V.; Kuvshinov, D.; Vlasenko, D.; Gress, O.; Ivanov, K.; Shumkov, V.; Potter, S.

    2016-08-01

    MASTER-SAAO auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 349171 ) discovered OT source at (RA, Dec) = 13h 08m 45.02s -32d 32m 54.9s on 2016-08-24.73811 UT during inspection of HESE alert ( 58537957 trigger number ) http://gcn.gsfc.nasa.gov/notices_amon/58537957_128340.amon . The OT unfiltered magnitude is 19.6m (limit 20.5m).

  6. MASTER-IAC: new OT during Fermi trigger 524719044 inspection

    NASA Astrophysics Data System (ADS)

    Vladimirov, V.; Lipunov, V.; Lopez, R. Rebolo; Serra-Ricart, M.; Gorbovskoy, E.; Tiurina, N.; Kornilov, V.; Gress, O.; Balanutsa, P.; Kuznetsov, A.; Zimnukhov, D.

    2017-08-01

    MASTER-IAC auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 21h 01m 41.71s +23d 26m 38.9s on 2017-08-19.05138 UT during Fermi trigger 524719044 inspection GCN #21573 The OT unfiltered magnitude was 17.3m (limit 18.1m).

  7. MASTER-IAC: very bright high amplitude OT

    NASA Astrophysics Data System (ADS)

    Balanutsa, P.; Lipunov, V.; Rebolo, R.; Serra-Ricart, M.; Lodieu, N.; Buckley, D.; Gorbovskoy, E.; Tiurina, N.; Kuznetsov, A.; Vladimirov, V.; Kornilov, V.; Chazov, V.; Kuvshinov, D.; Gress, O.; Budnev, N.; Ivanov, K.

    2016-12-01

    MASTER-IAC auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 03h 02m 05.67s +25d 48m 34.3s on 2016-12-04.96045 UT. The OT unfiltered magnitude is 13.7m (m_limit=20.3m).

  8. 2 new OT, discovered by MASTER-OAFA (Argentina)

    NASA Astrophysics Data System (ADS)

    Shumkov, V.; Lipunov, V.; Podesta, R.; Levato, H.; Gorbovskoy, E.; Tiurina, N.; Kuznetsov, A.; Vladimirov, V.; Balanutsa, P.; Kornilov, V.; Gress, O.; Chazov, V.; Kuvshinov, D.; Lopez, C.; Podesta, F.; Saffe, C.; Gabovich, A.

    2016-11-01

    MASTER-OAFA (located in Argentina) auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 09h 23m 26.72s -76d 28m 17.7s on 2016-11-13 06:19:38UT The OT magnitude in unfiltered is (mlim=18.0m).

  9. OT promotes closer interpersonal distance among highly empathic individuals.

    PubMed

    Perry, Anat; Mankuta, David; Shamay-Tsoory, Simone G

    2015-01-01

    The space between people, or 'interpersonal distance', creates and defines the dynamics of social interactions and is a salient cue signaling responsiveness and feeling comfortable. This distance is implicit yet clearly felt, especially if someone stands closer or farther away than expected. Increasing evidence suggests that Oxytocin (OT) serves as a social hormone in humans, and that one of its roles may be to alter the perceptual salience of social cues. Considering that empathic ability may shape the way individuals process social stimuli, we predicted that OT will differentially affect preferred interpersonal distance depending on individual differences in empathy. Participants took part in two interpersonal distance experiments: In the first, they had to stop a (computer visualized) protagonist when feeling most comfortable; in the second, they were asked to choose the room in which they would later discuss intimate topics with another. Both experiments revealed an interaction between the effect of OT and empathy level. Among highly empathic individuals, OT promoted the choice of closer interpersonal distances. Yet, OT had an opposite effect on individuals with low empathic traits. We conclude that the enhancement of social cues following OT administration may have opposite effects on individuals with different empathic abilities.

  10. OT promotes closer interpersonal distance among highly empathic individuals

    PubMed Central

    Mankuta, David; Shamay-Tsoory, Simone G.

    2015-01-01

    The space between people, or ‘interpersonal distance’, creates and defines the dynamics of social interactions and is a salient cue signaling responsiveness and feeling comfortable. This distance is implicit yet clearly felt, especially if someone stands closer or farther away than expected. Increasing evidence suggests that Oxytocin (OT) serves as a social hormone in humans, and that one of its roles may be to alter the perceptual salience of social cues. Considering that empathic ability may shape the way individuals process social stimuli, we predicted that OT will differentially affect preferred interpersonal distance depending on individual differences in empathy. Participants took part in two interpersonal distance experiments: In the first, they had to stop a (computer visualized) protagonist when feeling most comfortable; in the second, they were asked to choose the room in which they would later discuss intimate topics with another. Both experiments revealed an interaction between the effect of OT and empathy level. Among highly empathic individuals, OT promoted the choice of closer interpersonal distances. Yet, OT had an opposite effect on individuals with low empathic traits. We conclude that the enhancement of social cues following OT administration may have opposite effects on individuals with different empathic abilities. PMID:24509491

  11. A new assessment method of outdoor tobacco smoke (OTS) exposure

    NASA Astrophysics Data System (ADS)

    Cho, Hyeri; Lee, Kiyoung

    2014-04-01

    Outdoor tobacco smoke (OTS) is concerned due to potential health effects. An assessment method of OTS exposure is needed to determine effects of OTS and validate outdoor smoking policies. The objective of this study was to develop a new method to assess OTS exposure. This study was conducted at 100 bus stops including 50 centerline bus stops and 50 roadside bus stops in Seoul, Korea. Using real-time aerosol monitor, PM2.5 was measured for 30 min at each bus stop in two seasons. ‘Peak analysis' method was developed to assess short term PM2.5 exposure by OTS. The 30-min average PM2.5 exposure at each bus stop was associated with season and bus stop location but not smoking activity. The PM2.5 peak occurrence rate by the peak analysis method was significantly associated with season, bus stop location, observed smoking occurrence, and the number of buses servicing a route. The PM2.5 peak concentration was significantly associated with season, smoking occurrence, and the number of buses servicing a route. When a smoker was standing still at the bus stop, magnitude of peak concentrations were significantly higher than when the smoker walking-through the bus stop. People were exposed to high short-term PM2.5 peak levels at bus stops, and the magnitude of peak concentrations were highest when a smoker was located close to the monitor. The magnitude of peak concentration was a good indicator helped distinguish nearby OTS exposure. Further research using ‘peak analysis' is needed to measure smoking-related exposure to PM2.5 in other outdoor locations.

  12. Counterpart of MASTER OT J084140.94+722732.6

    NASA Astrophysics Data System (ADS)

    Nesci, Roberto

    2016-02-01

    Following the ATel #8725 by Balanutsa et al. about MASTER OT J084140.94+722732.6, I made aperture photometry on all the Palomar survey plates (12) available from the MAST archive to get an indication of the star color.

  13. Recent optical activity of the blazar OT 355

    NASA Astrophysics Data System (ADS)

    Bachev, R.; Kurtenkov, A.; Nikolov, Y.; Spassov, B.; Boeva, S.; Latev, G.; Dimitrova, R. V. Munoz

    2017-06-01

    The Flat Spectrum Radio Quasar OT 355 (also known as 7C 173240.70+385949.00, z=0.975) was typically observed to be in the optical between 16th and 21th magnitude (CRTS, http://nesssi.cacr.caltech.edu/catalina/20011332/113321380764100137p.html).

  14. Favorable outcome in open globe injuries with low OTS score.

    PubMed

    Cillino, Giovanni; Ferraro, Lucia; Casuccio, Alessandra; Cillino Salvatore

    2014-09-01

    Open globe eye injuries can have profound social and economic consequences. Here, we describe two cases of war and outdoor activity open globe eye injury where, despite a low OTS score, current microsurgical technology allowed for a favorable outcome. A 33-year-old Libyan soldier had been treated for an open-globe grenade blast trauma to his left eye, which showed light perception and OTS score 2. He had undergone a lensectomy and PPV with silicone oil tamponade. Surgical treatment included scleral buckling, cornea trephination, temporary Eckardt keratoprosthesis, PPV revision, intraocular lens (IOL) implantation, and corneal grafting. Six months later, his VA was improved to 20/70. CASE REPORT 2: A 35-year-old man presented with a corneal laceration in his left eye from a meat skewer, with marked hypotony and LP. After primary corneal wound closure, B-scan ultrasonography revealed massive vitreous hemorrhage (OTS score 2). The patient underwent open cataract extraction with IOL implantation, 23 gauge PPV, laser photocoagulation of the retinochoroidal laceration, and a gas tamponade. After three weeks, the patient underwent a 2nd 23G PPV due to a fibrinous reaction. Six month later, the patients exhibited 20/25 VA. These cases confirm that even for patients with a low OTS and poor visual prognosis, an up-to-date surgery protocol may achieve visual results adequate for leading an autonomous daily life.

  15. MASTER: PSN in bright PGC630422 and OTs

    NASA Astrophysics Data System (ADS)

    Balanutsa, P.; Shumkov, V.; Lipunov, V.; Podesta, R.; Podesta, F.; Lopez, C.; Levato, H.; Saffe, C.; Rebolo, R.; Serra-Ricart, M.; Tlatov, A.; Senik, V.; Gorbovskoy, E.; Tiurina, N.; Kornilov, V.; Gress, O.; Kuznetsov, A.; Chazov, V.; Vladimirov, V.; Vlasenko, D.; Zimnukhov, D.; Gorbunov, I.; Pogrosheva, T.; Krylov, A.; Gabovich, A.

    2017-09-01

    MASTER-OAFA (Argentina) auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 23h 30m 54.7s -36d 57m 27.8s on 2017-08-31 07:40:58.398UT.

  16. 12 CFR 563b.115 - How will OTS review my business plan?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... FROM MUTUAL TO STOCK FORM Standard Conversions Prior to Conversion § 563b.115 How will OTS review my... with the Regional Office. OTS may request additional information, if necessary, to support its...

  17. Software OT&E Guidelines. Volume 1. Software Test Manager’s Handbook

    DTIC Science & Technology

    1981-02-01

    CLASSIFICATION OF THIS PAGE( W ~h Data Xntetd) Blk 20 cont’d. (AFTECP 800-4); 5. Software Support Facility Evaluation Tools User’s Handbook (AFTECP 800...description of the AFTEC approach to OT&E of software. The document is not directive, but rather a reference document for planning OT&E. It contains...Critical Design Review (CDR) ........... .... 39 M. AFTEC Produced Publications ............... ... 40 1. OT&E Approach . ..... .......... 41 2. OT&E

  18. 75 FR 63895 - Open Meeting of the OTS Minority Depository Institutions Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-18

    ... Office of Thrift Supervision Open Meeting of the OTS Minority Depository Institutions Advisory Committee... OTS Minority Depository Institutions Advisory Committee (MDIAC) will convene a meeting on Wednesday.... SUPPLEMENTARY INFORMATION: By this notice, the Office of Thrift Supervision is announcing that the OTS...

  19. 75 FR 38188 - Closed Meeting of the OTS Mutual Savings Association Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-01

    ... Office of Thrift Supervision Closed Meeting of the OTS Mutual Savings Association Advisory Committee.... SUMMARY: The OTS Mutual Savings Associations Advisory Committee (MSAAC) will convene a meeting on... the OTS Mutual Savings Association Advisory Committee will convene a closed meeting on Wednesday, July...

  20. 12 CFR 563b.115 - How will OTS review my business plan?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false How will OTS review my business plan? 563b.115... business plan? (a) OTS will review your business plan to determine that it demonstrates a safe and sound... will be determinative. OTS will review every case on its merits. (b) You must file your business...

  1. Teaching the Moving Child: OT Insights That Will Transform Your K-3 Classroom

    ERIC Educational Resources Information Center

    Berkey, Sybil M.

    2009-01-01

    Because sensorimotor and environmental factors have a profound effect on children's learning, every teacher should know how to weave strategies from occupational therapy (OT) into their everyday instruction. This is the guidebook K-3 teachers need to "think like an OT"--and form effective partnerships with OTs in their schools--so all students can…

  2. 12 CFR 555.300 - Must I inform OTS before I use electronic means or facilities?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Must I inform OTS before I use electronic means... I inform OTS before I use electronic means or facilities? (a) General. A savings association (“you”) are not required to inform OTS before you use electronic means or facilities, except as provided in...

  3. Teaching the Moving Child: OT Insights That Will Transform Your K-3 Classroom

    ERIC Educational Resources Information Center

    Berkey, Sybil M.

    2009-01-01

    Because sensorimotor and environmental factors have a profound effect on children's learning, every teacher should know how to weave strategies from occupational therapy (OT) into their everyday instruction. This is the guidebook K-3 teachers need to "think like an OT"--and form effective partnerships with OTs in their schools--so all students can…

  4. Antimicrobial effects of novel peptides cOT2 and sOT2 derived from Crocodylus siamensis and Pelodiscus sinensis ovotransferrins.

    PubMed

    Prajanban, Bung-On; Jangpromma, Nisachon; Araki, Tomohiro; Klaynongsruang, Sompong

    2017-05-01

    In light of the increasing threat of bacterial drug resistance to human health on a global scale, research and development of antimicrobial peptides as a novel class of potent antibiotics has gained considerable attention. The present study focuses on the structural evaluation and membrane interaction of two new cationic antimicrobial peptides, cOT2 and sOT2, derived from Siamese crocodile (Crocodylus siamensis) and Chinese softshell turtle (Pelodiscus sinensis) ovotransferrins. Here, cOT1 (+3) and sOT1 (+3) were derived from reptile ovotransferrins by chromatographic purification and characterized by mass spectrometry and N-terminal sequencing analysis. In order to increase the antimicrobial efficacy, two novel peptides, cOT2 (+6) and sOT2 (+5), were designed and synthesized as "naturally-engineered" by primary amino acid sequence extension of cOT1 and sOT1, respectively. These rational designs of modified peptides were assayed in term of antimicrobial activity. These peptides display strong antimicrobial activity against several bacterial strains, e.g. Vibrio cholerae, Bacillus megaterium, and Bacillus pumilus TISTR 905, with MICs of 7-16.1μM. In terms of structural conformation in mimic environments, CD spectroscopic analysis of the secondary peptides structure features revealed fairly the similarity on α-helical content with magainin II. Hence, the modes of actions have been speculated as toroidal and carpet model. Furthermore, the disruption of intact bacterial cells induced by cOT2 and sOT2 was investigated by SEM and AFM. The results provided evidence that cOT2 and sOT2 have the potential to cause different morphological changes of bacterial cells and that these effects can be enhanced by increasing the peptide concentration. Copyright © 2017 Elsevier B.V. All rights reserved.

  5. In-orbit performance of the OTS-2 communication antennas

    NASA Astrophysics Data System (ADS)

    Brain, D. J.; Haworth, D. P.; McEwan, N. J.

    The results of the first attempt to make a complete characterization of a complex antenna farm 'in orbit' are analyzed. The satellite is OTS with six antennas, all dual polarized and working at 11 or 14 GHz; the measurements are carried out as part of the European Space Agency's in-orbit tests of OTS. The basic technique involves depointing the satellite bodily through a raster scan + or - 2 deg square and inferring antenna patterns from the signal levels recorded at various ground stations. It is found that fairly subtle in-orbit effects can be detected, provided sufficient effort is put into the data processing. It is recommened that if further tests of this kind are to be attempted, particular attention is paid to the accurate absolute calibration, diurnal stability and dynamic range - at least 30 and preferably 40 dB - of the ground station receivers.

  6. Formose reaction accelerated in aerosol-OT reverse micelles

    PubMed Central

    Masaoka, Makoto; Michitaka, Tomohiro

    2016-01-01

    The formose reaction in reverse micelles of aerosol-OT (AOT), triton X-100 (TX), and hexadecyltrimethylammonium bromide (CTAB) was investigated. Time–conversion data have indicated that the interfacial water layer of AOT reverse micelles is a medium that accelerates formation of glycolaldehyde in the formose reaction. The 13C NMR spectra for the products of the formose reaction using formaldehyde-13C as starting material are indicative of the formation of ethylene glycol as a major product. PMID:28144336

  7. MASTER OT J125532.84-050442.8 is Himalia

    NASA Astrophysics Data System (ADS)

    Denisenko, D.

    2016-11-01

    Bright optical transient MASTER OT J125532.84-050442.8 reported by Shumkov et al., ATel #9766 is the satellite of Jupiter Himalia. Here is the ephemeris of Jupiter VI for observatory code [Z22] around the reported time of observations by MASTER-IAC (2016-11-17.26843 UT = 06:26:32 UT) generated using MPC Natural Satellites Ephemeris Service: Date UT R.A. (J2000) Decl.

  8. Optimization of OT-MACH Filter Generation for Target Recognition

    NASA Technical Reports Server (NTRS)

    Johnson, Oliver C.; Edens, Weston; Lu, Thomas T.; Chao, Tien-Hsin

    2009-01-01

    An automatic Optimum Trade-off Maximum Average Correlation Height (OT-MACH) filter generator for use in a gray-scale optical correlator (GOC) has been developed for improved target detection at JPL. While the OT-MACH filter has been shown to be an optimal filter for target detection, actually solving for the optimum is too computationally intensive for multiple targets. Instead, an adaptive step gradient descent method was tested to iteratively optimize the three OT-MACH parameters, alpha, beta, and gamma. The feedback for the gradient descent method was a composite of the performance measures, correlation peak height and peak to side lobe ratio. The automated method generated and tested multiple filters in order to approach the optimal filter quicker and more reliably than the current manual method. Initial usage and testing has shown preliminary success at finding an approximation of the optimal filter, in terms of alpha, beta, gamma values. This corresponded to a substantial improvement in detection performance where the true positive rate increased for the same average false positives per image.

  9. Fixed ground antenna radome (FGAR) type 1/3 OT&E integrations and OT&E operational

    NASA Astrophysics Data System (ADS)

    Baker, Leonard H.; Sedgwick, Harold G.

    1995-05-01

    This test report documents the Operational Test and Evaluation (OT&E) Integration and OT&E Operational testing performed on the Type I/Ill, Fixed Ground Antenna Radome (FGAR). The Type I/Ill FGAR is used with the Air Route Surveillance Radar (ARSR)) -1/2 and AN/FPS military radars. The testing was performed at the Federal Aviation Administration (FAA) Technical Center's Elwood En Route Beacon Test Facility (ERBTF) and the Northwest Mountain Region's Trinidad En Route Radar Facility (TAD), Colorado. The testing included: (1) characterization of the primary and secondary radar's electromagnetic performance; (2) human factors; (3) physical characteristics; and (4) physical performance. The electromagnetic performance testing showed no degradation of the primary or secondary radars; there were no human factor problems found; and only minor problems were identified during the physical characteristics and physical performance tests. The testing determined that the FGAR meets the Operational Suitability and Operational Effectiveness requirements of the FAA.

  10. Construct and ecological validity of the Occupational Therapy Adult Perceptual Screening Test (OT-APST).

    PubMed

    Cooke, Deirdre M; McKenna, Kryss; Fleming, Jennifer; Darnell, Ross

    2006-03-01

    This paper reports on the construct validity (scale design and convergent validity) and ecological validity of the Occupational Therapy Adult Perceptual Screening Test (OT-APST). The performance of 208 participants following stroke on the OT-APST and a reference tool (either the Loewenstein Occupational Therapy Cognitive Assessment (LOTCA) or the LOTCA-Geriatric version (LOTCA-G)) was compared. The OT-APST performance of the stroke sample was compared with a healthy normative sample (n = 356). The relationship between the OT-APST performance and the Functional Independence Measure (FIM) score of the participants following stroke was also examined. Factor analysis and internal consistency results supported the scale design of the OT-APST. Significant correlations between the performance of the participants following stroke on the OT-APST and the reference tool supported the convergent validity of the OT-APST. The ability of the OT-APST to separate the two participant groups provided further evidence of its construct validity. Significant correlations between OT-APST and FIM scores supported the ecological validity of this tool. This study shows that the OT-APST is an ecologically valid tool with demonstrated construct validity in the assessment of visual perception.

  11. OTS Selective Bibliography. High Temperature Metallurgy and Heat Resistant Alloys

    DTIC Science & Technology

    1961-02-01

    Order from OTS at 75 cents PB 151083 thermite reactions were studies with regard to throt- tling materials (alumina versus kaolin , EPK), binders SELECTED...THERMODYNAMICS OF MOLTEN ALLOYS (Dilute solutions of metals - bibliography), by Goodwin and Ayton. sulphur in liquid tin and lead. Sn-Cu-S, Sn-Ag-S...1958, no. 6, p. 41-47. sulphur dioxide), by Makolkin. 1959. llp. Order as HB-4253 from HB at $4.90 59-14611 Trans. of Zhurnal Prikladnoy Khimii (USSR

  12. MASTER-SAAO: contradictory SN and flaring OT

    NASA Astrophysics Data System (ADS)

    Balanutsa, P.; Lipunov, V.; Buckley, D.; Gorbovskoy, E.; Tiurina, N.; Kuznetsov, A.; Kornilov, V.; Gress, O.; Pogrosheva, T.; Shumkov, V.; Vladimirov, V.; Vlasenko, D.; Kuvshinov, D.; Gabovich, A.

    2017-07-01

    MASTER-SAAO auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 03h 42m 50.70s , -01d 52m 28s.7 on 2017-07-01.1753UT with unfiltered (6 images), that contradicts to Ia type detected in ATEL #10240 , ATEL #10225 for ATLAS17dcl ( http://www.supernova.thistlethwaites.com/sn2017/sndate.html ). It is in 8.4"W,20"S of PGC135685 with Btc=15.13, Vgsr=2773 http://leda.univ-lyon1.fr/ledacat.cgi?PGC135685 Spectral observations are required.

  13. Military (OTS ETE) Specification for the Multimeter, Digital,

    DTIC Science & Technology

    1979-12-01

    DAA907-78-A-6606 UNCLASSIFIED 157 -Ol 2O8 NL * !Ihh~HhhhhMonsonfllf LEYE 042 am 0 MILITARY (OTS ETEI SPECIFICATION OFOR THE 0. (MULTIMETER, DIGITAL " . k...Classification. ’The equipment defined by this specification shall be Type II, Class 5, Style E, Color R per MIL-T-28800 and- heiirzin with the convertible...Class 5, Style E, Color R, design and construction requirements of MIL-T-28800 with the convertible/rack- mountable capability. 3.4.1 First article

  14. Complex architecture and regulated expression of the Sox2ot locus during vertebrate development

    PubMed Central

    Amaral, Paulo P.; Neyt, Christine; Wilkins, Simon J.; Askarian-Amiri, Marjan E.; Sunkin, Susan M.; Perkins, Andrew C.; Mattick, John S.

    2009-01-01

    The Sox2 gene is a key regulator of pluripotency embedded within an intron of a long noncoding RNA (ncRNA), termed Sox2 overlapping transcript (Sox2ot), which is transcribed in the same orientation. However, this ncRNA remains uncharacterized. Here we show that Sox2ot has multiple transcription start sites associated with genomic features that indicate regulated expression, including highly conserved elements (HCEs) and chromatin marks characteristic of gene promoters. To identify biological processes in which Sox2ot may be involved, we analyzed its expression in several developmental systems, compared to expression of Sox2. We show that Sox2ot is a stable transcript expressed in mouse embryonic stem cells, which, like Sox2, is down-regulated upon induction of embryoid body (EB) differentiation. However, in contrast to Sox2, Sox2ot is up-regulated during EB mesoderm-lineage differentiation. In adult mouse, Sox2ot isoforms were detected in tissues where Sox2 is expressed, as well as in different tissues, supporting independent regulation of expression of the ncRNA. Sox2dot, an isoform of Sox2ot transcribed from a distal HCE located >500 kb upstream of Sox2, was detected exclusively in the mouse brain, with enrichment in regions of adult neurogenesis. In addition, Sox2ot isoforms are transcribed from HCEs upstream of Sox2 in other vertebrates, including in several regions of the human brain. We also show that Sox2ot is dynamically regulated during chicken and zebrafish embryogenesis, consistently associated with central nervous system structures. These observations provide insight into the structure and regulation of the Sox2ot gene, and suggest conserved roles for Sox2ot orthologs during vertebrate development. PMID:19767420

  15. Radiation Susceptibility Assessment of Off the Shelf (OTS) Hardware

    NASA Technical Reports Server (NTRS)

    Culpepper, William X.; Nicholson, Leonard L. (Technical Monitor)

    2000-01-01

    The reduction in budgets, shortening of schedules and necessity of flying near state of the art technology have forced projects and designers to utilize not only modern, non-space rated EEE parts but also OTS boards, subassemblies and systems. New instrumentation, communications, portable computers and navigation systems for the International Space Station, Space Shuttle, and Crew Return Vehicle are examples of the realization of this paradigm change at the Johnson Space Center. Because of this change, there has been a shift in the radiation assessment methodology from individual part testing using low energy heavy ions to board and box level testing using high-energy particle beams. Highlights of several years of board and system level testing are presented along with lessons learned, present areas of concern, insights into test costs, and future challenges.

  16. Monitoring the activity of the Be star OT Geminorum

    NASA Astrophysics Data System (ADS)

    Arellano Ferro, A.; Sareyan, J. P.; Avila, J. J.; Gonzalez, F.; Dumont, M.; Geos

    1998-02-01

    Observations obtained in 1995-1996 of the Be star OT Geminorum are reported and show that in october 1995 the star reached a very active phase with large variations around a bright plateau, a phase of activity we have also distinguished in previous observations dating from 1960. The time scales involved are discussed and suggest that the violent variations of the activity propagate very quickly on the whole surface of the star or on a huge portion of it. No likely pulsation periods were found. The assumption that the detected activity is due to the effects of an hypothetical companion leads to conclude that such companion could not be detected by the present interferometric techniques. Partly based on observations obtained at the La Luz Observatory of the University of Guanajuato, Mexico.

  17. 12 CFR 502.60 - When will OTS adjust, add, waive, or eliminate a fee?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false When will OTS adjust, add, waive, or eliminate... TREASURY ASSESSMENTS AND FEES Fees § 502.60 When will OTS adjust, add, waive, or eliminate a fee? Under... eliminate a fee. For example, the Director may: (a) Reduce any fee to adjust for any inequities...

  18. 12 CFR 502.60 - When will OTS adjust, add, waive, or eliminate a fee?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 5 2011-01-01 2011-01-01 false When will OTS adjust, add, waive, or eliminate... TREASURY ASSESSMENTS AND FEES Fees § 502.60 When will OTS adjust, add, waive, or eliminate a fee? Under... eliminate a fee. For example, the Director may: (a) Reduce any fee to adjust for any inequities...

  19. 12 CFR 502.60 - When will OTS adjust, add, waive, or eliminate a fee?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 6 2012-01-01 2012-01-01 false When will OTS adjust, add, waive, or eliminate... TREASURY ASSESSMENTS AND FEES Fees § 502.60 When will OTS adjust, add, waive, or eliminate a fee? Under... eliminate a fee. For example, the Director may: (a) Reduce any fee to adjust for any inequities...

  20. 12 CFR 502.60 - When will OTS adjust, add, waive, or eliminate a fee?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 6 2014-01-01 2012-01-01 true When will OTS adjust, add, waive, or eliminate a... ASSESSMENTS AND FEES Fees § 502.60 When will OTS adjust, add, waive, or eliminate a fee? Under unusual circumstances, the Director may deem it necessary or appropriate to adjust, add, waive, or eliminate a fee. For...

  1. 12 CFR 502.60 - When will OTS adjust, add, waive, or eliminate a fee?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 6 2013-01-01 2012-01-01 true When will OTS adjust, add, waive, or eliminate a... ASSESSMENTS AND FEES Fees § 502.60 When will OTS adjust, add, waive, or eliminate a fee? Under unusual circumstances, the Director may deem it necessary or appropriate to adjust, add, waive, or eliminate a fee. For...

  2. 12 CFR 516.250 - Will OTS require me to publish a new public notice?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 5 2011-01-01 2011-01-01 false Will OTS require me to publish a new public... publish a new public notice? (a) If your application was subject to a publication requirement, OTS may require you to publish a new public notice of your application if: (1) You submitted a revision to the...

  3. 12 CFR 516.250 - Will OTS require me to publish a new public notice?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Will OTS require me to publish a new public... publish a new public notice? (a) If your application was subject to a publication requirement, OTS may require you to publish a new public notice of your application if: (1) You submitted a revision to the...

  4. MASTER: high amplitude (>6.8m) optical transient and new OT

    NASA Astrophysics Data System (ADS)

    Gress, O.; Pogrosheva, T.; Lipunov, V.; Gorbovskoy, E.; Tiurina, N.; Balanutsa, P.; Kuznetsov, A.; Kornilov, V.; Chazov, V.; Vladimirov, V.; Shumkov, V.; Kuvshinov, D.; Ivanov, K.; Budnev, N.; Tlatov, A.; Senik, V.

    2017-02-01

    MASTER-Tunka auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 19h 12m 48.12s +37d 49m 34.6s on 2017-01-31.86338 UT. The OT unfiltered magnitude is (limit 18.4m).

  5. 12 CFR 563b.300 - What must happen before OTS declares my offering circular effective?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 5 2011-01-01 2011-01-01 false What must happen before OTS declares my offering circular effective? 563b.300 Section 563b.300 Banks and Banking OFFICE OF THRIFT SUPERVISION... § 563b.300 What must happen before OTS declares my offering circular effective? (a) You must prepare...

  6. 75 FR 61572 - Open Meeting of the OTS Mutual Savings Association Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-05

    ... Office of Thrift Supervision Open Meeting of the OTS Mutual Savings Association Advisory Committee AGENCY... Savings Associations Advisory Committee (MSAAC) will convene a meeting on Wednesday, October 20, 2010... the OTS Mutual Savings Association Advisory Committee will convene a meeting on Wednesday, October 20...

  7. 75 FR 24775 - Open Meeting of the OTS Mutual Savings Association Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-05

    ... Office of Thrift Supervision Open Meeting of the OTS Mutual Savings Association Advisory Committee AGENCY... Savings Associations Advisory Committee (MSAAC) will convene a telephonic meeting on Friday, May 21, 2010..., the Office of Thrift Supervision is announcing that the OTS Mutual Savings Association Advisory...

  8. 12 CFR 563.146 - Will the OTS permit my capital distribution?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... under 12 U.S.C. 1831o(d)(1)(B). (b) Your proposed capital distribution raises safety or soundness... 12 Banks and Banking 6 2012-01-01 2012-01-01 false Will the OTS permit my capital distribution... distribution? The OTS will review your notice or application under the review procedures in 12 CFR part...

  9. MASTER-SAAO, MASTER-IAC: new OT, dwarf nova outburst and UVCet flare

    NASA Astrophysics Data System (ADS)

    Vladimirov, V.; Balanutsa, P.; Gress, O.; Lipunov, V.; Buckley, D.; Rebolo, R.; Serra-Ricart, M.; Gorbovskoy, E.; Tiurina, N.; Shumkov, V.; Pogrosheva, T.; Kuznetsov, A.; Kornilov, V.; Chazov, V.; Gorbunov, I.; Podesta, R.; Levato, H.; Lopez, C.; Podesta, F.; Saffe, C.; Gabovich, A.

    2017-05-01

    MASTER-SAAO auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 10h 36m 25.83s -36d 02m 28.3s on 2017-05-22.75738 UT. The OT unfiltered magnitude is 18.7m (mlim=19.7).

  10. MASTER-Kislovodsk: bright OT (PSN or CV, ampl>5.2m)

    NASA Astrophysics Data System (ADS)

    Kuznetsov, N.; Shumkov, V.; Lipunov, V.; Tlatov, A.; Rebolo, R.; Serra-Ricart, M.; Senik, V.; Gorbovskoy, E.; Tiurina, N.; Balanutsa, P.; Kuznetsov, A.; Kornilov, V.; Vladimirov, V.; Vlasenko, D.; Dormidontov, D.; Parkhomenko, A.; Gress, O.; Ivanov, K.; Budnev, N.

    2016-10-01

    MASTER-Kislovodsk auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 10h 06m 29.13s +22d 26m 43.8s with unfiltered m_OT=16.8m on 2016-10-09 00:56:53.746UT.

  11. MASTER: QSO flare (5BZQ J1312-0424) and OTs

    NASA Astrophysics Data System (ADS)

    Balanutsa, P.; Shumkov, V.; Pogrosheva, T.; Popova, E.; Lipunov, V.; Podesta, R.; Levato, H.; Lopez, C.; Podesta, F.; Tlatov, A.; Gorbovskoy, E.; Tiurina, N.; Kuznetsov, A.; Kornilov, V.; Vladimirov, V.; Ivanov, O. Gress K.; Chazov, V.

    2016-11-01

    MASTER-Kislovodsk auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 13h 12m 50.91s -04d 24m 49.1s on 2016-11-20.11222 UT. The OT unfiltered magnitude is (mlim=18.2m).

  12. MASTER-Tunka: bright 6mag ampl dwarf nova outburst and OT from MASTER-SAAO

    NASA Astrophysics Data System (ADS)

    Gress, O.; Balanutsa, P.; Lipunov, V.; Buckley, D.; Potter, S.; Budnev, N.; Ivanov, K.; Tiurina, N.; Gorbovskoy, E.; Kuznetsov, A.; Kornilov, V.; Vladimirov, V.; Chazov, V.; Kuvshinov, D.

    2016-11-01

    MASTER-Tunka auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 07h 37m 04.36s +25d 00m 54.5s on 2016-11-09.74453 UT. The OT unfiltered magnitude is (mlim=18.4m).

  13. MASTER-IAC: bright OT with ampltude more then 6.3mag

    NASA Astrophysics Data System (ADS)

    Shumkov, V.; Lipunov, V.; Rebolo, R.; Serra-Ricart, M.; Gorbovskoy, E.; Tiurina, N.; Kuznetsov, A.; Vladimirov, V.; Balanutsa, P.; Kuvshinov, D.; Kornilov, V.; Chazov, V.

    2016-11-01

    MASTER-IAC auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 12h 55m 32.84s -05d 04m 42.8s on 2016-11-17.26843 UT. The OT unfiltered magnitude is 15.7m (limit 17.5m).

  14. The 1000-th MASTER detection and SALT limit: Fast Doublet OT

    NASA Astrophysics Data System (ADS)

    Balanutsa, P.; Lipunov, V.; Gorbovskoy, E.; Buckley, D.; Kniazev, A.; Tiurina, N.; Kornilov, V.; Samus, N.; Kuznetsov, A.; Vlasenko, D.; Gorbunov, I.; Popova, E.; Vladimirov, V.; Shumkov, V.; Potter, S.; Kotze, M.; Gress, O.; Budnev, N.; Yazev, S.; Ivanov, K.; Tlatov, A.; Senik, V.; Dormidontov, D.; Parhomenko, A. V.; Yurkov, V.; Sergienko, Yu.; Gabovich, A.; Sinyakov, E.; Rebolo, R.; Serra-Ricart, M.; Lodieu, N.; Israelian, G.; Suarez-Andres, L.; Levato, Hugo; Astronomicas, Carlos Saffe Instituto de Ciencias; Espacio, de la Tierra y. del; Podesta, Ricardo; Mallamaci, Claudio; Lopez, Carlos; Podesta, Federico

    2015-12-01

    MASTER-SAAO (Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 349171) discovered the 1000th OT source at (RA, Dec) = 05h 10m 14.58s -29d 09m 00.6s on 2015-12-16.97115 UT. The OT unfiltered magnitude is 18.8m (the limit is 20.4m).

  15. 12 CFR 563b.295 - Will OTS require me to re-solicit proxies?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Will OTS require me to re-solicit proxies? 563b.295 Section 563b.295 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY... to re-solicit proxies? If you amend your application for conversion, OTS may require you to...

  16. Criterion validity of the Occupational Therapy Adult Perceptual Screening Test (OT-APST).

    PubMed

    Cooke, Deirdre M; McKenna, Kryss; Fleming, Jennifer; Darnell, Ross

    2006-03-01

    This paper reports on the criterion validity of the Occupational Therapy Adult Perceptual Screening Test (OT-APST) including concurrent criterion validity and its sensitivity and specificity. The performance of 208 people following stroke on the OT-APST and a reference tool (either the Loewenstein Occupational Therapy Cognitive Assessment (LOTCA) or the LOTCA--Geriatric version (LOTCA-G)) was compared. The OT-APST subscale scores and performance outcome (intact or impaired) on related subscales of the reference tool was analyzed to evaluate the concurrent criterion validity of the OT-APST and its sensitivity and specificity at selected cut-off scores. Significant correlations were found between participants' performance (intact or impaired) on the reference tool and scores on the OT-APST. The sensitivity and specificity of the OT-APST were analyzed at selected cut-off scores to explore the validity of decisions based on OT-APST performance when compared with the reference tool. This study shows that the OT-APST is a tool with demonstrated concurrent criterion validity for the assessment of visual perception.

  17. Swift observations of MASTER OT J120451.50+265946.6 (Type Ib SN)

    NASA Astrophysics Data System (ADS)

    Margutti, Raffaella; Brown, Peter J.; Kamble, Atish; Milisavljevic, Dan; Parrent, Jerod; Soderberg, Alicia M.

    2014-11-01

    MASTER OT J120451.50+265946.6 (Atel #6634) has been recently classified as a Type Ib SN a few weeks after maximum light (Atel #6639, #6640, #6641). MASTER OT J120451.50+265946.6 exploded in NGC 4080 (distance of 15 Mpc, Karachentsev et al., 2013).

  18. 12 CFR 502.15 - How does OTS determine my size component?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 6 2013-01-01 2012-01-01 true How does OTS determine my size component? 502.15... size component? (a) Chart. If you are a savings association, OTS uses the following chart to calculate your size component: If your total assets are: . . . Over—* Column A But not over— Column B Your...

  19. 12 CFR 502.15 - How does OTS determine my size component?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 6 2014-01-01 2012-01-01 true How does OTS determine my size component? 502.15... size component? (a) Chart. If you are a savings association, OTS uses the following chart to calculate your size component: If your total assets are: . . . Over—* Column A But not over— Column B Your...

  20. 12 CFR 502.15 - How does OTS determine my size component?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 5 2011-01-01 2011-01-01 false How does OTS determine my size component? 502... determine my size component? (a) Chart. If you are a savings association, OTS uses the following chart to calculate your size component: If your total assets are: . . . Over—* Column A But not over— Column B...

  1. 12 CFR 563b.300 - What must happen before OTS declares my offering circular effective?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 6 2014-01-01 2012-01-01 true What must happen before OTS declares my offering circular effective? 563b.300 Section 563b.300 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF... What must happen before OTS declares my offering circular effective? (a) You must prepare and file your...

  2. 12 CFR 563b.300 - What must happen before OTS declares my offering circular effective?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 6 2012-01-01 2012-01-01 false What must happen before OTS declares my offering circular effective? 563b.300 Section 563b.300 Banks and Banking OFFICE OF THRIFT SUPERVISION... § 563b.300 What must happen before OTS declares my offering circular effective? (a) You must prepare and...

  3. 12 CFR 502.25 - How does OTS determine my complexity component?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false How does OTS determine my complexity component... determine my complexity component? If you are a savings association and your portfolio exceeds any of the thresholds in paragraph (a) of this section, OTS will calculate your complexity component according to...

  4. 12 CFR 516.10 - How does OTS compute time periods under this part?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false How does OTS compute time periods under this part? 516.10 Section 516.10 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY APPLICATION PROCESSING PROCEDURES § 516.10 How does OTS compute time periods under this part? In...

  5. Formation of octadecyltrichlorosilane (OTS) self-assembled monolayers on amorphous alumina

    NASA Astrophysics Data System (ADS)

    Kelkar, Sanket S.; Chiavetta, David; Wolden, Colin A.

    2013-10-01

    The kinetics and thermodynamics of octadecyltrichlorosilane (OTS) self-assembled monolayers (SAMs) on vapor deposited alumina were quantified. Ozone cleaning serves to create well-defined hydrophilic surfaces for OTS attachment, and the use of heptane as a solvent enables the formation of high quality SAMs under ambient conditions. The kinetics was characterized as a function of OTS concentration using contact angle goniometry, ellipsometry and Fourier transform infrared (FTIR) spectroscopy. The kinetics of SAM formation and the saturation contact angle (∼100̊) on alumina are comparable to what has been observed for OTS on silicon. The free energy of adsorption with ΔGads values ranged from -7.5 to -5.4 kcal/mol, and the SAMs were stable up to 230 ̊C. The critical surface tension of the OTS monolayer was found to be 21.4 dyne/cm.

  6. 12 CFR 502.28 - How does OTS determine the organizational form component for a savings and loan holding company?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false How does OTS determine the organizational form...-Calculation of Assessments § 502.28 How does OTS determine the organizational form component for a savings and loan holding company? OTS will include an organizational form component if you are a responsible...

  7. 12 CFR 550.70 - Must I obtain OTS approval or file a notice before I exercise fiduciary powers?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... before I exercise fiduciary powers? 550.70 Section 550.70 Banks and Banking OFFICE OF THRIFT SUPERVISION... I obtain OTS approval or file a notice before I exercise fiduciary powers? You should refer to the following chart to determine if you must obtain OTS approval or file a notice with OTS before you...

  8. 12 CFR 550.70 - Must I obtain OTS approval or file a notice before I exercise fiduciary powers?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... before I exercise fiduciary powers? 550.70 Section 550.70 Banks and Banking OFFICE OF THRIFT SUPERVISION... I obtain OTS approval or file a notice before I exercise fiduciary powers? You should refer to the following chart to determine if you must obtain OTS approval or file a notice with OTS before you...

  9. 12 CFR 550.70 - Must I obtain OTS approval or file a notice before I exercise fiduciary powers?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... before I exercise fiduciary powers? 550.70 Section 550.70 Banks and Banking OFFICE OF THRIFT SUPERVISION... I obtain OTS approval or file a notice before I exercise fiduciary powers? You should refer to the following chart to determine if you must obtain OTS approval or file a notice with OTS before you...

  10. 12 CFR 550.70 - Must I obtain OTS approval or file a notice before I exercise fiduciary powers?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... before I exercise fiduciary powers? 550.70 Section 550.70 Banks and Banking OFFICE OF THRIFT SUPERVISION... I obtain OTS approval or file a notice before I exercise fiduciary powers? You should refer to the following chart to determine if you must obtain OTS approval or file a notice with OTS before you...

  11. 12 CFR 550.70 - Must I obtain OTS approval or file a notice before I exercise fiduciary powers?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... before I exercise fiduciary powers? 550.70 Section 550.70 Banks and Banking OFFICE OF THRIFT SUPERVISION... I obtain OTS approval or file a notice before I exercise fiduciary powers? You should refer to the following chart to determine if you must obtain OTS approval or file a notice with OTS before you...

  12. Vibrational energy relaxation of water in Aerosol OT reverse micelle

    NASA Astrophysics Data System (ADS)

    Pang, Yoonsoo; Deak, John; Dlott, Dana

    2005-03-01

    An IR-Raman technique with mid-IR pump and anti-Stokes Raman probe is used to investigate reverse micelle mixture of Aerosol OT, water, and carbon tetrachloride, where polar water phase and nonpolar oil phase is separated by a monolayer of surfactant molecules. Anti-Stokes Raman scattering is only dependent on the population of vibrationally excited states, thus time-dependent population changes of parent/daughter vibrations can be monitored with this technique. Vibrational energy from nanodroplet of water is transferred to the surfactant head group in 1.8 ps and then out to solvent in 10 ps. Vibrational energy directly pumped into the surfactant tail group results in a slower 20-40 ps energy transfer to solvent. This energy transfer cannot be explained by ordinary heat transfer, but the specific vibrational energy relaxation pathway such as sulfonate stretch of surfactant molecules should be used. We can change the water-to-solvent energy transfer rate by adopting different size of reverse micelles or changing pump frequency over the broad OH stretch mode of water due to hydrogen bond network. Water molecules confined in nanometer scale reverse micelles have very different properties from bulk water and we have found many differences between the vibrational dynamics of water in these reverse micelles and those of bulk water.

  13. 12 CFR 555.300 - Must I inform OTS before I use electronic means or facilities?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... transactional web site. A transactional web site is an Internet site that enables users to conduct financial... services. (c) Other procedures. If the OTS Regional Office informs you of any supervisory or compliance...

  14. 12 CFR 555.300 - Must I inform OTS before I use electronic means or facilities?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... transactional web site. A transactional web site is an Internet site that enables users to conduct financial... services. (c) Other procedures. If the OTS Regional Office informs you of any supervisory or compliance...

  15. 12 CFR 563b.200 - What actions may OTS take on my application?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... CONVERSIONS FROM MUTUAL TO STOCK FORM Standard Conversions Ots Review of the Application for Conversion § 563b... methodology, and sufficient support for the conclusions. (5) If the appraisal is based on a capitalization of...

  16. 12 CFR 563b.200 - What actions may OTS take on my application?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... record under part 563e of this chapter and your business plan to determine how you will serve the... that you will serve. (2) OTS may deny your application if your business plan does not demonstrate...

  17. Effects of Hypergravity Exposure on Plasma Oxytocin (OT) Concentrations in Pregnant and Lactating Rat Dams

    NASA Technical Reports Server (NTRS)

    Baer, Lisa A.; Wade, Charles E.; Plaut, Karen; Ronca, April E.; Dalton, Bonnie (Technical Monitor)

    2002-01-01

    From pregnancy to weaning there is a progressive elevation of plasma oxytocin (OT) levels associated with nursing activity, irrespective of litter size. In the present study, we analyzed the effects of continuous 1.5G, 1.75G and 2.0G hypergravity exposure on OT plasma concentration in prepartum (Gestation Day 20) (G20) and lactating (Postnatal day) (P10) rat dams. For this study, litter size was controlled with a yoking procedure established in our lab where individual control litters were yoked-matched to individual hypergravity litters. We reviewed all data at hypergravity irrespective of gravitational level and compared the values with the controls in both G20 (HG, n=15;SC, n=9) and P10 (HG, n=21;SC, n=16). Results showed that over time, we did observe the expected OT increase in both groups. In G20 dams, measurement of OT concentrations showed no significance. However, at P10, measurements of OT concentrations suggest a reduction of about 20% compared to established controls in our laboratory, 0.9+/-0.09 ng/ml for the controls and 0.7+/-0.06 ng/ml for centrifuged animals (p<0.02). These data suggest that exposure to centrifugation may reduce OT levels during lactation. When these plasma samples were obtained, the dams were removed from the litters, and values were not adjusted for the size of the litters. The reduction in OT with centrifugation may reflect a decrease in nursing activity or a decreased responsiveness of the mammary hypothalamic axis. In addition, we have analyzed data on plasma prolactin concentrations and mammary gland development, which may give additional insight to the results of our OT measurements.

  18. Effects of Hypergravity Exposure on Plasma Oxytocin (OT) Concentrations in Pregnant and Lactating Rat Dams

    NASA Technical Reports Server (NTRS)

    Baer, Lisa A.; Wade, Charles E.; Plaut, Karen; Ronca, April E.; Dalton, Bonnie (Technical Monitor)

    2002-01-01

    From pregnancy to weaning there is a progressive elevation of plasma oxytocin (OT) levels associated with nursing activity, irrespective of litter size. In the present study, we analyzed the effects of continuous 1.5G, 1.75G and 2.0G hypergravity exposure on OT plasma concentration in prepartum (Gestation Day 20) (G20) and lactating (Postnatal day) (P10) rat dams. For this study, litter size was controlled with a yoking procedure established in our lab where individual control litters were yoked-matched to individual hypergravity litters. We reviewed all data at hypergravity irrespective of gravitational level and compared the values with the controls in both G20 (HG, n=15;SC, n=9) and P10 (HG, n=21;SC, n=16). Results showed that over time, we did observe the expected OT increase in both groups. In G20 dams, measurement of OT concentrations showed no significance. However, at P10, measurements of OT concentrations suggest a reduction of about 20% compared to established controls in our laboratory, 0.9+/-0.09 ng/ml for the controls and 0.7+/-0.06 ng/ml for centrifuged animals (p<0.02). These data suggest that exposure to centrifugation may reduce OT levels during lactation. When these plasma samples were obtained, the dams were removed from the litters, and values were not adjusted for the size of the litters. The reduction in OT with centrifugation may reflect a decrease in nursing activity or a decreased responsiveness of the mammary hypothalamic axis. In addition, we have analyzed data on plasma prolactin concentrations and mammary gland development, which may give additional insight to the results of our OT measurements.

  19. MASTER discovery: blue bright OT during FERMI 496473540 (GRB160925A) inspection

    NASA Astrophysics Data System (ADS)

    Gress, O.; Lipunov, V.; Buckley, D.; Tiurina, N.; Gorbovskoy, E.; Balanutsa, P.; Kuznetsov, A.; Kornilov, V.; Vladimirov, V.; Shumkov, V.; Pogrosheva, T.; Rebolo Lopez, R.; Serra Ricart, M.; Podesta, R.; Levato, H.; Potter, S.; Lodieu, N.; Saffe, C.; Lopez, C.; Podesta, F.

    2016-09-01

    MASTER-SAAO auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 22h 28m 17.90s -14d 56m 57.4s on 2016-09-25.75053 UT during automatically inspection of Fermi trigger 496473540 ( http://gcn.gsfc.nasa.gov/other/496473540.fermi ). The OT unfiltered magnitude is (limit 19.7m).

  20. OT2_smalhotr_3: Herschel Extreme Lensing Line Observations (HELLO)

    NASA Astrophysics Data System (ADS)

    Malhotra, S.

    2011-09-01

    We request 59.8 hours of Herschel time to observe 20 normal star-forming galaxies in the [CII] 158 micron and [OI] 63 micron lines. These galaxies lie at high redshift (1OT1, 49 high redshift IR luminous galaxies were approved for spectroscopy, but only two so-called normal galaxies were included. This is an imbalance that should be corrected, to balance Herschel's legacy.

  1. Oxytocin (OT) and arginine-vasopressin (AVP) act on OT receptors and not AVP V1a receptors to enhance social recognition in adult Syrian hamsters (Mesocricetus auratus).

    PubMed

    Song, Zhimin; Larkin, Tony E; Malley, Maureen O'; Albers, H Elliott

    2016-05-01

    Social recognition is a fundamental requirement for all forms of social relationships. A majority of studies investigating the neural mechanisms underlying social recognition in rodents have investigated relatively neutral social stimuli such as juveniles or ovariectomized females over short time intervals (e.g., 2h). The present study developed a new testing model to study social recognition among adult males using a potent social stimulus. Flank gland odors are used extensively in social communication in Syrian hamsters and convey important information such as dominance status. We found that the recognition of flank gland odors after a 3min exposure lasted for at least 24h, substantially longer than the recognition of other social cues in rats and mice. Intracerebroventricular injections of OT and AVP prolonged the recognition of flank gland odor for up to 48h. Selective OTR but not V1aR agonists, mimicked these enhancing effects of OT and AVP. Similarly, selective OTR but not V1aR antagonists blocked recognition of the odors after 20min. In contrast, the recognition of non-social stimuli was not blocked by either the OTR or the V1aR antagonists. Our findings suggest both OT and AVP enhance social recognition via acting on OTRs and not V1aRs and that the recognition enhancing effects of OT and AVP are limited to social stimuli.

  2. OmniTread OT-4 serpentine robot: new features and experiments

    NASA Astrophysics Data System (ADS)

    Borenstein, Johann; Hansen, Malik

    2007-04-01

    Serpentine robots are slender, multi-segmented vehicles designed to provide greater mobility than conventional wheeled or tracked robots. Serpentine robots are thus ideally suited for urban search and rescue, military intelligence gathering, and for surveillance and inspection tasks in hazardous and hard-to-reach environments. One such serpentine robot, developed at the University of Michigan, is the "OmniTread OT-4." The OT-4 comprises seven segments, which are linked to each other by 2-degree-of-freedom joints. The OT-4 can climb over obstacles that are much higher than the robot itself, propel itself inside pipes of different diameters, and traverse even the most difficult terrain, such as rocks or the rubble of a collapsed structure. The foremost and unique design characteristic of the OT-4 is the use of pneumatic bellows to actuate the joints. These bellows allow simultaneous control of position and stiffness for each joint. Controllable stiffness is of crucial importance in serpentine robots, which require stiff joints to cross gaps and compliant joints to conform to rough terrain for effective propulsion. Another unique feature of the OmniTread design is the maximal coverage of all four sides with driven tracks. This design makes the robot indifferent to roll-overs, which are happen frequently when the slender bodies of serpentine robots travel over rugged terrain. This paper describes the OmniTread concept as well as its latest technical features, and an extensive Experiment Results Section documents the abilities of the OT-4.

  3. Short-Term H α Line Variations in Classical Be Stars: 59 Cyg and OT Gem

    NASA Astrophysics Data System (ADS)

    Paul, K. T.; Shruthi, S. B.; Subramaniam, Annapurni

    2017-03-01

    We present the optical spectroscopic study of two classical Be stars, 59 Cyg and OT Gem obtained over a period of few months in 2009. We detected a rare triple-peak H α emission phase in 59 Cyg and a rapid decrease in the emission strength of H α in OT Gem, which are used to understand their circumstellar disks. We find that 59 Cyg is likely to be rapid rotator, rotating at a fractional critical rotation of ˜0.80. The radius of the H α emission region for 59 Cyg is estimated to be R d/ R ∗ ˜ 10.0, assuming a Keplerian disk, suggesting that it has a large disk. We classify stars which have shown triple-peaks into two groups and find that the triple-peak emission in 59 Cyg is similar to ζ Tau. OT Gem is found to have a fractional critical rotation of ˜0.30, suggesting that it is either a slow rotator or viewed in low inclination. In OT Gem, we observed a large reduction in the radius of the H α emission region from ˜6.9 to ˜1.7 in a period of three months, along with the reduction in the emission strength. Our observations suggest that the disk is lost from outside to inside during this disk loss phase in OT Gem.

  4. Octadecyltrichlorosilane (OTS)-coated ionic liquid drops: Micro-reactors for homogenous catalytic reactions at designated interfaces.

    PubMed

    Zhang, Xiaoning; Cai, Yuguang

    2012-01-01

    An ionic liquid (IL), 1-butyl-3-methylimidazolium chloride ([Bmim]Cl) can assemble on prefabricated carboxylic acid-terminated chemical patterns on octadecyltrichlorosilane (OTS) film. The chemical pattern controls the position, shape and size of the IL on the surface. After the IL assembly - by incubating IL drops assembled on sample surface in an OTS silane vapor - an OTS layer was coated on the IL drop surface which encapsulated the IL drop. The OTS-coated capsule can exist stably under aqueous solution. The OTS coating protected the IL drops from being instantaneously dissolved by other solutions. We found that a homogenous catalyst (FeCl(3)) dissolved in [Bmim]Cl can be assembled together on the chemical patterns and subsequently encapsulated together with [Bmim]Cl by OTS coating. The pinhole defects within the vapor-coated silane layer provide space for the catalyst inside the capsule and reactants outside the capsule to meet and react. When the OTS-coated capsule containing a FeCl(3)/IL mixture was soaked under H(2)O(2) solution, the Fe(3+) ions catalyzed the decomposition reaction of hydrogen peroxide at the vapor-coated OTS-water interface. Since the shape and position of the interface is defined by the underneath chemical pattern, our findings show that the OTS-coated IL drops assembled on chemical patterns can be used as novel micro-reactors. This allows homogenous catalytic reactions to occur at the designated interfaces.

  5. MASTER OT in HI4Pi marked area during Fermi 519133191 inspection

    NASA Astrophysics Data System (ADS)

    Shumkov, V.; Lipunov, V.; Gorbovskoy, E.; Tiurina, N.; Balanutsa, P.; Kuznetsov, A.; Kornilov, V.; Gress, O.; Pogrosheva, T.; Chazov, V.; Vlasenko, D.; Vladimirov, V.; Gorbunov, I.; Krylov, A.; Kuvshinov, D.; Gabovich, A.

    2017-06-01

    MASTER-Tavrida auto-detection system( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 349171 ) discovered OT source at (RA, Dec) = 14h 40m 27.85s +48d 25m 51.2s on 2017-06-14.80883 UT during Fermi trigger 519133191 inspection (GRBtime=17/06/14 11:39:46.66, NoticeTime with Rer.b.=1.86d is 19:06:22UT, RADec(2000)=14 42 50 +47 30 00). The OT unfiltered magnitude is 17.5m (mlimit 19.6m).

  6. A global outer-rise/outer-trench-slope (OR/OTS) earthquake study

    NASA Astrophysics Data System (ADS)

    Wartman, J. M.; Kita, S.; Kirby, S. H.; Choy, G. L.

    2009-12-01

    Using improved seismic, bathymetric, satellite gravity and other geophysical data, we investigated the seismicity patterns and focal mechanisms of earthquakes in oceanic lithosphere off the trenches of the world that are large enough to be well recorded at teleseismic distances. A number of prominent trends are apparent, some of which have been previously recognized based on more limited data [1], and some of which are largely new [2-5]: (1) The largest events and the highest seismicity rates tend to occur where Mesozoic incoming plates are subducting at high rates (e.g., those in the western Pacific and the Banda segment of Indonesia). The largest events are predominantly shallow normal faulting (SNF) earthquakes. Less common are reverse-faulting (RF) events that tend to be deeper and to be present along with SNF events where nearby seamounts, seamount chains and other volcanic features are subducting [Seno and Yamanaka, 1996]. Blooms of SNF OR/OTS events usually occur just after and seaward of great interplate thrust (IPT) earthquakes but are far less common after smaller IPT events. (2) Plates subducting at slow rates (<20 mm/a) often show sparse OR/OTS seismicity. It is unclear if such low activity is a long-term feature of these systems or is a consequence of the long return times of great IPT earthquakes (e.g., the sparse OR/OTS seismicity before the 26 December 2004 M9.2 Sumatra earthquake and many subsequent OR/OTS events). (3) OR/OTS shocks are generally sparse or absent where incoming plates are very young (<20 Ma) (e.g., Cascadia, southern Mexico, Nankai, and South Shetlands). (4) Subducting plates of intermediate age (20 to about 65 Ma) display a diversity of focal mechanisms and seismicity patterns. In the Philippines, NE Indonesia, and Melanesia, bands of reverse faulting events occur at or near the trench and SNF earthquakes are restricted to OR/OTS sites further from the trench. (5) Clustering of OR/OTS events of all types commonly occurs where

  7. MASTER-OAFA: bright OT with ampl>6.8m

    NASA Astrophysics Data System (ADS)

    Shumkov, V.; Pogrosheva, T.; Lipunov, V.; Podesta, R.; Levato, H.; Gorbovskoy, E.; Tiurina, N.; Balanutsa, P.; Kuznetsov, A.; Kornilov, V.; Gress, O.; Chazov, V.; Vlasenko, D.; Vladimirov, V.; Gorbunov, I.; Krylov, A.; Kuvshinov, D.; Lopez, C.; Podesta, F.; Saffe, C.; Gabovich, A.

    2017-06-01

    MASTER-OAFA auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 19h 03m 59.99s -48d 52m 54.6s on 2017-06-14 05:44:21.777 UT. The OT unfiltered (W=0.2B+0.8R calibrated by thousands USNO-B1 stars) magnitude is 15.2m (mlim=18.1m).

  8. Expression and Developmental Regulation of Oxytocin (OT) and Oxytocin Receptors (OTR) in the Enteric Nervous System (ENS) and Intestinal Epithelium

    PubMed Central

    Welch, Martha G.; Tamir, Hadassah; Gross, Kara J.; Chen, Jason; Anwar, Muhammad; Gershon, Michael D.

    2011-01-01

    Although oxytocin (OT) and oxytocin receptor (OTR) are known for roles in parturition and milk let-down, they are not hypothalamus-restricted. OT is important in nurturing and opposition to stress. Transcripts encoding OT and OTR have been reported in adult human gut, and OT affects intestinal motility. We tested the hypotheses that OT is endogenous to the enteric nervous system (ENS) and that OTR signaling may participate in enteric neurophysiology. Reverse transcriptase polymerase chain reaction confirmed OT and OTR transcripts in adult mouse and rat gut and in precursors of enteric neurons immunoselected from fetal rats. Enteric OT and OTR expression continued through adulthood but was developmentally regulated, peaking at postnatal day 7. Coincidence of the immunoreactivities of OTR and the neural marker Hu was 100% in the P3 and 71% in the adult myenteric plexus, when submucosal neurons were also OTR-immunoreactive. Co-localization with NeuN established that intrinsic primary afferent neurons are OTR-expressing. Because OTR transcripts and protein were detected in the nodose ganglia, OT signaling might also affect extrinsic primary afferent neurons. Although OT immunoreactivity was found only in ~1% of myenteric neurons, extensive OT-immunoreactive varicosities surrounded many others. Villus enterocytes were OTR-immunoreactive through postnatal day 17; however, by postnatal day 19, immunoreactivity waned to become restricted to crypts and concentrated at crypt-villus junctions. Immunoelectron microscopy revealed plasmalemmal OTR at enterocyte adherens junctions. We suggest that OT and OTR signaling might be important in ENS development and function and might play roles in visceral sensory perception and neural modulation of epithelial biology. PMID:19003903

  9. Knockdown of long non-coding RNA KCNQ1OT1 depressed chemoresistance to paclitaxel in lung adenocarcinoma.

    PubMed

    Ren, Kaiming; Xu, Ran; Huang, Jingshan; Zhao, Jungang; Shi, Wenjun

    2017-08-01

    Lung cancer, with the highest morbidity and second highest death rates, is one of the most common cancers in both males and females worldwide. Lung adenocarcinoma (LAD) is the main lung cancer class. KCNQ1 Opposite Strand/Antisense Transcript 1 (KCNQ1OT1) gene is an lncRNA which had been reported high-expression in colorectal cancer. In this study, the expression of KCNQ1OT1 was confirmed to be highly expressed in LAD tissues and cells contrast to control tissues and cells, and high KCNQ1OT1 expression correlated to malignant behaviors of LAD, including big tumor size, poor differentiation, positive lymphatic metastasis and high TNM stages. The transfection of si-KCNQ1OT1 could effectually knockdown the expression of KCNQ1OT1 in A549 and A549/PA cells. The KCNQ1OT1 knockdown depressed the proliferation and invasion of A549 cells, and advanced cellular apoptosis of A549 cells. The expression of KCNQ1OT1 in LAD patients insensitive to paclitaxel was much higher than that in LAD patients sensitive to paclitaxel; the KCNQ1OT1 expression in A549/PA cells was also much higher than that in control A549 cells. The half maximal inhibitory concentration (IC50) of paclitaxel in A549/PA cells was depressed by KCNQ1OT1 knockdown, chemoresistance of A549/PA cells was inhibited significantly. KCNQ1OT1 knockdown also depressed the expression of multidrug resistance 1 (MDR1) protein in A549/PA cells. In summary, lncRNA KCNQ1OT1 was highly expressed in LAD and functioned as a potential oncogene to inhibit malignancy and chemoresistance of LAD cells, which might be a novel potential therapeutic target for LAD.

  10. Expression and developmental regulation of oxytocin (OT) and oxytocin receptors (OTR) in the enteric nervous system (ENS) and intestinal epithelium.

    PubMed

    Welch, Martha G; Tamir, Hadassah; Gross, Kara J; Chen, Jason; Anwar, Muhammad; Gershon, Michael D

    2009-01-10

    Although oxytocin (OT) and oxytocin receptor (OTR) are known for roles in parturition and milk let-down, they are not hypothalamus-restricted. OT is important in nurturing and opposition to stress. Transcripts encoding OT and OTR have been reported in adult human gut, and OT affects intestinal motility. We tested the hypotheses that OT is endogenous to the enteric nervous system (ENS) and that OTR signaling may participate in enteric neurophysiology. Reverse transcriptase polymerase chain reaction confirmed OT and OTR transcripts in adult mouse and rat gut and in precursors of enteric neurons immunoselected from fetal rats. Enteric OT and OTR expression continued through adulthood but was developmentally regulated, peaking at postnatal day 7. Coincidence of the immunoreactivities of OTR and the neural marker Hu was 100% in the P3 and 71% in the adult myenteric plexus, when submucosal neurons were also OTR-immunoreactive. Co-localization with NeuN established that intrinsic primary afferent neurons are OTR-expressing. Because OTR transcripts and protein were detected in the nodose ganglia, OT signaling might also affect extrinsic primary afferent neurons. Although OT immunoreactivity was found only in approximately 1% of myenteric neurons, extensive OT-immunoreactive varicosities surrounded many others. Villus enterocytes were OTR-immunoreactive through postnatal day 17; however, by postnatal day 19, immunoreactivity waned to become restricted to crypts and concentrated at crypt-villus junctions. Immunoelectron microscopy revealed plasmalemmal OTR at enterocyte adherens junctions. We suggest that OT and OTR signaling might be important in ENS development and function and might play roles in visceral sensory perception and neural modulation of epithelial biology.

  11. 12 CFR 516.220 - If OTS requests additional information to complete my application, how will it process my...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... complete my application, how will it process my application? 516.220 Section 516.220 Banks and Banking... Standard Treatment § 516.220 If OTS requests additional information to complete my application, how will it... your response. OTS will notify you that it has extended the period before the end of the initial 15-day...

  12. 12 CFR 502.26 - How does OTS calculate the semi-annual assessment for savings and loan holding companies?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... follows: (1) OTS will assess a base assessment amount of $3,500 on responsible savings and loan holding...-site supervision of a noncomplex, low risk savings and loan holding company structure. OTS will... savings and loan holding companies: a component based on the risk or complexity of the savings and...

  13. Long non-coding RNA SOX2OT: expression signature, splicing patterns, and emerging roles in pluripotency and tumorigenesis

    PubMed Central

    Shahryari, Alireza; Jazi, Marie Saghaeian; Samaei, Nader M.; Mowla, Seyed J.

    2015-01-01

    SOX2 overlapping transcript (SOX2OT) is a long non-coding RNA which harbors one of the major regulators of pluripotency, SOX2 gene, in its intronic region. SOX2OT gene is mapped to human chromosome 3q26.3 (Chr3q26.3) locus and is extended in a high conserved region of over 700 kb. Little is known about the exact role of SOX2OT; however, recent studies have demonstrated a positive role for it in transcription regulation of SOX2 gene. Similar to SOX2, SOX2OT is highly expressed in embryonic stem cells and down-regulated upon the induction of differentiation. SOX2OT is dynamically regulated during the embryogenesis of vertebrates, and delimited to the brain in adult mice and human. Recently, the disregulation of SOX2OT expression and its concomitant expression with SOX2 have become highlighted in some somatic cancers including esophageal squamous cell carcinoma, lung squamous cell carcinoma, and breast cancer. Interestingly, SOX2OT is differentially spliced into multiple mRNA-like transcripts in stem and cancer cells. In this review, we are describing the structural and functional features of SOX2OT, with an emphasis on its expression signature, its splicing patterns and its critical function in the regulation of SOX2 expression during development and tumorigenesis. PMID:26136768

  14. 12 CFR 516.220 - If OTS requests additional information to complete my application, how will it process my...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false If OTS requests additional information to complete my application, how will it process my application? 516.220 Section 516.220 Banks and Banking... Standard Treatment § 516.220 If OTS requests additional information to complete my application, how will it...

  15. 12 CFR 516.220 - If OTS requests additional information to complete my application, how will it process my...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 6 2013-01-01 2012-01-01 true If OTS requests additional information to complete my application, how will it process my application? 516.220 Section 516.220 Banks and Banking... Standard Treatment § 516.220 If OTS requests additional information to complete my application, how will it...

  16. 12 CFR 516.220 - If OTS requests additional information to complete my application, how will it process my...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 6 2012-01-01 2012-01-01 false If OTS requests additional information to complete my application, how will it process my application? 516.220 Section 516.220 Banks and Banking... Standard Treatment § 516.220 If OTS requests additional information to complete my application, how will it...

  17. 12 CFR 516.220 - If OTS requests additional information to complete my application, how will it process my...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 6 2014-01-01 2012-01-01 true If OTS requests additional information to complete my application, how will it process my application? 516.220 Section 516.220 Banks and Banking... Standard Treatment § 516.220 If OTS requests additional information to complete my application, how will it...

  18. 12 CFR 502.26 - How does OTS calculate the semi-annual assessment for savings and loan holding companies?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... condition. OTS determines the amount of each component under §§ 502.27 through 502.29 of this part. (b) For... reflect OTS costs of supervising the holding company structure and: (i) There are multiple top-tier holding companies in the holding company structure; (ii) The top-tier holding company is organized...

  19. Learning client-centred practice short report: experience of OT students interacting with "expert patients".

    PubMed

    Cameron, Jasmin Joan; McColl, Mary Ann

    2015-07-01

    Client-centered care, a core value of occupational therapy (OT) and the gold standard of health care, presents challenges in practice. Learning client-centered practice (CCP) in health professional education has been linked to use of "expert patients". How this learning occurs was acknowledged as a gap in research. This article aims to describe OT students' experience interacting with "expert patients"; describe students' learning regarding CCP; identify conditions for learning CCP. MScOT students participated in a qualitative study with the research question: "How does the students' experience interacting with the 'expert patient' relate to learning regarding client-centred practice?" In-depth interviews were conducted with six OT students subsequent to their "expert patient" sessions. Transcripts were analyzed using CAQDAS. Students described admiration, discomfort, humility, and gratefulness; learning regarding collaboration; respect for autonomy; and recognition of client expertise. Three coexistent conditions fostered learning regarding CCP: the client is an expert; students experience power; and the environment includes guided reflection/discussion. This study adds to the literature particular conditions that facilitate learning client-centered practice. All stakeholders in health professional education can benefit.

  20. Use of thermal cycling to reduce adhesion of OTS coated coated MEMS cantilevers

    NASA Astrophysics Data System (ADS)

    Ali, Shaikh M.; Phinney, Leslie M.

    2003-01-01

    °Microelectromechanical systems (MEMS) have enormous potential to contribute in diverse fields such as automotive, health care, aerospace, consumer products, and biotechnology, but successful commercial applications of MEMS are still small in number. Reliability of MEMS is a major impediment to the commercialization of laboratory prototypes. Due to the multitude of MEMS applications and the numerous processing and packaging steps, MEMS are exposed to a variety of environmental conditions, making the prediction of operational reliability difficult. In this paper, we investigate the effects of operating temperature on the in-use adhesive failure of electrostatically actuated MEMS microcantilevers coated with octadecyltrichlorosilane (OTS) films. The cantilevers are subjected to repeated temperature cycles and electrostatically actuated at temperatures between 25°C and 300°C in ambient air. The experimental results indicate that temperature cycling of the OTS coated cantilevers in air reduces the sticking probability of the microcantilevers. The sticking probability of OTS coated cantilevers was highest during heating, which decreased during cooling, and was lowest during reheating. Modifications to the OTS release method to increase its yield are also discussed.

  1. 78 FR 76721 - Removal of Transferred OTS Regulations Regarding Recordkeeping and Confirmation Requirements for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-19

    ... securities transactions effected on behalf of customers by all FDIC-supervised institutions will be found at... securities transactions effected for customers by State savings associations.\\3\\ The former OTS rule was... requirements for securities transactions ] effected for customers by insured State nonmember banks and insured...

  2. Pre-discovery observations of MASTER OT J004514.13+420007.2

    NASA Astrophysics Data System (ADS)

    Maehara, Hiroyuki

    2016-01-01

    I report pre-discovery observations of the possible nova in M31 MASTER OT J004514.13+420007.2 (ATel # 8603). The observations were performed with the 1.05-m Schmidt telescope and KWFC (Sako et al. 2012, SPIE, 8446, 84466L) at Kiso Observatory.

  3. Optimal Diphthongs: An OT Analysis of the Acquisition of Spanish Diphthongs

    ERIC Educational Resources Information Center

    Krause, Alice

    2013-01-01

    This dissertation investigates the acquisition of Spanish diphthongs by adult native speakers of English. The following research questions will be addressed: 1) How do adult native speakers of English pronounce sequences of two vowels in their L2 Spanish at different levels of acquisition? 2) Can OT learnability models, specifically the GLA,…

  4. 12 CFR 516.15 - Must I meet with OTS before I file my application?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... with OTS before filing your application. You must submit a draft business plan before this meeting. (2... you to submit a draft business plan or other relevant information before this meeting. (b) Contacting... pre-filing meeting or a draft business plan, the Regional Office will determine whether it...

  5. 12 CFR 516.15 - Must I meet with OTS before I file my application?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... with OTS before filing your application. You must submit a draft business plan before this meeting. (2... you to submit a draft business plan or other relevant information before this meeting. (b) Contacting... pre-filing meeting or a draft business plan, the Regional Office will determine whether it...

  6. 12 CFR 563b.205 - May a court review OTS's final action on my conversion?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    .... Court of Appeals for the District of Columbia Circuit, to review the action under 12 U.S.C. 1464(i)(2)(B... 12 Banks and Banking 6 2013-01-01 2012-01-01 true May a court review OTS's final action on my conversion? 563b.205 Section 563b.205 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF...

  7. 12 CFR 563b.205 - May a court review OTS's final action on my conversion?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    .... Court of Appeals for the District of Columbia Circuit, to review the action under 12 U.S.C. 1464(i)(2)(B... 12 Banks and Banking 6 2014-01-01 2012-01-01 true May a court review OTS's final action on my conversion? 563b.205 Section 563b.205 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF...

  8. 12 CFR 563b.205 - May a court review OTS's final action on my conversion?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    .... Court of Appeals for the District of Columbia Circuit, to review the action under 12 U.S.C. 1464(i)(2)(B... 12 Banks and Banking 6 2012-01-01 2012-01-01 false May a court review OTS's final action on my conversion? 563b.205 Section 563b.205 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF...

  9. 12 CFR 563b.205 - May a court review OTS's final action on my conversion?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    .... Court of Appeals for the District of Columbia Circuit, to review the action under 12 U.S.C. 1464(i)(2)(B... 12 Banks and Banking 5 2011-01-01 2011-01-01 false May a court review OTS's final action on my conversion? 563b.205 Section 563b.205 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF...

  10. 12 CFR 563b.205 - May a court review OTS's final action on my conversion?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    .... Court of Appeals for the District of Columbia Circuit, to review the action under 12 U.S.C. 1464(i)(2)(B... 12 Banks and Banking 5 2010-01-01 2010-01-01 false May a court review OTS's final action on my conversion? 563b.205 Section 563b.205 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF...

  11. GROND upper limits for MASTER OT103630.69-003523.8

    NASA Astrophysics Data System (ADS)

    Greiner, Jochen; Rau, Arne; Olivares E, Felipe

    2012-01-01

    Following the report of the discovery of MASTER OT103630.69-003523.8 (Lipunov et al. 2012, ATel #3844) we initiated simultaneous g'r'i'zJHK GROND (Greiner et al. 2008, PASP, 120, 405) on January 5th, 2012, at 06:53 UT. We do not detect the source to the following limits (all in AB).

  12. Optimal Diphthongs: An OT Analysis of the Acquisition of Spanish Diphthongs

    ERIC Educational Resources Information Center

    Krause, Alice

    2013-01-01

    This dissertation investigates the acquisition of Spanish diphthongs by adult native speakers of English. The following research questions will be addressed: 1) How do adult native speakers of English pronounce sequences of two vowels in their L2 Spanish at different levels of acquisition? 2) Can OT learnability models, specifically the GLA,…

  13. Spectroscopic Classification of MASTER OT J081506.13+381123.3 as a Type Ia Supernova

    NASA Astrophysics Data System (ADS)

    Rui, Liming; Li, Wenxiong; Chen, Zhihao; Xiang, Danfeng; Wang, Xiaofeng; Zhang, Tianmeng; Zhang, Jichen; Zhang, Ziyan; Luo, Zhe; Cui, Can; Li, Yaxin; ), Xinhang Shen

    2017-01-01

    We obtained an optical spectrum (range 360-860 nm) of MASTER OT J081506.13+381123.3 (see ATEL #9971), discovered by MASTER robotic Net, on UT Jan.20.6 2017 with the 2.16-m telescope (+BFOSC) at Xinglong Station of National Astronomical Observatories of China (NAOC).

  14. 12 CFR 585.120 - What factors will OTS consider in reviewing my application?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 5 2011-01-01 2011-01-01 false What factors will OTS consider in reviewing my application? 585.120 Section 585.120 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE... question whether a person who was convicted of a crime or who agreed to enter into a pretrial diversion or...

  15. 12 CFR 516.10 - How does OTS compute time periods under this part?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... time periods under this part, OTS does not include the day of the act or event that commences the time period. When the last day of a time period is a Saturday, Sunday, or Federal holiday, the time period runs until the end of the next day that is not a Saturday, Sunday, or Federal holiday. ...

  16. 75 FR 76524 - Closed Meeting of the OTS Mutual Savings Association Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-08

    .... SUMMARY: The OTS Mutual Savings Associations Advisory Committee (MSAAC) will convene a meeting on Monday... meeting will be held on Monday, December 20, 2010, at Noon, Eastern Time. ADDRESSES: The meeting will be... Savings Association Advisory Committee will convene a closed meeting on Monday, December 20,...

  17. "Merging Yoga and Occupational Therapy (MY-OT): A feasibility and pilot study".

    PubMed

    Schmid, Arlene A; Puymbroeck, Marieke Van; Portz, Jennifer D; Atler, Karen E; Fruhauf, Christine A

    2016-10-01

    To examine the feasibility and benefits of the Merging Yoga and Occupational Therapy (MY-OT) intervention. This is the primary analysis of a non-controlled pretest-posttest pilot study to understand the feasibility and impact of MY-OT on balance, balance self-efficacy, and fall risk factor management in people with chronic stroke. University research laboratory. People with chronic stroke were included in the study if they: had sustained a fall or had fear of falling, were able to stand, and hand impaired balance and were at risk for falls (≤46 on the Berg Balance Scale (BBS)). Individuals completed an 8 week intervention that included 16 sessions of both yoga and group occupational therapy (OT). Yoga included physical postures, breathing exercises, and meditation. OT focused on post-stroke fall risk factor management. The BBS was used to assess balance, the Activities-specific Balance Confidence Scale (ABC) was used to measure balance self-efficacy. Five fall risk factor management scales were used. Overall, the intervention was considered feasible, as individuals were able to safely complete the intervention with little attrition and high attendance. Balance improved by 30% (p=0.002). Balance self-efficacy improved by 15% (p=0.034). Each of the five fall risk factor management scales improved, but only two significantly improved (Fall Prevention and Management Questionnaire, 29%, p=0.004 and Fall Prevention Strategy Survey, 42%, p=0.032). The results demonstrate that MY-OT is a potential intervention to improve multiple fall related outcomes for people with stroke. Therapists may consider these interventions for people with stroke, but additional research is warranted. Copyright © 2016 Elsevier Ltd. All rights reserved.

  18. 12 CFR 502.27 - How does OTS determine the risk/complexity component for a savings and loan holding company?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... affiliates. The OTS holding company risk/complexity classification system is more fully described in the OTS... highest risk holding companies under the holding company risk/complexity classification system; (ii) is... classifications and total consolidated holding company assets. OTS will establish these schedules in a Thrift...

  19. 12 CFR 502.27 - How does OTS determine the risk/complexity component for a savings and loan holding company?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false How does OTS determine the risk/complexity...-Calculation of Assessments § 502.27 How does OTS determine the risk/complexity component for a savings and loan holding company? (a) OTS computes the risk/complexity component for responsible savings and...

  20. Effects of diethylenetriamine and Aerosol OT on the stability of oil-in-water emulsion stabilized by interfacial polyurea film.

    PubMed

    Mikami, T

    1994-01-01

    The stability of oil-in-water emulsions containing a triisocyanate soluble in the oil phase and an amine in the water phase was investigated. The oil component was di-n-butyl phthalate (DBP) containing Aerosol OT as an emulsifier. The time required for the average size parameter to reach a constant value was studied. It was found that the polyurea film produced by an interfacial polymerization reaction between the amine and the triisocyanate contributed to forming a stable emulsion at a lower Aerosol OT concentration, but at a higher Aerosol OT concentration the amine did not show any effect on the emulsion stability.

  1. MASTER OT J010603.18-744715.8 = Nova in SMC (Tucana)

    NASA Astrophysics Data System (ADS)

    Waagen, Elizabeth O.

    2016-10-01

    AAVSO Alert Notice 557 reports the discovery of a nova in the Small Magellanic Cloud (MASTER OT J010603.18-744715.8) by the MASTER-OAFA auto-detection system (Shumkov et al., ATel #9621) at 10.9 unfiltered CCD magnitude 10.9 on 2016 October 14.19341 UT. Spectroscopy indicating that MASTER OT J010603.18-744715.8 is a classical nova was obtained 2016 Oct 14.70 UT by Williams and Darnley (ATel #9628). Kuin et al. (ATel #9635) report that 500 seconds of observations by Swift centered on 2016 Oct. 15.3056 UT did not detect X-rays. Finder charts with sequence may be created using the AAVSO Variable Star Plotter (https://www.aavso.org/vsp). Observations should be submitted to the AAVSO International Database. See full Alert Notice for more details.

  2. History of Air Force Operational Test and Evaluation (OT and E) Mission, Organization, and Policy

    DTIC Science & Technology

    1992-12-01

    objectives. For tests involving large volumes of data, team analysts and Headquarters AFOTEC-augmented by support contractors-use automated data reduction...with OT&E. 41 77. For discussions of these issues, see Chapter I in annual histories of AFOTEC starting in 1984. 78. United States Code Annotated Feb 90...83 missile, 1983-88 A-10 Operational Flight Trainer AQM-81A Firebolt, 1984-85 (OFT), 1980-82 Automated Data Processing System, Advanced Aerial

  3. MASTER: bright OT discovered during Fermi trigger 512353690/GRB170328A inspection

    NASA Astrophysics Data System (ADS)

    Gorbovskoy, E.; Lipunov, V.; Buckley, D.; Rebolo, R.; Serra-Ricart, M.; Gress, O.; Tiurina, N.; Balanutsa, P.; Kornilov, V.; Vladimirov, V.

    2017-03-01

    MASTER-SAAO auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 18h 45m 46.55s -35d 28m 47.6s on 2017-03-28.06645 UT during Fermi trigger 512353690(GRB170328A) inspection https://gcn.gsfc.nasa.gov/other/512353690.fermi (trigger time is 17/03/28 00:28:05.53UT).

  4. MASTER-SAAO: bright PSN in PGC600519 and 2 OTs

    NASA Astrophysics Data System (ADS)

    Pogrosheva, T.; Balanutsa, P.; Lipunov, V.; Buckley, D.; Gorbovskoy, E.; Tiurina, N.; Gress, O.; Shumkov, V.; Kuznetsov, A.; Kornilov, V.; Chazov, V.; Vladimirov, V.; Vlasenko, D.; Potter, S.

    2016-10-01

    MASTER-SAAO auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 10h 54m 40.86s , -39d 13m 19s.0 on 2016-10-08 02:56:46.019UT with . This PSN is in 2.9"E,7"N from the center of PGC600519 and is seen on 8 images.

  5. Computer software design description for the Treated Effluent Disposal Facility (TEDF), Project L-045H, Operator Training Station (OTS)

    SciTech Connect

    Carter, R.L. Jr.

    1994-11-07

    The Treated Effluent Disposal Facility (TEDF) Operator Training Station (OTS) is a computer-based training tool designed to aid plant operations and engineering staff in familiarizing themselves with the TEDF Central Control System (CCS).

  6. 12 CFR 502.29 - How does OTS determine the condition component for a savings and loan holding company?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... holding company structure) is a composite rating of 4 or 5, OTS will assess a charge under the condition... amount, the risk/complexity component, and any organizational form component. (b) For the purposes...

  7. 12 CFR 502.29 - How does OTS determine the condition component for a savings and loan holding company?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... holding company structure) is a composite rating of 4 or 5, OTS will assess a charge under the condition... amount, the risk/complexity component, and any organizational form component. (b) For the purposes...

  8. 12 CFR 502.29 - How does OTS determine the condition component for a savings and loan holding company?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... holding company structure) is a composite rating of 4 or 5, OTS will assess a charge under the condition... amount, the risk/complexity component, and any organizational form component. (b) For the purposes...

  9. Gene expression profiles of prohibitin in testes of Octopus tankahkeei (ot-phb) revealing its possible role during spermiogenesis.

    PubMed

    Mao, Hai-Tao; Wang, Da-Hui; Lan, Zhou; Zhou, Hong; Yang, Wan-Xi

    2012-05-01

    Prohibitin is essential for intracellular homeostasis and stabilization of mitochondrial respiratory chain complexes. To explore its functions during spermiogenesis of Octopus tankahkeei (O. tankahkeei), we have cloned and sequenced the cDNA of this mammalian PHB homologue (termed ot-PHB) from the testes of O. tankahkeei. The 1165 bp ot-phb cDNA contains a 100 bp 5' UTR, a 882 bp open reading frame and a 183 bp 3' UTR. The putative ot-PHB protein owns a transmembrane domain from 6 to 31 amino acid (aa) and a putative PHB domain from 26 to 178 aa. Protein alignment demonstrated that ot-PHB had 73.3, 73.6, 74.0, 75.1, and 45.4% identity with its homologues in Homo sapiens, Mus muculus, Danio rerio, Xenopus tropicalis and Trypanosoma brucei, respectively. Tissue distribution profile analysis revealed its presence in all the tissues examined. In situ hybridization in spermiogenic cells demonstrated that ot-phb was expressed moderately at the beginning of the spermiogenesis. The abundance of transcripts increased in intermediate spermatids and in drastically remodeling final spermatids. In mature spermatozoa, the residuary transcripts concentrated around the chondriosomal mantle where mitochondria assemble around. In summary, the expression of ot-phb during spermiogenesis implicates a potential function of this protein during mitochondrial ubiquitination. It is the first time to implicate the role of prohibitin in cephalopod spermiogenesis.

  10. Long Noncoding RNA-Sox2OT Knockdown Alleviates Diabetes Mellitus-Induced Retinal Ganglion Cell (RGC) injury.

    PubMed

    Li, Chao-Peng; Wang, Shu-Hong; Wang, Wen-Qi; Song, Shu-Guang; Liu, Xiu-Ming

    2017-03-01

    Retinal ganglion cell (RGC) injury is one of the important pathological features of diabetes-induced retinal neurodegeneration. Increasing attention has been paid to find strategies for protecting against RGC injury. Long noncoding RNAs (lncRNAs) have emerged as the key regulators of many cell functions. Here, we show that Sox2OT expression is significantly down-regulated in the retinas of STZ-induced diabetic mice and in the RGCs upon high glucose or oxidative stress. SOX2OT knockdown protects RGCs against high glucose-induced injury in vitro. Moreover, Sox2OT knockdown plays a neuroprotective role in diabetes-related retinal neurodegeneration in vivo. Sox2OT knockdown could regulate oxidative stress response in RGCs and diabetic mouse retinas. Sox2OT knockdown plays an anti-oxidative role via regulating NRF2/HO-1 signaling activity. Taken together, Sox2OT knockdown may be a therapeutic strategy for the prevention and treatment of diabetes-induced retinal neurodegeneration.

  11. Structural insight into dephosphorylation by trehalose 6-phosphate phosphatase (OtsB2) from Mycobacterium tuberculosis.

    PubMed

    Shan, Shan; Min, Haowei; Liu, Ting; Jiang, Dunquan; Rao, Zihe

    2016-12-01

    Trehalose serves as a key structural component in the cell wall of Mycobacterium tuberculosis. M. tuberculosis trehalose-6-phosphate phosphatase (MtbTPP), an essential enzyme in the trehalose biosynthesis OtsAB pathway, catalyzes the dephosphorylation of trehalose-6-phosphate (trehalose-6-P) to generate trehalose, and plays a critical role in M. tuberculosis survival-associated cell wall formation and permeability. Therefore, MtbTPP (OtsB2) is considered a promising potential target for discovery of antimicrobial drugs. However, the absence of structural information of MtbTPP restrains our understanding of its underlying catalytic mechanism. Here, we report the high-resolution crystal structures of apo active MtbTPP and its trehalose-6-P bound complex. The apo structure presents a canonical haloacid dehalogenase superfamily structural fold plus an extra N-terminal domain. The catalytic center is located in a positively charged cleft between the hydrolase domain and the cap domain, demonstrating a highly conserved substrate binding pocket. The role of residues interacting with the substrate in catalysis were probed by site-directed mutagenesis. Asp147, Asp149, Asp330, and Asp331 were found to be pivotal for the enzymatic activity of MtbTPP. The MtbTPP structures reported here provide insight into a key step in the biosynthesis of trehalose, which would facilitate future development of anti-TB therapeutics.-Shan, S., Min, H., Liu, T., Jiang, D., Rao, Z. Structural insight into dephosphorylation by trehalose 6-phosphate phosphatase (OtsB2) from Mycobacterium tuberculosis.

  12. MASTER OT J095503.19-355149.4 - a probable Dwarf Nova

    NASA Astrophysics Data System (ADS)

    Buckley, D. A. H.; Kniazev, A.; Potter, S. B.; Lipunov, V.; Tiurina, N.; Gorbovskoy, E.

    2016-02-01

    Followup optical imaging and spectroscopic observations with SALT of the optical transient MASTER OT J095503.19-355149.4, tentatively identified (ATel #8741) as the optical counterpart of the Fermi GBM trigger 478121068 (GCN #19092), were conducted on 2016-02-26.78 UT. From un-calibrated g', r' and i' exposures (30 sec each) with the SALTICAM CCD camera, the transient appeared to be approximately 1 mag brighter (V ~ 17) than the MASTER-SAAO observations of the previous night (reported in ATel #8741) and was also seen to be a relatively red object compared to other stars in the field.

  13. Further Brightening of MASTER OT J132501.00+431846.1

    NASA Astrophysics Data System (ADS)

    Denisenko, D.

    2017-06-01

    Large amplitude optical transient MASTER OT J132501.00+431846.1 was discovered by MASTER robotic telescopes network (P. Balanutsa et al., ATel #10470). The following unfiltered magnitude in MASTER system (calibrated against USNO-B1.0 0.2B+0.8R) was reported: 2017-06-05.955 UT 15.4m MASTER-IAC Follow up observations were performed remotely using iTelescope.Net instruments in Nerpio, Spain (T18), Auberry, CA, USA (T24) and Mayhill, NM, USA (T11) under the full Moon conditions.

  14. Spectroscopic classification of PSN J13144705+5405055 (= MASTER OT J131447.05+540505.5)

    NASA Astrophysics Data System (ADS)

    Vanni, S.; Pastorello, A.; Benetti, S.; Cappellaro, E.; Ochner, P.; Tomasella, L.; Turatto, M.

    2012-11-01

    We report that optical spectroscopy (range 340-820 nm; resolution 1.3 nm) obtained on Nov. 8.18 UT with the Asiago 1.82-m Copernico Telescope (+ AFOSC), shows that PSN J13144705+5405055 (= MASTER OT J131447.05+540505.5) is a type-Ia SN at a redshift z~0.033 (Sloan Digital Sky Survey Data Release 3). The best match was found with type-Ia SN 2002bo (Benetti et al. 2004, MNRAS, 348, 261) about 3-4 weeks after the B band maximum light.

  15. Complete Genome Sequence of the Larvicidal Bacterium Lysinibacillus sphaericus Strain OT4b.25

    PubMed Central

    Rey, Andrés; Silva-Quintero, Laura

    2016-01-01

    Lysinibacillus sphaericus OT4b.25 is a native Colombian strain isolated from coleopteran larvae in an oak forest near Bogotá D.C.; this strain has shown high levels of pathogenic activity against Culex quinquefasciatus larvae in laboratory assays compared to that of other members of the same species. Using Pacific Biosciences sequencing technology, we propose a chromosomal contig of 4,665,775 bp that, according to comparative analysis, is highly similar to that of reference strain L. sphaericus C3-41. PMID:27151786

  16. SpOT the Correct Tissue Every Time in Multi-tissue Blocks

    PubMed Central

    Coffey, Anna; Johnson, Michael D.; Berry, Deborah L.

    2015-01-01

    Multi-tissue paraffin blocks provide high throughput analysis with increased efficiency, experimental uniformity, and reduced time and cost. Tissue microarrays make up the majority of multi-tissue paraffin blocks, but increasingly, researchers are using non-arrayed blocks containing larger tissues from multiple individuals which can provide many of the advantages of tissue microarrays without substantial investment in planning and equipment. A critical component of any multi-tissue analysis is the orientation method used to identify each individual tissue. Although methods exist to maintain proper orientation and identification of tissues in multi-tissue blocks, most are not well-suited to non-arrayed blocks, may consume valuable space within an array and/or are difficult to produce in the standard histology laboratory. The Specimen Orientation Tag (SpOT) is a simple, low cost orientation tool that is clearly visible in paraffin blocks and all tissue sections for reliable specimen identification in arrayed and non-arrayed layouts. The SpOT provides advantages over existing orientation methods for non-arrayed blocks as it does not require any direct modification to the tissue and allows for flexibility in the arrangement of tissue pieces. PMID:26067587

  17. Solar-energy-system performance evaluation: Honeywell OTS 44, Ocmulgee, Georgia

    NASA Astrophysics Data System (ADS)

    Mathur, A. K.; Pederson, S.

    1982-08-01

    The operation and technical performance of the solar operational test site (OTS 44) are described, based on data collected between April, 1981 and August, 1981. The following topics are discussed: system description, performance assessment, operating energy, energy savings, system maintenance, and conclusions. The solar energy system at OTS 44 is a hydronic heating and cooling system consisting of 5040 square feet of liquid cooled flat plate collectors; a 4000 gallon thermal storage tank; one 25 ton capacity organic Rankine cycle engine assisted water chillers; a forced draft cooling tower; and associated piping, pumps, valves, controls and heat rejection equipment. The solar system has eight basic modes of operation and several combination modes for providing space conditioning and hot water to the building. Data monitored during the 4 months of the operational test period found that the solar system collected 285 MMBtu of thermal energy of the total incident solar energy of 1040 MMBtu and provided 210 MMBtu for cooling and 10 MMBtu for heating and hot water. The net electrical energy saving due to the solar system was approximately 2600 kWh(e), and fossil energy saving was about 20 million Btu (MMBtu).

  18. Solar-energy-system performance evaluation: Honeywell OTS 44, Ocmulgee, Georgia

    NASA Technical Reports Server (NTRS)

    Mathur, A. K.; Pederson, S.

    1982-01-01

    The operation and technical performance of the solar operational test site (OTS 44) are described, based on data collected between April, 1981 and August, 1981. The following topics are discussed: system description, performance assessment, operating energy, energy savings, system maintenance, and conclusions. The solar energy system at OTS 44 is a hydronic heating and cooling system consisting of 5040 square feet of liquid cooled flat plate collectors; a 4000 gallon thermal storage tank; one 25 ton capacity organic Rankine cycle engine assisted water chillers; a forced draft cooling tower; and associated piping, pumps, valves, controls and heat rejection equipment. The solar system has eight basic modes of operation and several combination modes for providing space conditioning and hot water to the building. Data monitored during the 4 months of the operational test period found that the solar system collected 285 MMBtu of thermal energy of the total incident solar energy of 1040 MMBtu and provided 210 MMBtu for cooling and 10 MMBtu for heating and hot water. The net electrical energy saving due to the solar system was approximately 2600 kWh(e), and fossil energy saving was about 20 million Btu (MMBtu).

  19. DeSSpOt: an instrument for stellar spin orientation determination

    NASA Astrophysics Data System (ADS)

    Lesage, Anna-Lea; Schneide, Magnus; Wiedemann, Günter

    2012-09-01

    We designed and constructed a special instrument to enable the determination of the stellar's spin orientation. The Differential image rotator for Stellar Spin Orientation, DeSSpOt, allows the simultaneous observations of two anti-parallel orientations of the star on the spectrum. On a high resolution échelle spectrum, the stellar rotation causes a slight line tilt visible in the spatial direction which is comparable to a rotation curve. We developed a new method, which exploits the variations in these tilts, to estimate the absolute position angle of the rotation axis. The line tilt is retrieved by a spectroastrometric extraction of the spectrum. In order to validate the method, we observed spectroscopic binaries with known orbital parameters. The determination of the orbital position angle is equivalent to the determination of the stellar position angle, but is easier to to detect. DeSSpOt was successfully implemented on the high resolution Coudé spectrograph of the Thüringer Landessternwarte Tautenburg. The observations of Capella led to the determination of the orbital position angle. Our value of 37.2° is in agreement with the values previously found in the literature. As such we verified that both method and instrument are valid.

  20. Solar energy system performance evaluation - final report for Honeywell OTS 45, Salt River Project, Phoenix, Arizona

    SciTech Connect

    Mathur, A K

    1983-09-01

    This report describes the operation and technical performance of the Solar Operational Test Site (OTS 45) at Salt River Project in Phoenix, Arizona, based on the analysis of data collected between April 1981 and March 31, 1982. The following topics are discussed: system description, performance assessment, operating energy, energy savings, system maintenance, and conclusions. The solar energy system at OTS 45 is a hydronic heating and cooling system consisting of 8208 square feet of liquid-cooled flat-plate collectors; a 2500-gallon thermal storage tank; two 25-ton capacity organic Rankine-cycle-engine-assisted water chillers; a forced-draft cooling tower; and associated piping, pumps, valves, controls and heat rejection equipment. The solar system has eight basic modes of operation and several combination modes. The system operation is controlled automatically by a Honeywell-designed microprocessor-based control system, which also provides diagnostics. Based on the instrumented test data monitored and collected during the 8 months of the Operational Test Period, the solar system collected 1143 MMBtu of thermal energy of the total incident solar energy of 3440 MMBtu and provided 241 MMBtu for cooling and 64 MMBtu for heating. The projected net annual electrical energy savings due to the solar system was approximately 40,000 kWh(e).

  1. Solar energy system performance evaluation: Honeywell OTS 41, Shenandoah (Newman), Georgia

    NASA Astrophysics Data System (ADS)

    Mathur, A. K.; Pederson, S.

    1982-08-01

    The operation and technical performance of the Solar Operational Test Site (OTS 41) located at Shenandoah, Georgia, are described, based on the analysis of the data collected between January and August 1981. The following topics are discussed: system description, performance assessment, operating energy, energy savings, system maintenance, and conclusions. The solar energy system at OTS 41 is a hydronic heating and cooling system consisting of 702 square feet of liquid-cooled flat-plate collectors; a 1000-gallon thermal storage tank; a 3-ton capacity organic Rankine-cycle-engine-assisted air conditioner; a water-to-are heat exchanger for solar space heating; a finned-tube coil immersed in the storage tank to preheat water for a gas-fired hot water heater; and associated piping, pumps, valves, and controls. The solar system has six basic modes of operation and several combination modes. The system operation is controlled automatically by a Honeywell-designed microprocessor-based control system, which also provides diagnostics.

  2. Kcnq1ot1/Lit1 Noncoding RNA Mediates Transcriptional Silencing by Targeting to the Perinucleolar Region ▿ †

    PubMed Central

    Mohammad, Faizaan; Pandey, Radha Raman; Nagano, Takashi; Chakalova, Lyubomira; Mondal, Tanmoy; Fraser, Peter; Kanduri, Chandrasekhar

    2008-01-01

    The Kcnq1ot1 antisense noncoding RNA has been implicated in long-range bidirectional silencing, but the underlying mechanisms remain enigmatic. Here we characterize a domain at the 5′ end of the Kcnq1ot1 RNA that carries out transcriptional silencing of linked genes using an episomal vector system. The bidirectional silencing property of Kcnq1ot1 maps to a highly conserved repeat motif within the silencing domain, which directs transcriptional silencing by interaction with chromatin, resulting in histone H3 lysine 9 trimethylation. Intriguingly, the silencing domain is also required to target the episomal vector to the perinucleolar compartment during mid-S phase. Collectively, our data unfold a novel mechanism by which an antisense RNA mediates transcriptional gene silencing of chromosomal domains by targeting them to distinct nuclear compartments known to be rich in heterochromatic machinery. PMID:18299392

  3. Genome sequence and description of the heavy metal tolerant bacterium Lysinibacillus sphaericus strain OT4b.31

    PubMed Central

    Peña-Montenegro, Tito David; Dussán, Jenny

    2013-01-01

    Lysinibacillus sphaericus strain OT4b.31 is a native Colombian strain having no larvicidal activity against Culex quinquefasciatus and is widely applied in the bioremediation of heavy-metal polluted environments. Strain OT4b.31 was placed between DNA homology groups III and IV. By gap-filling and alignment steps, we propose a 4,096,672 bp chromosomal scaffold. The whole genome (consisting of 4,856,302 bp long, 94 contigs and 4,846 predicted protein-coding sequences) revealed differences in comparison to the L. sphaericus C3-41 genome, such as syntenial relationships, prophages and putative mosquitocidal toxins. Sphaericolysin B354, the coleopteran toxin Sip1A and heavy metal resistance clusters from nik, ars, czc, cop, chr, czr and cad operons were identified. Lysinibacillus sphaericus OT4b.31 has applications not only in bioremediation efforts, but also in the biological control of agricultural pests. PMID:24501644

  4. Trehalose-6-Phosphate-Mediated Toxicity Determines Essentiality of OtsB2 in Mycobacterium tuberculosis In Vitro and in Mice

    PubMed Central

    Koliwer-Brandl, Hendrik; Hartman, Travis; Jacobs, William R.; Ioerger, Thomas R.; Ehrt, Sabine

    2016-01-01

    Trehalose biosynthesis is considered an attractive target for the development of antimicrobials against fungal, helminthic and bacterial pathogens including Mycobacterium tuberculosis. The most common biosynthetic route involves trehalose-6-phosphate (T6P) synthase OtsA and T6P phosphatase OtsB that generate trehalose from ADP/UDP-glucose and glucose-6-phosphate. In order to assess the drug target potential of T6P phosphatase, we generated a conditional mutant of M. tuberculosis allowing the regulated gene silencing of the T6P phosphatase gene otsB2. We found that otsB2 is essential for growth of M. tuberculosis in vitro as well as for the acute infection phase in mice following aerosol infection. By contrast, otsB2 is not essential for the chronic infection phase in mice, highlighting the substantial remodelling of trehalose metabolism during infection by M. tuberculosis. Blocking OtsB2 resulted in the accumulation of its substrate T6P, which appears to be toxic, leading to the self-poisoning of cells. Accordingly, blocking T6P production in a ΔotsA mutant abrogated otsB2 essentiality. T6P accumulation elicited a global upregulation of more than 800 genes, which might result from an increase in RNA stability implied by the enhanced neutralization of toxins exhibiting ribonuclease activity. Surprisingly, overlap with the stress response caused by the accumulation of another toxic sugar phosphate molecule, maltose-1-phosphate, was minimal. A genome-wide screen for synthetic lethal interactions with otsA identified numerous genes, revealing additional potential drug targets synergistic with OtsB2 suitable for combination therapies that would minimize the emergence of resistance to OtsB2 inhibitors. PMID:27936238

  5. Entraining IDyOT: Timing in the Information Dynamics of Thinking

    PubMed Central

    Forth, Jamie; Agres, Kat; Purver, Matthew; Wiggins, Geraint A.

    2016-01-01

    We present a novel hypothetical account of entrainment in music and language, in context of the Information Dynamics of Thinking model, IDyOT. The extended model affords an alternative view of entrainment, and its companion term, pulse, from earlier accounts. The model is based on hierarchical, statistical prediction, modeling expectations of both what an event will be and when it will happen. As such, it constitutes a kind of predictive coding, with a particular novel hypothetical implementation. Here, we focus on the model's mechanism for predicting when a perceptual event will happen, given an existing sequence of past events, which may be musical or linguistic. We propose a range of tests to validate or falsify the model, at various different levels of abstraction, and argue that computational modeling in general, and this model in particular, can offer a means of providing limited but useful evidence for evolutionary hypotheses. PMID:27803682

  6. Entraining IDyOT: Timing in the Information Dynamics of Thinking.

    PubMed

    Forth, Jamie; Agres, Kat; Purver, Matthew; Wiggins, Geraint A

    2016-01-01

    We present a novel hypothetical account of entrainment in music and language, in context of the Information Dynamics of Thinking model, IDyOT. The extended model affords an alternative view of entrainment, and its companion term, pulse, from earlier accounts. The model is based on hierarchical, statistical prediction, modeling expectations of both what an event will be and when it will happen. As such, it constitutes a kind of predictive coding, with a particular novel hypothetical implementation. Here, we focus on the model's mechanism for predicting when a perceptual event will happen, given an existing sequence of past events, which may be musical or linguistic. We propose a range of tests to validate or falsify the model, at various different levels of abstraction, and argue that computational modeling in general, and this model in particular, can offer a means of providing limited but useful evidence for evolutionary hypotheses.

  7. How Surface Heterogeneity Affects Protein Adsorption: Annealing of OTS Patterns and Albumin Adsorption Kinetics*

    PubMed Central

    Hodgkinson, Gerald N.; Hlady, Vladimir

    2009-01-01

    Fluorescence microscopy and intensity histogram analysis techniques were used to monitor spatially-resolved albumin adsorption kinetics to model heterogeneous surfaces on sub-μm scales. Several distinct protein subpopulations were resolved, each represented by a normal distribution of adsorption densities on the adsorbent surface. Histogram analyses provided dynamic information of mean adsorption density, spread in adsorption density, and surface area coverage for each distinct protein subpopulation. A simple adsorption model is proposed in which individual protein binding events are predicted by the summation of multiple protein's surface sub-site interactions with different binding energy sub-sites on adsorbent surfaces. This model is predictive of the albumin adsorption on the patterns produced by one step μ-contact printing (μCP) of octadecyltrichlorosilane (OTS) on glass but fails to describe adsorption once the same patterns are altered by a thermal annealing step. PMID:19746205

  8. The Persistent Eruption of UGC 2773-OT: finally, a decade-long extragalactic Eta Carinae analogue

    NASA Astrophysics Data System (ADS)

    Smith, Nathan; Andrews, Jennifer E.; Mauerhan, Jon C.; Zheng, WeiKang; Filippenko, Alexei V.; Graham, Melissa L.; Milne, Peter

    2016-02-01

    While supernova (SN) impostors resemble the Great Eruption of η Carinae in the sense that their spectra show narrow H lines and they have typical peak absolute magnitudes of -13 to -14 mag, most extragalactic events observed so far are quite different from η Car in duration. Their bright phases typically last for ˜100 d or less, rather than persisting for several years. The transient object UGC 2773-OT (discovered in 2009) had a similar peak absolute magnitude to other SN impostors, but with a gradual 5-yr pre-discovery rise. In the ˜6 yr since discovery, it has faded very slowly (0.26 mag yr-1). Overall, we suggest that its decade-long eruption is so far the best-known analogue of η Car's 19th century eruption. We discuss extensive spectroscopy of the ongoing eruption. The spectra show interesting changes in velocity and line shape that we discuss in detail, including an asymmetric Hα emission line that we show is consistent with the ejection of a bipolar nebula that could be very much like the Homunculus of η Car. Moreover, changes in the line width, line profile, blue excess emission resembling that of Type IIn SNe, and the intensity of Hα suggest the presence of strong circumstellar interaction in the eruption at late times. This supports the hypothesis that the extended plateau of η Car's eruption may have been powered by shock interaction as well. One interesting difference compared to η Car, however, is that UGC 2773-OT so far does not exhibit the repeated brief spikes in luminosity that have been associated with binary periastron events.

  9. Solar energy system performance evaluation: final report for Honeywell OTS 41, Shenandoah (Newnan), Georgia

    SciTech Connect

    Mathur, A K; Pederson, S

    1982-08-01

    The operation and technical performance of the Solar Operational Test Site (OTS 41) located at Shenandoah, Georgia, are described, based on the analysis of data collected between January and August 1981. The following topics are discussed: system description, performance assessment, operating energy, energy savings, system maintenance, and conclusions. The solar energy system at OTS 41 is a hydronic heating and cooling system consisting of 702 square feet of liquid-cooled flat-plate collectors; a 1000-gallon thermal storage tank; a 3-ton capacity organic Rankine-cycle-engine-assisted air conditioner; a water-to-air heat exchanger for solar space heating; a finned-tube coil immersed in the storage tank to preheat water for a gas-fired hot water heater; and associated piping, pumps, valves, and controls. The solar system has six basic modes of operation and several combination modes. The system operation is controlled automatically by a Honeywell-designed microprocessor-based control system, which also provides diagnostics. Based on the instrumented test data monitored and collected during the 7 months of the Operational Test Period, the solar system collected 53 MMBtu of thermal energy of the total incident solar energy of 219 MMBtu and provided 11.4 MMBtu for cooling, 8.6 MMBtu for heating, and 8.1 MMBtu for domestic hot water. The projected net annual energy savings due to the solar system were approximately 50 MMBtu of fossil energy (49,300 cubic feet of natural gas) and a loss of 280 kWh(e) of electrical energy.

  10. OT2_nflagey_2: Capturing missing evolved stars in the Galactic plane

    NASA Astrophysics Data System (ADS)

    Flagey, N.

    2011-09-01

    We discovered more than 400 compact shells in the MIPSGAL 24 microns survey of the Galactic plane. About 15% of all these objects were already known as planetary nebulae, supernova remnants, Wolf-Rayet stars, and luminous blue variables. The unknown bubbles are expected to be envelopes of evolved stars that could account for the ``missing massive stars in the Galaxy. Indeed, recent spectroscopic follow-ups in the near-IR and mid-IR have revealed several dust-free planetary nebulae with very hot central white dwarf and significantly increased the number of WR and LBV candidates. Our OT1 Priority 1 proposal just provided us with a first observation in the PACS-SED B2A mode of one object, revealing only a strong [N II] 122 microns line. Without further spectral information, identification and modeling of the target are impossible. However, analysis of the PACS and SPIRE data from the HiGal survey has recently enabled us to measure much higher detection rates of the shells in the far-IR than with MIPS 70 microns. We are thus very confident that dust features and/or gas lines can be detected with the PACS and SPIRE spectrometers. Therefore, we request complementary PACS-SED B2B and SPIRE-FTS observations on our OT1 sample. The complete far-IR/submm spectrum of each target will allow its unequivocal identification thanks to comparison with spectra of known evolved stars from the MESS key program. We will also model with much detail the different phases of the envelopes, thanks to our expertise in circumstellar envelopes, dust models and photoionization codes.

  11. 12 CFR 502.27 - How does OTS determine the risk/complexity component for a savings and loan holding company?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... other affiliates that are regulated financial entities, reputational risks raised by affiliation with... 12 Banks and Banking 5 2011-01-01 2011-01-01 false How does OTS determine the risk/complexity...-Calculation of Assessments § 502.27 How does OTS determine the risk/complexity component for a savings and...

  12. Facile synthesis of trifluoroethyl compounds by the Suzuki cross-coupling reactions of CF3CH2OTs with arylboronic acids.

    PubMed

    Leng, Faqiang; Wang, Yaping; Li, Hui; Li, Jingya; Zou, Dapeng; Wu, Yangjie; Wu, Yusheng

    2013-11-25

    This research provides a novel approach for introducing a CF3CH2 group onto aromatic rings using Pd(OAc)2/palladacycle as a catalyst for the Suzuki cross-coupling reaction of CF3CH2OTs (OTs = 4-methylbenzene sulfonate) with arylboronic acids.

  13. 12 CFR 516.290 - What will happen if OTS does not approve or disapprove my application within two calendar years...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... disapprove my application within two calendar years after the filing date? 516.290 Section 516.290 Banks and... within two calendar years after the filing date? (a) Withdrawal. If OTS has not approved or denied your pending application within two calendar years after the filing date under § 516.45, OTS will notify...

  14. 12 CFR 516.290 - What will happen if OTS does not approve or disapprove my application within two calendar years...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... disapprove my application within two calendar years after the filing date? 516.290 Section 516.290 Banks and... within two calendar years after the filing date? (a) Withdrawal. If OTS has not approved or denied your pending application within two calendar years after the filing date under § 516.45, OTS will notify...

  15. 12 CFR 516.290 - What will happen if OTS does not approve or disapprove my application within two calendar years...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... disapprove my application within two calendar years after the filing date? 516.290 Section 516.290 Banks and... within two calendar years after the filing date? (a) Withdrawal. If OTS has not approved or denied your pending application within two calendar years after the filing date under § 516.45, OTS will notify...

  16. 12 CFR 516.290 - What will happen if OTS does not approve or disapprove my application within two calendar years...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... disapprove my application within two calendar years after the filing date? 516.290 Section 516.290 Banks and... within two calendar years after the filing date? (a) Withdrawal. If OTS has not approved or denied your pending application within two calendar years after the filing date under § 516.45, OTS will notify...

  17. 12 CFR 516.290 - What will happen if OTS does not approve or disapprove my application within two calendar years...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... disapprove my application within two calendar years after the filing date? 516.290 Section 516.290 Banks and... within two calendar years after the filing date? (a) Withdrawal. If OTS has not approved or denied your pending application within two calendar years after the filing date under § 516.45, OTS will notify...

  18. Genome Sequence of Desulfosporosinus sp. OT, an Acidophilic Sulfate-Reducing Bacterium from Copper Mining Waste in Norilsk, Northern Siberia

    PubMed Central

    Abicht, Helge K.; Mancini, Stefano; Karnachuk, Olga V.; Solioz, Marc

    2011-01-01

    We have sequenced the genome of Desulfosporosinus sp. OT, a Gram-positive, acidophilic sulfate-reducing Firmicute isolated from copper tailing sediment in the Norilsk mining-smelting area in Northern Siberia, Russia. This represents the first sequenced genome of a Desulfosporosinus species. The genome has a size of 5.7 Mb and encodes 6,222 putative proteins. PMID:21994931

  19. 75 FR 10560 - Application for Conversion From: (a) OTS-Regulated, State-Chartered Savings Association to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-08

    ... Association to Federal Savings Association; (b) National Bank, Commercial Bank, State Savings Bank, or Credit Union to Federal Savings Association; (c) State Mutual Holding Company to a Federal Mutual Holding Company AGENCY: Office of Thrift Supervision (OTS), Treasury. ACTION: Notice and request for comment...

  20. 12 CFR 502.26 - How does OTS calculate the semi-annual assessment for savings and loan holding companies?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...-site supervision of a noncomplex, low risk savings and loan holding company structure. OTS will... savings and loan holding companies: a component based on the risk or complexity of the savings and loan holding company's business, a component based on its organizational form, and a component based on...

  1. Genome sequence of Desulfosporosinus sp. OT, an acidophilic sulfate-reducing bacterium from copper mining waste in Norilsk, Northern Siberia.

    PubMed

    Abicht, Helge K; Mancini, Stefano; Karnachuk, Olga V; Solioz, Marc

    2011-11-01

    We have sequenced the genome of Desulfosporosinus sp. OT, a Gram-positive, acidophilic sulfate-reducing Firmicute isolated from copper tailing sediment in the Norilsk mining-smelting area in Northern Siberia, Russia. This represents the first sequenced genome of a Desulfosporosinus species. The genome has a size of 5.7 Mb and encodes 6,222 putative proteins.

  2. Correction to ATel 10150: New OT is PTSS-17jdx deteted on 2017-03-07.727524 UT

    NASA Astrophysics Data System (ADS)

    Li, Bin

    2017-03-01

    We report a correction to the time of detection of new OT PTSS-17jdx in ATel #10150. The time of detection is 2017-03-07.727524 UT but not 2017-02-07.727524 UT. More interesting information can be found on PTSS . We apologize for any confusion caused by this typo error.

  3. Purification, crystallization and preliminary crystallographic analysis of the biotin–protein ligase from Pyrococcus horikoshii OT3

    SciTech Connect

    Bagautdinov, Bagautdin; Kuroishi, Chizu; Sugahara, Mitsuaki; Kunishima, Naoki

    2005-02-01

    The biotin–protein ligase from P. horikoshii OT3 was overexpressed, purified, crystallized and cocrystallized with biotin, ADP and biotinyl-5′-AMP. The crystals belong to space group P2{sub 1} and diffract to beyond 1.6 Å resolution.

  4. Spectroscopic Classification of AT2016axw (=MASTER OT J142718.40-014031.0 =PS16axi)

    NASA Astrophysics Data System (ADS)

    Blanchard, Peter; Berger, Edo; Bieryla, Allyson; Brzycki, Bryan; Cohn, Amy; Dillett, Sean; Feder-Staehle, Richard; Frostig, Danielle; Grell, Gabe; James, Nicholas; Johnson, April; Mahmood, Zahra; Merryman, Hunter; Peak, Barra; Sanders, Cecilia; Taylor, Anthony

    2016-03-01

    We obtained a low-resolution optical spectrum of AT2016axw (=MASTER OT J142718.40-014031.0 =PS16ayd; ATel #8791). Observations were carried out on 2016 March 16.4 UT using the FAST spectrograph mounted on the F.L. Whipple Observatory 1.5-m telescope.

  5. Spectroscopic Classification of MASTER OT J152333.04+092125.6 as a post-maximum Type Ia Supernova

    NASA Astrophysics Data System (ADS)

    Kilpatrick, Charles; Andrews, Jennifer; Milne, Peter; Smith, Nathan

    2016-04-01

    The AZTEC (Arizona Transient Exploration and Characterization) collaboration reports an optical spectrum of MASTER OT J152333.04+092125.6 (ATEL #8903) obtained on UT 2016 Apr. 27.440 with the 2.3m Bok telescope (+ Boller & Chivens spectrograph) on Kitt Peak, Arizona.

  6. 75 FR 63107 - Alternatives to the Use of External Credit Ratings in the Regulations of the OTS

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-14

    ... market instrument and any references to or requirements in regulations regarding credit ratings. The... security or money market instrument; and (2) any references to or requirements in such regulations... sound investment securities practices. OTS expects savings associations to understand the price...

  7. Theileria sp. OT3 and other tick-borne pathogens in sheep and ticks in Italy: molecular characterization and phylogeny.

    PubMed

    Giangaspero, A; Marangi, M; Papini, R; Paoletti, B; Wijnveld, M; Jongejan, F

    2015-02-01

    PCR Reverse Line Blot (RLB) hybridization and sequencing were used to determine the dynamics of infection with tick-borne pathogens in one hundred apparently healthy sheep in Italy. Blood samples were tested once prior to the onset of the grazing season (June 2010) and once after the end of the grazing season (August 2010). Ticks collected from sheep and from the vegetation were also tested by PCR/RLB. Before grazing, 56% of the sheep harbored several tick-borne pathogens: Anaplasma ovis was the most prevalent (41%), followed by A. ovis co-infected with Theileria sp. OT3 (14%). After grazing, 87% of sheep were positive for A. ovis alone (41%), co-infected with Theileria sp. OT3 (8%) or co-infected with Babesia motasi (5%). Other sheep were infected with Anaplasma phagocytophilum alone (20%), co-infected with B. motasi (7%) or with Theileria sp. OT3 (5%) (p<0.001). After grazing, sheep were significantly more infected with tick-borne pathogens than before grazing. Ticks collected were all Haemaphysalis punctata (n-89) and 36% were positive for A. ovis, Ehrlichia ovina and A. ovis combined with A. phagocytophilum. Phylogenetic analysis including isolates from countries in the Mediterranean Basin show circulation of the same variants of Theileria sp. OT3, whereas two different geographical origins for the isolates of A. ovis and A. phagocytophilum were identified. This is the first report from Italy of Theileria sp. OT3 in sheep, whereas the detection of Ehrlichia ovina in ticks is worth noting, and the presence of A. phagocytophilum in sheep and in ticks poses a potential public health risk.

  8. A new microRNA signal pathway regulated by long noncoding RNA TGFB2-OT1 in autophagy and inflammation of vascular endothelial cells

    PubMed Central

    Huang, ShuYa; Lu, Wei; Ge, Di; Meng, Ning; Li, Ying; Su, Le; Zhang, ShangLi; Zhang, Yun; Zhao, BaoXiang; Miao, JunYing

    2015-01-01

    TGFB2-OT1 (TGFB2 overlapping transcript 1) is a newly discovered long noncoding RNA (lncRNA) derived from the 3′UTR of TGFB2. It can regulate autophagy in vascular endothelial cells (VECs). However, the mechanisms of TGFB2-OT1 action are unclear, and whether it is involved in VECs dysfunction needs investigation. Here, the level of TGFB2-OT1 was markedly increased by lipopolysaccharide and oxidized low-density lipoprotein, 2 VECs inflammation triggers. A chemical small molecule, 3-benzyl-5-((2-nitrophenoxy) methyl)-dihydrofuran-2(3H)-one (3BDO) significantly decreased TGFB2-OT1 levels and inhibited the effect of LPS and oxLDL. The NUPR1 level was upregulated by the 2 inflammation inducers and modulated the TGFB2-OT1 level by promoting the expression of TIA1, responsible for TGFB2-OT1 processing. We focused on how TGFB2-OT1 regulated autophagy and inflammation. Use of miRNA chip assay, TGFB2-OT1 overexpression technology and 3BDO revealed that TGFB2-OT1 regulated the levels of 3 microRNAs, MIR3960, MIR4488 and MIR4459. Further studies confirmed that TGFB2-OT1 acted as a competing endogenous RNA, bound to MIR3960, MIR4488 and MIR4459, then regulated the expression of the miRNA targets CERS1 (ceramide synthase 1), NAT8L (N-acetyltransferase 8-like [GCN5-related, putative]), and LARP1 (La ribonucleoprotein domain family, member 1). CERS1 and NAT8L participate in autophagy by affecting mitochondrial function. TGFB2-OT1 increased the LARP1 level, which promoted SQSTM1 (sequestosome 1) expression, NFKB RELA and CASP1 activation, and then production of IL6, IL8 and IL1B in VECs. Thus, NUPR1 and TIA1 may control the level of TGFB2-OT1, and TGFB2-OT1 bound to MIR3960, MIR4488 and MIR4459, which targeted CERS1, NAT8L, and LARP1, respectively, the key proteins involved in autophagy and inflammation. PMID:26565952

  9. Effect of Ozone Therapy (OT) on Healing of Colonic Anastomosis in a Rat Model of Peritonitis

    PubMed Central

    Erginel, Başak; Erginel, Turgay; Aksoy, Bilgin; Dokucu, Ali İhsan

    2014-01-01

    Background: Ozone is a three-oxygen molecule (O3). Ozone therapy (OT) is systematically effective when pathological inflammatory and immunologic processes are activated. Among of these conditions are wound healing, macular degeneration related to aging, and conditions that are ischemic or infectious. Aims: The aim of this study was to determine the effects of OT on wound healing of intestinal anastomosis in the presence of peritonitis in a rat model. Study Design: Animal experimentation. Methods: A total of 40 Wistar albino rats were randomized into four groups (n=10) including: sham (S), peritonitis (P), ozone 0 (O0), and ozone 24 (O24). In group S, only cecal dissection was carried out. The S group had only a cecal dissection and intestinal anastomosis performed, but no peritonitis. In all other groups, cecal ligation and puncture (CLP) followed the cecal dissection to induce bacterial peritonitis. 24 h after puncture, a cecal resection and ileocolic anastomosis were performed. In group P, 24 h after CLP, a cecal resection and ileocolic anastomosis were performed and no ozone was administered. In group O0, immediately after the anastomosis, and in group O24, starting 24 hours after the anastomosis, an intraperitoneal 1 mg/kg/day ozone administration was applied for seven days. On the seventh day the animals were sacrificed, the anastomotic bursting pressures (BP) and the hydroxyproline values of the anastomotic tissues were measured, and histopathologic examination of the anastomotic segment was carried out. Results: The highest BP was in group S, with 211±23.13 mmHg. The mean BP of group P was 141±56.25 mmHg, which was significantly lower than in the other two peritonitis groups that received ozone therapy, group O0 and O24, where it was 192±22 and 166±45 mmHg, respectively (p<0.05). The difference in the BP between groups O0 and O24 was not statistically significant (p>0.05). Histopathologic analyses of the anastomotic segments determined there was

  10. An AFM Study of the Effects of Silanization Temperature, Hydration, and Annealing on the Nucleation and Aggregation of Condensed OTS Domains on Mica.

    PubMed

    Britt, David W; Hlady, Vladimir

    1996-03-25

    Partial monolayers of octadecyltrichlorosilane (OTS) were formed on mica under different reaction conditions in which the silanization temperature, time, and amount of water adsorbed on the mica substrates were varied. OTS surface coverage increased with silanization time for all samples; however, the amount and distribution of adsorbed OTS varied greatly under these different reaction conditions. AFM analysis showed that OTS formed two phases on mica silanized at 25°C: condensed "island-like" domains and expanded "liquid-like" domains. Partially dehydrated mica silanized at 9°C, however, displayed only condensed domains which were of smaller size compared to those on the 25°C samples. The lateral diffusion and aggregation of small condensed OTS domains to form larger aggregates was evident on all surfaces except the 25°C partially dehydrated mica. A uniform distribution of many small condensed domains surrounded by expanded OTS phases was seen instead. Extended annealing resulted in surface diffusion and aggregation of these domains and nucleation of new condensed domains from the surrounding expanded OTS phases. These observations are consistent with a deposition, diffusion, and aggregation model (DDA) which allows for activated diffusion; however, rigorous modeling is not presented here.

  11. Over-Expression of the Mycobacterial Trehalose-Phosphate Phosphatase OtsB2 Results in a Defect in Macrophage Phagocytosis Associated with Increased Mycobacterial-Macrophage Adhesion

    PubMed Central

    Li, Hao; Wu, Mei; Shi, Yan; Javid, Babak

    2016-01-01

    Trehalose-6-phosphate phosphatase (OtsB2) is involved in the OtsAB trehalose synthesis pathway to produce free trehalose and is strictly essential for mycobacterial growth. We wished to determine the effects of OtsB2 expression on mycobacterial phenotypes such as growth, phagocytosis and survival in macrophages. Mycobacterium bovis-bacillus calmette-guerin (BCG) over-expressing OtsB2 were able to better survive in stationary phase. Over-expression of OtsB2 led to a decrease in phagocytosis but not survival in THP-1 macrophage-like cells, and this was not due to a decrease in general macrophage phagocytic activity. Surprisingly, when we investigated macrophage–mycobacterial interactions by flow cytometry and atomic force microscopy, we discovered that BCG over-expressing OtsB2 have stronger binding to THP-1 cells than wild-type BCG. These results suggest that altering OtsB2 expression has implications for mycobacterial host–pathogen interactions. Macrophage–mycobacteria phagocytic interactions are complex and merit further study. PMID:27867377

  12. Isolation and Pharmacological Characterization of α-Elapitoxin-Ot1a, a Short-Chain Postsynaptic Neurotoxin from the Venom of the Western Desert Taipan, Oxyuranus temporalis

    PubMed Central

    Barber, Carmel M.; Ahmad Rusmili, Muhamad Rusdi; Hodgson, Wayne C.

    2016-01-01

    Taipans (Oxyuranus spp.) are elapids with highly potent venoms containing presynaptic (β) and postsynaptic (α) neurotoxins. O. temporalis (Western Desert taipan), a newly discovered member of this genus, has been shown to possess venom which displays marked in vitro neurotoxicity. No components have been isolated from this venom. We describe the characterization of α-elapitoxin-Ot1a (α-EPTX-Ot1a; 6712 Da), a short-chain postsynaptic neurotoxin, which accounts for approximately 30% of O. temporalis venom. α-Elapitoxin-Ot1a (0.1–1 µM) produced concentration-dependent inhibition of indirect-twitches, and abolished contractile responses to exogenous acetylcholine and carbachol, in the chick biventer cervicis nerve-muscle preparation. The inhibition of indirect twitches by α-elapitoxin-Ot1a (1 µM) was not reversed by washing the tissue. Prior addition of taipan antivenom (10 U/mL) delayed the neurotoxic effects of α-elapitoxin-Ot1a (1 µM) and markedly attenuated the neurotoxic effects of α-elapitoxin-Ot1a (0.1 µM). α-Elapitoxin-Ot1a displayed pseudo-irreversible antagonism of concentration-response curves to carbachol with a pA2 value of 8.02 ± 0.05. De novo sequencing revealed the main sequence of the short-chain postsynaptic neurotoxin (i.e., α-elapitoxin-Ot1a) as well as three other isoforms found in O. temporalis venom. α-Elapitoxin-Ot1a shows high sequence similarity (i.e., >87%) with other taipan short-chain postsynaptic neurotoxins. PMID:26938558

  13. The luminous red nova M101-OT2015-1: a candidate for common envelope ejection

    NASA Astrophysics Data System (ADS)

    Blagorodnova, Nadejda; Kasliwal, Mansi M.; Kotak, Rubina

    2017-01-01

    Binary interaction is an important phase in the study of stellar evolution. Approximately 50% of O star population live in close binary systems as to allow interaction with the companion. Although massive binary progenitors have been associated with thermonuclear supernovae, stripped core collapse supernovae, cataclysmic variables, X-ray binaries, or the mind blowing massive binary black holes recently detected by LIGO, the exact evolutionary path followed by the system is still under debate. One of the critical phases is the common envelope (CE) phase, required to bring a long period binary into a much shorter orbit. Currently, this phase also represents a challenge for the current stellar evolution models. Given the uncertainty, observational constraints are valuable input to advance in this field. One particular class of transient objects, called Luminous Red Novae (LRNe), has been associated with the termination of the CE phase, when a total or partial ejection of the least bound layers of the primary star are expelled at the expense of decreasing the orbital energy of the system. In my talk I will discuss the results of 16 years of observations of M101-OT2015-1, a LRN in M101 galaxy. I will describe the progenitor star (system) and the main characteristics of the outburst. Finally, I will present the results of the evolution of its remnant in infrared wavelengths. Given the long time span of our observations, this event represents one of the best studied CE ejection candidate at extragalactic distances.

  14. Almost gone: SN 2008S and NGC 300 2008OT-1 are fainter than their progenitors

    NASA Astrophysics Data System (ADS)

    Adams, S. M.; Kochanek, C. S.; Prieto, J. L.; Dai, X.; Shappee, B. J.; Stanek, K. Z.

    2016-08-01

    We present late-time Hubble and Spitzer Space Telescope (SST) imaging of SN 2008S and NGC 300 2008OT-1, the prototypes of a common class of stellar transients whose true nature is debated. Both objects are still fading and are now >15 times fainter than their progenitors in the mid-IR and are undetected in the optical and near-IR. Data from the Large Binocular Telescope and Magellan show that neither source has been variable in the optical since fading in 2010. We present models of surviving sources obscured by dusty shells or winds and find that extreme dust models are needed for surviving stars to be successfully hidden by dust, which suggests that these transients may be genuine, but low-energy, supernova explosions. Though SN 2008S is not detected in Chandra X-Ray Observatory data taken in 2012, the flux limits allow the fading IR source to be powered solely by the shock interaction of ejecta with the circumstellar medium if the shock velocity at the time of the observation was ≳20 per cent slower than estimated from emission line widths while the transient was still optically bright. Continued SST monitoring and 10-20 μm observations with James Webb Space Telescope can resolve any remaining ambiguities.

  15. Enhancement of the skin permeation of clindamycin phosphate by Aerosol OT/1-butanol microemulsions.

    PubMed

    Junyaprasert, Varaporn Buraphacheep; Boonsaner, Panee; Leatwimonlak, Sujitra; Boonme, Prapaporn

    2007-08-01

    Microemulsions of water/isopropyl palmitate (IPP)/Aerosol OT (AOT)/1-butanol were developed as alternative formulations for topical delivery of clindamycin phosphate. Effect of AOT:1-butanol ratios on microemulsion region existence in the pseudoternary phase diagrams was investigated. The 2:1 AOT:1-butanol provided the largest microemulsion region. Five microemulsions of 1% w/w clindamycin phosphate were prepared and characterized. The permeation through human epidermis of the microemulsions was evaluated and compared with the 70% isopropanol solution using modified Franz diffusion cells. The drug permeation from all microemulsions was found to be significantly greater than that from the solution, indicating the enhancement of the skin permeation by the microemulsions. Within the same microemulsion type, the drug permeation increased with increasing the amount of AOT:1-butanol. The drug permeation from oil-in-water (o/w) microemulsions was relatively higher than that from water-in-oil (w/o) microemulsions. In addition, all microemulsions were stable for at least three months at 30 +/- 1 degrees C.

  16. MASTER OT J130845.02-323254.9: Variable Stars as Source of the High Energy Neutrino.

    NASA Astrophysics Data System (ADS)

    Lipunov, V.; Tyurina, N.; Gorbovskoy, E.; Buckley, D.

    2016-09-01

    As reported in ATel #9425 Global MASTER Net auto-detection system ( ( Lipunov et al., MASTER Global Robotic Net, Advances in Astronomy, 2010, 30L) discovered OT source at (RA, Dec) = 13h 08m 45.02s -32d 32m 54.9s on 2016-08-24.73811 UT during inspection of HESE IceCube alert (14 August 2016, 58537957 trigger number http://gcn.gsfc.nasa.gov/notices_amon/58537957_128340.amon , Dornic et al. ATEL #9440 ). MASTER-SAAO auto-detection system detected again OT at RA (2000) = 13 08 45.02 -32 32 54.9 on 2016-09-04.7627UT (ATEL #9425).

  17. Partial KCNQ1OT1 hypomethylation: A disguised familial Beckwith–Wiedemann syndrome as a sporadic adrenocortical tumor

    PubMed Central

    H'mida Ben-Brahim, Dorra; Hammami, Sabeur; Haddaji Mastouri, Marwa; Trabelsi, Saoussen; Chourabi, Maroua; Sassi, Sihem; Mougou, Soumaya; Gribaa, Moez; Zakhama, Abdelfattah; Guédiche, Mohamed Neji; Saad, Ali

    2014-01-01

    Beckwith–Wiedemann syndrome has a wide spectrum of complications such as embryonal tumors, namely adrenocortical tumor. Tumor predisposition is one of the most challenging manifestations of this syndrome. A 45-day old female with a family history of adrenocortical tumor presented with adrenocortical tumor. The case raised suspicion of a hereditary Beckwith–Wiedemann syndrome, therefore molecular analysis was undertaken. The results revealed partial KCNQ1OT1 hypomethylation in the infant's blood DNA which was associated with a complete loss of methylation in the infant's adrenocortical tumor tissue. It is unique for familial Beckwith–Wiedemann syndrome caused by KCNQ1OT1 partial hypomethylation to manifest solely through adrenocortical tumor. Incomplete penetrance and specific tissue mosaicism could provide explanations to this novel hereditary Beckwith–Wiedemann syndrome presentation. PMID:26937341

  18. Prognostic value of lncRNA SOX2OT for Chinese cancer patients: A meta-analysis.

    PubMed

    Jing, Xuran; Lin, Jieru; Wang, Hongwei; Tian, Liyuan; Tian, Runhua; Zhang, Yunyuan; Chen, Xian; Zhang, Jinyu

    2017-01-01

    SOX2OT has been demonstrated to be aberrantly expressed in several types of cancer and maybe serve as a prognostic marker for cancer patients. However, most individual studies have been limited by small sample sizes and controversial results. Therefore, the present meta-analysis was conducted to analyze available data to reveal the potential clinical application of SOX2OT on cancer prognosis, tumor progression, distance metastasis and lymph node metastasis. Up to February 20, 2017, literature collections were conducted by comprehensive searching electronic databases, including Cochrane Library, PubMed, Embase, BioMed Central, Springer, ScienceDirect, ISI Web of Knowledge, together with three Chinese databases: China National Knowledge Internet (CNKI), Weipu and Wanfang. The hazard ratios (HR) with 95% confidence interval (95% CI) were calculated to assess the strength of the association. Five studies with a total of 481 cancer patients were included in the present meta-analysis. The results indicated that elevated SOX2OT significantly predicted unfavorable overall survival (OS) (HR = 2.44, 95% CI: 1.75-3.39, P<0.0001) and tumor progression (III/IV vs. I/II: HR 1.62, 95%CI: 1.30-2.02, P<0.0001), but failed to predict distant metastasis (HR: 3.30, 95%CI: 0.74-14.61, P = 0.12) and lymph node metastasis (HR: 1.29, 95% CI: 0.87-1.91, P = 0.21). The results revealed that SOX2OT expression level was an independent prognostic biomarker for OS and tumor progression in Chinese cancer patients.

  19. Limited Production (LP) Precision Runway Monitor (PRM) Operational Test and Evaluation integration and OT and E Operational Test Plan

    NASA Astrophysics Data System (ADS)

    Livings, Jeffrey

    1995-05-01

    This document defines the Test Plan and corresponding Test Verification Requirements Traceability Matrix (TVRTM) that will be used to conduct the Limited Production (LP) Precision Runway Monitor (PRM) Operational Test and Evaluation (OT and E) Integration and OT and E Operational tests. These tests will be conducted at the Minneapolis-St. Paul International Airport following the Contractor Site Acceptance Test. The LP PRM OT and E test effort will concentrate on Operational Effectiveness and Suitability. The Operational Effectiveness Test consists of a review of the contractor performed Development Test and Evaluation (DT and E) and Site Acceptance Tests. This review will evaluate whether each of the Measures of Effectiveness had been satisfactorily tested and whether the results meet the Minimum Acceptable Operational REquirements MAORs). This review will be conducted solely by test engineers and does not require the PRM system. The Operational Suitability Tests will expose the test participants (Air Traffic (AT) Controllers and Airway Facilities (AF) Technicians) to the PRM system in an operational environment while they perform specified operational procedures. These tests will be conducted in two separate phases: AT Suitability and AF Suitability. Each of these phases is focused on the specific test participants.

  20. VizieR Online Data Catalog: Follow-up photometry of M101 OT2015-1 (Blagorodnova+, 2017)

    NASA Astrophysics Data System (ADS)

    Blagorodnova, N.; Kotak, R.; Polshaw, J.; Kasliwal, M. M.; Cao, Y.; Cody, A. M.; Doran, G. B.; Elias-Rosa, N.; Fraser, M.; Fremling, C.; Gonzalez-Fernandez, C.; Harmanen, J.; Jencson, J.; Kankare, E.; Kudritzki, R.-P.; Kulkarni, S. R.; Magnier, E.; Manulis, I.; Masci, F. J.; Mattila, S.; Nugent, P.; Ochner, P.; Pastorello, A.; Reynolds, T.; Smith, K.; Sollerman, J.; Taddia, F.; Terreran, G.; Tomasella, L.; Turatto, M.; Vreeswijk, P. M.; Wozniak, P.; Zaggia, S.

    2017-07-01

    The location of M101-OT2015-1 has been serendipitously imaged by numerous telescopes and instruments over the last 15 years (from 2000 to 2015). Our best quality pre-discovery image (seeing of 0.55") is an r-band exposure at -3625 days pre-peak from the Canada-France-Hawaii Telescope (CFHT). The historical optical data for M101-OT was retrieved from the CFHT MegaPrime and CFHT12K/Mosaic, using single and combined exposures, Pan-STARRS-1/GPC1 (PS1), Isaac Newton Telescope/Wide Field Camera (INT/WFC), and Sloan Digital Sky Survey (SDSS) DR 10 (Ahn+ 2014, see V/147). Unfortunately, there are no HST images covering the location of the source. Post-discovery optical magnitudes were obtained from the reported followup astronomer's telegrams (ATels), Liverpool Telescope (LT), the Nordic Optical Telescope (NOT), and the Palomar P48 and P60 telescopes. The infrared data were retrieved from CFHT/WIRCam, UKIRT/WFCAM, and the Spitzer Infrared Array Camera in 3.6 and 4.5um as part of the SPitzer InfraRed Intensive Transients Survey (SPIRITS) (Kasliwal+, 2017ApJ...839...88K). Details of pre-discovery photometry and post-discovery optical photometry may be found in the Appendices Tables 1 and 2, respectively. We obtained spectra of M101-OT using a range of facilities in 2015 Feb-Jul. (3 data files).

  1. Impaired Memory in OT-II Transgenic Mice Is Associated with Decreased Adult Hippocampal Neurogenesis Possibly Induced by Alteration in Th2 Cytokine Levels.

    PubMed

    Jeon, Seong Gak; Kim, Kyoung Ah; Chung, Hyunju; Choi, Junghyun; Song, Eun Ji; Han, Seung-Yun; Oh, Myung Sook; Park, Jong Hwan; Kim, Jin-Il; Moon, Minho

    2016-08-31

    Recently, an increasing number of studies have focused on the effects of CD4+ T cell on cognitive function. However, the changes of Th2 cytokines in restricted CD4+ T cell receptor (TCR) repertoire model and their effects on the adult hippocampal neurogenesis and memory are not fully understood. Here, we investigated whether and how the mice with restricted CD4+ repertoire TCR exhibit learning and memory impairment by using OT-II mice. OT-II mice showed decreased adult neurogenesis in hippocampus and short- and long- term memory impairment. Moreover, Th2 cytokines in OT-II mice are significantly increased in peripheral organs and IL-4 is significantly increased in brain. Finally, IL-4 treatment significantly inhibited the proliferation of cultured adult rat hippocampal neural stem cells. Taken together, abnormal level of Th2 cytokines can lead memory dysfunction via impaired adult neurogenesis in OT-II transgenic.

  2. Impaired Memory in OT-II Transgenic Mice Is Associated with Decreased Adult Hippocampal Neurogenesis Possibly Induced by Alteration in Th2 Cytokine Levels

    PubMed Central

    Jeon, Seong Gak; Kim, Kyoung Ah; Chung, Hyunju; Choi, Junghyun; Song, Eun Ji; Han, Seung-Yun; Oh, Myung Sook; Park, Jong Hwan; Kim, Jin-il; Moon, Minho

    2016-01-01

    Recently, an increasing number of studies have focused on the effects of CD4+ T cell on cognitive function. However, the changes of Th2 cytokines in restricted CD4+ T cell receptor (TCR) repertoire model and their effects on the adult hippocampal neurogenesis and memory are not fully understood. Here, we investigated whether and how the mice with restricted CD4+ repertoire TCR exhibit learning and memory impairment by using OT-II mice. OT-II mice showed decreased adult neurogenesis in hippocampus and short- and long- term memory impairment. Moreover, Th2 cytokines in OT-II mice are significantly increased in peripheral organs and IL-4 is significantly increased in brain. Finally, IL-4 treatment significantly inhibited the proliferation of cultured adult rat hippocampal neural stem cells. Taken together, abnormal level of Th2 cytokines can lead memory dysfunction via impaired adult neurogenesis in OT-II transgenic. PMID:27432189

  3. Multiseasonal Tree Crown Structure Mapping with Point Clouds from OTS Quadrocopter Systems

    NASA Astrophysics Data System (ADS)

    Hese, S.; Behrendt, F.

    2017-08-01

    OTF (Off The Shelf) quadro copter systems provide a cost effective (below 2000 Euro), flexible and mobile platform for high resolution point cloud mapping. Various studies showed the full potential of these small and flexible platforms. Especially in very tight and complex 3D environments the automatic obstacle avoidance, low copter weight, long flight times and precise maneuvering are important advantages of these small OTS systems in comparison with larger octocopter systems. This study examines the potential of the DJI Phantom 4 pro series and the Phantom 3A series for within-stand and forest tree crown 3D point cloud mapping using both within stand oblique imaging in different altitude levels and data captured from a nadir perspective. On a test site in Brandenburg/Germany a beach crown was selected and measured with 3 different altitude levels in Point Of Interest (POI) mode with oblique data capturing and deriving one nadir mosaic created with 85/85 % overlap using Drone Deploy automatic mapping software. Three different flight campaigns were performed, one in September 2016 (leaf-on), one in March 2017 (leaf-off) and one in May 2017 (leaf-on) to derive point clouds from different crown structure and phenological situations - covering the leaf-on and leafoff status of the tree crown. After height correction, the point clouds where used with GPS geo referencing to calculate voxel based densities on 50 × 10 × 10 cm voxel definitions using a topological network of chessboard image objects in 0,5 m height steps in an object based image processing environment. Comparison between leaf-off and leaf-on status was done on volume pixel definitions comparing the attributed point densities per volume and plotting the resulting values as a function of distance to the crown center. In the leaf-off status SFM (structure from motion) algorithms clearly identified the central stem and also secondary branch systems. While the

  4. Unique effects of aerosol OT lamellar structures on the dynamics of guest molecules.

    PubMed

    De, Dipanwita; Datta, Anindya

    2013-06-25

    The behavior of lamellar structures of Aerosol OT (AOT) as hosts, vis-à-vis the flexible normal micelles and rigid nanochannels of Nafion membranes, has been investigated with two different fluorophores, [2,2'-bipyridyl]-3,3'-diol (BP(OH)2) and coumarin 102 (C102). Surprisingly, for BP(OH)2, a rise time is observed at intermediate emission wavelengths and not in the red edge of the fluorescence spectrum. A shoulder at 525 nm is observed in time resolved emission spectra (TRES) at initial times of BP(OH)2 in AOT lamellar structures. This feature is the signature of the monoketo (MK) tautomer, observed for the first time in a microheterogeneous medium. Also, the usually ultrafast single proton transfer in BP(OH)2 is retarded to an considerable extent in lamellar structures. The potential of this medium in promoting unusual intermediates is thus highlighted. This property may be ascribed to the rigidity of lamellar structures, compared to hosts such as regular micelles. However, studies using another fluorophore, coumarin 102 (C102), brings out the fact that these structures are significantly different from the rigid host, Nafion, as well. The absence of excited state proton transfer (ESPT) in this molecule in AOT lamellar structures indicates that it is not protonated, unlike in Nafion. Thus, the interfacial pH of lamellar structures is found to be significantly greater than that of Nafion nanochannels. From the time dependent Stokes shift (TDSS) of the emission spectra of C102, the relaxation time (0.85 ns) of interfacial water in lamellar structures is found to be an order of magnitude faster than that observed in Nafion nanochannels, in which H3O(+) ions have been substituted by different cations. Hence, this study demonstrates that AOT lamellar structures are rather unique hosts and that they behave very differently from conventional rigid and flexible hosts such as normal micelles and Nafion, respectively.

  5. Molecular simulation study of water mobility in aerosol-OT reverse micelles.

    PubMed

    Chowdhary, Janamejaya; Ladanyi, Branka M

    2011-06-16

    In this work, we present results from molecular dynamics simulations on the single-molecule relaxation of water within reverse micelles (RMs) of different sizes formed by the surfactant aerosol-OT (AOT, sodium bis(2-ethylhexyl)sulfosuccinate) in isooctane. Results are presented for RM water content w(0) = [H(2)O]/[AOT] in the range from 2.0 to 7.5. We show that translational diffusion of water within the RM can, to a good approximation, be decoupled from the translation of the RM through the isooctane solvent. Water translational mobility within the RM is restricted by the water pool dimensions, and thus, the water mean-squared displacements (MSDs) level off in time. Comparison with models of diffusion in confined geometries shows that a version of the Gaussian confinement model with a biexponential decay of correlations provides a good fit to the MSDs, while a model of free diffusion within a sphere agrees less well with simulation results. We find that the local diffusivity is considerably reduced in the interfacial region, especially as w(0) decreases. Molecular orientational relaxation is monitored by examining the behavior of OH and dipole vectors. For both vectors, orientational relaxation slows down close to the interface and as w(0) decreases. For the OH vector, reorientation is strongly affected by the presence of charged species at the RM interface and these effects are especially pronounced for water molecules hydrogen-bonded to surfactant sites that serve as hydrogen-bond acceptors. For the dipole vector, orientational relaxation near the interface slows down more than that for the OH vector due mainly to the influence of ion-dipole interactions with the sodium counterions. We investigate water OH and dipole reorientation mechanisms by studying the w(0) and interfacial shell dependence of orientational time correlations for different Legendre polynomial orders.

  6. Knockdown of Long Non-Coding RNA KCNQ1OT1 Restrained Glioma Cells’ Malignancy by Activating miR-370/CCNE2 Axis

    PubMed Central

    Gong, Wei; Zheng, Jian; Liu, Xiaobai; Liu, Yunhui; Guo, Junqing; Gao, Yana; Tao, Wei; Chen, Jiajia; Li, Zhiqing; Ma, Jun; Xue, Yixue

    2017-01-01

    Accumulating evidence has highlighted the potential role of long non-coding RNAs (lncRNAs) as biomarkers and therapeutic targets in solid tumors. Here, we elucidated the function and possible molecular mechanisms of lncRNA KCNQ1OT1 in human glioma U87 and U251 cells. Quantitative Real-Time polymerase chain reaction (qRT-PCR) demonstrated that KCNQ1OT1 expression was up-regulated in glioma tissues and cells. Knockdown of KCNQ1OT1 exerted tumor-suppressive function in glioma cells. Moreover, a binding region was confirmed between KCNQ1OT1 and miR-370 by dual-luciferase assays. qRT-PCR showed that miR-370 was down-regulated in human glioma tissue and cells. In addition, restoration of miR-370 exerted tumor-suppressive function via inhibiting cell proliferation, migration and invasion, while promoting the apoptosis of human glioma cells. Knockdown of KCNQ1OT1 decreased the expression level of Cyclin E2 (CCNE2) by binding to miR-370. Further, miR-370 bound to CCNE2 3′UTR region and decreased the expression of CCNE2. These results provided a comprehensive analysis of KCNQ1OT1-miR-370-CCNE2 axis in human glioma cells and might provide a novel strategy for glioma treatment. PMID:28381990

  7. Fluorescent behavior of B-phycoerythrin in microemulsions of aerosol OT/water/isooctane.

    PubMed

    Bermejo, Ruperto; Tobaruela, Diego J; Talavera, Eva M; Orte, Angel; Alvarez-Pez, Jose M

    2003-07-15

    Taking advantage of its unusual fluorescent properties, the incorporation of B-phycoerythrin (B-PE) in aerosol OT (AOT, sodium bis-(2-ethylhexyl) sulphosuccinate)/water/isooctane microemulsions was investigated by following their steady-state and time-resolved fluorescence as a function of the water-to-surfactant molar ratio, w(0). The fluorescent intensity at 575 nm increased continuously with increasing water content, saturating at a w(0) around 35 and staying practically constant at w(0)> or =40. The steady-state anisotropy showed an initial increase with increasing water content until w(0)=23 and then decreased strongly, staying practically constant when w(0)> or =40. The values of the fluorescent parameters, anisotropy and fluorescent intensity, were unchanged when the water content of the system increased in the range between w(0)=40 to 50. This implies the effective incorporation of B-PE in the microemulsion droplets with w(0)> or =40, as well as the equilibrium of the dispersion at these water/surfactant ratios, since higher water content does not affect the main surrounding microenvironment of the protein. The overall incorporation in the microemulsion droplets caused minor spectroscopic changes with respect to biliprotein in aqueous solution of 20 mM sodium phosphate buffer, pH 7.0, such as a blue absorption shift of 3 nm and an emission shift of 1.5 nm, as well as a slight increase in excitation anisotropy spectrum mainly caused by a decrease in protein mobility. Therefore, there are no important interactions between the chromophores and the AOT sulfonate head groups. Emission intensity decays followed complex kinetics in both aqueous and dispersion media. The stability with time and temperature of the biliprotein in the microemulsion was higher than in the aqueous solution. All the results can be explained in terms of B-PE inclusion in the water droplets of AOT microemulsions where the protein has similar configuration and conformation to that in

  8. Characterization of the archaeal ribonuclease P proteins from Pyrococcus horikoshii OT3.

    PubMed

    Terada, Atsushi; Honda, Takashi; Fukuhara, Hideo; Hada, Kazumasa; Kimura, Makoto

    2006-08-01

    Ribonuclease P (RNase P) is a ribonucleoprotein complex involved in the processing of the 5'-leader sequence of precursor tRNA (pre-tRNA). Our earlier study revealed that RNase P RNA (pRNA) and five proteins (PhoPop5, PhoRpp38, PhoRpp21, PhoRpp29, and PhoRpp30) in the hyperthermophilic archaeon Pyrococcus horikoshii OT3 reconstituted RNase P activity that exhibits enzymatic properties like those of the authentic enzyme. In present study, we investigated involvement of the individual proteins in RNase P activity. Two particles (R-3Ps), in which pRNA was mixed with three proteins, PhoPop5, PhoRpp30, and PhoRpp38 or PhoPop5, PhoRpp30, and PhoRpp21 showed a detectable RNase P activity, and five reconstituted particles (R-4Ps) composed of pRNA and four proteins exhibited RNase P activity, albeit at reduced level compared to that of the reconstituted particle (R-5P) composed of pRNA and five proteins. Time-course analysis of the RNase P activities of R-4Ps indicated that the R-4Ps lacking PhoPop5, PhoRpp21, or PhoRpp30 had virtually reduced activity, while omission of PhoRpp29 or PhoRpp38 had a slight effect on the activity. The results indicate that the proteins contribute to RNase P activity in order of PhoPop5 > PhoRpp30 > PhoRpp21 > PhoRpp29 > PhoRpp38. It was further found that R-4Ps showed a characteristic Mg2+ ion dependency approximately identical to that of R-5P. However, R-4Ps had optimum temperature of around at 55 degrees C which is lower than 70 degrees C for R-5P. Together, it is suggested that the P. horikoshii RNase P proteins are predominantly involved in optimization of the pRNA conformation, though they are individually dispensable for RNase P activity in vitro.

  9. A three-dimensional model of RNase P in the hyperthermophilic archaeon Pyrococcus horikoshii OT3.

    PubMed

    Gao, Xuzhu; Oshima, Kosuke; Ueda, Toshifumi; Nakashima, Takashi; Kimura, Makoto

    2017-09-19

    Ribonuclease P (RNase P) is an endoribonuclease involved in maturation of the 5'-end of tRNA. We found previously that RNase P in the hyperthermophilic archaeon Pyrococcus horikoshii OT3 consists of a catalytic RNase P RNA (PhopRNA) and five protein cofactors designated PhoPop5, PhoRpp21, PhoRpp29, PhoRpp30, and PhoRpp38. The crystal structures of the five proteins have been determined, a three-dimensional (3-D) model of PhopRNA has been constructed, and biochemical data, including protein-RNA interaction sites, have become available. Here, this information was combined to orient the crystallographic structures of the proteins relative to their RNA binding sites in the PhopRNA model. Some alterations were made to the PhopRNA model to improve the fit. In the resulting structure, a heterotetramer composed of PhoPop5 and PhoRpp30 bridges helices P3 and P16 in the PhopRNA C-domain, thereby probably stabilizing a double-stranded RNA structure (helix P4) containing catalytic Mg(2+) ions, while a heterodimer of PhoRpp21 and PhoRpp29 locates on a single-stranded loop connecting helices P11 and P12 in the specificity domain (S-domain) in PhopRNA, probably forming an appropriate conformation of the precursor tRNA (pre-tRNA) binding site. The fifth protein PhoRpp38 binds each kink-turn (K-turn) motif in helices P12.1, P12.2, and P16 in PhopRNA. Comparison of the structure of the resulting 3-D model with that of bacterial RNase P suggests transition from RNA-RNA interactions in bacterial RNase P to protein-RNA interactions in archaeal RNase P. The proposed 3-D model of P. horikoshii RNase P will serve as a framework for further structural and functional studies on archaeal, as well as eukaryotic, RNase Ps. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. OT2_eegami_6: SPIRE Snapshot Survey II: Using SPT/CODEX Massive Clusters as Powerful Gravitational Lenses

    NASA Astrophysics Data System (ADS)

    Egami, E.

    2011-09-01

    On the extragalactic side, one of the most remarkable results coming out of Herschel is the discovery of extremely bright (>100 mJy in the SPIRE bands) gravitationally lensed galaxies. The great sensitivity and mapping speed of SPIRE have enabled us to find these rare extraordinary objects. What is truly exciting about these bright lensed galaxies is that they enable a variety of detailed multi-wavelength follow-up observations, shedding new light on the physical properties of these high-redshift sources. In this regard, our OT1 program, "SPIRE Snapshot Survey of Massive Galaxy Clusters" turned out to be a great success. After imaging ~50 galaxies out of 279 in the program, we have already found two spectacularly bright lensed galaxies, one of which is at a redshift of 4.69. This type of cluster-lensed sources are not only bright but also spatially stretched over a large scale, so ALMA (or NOEMA in the north) is likely to be able to study them at the level of individual GMCs. Such studies will open up a new frontier in the study of high-redshift galaxies. Here, we propose to extend this highly efficient and effective survey of gravitationally lensed galaxies to another 353 clusters carefully chosen from the SPT and CODEX cluster samples. These samples contain newly discovered high-redshift (z>0.3) massive (>3-4e14 Msun) clusters, which can be used as powerful gravitational lenses to magnify sources at high redshift. With the OT1 and OT2 surveys together, we expect to find ~20 highly magnified SPIRE sources with exceptional brightnesses (assuming a discovery rate of ~1/30). Such a unique sample of extraordinary objects will enable a variety of follow-up sciences, and will therefore remain as a great legacy of the Herschel mission for years to come.

  11. Fermi and Swift observations of correlated outburst activity from the BL Lac object OT 081 (PKS 1749+096)

    NASA Astrophysics Data System (ADS)

    Ciprini, Stefano; Gonzalez, Josefa Becerra; Pivato, Giovanna; Thompson, David J.

    2016-07-01

    We report a strong multi-wavelength outburst in the BL Lac object OT 081 (also known as PKS 1749+096, 4C +09.57) with the radio counterpart position R.A.: 267.88674 deg, Dec.: 9.65020 deg (J2000.0, Lanyi et al. 2010, AJ, 139, 1695) and with redshift z=0.322 (Stickel, Fried, Kuehr 1988, A & A, 191, 16). Gamma ray and X-ray flares reached peaks during the interval 2016 July 16 and 20 simultaneous with an optical outburst (Balonek et al, 2016, ATel #9259).

  12. Catalytic activity of refolded penicillin acylase subunits in aqueous solution and aerosol ot reversed micelles in octane.

    PubMed

    Kabakov, V E; Klyachko, N L; Levashov, A V

    1994-08-01

    Refolded alpha and beta subunits of penicillin acylase were produced by gel-filtration under denaturing conditions followed by removal of urea through dialysis. Preparations of both renatured subunits hidrolysed specific substrate--phenylacetic acid p-nitroanilide in buffer and in the system of Aerosol OT reversed micelles, the alpha subunit being most catalytically active at Wo = 11.9, while the beta subunit--at Wo = 17.5. There was a good correlation between the position of the found maxima, the theoretically calculated optimal hydration degrees as well as the earlier reported profile of enzymatic activity for native enzyme in reversed micelles.

  13. The Kcnq1ot1 Long Non-Coding RNA Affects Chromatin Conformation and Expression of Kcnq1, but Does Not Regulate Its Imprinting in the Developing Heart

    PubMed Central

    Korostowski, Lisa; Sedlak, Natalie; Engel, Nora

    2012-01-01

    Although many of the questions raised by the discovery of imprinting have been answered, we have not yet accounted for tissue- or stage-specific imprinting. The Kcnq1 imprinted domain exhibits complex tissue-specific expression patterns co-existing with a domain-wide cis-acting control element. Transcription of the paternally expressed antisense non-coding RNA Kcnq1ot1 silences some neighboring genes in the embryo, while others are unaffected. Kcnq1 is imprinted in early cardiac development but becomes biallelic after midgestation. To explore this phenomenon and the role of Kcnq1ot1, we used allele-specific assays and chromosome conformational studies in wild-type mice and mice with a premature termination mutation for Kcnq1ot1. We show that Kcnq1 imprinting in early heart is established and maintained independently of Kcnq1ot1 expression, thus excluding a role for Kcnq1ot1 in repressing Kcnq1, even while silencing other genes in the domain. The exact timing of the mono- to biallelic transition is strain-dependent, with the CAST/EiJ allele becoming activated earlier and acquiring higher levels than the C57BL/6J allele. Unexpectedly, Kcnq1ot1 itself also switches to biallelic expression specifically in the heart, suggesting that tissue-specific loss of imprinting may be common during embryogenesis. The maternal Kcnq1ot1 transcript is shorter than the paternal ncRNA, and its activation depends on an alternative transcriptional start site that bypasses the maternally methylated promoter. Production of Kcnq1ot1 on the maternal chromosome does not silence Cdkn1c. We find that in later developmental stages, however, Kcnq1ot1 has a role in modulating Kcnq1 levels, since its absence leads to overexpression of Kcnq1, an event accompanied by an aberrant three-dimensional structure of the chromatin. Thus, our studies reveal regulatory mechanisms within the Kcnq1 imprinted domain that operate exclusively in the heart on Kcnq1, a gene crucial for heart development and function

  14. NGC 300 OT2008-1 as a Scaled-down Version of the Eta Carinae Great Eruption

    NASA Astrophysics Data System (ADS)

    Kashi, Amit; Frankowski, Adam; Soker, Noam

    2010-01-01

    We propose that the intermediate luminosity optical transient NGC 300 OT2008-1 was powered by a mass transfer episode from an extreme asymptotic giant branch star to a main sequence (MS) companion. We find a remarkable similarity in the shapes of the light curves of the several months long NGC 300 OT2008-1 outburst, of the three-month long 2002 enigmatic outburst of the B star V838 Mon, and the twenty-year long Great Eruption of the massive binary system Eta Carinae that occurred in the 19th century. Their similar decline properties hint to a common energy source: a gravitational energy that is released by accretion onto an MS star. These events populate a specific strip in the total energy versus outburst duration diagram. The strip is located between novae and supernovae. We add recent transient events to that diagram and find them to occupy the same strip. This suggests that some intermediate luminosity optical transients are powered by accretion onto a compact object (not necessarily an MS star). These transients are expected to produce bipolar ejecta as a result of the geometry of the accretion process.

  15. Purification, crystallization and initial X-ray crystallographic analysis of the putative GTPase PH0525 from Pyrococcus horikoshii OT3

    SciTech Connect

    Lokanath, Neratur K.; Yamamoto, Hitoshi; Matsunaga, Emiko; Sugahara, Mitsuaki; Kunishima, Naoki

    2005-10-01

    The putative GTPase PH0525 from P. horikoshii OT3 was crystallized using the microbatch method. Crystals were formed under two different conditions, providing two distinct crystal forms. Diffraction data from the two forms were measured to resolution limits of 2.30 and 2.40 Å and processed in space groups P2{sub 1} and C222{sub 1}, respectively. GTPases are involved in diverse cellular functions including cell proliferation, cytoskeleton organization and intracellular traffic. The putative GTPase PH0525 from Pyrococcus horikoshii OT3 has been overexpressed in Escherichia coli and purified. Two distinct crystal forms were grown by the microbatch method at 291 K using a very high protein concentration (80 mg ml{sup −1}). Native data sets extending to resolutions of 2.3 and 2.4 Å have been collected and processed in space groups P2{sub 1} and C222{sub 1}, respectively. Assuming the presence of one monomer per asymmetric unit gives V{sub M} values of 2.6 and 2.4 Å{sup 3} Da{sup −1} for the P2{sub 1} and C222{sub 1} forms, respectively, which is consistent with dynamic light-scattering experiments, which show a monomeric state of the protein in solution.

  16. Purification, crystallization and preliminary crystallographic analysis of RecA superfamily ATPase PH0284 from Pyrococcus horikoshii OT3

    SciTech Connect

    Bagautdinov, Bagautdin; Kunishima, Naoki

    2006-04-01

    RecA superfamily ATPase PH0284 from P. horikoshii OT3 was overexpressed, purified, crystallized and cocrystallized with ATP. Both crystal forms belong to the trigonal space group P3{sub 2}21 and diffract X-rays to 2.0 and 2.3 Å resolution, respectively. Circadian (daily) protein clocks are found in cyanobacteria, where a complex of the KaiA, KaiB and KaiC proteins generates circadian rhythms. The 28.09 kDa KaiC homologue PH0284 protein from Pyrococcus horikoshii OT3 was cloned and expressed and the purified protein was crystallized by the oil-microbatch method at 295 K. X-ray diffraction data from the crystal were collected to 2.0 Å resolution using synchrotron radiation at 100 K. The crystal belongs to the trigonal space group P3{sub 2}21, with unit-cell parameters a = b = 96.06, c = 298.90 Å. Assuming the presence of one hexamer in the asymmetric unit gives a V{sub M} value of 2.36 Å{sup 3} Da{sup −1} and a solvent content of 47.9%. A cocrystal with ATP was prepared and a diffraction data set was collected at 2.3 Å resolution.

  17. Mechanistic basis for high reactivity of (salen)Co-OTs in the hydrolytic kinetic resolution of terminal epoxides.

    PubMed

    Nielsen, Lars P C; Zuend, Stephan J; Ford, David D; Jacobsen, Eric N

    2012-03-02

    The (salen)Co(III)-catalyzed hydrolytic kinetic resolution (HKR) of terminal epoxides is a bimetallic process with a rate controlled by partitioning between a nucleophilic (salen)Co-OH catalyst and a Lewis acidic (salen)Co-X catalyst. The commonly used (salen)Co-OAc and (salen)Co-Cl precatalysts undergo complete and irreversible counterion addition to epoxide during the course of the epoxide hydrolysis reaction, resulting in quantitative formation of weakly Lewis acidic (salen)Co-OH and severely diminished reaction rates in the late stages of HKR reactions. In contrast, (salen)Co-OTs maintains high reactivity over the entire course of HKR reactions. We describe here an investigation of catalyst partitioning with different (salen)Co-X precatalysts and demonstrate that counterion addition to epoxide is reversible in the case of the (salen)Co-OTs. This reversible counterion addition results in stable partitioning between nucleophilic and Lewis acidic catalyst species, allowing highly efficient catalysis throughout the course of the HKR reaction.

  18. Mechanistic Basis for High Reactivity of (salen)Co–OTs in the Hydrolytic Kinetic Resolution of Terminal Epoxides

    PubMed Central

    Nielsen, Lars P. C.; Zuend, Stephan J.; Ford, David D.; Jacobsen, Eric N.

    2012-01-01

    The (salen)Co(III)-catalyzed hydrolytic kinetic resolution (HKR) of terminal epoxides is a bimetallic process with a rate controlled by partitioning between a nucleophilic (salen)Co–OH catalyst and a Lewis acidic (salen)Co–X catalyst. The commonly used (salen)Co–OAc and (salen)Co–Cl precatalysts undergo complete and irreversible counterion addition to epoxide during the course of the epoxide hydrolysis reaction, resulting in quantitative formation of weakly Lewis acidic (salen)Co–OH, and severely diminished reaction rates in the late stages of HKR reactions. In contrast, (salen)Co–OTs maintains high reactivity over the entire course of HKR reactions. We describe here an investigation of catalyst partitioning with different (salen)Co–X precatalysts, and demonstrate that counterion addition to epoxide is reversible in the case of the (salen)Co–OTs. This reversible counterion addition results in stable partitioning between nucleophilic and Lewis acidic catalyst species, allowing highly efficient catalysis throughout the course of the HKR reaction. PMID:22292515

  19. Overproduction and preliminary crystallographic study of a human kynurenine aminotransferase II homologue from Pyrococcus horikoshii OT3

    SciTech Connect

    Chon, Hyongi; Matsumura, Hiroyoshi; Shimizu, Shoko; Maeda, Nao; Koga, Yuichi; Takano, Kazufumi; Kanaya, Shigenori

    2005-03-01

    A human kynurenine aminotransferase II homologue from P. horikoshii OT3 has been overproduced in E. coli, purified, and characterized. Crystals of this protein have been obtained and analyzed by X-ray diffraction. The Pyrococcus horikoshii OT3 genome contains a gene encoding a human kynurenine aminotransferase II (KAT II) homologue, which consists of 428 amino-acid residues and shows an amino-acid sequence identity of 30% to human KAT II. This gene was overexpressed in Escherichia coli and the recombinant protein (Ph-KAT II) was purified. Gel-filtration chromatography showed that Ph-KAT II exists as a homodimer. Ph-KAT II exhibited enzymatic activity that catalyzes the transamination of l-kynurenine to produce kynurenic acid. Crystals of Ph-KAT II were grown using the sitting-drop vapour-diffusion method and native X-ray diffraction data were collected to 2.2 Å resolution using synchrotron radiation from station BL44XU at SPring-8. The crystals belong to the centred orthorhombic space group C222{sub 1}, with unit-cell parameters a = 71.75, b = 86.84, c = 137.30 Å. Assuming one molecule per asymmetric unit, the V{sub M} value was 2.19 Å{sup 3} Da{sup −1} and the solvent content was 43.3%.

  20. Anti-Tumor Effects after Adoptive Transfer of IL-12 Transposon-Modified Murine Splenocytes in the OT-I-Melanoma Mouse Model.

    PubMed

    Galvan, Daniel L; O'Neil, Richard T; Foster, Aaron E; Huye, Leslie; Bear, Adham; Rooney, Cliona M; Wilson, Matthew H

    2015-01-01

    Adoptive transfer of gene modified T cells provides possible immunotherapy for patients with cancers refractory to other treatments. We have previously used the non-viral piggyBac transposon system to gene modify human T cells for potential immunotherapy. However, these previous studies utilized adoptive transfer of modified human T cells to target cancer xenografts in highly immunodeficient (NOD-SCID) mice that do not recapitulate an intact immune system. Currently, only viral vectors have shown efficacy in permanently gene-modifying mouse T cells for immunotherapy applications. Therefore, we sought to determine if piggyBac could effectively gene modify mouse T cells to target cancer cells in a mouse cancer model. We first demonstrated that we could gene modify cells to express murine interleukin-12 (p35/p40 mIL-12), a transgene with proven efficacy in melanoma immunotherapy. The OT-I melanoma mouse model provides a well-established T cell mediated immune response to ovalbumin (OVA) positive B16 melanoma cells. B16/OVA melanoma cells were implanted in wild type C57Bl6 mice. Mouse splenocytes were isolated from C57Bl6 OT-I mice and were gene modified using piggyBac to express luciferase. Adoptive transfer of luciferase-modified OT-I splenocytes demonstrated homing to B16/OVA melanoma tumors in vivo. We next gene-modified OT-I cells to express mIL-12. Adoptive transfer of mIL-12-modified mouse OT-I splenocytes delayed B16/OVA melanoma tumor growth in vivo compared to control OT-I splenocytes and improved mouse survival. Our results demonstrate that the piggyBac transposon system can be used to gene modify splenocytes and mouse T cells for evaluating adoptive immunotherapy strategies in immunocompetent mouse tumor models that may more directly mimic immunotherapy applications in humans.

  1. Data Multiplexing Network (DMN), phase 3: Equipment Operational Test and Evaluation (OT&E)/Integration test plan

    NASA Astrophysics Data System (ADS)

    Bell, Wayne

    1991-10-01

    The presented plan addresses the Operational Test and Evaluation (OT&E)/Integration testing of the Data Multiplexing Network (DMN) equipment in the current NAS environment. The approach and concept is to conduct integration tests with appropriate National Airspace System (NAS) systems to verify that NAS requirements and DMN specifications and Statistical Multiplexer requirements were satisfied. This will be accomplished by conducting unit level tests at the Federal Aviation Administration (FAA) Technical Center and extensive integration tests at the key test sites of Albuquerque, New Mexico; Denver, Colorado; and Minneapolis, Minnesota Air Route Traffic Control Centers (ARTCC). The DMN equipment being procured includes Deterministic Time Division Multiplexing (DTDM) Commercial Off-The-Shelf (COTS) equipment and the NON-COTS equipment (a/b switch and clock box). This plan describes the test program for the DTDM COTS equipment.

  2. [Hydrophobic formate dehydrogenase from Pseudomonas sp. 101 in the system of reverse micelles of aerosol OT in octane].

    PubMed

    Trofimova, D N; Levashov, A V

    2002-01-01

    NAD(+)-dependent formate dehydrogenase (FDH) was hydrophobized with palmitoyl chloride to give the samples with various modification degrees (2-10). The native and modified FDHs were comparatively studied in the system of reverse micelles of Aerosol OT in octane. Like the native, the modified enzyme displayed three maxima in the curve of dependence of its catalytic activity on the degree of surfactant hydration (the micelle size), which reflect the enzyme functioning in the form of a monomer, dimer, or octamer. The peak corresponding to the functioning of the FDH dimer was found to decrease along with an increase in the modification degree. Thus, the modified enzyme mainly functions in the form of monomer and octamer. The modified FDH displayed membranotropy and revealed the dependence of catalytic activity on surfactant concentration.

  3. Synthesis and Characterization of MO[OSi(OtBu)3]4 andMO2[OSi(OtBu)3]2 (M=Mo,W): Models for Isolated Oxo-Molybdenum and-Tungsten Sites on Silica and Precursors to Molybdena- and Tungsta-SilicaMaterials

    SciTech Connect

    Jarupatrakorn, Jonggol; Coles, Martyn P.; Tilley, T. Don

    2005-01-20

    The tri(alkoxy)siloxy complexes MO[OSi(OtBu)3]4 (1, M = Mo and 2, M = W) were prepared from MOCl4 and LiOSi(OtBu)3. Similarly, reactions of MO2Cl2(DME) with LiOSi(OtBu)3 afforded the new siloxide complexes MO2[OSi(OtBu)3]2 (3, M = Mo and 4, M = W), which are thermally unstable at ambient temperature. More stable compounds were obtained by the crystallizations of 3 and 4 in a coordinating solvent, to form the ether adducts MoO2[OSi(OtBu)3]2(THF) (3a) and WO2[OSi(OtBu)3]2(DME) (4a). These compounds serve as soluble models for isolated molybdenum or tungsten atoms on a silica surface and were characterized by 1H, 13C, 29Si, 95Mo, and 183W NMR, FT-Raman, FT-IR, and UV-vis spectroscopies. Compounds 1, 2, 3a, and 4a were used to prepare metal-oxide silica composites via the thermolytic molecular precursor method. The xerogels obtained from the thermolyses of 1, 2, 3a, and 4a in toluene contained mesoporosity with surface areas of 10, 230, 106, and 270 m2 g-1, respectively. Despite the high surface areas for most samples, these xerogels contain MO3 domains. Complexes 1 and 2 were also used to introduce molybdenum and tungsten sites, respectively, onto mesoporous SBA-15 silica via displacement of the -OSi(OtBu)3 ligand for a siloxyl group from the silica surface. All molybdenum- and tungsten-containing systems were tested as catalysts for the epoxidation of cyclohexene using tert-butyl hydroperoxide (TBHP) or aqueous H2O2 as the oxidant.

  4. Self-assembly of new surface active ionic liquids based on Aerosol-OT in aqueous media.

    PubMed

    Rao, K Srinivasa; Gehlot, Praveen Singh; Trivedi, Tushar J; Kumar, Arvind

    2014-08-15

    New anionic ionic liquid surfactants have been synthesized by replacing the sodium cation of Aerosol-OT (sodium dioctylsulfosuccinate, [Na]AOT) with various biocompatible moieties, such as 1-butyl-3-methyl imidazolium ([C4mim]), proliniumisopropylester ([ProC3]), cholinium ([Cho]), and guanidinium ([Gua]). The Aerosol-OT derived ionic liquids (AOT-ILs) were found fairly soluble in water and formed vesicles above a critical vesicle concentration (CVC) which depended upon the nature of cation, and followed the order: [ProC3]<[C4mim]<[Gua]<[Cho]

  5. A Genome-wide Association Study of Bipolar Disorder with Comorbid Eating Disorder Replicates the SOX2-OT Region

    PubMed Central

    Liu, Xiaohua; Kelsoe, John R.; Greenwood, Tiffany A.

    2015-01-01

    Background Bipolar disorder is a heterogeneous mood disorder associated with several important clinical comorbidities, such as eating disorders. This clinical heterogeneity complicates the identification of genetic variants contributing to bipolar susceptibility. Here we investigate comorbidity of eating disorders as a subphenotype of bipolar disorder to identify genetic variation that is common and unique to both disorders. Methods We performed a genome-wide association analysis contrasting 184 bipolar subjects with eating disorder comorbidity against both 1,370 controls and 2,006 subjects with bipolar disorder only from the Bipolar Genome Study (BiGS). Results The most significant genome-wide finding was observed bipolar with comorbid eating disorder vs. controls within SOX2-OT (p=8.9×10−8 for rs4854912) with a secondary peak in the adjacent FXR1 gene (p=1.2×10−6 for rs1805576) on chromosome 3q26.33. This region was also the most prominent finding in the case-only analysis (p=3.5×10−7 and 4.3×10−6, respectively). Several regions of interest containing genes involved in neurodevelopment and neuroprotection processes were also identified. Limitations While our primary finding did not quite reach genome-wide significance, likely due to the relatively limited sample size, these results can be viewed as a replication of a recent study of eating disorders in a large cohort. Conclusions These findings replicate the prior association of SOX2-OT with eating disorders and broadly support the involvement of neurodevelopmental/neuroprotective mechanisms in the pathophysiology of both disorders. They further suggest that different clinical manifestations of bipolar disorder may reflect differential genetic contributions and argue for the utility of clinical subphenotypes in identifying additional molecular pathways leading to illness. PMID:26433762

  6. DUSTY EXPLOSIONS FROM DUSTY PROGENITORS: THE PHYSICS OF SN 2008S AND THE 2008 NGC 300-OT

    SciTech Connect

    Kochanek, C. S.

    2011-11-01

    SN 2008S and the 2008 NGC 300-OT were explosive transients of stars self-obscured by very dense, dusty stellar winds. An explosive transient with an unobserved shock breakout luminosity of order 10{sup 10} L{sub sun} is required to render the transients little obscured and visible in the optical at their peaks. Such a large breakout luminosity then implies that the progenitor stars were cool, red supergiants, most probably {approx}9 M{sub sun} extreme asymptotic giant branch stars. As the shocks generated by the explosions propagate outward through the dense wind, they produce a shock luminosity in soft X-rays that powers the long-lived luminosity of the transients. Unlike typical cases of transients exploding into a surrounding circumstellar medium, the progenitor winds in these systems are optically thick to soft X-rays, easily absorb radio emission, and rapidly reform dust destroyed by the peak luminosity of the transients. As a result, X-rays are absorbed by the gas and the energy is ultimately radiated by the reformed dust. Three years post-peak, both systems are still significantly more luminous than their progenitor stars, but they are again fully shrouded by the reformed dust and only visible in the mid-IR. The high luminosity and heavy obscuration may make it difficult to determine the survival of the progenitor stars for {approx}10 years. However, our model indicates that SN 2008S, but not the NGC 300-OT, should now be a detectable X-ray source. SN 2008S has a higher estimated shock velocity and a lower density wind, so the X-rays begin to escape at a much earlier phase.

  7. Cubic Siloxanes with Both Si-H and Si-OtBu Groups for Site-Selective Siloxane Bond Formation.

    PubMed

    Saito, Shohei; Yamasue, Nao; Wada, Hiroaki; Shimojima, Atsushi; Kuroda, Kazuyuki

    2016-09-19

    Cage-type siloxanes have attracted increasing attention as building blocks for silica-based nanomaterials as their corners can be modified with various functional groups. Cubic octasiloxanes incorporating both Si-H and Si-OtBu groups [(tBuO)n H8-n Si8 O12 ; n=1, 2 or 7] have been synthesized by the reaction of octa(hydridosilsesquioxane) (H8 Si8 O12 ) and tert-butyl alcohol in the presence of a Et2 NOH catalyst. The Si-H and Si-OtBu groups are useful for site-selective formation of Si-O-Si linkages without cage structure deterioration. The Si-H group can be selectively hydrolyzed to form a Si-OH group in the presence of Et2 NOH, enabling the formation of the monosilanol compound (tBuO)7 (HO)Si8 O12 . The Si-OH group can be used for either intermolecular condensation to form a dimeric cage compound or silylation to introduce new reaction sites. Additionally, the alkoxy groups of (tBuO)7 HSi8 O12 can be treated with organochlorosilanes in the presence of a BiCl3 catalyst to form Si-O-Si linkages, while the Si-H group remains intact. These results indicate that such bifunctional cage siloxanes allow for stepwise Si-O-Si bond formation to design new siloxane-based nanomaterials. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. A genome-wide association study of bipolar disorder with comorbid eating disorder replicates the SOX2-OT region.

    PubMed

    Liu, Xiaohua; Kelsoe, John R; Greenwood, Tiffany A

    2016-01-01

    Bipolar disorder is a heterogeneous mood disorder associated with several important clinical comorbidities, such as eating disorders. This clinical heterogeneity complicates the identification of genetic variants contributing to bipolar susceptibility. Here we investigate comorbidity of eating disorders as a subphenotype of bipolar disorder to identify genetic variation that is common and unique to both disorders. We performed a genome-wide association analysis contrasting 184 bipolar subjects with eating disorder comorbidity against both 1370 controls and 2006 subjects with bipolar disorder only from the Bipolar Genome Study (BiGS). The most significant genome-wide finding was observed bipolar with comorbid eating disorder vs. controls within SOX2-OT (p=8.9×10(-8) for rs4854912) with a secondary peak in the adjacent FXR1 gene (p=1.2×10(-6) for rs1805576) on chromosome 3q26.33. This region was also the most prominent finding in the case-only analysis (p=3.5×10(-7) and 4.3×10(-6), respectively). Several regions of interest containing genes involved in neurodevelopment and neuroprotection processes were also identified. While our primary finding did not quite reach genome-wide significance, likely due to the relatively limited sample size, these results can be viewed as a replication of a recent study of eating disorders in a large cohort. These findings replicate the prior association of SOX2-OT with eating disorders and broadly support the involvement of neurodevelopmental/neuroprotective mechanisms in the pathophysiology of both disorders. They further suggest that different clinical manifestations of bipolar disorder may reflect differential genetic contributions and argue for the utility of clinical subphenotypes in identifying additional molecular pathways leading to illness. Copyright © 2015 Elsevier B.V. All rights reserved.

  9. Glucuronidation of OTS167 in Humans Is Catalyzed by UDP-Glucuronosyltransferases UGT1A1, UGT1A3, UGT1A8, and UGT1A10

    PubMed Central

    Ramírez, Jacqueline; Mirkov, Snezana; House, Larry K.

    2015-01-01

    OTS167 is a potent maternal embryonic leucine zipper kinase inhibitor undergoing clinical testing as antineoplastic agent. We aimed to identify the UDP-glucuronosyltransferases (UGTs) involved in OTS167 metabolism, study the relationship between UGT genetic polymorphisms and hepatic OTS167 glucuronidation, and investigate the inhibitory potential of OTS167 on UGTs. Formation of a single OTS167-glucuronide (OTS167-G) was observed in pooled human liver (HLM) (Km = 3.4 ± 0.2 µM), intestinal microsomes (HIM) (Km = 1.7 ± 0.1 µM), and UGTs. UGT1A1 (64 µl/min/mg) and UGT1A8 (72 µl/min/mg) exhibited the highest intrinsic clearances (CLint) for OTS167, followed by UGT1A3 (51 µl/min/mg) and UGT1A10 (47 µl/min/mg); UGT1A9 was a minor contributor. OTS167 glucuronidation in HLM was highly correlated with thyroxine glucuronidation (r = 0.91, P < 0.0001), SN-38 glucuronidation (r = 0.79, P < 0.0001), and UGT1A1 mRNA (r = 0.72, P < 0.0001). Nilotinib (UGT1A1 inhibitor) and emodin (UGT1A8 and UGT1A10 inhibitor) exhibited the highest inhibitory effects on OTS167-G formation in HLM (68%) and HIM (47%). We hypothesize that OTS167-G is an N-glucuronide according to mass spectrometry. A significant association was found between rs6706232 and reduced OTS167-G formation (P = 0.03). No or weak UGT inhibition (range: 0–21%) was observed using clinically relevant OTS167 concentrations (0.4–2 µM). We conclude that UGT1A1 and UGT1A3 are the main UGTs responsible for hepatic formation of OTS167-G. Intestinal UGT1A1, UGT1A8, and UGT1A10 may contribute to first-pass OTS167 metabolism after oral administration. PMID:25870101

  10. Spectral classification of nuclear transient MASTER OT J122100.9-533150.1/Gaia17bhd (AT2017edu) as SN Ia.

    NASA Astrophysics Data System (ADS)

    Gromadzki, M.; Hamanowicz, A.; Wyrzykowski, L.

    2017-05-01

    We report the spectroscopic classification of a nuclear transient Gaia17bhd (AT2017edu), also known as MASTER OT J122100.9-533150.1, discovered by MASTER-OAFA auto-detection system ( Balanutsa et al, ATel #10291) and Gaia Science Alerts system (http://gsaweb.ast.cam.ac.uk/alerts/alert/Gaia17bhd).

  11. Photogenerated charge carrier recombination processes in CdS/P3OT solar cells: effect of structural and optoelectronic properties of CdS films

    NASA Astrophysics Data System (ADS)

    Cortina, H.; Pineda, E.; Campos, J.; Nicho, M. E.; Hu, H.

    2011-09-01

    Research and development activities in organic solar cells have been intensified in the last two decades, and the reported energy conversion efficiency in small cell samples is rapidly increased. However, the relation between cell performance and material preparation conditions is not fully understood. In this work charge carrier recombination processes in hybrid poly-3-octylthiophene (P3OT)/cadmium sulfide (CdS) photovoltaic cells were analyzed as a function of structural and optoelectronic properties of chemical bath deposited CdS thin films. The temperature of the bath solution varied between 60 and 80 °C, and the deposition time from 1 to 3 h. Charge carrier recombination times in CdS films were measured with photoconductance decay technique, whereas the same time in P3OT films was estimated by Time-of-Flight method. Charge carrier recombination rates at CdS/P3OT interface were determined by transient photovoltage technique. It is found that CdS films grown at lower solution temperature (60 °C) give a higher charge carrier recombination rate at CdS/P3OT interface and larger short-circuit current density and energy conversion efficiency values in the corresponding solar cells, in comparison with the 80 °C deposited ones. This improvement could come from the reduction of charge carrier trap density inside grains as well as at grain boundaries in lower temperature deposited CdS films.

  12. /sup 45/Ca efflux for myometrial cells: comparison of the effects of prostaglandin F/sub 2/. cap alpha. (PGF/sub 2/), oxytocin (OT) and arachidonate (A)

    SciTech Connect

    Katona, G.; Molnar, M.; Toth, M.; Hertelendy, F.

    1986-03-01

    The aim of this study was to measure PGF/sub 2..cap alpha../-induced Ca/sup 2 +/ release from uterine cells and to compare this to the actions of OT and A. Smooth muscle cells isolated from the uterus (shell gland) of laying hens were cultured for 7 days in M199 plus 10% fetal calf serum. The cells were treated with digitonin (20..mu..M) and preloaded with /sup 45/Ca for 40 min. Addition of PGF/sub 2..cap alpha../ caused a biphasic /sup 45/Ca-efflux. There was a small but significant /sup 45/Ca-release within 30 sec (rapid phase) followed by a larger one within 7 min (slow phase). In comparison, both OT and A stimulated /sup 45/Ca efflux during a single, slow phase. The maximal effect of A was observed at < 7 min, whereas that of OT was slower, peaking after 7 min. Mepacrin, an inhibitor of A release, attenuated the action of OT without having any effect on A promoted /sup 45/Ca-efflux. Indomethacin, an inhibitor of PG synthase, failed to suppress the Ca-releasing effect of A suggesting the A itself or a lipoxygenase product may have been responsible for the observed effects. Moreover, these results provide suggestive evidence that A release is an important step in the action of various uterotonic agents converging on the mobilization of intracellular Ca.

  13. Progesterone metabolism in bovine endometrial cells and the effect of metabolites on the responsiveness of the cells to OT-stimulation of PGF2alpha.

    PubMed

    Jamshidi, Ahmad A; Girard, Dominique; Beaudry, Francis; Goff, Alan K

    2007-11-01

    Oxytocin receptor (OTR) expression is suppressed by progesterone (P4) during the luteal phase of the estrous cycle and then it increases at the time of luteolysis, but its regulation is still not completely understood. The objective of this work was to characterize P4 metabolism by endometrial cells in vitro and determine if metabolites were able to modify prostaglandin secretion in response to oxytocin (OT). Endometrial epithelial and stromal cells were incubated with 3H-P4 or 3H-pregnenolone (P5) for 6 or 24 h. Metabolites in the medium were separated by HPLC. The results showed that P4 and P5 were converted to two major polar metabolites and a less polar metabolite that was identified as 5alpha- or 5beta-pregnanedione by LC/MS. Progesterone metabolism was similar in both stromal and epithelial cells. To determine if 5alpha- or 5beta-pregnanedione were able to modify PGF(2)alpha synthesis, cells were cultured with P4, 5alpha- or 5beta-pregnanedione (100 ng ml(-1)) for 48 h and then each group of cells was incubated for a further 4-6 h with or without OT (200 ng ml(-1)). Results showed that only P4 caused significant (P<0.001) increase in basal, but not OT-stimulated, PGF(2)alpha synthesis. OT binding assays showed no significant effect of progesterone or its metabolites on OTR concentration. In conclusion, bovine endometrial cells are able to metabolize pregnenolone and progesterone but neither 5alpha- nor 5beta-pregnanedione altered prostaglandin synthesis or OTR number in endometrial epithelial cells. These data suggest that 5-pregnanediones do not play a role in the regulation OT-stimulated PGF(2)alpha secretion during the bovine estrous cycle.

  14. The influence of polychlorinated biphenyls (PCBs), dichlorodiphenyltrichloroethane (DDT) and its metabolite-dichlorodiphenyldichloroethylene (DDE) on mRNA expression for NP-I/OT and PGA, involved in oxytocin synthesis in bovine granulosa and luteal cells.

    PubMed

    Mlynarczuk, Jaroslaw; Wrobel, Michal H; Kotwica, Jan

    2009-11-01

    The effect of polychlorinated biphenyls (PCBs) congeners (PCB 77, PCB 126, PCB 153) and their technical mixture-Aroclor (Ar) 1248, as well as dichlorodiphenyltrichloroethane (DDT) and its metabolite-dichlorodiphenyldichloroethylene (DDE; two individual isomers p,p'- and o,p'- or their mixture, 95% and 5%, respectively) at the dose of 10 ng/ml each, on the gene expression of (a) oxytocin (OT) precursor-neurophysin-oxytocin (NP-I/OT) and (b) peptidyl glycine-alpha-amidating mono-oxygenase (PGA), the terminal enzyme in the pathway of OT synthesis, was studied. Granulosa cells from follicles >1cm in diameter, collected on days 19-21 of estrous cycle, and luteal cells from corpora lutea (CL) collected on days 8-12 of the estrous cycle were used. The cells were incubated (6h) with these xenobiotics and the expression of NP-I/OT and PGA genes was determined. All PCBs increased (P<0.05) NP-I/OT gene expression in granulosa cells. Similarly, all PCBs but PCB 126 increased (P<0.05) PGA gene expression in these cells. DDT and DDE increased (P<0.05) gene expression of NP-I/OT in granulosa cells, while gene expression of PGA in these cells was stimulated (P<0.05) by DDE only. The mRNA expression for NP-I/OT and PGA in luteal cells was increased (P<0.05) by PCB 77 and PCB 153. Both DDE isomers and mixture also stimulated (P<0.05) of NP-I/OT mRNA expression, while increase (P<0.05) of PGA mRNA expression was elicited by incubation of these cells with DDE mixture and Ar 1248. Obtained data suggest that PCBs, DDT and DDE can affect the mRNA expression for NP-I/OT and PGA in bovine granulosa and luteal cells.

  15. Characterization of the PH1704 protease from Pyrococcus horikoshii OT3 and the critical functions of Tyr120.

    PubMed

    Zhan, Dongling; Bai, Aixi; Yu, Lei; Han, Weiwei; Feng, Yan

    2014-01-01

    The PH1704 protease from hyperthermophilic archaean Pyrococcus horikoshii OT3 is a member of DJ-1/ThiJ/PfpI superfamily with diverse functional subclasses. The recombinant PH1704 was efficiently purified and was systematically characterized by a combination of substrate specificity analysis, steady-state kinetics study and molecular docking research. The homogeneous protease was obtained as a presumed dodecamer with molecular weight of ∼240 kDa. Iodoacetamide strongly inhibited the peptidase activity, confirming that Cys100 is a nucleophilic residue. The recombinant protein was identified as both an aminopeptidase and an endopeptidase. Experimental data showed that L-R-amc was the best substrate of PH1704. Structural interaction fingerprint analysis (SIFt) indicated the binding pose of PH1704 and showed that Tyr120 is important in substrate binding. Kinetic parameters Kcat and Kcat/Km of the Y120P mutant with L-R-amc was about 7 and 7.8 times higher than that of the wild type (WT). For the endopeptidase Y120P with AAFR-amc, Kcat and Kcat/Km is 10- and 21-fold higher than that of WT. Experimental data indicate the important functions of Tyr120: involvement in enzyme activity to form a hydrogen bond with Cys100 and as an entrance gate of the substrate with Lys43. The results of this study can be used to investigate the DJ-1/ThiJ/PfpI superfamily.

  16. Purification, crystallization and preliminary crystallographic analysis of archaeal 6-pyruvoyl tetrahydrobiopterin synthase homologue PH0634 from Pyrococcus horikoshii OT3.

    PubMed

    Bagautdinov, Bagautdin; Sugahara, Mitsuaki; Kunishima, Naoki

    2007-01-01

    6-Pyruvoyl tetrahydrobiopterin synthase (PTPS) catalyses the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin, the second of the three enzymatic steps in the synthesis of tetrahydrobiopterin from GTP. PH0634, a 13.51 kDa archaeal PTPS homologue from Pyrococcus horikoshii OT3, was overexpressed as native and selenomethionine-substituted protein and the purified protein was crystallized by the oil-microbatch method at 295 K. X-ray diffraction data were collected to 2.1 A resolution from the native crystal using synchrotron radiation at 100 K. The crystal belongs to the orthorhombic space group P2(1)2(1)2(1), with unit-cell parameters a = 35.83, b = 95.71, c = 105.65 A. Threefold noncrystallographic symmetry was identified from self-rotation calculations. Assuming the presence of a trimer in the asymmetric unit, the solvent content is 45% (V(M) = 2.24 A3 Da(-1)). The selenomethionine-substituted crystal is isomorphous to the native crystal and diffracts X-rays to 2.9 A.

  17. Purification, crystallization and preliminary crystallographic analysis of archaeal 6-pyruvoyl tetrahydrobiopterin synthase homologue PH0634 from Pyrococcus horikoshii OT3

    PubMed Central

    Bagautdinov, Bagautdin; Sugahara, Mitsuaki; Kunishima, Naoki

    2007-01-01

    6-Pyruvoyl tetrahydrobiopterin synthase (PTPS) catalyses the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin, the second of the three enzymatic steps in the synthesis of tetrahydrobiopterin from GTP. PH0634, a 13.51 kDa archaeal PTPS homologue from Pyrococcus horikoshii OT3, was overexpressed as native and selenomethionine-substituted protein and the purified protein was crystallized by the oil-microbatch method at 295 K. X-ray diffraction data were collected to 2.1 Å resolution from the native crystal using synchrotron radiation at 100 K. The crystal belongs to the orthorhombic space group P212121, with unit-cell parameters a = 35.83, b = 95.71, c = 105.65 Å. Threefold noncrystallographic symmetry was identified from self-rotation calculations. Assuming the presence of a trimer in the asymmetric unit, the solvent content is 45% (V M = 2.24 Å3 Da−1). The selenomethionine-substituted crystal is isomorphous to the native crystal and diffracts X-rays to 2.9 Å. PMID:17183164

  18. Purification, crystallization and preliminary crystallographic analysis of RecA superfamily ATPase PH0284 from Pyrococcus horikoshii OT3

    PubMed Central

    Bagautdinov, Bagautdin; Kunishima, Naoki

    2006-01-01

    Circadian (daily) protein clocks are found in cyanobacteria, where a complex of the KaiA, KaiB and KaiC proteins generates circadian rhythms. The 28.09 kDa KaiC homologue PH0284 protein from Pyrococcus horikoshii OT3 was cloned and expressed and the purified protein was crystallized by the oil-microbatch method at 295 K. X-ray diffraction data from the crystal were collected to 2.0 Å resolution using synchrotron radiation at 100 K. The crystal belongs to the trigonal space group P3221, with unit-cell parameters a = b = 96.06, c = 298.90 Å. Assuming the presence of one hexamer in the asymmetric unit gives a V M value of 2.36 Å3 Da−1 and a solvent content of 47.9%. A cocrystal with ATP was prepared and a diffraction data set was collected at 2.3 Å resolution. PMID:16582499

  19. Purification, crystallization and preliminary crystallographic analysis of the biotin–protein ligase from Pyrococcus horikoshii OT3

    PubMed Central

    Bagautdinov, Bagautdin; Kuroishi, Chizu; Sugahara, Mitsuaki; Kunishima, Naoki

    2005-01-01

    Biotin–protein ligase is an enzyme that catalyzes the ATP-dependent biotinylation of a specific lysine residue in acetyl-CoA carboxylase. The biotin–protein ligase from Pyrococcus horikoshii OT3 has been cloned, overexpressed and purified. Crystallization was performed by the microbatch method or the vapour-diffusion method using PEG 2000 as a precipitant at 295 K. X-ray diffraction data have been collected to 1.6 Å resolution from a native crystal and to 1.55 Å resolution from a selenomethionine-derivative crystal for multiple anomalous dispersion phasing using synchrotron radiation at 100 K. The native crystal belongs to the monoclinic space group P21, with unit-cell parameters a = 38.601, b = 78.264, c  =  70.147 Å, β = 101.48°. Assuming a homodimer per asymmetric unit gives a V M value of 2.14 Å3 Da−1 and a solvent content of 42.5%. Cocrystals with biotin, ADP and biotinyl-5′-AMP were prepared and diffraction data sets were collected to 1.6, 1.6 and 1.45 Å resolution, respectively. PMID:16510991

  20. Purification, crystallization and preliminary crystallographic analysis of the biotin-protein ligase from Pyrococcus horikoshii OT3.

    PubMed

    Bagautdinov, Bagautdin; Kuroishi, Chizu; Sugahara, Mitsuaki; Kunishima, Naoki

    2005-02-01

    Biotin-protein ligase is an enzyme that catalyzes the ATP-dependent biotinylation of a specific lysine residue in acetyl-CoA carboxylase. The biotin-protein ligase from Pyrococcus horikoshii OT3 has been cloned, overexpressed and purified. Crystallization was performed by the microbatch method or the vapour-diffusion method using PEG 2000 as a precipitant at 295 K. X-ray diffraction data have been collected to 1.6 A resolution from a native crystal and to 1.55 A resolution from a selenomethionine-derivative crystal for multiple anomalous dispersion phasing using synchrotron radiation at 100 K. The native crystal belongs to the monoclinic space group P2(1), with unit-cell parameters a = 38.601, b = 78.264, c = 70.147 A, beta = 101.48 degrees. Assuming a homodimer per asymmetric unit gives a VM value of 2.14 A3 Da(-1) and a solvent content of 42.5%. Cocrystals with biotin, ADP and biotinyl-5'-AMP were prepared and diffraction data sets were collected to 1.6, 1.6 and 1.45 A resolution, respectively.

  1. Purification, crystallization and preliminary crystallographic analysis of RecA superfamily ATPase PH0284 from Pyrococcus horikoshii OT3.

    PubMed

    Bagautdinov, Bagautdin; Kunishima, Naoki

    2006-04-01

    Circadian (daily) protein clocks are found in cyanobacteria, where a complex of the KaiA, KaiB and KaiC proteins generates circadian rhythms. The 28.09 kDa KaiC homologue PH0284 protein from Pyrococcus horikoshii OT3 was cloned and expressed and the purified protein was crystallized by the oil-microbatch method at 295 K. X-ray diffraction data from the crystal were collected to 2.0 angstroms resolution using synchrotron radiation at 100 K. The crystal belongs to the trigonal space group P3(2)21, with unit-cell parameters a = b = 96.06, c = 298.90 angstroms. Assuming the presence of one hexamer in the asymmetric unit gives a V(M) value of 2.36 angstroms3 Da(-1) and a solvent content of 47.9%. A cocrystal with ATP was prepared and a diffraction data set was collected at 2.3 angstroms resolution.

  2. Strong fluorescence emissions by H-aggregates of the dye thiacyanine in the presence of the surfactant aerosol-OT

    NASA Astrophysics Data System (ADS)

    Mandal, Anil Kumar; Pal, Medini Kanta

    2000-02-01

    The cationic dye 3,3 '-diethylthiacyanine iodide (THIA) in dilute aqueous solution shows weak fluorescence with a broad peak around 470 nm, and the anionic surfactant bis(2-ethylhexyl) sodium sulphosuccinate, called aerosol-OT (AOT) enhances the fluorescence of the dye. When excited at 422 nm ( λmax of THIA), the fluorescence peak of THIA, in the presence of increasing AOT concentrations up to its critical micellar concentration (CMC), is gradually reduced to a shoulder around 475 nm, and two additional sharp peaks at 494 and 601 nm are progressively developed. Above the CMC of AOT, the original 470 nm peak starts reappearing with simultaneous disappearance of the 494 and 601 nm peaks. At appropriate AOT concentrations (below CMC), THIA forms two metachromatic species (H-aggregates) showing strong absorption peaks at 377 and 366 nm. When excited at these metachromatic peaks, the fluorescence of the THIA/AOT system is, instead of being quenched, largely enhanced about 8-10 times compared to when excited at 422 nm, and above the CMC, fluorescence diminishes. Application of the principal component analysis method to the observed fluorescence spectra results in three pure component spectra with peaks at 470, 494 and 601 nm, which have been assigned to monomer, normal H-aggregates and twisted H-aggregates emission peaks, respectively. The twisted H-aggregates originate from the excited preexisting hexamer as well as from the excimer formed between excited and ground state trimers.

  3. OT J002656.6+284933 (CSS101212:002657+284933): an SU UMa-type dwarf nova with the longest superhump period

    NASA Astrophysics Data System (ADS)

    Kato, Taichi; Tordai, Tamás; Littlefield, Colin; Kasai, Kiyoshi; Shugarov, Sergey Yu.; Katysheva, Natalia; Zaostrojnykh, Anna M.; Pickard, Roger D.; de Miguel, Enrique; Antonyuk, Kirill; Antonyuk, Oksana; Pavlenko, Elena P.; Pit, Nikolai; Itoh, Hiroshi; Ruiz, Javier; Isogai, Keisuke; Kimura, Mariko; Wakamatsu, Yasuyuki; Vanmunster, Tonny; Stone, Geoff

    2017-06-01

    We observed the 2016 outburst of OT J002656.6+284933 (CSS101212:002657+284933) and found that it has the longest recorded [0.13225(1) d on average] superhumps among SU UMa-type dwarf novae. The object is the third known SU UMa-type dwarf nova above the period gap. The outburst, however, was unlike ordinary long-period SU UMa-type dwarf novae in that it showed two post-outburst rebrightenings. It showed superhump evolution similar to short-period SU UMa-type dwarf novae. We could constrain the mass ratio to less than 0.15 (most likely between 0.10 and 0.15) by using superhump periods in the early and post-superoutburst stages. These results suggest the possibility that OT J002656.6+284933 has an anomalously undermassive secondary and it should have followed a different evolutionary track from the standard one.

  4. Genome Sequence of Ostreococcus tauri Virus OtV-2 Throws Light on the Role of Picoeukaryote Niche Separation in the Ocean▿

    PubMed Central

    Weynberg, Karen D.; Allen, Michael J.; Gilg, Ilana C.; Scanlan, David J.; Wilson, William H.

    2011-01-01

    Ostreococcus tauri, a unicellular marine green alga, is the smallest known free-living eukaryote and is ubiquitous in the surface oceans. The ecological success of this organism has been attributed to distinct low- and high-light-adapted ecotypes existing in different niches at a range of depths in the ocean. Viruses have already been characterized that infect the high-light-adapted strains. Ostreococcus tauri virus (OtV) isolate OtV-2 is a large double-stranded DNA algal virus that infects a low-light-adapted strain of O. tauri and was assigned to the algal virus family Phycodnaviridae, genus Prasinovirus. Our working hypothesis for this study was that different viruses infecting high- versus low-light-adapted O. tauri strains would provide clues to propagation strategies that would give them selective advantages within their particular light niche. Sequence analysis of the 184,409-bp linear OtV-2 genome revealed a range of core functional genes exclusive to this low-light genotype and included a variety of unexpected genes, such as those encoding an RNA polymerase sigma factor, at least four DNA methyltransferases, a cytochrome b5, and a high-affinity phosphate transporter. It is clear that OtV-2 has acquired a range of potentially functional genes from its host, other eukaryotes, and even bacteria over evolutionary time. Such piecemeal accretion of genes is a trademark of large double-stranded DNA viruses that has allowed them to adapt their propagation strategies to keep up with host niche separation in the sunlit layers of the oceanic environment. PMID:21289127

  5. The chromate-inducible chrBACF operon from the transposable element TnOtChr confers resistance to chromium(VI) and superoxide.

    PubMed

    Branco, Rita; Chung, Ana Paula; Johnston, Tatiana; Gurel, Volkan; Morais, Paula; Zhitkovich, Anatoly

    2008-11-01

    Large-scale industrial use of chromium(VI) has resulted in widespread contamination with carcinogenic chromium(VI). The abilities of microorganisms to survive in these environments and to detoxify chromate require the presence of specific resistance systems. Here we report identification of the transposon-located (TnOtChr) chromate resistance genes from the highly tolerant strain Ochrobactrum tritici 5bvl1 surviving chromate concentrations of >50 mM. The 7,189-bp-long TnOtChr of the mixed Tn21/Tn3 transposon subfamily contains a group of chrB, chrA, chrC, and chrF genes situated between divergently transcribed resolvase and transposase genes. The chrB and chrA genes, but not chrF or chrC, were essential for establishment of high resistance in chromium-sensitive O. tritici. The chr promoter was strongly induced by chromate or dichromate, but it was completely unresponsive to Cr(III), oxidants, sulfate, or other oxyanions. Plasmid reporter experiments identified ChrB as a chromate-sensing regulator of chr expression. Induction of the chr operon suppressed accumulation of cellular Cr through the activity of a chromate efflux pump encoded by chrA. Expression of chrB, chrC, or chrF in an Escherichia coli sodA sodB double mutant restored its aerobic growth in minimal medium and conferred resistance to superoxide-generating agents menadione and paraquat. Nitroblue tetrazolium staining on native gels showed that ChrC protein had superoxide dismutase activity. TnOtChr appears to represent a mobile genetic system for the distribution of the chromate-regulated resistance operon. The presence of three genes protecting against superoxide toxicity should provide an additional survival advantage to TnOtChr-containing cells in the environments with multiple redox-active contaminants.

  6. Formation of homo- and heterooligomeric supramolecular structures by D-glyceraldehyde-3-phosphate dehydrogenase and lactate dehydrogenase in reversed micelles of aerosol OT in octane.

    PubMed

    Levashov, A V; Ugolnikova, A V; Ivanov, M V; Klyachko, N L

    1997-07-01

    The supramolecular structure of oligomeric enzymes can be specifically regulated by changing the size of an inner cavity of Aerosol OT reversed micelles in octane. Both D-glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and lactate dehydrogenase (LDH) reveal an ability to exist and function in monomeric, dimeric and tetrameric forms (homooligomers). Various heterooligomeric complexes, in particular, GAPDH monomer--LDH monomer, GAPDH dimer--LDH tetramer were detected in reversed micelles.

  7. Perovskite LaFeO3 nanoparticles synthesized by the reverse microemulsion nanoreactors in the presence of aerosol-OT: Morphology, crystal structure, and their optical properties

    NASA Astrophysics Data System (ADS)

    Abazari, Reza; Sanati, Soheila

    2013-12-01

    Orthorhombic structure of lanthanum ferrite nanoparticles (LaFeO3 NPs) with perovskite type phase has been synthesized with water-in-oil (W/O) microemulsion consisted of water/dioctyl sulfosuccinate sodium (aerosol-OT)/isooctane at room temperature. It has been shown that aerosol-OT reverse microemulsion solution is appropriate for synthesizing perovskite LaFeO3 NPs in the absence of any co-surfactants. Field emission scanning electron microscope (FE-SEM), transmission electron microscopy (TEM), energy dispersive analysis of X-ray (EDAX), X-ray diffraction (XRD), ultraviolet-visible absorption spectroscopy (UV-Vis), and Fourier transform infrared spectroscopy (FT-IR) have been adopted for characterization of surface morphology, size, phase composition, structure, and optical properties of the considered NPs. Furthermore, the optical properties of LaFeO3 NPs have been further analyzed via photoluminescence (PL) spectroscopy. As shown by the physicochemical characterizations, our prepared NPs via aerosol-OT reverse microemulsion solution are spherical and nearly uniform (with a size of about 24.65 nm). Besides, they include an orthorhombic phase while no impurities are observed. Single phase lanthanum ferrite NPs have successfully been prepared at 500 °C. Moreover, UV-Vis spectrum indicates that the LaFeO3 NPs synthesized through this technique can be considered as a type of photo-catalytic materials.

  8. Automatic parameter adjustment of difference of Gaussian (DoG) filter to improve OT-MACH filter performance for target recognition applications

    NASA Astrophysics Data System (ADS)

    Alkandri, Ahmad; Gardezi, Akber; Bangalore, Nagachetan; Birch, Philip; Young, Rupert; Chatwin, Chris

    2011-11-01

    A wavelet-modified frequency domain Optimal Trade-off Maximum Average Correlation Height (OT-MACH) filter has been trained using 3D CAD models and tested on real target images acquired from a Forward Looking Infra Red (FLIR) sensor. The OT-MACH filter can be used to detect and discriminate predefined targets from a cluttered background. The FLIR sensor extends the filter's ability by increasing the range of detection by exploiting the heat signature differences between the target and the background. A Difference of Gaussians (DoG) based wavelet filter has been use to improve the OT-MACH filter discrimination ability and distortion tolerance. Choosing the right standard deviation values of the two Gaussians comprising the filter is critical. In this paper we present a new technique for auto adjustment of the DoG filter parameters driven by the expected target size. Tests were carried on images acquired by the Apache AH-64 helicopter mounted FLIR sensor, results showing an overall improvement in the recognition of target objects present within the IR images.

  9. Transcriptional Gene Silencing Maintained by OTS1 SUMO Protease Requires a DNA-Dependent Polymerase V-Dependent Pathway1[OPEN

    PubMed Central

    Liu, Lei; Yan, Xiaojing; Zhao, Yiqiang

    2017-01-01

    The expression of genes with aberrant structure is prevented at both the transcriptional and posttranscriptional regulation levels. Aberrant gene silencing at the posttranscriptional level is well studied; however, it is not well understood how aberrant genes are silenced at the transcriptional level. In this study, through genetic screening a transgenic report line that harbors an aberrant gene (35S-LUC, lacking 3′-untranslated region [3′-UTR]) and lacks luciferase (LUC) activity, we identify that the small ubiquitin-like modifier (SUMO) protease OTS1 gene is required for maintaining the silence of the reporter 35S-LUC and an endogenous mutator-like element MULE-F19G14 at the transcriptional level, which requires DNA-dependent RNA polymerase (Pol) V and DDR complex, but not Pol IV. The increased transcripts in ots1 mutants are terminated by the 3′-UTRs of downstream genes. In addition to ots1 mutations, mutations in several known or putative SUMO proteases and two SUMO E3 ligases, SIZ1 and MMS21, have similar effects on this silencing regulation. Taken together, our results reveal that the enzymes involved in the SUMOylation process restrain aberrant gene transcription by using a downstream gene 3′-UTR, and this regulation requires a functional Pol V-dependent pathway in Arabidopsis (Arabidopsis thaliana). PMID:27852949

  10. Synthesis and Characterization of Et2NM OB[Si(OtBu)3]2 3 (M=Zr,Hf) Molecular Precursors to Zr/B/Si/O and Hf/B/Si/O Materials

    SciTech Connect

    Fujdala, Kyle L.; Tilley, T. Don

    2005-03-18

    Two new transition metal complexes containing the -OB[OSi(OtBu)3]2 ligand, Et2NM{l_brace}OB[OSi(OtBu)3]2{r_brace}3 (M = Zr, Hf), are reported. These species are the 4th and 5th examples of complexes containing this recently reported borosiloxide ligand. Their use as potential molecular precursors to multi-component oxide materials via the thermolytic molecular precursor (TMP) method is discussed.

  11. Simultaneous Photometry and Spectroscopy of the Deeply Absorbing Polar MASTER OT J132104.04+560957.8

    NASA Astrophysics Data System (ADS)

    Hoyt, Taylor; Littlefield, Colin; Garnavich, Peter M.

    2016-01-01

    We present photometry and time-resolved spectroscopy of the suspected polar MASTER OT J132104.04+560957.8 (J1321) taken at the Large Binocular Telescope (LBT) simultaneously with the LBC camera and MODS spectrograph in binocular mode. Our V-band photometry confirmed a primary and secondary maximum first identified by Littlefield et al. In the spectra we see unusually deep Balmer and helium absorption features for about 10-15% of a 91 minute orbital period. The absorption lines first appear to the red of the emission peaks then shift bluewards, ultimately dominating the line profile at zero radial velocity. Towards the end of the absorption phase, weak absorption reappears to the blue of the emission lines. When the system is bright the spectra show a broadly-peaked continuum with a maximum around 500nm. We do not see absorption during the secondary bright red phase. Around the minima the continuum is blue and resembles a more typical polar spectrum with strong Balmer, neutral helium and ionized helium emission lines. The Doppler tomograms of J1321 are fuzzy and blobby and resemble those of the asynchronous polar BY Cam. The highly variable width of the secondary maximum remains a mystery along with the lack of a discernible irradiated secondary in the tomograms. We use our observations to constrain the properties of the white dwarf's magnetic field as well as the accretion flow structure. We also discuss evidence of J1321 being in a prolonged low-mass-transfer state in all observations prior to 2007.

  12. Characterisation of microstructures formed in isopropyl palmitate/water/Aerosol OT:1-butanol (2:1) system.

    PubMed

    Boonme, P; Krauel, K; Graf, A; Rades, T; Junyaprasert, V B

    2006-11-01

    The aim of this work was to determine the type and microstructure of microemulsion samples formed in IPP/water/AerosolOT:1-butanol (2:1) systems as a case study for the investigation of microemulsions. The concentration of the surfactant/cosurfactant mixture was kept constant while the ratio of water to oil was varied. Several techniques were used to investigate the types and phase transitions of the microemulsion formulations. The experimental methods used included visual observation cross-polarized light microscopy (PLM) appearance, conductivity, viscosity, cryo-field emission scanning electron microscopy (cryo-FESEM), differential scanning calorimetry (DSC), nuclear magnetic resonance (NMR), and fluorescence resonance energy transfer (FRET). Taken together, the results of the various techniques imply that the systems investigated are undergoing two transitions as a function of water concentration. Between 10-15%w/w of water, the systems change from headgroup hydrated surfactant solutions in oil (or possibly very small reversed micellar systems) to w/o microemulsions. These systems then change to o/w microemulsions between 25-30%w/w of water. The transitions however, appear to be gradual, as for example the DSC data indicates a transition between 15-20%w/w of water. Furthermore, for some methods the changes observed were very weak, and only with supportive data of other techniques can the phase behaviour of the microemulsion systems be interpreted with confidence. Interestingly, no indication of the presence of a bicontinuous intermediate microstructure was found. Liquid crystal formation was detected in samples containing 55%w/w of water.

  13. ADP-dependent 6-Phosphofructokinase from Pyrococcus horikoshii OT3: STRUCTURE DETERMINATION AND BIOCHEMICAL CHARACTERIZATION OF PH1645

    SciTech Connect

    Currie, Mark A.; Merino, Felipe; Skarina, Tatiana; Wong, Andrew H.Y.; Singer, Alexander; Brown, Greg; Savchenko, Alexei; Caniuguir, Andrés; Guixé, Victoria; Yakunin, Alexander F.; Jia, Zongchao

    2009-12-01

    Some hyperthermophilic archaea use a modified glycolytic pathway that employs an ADP-dependent glucokinase (ADP-GK) and an ADP-dependent phosphofructokinase (ADP-PFK) or, in the case of Methanococcus jannaschii, a bifunctional ADP-dependent glucophosphofructokinase (ADP-GK/PFK). The crystal structures of three ADP-GKs have been determined. However, there is no structural information available for ADP-PFKs or the ADP-GK/PFK. Here, we present the first crystal structure of an ADP-PFK from Pyrococcus horikoshii OT3 (PhPFK) in both apo- and AMP-bound forms determined to 2.0-{angstrom} and 1.9-{angstrom} resolution, respectively, along with biochemical characterization of the enzyme. The overall structure of PhPFK maintains a similar large and small {alpha}/{beta} domain structure seen in the ADP-GK structures. A large conformational change accompanies binding of phosphoryl donor, acceptor, or both, in all members of the ribokinase superfamily characterized thus far, which is believed to be critical to enzyme function. Surprisingly, no such conformational change was observed in the AMP-bound PhPFK structure compared with the apo structure. Through comprehensive site-directed mutagenesis of the substrate binding pocket we identified residues that were critical for both substrate recognition and the phosphotransfer reaction. The catalytic residues and many of the substrate binding residues are conserved between PhPFK and ADP-GKs; however, four key residues differ in the sugar-binding pocket, which we have shown determine the sugar-binding specificity. Using these results we were able to engineer a mutant PhPFK that mimics the ADP-GK/PFK and is able to phosphorylate both fructose 6-phosphate and glucose.

  14. Other Transaction (OT) Authority

    DTIC Science & Technology

    2008-11-25

    Thomas Cellucci posted on the IEEE website for a homeland security conference it sponsored, DHS appointed Thomas Cellucci to a five-year “administrative...Technology Directorate, Thomas A. Cellucci , PhD, MBA, Chief Commercialization Officer,” n.d., available at [http...www.ieeehomelandsecurityconference.org/biography/ Cellucci %20Bio-DHS_2%20_casual_.pdf].) The original name of this organization, IEEE, was the Institute of Electrical and Electronics

  15. A dimeric molecular precursor [(tBuO)2Ti mu-O2Si[OSi(OtBu)3]2]2to Ti(IV)/SiO2 catalysts for selective cyclohexene epoxidation

    SciTech Connect

    Brutchey, Richard L.; Mork, Benjamin V.; Sirbuly, Donald J.; Yang, Peidong; Tilley, T. Don

    2005-04-20

    The new dimeric complex [(tBuO)2Ti({mu}-O2Si[OSi(OtBu)3]2)]2 (1), prepared via silanolysis of Ti(OtBu)4 with (HO)2Si[OSi(OtBu)3]2, is a structural and spectroscopic (NMR, FT-IR, UV-vis, XPS) model for Ti(IV)/SiO2. The molecular complex was used to prepare titanium-containing silica materials through both the thermolytic molecular precursor method (yielding TiO2{center_dot}3SiO2) or by grafting 1 onto mesoporous SBA-15 silica. Grafting 1 onto SBA-15 yields mostly isolated Ti(IV) sites, as evidenced by DRUV-vis and photoluminescence spectroscopies. The resulting materials were found to be active and highly selective in the epoxidation of cyclohexene, yielding up to 71% of cyclohexene oxide based on oxidant (cumene hydroperoxide) after 2 h at 65 C in toluene.

  16. Growth of a radiation-transformed clone of C3H 1OT1/2 cells into melanin-producing colonies

    SciTech Connect

    Szekely, J.G.; Raaphorst, G.P.; Lobreau, A.U.; Azzam, E.I.; Vadasz, J.A.

    1985-01-01

    When R25, a radiation-transformed clone of C3H 1OT1/2 cells, was plated in soft agarose, a fraction of the colonies became pigmented. The morphologies of the white and dark colonies and their cells were compared by optical, transmission and scanning electron microscopy. The transformed R25 cells had apparently differentiated into melanin-producing cells in the soft agarose, with the white colonies containing actively growing cells having only a few melanosomes, and the dark colonies being made up of stationary-phase cells filled with electronopaque melanosomes. Exposure of the R25 cells to 4.0 Gy of X-rays decreased the percentage of dark colonies, while exposure to 1% DMSO had no effect.

  17. FLOYDS Classification of MASTER OT J161308.18+260953.3 as a Type II Supernova and ASASSN-17cq/AT 2017axl as a Type Ia Supernova Near Peak

    NASA Astrophysics Data System (ADS)

    Hosseinzadeh, G.; Arcavi, I.; Howell, D. A.; McCully, C.; Valenti, S.

    2017-02-01

    We obtained a spectrum of MASTER OT J161308.18+260953.3 (ATel #10099) on 2017 February 21.5 UT with the robotic FLOYDS instrument mounted on the Las Cumbres Observatory (LCO) 2-meter telescope on Haleakala, Hawai'i.

  18. RACK-1, a multifaceted regulator is required for C. elegans innate immunity against S. flexneri M9OT infection.

    PubMed

    Marudhupandiyan, Shanmugam; Prithika, Udayakumar; Balasubramaniam, Boopathi; Balamurugan, Krishnaswamy

    2017-09-01

    The nematode C. elegans has the ability to clear off bacterial colonization in the intestine using pathogen specific innate immune response. Here, we show that C. elegans RACK-1 has been vital in determining the survival of worms under specific pathogenic infection. Among various pathogens tested, S. flexneri M9OT (SF) exhibited highest pathogenicity by killing rack-1 mutant worm-VC3013 earlier when compared to WT. The expression level of rack-1 mRNA was found to be decreased and it further indicated that the host translational event appeared to be affected during SF infection. Hence, inhibition of translational machinery was the foremost reason for the early mortality in C. elegans. Apparently, variation in the expression of RACK-1 affects the activation of p38 and JNK-MAPK pathway which consequently triggered expression of nlp-29 and longevity, respectively. The study unveils novel defense mechanisms exist for C. elegans in facilitating enhanced immunity by RACK-1 against SF infection. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. Discovery of an unusual bright eclipsing binary with the longest known period: TYC 2505-672-1/MASTER OT J095310.04+335352.8

    NASA Astrophysics Data System (ADS)

    Lipunov, V.; Gorbovskoy, E.; Afanasiev, V.; Tatarnikova, A.; Denisenko, D.; Makarov, D.; Tiurina, N.; Krushinsky, V.; Vinokurov, A.; Balanutsa, P.; Kuznetsov, A.; Gress, O.; Sergienko, Yu.; Yurkov, V.; Gabovich, A.; Tlatov, A.; Senik, V.; Vladimirov, V.; Popova, E.

    2016-04-01

    We report on the MASTER Global Robotic Net discovery of an eclipsing binary, MASTER OT J095310.04+335352.8, previously known as unremarkable star TYC 2505-672-1, which displays extreme orbital parameters. The orbital period P = 69.1 yr is more than 2.5 times longer than that of ɛ-Aurigae, which is the previous record holder. The light curve is characterized by an extremely deep total eclipse with a depth of more than 4.5 mag, which is symmetrically shaped and has a total duration of 3.5 yr. The eclipse is essentially gray. The spectra acquired with the Russian 6 m BTA telescope both at minimum and maximum light mainly correspond to an M0-1III-type red giant, but the spectra taken at the bottom of eclipse show small traces of a sufficiently hot source. The observed properties of this system can be better explained as the red giant eclipsed by a large cloud (the disk) of small particles surrounding the invisible secondary companion.

  20. Pressure effects on bending elasticities of surfactant monolayers in a ternary microemulsion composed of aerosol-OT /D2O/decane

    NASA Astrophysics Data System (ADS)

    Kawabata, Youhei; Seto, Hideki; Nagao, Michihiro; Takeda, Takayoshi

    2007-07-01

    Pressure effects on the bending elasticities of surfactant monolayers have been investigated in a microemulsion system composed of aerosol-OT (AOT), D2O, and deuterated decane by means of small angle neutron scattering, neutron spin echo (NSE), and dynamic light scattering (DLS). In this system, a water-in-oil droplet structure, at ambient temperature and pressure, decomposes into two phases, under both increasing temperature and pressure. The authors' previous study showed that the bending modulus κ of monolayers slightly decreased with increasing temperature, while it increased with increasing pressure. Temperature and pressure dependencies of κ were explained in terms of a microscopic model, which takes into account the interactions between surfactant molecules. In this paper, the authors present the temperature and pressure dependencies of κ obtained by the analysis combined with DLS and NSE experiments. The values of the bending modulus and mean displacement of the second-order droplet deformation are reasonable. It was further confirmed that an increase in the attractive interaction between hydrocarbon tails of AOT molecules with increasing pressure could be the origin of the pressure-induced phase transition.

  1. Neutron and X-Ray Reflectivity Studies of the Adsorption of Aerosol-OT at the Air-Water Interface: The Structure of the Calcium Salt

    PubMed

    Li; Lee; Thomas; Penfold

    1997-03-15

    We have used neutron and X-ray reflection to determine the structure of a layer of calcium bis-(2-ethyl 1-hexyl) sulphosuccinate (Aerosol-OT or AOT) adsorbed at the air/solution interface. The widths of the distributions of the chains and head groups of the molecule, and their positions in relation to the underlying water, have been measured at four concentrations varying from the solubility limit (CMC) at 4 x 10(-4) M to 1 x 10(-6) M. Over this concentration range the coverage changes from 68 ± 3 to 142 ± 8 Å2 per AOT unit. The structure of the layer both is quite different from that of NaAOT and varies quite differently with surface concentration. The Ca(AOT)2 layer is slightly (1 Å) further out from the water, but the chain region is thinner for the calcium surfactant. This is reflected most in the greatly reduced chain to head separation, which drops from about 6 Å in NaAOT to about 4 Å in Ca(AOT)2.

  2. Crystallization and preliminary X-ray crystallographic studies of the biotin carboxyl carrier protein and biotin protein ligase complex from Pyrococcus horikoshii OT3

    PubMed Central

    Bagautdinov, Bagautdin; Matsuura, Yoshinori; Bagautdinova, Svetlana; Kunishima, Naoki

    2007-01-01

    Biotin protein ligase (BPL) catalyses the biotinylation of the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase. To elucidate the exact details of the protein–protein interactions in the biotinylation function, the C-terminal half fragment of BCCP (BCCPΔN76), the R48A mutant of BPL (BPL*) and the R48A K111A double mutant of BPL (BPL**), all of which are from Pyrococcus horikoshii OT3, have been expressed, purified and successfully cocrystallized. Cocrystals of the BPL*–BCCPΔN76 and BPL**–BCCPΔN76 complexes as well as crystals of BPL*, BPL** and BCCPΔN76 were obtained by the oil-microbatch method using PEG 20 000 as a precipitant at 295 K. Complete X-ray diffraction data sets for BPL*–BCCPΔN76 and BPL**–BCCPΔN76 crystals were collected at 100 K to 2.7 and 2.0 Å resolution, respectively, using synchrotron radiation. They belong to the monoclinic space group P21, with similar unit-cell parameters a = 69.85, b = 63.12, c = 75.64 Å, β = 95.9°. Assuming two subunits of the complex per asymmetric unit gives a V M value of 2.45 Å3 Da−1 and a solvent content of 50%. PMID:17401210

  3. Crystallization and preliminary X-ray crystallographic studies of the biotin carboxyl carrier protein and biotin protein ligase complex from Pyrococcus horikoshii OT3.

    PubMed

    Bagautdinov, Bagautdin; Matsuura, Yoshinori; Bagautdinova, Svetlana; Kunishima, Naoki

    2007-04-01

    Biotin protein ligase (BPL) catalyses the biotinylation of the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase. To elucidate the exact details of the protein-protein interactions in the biotinylation function, the C-terminal half fragment of BCCP (BCCPDeltaN76), the R48A mutant of BPL (BPL*) and the R48A K111A double mutant of BPL (BPL**), all of which are from Pyrococcus horikoshii OT3, have been expressed, purified and successfully cocrystallized. Cocrystals of the BPL*-BCCPDeltaN76 and BPL**-BCCPDeltaN76 complexes as well as crystals of BPL*, BPL** and BCCPDeltaN76 were obtained by the oil-microbatch method using PEG 20 000 as a precipitant at 295 K. Complete X-ray diffraction data sets for BPL*-BCCPDeltaN76 and BPL**-BCCPDeltaN76 crystals were collected at 100 K to 2.7 and 2.0 A resolution, respectively, using synchrotron radiation. They belong to the monoclinic space group P2(1), with similar unit-cell parameters a = 69.85, b = 63.12, c = 75.64 A, beta = 95.9 degrees . Assuming two subunits of the complex per asymmetric unit gives a V(M) value of 2.45 A(3) Da(-1) and a solvent content of 50%.

  4. MASTER OT J004207.99+405501.1/M31LRN 2015 luminous red nova in M31: discovery, light curve, hydrodynamics and evolution

    NASA Astrophysics Data System (ADS)

    Lipunov, V. M.; Blinnikov, S.; Gorbovskoy, E.; Tutukov, A.; Baklanov, P.; Krushinski, V.; Tiurina, N.; Balanutsa, P.; Kuznetsov, A.; Kornilov, V.; Gorbunov, I.; Shumkov, V.; Vladimirov, V.; Gress, O.; Budnev, N. M.; Ivanov, K.; Tlatov, A.; Gabovich, A.; Yurkov, V.; Sergienko, Yu.; Zalozhnykh, I.

    2017-09-01

    We report the discovery and multicolour (VRIW) photometry of the rare explosive star MASTER OT J004207.99+405501.1 - a luminous red nova - in the Andromeda galaxy M31N2015-01a. We use our original light curve acquired with identical MASTER Global Robotic Net telescopes in one photometric system: VRI during the first 30 d and W (unfiltered) during 70 d. Also, we added published multicolour photometry data to estimate the mass and energy of the ejected shell and we discuss the likely formation scenarios of outbursts of this type. We propose an interpretation of the explosion that is consistent with an evolutionary scenario where the merging of stellar components or the disruption of the common envelope of a close binary can explain some luminous red novae. Radiative hydrodynamic simulations of a luminous red nova were carried out in extended parameter space to fit its light curves. We find that the multicolour passband light curves of the luminous red nova are consistent with an initial common envelope radius of 10 R⊙, a merger mass of 3 M⊙ and an explosion energy of 3 × 1048 erg. As a result, the phenomenon of novae consists of two classes: classical nuclear novae and more rare events (red novae) connected with the loss of compact common envelopes.

  5. Evaluation of the efficiency of tumor and tissue delivery of carrier-mediated agents (CMA) and small molecule (SM) agents in mice using a novel pharmacokinetic (PK) metric: relative distribution index over time (RDI-OT)

    NASA Astrophysics Data System (ADS)

    Madden, Andrew J.; Rawal, Sumit; Sandison, Katie; Schell, Ryan; Schorzman, Allison; Deal, Allison; Feng, Lan; Ma, Ping; Mumper, Russell; DeSimone, Joseph; Zamboni, William C.

    2014-11-01

    The pharmacokinetics (PK) of carrier-mediated agents (CMA) is dependent upon the carrier system. As a result, CMA PK differs greatly from the PK of small molecule (SM) drugs. Advantages of CMAs over SMs include prolonged circulation time in plasma, increased delivery to tumors, increased antitumor response, and decreased toxicity. In theory, CMAs provide greater tumor drug delivery than SMs due to their prolonged plasma circulation time. We sought to create a novel PK metric to evaluate the efficiency of tumor and tissue delivery of CMAs and SMs. We conducted a study evaluating the plasma, tumor, liver, and spleen PK of CMAs and SMs in mice bearing subcutaneous flank tumors using standard PK parameters and a novel PK metric entitled relative distribution over time (RDI-OT), which measures efficiency of delivery. RDI-OT is defined as the ratio of tissue drug concentration to plasma drug concentration at each time point. The standard concentration versus time area under the curve values (AUC) of CMAs were higher in all tissues and plasma compared with SMs. However, 8 of 17 SMs had greater tumor RDI-OT AUC0-last values than their CMA comparators and all SMs had greater tumor RDI-OT AUC0-6 h values than their CMA comparators. Our results indicate that in mice bearing flank tumor xenografts, SMs distribute into tumor more efficiently than CMAs. Further research in additional tumor models that may more closely resemble tumors seen in patients is needed to determine if our results are consistent in different model systems.

  6. Evaluation of the efficiency of tumor and tissue delivery of carrier-mediated agents (CMA) and small molecule (SM) agents in mice using a novel pharmacokinetic (PK) metric: relative distribution index over time (RDI-OT).

    PubMed

    Madden, Andrew J; Rawal, Sumit; Sandison, Katie; Schell, Ryan; Schorzman, Allison; Deal, Allison; Feng, Lan; Ma, Ping; Mumper, Russell; DeSimone, Joseph; Zamboni, William C

    2014-11-01

    The pharmacokinetics (PK) of carrier-mediated agents (CMA) is dependent upon the carrier system. As a result, CMA PK differs greatly from the PK of small molecule (SM) drugs. Advantages of CMAs over SMs include prolonged circulation time in plasma, increased delivery to tumors, increased antitumor response, and decreased toxicity. In theory, CMAs provide greater tumor drug delivery than SMs due to their prolonged plasma circulation time. We sought to create a novel PK metric to evaluate the efficiency of tumor and tissue delivery of CMAs and SMs. We conducted a study evaluating the plasma, tumor, liver, and spleen PK of CMAs and SMs in mice bearing subcutaneous flank tumors using standard PK parameters and a novel PK metric entitled relative distribution over time (RDI-OT), which measures efficiency of delivery. RDI-OT is defined as the ratio of tissue drug concentration to plasma drug concentration at each time point. The standard concentration versus time area under the curve values (AUC) of CMAs were higher in all tissues and plasma compared with SMs. However, 8 of 17 SMs had greater tumor RDI-OT AUC0-last values than their CMA comparators and all SMs had greater tumor RDI-OT AUC0-6 h values than their CMA comparators. Our results indicate that in mice bearing flank tumor xenografts, SMs distribute into tumor more efficiently than CMAs. Further research in additional tumor models that may more closely resemble tumors seen in patients is needed to determine if our results are consistent in different model systems.

  7. EPA/ORD/RTP (Environmental Protection Agency, Office of Research and Development, Research Triangle Park) asbestos program support for the OTS (Office of Toxic Substances) asbestos-in-schools program. Final report

    SciTech Connect

    Beard, M.E.

    1986-03-01

    An overview of the EPA/ORD/RTP Asbestos program support for the OTS Asbestos-in-Schools Program is given. The program includes (1) a bulk sample asbestos analysis audit program, (2) an intercomparison of three measurement methods for airborne asbestos, (3) the development of audit materials for airborne asbestos measurement methods, and (4) the development of guidance for post-abatement asbestos air monitoring.

  8. Behavioral responses to pups in males with different reproductive experiences are associated with changes in central OT, TH and OTR, D1R, D2R mRNA expression in mandarin voles.

    PubMed

    Wang, Bo; Li, Yani; Wu, Ruiyong; Zhang, Shuwei; Tai, Fadao

    2015-01-01

    Male rodents behave differently toward pups because of different sexual and/or paternal experiences; however, the mechanisms underlying these responses are not well understood. Using socially monogamous mandarin voles (Microtus mandarinus) we investigated the behavioral responses of males with different reproductive experiences (virgin males, paired males and new fathers) to new born pups. Central levels of neuropeptide oxytocin (OT), tyrosine hydroxylase (TH), as well as oxytocin receptor (OTR), dopamine 1-type receptor (D1R) and dopamine 2-type receptor (D2R) mRNA expression in the nucleus accumbens and medial amygdala were also measured in these males. Our data showed that new fathers exhibited more approaching behavior and contained more OT-immunoreactive and TH-immunoreactive neurons. In addition to increased OTR mRNA expression in the nucleus accumbens and medial amygdala, new fathers had higher D1R and D2R mRNA expression in the nucleus accumbens, and less D1R and D2R mRNA expression in the medial amygdala than paired males. These results demonstrate that males with different reproductive experiences display different behavioral responses to pups and that these differences are associated with altered OT and dopamine, and their receptors in specific brain regions.

  9. Ries Bunte Breccia revisited: Indications for the presence of water in Itzing and Otting drill cores and implications for the emplacement process

    NASA Astrophysics Data System (ADS)

    Pietrek, Alexa; Kenkmann, Thomas

    2016-07-01

    We reassessed two drill cores of the Bunte Breccia deposits of the Ries crater, Germany. The objectives of our study were the documentation of evidence for water in the Bunte Breccia, the evaluation of how that water influenced the emplacement processes, and from which preimpact water reservoir it was derived. The Bunte Breccia in both cores can be structured into a basal layer composed mainly of local substrate material, overlain by texturally and compositionally diverse, crater-derived breccia units. The basal layer is composed of the youngest sediments (Tertiary clays and Upper Jurassic limestone) and has a razor-sharp boundary to the upper breccia units, which are composed of older rocks of Upper Jurassic to Upper Triassic age. Sparse material exchange occurred between the basal layer and the rest of the Bunte Breccia. Fluids predominantly came from the Tertiary and the Upper Triassic sandstone formation. In the basal layer, Tertiary clays were subjected to intense, ductile deformation, indicating saturation with water. This suggests that water was mixed into the matrix, creating a fluidized basal layer with a strong shear localization. In the upper units, Upper Triassic sandstones are intensely deformed by granular flow. The texture requires that the rocks were disaggregated into granular sand. Vaporization of pore water probably aided fragmentation of these rocks. In the Otting core, hot suevite (T > 600 °C) covered the Bunte Breccia shortly after its emplacement. Vertically oriented gas escape pipes in suevite partly emanate directly at the contact to the Bunte Breccia. They indicate that the Bunte Breccia contained a substantial amount of water in the upper part that was vaporized and escaped through these vents.

  10. OT2_sserje01_2: THE HERSCHEL-AKARI NEP DEEP SURVEY: the cosmological history of stellar mass assembly and black hole accretion

    NASA Astrophysics Data System (ADS)

    Serjeant, S.

    2011-09-01

    We propose a far-IR and submm mapping survey of the premier AKARI deep field in the North Ecliptic Pole, in PACS/SPIRE parallel mode. This is the only major deep infrared field not yet covered by Herschel guaranteed or open time key projects. The outstanding and unparalleled continuous mid-IR photometric coverage from AKARI, far better than equivalent Spitzer surveys, enables a wide range of galaxy evolution diagnostics unachievable in any other survey field (including Herschel HerMES/PEP fields), by spanning the wavelengths of redshifted PAH and silicate features and the peak energy output of AGN dust tori. The investment by AKARI in the NEP represents ~10 percent of the entire pointed observations available throughout the lifetime of AKARI. Our proposal remedies the remarkable omission from Herschel's legacy surveys of the premier extragalactic deep field from another IR space telescope. We will simultaneously identify and find photometric redshifts for the Herschel point source population, make stacking analysis detections of the galaxies which dominate the submm extragalactic background light as a function of redshift, determine the bolometric power outputs of the galaxies that dominate the submm background, compare the UV/optical/mid-IR continuum/PAH/far-IR/submm/radio star formation rate estimator in the most comprehensive IR survey data set to date, and track the coupled stellar mass assembly and black hole accretion throughout most of the history of the Universe. In OT1 the HOTAC concluded "The science output from the proposed survey will be outstanding [...] The panel was convinced that these observations should be done" but it since became clear that priority 2 time is very unlikely to be executed, so we request reclassification to priority 1.

  11. Identification of a novel amino acid racemase from a hyperthermophilic archaeon Pyrococcus horikoshii OT-3 induced by D-amino acids.

    PubMed

    Kawakami, Ryushi; Ohmori, Taketo; Sakuraba, Haruhiko; Ohshima, Toshihisa

    2015-08-01

    To date, there have been few reports analyzing the amino acid requirement for growth of hyperthermophilic archaea. We here found that the hyperthermophilic archaeon Pyrococcus horikoshii OT-3 requires Thr, Leu, Val, Phe, Tyr, Trp, His and Arg in the medium for growth, and shows slow growth in medium lacking Met or Ile. This largely corresponds to the presence, or absence, of genes related to amino acid biosynthesis in its genome, though there are exceptions. The amino acid requirements were dramatically lost by addition of D-isomers of Met, Leu, Val, allo-Ile, Phe, Tyr, Trp and Arg. Tracer analysis using (14)C-labeled D-Trp showed that D-Trp in the medium was used as a protein component in the cells, suggesting the presence of D-amino acid metabolic enzymes. Pyridoxal 5'-phosphate (PLP)-dependent racemase activity toward Met, Leu and Phe was detected in crude extract of P. horikoshii and was enhanced in cells grown in the medium supplemented with D-amino acids, especially D-allo-Ile. The gene encoding the racemase was narrowed down to one open reading frame on the basis of enzyme purification from P. horikoshii cells, and the recombinant enzyme exhibited PLP-dependent racemase activity toward several amino acids, including Met, Leu and Phe, but not Pro, Asp or Glu. This is the first report showing the presence in a hyperthermophilic archaeon of a PLP-dependent amino acid racemase with broad substrate specificity that is likely responsible for utilization of D-amino acids for growth.

  12. Crystallization and preliminary X-ray crystallographic studies of the biotin carboxyl carrier protein and biotin protein ligase complex from Pyrococcus horikoshii OT3

    SciTech Connect

    Bagautdinov, Bagautdin; Matsuura, Yoshinori; Bagautdinova, Svetlana; Kunishima, Naoki

    2007-04-01

    A truncated form of biotin carboxyl carrier protein containing the C-terminal half fragment (BCCPΔN76) and the biotin protein ligase (BPL) with the mutation R48A (BPL*) or the double mutation R48A K111A (BPL**) were successfully cocrystallized in the presence of ATP and biotin. The BPL*–BCCPΔN76 and BPL**–BCCPΔN76 crystals belong to space group P2{sub 1} and diffract X-rays to 2.7 and 2.0 Å resolution, respectively. Biotin protein ligase (BPL) catalyses the biotinylation of the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase. To elucidate the exact details of the protein–protein interactions in the biotinylation function, the C-terminal half fragment of BCCP (BCCPΔN76), the R48A mutant of BPL (BPL*) and the R48A K111A double mutant of BPL (BPL**), all of which are from Pyrococcus horikoshii OT3, have been expressed, purified and successfully cocrystallized. Cocrystals of the BPL*–BCCPΔN76 and BPL**–BCCPΔN76 complexes as well as crystals of BPL*, BPL** and BCCPΔN76 were obtained by the oil-microbatch method using PEG 20 000 as a precipitant at 295 K. Complete X-ray diffraction data sets for BPL*–BCCPΔN76 and BPL**–BCCPΔN76 crystals were collected at 100 K to 2.7 and 2.0 Å resolution, respectively, using synchrotron radiation. They belong to the monoclinic space group P2{sub 1}, with similar unit-cell parameters a = 69.85, b = 63.12, c = 75.64 Å, β = 95.9°. Assuming two subunits of the complex per asymmetric unit gives a V{sub M} value of 2.45 Å{sup 3} Da{sup −1} and a solvent content of 50%.

  13. Aerodynamic results of an abort separation effects test (IA8) conducted in the NASA/ARC 14-foot transonic wind tunnel on a model (6-OTS) of the Rockwell International launch configuration integrated vehicle

    NASA Technical Reports Server (NTRS)

    Campbell, J. H.

    1974-01-01

    Experimental aerodynamic investigations were conducted on a 6-OTS 0.015-scale model. The Ames dual sting support separation rig was used to obtain grid-type data for tank-booster abort from orbiter (SSV). Freestream data were obtained for the orbiter to provide a baseline for evaluation of proximity effects. Data were obtained at Mach numbers from 0.32 to 1.1, and Reynolds number per foot varying from 2.1 million to 3.9 million. Data are not presented. Because of balance failure, a very substantial portion of the test was run with a dummy balance in the tank boosters configuration.

  14. An investigation in the MSFC TWT to determine spoiler effects on wing loads and elevon hinge moments utilizing 0.004-scale models (77-0 and 74-OTS) of the shuttle vehicle 5 configuration (IA125)

    NASA Technical Reports Server (NTRS)

    Allen, E. C.

    1976-01-01

    Information is presented for wind tunnel tests (IA125) of a 0.004-scale orbiter, external tank, and solid rocket motor integrated vehicle model (77-0 and 74-OTS) in the MSFC Trisonic Wind Tunnel. These tests were conducted in support of MCR's 1344 and 1346. Data from these tests provide spoiler effects on wing bending/torsion and elevon hinge moments, elevon effectiveness data and the influence of solid plumes from Mach numbers of 0.6 through 2.74 at angles of attack and sideslip from -10 through 10 degrees.

  15. Aerodynamic results of a separation effects test on a 0.010-scale model (52-OTS) of the integrated SSV in the AEDC/VKF 40-by-40 inch supersonic wind tunnel A (IA111), volume 2

    NASA Technical Reports Server (NTRS)

    Chee, E.

    1976-01-01

    Tabular data obtained during experimental wind tunnel aerodynamic investigations of a 0.010 scale model (52-OTS) of the integrated space shuttle vehicle was presented. The purpose of this investigation was to obtain data with the solid rocket booster (SRB) in proximity to the orbiter/external tank (O/ET), over a large O/ET initial angle of attack and sideslip range, as well as data on the SRB alone (greatly separated from the O/ET). A captive trajectory system, which supported the SRB, was used with the tunnel primary sector (supporting the O/ET) to obtain grid type separation effects data. One symmetrical SRB model was used interchangeably to obtain right-hand and left-hand SRB data. The entire investigation was conducted at free-stream Mach number of 4.5 at unit Reynolds number of 3.95 and 5.9 million per foot.

  16. Results of an investigation of the space shuttle integrated vehicle aerodynamic heating characteristics obtained using the 0.0175-scale model 60-OTS in AEDC tunnel A during tests IH41 and IH41A

    NASA Technical Reports Server (NTRS)

    Cummings, J. W.; Dye, W. H.

    1977-01-01

    A thin skin thermocouple test was conducted to obtain heat-transfer data on the space shuttle integrated vehicle during the ascent phase of the flight profile. The test model was the 0.0175-scale thin skin thermocouple model (60-OTS) of the Rockwell International vehicle 5 configuration. The test was conducted at nominal Mach numbers of 2.5, 3.5, 4.5, and 5.5, and a free stream unit Reynolds number of 5 million per ft. Heat transfer data were obtained for angles of attack of 0, + or - 5, and 10 deg and yaw angles of 0, 3, and 6 deg. The integrated vehicle model was tested with the external tank configured with both a smooth ogive nose and an ogive nose with a spherical nose tip (nipple nose). The remainder of the test was conducted with the external tank installed alone in the tunnel.

  17. An experimental determination in Calspan Ludwieg tube of the base environment of the integrated space shuttle vehicle at simulated Mach 4.5 flight conditions (test IH5 of model 19-OTS)

    NASA Technical Reports Server (NTRS)

    Drzewiecki, R. F.; Foust, J. W.

    1976-01-01

    A model test program was conducted to determine heat transfer and pressure distributions in the base region of the space shuttle vehicle during simulated launch trajectory conditions of Mach 4.5 and pressure altitudes between 90,000 and 210,000 feet. Model configurations with and without the solid propellant booster rockets were examined to duplicate pre- and post-staging vehicle geometries. Using short duration flow techniques, a tube wind tunnel provided supersonic flow over the model. Simultaneously, combustion generated exhaust products reproduced the gasdynamic and thermochemical structure of the main vehicle engine plumes. Heat transfer and pressure measurements were made at numerous locations on the base surfaces of the 19-OTS space shuttle model with high response instrumentation. In addition, measurements of base recovery temperature were made indirectly by using dual fine wire and resistance thermometers and by extrapolating heat transfer measurements.

  18. Aerodynamic results of a separation effects test on a 0.010-scale model (52-OTS) of the integrated SSV in the AEDC/VKF 40-by-40 inch supersonic wind tunnel A (IA111), volume 1

    NASA Technical Reports Server (NTRS)

    Chee, E.

    1976-01-01

    Graphical data obtained during experimental wind tunnel aerodynamic investigations of a 0.010 scale model (52-OTS) of the integrated space shuttle vehicle was presented. The purpose of this investigation was to obtain data with the solid rocket booster (SRB) in proximity to the orbiter/external tank (O/ET), over a large O/ET initial angle of attack and sideslip range, as well as data on the SRB alone (greatly separated from the O/ET). A captive trajectory system, which supported the SRB, was used with the tunnel primary sector (supporting the O/ET) to obtain grid type separation effects data. One symmetrical SRB model was used interchangeably to obtain right-hand and left-hand SRB data. The entire investigation was conducted at a free-stream Mach number of 4.5 at unit Reynolds number of 3.95 and 5.9 million per foot.

  19. Heat transfer tests of an 0.006-scale thin-skin space shuttle thermocouple model (41-OTS) in the Langley Research Center unitary plan wind tunnel at M equals 3.7 (IH16)

    NASA Technical Reports Server (NTRS)

    Walstad, D. G.

    1975-01-01

    The results are presented of supersonic heat transfer tests performed on the .006 scale space shuttle vehicle model (41-OTS) in the Langley Research Center Unitary Plan Wind Tunnel. These tests were conducted to parametrically investigate ascent heating of the integrated vehicle and its components. The tests were conducted at a nominal Mach number of 3.7 and Reynolds numbers per foot of 2 and 5 million. The model configurations investigated were the integrated vehicle and each component alone (i.e. orbiter, tank and SRB). All the configurations were run with and without transition strips and through an angle of attack range of 0 deg to minus 5 deg with the exception of the SRB which was tested through an angle of attack range of minus 5 deg to 90 deg. The heat transfer data were obtained from 223 iron constantan thermocouples attached to stainless steel thin-skin areas of the model.

  20. Results of investigations conducted in the LaRC 4-foot unitary plan wind tunnel leg no. 1 using the 0.010-scale 72-OTS model of the space shuttle integrated vehicle (IA94A)

    NASA Technical Reports Server (NTRS)

    Nichols, M. E.

    1976-01-01

    Aero-loads investigations were conducted on the updated configuration-5 space shuttle launch vehicle at Mach numbers 2.50, 3.50, and 4.50. Six-component vehicle forces and moments, base and sting-cavity pressures, elevon hinge moments, wing-root bending and torsion moments, and normal shear force data were obtained. Full simulation of updated vehicle protuberances and attach hardware was employed. Various elevon deflection angles were tested, with two different forward orbiter-to-external-tank attach-strut configurations. The entire vehicle model 72-OTS was supported by means of a balance mounted in the orbiter through its base and suspended from an appropriate sting for the specific tunnel.

  1. Investigations of the 0.020-scale 88-OTS Integrated Space Shuttle Vehicle Jet-Plume Model in the NASA/Ames Research Center 11 by11-Foot Unitary Plan Wind Tunnel (IA80). Volume 1

    NASA Technical Reports Server (NTRS)

    Nichols, M. E.

    1976-01-01

    The results are documented of jet plume effects wind tunnel test of the 0.020-scale 88-OTS launch configuration space shuttle vehicle model in the 11 x 11 foot leg of the NASA/Ames Research Center Unitary Plan Wind Tunnel. This test involved cold gas main propulsion system (MPS) and solid rocket motor (SRB) plume simulations at Mach numbers from 0.6 to 1.4. Integrated vehicle surface pressure distributions, elevon and rudder hinge moments, and wing and vertical tail root bending and torsional moments due to MPS and SRB plume interactions were determined. Nozzle power conditions were controlled per pretest nozzle calibrations. Model angle of attack was varied from -4 deg to +4 deg; model angle of sideslip was varied from -4 deg to +4 deg. Reynolds number was varied for certain test conditions and configurations, with the nominal freestream total pressure being 14.69 psia. Plotted force and pressure data are presented.

  2. Expression of escherichia coli otsA in a Saccharomyces cerevisiae tps1 mutant restores trehalose 6-phosphate levels and partly restores growth and fermentation with glucose and control of glucose influx into glycolysis.

    PubMed

    Bonini, B M; Van Vaeck, C; Larsson, C; Gustafsson, L; Ma, P; Winderickx, J; Van Dijck, P; Thevelein, J M

    2000-08-15

    The TPS1 gene, encoding trehalose-6-phosphate synthase (TPS), exerts an essential control on the influx of glucose into glycolysis in the yeast Saccharomyces cerevisiae. The deletion of TPS1 causes an inability to grow on glucose because of a hyperaccumulation of sugar phosphates and depletion of ATP and phosphate. We show that expression of the Escherichia coli homologue, otsA, in a yeast tps1 mutant results in high TPS activity. Although the trehalose 6-phosphate (Tre6P) level during exponential growth on glucose was at least as high as in a wild-type yeast strain, growth on glucose was only partly restored and the lag phase was much longer. Measurement of the glycolytic metabolites immediately after the addition of glucose showed that in spite of a normal Tre6P accumulation there was still a partial hyperaccumulation of sugar phosphates. Strong elevation of the Tre6P level by the additional deletion of the TPS2 gene, which encodes Tre6P phosphatase, was not able to cause a strong decrease in the sugar phosphate levels in comparison with the wild-type strain. In addition, in chemostat experiments the short-term response to a glucose pulse was delayed, but normal metabolism was regained over a longer period. These results show that Tre6P synthesis from a heterologous TPS enzyme can to some extent restore the control of glucose influx into glycolysis and growth on glucose in yeast. However, they also indicate that the yeast TPS enzyme, as opposed to the E. coli otsA gene product, is able to increase the efficiency of the Tre6P control on glucose influx into yeast glycolysis.

  3. Expression of KCNQ1OT1, CDKN1C, H19, and PLAGL1 and the methylation patterns at the KvDMR1 and H19/IGF2 imprinting control regions is conserved between human and bovine

    PubMed Central

    2012-01-01

    Background Beckwith-Wiedemann syndrome (BWS) is a loss-of-imprinting pediatric overgrowth syndrome. The primary features of BWS include macrosomia, macroglossia, and abdominal wall defects. Secondary features that are frequently observed in BWS patients are hypoglycemia, nevus flammeus, polyhydramnios, visceromegaly, hemihyperplasia, cardiac malformations, and difficulty breathing. BWS is speculated to occur primarily as the result of the misregulation of imprinted genes associated with two clusters on chromosome 11p15.5, namely the KvDMR1 and H19/IGF2. A similar overgrowth phenotype is observed in bovine and ovine as a result of embryo culture. In ruminants this syndrome is known as large offspring syndrome (LOS). The phenotypes associated with LOS are increased birth weight, visceromegaly, skeletal defects, hypoglycemia, polyhydramnios, and breathing difficulties. Even though phenotypic similarities exist between the two syndromes, whether the two syndromes are epigenetically similar is unknown. In this study we use control Bos taurus indicus X Bos taurus taurus F1 hybrid bovine concepti to characterize baseline imprinted gene expression and DNA methylation status of imprinted domains known to be misregulated in BWS. This work is intended to be the first step in a series of experiments aimed at determining if LOS will serve as an appropriate animal model to study BWS. Results The use of F1 B. t. indicus x B. t. taurus tissues provided us with a tool to unequivocally determine imprinted status of the regions of interest in our study. We found that imprinting is conserved between the bovine and human in imprinted genes known to be associated with BWS. KCNQ1OT1 and PLAGL1 were paternally-expressed while CDKN1C and H19 were maternally-expressed in B. t. indicus x B. t. taurus F1 concepti. We also show that in bovids, differential methylation exists at the KvDMR1 and H19/IGF2 ICRs. Conclusions Based on these findings we conclude that the imprinted gene expression of

  4. Results of aeroheating DFI and ET design-data test on a 0.0175-scale model 60-OTS conducted in the Von Karman Gas Dynamics Facility (VKF) 40" supersonic and the 50" hypersonic wind tunnels A and C

    NASA Technical Reports Server (NTRS)

    Marroquin, J.; Leef, C. R.

    1985-01-01

    The 0.0175-scale thin-skin thermocouple Model 60-OTS was tested in the von Karman Gas Facility 40-inch continuous flow supersonic tunnel A and the VKF Tunnel C. Testing was conducted at Mach numbers 2.25 to 4.0, and Reynolds numbers from 0.4 x 10 to the 6th power/ft to 6.6 x 10 to the 6th power/ft. Angle of attack range was from -5.0 to +5.0 degrees, and angle of sideslip range was from -6 to +6 degrees. The primary objective of this test was to provide a valid base for the external tank (ET) and solid rocket booster (SRB) heating prediction methodology for ascent flight by taking heating data at Development Flight Instrumentation (DFI) locations for flight conditions simulating STS-1 through -4. A second objective was to obtain additional aeroheating data to support potential reduction of the thermal protection system (TPS) on the ET. The third phase of the test was funded and conducted by NASA/MSFC for the purpose of establishing confidence in the data base from the lower temperature tunnel A.

  5. Aerodynamic results of a separation effects test on a 0.01-scale model (52-OTS) of integrated SSV in the AEDC/VKF 40-by-40 inch supersonic wind tunnel A, volume 1

    NASA Technical Reports Server (NTRS)

    Campbell, J. H., II

    1975-01-01

    Experimental aerodynamic investigations were conducted, during the period July 18-19, 1974, in the AEDC/VKF Tunnel A facility on a 0.01-scale model (52-OTS) of the integrated space shuttle vehicle, including only one SRB. The purpose of the investigation was to obtain data for close-in proximity (SRB to orbiter/tank) effects with the orbiter/tank combination at relatively high alpha and beta attitudes, and with the SRB separation motors off. The AEDC Captive Trajectory System (CTS), which supported the SRB, was used in conjunction with the tunnel primary sector (supporting the orbiter/tank) to obtain grid type separation effects data. The one symmetrical SRB model was used interchangeably to obtain both right-hand and left-hand SRB data. Free-stream data were also obtained for the orbiter/tank and for the SRB. This data was used to provide baselines for proximity effects. The entire investigation was conducted at a free-stream Mach number of 4.5 with unit Reynolds number ranging from 4.0 to 6.5 million per foot.

  6. Place preferences associated with pups or cocaine change the expression of D2R, V1aR and OTR in the NAcc and MeA and the levels of plasma AVP, OT, T and E2 in mandarin vole fathers.

    PubMed

    Fang, Qianqian; Wang, Jianli

    2017-03-04

    Drug abuse often has negative impacts on parenting behavior. The dopamine (DA), arginine vasopressin (AVP) and oxytocin (OT) systems are involved in paternal behavior and drug-induced behaviors. Mandarin voles (Microtus mandarinus) are socially monogamous rodents with high levels of paternal behavior. The aims of this study were to examine the protein expression levels of the DA 2-type receptor (D2R), AVP receptor 1A(V1aR) and OT receptor (OTR) in the nucleus accumbens (NAcc) and medial amygdala (MeA) as well as the plasma hormone responses after mandarin vole fathers were conditioned with their pups or cocaine. Our experimental models are based on the conditioned place preference (CPP) paradigm. We observed CPP in response to either pup- or cocaine-associated cues in the mandarin vole fathers. Fathers that were conditioned to either pups or cocaine had a lower expression of D2R and V1aR in the NAcc than did controls. Fathers that were conditioned to pups had higher levels of OTR expression in the MeA and higher plasma levels of AVP, OT, estradiol (E2), and lower plasma levels of testosterone (T) than did controls. Fathers that were conditioned to cocaine exhibited lower levels of plasma AVP and T. These results indicate that the reward effects of pup and cocaine are both mediated by D2R, V1aR and OTR in the NAcc and MeA and that there are subtle differences between the pup and cocaine reward mechanisms that are associated with altered plasma AVP, OT, T and E2.

  7. A new report of Nocardiopsis valliformis strain OT1 from alkaline Lonar crater of India and its use in synthesis of silver nanoparticles with special reference to evaluation of antibacterial activity and cytotoxicity.

    PubMed

    Rathod, Dnyaneshwar; Golinska, Patrycja; Wypij, Magdalena; Dahm, Hanna; Rai, Mahendra

    2016-10-01

    The authors report the biological synthesis of silver nanoparticles (AgNPs) by alkaliphilic actinobacterium Nocardiopsis valliformis OT1 strain isolated for the first time from Lonar crater, India. The primary detection of silver NPs formation was made by colour change from colourless to dark brown and confirmed by UV-Vis spectrum of AgNPs at 423 nm, specific for AgNPs. Further, AgNPs were characterized by nanoparticle tracking analysis, Zeta sizer, Fourier transform infrared spectroscopy (FTIR) and transmission electron microscopy (TEM) analyses. FTIR analysis showed the presence of proteins as capping agent. TEM analysis revealed the formation of spherical and polydispersed AgNPs within the size range of 5-50 nm. The antimicrobial activity of silver nanoparticles against Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus and Bacillus subtilis was evaluated. The AgNPs showed the maximum antibacterial activity against B. subtilis (Gram positive) and the minimum against E. coli (Gram negative). The minimal inhibitory concentration values of AgNPs for the tested bacteria were found to be in the range of 30-80 µg/mL. The AgNPs demonstrated higher antibacterial activity against all the bacteria tested as compared with the commercially available antibiotics. The cytotoxicity of biosynthesized AgNPs against in vitro human cervical cancer cell line (HeLa) demonstrated a dose-response activity. The IC50 value was found to be 100 µg/mL of AgNPs against cancer HeLa cell line.

  8. Exploring Cultural Competence amongst OT Students

    PubMed Central

    Mpanza, December M.; Carey, Tarryn; Jiyane, Kwenzile; Andrews, Bicolé; Mashele, Sam

    2017-01-01

    Occupational therapy relies primarily on communication between the therapist and client for effective intervention. Adequate communication may be influenced by language and cultural differences between the therapist and client. Cultural competence in relation to language and culture is thus a vital part in practice. Limited research exists on cultural competence in occupational therapy students. This study thus aimed to explore the cultural competence of final year students and their perceptions of their own cultural competence, with respect to language and culture in their practice as students. An explorative qualitative study design was utilised with a nonprobability purposeful sample of 21 final year undergraduate students at a tertiary institute in South Africa. Three focus groups were conducted, comprising between 6 and 8 students in each group. Thematic analysis using inductive reasoning was undertaken in order to analyse the students' experiences and understanding of cultural competence. Findings of the study suggest that cultural competence, in relation to language and culture, influences the occupational therapy intervention process. It was shown to both positively and negatively influence intervention through supporting or hindering rapport building, client centeredness, and effective intervention.

  9. Results of a M = 5.3 heat transfer test of the integrated vehicle using phase-change paint techniques on the 0.0175-scale model 56-OTS in the NASA/Ames Research Center 3.5-foot hypersonic wind tunnel

    NASA Technical Reports Server (NTRS)

    Marroquin, J.

    1985-01-01

    An experimental investigation was performed in the NASA/Ames Research Center 3.5-foot Hypersonic Wind Tunnel to obtain supersonic heat-distribution data in areas between the orbiter and external tank using phase-change paint techniques. The tests used Novamide SSV Model 56-OTS in the first and second-stage ascent configurations. Data were obtained at a nominal Mach number of 5.3 and a Reynolds number per foot of 5 x 10 to the 6th power with angles of attack of 0 deg, +/- 5 deg, and sideslip angles of 0 deg and +/- 5 deg.

  10. Identity of Innovative Multifunctional Material Manufacturing Business in Latvia / Inovatīvu Daudzfunkcionālo Materiālu Ražotāju Identitāte Latvijā

    NASA Astrophysics Data System (ADS)

    Geipele, I.; Staube, T.; Ciemleja, G.; Zeltins, N.; Ekmanis, Yu.

    2015-08-01

    The publication comprises the results from the practical scientific investigation to define the profile and distinctions of the Latvian innovative multifunctional material manufacturing industry. The research is carried out by a holistic approach, including expert interviews, qualitative analysis of the official register data, practical survey, and financial data analysis. The paper seeks to give the detailed data on a technological profile of the mentioned representative companies, if there is a synergy or tough competition in the Latvian market. The current research is topical, because it is unique and does not have analogues in Latvia, and the research is timely due to correspondence with recently stated Research and Innovation Strategies for Smart Specialisation in Latvia. The main findings are associated with recognition of the factors that make impact on commercialisation of the finished goods, obtained financial results and planned directions of development of the respondent companies. Publikācija sniedz veiktā zinātniski praktiskā pētījuma rezultātus, kura ietvaros tika noteikts Latvijas inovatīvu daudzfunkcionālo materiālu ražotāju darbības profils un identitāte. Pētījumā tika izmantota kompleksās analīzes metode, kas ietvēra ekspertu intervijas, uzņēmumu oficiāli reģistrēto datu kvalitatīvo analīzi, zinātniski praktisko aptauju, kā arī pētāmo uzņēmumu finanšu darbības rezultātu analīzi. Zinātniskais darbs sniedz izsmeļošu informāciju par mērķa uzņēmumu tehnoloģisko profilu un pēta, vai Latvijas mērķa ražošanas nozarē ir sinerģijas vai sīvās konkurences pazīmes. Šim zinātniskajam pētījumam ir noteikta aktualitāte saskaņā ar tā unikalitāti Latvijas valsts mērogā un atbilstība Viedās specializācijas stratēģijai. Pētījuma galvenie secinājumi ir saistīti ar uzņēmumu produkcijas komercializācijas ietekmējošo faktoru apzināšanu, sasniegtajiem finansiālajiem rezultātiem un pl

  11. 12 CFR 555.310 - How do I notify OTS?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) Describe the transactional web site. (2) Indicate the date the transactional web site will become operational. (3) List a contact familiar with the deployment, operation, and security of the transactional web site. (b) Transition provision. If you established a transactional web site after the date of your...

  12. 12 CFR 555.310 - How do I notify OTS?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) Describe the transactional web site. (2) Indicate the date the transactional web site will become operational. (3) List a contact familiar with the deployment, operation, and security of the transactional web site. (b) Transition provision. If you established a transactional web site after the date of your last...

  13. Factors associated with IADL independence: implications for OT practice.

    PubMed

    Chen, Szu-Wei; Chippendale, Tracy

    2017-03-01

    Globally, the population is aging. Instrumental activities of daily living (IADL) are an important component of independent function and impact the ability of older adults to age in place. Therefore, factors associated with IADL independence warrant further study. To explore the association of age, depressive symptoms and leisure participation with IADL independence, and the relative importance of these three factors in predicting IADL independence. A cross-sectional design using an existing data set was employed. Older adults age 60 and older (n = 98) who resided in senior housing or their own home/apartment were included in the study. A hierarchical multiple regression analysis was employed. The second model predicting IADL independence using age, depressive symptoms and level of leisure participation was significant (F(3,96) = 15.57, p < 0.001) and explained 31.00% of the variance in IADL independence compared to the first regression model, which included age alone (R(2) adjusted = 18.00%). Age was the strongest of the three predictors, accounting for 11.40% of the variance in IADL independence. Depressive symptoms and participation in leisure activities were also significant predictors, their unique contributions being 7.30 and 4.30%, respectively. Age, depressive symptoms and leisure participation are all significant predictors of IADL independence among older adults. Therefore, according to our preliminary findings, leisure participation and non-pharmacological interventions for depressive symptoms warrant attention in practice in relation to IADL independence.

  14. 12 CFR 555.310 - How do I notify OTS?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) Describe the transactional web site. (2) Indicate the date the transactional web site will become operational. (3) List a contact familiar with the deployment, operation, and security of the transactional web site. (b) Transition provision. If you established a transactional web site after the date of your...

  15. 12 CFR 555.310 - How do I notify OTS?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) Describe the transactional web site. (2) Indicate the date the transactional web site will become operational. (3) List a contact familiar with the deployment, operation, and security of the transactional web site. (b) Transition provision. If you established a transactional web site after the date of your...

  16. OT2_baltieri_5: Star formation in proto-clusters

    NASA Astrophysics Data System (ADS)

    Altieri, B.

    2011-09-01

    Massive clusters of galaxies have been found to date from as early as 3-4 billion years after the Big Bang. Cosmological simulations using the current cold dark matter model predict that these systems should descend from 'proto-clusters' - early overdensities of massive galaxies that merge hierarchically to form a cluster. These protocluster regions themselves are built up hierarchically and so are expected to contain extremely massive galaxies, progenitors of the quiescent behemoths observed in cores of the present day massive galaxy clusters. Observational evidence for this picture, however, is sparse because high-redshift proto-clusters are rare and difficult to observe. Here we propose to probe with Herschel SPIRE the very beginning of the cluster and massive galaxies formation process by observing 5 proto-clusters at 3

  17. 12 CFR 574.7 - Determination by the OTS.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... of legal or supervisory issues; (C) The board of directors and executive officers of the holding... the association; (D) The acquisition raises no significant issues of law or policy under then current... frames: (1) On the business day prior to the date of consummation of the acquisition, the chief...

  18. 12 CFR 555.310 - How do I notify OTS?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) Describe the transactional web site. (2) Indicate the date the transactional web site will become operational. (3) List a contact familiar with the deployment, operation, and security of the transactional web site. (b) Transition provision. If you established a transactional web site after the date of your last...

  19. NYPIRG Petion to Object ot Kings Plaza Title V Permit

    EPA Pesticide Factsheets

    This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Petition Database available at www2.epa.gov/title-v-operating-permits/title-v-petition-database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  20. 12 CFR 574.7 - Determination by the OTS.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... company by such savings association, and related applications for permission to organize an interim..., which involve: (A) Fraud, moral turpitude, dishonesty, breach of trust or fiduciary duties, organized crime or racketeering; (B) Violation of securities or commodities laws or regulations; (C) Violation of...

  1. 12 CFR 574.7 - Determination by the OTS.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... company by such savings association, and related applications for permission to organize an interim..., which involve: (A) Fraud, moral turpitude, dishonesty, breach of trust or fiduciary duties, organized crime or racketeering; (B) Violation of securities or commodities laws or regulations; (C) Violation of...

  2. 12 CFR 574.7 - Determination by the OTS.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... company by such savings association, and related applications for permission to organize an interim..., which involve: (A) Fraud, moral turpitude, dishonesty, breach of trust or fiduciary duties, organized crime or racketeering; (B) Violation of securities or commodities laws or regulations; (C) Violation of...

  3. Complete genome sequence of Haliscomenobacter hydrossis type strain (OT)

    SciTech Connect

    Daligault, Hajnalka E.; Lapidus, Alla L.; Zeytun, Ahmet; Nolan, Matt; Lucas, Susan; Glavina Del Rio, Tijana; Tice, Hope; Cheng, Jan-Fang; Tapia, Roxanne; Han, Cliff; Goodwin, Lynne A.; Pitluck, Sam; Liolios, Konstantinos; Pagani, Ioanna; Ivanova, N; Huntemann, Marcel; Mavromatis, K; Mikhailova, Natalia; Pati, Amrita; Chen, Amy; Palaniappan, Krishna; Land, Miriam L; Hauser, Loren John; Brambilla, Evelyne-Marie; Rohde, Manfred; Verbarg, Susanne; Goker, Markus; Bristow, James; Eisen, Jonathan; Markowitz, Victor; Hugenholtz, Philip; Kyrpides, Nikos C; Klenk, Hans-Peter; Woyke, Tanja

    2011-01-01

    Haliscomenobacter hydrossis van Veen et al. 1973 is the type species of the genus Halisco- menobacter, which belongs to order 'Sphingobacteriales'. The species is of interest because of its isolated phylogenetic location in the tree of life, especially the so far genomically un- charted part of it, and because the organism grows in a thin, hardly visible hyaline sheath. Members of the species were isolated from fresh water of lakes and from ditch water. The genome of H. hydrossis is the first completed genome sequence reported from a member of the family 'Saprospiraceae'. The 8,771,651 bp long genome with its three plasmids of 92 kbp, 144 kbp and 164 kbp length contains 6,848 protein-coding and 60 RNA genes, and is a part of the Genomic Encyclopedia of Bacteria and Archaea project.

  4. OT1_atielens_1: Physical conditions in PDRs

    NASA Astrophysics Data System (ADS)

    Tielens, A.

    2010-07-01

    Luminous stars have a profound influence on their environment as their far-UV (6-13.6 eV) photons dissociate and ionize surrounding gas. The gas in these so-called PhotoDissociation Regions (PDRs) is heated by the photo-electric effect on polycyclic aromatic hydrocarbon (PAH) molecules and very small grains (VSG) and cools through emission in atomic fine-structure ([OI], [CII], [SiII]) and molecular rotational (H2, CO) lines. PDR models are known to have intrinsic problems and have moreover only been tested using observations with very large beams on complex regions. Herschels high sensitivity, high spatial resolution, and wide wavelength coverage allows for the first time a study of the far-IR spectra of spatially resolved PDRs. We propose to map the key diagnostic, far-IR and sub-mm, atomic ([CII] 158m, [OI] 63, 145m) and molecular (CO) lines using PACS and SPIRE in a sample of edge-on, spatially resolved Galactic PDRs. The sources in this sample are all well-studied over a wide-wavelength range and have all been mapped by IRS/Spitzer in the rotational H2 lines, the [SiII] 34m line, the PAH features and the VSG continuum. The goals of our combined Herschel/Spitzer study are to determine the density and temperature structure of the region, to quantify the gas energetics (cooling/heating efficiency), and to compare the gas (heating) characteristics with the emission characteristics of the (neutral & cationic) PAHs and VSGs. This will provide deep insight in the photo-electric heating of atomic gas which is central to the structure of PDRs, the phases of the ISM, and the structure of protoplanetary disks. In addition, these well-known Galactic PDRs provide natural laboratories for studies of the interaction of massive stars with their environment and a semi-empirical way of calibrating the infrared characteristics of regions of massive star formation and, thus, the observational characteristics of galaxies out to the early Universe.

  5. OT1_dhunter_3: Characterizing Molecular Clouds at Low Metallicity

    NASA Astrophysics Data System (ADS)

    Hunter, D.

    2010-07-01

    Molecular gas is difficult to detect from traditional millimeter CO transitions in dwarf galaxies below a certain metallicity. Yet, there is evidence for lots of molecular H_2 in these galaxies. Fortunately, Photo-dissociation Regions are a better tracer of the molecular material in low metallicity systems. In metal-poor galaxies, PDRs dominate the molecular core where CO is found, and in the current paradigm the PDR grows and the core shrinks as metallicity decreases. Thus, we expect critical differences in the molecular clouds of dwarfs compared to spirals, with the differences becoming more extreme with lower metallicity. Yet, understanding these differences and their consequences to star formation is essential to understanding the processes that drive star formation at low metallicities. Therefore, we propose to observe the PDRs in 5 regions in 5 typical metal-poor dwarf galaxies spanning a range in oxygen abundance. We will use these observations to characterize the molecular gas, examine the correspondence between the molecular clouds and the atomic gas and star formation characteristics, and determine the characteristics of the atomic ISM that are necessary for the formation of these dense molecular clouds. We will also test the molecular cloud structure paradigm as a function of metallicity.

  6. "Other Transactions" (OT) Guide for Prototype Projects

    DTIC Science & Technology

    2000-12-21

    able to make its required investment. Such other transactions should address the procedures for verifying cost share contributions, the conditions...Section 845 Other Transactions (Report Control Symbol DD-A&T(AR)2037)," October 16, 1997. 3) USD(AT&L)/DDP memorandum, "Financial and Cost Aspects...total cost of the prototype project is to be paid out of funds provided by the parties to the transaction other than the federal government. (ii

  7. OT1_mrubio_1: Clumping in OB-star winds

    NASA Astrophysics Data System (ADS)

    Rubio, M.

    2010-07-01

    Massive stars, their nature and evolution, play a important role at all stages of the Universe. Through their radiatively driven winds they influence on the dynamics and energetics of the interstellar medium. The winds of OB stars are the most studied case. Commonly, the mass-loss rates of luminous OB stars are inferred from several types of measurements, the strengths of UV P Cygni lines, H-alpha emission and radio and FIR continuum emission. Recent evidence indicates that currently accepted mass-loss rates may need to be revised downwards when small-scale density inhomogeneities (clumping) are taken into account. We argue that only a consistent treatment of ALL possible diagnostics, scanning different parts of the winds, and analyzed by means of state of the art model atmospheres, will permit the determination of true mass-loss rates. To this end we have assembled a variety of multi-wavelength data, but one crucial observational set is missing: far-IR diagnostics of free-free emission, which uniquely constrain the clumping properties of the wind at intermediate heights. We propose, therefore, to use PACS photometric mode to fill this crucial gap, studying the 70 and 110 micron fluxes of a carefully selected sample of 29 O4-B8 stars. These observations will provide the missing information to derive the clumping properties of the entire outflow, to understand the wind physics, and to obtain reliable massloss rates.

  8. OT2_mrubio_2: Clumping in OB-star winds

    NASA Astrophysics Data System (ADS)

    Rubio, M.

    2011-09-01

    Massive stars, their nature and evolution, play a important role at all stages of the Universe. Through their radiatively driven winds they influence on the dynamics and energetics of the interstellar medium. The winds of OB stars are the most studied case. Commonly, the mass-loss rates of luminous OB stars are inferred from several types of measurements, the strengths of UV P Cygni lines, H-alpha emission and radio and FIR continuum emission. Recent evidence indicates that currently accepted mass-loss rates may need to be revised downwards when small-scale density inhomogeneities (clumping) are taken into account. We argue that only a consistent treatment of ALL possible diagnostics, scanning different parts of the winds, and analyzed by means of state of the art model atmospheres, will permit the determination of true mass-loss rates. To this end we have assembled a variety of multi-wavelength data, but one crucial observational set is missing: far-IR diagnostics of free-free emission, which uniquely constrain the clumping properties of the wind at intermediate heights. We propose, therefore, to use PACS photometric mode to fill this crucial gap, studying the 70 and 110 micron fluxes of a carefully selected sample of 29 O4-B8 stars. These observations will provide the missing information to derive the clumping properties of the entire outflow, to understand the wind physics, and to obtain reliable massloss rates.

  9. Treatability study Number PDC-1-O-T. Final report

    SciTech Connect

    1998-04-22

    Los Alamos National Laboratory provided treatability study samples from four waste streams, designated Stream {number_sign}1, Stream {number_sign}3, Stream {number_sign}6, and Stream {number_sign}7. Stream {number_sign}1 consisted of one 55-gallon drum of personal protective equipment (PPE), rags, and neutralizing agent (bicarbonate) generated during the cleanup of a sodium dichromate solution spill. Stream {number_sign}3 was one 55-gallon drum of paper, rags, lab utensils, tools, and tape from the decontamination of a glovebox. The sample of Stream {number_sign}6 was packaged in three 30-gallon drums and a 100 ft{sup 3} wooden box. It consisted of plastic sheeting, PPE, and paper generated from the cleanup of mock explosive (barium nitrate) from depleted uranium parts. Stream {number_sign}7 was scrap metal (copper, stainless and carbon steel joined with silver solder) from the disassembly of gas manifolds. The objective of the treatability study is to determine: (1) whether the Perma-Fix stabilization/solidification process can treat the waste sample to meet Land Disposal Restrictions and the Waste Acceptance Criteria for LANL Technical Area 54, Area G, and (2) optimum loading and resulting weight and volume of finished waste form. The stabilized waste was mixed into grout that had been poured into a lined drum. After each original container of waste was processed, the liner was closed and a new liner was placed in the same drum on top of the previous closed liner. This allowed an overall reduction in waste volume but kept waste segregated to minimize the amount of rework in case analytical results indicated any batch did not meet treatment standards. Samples of treated waste from each waste stream were analyzed by Perma-Fix Analytical Services to get a preliminary approximation of TCLP metals. Splits of these samples were sent to American Environmental Network`s mixed waste analytical lab in Cary, NC for confirmation analysis. Results were all below applicable limits.

  10. 12 CFR 510.5 - Release of unpublished OTS information.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... their official capacities. Examples of unpublished information include: (i) Information in the memory of... demonstrating that the information is highly relevant, the requester must explain in detail how the requested...

  11. OT1_swampfle_1: WATCH - WATer Chemistry with Herschel

    NASA Astrophysics Data System (ADS)

    Wampfler, S.

    2010-07-01

    Water is one of the most abundant species in star-forming regions and plays important roles in both the energy balance, acting as a coolant, and the chemistry of star formation. Many of the species involved in the water chemistry emit in the far-infrared and are thus not observable from ground based facilities because of atmospheric absorption. Therefore, the Herschel Space Observatory provides a unique opportunity to study the chemical reactions involved in the formation and destruction of water and to probe the energetic processes in star-forming regions. Previous results from Herschel have shown that two species, OH+ and H2O+, that were thought to be important in the water chemistry of young stellar objects, are now mainly attributed to foreground clouds. These results raised the question on which chemical paths the formation and destruction of water takes place in the interior of protostellar envelopes. In this proposal, we plan to observe the different formation and destruction routes of water in a sample of eight nearby young stellar objects, which were chosen to cover a broad range of masses, luminosities and evolutionary stages. We propose to observe H3O+ and HCO+, two species that are closely linked to the formation and destruction of H2O and require high temperatures for excitation, in serveral high-J lines. This effort is complementary to the observations of H2O and OH done in the 'Water in star-forming regions with Herschel (WISH)' key project. The combination of the information from the H2O, OH, H3O+ and HCO+ emission will tell us on which routes the formation and destruction of H2O in protostellar envelopes proceeds.

  12. OTS cash disbursement process for HANDI 2000 business management system

    SciTech Connect

    Wilson, D.

    1998-08-24

    Payments by check are disbursed either through the payroll system or the Accounts Payable Master. Payments to persons with a valid employee number are processed through the payroll system. Payments to persons without valid employee number are processed through APM.

  13. Report: Ozone Transport Commission Incurred Costs Under EPA Assistance Agreements XA98379901, OT83098301, XA97318101, and OT83264901

    EPA Pesticide Factsheets

    Report #2007-4-00068, July 31, 2007. We questioned $2,723,706 of the $9,042,706 in reported outlays because the recipient claimed unallowable outlays for contractual services, indirect costs, and in-kind costs.

  14. (/sup 3/H)-(Thr4,Gly7)OT: a highly selective ligand for central and peripheral OT receptors

    SciTech Connect

    Elands, J.; Barberis, C.; Jard, S.

    1988-01-01

    Oxytocin receptors in rat hippocampal synaptic plasma membranes were compared with mammary gland and uterine oxytocin receptors. For this purpose, a highly specific oxytocic agonist (Thr4,Gly7)oxytocin was tritiated. We demonstrated that this ligand labels oxytocin receptors selectively. Scatchard analyses revealed a high affinity for all the oxytocin receptors investigated, with equilibrium dissociation constants between 1.0 and 2.0 nM. Binding appeared to take place at a single population of receptor sites. Competition experiments confirmed the high affinity of arginine vasopressin for hippocampal oxytocin receptors but also revealed that mammary gland and uterine oxytocin receptors do not discriminate more efficiently between oxytocin and arginine vasopressin. This lack in specificity is not affected by applying different concentrations of Mg ions.

  15. VHF Direction Finder (VDF) Operational Test and Evaluation (OT&E) integration and OT&E Operational Test Report

    DTIC Science & Technology

    1994-05-01

    conducted at three locations on several dates. Testing took place at the FAA Technical Center and the Millville , NJ , AFSS in 1988. Additional testing...lnternational Airport NJ .08405. Thim: dzuzen? ha! Deon capprov~d f 31 p.b1ic rdease and sale: its dia tributiod n b UfiLn t.ed I DTIC QUAL 1Ty I.WJSP pCrEC...U.S. Department of Transportation FederalAviation Administration Technical CenterAtlantic CityAirport, NJ 08405 4V " 1 099 NOTICE This document Is

  16. Dimolybdenum(III) complexes of -OSi(OtBu)3, -O2P(OtBu)2 and-OB[OSi(OtBu)3]2 as single-source molecular precursors tomolybdenum-containing, multicomponent oxide materials

    SciTech Connect

    Fujdala, Kyle L.; Tilley, T. Don

    2004-01-15

    The following dimolybdenum complexes containing -OSi(O{sup t}Bu){sub 3}, -O{sub 2}P(O{sup t}Bu){sub 2}, and -OB[OSi(O{sup t}Bu){sub 3}]{sub 2} ligands have been synthesized and structurally characterized: Mo{sub 2}(NMe{sub 2}){sub 4}[OSi(O{sup t}Bu){sub 3}]{sub 2} (1), Mo{sub 2}(O{sup t}Bu)4[OSi(O{sup t}Bu){sub 3}]{sub 2} (2), Mo{sub 2}(NMe){sub 4}(OB[OSi(O{sup t}Bu){sub 3}]{sub 2}){sub 2} (3), Mo{sub 2}(NMe{sub 2}){sub 2}[-O{sub 2}P(O{sup t}Bu){sub 2}]{sub 2}[O{sub 2}P(O{sup t}Bu){sub 2}]{sub 2} (4), Mo{sub 2}(NMe{sub 2}){sub 2}[OSi(O{sup t}Bu){sub 3}]{sub 2}[-O{sub 2}P(O{sup t}Bu){sub 2}]{sub 2} (5), and Mo{sub 2}(NMe{sub 2}){sub 2}[-O{sub 2}P(O{sup t}Bu){sub 2}]{sub 2}OB[OSi(O{sup t}Bu){sub 3}]{sub 2} (6). The isolation and structural characterization of trans- and cis-isomers of complexes 4 and 5 (4a and 4b, 5a and 5b, respectively) are also reported. Studies of the thermal decompositions of the complexes (by thermogravimetric analysis and solution 1H NMR spectroscopy) were performed. Xerogels with approximate compositions of 2MoO{sub 1.5}{center_dot}2P{sub 2}O{sub 5} and 2MoO{sub 1.5}{center_dot}2P{sub 2}O{sub 5}{center_dot}2SiO{sub 2} were derived from 4a and 5a or 5b, respectively, via solution thermolyses (toluene). The as-synthesized (and dried) xerogels contain one equiv of HNMe{sub 2} per molybdenum center (by combustion analysis, IR spectroscopy, and thermogravimetric analysis), and these materials have high surface areas (up to 270 m{sup 2} g{sup -1}). Upon calcination at 300 C, the coordinated amines are lost and the surface areas are significantly reduced (to 40 m{sup 2} g{sup -1} and <5 m{sup 2} g{sup -1} for the materials derived from 4 and 5a or 5b, respectively). Solid-state {sup 31}P MAS NMR spectroscopy suggests that the as-synthesized xerogels retain structural features of the starting molecular precursors, as indicated by the presence of resonances that correspond to both bridging and terminal -O{sub 2}P(O{sup t}Bu){sub 2} ligands. Upon calcination at 300 C, the resonances for bridging -O{sub 2}P(O{sup t}Bu){sub 2} groups are replaced by those for PO{sub 4}{sup 3-}. The material derived from 4 exhibits low activity and poor selectivity for the oxidative dehydrogenation (ODH) of propane to propylene. Cothermolyses of 4 and Bi[OSi(O{sup t}Bu){sub 3}]{sub 3} resulted in formation of Bi/Mo/P/Si/O materials with improved performance for the ODH of propane.

  17. 78 FR 54403 - Removal of Transferred OTS Regulations Regarding Recordkeeping and Confirmation Requirements for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-04

    ... insured banks and foreign banks having an insured branch. The FDIC proposes to amend the definition... under similar statutory terminology. Section 312(c) of the Dodd-Frank Act amended the definition of... to amend section 344.3 of part 344 to remove the definition of ``bank'' and add the definition of...

  18. Experimental Validation of OT Solutions to the Comprehension-Production Dilemma

    ERIC Educational Resources Information Center

    Gierut, Judith A.

    2006-01-01

    The relationship between perception and production remains an unresolved issue within the study of phonological acquisition. Recent developments in optimality theory offer potentially new solutions to this long-standing problem; but thus far, the proposals that have been advanced are in the absence of actual perception-production data from a given…

  19. 78 FR 54401 - Removal of Transferred OTS Regulations Regarding Post-Employment Activities of Senior Examiners

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-04

    ... implemented section 6303(b) of the Intelligence Reform and Terrorism Prevention Act of 2004.\\4\\ This Act added... later than November 4, 2013. IV. Regulatory Analysis and Procedure A. The Paperwork Reduction Act The... analysis of the rule and publish the analysis for comment. Twelve CFR part 336, subpart C was issued as...

  20. Increased radiosensitivity of a subpopulation ot T-lymphocyte progenitors from patients with Fanconi's anemia

    SciTech Connect

    Knox, S.J.; Wilson, F.D.; Greenberg, B.R.; Shifrine, M.; Rosenblatt, L.S.; Reeves, J.D.; Misra, H.

    1981-06-01

    In vitro radiation survival of peripheral blood T lymphocytes was studied in 15 clinically normal adults and 4 patients with Fanconi's anemia. Tritiated thymidine incorporation in a whole blood lymphocyte stimulation test (LST) and a newly developed whole blood T-lymphocyte colony assay were used to measure lymphocyte blastogenesis and colony formation in response to phytohemagglutinin (PHA) or concanavalin-A (Con-A) stimulation. Lymphocyte colony formation was found to be consistently more sensitive than the LST for detection of low-level radiation effects using both normal cells and lymphocytes from Fanconi's anemia patients. Lymphocytes from patients with Fanconi's anemia were significantly more sensitive to in vitro x-irradiation than lymphocytes from clinically normal individuals as measured by their ability to divide when stimulated by PHA in the LST (patients, D37 . 198 R; normals, D37 . 309 R, p . 0.057) and colony formation assay (patients, D37 . 53 R; normals, D37 . 109 R, p . 0.016). No significant difference in the radiosensitivity of the Con-A response was observed between the two groups. The PHA-responsive T-lymphocyte subpopulation in Fanconi's anemia patients appears to be intrinsically defective. The nature of this defect, significance in the disease process, and relevancy of these findings to the establishment of radiation protection standards are discussed.

  1. OT1_shaileyd_1: Testing the XDR/High-J CO Paradigm in Nearby Galaxies

    NASA Astrophysics Data System (ADS)

    Hailey-Dunsheath, S.

    2010-07-01

    One of the most exciting first results from SPIRE and PACS spectroscopy is the detection of high-J CO emission in galaxies. Such emission has long been proposed as a tracer of X-ray dominated regions (XDRs) produced by AGN, and as a powerful diagnostic tool for future millimeter-wave study of AGN at high redshift. The shortest wavelength submillimeter CO lines detected by SPIRE-FTS in the X-ray luminous ULIRG Mrk 231 are interpreted as arising from an extended XDR, providing strong observational support for the XDR/high-J CO connection. However, our group (SHINING; PI E. Sturm) has used PACS to detect even higher-J far-IR CO emission in a few nearby galaxies, including 2 starburst galaxies with little evidence of a luminous AGN. Can high-J CO emission also be produced in gas heated by the UV radiation or mechanical output of a starburst? To address this question we propose to measure a set of far-IR CO lines in 4 nearby AGN and 4 starburst galaxies, as well as in 2 merging systems with large masses of shock-heated molecular gas. Does the high-J CO line SED reflect the different excitation mechanisms in these template objects? We additionally propose to use OH line observations to estimate the abundance of this molecule, which is a sensitive tracer of X-ray-driven chemistry. The OH line profiles will also be used to search for evidence of molecular outflows, which may drive shock heating. Each of these galaxies will have SHINING GT observations of the set of far-IR fine-structure lines, which includes important tracers of UV-, X-ray-, and shock-heated gas. The AGN subsample is restricted to the most nearby systems, where the high spatial resolution of PACS is sufficient to separate the nuclear AGN-heated gas from the circumnuclear star-forming regions. The PACS CO data obtained here will provide the first well-sampled far-IR extragalactic CO line SEDs, and will be an essential reference for future high redshift studies.

  2. OT2_mcordine_2: Revealing the nature of the remarkable object IRAS 19312+1950

    NASA Astrophysics Data System (ADS)

    Cordiner, M.

    2011-09-01

    The IRAS source 19312+1950 is a peculiar bipolar nebula that has eluded firm characterisation since its discovery. It exhibits maser and outflow properties similar to a massive O-rich AGB star, but shows molecular species such as CH3OH and HC3N that are more typically found in molecular clouds or YSOs. The source is surrounded by remarkable NIR nebulosity and has an unusual SED. The puzzle over the true nature of this object is confounded by our Spitzer IR spectrum that shows amorphous silicates and CO2 ice, but also emission from what may be crystalline silicates. In order to understand the physical properties of the gas and dust in the vicinity of IRAS 19312+1950, we propose to perform Herschel observations of emission from CO and H2O across a broad wavelength range from sub-mm to IR. Observations of transitions from a variety of energy levels will allow us to probe different temperature and density regimes within the source, from which we will construct a picture of its physical structure through radiative transfer/excitation modelling. HIFI observations will allow us to separate the broad and narrow molecular line components and PACS IFU mapping will provide crucial spatial information on the physical structure of the source. We also propose to perform a PACS SED scan to better characterise the source SED, and measure diagnostic spectral features of the dust and gas such as the forsterite 69 micron band, the OI 63 micron line and the N II 122 and 205 micron lines. The combination of these unique observations will help solve the puzzle of the nature of this peculiar object.

  3. OT1_philybla_1: The chemistry of nitrogen in dark clouds

    NASA Astrophysics Data System (ADS)

    Hily-Blant, P.

    2010-07-01

    Nitrogen is the fifth most abundant element in the local Universe. It is essential component of molecules associated to Earth-type life. Yet, the reservoir of nitrogen in the dense ISM, where stars, and ultimately planets, form, is not known. This is for good reasons. The main reservoir of gas-phase nitrogen are expected to be N or N2, and it is likely that most of the nitrogen be indeed frozen-out on dust grains in the form of ammonia ices. However, N and N2 are not observable in the shielded environments characterizing the embryos of star-forming regions. Hence, all what is know about nitrogen must rely on indirect observations of N-bearing molecules, the lightest (and thus among the easiest to form) of which are hardly detectable from the ground. To date, and despite longstanding efforts, our comprehension of the chemistry of nitrogen remains elusive. The HSO/HIFI instrument is opening new avenues in this respect, allowing astronomers to readily detect nitrogen hydrides and several key species of the nitrogen chemistry. This is the aim of this proposal. We propose the observation of key species that are observable only with Herschel. Those include NH, NH2 and NH3 (in their ortho and para forms), as well as their deuterated isotopologues, and other pivotal species like CH and CH2. This corpus of observations in order will allow to assess our understanding of the chemistry of nitrogen in dark cloud conditions, and answer the fundamental and open question, whether dust processes are necessary catalysts in this chemistry.

  4. The Transition from Spacecraft Development Ot Flight Operation: Human Factor Considerations

    NASA Technical Reports Server (NTRS)

    Basilio, Ralph R.

    2000-01-01

    In the field of aeronautics and astronautics, a paradigm shift has been witnessed by those in academia, research and development, and private industry. Long development life cycles and the budgets to support such programs and projects has given way to aggressive task schedules and leaner resources to draw from all the while challenging assigned individuals to create and produce improved products of processes. however, this "faster, better, cheaper" concept cannot merely be applied to the design, development, and test of complex systems such as earth-orbiting of interplanetary robotic spacecraft. Full advantage is not possible without due consideration and application to mission operations planning and flight operations, Equally as important as the flight system, the mission operations system consisting of qualified personnel, ground hardware and software tools, and verified and validated operational processes, should also be regarded as a complex system requiring personnel to draw upon formal education, training, related experiences, and heuristic reasoning in engineering an effective and efficient system. Unquestionably, qualified personnel are the most important elements of a mission operations system. This paper examines the experiences of the Deep Space I Project, the first in a series of new technology in-flight validation missions sponsored by the United States National Aeronautics and Space Administration (NASA), specifically, in developing a subsystems analysis and technology validation team comprised of former spacecraft development personnel. Human factor considerations are investigated from initial concept/vision formulation; through operational process development; personnel test and training; to initial uplink product development and test support. Emphasis has been placed on challenges and applied or recommended solutions, so as to provide opportunities for future programs and projects to address and disposition potential issues and concerns as early as possible to reap the benefits associated with learning from other's past experiences.

  5. Independent Evaluation Plan for Radiac Set AN/VDR-1() Operational Test IIA (OT IIA)

    DTIC Science & Technology

    1980-02-01

    Target Acquisition Laboratory, ATTN: DELCS-K (Mr. Leonard), Ft Monmouth, NJ 07703 Director, Academy of Health Sciencies , ATTN: HSA-CDM, Ft Sam Houston, TX...the system during vehicular radiological surveys. 2.1.5.1.2 Proximity while seated in terms of a human factor assessment of his ability to reach the

  6. ICT and OTs: a model of information and communication technology acceptance and utilisation by occupational therapists.

    PubMed

    Schaper, Louise K; Pervan, Graham P

    2007-06-01

    There is evidence to suggest that health professionals are reluctant to accept and utilise information and communication technologies (ICT) and concern is growing within health informatics research that this is contributing to the lag in adoption and utilisation of ICT across the health sector. Technology acceptance research within the field of information systems has been limited in its application to health and there is a concurrent need to develop and gain empirical support for models of technology acceptance within health and to examine acceptance and utilisation issues amongst health professionals to improve the success of information system implementation in this arena. This paper outlines a project that examines ICT acceptance and utilisation by Australian occupational therapists. It describes the theoretical basis behind the development of a research model and the methodology being employed to empirically validate the model using substantial quantitative, qualitative and longitudinal data. Preliminary results from Phase II of the study are presented. The theoretical significance of this work is that it uses a thoroughly constructed research model, with potentially the largest sample size ever tested, to extend technology acceptance research into the health sector.

  7. 78 FR 76768 - Removal of Transferred OTS Regulations Regarding Disclosure and Reporting of CRA-Related...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-19

    ... or Indian tribal law (including the Department of Hawaiian Home Lands), or a department, agency, or... rescind and remove a regulation entitled ``Disclosure and Reporting of CRA-Related Agreements.'' This....fdic.gov/regulations/laws/federal/propose.html . Follow instructions for submitting comments on...

  8. Bulgarski ezik za dobrovoltsi ot Korpusa na mira (Bulgarian Language for Peace Corps Volunteers. Bulgaria).

    ERIC Educational Resources Information Center

    Dimitrova, Aneta; Tomova, Christina; Tasseva, Mila

    This workbook and class guide for basic-to-intermediate Bulgarian provides a communicative orientation to the language. With its emphasis on social situations and everyday language, the book includes vocabulary, dialogs, discussion topics, and cultural-historical background information about Bulgaria. (CNP)

  9. Bulgarski ezik za dobrovoltsi ot Korpusa na mira (Bulgarian Language for Peace Corps Volunteers. Bulgaria).

    ERIC Educational Resources Information Center

    Dimitrova, Aneta; Tomova, Christina; Tasseva, Mila

    Designed for continued language learning beyond the intermediate level, this workbook provides practice and sets of exercises for improving speaking and listening skills in Bulgarian through class participation and discussion, and reading and writing. The book includes grammar explanations, news reports, brief biographies of prominent Bulgarians,…

  10. Position Location Reporting System (PLRS) OT (Operational Test) II Human Factors and Training Evaluation

    DTIC Science & Technology

    1984-07-01

    W (U4 oC) .- 4 0 { 0.. L. CC E I. isla ad ontolSttin 0 0 0U 0 0 4) J :3000 C~ > . 0 U LLO 00 0 5. V V.00 ( 02 0( X 1. Display and Control Station 5 0...0 0 0 24 4. Install/replace User Readout ( URO ) (applies only to manpack, surface vehicle, and auxiliary ground unit operators). 16 17 5 0 0 4 42...Replace manpack unit support 0-o equipment, such as sling, field > > . pack, pack frame or URO holder 0 W L q . 0 (applies only to manpack unit C

  11. OT1_jchiar_1: EPICS: Evolution of Protostellar Ices, Carbonates and Silicates

    NASA Astrophysics Data System (ADS)

    Chiar, J.

    2010-07-01

    Dynamical and energetic processes that occur during the evolution of a protostar have a strong influence on composition and other characteristics of the dust and these can be well probed with far-IR spectroscopy using Herschel's PACS instrument. Physical evolution of protostars, driven by gravity, is accompanied by a dramatic evolution of the dust, driven by condensation and coagulation, thermal processing by the central star, and shocks driven by protostellar jets. Mid-IR spectroscopic studies of dust in protostellar environments reveal a wide diversity of dust components ranging from volatile ices, to carbonates to refractory crystalline silicates. However, the relationship between the dust evolution and the evolution of the protostar itself has not yet been studied. The evidence suggests that ices are connected to the deepest embedded phase, while crystalline silicates may trace the presence of disks. Carbonates may be either connected to processing of ices in the envelope of YSOs or result from disk processes. In order to probe this dust evolution that accompanies protostellar evolution, we have carefully selected a sample of well-characterized protostars spanning a wide range in evolutionary age and protostellar characteristics from the deeply embedded class 0 stage through the accretion disk (class I) and protoplanetary disk (class II) phases. We will employ PACS in SED mode to study the lattice vibration phonon modes of the ices, silicates and carbonates that occur in the 51 to 220 micron region. Our proposed study will allow us to address at what stage of protostellar evolution different dust signatures become apparent. In this way, we can address the (inter)relationship of these different compounds and the processes involved in their formation. Our study directly addresses Herschel's top-level goal of studying the ingredients in the dust throughout the evolution of a protostar that will then become part of the planetesimal and planet-forming process.

  12. Seedling response of four birch species ot simulate nitrogen deposition: Ammonium vs. Nitrate

    SciTech Connect

    Crabtree, R.C; Bazzaz, F.A. )

    1993-05-01

    Chronic nitrogen deposition, from air pollution with high concentrations of nitrogen, has the potential to alter seedling shade tolerance and growth in the temperate forest of northeastern United States, by affecting both the form and the quantity of available nitrogen. Simulated deposition treatments were applied to seedling of four birch species that co-occur at Harvard Forest (Betula lenta, B. alleghaniensis, B. populifolia, and B. papyrifera). Seedlings were individually potted in forest soil, and grown under light treatment representative of forest understory and treefall gap light levels. In a split-plot design, N was applied at 25 and 50 kg[center dot]ha[sup [minus]1][center dot]yr[sup [minus]1], as either nitrate, ammonium nitrate, or ammonium, within each light environment. While B, populifolia and B. papyrifera, and B. lenta all showed increased biomass allocation to leaves added, and this response was conditional on rate of N application and light environment. At low light, nitrate-fed B. lenta grew best, and also at low rate of supply, nitrate treatments out-performed ammonium treatment. Greater growth under these conditions is probably the result of higher biomass allocation to leaves, and greater specific leaf area, which increased the leaf area ratio, and improved the capacity for carbon gain. Under N deposition regimes that increase soil nitrate availability, the differences in response of B. lenta and B. alleghaniensis of nitrate at low light may potentially lead to changes in the species composition of the seedling communities in the understory. When a treefall occurs, a different species mix of seedling will be released, with potential consequences for sapling and tree species mix. 31 refs., 2 figs., 4 tabs.

  13. I Have Students with Physical and Motor Problems: How Can an APE, OT, or PT Help?

    ERIC Educational Resources Information Center

    Silliman-French, Lisa; Candler, Catherine; French, Ron; Hamilton, Merry Lynne

    2007-01-01

    Majority of students with mental and/or motor impairments are frequently placed in general physical education classes. However, these students often are unable to attain the expected outcomes in these general settings. Based on the experience of the authors, general physical educators often attempt to modify their goals, objectives, teaching…

  14. OT1_jberna01_1: Characterising the Environment of Fullerene Formation

    NASA Astrophysics Data System (ADS)

    Bernard-Salas, J.

    2010-07-01

    The bulk of the dust that is injected into the interstellar medium is formed via a complex chemistry in AGB circumstellar environments, which transforms the atomic gas into molecules and dust. To date, more than 60 individual molecular species of both inorganic and organic nature and a handful of dust minerals have been identified in these outflows. These environments are also thought to be the birthplace for large aromatic species such as polycyclic aromatic hydrocarbons and fullerenes. Because of their remarkable stability, fullerenes have been predicted to survive the harsh conditions of the insterstellar medium. However, targeted searches for the presence of fullerenes in various astrophysical environments were unsuccessful or not conclusive, until now. The Spitzer mid-IR spectrum of Tc1, a young planetary nebula with a low excitation central star and a high C/O abundance ratio, shows clear traces of C60 and C70. This indicates that when conditions are favorable, fullerenes are formed in large quantities. The mid-IR spectra allow us to quantify the abundance of carbon in the fullerenes, estimate their temperature, and detect them in the solid state in circumstellar environments, but to date we have little information on the circumstellar dust or the composition of the gas. We propose to use the far-IR spectrum of Tc1 using the Herschel PACS spectrometer to study the energy balance and characterize the conditions in the circumstellar regions where fullerenes are formed.

  15. The Acquisition of English Lexical Stress by Chinese-Speaking Learners: An OT Account

    ERIC Educational Resources Information Center

    Yuan, Man; Cheng, Wei

    2017-01-01

    Lexical stress is an important contributor to foreign accent as well as intelligibility of second language (L2) speech. The present study intends to find out to what extent Chinese-speaking learners whose native language has less evident stress can acquire English lexical stress. A production test was administered to nine advanced Chinese learners…

  16. WHY DO THE ACUTE BEHAVIORAL EFFECTS OT TOLUENE IN RATS DEPEND ON THE ROUTE OF EXPOSURE?

    EPA Science Inventory

    Despite evidence suggesting that the acute effects of organic solvents are related to their concentration in the brain, we have observed route-dependent differences in the acute behavioral effects of toluene. Whereas inhaled toluene disrupts the performance of rats on a visual si...

  17. 12 CFR 502.15 - How does OTS determine my size component?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... calculate your size component, find the row in Columns A and B that describes your total assets. Reading across in that same row, find your base assessment amount in Column C, your marginal rate in Column D... calculate your size component: If your total assets are: . . . Over—* Column A But not over— Column B Your...

  18. Ursa Major: ot losya do medvedya %t Ursa Major: from elk to bear

    NASA Astrophysics Data System (ADS)

    Lushnikova, A. V.

    In the article material from various cultural and linguistic sources (Indo-European - Slavic, Indo-Iranian; Uralo-Altaic, Tungus, Ancient Egyptian, Babylonian) is used in order to trace up the chronology of the designation of Ursa Majopr, a constellation which has been playing an important role for people different regions since ancient times. It was used for observing of the visible yearly motion of the Sun, for working out seasonal changes; being a circumpolar and non-hiding behind the horizon it has been perceived as a symbol of immortality, its peculiar positional change during a year lay down in plot of the Uralo-Siberian myths about a cosmic hunt for the Elk, myths about deluge. Data from Uralo-Siberian mythology are analyzed. Designations of Ursa Major in the form of a horned hoofed animal such as elk, deer, cow (Uralo-Altaic, Tungus, Slavic, Indo-Iranian languages; Ancient Greece, Crete, Ancient Egypt) and connected with it (or derived from it) denominations and images of "enclosed space" - "vehicle for travelling and carrying goods" (a wagon, a boat) - "instrument for hunting-fishing, a ritual thing" - "household construction" are taken in consideration. The conclusion is made that the transition of the Ursa Major designation from elk to bear could follow the general tendency to shift from so-called matriarchy to patriarchy, to substitute female deities with male ones, which was reflected "in the rise" of the predatory animal cults (not earlier than II mil. B.C.). To prove this, lexical examples of resemblance and coincidences in designation of homed hoofed (elk, deer) and predatory (bear, wolf) animals should be analyzed. Such a goal-directed investigation of the chronology of Ursa Major designations has never been carried out.

  19. Definitize and Prepare Off-The-Shelf (OTS) Electronic Test Equipment (ETE) Specifications

    DTIC Science & Technology

    1978-07-01

    STATED PULSE RAT 5fc60C 04 Oil 9004 10 TO 50MHZ .005 PCT PG6.)B °Z?. 10U 1103 30 2A anooq 0 7421 ooooo 15933 26483 05 J 050...REPETITION »tTE 200H7 TO 20OKH7 .5NSEr TO 100NSEC j TO 100K.HZ 0 TO 2.4MH7 W/100NSEC TO 1SEC 5 T0 3.5MHZ 10 TO...HDL NO fFS’S MCDtL ’ 10 FSC ^I C" ID NC. PAP.SMETEP ACCURACY -PCT- OR AS STATED MTBF SPECIFIF;)/PPi;niCTi=n

  20. OT2_elellouc_2: Pluto's seasonal evolution and surface thermal properties

    NASA Astrophysics Data System (ADS)

    Lellouch, E.

    2011-09-01

    In 2015, Pluto and its system of satellites will be explored by the New Horizons space mission. Pluto is the most prominent representative of large Kuiper-belt objects with volatile ices (N2, CH4, CO) on their surfaces. Due to its elliptic orbit and strong polar inclination, the large seasonal and spatial variability of the insolation is expected to drive global scale transport of the volatile ices, whose thermal balance determines the atmospheric state. Recent observations of Pluto of various kinds have revealed that it is undergoing seasonal evolution, with changes in its atmosphere, surface spectrum, and thermal emission. In particular, Spitzer observations over 2004-2007 indicated a surprising dimming of the dwarf planet at thermal wavelengths, most probably associated with extension of the coldest, N2-ice dominated, regions. We propose to measure the thermal lightcurve of the Pluto/Charon system (i.e. the rotational variation of its thermal emission) with PACS and SPIRE in order to (i) assess the changes in the ice distribution (ii) determine the emissivities (spectral and bolometric) of Pluto's different terrains (iii) determine their thermal inertia on seasonal timescales. These parameters are needed to constrain volatile transport and general circulation models, and to put the upcoming New Horizons measurements in a broader, time-evolving, perspective.

  1. GIOTTO's antenna de-spin mechanism: Ots lubrication and thermal vacuum performance

    NASA Technical Reports Server (NTRS)

    Todd, M. J.; Parker, K.

    1987-01-01

    Except in the near Earth phase of GIOTTO's mission to Comet Halley, the HGA (high gain antenna) on board GIOTTO was the only designed means of up/down communications. The spacecraft spin stabilization required that the HGA be despun at the same rotational rate of nominally 15 rpm in order to keep the HGA pointing accurately to a Earth. A dual servomotor despin mechanism was designed and built by SEP of France for this purpose. The expected thermal environment suggested that dry lubrication was preferable to wet for the ball bearings but there existed no relevant data on the torque noise spectrum of candidate solid lubricants. Therefore ad hoc torque noise tests were run with two solid lubricants: ion plated lead film plus lead bronze cage (retainer) and a PTFE composite cage only. The lead lubrication showed the better spectrum up to the mission lifetime point so it was selected for continued test over some 20 times the Halley mission life, with periodic torque spectrum monitoring. The spectrum remained well within the pointing error budget over the 100 million revolutions covered.

  2. OT2_emurph01_3: The Herschel EDGE-on galaxy Survey (HEDGES)

    NASA Astrophysics Data System (ADS)

    Murphy, E.

    2011-09-01

    We propose deep PACS and SPIRE imaging for all (6) normal, edge-on (i >85 deg) galaxies with d<10Mpc as part of the Herschel EDGEon galaxy Survey (HEDGES). These data will allow us, for the first time, to characterize variations in the far-infrared (FIR) spectral energy distribution (SED) among and within halos for an energetically diverse sample of nearby, edge-on galaxies as a function of height above the disk. The proper sampling of the halo dust SEDs (i.e., 6 bands between 70500um), will allow us to take inventory of the dust content of halos and illuminate the signatures of dust processing imprinted in the dust SED and its variations. These observations will provide a way to address a number of outstanding questions related to the processes governing the interchange of disk/halo material such as: (1) How does halo dust content relate to disk star formation activity? (2) What are the physical characteristics of halo dust (i.e., temperature(s), mass, emissivity, PAH mass fraction, and what does their variation with height from the plane tell us about grain modification by the energetic processes responsible for disk-halo cycling? (3) What can dust and radio continuum halos tell us about transport effects that are important for understanding the FIR-Radio correlation? (4) How does the distribution of halo dust compare to that of other gas tracers, and hence what can we learn about how such dust is associated with various gas phases? The HEDGES sample galaxies have a treasury of ancillary data (e.g., radio, Spitzer, optical, gas), and the addition of these deep Herschel data will make HEDGES the definitive sample to study multi-phase disk/halo feedback processes arising from the accretion, expulsion, and/or cycling of material between disks and halos into the foreseeable future.

  3. Independent evaluation plan for radiac set AN/VDR-1() Operational Test IIA (OT IIA)

    SciTech Connect

    Not Available

    1980-02-01

    The AN/VDR-1() is being developed in response to a DA approved Qualitative Materiel Requirement (QMR) dated 3 March 1971. The radiac system must provide a means of conducting both dismounted and vehicular radiological surveys and for performing radiological monitoring of personnel and equipment. The system will replace both the IM-174/PD and IM-174A/PD radiacmeters and may replace the AN/PDR-27() radiac set. This system is not envisioned for use as an aerial survey meter, since the AN/ADR-6 is currently under development for that specific task. The system will be operated by the individual soldier. A driver should be able to operate it during vehicular radiological surveys. The system will be a TOE issue item to Army units. The equipment will not normally be pooled at higher echelons, except as maintenance floats. The basis of issue will be one system per platoon, company headquarters and subunit requiring a capability to detect low or high level contamination (e.g., medical section). The system will be operated in various climatic and weather conditions. The system will provide the commander with data concerning gamma dose rates in areas contaminated by fallout, neutron-induced gamma activity or radiological agents. This data will assist in the planning of tactical operations and medical monitoring of radiological casualties.

  4. OT1_eegami_4: SPIRE Snapshot Survey of Massive Galaxy Clusters

    NASA Astrophysics Data System (ADS)

    Egami, E.

    2010-07-01

    For deep imaging longward of 100 um, confusion noise sets the fundamental sensitivity limits achievable with Herschel, and these limits cannot be improved by integrating longer. To penetrate through this confusion limit and detect faint high-redshift galaxies, gravitational lensing by massive galaxy clusters offers a very powerful and yet cheap solution. For this reason, we are currently conducting a PACS/SPIRE imaging survey of ~40 massive lensing clusters as one of the Herschel Key Programs, "The Herschel Lensing Survey" (PI: Egami, 292.3 hrs). Although this program is producing many exciting results as reported in our 5 Herschel special-issue papers, one thing is becoming clear: it is extremely difficult to find lensed galaxies that are bright enough (> 200 mJy in SPIRE bands) to perform spectroscopy with PACS/SPIRE. This disappointment, however, was quickly overcome by the serendipitous discovery of an exceptionally bright (~500 mJy@350 um) z=2.3 galaxy lensed by a massive cluster at z=0.325. This discovery suggests that if we survey a large enough cluster sample, we will find similarly bright lensed sources that make all kinds of exciting follow-up observations possible. Here, we propose to conduct such a survey by taking advantage of the Millennium Cluster Sample constructed from the ROSAT All-Sky Survey with many years of extensive follow-ups. More specifically, we will conduct a SPIRE snapshot survey of 279 X-ray-selected clusters. SPIRE's great sensitivity and observing efficiency means that we can complete this program in only 27 hours while achieving a nearly confusion-limited sensitivity of 10 mJy (1 sigma). Such a depth will allow all kinds of secondary science projects as well. Although SPIRE wide-area surveys like H-ATLAS will also discover many bright lensed galaxies, these sources are mostly lensed by galaxies and not clusters, which makes our approach an economic alternative to investigate a different type of lensed systems.

  5. A Guide to Reasonable Accommodation for OT Practitioners with Disabilities: Fieldwork to Employment.

    ERIC Educational Resources Information Center

    Wells, Shirley A., Comp.; Hanebrink, Sandy, Comp.

    This handbook provides information to occupational therapy clinicians and students with disabilities, fieldwork educators, and employers on issues of accommodation, disclosure, rights, responsibilities, and the Americans with Disabilities Act (ADA). It begins with a discussion of the disability rights movement, and employment and people with…

  6. OT1_cjoblin_1: Physics of gas evaporation at PDR edges

    NASA Astrophysics Data System (ADS)

    Joblin, C.

    2010-07-01

    Far-ultraviolet (FUV) photons in massive OB star-forming regions have a major impact on the structure, dynamics, chemistry and thermal balance of their associated molecular cloud. We propose to study the photoevaporation under FUV irradiation of dense filaments in prototype photodissociation regions (PDR) by mapping with the HIFI spectrometer the [CII] 158 micron line associated with the evaporating gas and high-J CO lines tracing the warm dense structures. The combination of the spectral range covered by Herschel and the very high spectral resolution of HIFI is unique to get insight into the process of mixing of cold molecular gas into warm atomic gas. This process governs the evolution of dense gas submitted to FUV photons in a wide variety of astronomical objects including protostellar and protoplanetary disks but is best studied in PDRs. We ask for 9.8 hours of observations in two PDRs, NGC7023 and the Horsehead nebula. NGC7023 is illuminated by a B2Ve star and hosts very diluted atomic gas and dense filaments. The Horsehead nebula is a PDR viewed nearly edge-on with a high gas density gradient at the edge that is illuminated by a O9.5V star and is immersed in an HII region. In these objects, there is evidence for dynamical processes that create a mixing layer between molecular and atomic gas, both from gas kinematics (first results with HIFI on the [CII] line) and chemistry. The first HIFI [CII] results clearly call for a larger spatial coverage of the region using OTF mapping mode with HIFI to obtain a more complete picture of the PDR morphology and dynamics. The 12^CO(8-7) and 13^CO(8-7) lines will be also targeted to trace the warm interfaces of the dense filaments/edges. The team gathers together specialists of the studied regions and of the Herschel instruments: HIFI (this proposal), SPIRE and PACS (complementary data). The team has strong expertise in the study of the physics and chemistry of PDRs, both in terms of data analysis and modelling using and developing the Meudon PDR code.

  7. OT2_dteyssie_2: Unveiling the water puzzle in cold PDRs: The Horsehead case

    NASA Astrophysics Data System (ADS)

    Teyssier, D.

    2011-09-01

    While Herschel observations of water vapour in warm regions (T_gas >> 100 K) driven by energetic processes (outfows, shocks, hot cores, etc.) have confirmed large abundances of water vapour (~10^-5), the inferred gas phase H2O abundance in dark clouds is very low, ~10^-10. A detailed balance between freeze-out, ice-mantle desorption and gas-phase chemistry is required to explain this orders-of-magnitude abundance difference. The Horsehead nebula is particularly well-suited to investigate grain surface chemistry in a UV irradiated environment. Its relatively low UV illumination (~60 in Draine units) implies low dust grain temperatures, from T_dust=30K in the PDR to T_dust=20K deeper inside the cloud. Therefore, the release of the grain mantle products into the gas phase, water vapour in particular, is dominated by UV-induced photo-desorption and not by thermal evaporation (as in other warm PDRs such as the Orion Bar). Besides, owing to its simple edge-on geometry, the Horsehead is very close to the prototypical kind of source needed to serve as model benchmark. A relatively low water vapour beam-averaged abundances (~5x10^-9) was derived from a single position of the o-H2O ground-state line towards the so-called "IR peak" of the Horsehead PDR. However a detailed comparison with sophisticated PDR models including gas and grain chemistry is not possible due to our complete ignorance about the true H2O spatial distribution as one moves from the UV-illuminated cloud surface to the inner shielded cloud. We propose here to map with HIFI the o-H2O 557 GHz line on a cut across the PDR front, and extract the spatial information required to constrain the role of water freeze-out and water ice photodesorption as a function of cloud depth.

  8. Applying graphics user interface ot group technology classification and coding at the Boeing aerospace company

    NASA Astrophysics Data System (ADS)

    Ness, P. H.; Jacobson, H.

    1984-10-01

    The thrust of 'group technology' is toward the exploitation of similarities in component design and manufacturing process plans to achieve assembly line flow cost efficiencies for small batch production. The systematic method devised for the identification of similarities in component geometry and processing steps is a coding and classification scheme implemented by interactive CAD/CAM systems. This coding and classification scheme has led to significant increases in computer processing power, allowing rapid searches and retrievals on the basis of a 30-digit code together with user-friendly computer graphics.

  9. Synthesis of ZnO nanoparticles for varistor applications using Zn-substituted aerosol OT microemulsion

    SciTech Connect

    Singhal, M.; Chhabra, V.; Kang, P.; Shah, D.O.

    1997-02-01

    This paper describes a new method for the synthesis of zinc oxide nanoparticles using ethanol-in-oil microemulsions with Zn-DEHSS (diethylhexyl sulfosuccinate) as surfactant. The zinc oxide nanoparticles find application in varistors and other functional devices. These particles have been characterized by X-ray diffraction, TEM, and BET surface area. Microemulsion droplets were characterized by quasi elastic light scattering (QELS). Varistors formed from doped zinc oxide nanoparticles finds application as low voltage surge devices with low leakage current and high coefficient of nonlinearity ({alpha}). In this paper, the authors have shown that the critical voltage of the varistor is related to the grain size which is related to size of ZnO particles. The smaller ZnO particles lead to larger grain size, thereby lowering the critical voltage.

  10. OT2_amoor_4: A census of debris disks in nearby young moving groups with Herschel.

    NASA Astrophysics Data System (ADS)

    Moór, A.

    2011-09-01

    Nearly all young stars harbour circumstellar disks, that serve as the reservoir for mass accretion onto the star, and later become the birthplace of planetary systems. After the disappearance of the gas component from the disk a dusty debris disk is formed that is believed to mark the location of the planetesimal belt as well. For outlining the evolution of such debris disks traditionally open clusters and field stars were studied, however we argue that the recently discovered young moving groups are more suitable objects for such analyses, due to their proximity and good coverage of the first 50 Myr period of the planetary system evolution. In this proposal we request 70/160 um Herschel/PACS photometric observations for so-far unobserved moving group members. These observations will provide a complete coverage of all known members within 80 pc of five nearby young moving groups (beta Pic Moving Group, Tucana-Horologium, Carina, Columba, and Argus), in the A to K spectral range. Based on the new observations we will identify new debris disks, characterize the disk population within individual moving groups, and study disk evolution by comparing the groups of different ages. The results will be used to verify predictions of the self-stirring model of the evolution of planetesimal disks. We will also compare the properties of debris disks in groups of the same age, looking for additional 'environmental' parameters that affect disk structure over a whole moving group. Our study will be a significant contribution to the census of debris disks in young moving groups, increasing the number of observed sources by a factor of 1.5. Since Spitzer could perform only a limited census and the so-far approved Herschel programs added very few additional moving group obervations, our programme is expected to have a high legacy value.

  11. OT2_ctibbs_1: Exploring the role of CII in current Spinning Dust Models

    NASA Astrophysics Data System (ADS)

    Tibbs, C.

    2011-09-01

    We propose HIFI observations of the CII fine structure line at 158 micron (1.9THz) in 22 pointings distributed across four Galactic anomalous emission regions (the Perseus cloud, LDN 1780, LDN 675 and LDN 1111). The currently favoured explanation for the observed anomalous microwave emission is that of electric dipole radiation from rapidly rotating small dust grains (PAHs and/or VSGs), commonly referred to as spinning dust. Although this hypothesis predicts that the source of the excess emission is due to dust, the small dust grains are sensitive to the ionisation state of the gas, and hence the spinning dust models have a dependancy on the abundance of the major gas ions. CII observations will enable us to investigate this dependancy, and combining these observations with the available mid- to far-IR observations will permit a complete analysis of the role of both the dust and gas in regions of anomalous emission. We request a total of 14.9 hrs of HIFI observing time.

  12. OT1_rpaladin_1: PACS and SPIRE observations of Galactic anomalous emission sources.

    NASA Astrophysics Data System (ADS)

    Paladini, R.

    2010-07-01

    Despite the increasing evidence that the anomalous emission is a new physical mechanism acting in the diffuse interstellar medium, the nature and distribution of this component remains elusive. The currently most favored models attribute the observed microwave excess to rotating very small dust grains (PAHs and VSGs). Nonetheless, the infrared properties of the sources which, to date, are known to exhibit this type of emission are very poorly known mostly due to the limited angular resolution and frequency coverage of DIRBE and IRAS data. We propose HERSCHEL PACS and SPIRE mapping of three Galactic anomalous emission sources (LDN 1780, LDN 675 and LDN 1111). This data, when combined with ancillary NIR and mid-IR data of comparable angular resolution (mainly from Spitzer), and coupled with available dust models, will allow to set tight constraints on the radiation field in the emitting sources as well as in their immediate surroundings. Such constraints, in turn, will allow to estimate the abundances of PAHs, VSGs and BGs, hence to shed light on the potential link between these dust populations and the observed microwave excess.

  13. OT2_cmccoey_3: Evolution of water emission in intermediate mass YSOs

    NASA Astrophysics Data System (ADS)

    McCoey, C.

    2011-09-01

    Intermediate mass YSOs are studied as part of the WISH KP. We find our source sample is too limited to identify properties associated with stellar evolution. With this proposal we ask for time to observe two more intermediate mass YSOs with HIFI and PACS. When looking at line profiles among or source set a confused picture appears. NGC 7129 FIRS 2 and LDN 1641 are both Class 0 YSOs but have very different line profiles. Similarly, the Vela sources are both Class I sources and even have almost the same bolometric luminosity but display very different spectra. It is noteworthy that line profiles of the Class 0 NGC 7129 FIRS 2 are very similar to the line profiles of the Class I Vela IRS 17. Furthermore, the most evolved source, AFGL 490, is most similar, albeit brighter, to one of the least evolved sources, LDN 1641. We require more observations in order to assess if there is any relation in line profile with evolutionary state. We ask for time to observe the Class 0 intermediate YSO, Cep E-mm, and the Class I/II sources, LkHa 224.

  14. OT1_amoromar_1: Herschel observations of solar-type stars with planets, planetesimals and dust

    NASA Astrophysics Data System (ADS)

    Moro-Martín, A.

    2010-07-01

    Similar to the Solar system, there are only 18 planetary systems known to harbor planets and planetesimals. This small sample is of unique value to our understanding of the diversity, dynamical history, and formation mechanisms of extra-solar planetary systems. Here we propose to observe seven of these systems, with spectral types F7-K2 and ages from 0.5-6.4 Gyr. They all show excess emission at 70 um but not at 24 um, implying the presence of an inner region depleted of warm dust, resembling the Solar System in its Jovian planets + Kuiper belt configuration. It is possible to characterize their planetesimal belts from the study of their dust disks. However, the disks SEDs are not known beyond 70 um. Long wavelength observations are of fundamental importance to determine the presence of cold grains, the only tracer of the outer edge of the dust-producing planetesimal belts. Because the latter is a critical parameter to understand the dynamical history and formation of these systems, we propose to carry out PACS 70/160 and SPIRE observations with the main goal of constraining the SEDs at long wavelengths. We have selected PACS 70 to take full advantage of the Herschels improved spatial resolution at 70 um compared to Spitzer, opening the opportunity to resolve the cold dust component that traces the planetesimal belt (which extent could be related to the dynamical history of the planetary system), and to detect extended halos (thought to arise from small dust grains on highly eccentric or hyperbolic orbits, that likely relate to the level of dynamical activity in the planetesimal belt). This proposal requires a total of 11.6 hours. The results will increase our understanding of the diversity of planetary systems, helping us place our Solar system into context. Herschel is the only observatory that can carry out the observation required for this study because of its high sensitivity in the wavelength range where the peak of the dust emission may be located.

  15. OT1_dneufeld_2: The puzzle of water vapour in carbon-rich stars

    NASA Astrophysics Data System (ADS)

    Neufeld, D.

    2010-07-01

    Using the HIFI instrument, we will address the puzzling - but widespread - appearance of water vapour in carbon-rich stars. Following up on detections of water in ALL SIX carbon-rich AGB stars observed to date in a pilot study performed in the HIFISTARS Key Program, we will target additional water transitions in four stars already observed or expected to show the most luminous water emissions. The target stars are CIT6, IRAC 15194-5155, V Cygni, and S Cep, and the additional transitions are the 4(22)-3(31) and 3(12) - 2(21) transitions at 916 GHz and 1153 GHz. Combined with spectra already obtained for the low-lying water transitions, and interpreted in the context of water excitation models, the proposed observations will place strong constraints upon the location of the emitting water. We will therefore be able to distinguish between various hypotheses that have been proposed for the origin of the observed water: the vaporization of orbiting comets or dwarf planets; catalytic formation on dust grains; or chemical processes initiated by the photodissociation of CO. In addition, we will carry out deep integrations to observe the lowest 1(11) - 0(00) transition of para-water at 1113 GHz in two carbon-rich AGB stars: IRAS+40540 and V Hya; here, ortho-water has been securely detected but existing observations of the 1113 GHz para-water line yield weak detections that lack the signal-to-noise ratio needed to constrain the ortho-to-para ratio.

  16. OT2_fwyrowsk_3: A Water survey of massive star forming clumps in the inner Galaxy

    NASA Astrophysics Data System (ADS)

    Wyrowski, F.

    2011-09-01

    Water, as a dominant form of oxygen, the most abundant element in the universe after H and He, controls the chemistry of many other species. It is a unique diagnostic of warm gas and energetic processes taking place during star formation. We therefore propose to exploit the unique opportunity of Herschel to study water in large, statistically significant, flux limited samples of massive star forming regions detected in the recently completed ATLASGAL submm dust continuum survey of the inner Galactic plane. In the last years, our view of massive star forming regions has dramatically changed by Galactic plane surveys covering cm to IR wavelengths. These surveys enable us for the first time to study ALL evolutionary stages of massive star formation (MSF) in an unbiased way. Water, acting as a natural filter for warm, dense gas, allows to probe the chemical and physical conditions in all of these stages close to where the massive stars are forming or just have been formed. ATLASGAL observed submm dust continuum emission as best tracer of the earliest phases of MSF since it is directly probing the material from which the stars form. As a large unbiased survey it provide the statistical base to study the scarce and short-living protoclusters as the origin of the massive stars and the richest clusters in the Galaxy and supplies us with a legacy value sample of MSF regions for the water follow ups. Water is typically seen with strongly increased abundances in broad line wings, providing a new, sensitive probe of shocked outflowing gas. In addition, the envelope is probed in a combination of absorption and emission with a clear jump in abundance in the warm inner regions close to the forming massive stars. Only Herschel can provide a water survey of a large sample of ATLASGAL selected sources to study water through the evolution of massive star forming regions with a statistically significant sample size.

  17. WHY DO THE ACUTE BEHAVIORAL EFFECTS OT TOLUENE IN RATS DEPEND ON THE ROUTE OF EXPOSURE?

    EPA Science Inventory

    Despite evidence suggesting that the acute effects of organic solvents are related to their concentration in the brain, we have observed route-dependent differences in the acute behavioral effects of toluene. Whereas inhaled toluene disrupts the performance of rats on a visual si...

  18. Swift UVOT observations of the SMC nova MASTER OT J010603.18-744715.8

    NASA Astrophysics Data System (ADS)

    Kuin, N. P. M.; Page, K. L.; Williams, S. C.; Darnley, M. J.; Shore, S. N.; Walter, F. M.

    2016-10-01

    Since its discovery at magnitude 10.9 on 2016-10-14.19341 UT (Shumkov et al, ATEL #9621) and spectroscopic confirmation (Williams and Darnley, ATEL #9628) pre-discovery data from the OGLE team (Mroz and Udalski, ATEL #9622, and MASTER (Lipunov et al., ATEL #9631) revealed the progenitor magnitude and pushed back the appearance of the nova to magnitude 8.5 on 2016, Oct 9.808.

  19. 12 CFR 563b.240 - What must I submit to OTS after the members' meeting?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... TREASURY CONVERSIONS FROM MUTUAL TO STOCK FORM Standard Conversions Vote by Members § 563b.240 What must I...) The total votes cast in favor of and against each matter. (5) The percentage of votes necessary to approve each matter. (6) An opinion of counsel that you conducted the members' meeting in compliance...

  20. 12 CFR 563b.240 - What must I submit to OTS after the members' meeting?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... TREASURY CONVERSIONS FROM MUTUAL TO STOCK FORM Standard Conversions Vote by Members § 563b.240 What must I...) The total votes cast in favor of and against each matter. (5) The percentage of votes necessary to approve each matter. (6) An opinion of counsel that you conducted the members' meeting in compliance...

  1. OTS: a program for converting Noldus Observer data files to SDIS files.

    PubMed

    Bakeman, R; Quera, V

    2000-02-01

    A program for converting Noldus Observer data files (ODF) to sequential data interchange standard (SDIS) files is described. Observer users who convert their data files can then take advantage of various flexible and powerful data modification and computational procedures available in the Generalized Sequential Querier, a program that assumes SDIS-formatted files.

  2. Management of Operational Test and Evaluation (OT&E) in Strategic Air Command.

    DTIC Science & Technology

    1985-04-01

    TLE o r n,,r I"r .i -d ’S, C .- Chaptef- CIne pr- set.c rt t - r; er. t ;.. , r - he r - ear ch tudi. In Ch.a p ter. T , . det .- i i d a- s t, -i- h...we haue are only as good as the process we use t o *~.-luate them. Z.3 i I BIBLIO GRAPHY A. REFERENCES CITE’E .. Articles and Periodicals t. "T !<ng

  3. The Temperature Dependence of Ice Viscosity (Vyazkost Lda v Zavisimosti ot Temperatury),

    DTIC Science & Technology

    The role and significance of crystalline structure in the study of the plastic properties of ice has been demonstrated. An anomalous change in the...rate of plastic deformation of specimens of sufficiently regular crystalline structure occurs when they are subjected to sharp change in temperature

  4. OT1_hmaness_1: Planets, Debris Disks, and the Lambda Bootis Stars

    NASA Astrophysics Data System (ADS)

    Maness, H.

    2010-07-01

    We propose to explore the link between lambda Bootis stars, debris disks, and planetesimal formation and evolution. The lambda Boo stars are a rare type of peculiar A star (2%), which are Population 1 and metal poor. Planet bearing systems and debris disk stars appear unusually well represented in the lambda Boo class: for example, beta Pic, Vega, and HR 8799 are all lambda Boo candidates. A small sample of 14 lambda Boo stars observed by Spitzer suggests an occurrence of infrared excess approaching 100%. Only two lambda Boo stars are included in the DEBRIS/DUNES Herschel key program debris disk surveys. We will use PACS/Herschel to make sensitive, high-resolution maps of 27 new lambda Boo stars. Like DEBRIS/DUNES, we will reach the stellar photosphere for all targets, enabling a measurement of the true rate of excess infrared emission among lambda Boo stars compared to normal A stars. The depletion pattern of heavy elements in the atmospheres of lambda Boo stars suggests they may have accreted gas from which dust grains have condensed and been removed: this gas may be circumstellar gas that has formed planetesimals or dusty interstellar gas. While the circumstellar disk scenario predicts sizes of a few hundred AU, the cloud accretion scenario predicts 1000-2000 AU bow structures oriented in the direction of the relative motion of the cloud and star. With target distances of < 140 pc, these bow structures are expected to be resolved for all targets. These will be the first mid-infrared observations of lambda Boo stars outside of the low density Local Bubble: if interstellar medium interactions dominate the lambda Boo phenomenon then systematic variations in excess strength and morphology may occur with distance.

  5. OT1_jgreen02_2: FOOSH: FU Orionis Objects Surveyed with Herschel

    NASA Astrophysics Data System (ADS)

    Green, J.

    2010-07-01

    We propose to utilize the unprecedented spatial resolution and sensitivity of Herschel at far-infrared and submm wavelengths to observe nearly all known FU Orionis objects, the dramatic result of burst accretion events in protostellar disks. The known FUors represent a vital window into a key process of star formation rather than a rare and peculiar event in the lives of a few stars. In addition, FUors provide a natural laboratory that probes the effect on enhanced heating on disk composition and structure. Our objectives are to (1) Study the structure of known envelopes and constrain the amount of remnant envelope material around the remainder; (2) characterize the physical and chemical properties of the disks and envelope, the parameters that set the initial conditions for planet formation in T Tauri disks; (3) observe solid-state, atomic, and molecular spectral features toward FUors in order to determine the effects of increased luminosity on mineralogy, disk chemistry, and envelope material. In order to do this we will use all three instruments onboard Herschel, providing a comprehensive survey of FUors.

  6. Local and Global Magnetic Fields of Late-Type Dwarfs OT Ser and YZ CMi

    NASA Astrophysics Data System (ADS)

    Bychkov, V. D.; Bychkova, L. V.; Madej, J.; Panferov, A. A.

    2015-04-01

    Differential rotation is the primary energy source for generation of local magnetic fields in the atmospheres of late-type stars (Moss et al. 1995). Moreover, the colder a star, the greater the effect, which was confirmed by observations. For instance, Saar (1988) measured the surface magnetic fields of late-type stars using the integral method Robinson (1980) and drew attention to the fact that the average magnetic field in the spots reaches the values of 1500 G for the G-type dwarfs, 2500 G for the K dwarfs, and 3500 G for the M-dwarf stars. The fraction of the surface of a star covered by spots also increases towards the latest spectral types. These well-known observational facts were explained by theoretical models, such as the α2 mechanism, for instance (Moss et al. 1995). Late-type dwarfs exhibit periodic eruptions resulting from the field line reconnection of newly generated local magnetic fields. This feature is observed in G, K, and M dwarfs, constituting 95%of all the stars in our Galaxy. The most prominent are the field reconnections in the so-called flare stars, which are the M dwarfs. This is understandable, since the peak flux of M dwarfs is placed in the red and infrared regions of the spectrum, whereas a flash has the maximum emission in the violet spectral region. Analysis of long-term photometric observations revealed that, on the average, energy of flares was found constant over a long time period for each flare star. That is to say, this conclusion implies that the power of the local magnetic field generator remains constant at this stage of evolution of stars.

  7. Visible-light driven water splitting over BiFeO₃ photoanodes grown via the LPCVD reaction of [Bi(OtBu)₃] and [Fe(OtBu)₃]₂ and enhanced with a surface nickel oxygen evolution catalyst.

    PubMed

    Moniz, Savio J A; Blackman, Christopher S; Southern, Paul; Weaver, Paul M; Tang, Junwang; Carmalt, Claire J

    2015-10-21

    Phase-pure BiFeO3 films were grown directly via dual-source low-pressure CVD (LPCVD) from the ligand-matched precursors [Bi(O(t)Bu)3] and [Fe(O(t)Bu)3]2, without the requirement for oxidising gas or post deposition annealing. Photocatalytic testing for water oxidation revealed extremely high activity for PEC water splitting and photocatalytic water oxidation under visible light irradiation (λ > 420 nm) with a benchmark IPCE for BiFeO3 of 23% at 400 nm. The high activity is ascribed to the ultrafine morphology achieved via the LPCVD process. The performance was enhanced by over four times when the BiFeO3 photoanode is coupled to a Ni-B surface OEC.

  8. Multilocus phylogenetic analysis of true morels (Morchella) reveals high levels of endemics in Turkey relative ot other regions of Europe

    USDA-ARS?s Scientific Manuscript database

    The present study was conducted to better understand how the phylogenetic diversity of true morels (Morchella) in Turkey compares with species found in other regions of the world. The current research builds on our recently published survey of 10 Turkish provinces and another of the world in which D...

  9. Software Supportability Risk Assessment in OT&E (Operational Test and Evaluation): Historical Baselines for Risk Profiles. Volume 1.

    DTIC Science & Technology

    1985-10-07

    ORS OC-ALC 8-52 BNST OC-ALC B-52 FTSS OC-ALC 8-52 MC-1 EXEC 00-ALC B-52 MC-2 EXEC OC-ALC E- 3 INS OC-ALC E-3A OMEGA OC-ALC E-3A SMCP OC-ALC E-3A SRCP OC...293 SOFTIAR SWORTRILITY RISK ASSESSMENT IN OTAin 3 (OPERRTIONAL TEST RIM EVA.. (U) ION CORP RLIIUIERWE ENY TI.f CT9 W-5050T-O- WCMLSSIFIED F2901-U...lb. 1*ESTfl.CTIVI; MA04KING.- N/A None .SECURITY~ CLASSIFICATION AbUTNOAITY 3 . OISRIUUTION/AVAILAUILITY UPF MIORT N/A Unlimited -- O CLASSI P SCAT

  10. Crystal structure of product-bound complex of UDP-N-acetyl-D-mannosamine dehydrogenase from Pyrococcus horikoshii OT3

    SciTech Connect

    Pampa, K.J.; Lokanath, N.K.; Girish, T.U.; Kunishima, N.; Rai, V.R.

    2014-10-24

    Highlights: • Determined the structure of UDP-D-ManNAcADH to a resolution of 1.55 Å. • First complex structure of PhUDP-D-ManNAcADH with UDP-D-ManMAcA. • The monomeric structure consists of three distinct domains. • Cys258 acting as catalytic nucleophilic and Lys204 acts as acid/base catalyst. • Oligomeric state plays an important role for the catalytic function. - Abstract: UDP-N-acetyl-D-mannosamine dehydrogenase (UDP-D-ManNAcDH) belongs to UDP-glucose/GDP-mannose dehydrogenase family and catalyzes Uridine-diphospho-N-acetyl-D-mannosamine (UDP-D-ManNAc) to Uridine-diphospho-N-acetyl-D-mannosaminuronic acid (UDP-D-ManNAcA) through twofold oxidation of NAD{sup +}. In order to reveal the structural features of the Pyrococcus horikoshii UDP-D-ManNAcADH, we have determined the crystal structure of the product-bound enzyme by X-ray diffraction to resolution of 1.55 Å. The protomer folds into three distinct domains; nucleotide binding domain (NBD), substrate binding domain (SBD) and oligomerization domain (OD, involved in the dimerization). The clear electron density of the UDP-D-ManNAcA is observed and the residues binding are identified for the first time. Crystal structures reveal a tight dimeric polymer chains with product-bound in all the structures. The catalytic residues Cys258 and Lys204 are conserved. The Cys258 acts as catalytic nucleophile and Lys204 as acid/base catalyst. The product is directly interacts with residues Arg211, Thr249, Arg244, Gly255, Arg289, Lys319 and Arg398. In addition, the structural parameters responsible for thermostability and oligomerization of the three dimensional structure are analyzed.

  11. Topographic form of the Coast Ranges of the Cascadia Margin in relation ot coastal uplift rates and plate subduction

    NASA Technical Reports Server (NTRS)

    Kelsey, Harvey M.; Engebretson, David C.; Mitchell, Clifton E.; Ticknor, Robert L.

    1994-01-01

    The Coast Ranges of the Cascadia margin are overriding the subducted Juan de Fuca/Gorda plate. We investigate the extent to which the latitudinal change in attributes related to the subduction process. These attributes include the varibale age of the subducted slab that underlies the Coast Ranges and average vertical crustal velocities of the western margin of the Coast Rnages for two markedly different time periods, the last 45 years and the last 100 kyr. These vertical crustal velocities are computed from the resurveying of highway bech marks and from the present elevation of shore platforms that have been uplifted in the late Quaternary, respectively. Topogarphy of the Coast Ranges is in part a function of the age and bouyancy of the underlying subducted plate. This is evident in the fact that the two highest topographic elements of the Coast Rnages, the Klamath Mountains and the Olympic Mountains, are underlain by youngest subducted oceanic crust. The subducted Blanco Fracture Zone in southernmost Oregon is responsible for an age discontinuity of subducted crust under the Klamath Mountains. The norhtern terminus of hte topographically higher Klamaths is offset to the north relative to the position of the underlying Blanco Fracture Zone, teh offset being in the direction of migration of the farcture zone, as dictated by relative plate motions. Vertical crustal velocities at the coast, derived from becnh mark surveys, are as much as an order of magnitude greater than vertical crustal velocities derived from uplifted shore platforms. This uplift rate discrepancy indicates that strain is accumulating on the plate margin, to be released during the next interplate earthquake. In a latitudinal sense, average Coast Rnage topography is relatively high where bench mark-derived, short-term vertical crustal velocities are highest. Becuase the shore platform vertical crustal velocities reflect longer-term, premanent uplift, we infer that a small percentage of the interseismic strain that accumulates as rapid short-term uplift is not recovered by subduction earthquakes but rather contributes to rock uplift of the Coast Ranges. The conjecture that permanent rock uplift is related to interseismic uplift is consistent with the observation that those segments of the subduction zone subject to greater interseismic uplift rates are at approximately the same latitudes as those segments of the Coast Ranges that have higher magnitudes of rock uplift over the long term.

  12. Topographic form of the Coast Ranges of the Cascadia Margin in relation ot coastal uplift rates and plate subduction

    NASA Astrophysics Data System (ADS)

    Kelsey, Harvey M.; Engebretson, David C.; Mitchell, Clifton E.; Ticknor, Robert L.

    1994-06-01

    The Coast Ranges of the Cascadia margin are overriding the subducted Juan de Fuca/Gorda plate. We investigate the extent to which the latitudinal change in attributes related to the subduction process. These attributes include the varibale age of the subducted slab that underlies the Coast Ranges and average vertical crustal velocities of the western margin of the Coast Rnages for two markedly different time periods, the last 45 years and the last 100 kyr. These vertical crustal velocities are computed from the resurveying of highway bech marks and from the present elevation of shore platforms that have been uplifted in the late Quaternary, respectively. Topogarphy of the Coast Ranges is in part a function of the age and bouyancy of the underlying subducted plate. This is evident in the fact that the two highest topographic elements of the Coast Rnages, the Klamath Mountains and the Olympic Mountains, are underlain by youngest subducted oceanic crust. The subducted Blanco Fracture Zone in southernmost Oregon is responsible for an age discontinuity of subducted crust under the Klamath Mountains. The norhtern terminus of hte topographically higher Klamaths is offset to the north relative to the position of the underlying Blanco Fracture Zone, teh offset being in the direction of migration of the farcture zone, as dictated by relative plate motions. Vertical crustal velocities at the coast, derived from becnh mark surveys, are as much as an order of magnitude greater than vertical crustal velocities derived from uplifted shore platforms. This uplift rate discrepancy indicates that strain is accumulating on the plate margin, to be released during the next interplate earthquake. In a latitudinal sense, average Coast Rnage topography is relatively high where bench mark-derived, short-term vertical crustal velocities are highest. Becuase the shore platform vertical crustal velocities reflect longer-term, premanent uplift, we infer that a small percentage of the interseismic strain that accumulates as rapid short-term uplift is not recovered by subduction earthquakes but rather contributes to rock uplift of the Coast Ranges. The conjecture that permanent rock uplift is related to interseismic uplift is consistent with the observation that those segments of the subduction zone subject to greater interseismic uplift rates are at approximately the same latitudes as those segments of the Coast Ranges that have higher magnitudes of rock uplift over the long term.

  13. OT1_sbontemp_1: Water emission from outflows and hot cores in the Cygnus X proto-stars

    NASA Astrophysics Data System (ADS)

    Bontemps, S.

    2010-07-01

    The impressive first results from the WISH GT key program by van Dishoeck et al. indicate that water emission is bright towards the embedded proto-stars of all masses. These emissions are tracing outflows and warm inner regions of the collapsing envelopes (radiatively heated hot cores) which are unique probes of the cooling of these regions and of the kinematics of the dense warm gas. But WISH is limited by the reduced number of targets, and by the unavoidable biases introduced by the stringent selection of sources. The intermediate to high mass range is critical to challenge protostellar evolution models, and we argue that water emission from a complete sample of proto-stars in this mass range will be an important piece of knowledge for outflows to trace indirectly accretion and for hot cores to follow their time of appearance. Only Cygnus X is nearby and rich enough to provide a large sample of such proto-stars. We propose here to dramatically change the level of significance of WISH results by observing as many as 92 proto-stars covering the (final stellar) mass range of 3 to 20 Msun in the single complex of Cygnus X.

  14. OT1_dweedman_1: Comparing [CII] 158 micron Luminosities to Spectral Properties of Luminous Starburst Galaxies and AGN

    NASA Astrophysics Data System (ADS)

    Weedman, D.

    2010-07-01

    Herschel PACS spectroscopy of the [CII] emission line at 158 microns is proposed for a carefully selected sample of 123 sources that already have complete low and high resolution mid-infrared spectra between 5 microns and 35 microns from the Spitzer Infrared Spectrograph, and which also have spectral energy distributions (SEDs) from IRAS and Akari photometry. [CII] 158 um is the strongest far-infrared emission line and therefore crucial to compare with other features in luminous, dusty galaxies. Sources have 0.004 < z < 0.34 and 43.0 < log L(IR) < 46.8 (erg per sec) and cover the full range of starburst galaxy and AGN classifications. Obtaining these [CII] line fluxes with PACS will allow: 1. determining how precisely [CII] luminosity measures star formation rate by comparing to PAH features and emission lines that arise in starburst galaxies; 2. determining how [CII] luminosity and equivalent width changes with starburst/AGN fraction, by comparing with strength and equivalent width of PAH and [NeII] emission arising from starbursts, and with strength of high ionization lines [NeV] and [OIV] and silicate absorption or emission arising from AGN; 3. determining how [CII] luminosity and equivalent width changes with dust temperature and bolometric luminosity, as derived from spectral energy distributions, and whether this depends on the starburst/AGN fraction. These determinations will allow interpretation of high redshift sources for which the only available diagnostics are the luminosity and equivalent width of the [CII] line and the far-infrared rest-frame SED. The total observing program requires 20.2 hours of Herschel observing time.

  15. Learning in a Simulation-OT in Heart Surgery and the Challenges of the Scientification of Work

    ERIC Educational Resources Information Center

    Langemeyer, Ines

    2014-01-01

    Enhancing competency and collaboration has become a salient topic of the professional debate on medical safety issues. The advantages of simulation-based training scenarios for team communication, routines and critical work procedures especially in operation theatres have been vigorously discussed. However, the literature on simulation-based…

  16. Free Energy of the Three-Dimensional Spin-12 Quantum Heisenberg Model to O[T6

    NASA Astrophysics Data System (ADS)

    Chang, Chih-chun

    2001-11-01

    By applying the Friedberg-Lee-Ren's theorem (Ann. Phys. (N.Y.) 228, 52 (1993)) to the spin-12 three-dimensional isotropic quantum Heisenberg system, we obtain the low-temperature expansion of the free energy through a field theoretical calculation done in the equivalent lattice boson system. We reproduced Dyson's result and also extended it from T5 to T6. Nevertheless, because of the peculiar property of the spin operator being neither bosonic nor fermionic, the extension is not easy to obtain by other method.

  17. ICT & OTs: a model of information and communications technology acceptance and utilisation by occupational therapists (part 2).

    PubMed

    Schaper, Louise; Pervan, Graham

    2007-01-01

    The research reported in this paper describes the development, empirical validation and analysis of a model of technology acceptance by Australian occupational therapists. The study described involved the collection of quantitative data through a national survey. The theoretical significance of this work is that it uses a thoroughly constructed research model, with one of the largest sample sizes ever tested (n=1605), to extend technology acceptance research into the health sector. Results provide strong support for the model. This work reveals the complexity of the constructs and relationships that influence technology acceptance and highlights the need to include sociotechnical and system issues in studies of technology acceptance in healthcare to improve information system implementation success in this arena. The results of this study have practical and theoretical implications for health informaticians and researchers in the field of health informatics and information systems, tertiary educators, Commonwealth and State Governments and the allied health professions.

  18. OT1_rrubin_1: Herschel's Opportunity to Solve the Nebular Abundance Problem While Creating a Legacy Planetary Nebulae Dataset

    NASA Astrophysics Data System (ADS)

    Rubin, R.

    2010-07-01

    Abundance surveys of a large sample of Galactic planetary nebulae (PNe) have led to the discovery of a group of super-metal-rich nebulae whose spectra show prominent optical recombination lines (ORLs) from C, N, O, and Ne ions. The heavy element abundances derived from ORLs for several PNe are a factor >10 higher than those derived from the traditional method based on collisionally excited lines (CELs). This ratio is called the abundance discrepancy factor (adf). A promising proposition to explain the nebular abundance problem posits that these nebulae contain (at least) two distinct regions - one of "normal" electron temperature, Te (~10000 K) and chemical composition (~solar) and another of very low Te (< 1000) that is H-deficient, thus having high metal abundances relative to H. The latter component emits strong heavy element ORLs and IR fine-structure (FS) CELs but essentially no optical/UV CELs. Efforts to directly detect these inclusions in PNe have been unsuccessful to date. However, there is mounting circumstantial evidence for their existence, such as presented in our recent paper that modeled the high-adf PN NGC 6153 using a 3-D photoionization code. The models that included the low Te, H-deficient knots fit most observations far better than did those models without the clumps. With the launch of Herschel, there is finally the capability to perform a test we've been dreaming of. Measurements have shown that the adf varies with position in a PN and is highest close to the central star. The very low Te inclusions must be cooled via FS IR lines. We propose to use Herschel to map the FS IR lines in 5 bright PNe on the largest adf list, to find if these lines peak where the adf peaks. These spectra will also provide a feast for our other team expertise/interests: a legacy dataset of molecular lines to explore PDRs, how the central star interacts with the AGB ejecta and shapes the PN, how the shocks are produced, what comprises the chemistry of the molecular ejecta, and how do PNe evolve.

  19. "[N]ot subject to our sense” : Margaret Cavendish's fusion of Renaissance science, magic and fairy lore.

    PubMed

    Walters, Lisa

    2010-01-01

    This article explores Margaret Cavendish's depictions of alchemy, witchcraft and fairy lore in her scientific treatise Philosophical Letters and in fictional texts from Natures Pictures and Poems and Fancies. Though Cavendish was a dedicated materialist, she appropriates theories of magic from early modern science and folklore into her materialist epistemology. As Cavendish draws upon a fusion of early modern conceptions of magic, she creates a radical theory of matter which not only challenges patriarchy and binary oppositions, but also explores the plurality and mystery that can exist within an infinitely complex material world.

  20. OT2_cceccare_5: Peering into the engine of a jet-driven bowshock : TMC1B1

    NASA Astrophysics Data System (ADS)

    Ceccarelli, C.

    2011-09-01

    Jet-driven bowshocks seem to be rather ubiquitous in star-forming regions. If the large-scale bow is commonly observed and its kinematics, the actual engine of the outflow, the Mach disk region where the gas is accelerated, has never been detected until now. Recently, we have found observational evidence of the long-searched engine of outflows in the giant molecular bowshock TMC1B1 together with the driving jet, in Taurus (d=140 pc). which allows Herschel to resolve the cooling region of the shock. We propose to use Herschel to investigate the dynamics and physical structure of TMC1B1, a potential benchmark for jet-driven bowshocks studies.

  1. Neuroanesthesia management of neurosurgery of brain stem tumor requiring neurophysiology monitoring in an iMRI OT setting

    PubMed Central

    Sabbagh, Abdulrahmam J.; Al-Yamany, Mahmoud; Bunyan, Reem F.; Takrouri, Mohamad S. M.; Radwan, Sabry Mohammed

    2009-01-01

    This report describes a rare case of ventrally exophytic pontine glioma describing operative and neuroanesthesia management. The combination of intraoperative neuromonitoring was used. It constituted: Brain stem evoked responses/potentials, Motor EP: recording from cranial nerve supplied muscle, and Sensory EP: Medial/tibial. Excision of the tumor was done with intra-operative magnatic resonance imaging (iMRI), which is considered a new modality. PMID:20532111

  2. Software Supportability Risk Assessment in OT&E (Operational Test and Evaluation): An Evaluation of Risk Methodologies.

    DTIC Science & Technology

    1984-08-31

    DISTRIBUTION: UNIMITED) ELC 0 AUUST 31, M94 Wd/A 8 4 496-TR wwvw WW CORPORATION 1801 RANDOLPH ROAD. S.E * ALSUQUERQUE. NEW MEXICO 87106 *(505) 848-5=0...Road, S.E., Albuquerque, New Mexico , 87106, to the Air Force Operational Test and Evaluation Center, Kirtland Air Force Base, New Mexico , 87117. This...metrics described in section 3.4 should be reported in a storyboard fashion. This technique would act as a summary of the ri.sk assessment process

  3. OT2_eegami_5: Herschel Lensing Survey II: Completing the Herschel Legacy with the HST/MCT CLASH Sample

    NASA Astrophysics Data System (ADS)

    Egami, E.

    2011-09-01

    For deep imaging longward of 100 um, confusion noise sets the fundamental sensitivity limits achievable with Herschel, and these limits cannot be improved by integrating longer. To penetrate through this confusion limit and detect faint high-redshift galaxies, gravitational lensing by massive galaxy clusters offers a very powerful and yet cheap solution. For this reason, our team has been conducting a PACS/SPIRE imaging survey of 44 massive lensing clusters as one of the Herschel Key Programs, "The Herschel Lensing Survey" (PI: Egami, 292.3 hrs). Deep PACS/SPIRE imaging data of massive clusters are quite rich with a variety of information, which allows us to study not only the properties of gravitationally lensed high-redshift galaxies but also those of cluster member galaxies and the intracluster medium through the analysis of the Sunyaev-Zel'dovich effect. In January 2010, a massive HST program targeting powerful lensing clusters was accepted as one of the three multi-cycle treasury (MCT) programs. This program, ``the Cluster Lensing And Supernova survey with Hubble'' (CLASH), has an allocation of 524 orbits, and will obtain deep ACS and WFC3 images of 25 massive galaxy clusters using 16 broad-band filters from near-UV (2250 A) to near-IR (1.6 um). These extensive multi-filter imaging observations will produce high-precision photometric redshifts (sigma/(1+z)<0.02). On average, the program spends 20 orbits per cluster. Considering this enormous investment of HST time, the CLASH program will define the ultimate sample of massive galaxy clusters on which future studies will focus. Here, we propose to obtain deep PACS and SPIRE images for 10 CLASH clusters that still lack such data (the other 15 clusters already have a good Herschel coverage). To fully exploit the combination of the Herschel and HST data, the HLS and CLASH teams are submitting this proposal jointly with the participation of key scientists from both teams.

  4. Learning in a Simulation-OT in Heart Surgery and the Challenges of the Scientification of Work

    ERIC Educational Resources Information Center

    Langemeyer, Ines

    2014-01-01

    Enhancing competency and collaboration has become a salient topic of the professional debate on medical safety issues. The advantages of simulation-based training scenarios for team communication, routines and critical work procedures especially in operation theatres have been vigorously discussed. However, the literature on simulation-based…

  5. XM587E2/XM724 Electronic Time Fuzes: Developmental Test/Operational Test (DT/OT) II Test Phase

    DTIC Science & Technology

    1979-11-01

    XM587E2 and XM724 Electronic Time (ET) Fues. Th. work was iperformed by Honeywell Inc.. Defense Systems Division for Harry Diamond Labor &- Stories...se. Ater leaingthe ontct ingstheVC] funciond popely te auomaic estr o anintemitentbass. he on- tactrins an pa prv deo l anintemitent ontct ue t a lac

  6. Deep optical and radio searches for a quiescent counterpart to the optical transient source OTS 1809+31

    NASA Technical Reports Server (NTRS)

    Ricker, George R.; Mock, Patrick C.; Ajhar, Edward A.; Vanderspek, Roland K.

    1989-01-01

    Hudec (1987) has reported the detection of three bright transient optical images from the same celestial location localized to alpha(1950) = 18 h 9 m 26.29 s + or - 0.03 s, delta (1950) = +31 deg 23 arcmin 19.7 arcsec + or - 0.6 arcsec. This paper reports the result of a deep CCD search in four colors undertaken to find the quiescent counterpart of the optical transients. No source is found at the location of the transients to m(B) = 24.5; however, 18 objects in the vicinity of the reported coordinates which are consistent with the source having a proper motion of 1 arcsec/yr. A search at 6 cm with the VLA revealed no source in the mu less than 1 arcsec/yr circle to a 3 sigma limiting flux of 83 micro-Jy.

  7. OT1_bholwerd_1: New HErschel Multi-wavelength Extragalactic Survey of Edge-on Spirals (NHEMESES)

    NASA Astrophysics Data System (ADS)

    Holwerda, B.

    2010-07-01

    Edge-on spiral galaxies are a unique perspective on the vertical structure of spiral disks, both stars and the iconic dark dustlanes. The thickness of these dustlanes can now be resolved for the first time with Herschel in far-infrared and sub-mm emission. Resolved far-infrared and sub-mm observations of edge-on spirals will impact on several current topics. First and foremost, these Herschel observations will settle whether or not there is a phase change in the vertical structure of the ISM with disk mass. Previously, a dramatic change in dustlane morphology was observed as in massive disks the dust collapses into a thin lane. If this is the case, the vertical balance between turbulence and gravity dictates the ISM structure and consequently star-formation and related phenomena (spiral arms, bars etc.). We specificaly target lower mass nearby edge-ons to complement existing Herschel observations of high-mass edge-on spirals. Secondly, the combined data-set, together with existing Spitzer observations, will drive the generation of spiral disk Spectral Energy Distribution models. These model how dust reprocesses starlight to thermal emission but the dust geometry remains the critical unknown. And thirdly, the observations will provide an accurate and unbiased census of the cold dusty structures occasionally seen extending out of the plane of the disk, when backlit by the stellar disk. The proposed 10.4 hours of PACS and SPIRE observations of low- and intermediate-mass disks complement slated Herschel observations of massive edge-on spirals and existing Spitzer observations in the near- infrared.

  8. OT2_bholwerd_3: New HErschel Multi-wavelength Extragalactic Survey of Edge-on Spirals (NHEMESES)

    NASA Astrophysics Data System (ADS)

    Holwerda, B.

    2011-09-01

    Edge-on spiral galaxies are a unique perspective on the vertical structure of spiral disks, both stars and the iconic dark dustlanes. The thickness of these dustlanes can now be resolved for the first time with Herschel in far-infrared and sub-mm emission. Resolved far-infrared and sub-mm observations of edge-on spirals will impact on several current topics. First and foremost, these Herschel observations will settle whether or not there is a phase change in the vertical structure of the ISM with disk mass. Previously, a dramatic change in dustlane morphology was observed as in massive disks the dust collapses into a thin lane. If this is the case, the vertical balance between turbulence and gravity dictates the ISM structure and consequently star-formation and related phenomena (spiral arms, bars etc.). We specificaly target lower mass nearby edge-ons to complement existing Herschel observations of high-mass edge-on spirals. Secondly, the combined data-set, together with existing Spitzer observations, will drive the generation of spiral disk Spectral Energy Distribution models. These model how dust reprocesses starlight to thermal emission but the dust geometry remains the critical unknown. And thirdly, the observations will provide an accurate and unbiased census of the cold dusty structures occasionally seen extending out of the plane of the disk, when backlit by the stellar disk. We ask for priority one for the remaining 8.9 hours of PACS and SPIRE observations of low- and intermediate-mass disks complement slated Herschel observations of massive edge-on spirals and existing Spitzer observations in the near-infrared.

  9. OT1_hnetzer_1: Herschel study of black hole and galaxy evolution: The z<0.3 QUEST AGN sample.

    NASA Astrophysics Data System (ADS)

    Netzer, H.

    2010-07-01

    We propose 15.6 hours of Herschel time to secure high quality data,over the entire 70-500 micron range, for a group of 27 local, luminous active galactic nuclei (the QUEST AGN sample). The sources represent well the optically selected PG-QSO sample with redshifts up to z=0.3, and have been investigated, in great detail, in almost all other wavelength bands. The new far infrared (FIR) data set will be ideal to study various fundamental questions related to the connection and co-evolution of AGN and their host galaxies. Our previous Spitzer/IRS work on the sample has already revealed a clear relationship between the total AGN luminosity and the star formation rate (SFR) in their hosts. However, the previously undetected FIR sources may be situated in red-and-dead hosts and the Herschel observations can find these objects and allow a direct comparison of their AGN properties, like black hole (BH) mass and accretion rate, with those of the sources with high SFR. The observations will also provide unique information about the "intrinsic infrared AGN spectrum" with consequences to dust properties and distribution in such objects. Our sample is a needed ingredient in any Herschel-based studies that combine FIR-selected (IRAS, Spitzer, Herschel) and optically selected samples with their different biases. Its later comparison with similar high redshift observations will provide invaluable information about the cosmological evolution of AGN and star forming galaxies.

  10. Software Supportability Risk Assessment in OT&E (Operational Test and Evaluation): Measures for a Risk Assessment Model

    DTIC Science & Technology

    1984-09-28

    of the event B is con- sidered to occur with P(B). Benefit (ROWE) a) An axiological concept representing anything received that causes a net...that which is sensed being convertible to an indication; the inqication can be logical, axiological , numer- ical, or probaoi1istic. If

  11. 75 FR 181 - Application for Conversion From: (a) OTS-Regulated, State-Chartered Savings Association to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-04

    ... collection, unless the information collection displays a currently valid OMB control number. As part of the...: December 28, 2009. Ira L. Mills, Paperwork Clearance Officer, Office of Thrift Supervision. [FR Doc....

  12. OT1_bmatthew_4: Testing Planetary Dynamics and Evolutionary History in the HR 8799 Planet/Disc System

    NASA Astrophysics Data System (ADS)

    Matthews, B.

    2010-07-01

    We propose to map the debris disc associated with the multi-planet system HR 8799 in order to constrain the current dynamical state of the planetary system and refine models for dust production in the disc, thereby testing models for the origins of the three known giant planets. Herschel's sensitivity and resolution make it possible to image both the cold planetesimal disc (posited to lie between radii of 90-300 AU) as well as the fainter extended halo (300 - 1000 AU radius) at multiple wavelengths. Direct detection of the edges of the cold belt of dust and an independent measure of the system's inclination will provide critical constraints on models of the planetary orbits within the system, particularly for the outer-most planet for which mass and orbit information can be constrained by simultaneous fits to the planet and disc. The combination of three massive, coeval, and spectroscopically characterizable planets, together with the dust disc, makes this system a "Rosetta Stone" for planet formation studies. The disc is also important for differentiating between planet formation scenarios. Models predict variations in resonance structure for migration versus in situ formation, and multi-wavelength variations in observed structure within Herschel's wavelength range in the case of planetary migration. This proposal is at the very heart of Herschel's top science goal of understanding the mechanisms involved in the formation of stars and planetary bodies. The resolution, sensitivity and multi-wavelength imaging of Herschel are crucial to this program.

  13. OT1_aedge_4: A definitive Herschel study of the most powerful local radio galaxy - Cygnus A

    NASA Astrophysics Data System (ADS)

    Edge, A.

    2010-07-01

    Powerful radio galaxies have played a central role in our understanding of active galaxies over the past five decades. Cygnus-A, the brightest and most nearby FR-II source, has been a "Rosetta Stone" in this study. It appears to have the outward characteristics of a normal radio galaxy but it's proximity allows us to identify the more subtle properties of an obscured quasar. The energy provided by this very active galaxy is sufficient to launch the energetic jets we observe but the transport of the energy to the hotspots is poorly constrained and understood. The growing realisation that AGN directly affect their host galaxy through a direct feedback mechanism throughout the lifetime of the galaxy makes it especially important for the most nearby obscured quasar to be observed with the widest possible spectral coverage. We propose to use Herschel to reveal the heating of the central region and the energetics of the hotspots. We request observations of the atomic cooling lines [OI], [OIII] and [CII] that will allow us to compare the energetics of the ISM in Cygnus A with other local and more distant galaxies.

  14. OT1_jsimon01_1: A Population of Dusty B Stars in the SMC: The First Extragalactic Debris Disks?

    NASA Astrophysics Data System (ADS)

    Simon, J.

    2010-07-01

    Using data from the Spitzer Survey of the SMC, we have discovered a population of 120 main sequence B stars with large 24 micron excesses. Optical spectroscopy and the IRAC SEDs demonstrate that they are not ordinary YSOs or Be stars. We suggest instead that these objects may be debris disks around massive main sequence stars. Confirmation of this hypothesis would provide one of the only ways to study the process of planet formation in a low-metallicity external galaxy. We have measured the mid-IR SED of the dust emission with IRS spectroscopy and determined that both cold and warm dust is present. We now propose PACS photometry at 70 microns to unambiguously separate the dust into its warm (and therefore circumstellar) and cold (possibly interstellar) components. These data will enable us to determine how much of the dust is warm and better constrain the temperature distribution; any targets with substantial amounts of warm dust are almost certainly debris disks. If the B stars do indeed host debris disks, they provide perhaps the only plausible method for constraining planet formation in an external galaxy for the foreseeable future.

  15. Evidence of Cholesterol Accumulated in High Curvature Regions: Implication ot the Curvature Elastic Energy for Lipid Mixtures

    SciTech Connect

    Wang,W.; Yang, L.; Huang, H.

    2007-01-01

    Recent experiments suggested that cholesterol and other lipid components of high negative spontaneous curvature facilitate membrane fusion. This is taken as evidence supporting the stalk-pore model of membrane fusion in which the lipid bilayers go through intermediate structures of high curvature. How do the high-curvature lipid components lower the free energy of the curved structure? Do the high-curvature lipid components modify the average spontaneous curvature of the relevant monolayer, thereby facilitate its bending, or do the lipid components redistribute in the curved structure so as to lower the free energy? This question is fundamental to the curvature elastic energy for lipid mixtures. Here we investigate the lipid distribution in a monolayer of a binary lipid mixture before and after bending, or more precisely in the lamellar, hexagonal, and distorted hexagonal phases. The lipid mixture is composed of 2:1 ratio of brominated di18:0PC and cholesterol. Using a newly developed procedure for the multiwavelength anomalous diffraction method, we are able to isolate the bromine distribution and reconstruct the electron density distribution of the lipid mixture in the three phases. We found that the lipid distribution is homogenous and uniform in the lamellar and hexagonal phases. But in the distorted hexagonal phase, the lipid monolayer has nonuniform curvature, and cholesterol almost entirely concentrates in the high curvature region. This finding demonstrates that the association energies between lipid molecules vary with the curvature of membrane. Thus, lipid components in a mixture may redistribute under conditions of nonuniform curvature, such as in the stalk structure. In such cases, the spontaneous curvature depends on the local lipid composition and the free energy minimum is determined by lipid distribution as well as curvature.

  16. The first N-terminal unprotected (Gly-Aib)n peptide: H-Gly-Aib-Gly-Aib-OtBu.

    PubMed

    Gessmann, Renate; Brückner, Hans; Petratos, Kyriacos

    2015-12-01

    Glycine (Gly) is incorporated in roughly half of all known peptaibiotic (nonribosomally biosynthesized antibiotic peptides of fungal origin) sequences and is the residue with the greatest conformational flexibility. The conformational space of Aib (α-aminoisobutyric acid) is severely restricted by the second methyl group attached to the Cα atom. Most of the crystal structures containing Aib are N-terminal protected. Deprotection of the N- or C-terminus of peptides may alter the hydrogen-bonding scheme and/or the structure and may facilitate crystallization. The structure reported here for glycyl-α-aminoisobutyrylglycyl-α-aminoisobutyric acid tert-butyl ester, C16H30N4O5, describes the first N-terminal-unprotected (Gly-Aib)n peptide. The achiral peptide could form an intramolecular hydrogen bond between the C=O group of Gly1 and the N-H group of Aib4. This hydrogen bond is found in all tetrapeptides and N-terminal-protected tripeptides containing Aib, apart from one exception. In the present work, this hydrogen bond is not observed (N...O = 5.88 Å). Instead, every molecule is hydrogen bonded to six other symmetry-related molecules with a total of eight hydrogen bonds per molecule. The backbone conformation starts in the right-handed helical region (and the left-handed helical region for the inverted molecule) and reverses the screw sense in the last two residues.

  17. [Study of physical-chemical properties ot endodontic sealant Acroseal when different methods of root canal obturation].

    PubMed

    Ivanova, E V; Zubov, S V; Ivanchenko, O N; Poiurovskaia, I Ia; Rusanov, F S

    2009-01-01

    Results of the study of physical-chemical properties of new endodontic sealant Acrosil (Septodent, France) were presented. The results of all used in the experiment tests corresponded with the existing standards. The received data were compared with the corresponding tests of endodontic sealant AH-Plus (Dentsply, DeTrey, Germany) and were analyzed statistically. The comparison showed higher adhesion properties of Acrosil.

  18. Thermobarostability of alpha-chymotrypsin in reversed micelles of aerosol OT in octane solvated by water-glycerol mixtures.

    PubMed

    Rariy, R V; Bec, N; Klyachko, N L; Levashov, A V; Balny, C

    1998-03-05

    Thermostability of alpha-chymotrypsin at normal pressure in reversed micelles depends on both an effective surfactant solvation degree and glycerol content in the system. The difference in alpha-chymotrypsin stability in reversed micelles at various glycerol concentrations [up to 60% (v/v)] was more pronounced at high surfactant degrees of solvation, R >/= 16. After a 1-h incubation at 40 degrees C in "aqueous" reversed micelles (in the absence of glycerol), alpha-chymotrypsin retained only 1% of initial catalytic activity and 10, 22, 59, and 48% residual activity in glycerol-solvated micelles with 20, 30, 50, and 60% (v/v) glycerol, respectively. The explanation of the observed effects is given in the frames of micellar matrix structural order increasing in the presence of glycerol as a water-miscible cosolvent that leads to the decreasing mobility of the alpha-chymotrypsin molecule and, thus the increase of its stability. It was found that glycerol or hydrostatic pressure could be used to stabilize alpha-chymotrypsin in reversed micelles; a lower pressure is necessary to reach a given level of enzyme stability in the presence of glycerol. Copyright 1998 John Wiley & Sons, Inc.

  19. OT2_vkulkarn_3: Star Formation and Molecular Gas in Distant Galaxies: SPIRE Spectroscopy of Quasar Absorption Systems

    NASA Astrophysics Data System (ADS)

    Kulkarni, V.

    2011-09-01

    Absorption line systems in quasar spectra, especially the damped Lyman alpha (DLA) and sub-DLA absorbers, provide excellent venues for directly studying the interstellar medium (ISM) in distant galaxies, selected independently of the galaxy luminosities. DLAs/sub-DLAs provide most of the neutral gas reservoir for star formation at high redshifts. A few especially cold, dusty absorbers have been discovered using radio surveys and the Sloan Digital Sky Survey. These absorbers, far richer in dust/molecules than the general absorber population, give us rare opportunities to probe molecular gas and star formation at high redshift. Unfortunately, very few sub-mm observations exist for these unique quasar absorbers. Here we propose SPIRE spectroscopy of 5 quasars with strong absorbers that appear to have cold/dusty gas. The proposed data will efficiently cover a wide spectral range that is expected to be rich in transitions of many atomic and molecular species (e.g., C I, N II, CH+, CO, 13CO, C18O, H2O) at the absorber redshifts. These transitions will allow us to estimate molecular abundances, and physical conditions of the absorber gas such as temperature and density. Comparisons of these distant absorbers with Milky Way ISM will provide a step toward understanding how ISM evolves with time. The molecular lines will also give constraints on isotopic ratios such as 12CO/13CO, and the cosmic microwave background temperature at the absorber redshifts. Our data will also cover the redshifted [C II] 158 micron emission line, which can help to constrain the star formation rate in the absorber galaxies. The proposed data will thus provide several fresh insights into the stellar and interstellar content of distant galaxies, and pave the way for future ALMA observations. Additionally, the data will provide important constraints on the continuum SEDs of the background quasars. Herschel SPIRE is the only current instrument that can offer the wavelength coverage needed to efficiently observe the lines of interest.

  20. Topographic form of the Coast Ranges of the Cascadia Margin in relation ot coastal uplift rates and plate subduction

    NASA Technical Reports Server (NTRS)

    Kelsey, Harvey M.; Engebretson, David C.; Mitchell, Clifton E.; Ticknor, Robert L.

    1994-01-01

    The Coast Ranges of the Cascadia margin are overriding the subducted Juan de Fuca/Gorda plate. We investigate the extent to which the latitudinal change in attributes related to the subduction process. These attributes include the varibale age of the subducted slab that underlies the Coast Ranges and average vertical crustal velocities of the western margin of the Coast Rnages for two markedly different time periods, the last 45 years and the last 100 kyr. These vertical crustal velocities are computed from the resurveying of highway bech marks and from the present elevation of shore platforms that have been uplifted in the late Quaternary, respectively. Topogarphy of the Coast Ranges is in part a function of the age and bouyancy of the underlying subducted plate. This is evident in the fact that the two highest topographic elements of the Coast Rnages, the Klamath Mountains and the Olympic Mountains, are underlain by youngest subducted oceanic crust. The subducted Blanco Fracture Zone in southernmost Oregon is responsible for an age discontinuity of subducted crust under the Klamath Mountains. The norhtern terminus of hte topographically higher Klamaths is offset to the north relative to the position of the underlying Blanco Fracture Zone, teh offset being in the direction of migration of the farcture zone, as dictated by relative plate motions. Vertical crustal velocities at the coast, derived from becnh mark surveys, are as much as an order of magnitude greater than vertical crustal velocities derived from uplifted shore platforms. This uplift rate discrepancy indicates that strain is accumulating on the plate margin, to be released during the next interplate earthquake. In a latitudinal sense, average Coast Rnage topography is relatively high where bench mark-derived, short-term vertical crustal velocities are highest. Becuase the shore platform vertical crustal velocities reflect longer-term, premanent uplift, we infer that a small percentage of the interseismic strain that accumulates as rapid short-term uplift is not recovered by subduction earthquakes but rather contributes to rock uplift of the Coast Ranges. The conjecture that permanent rock uplift is related to interseismic uplift is consistent with the observation that those segments of the subduction zone subject to greater interseismic uplift rates are at approximately the same latitudes as those segments of the Coast Ranges that have higher magnitudes of rock uplift over the long term.

  1. OT1_mthomp01_1: Confirming a sample of luminous debris disk candidates identified in the Herschel ATLAS

    NASA Astrophysics Data System (ADS)

    Thompson, M.

    2010-07-01

    Debris disks are the remains of planetary system formation, tracing the existence of planetesimal-sized objects in orbit around main sequence stars. Current and planned surveys of debris disks (including the Herschel Key Projects DEBRIS and DUNES) are deep surveys aimed at characterising the typical population of disks and targeted at samples of a few hundred nearby objects. These deep narrow surveys are relatively insensitive to the rarities in the debris disk population, some of which may be luminous and/or massive disks that have undergone recent disruptive collisional events. We have recently shown that the primarily extragalactic Key Project, the Herschel-ATLAS, can be used as a wide and shallow survey of debris disks by combining its excellent optical coverage and statistical techniques more commonly employed to identify galaxies. The combination of Herschel-ATLAS, DEBRIS and DUNES thus forms a powerful nested tier of surveys that will be sensitive to disks across the spectrum from exosolar analogues to rare disks that cannot be inferred from local populations. In this proposal we seek time to image the three candidate disks that we discovered in the Herschel-ATLAS Science Demonstration Phase with PACS so that we may confirm them as true debris disks and model their SEDs to extract mass, temperature and fractional luminosity. We will confirm whether these disk candidates are in fact the most luminous disks yet detected.

  2. OT2_kstape01_1: The Final Four: Completing Herschel's Imaging Legacy for Key Debris Disk Systems

    NASA Astrophysics Data System (ADS)

    Stapelfeldt, K.

    2011-09-01

    Debris disks are the signposts of planetary systems: collisions among asteroidal and cometary parent bodies maintain the observed dust population against losses to radiation pressure and P-R drag. While hundreds of debris disks are known from far-IR excecss emission around main sequence stars, the best- understood systems are the ~20 that are spatially resolved. Disk images establish the size scale of an exoplanetary system. They can reveal central holes, rings, gaps, warps, and asymmetries in the dust distribution which indicate the presence of planetary perturbers. Disk images at different wavelengths are sensitive to dust grains of different sizes, and thus provide a way to trace dust transport and segregation processes. In spring 2011 we discovered large new debris disk in HST coronagraphic images. The new system is an eccentric ring with a sharp inner edge and cleared central zone, and thus is remarkably similar to the classic Fomalhaut debris ring. Spitzer only detected the system at a single wavelength. We propose PACS and SPIRE imaging photometry to fully establish the spatial and spectral properties of this new debris system, and of three other HST-detected debris disks that lack Herschel measurements. Simultaneous modeling of the far-IR images, SEDs, and HST images of these disk will provide important constraints on the physical properties and dynamical state of their constituent dust. Our small program will complete Herschel's legacy dataset for the key subsample of bright disks that are detected in scacttered light,

  3. OT2_lyan_4: Investigate the Physical Nature of An Extraordinarily Far-IR bright Galaxy Discovered by WISE

    NASA Astrophysics Data System (ADS)

    Yan, L.

    2011-09-01

    We request a total of 5.3 hours of Herschel PACS and SPIRE time to investigate the physical nature of an extraordinarily far-IR bright system discovered by the WISE data. This object was first selected to have an extremely red mid-IR SED, very bright at 22micron (38mJy) and not detected at WISE 3.4 and 4.5 micron. At the WISE 12micron position, we found it has IRAS far-IR emission, (600+-59)mJy & (855+-170)mJy at 60 and 100 micron respectively (2' beam). A small 350 micron map, taken with the CSO SHARCII under an exceptionally good weather condition, has detected a 32mJy source at the WISE position. The large discrepancy between fluxes at IRAS 100 micron and CSO 350 micron is intriguing. We propose to clarify the nature of this system --- whether a single or a group of far-IR bright sources --- by utilizing Herschel's high spatial resolution and fast mapping speed. The Herschel photometry, together with the Keck spectra, will allow us to determine the full IR SEDs and the physical parameters such as IR luminositie, SFR and star formation efficiecy. In addition, the deep Keck LRIS spectrum of the galaxy closest to the WISE 12 micron position has found an emission line object at redshift of 0.593, and the Keck NIRC2 K-band Adaptive Optics image shows an extended, disk like galaxy. At z=0.593, the strong IRAS far-IR emission implies very high L(FIR), in the range of (2.1-10)e+12Lsun, with the lower limit set by considering only 1/4 of the IRAS fluxes. We propose to obtain SPIRE FTS spectroscopy to measure [CII]158um line. At this redshift, this line can only be observed by Herschel, and is outside the ALMA wavelength window. With the measured [CII]-to-L(FIR) ratio, we can constraint the molecular gas mass of Source A by utilizing the correlation between [CII]-to-L(FIR) and L(FIR)/M(H2). Even with null detection, our observation will provide meaningful constraint on the ISM properties of this ULIRG.

  4. High-Amplitude, Rapid Photometric Variation of the New Polar Master OT J132104.0+560957.8

    DTIC Science & Technology

    2015-02-05

    the basis of rapid (∼30 min), high-amplitude (∼2 mag) variation. To investigate this classification, we obtained follow-up photometry with a 28-cm...V -band photometry of J1321 with the VATT on 2013 February 7 and on four consecutive nights in 2014, beginning on June 28 and ending on July 1...Additional photometry was obtained with the United States Naval Observatory Flagstaff Station’s 1.3-m telescope on seven nights in 2013 (May 25–28 and June

  5. Hypersonic aeroheating test of space shuttle vehicle: Configuration 3 (model 22 OTS) in the NASA-Ames 3.5-foot hypersonic wind tunnel (IH20), volume 2

    NASA Technical Reports Server (NTRS)

    Kingsland, R. B.; Lockman, W. K.

    1975-01-01

    The model tested was an 0.0175-scale version of the vehicle 3 space shuttle configuration. Temperature measurements were made on the launch configuration, orbiter plus tank, orbiter alone, tank alone, and solid rocket booster (SRB) alone to provide heat transfer data. The test was conducted at free stream Mach numbers of 5.3 and 7.3 and at free stream Reynolds numbers of 1.5, 3.7, 5.0, and 7.0 million per foot. The model was tested at angles of attack from -5 deg to 20 deg and side slip angles of -5 deg and 0 deg.

  6. An investigation of drag reduction fairings on the space shuttle vehicle 5 configuration (model 74-OTS) in the MSFC 14 inch trisonic wind tunnel (FA14)

    NASA Technical Reports Server (NTRS)

    Ramsey, P. E.

    1976-01-01

    An experimental investigation was conducted in the MSFC 14-inch TWT (FA14, TWT 600) to determine the static stability and drag on a 0.004 scale model of the shuttle ascent configuration. The primary objective was to study the possibility of reducing the launch vehicle drag by using Orbiter/ET/SRB fairings, streamlined orbiter fore and aft attach structures, SRB and ET alternative nose configurations, and devices for modifying the flow between the orbiter and ET. The secondary objective was to determine the longitudinal and directional characteristics of the ascent configuration with the most promising of the drag reduction devices installed. Data were obtained for a Mach number range of 0.6 through 4.96 and angles of attack from -5 through 5 degrees at zero degrees side slip angle.

  7. OT2_jpineda_2: Large-scale dynamics and the formation of clouds and stars in the 30 Doradus region of the Large Magellanic Cloud

    NASA Astrophysics Data System (ADS)

    Pineda, J.

    2011-09-01

    Understanding the processes governing the formation of clouds and stars in merging systems is key for the study of how galaxies evolved in the early Universe. The 30 Doradus region in the low-metallicity Large Magellanic Cloud (LMC) is the nearest example of this process, resulting from the interaction between the LMC and the halo of the Milky Way. This makes 30 Doradus the prime laboratory to study these large-scale dynamical processes under conditions that are similar to those at early cosmological times. We propose to use Herschel to obtain a large-scale uniform sampling of this region in [CII] 158um, [NII] 122um and 205um, and [OI] 63um and 146um lines with PACS, and at selected positions in [CII] with HIFI. With this data we will derive the large-scale distribution of the density and pressure of the low-metallicity gas revealing the characteristic signatures of shocked gas. This will then be used to determine the relationships among the diffuse, "dark H2", and dense molecular gas in the 30 Doradus region. We will also derive the electron density distribution of the gas and from this the contribution from ionized gas to the observed [CII] emission. The proposed observations will allow us to study the effect of large-scale gas compression in the multiphase, low-metallicity interstellar medium of 30 Doradus. This information will be valuable for the interpretation of future observations of [CII] in high-redshift galaxies made with ALMA

  8. OT2_rsahai_6: Probing the molecular disk in Y Gem: an AGB star with variable UV emission signifying accretion onto a binary companion

    NASA Astrophysics Data System (ADS)

    Sahai, R.

    2011-09-01

    We propose to observe CO J=6-5 and 9-8 line emission from a cool AGB star, Y Gem, which, in dramatic contrast to most objects in its class, has relatively strong and variable FUV and NUV fluxes - evidence of variable accretion of matter onto an accretion disk in a binary system. We found Y Gem as a UV source serendipitously, while combing the GALEX archive as part of a project to look for hot binary companions to cool AGB stars. This object may represent the earliest phases of an AGB star with a growing accretion disk which will produce collimated jets that are widely believed to sculpt the round circumstellar envelopes of AGB stars into bipolar planetary nebulae. It may evolve into a member of the class of post-AGB objects which show no extended outflows, but only circumbinary disks. HIFI observations of high-J CO lines are needed to probe the warmest and innermost circumstellar regions where the hypothesized accretion disk resides and jet launching may occur. Furthermore, the proposed CO observations, together with our existing CO J=2-1 data, will allow us to accurately constrain the CO excitation temperature, and the optical depths of the CO lines and thus the total mass of the emitting region. The disk or torus mass will provide an important constraint on its formation process (e.g., common envelope evolution or Bondi-Hoyle wind-accretion/ Roche lobe overflow.)

  9. [Characteristics of floor litter and soil arthropod community in different types ot subtropical forest in Ailao Mountain of Yunnan, Southwest China].

    PubMed

    Yang, Zhao; Yang, Xiao-Dong

    2011-11-01

    By using line transect method, an investigation was conducted on the floor litter and soil arthropod community in a mid mountain wet evergreen broad-leaved forest, a mossy dwarf forest, and a Populus bonatii forest in Ailao Mountain of Yunnan in April (dry and hot season), June (rainy season), and December (dry and cold season), 2005. In both dry and rainy seasons, the existing floor litter mass, C storage, and C/N ratio in the three forests all increased in the order of mossy dwarf forest > P. bonatii forest > evergreen broad-leaved forest, but the N storage had less difference. In the floor litter layer of the forests, Acari and Collembola were the dominant groups of soil arthropod community, while Diptera larvae, Coleoptera, ants, and Homoptera were the common groups. The Sorenson coefficients of soil arthropod community in the three forests were extremely great. No significant differences were observed in the soil arthropod density (ind x m(-2)) in the floor litter layer among the three forests, but the relative density (ind x g(-1)) of soil arthropods was higher in the evergreen broad-leaved forest and P. bonatii forest than in the mossy dwarf forest. In the three forests, the density of soil arthropods was significantly higher in dry season than in rainy season, but the Shannon diversity index had less difference. There were significant positive correlations between the existing floor litter mass and the individual density (ind x m(-2)) and dominant groups of soil arthropod communities in dry and hot season (April), but negative correlations between the existing floor litter mass and the relative density (ind x g(-1)) of soil arthropod communities and Acari in dry and cold season (December). The individual densities of Collembola and Coleoptera also had positive correlations with the N storage of the existing floor litter mass in the three forests. It was considered that the floor litter and the development of soil arthropod community in the litter layer of the subtropical forests in Ailao Mountain had a close relation with the vegetation structure of the forests, and the individual density and the diversity of the soil arthropod community were controlled by the floor litter, whereas the environmental factors such as temperature and moisture in the forests also had obvious effects on the seasonal dynamics of the individual density of the soil arthropods.

  10. Wind tunnel test of the 0.019 scale space shuttle integrated vehicle (model 14-OTS) in the CALSPAN 8-foot transonic wind tunnel (IA36), volume 2

    NASA Technical Reports Server (NTRS)

    Hardin, R. B.; Burrows, R. R.

    1975-01-01

    A test is presented which was performed to determine the effect of cold jet gas plumes generated from main propulsion system and solid rocket motor nozzles on: (1) six-component force and moment data, (2) wing static pressures, (3) wing hinge moment, (4) elevon hinge moment, (5) rudder hinge moment, and (6) orbiter MPS nozzle pressure loads. The effects of rudder deflection, nozzle gimbal angle, and plume size were also obtained.

  11. Subject and authorship of records related to the Organization for Tropical Studies (OTS) in BINABITROP, a comprehensive database about Costa Rican biology.

    PubMed

    Monge-Nájera, Julián; Nielsen-Muñoz, Vanessa; Azofeifa-Mora, Ana Beatriz

    2013-06-01

    BINABITROP is a bibliographical database of more than 38000 records about the ecosystems and organisms of Costa Rica. In contrast with commercial databases, such as Web of Knowledge and Scopus, which exclude most of the scientific journals published in tropical countries, BINABITROP is a comprehensive record of knowledge on the tropical ecosystems and organisms of Costa Rica. We analyzed its contents in three sites (La Selva, Palo Verde and Las Cruces) and recorded scientific field, taxonomic group and authorship. We found that most records dealt with ecology and systematics, and that most authors published only one article in the study period (1963-2011). Most research was published in four journals: Biotropica, Revista de Biología Tropical/ International Journal of Tropical Biology and Conservation, Zootaxa and Brenesia. This may be the first study of a such a comprehensive database for any case of tropical biology literature.

  12. Laboratory and outside the laboratory measurements of ginned and ot ginned cotton for fiber micronaire and maturity by portable Near Infrared (NIR) Instruments

    USDA-ARS?s Scientific Manuscript database

    Micronaire is a key cotton quality assessment property, impacting downstream fiber processing and dye consistency. A component of micronaire is fiber maturity (degree of secondary wall development). Historically, micronaire and maturity are measured in a laboratory under tight environmental condit...

  13. Crystallization and preliminary X-ray crystallographic analysis of a conserved domain in plants and prokaryotes from Pyrococcus horikoshii OT3

    SciTech Connect

    Lin, Linyen; Nakano, Hiroaki; Uchiyama, Susumu; Fujimoto, Satoru; Matsunaga, Sachihiro; Nakamura, Shota; Kobayashi, Yuji; Ohkubo, Tadayasu; Fukui, Kiichi

    2005-04-01

    A plant- and prokaryote-conserved domain (PPC) has been crystallized. The crystal diffracted to 1.7 Å resolution and belonged to space group P6{sub 3}22. A plant- and prokaryote-conserved domain (PPC) has previously been found in AT-hook motif nuclear localized protein 1 (AHL1) localized in the nuclear matrix of Arabidopsis thaliana (AtAHL1). AtAHL1 has a DNA-binding function. Mutation analyses of AtAHL1 has previously revealed that the hydrophobic region of the PPC domain is essential for its nuclear localization. In this study, the PPC of the hyperthermophilic archaebacterium Pyrococcus horikoshii (PhPPC) was crystallized using the hanging-drop vapour-diffusion method. The crystals belonged to the hexagonal space group P6{sub 3}22, with unit-cell parameters a = b = 53.69, c = 159.2 Å. Data were obtained at 100 K, with diffraction being observed to a resolution of 1.7 Å. A complete data set from crystals of the SeMet-substituted protein was also obtained.

  14. Treatability Study in Support of Intrinsic Remediation for Site OT 24 at MacDill Air Force Base, Florida. Volume 2

    DTIC Science & Technology

    1997-01-01

    RECORD STABIUZED WATER LEVEL FEET -MO W O A M M. -( S iT t -T r.L TOTAL MONITORING POINT DEPTH 5.5 FEET Intrtnslc Remedistlon TS 0 BLOW DATUM. MacDill...ELEVATION 1’ -Y t., , GROUNO SURFACE ELEVATION ’I, J, DATUM FOR WATER LEVEL MEASUREMENT - A - (S’ SCREEN DIAMLMR & MATERIAL \\ý" . _ . A ,. SLOT SIZE O.c RISFR...Time (Start): I 11 Water Level : Total Depth of Wellt Water Characteristics Color (, 5c14 " -- Clear Odor: None A Moderate Strong Any Films or Immiscible

  15. Aerodynamic results of wind tunnel separation tests on a 0.01-scale model (32-OTS) space shuttle integrated vehicle in the AEDC-VKF-SWTA (IA57)

    NASA Technical Reports Server (NTRS)

    Daileda, J. J.

    1974-01-01

    The integrated space shuttle vehicle was tested to determine proximity force and moment data for the orbiter/external tank and solid rocket booster (SRB) with and without separation rockets firing for both single and dual booster runs. Data were obtained at points t = 0 sec, t = 1.25 sec, and t = 2 sec on the nominal SRB separation trajectory.

  16. Fragmentation of the lamellae and fractionation of polymer coils upon mixing poly(dimethylacrylamide) with the lamellar phase of aerosol OT in water.

    PubMed

    Pacios, Isabel E; Renamayor, Carmen S; Horta, Arturo; Lindman, Björn; Thuresson, Krister

    2005-12-22

    The lamellar mesophase formed by surfactant 1,4-bis(2-ethylhexyl) sodium sulfosuccinate (AOT) in deuterated water is mixed with poly(dimethylacrylamide) (PDMAA) polymers of low molecular weight (Mn= (2-20) x 10(3)). The mixtures separate into microphases (lamellar plus isotropic polymer solution). Their microstructures are studied by microscopy, small-angle X-ray scattering (SAXS), and deuterium NMR (2H NMR). According to SAXS, the lamellar phase fractionates the molecular weight distribution of the polymer, by dissolving only chains with coil sizes smaller than the thickness of the water layers between lamellae, and keeping larger chains segregated from the lamellar phase. The fraction of polymer that is segregated from the lamellar phase grows with Mn of the polymer. In 2H NMR, there are two signals, a quadrupolar doublet (water molecules hydrating the anisotropic lamellar phase contribute to this doublet) and a singlet (water molecules in the isotropic polymer solution contribute to this singlet). These two signals are deconvoluted to analyze the phases. Mixing with the polymer produces the partial dispersion of the lamellar phase into small fragments (microcrystallites). The structure of these microcrystallites is such that they conserve the regular long period spacing of the macrophase, and are thus identified in SAXS, but they are smaller than the minimum size required to produce quadrupolar splitting (about 4 microm), and therefore, in 2H NMR, they contribute to the singlet. 2H NMR can thus not distinguish between small microcrystallites and an isotropic polymer solution segregated from the lamellar phase; instead small microcrystallites are detected as an apparent increase of the isotropic solution. The degree of dispersion produced by the polymer in the lamellar phase is correlated with the degree of segregation that the polymer suffers. Thus, much greater dispersion into microcrystallites is produced by the higher Mn polymers than by the lower Mn polymers (in the range covered by the present samples, although with a much higher molecular weight sample (3 x 10(6)) that is totally segregated no such microcrystallites were detected).

  17. OT1_sserje01_1: THE HERSCHEL-AKARI NEP DEEP SURVEY: the cosmological history of stellar mass assembly and black hole accretion

    NASA Astrophysics Data System (ADS)

    Serjeant, S.

    2010-07-01

    We propose a far-IR and submm mapping survey of the premier AKARI deep field in the North Ecliptic Pole, in PACS/SPIRE parallel mode. This is the only major deep infrared field not yet covered by Herschel guaranteed or open time key projects. The outstanding and unparalleled continuous mid-IR photometric coverage from AKARI, far better than equivalent Spitzer surveys, enables a wide range of galaxy evolution diagnostics unachievable in any other survey field (including Herschel HerMES/PEP fields), by spanning the wavelengths of redshifted PAH and silicate features and the peak energy output of AGN dust tori. The investment by AKARI in the NEP represents ~10 percent of the entire pointed observations available throughout the lifetime of AKARI. Our proposal remedies the remarkable omission from Herschel's legacy surveys of the premier extragalactic deep field from another IR space telescope. We will simultaneously identify and find photometric redshifts for the Herschel point source population, make stacking analysis detections of the galaxies which dominate the submm extragalactic background light as a function of redshift, determine the bolometric power outputs of the galaxies that dominate the submm background, compare the UV/optical/mid-IR continuum/PAH/far-IR/submm/radio star formation rate estimator in the most comprehensive IR survey data set to date, and track the coupled stellar mass assembly and black hole accretion throughout most of the history of the Universe.

  18. 12 CFR 502.27 - How does OTS determine the risk/complexity component for a savings and loan holding company?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... risk, noncomplex holding company); Category II (complex or high risk holding company); or Category III... Holding Company Handbook. (3) A conglomerate is a holding company that: (i) is one of the most complex or... made up of a number of different companies or legal enterprises that offer products from more than...

  19. 12 CFR 502.27 - How does OTS determine the risk/complexity component for a savings and loan holding company?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... risk, noncomplex holding company); Category II (complex or high risk holding company); or Category III... Holding Company Handbook. (3) A conglomerate is a holding company that: (i) is one of the most complex or... made up of a number of different companies or legal enterprises that offer products from more than...

  20. OT2_lolmi_3: The physical and chemical state of high-mass pre- and proto-stellar cores identified by the Hi-GAL survey

    NASA Astrophysics Data System (ADS)

    Olmi, L.

    2011-09-01

    We propose to investigate the physical, chemical and dynamical properties of a sample of newly found high-mass pre- and proto-stellar cores identified by the ``Herschel infrared GALactic Plane Survey'' (Hi-GAL; Molinari et al. 2010). We will perform observations of the o-NH3(1_0-0_0) line (and, simultaneously, also of the o-H2O(1_10-1_01) transition) that will allow us to identify both similarities and differences between the physical and chemical conditions before and after the formation of a warm/hot source inside the dusty core identified in the SPIRE/PACS maps. Hence, these observations will improve our knowledge of the earliest phases in the evolution of high-mass stars. We will also attempt the detection of the NH(1-0) line towards a smaller sample of sources, in order to improve our knowledge of the N-chemistry during early high-mass star formation.

  1. GENERAL REGULARITIES OF FORMATION OF CRYSTAL STRUCTURES OF ELEMENTS DEPENDING ON ELECTRON STRUCTURE OF ATOMS (OBSHCHILE ZAKONOMERNOSTI OBRAZOVANIYA KRISTALLICHESKIKH STRUKTUR ELEMENTOV V ZAVISIMOSTI OT ELEKTRONNOGO STROENIYA ATOMOV),

    DTIC Science & Technology

    A table is given showing the dependence of crystalline structures of elements on the number of electrons in the incompleted electronic subshells of...its atoms. The conclusion is drawn that the types of crystalline structures of the elements depend on the configuration of the outer electronic...subshells acquired by the atoms prior to crystallization. Crystalline structures of elements not governed by the 8 - N rule are determined by one or both

  2. 33 CFR 150.445 - When is oil in a single point mooring-oil transfer system (SPM-OTS) displaced with water?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... the pipeline end manifold must be closed whenever: (1) A storm warning forecasts weather conditions... vessel is about to depart the SPM because of storm conditions; or (3) The SPM is not scheduled for use...

  3. 33 CFR 150.445 - When is oil in a single point mooring-oil transfer system (SPM-OTS) displaced with water?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... the pipeline end manifold must be closed whenever: (1) A storm warning forecasts weather conditions... vessel is about to depart the SPM because of storm conditions; or (3) The SPM is not scheduled for use...

  4. 33 CFR 150.445 - When is oil in a single point mooring-oil transfer system (SPM-OTS) displaced with water?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... the pipeline end manifold must be closed whenever: (1) A storm warning forecasts weather conditions... vessel is about to depart the SPM because of storm conditions; or (3) The SPM is not scheduled for use...

  5. 33 CFR 150.445 - When is oil in a single point mooring-oil transfer system (SPM-OTS) displaced with water?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the pipeline end manifold must be closed whenever: (1) A storm warning forecasts weather conditions... vessel is about to depart the SPM because of storm conditions; or (3) The SPM is not scheduled for use...

  6. INDUCTION OF GENOTOXIC DAMAGE IS NOT HIGHLY CORRELATED WITH THE ABILITY OT METHYLATE ARSENITE IN VITRO IN THE LEUKOCYTES OF 4 MAMMALIAN SPECIES

    EPA Science Inventory


    Abstract

    Arsenic is a natural drinking water contaminant that impacts the health of large populations of people throughout the world; however, the mode or mechanism by which arsenic induces cancer is unclear. In a series of in vitro studies, we exposed leukocytes from...

  7. The Influence of Hydrologic Conditions on the Distribution of Baleen Whales in the Antarctic (Raspredelenie Usatykh Kitov v Anarktike v Zabisimosti ot Gidrologicheskikh Uslovii),

    DTIC Science & Technology

    where a semistationary cyclonic system coincides with plankton rich waters upwelling from great depths. Whales locate these feeding grounds through...growth. They also travel parallel to isohalines to remain in the feeding grounds. (Author)

  8. INTERACTION ANALYSES OF BINARY MIXTURES OF CARCINOGENIC PAHS USING MORPHOLOGICAL CELL TRANSFORMATION OF C3H1OT1/2CL8 MOUSE EMBRYO FIBROBLASTS IN CULTURE.

    EPA Science Inventory

    Studies of defined mixtures of carcinogenic polycyclic aromatic hydrocarbons (PAH) have shown three major categories of interactions: antagonism, synergism, and additivity depending on the biological model, tissue, route of exposure, and specific PAH. To understand the bases of t...

  9. Versatile, sensitive liquid chromatography mass spectrometry – Implementation of 10 μm OT columns suitable for small molecules, peptides and proteins

    PubMed Central

    Vehus, T.; Roberg-Larsen, H.; Waaler, J.; Aslaksen, S.; Krauss, S.; Wilson, S. R.; Lundanes, E.

    2016-01-01

    We have designed a versatile and sensitive liquid chromatographic (LC) system, featuring a monolithic trap column and a very narrow (10 μm ID) fused silica open tubular liquid chromatography (OTLC) separation column functionalized with C18-groups, for separating a wide range of molecules (from small metabolites to intact proteins). Compared to today’s capillary/nanoLC approaches, our system provides significantly enhanced sensitivity (up to several orders) with matching or improved separation efficiency, and highly repeatable chromatographic performance. The chemical properties of the trap column and the analytical column were fine-tuned to obtain practical sample loading capacities (above 2 μg), an earlier bottleneck of OTLC. Using the OTLC system (combined with Orbitrap mass spectrometry), we could perform targeted metabolomics of sub-μg amounts of exosomes with 25 attogram detection limit of a breast cancer-related hydroxylated cholesterol. With the same set-up, sensitive bottom-up proteomics (targeted and untargeted) was possible, and high-resolving intact protein analysis. In contrast to state-of-the-art packed columns, our platform performs chromatography with very little dilution and is “fit-for-all”, well suited for comprehensive analysis of limited samples, and has potential as a tool for challenges in diagnostics. PMID:27897190

  10. Expression, purification, crystallization and preliminary X-ray analysis of the KaiC-like protein PH0187 from the hyperthermophilic archaeon Pyrococcus horikoshii OT3

    PubMed Central

    Kang, Hee-Jin; Kubota, Keiko; Miyazono, Ken-ichi; Tanokura, Masaru

    2011-01-01

    KaiC is the central protein in the circadian rhythm in cyanobacteria. The 28 kDa KaiC-like protein PH0187 from the hyperthermophilic archaeon Pyrococcus horikoshii was expressed in Escherichia coli, purified and crystallized using the sitting-drop vapour-diffusion method at 293 K. Crystals of PH0187 were obtained using a reservoir solution consisting of 1.0 M ammonium phosphate monobasic and 0.1 M sodium citrate tribasic pH 5.3 (the final pH value of the reservoir solution was 4.8) and diffracted X-rays to 2.75 Å resolution. The crystal of PH0187 belonged to space group P6322, with unit-cell parameters a = b = 239.1, c = 106.5 Å. The crystal contained four PH0187 molecules in the asymmetric unit. PMID:21206047

  11. Software Supportability Risk Assessment in OT&E (Operational Test and Evaluation): Literature Review, Current Research Review, and Data Base Assemblage.

    DTIC Science & Technology

    1984-09-28

    used under stated conditions. Axiology (ROWE) The study of the nature of types and criteria of values and 3f ialue judgements, especially in ethics...ROWE) The observable manifestations of performance. Benefit (ROWE) a) An axiological concept representing anything received that causes a net...can be logical, axiological , numer- ical, or probabilistic. If probabilistic, it is empirical and subjective. b) Comparable to some unit designated as

  12. OT2_tdiazsan_1: Size is Not Everything: A PACS Emission Line Study of the Most Compact Infrared-luminous Galaxies

    NASA Astrophysics Data System (ADS)

    Díaz-Santos, T.

    2011-09-01

    Recent results based on far-infrared (IR) data obtained with Herschel strongly suggest the existence of two modes of star formation that apply to low and high-redshift galaxies: a quiescent mode for disks (or main-sequence galaxies) and a starburst mode probably associated with more efficient nuclear, compact star formation. This dichotomy implies that the properties of the inter stellar medium (ISM) in these two types of systems must be substantially different. We have used the mid- to far-IR colors of galaxies as a proxy for their compactness to select a sample of local, compact luminous IR galaxies ((U)LIRGs; LIR >= 10^11 Lsun) from the IRAS 12-micron sample. Our sample of 73 compact (U)LIRGs includes both Seyfert galaxies as well as purely star-forming systems, and therefore is not biased towards active galaxies only. We will observe the key far-IR [CII]158, [OI]63, and [OIII]88 micron emission lines with Herschel/PACS and use models of photo-dissociation regions (PDRs), shocks, X-ray dissociation regions (XDRs), and dusty AGNs to derive the main physical parameters of the ISM in this important class of systems, which are not being targeted by any Herschel project. Our proposed galaxy sample bridges the gap between other studies focused on the analysis of local galaxies with a range of IR luminosities, mid- to far-IR colors, or more spatially extended IR emission, providing a wider view of the star formation and nuclear activity in local IR-bright galaxies in extreme environments, and thus adding a significant contribution to the Herschel legacy. The total time requested for achieving this goal is 89.8 hours.

  13. INDUCTION OF GENOTOXIC DAMAGE IS NOT HIGHLY CORRELATED WITH THE ABILITY OT METHYLATE ARSENITE IN VITRO IN THE LEUKOCYTES OF 4 MAMMALIAN SPECIES

    EPA Science Inventory


    Abstract

    Arsenic is a natural drinking water contaminant that impacts the health of large populations of people throughout the world; however, the mode or mechanism by which arsenic induces cancer is unclear. In a series of in vitro studies, we exposed leukocytes from...

  14. MASTER-SAAO follow-up to Fermi-LAT detection of FSRQ PKS B1035-281 activity. And OTs

    NASA Astrophysics Data System (ADS)

    Lipunov, V. M.; Buckley, D. A. H.; Shurpakov, S.; Balanutsa, P.; Gress, O.; Gorbovskoy, E.; Tiurina, N.; Kuznetsov, A.; Vladimirov, V.; Kornilov, V.; Vlasenko, D.; Gorbunov, I.; Popova, E.; Kuvshinov, D.; Kniazev, A.; Potter, S. B.; Kotze, M.; Rebolo, R.; Ricart, M. Serra; Israelian, G.; Lodieu, N.

    2016-02-01

    MASTER-SAAO auto-detection system (Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 349171 ) detected the brightening of the FSRQ PKS B1035-281 (RA=10 37 42.457 -28 23 04.11) during inspection of Fermi-LAT Detection of its unusual hard spectrum (Carpenter et al., ATEL #8740).

  15. OT2_rivison_2: Characterising the ISM of bright, lensed star-forming galaxies across cosmic time with the SPIRE FTS

    NASA Astrophysics Data System (ADS)

    Ivison, R.

    2011-09-01

    We have shown that SPIRE is capable of exploring high-redshift galaxies spectroscopically, provided those galaxies are sufficiently bright. Here, we propose to exploit its wide wavelength coverage to study the powerful diagnostic rest-frame FIR cooling lines from a sample of 48 bright, lensed - but intrinsically typical - submm galaxies (SMGs). Our targets span 1 < z < 3.1 and 11.5 < log L(FIR) < 13.5, and are selected from panoramic Herschel imaging surveys that are uniquely capable of providing a large, reliable sample at S(350um) > 200mJy, with excellent ancillary data. We will detect or place sensitive limits on key atomic and ionic cooling lines, e.g. [C II], [O I], [O III], and combine these with ground-based observations of 12CO, 13CO, C I and dense-gas tracers to perform a detailed analysis of their ISM and thence understand their energetics and temporal evolution. Using these data we will: 1) empirically constrain the interplay between gas cooling and heating in IR galaxies, mapping the evolution of the star-formation efficiency, exploiting our large sample to separate dependencies on L(FIR) and z, and thereby establishing fundamental relationships for the IR galaxy population; 2) conclusively address the issue of the contribution of AGN to IR galaxies; 3) coadd spectra in the rest frame to delve up to sqrt(48)x deeper than an individual spectrum, to confirm/quantify the signature of powerful feedback via OH molecular outflows, and add powerful diagnostics, e.g. H2O, [O I] and high-J lines, allowing a complete characterisation of the entire FIR spectrum. Goals 1 and 3 drive the requirement for a sample of 48 SMGs. All our goals require Herschel and cannot be addressed by other facilities. We stress that the scientific legacy of ISO and Spitzer has in large part been based on the wealth of data in their spectroscopic archives and the same will likely be true for Herschel.

  16. OT1_rivison_1: Characterising the ISM of bright, lensed star-forming galaxies across cosmic time with the SPIRE FTS

    NASA Astrophysics Data System (ADS)

    Ivison, R.

    2010-07-01

    We have shown that Herschel is capable of exploring high-redshift galaxies spectroscopically, provided those galaxies are sufficiently bright. Here, we propose to exploit the wide wavelength coverage of the SPIRE FTS to study the powerful diagnostic rest-frame FIR cooling lines from a unique and complete sample of 25 bright, gravitationally-lensed - but intrinsically typical - submm galaxies (SMGs). We can thus perform the first detailed analysis of their ISM, tracing their density structure and searching for variations in line strengths compared to local counterparts. Our targets span 1 < z < 3.1 (where [C II] is not accessible to ALMA) and a good range of L(FIR) (12 < log L(FIR) < 13.5), and are selected from panoramic Herschel imaging surveys that are uniquely capable of providing a large, reliable sample at S(350um) > 200mJy, with excellent ancillary data. We will detect or place sensitive limits on the key atomic cooling lines, e.g. [C II], [O I], [O III], and combine these with ground-based observations of 12CO, 13CO, C I and dense-gas tracers to model their ISM and thence understand their energetics and evolution. Using these data we will: 1) map the evolution of the gas content as a function of redshift, via the sensitivity of [C II]/L(FIR) to M(H2); 2) search for changes in the properties of the star-forming gas as a function of redshift and L(FIR); 3) coadd the spectra in the rest frame to delve up to 5x deeper still, to search for faint lines, e.g. H2O and [O I]145.5, allowing a complete characterisation of the average emission; 4) conclusively address the issue of the contribution of AGN to the immense luminosities of submm galaxies. Goals 1-3 drive the requirement for a sample of 25 SMGs. All our goals require Herschel and cannot be addressed by other facilities. We stress that the scientific legacy of ISO and Spitzer has in large part been based on the wealth of data in their spectroscopic archives and the same is likely to be true for Herschel.

  17. OT2_eibar_1: A detailed anaysis of the [CII] line emission for a large sample of star-forming galaxies at z<0.2

    NASA Astrophysics Data System (ADS)

    Ibar, E.

    2011-09-01

    We propose to exploit the spectroscopic capabilities of PACS to describe the [C II] line emission in a unique and comprehensive sample of star-forming galaxies selected from the wide-field, parallel PACS+SPIRE H-ATLAS imaging survey. The sample has exquisite optical spectra from GAMA and SDSS, allowing us to: [1] describe [C II] line as a function of dust and stellar mass, metallicity, extinction, dust temperature, and many other physical parameters; [2] identify the parameters controlling the behaviour of [CII]/L(FIR) at log L(FIR)>11; [3] calibrate [CII] as a star-formation indicator [exploiting our accurate L(FIR) and L(Halpha)] and determine the range over which it is valid. [CII] is potentially an unrivalled tracer of the total gas mass in galaxies (in theory better than CO), and it is therefore an increasingly important observable, e.g. for upcoming ALMA observations of distant galaxies. Our study will become the benchmark for the interpretation of high-z observations, with a legacy value that will survive well into the SPICA era. Some of the key advantages of this proposal over previous Herschel studies such as SHINING and HerCULES are: - we cover 10.2 < log L(FIR) < 11.5 and are unbiased towards powerful ULIRGs with complex merger morphologies; - our sample is selected blindly from H-ATLAS rather than from IRAS, and thus allows exploration of comprehensive parameter space and is much less biased towards galaxies with warm dust emission; - we know the spatial extent of the galaxies, allowing reliable flux measurements via a single pointing within 10 min/target. We can thus achieve our goals in a systematic fashion, maximising the parameter space for the diagnostics of interest. We stress that the scientific legacy of ISO and Spitzer has in large part been based on the wealth of data in their spectroscopic archives and the same will likely be true for Herschel.

  18. [LONG-TERM RESULTS OT SURGICAL ABLATION OF LEFT ATRIAL GANGLIONAR PLEXUS IN PATIENTS WITH CORONARY HEART DISEASE AND ATRIAL FIBRILLATION].

    PubMed

    Chernyavsky, A M; Rakhmonov, S S; Kareva, Yu E; Pak, I A

    2015-01-01

    We evaluated long-term results of epicardial radio-frequency ablation of anatomical zones of left atrial ganglionar plexuses (GP) during aortocoronary bypass surgery in patients with coronary heart disease and atrial fibrillation (AF). In 2010-2012, radio-frequency ablation of GP was performed in 92 patients with AF. The patients were divided into 3 groups depending on the form of AF. Group 1 comprised patients with paroxysmal AF, group 2 with persistent AF, group 3 with long-standing persistent AF. Mean duration of observation was 14.4 ± 9.6 months. Radiofrequency ablation of GP anatomical zones combined with aortocoronary bypass surgery markedly improved the clinical and functional conditions of the patients and allowed to preserve the sinus rhythm for a long period in 78.6% and 39% of them presenting with paroxysmal and long-standing paroxysmal AF respectively.

  19. Method of Transfer from Logical Schemes of Algorithms to Boolean Functions Ot Logicheskikh Skhem Algoritmov K Bulevym Funktsiyam<

    NASA Technical Reports Server (NTRS)

    Dyachenko, V. F.

    1964-01-01

    The author discusses a method for obtaining the Boolean functions describing the structure of a control circuit by means of AS operators whose sequence of operations is given in the form of a logical scheme or matrix scheme for an algorithm. An example of AS synthesis is given.

  20. OT2_jforbric_3: Probing short-term far-infrared variability of protostars and exploring afterglows of X-ray disk heating

    NASA Astrophysics Data System (ADS)

    Forbrich, J.

    2011-09-01

    Recent studies have shown that there is a surprising amount of variability on many timescales in the mid-infrared emission of young stellar objects (YSOs). Especially on short timescales of minutes to hours, mid- and particularly far-infrared variability is currently almost entirely unexplored. While such variability is probing circumstellar disks and envelopes, it is linked to physical processes on the central object. Already the earliest evolutionary stages of YSOs are also strong X-ray emitters, and one important aspect is the heating and possible eventual dispersal of circumstellar disks due to X-ray emission. Even though very important for the understanding of planet formation, this process is poorly understood. The Herschel Space Observatory offers the last possibility for the foreseeable future to explore these processes in more detail and learn about disk heating and explore the occurrence of short-term variability. Here, we propose to do both by repeated observations of the extensively studied nearby Coronet cluster in the CrA star-forming region. Five epochs of near-simultaneous XMM-Newton and Herschel observations, each about 1.5h in duration and spaced by timescales of days to weeks, are meant to explore the short-term variability and link it to the more frequently studied variability on longer timescales. During each epoch, the cluster is mapped 18 times with Herschel. The Coronet has been chosen for having YSOs that can be detected at high S/N in short periods of time while not being too crowded for the angular resolution of both observatories. By exploring far-infrared variability on timescales of several minutes to days and weeks as well as disk heating by protostellar X-ray emission, these short observations will have a unique legacy value.

  1. Treatability Study in Support of Intrinsic Remediation for Site OT 24 at MacDill Air Force Base, Florida. Volume 1

    DTIC Science & Technology

    1997-01-01

    years (calendar year 2016) without the implementation of an engineered remedial action. If a source removal technology such as in situ bioventing is...10 6.3.2 Alternative 2-- Bioventing /Biosparging in Source Area, Intrinsic Remediation, and Institutional Controls with Long-Term Groundwater Monitoring...6-16 6.3.3 Alternative 3--Groundwater Extraction, Bioventing /Biosparging in

  2. OT2_mdickins_1: Herschel+CANDELS: Unraveling the physical processes that regulate star formation and AGN activity in ordinary galaxies at z=2

    NASA Astrophysics Data System (ADS)

    Dickinson, M.

    2011-09-01

    The deepest Herschel surveys have established a distinction between steady "main sequence" star formation, whose rate is closely tied to galaxy mass at a given redshift, and elevated starburst activity in ordinary, L*(IR) galaxies at z > 1.5. They have also shown that supermassive black hole growth occurs mainly through secular processes in these main sequence galaxies, and have revealed otherwise obscured AGN missed by the deepest X-ray surveys. However, the physical processes that trigger starbursts, and the relation between star formation, AGN activity, and the structural properties of galaxies at this peak era of galaxy growth, are far from clear. We propose a survey to address these questions by measuring far-infrared luminosities and star formation rates for a large sample of high redshift galaxies with deep, high-resolution near-infrared imaging from the CANDELS HST WFC3 Treasury program. Herschel PACS and SPIRE observations deep enough to detect 700+ L*(IR) galaxies at z > 1.5 will be obtained for the five CANDELS fields and correlated with the detailed morphological and structural properties that only HST/WFC3 imaging can provide. We will establish whether interactions and mergers drive starburst activity, and examine their relevance for fueling AGN activity. The improved statistics will allow a definitive measure of the space density of L*(IR) galaxies at z=2, a basic (and currently very uncertain) demographic quantity for the history of cosmic star formation. The survey will provide a legacy of targets for detailed investigation with ALMA, tripling (beyond GOODS-South alone) the number of ALMA-accessible fields with the deepest Herschel data.

  3. Job Analysis Techniques for Restructuring Health Manpower Education and Training in the Navy Medical Department. Attachment 10. PT/OT QPCB Task Sort for Physical and Occupational Therapy.

    ERIC Educational Resources Information Center

    Technomics, Inc., McLean, VA.

    This publication is Attachment 10 of a set of 16 computer listed QPCB task sorts, by career level, for the entire Hospital Corps and Dental Technician fields. Statistical data are presented in tabular form for a detailed listing of job duties in physical and occupational therapy. (BT)

  4. OT2_mthomp01_2: Confirming a sample of massive and luminous debris disks identified in the Herschel-ATLAS

    NASA Astrophysics Data System (ADS)

    Thompson, M.

    2011-09-01

    Debris disks are the remains of planetary system formation, tracing the existence of planetesimal-sized objects in orbit around main sequence stars. Current and planned surveys of debris disks (including the Herschel Key Projects DEBRIS and DUNES) are deep surveys aimed at characterising the typical population of disks and targeted at samples of a few hundred nearby objects. These deep narrow surveys are relatively insensitive to the rarities in the debris disk population, some of which may be luminous and/or massive disks that have undergone recent disruptive collisional events. We have recently shown that the primarily extragalactic Key Project, the Herschel-ATLAS, can be used as a wide and shallow survey of debris disks by combining its excellent optical coverage and statistical techniques more commonly employed to identify galaxies. The combination of Herschel-ATLAS, DEBRIS and DUNES thus forms a powerful nested tier of surveys that will be sensitive to disks across the spectrum from exosolar analogues to rare disks that cannot be inferred from local populations. In this proposal we seek time to image 23 candidate disks that we have discovered in the Herschel-ATLAS with PACS so that we may confirm them as true debris disks and model their SEDs to extract mass, temperature and fractional luminosity. We will confirm whether these disk candidates are in fact the most luminous disks yet detected.

  5. Space shuttle launch vehicle (13 P-OTS) strut support interference effects study in the Rockwell International 7- by 7-foot trisonic wind tunnel (IA68)

    NASA Technical Reports Server (NTRS)

    Rogge, R. L.

    1974-01-01

    Strut support interference investigations were conducted on an 0.004-(-) scale representation of the space shuttle launch vehicle in order to determine transonic and supersonic model support interference effects for use in a future exhaust plume effects study. Strut configurations were also tested. Orbiter, external tank, and solid rocket booster pressures were recorded at Mach numbers 0.9, 1.2, 1.5, and 2.0. Angle of attack and angle of sideslip were varied between plus or minus 4 degrees in 2 degree increments. Parametric variations consisted only of the strut configurations.

  6. Hypersonic aeroheating test of space shuttle vehicle configuration 3 (model 22-OTS) in the NASA-Ames 3.5-foot hypersonic wind tunnel (IH20), volume 1

    NASA Technical Reports Server (NTRS)

    Kingsland, R. B.; Lockman, W. K.

    1975-01-01

    The results of hypersonic wind tunnel testing of an 0.0175 scale version of the vehicle 3 space shuttle configuration are presented. Temperature measurements were made on the launch configuration, orbiter plus tank, orbiter alone, tank alone, and solid rocket booster alone to provide heat transfer data. The test was conducted at free-stream Mach numbers of 5.3 and 7.3 and at free-stream Reynolds numbers of 1.5 million, 3.7 million, 5.0 million, and 7.0 million per foot. The model was tested at angles of attack from -5 deg to 20 deg and side slip angles of -5 deg and 0 deg.

  7. OT1_pharve01_3: The Auriga-California Molecular Cloud: A Massive Nearby Cloud With Powerful Diagnostics For Early Stages of Star Formation

    NASA Astrophysics Data System (ADS)

    Harvey, P.

    2010-07-01

    We propose to map the Auriga-California Molecular Cloud (AMC) with the same observing parameters as being used for the rest of the clouds in the Gould Belt by the Herschel GT team conducting that program. The AMC was not included in that program BUT is extremely important as a counterpoint to the Orion Molecular Cloud (OMC) because it is as large and massive as the OMC but has a factor of 10 lower level of star formation, most of which is concentrated at the southeast end near the LkHalpha 101 cluster. We already have complete Spitzer survey data on this cloud and are in the process of obtaining JCMT line and continuum survey observations. The OMC has informed our understanding of star clusters and massive star formation. It is essential, however, to test that understanding by observing other massive clouds with differing levels of star formation. The combination of Herschel data with our existing Spitzer and molecular line data is vital to understand the physical reasons underlying the large differences in star formation between these two regions. Herschel's combination of angular resolution and 5-band imaging for dust temperature and emissivity measurements permit a uniquely high level of analysis of the far-IR emission from the AMC and comparison with the OMC.

  8. Investigation of space shuttle launch vehicle external tank nose configuration effects (model 67-OTS) in the Rockwell International 7 by 7 foot trisonic wind tunnel (IA69)

    NASA Technical Reports Server (NTRS)

    Mennell, R.; Rogge, R.

    1974-01-01

    Wind tunnel aerodynamic investigations were conducted on an 0.015-scale representation of the space shuttle launch configuration. The primary test objectives were to investigate shock wave formation and record the aerodynamic stability and control effects generated by a new external tank nose configuration (MCR 467) at a Mach number of 1.2. Schlieren photographs were taken at angles of attack of -4 deg, 0 deg, and 4 deg, beta = 0 deg with force and pressure data recorded over the alpha range of -4 deg equal to or less than alpha equal to or less than 4 deg at beta = + or - 4 deg. The launch configuration model, consisting of the VL70-00014OA/B Orbiter, the VL78-000041B ET, and the VL77-000036A SRBs, was sting mounted on a 2.5-inch Task type internal balance entering through the ET base region. Wing, body, and base pressure lines for all orifices were routed internally through the model to the sting support system. Parametric variation consisted only of altering the ET nose configuration.

  9. AWOS Data Acquisition System (ADAS), Automated Lightning Detection and Reporting System (ALDARS), Operational Test and Evaluation (OT & E) Final Test Report.

    DTIC Science & Technology

    1998-12-01

    08/18/97 201_: 213 :_ 17 ____-.. JADAS ) :„08/i.8^_9J72£i23_^J_._msg_s 30 " ’ Hdr: Sim-9 j ADU size: 2117 | Type: ITWS4 Awos | ID: KACY | OMO’s...KACY | OMO’s = 0x03 ...K„002.K00.3 KOOl ## New ADU ## INPUT MESSAGE #: 10 ADU#: 10 j TIME - (IPS)’: 08/18/97 20:23: lj...-. JADAS ) •08/18/9720:23:18...CR4 INPUT MESSAGE #: 158 ’’"’’RECEIVE’’ TIME JADAS ] : 08/19/97 18:11:16 21378 RMS"ID7 ’ ""ÖxÖT" "" LOGICAL UNIT ID.: 0x20

  10. Favorable environments for the occurrence of overshooting tops in tropical cyclones

    NASA Astrophysics Data System (ADS)

    Sun, Liangxiao; Zhuge, Xiaoyong; Wang, Yuan

    2017-04-01

    Based on Multifunctional Transport Satellite data and the infrared window-texture detection algorithm, the level of overshooting top (OT) activity within a tropical cyclone (TC), which is defined as the hourly mean number of OT occurrence, was statistically investigated in the western North Pacific basin for the period 2005-12. Based on the level of OT activity, the samples were divided into OT and non-OT cases or high-activity-OT (HA-OT) and low-activity-OT (LA-OT) cases. The differences in large-scale environmental variables between OT (HA-OT) and non-OT (LA-OT) cases were examined 12 hours prior to the OT occurrence. Statistical analysis showed that environmental differences did exist between the OT and non-OT cases. The OTs were more skewed towards the early stage of the TC life cycle, and mostly concentrated in low latitudes. Meanwhile, a sufficiently deep warm-water layer, large temperature difference between the upper- and lower-level troposphere, large humidity at the middle and upper levels, and large atmospheric instability, were favorable for OT occurrence. The differences in large-scale environmental characteristics between HA-OTs and LA-OTs were not as significant as those between OTs and non-OTs, but the HA-OT samples tended to occur when the vertical shear was weak and the TC intensity was low. Finally, statistical models were designed to predict the OT and HA-OT. When at least three OT (HA-OT) predictor thresholds were satisfied, the Peirce skill score reached a maximum value of 0.49 (0.30).

  11. Orthostatic tremor in progressive supranuclear palsy.

    PubMed

    de Bie, Rob M A; Chen, Robert; Lang, Anthony E

    2007-06-15

    Patients with orthostatic tremor (OT) can be classified as having "primary OT," with or without postural arm tremor but no other abnormal neurological features, or "OT plus." We describe a patient with OT, with postural tremor of the arms and restless legs syndrome (RLS), who developed features typical of progressive supranuclear palsy (PSP). PSP can be accompanied by OT.

  12. 76 FR 31680 - General Reporting and Recordkeeping by Savings Associations and Savings and Loan Holding Companies

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-01

    ... infocollection.comments@ots.treas.gov . OTS will post comments and the related index on the OTS Internet Site at... (Regulation Z, truth in lending), 12 CFR part 202 (Regulation B, Equal Credit Opportunity Act), 12 CFR...

  13. 75 FR 34533 - Deposits

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-17

    ... infocollection.comments@ots.treas.gov . OTS will post comments and the related index on the OTS Internet Site at... savings associations under Regulation DD. Regulation DD implements the Truth in Savings Act, part of...

  14. 76 FR 16477 - General Reporting and Recordkeeping by Savings Associations and Savings and Loan Holding Companies

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-23

    ... infocollection.comments@ots.treas.gov . OTS will post comments and the related ] index on the OTS Internet Site... each savings and loan holding company), 12 CFR part 226 (Regulation Z, truth in lending), 12 CFR...

  15. A New Population of Parvocellular Oxytocin Neurons Controlling Magnocellular Neuron Activity and Inflammatory Pain Processing.

    PubMed

    Eliava, Marina; Melchior, Meggane; Knobloch-Bollmann, H Sophie; Wahis, Jérôme; da Silva Gouveia, Miriam; Tang, Yan; Ciobanu, Alexandru Cristian; Triana del Rio, Rodrigo; Roth, Lena C; Althammer, Ferdinand; Chavant, Virginie; Goumon, Yannick; Gruber, Tim; Petit-Demoulière, Nathalie; Busnelli, Marta; Chini, Bice; Tan, Linette L; Mitre, Mariela; Froemke, Robert C; Chao, Moses V; Giese, Günter; Sprengel, Rolf; Kuner, Rohini; Poisbeau, Pierrick; Seeburg, Peter H; Stoop, Ron; Charlet, Alexandre; Grinevich, Valery

    2016-03-16

    Oxytocin (OT) is a neuropeptide elaborated by the hypothalamic paraventricular (PVN) and supraoptic (SON) nuclei. Magnocellular OT neurons of these nuclei innervate numerous forebrain regions and release OT into the blood from the posterior pituitary. The PVN also harbors parvocellular OT cells that project to the brainstem and spinal cord, but their function has not been directly assessed. Here, we identified a subset of approximately 30 parvocellular OT neurons, with collateral projections onto magnocellular OT neurons and neurons of deep layers of the spinal cord. Evoked OT release from these OT neurons suppresses nociception and promotes analgesia in an animal model of inflammatory pain. Our findings identify a new population of OT neurons that modulates nociception in a two tier process: (1) directly by release of OT from axons onto sensory spinal cord neurons and inhibiting their activity and (2) indirectly by stimulating OT release from SON neurons into the periphery.

  16. Oxytocin and autistic disorder: alterations in peptide forms.

    PubMed

    Green, L; Fein, D; Modahl, C; Feinstein, C; Waterhouse, L; Morris, M

    2001-10-15

    Oxytocin (OT) is synthesized as a prohormone that is sequentially processed to peptides. These peptides are the bioactive amidated form (OT) and the C-terminal extended peptides, OT-Gly, OT-Gly-Lys and OT-Gly-Lys-Arg, which are designated together as OT-X. As an extension of our previous study finding decreased plasma OT in autism, studies were conducted to determine whether there were changes in OT peptide forms in autistic children. Twenty eight male subjects (97 +/- 20 months; range, 70-139 months), diagnosed with DSM-IV autistic disorder through observation and semi-structured interview, were compared with 31 age-matched nonpsychiatric control subjects (106 +/- 22 months; range, 74-140 months). Using OT antisera with different specificity for the peptide forms, we measured plasma OT and OT-X in each group. T tests showed that there was a decrease in plasma OT (t = 4.4, p <.0001), an increase in OT-X (t = 2.3, p <.03) and an increase in the ratio of OT-X/OT (t = 4.5, p <.0001) in the autistic sample, compared with control subjects. The results suggest that children with autistic disorder show alterations in the endocrine OT system. Deficits in OT peptide processing in children with autism may be important in the development of this syndrome.

  17. JETCAL 2000R Analyzer H337PA-603 Operational Test and Evaluation (OT&E) on H-53 E/J Aircraft and H46 D/E Aircraft

    DTIC Science & Technology

    2003-01-28

    ost s W hen C O SS I is Im ple m en ted 19 ,517 17 ,580 15 ,161 14 ,639 14 ,018 13 ,597 13 ,188 12...n t V a l u e ( $ K ) C. Ma rg in al I n vestm en t D. Mar gina l Savin gs Cost Com p ar ison -- Sho w ing Do D I n vestm en t s a nd Savin...copies GE AIRCRAFT ENgINES, 1000 WESTERN AVE., LYNN, MA 01910 Attention: Mr. William Meyer, T64 engines and Mr. Gordon Gissel , T58 engines A-1

  18. Innovative Clean Coal Technology (ICCT). Demonstration of Selective Catalytic Reduction (SCR) technology for the control of nitrogen oxide (NO{sub x}) emissions from high-sulfur coal-fired boilers: Volume 3, Appendices O--T. Final report

    SciTech Connect

    1996-10-01

    Volume 3 contains the following appendices: Appendix O, Second Series-Manual APH Tests; Appendix P, Third Series-Manual APH Tests; Appendix Q, ABB Analysis of Air Preheaters-Final Report; Appendix R, ABB Corrosion Analysis Study; Appendix S, SRI Waste Stream Impacts Study; and Appendix T, Economic Evaluation.

  19. Results of an external tank separation test in AEDC/VKF tunnel B on 0.010-scale replica of space shuttle vehicle model 52-OT(IA17A), Volume 1

    NASA Technical Reports Server (NTRS)

    Spangler, R. H.; Daileda, J. J.

    1975-01-01

    Tests were conducted on scale models of the space shuttle orbiter and external tank (ET) to determine the aerodynamic interactions during a return to launch site abort separation. The orbiter model was built to vehicle 3 configuration lines (139B) and the ET model approximated the vehicle 5 configurations with protuberances and attach hardware. For these investigations the orbiter was mounted on the primary support system and the external tank was mounted on the captive trajectory system. Six-component data were obtained for each vehicle at various orbiter angles of attack and sideslip for a range of relative angular and linear displacements of the ET from the orbiter.

  20. Results of investigations of an 0.010-scale 140A/B configuration (model 72-OTS) of the Rockwell International space shuttle orbiter in the NASA/Langley Research Center unitary plan wind tunnel

    NASA Technical Reports Server (NTRS)

    Petrozzi, M. T.; Milam, M. D.

    1975-01-01

    Experimental aerodynamic investigations were conducted in the NASA/Langley unitary plan wind tunnel on a sting mounted 0.010-scale outer mold line model of the 140A/B configuration of the Rockwell International Space Shuttle Vehicle. The primary test objectives were to obtain: (1) six component force and moment data for the mated vehicle at subsonic and transonic conditions, (2) effects of configuration build-up, (3) effects of protuberances, ET/orbiter fairings and attach structures, and (4) elevon deflection effects on wing bending moment. Six component aerodynamic force and moment data and base and balance cavity pressures were recorded over Mach numbers of 1.6, 2.0, 2.5, 2.86, 3.9, and 4.63 at a nominal Reynolds number of 20 to the 6th power per foot. Selected configurations were tested at angles of attack and sideslip from -10 deg to +10 deg. For all configurations involving the orbiter, wing bending, and torsion coefficients were measured on the right wing.

  1. Results of an investigation of Reynolds effects on integrated vehicle elevon hinge moments and wing panel loads obtained with 0.010 scale model 72 OTS in the Rockwell trisonic wind tunnel (IA141)

    NASA Technical Reports Server (NTRS)

    Mennell, R. C.

    1976-01-01

    Wind tunnel investigations were conducted on an 0.010-scale representation of the VL70-000140C Integrated Space Shuttle Launch Vehicle. The primary test objective was to obtain Reynolds number effects on orbiter elevon hinge moments and wing bending/torsional moments. Launch vehicle aerodynamic force data were also recorded. The elevon hinge moments, wing bending/torsional moments, and vehicle force data were recorded over an angle of attack range of -6 deg to +6 deg, an angle of sideslip range of -6 deg to +6 deg, at Mach numbers of 0.6, 0.975, 1.05 and 1.25. The Reynolds number was varied from a minimum of 4.5 million/foot to a maximum of 11.5 million/foot. The complete integrated configuration was tested with the orbiter elevons set at 0 deg and deflected to 9 deg on the outboard elevon and 10 deg on the inboard elevon. Testing was conducted in the TWT 19.7% porous transonic test section with the model sting mounted through the orbiter base. All aerodynamic force data were obtained from internal strain gage balance located in the orbiter.

  2. Base pressure and heat transfer tests of the 0.0225-scale space shuttle plume simulation model (19-OTS) in yawed flight conditions in the NASA-Lewis 10x10-foot supersonic wind tunnel (test IH83)

    NASA Technical Reports Server (NTRS)

    Foust, J. W.

    1979-01-01

    Wind tunnel tests were performed to determine pressures, heat transfer rates, and gas recovery temperatures in the base region of a rocket firing model of the space shuttle integrated vehicle during simulated yawed flight conditions. First and second stage flight of the space shuttle were simulated by firing the main engines in conjunction with the SRB rocket motors or only the SSME's into the continuous tunnel airstream. For the correct rocket plume environment, the simulated altitude pressures were halved to maintain the rocket chamber/altitude pressure ratio. Tunnel freestream Mach numbers from 2.2 to 3.5 were simulated over an altitude range of 60 to 130 thousand feet with varying angle of attack, yaw angle, nozzle gimbal angle and SRB chamber pressure. Gas recovery temperature data derived from nine gas temperature probe runs are presented. The model configuration, instrumentation, test procedures, and data reduction are described.

  3. Wind tunnel tests of an 0.019-scale space shuttle integrated vehicle -2A configuration (model 14-OTS) in the NASA Ames 8 X 7 foot unitary wind tunnel, volume 2. [cold jet gas plumes and pressure distribution

    NASA Technical Reports Server (NTRS)

    Hardin, R. B.; Burrows, R. R.

    1975-01-01

    The purpose of the test was to determine the effects of cold jet gas plumes on (1) the integrated vehicle longitudinal and lateral-directional force data, (2) exposed wing hinge moment, (3) wing pressure distributions, (4) orbiter MPS external pressure distributions, and (5) model base pressures. An investigation was undertaken to determine the similarity between solid and gaseous plumes; fluorescent oil flow visualization studies were also conducted. Plotted wing pressure data is tabulated.

  4. Results of investigations conducted in the LaRC 8-foot transonic pressure tunnel using the 0.010-scale 72-OTS model of the space shuttle integrated vehicle (IA93)

    NASA Technical Reports Server (NTRS)

    Nichols, M. E.

    1976-01-01

    Test procedures, history, and data from the wind tunnel test are presented. Aero-loads were investigated on the updated configuration-5 space shuttle launch vehicle at Mach numbers from 0.600 to 1.205. Six-component vehicle forces and moments, base and sting-cavity pressures, elevon hinge moments, wing-root bending and torsion moments, and normal shear force data were obtained. Full simulation of updated vehicle protuberances and attach hardware was employed. Various elevon deflection angles were tested with two different forward orbiter-to-external-tank attach-strut configurations. The entire model was supported by means of a balance mounted in the orbiter through its base and suspended from a sting.

  5. Results of investigations conducted in the LaRC 8-foot transonic pressure tunnel using the 0.010-scale 72-OTS model of the space shuttle integrated vehicle (IA93), volume 2

    NASA Technical Reports Server (NTRS)

    Nichols, M. E.

    1976-01-01

    Test procedures, history, and plotted coefficient data are presented for an aero-loads investigation on the updated configuration-5 space shuttle launch vehicle at Mach numbers from 0.600 to 1.205. Six-component vehicle forces and moments, base and sting-cavity pressures, elevon hinge moments, wing-root bending and torsion moments, and normal shear force data were obtained. Full simulation of updated vehicle protuberances and attach hardware was employed.

  6. Results of heat transfer tests of an 0.0175-scale space shuttle vehicle model 22 OTS in the NASA-Ames 3.5 foot hypersonic wind tunnel (IH3), volume 1

    NASA Technical Reports Server (NTRS)

    Foster, T. F.; Lockman, W. K.

    1975-01-01

    Heat transfer data for the 0.0175-scale space shuttle vehicle 3 are presented. Interference heating effects were investigated by a model build-up technique of orbiter alone, tank alone, second, and first stage configurations. The test program was conducted in the NASA-Ames 3.5-foot hypersonic wind tunnel at Mach 5.3 for nominal free stream Reynolds number per foot values of 1.5, and 5.0 million.

  7. Results of transonic wind tunnel tests on an 0.010-scale space shuttle mated vehicle model 72-OTS in the LaRC 8-foot TPT (IA43)

    NASA Technical Reports Server (NTRS)

    Petrozzi, M. T.; Milam, M. D.

    1975-01-01

    Experimental aerodynamic investigations were conducted in NASA/Langley 8-Foot transonic pressure tunnel on a sting mounted 0.010-scale outer mold line model of 104A/B configuration of the Rockwell International space shuttle vehicle. Component aerodynamic force and moment data and base and balance cavity pressures were recorded over an angle of attack range of -10 deg to +10 deg at Mach numbers of 0.6, 0.8, 0.9, 0.98, 1.13, and 1.2. Selected configurations were tested at sideslip angles from -10 deg to +10 deg. For all configurations involving the orbit, wing bending and torsion were measured on the right wing. Inboard elevon setting of 0 deg, +4 deg and +8 deg and outboard settings of 0 deg, +4 deg and +8 deg were tested.

  8. Supersonic tests of an 0.015 scale space shuttle mated vehicle model (67-OTS) in the LaRC UPWT to obtain aerodynamic force data (IA42A/B)

    NASA Technical Reports Server (NTRS)

    Hardin, R.; Burrows, R. R.

    1974-01-01

    Wind tunnel tests were conducted of the NASA/Rockwell 0.015 scale configuration 4 mated space shuttle vehicle. Data were obtained for a range of Mach numbers from 1.60 to 4.63 and angles of attack from minus 10 degrees to plus 10 degrees. A complete model build-up was performed. Longitudinal and lateral directional stability and control data were obtained for the tank alone, tank plus solid rocket boosters, and mated configuration of tank plus orbiter plus solid rocket boosters. Single component rudder hinge moment data were obtained at rudder deflections of zero degrees and minus 20 degrees for each Mach number tested.

  9. Wind tunnel tests of an 0.019-scale space shuttle integrated vehicle -2A configuration (model 14-OTS) in the NASA Ames 8 by 7 foot unitary wind tunnel (IA12C), volume 1. [torque and exhaust gases

    NASA Technical Reports Server (NTRS)

    Hardin, R. B.; Burrows, R. R.

    1975-01-01

    The purpose of the test was to determine the effects of cold jet gas plumes on (1) the integrated vehicle longitudinal and lateral-directional force data, (2) exposed wing hinge moment, (3) wing pressure distributions, (4) orbiter MPS external pressure distributions, and (5) model base pressure. The similarity between solid and gaseous plumes was investigated, and fluorescent oil flow visualization studies were conducted.

  10. Results of wind tunnel tests of an ASRM configured 0.03 scale Space Shuttle integrated vehicle model (47-OTS) in the AEDC 16-foot transonic wind tunnel, volume 2

    NASA Technical Reports Server (NTRS)

    Marroquin, J.; Lemoine, P.

    1992-01-01

    An experimental Aerodynamic and Aero-Acoustic loads data base was obtained at transonic Mach numbers for the Space Shuttle Launch Vehicle configured with the ASRM Solid Rocket Boosters as an increment to the current flight configuration (RSRB). These data were obtained during transonic wind tunnel tests (IA 613A) conducted in the Arnold Engineering Development Center 16-Foot transonic propulsion wind tunnel from March 27, 1991 through April 12, 1991. This test is the first of a series of two tests covering the Mach range from 0.6 to 3.5. Steady state surface static and fluctuating pressure distributions over the Orbiter, External Tank and Solid Rocket Boosters of the Shuttle Integrated Vehicle were measured. Total Orbiter forces, Wing forces and Elevon hinge moments were directly measured as well from force balances. Two configurations of Solid Rocket Boosters were tested, the Redesigned Solid Rocket Booster (RSRB) and the Advanced Solid Rocket Motor (ASRM). The effects of the position (i.e., top, bottom, top and bottom) of the Integrated Electronics Assembly (IEA) box, mounted on the SRB attach ring, were obtained on the ASRM configured model. These data were obtained with and without Solid Plume Simulators which, when used, matched as close as possible the flight derived pressures on the Orbiter and External Tank base. Data were obtained at Mach numbers ranging from 0.6 to 1.55 at a Unit Reynolds Number of 2.5 million per foot through model angles of attack from -8 to +4 degrees at sideslip angles of 0, +4 and -4 degrees.

  11. Results of heat transfer tests of an 0.0175-scale space shuttle vehicle model 22 OTS in the NASA-Ames 3.5-foot hypersonic wind tunnel (IH3), volume 3

    NASA Technical Reports Server (NTRS)

    Foster, T. F.; Lockman, W. K.

    1975-01-01

    Heat-transfer data for the 0.0175-scale space shuttle vehicle 3 are presented, and interference heating effects were investigated by a model build-up technique of the orbiter. The test program was conducted at Mach 5.3 for nominal free-stream Reynolds number per foot values of 1,500,000 and 5,000,000.

  12. Results of oil flow visualization tests of an 0.010-scale model (52-OT) of the space shuttle orbiter-tank mated and orbiter configurations in the AEDC VKF tunnel B (IA17B)

    NASA Technical Reports Server (NTRS)

    Daileda, J. J.

    1975-01-01

    An 0.010-scale model of the space shuttle (orbiter-tank mated and orbiter configurations) was tested in the AEDC VKF Tunnel B to investigate aerodynamic flow patterns. The tests utilized oil flow techniques to visualize the flow patterns. Tunnel free stream Mach number was 7.95 and nominal unit Reynolds number was 3.7 million per foot. Model angle of attack was varied from -5 deg through 10 deg and angle of sideslip was 0 deg and 2 deg. Photographs of resulting oil flow patterns are presented.

  13. Heat transfer tests of an 0.006-scale thin-skin space shuttle thermocouple model (141-OT) in the Langley Research Center Freon tunnel at M-6 (IH18). [wind tunnel tests

    NASA Technical Reports Server (NTRS)

    Walstad, D. G.

    1976-01-01

    Ascent heating data were obtained at conditions simulating real gas effects at hypersonic Mach numbers. The configurations tested were Orbiter alone, external tank alone, and mated Orbiter and external tank. A boundary layer trip investigation was conducted for all configurations. The test was conducted at Mach 6 and Reynolds number of one half million per foot for 0 deg and -5 deg angle-of-attack. Selected thermocouples were chosen from the Orbiter and external tank to be used for obtaining heat transfer measurements. A maximum of 42 thermocouples could be measured by the facility data acquisition at one time and no attempt was made to record the excess thermocouples located on the model. Photographs of the test configurations are shown.

  14. OT1_evileniu_1: Probing the extremes of the outer Solar System: short-term variability of the largest, the densest and the most distant TNOs from PACS photometry

    NASA Astrophysics Data System (ADS)

    Vilenius, E.

    2010-07-01

    Pluto was believed to be the outermost object in the Solar System until, at the end of the last Millenium, a number of similar objects were found on orbits beyond Neptune. These objects are now being designated as Trans-Neptunian Objects (TNOs) and are believed to be a reminder of a primordial population. The TNO population comprises a wide range of orbital types and spectral features, many of which are of icy nature. Their origin and evolution are still an open question and subject to debate. We propose repeated high-SNR PACS photometry observations of three extreme specimen of the TNO population: (136199) Eris, the largest dwarf planet, (90377) Sedna, the most distant body in the Solar System and (50000) Quaoar, the densest TNO observed so far. We request a total of 51.7 hours of Herschel observing time using different channels, aiming a SNR of 10 or higher. We intend to perform time-series photometry in order to refine physical properties, which have often been determined using coarse thermal models and single-band data in the past, to find hints of thermal IR lightcurves of Eris and Sedna and to make a high SNR observation of the entire lightcurve of Quaoar. Together with available optical lightcurves we can distinguish whether flux variations are due to shape effects or inhomogeneities of the object's surface. We will make use of existing thermal and thermophysical models to refine physical properties, which may be used to recompute density estimations for Eris and Quaoar and to model surface compositions. Herschel is highly suitable for this task, since it offers the highest sensitivity available to date in the far-IR regime, in which TNO emission peaks due their low surface temperatures. Our results will put constraints on some of the important questions concerning the Trans-Neptunian region and will therefore be of vital importance for observers and modelers in Solar System sciences.

  15. Results of wind tunnel tests of an ASRM configured 0.03 scale Space Shuttle integrated vehicle model (47-OTS) in the AEDC 16-foot transonic wind tunnel, volume 2

    NASA Astrophysics Data System (ADS)

    Marroquin, J.; Lemoine, P.

    1992-10-01

    An experimental Aerodynamic and Aero-Acoustic loads data base was obtained at transonic Mach numbers for the Space Shuttle Launch Vehicle configured with the ASRM Solid Rocket Boosters as an increment to the current flight configuration (RSRB). These data were obtained during transonic wind tunnel tests (IA 613A) conducted in the Arnold Engineering Development Center 16-Foot transonic propulsion wind tunnel from March 27, 1991 through April 12, 1991. This test is the first of a series of two tests covering the Mach range from 0.6 to 3.5. Steady state surface static and fluctuating pressure distributions over the Orbiter, External Tank and Solid Rocket Boosters of the Shuttle Integrated Vehicle were measured. Total Orbiter forces, Wing forces and Elevon hinge moments were directly measured as well from force balances. Two configurations of Solid Rocket Boosters were tested, the Redesigned Solid Rocket Booster (RSRB) and the Advanced Solid Rocket Motor (ASRM). The effects of the position (i.e., top, bottom, top and bottom) of the Integrated Electronics Assembly (IEA) box, mounted on the SRB attach ring, were obtained on the ASRM configured model. These data were obtained with and without Solid Plume Simulators which, when used, matched as close as possible the flight derived pressures on the Orbiter and External Tank base. Data were obtained at Mach numbers ranging from 0.6 to 1.55 at a Unit Reynolds Number of 2.5 million per foot through model angles of attack from -8 to +4 degrees at sideslip angles of 0, +4 and -4 degrees.

  16. Results of wind tunnel tests of an ASRM configured 0.03 scale Space Shuttle integrated vehicle model (47-OTS) in the AEDC 16-foot Transonic wind tunnel (IA613A), volume 1

    NASA Astrophysics Data System (ADS)

    Marroquin, J.; Lemoine, P.

    1992-10-01

    An experimental Aerodynamic and Aero-Acoustic loads data base was obtained at transonic Mach numbers for the Space Shuttle Launch Vehicle configured with the ASRM Solid Rocket Boosters as an increment to the current flight configuration (RSRB). These data were obtained during transonic wind tunnel tests (IA 613A) conducted in the Arnold Engineering Development Center 16-Foot transonic propulsion wind tunnel from March 27, 1991 through April 12, 1991. This test is the first of a series of two tests covering the Mach range from 0.6 to 3.5. Steady state surface static and fluctuating pressure distributions over the Orbiter, External Tank and Solid Rocket Boosters of the Shuttle Integrated Vehicle were measured. Total Orbiter forces, Wing forces and Elevon hinge moments were directly measured as well from force balances. Two configurations of Solid Rocket Boosters were tested, the Redesigned Solid Rocket Booster (RSRB) and the Advanced Solid Rocket Motor (ASRM). The effects of the position (i.e. top, bottom, top and bottom) of the Integrated Electronics Assembly (IEA) box, mounted on the SRB attach ring, were obtained on the ASRM configured model. These data were obtained with and without Solid Plume Simulators which, when used, matched as close as possible the flight derived pressures on the Orbiter and External Tank base. Data were obtained at Mach numbers ranging from 0.6 to 1.55 at a Unit Reynolds Number of 2.5 million per foot through model angles of attack from -8 to +4 degrees at sideslip angles of 0, +4 and -4 degrees.

  17. Results of Experimental Investigations to Determine External Tank Protuberance Loads Using a 0.03-Scale Model of the Space Shuttle Launch Configuration (Model 47-OTS) in the NASA/ARC Unitary Plan Wind Tunnel, Volume 2

    NASA Technical Reports Server (NTRS)

    Houlihan, S. R.

    1992-01-01

    Data were obtained on a 3-percent model of the Space Shuttle launch vehicle in the NASA/Ames Research Center 11x11-foot and 9x7-foot Unitary Plan Wind Tunnels. This test series has been identified as IA19OA/B and was conducted from 7 Feb. 1980 to 19 Feb. 1980 (IA19OA) and from 17 March 1980 to 19 March 1980 and from 8 May 1980 to 30 May 1980 (IA19OB). The primary test objective was to obtain structural loads on the following external tank protuberances: (1) LO2 feedline; (2) GO2 pressure line; (3) LO2 antigeyser line; (4) GH2 pressure line; (5) LH2 tank cable tray; (6) LO2 tank cable tray; (7) Bipod; (8) ET/SRB cable tray; and (9) Crossbeam/Orbiter cable tray. To fulfill these objectives the following steps were taken: Eight 3-component balances were used to measure forces on various sections of 1 thru 6 above; 315 pressure orifices were distributed over all 9 above items. The LO2 feedline was instrumented with 96 pressure taps and was rotated to four positions to yield 384 pressure measurements. The LO2 antigeyser line was instrumented with 64 pressure taps and was rotated to two positions to yield 128 pressure measurements; Three Chrysler miniature flow direction probes were mounted on a traversing mechanism on the tank upper surface centerline to obtain flow field data between the forward and aft attach structures; and Schlieren photographs and ultraviolet flow photographs were taken at all test conditions. Data from each of the four test phases are presented.

  18. Results of experimental investigations to determine external tank protuberance loads using a 0.03-scale model of the Space Shuttle launch configuration (model 47-OTS) in the NASA/ARC unitary plan wind tunnel, volume 1

    NASA Technical Reports Server (NTRS)

    Houlihan, S. R.

    1992-01-01

    Data were obtained on a 3-percent model of the Space Shuttle launch vehicle in the NASA/Ames Research Center 11x11-foot and 9x7-foot Unitary Plan Wind Tunnels. This test series has been identified as IA190A/B and was conducted from 7 Feb. 1980 to 19 Feb. 1980 (IA190A) and from 17 March 1980 to 19 March 1980 and from 8 May 1980 to 30 May 1980 (IA190B). The primary test objective was to obtain structural loads on the following external tank protuberances: (1) LO2 feedline, (2) GO2 pressure line, (3) LO2 antigeyser line, (4) GH2 pressure line, (5) LH2 tank cable tray, (6) LO2 tank cable tray, (7) Bipod, (8) ET/SRB cable tray, and (9) Crossbeam/Orbiter cable tray. To fulfill these objectives the following steps were taken: (1) Eight 3-component balances were used to measure forces on various sections of 1 thru 6 above. (2) 315 pressure orifices were distributed over all 9 above items. The LO2 feedline was instrumented with 96 pressure taps and was rotated to four positions to yield 384 pressure measurements. The LO2 antigeyser line was instrumented with 64 pressure taps and was rotated to two positions to yield 128 pressure measurements. (3) Three Chrysler miniature flow direction probes were mounted on a traversing mechanism on the tank upper surface centerline to obtain flow field data between the forward and aft attach structures. (4) Schlieren photographs and ultraviolet flow photographs were taken at all test conditions. Data from each of the four test phases are presented.

  19. Heat transfer tests of an 0.006-scale thin-skin space shuttle model (41-OTS) in the Ames 3.5-foot HWT at M equals 5.3 (IH15)

    NASA Technical Reports Server (NTRS)

    Walstad, D. G.; Lockman, W. K.

    1974-01-01

    Data obtained from heat transfer tests of an 0.006-scale space shuttle vehicle in a 3.5-foot hypersonic wind tunnel are presented. The purpose of these tests was to parametrically investigate the ascent heating of the integrated vehicle. Configurations tested were complete for integrated vehicle, orbiter alone, external tank alone, and SRB alone. All configurations were tested with and without transition grit. Testing was conducted at a Mach number of 5.3, and at Reynolds numbers of 2 and 5 million per foot. The angle of attack range varied from 0 to minus 5 degress, execpt for SRB alone, which was tested from minus 5 to 90 degrees. Heat transfer data were obtained from 223 iron-constantan thermocouples attached to thin-skin stainless steel inserts.

  20. Wind tunnel tests of an 0.019-scale space shuttle integrated vehicle -2A configuration (model 14-OTS) in the NASA Ames 8 X 7 foot unitary wind tunnel, volume 3. [cold jet gas plumes and pressure distribution

    NASA Technical Reports Server (NTRS)

    Hardin, R. B.; Burrows, R. R.

    1975-01-01

    Tests were conducted to determine the effects of cold jet gas plumes on (1) the integrated vehicle longitudinal and lateral-directional force data, (2) exposed wing hinge moment, (3) wing pressure distributions, (4) orbiter MPS external pressure distributions, and (5) model base pressures. An investigation was undertaken to determine the similarity between solid and gaseous plumes; fluorescent oil flow visualization studies were also conducted. Tabulated data listings are included.